diff --git a/interpro_active_site/advanced/idx2term.json b/interpro_active_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_active_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_active_site/basic/idx2term.json b/interpro_active_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_active_site/basic/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_active_site/consensus.joblib b/interpro_active_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..70ef7e50c8cb9fedddf44e8c9db57ae862eb2ac5 --- /dev/null +++ b/interpro_active_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0fe1ce2791388f0ee6ef5d3cc046e837dd15c1f8c61c976b8780e8724daf839f +size 76905 diff --git a/interpro_active_site/df_merge.tsv b/interpro_active_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_active_site/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_active_site/metrics.json b/interpro_active_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..2b79c8a98c691d63999ea7388fe681a2d076fcc8 --- /dev/null +++ b/interpro_active_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3381, + "annotations_size": 54, + "title": "Average number of proteins per term", + "value": 2.925925925925926 +} \ No newline at end of file diff --git a/interpro_active_site/paths.json b/interpro_active_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..76047c500b14bfff0caa990d9c720399651a24e4 --- /dev/null +++ b/interpro_active_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C317/C317_val_log2fc"} \ No newline at end of file diff --git a/interpro_active_site/result.tsv b/interpro_active_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..d00a9ec7fa07c85f6a278e4827f57e79eb3303b1 --- /dev/null +++ b/interpro_active_site/result.tsv @@ -0,0 +1,4 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Adenosine/AMP deaminase active site [IPR006650] 0.8123705238236195 0.8804492985949017 0.3786159600690015 0.9999999999930588 0.8411048438342645 2 P00813 1 +ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003] 0.4478843219026858 0.3268865840908463 0.7437536685147121 1.0 0.9987983631012732 4 P06576 1 +Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345] 0.4613791062444593 0.0545515951552852 0.956495702763994 1.0 0.9987983631012732 2 Q9NQ88 1 diff --git a/interpro_active_site/selections.json b/interpro_active_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..4b356aabbf8ded83dca4f407d56f908521deceb5 --- /dev/null +++ b/interpro_active_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "DNA topoisomerase, type IA, active site [IPR023406]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT1", "AKT2", "AMPD2", "APEH", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "AURKB", "BLMH", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CDC34", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CHEK2", "CHUK", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSB", "CTSC", "DLD", "DNMT1", "DUSP3", "EGFR", "EIF2AK2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLUD1", "GSK3B", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "LDHA", "LDHB", "LONP1", "LONP2", "LYN", "MAP2K1", "MAP2K4", "MAPK1", "MAPK3", "MARK2", "MARK3", "MDH1", "MDH2", "MTM1", "MTMR2", "MTMR6", "NEK9", "NME1", "NME2", "NME3", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PREP", "PRKAA1", "PRKACA", "PRKCD", "PRPF4B", "PTK7", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "RNASET2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TAOK3", "TIGAR", "TOP1", "TOP3A", "TPI1", "TPP2", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UMPS", "VRK1", "VRK2", "WNK1", "WNK3", "YES1"], "leading_proteins": ["ADA", "ATP5B", "TIGAR"]} \ No newline at end of file diff --git a/interpro_binding_site/advanced/idx2term.json b/interpro_binding_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_binding_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_binding_site/basic/idx2term.json b/interpro_binding_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..10e8eeba27932c124b42dde09eed12d360760c29 --- /dev/null +++ b/interpro_binding_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "EF-Hand 1, calcium-binding site [IPR018247]", "1": "Beta tubulin, autoregulation binding site [IPR013838]"} \ No newline at end of file diff --git a/interpro_binding_site/basic/plot_0.png b/interpro_binding_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..1590a45dce00df65aee997bfe80194797060805e --- /dev/null +++ b/interpro_binding_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3778650f167d8682438e8c1c2ac407f064abf968d85aa6d9584b8181987bb8d6 +size 131815 diff --git a/interpro_binding_site/basic/plot_1.png b/interpro_binding_site/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..fb3f2deed244964a06691d9740ad440eddf43898 --- /dev/null +++ b/interpro_binding_site/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8a59fc0bd99a5ccd54aa335b27ced0f1d4aa4d751a968176f0d86b8e4bbef286 +size 140017 diff --git a/interpro_binding_site/consensus.joblib b/interpro_binding_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..04d2c5a2fa5db4bf39b2454a4fb8b3450c49cefc --- /dev/null +++ b/interpro_binding_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:39d53f14c6aa091d0480c726307f81aa900022aeefc68ca7714316ab49623747 +size 76337 diff --git a/interpro_binding_site/df_merge.tsv b/interpro_binding_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_binding_site/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_binding_site/metrics.json b/interpro_binding_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..ca71c519d12a7c9c28c19191a8433fcb4371ada0 --- /dev/null +++ b/interpro_binding_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3381, + "annotations_size": 32, + "title": "Average number of proteins per term", + "value": 4.8125 +} \ No newline at end of file diff --git a/interpro_binding_site/paths.json b/interpro_binding_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..2f3a5bd212de3b6343045397296271ca22797050 --- /dev/null +++ b/interpro_binding_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C317/C317_val_log2fc"} \ No newline at end of file diff --git a/interpro_binding_site/result.tsv b/interpro_binding_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..a7cf135da70f09b5e80b97890a5bfbe2254a4baa --- /dev/null +++ b/interpro_binding_site/result.tsv @@ -0,0 +1,5 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +EF-Hand 1, calcium-binding site [IPR018247] 0.4829848149067728 1.5943389334988092 0.1108601419072587 0.976716807365923 0.3547524541032281 40 Q13813,Q96AY3,O95302,P0DP25,P80303,Q96D71,Q9Y680,P43304,P12814,Q14257,Q9NWM8,O43852,P41208,Q9BPX6 14 +Peptidase M16, zinc-binding site [IPR001431] 0.5839626824824431 0.9911025214418816 0.3216355219185045 0.9999959559254822 0.6626349644238729 5 Q10713,P22695 2 +IQ motif, EF-hand binding site [IPR000048] 0.3787210114198547 0.4108488395381209 0.6811833784063961 1.0 0.9082445045418616 11 P35579,P35580,Q7Z406 3 +Beta tubulin, autoregulation binding site [IPR013838] 0.3407407407407445 0.1526431394111993 0.8786797032852867 1.0 0.951750008858642 6 P68371,P07437,Q13509,Q13885,Q9BUF5 5 diff --git a/interpro_binding_site/selections.json b/interpro_binding_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..588cd78edbc9221d5f918a840c69dbc7bebab791 --- /dev/null +++ b/interpro_binding_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Legume lectin, beta chain, Mn/Ca-binding site [IPR019825]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT1", "AKT2", "APEX1", "APOBEC3C", "ARG2", "AURKB", "BPNT1", "CALM3", "CALU", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CAPNS1", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CETN2", "CHUK", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DLAT", "DLST", "DST", "EGFR", "EHD1", "EHD4", "EIF2AK2", "EPHA7", "EPS15", "EPS15L1", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQGAP1", "IQGAP2", "LETM1", "LRP2", "LYN", "MACF1", "MAP2K1", "MAP2K4", "MAPK1", "MAPK14", "MAPK3", "MARK2", "MARK3", "MCCC1", "MICU1", "MYH10", "MYH14", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXSR1", "PA2G4", "PAK2", "PAK4", "PC", "PCCA", "PDCD6", "PDP1", "PEF1", "PGD", "PKMYT1", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1F", "PPM1G", "PRKAA1", "PRKACA", "PRKCD", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "STK4", "TAOK3", "TKT", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4B", "TUBB6", "UBE3C", "UQCRC2", "VRK1", "YES1"], "leading_proteins": ["ACTN1", "CALM3", "CALU", "CETN2", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "GPD2", "MICU1", "MYH10", "MYH14", "MYH9", "NUCB2", "PMPCA", "RCN2", "REPS1", "SPTAN1", "TUBB", "TUBB2A", "TUBB3", "TUBB4B", "TUBB6", "UQCRC2"]} \ No newline at end of file diff --git a/interpro_conserved_site/advanced/idx2term.json b/interpro_conserved_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..ca98c5f36594d004e9f56b6e8f5417cc59668809 --- /dev/null +++ b/interpro_conserved_site/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Proteasome beta-type subunit, conserved site [IPR016050]", "1": "Intermediate filament protein, conserved site [IPR018039]"} \ No newline at end of file diff --git a/interpro_conserved_site/advanced/plot_0.png b/interpro_conserved_site/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..167d20ee2d0b062a7c20bff141925a5f840e28fc --- /dev/null +++ b/interpro_conserved_site/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c6450f63d570e7bc34c8cf6f0ddfa6908e08b8a97a42e36427e76e7ca292c3e2 +size 194739 diff --git a/interpro_conserved_site/advanced/plot_1.png b/interpro_conserved_site/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..4977f15ed5262eb400244efdfd9614345805907a --- /dev/null +++ b/interpro_conserved_site/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4bd8739b8baa8ce2db96cd4d06d5f17141c293f5dce8b74c7bac95f41c2ff527 +size 192264 diff --git a/interpro_conserved_site/basic/idx2term.json b/interpro_conserved_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..c09a26e9e324de8533bad7444e559f1d61f38c80 --- /dev/null +++ b/interpro_conserved_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Proteasome beta-type subunit, conserved site [IPR016050]", "1": "Intermediate filament protein, conserved site [IPR018039]", "2": "Guanylate kinase, conserved site [IPR020590]", "3": "Thioredoxin, conserved site [IPR017937]", "4": "14-3-3 protein, conserved site [IPR023409]", "5": "Zinc finger, RING-type, conserved site [IPR017907]", "6": "Tubulin, conserved site [IPR017975]"} \ No newline at end of file diff --git a/interpro_conserved_site/basic/plot_0.png b/interpro_conserved_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..8765e22c8c15a2575f0e311a9dbdab2600def17c --- /dev/null +++ b/interpro_conserved_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f05001dd082e0ea7db7e33311d7687c9d9fdb846844b48daa99179af988c933c +size 144628 diff --git a/interpro_conserved_site/basic/plot_1.png b/interpro_conserved_site/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..2ac33a423e0eb1ac2652286828cba3513d2b81fc --- /dev/null +++ b/interpro_conserved_site/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid 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/dev/null +++ b/interpro_conserved_site/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9eabe40374148a122d40b7bce736e66f6d997eeb43cb436b8e8514b3fb9405a2 +size 134736 diff --git a/interpro_conserved_site/consensus.joblib b/interpro_conserved_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..d7635085daae2615331fba547279e39648cb4be8 --- /dev/null +++ b/interpro_conserved_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c5bcbd284adc8c37c2c5e9a2fbf69d8f97e4a67959c5892dd12fc6970db6b3ed +size 84109 diff --git a/interpro_conserved_site/df_merge.tsv b/interpro_conserved_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..713049dd8971e99c923b61d41cd6bd01110df4fa --- /dev/null +++ b/interpro_conserved_site/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Proteasome beta-type subunit, conserved site [IPR016050] 5 8 2.235412009024267 0.0253903124290246 3.7135922330097086 7.970873786407767 1.4913184573846054 0.1902243906475925 1.515457478026574 0.1681602725795027 1.0170822776023185 0.2455850375425174 0.1160984687124442 0.0470522829573702 0.0921025797166938 0.0015031185668187 2.312503759377148e-06 +Intermediate filament protein, conserved site [IPR018039] 6 8 2.051930162936926 0.0401764499862096 4.060679611650485 7.546116504854369 0.7869831563787604 0.2926647109331939 1.9153715257926656 0.8924219614624045 1.3691577499316503 0.3120813432784052 0.0200671750728259 1.0 0.1596960736798767 0.0088528623379573 0.0098879726868235 diff --git a/interpro_conserved_site/metrics.json b/interpro_conserved_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..c215033d5575780b6b88f463e604bd14cd34ff3a --- /dev/null +++ b/interpro_conserved_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3381, + "annotations_size": 283, + "title": "Average number of proteins per term", + "value": 2.791519434628975 +} \ No newline at end of file diff --git a/interpro_conserved_site/paths.json b/interpro_conserved_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..5025adf2b0f925eee39a152a888e728dccd36576 --- /dev/null +++ b/interpro_conserved_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C317/C317_val_log2fc"} \ No newline at end of file diff --git a/interpro_conserved_site/result.tsv b/interpro_conserved_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..23070ec191ee603da5204f62b516c80d22384f4b --- /dev/null +++ b/interpro_conserved_site/result.tsv @@ -0,0 +1,31 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Proteasome beta-type subunit, conserved site [IPR016050] 0.7794112291853442 2.235412009024267 0.0253903124290246 0.9993096093950568 0.4628014104585141 8 P28072,P28070,P28074,P20618,P49721 5 +Intermediate filament protein, conserved site [IPR018039] 0.7402602374484524 2.051930162936926 0.0401764499862096 0.999990876391978 0.4628014104585141 8 P07197,P07196,P08670,P48681,Q16352,Q03252 6 +Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364] 0.8357422111735023 1.859769886608786 0.0629180895531755 0.9999999896950033 0.4628014104585141 4 Q8N4Q0 1 +Syntaxin/epimorphin, conserved site [IPR006012] 0.7120931379000216 1.8297641937004792 0.067285207159303 0.9999999972525568 0.4628014104585141 7 O43752,Q9P2W9,Q13277 3 +Ubiquitin specific protease, conserved site [IPR018200] 0.5817202241352242 1.6511748292255115 0.0987028812228136 0.9999999999998312 0.5202414231202954 12 Q9Y4E8,Q96K76 2 +Guanylate kinase, conserved site [IPR020590] 0.6711156643210027 1.6367065839650097 0.101691792618199 0.999999999999934 0.5202414231202954 7 Q9NZW5,O14936,Q00013,Q8N3R9,Q14168 5 +Haem oxygenase conserved site [IPR018207] 0.979875702870672 1.526265966042433 0.1269436409309055 1.0 0.5702388949753373 2 P30519 1 +Mini-chromosome maintenance, conserved site [IPR018525] 0.5796766122654664 1.13703945625699 0.2555217917010539 1.0 0.7295680779738757 6 P33993,P33991,P25205 3 +HMG box A DNA-binding domain, conserved site [IPR017967] 0.6835904657219464 0.900188696762713 0.3680198403700294 1.0 0.8914995505269695 3 P09429 1 +Chaperonin TCP-1, conserved site [IPR002194] 0.5019419612935798 0.8740619031974802 0.3820845430240627 1.0 0.8914995505269695 8 P49368,P78371 2 +Dynamin, GTPase region, conserved site [IPR019762] 0.8040840485350718 0.8499094698178375 0.3953754202266673 1.0 0.8914995505269695 2 O00429 1 +Aldehyde dehydrogenase, glutamic acid active site [IPR029510] 0.4884828442816266 0.8073818000374765 0.4194465492439421 1.0 0.8914995505269695 8 P30837,P51648 2 +Aldehyde dehydrogenase, cysteine active site [IPR016160] 0.4670056700221435 0.7023496189969755 0.4824611562901508 1.0 0.91573896287197 8 P30837,P51648 2 +Polyprenyl synthetase, conserved site [IPR033749] 0.7620597810002989 0.6992217033116388 0.4844134892281793 1.0 0.91573896287197 2 O95749 1 +Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726] 0.7555489789878693 0.6766142460772164 0.4986507379196592 1.0 0.91573896287197 2 Q07820 1 +Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717] 0.7555489789878693 0.6766142460772164 0.4986507379196592 1.0 0.91573896287197 2 Q07820 1 +Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728] 0.7555489789878693 0.6766142460772164 0.4986507379196592 1.0 0.91573896287197 2 Q07820 1 +Thioredoxin, conserved site [IPR017937] 0.4110512311630735 0.6450486939081866 0.5188956306362926 1.0 0.91573896287197 12 Q96JJ7,P07237,O95881,Q9H1E5,Q9H3N1 5 +DnaJ domain, conserved site [IPR018253] 0.433423979022449 0.6389580420803638 0.5228502275781124 1.0 0.91573896287197 10 Q96KC8 1 +4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900] 0.6466410180526834 0.3420349559831603 0.7323245859097145 1.0 0.9727638010976551 2 P21912 1 +14-3-3 protein, conserved site [IPR023409] 0.3869629629629664 0.2995852009527869 0.7644935739050567 1.0 0.9727638010976551 6 Q04917,P31946,P62258,P63104,P61981 5 +Heat shock protein Hsp90, conserved site [IPR019805] 0.4994079336885799 0.2890422651776736 0.7725490342988701 1.0 0.9727638010976551 3 P14625,P07900 2 +Cyclic nucleotide-binding, conserved site [IPR018488] 0.6229653743711212 0.2834664212033291 0.7768193184672998 1.0 0.9727638010976551 2 P10644 1 +Mitogen-activated protein (MAP) kinase, conserved site [IPR003527] 0.4804618117229231 0.2428762609374652 0.8081012560517 1.0 0.9727638010976551 3 P28482,P27361 2 +Ubiquitin interacting motif [IPR003903] 0.3850710900473876 0.2232654078778357 0.8233289482755821 1.0 0.9727638010976551 5 Q92783,O14964,Q9Y6I3,P42566 4 +Mrp, conserved site [IPR000808] 0.5859721811186802 0.2045531843398846 0.8379212353638541 1.0 0.9727638010976551 2 Q8TB37 1 +Zinc finger, RING-type, conserved site [IPR017907] 0.3137888276312099 0.1647105910453176 0.8691717803965371 1.0 0.9727638010976551 15 Q9UBS8,P19474,Q5VTR2,O75150,Q9Y508 5 +Tubulin, conserved site [IPR017975] 0.3407407407407445 0.1526431394111993 0.8786797032852867 1.0 0.9727638010976551 6 P68371,P07437,Q13509,Q13885,Q9BUF5 5 +Vinculin, conserved site [IPR000633] 0.4746966558153381 0.0629602852745082 0.9497981293064988 1.0 0.9835186061128084 2 P18206 1 +Actin, conserved site [IPR004001] 0.4729209825392209 0.0617522642674383 0.9507601184859082 1.0 0.9835186061128084 2 P61163 1 diff --git a/interpro_conserved_site/selections.json b/interpro_conserved_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..8b0e7b378c8e462be8013c7b57281a22b6af0cdf --- /dev/null +++ b/interpro_conserved_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-2-macroglobulin, conserved site [IPR019742]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Amyloidogenic glycoprotein, copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Clusterin, conserved site [IPR033986]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "Disintegrin, conserved site [IPR018358]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Endonuclease III-like, conserved site-2 [IPR004036]", "Endonuclease III-like, iron-sulphur cluster loop motif [IPR003651]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif [IPR000445]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Homeobox, conserved site [IPR017970]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Pyridoxamine 5'-phosphate oxidase, conserved site [IPR019740]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Rel homology domain, conserved site [IPR030492]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S14, conserved site [IPR018271]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium/solute symporter, conserved site [IPR018212]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]", "tRNA-dihydrouridine synthase, conserved site [IPR018517]"], "available_proteins": ["AAAS", "AACS", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADAM9", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK3", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "APEX1", "APLP2", "APP", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "BAG6", "BAX", "BAZ1A", "BAZ1B", "BAZ2A", "BCAT2", "BCS1L", "BDH2", "BLM", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD2", "BRD3", "BRD4", "BTRC", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CDC40", "CDH2", "CDKAL1", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD3", "CHD4", "CLGN", "CLU", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1B", "CORO1C", "CORO7", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCAF7", "DCP2", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX31", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX6", "DHCR7", "DHFR", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DLG1", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB4", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC21", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DST", "DTYMK", "DUS3L", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EHHADH", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPDR1", "EPHA7", "EPN1", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FARP2", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXK1", "FOXK2", "FUCA1", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GGPS1", "GLA", "GLB1", "GLB1L2", "GLO1", "GMPPA", "GMPPB", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GUF1", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HOXD13", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "ILVBL", "IMPAD1", "IMPDH2", "INA", "INTS12", "IQGAP1", "IQGAP2", "IVD", "KDM2A", "KDM5A", "KDSR", "KIF11", "KIF14", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFC1", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LDLR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRP1", "LRP2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGST2", "MIF", "MKRN2", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPST", "MRC2", "MRPL13", "MRPL24", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFV1", "NEFL", "NEFM", "NES", "NF2", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD1", "NSD2", "NSF", "NTHL1", "NUBP2", "NUBPL", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCDH19", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM3", "PHF14", "PHF3", "PHF8", "PHGDH", "PHIP", "PHRF1", "PI4KA", "PI4KB", "PIK3C2A", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PMS1", "PNP", "PNPLA6", "PNPO", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RCL1", "RDH13", "RDX", "RECQL5", "REL", "RIDA", "RNF114", "RNF14", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RTCA", "RTN4IP1", "S100A10", "S100A11", "SART1", "SBDS", "SCAF11", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC27A2", "SLC27A4", "SLC5A6", "SLIT2", "SMARCA4", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STOM", "STRN", "STX10", "STX12", "STX18", "STX3", "STX5", "STX6", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE2", "TAP1", "TAP2", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLN1", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM21", "TRIM24", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN3", "TSPAN6", "TST", "TTF2", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4B", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBA5", "UHRF1", "USP1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP28", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "WARS", "WARS2", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZMYND8"], "leading_proteins": ["ACTR1A", "ALDH1B1", "ALDH3A2", "CASK", "CCT2", "CCT3", "DNAJC1", "DNM1L", "EPN1", "EPS15", "GGPS1", "HGS", "HMGB1", "HMOX2", "HSP90AA1", "HSP90B1", "INA", "LMNB2", "MAPK1", "MAPK3", "MCL1", "MCM3", "MCM4", "MCM7", 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sha256:7fcbbdb0372cb505e87a5615839c86c56fe6e9f2cf4dd867a63dd5cfbaa5a006 +size 132465 diff --git a/interpro_domain/basic/plot_15.png b/interpro_domain/basic/plot_15.png new file mode 100644 index 0000000000000000000000000000000000000000..739504aade94fcb81ea025407537e8de511ae441 --- /dev/null +++ b/interpro_domain/basic/plot_15.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c8641f35305eec7a05f0cb670a4c8ce265f9d8583831417d9f2e7a926cb5ed79 +size 138277 diff --git a/interpro_domain/basic/plot_16.png b/interpro_domain/basic/plot_16.png new file mode 100644 index 0000000000000000000000000000000000000000..379e8ea4ae16f25c249b31f5b4b98d145836adaa --- /dev/null +++ b/interpro_domain/basic/plot_16.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3e0242096af081d3853ef0d56d7e0632af82923b8c5e472c705638505551da6c +size 135538 diff --git a/interpro_domain/basic/plot_17.png b/interpro_domain/basic/plot_17.png new file mode 100644 index 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sha256:270c5e10a7196a63df3591da303fa8e44cb3d2eafda7fe3688655b1101d8c2a9 +size 130553 diff --git a/interpro_domain/basic/plot_4.png b/interpro_domain/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..98fd1f7f63c9a114331dd45b18c883e8d568b5b9 --- /dev/null +++ b/interpro_domain/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0d0c0c72e5b422995893608a111221c1a4a5d64a6005c305d3d87b252eb58f86 +size 134557 diff --git a/interpro_domain/basic/plot_5.png b/interpro_domain/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..2a169660d2b2d0b7c45812ac9082b33b00e0fb76 --- /dev/null +++ b/interpro_domain/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:042d7ca0175084e5e903236444492bce847f8ca2052915b058b71960007953bd +size 130209 diff --git a/interpro_domain/basic/plot_6.png b/interpro_domain/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..c4f99f6c759f9208d3e9396d4c5c2ad5333e9409 --- /dev/null +++ b/interpro_domain/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:20f05a697778bf23c41af713a054cea4b06cfea0c9625a18d5ea37426ce9fb18 +size 131112 diff --git a/interpro_domain/basic/plot_7.png b/interpro_domain/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..80baf234e9056354ac47c25a34bf155b3c826334 --- /dev/null +++ b/interpro_domain/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:544ae65ab48bf1c7939f005bf069c83e3fb349a64baf5847801bcd3e1a8427ae +size 134216 diff --git a/interpro_domain/basic/plot_8.png b/interpro_domain/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..b99df87381d1ce2139c4762b201a28fa137629f2 --- /dev/null +++ b/interpro_domain/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fcbe7afdb7e7ac504a217ef6ffe21029264e478319a755ce315e191604f491d2 +size 127959 diff --git a/interpro_domain/basic/plot_9.png b/interpro_domain/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..c571a336aaf3525f1cbb9c521d0e5319f935f5d5 --- /dev/null +++ b/interpro_domain/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9b425b079632cbddcb506fed3884ac42340ae0406a62bd621ad6dea32031c12a +size 129776 diff --git a/interpro_domain/consensus.joblib b/interpro_domain/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..a4564e8f21427ecdd22bbc6e03a4a3e9a92103a4 --- /dev/null +++ b/interpro_domain/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4d3e78a8de9ba8cb807e08a6266df4be3c00ca4916880bc46ab6e82c470d4ae9 +size 135367 diff --git a/interpro_domain/df_merge.tsv b/interpro_domain/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..4afd12119e875012a8467771b9aa615a2989a115 --- /dev/null +++ b/interpro_domain/df_merge.tsv @@ -0,0 +1,11 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179] 6 12 2.3740933540210065 0.0175921020245759 3.1262135922330097 10.111650485436892 0.9686720267359892 0.3700536707457866 1.7316562118191232 1.203619216216406 0.9607394322697528 0.3108814801432357 0.0106465592757744 1.0 0.1180585699575878 0.0002054625318554 0.0002504856541451 +K Homology domain, type 1 [IPR004088] 12 26 2.217026317107816 0.0266212932087048 8.5 23.218446601941743 0.4539576731478794 0.576935027430011 4.690674491420825 1.6401661988255969 0.9187340965418598 0.3398774289684012 0.3430128009859742 1.0 0.2802926639431586 0.2000228109389489 0.0054583584483833 +Peptidase M1, membrane alanine aminopeptidase [IPR014782] 2 6 2.1463745148665527 0.0318431109160448 2.121359223300971 5.466019417475728 1.4317001483019938 0.1783942022754649 1.021530403905949 0.5881604361499402 0.986353205880356 0.2226891741813114 9.631703469408072e-05 0.0006219606051344 0.002465796513642 0.0007272762906085 0.0053637976870067 +Aminopeptidase N-like , N-terminal domain [IPR045357] 2 6 2.1463745148665527 0.0318431109160448 2.121359223300971 5.466019417475728 1.4317001483019938 0.1783942022754649 1.021530403905949 0.5881604361499402 0.986353205880356 0.2226891741813114 9.631703469408072e-05 0.0006219606051344 0.002465796513642 0.0007272762906085 0.0053637976870067 +LEM domain [IPR003887] 1 6 2.138766040286787 0.0324546210896599 2.237864077669903 5.759708737864078 0.8787481060627674 0.3228260833428172 1.2758866328838632 0.4653299410110203 1.033781091163317 0.2887768895441466 0.0713572297582373 1.0 0.0563150378970086 0.0082857576662697 0.0312108672695238 +P-type ATPase, haloacid dehalogenase domain [IPR044492] 3 6 2.0877925802438866 0.0368165491671925 2.941747572815534 6.145631067961165 0.9567723497044874 0.2732808833570771 1.8358630293390923 1.459204245106796 1.2102525517005158 0.2943240638910574 0.237888308904226 1.0 0.191600110602388 0.0990342687178565 0.2914565107291916 +Dynamin, N-terminal [IPR045063] 4 6 2.067371003980269 0.0386992083246304 3.0970873786407767 6.975728155339806 0.7379849963606689 0.4199536592827374 1.7349327124234004 0.8151438040285356 0.9001171760244049 0.3234417573977254 1.0 1.0 1.0 1.0 0.0141665154869097 +Dynamin-type guanine nucleotide-binding (G) domain [IPR030381] 4 6 2.067371003980269 0.0386992083246304 3.0970873786407767 6.975728155339806 0.7379849963606689 0.4199536592827374 1.7349327124234004 0.8151438040285356 0.9001171760244049 0.3234417573977254 1.0 1.0 1.0 1.0 0.0141665154869097 +Intermediate filament, rod domain [IPR039008] 6 8 2.051930162936926 0.0401764499862096 4.060679611650485 7.546116504854369 0.7869831563787604 0.2926647109331939 1.9153715257926656 0.8924219614624045 1.3691577499316503 0.3120813432784052 0.0293502839846989 1.0 0.191600110602388 0.0155574138143109 0.020271757680103 +Cyclic nucleotide-binding domain [IPR000595] 2 5 2.0313411315621 0.0422204016506215 1.4902912621359223 4.660194174757281 -0.0126471736913758 0.4102849468515657 0.986512397936728 0.870814795980239 1.213781652340298 0.307139032821674 1.0 1.0 1.0 1.0 0.010684483318579 diff --git a/interpro_domain/metrics.json b/interpro_domain/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..075405d7570ed29415b2441aa132d61025cd0f90 --- /dev/null +++ b/interpro_domain/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3381, + "annotations_size": 2760, + "title": "Average number of proteins per term", + "value": 2.205797101449275 +} \ No newline at end of file diff --git a/interpro_domain/paths.json b/interpro_domain/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..ec3dadf50733e9e61d2cd399264529292f43204a --- /dev/null +++ b/interpro_domain/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C317/C317_val_log2fc"} \ No newline at end of file diff --git a/interpro_domain/result.tsv b/interpro_domain/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..a7e57cfa123ff4b70f583a82b4a0997f1aa89e04 --- /dev/null +++ b/interpro_domain/result.tsv @@ -0,0 +1,234 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179] 0.7110755883554581 2.3740933540210065 0.0175921020245759 1.0 0.6964865410596186 12 P62942,Q96AY3,O95302,Q9Y680,Q9NWM8,Q5T1M5 6 +K Homology domain, type 1 [IPR004088] 0.5691561816981714 2.217026317107816 0.0266212932087048 1.0 0.6964865410596186 26 O75525,Q92945,Q9Y6M1,Q9UNW9,Q9Y2W6,Q07666,P61978,Q13868,Q96PU8,P51116,Q96I24,Q96AE4 12 +ERAP1-like C-terminal domain [IPR024571] 0.9137320926448362 2.1710243290303475 0.0299293333590646 1.0 0.6964865410596186 4 P55786,Q9NZ08 2 +Peptidase M1, membrane alanine aminopeptidase [IPR014782] 0.8007907825564105 2.1463745148665527 0.0318431109160448 1.0 0.6964865410596186 6 P55786,Q9NZ08 2 +Aminopeptidase N-like , N-terminal domain [IPR045357] 0.8007907825564105 2.1463745148665527 0.0318431109160448 1.0 0.6964865410596186 6 P55786,Q9NZ08 2 +LEM domain [IPR003887] 0.7990493285094713 2.138766040286787 0.0324546210896599 1.0 0.6964865410596186 6 Q86XL3 1 +P-type ATPase, haloacid dehalogenase domain [IPR044492] 0.7874198459158005 2.0877925802438866 0.0368165491671925 1.0 0.6964865410596186 6 P16615,Q9HD20,P05023 3 +Intermediate filament head, DNA-binding domain [IPR006821] 0.8922968344682707 2.086403193526824 0.0369421159612533 1.0 0.6964865410596186 4 P07196,P08670 2 +Dynamin, N-terminal [IPR045063] 0.7827787874886721 2.067371003980269 0.0386992083246304 1.0 0.6964865410596186 6 O00429,O60313,Q8IWA4,P50570 4 +Dynamin-type guanine nucleotide-binding (G) domain [IPR030381] 0.7827787874886721 2.067371003980269 0.0386992083246304 1.0 0.6964865410596186 6 O00429,O60313,Q8IWA4,P50570 4 +Intermediate filament, rod domain [IPR039008] 0.7402602374484524 2.051930162936926 0.0401764499862096 1.0 0.6964865410596186 8 P07197,P07196,P08670,P48681,Q16352,Q03252 6 +Cyclic nucleotide-binding domain [IPR000595] 0.8234345239911576 2.0313411315620997 0.0422204016506215 1.0 0.6964865410596186 5 Q8IY17,Q9Y4G8 2 +Reticulon [IPR003388] 0.8751255034760376 2.018098506837906 0.0435810031686352 1.0 0.6964865410596186 4 O95197,Q9NQC3 2 +EF-hand, Ca insensitive [IPR014837] 0.8711874444773462 2.002369979178214 0.0452449547580975 1.0 0.6964865410596186 4 P35609,Q13813,P12814 3 +Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564] 0.9383344452930232 1.8926138060854505 0.0584092463993473 1.0 0.6964865410596186 3 Q13505 1 +Metaxin, glutathione S-transferase domain [IPR033468] 0.9383344452930232 1.8926138060854505 0.0584092463993473 1.0 0.6964865410596186 3 Q13505 1 +Cytochrome b5-like heme/steroid binding domain [IPR001199] 0.7154741516057801 1.8455438658770331 0.0649584635865694 1.0 0.6964865410596186 7 Q9UMX5,O43169,Q8WUJ1 3 +PDZ domain [IPR001478] 0.5160111068157911 1.8159935384324344 0.0693713633280661 1.0 0.6964865410596186 28 O43464,Q96L92,Q96RT1,Q12959,P57105,Q9UDY2,Q9Y4G8,Q9NZW5,Q6ZWJ1,O14936,O14641,Q00013,Q8N3R9,P55196,Q9HD26,Q14168 16 +GOLD domain [IPR009038] 0.7220649494513532 1.7961707910449949 0.0724673585831696 1.0 0.6964865410596186 6 Q15363,Q9Y3A6,Q9BVK6,P49755 4 +HDGF-related, PWWP domain [IPR035496] 0.8965260394913416 1.731097316520563 0.0834344089103342 1.0 0.6964865410596186 3 P51858 1 +Guanylate kinase/L-type calcium channel beta subunit [IPR008145] 0.6542309619717519 1.725720143390585 0.0843977723529987 1.0 0.6964865410596186 9 Q9UDY2,Q9NZW5,O14936,Q00013,Q8N3R9,Q14168 6 +Guanylate kinase-like domain [IPR008144] 0.6542309619717519 1.725720143390585 0.0843977723529987 1.0 0.6964865410596186 9 Q9UDY2,Q9NZW5,O14936,Q00013,Q8N3R9,Q14168 6 +Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862] 0.7508886255924103 1.7228779773341465 0.0849105936436074 1.0 0.6964865410596186 5 Q8IVL6,P13674,Q6PK18,Q32P28 4 +Importin-beta, N-terminal domain [IPR001494] 0.5924725193196242 1.713312858904921 0.0866549979741044 1.0 0.6964865410596186 12 O00410,Q96P70,O95373,P55060,Q8TEX9,Q92973 6 +L27 domain, C-terminal [IPR014775] 0.747681181581042 1.7090446419060028 0.0874426805666575 1.0 0.6964865410596186 5 Q9NZW5,Q14168 2 +Alcohol dehydrogenase, N-terminal [IPR013154] 0.7020698698210746 1.7052929496995932 0.0881398018432748 1.0 0.6964865410596186 6 Q8N4Q0 1 +Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375] 0.8888329336673463 1.7011960882201824 0.0889061721621153 1.0 0.6964865410596186 3 P13798 1 +K Homology domain [IPR004087] 0.4997740363595063 1.6908397631321632 0.0908674105094966 1.0 0.6964865410596186 26 O75525,Q92945,Q9Y6M1,Q9UNW9,Q9Y2W6,Q07666,P61978,Q96PU8,P51116,Q96I24,Q96AE4 11 +Extended PHD (ePHD) domain [IPR034732] 0.790769378212023 1.6763559402683308 0.0936684936581162 1.0 0.6964865410596186 4 Q03164,Q8IWS0 2 +TRAM/LAG1/CLN8 homology domain [IPR006634] 0.8809957439785558 1.670683577171672 0.0947841943969383 1.0 0.6964865410596186 3 Q96G23 1 +Protein kinase, C-terminal [IPR017892] 0.6733298541609691 1.6472196219335846 0.0995129120582718 1.0 0.6964865410596186 7 P31751,P31749 2 +CYRIA/CYRIB, Rac1 binding domain [IPR009828] 0.8711529610767252 1.6322942215984346 0.1026175199461756 1.0 0.6964865410596186 3 Q9NUQ9 1 +Tim10-like [IPR004217] 0.7799822327509576 1.6319953921049506 0.1026804568987871 1.0 0.6964865410596186 4 Q9Y5J7,Q9Y5J9,O60220 3 +NOPS [IPR012975] 0.869449378330371 1.6256425190503352 0.1040257245524469 1.0 0.6964865410596186 3 P23246,Q8WXF1 2 +Proteasome activator PA28, C-terminal domain [IPR003186] 0.8626406157489638 1.599037263341476 0.1098123230513268 1.0 0.6964865410596186 3 P61289,Q06323 2 +Proteasome activator PA28, N-terminal domain [IPR003185] 0.8626406157489638 1.599037263341476 0.1098123230513268 1.0 0.6964865410596186 3 P61289,Q06323 2 +Myosin tail [IPR002928] 0.7189597372721505 1.5845269687475694 0.1130738494939134 1.0 0.6964865410596186 5 P35579,P35580,Q7Z406 3 +Polyketide synthase, enoylreductase domain [IPR020843] 0.6431418575543606 1.5814188215872913 0.1137823067444281 1.0 0.6964865410596186 8 Q8N4Q0 1 +Cation-transporting P-type ATPase, C-terminal [IPR006068] 0.765736278301406 1.573221299316449 0.115667585090105 1.0 0.6964865410596186 4 P16615,P05023 2 +Cation-transporting P-type ATPase, N-terminal [IPR004014] 0.765736278301406 1.573221299316449 0.115667585090105 1.0 0.6964865410596186 4 P16615,P05023 2 +Kinesin-like [IPR022164] 0.8534255653933887 1.5629814384397982 0.1180569607533734 1.0 0.6964865410596186 3 Q9Y3P9 1 +L27 domain [IPR004172] 0.6340649487607063 1.5364494389211514 0.1244281893236567 1.0 0.7038281298029563 8 Q12959,Q9NZW5,O14936,Q8N3R9,Q14168 5 +EF-hand domain [IPR002048] 0.4587062998301446 1.487332222381814 0.1369270881593554 1.0 0.7079126295770148 50 P35609,Q13813,Q96AY3,O95302,P0DP25,Q8IYU8,P80303,Q96D71,Q9Y680,P43304,P12814,Q14257,Q9NWM8,O43852,P41208,Q9BPX6 16 +Zinc finger, CHHC-type [IPR012996] 0.8318531675547605 1.4783948596146497 0.1393021204893121 1.0 0.7104369569703484 3 P31943,P52597 2 +Ubiquitin specific protease domain [IPR028889] 0.5388045506961976 1.440181294964398 0.1498161138048952 1.0 0.7149710874800842 13 Q9Y4E8,Q96K76 2 +Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394] 0.5388045506961976 1.440181294964398 0.1498161138048952 1.0 0.7149710874800842 13 Q9Y4E8,Q96K76 2 +Zinc finger, FYVE-related [IPR017455] 0.684000364799692 1.4316148944644238 0.1522540646221273 1.0 0.7149710874800842 5 Q15075,O14964 2 +FYVE zinc finger [IPR000306] 0.684000364799692 1.4316148944644238 0.1522540646221273 1.0 0.7149710874800842 5 Q15075,O14964 2 +Protein Kinase B, pleckstrin homology domain [IPR039026] 0.9508730393607586 1.4126083353837664 0.1577709168433121 1.0 0.7149710874800842 2 P31751 1 +Peptidase M3A/M3B catalytic domain [IPR001567] 0.8132826930791204 1.4054367519629034 0.1598914445259014 1.0 0.7149710874800842 3 P52888 1 +Transcription factor CBF/NF-Y/archaeal histone domain [IPR003958] 0.8125680120313419 1.4026273636668791 0.1607279875959271 1.0 0.7149710874800842 3 Q9NRG0 1 +Myosin, N-terminal, SH3-like [IPR004009] 0.6752624445766902 1.39321334209646 0.163555286340439 1.0 0.7149710874800842 5 P35579,P35580 2 +Oxoglutarate/iron-dependent dioxygenase [IPR005123] 0.604311659863211 1.388119456704353 0.1651006728044484 1.0 0.7149710874800842 8 Q8IVL6,P13674,Q6PK18,Q32P28 4 +Prolyl 4-hydroxylase, alpha subunit [IPR006620] 0.604311659863211 1.388119456704353 0.1651006728044484 1.0 0.7149710874800842 8 Q8IVL6,P13674,Q6PK18,Q32P28 4 +EH domain [IPR000261] 0.6709478903136579 1.3742307989415945 0.1693700420306256 1.0 0.7149710874800842 5 Q9H223,Q96D71 2 +Dynamin, GTPase domain [IPR001401] 0.8043220840734048 1.370208340387232 0.1706218755165061 1.0 0.7149710874800842 3 O60313,O00429 2 +Pleckstrin homology domain [IPR001849] 0.4583461658903077 1.368994258141185 0.171001069748385 1.0 0.7149710874800842 25 O75116,P31749,P31751,O60333,O15020,P50570,Q01082 7 +Acyl-CoA oxidase, C-terminal [IPR002655] 0.9375554897898792 1.3604828966946798 0.1736771616115391 1.0 0.7149710874800842 2 Q15067 1 +Ras-associating (RA) domain [IPR000159] 0.7072647444851717 1.3302831586823105 0.1834249939056345 1.0 0.7254688603218388 4 Q96L92,Q9Y4G8 2 +Class II aldolase/adducin N-terminal [IPR001303] 0.7898164594434645 1.3131758907848414 0.1891236859574527 1.0 0.7393503870291355 3 Q9UEY8,P35611 2 +AGC-kinase, C-terminal [IPR000961] 0.5538635378787871 1.2890647022435593 0.1973755936199035 1.0 0.7534614420041934 10 P31749,P31751 2 +Potentiating neddylation domain [IPR005176] 0.7832355418367575 1.287309501660783 0.1979864330638243 1.0 0.7534614420041934 3 Q92564 1 +VHS domain [IPR002014] 0.646282806276507 1.265520014943812 0.2056849782168934 1.0 0.7634445988504767 5 Q9UJY4 1 +Kinesin-associated [IPR032405] 0.7706243707332942 1.237776034164918 0.2157991171352751 1.0 0.772510458227444 3 O60333 1 +N-acetylgalactosaminyltransferase [IPR045885] 0.7690941385435249 1.2317700193526162 0.2180350055675575 1.0 0.7730734918574161 3 Q10471,Q10472 2 +HD domain [IPR006674] 0.904113643089672 1.2300401936305243 0.218682053880999 1.0 0.7730734918574161 2 Q7Z4H3 1 +HD/PDEase domain [IPR003607] 0.904113643089672 1.2300401936305243 0.218682053880999 1.0 0.7730734918574161 2 Q7Z4H3 1 +EXPERA domain [IPR033118] 0.9026339153595744 1.224289831156647 0.2208429116374859 1.0 0.7743129065559751 2 Q15125 1 +RBM3/CIRBP, RNA recognition motif [IPR034278] 0.9023379698135552 1.2231400297637656 0.2212768116249199 1.0 0.7743129065559751 2 P98179 1 +ERM family, FERM domain C-lobe [IPR041789] 0.6758933909543849 1.1994282806875558 0.2303614564510954 1.0 0.7822100090252443 4 P15311 1 +FAD-binding domain, PCMH-type [IPR016166] 0.8913879846108332 1.1806657745078624 0.2377355229255431 1.0 0.7828264918813274 2 Q15392 1 +FAD linked oxidase, N-terminal [IPR006094] 0.8913879846108332 1.1806657745078624 0.2377355229255431 1.0 0.7828264918813274 2 Q15392 1 +Zinc finger, RanBP2-type [IPR001876] 0.5448280541146457 1.1594264150712617 0.2462824147585074 1.0 0.7927274314506346 9 Q92804,P98175,Q01844,P35637 4 +MCM OB domain [IPR033762] 0.5796766122654664 1.13703945625699 0.2555217917010539 1.0 0.8055019686774856 6 P33993,P33991,P25205 3 +MCM N-terminal domain [IPR027925] 0.5796766122654664 1.13703945625699 0.2555217917010539 1.0 0.8055019686774856 6 P33993,P33991,P25205 3 +MCM, AAA-lid domain [IPR041562] 0.5796766122654664 1.13703945625699 0.2555217917010539 1.0 0.8055019686774856 6 P33993,P33991,P25205 3 +MCM domain [IPR001208] 0.5796766122654664 1.13703945625699 0.2555217917010539 1.0 0.8055019686774856 6 P33993,P33991,P25205 3 +Ataxin-2, C-terminal [IPR009818] 0.6587721838854574 1.1281103804831203 0.2592733057559475 1.0 0.8099760949471787 4 Q9BPZ3 1 +Phox homology [IPR001683] 0.4899935827503457 1.11023746900595 0.2668967107007891 1.0 0.8148616388652412 12 Q9Y5X3,O60749,Q9Y2I1,Q9UNH7 4 +Ubiquitin-like domain [IPR000626] 0.4693395127576097 1.098139026189446 0.272143786300542 1.0 0.8199965613422445 15 P46379 1 +Lamin tail domain [IPR001322] 0.7332741267021897 1.0916534412427914 0.2749854569273924 1.0 0.8249368858535133 3 P02545,Q03252 2 +Sorting nexin Vps5-like, C-terminal [IPR015404] 0.6473209208029599 1.0805200709699498 0.2799106539733773 1.0 0.8315967760672996 4 Q9UNH7,Q9Y5X3 2 +Extracellular Endonuclease, subunit A [IPR020821] 0.7264052777091938 1.0649328418320718 0.2869063218460543 1.0 0.8395973243562413 3 O94919 1 +DNA/RNA non-specific endonuclease [IPR001604] 0.7264052777091938 1.0649328418320718 0.2869063218460543 1.0 0.8395973243562413 3 O94919 1 +Glycosyltransferase 2-like [IPR001173] 0.5995466132522094 1.059472152467511 0.2893848050785841 1.0 0.8406952061024198 5 Q10471,Q10472 2 +Complex 1 LYR protein domain [IPR008011] 0.719360568383643 1.0375960510406907 0.2994581571691208 1.0 0.8450966398637766 3 Q9NU23,P56556 2 +Pleckstrin homology domain 9 [IPR041681] 0.8517312814442155 1.028302326983879 0.3038076368077007 1.0 0.8509161434120761 2 Q01082 1 +Pleckstrin homology domain, spectrin-type [IPR001605] 0.8517312814442155 1.028302326983879 0.3038076368077007 1.0 0.8509161434120761 2 Q01082 1 +SUN domain [IPR012919] 0.7105374050199035 1.0034684211584606 0.3156349059903693 1.0 0.8565903053425954 3 O94901 1 +SPRY-associated [IPR006574] 0.7057430432208404 0.9849814707456483 0.3246331726170444 1.0 0.8689406069317847 3 Q12899,P19474 2 +Ricin B, lectin domain [IPR000772] 0.5803305688712318 0.9752156483383004 0.3294533015545682 1.0 0.8734360883363652 5 Q9UBG0,Q10471,Q10472 3 +Fatty acid hydroxylase [IPR006694] 0.8271678011245949 0.9355350749011871 0.3495126161378121 1.0 0.8734360883363652 2 Q15800 1 +Exportin-2, central domain [IPR013713] 0.6923902221629207 0.9337371795445834 0.3504394814851337 1.0 0.8734360883363652 3 O95373 1 +AP complex, mu/sigma subunit [IPR022775] 0.5328752006165591 0.9187530052418172 0.3582247782939882 1.0 0.8734360883363652 6 Q9Y2T2 1 +Fragile X-related 1 protein, C-terminal core [IPR022034] 0.6865008880994583 0.9112632098962014 0.3621567060231196 1.0 0.8734360883363652 3 P51116,Q06787 2 +Synaptic functional regulator FMRP, KH0 domain [IPR040472] 0.6865008880994583 0.9112632098962014 0.3621567060231196 1.0 0.8734360883363652 3 P51116,Q06787 2 +Fxr1, tudor domain [IPR041560] 0.6865008880994583 0.9112632098962014 0.3621567060231196 1.0 0.8734360883363652 3 P51116,Q06787 2 +Agenet-like domain [IPR008395] 0.6865008880994583 0.9112632098962014 0.3621567060231196 1.0 0.8734360883363652 3 P51116,Q06787 2 +Peptidase M16, C-terminal [IPR007863] 0.5199713915367279 0.9076905673108124 0.3640417289656645 1.0 0.8734360883363652 7 P22695,Q5JRX3 2 +Peptidase M16, N-terminal [IPR011765] 0.5199713915367279 0.9076905673108124 0.3640417289656645 1.0 0.8734360883363652 7 P22695,Q5JRX3 2 +MENTAL domain [IPR019498] 0.8185853802900287 0.9035034792832816 0.3662587425156429 1.0 0.8734360883363652 2 Q14849 1 +Saposin B type domain [IPR008139] 0.8150340337377943 0.8903145485967374 0.3732970113363449 1.0 0.8744303579339661 2 P07602 1 +Syntaxin, N-terminal domain [IPR006011] 0.6776198934280688 0.8775400365178179 0.3801933826254493 1.0 0.876655364639531 3 O15400,Q13277 2 +Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337] 0.8108907960935208 0.8749786513954669 0.3815855218026578 1.0 0.8769159368653917 2 O60506 1 +TRIAD supradomain [IPR044066] 0.8088191772713842 0.86733204922752 0.3857601012661633 1.0 0.878677983620551 2 Q9UBS8 1 +IBR domain [IPR002867] 0.8088191772713842 0.86733204922752 0.3857601012661633 1.0 0.878677983620551 2 Q9UBS8 1 +ATPase family AAA domain-containing protein 3, N-terminal [IPR021911] 0.8082272861793453 0.8651499779465964 0.3869564765701208 1.0 0.8797363058760572 2 Q5T9A4 1 +KHDRBS, Qua1 domain [IPR032571] 0.8061556673572083 0.8575222249154058 0.3911563374144329 1.0 0.8823714033771215 2 O75525 1 +Sam68, tyrosine-rich domain [IPR032335] 0.8061556673572083 0.8575222249154058 0.3911563374144329 1.0 0.8823714033771215 2 O75525 1 +CTP synthase GATase domain [IPR033828] 0.8058597218111889 0.8564337632965269 0.3917578958091612 1.0 0.8823714033771215 2 Q9NRF8 1 +CTP synthase, N-terminal [IPR017456] 0.8058597218111889 0.8564337632965269 0.3917578958091612 1.0 0.8823714033771215 2 Q9NRF8 1 +GTPase effector domain [IPR020850] 0.8040840485350718 0.8499094698178375 0.3953754202266673 1.0 0.8823714033771215 2 O00429 1 +Dynamin GTPase effector [IPR003130] 0.8040840485350718 0.8499094698178375 0.3953754202266673 1.0 0.8823714033771215 2 O00429 1 +Dynamin stalk domain [IPR000375] 0.8040840485350718 0.8499094698178375 0.3953754202266673 1.0 0.8823714033771215 2 O00429 1 +Rpn11/EIF3F, C-terminal [IPR024969] 0.587434056763667 0.8348521994493638 0.4038009312019603 1.0 0.8903591097795986 4 O00487,P51665 2 +Marvel domain [IPR008253] 0.7960935187925444 0.8206919852529712 0.4118217371886827 1.0 0.8903591097795986 2 O43760 1 +Tyrosine-specific protein phosphatase, PTPase domain [IPR000242] 0.5783628641236882 0.7984013672896644 0.4246376100835132 1.0 0.8950439314756233 4 P10586 1 +Target SNARE coiled-coil homology domain [IPR000727] 0.4622680176537015 0.7914250477710945 0.4286959982246765 1.0 0.8978510931545008 10 O43752,O95721,Q13277 3 +SUN coiled coil domain 2 [IPR040994] 0.7863273157738999 0.78531659690185 0.4322679672197951 1.0 0.8978510931545008 2 O94901 1 +SET domain [IPR001214] 0.4822188257792394 0.7765513542698295 0.4374235113265272 1.0 0.9002900009405035 8 Q03164 1 +FAD dependent oxidoreductase [IPR006076] 0.5723732650040474 0.7744890596556493 0.438641635404414 1.0 0.9004084862837421 4 P43304 1 +MoaB/Mog domain [IPR001453] 0.7801124593074897 0.7630110574076168 0.4454568014622508 1.0 0.9035959917828116 2 Q8NFF5 1 +Formin, GTPase-binding domain [IPR010473] 0.6435760805210156 0.7505453307675494 0.452926332912287 1.0 0.9035959917828116 3 Q9NSV4,Q27J81 2 +Formin, FH3 domain [IPR010472] 0.6435760805210156 0.7505453307675494 0.452926332912287 1.0 0.9035959917828116 3 Q9NSV4,Q27J81 2 +Far upstream element-binding protein, C-terminal [IPR015096] 0.7721219295649628 0.7345849696018038 0.4625922945637641 1.0 0.9132723411988478 2 Q96AE4 1 +Formin, FH2 domain [IPR015425] 0.5601417672370549 0.7260902364446745 0.4677834540505916 1.0 0.9140221620665756 4 Q9NSV4,Q27J81 2 +Rho GTPase-binding/formin homology 3 (GBD/FH3) domain [IPR014768] 0.5601417672370549 0.7260902364446745 0.4677834540505916 1.0 0.9140221620665756 4 Q9NSV4,Q27J81 2 +CNNM, transmembrane domain [IPR002550] 0.7676827463746698 0.7189220415577485 0.4721889547863378 1.0 0.9184224913391772 2 Q6P4Q7 1 +Ion transporter-like, CBS domain [IPR044751] 0.7676827463746698 0.7189220415577485 0.4721889547863378 1.0 0.9184224913391772 2 Q6P4Q7 1 +RNA recognition motif domain, eukaryote [IPR003954] 0.4133049502735877 0.7039683801117067 0.4814524653256056 1.0 0.9197868398230266 14 Q14011,P38159,Q9UHX1 3 +Ribosomal S6 kinase, N-terminal catalytic domain [IPR041906] 0.7611719443622403 0.6961257886688488 0.4863500575484782 1.0 0.9197868398230266 2 Q15418 1 +OCRE domain [IPR041591] 0.6268657702005775 0.6898583339730279 0.4902832802698575 1.0 0.9197868398230266 3 P98175 1 +Polyadenylate-binding protein/Hyperplastic disc protein [IPR002004] 0.6238944791592429 0.6792032540843784 0.4970090857533287 1.0 0.9223139551861388 3 P11940 1 +GRIP domain [IPR000237] 0.7549570878958303 0.6745702178816331 0.4999488598972201 1.0 0.9236003034245834 2 Q13439 1 +Aldehyde dehydrogenase domain [IPR015590] 0.4384729088641488 0.6653177193822706 0.5058472995118422 1.0 0.9269467991878554 10 P30837,P51648 2 +Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547] 0.7502219591595178 0.6582872503540936 0.510353569001595 1.0 0.9284318974148262 2 P13674 1 +START domain [IPR002913] 0.7372003551346588 0.6141742340605997 0.5391001978038632 1.0 0.9453410087014672 2 Q14849 1 +Peptidase M41 [IPR000642] 0.7312814442142681 0.5944646562431976 0.5522013748598091 1.0 0.9474402480397944 2 Q9Y4W6 1 +CARG-binding factor, N-terminal [IPR012956] 0.7274341521160141 0.5817743301782206 0.5607186967987452 1.0 0.9538483321010028 2 Q99729 1 +Myosin head, motor domain [IPR001609] 0.4301612011000568 0.5707507887625234 0.568168585638583 1.0 0.9607963991101054 9 P35579,P35580,Q7Z406 3 +RBM1CTR [IPR012604] 0.7215152411956238 0.5624435868668285 0.573813829212479 1.0 0.9623804887742992 2 P38159 1 +U-box domain [IPR003613] 0.445402838399044 0.528112039930752 0.5974215747602325 1.0 0.9741446944925692 6 O95155 1 +SAM-dependent methyltransferase RsmB/NOP2-type [IPR001678] 0.5787435369579625 0.5234590698483411 0.6006548269897884 1.0 0.9741446944925692 3 Q96P11 1 +Damage-control phosphatase ARMT1-like, metal-binding domain [IPR002791] 0.6954720331459054 0.4803939518380355 0.6309472941372665 1.0 0.9765572697770588 2 Q9NVE7 1 +ROCK, Rho binding domain [IPR015008] 0.6889612311334757 0.4607101509576802 0.6450065712237312 1.0 0.9765572697770588 2 O75116 1 +Fragile X-related 1 protein, C-terminal region 1 [IPR032172] 0.6862977212192998 0.4527599176747609 0.6507216289004691 1.0 0.9765572697770588 2 P51116 1 +EB1, C-terminal [IPR004953] 0.6827463746670656 0.4422541215343804 0.6583053259749272 1.0 0.9765572697770588 2 Q15555 1 +CBS domain [IPR000644] 0.4239392826600673 0.4398169923824647 0.6600696595412641 1.0 0.9765572697770588 6 Q6P4Q7 1 +Proteasome component (PCI) domain [IPR000717] 0.3402618903722779 0.4343410392745229 0.6640408064536252 1.0 0.9765572697770588 19 Q99627,O00231,P61201,Q9UBW8,O43242,Q9UNM6,Q9Y262,Q5JVF3,Q13098,Q9BT78 10 +UAS [IPR006577] 0.5361160449970508 0.3900210932841763 0.6965209494499742 1.0 0.9765572697770588 3 Q9UNN5,O94888 2 +tRNA-binding domain [IPR002547] 0.663213968629777 0.3864918695489473 0.6991324228957625 1.0 0.9765572697770588 2 Q12904 1 +DnaJ domain [IPR001623] 0.3452773400390929 0.3818595087153002 0.7025655757640901 1.0 0.9765572697770588 17 O60884,Q13217,O75937,Q96KC8,Q99615,Q5F1R6,Q99543,Q8WXX5 8 +Septin-type guanine nucleotide-binding (G) domain [IPR030379] 0.408656824530983 0.3798189900549192 0.7040797848587546 1.0 0.9765572697770588 6 Q15019,Q14141 2 +CRIB domain [IPR000095] 0.6540396567031714 0.3615437243535337 0.7176930249296656 1.0 0.9765572697770588 2 Q13177 1 +p21 activated kinase binding domain [IPR033923] 0.6540396567031714 0.3615437243535337 0.7176930249296656 1.0 0.9765572697770588 2 Q13177 1 +Glutamine amidotransferase [IPR017926] 0.4585285393472551 0.3598865772614551 0.7189319552252156 1.0 0.9765572697770588 4 Q9NRF8 1 +Amine oxidase [IPR002937] 0.4563221794492015 0.3529395837938819 0.7241337344274146 1.0 0.9765572697770588 4 Q8NB78,O60341,P50336 3 +JAB1/MPN/MOV34 metalloenzyme domain [IPR000555] 0.3864588601770056 0.3376321906457809 0.7356403806430007 1.0 0.9765572697770588 8 O00303,P51665,O15372,Q92905,O00487 5 +HR1 rho-binding domain [IPR011072] 0.4191308105119334 0.3292122439540255 0.7419952689658285 1.0 0.9765572697770588 5 Q16513,Q5T0N5,O75116 3 +ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain [IPR004100] 0.4478843219026858 0.3268865840908463 0.7437536685147121 1.0 0.9765572697770588 4 P06576 1 +ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain [IPR000194] 0.4478843219026858 0.3268865840908463 0.7437536685147121 1.0 0.9765572697770588 4 P06576 1 +Protein-tyrosine phosphatase, catalytic [IPR003595] 0.3812406635894891 0.3164824078807283 0.7516363759698419 1.0 0.9765572697770588 8 P10586 1 +Proteasomal ATPase OB C-terminal domain [IPR032501] 0.4129146919431157 0.3086769038654542 0.7575673144725348 1.0 0.9765572697770588 5 P62191,P62195,P62333,P17980 4 +Tudor domain [IPR002999] 0.3780779001681721 0.3038604283677 0.7612342267239809 1.0 0.9765572697770588 8 Q14739,Q9Y2W6 2 +PABP, RNA recognition motif 2 [IPR045305] 0.631251849659668 0.3032784546711575 0.7616776641424075 1.0 0.9765572697770588 2 P11940 1 +14-3-3 domain [IPR023410] 0.3869629629629664 0.2995852009527869 0.7644935739050567 1.0 0.9765572697770588 6 Q04917,P31946,P62258,P63104,P61981 5 +26S proteasome regulatory subunit Rpn7, N-terminal [IPR045135] 0.6241491565551992 0.2862503335749545 0.7746863951902947 1.0 0.9765572697770588 2 Q13098 1 +L27-2 [IPR015132] 0.6235572654631603 0.2848564305488157 0.775754136990001 1.0 0.9765572697770588 2 Q8NI35 1 +Ubiquitin-associated domain [IPR015940] 0.3333839159270845 0.2837162958595942 0.7766278054019164 1.0 0.9765572697770588 16 Q9UMX0,Q13501,Q9Y5A7,Q04323 4 +cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain [IPR003117] 0.6229653743711212 0.2834664212033291 0.7768193184672998 1.0 0.9765572697770588 2 P10644 1 +Fibronectin type II domain [IPR000562] 0.4966952434424564 0.2821699840787982 0.7778131727733697 1.0 0.9765572697770588 3 Q9UBV2 1 +MPN domain [IPR037518] 0.3578711547321726 0.2742936418554888 0.7838589702757064 1.0 0.9765572697770588 10 O00303,P51665,O15372,Q92905,O00487 5 +Coatomer, gamma subunit, appendage, Ig-like subdomain [IPR013040] 0.6143829535365548 0.2637527111985298 0.7919704755239125 1.0 0.9765572697770588 2 Q9UBF2 1 +Coatomer subunit gamma, C-terminal [IPR032154] 0.6143829535365548 0.2637527111985298 0.7919704755239125 1.0 0.9765572697770588 2 Q9UBF2 1 +4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896] 0.4801657785672114 0.2421894914153882 0.8086333373436985 1.0 0.9765572697770588 3 P61221,P21912 2 +MIF4G-like, type 3 [IPR003890] 0.3617745575998708 0.2413321839281822 0.8092976687403566 1.0 0.9765572697770588 8 Q9H074 1 +Helicase/UvrB, N-terminal [IPR006935] 0.4763173475429401 0.2333606616999712 0.8154813573505411 1.0 0.9765572697770588 3 P19447,Q92900 2 +Ubiquitin system component CUE [IPR003892] 0.4653641207815475 0.2092541782401271 0.8342498203364714 1.0 0.9765572697770588 3 Q9H1I8,Q9Y679 2 +BAT2, N-terminal [IPR009738] 0.4567791592658496 0.1914361974536589 0.8481838629780865 1.0 0.9765572697770588 3 P48634,Q9Y520 2 +Choline/carnitine acyltransferase domain [IPR039551] 0.5788694880142116 0.1912432352868524 0.8483350318161604 1.0 0.9765572697770588 2 P23786 1 +Importin-alpha, importin-beta-binding domain [IPR002652] 0.3729265402843499 0.1896812876005828 0.8495588849304507 1.0 0.9765572697770588 5 P52292,O00505,O60684,O00629 4 +Initiation factor eIF-4 gamma, MA3 [IPR003891] 0.3509737679979992 0.1819975478253252 0.8555846503161295 1.0 0.9765572697770588 6 Q9HCG8 1 +Man1/Src1, C-terminal [IPR018996] 0.5652559928973134 0.1674220315428149 0.8670379911628399 1.0 0.9765572697770588 2 Q9Y2U8 1 +SMCs flexible hinge [IPR010935] 0.3609057649514972 0.1588144201925726 0.8738150873358237 1.0 0.9765572697770588 5 Q9UQE7 1 +Tubulin/FtsZ, GTPase domain [IPR003008] 0.3407407407407445 0.1526431394111993 0.8786797032852867 1.0 0.9765572697770588 6 P68371,P07437,Q13509,Q13885,Q9BUF5 5 +Tubulin/FtsZ, 2-layer sandwich domain [IPR018316] 0.3407407407407445 0.1526431394111993 0.8786797032852867 1.0 0.9765572697770588 6 P68371,P07437,Q13509,Q13885,Q9BUF5 5 +Domain of unknown function DUF4749 [IPR031847] 0.5528262799644932 0.1476110924703645 0.8826497004813658 1.0 0.9765572697770588 2 O00151 1 +Glycosyl transferase, family 1 [IPR001296] 0.4209149004525413 0.1274921415422713 0.8985508925694754 1.0 0.9765572697770588 3 Q2TAA5 1 +FCP1 homology domain [IPR004274] 0.5371411660254584 0.1252248517977262 0.9003455432118277 1.0 0.9765572697770588 2 Q8WVY7 1 +Elp3/MiaB/NifB [IPR006638] 0.5356614382953606 0.1232613139645224 0.901900174152798 1.0 0.9765572697770588 2 Q5VV42 1 +Radical SAM [IPR007197] 0.5356614382953606 0.1232613139645224 0.901900174152798 1.0 0.9765572697770588 2 Q5VV42 1 +Zinc finger, GRF-type [IPR010666] 0.5332938739272044 0.1201721797945457 0.9043467553495736 1.0 0.9773008519380216 2 Q13472 1 +YTH domain [IPR007275] 0.3583912106694336 0.1099231874950187 0.9124702930144004 1.0 0.9773008519380216 4 Q9H6S0,Q7Z739 2 +Domain of unknown function DUF1747 [IPR013719] 0.5134655223438961 0.0967863094060458 0.9228960963982272 1.0 0.9804438899380706 2 Q08945 1 +THUMP domain [IPR004114] 0.5039952648712711 0.0871315492945984 0.9305669480308598 1.0 0.9809264880318828 2 Q9NXG2 1 +SGNH hydrolase-type esterase domain [IPR013830] 0.5013317549570955 0.0845854335236755 0.932590979925964 1.0 0.9809264880318828 2 P68402 1 +Gelsolin-like domain [IPR007123] 0.3030202732829468 0.0619688456770183 0.9505876418499092 1.0 0.9889927514420132 6 Q15437 1 +B-box-type zinc finger [IPR000315] 0.3121761350190712 0.0594372056685979 0.9526038795902873 1.0 0.9899721964430628 5 P19474 1 +OTU domain [IPR003323] 0.466706126072811 0.0577373933256869 0.953957807797022 1.0 0.9899721964430628 2 Q6GQQ9 1 +Sin3, C-terminal [IPR031693] 0.4664101805267909 0.0575543175853827 0.9541036386009228 1.0 0.9899721964430628 2 O75182 1 +Histone deacetylase interacting domain [IPR013194] 0.4664101805267909 0.0575543175853827 0.9541036386009228 1.0 0.9899721964430628 2 O75182 1 +NECAP, PHear domain [IPR012466] 0.4640426161586346 0.056115667897493 0.9552496624285922 1.0 0.9904804159715318 2 Q8NC96 1 +FCH domain [IPR001060] 0.4631547795205765 0.0555879633597163 0.9556700535261556 1.0 0.9904804159715318 2 Q5T0N5 1 +F-BAR domain [IPR031160] 0.4631547795205765 0.0555879633597163 0.9556700535261556 1.0 0.9904804159715318 2 Q5T0N5 1 +Peptidase S8/S53 domain [IPR000209] 0.4483575022195996 0.0476950926615689 0.9619592451425748 1.0 0.9930360017448054 2 P29144 1 +DNA mismatch repair protein MutS-like, N-terminal [IPR007695] 0.3472468916518666 0.0473956159747511 0.9621979230409584 1.0 0.9930360017448054 3 P43246,P52701 2 +DNA mismatch repair protein MutS, C-terminal [IPR000432] 0.3472468916518666 0.0473956159747511 0.9621979230409584 1.0 0.9930360017448054 3 P43246,P52701 2 +DNA mismatch repair protein MutS, connector domain [IPR007860] 0.3472468916518666 0.0473956159747511 0.9621979230409584 1.0 0.9930360017448054 3 P43246,P52701 2 +DNA mismatch repair protein MutS, core [IPR007696] 0.3472468916518666 0.0473956159747511 0.9621979230409584 1.0 0.9930360017448054 3 P43246,P52701 2 +DEUBAD domain [IPR044867] 0.4246818585380352 0.0382199936068418 0.969512279948282 1.0 0.9947641229131874 2 Q6P4R8 1 +Serine/arginine-rich splicing factor SRSF4-like, RNA recognition motif 1 [IPR035585] 0.3989345960343365 0.0314449243920358 0.974914714365217 1.0 0.9947641229131874 2 Q08170 1 +CHD subfamily II, SANT-like domain [IPR009462] 0.3977508138502598 0.0312051977497274 0.9751058947296868 1.0 0.9947641229131874 2 Q12873 1 +CHD, C-terminal 2 [IPR012957] 0.3977508138502598 0.0312051977497274 0.9751058947296868 1.0 0.9947641229131874 2 Q12873 1 +CHD, N-terminal [IPR012958] 0.3977508138502598 0.0312051977497274 0.9751058947296868 1.0 0.9947641229131874 2 Q12873 1 +Domain of unknown function DUF1087 [IPR009463] 0.3977508138502598 0.0312051977497274 0.9751058947296868 1.0 0.9947641229131874 2 Q12873 1 +TATA-binding protein interacting (TIP20) [IPR013932] 0.3956791950281224 0.0307989521226123 0.9754298761099188 1.0 0.9947641229131874 2 O75155 1 +ZU5 domain [IPR000906] 0.3838413731873432 0.0287789373967848 0.9770408994439366 1.0 0.9947641229131874 2 Q07157 1 +Extended synaptotagmin, C2A domain [IPR037733] 0.3805859721811256 0.0283059021610986 0.9774181732436154 1.0 0.9947641229131874 2 A0FGR8 1 +Synaptotagmin, SMP domain [IPR039010] 0.3805859721811256 0.0283059021610986 0.9774181732436154 1.0 0.9947641229131874 2 A0FGR8 1 +Extended synaptotagmin, C2B domain [IPR037749] 0.3805859721811256 0.0283059021610986 0.9774181732436154 1.0 0.9947641229131874 2 A0FGR8 1 +Extended synaptotagmin, C-terminal C2 domain [IPR037752] 0.3805859721811256 0.0283059021610986 0.9774181732436154 1.0 0.9947641229131874 2 A0FGR8 1 +Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468] 0.3805859721811256 0.0283059021610986 0.9774181732436154 1.0 0.9947641229131874 2 A0FGR8 1 +tRNA synthetases class I, catalytic domain [IPR032678] 0.3794021899970495 0.0281419791519046 0.9775489127983288 1.0 0.9947641229131874 2 P49589 1 +Cyclin-like [IPR013763] 0.2934557299378032 0.0278219074849185 0.9778041930782676 1.0 0.9947641229131874 4 O95067,P20248,Q00403 3 +MRG domain [IPR026541] 0.3649008582420934 0.0264496899122258 0.9788986611769032 1.0 0.9947641229131874 2 Q9UBU8 1 +EF hand associated, type-1 [IPR013566] 0.3551346552234472 0.0255941438188427 0.9795810570971076 1.0 0.9947641229131874 2 Q8IXI1 1 +MIRO domain [IPR020860] 0.3551346552234472 0.0255941438188427 0.9795810570971076 1.0 0.9947641229131874 2 Q8IXI1 1 +EF hand associated, type-2 [IPR013567] 0.3551346552234472 0.0255941438188427 0.9795810570971076 1.0 0.9947641229131874 2 Q8IXI1 1 +SWIRM domain [IPR007526] 0.2904945217648749 0.0254694364682374 0.9796805267406729 1.0 0.9947641229131874 4 Q8NB78,O60341,Q8TAQ2 3 +NAD-dependent epimerase/dehydratase [IPR001509] 0.3370819769162554 0.0244747135844243 0.9804739533084692 1.0 0.9947641229131874 2 Q13630 1 +Zinc finger, CW-type [IPR011124] 0.2974252737496388 0.0233446896990798 0.98137532419008 1.0 0.9947641229131874 2 Q8NB78 1 +Cyclin, N-terminal [IPR006671] 0.2933688573120138 0.0232780043850806 0.981428516917612 1.0 0.9947641229131874 3 O95067,P20248 2 +Cyclin, C-terminal domain [IPR004367] 0.2933688573120138 0.0232780043850806 0.981428516917612 1.0 0.9947641229131874 3 O95067,P20248 2 diff --git a/interpro_domain/selections.json b/interpro_domain/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..59ade448b608028ea42a34306b4eb9f6e319f062 --- /dev/null +++ b/interpro_domain/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, SH3 domain [IPR035724]", "116kDa U5 small nuclear ribonucleoprotein component, C-terminal [IPR035655]", "116kDa U5 small nuclear ribonucleoprotein component, N-terminal [IPR031950]", "14-3-3 domain [IPR023410]", "18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23, C-terminal [IPR022238]", "2-oxoacid dehydrogenase acyltransferase, catalytic domain [IPR001078]", "2-oxoglutarate dehydrogenase E1 component, N-terminal domain [IPR032106]", "26S proteasome non-ATPase regulatory subunit RPN1, C-terminal [IPR041433]", "26S proteasome regulatory subunit RPN2, C-terminal [IPR040623]", "26S proteasome regulatory subunit RPN5, C-terminal domain [IPR040896]", "26S proteasome regulatory subunit Rpn6, N-terminal [IPR040773]", "26S proteasome regulatory subunit Rpn7, N-terminal [IPR045135]", "26S proteasome regulatory subunit, C-terminal [IPR013586]", "2Fe-2S ferredoxin-type iron-sulfur binding domain [IPR001041]", "3'-5' exonuclease domain [IPR002562]", "3-beta hydroxysteroid dehydrogenase/isomerase [IPR002225]", "3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108]", "3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176]", "3-hydroxyisobutyrate dehydrogenase, NAD-binding domain [IPR029154]", "3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal [IPR001104]", "4'-phosphopantetheinyl transferase domain [IPR008278]", "40S ribosomal protein S11, N-terminal [IPR032440]", "40S ribosomal protein S4, C-terminal domain [IPR032277]", "40S ribosomal protein SA, C-terminal domain [IPR032281]", "4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896]", "5'-3' exoribonuclease 1, SH3-like domain [IPR041385]", "5'-AMP-activated protein kinase alpha 1 catalytic subunit, C-terminal [IPR039137]", "6-phosphogluconate dehydrogenase, C-terminal [IPR006114]", "6-phosphogluconate dehydrogenase, NADP-binding [IPR006115]", "6-phosphogluconolactonase, DevB-type [IPR005900]", "60S ribosomal protein L10P, insertion domain [IPR040637]", "60S ribosomal protein L4, C-terminal domain [IPR025755]", "6S proteasome subunit Rpn6, C-terminal helix domain [IPR040780]", "A kinase-anchoring protein AKAP5 and AKAP12, calmodulin (CaM)-binding motif [IPR001573]", "AAA ATPase, AAA+ lid domain [IPR041569]", "AAA lid domain [IPR041083]", "AAA+ ATPase domain [IPR003593]", "AAR2, C-terminal [IPR033648]", "AAR2, N-terminal [IPR033647]", "AARP2CN [IPR012948]", "AATF leucine zipper-containing domain [IPR025160]", "ABC transporter type 1, transmembrane domain [IPR011527]", "ABC transporter-like, ATP-binding domain [IPR003439]", "ABC-transporter extension domain [IPR032781]", "ABC-type uncharacterised transport system [IPR019196]", "ABC1 atypical kinase-like domain [IPR004147]", "ABT1/ESF2, RNA recognition motif [IPR034353]", "ADAM, cysteine-rich domain [IPR006586]", "ADAM10/ADAM17 catalytic domain [IPR034025]", "ADAM17, membrane-proximal domain [IPR032029]", "ADAR1, first double-stranded RNA binding domain [IPR044456]", "ADAR1, third double-stranded RNA binding domain [IPR044457]", "ADCK3-like domain [IPR034646]", "ADD domain [IPR025766]", "ADNP, zinc finger domain [IPR045762]", "AGC-kinase, C-terminal [IPR000961]", "AIMP2, lysyl-tRNA synthetase binding domain [IPR031889]", "AIMP2, thioredoxin-like domain [IPR041503]", "ALG11 mannosyltransferase, N-terminal [IPR031814]", "ALIX V-shaped domain [IPR025304]", "AMP-binding enzyme, C-terminal domain [IPR025110]", "AMP-dependent synthetase/ligase [IPR000873]", "AMPK, C-terminal adenylate sensor domain [IPR032270]", "AP complex, mu/sigma subunit [IPR022775]", "AP-2 complex subunit mu, N-terminal [IPR043532]", "AP-3 complex subunit beta 1, serine-rich domain [IPR029394]", "AP-3 complex subunit beta, C-terminal domain [IPR029390]", "AP-3 complex subunit delta domain, metazoa [IPR010474]", "AP180 N-terminal homology (ANTH) domain [IPR011417]", "APC10/DOC domain [IPR004939]", "ARHGEF1-like, PH domain [IPR041020]", "ARHGEF2, PH domain [IPR037806]", "ARID DNA-binding domain [IPR001606]", "ARMET, C-terminal [IPR019345]", "ARMET, N-terminal [IPR045332]", "ATP synthase, F1 complex, alpha subunit nucleotide-binding domain [IPR033732]", "ATP synthase, alpha subunit, C-terminal [IPR000793]", "ATP-citrate lyase/succinyl-CoA ligase [IPR005811]", "ATP-citrate synthase, citrate-binding domain [IPR032263]", "ATP-cone domain [IPR005144]", "ATP-dependent DNA helicase RecQ, zinc-binding domain [IPR032284]", "ATP-dependent RNA helicase Ski2, C-terminal [IPR012961]", "ATP-dependent RNA helicase eIF4A, DEAD-box helicase domain [IPR044728]", "ATP-dependent helicase, C-terminal [IPR006555]", "ATP-grasp fold [IPR011761]", "ATP-grasp fold, succinyl-CoA synthetase-type [IPR013650]", "ATP-sulfurylase PUA-like domain [IPR025980]", "ATP:guanido phosphotransferase, N-terminal [IPR022413]", "ATP:guanido phosphotransferase, catalytic domain [IPR022414]", "ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]", "ATPase, AAA-type, core [IPR003959]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain [IPR004100]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain [IPR000194]", "ATPase, V1 complex, subunit H, C-terminal [IPR011987]", "ATPase, dynein-related, AAA domain [IPR011704]", "ATPsynthase alpha/beta subunit, N-terminal extension [IPR031686]", "ATRX, ADD domain [IPR041430]", "AWS domain [IPR006560]", "Abscisic acid G-protein coupled receptor-like domain [IPR025969]", "Acetyl-CoA carboxylase [IPR034733]", "Acetyl-CoA carboxylase, central domain [IPR013537]", "Acetyl-coA carboxylase zinc finger domain [IPR041010]", "Acetyl-coenzyme A carboxyltransferase, C-terminal [IPR011763]", "Acetyl-coenzyme A carboxyltransferase, N-terminal [IPR011762]", "Acetyl-coenzyme A synthetase, N-terminal domain [IPR032387]", "Acid ceramidase, N-terminal [IPR029130]", "Acinus, RNA recognition motif [IPR034257]", "Aconitase A, swivel domain [IPR044137]", "Aconitase A/isopropylmalate dehydratase small subunit, swivel domain [IPR000573]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain [IPR001030]", "Actin-depolymerising factor homology domain [IPR002108]", "Activating signal cointegrator 1 complex subunit 2, CUE domain [IPR041800]", "Activator of Hsp90 ATPase, N-terminal [IPR015310]", "Acyl transferase [IPR014043]", "Acyl-CoA dehydrogenase family member 10/11, N-terminal [IPR041726]", "Acyl-CoA dehydrogenase/oxidase C-terminal [IPR009075]", "Acyl-CoA dehydrogenase/oxidase, N-terminal [IPR013786]", "Acyl-CoA oxidase, C-terminal [IPR002655]", "Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091]", "Acyl-CoA-binding protein, ACBP [IPR000582]", "Acyl-coenzyme A oxidase, N-terminal [IPR029320]", "Acylamino-acid-releasing enzyme, N-terminal domain [IPR045550]", "Acylglycerol kinase, C-terminal [IPR045579]", "Acyltransferase, C-terminal domain [IPR032098]", "Adaptor protein Cbl, EF hand-like [IPR014741]", "Adaptor protein Cbl, N-terminal helical [IPR003153]", "Adaptor protein Cbl, PTB domain [IPR024159]", "Adaptor protein Cbl, SH2-like domain [IPR014742]", "Adenomatous polyposis coli protein basic domain [IPR009234]", "Adenomatous polyposis coli, N-terminal dimerisation domain [IPR032038]", "Adenosine deaminase domain [IPR001365]", "Adenosine deaminase/editase [IPR002466]", "Adenylate cyclase-associated CAP, C-terminal [IPR013912]", "Adenylate cyclase-associated CAP, N-terminal [IPR013992]", "Adenylate kinase, active site lid domain [IPR007862]", "Adenylosuccinate lyase C-terminal [IPR019468]", "Afadin, cargo binding domain [IPR037977]", "Agenet-like domain [IPR008395]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal [IPR007886]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain [IPR007698]", "Alanine racemase, N-terminal [IPR001608]", "Alanyl-tRNA synthetase, class IIc, N-terminal [IPR018164]", "Alanyl-tRNA synthetase, class IIc, core domain [IPR018165]", "Alcohol dehydrogenase, N-terminal [IPR013154]", "Alcohol dehydrogenase-like, C-terminal [IPR013149]", "Aldehyde dehydrogenase domain [IPR015590]", "Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant [IPR000866]", "Alpha Spectrin, SH3 domain [IPR035825]", "Alpha crystallin/Hsp20 domain [IPR002068]", "Alpha galactosidase A, C-terminal beta-sandwich domain [IPR035373]", "Alpha-2-macroglobulin RAP, C-terminal [IPR010483]", "Alpha-2-macroglobulin RAP, domain 2 [IPR038001]", "Alpha-2-macroglobulin RAP, domain 3 [IPR037999]", "Alpha-2-macroglobulin [IPR001599]", "Alpha-2-macroglobulin receptor-associated protein, domain 1 [IPR009066]", "Alpha-2-macroglobulin, TED domain [IPR041813]", "Alpha-2-macroglobulin, bait region domain [IPR011625]", "Alpha-D-phosphohexomutase, C-terminal [IPR005843]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain I [IPR005844]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain II [IPR005845]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain III [IPR005846]", "Alpha-L-fucosidase, C-terminal [IPR031919]", "Alpha-N-acetylglucosaminidase, C-terminal [IPR024732]", "Alpha-N-acetylglucosaminidase, N-terminal [IPR024240]", "Alpha-N-acetylglucosaminidase, tim-barrel domain [IPR024733]", "Alpha-glycerophosphate oxidase, C-terminal [IPR031656]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like [IPR027450]", "Alpha-ketoglutarate-dependent dioxygenase FTO, C-terminal [IPR024366]", "Alpha-ketoglutarate-dependent dioxygenase FTO, catalytic domain [IPR024367]", "Alpha-macroglobulin, receptor-binding [IPR009048]", "Alpha-macroglobulin-like, TED domain [IPR011626]", "Alpha/beta hydrolase fold-1 [IPR000073]", "Amidase signature domain [IPR023631]", "Amidohydrolase-related [IPR006680]", "Amidophosphoribosyltransferase, N-terminal [IPR035584]", "Amine oxidase [IPR002937]", "Amino acid permease, N-terminal [IPR013612]", "Amino acid permease/ SLC12A domain [IPR004841]", "Amino acid transporter, transmembrane domain [IPR013057]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding [IPR045462]", "Aminoacyl-tRNA synthetase, class II (D/K/N) [IPR004364]", "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) [IPR002314]", "Aminoacyl-tRNA synthetase, class II [IPR006195]", "Aminoacyl-tRNA synthetase, class Ia [IPR002300]", "Aminoglycoside phosphotransferase [IPR002575]", "Aminomethyltransferase, folate-binding domain [IPR006222]", "Aminopeptidase N-like , N-terminal domain [IPR045357]", "Aminopeptidase P [IPR033740]", "Aminopeptidase P, N-terminal [IPR007865]", "Aminotransferase class V domain [IPR000192]", "Aminotransferase, class I/classII [IPR004839]", "Amyloidogenic glycoprotein, E2 domain [IPR024329]", "Amyloidogenic glycoprotein, amyloid-beta peptide [IPR013803]", "Amyloidogenic glycoprotein, copper-binding [IPR011178]", "Amyloidogenic glycoprotein, extracellular [IPR008154]", "Amyloidogenic glycoprotein, heparin-binding [IPR015849]", "Anaphase-promoting complex subunit 1, C-terminal [IPR041221]", "Anaphase-promoting complex subunit 2, C-terminal [IPR014786]", "Anaphase-promoting complex subunit 4, WD40 domain [IPR024977]", "Anaphase-promoting complex subunit 5 domain [IPR026000]", "Ancestral coatomer element 1, Sec16/Sec31 [IPR024298]", "Angiomotin, C-terminal [IPR024646]", "Anillin homology domain [IPR012966]", "Anillin, N-terminal domain [IPR031970]", "Anillin, PH domain [IPR037840]", "Anion-transporting ATPase-like domain [IPR025723]", "Ankyrin repeat and LEM domain-containing protein 2, LEM domain [IPR035006]", "Ankyrin, UPA domain [IPR040745]", "Ankyrin-3, death domain [IPR037971]", "Anoctamin, dimerisation domain [IPR032394]", "Anticodon-binding [IPR004154]", "Anticodon-binding domain [IPR019181]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal [IPR006190]", "ApaG domain [IPR007474]", "Apoptosis-antagonizing transcription factor, C-terminal [IPR012617]", "Archaeal primase DnaG/twinkle, TOPRIM domain [IPR034154]", "Arf GTPase activating protein [IPR001164]", "Arfaptin homology (AH) domain [IPR010504]", "Arginyl tRNA synthetase N-terminal domain [IPR005148]", "Arginyl-tRNA synthetase, catalytic core domain [IPR035684]", "Ariadne domain [IPR045840]", "Armadillo repeat-containing domain [IPR006911]", "Aromatic amino acid beta-eliminating lyase/threonine aldolase [IPR001597]", "Asn/Gln amidotransferase [IPR018027]", "Asparagine synthase [IPR001962]", "Asparagine synthase, N-terminal domain [IPR033738]", "Aspartate/glutamate/uridylate kinase [IPR001048]", "Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain [IPR006131]", "Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding [IPR006132]", "Aspartic peptidase, DDI1-type [IPR019103]", "Aspartyl beta-hydroxylase/Triadin domain [IPR007943]", "Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic [IPR006075]", "Aspartyl/asparaginy/proline hydroxylase [IPR007803]", "Ataxin 2, SM domain [IPR025852]", "Ataxin-10 domain [IPR019156]", "Ataxin-2, C-terminal [IPR009818]", "Aurora-A binding [IPR015128]", "Autophagy-related, C-terminal [IPR015412]", "B(0)AT2, solute-binding domain [IPR042934]", "B-block binding subunit of TFIIIC [IPR007309]", "B-box, C-terminal [IPR003649]", "B-box-type zinc finger [IPR000315]", "B3/B4 tRNA-binding domain [IPR005146]", "B30.2/SPRY domain [IPR001870]", "BAG domain [IPR003103]", "BAP29/BAP31, transmembrane domain [IPR040463]", "BAR domain [IPR004148]", "BAT2, N-terminal [IPR009738]", "BAZ2A/BAZ2B, bromodomain [IPR037374]", "BCAS3 domain [IPR022175]", "BCL-6 corepressor, PCGF1 binding domain [IPR032365]", "BCL-6 corepressor, non-ankyrin-repeat domain [IPR031628]", "BCNT-C domain [IPR011421]", "BCS1, N-terminal [IPR014851]", "BDHCT [IPR012532]", "BEACH domain [IPR000409]", "BEN domain [IPR018379]", "BING4, C-terminal domain [IPR012952]", "BOP1, N-terminal domain [IPR012953]", "BP28, C-terminal domain [IPR012954]", "BRCA1, serine-rich domain [IPR025994]", "BRCT domain [IPR001357]", "BRICHOS domain [IPR007084]", "BRK domain [IPR006576]", "BRO1 domain [IPR004328]", "BSD domain [IPR005607]", "BTB/Kelch-associated [IPR011705]", "BTB/POZ domain [IPR000210]", "BURAN domain [IPR045354]", "BZW1/2, W2 domain [IPR043510]", "Bacterial Ig-like, group 2 [IPR003343]", "Bacterial surface antigen (D15) [IPR000184]", "Band 3 cytoplasmic domain [IPR013769]", "Band 4.1 domain [IPR019749]", "Band 4.1, C-terminal [IPR008379]", "Band 7 domain [IPR001107]", "Band 7, C-terminal extension [IPR032435]", "Bap31/Bap29 cytoplasmic coiled-coil domain [IPR041672]", "Basic-leucine zipper domain [IPR004827]", "Beta-Casp domain [IPR022712]", "Beta-adaptin appendage, C-terminal subdomain [IPR015151]", "Beta-amyloid precursor protein C-terminal [IPR019543]", "Beta-catenin-interacting ICAT domain [IPR009428]", "Beta-catenin-like protein 1, N-terminal [IPR013180]", "Beta-galactosidase jelly roll domain [IPR025300]", "Beta-hexosaminidase, eukaryotic type, N-terminal [IPR029019]", "Beta-ketoacyl synthase, C-terminal [IPR014031]", "Beta-ketoacyl synthase, N-terminal [IPR014030]", "Beta-lactamase-related [IPR001466]", "Beta-trefoil DNA-binding domain [IPR015350]", "Bicarbonate transporter, C-terminal [IPR011531]", "Bifunctional delta 1-pyrroline-5-carboxylate synthetase, glutamate-5-kinase domain [IPR041744]", "Biliverdin reductase, catalytic [IPR015249]", "Bin3-type S-adenosyl-L-methionine binding domain [IPR024160]", "Biotin carboxylase, C-terminal [IPR005482]", "Biotin carboxylase-like, N-terminal domain [IPR005481]", "Biotin carboxylation domain [IPR011764]", "Biotin protein ligase, C-terminal [IPR003142]", "Biotin-protein ligase, N-terminal [IPR019197]", "Biotin/lipoyl attachment [IPR000089]", "Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain [IPR004143]", "Bloom syndrome protein, BDHCT-box associated domain [IPR032439]", "Bloom syndrome protein, N-terminal domain [IPR032437]", "Bms1/Tsr1-type G domain [IPR030387]", "Borealin, N-terminal [IPR018851]", "Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal [IPR018955]", "Brd8, Bromo domain [IPR037966]", "Brdt, bromodomain, repeat I [IPR043508]", "Brdt, bromodomain, repeat II [IPR043509]", "Brix domain [IPR007109]", "Bromo adjacent homology (BAH) domain [IPR001025]", "Bromodomain [IPR001487]", "Bromodomain adjacent to zinc finger domain protein 1A, bromodomain [IPR037325]", "Bromodomain protein 4, C-terminal [IPR031354]", "Brr2, N-terminal helicase PWI domain [IPR041094]", "Bud22 domain [IPR015158]", "Butyrophylin-like, SPRY domain [IPR003879]", "C-CAP/cofactor C-like domain [IPR017901]", "C-terminal associated domain of TOPRIM [IPR031660]", "C-type lectin-like [IPR001304]", "C19orf47, SAM domain [IPR040772]", "C2 DOCK-type domain [IPR027007]", "C2 domain [IPR000008]", "C2 phosphatidylinositol 3-kinase-type domain [IPR002420]", "C2CD5, C2 domain [IPR037785]", "C4-type zinc-finger of DNA polymerase delta [IPR025687]", "CAAX prenyl protease 1, N-terminal [IPR032456]", "CALCOCO1/2, zinc finger UBZ1-type [IPR041641]", "CAP Gly-rich domain [IPR000938]", "CAPN2, penta-EF hand, calcium binding motif [IPR042736]", "CARG-binding factor, N-terminal [IPR012956]", "CARP motif [IPR006599]", "CASK, SH3 domain [IPR035473]", "CBS domain [IPR000644]", "CCAAT-binding factor [IPR005612]", "CCD97-like, C-terminal [IPR040233]", "CCDC93, coiled-coil domain [IPR019159]", "CCR4-NOT transcription complex subunit 1, CAF1-binding domain [IPR032191]", "CCR4-NOT transcription complex subunit 1, HEAT repeat [IPR032194]", "CCR4-NOT transcription complex subunit 1, TTP binding domain [IPR032193]", "CCR4-NOT transcription complex subunit 1, domain 4 [IPR024557]", "CCR4-Not complex component, Not1, C-terminal [IPR007196]", "CD2-associated protein, first SH3 domain [IPR035775]", "CD2-associated protein, second SH3 domain [IPR035776]", "CD2-associated protein, third SH3 domain [IPR035777]", "CD209-like, C-type lectin-like domain [IPR033989]", "CD47 immunoglobulin-like [IPR013270]", "CD47 transmembrane [IPR013147]", "CD80-like, immunoglobulin C2-set [IPR013162]", "CDC48, N-terminal subdomain [IPR003338]", "CDC48, domain 2 [IPR004201]", "CDH1/2, SANT-Helical linker 1 [IPR040793]", "CELF1/2, RNA recognition motif 1 [IPR034196]", "CELF1/2, RNA recognition motif 2 [IPR034198]", "CELF1/2, RNA recognition motif 3 [IPR034199]", "CENP-T/Histone H4, histone fold [IPR035425]", "CENP-V/GFA domain [IPR006913]", "CEP170, C-terminal [IPR029300]", "CFA20 domain [IPR007714]", "CHCH [IPR010625]", "CHD subfamily II, SANT-like domain [IPR009462]", "CHD, C-terminal 2 [IPR012957]", "CHD, N-terminal [IPR012958]", "CHIP, N-terminal tetratricopeptide repeat domain [IPR041312]", "CHIP/LubX , U box domain [IPR045202]", "CHORD domain [IPR007051]", "CID domain [IPR006569]", "CIDE-N domain [IPR003508]", "CLASP N-terminal domain [IPR024395]", "CLU central domain [IPR033646]", "CLU domain [IPR025697]", "CNNM, transmembrane domain [IPR002550]", "COMPASS complex Set1 subunit, N-SET domain [IPR024657]", "COP9 signalosome complex subunit 4, helix turn helix domain [IPR041406]", "COP9 signalosome complex subunit 7, helix I [IPR041481]", "COQ9 [IPR013718]", "CP2 transcription factor [IPR007604]", "CPH domain [IPR021097]", "CPL domain [IPR012959]", "CPPED1, metallophosphatase domain [IPR041867]", "CPSF2, metallo-hydrolase domain [IPR035639]", "CPSF7, RNA recognition motif [IPR034773]", "CRA domain [IPR013144]", "CRAL-TRIO lipid binding domain [IPR001251]", "CRIB domain [IPR000095]", "CRK, C-terminal SH3 domain [IPR035458]", "CRK, N-terminal SH3 domain [IPR035457]", "CS domain [IPR007052]", "CSK-like, SH2 domain [IPR035027]", "CSN8/PSMD8/EIF3K [IPR033464]", "CTLH, C-terminal LisH motif [IPR006595]", "CTLH/CRA C-terminal to LisH motif domain [IPR024964]", "CTP synthase GATase domain [IPR033828]", "CTP synthase, N-terminal [IPR017456]", "CUB domain [IPR000859]", "CUT domain [IPR003350]", "CXC domain [IPR026489]", "CYRIA/CYRIB, Rac1 binding domain [IPR009828]", "Cadherin prodomain [IPR014868]", "Cadherin, N-terminal [IPR013164]", "Cadherin, cytoplasmic domain [IPR000233]", "Cadherin-like [IPR002126]", "Calcineurin-like phosphoesterase domain, ApaH type [IPR004843]", "Calcineurin-like phosphoesterase domain, lpxH-type [IPR024654]", "Calcium binding and coiled-coil domain-like [IPR012852]", "Calcium uniporter protein, C-terminal [IPR006769]", "Calcium/calmodulin-dependent protein kinase II, association-domain [IPR013543]", "Calcyclin-binding Protein, CS domain [IPR037893]", "Calpain subdomain III [IPR033883]", "Calponin homology domain [IPR001715]", "Calsyntenin, C-terminal [IPR045588]", "Caprin-1 dimerization domain [IPR041637]", "Carbamoyl-phosphate synthase large subunit, CPSase domain [IPR005483]", "Carbamoyl-phosphate synthase small subunit, GATase1 domain [IPR035686]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain [IPR002474]", "Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain [IPR005479]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain [IPR005480]", "Carbohydrate kinase PfkB [IPR011611]", "Carboxylase, conserved domain [IPR003379]", "Carboxypeptidase D, carboxypeptidase-like domain 2 [IPR034224]", "Carboxypeptidase D, carboxypeptidase-like domain 3 [IPR033848]", "Carnitine O-palmitoyltransferase, N-terminal [IPR032476]", "Casein kinase substrate, phosphoprotein PP28 [IPR019380]", "Caspase recruitment domain [IPR031964]", "Cathepsin C [IPR039412]", "Cathepsin C exclusion [IPR014882]", "Cation-transporting P-type ATPase, C-terminal [IPR006068]", "Cation-transporting P-type ATPase, N-terminal [IPR004014]", "Cationic amino acid transporter, C-terminal [IPR029485]", "Cdc23 [IPR007192]", "Cdc37, C-terminal [IPR013873]", "Cdc37, Hsp90 binding [IPR013874]", "Cdc37, N-terminal domain [IPR013855]", "Cdc6, C-terminal [IPR015163]", "Cell division control protein 73, C-terminal [IPR031336]", "Cellular tumor antigen p53, transactivation domain 2 [IPR040926]", "Centromere protein CENP-B, C-terminal domain [IPR015115]", "Centrosomin, N-terminal motif 1 [IPR012943]", "Chaperone DnaJ, C-terminal [IPR002939]", "Chitinase II [IPR011583]", "Choline/carnitine acyltransferase domain [IPR039551]", "Choloylglycine hydrolase/NAAA C-terminal [IPR029132]", "Chromatin assembly factor 1 subunit B, C-terminal domain [IPR029129]", "Chromatin assembly factor 1 subunit p150, C-terminal [IPR029105]", "Chromatin assembly factor 1 subunit p150, N-terminal [IPR029091]", "Chromatin target of PRMT1 protein, C-terminal [IPR025715]", "Chromo domain [IPR023780]", "Chromo domain subgroup [IPR017984]", "Chromo shadow domain [IPR008251]", "Chromo/chromo shadow domain [IPR000953]", "Chromosome passenger complex (CPC) protein INCENP N-terminal [IPR022006]", "Chromosome segregation protein Spc25, C-terminal [IPR013255]", "Circularly permuted (CP)-type guanine nucleotide-binding (G) domain [IPR030378]", "Citron homology (CNH) domain [IPR001180]", "Class I myosin tail homology domain [IPR010926]", "Class I myosin, motor domain [IPR036072]", "Class II PurE [IPR033626]", "Class II aldolase/adducin N-terminal [IPR001303]", "Class VI myosin, motor domain [IPR036114]", "Class XVIII myosin, motor domain [IPR036064]", "Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain [IPR003164]", "Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain [IPR008152]", "Clathrin, heavy chain, linker, core motif [IPR015348]", "Clathrin/coatomer adaptor, adaptin-like, N-terminal [IPR002553]", "Cleavage and polyadenylation specificity factor 2, C-terminal [IPR025069]", "Cleavage stimulation factor subunit 1, dimerisation domain [IPR032028]", "Cleavage stimulation factor subunit 2, hinge domain [IPR025742]", "Cleavage/polyadenylation specificity factor, A subunit, C-terminal [IPR004871]", "Cleavage/polyadenylation specificity factor, A subunit, N-terminal [IPR018846]", "Clp ATPase, C-terminal [IPR019489]", "Clustered mitochondria protein, N-terminal [IPR028275]", "Clusterin, C-terminal [IPR016015]", "Clusterin, N-terminal [IPR016014]", "Cns1/TTC4, wheel domain [IPR044059]", "CoA-binding [IPR003781]", "Coactivator CBP, pKID [IPR003102]", "Coagulation factor 5/8 C-terminal domain [IPR000421]", "Coatomer beta subunit, C-terminal [IPR011710]", "Coatomer beta subunit, appendage platform domain [IPR029446]", "Coatomer subunit gamma, C-terminal [IPR032154]", "Coatomer, WD associated region [IPR006692]", "Coatomer, alpha subunit, C-terminal [IPR010714]", "Coatomer, gamma subunit, appendage, Ig-like subdomain [IPR013040]", "Cobalamin (vitamin B12)-binding domain [IPR006158]", "Cobalamin (vitamin B12)-binding module, cap domain [IPR003759]", "Cobalamin adenosyltransferase-like [IPR016030]", "Coilin, N-terminal domain [IPR031722]", "Cold shock domain [IPR011129]", "Cold-shock (CSD) domain [IPR019844]", "Cold-shock protein, DNA-binding [IPR002059]", "Complement Clr-like EGF domain [IPR026823]", "Complex 1 LYR protein domain [IPR008011]", "Condensin complex subunit 1, C-terminal [IPR032682]", "Condensin complex subunit 1, N-terminal [IPR024324]", "Cop9 signalosome subunit 5 C-terminal domain [IPR040961]", "Copine, C-terminal [IPR010734]", "Copine, C2B domain [IPR037768]", "Core histone macro-H2A, macro domain [IPR035796]", "Cortactin, SH3 domain [IPR035716]", "Creatinase, N-terminal [IPR000587]", "Cro/C1-type helix-turn-helix domain [IPR001387]", "Cullin homology domain [IPR016158]", "Cullin protein, neddylation domain [IPR019559]", "Cullin, N-terminal [IPR001373]", "Cwf19-like protein, C-terminal domain-2 [IPR006767]", "Cwf19-like, C-terminal domain-1 [IPR006768]", "Cyclic nucleotide-binding domain [IPR000595]", "Cyclin, C-terminal domain [IPR004367]", "Cyclin, N-terminal [IPR006671]", "Cyclin-A, N-terminal APC/C binding region [IPR032447]", "Cyclin-dependent kinase 11/PITSLRE, catalytic domain [IPR045267]", "Cyclin-like [IPR013763]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain [IPR002130]", "Cystatin domain [IPR000010]", "Cysteine-rich flanking region, C-terminal [IPR000483]", "Cystine knot, C-terminal [IPR006207]", "Cytidine and deoxycytidylate deaminase domain [IPR002125]", "Cytochrome C oxidase subunit II, transmembrane domain [IPR011759]", "Cytochrome b-c1 complex subunit Rieske, transmembrane domain [IPR004192]", "Cytochrome b5-like heme/steroid binding domain [IPR001199]", "Cytochrome c oxidase assembly factor 3, mitochondrial, coiled-coil domain [IPR018628]", "Cytochrome c oxidase subunit 2, C-terminal [IPR034210]", "Cytochrome c oxidase subunit II-like C-terminal [IPR002429]", "Cytochrome c oxidase, subunit II [IPR014222]", "Cytoplasmic activation/proliferation-associated protein-1 C term [IPR022070]", "Cytoskeleton-associated protein 2, C-terminal [IPR029197]", "Cytosolic fatty-acid binding [IPR000463]", "D domain of beta-TrCP [IPR021977]", "D-3-phosphoglycerate dehydrogenase, ASB domain [IPR045626]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain [IPR006140]", "D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain [IPR006139]", "DALR anticodon binding [IPR008909]", "DAMP1, SANT/Myb-like domain [IPR032563]", "DAZ-associated protein 1, RNA recognition motif 1 [IPR034134]", "DAZ-associated protein 1, RNA recognition motif 2 [IPR034131]", "DBC1/CARP1 catalytically inactive NUDIX hydrolase domain [IPR025954]", "DBINO domain [IPR020838]", "DBP10, C-terminal [IPR012541]", "DDE superfamily endonuclease domain [IPR004875]", "DDHD domain [IPR004177]", "DDT domain [IPR018501]", "DDX18/Has1, DEAD-box helicase domain [IPR044773]", "DDX41, DEAD-box helicase domain [IPR044113]", "DDX47/Rrp3, DEAD-box helicase domain [IPR044765]", "DDX52/Rok1, DEAD-box helicase domain [IPR044764]", "DEAD box protein 17, ATP-binding domain [IPR046330]", "DEAD/DEAH box helicase domain [IPR011545]", "DEAD2 [IPR010614]", "DEK, C-terminal [IPR014876]", "DEP domain [IPR000591]", "DET1- and DDB1-associated protein 1, N-terminal [IPR018276]", "DEUBAD domain [IPR044867]", "DExH-box ATP-dependent RNA helicase, R3H domain [IPR034083]", "DFDF domain [IPR025762]", "DHHA1 domain [IPR003156]", "DHX15, DEXH-box helicase domain [IPR044756]", "DHX57, UBA domain [IPR042615]", "DHX8/ Prp22, DEXH-box helicase domain [IPR044762]", "DHX9, DEXH-box helicase domain [IPR044447]", "DHX9, first double-stranded RNA binding domain [IPR044445]", "DHX9, second double-stranded RNA binding domain [IPR044446]", "DIX domain [IPR001158]", "DJ-1/PfpI [IPR002818]", "DM10 domain [IPR006602]", "DMAP1-binding domain [IPR010506]", "DML1/Misato, tubulin domain [IPR029209]", "DNA (cytosine-5)-methyltransferase 1, replication foci domain [IPR022702]", "DNA binding HTH domain, Psq-type [IPR007889]", "DNA damage inducible protein 1 ubiquitin-like domain [IPR033882]", "DNA fragmentation factor 45kDa, middle domain [IPR015121]", "DNA helicase, DnaB-like, C-terminal [IPR007694]", "DNA ligase 3, BRCT domain [IPR031916]", "DNA ligase, ATP-dependent, C-terminal [IPR012309]", "DNA ligase, ATP-dependent, N-terminal [IPR012308]", "DNA ligase, ATP-dependent, central [IPR012310]", "DNA methyltransferase 1-associated 1 [IPR008468]", "DNA mismatch repair protein MutS, C-terminal [IPR000432]", "DNA mismatch repair protein MutS, clamp [IPR007861]", "DNA mismatch repair protein MutS, connector domain [IPR007860]", "DNA mismatch repair protein MutS, core [IPR007696]", "DNA mismatch repair protein MutS-like, N-terminal [IPR007695]", "DNA mismatch repair protein family, N-terminal [IPR002099]", "DNA mismatch repair protein, S5 domain 2-like [IPR013507]", "DNA polymerase alpha catalytic subunit, N-terminal domain [IPR024647]", "DNA polymerase alpha catalytic subunit, catalytic domain [IPR045846]", "DNA polymerase alpha, subunit B, N-terminal [IPR013627]", "DNA polymerase alpha/delta/epsilon, subunit B [IPR007185]", "DNA polymerase delta subunit 2, C-terminal domain [IPR041863]", "DNA polymerase delta subunit, OB-fold domain [IPR040663]", "DNA polymerase epsilon, catalytic subunit A, C-terminal [IPR013697]", "DNA recombination and repair protein RecA, monomer-monomer interface [IPR020587]", "DNA repair Nbs1, C-terminal [IPR013908]", "DNA replication complex GINS protein SLD5, C-terminal [IPR031633]", "DNA replication factor RFC1, C-terminal [IPR013725]", "DNA topoisomerase 2, TOPRIM domain [IPR034157]", "DNA topoisomerase 3-like, TOPRIM domain [IPR034144]", "DNA topoisomerase I, DNA binding, eukaryotic-type [IPR008336]", "DNA topoisomerase I, catalytic core, eukaryotic-type [IPR013500]", "DNA topoisomerase I, eukaryotic-type [IPR013499]", "DNA topoisomerase, type IA, DNA-binding domain [IPR003602]", "DNA topoisomerase, type IA, central [IPR013497]", "DNA topoisomerase, type IA, domain 2 [IPR003601]", "DNA topoisomerase, type IA, zn finger [IPR013498]", "DNA topoisomerase, type IIA, domain A [IPR002205]", "DNA topoisomerase, type IIA, subunit B, domain 2 [IPR013506]", "DNA-binding RFX-type winged-helix domain [IPR003150]", "DNA-binding protein SMUBP-2, R3H domain [IPR034072]", "DNA-dependent protein kinase catalytic subunit, CC3 [IPR012582]", "DNA-dependent protein kinase catalytic subunit, CC5 [IPR045581]", "DNA-dependent protein kinase catalytic subunit, catalytic domain [IPR037706]", "DNA-directed DNA polymerase, family B, exonuclease domain [IPR006133]", "DNA-directed DNA polymerase, family B, multifunctional domain [IPR006134]", "DNA-directed RNA polymerase I subunit RPA2, domain 4 [IPR009674]", "DNA-directed RNA polymerase III subunit RPC1, C-terminal [IPR035698]", "DNA-directed RNA polymerase III subunit RPC1, N-terminal [IPR035697]", "DNA-directed RNA polymerase, N-terminal [IPR029262]", "DNA-directed RNA polymerase, RpoA/D/Rpb3-type [IPR011263]", "DNA-directed RNA polymerase, insert domain [IPR011262]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain [IPR007120]", "DNA-repair protein Xrcc1, N-terminal [IPR002706]", "DNA/RNA non-specific endonuclease [IPR001604]", "DNA/RNA-binding protein Alba-like [IPR002775]", "DNA/RNA-binding protein Kin17, WH-like domain [IPR019447]", "DNA2/NAM7 helicase, helicase domain [IPR041677]", "DNA2/NAM7 helicase-like, C-terminal [IPR041679]", "DOCKER domain [IPR027357]", "DPF1-3, N-terminal domain [IPR025750]", "DSBA-like thioredoxin domain [IPR001853]", "DTHCT [IPR012542]", "DUS-like, FMN-binding domain [IPR035587]", "DWNN domain [IPR014891]", "DZF domain [IPR006561]", "Damage-control phosphatase ARMT1-like, metal-binding domain [IPR002791]", "Daxx, N-terminal Rassf1C-interacting domain [IPR031333]", "Dbl homology (DH) domain [IPR000219]", "Death domain [IPR000488]", "Dedicator of cytokinesis C, C2 domain [IPR037808]", "Dedicator of cytokinesis C/D, N-terminal [IPR021816]", "Dehydrogenase, E1 component [IPR001017]", "Deoxynucleoside kinase domain [IPR031314]", "Desmoplakin, SH3 domain [IPR041615]", "Desmoplakin, spectrin-like domain [IPR041573]", "Deubiquitinating enzyme MINDY-3/4, conserved domain [IPR025257]", "Diacylglycerol kinase, catalytic domain [IPR001206]", "Diacylglycerol/phorbol-ester binding [IPR020454]", "Diaphanous autoregulatory (DAD) domain [IPR014767]", "Dicer dimerisation domain [IPR005034]", "Dicer, double-stranded RNA-binding domain [IPR044441]", "Dihydrofolate reductase domain [IPR001796]", "Dilute domain [IPR002710]", "Dis3-like cold-shock domain 2 [IPR041505]", "Dishevelled C-terminal [IPR024580]", "Dishevelled protein domain [IPR003351]", "Disintegrin domain [IPR001762]", "Disks large homologue 1, N-terminal PEST domain [IPR019590]", "Disulphide isomerase [IPR005788]", "DnaJ domain [IPR001623]", "DnaJ homologue subfamily C, GRV2/DNAJC13, N-terminal domain [IPR045802]", "DnaJ-like protein C11, C-terminal [IPR024586]", "Dolichyl-phosphate beta-glucosyltransferase [IPR035518]", "Dolichyldiphosphatase, PAP2 domain [IPR039667]", "Domain of unknown function DUF1087 [IPR009463]", "Domain of unknown function DUF1115 [IPR010541]", "Domain of unknown function DUF1605 [IPR011709]", "Domain of unknown function DUF1747 [IPR013719]", "Domain of unknown function DUF1899 [IPR015048]", "Domain of unknown function DUF3350 [IPR021785]", "Domain of unknown function DUF3385, target of rapamycin protein [IPR024585]", "Domain of unknown function DUF3456 [IPR021852]", "Domain of unknown function DUF3480 [IPR022557]", "Domain of unknown function DUF3517 [IPR021905]", "Domain of unknown function DUF3677 [IPR022145]", "Domain of unknown function DUF382 [IPR007180]", "Domain of unknown function DUF4042 [IPR025283]", "Domain of unknown function DUF4149 [IPR025423]", "Domain of unknown function DUF4171 [IPR025228]", "Domain of unknown function DUF4195 [IPR025243]", "Domain of unknown function DUF4208 [IPR025260]", "Domain of unknown function DUF4217 [IPR025313]", "Domain of unknown function DUF4749 [IPR031847]", "Domain of unknown function DUF5050 [IPR032485]", "Domain of unknown function DUF5577 [IPR041477]", "Domain of unknown function DUF5600 [IPR040990]", "Domain of unknown function DUF5604 [IPR040880]", "Domain of unknown function DUF5921 [IPR045803]", "Domain of unknown function DUF625 [IPR006887]", "Double-stranded RNA-binding domain [IPR014720]", "Down-regulated-in-metastasis protein [IPR011430]", "Drebrin-like protein, SH3 domain [IPR035717]", "Drought induced 19 protein type, zinc-binding domain [IPR008598]", "Dual specificity phosphatase, catalytic domain [IPR000340]", "Dual specificity protein phosphatase domain [IPR020422]", "Dynamin GTPase effector [IPR003130]", "Dynamin stalk domain [IPR000375]", "Dynamin, GTPase domain [IPR001401]", "Dynamin, N-terminal [IPR045063]", "Dynamin-like GTPase OPA1, C-terminal [IPR045817]", "Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]", "Dynein associated protein [IPR022157]", "Dynein heavy chain AAA lid domain [IPR041658]", "Dynein heavy chain region D6 P-loop domain [IPR004273]", "Dynein heavy chain, AAA 5 extension domain [IPR041466]", "Dynein heavy chain, AAA module D4 [IPR024317]", "Dynein heavy chain, ATP-binding dynein motor region [IPR035706]", "Dynein heavy chain, C-terminal domain [IPR041228]", "Dynein heavy chain, coiled coil stalk [IPR024743]", "Dynein heavy chain, hydrolytic ATP-binding dynein motor region [IPR035699]", "Dynein heavy chain, linker [IPR013602]", "Dynein heavy chain, tail [IPR013594]", "Dyskerin-like [IPR012960]", "E1A-binding protein p400, N-terminal [IPR031575]", "E3 ligase, CCCH-type zinc finger [IPR041367]", "E3 ubiquitin ligase EDD, ubiquitin-associated domain [IPR024725]", "E3 ubiquitin ligase UBR4, C-terminal [IPR025704]", "E3 ubiquitin ligase, domain of unknown function DUF908 [IPR010309]", "E3 ubiquitin ligase, domain of unknown function DUF913 [IPR010314]", "E3 ubiquitin-protein ligase CBL-B, RING finger, HC subclass [IPR039520]", "E3 ubiquitin-protein ligase RNF114, RING finger, HC subclass [IPR042716]", "E3 ubiquitin-protein ligase UBR4, N-terminal [IPR045841]", "EB-1 binding [IPR009232]", "EB1, C-terminal [IPR004953]", "ECSIT, C-terminal domain [IPR029342]", "EF hand associated, type-1 [IPR013566]", "EF hand associated, type-2 [IPR013567]", "EF-hand domain [IPR002048]", "EF-hand domain, type 1 [IPR015153]", "EF-hand domain, type 2 [IPR015154]", "EF-hand, Ca insensitive [IPR014837]", "EFG, domain V [IPR035649]", "EGF-like calcium-binding domain [IPR001881]", "EGF-like domain [IPR000742]", "EGF-like domain, extracellular [IPR013111]", "EH domain [IPR000261]", "EH domain-containing protein, N-terminal [IPR031692]", "EIF2AK2, first double-stranded RNA binding domain [IPR044452]", "EIF2AK2, second double-stranded RNA binding domain [IPR044453]", "ELK domain [IPR005539]", "ELM2 domain [IPR000949]", "ELMO domain [IPR006816]", "ELMO, armadillo-like helical domain [IPR024574]", "ELYS, beta-propeller domain [IPR032040]", "ELYS-like domain [IPR025151]", "ENTH domain [IPR013809]", "ER membrane protein complex subunit 1, C-terminal [IPR011678]", "ER membrane protein complex subunit 7, beta-sandwich domain [IPR019008]", "ERAP1-like C-terminal domain [IPR024571]", "ERCC3/RAD25/XPB helicase, C-terminal domain [IPR032438]", "ERM family, FERM domain C-lobe [IPR041789]", "ERV/ALR sulfhydryl oxidase domain [IPR017905]", "ERdj5, C-terminal thioredoxin domain [IPR035674]", "ERdj5, first thioredoxin domain [IPR035673]", "ERp29, N-terminal [IPR012883]", "EVE domain [IPR002740]", "EWS, RNA recognition motif [IPR034869]", "EXOG, C-terminal [IPR041003]", "EXPERA domain [IPR033118]", "EYA domain [IPR006545]", "EYA domain, metazoan [IPR042577]", "EZH2, SET domain [IPR044439]", "Electron transfer flavoprotein, alpha subunit, C-terminal [IPR014731]", "Electron transfer flavoprotein, alpha subunit, N-terminal [IPR033947]", "Electron transfer flavoprotein, alpha/beta-subunit, N-terminal [IPR014730]", "Electron transfer flavoprotein, beta subunit, N-terminal [IPR033948]", "Elongation Factor G, domain II [IPR041095]", "Elongation factor 1 beta central acidic region, eukaryote [IPR018940]", "Elongation factor 1B gamma, C-terminal [IPR001662]", "Elongation factor 4, domain IV [IPR035654]", "Elongation factor EFG, domain V-like [IPR000640]", "Elongation factor G, domain III [IPR009022]", "Elongation factor Tu (EF-Tu), GTP-binding domain [IPR041709]", "Elongation factor Tu, domain 2 [IPR033720]", "Elp3/MiaB/NifB [IPR006638]", "Emerin, LEM domain [IPR034989]", "Endonuclease/exonuclease/phosphatase [IPR005135]", "Endophilin-A, SH3 domain [IPR035824]", "Endophilin-B1, BAR domain [IPR035695]", "Endoplasmic reticulum resident protein 29, C-terminal [IPR011679]", "Endoplasmic reticulum resident protein 44, TRX-like domain b [IPR041870]", "Endoplasmic reticulum resident protein 44, TRX-like domain b' [IPR041862]", "Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]", "Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]", "Enhancer of mRNA-decapping protein 4, WD40 repeat region [IPR032401]", "Enolase, C-terminal TIM barrel domain [IPR020810]", "Enolase, N-terminal [IPR020811]", "Enoyl-CoA hydratase/isomerase domain [IPR045004]", "Ephrin receptor ligand binding domain [IPR001090]", "Ephrin receptor, transmembrane domain [IPR027936]", "Ephrin type-A receptor 7, ligand binding domain [IPR034283]", "Era-type guanine nucleotide-binding (G) domain [IPR030388]", "Eukaryotic Ribosomal Protein L27, KOW domain [IPR041991]", "Eukaryotic glycogen debranching enzyme, N-terminal domain [IPR029436]", "Eukaryotic translation initiation factor 2D, SUI1 domain [IPR039759]", "Eukaryotic translation initiation factor 3 subunit E, N-terminal [IPR019010]", "Eukaryotic translation initiation factor 3 subunit G, N-terminal [IPR024675]", "Exocyst complex component EXOC2/Sec5, N-terminal domain [IPR039481]", "Exonuclease 1-like, PIN-like domain [IPR044752]", "Exonuclease, RNase T/DNA polymerase III [IPR013520]", "Exonuclease-1, H3TH domain [IPR037315]", "Exoribonuclease Xrn1, D2/D3 domain [IPR041106]", "Exoribonuclease, phosphorolytic domain 1 [IPR001247]", "Exoribonuclease, phosphorolytic domain 2 [IPR015847]", "Exosome complex component CSL4, C-terminal [IPR019495]", "Exosome complex component, N-terminal domain [IPR025721]", "Exosome complex exonuclease RRP44, S1 domain [IPR033770]", "Exosome-associated factor Rrp6, N-terminal [IPR012588]", "Exportin-1, C-terminal [IPR014877]", "Exportin-1/Importin-beta-like [IPR013598]", "Exportin-2, C-terminal [IPR005043]", "Exportin-2, central domain [IPR013713]", "Exportin-5, C-terminal domain [IPR045478]", "Exportin-T, C-terminal domain [IPR045546]", "Extended PHD (ePHD) domain [IPR034732]", "Extended synaptotagmin, C-terminal C2 domain [IPR037752]", "Extended synaptotagmin, C2A domain [IPR037733]", "Extended synaptotagmin, C2B domain [IPR037749]", "Extracellular Endonuclease, subunit A [IPR020821]", "F-BAR domain [IPR031160]", "F-box domain [IPR001810]", "FACT complex subunit POB3-like, N-terminal PH domain [IPR035417]", "FACT complex subunit Spt16 domain [IPR013953]", "FACT complex subunit Spt16, N-terminal lobe domain [IPR029148]", "FACT complex subunit Spt16, peptidase M24-like domain [IPR033825]", "FAD dependent oxidoreductase [IPR006076]", "FAD dependent oxidoreductase, central domain [IPR032503]", "FAD linked oxidase, N-terminal [IPR006094]", "FAD-binding domain, PCMH-type [IPR016166]", "FAD-binding domain, ferredoxin reductase-type [IPR017927]", "FAD-dependent oxidoreductase 2, FAD binding domain [IPR003953]", "FAD-linked oxidase, C-terminal [IPR004113]", "FAD/NAD(P)-binding domain [IPR023753]", "FAF1, UBA-like domain [IPR044541]", "FAM3C (ILEI) domain [IPR039475]", "FAM69, protein-kinase domain [IPR022049]", "FANCI helical domain 1 [IPR029310]", "FANCI helical domain 2 [IPR029312]", "FANCI solenoid 1 cap [IPR029305]", "FANCI solenoid 1 domain [IPR029308]", "FANCI solenoid 2 domain [IPR029315]", "FANCI solenoid 3 domain [IPR029313]", "FANCI solenoid 4 domain [IPR029314]", "FARP1/FARP2/FRMD7, FERM domain C-lobe [IPR041788]", "FAS-associated factor 1-like, UBX domain [IPR033043]", "FAST kinase leucine-rich [IPR010622]", "FAST kinase-like protein, subdomain 2 [IPR013579]", "FATC domain [IPR003152]", "FCH domain [IPR001060]", "FCP1 homology domain [IPR004274]", "FDF domain [IPR019050]", "FERM adjacent (FA) [IPR014847]", "FERM central domain [IPR019748]", "FERM domain [IPR000299]", "FERM, C-terminal PH-like domain [IPR018980]", "FERM, N-terminal [IPR018979]", "FF domain [IPR002713]", "FFD box [IPR025761]", "FGFR1 oncogene partner (FOP), N-terminal dimerisation domain [IPR018993]", "FHOD1, N-terminal GTPase-binding domain [IPR041387]", "FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]", "FKBP12-rapamycin binding domain [IPR009076]", "FKBP3, basic tilted helix bundle domain [IPR041200]", "FNBP1L, F-BAR domain [IPR035494]", "FNBP1L, SH3 domain [IPR035493]", "FOX1, RNA recognition motif [IPR034237]", "FY-rich, C-terminal [IPR003889]", "FY-rich, N-terminal [IPR003888]", "FYVE zinc finger [IPR000306]", "Far upstream element-binding protein, C-terminal [IPR015096]", "Far11/STRP, C-terminal [IPR021819]", "Far11/STRP, N-terminal [IPR012486]", "Fascin domain [IPR022768]", "Fatty acid desaturase domain [IPR005804]", "Fatty acid hydroxylase [IPR006694]", "Fatty acyl-CoA reductase, C-terminal [IPR033640]", "Fatty acyl-coenzyme A reductase, NAD-binding domain [IPR013120]", "Fcf2 pre-rRNA processing, C-terminal [IPR014810]", "Ferrochelatase, C-terminal [IPR033644]", "Ferrochelatase, N-terminal [IPR033659]", "Fibronectin type II domain [IPR000562]", "Fibronectin type III [IPR003961]", "First polo-box domain [IPR033701]", "Flavodoxin-like [IPR001094]", "Flavodoxin/nitric oxide synthase [IPR008254]", "Flavoprotein pyridine nucleotide cytochrome reductase [IPR001709]", "Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain [IPR008333]", "Follistatin-like, N-terminal [IPR003645]", "Follistatin/Osteonectin EGF domain [IPR015369]", "Fork head domain [IPR001766]", "Forkhead-associated (FHA) domain [IPR000253]", "Formin, FH2 domain [IPR015425]", "Formin, FH3 domain [IPR010472]", "Formin, GTPase-binding domain [IPR010473]", "Formyl transferase, N-terminal [IPR002376]", "Fox-1 C-terminal domain [IPR025670]", "Fragile X-related 1 protein, C-terminal core [IPR022034]", "Fragile X-related 1 protein, C-terminal region 1 [IPR032172]", "Fragile X-related 1 protein, C-terminal region 3 [IPR032177]", "Fragile X-related mental retardation protein, C-terminal region 2 [IPR032196]", "Fumarase C, C-terminal [IPR018951]", "Fumarate lyase, N-terminal [IPR022761]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal [IPR015939]", "Fumarylacetoacetase, N-terminal [IPR015377]", "Fumarylacetoacetase-like, C-terminal [IPR011234]", "Fungal lipase-like domain [IPR002921]", "Furin-like cysteine-rich domain [IPR006211]", "Fxr1, tudor domain [IPR041560]", "Fzo/mitofusin HR2 domain [IPR006884]", "G-patch domain [IPR000467]", "G-patch domain and KOW motifs-containing protein, KOW 1 [IPR041993]", "G-patch domain and KOW motifs-containing protein, KOW 2 [IPR041994]", "G-protein gamma-like domain [IPR015898]", "G-protein, beta subunit [IPR001632]", "G3BP1, RNA recognition motif [IPR034374]", "G3BP2, RNA recognition motif [IPR034376]", "GAD domain [IPR029351]", "GAR domain [IPR003108]", "GAT domain [IPR004152]", "GB1/RHD3-type guanine nucleotide-binding (G) domain [IPR030386]", "GCC2, Rab binding domain [IPR032023]", "GCF, C-terminal [IPR022783]", "GHMP kinase N-terminal domain [IPR006204]", "GHMP kinase, C-terminal domain [IPR013750]", "GINS complex protein Sld5, alpha-helical domain [IPR038749]", "GINS subunit, domain A [IPR021151]", "GMP phosphodiesterase, delta subunit [IPR008015]", "GMP synthase, C-terminal [IPR001674]", "GMP synthase, glutamine amidotransferase [IPR004739]", "GMP synthetase ATP pyrophosphatase domain [IPR025777]", "GNAT domain [IPR000182]", "GOLD domain [IPR009038]", "GPAT/DHAPAT, acyltransferase domain [IPR041728]", "GPR domain [IPR000965]", "GRAM domain [IPR004182]", "GRASP-type PDZ domain [IPR024958]", "GRB2, C-terminal SH3 domain [IPR035643]", "GRB2, N-terminal SH3 domain [IPR035641]", "GRIP domain [IPR000237]", "GRSF-1, RNA recognition motif 1 [IPR034425]", "GRSF-1, RNA recognition motif 2 [IPR034424]", "GRSF-1, RNA recognition motif 3 [IPR034426]", "GTP binding domain [IPR006073]", "GTP binding protein 1-like, GTP-binding domain [IPR035531]", "GTP binding protein, second domain [IPR031662]", "GTP-binding protein LepA, C-terminal [IPR013842]", "GTP-binding protein TrmE, N-terminal [IPR018948]", "GTP1/OBG domain [IPR006169]", "GTPase effector domain [IPR020850]", "GUCT [IPR012562]", "GYF domain 2 [IPR025640]", "GYF domain [IPR003169]", "Galactokinase, N-terminal domain [IPR019539]", "Galactose mutarotase, N-terminal barrel [IPR031727]", "Galectin, carbohydrate recognition domain [IPR001079]", "Gamma tubulin complex component protein, N-terminal [IPR041470]", "Gamma tubulin complex component, C-terminal [IPR040457]", "Gamma-adaptin ear (GAE) domain [IPR008153]", "Gamma-butyrobetaine hydroxylase-like, N-terminal [IPR010376]", "Gamma-glutamyl cyclotransferase-like [IPR013024]", "Gcp-like domain [IPR000905]", "Gelsolin-like domain [IPR007123]", "Gfo/Idh/MocA-like oxidoreductase, N-terminal [IPR000683]", "GlmS/AgaS, SIS domain 1 [IPR035466]", "GlmS/FrlB, SIS domain 2 [IPR035490]", "Glucosamine/galactosamine-6-phosphate isomerase [IPR006148]", "Glucose-6-phosphate dehydrogenase, C-terminal [IPR022675]", "Glucose-6-phosphate dehydrogenase, NAD-binding [IPR022674]", "Glucosidase 2 subunit beta-like [IPR036607]", "Glucosidase II beta subunit, N-terminal [IPR028146]", "Glucosyltransferase 24, catalytic domain [IPR040497]", "Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal [IPR006096]", "Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain [IPR006097]", "Glutaminase, EF-hand domain [IPR041541]", "Glutamine amidotransferase [IPR017926]", "Glutamine amidotransferase type 2 domain [IPR017932]", "Glutamine-Leucine-Glutamine, QLQ [IPR014978]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain 2 [IPR007638]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal [IPR007639]", "Glutamyl-tRNA synthetase [IPR033910]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain [IPR020059]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain [IPR020058]", "Glutaredoxin [IPR002109]", "Glutaredoxin, PICOT-like [IPR033658]", "Glutathione S-transferase, C-terminal [IPR004046]", "Glutathione S-transferase, C-terminal-like [IPR010987]", "Glutathione S-transferase, N-terminal [IPR004045]", "Glutathione S-transferases, class Zeta , C-terminal [IPR034330]", "Glutathione S-transferases, class Zeta , N-terminal [IPR034333]", "Glutathione synthase, substrate-binding domain [IPR004887]", "Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain [IPR020828]", "Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain [IPR020829]", "Glycerol-3-phosphate acyltransferase-like, C-terminal domain [IPR045520]", "Glycine cleavage T-protein, C-terminal barrel domain [IPR013977]", "Glycogen debranching enzyme, C-terminal [IPR032790]", "Glycogen debranching enzyme, central domain [IPR032788]", "Glycogen debranching enzyme, glucanotransferase domain [IPR032792]", "Glycogen synthase kinase 3, catalytic domain [IPR039192]", "Glycoside hydrolase 35, catalytic domain [IPR031330]", "Glycoside hydrolase family 18, catalytic domain [IPR001223]", "Glycoside hydrolase family 2, catalytic domain [IPR006103]", "Glycoside hydrolase family 20, catalytic domain [IPR015883]", "Glycoside hydrolase family 31, N-terminal domain [IPR025887]", "Glycoside hydrolase family 38, N-terminal domain [IPR000602]", "Glycoside hydrolase family 38, central domain [IPR015341]", "Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich [IPR006102]", "Glycosyl hydrolase family 30, TIM-barrel domain [IPR033453]", "Glycosyl hydrolase family 30, beta sandwich domain [IPR033452]", "Glycosyl hydrolase family 38, C-terminal [IPR011682]", "Glycosyl hydrolase family 63, C-terminal [IPR031335]", "Glycosyl hydrolase family 63, N-terminal [IPR031631]", "Glycosyl hydrolase, family 13, catalytic domain [IPR006047]", "Glycosyl hydrolases family 2, sugar binding domain [IPR006104]", "Glycosyl hydrolases family 38, C-terminal beta sandwich domain [IPR041147]", "Glycosyl transferase CAP10 domain [IPR006598]", "Glycosyl transferase, family 1 [IPR001296]", "Glycosyltransferase 2-like [IPR001173]", "Glycosyltransferase subfamily 4-like, N-terminal domain [IPR028098]", "Glycyl-tRNA synthetase-like core domain [IPR033731]", "Glyoxalase domain-containing protein 4, C-terminal [IPR043194]", "Glyoxalase/fosfomycin resistance/dioxygenase domain [IPR004360]", "Golgi pH regulator, conserved domain [IPR022535]", "Golgin subfamily A, conserved domain [IPR043976]", "Growth factor receptor domain 4 [IPR032778]", "Growth hormone-inducible transmembrane protein [IPR035871]", "Guanine nucleotide exchange factor, N-terminal [IPR032691]", "Guanine nucleotide-binding protein-like 3, N-terminal domain [IPR014813]", "Guanylate kinase-like domain [IPR008144]", "Guanylate kinase/L-type calcium channel beta subunit [IPR008145]", "Guanylate-binding protein, N-terminal [IPR015894]", "Guanylate-binding protein/Atlastin, C-terminal [IPR003191]", "HAD-superfamily hydrolase, subfamily IIID [IPR011943]", "HAD-superfamily hydrolase,subfamily IIIA [IPR006549]", "HAUS augmin-like complex subunit 6, N-terminal [IPR028163]", "HBS1-like protein, N-terminal [IPR015033]", "HD domain [IPR006674]", "HD/PDEase domain [IPR003607]", "HDGF-related, PWWP domain [IPR035496]", "HECT domain [IPR000569]", "HELLS, N-terminal [IPR044753]", "HELP [IPR005108]", "HERC2, APC10 domain [IPR037976]", "HERC2, zinc finger, ZZ-type [IPR041987]", "HHH domain 9 [IPR041692]", "HIRAN domain [IPR014905]", "HIT-like domain [IPR011146]", "HOOK, N-terminal [IPR043936]", "HORMA domain [IPR003511]", "HR1 rho-binding domain [IPR011072]", "HRDC domain [IPR002121]", "HSPA4, nucleotide-binding domain [IPR042052]", "HSPA4L, nucleotide-binding domain [IPR042708]", "HSPH1, nucleotide-binding domain [IPR042053]", "HTH CenpB-type DNA-binding domain [IPR006600]", "HTTM [IPR011020]", "HUWE1, UBA domain [IPR041918]", "Heat shock 70kDa protein 14, nucleotide-binding domain [IPR042049]", "Heat shock chaperonin-binding [IPR006636]", "Heat shock protein DnaJ, cysteine-rich domain [IPR001305]", "Heat shock protein Hsp90, N-terminal [IPR020575]", "Heat shock protein beta-1, ACD domain [IPR037876]", "Helical and beta-bridge domain [IPR010643]", "Helicase XPB/Ssl2, N-terminal domain [IPR032830]", "Helicase domain [IPR007807]", "Helicase superfamily 1/2, ATP-binding domain [IPR014001]", "Helicase superfamily 1/2, ATP-binding domain, DinG/Rad3-type [IPR014013]", "Helicase, C-terminal [IPR001650]", "Helicase-associated domain [IPR007502]", "Helicase-like, DEXD box c2 type [IPR006554]", "Helicase/SANT-associated domain [IPR014012]", "Helicase/UvrB, N-terminal [IPR006935]", "Helix-hairpin-helix DNA-binding motif, class 1 [IPR003583]", "Helix-turn-helix DNA-binding domain of Spt6 [IPR028088]", "Hemimethylated DNA-binding domain [IPR011722]", "Hepatitis delta antigen (HDAg) domain [IPR037517]", "Hepatocyte growth factor-regulated tyrosine kinase substrate, helical domain [IPR024641]", "Hermansky-Pudlak syndrome 3 protein, C-terminal domain [IPR029438]", "Hermansky-Pudlak syndrome 3 protein, N-terminal domain [IPR029437]", "Hermansky-Pudlak syndrome 3, central region [IPR028167]", "Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 1 [IPR034544]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 2 [IPR034548]", "Heterogeneous nuclear ribonucleoprotein R, RNA recognition motif 2 [IPR034411]", "Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778]", "Hexokinase, C-terminal [IPR022673]", "Hexokinase, N-terminal [IPR022672]", "HhH-GPD domain [IPR003265]", "High mobility group box domain 5 [IPR029215]", "High mobility group box domain [IPR009071]", "Histidine kinase domain [IPR005467]", "Histidine kinase/HSP90-like ATPase [IPR003594]", "Histone H2A, C-terminal domain [IPR032454]", "Histone H2A/H2B/H3 [IPR007125]", "Histone acetyl transferase HAT1 N-terminal [IPR019467]", "Histone acetyltransferase domain, MYST-type [IPR002717]", "Histone chaperone domain CHZ [IPR019098]", "Histone deacetylase complex subunit SAP130, C-terminal domain [IPR031963]", "Histone deacetylase domain [IPR023801]", "Histone deacetylase interacting domain [IPR013194]", "Histone methyltransferase, Tudor domain 1 [IPR041291]", "Histone methyltransferase, Tudor domain 2 [IPR041292]", "Histone-arginine methyltransferase CARM1, N-terminal [IPR020989]", "Histone-binding protein RBBP4, N-terminal [IPR022052]", "HnRNP M, nuclear localisation signal [IPR024666]", "Homeobox domain [IPR001356]", "Homeobox protein Hox1A3 N-terminal [IPR022067]", "Homocysteine-binding domain [IPR003726]", "Hook, C-terminal [IPR008636]", "Hotdog acyl-CoA thioesterase (ACOT)-type domain [IPR033120]", "Hpc2-related domain [IPR014840]", "HuR, RNA recognition motif 2 [IPR034996]", "Hyaluronan-mediated motility receptor, C-terminal [IPR031794]", "Hyaluronan/mRNA-binding protein [IPR006861]", "Hydroxymethylglutaryl-coenzyme A synthase, C-terminal domain [IPR013746]", "Hydroxymethylglutaryl-coenzyme A synthase, N-terminal [IPR013528]", "I-kappa-kinase-beta NEMO binding domain [IPR022007]", "I/LWEQ domain [IPR002558]", "IBR domain [IPR002867]", "IF2a, S1-like domain [IPR044126]", "IGF2BP1, RNA recognition motif 1 [IPR034837]", "IGF2BP1, RNA recognition motif 2 [IPR034842]", "IGF2BP2, RNA recognition motif 1 [IPR034843]", "IGF2BP3, RNA recognition motif 2 [IPR034844]", "IKBKB, scaffold dimerization domain [IPR041185]", "ILEI/PANDER domain [IPR039477]", "IMD/I-BAR domain [IPR013606]", "IMP dehydrogenase/GMP reductase [IPR001093]", "IPS1, CARD domain [IPR042144]", "IPT domain [IPR002909]", "IRS-type PTB domain [IPR002404]", "IRSp53, SH3 domain [IPR035594]", "ISWI, HAND domain [IPR015194]", "Ima1, N-terminal domain [IPR018617]", "Immunoglobulin C1-set [IPR003597]", "Immunoglobulin I-set [IPR013098]", "Immunoglobulin V-set domain [IPR013106]", "Immunoglobulin [IPR013151]", "Immunoglobulin subtype 2 [IPR003598]", "Immunoglobulin subtype [IPR003599]", "Immunoglobulin-like domain [IPR007110]", "Importin-alpha, importin-beta-binding domain [IPR002652]", "Importin-beta, N-terminal domain [IPR001494]", "Initiation factor eIF-4 gamma, MA3 [IPR003891]", "Inner centromere protein, ARK-binding domain [IPR005635]", "Inositol polyphosphate 5-phosphatase, clathrin binding domain [IPR031995]", "Inositol polyphosphate-related phosphatase [IPR000300]", "Int12, PHD finger [IPR039054]", "Integrator complex subunit 11, MBL-fold [IPR041897]", "Integrator complex subunit 14, C-terminal [IPR045814]", "Integrator complex subunit 3, N-terminal [IPR019333]", "Integrin beta N-terminal [IPR033760]", "Integrin beta subunit, VWA domain [IPR002369]", "Integrin beta subunit, cytoplasmic domain [IPR014836]", "Integrin beta subunit, tail [IPR012896]", "Integrin beta, epidermal growth factor-like domain 1 [IPR040622]", "Integrin-linked protein kinase, pseudokinase domain [IPR035692]", "Interferon regulatory factor 2-binding protein 1 & 2, zinc finger [IPR022750]", "Intermediate filament head, DNA-binding domain [IPR006821]", "Intermediate filament, rod domain [IPR039008]", "Intracellular hyaluronan-binding protein 4, N-terminal domain [IPR032381]", "Intron-binding protein aquarius, N-terminal [IPR032174]", "Ion transporter-like, CBS domain [IPR044751]", "Iron sulphur domain-containing, mitoNEET, N-terminal [IPR019610]", "Iron-binding zinc finger, CDGSH type [IPR018967]", "Isochorismatase-like [IPR000868]", "Isoleucyl tRNA synthetase type 1, anticodon-binding domain [IPR033708]", "Isoleucyl tRNA synthetase type 2, anticodon-binding domain [IPR033709]", "Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain [IPR044861]", "Isopropylmalate dehydrogenase-like domain [IPR024084]", "JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]", "JNK-interacting protein, leucine zipper II [IPR032486]", "JNK/Rab-associated protein-1, N-terminal [IPR019143]", "JmjC domain [IPR003347]", "JmjN domain [IPR003349]", "Jumonji, helical domain [IPR041070]", "K Homology domain [IPR004087]", "K Homology domain, type 1 [IPR004088]", "K Homology domain, type 2 [IPR004044]", "KASH domain [IPR012315]", "KHDRBS, Qua1 domain [IPR032571]", "KMT2A, PHD domain 1 [IPR042023]", "KMT2A, PHD domain 2 [IPR042025]", "KMT2A, PHD domain 3 [IPR044133]", "KMT2A, ePHD domain [IPR041958]", "KN17, SH3-like C-terminal domain [IPR041330]", "KOW [IPR005824]", "Kazal domain [IPR002350]", "Kin17, KOW domain [IPR041995]", "Kinase associated domain 1 (KA1) [IPR001772]", "Kindlin-2, N-terminal [IPR040790]", "Kindlin/fermitin, PH domain [IPR037837]", "Kinesin motor domain [IPR001752]", "Kinesin-associated [IPR032405]", "Kinesin-associated microtubule-binding domain [IPR025901]", "Kinesin-like KIF1-type [IPR022140]", "Kinesin-like [IPR022164]", "Kinesin-like protein Kif23, Arf6-interacting domain [IPR032384]", "Kinetochore protein Nuf2, N-terminal [IPR005549]", "Kri1-like, C-terminal [IPR024626]", "Krr1, KH1 domain [IPR041174]", "Ku, C-terminal [IPR014893]", "Ku70/Ku80 C-terminal arm [IPR005160]", "Ku70/Ku80 beta-barrel domain [IPR006164]", "Ku70/Ku80, N-terminal alpha/beta [IPR005161]", "L27 domain [IPR004172]", "L27 domain, C-terminal [IPR014775]", "L27-1 [IPR015143]", "L27-2 [IPR015132]", "L27-N [IPR015145]", "LAIKA domain [IPR045353]", "LARP4, RNA recognition motif [IPR034903]", "LARP5, RNA recognition motif [IPR034900]", "LARP7, RNA recognition motif 1 [IPR034887]", "LARP7, RNA recognition motif 2 [IPR034910]", "LEM domain [IPR003887]", "LEM-like domain [IPR013146]", "LETM1, ribosome-binding domain [IPR033122]", "LETM1-like [IPR011685]", "LIS1 homology motif [IPR006594]", "LRRC8, pannexin-like TM region [IPR021040]", "LSM domain, eukaryotic/archaea-type [IPR001163]", "LSM-interacting domain [IPR008669]", "LYRM2, LYR domain [IPR045293]", "La protein, xRRM domain [IPR014886]", "La-related protein 7, La domain [IPR034946]", "La-type HTH domain [IPR006630]", "Lactate/malate dehydrogenase, C-terminal [IPR022383]", "Lactate/malate dehydrogenase, N-terminal [IPR001236]", "Lamin tail domain [IPR001322]", "Lamin-B receptor of TUDOR domain [IPR019023]", "Lamina-associated polypeptide 2 alpha, C-terminal [IPR021623]", "Laminin G domain [IPR001791]", "Laminin IV [IPR000034]", "Laminin IV type B [IPR013015]", "Laminin, N-terminal [IPR008211]", "Laminin-type EGF domain [IPR002049]", "Large proline-rich protein BAG6 [IPR021925]", "Lasp1, SH3 domain [IPR035630]", "Legume-like lectin [IPR005052]", "Lens epithelium-derived growth factor, integrase-binding domain [IPR021567]", "Lethal giant larvae homologue 2 [IPR013577]", "Leucine zipper, homeobox-associated [IPR003106]", "Leucine-rich repeat N-terminal domain [IPR000372]", "Leukocyte surface antigen CD47, IgV [IPR037805]", "Linker histone H1/H5, domain H15 [IPR005818]", "Lipocalin/cytosolic fatty-acid binding domain [IPR000566]", "Listerin, zinc finger, RING-type [IPR039804]", "Lon, substrate-binding domain [IPR003111]", "Longin domain [IPR010908]", "Lsm14-like, N-terminal [IPR025609]", "Lsm16, N-terminal [IPR034107]", "LsmAD domain [IPR009604]", "Lysine-specific demethylase-like domain [IPR013637]", "Lysine-tRNA ligase, class II, N-terminal [IPR044136]", "Lysophosphatidylcholine acyltransferase LPCAT1-like [IPR045252]", "Lysyl-tRNA synthetase, class II, C-terminal [IPR018149]", "M60-like domain, N-terminal [IPR035423]", "MABP domain [IPR023341]", "MAGE homology domain [IPR002190]", "MAM domain [IPR000998]", "MAN1, RNA recognition motif [IPR034394]", "MANSC domain [IPR013980]", "MATH/TRAF domain [IPR002083]", "MCM N-terminal domain [IPR027925]", "MCM OB domain [IPR033762]", "MCM domain [IPR001208]", "MCM, AAA-lid domain [IPR041562]", "MD-2-related lipid-recognition domain [IPR003172]", "MDM2-binding protein, N-terminal domain [IPR029421]", "MDM2-binding protein, central domain [IPR029420]", "MDN2-binding protein, C-terminal domain [IPR029418]", "MEF-2, RNA recognition motif 1 [IPR034630]", "MEF-2, RNA recognition motif 3 [IPR034631]", "MENTAL domain [IPR019498]", "MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]", "MHC class I, alpha chain, C-terminal [IPR010579]", "MHC class I-like antigen recognition-like [IPR011161]", "MIA2, SH3 domain [IPR035555]", "MIF4G-like, type 1 [IPR015172]", "MIF4G-like, type 2 [IPR015174]", "MIF4G-like, type 3 [IPR003890]", "MIRO domain [IPR020860]", "MIT domain [IPR007330]", "MKI67 FHA domain-interacting nucleolar phosphoprotein, FHA Ki67 binding [IPR021043]", "MMS19, C-terminal [IPR024687]", "MMS19, N-terminal [IPR029240]", "MMS22-like, C-terminal [IPR029424]", "MOSC, N-terminal beta barrel [IPR005303]", "MPN domain [IPR037518]", "MPP1, SH3 domain [IPR035475]", "MPP2, SH3 domain [IPR035602]", "MPP5, SH3 domain [IPR035601]", "MPP6, SH3 domain [IPR035603]", "MPP7, SH3 domain [IPR035599]", "MRG domain [IPR026541]", "MRH domain [IPR044865]", "MRPL44, double-stranded RNA binding domain [IPR044444]", "MTMR6, PH-GRAM domain [IPR035998]", "MYND-like zinc finger [IPR031615]", "MYST, zinc finger domain [IPR040706]", "Mab-21 domain [IPR024810]", "Macro domain [IPR002589]", "Macroglobulin domain MG3 [IPR041555]", "Macroglobulin domain [IPR002890]", "Mad3/Bub1 homology region 1 [IPR013212]", "Major facilitator superfamily domain [IPR020846]", "Major sperm protein (MSP) domain [IPR000535]", "Malectin domain [IPR021720]", "Malic enzyme, N-terminal domain [IPR012301]", "Malic enzyme, NAD-binding [IPR012302]", "Man1/Src1, C-terminal [IPR018996]", "Manganese/iron superoxide dismutase, C-terminal [IPR019832]", "Manganese/iron superoxide dismutase, N-terminal [IPR019831]", "Mannose-1-phosphate guanyltransferase, N-terminal domain [IPR045233]", "MaoC-like dehydratase domain [IPR002539]", "Marvel domain [IPR008253]", "Matrin-3, RNA recognition motif 1 [IPR034928]", "Matrin-3, RNA recognition motif 2 [IPR034930]", "Matrin/U1-C, C2H2-type zinc finger [IPR000690]", "Matrin/U1-C-like, C2H2-type zinc finger [IPR003604]", "Mcm6, C-terminal winged-helix domain [IPR041024]", "Mediator complex, subunit Med1 [IPR019680]", "Mediator complex, subunit Med12 [IPR019035]", "Mediator complex, subunit Med12, LCEWAV-domain [IPR021990]", "Mediator complex, subunit Med12, catenin-binding [IPR021989]", "Mediator complex, subunit Med25, NR box [IPR021406]", "Mediator complex, subunit Med25, PTOV domain [IPR021394]", "Mediator complex, subunit Med25, synapsin 1 [IPR021397]", "Mediator of RNA polymerase II transcription subunit 25, von Willebrand factor type A domain [IPR021419]", "Membrane insertase YidC/Oxa1, C-terminal [IPR028055]", "Metallo-beta-lactamase [IPR001279]", "Metastasis-associated protein MTA1, R1 domain [IPR035170]", "Metaxin, glutathione S-transferase domain [IPR033468]", "Methionine synthase, B12-binding domain [IPR033706]", "Methionine--tRNA ligase, N-terminal [IPR041598]", "Methioninyl-tRNA synthetase core domain [IPR033911]", "Methionyl-tRNA synthetase, anticodon-binding domain [IPR041872]", "Methionyl/Leucyl tRNA synthetase [IPR015413]", "Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding [IPR013155]", "Methyl-CpG DNA binding [IPR001739]", "Methyl-CpG binding protein 2/3, C-terminal domain [IPR025884]", "Methyl-CpG-binding domain protein 2/3, p55-binding region [IPR032343]", "Methylglyoxal synthase-like domain [IPR011607]", "Methylmalonyl-CoA mutase, C-terminal [IPR006159]", "Methylmalonyl-CoA mutase, alpha chain, catalytic [IPR006098]", "Methylmalonyl-CoA mutase, alpha/beta chain, catalytic [IPR006099]", "Methylthiotransferase, N-terminal [IPR013848]", "Methyltransferase domain 25 [IPR041698]", "Methyltransferase domain [IPR025714]", "Methyltransferase type 11 [IPR013216]", "Methyltransferase type 12 [IPR013217]", "Mff-like domain [IPR039433]", "Mib-herc2 [IPR010606]", "Micro-fibrillar-associated protein 1, C-terminal [IPR009730]", "Midasin AAA lid domain 5 [IPR041190]", "Midasin, AAA lid domain 7 [IPR040848]", "Minichromosome loss protein Mcl1, middle region [IPR022100]", "Misato Segment II tubulin-like domain [IPR019605]", "Mitochondrial apoptosis-inducing factor, C-terminal domain [IPR029324]", "Mitochondrial cytochrome c oxidase subunit VIc/VIIs [IPR034884]", "Mitochondrial degradasome RNA helicase subunit, C-terminal domain [IPR022192]", "Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564]", "Mitochondrial ribosomal protein L46 NUDIX [IPR033650]", "MnmE, helical domain [IPR025867]", "MoaB/Mog domain [IPR001453]", "Modifier of rudimentary, Modr [IPR009851]", "MoeA, C-terminal, domain IV [IPR005111]", "MoeA, N-terminal and linker domain [IPR005110]", "Molybdenum cofactor sulfurase, C-terminal [IPR005302]", "Molybdopterin oxidoreductase [IPR006656]", "Molybdopterin oxidoreductase, 4Fe-4S domain [IPR006963]", "Mon2, C-terminal [IPR032817]", "Mon2, dimerisation and cyclophilin-binding domain [IPR032629]", "Morc, S5 domain 2-like [IPR041006]", "Mre11 nuclease, N-terminal metallophosphatase domain [IPR041796]", "Mre11, DNA-binding [IPR007281]", "Mst1 SARAH domain [IPR024205]", "Mu homology domain [IPR028565]", "Mu2, C-terminal domain [IPR043512]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal [IPR031717]", "Multiple myeloma tumor-associated protein 2-like, N-terminal [IPR019315]", "Multiprotein bridging factor 1, N-terminal [IPR013729]", "Myb domain [IPR017930]", "Myo-inositol-1-phosphate synthase, GAPDH-like [IPR013021]", "Myosin VI, cargo binding domain [IPR032412]", "Myosin head, motor domain [IPR001609]", "Myosin phosphatase-RhoA interacting protein, PH domain [IPR039597]", "Myosin tail [IPR002928]", "Myosin, N-terminal, SH3-like [IPR004009]", "Myosin-binding domain [IPR026859]", "Myotubularin-like phosphatase domain [IPR010569]", "Myristoyl-CoA:protein N-myristoyltransferase, C-terminal [IPR022677]", "Myristoyl-CoA:protein N-myristoyltransferase, N-terminal [IPR022676]", "N-acetylgalactosaminyltransferase [IPR045885]", "N-acetylneuraminic acid synthase, N-terminal [IPR013132]", "N-terminal extension of GAT domain [IPR041198]", "NACHT nucleoside triphosphatase [IPR007111]", "NAD(P) binding domain of glutamate dehydrogenase [IPR033922]", "NAD(P) transhydrogenase, alpha subunit, C-terminal [IPR024605]", "NAD(P)-binding domain [IPR016040]", "NAD-dependent epimerase/dehydratase [IPR001509]", "NAD/GMP synthase [IPR022310]", "NADH pyrophosphatase-like, N-terminal [IPR015375]", "NADH-quinone oxidoreductase, chain G, C-terminal [IPR015405]", "NADH-quinone oxidoreductase, subunit D [IPR001135]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain [IPR011538]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain [IPR019575]", "NADH:ubiquinone oxidoreductase, 30kDa subunit [IPR001268]", "NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding [IPR019574]", "NADH:ubiquinone oxidoreductase-like, 20kDa subunit [IPR006137]", "NADP transhydrogenase beta-like domain [IPR034300]", "NADP-dependent oxidoreductase domain [IPR023210]", "NDPK7, first NDPk domain [IPR035525]", "NDPK7, second NDPk domain [IPR037993]", "NDUFA6, LYR domain [IPR045299]", "NDUFB9, LYR domain [IPR045292]", "NECAP, PHear domain [IPR012466]", "NEDD8 ultimate buster 1, ubiquitin-like domain [IPR041207]", "NET domain [IPR027353]", "NF-kappaB-repression factor, R3H domain [IPR034071]", "NFACT protein, C-terminal [IPR021846]", "NFACT, RNA-binding domain [IPR008532]", "NFRKB winged helix-like domain [IPR025220]", "NFkappaB IPT domain [IPR033926]", "NGN domain [IPR005100]", "NGN domain, eukaryotic [IPR039385]", "NHL2, NHL repeat domain [IPR045302]", "NIF system FeS cluster assembly, NifU, C-terminal [IPR001075]", "NIF system FeS cluster assembly, NifU, N-terminal [IPR002871]", "NIPSNAP [IPR012577]", "NLE [IPR012972]", "NOG, C-terminal [IPR012973]", "NOG1, N-terminal helical domain [IPR041623]", "NOP5, N-terminal [IPR012974]", "NOPS [IPR012975]", "NOSIC [IPR012976]", "NOT2/NOT3/NOT5, C-terminal [IPR007282]", "NP60, PWWP domain [IPR035501]", "NPL4, zinc-binding putative [IPR007716]", "NSD, Cys-His rich domain [IPR041306]", "NUC153 [IPR012580]", "NUC205 domain [IPR012584]", "NUDIX hydrolase [IPR020476]", "NUDIX hydrolase domain [IPR000086]", "NVL2, nucleolin binding domain [IPR031996]", "Nascent polypeptide-associated complex NAC domain [IPR002715]", "Nck1, SH2 domain [IPR035882]", "Nck1, SH3 domain 1 [IPR035562]", "Nck1, SH3 domain 2 [IPR035564]", "Nck1, SH3 domain 3 [IPR035565]", "Nck2, SH2 domain [IPR035883]", "Nck2, SH3 domain 1 [IPR035559]", "Nck2, SH3 domain 2 [IPR035560]", "Nck2, SH3 domain 3 [IPR035561]", "Negative elongation factor E, RNA recognition motif [IPR034637]", "Neurabin-1/2, PDZ domain [IPR040645]", "Neurexin/syndecan/glycophorin C [IPR003585]", "Neurobeachin-like, DUF1088 [IPR010508]", "Neurobeachin/BDCP, DUF4704 [IPR031570]", "Neuroblastoma-amplified sequence, N-terminal [IPR029145]", "Neuropilin, C-terminal [IPR022579]", "Nibrin, second BRCT domain [IPR032429]", "Nicastrin, small lobe [IPR041084]", "Nicotinamide phosphoribosyltransferase, N-terminal domain [IPR041529]", "Nicotinate/nicotinamide phosphoribosyltransferase [IPR041525]", "Niemann-Pick C1, N-terminal [IPR032190]", "Nin one binding (NOB1) Zn-ribbon-like [IPR014881]", "Nischarin, PX domain [IPR037904]", "Nitric oxide synthase-interacting protein, zinc-finger [IPR031790]", "Nmd3, N-terminal [IPR007064]", "Non-canonical purine NTP phosphatase/PRRC1 [IPR026533]", "Nop domain [IPR002687]", "Nop2p [IPR011023]", "Novel protein kinase C delta, catalytic domain [IPR034667]", "Npc2 like, ML domain [IPR033916]", "Nrap protein domain 1 [IPR035082]", "Nrap protein, domain 2 [IPR035367]", "Nrap protein, domain 3 [IPR035368]", "Nrap protein, domain 4 [IPR035369]", "Nrap protein, domain 5 [IPR035370]", "Nrap protein, domain 6 [IPR035371]", "Nuclear RNA export factor Tap, RNA-binding domain [IPR015245]", "Nuclear condensin complex subunit 3, C-terminal domain [IPR025977]", "Nuclear hormone receptor, ligand-binding domain [IPR000536]", "Nuclear migration protein nudC [IPR032572]", "Nuclear pore complex protein Nup214, phenylalanine-glycine (FG) domain [IPR041553]", "Nuclear pore complex, NUP2/50/61 [IPR015007]", "Nuclear pore localisation protein NPL4, C-terminal [IPR007717]", "Nuclear pore localisation protein Npl4, ubiquitin-like domain [IPR024682]", "Nuclear protein 96 [IPR021967]", "Nuclear transport factor 2 domain [IPR002075]", "Nuclear transport factor 2, eukaryote [IPR018222]", "Nuclear-interacting partner of ALK/Rsm1-like [IPR013909]", "Nucleolar 27S pre-rRNA processing, Urb2/Npa2, C-terminal [IPR018849]", "Nucleolar GTP-binding protein 1, Rossman-fold domain [IPR010674]", "Nucleolar GTP-binding protein 2, N-terminal domain [IPR012971]", "Nucleolar complex-associated protein 3, N-terminal [IPR011501]", "Nucleolar pre-ribosomal-associated protein 1, C-terminal domain [IPR032436]", "Nucleolar pre-ribosomal-associated protein 1, N-terminal [IPR021714]", "Nucleolar protein 7, C-terminal [IPR012579]", "Nucleolar protein 8, RNA recognition motif [IPR034138]", "Nucleolin, RNA recognition motif 1 [IPR034230]", "Nucleolin, RNA recognition motif 2 [IPR034233]", "Nucleolin, RNA recognition motif 3 [IPR034234]", "Nucleolin, RNA recognition motif 4 [IPR034235]", "Nucleophosmin, C-terminal [IPR032569]", "Nucleoplasmin core domain [IPR024057]", "Nucleoporin Nup153, N-terminal [IPR013913]", "Nucleoporin Nup188, N-terminal [IPR018864]", "Nucleoporin Nup54, alpha-helical domain [IPR025712]", "Nucleoporin, NSP1-like, C-terminal [IPR007758]", "Nucleoporin, Nup133/Nup155-like, C-terminal [IPR007187]", "Nucleoporin, Nup133/Nup155-like, N-terminal [IPR014908]", "Nucleoprotein TPR/MLP1 [IPR012929]", "Nucleoredoxin, redox inactive TRX-like domain b' [IPR041861]", "Nucleoside diphosphate kinase-like domain [IPR034907]", "Nucleoside phosphorylase domain [IPR000845]", "Nucleotide exchange factor Fes1 [IPR013918]", "Nucleotidyl transferase domain [IPR005835]", "NudC N-terminal domain [IPR025934]", "NudC domain-containing protein 2, p23 domain [IPR037902]", "NuoE domain [IPR042128]", "Nup358/RanBP2 E3 ligase domain [IPR022011]", "Nup54, C-terminal interacting domain [IPR040985]", "NusG, N-terminal [IPR006645]", "O-GlcNAc transferase, C-terminal [IPR029489]", "OB-fold nucleic acid binding domain, AA-tRNA synthetase-type [IPR004365]", "OBG-type guanine nucleotide-binding (G) domain [IPR031167]", "OCRE domain [IPR041591]", "OCRL1, PH domain [IPR037787]", "OCRL1/INPP5B, INPP5c domain [IPR037793]", "OTU domain [IPR003323]", "Occludin homology domain [IPR010844]", "Olduvai domain [IPR010630]", "Orc1-like, AAA ATPase domain [IPR041664]", "Origin recognition complex subunit 3, N-terminal [IPR045667]", "Origin recognition complex subunit 3, insertion domain [IPR045663]", "Origin recognition complex subunit 3, winged helix C-terminal [IPR040855]", "Orotate phosphoribosyl transferase domain [IPR004467]", "Orotidine 5'-phosphate decarboxylase domain [IPR001754]", "Ovarian carcinoma immunoreactive antigen domain [IPR009764]", "Oxidoreductase FAD/NAD(P)-binding [IPR001433]", "Oxidoreductase, N-terminal domain [IPR041694]", "Oxoglutarate/iron-dependent dioxygenase [IPR005123]", "P-type ATPase, C-terminal [IPR032630]", "P-type ATPase, N-terminal [IPR032631]", "P-type ATPase, haloacid dehalogenase domain [IPR044492]", "P-type trefoil domain [IPR000519]", "PA domain [IPR003137]", "PABP, RNA recognition motif 2 [IPR045305]", "PACSIN1/PACSIN2, SH3 domain [IPR035743]", "PACSIN2, F-BAR domain [IPR037453]", "PADR1 domain [IPR012982]", "PAP/25A-associated [IPR002058]", "PARN, R3H domain [IPR034042]", "PAZ domain [IPR003100]", "PB1 domain [IPR000270]", "PD-(D/E)XK endonuclease-like domain, AddAB-type [IPR038726]", "PDIP3, RNA recognition motif [IPR034784]", "PDZ domain 6 [IPR041489]", "PDZ domain [IPR001478]", "PDZ-associated domain of NMDA receptors [IPR019583]", "PET domain [IPR010442]", "PET testin [IPR033724]", "PH-BEACH domain [IPR023362]", "PHR [IPR012983]", "PI31 proteasome regulator, N-terminal [IPR021625]", "PI31 proteasome regulator, C-terminal [IPR013886]", "PI3K-C2-alpha, catalytic domain [IPR037705]", "PI4-kinase, N-terminal [IPR045495]", "PIH1, N-terminal [IPR012981]", "PIH1D1/2/3, CS-like domain [IPR041442]", "PIK-related kinase [IPR014009]", "PIK-related kinase, FAT [IPR003151]", "PIN domain [IPR002716]", "PITH domain [IPR010400]", "PKD domain [IPR000601]", "PKD/Chitinase domain [IPR022409]", "PLAA family ubiquitin binding domain [IPR015155]", "PLC-gamma, C-terminal SH2 domain [IPR035023]", "PLC-gamma, N-terminal SH2 domain [IPR035024]", "PLD-like domain [IPR032803]", "PNK, FHA domain [IPR041388]", "POLO box domain [IPR000959]", "POPLD domain [IPR012590]", "POTRA domain [IPR034746]", "PP2B, metallophosphatase domain [IPR041751]", "PP5, C-terminal metallophosphatase domain [IPR041753]", "PPIL4-like, cyclophilin domain [IPR035538]", "PPM-type phosphatase domain [IPR001932]", "PPP domain [IPR013235]", "PRELI/MSF1 domain [IPR006797]", "PRKAA1, UBA-like autoinhibitory domain [IPR028797]", "PRKCBP1, PHD finger [IPR044075]", "PRKRA, first double-stranded RNA binding domain [IPR044465]", "PRKRA, second double-stranded RNA binding domain [IPR044466]", "PRKRA, third double-stranded RNA binding domain [IPR044467]", "PRMT5 arginine-N-methyltransferase [IPR035075]", "PRMT5, TIM barrel domain [IPR035247]", "PRMT5, oligomerisation domain [IPR035248]", "PRO8NT domain [IPR012591]", "PROCN domain [IPR012592]", "PROCT domain [IPR012984]", "PRP1 splicing factor, N-terminal [IPR010491]", "PRP8 domain IV core [IPR021983]", "PSF, NOPS domain [IPR034526]", "PSF, RNA recognition motif 1 [IPR034525]", "PSI domain [IPR016201]", "PSP, proline-rich [IPR006568]", "PSP1, RNA recognition motif 1 [IPR034522]", "PSP1, RNA recognition motif 2 [IPR034523]", "PTB/PI domain [IPR006020]", "PTBP1, RNA recognition motif 1 [IPR035000]", "PTBP1, RNA recognition motif 2-like [IPR021790]", "PTBP1, RNA recognition motif 3 [IPR035001]", "PTBP2, RNA recognition motif 1 [IPR035002]", "PTBP2, RNA recognition motif 3 [IPR034799]", "PTBP2, RNA recognition motif 4 [IPR034800]", "PUA domain [IPR002478]", "PUF60, RNA recognition motif 1 [IPR034209]", "PUF60, RNA recognition motif 2 [IPR034211]", "PUF60, RNA recognition motif 3 [IPR034212]", "PUL domain [IPR013535]", "PWI domain [IPR002483]", "PWWP domain [IPR000313]", "Paf1 complex subunit Cdc73, N-terminal domain [IPR032041]", "Palladin, C-terminal immunoglobulin-like domain [IPR033017]", "Pancreatic trypsin inhibitor Kunitz domain [IPR002223]", "Patatin-like phospholipase domain [IPR002641]", "Pentacotripeptide-repeat region of PRORP [IPR033443]", "Pep3/Vps18/deep orange [IPR007810]", "Peptidase C12, C-terminal domain [IPR041507]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase [IPR001578]", "Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394]", "Peptidase C19, ubiquitin-specific peptidase, DUSP domain [IPR006615]", "Peptidase C1A, papain C-terminal [IPR000668]", "Peptidase C1A, propeptide [IPR012599]", "Peptidase C2, calpain, catalytic domain [IPR001300]", "Peptidase C2, calpain, domain III [IPR022683]", "Peptidase C2, calpain, large subunit, domain III [IPR022682]", "Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal [IPR015211]", "Peptidase M1, membrane alanine aminopeptidase [IPR014782]", "Peptidase M12B, ADAM/reprolysin [IPR001590]", "Peptidase M12B, propeptide [IPR002870]", "Peptidase M13, C-terminal domain [IPR018497]", "Peptidase M13, N-terminal domain [IPR008753]", "Peptidase M14, carboxypeptidase A [IPR000834]", "Peptidase M16, C-terminal [IPR007863]", "Peptidase M16, N-terminal [IPR011765]", "Peptidase M16, middle/third domain [IPR032632]", "Peptidase M16C associated [IPR013578]", "Peptidase M17, leucyl aminopeptidase, C-terminal [IPR000819]", "Peptidase M17, leucyl aminopeptidase, N-terminal [IPR008283]", "Peptidase M20, dimerisation domain [IPR011650]", "Peptidase M24 [IPR000994]", "Peptidase M24, C-terminal domain [IPR032416]", "Peptidase M28 [IPR007484]", "Peptidase M3A/M3B catalytic domain [IPR001567]", "Peptidase M41 [IPR000642]", "Peptidase M41, FtsH extracellular [IPR011546]", "Peptidase M48 [IPR001915]", "Peptidase S16, Lon proteolytic domain [IPR008269]", "Peptidase S24/S26A/S26B/S26C [IPR015927]", "Peptidase S26 [IPR019533]", "Peptidase S53, activation domain [IPR015366]", "Peptidase S59, nucleoporin [IPR007230]", "Peptidase S8/S53 domain [IPR000209]", "Peptidase S8A, tripeptidyl peptidase II [IPR022229]", "Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375]", "Peptidase S9A, N-terminal domain [IPR023302]", "Peptidase family M60 domain [IPR031161]", "Peptide chain release factor class I [IPR000352]", "Peptidyl-prolyl cis-trans isomerase E, RNA recognition motif [IPR034168]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type [IPR000297]", "Pericentrin/AKAP-450 centrosomal targeting domain [IPR019528]", "Pericentriolar material 1 protein, C-terminal [IPR031446]", "Peripheral subunit-binding domain [IPR004167]", "Peroxiredoxin, C-terminal [IPR019479]", "Peroxisome membrane anchor protein Pex14p, N-terminal [IPR006785]", "PheRS DNA binding domain 2 [IPR040586]", "PheRS, DNA binding domain 1 [IPR040724]", "PheRS, DNA binding domain 3 [IPR040725]", "Phenylacetic acid degradation-related domain [IPR003736]", "Phenylalanine--tRNA ligase beta subunit, B1 domain [IPR040659]", "Phenylalanyl tRNA synthetase beta chain, core domain [IPR041616]", "Phenylalanyl-tRNA synthetase [IPR002319]", "Phosducin, thioredoxin-like domain [IPR024253]", "Phosphatidic acid phosphatase type 2/haloperoxidase [IPR000326]", "Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403]", "Phosphatidylinositol 3-kinase Ras-binding (PI3K RBD) domain [IPR000341]", "Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha, PX domain [IPR042133]", "Phosphatidylinositol-4-phosphate 5-kinase, core [IPR002498]", "Phosphatidylinositol-specific phospholipase C, X domain [IPR000909]", "Phosphoadenosine phosphosulphate reductase [IPR002500]", "Phosphoenolpyruvate carboxykinase, C-terminal P-loop domain [IPR035077]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal [IPR035078]", "Phosphofructokinase domain [IPR000023]", "Phosphoglucose isomerase, SIS domain 1 [IPR035476]", "Phosphoglucose isomerase, SIS domain 2 [IPR035482]", "Phosphoinositide 3-kinase, accessory (PIK) domain [IPR001263]", "Phospholipase C, phosphatidylinositol-specific, Y domain [IPR001711]", "Phospholipase D-like domain [IPR025202]", "Phospholipase D/Transphosphatidylase [IPR001736]", "Phospholipase/carboxylesterase/thioesterase [IPR003140]", "Phospholipid/glycerol acyltransferase [IPR002123]", "Phosphopantetheine binding ACP domain [IPR009081]", "Phosphoribosylformylglycinamidine synthase, N-terminal [IPR040707]", "Phosphoribosylformylglycinamidine synthase, linker domain [IPR041609]", "Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain [IPR020561]", "Phosphoribosylglycinamide synthetase, C-domain [IPR020560]", "Phosphoribosylglycinamide synthetase, N-terminal [IPR020562]", "Phosphoribosyltransferase domain [IPR000836]", "Phosphoribulokinase/uridine kinase [IPR006083]", "Phosphorylated adapter RNA export protein, RNA-binding domain [IPR019385]", "Phosphotyrosine interaction domain, Shc-like [IPR006019]", "Phosphotyrosine protein phosphatase I [IPR023485]", "Phox homology [IPR001683]", "Pinin/SDK [IPR006787]", "Pinin/SDK/MemA protein [IPR006786]", "Pirin, C-terminal domain [IPR008778]", "Pirin, N-terminal domain [IPR003829]", "Plasma membrane calcium transporting P-type ATPase, C-terminal [IPR022141]", "Pleckstrin homology domain 8 [IPR041680]", "Pleckstrin homology domain 9 [IPR041681]", "Pleckstrin homology domain [IPR001849]", "Pleckstrin homology domain, spectrin-type [IPR001605]", "Plectin/S10, N-terminal [IPR005326]", "Plexin, TIG domain 1 [IPR041019]", "Plexin, cytoplasmic RasGAP domain [IPR013548]", "Polo-like kinase 1, catalytic domain [IPR033702]", "Poly(A) polymerase, RNA-binding domain [IPR007010]", "Poly(A) polymerase, central domain [IPR007012]", "Poly(A)-specific ribonuclease, RNA-binding [IPR014789]", "Poly(ADP-ribose) polymerase, catalytic domain [IPR012317]", "Poly(ADP-ribose) polymerase, regulatory domain [IPR004102]", "Polyadenylate-binding protein/Hyperplastic disc protein [IPR002004]", "Polyamine biosynthesis domain [IPR030374]", "Polycomb group protein, RNA binding region [IPR033763]", "Polycomb protein, VEFS-Box [IPR019135]", "Polycomb repressive complex 2 subunit EZH1/EZH2, tri-helical domain [IPR041343]", "Polyketide synthase, C-terminal extension [IPR032821]", "Polyketide synthase, beta-ketoacyl synthase domain [IPR020841]", "Polyketide synthase, dehydratase domain [IPR020807]", "Polyketide synthase, enoylreductase domain [IPR020843]", "Polyketide synthase, ketoreductase domain [IPR013968]", "Polyketide synthase, phosphopantetheine-binding domain [IPR020806]", "Polymerase, nucleotidyl transferase domain [IPR002934]", "Polynucleotide 3'-phosphatase [IPR006551]", "Polypyrimidine tract-binding protein1/2/3, RNA recognition motif 2 [IPR034798]", "Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain [IPR032319]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain [IPR015848]", "Polysaccharide biosynthesis domain [IPR021148]", "Pop1, N-terminal [IPR009723]", "Porphobilinogen deaminase, C-terminal [IPR022418]", "Porphobilinogen deaminase, N-terminal [IPR022417]", "Possible tRNA binding domain [IPR027992]", "Post-SET domain [IPR003616]", "Potassium channel tetramerisation-type BTB domain [IPR003131]", "Potentiating neddylation domain [IPR005176]", "Pre-PUA domain [IPR041366]", "Pre-SET CXC domain [IPR041355]", "Pre-SET domain [IPR007728]", "Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term [IPR021718]", "Pre-mRNA polyadenylation factor Fip1 domain [IPR007854]", "Pre-mRNA processing factor 4 (PRP4)-like [IPR014906]", "Pre-mRNA splicing factor component Cdc5p/Cef1, C-terminal [IPR021786]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding [IPR019581]", "Pre-mRNA-processing-splicing factor 8, U6-snRNA-binding [IPR019580]", "Pre-mRNA-splicing factor 19 [IPR013915]", "Pre-mRNA-splicing factor 3 [IPR013881]", "Pre-rRNA-processing protein Ipi1, N-terminal [IPR024679]", "Pre-rRNA-processing protein RIX1, N-terminal [IPR012583]", "Prenylcysteine lyase [IPR010795]", "Probable RNA-binding protein 19, RNA recognition motif 1 [IPR034418]", "Probable RNA-binding protein 19, RNA recognition motif 2 [IPR034417]", "Probable RNA-binding protein 19, RNA recognition motif 3 [IPR034419]", "Probable RNA-binding protein 19, RNA recognition motif 4 [IPR034420]", "Probable RNA-binding protein 19, RNA recognition motif 5 [IPR034423]", "Probable RNA-binding protein 19, RNA recognition motif 6 [IPR034421]", "Proliferating cell nuclear antigen, PCNA, C-terminal [IPR022649]", "Proliferating cell nuclear antigen, PCNA, N-terminal [IPR022648]", "Proline-tRNA ligase, class II, C-terminal [IPR016061]", "Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]", "Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547]", "Prolyl 4-hydroxylase, alpha subunit [IPR006620]", "Prolyl-tRNA synthetase, catalytic domain [IPR033721]", "Propionyl-coenzyme A carboxylase, BT domain [IPR041265]", "Prostaglandin E synthase 2, C-terminal [IPR034335]", "Proteasomal ATPase OB C-terminal domain [IPR032501]", "Proteasome activator Blm10, mid region [IPR032430]", "Proteasome activator PA28, C-terminal domain [IPR003186]", "Proteasome activator PA28, N-terminal domain [IPR003185]", "Proteasome activator complex subunit 4 C-terminal domain [IPR021843]", "Proteasome alpha-subunit, N-terminal domain [IPR000426]", "Proteasome beta subunit, C-terminal [IPR024689]", "Proteasome component (PCI) domain [IPR000717]", "Protein FAM210A/B-like domain [IPR009688]", "Protein HGH1 C-terminal [IPR007206]", "Protein HGH1 N-terminal [IPR007205]", "Protein Kinase B beta, catalytic domain [IPR034677]", "Protein Kinase B, pleckstrin homology domain [IPR039026]", "Protein MMS22-like, N-terminal [IPR029425]", "Protein O-mannosyl-transferase TMTC, DUF1736 [IPR013618]", "Protein OS9-like domain [IPR012913]", "Protein RED, C-terminal [IPR012492]", "Protein Smaug, SAM domain [IPR037634]", "Protein disulfide-isomerase A3, first redox inactive TRX-like domain b [IPR041868]", "Protein disulfide-isomerase A4, TRX-like domain b [IPR041866]", "Protein disulfide-isomerase A5, N-terminal TRX-like b domain [IPR041865]", "Protein kinase B alpha, catalytic domain [IPR034676]", "Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219]", "Protein kinase domain [IPR000719]", "Protein kinase, C-terminal [IPR017892]", "Protein of unknown function DUF3504 [IPR021893]", "Protein of unknown function DUF3715 [IPR022188]", "Protein phosphatase 1 binding domain [IPR029334]", "Protein polybromo-1, Bromodomain 5 [IPR037968]", "Protein quaking, putative nuclear localisation signal [IPR032367]", "Protein-only RNase P, C-terminal [IPR031595]", "Protein-tyrosine phosphatase, catalytic [IPR003595]", "Proto-oncogene c-Rel, RHD, N-terminal subdomain [IPR042845]", "Prp31 C-terminal [IPR019175]", "Pseudouridine synthase I, TruA, alpha/beta domain [IPR020097]", "Pseudouridine synthase II, N-terminal [IPR002501]", "Pseudouridine synthase, TruD, insertion domain [IPR011760]", "Pterin-binding domain [IPR000489]", "Pumilio homology domain [IPR033133]", "Pumilio, RNA binding domain [IPR033712]", "PurE domain [IPR000031]", "PurM-like, C-terminal domain [IPR010918]", "PurM-like, N-terminal domain [IPR016188]", "Putative 5-3 exonuclease [IPR004859]", "Putative RNA methylase domain [IPR000241]", "Putative RNA-binding protein 27, RNA recognition motif [IPR034451]", "Putative WW-binding domain and destruction box [IPR033461]", "Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain [IPR004099]", "Pyridoxamine 5'-phosphate oxidase, putative [IPR011576]", "Pyridoxamine kinase/Phosphomethylpyrimidine kinase [IPR013749]", "Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal [IPR019576]", "Pyrroline-5-carboxylate reductase, catalytic, N-terminal [IPR028939]", "Pyrroline-5-carboxylate reductase, dimerisation domain [IPR029036]", "Pyruvate carboxyltransferase [IPR000891]", "Pyruvate kinase, C-terminal [IPR015795]", "Pyruvate kinase, barrel [IPR015793]", "R3H domain [IPR001374]", "RABX5, catalytic core helical domain [IPR041545]", "RACK7, Bromo domain [IPR037967]", "RAD23A/RAD23B, UBA1 domain [IPR041811]", "RAD50, zinc hook [IPR013134]", "RAP domain [IPR013584]", "RBM10, OCRE domain [IPR035618]", "RBM12, RNA recognition motif 1 [IPR034591]", "RBM12, RNA recognition motif 2 [IPR034594]", "RBM12, RNA recognition motif 3 [IPR034855]", "RBM12, RNA recognition motif 4 [IPR034856]", "RBM12, RNA recognition motif 5 [IPR034854]", "RBM12B, RNA recognition motif 2 [IPR034588]", "RBM12B, RNA recognition motif 3 [IPR034858]", "RBM14, RNA recognition motif 1 [IPR034506]", "RBM14, RNA recognition motif 2 [IPR034507]", "RBM15, RNA recognition motif 1 [IPR034470]", "RBM15, RNA recognition motif 2 [IPR034472]", "RBM15, RNA recognition motif 3 [IPR034473]", "RBM15B, RNA recognition motif 1 [IPR034475]", "RBM15B, RNA recognition motif 2 [IPR034535]", "RBM15B, RNA recognition motif 3 [IPR034536]", "RBM1CTR [IPR012604]", "RBM25, RNA recognition motif [IPR034268]", "RBM26, RNA recognition motif 1 [IPR034859]", "RBM26-like, RNA recognition motif 2 [IPR039511]", "RBM3/CIRBP, RNA recognition motif [IPR034278]", "RBM34, RNA recognition motif 1 [IPR034220]", "RBM34, RNA recognition motif 2 [IPR034221]", "RBM4, RNA recognition motif 1 [IPR034897]", "RBM4, RNA recognition motif 2 [IPR034898]", "RBM42, RNA recognition motif [IPR034215]", "RBM6, OCRE domain [IPR035617]", "RBM6, RNA recognition motif 1 [IPR034123]", "RBM6, RNA recognition motif 2 [IPR034125]", "RBM8, RNA recognition motif [IPR033744]", "RBP-J/Cbf11/Cbf12, DNA binding [IPR015351]", "RBP-Jkappa, IPT domain [IPR038007]", "RDD [IPR010432]", "RED-like, N-terminal [IPR012916]", "RH1 domain [IPR034743]", "RH2 domain [IPR034744]", "RII binding domain [IPR018459]", "RING finger protein 219, RING finger [IPR035691]", "RING-type zinc-finger, LisH dimerisation motif [IPR027370]", "RL domain [IPR041252]", "RLI, domain 1 [IPR034348]", "RNA 2-O ribose methyltransferase, substrate binding [IPR013123]", "RNA 3'-terminal phosphate cyclase domain [IPR023797]", "RNA 3'-terminal phosphate cyclase, insert domain [IPR013791]", "RNA binding activity-knot of a chromodomain [IPR025995]", "RNA exonuclease 4, DEDDh 3'-5' exonuclease domain [IPR037431]", "RNA helicase UPF1, 1B domain [IPR040812]", "RNA helicase UPF1, Cys/His rich zinc-binding domain [IPR018999]", "RNA helicase, DEAD-box type, Q motif [IPR014014]", "RNA methyltransferase bin3, C-terminal [IPR010675]", "RNA polymerase II-associated protein 1, C-terminal [IPR013929]", "RNA polymerase II-associated protein 1, N-terminal [IPR013930]", "RNA polymerase III Rpc82, C -terminal [IPR008806]", "RNA polymerase III subunit RPC82-related, helix-turn-helix [IPR013197]", "RNA polymerase Rpb1, domain 1 [IPR007080]", "RNA polymerase Rpb1, domain 3 [IPR007066]", "RNA polymerase Rpb1, domain 4 [IPR007083]", "RNA polymerase Rpb1, domain 5 [IPR007081]", "RNA polymerase Rpb1, domain 6 [IPR007075]", "RNA polymerase Rpb1, domain 7 [IPR007073]", "RNA polymerase Rpb2, domain 2 [IPR007642]", "RNA polymerase Rpb2, domain 3 [IPR007645]", "RNA polymerase Rpb2, domain 4 [IPR007646]", "RNA polymerase Rpb2, domain 5 [IPR007647]", "RNA polymerase Rpb2, domain 7 [IPR007641]", "RNA polymerase Rpb4/RPC9, core [IPR006590]", "RNA polymerase Rpb7-like , N-terminal [IPR005576]", "RNA polymerase, N-terminal [IPR006592]", "RNA polymerase, Rpb5, N-terminal [IPR005571]", "RNA polymerase, alpha subunit [IPR000722]", "RNA polymerase, beta subunit, protrusion [IPR007644]", "RNA polymerase, subunit H/Rpb5 C-terminal [IPR000783]", "RNA recognition motif domain [IPR000504]", "RNA recognition motif domain, eukaryote [IPR003954]", "RNA recognition motif, spliceosomal PrP8 [IPR019582]", "RNA-binding S4 domain [IPR002942]", "RNA-binding domain, S1 [IPR022967]", "RNA-binding protein 10, RNA recognition motif 2 [IPR034992]", "RNA-binding protein 5, RNA recognition motif 1 [IPR034991]", "RNA-binding protein 5, RNA recognition motif 2 [IPR034993]", "RNA-polymerase II-associated protein 3-like, C-terminal domain [IPR025986]", "RNA-recognition motif (RRM) Nup35-type domain [IPR007846]", "RNPS1, RNA recognition motif [IPR034201]", "RNase L inhibitor RLI-like, possible metal-binding domain [IPR007209]", "ROCK, Rho binding domain [IPR015008]", "ROK, N-terminal [IPR012987]", "RPN1, N-terminal [IPR040892]", "RPN13, DEUBAD domain [IPR032368]", "RQC domain [IPR018982]", "RUN domain [IPR004012]", "RWD domain [IPR006575]", "Rab geranylgeranyltransferase, alpha subunit, insert-domain [IPR009087]", "Rab interacting lysosomal protein, dimerization domain [IPR021563]", "Rab-GTPase-TBC domain [IPR000195]", "Rab-binding domain FIP-RBD [IPR019018]", "Rab3-GAP regulatory subunit, N-terminal [IPR032839]", "Rab3GAP catalytic subunit, C-terminal [IPR045698]", "Rab3GAP catalytic subunit, conserved domain [IPR026147]", "Rab3GAP regulatory subunit, C-terminal [IPR029257]", "Rabaptin coiled-coil domain [IPR018514]", "Rabaptin, GTPase-Rab5 binding domain [IPR015390]", "Rad21/Rec8-like protein, C-terminal, eukaryotic [IPR006909]", "Rad21/Rec8-like protein, N-terminal [IPR006910]", "Rad50, ATP-binding cassette domain [IPR045171]", "Rad50/SbcC-type AAA domain [IPR038729]", "Rad60/SUMO-like domain [IPR022617]", "Radical SAM [IPR007197]", "Radical SAM, C-terminal extension [IPR032432]", "Raly, RNA recognition motif [IPR034502]", "Ran binding domain [IPR000156]", "Ran binding protein 9/10, SPRY domain [IPR035782]", "Ran-GTPase activating protein 1, C-terminal [IPR009109]", "Ran-specific GTPase-activating protein 1, Ran-binding domain [IPR045256]", "Rap/Ran-GAP domain [IPR000331]", "Rap1 Myb domain [IPR015010]", "Rapamycin-insensitive companion of mTOR, N-terminal domain [IPR028267]", "Rapamycin-insensitive companion of mTOR, domain 4 [IPR029453]", "Rapamycin-insensitive companion of mTOR, domain 5 [IPR029452]", "Rapamycin-insensitive companion of mTOR, middle domain [IPR029451]", "Raptor, N-terminal CASPase-like domain [IPR029347]", "Ras GTPase-activating domain [IPR001936]", "Ras guanine-nucleotide exchange factors catalytic domain [IPR001895]", "Ras-associating (RA) domain [IPR000159]", "Ras-like guanine nucleotide exchange factor, N-terminal [IPR000651]", "RasGAP protein, C-terminal [IPR000593]", "RecF/RecN/SMC, N-terminal [IPR003395]", "RecQ helicase-like 5 [IPR010716]", "Receptor L-domain [IPR000494]", "Redoxin [IPR013740]", "Regulator of G protein signalling-like domain [IPR015212]", "Rel homology dimerisation domain [IPR032397]", "Rel homology domain (RHD), DNA-binding domain [IPR011539]", "Replication factor A, C-terminal [IPR013955]", "Replication factor C, C-terminal [IPR013748]", "Replication factor Mcm10, C-terminal [IPR015411]", "Replication factor-A protein 1, N-terminal [IPR007199]", "Replication protein A, C-terminal [IPR014892]", "Replication protein A, OB domain [IPR031657]", "Replication termination factor 2, RING-finger [IPR027799]", "Reprolysin domain, adamalysin-type [IPR034027]", "Reticulon [IPR003388]", "Rho GTPase-activating protein domain [IPR000198]", "Rho GTPase-binding/formin homology 3 (GBD/FH3) domain [IPR014768]", "Rho-associated protein kinase 1, HR1 [IPR037310]", "Rho-associated protein kinase 2, HR1 domain [IPR037311]", "Rhodanese-like domain [IPR001763]", "Rhs repeat-associated core [IPR022385]", "Ribonuclease H1, N-terminal [IPR011320]", "Ribonuclease HII/HIII domain [IPR024567]", "Ribonuclease II/R [IPR001900]", "Ribonuclease III domain [IPR000999]", "Ribonuclease, PIN domain [IPR033411]", "Ribonucleoprotein PTB-binding 1, RNA recognition motif 1 [IPR034633]", "Ribonucleotide reductase large subunit, C-terminal [IPR000788]", "Ribonucleotide reductase large subunit, N-terminal [IPR013509]", "Ribonucleotide reductase, class I , alpha subunit [IPR013346]", "Ribose-phosphate pyrophosphokinase, N-terminal domain [IPR029099]", "Ribosomal L28e/Mak16 [IPR029004]", "Ribosomal Protein L6, KOW domain [IPR041997]", "Ribosomal Proteins L2, RNA binding domain [IPR022666]", "Ribosomal RNA adenine methylase transferase, N-terminal [IPR020598]", "Ribosomal RNA methyltransferase FtsJ domain [IPR002877]", "Ribosomal RNA methyltransferase Spb1, domain of unknown function DUF3381 [IPR024576]", "Ribosomal RNA methyltransferase, Spb1, C-terminal [IPR012920]", "Ribosomal RNA small subunit methyltransferase F, N-terminal [IPR031341]", "Ribosomal RNA-processing protein 14/surfeit locus protein 6, C-terminal domain [IPR029190]", "Ribosomal S6 kinase, N-terminal catalytic domain [IPR041906]", "Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A [IPR023573]", "Ribosomal protein L10e/L16 [IPR016180]", "Ribosomal protein L11, C-terminal [IPR020783]", "Ribosomal protein L11, N-terminal [IPR020784]", "Ribosomal protein L14, KOW motif [IPR041985]", "Ribosomal protein L14e domain [IPR002784]", "Ribosomal protein L18e/L15P [IPR021131]", "Ribosomal protein L19, eukaryotic [IPR033935]", "Ribosomal protein L19/L19e [IPR000196]", "Ribosomal protein L2, C-terminal [IPR022669]", "Ribosomal protein L23/L25, N-terminal [IPR005633]", "Ribosomal protein L26/L24, KOW domain [IPR041988]", "Ribosomal protein L30, N-terminal [IPR012988]", "Ribosomal protein L30, ferredoxin-like fold domain [IPR016082]", "Ribosomal protein L46, N-terminal [IPR021757]", "Ribosomal protein L5 eukaryotic, C-terminal [IPR025607]", "Ribosomal protein L5, C-terminal [IPR031309]", "Ribosomal protein L5, N-terminal [IPR031310]", "Ribosomal protein L6, N-terminal [IPR005568]", "Ribosomal protein L6, alpha-beta domain [IPR020040]", "Ribosomal protein L7, eukaryotic/archaeal [IPR035808]", "Ribosomal protein L7/L12, C-terminal [IPR013823]", "Ribosomal protein L7/L12, oligomerisation [IPR008932]", "Ribosomal protein L7Ae/L30e/S12e/Gadd45 [IPR004038]", "Ribosomal protein L9, N-terminal [IPR020070]", "Ribosomal protein S10 domain [IPR027486]", "Ribosomal protein S13/S15, N-terminal [IPR012606]", "Ribosomal protein S23/S25, mitochondrial [IPR023611]", "Ribosomal protein S24/S35, mitochondrial, conserved domain [IPR019349]", "Ribosomal protein S3, C-terminal [IPR001351]", "Ribosomal protein S4, KOW domain [IPR041982]", "Ribosomal protein S4/S9, N-terminal [IPR001912]", "Ribosomal protein S4e, N-terminal [IPR013843]", "Ribosomal protein S4e, central region [IPR013845]", "Ribosomal protein S5, C-terminal [IPR005324]", "Ribosomal protein S5, N-terminal [IPR013810]", "Ribosomal protein S6 kinase alpha-3, C-terminal catalytic domain [IPR041905]", "Ribosomal protein S7 domain [IPR023798]", "Ribosomal protein/NADH dehydrogenase domain [IPR007741]", "Ribosome biogenesis protein BMS1/TSR1, C-terminal [IPR007034]", "Ribosome biogenesis protein Bms1, N-terminal [IPR037875]", "Ribosome maturation protein Sdo1/SBDS, C-terminal [IPR018978]", "Ribosome maturation protein Sdo1/SBDS, N-terminal [IPR019783]", "Ribosome receptor lysine/proline rich [IPR007794]", "Ribosome recycling factor domain [IPR023584]", "Ribosome-associated complex head domain [IPR032003]", "Ricin B, lectin domain [IPR000772]", "Rieske iron-sulphur protein, C-terminal [IPR005805]", "Right handed beta helix domain [IPR039448]", "RmlD-like substrate binding domain [IPR029903]", "Roadblock/LAMTOR2 domain [IPR004942]", "Rpn11/EIF3F, C-terminal [IPR024969]", "Rpn13/ADRM1, Pru domain [IPR044868]", "Rrp40, S1 domain [IPR037319]", "Rrp44-like cold shock domain [IPR033771]", "RuvB-like, AAA-lid domain [IPR041048]", "S-adenosyl-L-homocysteine hydrolase, NAD binding domain [IPR015878]", "S-adenosylmethionine synthetase, C-terminal [IPR022630]", "S-adenosylmethionine synthetase, N-terminal [IPR022628]", "S-adenosylmethionine synthetase, central domain [IPR022629]", "S1 domain [IPR003029]", "S1-like RNA binding domain [IPR025223]", "S100/CaBP-9k-type, calcium binding, subdomain [IPR013787]", "SAB domain [IPR007477]", "SAC domain [IPR002013]", "SAC3/GANP/THP3, conserved domain [IPR005062]", "SAF domain [IPR013974]", "SAICAR synthetase/ADE2, N-terminal [IPR028923]", "SAM domain [IPR041418]", "SAM-dependent methyltransferase RsmB/NOP2-type [IPR001678]", "SANT domain [IPR017884]", "SANT/Myb domain [IPR001005]", "SAP domain [IPR003034]", "SARAH domain [IPR011524]", "SART3, RNA recognition motif 1 [IPR034217]", "SART3, RNA recognition motif 2 [IPR034218]", "SAS-6 coiled-coil domain [IPR041513]", "SATB, CUT1-like DNA-binding domain [IPR032355]", "SATB, ubiquitin-like oligomerisation domain [IPR032392]", "SCAF4, RNA recognition motif [IPR034369]", "SCP2 sterol-binding domain [IPR003033]", "SDA1 domain [IPR007949]", "SEC23-interacting protein, SAM domain [IPR037603]", "SEP domain [IPR012989]", "SEPARIN core domain [IPR030397]", "SERRATE/Ars2 , C-terminal [IPR007042]", "SERRATE/Ars2, N-terminal [IPR021933]", "SET domain [IPR001214]", "SETD7, SET domain [IPR044436]", "SF3A2 domain [IPR031781]", "SF3A3 domain [IPR031774]", "SF3B4, RNA recognition motif 1 [IPR034158]", "SF3B4, RNA recognition motif 2 [IPR034159]", "SF3B6, RNA recognition motif [IPR034150]", "SGNH hydrolase-type esterase domain [IPR013830]", "SGS domain [IPR007699]", "SGTA, homodimerisation domain [IPR032374]", "SH2 adaptor protein C, SH2 domain [IPR035676]", "SH2 domain [IPR000980]", "SH3 domain [IPR001452]", "SH3-like domain, bacterial-type [IPR003646]", "SH3PXD2, PX domain [IPR037961]", "SH3PXD2B, SH3 domain 1 [IPR035477]", "SH3PXD2B, SH3 domain 2 [IPR035478]", "SH3PXD2B, SH3 domain 3 [IPR035479]", "SH3PXD2B, SH3 domain 4 [IPR035480]", "SHARP, RNA recognition motif 1 [IPR034172]", "SHARP, RNA recognition motif 2 [IPR034173]", "SHARP, RNA recognition motif 3 [IPR034174]", "SHARP, RNA recognition motif 4 [IPR034175]", "SIS domain [IPR001347]", "SKI-interacting protein SKIP, SNW domain [IPR004015]", "SKICH domain [IPR041611]", "SKP1 component, POZ domain [IPR016073]", "SKP1 component, dimerisation [IPR016072]", "SLC12A transporter, C-terminal [IPR018491]", "SLED domain [IPR021987]", "SLIDE domain [IPR015195]", "SLIRP, RNA recognition motif [IPR034152]", "SMAP1-like, ArfGAP domain [IPR044732]", "SMARCA1, N-terminal [IPR044755]", "SMARCC, C-terminal [IPR032451]", "SMARCC, N-terminal [IPR032450]", "SMARCC, SWIRM-associated domain [IPR032448]", "SMCs flexible hinge [IPR010935]", "SNAP-25 domain [IPR000928]", "SNARE-complex protein Syntaxin-18, N-terminal [IPR019529]", "SNF2, N-terminal [IPR000330]", "SNX17, atypical FERM-like domain [IPR037836]", "SNX2, PX domain [IPR037918]", "SNX27, PX domain [IPR037833]", "SNX27, RA domain [IPR037835]", "SNX27, atypical FERM-like domain [IPR037827]", "SNX5, PX domain [IPR042135]", "SNX6, PX domain [IPR042136]", "SNX9, SH3 domain [IPR035558]", "SPF45, RNA recognition motif [IPR034653]", "SPIN90, SH3 domain [IPR035514]", "SPIN90/Ldb17, leucine-rich domain [IPR018556]", "SPRY domain [IPR003877]", "SPRY-associated [IPR006574]", "SR140, RNA recognition motif [IPR035009]", "SRA-YDG [IPR003105]", "SRCR domain [IPR001190]", "SRCR-like domain [IPR017448]", "SREK1, RNA recognition motif 2 [IPR034192]", "SRP9 domain [IPR039432]", "SRSF1, RNA recognition motif 1 [IPR034520]", "SRSF6, RNA recognition motif 1 [IPR034511]", "SRSF7, RNA recognition motif [IPR034651]", "SRSF9, RNA recognition motif 1 [IPR034503]", "SRSF9, RNA recognition motif 2 [IPR034995]", "SSRP1 domain [IPR024954]", "STAG [IPR013721]", "STAM1, SH3 domain [IPR035657]", "STAMBP/STALP-like, MPN domain [IPR044098]", "STAR protein, homodimerisation region [IPR032377]", "STARD7, START domain [IPR041949]", "START domain [IPR002913]", "STAT transcription factor, DNA-binding [IPR013801]", "STAT transcription factor, all-alpha domain [IPR013800]", "STAT transcription factor, protein interaction [IPR013799]", "STAT1, SH2 domain [IPR035859]", "STI1 domain [IPR041243]", "STRBP, first double-stranded RNA binding domain [IPR044472]", "SUI1 domain [IPR001950]", "SUMO-activating enzyme subunit 2, C-terminal domain [IPR032426]", "SUN coiled coil domain 2 [IPR040994]", "SUN domain [IPR012919]", "SUN domain-containing protein 1, N-terminal [IPR032680]", "SUZ-C domain [IPR024642]", "SWAP/Surp [IPR000061]", "SWI/SNF-like complex subunit BAF250, C-terminal [IPR033388]", "SWIB domain [IPR019835]", "SWIB/MDM2 domain [IPR003121]", "SWIRM domain [IPR007526]", "Saccharopine dehydrogenase, NADP binding domain [IPR005097]", "Saccharopine dehydrogenase-like, C-terminal [IPR032095]", "Sam68, tyrosine-rich domain [IPR032335]", "Saposin A-type domain [IPR003119]", "Saposin B type domain [IPR008139]", "Saposin B type, region 2 [IPR008138]", "Saposin-like type B, region 1 [IPR007856]", "Sas10 C-terminal domain [IPR018972]", "Scaffold protein Nfu/NifU, N-terminal [IPR014824]", "Schlafen group 3-like, DNA/RNA helicase domain [IPR018647]", "Schlafen, AlbA_2 domain [IPR007421]", "Sec16, central conserved domain [IPR024340]", "Sec23, C-terminal [IPR037550]", "Sec23/Sec24 beta-sandwich [IPR012990]", "Sec23/Sec24, helical domain [IPR006900]", "Sec23/Sec24, trunk domain [IPR006896]", "Sec24-like, trunk domain [IPR041742]", "Sec39 domain [IPR013244]", "Sec63 domain [IPR004179]", "Sec7 domain [IPR000904]", "Sec7, C-terminal [IPR015403]", "Sec8 exocyst complex component specific domain [IPR007191]", "Second polo-box domain [IPR033695]", "Sedolisin domain [IPR030400]", "Sema domain [IPR001627]", "Senescence/spartin-associated, C-terminal [IPR009686]", "Sentrin-specific protease 3/5, conserved domain [IPR045577]", "Septin-type guanine nucleotide-binding (G) domain [IPR030379]", "Sequestosome-1, PB1 domain [IPR034866]", "Sequestosome-1, UBA domain [IPR033741]", "Serine aminopeptidase, S33 [IPR022742]", "Serine hydroxymethyltransferase-like domain [IPR039429]", "Serine-tRNA ligase catalytic core domain [IPR033729]", "Serine-tRNA synthetase, type1, N-terminal [IPR015866]", "Serine-threonine protein phosphatase, N-terminal [IPR031675]", "Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245]", "Serine/arginine-rich splicing factor SRSF4-like, RNA recognition motif 1 [IPR035585]", "Serine/threonine-protein PRP4, catalytic domain [IPR044092]", "Serine/threonine-protein kinase N, C2 domain [IPR037784]", "Serine/threonine-protein kinase N, first HR1 domain [IPR037313]", "Serine/threonine-protein kinase N1, second HR1 domain [IPR037317]", "Serine/threonine-protein kinase Nek9, catalytic domain [IPR042767]", "Serine/threonine-protein kinase OSR1/WNK, CCT domain [IPR024678]", "Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase [IPR006186]", "Serpin H1, serpin domain [IPR033830]", "Serpin domain [IPR023796]", "Set1A, RNA recognition motif [IPR034467]", "Siah interacting protein, N-terminal [IPR015120]", "Sialidase [IPR011040]", "Signal recognition particle SRP54, helical bundle [IPR013822]", "Signal recognition particle receptor, alpha subunit, N-terminal [IPR007222]", "Signal recognition particle subunit SRP68, RNA-binding domain [IPR034652]", "Signal recognition particle, SRP54 subunit, GTPase domain [IPR000897]", "Signal recognition particle, SRP54 subunit, M-domain [IPR004125]", "Signal recognition particle, SRP72 subunit, RNA-binding [IPR013699]", "Signal transducer and activation of transcription 1, TAZ2 binding domain, C-terminal [IPR022752]", "Sin3, C-terminal [IPR031693]", "Sirtuin family, catalytic core domain [IPR026590]", "Sister chromatid cohesion C-terminal domain [IPR024986]", "Ski2, N-terminal domain [IPR040801]", "Sm-like protein Lsm3 [IPR034105]", "Sm-like protein Lsm8 [IPR034103]", "Small G protein signalling modulator 1/2, Rab-binding domain [IPR021935]", "Small GTP-binding protein domain [IPR005225]", "Small acidic protein-like domain [IPR028124]", "Small nuclear ribonucleoprotein D1 [IPR034102]", "Small-subunit processome, Utp12 [IPR007148]", "Small-subunit processome, Utp13 [IPR013934]", "Small-subunit processome, Utp21 [IPR007319]", "Smc1, ATP-binding cassette domain [IPR028468]", "Smc2, ATP-binding cassette domain [IPR027120]", "Snf2, ATP coupling domain [IPR029295]", "Snu114, GTP-binding domain [IPR044121]", "Sof1-like protein [IPR007287]", "Solute carrier family 3 member 2, N-terminal domain [IPR031984]", "Somatomedin B domain [IPR001212]", "Somatomedin B, chordata [IPR020436]", "Sortilin, C-terminal [IPR031777]", "Sortilin, N-terminal [IPR031778]", "Sorting Nexin 1, PX domain [IPR034901]", "Sorting nexin Vps5-like, C-terminal [IPR015404]", "Sorting nexin protein, WASP-binding domain [IPR019497]", "Sorting nexin, N-terminal [IPR005329]", "Sorting nexin-17/31, FERM domain [IPR040842]", "Sorting nexin-9, BAR domain [IPR037425]", "Sorting nexin-9, PX domain [IPR037426]", "Spen paralogue and orthologue SPOC, C-terminal [IPR012921]", "Spen paralogue/orthologue C-terminal, metazoa [IPR010912]", "Spermidine synthase, tetramerisation domain [IPR035246]", "Spindle assembly abnormal protein 6, N-terminal [IPR032396]", "Splicing factor 1, helix-hairpin domain [IPR032570]", "Splicing factor 3A subunit 1, conserved domain [IPR022030]", "Splicing factor 3A subunit 1, ubiquitin domain [IPR035563]", "Splicing factor 3B subunit 1 [IPR015016]", "Splicing factor ELAV/Hu, RNA recognition motif 1 [IPR034775]", "Splicing factor RBM39, linker [IPR029123]", "Splicing factor SF3a60 /Prp9 subunit, C-terminal [IPR024598]", "Splicing factor SF3a60 binding domain [IPR021966]", "Spp2/MOS2, G-patch domain [IPR026822]", "Spt5 C-terminal domain [IPR024945]", "Spt5 transcription elongation factor, N-terminal [IPR022581]", "Spt5, KOW domain repeat 1 [IPR041973]", "Spt5, KOW domain repeat 2 [IPR041975]", "Spt5, KOW domain repeat 3 [IPR041976]", "Spt5, KOW domain repeat 4 [IPR041977]", "Spt5, KOW domain repeat 5 [IPR041978]", "Spt5, KOW domain repeat 6 [IPR041980]", "Spt6 acidic, N-terminal domain [IPR028083]", "Spt6, SH2 domain [IPR035420]", "Spt6, SH2 domain, C terminus [IPR035018]", "Spt6, SH2 domain, N terminus [IPR035019]", "Squalene cyclase, C-terminal [IPR032696]", "Squalene cyclase, N-terminal [IPR032697]", "Squalene epoxidase [IPR013698]", "Srp40, C-terminal [IPR007718]", "StAR-related lipid transfer protein 3, C-terminal [IPR029867]", "Staphylococcal nuclease (SNase-like), OB-fold [IPR016071]", "Staufen 1, third double-stranded RNA binding domain [IPR044475]", "Staufen 2, first double-stranded RNA binding domain [IPR044476]", "Staufen 2, fourth double-stranded RNA binding domain [IPR044474]", "Staufen 2, second double-stranded RNA binding domain [IPR044464]", "Staufen 2, third double-stranded RNA binding domain [IPR044473]", "Staufen, C-terminal [IPR032478]", "Steadiness box (SB) domain [IPR017916]", "Sterile alpha motif domain [IPR001660]", "Sterol-sensing domain [IPR000731]", "Strawberry notch, AAA domain [IPR039187]", "Strawberry notch, helicase C domain [IPR026937]", "Striatin, N-terminal [IPR013258]", "Strictosidine synthase, conserved region [IPR018119]", "Stromalin conservative domain [IPR020839]", "Structural maintenance of chromosomes 3, ABC domain, eukaryotic [IPR041741]", "Structural maintenance of chromosomes 4, ABC domain, eukaryotic [IPR041738]", "Succinate dehydogenase/fumarate reductase N-terminal [IPR025192]", "Sulfatase, N-terminal [IPR000917]", "Sulfatase-modifying factor enzyme [IPR005532]", "Sulfhydryl oxidase, Trx-like domain [IPR041269]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain [IPR040986]", "Sulphate adenylyltransferase [IPR002650]", "Sulphate adenylyltransferase catalytic domain [IPR024951]", "Suppressor of forked [IPR008847]", "Suppressor of white apricot, N-terminal domain [IPR019147]", "Survival motor neuron [IPR010304]", "Suv3, C-terminal domain 1 [IPR041082]", "Suv3, DEXQ-box helicase domain [IPR044774]", "Suv3, N-terminal [IPR041453]", "Symplekin C-terminal [IPR022075]", "Symplekin/Pta1, N-terminal [IPR032460]", "Synaptic functional regulator FMRP, KH0 domain [IPR040472]", "Synaptotagmin, SMP domain [IPR039010]", "Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468]", "Synaptotagmin-like, mitochondrial and lipid-binding domain [IPR040885]", "Synembryn [IPR008376]", "Syntaxin 6, N-terminal [IPR015260]", "Syntaxin, N-terminal domain [IPR006011]", "Syntaxin-5, N-terminal, Sly1p-binding domain [IPR021538]", "Syntaxin-8, SNARE domain [IPR041875]", "TAFH/NHR1 [IPR003894]", "TAFII55 protein, conserved region [IPR006751]", "TAP C-terminal (TAP-C) domain [IPR005637]", "TAR DNA-binding protein 43, N-terminal [IPR041105]", "TATA box binding protein associated factor (TAF) [IPR004823]", "TATA element modulatory factor 1, TATA binding [IPR022091]", "TATA-binding protein interacting (TIP20) [IPR013932]", "TBCE, ubiquitin-like (Ubl) domain [IPR044079]", "TCB1D9/TCB1D9B, PH-GRAM domain 1 [IPR036014]", "TCB1D9/TCB1D9B, PH-GRAM domain 2 [IPR036017]", "TFG box [IPR025768]", "TFG, PB1 domain [IPR034857]", "TFIIEalpha/SarR/Rpc3 HTH domain [IPR024550]", "TFIIF beta subunit, HTH domain [IPR040450]", "TFIIF, beta subunit, N-terminal [IPR040504]", "TGS [IPR004095]", "THADA/TRM732, DUF2428 [IPR019442]", "THIF-type NAD/FAD binding fold [IPR000594]", "THO complex subunit 2, N-terminal domain [IPR032302]", "THO complex, subunitTHOC2, C-terminal [IPR021418]", "THO complex, subunitTHOC2, N-terminal [IPR021726]", "THUMP domain [IPR004114]", "TIA-1, RNA recognition motif 2 [IPR034830]", "TIA-1, RNA recognition motif 3 [IPR034832]", "TIAR, RNA recognition motif 1 [IPR034492]", "TIAR, RNA recognition motif 2 [IPR034494]", "TIAR, RNA recognition motif 3 [IPR034496]", "TIF1-beta, RING finger, HC subclass [IPR042713]", "TIP49, P-loop domain [IPR010339]", "TOG domain [IPR034085]", "TOPK, catalytic domain [IPR041989]", "TOPRIM domain [IPR006171]", "TPX2 central domain [IPR027330]", "TPX2, C-terminal [IPR027329]", "TRAM domain [IPR002792]", "TRAM/LAG1/CLN8 homology domain [IPR006634]", "TRAM1-like protein [IPR013599]", "TRASH domain [IPR011017]", "TRF2-interacting telomeric protein/Rap1, C-terminal [IPR021661]", "TRIAD supradomain [IPR044066]", "TRIM21, PRY/SPRY domain [IPR035831]", "TRIM25, PRY/SPRY domain [IPR042753]", "TRMT2A, RNA recognition motif [IPR034262]", "TROVE domain [IPR008858]", "TSG101 and ALIX binding domain of CEP55 [IPR022008]", "TUG ubiquitin-like domain [IPR021569]", "TUP1-like enhancer of split [IPR011494]", "TUTase nucleotidyltransferase domain [IPR045100]", "Talin, N-terminal F0 domain [IPR032425]", "Talin, central [IPR015224]", "Talin-1/2, rod-segment [IPR037438]", "Tankyrase 1-binding protein, C-terminal [IPR032764]", "Target SNARE coiled-coil homology domain [IPR000727]", "TatSF1-like, RNA recognition motif 1 [IPR034392]", "TauD/TfdA-like domain [IPR003819]", "Telomere length regulation protein, conserved domain [IPR019337]", "Telomere-associated protein Rif1, N-terminal [IPR022031]", "Teneurin intracellular, N-terminal [IPR009471]", "Tensin phosphatase, C2 domain [IPR014020]", "Tensin-type phosphatase domain [IPR029023]", "Tesmin/TSO1-like CXC domain [IPR033467]", "Testin, LIM domain 1 [IPR034958]", "Testin, LIM domain 2 [IPR034959]", "Testin, LIM domain 3 [IPR034960]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain [IPR020631]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain [IPR020630]", "Tetrapyrrole methylase [IPR000878]", "Tetratricopeptide repeat protein 5, OB fold domain [IPR032076]", "Tetratricopeptide repeat-like domain [IPR018704]", "Tetratricopeptide, SHNi-TPR domain [IPR019544]", "Tex protein, YqgF-like domain [IPR032639]", "Tex, S1 domain [IPR044146]", "Tex-like protein, N-terminal [IPR018974]", "Tfc3, extended winged-helix domain [IPR035625]", "Thg1 C-terminal domain [IPR025845]", "Thiamine pyrophosphate enzyme, C-terminal TPP-binding [IPR011766]", "Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain [IPR012001]", "Thiamine pyrophosphate enzyme, central domain [IPR012000]", "Thioesterase [IPR001031]", "Thioesterase domain [IPR006683]", "Thiolase, C-terminal [IPR020617]", "Thiolase, N-terminal [IPR020616]", "Thioredoxin domain [IPR013766]", "Thioredoxin domain-containing protein 17-like domain [IPR010357]", "Thioredoxin-like fold [IPR012336]", "Thioredoxin-related transmembrane protein 2, thioredoxin domain [IPR037463]", "Threonine-tRNA ligase catalytic core domain [IPR033728]", "Threonyl/alanyl tRNA synthetase, SAD [IPR012947]", "Thymidylate kinase-like domain [IPR039430]", "Thymidylate synthase/dCMP hydroxymethylase domain [IPR023451]", "Tim10-like [IPR004217]", "Tim44-like domain [IPR007379]", "Timeless, C-terminal [IPR007725]", "Timeless, N-terminal [IPR006906]", "Toll/interleukin-1 receptor homology (TIR) domain [IPR000157]", "TopBP1, first BRCT domain [IPR044737]", "Topoisomerase I C-terminal domain [IPR025834]", "Tox-GHH domain [IPR028916]", "Trafficking protein particle complex subunit 11 [IPR021773]", "Trafficking protein particle complex subunit 11, C-terminal [IPR025876]", "Trans-isoprenyl diphosphate synthases, head-to-head [IPR033904]", "Transcription elongation factor S-II, central domain [IPR003618]", "Transcription elongation factor Spt6, YqgF domain [IPR028231]", "Transcription elongation factor Spt6, helix-hairpin-helix motif [IPR032706]", "Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type [IPR003617]", "Transcription factor 20, ePHD domain [IPR041972]", "Transcription factor CBF/NF-Y/archaeal histone domain [IPR003958]", "Transcription factor CP2, SAM domain [IPR037599]", "Transcription factor IIIC subunit 5, HTH domain [IPR019136]", "Transcription factor IIIC subunit Tfc1/Sfc1, triple barrel domain [IPR041499]", "Transcription factor IIIC, 90kDa subunit, N-terminal [IPR024761]", "Transcription factor IIIC, putative zinc-finger [IPR024764]", "Transcription factor IIS, N-terminal [IPR017923]", "Transcription factor TFE/TFIIEalpha HTH domain [IPR017919]", "Transcription factor TFIIB, cyclin-like domain [IPR013150]", "Transcription factor TFIIE alpha subunit, C-terminal [IPR021600]", "Transcription initiation factor IIE subunit alpha, N-terminal [IPR002853]", "Transcription initiation factor TFIID component TAF4, C-terminal [IPR007900]", "Transcription termination and cleavage factor, C-terminal domain [IPR026896]", "Transcriptional coactivator p15 (PC4), C-terminal [IPR003173]", "Transcriptional repressor p66, coiled-coil MBD2-interaction domain [IPR032346]", "Transferrin receptor protein 1/2, PA domain [IPR037324]", "Transferrin receptor-like, dimerisation domain [IPR007365]", "Transketolase, C-terminal domain [IPR033248]", "Transketolase, N-terminal [IPR005474]", "Transketolase-like, pyrimidine-binding domain [IPR005475]", "Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain [IPR014038]", "Translation elongation factor EFG/EF2, domain IV [IPR005517]", "Translation elongation factor EFTs/EF1B, dimerisation [IPR014039]", "Translation elongation factor EFTu-like, domain 2 [IPR004161]", "Translation elongation factor EFTu/EF1A, C-terminal [IPR004160]", "Translation elongation factor, IF5A C-terminal [IPR020189]", "Translation initiation factor IF- 2, domain 3 [IPR023115]", "Translation initiation factor IF-2, domain II [IPR044145]", "Translation initiation factor IF2/IF5 domain [IPR002735]", "Translation initiation factor eIF-2B subunit epsilon, N-terminal [IPR035543]", "Translation initiation factor eIF-2B subunit epsilon, W2 domain [IPR044123]", "Translation initiation factor, beta propellor-like domain [IPR013979]", "Translational (tr)-type GTP-binding domain [IPR000795]", "Translationally controlled tumour protein (TCTP) domain [IPR034737]", "Translocon Sec61/SecY, plug domain [IPR019561]", "Transmembrane protein 201, C-terminal [IPR018861]", "Treacle protein domain [IPR003993]", "Tripartite DENN domain [IPR037516]", "Tripeptidyl-peptidase II domain [IPR034051]", "Trm3/ TARBP1, C-terminal [IPR044748]", "TrmE-type guanine nucleotide-binding domain [IPR031168]", "TryX and NRX, thioredoxin domain [IPR045870]", "Tuberin, N-terminal [IPR024584]", "Tuberin-type domain [IPR018515]", "Tubulin binding cofactor C-like domain [IPR012945]", "Tubulin-folding cofactor B, N-terminal ubiquitin-like domain [IPR045172]", "Tubulin-specific chaperone D, C-terminal [IPR022577]", "Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]", "Tubulin/FtsZ, GTPase domain [IPR003008]", "Tudor domain [IPR002999]", "Tuftelin interacting protein, N-terminal domain [IPR022159]", "Tumour suppressor p53-binding protein-1 Tudor domain [IPR015125]", "Tyrosine-protein kinase BAZ1B, bromodomain [IPR037375]", "Tyrosine-protein kinase Lyn, SH2 domain [IPR035852]", "Tyrosine-protein kinase Lyn, SH3 domain [IPR035748]", "Tyrosine-protein kinase Yes, SH3 domain [IPR035751]", "Tyrosine-protein kinase ephrin type A/B receptor-like [IPR011641]", "Tyrosine-protein kinase, catalytic domain [IPR020635]", "Tyrosine-specific protein phosphatase, PTPase domain [IPR000242]", "Tyrosine-specific protein phosphatases domain [IPR000387]", "U-box domain [IPR003613]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 1 [IPR034407]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 2 [IPR034409]", "U1 small nuclear ribonucleoprotein of 70kDa N-terminal [IPR022023]", "U1-C, C2H2-type zinc finger [IPR013085]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 2 [IPR034562]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 1 [IPR034564]", "U2A'/phosphoprotein 32 family A, C-terminal [IPR003603]", "U3 small nucleolar RNA-associated protein 10, N-terminal [IPR022125]", "U3 small nucleolar RNA-associated protein 15, C-terminal [IPR018983]", "UAS [IPR006577]", "UBAC1, UBA domain 1 [IPR041926]", "UBAC1, UBA domain 2 [IPR041927]", "UBX domain [IPR001012]", "UBXN1, UBA domain [IPR041923]", "UDP-N-acetylglucosamine 2-epimerase domain [IPR003331]", "UDP-glucose/GDP-mannose dehydrogenase, C-terminal [IPR014027]", "UDP-glucose/GDP-mannose dehydrogenase, N-terminal [IPR001732]", "UDP-glucose/GDP-mannose dehydrogenase, dimerisation [IPR014026]", "UDP-glucose:glycoprotein glucosyltransferase, thioredoxin-like domain 4 [IPR040525]", "UDP-glucuronate decarboxylase N-terminal [IPR021761]", "UDP-glycosyltransferase family, conserved site [IPR035595]", "UGGT, thioredoxin-like domain 1 [IPR040693]", "UGGT, thioredoxin-like domain 2 [IPR040694]", "UGGT, thioredoxin-like domain 3 [IPR040692]", "UHRF1, tandem tudor domain [IPR021991]", "UNC-45/Cro1/She4, central domain [IPR024660]", "UPF0113, PUA domain [IPR005155]", "UPF0113, pre-PUA domain [IPR040598]", "UPF3 domain [IPR005120]", "UPF3B, RNA recognition motif-like domain [IPR034979]", "USP8 dimerisation domain [IPR015063]", "UVR domain [IPR001943]", "Ubinuclein middle domain [IPR026947]", "Ubiquinol-cytochrome c reductase 8kDa, N-terminal [IPR015248]", "Ubiquinol-cytochrome c reductase, iron-sulphur subunit [IPR006317]", "Ubiquitin E2 variant, N-terminal [IPR008883]", "Ubiquitin carboxyl-terminal hydrolase 47, C-terminal [IPR045578]", "Ubiquitin carboxyl-terminal hydrolase 5, UBA1 domain [IPR041812]", "Ubiquitin carboxyl-terminal hydrolase 7, ICP0-binding domain [IPR024729]", "Ubiquitin carboxyl-terminal hydrolase, C-terminal [IPR029346]", "Ubiquitin conjugation factor E4, core [IPR019474]", "Ubiquitin specific peptidase 1 [IPR033815]", "Ubiquitin specific protease domain [IPR028889]", "Ubiquitin system component CUE [IPR003892]", "Ubiquitin-activating enzyme E1, C-terminal [IPR018965]", "Ubiquitin-activating enzyme E1, FCCH domain [IPR032418]", "Ubiquitin-activating enzyme E1, four-helix bundle [IPR032420]", "Ubiquitin-activating enzyme, SCCH domain [IPR019572]", "Ubiquitin-associated domain [IPR015940]", "Ubiquitin-conjugating enzyme E2 [IPR000608]", "Ubiquitin-like domain [IPR000626]", "Ubiquitin-like domain, USP-type [IPR028135]", "Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain [IPR032353]", "Ubiquitin-specific peptidase 48 [IPR033841]", "Ubiquitin-specific-processing protease 48, Ubl domain [IPR044743]", "Ubiquitin/SUMO-activating enzyme ubiquitin-like domain [IPR028077]", "Ubiquitinyl hydrolase, variant UBP zinc finger [IPR041432]", "Ubiquitinyl hydrolase-L5 [IPR033837]", "Ulp1 protease family, C-terminal catalytic domain [IPR003653]", "Uncharacterised domain CHP00451 [IPR004521]", "Uncharacterised domain NUC130/133, N-terminal [IPR012977]", "Uncharacterised domain NUC173 [IPR012978]", "Uncharacterised domain NUC202 [IPR012980]", "Unconventional myosin-Ie/If, SH3 domain [IPR035507]", "Up-frameshift suppressor 2, C-terminal [IPR007193]", "Upstream-binding protein 1, SAM domain [IPR037600]", "Uroporphyrinogen decarboxylase (URO-D) [IPR000257]", "Uso1/p115-like vesicle tethering protein, C-terminal [IPR006955]", "VASP tetramerisation [IPR014885]", "VHS domain [IPR002014]", "VIP36, lectin domain [IPR035664]", "VPS10 [IPR006581]", "VPS13, repeated coiled region [IPR031642]", "VPS9 domain [IPR003123]", "Vacuolar protein sorting-associated protein 13, C-terminal [IPR031645]", "Vacuolar protein sorting-associated protein 13, SHR-binding domain [IPR009543]", "Vacuolar protein sorting-associated protein 13, second N-terminal domain [IPR031646]", "Vacuolar protein sorting-associated protein 13-like, N-terminal domain [IPR026854]", "Vacuolar protein sorting-associated protein 4, MIT domain [IPR045253]", "Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 1 [IPR019452]", "Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 2 [IPR019453]", "Valyl tRNA synthetase, anticodon-binding domain [IPR033705]", "Vertebrate SNX3, PX domain [IPR042137]", "Vertebrate ubiquitin-conjugating enzyme E2 K, UBA domain [IPR042599]", "Vesicle tethering protein Uso1/P115-like , head domain [IPR006953]", "Vicinal oxygen chelate (VOC) domain [IPR037523]", "Vinculin-binding site-containing domain [IPR015009]", "Virilizer, N-terminal [IPR031801]", "Vitamin B12-dependent methionine synthase, activation domain [IPR004223]", "Vitamin K epoxide reductase [IPR012932]", "Vps4 oligomerisation, C-terminal [IPR015415]", "Vps53-like, N-terminal [IPR007234]", "Vta1, C-terminal [IPR041212]", "Vta1/callose synthase, N-terminal [IPR039431]", "W2 domain [IPR003307]", "WAPL domain [IPR012502]", "WASH complex subunit 4, N-terminal [IPR028191]", "WASH complex subunit 7, C-terminal [IPR028283]", "WASH complex subunit 7, central domain [IPR028282]", "WD repeat protein mio, zinc-ribbon like domain [IPR031488]", "WD repeat-containing protein 18, C-terminal domain [IPR026987]", "WGR domain [IPR008893]", "WH1/EVH1 domain [IPR000697]", "WH2 domain [IPR003124]", "WHEP-TRS domain [IPR000738]", "WHIM1 domain [IPR028942]", "WHIM2 domain [IPR028941]", "WIBG, Mago-binding [IPR015362]", "WSTF/Acf1/Cbp146 [IPR013136]", "WW domain [IPR001202]", "WWE domain [IPR004170]", "Wings apart-like protein, C-terminal [IPR022771]", "Wolframin, EF-hand domain [IPR045460]", "Wolframin, OB-fold domain [IPR045461]", "Wolframin, cysteine-rich domain [IPR045400]", "XPC-binding domain [IPR015360]", "XPG, N-terminal [IPR006085]", "XPG-I domain [IPR006086]", "XRCC1, first (central) BRCT domain [IPR045080]", "XRN2-binding (XTBD) domain [IPR021859]", "Xrn1, D1 domain [IPR040992]", "Xrn1, helical domain [IPR041412]", "YKT6, SNARE motif [IPR045848]", "YTH domain [IPR007275]", "YchF, C-terminal domain [IPR013029]", "YchF, N-terminal [IPR041706]", "YjeF N-terminal domain [IPR004443]", "YqgF/RNase H-like domain [IPR006641]", "Z-binding domain [IPR042371]", "ZAP, helix turn helix N-terminal domain [IPR041360]", "ZAP, zinc finger [IPR040954]", "ZC3H15/TMA46 family, C-terminal [IPR032378]", "ZCRB1, RNA recognition motif [IPR034219]", "ZMYND8/11, PWWP domain [IPR035505]", "ZN598/Hel2, RING finger [IPR041888]", "ZN622/Rei1/Reh1, zinc finger C2H2-type [IPR041661]", "ZO-1, SH3 domain [IPR035597]", "ZO-2, SH3 domain [IPR035598]", "ZU5 domain [IPR000906]", "ZZEF1, zinc finger, ZZ-type [IPR041986]", "Zasp-like motif [IPR006643]", "Zinc finger C2H2 AKAP95-type [IPR034736]", "Zinc finger C2H2-type [IPR013087]", "Zinc finger C2HC RNF-type [IPR034734]", "Zinc finger, A20-type [IPR002653]", "Zinc finger, AN1-type [IPR000058]", "Zinc finger, B-box, chordata [IPR020457]", "Zinc finger, C2H2, LYAR-type [IPR014898]", "Zinc finger, C3HC-like [IPR012935]", "Zinc finger, C3HC4 RING-type [IPR018957]", "Zinc finger, C5HC2-type [IPR004198]", "Zinc finger, CCCH-type [IPR000571]", "Zinc finger, CCHC-type [IPR001878]", "Zinc finger, CHCC-type [IPR019401]", "Zinc finger, CHHC-type [IPR012996]", "Zinc finger, CW-type [IPR011124]", "Zinc finger, CXXC-type [IPR002857]", "Zinc finger, ClpX C4-type [IPR010603]", "Zinc finger, DNA-directed DNA polymerase, family B, alpha [IPR015088]", "Zinc finger, FCS-type [IPR012313]", "Zinc finger, FPG/IleRS-type [IPR010663]", "Zinc finger, FYVE-related [IPR017455]", "Zinc finger, GATA-type [IPR000679]", "Zinc finger, GRF-type [IPR010666]", "Zinc finger, LIM-type [IPR001781]", "Zinc finger, MIZ-type [IPR004181]", "Zinc finger, MYM-type [IPR010507]", "Zinc finger, MYND-type [IPR002893]", "Zinc finger, Mcm10/DnaG-type [IPR015408]", "Zinc finger, PARP-type [IPR001510]", "Zinc finger, PHD-finger [IPR019787]", "Zinc finger, PHD-type [IPR001965]", "Zinc finger, RING-CH-type [IPR011016]", "Zinc finger, RING-type [IPR001841]", "Zinc finger, RanBP2-type [IPR001876]", "Zinc finger, Sec23/Sec24-type [IPR006895]", "Zinc finger, TFIIB-type [IPR013137]", "Zinc finger, TFIIS-type [IPR001222]", "Zinc finger, UBP-type [IPR001607]", "Zinc finger, UBR-type [IPR003126]", "Zinc finger, ZPR1-type [IPR004457]", "Zinc finger, ZZ-type [IPR000433]", "Zinc finger, double-stranded RNA binding [IPR022755]", "Zinc finger, nuclear hormone receptor-type [IPR001628]", "Zinc knuckle CX2CX3GHX4C [IPR025829]", "Zinc ribbon, NADH pyrophosphatase [IPR015376]", "Zinc-finger C2H2-type 11 [IPR041697]", "Zinc-finger CCCH domain [IPR041686]", "Zinc-finger domain of monoamine-oxidase A repressor R1 [IPR018866]", "Zn-dependent metallo-hydrolase, RNA specificity domain [IPR011108]", "cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain [IPR003117]", "cDENN domain [IPR001194]", "cGMP-dependent protein kinase, interacting domain [IPR031775]", "dDENN domain [IPR005112]", "dUTPase, trimeric [IPR033704]", "dUTPase-like [IPR029054]", "eIF3 subunit M, C-terminal helix domain [IPR040750]", "eIF3B, RNA recognition motif [IPR034363]", "eIF3G, RNA recognition motif [IPR034240]", "eIF3h, C-terminal [IPR045810]", "eIF4H, RNA recognition motif [IPR034229]", "eRF1 domain 1/Pelota-like [IPR005140]", "eRF1 domain 2 [IPR005141]", "eRF1 domain 3 [IPR005142]", "hnRNP A0, RNA recognition motif 1 [IPR034801]", "hnRNP A1, RNA recognition motif 1 [IPR034845]", "hnRNP A1, RNA recognition motif 2 [IPR034803]", "hnRNP A2/B1, RNA recognition motif 1 [IPR034486]", "hnRNP A3, RNA recognition motif 1 [IPR034513]", "hnRNP A3, RNA recognition motif 2 [IPR034516]", "hnRNP DL, RNA recognition motif 1 [IPR034847]", "hnRNP-L, RNA recognition motif 1 [IPR035005]", "hnRNP-L, RNA recognition motif 2 [IPR035008]", "hnRNP-L, RNA recognition motif 3 [IPR034816]", "hnRNP-L, RNA recognition motif 4 [IPR034817]", "hnRNPAB, RNA recognition motif 1 [IPR034846]", "hnRNPH3, RNA recognition motif 2 [IPR034970]", "hnRNPH3, RNA recognition motif 3 [IPR034969]", "hnRNPM, RNA recognition motif 3 [IPR034990]", "mRNA decapping enzyme 2 , NUDIX hydrolase domain [IPR044099]", "mRNA decapping protein 2, Box A domain [IPR007722]", "mRNA splicing factor Cwf21 domain [IPR013170]", "mRNA-decapping enzyme, C-terminal [IPR031953]", "p115RhoGEF, RGS domain [IPR037887]", "p21 activated kinase binding domain [IPR033923]", "p21-activated kinase 2, catalytic domain [IPR035064]", "p53 transactivation domain [IPR013872]", "p53, DNA-binding domain [IPR011615]", "p53, tetramerisation domain [IPR010991]", "p54nrb, RNA recognition motif 1 [IPR034552]", "rRNA-processing arch domain [IPR025696]", "snRNP70, RNA recognition motif [IPR034143]", "tRNA methyltransferase TRM10-type domain [IPR028564]", "tRNA methyltransferase TRMD/TRM10-type domain [IPR016009]", "tRNA pseudouridylate synthase B, C-terminal [IPR032819]", "tRNA synthetase, B5-domain [IPR005147]", "tRNA synthetases class I, catalytic domain [IPR032678]", "tRNA(Met) cytidine acetyltransferase TmcA, N-terminal [IPR013562]", "tRNA-binding domain [IPR002547]", "tRNA-guanine(15) transglycosylase-like [IPR002616]", "tRNA/rRNA methyltransferase, SpoU type [IPR001537]", "tRNAHis guanylyltransferase catalytic domain [IPR024956]", "tRNase Z endonuclease [IPR027794]", "uDENN domain [IPR005113]", "v-SNARE, coiled-coil homology domain [IPR042855]", "von Willebrand factor, type A [IPR002035]"], "available_proteins": ["AACS", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABHD10", "ABHD12", "ABHD6", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTN1", "ACTN2", "ACTN4", "ADA", "ADAM17", "ADAM9", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADK", "ADNP", "ADRM1", "ADSL", "AFDN", "AFG3L2", "AGK", "AGL", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALG11", "ALG2", "ALG5", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC2", "ANAPC5", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32B", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APBB1", "APC", "APEH", "APEX1", "APLP2", "APMAP", "APOBEC3C", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARHGAP17", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID2", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL8B", "ARMC10", "ARMCX3", "ARMT1", "ASAH1", "ASCC2", "ASCC3", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATIC", "ATL2", "ATP11C", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "ATP6V1H", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKB", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAP18", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP31", "BCAS3", "BCOR", "BCS1L", "BIRC6", "BLM", "BLVRA", "BMS1", "BOP1", "BPTF", "BRCA1", "BRD2", "BRD3", "BRD4", "BRD7", "BRD8", "BRIX1", "BROX", "BSG", "BTF3", "BTRC", "BUB1B", "BUD23", "BZW1", "BZW2", "C19orf47", "C1orf35", "C2CD2L", "C2CD5", "C3orf58", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALM3", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CAP1", "CAPN1", "CAPN2", "CAPN7", "CAPNS1", "CAPRIN1", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CBL", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC93", "CCDC97", "CCNA2", "CCNB1", "CCNB2", "CD109", "CD2AP", "CD2BP2", "CD47", "CDC20", "CDC23", "CDC34", "CDC37", "CDC42", "CDC5L", "CDC6", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CDKAL1", "CDKN2AIP", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPV", "CEP170", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CGN", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD8", "CHEK2", "CHERP", "CHID1", "CHORDC1", "CHP1", "CHRAC1", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIRBP", "CISD1", "CISD2", "CIZ1", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLCN7", "CLIC1", "CLIC4", "CLINT1", "CLPB", "CLPX", "CLSTN3", "CLTC", "CLU", "CLUH", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNPY2", "COA3", "COIL", "COLEC12", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "COQ8B", "COQ9", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX2", "COX6C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CREB1", "CRKL", "CRYZ", "CRYZL1", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTNNBL1", "CTPS1", "CTPS2", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CWC22", "CWF19L1", "CYB5B", "CYB5D2", "CYB5R3", "CYFIP1", "CYFIP2", "DAGLB", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCP1A", "DCP2", "DCTN1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DDA1", "DDB1", "DDI2", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEK", "DENND4C", "DENR", "DFFA", "DGCR8", "DHCR24", "DHFR", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB4", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNTTIP2", "DOCK7", "DOLPP1", "DPF2", "DPH5", "DPM1", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS3L", "DUSP12", "DUSP3", "DUT", "DVL2", "DYNC1H1", "DYNC2H1", "EARS2", "EBP", "ECE1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFHD1", "EFL1", "EFTUD2", "EGFR", "EHD1", "EHD4", "EHHADH", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B3", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP3", "EMC1", "EMC7", "EMD", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENPP1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPN1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC3", "ERLIN1", "ERLIN2", "ERMP1", "ERP29", "ERP44", "ESF1", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC4", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EYA4", "EZH2", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAHD2A", "FAM129B", "FAM208A", "FAM210B", "FAM3C", "FAM49B", "FAM8A1", "FANCI", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD5", "FDFT1", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNBP1L", "FNBP4", "FNDC3A", "FOXK1", "FOXK2", "FOXRED1", "FSCN1", "FSTL1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GAK", "GALK1", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCN1", "GDAP1", "GEMIN5", "GFM1", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GHITM", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLDC", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA4", "GOLGB1", "GOPC", "GORASP2", "GOT1", "GOT2", "GPAM", "GPAT4", "GPATCH4", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPR89B", "GPRASP2", "GPS1", "GRB2", "GRHPR", "GRSF1", "GRWD1", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F2", "GTF3C1", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GUSB", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDGFL2", "HDLBP", "HEATR1", "HEATR6", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIRA", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HMBS", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGXB4", "HMMR", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK2", "HOXD13", "HP1BP3", "HPRT1", "HPS3", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA4", "HSPA4L", "HSPB1", "HSPBP1", "HSPH1", "HTATIP2", "HTATSF1", "HTRA2", "HUWE1", "IARS", "IARS2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IFT52", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMP4", "IMPDH2", "INA", "INCENP", "INF2", "INTS1", "INTS11", "INTS12", "INTS14", "INTS3", "INTS9", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRS4", "ISCU", "ISOC1", "ISYNA1", "ITCH", "ITGB1", "ITM2B", "ITM2C", "ITPRIP", "IVD", "IWS1", "JMJD6", "KARS", "KAT7", "KCTD12", "KCTD5", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0391", "KIAA1468", "KIF11", "KIF14", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFC1", "KIN", "KMT2A", "KNOP1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LACTB", "LAMB1", "LAMC1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LBR", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LPGAT1", "LRBA", "LRCH2", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRRC47", "LRRC8C", "LRSAM1", "LSG1", "LSM12", "LSM14B", "LSM2", "LSM3", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LYAR", "LYN", "LYPLA1", "LYRM2", "LZIC", "MACF1", "MAD2L1", "MAGED1", "MAGED2", "MAK16", "MAN2A1", "MAN2B1", "MANF", "MAP2K1", "MAP2K4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARK2", "MARK3", "MARS", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBD1", "MBD3", "MCAM", "MCAT", "MCCC1", "MCCC2", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED25", "MEPCE", "METAP1", "METTL13", "MFAP1", "MFF", "MFN1", "MFSD10", "MGME1", "MIA2", "MIA3", "MICU1", "MICU2", "MINDY3", "MIOS", "MIPEP", "MKI67", "MKRN2", "MLEC", "MMAB", "MMS19", "MMS22L", "MOGS", "MON2", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPDZ", "MPHOSPH8", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPRIP", "MPST", "MRC2", "MRE11", "MRM3", "MRPL11", "MRPL12", "MRPL15", "MRPL2", "MRPL24", "MRPL39", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL48", "MRPL58", "MRPL9", "MRPS23", "MRPS25", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTM1", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MTX3", "MUT", "MYCBP2", "MYEF2", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO6", "NAA10", "NAA40", "NAA50", "NACC1", "NAE1", "NAGLU", "NAMPT", "NANS", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCBP1", "NCK1", "NCK2", "NCKIPSD", "NCL", "NCLN", "NCSTN", "NDUFA10", "NDUFA6", "NDUFA8", "NDUFA9", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFE", "NEMF", "NENF", "NES", "NEU1", "NF2", "NFRKB", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIPSNAP3A", "NISCH", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NME3", "NME7", "NMT1", "NNT", "NOA1", "NOB1", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP2", "NOP56", "NOP58", "NOSIP", "NOVA1", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NRBP1", "NRDC", "NRP1", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NTHL1", "NTPCR", "NUB1", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDCD2", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUF2", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP35", "NUP50", "NUP54", "NUP62", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OCIAD1", "OCLN", "OCRL", "OGDH", "OGFOD3", "OGT", "OLA1", "OPA1", "ORC3", "ORC5", "OS9", "OSBP", "OSBPL11", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD7B", "OXA1L", "OXSR1", "P3H1", "P3H3", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PAOX", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PATJ", "PAXBP1", "PBDC1", "PBK", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH19", "PCID2", "PCK2", "PCM1", "PCNA", "PCYOX1", "PDAP1", "PDCD11", "PDCD4", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE4DIP", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDP1", "PDPR", "PDXK", "PDZD11", "PEF1", "PELP1", "PEPD", "PES1", "PEX14", "PFAS", "PFKL", "PFKM", "PFKP", "PGD", "PGLS", "PGM1", "PGM3", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF14", "PHF3", "PHF6", "PHF8", "PHGDH", "PHIP", "PHRF1", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PIR", "PITHD1", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLAA", "PLCG1", "PLD3", "PLD6", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLS1", "PLS3", "PLXNB2", "PMPCA", "PMPCB", "PMS1", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR3A", "POLR3C", "POLRMT", "POMGNT2", "POP1", "POR", "PPAN", "PPAT", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP1R9B", "PPP3CA", "PPP4C", "PPP4R3A", "PPP5C", "PPP6C", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PRELID1", "PREP", "PREPL", "PRKAA1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PWP2", "PWWP2A", "PYCR1", "PYCR2", "PYCR3", "PYM1", "QARS", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABEP1", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RAD21", "RAD23B", "RAD50", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP6", "RBFOX2", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCL1", "RCN1", "RCN2", "RDX", "RECQL", "RECQL4", "RECQL5", "REL", "REPS1", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RICTOR", "RIF1", "RILPL1", "RIOX1", "RIOX2", "RNASEH2A", "RNF114", "RNF14", "RNF20", "RNF219", "RNF40", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL11", "RPL12", "RPL14", "RPL18", "RPL18A", "RPL19", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL30", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPP25L", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS2", "RPS20", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS9", "RPSA", "RPTOR", "RRBP1", "RREB1", "RRM1", "RRP12", "RSF1", "RTCA", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTN4IP1", "RUFY1", "RUVBL1", "RUVBL2", "RXRB", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART3", "SASS6", "SATB2", "SBDS", "SBNO1", "SC5D", "SCAF11", "SCAF4", "SCCPDH", "SCML2", "SCO2", "SCP2", "SCRIB", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEL1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT8", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SETD1A", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGTA", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHC1", "SHCBP1", "SHMT1", "SHMT2", "SIN3A", "SIN3B", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC25A12", "SLC25A13", "SLC25A24", "SLC27A2", "SLC27A4", "SLC38A2", "SLC3A2", "SLC4A1AP", "SLC4A7", "SLC6A15", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLMAP", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMU1", "SNAP23", "SNAP29", "SND1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC25", "SPECC1", "SPECC1L", "SPEN", "SPNS1", "SPPL2A", "SPRYD4", "SPRYD7", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRBD1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAU1", "STAU2", "STIP1", "STK4", "STOM", "STOML2", "STRBP", "STRIP1", "STRN", "STUB1", "STX10", "STX12", "STX18", "STX3", "STX5", "STX6", "STX7", "STX8", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TAF15", "TAF4", "TAF7", "TAGLN2", "TAOK3", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCB", "TBCD", "TBCE", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TDP2", "TDRKH", "TECR", "TELO2", "TENM3", "TERF2IP", "TES", "TEX10", "TFAM", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THADA", "THG1L", "THOC1", "THOC2", "THOC3", "THOP1", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIMELESS", "TIMM13", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TIMM9", "TJP1", "TJP2", "TKT", "TLN1", "TMED1", "TMED10", "TMED2", "TMED5", "TMED9", "TMEM201", "TMEM205", "TMEM97", "TMF1", "TMLHE", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOM1", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOPBP1", "TOX4", "TP53", "TP53BP1", "TP53BP2", "TPBG", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRIT1", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TROVE2", "TRRAP", "TRUB1", "TSC2", "TSFM", "TSG101", "TSR1", "TST", "TSTA3", "TTC4", "TTC5", "TTF2", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWNK", "TXNDC12", "TXNDC16", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UACA", "UBA1", "UBA2", "UBA5", "UBA6", "UBAC1", "UBAP2", "UBAP2L", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBL5", "UBLCP1", "UBN2", "UBP1", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UGDH", "UGGT1", "UGT8", "UHRF1", "UMPS", "UNC119B", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCRC1", "UQCRC2", "UQCRFS1", "URB1", "URB2", "UROD", "USO1", "USP1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP28", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP20", "UTP3", "UTRN", "UXS1", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VASP", "VAT1", "VCP", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VPS13A", "VPS18", "VPS29", "VPS37B", "VPS4A", "VPS51", "VPS53", "VRK1", "VRK2", "VTA1", "WAPL", "WARS", "WASF2", "WASHC4", "WBP2", "WDHD1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR36", "WDR43", "WDR46", "WFS1", "WIZ", "WNK1", "WNK3", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YBX1", "YES1", "YKT6", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM2", "ZMYM3", "ZMYM4", "ZMYND8", "ZNF207", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF598", "ZNF622", "ZNF638", "ZNF687", "ZPR1", "ZRANB2", "ZYX", "ZZEF1"], "leading_proteins": ["ABCE1", "ACOX1", "ACTN1", "ACTN2", "ADD1", "ADD3", "AFDN", "AFG3L2", "AIMP1", "AKT1", "AKT2", "ALDH1B1", "ALDH3A2", "ALG11", "ANKLE2", "AP3M1", "APEH", "ASCC2", "ATAD3B", "ATP13A1", "ATP1A1", "ATP2A2", "ATP5B", "AUP1", "BAG6", "CALM3", "CALU", "CAND2", "CARS", "CASK", "CCNA2", "CCNB2", "CDKAL1", "CERS2", "CETN2", "CHD3", "CHRAC1", "CIRBP", "CNNM4", "COPG2", "COPS2", "COPS4", "COPS5", "COPS7A", "COPS8", "CPT2", "CSE1L", "CTPS2", "CWC22", "CYB5B", "CYB5D2", "DCUN1D4", "DHCR24", "DIAPH3", "DLG1", "DNAJA2", "DNAJC1", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DVL2", "EBP", "EEA1", "EHD4", "EIF3F", "EIF3H", "EIF3L", "ENDOD1", "ERAP1", "ERBIN", "ERCC3", "ESYT2", "EWSR1", "EXOSC2", "EZR", "FAF1", "FAM49B", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP7", "FKBP9", "FLAD1", "FMR1", "FNBP1L", "FUBP1", "FUBP3", "FUS", "FXR2", "GALNT1", "GALNT2", "GGA2", "GOLGA4", "GOPC", "GPD2", "GPS1", "GTF2B", "HDDC2", "HDGF", "HGS", "HNRNPAB", "HNRNPF", "HNRNPH1", "HNRNPK", "HTRA2", "IGF2BP2", "INA", "INF2", "IPO4", "IPO5", "IPO7", "IPO9", "KDM1A", "KDM1B", "KHDRBS1", "KHDRBS3", "KHSRP", "KIF1B", "KMT2A", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "LBR", "LEMD3", "LMNA", "LMNB2", "LYRM2", "MAPRE2", "MCM3", "MCM4", "MCM7", "MFN1", "MICU1", "MICU2", "MORF4L1", "MPP1", "MPP2", "MPP5", "MPP6", "MRC2", "MSH2", "MSH6", "MSMO1", "MTX1", "MYH10", "MYH14", "MYH9", "NDUFA6", "NECAP1", "NEFL", "NEFM", "NENF", "NES", "NFRKB", "NISCH", "NOVA2", "NPEPPS", "NSUN5", "NUB1", "NUCB2", "OGFOD3", "OPA1", "OTUD7B", "P3H1", "P3H3", "P4HA1", "PABPC1", "PAFAH1B2", "PAIP1", "PAIP2", "PAK2", "PANK4", "PATJ", "PCID2", "PDLIM1", "PHF6", "PITRM1", "PKN2", "PNPLA6", "PPOX", "PRKAR1A", "PRRC2A", "PRRC2C", "PSAP", "PSMC1", "PSMC3", "PSMC5", "PSMC6", "PSMD11", "PSMD13", "PSMD14", "PSMD3", "PSMD7", "PSME1", "PSME3", "PSPC1", "PTPRF", "PUF60", "QKI", "RABGAP1", "RAPGEF2", "RBM10", "RBM3", "RBMX", "RCN2", "REPS1", "RHOT2", "RNF14", "ROCK2", "RPS6KA1", "RTN3", "RTN4", "SDHB", "SEC23B", "SEL1L", "SEPT2", "SEPT6", "SFPQ", "SIN3B", "SMARCC2", "SMC3", "SNAP29", "SNX2", "SNX27", "SNX5", "SNX6", "SPTAN1", "SPTBN1", "SPTBN2", "SQSTM1", "SRSF4", "SSRP1", "STARD3", "STX3", "STX6", "STX7", "STXBP4", "SUN1", "SYNCRIP", "SYNGR2", "SYNJ2BP", "TAF15", "TDRKH", "THOP1", "THUMPD1", "TIMM8A", "TIMM8B", "TIMM9", "TJP1", "TJP2", "TMED10", "TMED2", "TMED5", "TMED9", "TNPO1", "TOP3A", "TPP2", "TRIM21", "TRIM26", "TSTA3", "TUBB", "TUBB2A", "TUBB3", "TUBB4B", "TUBB6", "UBE4B", "UBLCP1", "UBQLN1", "UBXN1", "UBXN7", "UPF1", "UQCRC2", "USP15", "USP47", "VIM", "YTHDC2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAZ", "ZADH2"]} \ No newline at end of file diff --git a/interpro_family/advanced/idx2term.json b/interpro_family/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9fac97e6154138783f939dc931f0fc8139f6a2cd --- /dev/null +++ b/interpro_family/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Proteasome B-type subunit [IPR023333]", "1": "Proteasome, subunit alpha/beta [IPR001353]"} \ No newline at end of file diff --git a/interpro_family/advanced/plot_0.png b/interpro_family/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..0e7b6829fa04938901e183ec67c031cb926c53e1 --- /dev/null +++ b/interpro_family/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3c0bdf384865191e9560f45a5f5b250dc7123202319691b521826653b530c188 +size 182740 diff --git a/interpro_family/advanced/plot_1.png b/interpro_family/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..7e919634fe0541d834681e0a9ff41775fa6638dd --- /dev/null +++ b/interpro_family/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:225e97f94a9b90591fd906cf56af35e214d0b1c20ffbdf72364d7f1e82974e0d +size 191440 diff --git a/interpro_family/basic/idx2term.json b/interpro_family/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..39190bbcc87ea39df6fb265f59451f74da3d1c5f --- /dev/null +++ b/interpro_family/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Proteasome B-type subunit [IPR023333]", "1": "Proteasome, subunit alpha/beta [IPR001353]", "2": "14-3-3 protein [IPR000308]", "3": "Beta tubulin [IPR002453]", "4": "Tubulin [IPR000217]"} \ No newline at end of file diff --git a/interpro_family/basic/plot_0.png b/interpro_family/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..1c035f63e822fc18ccd9e02b9377f07ef7121a30 --- /dev/null +++ b/interpro_family/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:33800c8cb48283d4734673de65572f84b77cf5614ca119b0dce3f01fa70b954d +size 137971 diff --git a/interpro_family/basic/plot_1.png b/interpro_family/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..422a9b4113eab50d7ec6c8e294adaa28ca1ea77a --- /dev/null +++ b/interpro_family/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3bf34bc75c3c2252fedc8160825245572028b269c8cec378ec71c0b257f86785 +size 137717 diff --git a/interpro_family/basic/plot_2.png b/interpro_family/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..cdb2a729c4cf0d8e0bb57b0a10f783d0fa0bbaa1 --- /dev/null +++ b/interpro_family/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e3e0daeb36f394b5f28b521eb83613d0f6908c19d61c7b8ec1e0220ae65bd40b +size 132117 diff --git a/interpro_family/basic/plot_3.png b/interpro_family/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..4d26097f290f74855a989276e03db50fff6fb406 --- /dev/null +++ b/interpro_family/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bd60970cae7665e78b9672ef535f260e91d3d02a7614e8773d45e9c087c26b89 +size 129295 diff --git a/interpro_family/basic/plot_4.png b/interpro_family/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..8846dbe0b54a2fb55cb9e75f8adc7f57dac90083 --- /dev/null +++ b/interpro_family/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3a20e0168fa5358a51c5787924251d77a424b5aaa8c9ceb3d02c1eb6873e8c16 +size 126526 diff --git a/interpro_family/consensus.joblib b/interpro_family/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..e53623bb5b9c824fc0d34affd487b65c8c45f55e --- /dev/null +++ b/interpro_family/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fc7e2be5a694c7b397bae6d30bc789aec6a04801eaddeb0abc3495674c7ca8a0 +size 176536 diff --git a/interpro_family/df_merge.tsv b/interpro_family/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..ec28a061d3c4e184fe018bbb0f0da7e60c838681 --- /dev/null +++ b/interpro_family/df_merge.tsv @@ -0,0 +1,6 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Proteasome B-type subunit [IPR023333] 5 7 2.3837050511536773 0.0171393330701299 3.699029126213592 6.970873786407767 1.6670727234653664 0.1509307531330224 1.4503762582219135 0.1681602725795027 0.9611878160538336 0.233503072382129 0.1051177798435183 0.0424464003246627 0.0832836732680532 0.0010713621736615 9.6474859037805e-07 +Protein arginine N-methyltransferase [IPR025799] 2 5 2.191818606765328 0.0283926070319291 2.0825242718446604 4.550970873786408 0.3373673127581389 0.5030561866515755 1.3997175293723505 0.5070608522549612 0.967000381893454 0.3222502577912521 1.0 1.0 1.0 0.014977467250991 0.0053637976870067 +Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930] 2 6 2.1463745148665527 0.0318431109160448 2.121359223300971 5.466019417475728 1.4317001483019938 0.1783942022754649 1.021530403905949 0.5881604361499402 0.986353205880356 0.2226891741813114 9.631703469408072e-05 0.0006219606051344 0.002465796513642 0.0007272762906085 0.0053637976870067 +P-type ATPase [IPR001757] 3 6 2.0877925802438866 0.0368165491671925 2.941747572815534 6.145631067961165 0.9567723497044874 0.2732808833570771 1.8358630293390923 1.459204245106796 1.2102525517005158 0.2943240638910574 0.237888308904226 1.0 0.191600110602388 0.0990342687178565 0.2914565107291916 +Proteasome, subunit alpha/beta [IPR001353] 5 14 2.0430725681993915 0.0410452549776225 5.075242718446602 13.970873786407768 1.2284854682369022 0.3020132543529001 2.3027355385508845 0.1681602725795027 1.1101966392985694 0.3179790146746512 0.1792312731033967 0.0742352733278267 0.1432798584585485 0.0062969264366488 6.856302599535404e-05 diff --git a/interpro_family/metrics.json b/interpro_family/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..d023a9cf66792940ef1ea9d1d1fd4764323f460a --- /dev/null +++ b/interpro_family/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3381, + "annotations_size": 2585, + "title": "Average number of proteins per term", + "value": 1.2893617021276595 +} \ No newline at end of file diff --git a/interpro_family/paths.json b/interpro_family/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..d3f71695a54949e34bd09959650e14c86f93fe23 --- /dev/null +++ b/interpro_family/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_family/fragment/C317/C317_val_log2fc"} \ No newline at end of file diff --git a/interpro_family/result.tsv b/interpro_family/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..df8955a36c844ebcf2bd8e5580689c5c42b1febd --- /dev/null +++ b/interpro_family/result.tsv @@ -0,0 +1,122 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Proteasome B-type subunit [IPR023333] 0.8341973934608833 2.3837050511536773 0.0171393330701299 1.0 0.4717945838061802 7 P28072,P28070,P28074,P20618,P49721 5 +Protein arginine N-methyltransferase [IPR025799] 0.8620574314535382 2.1918186067653274 0.0283926070319291 1.0 0.4717945838061802 5 O60678,Q6P2P2 2 +Aminopeptidase N-type [IPR034016] 0.9137320926448362 2.1710243290303475 0.0299293333590646 1.0 0.4717945838061802 4 P55786,Q9NZ08 2 +Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930] 0.8007907825564105 2.1463745148665527 0.0318431109160448 1.0 0.4717945838061802 6 P55786,Q9NZ08 2 +Nucleosome assembly protein (NAP) [IPR002164] 0.9029238200973716 2.128446346774769 0.0333000939386578 1.0 0.4717945838061802 4 Q99733,Q01105 2 +P-type ATPase [IPR001757] 0.7874198459158005 2.0877925802438866 0.0368165491671925 1.0 0.4717945838061802 6 P16615,Q9HD20,P05023 3 +Proteasome, subunit alpha/beta [IPR001353] 0.6303578366844339 2.0430725681993915 0.0410452549776225 1.0 0.4717945838061802 14 P28072,P28070,P28074,P20618,P49721 5 +TAF15/EWS/TLS family [IPR034870] 0.928063943161634 1.853100633235392 0.063867936096893 1.0 0.4717945838061802 3 Q92804,P35637 2 +Eukaryotic porin/Tom40 [IPR027246] 0.8192732781313572 1.7929083967093338 0.0729875725068085 1.0 0.4717945838061802 4 P21796 1 +Tropomyosin [IPR000533] 0.8949082297217278 1.7248135649126015 0.0845610763465507 1.0 0.483644241182545 3 P67936,P09493 2 +Peptidase T1A, proteasome beta-subunit [IPR000243] 0.8931320307874475 1.7179119606358662 0.0858126748678345 1.0 0.483644241182545 3 P28072,P28074 2 +KH domain-containing BBP-like [IPR045071] 0.7979880625038029 1.705967414790937 0.0880141466689385 1.0 0.4854522204726738 4 O75525,Q96PU8 2 +Porin, eukaryotic type [IPR001925] 0.8793568974967896 1.664296804904495 0.0960531306116037 1.0 0.48579884142232 3 P21796 1 +Transmembrane emp24 domain-containing protein [IPR015720] 0.7226106016172062 1.600415845645378 0.1095063621928398 1.0 0.5036339622273746 5 Q15363,Q9BVK6,P49755 3 +Proteasome activator PA28 [IPR009077] 0.8626406157489638 1.599037263341476 0.1098123230513268 1.0 0.5036339622273746 3 P61289,Q06323 2 +Mitochondrial inner membrane translocase complex, subunit Tim17 [IPR005678] 0.994968925717668 1.585416284895544 0.1128717835775938 1.0 0.5087372588859259 2 O60830 1 +Haem oxygenase [IPR002051] 0.979875702870672 1.526265966042433 0.1269436409309055 1.0 0.5216457634559135 2 P30519 1 +Haem oxygenase-like [IPR016053] 0.979875702870672 1.526265966042433 0.1269436409309055 1.0 0.5216457634559135 2 P30519 1 +ATPase, V0 complex, subunit 116kDa, eukaryotic [IPR026028] 0.9783959751405742 1.5204657796257754 0.12839395301713 1.0 0.5216457634559135 2 Q93050 1 +V-type ATPase, V0 complex, 116kDa subunit family [IPR002490] 0.9783959751405742 1.5204657796257754 0.12839395301713 1.0 0.5216457634559135 2 Q93050 1 +ER lumen protein retaining receptor [IPR000133] 0.9778040840485354 1.5181456840203085 0.128977676662283 1.0 0.5217641536338052 2 P24390 1 +Mpv17/PMP22 [IPR007248] 0.9704054453980472 1.489144470719462 0.1364493295257127 1.0 0.5282292905876393 2 Q9NR77 1 +Cytochrome P450 [IPR001128] 0.9668540988458127 1.4752246949561592 0.1401521443249371 1.0 0.5282292905876393 2 Q16850 1 +Sulfotransferase [IPR005331] 0.9659662622077538 1.4717449198877162 0.1410897724681217 1.0 0.5282292905876393 2 Q8NCH0 1 +Mitochondrial carrier UCP-like [IPR002030] 0.964782480023676 1.4671053512597492 0.1423473986561965 1.0 0.5282292905876393 2 Q9H2D1 1 +Nonaspanin (TM9SF) [IPR004240] 0.8134991119005301 1.4062874711612967 0.1596387789838642 1.0 0.5449698737469258 3 Q99805,Q9HD45 2 +Peptidase M3A/M3B [IPR045090] 0.8132826930791204 1.4054367519629034 0.1598914445259014 1.0 0.5449698737469258 3 P52888 1 +Calcium uptake protein 1/2/3 [IPR039800] 0.9482095294465818 1.402178115154798 0.1608620651168979 1.0 0.5450824722518355 2 Q9BPX6 1 +Dynamin [IPR022812] 0.8043220840734048 1.370208340387232 0.1706218755165061 1.0 0.5560424410117405 3 O60313,O00429 2 +Peroxisomal acyl-coenzyme A oxidase [IPR034171] 0.9375554897898792 1.3604828966946798 0.1736771616115391 1.0 0.5563264718287839 2 Q15067 1 +Acyl-CoA oxidase [IPR012258] 0.9375554897898792 1.3604828966946798 0.1736771616115391 1.0 0.5563264718287839 2 Q15067 1 +Transmembrane protein GPR107/GPR108-like [IPR009637] 0.9337081976916256 1.3454385784606353 0.178483643952203 1.0 0.5619734709091899 2 Q5VW38 1 +Glutathione Transferase family [IPR040079] 0.5460511651416607 1.338426660497492 0.1807573928764627 1.0 0.5642656678884688 11 Q13505 1 +Defective-in-cullin neddylation protein [IPR014764] 0.7832355418367575 1.287309501660783 0.1979864330638243 1.0 0.5886924115901824 3 Q92564 1 +Mitochondrial import inner membrane translocase subunit Tim8/13 [IPR039238] 0.7797513321491921 1.2736189698294051 0.2027984860023355 1.0 0.5933835442503548 3 Q9Y5J9,O60220 2 +Glycoside hydrolase family 47 [IPR001382] 0.9121041728322 1.2611289750727577 0.2072623827693578 1.0 0.5972946036329877 2 P33908 1 +Prolyl 3-hydroxylase [IPR039575] 0.9112163361941404 1.25767175703538 0.2085104904246089 1.0 0.5981035082140183 2 Q8IVL6 1 +Golgi phosphoprotein 3-like [IPR008628] 0.910032554010063 1.253063221984021 0.2101826992800524 1.0 0.5981035082140183 2 Q9H4A5 1 +Ezrin/radixin/moesin [IPR011174] 0.6758933909543849 1.1994282806875558 0.2303614564510954 1.0 0.6113802514641495 4 P15311 1 +Bcl2-like [IPR002475] 0.7557726465364101 1.179540084647218 0.2381831849518092 1.0 0.6169374079162594 3 Q07820,Q9BXK5 2 +Bcl-2 family [IPR026298] 0.7557726465364101 1.179540084647218 0.2381831849518092 1.0 0.6169374079162594 3 Q07820,Q9BXK5 2 +Syntaxin [IPR045242] 0.5742408721245376 1.1701957620424108 0.2419221979156198 1.0 0.6185646702392457 7 O43752,Q13277 2 +Mini-chromosome maintenance protein [IPR031327] 0.5796766122654664 1.13703945625699 0.2555217917010539 1.0 0.6307133418683759 6 P33993,P33991,P25205 3 +Cleft lip and palate transmembrane 1 [IPR008429] 0.8694880142053876 1.0961954970502852 0.2729932297950799 1.0 0.643288513236355 2 O96005 1 +Cleft lip and palate transmembrane protein 1-like protein [IPR030434] 0.8694880142053876 1.0961954970502852 0.2729932297950799 1.0 0.643288513236355 2 O96005 1 +Prefoldin beta-like [IPR002777] 0.8668245042912117 1.0859737195412795 0.2774906194847997 1.0 0.6491522636816355 2 O15212 1 +Spectrin, beta subunit [IPR016343] 0.8517312814442155 1.028302326983879 0.3038076368077007 1.0 0.6718073063711774 2 Q01082 1 +Structural maintenance of chromosomes protein [IPR024704] 0.6315976303291175 1.01539975609011 0.309915309283999 1.0 0.6773293120306055 4 Q9UQE7 1 +Sorting nexin-5/6/32 [IPR014637] 0.8342704942290635 0.9622025429309896 0.3359478720185667 1.0 0.6985506902007353 2 Q9Y5X3 1 +Fragile X mental retardation syndrome-related protein [IPR040148] 0.6865008880994583 0.9112632098962014 0.3621567060231196 1.0 0.7216015258174088 3 P51116,Q06787 2 +TB2/DP1/HVA22-related protein [IPR004345] 0.684132622853759 0.9022500198432908 0.3669240690721054 1.0 0.7268507461423944 3 Q00765,Q9H6H4 2 +E3 ubiquitin ligase Bre1 [IPR013956] 0.8117786327315795 0.8782601693102041 0.3798025458667304 1.0 0.736749850917906 2 Q5VTR2 1 +HnRNP R/Q splicing factor [IPR006535] 0.8108907960935208 0.8749786513954669 0.3815855218026578 1.0 0.7372186650671678 2 O60506 1 +Chaperone tailless complex polypeptide 1 (TCP-1) [IPR017998] 0.5019419612935798 0.8740619031974802 0.3820845430240627 1.0 0.7376314740233025 8 P49368,P78371 2 +E3 ubiquitin ligase RBR family [IPR031127] 0.8088191772713842 0.86733204922752 0.3857601012661633 1.0 0.7389016935470553 2 Q9UBS8 1 +ATPase family AAA domain-containing protein 3 [IPR039188] 0.8082272861793453 0.8651499779465964 0.3869564765701208 1.0 0.7393070893819381 2 Q5T9A4 1 +CTP synthase [IPR004468] 0.8058597218111889 0.8564337632965269 0.3917578958091612 1.0 0.7435346260401481 2 Q9NRF8 1 +Glycosyl transferase, family 8 [IPR002495] 0.8046759396271108 0.8520829949355011 0.3941680294757672 1.0 0.745918269542356 2 Q68CQ7 1 +Tumour protein D52 [IPR007327] 0.7946137910624469 0.8153077159604155 0.4148961931982948 1.0 0.7638009702495102 2 P55327 1 +SCAMP [IPR007273] 0.6569473837422223 0.7999435928499452 0.4237434792539443 1.0 0.7679249813391175 3 O15126 1 +SUN domain-containing protein 1-5 [IPR045119] 0.7863273157738999 0.78531659690185 0.4322679672197951 1.0 0.7759579581138035 2 O94901 1 +Small GTPase superfamily, SAR1-type [IPR006687] 0.7750813850251581 0.7450789655507867 0.4562239842375613 1.0 0.793248203609995 2 Q9NR31 1 +Ancient conserved domain protein family [IPR045095] 0.7676827463746698 0.7189220415577485 0.4721889547863378 1.0 0.8072807196578593 2 Q6P4Q7 1 +Ribosomal protein S6 kinase II [IPR016239] 0.7611719443622403 0.6961257886688488 0.4863500575484782 1.0 0.8195664268336482 2 Q15418 1 +Prolyl 4-hydroxylase [IPR045054] 0.7502219591595178 0.6582872503540936 0.510353569001595 1.0 0.8355060011837385 2 P13674 1 +Importin beta family [IPR040122] 0.5023895923940925 0.6430714948475029 0.5201777097616314 1.0 0.8435755205356443 5 O00410,Q92973 2 +Peptidase, FtsH [IPR005936] 0.7312814442142681 0.5944646562431976 0.5522013748598091 1.0 0.8606230100338155 2 Q9Y4W6 1 +GDP-fucose protein O-fucosyltransferase [IPR019378] 0.7203314590115457 0.5586061871365009 0.5764305165316084 1.0 0.8747576255635251 2 Q9Y2G5 1 +RNA (C5-cytosine) methyltransferase [IPR023267] 0.5787435369579625 0.5234590698483411 0.6006548269897884 1.0 0.8922479107485325 3 Q96P11 1 +Purine 5'-nucleotidase [IPR016695] 0.7007990529742567 0.4967555846758902 0.6193614196845465 1.0 0.9017527399051536 2 Q9H857 1 +Rho-associated protein kinase 1/2 [IPR020684] 0.6889612311334757 0.4607101509576802 0.6450065712237312 1.0 0.912346990289894 2 O75116 1 +Microtubule-associated protein RP/EB [IPR027328] 0.6827463746670656 0.4422541215343804 0.6583053259749272 1.0 0.917973386550712 2 Q15555 1 +ClpA/B family [IPR001270] 0.6720923350103626 0.4114044627568978 0.6807759820845114 1.0 0.9313809720701672 2 Q9H078 1 +Septin [IPR016491] 0.408656824530983 0.3798189900549192 0.7040797848587546 1.0 0.94323081423749 6 Q15019,Q14141 2 +Dynein 1 light intermediate chain [IPR008467] 0.6549274933412301 0.3639218434788334 0.7159163727450826 1.0 0.94323081423749 2 Q9Y6G9 1 +Dynein family light intermediate chain [IPR022780] 0.6549274933412301 0.3639218434788334 0.7159163727450826 1.0 0.94323081423749 2 Q9Y6G9 1 +Twinfilin [IPR028458] 0.6519680378810349 0.3560254449994301 0.7218215096888572 1.0 0.9452470850331072 2 Q6IBS0 1 +Polyadenylate binding protein, human types 1, 2, 3, 4 [IPR006515] 0.631251849659668 0.3032784546711575 0.7616776641424075 1.0 0.956269393859328 2 P11940 1 +14-3-3 protein [IPR000308] 0.3869629629629664 0.2995852009527869 0.7644935739050567 1.0 0.956269393859328 6 Q04917,P31946,P62258,P63104,P61981 5 +Tight junction protein ZO [IPR005417] 0.627996448653453 0.2954051570845331 0.767684394215238 1.0 0.956269393859328 2 Q9UDY2 1 +Plakophilin/Delta catenin [IPR028435] 0.5000000000000181 0.290553569769204 0.7713927746099503 1.0 0.956269393859328 3 O00192,Q99959 2 +26S proteasome regulatory subunit Rpn7/COP9 signalosome complex subunit 1 [IPR019585] 0.6241491565551992 0.2862503335749545 0.7746863951902947 1.0 0.956269393859328 2 Q13098 1 +cAMP-dependent protein kinase regulatory subunit [IPR012198] 0.6229653743711212 0.2834664212033291 0.7768193184672998 1.0 0.956269393859328 2 P10644 1 +Mitogen-activated protein (MAP) kinase, ERK1/2 [IPR008349] 0.6226694288251016 0.2827728786802313 0.7773509458392995 1.0 0.956269393859328 2 P27361 1 +Phosphatidyl serine synthase [IPR004277] 0.6203018644569455 0.2772597352391765 0.7815806746162972 1.0 0.956269393859328 2 Q9BVG9 1 +Coatomer gamma subunit [IPR017106] 0.6143829535365548 0.2637527111985298 0.7919704755239125 1.0 0.956269393859328 2 Q9UBF2 1 +Vinculin/alpha-catenin [IPR006077] 0.4748371817643755 0.2300142585683863 0.8180806900113489 1.0 0.956269393859328 3 Q9UBT7,P18206 2 +Chaperonin Cpn60/GroEL/TCP-1 family [IPR002423] 0.3534214246528337 0.2298717233549226 0.8181914494730469 1.0 0.956269393859328 9 P49368 1 +CPSF6/7 family [IPR034772] 0.5918910920390708 0.2161042854178734 0.828906459359934 1.0 0.956269393859328 2 Q8N684 1 +Mrp/NBP35 ATP-binding protein [IPR019591] 0.5859721811186802 0.2045531843398846 0.8379212353638541 1.0 0.956269393859328 2 Q8TB37 1 +Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 [IPR033756] 0.5859721811186802 0.2045531843398846 0.8379212353638541 1.0 0.956269393859328 2 Q8TB37 1 +Protein PRRC2 [IPR033184] 0.4567791592658496 0.1914361974536589 0.8481838629780865 1.0 0.956269393859328 3 P48634,Q9Y520 2 +Acyltransferase ChoActase/COT/CPT [IPR000542] 0.5788694880142116 0.1912432352868524 0.8483350318161604 1.0 0.956269393859328 2 P23786 1 +Importin subunit alpha [IPR024931] 0.3729265402843499 0.1896812876005828 0.8495588849304507 1.0 0.956269393859328 5 P52292,O00505,O60684,O00629 4 +Erlin1/2 [IPR033294] 0.5688073394495476 0.1734219138790937 0.8623198012877449 1.0 0.956269393859328 2 O94905 1 +Derlin [IPR007599] 0.5634803196211962 0.1644787953091622 0.8693542382989867 1.0 0.956269393859328 2 Q9GZP9 1 +HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase [IPR008380] 0.4425402191974058 0.1640097245030701 0.8697234884312137 1.0 0.956269393859328 3 Q9H857 1 +Beta tubulin [IPR002453] 0.3407407407407445 0.1526431394111993 0.8786797032852867 1.0 0.956269393859328 6 P68371,P07437,Q13509,Q13885,Q9BUF5 5 +Tubulin [IPR000217] 0.3407407407407445 0.1526431394111993 0.8786797032852867 1.0 0.956269393859328 6 P68371,P07437,Q13509,Q13885,Q9BUF5 5 +THRAP3/BCLAF1 family [IPR029199] 0.5501627700503176 0.1436053815442815 0.8858120908519269 1.0 0.956269393859328 2 Q9NYF8 1 +Small GTPase superfamily, ARF/SAR type [IPR006689] 0.3255984161971249 0.1300470001273935 0.8965292416741433 1.0 0.956269393859328 9 Q8N8L6 1 +Acidic leucine-rich nuclear phosphoprotein 32 [IPR045081] 0.5347736016573019 0.1220953263817263 0.902823523195284 1.0 0.9573741502625074 2 Q92688 1 +Pyridine nucleotide-disulphide oxidoreductase, class I [IPR001100] 0.5297425273749701 0.1156589872579603 0.9079228114693124 1.0 0.9583423714365752 2 P00390 1 +Microtubule associated protein 1 [IPR026074] 0.403493191237416 0.1025568480674539 0.9183146924339728 1.0 0.9613764566209396 3 P78559,Q66K74 2 +NSF attachment protein [IPR000744] 0.5051790470553492 0.0882867242543513 0.9296487902617454 1.0 0.9641163223299511 2 P54920 1 +Heterogeneous nuclear ribonucleoprotein C [IPR017347] 0.502811482687193 0.0859909104091104 0.9314736429043176 1.0 0.9641163223299511 2 P07910 1 +Transcriptional regulatory protein Sin3-like [IPR039774] 0.4664101805267909 0.0575543175853827 0.9541036386009228 1.0 0.9729222508021244 2 O75182 1 +DNA mismatch repair MutS family [IPR045076] 0.3472468916518666 0.0473956159747511 0.9621979230409584 1.0 0.978474284445664 3 P43246,P52701 2 +Initiation factor 4G [IPR045208] 0.3357015985790352 0.0402646091047752 0.9678821687283528 1.0 0.9823560304765826 3 Q04637,P78344 2 +Taxilin family [IPR026183] 0.4072210713228832 0.0332861122324179 0.973446428456956 1.0 0.9864206262490126 2 P40222 1 +Translin family [IPR002848] 0.3974548683042403 0.0311461354528491 0.9751529967291828 1.0 0.9871077966271374 2 Q99598 1 +Prefoldin alpha-like [IPR004127] 0.3962710861201608 0.0309133199621741 0.9753386672069164 1.0 0.9871077966271374 2 Q99471 1 +Cullin-associated NEDD8-dissociated protein 1/2 [IPR039852] 0.3956791950281224 0.0307989521226123 0.9754298761099188 1.0 0.9871077966271374 2 O75155 1 +Prenylated rab acceptor PRA1 [IPR004895] 0.3873927197395764 0.0293338102917996 0.9765983617841744 1.0 0.9872924384873254 2 O75915 1 +Cysteine-tRNA ligase [IPR015803] 0.3794021899970495 0.0281419791519046 0.9775489127983288 1.0 0.987481023674748 2 P49589 1 +Cysteinyl-tRNA synthetase/mycothiol ligase [IPR024909] 0.3794021899970495 0.0281419791519046 0.9775489127983288 1.0 0.987481023674748 2 P49589 1 +MRG [IPR008676] 0.3649008582420934 0.0264496899122258 0.9788986611769032 1.0 0.988312399205923 2 Q9UBU8 1 +Mitochondrial Rho GTPase [IPR021181] 0.3551346552234472 0.0255941438188427 0.9795810570971076 1.0 0.988312399205923 2 Q8IXI1 1 +Cyclin [IPR039361] 0.2933688573120138 0.0232780043850806 0.981428516917612 1.0 0.988312399205923 3 O95067,P20248 2 +Sodium/potassium-transporting ATPase subunit beta [IPR000402] 0.2920982539212871 0.0232754764519879 0.9814305333700596 1.0 0.988312399205923 2 P05026 1 +Snf7 family [IPR005024] 0.2815614906877854 0.0157960519513373 0.9873970981312844 1.0 0.9920021370654372 7 O43633 1 diff --git a/interpro_family/selections.json b/interpro_family/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..37f699ec5b66f5169dca94c55fc0836e2a7ac7a6 --- /dev/null +++ b/interpro_family/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["(Uracil-5)-methyltransferase family [IPR010280]", "1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, eukaryotes [IPR027496]", "1-Cys peroxiredoxin [IPR045020]", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [IPR028380]", "14-3-3 protein [IPR000308]", "14-3-3 theta [IPR042584]", "18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23-like [IPR039769]", "2-amino-3-ketobutyrate coenzyme A ligase [IPR011282]", "2-deoxynucleoside 5-phosphate N-hydrolase 1, DNPH1 [IPR028607]", "2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3 [IPR039210]", "2-oxoglutarate dehydrogenase E1 component [IPR011603]", "2-phosphoglycolate phosphatase, eukaryotic [IPR006349]", "26S Proteasome non-ATPase regulatory subunit 1 [IPR035266]", "26S Proteasome non-ATPase regulatory subunit 11 [IPR035295]", "26S Proteasome non-ATPase regulatory subunit 12 [IPR035297]", "26S Proteasome non-ATPase regulatory subunit 12/COP9 signalosome complex subunit 4 [IPR040134]", "26S Proteasome non-ATPase regulatory subunit 13 [IPR035298]", "26S Proteasome non-ATPase regulatory subunit 14 [IPR035299]", "26S Proteasome non-ATPase regulatory subunit 6 [IPR035268]", "26S Proteasome non-ATPase regulatory subunit 7/8 [IPR033858]", "26S Proteasome regulatory subunit 4 [IPR035244]", "26S Proteasome regulatory subunit 6A [IPR035254]", "26S Proteasome regulatory subunit 6B [IPR035256]", "26S Proteasome regulatory subunit 7 [IPR035245]", "26S proteasome non-ATPase regulatory subunit 10-like [IPR039334]", "26S proteasome non-ATPase regulatory subunit 3 [IPR035267]", "26S proteasome non-ATPase regulatory subunit Rpn12 [IPR006746]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit [IPR016643]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit [IPR016642]", "26S proteasome regulatory subunit 10B [IPR035263]", "26S proteasome regulatory subunit P45-like [IPR005937]", "26S proteasome regulatory subunit Rpn7/COP9 signalosome complex subunit 1 [IPR019585]", "28S ribosomal protein S17, mitochondrial [IPR039193]", "28S ribosomal protein S25, mitochondrial [IPR040049]", "28S ribosomal protein S27, mitochondrial [IPR019266]", "28kDa heat- and acid-stable phosphoprotein [IPR039876]", "3'-5' RNA helicase YTHDC2-like [IPR031083]", "3-hydroxyacyl-CoA dehydrogenase [IPR022694]", "3-hydroxyisobutyrate dehydrogenase [IPR011548]", "3-hydroxyisobutyrate dehydrogenase-related [IPR015815]", "3-ketodihydrosphingosine reductase KDSR-like [IPR045022]", "3-oxo-5-alpha-steroid 4-dehydrogenase/very-long-chain enoyl-CoA reductase [IPR039357]", "39S ribosomal protein L40, mitochondrial [IPR039145]", "39S ribosomal protein L43/54S ribosomal protein L51 [IPR039927]", "39S ribosomal protein L46, mitochondrial [IPR040008]", "4-aminobutyrate aminotransferase, eukaryotic [IPR004631]", "40S Ribosomal protein S10 [IPR037447]", "40S ribosomal protein S1/3, eukaryotes [IPR027500]", "40S ribosomal protein S29/30S ribosomal protein S14 type Z [IPR039744]", "40S ribosomal protein SA [IPR027504]", "4F2 cell-surface antigen heavy chain [IPR042280]", "5'-3' exoribonuclease 1 [IPR016494]", "5'-3' exoribonuclease [IPR027073]", "5'-3' exoribonuclease type 2 [IPR017151]", "5'-AMP-activated protein kinase subunit gamma-1 [IPR039166]", "5'-deoxynucleotidase YfbR/HDDC2 [IPR039356]", "5-formyltetrahydrofolate cyclo-ligase [IPR002698]", "5-lipoxygenase-activating protein [IPR001446]", "50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a [IPR028877]", "6-Phosphogluconolactonase [IPR039104]", "6-phosphogluconate dehydrogenase [IPR006183]", "6-phosphogluconate dehydrogenase, decarboxylating [IPR006113]", "60S acidic ribosomal protein P0 [IPR030670]", "60S ribosomal protein L18a/ L20, eukaryotes [IPR021138]", "60S ribosomal protein L19 [IPR039547]", "60S ribosomal protein L35 [IPR045059]", "60S ribosomal protein L6E [IPR000915]", "60kDa SS-A/Ro ribonucleoprotein [IPR040322]", "A-kinase anchor protein 12 [IPR028540]", "A-kinase anchor protein 13 [IPR028852]", "A-kinase anchor protein 17A [IPR034355]", "A-kinase anchor protein 9/Pericentrin [IPR028745]", "A-kinase anchoring protein 95 (AKAP95) [IPR007071]", "A1 cistron-splicing factor, AAR2 [IPR007946]", "AAA ATPase, CDC48 family [IPR005938]", "ABC transporter Tap-like [IPR013305]", "ABT1/Esf2 [IPR039119]", "ADF/Cofilin [IPR017904]", "ADP-ribosylation factor 1-5 [IPR045872]", "ADP-ribosylation factor 6 [IPR041838]", "ADP-ribosylation factor-like protein 10 [IPR042951]", "ADP-ribosylation factor-like protein 2 [IPR045873]", "ADP-ribosylation factor-like protein 2/3 [IPR044612]", "ADP-ribosylation factor-like protein 6-interacting protein 1 [IPR033301]", "ADP-ribosylation factor-like protein 8A/8B [IPR044154]", "ADP-ribosylation/Crystallin J1 [IPR005502]", "ADP-specific phosphofructokinase/glucokinase [IPR007666]", "ADP/ATP carrier protein, eukaryotic type [IPR002113]", "AH receptor-interacting protein [IPR031208]", "AIP/AIPL1 [IPR039663]", "ALG11 mannosyltransferase [IPR038013]", "AMP deaminase 2 [IPR029749]", "AMP deaminase [IPR006329]", "AP complex subunit beta [IPR026739]", "AP endonuclease 1 [IPR004808]", "AP-1/2/4 complex subunit beta [IPR016342]", "AP-2 complex subunit sigma [IPR027156]", "AP-3 complex subunit beta [IPR026740]", "AP-3 complex subunit sigma [IPR027155]", "ARMET-like [IPR045333]", "ATP synthase membrane subunit K [IPR009125]", "ATP synthase subunit ATP5MJ, mitochondrial [IPR012574]", "ATP synthase, F0 complex, subunit A [IPR000568]", "ATP synthase, F0 complex, subunit A, bacterial/mitochondria [IPR045083]", "ATP synthase, F0 complex, subunit B [IPR013837]", "ATP synthase, F0 complex, subunit B/MI25 [IPR008688]", "ATP synthase, F0 complex, subunit D, mitochondrial [IPR008689]", "ATP synthase, F0 complex, subunit E, mitochondrial [IPR008386]", "ATP synthase, F0 complex, subunit G, mitochondrial [IPR006808]", "ATP synthase, F1 complex, alpha subunit [IPR005294]", "ATP synthase, F1 complex, beta subunit [IPR005722]", "ATP synthase, F1 complex, gamma subunit [IPR000131]", "ATP-binding cassette subfamily B member 10-like [IPR030260]", "ATP-citrate synthase [IPR014608]", "ATP-dependent 6-phosphofructokinase [IPR022953]", "ATP-dependent 6-phosphofructokinase, eukaryotic-type [IPR009161]", "ATP-dependent 6-phosphofructokinase, vertebrate-type [IPR041914]", "ATP-dependent Clp protease proteolytic subunit [IPR001907]", "ATP-dependent RNA helicase DHX29 [IPR034730]", "ATP-dependent RNA helicase Ski2-like [IPR016438]", "ATP-dependent helicase Rad3/Chl1-like [IPR013020]", "ATP11 [IPR010591]", "ATP12, ATP synthase F1-assembly protein [IPR011419]", "ATP:cob(I)alamin adenosyltransferase, PduO-type [IPR029499]", "ATP:guanido phosphotransferase [IPR000749]", "ATPase family AAA domain-containing protein 2 [IPR031252]", "ATPase family AAA domain-containing protein 3 [IPR039188]", "ATPase family AAA domain-containing protein ATAD2-like [IPR045199]", "ATPase, OSCP/delta subunit [IPR000711]", "ATPase, V0 complex, c/d subunit [IPR002843]", "ATPase, V0 complex, subunit 116kDa, eukaryotic [IPR026028]", "ATPase, V0 complex, subunit d [IPR016727]", "ATPase, V1 complex, subunit A [IPR005725]", "ATPase, V1 complex, subunit B [IPR005723]", "ATPase, V1 complex, subunit C [IPR004907]", "ATPase, V1 complex, subunit D [IPR002699]", "ATPase, V1 complex, subunit H [IPR004908]", "ATPase, vacuolar ER assembly factor, Vma12 [IPR021013]", "Acetoacetyl-CoA synthase [IPR005914]", "Acid ceramidase-like [IPR016699]", "Acidic leucine-rich nuclear phosphoprotein 32 [IPR045081]", "Acireductone dioxygenase ARD family [IPR004313]", "Aconitase, mitochondrial-like [IPR006248]", "Aconitase/Iron-responsive element-binding protein 2 [IPR006249]", "Actin family [IPR004000]", "Actin-related protein 10 [IPR027127]", "Actin-related protein 2/3 complex subunit 1 [IPR017383]", "Actin-related protein 2/3 complex subunit 1A [IPR030140]", "Actin-related protein 2/3 complex subunit 2 [IPR007188]", "Actin-related protein 2/3 complex subunit 3 [IPR007204]", "Actin-related protein 2/3 complex subunit 4 [IPR008384]", "Actin-related protein 3 [IPR015623]", "Actin-related protein 6 [IPR030054]", "Activator of 90kDa heat shock protein ATPase-like [IPR039981]", "Activator of Hsp90 ATPase homologue 1-like [IPR013538]", "Active regulator of SIRT1 [IPR023262]", "Active zone protein ELKS [IPR019323]", "Activity-dependent neuroprotector homeobox protein [IPR038861]", "Acyl-CoA desaturase [IPR015876]", "Acyl-CoA oxidase [IPR012258]", "Acyl-CoA thioesterase [IPR003703]", "Acyl-CoA-binding domain-containing protein 5 [IPR016347]", "Acyl-coenzyme A thioesterase 13 [IPR039298]", "Acylneuraminate cytidylyltransferase [IPR003329]", "Acyltransferase ChoActase/COT/CPT [IPR000542]", "Adaptor protein Cbl [IPR024162]", "Adaptor protein complex AP-1, gamma subunit [IPR017107]", "Adaptor protein complex AP-2, alpha subunit [IPR017104]", "Adaptor protein complex AP-3, delta subunit [IPR017105]", "Adaptor protein complex, sigma subunit [IPR016635]", "Adenine phosphoribosyl transferase [IPR005764]", "Adenomatous polyposis coli (APC) family [IPR026818]", "Adenomatous polyposis coli [IPR026836]", "Adenosine deaminase [IPR028893]", "Adenosine kinase [IPR001805]", "Adenosine/adenine deaminase [IPR006330]", "Adenosylhomocysteinase-like [IPR000043]", "Adenylate cyclase-associated CAP [IPR001837]", "Adenylate kinase 2 [IPR028587]", "Adenylate kinase 3/4, mitochondrial [IPR028586]", "Adenylate kinase 4, mitochondrial [IPR028585]", "Adenylate kinase isoenzyme 1 [IPR028582]", "Adenylate kinase isoenzyme 6 [IPR020618]", "Adenylate kinase subfamily [IPR006259]", "Adenylate kinase, isozyme 1/5 [IPR006267]", "Adenylate kinase/UMP-CMP kinase [IPR000850]", "Adenylosuccinate lyase [IPR004769]", "Adenylosuccinate synthetase [IPR001114]", "Adenylosuccinate synthetase isozyme 2, chordates [IPR027529]", "Adenylyl cyclase-associated protein CAP1 [IPR028415]", "Adenylyl-sulfate kinase [IPR002891]", "AdoMet-dependent rRNA methyltransferase Spb1-like [IPR028589]", "Aladin [IPR045139]", "Alanine-tRNA ligase, class IIc [IPR002318]", "Alanine-tRNA ligase, eukaryota/bacteria [IPR023033]", "Alcohol dehydrogenase class III [IPR014183]", "Aldehyde dehydrogenase NAD(P)-dependent [IPR012394]", "Aldehyde dehydrogenase family 7 member A1-like [IPR044638]", "Aldo-keto reductase [IPR020471]", "Aldo-keto reductase family 1 member A1 [IPR044481]", "Aldose 1-/Glucose-6-phosphate 1-epimerase [IPR008183]", "Aldose 1-epimerase [IPR015443]", "Alkyldihydroxyacetonephosphate synthase [IPR025650]", "Alpha E-catenin/Alpha T-catenin [IPR030047]", "Alpha crystallin/Small heat shock protein, animal type [IPR001436]", "Alpha-2-macroglobulin receptor-associated protein [IPR038003]", "Alpha-D-phosphohexomutase superfamily [IPR005841]", "Alpha-L-fucosidase, metazoa-type [IPR016286]", "Alpha-N-acetylglucosaminidase [IPR007781]", "Alpha-N-methyltransferase NTM1 [IPR008576]", "Alpha-adducin [IPR027766]", "Alpha-catenin [IPR001033]", "Alpha-catulin 1 [IPR030045]", "Alpha-internexin [IPR027703]", "Alpha-ketoglutarate-dependent dioxygenase FTO [IPR032868]", "Amidase [IPR000120]", "Amidophosphoribosyltransferase [IPR005854]", "Amino acid/polyamine transporter I [IPR002293]", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 [IPR042360]", "Aminoacyl-tRNA synthetase, class Ic [IPR002305]", "Aminopeptidase N-type [IPR034016]", "Aminopeptidase, leukotriene A4 hydrolase-like [IPR034015]", "Aminotransferase class IV [IPR001544]", "Aminotransferase class-III [IPR005814]", "AmpG-like permease/Acetyl-coenzyme A transporter 1 [IPR004752]", "Amyloid beta precursor protein binding family B member 1/2/3 [IPR039576]", "Amyloid-beta precursor protein [IPR028866]", "Amyloidogenic glycoprotein [IPR008155]", "Anamorsin [IPR007785]", "Anaphase-promoting complex subunit 1 [IPR024990]", "Anaphase-promoting complex subunit 16 [IPR029641]", "Anaphase-promoting complex subunit 2 [IPR044554]", "Anaphase-promoting complex subunit 5 [IPR037679]", "Ancient conserved domain protein family [IPR045095]", "Angiomotin [IPR009114]", "Ankycorbin [IPR042420]", "Ankyrin repeat and LEM domain-containing protein 2 [IPR035007]", "Annexin A1 [IPR002388]", "Annexin A11 [IPR008157]", "Annexin A2 [IPR002389]", "Annexin A6 [IPR002393]", "Annexin [IPR001464]", "Anoctamin [IPR007632]", "Anoctamin-6 [IPR031295]", "Antifreeze, type III [IPR006013]", "Antigen peptide transporter 1 [IPR013306]", "Antigen peptide transporter 2 [IPR005293]", "Apolipoprotein L [IPR008405]", "Apoptosis inhibitory 5 [IPR008383]", "Apoptosis regulator BAX [IPR026304]", "Apoptosis regulator, Mcl-1 [IPR013281]", "Apyrase [IPR009283]", "Arfaptin family [IPR030798]", "Arfaptin-1 [IPR030793]", "Arginase [IPR014033]", "Arginine-tRNA ligase [IPR001278]", "Armadillo repeat protein deleted in velo-cardio-facial syndrome [IPR028444]", "Armadillo repeat-containing protein 6 [IPR040104]", "Armadillo-type fold containing protein ARMC8/Vid28 [IPR038739]", "Arsenical pump ATPase, ArsA/GET3 [IPR016300]", "Arsenical pump ATPase, ArsA/GET3, eukaryotic [IPR027542]", "Arylesterase [IPR002640]", "Asparagine synthase, glutamine-hydrolyzing [IPR006426]", "Asparagine-tRNA ligase [IPR004522]", "Asparaginyl endopeptidase [IPR043577]", "Aspartate carbamoyltransferase [IPR002082]", "Aspartate-tRNA ligase, type 1 [IPR004524]", "Aspartate-tRNA synthetase, type 2 [IPR004523]", "Aspartate/ornithine carbamoyltransferase [IPR006130]", "Aspartate/other aminotransferase [IPR000796]", "Aspartyl/Asparaginyl-tRNA synthetase, class IIb [IPR002312]", "Aspartyl/asparaginyl beta-hydroxylase family [IPR039038]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit [IPR004413]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, subunit B /E [IPR017959]", "Associate of Myc 1 [IPR026060]", "Ataxin2-like [IPR045117]", "Atypical dual specificity phosphatase, subfamily A [IPR020405]", "Atypical kinase COQ8A [IPR034640]", "Atypical kinase COQ8B [IPR034638]", "Aurora kinase B [IPR028772]", "Aurora kinase [IPR030616]", "Autophagy protein Atg8 ubiquitin-like [IPR004241]", "Autophagy-related protein 9 [IPR007241]", "B-cell receptor-associated protein 29/31 [IPR008417]", "BBP/SF1 family [IPR031150]", "BCAS3-like [IPR045142]", "BCP1 family [IPR025602]", "BLOC-2 complex, Hps6 subunit [IPR017218]", "BRCA1-A complex subunit BRE [IPR010358]", "BRCA1-associated [IPR031099]", "BRI3-binding protein [IPR033367]", "BRISC and BRCA1-A complex member 1 [IPR026126]", "BRO1 domain-containing protein BROX [IPR038898]", "BTB-kelch protein [IPR017096]", "Bacterial/eukaryotic lysine-tRNA ligase, class II [IPR034762]", "Baculoviral IAP repeat-containing protein 6 [IPR022103]", "Band 4.1 protein, chordates [IPR021187]", "Band 4.1-like protein 2 [IPR030546]", "Band 4.1-like protein 3 [IPR030691]", "Band-7 stomatin-like [IPR043202]", "Barrier- to-autointegration factor, BAF [IPR004122]", "Basigin [IPR044157]", "Basigin-like [IPR043204]", "Bax inhibitor 1-related [IPR006214]", "Bcl-2 family [IPR026298]", "Bcl-2-associated transcription factor 1 [IPR026668]", "Bcl-2-like protein 13 [IPR042398]", "Bcl2-like [IPR002475]", "Beta tubulin [IPR002453]", "Beta-1,4-glucuronyltransferase 1 [IPR043189]", "Beta-N-acetylglucosaminidase [IPR011496]", "Beta-adducin [IPR027773]", "Beta-catenin [IPR013284]", "Beta-catenin-like protein 1 [IPR039678]", "Beta-galactosidase 1-like [IPR026283]", "Beta-hexosaminidase [IPR025705]", "Beta-lactamase HcpB-like [IPR040239]", "Bicarbonate transporter, eukaryotic [IPR003020]", "Bicaudal-D protein [IPR018477]", "Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66 [IPR013109]", "Bifunctional polynucleotide phosphatase/kinase PNKP [IPR006550]", "Bifunctional purine biosynthesis protein PurH-like [IPR002695]", "Biliverdin reductase A [IPR017094]", "Biotin--acetyl-CoA-carboxylase ligase [IPR004408]", "BolA protein [IPR002634]", "BolA-like protein 2 [IPR045115]", "Brain acid soluble protein 1 [IPR008408]", "Branched-chain amino acid aminotransferase II [IPR005786]", "Branched-chain aminotransferase [IPR033939]", "Breast cancer type 1 susceptibility protein (BRCA1) [IPR011364]", "Bromodomain adjacent to zinc finger domain protein 2A [IPR028940]", "Bromodomain-containing protein 8 [IPR038002]", "Bud22/Serum response factor-binding protein 1 [IPR037393]", "Bystin [IPR007955]", "C-5 cytosine methyltransferase [IPR001525]", "C-terminal binding protein [IPR043322]", "C2 domain-containing protein 2-like [IPR039934]", "C2 domain-containing protein 5 [IPR038983]", "CAAX prenyl protease 1 [IPR027057]", "CCR4-NOT transcription complex subunit 1 [IPR040398]", "CCR4-NOT transcription complex subunit 10 [IPR039740]", "CCR4-NOT transcription complex subunit 11 [IPR019312]", "CCR4-NOT transcription complex subunit 7 [IPR039636]", "CCR4-NOT transcription complex subunit 7/8/Pop2 [IPR039637]", "CCR4-NOT transcription complex subunit 9 [IPR007216]", "CD166 antigen [IPR039810]", "CD2 antigen cytoplasmic tail-binding protein 2/Lin1 [IPR039905]", "CD2-associated protein [IPR028445]", "CD36 family [IPR002159]", "CD36/scavenger receptor class B member 1 [IPR005428]", "CDC45 family [IPR003874]", "CDC50/LEM3 family [IPR005045]", "CDCA7/CDA7L [IPR040221]", "CDGSH iron-sulfur domain-containing protein 1/2 [IPR045131]", "CDK5 regulatory subunit-associated protein 3 [IPR008491]", "CEBPZ/Mak21-like [IPR040155]", "CGG triplet repeat-binding protein 1 [IPR033375]", "CHORD domain containing protein [IPR039790]", "CLIP-associating protein 1 [IPR028399]", "CLU domain containing protein [IPR027523]", "COMPASS component Swd2/WDR82 [IPR037867]", "COP9 Signalosome complex subunit 7A [IPR037757]", "COP9 signalosome complex subunit 1 [IPR033008]", "COP9 signalosome complex subunit 2 [IPR037750]", "COP9 signalosome complex subunit 3 [IPR037753]", "COP9 signalosome complex subunit 4 [IPR037754]", "COP9 signalosome complex subunit 5 [IPR037740]", "COP9 signalosome subunit 6 [IPR033859]", "COP9 signalosome, subunit CSN8 [IPR033205]", "COPII coat assembly protein, Sec16 [IPR024880]", "CPSF6/7 family [IPR034772]", "CTP synthase [IPR004468]", "CWF11 family [IPR026300]", "CXXC motif containing zinc binding protein, eukaryotic [IPR008584]", "CYFIP-related Rac1 interactor [IPR039789]", "Cadherin [IPR039808]", "Calcium homeostasis endoplasmic reticulum protein [IPR039037]", "Calcium load-activated calcium channel [IPR008559]", "Calcium uptake protein 1/2/3 [IPR039800]", "Calcium-binding mitochondrial carrier protein Aralar2 [IPR029658]", "Calcium-binding protein CAB45 [IPR027240]", "Calcium-transporting ATPase type 2C member 1 [IPR030336]", "Caldesmon [IPR006017]", "Caldesmon/lymphocyte specific protein [IPR006018]", "Calpain small subunit 1 [IPR029642]", "Calpain-1 [IPR029643]", "Calpain-2 [IPR029539]", "Calpastatin [IPR026998]", "Calponin-2 [IPR029974]", "Calponin/LIMCH1 [IPR001997]", "Calreticulin [IPR009169]", "Calreticulin/calnexin [IPR001580]", "Calsyntenin [IPR026914]", "Calumenin [IPR027239]", "Caprin [IPR028816]", "Carbamoyl-phosphate synthase, large subunit [IPR006275]", "Carbamoyl-phosphate synthase, small subunit [IPR006274]", "Carbohydrate sulfotransferase 8-10 [IPR018011]", "Cartilage-associated protein [IPR033212]", "Casein Kinase 2, subunit alpha [IPR045216]", "Casein kinase II, regulatory subunit [IPR000704]", "Cat eye syndrome critical region protein 5 [IPR029621]", "Catechol O-methyltransferase, eukaryotic [IPR017128]", "Catenin delta-1 [IPR028439]", "Cation efflux protein [IPR002524]", "Cationic amino acid transport permease [IPR004755]", "Ccdc97-like [IPR018613]", "Cdc37 [IPR004918]", "Cdc42 [IPR037874]", "Cdc73/Parafibromin [IPR007852]", "Cell cycle and apoptosis regulator protein 2 [IPR028811]", "Cell cycle and apoptosis regulator protein [IPR025224]", "Cell cycle control protein 50A [IPR030351]", "Cell cycle regulator Mat89Bb [IPR019355]", "Cell division cycle-associated 7-like protein [IPR033578]", "Cell division cycle-associated protein 2 [IPR033064]", "Cell division protein Cdc6/18 [IPR016314]", "Cell division protein borealin [IPR018867]", "Cell growth-regulating nucleolar protein [IPR039999]", "Cell-cycle alteration and expression-elevated protein in tumour [IPR032337]", "Cellular repressor of E1A-stimulated genes (CREG) [IPR014631]", "Centrin 2 [IPR037629]", "Centrosomal protein of 135kDa [IPR026732]", "Centrosomal protein of 170kDa [IPR026644]", "Centrosomal protein of 55kDa [IPR038926]", "Ceramide glucosyltransferase [IPR025993]", "Cerebellar degeneration-related protein 2 [IPR026079]", "Ceroid-lipofuscinosis neuronal protein 5 [IPR026138]", "Cgr1-like [IPR005579]", "Chaperone DnaJ [IPR012724]", "Chaperone DnaK [IPR012725]", "Chaperone tailless complex polypeptide 1 (TCP-1) [IPR017998]", "Chaperonin Cpn60/GroEL [IPR001844]", "Chaperonin Cpn60/GroEL/TCP-1 family [IPR002423]", "Charged multivesicular body protein 1a [IPR029888]", "Chitobiosyldiphosphodolichol beta-mannosyltransferase ALG1-like [IPR026051]", "Chloride channel CLIC-like [IPR009231]", "Chloride channel ClC-3 [IPR002245]", "Chloride channel ClC-7 [IPR002249]", "Chloride channel, voltage gated [IPR001807]", "Chloride intracellular channel protein 1 [IPR030259]", "Chloride intracellular channel protein 4/6 [IPR030257]", "Chromatid cohesion factor MAU2 [IPR019440]", "Chromatin assembly factor 1 subunit A [IPR022043]", "Chromatin assembly factor 1 subunit Cac2/CHAF1B/FAS2 [IPR045145]", "Chromatin complexes subunit BAP18 [IPR037931]", "Chromatin modification-related protein Eaf6 [IPR015418]", "Chromatin modification-related protein Eaf7/MRGBP [IPR012423]", "Chromatin-remodeling complex component Sfh1/SNF5 [IPR017393]", "Chromobox protein homolog 2 [IPR042796]", "Chromobox protein homologue 3 [IPR038033]", "Chromodomain-helicase-DNA-binding protein 1-like [IPR031053]", "Chromodomain-helicase-DNA-binding protein 8 [IPR034724]", "Chromosome alignment-maintaining phosphoprotein 1 [IPR039330]", "Cilia- and flagella-associated protein 20/CFAP20DC [IPR040441]", "Cip1-interacting zinc finger protein [IPR026811]", "Citrate synthase [IPR002020]", "Citrate synthase, eukaryotic-type [IPR010109]", "Class I-like SAM-dependent O-methyltransferase [IPR002935]", "Clathrin adaptor, mu subunit [IPR001392]", "Clathrin coat assembly protein AP180-like [IPR045192]", "Clathrin interactor 1 [IPR030544]", "Clathrin light chain [IPR000996]", "Clathrin, heavy chain [IPR016341]", "Cleavage and polyadenylation specificity factor subunit 2 [IPR027075]", "Cleavage and polyadenylation specificity factor subunit 6 [IPR034769]", "Cleavage and polyadenylation specificity factor subunit 7 [IPR034770]", "Cleavage stimulation factor subunit 1-like [IPR044633]", "Cleavage stimulation factor subunit 2 [IPR033105]", "Cleavage/polyadenylation specificity factor subunit 5 [IPR016706]", "Cleft lip and palate transmembrane 1 [IPR008429]", "Cleft lip and palate transmembrane protein 1-like protein [IPR030434]", "Clp protease proteolytic subunit /Translocation-enhancing protein TepA [IPR023562]", "Clp protease, ATP-binding subunit ClpX [IPR004487]", "ClpA/B family [IPR001270]", "Clusterin [IPR016016]", "Clusterin-like [IPR000753]", "Co-chaperone protein p23-like [IPR045250]", "Coactosin-like protein [IPR030502]", "Coatomer alpha subunit [IPR016391]", "Coatomer beta subunit (COPB1) [IPR016460]", "Coatomer beta' subunit (COPB2) [IPR016453]", "Coatomer delta subunit [IPR027059]", "Coatomer gamma subunit [IPR017106]", "Coatomer subunit zeta [IPR039652]", "Coatomer, epsilon subunit [IPR006822]", "Cobalamin-dependent methionine synthase [IPR011822]", "Cofactor of BRCA1 [IPR010405]", "Cofilin 1 [IPR027234]", "Cohesin subunit Scc3/SA [IPR039662]", "Coiled-coil domain-containing protein 124/Oxs1 [IPR010422]", "Coiled-coil domain-containing protein 127 [IPR034607]", "Coiled-coil domain-containing protein 134 [IPR026321]", "Coiled-coil domain-containing protein 138 [IPR038798]", "Coiled-coil domain-containing protein 22 [IPR008530]", "Coiled-coil domain-containing protein 86 [IPR026570]", "Coiled-coil domain-containing protein 93 [IPR039116]", "Coilin [IPR024822]", "Condensin complex subunit 2/barren [IPR022816]", "Condensin complex subunit 3 [IPR027165]", "Condensin subunit 1 [IPR007673]", "Condensin subunit 1/Condensin-2 complex subunit D3 [IPR026971]", "Condensin-2 complex subunit D3 [IPR012371]", "Conserved oligomeric Golgi complex subunit 7 [IPR019335]", "Conserved oligomeric Golgi complex, subunit 3 [IPR007265]", "Constitutive coactivator of PPAR-gamma [IPR026784]", "Copine [IPR045052]", "Copper chaperone SCO1/SenC [IPR003782]", "Coproporphyrinogen III oxidase, aerobic [IPR001260]", "Core histone macro-H2A [IPR021171]", "Coronin 1B [IPR027340]", "Coronin 1C [IPR027333]", "Coronin 7 [IPR027331]", "Coronin [IPR015505]", "Cortactin [IPR015503]", "Csn12 family [IPR045114]", "Cullin [IPR045093]", "Cullin-4B [IPR033044]", "Cullin-7 [IPR031223]", "Cullin-associated NEDD8-dissociated protein 1/2 [IPR039852]", "Cwf19-like protein [IPR040194]", "Cyclic nucleotide phosphodiesterase [IPR008431]", "Cyclin [IPR039361]", "Cyclin-dependent kinase 6 [IPR028788]", "Cyclophilin-RNA interacting protein [IPR035542]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase [IPR024936]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, cyclophilin A-like [IPR044666]", "Cys/Met metabolism, pyridoxal phosphate-dependent enzyme [IPR000277]", "Cysteine desulfurase IscS [IPR010240]", "Cysteine desulfurase [IPR016454]", "Cysteine protease ATG4B, metazoa [IPR032916]", "Cysteine-tRNA ligase [IPR015803]", "Cysteinyl-tRNA synthetase/mycothiol ligase [IPR024909]", "Cystinyl aminopeptidase [IPR034017]", "Cytochrome B561-related [IPR019176]", "Cytochrome P450 [IPR001128]", "Cytochrome P450, E-class, group I [IPR002401]", "Cytochrome P450, E-class, group IV [IPR002403]", "Cytochrome b-c1 complex subunit 7 [IPR003197]", "Cytochrome b-c1 complex subunit 8 [IPR004205]", "Cytochrome b-c1 complex subunit 9 [IPR008027]", "Cytochrome c oxidase assembly factor 3, mitochondrial [IPR041752]", "Cytochrome c oxidase subunit 6C [IPR004204]", "Cytochrome c oxidase subunit IV [IPR013288]", "Cytochrome c oxidase subunit IV family [IPR004203]", "Cytochrome c oxidase subunit VII [IPR039297]", "Cytochrome c oxidase subunit VIIa, metazoa [IPR003177]", "Cytochrome c oxidase subunit VIIa-related, mitochondrial [IPR017267]", "Cytochrome c oxidase subunit VIIc [IPR004202]", "Cytochrome c oxidase, subunit Va/VI [IPR003204]", "Cytochrome c oxidase, subunit Vb [IPR002124]", "Cytochrome c/quinol oxidase subunit II [IPR045187]", "Cytochrome c1 [IPR002326]", "Cytoplasmic FMR1-interacting [IPR008081]", "Cytoplasmic dynein 1 intermediate chain 1/2 [IPR025956]", "Cytoplasmic dynein 2 heavy chain 1 [IPR026815]", "Cytoplasmic protein NCK [IPR017304]", "Cytoplasmic protein NCK1 [IPR028526]", "Cytoplasmic protein NCK2 [IPR028524]", "Cytoskeleton-associated protein 2 family [IPR026165]", "Cytoskeleton-associated protein 4 [IPR028428]", "Cytosolic Fe-S cluster assembly factor NUBP2/Cfd1, eukaryotes [IPR028600]", "Cytosolic acyl coenzyme A thioester hydrolase [IPR040170]", "Cytosolic nonspecific dipeptidase/DUG1 [IPR017153]", "Cytospin-A [IPR040166]", "D-3-phosphoglycerate dehydrogenase [IPR006236]", "DAD/Ost2 [IPR003038]", "DDRGK domain containing protein [IPR019153]", "DDX54/DBP10 family [IPR033517]", "DENR family, eukaryotes [IPR005873]", "DET1- and DDB1-associated protein 1 [IPR033575]", "DNA (cytosine-5)-methyltransferase 1-like [IPR017198]", "DNA damage-binding protein 1 [IPR031297]", "DNA double-strand break repair protein Mre11 [IPR003701]", "DNA fragmentation factor 45 [IPR017299]", "DNA helicase, ATP-dependent, RecQ type [IPR004589]", "DNA ligase, ATP-dependent [IPR000977]", "DNA mismatch repair Msh2-type [IPR011184]", "DNA mismatch repair MutS family [IPR045076]", "DNA mismatch repair protein Msh2 [IPR032642]", "DNA mismatch repair protein MutL/Mlh/Pms [IPR038973]", "DNA mismatch repair protein MutS/MSH [IPR017261]", "DNA polymerase V/Myb-binding protein 1A [IPR007015]", "DNA polymerase alpha, subunit B [IPR016722]", "DNA polymerase delta/II small subunit family [IPR024826]", "DNA polymerase epsilon catalytic subunit [IPR029703]", "DNA primase large subunit, eukaryotic/archaeal [IPR007238]", "DNA primase, large subunit, eukaryotic [IPR016558]", "DNA primase, small subunit [IPR002755]", "DNA primase, small subunit, eukaryotic/archaeal [IPR014052]", "DNA repair protein Rad50, eukaryotes [IPR004584]", "DNA repair/transcription protein MET18/MMS19 [IPR039920]", "DNA replication licensing factor Mcm2 [IPR008045]", "DNA replication licensing factor Mcm3 [IPR008046]", "DNA replication licensing factor Mcm5 [IPR008048]", "DNA replication licensing factor Mcm6 [IPR008049]", "DNA replication licensing factor Mcm7 [IPR008050]", "DNA replication/checkpoint protein [IPR021110]", "DNA topoisomerase I [IPR001631]", "DNA topoisomerase II, eukaryotic-type [IPR001154]", "DNA topoisomerase II-beta [IPR028467]", "DNA topoisomerase, type IA [IPR000380]", "DNA topoisomerase, type IIA [IPR001241]", "DNA-binding protein SATB1/SATB2 [IPR039673]", "DNA-directed DNA polymerase, family B [IPR006172]", "DNA-directed RNA pol I, largest subunit [IPR015699]", "DNA-directed RNA polymerase I, subunit RPA34.5 [IPR013240]", "DNA-directed RNA polymerase II subunit Rpb4-like [IPR045222]", "DNA-directed RNA polymerase III subunit RPC3 [IPR039748]", "DNA-directed RNA polymerase subunit RPABC5/Rpb10 [IPR000268]", "DNA-directed RNA polymerase subunit Rpo5/Rpb5 [IPR014381]", "DNA-directed RNA polymerase, phage-type [IPR002092]", "DNA-directed RNA polymerase, subunit 2 [IPR015712]", "DNA-directed RNA polymerase, subunit beta-prime [IPR045867]", "DNA-directed RNA polymerases I and III subunit AC40 [IPR033901]", "DNA2/NAM7-like helicase [IPR045055]", "DPM1-like [IPR039528]", "DUF5568 family [IPR040419]", "Daxx protein [IPR005012]", "Death-inducer obliterator 1 [IPR033082]", "Dedicator of cytokinesis [IPR026791]", "Defective-in-cullin neddylation protein [IPR014764]", "Dehydrogenase/reductase SDR member 4-like [IPR029511]", "Delta l-pyrroline-5-carboxylate synthetase [IPR005766]", "Delta(24)-sterol reductase [IPR040165]", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase Ech1-like [IPR045002]", "Delta-1-pyrroline-5-carboxylate dehydrogenase [IPR005931]", "Deoxyhypusine hydroxylase [IPR027517]", "Deoxyhypusine synthase [IPR002773]", "Deoxyuridine triphosphate nucleotidohydrolase [IPR008181]", "Dephospho-CoA kinase [IPR001977]", "Derlin [IPR007599]", "Dermcidin [IPR028130]", "Dermcidin/Lacritin [IPR043557]", "Desmoglein [IPR009123]", "Desmoplakin [IPR028462]", "Desmosomal cadherin [IPR009122]", "Destrin [IPR029924]", "Deubiquitinating enzyme MINDY-3/4 [IPR039785]", "Developmentally regulated GTP-binding protein [IPR045001]", "Dihydrofolate reductase [IPR012259]", "Dihydrolipoamide acetyltransferase/Pyruvate dehydrogenase protein X component [IPR045257]", "Dihydrolipoamide dehydrogenase [IPR006258]", "Dihydrolipoamide succinyltransferase [IPR006255]", "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex [IPR006257]", "Dihydropyrimidinase-related protein 2 [IPR030615]", "Dihydropyrimidinase-related protein 3 [IPR030628]", "Dihydropyrimidinase-related protein 5 [IPR030626]", "Dihydroxyacetone phosphate acyltransferase [IPR028353]", "Dimethylallyltransferase [IPR039657]", "Dipeptidyl-peptidase 3 [IPR005317]", "Diphthamide synthesis DHP2 [IPR010014]", "Diphthamide synthesis DPH1/DPH2 [IPR016435]", "Diphthine synthase [IPR004551]", "Dishevelled family [IPR008339]", "Dishevelled-2 [IPR008341]", "Dishevelled-related protein [IPR015506]", "Disks large 1-like [IPR016313]", "Divalent ion tolerance protein, CutA [IPR004323]", "Divergent protein kinase domain 2A/B [IPR020519]", "DnaJ homolog subfamily A member 1/2-like [IPR044713]", "DnaJ homolog subfamily C member 8 [IPR042858]", "DnaJ homologue subfamily C member 10 [IPR021170]", "DnaJ homologue subfamily C, GRV2/DNAJC13 [IPR044978]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48kDa subunit [IPR005013]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit Swp1 [IPR008814]", "Dolichyldiphosphatase 1 [IPR039666]", "Drebrin [IPR028438]", "Drebrin-like protein [IPR029923]", "Dual specificity protein phosphatase 12 [IPR016278]", "Dymeclin [IPR019142]", "Dynactin subunit 3 [IPR009991]", "Dynactin subunit 4 [IPR008603]", "Dynamin [IPR022812]", "Dynamin-1-like protein [IPR030556]", "Dynamin-2 [IPR027188]", "Dynamin-like 120kDa protein, mitochondrial [IPR033047]", "Dynamitin [IPR028133]", "Dynein 1 light intermediate chain [IPR008467]", "Dynein family light intermediate chain [IPR022780]", "Dynein heavy chain [IPR026983]", "Dynein light chain, type 1/2 [IPR001372]", "Dynein regulator LIS1 [IPR017252]", "Dyslexia-associated protein KIAA0319-like [IPR029865]", "Dystrophin/utrophin [IPR035436]", "E3 SUMO-protein ligase Nse2 (Mms21) [IPR026846]", "E3 UFM1-protein ligase 1 [IPR018611]", "E3 ubiquitin ligase Bre1 [IPR013956]", "E3 ubiquitin ligase RBR family [IPR031127]", "E3 ubiquitin ligase UBR4-like [IPR045189]", "E3 ubiquitin-protein ligase CHIP/LubX [IPR045200]", "E3 ubiquitin-protein ligase HECTD1/TRIP12-like [IPR045322]", "E3 ubiquitin-protein ligase HECTD3 [IPR042469]", "E3 ubiquitin-protein ligase RBBP6 family [IPR033489]", "E3 ubiquitin-protein ligase RNF14 [IPR031128]", "E3 ubiquitin-protein ligase ZNF598/Hel2 [IPR044288]", "E3 ubiquitin-protein ligase listerin [IPR039795]", "E3 ubiquitin-protein ligase, SMURF1 type [IPR024928]", "EB1, Metazoa [IPR027739]", "EB2, vertebrate [IPR027735]", "ECSIT [IPR010418]", "EF-hand domain-containing protein D1/2 [IPR040365]", "EH domain-containing protein 1/3 [IPR029951]", "EH domain-containing protein 4 [IPR029952]", "ELL/occludin family [IPR031176]", "ELMO domain-containing protein 2 [IPR030724]", "ELP3/YhcC [IPR039661]", "ER lumen protein retaining receptor [IPR000133]", "ER membrane protein complex subunit 1 [IPR026895]", "ER membrane protein complex subunit 2-like [IPR039856]", "ER membrane protein complex subunit 3 [IPR008568]", "ER membrane protein complex subunit 7 [IPR039163]", "ERAP2 aminopeptidase [IPR033528]", "ERG2/sigma1 receptor-like [IPR006716]", "ERp19 [IPR037462]", "ESCRT-II complex, Vps25 subunit [IPR008570]", "Ecd family [IPR010770]", "Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 [IPR029890]", "Electron transfer flavoprotein alpha subunit/FixB [IPR001308]", "Electron transfer flavoprotein, beta subunit [IPR012255]", "Electron transfer flavoprotein-ubiquinone oxidoreductase [IPR040156]", "Elongation factor 4 [IPR006297]", "Elongation factor G1-like [IPR045044]", "Elongator complex protein 1 [IPR006849]", "Elongator complex protein 2 [IPR037289]", "Elongator complex protein 3-like [IPR034687]", "Elongin B [IPR039049]", "Elongin-C [IPR039948]", "Emerin [IPR035004]", "Emopamil-binding protein [IPR007905]", "Endonuclease III-like protein 1 [IPR030841]", "Endonuclease domain-containing 1 protein [IPR039015]", "Endophilin-A [IPR028501]", "Endophilin-B1 [IPR028503]", "Endoplasmic reticulum aninopeptidase 1 [IPR033520]", "Endoplasmic reticulum oxidoreductin 1 [IPR007266]", "Endoplasmic reticulum protein SC65 [IPR033213]", "Endoplasmic reticulum resident protein 29 [IPR016855]", "Endoplasmic reticulum vesicle transporter [IPR045888]", "Endosome-associated-trafficking regulator 1 [IPR026757]", "Endosulphine [IPR006760]", "Endothelin-converting enzyme 1 [IPR029734]", "Engulfment and cell motility protein 2 [IPR030713]", "Enhancer of mRNA-decapping protein 4-like [IPR045152]", "Enhancer of rudimentary [IPR000781]", "Enolase [IPR000941]", "Enoyl-CoA hydratase/isomerase [IPR001753]", "Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type [IPR032259]", "Ependymin [IPR001299]", "Ephrin receptor type-A /type-B [IPR016257]", "Epoxide hydrolase [IPR016292]", "Epoxide hydrolase-like [IPR000639]", "Equilibrative nucleoside transporter 1 [IPR030195]", "Equilibrative nucleoside transporter [IPR002259]", "Erbin [IPR032927]", "Ergosterol biosynthesis ERG4/ERG24 [IPR001171]", "Erlin1/2 [IPR033294]", "Esterase-like [IPR000801]", "Etoposide-induced 2.4 [IPR009890]", "Eukaryotic porin/Tom40 [IPR027246]", "Eukaryotic rRNA processing [IPR008610]", "Eukaryotic translation elongation factor 1 epsilon-1 [IPR042450]", "Eukaryotic translation initiation factor 2D [IPR039757]", "Eukaryotic translation initiation factor 3 subunit A [IPR027512]", "Eukaryotic translation initiation factor 3 subunit B [IPR011400]", "Eukaryotic translation initiation factor 3 subunit D [IPR007783]", "Eukaryotic translation initiation factor 3 subunit E [IPR016650]", "Eukaryotic translation initiation factor 3 subunit F [IPR027531]", "Eukaryotic translation initiation factor 3 subunit G [IPR017334]", "Eukaryotic translation initiation factor 3 subunit H [IPR027524]", "Eukaryotic translation initiation factor 3 subunit I [IPR027525]", "Eukaryotic translation initiation factor 3 subunit J [IPR013906]", "Eukaryotic translation initiation factor 3 subunit K [IPR009374]", "Eukaryotic translation initiation factor 3 subunit M [IPR027528]", "Eukaryotic translation initiation factor 3 subunit M eIF3m/COP9 signalosome complex subunit 7 COPS7 [IPR045237]", "Eukaryotic translation initiation factor 4 gamma 1 [IPR037584]", "Eukaryotic translation initiation factor 4 gamma 3 [IPR037585]", "Eukaryotic translation initiation factor 4B [IPR033107]", "Exocyst complex component EXOC2/Sec5 [IPR029175]", "Exocyst complex component EXOC3/Sec6 [IPR010326]", "Exocyst complex component EXOC5/Sec10 [IPR033960]", "Exocyst complex component EXOC6/Sec15 [IPR007225]", "Exocyst complex component Exo70 [IPR004140]", "Exocyst complex component Sec10-like [IPR009976]", "Exocyst complex component Sec8/EXOC4 [IPR039682]", "Exonuclease 1 [IPR032641]", "Exosome complex RNA-binding protein 1/RRP40/RRP4 [IPR026699]", "Exosome complex component Csl4 [IPR039771]", "Exosome complex component RRP45 [IPR033100]", "Exosome complex exonuclease Rrp6-like [IPR045092]", "Exosome-associated factor Rrp47/DNA strand repair C1D [IPR011082]", "Exportin 4/7-like [IPR044189]", "Exportin-1/5 [IPR045065]", "Exportin-5 [IPR040018]", "Exportin-7 [IPR040021]", "Exportin-T [IPR040017]", "Eyes absent family [IPR028472]", "Eyes absent homologue 4 [IPR028478]", "Ezrin/radixin/moesin [IPR011174]", "Ezrin/radixin/moesin-like [IPR000798]", "F-actin-capping protein subunit alpha [IPR002189]", "F-actin-capping protein subunit beta [IPR001698]", "FACT complex subunit Spt16 [IPR040258]", "FAD synthetase with the MoaB/Mog domain [IPR012183]", "FAD-dependent glycerol-3-phosphate dehydrogenase [IPR000447]", "FAD-dependent oxidoreductase SdhA/FrdA/AprA [IPR030664]", "FAM175 family [IPR023238]", "FAM175 family, BRISC complex, Abro1 subunit [IPR023240]", "FAM177 family [IPR028260]", "FAM3 family [IPR039220]", "FAM98 [IPR018797]", "FH1/FH2 domain-containing protein 1 [IPR027647]", "FUN14 [IPR007014]", "Fanconi anaemia protein FANCD2 [IPR029448]", "Fanconi anemia group I protein [IPR026171]", "Far11/STRP [IPR040185]", "Fascin [IPR010431]", "Fascin, metazoans [IPR024703]", "Fascin-1 [IPR030146]", "Fatty acid desaturase [IPR012171]", "Fatty acid oxidation complex, alpha subunit, mitochondrial [IPR012803]", "Fatty acid transport protein 2 [IPR030305]", "Fatty acid transport protein 4 [IPR030304]", "Fatty acyl-CoA reductase [IPR026055]", "Fcf2/DNTTIP2 [IPR039883]", "Ferredoxin-NADP+ reductase, adrenodoxin-type [IPR021163]", "Ferrochelatase [IPR001015]", "Fibrillarin [IPR000692]", "Filamin family [IPR044801]", "Filamin-B [IPR029874]", "Fimbrin/Plastin [IPR039959]", "Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 [IPR033756]", "Flap endonuclease 1 [IPR023426]", "Flotillin family [IPR027705]", "Formate-tetrahydrofolate ligase, FTHFS [IPR000559]", "Formin, protein diaphanous homologue 1 [IPR027653]", "Formin, protein diaphanous homologue 3 [IPR027654]", "Formin-binding protein 1-like [IPR030116]", "Four and a half LIM domains protein 1 [IPR042997]", "Fragile X mental retardation syndrome-related protein [IPR040148]", "Fructosamine/Ketosamine-3-kinase [IPR016477]", "Fructose-bisphosphate aldolase, class-I [IPR000741]", "Fumarate hydratase, class II [IPR005677]", "Fumarate lyase family [IPR000362]", "Fumarylacetoacetase [IPR005959]", "G-protein alpha subunit, group 12/13 [IPR000469]", "G-protein alpha subunit, group I [IPR001408]", "G-protein, gamma subunit [IPR001770]", "G-rich sequence factor 1 [IPR033106]", "G10 protein [IPR001748]", "GDP dissociation inhibitor [IPR018203]", "GDP-L-fucose synthase/GDP-L-colitose synthase [IPR028614]", "GDP-fucose protein O-fucosyltransferase 1 [IPR039922]", "GDP-fucose protein O-fucosyltransferase 2-like [IPR045130]", "GDP-fucose protein O-fucosyltransferase [IPR019378]", "GH3 family [IPR004993]", "GINS complex subunit Sld5 [IPR008591]", "GINS complex, subunit Psf3 [IPR010492]", "GPCR-associated sorting protein [IPR043374]", "GPI transamidase component Gaa1 [IPR007246]", "GPI transamidase component PIG-T [IPR007245]", "GPI-anchor transamidase [IPR028361]", "GRASP55/65 [IPR007583]", "GRIM-19 [IPR009346]", "GRIP1-associated protein 1 [IPR026204]", "GTP-binding protein 1 [IPR039263]", "GTP-binding protein Era [IPR005662]", "GTP-binding protein Obg/CgtA [IPR014100]", "GTP-binding protein Rheb [IPR037586]", "Galactokinase [IPR000705]", "Galectin-3 [IPR015534]", "Galectin-like [IPR044156]", "Gamma-adducin [IPR027772]", "Gamma-glutamylcyclotransferase [IPR017939]", "Gamma-tubulin complex component protein [IPR007259]", "Ganglioside GM2 activator [IPR028996]", "Ganglioside-induced differentiation-associated protein 1 [IPR034336]", "Gdt1 family [IPR001727]", "Gem-associated protein 4 [IPR033265]", "General transcription factor 3C polypeptide 4 [IPR044230]", "Geranylgeranyl transferase type-2 subunit alpha [IPR032955]", "Glia maturation factor [IPR011171]", "Glomulin/ALF4 [IPR019516]", "Glu-tRNAGln amidotransferase C subunit [IPR003837]", "Glucosamine-6-phosphate isomerase [IPR004547]", "Glucosamine-fructose-6-phosphate aminotransferase, isomerising [IPR005855]", "Glucose-6-phosphate dehydrogenase [IPR001282]", "Glucosidase II beta subunit-like [IPR039794]", "Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase [IPR005715]", "Glutamate carboxypeptidase 2-like [IPR039373]", "Glutamate-tRNA ligase, bacterial/mitochondrial [IPR004527]", "Glutamate/acetylglutamate kinase [IPR001057]", "Glutamate/phenylalanine/leucine/valine dehydrogenase [IPR006095]", "Glutaminase [IPR015868]", "Glutamine-tRNA synthetase [IPR004514]", "Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic [IPR004526]", "Glutamyl-tRNA(Gln) amidotransferase A subunit [IPR004412]", "Glutamyl/glutaminyl-tRNA synthetase [IPR000924]", "Glutathione S-transferase Omega/Tau-like [IPR045073]", "Glutathione S-transferase kappa [IPR044088]", "Glutathione S-transferase, Mu class [IPR003081]", "Glutathione S-transferase, omega-class [IPR005442]", "Glutathione S-transferases, class Zeta [IPR005955]", "Glutathione Transferase family [IPR040079]", "Glutathione reductase, eukaryote/bacterial [IPR006322]", "Glutathione synthase [IPR005615]", "Glutathione-specific gamma-glutamylcyclotransferase [IPR006840]", "Glyceraldehyde-3-phosphate dehydrogenase, type I [IPR006424]", "Glyceraldehyde/Erythrose phosphate dehydrogenase family [IPR020831]", "Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase [IPR022284]", "Glycerol-3-phosphate acyltransferase, PlsB [IPR028354]", "Glycine cleavage system P protein [IPR020581]", "Glycine dehydrogenase (decarboxylating) [IPR003437]", "Glycogen debranching enzyme [IPR010401]", "Glycogen debranching enzyme, metazoa [IPR006421]", "Glycogen synthase [IPR008631]", "Glycogen synthase kinase-3 beta [IPR033573]", "Glycogen/starch/alpha-glucan phosphorylase [IPR011833]", "Glycoside hydrolase family 30 [IPR001139]", "Glycoside hydrolase family 31 [IPR000322]", "Glycoside hydrolase family 47 [IPR001382]", "Glycoside hydrolase family 63 [IPR004888]", "Glycoside hydrolase, family 2 [IPR006101]", "Glycoside hydrolase, family 27 [IPR002241]", "Glycoside hydrolase, family 29 [IPR000933]", "Glycoside hydrolase, family 35 [IPR001944]", "Glycoside hydrolase, family 79 [IPR005199]", "Glycosyl transferase, family 25 [IPR002654]", "Glycosyl transferase, family 35 [IPR000811]", "Glycosyl transferase, family 8 [IPR002495]", "Glycosyltransferase 61 [IPR007657]", "Glycyl-tRNA synthetase [IPR002315]", "Glycyl-tRNA synthetase/DNA polymerase subunit gamma-2 [IPR027031]", "Glyoxalase I [IPR004361]", "Glyoxalase domain-containing protein 4 [IPR043193]", "Golgi SNAP receptor complex, subunit 1 [IPR023601]", "Golgi apparatus protein 1 [IPR039728]", "Golgi integral membrane protein 4 [IPR042336]", "Golgi phosphoprotein 3-like [IPR008628]", "Golgi to ER traffic protein 4 [IPR007317]", "Golgi-associated PDZ and coiled-coil motif-containing protein [IPR038879]", "Golgin subfamily A [IPR024858]", "Golgin subfamily A member 3 [IPR033288]", "Golgin subfamily A member 5 [IPR019177]", "Golgin subfamily B member 1 [IPR026202]", "Graves disease carrier protein [IPR002167]", "GroES chaperonin family [IPR020818]", "Growth arrest/ DNA-damage-inducible protein-interacting protein 1 [IPR018472]", "GrpE nucleotide exchange factor [IPR000740]", "Guanine nucleotide binding protein (G-protein), alpha subunit [IPR001019]", "Guanine nucleotide exchange factor, Ric8 [IPR019318]", "Guanine nucleotide-exchange factor Sec12-like [IPR045260]", "Guided entry of tail-anchored proteins factor CAMLG [IPR016719]", "H/ACA ribonucleoprotein complex, subunit Gar1/Naf1 [IPR007504]", "H/ACA ribonucleoprotein complex, subunit Nhp2, eukaryote [IPR002415]", "HAD hydrolase, LHPP/HDHD2 [IPR006355]", "HAD hydrolase, subfamily IA [IPR006439]", "HAD-superfamily hydrolase, subfamily IA, REG-2-like [IPR011949]", "HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase [IPR008380]", "HAD-superfamily hydrolase, subfamily IIA [IPR006357]", "HAD-superfamily hydrolase, subfamily IIA, CECR5 [IPR006353]", "HAUS augmin-like complex subunit 1 [IPR026243]", "HAUS augmin-like complex subunit 4 [IPR029327]", "HAUS augmin-like complex subunit 4, metazoa [IPR026214]", "HAUS augmin-like complex subunit 5 [IPR029131]", "HAUS augmin-like complex subunit 6 [IPR026797]", "HAUS complex subunit 5, metazoa [IPR026215]", "HCCA isomerase/glutathione S-transferase kappa [IPR014440]", "HEXIM [IPR024872]", "HIRA-interacting protein 3 [IPR037647]", "HMG domain-containing protein 4 [IPR042477]", "HMG-CoA lyase [IPR043594]", "HS1-associating protein X-1 [IPR017248]", "Haem oxygenase [IPR002051]", "Haem oxygenase-like [IPR016053]", "Haloacid dehalogenase-like hydrolase [IPR041492]", "Ham1-like protein [IPR002637]", "Heat shock 70kDa protein 13 [IPR042048]", "Heat shock protein 70 family [IPR013126]", "Heat shock protein Hsp90 family [IPR001404]", "Heat shock protein Sti1-like [IPR045248]", "Helicase MOV-10 [IPR026122]", "Helicase SMUBP-2/Hcs1-like [IPR004483]", "Helicase XPB/Ssl2 [IPR001161]", "Helicase superfamily 1/2, DinG/Rad3-like [IPR045028]", "Heparan sulphate 2-O-sulfotransferase [IPR007734]", "Hermansky-Pudlak syndrome 3 protein [IPR017216]", "Heterochromatin protein 1-binding protein 3 [IPR033061]", "Heterogeneous nuclear ribonucleoprotein C [IPR017347]", "Heterogeneous nuclear ribonucleoprotein K [IPR033090]", "Heterogeneous nuclear ribonucleoprotein M [IPR024667]", "Heterogeneous nuclear ribonucleoprotein U [IPR026745]", "Heterogeneous nuclear ribonucleoprotein U-like protein 1 [IPR027025]", "Hexokinase [IPR001312]", "High mobility group protein HMG-I/HMG-Y, chordates [IPR031079]", "High mobility group protein HMGA [IPR000116]", "High mobility group protein HMGB1 [IPR031076]", "High mobility group protein HMGB3 [IPR031077]", "High mobility group protein HMGN [IPR000079]", "High mobility group protein HMGN3 [IPR031073]", "Higher eukaryotic phosphomevalonate kinase [IPR005919]", "Histidine acid phosphatase, eukaryotic [IPR016274]", "Histidine phosphatase superfamily, clade-1 [IPR013078]", "Histidine phosphatase superfamily, clade-2 [IPR000560]", "Histidine triad (HIT) protein [IPR001310]", "Histone H2A [IPR002119]", "Histone H4 [IPR001951]", "Histone acetyltransferase type B, catalytic subunit [IPR017380]", "Histone deacetylase [IPR003084]", "Histone deacetylase complex subunit SAP130 [IPR024137]", "Histone deacetylase complex, SAP18 subunit [IPR017250]", "Histone deacetylase family [IPR000286]", "Histone demethylase JHDM2-like [IPR045109]", "Histone lysine-specific demethylase [IPR017366]", "Histone-lysine N-methyltransferase 2A [IPR037927]", "Histone-lysine N-methyltransferase EHMT1/EHMT2 [IPR043550]", "Histone-lysine N-methyltransferase EHMT2 [IPR038034]", "Histone-lysine N-methyltransferase EZH1/2-like [IPR045318]", "Histone-lysine N-methyltransferase EZH1/EZH2 [IPR021654]", "Histone-lysine N-methyltransferase SETD1A [IPR037841]", "Histone-lysine N-methyltransferase SETDB1 [IPR025796]", "Histone-lysine N-methyltransferase Set1-like [IPR044570]", "Histone-lysine N-methyltransferase, SET [IPR017155]", "HnRNP R/Q splicing factor [IPR006535]", "HnRNP-L/PTB [IPR006536]", "Holocytochrome c/c1 synthase [IPR000511]", "Host cell factor 1 [IPR037854]", "Host cell factor [IPR043536]", "Huntingtin [IPR000091]", "Huntingtin family [IPR028426]", "Hydantoinase/dihydropyrimidinase [IPR011778]", "Hydroxymethylglutaryl-CoA synthase, eukaryotic [IPR010122]", "Hypoxanthine phosphoribosyl transferase [IPR005904]", "I-BAR domain containing protein IRSp53 [IPR030128]", "I-BAR domain containing protein IRSp53/IRTKS/Pinkbar [IPR027681]", "ICln [IPR003521]", "IPP transferase [IPR018022]", "ISC system FeS cluster assembly, IscU scaffold [IPR011339]", "Importin beta family [IPR040122]", "Importin subunit alpha [IPR024931]", "Inhibitor of nuclear factor kappa-B kinase-interacting protein [IPR024152]", "Initiation factor 2B-related [IPR000649]", "Initiation factor 4G [IPR045208]", "Inner centromere protein [IPR039130]", "Inner nuclear membrane protein Man1 [IPR034997]", "Inorganic pyrophosphatase [IPR008162]", "Inosine triphosphate pyrophosphatase [IPR027502]", "Inosine-5'-monophosphate dehydrogenase [IPR005990]", "Inositol 1,4,5-trisphosphate receptor-interacting protein [IPR024797]", "Inositol 1,4,5-trisphosphate receptor-interacting protein family [IPR026250]", "Inositol monophosphatase-like [IPR000760]", "Insulin receptor substrate [IPR039011]", "Insulin-like growth factor 2 mRNA-binding protein 2 [IPR028743]", "Integral membrane protein 2 [IPR040145]", "Integral membrane protein EMC3/TMCO1-like [IPR002809]", "Integrator complex subunit 1 [IPR038902]", "Integrator complex subunit 12 [IPR039053]", "Integrator complex subunit 14 [IPR039841]", "Integrator complex subunit 3 [IPR045334]", "Integrator complex subunit 7 [IPR033060]", "Integrator complex subunit 9 [IPR027074]", "Integrin beta subunit [IPR015812]", "Integrin beta-1 subunit [IPR027071]", "Interferon-induced protein with tetratricopeptide repeat 5 [IPR024125]", "Interferon-inducible double-stranded RNA-dependent protein kinase activator A [IPR033363]", "Interleukin enhancer-binding factor 3 [IPR033099]", "Intermembrane space protein MIX23 [IPR019171]", "Intracellular chloride channel [IPR002946]", "Intracellular hyaluronic acid binding protein [IPR026203]", "Intracellular lipid binding protein [IPR031259]", "Intraflagellar transport protein 27 homologue, eukaryotes [IPR034112]", "Intraflagellar transport protein 52 homolog [IPR039975]", "Intron Large complex component GCFC2-like [IPR012890]", "Inverted formin-2 [IPR027649]", "Iron regulatory protein 1 [IPR029784]", "Iron-sulfur protein NUBPL-like [IPR044304]", "Isocitrate dehydrogenase NAD-dependent [IPR004434]", "Isocitrate dehydrogenase NADP-dependent [IPR004790]", "Isoleucine-tRNA ligase [IPR002301]", "Isoleucine-tRNA ligase, type 1 [IPR023585]", "Isoleucine-tRNA ligase, type 2 [IPR023586]", "Isopentenyl-diphosphate delta-isomerase, type 1 [IPR011876]", "Isoprenylcysteine carboxyl methyltransferase [IPR007269]", "Isovaleryl-CoA dehydrogenase [IPR034183]", "J-protein Zuotin/DnaJC2 [IPR044634]", "JNK-interacting protein 3/4 [IPR039911]", "JmjC domain-containing [IPR039994]", "Junction plakoglobin [IPR030461]", "Junctional adhesion molecule A [IPR042456]", "KH domain-containing BBP-like [IPR045071]", "KIF-1 binding protein [IPR022083]", "KIN17-like protein [IPR037321]", "KRR1 interacting protein 1 [IPR018034]", "Kae1/TsaD family [IPR017861]", "Kelch-like ECH-associated protein 1 [IPR030563]", "Keratin, type I [IPR002957]", "Keratinocyte-associated transmembrane protein 2 [IPR037645]", "Kindlin/fermitin [IPR037843]", "Kinectin [IPR024854]", "Kinesin light chain [IPR002151]", "Kinesin-like protein KIF20A [IPR027326]", "Kinesin-like protein KIF20B [IPR028828]", "Kinesin-like protein KIF22 (Kid) [IPR026986]", "Kinesin-like protein [IPR027640]", "Kinetochore protein Spc25 [IPR045143]", "Kinetochore-Ndc80 subunit Spc24 [IPR013252]", "Ku70 [IPR006165]", "Ku80 [IPR024193]", "Kynurenine--oxoglutarate transaminase 3 [IPR034612]", "L-lactate dehydrogenase [IPR011304]", "L-lactate/malate dehydrogenase [IPR001557]", "LAMTOR1/MEH1 [IPR028209]", "LEM domain-containing protein 2 [IPR034994]", "LETM1/MDM38-like [IPR044202]", "LIM domain and actin-binding protein 1 [IPR028740]", "LIM domain and actin-binding protein LIMA-like [IPR045268]", "LRP chaperone MESD [IPR019330]", "La domain containing protein [IPR045180]", "LanC-like protein, eukaryotic [IPR020464]", "Lanthionine synthetase C-like [IPR007822]", "Las1 [IPR007174]", "Lecithin:cholesterol/phospholipid:diacylglycerol acyltransferase [IPR003386]", "Lethal(2) giant larvae protein [IPR000664]", "Leucine zipper protein 1 [IPR026734]", "Leucine zipper putative tumor suppressor [IPR045329]", "Leucine zipper putative tumour suppressor 2 [IPR028597]", "Leucine zipper transcription factor-like protein 1 [IPR026157]", "Leucine-rich PPR motif-containing protein [IPR033490]", "Leucine-rich repeat flightless-interacting protein 1/2 [IPR019139]", "Leucine-rich repeat protein SHOC2 [IPR027036]", "Leucine-tRNA ligase [IPR002302]", "Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic [IPR004493]", "Leukocyte surface antigen CD47 [IPR006704]", "Leukotriene A4 hydrolase/leucine aminopeptidase [IPR012777]", "Leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase [IPR014190]", "LicD family [IPR007074]", "Like-Sm (LSM) domain containing protein, LSm4/SmD1/SmD3 [IPR027141]", "Linker histone H1/H5 [IPR005819]", "Lipase maturation factor [IPR009613]", "Lipase, eukaryotic [IPR025483]", "Lipid droplet-associated hydrolase [IPR019363]", "Lon protease [IPR027065]", "Lon protease homologue 2, peroxisomal [IPR027501]", "Lon protease homologue, chloroplastic/mitochondrial [IPR027503]", "Lon protease, bacterial/eukaryotic-type [IPR004815]", "Long-chain fatty acid CoA synthetase, eukaryotic [IPR045311]", "Low temperature viability protein Ltv1 [IPR007307]", "Luc7-related [IPR004882]", "Lupus La protein [IPR002344]", "Lysine-tRNA ligase, class II [IPR002313]", "Lysophosphatidylserine lipase ABHD12 [IPR026605]", "Lysosomal thioesterase PPT2 [IPR030295]", "Lysosome membrane protein II [IPR005429]", "Lysosome-associated membrane glycoprotein [IPR002000]", "MCT-1/Tma20 [IPR016437]", "MCU family [IPR039055]", "MDN2-binding protein [IPR039061]", "MICOS complex subunit MIC19/MIC25 [IPR007964]", "MICOS complex subunit MIC26/MIC27 [IPR019166]", "MICOS complex subunit MIC26/MIC27, animal [IPR033182]", "MICOS complex subunit Mic13 [IPR026769]", "MIOS/Sea4 [IPR037593]", "MKRN-like [IPR045072]", "MOB kinase activator family [IPR005301]", "MRG [IPR008676]", "MRPS27/PTCD2 [IPR034913]", "Macrophage migration inhibitory factor [IPR001398]", "Mad2-like [IPR045091]", "Magnesium transporter protein 1 [IPR006844]", "Major centromere autoantigen B [IPR033062]", "Major facilitator superfamily [IPR011701]", "Major facilitator, sugar transporter-like [IPR005828]", "Mak16 protein [IPR006958]", "Malate dehydrogenase, NAD-dependent, cytosolic [IPR011274]", "Malate dehydrogenase, type 1 [IPR010097]", "Malate dehydrogenase, type 2 [IPR010945]", "Malectin [IPR039155]", "Malic oxidoreductase [IPR001891]", "Manganese/iron superoxide dismutase [IPR001189]", "Mannose-6-phosphate isomerase [IPR016305]", "Mannose-6-phosphate isomerase, type I [IPR001250]", "Mannosyltransferase ALG2 [IPR027054]", "Matrix-remodeling-associated protein 7 [IPR026622]", "Med25/PTOV1 [IPR045105]", "Mediator complex, subunit Med14 [IPR013947]", "Mediator complex, subunit Med16 [IPR021665]", "Mediator complex, subunit Med17 [IPR019313]", "Mediator complex, subunit Med21 [IPR021384]", "Mediator complex, subunit Med23 [IPR021629]", "Mediator complex, subunit Med24, [IPR021429]", "Mediator complex, subunit Med4 [IPR019258]", "Medium-chain dehydrogenase/reductase [IPR045010]", "Medium-chain specific acyl-CoA dehydrogenase [IPR034180]", "Melanoma-associated antigen D1 [IPR030083]", "Melanoma-associated antigen D2 [IPR028810]", "Melanoma-associated antigen [IPR037445]", "Membrane insertase YidC/ALB3/OXA1/COX18 [IPR001708]", "Membrane bound O-acyl transferase, MBOAT [IPR004299]", "Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein [IPR001129]", "Menin [IPR007747]", "Mesoderm induction early response protein/metastasis-associated protein [IPR040138]", "Metal-dependent protein hydrolase [IPR003226]", "Metastasis-associated protein MTA2 [IPR037964]", "Methionine-tRNA ligase, type 1 [IPR023458]", "Methionyl-tRNA synthetase [IPR014758]", "Methyl-CpG binding protein MeCP2 [IPR017353]", "Methyl-CpG binding protein MeCP2/MBD4 [IPR045138]", "Methyl-CpG-binding domain protein 3 [IPR037965]", "Methylcrotonoyl-CoA carboxylase beta chain MCCB/AccD1-like [IPR045190]", "Methylmalonate-semialdehyde dehydrogenase [IPR010061]", "Methylpurine-DNA glycosylase [IPR003180]", "Methylthioadenosine phosphorylase (MTAP) [IPR010044]", "Methylthiotransferase [IPR005839]", "Methyltransferase, trithorax [IPR016569]", "Mevalonate/galactokinase [IPR006206]", "Mff/Tango-11 [IPR008518]", "MiaB-like tRNA modifying enzyme, archaeal-type [IPR006466]", "Microfibrillar-associated protein 1 [IPR033194]", "Microprocessor complex subunit DGCR8 [IPR040375]", "Microsomal glutathione S-transferase 1-like [IPR040162]", "Microtubule associated protein 1 [IPR026074]", "Microtubule associated protein 1A [IPR015656]", "Microtubule-associated protein 1B [IPR027321]", "Microtubule-associated protein 1S [IPR027322]", "Microtubule-associated protein 4 [IPR027323]", "Microtubule-associated protein 7 family [IPR008604]", "Microtubule-associated protein Jupiter [IPR033335]", "Microtubule-associated protein RP/EB [IPR027328]", "Microtubule-associated protein, MAP65/Ase1/PRC1 [IPR007145]", "Midasin [IPR012099]", "Mini-chromosome maintenance complex protein 4 [IPR008047]", "Mini-chromosome maintenance complex-binding protein [IPR019140]", "Mini-chromosome maintenance protein [IPR031327]", "Minichromosome maintenance protein 10 [IPR040184]", "Mitochondrial 18kDa protein [IPR019560]", "Mitochondrial 28S ribosomal protein S31 [IPR026299]", "Mitochondrial 28S ribosomal protein S34 [IPR032053]", "Mitochondrial ATP synthase subunit g, animal [IPR016702]", "Mitochondrial ATPase inhibitor [IPR007648]", "Mitochondrial F1-F0 ATP synthase subunit F, predicted [IPR019344]", "Mitochondrial Rho GTPase 1 [IPR029506]", "Mitochondrial Rho GTPase [IPR021181]", "Mitochondrial antiviral-signalling protein, metazoan [IPR026148]", "Mitochondrial carrier UCP-like [IPR002030]", "Mitochondrial carrier protein Mtm1-like [IPR045315]", "Mitochondrial carrier protein [IPR002067]", "Mitochondrial glycoprotein [IPR003428]", "Mitochondrial import inner membrane translocase subunit Tim44 [IPR017303]", "Mitochondrial import inner membrane translocase subunit Tim50 [IPR027111]", "Mitochondrial import inner membrane translocase subunit Tim8/13 [IPR039238]", "Mitochondrial import receptor subunit TOM5, metazoa [IPR029179]", "Mitochondrial import receptor subunit Tom22 [IPR005683]", "Mitochondrial inner membrane protein Mitofilin [IPR019133]", "Mitochondrial inner membrane translocase complex, subunit Tim17 [IPR005678]", "Mitochondrial inner membrane translocase complex, subunit Tim23 [IPR005681]", "Mitochondrial outer membrane translocase complex, subunit Tom5 [IPR019603]", "Mitochondrial outer membrane transport complex protein, metaxin [IPR017410]", "Mitochondrial phosphate carrier protein Pic2/Mir1-like [IPR044677]", "Mitochondrial processing peptidase subunit beta [IPR037718]", "Mitochondrial pyruvate carrier [IPR005336]", "Mitochondrial ribonuclease P catalytic subunit [IPR033495]", "Mitochondrial ribosomal protein L48 [IPR027487]", "Mitochondrial-processing peptidase subunit alpha [IPR037715]", "Mitofusin family [IPR027094]", "Mitofusin-1 [IPR027088]", "Mitogen-activated protein (MAP) kinase p38-like [IPR008352]", "Mitogen-activated protein (MAP) kinase, ERK1/2 [IPR008349]", "Mitogen-activated protein kinase 14 [IPR038784]", "Mitotic spindle checkpoint protein Bub1/Mad3 [IPR015661]", "Mo25-like [IPR013878]", "Molecular chaperone regulator BAG [IPR039773]", "Molybdate-anion transporter [IPR008509]", "Molybdate-anion transporter, animal type [IPR030163]", "Molybdopterin biosynthesis protein MoeA-like [IPR038987]", "Monocarboxylate transporter 1 [IPR030757]", "Monocarboxylate transporter [IPR004743]", "Monothiol glutaredoxin-related [IPR004480]", "Mortality factor 4-like protein 1 [IPR038011]", "Mortality factor 4-like protein 2 [IPR038012]", "Mpv17/PMP22 [IPR007248]", "Mrp/NBP35 ATP-binding protein [IPR019591]", "Multi drug resistance-associated protein [IPR005292]", "Multidrug resistance protein 1 [IPR030258]", "Multifunctional methyltransferase subunit Trm112 [IPR039127]", "Multiple PDZ domain protein [IPR032078]", "Multiple myeloma tumor-associated protein 2-like [IPR039207]", "Myelin expression factor 2 [IPR034632]", "Myeloid-derived growth factor [IPR018887]", "Myo-inositol-1-phosphate synthase [IPR002587]", "Myotubularin [IPR030561]", "Myotubularin family [IPR030564]", "Myotubularin-related protein 6 [IPR030581]", "Myristoyl-CoA:protein N-myristoyltransferase [IPR000903]", "Myristoylated alanine-rich C-kinase substrate MARCKS [IPR002101]", "N-acetylglucosamine-6-sulfatase [IPR012251]", "N-acetylglucosamine-6-sulfatase, metazoan [IPR015981]", "N-acetylglucosaminyl phosphatidylinositol deacetylase-related [IPR003737]", "N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase [IPR039516]", "N-acetyltransferase Ard1-like [IPR045047]", "N-alpha-acetyltransferase 40 [IPR039949]", "N-cadherin [IPR030051]", "N-terminal acetyltransferase A, auxiliary subunit [IPR021183]", "NAD kinase 2, mitochondrial [IPR012355]", "NAD kinase [IPR002504]", "NAD(P) transhydrogenase, alpha subunit [IPR026255]", "NAD(P)H-quinone oxidoreductase subunit D/H [IPR022885]", "NAD/FAD transporter SLC25A32-like [IPR044712]", "NADH dehydrogenase, subunit C [IPR010218]", "NADH ubiquinone oxidoreductase, F subunit [IPR011537]", "NADH-quinone oxidoreductase subunit E-like [IPR002023]", "NADH-ubiquinone oxidoreductase, 20 Kd subunit [IPR006138]", "NADH-ubiquinone oxidoreductase, subunit 10 [IPR019377]", "NADH-ubiquinone reductase complex 1 MLRQ subunit [IPR010530]", "NADH:cytochrome b5 reductase-like [IPR001834]", "NADH:ubiquinone oxidoreductase, ESSS subunit [IPR019329]", "NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit [IPR019173]", "NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H [IPR001694]", "NADH:ubiquinone oxidoreductase, subunit G [IPR010228]", "NADH:ubiquinone oxidoreductase, subunit NDUFB4 [IPR009866]", "NADPH-cytochrome P450 reductase [IPR023208]", "NDRG [IPR004142]", "NDUFAF3/Mth938 domain-containing protein [IPR007523]", "NEDD8 ultimate buster 1 [IPR039749]", "NEDD8-activating enzyme E1 regulatory subunit APP-BP1 [IPR030667]", "NF-kappa-B/Dorsal [IPR000451]", "NOL6/Upt22 [IPR005554]", "NPC1-like [IPR004765]", "NSF attachment protein [IPR000744]", "Nck-associated protein 1 [IPR019137]", "Nectin-2 [IPR033318]", "Negative elongation factor E [IPR033102]", "Nesprin-2 [IPR030266]", "Nestin [IPR031211]", "Neurabin-2 [IPR029921]", "Neurabin-like family [IPR043446]", "Neural cell adhesion [IPR009138]", "Neural cell adhesion molecule 1 [IPR033019]", "Neurochondrin [IPR008709]", "Neurofilament light polypeptide [IPR027692]", "Neurofilament medium polypeptide [IPR027697]", "Neuropilin [IPR014648]", "Neuropilin-1 [IPR027146]", "Neutral amino acid SLC6 transporter [IPR002438]", "Niban-like [IPR026088]", "Nibrin [IPR016592]", "Nibrin-related [IPR040227]", "Nicalin [IPR016574]", "Nicastrin [IPR008710]", "Nicotinamide phosphoribosyl transferase [IPR016471]", "Nitric oxide synthase-interacting protein [IPR016818]", "Non-specific endonuclease [IPR040255]", "Nonaspanin (TM9SF) [IPR004240]", "Nonsense-mediated mRNA decay protein 3 [IPR039722]", "Nonsense-mediated mRNA decay protein Nmd2/UPF2 [IPR039762]", "Not2/Not3/Not5 [IPR040168]", "Nuclear RNA export factor [IPR030217]", "Nuclear cap-binding protein subunit 1 [IPR027159]", "Nuclear cap-binding protein subunit 3 [IPR019416]", "Nuclear factor hnRNPA1 [IPR021662]", "Nuclear factor related to kappa-B-binding protein [IPR024867]", "Nuclear fragile X mental retardation-interacting protein 2 [IPR032747]", "Nuclear hormone receptor [IPR001723]", "Nuclear mitotic apparatus protein 1 [IPR026650]", "Nuclear polyadenylated RNA-binding protein Nab2/ZC3H14 [IPR040366]", "Nuclear pore complex protein NUP98-NUP96 [IPR037637]", "Nuclear pore complex protein Nup133-like [IPR037624]", "Nuclear pore complex protein [IPR026054]", "Nuclear pore glycoprotein p62, metazoa [IPR033072]", "Nuclear pore membrane glycoprotein 210-like [IPR045197]", "Nuclear pore protein 84/107 [IPR007252]", "Nuclear protein DGCR14/ESS-2 [IPR019148]", "Nuclear protein localization protein 4 [IPR016563]", "Nuclear transport factor 2/Mtr2 [IPR045875]", "Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 [IPR026633]", "Nucleobindin [IPR040250]", "Nucleobindin-1 [IPR040253]", "Nucleobindin-2 [IPR028813]", "Nucleolar GTP-binding protein 1 [IPR024926]", "Nucleolar GTP-binding protein 2 [IPR024929]", "Nucleolar complex protein 2 [IPR005343]", "Nucleolar complex protein 4 [IPR027193]", "Nucleolar complex-associated protein 3 [IPR016903]", "Nucleolar pre-ribosomal-associated protein 1 [IPR039844]", "Nucleolar protein 10/Enp2 [IPR040382]", "Nucleolar protein 11 [IPR042859]", "Nucleolar protein 14 [IPR007276]", "Nucleolar protein 7 [IPR039626]", "Nucleolar protein 9 [IPR040000]", "Nucleolar protein Nop56/Nop58 [IPR045056]", "Nucleolar, Nop52 [IPR010301]", "Nucleoplasmin family [IPR004301]", "Nucleoporin NSP1/NUP62 [IPR026010]", "Nucleoporin NUP88/NUP82 [IPR037700]", "Nucleoporin Nup120/160 [IPR021717]", "Nucleoporin Nup186/Nup192/Nup205 [IPR021827]", "Nucleoporin Nup188 [IPR044840]", "Nucleoporin Nup37 [IPR037626]", "Nucleoporin Nup54/Nup57/Nup44 [IPR024864]", "Nucleoporin Nup85-like [IPR011502]", "Nucleoporin Nup88 [IPR019321]", "Nucleoporin Seh1 [IPR037597]", "Nucleoporin interacting component Nup93/Nic96 [IPR007231]", "Nucleoporin p58/p45 [IPR024882]", "Nucleoporin peptidase S59-like [IPR037665]", "Nucleoporin protein Ndc1-Nup [IPR019049]", "Nucleoporin, NUP53 [IPR017389]", "Nucleoporin, Nup155-like [IPR004870]", "Nucleoside 2-deoxyribosyltransferase [IPR007710]", "Nucleoside diphosphate kinase 7 [IPR011410]", "Nucleoside diphosphate kinase [IPR001564]", "Nucleoside transporter ENT1/ENT2 [IPR034764]", "Nucleoside-triphosphatase, THEP1 type [IPR004948]", "Nucleosome assembly protein (NAP) [IPR002164]", "Nucleosome-remodeling factor subunit BPTF [IPR038028]", "NudC domain-containing protein 1 [IPR037895]", "NudC family [IPR037898]", "OBG-type GTPase [IPR045086]", "OCIA domain-containing protein 1/2 [IPR040187]", "ODR-4-like [IPR029454]", "ORC ubiquitin ligase 1 [IPR039209]", "Occludin [IPR002958]", "Oligoribonuclease [IPR022894]", "Oligosaccharyl transferase complex, subunit OST3/OST6 [IPR021149]", "Oligosaccharyl transferase, STT3 subunit [IPR003674]", "Optic atrophy 3-like [IPR010754]", "Origin recognition complex, subunit 2 [IPR007220]", "Origin recognition complex, subunit 3 [IPR020795]", "Origin recognition complex, subunit 5 [IPR020796]", "Ornithine aminotransferase [IPR010164]", "Orotate phosphoribosyltransferase [IPR023031]", "Orotidine 5'-phosphate decarboxylase [IPR014732]", "Oxidized purine nucleoside triphosphate [IPR003563]", "Oxysterol-binding protein [IPR000648]", "P-type ATPase [IPR001757]", "P-type ATPase subfamily IIC, subunit alpha [IPR005775]", "P-type ATPase, subfamily IIA, SERCA-type [IPR005782]", "P-type ATPase, subfamily V [IPR006544]", "P-type ATPase, subfamily IIA, PMR1-type [IPR006413]", "P-type ATPase, subfamily IIB [IPR006408]", "P-type ATPase, subfamily IV [IPR006539]", "PA2G4 family [IPR004545]", "PAT complex subunit CCDC47 [IPR012879]", "PDCD5-like [IPR002836]", "PDK/BCKDK protein kinase [IPR039028]", "PDZ and LIM domain protein 1 [IPR028537]", "PEST proteolytic signal-containing nuclear protein [IPR029169]", "PEX5/PEX5L [IPR024111]", "PH-interacting protein [IPR028738]", "PHD finger protein 10 [IPR038045]", "PHF5-like [IPR005345]", "PITH domain-containing protein 1-like [IPR045099]", "PP2B [IPR043360]", "Pachytene checkpoint protein 2-like [IPR044539]", "Palmitoyl protein thioesterase [IPR002472]", "Palmitoyl-protein thioesterase 1 [IPR030294]", "Pantothenate kinase, acetyl-CoA regulated, two-domain type [IPR015844]", "Paraneoplastic antigen Ma [IPR026523]", "Paraneoplastic encephalomyelitis antigen [IPR002343]", "Paraoxonase2 [IPR008364]", "Partner of Y14 and mago [IPR039333]", "Pentatricopeptide repeat domain-containing protein 3 [IPR037387]", "Peptidase A22B, signal peptide peptidase [IPR007369]", "Peptidase C13, legumain [IPR001096]", "Peptidase C1B, bleomycin hydrolase [IPR004134]", "Peptidase C2, calpain family [IPR022684]", "Peptidase C26 [IPR011697]", "Peptidase C26, gamma-glutamyl hydrolase [IPR015527]", "Peptidase C50, separase [IPR005314]", "Peptidase C54 [IPR005078]", "Peptidase C65, otubain [IPR019400]", "Peptidase C69, dipeptidase A [IPR005322]", "Peptidase C78, ubiquitin fold modifier-specific peptidase 1/ 2 [IPR012462]", "Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930]", "Peptidase M1, aminopeptidase B [IPR015571]", "Peptidase M13 [IPR000718]", "Peptidase M14B, caboxypeptidase D [IPR015567]", "Peptidase M17, leucine aminopeptidase [IPR023042]", "Peptidase M17, leucine aminopeptidase/peptidase B [IPR011356]", "Peptidase M20 [IPR002933]", "Peptidase M24, methionine aminopeptidase [IPR001714]", "Peptidase M24A, methionine aminopeptidase, subfamily 1 [IPR002467]", "Peptidase M28 family [IPR045175]", "Peptidase M3A/M3B [IPR045090]", "Peptidase S10, serine carboxypeptidase [IPR001563]", "Peptidase S1C [IPR001940]", "Peptidase S26B [IPR001733]", "Peptidase S28 [IPR008758]", "Peptidase S8, subtilisin-related [IPR015500]", "Peptidase S9A, prolyl oligopeptidase [IPR002470]", "Peptidase T1A, proteasome beta-subunit [IPR000243]", "Peptidase family M49 [IPR039461]", "Peptidase, FtsH [IPR005936]", "Peptide chain release factor eRF1/aRF1 [IPR004403]", "Peptidyl-prolyl cis-trans isomerase E [IPR016304]", "Peptidyl-prolyl cis-trans isomerase FKBP2/11 [IPR044609]", "Peptidyl-prolyl cis-trans isomerase FKBP3 [IPR043368]", "Peptidyl-prolyl cis-trans isomerase FKBP4 [IPR031212]", "Peptidyl-prolyl cis-trans isomerase FKBP5 [IPR031210]", "Peptidyl-prolyl cis-trans isomerase PIN4 [IPR043323]", "Peptidyl-tRNA hydrolase, PTH2 [IPR002833]", "Pericentriolar material 1 protein [IPR024138]", "Perilipin [IPR004279]", "Periodic tryptophan protein 1 [IPR044285]", "Periodic tryptophan protein 2 [IPR027145]", "Periphilin-1 [IPR028851]", "Peroxin-3 [IPR006966]", "Peroxiredoxin, AhpC-type [IPR024706]", "Peroxiredoxin-5-like [IPR037944]", "Peroxiredoxin-like 2A [IPR032802]", "Peroxiredoxin-like 2A/B/C [IPR032801]", "Peroxisomal acyl-coenzyme A oxidase [IPR034171]", "Peroxisomal membrane protein 14 [IPR025655]", "Peroxisomal targeting signal 1 receptor PEX5, animals [IPR024113]", "Peroxisome membrane protein, Pex16 [IPR013919]", "Peroxysomal long chain fatty acyl transporter [IPR005283]", "Pescadillo [IPR010613]", "Pex19 protein [IPR006708]", "Phenylalanine-tRNA ligase, class IIc, beta subunit [IPR045060]", "Phenylalanyl-tRNA synthetase, class IIc, alpha subunit [IPR004529]", "Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archael/eukaryotic type [IPR004531]", "Phosducin-like [IPR045037]", "Phosphatase Gpp1/Gpp2-like [IPR045228]", "Phosphatidate cytidylyltransferase [IPR000374]", "Phosphatidate cytidylyltransferase, eukaryota [IPR016720]", "Phosphatidate cytidylyltransferase, mitochondrial [IPR015222]", "Phosphatidyl serine synthase [IPR004277]", "Phosphatidylethanolamine-binding protein [IPR008914]", "Phosphatidylethanolamine-binding protein, eukaryotic [IPR035810]", "Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 [IPR042165]", "Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1-like [IPR044596]", "Phosphatidylinositol kinase [IPR015433]", "Phosphatidylinositol transfer protein [IPR001666]", "Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma [IPR016279]", "Phosphatidylinositol-4-phosphate 5-kinase [IPR023610]", "Phosphatidylinositol-binding clathrin assembly protein [IPR030412]", "Phosphatidylinositol-glycan biosynthesis class S protein [IPR019540]", "Phosphatidylserine decarboxylase [IPR033177]", "Phosphatidylserine decarboxylase, eukaryotic type 1 [IPR033661]", "Phosphatidylserine decarboxylase-related [IPR003817]", "Phosphoacetylglucosamine mutase [IPR016657]", "Phosphodiesterase MJ0936/Vps29 [IPR000979]", "Phosphoenolpyruvate carboxykinase, GTP-utilising [IPR008209]", "Phosphoglucomutase [IPR045244]", "Phosphoglucose isomerase (PGI) [IPR001672]", "Phosphoglycerate kinase [IPR001576]", "Phosphoglycerate mutase 1 [IPR005952]", "Phosphoinositide phospholipase C family [IPR001192]", "Phospholipase B-like [IPR007000]", "Phospholipid-transporting ATPase IG [IPR030363]", "Phosphoribosylformylglycinamidine cyclo-ligase [IPR004733]", "Phosphoribosylformylglycinamidine synthase PurL [IPR010073]", "Phosphoribosylglycinamide formyltransferase [IPR004607]", "Phosphoribosylglycinamide synthetase [IPR000115]", "Phosphorylated adapter RNA export protein [IPR039047]", "Phosphoserine aminotransferase [IPR022278]", "Phosphotyrosyl phosphatase activator, PTPA [IPR004327]", "Pianissimo family [IPR028268]", "Pinin [IPR039853]", "Pirin [IPR012093]", "Plakin [IPR043197]", "Plakophilin/Delta catenin [IPR028435]", "Plasma membrane calcium-transporting ATPase 1 [IPR030320]", "Plasminogen activator inhibitor 1 RNA-binding protein [IPR027205]", "Plastin-1 [IPR030235]", "Plastin-2/3 [IPR039956]", "Plectin [IPR030269]", "Plexin family [IPR031148]", "Polo kinase kinase [IPR022165]", "Poly(A) polymerase [IPR014492]", "Poly(ADP-ribose) glycohydrolase [IPR007724]", "Poly-U binding splicing factor, PUF60-like [IPR006532]", "Polyadenylate binding protein, human types 1, 2, 3, 4 [IPR006515]", "Polyadenylate-binding protein 2 [IPR034911]", "Polyadenylate-binding protein-interacting protein 2-like [IPR040396]", "Polynucleotide kinase 3 phosphatase [IPR013954]", "Polyprenyl synthetase [IPR000092]", "Polyribonucleotide 5-hydroxyl-kinase Clp1/Grc3 [IPR045116]", "Polyribonucleotide nucleotidyltransferase [IPR012162]", "Porin, eukaryotic type [IPR001925]", "Porphobilinogen deaminase [IPR000860]", "Pre-mRNA 3' end processing protein Pfs2-like [IPR045245]", "Pre-mRNA-processing factor 17 [IPR032847]", "Pre-mRNA-processing factor 19 [IPR038959]", "Pre-mRNA-processing factor 6/Prp1/STA1 [IPR027108]", "Pre-mRNA-processing factor Prp40 [IPR039726]", "Pre-mRNA-processing-splicing factor 8 [IPR027652]", "Pre-mRNA-splicing factor Cwf15/Cwc15 [IPR006973]", "Pre-mRNA-splicing factor 38 [IPR005037]", "Pre-mRNA-splicing factor Cwc2/Slt11 [IPR039171]", "Pre-mRNA-splicing factor Isy1 [IPR009360]", "Pre-mRNA-splicing factor SPF27 [IPR008409]", "Pre-mRNA-splicing factor Spp2-like [IPR045166]", "Pre-mRNA-splicing factor Syf1-like [IPR045075]", "Pre-mRNA-splicing regulator WTAP [IPR033757]", "Pre-rRNA-processing protein Esf1 [IPR039754]", "Pre-rRNA-processing protein PNO1-like [IPR039912]", "Pre-rRNA-processing protein TSR2 [IPR019398]", "Prefoldin alpha subunit, archaea-type [IPR011599]", "Prefoldin alpha-like [IPR004127]", "Prefoldin beta-like [IPR002777]", "Prefoldin subunit 2 [IPR027235]", "Prefoldin subunit 3 [IPR016655]", "Prenylated rab acceptor PRA1 [IPR004895]", "Prenylcysteine oxidase [IPR017046]", "Presenilin/signal peptide peptidase [IPR006639]", "Primosome PriB/single-strand DNA-binding [IPR000424]", "Probable E3 ubiquitin-protein ligase makorin-2 [IPR026293]", "Probable methyltransferase TARBP1 [IPR025806]", "Probable methyltransferase Trm3/TARBP1 [IPR045330]", "Probable ubiquitin carboxyl-terminal hydrolase FAF-X [IPR031226]", "Profilin [IPR005455]", "Profilin-1 [IPR029892]", "Profilin-2 [IPR029891]", "Profilin1/2/3, vertebrate [IPR005454]", "Progesterone-induced-blocking factor 1 [IPR026205]", "Programmed cell death protein 4 [IPR039778]", "Prohibitin [IPR000163]", "Proliferating cell nuclear antigen, PCNA [IPR000730]", "Proline-rich AKT1 substrate 1 protein [IPR026682]", "Proline-tRNA ligase, class IIa, archaeal-type [IPR004499]", "Prolyl 3-hydroxylase 1 [IPR039837]", "Prolyl 3-hydroxylase 3 [IPR039839]", "Prolyl 3-hydroxylase [IPR039575]", "Prolyl 4-hydroxylase [IPR045054]", "Prostaglandin E synthase 2 [IPR034334]", "Prostaglandin reductase 2 [IPR037399]", "Prostate apoptosis response 4 [IPR026117]", "Proteasomal ubiquitin receptor Rpn13/ADRM1 [IPR006773]", "Proteasome B-type subunit [IPR023333]", "Proteasome activator PA28 [IPR009077]", "Proteasome activator complex subunit 4 [IPR035309]", "Proteasome alpha-type subunit [IPR023332]", "Proteasome assembly chaperone 1 [IPR016565]", "Proteasome assembly chaperone 2 [IPR019151]", "Proteasome assembly chaperone 2, eukaryotic [IPR016562]", "Proteasome assembly chaperone 3 [IPR018788]", "Proteasome beta 3 subunit [IPR033811]", "Proteasome component Ecm29 [IPR024372]", "Proteasome inhibitor PI31-like [IPR045128]", "Proteasome subunit alpha 1 [IPR035144]", "Proteasome subunit alpha 3 [IPR037555]", "Proteasome subunit alpha 7 [IPR035190]", "Proteasome subunit alpha2 [IPR034644]", "Proteasome subunit alpha4 [IPR034647]", "Proteasome subunit alpha5 [IPR033812]", "Proteasome subunit alpha6 [IPR034642]", "Proteasome subunit beta 1 [IPR035202]", "Proteasome subunit beta 2 [IPR035206]", "Proteasome subunit beta 4 [IPR016295]", "Proteasome subunit beta 5 [IPR037558]", "Proteasome subunit beta 6 [IPR035140]", "Proteasome subunit beta 7 [IPR035216]", "Proteasome, subunit alpha/beta [IPR001353]", "Protein AATF/Bfr2 [IPR039223]", "Protein BRAWNIN [IPR027858]", "Protein CIP2A [IPR042510]", "Protein CUSTOS [IPR026694]", "Protein Cms1 [IPR032704]", "Protein DEK [IPR044198]", "Protein ERGIC-53 [IPR033085]", "Protein FAM210A/B-like [IPR045866]", "Protein FAM3C [IPR039219]", "Protein FAM8A1 [IPR039871]", "Protein Hgh1 [IPR039717]", "Protein ICln/Lot5/Saf5 [IPR039924]", "Protein LYRIC [IPR031402]", "Protein LZIC [IPR040065]", "Protein Lsm12-like [IPR039683]", "Protein MMS22-like [IPR042320]", "Protein Mon2-like [IPR026829]", "Protein NDRG3 [IPR030692]", "Protein Nucling [IPR030227]", "Protein OS-9-like [IPR045149]", "Protein PBDC1, metazoa/fungi [IPR008476]", "Protein PRRC1 [IPR026534]", "Protein PRRC2 [IPR033184]", "Protein Peter Pan-like [IPR045112]", "Protein RCC2 [IPR028641]", "Protein Red-like [IPR039896]", "Protein S100-A10 [IPR028476]", "Protein S100-A11 [IPR028482]", "Protein S100-A13 [IPR028487]", "Protein SMG8 [IPR028802]", "Protein SMG9 [IPR039177]", "Protein SON [IPR032922]", "Protein Sgt1-like [IPR044563]", "Protein TFG [IPR033512]", "Protein XRP2 [IPR039093]", "Protein arginine N-methyltransferase PRMT5 [IPR007857]", "Protein arginine N-methyltransferase [IPR025799]", "Protein arginine methyltransferase NDUFAF7 [IPR003788]", "Protein canopy homolog [IPR042415]", "Protein disulfide-isomerase A6-like [IPR044569]", "Protein disulphide isomerase [IPR005792]", "Protein disulphide-isomerase A4 [IPR017068]", "Protein flightless-1 [IPR029919]", "Protein import receptor MAS20 [IPR002056]", "Protein import receptor MAS20, metazoan [IPR022422]", "Protein jagunal [IPR009787]", "Protein kinase C and casein kinase substrate in neurons protein 2 [IPR028521]", "Protein kinase C, delta [IPR027436]", "Protein kinase C, delta/epsilon/eta/theta types [IPR014376]", "Protein kinase C-binding protein 1 [IPR021931]", "Protein kinase Mps1 family [IPR027084]", "Protein kish [IPR009653]", "Protein of unknown function DUF1075 [IPR009432]", "Protein of unknown function DUF2046 [IPR019152]", "Protein of unknown function DUF3512 [IPR021900]", "Protein of unknown function DUF719 [IPR007998]", "Protein of unknown function DUF842, eukaryotic [IPR008560]", "Protein patched/dispatched [IPR003392]", "Protein phosphatase 1 regulatory subunit 12A/B/C [IPR017401]", "Protein phosphatase 2A regulatory subunit PR55 [IPR000009]", "Protein phosphatase 2A, regulatory B subunit, B56 [IPR002554]", "Protein phosphatase 2C family [IPR015655]", "Protein phosphatase 4 core regulatory subunit R2 [IPR015267]", "Protein phosphatase methylesterase, eukaryotic [IPR016812]", "Protein regulator of cytokinesis 1 [IPR032921]", "Protein spinster-like [IPR044770]", "Protein strawberry notch [IPR026741]", "Protein transport Sec61-beta/Sbh [IPR030671]", "Protein transport protein Got1 [IPR045176]", "Protein transport protein SEC31-like [IPR040251]", "Protein transport protein Sec23 [IPR037364]", "Protein transport protein SecG/Sec61-beta/Sbh [IPR016482]", "Protein virilizer [IPR026736]", "Protein wntless [IPR009551]", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase [IPR000682]", "Protein-S-isoprenylcysteine O-methyltransferase [IPR025770]", "Protein-glutamate O-methyltransferase [IPR039763]", "Protein-tyrosine phosphatase, low molecular weight [IPR017867]", "Protein-tyrosine phosphatase, low molecular weight, mammalian [IPR002115]", "Protein-tyrosine phosphatase, non-receptor type-1/2 [IPR012265]", "Protein-tyrosine phosphatase, non-receptor type-6, -11 [IPR012152]", "Protein-tyrosine phosphatase-like, PTPLA [IPR007482]", "Protein/nucleic acid deglycase DJ-1 [IPR006287]", "Proteinase inhibitor I25A, stefin [IPR001713]", "Proto-oncogene c-Rel [IPR030505]", "Protocadherin-19 [IPR030716]", "Protoporphyrinogen oxidase [IPR004572]", "Pseudouridine synthase I, TruA [IPR001406]", "Pseudouridine synthase PUS1/ PUS2-like [IPR041708]", "Pseudouridine synthase, TruD [IPR001656]", "Pterin 4 alpha carbinolamine dehydratase [IPR001533]", "Pumilio homologue 3 [IPR040059]", "Purine 5'-nucleotidase [IPR016695]", "Purine nucleoside phosphorylase I, inosine/guanosine-specific [IPR011270]", "Purine nucleoside phosphorylase [IPR011268]", "Purine-rich element binding protein family [IPR006628]", "Purine-rich element-binding protein alpha [IPR030500]", "Putative RNA methyltransferase [IPR003750]", "Pyridine nucleotide-disulphide oxidoreductase, class I [IPR001100]", "Pyridoxal phosphate homeostasis protein [IPR011078]", "Pyridoxal phosphate-dependent decarboxylase [IPR002129]", "Pyridoxamine 5'-phosphate oxidase [IPR000659]", "Pyridoxine kinase [IPR004625]", "Pyrimidine 5'-nucleotidase, eukaryotic [IPR006434]", "Pyrroline-5-carboxylate reductase [IPR000304]", "Pyruvate carboxylase [IPR005930]", "Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y [IPR017597]", "Pyruvate dehydrogenase E1 component subunit beta [IPR027110]", "Pyruvate kinase [IPR001697]", "Queuine tRNA-ribosyltransferase accessory subunit QTRTD1 [IPR028592]", "Quinone oxidoreductase-like protein 1 [IPR042633]", "RAB11-binding protein RELCH [IPR040362]", "RAD3/XPD family [IPR001945]", "RFT1 [IPR007594]", "RINT-1/Tip20 [IPR007528]", "RLI1 [IPR013283]", "RNA (C5-cytosine) methyltransferase [IPR023267]", "RNA (C5-cytosine) methyltransferase, NOP2 [IPR023273]", "RNA 3'-terminal phosphate cyclase [IPR000228]", "RNA 3'-terminal phosphate cyclase type 1 [IPR017770]", "RNA 3'-terminal phosphate cyclase type 2 [IPR016443]", "RNA binding protein Fox-1 [IPR017325]", "RNA binding protein HABP4/SERBP1 [IPR039764]", "RNA cytidine acetyltransferase NAT10 [IPR033688]", "RNA demethylase ALKBH5 [IPR032860]", "RNA exonuclease 4 [IPR034920]", "RNA methyltransferase Bin3-like [IPR039772]", "RNA polymerase I associated factor, A49-like [IPR009668]", "RNA polymerase II associated factor Paf1 [IPR007133]", "RNA polymerase II transcription factor SIII, subunit A [IPR010684]", "RNA polymerase II transcriptional coactivator Sub1/Tcp4-like [IPR045125]", "RNA polymerase II-associated protein RPAP1/Rba50 [IPR039913]", "RNA polymerase Rpc34 [IPR007832]", "RNA polymerase Rpc34-like [IPR016049]", "RNA polymerase subunit Rpb4/RPC9 [IPR005574]", "RNA polymerase subunit Rpb7-like [IPR045113]", "RNA polymerase-associated protein Ctr9 [IPR031101]", "RNA transcription, translation and transport factor protein [IPR019265]", "RNA-binding motif protein 8 [IPR008111]", "RNA-binding protein 10 [IPR033095]", "RNA-binding protein 26 [IPR034861]", "RNA-binding protein 26/27 [IPR045137]", "RNA-binding protein 5 [IPR033094]", "RNA-binding protein 6 [IPR028806]", "RNA-binding protein EWS [IPR033109]", "RNA-binding protein FUS [IPR034459]", "RNA-binding protein NOB1 [IPR039907]", "RNA-binding protein Nova-1 [IPR033086]", "RNA-binding protein Nova-2 [IPR033087]", "RNA-induced silencing complex, nuclease component Tudor-SN [IPR016685]", "RNA-splicing ligase RtcB homologue, eukaryotic [IPR027513]", "RNA-splicing ligase, RtcB [IPR001233]", "RNase P subunit p30 [IPR002738]", "ROK family [IPR000600]", "RPA-related protein RADX [IPR040893]", "RZZ complex, subunit Zw10 [IPR009361]", "Rab GDI protein [IPR000806]", "Rab GTPase-activating protein 1 [IPR033185]", "Rab-like protein 6 [IPR040385]", "Rab21 [IPR041833]", "Rab24 [IPR041828]", "Rab3 [IPR037872]", "Rab35 [IPR041815]", "Rab3GAP catalytic subunit [IPR045700]", "Rab3GAP regulatory subunit [IPR026059]", "Rab4 [IPR041819]", "Rab9 [IPR041824]", "Rabaptin [IPR003914]", "Rabaptin-5 [IPR029880]", "Rad21/Rec8-like protein [IPR039781]", "Ragulator complex protein LAMTOR2-like [IPR037587]", "Ragulator complex protein LAMTOR3 [IPR015019]", "RalBP1-associated Eps domain-containing protein 1 [IPR026814]", "Ran GTPase [IPR002041]", "Ran binding protein RanBP1-like [IPR045255]", "Rap guanine nucleotide exchange factor 2 [IPR030739]", "Rap1 GTPase-GDP dissociation stimulator 1 [IPR040144]", "Ras GTPase GNL1-like [IPR043358]", "Ras GTPase-activating protein-binding protein 1 [IPR034375]", "Ras GTPase-activating protein-binding protein 2 [IPR034377]", "Ras GTPase-activating protein-binding protein [IPR039539]", "Ras-like guanine nucleotide exchange factor [IPR008937]", "Ras-related protein Rab-23 [IPR034114]", "Ras-related protein Rab14 [IPR030702]", "Ras-related protein Ral [IPR028412]", "Ras-related protein Rap2 [IPR041840]", "Reduced folate carrier [IPR002666]", "Reduced folate transporter SLC19A1 [IPR028339]", "Regulatory associated protein of TOR [IPR004083]", "Remodeling and spacing factor 1-like [IPR028938]", "Remodelling complex subunit Rsc/polybromo [IPR037382]", "Replication factor A protein 1 [IPR004591]", "Replication factor A protein 2 [IPR014646]", "Replication factor A protein 3 [IPR013970]", "Replication factor A protein-like [IPR040260]", "Replication factor C subunit 1 [IPR012178]", "Replication termination factor 2 [IPR006735]", "Reticulon-4-interacting protein 1 [IPR037397]", "Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit [IPR017287]", "Retinoblastoma-binding protein 5/Swd1 [IPR037850]", "Retinoid X receptor/HNF4 [IPR000003]", "Retrieval of early ER protein Rer1 [IPR004932]", "Rho protein GDP-dissociation inhibitor [IPR000406]", "Rho-associated protein kinase 1/2 [IPR020684]", "Rho-related GTP-binding protein RhoG [IPR042734]", "Ribonuclease CAF1 [IPR006941]", "Ribonuclease H2, subunit A [IPR004649]", "Ribonuclease HII/HIII [IPR001352]", "Ribonuclease III [IPR011907]", "Ribonuclease Nob1, eukaryote [IPR017117]", "Ribonuclease P protein subunit Rpp29/RNP1 [IPR002730]", "Ribonuclease P protein subunit Rpp38 [IPR042848]", "Ribonuclease P/MRP subunit Rpp29 [IPR016848]", "Ribonuclease T2, eukaryotic [IPR033697]", "Ribonuclease T2-like [IPR001568]", "Ribonucleases P/MRP protein subunit Pop1 [IPR039182]", "Ribonucleoprotein PTB-binding 1 [IPR034635]", "Ribonucleoside-diphosphate reductase large subunit [IPR039718]", "Ribonucleotide reductase small subunit [IPR033909]", "Ribonucleotide reductase small subunit family [IPR000358]", "Ribophorin I [IPR007676]", "Ribose-phosphate pyrophosphokinase [IPR005946]", "Ribosomal RNA adenine dimethylase [IPR011530]", "Ribosomal RNA adenine methyltransferase KsgA/Erm [IPR001737]", "Ribosomal RNA assembly KRR1 [IPR024166]", "Ribosomal RNA large subunit methyltransferase E [IPR015507]", "Ribosomal RNA processing protein 8 [IPR007823]", "Ribosomal RNA small subunit methyltransferase H [IPR002903]", "Ribosomal RNA-processing protein 15 [IPR012459]", "Ribosomal RNA-processing protein Rrp9-like [IPR039241]", "Ribosomal biogenesis NSA2 family [IPR039411]", "Ribosomal biogenesis factor [IPR031389]", "Ribosomal biogenesis regulatory protein [IPR007023]", "Ribosomal biogenesis, methyltransferase, EMG1/NEP1 [IPR005304]", "Ribosomal export protein Nmd3 [IPR039768]", "Ribosomal protein L1 [IPR002143]", "Ribosomal protein L1, mitochondrial [IPR005879]", "Ribosomal protein L1/ribosomal biogenesis protein [IPR028364]", "Ribosomal protein L10P [IPR001790]", "Ribosomal protein L10e [IPR001197]", "Ribosomal protein L11, bacterial-type [IPR006519]", "Ribosomal protein L11/L12 [IPR000911]", "Ribosomal protein L12/P1/P2 family [IPR027534]", "Ribosomal protein L13 [IPR005822]", "Ribosomal protein L13, bacterial-type [IPR005823]", "Ribosomal protein L13, eukaryotic/archaeal [IPR005755]", "Ribosomal protein L13e [IPR001380]", "Ribosomal protein L14 [IPR039660]", "Ribosomal protein L14P [IPR000218]", "Ribosomal protein L15 [IPR030878]", "Ribosomal protein L15, bacterial-type [IPR005749]", "Ribosomal protein L15e [IPR000439]", "Ribosomal protein L17 [IPR000456]", "Ribosomal protein L18e [IPR000039]", "Ribosomal protein L19 [IPR001857]", "Ribosomal protein L2 [IPR002171]", "Ribosomal protein L2, archaeal-type [IPR023672]", "Ribosomal protein L20 [IPR005813]", "Ribosomal protein L21 [IPR001787]", "Ribosomal protein L21-like [IPR028909]", "Ribosomal protein L21e [IPR001147]", "Ribosomal protein L22/L17 [IPR001063]", "Ribosomal protein L22/L17, eukaryotic/archaeal [IPR005721]", "Ribosomal protein L22e [IPR002671]", "Ribosomal protein L23 [IPR019985]", "Ribosomal protein L24 [IPR003256]", "Ribosomal protein L24e-related [IPR000988]", "Ribosomal protein L25/L23 [IPR013025]", "Ribosomal protein L26/L24, eukaryotic/archaeal [IPR005756]", "Ribosomal protein L27e [IPR001141]", "Ribosomal protein L28/L24 [IPR026569]", "Ribosomal protein L28/L40, mitochondrial [IPR019192]", "Ribosomal protein L28e [IPR002672]", "Ribosomal protein L29/L35 [IPR001854]", "Ribosomal protein L29e [IPR002673]", "Ribosomal protein L3 [IPR000597]", "Ribosomal protein L3, archaeal/eukaryotic type [IPR045077]", "Ribosomal protein L3, bacterial/organelle-type [IPR019927]", "Ribosomal protein L30/YlxQ [IPR039109]", "Ribosomal protein L30e [IPR000231]", "Ribosomal protein L31e [IPR000054]", "Ribosomal protein L32e [IPR001515]", "Ribosomal protein L34Ae [IPR008195]", "Ribosomal protein L35A [IPR001780]", "Ribosomal protein L36e [IPR000509]", "Ribosomal protein L37/S30 [IPR010793]", "Ribosomal protein L37ae [IPR002674]", "Ribosomal protein L37e [IPR001569]", "Ribosomal protein L38e [IPR002675]", "Ribosomal protein L4, eukaryotic and archaeal type [IPR045240]", "Ribosomal protein L4/L1e [IPR002136]", "Ribosomal protein L44e [IPR000552]", "Ribosomal protein L47, mitochondrial [IPR010729]", "Ribosomal protein L49/IMG2 [IPR007740]", "Ribosomal protein L5 [IPR002132]", "Ribosomal protein L5 eukaryotic/L18 archaeal [IPR005485]", "Ribosomal protein L50, mitochondria [IPR018305]", "Ribosomal protein L53, mitochondrial [IPR019716]", "Ribosomal protein L55, mitochondrial [IPR018615]", "Ribosomal protein L6 [IPR000702]", "Ribosomal protein L7, eukaryotic [IPR005998]", "Ribosomal protein L7/L12 [IPR000206]", "Ribosomal protein L7/L30 [IPR039699]", "Ribosomal protein L7A/L8 [IPR001921]", "Ribosomal protein L7Ae/L8/Nhp2 family [IPR018492]", "Ribosomal protein L9 [IPR000244]", "Ribosomal protein P2 [IPR044076]", "Ribosomal protein S10 [IPR001848]", "Ribosomal protein S10, eukaryotic/archaeal [IPR005729]", "Ribosomal protein S11 [IPR001971]", "Ribosomal protein S12/S23 [IPR006032]", "Ribosomal protein S12e [IPR000530]", "Ribosomal protein S13 [IPR001892]", "Ribosomal protein S14 [IPR001209]", "Ribosomal protein S15 [IPR000589]", "Ribosomal protein S15, bacterial-type [IPR005290]", "Ribosomal protein S15P [IPR023029]", "Ribosomal protein S16 [IPR000307]", "Ribosomal protein S17, archaeal/eukaryotic [IPR028333]", "Ribosomal protein S17/S11 [IPR000266]", "Ribosomal protein S17e [IPR001210]", "Ribosomal protein S18 [IPR001648]", "Ribosomal protein S19/S15 [IPR002222]", "Ribosomal protein S19A/S15e [IPR005713]", "Ribosomal protein S19e [IPR001266]", "Ribosomal protein S2 [IPR001865]", "Ribosomal protein S2, bacteria/mitochondria/plastid [IPR005706]", "Ribosomal protein S2, eukaryotic [IPR027498]", "Ribosomal protein S2, eukaryotic/archaeal [IPR005707]", "Ribosomal protein S21e [IPR001931]", "Ribosomal protein S22, mitochondrial [IPR019374]", "Ribosomal protein S23, eukaryotic/archaeal [IPR005680]", "Ribosomal protein S23, mitochondrial [IPR019520]", "Ribosomal protein S23/S29, mitochondrial [IPR019368]", "Ribosomal protein S24/S35, mitochondrial [IPR039848]", "Ribosomal protein S24e [IPR001976]", "Ribosomal protein S25 [IPR004977]", "Ribosomal protein S26e [IPR000892]", "Ribosomal protein S28, mitochondrial [IPR019375]", "Ribosomal protein S28e [IPR000289]", "Ribosomal protein S29, mitochondrial [IPR008092]", "Ribosomal protein S3, eukaryotic/archaeal [IPR005703]", "Ribosomal protein S30 [IPR006846]", "Ribosomal protein S30, mitochondrial [IPR039982]", "Ribosomal protein S3Ae [IPR001593]", "Ribosomal protein S4/S9 [IPR022801]", "Ribosomal protein S4/S9, eukaryotic/archaeal [IPR005710]", "Ribosomal protein S4e [IPR000876]", "Ribosomal protein S5 [IPR000851]", "Ribosomal protein S5, eukaryotic/archaeal [IPR005711]", "Ribosomal protein S5/S7 [IPR000235]", "Ribosomal protein S5/S7, eukaryotic/archaeal [IPR005716]", "Ribosomal protein S6 kinase II [IPR016239]", "Ribosomal protein S6, eukaryotic [IPR014401]", "Ribosomal protein S6e [IPR001377]", "Ribosomal protein S7e [IPR000554]", "Ribosomal protein S8 [IPR000630]", "Ribosomal protein S8e [IPR001047]", "Ribosomal protein S8e/ribosomal biogenesis NSA2 [IPR022309]", "Ribosomal protein S9 [IPR000754]", "Ribosome assembly factor Mrt4 [IPR033867]", "Ribosome biogenesis factor, NIP7 [IPR016686]", "Ribosome biogenesis protein BRX1 [IPR026532]", "Ribosome biogenesis protein Bms1/Tsr1 [IPR039761]", "Ribosome biogenesis protein Nop16 [IPR019002]", "Ribosome biogenesis protein Nop53/GLTSCR2 [IPR011687]", "Ribosome biogenesis protein Rpf2 [IPR039770]", "Ribosome maturation protein Sdo1/SBDS [IPR002140]", "Ribosome maturation protein Sdo1/SBDS-like [IPR039100]", "Ribosome recycling factor [IPR002661]", "Ribosome-binding ATPase YchF/Obg-like ATPase 1 [IPR004396]", "Ribosome-binding protein 1 [IPR040248]", "RidA family [IPR006056]", "Rieske iron-sulphur protein [IPR014349]", "Root UVB sensitive family [IPR006968]", "RuvB-like [IPR027238]", "RuvB-like helicase 1 [IPR037938]", "RuvB-like helicase 2 [IPR037942]", "S-adenosylmethionine synthetase [IPR002133]", "S-formylglutathione hydrolase [IPR014186]", "S-phase kinase-associated protein 1 [IPR016897]", "S-phase kinase-associated protein 1-like [IPR001232]", "SAC3/GANP/THP3 [IPR045107]", "SAFB-like transcription modulator [IPR034780]", "SAP30-binding protein [IPR012479]", "SCAMP [IPR007273]", "SCAR/WAVE family [IPR028288]", "SERRATE/Ars2 [IPR039727]", "SH3 and PX domain-containing protein 2B [IPR030512]", "SH3-binding, glutamic acid-rich protein [IPR006993]", "SHC SH2 domain-binding protein 1-like [IPR045140]", "SHC-transforming protein 1 [IPR029586]", "SIKE family [IPR008555]", "SIT4 phosphatase-associated protein family [IPR007587]", "SKI-interacting protein, SKIP [IPR017862]", "SLC12A transporter family [IPR004842]", "SNF5/SMARCB1/INI1 [IPR006939]", "SNU66/SART1 family [IPR005011]", "SNX17/27/31 [IPR037831]", "SOS response associated peptidase (SRAP) [IPR003738]", "SOUL haem-binding protein [IPR006917]", "SPIN90/Ldb17 [IPR030125]", "SPRY domain-containing protein 7 [IPR035766]", "SSNA1 family [IPR033362]", "SUMO-activating enzyme subunit Uba2 [IPR030661]", "SUN domain-containing protein 1 [IPR018539]", "SUN domain-containing protein 1-5 [IPR045119]", "SUN domain-containing protein 2 [IPR030272]", "SURP and G-patch domain-containing protein 1/2 [IPR040169]", "SWI/SNF complex subunit BAF57 [IPR030089]", "SWI/SNF complex subunit BRG1 [IPR030100]", "SWI/SNF complex subunit SMARCC1 [IPR030087]", "SWI/SNF complex subunit SMARCC2 [IPR038044]", "SWI/SNF-like complex subunit BAF250a [IPR030094]", "SWI/SNF-like complex subunit BAF250/Osa [IPR021906]", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 [IPR038041]", "SWR1-complex protein 4/DNA methyltransferase 1-associated protein 1 [IPR027109]", "SWR1-complex protein 5/Craniofacial development protein 1/2 [IPR027124]", "Saposin [IPR008373]", "Saposin, chordata [IPR021165]", "Sarcolemmal membrane-associated protein [IPR030498]", "Sas10/Utp3/C1D [IPR007146]", "Scaffold attachment factor B1 [IPR034781]", "Scaffold attachment factor B2 [IPR034782]", "Scavenger mRNA decapping enzyme DcpS/DCS2 [IPR008594]", "Scc2/Nipped-B family [IPR033031]", "Schlafen family [IPR029684]", "Sda1 [IPR027312]", "Sec1-like protein [IPR001619]", "Sec13/Seh1 family [IPR037363]", "Sec20 [IPR005606]", "SecY/SEC61-alpha family [IPR002208]", "Selenophosphate synthetase [IPR004536]", "Sentrin-specific protease 3 [IPR037945]", "Sepiapterin reductase [IPR006393]", "Septin 2 [IPR008113]", "Septin 6 [IPR030644]", "Septin 7 [IPR008115]", "Septin 8 [IPR030646]", "Septin 9 [IPR030645]", "Septin [IPR016491]", "Septin and tuftelin interacting protein [IPR024933]", "Serine hydroxymethyltransferase [IPR001085]", "Serine-tRNA ligase, type1 [IPR002317]", "Serine/arginine-rich splicing factor 10 [IPR034476]", "Serine/arginine-rich splicing factor 11 [IPR034447]", "Serine/arginine-rich splicing factor 6 [IPR029541]", "Serine/threonine protein phosphatase 5 [IPR011236]", "Serine/threonine-protein kinase MARK3 [IPR033628]", "Serine/threonine-protein kinase OSR1 [IPR028749]", "Serine/threonine-protein kinase PAK2 [IPR035065]", "Serine/threonine-protein kinase RAC alpha [IPR039027]", "Serine/threonine-protein kinase TOR [IPR026683]", "Serine/threonine-protein kinase Vps15-like [IPR045162]", "Serine/threonine-protein phosphatase 2A subunit A, metazoa [IPR031090]", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit [IPR037979]", "Serpin H1 [IPR033547]", "Serpin family [IPR000215]", "Shootin-1 [IPR024849]", "Short transmembrane mitochondrial protein 1 [IPR027854]", "Short-chain dehydrogenase/reductase SDR [IPR002347]", "Sialidase family [IPR026856]", "Sideroflexin-4 [IPR028825]", "Sigma intracellular receptor 2 [IPR016964]", "Signal peptidase complex catalytic subunit SEC11A [IPR037712]", "Signal peptidase complex subunit 3 [IPR007653]", "Signal peptidase complex subunit Spc2/SPCS2 [IPR009582]", "Signal recognition particle SRP9 [IPR039914]", "Signal recognition particle receptor, beta subunit [IPR019009]", "Signal recognition particle subunit SRP68 [IPR026258]", "Signal recognition particle, SRP14 subunit [IPR003210]", "Signal recognition particle, SRP19 subunit [IPR002778]", "Signal recognition particle, SRP54 subunit [IPR022941]", "Signal recognition particle, SRP54 subunit, eukaryotic [IPR006325]", "Signal recognition particle, SRP72 subunit [IPR026270]", "Signal recognition particle, SRP9 subunit [IPR008832]", "Sin3 associated polypeptide p18 [IPR010516]", "Single-stranded DNA-binding protein [IPR011344]", "Sirtuin family [IPR003000]", "Sirtuin, class I [IPR017328]", "Sister chromatid cohesion protein Pds5 [IPR039776]", "Ski3/TTC37 [IPR039226]", "Slowmo/Ups family [IPR037365]", "Sm-like protein Lsm7 [IPR017132]", "Sm-like protein Lsm7/SmG [IPR044641]", "Smac/DIABLO protein [IPR015142]", "Small (40S) ribosomal subunit Asc1/RACK1 [IPR045223]", "Small GTPase Rho [IPR003578]", "Small GTPase [IPR001806]", "Small GTPase superfamily, ARF type [IPR024156]", "Small GTPase superfamily, ARF/SAR type [IPR006689]", "Small GTPase superfamily, SAR1-type [IPR006687]", "Small GTPase, Ras-type [IPR020849]", "Small nuclear ribonucleoprotein E [IPR027078]", "Small nuclear ribonucleoprotein Sm D2 [IPR027248]", "Small nuclear ribonucleoprotein Sm D3 [IPR034099]", "Small-subunit processome, Utp11 [IPR007144]", "Small-subunit processome, Utp14 [IPR006709]", "Smg8/Smg9 [IPR019354]", "Smooth muscle protein/calponin [IPR003096]", "Snf7 family [IPR005024]", "Sodium/potassium-transporting ATPase subunit beta [IPR000402]", "Sodium/potassium-transporting ATPase subunit beta, chordates [IPR015565]", "Sodium/solute symporter [IPR001734]", "Sodium:dicarboxylate symporter [IPR001991]", "Sodium:neurotransmitter symporter [IPR000175]", "Solute carrier family 12 member 1/2 [IPR002443]", "Solute carrier family 12 member 2 [IPR002444]", "Solute carrier family 35 member SLC35F1/F2/F6 [IPR009262]", "Sorbitol dehydrogenase-like [IPR045306]", "Sororin protein [IPR018605]", "Sorting nexin 9 family [IPR014536]", "Sorting nexin-1 [IPR028660]", "Sorting nexin-17 [IPR028666]", "Sorting nexin-2 [IPR028653]", "Sorting nexin-27 [IPR028667]", "Sorting nexin-5 [IPR028654]", "Sorting nexin-5/6/32 [IPR014637]", "Sorting nexin-6 [IPR028657]", "Sorting nexin-9 [IPR028644]", "Spartin-like [IPR045036]", "Spectrin, beta subunit [IPR016343]", "Sperm-associated antigen 5 [IPR028728]", "Spermatid perinuclear RNA-binding protein [IPR030446]", "Spermidine/spermine synthase, eukaryotes [IPR030668]", "Spermidine/spermine synthases [IPR001045]", "Sphingomyelin phosphodiesterase 4 [IPR024129]", "Sphingosine N-acyltransferase Lag1/Lac1-like [IPR016439]", "Splicing factor 3A subunit 1 [IPR045146]", "Splicing factor 3A subunit 3 [IPR031776]", "Splicing factor 3B subunit 1-like [IPR038737]", "Splicing factor 3B subunit 5/RDS3 complex subunit 10 [IPR009846]", "Splicing factor 3B, subunit 5 [IPR017089]", "Splicing factor 45 [IPR040052]", "Splicing factor ELAV/Hu [IPR006548]", "Splicing factor, RBM39-like [IPR006509]", "Splicing factor, arginine/serine-rich 19 [IPR042841]", "Squalene cyclase [IPR018333]", "Squalene monooxygenase [IPR040125]", "Squalene synthase-like [IPR006449]", "Squalene/phytoene synthase [IPR002060]", "Stathmin family [IPR000956]", "Sterile alpha and TIR motif-containing protein 1 [IPR039184]", "Steroidogenic acute regulatory protein-like [IPR000799]", "Sterol O-acyltransferase, ACAT/DAG/ARE types [IPR014371]", "Sterol O-acyltransferase, metazoa [IPR030687]", "Sterol transport protein NPC2-like [IPR039670]", "Stomatin [IPR028515]", "Stomatin/HflK/HflC family [IPR001972]", "Structural maintenance of chromosomes flexible hinge domain-containing protein 1 [IPR038892]", "Structural maintenance of chromosomes protein 1A, metazoan [IPR029683]", "Structural maintenance of chromosomes protein 5 [IPR027131]", "Structural maintenance of chromosomes protein [IPR024704]", "Structure-specific recognition protein [IPR000969]", "Succinate dehydrogenase, flavoprotein subunit [IPR011281]", "Succinate dehydrogenase/fumarate reductase iron-sulphur protein [IPR004489]", "Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [IPR014006]", "Succinate semialdehyde dehydrogenase [IPR010102]", "Succinate--CoA synthetase, beta subunit [IPR005809]", "Succinyl-CoA ligase, alpha subunit [IPR005810]", "Sulfhydryl oxidase [IPR039798]", "Sulfotransferase [IPR005331]", "Sulfurtransferase TST/MPST-like [IPR045078]", "Suppressor of hairless-like [IPR040159]", "Suppressor of white apricot [IPR040397]", "Surface antigen D15-like [IPR039910]", "Surfeit locus 1/4 [IPR045214]", "Surfeit locus 4 [IPR002995]", "Surfeit locus 6 [IPR007019]", "Symplekin/Pta1 [IPR021850]", "Synaptic vesicle protein SV2 [IPR022308]", "Synaptobrevin [IPR001388]", "Synaptogyrin [IPR016579]", "Syntaxin [IPR045242]", "Syntaxin-3 [IPR031186]", "Syntenin-1 [IPR030528]", "Synthesis of cytochrome c oxidase, Sco1/Sco2 [IPR017276]", "T-complex protein 1, alpha subunit [IPR012715]", "T-complex protein 1, beta subunit [IPR012716]", "T-complex protein 1, delta subunit [IPR012717]", "T-complex protein 1, epsilon subunit [IPR012718]", "T-complex protein 1, eta subunit [IPR012720]", "T-complex protein 1, gamma subunit [IPR012719]", "T-complex protein 1, theta subunit [IPR012721]", "T-complex protein 1, zeta subunit [IPR012722]", "TAF15/EWS/TLS family [IPR034870]", "TAP46-like protein [IPR007304]", "TATA binding associated factor 15 [IPR034875]", "TATA element modulatory factor 1 DNA binding [IPR022092]", "TB2/DP1/HVA22-related protein [IPR004345]", "TCF25/Rqc1 [IPR006994]", "TE2IP/Rap1 [IPR039595]", "TFP11/STIP/Ntr1 [IPR045211]", "TH1 protein [IPR006942]", "THO complex subunit 2 [IPR040007]", "THO complex subunit 6 [IPR042626]", "THO complex, subunit 5 [IPR019163]", "THO complex, subunit THOC1 [IPR021861]", "THRAP3/BCLAF1 family [IPR029199]", "THUMP domain-containing protein 1-like [IPR040183]", "TMEM14 family [IPR005349]", "TMEM192 family [IPR029399]", "TMEM33/Pom33 family [IPR005344]", "TMEM70 family [IPR009724]", "TMEM70/TMEM186/TMEM223 protein family [IPR045325]", "TMEM85/ER membrane protein complex subunit 4 [IPR009445]", "TOX high mobility group box family member 4 [IPR037985]", "TPP-binding domain containing protein HACL1-like [IPR045025]", "TPX2 [IPR009675]", "TRAPP I complex, subunit 5 [IPR016696]", "TRAPP III complex, Trs85 [IPR024420]", "TREX component Tex1/THOC3 [IPR040132]", "TRIC channel [IPR007866]", "Tankyrase 1-binding protein-like [IPR040006]", "Target of Myb protein 1 [IPR014645]", "TatSF1-like [IPR034393]", "Taxilin family [IPR026183]", "Telomere-associated protein Rif1 [IPR028566]", "Teneurin-3/4 [IPR027691]", "Testin [IPR027683]", "Testis-expressed protein 10/pre-rRNA-processing protein Ipi1 [IPR037947]", "Tetrahydrofolate dehydrogenase/cyclohydrolase [IPR000672]", "Tetraspanin, animals [IPR000301]", "Tetraspanin/Peripherin [IPR018499]", "Tetratricopeptide repeat protein 19 [IPR040395]", "Tetratricopeptide repeat protein 21A/21B [IPR040364]", "Tetratricopeptide repeat protein 26 [IPR030511]", "Tetratricopeptide repeat protein 38 [IPR033891]", "Tetratricopeptide repeat protein TTC27/Emw1 [IPR044244]", "The Golgi pH regulator/GPCR-type G protein [IPR015672]", "The WD repeat Cdc20/Fizzy family [IPR033010]", "ThiF/MoeB/HesA family [IPR045886]", "Thiamine pyrophosphate enzyme [IPR045229]", "Thiolase [IPR002155]", "Thioredoxin domain-containing protein 16 [IPR040090]", "Thioredoxin domain-containing protein 17-like [IPR045108]", "Thioredoxin-related transmembrane protein 2 [IPR039101]", "Thioredoxin/glutathione reductase selenoprotein [IPR006338]", "Threonine-tRNA ligase, class IIa [IPR002320]", "Thymidine kinase [IPR001267]", "Thymidylate kinase [IPR018094]", "Thymidylate synthase [IPR000398]", "Thymidylate synthase/dCMP hydroxymethylase [IPR045097]", "Thyroid hormone receptor-associated protein 3 [IPR026667]", "Tight junction protein ZO [IPR005417]", "Tight junction protein ZO-1 [IPR005418]", "Tight junction protein ZO-2 [IPR005419]", "Tim23-like [IPR045238]", "Tim44-like [IPR039544]", "Timeless [IPR044998]", "Tissue alpha-L-fucosidase [IPR028755]", "TmcA/NAT10/Kre33 [IPR032672]", "Tom40 [IPR037930]", "Torsin 1/2 [IPR017378]", "Torsin [IPR010448]", "Torsin-1A [IPR030549]", "Torsin-1A-interacting protein 1/2 [IPR008662]", "Torsin-1B [IPR030550]", "TraB/PrgY/GumN family [IPR002816]", "Trafficking protein particle complex subunit [IPR007233]", "Trans-isoprenyl diphosphate synthases, eukaryotic-type [IPR044844]", "Transaldolase type 1 [IPR004730]", "Transaldolase/Fructose-6-phosphate aldolase [IPR001585]", "Transcription elongation factor SPT5 [IPR039659]", "Transcription elongation factor Spt5, eukaryote [IPR017071]", "Transcription elongation factor Spt6 [IPR017072]", "Transcription elongation factor, IIS-type [IPR035100]", "Transcription elongation factor, TFIIS [IPR006289]", "Transcription elongation regulator 1-like [IPR045148]", "Transcription facto Tfc3-like [IPR044210]", "Transcription factor BTF3 [IPR039370]", "Transcription factor E [IPR039997]", "Transcription factor II-I [IPR016659]", "Transcription factor IIIC subunit Tfc1/Sfc1 [IPR040454]", "Transcription factor STAT [IPR001217]", "Transcription factor TFIIB [IPR000812]", "Transcription factor Tfc4/TFIIIC-102/Sfc4 [IPR039340]", "Transcription initiation factor IIF, alpha subunit [IPR008851]", "Transcription initiation factor IIF, beta subunit [IPR003196]", "Transcription initiation factor TFIID component TAF4 [IPR045144]", "Transcription initiation factor TFIID subunit 7 [IPR037817]", "Transcription intermediary factor 1-beta [IPR037373]", "Transcription-associated protein 1 [IPR033317]", "Transcriptional regulator TACO1-like [IPR002876]", "Transcriptional regulatory protein Sin3-like [IPR039774]", "Transcriptional regulatory protein Sin3a [IPR037969]", "Transcriptional repressor p66 [IPR040386]", "Transducin beta-like protein 2 [IPR042410]", "Transferrin receptor protein 1 [IPR029513]", "Transforming growth factor-beta-related [IPR015615]", "Transgelin-2 [IPR001061]", "Translation Initiation factor eIF- 4e [IPR001040]", "Translation elongation factor EF1A, eukaryotic/archaeal [IPR004539]", "Translation elongation factor EFG/EF2 [IPR004540]", "Translation elongation factor EFTs/EF1B [IPR001816]", "Translation elongation factor EFTu/EF1A, bacterial/organelle [IPR004541]", "Translation elongation factor IF5A-like [IPR001884]", "Translation initiation factor 2, alpha subunit [IPR011488]", "Translation initiation factor 2A [IPR011387]", "Translation initiation factor 3 complex subunit L [IPR019382]", "Translation initiation factor IF- 2 [IPR015760]", "Translation initiation factor IF2/IF5 [IPR045196]", "Translation initiation factor IF6 [IPR002769]", "Translation initiation factor aIF-2, bacterial-like [IPR000178]", "Translation machinery-associated protein 16 [IPR021346]", "Translational activator Gcn1 [IPR033173]", "Translationally controlled tumour protein [IPR018105]", "Translin [IPR033956]", "Translin family [IPR002848]", "Translocation associated membrane protein [IPR016447]", "Translocation protein Sec62 [IPR004728]", "Translocation protein Sec63 [IPR027137]", "Translocator protein [IPR030164]", "Translocon-associated [IPR008855]", "Translocon-associated protein (TRAP), alpha subunit [IPR005595]", "Transmembrane emp24 domain-containing protein 5 [IPR015717]", "Transmembrane emp24 domain-containing protein [IPR015720]", "Transmembrane protein 109 [IPR039492]", "Transmembrane protein 11 [IPR026120]", "Transmembrane protein 126 [IPR009801]", "Transmembrane protein 160 [IPR026801]", "Transmembrane protein 177 [IPR026620]", "Transmembrane protein 201 [IPR040041]", "Transmembrane protein 205 [IPR042623]", "Transmembrane protein 214 [IPR019308]", "Transmembrane protein 43 family [IPR012430]", "Transmembrane protein GPR107/GPR108-like [IPR009637]", "Transport protein particle (TRAPP) component [IPR007194]", "Treacle protein [IPR017859]", "Tricarboxylate/iron carrier [IPR004686]", "Trimethyllysine dioxygenase [IPR012776]", "Triosephosphate isomerase [IPR000652]", "Triosephosphate isomerase, bacterial/eukaryotic [IPR022896]", "Trm112-like [IPR005651]", "Tropomodulin [IPR004934]", "Tropomodulin-1 [IPR030135]", "Tropomodulin-3 [IPR030133]", "Tropomyosin [IPR000533]", "Tryptophan-tRNA ligase [IPR002306]", "Tryptophan-tRNA ligase, bacterial-type [IPR024109]", "TspO/MBR-related protein [IPR004307]", "Tuberin [IPR003913]", "Tuberin/Ral GTPase-activating protein subunit alpha [IPR027107]", "Tubulin [IPR000217]", "Tubulin binding cofactor A [IPR004226]", "Tubulin--tyrosine ligase-like protein 12 [IPR027749]", "Tubulin-folding cofactor D [IPR033162]", "Tubulin-specific chaperone E [IPR044994]", "Tubulin-tyrosine ligase/Tubulin polyglutamylase [IPR004344]", "Tumour protein D52 [IPR007327]", "Tweety [IPR006990]", "Twinfilin [IPR028458]", "Twinkle-like protein [IPR027032]", "Type 1 protein exporter [IPR039421]", "Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase [IPR002591]", "Type II pantothenate kinase [IPR004567]", "Type II phosphatidylinositol 4-kinase Lsb6/PI4K2 [IPR039756]", "Tyrosine protein kinase, EGF/ERB/XmrK receptor [IPR016245]", "Tyrosine-tRNA ligase [IPR002307]", "Tyrosine-tRNA ligase, bacterial-type [IPR024088]", "Tyrosine/threonine-protein kinase, Cdc2 inhibitor [IPR016235]", "U1 small nuclear ribonucleoprotein C [IPR017340]", "U2 auxiliary factor small subunit [IPR009145]", "U2 small nuclear ribonucleoprotein A' [IPR044640]", "U2 snRNP auxilliary factor, large subunit, splicing factor [IPR006529]", "U3 small nucleolar RNA-associated protein 10 [IPR040191]", "U3 small nucleolar RNA-associated protein 18 [IPR045161]", "U3 small nucleolar RNA-associated protein 25 [IPR010678]", "U3 small nucleolar RNA-associated protein 6 [IPR013949]", "U3 small nucleolar ribonucleoprotein complex, subunit Mpp10 [IPR012173]", "U3 snoRNP protein/Ribosome production factor 1 [IPR044281]", "U4/U6 small nuclear ribonucleoprotein Prp3 [IPR027104]", "U4/U6 small nuclear ribonucleoprotein Prp31 [IPR027105]", "U6 snRNA-associated Sm-like protein LSm2 [IPR016654]", "U6 snRNA-associated Sm-like protein Lsm1/8 [IPR044642]", "U6 snRNA-associated Sm-like protein Lsm3 [IPR040002]", "UAA transporter [IPR013657]", "UAP56-interacting factor [IPR009782]", "UBAP2/protein lingerer [IPR022166]", "UBX domain-containing protein 2/7 [IPR017346]", "UDP-N-acetylglucosamine 2-epimerase,UDP-hydrolysing [IPR020004]", "UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110kDa subunit [IPR037919]", "UDP-glucose 6-dehydrogenase, eukaryotic type [IPR028356]", "UDP-glucose/GDP-mannose dehydrogenase [IPR017476]", "UDP-glucose:Glycoprotein Glucosyltransferase [IPR009448]", "UDP-glucuronic acid decarboxylase [IPR044516]", "UDP-glucuronosyl/UDP-glucosyltransferase [IPR002213]", "UDP-sugar pyrophosphorylase [IPR039741]", "UDPGP family [IPR002618]", "UHRF1/2-like [IPR045134]", "UMP-CMP kinase [IPR006266]", "UPF0600 protein C5orf51 [IPR037657]", "USP39 [IPR033809]", "UTP--glucose-1-phosphate uridylyltransferase [IPR016267]", "UV excision repair protein Rad23 [IPR004806]", "Ubinuclein-2 [IPR026943]", "Ubiquilin-1/2 [IPR028430]", "Ubiquinol-cytochrome c chaperone, CBP3 [IPR007129]", "Ubiquinol-cytochrome c chaperone/UPF0174 [IPR021150]", "Ubiquinol-cytochrome-c reductase complex assembly factor 2 [IPR037698]", "Ubiquinone biosynthesis protein COQ9 [IPR012762]", "Ubiquitin binding protein, Hrs/VPS27 [IPR017073]", "Ubiquitin carboxyl-terminal hydrolase 10 [IPR028767]", "Ubiquitin carboxyl-terminal hydrolase 14-like [IPR044635]", "Ubiquitin conjugation factor E4 [IPR045132]", "Ubiquitin fusion degradation protein Ufd1-like [IPR004854]", "Ubiquitin thioesterase OTUB1 [IPR030298]", "Ubiquitin thioesterase Otubain [IPR016615]", "Ubiquitin-activating enzyme E1 [IPR018075]", "Ubiquitin-like modifier Hub1/Ubl5 [IPR039732]", "Ubiquitin-protein ligase E3A [IPR017134]", "Ubiquitin-protein ligase E3B/C [IPR044611]", "Ubiquitin/SUMO-activating enzyme E1 [IPR000011]", "Ubiquitinyl hydrolase [IPR016652]", "Ubiquitinyl hydrolase, UCH37 type [IPR017390]", "Uncharacterised conserved protein UCP013899, metal binding [IPR016617]", "Uncharacterised protein family UPF0449 [IPR028227]", "Uncharacterised protein family, TMEM59 [IPR022065]", "Uncharacterized protein C17orf80 [IPR037694]", "Uncharacterized protein C19orf47-like [IPR039161]", "Uncharacterized protein KIAA2013-like [IPR018795]", "Unconventional myosin-XVIIIa [IPR031244]", "Ureohydrolase [IPR006035]", "Uridine kinase-like [IPR000764]", "Uridine-cytidine kinase 2 [IPR029925]", "Uroporphyrinogen decarboxylase HemE [IPR006361]", "V-type ATPase, V0 complex, 116kDa subunit family [IPR002490]", "V-type ATP synthase catalytic alpha chain [IPR022878]", "V-type ATP synthase regulatory subunit B/beta [IPR022879]", "V-type ATPase subunit E [IPR002842]", "V0 complex accessory subunit Ac45 [IPR008388]", "VPRBP/DCAF1 family [IPR033270]", "Vacuolar protein sorting protein 26 related [IPR028934]", "Vacuolar protein sorting-associated protein 13 [IPR026847]", "Vacuolar protein sorting-associated protein 29 [IPR028661]", "Vacuolar protein sorting-associated protein 33 [IPR027121]", "Vacuolar protein sorting-associated protein 35 [IPR005378]", "Vacuolar protein sorting-associated protein 4 [IPR031255]", "Vacuolar protein sorting-associated protein 51 [IPR014812]", "Vacuolar protein sorting-associated protein 53 [IPR039766]", "Vacuolar protein sorting-associated protein 9-like [IPR045046]", "Vacuolar protein sorting-associated protein Ist1 [IPR005061]", "Vacuolar protein sorting-associated protein Vta1-like [IPR044538]", "Vacuolar protein-sorting protein Bro1-like [IPR045251]", "Valine-tRNA ligase [IPR002303]", "Vam6/VPS39/TRAP1 family [IPR032914]", "Vasodilator-stimulated phosphoprotein [IPR034367]", "Vasodilator-stimulated phosphoprotein/ENA/VASP-like [IPR017354]", "Vesicle transport protein, Got1/SFT2-like [IPR007305]", "Vesicle transport protein, Use1 [IPR019150]", "Vesicle-associated membrane-protein-associated protein [IPR016763]", "Vesicle-fusing ATPase [IPR039812]", "Vesicle-trafficking protein Sec22 [IPR044565]", "Vezatin [IPR026858]", "Villin/Gelsolin [IPR007122]", "Vimentin [IPR027699]", "Vinculin [IPR017997]", "Vinculin/alpha-catenin [IPR006077]", "Vitamin K epoxide reductase complex subunit 1 [IPR042406]", "Vitamin K-dependent gamma-carboxylase [IPR007782]", "Voltage-dependent anion-selective channel protein 1 [IPR030270]", "Voltage-dependent anion-selective channel protein 2 [IPR030277]", "Voltage-dependent anion-selective channel protein 3 [IPR030271]", "Vps52 [IPR007258]", "WASH complex subunit 7 [IPR027307]", "WD repeat BOP1/Erb1 [IPR028598]", "WD repeat HIR1 [IPR031120]", "WD repeat Prp46/PLRG1-like [IPR045241]", "WD repeat WDR12/Ytm1 [IPR028599]", "WD repeat-containing protein 11 [IPR039694]", "WD repeat-containing protein 41 [IPR040102]", "WD repeat-containing protein 73 [IPR042795]", "WD repeat-containing protein 91 [IPR039724]", "WD repeat-containing protein DCAF7-like [IPR045159]", "WD repeat-containing protein WDR18/Ipi3/RID3 [IPR045227]", "WD repeat-containing protein WDR46/Utp7 [IPR040315]", "WD40 repeat-containing protein SMU1 [IPR045184]", "WDR74/Nsa1 [IPR037379]", "WW domain binding protein 11 [IPR019007]", "WW domain-binding protein 2 [IPR033598]", "WW domain-binding protein 2-like [IPR044852]", "Wings apart-like protein [IPR039874]", "Wolframin [IPR026208]", "Wolframin family [IPR026209]", "XMAP215 family [IPR045110]", "XPG/Rad2 endonuclease [IPR006084]", "YAP-binding/ALF4/Glomulin [IPR013877]", "YEATS [IPR005033]", "YLP motif-containing protein 1 [IPR026314]", "YTH domain containing protein [IPR045168]", "YgfZ/GcvT [IPR045179]", "Yif1 family [IPR005578]", "YjeF N-terminal domain-containing protein NAXE-like [IPR032976]", "YjgF/YER057c/UK114 family [IPR006175]", "ZPR1 family [IPR040141]", "Zinc finger CCCH domain-containing protein A/B [IPR039691]", "Zinc finger CCHC domain-containing protein 3 [IPR042509]", "Zinc finger CCHC-type and RNA-binding motif-containing protein 1 [IPR044598]", "Zinc finger FYVE domain containing protein, SARA/endofin [IPR035438]", "Zinc finger FYVE domain-containing protein, endofin [IPR017165]", "Zinc finger Ran-binding domain-containing protein 2 [IPR017337]", "Zinc finger ZZ-type and EF-hand domain-containing protein 1 [IPR040099]", "Zinc finger protein 532-like [IPR045914]", "Zinc finger protein 622/Rei1/Reh1 [IPR040025]", "Zinc finger protein 638 [IPR033096]", "Zinc transporter Msc2-like [IPR045316]", "cAMP response element binding (CREB) protein [IPR001630]", "cAMP-dependent protein kinase catalytic subunit [IPR044109]", "cAMP-dependent protein kinase regulatory subunit [IPR012198]", "cAMP-responsive element-binding protein 1 [IPR029802]", "dCTP pyrophosphatase 1 [IPR025984]", "dTDP-4-dehydrorhamnose reductase family [IPR005913]", "hnRNP A2/B1 [IPR034489]", "mRNA 3'-end-processing protein Rna14-like [IPR045243]", "mRNA export factor Gle2/RAE1 [IPR037631]", "mRNA-decapping enzyme subunit 1 [IPR010334]", "p53 tumour suppressor family [IPR002117]", "rRNA biogenesis protein Rrp5 [IPR045209]", "tRNA (C5-cytosine) methyltransferase, NCL1 [IPR023270]", "tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 [IPR017423]", "tRNA (guanine-N1-)-methyltransferase, eukaryotic [IPR007356]", "tRNA (uracil(54)-C(5))-methyltransferase, eukaryotic type [IPR045850]", "tRNA N6-adenosine threonylcarbamoyltransferase Kae1, archaea and eukaryote [IPR034680]", "tRNA guanosine-2'-O-methyltransferase, TRM11 [IPR016691]", "tRNA isopentenyltransferase, eukaryotes [IPR030666]", "tRNA methyltransferase 10 homologue C [IPR025812]", "tRNA methyltransferase, Trm1 [IPR002905]", "tRNA modification GTPase MnmE [IPR004520]", "tRNA pseudouridine synthase B family [IPR004802]", "tRNA pseudouridine synthase II, TruB [IPR014780]", "tRNA-specific 2-thiouridylase [IPR004506]", "tRNAHis guanylyltransferase Thg1 [IPR007537]"], "available_proteins": ["AAAS", "AACS", "AAR2", "AARS", "AARS2", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCE1", "ABHD12", "ABHD6", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACADM", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL6", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ADA", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFG3L2", "AGL", "AGPS", "AHCY", "AHCYL1", "AHSA1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKT1", "AKT1S1", "ALCAM", "ALDH18A1", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG2", "ALKBH5", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANKLE2", "ANO6", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APBB1", "APC", "APEX1", "API5", "APLP2", "APOL2", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFIP1", "ARFIP2", "ARG2", "ARHGDIA", "ARID1A", "ARIH1", "ARL1", "ARL10", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARL8B", "ARMC1", "ARMC6", "ARMC8", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARVCF", "ASAH1", "ASNA1", "ASNS", "ASPH", "ATAD2", "ATAD3A", "ATAD3B", "ATG4B", "ATG9A", "ATIC", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPAF2", "ATPIF1", "ATXN2L", "AURKB", "B4GAT1", "BABAM1", "BABAM2", "BAG4", "BAG5", "BAIAP2", "BANF1", "BAP18", "BASP1", "BAX", "BAZ2A", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCL2L13", "BCLAF1", "BDH2", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD7", "BRD8", "BRI3BP", "BRIX1", "BROX", "BSG", "BTF3", "BUB1B", "BUD23", "BUD31", "BYSL", "C12orf43", "C12orf73", "C14orf2", "C16orf58", "C17orf80", "C19orf25", "C19orf47", "C19orf70", "C1D", "C1QBP", "C1orf123", "C1orf35", "C2CD2L", "C2CD5", "C3orf58", "C5orf15", "C5orf24", "C5orf51", "C8orf59", "CAB39", "CAD", "CALD1", "CALR", "CALU", "CAMLG", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN7", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CAST", "CBL", "CBR1", "CBX2", "CBX3", "CCAR1", "CCAR2", "CCDC124", "CCDC127", "CCDC134", "CCDC138", "CCDC22", "CCDC47", "CCDC58", "CCDC6", "CCDC8", "CCDC86", "CCDC93", "CCDC97", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC20", "CDC37", "CDC40", "CDC42", "CDC45", "CDC6", "CDC73", "CDCA2", "CDCA5", "CDCA7L", "CDCA8", "CDH2", "CDK5RAP3", "CDK6", "CDKAL1", "CDR2L", "CDS2", "CEBPZ", "CELF2", "CENPB", "CEP135", "CEP170", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1L", "CHD8", "CHERP", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHST14", "CIAPIN1", "CIP2A", "CISD1", "CISD2", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSTN3", "CLTA", "CLTC", "CLU", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT10", "CNOT11", "CNOT2", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COG3", "COG7", "COIL", "COLGALT1", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "COQ8B", "COQ9", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPSF2", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CREB1", "CREG1", "CRNKL1", "CRTAP", "CRYZL1", "CS", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTH", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CUTA", "CWC15", "CWF19L1", "CXorf57", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAXX", "DBN1", "DBNL", "DCAF1", "DCAF7", "DCAKD", "DCD", "DCP1A", "DCPS", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDOST", "DDRGK1", "DDT", "DDX54", "DECR1", "DEK", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS4", "DHRS7", "DHRS7B", "DHTKD1", "DHX29", "DIABLO", "DIAPH1", "DIAPH3", "DIDO1", "DIEXF", "DIMT1", "DKC1", "DLAT", "DLD", "DLG1", "DLST", "DMAP1", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJC10", "DNAJC13", "DNAJC2", "DNAJC8", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLPP1", "DPH2", "DPH5", "DPM1", "DPP3", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUT", "DVL2", "DYM", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC4", "EEF1A2", "EEF1E1", "EEF1G", "EFHD1", "EGFR", "EHD1", "EHD4", "EHHADH", "EHMT2", "EI24", "EIF2A", "EIF2B1", "EIF2B2", "EIF2B4", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMD", "EMG1", "ENDOD1", "ENO1", "ENO2", "ENPP1", "ENSA", "EPB41", "EPB41L2", "EPB41L3", "EPDR1", "EPHA7", "EPHX1", "EPPK1", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERGIC1", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ESD", "ESF1", "ESPL1", "ESS2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC9", "EYA4", "EZH2", "EZR", "F11R", "FABP5", "FADS2", "FAH", "FAM114A2", "FAM120A", "FAM120B", "FAM129B", "FAM136A", "FAM162A", "FAM177A1", "FAM210B", "FAM213A", "FAM3C", "FAM49B", "FAM8A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP2", "FARSA", "FARSB", "FAU", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNBP1L", "FSCN1", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GALK1", "GALM", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GCAT", "GCFC2", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN4", "GET4", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GGPS1", "GHDC", "GHITM", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLUD1", "GM2A", "GMFB", "GNA13", "GNAI2", "GNAI3", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLPH3L", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPAM", "GPD2", "GPHN", "GPI", "GPKOW", "GPR107", "GPR108", "GPR89B", "GPRASP2", "GPS1", "GRIPAP1", "GRPEL1", "GRSF1", "GSK3B", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS4", "HAUS5", "HAUS6", "HAX1", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDHD2", "HDHD3", "HDHD5", "HEATR1", "HEBP1", "HECTD1", "HECTD3", "HELZ", "HEXA", "HEXB", "HEXIM1", "HGH1", "HGS", "HIBADH", "HIBCH", "HINT2", "HIRA", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLCS", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN3", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPC", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HP1BP3", "HPRT1", "HPS3", "HPS6", "HPSE", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTRA2", "HTT", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IFT52", "IGBP1", "IGF2BP2", "IGHMBP2", "IK", "IKBIP", "ILF3", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPAD1", "IMPDH2", "INA", "INCENP", "INF2", "INTS1", "INTS12", "INTS13", "INTS14", "INTS3", "INTS7", "INTS9", "IPO4", "IPO5", "IRS4", "ISCU", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITM2B", "ITM2C", "ITPA", "ITPRIP", "IVD", "JAGN1", "JPT2", "JUP", "KARS", "KDELR1", "KDELR3", "KDM1A", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHDRBS3", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1468", "KIAA2013", "KIF14", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF5B", "KIFBP", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAMTOR3", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDAH", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3", "LGMN", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMF2", "LNPEP", "LONP1", "LONP2", "LRPAP1", "LRPPRC", "LRRC47", "LRRFIP2", "LSG1", "LSM12", "LSM2", "LSM3", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L", "LUC7L2", "LUC7L3", "LUZP1", "LYAR", "LZIC", "LZTFL1", "LZTS2", "MACF1", "MAD2L1", "MAGED1", "MAGED2", "MAGT1", "MAK16", "MAN1A1", "MAN1A2", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP4", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCKS", "MARCKSL1", "MARK3", "MARS", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MEAF6", "MECP2", "MED14", "MED16", "MED17", "MED21", "MED23", "MED24", "MED25", "MED4", "MEN1", "MEPCE", "MESD", "METAP1", "METTL15", "MFAP1", "MFF", "MFN1", "MFSD10", "MFSD3", "MFSD5", "MGEA5", "MGST1", "MGST2", "MGST3", "MICU1", "MICU2", "MIF", "MINDY3", "MINPP1", "MIOS", "MIPEP", "MKRN2", "MLEC", "MMAB", "MMS19", "MMS22L", "MOB4", "MOGS", "MON2", "MORF4L1", "MORF4L2", "MOV10", "MPC2", "MPDZ", "MPG", "MPHOSPH10", "MPI", "MPST", "MPV17L2", "MRE11", "MRGBP", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL40", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL55", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSN", "MTA1", "MTA2", "MTAP", "MTBP", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTM1", "MTMR2", "MTMR6", "MTOR", "MTR", "MTX1", "MTX2", "MTX3", "MXRA7", "MYBBP1A", "MYCBP", "MYDGF", "MYEF2", "MYG1", "MYO18A", "NAA10", "NAA15", "NAA40", "NADK2", "NAE1", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NAT10", "NAXE", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCBP1", "NCBP3", "NCDN", "NCK1", "NCK2", "NCKAP1", "NCKIPSD", "NCLN", "NCSTN", "ND1", "NDC1", "NDRG3", "NDUFA13", "NDUFA4", "NDUFAF3", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB4", "NDUFB5", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4L", "NEFL", "NEFM", "NELFB", "NELFCD", "NELFE", "NES", "NEU1", "NF2", "NFRKB", "NFS1", "NHP2", "NIP7", "NIPBL", "NLN", "NMD3", "NME1", "NME2", "NME3", "NME7", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL9", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NRP1", "NSA2", "NSF", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDT1", "NUDT21", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUTF2", "NXF1", "OAT", "OCIAD1", "OCLN", "ODR4", "OGDH", "OGFOD3", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "ORC5", "OS9", "OSBP", "OSBPL11", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OXA1L", "OXSR1", "P3H1", "P3H3", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAIP2", "PAK2", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PAWR", "PAXBP1", "PBDC1", "PBRM1", "PC", "PCBD1", "PCDH19", "PCID2", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6IP", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDP1", "PDS5A", "PDS5B", "PDSS2", "PDXK", "PEBP1", "PECR", "PES1", "PEX14", "PEX16", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM3", "PGP", "PHAX", "PHB", "PHB2", "PHF10", "PHF5A", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PI4KB", "PIBF1", "PICALM", "PIGK", "PIGL", "PIGS", "PIGT", "PIK3C2A", "PIK3R4", "PIN4", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNB", "PKM", "PKMYT1", "PKP2", "PLA2G15", "PLBD2", "PLCG1", "PLEC", "PLIN3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPO", "PNPT1", "POFUT1", "POFUT2", "POLA1", "POLA2", "POLD1", "POLD2", "POLE", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3F", "POLRMT", "POMGNT2", "PON2", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPHLN1", "PPIE", "PPIH", "PPIL1", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1R12A", "PPP1R9B", "PPP2R1A", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4R2", "PPP5C", "PPP6R3", "PPT1", "PPT2", "PRAF2", "PRC1", "PRCP", "PRDX2", "PRDX5", "PRDX6", "PREB", "PRELID1", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF40A", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PTBP1", "PTBP2", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTRH2", "PUDP", "PUF60", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "PYM1", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABEP1", "RABGAP1", "RABGGTA", "RABL6", "RAC1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBFOX2", "RBM10", "RBM17", "RBM22", "RBM26", "RBM27", "RBM39", "RBM5", "RBM6", "RBM8A", "RBPJ", "RCC2", "RCL1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "RECQL5", "REEP3", "REEP4", "REEP5", "REL", "REPS1", "RER1", "REXO2", "REXO4", "RFC1", "RFT1", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RICTOR", "RIDA", "RIF1", "RINT1", "RIOX1", "RIOX2", "RNASEH2A", "RNASET2", "RNF14", "RNF20", "RNF219", "RNF40", "RNPEP", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS19BP1", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RTCA", "RTCB", "RTFDC1", "RTN4IP1", "RTRAF", "RUVBL1", "RUVBL2", "RXRB", "S100A10", "S100A11", "S100A13", "SAE1", "SAFB", "SAFB2", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARS", "SARS2", "SART1", "SATB2", "SBDS", "SBNO1", "SCAF1", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCD", "SCFD1", "SCO1", "SCO2", "SCPEP1", "SCRN1", "SDAD1", "SDCBP", "SDCCAG3", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT8", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A3", "SF3B1", "SF3B5", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHC1", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIKE1", "SIN3A", "SIN3B", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A40", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC30A7", "SLC35A4", "SLC35B2", "SLC35F2", "SLC3A2", "SLC4A7", "SLC5A6", "SLC6A15", "SLC7A1", "SLFN11", "SLK", "SLMAP", "SLTM", "SMARCA4", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMCHD1", "SMG8", "SMG9", "SMPD4", "SMU1", "SND1", "SNRPA1", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SPAG5", "SPAG9", "SPART", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPECC1L", "SPNS1", "SPOUT1", "SPPL2A", "SPR", "SPRYD7", "SPTBN1", "SPTBN2", "SQLE", "SRFBP1", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPRB", "SRRT", "SRSF10", "SRSF11", "SRSF6", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STARD3", "STAT1", "STIP1", "STMN1", "STOM", "STOML2", "STRBP", "STRIP1", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX3", "STX5", "STX6", "STX7", "STX8", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SURF4", "SURF6", "SV2A", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "TAB1", "TACO1", "TAF15", "TAF4", "TAF7", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARBP1", "TARS", "TARS2", "TARSL2", "TBCA", "TBCD", "TBCE", "TBL2", "TCEA1", "TCERG1", "TCF25", "TCOF1", "TCP1", "TECR", "TENM3", "TERF2IP", "TES", "TEX10", "TFB1M", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "TIGAR", "TIMELESS", "TIMM13", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TJP1", "TJP2", "TK1", "TM9SF2", "TM9SF3", "TM9SF4", "TMA16", "TMCO1", "TMED1", "TMED10", "TMED2", "TMED5", "TMED9", "TMEM109", "TMEM11", "TMEM126A", "TMEM14C", "TMEM160", "TMEM165", "TMEM167A", "TMEM177", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM30A", "TMEM33", "TMEM38B", "TMEM43", "TMEM59", "TMEM70", "TMEM97", "TMF1", "TMLHE", "TMOD1", "TMOD3", "TMX2", "TNKS1BP1", "TNPO1", "TOE1", "TOM1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOR1A", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TOX4", "TP53", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP2", "TPT1", "TPX2", "TRABD", "TRAM1", "TRAP1", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM28", "TRIP12", "TRIP13", "TRIT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSC2", "TSFM", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPO", "TSPYL1", "TSR1", "TSR2", "TST", "TSTA3", "TTC19", "TTC21B", "TTC26", "TTC27", "TTC37", "TTC38", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC16", "TXNDC17", "TXNDC9", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UACA", "UAP1", "UBA1", "UBA2", "UBA5", "UBA6", "UBAP2", "UBAP2L", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBL5", "UBN2", "UBQLN1", "UBR4", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "UMPS", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCC2", "UQCR10", 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b/interpro_homologous_superfamily/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:46d7bf63f03cb20916f2813dc6e57692c9314c9770ffee9bc7f34d3e807ad5df +size 104235 diff --git a/interpro_homologous_superfamily/df_merge.tsv b/interpro_homologous_superfamily/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..2ae0dfdc5ae9c2d4845e2b212a52528e38a12656 --- /dev/null +++ b/interpro_homologous_superfamily/df_merge.tsv @@ -0,0 +1,13 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Tetratricopeptide-like helical domain superfamily [IPR011990] 38 90 3.103522186805788 0.0019123189589222 22.856796116504853 85.5631067961165 0.5676132842696584 0.6143258973719493 7.683128498309678 5.891280215778877 0.9202004538980384 0.371378017802006 0.3531050613285967 0.5664012088569712 0.4948207332297397 0.1263375409848138 9.770655310214495e-06 +Mitochondrial carrier domain superfamily [IPR023395] 4 21 2.2912139971222376 0.0219510398088893 9.148058252427184 20.71359223300971 2.0411027534642088 0.1411881998864352 5.368907349966936 1.8276489510009888 1.309103123363054 0.2428184236965967 0.0111023154777706 0.1675604235637086 0.0513963234576887 0.064307133891248 0.0359117122080593 +Nucleophile aminohydrolases, N-terminal [IPR029055] 6 17 2.2674476658157667 0.0233628924729292 6.097087378640777 17.820388349514563 1.118176330768516 0.343571999079937 2.960138290874742 0.7151426259133536 1.128434210928413 0.3328142150103464 0.2656377065204329 0.1135912525516411 0.2147385524083838 0.0220300654060922 0.0001398373652982 +Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097] 2 6 2.1463745148665527 0.0318431109160448 2.111650485436894 5.548543689320389 1.4203309343737989 0.1835434124596617 1.027373025804284 0.6683357213562342 0.9844971330203006 0.2264468231852968 0.0001431820583304 0.0007972103198291 0.0031504918831051 0.0010713621736615 0.0077568745967145 +Peptidase M4/M1, CTD superfamily [IPR027268] 2 6 2.1463745148665527 0.0318431109160448 2.111650485436894 5.548543689320389 1.4203309343737989 0.1835434124596617 1.027373025804284 0.6683357213562342 0.9844971330203006 0.2264468231852968 0.0001431820583304 0.0007972103198291 0.0031504918831051 0.0010713621736615 0.0077568745967145 +LEM/LEM-like domain superfamily [IPR011015] 1 6 2.138766040286787 0.0324546210896599 2.237864077669903 5.759708737864078 0.8787481060627674 0.3228260833428172 1.2758866328838632 0.4653299410110203 1.033781091163317 0.2887768895441466 0.0713572297582373 1.0 0.0563150378970086 0.0082857576662697 0.0312108672695238 +P-type ATPase, transmembrane domain superfamily [IPR023298] 3 6 2.0877925802438866 0.0368165491671925 2.941747572815534 6.145631067961165 0.9567723497044874 0.2732808833570771 1.8358630293390923 1.459204245106796 1.2102525517005158 0.2943240638910574 0.2472517806302485 1.0 0.1993869387044997 0.1067922158236129 0.3097803043008575 +P-type ATPase, cytoplasmic domain N [IPR023299] 3 6 2.0877925802438866 0.0368165491671925 2.941747572815534 6.145631067961165 0.9567723497044874 0.2732808833570771 1.8358630293390923 1.459204245106796 1.2102525517005158 0.2943240638910574 0.237888308904226 1.0 0.191600110602388 0.0990342687178565 0.2914565107291916 +P-type ATPase, A domain superfamily [IPR008250] 3 6 2.0877925802438866 0.0368165491671925 2.941747572815534 6.145631067961165 0.9567723497044874 0.2732808833570771 1.8358630293390923 1.459204245106796 1.2102525517005158 0.2943240638910574 0.237888308904226 1.0 0.191600110602388 0.0990342687178565 0.2914565107291916 +Glutathione S-transferase, C-terminal domain superfamily [IPR036282] 2 18 2.062876897737798 0.0391243255783511 4.434466019417476 16.66747572815534 0.2357810231502951 0.5538564173973619 3.0446637157573253 1.3736813401106382 0.9202997959616273 0.3110539503026115 0.0026629920200185 0.0053672672920639 0.0013262573806951 0.0175758241055335 0.09905667817091 +Cyclic nucleotide-binding-like [IPR018490] 2 5 2.0313411315621 0.0422204016506215 1.4902912621359223 4.660194174757281 -0.0126471736913758 0.4102849468515657 0.986512397936728 0.870814795980239 1.213781652340298 0.307139032821674 1.0 1.0 1.0 1.0 0.010684483318579 +RmlC-like jelly roll fold [IPR014710] 5 9 2.0140493688783163 0.044004350504633 2.6674757281553396 8.854368932038835 -0.0937515355609403 0.4128896377036541 1.427405289699237 1.237816484902717 1.1647229558969296 0.2931874986313249 1.0 1.0 1.0 0.0840389641709933 0.0002808101441202 diff --git a/interpro_homologous_superfamily/metrics.json b/interpro_homologous_superfamily/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..79636954dee280086896e15ce3f1e15c7ec9a761 --- /dev/null +++ b/interpro_homologous_superfamily/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3381, + "annotations_size": 1018, + "title": "Average number of proteins per term", + "value": 4.8870333988212185 +} \ No newline at end of file diff --git a/interpro_homologous_superfamily/paths.json b/interpro_homologous_superfamily/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..157abb12e36672ece084debc4171bb0015abe482 --- /dev/null +++ b/interpro_homologous_superfamily/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_homologous_superfamily/fragment/C317/C317_val_log2fc"} \ No newline at end of file diff --git a/interpro_homologous_superfamily/result.tsv b/interpro_homologous_superfamily/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..3875554c70b13adab94d1c70050bedf340af7fa6 --- /dev/null +++ b/interpro_homologous_superfamily/result.tsv @@ -0,0 +1,117 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Tetratricopeptide-like helical domain superfamily [IPR011990] 0.4594223744068378 3.103522186805788 0.0019123189589222 0.8575272422479966 0.5433324965121794 90 P13674,O75153,Q9H0B6,Q7L5D6,Q9Y5A7,P50542,O00170,Q9UBV2,Q96EK5,Q8IVL6,P42704,Q5VZ89,Q96TC7,Q9UJX3,Q32P28,Q96DB5,Q96EY7,O15294,P61201,O15460,O43242,Q9BXJ9,Q9Y262,Q15006,Q6PGP7,Q7Z4L5,Q6P3X3,Q6DKK2,O00231,Q92791,O95801,A0AVF1,O75718,Q96BR5,Q02790,Q9UJX4,Q9BQ70,Q6P2P2 38 +Mitochondrial carrier domain superfamily [IPR023395] 0.5792617613881876 2.2912139971222376 0.0219510398088893 0.999999999846154 0.6449652367138905 21 Q9UBX3,O43772,Q9H2D1,Q70HW3 4 +Nucleophile aminohydrolases, N-terminal [IPR029055] 0.6270379401856152 2.2674476658157667 0.0233628924729292 0.9999999999646476 0.6449652367138905 17 P28072,P28070,P28074,P20618,Q06203,P49721 6 +Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097] 0.8007907825564105 2.1463745148665527 0.0318431109160448 0.9999999999999952 0.6449652367138905 6 P55786,Q9NZ08 2 +Peptidase M4/M1, CTD superfamily [IPR027268] 0.8007907825564105 2.1463745148665527 0.0318431109160448 0.9999999999999952 0.6449652367138905 6 P55786,Q9NZ08 2 +LEM/LEM-like domain superfamily [IPR011015] 0.7990493285094713 2.138766040286787 0.0324546210896599 0.9999999999999974 0.6449652367138905 6 Q86XL3 1 +NAP-like superfamily [IPR037231] 0.9029238200973716 2.128446346774769 0.0333000939386578 0.9999999999999988 0.6449652367138905 4 Q99733,Q01105 2 +P-type ATPase, transmembrane domain superfamily [IPR023298] 0.7874198459158005 2.0877925802438866 0.0368165491671925 1.0 0.6449652367138905 6 P16615,Q9HD20,P05023 3 +P-type ATPase, cytoplasmic domain N [IPR023299] 0.7874198459158005 2.0877925802438866 0.0368165491671925 1.0 0.6449652367138905 6 P16615,Q9HD20,P05023 3 +P-type ATPase, A domain superfamily [IPR008250] 0.7874198459158005 2.0877925802438866 0.0368165491671925 1.0 0.6449652367138905 6 P16615,Q9HD20,P05023 3 +Glutathione S-transferase, C-terminal domain superfamily [IPR036282] 0.580273500558078 2.062876897737798 0.0391243255783511 1.0 0.6449652367138905 18 Q13505,P78417 2 +Cyclic nucleotide-binding-like [IPR018490] 0.8234345239911576 2.0313411315620997 0.0422204016506215 1.0 0.6449652367138905 5 Q8IY17,Q9Y4G8 2 +RmlC-like jelly roll fold [IPR014710] 0.71180504576283 2.0140493688783163 0.044004350504633 1.0 0.6449652367138905 9 Q9Y4G8,Q6P4Q7,O00625,P38435,Q8IY17 5 +K Homology domain, type 1 superfamily [IPR036612] 0.5269243381190284 1.9003950443300512 0.057381296773318 1.0 0.6449652367138905 28 O75525,Q92945,Q9Y6M1,Q9UNW9,Q9Y2W6,Q07666,P61978,Q13868,Q96PU8,P51116,Q96I24,Q96AE4 12 +Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400] 0.7154741516057801 1.8455438658770331 0.0649584635865694 1.0 0.6506565361371761 7 Q9UMX5,O43169,Q8WUJ1 3 +DHS-like NAD/FAD-binding domain superfamily [IPR029035] 0.7058180331016621 1.800414913950387 0.0717951476423075 1.0 0.6607205026141905 7 Q13423 1 +Porin domain superfamily [IPR023614] 0.8192732781313572 1.7929083967093338 0.0729875725068085 1.0 0.6607205026141905 4 P21796 1 +Acyl-CoA N-acyltransferase [IPR016181] 0.6415001539921554 1.66090108016198 0.0967333153013365 1.0 0.6626766280008226 9 O60502 1 +Tim10-like domain superfamily [IPR035427] 0.7799822327509576 1.6319953921049506 0.1026804568987871 1.0 0.6626766280008226 4 Q9Y5J7,Q9Y5J9,O60220 3 +Proteasome activator PA28, N-terminal domain superfamily [IPR036996] 0.8626406157489638 1.599037263341476 0.1098123230513268 1.0 0.6626766280008226 3 P61289,Q06323 2 +Proteasome activator superfamily [IPR036252] 0.8626406157489638 1.599037263341476 0.1098123230513268 1.0 0.6626766280008226 3 P61289,Q06323 2 +Proteasome activator PA28, C-terminal domain superfamily [IPR036997] 0.8626406157489638 1.599037263341476 0.1098123230513268 1.0 0.6626766280008226 3 P61289,Q06323 2 +Ricin B-like lectins [IPR035992] 0.7693218833283939 1.588033563605229 0.1122787497249429 1.0 0.6649913812608067 4 Q9UBG0,Q10471,Q10472 3 +PDZ superfamily [IPR036034] 0.4847192261171515 1.5702452274960106 0.1163580712942939 1.0 0.6655485000119186 29 O43464,Q96L92,Q96RT1,Q12959,P57105,Q9UDY2,Q9Y4G8,Q9NZW5,Q6ZWJ1,O14936,O14641,Q00013,Q8N3R9,P55196,Q9HD26,Q14168 16 +Six-hairpin glycosidase-like superfamily [IPR012341] 0.7148717617828094 1.566716119516267 0.1171810612651595 1.0 0.6664263707705724 5 P33908 1 +L27 domain superfamily [IPR036892] 0.6340649487607063 1.5364494389211514 0.1244281893236567 1.0 0.6747984029617937 8 Q12959,Q9NZW5,O14936,Q8N3R9,Q14168 5 +Haem oxygenase-like, multi-helical [IPR016084] 0.979875702870672 1.526265966042433 0.1269436409309055 1.0 0.6747984029617937 2 P30519 1 +EF-hand domain pair [IPR011992] 0.4492960730284482 1.520127418632639 0.128478954706525 1.0 0.6747984029617937 57 P35609,Q13813,Q96AY3,O95302,P0DP25,Q8IYU8,P80303,Q96D71,Q9Y680,P43304,P12814,Q14257,Q9NWM8,O43852,Q9H8M7,P41208,Q9BPX6 17 +Cytochrome P450 superfamily [IPR036396] 0.9668540988458127 1.4752246949561592 0.1401521443249371 1.0 0.6929634519765356 2 Q16850 1 +SNARE [IPR010989] 0.6399352935355097 1.4187390947907077 0.1559750949219069 1.0 0.7128004566143697 6 O43752,Q13277 2 +Neurolysin/Thimet oligopeptidase, domain 2 [IPR024077] 0.8132826930791204 1.4054367519629034 0.1598914445259014 1.0 0.7139012742428406 3 P52888 1 +Myosin S1 fragment, N-terminal [IPR008989] 0.7234150441231465 1.3975866959798282 0.1622372157553167 1.0 0.7180760245170105 4 P35579,P35580 2 +Class II aldolase/adducin N-terminal domain superfamily [IPR036409] 0.7898164594434645 1.3131758907848414 0.1891236859574527 1.0 0.7587748929222109 3 Q9UEY8,P35611 2 +DCN1-like, PONY binding domain [IPR042460] 0.7832355418367575 1.287309501660783 0.1979864330638243 1.0 0.767440628695229 3 Q92564 1 +Seven-hairpin glycosidases [IPR036026] 0.9121041728322 1.2611289750727577 0.2072623827693578 1.0 0.7724403894118893 2 P33908 1 +Golgi phosphoprotein 3-like domain superfamily [IPR038261] 0.910032554010063 1.253063221984021 0.2101826992800524 1.0 0.7724403894118893 2 Q9H4A5 1 +Metallopeptidase, catalytic domain superfamily [IPR024079] 0.5971693827426681 1.2189663317334067 0.2228569715009118 1.0 0.7910082783270076 6 Q9BYT8,P52888 2 +GOLD domain superfamily [IPR036598] 0.6788029900297957 1.21156057463374 0.225680633972076 1.0 0.7926156155156143 4 Q9Y3A6,Q15363 2 +Moesin tail domain superfamily [IPR008954] 0.6758933909543849 1.1994282806875558 0.2303614564510954 1.0 0.7926156155156143 4 P15311 1 +FAD-binding, type PCMH, subdomain 2 [IPR016169] 0.8913879846108332 1.1806657745078624 0.2377355229255431 1.0 0.7926156155156143 2 Q15392 1 +FAD-binding, type PCMH-like superfamily [IPR036318] 0.8913879846108332 1.1806657745078624 0.2377355229255431 1.0 0.7926156155156143 2 Q15392 1 +Bcl-2-like superfamily [IPR036834] 0.7557726465364101 1.179540084647218 0.2381831849518092 1.0 0.7926156155156143 3 Q07820,Q9BXK5 2 +Prefoldin [IPR009053] 0.6696774552678528 1.1735192360336415 0.2405876475386295 1.0 0.7926156155156143 4 O15212 1 +Zinc finger, RanBP2-type superfamily [IPR036443] 0.5448280541146457 1.1594264150712617 0.2462824147585074 1.0 0.7991994573402557 9 Q92804,P98175,Q01844,P35637 4 +HAD-like superfamily [IPR036412] 0.4218746142027781 1.1119000341215646 0.2661811340458389 1.0 0.8166366001622409 20 Q9BXW7,P05023,P16615,Q9BSH5,Q969T7,Q9HD20,P98194 7 +HAD superfamily [IPR023214] 0.4218746142027781 1.1119000341215646 0.2661811340458389 1.0 0.8166366001622409 20 Q9BXW7,P05023,P16615,Q9BSH5,Q969T7,Q9HD20,P98194 7 +PX domain superfamily [IPR036871] 0.4899935827503457 1.11023746900595 0.2668967107007891 1.0 0.8166366001622409 12 Q9Y5X3,O60749,Q9Y2I1,Q9UNH7 4 +Lamin tail domain superfamily [IPR036415] 0.7332741267021897 1.0916534412427914 0.2749854569273924 1.0 0.8166366001622409 3 P02545,Q03252 2 +Nucleotide-diphospho-sugar transferases [IPR029044] 0.4165936134996578 1.0709017994691563 0.2842135866837778 1.0 0.8166366001622409 20 Q9Y5P6,Q10472,Q68CQ7,P46976,Q10471,Q16739 6 +His-Me finger superfamily [IPR044925] 0.7264052777091938 1.0649328418320718 0.2869063218460543 1.0 0.8166366001622409 3 O94919 1 +DNA/RNA non-specific endonuclease superfamily [IPR044929] 0.7264052777091938 1.0649328418320718 0.2869063218460543 1.0 0.8166366001622409 3 O94919 1 +RmlC-like cupin domain superfamily [IPR011051] 0.6423393335595958 1.059855989949117 0.2892101201550532 1.0 0.8166366001622409 4 P38435,O00625 2 +AH/BAR domain superfamily [IPR027267] 0.4742335210711681 1.0465382265169223 0.2953126054927901 1.0 0.8166366001622409 13 Q9UQB8,P53365,Q9UNH7,Q9Y5X3 4 +Neurolysin/Thimet oligopeptidase, N-terminal [IPR024080] 0.8197691624741075 0.9079085268847426 0.3639265521767254 1.0 0.8910910675137447 2 P52888 1 +Metalloenzyme, LuxS/M16 peptidase-like [IPR011249] 0.5199713915367279 0.9076905673108124 0.3640417289656645 1.0 0.8910910675137447 7 P22695,Q5JRX3 2 +FAD/NAD(P)-binding domain superfamily [IPR036188] 0.3853302845030599 0.8290647810239525 0.4070677513413214 1.0 0.893392275269315 20 O95831,P43304,Q9UHG3 3 +Ubiquitin-like domain superfamily [IPR029071] 0.386361927627303 0.775687486827001 0.4379335299756188 1.0 0.8988232530547984 44 Q9Y4E8,P46379,O14641,Q9UMX0,Q96K76 5 +Rho GTPase activation protein [IPR008936] 0.4904188872991877 0.7670094941546265 0.4430758707149622 1.0 0.9032531623565048 7 Q14C86 1 +MoaB/Mog-like domain superfamily [IPR036425] 0.7801124593074897 0.7630110574076168 0.4454568014622508 1.0 0.9037409487617024 2 Q8NFF5 1 +Formin, FH2 domain superfamily [IPR042201] 0.5601417672370549 0.7260902364446745 0.4677834540505916 1.0 0.9282720394220318 4 Q9NSV4,Q27J81 2 +PABC (PABP) domain [IPR036053] 0.6238944791592429 0.6792032540843784 0.4970090857533287 1.0 0.9528347444385852 3 P11940 1 +Aldehyde dehydrogenase, C-terminal [IPR016163] 0.4384729088641488 0.6653177193822706 0.5058472995118422 1.0 0.953850986660168 10 P30837,P51648 2 +Aldehyde/histidinol dehydrogenase [IPR016161] 0.4384729088641488 0.6653177193822706 0.5058472995118422 1.0 0.953850986660168 10 P30837,P51648 2 +Aldehyde dehydrogenase, N-terminal [IPR016162] 0.4384729088641488 0.6653177193822706 0.5058472995118422 1.0 0.953850986660168 10 P30837,P51648 2 +Carboxypeptidase-like, regulatory domain superfamily [IPR008969] 0.7434152116010686 0.635102964000141 0.5253612640617435 1.0 0.9559870659664732 2 Q9P273 1 +UBA-like superfamily [IPR009060] 0.3584185542040774 0.5983865284439581 0.5495820525265929 1.0 0.9580043312877936 23 Q13501,Q04323,Q96RU2,Q9H1I8,Q9Y5A7,Q9UMX0 6 +Peptidase M41-like [IPR037219] 0.7312814442142681 0.5944646562431976 0.5522013748598091 1.0 0.9609247856534798 2 Q9Y4W6 1 +RGS domain superfamily [IPR036305] 0.7123409292690184 0.5329628773804467 0.5940592779818581 1.0 0.9889997943694367 2 P35579 1 +AF1104-like superfamily [IPR036075] 0.6954720331459054 0.4803939518380355 0.6309472941372665 1.0 1.0 2 Q9NVE7 1 +EXOC6/PINT-1/Sec15/Tip20, C-terminal, domain 2 [IPR042044] 0.6942882509618273 0.4767890885668331 0.6335123163814593 1.0 1.0 2 Q8TAG9 1 +EB1, C-terminal domain superfamily [IPR036133] 0.6827463746670656 0.4422541215343804 0.6583053259749272 1.0 1.0 2 Q15555 1 +START-like domain superfamily [IPR023393] 0.4761568395254897 0.4172743085287155 0.6764777781126985 1.0 1.0 4 Q14849 1 +Alpha-catenin/vinculin-like superfamily [IPR036723] 0.4749777909386896 0.4133359999003967 0.6793604577061996 1.0 1.0 4 Q9UBT7,P18206,Q9Y490 3 +Chaperone J-domain superfamily [IPR036869] 0.3452773400390929 0.3818595087153002 0.7025655757640901 1.0 1.0 17 O60884,Q13217,O75937,Q96KC8,Q99615,Q5F1R6,Q99543,Q8WXX5 8 +CRIB domain superfamily [IPR036936] 0.6540396567031714 0.3615437243535337 0.7176930249296656 1.0 1.0 2 Q13177 1 +Six-bladed beta-propeller, TolB-like [IPR011042] 0.3819006697542253 0.3191353732818169 0.7496238609936055 1.0 1.0 8 P13798 1 +14-3-3 domain superfamily [IPR036815] 0.3869629629629664 0.2995852009527869 0.7644935739050567 1.0 1.0 6 Q04917,P31946,P62258,P63104,P61981 5 +Kringle-like fold [IPR013806] 0.4966952434424564 0.2821699840787982 0.7778131727733697 1.0 1.0 3 Q9UBV2 1 +Fibronectin type II domain superfamily [IPR036943] 0.4966952434424564 0.2821699840787982 0.7778131727733697 1.0 1.0 3 Q9UBV2 1 +PH-like domain superfamily [IPR011993] 0.3193546860581626 0.2797490435829573 0.7796700485723833 1.0 1.0 59 O75116,P31749,P31751,O60333,P15311,P54105,O15020,P50570,Q9Y3P9,Q6IN85,Q86X55,Q01082 12 +Coatomer, gamma subunit, appendage domain superfamily [IPR037067] 0.6143829535365548 0.2637527111985298 0.7919704755239125 1.0 1.0 2 Q9UBF2 1 +GroES-like superfamily [IPR011032] 0.3452876139951582 0.2516714694695285 0.8012950113634123 1.0 1.0 11 Q8N4Q0 1 +TCP-1-like chaperonin intermediate domain superfamily [IPR027410] 0.3534214246528337 0.2298717233549226 0.8181914494730469 1.0 1.0 9 P49368 1 +GroEL-like apical domain superfamily [IPR027409] 0.3534214246528337 0.2298717233549226 0.8181914494730469 1.0 1.0 9 P49368 1 +GroEL-like equatorial domain superfamily [IPR027413] 0.3534214246528337 0.2298717233549226 0.8181914494730469 1.0 1.0 9 P49368 1 +Kinesin motor domain superfamily [IPR036961] 0.3056035298956729 0.2086359133940234 0.8347324726444918 1.0 1.0 25 Q7Z406,P33176,O60333,P35580,Q2M1P5,P35579,Q15058 7 +Choline/Carnitine o-acyltransferase, domain 2 [IPR042231] 0.5788694880142116 0.1912432352868524 0.8483350318161604 1.0 1.0 2 P23786 1 +Importin-alpha, importin-beta-binding domain superfamily [IPR036975] 0.3729265402843499 0.1896812876005828 0.8495588849304507 1.0 1.0 5 P52292,O00505,O60684,O00629 4 +Homeobox-like domain superfamily [IPR009057] 0.299202473738178 0.175795493879938 0.860454609870676 1.0 1.0 19 Q96G23 1 +Tubulin/FtsZ, GTPase domain superfamily [IPR036525] 0.3457576556263315 0.1734010068656431 0.8623362337297935 1.0 1.0 7 P68371,P07437,Q9BUF5,Q9BUK6 4 +MAN1, winged-helix domain [IPR041885] 0.5652559928973134 0.1674220315428149 0.8670379911628399 1.0 1.0 2 Q9Y2U8 1 +Rhomboid-like superfamily [IPR035952] 0.5634803196211962 0.1644787953091622 0.8693542382989867 1.0 1.0 2 Q9GZP9 1 +SMCs flexible hinge superfamily [IPR036277] 0.3609057649514972 0.1588144201925726 0.8738150873358237 1.0 1.0 5 Q9UQE7 1 +Tubulin, C-terminal [IPR023123] 0.3407407407407445 0.1526431394111993 0.8786797032852867 1.0 1.0 6 P68371,P07437,Q13509,Q13885,Q9BUF5 5 +Tubulin/FtsZ, C-terminal [IPR008280] 0.3407407407407445 0.1526431394111993 0.8786797032852867 1.0 1.0 6 P68371,P07437,Q13509,Q13885,Q9BUF5 5 +Tubulin/FtsZ-like, C-terminal domain [IPR037103] 0.3407407407407445 0.1526431394111993 0.8786797032852867 1.0 1.0 6 P68371,P07437,Q13509,Q13885,Q9BUF5 5 +Ubiquitin-conjugating enzyme/RWD-like [IPR016135] 0.3130755778903481 0.1438016826962564 0.8856570740883909 1.0 1.0 12 Q7Z7E8,Q9UBS8 2 +SGNH hydrolase superfamily [IPR036514] 0.5013317549570955 0.0845854335236755 0.932590979925964 1.0 1.0 2 P68402 1 +Paired amphipathic helix superfamily [IPR036600] 0.4664101805267909 0.0575543175853827 0.9541036386009228 1.0 1.0 2 O75182 1 +p53-like tetramerisation domain superfamily [IPR036674] 0.4598993785143614 0.0537071373586016 0.9571684962214496 1.0 1.0 2 Q13043 1 +Papain-like cysteine peptidase superfamily [IPR038765] 0.2761511963676761 0.0534364896738628 0.9573841321767036 1.0 1.0 23 Q9Y4E8,Q96K76 2 +Peptidase S8/S53 domain superfamily [IPR036852] 0.4483575022195996 0.0476950926615689 0.9619592451425748 1.0 1.0 2 P29144 1 +DNA mismatch repair protein MutS, N-terminal [IPR016151] 0.3472468916518666 0.0473956159747511 0.9621979230409584 1.0 1.0 3 P43246,P52701 2 +MutS, connector domain superfamily [IPR036678] 0.3472468916518666 0.0473956159747511 0.9621979230409584 1.0 1.0 3 P43246,P52701 2 +DNA mismatch repair protein MutS, core domain superfamily [IPR036187] 0.3472468916518666 0.0473956159747511 0.9621979230409584 1.0 1.0 3 P43246,P52701 2 +K homology domain-like, alpha/beta [IPR015946] 0.4178751109795888 0.036112626139428 0.9711925546920964 1.0 1.0 2 P23396 1 +K homology domain superfamily, prokaryotic type [IPR009019] 0.4178751109795888 0.036112626139428 0.9711925546920964 1.0 1.0 2 P23396 1 +S-adenosyl-L-methionine-dependent methyltransferase [IPR029063] 0.2826133966124171 0.0342785362284251 0.9726550404180878 1.0 1.0 30 Q96P11,A6NJ78,O60678,P21964,Q08J23,Q9BV86,Q86X55,Q6P2P2 8 +Translin, N-terminal [IPR016068] 0.3974548683042403 0.0311461354528491 0.9751529967291828 1.0 1.0 2 Q99598 1 +Translin, C-terminal [IPR016069] 0.3974548683042403 0.0311461354528491 0.9751529967291828 1.0 1.0 2 Q99598 1 +Translin superfamily [IPR036081] 0.3974548683042403 0.0311461354528491 0.9751529967291828 1.0 1.0 2 Q99598 1 +Cyclin-like superfamily [IPR036915] 0.2934557299378032 0.0278219074849185 0.9778041930782676 1.0 1.0 4 O95067,P20248,Q00403 3 +MRG, C-terminal domain superfamily [IPR038217] 0.3649008582420934 0.0264496899122258 0.9788986611769032 1.0 1.0 2 Q9UBU8 1 +Six-hairpin glycosidase superfamily [IPR008928] 0.3577981651376221 0.0258076519632964 0.9794107584988452 1.0 1.0 2 Q13724 1 +Sodium/potassium-transporting ATPase subunit beta superfamily [IPR038702] 0.2920982539212871 0.0232754764519879 0.9814305333700596 1.0 1.0 2 P05026 1 +NTF2-like domain superfamily [IPR032710] 0.2772802399198208 0.0084222954867009 0.993280059911296 1.0 1.0 7 Q13555,Q9UN86 2 diff --git a/interpro_homologous_superfamily/selections.json b/interpro_homologous_superfamily/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..3f013db92c8e56d55ea137f6d2baf6453d589b6d --- /dev/null +++ b/interpro_homologous_superfamily/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 domain superfamily [IPR036815]", "2Fe-2S ferredoxin-like superfamily [IPR036010]", "30s ribosomal protein S13, C-terminal [IPR027437]", "4'-phosphopantetheinyl transferase domain superfamily [IPR037143]", "5'-3' exonuclease, C-terminal domain superfamily [IPR036279]", "5-formyltetrahydrofolate cyclo-ligase-like domain superfamily [IPR024185]", "50S ribosomal protein L10, insertion domain superfamily [IPR043164]", "50S ribosomal protein L30e-like [IPR029064]", "6-phosphogluconate dehydrogenase, domain 2 [IPR013328]", "6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily [IPR008927]", "AAR2, C-terminal domain superfamily [IPR038514]", "AAR2, N-terminal domain superfamily [IPR038516]", "ABC transporter type 1, transmembrane domain superfamily [IPR036640]", "ACP-like superfamily [IPR036736]", "ADF-H/Gelsolin-like domain superfamily [IPR029006]", "ADP-ribosylation/Crystallin J1 superfamily [IPR036705]", "AF1104-like superfamily [IPR036075]", "AH/BAR domain superfamily [IPR027267]", "AICAR transformylase, duplicated domain superfamily [IPR024051]", "AICAR transformylase, insert domain superfamily [IPR024050]", "AMP-binding enzyme, C-terminal domain superfamily [IPR045851]", "AN1-like Zinc finger [IPR035896]", "ANL, N-terminal domain [IPR042099]", "ANTH domain superfamily [IPR014712]", "AP-2 complex subunit mu, C-terminal superfamily [IPR036168]", "APC, N-terminal coiled-coil domain superfamily [IPR036149]", "ARFGAP/RecO-like zinc finger [IPR037278]", "ARID DNA-binding domain superfamily [IPR036431]", "ATP synthase subunit alpha, N-terminal domain-like superfamily [IPR023366]", "ATP synthase, F0 complex, subunit A superfamily [IPR035908]", "ATP synthase, F0 complex, subunit D superfamily, mitochondrial [IPR036228]", "ATP synthase, F1 complex, gamma subunit superfamily [IPR035968]", "ATP synthase, alpha subunit, C-terminal domain superfamily [IPR038376]", "ATP-NAD kinase, PpnK-type, C-terminal [IPR017437]", "ATP-grasp fold, subdomain 1 [IPR013815]", "ATP12 orthogonal Bundle domain superfamily [IPR023335]", "ATP12, ATP synthase F1-assembly protein, N-terminal [IPR042272]", "ATP:guanido phosphotransferase, N-terminal domain superfamily [IPR036802]", "ATPase, F1/V1 complex, beta/alpha subunit, C-terminal [IPR024034]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily [IPR036121]", "ATPase, V1 complex, subunit H, C-terminal domain superfamily [IPR038497]", "ATPase, nucleotide binding domain [IPR043129]", "Acetylglutamate kinase-like superfamily [IPR036393]", "Aconitase, domain 2 [IPR015932]", "Aconitase, iron-sulfur domain [IPR036008]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 [IPR015931]", "Aconitase/3-isopropylmalate dehydratase, swivel [IPR015928]", "Actin-crosslinking [IPR008999]", "Actin-related protein 2/3 complex subunit 3 superfamily [IPR036753]", "Activator of Hsp90 ATPase, Aha1 [IPR036338]", "Acyl transferase domain superfamily [IPR001227]", "Acyl transferase/acyl hydrolase/lysophospholipase [IPR016035]", "Acyl-CoA N-acyltransferase [IPR016181]", "Acyl-CoA binding protein superfamily [IPR035984]", "Acyl-CoA dehydrogenase-like, C-terminal [IPR036250]", "Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily [IPR009100]", "Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily [IPR037069]", "Acyl-CoA thioesterase, double hotdog domain [IPR042171]", "Adaptor protein Cbl, N-terminal domain superfamily [IPR036537]", "Adenine nucleotide alpha hydrolase-like domains [IPR023382]", "Adenomatous polyposis coli protein [IPR026831]", "Adenosylhomocysteinase-like superfamily [IPR042172]", "Adenylate cyclase-associated CAP, C-terminal superfamily [IPR036223]", "Adenylate cyclase-associated CAP, N-terminal domain superfamily [IPR036222]", "Adenylate kinase, active site lid domain superfamily [IPR036193]", "Adenylosuccinate synthetase, domain 1 [IPR042109]", "Adenylosuccinate synthetase, domain 2 [IPR042110]", "Adenylosuccinate synthetase, domain 3 [IPR042111]", "Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily [IPR018162]", "Alba-like domain superfamily [IPR036882]", "Aldehyde dehydrogenase, C-terminal [IPR016163]", "Aldehyde dehydrogenase, N-terminal [IPR016162]", "Aldehyde/histidinol dehydrogenase [IPR016161]", "Aldolase-type TIM barrel [IPR013785]", "Alkaline-phosphatase-like, core domain superfamily [IPR017850]", "Allosteric substrate binding domain superfamily [IPR029009]", "Alpha-D-phosphohexomutase, C-terminal domain superfamily [IPR036900]", "Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III [IPR016055]", "Alpha-catenin/vinculin-like superfamily [IPR036723]", "Alpha-glycerophosphate oxidase, C-terminal domain superfamily [IPR038299]", "Alpha-helical ferredoxin [IPR009051]", "Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain superfamily [IPR036784]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily [IPR037151]", "Alpha-macroglobulin, receptor-binding domain superfamily [IPR036595]", "Alpha/Beta hydrolase fold [IPR029058]", "Alpha/beta knot methyltransferases [IPR029028]", "Amidase signature (AS) superfamily [IPR036928]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 [IPR020751]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding superfamily [IPR008925]", "Aminoacyl-tRNA synthetase, class Ia, anticodon-binding [IPR009080]", "Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097]", "Aminotransferase-like, PLP-dependent enzymes [IPR036038]", "Amyloidogenic glycoprotein, amyloid-beta peptide superfamily [IPR037071]", "Amyloidogenic glycoprotein, copper-binding domain superfamily [IPR036669]", "Amyloidogenic glycoprotein, heparin-binding domain superfamily [IPR036454]", "Ankyrin repeat-containing domain superfamily [IPR036770]", "Annexin superfamily [IPR037104]", "Anticodon-binding domain superfamily [IPR036621]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain superfamily [IPR036732]", "ApaG domain superfamily [IPR036767]", "Apyrase superfamily [IPR036258]", "ArfGAP domain superfamily [IPR038508]", "Arginyl tRNA synthetase N-terminal domain superfamily [IPR036695]", "Armadillo-like helical [IPR011989]", "Armadillo-type fold [IPR016024]", "Arp2/3 complex subunit 2/4 [IPR034666]", "Arrestin-like, C-terminal [IPR014752]", "Aspartate decarboxylase-like domain superfamily [IPR009010]", "Aspartate/ornithine carbamoyltransferase superfamily [IPR036901]", "Aspartic peptidase domain superfamily [IPR021109]", "Aspartyl/glutamyl-tRNA amidotransferase subunit B-like [IPR003789]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C-terminal, domain 2 [IPR023168]", "At2g17340, three-helix bundle domain [IPR035073]", "B30.2/SPRY domain superfamily [IPR043136]", "BAG domain superfamily [IPR036533]", "BEACH domain superfamily [IPR036372]", "BRCT domain superfamily [IPR036420]", "BRK domain superfamily [IPR037259]", "BRO1 domain superfamily [IPR038499]", "BSD domain superfamily [IPR035925]", "Band 7/SPFH domain superfamily [IPR036013]", "Barrier-to-autointegration factor, BAF superfamily [IPR036617]", "Bcl-2-like superfamily [IPR036834]", "Beta-Galactosidase/glucuronidase domain superfamily [IPR036156]", "Beta-catenin-interacting ICAT superfamily [IPR036911]", "Beta-grasp domain superfamily [IPR012675]", "Beta-hexosaminidase-like, domain 2 [IPR029018]", "Beta-lactamase/transpeptidase-like [IPR012338]", "Beta-trefoil domain superfamily [IPR036358]", "BolA-like superfamily [IPR036065]", "Branched-chain-amino-acid aminotransferase-like, C-terminal [IPR043132]", "Branched-chain-amino-acid aminotransferase-like, N-terminal [IPR043131]", "Bromo adjacent homology (BAH) domain superfamily [IPR043151]", "Bromodomain-like superfamily [IPR036427]", "C-type lectin fold [IPR016187]", "C-type lectin-like/link domain superfamily [IPR016186]", "C2 domain superfamily [IPR035892]", "CAP Gly-rich domain superfamily [IPR036859]", "CCR4-NOT complex subunit 2/3/5, N-terminal domain superfamily [IPR038635]", "CCR4-NOT subunit 1, TTP binding domain superfamily [IPR038535]", "CDC48 domain 2-like superfamily [IPR029067]", "CENP-B, dimerisation domain superfamily [IPR034882]", "CH domain superfamily [IPR036872]", "CRAL-TRIO lipid binding domain superfamily [IPR036865]", "CRAL/TRIO, N-terminal domain superfamily [IPR036273]", "CRIB domain superfamily [IPR036936]", "CSTF1, dimerization domain superfamily [IPR038184]", "Cadherin-like superfamily [IPR015919]", "Calcyclin-binding protein, N-terminal [IPR037201]", "Calpain large subunit, domain III superfamily [IPR036213]", "Calreticulin/calnexin, P domain superfamily [IPR009033]", "Calycin [IPR012674]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily [IPR036480]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily [IPR036897]", "Carbohydrate-binding-like fold [IPR013784]", "Carboxypeptidase-like, regulatory domain superfamily [IPR008969]", "Carnitine o-acyltransferase, N-terminal [IPR042572]", "Casein kinase II subunit beta-like [IPR035991]", "Casein kinase II, regulatory subunit, N-terminal [IPR016149]", "Catenin binding domain superfamily [IPR027397]", "Cathepsin C, exclusion domain superfamily [IPR036496]", "Cation efflux transmembrane domain superfamily [IPR027469]", "Cdc37, Hsp90-binding domain superfamily [IPR038189]", "Cell division control protein 73, C-terminal domain superfamily [IPR038103]", "Chaperone J-domain superfamily [IPR036869]", "Chitinase insertion domain superfamily [IPR029070]", "Chloramphenicol acetyltransferase-like domain superfamily [IPR023213]", "Chloride channel, core [IPR014743]", "Choline/Carnitine o-acyltransferase, domain 2 [IPR042231]", "Chromo-like domain superfamily [IPR016197]", "Citrate synthase superfamily [IPR036969]", "Citrate synthase-like, large alpha subdomain [IPR016142]", "Citrate synthase-like, small alpha subdomain [IPR016143]", "Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm [IPR010978]", "Class I glutamine amidotransferase-like [IPR029062]", "Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) [IPR045864]", "Class II aldolase/adducin N-terminal domain superfamily [IPR036409]", "Clathrin adaptor, appendage, Ig-like subdomain superfamily [IPR013041]", "Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain [IPR013037]", "Clathrin heavy chain, N-terminal [IPR016025]", "ClpP/crotonase-like domain superfamily [IPR029045]", "Coatomer, gamma subunit, appendage domain superfamily [IPR037067]", "Coatomer/calthrin adaptor appendage, C-terminal subdomain [IPR009028]", "Cobalamin (vitamin B12)-dependent enzyme, catalytic [IPR016176]", "Cobalamin adenosyltransferase-like superfamily [IPR036451]", "Cobalamin-binding domain superfamily [IPR036724]", "Concanavalin A-like lectin/glucanase domain superfamily [IPR013320]", "Creatinase/Aminopeptidase P/Spt16, N-terminal [IPR029149]", "Creatinase/aminopeptidase-like [IPR036005]", "Cullin homology domain superfamily [IPR036317]", "Cullin repeat-like-containing domain superfamily [IPR016159]", "Cupredoxin [IPR008972]", "Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal [IPR016098]", "Cyclic nucleotide-binding-like [IPR018490]", "Cyclic phosphodiesterase [IPR009097]", "Cyclin-like superfamily [IPR036915]", "Cyclophilin-like domain superfamily [IPR029000]", "Cytidine deaminase-like [IPR016193]", "Cytochrome C oxidase subunit II, transmembrane domain superfamily [IPR036257]", "Cytochrome P450 superfamily [IPR036396]", "Cytochrome b-c1 complex subunit 7 superfamily [IPR036544]", "Cytochrome b-c1 complex subunit 8 superfamily [IPR036642]", "Cytochrome b-c1 complex subunit 9 superfamily [IPR036656]", "Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400]", "Cytochrome bc1 complex subunit Rieske, transmembrane domain superfamily [IPR037008]", "Cytochrome c oxidase subunit IV superfamily [IPR036639]", "Cytochrome c oxidase subunit VIIc superfamily [IPR036636]", "Cytochrome c oxidase, subunit VIIa superfamily [IPR036539]", "Cytochrome c oxidase, subunit Va/VI superfamily [IPR036545]", "Cytochrome c oxidase, subunit Vb superfamily [IPR036972]", "Cytochrome c-like domain superfamily [IPR036909]", "Cytochrome c1, transmembrane anchor, C-terminal [IPR021157]", "Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily [IPR011048]", "DCN1-like, PONY binding domain [IPR042460]", "DENN domain, C-terminal lobe [IPR043153]", "DHS-like NAD/FAD-binding domain superfamily [IPR029035]", "DIX domain superfamily [IPR038207]", "DNA breaking-rejoining enzyme, catalytic core [IPR011010]", "DNA fragmentation factor 45kDa, C-terminal [IPR027296]", "DNA glycosylase [IPR011257]", "DNA ligase, ATP-dependent, N-terminal domain superfamily [IPR036599]", "DNA mismatch repair protein MutS, N-terminal [IPR016151]", "DNA mismatch repair protein MutS, core domain superfamily [IPR036187]", "DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal [IPR008921]", "DNA polymerase alpha, subunit B, N-terminal domain superfamily [IPR043034]", "DNA polymerase alpha, zinc finger domain superfamily [IPR038256]", "DNA polymerase family B, thumb domain [IPR042087]", "DNA polymerase, palm domain superfamily [IPR023211]", "DNA repair protein XRCC4-like, C-terminal [IPR014751]", "DNA topoisomerase I, DNA binding, N-terminal domain 1 [IPR013034]", "DNA topoisomerase I, DNA binding, N-terminal domain 2 [IPR013030]", "DNA topoisomerase I, DNA binding, eukaryotic-type, N-terminal domain superfamily [IPR036202]", "DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type [IPR014711]", "DNA topoisomerase I, catalytic core, alpha/beta subdomain [IPR014727]", "DNA topoisomerase, type IA, central region, subdomain 1 [IPR013824]", "DNA topoisomerase, type IA, central region, subdomain 2 [IPR013825]", "DNA topoisomerase, type IA, central region, subdomain 3 [IPR013826]", "DNA topoisomerase, type IA, core domain [IPR023405]", "DNA topoisomerase, type IIA, alpha-helical domain superfamily [IPR013757]", "DNA topoisomerase, type IIA, domain A, alpha-beta [IPR013758]", "DNA topoisomerase, type IIA, subunit B, C-terminal [IPR013759]", "DNA topoisomerase, type IIA-like domain superfamily [IPR013760]", "DNA-binding domain superfamily [IPR016177]", "DNA-directed RNA polymerase, N-terminal domain superfamily [IPR037159]", "DNA-directed RNA polymerase, insert domain superfamily [IPR036643]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily [IPR037033]", "DNA/RNA non-specific endonuclease superfamily [IPR044929]", "DNA/RNA polymerase superfamily [IPR043502]", "DNA/RNA-binding protein KIN17, WH-like domain superfamily [IPR038254]", "DUSP-like superfamily [IPR035927]", "Daxx, N-terminal domain superfamily [IPR038298]", "Dbl homology (DH) domain superfamily [IPR035899]", "Death-like domain superfamily [IPR011029]", "Dedicator of cytokinesis, C-terminal, lobe A [IPR043161]", "Dedicator of cytokinesis, C-terminal, lobe C [IPR043162]", "Deoxyhypusine synthase superfamily [IPR036982]", "Diaphanous, GTPase-binding domain superfamily [IPR044933]", "Dicer dimerisation domain superfamily [IPR038248]", "Dihydrofolate reductase-like domain superfamily [IPR024072]", "Dihydropteroate synthase-like [IPR011005]", "Dimeric alpha-beta barrel [IPR011008]", "Diphthamide synthesis DPH1/DPH2, domain 1 [IPR042263]", "Diphthamide synthesis DPH1/DPH2, domain 3 [IPR042265]", "Disintegrin domain superfamily [IPR036436]", "Dynein heavy chain AAA lid domain superfamily [IPR042219]", "Dynein heavy chain, AAA1 domain, small subdomain [IPR043157]", "Dynein heavy chain, C-terminal domain, barrel region [IPR043160]", "Dynein heavy chain, domain 2, N-terminal [IPR042222]", "Dynein heavy chain, linker, subdomain 3 [IPR042228]", "Dynein light chain superfamily [IPR037177]", "E2 domain superfamily [IPR036176]", "E3-binding domain superfamily [IPR036625]", "EB1, C-terminal domain superfamily [IPR036133]", "EF-G domain III/V-like [IPR035647]", "EF-hand domain pair [IPR011992]", "ENTH/VHS [IPR008942]", "ERO1-like superfamily [IPR037192]", "ERV/ALR sulfhydryl oxidase domain superfamily [IPR036774]", "ESCRT assembly domain [IPR037202]", "ESCRT-II complex, Vps25 subunit, N-terminal winged helix [IPR014041]", "EXOC6/PINT-1/Sec15/Tip20, C-terminal, domain 2 [IPR042044]", "EYA domain superfamily [IPR038102]", "Elongation factor EF1B gamma, C-terminal domain superfamily [IPR036433]", "Elongation factor Ts, dimerisation domain superfamily [IPR036402]", "Endonuclease/exonuclease/phosphatase superfamily [IPR036691]", "Endoplasmic reticulum resident protein 29, C-terminal domain superfamily [IPR036356]", "Enhancer of mRNA-decapping protein 4, conserved C-terminal domain [IPR044938]", "Enhancer of rudimentary superfamily [IPR035912]", "Enolase-like, C-terminal domain superfamily [IPR036849]", "Enolase-like, N-terminal [IPR029017]", "Enoyl-CoA hydratase, C-terminal [IPR014748]", "Eukaryotic translation initiation factor 3-like domain superfamily [IPR023194]", "Exocyst complex component EXOC3/Sec6, C-terminal domain [IPR042532]", "Exocyst complex component EXOC6/Sec15, C-terminal, domain 1 [IPR042045]", "Exoribonuclease, PH domain 2 superfamily [IPR036345]", "F-actin capping protein, alpha subunit, domain 1 [IPR042489]", "F-actin-capping protein subunit alpha/beta [IPR037282]", "F-actin-capping protein subunit alpha/beta, domain 2 [IPR042276]", "F-actin-capping protein subunit beta, N-terminal domain [IPR043175]", "F-box-like domain superfamily [IPR036047]", "F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily [IPR026015]", "FAD-binding, type PCMH, subdomain 1 [IPR016167]", "FAD-binding, type PCMH, subdomain 2 [IPR016169]", "FAD-binding, type PCMH-like superfamily [IPR036318]", "FAD-linked oxidase-like, C-terminal [IPR016164]", "FAD/NAD(P)-binding domain superfamily [IPR036188]", "FAD/NAD-linked reductase, dimerisation domain superfamily [IPR016156]", "FCS-type zinc finger superfamily [IPR038603]", "FERM superfamily, second domain [IPR035963]", "FERM/acyl-CoA-binding protein superfamily [IPR014352]", "FF domain superfamily [IPR036517]", "FIP-RBD, C-terminal domain superfamily [IPR037245]", "FKBP12-rapamycin binding domain superfamily [IPR036738]", "FMN-binding split barrel [IPR012349]", "FTO, C-terminal domain superfamily [IPR038413]", "Fe-S cluster assembly domain superfamily [IPR034904]", "Ferredoxin-NADP reductase (FNR), nucleotide-binding domain [IPR039261]", "Ferritin-like superfamily [IPR009078]", "Fibronectin type II domain superfamily [IPR036943]", "Fibronectin type III superfamily [IPR036116]", "Flavoprotein-like superfamily [IPR029039]", "Formin, FH2 domain superfamily [IPR042201]", "Formyl transferase, N-terminal domain superfamily [IPR036477]", "Formyl transferase-like, C-terminal domain superfamily [IPR011034]", "Fumarase/histidase, N-terminal [IPR024083]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily [IPR037099]", "Fumarylacetoacetase, N-terminal domain superfamily [IPR036462]", "Fumarylacetoacetase-like, C-terminal domain superfamily [IPR036663]", "G protein alpha subunit, helical insertion [IPR011025]", "G-protein gamma-like domain superfamily [IPR036284]", "GAD-like domain superfamily [IPR004115]", "GAR domain superfamily [IPR036534]", "GAT domain superfamily [IPR038425]", "GBBH-like, N-terminal domain superfamily [IPR038492]", "GHMP kinase, C-terminal domain superfamily [IPR036554]", "GINS complex, subunit Psf3 superfamily [IPR038437]", "GINS, helical bundle-like domain superfamily [IPR036224]", "GM2-AP, lipid-recognition domain superfamily [IPR036846]", "GMP phosphodiesterase, delta subunit superfamily [IPR037036]", "GOLD domain superfamily [IPR036598]", "GSKIP domain superfamily [IPR023231]", "GTF2I-like repeat superfamily [IPR036647]", "GTP-binding protein TrmE/Aminomethyltransferase GcvT, domain 1 [IPR027266]", "GTP-binding protein, orthogonal bundle domain superfamily [IPR023179]", "GTP1/OBG domain superfamily [IPR036726]", "GYF-like domain superfamily [IPR035445]", "Galactose mutarotase-like domain superfamily [IPR011013]", "Galactose oxidase/kelch, beta-propeller [IPR011043]", "Galactose-binding-like domain superfamily [IPR008979]", "Gamma-glutamyl cyclotransferase-like superfamily [IPR036568]", "Gamma-tubulin complex component, C-terminal domain superfamily [IPR042241]", "Gelsolin-like domain superfamily [IPR036180]", "Globular protein, non-globular alpha/beta subunit [IPR011070]", "Glu-tRNAGln amidotransferase superfamily, subunit C [IPR036113]", "Glutamine synthetase/guanido kinase, catalytic domain [IPR014746]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 1 [IPR042558]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 2 [IPR042559]", "Glutathione S-transferase, C-terminal domain superfamily [IPR036282]", "Glutathione synthase, C-terminal, eukaryotic [IPR014709]", "Glutathione synthase, N-terminal, eukaryotic [IPR014049]", "Glutathione synthase, alpha-helical [IPR014042]", "Glutathione synthase, substrate-binding domain superfamily [IPR037013]", "Glycine cleavage T-protein/YgfZ, C-terminal [IPR029043]", "Glycoside hydrolase 38, N-terminal domain superfamily [IPR027291]", "Glycoside hydrolase families 57/38, central domain superfamily [IPR028995]", "Glycoside hydrolase family 38, central domain superfamily [IPR037094]", "Glycoside hydrolase superfamily [IPR017853]", "Glycoside hydrolase-type carbohydrate-binding [IPR014718]", "Glycoside hydrolase/deacetylase, beta/alpha-barrel [IPR011330]", "Glycosyl hydrolase family 63, N-terminal domain superfamily [IPR038518]", "Glycosyl hydrolase, all-beta [IPR013780]", "Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [IPR029068]", "Golgi phosphoprotein 3-like domain superfamily [IPR038261]", "GroEL-like apical domain superfamily [IPR027409]", "GroEL-like equatorial domain superfamily [IPR027413]", "GroES chaperonin superfamily [IPR037124]", "GroES-like superfamily [IPR011032]", "Growth arrest and DNA damage-inducible proteins-interacting protein 1 domain superfamily [IPR043035]", "Growth factor receptor cysteine-rich domain superfamily [IPR009030]", "GrpE nucleotide exchange factor, coiled-coil [IPR013805]", "GrpE nucleotide exchange factor, head [IPR009012]", "Guanylate-binding protein, C-terminal domain superfamily [IPR036543]", "H/ACA RNP complex subunit Gar1/Naf1, Cbf5-binding domain [IPR038664]", "HAD superfamily [IPR023214]", "HAD-like superfamily [IPR036412]", "HAD-superfamily hydrolase, subfamily IA, REG-2-like, capping domain superfamily [IPR044924]", "HBS1-like protein, N-terminal domain superfamily [IPR037189]", "HECT, E3 ligase catalytic domain [IPR035983]", "HIT-like superfamily [IPR036265]", "HIV integrase-binding domain superfamily [IPR036218]", "HORMA domain superfamily [IPR036570]", "HR1 repeat superfamily [IPR036274]", "HRDC domain superfamily [IPR044876]", "HRDC-like superfamily [IPR010997]", "HSP20-like chaperone [IPR008978]", "HSP40/DnaJ peptide-binding [IPR008971]", "HSP90, C-terminal domain [IPR037196]", "Haem oxygenase-like, multi-helical [IPR016084]", "Heat shock protein 70kD, C-terminal domain superfamily [IPR029048]", "Heat shock protein 70kD, peptide-binding domain superfamily [IPR029047]", "Heat shock protein DnaJ, cysteine-rich domain superfamily [IPR036410]", "Heavy metal-associated domain superfamily [IPR036163]", "Helix hairpin bin domain superfamily [IPR029012]", "Helix-hairpin-helix, base-excision DNA repair, C-terminal [IPR023170]", "Hemimethylated DNA-binding domain superfamily [IPR036623]", "High mobility group box domain superfamily [IPR036910]", "His-Me finger superfamily [IPR044925]", "Histidine kinase/HSP90-like ATPase superfamily [IPR036890]", "Histidine phosphatase superfamily [IPR029033]", "Histone acetyl transferase 1, N-terminal domain superfamily [IPR037113]", "Histone acetyltransferase HAT1, C-terminal [IPR013523]", "Histone deacetylase domain superfamily [IPR037138]", "Histone-fold [IPR009072]", "Homeobox-like domain superfamily [IPR009057]", "Homocysteine-binding domain superfamily [IPR036589]", "HotDog domain superfamily [IPR029069]", "I/LWEQ domain superfamily [IPR035964]", "ISWI, HAND domain superfamily [IPR036306]", "Immunoglobulin E-set [IPR014756]", "Immunoglobulin-like domain superfamily [IPR036179]", "Immunoglobulin-like fold [IPR013783]", "Importin-alpha, importin-beta-binding domain superfamily [IPR036975]", "Initiation factor 2B-like, C-terminal [IPR042529]", "Inorganic polyphosphate/ATP-NAD kinase, N-terminal [IPR017438]", "Inorganic pyrophosphatase superfamily [IPR036649]", "Inosine triphosphate pyrophosphatase-like [IPR029001]", "Integrase-like, N-terminal [IPR017856]", "Integrin beta tail domain superfamily [IPR036349]", "Integrin domain superfamily [IPR032695]", "Interferon regulatory factor 2-binding protein 1/2, C3HC4-type RING finger superfamily [IPR044882]", "Invasin/intimin cell-adhesion fragments [IPR008964]", "Isochorismatase-like superfamily [IPR036380]", "Isopenicillin N synthase-like superfamily [IPR027443]", "Isoprenoid synthase domain superfamily [IPR008949]", "K Homology domain, type 1 superfamily [IPR036612]", "K homology domain superfamily, prokaryotic type [IPR009019]", "K homology domain-like, alpha/beta [IPR015946]", "KA1 domain/Ssp2, C-terminal [IPR028375]", "Kazal domain superfamily [IPR036058]", "Kelch-type beta propeller [IPR015915]", "Kinesin motor domain superfamily [IPR036961]", "Kinesin-like protein Kif23, Arf6-interacting domain superfamily [IPR038105]", "Kringle-like fold [IPR013806]", "Ku, C-terminal domain superfamily [IPR036494]", "Ku70, bridge and pillars domain superfamily [IPR027388]", "L-Aspartase-like [IPR008948]", "L21-like superfamily [IPR036164]", "L27 domain superfamily [IPR036892]", "L28p-like [IPR034704]", "LAP1C-like, C-terminal domain superfamily [IPR038599]", "LDL receptor-like superfamily [IPR036055]", "LEM/LEM-like domain superfamily [IPR011015]", "LIS1, N-terminal [IPR037190]", "LSM domain superfamily [IPR010920]", "Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal [IPR015955]", "Lambda repressor-like, DNA-binding domain superfamily [IPR010982]", "Lamin tail domain superfamily [IPR036415]", "LepA, C-terminal domain superfamily [IPR038363]", "Leucine-rich repeat domain superfamily [IPR032675]", "LexA/Signal peptidase-like superfamily [IPR036286]", "Longin-like domain superfamily [IPR011012]", "MAGE homology domain, winged helix WH1 motif [IPR041898]", "MAGE homology domain, winged helix WH2 motif [IPR041899]", "MAN1, winged-helix domain [IPR041885]", "MFS transporter superfamily [IPR036259]", "MHC class I-like antigen recognition-like superfamily [IPR037055]", "MHC classes I/II-like antigen recognition protein [IPR011162]", "MIT domain superfamily [IPR036181]", "MOB kinase activator superfamily [IPR036703]", "MRG, C-terminal domain superfamily [IPR038217]", "MRP-L47 superfamily, mitochondrial [IPR038340]", "MTH938-like superfamily [IPR036748]", "Macro domain-like [IPR043472]", "Malic enzyme, N-terminal domain superfamily [IPR037062]", "Malonyl-CoA ACP transacylase, ACP-binding [IPR016036]", "Manganese/iron superoxide dismutase, C-terminal domain superfamily [IPR036314]", "Manganese/iron superoxide dismutase, N-terminal domain superfamily [IPR036324]", "Mannose-6-phosphate receptor binding domain superfamily [IPR009011]", "Mediator complex subunit 25, PTOV domain superfamily [IPR038196]", "Mediator complex, subunit Med7/Med21-like [IPR037212]", "Membrane associated eicosanoid/glutathione metabolism-like domain superfamily [IPR023352]", "Metal-dependent hydrolase [IPR032466]", "Metal-dependent hydrolase, composite domain superfamily [IPR011059]", "Metallo-dependent phosphatase-like [IPR029052]", "Metalloenzyme, LuxS/M16 peptidase-like [IPR011249]", "Metallopeptidase, catalytic domain superfamily [IPR024079]", "Methionine synthase domain [IPR036594]", "Methionyl-tRNA synthetase, Zn-domain [IPR029038]", "Methylglyoxal synthase-like domain superfamily [IPR036914]", "Methylpurine-DNA glycosylase superfamily [IPR036995]", "Methylthiotransferase, N-terminal domain superfamily [IPR038135]", "Mib/herc2 domain superfamily [IPR037252]", "MitoNEET, CDGSH iron-sulfur domain [IPR042216]", "Mitochondrial carrier domain superfamily [IPR023395]", "Mitochondrial cytochrome c oxidase subunit VIc/VIIs superfamily [IPR037169]", "Mitochondrial glycoprotein superfamily [IPR036561]", "Mitochondrial outer membrane translocase complex, Tom20 domain superfamily [IPR023392]", "Mitochondrial ribosomal protein L55 superfamily [IPR044884]", "MoaB/Mog-like domain superfamily [IPR036425]", "MoeA, C-terminal, domain IV superfamily [IPR036688]", "MoeA, N-terminal and linker domain superfamily [IPR036135]", "Moesin tail domain superfamily [IPR008954]", "Mre11, capping domain [IPR038487]", "Mss4-like superfamily [IPR011057]", "Mss4/translationally controlled tumour-associated TCTP [IPR011323]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain superfamily [IPR042179]", "MutS, connector domain superfamily [IPR036678]", "Myosin S1 fragment, N-terminal [IPR008989]", "NAC A/B domain superfamily [IPR038187]", "NAD kinase/diacylglycerol kinase-like domain superfamily [IPR016064]", "NAD(P)-binding domain superfamily [IPR036291]", "NADH-quinone oxidoreductase subunit E, N-terminal [IPR041921]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily [IPR037225]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily [IPR037207]", "NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily [IPR037232]", "NADP-dependent oxidoreductase domain superfamily [IPR036812]", "NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamily [IPR023173]", "NAP-like superfamily [IPR037231]", "NET domain superfamily [IPR038336]", "NFRKB winged helix-like domain superfamily [IPR038106]", "NO signalling/Golgi transport ligand-binding domain superfamily [IPR024096]", "NOB1 zinc finger-like superfamily [IPR036283]", "NSFL1 cofactor p47, SEP domain superfamily [IPR036241]", "NTF2-like domain superfamily [IPR032710]", "NUDIX hydrolase-like domain superfamily [IPR015797]", "NVL2, N-terminal domain superfamily [IPR038100]", "NagB/RpiA transferase-like [IPR037171]", "Neurolysin/Thimet oligopeptidase, N-terminal [IPR024080]", "Neurolysin/Thimet oligopeptidase, domain 2 [IPR024077]", "Nibrin, second BRCT domain superfamily [IPR043014]", "Nicotinate phosphoribosyltransferase-like, C-terminal [IPR036068]", "Nitrogen regulatory PII-like, alpha/beta [IPR011322]", "Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal [IPR015867]", "Nitrous oxide reductase, N-terminal [IPR011045]", "Nop domain superfamily [IPR036070]", "Nop, C-terminal domain [IPR042239]", "Nuclear hormone receptor-like domain superfamily [IPR035500]", "Nucleic acid-binding, OB-fold [IPR012340]", "Nucleophile aminohydrolases, N-terminal [IPR029055]", "Nucleoplasmin core domain superfamily [IPR036824]", "Nucleoporin, Nup155-like, C-terminal, subdomain 1 [IPR042533]", "Nucleoporin, Nup155-like, C-terminal, subdomain 2 [IPR042537]", "Nucleoporin, Nup155-like, C-terminal, subdomain 3 [IPR042538]", "Nucleoside diphosphate kinase-like domain superfamily [IPR036850]", "Nucleoside phosphorylase superfamily [IPR035994]", "Nucleotide-binding alpha-beta plait domain superfamily [IPR012677]", "Nucleotide-diphospho-sugar transferases [IPR029044]", "Nucleotidyltransferase superfamily [IPR043519]", "Nucleotidyltransferase, class I-like, C-terminal [IPR011068]", "Nuf2, N-terminal domain superfamily [IPR038275]", "NusG, N-terminal domain superfamily [IPR036735]", "Oxygen-dependent coproporphyrinogen III oxidase superfamily [IPR036406]", "Oxysterol-binding protein superfamily [IPR037239]", "P-loop containing nucleoside triphosphate hydrolase [IPR027417]", "P-type ATPase, A domain superfamily [IPR008250]", "P-type ATPase, cytoplasmic domain N [IPR023299]", "P-type ATPase, transmembrane domain superfamily [IPR023298]", "P-type trefoil domain superfamily [IPR044913]", "PABC (PABP) domain [IPR036053]", "PADR1 domain superfamily [IPR038650]", "PAZ domain superfamily [IPR036085]", "PBDC1-like domain superfamily [IPR023139]", "PCGF Ub-like fold discriminator superfamily [IPR038227]", "PD-(D/E)XK endonuclease-like domain superfamily [IPR011604]", "PDCD5-like superfamily [IPR036883]", "PDZ superfamily [IPR036034]", "PEBP-like superfamily [IPR036610]", "PFU domain superfamily [IPR038122]", "PH-like domain superfamily [IPR011993]", "PHR domain superfamily [IPR038648]", "PIN-like domain superfamily [IPR029060]", "PITH domain superfamily [IPR037047]", "PKD domain superfamily [IPR035986]", "PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily [IPR017946]", "PLP-binding barrel [IPR029066]", "PNPase/RNase PH domain superfamily [IPR027408]", "POLO box domain superfamily [IPR036947]", "PPM-type phosphatase domain superfamily [IPR036457]", "PRP4-like superfamily [IPR036285]", "PTPA superfamily [IPR037218]", "PUA domain superfamily [IPR036974]", "PUA-like superfamily [IPR015947]", "PWI domain superfamily [IPR036483]", "PX domain superfamily [IPR036871]", "Paired amphipathic helix superfamily [IPR036600]", "Pancreatic trypsin inhibitor Kunitz domain superfamily [IPR036880]", "PapD-like superfamily [IPR008962]", "Papain-like cysteine peptidase superfamily [IPR038765]", "Pectin lyase fold [IPR012334]", "Pectin lyase fold/virulence factor [IPR011050]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase superfamily [IPR036959]", "Peptidase C65, otubain, subdomain 2 [IPR042467]", "Peptidase C65, otubain, subdomain 1 [IPR042468]", "Peptidase M1, LTA-4 hydrolase/aminopeptidase, C-terminal domain superfamily [IPR038502]", "Peptidase M13, domain 2 [IPR042089]", "Peptidase M4/M1, CTD superfamily [IPR027268]", "Peptidase M41-like [IPR037219]", "Peptidase M60, enhancin-like domain 3 [IPR042279]", "Peptidase S1, PA clan [IPR009003]", "Peptidase S59, nucleoporin superfamily [IPR036903]", "Peptidase S8/S53 domain superfamily [IPR036852]", "Peptidyl-tRNA hydrolase II domain superfamily [IPR023476]", "Pex19, C-terminal domain superfamily [IPR038322]", "Phenylalanyl-tRNA synthetase-like, B3/B4 [IPR020825]", "Phosphatidic acid phosphatase type 2/haloperoxidase superfamily [IPR036938]", "Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily [IPR036940]", "Phosphatidylinositol-4-phosphate 5-kinase, N-terminal [IPR027484]", "Phosphoenolpyruvate carboxykinase, C-terminal [IPR013035]", "Phosphoenolpyruvate carboxykinase, N-terminal [IPR008210]", "Phosphofructokinase superfamily [IPR035966]", "Phosphoglucose isomerase, C-terminal [IPR023096]", "Phosphoglycerate kinase superfamily [IPR036043]", "Phosphoglycerate kinase, N-terminal [IPR015824]", "Phosphoglycolate phosphatase-like, domain 2 [IPR023198]", "Phosphoinositide 3-kinase, accessory (PIK) domain superfamily [IPR042236]", "Phospholipase B-like, domain 1 [IPR043040]", "Phospholipase B-like, domain 2 [IPR043041]", "Phospholipase B-like, domain 3 [IPR043042]", "Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily [IPR036604]", "Phosphoribosylglycinamide synthetase, C-domain superfamily [IPR037123]", "Phosphoribosyltransferase-like [IPR029057]", "Phosphorylated adapter RNA export protein, RNA-binding domain superfamily [IPR038092]", "Phosphotransferase/anion transporter [IPR016152]", "Phosphotyrosine protein phosphatase I superfamily [IPR036196]", "Phosphotyrosyl phosphatase activator, C-terminal lid domain [IPR043170]", "Plakin repeat superfamily [IPR035915]", "Poly(ADP-ribose) polymerase, regulatory domain superfamily [IPR036616]", "Polyketide synthase, dehydratase domain superfamily [IPR042104]", "Polymerase/histidinol phosphatase-like [IPR016195]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain superfamily [IPR036456]", "Porin domain superfamily [IPR023614]", "Porphobilinogen deaminase, C-terminal domain superfamily [IPR036803]", "Pre-ATP-grasp domain superfamily [IPR016185]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding domain superfamily [IPR042516]", "Pre-mRNA-splicing factor Isy1 superfamily [IPR037200]", "Prefoldin [IPR009053]", "Profilin superfamily [IPR036140]", "Prolyl-tRNA synthetase, class II [IPR017449]", "Proteasomal ubiquitin receptor Rpn13/ADRM1, Pru domain superfamily [IPR038633]", "Proteasome activator PA28, C-terminal domain superfamily [IPR036997]", "Proteasome activator PA28, N-terminal domain superfamily [IPR036996]", "Proteasome activator superfamily [IPR036252]", "Proteasome assembly chaperone 2 superfamily [IPR038389]", "Protein arginine methyltransferase NDUFAF7 superfamily [IPR038375]", "Protein kinase-like domain superfamily [IPR011009]", "Protein-tyrosine phosphatase-like [IPR029021]", "Prp8 RNase domain IV, fingers region [IPR043173]", "Prp8 RNase domain IV, palm region [IPR043172]", "Pseudouridine synthase I, TruA, C-terminal [IPR020095]", "Pseudouridine synthase TruA/RsuA/RluB/E/F, N-terminal [IPR020094]", "Pseudouridine synthase, TruD, catalytic domain [IPR042214]", "Pseudouridine synthase, catalytic domain superfamily [IPR020103]", "Pterin 4 alpha carbinolamine dehydratase superfamily [IPR036428]", "PurM-like, C-terminal domain superfamily [IPR036676]", "PurM-like, N-terminal domain superfamily [IPR036921]", "Putative DNA-binding domain superfamily [IPR009061]", "Putative deacetylase LmbE-like domain superfamily [IPR024078]", "Pyridoxal phosphate-dependent transferase [IPR015424]", "Pyridoxal phosphate-dependent transferase, major domain [IPR015421]", "Pyridoxal phosphate-dependent transferase, small domain [IPR015422]", "Pyruvate kinase, C-terminal domain superfamily [IPR036918]", "Pyruvate kinase, insert domain superfamily [IPR015806]", "Pyruvate kinase-like domain superfamily [IPR040442]", "Pyruvate kinase-like, insert domain superfamily [IPR011037]", "Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily [IPR015813]", "Queuine tRNA-ribosyltransferase-like [IPR036511]", "Quinoprotein alcohol dehydrogenase-like superfamily [IPR011047]", "Quinoprotein amine dehydrogenase, beta chain-like [IPR011044]", "R3H domain superfamily [IPR036867]", "RAP domain superfamily [IPR036744]", "RBP-J/Cbf11, DNA binding domain superfamily [IPR037095]", "RGS domain superfamily [IPR036305]", "RGS, subdomain 2 [IPR044926]", "RNA 3'-terminal phosphate cyclase domain superfamily [IPR037136]", "RNA 3'-terminal phosphate cyclase, insert domain superfamily [IPR036553]", "RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta [IPR013792]", "RNA polymerase Rpb1, clamp domain superfamily [IPR044893]", "RNA polymerase Rpb1, domain 3 superfamily [IPR042102]", "RNA polymerase Rpb1, domain 7 superfamily [IPR038593]", "RNA polymerase Rpb1, funnel domain superfamily [IPR038120]", "RNA polymerase Rpb2, OB-fold [IPR014724]", "RNA polymerase Rpb2, domain 2 superfamily [IPR037034]", "RNA polymerase Rpb5, N-terminal domain superfamily [IPR036710]", "RNA polymerase Rpb7-like, N-terminal domain superfamily [IPR036898]", "RNA polymerase subunit RPB10 [IPR023580]", "RNA polymerase, RBP11-like subunit [IPR036603]", "RNA-binding S4 domain superfamily [IPR036986]", "RNA-binding domain superfamily [IPR035979]", "RPB5-like RNA polymerase subunit superfamily [IPR035913]", "RPN13, DEUBAD domain superfamily [IPR038108]", "RRF superfamily [IPR036191]", "RUN domain superfamily [IPR037213]", "Rab geranylgeranyltransferase, alpha subunit, insert-domain superfamily [IPR036254]", "Rab-GTPase-TBC domain superfamily [IPR035969]", "Radical SAM, alpha/beta horseshoe [IPR023404]", "Ran-GTPase activating protein 1, C-terminal domain superfamily [IPR036720]", "Rap/Ran-GAP superfamily [IPR035974]", "Ras guanine nucleotide exchange factor domain superfamily [IPR023578]", "Ras guanine-nucleotide exchange factor, catalytic domain superfamily [IPR036964]", "Receptor L-domain superfamily [IPR036941]", "Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II [IPR009091]", "Regulatory factor, effector binding domain superfamily [IPR011256]", "Rel homology domain (RHD), DNA-binding domain superfamily [IPR037059]", "Restriction endonuclease type II-like [IPR011335]", "Rho GDP-dissociation inhibitor domain superfamily [IPR024792]", "Rho GTPase activation protein [IPR008936]", "Rhodanese-like domain superfamily [IPR036873]", "Rhomboid-like superfamily [IPR035952]", "Riboflavin synthase-like beta-barrel [IPR017938]", "Ribokinase-like [IPR029056]", "Ribonuclease H superfamily [IPR036397]", "Ribonuclease H-like superfamily [IPR012337]", "Ribonuclease H1, N-terminal domain superfamily [IPR037056]", "Ribonuclease HII, helix-loop-helix cap domain superfamily [IPR023160]", "Ribonuclease III, endonuclease domain superfamily [IPR036389]", "Ribonuclease P/MRP subunit Rpp29 superfamily [IPR036980]", "Ribonuclease T2-like superfamily [IPR036430]", "Ribonuclease Z/Hydroxyacylglutathione hydrolase-like [IPR036866]", "Ribonucleotide reductase R1 subunit, N-terminal [IPR008926]", "Ribonucleotide reductase-like [IPR012348]", "Ribosomal L15/L27a, N-terminal [IPR027386]", "Ribosomal L18e/L15P superfamily [IPR036227]", "Ribosomal RNA-processing protein 8, N-terminal domain [IPR042036]", "Ribosomal protein L1, 3-layer alpha/beta-sandwich [IPR016095]", "Ribosomal protein L1-like [IPR023674]", "Ribosomal protein L10-like domain superfamily [IPR043141]", "Ribosomal protein L10e/L16 superfamily [IPR036920]", "Ribosomal protein L11, C-terminal domain superfamily [IPR036769]", "Ribosomal protein L11/L12, N-terminal domain superfamily [IPR036796]", "Ribosomal protein L13 superfamily [IPR036899]", "Ribosomal protein L14 superfamily [IPR036853]", "Ribosomal protein L15e core domain superfamily [IPR024794]", "Ribosomal protein L17 superfamily [IPR036373]", "Ribosomal protein L19 superfamily [IPR038657]", "Ribosomal protein L19/L19e superfamily [IPR035970]", "Ribosomal protein L19/L19e, domain 1 [IPR015972]", "Ribosomal protein L2, domain 2 [IPR014722]", "Ribosomal protein L2, domain 3 [IPR014726]", "Ribosomal protein L20, C-terminal [IPR035566]", "Ribosomal protein L21 superfamily [IPR036948]", "Ribosomal protein L22/L17 superfamily [IPR036394]", "Ribosomal protein L22e superfamily [IPR038526]", "Ribosomal protein L23/L15e core domain superfamily [IPR012678]", "Ribosomal protein L24e/L24 superfamily [IPR038630]", "Ribosomal protein L25/Gln-tRNA synthetase, N-terminal [IPR020056]", "Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily [IPR011035]", "Ribosomal protein L27e superfamily [IPR038655]", "Ribosomal protein L28/L24 superfamily [IPR037147]", "Ribosomal protein L29/L35 superfamily [IPR036049]", "Ribosomal protein L3, domain 3, archaeal type superfamily [IPR044892]", "Ribosomal protein L30, ferredoxin-like fold domain superfamily [IPR036919]", "Ribosomal protein L31e domain superfamily [IPR023621]", "Ribosomal protein L32e superfamily [IPR036351]", "Ribosomal protein L35A superfamily [IPR038661]", "Ribosomal protein L36e domain superfamily [IPR038097]", "Ribosomal protein L37ae/L37e [IPR011331]", "Ribosomal protein L38e superfamily [IPR038464]", "Ribosomal protein L4 domain superfamily [IPR023574]", "Ribosomal protein L5 domain superfamily [IPR022803]", "Ribosomal protein L6, alpha-beta domain superfamily [IPR036789]", "Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like [IPR014719]", "Ribosomal protein L7/L12, oligomerisation domain superfamily [IPR036235]", "Ribosomal protein L9, N-terminal domain superfamily [IPR036935]", "Ribosomal protein L9/RNase H1, N-terminal [IPR009027]", "Ribosomal protein P1/P2, N-terminal domain [IPR038716]", "Ribosomal protein S10 domain superfamily [IPR036838]", "Ribosomal protein S11 superfamily [IPR036967]", "Ribosomal protein S13-like, H2TH [IPR010979]", "Ribosomal protein S14/S29 [IPR043140]", "Ribosomal protein S16 domain superfamily [IPR023803]", "Ribosomal protein S17e-like superfamily [IPR036401]", "Ribosomal protein S18 superfamily [IPR036870]", "Ribosomal protein S19/S15, superfamily [IPR023575]", "Ribosomal protein S2, flavodoxin-like domain superfamily [IPR023591]", "Ribosomal protein S21e superfamily [IPR038579]", "Ribosomal protein S26e superfamily [IPR038551]", "Ribosomal protein S3, C-terminal domain superfamily [IPR036419]", "Ribosomal protein S4e, central domain superfamily [IPR038237]", "Ribosomal protein S5 domain 2-type fold [IPR020568]", "Ribosomal protein S5 domain 2-type fold, subgroup [IPR014721]", "Ribosomal protein S7 domain superfamily [IPR036823]", "Ribosomal protein S8 superfamily [IPR035987]", "Ribosomal protein S8e subdomain, eukaryotes [IPR042563]", "Ribosome maturation protein SBDS, N-terminal domain superfamily [IPR036786]", "Ribosome maturation protein Sdo1/SBDS, central domain superfamily [IPR037188]", "Ribosome-associated complex head domain superfamily [IPR042569]", "Ribulose-phosphate binding barrel [IPR011060]", "Ricin B-like lectins [IPR035992]", "RmlC-like cupin domain superfamily [IPR011051]", "RmlC-like jelly roll fold [IPR014710]", "Rof/RNase P-like [IPR023534]", "Rossmann-like alpha/beta/alpha sandwich fold [IPR014729]", "Rpb4/RPC9 superfamily [IPR038324]", "Rudiment single hybrid motif [IPR011054]", "RutC-like superfamily [IPR035959]", "RuvA domain 2-like [IPR010994]", "RuvBL1/2, DNA/RNA binding domain [IPR042487]", "S-adenosyl-L-methionine-dependent methyltransferase [IPR029063]", "S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily [IPR023397]", "S-adenosylmethionine synthetase superfamily [IPR022636]", "S15/NS1, RNA-binding [IPR009068]", "SAP domain superfamily [IPR036361]", "SAS-6, N-terminal domain superfamily [IPR038558]", "SATB, CUTL domain superfamily [IPR038216]", "SATB, ULD domain superfamily [IPR038224]", "SCP2 sterol-binding domain superfamily [IPR036527]", "SGNH hydrolase superfamily [IPR036514]", "SH2 domain superfamily [IPR036860]", "SH3-like domain superfamily [IPR036028]", "SKP1-like, dimerisation domain superfamily [IPR036296]", "SKP1/BTB/POZ domain superfamily [IPR011333]", "SLED domain superfamily [IPR038348]", "SMAD/FHA domain superfamily [IPR008984]", "SMCs flexible hinge superfamily [IPR036277]", "SNARE [IPR010989]", "SNF2-like, N-terminal domain superfamily [IPR038718]", "SNase-like, OB-fold superfamily [IPR035437]", "SOS response associated peptidase-like [IPR036590]", "SPOC-like, C-terminal domain superfamily [IPR016194]", "SRA-YDG superfamily [IPR036987]", "SRCR-like domain superfamily [IPR036772]", "SRP/SRP receptor, N-terminal [IPR036225]", "SRP68, N-terminal domain superfamily [IPR038253]", "SSRP1 domain superfamily [IPR038167]", "START-like domain superfamily [IPR023393]", "STAT transcription factor, DNA-binding, N-terminal [IPR012345]", "STAT transcription factor, N-terminal domain superfamily [IPR036535]", "STAT transcription factor, coiled coil [IPR015988]", "STAT1, C-terminal domain superfamily [IPR038295]", "SUI1 domain superfamily [IPR036877]", "SWAP/Surp superfamily [IPR035967]", "SWIB/MDM2 domain superfamily [IPR036885]", "Saposin-like [IPR011001]", "Scaffold protein Nfu/NifU, N-terminal domain superfamily [IPR036498]", "Scavenger mRNA decapping enzyme, N-terminal [IPR011145]", "Schlafen, AlbA_2 domain superfamily [IPR038461]", "ScpA-like, C-terminal [IPR023093]", "Sec1-like superfamily [IPR036045]", "Sec1-like, domain 1 [IPR043154]", "Sec1-like, domain 2 [IPR027482]", "Sec1-like, domain 3a [IPR043127]", "Sec23/Sec24 helical domain superfamily [IPR036175]", "Sec7 domain superfamily [IPR035999]", "Sec7, C-terminal domain superfamily [IPR023394]", "SecY domain superfamily [IPR023201]", "Secretoglobin superfamily [IPR035960]", "Sema domain superfamily [IPR036352]", "Serine carboxypeptidase S28, SKS domain [IPR042269]", "Serine-tRNA synthetase, type1, N-terminal domain superfamily [IPR042103]", "Serpin superfamily [IPR036186]", "Serpin superfamily, domain 1 [IPR042178]", "Serpin superfamily, domain 2 [IPR042185]", "Seven-hairpin glycosidases [IPR036026]", "Sialidase superfamily [IPR036278]", "Signal recognition particle SRP54, N-terminal domain superfamily [IPR042101]", "Signal recognition particle, SRP54 subunit, M-domain superfamily [IPR036891]", "Signal recognition particle, SRP9/SRP14 subunit [IPR009018]", "Signal recognition particle, subunit SRP19-like superfamily [IPR036521]", "Sin3 associated polypeptide p18 superfamily [IPR042534]", "Single hybrid motif [IPR011053]", "Sirtuin, catalytic core small domain superfamily [IPR026591]", "Six-bladed beta-propeller, TolB-like [IPR011042]", "Six-hairpin glycosidase superfamily [IPR008928]", "Six-hairpin glycosidase-like superfamily [IPR012341]", "Smac/DIABLO-like superfamily [IPR009062]", "Smaug, PHAT domain superfamily [IPR037093]", "Sodium/glucose symporter superfamily [IPR038377]", "Sodium/potassium-transporting ATPase subunit beta superfamily [IPR038702]", "Sodium:dicarboxylate symporter superfamily [IPR036458]", "Sodium:neurotransmitter symporter superfamily [IPR037272]", "Soluble quinoprotein glucose/sorbosone dehydrogenase [IPR011041]", "Somatomedin B-like domain superfamily [IPR036024]", "Spermadhesin, CUB domain superfamily [IPR035914]", "Spermidine synthase, tetramerisation domain superfamily [IPR037163]", "Spt6, Death-like domain [IPR042066]", "Stathmin superfamily [IPR036002]", "Sterile alpha motif/pointed domain superfamily [IPR013761]", "Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily [IPR027477]", "Succinyl-CoA synthetase-like [IPR016102]", "Sulfatase-modifying factor enzyme superfamily [IPR042095]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain superfamily [IPR042568]", "TAFH/NHR1 domain superfamily [IPR037249]", "TAP42/TAP46-like superfamily [IPR038511]", "TBP domain superfamily [IPR012295]", "TCP-1-like chaperonin intermediate domain superfamily [IPR027410]", "TEL2, C-terminal domain superfamily [IPR038528]", "TFIIIC, subcomplex tauA subunit Sfc1, triple barrel domain superfamily [IPR042536]", "TFIIS/LEDGF domain superfamily [IPR035441]", "TGS-like [IPR012676]", "TGS-like domain superfamily [IPR023192]", "TMEM14 superfamily [IPR044890]", "TRAF-like [IPR008974]", "TRF2-interacting telomeric protein/Rap1, C-terminal domain superfamily [IPR038104]", "TROVE domain superfamily [IPR037214]", "TTC5, OB fold domain superfamily [IPR038645]", "Talin, central domain superfamily [IPR036476]", "Taurine dioxygenase TauD-like superfamily [IPR042098]", "Tautomerase/MIF superfamily [IPR014347]", "Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid [IPR008930]", "Tetrapyrrole methylase superfamily [IPR035996]", "Tetrapyrrole methylase, subdomain 1 [IPR014777]", "Tetrapyrrole methylase, subdomain 2 [IPR014776]", "Tetraspanin, EC2 domain superfamily [IPR008952]", "Tetratricopeptide-like helical domain superfamily [IPR011990]", "Tex-like domain superfamily [IPR023323]", "Tex-like protein, HTH domain superfamily [IPR023319]", "Thiamin diphosphate-binding fold [IPR029061]", "Thiolase-like [IPR016039]", "Thioredoxin-like superfamily [IPR036249]", "Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily [IPR018163]", "Thymidylate synthase/dCMP hydroxymethylase superfamily [IPR036926]", "Tim10-like domain superfamily [IPR035427]", "Tma16 superfamily [IPR038356]", "Toll/interleukin-1 receptor homology (TIR) domain superfamily [IPR035897]", "Transcription Factor IIF, Rap30/Rap74, interaction [IPR011039]", "Transcription elongation factor S-II, central domain superfamily [IPR036575]", "Transcription termination and cleavage factor, C-terminal domain superfamily [IPR038192]", "Transcriptional regulator TACO1-like, domain 3 [IPR026564]", "Transferrin receptor-like, dimerisation domain superfamily [IPR036757]", "Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II [IPR009014]", "Translation Initiation factor eIF- 4e-like [IPR023398]", "Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal [IPR009001]", "Translation elongation factor EF1B/ribosomal protein S6 [IPR014717]", "Translation elongation factor eEF-1beta-like superfamily [IPR036219]", "Translation initiation factor 2, alpha subunit, C-terminal [IPR024055]", "Translation initiation factor 2, alpha subunit, middle domain superfamily [IPR024054]", "Translation initiation factor 3, subunit 12, N-terminal, eukaryotic [IPR016020]", "Translation initiation factor IF-2, domain 3 superfamily [IPR036925]", "Translation initiation factor IF2/IF5, N-terminal [IPR016189]", "Translation initiation factor IF2/IF5, zinc-binding [IPR016190]", "Translation initiation factor eIF-2B subunit alpha, N-terminal [IPR042528]", "Translation protein SH3-like domain superfamily [IPR008991]", "Translation protein, beta-barrel domain superfamily [IPR009000]", "Translin superfamily [IPR036081]", "Translin, C-terminal [IPR016069]", "Translin, N-terminal [IPR016068]", "Trimeric LpxA-like superfamily [IPR011004]", "Triosephosphate isomerase superfamily [IPR035990]", "TspO/MBR-related superfamily [IPR038330]", "Tubulin binding cofactor A superfamily [IPR036126]", "Tubulin, C-terminal [IPR023123]", "Tubulin/FtsZ, C-terminal [IPR008280]", "Tubulin/FtsZ, GTPase domain superfamily [IPR036525]", "Tubulin/FtsZ-like, C-terminal domain [IPR037103]", "UBA-like superfamily [IPR009060]", "UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily [IPR036220]", "UROD/MetE-like superfamily [IPR038071]", "Ubiquitin activating enzyme, alpha domain superfamily [IPR023318]", "Ubiquitin-activating enzyme E1, C-terminal domain superfamily [IPR038252]", "Ubiquitin-activating enzyme E1, FCCH domain superfamily [IPR042302]", "Ubiquitin-activating enzyme E1, SCCH domain [IPR042063]", "Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1 [IPR042449]", "Ubiquitin-activating enzyme [IPR035985]", "Ubiquitin-conjugating enzyme/RWD-like [IPR016135]", "Ubiquitin-like domain superfamily [IPR029071]", "Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain superfamily [IPR042556]", "Ufd1-like, Nn domain [IPR042299]", "Ureohydrolase domain superfamily [IPR023696]", "V-type ATP synthase c/d subunit, domain 3 superfamily [IPR044911]", "V-type ATP synthase subunit c/d subunit superfamily [IPR036079]", "V-type ATPase subunit C/d [IPR035067]", "V-type ATPase subunit E, C-terminal domain superfamily [IPR038495]", "VASP tetramerisation domain superfamily [IPR038023]", "VKOR domain superfamily [IPR038354]", "VPS9 domain superfamily [IPR037191]", "Vacuolar ATP synthase subunit C superfamily [IPR036132]", "Vacuolar protein sorting-associated protein 33, domain 3b [IPR043155]", "Vacuolar protein sorting-associated protein 35, C-terminal [IPR042491]", "Vacuolar protein sorting-associated protein IST1-like [IPR042277]", "Valyl-tRNA synthetase, tRNA-binding arm superfamily [IPR037118]", "Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain [IPR009008]", "Vanillyl-alcohol oxidase, C-terminal subdomain 2 [IPR016171]", "Vitamin B12-dependent methionine synthase, activation domain superfamily [IPR037010]", "Vps53, C-terminal domain superfamily [IPR038260]", "Vta1/Callose synthase, N-terminal domain superfamily [IPR023175]", "WD40-repeat-containing domain superfamily [IPR036322]", "WD40/YVTN repeat-like-containing domain superfamily [IPR015943]", "WGR domain superfamily [IPR036930]", "WIBG, N-terminal domain superfamily [IPR036348]", "WW domain superfamily [IPR036020]", "WWE domain superfamily [IPR037197]", "Winged helix DNA-binding domain superfamily [IPR036390]", "Winged helix-like DNA-binding domain superfamily [IPR036388]", "XPC-binding domain superfamily [IPR036353]", "YEATS superfamily [IPR038704]", "YebC-like [IPR029072]", "YjeF N-terminal domain superfamily [IPR036652]", "YqgF/RNase H-like domain superfamily [IPR037027]", "ZPR1, A/B domain [IPR042451]", "ZPR1, zinc finger domain [IPR042452]", "Zinc finger C2H2 superfamily [IPR036236]", "Zinc finger, C2H2C-type superfamily [IPR036060]", "Zinc finger, CCCH-type superfamily [IPR036855]", "Zinc finger, CCHC-type superfamily [IPR036875]", "Zinc finger, FYVE/PHD-type [IPR011011]", "Zinc finger, NHR/GATA-type [IPR013088]", "Zinc finger, PARP-type superfamily [IPR036957]", "Zinc finger, RING/FYVE/PHD-type [IPR013083]", "Zinc finger, RanBP2-type superfamily [IPR036443]", "Zinc finger, Sec23/Sec24-type superfamily [IPR036174]", "Zinc finger, ZZ-type superfamily [IPR043145]", "Zinc-binding ribosomal protein [IPR011332]", "dUTPase-like superfamily [IPR036157]", "eRF1, domain 1 [IPR024049]", "eRF1, domain 2 superfamily [IPR042226]", "mRNA decapping protein 2, Box A domain superfamily [IPR036189]", "p53-like tetramerisation domain superfamily [IPR036674]", "p53-like transcription factor, DNA-binding [IPR008967]", "p53/RUNT-type transcription factor, DNA-binding domain superfamily [IPR012346]", "rRNA adenine dimethylase-like, C-terminal [IPR023165]", "ssDNA-binding transcriptional regulator [IPR009044]", "tRNA (guanine-N1-)-methyltransferase, N-terminal [IPR029026]", "tRNA methyltransferase TRM10-type domain superfamily [IPR038459]", "tRNA methyltransferase, Trm1, C-terminal [IPR042296]", "tRNA modification GTPase MnmE domain 2 [IPR027368]", "tRNA-splicing ligase RtcB-like superfamily [IPR036025]", "tRNAHis guanylyltransferase Thg1 superfamily [IPR038469]", "von Willebrand factor A-like domain superfamily [IPR036465]"], "available_proteins": ["AAAS", "AACS", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABHD10", "ABHD12", "ABHD6", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ADA", "ADAM17", "ADAM9", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP13", "AKAP17A", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG5", "ALKBH5", "ALYREF", "AMPD2", "ANAPC1", "ANAPC2", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APBB1", "APC", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOBEC3C", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID2", "ARIH1", "ARL1", "ARL10", "ARL2", "ARL3", "ARL8B", "ARMC1", "ARMC10", "ARMC6", "ARMC8", "ARMCX3", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARVCF", "ASCC2", "ASCC3", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG4B", "ATIC", "ATL2", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5H", "ATP5O", "ATP6", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP6V1H", "ATPAF2", "ATRX", "ATXN10", "AURKB", "BABAM1", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAP18", "BAX", "BAZ1A", "BAZ1B", "BAZ2A", "BCAS3", "BCAT2", "BCL2L13", "BCOR", "BCS1L", "BDH2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BOLA2*", "BOP1", "BPTF", "BRCA1", "BRD2", "BRD3", "BRD4", "BRD7", "BRD8", "BROX", "BSG", "BTF3", "BTRC", "BUB1B", "BUB3", "BUD23", "BZW1", "BZW2", "C19orf47", "C1QBP", "C2CD2L", "C2CD5", "CAB39", "CACYBP", "CAD", "CADM1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN7", "CAPNS1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2AP", "CD2BP2", "CD47", "CDC20", "CDC23", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC5L", "CDC6", "CDC73", "CDH2", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CDKAL1", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPV", "CEP170", "CERS2", "CETN2", "CFL1", "CFL2", "CHAC2", "CHAF1B", "CHAMP1", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHORDC1", "CHP1", "CHRAC1", "CHTF18", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CIZ1", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLSTN3", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNN2", "CNN3", "CNNM4", "CNOT1", "CNOT10", "CNOT2", "CNOT7", "CNOT9", "CNP", "COA7", "COLEC12", "COLGALT1", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPZ1", "COQ8A", "COQ8B", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CREG1", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CRYZL1", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTH", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CUTA", "CWC22", "CWF19L1", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYP20A1", "CYP51A1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCP1A", "DCP2", "DCPS", "DCTN1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDB1", "DDI2", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DECR1", "DENND4C", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHFR", "DHPS", "DHRS4", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLST", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB4", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPM1", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS3L", "DUSP12", "DUSP3", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC3", "EDC4", "EDF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFHD1", "EFL1", "EFTUD2", "EGFR", "EHD1", "EHD4", "EHHADH", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3B", "EIF3E", "EIF3G", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELMO2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENPP1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERH", "ERLIN1", "ERLIN2", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC6", "EXOC7", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EYA4", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAHD2A", "FAM120A", "FAM120B", "FAM129B", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FBL", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FH", "FHOD1", "FKBP10", "FKBP14", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNBP1L", "FNBP4", "FNDC3A", "FOXK1", "FOXK2", "FOXRED1", "FSCN1", "FSTL1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCDH", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GGH", "GGPS1", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLDC", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA13", "GNAI2", "GNAI3", "GNB1L", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GNS", "GOLPH3", "GOLPH3L", "GOPC", "GORASP2", "GOT1", "GOT2", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPRASP2", "GPS1", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GUSB", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGFL2", "HDHD2", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIRA", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HMBS", "HMCES", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGXB4", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK2", "HOXD13", "HP1BP3", "HPRT1", "HPSE", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDE", "IDI1", "IFIT5", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPDH2", "INF2", "INTS1", "INTS11", "INTS12", "INTS14", "INTS4", "INTS7", "INTS9", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRS4", "ISOC1", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "IVD", "IWS1", "JUP", "KARS", "KAT7", "KCTD12", "KCTD5", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDM5A", "KDSR", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1468", "KIF11", "KIF14", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRR1", "KYAT3", "L2HGDH", "LACTB", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LRBA", "LRCH2", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC57", "LRRC59", "LRRC8C", "LRSAM1", "LRWD1", "LSG1", "LSM14B", "LSM2", "LSM3", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LYAR", "LYN", "LYPLA1", "LZIC", "MACF1", "MAD2L1", "MAGED1", "MAGED2", "MAGT1", "MAN1A1", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP2K1", "MAP2K4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARK2", "MARK3", "MARS", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MCAM", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED16", "MED21", "MED25", "MEPCE", "METAP1", "METTL13", "METTL15", "MFN1", "MFSD10", "MFSD3", "MFSD5", "MGEA5", "MGME1", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MIF", "MINDY3", "MINPP1", "MIOS", "MIPEP", "MKI67", "MKRN2", "MMAB", "MMS19", "MOB4", "MOGS", "MON2", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPDZ", "MPG", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPRIP", "MPST", "MRC2", "MRE11", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL38", "MRPL39", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL55", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS25", "MRPS27", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTM1", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MTX3", "MUT", "MYBBP1A", "MYCBP2", "MYEF2", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO6", "NAA10", "NAA15", "NAA40", "NAA50", "NACC1", "NADK2", "NAE1", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCBP1", "NCBP3", "NCDN", "NCK1", "NCK2", "NCKIPSD", "NCL", "NCOA5", "NDRG3", "NDUFA10", "NDUFA9", "NDUFAF3", "NDUFAF7", "NDUFS1", "NDUFS3", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4", "NEDD4L", "NEK9", "NELFE", "NENF", "NEU1", "NF2", "NFRKB", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIPSNAP3A", "NISCH", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NME1", "NME2", "NME3", "NME7", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL8", "NOL9", "NOM1", "NONO", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NOVA2", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NRBP1", "NRDC", "NRP1", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDCD2", "NUDT1", "NUDT12", "NUDT16L1", "NUDT21", "NUDT5", "NUF2", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP98", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCLN", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC5", "OS9", "OSBP", "OSBPL11", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OXSR1", "P3H1", "P3H3", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAIP1", "PAK1IP1", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PAOX", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PATJ", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH19", "PCID2", "PCK2", "PCMT1", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDP1", "PDPR", "PDS5A", "PDS5B", "PDSS2", "PDXK", "PDZD11", "PEBP1", "PECR", "PEF1", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF14", "PHF3", "PHF6", "PHF8", "PHGDH", "PHIP", "PHRF1", "PI4KA", "PI4KB", "PICALM", "PIGL", "PIK3C2A", "PIK3R4", "PIN1", "PIP4K2C", "PIR", "PITHD1", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PKP2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNO1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3F", "POLRMT", "POMGNT2", "PON2", "POP4", "POR", "PPA1", "PPA2", "PPAT", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP1R9B", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRKAA1", "PRKACA", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG2", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PWP1", "PWP2", "PYCR1", "PYCR2", "PYCR3", "PYM1", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB3B", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABGAP1", "RABGGTA", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBFOX2", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "RECQL5", "REL", "REPS1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RICTOR", "RIDA", "RIF1", "RINT1", "RMDN1", "RMDN3", "RNASEH2A", "RNASET2", "RNF114", "RNF14", "RNF20", "RNF219", "RNF40", "RNH1", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPP25L", "RPP30", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS8", "RPS9", "RPSA", "RPTOR", "RREB1", "RRM1", "RRM2", "RRP12", "RRP8", "RRP9", "RSF1", "RSL1D1", "RSU1", "RTCA", "RTCB", "RTN4IP1", "RUFY1", "RUVBL1", "RUVBL2", "RXRB", "S100A10", "S100A11", "S100A13", "SAAL1", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAP18", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART3", "SASS6", "SATB2", "SBDS", "SBNO1", "SCAF11", "SCAF4", "SCCPDH", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEH1L", "SEL1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT8", "SEPT9", "SERAC1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3B1", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGPL1", "SGTA", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHC1", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SIN3A", "SIN3B", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC30A7", "SLC3A2", "SLC4A1AP", "SLC4A7", "SLC5A6", "SLC6A15", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLMAP", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG9", "SMU1", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPECC1", "SPECC1L", "SPEN", "SPNS1", "SPOUT1", "SPR", "SPRYD4", "SPRYD7", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRBD1", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "STAG1", "STAG2", "STAM", "STARD3", "STARD7", "STAT1", "STIP1", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STUB1", "STX10", "STX12", "STX3", "STX5", "STX6", "STX7", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUMO2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNJ2BP", "TAB1", "TACO1", "TAF15", "TAF4", "TAGLN2", "TALDO1", "TAOK3", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL2", "TBL3", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCF25", "TCP1", "TDP2", "TDRKH", "TECR", "TELO2", "TENM3", "TERF2IP", "TEX10", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFRC", "THADA", "THG1L", "THOC1", "THOC3", "THOC6", "THOP1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMM13", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TIMM9", "TJP1", "TJP2", "TK1", "TKT", "TLN1", "TMA16", "TMED1", "TMED2", "TMED5", "TMEM14C", "TMLHE", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNPO1", "TNPO3", "TOE1", "TOM1", "TOMM20", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOPBP1", "TOR1A", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TOX4", "TP53", "TP53BP1", "TP53BP2", "TPBG", "TPD52L2", "TPI1", "TPM4", "TPP1", "TPP2", "TPT1", "TRA2A", "TRA2B", "TRAP1", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRIT1", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPO", "TSPYL1", "TST", "TSTA3", "TTC1", "TTC19", "TTC21B", "TTC26", "TTC27", "TTC37", "TTC38", "TTC4", "TTC5", "TTF2", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWNK", "TXNDC12", "TXNDC16", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UACA", "UAP1", "UBA1", "UBA2", "UBA5", "UBA6", "UBAC1", "UBAP2", "UBAP2L", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBL5", "UBLCP1", "UBP1", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFD1", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119B", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "UROD", "USO1", "USP1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP28", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "UXS1", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VASP", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIRMA", "VKORC1L1", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS51", "VPS53", "VRK1", "VRK2", "VTA1", "WAPL", "WARS", "WARS2", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR36", "WDR41", "WDR43", "WDR45B", "WDR46", "WDR5", "WDR6", "WDR61", "WDR73", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIZ", "WNK1", "WNK3", "WRAP53", "WRAP73", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "YARS", "YARS2", "YBX1", "YEATS2", "YEATS4", "YES1", "YKT6", "YLPM1", "YME1L1", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H15", "ZC3H18", "ZC3H7B", "ZC3HAV1", "ZCCHC11", "ZCCHC3", "ZCRB1", "ZFR", "ZFYVE16", "ZMYND8", "ZNF280C", "ZNF281", "ZNF512", "ZNF512B", "ZNF622", "ZNF638", "ZNF687", "ZPR1", "ZRANB2", "ZZEF1"], "leading_proteins": ["ACTN1", "ACTN2", "ADD1", "ADD3", "AFDN", "AFG3L2", "AIFM1", "AIP", "AKT1", "AKT2", "ALDH1B1", "ALDH3A2", "ANAPC5", "ANAPC7", "ANKLE2", "APEH", "ARFIP2", "ASCC2", "ATP13A1", "ATP1A1", "ATP1B1", "ATP2A2", "ATP2C1", "BAG6", "BAIAP2", "BCL2L13", "CALM3", "CALU", "CAMK2G", "CARM1", "CASK", "CCNA2", "CCNB2", "CCT3", "CERS2", "CETN2", "CLNS1A", "CLUH", "CNNM4", "COA7", "COMT", "COPG2", "COPS2", "CPT2", "CRTAP", "CTNNAL1", "CYB5B", "CYB5D2", "CYP51A1", "DCUN1D4", "DENND4C", "DERL2", "DHCR24", "DIAPH3", "DLG1", "DNAJA2", "DNAJC1", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM2", "DVL2", "EIF3L", "EMC2", "ENDOD1", "ERAP1", "ERBIN", "EWSR1", "EXOC6", "EXOSC2", "EZR", "FKBP10", "FKBP14", "FKBP4", "FKBP7", "FKBP9", "FLAD1", "FUBP1", "FUBP3", "FUS", "FXR2", "G3BP2", "GALNT1", "GALNT2", "GAPVD1", "GET4", "GGCX", "GLT8D1", "GMPPB", "GOLPH3L", "GOPC", "GPD2", "GSTO1", "GTF2B", "GYG1", "HDHD3", "HDHD5", "HMOX2", "HNRNPK", "HTRA2", "IGF2BP2", "INF2", "KHDRBS1", "KHDRBS3", "KHSRP", "KIF14", "KIF1B", "KIF5B", "KIF7", "KIFBP", "KLC2", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "LEMD3", "LMNA", "LMNB2", "LRPPRC", "MAN1A1", "MAPRE2", "MCL1", "METTL15", "MGEA5", "MICU1", "MICU2", "MINDY3", "MOGS", "MORF4L1", "MPP1", "MPP2", "MPP5", "MPP6", "MRC2", "MSH2", "MSH6", "MSTO1", "MTX1", "MYH10", "MYH14", "MYH9", "NAA15", "NAP1L4", "NENF", "NISCH", "NLN", "NNT", "NOVA2", "NPEPPS", "NSUN2", "NSUN5", "NT5C3B", "NTMT1", "NUB1", "NUCB2", "OGT", "P3H1", "P3H3", "P3H4", "P4HA1", "P4HA2", "PABPC1", "PAFAH1B2", "PAK2", "PANK4", "PCYOX1", "PEX5", "PFDN6", "PIR", "PITRM1", "PNPLA6", "PPAT", "PPP4R3A", "PRMT3", "PRMT9", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMD11", "PSMD3", "PSME1", "PSME3", "PTCD3", "QKI", "RABGAP1", "RAPGEF2", "RBM10", "RCN2", "REPS1", "RMDN1", "RMDN3", "RNF14", "ROCK2", "RPS3", "SEL1L", "SET", "SIN3B", "SLC25A10", "SLC25A20", "SLC25A26", "SLC25A32", "SMC3", "SNX2", "SNX27", "SNX5", "SNX6", "SPTAN1", "SPTBN1", "SPTBN2", "SQSTM1", "STARD3", "STK4", "STX3", "STX6", "STXBP4", "SYNJ2BP", "TAF15", "TCF25", "TDRKH", "TENM3", "THOP1", "TIMM8A", "TIMM8B", "TIMM9", "TJP2", "TLN1", "TMED2", "TMED5", "TPP2", "TSNAX", "TTC19", "TTC21B", "TTC26", "TTC27", "TTC37", "TTC4", "TUBB", "TUBB2A", "TUBB3", "TUBB4B", "TUBB6", "UBE2Q1", "UBQLN1", "UBXN1", "UGCG", "UQCRC2", "USP15", "USP28", "USP47", "VCL", "VDAC1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAZ", "ZADH2"]} \ No newline at end of file diff --git a/interpro_ptm/advanced/idx2term.json b/interpro_ptm/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_ptm/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_ptm/basic/idx2term.json b/interpro_ptm/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_ptm/basic/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_ptm/consensus.joblib b/interpro_ptm/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..2b007b7e04f9ba4ed952ff90a06888a7a6ebfaed --- /dev/null +++ b/interpro_ptm/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3266605a6a304282363e10d495ee250e3251f80e111203475f743b05c412881d +size 75082 diff --git a/interpro_ptm/df_merge.tsv b/interpro_ptm/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..88ae42ff5fb775c883b390f007d91b3333d6deb5 --- /dev/null +++ b/interpro_ptm/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +P-type ATPase, phosphorylation site [IPR018303] 3 6 2.0877925802438866 0.0368165491671925 2.941747572815534 6.145631067961165 0.9567723497044874 0.2732808833570771 1.8358630293390923 1.459204245106796 1.2102525517005158 0.2943240638910574 0.237888308904226 1.0 0.191600110602388 0.0990342687178565 0.2914565107291916 diff --git a/interpro_ptm/metrics.json b/interpro_ptm/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..a1aee5b12c93618504e061b9a624c5b6bb786677 --- /dev/null +++ b/interpro_ptm/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3381, + "annotations_size": 5, + "title": "Average number of proteins per term", + "value": 2.6 +} \ No newline at end of file diff --git a/interpro_ptm/paths.json b/interpro_ptm/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..178c13ec392f27ba4dc87aaed9110e336da5aa91 --- /dev/null +++ b/interpro_ptm/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_ptm/fragment/C317/C317_val_log2fc"} \ No newline at end of file diff --git a/interpro_ptm/result.tsv b/interpro_ptm/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..59e68345372357d187e2fec539009751705d1220 --- /dev/null +++ b/interpro_ptm/result.tsv @@ -0,0 +1,2 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +P-type ATPase, phosphorylation site [IPR018303] 0.7874198459158005 2.0877925802438866 0.0368165491671925 0.1710180771848113 0.1840827458359628 6 P16615,Q9HD20,P05023 3 diff --git a/interpro_ptm/selections.json b/interpro_ptm/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..3c7a43fb5c5cfdb25e6568e7d3e56936f3315d5e --- /dev/null +++ b/interpro_ptm/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["EGF-type aspartate/asparagine hydroxylation site [IPR000152]", "P-type ATPase, phosphorylation site [IPR018303]", "Phosphopantetheine attachment site [IPR006162]", "Rapamycin-insensitive companion of mTOR, phosphorylation-site [IPR029259]", "Translation elongation factor, IF5A, hypusine site [IPR019769]"], "available_proteins": ["ATP11C", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2C1", "EIF5A", "FASN", "LDLR", "LRP1", "LRP2", "RICTOR", "SLIT2"], "leading_proteins": ["ATP13A1", "ATP1A1", "ATP2A2"]} \ No newline at end of file diff --git a/interpro_repeat/advanced/idx2term.json b/interpro_repeat/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_repeat/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_repeat/basic/idx2term.json b/interpro_repeat/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..06e546ca931b75c14d3d475aeed40509536c198e --- /dev/null +++ b/interpro_repeat/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Tetratricopeptide repeat [IPR019734]", "1": "Spectrin repeat [IPR002017]", "2": "Spectrin/alpha-actinin [IPR018159]"} \ No newline at end of file diff --git a/interpro_repeat/basic/plot_0.png b/interpro_repeat/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..e7ea1e4137897c57047128b5c7b47d127fd91a4a --- /dev/null +++ b/interpro_repeat/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:94f41c6a46a9f6c90bc94980d1f2043970c1d53bc14e76743d5c1fa571e9740a +size 148451 diff --git a/interpro_repeat/basic/plot_1.png b/interpro_repeat/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..687d24c32128dac6203b5441d7489f22d4309491 --- /dev/null +++ b/interpro_repeat/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e5b3575441181e47e8db041022e0a4eb265bd130dd907b430606fe9b5a4a12be +size 121128 diff --git a/interpro_repeat/basic/plot_2.png b/interpro_repeat/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..c0eec794367b017f060069ef317393ab2586f4b1 --- /dev/null +++ b/interpro_repeat/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1760eb52016274118018fc3a9c6622b63a355569ab8e57a57060490961abd35b +size 138387 diff --git a/interpro_repeat/consensus.joblib b/interpro_repeat/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..c55a03b0910a2b51b4ccc6ded52a1a52c37e7042 --- /dev/null +++ b/interpro_repeat/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:974ce453ca04a06825460265c58733e18fbab718f30b6ed5b49ede51fe9e3a3f +size 76980 diff --git a/interpro_repeat/df_merge.tsv b/interpro_repeat/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..469984cf25d2abf479a962cadb60fc5504c5f0ec --- /dev/null +++ b/interpro_repeat/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Mitochondrial substrate/solute carrier [IPR018108] 4 21 2.2912139971222376 0.0219510398088893 9.148058252427184 20.71359223300971 2.0411027534642088 0.1411881998864352 5.368907349966936 1.8276489510009888 1.309103123363054 0.2428184236965967 0.0111023154777706 0.1675604235637086 0.0513963234576887 0.064307133891248 0.0359117122080593 diff --git a/interpro_repeat/metrics.json b/interpro_repeat/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..701141a41ab5d587e4e2fca988149306b9a62af9 --- /dev/null +++ b/interpro_repeat/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3381, + "annotations_size": 82, + "title": "Average number of proteins per term", + "value": 5.548780487804878 +} \ No newline at end of file diff --git a/interpro_repeat/paths.json b/interpro_repeat/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..2adb22fa8baab0250560fa9185c82bdc7ae0353a --- /dev/null +++ b/interpro_repeat/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_repeat/fragment/C317/C317_val_log2fc"} \ No newline at end of file diff --git a/interpro_repeat/result.tsv b/interpro_repeat/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..29ca4b2945c30114f646c62c7bcf2cedd89906e2 --- /dev/null +++ b/interpro_repeat/result.tsv @@ -0,0 +1,13 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mitochondrial substrate/solute carrier [IPR018108] 0.5792617613881876 2.2912139971222376 0.0219510398088893 0.8379799182043519 0.3585417682471708 21 Q9UBX3,O43772,Q9H2D1,Q70HW3 4 +Sel1-like repeat [IPR006597] 0.8529150636282937 1.03280898422577 0.3016932984911418 0.9999999999998372 0.6238531656917345 2 Q9UBV2 1 +Tetratricopeptide repeat [IPR019734] 0.39167523880232 0.874967056660983 0.3815918307634511 1.0 0.695345113835622 51 P13674,Q9NSK0,Q9H0B6,P49321,P50542,O00170,Q9UJX3,O15294,P31948,Q13217,O15460,Q9UGR2,Q9BXJ9,Q15006,Q6PGP7,O43765,Q7Z4L5,Q6P3X3,Q6DKK2,O95801,A0AVF1,Q02790,Q9UJX4,Q6P2P2,Q07866 25 +Spectrin repeat [IPR002017] 0.4715485150257904 0.841261562890263 0.400201418669547 1.0 0.6982237517213374 10 P35609,Q13813,O43707,P12814,Q8WXH0,Q01082 6 +HEAT repeat [IPR000357] 0.499832844697509 0.7671578050847271 0.4429876968209201 1.0 0.7567706487357385 6 O00410,P30154 2 +Spectrin/alpha-actinin [IPR018159] 0.4262610246728283 0.7329776994836725 0.4635720309229851 1.0 0.7757736027690773 12 P35609,Q13813,O43707,P12814,Q8WXH0,Q01082 6 +Pentatricopeptide repeat [IPR002885] 0.4643272681023012 0.378401284999867 0.7051325137462805 1.0 0.984392088175938 4 P42704 1 +Atypical Arm repeat [IPR032413] 0.3729265402843499 0.1896812876005828 0.8495588849304507 1.0 1.0 5 P52292,O00505,O60684,O00629 4 +Tetratricopeptide repeat 2 [IPR013105] 0.3626155040653144 0.1630565958578031 0.8704738738360118 1.0 1.0 5 Q6P3X3,Q02790 2 +HEAT, type 2 [IPR021133] 0.29204609020642 0.0619028968723228 0.9506401605540604 1.0 1.0 12 Q9BU89 1 +Paired amphipathic helix [IPR003822] 0.4664101805267909 0.0575543175853827 0.9541036386009228 1.0 1.0 2 O75182 1 +Leucine rich repeat 4 [IPR025875] 0.3291888691533419 0.0367704486630524 0.970668036658062 1.0 1.0 3 Q13045,Q9UFC0 2 diff --git a/interpro_repeat/selections.json b/interpro_repeat/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..5ccfbd506b6ab6445464f7bbfe6cdee19106225e --- /dev/null +++ b/interpro_repeat/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Adenomatous polyposis coli (APC) repeat [IPR041257]", "Adenomatous polyposis coli protein repeat [IPR009223]", "Adenomatous polyposis coli protein, 15 residue repeat [IPR009240]", "Ankyrin repeat [IPR002110]", "Annexin repeat [IPR018502]", "Armadillo [IPR000225]", "Atypical Arm repeat [IPR032413]", "BIR repeat [IPR001370]", "Beta-propeller repeat TECPR [IPR006624]", "BspA type Leucine rich repeat region [IPR026906]", "Calponin repeat [IPR000557]", "Cation-independent mannose-6-phosphate receptor repeat [IPR000479]", "Chromosome region maintenance repeat [IPR041123]", "Clathrin, heavy chain, propeller repeat [IPR022365]", "Clathrin, heavy chain/VPS, 7-fold repeat [IPR000547]", "Collagen triple helix repeat [IPR008160]", "Cysteine-rich Golgi apparatus protein 1 repeat [IPR001893]", "Cysteine-rich Golgi apparatus protein 1 repeat, eukaryote [IPR017873]", "Exportin-1, repeat 2 [IPR041235]", "Exportin-1, repeat 3 [IPR040485]", "Filamin/ABP280 repeat [IPR001298]", "Filamin/ABP280 repeat-like [IPR017868]", "Furin-like repeat [IPR006212]", "G-protein beta WD-40 repeat [IPR020472]", "GTF2I-like repeat [IPR004212]", "HAT (Half-A-TPR) repeat [IPR003107]", "HEAT repeat [IPR000357]", "HEAT repeat associated with sister chromatid cohesion protein [IPR026003]", "HEAT, type 2 [IPR021133]", "HUWE1/Rev1, ubiquitin binding region [IPR025527]", "Hexapeptide repeat [IPR001451]", "Hs1/Cortactin [IPR003134]", "Huntingtin, middle-repeat [IPR024613]", "Importin repeat 4 [IPR041653]", "Importin repeat 6 [IPR041389]", "Importin repeat [IPR040928]", "KI67R [IPR012568]", "Kelch repeat type 1 [IPR006652]", "Kinesin light chain repeat [IPR015792]", "LDLR class B repeat [IPR000033]", "Leucine rich repeat 4 [IPR025875]", "Leucine-rich repeat [IPR001611]", "Leucine-rich repeat, cysteine-containing subtype [IPR006553]", "Leucine-rich repeat, typical subtype [IPR003591]", "Low-density lipoprotein (LDL) receptor class A repeat [IPR002172]", "MORN motif [IPR003409]", "Mbt repeat [IPR004092]", "Microtubule associated protein, tubulin-binding repeat [IPR001084]", "Mitochondrial substrate/solute carrier [IPR018108]", "NHL repeat [IPR001258]", "Nebulin repeat [IPR000900]", "Neuraxin/MAP1B repeat [IPR000102]", "P120R repeat [IPR012586]", "PBS lyase HEAT-like repeat [IPR004155]", "Paired amphipathic helix [IPR003822]", "Parallel beta-helix repeat [IPR006626]", "Pentatricopeptide repeat [IPR002885]", "Plectin repeat [IPR001101]", "Plexin repeat [IPR002165]", "Proteasome/cyclosome repeat [IPR002015]", "Protein of unknown function DM15 [IPR006607]", "Protein prenyltransferase, alpha subunit [IPR002088]", "Proteinase inhibitor I27, calpastatin [IPR001259]", "Pumilio RNA-binding repeat [IPR001313]", "Putative TPR-like repeat [IPR031545]", "Pyrrolo-quinoline quinone repeat [IPR002372]", "RNA helicase p68 repeat [IPR012587]", "RNA polymerase II, heptapeptide repeat, eukaryotic [IPR000684]", "Regulator of chromosome condensation, RCC1 [IPR000408]", "Ribonuclease inhibitor, leucine rich repeat cap [IPR041302]", "SAMP [IPR009224]", "Sel1-like repeat [IPR006597]", "Spectrin repeat [IPR002017]", "Spectrin/alpha-actinin [IPR018159]", "Tetratricopeptide repeat 1 [IPR001440]", "Tetratricopeptide repeat 2 [IPR013105]", "Tetratricopeptide repeat [IPR019734]", "Vesicle tethering protein p115, armadillo tether-repeat [IPR041209]", "WD40 repeat [IPR001680]", "Wolframin, Sel1-like repeat [IPR045458]", "YD repeat [IPR006530]", "Zinc finger, C2H2C-type [IPR002515]"], "available_proteins": ["AAAS", "ACTN1", "ACTN2", "ACTN4", "AIP", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKRD17", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1B1", "AP2B1", "APC", "ARMC1", "ARMC6", "ARMC8", "ARMCX3", "ARPC1A", "ARVCF", "ASPH", "BCOR", "BIRC6", "BOP1", "BTRC", "BUB3", "CAST", "CDC20", "CDC23", "CDC27", "CDC40", "CHAF1B", "CKAP5", "CLASP1", "CLPB", "CLTC", "CNN2", "CNN3", "CNOT10", "COA7", "COLEC12", "COPA", "COPB2", "CORO1B", "CORO1C", "CORO7", "CRNKL1", "CSTF1", "CSTF3", "CTNNB1", "CTNND1", "CTR9", "CTTN", "DCAF13", "DCAF7", "DDX5", "DNAAF5", "DNAJC3", "DNAJC7", "DOHH", "DSP", "DST", "DYNC1I2", "EDC4", "EGFR", "EHMT2", "EIF2B5", "EIF3I", "ELP2", "EMC1", "EMC2", "EML4", "EPPK1", "ERBIN", "FKBP4", "FKBP5", "FKBP8", "FLII", "FLNA", "FLNB", "FLNC", "GCN1", "GEMIN5", "GLG1", "GLS", "GMPPA", "GMPPB", "GNB1L", "GRWD1", "GTF2I", "GTF3C3", "HCFC1", "HECTD1", "HERC2", "HIRA", "HTT", "HUWE1", "IFIT5", "IGF2R", "ILK", "INTS4", "IPO4", "IPO5", "JUP", "KAT7", "KDELC2", "KDM2A", "KEAP1", "KIAA1468", "KLC1", "KLC2", "KLC4", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "LARP1", "LASP1", "LDLR", "LLGL1", "LRBA", "LRCH2", "LRP1", "LRP2", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC57", "LRRC59", "LRRC8C", "LRSAM1", "LRWD1", "MACF1", "MAP1B", "MAP4", "MAU2", "MED16", "MIOS", "MKI67", "MPHOSPH8", "MRPS27", "MTCH1", "MTCH2", "MYCBP2", "NAA15", "NASP", "NEK9", "NHLRC2", "NIPBL", "NISCH", "NLE1", "NLRX1", "NOL10", "NOP2", "NOP9", "NUDT12", "NUP214", "NUP37", "NUP43", "NXF1", "OGT", "P4HA1", "P4HA2", "PAFAH1B1", "PAK1IP1", "PDCD11", "PEX5", "PHIP", "PIK3R4", "PKP2", "PLAA", "PLEC", "PLRG1", "PLXNB2", "POLR2A", "PPID", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP5C", "PREB", "PRKCSH", "PRMT9", "PRPF19", "PRPF4", "PRPF6", "PSMD1", "PSMD10", "PSMD2", "PTCD1", "PTCD3", "PUM1", "PUM3", "PWP1", "PWP2", "RABGGTA", "RACK1", "RAE1", "RAI14", 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0.0481387300298592 0.1143079274466006 0.078632686100437 0.0028520636453917 4.219109993755922e-08 +Calcium ion import 6 13 2.547687951826181 0.0108439421214054 4.516990291262136 12.686893203883496 1.0417029373125424 0.2391249176108038 2.3196506830054986 1.9148178088324157 1.3383409214307818 0.27915846054651 1.0 1.0 1.0 0.001886473535207 0.0018029983207632 +Metal ion transport 34 109 2.540997436532681 0.0110536729957919 24.868932038834952 99.21116504854368 0.6600358663497399 0.5322554902435589 9.162889792248723 11.473971032908404 1.1670714049066973 0.3920241658733104 0.8051576924172369 0.5023005139274972 0.6553745636256861 0.0449071836479414 0.0033085700644148 +Protein transmembrane transport 8 28 2.478103994893873 0.0132082641162898 8.992718446601941 25.191747572815533 1.6893060623430327 0.189108476986505 4.473486660459625 2.7693940759543416 1.4682653164365471 0.2783169275392022 0.0004580855833987 0.000115947693888 0.0001474440444245 0.0002745543568096 0.0002030463281523 +Intracellular protein transmembrane transport 7 24 2.47636507279294 0.0132727782640418 7.233009708737864 21.9004854368932 1.450039081018812 0.2247265328975946 3.8281123729210935 2.4627910122818513 1.3220665029303609 0.2876555154826584 0.0021752551470332 0.0012844156650938 0.0008840144918394 0.0007167071983955 0.0013172325096431 +Chloride transport 6 12 2.461850333864286 0.0138222332483575 4.33252427184466 12.12621359223301 1.0302584084066435 0.2341882174183942 2.3624510960969567 2.26059366569241 1.2797232968088257 0.2563105728143979 0.0615154966441759 0.1471951297158956 0.0398064357050217 0.1911341037783432 0.0206839034685982 +Negative regulation of calcium ion transmembrane transport 4 10 2.453177515027728 0.0141600441373388 2.1067961165048543 7.601941747572815 0.9433101814663925 0.3101119054926485 1.594362771690279 1.170758660555987 1.028728108691548 0.2750664841729511 0.2090990449320472 0.0875404472016038 0.1677870330809631 0.0009927961558234 0.0017743753624758 +Negative regulation of calcium ion transport 4 10 2.453177515027728 0.0141600441373388 2.378640776699029 8.815533980582524 0.865801675063994 0.3348216966365627 1.767376998119782 1.5264501163101216 0.996781239251156 0.2731835761958332 0.3096765085512921 0.134742527043449 0.2518545844225215 0.0056932223374956 0.0139902560164694 +Purine ribonucleoside metabolic process 2 8 2.44019115899993 0.0146794918266708 2.063106796116505 7.834951456310679 1.2047777662844132 0.2574288772305114 1.199068432200366 0.6246876870736083 0.9870596763535292 0.2611531847589775 0.0010788177062325 0.0786913117950012 0.0005309775927247 0.0075105395483816 0.0470360579614364 +Positive regulation of establishment of protein localization 29 100 2.433095095007028 0.0149703685900637 20.5 89.78398058252426 0.0167070661850674 0.8272206822927444 8.878494799396607 10.911134229509791 0.5083050654365172 0.2492803503219096 0.1225933742963436 0.0831918202589172 0.150544819415209 0.0776265475531858 0.0039311133076858 +Ion homeostasis 31 108 2.419265883803624 0.0155518680762896 28.021844660194176 105.69174757281552 0.8349951537384392 0.4299135801564597 10.40966729997928 11.411952082971936 1.4722934854811005 0.3963893325418664 0.0512902142624473 0.0745157705462292 0.0144227917277509 0.0156551953018052 0.0114570159572874 +Calcium import into the mitochondrion 4 6 2.418539076563423 0.0155829717347619 2.4563106796116503 6.04126213592233 0.8091317576129835 0.2214807715451704 1.7082137325011066 1.2010296388602073 1.3762222767333927 0.2421218388926935 1.0 1.0 1.0 0.0026581093268102 0.000160552482799 +Myelin maintenance 3 6 2.407705539561252 0.0160531229964424 1.2451456310679612 3.8737864077669903 0.335236480366939 0.532980188163816 1.10409684048118 1.2879547393790816 0.9584033763618772 0.3264942299393454 0.1482449280840973 0.0607401038440192 0.1180585699575878 0.0033939033653995 0.0028040242445346 +Antigen processing and presentation of endogenous antigen 2 8 2.4037886898100225 0.0162261495536655 2.6529126213592233 6.463592233009709 1.0779744166035472 0.2832041157954688 1.4492771087670022 1.3990755299770097 1.00991421519493 0.2818848392729987 0.0141047644752725 0.0697581245313758 0.1349531130589082 0.050241067872642 0.0338099842169397 +Antigen processing and presentation of endogenous peptide antigen 2 8 2.4037886898100225 0.0162261495536655 2.638349514563106 6.390776699029126 1.097011591019633 0.2766562869747734 1.460743657586565 1.3760123823390067 1.0015631459591094 0.2785574288267012 0.0123221163543065 0.0652597674910206 0.1265462710440741 0.0442367692127036 0.0280386150660574 +Mitochondrial transmembrane transport 20 53 2.39230992935698 0.0167426975303988 19.070388349514563 50.63834951456311 1.9310146760091371 0.188342667216329 9.760351579527285 3.939196260509299 1.9786128158557912 0.3017981993827387 0.0005972533630971 0.0007162824744306 0.00132313066272 3.812521632033891e-05 1.2912647045240088e-05 +Retrograde vesicle mediated transport golgi to endoplasmic reticulum 7 30 2.3811204766382508 0.0172600659904507 7.771844660194175 26.825242718446603 1.1714448828781496 0.3436005361805324 3.811248488859092 3.450558374586287 1.1733172803389544 0.345676809182098 0.0025555008221064 0.0213158974187442 0.0010428679183072 0.00545325875553 0.0003749043951495 +Glial cell development 5 26 2.3737663646357685 0.0176076878969801 5.114077669902913 20.08495145631068 0.342527471970151 0.5482793913252476 2.6656928412824445 3.2664916525364203 0.9072377099594536 0.3081373734674846 0.0419634029481528 0.2624522374738631 0.1226746045160812 0.0041578852276634 0.0328483629407697 +Protein transmembrane import into intracellular organelle 4 15 2.3620824783734875 0.0181725986436873 4.951456310679611 13.45631067961165 1.503963012554726 0.1758225015375162 2.735521961789203 1.4944992929031071 1.2360761671845495 0.245991671368161 0.0518879113758937 0.0090330503435184 0.0334071197556988 0.0056932223374956 0.0139902560164694 +Peripheral nervous system development 4 15 2.357382698930341 0.0184042688339065 2.9757281553398056 11.519417475728156 0.6034295307069711 0.4690475043667866 1.8206990026194103 2.156973709389053 0.837829879270116 0.2915098257052096 0.0165305690462396 0.0188245552589776 0.0666692325567911 0.0040949780430722 0.0190396454378568 +Regulation of ph 5 22 2.328682215991124 0.0198759069337599 6.890776699029126 20.859223300970875 1.2151699598837196 0.2373503364294603 2.930458126920059 2.7746402510870145 1.4154672965603718 0.2873526492076106 0.0257105783879839 0.2220822570468345 0.0135419734012732 0.001554887013827 0.012512209523234 +Regulation of cellular ph 5 22 2.328682215991124 0.0198759069337599 6.885922330097087 20.844660194174757 1.215766922704761 0.2375185297794358 2.9319293283093293 2.765976649626597 1.4143296516981956 0.2875299337708636 0.0220060448298776 0.2107016729382093 0.0115248505447769 0.0011347755104788 0.0091015487948519 +Ensheathment of neurons 12 30 2.3173312188408475 0.0204856959475245 7.109223300970874 25.317961165048544 0.4295341143396002 0.5630321678871352 3.545161118750975 3.535996271146197 0.857834731365342 0.3150461050621543 0.0934317535567484 0.0667099047189351 0.2072288126229632 0.0055138461474184 0.01028970028679 +Ion transmembrane transport 47 165 2.316762629448064 0.0205166657936644 47.09466019417476 154.11893203883494 1.555073205784263 0.3634279635891347 19.61122797656 15.97124025754773 1.9676287128633565 0.411597796705808 0.024473235444499 0.0214509424446739 0.0313250751112007 0.0038097465911249 0.0008528745537794 +Response to food 2 6 2.306231443044124 0.0210977035326778 1.720873786407767 5.783980582524272 1.3281223897944048 0.1823213242558801 0.9790282548915298 0.8299231919143666 1.0823564620426191 0.211054619984942 0.1482449280840973 0.0607401038440192 0.1180585699575878 0.0033939033653995 0.0228394808772788 +Cation transmembrane transport 34 126 2.3001890887089447 0.0214375097265746 33.43446601941748 118.4004854368932 1.1701058025505957 0.4085228823574113 14.425169362008605 12.553856783980793 1.6663185381795875 0.4066910074955585 0.1752978975356144 0.0086344442231225 0.0681922680675891 0.0396256682608942 0.0089392883247684 +Protein import into mitochondrial matrix 2 9 2.290223771579328 0.0220083480854353 3.3276699029126213 9.03883495145631 1.4677455160780188 0.1396272549365287 1.9612536628062327 0.7162785445212654 1.2893924319512868 0.2212161399323651 0.0141047644752725 0.0022827689145391 0.0088504827764808 0.050241067872642 0.0338099842169397 +Negative regulation of ion transmembrane transporter activity 5 16 2.2759639791667605 0.0228481656239605 3.817961165048544 11.861650485436892 0.3764600221454999 0.5118077234396127 2.3889648646862596 1.939068236399221 0.964288359393085 0.3191649145735881 0.3430128009859742 0.151306852499084 0.2802926639431586 0.0489147892655661 0.0233089974379561 +Cytosolic calcium ion transport 9 25 2.2660650724958056 0.0234473993562442 6.567961165048544 23.944174757281555 0.4634706877593821 0.4616211122842976 3.323605294530572 2.8902732844456565 1.0331628024603872 0.3216839736311487 0.6510707013493795 0.3371313972628795 0.5614825641059915 0.0172426826928339 0.0081165871149163 +Mitochondrion organization 79 202 2.263548957458182 0.0236018702468505 56.45873786407767 188.26941747572815 1.5905300936136977 0.4100157441778524 20.15716756472138 18.40319032732565 2.034523716094369 0.4327537677377048 0.0002707247368782 5.040451155566826e-06 6.572095202764028e-05 0.0001494447070225 3.733314666616177e-09 +Schwann cell development 3 10 2.2541308965352123 0.0241879344823765 2.4150485436893203 7.487864077669903 0.0164677406559132 0.5754256017702141 1.6880697161478695 2.129849874141248 0.8900651354666074 0.3003336502630982 0.0318919308376235 0.1049896535105009 0.1993869387044997 0.0175758241055335 0.0236194052560011 +Ribonucleoside metabolic process 2 9 2.237763288082196 0.0252364956490755 2.1189320388349513 8.12621359223301 1.1914157696469383 0.2635896161542528 1.2648845164842024 0.7462477223524518 0.9827848183963048 0.2624193088278075 0.0030163941113643 0.1093006244161378 0.0015052123544451 0.0197332243190265 0.1093101132411038 +Plasma membrane organization 10 32 2.2278299904534484 0.025891854143347 7.099514563106796 28.24514563106796 0.6737258386983643 0.4958528160030953 3.5234718862626195 4.368421626063976 0.8695791931528731 0.3271220115282837 0.2616285001692507 0.0576595399457578 0.1827953867238 0.0138546861400624 0.0057895334881982 +Inner mitochondrial membrane organization 9 22 2.19448605139817 0.0282004856376005 9.985436893203884 20.800970873786408 1.138268089020681 0.2873707765098114 4.6289277788641146 2.4012939531921327 1.609232985153232 0.3229583948801056 0.075203654489855 0.1635258499471353 0.048990890514732 0.2269450626655096 5.28545782152457e-05 +Calcium mediated signaling 6 23 2.190957965191348 0.0284548344421899 4.538834951456311 18.50242718446602 0.6092287356409146 0.5038251477928647 2.523856388514679 2.605538151751357 0.8029171469877773 0.3120022623859673 0.2707406645426786 0.3306605597140526 0.1897338295109766 0.0513905127941343 0.1093886888682562 +Inorganic anion transport 12 27 2.187416252259194 0.028712150801841 9.900485436893204 25.351941747572816 1.3590123122148194 0.2025490755989976 4.608697956226863 4.352203003870329 1.5972877171217004 0.2769639658120273 0.0525515518253844 0.2835996474450377 0.1421535555390922 0.0260351232348132 0.0060441570275233 +Ph reduction 3 12 2.176052793291285 0.0295513131969131 4.422330097087379 12.509708737864075 1.1966830084586066 0.1930048880851129 1.91475781321527 1.7851607614701208 1.4167744165903868 0.2497649393583847 0.0047113831635554 0.1263420182810564 0.0023694947377154 0.0044180066438726 0.0451666412494461 +Cellular response to increased oxygen levels 1 6 2.175988365770801 0.0295561305120402 1.6504854368932038 6.385922330097087 1.138869139630967 0.2726341581961526 1.2184562719610088 0.8029653015671253 0.9206381175249092 0.2739573544488438 0.0090809806489247 1.0 0.0056684159955205 0.0331187861076589 0.113339965404402 +Glial cell proliferation 2 8 2.1754419218222014 0.029597015879629 1.6262135922330097 5.412621359223301 1.1035845317400614 0.2421873681292294 1.0594430818589295 1.1842969002295405 1.0977939547178823 0.257309212646388 0.0318919308376235 0.1049896535105009 0.0202898922491691 0.0175758241055335 0.09905667817091 +Proteoglycan metabolic process 4 8 2.167940415129809 0.0301632203493011 3.0558252427184467 7.347087378640777 0.90943742591388 0.2775323863615319 1.813993622553226 2.3052106999156825 1.19959130355936 0.2714444012698452 0.0973150184386021 1.0 0.3404254693467198 0.0862589503665335 0.0566259049269907 +Negative regulation of secretion 4 18 2.1613271118545434 0.0306700800525281 4.148058252427185 18.021844660194176 0.8973427539161298 0.3984823243406039 2.1406652437798495 2.8560969523306214 0.8942114095598058 0.3123655158346225 0.0453608167005379 0.2695684389372801 0.0244837275894334 0.2100263434971256 0.2095200016460435 +Metal ion homeostasis 25 81 2.146366064502305 0.0318437845728316 22.37864077669903 79.5 0.7762327689006491 0.4501210966631583 8.485414676383348 8.298876985671072 1.3957415688189287 0.3857448193070677 0.1042259386344333 0.3617750709606537 0.0408976472683376 0.0564867987008294 0.0178612960826133 +Cytochrome complex assembly 8 14 2.1409524067952037 0.0322778762818811 5.339805825242719 11.616504854368932 1.5489281771301031 0.1834582376033618 2.45860248431673 2.439266047793512 1.3189185418401956 0.2620853228235733 0.0648502590755818 0.151306852499084 0.2802926639431586 0.0489147892655661 0.0816645346360282 +Regulation of secretion 30 102 2.1360544001294404 0.0326749799654395 19.521844660194176 89.43203883495146 0.3107106293169513 0.7189453252223079 6.646190857017904 10.524485676543694 0.6342572440447461 0.3131519415494544 0.4587986598707227 0.7490691544617561 0.2891134304910702 0.1523528364995074 0.0205555470470893 +Response to oxygen levels 11 66 2.128619975187347 0.0332857144987974 12.5 62.737864077669904 0.8042614609462893 0.4659445696529398 5.042296826006319 7.106965221607376 0.959407798819026 0.3671515409983293 0.0025404140788064 0.065266478136096 0.0025308725508348 0.0026494760063627 0.1484080532371725 +Regulation of release of cytochrome c from mitochondria 6 14 2.1274441029314333 0.0333832010242183 3.6310679611650487 10.805825242718448 0.7924389389582319 0.4006886058463786 1.815469081442188 1.3603843861930187 0.9712392086725492 0.3199873643457663 1.0 1.0 1.0 0.0064140084647031 0.0005931675183369 +Schwann cell differentiation 3 11 2.126484029708001 0.0334629776274555 2.728155339805826 8.487864077669903 0.0772419244875512 0.5793500773339586 1.8138848228668836 2.129849874141248 0.8733832080799478 0.3006049084677616 0.0458040367234424 0.1263420182810564 0.2372212797486779 0.029757296929711 0.0451666412494461 +Phosphatidic acid metabolic process 1 5 2.1177305256086703 0.0341978960850331 2.2233009708737863 6.235436893203883 0.8816881639607732 0.2856229767394486 1.614148841412113 1.5439850574626743 1.1927985254107716 0.2824496640110863 0.0400077618678618 1.0 0.0255840399150975 0.1309570889500886 0.3640245481081547 +Inorganic ion transmembrane transport 32 120 2.1134704269321225 0.0345605236046102 32.300970873786405 111.99514563106796 0.9881513097876132 0.4268253140664947 13.185263141323642 11.586314982845243 1.7161030277526947 0.4113555760685328 0.05902917956735 0.0235119566106377 0.0462706575593131 0.0093674170776264 0.0091232786394846 +Mitochondrial fusion 6 14 2.111060401504208 0.0347671204882389 5.730582524271845 14.140776699029129 0.9082040747396848 0.3521825448687026 2.97444400458197 2.016819417247653 1.0465735301082626 0.3054031781597867 1.0 1.0 1.0 1.0 0.0003831746340893 +Negative regulation of cation channel activity 3 8 2.10908959718796 0.0349368486273704 2.133495145631068 6.012135922330097 0.3843341472061108 0.4773896383730598 1.4478455428656238 1.1179681209181225 0.991066221927023 0.3079680390661607 0.1992649039447594 0.083126337411673 0.1596960736798767 0.0088528623379573 0.0098879726868235 +Golgi to plasma membrane protein transport 9 20 2.106179768624558 0.0351887398476946 4.45873786407767 16.08495145631068 0.1288238576094092 0.70739074460277 2.7511244584085417 1.950869048959258 0.602797628875931 0.2627156665210308 1.0 1.0 1.0 0.0563589352178582 0.0002718910108126 +Cellular response to oxygen levels 8 39 2.1021593121005195 0.0355393226667453 8.393203883495145 36.271844660194176 0.9126927578207408 0.4163034805851183 3.607671495386698 4.048118764224637 0.9088125816374436 0.3418533733797396 0.010441112025746 0.4072806445693771 0.0201115001422002 0.0012412227882216 0.0804561618017468 +Protein localization to microtubule organizing center 7 14 2.101916521815516 0.035560588995231 3.655339805825242 10.949029126213592 -0.0810316112102637 0.620107147835328 2.1116058470898498 2.551379605694838 0.7621589677381015 0.281806770500618 1.0 1.0 1.0 0.0525727870350727 0.0888289826938022 +Synaptonemal complex organization 1 7 2.0939039250844425 0.0362685395594306 1.470873786407767 6.174757281553398 0.723394588880887 0.4361908449153728 1.1810092004903878 0.7330900746788283 0.8281604841906476 0.2971095774097388 0.0062915800142223 0.0470522829573702 0.0921025797166938 0.0233125205204954 0.0823369674942117 +Negative regulation of gliogenesis 2 6 2.090711508741695 0.036553932701006 1.3470873786407769 5.104368932038835 0.7908721225635217 0.3008340423028514 0.9967988871839628 1.1559387979758486 1.13650278668033 0.2567959459302846 0.0023364039281307 0.1006582454154426 0.018640880521655 0.0155574138143109 0.0892170338783466 +Cation transport 47 165 2.0895396344450585 0.0366591740312878 40.9247572815534 152.4733009708738 1.0106305648473772 0.4693050539746304 15.98502541638414 15.374508146736815 1.5607432077940149 0.4143686874753333 0.2648527613246294 0.0091015487948617 0.1048070711565826 0.0340484695772904 0.0021377280108296 +Lipoprotein metabolic process 3 18 2.0720487980356763 0.0382608906087362 5.504854368932039 19.114077669902912 1.0723975558987071 0.2794846862458811 2.648039342123219 3.7213756556771336 1.2556798055308762 0.2951644225033464 0.2798507356017818 0.0627750690965546 0.1967082241040804 0.152340992243069 0.6002808869874628 +Mammary gland development 9 24 2.071955464836479 0.038269594655907 5.216019417475728 20.41747572815534 0.5512318000747981 0.5167791069166561 2.3942560065426757 2.728043047822029 0.8380822573448591 0.3178008321809467 0.2798507356017818 0.0627750690965546 0.1967082241040804 0.152340992243069 0.1200224502842224 +Regulation of hormone metabolic process 3 5 2.070058949826692 0.0384468244193692 1.9199029126213591 5.327669902912621 0.9387613573830266 0.3058102715557096 1.1578738425382251 0.5676654694542113 0.9983912186719198 0.2773016546183636 1.0 1.0 1.0 0.0840389641709933 0.0708751155690715 +Vacuolar acidification 2 8 2.0635215049707725 0.039063106772853 3.4757281553398056 8.922330097087379 1.27407749822917 0.1611429668415415 1.4148632661931722 1.303016071016461 1.4195929612668792 0.2212670077717619 0.0012830471532705 0.083126337411673 0.0006327439593496 0.0088528623379573 0.0544656750173612 +Outer mitochondrial membrane organization 1 5 2.0630162540723145 0.0391110839097086 1.4296116504854368 4.956310679611651 1.1531610290328034 0.2630141305877053 0.9963023114429655 0.2044029443827893 0.89744850896642 0.2676384061848394 0.0598253058286238 0.0238038053541035 0.0471521402185075 0.0056136137273067 0.0214944247869924 +Positive regulation of membrane potential 2 6 2.0587341905566388 0.0395197090014149 1.6820388349514563 5.269417475728155 0.2153741453957751 0.6053146084020592 1.1335003430162955 0.9045390664871223 0.7631279859079874 0.2889540254998121 0.1269454833803885 0.0516364610584135 0.1008375048293403 0.0280420066437826 0.0141665154869097 +Neuron projection regeneration 5 11 2.0576011741636706 0.0396284338586776 2.3058252427184467 9.79611650485437 0.887202443720293 0.3987106095324453 1.3505356896696743 1.5461145996848544 0.8042022398095918 0.2932545495700766 0.0088454804144021 0.1553991536419083 0.0443091130960601 0.0525727870350727 0.0261400621732643 +Mitochondrial calcium ion transmembrane transport 4 9 2.057546455374103 0.0396336911229899 3.4684466019417477 9.04126213592233 0.7792467211325117 0.2463779000555085 2.196969341156949 1.2010296388602075 1.3738174116662032 0.263849842646199 1.0 1.0 1.0 0.0062969264366488 0.0007525839576665 +Negative regulation of neuron projection development 5 21 2.051081469296026 0.0402590135908029 4.944174757281553 19.932038834951456 0.8070712719008988 0.4165241941447024 2.3357271686464363 2.7475042016888107 0.8484003015222881 0.3001902418041021 0.0771449781692383 0.3241278561278478 0.0428883183388871 0.0471193490858285 0.2020238689192633 +Positive regulation of sequestering of calcium ion 2 5 2.047270134451282 0.040631568565451 1.444174757281553 4.065533980582524 0.3321131309656542 0.4579950429194244 1.118810936310271 0.8232521681359034 1.085014771474357 0.320683899890456 0.0940017828732331 0.0378187125466048 0.0743799864466655 0.014977467250991 0.0053637976870067 +Negative regulation of ryanodine sensitive calcium release channel activity 2 5 2.047270134451282 0.040631568565451 1.444174757281553 4.065533980582524 0.3321131309656542 0.4579950429194244 1.118810936310271 0.8232521681359034 1.085014771474357 0.320683899890456 0.0940017828732331 0.0378187125466048 0.0743799864466655 0.014977467250991 0.0053637976870067 +Negative regulation of calcium ion transport into cytosol 2 5 2.047270134451282 0.040631568565451 1.483009708737864 4.230582524271845 0.3306337803947523 0.4637675394464941 1.1222388639977254 0.9361855318182722 1.0781916094045627 0.3229994495869239 0.1269454833803885 0.0516364610584135 0.1008375048293403 0.0280420066437826 0.0141665154869097 +Cellular monovalent inorganic cation homeostasis 16 27 2.046868327617513 0.0406710146152569 8.191747572815533 25.12378640776699 1.1978511848260835 0.2636491484517694 3.558748260132903 2.9783551257949803 1.4212259473978417 0.3021468238591936 0.0387001795193389 0.2552681350600493 0.0207328276809773 0.0035372417514602 0.0281223334511535 +Purine nucleoside biosynthetic process 1 6 2.034918452804274 0.0418590789432493 1.4611650485436891 5.742718446601942 0.8935109670252933 0.3592786141720023 1.2698698816998135 0.508968486969168 1.0201063575252725 0.3098922359465458 0.0062915800142223 1.0 0.0039135152062846 0.0233125205204954 0.0823369674942117 +Organic cation transport 3 5 2.0236562082176355 0.0430055373396638 2.191747572815534 5.524271844660194 1.626219676916526 0.1372808582950073 1.481153399412497 1.209546654977186 0.871004228766265 0.1892257790071234 0.2284093077750681 0.0963063052639835 0.1837383274168749 0.4040612158985918 0.0798154053066686 +Homologous chromosome segregation 2 11 2.0227384544635405 0.0431001199984242 2.9441747572815533 9.983009708737864 0.8658101820521615 0.3886675393312038 1.6544409340956687 1.448870557748215 0.8756753907408087 0.3062582021532934 0.0488111156132814 0.1305522111527444 0.2445730022705269 0.0326106125072858 0.1659016353191164 +Negative regulation of nervous system development 5 20 2.021214884231222 0.0432575255832441 4.225728155339806 17.99514563106796 0.4680685636974716 0.419713233745777 2.1977522064718618 2.960086545598349 1.0442754970945465 0.2873726818408866 0.070588315436563 0.314211533829163 0.1724639155075248 0.1217442040930612 0.1795318198605321 +Trophectodermal cell differentiation 2 6 2.019267750555616 0.0434593978801827 1.8786407766990292 5.771844660194175 0.2193516802673712 0.5360986134379336 1.710853445428719 0.9982428713687248 0.924068455384751 0.3106656708797944 0.1893094745604938 1.0 0.1515272625734178 0.3422564852890665 0.1998160014011807 +Regulation of blood pressure 4 18 2.017504470757503 0.043642894945622 5.762135922330097 17.737864077669904 1.3077123393993415 0.1882731913471478 2.2751770017499977 2.3871059987956724 1.372929386780725 0.2480453688154592 0.0054823934352529 0.2443632781182481 0.0181443698350236 0.0131393408571549 0.1513315101249232 +Peptidyl arginine n methylation 3 6 2.010809608386897 0.0443455708495785 2.1092233009708736 5.269417475728155 0.4578179390299605 0.5114911620550099 1.4465265993281495 0.7225471735098173 0.9037274161000616 0.3204634427070337 1.0 1.0 1.0 0.0233125205204954 0.010684483318579 +Peptidyl arginine methylation 3 6 2.010809608386897 0.0443455708495785 2.1092233009708736 5.269417475728155 0.4578179390299605 0.5114911620550099 1.4465265993281495 0.7225471735098173 0.9037274161000616 0.3204634427070337 1.0 1.0 1.0 0.0385233102424958 0.0228394808772788 +Bergmann glial cell differentiation 1 6 2.007075612458155 0.0447416125218853 1.4635922330097086 4.883495145631068 0.2432230701216105 0.5985855589785339 1.362156595626081 0.8623851647068913 0.8032194403691936 0.2972106684584192 0.0030076637467772 1.0 0.0018609890552042 0.011414919510753 0.0423042030727838 +Protein insertion into membrane 13 31 2.004138451921947 0.0450552314172192 9.861650485436892 27.67718446601942 1.4180388387951812 0.2751856944202687 4.426616888970974 3.3195747527036987 1.508549988584809 0.3318307488597651 0.024440781095221 0.0248381956323572 0.0128487417044244 0.034999603504981 0.0030132274761459 +T cell apoptotic process 3 13 2.003959457636485 0.04507440352351 2.145631067961165 10.701456310679612 0.7461760702030203 0.3927793123326719 1.654107960636956 1.7995948345334825 0.9259723405034824 0.2877845742037807 0.0042441954196643 0.1221118561195742 0.0021303683071518 0.0038594647505617 0.0402069493791732 +Regulation of protein folding 2 5 2.003883383007404 0.045082553971866 1.4684466019417477 3.9902912621359223 0.8007742626376635 0.414912404617451 0.9636472557717446 0.4350012974217447 0.8403398140210957 0.3064934164835685 1.0 1.0 1.0 0.1583736196074974 0.0423042030727838 +Positive regulation of mitochondrial membrane potential 2 5 1.996606596356243 0.0458679357245657 1.364077669902913 3.8592233009708736 0.466365083303736 0.5595064518974401 0.9621329832525916 0.6999218948386602 0.7924469360841313 0.3081726674594855 0.0940017828732331 0.0378187125466048 0.0743799864466655 0.014977467250991 0.0053637976870067 +Regulation of golgi organization 4 8 1.9927109438011703 0.0462931083258824 1.944174757281553 7.259708737864078 0.4938360404065116 0.4881247097287292 1.6646787638867808 1.6274430217223506 0.8799056721214452 0.3073140855538377 0.1992649039447594 1.0 0.1596960736798767 0.3582816735878424 0.0544656750173612 +Bone morphogenesis 3 8 1.9926721039502824 0.0462973639681598 2.3737864077669903 7.519417475728155 0.7918915806069479 0.3290665752918499 1.3241931901591228 1.4011478132752644 1.0549507058478411 0.2731796281548322 1.0 1.0 1.0 0.2994428025832826 0.174947649934789 +Intermediate filament organization 2 8 1.9915631591133367 0.0464190089375691 2.2233009708737863 6.087378640776699 0.2623037643723794 0.4180828699239641 1.2535931954616677 0.8315011120555454 1.1682966764755611 0.3104064442188157 0.0106465592757744 1.0 0.1180585699575878 0.0033939033653995 0.0228394808772788 +Homologous chromosome pairing at meiosis 2 9 1.9879807418764524 0.0468138199021379 2.4975728155339807 8.245145631067961 0.965829654578573 0.3348869860078453 1.4047402178514554 0.97323438747629 0.9242483632276672 0.2995534430572119 0.0245269934238486 0.0919337377678228 0.1758008751515455 0.0119341177484456 0.0708751155690715 +Sphingolipid biosynthetic process 3 19 1.9834006506051371 0.0473226945191631 6.543689320388349 16.33252427184466 1.3108583596388097 0.2293036031089034 3.2058099533310203 2.4273143169149307 1.5209865792019848 0.2861850290041513 0.0355725969687039 0.2480154974279715 0.1100932826860655 0.0549638769430376 0.1591907444431843 +Amyloid precursor protein catabolic process 8 19 1.978908691810369 0.0478262874846664 4.62621359223301 16.47087378640777 1.203006467000838 0.2754962460876 2.1329801006381106 2.1803683249886516 0.947433834000198 0.2709877848980267 0.4195293342885178 1.0 0.3467918934582977 0.0909853548684221 0.0050026695308212 +Regulation of glial cell proliferation 1 5 1.975181184191569 0.0482475903956269 0.9563106796116504 4.089805825242719 0.9341050469143442 0.3274204875894432 0.8829748814899869 0.9675276073756384 1.0425311720733597 0.2839327622585455 0.0179800497482818 0.0786913117950012 0.0113213926532688 0.0630532374058985 0.1998160014011807 +Monovalent inorganic cation homeostasis 11 29 1.9726304299978297 0.0485376834421416 9.014563106796116 27.87378640776699 1.1567920478867002 0.2845186374336156 4.051822262152646 3.607380814764068 1.4117439861533438 0.3149022278800241 0.0602575146581244 0.297366720714231 0.033011066423499 0.0085250028508827 0.0642903416117007 +Toxin transport 4 13 1.971711832019784 0.0486425121678624 3.5606796116504853 12.470873786407768 0.1674377829201756 0.6471359079576875 3.491836182651976 1.1133027107744335 0.7001486990935661 0.2811671395670961 0.0428688471843709 0.1221118561195742 0.2297987482657219 0.1392702662277763 0.1423023069394473 +Transmembrane transport 64 232 1.970586694238568 0.0487711698010722 67.45631067961165 211.1359223300971 1.8122664376950308 0.3598356673827246 27.267027885156203 22.354947126810902 2.251277763144546 0.4188333713481413 0.005524043464458 0.0008488822631774 0.0034128829994973 9.410049050535744e-05 6.329565364384183e-05 diff --git a/msigdb_gobp/metrics.json b/msigdb_gobp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..1858629868e112180b7caa2335369b6e25c5cc17 --- /dev/null +++ b/msigdb_gobp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3381, + "annotations_size": 6609, + "title": "Average number of proteins per term", + "value": 20.393402935391133 +} \ No newline at end of file diff --git a/msigdb_gobp/paths.json b/msigdb_gobp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..b16ac7778f687e61df96514feb7c359896e1233b --- /dev/null +++ b/msigdb_gobp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gobp/fragment/C317/C317_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gobp/result.tsv b/msigdb_gobp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..fd04b7ff18d602962c43fc13c57596d552fbabe0 --- /dev/null +++ b/msigdb_gobp/result.tsv @@ -0,0 +1,2047 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mitochondrial transport 0.5424505702730019 3.695114324979344 0.0002197878699008 0.7660710132439896 0.7069019432353718 84 O60830,O60220,Q9Y5J7,Q9Y5J9,Q8N8Q8,Q15388,Q9NS69,Q99595,P49257,O14737,O00170,Q10713,Q96EK5,P00846,O43772,O14925,P52789,Q8N4H5,P30536,O75964,P55786,Q8TB36,Q53H12,P06576,O95429,O43464,P24539,O95831,P45880,Q14849,Q9GZY8,Q5JRX3,Q9UBX3,Q96QK1 34 +Protein targeting 0.5110090864122062 3.490130592154946 0.0004827845628552 0.958889579104348 0.7069019432353718 120 P40855,O60830,P57105,O60220,P31751,Q9Y5J7,Q9Y2T2,P46379,Q7L5D6,Q15388,Q9Y5J9,Q9NS69,O43681,Q99595,O60725,P49257,P50542,O00170,Q10713,O14737,P43307,Q9H9H4,O75381,O14925,Q8N4H5,P10909,P30536,Q13438,Q6ZWJ1,Q9UHB9,P55786,Q8TB36,Q53H12,Q15005,P33908,O95429,Q9Y5Y5,O43464,Q9Y5M8,O00159,Q15629,O95831,Q96RT1,O14964,Q9GZY8,Q5JRX3 46 +Establishment of protein localization to membrane 0.4679608982994129 3.105489272747638 0.0018996451111958 0.9999965137867952 0.9086240350367574 102 P40855,Q9H4A5,O60220,P31751,Q9Y5J7,P46379,Q7L5D6,Q8N8Q8,Q9Y5J9,Q9NPA0,Q9NS69,O43681,Q9BZG1,O60725,Q96A33,Q13439,P50542,O14737,Q9HD26,P43307,Q9H9H4,Q9UHB9,Q13277,Q9H4A6,Q53H12,P98194,Q9Y5Y5,Q01082,Q9UJY4,Q15629,Q9HD20,Q4J6C6,Q4V328,Q9GZY8,P0DP25,P49069,O15027,Q96QK1 38 +Protein localization to mitochondrion 0.582886111105696 2.883229730865957 0.0039362026012956 0.9999999999952158 0.9086240350367574 61 O60220,O60830,Q9Y5J7,Q9Y5J9,Q8N8Q8,Q15388,Q9NS69,Q99595,P49257,O14737,O00170,Q10713,O14925,P52789,Q8N4H5,P31749,O00429,P30536,P55786,Q8TB36,Q53H12,Q9Y6C9,O43464,O95831,Q9GZY8,P0DP25,Q5JRX3 27 +Golgi organization 0.5840992483516114 2.8277783522229285 0.0046872246940699 0.9999999999999672 0.9086240350367574 59 Q7RTS9,Q9H4A5,Q9BVK6,Q8TBA6,Q13190,P49257,P50570,P42858,Q5VU43,Q8NHH9,O43752,Q08379,Q9H4A6,Q15363,Q9H6U6,Q99996,Q8NCM8,Q9P2W9,P49755,Q9UID3,O60763,P06493,O15027,O15260 24 +Cellular ion homeostasis 0.4335933814986821 2.7714218506391037 0.0055812067795864 1.0 0.9086240350367574 90 P55011,P62942,Q9Y4W6,Q96A33,P42858,Q8NEW0,Q9BPX6,Q96TC7,P0CG08,P05023,Q9HC07,P78417,Q9Y6M7,Q93050,Q8IYU8,P06576,P98194,P09601,Q9Y487,Q05086,Q8N511,Q9HD20,O75880,P0DP25,P16615,P09429,Q9NWR8 27 +Protein targeting to mitochondrion 0.6074947474316503 2.700593032016424 0.0069215976008025 1.0 0.9086240350367574 46 O60220,O60830,Q9Y5J7,Q9Y5J9,Q15388,Q9NS69,Q99595,P49257,O14737,O00170,Q10713,O14925,Q8N4H5,P30536,P55786,Q8TB36,Q53H12,O43464,O95831,Q9GZY8,Q5JRX3 21 +Endomembrane system organization 0.4743571368711228 2.5718149708520555 0.0101166944099413 1.0 0.9086240350367574 182 O43633,Q7RTS9,Q9H4A5,P31751,Q9BVK6,P46379,Q7L5D6,Q9NQC3,O95197,Q9NPA0,Q96A33,O43681,Q96ED9,Q8TBA6,Q13190,P49257,Q12981,P50542,P50570,Q16739,P42858,Q5VU43,Q9H9H4,Q5JRA6,Q8NHH9,P10909,P31749,O94901,O43752,O00429,O95721,Q08379,Q13277,Q9H4A6,Q15363,Q8N1F7,Q9H6U6,Q01082,Q13501,Q86XL3,Q9UQB8,Q15075,Q4KMQ2,Q99996,Q8NCM8,P16220,Q15629,Q9P2W9,P49755,Q8IXJ6,Q9UID3,O43760,O14964,O60763,P06493,P16615,Q8WUX9,O75844,P35579,P50402,Q9BRG1,P49069,O15027,Q8N3R9,O15260 65 +Calcium ion import 0.7315706395180432 2.5476879518261812 0.0108439421214054 1.0 0.9086240350367574 13 Q8IYU8,P16615,O75844,Q9NWR8,P21796,Q9BPX6 6 +Metal ion transport 0.4290851918040793 2.540997436532681 0.0110536729957919 1.0 0.9086240350367574 109 P55011,P62942,Q08209,Q9Y4W6,Q96QD8,P42858,Q8NEW0,Q9BPX6,P05023,P30536,P31749,O15173,O00429,Q9HC07,P78417,Q9Y6M7,P33176,Q8IYU8,O43707,Q14BN4,P21796,P98194,O43865,Q13555,P61201,Q99996,Q9UMX0,Q9HD20,P35609,Q6P4Q7,P0DP25,P16615,O75844,Q9NWR8 34 +Protein transmembrane transport 0.6040305961760276 2.4781039948938735 0.0132082641162898 1.0 0.9086240350367574 28 O75381,O14925,O60830,P31751,Q9NS69,Q99595,Q15629,O95831 8 +Intracellular protein transmembrane transport 0.6052364819159579 2.4763650727929396 0.0132727782640418 1.0 0.9086240350367574 24 O75381,O14925,O60830,P31751,Q99595,Q15629,O95831 7 +Chloride transport 0.727494792207322 2.461850333864286 0.0138222332483575 1.0 0.9086240350367574 12 P55011,Q96S66,P30536,P54105,Q9C0H2,Q9UHG3 6 +Negative regulation of calcium ion transmembrane transport 0.7781372033042145 2.4531775150277277 0.0141600441373388 1.0 0.9086240350367574 10 Q9UMX0,P21796,P78417,P0DP25 4 +Negative regulation of calcium ion transport 0.7781372033042145 2.4531775150277277 0.0141600441373388 1.0 0.9086240350367574 10 Q9UMX0,P21796,P78417,P0DP25 4 +Purine ribonucleoside metabolic process 0.8240834790592694 2.44019115899993 0.0146794918266708 1.0 0.9086240350367574 8 O60725,P00813 2 +Positive regulation of establishment of protein localization 0.4149731302078651 2.433095095007028 0.0149703685900637 1.0 0.9086240350367574 100 O95563,Q9H4A5,P31751,Q9Y282,O14737,Q9H3S7,Q9NR31,O75312,O00410,O00429,P55786,Q9H4A6,Q9C0E2,P15311,Q9H6U6,P98194,O43464,P12270,Q66GS9,P78371,P49755,Q5T9L3,P35580,Q9GZY8,P06493,P50402,Q92544,P49368,Q96QK1 29 +Ion homeostasis 0.4193048497537541 2.419265883803624 0.0155518680762896 1.0 0.9086240350367574 108 P55011,P62942,Q9Y4W6,P30519,Q96A33,P42858,Q8NEW0,Q9BPX6,Q9Y5X3,Q96TC7,P0CG08,P05023,P30536,Q9HC07,P78417,Q9Y6M7,Q93050,Q8IYU8,P06576,Q14BN4,P09601,Q9Y487,Q05086,Q8N511,Q9HD20,O75880,Q6P4Q7,P0DP25,P16615,P09429,Q9NWR8 31 +Calcium import into the mitochondrion 0.8640863300427397 2.418539076563423 0.0155829717347619 1.0 0.9086240350367574 6 Q8IYU8,Q9NWR8,P21796,Q9BPX6 4 +Myelin maintenance 0.8615283560283984 2.407705539561252 0.0160531229964424 1.0 0.9086240350367574 6 P31751,P10909,P31749 3 +Antigen processing and presentation of endogenous antigen 0.8160638838653591 2.4037886898100225 0.0162261495536655 1.0 0.9086240350367574 8 Q9NZ08,Q6P179 2 +Antigen processing and presentation of endogenous peptide antigen 0.8160638838653591 2.4037886898100225 0.0162261495536655 1.0 0.9086240350367574 8 Q9NZ08,Q6P179 2 +Mitochondrial transmembrane transport 0.5532150583872628 2.39230992935698 0.0167426975303988 1.0 0.9086240350367574 53 O60830,O95563,Q9Y4W6,Q15388,Q99595,Q9BPX6,P00846,O43772,O14925,O95202,O75964,Q8IYU8,P06576,P21796,Q9H2D1,P24539,O95831,Q9NWR8,Q9BSK2,Q6P4A7 20 +Retrograde vesicle mediated transport golgi to endoplasmic reticulum 0.5896563168146426 2.3811204766382508 0.0172600659904507 1.0 0.9086240350367574 30 Q9H4A5,O43731,Q9Y282,Q8TD16,P42858,Q9P2W9,P24390 7 +Glial cell development 0.5905188233086168 2.3737663646357685 0.0176076878969801 1.0 0.9086240350367574 26 Q96P11,P10909,P31751,Q8IXJ6,P08670 5 +Glycoprotein catabolic process 0.9629090900338252 2.362388073662975 0.0181576234877258 1.0 0.9086240350367574 4 O60502 1 +Protein transmembrane import into intracellular organelle 0.6719976503855277 2.3620824783734875 0.0181725986436873 1.0 0.9086240350367574 15 O75381,Q99595,O95831,O60830 4 +Peripheral nervous system development 0.6711981604113652 2.357382698930341 0.0184042688339065 1.0 0.9086240350367574 15 Q8IXJ6,P51648,Q9NR77,P31751 4 +Regulation of ph 0.5846485815143143 2.328682215991124 0.0198759069337599 1.0 0.9086240350367574 22 Q9Y487,Q9HC07,Q9Y6M7,Q93050,Q8N511 5 +Regulation of cellular ph 0.5846485815143143 2.328682215991124 0.0198759069337599 1.0 0.9086240350367574 22 Q9Y487,Q9HC07,Q9Y6M7,Q93050,Q8N511 5 +Ensheathment of neurons 0.5811029250157933 2.3173312188408475 0.0204856959475245 1.0 0.9086240350367574 30 Q96P11,P10909,P31749,Q9Y4W6,P31751,O75312,Q9NR77,Q8IXJ6,Q15058,Q96PU8,Q7L576,Q8N3R9 12 +Ion transmembrane transport 0.446125342792397 2.3167626294480637 0.0205166657936644 1.0 0.9086240350367574 165 P55011,Q70HW3,O95563,P62942,Q9Y4W6,Q13423,O43808,P30825,P42858,Q8NEW0,Q9HD26,Q9BPX6,P00846,O43772,P0CG08,P05023,O75964,Q9UDW1,Q9HC07,P78417,Q9Y6M7,Q8IYU8,P06576,O43707,Q14BN4,P98194,P21796,Q9UHG3,Q9H2D1,Q8TB61,O43865,P00403,Q4KMQ2,Q99996,P13073,Q9HD20,Q9UMX0,P45880,P35609,Q9NWR8,Q6P4Q7,P0DP25,P16615,O75844,Q9UBX3,Q9C0H2,Q6P4A7 47 +Response to food 0.8377264485934309 2.306231443044124 0.0210977035326778 1.0 0.9086240350367574 6 P80303,P31749 2 +Cation transmembrane transport 0.4220349708152419 2.3001890887089447 0.0214375097265746 1.0 0.9086240350367574 126 P55011,Q70HW3,P62942,Q9Y4W6,Q13423,P30825,P42858,Q8NEW0,Q9BPX6,P00846,O43772,P05023,O75964,Q9UDW1,Q9HC07,P78417,Q9Y6M7,Q8IYU8,P06576,O43707,Q14BN4,P21796,P98194,P00403,Q4KMQ2,Q99996,P13073,Q9UMX0,Q9HD20,P35609,Q6P4Q7,P0DP25,P16615,Q9NWR8 34 +Protein import into mitochondrial matrix 0.7686113974586529 2.2902237715793277 0.0220083480854353 1.0 0.9086240350367574 9 Q99595,O60830 2 +Negative regulation of ion transmembrane transporter activity 0.6434302859297945 2.2759639791667605 0.0228481656239605 1.0 0.9086240350367574 16 P35609,P62942,P78417,P0DP25,Q9UMX0 5 +Peripheral nervous system axon regeneration 0.9396058891040971 2.2721941765104843 0.0230747848576706 1.0 0.9086240350367574 4 Q96G23,P30536 2 +Cytosolic calcium ion transport 0.5759683978956446 2.2660650724958056 0.0234473993562442 1.0 0.9086240350367574 25 P62942,P78417,P0DP25,Q8IYU8,P16615,P42858,Q9NWR8,P21796,Q9BPX6 9 +Mitochondrion organization 0.461162039606467 2.263548957458182 0.0236018702468505 1.0 0.9086240350367574 202 O60830,O75153,Q13505,Q8N8Q8,P03886,Q9NS69,Q99595,O00170,Q10713,Q69YU5,P52789,Q9NUQ9,Q8N4H5,P30536,P55786,Q53H12,O43676,P14406,Q9Y4P1,Q9NVT9,Q5HYI7,Q5T9A4,Q9BRT2,Q9Y2R0,O43674,Q9BSK2,Q96QK1,Q7L592,Q5MNZ6,Q9NVI7,Q15388,P49257,P50542,O14737,O95202,P31749,P10909,Q96A26,Q8TB36,O95429,P21796,Q96CU9,Q9NVA1,Q8N163,P49841,Q16543,O95831,Q6DKK2,Q9BSH4,Q9Y5L4,P0DP25,Q8N2A8,Q9Y5J7,Q9Y5J9,O60313,P42858,Q86Y39,O14925,O00429,Q9H4A6,Q9Y6C9,O43464,Q9UDX5,Q9NX63,O96000,P49815,P45880,Q9GZY8,Q5JRX3,Q8IWA4,O60220,Q9Y4W6,P56556,P53365,Q13501,O75880,Q7Z406,P17152,Q9UG56 79 +Schwann cell development 0.7378723661785548 2.2541308965352123 0.0241879344823765 1.0 0.9086240350367574 10 Q8IXJ6,P31749,P31751 3 +Ribonucleoside metabolic process 0.7576851222651403 2.237763288082196 0.0252364956490755 1.0 0.9086240350367574 9 O60725,P00813 2 +Plasma membrane organization 0.5679664124166044 2.2278299904534484 0.025891854143347 1.0 0.9086240350367574 32 O43633,P10909,P31749,P31751,Q9UQB8,P16615,P35579,Q16739,Q8N3R9,Q01082 10 +Intermediate filament bundle assembly 0.9257679313347218 2.2182195573491392 0.0265398658831426 1.0 0.9086240350367574 4 P07196 1 +Inner mitochondrial membrane organization 0.566053819852824 2.19448605139817 0.0282004856376005 1.0 0.9086240350367574 22 O60220,Q9Y4W6,Q13505,Q9Y5J7,Q9Y5J9,P17152,O60313,Q5HYI7,Q9NX63 9 +Calcium mediated signaling 0.5657157514180523 2.190957965191348 0.0284548344421899 1.0 0.9086240350367574 23 P78417,P0DP25,P16615,O75844,P42858,P00813 6 +Inorganic anion transport 0.5649618101332865 2.187416252259194 0.028712150801841 1.0 0.9086240350367574 27 P55011,Q96S66,P0CG08,P30536,Q9Y6M7,O43681,P54105,Q9UBX3,Q9C0H2,P21796,Q9UHG3,P45880 12 +Ph reduction 0.674631693880379 2.176052793291285 0.0295513131969131 1.0 0.9086240350367574 12 Q9Y487,Q8N511,Q93050 3 +Cellular response to increased oxygen levels 0.8075829340038979 2.175988365770801 0.0295561305120402 1.0 0.9086240350367574 6 Q9Y487 1 +Glial cell proliferation 0.7665269754661488 2.1754419218222014 0.029597015879629 1.0 0.9086240350367574 8 Q96G23,P30536 2 +Proteoglycan metabolic process 0.7649214257071483 2.167940415129809 0.0301632203493011 1.0 0.9086240350367574 8 Q8NCH0,Q9NX62,Q99805,Q7LGA3 4 +Negative regulation of secretion 0.5949654971360624 2.1613271118545434 0.0306700800525281 1.0 0.9086240350367574 18 Q16836,Q16850,P00813,P09601 4 +Metal ion homeostasis 0.426308575380167 2.146366064502305 0.0318437845728316 1.0 0.9086240350367574 81 P55011,P62942,Q9Y4W6,P30519,Q96A33,P42858,Q8NEW0,Q9BPX6,Q9Y5X3,Q96TC7,P05023,Q9HC07,P78417,Q8IYU8,P98194,P09601,Q9Y487,Q8N511,Q9HD20,O75880,Q6P4Q7,P0DP25,P16615,P09429,Q9NWR8 25 +Cytochrome complex assembly 0.6470327572610479 2.1409524067952033 0.0322778762818811 1.0 0.9086240350367574 14 O75880,Q9Y2R0,Q6DKK2,Q8N8Q8,Q9BSK2,Q69YU5,Q9NVA1,Q9BRT2 8 +Regulation of secretion 0.3944858066846414 2.1360544001294404 0.0326749799654395 1.0 0.9086240350367574 102 P55011,O43633,Q16836,O95563,Q9H4A5,Q08209,O43768,Q9Y5X3,Q16850,Q9H3S7,O00429,Q6ZWJ1,Q32P28,Q9UNH7,Q9H4A6,P15311,P00813,P09601,Q96KC8,Q9Y2G5,P16220,P49755,Q5T9L3,Q9BRT2,P14174,Q4J6C6,O14964,P35580,P0DP25,P16615 30 +Negative regulation of organic acid transport 0.9045340065918118 2.134801203079224 0.0327772519866051 1.0 0.9086240350367574 4 P31751 1 +Response to oxygen levels 0.4855670202313059 2.128619975187347 0.0332857144987974 1.0 0.9086240350367574 66 P00846,P09601,P31749,Q8IXJ6,Q9Y487,P30519,Q96A26,P55786,Q8N511,Q9UMX0,P00813 11 +Tetrapyrrole catabolic process 0.9029009355293308 2.128355999758671 0.033307578338714 1.0 0.9086240350367574 4 P30519 1 +Regulation of release of cytochrome c from mitochondria 0.6447210455256429 2.1274441029314333 0.0333832010242183 1.0 0.9086240350367574 14 P10909,P31749,O00429,Q96A26,O60313,O14737 6 +Schwann cell differentiation 0.6895019708771589 2.1264840297080014 0.0334629776274555 1.0 0.9086240350367574 11 Q8IXJ6,P31749,P31751 3 +Phosphatidic acid metabolic process 0.8441450078072831 2.1177305256086703 0.0341978960850331 1.0 0.9086240350367574 5 Q9NPH0 1 +Inorganic ion transmembrane transport 0.4045585280242351 2.1134704269321225 0.0345605236046102 1.0 0.9086240350367574 120 P55011,P62942,Q9Y4W6,Q13423,P42858,Q9BPX6,P00846,P05023,O75964,Q9UDW1,Q9HC07,P78417,Q9Y6M7,Q8IYU8,P06576,O43707,Q14BN4,P21796,P98194,Q9UHG3,P00403,Q4KMQ2,Q99996,P13073,Q9UMX0,Q9HD20,P35609,Q6P4Q7,P0DP25,P16615,Q9UBX3,Q9NWR8 32 +Mitochondrial fusion 0.6419217807525945 2.111060401504208 0.0347671204882389 1.0 0.9086240350367574 14 Q8N2A8,Q9GZY8,O60313,Q9NX63,Q8IWA4,Q9Y6C9 6 +Negative regulation of cation channel activity 0.7523718832609286 2.10908959718796 0.0349368486273704 1.0 0.9086240350367574 8 Q9UMX0,P78417,P0DP25 3 +Golgi to plasma membrane protein transport 0.553292566326343 2.106179768624558 0.0351887398476946 1.0 0.9086240350367574 20 Q9H4A5,Q4J6C6,Q13439,Q9BZG1,Q9H4A6,Q9UJY4,O15027,Q01082,Q9HD26 9 +Cellular response to oxygen levels 0.5453156315869824 2.1021593121005195 0.0355393226667453 1.0 0.9086240350367574 39 P09601,P31749,Q8IXJ6,Q9Y487,Q96A26,P55786,Q8N511,Q9UMX0 8 +Protein localization to microtubule organizing center 0.6403616312485522 2.101916521815516 0.035560588995231 1.0 0.9086240350367574 14 Q13561,P49841,Q9BV73,P25054,Q15154,Q9P2S5,Q8WXW3 7 +Synaptonemal complex organization 0.7694003849359834 2.0939039250844425 0.0362685395594306 1.0 0.9086240350367574 7 P46379 1 +Negative regulation of gliogenesis 0.7880840470380633 2.090711508741695 0.036553932701006 1.0 0.9086240350367574 6 Q96G23,P30536 2 +Cation transport 0.4293650706068724 2.0895396344450585 0.0366591740312878 1.0 0.9086240350367574 165 P55011,Q70HW3,P62942,Q08209,Q9Y4W6,Q96QD8,Q13423,O43808,P30825,P42858,Q8NEW0,Q9BPX6,P00846,O43772,P05023,P30536,O75964,Q9UDW1,P31749,Q9HC07,P78417,Q9Y6M7,O00429,O15173,Q8IYU8,Q9UNH7,P06576,O43707,Q14BN4,P98194,P21796,O43865,Q13555,P00403,P61201,P33176,Q4KMQ2,Q99996,P13073,Q9HD20,Q9UMX0,P35609,Q6P4Q7,P0DP25,P16615,O75844,Q9NWR8 47 +Lipoprotein metabolic process 0.5816359963582851 2.0720487980356763 0.0382608906087362 1.0 0.9086240350367574 18 Q16739,Q5MNZ6,Q9BQE5 3 +Mammary gland development 0.5496619952801668 2.071955464836479 0.038269594655907 1.0 0.9086240350367574 24 P52789,P31751,P31749,Q13505,P61201,P00403,Q9NQC3,P16220,Q9Y297 9 +Regulation of hormone metabolic process 0.8326935663229705 2.070058949826692 0.0384468244193692 1.0 0.9086240350367574 5 O60678,O75844,P16435 3 +Vacuolar acidification 0.7427103027437155 2.0635215049707725 0.039063106772853 1.0 0.9086240350367574 8 Q9Y487,Q93050 2 +Outer mitochondrial membrane organization 0.8310066203969184 2.0630162540723145 0.0391110839097086 1.0 0.9086240350367574 5 Q9NS69 1 +Positive regulation of membrane potential 0.780819034461628 2.0587341905566388 0.0395197090014149 1.0 0.9086240350367574 6 P31751,P31749 2 +Neuron projection regeneration 0.6765272704679142 2.0576011741636706 0.0396284338586776 1.0 0.9086240350367574 11 P07196,Q96G23,P30536,P00374,P10586 5 +Mitochondrial calcium ion transmembrane transport 0.7206378924407226 2.057546455374103 0.0396336911229899 1.0 0.9086240350367574 9 Q8IYU8,Q9NWR8,P21796,Q9BPX6 4 +Negative regulation of neuron projection development 0.5461393858721598 2.051081469296026 0.0402590135908029 1.0 0.9086240350367574 21 Q96G23,Q9NR77,Q05086,P08670,Q9NQC3 5 +Positive regulation of sequestering of calcium ion 0.8272393599143992 2.047270134451282 0.040631568565451 1.0 0.9086240350367574 5 P78417,P0DP25 2 +Negative regulation of ryanodine sensitive calcium release channel activity 0.8272393599143992 2.047270134451282 0.040631568565451 1.0 0.9086240350367574 5 P78417,P0DP25 2 +Negative regulation of calcium ion transport into cytosol 0.8272393599143989 2.047270134451282 0.040631568565451 1.0 0.9086240350367574 5 P78417,P0DP25 2 +Cellular monovalent inorganic cation homeostasis 0.5462460678414758 2.0468683276175135 0.0406710146152569 1.0 0.9086240350367574 27 P55011,Q9UI12,P0CG08,P05023,P05026,Q9Y487,Q9HC07,Q9Y6M7,Q05086,Q93050,Q96AX1,P61421,P06576,Q8N511,Q15904,Q92544 16 +Purine nucleoside biosynthetic process 0.7754244476986807 2.034918452804274 0.0418590789432493 1.0 0.9086240350367574 6 P00813 1 +Organic cation transport 0.8216010919834764 2.0236562082176355 0.0430055373396638 1.0 0.9086240350367574 5 O43772,Q96QD8,Q70HW3 3 +Homologous chromosome segregation 0.6699974128115463 2.0227384544635405 0.0431001199984242 1.0 0.9086240350367574 11 P46379,Q92791 2 +Negative regulation of nervous system development 0.5416472403817477 2.021214884231222 0.0432575255832441 1.0 0.9086240350367574 20 Q96G23,P30536,Q8IXJ6,Q9Y4G8,Q9NQC3 5 +Trophectodermal cell differentiation 0.7718867755717864 2.019267750555616 0.0434593978801827 1.0 0.9086240350367574 6 Q13895,P00813 2 +Regulation of blood pressure 0.5735518699360767 2.017504470757503 0.043642894945622 1.0 0.9086240350367574 18 Q9NZ08,P09601,P09493,Q6P179 4 +Peptidyl arginine n methylation 0.7699773330989367 2.010809608386897 0.0443455708495785 1.0 0.9086240350367574 6 O60678,Q6P2P2,Q86X55 3 +Peptidyl arginine methylation 0.7699773330989367 2.010809608386897 0.0443455708495785 1.0 0.9086240350367574 6 O60678,Q6P2P2,Q86X55 3 +Peripheral nervous system myelin maintenance 0.872924748373624 2.0093116314014585 0.0445040951480502 1.0 0.9086240350367574 4 P31749,P31751 2 +Bergmann glial cell differentiation 0.769134915539516 2.007075612458155 0.0447416125218853 1.0 0.9086240350367574 6 P08670 1 +Protein insertion into membrane 0.5394854200992371 2.004138451921947 0.0450552314172192 1.0 0.9086240350367574 31 O60220,Q9Y5J7,Q9Y5J9,P46379,Q8N8Q8,Q7L5D6,Q96A33,Q9NS69,O43681,Q53H12,P49069,O14737,Q15629 13 +T cell apoptotic process 0.6342005752099079 2.003959457636485 0.04507440352351 1.0 0.9086240350367574 13 P00813,P24390,Q9HCL2 3 +Regulation of protein folding 0.8168903265027415 2.0038833830074037 0.045082553971866 1.0 0.9086240350367574 5 O14737,Q9Y2G5 2 +Positive regulation of mitochondrial membrane potential 0.8151590265880809 1.996606596356243 0.0458679357245657 1.0 0.9086240350367574 5 P31751,P31749 2 +Positive regulation of erad pathway 0.8694819637425574 1.9955510480101728 0.0459828123952315 1.0 0.9086240350367574 4 P46379 1 +Regulation of golgi organization 0.7277901619096632 1.9927109438011703 0.0462931083258824 1.0 0.9086240350367574 8 Q99996,Q5VU43,Q9P2W9,Q13190 4 +Bone morphogenesis 0.7277820087479152 1.9926721039502824 0.0462973639681598 1.0 0.9086240350367574 8 Q9NX62,O75844,Q92896 3 +Intermediate filament organization 0.7275492358598026 1.9915631591133371 0.0464190089375691 1.0 0.9086240350367574 8 P07196,P08670 2 +Homologous chromosome pairing at meiosis 0.7065308459655151 1.9879807418764524 0.0468138199021379 1.0 0.9086240350367574 9 P46379,Q92791 2 +Sphingolipid biosynthetic process 0.5530167790362431 1.9834006506051376 0.0473226945191631 1.0 0.9086240350367574 19 Q16739,Q06136,Q96G23 3 +Amyloid precursor protein catabolic process 0.5523803635683655 1.9789086918103695 0.0478262874846664 1.0 0.9086240350367574 19 O75298,P62942,P10909,Q96P70,O95197,Q9NQC3,Q15392,P49755 8 +Regulation of glial cell proliferation 0.8100687508928428 1.975181184191569 0.0482475903956269 1.0 0.9086240350367574 5 P30536 1 +Positive regulation of nitric oxide synthase activity 0.8640805448623006 1.9739260142773956 0.0483901562618038 1.0 0.9086240350367574 4 P0DP25,Q8WTV0,P31749 3 +Monovalent inorganic cation homeostasis 0.5361137668084626 1.9726304299978297 0.0485376834421416 1.0 0.9086240350367574 29 P55011,Q9Y5X3,P0CG08,P05023,Q9Y487,Q9HC07,Q9Y6M7,Q05086,Q93050,Q8N511,P06576 11 +Toxin transport 0.6286070885593549 1.9717118320197835 0.0486425121678624 1.0 0.9086240350367574 13 P49368,P78371,P35606,Q93050 4 +Transmembrane transport 0.453262981385361 1.9705866942385677 0.0487711698010722 1.0 0.9086240350367574 232 P55011,Q70HW3,O95563,O60830,P62942,P31751,Q9Y4W6,Q96QD8,Q13423,Q9NS69,O43808,Q99595,Q8IXU6,P30825,P42858,Q8NEW0,Q9HD26,Q9BPX6,P00846,O75381,O14925,Q07820,P52789,P0CG08,P05023,P31749,O75964,Q9UDW1,O43772,Q6ZWJ1,P78417,Q9HC07,Q9Y6M7,Q8IYU8,P06576,O43707,Q14BN4,P21796,Q9UHG3,Q8WTV0,Q03518,Q9H2D1,Q8TB61,O43865,P00403,Q99996,Q15629,Q9HD20,Q9UMX0,O95831,P38435,P13073,P49755,P45880,P35609,O75298,Q9NWR8,Q6P4Q7,P0DP25,P16615,O75844,Q9UBX3,Q9C0H2,Q6P4A7 64 +Peroxisome fission 0.8621535864436516 1.966200725764032 0.0492754286845185 1.0 0.9086240350367574 4 O00429,P40855 2 +Negative regulation of transmembrane transport 0.5347005493346265 1.9589078631388503 0.0501235780117108 1.0 0.9086240350367574 26 P35609,P31749,P31751,P78417,P0DP25,Q9UMX0,P21796 7 +Regulation of myelination 0.6262320845547613 1.9579867749469528 0.0502315645512223 1.0 0.9086240350367574 13 Q96P11,Q7L576,P31749,Q8IXJ6,Q15058 5 +Negative regulation of glial cell proliferation 0.9546592173146332 1.95518104106964 0.0505617055050469 1.0 0.9086240350367574 3 P30536 1 +Positive regulation of intracellular transport 0.4350727782601509 1.9440702511805417 0.0518869800918051 1.0 0.9086240350367574 75 P31751,Q9Y282,Q15154,Q07666,O14737,Q9H3S7,Q9NR31,O75312,O00410,P55786,Q9C0E2,P15311,Q9H6U6,O43464,P49841,P12270,Q9P2W9,P35609,Q9GZY8,P06493,P50402,Q92544 22 +Proteoglycan biosynthetic process 0.7546108891499319 1.942469793508352 0.0520802532790929 1.0 0.9086240350367574 6 Q8NCH0,Q99805,Q7LGA3 3 +Regulation of mitochondrion organization 0.5128027509318641 1.942443716354177 0.0520834073662976 1.0 0.9086240350367574 48 O43464,Q9NUQ9,P10909,P31749,O00429,P30536,Q96A26,O60313,Q9H4A6,O14737,P42858,Q8N2A8,P49815,Q9Y6C9,P21796 15 +Skeletal system morphogenesis 0.5308288954419027 1.9381091188990216 0.0526099111662701 1.0 0.9086240350367574 21 O95470,Q9NX62,O75844,Q92896 4 +Protein localization to endoplasmic reticulum 0.5255304335644855 1.932850242672393 0.0532546489208909 1.0 0.9086240350367574 38 Q5JRA6,Q9Y5M8,Q13438,P46379,Q7L5D6,Q9NQC3,Q9UHB9,O43731,O43681,P33908,O15027,Q15629,Q96HY6,P24390 14 +Mammary gland epithelium development 0.6746107387580148 1.932080578360105 0.0533495610868575 1.0 0.9086240350367574 10 P31749,Q9Y297,Q9NQC3,P31751 4 +Protein retention in er lumen 0.7988933573533333 1.9279843569285349 0.0538570719496016 1.0 0.9086240350367574 5 O43731,P24390 2 +Maintenance of protein localization in endoplasmic reticulum 0.7988933573533333 1.9279843569285349 0.0538570719496016 1.0 0.9086240350367574 5 O43731,P24390 2 +Maintenance of protein location in cell 0.5293658316660199 1.920078401470408 0.054847997018445 1.0 0.9086240350367574 24 P52789,P31749,Q13438,P30536,O94901,O43731,Q9H4A6,Q9UH99,P24390 9 +Response to increased oxygen levels 0.6927191114847076 1.9193774677542783 0.0549365804074715 1.0 0.9086240350367574 9 P00846,Q9Y487 2 +Peptide catabolic process 0.6505043035245488 1.917895241845169 0.0551242956958379 1.0 0.9086240350367574 11 P55786,Q9NZ08 2 +Regulation of autophagy of mitochondrion 0.5979707328642739 1.916373545121386 0.0553175656660884 1.0 0.9086240350367574 15 O43464,P30536,O00429,P42858,P21796 5 +Negative regulation of ion transmembrane transport 0.5274037530302037 1.9163287947675136 0.0553232579246052 1.0 0.9086240350367574 20 P35609,P62942,P78417,P0DP25,Q9UMX0,P21796 6 +Positive regulation of necrotic cell death 0.796064154247203 1.9160016431595923 0.0553648865392284 1.0 0.9086240350367574 5 P30536 1 +Detection of biotic stimulus 0.7932521371337975 1.9040781747041553 0.0569000037008564 1.0 0.9086240350367574 5 P30536 1 +Positive regulation of establishment of protein localization to mitochondrion 0.6474669824732255 1.9014564236631837 0.0572422550513938 1.0 0.9086240350367574 11 P55786,O14737 2 +Negative regulation of leukocyte migration 0.7274382364830037 1.9011894452976028 0.057277203071993 1.0 0.9086240350367574 7 P14174,P00813,P09601,P31749 4 +Protein o linked glycosylation 0.5704851456479008 1.9011551711106265 0.0572816909190045 1.0 0.9086240350367574 17 Q9H9S5,O60502,Q9Y2G5,Q10472 4 +Regulation of endocytic recycling 0.8449826807249936 1.8971206077173872 0.0578120219634825 1.0 0.9086240350367574 4 P35609 1 +Anterior posterior axis specification 0.7263096750977376 1.8959533999251177 0.0579662068068962 1.0 0.9086240350367574 7 Q8N2A8,Q15363,Q5T9L3 3 +Anion transport 0.4378763000246248 1.8885046750868637 0.058958230887621 1.0 0.9086240350367574 73 P55011,O95563,Q96QD8,O43681,O43808,P30825,Q9HD26,P0CG08,P30536,Q9Y6M7,P21796,Q9UHG3,Q9H2D1,Q96S66,Q8TB61,O43865,Q4KMQ2,P45880,P14174,P54105,Q9UBX3,Q9C0H2 22 +Glycosyl compound biosynthetic process 0.723832499366875 1.8844508433844611 0.0595040180261658 1.0 0.9086240350367574 7 P00813 1 +Nucleobase containing small molecule biosynthetic process 0.723832499366875 1.8844508433844611 0.0595040180261658 1.0 0.9086240350367574 7 P00813 1 +Maintenance of protein localization in organelle 0.5540054853927306 1.8844011237295712 0.0595107379601413 1.0 0.9086240350367574 18 P52789,P31749,Q13438,P30536,O94901,O43731,Q9UH99,P24390 8 +Regulation of amyloid beta clearance 0.7415589387856151 1.8840487647403108 0.0595583796088747 1.0 0.9086240350367574 6 Q16850,P10909 2 +Protein import 0.3689169371367337 1.8833178840205185 0.0596573012015553 1.0 0.9086240350367574 91 P40855,O60830,Q08209,Q96P70,Q15388,Q9NS69,Q99595,O14737,O75381,O14925,P10909,P31749,O75312,O00410,Q99567,Q8N1F7,Q15648,Q13501,P12270,P49815,O95831,Q92973,P06493,Q8TEX9 24 +Regulation of erad pathway 0.7235785904032184 1.8832711017706605 0.0596636376183132 1.0 0.9086240350367574 7 P46379 1 +Myelin assembly 0.7041479198133076 1.8794288456359511 0.0601859607151151 1.0 0.9086240350367574 8 Q9NR77 1 +Cartilage development 0.5914639616127843 1.8761935718183052 0.0606287044503361 1.0 0.9086240350367574 15 Q9NX62,O75844,Q92896,Q96HY6 4 +Positive regulation of blood circulation 0.8380219129404748 1.8689958016164756 0.0616233984887073 1.0 0.9086240350367574 4 P16615,P00813,P09493 3 +Purine containing compound salvage 0.7017654362391005 1.8679413797868616 0.0617702422528223 1.0 0.9086240350367574 8 P00813 1 +Activation induced cell death of t cells 0.7828700711352257 1.859940690415016 0.0628939175911118 1.0 0.9086240350367574 5 Q9HCL2 1 +Positive regulation of heart rate 0.9295441089401976 1.858802125479244 0.0630551910914944 1.0 0.9086240350367574 3 P00813,P09493 2 +Specification of symmetry 0.699858541711437 1.85873772433699 0.0630643234793575 1.0 0.9086240350367574 8 Q15363,O94788 2 +Amyloid precursor protein metabolic process 0.5214310369193437 1.858643992071767 0.0630776171133182 1.0 0.9086240350367574 25 O75298,P62942,Q9Y287,P10909,Q96P70,O95197,Q9NQC3,Q15392,P49755 9 +Mitochondrial calcium ion homeostasis 0.6600515244579578 1.8563844299401089 0.0633987824226862 1.0 0.9086240350367574 10 Q8IYU8,Q9NWR8,Q9BPX6 3 +Endosomal transport 0.3753739033406278 1.855949174650187 0.0634608028497787 1.0 0.9086240350367574 87 O43633,Q9BVK6,Q13190,P49257,Q96D71,O95249,Q9Y5X3,Q9H3S7,O43752,O60271,Q9UNH7,Q9H223,Q13501,Q14203,Q15075,Q96C92,O60826,P35609,Q4J6C6,Q9UID3,Q4V328,O14964,Q8IUD2,Q8WUX9,Q9BRG1,Q567U6,Q96QK1,O15260 28 +Antigen processing and presentation of peptide antigen via mhc class i 0.6173648089909676 1.8558237777483633 0.0634786802125746 1.0 0.9086240350367574 12 Q9NZ08,Q6P179 2 +Intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator 0.6171735425132486 1.854736162804714 0.0636339119897064 1.0 0.9086240350367574 12 Q96RU2,P46379,P61978 3 +Regulation of notch signaling pathway 0.7348210032977349 1.8537575583451005 0.0637738529428879 1.0 0.9086240350367574 6 P57105 1 +Neuron death 0.4111095076590078 1.853479002167173 0.0638137330665475 1.0 0.9086240350367574 79 Q99720,P07196,P09601,P10909,P31751,P31749,Q96A26,Q9NR28,Q15392,Q01105,P51858,O95831 12 +Positive regulation of glucose metabolic process 0.7344800255457201 1.8522222954081464 0.0639939084878502 1.0 0.9086240350367574 6 P31751 1 +Positive regulation of cellular carbohydrate metabolic process 0.7344800255457201 1.8522222954081464 0.0639939084878502 1.0 0.9086240350367574 6 P31751 1 +Glycoprotein biosynthetic process 0.4731220489563151 1.8492578479052049 0.0644205892412124 1.0 0.9086240350367574 61 Q8WVQ1,Q9Y287,Q10472,Q8NCH0,Q2TAA5,Q99805,Q9BT22,O60476,O60502,Q9HC07,Q08379,Q9Y2G5,Q9H4A6,Q9H9S5,Q7LGA3,P33908,Q86YN1,O15294 18 +Golgi to plasma membrane transport 0.5194021589324469 1.8448971230351645 0.0650525052682238 1.0 0.9086240350367574 30 Q8TAG9,Q9H4A5,Q96A65,Q4J6C6,Q567U6,Q13439,Q9BZG1,Q9H4A6,Q9UJY4,O15027,Q15276,P50570,O60826,P98194,Q01082,Q9HD26 16 +Iron ion homeostasis 0.5618975564313194 1.8443446246054311 0.0651329319661742 1.0 0.9086240350367574 17 Q9Y487,P30519,P09601 3 +Leukocyte homeostasis 0.5863075280997233 1.8442411446427849 0.0651480045661241 1.0 0.9086240350367574 15 P31749,Q9HCL2,P49069,P00813,P14174 5 +Sarcoplasmic reticulum calcium ion transport 0.6960047306952738 1.8401121340528752 0.0657517762097965 1.0 0.9086240350367574 8 P16615,P78417,P0DP25 3 +Regulation of ryanodine sensitive calcium release channel activity 0.7313948151500009 1.8383208002992917 0.0660151478445048 1.0 0.9086240350367574 6 P78417,P0DP25 2 +Protein localization to cilium 0.5608732102408941 1.83754799752265 0.066129037626377 1.0 0.9086240350367574 17 Q7Z4L5,Q96A65,A0AVF1,Q96C92,Q8NCM8,Q10713,Q9Y5K8,Q15276 8 +Establishment of protein localization to mitochondrial membrane 0.5318525027853307 1.8329831918697328 0.0668050707138283 1.0 0.9086240350367574 19 O60220,Q9Y5J7,Q9Y5J9,Q8N8Q8,P0DP25,Q9NS69,O14737 7 +Peptidyl lysine hydroxylation 0.7120530253960049 1.829576840710134 0.067313239420609 1.0 0.9086240350367574 7 Q96AY3,Q92791 2 +Regulation of modification of synaptic structure 0.7754045659173014 1.8280917956378016 0.0675357760653818 1.0 0.9086240350367574 5 Q9UQB8,Q7L576 2 +Nucleoside triphosphate catabolic process 0.7289299605133057 1.8272013456670928 0.0676695016268507 1.0 0.9086240350367574 6 Q9H773,P00813 2 +Regulation of organic acid transport 0.6120915554696711 1.825795334782474 0.067881096307349 1.0 0.9086240350367574 12 P31749,P14174,P31751 3 +Positive regulation of ryanodine sensitive calcium release channel activity 0.9209136836253085 1.8255262548219915 0.0679216529090731 1.0 0.9086240350367574 3 P78417 1 +Collagen biosynthetic process 0.7742190632871194 1.823025897535631 0.0682994686307298 1.0 0.9086240350367574 5 P08670,Q92791 2 +Response to misfolded protein 0.6534452819721683 1.8218497579967312 0.0684777854300895 1.0 0.9086240350367574 10 P46379 1 +Hormone biosynthetic process 0.6731346625140494 1.8212826407638911 0.0685639038229999 1.0 0.9086240350367574 9 Q14849,P16435,P05023,P30536 4 +Positive regulation of carbohydrate metabolic process 0.6910634301609546 1.8161819120414713 0.0693424717940731 1.0 0.9086240350367574 8 P31751 1 +Second messenger mediated signaling 0.5159679909728044 1.8156588591802465 0.0694227186660005 1.0 0.9086240350367574 28 Q9Y4G8,P78417,P0DP25,P16615,O75844,P42858,P00813 7 +Regulation of response to extracellular stimulus 0.7720015155533126 1.8135437558251988 0.0697479963012823 1.0 0.9086240350367574 5 Q9UMX5,P80303 2 +Positive regulation of mitochondrial calcium ion concentration 0.7716595517750167 1.812080827918913 0.0699737082832081 1.0 0.9086240350367574 5 Q9BPX6 1 +Cellular response to molecule of bacterial origin 0.5148202923778595 1.8089798378897275 0.0704541357294583 1.0 0.9086240350367574 30 Q9NUQ9,P30536,Q8IXJ6,P31749,P08670 5 +Inositol lipid mediated signaling 0.5135230861040694 1.8089613964697824 0.0704570008789264 1.0 0.9086240350367574 21 P31749,Q8IXJ6,Q05086,Q8NDZ4,Q10713,P49815,O15294 7 +Deoxyribose phosphate catabolic process 0.7241125762691782 1.8054356255472923 0.0710065405602196 1.0 0.9086240350367574 6 Q9H773,P00813 2 +Exonucleolytic catabolism of deadenylated mrna 0.6500855406597803 1.8042423097522284 0.0711933292591004 1.0 0.9086240350367574 10 Q969T7 1 +Positive regulation of protein localization 0.3979088611873256 1.8025833531414612 0.0714536733340471 1.0 0.9086240350367574 146 O95563,Q9H4A5,P31751,Q9BV73,Q9NQC3,Q9Y282,O14737,Q9H3S7,Q9NR31,P31749,O75312,O00410,O00429,P33176,Q13277,P55786,Q9H4A6,Q9C0E2,P15311,O00264,Q9H6U6,P98194,Q01082,O43464,Q13501,P12270,Q66GS9,P78371,P25054,Q96C92,O75116,Q96JB5,P49755,Q96HY6,Q5T9L3,Q96D46,P35580,Q9GZY8,P06493,P50402,Q92544,P49368,Q96QK1 43 +Protein insertion into er membrane 0.5985753929702916 1.796752649921201 0.072374896443508 1.0 0.9086240350367574 13 P46379,Q7L5D6,Q96A33,O43681,P49069,Q15629 6 +Vitamin transmembrane transport 0.7047698883709632 1.7955047975081704 0.0725733090788167 1.0 0.9086240350367574 7 Q9H2D1,Q8WTV0 2 +Mitochondrion localization 0.5410379477902951 1.7951677864727424 0.0726269712407199 1.0 0.9086240350367574 18 P07196,O75153,O00429,O60313,Q8IWA4 5 +Response to arsenic containing substance 0.5982478248111602 1.794827755920773 0.0726811471120583 1.0 0.9086240350367574 13 P78417,P09601 2 +Regulation of gliogenesis 0.5540848122737835 1.7923994999574222 0.0730689948509188 1.0 0.9086240350367574 17 Q96G23,P30536 2 +Lens development in camera type eye 0.7040808871092163 1.7922759031769702 0.0730887812725669 1.0 0.9086240350367574 7 P08670 1 +Regulation of long chain fatty acid import into cell 0.8189870619309862 1.7917431760348796 0.0731741149290772 1.0 0.9086240350367574 4 P31751 1 +Lymphocyte homeostasis 0.6060156501403439 1.7910872902657344 0.0732792883966966 1.0 0.9086240350367574 12 P31749,P14174,P00813,Q9HCL2 4 +Microtubule anchoring 0.6055856850986978 1.7886267790258756 0.0736749421741218 1.0 0.9086240350367574 12 O75381,Q14203,P49841,Q15154,Q8TD16,O95684 6 +Response to testosterone 0.6053997259492958 1.7875624339736134 0.0738466307971137 1.0 0.9086240350367574 12 P30536 1 +Intraciliary transport 0.6661434060150917 1.7860384028154084 0.0740930403924524 1.0 0.9086240350367574 9 Q7Z4L5,O43805,A0AVF1,Q8NCM8 4 +Negative regulation of transporter activity 0.5530768614709113 1.7856800941494313 0.0741510702023209 1.0 0.9086240350367574 17 P35609,P62942,P78417,P0DP25,Q9UMX0 5 +Endochondral bone morphogenesis 0.765165238016711 1.7842625916695825 0.0743810058019101 1.0 0.9086240350367574 5 Q9NX62,O75844 2 +Body fluid secretion 0.564752655333125 1.7809369410142 0.0749227529126388 1.0 0.9086240350367574 16 P52789,Q13505,P61201,P00403,P16220,P00813 6 +Microtubule anchoring at microtubule organizing center 0.7185379326138833 1.7801937467322266 0.0750442584357049 1.0 0.9086240350367574 6 Q8TD16,Q14203,Q15154 3 +Centriole centriole cohesion 0.7637064718993224 1.7780048253299547 0.0754030623845942 1.0 0.9086240350367574 5 Q9BV73,Q66GS9 2 +Regulation of establishment of protein localization 0.3985909421562518 1.771824185039384 0.0764237465905828 1.0 0.9086240350367574 151 P55011,Q16836,O95563,Q9H4A5,P31751,Q08209,Q9Y282,Q15154,O43768,P49257,O14737,Q9HD26,Q16850,Q9H3S7,Q9NR31,O75312,O00410,O00429,Q6ZWJ1,Q13438,Q32P28,P55786,Q9H4A6,Q9C0E2,P15311,O95429,Q9H6U6,P98194,O43464,P49841,P12270,Q66GS9,Q96KC8,P78371,P49755,Q5T9L3,Q9BRT2,Q4V328,P35580,Q9GZY8,Q14C86,P06493,P50402,Q92544,P49368,Q96QK1 46 +Vacuolar localization 0.5509702998119876 1.7716239452736549 0.0764570021198349 1.0 0.9086240350367574 17 P09601,Q9H0B6,P33176,Q86YV9,O60271,Q9BZG1,P35579 7 +Mitochondrial electron transport ubiquinol to cytochrome c 0.7607958297926694 1.76550891211852 0.0774782737502994 1.0 0.9086240350367574 5 Q9UDW1 1 +T cell homeostasis 0.6975618724776715 1.7616783142683987 0.0781236638165867 1.0 0.9086240350367574 7 Q9HCL2 1 +Localization within membrane 0.4279303709784505 1.7611757093080276 0.0782086680113169 1.0 0.9086240350367574 209 P40855,Q9H4A5,P57105,O60220,P31751,Q9Y4G8,Q9Y5J7,Q99805,P46379,Q7L5D6,Q8N8Q8,Q9Y5J9,Q9NPA0,Q9NS69,O43681,Q9BZG1,O60725,Q96A33,Q13439,P50542,P50570,O14737,Q5VZ89,Q9HD26,P43307,Q9H9H4,Q9H3S7,P31749,P33176,O43752,Q9UHB9,Q13277,Q9H4A6,Q53H12,P15311,Q15363,O95429,Q14BN4,O00264,P98194,Q9Y5Y5,Q01082,Q9H223,Q13501,Q9BTX1,Q9HD45,O00159,Q9UJY4,O43805,Q96C92,O75116,Q15629,O60826,Q9HD20,Q15276,P35609,Q8TAG9,Q96A65,Q9NQX3,Q9UID3,Q86YV9,O14964,Q4J6C6,Q9Y5L4,P0DP25,Q4V328,P07602,Q9GZY8,P49069,O15027,Q14696,Q567U6,Q92544,Q96QK1,Q8N3R9,Q14168 76 +Atp synthesis coupled proton transport 0.600135362963705 1.7573872531577328 0.0788518245222742 1.0 0.9086240350367574 12 P00846 1 +Positive regulation of calcium ion transport 0.5212817098420905 1.7570764498135694 0.0789047792388502 1.0 0.9086240350367574 19 P78417,P0DP25,P30536 3 +Regulation of protein exit from endoplasmic reticulum 0.6602946362619229 1.7564646123169765 0.0790091087273023 1.0 0.9086240350367574 9 Q13438,Q9Y6B6,Q92544,Q9NR31 4 +Pore complex assembly 0.5824747467541 1.7564368004950135 0.0790138538167659 1.0 0.9086240350367574 14 Q9BTX1,P12270,Q9NQC3,Q8N1F7,P49368 5 +Fatty acid beta oxidation using acyl coa oxidase 0.7132018466975255 1.755977876080764 0.0790921862770246 1.0 0.9086240350367574 6 Q15067 1 +Negative regulation of cell development 0.5075323678550658 1.7543092071502142 0.0793775389895576 1.0 0.9086240350367574 24 Q96G23,Q08209,P30536,Q9Y4G8,Q8IXJ6,Q9NQC3,Q15154,O43707,Q8N0X7 9 +Peptidyl arginine methylation to asymmetrical dimethyl arginine 0.9006355400660155 1.7470485449946689 0.0806289177478143 1.0 0.9086240350367574 3 O60678 1 +Mitochondrial fragmentation involved in apoptotic process 0.7562203791469142 1.7458391948296943 0.0808388981319532 1.0 0.9086240350367574 5 O00429,Q96QK1,Q8N163,Q9GZY8 4 +Cellular response to cadmium ion 0.6941438347384485 1.7456016466871167 0.0808801959252292 1.0 0.9086240350367574 7 P09601 1 +Negative regulation of small gtpase mediated signal transduction 0.6387875066200974 1.7448182691548455 0.0810165076752595 1.0 0.9086240350367574 10 Q9NUQ9 1 +Regulation of protein secretion 0.4903753276937596 1.744760580020171 0.0810265532521592 1.0 0.9086240350367574 48 P55011,Q16836,Q16850,Q9H4A5,O95563,Q9H3S7,Q08209,O00429,Q96KC8,Q6ZWJ1,P35580,Q32P28,O43768,Q9H4A6,P15311,P49755,Q5T9L3,Q9BRT2 18 +Positive regulation of glucose import 0.7103977729039319 1.7432316796200795 0.0812931538523533 1.0 0.9086240350367574 6 P31751 1 +Deoxyribonucleoside triphosphate catabolic process 0.7555492278529 1.7429512419825826 0.0813421320918568 1.0 0.9086240350367574 5 Q9H773,P00813 2 +Lipid localization 0.3669952778851172 1.7407277841063684 0.0817313056802351 1.0 0.9086240350367574 87 Q9H6V9,Q99720,P10909,P30536,P31751,Q9UID3,P31749,Q9BQE5,Q16739,P35790,O15260,Q8WTV0 12 +Regulation of lipid transport 0.5036732460222016 1.7347933923164718 0.0827774069994795 1.0 0.9086240350367574 21 O15260,P30536,P31751 3 +Spinal cord development 0.5953622028522522 1.7299542834186827 0.0836384435144883 1.0 0.9086240350367574 12 O75312,P07196,Q14203,Q8NCM8 4 +Regulation of protein localization to centrosome 0.7517659807933766 1.7266592478730516 0.0842288785672917 1.0 0.9086240350367574 5 Q9BV73,P25054 2 +Membrane protein proteolysis 0.5854200132741401 1.7191768585171554 0.085582173221379 1.0 0.9086240350367574 13 Q9Y4W6,P35579,Q9NZ08,Q8TCT9 4 +Positive regulation of oxidoreductase activity 0.6335757822785641 1.7172971221966828 0.0859248975948341 1.0 0.9086240350367574 10 P31749,Q9P0J1,P0DP25,P16435,Q8WTV0 5 +Positive regulation of monooxygenase activity 0.704061425449057 1.7143769396794546 0.0864595208906697 1.0 0.9086240350367574 6 P16435,Q8WTV0,P0DP25,P31749 4 +Response to pain 0.7999916067264423 1.7141750956028583 0.0864965732866918 1.0 0.9086240350367574 4 P30536 1 +Behavioral response to pain 0.7999916067264423 1.7141750956028583 0.0864965732866918 1.0 0.9086240350367574 4 P30536 1 +Positive regulation of smoothened signaling pathway 0.7036448356724845 1.7124773467746242 0.0868087358047806 1.0 0.9086240350367574 6 Q9BZG1,Q8NCM8,P16435 3 +Ubiquitin dependent erad pathway 0.4994205795103877 1.7118455939700954 0.0869251271774653 1.0 0.9086240350367574 37 O95155,P46379,Q96A33,P33908,Q9UBV2,Q9UMX0 6 +Endoplasmic reticulum organization 0.4896406695085303 1.7112584122263108 0.0870334198975613 1.0 0.9086240350367574 46 Q5JRA6,Q8NHH9,O00429,P46379,Q7L5D6,O95197,Q9NQC3,Q9NPA0,Q96A33,O43681,Q15363,P49069,P49257,O15027,Q12981,Q15629,Q9P2W9 17 +Regulation of autophagy 0.3621436739958859 1.7107284267112328 0.0871312575116576 1.0 0.9086240350367574 99 Q8TBX8,P42858,Q9Y5X3,Q07820,P30536,P31749,O00429,Q08379,Q93050,Q9UNH7,P19474,P21796,Q86UE4,O43464,P09601,Q9Y487,Q9UMX0,P49815,Q96A65,Q8IXJ6,Q9NNW5,P07602,O75844,P09429,Q9Y5K8 25 +Mitochondrial membrane organization 0.4864682670102745 1.7100026340202372 0.0872653859707037 1.0 0.9086240350367574 48 O60220,Q9Y4W6,Q13505,Q9Y5J7,Q9Y5J9,Q8N8Q8,Q9NS69,O60313,P50542,O14737,P52789,O95202,Q53H12,P49841,Q5HYI7,Q9NX63,P45880,P17152,P0DP25,Q8IWA4 20 +Chloride transmembrane transport 0.7476179606407065 1.7087718246860837 0.0874932236963572 1.0 0.9086240350367574 5 P55011,Q9UHG3 2 +Positive regulation of mitochondrial translation 0.7022346524602354 1.7060448300615807 0.0879997331834698 1.0 0.9086240350367574 6 Q9Y2R0,Q567V2,Q9BRT2 3 +Regulation of heart rate 0.5829205427516615 1.7043760536609394 0.0883108546756008 1.0 0.9086240350367574 13 P16615,P00813,P0DP25,P09493 4 +Vesicle mediated transport to the plasma membrane 0.4655867800099157 1.70030216323975 0.0890741037653968 1.0 0.9086240350367574 58 Q9H4A5,Q13439,Q9BZG1,P50570,Q9HD26,Q9H3S7,O43752,Q13277,Q9H4A6,P98194,Q8IWJ2,Q01082,Q9H223,Q96L92,Q9UJY4,Q96C92,O60826,Q15276,P35609,Q8TAG9,Q96A65,Q4J6C6,Q9UID3,Q4V328,O15027,Q567U6,Q96QK1,Q9UPN3 28 +Smad protein signal transduction 0.666933963999369 1.6985613147294405 0.0894018706673556 1.0 0.9086240350367574 8 P08670,Q8N1F7,Q01082 3 +Lipoprotein biosynthetic process 0.5897690828003772 1.6977214592274106 0.0895603456073108 1.0 0.9086240350367574 12 Q16739 1 +Respiratory chain complex iii assembly 0.6838331809511009 1.6969680458996126 0.0897027019077039 1.0 0.9086240350367574 7 Q6DKK2,Q69YU5,Q9BRT2,Q9BSK2 4 +Regulation of protein targeting 0.500546222188389 1.6968319172949724 0.0897284426215905 1.0 0.9086240350367574 26 P55786,O43464,O14737,P31751 4 +Cellular metabolic compound salvage 0.6098730287211638 1.6957807200277413 0.0899274150408619 1.0 0.9086240350367574 11 Q13126,Q9BV57,P00813 3 +Negative regulation of transport 0.3815942786659848 1.6957422426019062 0.0899347048464263 1.0 0.9086240350367574 83 P35609,Q16836,Q16850,P62942,P09601,P31751,P31749,Q08209,P78417,P30533,P0DP25,Q7L576,Q9UMX0,P21796,P00813 15 +Regulation of camp dependent protein kinase activity 0.6999427932114124 1.6955831263622954 0.0899648555325951 1.0 0.9086240350367574 6 Q9Y4G8 1 +Positive regulation of calcium ion transport into cytosol 0.6661461215744322 1.694700214303961 0.0901323050083395 1.0 0.9086240350367574 8 P78417,P0DP25 2 +Positive regulation of release of sequestered calcium ion into cytosol 0.6661461215744322 1.694700214303961 0.0901323050083395 1.0 0.9086240350367574 8 P78417,P0DP25 2 +Embryonic heart tube development 0.6995097831292536 1.6936055259055809 0.0903402673058195 1.0 0.9086240350367574 6 Q15363,Q15648 2 +Golgi ribbon formation 0.6825601875639128 1.690949477964144 0.0908464522901195 1.0 0.9086240350367574 7 Q9Y3A6,O43752,Q08379,Q9H4A6 4 +Protein localization to plasma membrane 0.3553439898458299 1.690377359542729 0.0909557836506191 1.0 0.9086240350367574 91 Q9H4A5,P31751,Q9Y4G8,Q13439,Q9BZG1,Q5VZ89,Q9HD26,P31749,P33176,Q13277,Q9H4A6,Q15363,P15311,Q14BN4,O00264,P98194,Q01082,Q13501,Q9UJY4,O75116,P35609,Q4J6C6,Q4V328,O15027,Q8N3R9 25 +Response to progesterone 0.7431307078707555 1.6893930956022412 0.0911441232615626 1.0 0.9086240350367574 5 P30536 1 +Cellular iron ion homeostasis 0.5801121833251597 1.6877231522710858 0.0914643853109147 1.0 0.9086240350367574 13 Q9Y487,P09601 2 +Aggrephagy 0.7934236794427021 1.6872511542789894 0.0915550689494479 1.0 0.9086240350367574 4 Q9UMX0,P42858 2 +Regulation of fatty acid transport 0.7415388427111222 1.682511447503642 0.0924697070061231 1.0 0.9086240350367574 5 P31751,P31749 2 +Meiosis i cell cycle process 0.5108871164498192 1.681952909947779 0.0925779715789716 1.0 0.9086240350367574 19 P46379,Q92791 2 +Negative regulation of protein secretion 0.6446376641070137 1.6769090793595551 0.0935602624369771 1.0 0.9086240350367574 9 Q16836,Q16850 2 +Walking behavior 0.7908859907528103 1.6768347757022122 0.0935747953957901 1.0 0.9086240350367574 4 O75844 1 +Growth plate cartilage development 0.8825384951486221 1.6766939120870386 0.0936023517036652 1.0 0.9086240350367574 3 O75844 1 +Bone growth 0.8825384951486221 1.6766939120870386 0.0936023517036652 1.0 0.9086240350367574 3 O75844 1 +Embryonic digestive tract development 0.7905846593717236 1.675597414095762 0.0938170756713376 1.0 0.9086240350367574 4 P00813 1 +Phosphatidylethanolamine metabolic process 0.790546587758971 1.6754410726181288 0.093847723715732 1.0 0.9086240350367574 4 Q9HBU6,P35790 2 +Regulation of intrinsic apoptotic signaling pathway in response to dna damage 0.6055628682148235 1.671949333592837 0.0945343134470735 1.0 0.9086240350367574 11 Q8N163,P10909,P61978,Q96K76,P14174 5 +Maintenance of protein location 0.4960570586858199 1.6699707141213025 0.0949251579862588 1.0 0.9086240350367574 34 P52789,P31749,Q13438,P30536,O94901,Q7L5D6,O43731,Q9UN86,Q9H4A6,Q9UH99,O60826,Q9HD26,P24390 13 +Mitochondrial atp synthesis coupled proton transport 0.6051866191268965 1.6698666783312337 0.0949457443601919 1.0 0.9086240350367574 11 P00846 1 +Endoplasmic reticulum membrane organization 0.6609674900193664 1.6692891096226214 0.0950600974466515 1.0 0.9086240350367574 8 Q15363,Q8NHH9,Q9P2W9,Q9NQC3 4 +Negative regulation of autophagy of mitochondrion 0.7886790165104296 1.6677698319262255 0.0953614267876288 1.0 0.9086240350367574 4 P30536 1 +Fatty acid transmembrane transport 0.6605347840310161 1.6671634141135552 0.0954819154202692 1.0 0.9086240350367574 8 P31751,P31749 2 +Negative regulation of protein polymerization 0.4966423633550522 1.6665094085764245 0.0956119958157311 1.0 0.9086240350367574 26 Q13045,Q9BPX3,Q13813,Q9NUQ9,P35611,P16949,P35612,Q9UEY8,Q02790,O15020,Q01082,P45880 12 +Early endosome to golgi transport 0.659730806582213 1.6632128328338651 0.0962698397550816 1.0 0.9086240350367574 8 P49257,Q9BVK6,Q13190,O15260 4 +Negative regulation of lipid localization 0.7874105354729033 1.6625571504625576 0.0964011144338958 1.0 0.9086240350367574 4 P31751 1 +Maintenance of protein location in mitochondrion 0.7871527056095751 1.6614974048315267 0.0966135896988946 1.0 0.9086240350367574 4 P31749,P30536 2 +Positive regulation of smooth muscle cell proliferation 0.6590793445400076 1.660010738616973 0.0969122922357341 1.0 0.9086240350367574 8 P09601 1 +Glycosphingolipid biosynthetic process 0.7867184183270344 1.6597122055138538 0.0969723627689593 1.0 0.9086240350367574 4 Q16739 1 +Deoxyribonucleoside triphosphate metabolic process 0.6582908632744214 1.6561340369238249 0.0976946778353662 1.0 0.9086240350367574 8 Q9H773,P00813 2 +Response to corticosterone 0.8771253056594717 1.6555966703579406 0.0978035249318969 1.0 0.9086240350367574 3 P07196 1 +Sulfur amino acid biosynthetic process 0.7349500202511365 1.6539897756281752 0.0981295901396794 1.0 0.9086240350367574 5 Q13126,Q9BV57,Q99707 3 +Nucleotide transmembrane transport 0.6394919746615243 1.6506438780476025 0.0988113137265473 1.0 0.9086240350367574 9 Q9H2D1,O43808,Q8TB61 3 +Positive regulation of muscle contraction 0.6738461524752055 1.649669757825338 0.0990104988540232 1.0 0.9086240350367574 7 P78417 1 +Positive regulation of toll like receptor signaling pathway 0.7337820829275766 1.6489277085476144 0.0991624457641213 1.0 0.9086240350367574 5 Q9NQC3 1 +Midbrain development 0.4915899523070683 1.6431860689716011 0.1003444413268883 1.0 0.9086240350367574 21 Q8IXJ6,P0DP25,O14949,O15027,Q5T9L3 5 +Long chain fatty acid import across plasma membrane 0.8735903026135909 1.6418072587172028 0.1006299542829389 1.0 0.9086240350367574 3 P31751 1 +Regulation of long chain fatty acid import across plasma membrane 0.8735903026135909 1.6418072587172028 0.1006299542829389 1.0 0.9086240350367574 3 P31751 1 +Protein hydroxylation 0.5536067256639001 1.6394153498487471 0.1011267869784182 1.0 0.9086240350367574 15 P13674,Q92791,Q96AY3,Q32P28,O75718,Q8IVL6 6 +Double strand break repair via break induced replication 0.6546933785833609 1.6384308896109148 0.1013318398238123 1.0 0.9086240350367574 8 P25205,O75419,P33993,Q9BRT9,P33991 5 +Negative regulation of type i interferon mediated signaling pathway 0.6872823079743652 1.6376293401942676 0.1014990387016454 1.0 0.9086240350367574 6 Q7Z739,Q14166,Q9UIV1,Q9Y3Z3 4 +Response to mineralocorticoid 0.6708989047375424 1.6356769332186956 0.1019072195801582 1.0 0.9086240350367574 7 O95831,P07196 2 +Regeneration 0.4923857585040373 1.6345219130818365 0.1021493088969951 1.0 0.9086240350367574 32 P10586,Q7Z4V5,Q99707,P30536,Q08209,P09601,Q96G23,P07196,P00374,Q15648 10 +Blood vessel endothelial cell migration 0.4918191457112831 1.6335700784324496 0.1023491548599071 1.0 0.9086240350367574 24 P09601,P31749,P35579,P06576,P09429,P42785,Q8WTV0 7 +Anion transmembrane transport 0.48231022147875 1.6241425226093755 0.1043453944724368 1.0 0.9086240350367574 44 P55011,Q9H2D1,O95563,Q8TB61,Q9Y6M7,O43808,P30825,Q9UHG3,P21796,Q9UBX3,Q9HD26,P45880 12 +Positive regulation of glucose transmembrane transport 0.6682387312048452 1.6230338202284642 0.1045821753249023 1.0 0.9086240350367574 7 P31751 1 +Negative regulation of cell population proliferation 0.3624054266352667 1.6210316591774911 0.10501084910792 1.0 0.9086240350367574 109 Q99627,P09601,Q96G23,P30536,Q8IXJ6,P57105,Q9NR77,O94788,P25054,Q96DY7,Q9Y4G8,Q32P28,Q15392,P50402,O14737,P09493,P49815,Q8IVL6 18 +Positive regulation of cation channel activity 0.6330491515035279 1.617677857133394 0.1057320403957082 1.0 0.9086240350367574 9 P78417,P0DP25,P42858 3 +Mitochondrial fission 0.5682211422883614 1.6169491173139183 0.1058892647813405 1.0 0.9086240350367574 13 Q9NUQ9,O00429,Q9GZY8,O60313,Q9UDX5,Q96QK1 6 +Positive regulation of macroautophagy 0.4873801197164047 1.6162171753396477 0.1060473666224821 1.0 0.9086240350367574 20 P49815,P21796,P09601,P42858 4 +Transition metal ion transport 0.5676939001685383 1.6138014199130384 0.1065705064818964 1.0 0.9086240350367574 13 O15173,Q9HC07,P50570,Q9HD20,P98194,Q8NEW0 6 +Positive regulation of protein exit from endoplasmic reticulum 0.7239226839293619 1.6061220111266767 0.1082471045143893 1.0 0.9086240350367574 5 Q92544,Q9NR31 2 +Negative regulation of protein containing complex assembly 0.4842912784557008 1.6054132879943492 0.108402882021696 1.0 0.9086240350367574 40 Q13045,Q9BPX3,Q13813,Q9NUQ9,P35611,P10909,P49841,P35612,P16949,Q8IXJ6,Q9UEY8,P09429,P50542,O15020,Q15058,Q96QK1,Q01082,P45880 18 +Membrane lipid biosynthetic process 0.4884281459454735 1.602479535552322 0.1090496093366311 1.0 0.9086240350367574 26 Q16739,Q06136,Q96G23 3 +Cerebellar purkinje cell layer development 0.6298403442372372 1.6012270413583194 0.1093266415985052 1.0 0.9086240350367574 9 Q7Z4L5,O14949,O15020 3 +Negative regulation of intrinsic apoptotic signaling pathway in response to dna damage 0.6470352685956073 1.600662508346692 0.109451689320867 1.0 0.9086240350367574 8 Q96K76,P10909,P14174 3 +Tail anchored membrane protein insertion into er membrane 0.6116117892092342 1.6005914944288764 0.109467427367486 1.0 0.9086240350367574 10 O43681,P46379,Q7L5D6,P49069 4 +Cellular response to biotic stimulus 0.4851776886576121 1.5994921127706616 0.1097112997366216 1.0 0.9086240350367574 38 Q9NUQ9,P30536,P31749,Q8IXJ6,P08670,O75844,Q8WTV0 7 +Phosphatidylinositol 3 kinase signaling 0.5243685231879475 1.5926740177241303 0.1112333391932134 1.0 0.920076519058758 17 P31749,Q8IXJ6,Q05086,Q8NDZ4,P49815 5 +Endothelial cell proliferation 0.484159728182811 1.5865331427761666 0.1126184200342563 1.0 0.921334910772272 21 O94788,P09601,P57105,P31749 4 +Receptor localization to synapse 0.5628998485833123 1.585144033480392 0.1129336129182847 1.0 0.9213410156153634 13 P57105,P33176,Q4V328,Q13277,Q96QK1,Q14168 6 +Ion transport 0.4200082187563963 1.5851011454515167 0.1129433553872765 1.0 0.9213410156153634 219 P55011,Q70HW3,O95563,P62942,Q08209,Q9Y4W6,Q96QD8,Q13423,O43681,O43808,P30825,P42858,Q8NEW0,Q9HD26,Q9BPX6,P00846,O43772,P0CG08,P05023,P30536,O75964,Q9UDW1,P31749,Q9HC07,P78417,Q9Y6M7,O00429,O15173,Q8IYU8,Q9UNH7,P06576,O43707,Q14BN4,P98194,P21796,Q9UHG3,Q9H2D1,Q96S66,Q8TB61,O43865,Q13555,P00403,P61201,P33176,Q4KMQ2,Q99996,P13073,Q9HD20,Q9UMX0,P45880,P35609,P14174,Q9NWR8,Q6P4Q7,P0DP25,P16615,O75844,P54105,Q9UBX3,Q9C0H2,Q6P4A7 61 +T cell differentiation in thymus 0.5898368818594594 1.5845918594277502 0.1130590957276531 1.0 0.9213410156153634 11 P00813 1 +Regulation of mitochondrial gene expression 0.5887770096262849 1.5786821369715476 0.114408984102855 1.0 0.9279227738234104 11 Q9Y2R0,Q567V2,Q07021,P42704,Q9BRT2 5 +Glial cell differentiation 0.4745603126822866 1.5783273723480284 0.1144904206832095 1.0 0.9279227738234104 46 Q96P11,Q7Z4L5,P10909,P31751,Q8IXJ6,P08670 6 +Intrinsic apoptotic signaling pathway in response to dna damage 0.4850170417730144 1.575802567122326 0.115071310609544 1.0 0.9283504354050952 26 O43464,P09601,P10909,Q96RU2,P46379,P61978,Q96K76,P14174 8 +Purine deoxyribonucleoside triphosphate metabolic process 0.8564994542227582 1.5750144796763703 0.1152531023472649 1.0 0.9283504354050952 3 P00813 1 +Nucleotide transport 0.5683137301188215 1.5732384227262524 0.1156636215837716 1.0 0.9283504354050952 12 Q9H2D1,O43808,Q8TB61 3 +Embryonic appendage morphogenesis 0.5605162116192256 1.570871375501368 0.1162125287047315 1.0 0.9283504354050952 13 Q9NX62,O94788,P42892,Q8NCM8,Q15648 5 +Regulation of phosphatase activity 0.4810374237176572 1.5679868057792892 0.11688421159793 1.0 0.9283504354050952 20 P62942,P0DP25,O95429,O75116,Q96JB5,P42858 6 +Protein localization to phagophore assembly site 0.6720110415904557 1.5673772202472172 0.1170265453253869 1.0 0.9283504354050952 6 P53365,Q5MNZ6 2 +Protein demannosylation 0.8544677377947549 1.567061751901981 0.1171002582785869 1.0 0.9283504354050952 3 P33908 1 +Protein import into peroxisome matrix 0.7636261743591494 1.5644986123193465 0.1177005186064632 1.0 0.9304817314235831 4 O75381,P50542 2 +Regulation of muscle contraction 0.4827299620222879 1.5632233028849214 0.118000080879653 1.0 0.9317354056554684 24 P78417,P0DP25,P00813,P09493 4 +I kappab phosphorylation 0.7134841845120705 1.5606659971682706 0.1186025780829975 1.0 0.9332371944511432 5 Q96HY6,P31749 2 +Regulation of synaptic vesicle exocytosis 0.5853509387250776 1.559560361052175 0.118863809918992 1.0 0.9332371944511432 11 Q06787,P49841,Q4J6C6,O14936,P0DP25,P16615 6 +Positive regulation of protein localization to cell surface 0.7130243773212079 1.5586606366218525 0.1190767230931904 1.0 0.9332371944511432 5 Q92544,Q13277,P31749 3 +Regulation of water loss via skin 0.6698311004315454 1.5573196730601977 0.1193946068601956 1.0 0.9332371944511432 6 Q16739 1 +Regulation of cardiac muscle contraction by calcium ion signaling 0.6541306036214519 1.555779145855072 0.1197606187189423 1.0 0.9332371944511432 7 P78417,P0DP25 2 +Cellular response to zinc ion 0.851544545851678 1.5556152822511582 0.1197996025174279 1.0 0.9332371944511432 3 P30536 1 +Golgi vesicle transport 0.3779794574172589 1.5540722906311657 0.1201671739261496 1.0 0.9332371944511432 142 Q9H4A5,Q9BVK6,Q9Y282,Q13439,Q9BZG1,Q8TBA6,Q13190,P49257,Q12981,P50570,P42858,Q9HD26,P24390,Q5JRA6,O95249,Q8NHH9,Q9NR31,O43752,Q9Y3A6,Q08379,Q8TD16,Q92572,Q9H4A6,Q15363,O95070,P98194,O15126,Q01082,O60749,O43731,Q9UJY4,O60826,Q15437,P35606,Q9P2W9,Q15276,P49755,Q8TAG9,Q96A65,Q4J6C6,Q9UID3,O60763,O15027,Q567U6,Q9Y6B6,Q9UPN3,O15260,Q96PC5 48 +Positive regulation of intracellular protein transport 0.4526884246879479 1.553107398817501 0.1203974788033597 1.0 0.933594574816092 57 P31751,Q9Y282,Q15154,O14737,Q9NR31,O75312,O00410,P55786,Q9C0E2,Q9H6U6,O43464,P49841,P12270,O00159,Q9GZY8,P06493,P50402,Q92544,Q9Y6B6 19 +Phosphatidylethanolamine biosynthetic process 0.8507992895204224 1.5526962703892448 0.1204957137718454 1.0 0.933594574816092 3 Q9HBU6,P35790 2 +Regulation of t cell apoptotic process 0.6677918249753402 1.5479047947357014 0.1216452200798885 1.0 0.9353466902932296 6 P00813 1 +Regulation of postsynaptic membrane potential 0.5477764655473063 1.543935118081971 0.1226040514566595 1.0 0.9353466902932296 14 Q9UQB8,P31749,Q14168 3 +Chemical synaptic transmission postsynaptic 0.5477764655473063 1.543935118081971 0.1226040514566595 1.0 0.9353466902932296 14 Q9UQB8,P31749,Q14168 3 +Positive regulation of protein localization to centrosome 0.7586451201010207 1.5438916796947155 0.1226145760832959 1.0 0.9353466902932296 4 Q9BV73,P25054 2 +Negative regulation of posttranscriptional gene silencing 0.7089227707098051 1.540761296314638 0.1233748923401734 1.0 0.9353466902932296 5 O75844 1 +Natural killer cell activation 0.6347840698103515 1.5400173932571934 0.1235561137857095 1.0 0.9353466902932296 8 P46379 1 +Gdp metabolic process 0.7067535545023621 1.5312870524935749 0.1256984640670229 1.0 0.9353466902932296 5 O14936,Q14168,Q9UDY2,Q00013 4 +N glycan processing 0.7061669148903104 1.5287239417141 0.1263328944437809 1.0 0.9353466902932296 5 P33908 1 +Regulation of ire1 mediated unfolded protein response 0.6634074074074072 1.5276426888731285 0.1266012766952009 1.0 0.9353466902932296 6 P57088,P18031,Q92905,Q07812,Q96HY6 5 +Organelle fusion 0.4659823240968347 1.5263278289859563 0.1269282413716745 1.0 0.9353466902932296 48 O95249,Q8IWA4,P31751,Q9Y4W6,O43752,O95721,Q13277,Q9GZY8,O60763,O60313,Q9BZG1,Q15075,Q9NX63,Q13190,Q12981,Q8N2A8,Q9Y6C9 17 +Lipoprotein localization 0.7055722292004343 1.5261252850931293 0.1269786660909009 1.0 0.9353466902932296 5 Q5JRA6,O15260,A6NIH7 3 +Angiotensin activated signaling pathway 0.754196253575544 1.5254677263379706 0.12714247741527 1.0 0.9353466902932296 4 P35609,O43865 2 +Calcium ion transport 0.4430743231508733 1.52510719210312 0.1272323636358754 1.0 0.9353466902932296 60 P62942,Q08209,Q9Y4W6,P42858,Q9BPX6,P30536,O00429,Q9HC07,P78417,Q8IYU8,P98194,P21796,P61201,Q13555,Q9UMX0,P0DP25,P16615,O75844,Q9NWR8 19 +Release of cytochrome c from mitochondria 0.5022228386347831 1.5239846649879425 0.1275125419812426 1.0 0.9353466902932296 18 P10909,P31749,O00429,Q96A26,O60313,O14737 6 +Skeletal muscle cell differentiation 0.6314048459105723 1.5232435971826928 0.1276977724438377 1.0 0.9353466902932296 8 Q9BYT8,P61201,P50402,Q9BRT2 4 +Establishment of protein localization to endoplasmic reticulum 0.4772343733160944 1.520522680586297 0.1283796628810092 1.0 0.9353466902932296 24 Q15629,P46379,P33908 3 +Protein transport to vacuole involved in ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway 0.8420362842649705 1.5183512245807191 0.1289258806660291 1.0 0.9353466902932296 3 Q9BRG1 1 +Amyloid beta metabolic process 0.543423701010371 1.517025667564643 0.1292602036931569 1.0 0.9353466902932296 14 O75298,P10909,O95197,Q9NQC3,P13798,P49755 6 +Regulation of production of small rna involved in gene silencing by rna 0.6610084721096118 1.5165448570084936 0.1293816367613964 1.0 0.9353466902932296 6 O75844 1 +Negative regulation of lipid transport 0.8410678969965095 1.514553443089046 0.1298855300044288 1.0 0.9353466902932296 3 P31751 1 +Protein exit from endoplasmic reticulum 0.4763351505522828 1.5135243255566495 0.1301465269702606 1.0 0.9353466902932296 24 Q9NR31,Q8TCT9,Q13438,Q9BVK6,Q92544,P49257,O15027,Q9UBV2,Q9Y6B6,O15260 10 +Chondrocyte differentiation 0.6124654284061535 1.5117963996695234 0.130585665613981 1.0 0.9353466902932296 9 Q9NX62,Q92896 2 +Calmodulin dependent kinase signaling pathway 0.8402988775068159 1.5115372216095548 0.1306516326849935 1.0 0.9353466902932296 3 O75844 1 +Response to l glutamate 0.7508247870428825 1.5114943625919584 0.1306625438297448 1.0 0.9353466902932296 4 Q9UQB8 1 +Somatic diversification of immune receptors via somatic mutation 0.7019540395752306 1.510306165615133 0.1309653192097166 1.0 0.9353466902932296 5 Q9UQ84,Q9Y3Z3 2 +Regulation of modification of postsynaptic structure 0.7503278442031309 1.5094339449614596 0.1311879238603808 1.0 0.9353466902932296 4 Q9UQB8 1 +Negative regulation of ion transport 0.4749367396893804 1.5064828745834258 0.1319432601375854 1.0 0.9353466902932296 23 P35609,P78417,P0DP25,Q9UMX0,P21796 5 +O glycan processing 0.7002369668246382 1.5027940121719583 0.1328921705018075 1.0 0.9353466902932296 5 Q9H488,Q10471,Q86SF2,Q10472 4 +Vesicle cargo loading 0.5489895843686112 1.5016368584917712 0.1331909188742086 1.0 0.9353466902932296 13 Q9NR31,Q15363,Q15437,P49755,Q96PC5 5 +Purine deoxyribonucleotide metabolic process 0.7475836693183525 1.4980525273738905 0.1341196037027454 1.0 0.9353466902932296 4 P00813 1 +Embryonic axis specification 0.6568790209320551 1.4974230751466804 0.1342832077835689 1.0 0.9353466902932296 6 Q8N2A8,Q15363 2 +Cytoplasm organization 0.835997631734754 1.4946621409683598 0.1350026395376027 1.0 0.9353466902932296 3 Q8N2A8,P33176 2 +Porphyrin containing compound metabolic process 0.4980013435778353 1.494158332477242 0.1351342404432265 1.0 0.9353466902932296 18 P30519,P30536 2 +Macroautophagy 0.3521433982083491 1.4922000943091611 0.1356466976539743 1.0 0.9353466902932296 107 O43633,Q5MNZ6,Q8TBX8,P42858,Q9Y5X3,P31749,O95721,Q93050,Q9UNH7,P21796,Q9Y4P1,O43464,Q9Y6I9,P53365,Q13501,P09601,Q9Y487,Q9UMX0,P49815,Q96HY6,Q96A65,O14681,O14964,P16615,Q8WUX9,Q9Y5K8,Q9BRG1 27 +Protein localization to extracellular region 0.4093865385865962 1.4902961398619994 0.1361463870258454 1.0 0.9353466902932296 71 P55011,Q16836,Q9H4A5,O95563,Q08209,O43768,Q9UBV2,Q5JRA6,Q16850,Q7Z7E8,Q9H3S7,O00429,Q6ZWJ1,Q32P28,Q9H4A6,P15311,Q96KC8,Q13555,P49755,Q9BRT2,Q5T9L3,Q86YV9,P35580,Q96PC5 24 +Fat cell differentiation 0.4742390032902224 1.4877248819344826 0.1368234629103251 1.0 0.9353466902932296 32 P31749,P31751,Q8IXJ6,Q9NZ08,Q86X55,Q8N4Q0 6 +Negative regulation of protein dephosphorylation 0.5534053352413343 1.4860137564484173 0.1372754823652924 1.0 0.9353466902932296 12 P62942,O43768,O75116 3 +Positive regulation of response to endoplasmic reticulum stress 0.5898629916338688 1.4839699340490924 0.1378168970636775 1.0 0.9353466902932296 10 P46379 1 +Non motile cilium assembly 0.5076485549607802 1.4789369037165256 0.1391571790731975 1.0 0.9353466902932296 17 Q9BV73,Q66GS9,Q15555,Q15154,Q9P2S5,Q8WXW3,Q8NCM8,P50570 8 +Manganese ion transport 0.8315571343990423 1.477232656253479 0.1396132828680745 1.0 0.9353466902932296 3 Q9HD20,Q9HC07 2 +Manganese ion transmembrane transport 0.8315571343990423 1.477232656253479 0.1396132828680745 1.0 0.9353466902932296 3 Q9HD20,Q9HC07 2 +Protein targeting to membrane 0.4699064815119411 1.4767438959614825 0.1397443007273304 1.0 0.9353466902932296 39 O60725,P46379,P43307,P31751 4 +Ventral spinal cord development 0.7419379521948799 1.4746188194195706 0.1403150524106173 1.0 0.9353466902932296 4 Q8NCM8 1 +Peptidyl proline hydroxylation 0.6211618578063925 1.4722854567951946 0.1409438088758059 1.0 0.9353466902932296 8 P13674,P07237,Q32P28,O75718,Q8IVL6 5 +Regulation of calcium ion transmembrane transporter activity 0.5065210139874915 1.471235546153019 0.1412274272412716 1.0 0.9353466902932296 17 Q9UMX0,P78417,P0DP25,P42858 4 +Glycoprotein metabolic process 0.410802102391878 1.4712155749382638 0.1412328264277873 1.0 0.9353466902932296 70 Q9Y287,Q9NX62,Q99805,Q9BT22,O60502,O60476,Q9HC07,Q08379,Q9H4A6,P33908,Q86YN1,O15294,Q8NCH0,Q2TAA5,Q9Y2G5,Q8WVQ1,Q10472,Q9H9S5,Q7LGA3 19 +Chromosome organization involved in meiotic cell cycle 0.4947371234310708 1.4710561201885666 0.1412759404587544 1.0 0.9353466902932296 18 P46379,Q92791 2 +Positive regulation of mitochondrion organization 0.4703555906680535 1.4709326322449234 0.1413093365862376 1.0 0.9353466902932296 23 O43464,O00429,Q96A26,O14737,P42858,Q8N2A8,P21796 7 +Negative regulation of cysteine type endopeptidase activity 0.4685282327946086 1.4666162245422671 0.1424804839148241 1.0 0.9353466902932296 21 P31749,P78318,Q15392,P16435,Q15418,Q96K76 6 +Autophagy of mitochondrion 0.4715051559325795 1.46549014825097 0.1427872382745338 1.0 0.9353466902932296 32 O43464,P53365,Q5MNZ6,Q13501,P52789,P30536,O00429,P42858,P49815,P21796 10 +Face development 0.6034201878932963 1.4650196224331793 0.1429155642293516 1.0 0.9353466902932296 9 O95470 1 +Regulation of cell projection size 0.7387228581042989 1.4612635749146106 0.1439431219706262 1.0 0.9353466902932296 4 P07196 1 +Collagen metabolic process 0.5678016571566568 1.461194622853963 0.1439620382879067 1.0 0.9353466902932296 11 Q8IVL6,P08670,Q32P28,Q92791 4 +Regulation of heart contraction 0.4704185852900037 1.4610963459844046 0.1439890028713162 1.0 0.9353466902932296 26 P78417,P0DP25,P16615,P09493,P00813 5 +Regulation of neuron projection regeneration 0.7384638271890777 1.4601872701331544 0.1442386129402788 1.0 0.9353466902932296 4 Q96G23 1 +Muscle structure development 0.3447077621701414 1.460092556244672 0.1442646381327956 1.0 0.9353466902932296 99 P62942,Q7Z4V5,Q08209,Q9Y4W6,P12814,P31749,O60271,O43707,Q15648,P67809,Q92990,P61201,P32929,P09493,Q96PU8,P60660,P16220,Q9BRT2,P35609,Q9BYT8,Q7Z406,Q8IXJ6,P16615,O75844,P35579,P50402 26 +Smoothened signaling pathway 0.4688752088071994 1.459428322162837 0.144447255489803 1.0 0.9353466902932296 23 Q7Z4L5,Q2M1P5,A0AVF1,Q9BZG1,O43805,P16435,Q8NCM8,Q9Y297 8 +Positive regulation of calcium ion transmembrane transporter activity 0.6022853673720756 1.4591411663904268 0.1445262578318606 1.0 0.9353466902932296 9 P78417,P0DP25 2 +Gliogenesis 0.429165048288846 1.4581500971290926 0.1447991753385478 1.0 0.9353466902932296 63 Q96P11,Q7Z4L5,P10909,P30536,P31751,Q96G23,Q8IXJ6,Q9NQC3,P08670 9 +Regulation of skeletal muscle adaptation 0.8265245707519212 1.457470448281845 0.1449865630019036 1.0 0.9353466902932296 3 P16615,Q08209 2 +Skeletal muscle adaptation 0.8265245707519212 1.457470448281845 0.1449865630019036 1.0 0.9353466902932296 3 P16615,Q08209 2 +Ventricular cardiac muscle tissue development 0.60184041482201 1.456835702158377 0.1451617381355676 1.0 0.9353466902932296 9 O75844,P62942,P09493 3 +Microtubule organizing center localization 0.5248342869760821 1.4563535500376017 0.1452949091830662 1.0 0.9353466902932296 15 P33176,O94901,Q8TD16,P15311,Q99996,Q8WXH0,Q13257 7 +Negative regulation of cell projection organization 0.4704107999105844 1.4557661019263972 0.1454572895416619 1.0 0.9353466902932296 31 Q96G23,Q9Y4G8,Q9NR77,Q9NQC3,Q05086,P08670,Q86X55 7 +Intracellular distribution of mitochondria 0.8259325044404795 1.4551449279525308 0.1456291434045338 1.0 0.9353466902932296 3 O00429,O75153 2 +Negative regulation of muscle cell apoptotic process 0.737087513076774 1.4544677618223845 0.1458166651008836 1.0 0.9353466902932296 4 P09601 1 +Neuron apoptotic process 0.4534626188075624 1.453509752546082 0.1460822738871459 1.0 0.9353466902932296 51 Q99720,Q07820,P07196,P09601,P31751,O75312,Q96A26,P48681,Q9NR28,O95831,Q01105,P51858,Q15058,Q15233 14 +Negative regulation of actin filament polymerization 0.466416636519871 1.450347189264862 0.1469617259955957 1.0 0.9357129548216688 21 Q13045,Q9BPX3,Q13813,Q9NUQ9,P35611,P35612,Q9UEY8,O15020,Q01082 9 +Positive regulation of release of cytochrome c from mitochondria 0.6305346700325267 1.4426024921441964 0.1491324809481371 1.0 0.9362432705880748 7 O00429,Q96A26,O14737 3 +Sulfur compound transport 0.5985495122847788 1.4397744097634937 0.1499312334098648 1.0 0.9362432705880748 9 Q70HW3 1 +Negative regulation of autophagy 0.4681337093033076 1.438942743376157 0.1501667457957156 1.0 0.9362432705880748 28 P09601,P30536,P31749,Q8IXJ6,Q08379,Q9NNW5,P49815 7 +Positive regulation of chemokine production 0.6141845160296324 1.4374816305066933 0.1505811887164436 1.0 0.9362432705880748 8 P09601,P14174 2 +Transition metal ion homeostasis 0.4663810138019755 1.435852827623887 0.1510442238796665 1.0 0.9362432705880748 24 Q9Y487,P30519,P09601 3 +Negative regulation of peptidyl threonine phosphorylation 0.8204655384751501 1.4336669145406655 0.1516673380877637 1.0 0.9362432705880748 3 Q8IXJ6 1 +Regulation of calcium mediated signaling 0.5972375867305632 1.4329681141288677 0.1518669498493476 1.0 0.9362432705880748 9 P00813,P0DP25 2 +Regulation of neuron projection development 0.3732823118452438 1.4328537186823016 0.151899645860134 1.0 0.9362432705880748 80 P07196,Q96G23,P31749,Q9UQB8,Q9Y4G8,Q9NR77,Q9NZQ3,Q08209,P08670,Q9NQC3,Q05086,Q8WWV3,Q32P28,Q13439,Q86X55,Q7L576,P10586 17 +Central nervous system neuron differentiation 0.463358653197261 1.432725176233429 0.1519363917007565 1.0 0.9362432705880748 20 Q7Z4L5,Q9UNW9,Q9Y4G8,O14949,Q8NCM8,Q8N3R9 6 +Lymphocyte activation 0.3460775522666754 1.432587265306919 0.1519758231909835 1.0 0.9362432705880748 104 P12956,P62942,Q08209,P46379,Q5RKV6,P30825,Q9UQ84,P24390,Q9NUQ9,P0CG08,P31749,O96005,Q8WXW3,P00813,Q92990,Q9HCL2,P14174,P55327,P78318,P35579,P09429 21 +Lipid import into cell 0.6280350645693921 1.430568203685999 0.1525540056888075 1.0 0.9362432705880748 7 P31751 1 +Membrane protein ectodomain proteolysis 0.5619493654883851 1.4282472588006674 0.1532207024491296 1.0 0.9362432705880748 11 P35579,Q9NZ08,Q8TCT9 3 +Positive regulation of viral life cycle 0.6121901816543002 1.4275208542936748 0.1534298184785383 1.0 0.9362432705880748 8 Q06787,Q9H9H4,P07237,P19474 4 +Vasculogenesis 0.5961325773440405 1.4272332389761886 0.1535126766126986 1.0 0.9362432705880748 9 O95470,Q96PU8,Q9Y4G8 3 +Steroid hormone biosynthetic process 0.6269062169485214 1.4251308417837574 0.1541193828554095 1.0 0.9362432705880748 7 Q14849,P30536 2 +Positive regulation of cilium assembly 0.5954524287635478 1.4237024170137291 0.1545326337594981 1.0 0.9362432705880748 9 Q66GS9,P42858,Q96C92,Q9P2S5 4 +Response to muramyl dipeptide 0.6813562049170624 1.4200006771213247 0.1556074839240344 1.0 0.9362432705880748 5 Q96RT1,P08670,Q92974 3 +Endoplasmic reticulum to golgi vesicle mediated transport 0.4148162214386698 1.418806004429204 0.1559555816683608 1.0 0.9362432705880748 67 Q9BVK6,Q9Y282,P49257,Q13190,Q9HD26,P24390,O95249,Q5JRA6,Q8NHH9,Q9NR31,Q08379,Q15363,O95070,O43731,Q15437,Q9P2W9,P49755,O60763,O15027,Q96PC5 20 +Collagen fibril organization 0.6252607046605916 1.417202061733171 0.1564238591824063 1.0 0.9362432705880748 7 Q96AY3,O75718,Q92791 3 +Mammary gland epithelial cell proliferation 0.6251792728738392 1.416809604107908 0.1565386009906846 1.0 0.9362432705880748 7 Q9Y297,Q9NQC3,Q15648 3 +Positive regulation of pattern recognition receptor signaling pathway 0.577268850612895 1.4160155939845118 0.1567709388400089 1.0 0.9362432705880748 10 Q9Y4E8,P09429,Q9NQC3 3 +Negative regulation of production of mirnas involved in gene silencing by mirna 0.8155298553781245 1.414269710564789 0.1572827267883236 1.0 0.9362432705880748 3 O75844 1 +Regulation of protein neddylation 0.6797597262032791 1.412985545754885 0.157659974115665 1.0 0.9362432705880748 5 Q92564 1 +Positive regulation of glycogen metabolic process 0.9508730393607586 1.4126083353837664 0.1577709168433121 1.0 0.9362432705880748 2 P31751 1 +Negative regulation of fatty acid transport 0.9508730393607586 1.4126083353837664 0.1577709168433121 1.0 0.9362432705880748 2 P31751 1 +Mammary gland epithelial cell differentiation 0.9508730393607586 1.4126083353837664 0.1577709168433121 1.0 0.9362432705880748 2 P31751 1 +Insulin receptor signaling pathway 0.4648322930246759 1.4123052944500958 0.157860088159027 1.0 0.9362432705880748 33 Q9Y5X3,P31751,P31749,O15294,Q9H1E3,Q6ZWJ1,P49841,Q9UQB8,Q8TBX8,P25054,P49815,Q86YS7,Q92572,O14654,P62993,P43490,P11802 17 +Methionine metabolic process 0.7268911893215626 1.4120583334141676 0.1579327859128096 1.0 0.9362432705880748 4 Q13126,Q9BV57 2 +Methionine biosynthetic process 0.7268911893215626 1.4120583334141676 0.1579327859128096 1.0 0.9362432705880748 4 Q13126,Q9BV57 2 +Cellular response to nutrient 0.6234706896208858 1.4085733379731262 0.1589613672452428 1.0 0.9362432705880748 7 P09601,Q15648 2 +Inner ear morphogenesis 0.6233597532516928 1.4080384482349104 0.1591196853837857 1.0 0.9362432705880748 7 Q8IZL8 1 +Negative regulation of response to cytokine stimulus 0.6231803009383008 1.40717317241936 0.1593760446738525 1.0 0.9362432705880748 7 Q7Z739,Q14166,Q9UIV1,Q9Y3Z3 4 +Regulation of t cell differentiation in thymus 0.9488014205386216 1.4044957508749591 0.1601712760983522 1.0 0.9369742515544172 2 P00813 1 +Wnt protein secretion 0.8129070455890945 1.4039601038355158 0.1603307301907197 1.0 0.9369742515544172 3 Q9H3S7,Q5T9L3 2 +Selective autophagy 0.463302001896566 1.3990014188499411 0.1618125575889326 1.0 0.9369742515544172 29 O43464,P53365,Q13501,P49815,P42858,Q9UMX0,P21796,Q96HY6,Q9Y4P1 9 +Regulation of establishment of protein localization to mitochondrion 0.5063735076611665 1.398779377998752 0.1618791521464486 1.0 0.9369742515544172 16 O43464,P55786,P49257,O14737 4 +Response to oxidative stress 0.3411029114836613 1.398253360242497 0.1620369981048031 1.0 0.9369742515544172 100 Q99720,P09601,P31749,Q8IXJ6,Q8N0U8,P30519,Q05086,Q9NR28,P28074,P16615,O43169,Q15392,P09493,Q9UMX0,O95831 15 +Negative regulation of cellular catabolic process 0.3368680844253839 1.3942823236970772 0.1632323665774753 1.0 0.9369742515544172 94 Q9H2J4,P46379,Q9H074,P42704,Q96KB5,Q07820,P30536,P31749,Q08379,O15294,P67809,Q8N163,P09601,Q04323,P98175,Q14011,O60506,Q9H2U1,Q99729,Q08J23,P49815,O15372,Q96JB5,Q96HY6,Q92804,Q8IXJ6,P35637,Q9NNW5,P49069,Q96QK1 30 +Dicarboxylic acid transport 0.4836306992125325 1.392212600022826 0.1638580283696418 1.0 0.9369742515544172 18 Q9H2D1 1 +Peptidyl glutamic acid modification 0.6750000665884713 1.3920593402758976 0.1639044293943337 1.0 0.9369742515544172 5 Q8N0U8 1 +Cerebellar purkinje cell layer morphogenesis 0.6749130486732206 1.391676603552055 0.1640203502610873 1.0 0.9369742515544172 5 Q7Z4L5,O15020 2 +Regulation of protein localization to endosome 0.7218946635977805 1.3912552734786827 0.164148031453664 1.0 0.9369742515544172 4 P15311,O75116 2 +Positive regulation of protein localization to early endosome 0.7218946635977805 1.3912552734786827 0.164148031453664 1.0 0.9369742515544172 4 P15311,O75116 2 +Positive regulation of proteolysis 0.3379695689810449 1.390990973477945 0.1642281639686917 1.0 0.9369742515544172 96 Q9Y4X5,P46379,Q9Y5A7,O14737,Q14997,Q9Y297,P61289,P10909,P31749,Q96A26,Q06323,O15294,O43464,Q9NR28,Q9UL46,O75116,O60826,Q9UMX0,O95831,Q96JB5,Q96HY6,Q9UBS8,Q8IXJ6,P35579,P09429,O75150,Q9BXK5 27 +Multicellular organismal response to stress 0.6044107304862928 1.3886154109452056 0.1649497286006391 1.0 0.9369742515544172 8 P30536,P31749 2 +Labyrinthine layer blood vessel development 0.6331096650790857 1.38695063879186 0.1654568150194844 1.0 0.9369742515544172 6 P31749 1 +Mitochondrial electron transport cytochrome c to oxygen 0.632903370432104 1.3859891520533305 0.1657502159595889 1.0 0.9369742515544172 6 P00403 1 +Reverse cholesterol transport 0.9440662918023084 1.385958015539666 0.1657597239112287 1.0 0.9369742515544172 2 P10909 1 +Microtubule anchoring at centrosome 0.6733957242152743 1.3850019927655517 0.1660518580267298 1.0 0.9369742515544172 5 Q14203,Q15154 2 +Regulation of fat cell differentiation 0.4934996785351554 1.382041288350627 0.1669590239895275 1.0 0.9369742515544172 17 Q8IXJ6,Q86X55,Q8N4Q0,P31749 4 +Liver morphogenesis 0.806664183388718 1.379417005344137 0.1677662191037767 1.0 0.9370621082476722 3 Q15418 1 +Positive regulation of leukocyte cell cell adhesion 0.4601052023731667 1.37689925888511 0.1685433963841849 1.0 0.9370621082476722 27 Q9NUQ9,Q9HCL2,P00813,P31749 4 +Negative regulation of dendrite morphogenesis 0.8050984115627806 1.3732607426176473 0.1696713021563218 1.0 0.9370621082476722 3 Q9Y4G8 1 +Protein containing complex remodeling 0.9405149452500738 1.3720602486205178 0.1700446829142337 1.0 0.9370621082476722 2 Q8WTV0 1 +Pituitary gland development 0.804785765079689 1.3720314679070422 0.1700536419196718 1.0 0.9370621082476722 3 O94788 1 +T cell differentiation 0.4584246068875091 1.3696127774978073 0.1708078088489135 1.0 0.9370621082476722 25 P0CG08,O96005,P09429,P00813,P24390 5 +Animal organ maturation 0.8037594618858824 1.3679961762064978 0.1713132730163908 1.0 0.9370621082476722 3 O94788 1 +Positive regulation of cell cycle checkpoint 0.6688388625592366 1.3649473031038335 0.1722696133071659 1.0 0.9370621082476722 5 P12270,Q13257,Q8N163,Q5JVF3 4 +Response to ether 0.7154886615677232 1.3645670639819871 0.1723891624938058 1.0 0.9370621082476722 4 Q9H4A6,P11802 2 +Inner cell mass cell proliferation 0.7152435602286348 1.3635456106529684 0.1727106200650179 1.0 0.9370621082476722 4 P61201,Q9BRT9 2 +Retrograde transport endosome to golgi 0.4562943963534366 1.360854456288953 0.1735596886379378 1.0 0.9370621082476722 39 O95249,Q9Y5X3,Q14203,Q4J6C6,O43752,Q9BVK6,Q9UID3,O60271,Q8IUD2,Q9UNH7,P49257,Q13190,Q96QK1,O15260 14 +Divalent inorganic cation homeostasis 0.4348550547900578 1.3600063464259462 0.1738279155790072 1.0 0.9370621082476722 56 P62942,Q9Y4W6,Q6P4Q7,Q9HC07,P78417,Q96A33,P0DP25,Q8IYU8,P16615,P42858,Q9HD20,Q9NWR8,Q8NEW0,Q9BPX6 14 +Nucleoside triphosphate metabolic process 0.4443594236762835 1.3550740905313408 0.175393952615821 1.0 0.9370621082476722 50 P00846,Q8IWA4,O00178,Q9Y3Z3,O75964,P00403,O60313,Q13232,Q9H773,P00813 10 +Organelle transport along microtubule 0.4579709886052182 1.3547646915211056 0.1754925393895323 1.0 0.9370621082476722 31 O75381,P07196,Q8WXH0,Q9Y2T2,O60313,Q8TD16,P42858,P42704 8 +Ceramide biosynthetic process 0.5240726365105144 1.3508803892357204 0.1767337511543292 1.0 0.9370621082476722 13 Q16739 1 +Positive regulation of transporter activity 0.4558323888862773 1.3491632972906265 0.1772845208073097 1.0 0.9370621082476722 25 P35609,P78417,P0DP25,Q03164,O43707,P42858 6 +Regulation of i kappab phosphorylation 0.9345960343296836 1.3489096809129897 0.1773659783329129 1.0 0.9370621082476722 2 P31749 1 +Positive regulation of i kappab phosphorylation 0.9345960343296836 1.3489096809129897 0.1773659783329129 1.0 0.9370621082476722 2 P31749 1 +Regulation of phosphoprotein phosphatase activity 0.498601591345134 1.347163214381805 0.1779276725026548 1.0 0.9370621082476722 16 P62942,O75116,P0DP25,P42858 4 +Cellular response to arsenic containing substance 0.5806997460884169 1.3469562285684626 0.1779943304286051 1.0 0.9370621082476722 9 Q96QD8,P78417,P09601 3 +Regulation of appetite 0.9340041432376452 1.3465955668828888 0.1781105227024741 1.0 0.9370621082476722 2 P80303 1 +Negative regulation of response to food 0.9340041432376452 1.3465955668828888 0.1781105227024741 1.0 0.9370621082476722 2 P80303 1 +Regulation of response to food 0.9340041432376452 1.3465955668828888 0.1781105227024741 1.0 0.9370621082476722 2 P80303 1 +Segmentation 0.5076453816066108 1.3459458659419952 0.178319975500619 1.0 0.9370621082476722 15 Q15363,Q8N2A8,O94788,O14641 4 +Digestive system development 0.5226589107177796 1.3422880719370884 0.1795026094586875 1.0 0.9370621082476722 13 P00813,Q5T9L3 2 +Protein localization to cell periphery 0.3385470983918833 1.3420812044027317 0.1795696674310958 1.0 0.9370621082476722 102 Q9H4A5,P31751,Q9Y4G8,Q13439,Q9BZG1,Q5VZ89,Q9HD26,P31749,P33176,Q13277,Q9H4A6,Q15363,P15311,Q14BN4,O00264,P98194,Q01082,Q13501,Q9UJY4,O75116,Q15276,P35609,Q96A65,Q4J6C6,Q4V328,O15027,Q8N3R9 27 +Heparan sulfate proteoglycan metabolic process 0.6636222604852051 1.3419733909594052 0.1796046235095021 1.0 0.9370621082476722 5 Q7LGA3 1 +Cilium organization 0.4075017977444644 1.339553977078982 0.1803903948269325 1.0 0.9370621082476722 67 Q9UBB4,Q9BV73,Q15154,P50570,P42858,Q8WXH0,Q9H3S7,Q15019,O95721,Q8WXW3,Q9Y3P9,A6NIH7,Q9H223,Q14203,Q66GS9,Q9P2S5,O43805,Q96C92,Q8NCM8,Q7Z4L5,Q96A65,Q15555,A0AVF1,Q9Y5K8,Q14141 25 +Negative regulation of smooth muscle cell proliferation 0.6091578896782365 1.3394533442323933 0.1804231333457597 1.0 0.9370621082476722 7 P09601 1 +Regulation of cilium assembly 0.4511039202103938 1.338343191725074 0.1807845881752934 1.0 0.9370621082476722 20 Q66GS9,Q9P2S5,Q96C92,P42858,Q9Y3P9 5 +Establishment of protein localization to organelle 0.3903285281653005 1.337804389126703 0.1809602107428258 1.0 0.9370621082476722 193 P40855,O60830,O60220,Q08209,Q9Y5J7,Q9Y2T2,P46379,Q96P70,Q8N8Q8,Q7L5D6,Q15388,Q9NS69,O43681,Q99595,Q9Y5J9,P49257,P50542,O00170,Q10713,O14737,Q9H9H4,O75381,O14925,P52789,Q8N4H5,P10909,P30536,O75312,O00410,P31749,Q9UHB9,Q9H3S7,P55786,Q8TB36,Q53H12,Q99567,Q15005,P33908,O95429,Q8N1F7,Q15648,O43464,Q13501,Q9Y5M8,P12270,P78371,Q15629,P49815,O95831,Q92973,O14964,Q9GZY8,P0DP25,P06493,Q5JRX3,P49368,Q8TEX9,Q9BRG1 58 +Lymphocyte apoptotic process 0.4635336628583281 1.3344749262556186 0.1820482588989977 1.0 0.9370621082476722 19 P00813,Q9HCL2,P24390 3 +Regulation of amyloid precursor protein catabolic process 0.4966282284087437 1.3340365264502967 0.1821918860587534 1.0 0.9370621082476722 16 O75298,P62942,P10909,Q96P70,O95197,Q9NQC3,P49755 7 +Humoral immune response mediated by circulating immunoglobulin 0.7945529899348743 1.33179729421571 0.1829268073438512 1.0 0.9370621082476722 3 Q9UQ84,P10909 2 +Smooth muscle cell proliferation 0.4628943171265695 1.3297353622120098 0.1836054793536177 1.0 0.9370621082476722 19 P09601,P09493,P31749 3 +Protein localization to golgi apparatus 0.5612611696569852 1.3292695965484929 0.1837590411199483 1.0 0.9370621082476722 10 Q8TD16,Q9H4A6,P49755,Q8IWJ2 4 +Mitochondrion endoplasmic reticulum membrane tethering 0.9292690145013318 1.3280895152743029 0.1841485367329673 1.0 0.9370621082476722 2 O43865 1 +Diterpenoid biosynthetic process 0.9289730689553124 1.3269333128097436 0.1845307434433314 1.0 0.9370621082476722 2 O94788 1 +Cellular response to chemical stress 0.3495990878646156 1.3258027023091732 0.1849050576890683 1.0 0.9370621082476722 84 Q99720,P09601,P30536,Q8IXJ6,P31749,Q8N0U8,Q9NR28,P09493,Q9UMX0,O95831,Q9BPX6 11 +Calcium ion import into sarcoplasmic reticulum 0.9286771234092924 1.3257771627771069 0.1849135196141909 1.0 0.9370621082476722 2 P16615 1 +Protein trimerization 0.7060193040009743 1.3250894687078274 0.185141478661857 1.0 0.9370621082476722 4 Q99720 1 +Negative regulation of fat cell differentiation 0.6057925363753118 1.3231724512545315 0.1857780351808604 1.0 0.9370621082476722 7 Q8N4Q0 1 +Positive regulation of protein targeting to membrane 0.5433439718239956 1.3230907423249283 0.1858052030048012 1.0 0.9370621082476722 11 P31751 1 +Positive regulation of ubiquitin dependent protein catabolic process 0.4538292251507124 1.321028296274128 0.1864919294698139 1.0 0.9370621082476722 31 Q9UBS8,P10909,P31749,Q9Y4X5,Q8IXJ6,Q96JB5,Q9Y5A7,O60826,Q9UMX0,Q9BW61,Q96HY6 11 +N terminal protein amino acid acetylation 0.7048131052833224 1.3200590812771231 0.1868152930488618 1.0 0.9370621082476722 4 Q86UY6 1 +Mitochondrial respiratory chain complex assembly 0.4475754917089176 1.3191144310814986 0.1871308593376426 1.0 0.9370621082476722 44 Q7L592,Q8N8Q8,P03886,Q9H061,Q86Y39,Q69YU5,P56556,O43676,Q96CU9,Q9NVA1,O96000,O95831,Q9BRT2,O75880,Q6DKK2,Q9Y2R0,Q9BSH4,O43674,Q9BSK2 19 +Lactation 0.5186747454089963 1.318054061393816 0.1874855511800748 1.0 0.9370621082476722 13 P52789,Q13505,P61201,P00403,P16220 5 +Definitive hemopoiesis 0.7907469701940801 1.3168339168184942 0.1878943012919212 1.0 0.9370621082476722 3 Q96JB5 1 +Regulation of lysosomal lumen ph 0.6573787627474845 1.3144581390953525 0.1886920763766839 1.0 0.9370621082476722 5 Q8N511 1 +Regulation of cation channel activity 0.4495546372250937 1.3140073777566073 0.188843721457961 1.0 0.9370621082476722 22 P35609,P78417,P0DP25,P42858,Q9UMX0 5 +Positive regulation of protein secretion 0.4516816982169931 1.3097408775507124 0.1902835099151456 1.0 0.9370621082476722 27 Q9H3S7,Q9H4A5,O95563,O00429,P35580,Q9H4A6,P15311,P49755,Q5T9L3 9 +Modification of synaptic structure 0.5729998929236911 1.3067920452014403 0.1912833475447048 1.0 0.9370621082476722 9 Q9UQB8,Q4V328,Q7L576 3 +Mitophagy 0.4922618571175878 1.3049643727925884 0.1919049795744936 1.0 0.9370621082476722 16 O43464,P53365,Q13501,P49815,P21796,Q9Y4P1 6 +Establishment of protein localization to plasma membrane 0.4513161329066836 1.3024811673437544 0.1927519517307947 1.0 0.9370621082476722 29 Q9H4A5,Q4J6C6,Q4V328,Q13439,Q9BZG1,Q9H4A6,Q9UJY4,O15027,P98194,Q01082,Q9HD26 11 +Erad pathway 0.4473027301077967 1.3013536454573669 0.193137432651808 1.0 0.9370621082476722 42 O95155,Q8TCT9,P46379,Q96A33,P33908,Q9UBV2,Q9UMX0 7 +Negative regulation of mitochondrion organization 0.4816282301547473 1.3003637260898806 0.1934763361864377 1.0 0.9370621082476722 17 O60313,P30536,P10909,P31749 4 +Cerebral cortex radially oriented cell migration 0.5867975266151879 1.300272174262099 0.1935077014334707 1.0 0.9370621082476722 8 P07942,Q8WXH0,Q9NQC3,O94901 4 +Telencephalon glial cell migration 0.5867975266151879 1.300272174262099 0.1935077014334707 1.0 0.9370621082476722 8 P07942,Q8WXH0,Q9NQC3,O94901 4 +Positive regulation of calcium ion transmembrane transport 0.515539728709322 1.298966304618468 0.1939554931043732 1.0 0.9370621082476722 13 P78417,P0DP25 2 +Embryonic placenta morphogenesis 0.6995562494331525 1.2981324221046395 0.1942418348363026 1.0 0.9370621082476722 4 Q15363,P62993 2 +Negative regulation of receptor signaling pathway via jak stat 0.699048130425267 1.296012805841746 0.1949710730419496 1.0 0.9370621082476722 4 Q8WXW3,O14964 2 +Negative regulation of receptor signaling pathway via stat 0.699048130425267 1.296012805841746 0.1949710730419496 1.0 0.9370621082476722 4 Q8WXW3,O14964 2 +Cerebral cortex cell migration 0.5210914623325423 1.2952565410281185 0.1952317457576047 1.0 0.9370621082476722 12 O94901,Q9NQC3,P50542,P07942,Q8WXH0 5 +Regulation of intracellular protein transport 0.3763781586753657 1.2947836785436688 0.1953948638981604 1.0 0.9370621082476722 76 P31751,Q9Y282,Q15154,P49257,O14737,Q9NR31,Q13438,O75312,O00410,P55786,Q9C0E2,O95429,Q9H6U6,O43464,P49841,P12270,Q4V328,Q9GZY8,P06493,P50402,Q92544 21 +Purine deoxyribonucleotide catabolic process 0.7847270962172768 1.293171265414175 0.1959518314847805 1.0 0.9370621082476722 3 P00813 1 +Cellular hormone metabolic process 0.4578191788589894 1.2920795261724185 0.1963296053634091 1.0 0.9370621082476722 19 P30536,Q14849,O94788,O60678,O95470 5 +Positive regulation of early endosome to late endosome transport 0.6123982112442858 1.29024114326443 0.1969669450963702 1.0 0.9370621082476722 6 P35241,P15311,Q9H3S7 3 +Positive regulation of cytoplasmic transport 0.6123982112442858 1.29024114326443 0.1969669450963702 1.0 0.9370621082476722 6 P35241,P15311,Q9H3S7 3 +Positive regulation of protein neddylation 0.7832355418367575 1.287309501660783 0.1979864330638243 1.0 0.9370621082476722 3 Q92564 1 +Regulation of blood circulation 0.4489657880376389 1.2854843617099234 0.1986230780341671 1.0 0.9370621082476722 28 P78417,P0DP25,P16615,P09493,P00813 5 +Negative regulation of vascular associated smooth muscle cell proliferation 0.61113123573233 1.2843153681333943 0.1990316317167582 1.0 0.9370621082476722 6 P09601 1 +Striated muscle adaptation 0.6504063976941312 1.2837113906193396 0.1992429573959677 1.0 0.9370621082476722 5 P16615,Q13555,Q08209 3 +Cellular response to osmotic stress 0.5121851213049983 1.2785246092457097 0.2010645133340149 1.0 0.9370621082476722 13 P30536 1 +Cellular response to potassium ion 0.6947524058948386 1.2780922351664914 0.2012169064663498 1.0 0.9370621082476722 4 P55011,Q14168 2 +Response to potassium ion 0.6947524058948386 1.2780922351664914 0.2012169064663498 1.0 0.9370621082476722 4 P55011,Q14168 2 +Embryo implantation 0.5517896503135289 1.2777824022553803 0.2013261609540373 1.0 0.9370621082476722 10 Q7Z7E8,P35613,Q02790,Q07021,Q8IZL8 5 +Positive regulation of b cell proliferation 0.6946656736672111 1.2777303998153178 0.2013445024967193 1.0 0.9370621082476722 4 P00813 1 +Amyloid beta clearance 0.5119348254314633 1.2769987370853122 0.2016026931291583 1.0 0.9370621082476722 13 Q16850,P10909 2 +Sterol biosynthetic process 0.4455134070369221 1.276968819835872 0.201613255524462 1.0 0.9370621082476722 23 P48449,Q16850,Q15125,Q15800,Q15392,P53396,P16435,Q14739 8 +Skeletal muscle contraction 0.6938929000020526 1.2745064786497724 0.2024839780960952 1.0 0.9370621082476722 4 P78417 1 +Negative regulation of receptor binding 0.915359573838414 1.2738112255423322 0.2027303258650041 1.0 0.9370621082476722 2 P16615 1 +Multicellular organismal movement 0.5662162802766514 1.2713570937687722 0.2036016394165747 1.0 0.9370621082476722 9 P78417,Q7Z406 2 +Organic acid transmembrane transport 0.446844603141296 1.26907959688108 0.2044126764525544 1.0 0.9370621082476722 36 O43772,Q9H2D1,P31749,P31751,P30825,Q9UBX3 6 +Organic hydroxy compound catabolic process 0.5033292660272503 1.267049913684693 0.2051374430285617 1.0 0.9370621082476722 14 P30837,P16930,Q9NX62,P21964,P43304,Q8WTV0 6 +Nuclear pore complex assembly 0.5651036948227863 1.265541497516266 0.2056772824792501 1.0 0.9370621082476722 9 Q9BTX1,Q9NQC3,Q8N1F7 3 +Maternal process involved in female pregnancy 0.5157247768450328 1.2633973636870124 0.2064464111150308 1.0 0.9370621082476722 12 Q8IZL8,Q9BQE5 2 +Acute inflammatory response 0.6457500525599486 1.2631694578927593 0.2065282865102564 1.0 0.9370621082476722 5 Q9BQE5 1 +Response to nerve growth factor 0.5148767198431988 1.258359336540227 0.2082618309056174 1.0 0.9370621082476722 12 Q05086,P31749 2 +Oxidative phosphorylation 0.4049395887430823 1.2561989102693822 0.209043861757298 1.0 0.9370621082476722 65 P00846,O75964,Q9UDW1,P22695,P00403,O43674,P56556,P03886,O75208,P06493,O14949,P06576,O96000,P24539,P13073,O43676,P14406,Q9BRT2 18 +Positive regulation of fat cell differentiation 0.5632992426209094 1.2561073518093182 0.2090770510056721 1.0 0.9370621082476722 9 Q86X55,P31749 2 +Anterograde axonal transport 0.4849258289336011 1.2560437647645608 0.2091001030739205 1.0 0.9370621082476722 16 O60333,Q9Y2T2,P07196,Q14168 4 +Histone h3 deacetylation 0.6049146282541514 1.2552277866089068 0.2093960812278577 1.0 0.9370621082476722 6 Q8IXJ6 1 +Regulation of extrinsic apoptotic signaling pathway in absence of ligand 0.5310838023572334 1.2535157759416498 0.2100180614046447 1.0 0.9370621082476722 11 O43464,P30154,O95677,P31749 4 +Cell migration involved in sprouting angiogenesis 0.5626367591628473 1.2526430939680728 0.2103356242790435 1.0 0.9370621082476722 9 P09601 1 +Cardiac muscle tissue morphogenesis 0.5911694206489893 1.2523308301133982 0.2104493392852893 1.0 0.9370621082476722 7 P62942,P09493 2 +Cardiac ventricle morphogenesis 0.5911694206489893 1.2523308301133982 0.2104493392852893 1.0 0.9370621082476722 7 P62942,P09493 2 +Muscle organ morphogenesis 0.5911694206489893 1.2523308301133982 0.2104493392852893 1.0 0.9370621082476722 7 P62942,P09493 2 +Ventricular cardiac muscle tissue morphogenesis 0.5911694206489893 1.2523308301133982 0.2104493392852893 1.0 0.9370621082476722 7 P62942,P09493 2 +Regulation of dna templated transcription in response to stress 0.5076531020588868 1.2508828672561882 0.2109772154747369 1.0 0.9370621082476722 13 Q8IXJ6,P09601 2 +Positive regulation of leukocyte proliferation 0.46369623283106 1.2499289250617924 0.2113255120319865 1.0 0.9374924770306046 18 P14174,P00813,P30825,Q9HCL2 4 +Release of sequestered calcium ion into cytosol by endoplasmic reticulum 0.6036447093910742 1.2492837048134149 0.2115613258094018 1.0 0.9374924770306046 6 P78417 1 +Glycerol 3 phosphate metabolic process 0.9088487718259852 1.2484559578541812 0.2118641275404691 1.0 0.9374924770306046 2 Q9HCL2 1 +Regulation of protein complex stability 0.6423023842756619 1.2479567829703762 0.2120468842083795 1.0 0.9374924770306046 5 Q13501,Q9BQ95,Q969V3 3 +Tetrapyrrole metabolic process 0.4402561931684606 1.2476830743703118 0.212147142061547 1.0 0.9374924770306046 21 P30519,P30536 2 +Lung alveolus development 0.6029623698252354 1.246089637720272 0.2127314886565803 1.0 0.9374924770306046 6 O60476,P00813 2 +Calcium ion transmembrane transport 0.4392960055794431 1.2457266109357714 0.2128647805940557 1.0 0.9374924770306046 44 P62942,Q9HC07,P78417,P0DP25,Q8IYU8,P16615,P42858,Q9UMX0,Q9NWR8,P21796,Q9BPX6 11 +Lipid homeostasis 0.4435748523367253 1.24493953504815 0.2131539770109394 1.0 0.9374924770306046 27 Q9HCL2,Q86YV9,Q15067,Q9NQC3,O15254,Q9Y6C9,O15260,Q8WTV0 8 +Heparan sulfate proteoglycan biosynthetic process 0.6866684104854366 1.2443671269643222 0.2133644757931605 1.0 0.9374924770306046 4 Q7LGA3 1 +Gland development 0.3688341019082745 1.2435797000151705 0.2136542912423156 1.0 0.9374924770306046 77 P09601,P30536,P31751,Q13505,P31749,O94788,P00403,Q9NQC3,Q05086,O75844,P16220,Q96JB5,P00813,Q5T9L3 14 +Dna methylation involved in gamete generation 0.7720544701006516 1.2433900217955844 0.2137241454556637 1.0 0.9374924770306046 3 Q8N2A8,Q9Y2W6 2 +Type b pancreatic cell development 0.6412386091308178 1.243262569765026 0.2137710924211988 1.0 0.9374924770306046 5 P49841,P31749 2 +Endoplasmic reticulum tubular network organization 0.528705182268838 1.2399973273515208 0.2149763826954973 1.0 0.9374924770306046 11 Q8NHH9,Q9H6H4,Q9H2M9,O95197,Q9NQC3,Q6NUK4,Q15042 7 +Cartilage development involved in endochondral bone morphogenesis 0.6855120761784934 1.239543430963186 0.2151443152282381 1.0 0.9374924770306046 4 O75844 1 +Negative regulation of signal transduction in absence of ligand 0.5884826722665857 1.239301233596821 0.2152339620499326 1.0 0.9374924770306046 7 O95677,P31749 2 +Cellular transition metal ion homeostasis 0.4378541803313081 1.2358622100816803 0.2165097860180953 1.0 0.9407713187334596 20 Q9Y487,P09601 2 +Regulation of cellular protein catabolic process 0.3266415000203476 1.2350435183971271 0.2168143083218519 1.0 0.940825200848358 95 Q9Y4X5,Q9H2J4,P46379,Q9Y5A7,Q9Y297,Q9BW61,P61289,Q96KB5,P10909,P31749,P15311,Q06323,O15294,Q8N163,Q92990,Q04323,P49841,Q05086,Q9UL46,O60826,Q9UMX0,O15372,Q96JB5,Q96HY6,Q9UBS8,Q8IXJ6,P49069,Q96QK1,O75150 29 +Lipopolysaccharide mediated signaling pathway 0.559164002436957 1.23447830602878 0.2170247256704711 1.0 0.940825200848358 9 P14174,Q8WTV0,P31749 3 +Regulation of type b pancreatic cell development 0.7696862048549409 1.2340936899264898 0.2171679945853744 1.0 0.940825200848358 3 P49841,P31749 2 +Metal ion export 0.5586884196490798 1.231990079311191 0.2179527900165951 1.0 0.9412060499437664 9 Q12959,P05023,O95202,P05026,P0DP25,Q4KMQ2 6 +Axis specification 0.5586778278527144 1.231934661939888 0.2179734921366292 1.0 0.9412060499437664 9 Q8N2A8,Q15363,Q5T9L3 3 +Dorsal ventral pattern formation 0.5997158615532525 1.2308903819612058 0.2183638653279911 1.0 0.9412060499437664 6 Q7Z4L5 1 +Regulation of response to endoplasmic reticulum stress 0.4407048104241428 1.2294892128870871 0.2188884398189694 1.0 0.9412060499437664 25 Q9UMX0,P46379,Q96HY6,P10909 4 +Inorganic anion transmembrane transport 0.557643623821678 1.2265232740022685 0.2200018224590465 1.0 0.9431099319331046 9 P55011,Q9UBX3,Q9UHG3 3 +Negative regulation of g protein coupled receptor signaling pathway 0.5984755334424482 1.2250826714342953 0.2205440734525425 1.0 0.944025765186434 6 P00813 1 +Positive regulation of small molecule metabolic process 0.48010299927847 1.2238385296437364 0.2210131462827949 1.0 0.9451348488012146 16 P31749,P00403,P31751 3 +Post translational protein modification 0.5566912306626647 1.2215394037171252 0.2218818558891613 1.0 0.945985455942629 9 O60725,Q32P28 2 +Regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion 0.6355400866665208 1.2181147438046198 0.2231803718087703 1.0 0.945985455942629 5 P78417 1 +Leukocyte apoptotic process 0.4386240376842506 1.2176730970347671 0.2233482244149147 1.0 0.945985455942629 24 P31749,P00813,Q9HCL2,P24390 4 +Mitotic nuclear membrane organization 0.583933978370665 1.2172352695401325 0.2235147145887936 1.0 0.945985455942629 7 Q86XL3 1 +Positive regulation of protein export from nucleus 0.5406406011922559 1.2170616899174826 0.2235807452931517 1.0 0.945985455942629 10 Q14012,P49841,P12270,Q9C0E2,P50402,Q9Y3B8 6 +Positive regulation of canonical wnt signaling pathway 0.4590716193901202 1.2168140075373302 0.2236749892762888 1.0 0.945985455942629 18 Q7Z4L5,Q5T9L3 2 +Glycolipid biosynthetic process 0.5243235189378673 1.2150810879535083 0.2243351658753498 1.0 0.945985455942629 11 Q16739 1 +Amyloid beta formation 0.5074645060123243 1.2142896901089686 0.2246371212281221 1.0 0.945985455942629 12 O75298,P10909,O95197,Q9NQC3,P49755 5 +Cellular response to estrogen stimulus 0.6346376692061022 1.214132276969575 0.2246972163277831 1.0 0.945985455942629 5 Q8IZL8 1 +Calcium ion export 0.6791423358103876 1.212975715545264 0.2251391052818152 1.0 0.9465294827019828 4 P0DP25 1 +Synaptic vesicle endosomal processing 0.6338365126654173 1.210596709507972 0.2260500059847361 1.0 0.94854888225595 5 O43752,Q4V328 2 +Dendrite extension 0.6335652328538901 1.2093995374112658 0.2265093862879266 1.0 0.9498734352645348 5 Q7L576 1 +Regulation of pattern recognition receptor signaling pathway 0.4367644406849617 1.208295287158487 0.2269337006146079 1.0 0.9499792925386747 23 Q96RT1,Q9NPR9,Q9Y4E8,O43657,Q9NQC3,Q9NUD5,P09429,Q9UMX0 8 +Feeding behavior 0.5683586011637822 1.207511169248559 0.2272353462570742 1.0 0.9499792925386747 8 Q7Z4L5 1 +Blastocyst formation 0.5004682234403202 1.207009585315814 0.2274284525542136 1.0 0.9499792925386747 13 Q13895,P00813,Q9NQC3 3 +Modification of postsynaptic actin cytoskeleton 0.6328798544182109 1.2063749470355014 0.2276729514375248 1.0 0.9499792925386747 5 Q9UQB8 1 +Collateral sprouting 0.677228309150127 1.2049942440132335 0.2282055239682843 1.0 0.9499792925386747 4 P53990,Q15375,Q8N0X7 3 +Activated t cell proliferation 0.5941452021451983 1.2048035810735735 0.2282791372235766 1.0 0.9499792925386747 6 Q9BY67,P09429,Q9HCL2 3 +Response to amphetamine 0.6323742211316677 1.204143598466657 0.2285340812005367 1.0 0.9499792925386747 5 P0DP25 1 +Regulation of muscle organ development 0.5378524497405547 1.2018620717759223 0.2294169714788498 1.0 0.9499792925386747 10 Q8IXJ6 1 +Regulation of cell development 0.3235770028126025 1.199727106505274 0.2302453420197809 1.0 0.9514160418917847 94 Q9Y4G8,Q08209,Q9NQC3,Q15154,Q13439,P50570,P55209,P30536,P31749,O15031,O43707,Q07021,Q7L576,Q8N0X7,Q96G23,P49841,Q9UQB8,Q9H2U1,O75116,P07196,P35611,Q8IXJ6,P26583,Q15058,O15144 25 +Negative regulation of reproductive process 0.5930210214104853 1.1995384771855184 0.2303186326701993 1.0 0.9514160418917847 6 P00813 1 +Sprouting angiogenesis 0.4764326917232613 1.199310384204049 0.230407278813352 1.0 0.9514160418917847 16 P09601,P57105 2 +Regulation of mitochondrial fission 0.5514278362119228 1.1939877916620194 0.2324827436411947 1.0 0.9566818520025884 9 O00429,Q9NUQ9 2 +Regulation of nervous system development 0.3679099890383025 1.1920696526306227 0.2332339351969532 1.0 0.9566818520025884 76 Q08209,Q9Y4G8,Q9NQC3,Q13439,Q96P11,P55209,P31749,O75312,P30536,O15031,Q7L576,Q8N0X7,Q96G23,Q9UQB8,Q9H2U1,P07196,Q8IXJ6,P26583,Q15058 19 +Muscle cell development 0.436803919211684 1.1876500838315367 0.2349712971907622 1.0 0.9566818520025884 28 Q13045,P35609,Q08209,Q9Y4W6,P06493,P02545,P16615,O75844,O43707,P09493,P12814 11 +Regulation of glucose import 0.5027742480741436 1.1863749827514505 0.2354742468232751 1.0 0.9566818520025884 12 O75298,P52789,P31749,P31751 4 +Positive regulation of activated t cell proliferation 0.757252812314956 1.1853377593398084 0.2358839297965023 1.0 0.9566818520025884 3 P09429,Q9HCL2 2 +Ear morphogenesis 0.489876116218582 1.1825510533943142 0.2369871207334903 1.0 0.9578735411180818 14 Q8IZL8 1 +Positive regulation of ion transport 0.4291498864337165 1.1810857388770246 0.2375686646594166 1.0 0.9578735411180818 47 P35609,P31749,P30536,P33176,O43865,P78417,P0DP25,Q99996,O43707,P42858,P14174 11 +Negative regulation of mononuclear cell migration 0.7561407134338309 1.1809816204173769 0.2376100248011621 1.0 0.9578735411180818 3 P31749 1 +Execution phase of apoptosis 0.4734551225683092 1.179401742214075 0.2382382417221555 1.0 0.958318039891495 16 O43464,P31749,Q8IXJ6,O95831,Q12981,Q96JB5 6 +Regulation of receptor binding 0.6708188397977548 1.1782755450852953 0.2386867738250995 1.0 0.9589549472401718 4 P16615 1 +Vitamin transport 0.5480047293479439 1.1760633152097013 0.2395695759414322 1.0 0.9599595162460972 9 Q9H2D1,Q8WTV0 2 +Negative regulation of amyloid precursor protein catabolic process 0.5172985070555558 1.175102860298301 0.2399535664757985 1.0 0.9599595162460972 11 O75298,O95197,P10909,Q9NQC3 4 +Response to endoplasmic reticulum stress 0.3182254963557349 1.169807792703209 0.242078326961733 1.0 0.9641862806298532 89 O95155,Q7L5D6,P46379,Q96A33,O60313,Q9UBV2,P10909,Q8TCT9,Q13438,Q15363,O95881,P33908,Q9H3N1,Q04323,P49841,P32929,Q9UMX0,Q96JB5,O95831,Q96HY6,P16615,O15027 22 +Positive regulation of mitotic cell cycle spindle assembly checkpoint 0.6686408054486164 1.169199887041681 0.2423231066918121 1.0 0.9641862806298532 4 P12270,Q13257,Q5JVF3 3 +C21 steroid hormone biosynthetic process 0.7520367913975313 1.1649144247097976 0.2440536339982757 1.0 0.9660593159673952 3 P30536 1 +Regulation of ubiquitin dependent protein catabolic process 0.4031409860584957 1.1641099519917826 0.2443794560545453 1.0 0.9660593159673952 62 Q9Y4X5,Q9H2J4,P46379,Q9Y5A7,Q9BW61,Q96KB5,P10909,P31749,O15294,Q8N163,Q92990,Q04323,Q05086,O60826,Q9UMX0,O15372,Q96JB5,Q96HY6,Q9UBS8,Q8IXJ6,P49069 21 +Organelle membrane fusion 0.4345328183226427 1.1622913369288996 0.2451171443432209 1.0 0.9660593159673952 33 O95249,P31751,O43752,O95721,Q13277,Q9BZG1,Q15075,Q13190,Q12981,Q8IWA4 10 +Regulation of calcium ion transmembrane transport 0.4315958661863325 1.1621779446207183 0.2451631915694661 1.0 0.9660593159673952 24 P78417,P0DP25,P42858,Q9UMX0,P21796 5 +Protein localization to endoplasmic reticulum exit site 0.6669162361319675 1.1620153808207727 0.2452292173223251 1.0 0.9660593159673952 4 Q5JRA6,O15027 2 +Appendage morphogenesis 0.4790541192545993 1.1611157782449373 0.245594819005978 1.0 0.9660593159673952 15 Q9NX62,O94788,P42892,Q8NCM8,Q15648 5 +Respiratory chain complex iv assembly 0.5717867805928643 1.158284868920344 0.2467478041060102 1.0 0.9660593159673952 7 O75880,Q9Y2R0,Q8N8Q8 3 +Mitochondrial cytochrome c oxidase assembly 0.5717867805928643 1.158284868920344 0.2467478041060102 1.0 0.9660593159673952 7 O75880,Q9Y2R0,Q8N8Q8 3 +Peptidyl lysine dimethylation 0.5840359270250657 1.1574547229178 0.2470866275023839 1.0 0.9660593159673952 6 Q03164 1 +Regulation of ion transport 0.3200408579493523 1.1574161818945663 0.2471023659001916 1.0 0.9660593159673952 93 P55011,P62942,P42858,Q9HD26,P0CG08,P05023,P30536,P31749,P33176,P78417,Q9UNH7,O43707,Q14BN4,P21796,O43865,Q13555,Q99996,Q9UMX0,P14174,P35609,P0DP25,O75844 22 +Meiotic chromosome segregation 0.429404971930409 1.1565507531360444 0.2474559524685351 1.0 0.9660593159673952 22 P46379,Q92791 2 +Organelle disassembly 0.4240697275341152 1.1552717518847275 0.2479791599180232 1.0 0.9660593159673952 49 O43464,Q9Y6I9,Q5MNZ6,P53365,P52789,Q13501,P30536,O00429,P33176,Q08379,Q13190,P41214,P42858,P49815,P21796,Q96HY6,Q9Y4P1 17 +Positive regulation of multicellular organism growth 0.5710977634883995 1.1549407662633622 0.2481146838640913 1.0 0.9660593159673952 7 P15311,P16220,Q9HCL2 3 +Regulation of jun kinase activity 0.5710553859037402 1.154735090175273 0.2481989252122169 1.0 0.9660593159673952 7 O14641 1 +Regulation of lipid localization 0.4322996965313045 1.1546179222246442 0.2482469241130585 1.0 0.9660593159673952 27 P31749,O15260,P30536,P31751 4 +Transition between fast and slow fiber 0.8845812370523831 1.1543370014260428 0.2483620322856654 1.0 0.9660593159673952 2 P16615 1 +Positive regulation of chromatin organization 0.5290873416280502 1.15405431204641 0.2484779028261781 1.0 0.9660593159673952 10 P12270,Q8NEY8 2 +Cellular response to ether 0.7491630790078021 1.1536716738588324 0.248634801249203 1.0 0.9660593159673952 3 Q9H4A6 1 +Peptidyl proline modification 0.4331750543926475 1.152348948448287 0.2491777103339567 1.0 0.9660593159673952 35 P62942,Q9Y237,Q96AY3,O95302,Q32P28,O75718,Q9Y680,Q9BV86,Q9NWM8,Q8IVL6,Q5T1M5 11 +Amino acid betaine transport 0.8839893459603441 1.1520504957467412 0.2493003239423019 1.0 0.9660593159673952 2 O43772 1 +Quaternary ammonium group transport 0.8839893459603441 1.1520504957467412 0.2493003239423019 1.0 0.9660593159673952 2 O43772 1 +Regulation of er to golgi vesicle mediated transport 0.5828126725842422 1.1517256982195931 0.2494338087337488 1.0 0.9660593159673952 6 Q9P2W9,Q9NR31 2 +Suppression of viral release by host 0.6639845210550931 1.149805551616294 0.2502239681781204 1.0 0.9660593159673952 4 Q12899,P19474 2 +Gtp metabolic process 0.4772640745646563 1.1495142157757885 0.2503440083457726 1.0 0.9660593159673952 15 O60313,Q8IWA4,Q13232 3 +Peptidyl arginine modification 0.5567885561417676 1.1492339047208042 0.2504595438848698 1.0 0.9660593159673952 8 O60678,Q6P2P2 2 +Rna stabilization 0.4310344616823718 1.1483445465009667 0.2508263562375707 1.0 0.9660593159673952 26 P67809,Q92804,Q14011,P98175,O60506,Q9H2U1,P35637,Q9H074 8 +Positive regulation of histone ubiquitination 0.6196077134823619 1.1478209784099025 0.2510424751392586 1.0 0.9660593159673952 5 Q5VTR2,O60341,O75150 3 +Negative regulation of amyloid beta clearance 0.882805563776267 1.1474789636009133 0.2511837224679869 1.0 0.9660593159673952 2 Q16850 1 +Heart process 0.4326987504341679 1.147402031385624 0.2512155020342534 1.0 0.9660593159673952 32 P78417,P0DP25,P16615,O75844,P09493,P00813 6 +Regulation of lipophagy 0.7473186543939825 1.1464595418050407 0.2516050583379288 1.0 0.9667778084624252 3 P42858 1 +Antigen processing and presentation of peptide antigen 0.4839869598441466 1.1455100595116106 0.2519979307701472 1.0 0.9671627900464012 14 Q6P179,Q9NZ08,Q9UIQ6,P50570,Q03518 5 +Aminoglycan biosynthetic process 0.5679446653327127 1.139637961832593 0.2544371629934101 1.0 0.970846802587999 7 Q8NCH0 1 +Positive regulation of dna methylation dependent heterochromatin assembly 0.5676872527822967 1.1383887318296295 0.2549581971542438 1.0 0.970846802587999 7 Q8NEY8 1 +Positive regulation of epithelial cell proliferation 0.4296906511998805 1.1376228210748962 0.255278013123958 1.0 0.970846802587999 26 P09601,P31749,Q9H2J4,Q6ZWJ1,Q9NQC3,P09429,P07942,Q15648 8 +Detection of visible light 0.7444766872616135 1.13535289210956 0.2562274890760854 1.0 0.970846802587999 3 Q9BV73 1 +Positive regulation of blood vessel endothelial cell migration 0.4886910551567637 1.1349972494846774 0.2563764708226483 1.0 0.970846802587999 13 P06576,P09601,P31749 3 +Regulation of anion transport 0.4822616649809814 1.134654947320374 0.2565199209428406 1.0 0.970846802587999 14 P55011,O43865,P14174 3 +Regulation of steroid biosynthetic process 0.510169527387418 1.1345068465154264 0.2565820034895596 1.0 0.970846802587999 11 P16435,P30536 2 +Golgi vesicle budding 0.5535523196083323 1.1329314862728057 0.2572430263033518 1.0 0.970846802587999 8 Q9H4A6,Q15363,P49755,Q9H4A5 4 +Cristae formation 0.553431266336589 1.1323217037322575 0.2574992086679517 1.0 0.970846802587999 8 Q9Y4W6,Q9NX63 2 +Placenta blood vessel development 0.5534086237475111 1.132207646264794 0.2575471462323411 1.0 0.970846802587999 8 P31749 1 +Negative regulation of b cell apoptotic process 0.6596086924233904 1.1315909432996578 0.2578064494587162 1.0 0.970846802587999 4 P00813 1 +Terpenoid biosynthetic process 0.57790752924612 1.1287558711648993 0.2590008329629545 1.0 0.970846802587999 6 P48449,O94788,O60678,O95749 4 +Negative regulation of mrna 3 end processing 0.5655812484424303 1.128168723500452 0.2592486699993976 1.0 0.970846802587999 7 Q5VTR2 1 +Maintenance of location in cell 0.4211127563713145 1.1279533942777538 0.2593396023560745 1.0 0.970846802587999 49 P62942,P31749,Q13438,P30536,P78417,O43731,P0DP25,Q9H4A6,P42858,Q8NEW0,P24390 11 +Regulation of neuron projection arborization 0.6586898346970864 1.1277677669120327 0.2594180095088219 1.0 0.970846802587999 4 O14641 1 +Cellular response to reactive nitrogen species 0.5653053168533393 1.1268297577032638 0.2598144663453532 1.0 0.970846802587999 7 Q99707,P20248,P50570,Q14103,O95831 5 +Response to nitric oxide 0.5653053168533393 1.1268297577032638 0.2598144663453532 1.0 0.970846802587999 7 Q99707,P20248,P50570,Q14103,O95831 5 +Response to mitochondrial depolarisation 0.5652821514383792 1.1267173477446326 0.2598620054135527 1.0 0.970846802587999 7 O43464,Q13501,P52789 3 +Pigment granule localization 0.6581285136794401 1.125432522099168 0.2604057962004211 1.0 0.9720734501780108 4 Q13561 1 +Negative regulation of macroautophagy 0.4805512475809187 1.1238923718707388 0.2610586877957521 1.0 0.9736358257479596 14 P09601,P31749 2 +Detection of stimulus 0.46501711178535 1.1229497078585762 0.2614588544768459 1.0 0.9736358257479596 16 P30536,Q9BV73,Q15555,P0DP25,Q8WTV0 5 +Regulation of biomineralization 0.522800714751205 1.1197525775067212 0.2628192128936879 1.0 0.9738266543791968 10 P20248,Q13464,O75844,Q4KMQ2,O75116,P22413 6 +Protein localization to synapse 0.4798427628014374 1.1194340822868474 0.262954997724016 1.0 0.9738266543791968 14 P33176,Q9UQB8,Q4V328,Q13277,Q14168 5 +C4 dicarboxylate transport 0.5371647952354813 1.11928825363409 0.2630171853634235 1.0 0.9738266543791968 9 Q9UBX3 1 +Protein polyubiquitination 0.4132483646949342 1.1174950991390935 0.2637826938838599 1.0 0.9747944889449212 54 O95155,Q7Z7E8,Q9UBS8,Q9Y4X5,Q05086,Q9UJX4,P55786,Q9UIQ6,P19474,P52888,Q5VTR2,Q9Y297,Q9BW61,O75150,Q9Y508 15 +Antigen processing and presentation 0.4274997624056576 1.1161264026964837 0.2643680319692754 1.0 0.974859510830581 27 Q9BZG1,Q9NZ08,Q06323,Q6P179 4 +Negative regulation of establishment of protein localization to mitochondrion 0.7393991449846561 1.1155292546148112 0.2646236892767533 1.0 0.974859510830581 3 P49257 1 +Regulation of adherens junction organization 0.7393051985664911 1.115162724569697 0.2647806963421593 1.0 0.9748944970057551 3 P35611 1 +Autophagosome membrane docking 0.8739271973956799 1.1132586990996531 0.2655973389225461 1.0 0.9761627715423212 2 P16615 1 +Endocytic recycling 0.4277845529075199 1.1120858617198532 0.2661012350054501 1.0 0.9761627715423212 29 Q9H223,Q96L92,P35609,Q9H3S7,O43752,Q9UID3,Q4V328,Q15286,Q96C92,Q567U6,O60826,Q96QK1 12 +Regulation of dephosphorylation 0.4281953589333269 1.1119513391222395 0.2661590731304679 1.0 0.9761627715423212 36 Q86XL3,P0DP25,O43768,P78318,P42858,Q96JB5 6 +Regulation of t cell differentiation 0.4895732274425679 1.1077323241654686 0.2679774350504449 1.0 0.9795701704913664 12 P09429,O96005,P00813 3 +Regulation of chondrocyte differentiation 0.653668176178777 1.106884845770418 0.2683437186330746 1.0 0.980366852651183 4 Q92896 1 +Axonal transport of mitochondrion 0.6093311577843364 1.102528815851589 0.2702318380270068 1.0 0.9859835236238268 5 P07196 1 +Nuclear transcribed mrna catabolic process exonucleolytic 0.469933355085649 1.101989346228386 0.2704663033233072 1.0 0.9859835236238268 15 Q6PGP7,Q13868,Q969T7 3 +Cerebellar cortex morphogenesis 0.5471993943636622 1.1009339227427084 0.2709254166894945 1.0 0.9859835236238268 8 Q7Z4L5,O15020 2 +Regulation of smad protein signal transduction 0.6520562281683568 1.1001857833296176 0.2712511835582318 1.0 0.986065103616332 4 Q8N1F7 1 +Regulation of protein targeting to membrane 0.4879902757511164 1.0982984193678988 0.2720742018983122 1.0 0.986065103616332 12 P31751 1 +Regulation of cellular response to osmotic stress 0.6514065391226652 1.0974863951159513 0.2724288248051709 1.0 0.986065103616332 4 O95202,Q9BPX6 2 +Amp biosynthetic process 0.503608860741345 1.0971373028010083 0.2725813757189865 1.0 0.986065103616332 11 P00813 1 +Sphingolipid mediated signaling pathway 0.7344154307281857 1.0960990249244318 0.273035441322861 1.0 0.986065103616332 3 P31749 1 +Blastocyst growth 0.5706448879836101 1.094761344053541 0.2736212057562301 1.0 0.986065103616332 6 P61201,Q9BRT9 2 +Regionalization 0.4252759525391547 1.0947411587145923 0.2736300513994161 1.0 0.986065103616332 28 Q7Z4L5,O94788,Q15363,O14641,Q8NCM8,Q8N2A8,Q5T9L3 7 +I kappab kinase nf kappab signaling 0.4093337826034395 1.094685531971573 0.273654429228334 1.0 0.986065103616332 55 Q13501,P62942,Q8WVQ1,P09601,Q8TB61,P31749,O75116,Q8IUD2,O43657,Q9H2U1,P29692,P19474,P32929,Q9Y297,P98194,Q86UE4,Q96HY6,Q5T9L3 18 +Labyrinthine layer morphogenesis 0.7338661930136183 1.0939594494418057 0.2739727633348294 1.0 0.986065103616332 3 Q15363,P62993 2 +L methionine salvage from methylthioadenosine 0.8688961231133491 1.0939229210801598 0.2739887850336413 1.0 0.986065103616332 2 Q13126 1 +Amino acid salvage 0.8688961231133491 1.0939229210801598 0.2739887850336413 1.0 0.986065103616332 2 Q13126 1 +Vascular associated smooth muscle cell proliferation 0.5178726598622876 1.0928638785662947 0.2744535698710222 1.0 0.986065103616332 10 P09601 1 +Endocrine system development 0.4682078544300032 1.0908016513907832 0.2753601696719938 1.0 0.986065103616332 15 O94788,P30536,P31749 3 +Cellular response to x ray 0.5691615525638846 1.0878213744449412 0.2766739715900046 1.0 0.986065103616332 6 P12956,Q9H1E3 2 +Protein localization to perinuclear region of cytoplasm 0.867120449837231 1.0871088564576847 0.2769887042624641 1.0 0.986065103616332 2 Q96ED9 1 +Cardiac ventricle development 0.4504410246508945 1.0847823663746503 0.278018057295879 1.0 0.986065103616332 17 O75844,P62942,P09493 3 +Positive regulation of jun kinase activity 0.6050911580517722 1.0838611051197422 0.278426387226331 1.0 0.986065103616332 5 O14641 1 +Regulation of histone h2b ubiquitination 0.6477219661866693 1.082184775628934 0.2791704319743391 1.0 0.986065103616332 4 Q5VTR2 1 +Negative regulation of release of cytochrome c from mitochondria 0.543316961508062 1.0813859686550995 0.2795254605169925 1.0 0.986065103616332 8 P10909,P31749 2 +Positive regulation of transport 0.372753429444088 1.077910514592423 0.2810736926240658 1.0 0.9874704099668926 194 P55011,O43633,O95563,Q9H4A5,P31751,Q08209,Q9Y282,Q15154,Q07666,Q03164,O14737,P42858,Q9Y5X3,Q9H3S7,Q9NR31,P10909,P30536,O75312,O00410,P31749,O00429,P78417,P33176,P55786,Q9H4A6,Q9C0E2,P15311,O43707,Q9H6U6,P98194,O43464,P12270,O43865,Q4KMQ2,P61978,Q99996,P16220,Q9P2W9,P49755,Q5T9L3,P35609,P14174,O14964,P35580,Q9GZY8,P0DP25,P06493,P50402,Q92544,Q96QK1 50 +Ventricular system development 0.5423552251615178 1.0765447506533457 0.2816836982542741 1.0 0.9874704099668926 8 Q7Z4L5 1 +Mitochondrion distribution 0.5664130939034498 1.0749659149740485 0.2823899889041708 1.0 0.9874704099668926 6 O75153 1 +Purine nucleoside triphosphate catabolic process 0.7289546911951751 1.0748431464708246 0.2824449595464937 1.0 0.9874704099668926 3 P00813 1 +Embryonic camera type eye development 0.8638650488310164 1.074631032726802 0.2825399523751541 1.0 0.9874704099668926 2 O94788 1 +Regulation of receptor signaling pathway via stat 0.5284952319369454 1.073889971530166 0.2828719985519909 1.0 0.9881083712632708 9 Q8WXW3,Q9NX40 2 +Pancreas development 0.4784097888708919 1.0720885259361002 0.2836802720050309 1.0 0.9882570024947372 13 Q5T9L3,P31749 2 +Definitive erythrocyte differentiation 0.8629772121929575 1.071231360524359 0.2840654139857697 1.0 0.9882570024947372 2 Q96JB5 1 +Regulation of neutrophil chemotaxis 0.5537576387069484 1.0708204086723565 0.2842501885453039 1.0 0.9882570024947372 7 O00429,Q00013 2 +Response to x ray 0.4833758049478258 1.070797844868376 0.2842603361692382 1.0 0.9882570024947372 12 P12956,Q9H1E3,Q70UQ0,P50570 4 +Regulation of regulated secretory pathway 0.4385524576960437 1.069655875095501 0.2847742346874731 1.0 0.9890031093271202 18 Q4J6C6,P09601,P0DP25 3 +Regulation of cardiac muscle cell action potential involved in regulation of contraction 0.8614974844628601 1.065568528310267 0.2866187322006936 1.0 0.9890530333310872 2 P16615 1 +Positive regulation of proteasomal ubiquitin dependent protein catabolic process 0.4219756734952632 1.0650070758605927 0.2868727277348037 1.0 0.9890530333310872 29 Q9UBS8,P10909,P31749,Q9Y4X5,Q8IXJ6,Q9Y5A7,Q9UMX0,Q9BW61,Q96HY6 9 +Intraciliary retrograde transport 0.8612015389168413 1.0644364606807792 0.2871310240589175 1.0 0.9890530333310872 2 Q7Z4L5 1 +Antigen processing and presentation of exogenous peptide antigen via mhc class i 0.7258387828063573 1.0627319200715326 0.2879035409810859 1.0 0.9895180936764978 3 Q03518 1 +Negative regulation of leukocyte apoptotic process 0.5637195396992914 1.062372310948632 0.2880666987794797 1.0 0.9895180936764978 6 P00813 1 +Negative regulation of lymphocyte apoptotic process 0.5637195396992914 1.062372310948632 0.2880666987794797 1.0 0.9895180936764978 6 P00813 1 +Regulation of nitric oxide metabolic process 0.4816679377850078 1.060620469858791 0.2888624160503354 1.0 0.9916300488003306 12 P10909,P30536 2 +Membrane biogenesis 0.4207650255131576 1.058373892340011 0.2898850171613725 1.0 0.9929037954799824 28 O43633,Q86XL3,Q8IXJ6,Q16739,Q01082 5 +Regulation of lymphocyte differentiation 0.4547637854587681 1.0543321104443213 0.2917308924062602 1.0 0.9929037954799824 16 P12956,P09429,O96005,P00813 4 +Negative regulation of dephosphorylation 0.4544656451624279 1.0523372717127877 0.2926448372005701 1.0 0.9929037954799824 16 P62942,O95429,O43768,O75116 4 +Regulation of proteasomal protein catabolic process 0.3623500984281655 1.0512617695448143 0.2931383804539376 1.0 0.9929037954799824 74 Q9Y4X5,P46379,Q9Y5A7,Q9Y297,P61289,Q9BW61,Q96KB5,P10909,P31749,Q06323,O15294,Q8N163,Q92990,Q04323,P49841,Q9UL46,Q9UMX0,O15372,Q96HY6,Q9UBS8,Q8IXJ6,P49069,O75150 23 +Import across plasma membrane 0.4149965859736019 1.05085986707565 0.2933229550453602 1.0 0.9929037954799824 21 P55011,P31749,P30825,P31751 4 +Negative regulation of catabolic process 0.3210606862486723 1.048487560674471 0.2944140304999609 1.0 0.9929037954799824 106 Q9H2J4,P46379,Q9H074,P42704,Q96KB5,Q07820,Q16850,P30536,P31749,Q08379,Q13257,O15294,P67809,Q8N163,P09601,Q04323,P98175,Q14011,O60506,Q9H2U1,Q99729,Q08J23,P49815,O15372,Q96JB5,Q96HY6,Q92804,Q8IXJ6,P35637,Q9NNW5,P49069,Q96QK1 32 +Synaptic vesicle exocytosis 0.4353315899283062 1.0465514390340815 0.2953065088073456 1.0 0.9929037954799824 18 Q4J6C6,P16615,O95721,P0DP25 4 +Regulation of response to osmotic stress 0.5964255916808416 1.045756561535742 0.2956734411821831 1.0 0.9929037954799824 5 O95202,Q9BPX6 2 +Positive regulation of proteolysis involved in cellular protein catabolic process 0.4174325402304015 1.0450788608546455 0.295986523224069 1.0 0.9929037954799824 43 Q9UBS8,P10909,Q9Y4X5,P31749,P49841,Q8IXJ6,P46379,Q96JB5,Q9Y5A7,O60826,Q9UMX0,Q9BW61,O75150,Q96HY6 14 +B cell homeostasis 0.5599492706641573 1.0447542798674323 0.2961365506937661 1.0 0.9929037954799824 6 P00813,P14174 2 +Positive regulation of inclusion body assembly 0.6386655740545952 1.044634900358098 0.2961917429593219 1.0 0.9929037954799824 4 P10909 1 +Neuromuscular synaptic transmission 0.855874519088489 1.0440885370960693 0.296444428809506 1.0 0.9929037954799824 2 O60333 1 +Muscle organ development 0.4173163259886104 1.0440517953912445 0.2964614265406404 1.0 0.9929037954799824 43 P62942,Q08209,Q7Z406,Q8IXJ6,P61201,Q9BRT2,P50402,P09493,P60660,P16220,Q15648 11 +Retinoic acid metabolic process 0.7206522863221938 1.0426029884677628 0.2971322045971871 1.0 0.9929037954799824 3 O94788 1 +Epithelial cell proliferation 0.4066840571666053 1.0405120124998015 0.2981020860550909 1.0 0.9929037954799824 53 P57105,P09601,P31749,Q00577,Q9H2J4,O94788,Q6ZWJ1,Q9NQC3,P09429,P07942,Q9Y297,Q15418,Q8WTV0,Q15648 14 +Forebrain neuron differentiation 0.5948353248244458 1.0387719927225298 0.2989107898147856 1.0 0.9929037954799824 5 O14949 1 +Hepatocyte growth factor receptor signaling pathway 0.5471305619095516 1.0387135986161349 0.2989379548402238 1.0 0.9929037954799824 7 Q8IXJ6 1 +Hindbrain morphogenesis 0.4932361530329243 1.0380690443378386 0.2992379119259865 1.0 0.9929037954799824 11 Q7Z4L5,O15020 2 +Regulation of smoothened signaling pathway 0.4664269097321704 1.0350161233088084 0.3006613815078534 1.0 0.9929037954799824 14 Q7Z4L5,Q9BZG1,Q8NCM8,P16435,Q9Y297 5 +Pigment metabolic process 0.4176014319338307 1.032873920814689 0.3016629046755574 1.0 0.9929037954799824 28 P09601,P30536,Q9Y4G8,P30519,P00813 5 +Intrinsic apoptotic signaling pathway in response to oxidative stress 0.4334207673222037 1.0328475078154689 0.3016752671336054 1.0 0.9929037954799824 18 O43464,P31749,Q9NR28,P23246,Q9UMX0,Q15233 6 +Forebrain neuron development 0.63581227429366 1.0328246939266277 0.301685945319424 1.0 0.9929037954799824 4 O14949 1 +Aerobic respiration 0.3108779458520962 1.031961967206612 0.3020899347166177 1.0 0.9929037954799824 92 P00846,O75964,Q9UDW1,Q13423,P22695,P03886,O43676,P14406 8 +Embryonic pattern specification 0.533455299522786 1.0317728718302082 0.302178530563939 1.0 0.9929037954799824 8 Q8N2A8,Q15363 2 +Cytoskeleton dependent intracellular transport 0.3791883285029452 1.0305716258458733 0.3027417476631224 1.0 0.9929037954799824 67 Q9Y2T2,Q15154,Q96ED9,O60313,P42858,P42704,Q8WXH0,O75381,O94901,P33176,O60333,Q8TD16,Q92572,O43707,Q14203,Q00577,O00159,O43805,Q8NCM8,Q7Z4L5,P07196,A0AVF1,P23246,Q14168 24 +Toll like receptor 9 signaling pathway 0.8523231725362551 1.0305552814827244 0.3027494157043957 1.0 0.9929037954799824 2 Q9NQC3 1 +Regulation of toll like receptor 9 signaling pathway 0.8523231725362551 1.0305552814827244 0.3027494157043957 1.0 0.9929037954799824 2 Q9NQC3 1 +Positive regulation of toll like receptor 9 signaling pathway 0.8523231725362551 1.0305552814827244 0.3027494157043957 1.0 0.9929037954799824 2 Q9NQC3 1 +Positive regulation of chemokine c x c motif ligand 2 production 0.8523231725362546 1.030555281482722 0.3027494157043968 1.0 0.9929037954799824 2 P14174 1 +Chemokine c x c motif ligand 2 production 0.8523231725362546 1.030555281482722 0.3027494157043968 1.0 0.9929037954799824 2 P14174 1 +Muscle cell proliferation 0.4165232940231156 1.0280943842134656 0.303905432019607 1.0 0.9929037954799824 27 P09601,P09493,P31749 3 +Regulation of release of sequestered calcium ion into cytosol 0.4709519429193161 1.0264674558993916 0.3046712960555058 1.0 0.9929037954799824 13 P78417,P0DP25,P42858 3 +Regulation of calcium ion transport into cytosol 0.4709519429193161 1.0264674558993916 0.3046712960555058 1.0 0.9929037954799824 13 P78417,P0DP25,P42858 3 +Regulation of cell maturation 0.8511393903521772 1.0260501260401405 0.3048679571732944 1.0 0.9929037954799824 2 Q8IXJ6 1 +Secretory granule localization 0.7161399116271794 1.0251236529505492 0.3053048462856065 1.0 0.9929037954799824 3 P33176 1 +Negative regulation of actin filament depolymerization 0.4415940517274402 1.023560182821156 0.3060430601278452 1.0 0.9929037954799824 17 Q13045,Q9BPX3,Q13813,P35611,P35612,Q9NYL9,Q9UEY8,O15020,Q01082 9 +Signal transduction in absence of ligand 0.4644210880407813 1.02240083628052 0.3065912248813431 1.0 0.9929037954799824 14 O43464,Q07820,O95677,P31749,P49841,P30154 6 +Response to peptide hormone 0.3115170253506264 1.0220024777927696 0.3067797276805526 1.0 0.9929037954799824 94 Q16836,P31751,Q9H1E3,Q8TBX8,Q86YS7,Q9Y266,Q5VZ89,P11802,Q9Y5X3,P31749,P35613,Q6ZWJ1,Q92572,Q7L576,P43490,O15294,P49841,Q9UQB8,O43865,P25054,O00159,P16435,O75116,P16220,P49815,P62993,P35609,P07196,P49770,O60763,Q9BSK2,O75150 32 +Regulation of synaptic vesicle recycling 0.5315006010679568 1.0219483148218356 0.3068053634667558 1.0 0.9929037954799824 8 Q7L576,P0DP25 2 +Regulation of collateral sprouting 0.7152161042036775 1.0215492028387525 0.3069943102530525 1.0 0.9929037954799824 3 P53990,Q8N0X7 2 +Regulation of glycogen metabolic process 0.5549031549820169 1.0211952009105798 0.3071619656090898 1.0 0.9929037954799824 6 P31751 1 +Regulation of glucan biosynthetic process 0.5549031549820169 1.0211952009105798 0.3071619656090898 1.0 0.9929037954799824 6 P31751 1 +Prostate gland growth 0.7144205001348192 1.0184719456611933 0.3084537265380453 1.0 0.9929037954799824 3 Q05086 1 +Positive regulation of potassium ion transmembrane transporter activity 0.5901504582231455 1.0182128969196398 0.3085767917310367 1.0 0.9929037954799824 5 P35609,Q99996,P50570 3 +Protein autoprocessing 0.5901348789896806 1.0181445743072868 0.308609254876635 1.0 0.9929037954799824 5 O43464,Q9Y4W6 2 +Response to glucagon 0.7143280047365388 1.018114258835646 0.3086236598438172 1.0 0.9929037954799824 3 P20248,P16220 2 +Response to axon injury 0.4312808802964766 1.017504554073014 0.3089134669348492 1.0 0.9929037954799824 18 P07196,Q99707,Q96G23,P30536,P00374,P10586 6 +Response to cell cycle checkpoint signaling 0.7140250409661597 1.0169427761381296 0.3091806524668619 1.0 0.9929037954799824 3 O75844 1 +Atp biosynthetic process 0.4095129557131425 1.0159522662586689 0.3096521178625151 1.0 0.9929037954799824 20 P00846,O75964,P00403 3 +Positive regulation of chromosome condensation 0.5887964417441071 1.012276053453894 0.3114060812006656 1.0 0.9932832001231654 5 Q9BPX3,Q9NTJ3 2 +Modification of postsynaptic structure 0.5408739317557077 1.0084383904775067 0.3132440506159348 1.0 0.9952423868247728 7 Q9UQB8 1 +Dendritic cell chemotaxis 0.629769760359249 1.0078505813880416 0.3135261990269598 1.0 0.9952423868247728 4 Q4KMQ2,P09429 2 +Small gtpase mediated signal transduction 0.3111797467550374 1.0073699688813191 0.3137570173129749 1.0 0.9954969406728044 95 P57105,Q9Y4G8,Q96RU2,P80303,Q5VZ89,Q9NUQ9,Q15392,Q7L576,O15294,P53365,Q13501,P09601,Q9UN86,Q15047,O75116,P49815,Q96RT1,P16949,Q15555,Q9Y2I1,Q15058 21 +Negative regulation of mrna catabolic process 0.4114292837721635 1.002823194041566 0.3159461758543762 1.0 0.9990852996275466 24 P67809,Q92804,Q14011,P98175,O60506,P35637,Q9H074 7 +Modified amino acid transport 0.5275256934321323 1.001982191778985 0.3163521938238602 1.0 0.9998907933916272 8 O43772,Q9H2D1 2 +Negative regulation of blood circulation 0.7096929777838871 1.000209247459856 0.3172092549385508 1.0 1.0 3 P16615 1 +Regulation of multicellular organism growth 0.4464427543437499 0.998681332857474 0.3179490863093326 1.0 1.0 16 O43464,Q9HCL2,Q9Y4W6,O75844,P15311,P16220,O95470 7 +Phenol containing compound catabolic process 0.8431488606096493 0.995721894454795 0.3193852890395412 1.0 1.0 2 P16930 1 +Circulatory system process 0.3483284825864081 0.9907014682294168 0.3218313739403438 1.0 1.0 77 P09601,Q6P179,Q9NZ08,P78417,P0DP25,P16615,O75844,P30825,P09493,P00813,P42785 11 +Regulation of mitochondrial fusion 0.5834584603818118 0.9888958201117144 0.3227141158244526 1.0 1.0 5 Q8N2A8 1 +Muscle hypertrophy in response to stress 0.6250209714367252 0.988262076122261 0.3230243134355079 1.0 1.0 4 P16615,Q08209 2 +Positive regulation of wnt signaling pathway 0.4078052010861731 0.9874504063623476 0.3234218839160174 1.0 1.0 22 Q7Z4L5,Q5T9L3 2 +Chemical homeostasis 0.3634991951230416 0.9873765363678796 0.3234580825970385 1.0 1.0 188 P55011,P62942,O95563,Q08209,Q9Y4W6,Q9H1E3,P30519,Q9NQC3,Q96A33,P42858,Q16739,Q8NEW0,Q9BPX6,Q9Y5X3,Q96TC7,P52789,P0CG08,P05023,P30536,P31749,Q6ZWJ1,P78417,Q9HC07,Q93050,Q9Y6M7,Q8IYU8,P06576,Q14BN4,Q9Y6C9,Q8WTV0,P09601,Q9HCL2,Q9Y487,Q5BJF2,Q05086,Q8N511,O15254,Q9HD20,O75880,P16949,Q86YV9,Q15067,Q6P4Q7,P0DP25,P16615,P09429,Q9NWR8,O15260,P42785 49 +Bone development 0.4121511894616473 0.9854239224380344 0.3244158837268951 1.0 1.0 29 Q7RTS9,Q15125,Q9NX62,Q32P28,O75844,Q92896 6 +Positive regulation of receptor signaling pathway via stat 0.8401894051494543 0.984527008514859 0.3248564585142202 1.0 1.0 2 Q8WXW3 1 +Regulation of proteasomal ubiquitin dependent protein catabolic process 0.3994183770480022 0.984228452655558 0.3250031990460627 1.0 1.0 54 Q96KB5,Q8N163,Q92990,P10909,Q9Y4X5,P31749,Q04323,Q9UBS8,P46379,Q8IXJ6,Q9Y5A7,P49069,Q9UMX0,O15372,Q9BW61,Q96HY6,O15294 17 +Forebrain generation of neurons 0.5467117340981912 0.983014018471083 0.3256005392657828 1.0 1.0 6 O14949 1 +Negative regulation of lymphocyte migration 0.8393015685113956 0.9811727082795172 0.3265075802294355 1.0 1.0 2 P31749 1 +Cellular response to oxidised low density lipoprotein particle stimulus 0.8393015685113956 0.9811727082795172 0.3265075802294355 1.0 1.0 2 P31749 1 +Response to angiotensin 0.5459453565012994 0.9794464435577876 0.3273594387377954 1.0 1.0 6 P35609,O43865 2 +Positive regulation of bone mineralization 0.6227420787681291 0.9788749172708024 0.3276417870070776 1.0 1.0 4 Q4KMQ2,P20248,P20020 3 +Positive regulation of biomineralization 0.6227420787681291 0.9788749172708024 0.3276417870070776 1.0 1.0 4 Q4KMQ2,P20248,P20020 3 +Regulation of monooxygenase activity 0.4967888742325932 0.9779647796396086 0.3280917438965942 1.0 1.0 10 Q8TCT9,P31749,P0DP25,P16435,Q8WTV0 5 +Regulation of response to interferon gamma 0.703618638757792 0.9768038121304776 0.3286662884293636 1.0 1.0 3 Q15648 1 +Voluntary musculoskeletal movement 0.622194524902145 0.9766207815141764 0.3287569268899677 1.0 1.0 4 Q96QK1,P78559 2 +Dendritic cell migration 0.5804157137226857 0.9755878303686972 0.3292687576437603 1.0 1.0 5 Q4KMQ2,P09429 2 +Positive regulation of adaptive immune response 0.4346423474021875 0.9755021497664884 0.3293112358473733 1.0 1.0 17 Q9NUQ9 1 +Negative regulation of proteasomal ubiquitin dependent protein catabolic process 0.4052295583424987 0.974777113972482 0.3296708317902237 1.0 1.0 21 Q96KB5,Q8N163,P46379,P49069,O15372,Q96HY6,O15294 7 +Positive regulation of striated muscle contraction 0.8375258952352794 0.9744699977000428 0.3298232288762999 1.0 1.0 2 P78417 1 +Negative regulation of hormone metabolic process 0.8375258952352784 0.9744699977000392 0.3298232288763016 1.0 1.0 2 O60678 1 +Regulation of steroid hormone biosynthetic process 0.8375258952352781 0.9744699977000374 0.3298232288763025 1.0 1.0 2 P16435 1 +Regulation of hormone biosynthetic process 0.8375258952352781 0.9744699977000374 0.3298232288763025 1.0 1.0 2 P16435 1 +Glutamate receptor signaling pathway 0.6215657859412467 0.9740330799257542 0.3300401146083382 1.0 1.0 4 Q06787,Q8NCG7 2 +Regulation of intracellular transport 0.3257827458475173 0.9718553394710172 0.3311225205312065 1.0 1.0 122 P31751,Q9Y282,Q15154,Q07666,P49257,O14737,Q9H3S7,Q9NR31,O75312,O00410,Q13438,P55786,Q9C0E2,P15311,O95429,Q9H6U6,O43464,P49841,P12270,Q08J23,Q9P2W9,Q7Z4L5,P35609,Q4V328,Q9GZY8,P06493,P50402,Q92544,Q96QK1 29 +Negative regulation of inflammatory response 0.4496237000061858 0.97039799001282 0.3318481501865296 1.0 1.0 15 P28070 1 +Membrane fusion 0.4059551250334809 0.9700400034149768 0.3320265525995149 1.0 1.0 47 O95249,P31751,O00429,O43752,O95721,Q13277,Q9BZG1,Q15075,Q13190,Q12981,Q8IWA4,Q15276,Q9P2W9 13 +Pirna metabolic process 0.8357502219591612 0.9677752703942883 0.3331566168728601 1.0 1.0 2 Q8N2A8 1 +Cardiac muscle contraction 0.4052478439291368 0.967457507876224 0.333315373473235 1.0 1.0 22 P78417,P0DP25,P09493 3 +Response to cisplatin 0.835158330867123 0.9655454958715312 0.3342716598571498 1.0 1.0 2 P09601 1 +Negative regulation of translational initiation 0.5198676814149995 0.9635714217942812 0.335260840405621 1.0 1.0 8 Q06787,P12270,Q9BWF3,P05198,Q9BPZ3 5 +Negative regulation of t cell apoptotic process 0.7000299462939777 0.9630100897197866 0.335542459877697 1.0 1.0 3 P00813 1 +Protein o linked glycosylation via serine 0.6994948084991186 0.960955479538286 0.3365745534487026 1.0 1.0 3 Q10472 1 +Deoxyribose phosphate metabolic process 0.4647455594421912 0.9598788352086128 0.3371161993484421 1.0 1.0 12 Q9H773,P00813,P31350 3 +Positive regulation of protein localization to membrane 0.4099653005084001 0.9592327395995708 0.337441510621054 1.0 1.0 37 Q13501,P31749,P33176,P31751,Q13277,Q9GZY8,P15311,O14737,O00264,Q01082 10 +Regulation of cartilage development 0.5761583869242616 0.9569934507494712 0.3385705606722065 1.0 1.0 5 Q92896 1 +Positive regulation of non motile cilium assembly 0.5408721785534577 0.955852986719282 0.339146513901734 1.0 1.0 6 Q66GS9,Q9P2S5 2 +Positive regulation of actin cytoskeleton reorganization 0.5408197721937135 0.9556094821501552 0.3392695691291068 1.0 1.0 6 Q9UQB8 1 +Tripartite regional subdivision 0.6164439311700657 0.9529800608186724 0.340600173378764 1.0 1.0 4 Q8N2A8 1 +Establishment of mitochondrion localization 0.4782074198885066 0.9526291100633142 0.3407780226273436 1.0 1.0 11 O60313,P07196 2 +Proton transmembrane transport 0.4067011214550983 0.950290345908238 0.3419647429486718 1.0 1.0 43 P00846,O75964,Q9UDW1,Q13423,P00403,P06576,P13073 7 +Secretion 0.3494906261941365 0.950199471658958 0.3420109070573989 1.0 1.0 166 P55011,O43633,Q16836,O95563,Q9H4A5,Q08209,Q13505,O43768,Q9UBV2,Q5JRA6,Q9Y5X3,Q16850,P52789,Q7Z7E8,Q9H3S7,O00429,Q6ZWJ1,O95721,Q32P28,Q13277,Q9UNH7,Q9H4A6,P15311,P00813,Q15648,P09601,Q96KC8,P61201,Q13555,P00403,Q9Y2G5,P16220,P49755,Q9BRT2,Q5T9L3,P14174,Q96A65,O43760,Q4J6C6,Q86YV9,O14964,P35580,P55327,P0DP25,P16615,P35579,Q9BRK5,Q96PC5 48 +Morphogenesis of embryonic epithelium 0.4080667833366345 0.9492135416889486 0.3425120156086219 1.0 1.0 30 O15031,O94788,O60313,Q15363,O14641,P49815,Q8N3R9 7 +Astrocyte differentiation 0.4582406581871047 0.9488182539649012 0.3427130562280982 1.0 1.0 13 P08670 1 +Sulfur amino acid metabolic process 0.5045318155246183 0.9486927003615416 0.3427769277091188 1.0 1.0 9 Q13126,Q9BV57,Q99707 3 +Positive regulation of neuron differentiation 0.5044865123977735 0.9484567025599304 0.3428970048233246 1.0 1.0 9 Q8WUJ1 1 +Thyroid hormone mediated signaling pathway 0.8301272565847907 0.9466297685766292 0.3438274693600587 1.0 1.0 2 P42785 1 +Connective tissue replacement 0.6955641081741732 0.9458827586091992 0.3442083883451849 1.0 1.0 3 Q08209 1 +Positive regulation of tissue remodeling 0.6955641081741732 0.9458827586091992 0.3442083883451849 1.0 1.0 3 Q08209 1 +Regulation of connective tissue replacement 0.6955641081741732 0.9458827586091992 0.3442083883451849 1.0 1.0 3 Q08209 1 +Positive regulation of connective tissue replacement 0.6955641081741732 0.9458827586091992 0.3442083883451849 1.0 1.0 3 Q08209 1 +Negative regulation of peptidyl tyrosine phosphorylation 0.4767950854707382 0.9446147617919154 0.3448555878857451 1.0 1.0 11 Q8WXW3,O95684,Q9BRG1 3 +Regulation of dna methylation dependent heterochromatin assembly 0.516044453267327 0.9444280074686324 0.3449509748854795 1.0 1.0 8 Q8NEY8 1 +Regulation of peptidyl threonine phosphorylation 0.4767371201018488 0.9442859050764638 0.3450235666505197 1.0 1.0 11 Q8IXJ6 1 +Regulation of glucose transmembrane transport 0.4382853916103242 0.9442070067865744 0.345063875358147 1.0 1.0 16 O75298,P52789,P31749,P31751,Q6ZWJ1,Q16625 6 +Regulation of protein localization to cilium 0.5731969426352763 0.944078136020895 0.345129721190454 1.0 1.0 5 Q10713,Q96C92 2 +Cotranslational protein targeting to membrane 0.4519515045062562 0.9440723683572532 0.3451326683348206 1.0 1.0 14 P43307 1 +Interferon gamma mediated signaling pathway 0.5725795822599795 0.941387824364338 0.34650615082088 1.0 1.0 5 Q15648 1 +Regulation of keratinocyte proliferation 0.5268924912277564 0.940966646422517 0.3467219518369806 1.0 1.0 7 Q6ZWJ1,O14936,Q15648 3 +Keratinocyte proliferation 0.5268924912277564 0.940966646422517 0.3467219518369806 1.0 1.0 7 Q6ZWJ1,O14936,Q15648 3 +Regulation of lymphocyte apoptotic process 0.4756588461554163 0.9381695437344022 0.3481572873569529 1.0 1.0 11 P00813 1 +Purine nucleoside metabolic process 0.5025099585683795 0.9381636931622948 0.3481602935358352 1.0 1.0 9 O60725,P00813 2 +Positive regulation of reproductive process 0.5363820852441266 0.9350074764318104 0.3497844464409545 1.0 1.0 6 Q9H6S0,Q8IXJ6 2 +Protein localization to vacuole 0.4019516810495633 0.9346388002354962 0.3499744761149126 1.0 1.0 23 Q9H3S7,P10909,O75116,Q9Y2T2,O14964,Q9NQC3,P11142,Q9BRG1,Q9H9H4 9 +Positive regulation of amyloid beta formation 0.6912310689504065 0.929307214712591 0.3527298973071613 1.0 1.0 3 P10909 1 +Digestion 0.4494587459188608 0.9284424753386226 0.3531780941709439 1.0 1.0 14 Q16739,Q8WTV0 2 +Regulation of attachment of spindle microtubules to kinetochore 0.500587325296388 0.9281582583068524 0.3533254832673289 1.0 1.0 9 Q8IXJ6 1 +Intracellular mrna localization 0.8250961823024581 0.9277834967026942 0.3535198863546851 1.0 1.0 2 Q9H2U1 1 +Membrane organization 0.3865982460264547 0.9267094863240176 0.3540773908413877 1.0 1.0 248 P31751,Q13505,P46379,Q8N8Q8,Q9NS69,O43681,Q13190,Q12981,Q16739,Q5JRA6,P52789,P30536,Q53H12,Q15392,P98194,Q86XL3,Q5HYI7,Q15075,Q4KMQ2,Q15629,Q9P2W9,Q8IXJ6,O43760,O14964,O60763,Q9H4A5,Q9BVK6,Q7L5D6,Q9NQC3,Q9NPA0,Q9BZG1,P50542,P50570,O14737,O95202,P31749,P10909,O43752,O94901,Q14203,P49841,Q9UQB8,Q9UH99,Q9H6H4,Q9NQX3,Q9Y5L4,P0DP25,P02545,P16615,O75844,P50402,Q14696,Q9Y6B6,O43633,Q9Y5J7,Q9Y5J9,Q96A33,O60313,O95249,O00429,Q9H4A6,Q8N1F7,Q9NX63,P45880,Q14849,P35579,Q8IWA4,Q8N3R9,O60220,Q9Y4W6,Q8NHH9,Q9NR31,O95721,Q13277,Q15363,Q01082,Q15437,Q15276,P49755,P17152,Q8WUX9,P49069,O15027 83 +Regulation of oxidoreductase activity 0.418508518770454 0.926067070889698 0.354411125489976 1.0 1.0 18 Q8TCT9,P31749,Q9P0J1,P0DP25,P16435,Q8WTV0 6 +Protein k48 linked deubiquitination 0.4870906733156522 0.9252822703327952 0.3548190986808643 1.0 1.0 10 Q9Y4E8 1 +Negative regulation of signaling receptor activity 0.5342351776142511 0.92505361920551 0.3549380171546747 1.0 1.0 6 Q9BRG1,P30533 2 +Positive regulation of stem cell differentiation 0.608788753936766 0.9216112426227684 0.356731392093782 1.0 1.0 4 Q9Y6C9 1 +Process utilizing autophagic mechanism 0.3484203573776617 0.9191846950154025 0.3579989750572907 1.0 1.0 168 O43633,Q5MNZ6,Q8TBX8,P42858,Q9Y5X3,Q07820,P52789,P10909,P30536,P31749,O00429,O95721,Q08379,Q93050,Q9UNH7,P19474,Q9H6U6,P21796,Q86UE4,Q9Y4P1,O43464,Q9Y6I9,P53365,Q13501,P09601,Q9Y487,Q9UMX0,P49815,Q96HY6,Q96A65,Q8IXJ6,Q9UID3,O14681,O14964,Q9NNW5,P07602,P16615,O75844,Q8WUX9,P09429,O15027,Q9Y5K8,Q9BRG1,Q969Q5 44 +Actin myosin filament sliding 0.8224326723882832 0.9178354629919696 0.3587050130788292 1.0 1.0 2 P09493 1 +Angiogenesis involved in wound healing 0.6076479344451384 0.916947283029181 0.3591702652488751 1.0 1.0 4 P42785 1 +Regulation of fatty acid beta oxidation 0.5669534371122867 0.9169058471464576 0.3591919797159164 1.0 1.0 5 P31751 1 +Regulation of chromatin assembly or disassembly 0.4412844264576495 0.916509518943082 0.3593997171243408 1.0 1.0 15 P12270,Q8NEY8,Q9UPP1 3 +Regulation of p38mapk cascade 0.6874169453564585 0.9147533647282844 0.3603211221896807 1.0 1.0 3 P15311 1 +Meiotic spindle organization 0.5319496145296505 0.9144670512526222 0.3604714833310896 1.0 1.0 6 Q08379 1 +Pyridine nucleotide biosynthetic process 0.687259679589915 0.9141540372112604 0.3606359116643414 1.0 1.0 3 P43490 1 +Activation of cysteine type endopeptidase activity involved in apoptotic process 0.4524531203222914 0.913543424011405 0.3609568062230046 1.0 1.0 13 O95831,Q96A26,Q9NR28 3 +Regulation of chromatin assembly 0.4469588618927051 0.9127805714178876 0.3613579584788455 1.0 1.0 14 P12270,Q8NEY8,Q9UPP1 3 +Relaxation of cardiac muscle 0.6868852930938703 0.9127275276349368 0.3613858623752684 1.0 1.0 3 P05023 1 +Heart trabecula morphogenesis 0.6867401193528242 0.9121744723238354 0.3616768798302523 1.0 1.0 3 P62942 1 +Regulation of macroautophagy 0.3875720274476541 0.912140304557796 0.3616948637099244 1.0 1.0 57 O15269,Q15382,Q8TBX8,P61421,Q9Y2S7,P42858,Q9Y5X3,P31749,Q9H2M9,Q93050,Q9UNH7,P21796,P09601,Q9Y487,P49815,Q9UMX0,P21281,Q9UI12,Q96A65,Q9NQ88,Q9Y5K8,Q96QK1 22 +Regulation of receptor localization to synapse 0.6866275557791406 0.9117456853838528 0.361902608388005 1.0 1.0 3 Q4V328 1 +Amyloid fibril formation 0.4963430888349989 0.906096916129184 0.3648845574701078 1.0 1.0 9 P62942,P10909,O15212 3 +Postsynaptic modulation of chemical synaptic transmission 0.6046598788694739 0.9047455319606822 0.3656002133904894 1.0 1.0 4 Q7L576 1 +Attachment of spindle microtubules to kinetochore 0.3962112960331421 0.904691003634112 0.3656291084721395 1.0 1.0 21 Q8IXJ6,P25054,Q8NBT2 3 +Cellular response to peptide 0.3186563231977572 0.90453993413382 0.3657091690900533 1.0 1.0 84 P31751,Q9H1E3,Q8TBX8,Q5VZ89,Q9Y5X3,P31749,Q6ZWJ1,Q9UNS1,Q9UNH7,Q92572,Q7L576,P43490,O15294,P49841,Q9UQB8,O43865,P25054,P08670,O00159,P16435,O75116,P49815,P35609,O60763,Q9BSK2 25 +Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress 0.4239554559135313 0.9017888279098476 0.3671690556495379 1.0 1.0 17 P46379,O95831 2 +Regulation of metal ion transport 0.3759200867990955 0.9017443401159646 0.3671926930924325 1.0 1.0 63 P35609,P62942,Q14BN4,P05023,P31749,P30536,P33176,O43865,P78417,Q13555,P0DP25,Q99996,O43707,P42858,Q9UMX0,P21796 16 +Cerebral cortex development 0.4024298936273379 0.900570650639719 0.3678166452442131 1.0 1.0 31 Q96P11,P07196,O94901,P49841,Q96QD8,P62995,Q9NQC3,Q96N66,P50542,P07942,Q15058,Q8WXH0,Q8N3R9 13 +Positive regulation of granulocyte chemotaxis 0.56318975313986 0.9005664193998707 0.3678188958329946 1.0 1.0 5 O00429 1 +Positive regulation of neutrophil migration 0.56318975313986 0.9005664193998707 0.3678188958329946 1.0 1.0 5 O00429 1 +Reactive nitrogen species metabolic process 0.4149309179192386 0.900518913188374 0.3678441648891746 1.0 1.0 18 O43169,P30536,P10909,P31749 4 +Regulation of necrotic cell death 0.4682820673479764 0.8963851804229336 0.3700470794544026 1.0 1.0 11 P00403,P30536 2 +Dephosphorylation 0.3048600279270519 0.8949199809181221 0.3708298648274881 1.0 1.0 97 P62942,Q08209,Q9NX62,O43768,Q9BRF8,Q969T7,Q10713,P42858,Q9Y297,P10586,Q9H3S7,P05023,P30154,Q9NPH0,Q7Z4H3,Q86XL3,Q13555,Q6IN85,Q96JB5,O95677,Q9P0J1,P0DP25,P78318 23 +Maintenance of dna repeat elements 0.6018806071570676 0.8934154720344302 0.3716347200936873 1.0 1.0 4 O75844 1 +Protein k11 linked ubiquitination 0.5058031662734485 0.8932840462164445 0.3717050793480114 1.0 1.0 8 Q9UJX4 1 +Water homeostasis 0.481097641686339 0.8928144761026994 0.3719565327717773 1.0 1.0 10 Q16739 1 +Hormone metabolic process 0.40047459992026 0.8910618201711198 0.3728960060564263 1.0 1.0 29 P05023,P30536,Q14849,O94788,O60678,O75844,Q6NUM9,P16435,O95470 9 +Purinergic nucleotide receptor signaling pathway 0.6811850022075494 0.8910522648147278 0.3729011320234607 1.0 1.0 3 P00813 1 +Mating 0.5162478123501026 0.8898299395785743 0.3735572077448563 1.0 1.0 7 P00813 1 +Positive regulation of amyloid precursor protein catabolic process 0.5261673427169973 0.8877345430436238 0.3746835601876275 1.0 1.0 6 Q96P70,P10909 2 +Ear development 0.398163891531696 0.886381547034929 0.3754119594401515 1.0 1.0 26 Q8IZL8,Q9Y6M7,O95677 3 +Protein ufmylation 0.6001021854248537 0.8861755678736376 0.3755229271005573 1.0 1.0 4 Q96HY6 1 +Negative regulation of phosphatidylinositol 3 kinase signaling 0.6000996581175031 0.8861652849984711 0.375528467350088 1.0 1.0 4 P49815 1 +Forebrain cell migration 0.4478013946095286 0.885242630584924 0.3760257843438315 1.0 1.0 13 O94901,Q9NQC3,P50542,P07942,Q8WXH0 5 +Monoubiquitinated protein deubiquitination 0.4922678257599319 0.8849508250865643 0.3761831540756697 1.0 1.0 9 Q96K76 1 +Regulation of striated muscle contraction 0.4293164330097246 0.8844693759064504 0.3764428868587246 1.0 1.0 16 P16615,P78417,Q99996,P0DP25 4 +Vacuolar proton transporting v type atpase complex assembly 0.813258360461678 0.8837351517438967 0.3768391999829585 1.0 1.0 2 Q8N511 1 +Proton transporting v type atpase complex assembly 0.813258360461678 0.8837351517438967 0.3768391999829585 1.0 1.0 2 Q8N511 1 +Necrotic cell death 0.4291995745106731 0.8836924450578906 0.3768622597427362 1.0 1.0 16 O00429,P00403,P30536 3 +Connective tissue development 0.3976280096155055 0.8821289191246671 0.3777070950891297 1.0 1.0 26 P43490,O15173,Q9NX62,O75844,P16435,Q92896,Q96HY6 7 +Regulation of protein localization to synapse 0.6788040260509175 0.8820241674464937 0.377763738275966 1.0 1.0 3 Q4V328,Q12959 2 +Monocyte differentiation 0.5143379495475979 0.8806816443498994 0.3784901545194246 1.0 1.0 7 P35579,O00625 2 +Crd mediated mrna stabilization 0.4912836628356339 0.8798500237974176 0.378940561214574 1.0 1.0 9 P67809,O60506 2 +Negative regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay 0.4912836628356338 0.879850023797416 0.3789405612145748 1.0 1.0 9 P67809,O60506 2 +Labyrinthine layer development 0.4909679202224954 0.8782140778647387 0.3798275536171287 1.0 1.0 9 P62993,Q15363,P31749 3 +Positive regulation of i kappab kinase nf kappab signaling 0.4003634552084104 0.8779618639065194 0.3799644148032652 1.0 1.0 37 Q8WVQ1,P62942,P09601,Q8TB61,O43657,Q9H2U1,P29692,P19474,P32929,P98194,Q86UE4,Q5T9L3 12 +Glial cell migration 0.446539414443486 0.8775739935613688 0.3801749476114537 1.0 1.0 13 Q8WXH0,Q9NQC3,Q96G23,P30536 4 +Regulation of phosphatidylinositol 3 kinase signaling 0.4463265227536918 0.8762807360441421 0.3808774349314499 1.0 1.0 13 P49815,Q8NDZ4,Q05086 3 +Alcohol catabolic process 0.4506454625168166 0.8762432991108715 0.3808977822436259 1.0 1.0 12 Q9NX62,P30837,Q8WTV0 3 +Positive regulation of receptor mediated endocytosis 0.477916127307942 0.87561159512893 0.3812412197278263 1.0 1.0 10 P61978,P10909,P50570 3 +Neuron projection maintenance 0.6770278271166313 0.8752994455892141 0.3814109957122338 1.0 1.0 3 P78559,Q14203 2 +Gmp metabolic process 0.4200638718099018 0.8750192348718718 0.3815634399070227 1.0 1.0 17 P00813,Q14168 2 +Transport along microtubule 0.3837124170767715 0.8740178546954547 0.3821085303867726 1.0 1.0 57 Q9Y2T2,Q15154,O60313,P42858,P42704,Q8WXH0,O75381,O94901,P33176,O60333,Q8TD16,Q92572,Q00577,O43805,Q8NCM8,Q7Z4L5,P07196,A0AVF1,P23246,Q14168 20 +Microtubule based transport 0.3837124170767715 0.8740178546954547 0.3821085303867726 1.0 1.0 57 Q9Y2T2,Q15154,O60313,P42858,P42704,Q8WXH0,O75381,O94901,P33176,O60333,Q8TD16,Q92572,Q00577,O43805,Q8NCM8,Q7Z4L5,P07196,A0AVF1,P23246,Q14168 20 +Regulation of leukocyte apoptotic process 0.4276618418468955 0.8734727376812724 0.3824054595787891 1.0 1.0 16 P00813,Q9HCL2 2 +Protein k29 linked ubiquitination 0.676391293054444 0.8728916801332854 0.3827221215477245 1.0 1.0 3 Q96J02 1 +Positive regulation of cell cell adhesion 0.3993586766205233 0.8698928264847375 0.384358976070251 1.0 1.0 34 Q9H3S7,Q9NUQ9,P31749,Q9HCL2,P30825,P00813 6 +Pinocytosis 0.5010700272427606 0.869726351114833 0.3844499680762658 1.0 1.0 8 Q9Y5X3,Q9BZG1,P50570 3 +Regulation of toll like receptor signaling pathway 0.4635317099951241 0.8695419142878368 0.3845507928290044 1.0 1.0 11 Q9NPR9,Q9UMX0,Q9NQC3 3 +Regulation of muscle system process 0.3990990431772667 0.8668378236004192 0.3860308747583754 1.0 1.0 36 P05023,Q08209,Q13555,P78417,P0DP25,P16615,Q99996,P09493,P00813 9 +Long term synaptic potentiation 0.4629192120923888 0.866085016700968 0.3864435412326856 1.0 1.0 11 Q9BPZ3,Q13277,Q14168 3 +Notch signaling pathway 0.4094745596757387 0.8616308341024699 0.388890697747825 1.0 1.0 18 P57105,P31749 2 +Regulation of granulocyte chemotaxis 0.487427657915592 0.8598887718715471 0.3898503584396646 1.0 1.0 9 Q8NHP6,Q8NE86,O00429,Q07021,Q00013,P27361 6 +Negative regulation of keratinocyte proliferation 0.553740391022411 0.8596952141450526 0.3899570736080555 1.0 1.0 5 O14936,Q15648 2 +Regulation of binding 0.3056626366106446 0.8594595739127475 0.3900870143091663 1.0 1.0 102 P40855,P62942,Q9Y4G8,Q08209,P30533,P10586,O75381,P31749,Q08379,Q86X55,P09601,P48681,Q71SY5,Q96HY6,P35269,P35611,Q96D46,P16949,Q8IXJ6,P0DP25,P16615,O75844,P09429 23 +Negative regulation of amyloid fibril formation 0.5194985173406628 0.8570036104970306 0.3914428892551114 1.0 1.0 6 P10909,O15212 2 +Animal organ morphogenesis 0.3085478824171498 0.8553179234244125 0.3923751676753257 1.0 1.0 107 P62942,Q9NX62,Q9NQC3,P07942,O95470,Q9Y297,O94788,Q15363,P15311,P16435,P09493,Q8IZL8,Q96A65,Q9UID3,Q6P4Q7,Q15555,O75844,O14641,Q15418,Q92896 20 +Regulation of protein dephosphorylation 0.3958419597647564 0.8537432703659286 0.3932472532852733 1.0 1.0 29 Q86XL3,P0DP25,O43768,P42858 4 +Lipophagy 0.5523425921612983 0.8536694255000115 0.393288179379865 1.0 1.0 5 P42858 1 +Mesoderm morphogenesis 0.4862078088138 0.8535823916406938 0.3933364183537851 1.0 1.0 9 Q5T9L3,Q9Y2G5 2 +Oocyte differentiation 0.4733690976394353 0.8510709306453417 0.3947299522058607 1.0 1.0 10 Q9H6S0,Q8IXJ6,Q9Y2W6,Q8N2A8,Q9Y5A9 5 +Intraciliary transport involved in cilium assembly 0.6699008186995872 0.8484082699153487 0.3962106386122979 1.0 1.0 3 A0AVF1 1 +Membrane to membrane docking 0.6690329946869493 0.845144288401035 0.3980302833115718 1.0 1.0 3 P15311 1 +Signal peptide processing 0.5501341164253188 0.8441602474815826 0.398579864982175 1.0 1.0 5 Q8TCT9,P67812 2 +Negative regulation of defense response to virus 0.5066901425035557 0.8441431339982879 0.3985894268133902 1.0 1.0 7 Q07021,Q92890,O43657 3 +Glycosylation 0.3893962258310789 0.8439777300036204 0.3986818502486136 1.0 1.0 50 Q10472,Q2TAA5,O60476,Q9HC07,Q9BT22,Q08379,O60502,Q9Y2G5,Q9H9S5,P33908,Q86YN1,O15294 12 +Regulation of calcium ion transport 0.3963201747034674 0.8438402217243607 0.398758696108467 1.0 1.0 35 P30536,P78417,P0DP25,P42858,Q9UMX0,P21796 6 +Diencephalon development 0.471909151765519 0.8432038999246855 0.3991144176786607 1.0 1.0 10 O94788,O14949 2 +Regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator 0.5163686125207038 0.8426217622963244 0.3994400160126794 1.0 1.0 6 P61978 1 +Gmp biosynthetic process 0.4446857008672594 0.841033443466163 0.4003291990953403 1.0 1.0 12 P00813 1 +Transepithelial transport 0.5493657847181767 0.8408553365885832 0.4004289821842697 1.0 1.0 5 O43865 1 +Positive regulation of meiotic cell cycle 0.8014205386208968 0.8401441609753157 0.4008275621406123 1.0 1.0 2 Q8IXJ6 1 +Oligodendrocyte development 0.4578986449800978 0.8377893808299932 0.4021490038229065 1.0 1.0 11 Q96P11 1 +Negative regulation of neuron apoptotic process 0.3932818534458882 0.8374822459476355 0.4023215523952363 1.0 1.0 28 P07196,P09601,O75312,P48681,Q01105,P51858,Q15058,Q15233 8 +Protein peptidyl prolyl isomerization 0.3917225859199504 0.835342738461546 0.403524760388295 1.0 1.0 26 P62942,Q9Y237,Q96AY3,O95302,Q9Y680,Q9NWM8,Q5T1M5 7 +Regulation of systemic arterial blood pressure 0.5044376510111502 0.8334129634368566 0.4046118660733122 1.0 1.0 7 P09493 1 +Maintenance of location 0.3355884625729381 0.8333808918028734 0.4046299478639685 1.0 1.0 77 Q9H6V9,P62942,Q7L5D6,P42858,Q8NEW0,Q9HD26,P24390,P52789,O95202,P30536,P31749,Q13438,P78417,Q9H4A6,Q8WTV0,O43731,Q9UN86,Q99996,O60826,P0DP25 20 +Embryonic morphogenesis 0.3134085912405139 0.8329320402429259 0.4048830583325091 1.0 1.0 84 P67809,Q92990,Q9NX62,O94788,O15031,Q9Y2G5,O60313,Q15363,O14641,Q8N3R9,Q8NCM8,P07942,P49815,Q8IZL8,Q5T9L3 15 +Cell motility involved in cerebral cortex radial glia guided migration 0.7993489197987593 0.8325668144110389 0.4050890815195795 1.0 1.0 2 Q8WXH0 1 +Cell proliferation in forebrain 0.5473899257485473 0.8323645028620226 0.4052032320410816 1.0 1.0 5 Q15058 1 +Xenobiotic metabolic process 0.4566865123010394 0.8309693053810177 0.4059909695708499 1.0 1.0 11 O43169,P78417,P07099,P16435 4 +Regulation of cardiac muscle contraction 0.4278836845634302 0.8302776191500458 0.4063818389370928 1.0 1.0 15 P16615,P78417,P0DP25 3 +Positive regulation of ire1 mediated unfolded protein response 0.6648904677323855 0.8295965246248779 0.4067669423756148 1.0 1.0 3 Q07812,P57088 2 +Positive regulation of endoplasmic reticulum unfolded protein response 0.6648904677323855 0.8295965246248779 0.4067669423756148 1.0 1.0 3 Q07812,P57088 2 +Sensory perception of light stimulus 0.4048418400150093 0.8287003309890861 0.4072739984410707 1.0 1.0 18 O95677,Q9BV73,Q6P4Q7,O60313,Q9H6K4 5 +Cop9 signalosome assembly 0.7978691920686618 0.8271641971472911 0.4081440015159485 1.0 1.0 2 Q99627 1 +Regulation of mitophagy 0.5030124444308397 0.8266317018189074 0.408445843201153 1.0 1.0 7 P21796 1 +Cell projection assembly 0.3134078374812922 0.8265377499292481 0.408499113041924 1.0 1.0 118 Q9Y4G8,Q9UBB4,Q9BV73,Q14141,Q15154,P50570,P51116,P42858,Q8WXH0,Q9H3S7,Q15019,Q9NR77,O95721,Q9H4A6,Q16625,P15311,Q8WXW3,O95429,Q9Y3P9,Q7L576,Q9H6U6,A6NIH7,Q9H223,P53365,Q14203,Q66GS9,P25054,Q9P2S5,Q4KMQ2,Q96C92,Q8NCM8,P35609,Q9BPX3,Q96A65,Q15555,A0AVF1,Q9Y5K8,O15144 38 +Positive regulation of histone phosphorylation 0.6640023682652445 0.8262705108870897 0.408650657691755 1.0 1.0 3 Q06787,P27361 2 +Pyrimidine nucleoside triphosphate metabolic process 0.4271988871908163 0.8258869200725315 0.4088682410472319 1.0 1.0 15 Q9H773,Q9NRF8,Q13232 3 +Carbohydrate transport 0.3870467620958847 0.8257112181752448 0.4089679270615267 1.0 1.0 22 O75298,P52789,P31749,P31751,Q6ZWJ1 5 +Receptor clustering 0.4329401810378003 0.8252576805391381 0.4092253124719476 1.0 1.0 14 O43805,P57105 2 +Response to ketone 0.3931654287198266 0.8239080291339882 0.4099918179157931 1.0 1.0 41 P07196,P30536,P31749,Q13126,Q05086,P0DP25,Q9H4A6,O95831 8 +Regulation of myosin light chain phosphatase activity 0.6626457638905465 0.8211949369132967 0.4115352400286385 1.0 1.0 3 O75116 1 +Organic acid transport 0.3846954020289492 0.8198210811051356 0.4123181114341139 1.0 1.0 52 P55011,O43772,Q9H2D1,O95563,P31751,P31749,Q96QD8,P30825,Q9UBX3,Q6P4A7,P14174 11 +Regulation of nitric oxide synthase activity 0.5014649536516325 0.819275851838883 0.4126290468352045 1.0 1.0 7 Q8WTV0,P0DP25,P31749 3 +Positive regulation of jnk cascade 0.5111565671434329 0.8187369336123658 0.4129365196738637 1.0 1.0 6 Q9H2K8 1 +Muscle adaptation 0.4260568859146429 0.8185688182239864 0.4130324635081344 1.0 1.0 15 P09601,Q08209,Q13555,P16615,O75116 5 +Cell death in response to oxidative stress 0.3886649785633214 0.8172129475074164 0.4138067446159552 1.0 1.0 25 O43464,Q99720,P31749,Q9NR28,P23246,Q9UMX0,Q15233 7 +Negative regulation of protein targeting to mitochondrion 0.7949097366084664 0.8163838916824269 0.4142806066925577 1.0 1.0 2 P49257 1 +Arf protein signal transduction 0.6610420367081163 0.8152027444261161 0.4149562672089815 1.0 1.0 3 Q15555,Q92538 2 +Sodium ion transport 0.3919386817124336 0.8151997581359495 0.4149579763039588 1.0 1.0 31 P55011,P05023,P31749,Q96QD8,Q6P4Q7,O43865,Q9Y6M7,Q4KMQ2,O43707,Q14BN4 10 +Regulation of polysaccharide metabolic process 0.4900282770611406 0.8150096484407595 0.4150667872631115 1.0 1.0 8 P31751 1 +Negative regulation of interferon gamma production 0.7943178455164275 0.814231881142202 0.415512124807341 1.0 1.0 2 P09429 1 +Negative regulation of interleukin 12 production 0.7943178455164275 0.814231881142202 0.415512124807341 1.0 1.0 2 Q8WXW3 1 +T cell activation 0.3687565098356388 0.807426893072076 0.4194205781136162 1.0 1.0 62 P62942,Q9NUQ9,Q92990,Q08209,P31749,Q9HCL2,O96005,P35579,P09429,P30825,P00813,P24390 12 +Negative regulation of microtubule polymerization 0.5806131055250062 0.8074179970161313 0.4194257016821279 1.0 1.0 4 Q02790,P16949 2 +Long chain fatty acid transport 0.4243021410527571 0.8073343829896901 0.4194738598991128 1.0 1.0 15 O43772,P31749,P31751 3 +Regulation of autophagy of mitochondrion in response to mitochondrial depolarization 0.5082806206420034 0.8055945101697269 0.4204766920721976 1.0 1.0 6 O43464,P52789 2 +Axon development 0.3078802542791073 0.8041440216480766 0.4213138033742698 1.0 1.0 85 Q7L576,P07196,Q96G23,P30536,O75312,Q9UNW9,Q9UQB8,P16949,Q9Y4W6,Q9NQC3,P33176,Q13439,O15031,P00374,P16220,O00264,Q8N0X7,P10586 18 +Leukocyte tethering or rolling 0.5796877020891363 0.8037078304194346 0.4215657307721301 1.0 1.0 4 P35612,Q9H4A6 2 +In utero embryonic development 0.2953145808555599 0.8019337417925193 0.4225912867006789 1.0 1.0 92 Q9NQC3,Q96EK5,Q9NZN8,O43772,Q8TCT9,P31749,O75312,Q96AY3,Q13503,Q15363,Q15293,Q9BRT9,P00813,Q15648,P67809,Q13895,P61201,Q08J23,P31350,P35579,Q9H0W8 21 +Negative regulation of immune system process 0.3838584254881715 0.8019081241881727 0.4226061062890003 1.0 1.0 51 Q5JRA6,P28070,Q9Y4E8,P09601,Q92990,P31749,Q9HCL2,Q9Y3Z3,Q8WXW3,P15311,P09429,P00813,P14174 13 +Negative regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway 0.5400161387578762 0.8007866641214014 0.4232551607003165 1.0 1.0 5 Q07021,O43657 2 +Mesenchymal cell proliferation 0.5789161978086962 0.8006169315029511 0.4233534456911967 1.0 1.0 4 P02545,P35222,O95747 3 +Regulation of postsynaptic membrane neurotransmitter receptor levels 0.4511961187789856 0.8001394961462507 0.4236299799661913 1.0 1.0 11 Q96RT1,Q4V328,Q96QK1,Q13277 4 +Regulation of amyloid fibril formation 0.4973158201400137 0.7995923634274624 0.4239470134176333 1.0 1.0 7 P10909,O15212 2 +Positive regulation of protein localization to cilium 0.7898786623261345 0.7981358962320579 0.4247916324865202 1.0 1.0 2 Q96C92 1 +Positive regulation of nuclear division 0.4634838716397312 0.7979369990856364 0.4249070510726955 1.0 1.0 10 Q8IXJ6 1 +Positive regulation by symbiont of entry into host 0.7892867712340953 0.7959957443596404 0.4260345089374933 1.0 1.0 2 P19474 1 +Regulation of dna methylation 0.4500595736435846 0.7937710979983319 0.4273287011275524 1.0 1.0 11 Q03164 1 +Regulation of bone mineralization 0.4852546779772874 0.7914753049083525 0.4286666813133371 1.0 1.0 8 O75844,Q4KMQ2,P22413,P20248 4 +Response to peptide 0.3054177584574113 0.790999230615801 0.4289444404590168 1.0 1.0 109 Q16836,P31751,Q9H1E3,Q8TBX8,Q86YS7,Q9Y266,Q5VZ89,P11802,Q9Y5X3,P31749,P35613,Q6ZWJ1,Q9UNS1,Q9UNH7,Q92572,Q7L576,P43490,O15294,P49841,Q9UQB8,O43865,P25054,P08670,O00159,P16435,O75116,P16220,P49815,P62993,Q96RT1,P35609,P07196,P49770,O60763,Q9BSK2,O75150 36 +Glucose import 0.4272780715272899 0.7900965808691749 0.4294713665214282 1.0 1.0 14 O75298,P52789,P31749,P31751 4 +Stress granule assembly 0.4150064750383409 0.7896910404803431 0.429708225041189 1.0 1.0 16 Q14011,Q9UN86,P05198,P31483,Q7Z739,Q14157 6 +Positive regulation of hydrolase activity 0.3000683890601158 0.7865538484071126 0.4315430849854191 1.0 1.0 101 P31751,Q9Y4G8,O14737,Q14997,P61289,P31749,Q96A26,Q9Y3P9,Q9H6U6,Q06323,O43464,Q9P2J5,Q9NR28,Q9UL46,O75116,P49815,O95831,Q96HY6,Q15555,P0DP25,P07602,O14641,P09429,Q9BXK5 24 +Positive regulation of transmembrane transport 0.3894432442429765 0.7864877526577372 0.4315817914102002 1.0 1.0 38 P35609,P31749,P31751,P78417,P0DP25,Q4KMQ2,Q99996,O43707,P50570,P42858 10 +Axoneme assembly 0.6531852412663035 0.785976277702274 0.4318813850054108 1.0 1.0 3 Q15555 1 +Nuclear transcribed mrna catabolic process exonucleolytic 3 5 0.4728781061685169 0.7849746619989642 0.4324684247073802 1.0 1.0 9 Q6PGP7,Q13868 2 +Positive regulation of cellular protein catabolic process 0.3803520142125919 0.7789737557339629 0.4359951745936588 1.0 1.0 52 Q9UBS8,P10909,Q9Y4X5,P31749,P49841,Q8IXJ6,P46379,Q96JB5,Q9Y5A7,P15311,O60826,Q9UMX0,Q96QK1,Q9BW61,O75150,Q96HY6 16 +Branching involved in labyrinthine layer morphogenesis 0.7842556969517636 0.7778629842583404 0.4366497921120555 1.0 1.0 2 Q15363 1 +Tetrahydrobiopterin metabolic process 0.6509587717113845 0.7777349516645803 0.4367252826935504 1.0 1.0 3 P00374 1 +Regulation of neurogenesis 0.3581213862650529 0.777325328010745 0.4369668555005923 1.0 1.0 66 P55209,P07196,Q96G23,Q08209,Q9Y4G8,P30536,Q9UQB8,Q8IXJ6,Q9NQC3,Q13439,Q7L576 11 +Neurotransmitter secretion 0.3797190653885725 0.7773150674971153 0.4369729075575199 1.0 1.0 21 Q4J6C6,P16615,O95721,P0DP25 4 +Positive regulation of hemopoiesis 0.4194834010534327 0.7765519740853774 0.4374231455164317 1.0 1.0 15 P12956,P00813,P16220 3 +Spermidine metabolic process 0.5728582469393771 0.7764203445265762 0.4375008361631982 1.0 1.0 4 Q96QD8,P19623 2 +Polyamine metabolic process 0.5728582469393771 0.7764203445265762 0.4375008361631982 1.0 1.0 4 Q96QD8,P19623 2 +Regulation of neuron differentiation 0.3782975604003308 0.7751627111518054 0.4382435191844485 1.0 1.0 20 P49841,O60271,Q8WUJ1,Q96JB5,Q15648 5 +Positive regulation of vascular permeability 0.6493861363684217 0.7719251572196008 0.4401587563254225 1.0 1.0 3 Q16625 1 +Regulation of blood brain barrier permeability 0.6493861363684217 0.7719251572196008 0.4401587563254225 1.0 1.0 3 Q16625 1 +Positive regulation of blood brain barrier permeability 0.6493861363684217 0.7719251572196008 0.4401587563254225 1.0 1.0 3 Q16625 1 +Interleukin 1 mediated signaling pathway 0.6489046773238549 0.7701484080385057 0.4412118636238036 1.0 1.0 3 Q86Y07,P27361 2 +Response to ischemia 0.4577572536743146 0.7673163620858813 0.4428934425223829 1.0 1.0 10 Q13501,O95831,P52789 3 +Response to amine 0.4902642495861782 0.7662810315986676 0.4435091022829895 1.0 1.0 7 P0DP25,Q08209 2 +Motor learning 0.7810002959455487 0.7661873099311478 0.4435648580389553 1.0 1.0 2 Q05086 1 +Response to vitamin d 0.4991560933299327 0.7640902330686722 0.4448134722514862 1.0 1.0 6 Q8TB36,Q14258,Q15648 3 +Regulation of rna splicing 0.293349650809215 0.7633672592954879 0.4452444001494151 1.0 1.0 93 Q9UNW9,P22626,Q96QD8,P62995,P31943,P98179,Q07666,P31483,P51116,Q9HCG8,Q06787,P31942,O75312,Q9UKA9,P38159,Q07021,Q07955,P55795,Q9UHX1,P98175,Q14011,O43251,Q5BKZ1,P61978,Q96PU8,P84103,O75525,P35637,Q15287,P52597,Q8IY67 31 +Regulation of chromatin binding 0.498974897769156 0.7632692187877377 0.4453028554294362 1.0 1.0 6 Q71SY5 1 +Positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway 0.646009237071989 0.7594824269645069 0.4475640223134203 1.0 1.0 3 O43464 1 +Nuclear pore organization 0.4267767384093238 0.7581661788975562 0.4483515055237201 1.0 1.0 13 Q9BTX1,Q9NQC3 2 +Male meiotic nuclear division 0.6456483126110202 0.7581552201963914 0.448358065182536 1.0 1.0 3 Q9Y2W6,Q15645 2 +Regulation of neurotransmitter transport 0.4102077600054302 0.7581084189350047 0.4483860800927102 1.0 1.0 16 Q4J6C6,P0DP25 2 +Regulation of camp mediated signaling 0.778336786031373 0.7566690433635244 0.4492481655749876 1.0 1.0 2 Q9Y4G8 1 +Positive regulation of cytoplasmic translation 0.4432340601771689 0.7556349853740564 0.4498680740399687 1.0 1.0 11 P67809,Q9H074,O60506 3 +Heart morphogenesis 0.3852217029993458 0.755207721503981 0.4501243563777084 1.0 1.0 33 P62942,O94788,Q9NQC3,O75844,O14641,P09493 6 +Chromosome attachment to the nuclear envelope 0.7777448949393339 0.7545581761227897 0.4505141265295846 1.0 1.0 2 O94901 1 +Regulation of cardiac muscle adaptation 0.7777448949393339 0.7545581761227897 0.4505141265295846 1.0 1.0 2 Q08209 1 +Ventricular cardiac muscle cell development 0.7777448949393337 0.7545581761227883 0.4505141265295855 1.0 1.0 2 P06493 1 +Ventricular cardiac muscle cell differentiation 0.7777448949393337 0.7545581761227883 0.4505141265295855 1.0 1.0 2 P06493 1 +Appendage development 0.3943245433789143 0.7543218381052947 0.4506559923723832 1.0 1.0 18 Q9NX62,O94788,Q8NCM8,Q15648 4 +Mesoderm development 0.4211857560867197 0.7524201542433433 0.4517984301607174 1.0 1.0 14 Q5T9L3,Q96PZ0,Q96A65,Q9Y2G5 4 +Regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay 0.4294707887228273 0.7516978808731162 0.452232765084958 1.0 1.0 12 P67809,O60506,Q9H2U1,Q9H074,Q9UIV1 5 +Positive regulation of synaptic transmission 0.3750356879405447 0.75026632738401 0.45309431848532 1.0 1.0 20 Q14168,Q9BPZ3,Q13277,P33176 4 +Protein o linked glycosylation via threonine 0.7762651672092362 0.7492879465278673 0.4536836711582386 1.0 1.0 2 Q10472 1 +Protein deglycosylation 0.4864752757234497 0.7484624958823973 0.454181238576024 1.0 1.0 7 P33908,O60502 2 +Negative regulation of membrane potential 0.6429840142095956 0.7483743044239789 0.4542344170511385 1.0 1.0 3 Q07812,Q9Y255 2 +Positive regulation of autophagy 0.3831532876175649 0.7478533671748431 0.4545486080501537 1.0 1.0 30 P09601,Q8TBX8,P09429,P19474,P42858,P49815,P21796 7 +Regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway 0.4537081139916813 0.7457474848785597 0.455819968630242 1.0 1.0 10 Q9Y4E8,O43657,Q9NUD5 3 +Ribonucleoside triphosphate biosynthetic process 0.3827910843471053 0.7449507618110116 0.4563014863961687 1.0 1.0 30 P00846,O75964,P00403,P06576,Q9NRF8,P24539,Q13232 7 +Nervous system process 0.305277373597862 0.7435855787463668 0.4571272304555132 1.0 1.0 114 Q08209,Q9Y5J7,Q9BV73,Q9Y5J9,O60313,P42858,Q96P11,P31749,P78417,Q7L576,Q9H6K4,Q9UQB8,Q05086,O43251,Q99996,P16220,Q8IZL8,Q9BPZ3,P07196,O95677,Q7Z406,Q6P4Q7,O75844,Q14168 24 +Tissue regeneration 0.4943951110192066 0.7425621529267193 0.4577468094263723 1.0 1.0 6 Q7Z4V5 1 +Positive regulation of nitric oxide metabolic process 0.4943014754878505 0.7421397030745266 0.4580026966822088 1.0 1.0 6 P10909 1 +Regulation of b cell proliferation 0.4850539370752326 0.7417938784283787 0.4582122300770779 1.0 1.0 7 P00813 1 +Regulated exocytosis 0.3837647215994288 0.7387804770353215 0.4600403085405991 1.0 1.0 36 Q99584,P09601,Q4J6C6,O43760,O95721,Q13277,P0DP25,P16615,Q9UNH7,P35579,Q9BRK5,P49755 12 +Interferon gamma production 0.4842416781087454 0.7379868759647416 0.460522424330662 1.0 1.0 7 Q9NUQ9,P09429 2 +P38mapk cascade 0.5629875467325285 0.7372954084666703 0.4609427238333849 1.0 1.0 4 P15311 1 +Regulation of peptidase activity 0.2961408546937238 0.7371477755500505 0.4610324883454586 1.0 1.0 87 O14737,P61289,P31749,Q96A26,Q15392,Q06323,O43464,P61201,Q9NR28,Q9UL46,P16435,O95831,P49755,Q96HY6,P78318,P09429,Q15418,Q96K76,Q9BXK5 19 +Regulation of lipid catabolic process 0.4266911191012 0.7354831768610107 0.4620452819127965 1.0 1.0 12 P31749,P31751 2 +Response to arsenite ion 0.6394394396887992 0.735407478631956 0.4620913685709951 1.0 1.0 3 Q96QD8 1 +Muscle tissue development 0.3681741152074687 0.7352391904032567 0.4621938351410988 1.0 1.0 58 P35609,Q9BYT8,P62942,Q08209,Q7Z406,Q8IXJ6,O94788,P61201,Q9BRT2,Q8NDZ4,O75844,P50402,P09493,P60660,P16220,Q15648 16 +Export across plasma membrane 0.4514600915507832 0.7338047236527728 0.4630677612354832 1.0 1.0 10 Q12959,P05023,P05026,P20020,P0DP25,Q4KMQ2 6 +Formation of translation preinitiation complex 0.4626380152290457 0.7327234117637623 0.4637271417786548 1.0 1.0 9 P23588,P55010,Q7Z478,P41214 4 +Muscle contraction 0.3778827847862296 0.7296754004334111 0.4655886211575821 1.0 1.0 49 P35609,P06753,P05023,O75116,Q7Z406,P78417,P0DP25,P16615,P50402,Q99996,P09493,Q14BN4,P67936,P00813 14 +Positive regulation of organelle assembly 0.3812073032371109 0.7284869601205182 0.4663155481148655 1.0 1.0 31 Q66GS9,Q15555,Q9UN86,Q8TBX8,Q9P2S5,Q9P2W9,Q96C92,P42858,Q9NZN8 9 +Forebrain development 0.349331878632374 0.7278310869522004 0.4667169922111041 1.0 1.0 68 Q9Y4G8,Q96QD8,Q9NQC3,Q15154,O14949,P50542,P07942,Q8WXH0,Q96P11,O94901,O94788,O43464,P49841,Q8NCM8,P16220,Q7Z4L5,P07196,Q15058,Q8N3R9 19 +Positive regulation of endothelial cell proliferation 0.4214424029578728 0.7262187906516914 0.4677046543562353 1.0 1.0 13 Q9H2J4,P09429,P09601,P31749 4 +Ribonucleoside triphosphate metabolic process 0.3813446094437023 0.7201937172756488 0.4714057316617268 1.0 1.0 40 P00846,O00178,O75964,P00403,O60313,P06576,Q9NRF8,P24539,Q13232,Q8IWA4 10 +Triglyceride biosynthetic process 0.4804269484901484 0.7201471703206123 0.4714343872220545 1.0 1.0 7 Q9HCL2 1 +Negative regulation of protein tyrosine kinase activity 0.4800662735655887 0.7184639407109203 0.472471273940922 1.0 1.0 7 O95684,Q9BRG1 2 +Amino acid transport 0.3720088769401907 0.7183098319039573 0.4725662692658705 1.0 1.0 21 Q96QD8,Q6P4A7,P30825 3 +Trabecula morphogenesis 0.5577056543385861 0.7165263677587486 0.4736663920990058 1.0 1.0 4 P62942 1 +Protein containing complex localization 0.3770967067594088 0.7154326674425359 0.4743417327959269 1.0 1.0 48 P57105,Q15154,Q96GA3,P33176,Q13277,P15311,Q99567,Q9BTX1,Q00577,O43805,Q99996,Q8NCM8,Q7Z4L5,Q96D46,Q9NQX3,Q4V328,A0AVF1,P23246,Q96QK1,Q14168 20 +Binding of sperm to zona pellucida 0.4356586633631577 0.7135563824083234 0.4755015369274609 1.0 1.0 11 P50991,P78371,P49368,P45880 4 +Sperm egg recognition 0.4356586633631577 0.7135563824083234 0.4755015369274609 1.0 1.0 11 P50991,P78371,P49368,P45880 4 +Signal release 0.3578603874321108 0.713300837330071 0.4756596194641795 1.0 1.0 63 Q16836,Q7Z7E8,O95563,Q9H3S7,Q08209,Q4J6C6,P14174,O95721,Q6ZWJ1,Q13277,O43768,Q13555,P0DP25,Q9UNH7,P16615,P16220,Q5T9L3,Q9BRT2 18 +Nuclear transcribed mrna catabolic process deadenylation dependent decay 0.3788231151322542 0.7132173283005987 0.4757112851658642 1.0 1.0 30 P67809,Q5PRF9,O60506,Q9H074,Q13868,Q969T7,Q9NZN8 7 +Cytoplasmic pattern recognition receptor signaling pathway 0.3963353267547831 0.7131819229905716 0.475733190794168 1.0 1.0 17 Q96RT1,Q9Y4E8,Q14258,Q92890,Q96J02,O43657,Q9NUD5,Q07021 8 +Sequestering of calcium ion 0.3797328912684491 0.7131194778705506 0.475771827578237 1.0 1.0 19 P78417,P0DP25,P42858 3 +Blastoderm segmentation 0.5191666263600058 0.7125918433818608 0.4760983605185922 1.0 1.0 5 Q8N2A8 1 +Regulation of cell projection organization 0.3154966159552845 0.7092053458187606 0.4781970565725295 1.0 1.0 135 Q9NZQ3,Q9Y4G8,Q08209,Q9NQC3,Q13439,Q8WWV3,P42858,Q8WXH0,P10586,P31749,Q9NR77,O15031,Q32P28,Q86X55,Q9Y3P9,Q7L576,Q96G23,Q9UQB8,Q66GS9,P25054,P08670,Q05086,Q9P2S5,Q96C92,P07196,O14641 26 +Negative regulation of cytokine production 0.3782327767554951 0.7085068518423847 0.478630558701713 1.0 1.0 30 Q96RT1,P09601,P30536,Q9BWS9,Q8WXW3,P31483,P15311,P09429 8 +Negative regulation of mitophagy 0.6318257437995569 0.7077396545213699 0.4791069470579068 1.0 1.0 3 P49815 1 +Negative regulation of phosphoprotein phosphatase activity 0.4680230713899648 0.7072782861182687 0.4793935566645826 1.0 1.0 8 P62942,Q13464,O75116,P49841 4 +Phosphatidylglycerol acyl chain remodeling 0.6315990949061916 0.7069200345655177 0.47961617291398 1.0 1.0 3 Q8NF37 1 +Protein insertion into mitochondrial inner membrane 0.4775443040119529 0.706711596644907 0.4797457214494096 1.0 1.0 7 Q9Y5J7,Q53H12,Q9Y5J9,O60220 4 +Response to molecule of bacterial origin 0.3794017582846428 0.7054368678576058 0.4805384072459058 1.0 1.0 41 Q9NUQ9,P30536,Q8IXJ6,P31749,P08670 5 +Protein localization to lysosome 0.4021600317065746 0.705434335745791 0.4805399825410017 1.0 1.0 16 Q9Y2T2,Q9NQC3 2 +Response to camp 0.4459214044286561 0.7044855451374412 0.4811304488030274 1.0 1.0 10 Q86X55,Q99996,Q9Y4G8 3 +Negative regulation of binding 0.3796892657790029 0.7043835731347431 0.4811939331210637 1.0 1.0 38 O75381,P40855,P09601,Q08209,P31749,Q08379,P30533,P48681,P16615,P10586 10 +Negative regulation of voltage gated calcium channel activity 0.763243563184377 0.7033558849579261 0.4818339915052436 1.0 1.0 2 P0DP25 1 +Mononuclear cell differentiation 0.3764117513068014 0.7029713652705603 0.4820735946742871 1.0 1.0 47 P12956,P0CG08,Q15648,O96005,P55327,P35579,P09429,O00625,P00813,P24390 10 +Positive regulation of muscle hypertrophy 0.4766322057595977 0.7024688830917891 0.4823868006456966 1.0 1.0 7 P50750,Q13464,O75116,Q08209 4 +C21 steroid hormone metabolic process 0.5540839569799643 0.7023579406432758 0.4824559679266005 1.0 1.0 4 P30536 1 +Positive regulation of epithelial cell apoptotic process 0.5539912276200523 0.7019959767529744 0.4826816724804605 1.0 1.0 4 Q4KMQ2 1 +Regulation of adaptive immune response 0.3709344672757081 0.7016307465320868 0.482909471909398 1.0 1.0 22 Q9NUQ9 1 +Regulation of mitochondrial membrane potential 0.3697619614690312 0.7012003897272882 0.4831779666664744 1.0 1.0 21 P30536,P31751 2 +Cellular response to camp 0.4851772872760188 0.7011635545617947 0.4832009514759754 1.0 1.0 6 Q99996,Q9Y4G8 2 +Skeletal muscle tissue regeneration 0.5162552065539965 0.7004251257620833 0.4836618495714266 1.0 1.0 5 Q7Z4V5 1 +Ovarian follicle development 0.4759512021041401 0.6993038367702129 0.4843621697739892 1.0 1.0 7 P49770,Q07812,Q05086 3 +Complement activation 0.5531465723536649 0.6987007887502549 0.4847390409239094 1.0 1.0 4 P10909 1 +Anterior posterior pattern specification 0.3776116698953861 0.6976983097955832 0.4853658854133855 1.0 1.0 19 Q15363,Q8N2A8,O94788,Q5T9L3 4 +Very long chain fatty acid metabolic process 0.419852731253418 0.6957629991861947 0.4865772646795814 1.0 1.0 12 Q15067 1 +Apoptotic process involved in development 0.4837093457601767 0.6946079954084768 0.4873010002377445 1.0 1.0 6 O75312,Q07812,P30154 3 +Regulation of alpha beta t cell differentiation 0.4749115400087798 0.6944764096349046 0.4873834899116671 1.0 1.0 7 P00813 1 +Transcytosis 0.4550593803762376 0.6943644043911918 0.4874537107061807 1.0 1.0 9 P30533,O60763 2 +Muscle system process 0.3502873097018088 0.6932552093355187 0.4881494064763096 1.0 1.0 66 P35609,P09601,P05023,Q08209,O75116,P06753,Q7Z406,P78417,Q13555,P0DP25,P16615,P50402,Q99996,P09493,Q14BN4,P67936,P00813 17 +Regulation of endothelial cell migration 0.3762203724218439 0.6924715564594933 0.4886412422967459 1.0 1.0 30 P57105,P09601,P31749,P06576,Q9H6U6,P42785,Q8WTV0 7 +Regulation of membrane potential 0.3521462649310186 0.6922915408403464 0.4887542613211795 1.0 1.0 65 P35609,P05023,Q08209,P31749,P30536,P31751,P33176,Q9UQB8,Q7Z406,P0DP25,P16615,O75844,Q99996,Q14BN4,Q8IWA4,Q14168 16 +Regulation of b cell apoptotic process 0.4831045293410168 0.6919101368886319 0.4889937643139799 1.0 1.0 6 P00813 1 +Exit from mitosis 0.4109395269741921 0.6894971185614358 0.490510485896078 1.0 1.0 14 O43633,Q8IXJ6 2 +Neutral lipid biosynthetic process 0.4642584317124185 0.6890676552964445 0.4907806932784186 1.0 1.0 8 Q9HCL2 1 +Regulation of transmembrane transport 0.2995410044192002 0.6890098486932611 0.4908170698328282 1.0 1.0 85 P62942,P31751,P42858,Q9HD26,P52789,P0CG08,P31749,Q6ZWJ1,P78417,O43707,Q14BN4,P21796,O43865,Q99996,Q9UMX0,P35609,O75298,P0DP25,O75844 19 +Cardiac chamber morphogenesis 0.4151544352822593 0.6887596820241298 0.4909745114820156 1.0 1.0 13 P62942,P09493 2 +Cardiac chamber development 0.3679078546308526 0.687114744130918 0.4920104237035705 1.0 1.0 21 O75844,P62942,P09493 3 +Nuclear membrane reassembly 0.4052923775328166 0.6866081400819202 0.4923296975066198 1.0 1.0 15 Q8IXJ6,Q86XL3 2 +Regulation of fatty acid oxidation 0.4731092419789559 0.6861210627914451 0.4926367698226364 1.0 1.0 7 P31751 1 +Calcium ion transport into cytosol 0.3986176714428647 0.6823820992084523 0.4949973718449576 1.0 1.0 16 P78417,P0DP25,P42858 3 +Prostate gland development 0.472012918977768 0.6810469317152159 0.4958417946249729 1.0 1.0 7 P07602,Q05086 2 +Negative regulation of proteasomal protein catabolic process 0.3701999072038939 0.6803735666578656 0.496267953844431 1.0 1.0 24 Q96KB5,Q8N163,P46379,P49069,O15372,Q96HY6,O15294 7 +Alpha beta t cell differentiation 0.4522187930078978 0.6800643008234393 0.4964637474279434 1.0 1.0 9 P00813 1 +Response to interferon gamma 0.3708745838741849 0.678457881377074 0.4974814203079056 1.0 1.0 25 P33176,Q6ZWJ1,O00159,O60506,P08670,Q9Y5A7,P19474,Q15648 8 +Synaptic vesicle cytoskeletal transport 0.5478895410628377 0.6782697964633415 0.4976006454227248 1.0 1.0 4 Q9Y2T2 1 +Branching involved in mammary gland duct morphogenesis 0.6235471724459388 0.6779606595857616 0.4977966371914983 1.0 1.0 3 Q9Y297 1 +Regulation of microtubule based movement 0.510786677400617 0.67768446165172 0.4979717805263204 1.0 1.0 5 Q7Z4L5 1 +Regulation of pigmentation 0.7555489789878693 0.6766142460772164 0.4986507379196592 1.0 1.0 2 Q96AX1 1 +Canonical wnt signaling pathway 0.3759331829872468 0.6758096848463186 0.4991614849378782 1.0 1.0 41 Q7Z4L5,P25054,O14641,Q96K76,Q5T9L3 5 +Negative regulation of dna binding transcription factor activity 0.3728401807801116 0.6753819468242537 0.4994331322831158 1.0 1.0 28 O75381,P09601,Q00577,Q9UN86,P19474,O60826,Q9Y297,Q96JB5 8 +Mitochondrial protein processing 0.4792255158033636 0.6746521780108287 0.4998967741464999 1.0 1.0 6 Q9Y4W6,Q10713 2 +Response to zinc ion 0.4789338583427377 0.6733577869506272 0.5007196973560664 1.0 1.0 6 P30536 1 +Intrinsic apoptotic signaling pathway 0.3079478493288022 0.6727851390632551 0.5010839934796922 1.0 1.0 82 O43464,P09601,P10909,P31749,O00429,Q96RU2,P46379,Q9NR28,O60313,P61978,Q9UMX0,O95831,Q96K76,P45880 14 +Glandular epithelial cell development 0.4691160881589482 0.667670806764246 0.504343748783203 1.0 1.0 7 P49841,P31749 2 +Ornithine transport 0.7522935779816546 0.6653957718343937 0.5057973885870974 1.0 1.0 2 P30825 1 +Head development 0.3313686474062658 0.6652272837399085 0.505905132154036 1.0 1.0 169 Q9Y4G8,Q08209,Q96QD8,P46379,Q9NQC3,O14949,P07942,O95470,Q8WXH0,Q9BSJ2,Q96P11,O94788,O15031,O43464,O95456,Q9UQB8,Q05086,P48681,O43251,Q8NCM8,P16220,Q8IZL8,Q96JB5,Q5T9L3,Q7Z4L5,P07196,Q8IXJ6,Q9UID3,P0DP25,O15027,O15020,Q9H0W8,Q8N3R9,Q9UPP1 34 +Atp synthesis coupled electron transport 0.3742345617387364 0.6613419988349866 0.5083930131764038 1.0 1.0 41 Q9UDW1,P00403,P56556,P03886,O14949,O96000,P13073,O43676 8 +Protein processing 0.3723180588314818 0.6611704333740249 0.5085030201373748 1.0 1.0 46 O43464,Q8TCT9,P67812,Q9Y4W6,Q5JRX3,Q15392,Q9H9S5,P35579,O75844,Q8NCM8,Q9UG56,Q92896,O15294 13 +Pyrimidine ribonucleoside triphosphate biosynthetic process 0.4483343394577137 0.6605833800215327 0.508879530361344 1.0 1.0 9 P17812,Q9NRF8,Q13232 3 +Steroid biosynthetic process 0.3727158711864604 0.6601129485827398 0.5091813498206146 1.0 1.0 45 P48449,Q16850,P05023,P30536,Q15125,Q14849,Q15800,Q15392,P53396,P16435,Q14739,Q15648 12 +Ire1 mediated unfolded protein response 0.4673631712297257 0.6595994250431277 0.5095109233282007 1.0 1.0 7 P57088,P18031,Q92905,Q07812,Q96HY6 5 +Positive regulation of lymphocyte differentiation 0.437363510995774 0.6595118874694517 0.5095671150771324 1.0 1.0 10 P00813 1 +Cellular response to insulin like growth factor stimulus 0.6175213440359453 0.6564992358955768 0.5115029590360045 1.0 1.0 3 Q9BSK2 1 +Carbohydrate transmembrane transport 0.3801768592533533 0.6553952361204074 0.5122133178778405 1.0 1.0 18 O75298,P52789,P31749,P31751 4 +Transmembrane receptor protein tyrosine kinase signaling pathway 0.2839973358717466 0.6544759494443553 0.5128052170653925 1.0 1.0 90 P31751,Q9Y4G8,Q9H1E3,Q9NQC3,Q8TBX8,O95470,Q9Y5X3,P31749,Q6ZWJ1,Q9UNH7,Q92572,Q7L576,P43490,O15294,P49841,Q9UQB8,P25054,O00159,P49815,Q96RT1,P16949,Q8IXJ6,O14964,P49069,Q9BRG1 25 +Fat soluble vitamin metabolic process 0.4569064746765151 0.6537269019509533 0.5132877681003016 1.0 1.0 8 O94788,Q8N0U8 2 +Heart valve morphogenesis 0.5048649978669142 0.6532347985140594 0.5136049194052714 1.0 1.0 5 P20248,O75116 2 +Epithelial cell differentiation involved in prostate gland development 0.6164391256423067 0.6526648791252256 0.5139723490367369 1.0 1.0 3 P07602 1 +Regulation of dna ligation 0.616341030195375 0.652317630111066 0.5141962890836744 1.0 1.0 3 P09429,P18887 2 +Protein targeting to peroxisome 0.4563198921886411 0.650920709300763 0.5150976723099148 1.0 1.0 8 O75381,P40855,P50542 3 +Positive regulation of plasma membrane bounded cell projection assembly 0.371899818846315 0.6503262664103885 0.515481493896218 1.0 1.0 32 P50570,Q66GS9,Q15555,P25054,Q9P2S5,Q16625,Q96C92,P42858,Q7L576,Q9H6U6,O15144 11 +Response to estrogen 0.4116774418190268 0.6486400820989877 0.5165710414855127 1.0 1.0 12 P09601 1 +Nucleotide binding domain leucine rich repeat containing receptor signaling pathway 0.615232223265588 0.6483961420411246 0.516728764954868 1.0 1.0 3 Q96RT1 1 +Cellular response to acid chemical 0.4038921609496702 0.646605508477592 0.5178872920048367 1.0 1.0 14 Q9UQB8,O00410,Q9P2J5 3 +Embryonic digit morphogenesis 0.4442684791427447 0.6402902405833631 0.5219839243901656 1.0 1.0 9 Q9NX62,P42892 2 +Regulation of homophilic cell adhesion 0.7448949393311662 0.6401201357277969 0.5220944992050385 1.0 1.0 2 Q9H3S7 1 +Protein import into peroxisome membrane 0.5016082710922902 0.639870886880717 0.522256542459405 1.0 1.0 5 P40855,P50542 2 +Pattern specification process 0.3718147099070392 0.6387944720264264 0.5229566449223957 1.0 1.0 39 Q7Z4L5,O94788,P25054,Q15363,O14641,Q8NCM8,Q8N2A8,Q5T9L3 8 +Triglyceride metabolic process 0.4066639495328175 0.6385777268734222 0.5230976746824951 1.0 1.0 13 Q8WTV0,Q9HCL2 2 +Positive regulation of protein serine threonine kinase activity 0.3717033030699356 0.6378630218920299 0.5235628506951064 1.0 1.0 39 P31749,Q9Y4G8,P0DP25,Q8NDZ4,O14641 5 +Positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay 0.5366300885253978 0.6349926798484101 0.5254331892129427 1.0 1.0 4 Q9UIV1,Q9H2U1 2 +Neural tube development 0.3688595298698137 0.6341417602262602 0.5259883115541246 1.0 1.0 30 O15031,O94788,O60313,Q15363,O14641,P49815 6 +Regulation of leukocyte migration 0.3689382306757571 0.6304670054999262 0.5283890833869473 1.0 1.0 31 Q5JRA6,P09601,P31749,O00429,Q4KMQ2,P09429,Q00013,P00813,P14174 9 +Cellular component assembly involved in morphogenesis 0.3646307975916956 0.630392406653862 0.528437877656504 1.0 1.0 25 P35609,Q9NR77,P09493 3 +Interleukin 2 production 0.4609781779844613 0.630352336005657 0.528464088365967 1.0 1.0 7 P15311,Q92990,Q01082 3 +Negative regulation of protein binding 0.3654988609645166 0.6302416028430936 0.5285365237477408 1.0 1.0 26 O75381,P31749,Q08379,P30533,P48681,P16615,P10586 7 +Somitogenesis 0.4519811445785774 0.6302302611421293 0.5285439431334578 1.0 1.0 8 O94788 1 +Endocytosis 0.3076566243973879 0.6296552769831849 0.5289201492530733 1.0 1.0 131 Q5T1M5,P57105,Q9NZQ3,Q08209,Q9UBG0,Q9Y2T2,P30533,Q96ED9,Q9BZG1,Q96D71,Q9NX40,Q5JRA6,Q9Y5X3,P10909,O00429,P15311,Q5VW38,Q8WTV0,Q05086,Q15075,P61978,P49815,Q15276,Q14C86,P0DP25,P35579,O15260 27 +Cellular response to salt stress 0.4989589174129648 0.6290446615420766 0.5293198176975042 1.0 1.0 5 Q9BPX6 1 +Hyperosmotic salinity response 0.4989589174129648 0.6290446615420766 0.5293198176975042 1.0 1.0 5 Q9BPX6 1 +Cellular hyperosmotic salinity response 0.4989589174129648 0.6290446615420766 0.5293198176975042 1.0 1.0 5 Q9BPX6 1 +Intestinal absorption 0.4313979429406536 0.6284274012838713 0.5297239914582907 1.0 1.0 10 Q16739 1 +Magnesium ion homeostasis 0.6092303881962351 0.6272865408546751 0.5304714242912041 1.0 1.0 3 Q6P4Q7 1 +Substantia nigra development 0.3833865558582375 0.6263708755259448 0.5310717080337684 1.0 1.0 17 Q8IXJ6,P24539,O15027,P0DP25 4 +Anoikis 0.4511516345963262 0.6262881539799389 0.5311259548561378 1.0 1.0 8 P49815,P31749 2 +Meiotic cell cycle process 0.3702909394422655 0.6260664098799295 0.531271383226612 1.0 1.0 39 Q9BTX1,Q92791,Q8IXJ6,P46379,Q9Y2W6,Q08379,P35579,Q08J23,Q9BXW9,Q9NTJ3 10 +Positive regulation of extrinsic apoptotic signaling pathway in absence of ligand 0.4980158769993396 0.6252011416136957 0.5318390527423609 1.0 1.0 5 P30154 1 +Nucleoside phosphate catabolic process 0.3675498423164632 0.6250885580241227 0.5319129371320157 1.0 1.0 19 Q9H773 1 +Negative regulation of response to wounding 0.4411890929351207 0.6249911984153474 0.5319768347863785 1.0 1.0 9 Q96G23 1 +Polyamine biosynthetic process 0.6083334216747537 0.6241490984614317 0.5325296719020807 1.0 1.0 3 Q96QD8 1 +Regulation of immune response 0.3047979134398232 0.6224780508169412 0.5336275720860391 1.0 1.0 127 P12956,Q9Y4E8,P62942,P46379,Q14166,Q9NQC3,Q5RKV6,Q07666,P28070,Q9NUQ9,P10909,P51812,Q9NZ08,Q9NUD5,Q7Z739,P15311,P19474,P23396,Q07021,Q15233,P00813,Q15648,Q9BY67,P09601,Q9Y3Z3,Q8WXF1,Q16543,Q9UMX0,Q96RT1,Q9NPR9,P49770,O43657,P26583,P43246,P23246,P09429,Q9UIV1 37 +Nerve development 0.450289179022214 0.6221942574798492 0.5338141415793358 1.0 1.0 8 Q9Y4W6,P42892 2 +Purine nucleoside monophosphate biosynthetic process 0.3997359862149969 0.6214826667732382 0.5342820955761975 1.0 1.0 14 P00813 1 +Semaphorin plexin signaling pathway involved in neuron projection guidance 0.6073373204244847 0.6206703123520044 0.5348165665115943 1.0 1.0 3 O15031 1 +Spermatid nucleus differentiation 0.4967513676125542 0.6200558921065012 0.5352209900055651 1.0 1.0 5 P26583,Q14997 2 +Nad biosynthesis via nicotinamide riboside salvage pathway 0.7386800828647563 0.6191359363774985 0.5358268110434257 1.0 1.0 2 P43490 1 +Regulation of atp metabolic process 0.3638698891190197 0.617703354137563 0.5367709005923023 1.0 1.0 26 P30536,O00429,P00403,Q9BRT2,P14406,O15294 6 +Cellular potassium ion homeostasis 0.5320572329197266 0.6176187220321672 0.536826700362955 1.0 1.0 4 P55011,P05023 2 +Potassium ion homeostasis 0.5320572329197266 0.6176187220321672 0.536826700362955 1.0 1.0 4 P55011,P05023 2 +Detection of light stimulus 0.5318884615639561 0.616979862782873 0.5372480081244726 1.0 1.0 4 Q9BV73 1 +Neurotransmitter receptor transport to plasma membrane 0.4959381422873025 0.616752091774029 0.5373982561761519 1.0 1.0 5 Q4V328,Q13277 2 +Extracellular matrix assembly 0.4660637419123776 0.6167238751770648 0.5374168705882907 1.0 1.0 6 Q96AY3 1 +Regulation of cysteine type endopeptidase activity 0.3629038846243602 0.6163580982342853 0.5376582019542089 1.0 1.0 52 O43464,P31749,P61201,Q96A26,Q9NR28,P78318,Q15392,O14737,P16435,O95831,Q96K76,Q9BXK5,Q15418 13 +Cellular copper ion homeostasis 0.5316794846956123 0.6161890487536615 0.537769755370354 1.0 1.0 4 O75880 1 +Copper ion homeostasis 0.5316794846956123 0.6161890487536615 0.537769755370354 1.0 1.0 4 O75880 1 +Response to epidermal growth factor 0.3745004216097377 0.6161756231679901 0.5377786152269297 1.0 1.0 18 P31749,Q9UQB8,O75312,P12270,Q15648 5 +Cellular response to insulin stimulus 0.355782947487018 0.6134934724368621 0.5395500975816505 1.0 1.0 58 P31751,Q9H1E3,Q8TBX8,Q86YS7,Q5VZ89,P11802,Q9Y5X3,P31749,Q6ZWJ1,Q92572,Q7L576,P43490,O15294,P49841,Q9UQB8,P25054,O00159,P49815,P62993,O60763,Q9BSK2 21 +Camp mediated signaling 0.6052437353505006 0.6133774564742313 0.539626788623202 1.0 1.0 3 Q9Y4G8 1 +Facultative heterochromatin assembly 0.3810785231888499 0.6110496246456588 0.5411667280543804 1.0 1.0 17 Q8IXJ6,Q8NEY8 2 +Embryonic organ development 0.3552277928351685 0.6080790820863657 0.5431350250150166 1.0 1.0 58 P31749,O94788,Q03164,Q8IZL8,P00813 5 +Chaperone mediated protein complex assembly 0.4013800809322586 0.6076134053080036 0.5434439078093174 1.0 1.0 13 O95456,P10909,O15212 3 +Regulation of reproductive process 0.3649541271753601 0.6065203187543287 0.5441692940092298 1.0 1.0 19 Q9H6S0,Q8IXJ6,Q7Z739,P35579,Q07021,Q9Y5A9,P00813 7 +Regulation of cytosolic calcium ion concentration 0.3594149915534482 0.6059036510006828 0.544578734898407 1.0 1.0 23 P62942,P78417,P0DP25,P42858 4 +Ventricular cardiac muscle cell membrane repolarization 0.6030815875921334 0.6058728953513185 0.544599159334753 1.0 1.0 3 O75844 1 +Regulation of sodium ion transport 0.3570916945501772 0.6056196683439391 0.5447673386420329 1.0 1.0 21 P05023,P31749,O43865,O43707,Q14BN4 5 +Negative regulation of peptide secretion 0.4552503229545396 0.6043334502518313 0.5456219713240316 1.0 1.0 7 Q16836 1 +Negative regulation of hormone secretion 0.4552503229545396 0.6043334502518313 0.5456219713240316 1.0 1.0 7 Q16836 1 +Positive regulation of cartilage development 0.7336490085824242 0.6023218242744718 0.5469599362668616 1.0 1.0 2 P16435 1 +Cellular response to gonadotropin stimulus 0.7336490085824242 0.6023218242744718 0.5469599362668616 1.0 1.0 2 P16435 1 +Response to gonadotropin 0.7336490085824242 0.6023218242744718 0.5469599362668616 1.0 1.0 2 P16435 1 +Positive regulation of low density lipoprotein receptor activity 0.6019209338062697 0.6018559490550953 0.547270028865003 1.0 1.0 3 P61978 1 +Excretion 0.4921022327503795 0.6012243938503015 0.547690539051692 1.0 1.0 5 P09601 1 +Regulation of cardiac muscle cell action potential 0.436347509232495 0.6010680921086781 0.5477946345389038 1.0 1.0 9 P16615,P0DP25 2 +Negative regulation of toll like receptor signaling pathway 0.5274102066847172 0.6000915610008908 0.5484452164200138 1.0 1.0 4 Q9UMX0 1 +Trachea formation 0.5273911755996331 0.6000200565796954 0.5484928688889661 1.0 1.0 4 P35222,P28482,P27361 3 +Trachea morphogenesis 0.5273911755996331 0.6000200565796954 0.5484928688889661 1.0 1.0 4 P35222,P28482,P27361 3 +Trachea development 0.5273911755996331 0.6000200565796954 0.5484928688889661 1.0 1.0 4 P35222,P28482,P27361 3 +Central nervous system neuron development 0.3999704652812187 0.5993907952533343 0.5489123137055163 1.0 1.0 13 Q8N3R9,O14949,Q9Y4G8 3 +Cellular response to vitamin d 0.4914424619802924 0.598563162005598 0.5494642275952963 1.0 1.0 5 Q15648 1 +Microtubule based movement 0.2990770543800892 0.5964358800936727 0.5508840769168708 1.0 1.0 83 Q9Y2T2,Q2M1P5,Q15154,O60313,P42858,Q8WXH0,P42704,O75381,O94901,P33176,O60333,Q8TD16,Q92572,Q00577,O43805,Q8NCM8,Q86UP2,Q7Z4L5,P07196,A0AVF1,P78318,P23246,Q15058,Q14168 24 +Mitochondrial protein catabolic process 0.7312814442142681 0.5944646562431976 0.5522013748598091 1.0 1.0 2 Q9UG56 1 +Atp metabolic process 0.2949557324347208 0.5934938373176667 0.5528507060646595 1.0 1.0 114 P00846,Q9BRR6,P30536,O75964,Q9UDW1,O00429,P22695,P00403,P56556,P03886,O14949,P06576,O96000,P13073,O43676,P14406,O15294 17 +Positive regulation of protein dephosphorylation 0.3948447147677584 0.5920991011317925 0.5537842288116641 1.0 1.0 14 Q86XL3 1 +Protein localization to cytoskeleton 0.3574509122734698 0.5910982623503428 0.5544545840839279 1.0 1.0 23 Q13561,P49841,Q9BV73,Q15555,P25054,Q15154,Q9P2S5,Q8WXW3 8 +Dna replication checkpoint signaling 0.4600645899745076 0.5906779876289318 0.5547361996360554 1.0 1.0 6 O75419,Q9UNS1 2 +Trna transport 0.4888581724564856 0.5881668534755907 0.556420303491806 1.0 1.0 5 P67809 1 +Regulation of dna binding 0.3599858807500968 0.5879334203263492 0.5565769830832923 1.0 1.0 26 Q8IXJ6,P09601,Q96HY6,P0DP25 4 +Vesicle organization 0.2883298919765696 0.5872755778543284 0.5570186405459696 1.0 1.0 104 O43633,Q9H4A5,P31751,Q9BVK6,Q96ED9,Q9BZG1,Q13190,Q5JRA6,O95249,Q9NR31,O43752,O95721,Q13277,Q9H4A6,Q15363,Q13501,Q15075,P16220,Q15437,P49755,O14964,O60763,Q8WUX9,O15027,Q9BRG1 25 +Positive regulation of sodium ion transport 0.4006650370245608 0.5859094654397962 0.5579363561421606 1.0 1.0 12 O43865,O43707,P31749 3 +Fatty acid transport 0.3698393633407738 0.5842159035160008 0.5590750630810959 1.0 1.0 18 O43772,P14174,P31749,P31751 4 +Cellular response to peptide hormone stimulus 0.3294577012748092 0.5802364508109267 0.56175517578963 1.0 1.0 71 P31751,Q9H1E3,Q8TBX8,Q86YS7,Q5VZ89,P11802,Q9Y5X3,P31749,Q6ZWJ1,Q92572,Q7L576,P43490,O15294,P49841,Q9UQB8,O43865,P25054,O00159,P16435,O75116,P49815,P62993,P35609,O60763,Q9BSK2 25 +Insulin like growth factor receptor signaling pathway 0.4866804884878152 0.5794411184233749 0.5622915661855838 1.0 1.0 5 P31749 1 +Negative regulation of epithelial cell migration 0.4110069477588007 0.578996495234633 0.5625915380201214 1.0 1.0 11 Q9H3S7,P57105 2 +Negative regulation of mrna processing 0.3557582230238384 0.5783773000221527 0.5630094162042196 1.0 1.0 23 Q5VTR2,P22626,P98175,P38159,P61978,Q15287,Q07021,O75150 8 +Vesicle fusion with golgi apparatus 0.5949040677697347 0.577747911752724 0.5634343268046864 1.0 1.0 3 Q13190 1 +Negative regulation of rna catabolic process 0.3622489783541791 0.5776935743466424 0.5634710181493379 1.0 1.0 31 P67809,Q92804,P98175,Q14011,O60506,Q9H2U1,Q99729,Q9H074,P35637,P42704 10 +Protein maturation 0.3354104827843034 0.5761520802940383 0.5645123918599033 1.0 1.0 68 O43464,P62942,Q8TCT9,P67812,Q9Y4W6,Q9BU89,Q86UY6,Q5JRX3,Q15392,Q9H9S5,Q9BXJ9,P35579,Q8NCM8,O00170,O75844,Q9UG56,Q92896,O15294 18 +Extrinsic apoptotic signaling pathway via death domain receptors 0.3815034980863326 0.5724473077485192 0.567018973830635 1.0 1.0 16 P09601 1 +Positive regulation of nuclease activity 0.4846700843545944 0.5714146619753017 0.5677185926138699 1.0 1.0 5 P26583,P31749 2 +Blood vessel morphogenesis 0.2776008925984902 0.5704215419638569 0.5683918221895079 1.0 1.0 89 P55011,P57105,Q9Y4G8,Q9H2J4,O95470,Q5JRA6,P52789,P31749,Q96AY3,Q9NZ08,P06576,Q9H6U6,Q86UE4,Q15648,P09601,Q92990,Q9BXJ9,O75116,Q96PU8,P35579,P42785 21 +Negative regulation of cell aging 0.484128272209786 0.5692563460143745 0.5691821872550065 1.0 1.0 5 P67809 1 +Establishment or maintenance of transmembrane electrochemical gradient 0.7235868600177604 0.5691822934638412 0.569232435635314 1.0 1.0 2 Q07812 1 +Response to salt stress 0.4379934891759937 0.5643965251560674 0.5724843031794298 1.0 1.0 8 O95202,Q9BPX6 2 +Regulation of t cell activation 0.3623932125775807 0.5613810136007283 0.574537824405825 1.0 1.0 41 Q9NUQ9,Q9HCL2,P31749,O96005,P00813 5 +Response to muscle activity 0.5169320868676839 0.5610796570439863 0.5747432354443616 1.0 1.0 4 Q9UDX5 1 +Actin filament based movement 0.3598305116427169 0.5587528779532489 0.5763303860330287 1.0 1.0 31 P05023,Q7Z406,O00159,P35580,P60660,P16615,P35579,Q99996,O43707,P09493,Q8WXH0 11 +Protein o linked fucosylation 0.7203314590115457 0.5586061871365009 0.5764305165316084 1.0 1.0 2 Q9Y2G5 1 +Fucosylation 0.7203314590115457 0.5586061871365009 0.5764305165316084 1.0 1.0 2 Q9Y2G5 1 +Digestive system process 0.3928763637541583 0.5582739412948368 0.5766573364005005 1.0 1.0 13 Q16739 1 +Positive regulation of b cell activation 0.3954523858588321 0.556564150681595 0.577825253005001 1.0 1.0 12 Q5RKV6,P00813 2 +Negative regulation of axonogenesis 0.4518589241779551 0.5554602792302781 0.5785798717149302 1.0 1.0 6 Q9NQC3 1 +Positive regulation of autophagy of mitochondrion 0.4516914078948353 0.5547465271470308 0.5790680469444351 1.0 1.0 6 P21796 1 +Regulation of oxidative stress induced intrinsic apoptotic signaling pathway 0.3885123353600762 0.5543824136846652 0.5793171591192956 1.0 1.0 14 O43464,P31749,P23246,Q9UMX0,Q15233 5 +Myeloid leukocyte cytokine production 0.4353516294003997 0.552127104621424 0.5808612728465874 1.0 1.0 8 P09601,P14174 2 +Intrinsic apoptotic signaling pathway by p53 class mediator 0.3486018808234677 0.5520502267107447 0.5809139418065872 1.0 1.0 20 Q96RU2,P46379,P61978 3 +Positive regulation of t cell proliferation 0.3945857901484831 0.551709491216081 0.581147406172148 1.0 1.0 12 P30825,Q9HCL2 2 +Endoplasmic reticulum calcium ion homeostasis 0.4256054516729234 0.5486182940049478 0.583267428622029 1.0 1.0 9 P16615 1 +Positive regulation of dephosphorylation 0.3825760472883684 0.5457196772581993 0.5852586437948619 1.0 1.0 15 Q86XL3 1 +Protein destabilization 0.4047039871706499 0.5453293239933942 0.5855270394692891 1.0 1.0 11 Q9Y297,P19474,P42858 3 +Negative regulation of mrna metabolic process 0.3588857452851456 0.5435563604059976 0.5867467969352509 1.0 1.0 46 P67809,Q06787,Q16629,Q92804,Q5VTR2,P22626,P98175,Q14011,O60506,P35637,Q99729,Q9H074,P38159,P61978,Q15287,Q07021,Q14103,O75150 18 +Male gamete generation 0.3143452639022259 0.5424851149094996 0.5874843589104195 1.0 1.0 76 P46379,Q07666,P50570,O95470,Q14997,P41208,Q9Y508,Q9H6S0,Q15019,O94901,Q9Y2W6,Q9BTX1,Q9H2U1,Q99417,Q08J23,Q96PU8,Q9BPZ3,Q15067,A0AVF1,P26583,O75718,Q8N2A8,Q14141 23 +Protein localization to ciliary membrane 0.4487425231379405 0.5422176375728662 0.5876685863313036 1.0 1.0 6 Q15276 1 +Negative regulation of collateral sprouting 0.7150044391831941 0.5414597798254899 0.5881907127484425 1.0 1.0 2 Q8N0X7 1 +Negative regulation of synapse organization 0.715004439183194 0.5414597798254887 0.5881907127484434 1.0 1.0 2 O00264 1 +Positive regulation of locomotion 0.2793599372359489 0.5398325103580494 0.5893125445416878 1.0 1.0 95 P31751,Q9Y4G8,Q08209,Q9NQC3,P07942,Q8WXH0,Q5JRA6,P31749,O00429,O60271,Q13277,P06576,O95429,O43707,Q07021,Q9H6U6,Q8WTV0,P09601,P25054,O00159,O95684,Q4KMQ2,O75116,Q96HY6,Q15555,P09429,Q96QK1 27 +Cellular hyperosmotic response 0.4479350087112936 0.5387987273400348 0.5900257418652584 1.0 1.0 6 O95202,Q9BPX6 2 +Centriole assembly 0.423480809011297 0.5383562650122895 0.5903311139880523 1.0 1.0 9 O43633,Q66GS9 2 +Cardiac conduction 0.3699061365731292 0.5376728330689098 0.5908029379181201 1.0 1.0 17 P16615,O75844,Q99996,P0DP25 4 +Response to osmotic stress 0.3475538376482747 0.5349091661818641 0.5927126696596021 1.0 1.0 21 P30536 1 +Ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway 0.3806550217516646 0.5340322972627295 0.5933191890258711 1.0 1.0 15 O43633,Q8WUX9,Q9H3S7,Q9BRG1 4 +Axo dendritic protein transport 0.5086246281564393 0.5306896471885648 0.5956338613645014 1.0 1.0 4 Q14168 1 +Protein localization to presynapse 0.5086246281564393 0.5306896471885648 0.5956338613645014 1.0 1.0 4 Q14168 1 +Protein transport along microtubule 0.5086246281564393 0.5306896471885648 0.5956338613645014 1.0 1.0 4 Q14168 1 +Protein polymerization 0.2879594887860817 0.5306126617972791 0.595687219635771 1.0 1.0 85 O43633,Q13813,Q96P70,Q9BSJ2,Q9NSV4,Q9NUQ9,O00429,Q08379,Q16625,O95429,Q7L576,Q01082,Q14203,Q9UQB8,P35612,Q99996,P62993,P45880,Q13045,Q9BPX3,P07196,P35611,P16949,Q9UEY8,O15020,O15144 26 +Cell communication by electrical coupling involved in cardiac conduction 0.4457278108374434 0.5294806088790894 0.596472092616209 1.0 1.0 6 P0DP25 1 +Muscle cell differentiation 0.3365993734890762 0.5293134552491288 0.5965880231734246 1.0 1.0 65 P67809,P35609,Q7Z4V5,P31749,Q9Y4W6,Q08209,O60271,P16615,O75844,P35579,O43707,Q96PU8,P12814,P09493 14 +Negative regulation of extrinsic apoptotic signaling pathway 0.3501791859631221 0.5286013973422656 0.5970819907549996 1.0 1.0 24 Q07820,P09601,O95677,P31749,P49841,P02545,P26583,P42858,P61289 9 +Regulation of early endosome to late endosome transport 0.3904346941321538 0.5285555093774057 0.5971138304549037 1.0 1.0 12 P35241,P15311,Q9H3S7 3 +Dendritic transport 0.445495284500336 0.5285012730026983 0.5971514637557986 1.0 1.0 6 P23246,P33176 2 +U4 snrna 3 end processing 0.4380271667907182 0.5275179431172737 0.597833959437259 1.0 1.0 7 Q13868 1 +Nucleoside metabolic process 0.353599885360604 0.5262465159724211 0.5987169384581588 1.0 1.0 19 O60725,P00813 2 +Negative regulation of biomineralization 0.5071643263556872 0.525400206523707 0.5993050099901194 1.0 1.0 4 P22413,O75116 2 +Copii coated vesicle cargo loading 0.4207068965022684 0.5250180792958401 0.5995706228757098 1.0 1.0 9 Q15437,Q9NR31 2 +Mast cell activation involved in immune response 0.4371197973873976 0.5235365584805064 0.6006009170479651 1.0 1.0 7 Q9UNH7,P09601 2 +Regulation of epithelial cell differentiation involved in kidney development 0.5787448194197844 0.5234633055083656 0.6006518801244574 1.0 1.0 3 P35222,O95747 2 +Nephron tubule epithelial cell differentiation 0.5787448194197844 0.5234633055083656 0.6006518801244574 1.0 1.0 3 P35222,O95747 2 +Renal vesicle development 0.5787448194197844 0.5234633055083656 0.6006518801244574 1.0 1.0 3 P35222,O95747 2 +Neural retina development 0.4441481481481513 0.5228363403897727 0.6010881480984036 1.0 1.0 6 P20020,Q15555,O96019,Q8NBN7,P54802 5 +Mucopolysaccharide metabolic process 0.4200012509115237 0.5216361159691153 0.6019237122272949 1.0 1.0 9 Q8NCH0 1 +Formation of primary germ layer 0.3786020234050447 0.5215880594888842 0.6019571787645903 1.0 1.0 15 P07942,Q5T9L3,Q9Y2G5 3 +Cardiac muscle cell membrane repolarization 0.4364160369529566 0.5204534496719978 0.6027475647316649 1.0 1.0 7 O75844,Q99996 2 +Protein deneddylation 0.4197404007847702 0.5203870918569241 0.6027938050245119 1.0 1.0 9 Q99627,P61201,Q9BT78 3 +Protein localization to postsynapse 0.4358474364700005 0.5179656011736091 0.6044822699108765 1.0 1.0 7 Q4V328,Q13277 2 +Establishment of protein localization to vacuole 0.3439287376381283 0.5178849042685588 0.6045385750373122 1.0 1.0 20 Q9H3S7,P10909,Q9Y2T2,O14964,P11142,Q9BRG1,Q9H9H4 7 +Development of secondary sexual characteristics 0.5050662151052843 0.5178290460599715 0.6045775506920692 1.0 1.0 4 Q15648 1 +Negative regulation of immune response 0.3504552132214502 0.5157291463503904 0.6060435949341765 1.0 1.0 26 P28070,P09601 2 +Chemokine production 0.4090801021515392 0.5145242751027843 0.6068854929037508 1.0 1.0 10 P09429,P09601,P14174 3 +Potassium ion export across plasma membrane 0.7061260728026082 0.5133406561346266 0.6077130493029055 1.0 1.0 2 Q4KMQ2 1 +Negative regulation of p38mapk cascade 0.7061260728026082 0.5133406561346266 0.6077130493029055 1.0 1.0 2 P15311 1 +Regulation of potassium ion export across plasma membrane 0.7061260728026082 0.5133406561346266 0.6077130493029055 1.0 1.0 2 Q4KMQ2 1 +Interleukin 12 production 0.4346527044155202 0.5127474092350724 0.6081280217875253 1.0 1.0 7 Q8WXW3,P09429 2 +Ribonucleoprotein complex disassembly 0.4696350492375256 0.5123344557087628 0.608416954721243 1.0 1.0 5 Q14562,P33176 2 +Negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator 0.4691828374930262 0.5105849781829797 0.6096416967325737 1.0 1.0 5 Q8N2F6,P14174 2 +Positive regulation of neuron apoptotic process 0.3866247129597602 0.5074578030955434 0.6118336367983406 1.0 1.0 12 Q07820,Q15375,O95831,P49427,Q07812 5 +Cellular anion homeostasis 0.5737819337312073 0.5071630585356895 0.6120404127381174 1.0 1.0 3 P55011 1 +Activation of innate immune response 0.3508529684282674 0.507087278653041 0.61209358056927 1.0 1.0 19 P12956,Q8WXF1,P23246,P09429,Q15233 5 +Tube formation 0.3509128819228362 0.5001080634717463 0.6169989887047607 1.0 1.0 29 P49815,O15031,O60313,Q15363,O14641,Q9H6U6 6 +Intermediate filament based process 0.3746126256866596 0.4975490030286724 0.6188019557499609 1.0 1.0 15 P07196,P08670 2 +Neurotransmitter receptor transport 0.4380660535505898 0.4974531389929648 0.6188695407376039 1.0 1.0 6 Q4V328,Q13277 2 +Regulation of mrna export from nucleus 0.4656656979268482 0.4970365706041645 0.619163262539125 1.0 1.0 5 P12270 1 +Regulation of mitotic cell cycle spindle assembly checkpoint 0.4651889760123872 0.4952082668198745 0.6204531157970734 1.0 1.0 5 P12270,Q13257,Q5JVF3 3 +Interleukin 10 production 0.4986121921212087 0.4947565837451309 0.6207719545862935 1.0 1.0 4 Q8WXW3 1 +Regulation of endothelial cell development 0.437193722307692 0.4938392562984917 0.6214197065798976 1.0 1.0 6 P35611 1 +Dendritic spine morphogenesis 0.3689084618073238 0.4934626804857472 0.6216857028781737 1.0 1.0 16 Q9UQB8,Q05086 2 +Regulation of cytoplasmic transport 0.3780813780813677 0.4931646190103531 0.6218962752123822 1.0 1.0 14 P26038,Q9H3S7,Q9UL25,P35241,Q13614,P15311,O60493,O75165,Q9UMY4,P28482,P27361,Q93009,Q02750 13 +Detection of abiotic stimulus 0.4224241361835688 0.4929497626356894 0.6220480846036744 1.0 1.0 8 Q9BV73,Q15555 2 +Multicellular organism growth 0.3504352212070013 0.4910036716036769 0.6234238507102319 1.0 1.0 30 O43464,Q9HCL2,Q9Y4W6,Q15363,O75844,O15020,P16220,O95470 8 +Negative regulation of neuron death 0.3530142100548202 0.4898547443188532 0.6242366890061857 1.0 1.0 45 O43464,Q9UMX5,P07196,P09601,P31749,O75312,P48681,Q01105,P51858,Q15058,Q15233 11 +Negative regulation of glycogen metabolic process 0.6984314886061005 0.4894557423111744 0.6245190803808878 1.0 1.0 2 P49841 1 +Amp metabolic process 0.3682330233185744 0.4892825274874192 0.6246416893466806 1.0 1.0 16 P00813 1 +Hyperosmotic response 0.4213929202622732 0.4882953159218533 0.6253406788183045 1.0 1.0 8 P55011,Q9BPX6 2 +Ribonucleoprotein complex localization 0.4356777733053635 0.4875754590475963 0.6258505818461806 1.0 1.0 6 P12270,Q08J23 2 +Leukocyte adhesion to vascular endothelial cell 0.462802341173415 0.4860847595618269 0.6269070720253265 1.0 1.0 5 Q9H4A6 1 +Regulation of cysteine type endopeptidase activity involved in execution phase of apoptosis 0.6972477064220224 0.4858225662319297 0.6270929732153163 1.0 1.0 2 P23396 1 +Positive regulation of cellular amide metabolic process 0.3306178112957332 0.4853983356519396 0.6273938127498513 1.0 1.0 66 P98179,Q7Z478,Q07666,Q9H074,Q9BRP8,P51116,Q96P11,Q06787,P10909,O15031,Q7Z739,Q07021,P67809,Q14011,O60506,P08670,Q9H2U1,O75116,Q9BRT2,Q9Y2R0,Q567V2 21 +Positive regulation of endothelial cell migration 0.34321282135387 0.4853605043288777 0.6274206435226768 1.0 1.0 23 P09601,P31749,P06576,P09429,Q9H6U6,Q8WTV0 6 +Positive regulation of neural precursor cell proliferation 0.4279273059067003 0.4836143624848281 0.6286595798452543 1.0 1.0 7 P55209 1 +Regulation of microvillus length 0.5664586900142236 0.483452944758743 0.6287741631173966 1.0 1.0 3 P15311 1 +Synaptic vesicle transport 0.4026146938544975 0.4823678340268572 0.6295446670089617 1.0 1.0 10 P50570,Q9Y2T2,P33176 3 +Regulation of non motile cilium assembly 0.4199202133497829 0.4816662094549436 0.6300430839162916 1.0 1.0 8 Q66GS9,Q15555,Q9P2S5 3 +Regulation of skeletal muscle cell differentiation 0.4944247393707366 0.4799689076364514 0.6312495018906805 1.0 1.0 4 Q9BRT2 1 +Regulation of peptidyl lysine acetylation 0.3435840401332796 0.4798119642981757 0.6313611046828198 1.0 1.0 24 Q03164,Q01105 2 +Ether metabolic process 0.4267915882630627 0.4787365506783227 0.6321260599306173 1.0 1.0 7 O00116 1 +Reticulophagy 0.4939179437498924 0.4781892280118635 0.6325155287393533 1.0 1.0 4 Q96HY6 1 +Regulation of cyclase activity 0.4262316085427227 0.4763360844370009 0.633834961796315 1.0 1.0 7 P0DP25 1 +Regulation of canonical wnt signaling pathway 0.3517634467402015 0.4748093784152583 0.6349228477797704 1.0 1.0 38 Q7Z4L5,Q96K76,P25054,Q5T9L3 4 +Apical protein localization 0.4928909622683053 0.4745895960214409 0.6350795232789286 1.0 1.0 4 Q9HD26 1 +Polysaccharide biosynthetic process 0.3657871517781904 0.4741974293493933 0.6353591263441474 1.0 1.0 16 Q7LGA3,P31751 2 +Response to acid chemical 0.3403301642312177 0.4730869669259515 0.6361511347037576 1.0 1.0 22 Q9P2J5,Q9UQB8,O00410,Q99729,O95831 5 +Positive regulation of exosomal secretion 0.4178300265219679 0.4722947346333925 0.636716428141034 1.0 1.0 8 O43633 1 +Regulation of transporter activity 0.3470873562826689 0.4721569018547819 0.6368147996516846 1.0 1.0 52 P35609,P62942,O43865,P78417,P0DP25,Q03164,Q99996,O43707,P42858,Q9UMX0,Q9HD26 11 +Regulation of endothelial cell differentiation 0.4249610485336498 0.4709009648252142 0.6377114590149457 1.0 1.0 7 P35611 1 +Cytokine production involved in immune response 0.4000488609290681 0.4697276398766788 0.6385496178850252 1.0 1.0 10 P09601,P14174 2 +Guanine metabolic process 0.6913287955016318 0.4678272413296803 0.6399081380743925 1.0 1.0 2 P00492 1 +Intracellular protein transport 0.3869568743619135 0.4672395547236735 0.6403284969111775 1.0 1.0 342 O60830,P31751,P46379,Q96P70,Q8N8Q8,Q9Y282,Q9NS69,O43681,Q99595,O60725,Q13190,O00170,Q10713,P43307,Q9Y5X3,Q8N4H5,P30536,O75312,O00410,Q6ZWJ1,P55786,Q9UNH7,Q53H12,P33908,Q15648,P12270,Q15629,Q9P2W9,Q5T9L3,Q96RT1,O14964,O60763,P06493,Q92544,Q96QK1,Q8TEX9,O15260,P57105,Q9Y2T2,Q9BVK6,Q7L5D6,Q15388,Q15154,P49257,O14737,P50542,Q9H9H4,O75381,P10909,P31749,O43752,Q9Y3A6,Q9UHB9,Q8TB36,Q92572,Q15005,P41214,O95429,Q9Y5Y5,Q9Y5M8,P49841,O60749,O43865,O00159,Q16543,O95831,P35606,Q8TAG9,Q9Y5L4,P50402,Q14168,P40855,Q9Y5J7,Q9Y5J9,Q9UBV2,O14925,Q9C0E2,Q99567,Q8N1F7,O43464,P49815,Q92973,O75298,Q4V328,Q9GZY8,Q5JRX3,Q9BRG1,O60220,Q08209,Q9H3S7,Q9NR31,Q8TCT9,P33176,Q13438,Q13277,Q15363,Q9H6U6,P53365,Q13501,Q9UJY4,Q15437,P49755,O15027,Q969Q5 104 +Phosphatidylcholine acyl chain remodeling 0.6904409588635732 0.4651528361189907 0.6418220110799675 1.0 1.0 2 Q96N66 1 +Regulation of establishment or maintenance of cell polarity 0.3985019435423436 0.4621419003591174 0.6439795643275754 1.0 1.0 10 Q9H6U6,Q9NUQ9 2 +Positive regulation of cell activation 0.3493114682189692 0.461337822996529 0.644556252829608 1.0 1.0 46 P12956,Q9NUQ9,P31749,Q9HCL2,Q5RKV6,P30825,Q15418,P00813,P14174 9 +Negative regulation of myosin light chain phosphatase activity 0.6889612311334757 0.4607101509576802 0.6450065712237312 1.0 1.0 2 O75116 1 +Negative regulation of bicellular tight junction assembly 0.6889612311334757 0.4607101509576802 0.6450065712237312 1.0 1.0 2 O75116 1 +Negative regulation of response to external stimulus 0.3449669283389954 0.4603949285231812 0.6452327742300334 1.0 1.0 53 P28070,Q9Y4E8,Q96G23,Q8IXJ6,P80303,P00813 6 +Regulation of hormone levels 0.3206869642422605 0.4601024121456795 0.64544271278276 1.0 1.0 70 Q16836,O95563,Q08209,O43768,Q6NUM9,O95470,Q7Z7E8,P05023,P30536,O94788,Q6ZWJ1,Q9UNH7,Q15648,Q13555,P16435,P16220,Q14849,O60678,O75844 19 +Cell recognition 0.3424851067359042 0.4564322615562768 0.6480791709727667 1.0 1.0 26 Q9BY67,P50991,P78371,Q9NQC3,Q14157,P49368,Q8WTV0,P45880 8 +Negative regulation of ubiquitin dependent protein catabolic process 0.3424306425649113 0.4560308944865194 0.648367762246741 1.0 1.0 26 Q96KB5,Q8N163,Q9H2J4,P46379,P49069,O15372,Q96HY6,O15294 8 +Trna wobble base modification 0.487414865265016 0.4555511139430677 0.6487128037531429 1.0 1.0 4 O95163,Q9H9T3,Q969Y2 3 +Trna wobble uridine modification 0.487414865265016 0.4555511139430677 0.6487128037531429 1.0 1.0 4 O95163,Q9H9T3,Q969Y2 3 +Export from cell 0.308413427894199 0.4535675450795932 0.6501401173926937 1.0 1.0 154 P55011,O43633,Q16836,O95563,Q9H4A5,Q08209,O43768,Q9UBV2,Q5JRA6,Q16850,Q7Z7E8,Q15019,P05023,Q9H3S7,O00429,Q6ZWJ1,O95721,Q32P28,Q13277,Q9UNH7,Q9H4A6,P15311,O15126,Q99584,P09601,Q96KC8,Q13555,Q4KMQ2,P16220,P49755,Q5T9L3,Q9BRT2,P14174,Q96A65,O43760,Q4J6C6,Q86YV9,O14964,P35580,P0DP25,P16615,P35579,Q9BRK5,Q96QK1,Q96PC5 45 +Regulation of leukocyte proliferation 0.3438576397996783 0.4530091291859747 0.6505421678082426 1.0 1.0 28 Q92990,Q9HCL2,P30825,P00813,P14174 5 +Development of primary female sexual characteristics 0.3766494697553422 0.4529872442046335 0.6505579267129984 1.0 1.0 12 O95470 1 +Cellular homeostasis 0.3061127495861314 0.4523667265060394 0.6510048131629633 1.0 1.0 150 P55011,P62942,O95563,Q08209,Q9Y4W6,Q9H1E3,Q9NQC3,Q96A33,P42858,Q8NEW0,Q9BPX6,Q96TC7,Q07820,P52789,P0CG08,P05023,Q6ZWJ1,P78417,Q9HC07,Q93050,Q9Y6M7,Q8IYU8,P06576,P98194,P09601,Q9Y487,Q05086,Q4KMQ2,Q8N511,Q9HD20,O75880,P0DP25,P16615,P09429,P54105,Q9NWR8 36 +Oligosaccharide lipid intermediate biosynthetic process 0.4270500571952946 0.4523402860147469 0.6510238579495902 1.0 1.0 6 Q2TAA5,Q86YN1 2 +Proteasomal protein catabolic process 0.3158847419141943 0.4521664584699571 0.6511490696334445 1.0 1.0 168 O95155,P28072,Q9Y4X5,P46379,Q7L5D6,Q96A33,P28074,Q9H1I8,P20618,Q9Y5A7,Q9UBV2,Q14997,Q9Y297,Q9BW61,P61289,Q13200,Q96KB5,P28070,Q06787,P10909,P31749,P25787,Q8TCT9,Q13438,P33908,Q06323,O15294,Q8N163,Q92990,Q04323,P49841,P51665,Q9UL46,P17980,Q9UMX0,O15372,P49721,Q8IUR7,Q96HY6,Q9UBS8,Q8IXJ6,Q99436,P49427,P49069,Q15058,Q9UJX4,O75150 47 +Cerebellar cortex development 0.362140509029515 0.4518635289813225 0.6513672997168514 1.0 1.0 16 Q7Z4L5,O14949,O15020 3 +Positive regulation of nf kappab transcription factor activity 0.3397208135392709 0.4515774399202275 0.6515734254033516 1.0 1.0 24 P10909,Q8IUD2,Q92974,P32929,P19474,P23396,O15111,Q86UE4,Q96HY6 9 +Regulation of leukocyte differentiation 0.3414291618405093 0.4486604797607438 0.6536765977758303 1.0 1.0 26 P12956,O96005,P09429,P16220,P00813 5 +Odontogenesis of dentin containing tooth 0.4124557267611078 0.4484058217687342 0.6538603409681227 1.0 1.0 8 Q6P4Q7,P35613 2 +Activation of immune response 0.3458066230215627 0.4482390646283815 0.6539806724934387 1.0 1.0 50 P12956,P10909,P49770,P46379,Q9NUD5,Q07666,Q8WXF1,P15311,P23246,P09429,Q15233,P00813 12 +Response to bacterium 0.331763207818292 0.4469766445045124 0.6548919232280186 1.0 1.0 63 Q9NUQ9,P30536,P31749,Q8IXJ6,Q9NZ08,P08670,Q8WTV0 7 +Neuronal stem cell population maintenance 0.4255919628809718 0.446457958739877 0.655266474499945 1.0 1.0 6 Q9BXW9 1 +Viral protein processing 0.4119936119787644 0.4463660670492568 0.6553328400045211 1.0 1.0 8 Q10472,P27824,P49841 3 +Immune response regulating cell surface receptor signaling pathway 0.3451490947054694 0.4456914671278107 0.6558201291173682 1.0 1.0 31 P46379 1 +Negative regulation of programmed necrotic cell death 0.5543686313754448 0.4452564689553157 0.6561344225168388 1.0 1.0 3 Q92974 1 +Negative regulation of necrotic cell death 0.5543686313754448 0.4452564689553157 0.6561344225168388 1.0 1.0 3 Q92974 1 +Multi organism reproductive process 0.3077651838978679 0.4444268541702373 0.6567340017020178 1.0 1.0 154 Q8NB78,P50991,Q96QD8,P46379,Q07666,Q9BQE5,P50570,O95470,Q14997,Q15056,Q9Y508,Q14157,Q9H6S0,P41208,Q7Z7E8,Q15019,P31749,O94901,P35613,Q9Y2W6,Q99598,Q7Z739,Q15363,Q07021,P00813,Q15648,Q9BY67,Q9BTX1,P78371,Q05086,Q9H2U1,Q99417,Q08J23,Q9UIQ6,Q96PU8,Q8IZL8,Q9BPZ3,P45880,Q8IXJ6,Q15067,Q8NB90,A0AVF1,P06493,P26583,P43246,O75718,Q02790,P35579,Q9BXW9,Q8N2A8,P49368,Q14141 52 +Cellular response to virus 0.3396720056778495 0.4432914166797915 0.6575549633938222 1.0 1.0 25 Q06787,Q9Y4E8,Q14258,Q92890,Q92538,O43657,Q9NUD5,O15111,Q07021,Q07812 10 +Protein localization to microtubule end 0.6827463746670656 0.4422541215343804 0.6583053259749272 1.0 1.0 2 Q15555 1 +Regulation of long term synaptic potentiation 0.4180733137351158 0.4417214016126832 0.6586908208343045 1.0 1.0 7 Q13501,Q9BPZ3,P49841 3 +Vesicle tethering 0.4833370139862972 0.4415490047957673 0.6588155926649777 1.0 1.0 4 Q14849 1 +Muscle cell apoptotic process 0.3744625751689225 0.44120663037864 0.6590634135827678 1.0 1.0 12 P09601 1 +Phosphatidylinositol acyl chain remodeling 0.6818585380290069 0.4396447662838676 0.6601944124640553 1.0 1.0 2 Q96N66 1 +Nucleolar chromatin organization 0.4238624608306097 0.4395089880381413 0.6602927708433652 1.0 1.0 6 Q8IXJ6 1 +Asymmetric neuroblast division 0.5524433114066796 0.4392880221057522 0.6604528521191853 1.0 1.0 3 Q92974 1 +Neuroblast division 0.5524433114066796 0.4392880221057522 0.6604528521191853 1.0 1.0 3 Q92974 1 +Cytosolic transport 0.3144840105901822 0.437412197464917 0.661812439817417 1.0 1.0 72 Q9BVK6,Q96ED9,P49257,Q13190,O95249,Q9Y5X3,Q9H3S7,P33176,O43752,O60271,Q9UNH7,P15311,Q14203,Q15075,Q4J6C6,Q9UID3,Q8IUD2,Q96QK1,O15260 19 +Rna polymerase ii preinitiation complex assembly 0.4168317157982201 0.4365142866505886 0.6624636359854486 1.0 1.0 7 P09429,Q15545,O00268 3 +Actin filament based transport 0.401417010711857 0.4343541232282901 0.6640313066957371 1.0 1.0 9 Q8WXH0,O00159,O43707 3 +Regulation of tolerance induction 0.5507595712275791 0.4340950997376302 0.6642193837785189 1.0 1.0 3 P09429 1 +Gonadotropin secretion 0.6797869192068704 0.4335831681068928 0.6645911597790641 1.0 1.0 2 P82094 1 +Relaxation of muscle 0.4804999603588129 0.4318985677586163 0.6658151357783904 1.0 1.0 4 P05023 1 +Regulation of plasma membrane organization 0.4803135455044905 0.4312671319796236 0.666274146237408 1.0 1.0 4 P35579 1 +Embryonic organ morphogenesis 0.3357169176425036 0.4310269584521281 0.6664487687287344 1.0 1.0 23 Q8IZL8,O14641 2 +Hormone catabolic process 0.5493756294756524 0.429845610235236 0.6673079522328644 1.0 1.0 3 P42892 1 +Intermembrane lipid transfer 0.4078881371690784 0.4283483715067553 0.6683975068682411 1.0 1.0 8 P30536 1 +Mitochondrial acetyl coa biosynthetic process from pyruvate 0.4794056026747955 0.4281964427722761 0.6685081059269189 1.0 1.0 4 O95563 1 +Post golgi vesicle mediated transport 0.3421482687982595 0.428025868081603 0.6686322871946779 1.0 1.0 52 Q9H4A5,Q13439,Q9BZG1,P50570,Q9HD26,Q92572,Q9H4A6,P98194,O15126,Q01082,Q9UJY4,O60826,Q15276,Q8TAG9,Q96A65,Q4J6C6,O15027,Q567U6,Q9UPN3 19 +Positive regulation of secretion 0.3404911381734315 0.4276869345514308 0.6688790634569437 1.0 1.0 54 O43633,P55011,Q9Y5X3,Q9H4A5,O95563,Q9H3S7,O00429,O14964,P35580,Q9H4A6,P15311,P16220,P49755,Q5T9L3,P14174 15 +Sodium ion transmembrane transport 0.336389206815723 0.4274525941974323 0.669049706730273 1.0 1.0 24 P55011,P05023,Q6P4Q7,Q9Y6M7,Q4KMQ2,O43707,Q14BN4 7 +Peptidyl proline hydroxylation to 4 hydroxy l proline 0.4471223630342104 0.4274464629762787 0.6690541716267879 1.0 1.0 5 P07237,P13674,O15460 3 +Regulation of oxidative phosphorylation 0.3913516780872138 0.4274373004303627 0.6690608440256498 1.0 1.0 10 P14406,Q9BRT2 2 +Blastocyst development 0.3419816361543634 0.4271203933763367 0.6692916398779143 1.0 1.0 30 P31350,O75312,Q13895,Q13503,P61201,Q9NQC3,P00813,Q9BRT9,Q9NZN8 9 +Primary mirna processing 0.4788273615635046 0.4262449404304306 0.6699293736920127 1.0 1.0 4 P22626,Q9BXP5,O00571 3 +Endoplasmic reticulum to cytosol transport 0.366271199563973 0.425463096498188 0.6704991181548374 1.0 1.0 14 Q9UBV2,Q8TCT9 2 +Positive regulation of cell death 0.2892154225458805 0.4250614785276821 0.6707918584788586 1.0 1.0 124 O43464,P09601,P10909,P30536,Q8IXJ6,Q9Y4G8,O94788,O00429,P25054,Q96A26,Q9NR28,P30154,Q9NS69,P00403,O14737,P42858,Q9Y6C9,O95831 18 +Cellular response to manganese ion 0.6768274637466751 0.4249897394439917 0.6708441545351342 1.0 1.0 2 P05198 1 +Collateral sprouting in absence of injury 0.6768274637466752 0.4249897394439911 0.6708441545351347 1.0 1.0 2 Q8N0X7 1 +Embryonic placenta development 0.3621871820450631 0.4240188151612708 0.6715520915736017 1.0 1.0 15 P62993,Q15363,Q15648,P31749 4 +Primary alcohol metabolic process 0.3520387730569595 0.4236719816612746 0.6718050514842051 1.0 1.0 17 O94788,P30837,P43304,P51648 4 +Regulation of viral entry into host cell 0.4198444732105318 0.4234864991950545 0.6719403467190768 1.0 1.0 6 P07237,Q12899,P19474 3 +Purine containing compound transmembrane transport 0.4066598576499924 0.4229948456388468 0.672299021695447 1.0 1.0 8 Q8TB61 1 +Rrna base methylation 0.4192515454488404 0.4211367636571919 0.6736552174222785 1.0 1.0 6 Q96P11 1 +Regulation of b cell differentiation 0.6753477360165774 0.4207224678976117 0.6739577526980036 1.0 1.0 2 Q5JVF3 1 +Peptidyl tyrosine autophosphorylation 0.675051790470558 0.4198713879243069 0.6745794106148542 1.0 1.0 2 P27361 1 +Regulation of cardiocyte differentiation 0.6750517904705577 0.419871387924306 0.6745794106148548 1.0 1.0 2 Q9H2U1 1 +Negative regulation of cellular protein catabolic process 0.3423640089234708 0.4198093134610249 0.6746247606237292 1.0 1.0 32 Q96KB5,Q8N163,Q9H2J4,P46379,P49069,Q96QK1,O15372,Q96JB5,Q96HY6,O15294 10 +Polysaccharide metabolic process 0.3301642509962276 0.419368181396865 0.6749470744149835 1.0 1.0 20 Q7LGA3,P31751 2 +Cell volume homeostasis 0.4185586670527723 0.4183957963164561 0.6756577595288231 1.0 1.0 6 P55011,P54105 2 +Positive regulation of dna ligation 0.6744598993785187 0.4181716117394533 0.6758216498997149 1.0 1.0 2 P09429 1 +Negative regulation of canonical wnt signaling pathway 0.3510171533755477 0.4173025066175271 0.6764571552965524 1.0 1.0 17 P25054 1 +Positive regulation of stress fiber assembly 0.3563861680800745 0.4170295792461152 0.676656772312825 1.0 1.0 16 P09493,O75116 2 +Cytoplasmic pattern recognition receptor signaling pathway in response to virus 0.3647405395222287 0.4168305795094657 0.6768023335397637 1.0 1.0 14 Q9Y4E8,Q14258,Q92890,O43657,Q9NUD5,Q07021 6 +Regulation of neural precursor cell proliferation 0.3508748339977696 0.4164166101987084 0.6771051760414737 1.0 1.0 17 Q8IXJ6,P55209 2 +Methylguanosine cap decapping 0.4119739181979864 0.416303755841633 0.6771877445915113 1.0 1.0 7 Q6P2E9,Q96F86,Q8IU60,Q9BQG2,Q9NPI6,Q9UIV1 6 +Rna decapping 0.4119739181979864 0.416303755841633 0.6771877445915113 1.0 1.0 7 Q6P2E9,Q96F86,Q8IU60,Q9BQG2,Q9NPI6,Q9UIV1 6 +Peroxisome organization 0.3606507383743944 0.4150821788374895 0.6780817449746381 1.0 1.0 15 O75381,P40855,O00429,Q9GZY8,P50542 5 +Apoptotic process involved in morphogenesis 0.475434564122577 0.4148601008239159 0.678244319555372 1.0 1.0 4 Q07812,P30154 2 +Neural nucleus development 0.3372812264757436 0.4142248461928895 0.6787094471730335 1.0 1.0 19 Q8IXJ6,O15027,P24539,P0DP25 4 +Regulation of rig i signaling pathway 0.3968407876713734 0.4134459411948741 0.67927992131584 1.0 1.0 9 Q9Y4E8,Q9NUD5 2 +Multicellular organism reproduction 0.2883786214117516 0.4132493990158021 0.6794238988907808 1.0 1.0 124 P46379,Q07666,Q9BQE5,P50570,O95470,Q14997,Q9Y508,P41208,Q9H6S0,Q7Z7E8,Q15019,P31749,Q9Y2W6,Q15363,P00813,Q15648,Q9BTX1,Q9H2U1,Q99417,Q08J23,Q96PU8,Q8IZL8,Q9BPZ3,Q8IXJ6,Q15067,A0AVF1,P26583,O75718,Q9BXW9,Q8N2A8,Q14141 31 +Dna methylation 0.3330882215281567 0.4122290960092622 0.6801715128111978 1.0 1.0 23 Q03164,O75844 2 +Regulation of protein modification by small protein conjugation or removal 0.273008013120938 0.4118024415851198 0.680484231653236 1.0 1.0 87 Q9BTE7,Q13501,P62942,Q92564,Q92990,P31749,P30536,Q96DY7,Q05086,O60678,P49069,Q5VTR2,Q9UMX0,Q9Y297,Q96JB5,O15294 16 +Golgi disassembly 0.4424997767652096 0.4106217082789458 0.6813499433021171 1.0 1.0 5 Q08379,Q13190 2 +Cardiac muscle tissue development 0.3408737117904266 0.4085719743160442 0.682853801181543 1.0 1.0 32 P35609,O94788,Q8NDZ4,O75844,P09493,P16220 6 +Regulation of heterotypic cell cell adhesion 0.4734971868522279 0.4084100013272286 0.6829726920247892 1.0 1.0 4 Q14254,P41440,Q9H4A3 3 +Protein localization to membrane raft 0.4734971868522259 0.4084100013272228 0.6829726920247934 1.0 1.0 4 Q14254,P41440,P05026 3 +Positive regulation of cell cell adhesion mediated by cadherin 0.4734971868522236 0.4084100013272144 0.6829726920247996 1.0 1.0 4 Q07157,P55196,P41440 3 +Positive regulation of hexokinase activity 0.5421296915027044 0.4078795335252761 0.6833621191791797 1.0 1.0 3 Q9NQ88 1 +Regulation of hexokinase activity 0.5421296915027044 0.4078795335252761 0.6833621191791797 1.0 1.0 3 Q9NQ88 1 +Negative regulation of establishment of protein localization 0.3377063187768871 0.4075506846263701 0.683603576132465 1.0 1.0 28 Q16836,Q16850,Q08209,Q13438,P49257,Q9HD26 6 +Regulation of cell activation 0.3116879667304086 0.4065217643483322 0.6843592686904842 1.0 1.0 72 P12956,Q9NUQ9,P09601,Q92990,P31749,Q9HCL2,Q5RKV6,O96005,Q8WXW3,P30825,Q15418,P00813,P14174 13 +Cellular response to sterol depletion 0.4412939514286103 0.4062697279247633 0.684544425578486 1.0 1.0 5 Q15363 1 +Deadenylation dependent decapping of nuclear transcribed mrna 0.4724098028502106 0.4048062655938694 0.6856199228439488 1.0 1.0 4 Q9UIV1 1 +Female sex differentiation 0.365416754634184 0.404274818705393 0.6860106405725634 1.0 1.0 13 O95470 1 +Pyrimidine containing compound transmembrane transport 0.6691328795501674 0.4030181286097483 0.6869348881620838 1.0 1.0 2 Q9BSK2 1 +Response to interleukin 4 0.4020160094871013 0.4029142552222097 0.6870113040400243 1.0 1.0 8 P49736,P33993,P49327,Q14145,P39023,P08238,P11802 7 +Protoporphyrinogen ix metabolic process 0.4400870086009275 0.4019292853829192 0.6877360694235595 1.0 1.0 5 P06132 1 +Polyadenylation dependent snorna 3 end processing 0.4084716136862383 0.4018986847128307 0.6877585907596071 1.0 1.0 7 Q13868 1 +Negative regulation of proteolysis 0.3110990497769008 0.4000424268063205 0.6891252679926865 1.0 1.0 72 Q9H2J4,P46379,Q96KB5,P31749,Q15392,P19474,O15294,Q8N163,Q96KC8,P61201,P16435,O15372,P49755,Q96HY6,P78318,P49069,Q15418,Q96K76,Q92896 19 +Neuromuscular process 0.3374882257609078 0.3996328178148687 0.6894269811043949 1.0 1.0 29 P07196,Q7Z406,P78417,O43251,O75844,P50542,Q96QK1,Q8IZL8,Q8N0X7 9 +Golgi localization 0.4708320994965859 0.3995988593658749 0.6894519967118162 1.0 1.0 4 Q9Y678,P48444,P63104 3 +Cell surface receptor signaling pathway involved in cell cell signaling 0.2811067980352629 0.3990155370375984 0.6898817560736641 1.0 1.0 84 Q7Z4L5,Q14168,P31749,Q9UQB8,Q08209,O43815,P25054,Q9P1Z2,O14641,P50402,P49815,Q96K76,Q5T9L3 13 +Meiotic cell cycle 0.3333066600221888 0.3983404181863558 0.6903792708800593 1.0 1.0 58 Q9H6S0,Q9BTX1,Q92791,O94901,Q8IXJ6,P46379,Q9Y2W6,Q08379,P35579,Q08J23,Q9BXW9,Q8N2A8,Q9UQ84,Q9UQE7,Q9NTJ3,Q9BSJ2 16 +Pallium development 0.3424224150141916 0.3981636047657992 0.6905095919754154 1.0 1.0 43 Q96P11,P07196,O94901,P49841,Q96QD8,P62995,Q9NQC3,Q96N66,O14949,P50542,P07942,Q15058,Q8WXH0,Q8N3R9 14 +Regulation of response to wounding 0.3298064583845416 0.397868314510038 0.6907272573887764 1.0 1.0 22 P55011,Q4KMQ2,Q96G23,P10586 4 +Establishment or maintenance of bipolar cell polarity 0.3264942534505813 0.3937172297438914 0.6937898192404575 1.0 1.0 20 Q8N3R9,P15311,P57105,Q14168 4 +Positive regulation of mitochondrial fission 0.4064640187392112 0.3937063605430338 0.6937978448477304 1.0 1.0 7 O00429,Q9GZY8 2 +Centrosome separation 0.4687592537755278 0.3927959716955762 0.6944701801591988 1.0 1.0 4 P43487,Q9UNZ2,P37198 3 +Biomineralization 0.3469452648885689 0.3920971832857773 0.6949864086423652 1.0 1.0 17 P20248,Q6P4Q7,Q13464,O75844,Q4KMQ2,O75116,P18074,P22413,Q9Y4P1 9 +Negative regulation of phosphatase activity 0.3748738702210121 0.3916375818810925 0.6953260153546228 1.0 1.0 11 P62942,O95429,O75116 3 +Response to interleukin 7 0.3919700811850787 0.3914756578241084 0.695445678155473 1.0 1.0 9 P67809,P51858 2 +Positive regulation of receptor catabolic process 0.6646936963598744 0.3905922741667555 0.6960986372192275 1.0 1.0 2 Q96J02 1 +Regulation of dopamine receptor signaling pathway 0.6643977508138551 0.3897705192028863 0.6967062453275545 1.0 1.0 2 Q96QK1 1 +Positive regulation of dopamine receptor signaling pathway 0.6643977508138551 0.3897705192028863 0.6967062453275545 1.0 1.0 2 Q96QK1 1 +Thyroid gland development 0.5359670369216653 0.3895829896105103 0.6968449325665338 1.0 1.0 3 P27361 1 +Sarcomere organization 0.3909010640118139 0.3866943379832697 0.6989825083365635 1.0 1.0 9 P09493 1 +Columnar cuboidal epithelial cell development 0.3908681482260302 0.3865473554730848 0.6990913380510686 1.0 1.0 9 P31749,Q15382,P49841 3 +Plasma membrane tubulation 0.4357227488151514 0.3863668810344253 0.6992249745270627 1.0 1.0 5 P50570,Q5T0N5,Q9Y5X1,Q9UNF0 4 +Positive regulation of lymphocyte chemotaxis 0.5343398460627731 0.3848128841254309 0.7003760527011025 1.0 1.0 3 P78536,O95747 2 +Regulation of lymphocyte chemotaxis 0.5343398460627731 0.3848128841254309 0.7003760527011025 1.0 1.0 3 P78536,O95747 2 +Regulation of t cell chemotaxis 0.5343398460627731 0.3848128841254309 0.7003760527011025 1.0 1.0 3 P78536,O95747 2 +Regulation of post translational protein modification 0.5338691298762331 0.3834378031672532 0.7013951783456362 1.0 1.0 3 Q32P28 1 +Synaptic vesicle localization 0.3731889565992813 0.383289002604244 0.7015054924513744 1.0 1.0 11 P50570,Q9Y2T2,P33176 3 +Inositol phosphate catabolic process 0.434766367753815 0.3829847678275628 0.7017310581364098 1.0 1.0 5 Q9NX62 1 +Demethylation 0.332406582795608 0.3817033983033431 0.7026813791302229 1.0 1.0 19 Q16850,Q9UPP1 2 +Ubiquinone metabolic process 0.4086239976879908 0.3796930083731807 0.7041733107070713 1.0 1.0 6 Q8NI60 1 +Regulation of chromatin organization 0.3317317896439558 0.3772401959206786 0.7059951111274672 1.0 1.0 19 P12270,Q8NEY8,Q9UPP1 3 +Negative regulation of nik nf kappab signaling 0.4331342308755661 0.3772368074203414 0.7059976290688319 1.0 1.0 5 O43657 1 +Heart valve development 0.3957634239015152 0.3762945641939685 0.7066979200023122 1.0 1.0 8 P43243,P20248,O75116 3 +Organelle inheritance 0.388408696004569 0.3756055871503697 0.7072101364846264 1.0 1.0 9 P27361,Q08379,Q13190,P06493 4 +Er overload response 0.4325546441023932 0.3752029583710803 0.7075095301912431 1.0 1.0 5 Q96A33,P49841 2 +Skeletal muscle organ development 0.3312003253519147 0.3745367187758507 0.7080050435392986 1.0 1.0 26 Q7Z406,Q08209,P61201,P50402,P60660,Q9BRT2 6 +Cell migration involved in gastrulation 0.6587747854394839 0.3743172807038395 0.7081682769129773 1.0 1.0 2 Q4VCS5 1 +Negative regulation of epidermal growth factor activated receptor activity 0.4316733322377035 0.3721177111482728 0.7098052101419043 1.0 1.0 5 Q9BRG1 1 +Positive regulation of protein kinase activity 0.321053885244344 0.370706383442694 0.7108562352883991 1.0 1.0 65 P12956,Q99627,P10909,P31749,Q9Y4G8,P0DP25,Q8NDZ4,Q8WXW3,O14641,Q9H2K8,P14174 11 +Neural tube formation 0.3295174815575361 0.3702889064026301 0.7111672387173125 1.0 1.0 25 O15031,O60313,Q15363,O14641,P49815 5 +Regulation of tissue remodeling 0.4059340102102547 0.3694140267773602 0.7118191443862592 1.0 1.0 6 Q08209 1 +Hydrogen peroxide biosynthetic process 0.5286216873603277 0.368257253256986 0.7126814232233367 1.0 1.0 3 Q15067 1 +Regulation of vesicle mediated transport 0.2874954639713036 0.3676807546349318 0.7131112924296115 1.0 1.0 128 O43633,P57105,P31751,Q08209,P30533,P50570,Q9HD26,Q9H3S7,Q15019,P10909,Q9NR31,P15311,P98194,Q8WTV0,Q9H223,P09601,Q4KMQ2,P61978,P49815,Q9P2W9,P35609,Q4J6C6,Q4V328,O14964,P0DP25,P16615,P09429 27 +Negative regulation of defense response 0.3367690005370329 0.3653033954037505 0.714884944128277 1.0 1.0 35 Q96KB5,P28070,Q9Y4E8,Q9UIV1,Q9Y3Z3,Q8IXJ6,Q14166,O43657,P19474,Q07021,Q96QK1,P00813 12 +Regulation of neuroblast proliferation 0.460171750074024 0.3650957293072637 0.7150399487245869 1.0 1.0 4 P35221,P35222,O60341 3 +Response to wounding 0.2645401044771647 0.3641718882233016 0.7157296577311851 1.0 1.0 91 P55011,O43633,Q08209,P12814,P10586,Q5JRA6,P30536,Q96AY3,Q8WTV0,Q99707,P09601,Q96G23,P00374,Q4KMQ2,P09493,P38435,P07196,Q86YV9,Q8WUX9,P35579,P42785 21 +Cardiac muscle cell proliferation 0.4041379795565311 0.3626007119652261 0.7169031783474507 1.0 1.0 6 Q8NDZ4 1 +Cytoplasmic sequestering of protein 0.3685493136459681 0.3605145178180869 0.7184624018756565 1.0 1.0 11 O60826,Q9UN86,Q9HD26 3 +Regulation of protein localization to cell surface 0.354526514030388 0.3601639110688989 0.718724561006983 1.0 1.0 14 P35609,Q13277,Q9HD26,P31749 4 +Barbed end actin filament capping 0.3684378907721524 0.3599715525788156 0.7188684072578999 1.0 1.0 11 Q13045,Q9BPX3,P35611,P35241,P35612,Q9UEY8,P52907,Q6IBS0 8 +Cellular response to vitamin 0.403182842533061 0.3589938251722598 0.7195997086066921 1.0 1.0 6 Q15648 1 +Camera type eye morphogenesis 0.3975945367128262 0.3581071111424515 0.720263157568708 1.0 1.0 7 Q15555,Q07812 2 +Regulation of cell cell adhesion mediated by cadherin 0.4274289099525963 0.3573859232884465 0.7208029134647487 1.0 1.0 5 Q07157,P55196,O75955,P41440 4 +Sequestering of actin monomers 0.6519680378810349 0.3560254449994301 0.7218215096888572 1.0 1.0 2 Q6IBS0 1 +Cellular respiration 0.2749518756973388 0.3518977557131751 0.7249149423709507 1.0 1.0 109 P00846,O75964,Q9UDW1,Q13423,P22695,P03886,O43676,P14406 8 +Cardiac muscle cell action potential 0.3401071876649931 0.3504650161091945 0.7259897404472129 1.0 1.0 17 P16615,Q99996,P05023,P0DP25 4 +Cell communication by electrical coupling 0.3891958052298384 0.348881571575205 0.7271782207189097 1.0 1.0 8 P0DP25 1 +Pigment biosynthetic process 0.3240105034139295 0.3484669655407749 0.7274895186785189 1.0 1.0 23 P22830,P30536,Q9Y4G8,Q06203,P06132,P00813 6 +Epidermis development 0.3316358933932474 0.3484580605403105 0.7274962052987861 1.0 1.0 54 P67809,Q9Y6M7,P16615,Q16739,P51648,Q8NEY8 6 +Regulation of interleukin 1 mediated signaling pathway 0.6487126368748201 0.3474413431194679 0.728259778208245 1.0 1.0 2 Q86Y07 1 +Vesicle fusion to plasma membrane 0.5210761423383743 0.3469180264208724 0.7286529035880638 1.0 1.0 3 O95721 1 +Striated muscle contraction 0.3259294861113778 0.3450447227819995 0.7300607490391104 1.0 1.0 25 Q7Z406,P78417,P0DP25,P16615,Q99996,P09493 6 +Apoptotic dna fragmentation 0.4234827648858903 0.3438822747905063 0.7309348225185393 1.0 1.0 5 O95831,Q9Y2C4 2 +Ribonucleoside monophosphate biosynthetic process 0.3263296722538413 0.3418703805715639 0.7324484409345433 1.0 1.0 19 P00813 1 +Mannosylation 0.380691535903313 0.3418140430740056 0.7324908406199697 1.0 1.0 9 Q2TAA5,Q9H9S5 2 +Regulation of lymphocyte activation 0.3248806091022383 0.3410668846152538 0.7330532303734811 1.0 1.0 60 P12956,Q9NUQ9,Q92990,P31749,Q9HCL2,Q5RKV6,O96005,Q8WXW3,P30825,P00813,P14174 11 +Genomic imprinting 0.5189461219656768 0.3410015114324231 0.7331024439047265 1.0 1.0 3 Q6PD62,P49711 2 +Regulation of muscle adaptation 0.3535377641006125 0.3408907755345825 0.7331858094066739 1.0 1.0 13 P11413,Q08209,Q13555,P02545,P50750,P16615,O75116,Q13464 8 +Activation of gtpase activity 0.3327492745264865 0.3408862652332062 0.7331892049715469 1.0 1.0 18 P31751 1 +Phenol containing compound metabolic process 0.3643910958355056 0.3403823129991831 0.7335686365430591 1.0 1.0 11 P21964,Q15648,P16930,Q9Y4G8 4 +Regulation of guanyl nucleotide exchange factor activity 0.4522859878559024 0.3403741730198706 0.7335747657637515 1.0 1.0 4 P05198,P16949 2 +Positive regulation of interleukin 2 production 0.397892561056238 0.3392280095306869 0.7344379703749755 1.0 1.0 6 Q92990,Q01082 2 +Male meiosis i 0.6454572358686053 0.3389653932194905 0.7346358006433318 1.0 1.0 2 Q15645 1 +Regulation of atpase coupled calcium transmembrane transporter activity 0.6454572358686052 0.3389653932194893 0.7346358006433327 1.0 1.0 2 Q6YHU6 1 +Positive regulation of translation 0.323376059668328 0.3384062077371443 0.7350570967085035 1.0 1.0 61 P98179,Q7Z478,Q07666,Q9H074,Q9BRP8,P51116,Q96P11,Q06787,O15031,Q7Z739,Q07021,P67809,Q14011,O60506,P08670,Q9H2U1,Q9BRT2,Q9Y2R0,Q567V2 19 +Mast cell activation 0.3863974079903746 0.3373808247430234 0.7358298378126258 1.0 1.0 8 Q9UNH7,P09601 2 +Cell cell recognition 0.3469633595744263 0.337210876102288 0.7359579390257531 1.0 1.0 15 P49368,P78371,P50991,P45880 4 +Cellular modified amino acid catabolic process 0.3922049426627592 0.3369734033561542 0.7361369497925452 1.0 1.0 7 Q9UHG3 1 +Positive regulation of ion transmembrane transport 0.3293288087771802 0.3342706145815041 0.7381753625200951 1.0 1.0 30 P35609,P78417,P0DP25,Q4KMQ2,Q99996,O43707,P42858 7 +Adaptive immune response 0.3337477870928218 0.3338356487218383 0.7385035813129694 1.0 1.0 47 Q9NZ08,Q9NUQ9,P00813,Q6P179 4 +Positive regulation of dna binding 0.3422101908149901 0.3336353646634246 0.7386547287255132 1.0 1.0 16 Q8IXJ6,P09429,Q96HY6,P0DP25 4 +Positive regulation of g1 s transition of mitotic cell cycle 0.3249219451792009 0.3327631310307242 0.7393130908132075 1.0 1.0 19 P31350,P31749 2 +Cytoplasmic sequestering of nf kappab 0.4496008936463171 0.3321193754025766 0.7397991202702534 1.0 1.0 4 Q9UN86 1 +Cardiac cell development 0.3518392515000291 0.3320206335418053 0.7398736786456457 1.0 1.0 13 P35609,P02545,O75844,P06493 4 +Tetrapyrrole biosynthetic process 0.3518014949879497 0.3318240389141241 0.7400221313336943 1.0 1.0 13 P22830,P06132,P30536 3 +Protein maturation by protein folding 0.3957720005591382 0.331408266132049 0.7403361218927467 1.0 1.0 6 O76024,P62942,O00170 3 +Female meiosis i 0.6422018348623904 0.330598968932849 0.740947425135297 1.0 1.0 2 Q15645 1 +Protein localization to cytoplasmic stress granule 0.390018919947087 0.3285144669937757 0.7425227076322927 1.0 1.0 7 P67809,P31483 2 +Regulation of protein acetylation 0.3256556583114499 0.3279250008566745 0.7429683700758585 1.0 1.0 27 Q03164,Q01105 2 +Animal organ formation 0.3897451096621239 0.3274596424684148 0.7433202624405224 1.0 1.0 7 P35222,P98164,P28482,P27361,Q8NC56,Q02750 6 +Glycerophospholipid catabolic process 0.3894952639012501 0.3264980587972102 0.7440475577597676 1.0 1.0 7 Q8WTV0 1 +Regulation of mrna catabolic process 0.2862233683405022 0.3264695161115739 0.7440691495578462 1.0 1.0 80 P67809,Q92804,Q5PRF9,O00178,P31749,P98175,Q14011,P08670,O60506,Q9H2U1,Q99729,P35637,Q9H074,Q13868,Q969T7,Q9NZN8 16 +Regulation of endodeoxyribonuclease activity 0.3942144352618895 0.325703181912555 0.7446489365827833 1.0 1.0 6 P31749 1 +Regulation of cardiac muscle cell membrane repolarization 0.4470801480777387 0.3244472008906038 0.7455994895495541 1.0 1.0 4 O75844 1 +Positive regulation of peptidase activity 0.3329161381353712 0.3233223115221014 0.7464511585065556 1.0 1.0 45 O43464,Q96A26,Q9NR28,Q9UL46,P09429,O14737,Q9BXK5,Q14997,P61289,O95831,Q06323,Q96HY6 12 +Regulation of cell cycle g1 s phase transition 0.3327228055095981 0.3233047163555162 0.7464644825085722 1.0 1.0 46 P31749,P31350,Q96DY7,P25054,Q9UL46,Q15058,P61289,O95905,Q06323,Q96HY6 10 +Outer ear morphogenesis 0.5118413262285542 0.3216179836854334 0.7477421181393091 1.0 1.0 3 P28482,P27361 2 +Positive regulation of vasculature development 0.3231174901272077 0.3211586659100013 0.7480901540630316 1.0 1.0 19 Q9NZ08 1 +Enteroendocrine cell differentiation 0.3925369205886992 0.3195958135613053 0.7492747483576219 1.0 1.0 6 P49841,P31749 2 +Skin development 0.3325334056556606 0.3189748066956239 0.7497456170243959 1.0 1.0 42 Q16739,Q15392,Q8NEY8,P16949 4 +Response to hepatocyte growth factor 0.3921435146620216 0.3181691504187962 0.7503566321817356 1.0 1.0 6 Q8IXJ6,P16220 2 +Negative regulation of lipid biosynthetic process 0.3675182149239087 0.3166445629490121 0.7515133180035227 1.0 1.0 10 O60678,Q8WXW3 2 +Sodium ion homeostasis 0.3867412406575549 0.3159573563693658 0.7520348759724405 1.0 1.0 7 P55011,Q9Y5X3 2 +Regulation of epithelial cell migration 0.331553431729125 0.313832546531596 0.7536482237304423 1.0 1.0 46 Q9H3S7,P57105,P09601,P31749,Q15555,Q9NQC3,P06576,Q9H6U6,P42785,Q8WTV0 10 +Mitochondrial genome maintenance 0.3740349331521677 0.3133655500798606 0.7540029541492139 1.0 1.0 9 O60313 1 +Positive regulation of extrinsic apoptotic signaling pathway 0.3667694016189599 0.3133012027348127 0.7540518364517677 1.0 1.0 10 P30154 1 +Epithelial tube formation 0.3235406296781321 0.3131332122685488 0.7541794572516516 1.0 1.0 27 O15031,O60313,Q15363,O14641,P49815 5 +Pyrimidine ribonucleoside triphosphate metabolic process 0.358647209359843 0.3130326646034359 0.7542558455925588 1.0 1.0 11 P17812,Q9NRF8,Q13232 3 +Positive regulation of cell differentiation 0.2846496323096861 0.3118757076422971 0.7551349848529769 1.0 1.0 130 P12956,Q9Y4G8,Q13439,Q8WUJ1,P55209,P30536,P31749,O15031,Q86X55,Q7L576,Q9Y6C9,P00813,Q9UQB8,P16435,P16220,P07196,P35611,Q8IXJ6,Q15418 19 +Regulation of rna polymerase ii regulatory region sequence specific dna binding 0.5075884259511858 0.3102793294729187 0.7563485487007477 1.0 1.0 3 Q96HY6 1 +Apoptotic mitochondrial changes 0.327428238764098 0.3094884049219914 0.756950031053963 1.0 1.0 32 P10909,P31749,O00429,Q96A26,O60313,O14737,P45880 7 +Terpenoid metabolic process 0.3169497803875503 0.3092789074751228 0.757109374366818 1.0 1.0 22 O43464,O94788,O60678,Q6NUM9,P51648 5 +Positive regulation of interleukin 10 production 0.5067247106932022 0.308001209361445 0.75808141210815 1.0 1.0 3 Q8WXW3 1 +Regulation of extrinsic apoptotic signaling pathway 0.3278700854080101 0.307718510076379 0.7582965337261842 1.0 1.0 33 O43464,Q07820,P09601,O95677,P31749,P49841,P30154,P02545,P26583,P42858,P61289 11 +Positive regulation of protein catabolic process 0.3023520100813033 0.3050567411139473 0.7603229373672806 1.0 1.0 72 Q9UBS8,P10909,Q9Y4X5,P31749,P49841,Q8IXJ6,P46379,P25054,Q96JB5,Q9Y5A7,Q13190,P15311,O60826,Q9UMX0,Q96QK1,Q9BW61,O75150,Q96HY6 18 +Inositol phosphate metabolic process 0.3881720290275606 0.3038882840055931 0.7612130039633835 1.0 1.0 6 Q9NX62 1 +Regulation of small gtpase mediated signal transduction 0.3297535192074933 0.3034458391449449 0.761550116781365 1.0 1.0 38 Q96RT1,Q13501,Q9NUQ9,P16949,Q15555,Q15058,P49815,Q5VZ89,O15294 9 +Cellular response to interferon gamma 0.3172153314800572 0.3020424267885536 0.7626197205136247 1.0 1.0 23 P33176,Q6ZWJ1,O00159,O60506,P08670,Q15648 6 +Positive regulation of rna splicing 0.3170055589103873 0.3006286943088584 0.7636976481765501 1.0 1.0 23 Q96QD8,Q14011,P38159,P98179 4 +Vesicle transport along microtubule 0.3471565592396209 0.3000143805772002 0.7641661864919096 1.0 1.0 12 Q9Y2T2,P42858 2 +Macropinocytosis 0.5034811189143863 0.2995211343386522 0.7645424489034283 1.0 1.0 3 Q9BZG1 1 +Ventricular septum development 0.3554896142433316 0.2982364237980638 0.765522723795212 1.0 1.0 11 P43243,P20248,Q13308,Q86V48,Q06330,Q9ULT8,P63010,P98164,O96028,O94813 10 +Nucleoside triphosphate biosynthetic process 0.328218820752316 0.2979559751112945 0.7657367650435443 1.0 1.0 36 P00846,O75964,P00403,P06576,Q9NRF8,P24539,Q13232 7 +Negative regulation of nf kappab transcription factor activity 0.3397203941450923 0.2974132056803774 0.766151062905092 1.0 1.0 15 O60826,Q96JB5,Q9UN86,P19474 4 +Aspartate transmembrane transport 0.4376665679597166 0.2964776580876799 0.7668653266879133 1.0 1.0 4 O75746,Q9UJS0,Q8TDW0 3 +L aspartate transmembrane transport 0.4376665679597151 0.2964776580876755 0.7668653266879166 1.0 1.0 4 Q15758,O75746,Q9UJS0 3 +Fermentation 0.5022782702076584 0.2964068008840679 0.7669194322117348 1.0 1.0 3 Q9NQ88 1 +Glycolytic fermentation 0.5022782702076584 0.2964068008840679 0.7669194322117348 1.0 1.0 3 Q9NQ88 1 +Adherens junction organization 0.3446602003077591 0.2951117951756521 0.7679084795394344 1.0 1.0 13 P35611 1 +Nuclear migration 0.3446360328285065 0.294989195484413 0.7680021334096525 1.0 1.0 13 Q14203,O94901,Q15154,Q9UH99,Q8WXH0 5 +Positive regulation of organelle organization 0.3045294263449793 0.2942456306046975 0.7685702149361227 1.0 1.0 168 P31751,Q9BVK6,Q8TBX8,P49257,O14737,P42858,Q9NZN8,Q9NTJ3,O00429,Q96A26,Q16625,O95429,Q7L576,Q9H6U6,P21796,O43464,Q9UHV9,Q14203,P12270,Q66GS9,Q9UQB8,P78371,Q9UN86,P48681,Q9H2U1,Q9P2S5,Q15047,Q99996,Q96C92,P09493,O75116,Q9P2W9,P35609,Q9BPX3,Q8IXJ6,Q15555,Q9GZY8,Q9UJX4,P23246,Q8N2A8,P49368,Q96QK1,Q8NEY8,O15260,O15144 45 +Axonal transport 0.3159444049013831 0.2934958139365402 0.7691431986876351 1.0 1.0 23 P07196,O60333,Q9Y2T2,O60313,Q14168 5 +Telencephalon development 0.3290361091745339 0.2923192340381769 0.7700425541048119 1.0 1.0 45 Q96P11,P07196,O94901,P49841,Q96QD8,P62995,Q9NQC3,Q96N66,O14949,P50542,P07942,Q15058,Q8WXH0,Q8N3R9 14 +Regulation of cyclic nucleotide phosphodiesterase activity 0.5000545284779279 0.2906929628580029 0.7712861541288099 1.0 1.0 3 P0DP25 1 +Positive regulation of osteoblast proliferation 0.6259248298313166 0.2904553393739824 0.7714679127223736 1.0 1.0 2 P20248 1 +Regulation of neutrophil migration 0.3746689389069705 0.2904283654452696 0.7714885459178307 1.0 1.0 8 O00429,Q00013 2 +Response to catecholamine 0.3413795471085855 0.2899238221737178 0.7718745165029515 1.0 1.0 14 Q8IXJ6,Q96QK1,P50570 3 +Skeletal system development 0.3247996418854791 0.2887313901587696 0.7727869393875313 1.0 1.0 54 Q7RTS9,Q15125,Q9NX62,Q32P28,O75844,O95470,Q92896,Q96HY6 8 +Negative regulation by host of viral process 0.4987979447315809 0.2874894620546143 0.773737569606723 1.0 1.0 3 Q9H1E3 1 +Autophagosome organization 0.3207635539672744 0.2867751174346212 0.774284516471792 1.0 1.0 28 P53365,Q5MNZ6,Q9Y2L5,Q86Y82,P50851,Q15286,Q9H2M9,Q8TBX8,P16615,Q9ULC3,Q9H0U4,Q15042,Q9UMX0,Q9Y4P1 14 +Negative regulation of neuron differentiation 0.3735587192297815 0.2860933467763946 0.7748066271893248 1.0 1.0 8 O60271,Q15648 2 +Atrial septum development 0.6232613199171408 0.2841609387612601 0.7762870484192455 1.0 1.0 2 P20248 1 +Atrial septum morphogenesis 0.6232613199171408 0.2841609387612601 0.7762870484192455 1.0 1.0 2 P20248 1 +Cardiac atrium development 0.6232613199171408 0.2841609387612601 0.7762870484192455 1.0 1.0 2 P20248 1 +Positive regulation of isotype switching to iga isotypes 0.6232613199171408 0.2841609387612601 0.7762870484192455 1.0 1.0 2 P43246 1 +Cardiac atrium morphogenesis 0.6232613199171408 0.2841609387612601 0.7762870484192455 1.0 1.0 2 P20248 1 +Regulation of macrophage proliferation 0.6226694288251016 0.2827728786802313 0.7773509458392995 1.0 1.0 2 P27361 1 +Positive regulation of macrophage migration 0.6226694288251016 0.2827728786802313 0.7773509458392995 1.0 1.0 2 P27361 1 +Positive regulation of macrophage chemotaxis 0.6226694288251016 0.2827728786802313 0.7773509458392995 1.0 1.0 2 P27361 1 +Response to nutrient 0.3201594664542366 0.2826068865895666 0.7774782007190004 1.0 1.0 28 P09601,O43768,P30536 3 +Negative regulation of transforming growth factor beta receptor signaling pathway 0.3435270890005042 0.2821979170190004 0.7777917554220857 1.0 1.0 12 Q9UNH7,P62942,Q92896 3 +Nephric duct development 0.6223734832790822 0.2820803119937574 0.7778819292449739 1.0 1.0 2 Q15375 1 +Nephric duct morphogenesis 0.6223734832790822 0.2820803119937574 0.7778819292449739 1.0 1.0 2 Q15375 1 +Smooth muscle tissue development 0.6223734832790822 0.2820803119937574 0.7778819292449739 1.0 1.0 2 Q12959 1 +Protein targeting to lysosome 0.3418443366279656 0.2809046750401374 0.7787835148082556 1.0 1.0 13 Q9Y2T2 1 +Positive regulation of potassium ion transport 0.3432066085052492 0.2806368567506829 0.7789889439692672 1.0 1.0 12 P35609,Q4KMQ2,Q99996,P33176 4 +Positive regulation of catabolic process 0.2975676254715917 0.2799327895851508 0.7795290700496342 1.0 1.0 157 Q5PRF9,O00178,P31751,P46379,Q8TBX8,Q9H074,Q9Y5A7,Q13190,Q969T7,P42858,Q9NZN8,P10909,P31749,P15311,P19474,P21796,Q86UE4,P67809,P09601,P25054,O60506,Q9H2U1,Q13868,O75116,O60826,Q9UMX0,P49815,Q96JB5,Q96HY6,Q9UBS8,Q8IXJ6,P09429,Q96QK1,O75150 34 +Cellular response to lipoprotein particle stimulus 0.3811237457896093 0.2791042571204258 0.7801648161939989 1.0 1.0 6 P31749 1 +Ribosomal large subunit export from nucleus 0.3768574789802615 0.2790479506468352 0.7802080263873119 1.0 1.0 7 Q99567 1 +Positive regulation of axonogenesis 0.3163688386958875 0.2784854151405049 0.7806397594375167 1.0 1.0 19 Q7L576,P07196,Q13439 3 +Regulation of protein localization 0.3398979258403395 0.2774811270314767 0.7814106955287239 1.0 1.0 245 P55011,Q16836,P62942,O95563,Q9H4A5,P31751,Q08209,Q9BV73,Q9NQC3,Q9Y282,Q15154,O43768,O14737,Q10713,Q9HD26,Q16850,Q9H3S7,Q9NR31,P31749,O75312,O00410,O43752,Q6ZWJ1,O00429,Q32P28,P33176,Q13438,P55786,Q9H4A6,Q9C0E2,P15311,Q13277,P19474,O00264,Q9H6U6,P98194,Q01082,O43464,Q13501,Q96KC8,P12270,Q66GS9,Q13895,P78371,P25054,Q96C92,O75116,Q96JB5,P49755,Q96HY6,Q5T9L3,Q9BRT2,P35609,Q96D46,Q4V328,P35580,Q9GZY8,Q14C86,P06493,P50402,Q92544,P49368,Q96QK1 63 +Nucleus localization 0.338836602396661 0.2767298264835329 0.7819875676826968 1.0 1.0 14 Q14203,O94901,Q15154,Q9UH99,Q8WXH0 5 +Aortic valve morphogenesis 0.4936502575404495 0.2745586298920205 0.7836553537452091 1.0 1.0 3 O75116 1 +Response to reactive oxygen species 0.3245558633211815 0.2711248392273057 0.7862950178805228 1.0 1.0 36 Q99720,P09601,P31749,Q05086,P09493 5 +Cellular response to light stimulus 0.3190961505036639 0.2685220134315296 0.7882975325876129 1.0 1.0 29 Q06787,Q96KB5,P31751,Q15555,Q96RU2,Q9H2U1,Q07812,Q96K76 8 +Leukocyte cell cell adhesion 0.3254685579215426 0.2667198326233778 0.7896848827006164 1.0 1.0 47 Q5JRA6,Q9NUQ9,Q92990,P31749,Q9HCL2,Q9H4A6,P09429,P30825,P00813 9 +Negative regulation of microtubule polymerization or depolymerization 0.3389527882122238 0.2664821118153693 0.7898679341972197 1.0 1.0 13 P25054 1 +Natural killer cell differentiation 0.6152707901746135 0.2657534856804925 0.7904290683673216 1.0 1.0 2 O95251 1 +Regulation of dna binding transcription factor activity 0.3057206898374832 0.2652184283510526 0.7908411993172857 1.0 1.0 68 Q96RT1,O75381,P09601,P10909,P31749,Q08209,Q00577,Q8IUD2,Q9UN86,O14641,P32929,P19474,O60826,Q9Y297,Q96JB5,Q86UE4,Q96HY6 17 +L amino acid transport 0.3385582095219315 0.2645274025646174 0.791373552389516 1.0 1.0 13 P30825 1 +Response to cocaine 0.3620841717691481 0.2640633546483152 0.7917311006796179 1.0 1.0 9 Q05086,P50570 2 +Sensory organ development 0.3115985463163009 0.2638274046013955 0.791912916678498 1.0 1.0 64 O95677,Q15555,O94788,Q9Y6M7,P48681,P08670,O14641,Q15293,Q9H0W8,Q8IZL8,Q9Y4P1 11 +Action potential 0.3113626821671988 0.2630662829058628 0.792499491225872 1.0 1.0 23 P05023,Q7Z406,P0DP25,P16615,Q99996 5 +Positive regulation of cell cycle g1 s phase transition 0.3138896210980421 0.2627749061090041 0.7927240780302038 1.0 1.0 25 P31350,Q96HY6,P31749 3 +Multi multicellular organism process 0.319007427466489 0.2615139883504479 0.7936961636090516 1.0 1.0 30 Q7Z7E8,P35613,P31749,Q96QD8,Q15363,Q9UIQ6,Q02790,Q9BQE5,Q07021,Q8IZL8,Q15648 11 +Oocyte construction 0.4873173385181773 0.259081987138795 0.7955719825990375 1.0 1.0 3 Q8N2A8 1 +Negative regulation of rig i signaling pathway 0.4238851687693378 0.2575644210011014 0.7967430913438835 1.0 1.0 4 Q07021 1 +Adherens junction assembly 0.422564406277753 0.2539674031976793 0.7995207410949139 1.0 1.0 4 Q13177,P35222,P18206 3 +Copi coated vesicle budding 0.3947876386379164 0.2517904876909631 0.801203010219877 1.0 1.0 5 Q15363,P49755 2 +Regulation of defense response 0.258988432402354 0.2514363170959288 0.8014767923636077 1.0 1.0 95 P12956,Q9Y4E8,Q96KB5,P28070,Q9NZ08,Q9NUD5,Q9UNH7,P19474,Q07021,Q15233,P00813,Q15648,Q9BY67,Q9Y3Z3,Q8WXF1,Q16543,Q8IXJ6,O43657,P26583,O75844,P23246,P09429,Q9BXW9,Q96QK1,Q9UIV1 25 +Cell differentiation involved in embryonic placenta development 0.6087599881621839 0.2512902356150553 0.8015897238649821 1.0 1.0 2 Q9ULT8 1 +Positive regulation of extrinsic apoptotic signaling pathway via death domain receptors 0.6087599881621839 0.2512902356150553 0.8015897238649821 1.0 1.0 2 Q9UNN5 1 +Positive regulation of neurotransmitter secretion 0.6084640426161644 0.2506443712587343 0.8020890731617392 1.0 1.0 2 Q15042 1 +Regulation of presynaptic cytosolic calcium ion concentration 0.6084640426161643 0.2506443712587334 0.8020890731617398 1.0 1.0 2 P20020 1 +Regulation of lipoprotein particle clearance 0.3687200369407598 0.2498010852729218 0.8027411804238798 1.0 1.0 7 Q9Y2B0,P61978,P30533 3 +Calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules 0.4831281317490438 0.2491106646030703 0.8032751802910583 1.0 1.0 3 P98194 1 +Endosome organization 0.3180736662348547 0.2490422016479192 0.8033281373782877 1.0 1.0 31 O43633,Q13501,O43752,O14964,Q96ED9,Q15075,Q8WUX9,Q9BRG1 8 +Regulation of spontaneous synaptic transmission 0.483009738501815 0.2488319789289868 0.8034907533376288 1.0 1.0 3 P55011 1 +Spontaneous synaptic transmission 0.483009738501815 0.2488319789289868 0.8034907533376288 1.0 1.0 3 P55011 1 +Negative regulation of proteolysis involved in cellular protein catabolic process 0.3159932965260923 0.2473166042738764 0.8046632095041111 1.0 1.0 29 Q96KB5,Q8N163,Q9H2J4,P46379,P49069,O15372,Q96HY6,O15294 8 +Negative regulation of developmental growth 0.3515188022803516 0.247305548855665 0.8046717647778701 1.0 1.0 10 O60271,Q9NQC3 2 +Regulation of neuron migration 0.3679583759664405 0.2471188838288706 0.8048162196876816 1.0 1.0 7 Q9Y4G8 1 +Regulation of membrane repolarization 0.3714575628652083 0.2463412237625018 0.8054181009938137 1.0 1.0 6 O75844 1 +Actin mediated cell contraction 0.3169520971784746 0.2455591215116771 0.806023536695692 1.0 1.0 18 P16615,Q99996,P05023,P09493 4 +Autophagosome maturation 0.3217907867214382 0.2439276418455759 0.8072868605855019 1.0 1.0 17 O43633,P16615,O95721,Q9UMX0 4 +Vasculature development 0.2676926152801538 0.2431187944424227 0.8079133720779461 1.0 1.0 110 P55011,P57105,Q9Y4G8,Q9H2J4,O95470,Q5JRA6,P52789,P31749,Q96AY3,O94788,Q9NZ08,Q15363,P06576,Q9H6U6,Q86UE4,Q15648,P09601,Q92990,Q9BXJ9,P32929,Q8NCM8,O75116,Q96PU8,P35579,P42785 25 +Positive regulation of oxidative stress induced cell death 0.4180672187862831 0.2418984586197675 0.8088588445153253 1.0 1.0 4 P23246 1 +Cellular sodium ion homeostasis 0.3909207972060313 0.2402673003142364 0.8101230431674806 1.0 1.0 5 P55011,P05023 2 +Cellular response to gamma radiation 0.3560237146275342 0.2399992061028489 0.8103308720599198 1.0 1.0 9 O75844 1 +Organic anion transport 0.3214273977146288 0.2388255098875091 0.8112408884962166 1.0 1.0 49 P55011,Q9H2D1,O95563,Q8TB61,Q96QD8,Q9Y6M7,P30825,Q9UBX3,P14174 9 +Positive regulation of production of mirnas involved in gene silencing by mirna 0.4166419899318851 0.238131934777022 0.8117787666842533 1.0 1.0 4 P04637,P00533,Q02750 3 +Purine nucleoside monophosphate metabolic process 0.3100992016677498 0.2377379819181337 0.8120843227777022 1.0 1.0 25 P00813,Q14168 2 +Negative regulation of innate immune response 0.3310798510153309 0.2373471364717642 0.8123874969940283 1.0 1.0 14 Q9Y4E8,Q9Y3Z3,Q14166,Q7Z739,P19474,Q9UIV1 6 +Membrane docking 0.3163283241466977 0.237050762049427 0.8126174099002079 1.0 1.0 31 O43752,O95721,O43865,Q13277,O60763,P16615,P15311,Q13190 8 +Regulation of steroid metabolic process 0.3282331404462723 0.2366007921464623 0.8129665056060107 1.0 1.0 15 P16435,P30536 2 +Positive regulation of neurotransmitter transport 0.4160497482972992 0.2365751180571381 0.8129864252026497 1.0 1.0 4 P20337,Q00535,Q15042 3 +Hair follicle maturation 0.3895142180094638 0.2361314137690702 0.8133306984029645 1.0 1.0 5 P18074,P35222,Q5C9Z4,Q08J23 4 +Regulation of cellular component size 0.2565085222725719 0.2348049638224068 0.814360114869793 1.0 1.0 93 P55011,Q13813,Q9NQC3,Q13439,P50570,Q9NUQ9,P15311,O95429,Q7L576,Q8N0X7,Q01082,Q9P2J5,P49841,Q9UQB8,P35612,Q4KMQ2,P16220,P62993,Q13045,Q9BPX3,P35609,P07196,P35611,Q9UEY8,P54105,O15020,O15144 27 +Negative regulation of protein catabolic process 0.321033726307036 0.2304651273048225 0.8177303585536488 1.0 1.0 46 Q96KB5,Q16850,Q8N163,Q8IXJ6,Q9H2J4,P46379,P49069,O15372,Q96QK1,Q13257,Q96JB5,Q96HY6,O15294 13 +Regulation of glycoprotein metabolic process 0.3268580967179926 0.229527038615383 0.8184593077278701 1.0 1.0 15 Q99805,Q08379 2 +Synaptic transmission glutamatergic 0.362477771191466 0.2281075682246526 0.8195626165958019 1.0 1.0 7 Q8NBU5,Q00535,P54920,Q15042,P51790,Q9BQT9 6 +Cell cell adhesion mediated by cadherin 0.3624777711914659 0.2281075682246526 0.8195626165958019 1.0 1.0 7 Q07157,P49593,O75955,O60716,P55196,P41440 6 +Embryonic skeletal joint morphogenesis 0.5969221663214028 0.2262491719080509 0.8210076283059105 1.0 1.0 2 O95747 1 +Nephron tubule formation 0.5969221663214028 0.2262491719080509 0.8210076283059105 1.0 1.0 2 O95747 1 +Limb joint morphogenesis 0.5969221663214028 0.2262491719080509 0.8210076283059105 1.0 1.0 2 O95747 1 +Embryonic skeletal joint development 0.5969221663214028 0.2262491719080509 0.8210076283059105 1.0 1.0 2 O95747 1 +Epidermis morphogenesis 0.5969221663214028 0.2262491719080509 0.8210076283059105 1.0 1.0 2 O60568 1 +Regulation of core promoter binding 0.5969221663214026 0.2262491719080507 0.8210076283059107 1.0 1.0 2 Q00403 1 +Positive regulation of neuroblast proliferation 0.5969221663214026 0.2262491719080507 0.8210076283059107 1.0 1.0 2 O60341 1 +Hippo signaling 0.3618850029638429 0.2260822096291558 0.8211374810536081 1.0 1.0 7 P35240,Q8TD19,Q13043,Q4VCS5,Q01085,Q16539 6 +Cytoplasmic sequestering of transcription factor 0.3651096681502247 0.2256383332871031 0.8214827239522045 1.0 1.0 6 Q9UN86 1 +Antigen processing and presentation of exogenous antigen 0.3574830998485503 0.2256262299242649 0.8214921383200695 1.0 1.0 8 Q03518,Q06323,P50570 3 +Gamete generation 0.2613703172934413 0.2241357153377125 0.8226517025306277 1.0 1.0 102 P46379,Q07666,P50570,O95470,Q14997,Q9Y508,P41208,Q9H6S0,Q15019,P31749,O94901,Q9Y2W6,Q9BY67,Q9BTX1,Q9H2U1,Q99417,Q08J23,Q96PU8,Q9BPZ3,Q8IXJ6,Q15067,Q8NB90,A0AVF1,P26583,P43246,O75718,Q9BXW9,Q8N2A8,Q14141 29 +Centromeric sister chromatid cohesion 0.3641481481481518 0.22256070140393 0.8238774250197061 1.0 1.0 6 Q9GZZ1,P35222,P30153,P41227,P49711 5 +Regulation of protein localization to membrane 0.3176027791902782 0.2223586593853188 0.824034691261978 1.0 1.0 53 Q13501,P31749,P33176,P31751,Q4V328,Q13277,Q9GZY8,P15311,O14737,O00264,Q01082,Q9HD26 12 +Regulation of cytoplasmic translation 0.3220263647777692 0.2221195558326162 0.8242208147314063 1.0 1.0 16 P67809,Q06787,O60506,Q9H2U1,Q9H074,Q9Y5A9 6 +Somite development 0.3383288986098948 0.221075113215737 0.8250339476241706 1.0 1.0 11 O94788 1 +Trophoblast cell migration 0.4707197883770924 0.2208508065808979 0.8252086022315988 1.0 1.0 3 Q07021 1 +Cardiac neural crest cell differentiation involved in heart development 0.4706927175843794 0.2207912698045839 0.8252549615303726 1.0 1.0 3 P28482,P27361 2 +Establishment of golgi localization 0.4706927175843733 0.2207912698045708 0.8252549615303828 1.0 1.0 3 Q9Y678,P63104 2 +Striated muscle cell development 0.3303435127024164 0.2197094803662014 0.8260974208059653 1.0 1.0 12 P09493 1 +Negative regulation of response to biotic stimulus 0.3043630843338644 0.2178081805139031 0.8275785704548855 1.0 1.0 23 Q9Y4E8,Q9Y3Z3,Q8IXJ6,Q92890,Q14166,O43657,Q7Z739,P19474,Q07021,Q9Y5A9,Q9UIV1 11 +Negative regulation of mrna splicing via spliceosome 0.3209400463912338 0.2163977040155108 0.828677755804335 1.0 1.0 16 P22626,P98175,P38159,P61978,Q15287,Q07021 6 +Receptor signaling pathway via stat 0.3209266819044157 0.2163275042022441 0.8287324713523123 1.0 1.0 16 Q8WXW3,O14964,Q9NX40 3 +Regulation of mitotic centrosome separation 0.4686204854943904 0.2162614996270572 0.8287839177812795 1.0 1.0 3 P43487,Q9UNZ2 2 +Cellular response to thyroid hormone stimulus 0.4080733643880773 0.2160905548491911 0.8289171619335536 1.0 1.0 4 P35241,Q15648 2 +Transcription coupled nucleotide excision repair 0.4080544862303675 0.2160431508192632 0.8289541122218418 1.0 1.0 4 P18074,P19447,Q93009 3 +Neurotrophin signaling pathway 0.3586479970799623 0.2151305214853804 0.82966555826796 1.0 1.0 7 Q9Y4G8 1 +Positive regulation of immune system process 0.2720377274673334 0.2121850494293344 0.8319626700173193 1.0 1.0 121 P12956,P46379,Q5RKV6,Q07666,P30825,Q5JRA6,Q9NUQ9,P10909,P31749,O00429,Q9NUD5,P15311,Q07021,Q15233,P00813,Q15648,P09601,Q9HCL2,Q9H2U1,Q8WXF1,Q4KMQ2,P16220,P14174,P49770,P26583,P23246,P09429 27 +Androgen metabolic process 0.3805833939485048 0.2105816300768999 0.8332137479564827 1.0 1.0 5 O95470 1 +Late endosome to vacuole transport 0.3282041686397615 0.2099215160456732 0.8337289289912413 1.0 1.0 12 O43633,Q9H3S7,Q9BRG1 3 +Carboxylic acid transport 0.3167170251723416 0.208022144559259 0.8352116766985538 1.0 1.0 38 P55011,Q9H2D1,O95563,Q96QD8,P07602,P30825,Q9UBX3,P14174 8 +Fatty acid elongation 0.5877478543947974 0.2079747687586354 0.8352486682124154 1.0 1.0 2 Q9NZ01 1 +Nadh dehydrogenase complex assembly 0.3110304592125319 0.20746533504258 0.8356464623284969 1.0 1.0 30 Q7L592,O95168,O75306,O43674,P56556,P03886,Q9H061,O96000,O43676,Q86Y39,Q96CU9 11 +Interstrand cross link repair 0.4044431628293471 0.2070698657019282 0.8359552957293741 1.0 1.0 4 Q9H1E3 1 +Purine nucleotide transport 0.3415570795135022 0.2065402026294321 0.8363689644936154 1.0 1.0 10 Q8TB61 1 +Regulation of animal organ morphogenesis 0.3414417086917891 0.2060797591259864 0.8367286093008124 1.0 1.0 10 Q93074,O95487,Q13308,P61586,P35222,O14641,P63000,Q9Y5V3,P60953 9 +Positive regulation of anion transport 0.3519926936286233 0.20602071440718 0.8367747306246811 1.0 1.0 8 P14174 1 +Negative regulation of response to endoplasmic reticulum stress 0.3222171583000921 0.2059990495544008 0.8367916537300781 1.0 1.0 15 Q96HY6,P10909 2 +Regulation of torc2 signaling 0.5865640722107194 0.2056895389434631 0.8370334305532758 1.0 1.0 2 Q9NWS0 1 +Mammary gland duct morphogenesis 0.4035586347706563 0.2049009665414941 0.8376495000501272 1.0 1.0 4 Q9Y297 1 +Plasma membrane raft organization 0.463291888691538 0.2048659148663464 0.8376768863652511 1.0 1.0 3 O75955,P41440 2 +Plasma membrane raft assembly 0.463291888691538 0.2048659148663464 0.8376768863652511 1.0 1.0 3 O75955,P41440 2 +Purine nucleotide catabolic process 0.341067751507434 0.2045891916314375 0.8378931006150978 1.0 1.0 10 P00813 1 +Positive regulation of cysteine type endopeptidase activity 0.3111402468316034 0.2019919729127132 0.8399229995303741 1.0 1.0 31 Q96A26,Q9NR28,O14737,O95831,Q9BXK5 5 +Pyrimidine nucleobase biosynthetic process 0.3546312291747936 0.2017998200874869 0.8400732222048015 1.0 1.0 7 P17812,Q9NRF8 2 +Cellular response to retinoic acid 0.3254961126989483 0.2017458694240184 0.8401154012060423 1.0 1.0 13 O43464,O94788 2 +Positive regulation of protein k63 linked ubiquitination 0.584196507842563 0.2011691876539259 0.8405662836529029 1.0 1.0 2 P61088 1 +Positive regulation of nlrp3 inflammasome complex assembly 0.5841965078425632 0.2011691876539253 0.8405662836529033 1.0 1.0 2 Q9H6R0 1 +Microtubule organizing center organization 0.3169892444418928 0.2002435221597066 0.8412901306388565 1.0 1.0 47 O43633,Q14203,O75116,Q9BV73,Q66GS9,Q9H6U6,Q08379,Q15154,P06493,O94927,Q9H6D7,Q7Z4H7,Q8IWJ2,P41208 14 +Neuromuscular process controlling balance 0.3250096570559593 0.199483631857394 0.8418844459369159 1.0 1.0 13 Q8IZL8 1 +Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 0.3131633013137782 0.1993026425519264 0.8420260121830618 1.0 1.0 34 Q9BY67,Q9NUQ9,P10909,Q5RKV6,P09429,Q07021,Q9UQ84,P00813 8 +Multivesicular body sorting pathway 0.3249686698923319 0.1992932834140801 0.8420333328540157 1.0 1.0 13 O43633,Q9H3S7,Q9BRG1 3 +Endosome transport via multivesicular body sorting pathway 0.3249686698923319 0.1992932834140801 0.8420333328540157 1.0 1.0 13 O43633,Q9H3S7,Q9BRG1 3 +Stress granule disassembly 0.4602023306118923 0.198426341744751 0.8427115094367368 1.0 1.0 3 P33176 1 +Positive regulation of lymphocyte apoptotic process 0.4600355239787025 0.1980821871601167 0.8429807612892539 1.0 1.0 3 Q07812,Q9Y255 2 +Respiratory electron transport chain 0.3136961625261961 0.194962358003417 0.845422416070579 1.0 1.0 54 Q9UDW1,P00403,P56556,P03886,O14949,P43304,O96000,P13073,O43676 9 +Keratinocyte differentiation 0.3021225155451053 0.1949455637888866 0.8454355636751196 1.0 1.0 24 Q16739 1 +Multicellular organismal signaling 0.3019967275128156 0.1941562515273477 0.8460535371933857 1.0 1.0 24 Q7Z406,P0DP25,P16615,O75844,Q99996 5 +Positive regulation of protein import 0.3078939983779786 0.19391370087756 0.8462434555756184 1.0 1.0 18 P12270,O00410,O75312,O14737 4 +Organelle localization 0.3089197622054607 0.1937145485886838 0.8463993995011765 1.0 1.0 191 O43633,O75153,Q9H0B6,Q9Y2T2,Q9BVK6,Q15154,O60313,Q9BZG1,Q13190,P50570,P42858,Q8WXH0,P42704,O75381,Q13561,Q96GA3,Q9NR31,O94901,O00429,O43752,P33176,O95721,O60271,Q13277,Q96DB5,Q8TD16,Q9UNH7,Q92572,P15311,Q8WXW3,Q99567,Q15363,O43707,Q13257,Q99584,P09601,Q14203,O43865,O00159,Q9NVT9,Q99996,P49755,P07196,Q96D46,O95772,Q14849,Q86YV9,Q15058,O14964,O60763,P16615,Q8WUX9,P35579,O15027,Q8IWA4 55 +Vesicle targeting rough er to cis golgi 0.3314258709411814 0.191731276333523 0.8479527055027427 1.0 1.0 11 Q15363,P49755,Q9NR31 3 +Microtubule nucleation 0.3216053297484645 0.1911423204616626 0.8484140919028118 1.0 1.0 14 Q99996,Q08379,Q96P70,Q9BSJ2 4 +Positive regulation of protein localization to cell periphery 0.301505741589923 0.1910806313002564 0.8484624220290835 1.0 1.0 24 Q13501,P33176,P31749,Q13277,P15311,O00264,Q01082 7 +Production of sirna involved in rna interference 0.397690257625102 0.1908031001266563 0.8486798597590204 1.0 1.0 4 O75569,Q9UPY3,Q99598 3 +Cell proliferation involved in kidney development 0.5785735424681921 0.1907017505375358 0.8487592671319408 1.0 1.0 2 O95747 1 +Cell proliferation involved in metanephros development 0.5785735424681921 0.1907017505375358 0.8487592671319408 1.0 1.0 2 O95747 1 +Negative regulation of kidney development 0.5785735424681921 0.1907017505375358 0.8487592671319408 1.0 1.0 2 O95747 1 +Mesenchymal cell differentiation involved in kidney development 0.5785735424681921 0.1907017505375358 0.8487592671319408 1.0 1.0 2 O95747 1 +Metanephric mesenchymal cell differentiation 0.5785735424681921 0.1907017505375358 0.8487592671319408 1.0 1.0 2 O95747 1 +Metanephric renal vesicle morphogenesis 0.5785735424681919 0.1907017505375356 0.848759267131941 1.0 1.0 2 P35222 1 +Regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis 0.5785735424681919 0.1907017505375356 0.848759267131941 1.0 1.0 2 P35222 1 +Metanephric nephron morphogenesis 0.5785735424681919 0.1907017505375356 0.848759267131941 1.0 1.0 2 P35222 1 +Mesenchymal to epithelial transition involved in metanephros morphogenesis 0.5785735424681919 0.1907017505375356 0.848759267131941 1.0 1.0 2 P35222 1 +Positive regulation of mesenchymal cell proliferation 0.5785735424681919 0.1907017505375356 0.848759267131941 1.0 1.0 2 P35222 1 +Positive regulation of mrna splicing via spliceosome 0.3119826394368319 0.1903669978219466 0.8490215566870847 1.0 1.0 17 Q14011,P98179 2 +Ketone biosynthetic process 0.3472975288903199 0.1897044341494609 0.8495407459606865 1.0 1.0 8 Q8NI60,Q14849 2 +Cellular response to estradiol stimulus 0.3500192390378994 0.1868562252937554 0.8517733617663763 1.0 1.0 7 Q14103,P00533,P20248,O95831 4 +Protein localization to cell surface 0.2964022580086609 0.1866809218912889 0.8519108152552588 1.0 1.0 21 P35609,P31749,Q13277,Q9UJY4,Q92544,Q9HD26 6 +Neuronal action potential 0.3717970106982682 0.1866786129186687 0.85191262572557 1.0 1.0 5 Q7Z406 1 +Platelet derived growth factor receptor signaling pathway 0.3364751660576056 0.1865223332906294 0.8520351667256092 1.0 1.0 10 O95470 1 +Negative regulation of cell junction assembly 0.3455106601223562 0.1836065766375866 0.8543221034276154 1.0 1.0 8 Q9H6U6,Q15375,Q13464,O75116 4 +Ribosomal small subunit export from nucleus 0.3489162039038936 0.1833407185396659 0.8545306870557106 1.0 1.0 7 Q99567 1 +Neurotransmitter receptor transport endosome to postsynaptic membrane 0.3944256067754785 0.1831818819940751 0.854655309902741 1.0 1.0 4 Q4V328 1 +Tissue morphogenesis 0.2559397709076149 0.1829831633171872 0.8548112292987182 1.0 1.0 87 P62942,Q92990,Q96A65,O94788,O15031,Q9UNS1,Q9Y2G5,O60313,Q15363,P15311,O14641,P09493,P49815,Q9Y297,Q8N3R9,Q5T9L3 16 +Membrane repolarization 0.3408325785193665 0.1827211911235823 0.8550167875699577 1.0 1.0 9 O75844,Q99996 2 +Cytokine production 0.2563959473634743 0.1822464022931003 0.8553893589366943 1.0 1.0 99 P31483,Q9NUQ9,P10909,P30536,Q9NUD5,Q8WXW3,P15311,P19474,Q07021,Q01082,Q9BY67,Q9Y6M1,P09601,Q92990,Q9HCL2,Q9BWS9,Q9H2U1,O75116,P49755,P14174,Q96RT1,P26583,P09429 23 +Cellular component disassembly involved in execution phase of apoptosis 0.3449374054946347 0.1816635347902465 0.855846784752841 1.0 1.0 8 Q96JB5,O95831 2 +Response to insulin 0.2969433896407937 0.178754429543787 0.8581305288089531 1.0 1.0 68 Q16836,P31751,Q9H1E3,Q8TBX8,Q86YS7,Q5VZ89,P11802,Q9Y5X3,P31749,Q6ZWJ1,Q92572,Q7L576,P43490,O15294,P49841,Q9UQB8,P25054,O00159,P49815,P62993,O60763,Q9BSK2 22 +Establishment of endothelial barrier 0.3051416899777091 0.1787097458023596 0.8581656163382514 1.0 1.0 18 P35611,Q9UDY2,Q9Y4G8,P35241,P15311,Q9H0U4,O75116,P55196 8 +Rig i signaling pathway 0.319944013444098 0.1762702301003549 0.8600816487506515 1.0 1.0 13 Q9Y4E8,Q14258,Q92890,Q9NUD5,Q07021 5 +Intra golgi vesicle mediated transport 0.3128390807598643 0.1747382446353444 0.8612853151933937 1.0 1.0 16 Q8TBA6 1 +Protein localization to early endosome 0.348286748189622 0.1741027798447817 0.8617846885663143 1.0 1.0 6 P15311,O75116 2 +Regulation of cell shape 0.3068268023959073 0.1735492503945482 0.8622197189391356 1.0 1.0 31 Q7Z406,Q9UQB8,O15031,P35580,Q9UEE9,O75844,P35579,P09493,Q7L576 9 +Negative regulation of cholesterol metabolic process 0.5688073394495476 0.1734219138790937 0.8623198012877449 1.0 1.0 2 O94905 1 +Negative regulation of alcohol biosynthetic process 0.5688073394495476 0.1734219138790937 0.8623198012877449 1.0 1.0 2 O94905 1 +Torc2 signaling 0.3896949955581802 0.1724230429581789 0.8631049578005365 1.0 1.0 4 Q96A49,Q9NWS0,Q9Y4R8 3 +Fatty acid alpha oxidation 0.389451017644966 0.1718773575531651 0.8635339477187514 1.0 1.0 4 O43808 1 +Semi lunar valve development 0.3893988747408803 0.1717608512057548 0.8636255442589511 1.0 1.0 4 Q13464,O94813,O75116 3 +Clathrin coat assembly 0.3449911084765878 0.1710173726845537 0.8642101054049152 1.0 1.0 7 Q00610,P09496,O00443,P63010,P42566,P53680 6 +Positive regulation of striated muscle cell differentiation 0.3652251184833992 0.1696269927253614 0.8653034930500352 1.0 1.0 5 Q9UGN5,Q96TA1,P42345,Q16539 4 +Positive regulation of leukocyte migration 0.2980627575276412 0.1693096846632479 0.8655530586961153 1.0 1.0 19 Q5JRA6,O00429,Q4KMQ2,P09429 4 +Camera type eye development 0.3086578222625859 0.1689201824119778 0.8658594240498008 1.0 1.0 34 Q15555,O94788,P08670,P48681,Q15293 5 +Positive regulation of organic acid transport 0.3442833891681349 0.1688266755833194 0.8659329754141549 1.0 1.0 7 P14174 1 +Positive chemotaxis 0.3367528766375763 0.1681272880109099 0.8664831421764241 1.0 1.0 9 P49815,P09429,P14174 3 +Negative regulation of protein containing complex disassembly 0.3027090763905061 0.1671402983133141 0.8672596585004055 1.0 1.0 28 Q13045,Q9BPX3,Q13813,P35611,P35241,P35612,P25054,Q9NYL9,Q9UEY8,O15020,Q01082 11 +Calcium ion regulated exocytosis 0.3314003549323827 0.1670854842341505 0.8673027873599495 1.0 1.0 10 P16615,P35579 2 +Mitochondrial electron transport nadh to ubiquinone 0.2994788155663949 0.1620470754826739 0.8712687828635284 1.0 1.0 26 O43676,O96000,P56556,P03886 4 +Response to chemokine 0.3440000000000024 0.1617819462549839 0.8714775705432016 1.0 1.0 6 P55011,Q96T37,Q9H4A3,O95747,O94813 5 +Regulation of nadp metabolic process 0.3619668246445408 0.1614412550757174 0.8717458759534666 1.0 1.0 5 Q9NQ88,P04637,P18669,P48163 4 +Regulation of hippo signaling 0.3616706161137342 0.1607060133289028 0.8723249530480428 1.0 1.0 5 P35240,Q8TD19,Q16539,Q01085 4 +Regulation of response to oxidative stress 0.2918957700002792 0.1595959884950822 0.8731993391939761 1.0 1.0 21 O43464,P31749,P00374,P23246,Q9UMX0,Q15233 6 +Axis elongation 0.3607819905213211 0.1585092437341679 0.8740555372994785 1.0 1.0 5 Q13308,Q93074,Q13263,Q15648 4 +Regulation of body fluid levels 0.3079476666774692 0.1582728852679787 0.8742417732381951 1.0 1.0 56 P52789,P16949,Q13505,Q86YV9,P61201,P00403,P38435,P35579,P16220,P12814,Q16739,P00813,Q15648 13 +Positive regulation of interleukin 1 production 0.3405514894328081 0.1574351197786245 0.874901936975754 1.0 1.0 7 P49755,P09429 2 +Histone h2b ubiquitination 0.3423028226117322 0.15699827076507 0.8752462109315713 1.0 1.0 6 Q5VTR2 1 +Positive regulation of nik nf kappab signaling 0.3156175771971479 0.1569568373503304 0.8752788651923453 1.0 1.0 13 P05067,P35232,Q13418,P19525,P00533,P61586,Q53EL6,Q99623,P23396,Q9NYB0,O43707,O00571 12 +Cardiac septum morphogenesis 0.3370886451230318 0.1557203654437607 0.8762534436950882 1.0 1.0 8 P04637,P20248,Q96T37,Q06330,P98164,O96028,O94813 7 +Establishment of lymphocyte polarity 0.3818814739413033 0.1553992286993201 0.8765065921881099 1.0 1.0 4 P35579 1 +Regulation of type i interferon mediated signaling pathway 0.3149638497408812 0.1540808793719202 0.8775459642862387 1.0 1.0 13 Q9Y3Z3,Q14166,Q7Z739,Q16543,Q9UIV1 5 +Pyrimidine nucleoside triphosphate biosynthetic process 0.3217455489828523 0.1523909271073942 0.8788786126227539 1.0 1.0 11 P17812,Q9NRF8,Q13232 3 +Positive regulation of cell division 0.3110675632174058 0.151797989894011 0.8793462675947321 1.0 1.0 15 Q8IXJ6 1 +Regulation of protein localization to plasma membrane 0.3060198390839641 0.1514800484840137 0.8795970482234186 1.0 1.0 34 Q13501,P33176,P31749,Q4V328,Q13277,P15311,O00264,Q01082,Q9HD26 9 +Sodium ion export across plasma membrane 0.4339232567472304 0.1487147639325831 0.8817787108564861 1.0 1.0 3 P05023 1 +Middle ear morphogenesis 0.3784424045010285 0.1482040716230031 0.8821817186144605 1.0 1.0 4 O75569,O95747,P54802 3 +Positive regulation of focal adhesion assembly 0.3369887374036772 0.146814510306089 0.8832784312270177 1.0 1.0 7 Q9Y2S7,P49593,Q96AC1,P63000,Q13464,P60903 6 +Regulation of aspartic type peptidase activity 0.3759877922547884 0.1431806848621957 0.8861474838872629 1.0 1.0 4 P49755 1 +Regulation of aspartic type endopeptidase activity involved in amyloid precursor protein catabolic process 0.3759877922547884 0.1431806848621957 0.8861474838872629 1.0 1.0 4 P49755 1 +Negative regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway 0.3371659675536304 0.1428503561900603 0.8864083663726363 1.0 1.0 6 O60313,O95881 2 +Xenobiotic transmembrane transport 0.5495708789582785 0.1427266413390029 0.8865060753750544 1.0 1.0 2 P41440 1 +Striated muscle cell proliferation 0.3328101110331541 0.1421086175679166 0.8869942114272271 1.0 1.0 8 Q8NDZ4 1 +Developmental growth 0.2619312869973504 0.1415488889318419 0.8874363410152966 1.0 1.0 113 Q7Z4V5,Q08209,Q9Y4W6,Q9NQC3,Q13439,P50542,O95470,P31749,O75312,O60271,Q8NDZ4,Q15363,P15311,Q9BRT9,Q7L576,Q8N0X7,Q15648,O43464,Q9HCL2,P61201,Q05086,P16435,P16220,P06493,P07602,O75844,O15020 27 +Regulation of oxidative stress induced cell death 0.2927088204431898 0.139449276551466 0.8890951356552284 1.0 1.0 19 O43464,P31749,P23246,Q9UMX0,Q15233 5 +Regulation of action potential 0.311947791592739 0.1391019676968157 0.8893695733472669 1.0 1.0 12 P16615,P0DP25 2 +Plasma membrane repair 0.3236858205701147 0.138643024831162 0.889732242712729 1.0 1.0 10 O43633,P35579 2 +Pyrimidine ribonucleotide biosynthetic process 0.3180621892120339 0.1380070882344422 0.8902348155543478 1.0 1.0 11 P17812,Q9NRF8,Q13232 3 +Acid secretion 0.4274718768502147 0.1379091761318963 0.8903121982037281 1.0 1.0 3 Q7L0J3,P80404 2 +Estrogen biosynthetic process 0.5460195324060442 0.1375411284074787 0.8906030858649459 1.0 1.0 2 Q8NBQ5 1 +Positive regulation of oxidative stress induced intrinsic apoptotic signaling pathway 0.4269029160029503 0.1369827138908291 0.8910444586187216 1.0 1.0 3 P23246 1 +Oligodendrocyte differentiation 0.2896224362157775 0.1369509107093219 0.8910695969802125 1.0 1.0 22 Q96P11 1 +Positive regulation of cell adhesion 0.2939440915689114 0.1363989374746283 0.8915059136011847 1.0 1.0 67 Q9NUQ9,Q9H3S7,Q08209,P31749,Q9HCL2,P49841,Q13277,Q07021,P09429,P30825,P50570,O95429,P09493,P00813,O15144 15 +Negative regulation of viral life cycle 0.4257475371296992 0.1351145680031176 0.8925212921994929 1.0 1.0 3 Q12899 1 +Negative regulation of viral entry into host cell 0.4257475371296992 0.1351145680031176 0.8925212921994929 1.0 1.0 3 Q12899 1 +Vesicle cytoskeletal trafficking 0.291684601941341 0.1338542255301148 0.8935178471910796 1.0 1.0 19 P33176,Q9Y2T2,Q92572,O43707,P42858 5 +Positive regulation of neurogenesis 0.3081517391504744 0.1336317476444807 0.8936937783468919 1.0 1.0 46 P55209,P07196,P30536,Q9UQB8,Q13439,Q7L576 6 +Regulation of dna damage response signal transduction by p53 class mediator 0.3221452766563571 0.1331280040454458 0.8940921482378219 1.0 1.0 10 O75844 1 +Escrt complex disassembly 0.3296966840787588 0.1324450297598782 0.8946322997662237 1.0 1.0 8 O43633,Q8WUX9,P53990,Q9NZZ3 4 +Negative regulation of cyclin dependent protein serine threonine kinase activity 0.3331123729554633 0.1320417863967873 0.8949512403218851 1.0 1.0 6 O00410,P25054 2 +Mitochondrial dna metabolic process 0.3330370370370406 0.1318439120074643 0.8951077529378688 1.0 1.0 6 Q13472,P04637,Q9BQP7,P09874,P36776 5 +Regulation of insulin secretion 0.2916495627041712 0.1312019030090876 0.8956155905892642 1.0 1.0 24 Q16836,O95563,Q08209,Q6ZWJ1,O43768 5 +Organ growth 0.2912963909350604 0.1291250658844405 0.8972586883318456 1.0 1.0 24 Q8NDZ4,O75844,Q05086,P31749 4 +Endothelial cell migration 0.3054453272593295 0.1268089692630934 0.8990915966067041 1.0 1.0 39 Q5JRA6,P57105,P09601,P31749,P35579,P06576,P09429,Q9H6U6,P42785,Q8WTV0 10 +Sensory organ morphogenesis 0.2890419846196155 0.1246264664868505 0.9008192745204572 1.0 1.0 23 Q8IZL8,O14641 2 +Aminophospholipid translocation 0.5362533293873997 0.1240436919758761 0.9012806809891576 1.0 1.0 2 Q9NV96 1 +Regulation of triglyceride metabolic process 0.3657387270540342 0.1232207104249405 0.9019323259940072 1.0 1.0 4 Q8WTV0,Q96N66 2 +Cochlea development 0.3285878347578926 0.1227786700724049 0.9022823652648776 1.0 1.0 7 P33993,P20248,O14641 3 +Secondary alcohol metabolic process 0.3062589608043251 0.1226845804210707 0.9023568746570167 1.0 1.0 43 P48449,Q16850,Q15125,Q14849,Q15800,Q15392,P53396,Q9BQE5,P16435,Q14739,Q8WTV0 11 +Negative regulation of organ growth 0.4177027827116613 0.1225963056341594 0.9024267800525652 1.0 1.0 3 Q13043,P11413 2 +Cell cell adhesion involved in gastrulation 0.534181710565263 0.1213230463208415 0.9034351665245212 1.0 1.0 2 Q9NPQ8 1 +Glycosyl compound metabolic process 0.2951894181828822 0.1207098354158048 0.9039208684302864 1.0 1.0 28 Q9NUJ1,Q13126,O60725,P00813 4 +Positive regulation of glucokinase activity 0.533589819473224 0.120554795769331 0.9040436753589544 1.0 1.0 2 P49792 1 +Neuron intrinsic apoptotic signaling pathway in response to oxidative stress 0.3639699069811982 0.1199422007726882 0.904528934377982 1.0 1.0 4 Q15233 1 +Positive regulation of lymphocyte migration 0.3438981042653983 0.1193621997140696 0.9049884074042744 1.0 1.0 5 P78536,O95747,P05067,Q9H4A3 4 +Positive regulation of t cell migration 0.3438981042653983 0.1193621997140696 0.9049884074042744 1.0 1.0 5 P78536,O95747,P05067,Q9H4A3 4 +Establishment of epithelial cell apical basal polarity 0.3438981042653954 0.1193621997140632 0.9049884074042795 1.0 1.0 5 P26038,Q13308,P15311,P60953 4 +Citrulline metabolic process 0.4153345174659604 0.1190735652311122 0.905217073608096 1.0 1.0 3 Q05682,P27708 2 +Citrulline biosynthetic process 0.4153345174659604 0.1190735652311122 0.905217073608096 1.0 1.0 3 Q05682,P27708 2 +Lytic vacuole organization 0.2878118239238144 0.117531092644062 0.906439206413982 1.0 1.0 23 Q9BZG1,Q8N511 2 +Regulation of nik nf kappab signaling 0.2885187388459133 0.1168061803236206 0.9070136460912036 1.0 1.0 19 Q12959,P05067,Q9H000,P35232,Q13418,P19525,P61586,P00533,P27797,Q53EL6,O43657,P15311,Q9BZF9,Q99623,O43707,P23396,Q9NYB0,O00571 18 +Fibroblast migration 0.3008743349319258 0.1167142749238413 0.9070864778390104 1.0 1.0 16 O95470 1 +Regulation of synaptic transmission glutamatergic 0.3621557595498914 0.1166305981205877 0.907152789397348 1.0 1.0 4 Q8NBU5,Q00535,Q15042 3 +Heterophilic cell cell adhesion via plasma membrane cell adhesion molecules 0.3621557595498863 0.1166305981205782 0.9071527893973554 1.0 1.0 4 Q9BY67,Q13740,Q9P273 3 +Platelet morphogenesis 0.3269269084938943 0.1161639152902314 0.9075226345236812 1.0 1.0 6 P35579 1 +Endocrine pancreas development 0.3260504220062027 0.1158023454231637 0.9078091916446922 1.0 1.0 7 P49841,P31749 2 +Gland morphogenesis 0.3049802229725752 0.1157260144251689 0.9078696882404448 1.0 1.0 14 Q9Y297,P15311,Q15418 3 +Regulation of mitotic recombination 0.4129662522202478 0.1156243398424782 0.9079502718780132 1.0 1.0 3 P18074,Q92878 2 +Hippocampus development 0.2882873816710196 0.1155751416718596 0.9079892649284952 1.0 1.0 19 P07196 1 +Positive regulation of cell population proliferation 0.2757363121164065 0.1150211912254507 0.908428325349546 1.0 1.0 140 P31751,Q9H2J4,Q9NQC3,P30825,P07942,P43307,P55209,P30536,P31749,O94788,Q6ZWJ1,Q13277,Q86X55,P00813,P43490,Q15648,P09601,Q9HCL2,Q00577,P48681,O95684,Q96HY6,P14174,O60884,P06493,P26583,P09429,Q15058 28 +Positive regulation of osteoblast differentiation 0.3418246445497591 0.1148988535121697 0.908525293841983 1.0 1.0 5 Q13418,O00299,P35222,P20248 4 +Modification dependent macromolecule catabolic process 0.3078578928516867 0.1147863854019063 0.9086144405975204 1.0 1.0 201 O43633,O95155,Q9Y4E8,Q9Y4X5,Q9H2J4,Q96RU2,P46379,Q7L5D6,Q96A33,Q9Y5A7,Q9UBV2,Q9Y297,Q9BW61,Q9H9H4,Q9Y508,Q96KB5,Q9H3S7,P10909,P31749,Q13438,P33908,Q9UHG3,O15294,Q13501,Q8N163,Q92990,Q04323,P51665,Q05086,Q13868,O60826,Q9UMX0,O15372,Q96JB5,Q5VTR2,Q8IUR7,Q96HY6,O00231,Q9UBS8,Q8IXJ6,Q8WUX9,O75844,Q9BRG1,P49069,Q15058,Q9UJX4,Q96K76,O75150 48 +Digestive tract morphogenesis 0.3606751554634214 0.1139660742792197 0.9092646869825224 1.0 1.0 4 P35222,P00533,Q6KC79 3 +Morphogenesis of an epithelial fold 0.360675155463421 0.1139660742792192 0.9092646869825228 1.0 1.0 4 P35222,P00533,Q86V48 3 +Nuclear transcribed mrna catabolic process deadenylation independent decay 0.4117821195973915 0.1139272141204953 0.9092954922672364 1.0 1.0 3 Q6P2E9,Q9NPI6 2 +Antiviral innate immune response 0.3409360189573431 0.1130092857722672 0.9100231933959062 1.0 1.0 5 Q92667,Q9NVI7,P35232,Q9H078 4 +Amine catabolic process 0.3597867930115318 0.1123838453119519 0.9105190637508274 1.0 1.0 4 P49366,P21964,Q6QHF9 3 +Regulation of b cell activation 0.2921947131695935 0.1105411911643769 0.9119801841891636 1.0 1.0 18 Q5RKV6,P00813 2 +Retinol metabolic process 0.3223686230434581 0.110520936257607 0.9119962468465848 1.0 1.0 8 O94788 1 +Regulation of mrna binding 0.3240135003733714 0.1102986682157343 0.9121725134308674 1.0 1.0 7 Q06787,P60228,Q04637,Q86X55 4 +Notch receptor processing 0.524711453092638 0.1095105212597363 0.912797577200952 1.0 1.0 2 P78536 1 +Endosome to plasma membrane protein transport 0.3241612835900601 0.1093080663179005 0.912958148937792 1.0 1.0 6 Q4V328,Q96QK1 2 +Negative regulation of helicase activity 0.3574178264731956 0.1082249911635035 0.9138172213007836 1.0 1.0 4 P04637,P33993,P49736 3 +Regulation of protein tyrosine kinase activity 0.2989233437470608 0.1076775236610467 0.9142514993527582 1.0 1.0 16 O95684,O14641,Q9BRG1 3 +Maternal placenta development 0.3228858530416406 0.1072890306490787 0.9145596865852992 1.0 1.0 7 P31749 1 +Negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway 0.2952877539335138 0.105858741135971 0.915694429872878 1.0 1.0 17 Q9UNH7,P62942,Q8N0X7,Q92896 4 +Regulation of cell growth involved in cardiac muscle cell development 0.4055654233274086 0.1053162525716141 0.9161248670060786 1.0 1.0 3 O94826,P11413 2 +Retinal ganglion cell axon guidance 0.3367890995260561 0.1043765735977325 0.9168705126845852 1.0 1.0 5 Q13740,Q15375,P83731,O94813 4 +Abscission 0.3543968984432212 0.103048969005224 0.9179241061458668 1.0 1.0 4 Q8N0X7 1 +Regulation of genetic imprinting 0.5187925421722475 0.1026400359198276 0.918248666555783 1.0 1.0 2 Q6PD62 1 +Guanine nucleotide transport 0.518496596626228 0.1023066925168743 0.9185132433235004 1.0 1.0 2 P41440 1 +Cyclic gmp amp transmembrane import across plasma membrane 0.518496596626228 0.1023066925168743 0.9185132433235004 1.0 1.0 2 P41440 1 +Guanine nucleotide transmembrane transport 0.518496596626228 0.1023066925168743 0.9185132433235004 1.0 1.0 2 P41440 1 +Protein localization to basolateral plasma membrane 0.5182006510802086 0.1019743116984592 0.9187770650658468 1.0 1.0 2 P61026 1 +Negative regulation of insulin secretion involved in cellular response to glucose stimulus 0.5164249778040914 0.1000001854433137 0.9203441782215518 1.0 1.0 2 Q8N183 1 +Response to interferon alpha 0.3344194312796164 0.0995808837879748 0.9206770709052072 1.0 1.0 5 P12270,P19525,P55265,Q6L8Q7 4 +Myotube differentiation 0.2971116820230498 0.0993976509059678 0.9208225478344136 1.0 1.0 16 P35579,Q08209 2 +Positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 0.400828892835999 0.0990898752924794 0.921066910870176 1.0 1.0 3 Q9UII2,P49841 2 +Positive regulation of cell growth 0.3027818557487337 0.0971181835190088 0.922632540760925 1.0 1.0 44 Q7Z4V5,P31749,O95684,Q13868,Q15418,Q7L576,Q96K76 7 +Cell activation 0.2737803598098401 0.0971007713439722 0.9226463683139596 1.0 1.0 139 P12956,P62942,Q08209,P46379,Q5RKV6,P30825,P12814,Q9UQ84,P24390,Q9NUQ9,P0CG08,P10909,P31749,O96005,Q9UNH7,Q8WXW3,P00813,P09601,Q92990,Q9HCL2,P14174,P55327,P78318,P35579,P09429,Q15418 26 +Cell cycle dna replication initiation 0.3175375824351107 0.0935072236405806 0.9255006112051224 1.0 1.0 6 P33993,P33991 2 +Histone h3 k4 demethylation trimethyl h3 k4 specific 0.5102101213376811 0.0933601616515839 0.9256174386376969 1.0 1.0 2 Q9H6W3 1 +Alpha linolenic acid metabolic process 0.3470535978679235 0.0910606517375714 0.9274443980628976 1.0 1.0 4 P09110,O14734,O95864 3 +Actin filament depolymerization 0.2830151111789788 0.0904585906451917 0.9279227988751442 1.0 1.0 23 Q13045,P35609,Q13813,Q9BPX3,P35611,P35612,Q9UEY8,O15020,Q01082 9 +Positive regulation of epithelial cell migration 0.2964131245193621 0.0903166979649615 0.9280355513222802 1.0 1.0 34 P09601,P31749,Q15555,Q9NQC3,P06576,Q9H6U6,Q8WTV0 7 +Negative regulation of double strand break repair via nonhomologous end joining 0.5063628292394253 0.0894565126227214 0.9287191128673672 1.0 1.0 2 Q9UBB9 1 +Imp salvage 0.3927204342015106 0.0890918937636597 0.9290088796166228 1.0 1.0 3 Q01433 1 +Mitotic dna replication 0.3042145535901558 0.0870041030321923 0.9306682507291916 1.0 1.0 11 P25205,O75419,P33993,O75844,P33991 5 +Neural precursor cell proliferation 0.2939928001456978 0.0869387986221222 0.9307201594184932 1.0 1.0 32 O95456,O75306,P55209,Q8IXJ6,O15031,Q9UKA9,P48681,Q15154,Q92974,Q9UBD5,O60341,Q15058,Q8NCG7 13 +Regulation of osteoblast proliferation 0.3437962688776961 0.0860108779187393 0.9314577699447636 1.0 1.0 4 P19525,Q9Y251,P20248 3 +Osteoblast proliferation 0.3437962688776961 0.0860108779187393 0.9314577699447636 1.0 1.0 4 P19525,Q9Y251,P20248 3 +Morphogenesis of an endothelium 0.343796268877691 0.0860108779187317 0.9314577699447696 1.0 1.0 4 Q06330,P35222,P67870 3 +Cyclic nucleotide mediated signaling 0.3433729225665531 0.0853666023873246 0.9319699436463986 1.0 1.0 4 Q9Y4G8 1 +Energy derivation by oxidation of organic compounds 0.2676849303380055 0.0853607062293394 0.9319746309904442 1.0 1.0 130 P00846,P31751,O75964,Q9UDW1,Q13423,P22695,P03886,O14949,O43676,P14406 10 +Negative regulation of ossification 0.389283599763173 0.0851020337808845 0.9321802734515016 1.0 1.0 3 P22413,Q6W2J9 2 +Positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus 0.3892835997631707 0.0851020337808817 0.9321802734515036 1.0 1.0 3 P04637,Q9NXV6 2 +Protein localization to cell junction 0.2864468595752003 0.0847838696552944 0.9324332175117364 1.0 1.0 26 Q9UQB8,Q4V328,Q14168,P33176 4 +Establishment of protein localization 0.3882303301965996 0.0846317099100565 0.9325541886349592 1.0 1.0 566 P55011,O60830,O95563,P31751,P46379,Q96P70,Q8N8Q8,Q9Y282,Q9NS69,O43681,Q99595,O60725,Q13190,O00170,Q10713,P43307,P24390,Q9HD26,Q5JRA6,Q9Y5X3,Q16850,Q07820,Q8N4H5,P52789,P30536,P0CG08,O75312,O00410,Q6ZWJ1,P55786,Q9UNH7,Q53H12,P15311,P33908,P98194,Q9Y4P1,Q15648,P12270,O43731,Q13555,Q5HYI7,Q15629,Q9HD20,O60826,Q9P2W9,Q5T9L3,Q9BRT2,Q96RT1,Q9UID3,O14964,A0AVF1,Q14C86,O60763,P06493,Q92544,P49368,Q96QK1,Q8TEX9,O15260,Q9H4A5,P57105,Q9Y2T2,Q9BVK6,Q7L5D6,Q15388,O43768,Q15154,Q9NPA0,Q9BZG1,P49257,O14737,P50542,P50570,Q9H9H4,O75381,Q7Z7E8,Q8NFH4,P10909,P31749,O43752,Q9Y3A6,Q9UHB9,Q8TB36,Q92572,Q15005,P41214,O95429,O15126,A6NIH7,Q9Y5Y5,Q9BTX1,Q99584,Q9Y5M8,Q96KC8,P49841,Q66GS9,O60749,O43865,Q96C92,O95831,Q4J6C6,Q86YV9,P0DP25,P50402,Q567U6,Q14168,O43633,P40855,Q9Y5J7,Q9Y5J9,Q96A33,Q9UBV2,P41208,O95249,O14925,O00429,Q08379,Q32P28,Q8TD16,Q9H4A6,Q9C0E2,Q99567,Q8N1F7,Q03518,O43464,P49815,Q92973,O75298,Q4V328,P35580,Q9GZY8,Q5JRX3,P35579,Q9BRG1,Q96PC5,Q16836,O60220,Q08209,Q13439,Q96ED9,Q5VZ89,Q9H3S7,Q9NR31,Q8TCT9,P33176,Q13438,O95721,Q13277,Q15363,O95070,O43707,Q9H6U6,Q01082,P53365,Q13501,P78371,Q9UJY4,Q86UP2,Q15437,Q15276,P49755,Q96D46,Q96A65,Q8IUD2,Q8WUX9,P49069,O15027,Q15058,Q969Q5 169 +Response to type i interferon 0.295947369762964 0.0840766582215973 0.9329954829624896 1.0 1.0 15 Q9Y3Z3,Q14166,Q7Z739,Q16543,Q9UIV1 5 +Late endosome to golgi transport 0.3878034339846004 0.0834285116947745 0.9335108184778428 1.0 1.0 3 Q9UMY4,Q8IWJ2 2 +Regulation of response to external stimulus 0.27608089565593 0.0830713895829504 0.9337947750007702 1.0 1.0 145 P55011,P12956,Q9Y4E8,Q9UNW9,P80303,Q00013,P10586,Q96KB5,P28070,Q9NUQ9,O00429,Q9NZ08,Q13277,Q9NUD5,Q9UNH7,P19474,Q07021,Q15233,P00813,Q15648,Q9Y3Z3,Q96G23,Q8WXF1,Q4KMQ2,P14174,Q9UMX5,Q8IXJ6,O43657,P26583,O75844,P23246,P09429,Q9BXW9,Q96QK1 34 +Positive regulation of cell size 0.4992601361349588 0.0826554200863534 0.9341255331364452 1.0 1.0 2 O60341 1 +Transforming growth factor beta production 0.4992601361349587 0.0826554200863534 0.9341255331364452 1.0 1.0 2 Q9Y5K6 1 +Negative regulation of transforming growth factor beta production 0.4992601361349587 0.0826554200863534 0.9341255331364452 1.0 1.0 2 Q9Y5K6 1 +Cellular response to hormone stimulus 0.2737615843679194 0.0822776432877316 0.934425932204761 1.0 1.0 141 P31751,Q9H1E3,Q8TBX8,Q16739,Q5VZ89,Q9NZN8,Q9Y5X3,P05023,P31749,O15173,Q6ZWJ1,Q9P1Z2,Q86X55,Q7L576,Q9H6U6,P43490,Q15648,O15294,Q9UQB8,O43865,P25054,Q05086,O43251,P16435,O75116,P49815,O95831,Q8IZL8,Q96HY6,P35609,Q9UBS8,O60763,P42785 33 +Cd40 signaling pathway 0.3408350607047619 0.0815621322788994 0.9349949149888568 1.0 1.0 4 P35232,Q9BXW9,P05556 3 +Alcohol biosynthetic process 0.2949114337003735 0.0811084315373099 0.9353557203856752 1.0 1.0 34 P48449,Q16850,Q15125,P00374,Q15800,Q15392,P53396,P16435,Q14739 9 +Protein k48 linked ubiquitination 0.2973408847101974 0.0810007817601239 0.935441330794678 1.0 1.0 13 Q96J02,Q05086,P49427,Q15386,Q9Y297,P63208 6 +Tyrosine metabolic process 0.3842435438079825 0.0795129474479434 0.936624633645272 1.0 1.0 3 P16930 1 +Negative regulation of amine transport 0.4945250073986458 0.0784067203131372 0.9375045279535306 1.0 1.0 2 O75915 1 +Negative regulation of amino acid transport 0.4945250073986458 0.0784067203131372 0.9375045279535306 1.0 1.0 2 O75915 1 +Regulation of gamma aminobutyric acid secretion 0.4945250073986442 0.0784067203131358 0.9375045279535316 1.0 1.0 2 Q7L0J3 1 +Gamma aminobutyric acid transport 0.4945250073986442 0.0784067203131358 0.9375045279535316 1.0 1.0 2 Q7L0J3 1 +Gamma aminobutyric acid secretion 0.4945250073986442 0.0784067203131358 0.9375045279535316 1.0 1.0 2 Q7L0J3 1 +Membrane invagination 0.294592214586882 0.0783577563127492 0.9375434757462746 1.0 1.0 15 O43633,Q4KMQ2,P35579 3 +Lipid export from cell 0.3830409593693024 0.0782248408729451 0.937649202399258 1.0 1.0 3 P14174 1 +Negative regulation of jun kinase activity 0.4942290618526268 0.0781486061689249 0.9377098432552742 1.0 1.0 2 P31689 1 +Hindbrain development 0.2984867703390398 0.0776746006839809 0.938086898766906 1.0 1.0 40 O95456,Q7Z4L5,O94788,O43251,O14949,O15020,Q5T9L3 7 +Regulation of short term neuronal synaptic plasticity 0.4933412252145682 0.0773794546197106 0.9383216846095284 1.0 1.0 2 Q15042 1 +Isotype switching to iga isotypes 0.3809946714032002 0.0760728615140371 0.9393611309348042 1.0 1.0 3 P43246,O96028 2 +Cranial nerve development 0.3366893692626538 0.0755595281149119 0.939769536259295 1.0 1.0 4 P35222,Q9H061,P83731 3 +External encapsulating structure organization 0.2874721208632226 0.0754463888837227 0.9398595513646144 1.0 1.0 28 Q9BPX3,Q92791,Q96AY3,O75718,P07942 5 +Positive regulation of morphogenesis of an epithelium 0.4900858242083535 0.0746253219427641 0.940512826297836 1.0 1.0 2 P35222 1 +Positive regulation of oligodendrocyte differentiation 0.3207938388625568 0.0739474262599778 0.9410522184230984 1.0 1.0 5 Q15382,P42345,Q92769,O14744 4 +Regulation of myotube differentiation 0.3207938388625456 0.073947426259958 0.941052218423114 1.0 1.0 5 Q9BYT8,Q96TA1,P42345,Q16539 4 +Negative regulation of cellular amide metabolic process 0.2449647127243572 0.0734801763821058 0.9414240183806116 1.0 1.0 94 Q92945,Q5PRF9,Q9NQC3,O95197,Q9H074,P31483,Q969T7,P51116,Q10713,Q9NZN8,Q06787,P10909,Q9UKZ1,Q7Z739,Q04637,P67809,Q9Y6M1,Q96PZ0,Q00577,P12270,Q14011,O60506,P00374,Q9H2U1,Q13868,O75116,Q9BPZ3,O75298,Q9UIV1 29 +Odontogenesis 0.2952900002284461 0.0730812818385028 0.9417414367523342 1.0 1.0 13 P07942,Q6P4Q7,P35613 3 +Rna surveillance 0.3001364628115249 0.0729499886415718 0.9418459146947687 1.0 1.0 11 Q13868 1 +Grooming behavior 0.3346165235415911 0.0726562767219885 0.9420796426646688 1.0 1.0 4 P50897,P00492,Q15334 3 +Rab protein signal transduction 0.3079981730243142 0.0723019737295717 0.9423615940005328 1.0 1.0 6 Q5VZ89 1 +Mitochondrial dna repair 0.3328397986378353 0.0702194585267028 0.9440189868880398 1.0 1.0 4 Q9BQP7,P09874,P04637 3 +Proteasome mediated ubiquitin dependent protein catabolic process 0.2710312773988733 0.069232437284226 0.9448046038237808 1.0 1.0 138 O95155,Q9Y4X5,P46379,Q96A33,Q9H1I8,Q9Y5A7,Q9UBV2,Q9Y297,Q9BW61,Q13200,Q96KB5,P10909,P31749,P25787,Q13438,P33908,O15294,Q8N163,Q92990,Q04323,P49841,P51665,P17980,Q9UMX0,O15372,Q96HY6,Q8IUR7,Q9UBS8,Q8IXJ6,P49427,P49069,Q15058,Q9UJX4 33 +Response to radiation 0.24143424740496 0.0687396814834901 0.945196831633104 1.0 1.0 89 P12956,O95155,P22830,P31751,Q9BV73,Q9H1E3,Q96RU2,P29692,P50570,Q96KB5,Q70UQ0,P31749,Q8N163,Q14011,Q9H2U1,P62993,Q15555,O75844,Q9BXW9,Q9BRK5,Q96K76 21 +Positive regulation of establishment of protein localization to telomere 0.3027699988817039 0.0687108395925006 0.9452197898508736 1.0 1.0 10 P49368 1 +Establishment of protein localization to telomere 0.3027699988817039 0.0687108395925006 0.9452197898508736 1.0 1.0 10 P49368 1 +Regulation of establishment of protein localization to chromosome 0.3027699988817039 0.0687108395925006 0.9452197898508736 1.0 1.0 10 P49368 1 +Carbohydrate derivative biosynthetic process 0.2874982215808211 0.0684549586301685 0.9454234737306588 1.0 1.0 168 O95563,Q9Y287,Q99805,O60502,Q06203,Q16739,Q9UKU0,P00846,O75964,O60476,Q9HC07,Q08379,Q9H4A6,P06576,P33908,Q86YN1,Q8NBZ7,P00813,O15294,Q8TB61,Q8NCH0,Q13126,Q2TAA5,P00403,Q9Y2G5,Q8WVQ1,P31350,Q10472,Q9H9S5,Q7LGA3,Q13232 31 +Protein transport within lipid bilayer 0.4815034033737871 0.0678505442576864 0.9459046079354878 1.0 1.0 2 P05026 1 +Positive regulation of myotube differentiation 0.4803196211897091 0.0669700078848004 0.9466055798203004 1.0 1.0 2 P42345 1 +Positive regulation of cyclase activity 0.4803196211897091 0.0669700078848004 0.9466055798203004 1.0 1.0 2 P27361 1 +Immune response regulating signaling pathway 0.2927706480016402 0.0660055142443641 0.9473734352986956 1.0 1.0 61 Q96RT1,Q9NPR9,Q9Y4E8,P49770,P46379,O43657,Q9NQC3,Q9NUD5,Q07666,P15311,P09429,Q9UMX0,P00813 13 +Cellular response to inorganic substance 0.2983823951648942 0.0658290283115095 0.9475139451040576 1.0 1.0 45 P55011,P20248,P50570,Q14103,Q06787,P31749,P30536,Q9UNS1,Q9NXV6,O15111,P27361,Q99707,P09601,P05198,P16220,O95831,P35611,Q9NQ88,Q14168 19 +Telomerase holoenzyme complex assembly 0.3697454114860899 0.0651196916257913 0.9480787020579318 1.0 1.0 3 P07900,P08238 2 +Multivesicular body organization 0.2891490374693933 0.0643181350343761 0.9487169136824802 1.0 1.0 16 O43633,Q8WUX9,O14964,Q9BRG1 4 +Protection from non homologous end joining at telomere 0.3688573120189478 0.0643167632943226 0.9487180059112224 1.0 1.0 3 Q9UBB9,P18887 2 +Fibroblast proliferation 0.2826477885310656 0.0641222524681548 0.9488728833979588 1.0 1.0 18 O75844,P50402,Q71SY5 3 +Positive regulation of myelination 0.4761763835454356 0.0639881132008024 0.9489796917025906 1.0 1.0 2 O75746 1 +Positive regulation of toll like receptor 3 signaling pathway 0.4732169280852386 0.0619516919824568 0.9506013022710876 1.0 1.0 2 P41440 1 +Regulation of synaptic transmission dopaminergic 0.4732169280852386 0.0619516919824568 0.9506013022710876 1.0 1.0 2 P41440 1 +Positive regulation of heterotypic cell cell adhesion 0.4732169280852386 0.0619516919824568 0.9506013022710876 1.0 1.0 2 P41440 1 +Nucleotide excision repair dna incision 0.3256510642834704 0.0608418466380517 0.9514851632351708 1.0 1.0 4 P18074,P78549 2 +Presynaptic modulation of chemical synaptic transmission 0.4708493637170832 0.0603774612453393 0.9518550092225104 1.0 1.0 2 Q00535 1 +Regulation of synapse structural plasticity 0.4705534181710647 0.0601840690954926 0.9520090337335632 1.0 1.0 2 Q14012 1 +Apoptotic cell clearance 0.3021387444418543 0.0592652299056432 0.9527408549312192 1.0 1.0 9 Q8WTV0 1 +Phosphatidylserine metabolic process 0.3119075829383768 0.0590060468107926 0.9529472918472952 1.0 1.0 5 Q8N2K0,P48651,Q8NCC3,Q9BVG9 4 +Histone h3 k4 demethylation 0.3116113744075747 0.0585319516466629 0.9533249123801804 1.0 1.0 5 P29375,Q9H6W3,Q8NB78,O60341 4 +Nuclear envelope organization 0.2919023740431065 0.0576807851047996 0.9540028994746412 1.0 1.0 35 O43633,Q86XL3,Q14203,O94901,Q9H6H4,Q8IXJ6,P02545,Q8WUX9,O75844,Q9UH99,P50402,Q8N1F7 12 +Regulation of t cell proliferation 0.2734617342695981 0.057134924798115 0.9544377158857272 1.0 1.0 21 Q92990,P30825,Q9HCL2 3 +Regulation of vasoconstriction 0.3592415447899161 0.0561801359387881 0.9551983053913846 1.0 1.0 3 P42892 1 +Aspartate family amino acid biosynthetic process 0.2949848979014647 0.0558499594349572 0.9554613351487388 1.0 1.0 11 Q13126,Q9BV57,Q99707 3 +Extrinsic apoptotic signaling pathway 0.2954556397537008 0.0551339678956349 0.9560317348226112 1.0 1.0 41 O43464,P09601,O95677,P31749,P30154,Q9NR28,P42858 7 +Positive regulation of nervous system development 0.2970370140938563 0.054766348111169 0.95632461046537 1.0 1.0 48 P55209,P07196,P30536,Q9UQB8,Q13439,Q7L576 6 +Single strand break repair 0.3573120189461259 0.0546672810064503 0.9564035363409342 1.0 1.0 3 P09874,P18887 2 +Negative regulation of wnt signaling pathway 0.2763597236374449 0.0545303661296023 0.956512615901198 1.0 1.0 23 P25054,P50402 2 +Mhc class ii biosynthetic process 0.3567199526346996 0.0542108997467988 0.956767136713634 1.0 1.0 3 Q15545,Q96EB6 2 +Positive regulation of t cell apoptotic process 0.4598993785143595 0.0537071373586005 0.9571684962214506 1.0 1.0 2 Q9Y255 1 +Positive regulation of programmed necrotic cell death 0.4598993785143589 0.0537071373586003 0.9571684962214508 1.0 1.0 2 Q9NZI8 1 +Regulation of proteolysis 0.2894437741182799 0.0530314864923368 0.9577068204098028 1.0 1.0 174 Q9Y4X5,Q9H2J4,P46379,Q9Y5A7,O14737,Q14997,Q9Y297,Q9BW61,P61289,Q96KB5,P10909,P31749,Q96A26,Q15392,P19474,Q06323,O15294,O43464,Q8N163,Q92990,Q04323,Q96KC8,P61201,Q05086,Q9NR28,Q9UL46,P16435,O75116,O60826,Q9UMX0,O15372,O95831,Q96JB5,P49755,Q96HY6,Q9UBS8,Q8IXJ6,P78318,P35579,P49069,P09429,Q15418,Q92896,Q96K76,O75150,Q9BXK5 46 +Positive regulation of leukocyte chemotaxis 0.2895242752842573 0.0528888053573871 0.9578205039440736 1.0 1.0 14 O00429,Q4KMQ2,P09429 3 +Regulation of protein depolymerization 0.2901225200126227 0.052419961748727 0.9581940688070156 1.0 1.0 34 Q13045,P35609,Q13813,Q9BPX3,P35611,P35241,P35612,P78559,P25054,Q9NYL9,P48681,Q9UEY8,O15020,Q01082 14 +Neuron cellular homeostasis 0.2999407231772402 0.0519297462173118 0.9585846721918364 1.0 1.0 7 Q14203,P20020,P78559,Q00535,Q13131,P51790 6 +Genitalia morphogenesis 0.4563480319621275 0.0517502943439412 0.9587276618074044 1.0 1.0 2 P35222 1 +Axo dendritic transport 0.2857425884784361 0.0516576285005789 0.9588014996917265 1.0 1.0 30 P07196,O60333,Q9Y2T2,O60313,P23246,Q14168 6 +Negative regulation of protein localization to cell surface 0.3059431302826547 0.0497546505437588 0.9603179055158736 1.0 1.0 5 P35609 1 +Glandular epithelial cell differentiation 0.2992940233685084 0.0493197636020073 0.9606644696058352 1.0 1.0 8 P31749,P49841 2 +Regulation of axonogenesis 0.2826793470771817 0.0486448856292149 0.9612022987252706 1.0 1.0 28 Q7L576,P07196,Q9NQC3,Q13439 4 +Regulation of protein localization to nucleolus 0.3050354657122522 0.0484009326419877 0.961396716036959 1.0 1.0 5 Q13895 1 +Enzyme linked receptor protein signaling pathway 0.2676483090125752 0.0481943523948604 0.9615613510953992 1.0 1.0 135 Q9Y4E8,P62942,P31751,Q9Y4G8,Q9H1E3,Q9NQC3,Q8TBX8,P50570,O95470,P10586,Q9Y5X3,P31749,Q6ZWJ1,Q9UNH7,Q92572,Q8N1F7,Q7L576,Q8N0X7,P43490,O15294,Q01082,P49841,Q9UQB8,P25054,P08670,O00159,Q9UIQ6,P49815,Q96RT1,P16949,Q8IXJ6,O14964,Q9BRG1,P49069,Q8N3R9,Q92896 36 +Regulation of alternative mrna splicing via spliceosome 0.2902699483908057 0.047971374363766 0.9617390562808652 1.0 1.0 35 O75525,Q9UNW9,P62995,P98175,Q07666,O43251,P31483,P38159,Q15287,P51116,Q8IY67,Q9UHX1 12 +Histone h3 k9 modification 0.2870176783845245 0.0475159731054565 0.9621020000173184 1.0 1.0 15 Q03164 1 +Negative regulation of intrinsic apoptotic signaling pathway 0.2891775440513066 0.0468839082592707 0.9626057533390028 1.0 1.0 34 O43464,P10909,P31749,P45880,O60313,Q15233,Q96K76,P14174 8 +Response to purine containing compound 0.2822424287020262 0.0464497558479822 0.9629517798499814 1.0 1.0 17 Q86X55,Q99996,Q9Y4G8 3 +Sphingolipid metabolic process 0.288097022910652 0.0462675256673994 0.9630970223414644 1.0 1.0 33 Q16739,Q06136,Q96G23 3 +Regulation by virus of viral protein levels in host cell 0.3129997038791772 0.0461686443487591 0.9631758339987202 1.0 1.0 4 O95793,P42224,Q9P035 3 +Lymphocyte anergy 0.4445102101213456 0.0459067153265821 0.9633846017653802 1.0 1.0 2 Q96J02 1 +T cell tolerance induction 0.4445102101213456 0.0459067153265821 0.9633846017653802 1.0 1.0 2 Q96J02 1 +Uv protection 0.3125737015287756 0.0457140791310997 0.9635381420176046 1.0 1.0 4 P18074,Q9BRK5 2 +Vagina development 0.4439183190293072 0.0456406946334094 0.9635966333246382 1.0 1.0 2 Q07812 1 +Female genitalia development 0.4439183190293072 0.0456406946334094 0.9635966333246382 1.0 1.0 2 Q07812 1 +Pulmonary artery morphogenesis 0.4439183190293074 0.0456406946334094 0.9635966333246382 1.0 1.0 2 O95487 1 +Folate import across plasma membrane 0.4439183190293044 0.045640694633408 0.9635966333246392 1.0 1.0 2 P41440 1 +Leukocyte differentiation 0.2851338721755156 0.0456244482803827 0.9636095825495764 1.0 1.0 66 P12956,P0CG08,Q15648,O96005,P55327,P35579,P09429,O00625,P16220,Q14739,P00813,P24390 12 +Regulation of rna binding 0.2969968133104855 0.0455265047905574 0.9636876490289104 1.0 1.0 9 Q06787,Q9H1E3,Q86X55 3 +Serine phosphorylation of stat protein 0.4433264279372682 0.0453770660597987 0.963806760786899 1.0 1.0 2 Q00535 1 +Negative chemotaxis 0.3436944937833014 0.0450685620899744 0.9640526597674322 1.0 1.0 3 Q15375,O94813 2 +Sequestering of triglyceride 0.3118152206099988 0.0449109798831079 0.9641782649953896 1.0 1.0 4 Q9BXB4,O60664,P22413 3 +Negative regulation of cell differentiation 0.2571862683050476 0.0444057755481296 0.9645809579702248 1.0 1.0 82 P67809,Q96G23,P30536,Q8IXJ6,Q9Y4G8,Q08209,O60271,Q9NQC3,Q8N4Q0,P09429,O43707,Q8N0X7 12 +V d j recombination 0.2935073739208529 0.0436208586547714 0.9652066247192416 1.0 1.0 6 P09429 1 +Developmental induction 0.4388872447469753 0.043474733764971 0.9653231050130496 1.0 1.0 2 P35222 1 +Regulation of electron transfer activity 0.3407341622261632 0.0432208249892779 0.9655255046576284 1.0 1.0 3 O00483,Q9BSH4 2 +Regulation of complement activation 0.340734162226163 0.0432208249892776 0.9655255046576288 1.0 1.0 3 Q07021,P35232 2 +Regulation of humoral immune response 0.340734162226163 0.0432208249892776 0.9655255046576288 1.0 1.0 3 Q07021,P35232 2 +Cell cell adhesion via plasma membrane adhesion molecules 0.2707347471344882 0.0432173549790718 0.965528270740622 1.0 1.0 21 Q9BY67,Q9H3S7,P35613,O00192,O15031,Q9P273,P98194,P10586 8 +Positive regulation of telomere maintenance via telomere lengthening 0.2736689412834749 0.0421165518815701 0.9664057853846386 1.0 1.0 19 P22626,P49368,P78371,Q9H2U1 4 +Negative regulation of nucleotide metabolic process 0.4341521160106628 0.0415866183333545 0.966828241036824 1.0 1.0 2 Q9NQ88 1 +Salivary gland development 0.3365896980461812 0.0407697090808283 0.9674794879242584 1.0 1.0 3 P00533,P60953 2 +Positive regulation of glycolytic process 0.427345368452211 0.0391139093413283 0.9687995714050686 1.0 1.0 2 P05067 1 +Lung morphogenesis 0.2941874258600223 0.0382973303110576 0.9694506193296388 1.0 1.0 9 O95487,Q13247,P35222,O60568,P28482,P27361,P60953,Q02750 8 +Cellular pigmentation 0.2941002075303841 0.03723171807158 0.9703002487736268 1.0 1.0 8 O43747,Q13561,O14617,P62820,Q15907,Q9BXS5,Q96AX1 7 +Negative regulation of histone h4 acetylation 0.303523837725783 0.0366441565066133 0.970768735354886 1.0 1.0 4 Q15545,Q9NWS0,Q96EB6 3 +Error free translesion synthesis 0.4190588931636658 0.0364614204605197 0.9709144402534228 1.0 1.0 2 Q9Y2S7 1 +Negative regulation of cardiac muscle tissue growth 0.4175791654335684 0.0360265597830985 0.9712611810524916 1.0 1.0 2 P11413 1 +Negative regulation of cell growth involved in cardiac muscle cell development 0.4175791654335684 0.0360265597830985 0.9712611810524916 1.0 1.0 2 P11413 1 +Response to l phenylalanine derivative 0.4175791654335665 0.0360265597830979 0.971261181052492 1.0 1.0 2 Q96SB3 1 +Positive regulation of mirna mediated gene silencing by inhibition of translation 0.4160994377034716 0.0356029406074183 0.9715989635442368 1.0 1.0 2 Q04637 1 +Regulation of intrinsic apoptotic signaling pathway by p53 class mediator 0.2913988599032697 0.0353820887942329 0.9717750668406068 1.0 1.0 10 P61978 1 +Mitotic dna replication checkpoint signaling 0.3011548711874391 0.0344509775795556 0.9725175333440854 1.0 1.0 4 Q13564,Q9Y619,Q92547 3 +Vesicle uncoating 0.300858750370146 0.034181990049472 0.9727320280068354 1.0 1.0 4 Q9UN37,O14976,P11142 3 +Negative regulation of interferon beta production 0.4098845812370616 0.0339419772509609 0.9729234194525228 1.0 1.0 2 Q04864 1 +Ceramide transport 0.2945292484350478 0.0337560096260949 0.973071715169428 1.0 1.0 5 P07602,Q9NZJ7 2 +Inner cell mass cell differentiation 0.4063332346848273 0.0330746447176767 0.9736150622685664 1.0 1.0 2 Q6PD62 1 +Negative regulation of bone mineralization 0.4042616158626878 0.0325947900475714 0.9739977245643134 1.0 1.0 2 P22413 1 +Odontoblast differentiation 0.403373779224632 0.0323948543248918 0.9741571659899276 1.0 1.0 2 P07437 1 +Negative regulation of erad pathway 0.3188273115119222 0.0319314681332118 0.974526703487682 1.0 1.0 3 Q04323 1 +Regulation of hematopoietic stem cell proliferation 0.401006214856473 0.0318780605424361 0.9745692948970734 1.0 1.0 2 O95251 1 +Protein insertion into mitochondrial membrane involved in apoptotic signaling pathway 0.4007102693104553 0.0318151083059843 0.9746194980499993 1.0 1.0 2 Q07812 1 +Nonribosomal peptide biosynthetic process 0.2981212341403375 0.0317489865242379 0.9746722289603438 1.0 1.0 4 Q8WUX2 1 +Regulation of innate immune response 0.2936485431536068 0.0316048176858337 0.974787201352932 1.0 1.0 49 P12956,Q9BY67,Q9Y4E8,Q9BUI4,Q9Y3Z3,Q14166,Q9NZ08,Q9NUD5,P26583,Q7Z739,Q8WXF1,P23246,P09429,P19474,Q16543,Q15233,Q9UIV1,Q15648 18 +Response to hydrogen peroxide 0.2765926100218907 0.0311783705690606 0.97512728931273 1.0 1.0 26 Q05086,Q99720,P09601 3 +Protein targeting to vacuole 0.2781715416276624 0.029209435954474 0.9766975556424848 1.0 1.0 17 Q9Y2T2 1 +Regulation of retrograde transport endosome to golgi 0.3767386800828718 0.0277883305505473 0.9778309732415968 1.0 1.0 2 Q93009 1 +5 phosphoribose 1 diphosphate metabolic process 0.3072824156305479 0.0274847064441085 0.9780731377299694 1.0 1.0 3 Q14558,P06737 2 +Positive regulation of cell projection organization 0.262047563029217 0.0268027381459958 0.9786170692791456 1.0 1.0 79 P07196,Q9NZQ3,Q9Y4G8,Q9UQB8,Q66GS9,O15031,P25054,Q32P28,Q9P2S5,Q13439,O14641,Q96C92,P42858,Q7L576,Q9H6U6 15 +Regulation of protein binding 0.2916356678031732 0.0267942394768 0.9786238478016188 1.0 1.0 55 O75381,P62942,P35611,Q9Y4G8,P31749,Q08379,P30533,P48681,P16615,P35269,P10586 11 +Glomerular visceral epithelial cell migration 0.366676531518208 0.0266279463009436 0.9787564832340788 1.0 1.0 2 Q13464 1 +Copii coated vesicle budding 0.2673519228196263 0.0264290781801656 0.9789151012125512 1.0 1.0 21 Q9NR31,Q15363,O15027,Q15437,P49755 5 +Positive regulation of g protein coupled receptor signaling pathway 0.3643089671500521 0.0263919118360855 0.9789447453242744 1.0 1.0 2 O14744 1 +Meiosis ii cell cycle process 0.3637170760580127 0.0263349395124012 0.978990186867362 1.0 1.0 2 P30153 1 +Meiotic sister chromatid cohesion centromeric 0.3637170760580127 0.0263349395124012 0.978990186867362 1.0 1.0 2 P30153 1 +Regulation of dna helicase activity 0.3037300177619825 0.0262983404530579 0.9790193785814124 1.0 1.0 3 P33993,P49736 2 +Regulation of actin filament based movement 0.2893427070315669 0.0262939688852298 0.9790228653821405 1.0 1.0 9 P16615 1 +Positive regulation of intrinsic apoptotic signaling pathway in response to dna damage 0.3583900562296611 0.0258570345560697 0.9793713700348528 1.0 1.0 2 P23396 1 +Negative regulation of mhc class ii biosynthetic process 0.3566143829535441 0.0257110191278228 0.9794878347703392 1.0 1.0 2 Q15545 1 +Platelet derived growth factor receptor beta signaling pathway 0.3447765611127639 0.0248880090016526 0.980144291703564 1.0 1.0 2 P18031 1 +Modulation of age related behavioral decline 0.3444806155667433 0.0248704879344409 0.9801582671666664 1.0 1.0 2 P05067 1 +Regulation of vascular associated smooth muscle contraction 0.3435927789286858 0.0248187410141993 0.9801995424947272 1.0 1.0 2 P20020 1 +Cellular component maintenance 0.2811701857269328 0.0246063835225786 0.9803689275278172 1.0 1.0 12 Q8IUD2,Q9BRK5,Q96QK1 3 +Er nucleus signaling pathway 0.2793985004946193 0.0244069760451357 0.9805279839051132 1.0 1.0 16 P49841,Q96A33,P16615,P05198,Q15363 5 +Mhc class i biosynthetic process 0.3264279372595522 0.0240299982112701 0.980828680499251 1.0 1.0 2 Q15545 1 +Cellular response to cocaine 0.3252441550754741 0.0239884643810106 0.9808618101511064 1.0 1.0 2 P20248 1 +Dendrite morphogenesis 0.2841423040254927 0.0238310399067669 0.9809873808104564 1.0 1.0 33 Q08209,Q9UQB8,Q9Y4G8,Q05086,O60678 5 +Positive regulation of vacuole organization 0.2817777777777808 0.0235066704009336 0.981246117745753 1.0 1.0 6 Q6UWE0,Q9H2M9,Q8TBX8,Q9Y371,Q15042 5 +Maintenance of synapse structure 0.2857903153813285 0.0234637149365453 0.9812803817970428 1.0 1.0 7 Q8IUD2,Q9BRK5 2 +Dendrite self avoidance 0.2900266350991506 0.0232518753933268 0.981449359195439 1.0 1.0 2 P35613 1 +Regulation of transmission of nerve impulse 0.2820361053566234 0.0231757653313419 0.9815100698786692 1.0 1.0 2 Q06787 1 +Regulation of neuronal action potential 0.2820361053566234 0.0231757653313419 0.9815100698786692 1.0 1.0 2 Q06787 1 +Intestinal epithelial cell development 0.2817401598106036 0.0231733554658623 0.98151199215687 1.0 1.0 2 Q9NQ88 1 +Intestinal epithelial cell differentiation 0.2817401598106036 0.0231733554658623 0.98151199215687 1.0 1.0 2 Q9NQ88 1 +Positive regulation of receptor internalization 0.2907045589105911 0.0225996848977832 0.9819695951795736 1.0 1.0 3 Q06787,Q8NBU5 2 +Potassium ion import across plasma membrane 0.2844282098673628 0.0209520686837162 0.983283890921171 1.0 1.0 7 P55011,P05023,P05026 3 +Folic acid containing compound biosynthetic process 0.2800000000000032 0.0206967054294763 0.9834875971446622 1.0 1.0 6 Q6UB35,P49914,P00374,P11586,P22102 5 +Regulation of protein lipidation 0.2821195973949058 0.0206608878042921 0.9835161693652256 1.0 1.0 3 Q9H2M9,Q15042 2 +Regulation of lipoprotein metabolic process 0.2821195973949058 0.0206608878042921 0.9835161693652256 1.0 1.0 3 Q9H2M9,Q15042 2 +Motor behavior 0.2821195973949019 0.0206608878042912 0.983516169365226 1.0 1.0 3 Q13131,Q14203 2 +Sensory system development 0.2893381950986888 0.0204888032563088 0.9836534439101464 1.0 1.0 40 Q15555,O94788,P08670,P48681,Q15293,Q9H0W8 6 +Positive regulation of immune response 0.2633571772208651 0.0195978759149565 0.9843641582831856 1.0 1.0 78 P12956,Q9NUQ9,P10909,P49770,P46379,Q5RKV6,Q9NUD5,Q07666,P26583,Q8WXF1,P15311,P23246,P09429,Q07021,Q15233,P00813,Q15648 17 +Membrane repolarization during action potential 0.2823636952033677 0.0195475265251462 0.9844043235897436 1.0 1.0 4 P05023 1 +Membrane repolarization during cardiac muscle cell action potential 0.2823636952033677 0.0195475265251462 0.9844043235897436 1.0 1.0 4 P05023 1 +Spermatid differentiation 0.2674053703261359 0.0179026427601803 0.985716520735002 1.0 1.0 22 Q9H6S0,A0AVF1,P26583,Q08J23,Q96PU8,Q8N2A8,Q14997,Q07812 8 +Positive regulation of map kinase activity 0.2799246689092924 0.0177314509613868 0.9858530903494902 1.0 1.0 14 O14641,Q9H2K8 2 +Regulation of endoplasmic reticulum tubular network organization 0.2793042646086973 0.0175155321040719 0.986025341920128 1.0 1.0 4 Q9H2M9,Q15042 2 +Negative regulation of endoplasmic reticulum calcium ion concentration 0.2792419307077217 0.0174752112037176 0.986057508420729 1.0 1.0 4 P51572,Q6YHU6,Q07812 3 +Vasoconstriction 0.2793246445497603 0.0157920743006262 0.9874002714415552 1.0 1.0 5 P61586,P42892,O00443,P20020 4 +Regulation of hormone secretion 0.2803178682945066 0.015231576881296 0.9878474298728196 1.0 1.0 31 Q16836,O95563,Q08209,Q6ZWJ1,O43768,Q9UNH7,P16220 7 +Regulation of actin cytoskeleton reorganization 0.281294181278259 0.0140581206849483 0.9887836120033352 1.0 1.0 11 Q9UQB8 1 +Regulation of potassium ion transmembrane transporter activity 0.2786385862179442 0.0132568076568517 0.989422907654206 1.0 1.0 14 P35609,P50570,Q99996,P05026 4 +Negative regulation of peptidase activity 0.2886856319516023 0.013112303913643 0.9895381949390156 1.0 1.0 41 P31749,P61201,P78318,Q15392,P16435,Q15418,Q96K76 7 +Protein containing complex disassembly 0.2432855645674809 0.0130667772541078 0.9895745168460008 1.0 1.0 99 O43633,O75381,P35609,Q13813,P35611,P16949,P33176,O95721,P25054,P48681,P16615,Q8WUX9,O75844,Q01105,P13798,O15020,Q9UMX0,Q01082 18 +Response to heat 0.2859422538665654 0.0129232148901598 0.9896890533683138 1.0 1.0 37 O43464,O60884,P09601,P49841,P31749,P12270,P49770,Q9H2U1,Q99543 9 +Regulation of cellular response to heat 0.2783046828690003 0.0101513116256207 0.9919005642888884 1.0 1.0 7 Q9UHD1,P49841,Q99615,P42345,Q99543,Q96EB6 6 +Protein kinase a signaling 0.278228496799855 0.0100219628403967 0.9920037644375672 1.0 1.0 7 P14174,O00170 2 +Sphingomyelin biosynthetic process 0.2635475273911681 0.0086159314067496 0.993125566406821 1.0 1.0 4 O15270,P22059,O15269 3 +Regulation of striated muscle cell differentiation 0.2792663377344626 0.0083288588987783 0.9933546089073236 1.0 1.0 11 P67809 1 +Pteridine containing compound biosynthetic process 0.280166024310702 0.0079057827008682 0.9936921637500828 1.0 1.0 8 Q6UB35,P49914,P35270,P00374,P11586,P22102,P61457 7 +Neuron development 0.3018782287612435 0.0076081925987949 0.9939295991536454 1.0 1.0 206 Q9NZQ3,Q9UNW9,Q9Y4G8,Q08209,Q9Y4W6,Q9NQC3,Q13439,Q8WWV3,O14949,Q9H2K8,P07942,Q16739,P10586,P30536,O75312,P31749,Q9NR77,P33176,Q9Y6M7,Q32P28,O15031,O60271,Q13277,Q86X55,O00264,Q7L576,Q8N0X7,O43464,Q99707,Q96G23,Q9UQB8,Q13555,P08670,Q05086,P00374,O43251,P16220,P07196,P16949,Q15555,O43815,O60678,O14641,P09429,Q8N3R9 45 +Spindle organization 0.2365464842755459 0.0073842655636022 0.9941082620574856 1.0 1.0 89 O43633,O94927,Q9UQE7,Q9BSJ2,Q13561,Q08379,Q96DB5,Q8WXW3,P15311,Q15005,Q9H6D7,Q14203,P12270,Q9P2S5,P16949,Q15555,Q8WUX9,P35579,Q9BV86 19 +Positive regulation of neuron death 0.2633099031120993 0.0070783158707558 0.9943523682104084 1.0 1.0 21 Q07820,P10909,P49841,O95831,P49427,Q07812 6 +Negative regulation of rna splicing 0.265772042875017 0.0061987736090868 0.99505412591545 1.0 1.0 19 P22626,Q9UKA9,P98175,P38159,P61978,Q15287,Q07021 7 +Positive regulation of cellular response to insulin stimulus 0.2790105841915228 0.0056764780384969 0.9954708501367084 1.0 1.0 8 Q9Y5X3,Q9H1E3 2 +Negative regulation of supramolecular fiber organization 0.2895962437142196 0.0044851896897946 0.9964213483928231 1.0 1.0 50 Q13045,Q9BPX3,Q13813,Q9UHV9,Q9NUQ9,P35611,P10909,P16949,P35612,P25054,Q9NYL9,Q9UEY8,Q02790,O15020,Q01082,O15212 16 +Attachment of gpi anchor to protein 0.2540716612377814 0.0044082915755512 0.9964827036043112 1.0 1.0 4 Q92643,Q96S52,O43292 3 +Regulation of protein containing complex assembly 0.2522986774419212 0.0036202465742794 0.9971114674616914 1.0 1.0 115 Q13813,Q969V3,P50542,Q9NUQ9,Q9NR31,P10909,Q9NYL9,Q16625,Q04637,O95429,P23396,P11142,Q7L576,Q01082,Q14203,P49841,Q9UQB8,P35612,Q99996,P62993,Q71SY5,P45880,Q13045,Q9BPX3,P35611,P16949,Q8IXJ6,Q9UEY8,Q02790,P09429,O15020,Q15058,Q9Y6B6,Q96QK1,O15144 35 +Regulation of leukocyte chemotaxis 0.2649530689763408 0.0026330915478804 0.9978990993344166 1.0 1.0 19 O00429,Q4KMQ2,P09429,Q00013,P14174 5 +Snrna transport 0.2479779451535865 0.002103656736406 0.9983215260067712 1.0 1.0 4 Q9H814 1 +Glycerophospholipid biosynthetic process 0.2867536085974724 0.0015469363179053 0.998765723887671 1.0 1.0 41 Q9NPH0,Q9HCL2,Q9NX62,Q8TBX8,Q9UG56,Q9HBU6,P35790 7 +Kinetochore organization 0.2442996742670952 0.0008521724536903 0.9993200648383536 1.0 1.0 4 O95347,Q9BZD4,Q9NTJ3 3 +Positive regulation of mrna processing 0.2618273783175223 0.0001781743231357 0.9998578374591908 1.0 1.0 21 P62995,Q14011,P98179,Q9H2U1,P38159 5 diff --git a/msigdb_gobp/selections.json b/msigdb_gobp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..6739469cae5d76a06a17697432c5abb3599c8f8e --- /dev/null +++ b/msigdb_gobp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["10 formyltetrahydrofolate metabolic process", "2 oxoglutarate metabolic process", "2fe 2s cluster assembly", "3 phosphoadenosine 5 phosphosulfate biosynthetic process", "3 phosphoadenosine 5 phosphosulfate metabolic process", "3 utr mediated mrna destabilization", "3 utr mediated mrna stabilization", "5 phosphoribose 1 diphosphate metabolic process", "5s class rrna transcription by rna polymerase iii", "Abscission", "Acetyl coa biosynthetic process", "Acetyl coa biosynthetic process from pyruvate", "Acetyl coa metabolic process", "Acid secretion", "Acidic amino acid transport", "Acrosome assembly", "Actin crosslink formation", "Actin cytoskeleton reorganization", "Actin filament based movement", "Actin filament based process", "Actin filament based transport", "Actin filament bundle organization", "Actin filament depolymerization", "Actin filament network formation", "Actin filament organization", "Actin filament polymerization", "Actin filament reorganization", "Actin filament severing", "Actin mediated cell contraction", "Actin modification", "Actin myosin filament sliding", "Actin nucleation", "Actin polymerization dependent cell motility", "Actin polymerization or depolymerization", "Action potential", "Activated t cell proliferation", "Activation induced cell death of t cells", "Activation of adenylate cyclase activity", "Activation of cysteine type endopeptidase activity", "Activation of cysteine type endopeptidase activity involved in apoptotic process", "Activation of cysteine type endopeptidase activity involved in apoptotic process by cytochrome c", "Activation of gtpase activity", "Activation of immune response", "Activation of innate immune response", "Activation of janus kinase activity", "Activation of nf kappab inducing kinase activity", "Activation of phospholipase c activity", "Activation of phospholipase d activity", "Activation of protein kinase activity", "Activation of protein kinase b activity", "Activation of protein kinase c activity", "Activin receptor signaling pathway", "Actomyosin contractile ring organization", "Actomyosin structure organization", "Acute inflammatory response", "Acute inflammatory response to antigenic stimulus", "Acute phase response", "Acyl carnitine transmembrane transport", "Acylglycerol homeostasis", "Adaptation of signaling pathway", "Adaptive immune response", "Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains", "Adaptive thermogenesis", "Adenosine metabolic process", "Adenosine to inosine editing", "Adenylate cyclase activating adrenergic receptor signaling pathway", "Adenylate cyclase activating adrenergic receptor signaling pathway involved in heart process", "Adenylate cyclase activating g protein coupled receptor signaling pathway", "Adenylate cyclase inhibiting dopamine receptor signaling pathway", "Adenylate cyclase inhibiting g protein coupled receptor signaling pathway", "Adenylate cyclase modulating g protein coupled receptor signaling pathway", "Adherens junction assembly", "Adherens junction maintenance", "Adherens junction organization", "Adhesion of symbiont to host", "Adhesion of symbiont to host cell", "Adiponectin activated signaling pathway", "Adipose tissue development", "Adp biosynthetic process", "Adp metabolic process", "Adp transport", "Adrenal gland development", "Adrenergic receptor signaling pathway", "Adult behavior", "Adult locomotory behavior", "Aerobic respiration", "Aggrephagy", "Aggresome assembly", "Aging", "Alanine transport", "Alcohol biosynthetic process", "Alcohol catabolic process", "Alcohol metabolic process", "Aldehyde biosynthetic process", "Aldehyde catabolic process", "Alditol biosynthetic process", "Alditol catabolic process", "Alditol metabolic process", "Alditol phosphate metabolic process", "Alkanesulfonate metabolic process", "Allantoin metabolic process", "Alpha amino acid catabolic process", "Alpha amino acid metabolic process", "Alpha beta t cell activation", "Alpha beta t cell differentiation", "Alpha beta t cell proliferation", "Alpha ketoglutarate transport", "Alpha linolenic acid metabolic process", "Alternative mrna splicing via spliceosome", "Ameboidal type cell migration", "Amelogenesis", "Amide biosynthetic process", "Amide transport", "Amine biosynthetic process", "Amine catabolic process", "Amine metabolic process", "Amine transport", "Amino acid activation", "Amino acid betaine biosynthetic process", "Amino acid betaine metabolic process", "Amino acid betaine transport", "Amino acid homeostasis", "Amino acid import", "Amino acid import across plasma membrane", "Amino acid neurotransmitter reuptake", "Amino acid salvage", "Amino acid transmembrane transport", "Amino acid transport", "Amino sugar biosynthetic process", "Amino sugar catabolic process", "Amino sugar metabolic process", "Aminoacyl trna metabolism involved in translational fidelity", "Aminoglycan biosynthetic process", "Aminoglycan catabolic process", "Aminoglycan metabolic process", "Aminoglycoside antibiotic metabolic process", "Aminophospholipid translocation", "Aminophospholipid transport", "Ammonium ion metabolic process", "Ammonium transmembrane transport", "Amp biosynthetic process", "Amp catabolic process", "Amp metabolic process", "Amp salvage", "Ampa glutamate receptor clustering", "Amygdala development", "Amyloid beta clearance", "Amyloid beta clearance by cellular catabolic process", "Amyloid beta clearance by transcytosis", "Amyloid beta formation", "Amyloid beta metabolic process", "Amyloid fibril formation", "Amyloid precursor protein biosynthetic process", "Amyloid precursor protein catabolic process", "Amyloid precursor protein metabolic process", "Anagen", "Anaphase promoting complex dependent catabolic process", "Anatomical structure arrangement", "Anatomical structure formation involved in morphogenesis", "Anatomical structure homeostasis", "Anatomical structure maturation", "Androgen biosynthetic process", "Androgen catabolic process", "Androgen metabolic process", "Androgen receptor signaling pathway", "Angiogenesis involved in coronary vascular morphogenesis", "Angiogenesis involved in wound healing", "Angiotensin activated signaling pathway", "Animal organ formation", "Animal organ maturation", "Animal organ morphogenesis", "Animal organ regeneration", "Anion homeostasis", "Anion transmembrane transport", "Anion transport", "Anoikis", "Anterior head development", "Anterior posterior axis specification", "Anterior posterior pattern specification", "Anterograde axonal transport", "Anterograde axonal transport of mitochondrion", "Anterograde dendritic transport", "Anterograde dendritic transport of neurotransmitter receptor complex", "Anterograde neuronal dense core vesicle transport", "Antibacterial humoral response", "Antifungal innate immune response", "Antigen processing and presentation", "Antigen processing and presentation of endogenous antigen", "Antigen processing and presentation of endogenous peptide antigen", "Antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway", "Antigen processing and presentation of exogenous antigen", "Antigen processing and presentation of exogenous peptide antigen", "Antigen processing and presentation of exogenous peptide antigen via mhc class i", "Antigen processing and presentation of exogenous peptide antigen via mhc class ii", "Antigen processing and presentation of lipid antigen via mhc class ib", "Antigen processing and presentation of peptide antigen", "Antigen processing and presentation of peptide antigen via mhc class i", "Antigen processing and presentation of peptide antigen via mhc class ib", "Antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii", "Antigen processing and presentation via mhc class ib", "Antigen receptor mediated signaling pathway", "Antimicrobial humoral immune response mediated by antimicrobial peptide", "Antimicrobial humoral response", "Antiviral innate immune response", "Aorta development", "Aorta morphogenesis", "Aortic valve morphogenesis", "Apical junction assembly", "Apical protein localization", "Apolipoprotein a i mediated signaling pathway", "Apoptotic cell clearance", "Apoptotic chromosome condensation", "Apoptotic dna fragmentation", "Apoptotic mitochondrial changes", "Apoptotic process involved in blood vessel morphogenesis", "Apoptotic process involved in development", "Apoptotic process involved in heart morphogenesis", "Apoptotic process involved in morphogenesis", "Apoptotic signaling pathway", "Appendage development", "Appendage morphogenesis", "Arachidonic acid metabolic process", "Arachidonic acid secretion", "Arf protein signal transduction", "Arginine catabolic process", "Arginine metabolic process", "Aromatic amino acid family catabolic process", "Aromatic amino acid family metabolic process", "Aromatic amino acid transport", "Arp2 3 complex mediated actin nucleation", "Arterial endothelial cell differentiation", "Artery development", "Artery morphogenesis", "Asparagine metabolic process", "Aspartate family amino acid biosynthetic process", "Aspartate family amino acid catabolic process", "Aspartate family amino acid metabolic process", "Aspartate metabolic process", "Aspartate transmembrane transport", "Associative learning", "Astral microtubule organization", "Astrocyte activation", "Astrocyte cell migration", "Astrocyte development", "Astrocyte differentiation", "Asymmetric cell division", "Asymmetric neuroblast division", "Atf6 mediated unfolded protein response", "Atp biosynthetic process", "Atp metabolic process", "Atp synthesis coupled electron transport", "Atp synthesis coupled proton transport", "Atp transport", "Atrial cardiac muscle cell membrane repolarization", "Atrial cardiac muscle cell to av node cell signaling", "Atrial septum development", "Atrial septum morphogenesis", "Atrioventricular canal development", "Atrioventricular valve development", "Attachment of gpi anchor to protein", "Attachment of mitotic spindle microtubules to kinetochore", "Attachment of spindle microtubules to kinetochore", "Auditory receptor cell development", "Auditory receptor cell morphogenesis", "Autonomic nervous system development", "Autophagic cell death", "Autophagosome lysosome fusion", "Autophagosome maturation", "Autophagosome membrane docking", "Autophagosome organization", "Autophagy of mitochondrion", "Autophagy of nucleus", "Autophagy of peroxisome", "Axial mesoderm development", "Axis elongation", "Axis specification", "Axo dendritic protein transport", "Axo dendritic transport", "Axon choice point recognition", "Axon development", "Axon ensheathment in central nervous system", "Axon extension", "Axon midline choice point recognition", "Axonal fasciculation", "Axonal transport", "Axonal transport of mitochondrion", "Axonemal dynein complex assembly", "Axoneme assembly", "Axonogenesis involved in innervation", "Azole transmembrane transport", "B cell activation", "B cell activation involved in immune response", "B cell apoptotic process", "B cell differentiation", "B cell homeostasis", "B cell lineage commitment", "B cell mediated immunity", "B cell proliferation", "B cell receptor signaling pathway", "Barbed end actin filament capping", "Base conversion or substitution editing", "Base excision repair", "Base excision repair ap site formation", "Base excision repair gap filling", "Basement membrane assembly", "Basement membrane organization", "Basic amino acid transport", "Behavior", "Behavioral response to cocaine", "Behavioral response to ethanol", "Behavioral response to pain", "Benzene containing compound metabolic process", "Bergmann glial cell differentiation", "Bicarbonate transport", "Bile acid and bile salt transport", "Bile acid biosynthetic process", "Bile acid metabolic process", "Bile acid secretion", "Bile acid signaling pathway", "Binding of sperm to zona pellucida", "Biological adhesion", "Biological phase", "Biological process involved in interaction with host", "Biological process involved in interaction with symbiont", "Biological process involved in interspecies interaction between organisms", "Biological process involved in intraspecies interaction between organisms", "Biological process involved in symbiotic interaction", "Biomineralization", "Blastocyst development", "Blastocyst formation", "Blastocyst growth", "Blastoderm segmentation", "Bleb assembly", "Blood vessel endothelial cell differentiation", "Blood vessel endothelial cell migration", "Blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Blood vessel maturation", "Blood vessel morphogenesis", "Blood vessel remodeling", "Body fluid secretion", "Body morphogenesis", "Bone cell development", "Bone development", "Bone growth", "Bone marrow development", "Bone maturation", "Bone mineralization", "Bone morphogenesis", "Bone remodeling", "Bone resorption", "Box c d snornp assembly", "Bradykinin catabolic process", "Brain derived neurotrophic factor receptor signaling pathway", "Brain morphogenesis", "Brainstem development", "Branch elongation of an epithelium", "Branched chain amino acid biosynthetic process", "Branched chain amino acid catabolic process", "Branched chain amino acid metabolic process", "Branched chain amino acid transport", "Branching involved in blood vessel morphogenesis", "Branching involved in labyrinthine layer morphogenesis", "Branching involved in mammary gland duct morphogenesis", "Branching involved in prostate gland morphogenesis", "Branching involved in salivary gland morphogenesis", "Branching morphogenesis of a nerve", "Branching morphogenesis of an epithelial tube", "Branchiomotor neuron axon guidance", "Brown fat cell differentiation", "Bundle of his cell to purkinje myocyte communication", "C 5 methylation of cytosine", "C terminal protein amino acid modification", "C21 steroid hormone biosynthetic process", "C21 steroid hormone metabolic process", "C4 dicarboxylate transport", "Calcineurin mediated signaling", "Calcium activated phospholipid scrambling", "Calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules", "Calcium import into the mitochondrion", "Calcium ion export", "Calcium ion export across plasma membrane", "Calcium ion import", "Calcium ion import into sarcoplasmic reticulum", "Calcium ion regulated exocytosis", "Calcium ion regulated exocytosis of neurotransmitter", "Calcium ion transmembrane transport", "Calcium ion transmembrane transport via high voltage gated calcium channel", "Calcium ion transport", "Calcium ion transport into cytosol", "Calcium mediated signaling", "Calcium mediated signaling using intracellular calcium source", "Calmodulin dependent kinase signaling pathway", "Camera type eye development", "Camera type eye morphogenesis", "Camera type eye photoreceptor cell differentiation", "Camp mediated signaling", "Cannabinoid signaling pathway", "Canonical wnt signaling pathway", "Canonical wnt signaling pathway involved in cardiac muscle cell fate commitment", "Canonical wnt signaling pathway involved in heart development", "Canonical wnt signaling pathway involved in osteoblast differentiation", "Canonical wnt signaling pathway involved in regulation of cell proliferation", "Cap dependent translational initiation", "Carbohydrate biosynthetic process", "Carbohydrate catabolic process", "Carbohydrate derivative biosynthetic process", "Carbohydrate derivative catabolic process", "Carbohydrate derivative metabolic process", "Carbohydrate derivative transport", "Carbohydrate homeostasis", "Carbohydrate mediated signaling", "Carbohydrate metabolic process", "Carbohydrate phosphorylation", "Carbohydrate transmembrane transport", "Carbohydrate transport", "Carboxylic acid transport", "Cardiac atrium development", "Cardiac atrium morphogenesis", "Cardiac cell development", "Cardiac cell fate commitment", "Cardiac chamber development", "Cardiac chamber morphogenesis", "Cardiac conduction", "Cardiac conduction system development", "Cardiac epithelial to mesenchymal transition", "Cardiac left ventricle morphogenesis", "Cardiac muscle cell action potential", "Cardiac muscle cell action potential involved in contraction", "Cardiac muscle cell cardiac muscle cell adhesion", "Cardiac muscle cell contraction", "Cardiac muscle cell differentiation", "Cardiac muscle cell fate commitment", "Cardiac muscle cell membrane repolarization", "Cardiac muscle cell myoblast differentiation", "Cardiac muscle cell proliferation", "Cardiac muscle contraction", "Cardiac muscle tissue development", "Cardiac muscle tissue morphogenesis", "Cardiac neural crest cell development involved in outflow tract morphogenesis", "Cardiac neural crest cell differentiation involved in heart development", "Cardiac neural crest cell migration involved in outflow tract morphogenesis", "Cardiac septum development", "Cardiac septum morphogenesis", "Cardiac ventricle development", "Cardiac ventricle morphogenesis", "Cardioblast differentiation", "Cardioblast proliferation", "Cardiocyte differentiation", "Cardiolipin acyl chain remodeling", "Cardiolipin biosynthetic process", "Cardiolipin metabolic process", "Carnitine metabolic process", "Carnitine transport", "Cartilage development", "Cartilage development involved in endochondral bone morphogenesis", "Catechol containing compound biosynthetic process", "Catechol containing compound catabolic process", "Catechol containing compound metabolic process", "Catecholamine secretion", "Catecholamine uptake", "Catecholamine uptake involved in synaptic transmission", "Cation transmembrane transport", "Cation transport", "Caveola assembly", "Caveolin mediated endocytosis", "Cd4 positive alpha beta t cell activation", "Cd4 positive alpha beta t cell differentiation", "Cd4 positive alpha beta t cell proliferation", "Cd4 positive or cd8 positive alpha beta t cell lineage commitment", "Cd40 signaling pathway", "Cd8 positive alpha beta t cell activation", "Cd8 positive alpha beta t cell proliferation", "Cdc42 protein signal transduction", "Cdp choline pathway", "Cdp diacylglycerol metabolic process", "Cell activation", "Cell activation involved in immune response", "Cell adhesion mediated by integrin", "Cell adhesion molecule production", "Cell aggregation", "Cell aging", "Cell cell adhesion", "Cell cell adhesion involved in gastrulation", "Cell cell adhesion mediated by cadherin", "Cell cell adhesion mediated by integrin", "Cell cell adhesion via plasma membrane adhesion molecules", "Cell cell junction assembly", "Cell cell junction maintenance", "Cell cell junction organization", "Cell cell recognition", "Cell cell signaling", "Cell cell signaling by wnt", "Cell cell signaling involved in cardiac conduction", "Cell chemotaxis", "Cell communication by electrical coupling", "Cell communication by electrical coupling involved in cardiac conduction", "Cell communication involved in cardiac conduction", "Cell cycle", "Cell cycle checkpoint signaling", "Cell cycle dna replication", "Cell cycle dna replication initiation", "Cell cycle g1 s phase transition", "Cell cycle g2 m phase transition", "Cell cycle phase transition", "Cell cycle process", "Cell death in response to hydrogen peroxide", "Cell death in response to oxidative stress", "Cell differentiation in hindbrain", "Cell differentiation in spinal cord", "Cell differentiation involved in embryonic placenta development", "Cell differentiation involved in kidney development", "Cell differentiation involved in metanephros development", "Cell differentiation involved in phenotypic switching", "Cell division", "Cell fate commitment", "Cell fate commitment involved in formation of primary germ layer", "Cell fate determination", "Cell fate specification", "Cell growth", "Cell junction assembly", "Cell junction disassembly", "Cell junction maintenance", "Cell junction organization", "Cell killing", "Cell matrix adhesion", "Cell maturation", "Cell migration", "Cell migration in hindbrain", "Cell migration involved in gastrulation", "Cell migration involved in heart development", "Cell migration involved in sprouting angiogenesis", "Cell morphogenesis", "Cell morphogenesis involved in differentiation", "Cell morphogenesis involved in neuron differentiation", "Cell motility involved in cerebral cortex radial glia guided migration", "Cell part morphogenesis", "Cell projection assembly", "Cell projection organization", "Cell proliferation in forebrain", "Cell proliferation in hindbrain", "Cell proliferation involved in heart morphogenesis", "Cell proliferation involved in kidney development", "Cell proliferation involved in metanephros development", "Cell recognition", "Cell redox homeostasis", "Cell substrate adhesion", "Cell substrate junction organization", "Cell surface receptor signaling pathway involved in cell cell signaling", "Cell surface receptor signaling pathway involved in heart development", "Cell volume homeostasis", "Cellular aldehyde metabolic process", "Cellular amide metabolic process", "Cellular amino acid biosynthetic process", "Cellular amino acid catabolic process", "Cellular amino acid metabolic process", "Cellular anion homeostasis", "Cellular carbohydrate biosynthetic process", "Cellular carbohydrate catabolic process", "Cellular carbohydrate metabolic process", "Cellular component assembly involved in morphogenesis", "Cellular component disassembly", "Cellular component disassembly involved in execution phase of apoptosis", "Cellular component maintenance", "Cellular component morphogenesis", "Cellular copper ion homeostasis", "Cellular defense response", "Cellular detoxification of aldehyde", "Cellular extravasation", "Cellular glucan metabolic process", "Cellular glucose homeostasis", "Cellular homeostasis", "Cellular hormone metabolic process", "Cellular hyperosmotic response", "Cellular hyperosmotic salinity response", "Cellular hypotonic response", "Cellular ion homeostasis", "Cellular iron ion homeostasis", "Cellular ketone metabolic process", "Cellular lipid catabolic process", "Cellular lipid metabolic process", "Cellular macromolecule biosynthetic process", "Cellular macromolecule localization", "Cellular metabolic compound salvage", "Cellular modified amino acid biosynthetic process", "Cellular modified amino acid catabolic process", "Cellular modified amino acid metabolic process", "Cellular monovalent inorganic anion homeostasis", "Cellular monovalent inorganic cation homeostasis", "Cellular nitrogen compound catabolic process", "Cellular oxidant detoxification", "Cellular pigmentation", "Cellular polysaccharide catabolic process", "Cellular potassium ion homeostasis", "Cellular process involved in reproduction in multicellular organism", "Cellular protein catabolic process", "Cellular respiration", "Cellular response to abiotic stimulus", "Cellular response to acid chemical", "Cellular response to acidic ph", "Cellular response to alcohol", "Cellular response to aldehyde", "Cellular response to alkaloid", "Cellular response to amyloid beta", "Cellular response to antibiotic", "Cellular response to arsenic containing substance", "Cellular response to atp", "Cellular response to biotic stimulus", "Cellular response to brain derived neurotrophic factor stimulus", "Cellular response to cadmium ion", "Cellular response to caffeine", "Cellular response to calcium ion", "Cellular response to camp", "Cellular response to carbohydrate stimulus", "Cellular response to chemical stress", "Cellular response to cocaine", "Cellular response to cold", "Cellular response to copper ion", "Cellular response to corticosteroid stimulus", "Cellular response to dexamethasone stimulus", "Cellular response to dna damage stimulus", "Cellular response to dsrna", "Cellular response to electrical stimulus", "Cellular response to endogenous stimulus", "Cellular response to epinephrine stimulus", "Cellular response to estradiol stimulus", "Cellular response to estrogen stimulus", "Cellular response to ethanol", "Cellular response to ether", "Cellular response to exogenous dsrna", "Cellular response to external stimulus", "Cellular response to extracellular stimulus", "Cellular response to fatty acid", "Cellular response to fluid shear stress", "Cellular response to follicle stimulating hormone stimulus", "Cellular response to gamma radiation", "Cellular response to glucose starvation", "Cellular response to gonadotropin stimulus", "Cellular response to growth hormone stimulus", "Cellular response to heat", "Cellular response to heparin", "Cellular response to histamine", "Cellular response to hormone stimulus", "Cellular response to hydrogen peroxide", "Cellular response to hydroperoxide", "Cellular response to hyperoxia", "Cellular response to increased oxygen levels", "Cellular response to indole 3 methanol", "Cellular response to inorganic substance", "Cellular response to insulin like growth factor stimulus", "Cellular response to insulin stimulus", "Cellular response to interferon alpha", "Cellular response to interferon beta", "Cellular response to interferon gamma", "Cellular response to interleukin 1", "Cellular response to ionizing radiation", "Cellular response to iron ion", "Cellular response to ketone", "Cellular response to leptin stimulus", "Cellular response to leucine", "Cellular response to leucine starvation", "Cellular response to light intensity", "Cellular response to light stimulus", "Cellular response to lipid", "Cellular response to lipoprotein particle stimulus", "Cellular response to lithium ion", "Cellular response to low density lipoprotein particle stimulus", "Cellular response to magnesium ion", "Cellular response to manganese ion", "Cellular response to mechanical stimulus", "Cellular response to mineralocorticoid stimulus", "Cellular response to molecule of bacterial origin", "Cellular response to muramyl dipeptide", "Cellular response to nitrogen compound", "Cellular response to nitrogen starvation", "Cellular response to nitrosative stress", "Cellular response to nutrient", "Cellular response to organic cyclic compound", "Cellular response to osmotic stress", "Cellular response to oxidised low density lipoprotein particle stimulus", "Cellular response to oxygen containing compound", "Cellular response to oxygen glucose deprivation", "Cellular response to oxygen levels", "Cellular response to oxygen radical", "Cellular response to parathyroid hormone stimulus", "Cellular response to peptide", "Cellular response to peptide hormone stimulus", "Cellular response to peptidoglycan", "Cellular response to ph", "Cellular response to potassium ion", "Cellular response to prostaglandin e stimulus", "Cellular response to prostaglandin stimulus", "Cellular response to purine containing compound", "Cellular response to radiation", "Cellular response to reactive nitrogen species", "Cellular response to reactive oxygen species", "Cellular response to retinoic acid", "Cellular response to salt", "Cellular response to salt stress", "Cellular response to sodium arsenite", "Cellular response to starvation", "Cellular response to steroid hormone stimulus", "Cellular response to sterol depletion", "Cellular response to stress", "Cellular response to testosterone stimulus", "Cellular response to thyroid hormone stimulus", "Cellular response to topologically incorrect protein", "Cellular response to toxic substance", "Cellular response to unfolded protein", "Cellular response to uv", "Cellular response to uv a", "Cellular response to uv c", "Cellular response to vascular endothelial growth factor stimulus", "Cellular response to virus", "Cellular response to vitamin", "Cellular response to vitamin d", "Cellular response to water stimulus", "Cellular response to x ray", "Cellular response to xenobiotic stimulus", "Cellular response to zinc ion", "Cellular senescence", "Cellular sodium ion homeostasis", "Cellular sphingolipid homeostasis", "Cellular transition metal ion homeostasis", "Cellular triglyceride homeostasis", "Cellular trivalent inorganic anion homeostasis", "Cenp a containing chromatin organization", "Central nervous system development", "Central nervous system maturation", "Central nervous system myelin formation", "Central nervous system myelin maintenance", "Central nervous system neuron axonogenesis", "Central nervous system neuron development", "Central nervous system neuron differentiation", "Central nervous system projection neuron axonogenesis", "Centriole assembly", "Centriole centriole cohesion", "Centriole elongation", "Centromere complex assembly", "Centromeric sister chromatid cohesion", "Centrosome duplication", "Centrosome separation", "Ceramide biosynthetic process", "Ceramide catabolic process", "Ceramide metabolic process", "Ceramide transport", "Cerebellar cortex development", "Cerebellar cortex formation", "Cerebellar cortex morphogenesis", "Cerebellar granular layer development", "Cerebellar granular layer morphogenesis", "Cerebellar purkinje cell layer development", "Cerebellar purkinje cell layer formation", "Cerebellar purkinje cell layer morphogenesis", "Cerebral cortex cell migration", "Cerebral cortex development", "Cerebral cortex neuron differentiation", "Cerebral cortex radially oriented cell migration", "Cerebral cortex regionalization", "Cerebral cortex tangential migration", "Cgmp mediated signaling", "Changes to dna methylation involved in embryo development", "Chaperone cofactor dependent protein refolding", "Chaperone mediated autophagy", "Chaperone mediated protein complex assembly", "Chaperone mediated protein folding", "Chemical homeostasis", "Chemical homeostasis within a tissue", "Chemical synaptic transmission postsynaptic", "Chemokine c c motif ligand 5 production", "Chemokine c x c motif ligand 12 signaling pathway", "Chemokine c x c motif ligand 2 production", "Chemokine production", "Chemosensory behavior", "Chloride transmembrane transport", "Chloride transport", "Cholesterol catabolic process", "Cholesterol efflux", "Cholesterol storage", "Choline metabolic process", "Chondroblast differentiation", "Chondrocyte development", "Chondrocyte development involved in endochondral bone morphogenesis", "Chondrocyte differentiation", "Chondrocyte differentiation involved in endochondral bone morphogenesis", "Chondrocyte proliferation", "Chondroitin sulfate biosynthetic process", "Chondroitin sulfate proteoglycan biosynthetic process", "Chondroitin sulfate proteoglycan metabolic process", "Chorio allantoic fusion", "Chorion development", "Chromatin assembly or disassembly", "Chromatin disassembly", "Chromatin organization", "Chromatin remodeling", "Chromatin remodeling at centromere", "Chromosome attachment to the nuclear envelope", "Chromosome condensation", "Chromosome localization", "Chromosome localization to nuclear envelope involved in homologous chromosome segregation", "Chromosome movement towards spindle pole", "Chromosome organization", "Chromosome organization involved in meiotic cell cycle", "Chromosome segregation", "Chromosome separation", "Cilium movement", "Cilium or flagellum dependent cell motility", "Cilium organization", "Circadian regulation of gene expression", "Circadian rhythm", "Circulatory system development", "Circulatory system process", "Citrate metabolic process", "Citrulline biosynthetic process", "Citrulline metabolic process", "Clathrin coat assembly", "Clathrin dependent endocytosis", "Cleavage furrow formation", "Cleavage involved in rrna processing", "Cobalamin metabolic process", "Cobalamin transport", "Cochlea development", "Cochlea morphogenesis", "Coenzyme a biosynthetic process", "Coenzyme a metabolic process", "Cognition", "Cohesin loading", "Collagen biosynthetic process", "Collagen catabolic process", "Collagen fibril organization", "Collagen metabolic process", "Collateral sprouting", "Collateral sprouting in absence of injury", "Collecting duct development", "Columnar cuboidal epithelial cell development", "Columnar cuboidal epithelial cell differentiation", "Columnar cuboidal epithelial cell maturation", "Commissural neuron axon guidance", "Common partner smad protein phosphorylation", "Complement activation", "Complement dependent cytotoxicity", "Connective tissue development", "Connective tissue replacement", "Constitutive heterochromatin assembly", "Constitutive secretory pathway", "Convergent extension", "Convergent extension involved in axis elongation", "Convergent extension involved in gastrulation", "Convergent extension involved in organogenesis", "Cop9 signalosome assembly", "Copi coated vesicle budding", "Copii coated vesicle budding", "Copii coated vesicle cargo loading", "Copper ion homeostasis", "Copper ion transport", "Copulation", "Coronary artery morphogenesis", "Coronary vasculature development", "Coronary vasculature morphogenesis", "Corpus callosum development", "Corpus callosum morphogenesis", "Cortical actin cytoskeleton organization", "Cortical cytoskeleton organization", "Corticospinal tract morphogenesis", "Corticosteroid hormone secretion", "Corticosteroid receptor signaling pathway", "Corticotropin secretion", "Cortisol secretion", "Cotranslational protein targeting to membrane", "Cranial ganglion development", "Cranial nerve development", "Cranial nerve morphogenesis", "Cranial nerve structural organization", "Cranial skeletal system development", "Craniofacial suture morphogenesis", "Crd mediated mrna stabilization", "Cristae formation", "Cyclic gmp amp transmembrane import across plasma membrane", "Cyclic nucleotide biosynthetic process", "Cyclic nucleotide catabolic process", "Cyclic nucleotide mediated signaling", "Cyclic nucleotide metabolic process", "Cyclooxygenase pathway", "Cysteine metabolic process", "Cytidine metabolic process", "Cytidine to uridine editing", "Cytochrome complex assembly", "Cytokine mediated signaling pathway", "Cytokine production", "Cytokine production involved in immune response", "Cytokine production involved in inflammatory response", "Cytokinesis", "Cytokinetic process", "Cytoplasm organization", "Cytoplasmic microtubule organization", "Cytoplasmic pattern recognition receptor signaling pathway", "Cytoplasmic pattern recognition receptor signaling pathway in response to virus", "Cytoplasmic sequestering of nf kappab", "Cytoplasmic sequestering of protein", "Cytoplasmic sequestering of transcription factor", "Cytoplasmic translation", "Cytoplasmic translational elongation", "Cytoplasmic translational initiation", "Cytoskeleton dependent cytokinesis", "Cytoskeleton dependent intracellular transport", "Cytoskeleton organization", "Cytosolic calcium ion transport", "Cytosolic transport", "D amino acid transport", "Damp metabolic process", "De novo amp biosynthetic process", "De novo protein folding", "De novo pyrimidine nucleobase biosynthetic process", "Deadenylation dependent decapping of nuclear transcribed mrna", "Decidualization", "Dedifferentiation", "Defense response", "Defense response to bacterium", "Defense response to fungus", "Defense response to gram negative bacterium", "Defense response to gram positive bacterium", "Defense response to other organism", "Defense response to symbiont", "Defense response to tumor cell", "Definitive erythrocyte differentiation", "Definitive hemopoiesis", "Delamination", "Demethylation", "Dendrite arborization", "Dendrite development", "Dendrite extension", "Dendrite morphogenesis", "Dendrite self avoidance", "Dendritic cell apoptotic process", "Dendritic cell chemotaxis", "Dendritic cell cytokine production", "Dendritic cell differentiation", "Dendritic cell migration", "Dendritic spine development", "Dendritic spine maintenance", "Dendritic spine morphogenesis", "Dendritic transport", "Dense core granule transport", "Dentate gyrus development", "Deoxyribonucleoside catabolic process", "Deoxyribonucleoside diphosphate metabolic process", "Deoxyribonucleoside metabolic process", "Deoxyribonucleoside monophosphate biosynthetic process", "Deoxyribonucleoside monophosphate catabolic process", "Deoxyribonucleoside monophosphate metabolic process", "Deoxyribonucleoside triphosphate biosynthetic process", "Deoxyribonucleoside triphosphate catabolic process", "Deoxyribonucleoside triphosphate metabolic process", "Deoxyribonucleotide biosynthetic process", "Deoxyribose phosphate catabolic process", "Deoxyribose phosphate metabolic process", "Dephosphorylation", "Dephosphorylation of rna polymerase ii c terminal domain", "Depyrimidination", "Dermatan sulfate biosynthetic process", "Dermatan sulfate metabolic process", "Dermatan sulfate proteoglycan metabolic process", "Desmosome organization", "Detection of abiotic stimulus", "Detection of biotic stimulus", "Detection of calcium ion", "Detection of cell density", "Detection of external biotic stimulus", "Detection of light stimulus", "Detection of light stimulus involved in sensory perception", "Detection of mechanical stimulus", "Detection of molecule of bacterial origin", "Detection of muscle stretch", "Detection of other organism", "Detection of stimulus", "Detection of stimulus involved in sensory perception", "Detection of virus", "Detection of visible light", "Determination of adult lifespan", "Determination of dorsal ventral asymmetry", "Detoxification", "Detoxification of copper ion", "Detoxification of nitrogen compound", "Development of primary female sexual characteristics", "Development of primary sexual characteristics", "Development of secondary female sexual characteristics", "Development of secondary sexual characteristics", "Developmental cell growth", "Developmental growth", "Developmental growth involved in morphogenesis", "Developmental induction", "Developmental maturation", "Developmental pigmentation", "Developmental process involved in reproduction", "Diacylglycerol biosynthetic process", "Diacylglycerol metabolic process", "Diadenosine polyphosphate metabolic process", "Diapedesis", "Diaphragm development", "Dicarboxylic acid biosynthetic process", "Dicarboxylic acid catabolic process", "Dicarboxylic acid metabolic process", "Dicarboxylic acid transport", "Dichotomous subdivision of an epithelial terminal unit", "Dichotomous subdivision of terminal units involved in salivary gland branching", "Diencephalon development", "Diet induced thermogenesis", "Digestion", "Digestive system development", "Digestive system process", "Digestive tract morphogenesis", "Diol biosynthetic process", "Diol metabolic process", "Disaccharide metabolic process", "Diterpenoid biosynthetic process", "Divalent inorganic cation homeostasis", "Dna biosynthetic process", "Dna catabolic process", "Dna catabolic process endonucleolytic", "Dna catabolic process exonucleolytic", "Dna conformation change", "Dna cytosine deamination", "Dna damage induced protein phosphorylation", "Dna damage response signal transduction by p53 class mediator", "Dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest", "Dna damage response signal transduction resulting in transcription", "Dna dealkylation", "Dna dealkylation involved in dna repair", "Dna deamination", "Dna dependent dna replication", "Dna dependent dna replication maintenance of fidelity", "Dna double strand break processing", "Dna endoreduplication", "Dna geometric change", "Dna integration", "Dna integrity checkpoint signaling", "Dna ligation", "Dna ligation involved in dna repair", "Dna metabolic process", "Dna methylation", "Dna methylation dependent heterochromatin assembly", "Dna methylation involved in gamete generation", "Dna methylation on cytosine", "Dna methylation or demethylation", "Dna modification", "Dna packaging", "Dna protection", "Dna recombination", "Dna repair", "Dna replication", "Dna replication checkpoint signaling", "Dna replication dependent chromatin organization", "Dna replication independent chromatin organization", "Dna replication initiation", "Dna replication synthesis of rna primer", "Dna strand elongation", "Dna strand elongation involved in dna replication", "Dna synthesis involved in dna repair", "Dna templated transcription elongation", "Dna templated transcription initiation", "Dna templated transcription termination", "Dna topological change", "Dna unwinding involved in dna replication", "Dolichol metabolic process", "Dolichyl diphosphate biosynthetic process", "Dopamine biosynthetic process", "Dopamine metabolic process", "Dopamine receptor signaling pathway", "Dopamine secretion", "Dopamine transport", "Dopaminergic neuron differentiation", "Dorsal aorta development", "Dorsal aorta morphogenesis", "Dorsal root ganglion development", "Dorsal ventral axis specification", "Dorsal ventral neural tube patterning", "Dorsal ventral pattern formation", "Dosage compensation", "Double strand break repair", "Double strand break repair involved in meiotic recombination", "Double strand break repair via break induced replication", "Double strand break repair via classical nonhomologous end joining", "Double strand break repair via nonhomologous end joining", "Double strand break repair via synthesis dependent strand annealing", "Dsrna processing", "Dtmp metabolic process", "Dttp metabolic process", "Dump metabolic process", "Ear development", "Ear morphogenesis", "Early endosome to golgi transport", "Eating behavior", "Ectoderm development", "Ectodermal cell differentiation", "Ectodermal placode development", "Ectopic germ cell programmed cell death", "Egg activation", "Electron transport chain", "Embryo development", "Embryo development ending in birth or egg hatching", "Embryo implantation", "Embryonic appendage morphogenesis", "Embryonic axis specification", "Embryonic body morphogenesis", "Embryonic brain development", "Embryonic camera type eye development", "Embryonic cleavage", "Embryonic cranial skeleton morphogenesis", "Embryonic digestive tract development", "Embryonic digestive tract morphogenesis", "Embryonic digit morphogenesis", "Embryonic forelimb morphogenesis", "Embryonic heart tube development", "Embryonic heart tube morphogenesis", "Embryonic hemopoiesis", "Embryonic hindlimb morphogenesis", "Embryonic morphogenesis", "Embryonic neurocranium morphogenesis", "Embryonic organ development", "Embryonic organ morphogenesis", "Embryonic pattern specification", "Embryonic placenta development", "Embryonic placenta morphogenesis", "Embryonic process involved in female pregnancy", "Embryonic skeletal joint development", "Embryonic skeletal joint morphogenesis", "Embryonic skeletal system development", "Embryonic skeletal system morphogenesis", "Embryonic viscerocranium morphogenesis", "Enamel mineralization", "Endocannabinoid signaling pathway", "Endocardial cushion development", "Endocardial cushion formation", "Endocardial cushion morphogenesis", "Endocardium development", "Endocardium morphogenesis", "Endochondral bone morphogenesis", "Endocrine hormone secretion", "Endocrine pancreas development", "Endocrine process", "Endocrine system development", "Endocytic recycling", "Endocytosis", "Endocytosis involved in viral entry into host cell", "Endoderm development", "Endoderm formation", "Endodermal cell differentiation", "Endodermal cell fate commitment", "Endomembrane system organization", "Endonucleolytic cleavage in 5 ets of tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage in its1 to separate ssu rrna from 5 8s rrna and lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage involved in rrna processing", "Endoplasmic reticulum calcium ion homeostasis", "Endoplasmic reticulum localization", "Endoplasmic reticulum mannose trimming", "Endoplasmic reticulum membrane organization", "Endoplasmic reticulum organization", "Endoplasmic reticulum plasma membrane tethering", "Endoplasmic reticulum to cytosol transport", "Endoplasmic reticulum to golgi vesicle mediated transport", "Endoplasmic reticulum tubular network organization", "Endoplasmic reticulum unfolded protein response", "Endosomal lumen acidification", "Endosomal transport", "Endosomal vesicle fusion", "Endosome organization", "Endosome to lysosome transport", "Endosome to lysosome transport via multivesicular body sorting pathway", "Endosome to plasma membrane protein transport", "Endosome transport via multivesicular body sorting pathway", "Endothelial cell activation", "Endothelial cell apoptotic process", "Endothelial cell chemotaxis", "Endothelial cell development", "Endothelial cell fate commitment", "Endothelial cell matrix adhesion", "Endothelial cell migration", "Endothelial cell morphogenesis", "Endothelial cell proliferation", "Endothelin receptor signaling pathway", "Endothelium development", "Energy derivation by oxidation of organic compounds", "Energy homeostasis", "Energy reserve metabolic process", "Engulfment of apoptotic cell", "Ensheathment of neurons", "Enteroendocrine cell differentiation", "Entrainment of circadian clock", "Entry into host", "Entry of bacterium into host cell", "Enucleate erythrocyte differentiation", "Enzyme directed rrna pseudouridine synthesis", "Enzyme linked receptor protein signaling pathway", "Eosinophil activation", "Eosinophil chemotaxis", "Eosinophil mediated immunity", "Eosinophil migration", "Ephrin receptor signaling pathway", "Epiboly", "Epidermal cell differentiation", "Epidermis development", "Epidermis morphogenesis", "Epigenetic maintenance of chromatin in transcription competent conformation", "Epithelial cell apoptotic process", "Epithelial cell cell adhesion", "Epithelial cell development", "Epithelial cell differentiation", "Epithelial cell differentiation involved in kidney development", "Epithelial cell differentiation involved in prostate gland development", "Epithelial cell fate commitment", "Epithelial cell maturation", "Epithelial cell morphogenesis", "Epithelial cell proliferation", "Epithelial cell proliferation involved in lung morphogenesis", "Epithelial cell proliferation involved in prostate gland development", "Epithelial fluid transport", "Epithelial structure maintenance", "Epithelial to mesenchymal transition", "Epithelial to mesenchymal transition involved in endocardial cushion formation", "Epithelial tube branching involved in lung morphogenesis", "Epithelial tube formation", "Epithelial tube morphogenesis", "Epithelium development", "Epoxide metabolic process", "Er associated misfolded protein catabolic process", "Er nucleus signaling pathway", "Er overload response", "Erad pathway", "Erbb signaling pathway", "Erbb2 signaling pathway", "Erk1 and erk2 cascade", "Error free translesion synthesis", "Error prone translesion synthesis", "Erythrocyte development", "Erythrocyte homeostasis", "Erythrocyte maturation", "Escrt complex disassembly", "Establishment of cell polarity", "Establishment of centrosome localization", "Establishment of endothelial barrier", "Establishment of endothelial intestinal barrier", "Establishment of epithelial cell apical basal polarity", "Establishment of epithelial cell polarity", "Establishment of golgi localization", "Establishment of lymphocyte polarity", "Establishment of meiotic spindle localization", "Establishment of mitochondrion localization", "Establishment of mitotic spindle localization", "Establishment of organelle localization", "Establishment of pigment granule localization", "Establishment of planar polarity involved in neural tube closure", "Establishment of planar polarity of embryonic epithelium", "Establishment of protein localization", "Establishment of protein localization to chromatin", "Establishment of protein localization to chromosome", "Establishment of protein localization to endoplasmic reticulum", "Establishment of protein localization to membrane", "Establishment of protein localization to mitochondrial membrane", "Establishment of protein localization to organelle", "Establishment of protein localization to plasma membrane", "Establishment of protein localization to telomere", "Establishment of protein localization to vacuole", "Establishment of rna localization", "Establishment of sister chromatid cohesion", "Establishment of spindle orientation", "Establishment of tissue polarity", "Establishment or maintenance of bipolar cell polarity", "Establishment or maintenance of cell polarity", "Establishment or maintenance of cytoskeleton polarity", "Establishment or maintenance of monopolar cell polarity", "Establishment or maintenance of transmembrane electrochemical gradient", "Estrogen biosynthetic process", "Estrogen metabolic process", "Estrous cycle", "Ethanol catabolic process", "Ethanol metabolic process", "Ethanol oxidation", "Ether biosynthetic process", "Ether metabolic process", "Excitatory synapse assembly", "Excretion", "Execution phase of apoptosis", "Exit from mitosis", "Exocrine pancreas development", "Exocrine system development", "Exocyst localization", "Exocytic process", "Exocytosis", "Exonucleolytic catabolism of deadenylated mrna", "Exploration behavior", "Export across plasma membrane", "Export from cell", "External encapsulating structure organization", "Extracellular exosome assembly", "Extracellular matrix assembly", "Extracellular matrix constituent secretion", "Extracellular matrix disassembly", "Extracellular regulation of signal transduction", "Extracellular transport", "Extracellular vesicle biogenesis", "Extraembryonic membrane development", "Extrinsic apoptotic signaling pathway", "Extrinsic apoptotic signaling pathway via death domain receptors", "Eye morphogenesis", "Eye photoreceptor cell development", "Eye photoreceptor cell differentiation", "Eyelid development in camera type eye", "Face development", "Facial nerve morphogenesis", "Facial nerve structural organization", "Facultative heterochromatin assembly", "Farnesyl diphosphate metabolic process", "Fas signaling pathway", "Fat cell differentiation", "Fat cell proliferation", "Fat soluble vitamin metabolic process", "Fatty acid alpha oxidation", "Fatty acid beta oxidation", "Fatty acid beta oxidation using acyl coa dehydrogenase", "Fatty acid beta oxidation using acyl coa oxidase", "Fatty acid biosynthetic process", "Fatty acid catabolic process", "Fatty acid derivative biosynthetic process", "Fatty acid derivative catabolic process", "Fatty acid derivative metabolic process", "Fatty acid elongation", "Fatty acid homeostasis", "Fatty acid metabolic process", "Fatty acid omega oxidation", "Fatty acid transmembrane transport", "Fatty acid transport", "Fatty acyl coa biosynthetic process", "Fatty acyl coa catabolic process", "Fatty acyl coa metabolic process", "Fc epsilon receptor signaling pathway", "Fc gamma receptor signaling pathway", "Fc receptor mediated inhibitory signaling pathway", "Fc receptor mediated stimulatory signaling pathway", "Fc receptor signaling pathway", "Fear response", "Feeding behavior", "Female gamete generation", "Female genitalia development", "Female meiosis chromosome segregation", "Female meiosis i", "Female meiotic nuclear division", "Female sex differentiation", "Fermentation", "Fertilization", "Fibroblast activation", "Fibroblast apoptotic process", "Fibroblast growth factor production", "Fibroblast growth factor receptor signaling pathway", "Fibroblast migration", "Fibroblast proliferation", "Filopodium assembly", "Flavin containing compound metabolic process", "Flavonoid metabolic process", "Fluid transport", "Foam cell differentiation", "Focal adhesion assembly", "Folate import across plasma membrane", "Folate transmembrane transport", "Folic acid containing compound biosynthetic process", "Folic acid containing compound catabolic process", "Folic acid containing compound metabolic process", "Folic acid metabolic process", "Folic acid transport", "Forebrain cell migration", "Forebrain development", "Forebrain dorsal ventral pattern formation", "Forebrain generation of neurons", "Forebrain morphogenesis", "Forebrain neuron development", "Forebrain neuron differentiation", "Forebrain neuron fate commitment", "Forebrain radial glial cell differentiation", "Forebrain regionalization", "Foregut morphogenesis", "Forelimb morphogenesis", "Formate metabolic process", "Formation of extrachromosomal circular dna", "Formation of primary germ layer", "Formation of translation preinitiation complex", "Free ubiquitin chain polymerization", "Fructose 1 6 bisphosphate metabolic process", "Fructose 2 6 bisphosphate metabolic process", "Fructose 6 phosphate metabolic process", "Fructose metabolic process", "Fucose metabolic process", "Fucosylation", "Fungiform papilla development", "Fungiform papilla morphogenesis", "G protein coupled acetylcholine receptor signaling pathway", "G protein coupled glutamate receptor signaling pathway", "G protein coupled opioid receptor signaling pathway", "G protein coupled purinergic receptor signaling pathway", "G protein coupled receptor internalization", "G protein coupled receptor signaling pathway", "G protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger", "G protein coupled receptor signaling pathway involved in heart process", "G quadruplex dna unwinding", "G0 to g1 transition", "G1 to g0 transition", "G2 mi transition of meiotic cell cycle", "Galactolipid biosynthetic process", "Galactolipid metabolic process", "Galactose catabolic process", "Galactose metabolic process", "Gamete generation", "Gamma aminobutyric acid metabolic process", "Gamma aminobutyric acid secretion", "Gamma aminobutyric acid signaling pathway", "Gamma aminobutyric acid transport", "Ganglion development", "Ganglioside catabolic process", "Ganglioside metabolic process", "Gap junction assembly", "Gap junction mediated intercellular transport", "Gas homeostasis", "Gastrulation", "Gastrulation with mouth forming second", "Gdp mannose metabolic process", "Gdp metabolic process", "Gene silencing by rna", "Generation of precursor metabolites and energy", "Genitalia development", "Genitalia morphogenesis", "Genomic imprinting", "Germ cell development", "Germ cell migration", "Germ cell proliferation", "Germinal center b cell differentiation", "Germinal center formation", "Gland development", "Gland morphogenesis", "Glandular epithelial cell development", "Glandular epithelial cell differentiation", "Glial cell apoptotic process", "Glial cell development", "Glial cell differentiation", "Glial cell fate commitment", "Glial cell migration", "Glial cell proliferation", "Gliogenesis", "Glomerular basement membrane development", "Glomerular epithelial cell development", "Glomerular epithelial cell differentiation", "Glomerular epithelium development", "Glomerular visceral epithelial cell migration", "Glomerulus development", "Glucan biosynthetic process", "Glucocorticoid biosynthetic process", "Glucocorticoid metabolic process", "Glucocorticoid secretion", "Glucosamine containing compound catabolic process", "Glucosamine containing compound metabolic process", "Glucose 6 phosphate metabolic process", "Glucose catabolic process", "Glucose import", "Glucose import in response to insulin stimulus", "Glucose metabolic process", "Glucosylceramide metabolic process", "Glutamate biosynthetic process", "Glutamate catabolic process", "Glutamate homeostasis", "Glutamate metabolic process", "Glutamate receptor signaling pathway", "Glutamate reuptake", "Glutamate secretion", "Glutamate secretion neurotransmission", "Glutamine family amino acid biosynthetic process", "Glutamine family amino acid catabolic process", "Glutamine family amino acid metabolic process", "Glutamine metabolic process", "Glutamine transport", "Glutathione catabolic process", "Glutathione metabolic process", "Glycerol 3 phosphate metabolic process", "Glycerol ether metabolic process", "Glycerolipid biosynthetic process", "Glycerolipid catabolic process", "Glycerolipid metabolic process", "Glycerophospholipid biosynthetic process", "Glycerophospholipid catabolic process", "Glycerophospholipid metabolic process", "Glycine biosynthetic process", "Glycine metabolic process", "Glycolipid biosynthetic process", "Glycolipid catabolic process", "Glycolipid transport", "Glycolytic fermentation", "Glycolytic process through fructose 6 phosphate", "Glycoprotein biosynthetic process", "Glycoprotein catabolic process", "Glycoprotein metabolic process", "Glycosaminoglycan catabolic process", "Glycoside catabolic process", "Glycoside metabolic process", "Glycosphingolipid biosynthetic process", "Glycosphingolipid metabolic process", "Glycosyl compound biosynthetic process", "Glycosyl compound catabolic process", "Glycosyl compound metabolic process", "Glycosylation", "Glycosylceramide biosynthetic process", "Glycosylceramide catabolic process", "Glycosylceramide metabolic process", "Glyoxylate metabolic process", "Gmp biosynthetic process", "Gmp metabolic process", "Gmp salvage", "Golgi disassembly", "Golgi localization", "Golgi organization", "Golgi ribbon formation", "Golgi to endosome transport", "Golgi to lysosome transport", "Golgi to plasma membrane protein transport", "Golgi to plasma membrane transport", "Golgi to vacuole transport", "Golgi vesicle budding", "Golgi vesicle transport", "Gonadotropin secretion", "Gpi anchor metabolic process", "Granulocyte activation", "Granulocyte chemotaxis", "Granulocyte differentiation", "Granulocyte migration", "Granzyme mediated programmed cell death signaling pathway", "Grooming behavior", "Growth", "Growth hormone receptor signaling pathway via jak stat", "Growth hormone secretion", "Growth plate cartilage chondrocyte differentiation", "Growth plate cartilage development", "Gtp biosynthetic process", "Gtp metabolic process", "Guanine metabolic process", "Guanine nucleotide transmembrane transport", "Guanine nucleotide transport", "Hair cell differentiation", "Hair cycle phase", "Hair follicle maturation", "Hair follicle placode formation", "Hard palate development", "Head development", "Head morphogenesis", "Heart development", "Heart field specification", "Heart formation", "Heart growth", "Heart morphogenesis", "Heart process", "Heart trabecula formation", "Heart trabecula morphogenesis", "Heart valve development", "Heart valve morphogenesis", "Heat acclimation", "Heat generation", "Hematopoietic progenitor cell differentiation", "Hematopoietic stem cell differentiation", "Hematopoietic stem cell homeostasis", "Hematopoietic stem cell proliferation", "Heme transport", "Hemidesmosome assembly", "Hemoglobin biosynthetic process", "Hemoglobin metabolic process", "Hemostasis", "Heparan sulfate proteoglycan biosynthetic process", "Heparan sulfate proteoglycan biosynthetic process enzymatic modification", "Heparan sulfate proteoglycan biosynthetic process polysaccharide chain biosynthetic process", "Heparan sulfate proteoglycan metabolic process", "Heparin metabolic process", "Hepatic stellate cell activation", "Hepaticobiliary system development", "Hepatocyte apoptotic process", "Hepatocyte differentiation", "Hepatocyte growth factor receptor signaling pathway", "Hepoxilin metabolic process", "Heterochromatin organization", "Heterophilic cell cell adhesion via plasma membrane cell adhesion molecules", "Heterotypic cell cell adhesion", "High density lipoprotein particle assembly", "High density lipoprotein particle clearance", "High density lipoprotein particle remodeling", "Hindbrain development", "Hindbrain maturation", "Hindbrain morphogenesis", "Hindbrain radial glia guided cell migration", "Hindgut development", "Hindlimb morphogenesis", "Hippo signaling", "Hippocampus development", "His purkinje system development", "Histamine production involved in inflammatory response", "Histamine secretion", "Histamine transport", "Histidine metabolic process", "Histone arginine methylation", "Histone deacetylation", "Histone dephosphorylation", "Histone deubiquitination", "Histone exchange", "Histone h2a acetylation", "Histone h2a k63 linked ubiquitination", "Histone h2a monoubiquitination", "Histone h2a phosphorylation", "Histone h2a ubiquitination", "Histone h2b ubiquitination", "Histone h3 acetylation", "Histone h3 deacetylation", "Histone h3 k14 acetylation", "Histone h3 k27 demethylation", "Histone h3 k27 methylation", "Histone h3 k27 trimethylation", "Histone h3 k36 demethylation", "Histone h3 k36 methylation", "Histone h3 k36 trimethylation", "Histone h3 k4 demethylation", "Histone h3 k4 demethylation trimethyl h3 k4 specific", "Histone h3 k4 dimethylation", "Histone h3 k4 methylation", "Histone h3 k4 monomethylation", "Histone h3 k4 trimethylation", "Histone h3 k9 acetylation", "Histone h3 k9 demethylation", "Histone h3 k9 dimethylation", "Histone h3 k9 methylation", "Histone h3 k9 modification", "Histone h3 k9 trimethylation", "Histone h4 acetylation", "Histone h4 deacetylation", "Histone h4 k12 acetylation", "Histone h4 k16 acetylation", "Histone h4 k20 methylation", "Histone h4 k20 trimethylation", "Histone h4 k5 acetylation", "Histone h4 r3 methylation", "Histone lysine demethylation", "Histone methylation", "Histone modification", "Histone monoubiquitination", "Histone mrna catabolic process", "Histone mrna metabolic process", "Histone phosphorylation", "Histone serine phosphorylation", "Histone threonine phosphorylation", "Histone ubiquitination", "Homeostasis of number of cells", "Homeostasis of number of cells within a tissue", "Homeostatic process", "Homocysteine metabolic process", "Homologous chromosome pairing at meiosis", "Homologous chromosome segregation", "Homologous recombination", "Homophilic cell adhesion via plasma membrane adhesion molecules", "Homotypic cell cell adhesion", "Hormone biosynthetic process", "Hormone catabolic process", "Hormone mediated signaling pathway", "Hormone metabolic process", "Hormone transport", "Humoral immune response", "Humoral immune response mediated by circulating immunoglobulin", "Hyaluronan biosynthetic process", "Hyaluronan metabolic process", "Hydrogen peroxide biosynthetic process", "Hydrogen peroxide catabolic process", "Hydrogen peroxide metabolic process", "Hydrogen sulfide biosynthetic process", "Hydrogen sulfide metabolic process", "Hyperosmotic response", "Hyperosmotic salinity response", "Hypothalamus cell differentiation", "Hypothalamus cell migration", "Hypothalamus development", "Hypothalamus gonadotrophin releasing hormone neuron differentiation", "Hypotonic response", "Hypoxia inducible factor 1alpha signaling pathway", "I kappab kinase nf kappab signaling", "I kappab phosphorylation", "Icosanoid biosynthetic process", "Icosanoid metabolic process", "Icosanoid transport", "Immune complex clearance", "Immune effector process", "Immune response", "Immune response inhibiting cell surface receptor signaling pathway", "Immune response inhibiting signal transduction", "Immune response regulating cell surface receptor signaling pathway", "Immune response regulating signaling pathway", "Immune response to tumor cell", "Immune system development", "Immunoglobulin production", "Immunoglobulin production involved in immunoglobulin mediated immune response", "Immunoglobulin v d j recombination", "Immunological synapse formation", "Imp biosynthetic process", "Imp catabolic process", "Imp metabolic process", "Imp salvage", "Import across plasma membrane", "Import into cell", "Import into nucleus", "In utero embryonic development", "Inclusion body assembly", "Indolalkylamine metabolic process", "Indole containing compound biosynthetic process", "Indole containing compound metabolic process", "Induction of positive chemotaxis", "Inflammasome complex assembly", "Inflammatory cell apoptotic process", "Inflammatory response", "Inflammatory response to antigenic stimulus", "Inflammatory response to wounding", "Inhibitory postsynaptic potential", "Innate immune response", "Innate immune response activating signal transduction", "Innate immune response in mucosa", "Inner cell mass cell differentiation", "Inner cell mass cell proliferation", "Inner dynein arm assembly", "Inner ear auditory receptor cell differentiation", "Inner ear morphogenesis", "Inner ear receptor cell development", "Inner ear receptor cell fate commitment", "Inner ear receptor cell stereocilium organization", "Inner mitochondrial membrane organization", "Innervation", "Inorganic anion transmembrane transport", "Inorganic anion transport", "Inorganic ion import across plasma membrane", "Inorganic ion transmembrane transport", "Inosine metabolic process", "Inositol lipid mediated signaling", "Inositol metabolic process", "Inositol phosphate catabolic process", "Inositol phosphate mediated signaling", "Inositol phosphate metabolic process", "Insulin like growth factor receptor signaling pathway", "Insulin metabolic process", "Insulin processing", "Insulin receptor signaling pathway", "Insulin secretion", "Insulin secretion involved in cellular response to glucose stimulus", "Integrated stress response signaling", "Integrin activation", "Integrin mediated signaling pathway", "Intercellular transport", "Interferon alpha production", "Interferon beta production", "Interferon gamma mediated signaling pathway", "Interferon gamma production", "Interleukin 1 alpha production", "Interleukin 1 mediated signaling pathway", "Interleukin 1 production", "Interleukin 10 production", "Interleukin 12 production", "Interleukin 13 production", "Interleukin 17 production", "Interleukin 18 mediated signaling pathway", "Interleukin 18 production", "Interleukin 2 production", "Interleukin 23 production", "Interleukin 27 mediated signaling pathway", "Interleukin 6 mediated signaling pathway", "Interleukin 6 production", "Interleukin 8 production", "Intermediate filament based process", "Intermediate filament bundle assembly", "Intermediate filament organization", "Intermembrane lipid transfer", "Interstrand cross link repair", "Intestinal absorption", "Intestinal epithelial cell development", "Intestinal epithelial cell differentiation", "Intestinal hexose absorption", "Intestinal lipid absorption", "Intra golgi vesicle mediated transport", "Intracellular distribution of mitochondria", "Intracellular estrogen receptor signaling pathway", "Intracellular lipid transport", "Intracellular mrna localization", "Intracellular protein transmembrane transport", "Intracellular protein transport", "Intracellular receptor signaling pathway", "Intracellular sterol transport", "Intracellular transport", "Intracellular transport of virus", "Intraciliary retrograde transport", "Intraciliary transport", "Intraciliary transport involved in cilium assembly", "Intrinsic apoptotic signaling pathway", "Intrinsic apoptotic signaling pathway by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to dna damage", "Intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress", "Intrinsic apoptotic signaling pathway in response to hydrogen peroxide", "Intrinsic apoptotic signaling pathway in response to hypoxia", "Intrinsic apoptotic signaling pathway in response to osmotic stress", "Intrinsic apoptotic signaling pathway in response to oxidative stress", "Iodide transport", "Ion homeostasis", "Ion transmembrane transport", "Ion transport", "Ire1 mediated unfolded protein response", "Ires dependent viral translational initiation", "Iron coordination entity transport", "Iron import into cell", "Iron ion homeostasis", "Iron ion import across plasma membrane", "Iron ion transmembrane transport", "Iron ion transport", "Iron sulfur cluster assembly", "Isocitrate metabolic process", "Isoleucine metabolic process", "Isopentenyl diphosphate biosynthetic process", "Isoprenoid biosynthetic process", "Isoprenoid metabolic process", "Isotype switching to iga isotypes", "Isotype switching to igg isotypes", "Jnk cascade", "Keratan sulfate metabolic process", "Keratinization", "Keratinocyte development", "Keratinocyte differentiation", "Keratinocyte migration", "Keratinocyte proliferation", "Ketone biosynthetic process", "Ketone body biosynthetic process", "Ketone body metabolic process", "Ketone catabolic process", "Kidney epithelium development", "Kidney mesenchyme development", "Kidney morphogenesis", "Killing by host of symbiont cells", "Killing of cells of another organism", "Kinetochore assembly", "Kinetochore organization", "Kynurenine metabolic process", "L alanine transport", "L alpha amino acid transmembrane transport", "L amino acid transport", "L arginine import across plasma membrane", "L arginine transmembrane transport", "L ascorbic acid metabolic process", "L aspartate transmembrane transport", "L glutamate import across plasma membrane", "L glutamate transmembrane transport", "L histidine transmembrane transport", "L kynurenine metabolic process", "L lysine transmembrane transport", "L methionine salvage from methylthioadenosine", "L phenylalanine metabolic process", "L proline biosynthetic process", "L serine biosynthetic process", "L serine catabolic process", "L serine metabolic process", "L serine transport", "Labyrinthine layer blood vessel development", "Labyrinthine layer development", "Labyrinthine layer morphogenesis", "Lactate metabolic process", "Lactate transmembrane transport", "Lactation", "Lamellipodium assembly", "Lamellipodium morphogenesis", "Lamellipodium organization", "Late endosome to golgi transport", "Late endosome to lysosome transport", "Late endosome to vacuole transport", "Late endosome to vacuole transport via multivesicular body sorting pathway", "Late nucleophagy", "Lateral ventricle development", "Layer formation in cerebral cortex", "Learned vocalization behavior or vocal learning", "Learning", "Lens development in camera type eye", "Lens fiber cell development", "Lens fiber cell differentiation", "Lens morphogenesis in camera type eye", "Leptin mediated signaling pathway", "Leucine catabolic process", "Leucine import across plasma membrane", "Leucine metabolic process", "Leucine transport", "Leukocyte adhesion to vascular endothelial cell", "Leukocyte aggregation", "Leukocyte apoptotic process", "Leukocyte cell cell adhesion", "Leukocyte chemotaxis", "Leukocyte degranulation", "Leukocyte differentiation", "Leukocyte homeostasis", "Leukocyte mediated cytotoxicity", "Leukocyte mediated immunity", "Leukocyte migration", "Leukocyte proliferation", "Leukocyte tethering or rolling", "Leukotriene b4 metabolic process", "Leukotriene biosynthetic process", "Leukotriene metabolic process", "Leukotriene transport", "Leydig cell differentiation", "Ligand gated ion channel signaling pathway", "Limb joint morphogenesis", "Limbic system development", "Linoleic acid metabolic process", "Lipid biosynthetic process", "Lipid catabolic process", "Lipid digestion", "Lipid droplet formation", "Lipid droplet organization", "Lipid export from cell", "Lipid glycosylation", "Lipid homeostasis", "Lipid import into cell", "Lipid localization", "Lipid metabolic process", "Lipid modification", "Lipid oxidation", "Lipid phosphorylation", "Lipid storage", "Lipid translocation", "Lipid transport across blood brain barrier", "Lipophagy", "Lipopolysaccharide mediated signaling pathway", "Lipoprotein biosynthetic process", "Lipoprotein catabolic process", "Lipoprotein localization", "Lipoprotein metabolic process", "Liposaccharide metabolic process", "Lipoxin metabolic process", "Liver morphogenesis", "Liver regeneration", "Localization within membrane", "Locomotion", "Locomotion involved in locomotory behavior", "Locomotor rhythm", "Locomotory behavior", "Locomotory exploration behavior", "Long chain fatty acid biosynthetic process", "Long chain fatty acid import across plasma membrane", "Long chain fatty acid metabolic process", "Long chain fatty acid transport", "Long chain fatty acyl coa biosynthetic process", "Long chain fatty acyl coa metabolic process", "Long term memory", "Long term synaptic depression", "Long term synaptic potentiation", "Low density lipoprotein particle clearance", "Low density lipoprotein receptor particle metabolic process", "Lung alveolus development", "Lung associated mesenchyme development", "Lung cell differentiation", "Lung epithelium development", "Lung growth", "Lung lobe development", "Lung morphogenesis", "Lung saccule development", "Lung secretory cell differentiation", "Luteinization", "Luteinizing hormone secretion", "Luteolysis", "Lymphocyte activation", "Lymphocyte activation involved in immune response", "Lymphocyte aggregation", "Lymphocyte anergy", "Lymphocyte apoptotic process", "Lymphocyte chemotaxis", "Lymphocyte costimulation", "Lymphocyte homeostasis", "Lymphocyte mediated immunity", "Lymphocyte migration", "Lymphocyte migration into lymphoid organs", "Lymphoid progenitor cell differentiation", "Lysine catabolic process", "Lysine metabolic process", "Lysosomal lumen acidification", "Lysosomal membrane organization", "Lysosomal microautophagy", "Lysosomal protein catabolic process", "Lysosomal transport", "Lytic vacuole organization", "Macroautophagy", "Macromolecule catabolic process", "Macromolecule deacylation", "Macromolecule depalmitoylation", "Macrophage activation", "Macrophage apoptotic process", "Macrophage chemotaxis", "Macrophage cytokine production", "Macrophage differentiation", "Macrophage fusion", "Macrophage inflammatory protein 1 alpha production", "Macrophage migration", "Macrophage proliferation", "Macropinocytosis", "Magnesium ion homeostasis", "Magnesium ion transport", "Maintenance of animal organ identity", "Maintenance of apical basal cell polarity", "Maintenance of blood brain barrier", "Maintenance of cell number", "Maintenance of cell polarity", "Maintenance of centrosome location", "Maintenance of dna methylation", "Maintenance of dna repeat elements", "Maintenance of gastrointestinal epithelium", "Maintenance of lens transparency", "Maintenance of location", "Maintenance of location in cell", "Maintenance of organelle location", "Maintenance of postsynaptic specialization structure", "Maintenance of presynaptic active zone structure", "Maintenance of protein localization in endoplasmic reticulum", "Maintenance of protein localization in organelle", "Maintenance of protein location", "Maintenance of protein location in cell", "Maintenance of protein location in mitochondrion", "Maintenance of protein location in nucleus", "Maintenance of sister chromatid cohesion", "Maintenance of synapse structure", "Malate metabolic process", "Male gamete generation", "Male genitalia development", "Male mating behavior", "Male meiosis i", "Male meiotic nuclear division", "Male sex determination", "Male sex differentiation", "Malonyl coa metabolic process", "Mammalian oogenesis stage", "Mammary gland alveolus development", "Mammary gland branching involved in pregnancy", "Mammary gland development", "Mammary gland duct morphogenesis", "Mammary gland epithelial cell differentiation", "Mammary gland epithelial cell proliferation", "Mammary gland epithelium development", "Mammary gland involution", "Mammary gland morphogenesis", "Manganese ion transmembrane transport", "Manganese ion transport", "Mannose metabolic process", "Mannosylation", "Mapk cascade", "Mast cell activation", "Mast cell activation involved in immune response", "Mast cell cytokine production", "Mast cell proliferation", "Maternal placenta development", "Maternal process involved in female pregnancy", "Mating", "Mating behavior", "Maturation of 5 8s rrna", "Maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of lsu rrna", "Maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of ssu rrna", "Maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Mature b cell differentiation", "Mature ribosome assembly", "Mda 5 signaling pathway", "Mechanoreceptor differentiation", "Mechanosensory behavior", "Medium chain fatty acid biosynthetic process", "Medium chain fatty acid catabolic process", "Medium chain fatty acid metabolic process", "Medium chain fatty acyl coa metabolic process", "Megakaryocyte development", "Megakaryocyte differentiation", "Meiosis i cell cycle process", "Meiosis ii cell cycle process", "Meiotic cell cycle", "Meiotic cell cycle checkpoint signaling", "Meiotic cell cycle phase transition", "Meiotic cell cycle process", "Meiotic chromosome condensation", "Meiotic chromosome segregation", "Meiotic chromosome separation", "Meiotic cytokinesis", "Meiotic dna double strand break formation", "Meiotic sister chromatid cohesion centromeric", "Meiotic spindle assembly", "Meiotic spindle organization", "Melanocyte differentiation", "Membrane biogenesis", "Membrane depolarization", "Membrane depolarization during action potential", "Membrane depolarization during cardiac muscle cell action potential", "Membrane disassembly", "Membrane docking", "Membrane fission", "Membrane fusion", "Membrane fusion involved in viral entry into host cell", "Membrane hyperpolarization", "Membrane invagination", "Membrane lipid biosynthetic process", "Membrane lipid catabolic process", "Membrane lipid metabolic process", "Membrane organization", "Membrane protein ectodomain proteolysis", "Membrane protein intracellular domain proteolysis", "Membrane protein proteolysis", "Membrane raft assembly", "Membrane raft localization", "Membrane raft organization", "Membrane repolarization", "Membrane repolarization during action potential", "Membrane repolarization during atrial cardiac muscle cell action potential", "Membrane repolarization during cardiac muscle cell action potential", "Membrane to membrane docking", "Membranous septum morphogenesis", "Memory", "Mesangial cell development", "Mesangial cell differentiation", "Mesenchymal cell development", "Mesenchymal cell differentiation", "Mesenchymal cell differentiation involved in kidney development", "Mesenchymal cell proliferation", "Mesenchymal cell proliferation involved in lung development", "Mesenchymal stem cell differentiation", "Mesenchymal stem cell proliferation", "Mesenchymal to epithelial transition", "Mesenchymal to epithelial transition involved in metanephros morphogenesis", "Mesenchyme development", "Mesenchyme morphogenesis", "Mesoderm development", "Mesoderm morphogenesis", "Mesodermal cell differentiation", "Mesonephric duct development", "Mesonephric tubule formation", "Mesonephric tubule morphogenesis", "Mesonephros development", "Metal ion export", "Metal ion homeostasis", "Metal ion transport", "Metanephric collecting duct development", "Metanephric epithelium development", "Metanephric glomerulus development", "Metanephric glomerulus vasculature development", "Metanephric mesenchymal cell differentiation", "Metanephric mesenchyme development", "Metanephric nephron development", "Metanephric nephron morphogenesis", "Metanephric nephron tubule epithelial cell differentiation", "Metanephric part of ureteric bud development", "Metanephric renal vesicle morphogenesis", "Metanephric tubule development", "Metanephros development", "Metanephros morphogenesis", "Metaphase anaphase transition of cell cycle", "Metaphase plate congression", "Metencephalon development", "Methionine biosynthetic process", "Methionine metabolic process", "Methylation", "Methylglyoxal metabolic process", "Methylguanosine cap decapping", "Mhc class i biosynthetic process", "Mhc class ii biosynthetic process", "Microglia differentiation", "Microglial cell activation", "Microglial cell proliferation", "Microtubule anchoring", "Microtubule anchoring at centrosome", "Microtubule anchoring at microtubule organizing center", "Microtubule based movement", "Microtubule based process", "Microtubule based transport", "Microtubule bundle formation", "Microtubule cytoskeleton organization", "Microtubule cytoskeleton organization involved in mitosis", "Microtubule depolymerization", "Microtubule nucleation", "Microtubule organizing center localization", "Microtubule organizing center organization", "Microtubule polymerization", "Microtubule polymerization or depolymerization", "Microtubule severing", "Microvillus assembly", "Microvillus organization", "Midbody abscission", "Midbrain development", "Midbrain dopaminergic neuron differentiation", "Middle ear morphogenesis", "Midgut development", "Minus end directed organelle transport along microtubule", "Mirna catabolic process", "Mirna loading onto risc involved in gene silencing by mirna", "Mirna metabolic process", "Mismatch repair", "Mitochondrial acetyl coa biosynthetic process from pyruvate", "Mitochondrial adp transmembrane transport", "Mitochondrial atp synthesis coupled proton transport", "Mitochondrial calcium ion homeostasis", "Mitochondrial calcium ion transmembrane transport", "Mitochondrial cytochrome c oxidase assembly", "Mitochondrial depolarization", "Mitochondrial dna metabolic process", "Mitochondrial dna repair", "Mitochondrial dna replication", "Mitochondrial electron transport cytochrome c to oxygen", "Mitochondrial electron transport nadh to ubiquinone", "Mitochondrial electron transport ubiquinol to cytochrome c", "Mitochondrial fission", "Mitochondrial fragmentation involved in apoptotic process", "Mitochondrial fusion", "Mitochondrial gene expression", "Mitochondrial genome maintenance", "Mitochondrial membrane organization", "Mitochondrial outer membrane permeabilization", "Mitochondrial outer membrane permeabilization involved in programmed cell death", "Mitochondrial protein catabolic process", "Mitochondrial protein processing", "Mitochondrial proton transporting atp synthase complex assembly", "Mitochondrial respirasome assembly", "Mitochondrial respiratory chain complex assembly", "Mitochondrial ribosome assembly", "Mitochondrial rna 3 end processing", "Mitochondrial rna catabolic process", "Mitochondrial rna metabolic process", "Mitochondrial rna modification", "Mitochondrial rna processing", "Mitochondrial transcription", "Mitochondrial translation", "Mitochondrial translational elongation", "Mitochondrial transmembrane transport", "Mitochondrial transport", "Mitochondrial trna processing", "Mitochondrion distribution", "Mitochondrion endoplasmic reticulum membrane tethering", "Mitochondrion localization", "Mitochondrion morphogenesis", "Mitochondrion organization", "Mitophagy", "Mitotic cell cycle", "Mitotic cell cycle checkpoint signaling", "Mitotic cell cycle phase transition", "Mitotic cell cycle process", "Mitotic chromosome condensation", "Mitotic cytokinesis", "Mitotic cytokinetic process", "Mitotic dna integrity checkpoint signaling", "Mitotic dna replication", "Mitotic dna replication checkpoint signaling", "Mitotic g1 s transition checkpoint signaling", "Mitotic g2 dna damage checkpoint signaling", "Mitotic g2 m transition checkpoint", "Mitotic intra s dna damage checkpoint signaling", "Mitotic metaphase plate congression", "Mitotic nuclear division", "Mitotic nuclear membrane disassembly", "Mitotic nuclear membrane organization", "Mitotic recombination", "Mitotic sister chromatid cohesion", "Mitotic sister chromatid segregation", "Mitotic spindle assembly", "Mitotic spindle midzone assembly", "Mitotic spindle organization", "Modification dependent macromolecule catabolic process", "Modification of postsynaptic actin cytoskeleton", "Modification of postsynaptic structure", "Modification of synaptic structure", "Modified amino acid transport", "Modulation by host of symbiont catalytic activity", "Modulation by host of symbiont process", "Modulation by host of viral genome replication", "Modulation by host of viral process", "Modulation of age related behavioral decline", "Modulation of excitatory postsynaptic potential", "Molting cycle", "Monoacylglycerol catabolic process", "Monoacylglycerol metabolic process", "Monoamine transport", "Monocarboxylic acid biosynthetic process", "Monocarboxylic acid catabolic process", "Monocarboxylic acid metabolic process", "Monocarboxylic acid transport", "Monocyte activation", "Monocyte chemotactic protein 1 production", "Monocyte chemotaxis", "Monocyte differentiation", "Monocyte extravasation", "Mononuclear cell differentiation", "Mononuclear cell migration", "Monosaccharide biosynthetic process", "Monosaccharide catabolic process", "Monosaccharide metabolic process", "Monoubiquitinated protein deubiquitination", "Monovalent inorganic anion homeostasis", "Monovalent inorganic cation homeostasis", "Morphogenesis of a branching structure", "Morphogenesis of a polarized epithelium", "Morphogenesis of an endothelium", "Morphogenesis of an epithelial bud", "Morphogenesis of an epithelial fold", "Morphogenesis of an epithelial sheet", "Morphogenesis of an epithelium", "Morphogenesis of embryonic epithelium", "Motor behavior", "Motor learning", "Motor neuron apoptotic process", "Motor neuron axon guidance", "Motor neuron migration", "Mrna 3 end processing", "Mrna 3 end processing by stem loop binding and cleavage", "Mrna 3 splice site recognition", "Mrna 5 splice site recognition", "Mrna alternative polyadenylation", "Mrna catabolic process", "Mrna cis splicing via spliceosome", "Mrna cleavage", "Mrna cleavage involved in mrna processing", "Mrna destabilization mediated gene silencing", "Mrna export from nucleus", "Mrna metabolic process", "Mrna methylation", "Mrna modification", "Mrna processing", "Mrna pseudouridine synthesis", "Mrna splice site selection", "Mrna transcription", "Mrna transport", "Mucopolysaccharide metabolic process", "Mucosa associated lymphoid tissue development", "Mucus secretion", "Multi multicellular organism process", "Multi organism reproductive process", "Multicellular organism aging", "Multicellular organism growth", "Multicellular organism reproduction", "Multicellular organismal homeostasis", "Multicellular organismal movement", "Multicellular organismal response to stress", "Multicellular organismal signaling", "Multinuclear osteoclast differentiation", "Multivesicular body organization", "Multivesicular body sorting pathway", "Muscle adaptation", "Muscle cell apoptotic process", "Muscle cell cellular homeostasis", "Muscle cell development", "Muscle cell differentiation", "Muscle cell fate commitment", "Muscle cell migration", "Muscle cell proliferation", "Muscle contraction", "Muscle hypertrophy", "Muscle hypertrophy in response to stress", "Muscle organ development", "Muscle organ morphogenesis", "Muscle structure development", "Muscle system process", "Muscle tissue development", "Myd88 dependent toll like receptor signaling pathway", "Myd88 independent toll like receptor signaling pathway", "Myelin assembly", "Myelin maintenance", "Myeloid cell activation involved in immune response", "Myeloid cell apoptotic process", "Myeloid cell development", "Myeloid cell differentiation", "Myeloid cell homeostasis", "Myeloid dendritic cell activation", "Myeloid dendritic cell cytokine production", "Myeloid dendritic cell differentiation", "Myeloid leukocyte activation", "Myeloid leukocyte cytokine production", "Myeloid leukocyte differentiation", "Myeloid leukocyte mediated immunity", "Myeloid leukocyte migration", "Myeloid progenitor cell differentiation", "Myoblast differentiation", "Myoblast fusion", "Myoblast migration", "Myoblast proliferation", "Myofibroblast differentiation", "Myosin filament organization", "Myotube cell development", "Myotube differentiation", "N acetylglucosamine metabolic process", "N acetylneuraminate catabolic process", "N acetylneuraminate metabolic process", "N glycan processing", "N terminal peptidyl methionine acetylation", "N terminal protein amino acid acetylation", "N terminal protein amino acid modification", "N terminal protein lipidation", "Nad biosynthesis via nicotinamide riboside salvage pathway", "Nad metabolic process", "Nadh dehydrogenase complex assembly", "Nadh metabolic process", "Nadh oxidation", "Nadh regeneration", "Nadp metabolic process", "Nadph regeneration", "Natural killer cell activation", "Natural killer cell activation involved in immune response", "Natural killer cell degranulation", "Natural killer cell differentiation", "Natural killer cell mediated immune response to tumor cell", "Natural killer cell mediated immunity", "Ncrna 3 end processing", "Ncrna catabolic process", "Ncrna export from nucleus", "Ncrna metabolic process", "Ncrna processing", "Ncrna transcription", "Necroptotic signaling pathway", "Necrotic cell death", "Negative chemotaxis", "Negative regulation by host of viral genome replication", "Negative regulation by host of viral process", "Negative regulation by host of viral transcription", "Negative regulation of actin filament bundle assembly", "Negative regulation of actin filament depolymerization", "Negative regulation of actin filament polymerization", "Negative regulation of actin nucleation", "Negative regulation of activated t cell proliferation", "Negative regulation of activin receptor signaling pathway", "Negative regulation of adaptive immune response", "Negative regulation of adenylate cyclase activating adrenergic receptor signaling pathway", "Negative regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Negative regulation of adenylate cyclase activity", "Negative regulation of alcohol biosynthetic process", "Negative regulation of alpha beta t cell activation", "Negative regulation of alpha beta t cell differentiation", "Negative regulation of alpha beta t cell proliferation", "Negative regulation of amine transport", "Negative regulation of amino acid transport", "Negative regulation of amyloid beta clearance", "Negative regulation of amyloid fibril formation", "Negative regulation of amyloid precursor protein biosynthetic process", "Negative regulation of amyloid precursor protein catabolic process", "Negative regulation of androgen receptor signaling pathway", "Negative regulation of anion transmembrane transport", "Negative regulation of anion transport", "Negative regulation of anoikis", "Negative regulation of antigen receptor mediated signaling pathway", "Negative regulation of apoptotic signaling pathway", "Negative regulation of arp2 3 complex mediated actin nucleation", "Negative regulation of astrocyte activation", "Negative regulation of astrocyte differentiation", "Negative regulation of atp biosynthetic process", "Negative regulation of atp dependent activity", "Negative regulation of atp metabolic process", "Negative regulation of atpase coupled calcium transmembrane transporter activity", "Negative regulation of autophagosome assembly", "Negative regulation of autophagosome maturation", "Negative regulation of autophagy", "Negative regulation of autophagy of mitochondrion", "Negative regulation of axon extension", "Negative regulation of axon extension involved in axon guidance", "Negative regulation of axonogenesis", "Negative regulation of b cell activation", "Negative regulation of b cell apoptotic process", "Negative regulation of b cell differentiation", "Negative regulation of b cell mediated immunity", "Negative regulation of b cell proliferation", "Negative regulation of behavior", "Negative regulation of bicellular tight junction assembly", "Negative regulation of binding", "Negative regulation of biomineralization", "Negative regulation of biosynthetic process", "Negative regulation of blood circulation", "Negative regulation of blood pressure", "Negative regulation of blood vessel endothelial cell migration", "Negative regulation of bmp signaling pathway", "Negative regulation of bone mineralization", "Negative regulation of bone remodeling", "Negative regulation of calcineurin mediated signaling", "Negative regulation of calcium ion dependent exocytosis", "Negative regulation of calcium ion import", "Negative regulation of calcium ion transmembrane transport", "Negative regulation of calcium ion transport", "Negative regulation of calcium ion transport into cytosol", "Negative regulation of calcium mediated signaling", "Negative regulation of camp dependent protein kinase activity", "Negative regulation of camp mediated signaling", "Negative regulation of canonical wnt signaling pathway", "Negative regulation of carbohydrate metabolic process", "Negative regulation of cardiac muscle adaptation", "Negative regulation of cardiac muscle contraction", "Negative regulation of cardiac muscle tissue growth", "Negative regulation of cardiocyte differentiation", "Negative regulation of cartilage development", "Negative regulation of catabolic process", "Negative regulation of catalytic activity", "Negative regulation of catecholamine secretion", "Negative regulation of cation channel activity", "Negative regulation of cd4 positive alpha beta t cell activation", "Negative regulation of cd4 positive alpha beta t cell differentiation", "Negative regulation of cd4 positive alpha beta t cell proliferation", "Negative regulation of cell activation", "Negative regulation of cell adhesion", "Negative regulation of cell adhesion mediated by integrin", "Negative regulation of cell aging", "Negative regulation of cell cell adhesion", "Negative regulation of cell cell adhesion mediated by cadherin", "Negative regulation of cell cycle", "Negative regulation of cell cycle checkpoint", "Negative regulation of cell cycle g1 s phase transition", "Negative regulation of cell cycle g2 m phase transition", "Negative regulation of cell cycle phase transition", "Negative regulation of cell cycle process", "Negative regulation of cell death", "Negative regulation of cell development", "Negative regulation of cell differentiation", "Negative regulation of cell division", "Negative regulation of cell growth", "Negative regulation of cell growth involved in cardiac muscle cell development", "Negative regulation of cell junction assembly", "Negative regulation of cell killing", "Negative regulation of cell matrix adhesion", "Negative regulation of cell migration involved in sprouting angiogenesis", "Negative regulation of cell morphogenesis involved in differentiation", "Negative regulation of cell population proliferation", "Negative regulation of cell projection organization", "Negative regulation of cell size", "Negative regulation of cell substrate adhesion", "Negative regulation of cell substrate junction organization", "Negative regulation of cell volume", "Negative regulation of cellular amide metabolic process", "Negative regulation of cellular catabolic process", "Negative regulation of cellular component organization", "Negative regulation of cellular macromolecule biosynthetic process", "Negative regulation of cellular protein catabolic process", "Negative regulation of cellular respiration", "Negative regulation of cellular response to growth factor stimulus", "Negative regulation of cellular response to hypoxia", "Negative regulation of cellular response to insulin stimulus", "Negative regulation of cellular senescence", "Negative regulation of centriole replication", "Negative regulation of centrosome duplication", "Negative regulation of ceramide biosynthetic process", "Negative regulation of chemokine c c motif ligand 5 production", "Negative regulation of chemokine mediated signaling pathway", "Negative regulation of chemokine production", "Negative regulation of chemotaxis", "Negative regulation of cholesterol metabolic process", "Negative regulation of chondrocyte differentiation", "Negative regulation of chromatin binding", "Negative regulation of chromatin organization", "Negative regulation of chromosome organization", "Negative regulation of cilium assembly", "Negative regulation of circadian rhythm", "Negative regulation of coagulation", "Negative regulation of cold induced thermogenesis", "Negative regulation of collateral sprouting", "Negative regulation of cyclic nucleotide phosphodiesterase activity", "Negative regulation of cyclin dependent protein serine threonine kinase activity", "Negative regulation of cysteine type endopeptidase activity", "Negative regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Negative regulation of cytokine production", "Negative regulation of cytokine production involved in immune response", "Negative regulation of cytokine production involved in inflammatory response", "Negative regulation of cytokinesis", "Negative regulation of cytoplasmic translation", "Negative regulation of cytoskeleton organization", "Negative regulation of cytosolic calcium ion concentration", "Negative regulation of defense response", "Negative regulation of defense response to bacterium", "Negative regulation of defense response to virus", "Negative regulation of delayed rectifier potassium channel activity", "Negative regulation of dendrite development", "Negative regulation of dendrite morphogenesis", "Negative regulation of dendritic spine development", "Negative regulation of dendritic spine morphogenesis", "Negative regulation of dephosphorylation", "Negative regulation of developmental growth", "Negative regulation of developmental process", "Negative regulation of digestive system process", "Negative regulation of dna binding", "Negative regulation of dna binding transcription factor activity", "Negative regulation of dna biosynthetic process", "Negative regulation of dna damage checkpoint", "Negative regulation of dna damage response signal transduction by p53 class mediator", "Negative regulation of dna dependent dna replication", "Negative regulation of dna metabolic process", "Negative regulation of dna recombination", "Negative regulation of dna repair", "Negative regulation of dna replication", "Negative regulation of dna templated transcription elongation", "Negative regulation of dna templated transcription initiation", "Negative regulation of dopamine secretion", "Negative regulation of double strand break repair via homologous recombination", "Negative regulation of double strand break repair via nonhomologous end joining", "Negative regulation of endocytosis", "Negative regulation of endoplasmic reticulum calcium ion concentration", "Negative regulation of endoplasmic reticulum stress induced eif2 alpha phosphorylation", "Negative regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Negative regulation of endoplasmic reticulum unfolded protein response", "Negative regulation of endothelial cell apoptotic process", "Negative regulation of endothelial cell proliferation", "Negative regulation of epidermal growth factor activated receptor activity", "Negative regulation of epidermis development", "Negative regulation of epithelial cell apoptotic process", "Negative regulation of epithelial cell differentiation", "Negative regulation of epithelial cell migration", "Negative regulation of epithelial cell proliferation", "Negative regulation of erad pathway", "Negative regulation of erbb signaling pathway", "Negative regulation of erk1 and erk2 cascade", "Negative regulation of erythrocyte differentiation", "Negative regulation of establishment of protein localization", "Negative regulation of establishment of protein localization to mitochondrion", "Negative regulation of excitatory postsynaptic potential", "Negative regulation of execution phase of apoptosis", "Negative regulation of exocytosis", "Negative regulation of extrinsic apoptotic signaling pathway", "Negative regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Negative regulation of fat cell differentiation", "Negative regulation of fatty acid beta oxidation", "Negative regulation of fatty acid biosynthetic process", "Negative regulation of fatty acid metabolic process", "Negative regulation of fatty acid oxidation", "Negative regulation of fatty acid transport", "Negative regulation of feeding behavior", "Negative regulation of fibroblast apoptotic process", "Negative regulation of fibroblast migration", "Negative regulation of fibroblast proliferation", "Negative regulation of filopodium assembly", "Negative regulation of g protein coupled receptor signaling pathway", "Negative regulation of gene expression", "Negative regulation of gene expression epigenetic", "Negative regulation of glial cell apoptotic process", "Negative regulation of glial cell differentiation", "Negative regulation of glial cell proliferation", "Negative regulation of gliogenesis", "Negative regulation of glucocorticoid metabolic process", "Negative regulation of gluconeogenesis", "Negative regulation of glucose import", "Negative regulation of glucose transmembrane transport", "Negative regulation of glycogen metabolic process", "Negative regulation of glycolytic process", "Negative regulation of glycoprotein metabolic process", "Negative regulation of golgi to plasma membrane protein transport", "Negative regulation of granulocyte chemotaxis", "Negative regulation of growth", "Negative regulation of gtpase activity", "Negative regulation of guanyl nucleotide exchange factor activity", "Negative regulation of heart rate", "Negative regulation of helicase activity", "Negative regulation of hematopoietic progenitor cell differentiation", "Negative regulation of hemopoiesis", "Negative regulation of hepatocyte apoptotic process", "Negative regulation of high voltage gated calcium channel activity", "Negative regulation of hippo signaling", "Negative regulation of histone acetylation", "Negative regulation of histone deacetylation", "Negative regulation of histone h3 k27 methylation", "Negative regulation of histone h3 k4 methylation", "Negative regulation of histone h3 k9 methylation", "Negative regulation of histone h3 k9 trimethylation", "Negative regulation of histone h4 acetylation", "Negative regulation of histone methylation", "Negative regulation of histone modification", "Negative regulation of histone phosphorylation", "Negative regulation of homotypic cell cell adhesion", "Negative regulation of hormone biosynthetic process", "Negative regulation of hormone metabolic process", "Negative regulation of hormone secretion", "Negative regulation of hydrogen peroxide mediated programmed cell death", "Negative regulation of hydrolase activity", "Negative regulation of hypoxia induced intrinsic apoptotic signaling pathway", "Negative regulation of i kappab kinase nf kappab signaling", "Negative regulation of immune effector process", "Negative regulation of immune response", "Negative regulation of immune system process", "Negative regulation of immunoglobulin production", "Negative regulation of inclusion body assembly", "Negative regulation of inflammatory response", "Negative regulation of inflammatory response to antigenic stimulus", "Negative regulation of innate immune response", "Negative regulation of insulin secretion involved in cellular response to glucose stimulus", "Negative regulation of interferon beta production", "Negative regulation of interferon gamma production", "Negative regulation of interleukin 12 production", "Negative regulation of interleukin 13 production", "Negative regulation of interleukin 17 production", "Negative regulation of interleukin 2 production", "Negative regulation of interleukin 6 production", "Negative regulation of interleukin 8 production", "Negative regulation of intracellular estrogen receptor signaling pathway", "Negative regulation of intracellular protein transport", "Negative regulation of intracellular signal transduction", "Negative regulation of intracellular steroid hormone receptor signaling pathway", "Negative regulation of intracellular transport", "Negative regulation of intrinsic apoptotic signaling pathway", "Negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Negative regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Negative regulation of ion transmembrane transport", "Negative regulation of ion transmembrane transporter activity", "Negative regulation of ion transport", "Negative regulation of ire1 mediated unfolded protein response", "Negative regulation of isotype switching", "Negative regulation of jnk cascade", "Negative regulation of jun kinase activity", "Negative regulation of keratinocyte differentiation", "Negative regulation of keratinocyte proliferation", "Negative regulation of kidney development", "Negative regulation of kinase activity", "Negative regulation of lamellipodium assembly", "Negative regulation of lamellipodium organization", "Negative regulation of leukocyte apoptotic process", "Negative regulation of leukocyte cell cell adhesion", "Negative regulation of leukocyte chemotaxis", "Negative regulation of leukocyte degranulation", "Negative regulation of leukocyte mediated immunity", "Negative regulation of leukocyte migration", "Negative regulation of leukocyte proliferation", "Negative regulation of lipase activity", "Negative regulation of lipid biosynthetic process", "Negative regulation of lipid catabolic process", "Negative regulation of lipid kinase activity", "Negative regulation of lipid localization", "Negative regulation of lipid metabolic process", "Negative regulation of lipid storage", "Negative regulation of lipid transport", "Negative regulation of lipopolysaccharide mediated signaling pathway", "Negative regulation of lipoprotein lipase activity", "Negative regulation of lipoprotein particle clearance", "Negative regulation of locomotion", "Negative regulation of long term synaptic potentiation", "Negative regulation of low density lipoprotein particle clearance", "Negative regulation of low density lipoprotein receptor activity", "Negative regulation of lyase activity", "Negative regulation of lymphocyte activation", "Negative regulation of lymphocyte apoptotic process", "Negative regulation of lymphocyte differentiation", "Negative regulation of lymphocyte mediated immunity", "Negative regulation of lymphocyte migration", "Negative regulation of macroautophagy", "Negative regulation of macrophage activation", "Negative regulation of macrophage chemotaxis", "Negative regulation of macrophage migration", "Negative regulation of map kinase activity", "Negative regulation of mapk cascade", "Negative regulation of mast cell activation", "Negative regulation of mast cell activation involved in immune response", "Negative regulation of mast cell degranulation", "Negative regulation of megakaryocyte differentiation", "Negative regulation of meiotic cell cycle", "Negative regulation of meiotic nuclear division", "Negative regulation of membrane permeability", "Negative regulation of membrane potential", "Negative regulation of membrane protein ectodomain proteolysis", "Negative regulation of mesenchymal cell proliferation", "Negative regulation of metalloendopeptidase activity", "Negative regulation of metallopeptidase activity", "Negative regulation of metaphase anaphase transition of cell cycle", "Negative regulation of mhc class ii biosynthetic process", "Negative regulation of microglial cell activation", "Negative regulation of microtubule polymerization", "Negative regulation of microtubule polymerization or depolymerization", "Negative regulation of mirna transcription", "Negative regulation of mitochondrial fusion", "Negative regulation of mitochondrial membrane permeability", "Negative regulation of mitochondrial membrane permeability involved in apoptotic process", "Negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Negative regulation of mitochondrion organization", "Negative regulation of mitophagy", "Negative regulation of mitotic cell cycle", "Negative regulation of mitotic cell cycle phase transition", "Negative regulation of molecular function", "Negative regulation of monocyte chemotactic protein 1 production", "Negative regulation of monocyte chemotaxis", "Negative regulation of monocyte differentiation", "Negative regulation of mononuclear cell migration", "Negative regulation of monooxygenase activity", "Negative regulation of mrna 3 end processing", "Negative regulation of mrna catabolic process", "Negative regulation of mrna metabolic process", "Negative regulation of mrna processing", "Negative regulation of mrna splicing via spliceosome", "Negative regulation of multicellular organism growth", "Negative regulation of multicellular organismal process", "Negative regulation of muscle adaptation", "Negative regulation of muscle cell apoptotic process", "Negative regulation of muscle cell differentiation", "Negative regulation of muscle contraction", "Negative regulation of muscle hypertrophy", "Negative regulation of muscle organ development", "Negative regulation of muscle tissue development", "Negative regulation of myelination", "Negative regulation of myeloid cell apoptotic process", "Negative regulation of myeloid cell differentiation", "Negative regulation of myeloid leukocyte differentiation", "Negative regulation of myeloid leukocyte mediated immunity", "Negative regulation of myoblast differentiation", "Negative regulation of myosin light chain phosphatase activity", "Negative regulation of myotube differentiation", "Negative regulation of natural killer cell activation", "Negative regulation of natural killer cell mediated immunity", "Negative regulation of necrotic cell death", "Negative regulation of nervous system development", "Negative regulation of nervous system process", "Negative regulation of neural precursor cell proliferation", "Negative regulation of neuroblast proliferation", "Negative regulation of neuroinflammatory response", "Negative regulation of neuron apoptotic process", "Negative regulation of neuron death", "Negative regulation of neuron differentiation", "Negative regulation of neuron projection development", "Negative regulation of neuron projection regeneration", "Negative regulation of neurotransmitter secretion", "Negative regulation of neurotransmitter transport", "Negative regulation of neutrophil migration", "Negative regulation of nf kappab transcription factor activity", "Negative regulation of nik nf kappab signaling", "Negative regulation of nitric oxide metabolic process", "Negative regulation of nitric oxide synthase activity", "Negative regulation of nlrp3 inflammasome complex assembly", "Negative regulation of notch signaling pathway", "Negative regulation of nuclear division", "Negative regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Negative regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Negative regulation of nuclease activity", "Negative regulation of nucleobase containing compound metabolic process", "Negative regulation of nucleocytoplasmic transport", "Negative regulation of nucleotide biosynthetic process", "Negative regulation of nucleotide metabolic process", "Negative regulation of oligodendrocyte differentiation", "Negative regulation of organ growth", "Negative regulation of organelle assembly", "Negative regulation of organelle organization", "Negative regulation of organic acid transport", "Negative regulation of ossification", "Negative regulation of osteoblast differentiation", "Negative regulation of osteoblast proliferation", "Negative regulation of osteoclast differentiation", "Negative regulation of oxidative phosphorylation", "Negative regulation of oxidative stress induced cell death", "Negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Negative regulation of oxidative stress induced neuron death", "Negative regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway", "Negative regulation of oxidoreductase activity", "Negative regulation of p38mapk cascade", "Negative regulation of pathway restricted smad protein phosphorylation", "Negative regulation of peptidase activity", "Negative regulation of peptide secretion", "Negative regulation of peptidyl lysine acetylation", "Negative regulation of peptidyl serine phosphorylation", "Negative regulation of peptidyl threonine phosphorylation", "Negative regulation of peptidyl tyrosine phosphorylation", "Negative regulation of perk mediated unfolded protein response", "Negative regulation of phagocytosis", "Negative regulation of phosphatase activity", "Negative regulation of phosphatidylinositol 3 kinase signaling", "Negative regulation of phospholipase activity", "Negative regulation of phospholipid metabolic process", "Negative regulation of phosphoprotein phosphatase activity", "Negative regulation of phosphorus metabolic process", "Negative regulation of phosphorylation", "Negative regulation of plasma membrane bounded cell projection assembly", "Negative regulation of platelet activation", "Negative regulation of platelet derived growth factor receptor signaling pathway", "Negative regulation of posttranscriptional gene silencing", "Negative regulation of potassium ion transmembrane transport", "Negative regulation of potassium ion transport", "Negative regulation of production of mirnas involved in gene silencing by mirna", "Negative regulation of production of molecular mediator of immune response", "Negative regulation of programmed necrotic cell death", "Negative regulation of prostaglandin biosynthetic process", "Negative regulation of proteasomal protein catabolic process", "Negative regulation of proteasomal ubiquitin dependent protein catabolic process", "Negative regulation of protein acetylation", "Negative regulation of protein autophosphorylation", "Negative regulation of protein binding", "Negative regulation of protein catabolic process", "Negative regulation of protein containing complex assembly", "Negative regulation of protein containing complex disassembly", "Negative regulation of protein dephosphorylation", "Negative regulation of protein exit from endoplasmic reticulum", "Negative regulation of protein export from nucleus", "Negative regulation of protein import into nucleus", "Negative regulation of protein k63 linked ubiquitination", "Negative regulation of protein kinase activity by regulation of protein phosphorylation", "Negative regulation of protein kinase b signaling", "Negative regulation of protein localization", "Negative regulation of protein localization to cell periphery", "Negative regulation of protein localization to cell surface", "Negative regulation of protein localization to membrane", "Negative regulation of protein localization to microtubule", "Negative regulation of protein localization to nucleus", "Negative regulation of protein maturation", "Negative regulation of protein metabolic process", "Negative regulation of protein modification by small protein conjugation or removal", "Negative regulation of protein modification process", "Negative regulation of protein polymerization", "Negative regulation of protein polyubiquitination", "Negative regulation of protein secretion", "Negative regulation of protein serine threonine kinase activity", "Negative regulation of protein sumoylation", "Negative regulation of protein targeting to membrane", "Negative regulation of protein targeting to mitochondrion", "Negative regulation of protein tyrosine kinase activity", "Negative regulation of proteolysis", "Negative regulation of proteolysis involved in cellular protein catabolic process", "Negative regulation of reactive oxygen species biosynthetic process", "Negative regulation of reactive oxygen species metabolic process", "Negative regulation of receptor binding", "Negative regulation of receptor internalization", "Negative regulation of receptor mediated endocytosis", "Negative regulation of receptor recycling", "Negative regulation of receptor signaling pathway via jak stat", "Negative regulation of receptor signaling pathway via stat", "Negative regulation of regulated secretory pathway", "Negative regulation of release of cytochrome c from mitochondria", "Negative regulation of reproductive process", "Negative regulation of respiratory burst", "Negative regulation of respiratory burst involved in inflammatory response", "Negative regulation of response to biotic stimulus", "Negative regulation of response to cytokine stimulus", "Negative regulation of response to dna damage stimulus", "Negative regulation of response to endoplasmic reticulum stress", "Negative regulation of response to external stimulus", "Negative regulation of response to food", "Negative regulation of response to oxidative stress", "Negative regulation of response to reactive oxygen species", "Negative regulation of response to stimulus", "Negative regulation of response to wounding", "Negative regulation of retinoic acid receptor signaling pathway", "Negative regulation of rho protein signal transduction", "Negative regulation of rig i signaling pathway", "Negative regulation of rna catabolic process", "Negative regulation of rna splicing", "Negative regulation of ruffle assembly", "Negative regulation of ryanodine sensitive calcium release channel activity", "Negative regulation of schwann cell proliferation", "Negative regulation of secondary metabolite biosynthetic process", "Negative regulation of secretion", "Negative regulation of sequestering of triglyceride", "Negative regulation of signal transduction by p53 class mediator", "Negative regulation of signal transduction in absence of ligand", "Negative regulation of signaling", "Negative regulation of signaling receptor activity", "Negative regulation of single stranded viral rna replication via double stranded dna intermediate", "Negative regulation of sister chromatid cohesion", "Negative regulation of smad protein signal transduction", "Negative regulation of small gtpase mediated signal transduction", "Negative regulation of small molecule metabolic process", "Negative regulation of smooth muscle cell apoptotic process", "Negative regulation of smooth muscle cell differentiation", "Negative regulation of smooth muscle cell migration", "Negative regulation of smooth muscle cell proliferation", "Negative regulation of smoothened signaling pathway", "Negative regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Negative regulation of sodium ion transmembrane transport", "Negative regulation of sodium ion transport", "Negative regulation of sphingolipid biosynthetic process", "Negative regulation of sprouting angiogenesis", "Negative regulation of stem cell differentiation", "Negative regulation of steroid metabolic process", "Negative regulation of stress activated protein kinase signaling cascade", "Negative regulation of striated muscle cell apoptotic process", "Negative regulation of striated muscle cell differentiation", "Negative regulation of striated muscle contraction", "Negative regulation of supramolecular fiber organization", "Negative regulation of synapse assembly", "Negative regulation of synapse organization", "Negative regulation of synaptic transmission", "Negative regulation of synaptic transmission glutamatergic", "Negative regulation of synaptic vesicle exocytosis", "Negative regulation of systemic arterial blood pressure", "Negative regulation of t cell apoptotic process", "Negative regulation of t cell differentiation", "Negative regulation of t cell proliferation", "Negative regulation of t cell receptor signaling pathway", "Negative regulation of t helper cell differentiation", "Negative regulation of telomerase activity", "Negative regulation of telomere capping", "Negative regulation of telomere maintenance", "Negative regulation of telomere maintenance via telomerase", "Negative regulation of telomere maintenance via telomere lengthening", "Negative regulation of thymocyte apoptotic process", "Negative regulation of tissue remodeling", "Negative regulation of toll like receptor 2 signaling pathway", "Negative regulation of toll like receptor 4 signaling pathway", "Negative regulation of toll like receptor signaling pathway", "Negative regulation of tor signaling", "Negative regulation of transcription by competitive promoter binding", "Negative regulation of transcription by rna polymerase i", "Negative regulation of transcription by rna polymerase ii", "Negative regulation of transcription from rna polymerase ii promoter in response to stress", "Negative regulation of transcription initiation from rna polymerase ii promoter", "Negative regulation of transcription regulatory region dna binding", "Negative regulation of transferase activity", "Negative regulation of transforming growth factor beta production", "Negative regulation of transforming growth factor beta receptor signaling pathway", "Negative regulation of transforming growth factor beta1 production", "Negative regulation of translational elongation", "Negative regulation of translational initiation", "Negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Negative regulation of transmembrane transport", "Negative regulation of transport", "Negative regulation of transporter activity", "Negative regulation of trophoblast cell migration", "Negative regulation of tubulin deacetylation", "Negative regulation of tumor necrosis factor superfamily cytokine production", "Negative regulation of type 2 immune response", "Negative regulation of type b pancreatic cell apoptotic process", "Negative regulation of type i interferon mediated signaling pathway", "Negative regulation of type i interferon production", "Negative regulation of tyrosine phosphorylation of stat protein", "Negative regulation of ubiquitin dependent protein catabolic process", "Negative regulation of ubiquitin protein ligase activity", "Negative regulation of ubiquitin protein transferase activity", "Negative regulation of vascular associated smooth muscle cell apoptotic process", "Negative regulation of vascular associated smooth muscle cell differentiation", "Negative regulation of vascular associated smooth muscle cell migration", "Negative regulation of vascular associated smooth muscle cell proliferation", "Negative regulation of vascular endothelial growth factor production", "Negative regulation of vascular endothelial growth factor receptor signaling pathway", "Negative regulation of vascular permeability", "Negative regulation of vascular wound healing", "Negative regulation of vasculature development", "Negative regulation of viral entry into host cell", "Negative regulation of viral genome replication", "Negative regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Negative regulation of viral life cycle", "Negative regulation of viral process", "Negative regulation of viral transcription", "Negative regulation of vitamin metabolic process", "Negative regulation of voltage gated calcium channel activity", "Negative regulation of voltage gated potassium channel activity", "Negative regulation of wnt signaling pathway", "Negative regulation of wound healing", "Nephric duct development", "Nephric duct morphogenesis", "Nephron development", "Nephron epithelium development", "Nephron morphogenesis", "Nephron tubule epithelial cell differentiation", "Nephron tubule formation", "Nerve development", "Nerve growth factor signaling pathway", "Nervous system process", "Nervous system process involved in regulation of systemic arterial blood pressure", "Netrin activated signaling pathway", "Neural crest cell differentiation", "Neural crest cell migration", "Neural crest cell migration involved in autonomic nervous system development", "Neural crest formation", "Neural fold formation", "Neural nucleus development", "Neural plate development", "Neural plate morphogenesis", "Neural precursor cell proliferation", "Neural retina development", "Neural tube development", "Neural tube formation", "Neural tube patterning", "Neuroblast division", "Neuroblast proliferation", "Neuroendocrine cell differentiation", "Neuroepithelial cell differentiation", "Neurofilament cytoskeleton organization", "Neurogenesis", "Neuroinflammatory response", "Neuromuscular junction development", "Neuromuscular process", "Neuromuscular process controlling balance", "Neuromuscular process controlling posture", "Neuromuscular synaptic transmission", "Neuron apoptotic process", "Neuron cellular homeostasis", "Neuron death", "Neuron death in response to hydrogen peroxide", "Neuron death in response to oxidative stress", "Neuron development", "Neuron differentiation", "Neuron fate commitment", "Neuron fate determination", "Neuron fate specification", "Neuron intrinsic apoptotic signaling pathway in response to oxidative stress", "Neuron maturation", "Neuron migration", "Neuron neuron synaptic transmission", "Neuron projection arborization", "Neuron projection extension", "Neuron projection extension involved in neuron projection guidance", "Neuron projection guidance", "Neuron projection maintenance", "Neuron projection organization", "Neuron projection regeneration", "Neuron recognition", "Neuron remodeling", "Neuronal action potential", "Neuronal ion channel clustering", "Neuronal signal transduction", "Neuronal stem cell population maintenance", "Neuropeptide signaling pathway", "Neurotransmitter biosynthetic process", "Neurotransmitter catabolic process", "Neurotransmitter gated ion channel clustering", "Neurotransmitter metabolic process", "Neurotransmitter receptor internalization", "Neurotransmitter receptor localization to postsynaptic specialization membrane", "Neurotransmitter receptor transport", "Neurotransmitter receptor transport endosome to postsynaptic membrane", "Neurotransmitter receptor transport postsynaptic endosome to lysosome", "Neurotransmitter receptor transport to plasma membrane", "Neurotransmitter reuptake", "Neurotransmitter secretion", "Neurotransmitter transport", "Neurotransmitter uptake", "Neurotrophin production", "Neurotrophin signaling pathway", "Neurotrophin trk receptor signaling pathway", "Neutral amino acid transport", "Neutral lipid biosynthetic process", "Neutral lipid catabolic process", "Neutral lipid metabolic process", "Neutrophil activation involved in immune response", "Neutrophil apoptotic process", "Neutrophil chemotaxis", "Neutrophil clearance", "Neutrophil degranulation", "Neutrophil differentiation", "Neutrophil homeostasis", "Neutrophil mediated immunity", "Neutrophil migration", "Nik nf kappab signaling", "Nitric oxide mediated signal transduction", "Nitric oxide synthase biosynthetic process", "Nitrogen compound transport", "Nitrogen utilization", "Nk t cell activation", "Nk t cell differentiation", "Nls bearing protein import into nucleus", "Non canonical wnt signaling pathway", "Non lytic viral release", "Non membrane bounded organelle assembly", "Non motile cilium assembly", "Nonribosomal peptide biosynthetic process", "Nose development", "Notch receptor processing", "Notch signaling involved in heart development", "Notch signaling pathway", "Nuclear body organization", "Nuclear chromosome segregation", "Nuclear envelope organization", "Nuclear export", "Nuclear membrane organization", "Nuclear membrane reassembly", "Nuclear migration", "Nuclear ncrna surveillance", "Nuclear pore complex assembly", "Nuclear pore organization", "Nuclear transcribed mrna catabolic process", "Nuclear transcribed mrna catabolic process deadenylation dependent decay", "Nuclear transcribed mrna catabolic process deadenylation independent decay", "Nuclear transcribed mrna catabolic process exonucleolytic", "Nuclear transcribed mrna catabolic process exonucleolytic 3 5", "Nuclear transcribed mrna catabolic process nonsense mediated decay", "Nuclear transcribed mrna poly a tail shortening", "Nuclear transport", "Nucleic acid phosphodiester bond hydrolysis", "Nucleobase biosynthetic process", "Nucleobase catabolic process", "Nucleobase containing compound transport", "Nucleobase containing small molecule biosynthetic process", "Nucleobase containing small molecule catabolic process", "Nucleobase containing small molecule interconversion", "Nucleobase containing small molecule metabolic process", "Nucleobase metabolic process", "Nucleobase transport", "Nucleolar chromatin organization", "Nucleolar large rrna transcription by rna polymerase i", "Nucleolus organization", "Nucleoside bisphosphate biosynthetic process", "Nucleoside bisphosphate catabolic process", "Nucleoside bisphosphate metabolic process", "Nucleoside catabolic process", "Nucleoside diphosphate biosynthetic process", "Nucleoside diphosphate catabolic process", "Nucleoside diphosphate metabolic process", "Nucleoside metabolic process", "Nucleoside monophosphate biosynthetic process", "Nucleoside monophosphate catabolic process", "Nucleoside monophosphate metabolic process", "Nucleoside monophosphate phosphorylation", "Nucleoside phosphate biosynthetic process", "Nucleoside phosphate catabolic process", "Nucleoside salvage", "Nucleoside transmembrane transport", "Nucleoside transport", "Nucleoside triphosphate biosynthetic process", "Nucleoside triphosphate catabolic process", "Nucleoside triphosphate metabolic process", "Nucleosome assembly", "Nucleosome mobilization", "Nucleosome organization", "Nucleosome positioning", "Nucleotide binding domain leucine rich repeat containing receptor signaling pathway", "Nucleotide binding oligomerization domain containing 2 signaling pathway", "Nucleotide excision repair", "Nucleotide excision repair dna gap filling", "Nucleotide excision repair dna incision", "Nucleotide phosphorylation", "Nucleotide salvage", "Nucleotide sugar biosynthetic process", "Nucleotide sugar metabolic process", "Nucleotide sugar transmembrane transport", "Nucleotide transmembrane transport", "Nucleotide transport", "Nucleus localization", "Nucleus organization", "O glycan processing", "Observational learning", "Odontoblast differentiation", "Odontogenesis", "Odontogenesis of dentin containing tooth", "Olefinic compound biosynthetic process", "Olefinic compound metabolic process", "Olfactory behavior", "Olfactory bulb interneuron development", "Olfactory bulb interneuron differentiation", "Olfactory lobe development", "Oligodendrocyte development", "Oligodendrocyte differentiation", "Oligodendrocyte progenitor proliferation", "Oligopeptide transport", "Oligosaccharide catabolic process", "Oligosaccharide lipid intermediate biosynthetic process", "Oligosaccharide metabolic process", "One carbon metabolic process", "Oocyte construction", "Oocyte differentiation", "Oocyte maturation", "Oogenesis", "Opsonization", "Optic nerve development", "Organ growth", "Organ induction", "Organ or tissue specific immune response", "Organelle assembly", "Organelle disassembly", "Organelle fission", "Organelle fusion", "Organelle inheritance", "Organelle localization", "Organelle membrane fusion", "Organelle transport along microtubule", "Organic acid biosynthetic process", "Organic acid catabolic process", "Organic acid metabolic process", "Organic acid transmembrane transport", "Organic acid transport", "Organic anion transport", "Organic cation transport", "Organic cyclic compound catabolic process", "Organic hydroxy compound biosynthetic process", "Organic hydroxy compound catabolic process", "Organic hydroxy compound metabolic process", "Organic hydroxy compound transport", "Organism emergence from protective structure", "Organonitrogen compound biosynthetic process", "Organonitrogen compound catabolic process", "Organophosphate biosynthetic process", "Organophosphate catabolic process", "Organophosphate ester transport", "Organophosphate metabolic process", "Ornithine metabolic process", "Ornithine transport", "Ossification", "Osteoblast development", "Osteoblast differentiation", "Osteoblast proliferation", "Osteoclast development", "Osteoclast differentiation", "Osteoclast fusion", "Otolith development", "Outer dynein arm assembly", "Outer ear morphogenesis", "Outer mitochondrial membrane organization", "Outflow tract morphogenesis", "Outflow tract septum morphogenesis", "Ovarian follicle development", "Oviduct development", "Ovulation", "Ovulation cycle", "Ovulation cycle process", "Ovulation from ovarian follicle", "Oxaloacetate metabolic process", "Oxaloacetate transport", "Oxidative demethylation", "Oxidative dna demethylation", "Oxidative phosphorylation", "Oxidative rna demethylation", "Oxygen homeostasis", "P body assembly", "P38mapk cascade", "Pallium development", "Pancreas development", "Pancreatic juice secretion", "Pantothenate metabolic process", "Parallel actin filament bundle assembly", "Paranodal junction assembly", "Parasympathetic nervous system development", "Parathyroid gland development", "Paraxial mesoderm development", "Paraxial mesoderm formation", "Paraxial mesoderm morphogenesis", "Pathway restricted smad protein phosphorylation", "Pattern recognition receptor signaling pathway", "Pattern specification involved in kidney development", "Pattern specification process", "Penetration of zona pellucida", "Penile erection", "Pentose catabolic process", "Pentose metabolic process", "Pentose phosphate shunt", "Pentose phosphate shunt non oxidative branch", "Peptide antigen assembly with mhc protein complex", "Peptide biosynthetic process", "Peptide catabolic process", "Peptide cross linking", "Peptide metabolic process", "Peptide modification", "Peptide transport", "Peptidyl amino acid modification", "Peptidyl arginine methylation", "Peptidyl arginine methylation to asymmetrical dimethyl arginine", "Peptidyl arginine modification", "Peptidyl arginine n methylation", "Peptidyl asparagine modification", "Peptidyl cysteine modification", "Peptidyl diphthamide biosynthetic process from peptidyl histidine", "Peptidyl glutamic acid modification", "Peptidyl glutamine methylation", "Peptidyl histidine modification", "Peptidyl lysine acetylation", "Peptidyl lysine deacetylation", "Peptidyl lysine dimethylation", "Peptidyl lysine hydroxylation", "Peptidyl lysine methylation", "Peptidyl lysine modification", "Peptidyl lysine monomethylation", "Peptidyl lysine trimethylation", "Peptidyl methionine modification", "Peptidyl proline hydroxylation", "Peptidyl proline hydroxylation to 4 hydroxy l proline", "Peptidyl proline modification", "Peptidyl serine autophosphorylation", "Peptidyl serine dephosphorylation", "Peptidyl serine modification", "Peptidyl threonine dephosphorylation", "Peptidyl threonine modification", "Peptidyl tyrosine autophosphorylation", "Peptidyl tyrosine dephosphorylation", "Peptidyl tyrosine dephosphorylation involved in inactivation of protein kinase activity", "Peptidyl tyrosine modification", "Pericyte cell differentiation", "Peripheral nervous system axon regeneration", "Peripheral nervous system development", "Peripheral nervous system myelin maintenance", "Peristalsis", "Perk mediated unfolded protein response", "Peroxisomal transport", "Peroxisome fission", "Peroxisome organization", "Peroxisome proliferator activated receptor signaling pathway", "Ph reduction", "Phagocytosis", "Phagocytosis recognition", "Phagolysosome assembly", "Phagosome acidification", "Phagosome lysosome fusion", "Phagosome maturation", "Pharyngeal system development", "Phasic smooth muscle contraction", "Phenol containing compound biosynthetic process", "Phenol containing compound catabolic process", "Phenol containing compound metabolic process", "Phenotypic switching", "Phosphagen metabolic process", "Phosphate ion transmembrane transport", "Phosphate ion transport", "Phosphatidic acid metabolic process", "Phosphatidylcholine acyl chain remodeling", "Phosphatidylcholine biosynthetic process", "Phosphatidylcholine catabolic process", "Phosphatidylcholine metabolic process", "Phosphatidylethanolamine biosynthetic process", "Phosphatidylethanolamine metabolic process", "Phosphatidylglycerol acyl chain remodeling", "Phosphatidylglycerol biosynthetic process", "Phosphatidylglycerol metabolic process", "Phosphatidylinositol 3 kinase signaling", "Phosphatidylinositol 3 phosphate biosynthetic process", "Phosphatidylinositol acyl chain remodeling", "Phosphatidylinositol biosynthetic process", "Phosphatidylinositol dephosphorylation", "Phosphatidylinositol metabolic process", "Phosphatidylinositol phosphate biosynthetic process", "Phosphatidylserine acyl chain remodeling", "Phosphatidylserine metabolic process", "Phospholipase c activating g protein coupled receptor signaling pathway", "Phospholipid biosynthetic process", "Phospholipid catabolic process", "Phospholipid dephosphorylation", "Phospholipid homeostasis", "Phospholipid metabolic process", "Phospholipid transport", "Phosphorylation", "Phosphorylation of rna polymerase ii c terminal domain", "Photoperiodism", "Photoreceptor cell development", "Photoreceptor cell differentiation", "Photoreceptor cell maintenance", "Photoreceptor cell outer segment organization", "Phototransduction", "Phototransduction visible light", "Physiological cardiac muscle hypertrophy", "Pigment accumulation", "Pigment biosynthetic process", "Pigment cell differentiation", "Pigment granule localization", "Pigment granule maturation", "Pigment granule organization", "Pigment metabolic process", "Pigmentation", "Pinocytosis", "Pirna metabolic process", "Pituitary gland development", "Placenta blood vessel development", "Placenta development", "Planar cell polarity pathway involved in neural tube closure", "Plasma lipoprotein particle clearance", "Plasma membrane fusion", "Plasma membrane organization", "Plasma membrane phospholipid scrambling", "Plasma membrane raft assembly", "Plasma membrane raft organization", "Plasma membrane repair", "Plasma membrane to endosome transport", "Plasma membrane tubulation", "Plasminogen activation", "Platelet activating factor metabolic process", "Platelet activation", "Platelet aggregation", "Platelet degranulation", "Platelet derived growth factor receptor alpha signaling pathway", "Platelet derived growth factor receptor beta signaling pathway", "Platelet derived growth factor receptor signaling pathway", "Platelet morphogenesis", "Plus end directed organelle transport along microtubule", "Pml body organization", "Podosome assembly", "Pointed end actin filament capping", "Polarized epithelial cell differentiation", "Poly a plus mrna export from nucleus", "Poly n acetyllactosamine metabolic process", "Polyadenylation dependent rna catabolic process", "Polyadenylation dependent snorna 3 end processing", "Polyamine biosynthetic process", "Polyamine metabolic process", "Polyamine transport", "Polyketide metabolic process", "Polyol biosynthetic process", "Polyol catabolic process", "Polyol metabolic process", "Polyprenol metabolic process", "Polysaccharide biosynthetic process", "Polysaccharide catabolic process", "Polysaccharide metabolic process", "Pons development", "Pore complex assembly", "Porphyrin containing compound metabolic process", "Positive chemotaxis", "Positive regulation by host of viral genome replication", "Positive regulation by host of viral process", "Positive regulation by host of viral transcription", "Positive regulation by symbiont of entry into host", "Positive regulation of 3 utr mediated mrna stabilization", "Positive regulation of actin cytoskeleton reorganization", "Positive regulation of actin filament bundle assembly", "Positive regulation of actin filament depolymerization", "Positive regulation of actin filament polymerization", "Positive regulation of actin nucleation", "Positive regulation of action potential", "Positive regulation of activated t cell proliferation", "Positive regulation of activin receptor signaling pathway", "Positive regulation of acute inflammatory response", "Positive regulation of acute inflammatory response to antigenic stimulus", "Positive regulation of adaptive immune response", "Positive regulation of adipose tissue development", "Positive regulation of alcohol biosynthetic process", "Positive regulation of alpha beta t cell activation", "Positive regulation of alpha beta t cell differentiation", "Positive regulation of alpha beta t cell proliferation", "Positive regulation of amine transport", "Positive regulation of amino acid transport", "Positive regulation of amyloid beta clearance", "Positive regulation of amyloid beta formation", "Positive regulation of amyloid precursor protein biosynthetic process", "Positive regulation of amyloid precursor protein catabolic process", "Positive regulation of animal organ morphogenesis", "Positive regulation of anion transmembrane transport", "Positive regulation of anion transport", "Positive regulation of anoikis", "Positive regulation of antigen receptor mediated signaling pathway", "Positive regulation of apoptotic dna fragmentation", "Positive regulation of apoptotic process involved in development", "Positive regulation of apoptotic process involved in morphogenesis", "Positive regulation of apoptotic signaling pathway", "Positive regulation of arp2 3 complex mediated actin nucleation", "Positive regulation of aspartic type peptidase activity", "Positive regulation of astrocyte differentiation", "Positive regulation of atp biosynthetic process", "Positive regulation of atp dependent activity", "Positive regulation of atp metabolic process", "Positive regulation of atpase coupled calcium transmembrane transporter activity", "Positive regulation of attachment of spindle microtubules to kinetochore", "Positive regulation of autophagy", "Positive regulation of autophagy of mitochondrion", "Positive regulation of axon extension", "Positive regulation of axon extension involved in axon guidance", "Positive regulation of axonogenesis", "Positive regulation of b cell activation", "Positive regulation of b cell differentiation", "Positive regulation of b cell mediated immunity", "Positive regulation of b cell proliferation", "Positive regulation of basement membrane assembly involved in embryonic body morphogenesis", "Positive regulation of behavior", "Positive regulation of binding", "Positive regulation of biomineralization", "Positive regulation of blood brain barrier permeability", "Positive regulation of blood circulation", "Positive regulation of blood pressure", "Positive regulation of blood pressure by epinephrine norepinephrine", "Positive regulation of blood vessel endothelial cell migration", "Positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Positive regulation of bmp signaling pathway", "Positive regulation of bone mineralization", "Positive regulation of bone resorption", "Positive regulation of brown fat cell differentiation", "Positive regulation of calcineurin mediated signaling", "Positive regulation of calcium ion dependent exocytosis", "Positive regulation of calcium ion import", "Positive regulation of calcium ion transmembrane transport", "Positive regulation of calcium ion transmembrane transporter activity", "Positive regulation of calcium ion transport", "Positive regulation of calcium ion transport into cytosol", "Positive regulation of calcium mediated signaling", "Positive regulation of camp dependent protein kinase activity", "Positive regulation of camp mediated signaling", "Positive regulation of canonical wnt signaling pathway", "Positive regulation of carbohydrate metabolic process", "Positive regulation of cardiac muscle adaptation", "Positive regulation of cardiac muscle cell proliferation", "Positive regulation of cardioblast differentiation", "Positive regulation of cardiocyte differentiation", "Positive regulation of cartilage development", "Positive regulation of catabolic process", "Positive regulation of catalytic activity", "Positive regulation of catecholamine metabolic process", "Positive regulation of cation channel activity", "Positive regulation of cd4 positive alpha beta t cell activation", "Positive regulation of cd4 positive alpha beta t cell differentiation", "Positive regulation of cd8 positive alpha beta t cell activation", "Positive regulation of cell activation", "Positive regulation of cell adhesion", "Positive regulation of cell adhesion mediated by integrin", "Positive regulation of cell adhesion molecule production", "Positive regulation of cell aging", "Positive regulation of cell cell adhesion", "Positive regulation of cell cell adhesion mediated by cadherin", "Positive regulation of cell cycle", "Positive regulation of cell cycle checkpoint", "Positive regulation of cell cycle g1 s phase transition", "Positive regulation of cell cycle g2 m phase transition", "Positive regulation of cell cycle phase transition", "Positive regulation of cell cycle process", "Positive regulation of cell death", "Positive regulation of cell development", "Positive regulation of cell differentiation", "Positive regulation of cell division", "Positive regulation of cell growth", "Positive regulation of cell growth involved in cardiac muscle cell development", "Positive regulation of cell junction assembly", "Positive regulation of cell killing", "Positive regulation of cell matrix adhesion", "Positive regulation of cell maturation", "Positive regulation of cell migration by vascular endothelial growth factor signaling pathway", "Positive regulation of cell migration involved in sprouting angiogenesis", "Positive regulation of cell morphogenesis involved in differentiation", "Positive regulation of cell population proliferation", "Positive regulation of cell projection organization", "Positive regulation of cell proliferation involved in heart morphogenesis", "Positive regulation of cell size", "Positive regulation of cell substrate adhesion", "Positive regulation of cell substrate junction organization", "Positive regulation of cellular amide metabolic process", "Positive regulation of cellular amine metabolic process", "Positive regulation of cellular biosynthetic process", "Positive regulation of cellular carbohydrate metabolic process", "Positive regulation of cellular component biogenesis", "Positive regulation of cellular component organization", "Positive regulation of cellular extravasation", "Positive regulation of cellular ph reduction", "Positive regulation of cellular protein catabolic process", "Positive regulation of cellular respiration", "Positive regulation of cellular response to insulin stimulus", "Positive regulation of cellular response to transforming growth factor beta stimulus", "Positive regulation of centriole replication", "Positive regulation of chemokine c c motif ligand 5 production", "Positive regulation of chemokine c x c motif ligand 2 production", "Positive regulation of chemokine production", "Positive regulation of chemotaxis", "Positive regulation of cholesterol biosynthetic process", "Positive regulation of cholesterol efflux", "Positive regulation of cholesterol metabolic process", "Positive regulation of cholesterol storage", "Positive regulation of chondrocyte differentiation", "Positive regulation of chromatin binding", "Positive regulation of chromatin organization", "Positive regulation of chromosome condensation", "Positive regulation of chromosome organization", "Positive regulation of chromosome segregation", "Positive regulation of chromosome separation", "Positive regulation of cilium assembly", "Positive regulation of circadian rhythm", "Positive regulation of clathrin dependent endocytosis", "Positive regulation of coagulation", "Positive regulation of cold induced thermogenesis", "Positive regulation of collagen metabolic process", "Positive regulation of collateral sprouting", "Positive regulation of complement activation", "Positive regulation of connective tissue replacement", "Positive regulation of cyclase activity", "Positive regulation of cyclic nucleotide phosphodiesterase activity", "Positive regulation of cyclin dependent protein kinase activity", "Positive regulation of cysteine type endopeptidase activity", "Positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Positive regulation of cytokine production", "Positive regulation of cytokine production involved in immune response", "Positive regulation of cytokine production involved in inflammatory response", "Positive regulation of cytokinesis", "Positive regulation of cytoplasmic translation", "Positive regulation of cytoplasmic transport", "Positive regulation of cytoskeleton organization", "Positive regulation of defense response", "Positive regulation of defense response to virus by host", "Positive regulation of dendrite development", "Positive regulation of dendrite morphogenesis", "Positive regulation of dendritic cell cytokine production", "Positive regulation of dendritic cell differentiation", "Positive regulation of dendritic spine development", "Positive regulation of dendritic spine morphogenesis", "Positive regulation of deoxyribonuclease activity", "Positive regulation of dephosphorylation", "Positive regulation of developmental growth", "Positive regulation of developmental pigmentation", "Positive regulation of developmental process", "Positive regulation of dna binding", "Positive regulation of dna binding transcription factor activity", "Positive regulation of dna biosynthetic process", "Positive regulation of dna catabolic process", "Positive regulation of dna damage response signal transduction by p53 class mediator", "Positive regulation of dna demethylation", "Positive regulation of dna dependent dna replication", "Positive regulation of dna ligation", "Positive regulation of dna metabolic process", "Positive regulation of dna methylation dependent heterochromatin assembly", "Positive regulation of dna recombination", "Positive regulation of dna repair", "Positive regulation of dna replication", "Positive regulation of dna templated transcription elongation", "Positive regulation of dna templated transcription initiation", "Positive regulation of dopamine receptor signaling pathway", "Positive regulation of double strand break repair", "Positive regulation of double strand break repair via homologous recombination", "Positive regulation of double strand break repair via nonhomologous end joining", "Positive regulation of early endosome to late endosome transport", "Positive regulation of embryonic development", "Positive regulation of endocytic recycling", "Positive regulation of endocytosis", "Positive regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Positive regulation of endoplasmic reticulum unfolded protein response", "Positive regulation of endothelial cell apoptotic process", "Positive regulation of endothelial cell chemotaxis", "Positive regulation of endothelial cell chemotaxis by vegf activated vascular endothelial growth factor receptor signaling pathway", "Positive regulation of endothelial cell development", "Positive regulation of endothelial cell differentiation", "Positive regulation of endothelial cell matrix adhesion via fibronectin", "Positive regulation of endothelial cell migration", "Positive regulation of endothelial cell proliferation", "Positive regulation of epidermal cell differentiation", "Positive regulation of epidermal growth factor activated receptor activity", "Positive regulation of epidermis development", "Positive regulation of epithelial cell apoptotic process", "Positive regulation of epithelial cell differentiation", "Positive regulation of epithelial cell migration", "Positive regulation of epithelial cell proliferation", "Positive regulation of epithelial cell proliferation involved in lung morphogenesis", "Positive regulation of epithelial to mesenchymal transition", "Positive regulation of er associated ubiquitin dependent protein catabolic process", "Positive regulation of erad pathway", "Positive regulation of erbb signaling pathway", "Positive regulation of erk1 and erk2 cascade", "Positive regulation of erythrocyte differentiation", "Positive regulation of establishment of protein localization", "Positive regulation of establishment of protein localization to mitochondrion", "Positive regulation of establishment of protein localization to telomere", "Positive regulation of excitatory postsynaptic potential", "Positive regulation of execution phase of apoptosis", "Positive regulation of exocytosis", "Positive regulation of exosomal secretion", "Positive regulation of extracellular matrix assembly", "Positive regulation of extracellular matrix disassembly", "Positive regulation of extracellular matrix organization", "Positive regulation of extrinsic apoptotic signaling pathway", "Positive regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Positive regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Positive regulation of fat cell differentiation", "Positive regulation of fatty acid beta oxidation", "Positive regulation of fatty acid biosynthetic process", "Positive regulation of fatty acid metabolic process", "Positive regulation of fatty acid oxidation", "Positive regulation of fatty acid transport", "Positive regulation of fc receptor mediated stimulatory signaling pathway", "Positive regulation of feeding behavior", "Positive regulation of fibroblast growth factor receptor signaling pathway", "Positive regulation of fibroblast migration", "Positive regulation of fibroblast proliferation", "Positive regulation of filopodium assembly", "Positive regulation of focal adhesion assembly", "Positive regulation of g protein coupled receptor signaling pathway", "Positive regulation of g0 to g1 transition", "Positive regulation of g1 s transition of mitotic cell cycle", "Positive regulation of gastrulation", "Positive regulation of gene expression", "Positive regulation of glial cell differentiation", "Positive regulation of glial cell migration", "Positive regulation of glial cell proliferation", "Positive regulation of gliogenesis", "Positive regulation of glucokinase activity", "Positive regulation of gluconeogenesis", "Positive regulation of glucose import", "Positive regulation of glucose metabolic process", "Positive regulation of glucose transmembrane transport", "Positive regulation of glutamate secretion", "Positive regulation of glycogen metabolic process", "Positive regulation of glycolytic process", "Positive regulation of glycoprotein metabolic process", "Positive regulation of golgi to plasma membrane protein transport", "Positive regulation of gonad development", "Positive regulation of granulocyte chemotaxis", "Positive regulation of granulocyte differentiation", "Positive regulation of growth", "Positive regulation of gtpase activity", "Positive regulation of hair follicle development", "Positive regulation of heart growth", "Positive regulation of heart rate", "Positive regulation of heat generation", "Positive regulation of helicase activity", "Positive regulation of hematopoietic progenitor cell differentiation", "Positive regulation of hematopoietic stem cell proliferation", "Positive regulation of hemopoiesis", "Positive regulation of hepatocyte proliferation", "Positive regulation of heterotypic cell cell adhesion", "Positive regulation of hexokinase activity", "Positive regulation of hippo signaling", "Positive regulation of histone acetylation", "Positive regulation of histone deacetylation", "Positive regulation of histone h3 k27 methylation", "Positive regulation of histone h3 k4 methylation", "Positive regulation of histone h3 k9 acetylation", "Positive regulation of histone h3 k9 methylation", "Positive regulation of histone h4 acetylation", "Positive regulation of histone methylation", "Positive regulation of histone modification", "Positive regulation of histone phosphorylation", "Positive regulation of histone ubiquitination", "Positive regulation of homotypic cell cell adhesion", "Positive regulation of hormone biosynthetic process", "Positive regulation of hormone metabolic process", "Positive regulation of hormone secretion", "Positive regulation of humoral immune response", "Positive regulation of hydrogen peroxide mediated programmed cell death", "Positive regulation of hydrogen peroxide metabolic process", "Positive regulation of hydrolase activity", "Positive regulation of i kappab kinase nf kappab signaling", "Positive regulation of i kappab phosphorylation", "Positive regulation of immune effector process", "Positive regulation of immune response", "Positive regulation of immune system process", "Positive regulation of immunoglobulin production", "Positive regulation of inclusion body assembly", "Positive regulation of inflammatory response", "Positive regulation of inflammatory response to antigenic stimulus", "Positive regulation of inhibitory postsynaptic potential", "Positive regulation of innate immune response", "Positive regulation of insulin like growth factor receptor signaling pathway", "Positive regulation of insulin secretion", "Positive regulation of insulin secretion involved in cellular response to glucose stimulus", "Positive regulation of integrin activation", "Positive regulation of integrin mediated signaling pathway", "Positive regulation of interferon alpha production", "Positive regulation of interferon beta production", "Positive regulation of interferon gamma production", "Positive regulation of interleukin 1 alpha production", "Positive regulation of interleukin 1 beta production", "Positive regulation of interleukin 1 production", "Positive regulation of interleukin 10 production", "Positive regulation of interleukin 12 production", "Positive regulation of interleukin 17 production", "Positive regulation of interleukin 18 production", "Positive regulation of interleukin 2 production", "Positive regulation of interleukin 6 production", "Positive regulation of interleukin 8 production", "Positive regulation of intracellular lipid transport", "Positive regulation of intracellular protein transport", "Positive regulation of intracellular signal transduction", "Positive regulation of intracellular steroid hormone receptor signaling pathway", "Positive regulation of intracellular transport", "Positive regulation of intrinsic apoptotic signaling pathway", "Positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Positive regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Positive regulation of ion transmembrane transport", "Positive regulation of ion transport", "Positive regulation of ire1 mediated unfolded protein response", "Positive regulation of isotype switching", "Positive regulation of isotype switching to iga isotypes", "Positive regulation of isotype switching to igg isotypes", "Positive regulation of jnk cascade", "Positive regulation of jun kinase activity", "Positive regulation of keratinocyte differentiation", "Positive regulation of keratinocyte proliferation", "Positive regulation of kinase activity", "Positive regulation of lamellipodium assembly", "Positive regulation of lamellipodium morphogenesis", "Positive regulation of lamellipodium organization", "Positive regulation of leukocyte adhesion to vascular endothelial cell", "Positive regulation of leukocyte apoptotic process", "Positive regulation of leukocyte cell cell adhesion", "Positive regulation of leukocyte chemotaxis", "Positive regulation of leukocyte degranulation", "Positive regulation of leukocyte mediated immunity", "Positive regulation of leukocyte migration", "Positive regulation of leukocyte proliferation", "Positive regulation of ligase activity", "Positive regulation of lipase activity", "Positive regulation of lipid biosynthetic process", "Positive regulation of lipid catabolic process", "Positive regulation of lipid kinase activity", "Positive regulation of lipid localization", "Positive regulation of lipid metabolic process", "Positive regulation of lipid storage", "Positive regulation of lipid transport", "Positive regulation of lipopolysaccharide mediated signaling pathway", "Positive regulation of lipoprotein particle clearance", "Positive regulation of locomotion", "Positive regulation of long term synaptic depression", "Positive regulation of long term synaptic potentiation", "Positive regulation of low density lipoprotein receptor activity", "Positive regulation of lyase activity", "Positive regulation of lymphocyte anergy", "Positive regulation of lymphocyte apoptotic process", "Positive regulation of lymphocyte chemotaxis", "Positive regulation of lymphocyte differentiation", "Positive regulation of lymphocyte mediated immunity", "Positive regulation of lymphocyte migration", "Positive regulation of macroautophagy", "Positive regulation of macrophage activation", "Positive regulation of macrophage chemotaxis", "Positive regulation of macrophage cytokine production", "Positive regulation of macrophage migration", "Positive regulation of maintenance of sister chromatid cohesion", "Positive regulation of mammary gland epithelial cell proliferation", "Positive regulation of map kinase activity", "Positive regulation of mapk cascade", "Positive regulation of mast cell activation", "Positive regulation of mast cell activation involved in immune response", "Positive regulation of megakaryocyte differentiation", "Positive regulation of meiotic cell cycle", "Positive regulation of meiotic nuclear division", "Positive regulation of membrane depolarization", "Positive regulation of membrane permeability", "Positive regulation of membrane potential", "Positive regulation of membrane protein ectodomain proteolysis", "Positive regulation of mesenchymal cell proliferation", "Positive regulation of mesenchymal stem cell proliferation", "Positive regulation of metallopeptidase activity", "Positive regulation of metaphase anaphase transition of cell cycle", "Positive regulation of mhc class i biosynthetic process", "Positive regulation of mhc class ii biosynthetic process", "Positive regulation of microglial cell activation", "Positive regulation of microtubule binding", "Positive regulation of microtubule nucleation", "Positive regulation of microtubule polymerization or depolymerization", "Positive regulation of mirna catabolic process", "Positive regulation of mirna mediated gene silencing by inhibition of translation", "Positive regulation of mirna metabolic process", "Positive regulation of mirna transcription", "Positive regulation of mitochondrial calcium ion concentration", "Positive regulation of mitochondrial depolarization", "Positive regulation of mitochondrial fission", "Positive regulation of mitochondrial membrane potential", "Positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Positive regulation of mitochondrial translation", "Positive regulation of mitochondrion organization", "Positive regulation of mitophagy", "Positive regulation of mitophagy in response to mitochondrial depolarization", "Positive regulation of mitotic cell cycle", "Positive regulation of mitotic cell cycle phase transition", "Positive regulation of mitotic cell cycle spindle assembly checkpoint", "Positive regulation of mitotic nuclear division", "Positive regulation of molecular function", "Positive regulation of monocyte chemotaxis", "Positive regulation of monocyte differentiation", "Positive regulation of mononuclear cell migration", "Positive regulation of monooxygenase activity", "Positive regulation of morphogenesis of an epithelium", "Positive regulation of mrna 3 end processing", "Positive regulation of mrna metabolic process", "Positive regulation of mrna processing", "Positive regulation of mrna splicing via spliceosome", "Positive regulation of multicellular organism growth", "Positive regulation of multicellular organismal process", "Positive regulation of muscle adaptation", "Positive regulation of muscle cell apoptotic process", "Positive regulation of muscle cell differentiation", "Positive regulation of muscle contraction", "Positive regulation of muscle hypertrophy", "Positive regulation of muscle tissue development", "Positive regulation of myelination", "Positive regulation of myeloid cell apoptotic process", "Positive regulation of myeloid cell differentiation", "Positive regulation of myeloid leukocyte cytokine production involved in immune response", "Positive regulation of myeloid leukocyte differentiation", "Positive regulation of myeloid leukocyte mediated immunity", "Positive regulation of myoblast differentiation", "Positive regulation of myoblast fusion", "Positive regulation of myoblast proliferation", "Positive regulation of myotube differentiation", "Positive regulation of nad p h oxidase activity", "Positive regulation of natural killer cell activation", "Positive regulation of natural killer cell mediated cytotoxicity", "Positive regulation of natural killer cell mediated immune response to tumor cell", "Positive regulation of natural killer cell mediated immunity", "Positive regulation of necrotic cell death", "Positive regulation of nervous system development", "Positive regulation of nervous system process", "Positive regulation of neural precursor cell proliferation", "Positive regulation of neuroblast proliferation", "Positive regulation of neurogenesis", "Positive regulation of neuroinflammatory response", "Positive regulation of neuron apoptotic process", "Positive regulation of neuron death", "Positive regulation of neuron differentiation", "Positive regulation of neuron migration", "Positive regulation of neuron projection arborization", "Positive regulation of neuron projection development", "Positive regulation of neuron projection regeneration", "Positive regulation of neurotransmitter secretion", "Positive regulation of neurotransmitter transport", "Positive regulation of neurotransmitter uptake", "Positive regulation of neurotrophin trk receptor signaling pathway", "Positive regulation of neutrophil migration", "Positive regulation of nf kappab transcription factor activity", "Positive regulation of nik nf kappab signaling", "Positive regulation of nitric oxide mediated signal transduction", "Positive regulation of nitric oxide metabolic process", "Positive regulation of nitric oxide synthase activity", "Positive regulation of nitric oxide synthase biosynthetic process", "Positive regulation of nk t cell activation", "Positive regulation of nlrp3 inflammasome complex assembly", "Positive regulation of non motile cilium assembly", "Positive regulation of nuclear cell cycle dna replication", "Positive regulation of nuclear division", "Positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Positive regulation of nuclease activity", "Positive regulation of nucleobase containing compound metabolic process", "Positive regulation of nucleobase containing compound transport", "Positive regulation of nucleocytoplasmic transport", "Positive regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Positive regulation of nucleotide binding oligomerization domain containing signaling pathway", "Positive regulation of nucleotide biosynthetic process", "Positive regulation of nucleotide metabolic process", "Positive regulation of oligodendrocyte differentiation", "Positive regulation of opsonization", "Positive regulation of organ growth", "Positive regulation of organelle assembly", "Positive regulation of organelle organization", "Positive regulation of organic acid transport", "Positive regulation of ossification", "Positive regulation of osteoblast differentiation", "Positive regulation of osteoblast proliferation", "Positive regulation of osteoclast differentiation", "Positive regulation of oxidative stress induced cell death", "Positive regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Positive regulation of oxidative stress induced neuron death", "Positive regulation of oxidoreductase activity", "Positive regulation of p38mapk cascade", "Positive regulation of pathway restricted smad protein phosphorylation", "Positive regulation of pattern recognition receptor signaling pathway", "Positive regulation of peptidase activity", "Positive regulation of peptide secretion", "Positive regulation of peptidyl lysine acetylation", "Positive regulation of peptidyl serine phosphorylation", "Positive regulation of peptidyl threonine phosphorylation", "Positive regulation of peptidyl tyrosine phosphorylation", "Positive regulation of peroxisome proliferator activated receptor signaling pathway", "Positive regulation of phagocytosis", "Positive regulation of phosphatase activity", "Positive regulation of phosphatidylinositol 3 kinase signaling", "Positive regulation of phospholipase a2 activity", "Positive regulation of phospholipase activity", "Positive regulation of phospholipid biosynthetic process", "Positive regulation of phospholipid metabolic process", "Positive regulation of phospholipid translocation", "Positive regulation of phosphoprotein phosphatase activity", "Positive regulation of phosphorus metabolic process", "Positive regulation of pinocytosis", "Positive regulation of plasma membrane bounded cell projection assembly", "Positive regulation of plasminogen activation", "Positive regulation of platelet aggregation", "Positive regulation of podosome assembly", "Positive regulation of posttranscriptional gene silencing", "Positive regulation of potassium ion import across plasma membrane", "Positive regulation of potassium ion transmembrane transporter activity", "Positive regulation of potassium ion transport", "Positive regulation of production of mirnas involved in gene silencing by mirna", "Positive regulation of production of molecular mediator of immune response", "Positive regulation of programmed necrotic cell death", "Positive regulation of prostaglandin biosynthetic process", "Positive regulation of proteasomal ubiquitin dependent protein catabolic process", "Positive regulation of protein acetylation", "Positive regulation of protein autophosphorylation", "Positive regulation of protein binding", "Positive regulation of protein catabolic process", "Positive regulation of protein catabolic process in the vacuole", "Positive regulation of protein containing complex assembly", "Positive regulation of protein containing complex disassembly", "Positive regulation of protein deacetylation", "Positive regulation of protein dephosphorylation", "Positive regulation of protein depolymerization", "Positive regulation of protein deubiquitination", "Positive regulation of protein exit from endoplasmic reticulum", "Positive regulation of protein export from nucleus", "Positive regulation of protein glycosylation", "Positive regulation of protein import", "Positive regulation of protein k63 linked ubiquitination", "Positive regulation of protein kinase a signaling", "Positive regulation of protein kinase activity", "Positive regulation of protein kinase b signaling", "Positive regulation of protein localization", "Positive regulation of protein localization to cell cortex", "Positive regulation of protein localization to cell periphery", "Positive regulation of protein localization to cell surface", "Positive regulation of protein localization to centrosome", "Positive regulation of protein localization to cilium", "Positive regulation of protein localization to early endosome", "Positive regulation of protein localization to membrane", "Positive regulation of protein localization to nucleus", "Positive regulation of protein localization to synapse", "Positive regulation of protein maturation", "Positive regulation of protein metabolic process", "Positive regulation of protein modification by small protein conjugation or removal", "Positive regulation of protein modification process", "Positive regulation of protein monoubiquitination", "Positive regulation of protein neddylation", "Positive regulation of protein phosphorylation", "Positive regulation of protein polymerization", "Positive regulation of protein polyubiquitination", "Positive regulation of protein secretion", "Positive regulation of protein serine threonine kinase activity", "Positive regulation of protein sumoylation", "Positive regulation of protein targeting to membrane", "Positive regulation of protein tyrosine kinase activity", "Positive regulation of proteolysis", "Positive regulation of proteolysis involved in cellular protein catabolic process", "Positive regulation of pseudopodium assembly", "Positive regulation of reactive oxygen species biosynthetic process", "Positive regulation of reactive oxygen species metabolic process", "Positive regulation of receptor binding", "Positive regulation of receptor catabolic process", "Positive regulation of receptor clustering", "Positive regulation of receptor internalization", "Positive regulation of receptor mediated endocytosis", "Positive regulation of receptor recycling", "Positive regulation of receptor signaling pathway via stat", "Positive regulation of regulated secretory pathway", "Positive regulation of release of cytochrome c from mitochondria", "Positive regulation of release of sequestered calcium ion into cytosol", "Positive regulation of renal sodium excretion", "Positive regulation of reproductive process", "Positive regulation of respiratory burst", "Positive regulation of response to biotic stimulus", "Positive regulation of response to cytokine stimulus", "Positive regulation of response to dna damage stimulus", "Positive regulation of response to endoplasmic reticulum stress", "Positive regulation of response to external stimulus", "Positive regulation of response to interferon gamma", "Positive regulation of response to oxidative stress", "Positive regulation of response to reactive oxygen species", "Positive regulation of response to tumor cell", "Positive regulation of response to wounding", "Positive regulation of retinoic acid receptor signaling pathway", "Positive regulation of rho protein signal transduction", "Positive regulation of rig i signaling pathway", "Positive regulation of rna binding", "Positive regulation of rna export from nucleus", "Positive regulation of rna metabolic process", "Positive regulation of rna polymerase ii transcription preinitiation complex assembly", "Positive regulation of rna splicing", "Positive regulation of rrna processing", "Positive regulation of ruffle assembly", "Positive regulation of ryanodine sensitive calcium release channel activity", "Positive regulation of secretion", "Positive regulation of sequestering of calcium ion", "Positive regulation of sequestering of triglyceride", "Positive regulation of signal transduction by p53 class mediator", "Positive regulation of signaling", "Positive regulation of signaling receptor activity", "Positive regulation of sister chromatid cohesion", "Positive regulation of skeletal muscle fiber development", "Positive regulation of skeletal muscle tissue development", "Positive regulation of skeletal muscle tissue growth", "Positive regulation of smad protein signal transduction", "Positive regulation of small gtpase mediated signal transduction", "Positive regulation of small molecule metabolic process", "Positive regulation of smooth muscle cell apoptotic process", "Positive regulation of smooth muscle cell differentiation", "Positive regulation of smooth muscle cell migration", "Positive regulation of smooth muscle cell proliferation", "Positive regulation of smooth muscle contraction", "Positive regulation of smoothened signaling pathway", "Positive regulation of sodium ion transmembrane transport", "Positive regulation of sodium ion transmembrane transporter activity", "Positive regulation of sodium ion transport", "Positive regulation of sphingolipid biosynthetic process", "Positive regulation of spindle assembly", "Positive regulation of sprouting angiogenesis", "Positive regulation of stem cell differentiation", "Positive regulation of stem cell proliferation", "Positive regulation of steroid biosynthetic process", "Positive regulation of steroid hormone biosynthetic process", "Positive regulation of steroid metabolic process", "Positive regulation of sterol transport", "Positive regulation of stress activated protein kinase signaling cascade", "Positive regulation of stress fiber assembly", "Positive regulation of striated muscle cell apoptotic process", "Positive regulation of striated muscle cell differentiation", "Positive regulation of striated muscle contraction", "Positive regulation of substrate adhesion dependent cell spreading", "Positive regulation of supramolecular fiber organization", "Positive regulation of synapse assembly", "Positive regulation of synapse maturation", "Positive regulation of synaptic plasticity", "Positive regulation of synaptic transmission", "Positive regulation of synaptic transmission gabaergic", "Positive regulation of synaptic transmission glutamatergic", "Positive regulation of synaptic vesicle endocytosis", "Positive regulation of synaptic vesicle exocytosis", "Positive regulation of synaptic vesicle recycling", "Positive regulation of syncytium formation by plasma membrane fusion", "Positive regulation of systemic arterial blood pressure", "Positive regulation of t cell apoptotic process", "Positive regulation of t cell cytokine production", "Positive regulation of t cell differentiation in thymus", "Positive regulation of t cell mediated cytotoxicity", "Positive regulation of t cell mediated immune response to tumor cell", "Positive regulation of t cell mediated immunity", "Positive regulation of t cell migration", "Positive regulation of t cell proliferation", "Positive regulation of t cell receptor signaling pathway", "Positive regulation of t cell tolerance induction", "Positive regulation of t helper 1 cell differentiation", "Positive regulation of t helper cell differentiation", "Positive regulation of tau protein kinase activity", "Positive regulation of telomerase activity", "Positive regulation of telomerase rna localization to cajal body", "Positive regulation of telomere capping", "Positive regulation of telomere maintenance", "Positive regulation of telomere maintenance via telomere lengthening", "Positive regulation of tissue remodeling", "Positive regulation of tolerance induction", "Positive regulation of toll like receptor 3 signaling pathway", "Positive regulation of toll like receptor 9 signaling pathway", "Positive regulation of toll like receptor signaling pathway", "Positive regulation of tor signaling", "Positive regulation of torc1 signaling", "Positive regulation of transcription by rna polymerase i", "Positive regulation of transcription by rna polymerase ii", "Positive regulation of transcription by rna polymerase iii", "Positive regulation of transcription elongation from rna polymerase ii promoter", "Positive regulation of transcription from rna polymerase ii promoter in response to endoplasmic reticulum stress", "Positive regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Positive regulation of transcription from rna polymerase ii promoter in response to stress", "Positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus", "Positive regulation of transcription of notch receptor target", "Positive regulation of transcription of nucleolar large rrna by rna polymerase i", "Positive regulation of transcription regulatory region dna binding", "Positive regulation of transferase activity", "Positive regulation of translation", "Positive regulation of translation in response to endoplasmic reticulum stress", "Positive regulation of translation in response to stress", "Positive regulation of translational initiation", "Positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Positive regulation of transmembrane transport", "Positive regulation of transmission of nerve impulse", "Positive regulation of transport", "Positive regulation of transporter activity", "Positive regulation of triglyceride biosynthetic process", "Positive regulation of triglyceride catabolic process", "Positive regulation of triglyceride metabolic process", "Positive regulation of trophoblast cell migration", "Positive regulation of tumor necrosis factor mediated signaling pathway", "Positive regulation of tumor necrosis factor superfamily cytokine production", "Positive regulation of type i interferon mediated signaling pathway", "Positive regulation of type i interferon production", "Positive regulation of tyrosine phosphorylation of stat protein", "Positive regulation of ubiquitin dependent protein catabolic process", "Positive regulation of ubiquitin protein ligase activity", "Positive regulation of ubiquitin protein transferase activity", "Positive regulation of unsaturated fatty acid biosynthetic process", "Positive regulation of urine volume", "Positive regulation of uterine smooth muscle contraction", "Positive regulation of vacuole organization", "Positive regulation of vascular associated smooth muscle cell apoptotic process", "Positive regulation of vascular associated smooth muscle cell differentiation", "Positive regulation of vascular associated smooth muscle cell migration", "Positive regulation of vascular associated smooth muscle cell proliferation", "Positive regulation of vascular endothelial cell proliferation", "Positive regulation of vascular endothelial growth factor production", "Positive regulation of vascular endothelial growth factor signaling pathway", "Positive regulation of vascular permeability", "Positive regulation of vasculature development", "Positive regulation of vasculogenesis", "Positive regulation of vasoconstriction", "Positive regulation of vesicle fusion", "Positive regulation of viral genome replication", "Positive regulation of viral life cycle", "Positive regulation of viral process", "Positive regulation of vitamin d receptor signaling pathway", "Positive regulation of voltage gated calcium channel activity", "Positive regulation of wnt signaling pathway", "Positive regulation of wound healing", "Positive regulation of wound healing spreading of epidermal cells", "Positive t cell selection", "Post anal tail morphogenesis", "Post chaperonin tubulin folding pathway", "Post embryonic animal morphogenesis", "Post embryonic animal organ development", "Post embryonic animal organ morphogenesis", "Post embryonic camera type eye development", "Post embryonic development", "Post embryonic eye morphogenesis", "Post golgi vesicle mediated transport", "Post translational protein modification", "Postreplication repair", "Postsynapse assembly", "Postsynapse organization", "Postsynapse to nucleus signaling pathway", "Postsynaptic actin cytoskeleton organization", "Postsynaptic cytoskeleton organization", "Postsynaptic density protein 95 clustering", "Postsynaptic membrane assembly", "Postsynaptic membrane organization", "Postsynaptic modulation of chemical synaptic transmission", "Postsynaptic neurotransmitter receptor internalization", "Postsynaptic signal transduction", "Postsynaptic specialization organization", "Posttranscriptional regulation of gene expression", "Posttranslational protein targeting to endoplasmic reticulum membrane", "Posttranslational protein targeting to membrane translocation", "Potassium ion export across plasma membrane", "Potassium ion homeostasis", "Potassium ion import across plasma membrane", "Potassium ion transport", "Pre mirna processing", "Preassembly of gpi anchor in er membrane", "Prenylation", "Prepulse inhibition", "Presynapse organization", "Presynaptic active zone organization", "Presynaptic endocytosis", "Presynaptic modulation of chemical synaptic transmission", "Prevention of polyspermy", "Primary alcohol biosynthetic process", "Primary alcohol catabolic process", "Primary alcohol metabolic process", "Primary amino compound biosynthetic process", "Primary amino compound metabolic process", "Primary mirna processing", "Primitive hemopoiesis", "Pro b cell differentiation", "Process utilizing autophagic mechanism", "Production of molecular mediator involved in inflammatory response", "Production of molecular mediator of immune response", "Production of sirna involved in rna interference", "Progesterone biosynthetic process", "Progesterone metabolic process", "Progesterone receptor signaling pathway", "Programmed cell death", "Programmed cell death in response to reactive oxygen species", "Programmed cell death involved in cell development", "Programmed necrotic cell death", "Prolactin secretion", "Proline metabolic process", "Proline transport", "Pronephros development", "Proprioception", "Prostaglandin transport", "Prostanoid biosynthetic process", "Prostanoid metabolic process", "Prostate gland development", "Prostate gland growth", "Prostate gland morphogenesis", "Prostate glandular acinus development", "Prostate glandular acinus morphogenesis", "Prosthetic group metabolic process", "Proteasomal protein catabolic process", "Proteasome assembly", "Proteasome mediated ubiquitin dependent protein catabolic process", "Protection from natural killer cell mediated cytotoxicity", "Protection from non homologous end joining at telomere", "Protein acetylation", "Protein activation cascade", "Protein acylation", "Protein adp ribosylation", "Protein auto adp ribosylation", "Protein autophosphorylation", "Protein autoprocessing", "Protein autoubiquitination", "Protein catabolic process", "Protein catabolic process in the vacuole", "Protein complex oligomerization", "Protein containing complex disassembly", "Protein containing complex localization", "Protein containing complex organization", "Protein containing complex remodeling", "Protein de adp ribosylation", "Protein deglycosylation", "Protein demannosylation", "Protein demethylation", "Protein deneddylation", "Protein depalmitoylation", "Protein dephosphorylation", "Protein depolymerization", "Protein destabilization", "Protein desumoylation", "Protein deubiquitination involved in ubiquitin dependent protein catabolic process", "Protein dna complex assembly", "Protein dna complex disassembly", "Protein dna complex subunit organization", "Protein dna covalent cross linking repair", "Protein exit from endoplasmic reticulum", "Protein export from nucleus", "Protein folding", "Protein folding in endoplasmic reticulum", "Protein geranylgeranylation", "Protein heterooligomerization", "Protein heterotetramerization", "Protein hexamerization", "Protein homooligomerization", "Protein homotetramerization", "Protein hydroxylation", "Protein import", "Protein import into mitochondrial matrix", "Protein import into peroxisome matrix", "Protein import into peroxisome membrane", "Protein insertion into er membrane", "Protein insertion into er membrane by stop transfer membrane anchor sequence", "Protein insertion into membrane", "Protein insertion into mitochondrial inner membrane", "Protein insertion into mitochondrial membrane involved in apoptotic signaling pathway", "Protein k11 linked deubiquitination", "Protein k11 linked ubiquitination", "Protein k27 linked ubiquitination", "Protein k29 linked ubiquitination", "Protein k48 linked deubiquitination", "Protein k48 linked ubiquitination", "Protein k6 linked ubiquitination", "Protein k63 linked deubiquitination", "Protein k63 linked ubiquitination", "Protein kinase a signaling", "Protein kinase b signaling", "Protein kinase c signaling", "Protein lipid complex assembly", "Protein lipid complex subunit organization", "Protein localization to adherens junction", "Protein localization to axon", "Protein localization to basolateral plasma membrane", "Protein localization to cell cell junction", "Protein localization to cell cortex", "Protein localization to cell junction", "Protein localization to cell periphery", "Protein localization to cell surface", "Protein localization to chromatin", "Protein localization to chromosome", "Protein localization to chromosome centromeric region", "Protein localization to chromosome telomeric region", "Protein localization to ciliary membrane", "Protein localization to cilium", "Protein localization to condensed chromosome", "Protein localization to cytoplasmic stress granule", "Protein localization to cytoskeleton", "Protein localization to early endosome", "Protein localization to endoplasmic reticulum", "Protein localization to endoplasmic reticulum exit site", "Protein localization to endosome", "Protein localization to extracellular region", "Protein localization to golgi apparatus", "Protein localization to lysosome", "Protein localization to membrane raft", "Protein localization to microtubule", "Protein localization to microtubule end", "Protein localization to microtubule organizing center", "Protein localization to mitochondrion", "Protein localization to non motile cilium", "Protein localization to nuclear body", "Protein localization to nuclear envelope", "Protein localization to nucleolus", "Protein localization to nucleoplasm", "Protein localization to nucleus", "Protein localization to organelle", "Protein localization to perinuclear region of cytoplasm", "Protein localization to phagophore assembly site", "Protein localization to plasma membrane", "Protein localization to postsynapse", "Protein localization to presynapse", "Protein localization to synapse", "Protein localization to vacuole", "Protein mannosylation", "Protein maturation", "Protein maturation by 4fe 4s cluster transfer", "Protein maturation by iron sulfur cluster transfer", "Protein maturation by protein folding", "Protein methylation", "Protein modification by small protein conjugation", "Protein modification by small protein conjugation or removal", "Protein modification by small protein removal", "Protein monoubiquitination", "Protein n linked glycosylation", "Protein neddylation", "Protein nitrosylation", "Protein o linked fucosylation", "Protein o linked glycosylation", "Protein o linked glycosylation via serine", "Protein o linked glycosylation via threonine", "Protein o linked mannosylation", "Protein oxidation", "Protein peptidyl prolyl isomerization", "Protein poly adp ribosylation", "Protein polyglutamylation", "Protein polymerization", "Protein polyubiquitination", "Protein polyufmylation", "Protein processing", "Protein processing involved in protein targeting to mitochondrion", "Protein quality control for misfolded or incompletely synthesized proteins", "Protein refolding", "Protein repair", "Protein retention in er lumen", "Protein retention in golgi apparatus", "Protein stabilization", "Protein sumoylation", "Protein targeting", "Protein targeting to lysosome", "Protein targeting to membrane", "Protein targeting to mitochondrion", "Protein targeting to peroxisome", "Protein targeting to vacuole", "Protein tetramerization", "Protein transmembrane import into intracellular organelle", "Protein transmembrane transport", "Protein transport along microtubule", "Protein transport to vacuole involved in ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Protein transport within lipid bilayer", "Protein trimerization", "Protein ufmylation", "Proteoglycan biosynthetic process", "Proteoglycan metabolic process", "Proteolysis", "Proton transmembrane transport", "Proton transporting two sector atpase complex assembly", "Proton transporting v type atpase complex assembly", "Protoporphyrinogen ix biosynthetic process", "Protoporphyrinogen ix metabolic process", "Proximal distal pattern formation", "Proximal distal pattern formation involved in nephron development", "Proximal tubule development", "Pseudopodium organization", "Pseudouridine synthesis", "Pteridine containing compound biosynthetic process", "Pteridine containing compound metabolic process", "Pulmonary artery morphogenesis", "Pulmonary valve development", "Pulmonary valve morphogenesis", "Purine containing compound biosynthetic process", "Purine containing compound catabolic process", "Purine containing compound metabolic process", "Purine containing compound salvage", "Purine containing compound transmembrane transport", "Purine deoxyribonucleoside metabolic process", "Purine deoxyribonucleoside monophosphate catabolic process", "Purine deoxyribonucleoside monophosphate metabolic process", "Purine deoxyribonucleoside triphosphate metabolic process", "Purine deoxyribonucleotide biosynthetic process", "Purine deoxyribonucleotide catabolic process", "Purine deoxyribonucleotide metabolic process", "Purine nucleobase biosynthetic process", "Purine nucleobase metabolic process", "Purine nucleoside biosynthetic process", "Purine nucleoside catabolic process", "Purine nucleoside diphosphate biosynthetic process", "Purine nucleoside metabolic process", "Purine nucleoside monophosphate biosynthetic process", "Purine nucleoside monophosphate catabolic process", "Purine nucleoside monophosphate metabolic process", "Purine nucleoside triphosphate catabolic process", "Purine nucleotide catabolic process", "Purine nucleotide salvage", "Purine nucleotide transport", "Purine ribonucleoside catabolic process", "Purine ribonucleoside metabolic process", "Purine ribonucleoside salvage", "Purine ribonucleotide salvage", "Purinergic nucleotide receptor signaling pathway", "Putrescine biosynthetic process", "Putrescine metabolic process", "Pyramidal neuron development", "Pyramidal neuron differentiation", "Pyridine containing compound biosynthetic process", "Pyridine containing compound catabolic process", "Pyridine containing compound metabolic process", "Pyridine nucleotide biosynthetic process", "Pyridine nucleotide metabolic process", "Pyrimidine containing compound biosynthetic process", "Pyrimidine containing compound catabolic process", "Pyrimidine containing compound metabolic process", "Pyrimidine containing compound salvage", "Pyrimidine containing compound transmembrane transport", "Pyrimidine deoxyribonucleoside metabolic process", "Pyrimidine deoxyribonucleoside monophosphate biosynthetic process", "Pyrimidine deoxyribonucleoside monophosphate metabolic process", "Pyrimidine deoxyribonucleoside triphosphate metabolic process", "Pyrimidine deoxyribonucleotide biosynthetic process", "Pyrimidine deoxyribonucleotide metabolic process", "Pyrimidine dimer repair", "Pyrimidine nucleobase biosynthetic process", "Pyrimidine nucleobase catabolic process", "Pyrimidine nucleobase metabolic process", "Pyrimidine nucleoside catabolic process", "Pyrimidine nucleoside diphosphate biosynthetic process", "Pyrimidine nucleoside diphosphate metabolic process", "Pyrimidine nucleoside metabolic process", "Pyrimidine nucleoside monophosphate biosynthetic process", "Pyrimidine nucleoside monophosphate metabolic process", "Pyrimidine nucleoside transport", "Pyrimidine nucleoside triphosphate biosynthetic process", "Pyrimidine nucleoside triphosphate metabolic process", "Pyrimidine nucleotide catabolic process", "Pyrimidine nucleotide metabolic process", "Pyrimidine ribonucleoside diphosphate metabolic process", "Pyrimidine ribonucleoside monophosphate metabolic process", "Pyrimidine ribonucleoside triphosphate biosynthetic process", "Pyrimidine ribonucleoside triphosphate metabolic process", "Pyrimidine ribonucleotide biosynthetic process", "Pyrimidine ribonucleotide metabolic process", "Pyroptosis", "Pyruvate metabolic process", "Pyruvate transmembrane transport", "Pyruvate transport", "Quaternary ammonium group transport", "Quinone metabolic process", "R loop disassembly", "Rab protein signal transduction", "Rac protein signal transduction", "Radial glial cell differentiation", "Rap protein signal transduction", "Ras protein signal transduction", "Reactive nitrogen species metabolic process", "Reactive oxygen species biosynthetic process", "Reactive oxygen species metabolic process", "Receptor catabolic process", "Receptor clustering", "Receptor diffusion trapping", "Receptor internalization", "Receptor localization to synapse", "Receptor mediated endocytosis", "Receptor mediated endocytosis involved in cholesterol transport", "Receptor metabolic process", "Receptor recycling", "Receptor signaling pathway via stat", "Receptor transactivation", "Recognition of apoptotic cell", "Recombinational repair", "Reelin mediated signaling pathway", "Reflex", "Regeneration", "Regionalization", "Regulated exocytosis", "Regulation by virus of viral protein levels in host cell", "Regulation of 3 utr mediated mrna stabilization", "Regulation of actin cytoskeleton reorganization", "Regulation of actin filament based movement", "Regulation of actin filament based process", "Regulation of actin filament bundle assembly", "Regulation of actin filament length", "Regulation of actin filament organization", "Regulation of actin nucleation", "Regulation of action potential", "Regulation of activin receptor signaling pathway", "Regulation of actomyosin structure organization", "Regulation of acute inflammatory response", "Regulation of acute inflammatory response to antigenic stimulus", "Regulation of acyl coa biosynthetic process", "Regulation of adaptive immune response", "Regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Regulation of adenylate cyclase activity", "Regulation of adherens junction organization", "Regulation of adipose tissue development", "Regulation of aerobic respiration", "Regulation of alcohol biosynthetic process", "Regulation of alpha beta t cell activation", "Regulation of alpha beta t cell differentiation", "Regulation of alternative mrna splicing via spliceosome", "Regulation of amino acid transmembrane transport", "Regulation of amino acid transport", "Regulation of amyloid beta clearance", "Regulation of amyloid fibril formation", "Regulation of amyloid precursor protein catabolic process", "Regulation of anaphase promoting complex dependent catabolic process", "Regulation of anatomical structure morphogenesis", "Regulation of anatomical structure size", "Regulation of androgen receptor signaling pathway", "Regulation of animal organ formation", "Regulation of animal organ morphogenesis", "Regulation of anion channel activity", "Regulation of anion transmembrane transport", "Regulation of anion transport", "Regulation of anoikis", "Regulation of antifungal innate immune response", "Regulation of antigen receptor mediated signaling pathway", "Regulation of apoptotic cell clearance", "Regulation of apoptotic dna fragmentation", "Regulation of apoptotic process involved in development", "Regulation of apoptotic signaling pathway", "Regulation of appetite", "Regulation of arachidonic acid secretion", "Regulation of arp2 3 complex mediated actin nucleation", "Regulation of aspartic type endopeptidase activity involved in amyloid precursor protein catabolic process", "Regulation of aspartic type peptidase activity", "Regulation of astrocyte activation", "Regulation of astrocyte differentiation", "Regulation of atp biosynthetic process", "Regulation of atp dependent activity", "Regulation of atp metabolic process", "Regulation of atpase coupled calcium transmembrane transporter activity", "Regulation of atrial cardiac muscle cell membrane repolarization", "Regulation of attachment of spindle microtubules to kinetochore", "Regulation of autophagosome maturation", "Regulation of autophagy", "Regulation of autophagy of mitochondrion", "Regulation of autophagy of mitochondrion in response to mitochondrial depolarization", "Regulation of axon diameter", "Regulation of axon guidance", "Regulation of axonogenesis", "Regulation of b cell activation", "Regulation of b cell apoptotic process", "Regulation of b cell differentiation", "Regulation of b cell mediated immunity", "Regulation of b cell proliferation", "Regulation of b cell receptor signaling pathway", "Regulation of behavior", "Regulation of bicellular tight junction assembly", "Regulation of bile acid biosynthetic process", "Regulation of bile acid metabolic process", "Regulation of bile acid secretion", "Regulation of binding", "Regulation of biological process involved in symbiotic interaction", "Regulation of biomineralization", "Regulation of blood brain barrier permeability", "Regulation of blood circulation", "Regulation of blood pressure", "Regulation of bmp signaling pathway", "Regulation of body fluid levels", "Regulation of bone mineralization", "Regulation of bone remodeling", "Regulation of bone resorption", "Regulation of branching involved in lung morphogenesis", "Regulation of branching involved in prostate gland morphogenesis", "Regulation of branching involved in ureteric bud morphogenesis", "Regulation of branching morphogenesis of a nerve", "Regulation of brown fat cell differentiation", "Regulation of calcineurin mediated signaling", "Regulation of calcium ion dependent exocytosis", "Regulation of calcium ion export across plasma membrane", "Regulation of calcium ion import", "Regulation of calcium ion transmembrane transport", "Regulation of calcium ion transmembrane transporter activity", "Regulation of calcium ion transport", "Regulation of calcium ion transport into cytosol", "Regulation of calcium mediated signaling", "Regulation of camp dependent protein kinase activity", "Regulation of camp mediated signaling", "Regulation of canonical wnt signaling pathway", "Regulation of carbohydrate biosynthetic process", "Regulation of carbohydrate catabolic process", "Regulation of carbohydrate metabolic process", "Regulation of cardiac conduction", "Regulation of cardiac muscle adaptation", "Regulation of cardiac muscle cell action potential", "Regulation of cardiac muscle cell action potential involved in regulation of contraction", "Regulation of cardiac muscle cell membrane potential", "Regulation of cardiac muscle cell membrane repolarization", "Regulation of cardiac muscle cell proliferation", "Regulation of cardiac muscle contraction", "Regulation of cardiac muscle contraction by calcium ion signaling", "Regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion", "Regulation of cardiac muscle tissue development", "Regulation of cardioblast differentiation", "Regulation of cardiocyte differentiation", "Regulation of cartilage development", "Regulation of catabolic process", "Regulation of catecholamine metabolic process", "Regulation of cation channel activity", "Regulation of cation transmembrane transport", "Regulation of caveolin mediated endocytosis", "Regulation of cd4 positive alpha beta t cell activation", "Regulation of cd4 positive alpha beta t cell differentiation", "Regulation of cd40 signaling pathway", "Regulation of cd8 positive alpha beta t cell activation", "Regulation of cdc42 protein signal transduction", "Regulation of cell activation", "Regulation of cell adhesion", "Regulation of cell adhesion mediated by integrin", "Regulation of cell aging", "Regulation of cell cell adhesion", "Regulation of cell cell adhesion mediated by cadherin", "Regulation of cell cell adhesion mediated by integrin", "Regulation of cell communication by electrical coupling", "Regulation of cell communication by electrical coupling involved in cardiac conduction", "Regulation of cell cycle", "Regulation of cell cycle checkpoint", "Regulation of cell cycle g1 s phase transition", "Regulation of cell cycle g2 m phase transition", "Regulation of cell cycle phase transition", "Regulation of cell cycle process", "Regulation of cell death", "Regulation of cell development", "Regulation of cell differentiation", "Regulation of cell division", "Regulation of cell growth involved in cardiac muscle cell development", "Regulation of cell junction assembly", "Regulation of cell killing", "Regulation of cell matrix adhesion", "Regulation of cell maturation", "Regulation of cell migration involved in sprouting angiogenesis", "Regulation of cell morphogenesis", "Regulation of cell morphogenesis involved in differentiation", "Regulation of cell population proliferation", "Regulation of cell projection assembly", "Regulation of cell projection organization", "Regulation of cell projection size", "Regulation of cell shape", "Regulation of cell size", "Regulation of cell substrate adhesion", "Regulation of cell substrate junction organization", "Regulation of cellular amide metabolic process", "Regulation of cellular amine metabolic process", "Regulation of cellular amino acid metabolic process", "Regulation of cellular carbohydrate catabolic process", "Regulation of cellular carbohydrate metabolic process", "Regulation of cellular component biogenesis", "Regulation of cellular component movement", "Regulation of cellular component size", "Regulation of cellular extravasation", "Regulation of cellular ketone metabolic process", "Regulation of cellular localization", "Regulation of cellular macromolecule biosynthetic process", "Regulation of cellular ph", "Regulation of cellular ph reduction", "Regulation of cellular protein catabolic process", "Regulation of cellular respiration", "Regulation of cellular response to growth factor stimulus", "Regulation of cellular response to heat", "Regulation of cellular response to hypoxia", "Regulation of cellular response to insulin stimulus", "Regulation of cellular response to osmotic stress", "Regulation of cellular response to stress", "Regulation of cellular response to transforming growth factor beta stimulus", "Regulation of cellular response to vascular endothelial growth factor stimulus", "Regulation of centriole replication", "Regulation of centrosome cycle", "Regulation of chaperone mediated autophagy", "Regulation of chemokine mediated signaling pathway", "Regulation of chemotaxis", "Regulation of chloride transport", "Regulation of cholesterol biosynthetic process", "Regulation of cholesterol efflux", "Regulation of cholesterol esterification", "Regulation of cholesterol metabolic process", "Regulation of chondrocyte differentiation", "Regulation of chromatin assembly", "Regulation of chromatin assembly or disassembly", "Regulation of chromatin binding", "Regulation of chromatin organization", "Regulation of chromosome condensation", "Regulation of chromosome organization", "Regulation of chromosome segregation", "Regulation of chromosome separation", "Regulation of cilium assembly", "Regulation of cilium beat frequency", "Regulation of cilium beat frequency involved in ciliary motility", "Regulation of cilium dependent cell motility", "Regulation of cilium movement", "Regulation of circadian rhythm", "Regulation of clathrin dependent endocytosis", "Regulation of coagulation", "Regulation of collagen fibril organization", "Regulation of collagen metabolic process", "Regulation of collateral sprouting", "Regulation of complement activation", "Regulation of complement dependent cytotoxicity", "Regulation of connective tissue replacement", "Regulation of core promoter binding", "Regulation of corticotropin secretion", "Regulation of cyclase activity", "Regulation of cyclic nucleotide phosphodiesterase activity", "Regulation of cyclin dependent protein kinase activity", "Regulation of cysteine type endopeptidase activity", "Regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Regulation of cysteine type endopeptidase activity involved in execution phase of apoptosis", "Regulation of cytokinesis", "Regulation of cytoplasmic mrna processing body assembly", "Regulation of cytoplasmic translation", "Regulation of cytoplasmic translational elongation", "Regulation of cytoplasmic translational initiation", "Regulation of cytoplasmic transport", "Regulation of cytoskeleton organization", "Regulation of cytosolic calcium ion concentration", "Regulation of deacetylase activity", "Regulation of defense response", "Regulation of defense response to bacterium", "Regulation of defense response to fungus", "Regulation of defense response to virus", "Regulation of defense response to virus by host", "Regulation of delayed rectifier potassium channel activity", "Regulation of dendrite development", "Regulation of dendrite extension", "Regulation of dendrite morphogenesis", "Regulation of dendritic cell chemotaxis", "Regulation of dendritic cell differentiation", "Regulation of dendritic spine development", "Regulation of dendritic spine maintenance", "Regulation of dendritic spine morphogenesis", "Regulation of deoxyribonuclease activity", "Regulation of dephosphorylation", "Regulation of development heterochronic", "Regulation of developmental growth", "Regulation of digestive system process", "Regulation of dna binding", "Regulation of dna binding transcription factor activity", "Regulation of dna biosynthetic process", "Regulation of dna catabolic process", "Regulation of dna damage checkpoint", "Regulation of dna damage response signal transduction by p53 class mediator", "Regulation of dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator", "Regulation of dna demethylation", "Regulation of dna dependent dna replication", "Regulation of dna dependent dna replication initiation", "Regulation of dna directed dna polymerase activity", "Regulation of dna duplex unwinding", "Regulation of dna helicase activity", "Regulation of dna ligation", "Regulation of dna metabolic process", "Regulation of dna methylation", "Regulation of dna methylation dependent heterochromatin assembly", "Regulation of dna primase activity", "Regulation of dna recombination", "Regulation of dna repair", "Regulation of dna replication", "Regulation of dna strand elongation", "Regulation of dna templated transcription elongation", "Regulation of dna templated transcription in response to stress", "Regulation of dna templated transcription initiation", "Regulation of dna topoisomerase atp hydrolyzing activity", "Regulation of dopamine receptor signaling pathway", "Regulation of dopamine uptake involved in synaptic transmission", "Regulation of dopaminergic neuron differentiation", "Regulation of double strand break repair", "Regulation of double strand break repair via homologous recombination", "Regulation of double strand break repair via nonhomologous end joining", "Regulation of early endosome to late endosome transport", "Regulation of eating behavior", "Regulation of electron transfer activity", "Regulation of embryonic development", "Regulation of endocrine process", "Regulation of endocytic recycling", "Regulation of endocytosis", "Regulation of endodeoxyribonuclease activity", "Regulation of endodermal cell differentiation", "Regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Regulation of endoplasmic reticulum tubular network organization", "Regulation of endoplasmic reticulum unfolded protein response", "Regulation of endosome to plasma membrane protein transport", "Regulation of endothelial cell chemotaxis", "Regulation of endothelial cell development", "Regulation of endothelial cell differentiation", "Regulation of endothelial cell migration", "Regulation of entry of bacterium into host cell", "Regulation of epidermal growth factor activated receptor activity", "Regulation of epidermis development", "Regulation of epithelial cell apoptotic process", "Regulation of epithelial cell differentiation", "Regulation of epithelial cell differentiation involved in kidney development", "Regulation of epithelial cell migration", "Regulation of epithelial cell proliferation involved in lung morphogenesis", "Regulation of epithelial to mesenchymal transition", "Regulation of er associated ubiquitin dependent protein catabolic process", "Regulation of er to golgi vesicle mediated transport", "Regulation of erad pathway", "Regulation of erbb signaling pathway", "Regulation of erythrocyte differentiation", "Regulation of establishment of planar polarity", "Regulation of establishment of protein localization", "Regulation of establishment of protein localization to chromosome", "Regulation of establishment of protein localization to mitochondrion", "Regulation of establishment or maintenance of cell polarity", "Regulation of excretion", "Regulation of execution phase of apoptosis", "Regulation of exit from mitosis", "Regulation of exocytosis", "Regulation of exosomal secretion", "Regulation of extent of cell growth", "Regulation of extracellular matrix assembly", "Regulation of extracellular matrix disassembly", "Regulation of extracellular matrix organization", "Regulation of extrinsic apoptotic signaling pathway", "Regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Regulation of fat cell differentiation", "Regulation of fat cell proliferation", "Regulation of fatty acid beta oxidation", "Regulation of fatty acid biosynthetic process", "Regulation of fatty acid metabolic process", "Regulation of fatty acid oxidation", "Regulation of fatty acid transport", "Regulation of fc gamma receptor signaling pathway involved in phagocytosis", "Regulation of fc receptor mediated stimulatory signaling pathway", "Regulation of feeding behavior", "Regulation of fertilization", "Regulation of fibroblast growth factor receptor signaling pathway", "Regulation of fibroblast migration", "Regulation of filopodium assembly", "Regulation of focal adhesion disassembly", "Regulation of g protein coupled receptor signaling pathway", "Regulation of g0 to g1 transition", "Regulation of gamma aminobutyric acid secretion", "Regulation of gastrulation", "Regulation of gene expression by genomic imprinting", "Regulation of gene expression epigenetic", "Regulation of gene silencing by rna", "Regulation of generation of precursor metabolites and energy", "Regulation of genetic imprinting", "Regulation of germ cell proliferation", "Regulation of germinal center formation", "Regulation of glial cell apoptotic process", "Regulation of glial cell differentiation", "Regulation of glial cell migration", "Regulation of glial cell proliferation", "Regulation of gliogenesis", "Regulation of glucagon secretion", "Regulation of glucan biosynthetic process", "Regulation of glucocorticoid biosynthetic process", "Regulation of glucocorticoid metabolic process", "Regulation of glucocorticoid receptor signaling pathway", "Regulation of glucocorticoid secretion", "Regulation of gluconeogenesis", "Regulation of glucose import", "Regulation of glucose metabolic process", "Regulation of glucose transmembrane transport", "Regulation of glucosylceramidase activity", "Regulation of glutamate receptor clustering", "Regulation of glutamate secretion", "Regulation of glycogen catabolic process", "Regulation of glycogen metabolic process", "Regulation of glycogen starch synthase activity", "Regulation of glycolytic process", "Regulation of glycoprotein metabolic process", "Regulation of golgi organization", "Regulation of golgi to plasma membrane protein transport", "Regulation of gonad development", "Regulation of granulocyte chemotaxis", "Regulation of granulocyte differentiation", "Regulation of growth", "Regulation of gtp binding", "Regulation of gtpase activity", "Regulation of guanyl nucleotide exchange factor activity", "Regulation of hair cycle", "Regulation of hair follicle development", "Regulation of heart contraction", "Regulation of heart growth", "Regulation of heart rate", "Regulation of heart rate by cardiac conduction", "Regulation of heart rate by chemical signal", "Regulation of heat generation", "Regulation of helicase activity", "Regulation of hematopoietic progenitor cell differentiation", "Regulation of hematopoietic stem cell differentiation", "Regulation of hematopoietic stem cell proliferation", "Regulation of hemoglobin biosynthetic process", "Regulation of hemopoiesis", "Regulation of hepatic stellate cell activation", "Regulation of hepatocyte apoptotic process", "Regulation of hepatocyte proliferation", "Regulation of heterotypic cell cell adhesion", "Regulation of hexokinase activity", "Regulation of high voltage gated calcium channel activity", "Regulation of hippo signaling", "Regulation of histamine secretion by mast cell", "Regulation of histone deacetylase activity", "Regulation of histone deacetylation", "Regulation of histone h2b ubiquitination", "Regulation of histone h3 k14 acetylation", "Regulation of histone h3 k27 methylation", "Regulation of histone h3 k36 methylation", "Regulation of histone h3 k4 methylation", "Regulation of histone h3 k9 methylation", "Regulation of histone h3 k9 trimethylation", "Regulation of histone h4 acetylation", "Regulation of histone h4 k16 acetylation", "Regulation of histone methylation", "Regulation of histone modification", "Regulation of histone phosphorylation", "Regulation of histone ubiquitination", "Regulation of homophilic cell adhesion", "Regulation of homotypic cell cell adhesion", "Regulation of hormone biosynthetic process", "Regulation of hormone levels", "Regulation of hormone metabolic process", "Regulation of hormone secretion", "Regulation of humoral immune response", "Regulation of hyaluronan biosynthetic process", "Regulation of hydrogen peroxide biosynthetic process", "Regulation of hydrogen peroxide mediated programmed cell death", "Regulation of hydrogen peroxide metabolic process", "Regulation of hydrolase activity", "Regulation of i kappab phosphorylation", "Regulation of icosanoid secretion", "Regulation of immune effector process", "Regulation of immune response", "Regulation of immune system process", "Regulation of immunoglobulin production", "Regulation of inclusion body assembly", "Regulation of inflammatory response", "Regulation of inflammatory response to antigenic stimulus", "Regulation of innate immune response", "Regulation of inositol 1 4 5 trisphosphate sensitive calcium release channel activity", "Regulation of insulin like growth factor receptor signaling pathway", "Regulation of insulin receptor signaling pathway", "Regulation of insulin secretion", "Regulation of insulin secretion involved in cellular response to glucose stimulus", "Regulation of integrin activation", "Regulation of integrin mediated signaling pathway", "Regulation of interleukin 1 mediated signaling pathway", "Regulation of intestinal absorption", "Regulation of intracellular estrogen receptor signaling pathway", "Regulation of intracellular lipid transport", "Regulation of intracellular protein transport", "Regulation of intracellular signal transduction", "Regulation of intracellular steroid hormone receptor signaling pathway", "Regulation of intracellular transport", "Regulation of intrinsic apoptotic signaling pathway", "Regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Regulation of inward rectifier potassium channel activity", "Regulation of ion transmembrane transport", "Regulation of ion transport", "Regulation of ire1 mediated unfolded protein response", "Regulation of iron ion transmembrane transport", "Regulation of iron ion transport", "Regulation of isomerase activity", "Regulation of isotype switching", "Regulation of jnk cascade", "Regulation of jun kinase activity", "Regulation of keratinocyte differentiation", "Regulation of keratinocyte migration", "Regulation of keratinocyte proliferation", "Regulation of kidney development", "Regulation of l glutamate import across plasma membrane", "Regulation of lamellipodium assembly", "Regulation of lamellipodium morphogenesis", "Regulation of lamellipodium organization", "Regulation of leukocyte adhesion to vascular endothelial cell", "Regulation of leukocyte apoptotic process", "Regulation of leukocyte chemotaxis", "Regulation of leukocyte degranulation", "Regulation of leukocyte differentiation", "Regulation of leukocyte mediated cytotoxicity", "Regulation of leukocyte mediated immunity", "Regulation of leukocyte migration", "Regulation of leukocyte proliferation", "Regulation of ligase activity", "Regulation of lipase activity", "Regulation of lipid biosynthetic process", "Regulation of lipid catabolic process", "Regulation of lipid kinase activity", "Regulation of lipid localization", "Regulation of lipid metabolic process", "Regulation of lipid storage", "Regulation of lipid transport", "Regulation of lipid transporter activity", "Regulation of lipophagy", "Regulation of lipopolysaccharide mediated signaling pathway", "Regulation of lipoprotein lipase activity", "Regulation of lipoprotein metabolic process", "Regulation of lipoprotein particle clearance", "Regulation of locomotion involved in locomotory behavior", "Regulation of long chain fatty acid import across plasma membrane", "Regulation of long chain fatty acid import into cell", "Regulation of long term neuronal synaptic plasticity", "Regulation of long term synaptic depression", "Regulation of long term synaptic potentiation", "Regulation of low density lipoprotein particle clearance", "Regulation of lyase activity", "Regulation of lymphocyte activation", "Regulation of lymphocyte apoptotic process", "Regulation of lymphocyte chemotaxis", "Regulation of lymphocyte differentiation", "Regulation of lymphocyte mediated immunity", "Regulation of lymphocyte migration", "Regulation of lymphoid progenitor cell differentiation", "Regulation of lysosomal lumen ph", "Regulation of lysosomal protein catabolic process", "Regulation of lysosome organization", "Regulation of macroautophagy", "Regulation of macrophage activation", "Regulation of macrophage apoptotic process", "Regulation of macrophage chemotaxis", "Regulation of macrophage fusion", "Regulation of macrophage migration", "Regulation of macrophage proliferation", "Regulation of maintenance of sister chromatid cohesion", "Regulation of male gonad development", "Regulation of mammary gland epithelial cell proliferation", "Regulation of map kinase activity", "Regulation of mast cell activation", "Regulation of mast cell activation involved in immune response", "Regulation of matrix metallopeptidase secretion", "Regulation of mda 5 signaling pathway", "Regulation of megakaryocyte differentiation", "Regulation of meiotic cell cycle", "Regulation of meiotic cell cycle phase transition", "Regulation of meiotic nuclear division", "Regulation of membrane depolarization", "Regulation of membrane depolarization during action potential", "Regulation of membrane depolarization during cardiac muscle cell action potential", "Regulation of membrane invagination", "Regulation of membrane lipid distribution", "Regulation of membrane permeability", "Regulation of membrane potential", "Regulation of membrane protein ectodomain proteolysis", "Regulation of membrane repolarization", "Regulation of membrane repolarization during action potential", "Regulation of membrane repolarization during cardiac muscle cell action potential", "Regulation of membrane tubulation", "Regulation of mesenchymal cell proliferation", "Regulation of mesenchymal stem cell differentiation", "Regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis", "Regulation of mesoderm development", "Regulation of metal ion transport", "Regulation of metalloendopeptidase activity", "Regulation of metallopeptidase activity", "Regulation of metanephros development", "Regulation of metaphase plate congression", "Regulation of microglial cell activation", "Regulation of microtubule based movement", "Regulation of microtubule based process", "Regulation of microtubule binding", "Regulation of microtubule cytoskeleton organization", "Regulation of microtubule depolymerization", "Regulation of microtubule nucleation", "Regulation of microtubule polymerization", "Regulation of microtubule polymerization or depolymerization", "Regulation of microvillus assembly", "Regulation of microvillus length", "Regulation of microvillus organization", "Regulation of mirna catabolic process", "Regulation of mirna metabolic process", "Regulation of mirna transcription", "Regulation of mitochondrial atp synthesis coupled electron transport", "Regulation of mitochondrial dna replication", "Regulation of mitochondrial electron transport nadh to ubiquinone", "Regulation of mitochondrial fission", "Regulation of mitochondrial fusion", "Regulation of mitochondrial gene expression", "Regulation of mitochondrial membrane permeability", "Regulation of mitochondrial membrane permeability involved in apoptotic process", "Regulation of mitochondrial membrane potential", "Regulation of mitochondrial mrna stability", "Regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Regulation of mitochondrial rna catabolic process", "Regulation of mitochondrion organization", "Regulation of mitophagy", "Regulation of mitotic cell cycle", "Regulation of mitotic cell cycle phase transition", "Regulation of mitotic cell cycle spindle assembly checkpoint", "Regulation of mitotic centrosome separation", "Regulation of mitotic cytokinesis", "Regulation of mitotic nuclear division", "Regulation of mitotic recombination", "Regulation of mitotic sister chromatid segregation", "Regulation of mitotic spindle assembly", "Regulation of modification of postsynaptic structure", "Regulation of modification of synaptic structure", "Regulation of monocyte chemotaxis", "Regulation of monocyte differentiation", "Regulation of monocyte extravasation", "Regulation of mononuclear cell migration", "Regulation of monooxygenase activity", "Regulation of morphogenesis of a branching structure", "Regulation of morphogenesis of an epithelium", "Regulation of motor neuron apoptotic process", "Regulation of mrna 3 end processing", "Regulation of mrna binding", "Regulation of mrna catabolic process", "Regulation of mrna export from nucleus", "Regulation of mrna metabolic process", "Regulation of mrna polyadenylation", "Regulation of mrna processing", "Regulation of mrna splicing via spliceosome", "Regulation of mucus secretion", "Regulation of multicellular organism growth", "Regulation of multicellular organismal development", "Regulation of muscle adaptation", "Regulation of muscle cell differentiation", "Regulation of muscle contraction", "Regulation of muscle hypertrophy", "Regulation of muscle organ development", "Regulation of muscle system process", "Regulation of myelination", "Regulation of myeloid cell apoptotic process", "Regulation of myeloid cell differentiation", "Regulation of myeloid leukocyte differentiation", "Regulation of myeloid leukocyte mediated immunity", "Regulation of myoblast differentiation", "Regulation of myoblast fusion", "Regulation of myoblast proliferation", "Regulation of myosin light chain phosphatase activity", "Regulation of myotube differentiation", "Regulation of nad p h oxidase activity", "Regulation of nadp metabolic process", "Regulation of natural killer cell activation", "Regulation of natural killer cell mediated immune response to tumor cell", "Regulation of natural killer cell mediated immunity", "Regulation of necrotic cell death", "Regulation of nervous system development", "Regulation of nervous system process", "Regulation of neural precursor cell proliferation", "Regulation of neuroblast proliferation", "Regulation of neurogenesis", "Regulation of neuromuscular junction development", "Regulation of neuron differentiation", "Regulation of neuron migration", "Regulation of neuron projection arborization", "Regulation of neuron projection development", "Regulation of neuron projection regeneration", "Regulation of neuronal action potential", "Regulation of neuronal synaptic plasticity", "Regulation of neurotransmitter levels", "Regulation of neurotransmitter receptor activity", "Regulation of neurotransmitter transport", "Regulation of neurotransmitter uptake", "Regulation of neurotrophin trk receptor signaling pathway", "Regulation of neutrophil chemotaxis", "Regulation of neutrophil migration", "Regulation of nik nf kappab signaling", "Regulation of nitric oxide mediated signal transduction", "Regulation of nitric oxide metabolic process", "Regulation of nitric oxide synthase activity", "Regulation of nk t cell activation", "Regulation of nk t cell differentiation", "Regulation of nmda receptor activity", "Regulation of non motile cilium assembly", "Regulation of notch signaling pathway", "Regulation of nuclear cell cycle dna replication", "Regulation of nuclear division", "Regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Regulation of nuclear transcribed mrna poly a tail shortening", "Regulation of nuclease activity", "Regulation of nucleobase containing compound transport", "Regulation of nucleocytoplasmic transport", "Regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Regulation of nucleotide binding oligomerization domain containing signaling pathway", "Regulation of nucleotide biosynthetic process", "Regulation of nucleotide metabolic process", "Regulation of oligodendrocyte differentiation", "Regulation of oocyte maturation", "Regulation of opsonization", "Regulation of organ growth", "Regulation of organelle assembly", "Regulation of organelle organization", "Regulation of organelle transport along microtubule", "Regulation of organic acid transport", "Regulation of ossification", "Regulation of osteoblast differentiation", "Regulation of osteoblast proliferation", "Regulation of osteoclast differentiation", "Regulation of oxidative phosphorylation", "Regulation of oxidative stress induced cell death", "Regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Regulation of oxidoreductase activity", "Regulation of p38mapk cascade", "Regulation of pancreatic juice secretion", "Regulation of pattern recognition receptor signaling pathway", "Regulation of penile erection", "Regulation of peptidase activity", "Regulation of peptide transport", "Regulation of peptidyl lysine acetylation", "Regulation of peptidyl serine phosphorylation", "Regulation of peptidyl serine phosphorylation of stat protein", "Regulation of peptidyl threonine phosphorylation", "Regulation of peptidyl tyrosine phosphorylation", "Regulation of perk mediated unfolded protein response", "Regulation of peroxisome proliferator activated receptor signaling pathway", "Regulation of ph", "Regulation of phagocytosis", "Regulation of phenotypic switching", "Regulation of phosphatase activity", "Regulation of phosphatidylcholine biosynthetic process", "Regulation of phosphatidylcholine metabolic process", "Regulation of phosphatidylinositol 3 kinase activity", "Regulation of phosphatidylinositol 3 kinase signaling", "Regulation of phosphatidylinositol dephosphorylation", "Regulation of phospholipase a2 activity", "Regulation of phospholipase activity", "Regulation of phospholipase c activity", "Regulation of phospholipid biosynthetic process", "Regulation of phospholipid catabolic process", "Regulation of phospholipid metabolic process", "Regulation of phospholipid translocation", "Regulation of phospholipid transport", "Regulation of phosphoprotein phosphatase activity", "Regulation of phosphorus metabolic process", "Regulation of pigmentation", "Regulation of pinocytosis", "Regulation of plasma lipoprotein particle levels", "Regulation of plasma membrane organization", "Regulation of plasminogen activation", "Regulation of platelet activation", "Regulation of platelet aggregation", "Regulation of platelet derived growth factor receptor beta signaling pathway", "Regulation of platelet derived growth factor receptor signaling pathway", "Regulation of podosome assembly", "Regulation of polysaccharide metabolic process", "Regulation of positive chemotaxis", "Regulation of post translational protein modification", "Regulation of postsynapse organization", "Regulation of postsynaptic density organization", "Regulation of postsynaptic membrane neurotransmitter receptor levels", "Regulation of postsynaptic membrane potential", "Regulation of postsynaptic neurotransmitter receptor activity", "Regulation of postsynaptic neurotransmitter receptor internalization", "Regulation of potassium ion export across plasma membrane", "Regulation of potassium ion import", "Regulation of potassium ion transmembrane transporter activity", "Regulation of potassium ion transport", "Regulation of presynapse organization", "Regulation of presynaptic cytosolic calcium ion concentration", "Regulation of pro b cell differentiation", "Regulation of production of molecular mediator of immune response", "Regulation of production of small rna involved in gene silencing by rna", "Regulation of programmed necrotic cell death", "Regulation of prostaglandin secretion", "Regulation of proteasomal protein catabolic process", "Regulation of proteasomal ubiquitin dependent protein catabolic process", "Regulation of protein acetylation", "Regulation of protein adp ribosylation", "Regulation of protein autophosphorylation", "Regulation of protein autoubiquitination", "Regulation of protein binding", "Regulation of protein catabolic process", "Regulation of protein catabolic process in the vacuole", "Regulation of protein complex stability", "Regulation of protein containing complex assembly", "Regulation of protein containing complex disassembly", "Regulation of protein deacetylation", "Regulation of protein dephosphorylation", "Regulation of protein depolymerization", "Regulation of protein deubiquitination", "Regulation of protein exit from endoplasmic reticulum", "Regulation of protein export from nucleus", "Regulation of protein folding", "Regulation of protein glycosylation", "Regulation of protein import", "Regulation of protein k63 linked ubiquitination", "Regulation of protein kinase a signaling", "Regulation of protein kinase activity", "Regulation of protein kinase c activity", "Regulation of protein kinase c signaling", "Regulation of protein lipidation", "Regulation of protein localization", "Regulation of protein localization to cell cortex", "Regulation of protein localization to cell periphery", "Regulation of protein localization to cell surface", "Regulation of protein localization to centrosome", "Regulation of protein localization to chromatin", "Regulation of protein localization to chromosome telomeric region", "Regulation of protein localization to cilium", "Regulation of protein localization to endosome", "Regulation of protein localization to membrane", "Regulation of protein localization to nucleolus", "Regulation of protein localization to nucleus", "Regulation of protein localization to plasma membrane", "Regulation of protein localization to synapse", "Regulation of protein maturation", "Regulation of protein modification by small protein conjugation or removal", "Regulation of protein modification process", "Regulation of protein monoubiquitination", "Regulation of protein neddylation", "Regulation of protein phosphorylation", "Regulation of protein polymerization", "Regulation of protein polyubiquitination", "Regulation of protein secretion", "Regulation of protein serine threonine kinase activity", "Regulation of protein stability", "Regulation of protein sumoylation", "Regulation of protein targeting", "Regulation of protein targeting to membrane", "Regulation of protein tyrosine kinase activity", "Regulation of protein tyrosine phosphatase activity", "Regulation of proteolysis", "Regulation of proton transport", "Regulation of rab protein signal transduction", "Regulation of rac protein signal transduction", "Regulation of ras protein signal transduction", "Regulation of reactive oxygen species biosynthetic process", "Regulation of reactive oxygen species metabolic process", "Regulation of receptor binding", "Regulation of receptor catabolic process", "Regulation of receptor clustering", "Regulation of receptor internalization", "Regulation of receptor localization to synapse", "Regulation of receptor mediated endocytosis", "Regulation of receptor mediated endocytosis involved in cholesterol transport", "Regulation of receptor recycling", "Regulation of receptor signaling pathway via stat", "Regulation of regulated secretory pathway", "Regulation of relaxation of muscle", "Regulation of release of cytochrome c from mitochondria", "Regulation of release of sequestered calcium ion into cytosol", "Regulation of removal of superoxide radicals", "Regulation of renal system process", "Regulation of reproductive process", "Regulation of respiratory burst", "Regulation of respiratory gaseous exchange", "Regulation of respiratory gaseous exchange by nervous system process", "Regulation of respiratory system process", "Regulation of response to biotic stimulus", "Regulation of response to cytokine stimulus", "Regulation of response to dna damage stimulus", "Regulation of response to endoplasmic reticulum stress", "Regulation of response to external stimulus", "Regulation of response to extracellular stimulus", "Regulation of response to food", "Regulation of response to interferon gamma", "Regulation of response to osmotic stress", "Regulation of response to oxidative stress", "Regulation of response to reactive oxygen species", "Regulation of response to stress", "Regulation of response to tumor cell", "Regulation of response to wounding", "Regulation of retinal ganglion cell axon guidance", "Regulation of retinoic acid receptor signaling pathway", "Regulation of retrograde protein transport er to cytosol", "Regulation of retrograde transport endosome to golgi", "Regulation of rho dependent protein serine threonine kinase activity", "Regulation of rho protein signal transduction", "Regulation of rhodopsin mediated signaling pathway", "Regulation of ribonuclease activity", "Regulation of ribosome biogenesis", "Regulation of rig i signaling pathway", "Regulation of rna binding", "Regulation of rna export from nucleus", "Regulation of rna polymerase ii regulatory region sequence specific dna binding", "Regulation of rna polymerase ii transcription preinitiation complex assembly", "Regulation of rna splicing", "Regulation of rrna processing", "Regulation of ruffle assembly", "Regulation of ryanodine sensitive calcium release channel activity", "Regulation of sarcomere organization", "Regulation of secondary heart field cardioblast proliferation", "Regulation of secondary metabolic process", "Regulation of secretion", "Regulation of sensory perception", "Regulation of sequestering of triglyceride", "Regulation of sequestering of zinc ion", "Regulation of short term neuronal synaptic plasticity", "Regulation of signal transduction by p53 class mediator", "Regulation of signaling receptor activity", "Regulation of sister chromatid cohesion", "Regulation of skeletal muscle adaptation", "Regulation of skeletal muscle cell differentiation", "Regulation of skeletal muscle cell proliferation", "Regulation of skeletal muscle contraction", "Regulation of skeletal muscle contraction by calcium ion signaling", "Regulation of skeletal muscle fiber development", "Regulation of skeletal muscle tissue development", "Regulation of skeletal muscle tissue growth", "Regulation of smad protein complex assembly", "Regulation of smad protein signal transduction", "Regulation of small gtpase mediated signal transduction", "Regulation of small molecule metabolic process", "Regulation of smooth muscle cell chemotaxis", "Regulation of smooth muscle cell differentiation", "Regulation of smooth muscle contraction", "Regulation of smoothened signaling pathway", "Regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Regulation of snare complex assembly", "Regulation of snrna transcription by rna polymerase ii", "Regulation of sodium ion transmembrane transport", "Regulation of sodium ion transport", "Regulation of sodium proton antiporter activity", "Regulation of sphingolipid biosynthetic process", "Regulation of spindle assembly", "Regulation of spindle organization", "Regulation of spontaneous synaptic transmission", "Regulation of sprouting angiogenesis", "Regulation of srebp signaling pathway", "Regulation of stem cell differentiation", "Regulation of stem cell population maintenance", "Regulation of stem cell proliferation", "Regulation of steroid biosynthetic process", "Regulation of steroid hormone biosynthetic process", "Regulation of steroid hormone secretion", "Regulation of steroid metabolic process", "Regulation of sterol transport", "Regulation of store operated calcium channel activity", "Regulation of stress activated protein kinase signaling cascade", "Regulation of stress granule assembly", "Regulation of striated muscle cell differentiation", "Regulation of striated muscle contraction", "Regulation of substrate adhesion dependent cell spreading", "Regulation of sulfur metabolic process", "Regulation of superoxide anion generation", "Regulation of superoxide dismutase activity", "Regulation of superoxide metabolic process", "Regulation of supramolecular fiber organization", "Regulation of synapse assembly", "Regulation of synapse maturation", "Regulation of synapse structural plasticity", "Regulation of synapse structure or activity", "Regulation of synaptic plasticity", "Regulation of synaptic transmission dopaminergic", "Regulation of synaptic transmission gabaergic", "Regulation of synaptic transmission glutamatergic", "Regulation of synaptic vesicle clustering", "Regulation of synaptic vesicle cycle", "Regulation of synaptic vesicle endocytosis", "Regulation of synaptic vesicle exocytosis", "Regulation of synaptic vesicle priming", "Regulation of synaptic vesicle recycling", "Regulation of syncytium formation by plasma membrane fusion", "Regulation of system process", "Regulation of systemic arterial blood pressure", "Regulation of systemic arterial blood pressure by endothelin", "Regulation of systemic arterial blood pressure by hormone", "Regulation of systemic arterial blood pressure by norepinephrine epinephrine", "Regulation of systemic arterial blood pressure by renin angiotensin", "Regulation of systemic arterial blood pressure mediated by a chemical signal", "Regulation of t cell activation", "Regulation of t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell", "Regulation of t cell apoptotic process", "Regulation of t cell chemotaxis", "Regulation of t cell differentiation", "Regulation of t cell differentiation in thymus", "Regulation of t cell mediated cytotoxicity", "Regulation of t cell mediated immune response to tumor cell", "Regulation of t cell mediated immunity", "Regulation of t cell migration", "Regulation of t cell proliferation", "Regulation of t cell receptor signaling pathway", "Regulation of t circle formation", "Regulation of t helper 1 cell differentiation", "Regulation of t helper 1 type immune response", "Regulation of t helper 2 cell differentiation", "Regulation of t helper cell differentiation", "Regulation of tau protein kinase activity", "Regulation of telomerase activity", "Regulation of telomere capping", "Regulation of telomere maintenance", "Regulation of telomere maintenance via telomere lengthening", "Regulation of tetrapyrrole metabolic process", "Regulation of the force of heart contraction", "Regulation of thymocyte apoptotic process", "Regulation of tissue remodeling", "Regulation of tolerance induction", "Regulation of toll like receptor 2 signaling pathway", "Regulation of toll like receptor 3 signaling pathway", "Regulation of toll like receptor 4 signaling pathway", "Regulation of toll like receptor 7 signaling pathway", "Regulation of toll like receptor 9 signaling pathway", "Regulation of toll like receptor signaling pathway", "Regulation of tooth mineralization", "Regulation of tor signaling", "Regulation of torc2 signaling", "Regulation of trail activated apoptotic signaling pathway", "Regulation of trans synaptic signaling", "Regulation of transcription by glucose", "Regulation of transcription by rna polymerase i", "Regulation of transcription by rna polymerase iii", "Regulation of transcription elongation from rna polymerase ii promoter", "Regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Regulation of transcription from rna polymerase ii promoter in response to oxidative stress", "Regulation of transcription from rna polymerase ii promoter involved in heart development", "Regulation of transcription involved in g1 s transition of mitotic cell cycle", "Regulation of transcription of nucleolar large rrna by rna polymerase i", "Regulation of transcription regulatory region dna binding", "Regulation of transferase activity", "Regulation of transforming growth factor beta activation", "Regulation of transforming growth factor beta1 production", "Regulation of translation at synapse modulating synaptic transmission", "Regulation of translation in response to endoplasmic reticulum stress", "Regulation of translation in response to stress", "Regulation of translation initiation in response to endoplasmic reticulum stress", "Regulation of translational elongation", "Regulation of translational fidelity", "Regulation of translational initiation", "Regulation of translational initiation by eif2 alpha phosphorylation", "Regulation of translational initiation in response to stress", "Regulation of translational termination", "Regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Regulation of transmembrane transport", "Regulation of transmission of nerve impulse", "Regulation of transport", "Regulation of transporter activity", "Regulation of transposition", "Regulation of triglyceride biosynthetic process", "Regulation of triglyceride catabolic process", "Regulation of triglyceride metabolic process", "Regulation of tube size", "Regulation of tumor necrosis factor mediated signaling pathway", "Regulation of type b pancreatic cell development", "Regulation of type b pancreatic cell proliferation", "Regulation of type i interferon mediated signaling pathway", "Regulation of ubiquitin dependent protein catabolic process", "Regulation of ubiquitin protein ligase activity", "Regulation of ubiquitin protein transferase activity", "Regulation of ubiquitin specific protease activity", "Regulation of unsaturated fatty acid biosynthetic process", "Regulation of urine volume", "Regulation of vacuole organization", "Regulation of vascular associated smooth muscle cell differentiation", "Regulation of vascular associated smooth muscle contraction", "Regulation of vascular endothelial growth factor receptor signaling pathway", "Regulation of vascular permeability", "Regulation of vascular wound healing", "Regulation of vasculature development", "Regulation of vasculogenesis", "Regulation of vasoconstriction", "Regulation of ventricular cardiac muscle cell action potential", "Regulation of very low density lipoprotein particle clearance", "Regulation of vesicle fusion", "Regulation of vesicle mediated transport", "Regulation of vesicle size", "Regulation of viral entry into host cell", "Regulation of viral genome replication", "Regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Regulation of viral process", "Regulation of viral transcription", "Regulation of vitamin d receptor signaling pathway", "Regulation of vitamin metabolic process", "Regulation of voltage gated calcium channel activity", "Regulation of voltage gated sodium channel activity", "Regulation of water loss via skin", "Regulation of wnt signaling pathway", "Regulation of wnt signaling pathway involved in heart development", "Regulation of wound healing", "Regulation of wound healing spreading of epidermal cells", "Regulation of xenophagy", "Regulatory t cell differentiation", "Relaxation of cardiac muscle", "Relaxation of muscle", "Release of cytochrome c from mitochondria", "Release of sequestered calcium ion into cytosol by endoplasmic reticulum", "Renal absorption", "Renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure", "Renal filtration", "Renal sodium excretion", "Renal sodium ion absorption", "Renal sodium ion transport", "Renal system process", "Renal system process involved in regulation of systemic arterial blood pressure", "Renal system vasculature development", "Renal system vasculature morphogenesis", "Renal tubular secretion", "Renal tubule development", "Renal vesicle development", "Renal vesicle formation", "Renal water homeostasis", "Replacement ossification", "Replication born double strand break repair via sister chromatid exchange", "Replication fork processing", "Replication fork protection", "Replicative senescence", "Reproduction", "Reproductive behavior", "Reproductive system development", "Rescue of stalled ribosome", "Resolution of meiotic recombination intermediates", "Resolution of recombination intermediates", "Respiratory burst", "Respiratory burst involved in defense response", "Respiratory burst involved in inflammatory response", "Respiratory chain complex iii assembly", "Respiratory chain complex iv assembly", "Respiratory electron transport chain", "Respiratory gaseous exchange by respiratory system", "Respiratory system development", "Respiratory system process", "Response to abiotic stimulus", "Response to acetylcholine", "Response to acid chemical", "Response to acidic ph", "Response to actinomycin d", "Response to activity", "Response to alcohol", "Response to aldosterone", "Response to alkaloid", "Response to amine", "Response to amino acid starvation", "Response to ammonium ion", "Response to amphetamine", "Response to amyloid beta", "Response to angiotensin", "Response to antibiotic", "Response to arsenic containing substance", "Response to arsenite ion", "Response to atp", "Response to auditory stimulus", "Response to axon injury", "Response to bacterium", "Response to bmp", "Response to cadmium ion", "Response to caffeine", "Response to calcium ion", "Response to camp", "Response to camptothecin", "Response to carbohydrate", "Response to catecholamine", "Response to cell cycle checkpoint signaling", "Response to cgmp", "Response to chemokine", "Response to cholesterol", "Response to cisplatin", "Response to cobalt ion", "Response to cocaine", "Response to cold", "Response to copper ion", "Response to corticosteroid", "Response to corticosterone", "Response to cortisol", "Response to cycloheximide", "Response to cytokine", "Response to dexamethasone", "Response to dietary excess", "Response to dopamine", "Response to dsrna", "Response to electrical stimulus", "Response to endogenous stimulus", "Response to endoplasmic reticulum stress", "Response to epidermal growth factor", "Response to epinephrine", "Response to estradiol", "Response to estrogen", "Response to ethanol", "Response to ether", "Response to extracellular stimulus", "Response to fatty acid", "Response to fibroblast growth factor", "Response to fluid shear stress", "Response to folic acid", "Response to follicle stimulating hormone", "Response to food", "Response to fungus", "Response to gamma radiation", "Response to glucagon", "Response to glycoprotein", "Response to glycoside", "Response to gonadotropin", "Response to granulocyte macrophage colony stimulating factor", "Response to growth factor", "Response to growth hormone", "Response to heat", "Response to heparin", "Response to hepatocyte growth factor", "Response to herbicide", "Response to histamine", "Response to hormone", "Response to hydrogen peroxide", "Response to hydroperoxide", "Response to hydrostatic pressure", "Response to hydroxyurea", "Response to hyperoxia", "Response to immobilization stress", "Response to increased oxygen levels", "Response to indole 3 methanol", "Response to inorganic substance", "Response to insecticide", "Response to insulin", "Response to interferon alpha", "Response to interferon beta", "Response to interferon gamma", "Response to interleukin 1", "Response to interleukin 12", "Response to interleukin 18", "Response to interleukin 3", "Response to interleukin 4", "Response to interleukin 6", "Response to interleukin 7", "Response to ionizing radiation", "Response to iron ii ion", "Response to iron ion", "Response to ischemia", "Response to isoquinoline alkaloid", "Response to ketone", "Response to l ascorbic acid", "Response to l glutamate", "Response to l phenylalanine derivative", "Response to lead ion", "Response to lectin", "Response to leptin", "Response to leucine", "Response to leukemia inhibitory factor", "Response to light intensity", "Response to light stimulus", "Response to lipid", "Response to lipoteichoic acid", "Response to lithium ion", "Response to luteinizing hormone", "Response to magnesium ion", "Response to manganese ion", "Response to mechanical stimulus", "Response to mercury ion", "Response to metal ion", "Response to methylmercury", "Response to mineralocorticoid", "Response to misfolded protein", "Response to mitochondrial depolarisation", "Response to molecule of bacterial origin", "Response to monosaccharide", "Response to muramyl dipeptide", "Response to muscle activity", "Response to muscle stretch", "Response to nerve growth factor", "Response to nicotine", "Response to nitric oxide", "Response to nitrogen compound", "Response to nitrosative stress", "Response to nutrient", "Response to oleic acid", "Response to organic cyclic compound", "Response to osmotic stress", "Response to oxidative stress", "Response to oxygen containing compound", "Response to oxygen glucose deprivation", "Response to oxygen levels", "Response to oxygen radical", "Response to pain", "Response to parathyroid hormone", "Response to peptide", "Response to peptide hormone", "Response to peptidoglycan", "Response to ph", "Response to phorbol 13 acetate 12 myristate", "Response to platelet derived growth factor", "Response to potassium ion", "Response to progesterone", "Response to prostaglandin", "Response to prostaglandin e", "Response to purine containing compound", "Response to radiation", "Response to reactive oxygen species", "Response to redox state", "Response to retinoic acid", "Response to salt", "Response to salt stress", "Response to selenium ion", "Response to sodium arsenite", "Response to sorbitol", "Response to starvation", "Response to steroid hormone", "Response to sterol", "Response to sterol depletion", "Response to temperature stimulus", "Response to testosterone", "Response to thyroglobulin triiodothyronine", "Response to thyroid hormone", "Response to thyroxine", "Response to topologically incorrect protein", "Response to toxic substance", "Response to transforming growth factor beta", "Response to tumor cell", "Response to tumor necrosis factor", "Response to type i interferon", "Response to uv", "Response to uv a", "Response to uv b", "Response to uv c", "Response to virus", "Response to vitamin", "Response to vitamin a", "Response to vitamin d", "Response to vitamin k", "Response to water", "Response to wounding", "Response to x ray", "Response to xenobiotic stimulus", "Response to zinc ion", "Reticulophagy", "Retina development in camera type eye", "Retina homeostasis", "Retina layer formation", "Retina morphogenesis in camera type eye", "Retina vasculature development in camera type eye", "Retina vasculature morphogenesis in camera type eye", "Retinal cell apoptotic process", "Retinal cell programmed cell death", "Retinal cone cell differentiation", "Retinal ganglion cell axon guidance", "Retinal metabolic process", "Retinal pigment epithelium development", "Retinal rod cell development", "Retinal rod cell differentiation", "Retinoic acid metabolic process", "Retinoic acid receptor signaling pathway", "Retinol metabolic process", "Retrograde axonal transport", "Retrograde trans synaptic signaling", "Retrograde trans synaptic signaling by lipid", "Retrograde transport endosome to golgi", "Retrograde transport vesicle recycling within golgi", "Retrograde vesicle mediated transport golgi to endoplasmic reticulum", "Reverse cholesterol transport", "Reversible differentiation", "Rho protein signal transduction", "Rhodopsin mediated signaling pathway", "Rhythmic behavior", "Rhythmic process", "Riboflavin metabolic process", "Ribonucleoprotein complex biogenesis", "Ribonucleoprotein complex disassembly", "Ribonucleoprotein complex localization", "Ribonucleoprotein complex subunit organization", "Ribonucleoside catabolic process", "Ribonucleoside diphosphate biosynthetic process", "Ribonucleoside diphosphate catabolic process", "Ribonucleoside diphosphate metabolic process", "Ribonucleoside metabolic process", "Ribonucleoside monophosphate biosynthetic process", "Ribonucleoside monophosphate catabolic process", "Ribonucleoside monophosphate metabolic process", "Ribonucleoside triphosphate biosynthetic process", "Ribonucleoside triphosphate metabolic process", "Ribonucleotide catabolic process", "Ribose phosphate biosynthetic process", "Ribose phosphate metabolic process", "Ribosomal large subunit assembly", "Ribosomal large subunit biogenesis", "Ribosomal large subunit export from nucleus", "Ribosomal small subunit assembly", "Ribosomal small subunit biogenesis", "Ribosomal small subunit export from nucleus", "Ribosomal subunit export from nucleus", "Ribosome assembly", "Ribosome associated ubiquitin dependent protein catabolic process", "Ribosome biogenesis", "Ribosome disassembly", "Rig i signaling pathway", "Righting reflex", "Rna 3 end processing", "Rna 3 uridylation", "Rna 5 end processing", "Rna capping", "Rna catabolic process", "Rna decapping", "Rna dependent dna biosynthetic process", "Rna destabilization", "Rna export from nucleus", "Rna guanine n7 methylation", "Rna import into mitochondrion", "Rna interference", "Rna localization", "Rna mediated gene silencing by inhibition of translation", "Rna methylation", "Rna modification", "Rna phosphodiester bond hydrolysis", "Rna phosphodiester bond hydrolysis endonucleolytic", "Rna phosphodiester bond hydrolysis exonucleolytic", "Rna polyadenylation", "Rna polymerase i preinitiation complex assembly", "Rna polymerase ii preinitiation complex assembly", "Rna processing", "Rna secondary structure unwinding", "Rna splicing", "Rna splicing via endonucleolytic cleavage and ligation", "Rna splicing via transesterification reactions", "Rna stabilization", "Rna surveillance", "Roof of mouth development", "Roundabout signaling pathway", "Rrna 3 end processing", "Rrna 5 end processing", "Rrna base methylation", "Rrna catabolic process", "Rrna metabolic process", "Rrna methylation", "Rrna modification", "Rrna pseudouridine synthesis", "Rrna transcription", "Rrna transport", "Ruffle assembly", "Ruffle organization", "S adenosylmethionine cycle", "S adenosylmethionine metabolic process", "Salivary gland development", "Sarcomere organization", "Sarcoplasmic reticulum calcium ion transport", "Satellite cell activation involved in skeletal muscle regeneration", "Scarna localization to cajal body", "Scf dependent proteasomal ubiquitin dependent protein catabolic process", "Schwann cell development", "Schwann cell differentiation", "Schwann cell proliferation", "Sebaceous gland development", "Second messenger mediated signaling", "Secondary alcohol metabolic process", "Secondary heart field specification", "Secondary metabolic process", "Secondary metabolite biosynthetic process", "Secondary palate development", "Secretion", "Secretion by tissue", "Secretory granule localization", "Secretory granule organization", "Segment specification", "Segmentation", "Selective autophagy", "Self proteolysis", "Semaphorin plexin signaling pathway", "Semaphorin plexin signaling pathway involved in neuron projection guidance", "Semi lunar valve development", "Seminiferous tubule development", "Sensory organ development", "Sensory organ morphogenesis", "Sensory perception", "Sensory perception of light stimulus", "Sensory perception of mechanical stimulus", "Sensory perception of pain", "Sensory system development", "Septum primum development", "Sequestering of actin monomers", "Sequestering of calcium ion", "Sequestering of iron ion", "Sequestering of metal ion", "Sequestering of triglyceride", "Sequestering of zinc ion", "Serine family amino acid biosynthetic process", "Serine family amino acid catabolic process", "Serine family amino acid metabolic process", "Serine phosphorylation of stat protein", "Serine transport", "Serotonin metabolic process", "Sertoli cell development", "Sertoli cell differentiation", "Sex determination", "Sex differentiation", "Short chain fatty acid catabolic process", "Short chain fatty acid metabolic process", "Short term memory", "Signal complex assembly", "Signal peptide processing", "Signal release", "Signal transduction by p53 class mediator", "Signal transduction in absence of ligand", "Signal transduction in response to dna damage", "Signal transduction involved in regulation of gene expression", "Signaling receptor ligand precursor processing", "Single fertilization", "Single strand break repair", "Single stranded viral rna replication via double stranded dna intermediate", "Sister chromatid cohesion", "Sister chromatid segregation", "Skeletal muscle acetylcholine gated channel clustering", "Skeletal muscle adaptation", "Skeletal muscle cell differentiation", "Skeletal muscle cell proliferation", "Skeletal muscle contraction", "Skeletal muscle fiber differentiation", "Skeletal muscle organ development", "Skeletal muscle satellite cell activation", "Skeletal muscle tissue growth", "Skeletal muscle tissue regeneration", "Skeletal myofibril assembly", "Skeletal system development", "Skeletal system morphogenesis", "Skin development", "Skin epidermis development", "Skin morphogenesis", "Sleep", "Smad protein complex assembly", "Smad protein signal transduction", "Small gtpase mediated signal transduction", "Small molecule biosynthetic process", "Small molecule catabolic process", "Small molecule metabolic process", "Small nucleolar ribonucleoprotein complex assembly", "Small rna loading onto risc", "Smooth muscle adaptation", "Smooth muscle cell apoptotic process", "Smooth muscle cell chemotaxis", "Smooth muscle cell differentiation", "Smooth muscle cell migration", "Smooth muscle cell proliferation", "Smooth muscle contraction", "Smooth muscle tissue development", "Smoothened signaling pathway", "Smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Snare complex assembly", "Sno s rna metabolic process", "Sno s rna processing", "Snorna localization", "Snrna metabolic process", "Snrna modification", "Snrna processing", "Snrna transcription", "Snrna transcription by rna polymerase ii", "Snrna transport", "Sodium independent organic anion transport", "Sodium ion export across plasma membrane", "Sodium ion homeostasis", "Sodium ion import across plasma membrane", "Sodium ion transmembrane transport", "Sodium ion transport", "Somatic diversification of immune receptors", "Somatic diversification of immune receptors via somatic mutation", "Somatic diversification of immunoglobulins", "Somatic diversification of immunoglobulins involved in immune response", "Somatic diversification of t cell receptor genes", "Somatic stem cell population maintenance", "Somite development", "Somite rostral caudal axis specification", "Somitogenesis", "Specification of animal organ identity", "Specification of symmetry", "Sperm capacitation", "Sperm dna condensation", "Sperm egg recognition", "Sperm motility", "Spermatid differentiation", "Spermatid nucleus differentiation", "Spermatogenesis exchange of chromosomal proteins", "Spermidine metabolic process", "Spermine metabolic process", "Sphingoid metabolic process", "Sphingolipid biosynthetic process", "Sphingolipid mediated signaling pathway", "Sphingolipid metabolic process", "Sphingolipid translocation", "Sphingomyelin biosynthetic process", "Sphingomyelin catabolic process", "Sphingomyelin metabolic process", "Sphingosine biosynthetic process", "Spinal cord development", "Spinal cord motor neuron differentiation", "Spindle assembly", "Spindle assembly involved in female meiosis", "Spindle elongation", "Spindle localization", "Spindle midzone assembly", "Spindle organization", "Spleen development", "Spliceosomal complex assembly", "Spliceosomal conformational changes to generate catalytic conformation", "Spliceosomal snrnp assembly", "Spliceosomal tri snrnp complex assembly", "Spontaneous synaptic transmission", "Sprouting angiogenesis", "Srp dependent cotranslational protein targeting to membrane", "Srp dependent cotranslational protein targeting to membrane signal sequence recognition", "Srp dependent cotranslational protein targeting to membrane translocation", "Startle response", "Stem cell differentiation", "Stem cell division", "Stem cell proliferation", "Steroid biosynthetic process", "Steroid catabolic process", "Steroid esterification", "Steroid hormone biosynthetic process", "Steroid hormone mediated signaling pathway", "Steroid hormone secretion", "Steroid metabolic process", "Sterol biosynthetic process", "Sterol homeostasis", "Sterol import", "Sterol metabolic process", "Sterol transport", "Stress activated protein kinase signaling cascade", "Stress fiber assembly", "Stress granule assembly", "Stress granule disassembly", "Stress induced premature senescence", "Stress response to metal ion", "Striated muscle adaptation", "Striated muscle cell apoptotic process", "Striated muscle cell development", "Striated muscle cell differentiation", "Striated muscle cell proliferation", "Striated muscle contraction", "Striatum development", "Subpallium development", "Substantia nigra development", "Substrate adhesion dependent cell spreading", "Substrate dependent cell migration", "Substrate dependent cell migration cell extension", "Substrate independent telencephalic tangential migration", "Subtelomeric heterochromatin assembly", "Succinate metabolic process", "Succinate transmembrane transport", "Succinyl coa metabolic process", "Suckling behavior", "Sugar mediated signaling pathway", "Sulfate transport", "Sulfur amino acid biosynthetic process", "Sulfur amino acid catabolic process", "Sulfur amino acid metabolic process", "Sulfur compound biosynthetic process", "Sulfur compound catabolic process", "Sulfur compound metabolic process", "Sulfur compound transport", "Superoxide anion generation", "Superoxide metabolic process", "Suppression of viral release by host", "Supramolecular fiber organization", "Sympathetic ganglion development", "Sympathetic nervous system development", "Synapse assembly", "Synapse maturation", "Synapse organization", "Synapse pruning", "Synaptic assembly at neuromuscular junction", "Synaptic membrane adhesion", "Synaptic signaling", "Synaptic transmission dopaminergic", "Synaptic transmission gabaergic", "Synaptic transmission glutamatergic", "Synaptic vesicle budding", "Synaptic vesicle clustering", "Synaptic vesicle cytoskeletal transport", "Synaptic vesicle docking", "Synaptic vesicle endosomal processing", "Synaptic vesicle exocytosis", "Synaptic vesicle localization", "Synaptic vesicle maturation", "Synaptic vesicle membrane organization", "Synaptic vesicle priming", "Synaptic vesicle recycling", "Synaptic vesicle recycling via endosome", "Synaptic vesicle transport", "Synaptic vesicle uncoating", "Synaptonemal complex organization", "Syncytium formation", "T cell activation", "T cell activation involved in immune response", "T cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell", "T cell apoptotic process", "T cell chemotaxis", "T cell cytokine production", "T cell differentiation", "T cell differentiation in thymus", "T cell differentiation involved in immune response", "T cell extravasation", "T cell homeostasis", "T cell lineage commitment", "T cell mediated cytotoxicity", "T cell mediated immune response to tumor cell", "T cell mediated immunity", "T cell migration", "T cell proliferation", "T cell proliferation involved in immune response", "T cell receptor signaling pathway", "T cell selection", "T cell tolerance induction", "T helper 1 cell differentiation", "T helper 1 type immune response", "T helper 17 type immune response", "T helper 2 cell differentiation", "T helper cell lineage commitment", "T tubule organization", "Tail anchored membrane protein insertion into er membrane", "Tangential migration from the subventricular zone to the olfactory bulb", "Taurine transport", "Taxis", "Telencephalon development", "Telencephalon glial cell migration", "Telencephalon regionalization", "Telomerase holoenzyme complex assembly", "Telomerase rna localization", "Telomere capping", "Telomere maintenance", "Telomere maintenance in response to dna damage", "Telomere maintenance via recombination", "Telomere maintenance via semi conservative replication", "Telomere maintenance via telomere lengthening", "Telomere organization", "Telomeric d loop disassembly", "Telomeric loop disassembly", "Temperature homeostasis", "Terminal button organization", "Termination of rna polymerase ii transcription", "Terpenoid biosynthetic process", "Terpenoid metabolic process", "Tertiary alcohol metabolic process", "Tetrahydrobiopterin metabolic process", "Tetrahydrofolate biosynthetic process", "Tetrahydrofolate interconversion", "Tetrahydrofolate metabolic process", "Tetrapyrrole biosynthetic process", "Tetrapyrrole catabolic process", "Tetrapyrrole metabolic process", "Thalamus development", "Thioester biosynthetic process", "Thioester metabolic process", "Thorax and anterior abdomen determination", "Threonine catabolic process", "Threonine metabolic process", "Thrombin activated receptor signaling pathway", "Thrombopoietin mediated signaling pathway", "Thymocyte apoptotic process", "Thymus development", "Thyroid gland development", "Thyroid hormone generation", "Thyroid hormone mediated signaling pathway", "Thyroid hormone metabolic process", "Tight junction organization", "Tissue development", "Tissue migration", "Tissue morphogenesis", "Tissue regeneration", "Tissue remodeling", "Tolerance induction", "Tolerance induction to self antigen", "Toll like receptor 2 signaling pathway", "Toll like receptor 3 signaling pathway", "Toll like receptor 4 signaling pathway", "Toll like receptor 7 signaling pathway", "Toll like receptor 8 signaling pathway", "Toll like receptor 9 signaling pathway", "Toll like receptor signaling pathway", "Tongue development", "Tongue morphogenesis", "Tooth mineralization", "Tor signaling", "Torc1 signaling", "Torc2 signaling", "Toxin metabolic process", "Toxin transport", "Trabecula formation", "Trabecula morphogenesis", "Trachea development", "Trachea formation", "Trachea morphogenesis", "Trail activated apoptotic signaling pathway", "Trans synaptic signaling by lipid", "Transcription by rna polymerase i", "Transcription by rna polymerase iii", "Transcription coupled nucleotide excision repair", "Transcription dependent tethering of rna polymerase ii gene dna at nuclear periphery", "Transcription elongation from rna polymerase i promoter", "Transcription elongation from rna polymerase ii promoter", "Transcription factor catabolic process", "Transcription initiation from rna polymerase i promoter", "Transcription initiation from rna polymerase ii promoter", "Transcription initiation from rna polymerase iii promoter", "Transcription preinitiation complex assembly", "Transcytosis", "Transepithelial chloride transport", "Transepithelial transport", "Transferrin transport", "Transforming growth factor beta activation", "Transforming growth factor beta production", "Transforming growth factor beta receptor signaling pathway", "Transforming growth factor beta1 production", "Transition between fast and slow fiber", "Transition metal ion homeostasis", "Transition metal ion transport", "Translational elongation", "Translational initiation", "Translational readthrough", "Translational termination", "Translesion synthesis", "Translocation of molecules into host", "Transmembrane receptor protein serine threonine kinase signaling pathway", "Transmembrane receptor protein tyrosine kinase signaling pathway", "Transmembrane receptor protein tyrosine phosphatase signaling pathway", "Transmembrane transport", "Transmission of nerve impulse", "Transport along microtubule", "Transport of virus", "Transposition", "Transposition rna mediated", "Tricarboxylic acid cycle", "Tricarboxylic acid metabolic process", "Trigeminal ganglion development", "Trigeminal nerve development", "Trigeminal nerve morphogenesis", "Triglyceride biosynthetic process", "Triglyceride catabolic process", "Triglyceride metabolic process", "Tripartite regional subdivision", "Tripeptide transmembrane transport", "Tripeptide transport", "Trivalent inorganic anion homeostasis", "Trna 3 end processing", "Trna 5 end processing", "Trna 5 leader removal", "Trna aminoacylation for mitochondrial protein translation", "Trna catabolic process", "Trna metabolic process", "Trna methylation", "Trna modification", "Trna processing", "Trna pseudouridine synthesis", "Trna thio modification", "Trna threonylcarbamoyladenosine metabolic process", "Trna transcription", "Trna transport", "Trna wobble base modification", "Trna wobble uridine modification", "Trophectodermal cell differentiation", "Trophoblast cell migration", "Trophoblast giant cell differentiation", "Tryptophan transport", "Tube development", "Tube formation", "Tube morphogenesis", "Tubulin complex assembly", "Tubulin deacetylation", "Tumor necrosis factor mediated signaling pathway", "Tumor necrosis factor superfamily cytokine production", "Type 2 immune response", "Type b pancreatic cell apoptotic process", "Type b pancreatic cell development", "Type b pancreatic cell proliferation", "Type i interferon production", "Type i pneumocyte differentiation", "Tyrosine catabolic process", "Tyrosine metabolic process", "Tyrosine phosphorylation of stat protein", "U4 snrna 3 end processing", "Ubiquinone metabolic process", "Ubiquitin dependent endocytosis", "Ubiquitin dependent erad pathway", "Ubiquitin dependent glycoprotein erad pathway", "Ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin dependent smad protein catabolic process", "Ubiquitin independent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin recycling", "Udp glucose metabolic process", "Udp n acetylglucosamine biosynthetic process", "Udp n acetylglucosamine metabolic process", "Ump biosynthetic process", "Unsaturated fatty acid biosynthetic process", "Unsaturated fatty acid metabolic process", "Urate metabolic process", "Urea cycle", "Urea metabolic process", "Ureter development", "Ureter morphogenesis", "Ureteric bud elongation", "Urogenital system development", "Uronic acid metabolic process", "Uterine smooth muscle contraction", "Uterus development", "Uterus morphogenesis", "Utp biosynthetic process", "Utp metabolic process", "Uv damage excision repair", "Uv protection", "V d j recombination", "Vacuolar acidification", "Vacuolar localization", "Vacuolar proton transporting v type atpase complex assembly", "Vacuolar transport", "Vacuole organization", "Vagina development", "Valine metabolic process", "Vascular associated smooth muscle cell apoptotic process", "Vascular associated smooth muscle cell differentiation", "Vascular associated smooth muscle cell migration", "Vascular associated smooth muscle cell proliferation", "Vascular associated smooth muscle contraction", "Vascular endothelial cell proliferation", "Vascular endothelial growth factor production", "Vascular endothelial growth factor receptor 2 signaling pathway", "Vascular endothelial growth factor receptor signaling pathway", "Vascular endothelial growth factor signaling pathway", "Vascular process in circulatory system", "Vascular transport", "Vascular wound healing", "Vasculature development", "Vasculogenesis", "Vasoconstriction", "Vasodilation", "Ventral spinal cord development", "Ventricular cardiac muscle cell action potential", "Ventricular cardiac muscle cell development", "Ventricular cardiac muscle cell differentiation", "Ventricular cardiac muscle cell membrane repolarization", "Ventricular cardiac muscle tissue development", "Ventricular cardiac muscle tissue morphogenesis", "Ventricular compact myocardium morphogenesis", "Ventricular septum development", "Ventricular septum morphogenesis", "Ventricular system development", "Ventricular trabecula myocardium morphogenesis", "Very long chain fatty acid catabolic process", "Very long chain fatty acid metabolic process", "Very low density lipoprotein particle assembly", "Very low density lipoprotein particle clearance", "Vesicle budding from membrane", "Vesicle cargo loading", "Vesicle cytoskeletal trafficking", "Vesicle docking", "Vesicle docking involved in exocytosis", "Vesicle fusion to plasma membrane", "Vesicle fusion with golgi apparatus", "Vesicle localization", "Vesicle mediated cholesterol transport", "Vesicle mediated transport", "Vesicle mediated transport between endosomal compartments", "Vesicle mediated transport in synapse", "Vesicle mediated transport to the plasma membrane", "Vesicle organization", "Vesicle targeting", "Vesicle targeting rough er to cis golgi", "Vesicle targeting to from or within golgi", "Vesicle tethering", "Vesicle tethering to golgi", "Vesicle transport along microtubule", "Vesicle uncoating", "Vestibulocochlear nerve development", "Vestibulocochlear nerve morphogenesis", "Viral budding", "Viral gene expression", "Viral genome replication", "Viral life cycle", "Viral process", "Viral protein processing", "Viral release from host cell", "Viral rna genome replication", "Viral transcription", "Viral translation", "Viral translational termination reinitiation", "Virion assembly", "Virion attachment to host cell", "Visual behavior", "Vitamin a metabolic process", "Vitamin b6 metabolic process", "Vitamin biosynthetic process", "Vitamin catabolic process", "Vitamin d metabolic process", "Vitamin d receptor signaling pathway", "Vitamin k metabolic process", "Vitamin metabolic process", "Vitamin transmembrane transport", "Vitamin transport", "Vocalization behavior", "Voluntary musculoskeletal movement", "Walking behavior", "Water homeostasis", "Water soluble vitamin biosynthetic process", "Water soluble vitamin metabolic process", "Water transport", "White fat cell differentiation", "Wnt protein secretion", "Wnt signaling pathway involved in heart development", "Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation", "Wound healing", "Wound healing involved in inflammatory response", "Wound healing spreading of epidermal cells", "Xenobiotic catabolic process", "Xenobiotic export", "Xenobiotic metabolic process", "Xenobiotic transmembrane transport", "Xenobiotic transport", "Xenobiotic transport across blood brain barrier", "Xenophagy", "Xmp metabolic process", "Zinc ion homeostasis", "Zinc ion transport", "Zygotic determination of anterior posterior axis embryo", "Zymogen activation", "Zymogen inhibition"], "available_proteins": ["AAAS", "AACS", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD6", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ADA", "ADAM17", "ADAM9", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT1S1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG2", "ALG5", "ALKBH5", "ALYREF", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APBB1", "APC", "APEH", "APEX1", "API5", "APLP2", "APOBEC3C", "APOL2", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID2", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARL8B", "ARMC1", "ARMC10", "ARMC6", "ARMC8", "ARMCX3", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARVCF", "ASAH1", "ASCC2", "ASCC3", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG4B", "ATG9A", "ATIC", "ATL2", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPAF2", "ATPIF1", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKB", "B4GAT1", "BABAM1", "BABAM2", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAP18", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BDH2", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD2", "BRD3", "BRD4", "BRD7", "BRD8", "BRIX1", "BSG", "BTF3", "BTRC", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C12orf73", "C19orf70", "C1D", "C1QBP", "C2CD2L", "C2CD5", "C3orf58", "C5orf51", "C8orf59", "CAB39", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALD1", "CALM3", "CALR", "CAMK1", "CAMK2G", "CAMLG", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN7", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CAST", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC22", "CCDC47", "CCDC6", "CCDC8", "CCDC93", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC20", "CDC23", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC6", "CDC73", "CDCA2", "CDCA5", "CDCA7L", "CDCA8", "CDH2", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDKN2AIP", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPV", "CEP135", "CEP250", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHP1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIRBP", "CISD1", "CISD2", "CIZ1", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSTN3", "CLTA", "CLTC", "CLU", "CLUH", "CMAS", "CMPK1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT10", "CNOT11", "CNOT2", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COG3", "COG7", "COIL", "COLEC12", "COLGALT1", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "COQ8B", "COQ9", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CREB1", "CREG1", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CRYZL1", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTH", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CUTA", "CWC15", "CWC22", "CWF19L1", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCD", "DCP1A", "DCP2", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTPP1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DECR1", "DEK", "DENND4C", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS4", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB4", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPM1", "DPP3", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS3L", "DUSP12", "DUSP3", "DUT", "DVL2", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFHD1", "EFL1", "EFTUD2", "EGFR", "EHD1", "EHD4", "EHHADH", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENPP1", "ENSA", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPDR1", "EPHA7", "EPHX1", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EYA4", "EZH2", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAH", "FAM120B", "FAM129B", "FAM162A", "FAM208A", "FAM210B", "FAM213A", "FAM3C", "FAM49B", "FAM8A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD5", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNBP1L", "FNDC3A", "FOXK1", "FOXK2", "FOXRED1", "FSCN1", "FSTL1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GGH", "GGPS1", "GHITM", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLO1", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPB", "GMPS", "GNA13", "GNAI2", "GNAI3", "GNB1L", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA4", "GOLGA5", "GOLGB1", "GOLPH3", "GOLPH3L", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPD2", "GPHN", "GPI", "GPKOW", "GPR107", "GPR108", "GPR89B", "GPS1", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS4", "HAUS5", "HAUS6", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HINT2", "HIRA", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN3", "HMGXB4", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOOK2", "HOXD13", "HP1BP3", "HPRT1", "HPS6", "HPSE", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBIP", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPAD1", "IMPDH2", "INA", "INCENP", "INF2", "INTS1", "INTS11", "INTS12", "INTS13", "INTS14", "INTS3", "INTS4", "INTS7", "INTS9", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRS4", "ISCU", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITM2B", "ITM2C", "ITPA", "ITPRIP", "IVD", "IWS1", "JAGN1", "JMJD6", "JUP", "KARS", "KAT7", "KCTD12", "KCTD5", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0368", "KIAA0391", "KIAA1468", "KIF11", "KIF14", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAMTOR3", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LPGAT1", "LRBA", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRRC40", "LRRC47", "LRRC59", "LRRC8C", "LRRFIP2", "LRSAM1", "LRWD1", "LSG1", "LSM14B", "LSM2", "LSM3", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L", "LUC7L2", "LUC7L3", "LUZP1", "LYAR", "LYN", "LYPLA1", "LZTFL1", "LZTS2", "MACF1", "MAD2L1", "MAGED1", "MAGED2", "MAGT1", "MAK16", "MAN1A1", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K4", "MAP4", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARCKSL1", "MARK2", "MARK3", "MARS", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBOAT7", "MCAM", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MEAF6", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED21", "MED23", "MED24", "MED25", "MED4", "MEN1", "MEPCE", "MESD", "METAP1", "METTL13", "METTL15", "MFAP1", "MFF", "MFN1", "MFSD10", "MFSD3", "MFSD5", "MGEA5", "MGME1", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MIF", "MINDY3", "MINPP1", "MIOS", "MIPEP", "MKI67", "MKRN2", "MLEC", "MMAB", "MMS19", "MMS22L", "MOGS", "MON2", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPDZ", "MPG", "MPHOSPH10", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRC2", "MRE11", "MRGBP", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL19", "MRPL2", "MRPL20", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL43", "MRPL44", "MRPL47", "MRPL55", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS27", "MRPS28", "MRPS30", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTM1", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MTX3", "MUT", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO6", "NAA10", "NAA15", "NAA40", "NAA50", "NACC1", "NADK2", "NAE1", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCBP1", "NCBP3", "NCDN", "NCK1", "NCK2", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "NDC1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFC2", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NEU1", "NF2", "NFRKB", "NFS1", "NFU1", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NISCH", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NME3", "NME7", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NRBP1", "NRDC", "NRP1", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDT1", "NUDT12", "NUDT16L1", "NUDT21", "NUDT5", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "ORC5", "OS9", "OSBP", "OSBPL11", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD7B", "OXA1L", "OXSR1", "P3H1", "P3H3", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1IP1", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PAOX", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATJ", "PAWR", "PAXBP1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH19", "PCID2", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE4DIP", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDP1", "PDS5A", "PDS5B", "PDSS2", "PDXK", "PDZD11", "PEBP1", "PECR", "PEF1", "PELP1", "PEPD", "PES1", "PEX14", "PEX16", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHRF1", "PI4K2A", "PI4KA", "PI4KB", "PIBF1", "PICALM", "PIGK", "PIGL", "PIGS", "PIGT", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PKP2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNN", "PNP", "PNPLA6", "PNPO", "PNPT1", "POFUT1", "POFUT2", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2D", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3F", "POLRMT", "POMGNT2", "PON2", "POP1", "POP4", "POR", "PPA2", "PPAN", "PPAT", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP1R9B", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PRAF2", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "PYM1", "QARS", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABEP1", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBFOX2", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM39", "RBM4", "RBM42", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "RECQL5", "REEP3", "REEP4", "REEP5", "REL", "REPS1", "RER1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RICTOR", "RIDA", "RIF1", "RILPL1", "RINT1", "RIOX1", "RIOX2", "RMDN1", "RMDN3", "RNASEH2A", "RNASET2", "RNF114", "RNF14", "RNF20", "RNF219", "RNF40", "RNH1", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSU1", "RTCA", "RTCB", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "RXRB", "S100A10", "S100A11", "S100A13", "SAAL1", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SASS6", "SATB2", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDCCAG3", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT8", "SEPT9", "SERAC1", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHC1", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIN3A", "SIN3B", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC30A7", "SLC35A4", "SLC35B2", "SLC35F2", "SLC38A2", "SLC3A2", "SLC4A7", "SLC5A6", "SLC6A15", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLMAP", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG8", "SMG9", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SNAP23", "SNAP29", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG5", "SPAG9", "SPART", "SPATA5", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPECC1", "SPECC1L", "SPEN", "SPNS1", "SPOUT1", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRBD1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD3NL", "STAT1", "STAU1", "STAU2", "STIP1", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX3", "STX5", "STX6", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACO1", "TAF15", "TAF4", "TAF7", "TAGLN2", "TALDO1", "TAMM41", "TAOK3", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCF25", "TCOF1", "TCP1", "TDP2", "TDRKH", "TECR", "TELO2", "TENM3", "TERF2IP", "TES", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THADA", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM13", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TIMM9", "TJP1", "TJP2", "TK1", "TKT", "TLN1", "TM9SF2", "TM9SF3", "TM9SF4", "TMCO1", "TMED1", "TMED10", "TMED2", "TMED5", "TMED9", "TMEM109", "TMEM11", "TMEM126A", "TMEM14C", "TMEM165", "TMEM167A", "TMEM199", "TMEM201", "TMEM214", "TMEM30A", "TMEM33", "TMEM38B", "TMEM43", "TMEM59", "TMEM70", "TMEM97", "TMF1", "TMLHE", "TMOD1", "TMOD3", "TMTC3", "TMX1", "TMX2", "TMX3", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOM1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOPBP1", "TOR1A", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TP53", "TP53BP1", "TP53BP2", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRIT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN6", "TSPO", "TSPYL1", "TSR1", "TSR2", "TST", "TSTA3", "TTC1", "TTC19", "TTC21B", "TTC26", "TTC37", "TTC4", "TTC5", "TTF2", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UACA", "UAP1", "UBA1", "UBA2", "UBA5", "UBA6", "UBAC1", "UBAP2L", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBL5", "UBLCP1", "UBN2", "UBP1", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "UMPS", "UNC119B", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "URB2", "UROD", "USE1", "USO1", "USP1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP28", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "UXS1", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VASP", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VPS13A", "VPS18", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS51", "VPS52", "VPS53", "VRK1", "VRK2", "VTA1", "WAPL", "WARS", "WARS2", "WASF2", "WASHC4", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR36", "WDR41", "WDR43", "WDR45B", "WDR46", "WDR5", "WDR6", "WDR61", "WDR73", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIZ", "WLS", "WNK1", "WNK3", "WRAP53", "WRAP73", "WTAP", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YBX1", "YEATS2", "YEATS4", "YES1", "YIF1A", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZFYVE16", "ZMPSTE24", "ZMYM3", "ZMYM4", "ZMYND8", "ZNF207", "ZNF281", "ZNF318", "ZNF326", "ZNF512B", "ZNF598", "ZNF622", "ZNF638", "ZPR1", "ZRANB2", "ZW10", "ZYX", "ZZEF1"], "leading_proteins": ["ABAT", "ABHD10", "ABHD12", "ACAA1", "ACLY", "ACOT8", "ACOX1", "ACOX3", "ACP6", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ADA", "ADAM17", "ADAR", "ADD1", "ADD2", "ADD3", "ADI1", "ADPGK", "AFDN", "AFG3L2", "AGK", "AGPS", "AHCYL1", "AIFM1", "AIP", "AKAP1", "AKAP9", "AKT1", "AKT2", "ALCAM", "ALDH1A2", "ALDH1B1", "ALDH3A2", "ALG1", "ALG11", "AMOT", "AMPD2", "ANAPC5", "ANKLE2", "ANO6", "AP1G1", "AP1M1", "AP2B1", "AP2S1", "AP3D1", "AP3M1", "AP3S1", "APC", "APEH", "APOL2", "APP", "ARCN1", "ARFIP2", "ARHGEF2", "ARIH1", "ARL6IP5", "ARMC1", "ARMC10", "ARMC8", "ARPC2", "ARVCF", "ASCC2", "ASNA1", "ATAD1", "ATAD3A", "ATAD3B", "ATG4B", "ATL2", "ATP13A1", "ATP1A1", "ATP1B1", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5B", "ATP5F1", "ATP5L", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1B2", "ATP6V1D", "ATP6V1H", "ATPIF1", "ATXN10", "BAG4", "BAG6", "BAIAP2", "BAX", "BCAP31", "BCAS3", "BCL2L13", "BCOR", "BICD2", "BNIP1", "BSG", "BTRC", "BYSL", "C12orf73", "C1QBP", "C2CD5", "C3orf58", "CAD", "CADM1", "CALCOCO1", "CALD1", "CALM3", "CALR", "CAMK1", "CAMK2G", "CAMLG", "CANT1", "CANX", "CAPZA1", "CARM1", "CASK", "CCAR2", "CCDC22", "CCDC47", "CCDC93", "CCNA2", "CCT2", "CCT3", "CCT4", "CD2AP", "CDC34", "CDC37", "CDC42", "CDC45", "CDK1", "CDK4", "CDK5", "CDK5RAP3", "CDK9", "CDKN2AIP", "CEP135", "CEP250", "CERS2", "CETN2", "CFDP1", "CHAC2", "CHCHD3", "CHID1", "CHKA", "CHMP2A", "CHMP5", "CHMP7", "CHORDC1", "CHST14", "CHUK", "CIRBP", "CLCC1", "CLCN3", "CLIC1", "CLNS1A", "CLPB", "CLPTM1", "CLSTN3", "CLTA", "CLTC", "CLU", "CLUH", "CNNM4", "CNOT11", "CNOT2", "CNOT7", "CNPY2", "COA3", "COMT", "COPB2", "COPG1", "COPS2", "COPS4", "COPS5", "COPS8", "COQ8A", "COQ9", "COX18", "COX2", "COX4I1", "COX7A2", "CPPED1", "CREB1", "CRTAP", "CSNK2B", "CTCF", "CTH", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CWC22", "CYB5B", "CYB5D2", "CYFIP1", "CYP51A1", "DAGLB", "DCP1A", "DCP2", "DCTN1", "DCTN2", "DCTPP1", "DCUN1D4", "DCUN1D5", "DDA1", "DDRGK1", "DDX3X", "DENND4C", "DHCR24", "DHFR", "DHPS", "DHX29", "DHX33", "DHX36", "DHX8", "DIABLO", "DIAPH3", "DICER1", "DLG1", "DNAJA1", "DNAJA2", "DNAJC1", "DNAJC13", "DNAJC2", "DNAJC7", "DNM1L", "DNM2", "DOHH", "DOLPP1", "DVL2", "DYM", "DYNC2H1", "EBP", "ECD", "ECE1", "ECSIT", "EDC3", "EDC4", "EEA1", "EEF1D", "EGFR", "EHD4", "EI24", "EIF2AK2", "EIF2B2", "EIF2D", "EIF2S1", "EIF3E", "EIF3H", "EIF4B", "EIF4G1", "EIF4H", "EIF5", "ELP1", "ELP3", "EMC7", "EMD", "ENPP1", "ENSA", "EPHA7", "EPHX1", "EPS15", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERGIC3", "ERLIN2", "ETNK1", "EXO1", "EXOC4", "EXOC6", "EXOG", "EXOSC2", "EXOSC6", "EYA4", "EZR", "FADS2", "FAF1", "FAH", "FAM129B", "FAM162A", "FAM49B", "FANCD2", "FASN", "FECH", "FERMT2", "FGFR1OP", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP4", "FKBP7", "FKBP9", "FKRP", "FLII", "FLOT1", "FLOT2", "FMR1", "FNBP1L", "FOXRED1", "FUS", "FXR2", "G3BP2", "G6PD", "GAK", "GALNT1", "GALNT2", "GALNT7", "GAPVD1", "GART", "GBF1", "GCC2", "GDAP1", "GET4", "GGA2", "GGCX", "GGPS1", "GINS4", "GLG1", "GLMN", "GOLGA2", "GOLGA4", "GOLGA5", "GOLPH3", "GOLPH3L", "GOPC", "GOSR1", "GPAA1", "GPAM", "GPD2", "GPHN", "GPR107", "GPR108", "GPR89B", "GRB2", "GRIPAP1", "GSK3B", "GSTO1", "GTF2B", "GTF2F1", "GTPBP1", "GTPBP3", "HACD3", "HADH", "HAUS4", "HAUS5", "HAUS6", "HDAC2", "HDDC2", "HDGF", "HDGFL2", "HECTD1", "HGS", "HK2", "HM13", "HMGB1", "HMGB2", "HMOX1", "HMOX2", "HNRNPA2B1", "HNRNPAB", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HOOK2", "HPRT1", "HPS6", "HPSE", "HS2ST1", "HSD17B11", "HSP90AA1", "HSP90AB1", "HSPA8", "HTRA2", "HTT", "ICMT", "IGBP1", "IGF2BP1", "IGF2BP2", "IKBIP", "ILK", "IMPAD1", "IPO4", "IPO5", "IPO9", "IRS4", "IST1", "ITCH", "ITGB1", "ITM2B", "KAT7", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM5A", "KDSR", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIF14", "KIF1B", "KIF5B", "KIF7", "KIFBP", "KLC2", "KMT2A", "KTN1", "LAMB1", "LARS", "LBR", "LDAH", "LEMD2", "LETM1", "LLGL1", "LMAN1", "LMNA", "LNPEP", "LONP1", "LPCAT1", "LRBA", "LRP2", "LRPAP1", "LRPPRC", "LRRC8C", "LRSAM1", "LSS", "LTV1", "LUZP1", "MACF1", "MAD2L1", "MAGED1", "MAN1A1", "MAN1A2", "MAP1A", "MAP2K1", "MAPK1", "MAPK14", "MAPK3", "MAPRE2", "MATR3", "MBOAT7", "MCL1", "MCM2", "MCM3", "MCM4", "MCM7", "MCU", "MCUB", "ME1", "MED1", "MED12", "MED21", "MED25", "MESD", "MFF", "MFN1", "MGEA5", "MGME1", "MIA2", "MIA3", "MICU1", "MICU2", "MIF", "MKRN2", "MOSPD2", "MPC2", "MPP1", "MPP2", "MPP5", "MPV17L2", "MRC2", "MSH2", "MSMO1", "MSN", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFS", "MTMR2", "MTOR", "MTR", "MTX1", "MTX3", "MYCBP", "MYH10", "MYH14", "MYH9", "MYL6", "MYO1C", "NAA10", "NAA15", "NAA40", "NAA50", "NAE1", "NAGLU", "NAMPT", "NAP1L1", "NAPA", "NCAPG", "NCKIPSD", "NCLN", "ND1", "NDC1", "NDUFA11", "NDUFA4", "NDUFA6", "NDUFAF2", "NDUFAF7", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFS2", "NEFL", "NEK9", "NENF", "NES", "NF2", "NIPBL", "NISCH", "NLN", "NMD3", "NME3", "NNT", "NOM1", "NONO", "NOVA2", "NPEPPS", "NSD2", "NSFL1C", "NSUN2", "NSUN5", "NT5C3B", "NTHL1", "NTMT1", "NUB1", "NUCB2", "NUCKS1", "NUDC", "NUDT12", "NUF2", "NUP37", "NUP62", "NUP88", "NUP93", "OCIAD1", "OCLN", "OGT", "OPA1", "OPA3", "ORC3", "OS9", "OSBP", "OSBPL11", "OXSR1", "P3H1", "P3H3", "P3H4", "P4HA1", "P4HA2", "P4HB", "PACSIN2", "PAIP1", "PAIP2", "PAK2", "PAOX", "PARP1", "PARP2", "PBK", "PCBD1", "PCID2", "PCM1", "PCYOX1", "PDCD4", "PDCD5", "PDCL3", "PDE12", "PDE4DIP", "PDP1", "PELP1", "PEX14", "PEX16", "PEX19", "PEX5", "PFDN2", "PFDN6", "PGAM1", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF8", "PIBF1", "PIGK", "PIGS", "PIH1D1", "PIK3C2A", "PIN4", "PIP4K2C", "PIR", "PISD", "PITRM1", "PLA2G15", "PLD6", "PLIN3", "PLOD3", "PLXNB2", "PMPCA", "POFUT1", "POFUT2", "POLDIP2", "POLR3C", "POR", "PPAT", "PPHLN1", "PPM1F", "PPP1R9B", "PPP2R1A", "PPP2R1B", "PPP3CA", "PPP4R3A", "PPT1", "PRCP", "PRELID1", "PREPL", "PRKAA1", "PRKRA", "PRMT3", "PRMT5", "PRMT9", "PRPSAP1", "PSAP", "PSMA2", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC3", "PSMD11", "PSMD2", "PSMD7", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG1", "PSPC1", "PTBP2", "PTDSS1", "PTDSS2", "PTK7", "PTPN1", "PTPN23", "PTPRF", "PUF60", "PURA", "PUS7", "PXMP2", "PYGL", "PYM1", "QKI", "RAB10", "RAB11B", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB34", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RABEP1", "RABGAP1", "RAC1", "RAD50", "RANBP1", "RANBP2", "RAPGEF2", "RAVER1", "RBFOX2", "RBM10", "RBM15", "RBM3", "RBM4", "RBMX", "RBPJ", "RCN1", "RDH13", "RDX", "REEP3", "REEP4", "REL", "REPS1", "RETSAT", "REXO2", "RHEB", "RHOA", "RIC8A", "RIOX1", "RMDN1", "RMDN3", "RNF114", "RNF14", "RNF20", "RNF40", "RNPS1", "ROCK1", "ROCK2", "RPL24", "RPL3", "RPS3", "RPS6KA1", "RPS6KA3", "RRM2", "RTN2", "RTN3", "RTN4", "RTN4IP1", "S100A10", "S100A13", "SAMD4B", "SAMHD1", "SAR1A", "SAR1B", "SCAMP1", "SCARB1", "SCO1", "SDCCAG3", "SDF4", "SEC11A", "SEC16A", "SEC23B", "SEC24B", "SEL1L", "SEPT2", "SEPT6", "SET", "SETDB1", "SFPQ", "SFXN4", "SGPL1", "SH3GLB1", "SIGMAR1", "SIRT1", "SIRT2", "SKP1", "SLC12A2", "SLC19A1", "SLC1A5", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A26", "SLC25A32", "SLC25A33", "SLC30A7", "SLC35B2", "SLC35F2", "SLC38A2", "SLC4A7", "SLC7A1", "SLIT2", "SLMAP", "SMC2", "SMC3", "SMC4", "SMG9", "SNAP29", "SNX12", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SPAG9", "SPART", "SPATA5", "SPC24", "SPCS2", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQSTM1", "SRM", "SRP68", "SRPRB", "SRRT", "SRSF1", "SRSF3", "SRSF6", "SRSF7", "SSNA1", "SSR1", "STARD3", "STARD3NL", "STAT1", "STAU1", "STK4", "STMN1", "STRN", "STX12", "STX18", "STX3", "STX5", "STX6", "STXBP4", "SUN1", "SUN2", "SURF4", "SV2A", "SYAP1", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "TACO1", "TAF15", "TAF4", "TAF7", "TAOK3", "TAP1", "TDRKH", "TECR", "TELO2", "TENM3", "TERF2IP", "TEX264", "TFIP11", "THADA", "THOP1", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM13", "TIMM17A", "TIMM17B", "TIMM23", "TIMM8A", "TIMM8B", "TIMM9", "TJP1", "TJP2", "TM9SF2", "TM9SF3", "TM9SF4", "TMED10", "TMED2", "TMED5", 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0.0067516864730134 7.157766990291262 15.730582524271844 1.3245491566248977 0.2112996285983387 3.5767402396348245 0.8689557679680192 1.477430451036954 0.2853006280851536 8.959341197176402e-05 0.0001122733832082 3.4550328168080166e-05 0.0012174977382918 0.0002808101441202 +Endoplasmic reticulum golgi intermediate compartment membrane 13 27 2.6540349021520067 0.0079535599744429 10.49271844660194 25.839805825242717 1.5441023898993702 0.2324243418613106 5.505729177420246 3.7718384126099376 1.49831312620529 0.2965572765953523 0.0297291996339351 0.0285808600856777 0.0157478410048603 0.0443488880214379 0.0002790542910114 +Proton transporting two sector atpase complex proton transporting domain 3 10 2.549592120164308 0.0107849014185239 4.053398058252427 10.283980582524272 1.020958321179617 0.2307004649223604 1.8491832641634656 1.1862626633334956 1.3576055733210162 0.273185751006507 2.646974215992049e-05 4.557535944516599e-05 1.0100053103379697e-05 0.0003774704498572 0.0049531384619904 +Tim23 mitochondrial import inner membrane translocase complex 2 6 2.4821084127373263 0.0130607531988937 2.2694174757281553 6.342233009708738 1.5180442383336388 0.125307709046494 1.369833329272529 0.8106469094037756 1.2674744491900518 0.2021471972412396 0.0076283220326718 0.0012105019492812 0.0047533286028597 0.0280420066437826 0.0141665154869097 +Copi coated vesicle 5 14 2.4783558767613982 0.0131989423040934 3.366504854368932 13.565533980582524 0.927757948703832 0.3021632050419245 1.9356503178232003 1.3008870969982682 1.2180478421179144 0.2957691490409697 0.0017607202845482 0.0919337377678228 0.0008717411361388 0.0012174977382918 0.0002808101441202 +Copi coated vesicle membrane 3 13 2.4528500057677003 0.0141729423241601 2.9611650485436893 12.451456310679612 0.9351146201256926 0.2894293018559171 1.7580457491925867 1.2208038158644114 1.2401568068418547 0.2855671555488221 0.0008964292433366 0.0742352733278267 0.000440337804097 0.000493734331549 0.0007525839576665 +Cytochrome complex 5 17 2.4220274067717016 0.0154341864721754 6.021844660194175 16.08495145631068 1.0267019648816196 0.2321293206617183 2.9315837025395948 1.6175814223208935 1.624269406530766 0.2919563386676546 0.0488111156132814 0.1305522111527444 0.031373049189738 0.0050285619271962 0.002368909886278 +Proton transporting two sector atpase complex 4 23 2.4031638280671705 0.0162539038340185 7.116504854368932 22.25728155339806 1.0735578367707936 0.2848832687688338 3.2910616544032156 1.9833825153714253 1.32099194967518 0.2987458873835026 5.348929749667124e-05 0.0005621116792476 1.6515245584177265e-05 0.0012777259352904 0.0010690688695759 +Proteasome core complex beta subunit complex 5 7 2.3837050511536773 0.0171393330701299 3.699029126213592 6.970873786407767 1.6670727234653664 0.1509307531330224 1.4503762582219135 0.1681602725795027 0.9611878160538336 0.233503072382129 0.1051177798435183 0.0424464003246627 0.0832836732680532 0.0010713621736615 9.6474859037805e-07 +Lipid droplet 3 31 2.366240825356534 0.0179697510939791 7.313106796116505 30.72087378640777 0.9597061621709796 0.3916106255858687 3.663189105886808 2.181620314734523 1.1934081113966928 0.3497541884861006 0.0086417543300216 0.0399341953324298 0.0036673828223822 0.0765288163518146 0.4025970872086286 +Ciliary basal body 13 26 2.333876699264178 0.0196021791531921 5.252427184466019 18.766990291262136 0.3291521736423572 0.5817838581641566 2.9698107115056382 4.463887207345828 0.8023105632951456 0.3105252801373722 0.4343828281714748 0.4409382257745535 0.3210427924142759 0.1680099051588612 0.1310204831429489 +Calcium channel complex 4 9 2.2421163989251984 0.0249538504004573 2.4150485436893203 7.298543689320389 0.1538765288718164 0.4525613292140901 1.4615016707365889 1.3130036030733032 1.08449347730351 0.3081575616966512 1.0 1.0 1.0 0.0175758241055335 0.0043704316922178 +Endoplasmic reticulum golgi intermediate compartment 19 53 2.207556066325223 0.0272752345850051 14.888349514563108 49.49271844660194 1.4759277407874345 0.3201471070907981 6.47003250199477 5.053350843348441 1.420924643396655 0.3585240832471577 0.0070044874990744 0.0115248505448644 0.0024838215389039 0.0320816058630516 7.314918023846158e-05 +Golgi stack 18 36 2.199958571675814 0.0278098344668136 9.67233009708738 31.25242718446602 0.7055900861920908 0.4265468940333196 4.557817503574521 5.847941213698429 1.2226912303929196 0.3463938041520717 0.3386746096859705 0.377722993581858 0.2426635790855314 0.2156193562785021 0.0028040551110462 +Respiratory chain complex iv 3 11 2.109871119159901 0.0348694585148299 3.754854368932039 9.74271844660194 0.8119042784517004 0.2590637228606872 2.032646352020888 1.0643473720992946 1.3870085883810457 0.2875864020654643 0.1992649039447594 1.0 0.1596960736798767 0.0698282842903305 0.0098879726868235 +Intrinsic component of golgi membrane 6 10 2.0565305568937684 0.0397314040418963 4.655339805825243 10.08495145631068 1.3178763872097854 0.2129685736028588 2.6046347098798024 1.9780511021437377 1.2704958978874823 0.2699640456705705 0.4049686248457887 0.1835089509173778 0.3339976348230559 0.6452412597701435 0.1466332856037892 +Golgi associated vesicle membrane 6 21 2.028591950327425 0.0424998691389333 4.201456310679611 19.589805825242717 0.79417597045559 0.3511132904952779 2.457541951272857 2.384047500904294 1.2111660039755976 0.3110721945776767 0.0127748373260935 0.1755724648168266 0.0065760397653667 0.0157211013123339 0.0435237537141962 +Proton transporting v type atpase complex 2 11 2.020832196603079 0.0432971386746547 3.1723300970873787 11.17233009708738 1.083137374920517 0.3054753623634815 1.8106779848505148 1.1913569842207026 0.9186852151104662 0.2868810804648729 0.0010788177062325 0.0786913117950012 0.0005309775927247 0.0075105395483816 0.0470360579614364 +Proteasome core complex 5 15 2.005059390997417 0.0449566981509563 5.325242718446602 14.563106796116504 1.2215341624098188 0.3078540255827756 2.4387733048296822 0.5516067072365743 1.1166106206832802 0.3218631020970666 0.1893094745604938 0.0786913117950012 0.1515272625734178 0.0075105395483816 0.0001016217979366 +Myofilament 2 5 1.974367881463132 0.0483399273929991 2.174757281553398 4.186893203883495 0.404875148061941 0.4374833583964219 1.241883821669583 1.0388207738802084 1.088024284468753 0.3207832055944606 0.1160984687124442 1.0 0.0921025797166938 0.0233125205204954 0.010684483318579 +Striated muscle thin filament 2 5 1.974367881463132 0.0483399273929991 2.0776699029126213 4.036407766990291 0.3903791791430543 0.4433177448944362 1.1590866875641097 0.8708520037106524 1.0789606331951869 0.3204744543463996 0.1051177798435183 1.0 0.0832836732680532 0.0189506401306209 0.0077568745967145 +Intrinsic component of endoplasmic reticulum membrane 15 56 1.9743024334163937 0.0483473643788505 21.439320388349515 53.03155339805825 1.5445183869163015 0.2945609219212759 9.936629672422429 6.151523176643304 2.1054078800196185 0.3580268322643601 0.2009904109819738 0.4570575797650001 0.1209939299005533 0.033999428209828 0.0032505893605234 +Cilium 29 92 1.9634046232710367 0.0495991770498924 19.73543689320388 86.1383495145631 0.118410348573801 0.7444368007832043 7.660604462537825 10.50879359902771 0.6228634571259211 0.295699066268612 0.6289479258297694 0.5069131365490065 0.4376716612181645 0.4841942172064835 0.3513742919578417 diff --git a/msigdb_gocc/metrics.json b/msigdb_gocc/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..ccf6c0139f3a7e4be957da708a4d11b596e11611 --- /dev/null +++ b/msigdb_gocc/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3381, + "annotations_size": 911, + "title": "Average number of proteins per term", + "value": 30.6827661909989 +} \ No newline at end of file diff --git a/msigdb_gocc/paths.json b/msigdb_gocc/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..f3e8b355bc44882d47bef691b6db4e21b18d670f --- /dev/null +++ b/msigdb_gocc/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gocc/fragment/C317/C317_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gocc/result.tsv b/msigdb_gocc/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..65f9f6bee8c1fcc0e215e322657425a5e5fceab0 --- /dev/null +++ b/msigdb_gocc/result.tsv @@ -0,0 +1,307 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Intrinsic component of organelle membrane 0.5417211369036428 3.709216154883396 0.0002079018841107 0.1725596900460294 0.1012228893331143 140 O95563,O60830,Q9Y287,P57105,Q9Y4W6,Q13505,Q8N8Q8,Q9Y282,Q15388,Q9NQC3,Q9NPA0,O43808,Q99595,P42892,Q96A33,Q12981,O95470,Q9BPX6,O14925,Q15125,O94901,Q8TCT9,O43752,Q8TB36,Q53H12,O95070,Q14739,Q86YN1,P98194,O15126,Q9Y5Y5,Q03518,Q86XL3,Q8TB61,Q6ZRP7,Q5HYI7,Q53S58,Q9UH99,Q9NX63,Q86UP2,Q15629,Q5T9L3,O75880,O75298,Q9Y2R0,Q9NWR8,P17152,Q9GZY8,O43292,O75844,P49069,Q9UG56,Q10471,Q8IWA4,Q6P4A7 55 +Inner mitochondrial membrane protein complex 0.5625144412759988 3.692313050396941 0.0002222236867905 0.1832876085293428 0.1012228893331143 81 O60830,Q9Y5J7,Q13505,Q9Y4W6,P22695,P03886,Q99595,O14949,Q86Y39,Q9BPX6,P00846,O14925,O75964,Q9UDW1,P56556,Q8IYU8,P56378,O43676,P14406,P00403,Q5HYI7,Q9NX63,O96000,P13073,Q9NWR8 25 +Outer membrane 0.4786442733676309 3.3001280099949737 0.0009664073658222 0.5855582295378212 0.2153029722382429 95 P57105,Q13505,Q9NS69,Q8WWV3,O60313,Q6NUM9,Q8WXH0,P42704,Q9UKU0,Q8N4H5,P30536,O00429,Q8WY22,Q9Y6C9,P21796,P09601,Q9HCL2,Q5HYI7,O43169,Q9NX63,P45880,Q99720,Q8IWA4,Q9GZY8,P50402,Q8N2A8 26 +Intrinsic component of mitochondrial membrane 0.6665789368680896 3.255630089257655 0.0011314105202477 0.6434563139105265 0.2153029722382429 50 O60830,O95563,P57105,Q9Y4W6,Q13505,Q8N8Q8,Q99595,Q9BPX6,O14925,Q53S58,Q5HYI7,Q9NX63,O75880,Q9Y2R0,Q6P4A7,P17152,Q9NWR8,Q9GZY8,Q8IWA4,Q9UG56 20 +Intrinsic component of mitochondrial inner membrane 0.7049629017374487 3.2432644361079164 0.0011816848092109 0.6594357279466435 0.2153029722382429 34 O75880,O14925,Q9Y2R0,O60830,O95563,Q9Y4W6,Q13505,P17152,Q9NWR8,Q8N8Q8,Q53S58,Q5HYI7,Q99595,Q9NX63,Q9UG56,Q6P4A7 16 +Golgi cisterna membrane 0.6991399622904512 3.1094488136348346 0.0018743675843291 0.8189806158950503 0.2247363751006369 20 O00461,Q8WVQ1,Q9H4A5,P0CG08,Q10472,Q08379,Q9H4A6,Q15363,Q10713,Q8NBZ7 10 +Golgi membrane 0.4891694443777212 3.041982864622911 0.002350252732084 0.8827679796469108 0.2247363751006369 143 Q9H4A5,Q9Y287,O95197,Q9Y282,Q13439,Q8TBA6,Q13190,Q10713,Q16739,Q9HD26,P24390,O95249,O00461,P0CG08,O43752,O60476,Q9HC07,Q08379,O95721,Q8NDZ4,Q15392,Q9H4A6,Q15363,P33908,O95070,Q96S66,Q8TB61,Q8NCH0,O43731,Q6ZRP7,Q9P2W9,P49755,Q5T9L3,Q10472,Q8IUD2,Q9H9S5,Q7LGA3,O15027,Q92896,O15260 40 +Golgi cisterna 0.6602102624780998 2.872519145547494 0.0040721340394092 0.9757002181113184 0.2853626238385988 27 O95249,O00461,Q8WVQ1,Q9H4A5,P0CG08,Q10472,Q08379,Q9BZG1,Q9H4A6,Q8TBA6,Q15363,Q10713,Q8NBZ7 13 +Cis golgi network 0.7083689562430686 2.7698804708166365 0.0056076867513286 0.9940417599012934 0.3237255987850155 17 O95249,O00461,Q9NPR9,Q08379,P30533,O43731,Q8TBA6,Q99996,P49755,P24390 10 +Golgi apparatus subcompartment 0.4339755407630298 2.721553707896852 0.006497582588679 0.9973643145836568 0.3237255987850155 96 Q9H4A5,Q9NX62,Q13439,Q96ED9,Q9BZG1,Q8TBA6,Q10713,O95249,O00461,P0CG08,O43752,Q9HC07,Q08379,Q9H4A6,Q15363,Q8NBZ7,P53365,Q9BWS9,Q9UJY4,Q99996,Q5T9L3,Q9NPR9,Q8WVQ1,Q10472,Q4J6C6,Q9UID3 26 +Outer mitochondrial membrane protein complex 0.715777489703967 2.708849961986246 0.0067516864730134 0.9979122000127504 0.3237255987850155 16 Q8N4H5,Q13505,Q9NS69,Q5HYI7,Q9NX63 5 +Endoplasmic reticulum golgi intermediate compartment membrane 0.6290702539144211 2.6540349021520067 0.0079535599744429 0.999307125288626 0.3497392803057181 27 Q03518,Q10472,Q9BVK6,Q08379,Q9Y282,Q15363,Q8N511,P49257,Q13190,O95070,P49755,O15260,P24390 13 +Proton transporting two sector atpase complex proton transporting domain 0.7979833374557493 2.549592120164308 0.0107849014185239 0.9999487302835476 0.4238844614075475 10 P00846,O75964,Q93050 3 +Tim23 mitochondrial import inner membrane translocase complex 0.8791627451515792 2.4821084127373263 0.0130607531988937 0.9999937111359248 0.4453420903344128 6 Q99595,O60830 2 +Copi coated vesicle 0.7059162908301239 2.4783558767613982 0.0131989423040934 0.9999944643152252 0.4453420903344128 14 O43731,Q8NDZ4,Q15363,Q8N511,P24390 5 +Copi coated vesicle membrane 0.7141478232746391 2.4528500057677003 0.0141729423241601 0.9999977485173576 0.4611268020467807 13 Q8N511,O43731,P24390 3 +Cytochrome complex 0.6515723576607964 2.4220274067717016 0.0154341864721754 0.999999298594714 0.4848463405569591 17 Q9UDW1,P22695,P00403,O14949,P14406 5 +Proton transporting two sector atpase complex 0.5950873087235531 2.4031638280671705 0.0162539038340185 0.9999996715774327 0.48982819903545 23 P00846,O75964,Q9Y487,Q93050 4 +Proteasome core complex beta subunit complex 0.8341973934608833 2.3837050511536773 0.0171393330701299 0.9999998553989762 0.48982819903545 7 P28072,P28070,P28074,P20618,P49721 5 +Lipid droplet 0.5869792671041432 2.366240825356534 0.0179697510939791 0.999999933049735 0.4960740377762119 31 Q9H6V9,Q07065,Q01105 3 +Ciliary basal body 0.5850491601668876 2.333876699264178 0.0196021791531921 0.9999999852928254 0.5252230943693552 26 P28070,Q9H3S7,P31749,Q8IUD2,Q9BV73,O75419,Q2M1P5,A0AVF1,Q9P2S5,P15311,O43805,Q96C92,P41208 13 +Calcium channel complex 0.7585892787924933 2.2421163989251984 0.0249538504004573 0.9999999998995543 0.5945375038480532 9 Q8IYU8,Q9NWR8,P0DP25,Q9BPX6 4 +Endoplasmic reticulum golgi intermediate compartment 0.5322570726116261 2.207556066325223 0.0272752345850051 0.9999999999885484 0.5945375038480532 53 Q9BVK6,P30533,Q9Y282,P49257,Q13190,P80303,P24390,Q9Y3A6,Q08379,Q15363,P33908,O95070,Q03518,Q8N511,P49755,Q10472,P09429,Q8N3R9,O15260 19 +Golgi stack 0.5609228677769297 2.199958571675814 0.0278098344668136 0.99999999999306 0.5945375038480532 36 O95249,O00461,Q8WVQ1,Q9H4A5,P0CG08,Q10472,Q08379,O60763,Q9BZG1,Q9H4A6,Q8TBA6,Q15363,Q99996,Q10471,Q14789,Q10713,P98194,Q8NBZ7 18 +Respiratory chain complex iv 0.6863638184730045 2.109871119159901 0.0348694585148299 0.9999999999999908 0.5945375038480532 11 P22695,P00403,P14406 3 +Uniplex complex 0.8944730194202353 2.0950271367293807 0.0361685802401354 0.9999999999999972 0.5945375038480532 4 Q8IYU8,Q9BPX6 2 +Intrinsic component of golgi membrane 0.6987950067198084 2.0565305568937684 0.0397314040418963 1.0 0.5945375038480532 10 Q8TB61,Q6ZRP7,Q9Y282,Q10471,O95070,P98194 6 +Golgi associated vesicle membrane 0.5430781713747564 2.028591950327425 0.0424998691389333 1.0 0.5945375038480532 21 Q9Y287,O43731,Q8NDZ4,Q15363,Q8N511,P24390 6 +Proton transporting v type atpase complex 0.669641069242549 2.020832196603079 0.0432971386746547 1.0 0.5945375038480532 11 Q9Y487,Q93050 2 +Juxtaparanode region of axon 0.8721467852959378 2.006203730283934 0.0448345160526646 1.0 0.5945375038480532 4 Q8IXJ6 1 +Proteasome core complex 0.6124245816336343 2.005059390997417 0.0449566981509563 1.0 0.5945375038480532 15 P28072,P28070,P28074,P20618,P49721 5 +Myofilament 0.8098757381229473 1.9743678814631316 0.0483399273929991 1.0 0.5945375038480532 5 P67936,P09493 2 +Striated muscle thin filament 0.8098757381229473 1.9743678814631316 0.0483399273929991 1.0 0.5945375038480532 5 P67936,P09493 2 +Intrinsic component of endoplasmic reticulum membrane 0.499240411344843 1.9743024334163937 0.0483473643788505 1.0 0.5945375038480532 56 O75298,Q86XL3,Q8TCT9,Q15125,Q8TB61,Q9NQC3,Q9Y282,Q96A33,O75844,P49069,Q86UP2,O95470,Q86YN1,Q15629,Q03518 15 +Cilium 0.3752956266235584 1.9634046232710372 0.0495991770498924 1.0 0.5945375038480532 92 Q9BV73,Q2M1P5,Q15388,Q15154,Q9BZG1,Q10713,P41208,P28070,Q9NUQ9,Q9H3S7,P05023,P31749,P33176,O95721,P15311,A6NIH7,Q13501,O75419,Q9P2S5,O43805,Q96C92,Q8NCM8,Q92973,Q7Z4L5,Q8IUD2,Q15555,A0AVF1,Q9Y5K8,Q14141 29 +Proton transporting atp synthase complex coupling factor f o 0.7237047708960007 1.8838573934731535 0.0595842677346036 1.0 0.6429613441813244 7 P00846 1 +Mib complex 0.6650915444104715 1.8826533094353224 0.059747366813821 1.0 0.6429613441813244 10 Q5HYI7,Q13505 2 +Er ubiquitin ligase complex 0.7407617456387701 1.8804695300009335 0.0600441152620381 1.0 0.6429613441813244 6 Q9UBV2 1 +Golgi lumen 0.7823374751884519 1.8576715995017632 0.063215663967211 1.0 0.6429613441813244 5 O00461,Q9NX62,P30533 3 +Haus complex 0.8349441943640552 1.8565386121874885 0.0633768246916781 1.0 0.6429613441813244 4 Q9H6D7 1 +Respiratory chain complex iii 0.697093508079536 1.845377623154192 0.064982625918206 1.0 0.6429613441813244 8 Q9UDW1,P22695 2 +Vacuolar proton transporting v type atpase v0 domain 0.9218136278352254 1.8289997076717937 0.0673996520374888 1.0 0.6429613441813244 3 Q93050 1 +Proton transporting v type atpase v0 domain 0.9218136278352254 1.8289997076717937 0.0673996520374888 1.0 0.6429613441813244 3 Q93050 1 +Synaptic vesicle membrane 0.5430293348580901 1.8089180360386616 0.0704637379447941 1.0 0.6429613441813244 18 P09496,Q86Y82,P20020,O00429,O43760,O76024,O43752,Q92599,Q15286,P0DP25,O15126 11 +Myosin ii complex 0.8229197512585114 1.807744130885824 0.0706463327157909 1.0 0.6429613441813244 4 P35579,P35580,Q7Z406 3 +Intrinsic component of mitochondrial outer membrane 0.6052764018676982 1.7868565241018308 0.0739606808486847 1.0 0.6429613441813244 12 Q8IWA4,Q9GZY8,P57105,Q15388 4 +Nuclear inner membrane 0.5092813120972167 1.7770787500117962 0.0755552839139066 1.0 0.6432790994912987 21 Q9BTV4,Q99720,O94901,O75844,Q9UH99,Q9H1E5,Q03252,P50402,Q14739,P42704 10 +Epsilon dna polymerase complex 0.8113815763605099 1.7607411564312454 0.0782822234210223 1.0 0.6479219651178352 4 Q9NRG0 1 +Postsynaptic density membrane 0.6578043962935375 1.7438486810292864 0.0811854792425197 1.0 0.6479219651178352 9 Q99720,P57105,Q14168 3 +Mitotic spindle microtubule 0.7087066925953807 1.7355378107046604 0.0826455903302234 1.0 0.6479219651178352 6 Q9H6D7 1 +Respirasome 0.4922765676883317 1.7343620218014284 0.0828538691716034 1.0 0.6479219651178352 46 Q6DKK2,Q9UDW1,Q13423,P22695,P00403,P03886,O14949,O96000,O43676,Q86Y39,P14406 11 +Proton transporting atp synthase complex 0.5944827605104775 1.7248923071114517 0.084546882208969 1.0 0.6479219651178352 12 P00846,P56378,O75964,P06576 4 +Myelin sheath 0.583790576996125 1.709530224417895 0.0873527780327121 1.0 0.6479219651178352 13 Q8IXJ6,Q9NR77,Q8N3R9,P0DP25 4 +Transcription factor tfiid complex 0.6685443225615328 1.7064494816243791 0.0879244245080177 1.0 0.6479219651178352 8 Q15545,O00268,P23193,P29083,Q00403,P18074,P35269 7 +Compact myelin 0.888395500296026 1.6994943657053676 0.0892260752793099 1.0 0.6479219651178352 3 Q8IXJ6,Q9NR77 2 +Zymogen granule membrane 0.7938999111637525 1.6892050928022468 0.0911801333736941 1.0 0.6479219651178352 4 Q15363,P49755,Q13277 3 +Neurofilament 0.7863530219800056 1.658210027936033 0.0972750814326786 1.0 0.6681564016771077 4 P07196 1 +Caveola 0.5655444849342754 1.6532162856250916 0.0982868531997132 1.0 0.6681564016771077 14 P09601 1 +Ciliary transition zone 0.6550852815994178 1.6403606625939946 0.100930199366549 1.0 0.6681564016771077 8 Q15555,A6NIH7,Q15154,P41208 4 +Mitochondrial intermembrane space protein transporter complex 0.7799822327509576 1.6319953921049506 0.1026804568987871 1.0 0.6681564016771077 4 Q9Y5J7,Q9Y5J9,O60220 3 +Neurofibrillary tangle 0.8609067348450856 1.592257156432788 0.1113269353073751 1.0 0.6713774196451481 3 P07197 1 +Excitatory synapse 0.7204399897322442 1.5909711762819505 0.1116160626999085 1.0 0.6713774196451481 5 Q9UQB8,Q7L576 2 +Snare complex 0.5110153479487584 1.585912369701555 0.1127591894146586 1.0 0.6713774196451481 18 O95249,O43752,O95721,Q13277,Q13190,Q9P2W9 6 +Zymogen granule 0.7185267946463272 1.5826416581244358 0.1135031628580822 1.0 0.6713774196451481 5 Q15363,P49755,Q13277 3 +Transport vesicle 0.3542222948332287 1.5784037506907704 0.1144728841045457 1.0 0.6713774196451481 101 Q9BVK6,Q8TBA6,Q13190,P49257,Q9HD26,P24390,O95249,O00461,Q15019,Q9NR31,O00429,O43752,O60333,Q13277,Q92572,Q15363,O43731,Q15437,P49755,Q9BT78,O43760,Q9GZY8,O60763,P0DP25,O15027,O15260,Q14141 27 +Myosin filament 0.8564239194789773 1.5747188591319117 0.1153213527153391 1.0 0.6713774196451481 3 P35579,P35580 2 +Paraspeckles 0.6725200193359493 1.569724463327418 0.1164792273879355 1.0 0.6713774196451481 6 Q8WXF1,P23246 2 +Tubular endosome 0.7638026555715116 1.5652283063481018 0.1175293866106792 1.0 0.6713774196451481 4 Q9UNH7,Q9Y5X3 2 +Phagophore assembly site 0.6328012278933232 1.5301772964930722 0.1259728494627974 1.0 0.6796315316423545 8 Q9H6U6,Q5MNZ6 2 +Postsynaptic specialization membrane 0.5533819270326868 1.528060608937891 0.1264974904439066 1.0 0.6796315316423545 13 Q99720,Q15375,P57105,Q9NQX3,Q99996,P11142,Q14168 7 +Platelet alpha granule lumen 0.5531218365138064 1.526497325558866 0.1268860559932272 1.0 0.6796315316423545 13 P35609,Q9NUQ9,P10909,O43707,P12814 5 +Ubiquitin conjugating enzyme complex 0.7524811517413634 1.5183605026337723 0.1289235429880793 1.0 0.6796315316423545 4 Q5VTR2 1 +Beta catenin destruction complex 0.6612174653620095 1.5175120060607026 0.1291374645674239 1.0 0.6796315316423545 6 P25054,P49841 2 +Trans golgi network membrane 0.4765378478463787 1.505843017413052 0.1321074773864179 1.0 0.6838063176081064 28 Q9NX62,O43752,Q9H4A5,Q9UID3 4 +Mitochondrial protein containing complex 0.385172259665645 1.4795684472322654 0.138988452199416 1.0 0.7034359997426 164 Q7Z7F7,O60830,O60220,Q9Y5J7,Q13505,P22695,Q9Y5J9,P03886,Q9NS69,Q99595,O14949,Q86Y39,Q9BPX6,P00846,O14925,Q8N4H5,O75964,Q9UDW1,Q8IYU8,P56378,O43676,P21796,P14406,Q9NQ50,P00403,Q5HYI7,Q9NX63,O96000,P13073,Q567V2,Q8IWA4,Q9NWR8 32 +Protein lipid complex 0.6861347171369112 1.440985534695397 0.1495887694644437 1.0 0.7326632740973563 5 Q9UHG3 1 +Postsynaptic density intracellular component 0.7273840741859176 1.4141097672100764 0.1573296757955051 1.0 0.7386741192169562 4 Q9UQB8 1 +Derlin 1 retrotranslocation complex 0.7268204772783685 1.4117640124815307 0.1580194580836798 1.0 0.7386741192169562 4 Q9UBV2 1 +Neuron projection terminus 0.5156752604634118 1.3976072267095645 0.1622310470265047 1.0 0.7386741192169562 15 Q06787,Q9UQB8,Q05682,P11142,Q7L576,O75150,Q14141 7 +Intrinsic component of peroxisomal membrane 0.6761459766854631 1.3970989639289515 0.1623838133443698 1.0 0.7386741192169562 5 O43808,Q9Y5Y5 2 +Zona pellucida receptor complex 0.6751683189813609 1.3927993606598212 0.1636804718157902 1.0 0.7386741192169562 5 P49368,P78371 2 +Specific granule membrane 0.4552079218124614 1.3700000578482183 0.1706868835860699 1.0 0.7423382207563523 20 P30519 1 +Origin recognition complex 0.6150311646642852 1.3678422699991122 0.1713614533307415 1.0 0.7423382207563523 7 Q13416,P33993,Q9Y619 3 +Coated vesicle 0.334795285730477 1.3640584346448394 0.1725491752520622 1.0 0.7423382207563523 94 Q9BVK6,Q9Y282,P42892,Q13190,P49257,P50570,Q9HD26,P24390,Q9NR31,O43752,Q9Y3A6,Q08379,Q96AX1,Q8NDZ4,Q969X5,Q15363,Q5VW38,O95070,P11142,O15126,O43731,Q8N511,Q9UJY4,Q15437,P35606,P49755,O60763,O14641,O15027,Q9Y6B6 30 +Intraciliary transport particle 0.7152103583545172 1.3634072409990574 0.1727542002869333 1.0 0.7423382207563523 4 Q7Z4L5 1 +Intrinsic component of nuclear inner membrane 0.6124347232093603 1.355296243836898 0.1753231912663992 1.0 0.7423382207563523 7 Q14739,Q9UH99,O94901 3 +Centriole 0.4580051442654305 1.355042697004544 0.1754039539523886 1.0 0.7423382207563523 31 Q8IXJ6,Q9BV73,Q66GS9,Q9P2S5,O95684,P42858 6 +Cd40 receptor complex 0.7996411379892459 1.3518031630907543 0.1764382920086635 1.0 0.7423382207563523 3 Q9NR28 1 +Bloc complex 0.9313406333234696 1.3361843676690512 0.1814890192748754 1.0 0.7423382207563523 2 Q969F9 1 +Organelle inner membrane 0.4186404199603791 1.3326147725376425 0.1826582547980388 1.0 0.7423382207563523 258 Q7Z7F7,Q8NI60,P22830,Q70HW3,O95563,O60830,O60220,Q9Y5J7,Q13505,Q13423,P22695,Q9Y5J9,Q8N8Q8,Q9Y4W6,P03886,O60313,Q99595,O14949,Q9H1E5,Q03252,Q10713,P42704,Q86Y39,Q69YU5,Q9BPX6,P00846,O43772,O14925,P10909,O75964,Q9UDW1,Q9Y2C4,P56556,Q96EY7,Q8IYU8,Q53H12,P06576,P43304,Q14739,P56378,O43676,Q9Y6C9,P14406,Q9H2D1,Q9NPL8,Q9NQ50,P00403,O75208,Q5HYI7,Q53S58,Q9UDX5,Q9NX63,O96000,P24539,P13073,O95831,Q5T9A4,Q9BRT2,O75880,Q99720,Q9Y2R0,Q16540,Q567V2,Q6DKK2,Q9NWR8,P17152,O75844,Q9UG56,P50402,Q9UBX3,Q6P4A7 71 +Cop9 signalosome 0.5607420881001265 1.3264506348777598 0.1846904762533185 1.0 0.7423382207563523 10 Q99627,P61201,Q9UBW8,Q9BT78 4 +Dna replication preinitiation complex 0.5601740646582456 1.3233654947464837 0.1857138608197366 1.0 0.7423382207563523 10 P25205,O75419,P33993,Q14566,Q9BRT9,P33991 6 +Ciliary tip 0.5599031531018277 1.32189393380146 0.1862034727107879 1.0 0.7423382207563523 10 Q7Z4L5,Q15555,A0AVF1,Q8NCM8 4 +Cell trailing edge 0.6189446674425694 1.3208439904520517 0.1865533883880461 1.0 0.7423382207563523 6 P35579 1 +Nuclear outer membrane endoplasmic reticulum membrane network 0.4414485189696475 1.3166570196761294 0.1879536166214881 1.0 0.7423382207563523 331 P48449,Q9BT22,P30519,Q9Y282,Q15800,O60725,Q13190,Q9BQE5,Q12981,Q07065,P43307,P24390,Q5JRA6,Q16850,Q70UQ0,P04843,Q9NZ08,Q15392,O00264,Q86UE4,Q9Y6I9,Q86XL3,P09601,Q96G23,O75845,Q8N0U8,O43731,Q8N511,Q15629,Q9HD20,Q9BRR6,Q9P2W9,Q5T9L3,Q99720,Q6P179,Q06136,O43852,O15260,P67812,Q9NQC3,O95470,P51648,Q9UKU0,Q86YN1,Q9Y5M8,Q96KC8,O43865,P38435,Q96HY6,P16615,O75844,P50402,O95197,Q96A33,Q969V3,Q9UBV2,Q8WXH0,Q15125,O00429,Q8TD16,Q8IY17,Q03518,O43464,Q96S66,Q5BJF2,Q9Y2G5,P16435,O75298,Q10472,Q14849,Q96PC5,P62942,P07099,Q6NUM9,P42704,Q8NHH9,Q8TCT9,Q13438,Q15363,O95070,Q14739,Q8TB61,Q2TAA5,Q86UP2,Q15437,P49755,Q8WVQ1,P49069,O15027 89 +Main axon 0.5411659608887767 1.3107449245082083 0.1899439553971906 1.0 0.7423382207563523 11 Q8IXJ6,Q14168 2 +Endoplasmic reticulum tubular network 0.5221471560332658 1.301518762922771 0.1930809463770781 1.0 0.7450824249604988 12 Q00765,Q14974,Q8NHH9,Q9H6H4,Q9NQC3,P50402,Q15042 7 +Microtubule organizing center attachment site 0.7865600947306177 1.3003755967812494 0.1934722696140838 1.0 0.7450824249604988 3 Q8WXH0,O94901 2 +Spectrin 0.6981352982516316 1.2922048565137296 0.1962862102904494 1.0 0.7450824249604988 4 Q13813,Q01082 2 +Sarcoplasm 0.4429185577325994 1.2750771051411305 0.2022819520834884 1.0 0.75082436800309 20 O75298,P62942,P52789,P16615,O43852,Q8WXH0 6 +Nuclear outer membrane 0.532824142298006 1.263402962531367 0.2064444000209908 1.0 0.753720770895851 11 Q99720,P50402,Q8WXH0,Q6NUM9 4 +Organelle envelope lumen 0.4416825545662136 1.2591797357984589 0.2079654191917248 1.0 0.7545828084167892 43 O43464,O14925,O60220,Q9Y5J7,Q96AY3,Q9Y5J9,Q9NR28,Q9BRT2,O60313,Q8IYU8,Q9H4A6,Q53H12,Q96BR5,P52888,O95831,Q9BPX6 16 +Presynaptic cytosol 0.6864322971680819 1.2433821579591793 0.2137270418850803 1.0 0.7635503339502281 4 Q9UQB8 1 +Protein phosphatase type 2a complex 0.6385114122523965 1.2312275283446077 0.218237778247605 1.0 0.7643412866777483 5 P30154 1 +Mcrd mediated mrna stability complex 0.6368885345048656 1.2240656097375913 0.2209274780476118 1.0 0.7643412866777483 5 O60506 1 +Histone pre mrna 3 end processing complex 0.901746078721516 1.2208407018757437 0.2221463397378351 1.0 0.7643412866777483 2 P67809 1 +Endoplasmic reticulum lumen 0.3908822166601933 1.216576100930124 0.2237655402928653 1.0 0.7643412866777483 69 Q5JRA6,Q86UP2,P10909,Q6P179,Q13438,Q96AY3,Q9NZ08,P30533,Q32P28,O43681,O75718,Q9Y680,Q14257,P07942,Q9NWM8,O43852,Q07065 17 +Centriolar satellite 0.4390732232390839 1.2059242572139628 0.2278466965866967 1.0 0.7643412866777483 28 Q13045,P11413,P33176,Q8NI35,O60271,Q15154,Q86UY6,Q86YS7,Q8WXW3,Q53EZ4,Q12873,Q00013,Q7Z4H7,Q9Y5A9,Q03518 15 +Microbody membrane 0.4381086013785311 1.1926017712884447 0.2330253718259314 1.0 0.7643412866777483 31 O75381,P40855,Q9NR77,Q15067,Q8TB36,O00116,O43808,P50542,P51648,Q9UKU0 10 +Organelle membrane contact site 0.4439781211358418 1.1891393300150512 0.2343848438851798 1.0 0.7643412866777483 19 Q96TC7,Q96S66,O95772,Q14849,O43865,Q15388 6 +Wnt signalosome 0.7575209096571536 1.1863880405058298 0.2354690924771612 1.0 0.7643412866777483 3 P25054 1 +Copii coated er to golgi transport vesicle 0.4359953444468712 1.1745481570460534 0.2401755347481748 1.0 0.7717441792524348 32 Q9NR31,Q9Y3A6,Q9BVK6,Q08379,Q9Y282,O60763,Q15363,P49257,Q13190,O95070,O15027,Q9Y6B6,Q15437,P49755 14 +Prefoldin complex 0.6696774552678528 1.1735192360336415 0.2405876475386295 1.0 0.7717441792524348 4 O15212 1 +Organelle subcompartment 0.4461550481057288 1.1685469131051782 0.2425862275217702 1.0 0.7733310026462702 399 P48449,Q9BT22,P30519,Q9Y282,Q15800,O60725,Q13190,Q9BQE5,Q12981,Q10713,Q07065,P43307,P24390,Q5JRA6,O00461,Q16850,P0CG08,Q70UQ0,P04843,Q9NZ08,Q15392,O00264,Q8NBZ7,P98194,Q86UE4,Q9Y6I9,Q86XL3,P09601,Q96G23,O75845,Q8N0U8,O43731,Q8N511,Q15629,Q9HD20,Q9BRR6,Q9P2W9,Q5T9L3,Q99720,Q6P179,Q9UID3,Q06136,O43852,O15260,Q9H4A5,P67812,Q9NX62,Q9NQC3,Q9BZG1,O95470,P51648,Q9UKU0,O43752,Q9HC07,Q86YN1,Q9Y5M8,Q96KC8,O43865,P38435,Q96HY6,Q9NPR9,Q4J6C6,P16615,O75844,P50402,O95197,Q96A33,Q969V3,Q8TBA6,Q9UBV2,Q8WXH0,O95249,Q15125,O00429,Q08379,Q9H4A6,Q8IY17,Q03518,O43464,Q96S66,Q9BWS9,Q5BJF2,Q9Y2G5,P16435,O75298,Q10472,Q14849,Q96PC5,P62942,P07099,Q13439,Q96ED9,Q6NUM9,Q8NHH9,Q8TCT9,Q13438,Q15363,O95070,Q14739,P53365,Q8TB61,Q2TAA5,Q9UJY4,Q99996,Q86UP2,Q15437,P49755,Q8WVQ1,P49069,O15027 110 +Schmidt lanterman incisure 0.8881325836046179 1.168066119813608 0.2427800952325283 1.0 0.7733310026462702 2 Q8IXJ6 1 +Bleb 0.6219012344950468 1.1579361143881974 0.2468901083063417 1.0 0.7768863830918921 5 P09493 1 +Sarcoplasmic reticulum membrane 0.5296115388153936 1.1569142144758429 0.2473074106439612 1.0 0.7768863830918921 10 P16615,O75298,P62942,Q8WXH0 4 +Chloride channel complex 0.5823908904824509 1.1497503672590472 0.250246702903302 1.0 0.7811348975336624 6 Q9C0H2,Q96S66 2 +Postsynaptic endosome 0.6625744461797571 1.143934719777005 0.2526507108167291 1.0 0.7811348975336624 4 Q4V328,Q86Y82 2 +Mcm complex 0.5796766122654664 1.13703945625699 0.2555217917010539 1.0 0.7819073717169608 6 P33993,P33991,P25205 3 +Glial cell projection 0.6167519807280814 1.1352293113904843 0.2562792512807363 1.0 0.7819073717169608 5 Q8IXJ6,Q06787 2 +Endoplasmic reticulum tubular network membrane 0.8762947617638368 1.122372251076353 0.261704197767755 1.0 0.7856496386242791 2 Q9NQC3 1 +Trans golgi network 0.38496822670065 1.121472194918192 0.2620869206101781 1.0 0.7856496386242791 68 P53365,Q9NPR9,Q9H4A5,Q9BWS9,Q4J6C6,Q9NX62,O43752,Q9HC07,Q9UID3,Q13439,Q96ED9,Q9H4A6,Q5T9L3 13 +Schaffer collateral ca1 synapse 0.464561245592103 1.1198989665297303 0.2627568187520466 1.0 0.7856496386242791 16 Q9UQB8,P07196,Q08209 3 +Proteasome complex 0.4198284046209222 1.1057751293301183 0.2688238623362216 1.0 0.7911999515242291 48 P28072,P28070,O00231,Q99436,P51665,Q05086,P28074,P20618,Q9UL46,P49721,Q9UMX0,P61289,Q06323 13 +Signal peptidase complex 0.7362698368126885 1.103325568869947 0.2698858067389482 1.0 0.7911999515242291 3 P67812 1 +Photoreceptor connecting cilium 0.6093988665559589 1.1028270273781433 0.270102288610357 1.0 0.7911999515242291 5 Q15555,P41208 2 +Peptidase complex 0.4004956427133944 1.0946633235348535 0.273664162254337 1.0 0.7990642686336571 60 O43464,P28072,P28070,O00231,P67812,Q9Y4W6,Q99436,P51665,Q05086,P28074,P20618,P49721,Q9UMX0,P61289,Q06323 15 +Integral component of synaptic vesicle membrane 0.5565673130651239 1.0844421059271587 0.2781688231718346 1.0 0.8038370430576357 7 O43752,O76024,Q86Y82,O15126 4 +Platelet alpha granule 0.4402769004791391 1.0820276649148743 0.2792402353557914 1.0 0.8038370430576357 18 P35609,Q9Y6I9,Q96JJ7,Q9NUQ9,P10909,O43707,Q9NTK5,P12814 8 +Photoreceptor inner segment 0.6020270927941935 1.0703796971638762 0.2844484341911806 1.0 0.8038370430576357 5 Q9BV73,Q15555,P05023 3 +Microbody 0.3980924763455486 1.070197793526361 0.2845302873365067 1.0 0.8038370430576357 60 O75381,Q96CN7,P40855,O00429,Q9NR77,Q15067,P08670,Q9GZY8,Q13011,O15254,Q9UKU0,P51648,Q8N4Q0 13 +Retromer complex 0.5123573438184283 1.0627782899923963 0.2878825070808624 1.0 0.8038370430576357 10 Q9Y5X3,Q96QK1,Q5VZ89,Q9UNH7 4 +Dynactin complex 0.6001080655076172 1.0619405446142849 0.2882626772990131 1.0 0.8038370430576357 5 Q13561,O75935,Q9UJW0 3 +Presynaptic cytoskeleton 0.8558745190884898 1.0440885370960726 0.2964444288095045 1.0 0.8184905362981327 2 P07196 1 +Paranodal junction 0.8517312814442164 1.028302326983883 0.3038076368076989 1.0 0.8286489734485442 2 Q8IXJ6 1 +Postsynaptic cytoskeleton 0.8517312814442164 1.028302326983883 0.3038076368076989 1.0 0.8286489734485442 2 P07196 1 +Ruffle membrane 0.4128948597239031 0.9823805506160248 0.3259124044295274 1.0 0.8469855726827508 34 Q9BZG1,P09493,P31751 3 +Golgi associated vesicle 0.4121028178242502 0.9777554538245706 0.3281952877683984 1.0 0.8469855726827508 32 Q9Y287,O43731,Q8NDZ4,Q15363,Q8N511,P49755,P24390 7 +Messenger ribonucleoprotein complex 0.5442751997979771 0.9716747016498394 0.3312124062487465 1.0 0.8523573505440906 6 P67809,Q06787,Q99729 3 +Tim22 mitochondrial import inner membrane insertion complex 0.8339745486830441 0.9610886839259574 0.3365075789704947 1.0 0.8563083922964266 2 Q9Y5J7 1 +Cis golgi network membrane 0.8313110387688682 0.9510744170934332 0.3415666004558741 1.0 0.8619589280202253 2 Q9NPR9 1 +Actomyosin 0.4073371629465129 0.9464787248054388 0.3439044686227626 1.0 0.8627361389247049 29 P06753,P35580,P35579,O43707,P09493,P12814,P67936 7 +Endopeptidase complex 0.3938380055967125 0.944065376246102 0.3451362411654131 1.0 0.8627361389247049 55 O43464,P28072,P28070,O00231,Q99436,P51665,Q05086,P28074,P20618,P49721,Q9UMX0,P61289,Q06323 13 +Dendritic shaft 0.5371741492973314 0.9386820142028064 0.3478940304832885 1.0 0.8627361389247049 6 Q9UQB8 1 +Endocytic vesicle 0.3044923943704967 0.9375633464055708 0.3484688553121986 1.0 0.8627361389247049 92 O00461,Q9Y4G8,O43752,Q9Y487,P08670,Q93050,Q14C86,Q9BZG1,O14641,Q8WTV0,Q5T9L3 11 +Plasma membrane raft 0.3957746783694401 0.9095591466803494 0.3630550519156017 1.0 0.8743832394319647 20 P09601 1 +Dendrite cytoplasm 0.4687176375462472 0.898849211709622 0.3687329833897164 1.0 0.8812127055567623 11 Q9UQB8,P23246,P33176 3 +Terminal bouton 0.5282298757556388 0.8972613180716241 0.3695794922416366 1.0 0.8812127055567623 6 Q7L576,P11142 2 +Micos complex 0.6019228911237654 0.8935877057914106 0.3715425266785424 1.0 0.8812127055567623 4 Q9NX63 1 +Ciliary membrane 0.5584804780185284 0.8801689235246701 0.3787678057615262 1.0 0.8812127055567623 5 O95721,Q15019 2 +Hulc complex 0.8117786327315795 0.8782601693102041 0.3798025458667304 1.0 0.8812127055567623 2 Q5VTR2 1 +Intrinsic component of synaptic vesicle membrane 0.4505539400481644 0.8757018490833575 0.3811921398705227 1.0 0.8812127055567623 12 Q86Y82,P20020,O43752,O76024,Q15286,O15126 6 +Chaperonin containing t complex 0.5019419612935798 0.8740619031974802 0.3820845430240627 1.0 0.8812127055567623 8 P49368,P78371 2 +Lewy body 0.8088191772713841 0.8673320492275205 0.3857601012661631 1.0 0.8855812973554817 2 Q13501 1 +Neuromuscular junction 0.3995151238743815 0.8583608398441948 0.3906932441634829 1.0 0.8875849013290099 19 P07196,P57105,Q14168 3 +Ccr4 not core complex 0.5860043853746917 0.8290896104658491 0.4070537022984366 1.0 0.914880506469998 4 Q9NZN8 1 +Mitochondria associated endoplasmic reticulum membrane 0.467238697763219 0.8180812189505774 0.413310812205153 1.0 0.9228582105855254 10 Q96S66,Q15388,O43865 3 +Intraciliary transport particle b 0.6598361143031735 0.8107026878242397 0.4175364294389512 1.0 0.9232419592691372 3 A0AVF1 1 +Potassium channel complex 0.6593186942753517 0.8087734053932211 0.4186454961693853 1.0 0.9234528983300484 3 P0DP25 1 +Aggresome 0.4500799943574075 0.7938854779475398 0.4272621045780997 1.0 0.937917535591925 11 Q9UMX0,O14641 2 +Nucleotide excision repair complex 0.5368754600493867 0.7873928410001373 0.431051936256748 1.0 0.9416985945561088 5 P18887,P19447,P41208 3 +Pseudopodium 0.4705945904782669 0.7732848166144805 0.4393538395513534 1.0 0.9450117940775646 9 P35609,P12814 2 +Crd mediated mrna stability complex 0.5010623996961353 0.7727356990649031 0.4396788147109285 1.0 0.9450117940775646 6 P67809 1 +Sperm annulus 0.6495365873207752 0.7724805571647194 0.4398298580558588 1.0 0.9450117940775646 3 Q14141 1 +Inclusion body 0.386271333168927 0.7662767517485551 0.4435116483121817 1.0 0.9487552298450246 32 P07197,Q13501,Q9UMX0,P10909,P12270,O14641,P42858,P13807 8 +Transporter complex 0.3520077238791558 0.7116725858713476 0.4766675473751425 1.0 0.9680051523161998 66 P62942,O60220,Q9Y5J7,Q9Y5J9,P22695,P03886,O14949,Q86Y39,Q9BPX6,O75381,Q9UDW1,P56556,Q8IYU8,O43676,Q96S66,O96000,P0DP25,Q9C0H2,Q9NWR8 19 +N terminal protein acetyltransferase complex 0.6323268206039041 0.7095525179313845 0.4779816730921238 1.0 0.9680051523161998 3 Q9GZZ1,Q9BXJ9 2 +Nata complex 0.6323268206039041 0.7095525179313845 0.4779816730921238 1.0 0.9680051523161998 3 Q9GZZ1,Q9BXJ9 2 +Neuronal ribonucleoprotein granule 0.7632435631843768 0.703355884957924 0.481833991505245 1.0 0.9705647900240476 2 Q99729 1 +Neuron projection membrane 0.4560314276005053 0.6992679653812545 0.4843845829337216 1.0 0.9705647900240476 9 Q01082,Q14168 2 +Cytoplasmic ubiquitin ligase complex 0.463480913947859 0.6853158667360517 0.4931446215457933 1.0 0.9763228580073724 8 Q9UBV2 1 +Golgi apparatus 0.3997072454410982 0.6833797427965688 0.4943669169997033 1.0 0.9763228580073724 335 Q7RTS9,Q9Y287,Q9Y282,P80303,Q13190,Q10713,Q16739,Q9NX40,Q9HD26,P24390,O00461,P0CG08,Q93050,Q15392,Q5VW38,P33908,Q8NBZ7,Q8NCH0,O43731,Q9P2W9,Q5T9L3,Q9UID3,Q9H9S5,Q7LGA3,O43852,Q8NEY8,O15260,Q9H4A5,Q9NX62,Q9Y2T2,Q9BZG1,P10909,O43752,Q9HC07,Q8NDZ4,Q9UQB8,P25054,Q9NPR9,Q4J6C6,Q8N2A8,Q92896,O95197,Q8TBA6,P42858,Q5VU43,O95249,O00429,O60476,Q08379,Q8TD16,Q9H4A6,Q96S66,Q9BWS9,Q68CQ7,Q6ZRP7,Q9Y2G5,P49815,Q10472,Q8N3R9,Q99805,P30533,Q13439,Q96ED9,Q5VZ89,Q8NEW0,Q9NR31,O95721,Q15363,O95070,O95456,P53365,Q8TB61,Q9UJY4,Q99996,Q8NCM8,P49755,Q8WVQ1,Q8IUD2,O15027 79 +Mll1 2 complex 0.3986075540112395 0.682316387057969 0.4950389133167983 1.0 0.9763228580073724 16 Q03164 1 +Ikappab kinase complex 0.756436815625928 0.6796838382122248 0.4967046715840806 1.0 0.9763228580073724 2 Q8IUD2 1 +Bcl 2 family protein complex 0.7555489789878693 0.6766142460772164 0.4986507379196592 1.0 0.9769264994512032 2 Q07820 1 +Centriolar subdistal appendage 0.6220600483139359 0.6726468742349333 0.5011719731814537 1.0 0.9773324945356956 3 Q14203 1 +Escrt complex 0.425513302098997 0.6576882224161855 0.5107384918599118 1.0 0.9773324945356956 11 O43633,Q8WUX9,O14964,Q9BRG1 4 +Mitochondrial envelope 0.398768364893171 0.6572678461330391 0.5110087074663885 1.0 0.9773324945356956 338 Q7Z7F7,Q70HW3,O60830,O95563,P22830,Q13505,Q13423,Q8N8Q8,P03886,Q9NS69,Q99595,Q12981,Q10713,Q69YU5,P00846,Q07820,P52789,Q8N4H5,P30536,O75964,Q9UDW1,Q9Y2C4,Q96EY7,Q53H12,Q8WY22,O00264,O43676,P14406,Q8N0X7,Q9H2D1,Q9NPL8,P09601,Q9HCL2,Q9NR28,Q9NVT9,Q5HYI7,O43169,P52888,P24539,Q5T9A4,Q9BRT2,Q9BYT8,Q9Y2R0,Q567V2,Q9UBX3,Q6P4A7,Q8NI60,P57105,P22695,Q8WWV3,O14949,Q9UKU0,Q9BPX6,P10909,Q96AY3,Q96A26,Q8IYU8,P21796,Q9NQ50,Q53S58,O95831,Q6DKK2,P0DP25,Q8N2A8,Q9NWR8,Q9BXK5,Q9Y5J7,Q9Y5J9,O60313,Q86Y39,O43772,O14925,O00429,Q9H4A6,P43304,P56378,Q9Y6C9,O43464,P00403,Q9UDX5,Q9NX63,O96000,P13073,P45880,Q9GZY8,Q8IWA4,O60220,Q9Y4W6,Q96TC7,P56556,P06576,O15294,O75208,O75880,P17152,Q96BR5,Q9UG56 97 +Leading edge membrane 0.3672906509432417 0.6272974361898636 0.5304642836986677 1.0 0.9822214683932649 48 P31751,P25054,Q9BZG1,P09493,Q14168 5 +Proteasome accessory complex 0.3561691093970874 0.5987282747076585 0.5493540990164134 1.0 0.9984841656878904 21 O00487,O00231,Q13200,P51665,O43242,Q9UL46,Q9UNM6,P17980,P61289,Q06323 10 +Rough endoplasmic reticulum 0.3664698809538234 0.5952217838480633 0.5516952308619913 1.0 0.9984841656878904 37 Q9Y5M8,Q9UQB8,Q5BJF2,P30533,Q96A33,Q9H9S5,Q07065 7 +Intermediate filament 0.3521678171387873 0.5689634899844277 0.5693809171752968 1.0 1.0 21 P07197,O75298,P07196,Q9NZQ3,P48681,P08670,Q16352,P02545,Q03252 9 +Microtubule 0.302767610429114 0.5508914198374387 0.5817081096044463 1.0 1.0 132 O43633,Q9H0B6,O60313,Q96ED9,O94927,P42704,Q9BSJ2,Q96TC7,P33176,O00429,O60333,Q08379,Q96DB5,Q9H6D7,Q9H6U6,Q9Y5M8,Q9UQB8,P78371,P25054,Q8NCM8,Q96JB5,P16949,Q8IXJ6,Q15555,P0DP25,Q8WUX9,P50402,P49368 28 +Er to golgi transport vesicle membrane 0.3493310635152785 0.5479905388520582 0.5836983992657829 1.0 1.0 21 Q9NR31,O60763,Q15363,P49257,Q13190,O15027,Q15437,P49755 8 +Postsynaptic specialization intracellular component 0.474527577903477 0.531368446866234 0.5951634823574681 1.0 1.0 5 Q9UQB8 1 +Gap junction 0.5069588392063851 0.5246572004564489 0.5998215151463473 1.0 1.0 4 Q16643,Q07157,Q99797 3 +Cyclin a2 cdk2 complex 0.7090855282628035 0.5226485295115361 0.6012188624355013 1.0 1.0 2 P20248 1 +Spindle microtubule 0.356484124593019 0.5211831009590765 0.6022392252352893 1.0 1.0 34 O43633,Q96TC7,Q96DB5,P0DP25,O94927,Q9H6D7 6 +Torc1 complex 0.5772646536412186 0.5185826933706571 0.6040517803690091 1.0 1.0 3 P42345,Q9Y4R8 2 +Ribbon synapse 0.5747176792565161 0.5102223888339913 0.6098956686265162 1.0 1.0 3 P16615 1 +Intrinsic component of postsynaptic density membrane 0.5742404129353825 0.5086611868672942 0.610989732536154 1.0 1.0 3 Q15375 1 +Early endosome 0.28599092000918 0.5085878126297194 0.6110411733599042 1.0 1.0 109 P31751,P42858,Q9Y5X3,Q9H3S7,O43752,Q9HC07,Q9UNH7,Q5VW38,Q9H223,O60749,Q15075,Q9UJY4,Q96C92,Q15276,Q5T9L3,Q86YV9,Q4V328,O14964,Q9Y2I1,Q567U6,Q92544,Q96QK1,Q5T1M5 23 +Microtubule associated complex 0.3518071344267315 0.50761861443987 0.6117208337871762 1.0 1.0 51 Q13409,Q9H0B6,Q2M1P5,Q96P70,O94927,Q7Z4H7,Q13561,P33176,O60333,O75935,Q9Y3P9,Q9H6D7,Q9UJW0,Q14203,P12270,Q8NCM8,O95793,Q15555,Q15058 19 +Lsm2 8 complex 0.4932069774758655 0.4756962824701911 0.634290769779954 1.0 1.0 4 P62310,Q9UK45 2 +Postsynaptic cytosol 0.4310895881160517 0.4687479558527955 0.6392498043343555 1.0 1.0 6 Q9UQB8 1 +Spectrin associated cytoskeleton 0.489157076126506 0.4615793845182998 0.6443829811416708 1.0 1.0 4 Q01082 1 +Growth cone membrane 0.6874815034033779 0.4562859176683696 0.6481843891513974 1.0 1.0 2 Q96A65 1 +Presynaptic active zone membrane 0.4810005403815586 0.433595800346024 0.6645819849759542 1.0 1.0 4 Q13277,P27824 2 +Myosin complex 0.3721319569228231 0.4287202783863126 0.6681268014240391 1.0 1.0 12 Q7Z406,P35580,O00159,P35579,P60660 5 +Ccr4 not complex 0.4148856062231052 0.42838620791955 0.6683699643392107 1.0 1.0 7 Q9UKZ1,Q9NZN8 2 +Centrosome 0.3172981510841064 0.4276550710633621 0.6689022649859888 1.0 1.0 174 Q13409,Q9BV73,P50991,Q15154,P28074,Q96ED9,Q86YS7,P50570,O94927,Q9NTK5,Q00013,Q5VU43,Q7Z4H7,P41208,Q9BSJ2,Q13561,P52789,P33176,O95721,O60271,Q8TD16,Q8WXW3,O75935,Q8N1F7,Q9Y3P9,Q9H6D7,Q03518,Q8WYA6,Q14203,P49841,Q66GS9,O75419,Q3YEC7,P25054,Q9P2S5,Q9H814,O95684,O43805,Q99996,Q96C92,O75116,Q96JB5,Q13045,Q6DKK2,Q8IXJ6,Q8IUD2,A0AVF1,P0DP25,P06493,O43292,Q86UY6,P50402,Q9Y5K8 53 +Cytoplasmic exosome rnase complex 0.3816898314941282 0.4258107109089968 0.6702457815377056 1.0 1.0 11 Q13868,O00178 2 +Astrocyte projection 0.6768274637466751 0.4249897394439917 0.6708441545351342 1.0 1.0 2 P05198 1 +Azurophil granule membrane 0.3380446644899699 0.4238949743829406 0.6716424094689413 1.0 1.0 26 Q07065,O15260 2 +Extrinsic component of endosome membrane 0.4770442581661971 0.4202475399239599 0.6743046289099803 1.0 1.0 4 Q4V328 1 +Neuron spine 0.342801845328627 0.4187210264689773 0.6754200270114294 1.0 1.0 33 P35609,Q7L576,Q08209,Q9UQB8,O43815,Q15075,P12814,Q14168 8 +Phagocytic vesicle membrane 0.3370188408652059 0.4092689634600505 0.6823422894652484 1.0 1.0 27 Q9BZG1,Q9Y487,Q93050 3 +Cell body membrane 0.6667653151820111 0.3963678680319378 0.6918336666755525 1.0 1.0 2 P55011 1 +Magnesium dependent protein serine threonine phosphatase complex 0.3914125837757325 0.3889803125238942 0.6972907101226324 1.0 1.0 9 P30154,Q08209 2 +Dendritic spine membrane 0.6617342408996791 0.3824124753381092 0.7021554383247652 1.0 1.0 2 P20020 1 +Septin cytoskeleton 0.408656824530983 0.3798189900549192 0.7040797848587546 1.0 1.0 6 Q15019,Q14141 2 +Cytoplasmic side of endosome membrane 0.6578869488014254 0.3719053873199356 0.7099632938910934 1.0 1.0 2 P20339 1 +Lsm1 7 pat1 complex 0.5291007111212066 0.3696316227672895 0.7116569857369373 1.0 1.0 3 P62310 1 +Photoreceptor outer segment 0.4059708648813571 0.3695542562451004 0.7117146399505643 1.0 1.0 6 Q9BV73,Q15555 2 +Histone methyltransferase complex 0.3266469991622003 0.3667913381555516 0.7137746691725382 1.0 1.0 23 Q03164 1 +Stereocilium bundle 0.3920062511763224 0.3605412111730834 0.7184424438144008 1.0 1.0 8 Q00013,Q9Y6M7 2 +Cytosolic region 0.3956071082077583 0.3502686621262704 0.7261370813915697 1.0 1.0 7 Q9UQB8 1 +Membrane protein complex 0.3674993525171138 0.3385894697483375 0.7349190164448567 1.0 1.0 307 O43633,P62942,O60830,P67812,Q9Y5J7,Q13505,Q9Y2T2,P22695,Q9Y4W6,P03886,Q9NS69,Q99595,O14949,Q13190,Q12981,Q9UBV2,Q8WXH0,Q86Y39,Q5VZ89,Q9BPX6,P00846,O95249,O14925,Q9Y5X3,Q8N4H5,Q9NR31,Q8TCT9,O75964,Q9UDW1,O43752,Q13438,O95721,Q13277,Q93050,P56556,Q8IYU8,Q8NDZ4,Q9UNH7,P06576,P56378,O43676,P21796,P14406,Q03518,O43464,Q96S66,Q9Y5M8,Q9Y487,P25054,P00403,Q9NR28,Q5HYI7,P05023,Q8N511,Q9NX63,O96000,Q99996,P04843,P13073,Q15437,Q9P2W9,P49755,P45880,Q9Y5K8,P0DP25,Q8WUX9,P09429,Q8IWA4,Q9C0H2,Q9NWR8,Q9BRG1 71 +Scf ubiquitin ligase complex 0.386411230195303 0.3374373588212936 0.7357872260722416 1.0 1.0 8 Q96K76 1 +Hippocampal mossy fiber to ca3 synapse 0.4453657092093464 0.31927251792134 0.7495198705299775 1.0 1.0 4 P63104,O60716,Q15375 3 +Transport vesicle membrane 0.3321207991824668 0.3184235757881118 0.7501636573246606 1.0 1.0 46 P09496,Q9NR31,O00429,O43752,O43760,Q15286,O60763,P0DP25,Q15363,P49257,Q13190,O15027,Q9Y6B6,Q15437,O15126,P49755 16 +T tubule 0.3869119563783976 0.3166075944608831 0.7515413724878435 1.0 1.0 7 P35241,O75298,P05023 3 +Anchored component of synaptic vesicle membrane 0.4138033175355406 0.3115816862398218 0.7553584541019454 1.0 1.0 5 P20339,P61020,P20337,Q15286 4 +Dynein complex 0.3578256613630179 0.3091662554048592 0.757195061561057 1.0 1.0 11 Q13561,Q13409,Q14203,P12270,Q8NCM8 5 +Rna cap binding complex 0.412618255909001 0.3077102222721531 0.7583028406600743 1.0 1.0 5 Q7L576,Q06787 2 +Axon cytoplasm 0.317073598800927 0.2924299167760871 0.7699579371132357 1.0 1.0 24 P07196,O60333,Q9Y2T2,O60313,Q14168 5 +Nucleotide activated protein kinase complex 0.427598460171737 0.26780333020569 0.7888507071979358 1.0 1.0 4 P10644,P54619,P13861 3 +Amphisome 0.3673219282688599 0.2621126719408856 0.7932345774396592 1.0 1.0 8 O43633,Q13501 2 +Rpap3 r2tp prefoldin like complex 0.3716204452527518 0.2601026652921416 0.7947845820620072 1.0 1.0 7 O15212 1 +Anaphase promoting complex 0.3471589177149553 0.2600649692627396 0.7948136588914898 1.0 1.0 11 Q9UJX4 1 +Endoplasmic reticulum exit site 0.3130980656980801 0.2582413428444418 0.7962206527245672 1.0 1.0 19 Q5JRA6,Q9NR31,Q9Y3A6,O15027,Q15437,Q96PC5 6 +Gemini of coiled bodies 0.3963270142179961 0.2564395916623394 0.7976114199198254 1.0 1.0 5 O75312,Q8TEQ6,Q9UHI6,Q16637 4 +Endoplasmic reticulum 0.3990575383738641 0.2554742291791177 0.7983568454987524 1.0 1.0 521 Q9H6V9,P48449,Q9H2J4,Q9BT22,P30519,Q9Y282,Q8TBX8,Q15800,P84157,O43681,O60725,P80303,Q13190,Q9BQE5,Q12981,Q07065,P43307,P24390,Q5JRA6,Q16850,P52789,Q70UQ0,P30536,P04843,P05023,Q9NZ08,Q15392,Q01105,Q15293,P33908,Q14257,Q14BN4,Q9NWM8,O00264,P98194,Q86UE4,Q9Y6I9,Q9P2J5,Q86XL3,P09601,Q96G23,Q8IY95,O75845,Q8N0U8,O43731,Q8N511,Q15629,Q9HD20,Q9BRR6,Q9P2W9,Q5T9L3,Q99720,Q92791,Q6P179,O95302,Q06136,Q9H9S5,O43852,O15260,P67812,Q9NQC3,Q9Y680,O95470,P51648,Q9UKU0,P10909,Q96AY3,Q86YN1,Q9Y5M8,Q96KC8,Q9UQB8,O43865,Q9UMX0,P38435,Q96HY6,Q9UMX5,Q86YV9,P16615,O75844,P50402,O95197,Q96A33,Q969V3,P42858,Q9UBV2,Q8WXH0,Q8IVL6,Q15125,O15173,O00429,O60476,Q32P28,Q8IY17,Q03518,O43464,Q96S66,Q5BJF2,O60506,Q9Y2G5,P16435,O75298,Q10472,Q14849,O75718,Q96PC5,P62942,P30533,P07099,Q6NUM9,P29692,P07942,Q8NHH9,Q9NR31,Q8TCT9,Q13438,Q15363,O95070,Q14739,O95456,Q13501,Q8TB61,Q2TAA5,Q86UP2,Q15437,P49755,Q8WVQ1,P55327,P49069,O15027 129 +Phagocytic vesicle 0.3242086495795494 0.2552571447040894 0.7985244973293675 1.0 1.0 46 Q9BZG1,Q9Y487,P08670,Q93050 4 +Eukaryotic translation initiation factor 4f complex 0.3700628357205693 0.2545532042055777 0.7990682063077459 1.0 1.0 7 P23588,Q15056 2 +Pore complex 0.3515483465900041 0.2474293312530084 0.8045759766754452 1.0 1.0 10 P21796 1 +Proton transporting v type atpase v1 domain 0.3674749237870433 0.245421420883104 0.8061301446236988 1.0 1.0 7 Q9UI12,Q9Y5K8,P21281 3 +Polymeric cytoskeletal fiber 0.3117116748328527 0.2447166961980324 0.8066757993547942 1.0 1.0 189 O43633,P07197,Q9H0B6,Q9NZQ3,O60313,Q96ED9,Q03252,O94927,P12814,P42704,Q9BSJ2,Q13561,Q96TC7,P33176,O00429,O60333,Q08379,Q96DB5,Q9H6D7,Q9H6U6,Q9Y5M8,Q9UQB8,Q5M775,P78371,P25054,P08670,P48681,Q8NCM8,P09493,P67936,Q96JB5,P35609,O75298,P07196,P06753,P16949,Q8IXJ6,Q15555,P0DP25,Q8WUX9,P50402,Q15058,P49368 43 +Nadh dehydrogenase complex 0.3105129373707864 0.2324581814606176 0.8161821639877243 1.0 1.0 26 O43676,Q86Y39,O96000,P03886 4 +9plus0 non motile cilium 0.3405852107480592 0.2308871281765805 0.8174024908179671 1.0 1.0 11 Q9BV73,Q15555,Q15019,P41208 4 +Intermediate filament cytoskeleton 0.3175756039652149 0.2297462846834226 0.8182889267723656 1.0 1.0 34 P07197,O75298,P07196,Q9NZQ3,Q8WXH0,P48681,Q3SXM5,P08670,Q9H6U6 9 +Contractile fiber 0.3169026332498988 0.2272934947385377 0.8201955311925961 1.0 1.0 55 P35609,O75298,Q13501,P62942,P06753,Q08209,P0DP25,O43707,P09493,P12814,Q8WXH0,P67936,Q5VU43,Q01082 14 +Rna polymerase ii transcription repressor complex 0.5969221663214026 0.2262491719080507 0.8210076283059107 1.0 1.0 2 Q9UHI6 1 +Nlrp3 inflammasome complex 0.5841965078425632 0.2011691876539253 0.8405662836529033 1.0 1.0 2 Q9H6R0 1 +Inflammasome complex 0.5841965078425632 0.2011691876539253 0.8405662836529033 1.0 1.0 2 Q9H6R0 1 +Ubiquitin ligase complex 0.3021985585018724 0.2008401729686265 0.8408235494005569 1.0 1.0 66 O95155,Q9BTE7,Q9UBS8,Q92564,Q92990,Q9Y4X5,Q13438,Q5VTR2,Q96P70,Q96DE5,Q9UBV2,Q9Y297,Q9UJX4,Q96K76,O75150,Q8IUR7 16 +Presynapse 0.2562167314494032 0.196647430497818 0.8441034510660854 1.0 1.0 97 Q9BVK6,O15400,Q96CX2,P61421,P50570,P51116,P42858,Q06787,Q15019,O00429,O43752,O60333,O95721,Q13277,P11142,Q07021,Q7L576,Q92905,O15126,P27824,Q9UQB8,Q15286,Q05682,Q9BT78,P09496,P07196,O43760,O76024,Q8IUD2,O14936,P0DP25,Q9GZY8,O15020,Q96QK1,O75150,Q14141 36 +Pole plasm 0.3662941044364982 0.1723515688863869 0.8631611447608554 1.0 1.0 5 Q9Y2W6 1 +F actin capping protein complex 0.3467275722816603 0.1695822061564514 0.8653387172758957 1.0 1.0 6 Q9BPX3,P35611 2 +Wash complex 0.4452338661930226 0.168992966969467 0.865802173382666 1.0 1.0 3 P52907,Q2M389 2 +Sodium potassium exchanging atpase complex 0.4339232567472304 0.1487147639325831 0.8817787108564861 1.0 1.0 3 P05023 1 +Cation transporting atpase complex 0.4339232567472304 0.1487147639325831 0.8817787108564861 1.0 1.0 3 P05023 1 +Early endosome membrane 0.3087405064492663 0.14701331444327 0.8831215111045645 1.0 1.0 52 Q9H223,Q9Y5X3,Q86YV9,Q4V328,Q9HC07,O14964,Q15075,Q9UNH7,Q9UJY4,Q15276,Q5T9L3 11 +Tight junction 0.3036116185717967 0.1467807792994648 0.883305056246753 1.0 1.0 32 Q12959,Q9UDY2,Q9Y4G8,Q8NI35,Q9NR77,O43815,P25054,Q9P2M7,Q92974,Q16625,Q8N3R9,P55196,Q86UE4,P11802 14 +Dopaminergic synapse 0.4313203078744865 0.144288510837567 0.8852726503956077 1.0 1.0 3 O75955,P41440 2 +Neuron projection cytoplasm 0.3049687524279363 0.1396764912114448 0.8889156015923458 1.0 1.0 35 P07196,Q00577,P33176,O60333,Q9Y2T2,Q9UQB8,O60313,P23246,Q14168 9 +Vcp npl4 ufd1 aaa atpase complex 0.3304682868998246 0.1280342778170506 0.898121846493763 1.0 1.0 7 Q96CS3,O94888,Q04323,Q8TAT6,Q92890,Q9UNN5 6 +U6 snrnp 0.3461298665020812 0.1242511543330165 0.901116420705352 1.0 1.0 5 P62310,Q9UK45 2 +Phospholipid translocating atpase complex 0.5362533293873997 0.1240436919758761 0.9012806809891576 1.0 1.0 2 Q9NV96 1 +Cul4 ring e3 ubiquitin ligase complex 0.3289026694752561 0.123653532674023 0.901589604751837 1.0 1.0 7 Q92990 1 +Presynaptic active zone 0.3045157456922328 0.1215938288573172 0.9032207010819208 1.0 1.0 15 P05067,P20020,Q8IUD2,P56545,P19022,Q13277,Q7L0J3,P35222,P27824,Q99623,O75955,Q07021,O60716,P41440 14 +Ruffle 0.2968436547099315 0.1173709570835327 0.906566097862452 1.0 1.0 63 Q9Y5X3,Q7L576,P53365,Q9BPX3,P12814,P31751,Q9UQB8,P25054,O00159,Q9BZG1,Q86YS7,P15311,P35579,P09493,P50570,Q10713,Q9UPN3,P21281 18 +Intrinsic component of presynaptic membrane 0.3621557595498867 0.116630598120579 0.9071527893973548 1.0 1.0 4 P20020,P27824,Q92542 3 +Intrinsic component of postsynaptic specialization membrane 0.3621557595498854 0.1166305981205765 0.9071527893973568 1.0 1.0 4 Q15334,Q15375,Q9BQT9 3 +Cell projection membrane 0.2856465421697285 0.1153729034133738 0.9081495554648088 1.0 1.0 71 P55011,P40855,P31751,O15144,Q9BZG1,Q86YS7,P50570,Q8WXH0,Q15019,O95721,P15311,P23396,Q01082,Q15286,P25054,O00159,P09493,Q9UPN3,Q14168 19 +Axonal growth cone 0.324346806052044 0.1097632261901265 0.9125971560218568 1.0 1.0 6 Q7L576 1 +Actin filament bundle 0.2948565129539069 0.104801485992453 0.9165333308932924 1.0 1.0 30 P06753,P35580,P35579,O43707,P09493,P12814,P67936 7 +Cohesin complex 0.3356042654028308 0.1019662327777854 0.9187834776860968 1.0 1.0 5 Q9UQE7,Q14683,Q8N3U4,Q8WVM7 4 +Nuclear exosome rnase complex 0.3081729880722067 0.10107396730272 0.9194917432794864 1.0 1.0 11 Q13868 1 +Endocytic vesicle lumen 0.3149629629629659 0.0876029378842925 0.9301922670652096 1.0 1.0 6 P07900,Q92598,O14964,P14625,Q9Y4L1 5 +Nuclear pore nuclear basket 0.3127649346724017 0.0835798819334503 0.9333904628508336 1.0 1.0 8 P12270,P41208 2 +Escrt iii complex 0.3120164375279529 0.0810098783089239 0.9354340965728012 1.0 1.0 6 O43633 1 +Multivesicular body membrane 0.311465787496861 0.0800946329711616 0.9361619913040236 1.0 1.0 8 O43633,Q8WUX9 2 +Mitochondrial large ribosomal subunit 0.2944963813966372 0.0785809466610449 0.9373659430293024 1.0 1.0 34 Q7Z7F7,Q567V2 2 +Sin3 complex 0.3207938388625451 0.0739474262599571 0.9410522184231148 1.0 1.0 5 O75182,Q96ST3,Q9UBU8,Q92769 4 +Meiotic cohesin complex 0.3355048859934721 0.0738925575626113 0.9410958778652988 1.0 1.0 4 Q9UQE7,Q8N3U4,Q14683 3 +Sperm principal piece 0.4865344776561191 0.0717375943732216 0.9428107372385692 1.0 1.0 2 Q9BW83 1 +Autophagosome 0.2892556105716559 0.0717065708711246 0.9428354268278496 1.0 1.0 30 O43633,Q13501,O95721,Q8TBX8,Q8WUX9,P19474,P42858,Q9UMX0,Q969Q5 9 +Sarcolemma 0.2848287567768178 0.0679656334871133 0.9458129915049662 1.0 1.0 27 O75298,P05023,Q08209,Q96QD8,Q9H9S5 5 +Integral component of presynaptic active zone membrane 0.3620485494375367 0.0584515264799801 0.9533889727009156 1.0 1.0 3 P27824,P20020 2 +Intrinsic component of presynaptic active zone membrane 0.3620485494375367 0.0584515264799801 0.9533889727009156 1.0 1.0 3 P27824,P20020 2 +Anchored component of plasma membrane 0.3602723505032581 0.0570044747901879 0.9545416305725708 1.0 1.0 3 Q9NQX3,Q15334 2 +Microbody lumen 0.2762598158931661 0.0540060315732363 0.9569303587563516 1.0 1.0 23 Q15067,O15254,Q13011 3 +Cd95 death inducing signaling complex 0.4477656111275599 0.0474131932562304 0.962183914148526 1.0 1.0 2 Q9UNN5 1 +Death inducing signaling complex 0.4477656111275599 0.0474131932562304 0.962183914148526 1.0 1.0 2 Q9UNN5 1 +Sperm connecting piece 0.4451021012133825 0.0461751416799577 0.9631706554013936 1.0 1.0 2 P10644 1 +Cytoplasmic microtubule 0.2712369705407084 0.0457550224478449 0.963505508124488 1.0 1.0 21 Q9H6U6,P25054,Q9Y5M8,Q9BSJ2 4 +Podosome 0.2869857252819552 0.0441010250479033 0.9648238757112098 1.0 1.0 12 P67936 1 +Rna polymerase iii complex 0.2918518518518549 0.0406148305966717 0.9676029608061604 1.0 1.0 6 O14802,O15160,Q9BUI4,P19388,Q9H1D9 5 +Specific granule 0.2931520604883947 0.0405802264994446 0.9676305481375482 1.0 1.0 41 Q13813,Q8WVQ1,O00264,P30519,Q13277,Q4KMQ2,Q7L576,Q9Y5K8,Q07065 9 +Exocytic vesicle 0.2946022179448972 0.0393938987563366 0.968576344222562 1.0 1.0 46 P09496,Q15019,O00429,O43752,Q9BVK6,O15400,O60333,Q13277,Q15286,O43760,O76024,Q9GZY8,P0DP25,P61421,Q14141,Q92905,O15126,Q9BT78 18 +Kinesin complex 0.272158557921929 0.0350346410368466 0.972052118266804 1.0 1.0 19 Q15058,O60333,Q9H0B6,P33176 4 +Transcription factor tfiih holo complex 0.3250444049733557 0.0347324845294622 0.972293057638373 1.0 1.0 3 P18074,P19447 2 +Basal dendrite 0.4033737792246293 0.0323948543248912 0.974157165989928 1.0 1.0 2 O15498 1 +Non motile cilium 0.281248283512241 0.0317125199493312 0.9747013104335543 1.0 1.0 16 Q15019,Q9BV73,Q15555,Q15154,P41208 5 +Axon initial segment 0.383841373187341 0.0287789373967845 0.9770408994439368 1.0 1.0 2 P78559 1 +Node of ranvier 0.3838413731873406 0.0287789373967845 0.9770408994439368 1.0 1.0 2 Q12959 1 +Exoribonuclease complex 0.2815572895316031 0.0264987419307226 0.9788595370418174 1.0 1.0 15 Q13868,O00178 2 +Ap 3 adaptor complex 0.2992895204262815 0.0249264660770169 0.9801136169132224 1.0 1.0 3 O14617,Q92572 2 +Presynaptic endocytic zone 0.3444806155667435 0.0248704879344409 0.9801582671666664 1.0 1.0 2 P09496 1 +Photoreceptor ribbon synapse 0.3160698431488687 0.023711813327959 0.9810824829828696 1.0 1.0 2 P11142 1 +Hops complex 0.2992009470257558 0.0233707433560431 0.981354542049401 1.0 1.0 2 Q96AX1 1 +Amphisome membrane 0.2815614906877854 0.0157960519513373 0.9873970981312844 1.0 1.0 7 O43633 1 +Distal axon 0.2834250147996928 0.012844220889997 0.989752076230618 1.0 1.0 64 O75150,P50570,P51116,Q06787,Q13561,O75312,Q9UKA9,Q13277,P11142,Q7L576,O00213,Q99720,Q8TAG9,P07196,Q96A65,Q7Z406,Q8IXJ6,P0DP25,Q02790,Q5T1M5,Q14141 21 +Gpi anchor transamidase complex 0.2540716612377814 0.0044082915755512 0.9964827036043112 1.0 1.0 4 Q92643,Q96S52,O43292 3 diff --git a/msigdb_gocc/selections.json b/msigdb_gocc/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..825c61e221f72712b2ac3d5b72a25ab3c470d221 --- /dev/null +++ b/msigdb_gocc/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["90s preribosome", "9plus0 non motile cilium", "9plus2 motile cilium", "A band", "Acrosomal membrane", "Acrosomal vesicle", "Actin based cell projection", "Actin cytoskeleton", "Actin filament", "Actin filament bundle", "Actomyosin", "Adherens junction", "Aggresome", "Alpha dna polymerase primase complex", "Alveolar lamellar body", "Aminoacyl trna synthetase multienzyme complex", "Ampa glutamate receptor complex", "Amphisome", "Amphisome membrane", "Anaphase promoting complex", "Anchored component of membrane", "Anchored component of plasma membrane", "Anchored component of postsynaptic membrane", "Anchored component of synaptic membrane", "Anchored component of synaptic vesicle membrane", "Anchoring junction", "Annulate lamellae", "Ap 1 adaptor complex", "Ap 3 adaptor complex", "Ap type membrane coat adaptor complex", "Apical dendrite", "Apical junction complex", "Apical part of cell", "Apical plasma membrane", "Apicolateral plasma membrane", "Arp2 3 protein complex", "Aryl hydrocarbon receptor complex", "Aster", "Astrocyte end foot", "Astrocyte projection", "Atac complex", "Atp binding cassette abc transporter complex", "Atpase complex", "Atpase dependent transmembrane transport complex", "Autolysosome", "Autophagosome", "Autophagosome membrane", "Axolemma", "Axon", "Axon cytoplasm", "Axon hillock", "Axon initial segment", "Axonal growth cone", "Azurophil granule", "Azurophil granule lumen", "Azurophil granule membrane", "B wich complex", "Barr body", "Basal cortex", "Basal dendrite", "Basal part of cell", "Basement membrane", "Basolateral plasma membrane", "Bcl 2 family protein complex", "Beta catenin destruction complex", "Beta catenin tcf complex", "Bleb", "Bloc complex", "Blood microparticle", "Box c d rnp complex", "Box h aca rnp complex", "Box h aca snornp complex", "Box h aca telomerase rnp complex", "Brca1 a complex", "Brca1 c complex", "Brisc complex", "Brush border", "Brush border membrane", "Cajal body", "Calcineurin complex", "Calcium and calmodulin dependent protein kinase complex", "Calcium channel complex", "Camp dependent protein kinase complex", "Carboxy terminal domain protein kinase complex", "Caspase complex", "Catalytic complex", "Catalytic step 1 spliceosome", "Catalytic step 2 spliceosome", "Catenin complex", "Cation channel complex", "Cation transporting atpase complex", "Catsper complex", "Caveola", "Ccaat binding factor complex", "Ccr4 not complex", "Ccr4 not core complex", "Cd40 receptor complex", "Cd95 death inducing signaling complex", "Cdc73 paf1 complex", "Cell body", "Cell body membrane", "Cell cell contact zone", "Cell cell junction", "Cell cortex", "Cell cortex region", "Cell division site", "Cell leading edge", "Cell pole", "Cell projection membrane", "Cell substrate junction", "Cell surface", "Cell tip", "Cell trailing edge", "Central element", "Centriolar satellite", "Centriolar subdistal appendage", "Centriole", "Centrosome", "Cerebellar mossy fiber", "Chaperone complex", "Chaperonin containing t complex", "Chitosome", "Chloride channel complex", "Cholinergic synapse", "Chromaffin granule", "Chromaffin granule membrane", "Chromatin", "Chromatin silencing complex", "Chromatoid body", "Chromocenter", "Chromosomal region", "Chromosome", "Chromosome centromeric core domain", "Chromosome centromeric region", "Chromosome passenger complex", "Chromosome telomeric region", "Chromosome telomeric repeat region", "Cia complex", "Ciliary basal body", "Ciliary base", "Ciliary membrane", "Ciliary plasm", "Ciliary rootlet", "Ciliary tip", "Ciliary transition zone", "Cilium", "Cis golgi network", "Cis golgi network membrane", "Clathrin adaptor complex", "Clathrin coat", "Clathrin coat of coated pit", "Clathrin coat of endocytic vesicle", "Clathrin coated endocytic vesicle", "Clathrin coated endocytic vesicle membrane", "Clathrin coated pit", "Clathrin coated vesicle", "Clathrin coated vesicle membrane", "Clathrin complex", "Clathrin sculpted gamma aminobutyric acid transport vesicle", "Clathrin sculpted vesicle", "Clathrin vesicle coat", "Cleavage furrow", "Cluster of actin based cell projections", "Coated vesicle", "Coated vesicle membrane", "Cohesin complex", "Collagen containing extracellular matrix", "Collagen trimer", "Commitment complex", "Compact myelin", "Condensed chromosome", "Condensed chromosome centromeric region", "Condensed nuclear chromosome", "Condensin complex", "Contractile fiber", "Contractile ring", "Cop9 signalosome", "Copi coated vesicle", "Copi coated vesicle membrane", "Copi vesicle coat", "Copii coated er to golgi transport vesicle", "Copii vesicle coat", "Core mediator complex", "Cornified envelope", "Cortical actin cytoskeleton", "Cortical cytoskeleton", "Cortical endoplasmic reticulum", "Cortical granule", "Costamere", "Crd mediated mrna stability complex", "Ctf18 rfc like complex", "Cul2 ring ubiquitin ligase complex", "Cul3 ring ubiquitin ligase complex", "Cul4 ring e3 ubiquitin ligase complex", "Cul4a ring e3 ubiquitin ligase complex", "Cul4b ring e3 ubiquitin ligase complex", "Cul5 ring ubiquitin ligase complex", "Cullin ring ubiquitin ligase complex", "Cuticular plate", "Cyclin a2 cdk2 complex", "Cyclin cdk positive transcription elongation factor complex", "Cyclin dependent protein kinase holoenzyme complex", "Cytochrome complex", "Cytolytic granule", "Cytoplasmic dynein complex", "Cytoplasmic exosome rnase complex", "Cytoplasmic microtubule", "Cytoplasmic region", "Cytoplasmic side of endoplasmic reticulum membrane", "Cytoplasmic side of endosome membrane", "Cytoplasmic side of lysosomal membrane", "Cytoplasmic side of membrane", "Cytoplasmic stress granule", "Cytoplasmic ubiquitin ligase complex", "Cytoskeleton of presynaptic active zone", "Cytosolic large ribosomal subunit", "Cytosolic region", "Cytosolic ribosome", "Cytosolic small ribosomal subunit", "Death inducing signaling complex", "Dendrite cytoplasm", "Dendrite membrane", "Dendrite terminus", "Dendritic growth cone", "Dendritic shaft", "Dendritic spine head", "Dendritic spine membrane", "Dendritic tree", "Dense body", "Dense core granule", "Dense core granule membrane", "Dentate gyrus mossy fiber", "Derlin 1 retrotranslocation complex", "Desmosome", "Deuterosome", "Dihydrolipoyl dehydrogenase complex", "Distal axon", "Dna packaging complex", "Dna polymerase complex", "Dna repair complex", "Dna replication factor c complex", "Dna replication preinitiation complex", "Dopaminergic synapse", "Dynactin complex", "Dynein axonemal particle", "Dynein complex", "Dystrophin associated glycoprotein complex", "Early endosome", "Early endosome lumen", "Early endosome membrane", "Early phagosome", "Ekc keops complex", "Elongator holoenzyme complex", "Elongin complex", "Emc complex", "Endocytic vesicle", "Endocytic vesicle lumen", "Endocytic vesicle membrane", "Endolysosome", "Endolysosome lumen", "Endolysosome membrane", "Endopeptidase complex", "Endoplasmic reticulum", "Endoplasmic reticulum chaperone complex", "Endoplasmic reticulum exit site", "Endoplasmic reticulum golgi intermediate compartment", "Endoplasmic reticulum golgi intermediate compartment membrane", "Endoplasmic reticulum lumen", "Endoplasmic reticulum palmitoyltransferase complex", "Endoplasmic reticulum plasma membrane contact site", "Endoplasmic reticulum protein containing complex", "Endoplasmic reticulum quality control compartment", "Endoplasmic reticulum tubular network", "Endoplasmic reticulum tubular network membrane", "Endoribonuclease complex", "Endosome", "Endosome lumen", "Endosome membrane", "Envelope", "Enzyme activator complex", "Epsilon dna polymerase complex", "Equatorial microtubule organizing center", "Er membrane insertion complex", "Er to golgi transport vesicle membrane", "Er ubiquitin ligase complex", "Esc e z complex", "Escrt complex", "Escrt i complex", "Escrt iii complex", "Euchromatin", "Eukaryotic translation initiation factor 2 complex", "Eukaryotic translation initiation factor 2b complex", "Eukaryotic translation initiation factor 3 complex", "Eukaryotic translation initiation factor 3 complex eif3m", "Eukaryotic translation initiation factor 4f complex", "Excitatory synapse", "Exocyst", "Exocytic vesicle", "Exon exon junction complex", "Exoribonuclease complex", "External encapsulating structure", "External side of apical plasma membrane", "External side of plasma membrane", "Extrinsic component of cytoplasmic side of plasma membrane", "Extrinsic component of endoplasmic reticulum membrane", "Extrinsic component of endosome membrane", "Extrinsic component of external side of plasma membrane", "Extrinsic component of membrane", "Extrinsic component of mitochondrial inner membrane", "Extrinsic component of organelle membrane", "Extrinsic component of plasma membrane", "Extrinsic component of postsynaptic membrane", "Extrinsic component of postsynaptic specialization membrane", "Extrinsic component of synaptic membrane", "F actin capping protein complex", "Fascia adherens", "Female germ cell nucleus", "Female pronucleus", "Fhf complex", "Fibrillar center", "Ficolin 1 rich granule", "Ficolin 1 rich granule lumen", "Ficolin 1 rich granule membrane", "Filamentous actin", "Filopodium", "Filopodium membrane", "Filopodium tip", "Filtration diaphragm", "Flemming body", "Flotillin complex", "Gaba ergic synapse", "Gamma secretase complex", "Gamma tubulin complex", "Gamma tubulin large complex", "Gap junction", "Gator2 complex", "Gemini of coiled bodies", "Germ cell nucleus", "Gid complex", "Glial cell projection", "Glutamatergic synapse", "Glycinergic synapse", "Glycogen granule", "Glycoprotein complex", "Golgi apparatus", "Golgi apparatus subcompartment", "Golgi associated vesicle", "Golgi associated vesicle membrane", "Golgi cis cisterna", "Golgi cisterna", "Golgi cisterna membrane", "Golgi lumen", "Golgi medial cisterna", "Golgi membrane", "Golgi stack", "Golgi trans cisterna", "Golgi transport complex", "Gpi anchor transamidase complex", "Granular component", "Growth cone membrane", "Gtpase complex", "Guanyl nucleotide exchange factor complex", "H3 histone acetyltransferase complex", "H4 h2a histone acetyltransferase complex", "H4 histone acetyltransferase complex", "Haus complex", "Hemidesmosome", "Hemoglobin complex", "Heterochromatin", "Hfe transferrin receptor complex", "High density lipoprotein particle", "Hippocampal mossy fiber", "Hippocampal mossy fiber to ca3 synapse", "Histone deacetylase complex", "Histone methyltransferase complex", "Histone pre mrna 3 end processing complex", "Hops complex", "Host cellular component", "Hrd1p ubiquitin ligase erad l complex", "Hulc complex", "I band", "Ikappab kinase complex", "Immunological synapse", "Inclusion body", "Inflammasome complex", "Inhibitory synapse", "Inner mitochondrial membrane protein complex", "Ino80 complex", "Ino80 type complex", "Insulin responsive compartment", "Integral component of cytoplasmic side of endoplasmic reticulum membrane", "Integral component of lysosomal membrane", "Integral component of presynaptic active zone membrane", "Integral component of synaptic vesicle membrane", "Integrator complex", "Integrin complex", "Intercalated disc", "Intercellular bridge", "Intercellular canaliculus", "Intermediate filament", "Intermediate filament cytoskeleton", "Intracellular protein containing complex", "Intraciliary transport particle", "Intraciliary transport particle a", "Intraciliary transport particle b", "Intrinsic component of endoplasmic reticulum membrane", "Intrinsic component of external side of plasma membrane", "Intrinsic component of golgi membrane", "Intrinsic component of mitochondrial inner membrane", "Intrinsic component of mitochondrial membrane", "Intrinsic component of mitochondrial outer membrane", "Intrinsic component of nuclear inner membrane", "Intrinsic component of organelle membrane", "Intrinsic component of peroxisomal membrane", "Intrinsic component of plasma membrane", "Intrinsic component of postsynaptic density membrane", "Intrinsic component of postsynaptic membrane", "Intrinsic component of postsynaptic specialization membrane", "Intrinsic component of presynaptic active zone membrane", "Intrinsic component of presynaptic membrane", "Intrinsic component of synaptic membrane", "Intrinsic component of synaptic vesicle membrane", "Intrinsic component of vacuolar membrane", "Ion channel complex", "Iron sulfur cluster assembly complex", "Iswi type complex", "Juxtaparanode region of axon", "Keratin filament", "Kinesin complex", "Kinetochore microtubule", "Lamellar body", "Lamellipodium", "Lamellipodium membrane", "Lamin filament", "Laminin complex", "Large ribosomal subunit", "Late endosome", "Late endosome membrane", "Lateral element", "Lateral part of cell", "Lateral plasma membrane", "Leading edge membrane", "Lewy body", "Lipid droplet", "Lipopolysaccharide receptor complex", "Low density lipoprotein particle", "Lsm1 7 pat1 complex", "Lsm2 8 complex", "Lumenal side of endoplasmic reticulum membrane", "Lumenal side of membrane", "Lysosomal lumen", "M band", "Magnesium dependent protein serine threonine phosphatase complex", "Main axon", "Male germ cell nucleus", "Male pronucleus", "Manchette", "Mcm complex", "Mcrd mediated mrna stability complex", "Mediator complex", "Meiotic cohesin complex", "Meiotic spindle", "Membrane coat", "Membrane microdomain", "Membrane protein complex", "Messenger ribonucleoprotein complex", "Methylosome", "Methyltransferase complex", "Mhc class i peptide loading complex", "Mhc class i protein complex", "Mhc protein complex", "Mib complex", "Micos complex", "Microbody", "Microbody lumen", "Microbody membrane", "Microfibril", "Microtubule", "Microtubule associated complex", "Microtubule bundle", "Microtubule cytoskeleton", "Microtubule end", "Microtubule minus end", "Microtubule organizing center", "Microtubule organizing center attachment site", "Microtubule plus end", "Microvillus", "Microvillus membrane", "Midbody", "Mismatch repair complex", "Mitochondria associated endoplasmic reticulum membrane", "Mitochondrial alpha ketoglutarate dehydrogenase complex", "Mitochondrial crista", "Mitochondrial envelope", "Mitochondrial intermembrane space protein transporter complex", "Mitochondrial large ribosomal subunit", "Mitochondrial matrix", "Mitochondrial permeability transition pore complex", "Mitochondrial protein containing complex", "Mitochondrial proton transporting atp synthase complex coupling factor f o", "Mitochondrial pyruvate dehydrogenase complex", "Mitochondrial small ribosomal subunit", "Mitochondrial tricarboxylic acid cycle enzyme complex", "Mitochondrion", "Mitotic cohesin complex", "Mitotic spindle", "Mitotic spindle astral microtubule", "Mitotic spindle microtubule", "Mitotic spindle midzone", "Mitotic spindle pole", "Mll1 2 complex", "Mll3 4 complex", "Mmxd complex", "Motile cilium", "Mpp7 dlg1 lin7 complex", "Mrna cleavage and polyadenylation specificity factor complex", "Mrna cleavage factor complex", "Mrna editing complex", "Multimeric ribonuclease p complex", "Multivesicular body", "Multivesicular body membrane", "Myelin sheath", "Myelin sheath abaxonal region", "Myelin sheath adaxonal region", "Myofilament", "Myosin complex", "Myosin filament", "Myosin ii complex", "N terminal protein acetyltransferase complex", "Nadh dehydrogenase complex", "Nascent polypeptide associated complex", "Nata complex", "Nbaf complex", "Neurofibrillary tangle", "Neurofilament", "Neuromuscular junction", "Neuron projection", "Neuron projection cytoplasm", "Neuron projection membrane", "Neuron projection terminus", "Neuron spine", "Neuron to neuron synapse", "Neuronal dense core vesicle", "Neuronal dense core vesicle membrane", "Neuronal ribonucleoprotein granule", "Neurotransmitter receptor complex", "Nlrp3 inflammasome complex", "Nls dependent protein nuclear import complex", "Node of ranvier", "Non motile cilium", "Nonhomologous end joining complex", "Npbaf complex", "Nsl complex", "Nuclear body", "Nuclear chromosome", "Nuclear cyclin dependent protein kinase holoenzyme complex", "Nuclear envelope", "Nuclear envelope lumen", "Nuclear exosome rnase complex", "Nuclear inclusion body", "Nuclear inner membrane", "Nuclear lamina", "Nuclear membrane", "Nuclear outer membrane", "Nuclear outer membrane endoplasmic reticulum membrane network", "Nuclear periphery", "Nuclear pore", "Nuclear pore central transport channel", "Nuclear pore nuclear basket", "Nuclear pore outer ring", "Nuclear protein containing complex", "Nuclear replication fork", "Nuclear rna export factor complex", "Nuclear speck", "Nuclear stress granule", "Nuclear ubiquitin ligase complex", "Nucleocytoplasmic transport complex", "Nucleoid", "Nucleolar ribonuclease p complex", "Nucleolus", "Nucleotide activated protein kinase complex", "Nucleotide excision repair complex", "Nurd complex", "Nurf complex", "Oligosaccharyltransferase complex", "Organellar ribosome", "Organelle envelope lumen", "Organelle inner membrane", "Organelle membrane contact site", "Organelle subcompartment", "Origin recognition complex", "Outer dense fiber", "Outer kinetochore", "Outer membrane", "Outer mitochondrial membrane protein complex", "Oxidoreductase complex", "Oxoglutarate dehydrogenase complex", "P body", "Palmitoyltransferase complex", "Pam complex tim23 associated import motor", "Parallel fiber to purkinje cell synapse", "Paranodal junction", "Paranode region of axon", "Paraspeckles", "Pcg protein complex", "Peptidase complex", "Peptidase inhibitor complex", "Pericentric heterochromatin", "Pericentriolar material", "Periciliary membrane compartment", "Perikaryon", "Perinuclear endoplasmic reticulum", "Perinuclear region of cytoplasm", "Perinucleolar compartment", "Phagocytic cup", "Phagocytic vesicle", "Phagocytic vesicle lumen", "Phagocytic vesicle membrane", "Phagolysosome", "Phagophore assembly site", "Phagophore assembly site membrane", "Phosphatase complex", "Phosphatidylinositol 3 kinase complex", "Phosphatidylinositol 3 kinase complex class iii", "Phospholipid translocating atpase complex", "Photoreceptor connecting cilium", "Photoreceptor inner segment", "Photoreceptor outer segment", "Photoreceptor ribbon synapse", "Pi body", "Picln sm protein complex", "Pigment granule", "Pinosome", "Pip body", "Plasma membrane protein complex", "Plasma membrane raft", "Plasma membrane region", "Plasma membrane signaling receptor complex", "Platelet alpha granule", "Platelet alpha granule lumen", "Platelet alpha granule membrane", "Platelet dense granule", "Platelet dense granule lumen", "Platelet dense granule membrane", "Platelet dense tubular network", "Platelet dense tubular network membrane", "Pml body", "Podosome", "Polar microtubule", "Pole plasm", "Polymeric cytoskeletal fiber", "Polysomal ribosome", "Polysome", "Pore complex", "Post mrna release spliceosomal complex", "Postsynapse", "Postsynaptic cytoskeleton", "Postsynaptic cytosol", "Postsynaptic density intracellular component", "Postsynaptic density membrane", "Postsynaptic endocytic zone", "Postsynaptic endosome", "Postsynaptic membrane", "Postsynaptic recycling endosome", "Postsynaptic specialization intracellular component", "Postsynaptic specialization membrane", "Potassium channel complex", "Prc1 complex", "Pre snornp complex", "Precatalytic spliceosome", "Prefoldin complex", "Preribosome", "Preribosome large subunit precursor", "Preribosome small subunit precursor", "Prespliceosome", "Presynapse", "Presynaptic active zone", "Presynaptic active zone cytoplasmic component", "Presynaptic active zone membrane", "Presynaptic cytoskeleton", "Presynaptic cytosol", "Presynaptic endocytic zone", "Presynaptic membrane", "Procentriole replication complex", "Pronucleus", "Protease inhibitor complex", "Proteasome accessory complex", "Proteasome complex", "Proteasome core complex", "Proteasome core complex alpha subunit complex", "Proteasome core complex beta subunit complex", "Proteasome regulatory particle", "Proteasome regulatory particle base subcomplex", "Proteasome regulatory particle lid subcomplex", "Protein acetyltransferase complex", "Protein complex involved in cell adhesion", "Protein dna complex", "Protein kinase complex", "Protein lipid complex", "Protein phosphatase 4 complex", "Protein phosphatase type 1 complex", "Protein phosphatase type 2a complex", "Proton transporting atp synthase complex", "Proton transporting atp synthase complex catalytic core f 1", "Proton transporting atp synthase complex coupling factor f o", "Proton transporting two sector atpase complex", "Proton transporting two sector atpase complex catalytic domain", "Proton transporting two sector atpase complex proton transporting domain", "Proton transporting v type atpase complex", "Proton transporting v type atpase v0 domain", "Proton transporting v type atpase v1 domain", "Proximal dendrite", "Prp19 complex", "Pseudopodium", "Ptw pp1 phosphatase complex", "Pwp2p containing subcomplex of 90s preribosome", "R2tp complex", "Ragulator complex", "Rdna heterochromatin", "Receptor complex", "Recycling endosome", "Recycling endosome membrane", "Replication fork", "Replisome", "Respirasome", "Respiratory chain complex iii", "Respiratory chain complex iv", "Retromer complex", "Ribbon synapse", "Ribonuclease mrp complex", "Ribonuclease p complex", "Ribonucleoprotein complex", "Ribonucleoprotein granule", "Ribose phosphate diphosphokinase complex", "Ribosomal subunit", "Ribosome", "Risc loading complex", "Rna cap binding complex", "Rna polymerase complex", "Rna polymerase i complex", "Rna polymerase ii core complex", "Rna polymerase ii holoenzyme", "Rna polymerase ii transcription regulator complex", "Rna polymerase ii transcription repressor complex", "Rna polymerase iii complex", "Rna polymerase iii transcription regulator complex", "Rnai effector complex", "Rough endoplasmic reticulum", "Rough endoplasmic reticulum membrane", "Rpap3 r2tp prefoldin like complex", "Ruffle", "Ruffle membrane", "Saga complex", "Saga type complex", "Sarcolemma", "Sarcoplasm", "Sarcoplasmic reticulum lumen", "Sarcoplasmic reticulum membrane", "Scar complex", "Scf ubiquitin ligase complex", "Schaffer collateral ca1 synapse", "Schmidt lanterman incisure", "Sec61 translocon complex", "Secondary lysosome", "Secretory granule", "Secretory granule membrane", "Secretory vesicle", "Seh1 associated complex", "Semaphorin receptor complex", "Septin cytoskeleton", "Serine protease inhibitor complex", "Serine type endopeptidase complex", "Serine type peptidase complex", "Set1c compass complex", "Sex chromatin", "Sex chromosome", "Shelterin complex", "Side of membrane", "Signal peptidase complex", "Signal recognition particle", "Sin3 complex", "Sin3 type complex", "Site of dna damage", "Site of double strand break", "Site of polarized growth", "Sm like protein family complex", "Small ribosomal subunit", "Small subunit processome", "Smc5 smc6 complex", "Smn complex", "Smn sm protein complex", "Smooth endoplasmic reticulum", "Smooth endoplasmic reticulum membrane", "Snare complex", "Sno s rna containing ribonucleoprotein complex", "Sodium potassium exchanging atpase complex", "Somatodendritic compartment", "Sorting endosome", "Spanning component of membrane", "Specific granule", "Specific granule lumen", "Specific granule membrane", "Spectrin", "Spectrin associated cytoskeleton", "Sperm annulus", "Sperm connecting piece", "Sperm fibrous sheath", "Sperm head", "Sperm head plasma membrane", "Sperm midpiece", "Sperm plasma membrane", "Sperm principal piece", "Spermatoproteasome complex", "Spherical high density lipoprotein particle", "Spindle", "Spindle microtubule", "Spindle midzone", "Spindle pole", "Spindle pole centrosome", "Spliceosomal complex", "Spliceosomal snrnp complex", "Spliceosomal tri snrnp complex", "Stereocilia coupling link", "Stereocilium bundle", "Stereocilium membrane", "Striated muscle thin filament", "Sumo ligase complex", "Supramolecular complex", "Supramolecular polymer", "Swi snf complex", "Swr1 complex", "Synapse", "Synaptic cleft", "Synaptic membrane", "Synaptic vesicle membrane", "Synaptonemal structure", "T tubule", "Telomerase holoenzyme complex", "Terminal bouton", "Tertiary granule", "Tertiary granule lumen", "Tertiary granule membrane", "Tetraspanin enriched microdomain", "Tho complex", "Tight junction", "Tim22 mitochondrial import inner membrane insertion complex", "Tim23 mitochondrial import inner membrane translocase complex", "Tor complex", "Torc1 complex", "Trans golgi network", "Trans golgi network membrane", "Trans golgi network transport vesicle", "Trans golgi network transport vesicle membrane", "Transcription elongation factor complex", "Transcription export complex", "Transcription export complex 2", "Transcription factor tfiid complex", "Transcription factor tfiih holo complex", "Transcription factor tfiiic complex", "Transcription factor tftc complex", "Transcription preinitiation complex", "Transcription regulator complex", "Transcription repressor complex", "Transferase complex", "Transferase complex transferring phosphorus containing groups", "Translation preinitiation complex", "Translocon complex", "Transport vesicle", "Transport vesicle membrane", "Transporter complex", "Trapp complex", "Tricarboxylic acid cycle enzyme complex", "Triglyceride rich plasma lipoprotein particle", "Trna methyltransferase complex", "Trna splicing ligase complex", "Tubular endosome", "U1 snrnp", "U12 type spliceosomal complex", "U2 snrnp", "U2 type catalytic step 2 spliceosome", "U2 type spliceosomal complex", "U2af complex", "U4 snrnp", "U5 snrnp", "U6 snrnp", "U7 snrnp", "Ubiquinone biosynthesis complex", "Ubiquitin conjugating enzyme complex", "Ubiquitin ligase complex", "Unconventional myosin complex", "Uniplex complex", "Vacuolar lumen", "Vacuolar membrane", "Vacuolar proton transporting v type atpase v0 domain", "Vacuole", "Varicosity", "Vcp npl4 ufd1 aaa atpase complex", "Vesicle coat", "Vesicle lumen", "Vesicle membrane", "Vesicle tethering complex", "Voltage gated calcium channel complex", "Wash complex", "Weibel palade body", "Wnt signalosome", "X chromosome", "Xy body", "Zona pellucida receptor complex", "Zonula adherens", "Zymogen granule", "Zymogen granule membrane"], "available_proteins": ["AAAS", "AAR2", "AARS", "AARS2", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD6", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ADA", "ADAM17", "ADAM9", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR7A2", "AKT1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG2", "ALG5", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APBB1", "APC", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOBEC3C", "APOL2", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP17", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARL8B", "ARMC1", "ARMC10", "ARMC8", "ARMCX3", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARVCF", "ASAH1", "ASCC2", "ASCC3", "ASNA1", "ASPH", "ASPSCR1", "ATAD1", "ATAD3A", "ATAD3B", "ATAD5", "ATG9A", "ATL2", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPAF2", "ATPIF1", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKB", "B4GAT1", "BABAM1", "BABAM2", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAP18", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BDH2", "BICD2", "BIRC6", "BLM", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPTF", "BRCA1", "BRD2", "BRD3", "BRD4", "BRD8", "BRI3BP", "BRIX1", "BSG", "BTF3", "BTRC", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "C12orf43", "C12orf73", "C14orf2", "C19orf70", "C1D", "C1QBP", "C1orf35", "C2CD2L", "C2CD5", "C3orf58", "C8orf59", "CAB39", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAMLG", "CAND1", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN7", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARS2", "CASK", "CAST", "CBL", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC22", "CCDC47", "CCDC58", "CCDC8", "CCDC86", "CCDC93", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC20", "CDC23", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC6", "CDC73", "CDCA2", "CDCA5", "CDCA7L", "CDCA8", "CDH2", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDKN2AIP", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPV", "CEP135", "CEP170", "CEP250", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CGN", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD3", "CHD4", "CHD8", "CHEK2", "CHERP", "CHID1", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHP1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIRBP", "CISD1", "CISD2", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLSTN3", "CLTA", "CLTC", "CLU", "CMPK1", "CNN2", "CNN3", "CNNM4", "CNOT1", "CNOT10", "CNOT11", "CNOT2", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COG3", "COG7", "COIL", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "COQ8B", "COQ9", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CREB1", "CREG1", "CRKL", "CRNKL1", "CRTAP", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CTBP1", "CTBP2", "CTCF", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CWC15", "CWC22", "CWF19L1", "CXorf57", "CYB5B", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCP1A", "DCP2", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DECR1", "DEK", "DENND4C", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHRS4", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA3", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNTTIP2", "DOCK7", "DOLPP1", "DPF2", "DPM1", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUSP3", "DUT", "DVL2", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFHD1", "EFL1", "EFTUD2", "EGFR", "EHD1", "EHD4", "EHHADH", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5A", "EIF6", "ELAC2", "ELAVL1", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENO1", "ENO2", "ENPP1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPDR1", "EPHA7", "EPHX1", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EZH2", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAHD1", "FAM129B", "FAM162A", "FAM208A", "FAM210B", "FAM3C", "FAM49B", "FAM8A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD5", "FBL", "FDFT1", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP4", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNBP1L", "FNBP4", "FNDC3A", "FOXK1", "FOXK2", "FOXRED1", "FSCN1", "FSTL1", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FUNDC2", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GGA1", "GGA2", "GGCX", "GGH", "GHDC", "GHITM", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLUD1", "GLYR1", "GM2A", "GNA13", "GNAI2", "GNAI3", "GNB1L", "GNG12", "GNG5", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNS", "GOLGA2", "GOLGA3", "GOLGA4", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLPH3L", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPD2", "GPHN", "GPI", "GPKOW", "GPR107", "GPR108", "GPR89B", "GPS1", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSK3B", "GSR", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS4", "HAUS5", "HAUS6", "HAX1", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HECTD3", "HELLS", "HELZ", "HERC2", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HINT2", "HIRA", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGN1", "HMGN3", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HOOK2", "HOXD13", "HP1BP3", "HPS3", "HPS6", "HPSE", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IFT52", "IGF2BP1", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBIP", "ILF2", "ILF3", "ILK", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPAD1", "IMPDH2", "INA", "INCENP", "INF2", "INTS1", "INTS11", "INTS12", "INTS13", "INTS14", "INTS3", "INTS4", "INTS7", "INTS9", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "ISCU", "ISOC1", "IST1", "ISY1", "ITCH", "ITGB1", "ITM2B", "ITM2C", "ITPRIP", "IVD", "JAGN1", "JMJD6", "JUP", "KARS", "KAT7", "KCTD12", "KCTD5", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KDM5A", "KDSR", "KEAP1", "KHDRBS1", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1468", "KIF11", "KIF14", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KNOP1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAMTOR3", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LPGAT1", "LRBA", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRRC59", "LRRC8C", "LRWD1", "LSG1", "LSM2", "LSM3", "LSM7", "LSM8", "LSS", "LTA4H", "LTV1", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LZTS2", "MACF1", "MAD2L1", "MAGED1", "MAGED2", "MAGT1", "MAK16", "MAN1A1", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP4", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARK2", "MARK3", "MARS", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBOAT7", "MCAM", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MEAF6", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED21", "MED23", "MED24", "MED25", "MED4", "MEN1", "MEPCE", "MESD", "METTL13", "METTL15", "MFAP1", "MFF", "MFN1", "MFSD10", "MGME1", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MIF", "MINDY3", "MINPP1", "MIOS", "MIPEP", "MKI67", "MLEC", "MMAB", "MMS19", "MMS22L", "MOB4", "MOGS", "MON2", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPDZ", "MPG", "MPHOSPH10", "MPHOSPH8", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRC2", "MRE11", "MRGBP", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL55", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTM1", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTX1", "MTX2", "MTX3", "MUT", "MXRA7", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO6", "NAA10", "NAA15", "NAA40", "NAA50", "NADK2", "NAGLU", "NAMPT", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCBP1", "NCBP3", "NCDN", "NCK1", "NCK2", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "NDC1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFC2", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NENF", "NES", "NEU1", "NF2", "NFRKB", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIPSNAP3A", "NISCH", "NKRF", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NME7", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NPC1", "NPC2", "NPLOC4", "NPM1", "NRBP1", "NRDC", "NRP1", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NT5C3A", "NTHL1", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDT1", "NUDT12", "NUDT21", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "OAT", "OCIAD1", "OCLN", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "ORC5", "OS9", "OSBP", "OSBPL11", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OXA1L", "OXSR1", "P3H1", "P3H3", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAIP1", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PAOX", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATJ", "PAWR", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH19", "PCID2", "PCK2", "PCM1", "PCNA", "PCNP", "PCYOX1", "PDAP1", "PDCD11", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE4DIP", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDP1", "PDPR", "PDS5A", "PDS5B", "PDSS2", "PDXK", "PDZD11", "PECR", "PEF1", "PELP1", "PES1", "PEX14", "PEX16", "PEX19", "PEX3", "PEX5", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGK1", "PGM1", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF14", "PHF5A", "PHF6", "PHF8", "PHIP", "PI4K2A", "PI4KA", "PI4KB", "PIBF1", "PICALM", "PIGK", "PIGL", "PIGS", "PIGT", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PKP2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPT1", "POFUT1", "POFUT2", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3F", "POLRMT", "POMGNT2", "PON2", "POP1", "POP4", "POR", "PPA2", "PPAN", "PPHLN1", "PPIB", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPM1F", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP1R9B", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPT1", "PPT2", "PRAF2", "PRC1", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PSAP", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN23", "PTPRF", "PTRH2", "PUM1", "PUM3", "PURA", "PUS1", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "PYM1", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABEP1", "RABGAP1", "RABGGTA", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "RECQL5", "REEP3", "REEP4", "REEP5", "REL", "REPS1", "RER1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RICTOR", "RIDA", "RIF1", "RILPL1", "RINT1", "RIOX1", "RIOX2", "RMDN1", "RMDN3", "RNASEH2A", "RNASET2", "RNF14", "RNF20", "RNF219", "RNF40", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS19BP1", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSU1", "RTCB", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "RXRB", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS2", "SART1", "SART3", "SASS6", "SATB2", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDCCAG3", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT8", "SEPT9", "SERAC1", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHC1", "SHCBP1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIN3A", "SIN3B", "SIRT1", "SIRT2", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC30A7", "SLC35A4", "SLC35B2", "SLC38A2", "SLC3A2", "SLC4A7", "SLC5A6", "SLC6A15", "SLC7A1", "SLFN11", "SLIRP", "SLK", "SLMAP", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SNAP23", "SNAP29", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG5", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPECC1", "SPECC1L", "SPEN", "SPNS1", "SPOUT1", "SPPL2A", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAU1", "STAU2", "STIP1", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX3", "STX5", "STX6", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACO1", "TAF15", "TAF4", "TAF7", "TAMM41", "TAP1", "TAP2", "TARDBP", "TARS2", "TBC1D10A", "TBCA", "TBCB", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCP1", "TDP2", "TDRKH", "TECR", "TELO2", "TENM3", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THADA", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM13", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TIMM9", "TIMMDC1", "TJP1", "TJP2", "TKT", "TLN1", "TM9SF2", "TM9SF4", "TMA16", "TMCO1", "TMED1", "TMED10", "TMED2", "TMED5", "TMED9", "TMEM109", "TMEM11", "TMEM126A", "TMEM14C", "TMEM165", "TMEM167A", "TMEM177", "TMEM192", "TMEM199", "TMEM201", "TMEM214", "TMEM30A", "TMEM33", "TMEM38B", "TMEM43", "TMEM59", "TMEM70", "TMEM97", "TMF1", "TMLHE", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOM1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOPBP1", "TOR1A", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TOX4", "TP53", "TP53BP1", "TP53BP2", "TPBG", "TPD52", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM28", "TRIP12", "TRIP13", "TRIT1", "TRMT10C", "TRMT112", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPO", "TSPYL1", "TSR1", "TST", "TTC1", "TTC19", "TTC21B", "TTC26", "TTC37", "TTC5", "TTF2", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWNK", "TXLNG", "TXNDC12", "TXNDC16", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UBA1", "UBA2", "UBA5", "UBAC1", "UBAP2", "UBAP2L", "UBE2G2", "UBE2K", "UBE2L3", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBLCP1", "UBP1", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UFD1", "UFL1", "UFSP2", "UGCG", "UGGT1", "UGT8", "UHRF1", "UNC119B", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "URB2", "USE1", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP28", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "UXS1", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VASP", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VPS13A", "VPS18", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS51", "VPS52", "VPS53", "VRK1", "VRK2", "VTA1", "WAPL", "WARS2", "WASF2", "WASHC4", "WBP11", "WBP2", 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0000000000000000000000000000000000000000..fddcaba863e79d83056dd9cd48deca15e6a469ca --- /dev/null +++ b/msigdb_gomf/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ee57b8aab41677e41d14a91c8152981aa5ae26fdc044b2fb8cc14a6fca1c9d71 +size 138628 diff --git a/msigdb_gomf/basic/plot_7.png b/msigdb_gomf/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..5c75b90cff87411492ff99d32915ad4d6aaade50 --- /dev/null +++ b/msigdb_gomf/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8d2c95645bbe3f59071ae6ea22fb9079f8a45795d9d4c282a5ca8e24d6ef2cd3 +size 143122 diff --git a/msigdb_gomf/basic/plot_8.png b/msigdb_gomf/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..e62789c3ae907d8ca25b02098f0542b657f778e0 --- /dev/null +++ b/msigdb_gomf/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:842a47b3e13b13b497f5f98c2e594c01c4a4fab275d296b04e28eba9ce80a07d +size 143847 diff --git a/msigdb_gomf/basic/plot_9.png b/msigdb_gomf/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..37a41307e4bfe685f8a0c9f10ed372ee02364421 --- /dev/null +++ b/msigdb_gomf/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a607ed1db8beddfc2ffb6f955c19d6bd036ab94537bb05aebe26fe7253ea4338 +size 140144 diff --git a/msigdb_gomf/consensus.joblib b/msigdb_gomf/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..445f380a52481285de720883bfaf6b013ae5a672 --- /dev/null +++ b/msigdb_gomf/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:115b23fbff3aab0d73bc25edaa5c47bb9cbb7968188b7c50846f9a6c832ca11f +size 121316 diff --git a/msigdb_gomf/df_merge.tsv b/msigdb_gomf/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..dcabd50380da4354c6adaf59e3dd044cc5560536 --- /dev/null +++ b/msigdb_gomf/df_merge.tsv @@ -0,0 +1,30 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Ion transmembrane transporter activity 37 102 3.961670222835864 7.442729181006413e-05 37.34466019417476 101.497572815534 2.0154097423383375 0.2561362875319209 17.172953606300336 11.579295798802024 2.277787478419462 0.3756175790939143 0.0014614768975583 0.0035005874053769 0.0029019850165452 0.0087569095928962 0.0011960075691188 +Tetrapyrrole binding 6 16 3.0888443122470632 0.0020093670724843 7.402912621359223 16.83252427184466 2.0044897428967667 0.1259264696495541 2.9589081005845346 2.0417036568087963 1.3464702305086589 0.2177422235164347 4.8043931388801744e-05 0.0021781449325651 0.0001612622666265 0.0018945002996002 0.0152442441513 +Inorganic molecular entity transmembrane transporter activity 28 77 3.014828681582503 0.0025712444644856 28.058252427184467 75.9635922330097 1.5031303400189615 0.2894264293069549 11.721339963426631 9.38477049228959 2.153051736566399 0.3821536813265525 0.0099808778063733 0.0059885984942463 0.0088198001136506 0.0156668580312851 0.00775992538362 +Cation transmembrane transporter activity 25 70 2.9830827269200832 0.0028536085170693 25.62135922330097 70.51699029126213 1.766742880952279 0.2698419237572138 12.29126021871486 8.422243011776631 2.00238274385689 0.3706372466673562 0.007466228697414 0.0007846366850434 0.0016782538909258 0.0256290540019712 0.0178256610000849 +Phosphatase regulator activity 7 23 2.8032627738990845 0.0050588433206784 5.890776699029126 21.42718446601942 0.2207502835350587 0.5696921397829399 3.3115291951500065 3.3518635354302604 0.8778999195679603 0.2968997706719961 0.0727446470735656 1.0 0.175896893635733 0.0430672573908121 0.0380095176885234 +Protein phosphatase regulator activity 5 20 2.765695843615377 0.005680148641058 5.211165048543689 18.79368932038835 0.2673383696568306 0.5750752516699464 3.016390758136069 2.679236773763369 0.8397594774518536 0.2970107094313646 0.0419634029481528 1.0 0.1226746045160812 0.0182889167317254 0.0328483629407697 +Protein transporter activity 5 15 2.698054080229297 0.0069746109152566 6.053398058252427 14.696601941747574 1.6882240898296943 0.1359359142649309 2.957968193176 1.443999336657768 1.4805047019217734 0.2345897542974644 0.0002230861935855 0.0002227197090729 8.694316847855437e-05 0.0028897230126965 0.0001398373652982 +Transporter activity 53 183 2.6759782717763656 0.007451147561549 62.22330097087379 172.27912621359224 2.173366592838491 0.2707201784543502 25.984753572620328 19.29276868436311 2.593156143256053 0.3916539604106395 0.0001909210368464 2.668183300994533e-05 0.0001188721116846 0.0018518439654433 5.482799358482696e-05 +Monooxygenase activity 4 9 2.5400798788686147 0.0110827153696235 4.043689320388349 8.322815533980583 1.6049222537693364 0.1501440468766332 1.612461779657682 1.2307404965531048 1.237349324058907 0.2369071661653372 1.6621846025872713e-05 0.0073558029266518 0.0021303683071518 0.0004258249435971 0.0089325963600969 +Endopeptidase activity 20 68 2.42264066923077 0.0154081590514074 19.08495145631068 62.800970873786405 1.5604938505680932 0.2935756148549138 5.629332570724372 6.156865220927466 1.27979578418692 0.359984229645684 0.0532466239831102 0.1896040470106967 0.2140877973077813 0.0002020221247156 5.476896119125089e-05 +Macromolecule transmembrane transporter activity 6 12 2.313036789868041 0.0207206165005331 4.820388349514563 12.281553398058252 1.6605285757306012 0.1306403746261988 2.4754663863133306 1.0160601209961664 1.3599823000893485 0.2280235038874096 0.0017607202845482 0.0001122733832082 0.0008717411361388 0.0119341177484456 0.0022722304352638 +Calcium ion binding 26 95 2.278555392109227 0.0226935081966945 21.00485436893204 81.67961165048544 0.6464856503310022 0.4940276647939897 7.408010340962093 8.52860815905726 1.2261945166831902 0.3858741960292539 0.1248717824987849 0.7414992917830734 0.2762030889389896 0.017858254198785 0.0010174707187199 +Protein transmembrane transporter activity 6 11 2.2777316887176213 0.0227425685025883 4.37621359223301 11.264563106796116 1.6409152716253632 0.1284874270119089 2.3258190399954897 0.995332092405782 1.387057072324357 0.2266762256512647 0.0010788177062325 6.765318543664244e-05 0.0005309775927247 0.0075105395483816 0.0010238181908857 +Proton transmembrane transporter activity 5 36 2.267748577719656 0.0233445352046817 12.769417475728156 35.478155339805824 1.2352045534927034 0.2879171268332734 5.319202861157036 2.7149368379617917 1.7021108079122016 0.3308025072902738 0.0002822552028569 2.6116330706367664e-05 7.389910731518841e-05 0.0090935958038613 0.0095202961329739 +Threonine type peptidase activity 5 8 2.235412009024267 0.0253903124290246 3.8106796116504857 8.762135922330097 1.392634148189787 0.2146040118876429 1.6274593113109357 0.6695334565847216 1.0340073360925757 0.2572219198248905 0.158700528988896 0.0652597674910206 0.1265462710440741 0.0042425564235442 2.7956915548836924e-05 +Threonine type endopeptidase activity 5 8 2.235412009024267 0.0253903124290246 3.7135922330097086 7.970873786407767 1.4913184573846054 0.1902243906475925 1.515457478026574 0.1681602725795027 1.0170822776023185 0.2455850375425174 0.1160984687124442 0.0470522829573702 0.0921025797166938 0.0015031185668187 2.312503759377148e-06 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen 9 35 2.2248169875939894 0.026093526522072 9.395631067961164 29.8373786407767 1.5709767518568172 0.2393367467664754 3.119976403291062 3.762391942431812 1.2135099906711824 0.3124947384976632 0.0056255680955388 0.0734458650364987 0.0601458293215769 0.0256436075985136 0.0148600283171556 +Anion channel activity 5 12 2.1764319167345594 0.0295229794054847 4.20873786407767 11.21116504854369 1.03959259790327 0.2192420598609839 2.3076742714116403 2.0905640066649145 1.3937691950814175 0.2662450395835827 1.0 1.0 1.0 0.4986229205358068 0.0451666412494461 +Fad binding 4 9 2.1751803109447447 0.0296166070236933 3.78883495145631 9.932038834951456 1.575439945642976 0.1698004033102896 1.8828741719818296 1.250336932628077 0.9196006746446306 0.2289411404885479 0.0400077618678618 1.0 0.2223047329091382 0.0033507773717699 0.0075753503172145 +Protein phosphatase 2a binding 2 9 2.158241080104857 0.030909093006719 2.478155339805826 9.699029126213592 0.3163362844130395 0.5697991817121072 1.90604773194484 1.6682934217035197 0.7750405605100804 0.2910102683704078 0.0400077618678618 1.0 0.2223047329091382 0.0244664942800011 0.0355737118947821 +Serine hydrolase activity 6 18 2.1367667923562355 0.0326169643477436 6.934466019417476 18.83009708737864 1.2767207242593377 0.1489147276149277 2.386872767465543 1.965791668457755 1.709796217367629 0.2208345231085202 1.0 1.0 1.0 0.0059691990425312 0.0081332818022798 +Inorganic anion transmembrane transporter activity 9 19 2.118318581711466 0.0341480959822027 7.427184466019417 19.274271844660195 1.0921593405593897 0.2441056926448881 3.717191605498929 3.7816647851785734 1.4014196343960104 0.2816216967014333 0.4743210527543476 1.0 1.0 0.1323508586296182 0.0397377338982377 +Peptide antigen binding 1 6 2.103653947577329 0.0354086443838526 2.25 5.218446601941747 1.3488418251083294 0.2076946662826 1.4985834735457568 1.269832767279765 0.9581301458127084 0.2397273125927817 0.1690287978776861 1.0 0.1349531130589082 0.3090006421698555 0.1641299211995837 +Phosphatase activator activity 2 5 2.0932785257135524 0.036324298459051 1.827669902912621 5.038834951456311 0.2237572035576459 0.4866812214382258 1.3004522767274551 1.5083735862416845 1.015613648009018 0.3076019667715845 1.0 1.0 1.0 0.3422564852890665 0.0470360579614364 +Structural constituent of muscle 3 6 2.046621893245484 0.0406952235459185 2.174757281553398 5.813106796116505 0.1661949614229742 0.5170417159203786 1.3842188534663291 1.1327100667826282 0.94905945968665 0.30554266142253 0.2472517806302485 1.0 0.1993869387044997 0.1067922158236129 0.09905667817091 +Protein arginine n methyltransferase activity 3 6 2.010809608386897 0.0443455708495785 2.1092233009708736 5.269417475728155 0.4578179390299605 0.5114911620550099 1.4465265993281495 0.7225471735098173 0.9037274161000616 0.3204634427070337 1.0 1.0 1.0 0.0233125205204954 0.010684483318579 +Gated channel activity 4 13 2.006095200032188 0.0448460918879773 4.317961165048544 13.019417475728156 0.8697524591818097 0.2583579989367679 2.2914716766946497 2.0107989163575497 1.3733766112751231 0.2762671399351702 1.0 1.0 1.0 0.7727677095034151 0.5656452495630921 +Iron ion binding 12 27 2.000583868391625 0.0454372534593414 6.524271844660194 22.196601941747577 0.9076096695164306 0.382669917893863 2.4429198675966717 3.289094676807881 0.9378690899634522 0.3126784916965753 0.0387001795193389 0.2552681350600493 0.4461675288226883 0.016092475953857 0.0026068114295301 +Metalloendopeptidase activity 10 16 1.9653821438751504 0.0493700245891814 5.449029126213592 14.364077669902912 1.4597326207035937 0.2246869419023046 2.4848715129851016 0.6671711573432166 0.9390012824303952 0.2775881383017788 0.3348315497534515 1.0 0.2732850813359189 0.0453869127531283 0.0206839034685982 diff --git a/msigdb_gomf/metrics.json b/msigdb_gomf/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..6d2d94f3c9fee1872a1cfe2d4caff4ce532a2f07 --- /dev/null +++ b/msigdb_gomf/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3381, + "annotations_size": 1388, + "title": "Average number of proteins per term", + "value": 17.544668587896254 +} \ No newline at end of file diff --git a/msigdb_gomf/paths.json b/msigdb_gomf/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..fedf3c644787a4931d4534cd9e4c45fd504bc064 --- /dev/null +++ b/msigdb_gomf/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gomf/fragment/C317/C317_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gomf/result.tsv b/msigdb_gomf/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..04ef63ac691637763f6e2a0a86cab85332e88890 --- /dev/null +++ b/msigdb_gomf/result.tsv @@ -0,0 +1,374 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Ion transmembrane transporter activity 0.5385233802381663 3.961670222835864 7.442729181006413e-05 0.0981516735758388 0.1033050810323704 102 P55011,Q70HW3,O95563,Q96QD8,Q13423,O43681,O43808,P30825,Q8NEW0,P00846,O43772,P0CG08,P05023,O75964,Q9UDW1,Q9HC07,Q9Y6M7,Q93050,P06576,P98194,P21796,Q9H2D1,Q96S66,Q8TB61,Q9Y487,P00403,Q4KMQ2,P13073,Q9HD20,P45880,Q9NWR8,Q6P4Q7,Q9Y5K8,P16615,Q9UBX3,Q9C0H2,Q6P4A7 37 +Tetrapyrrole binding 0.7823494946335904 3.0888443122470632 0.0020093670724843 0.9386896936047192 0.5292679640200179 16 Q16850,P09601,P30519,O43169,Q6UW02,Q8WUJ1 6 +Inorganic molecular entity transmembrane transporter activity 0.5226123008733816 3.014828681582503 0.0025712444644856 0.971942054855869 0.5292679640200179 77 P55011,Q96QD8,Q13423,O43681,P00846,P0CG08,P05023,O75964,Q9UDW1,Q9HC07,Q9Y6M7,Q93050,P06576,P21796,P98194,Q96S66,Q9Y487,P00403,Q4KMQ2,P13073,Q9HD20,P45880,Q6P4Q7,Q9Y5K8,P16615,Q9UBX3,Q9C0H2,Q9NWR8 28 +Cation transmembrane transporter activity 0.5549558130329866 2.9830827269200832 0.0028536085170693 0.9810598390699526 0.5292679640200179 70 P55011,Q70HW3,Q96QD8,Q13423,O43808,P30825,Q8NEW0,P00846,O43772,P05023,O75964,Q9UDW1,Q9HC07,Q9Y6M7,Q93050,P06576,P98194,Q9Y487,P00403,Q4KMQ2,P13073,Q9HD20,Q6P4Q7,P16615,Q9Y5K8 25 +Phosphatase regulator activity 0.652324133261573 2.8032627738990845 0.0050588433206784 0.9991234312609956 0.6383340481001483 23 Q86XL3,P30154,O43768,P0DP25,P78318,Q01105,Q6IN85 7 +Protein phosphatase regulator activity 0.6473240535905083 2.765695843615377 0.005680148641058 0.999631666855244 0.6400025040830793 20 Q86XL3,O43768,P0DP25,P78318,Q01105 5 +Protein transporter activity 0.730281991413721 2.698054080229297 0.0069746109152566 0.9999396094255456 0.6894795210286746 15 O60830,Q9Y5J9,Q9NS69,Q99595,Q9HD20 5 +Transporter activity 0.4828218438205315 2.6759782717763656 0.007451147561549 0.9999689811629724 0.6894795210286746 183 P55011,Q70HW3,O95563,O60830,Q96QD8,Q13423,Q9Y5J9,P03886,Q9NS69,O43681,O43808,Q99595,Q8IXU6,P30825,Q8NEW0,P00846,O43772,O14925,Q07820,P0CG08,P30536,O75964,Q9UDW1,O15173,Q9HC07,Q9Y6M7,Q93050,P56556,Q99567,P06576,O43676,P21796,Q8WTV0,Q03518,Q9H2D1,Q96S66,Q8TB61,Q9Y487,P00403,O96000,P13073,Q9HD20,P38435,P49755,P45880,Q14849,Q9NWR8,Q6P4Q7,Q9Y5K8,P16615,Q9UBX3,Q9C0H2,Q6P4A7 53 +Monooxygenase activity 0.8215792017017667 2.5400798788686147 0.0110827153696235 0.9999998085589038 0.7436572717464233 9 Q9BU89,Q16850,P30519,P09601 4 +Endopeptidase activity 0.507248766400161 2.42264066923077 0.0154081590514074 0.999999999563835 0.7436572717464233 68 P28072,Q9Y4E8,P67812,Q9Y4W6,Q96RU2,P22695,P28074,P20618,P28070,Q9NZ08,P13798,O43464,P52888,P49721,Q6P179,Q4J6C6,Q99436,Q5JRX3,O75844,Q96K76 20 +Macromolecule transmembrane transporter activity 0.6997511307382125 2.313036789868041 0.0207206165005331 0.999999999999761 0.7436572717464233 12 O14925,Q07820,O60830,Q9NS69,Q99595,P49755 6 +Calcium ion binding 0.4001440228986887 2.278555392109227 0.0226935081966945 0.9999999999999856 0.7436572717464233 95 Q13813,Q9Y4G8,Q08209,Q96A33,P80303,Q9Y680,Q96D71,P12814,P41208,Q9BPX6,Q96AY3,O60476,Q8IYU8,P33908,Q14257,P43304,Q9NWM8,O43707,P61201,P67936,P35609,Q8WVQ1,O95302,P0DP25,P16615,O43852 26 +Protein transmembrane transporter activity 0.7183424010376228 2.2777316887176213 0.0227425685025883 0.9999999999999865 0.7436572717464233 11 O14925,Q07820,O60830,Q9NS69,Q99595,P49755 6 +Proton transmembrane transporter activity 0.5695898374428006 2.2677485777196553 0.0233445352046817 0.9999999999999942 0.7436572717464233 36 P00846,O75964,Q9UDW1,Q13423,Q93050 5 +Threonine type peptidase activity 0.7794112291853442 2.235412009024267 0.0253903124290246 0.9999999999999996 0.7436572717464233 8 P28072,P28070,P28074,P20618,P49721 5 +Threonine type endopeptidase activity 0.7794112291853442 2.235412009024267 0.0253903124290246 0.9999999999999996 0.7436572717464233 8 P28072,P28070,P28074,P20618,P49721 5 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen 0.5650919745754783 2.2248169875939894 0.026093526522072 1.0 0.7436572717464233 35 Q16850,P09601,P30519,Q32P28,Q9BU89,Q6UW02,Q9UPP1,Q8IVL6,Q6PK18 9 +Anion channel activity 0.6747006783942051 2.1764319167345594 0.0295229794054847 1.0 0.7436572717464233 12 Q96S66,P0CG08,Q9C0H2,P21796,P45880 5 +Fad binding 0.7447355949261786 2.1751803109447447 0.0296166070236933 1.0 0.7436572717464233 9 O15254,Q15067,O95831,Q15392 4 +Protein phosphatase 2a binding 0.7412462123038595 2.158241080104857 0.030909093006719 1.0 0.7436572717464233 9 P78318,Q86XL3 2 +Serine hydrolase activity 0.5912863086746941 2.1367667923562355 0.0326169643477436 1.0 0.7436572717464233 18 O43464,P67812,Q4J6C6,Q9H3G5,P13798,P42785 6 +Inorganic anion transmembrane transporter activity 0.5722640713576203 2.118318581711466 0.0341480959822027 1.0 0.7436572717464233 19 P55011,Q96S66,P0CG08,Q9Y6M7,O43681,Q9UBX3,Q9C0H2,P21796,P45880 9 +Peptide antigen binding 0.7910316350898099 2.1036539475773295 0.0354086443838526 1.0 0.7436572717464233 6 Q15392 1 +Phosphatase activator activity 0.8382641265621181 2.0932785257135524 0.036324298459051 1.0 0.7436572717464233 5 Q6IN85,P0DP25 2 +Structural constituent of muscle 0.7780737230848379 2.046621893245484 0.0406952235459185 1.0 0.7496634194873628 6 P35609,P67936,P09493 3 +Protein arginine n methyltransferase activity 0.7699773330989367 2.010809608386897 0.0443455708495785 1.0 0.7496634194873628 6 O60678,Q6P2P2,Q86X55 3 +Gated channel activity 0.6345716935459229 2.006095200032188 0.0448460918879773 1.0 0.7496634194873628 13 Q9C0H2,P21796,P0CG08,P45880 4 +Iron ion binding 0.5401382721649467 2.0005838683916255 0.0454372534593414 1.0 0.7496634194873628 27 Q16850,P22830,Q9BV57,P31350,O75845,Q32P28,Q9BU89,Q15800,Q6UW02,Q9UPP1,Q8IVL6,Q6PK18 12 +Metalloendopeptidase activity 0.5936094819684843 1.9653821438751504 0.0493700245891814 1.0 0.7496634194873628 16 Q9BYT8,Q9Y4W6,P22695,Q96TA2,O43847,Q5JRX3,O75844,P42892,P52888,Q10713 10 +Histone acetyltransferase binding 0.7349355491750568 1.9359044420714144 0.0528794056130714 1.0 0.7496634194873628 7 Q8IXJ6,O95905 2 +Voltage gated anion channel activity 0.7346754112734365 1.9347019475852607 0.053026881251871 1.0 0.7496634194873628 7 P21796,P0CG08,P45880 3 +Gtp dependent protein binding 0.6908215077504478 1.9099143391835032 0.0561442435084247 1.0 0.7496634194873628 9 O00429,P53365,Q9BZG1,Q86YV9 4 +Nitric oxide synthase regulator activity 0.7927876924772643 1.902107550364295 0.0571570955845681 1.0 0.7496634194873628 5 P31749 1 +Oxidoreductase activity acting on the ch ch group of donors oxygen as acceptor 0.7918712123886635 1.8982178808143892 0.0576673863056356 1.0 0.7496634194873628 5 Q15067 1 +Protein phosphatase activator activity 0.8313706099095447 1.8420578724132404 0.0654666850940697 1.0 0.7496634194873628 4 P0DP25 1 +Protein arginine omega n monomethyltransferase activity 0.92303562236075 1.8337148320557377 0.066696335766597 1.0 0.7496634194873628 3 Q6P2P2 1 +Phosphatase inhibitor activity 0.6945095354771971 1.8328768105586415 0.0668208930459519 1.0 0.7496634194873628 8 Q01105 1 +Protein methyltransferase activity 0.5156931909110403 1.813340746321762 0.0697792824368155 1.0 0.7496634194873628 27 Q8WTS6,Q03164,O60678,O60725,Q9BV86,Q6P2P2 6 +Oxidoreductase activity acting on a heme group of donors 0.7218349050528974 1.795129422710019 0.0726330819492337 1.0 0.7496634194873628 6 P00403,P16435 2 +Wide pore channel activity 0.8192732781313572 1.7929083967093338 0.0729875725068085 1.0 0.7496634194873628 4 P21796 1 +Porin activity 0.8192732781313572 1.7929083967093338 0.0729875725068085 1.0 0.7496634194873628 4 P21796 1 +Organic cation transmembrane transporter activity 0.8185587147744331 1.789999121472192 0.0734540526298856 1.0 0.7496634194873628 4 O43772,Q70HW3 2 +Ubiquitin conjugating enzyme binding 0.6785429195669858 1.755305455622391 0.079207073810966 1.0 0.7579899953393578 8 Q9BTE7,O75150,Q9UBS8,Q92564 4 +Acyl coa oxidase activity 0.9027026202498618 1.7550662140050326 0.0792479825614123 1.0 0.7579899953393578 3 Q15067 1 +Atpase coupled cation transmembrane transporter activity 0.5818076988670702 1.7523876007196042 0.0797071820557553 1.0 0.7579899953393578 14 Q9UI12,Q9HD20,P05023,P16615,P61421,P06576,Q9Y5K8,P98194,P21281 9 +Protein arginine omega n asymmetric methyltransferase activity 0.9006355400660155 1.7470485449946689 0.0806289177478143 1.0 0.7579899953393578 3 O60678 1 +Sulfur compound transmembrane transporter activity 0.7110225024808345 1.7460726883613524 0.0807983219212316 1.0 0.7579899953393578 6 Q70HW3 1 +Lys48 specific deubiquitinase activity 0.7072253821898928 1.7287940946511118 0.0838459534494133 1.0 0.7712271471597206 6 Q9Y4E8 1 +Cytokine receptor binding 0.5040459672590971 1.7276199544968924 0.084056382885542 1.0 0.7712271471597206 24 P62942,Q9Y4E8,Q9H2J4,Q9NZ08,P48681,Q8WXW3,P14174 7 +Peptidyl proline dioxygenase activity 0.7508886255924113 1.7228779773341514 0.0849105936436065 1.0 0.7712271471597206 5 P07237,Q8IVL6,P13674,Q32P28 4 +Procollagen proline dioxygenase activity 0.7508886255924113 1.7228779773341514 0.0849105936436065 1.0 0.7712271471597206 5 P07237,Q8IVL6,P13674,Q32P28 4 +Proton transporting atp synthase activity rotational mechanism 0.6100231902516922 1.696610090026351 0.0897704009346349 1.0 0.7886159271979324 11 P00846 1 +Proton channel activity 0.6100231902516922 1.696610090026351 0.0897704009346349 1.0 0.7886159271979324 11 P00846 1 +Udp glucosyltransferase activity 0.6955128328053171 1.6753357560594242 0.0938683737326395 1.0 0.7915077663472508 6 P13807,Q16739 2 +Mhc protein binding 0.6254679076692131 1.6743493331387784 0.0940619642386009 1.0 0.7915077663472508 10 Q9NUQ9,Q03518 2 +Peptidase activity 0.3710396299257588 1.6713861606164808 0.0946454276985 1.0 0.7915077663472508 117 P28072,Q9Y4E8,P67812,Q9H3G5,Q9Y4W6,Q96RU2,P22695,P28074,Q969V3,P20618,Q9H8M7,P28070,Q9NZ08,P55786,P13798,O43464,P52888,P49721,Q9BT78,Q6P179,Q4J6C6,Q99436,Q5JRX3,O75844,Q96K76,P42785 26 +Structural constituent of synapse 0.6518723352619887 1.6245310138680396 0.1042625268554284 1.0 0.7915077663472508 8 Q8IUD2,P07196,P12814,O15020 4 +Phosphatidylcholine binding 0.6659833479428767 1.6123048620496323 0.1068956158267355 1.0 0.7915077663472508 7 O43633,P21796 2 +Transferase activity transferring sulphur containing groups 0.6476003559499757 1.603453199407418 0.1088346337980055 1.0 0.7915077663472508 8 Q8NCH0 1 +Voltage gated channel activity 0.5925305803175661 1.5995993131087474 0.1096875009450133 1.0 0.7915077663472508 11 P21796,P0CG08,P45880 3 +Phosphatidic acid binding 0.8567265435192062 1.5759032188569473 0.1150481090647144 1.0 0.7915077663472508 3 Q9Y4G8 1 +Protein carrier chaperone 0.5876908697011175 1.5726231432847162 0.1158061055659513 1.0 0.7915077663472508 11 P40855,P10909,Q9Y5J7,Q8N8Q8,Q9NPA0,P11142 6 +Mhc class ib protein binding 0.855440384879801 1.570869282746766 0.1162130149087468 1.0 0.7915077663472508 3 Q9NUQ9 1 +Phosphatidylinositol 4 phosphate binding 0.6225486214186253 1.5637667323908426 0.117872359608012 1.0 0.7915077663472508 9 P53365,Q9H4A5,Q9H4A6 3 +Peptide binding 0.3949106834373914 1.561609019708422 0.118380123329596 1.0 0.7915077663472508 77 P40855,Q9Y287,Q08209,Q15388,P30533,P42892,P50542,P24390,P10909,O00410,Q9NZ08,P55786,Q15392,O00264,Q8WTV0,O15212,Q03518,Q9UHV9,O43731,Q92973,Q9BYT8,Q6P179,Q8TEX9 23 +Passive transmembrane transporter activity 0.4798869707666602 1.545187270535473 0.1223009724836281 1.0 0.7915077663472508 36 P00846,Q96S66,P0CG08,O75964,Q4KMQ2,P06576,Q9C0H2,Q9NWR8,P21796,P45880 10 +Endopeptidase activator activity 0.706789541738036 1.5314442732435016 0.1256596291750447 1.0 0.7915077663472508 5 P61289,Q06323 2 +Guanylate kinase activity 0.7067535545023621 1.5312870524935749 0.1256984640670229 1.0 0.7915077663472508 5 O14936,Q14168,Q9UDY2,Q00013 4 +Fk506 binding 0.6485699047726529 1.529181606894548 0.126219429010753 1.0 0.7915077663472508 7 Q96AY3,Q9Y680 2 +Macrolide binding 0.6485699047726529 1.529181606894548 0.126219429010753 1.0 0.7915077663472508 7 Q96AY3,Q9Y680 2 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced flavin or flavoprotein as one donor and incorporation of one atom of oxygen 0.979875702870672 1.526265966042433 0.1269436409309055 1.0 0.7915077663472508 2 P30519 1 +Er retention sequence binding 0.9778040840485354 1.5181456840203085 0.128977676662283 1.0 0.7915077663472508 2 P24390 1 +Gtpase binding 0.3459972100093944 1.5074976488607212 0.1316831460437326 1.0 0.7915077663472508 96 Q9Y2T2,Q96P70,Q13439,Q9BZG1,Q8TBA6,P50542,Q9NSV4,Q9NUQ9,O00429,O00410,Q8TD16,Q7L576,Q9Y3P9,Q01082,P67809,P53365,Q9UJY4,O75116,P49815,Q92973,Q96A65,Q8IUD2,Q86YV9,Q14C86,O14641,Q8TEX9 26 +Amyloid beta binding 0.5411458877539107 1.5029234925555788 0.1328587741781 1.0 0.7915077663472508 14 Q9UHV9,P10909,Q9Y287,P30533,Q8WTV0,O15212 6 +Calcium channel regulator activity 0.7476270173603796 1.4982323587894062 0.1340728911422108 1.0 0.7915077663472508 4 Q9NWR8 1 +Steroid binding 0.4733860278016528 1.4944579093803498 0.1350559753709308 1.0 0.7915077663472508 23 P05023,P30536,O15173,Q14849,O00264,P21796,P38435,P45880 8 +Structural constituent of cytoskeleton 0.4734971690056778 1.485560628033899 0.1373953756950101 1.0 0.7915077663472508 34 Q96RT1,P07197,Q13813,P07196,P35612,P08670,Q9UEY8,O15020,P09493,Q01082,Q16204,O15144 12 +Manganese ion transmembrane transporter activity 0.8315571343990423 1.477232656253479 0.1396132828680745 1.0 0.7915077663472508 3 Q9HD20,Q9HC07 2 +Transition metal ion transmembrane transporter activity 0.8315571343990423 1.477232656253479 0.1396132828680745 1.0 0.7915077663472508 3 Q9HD20,Q9HC07 2 +Snap receptor activity 0.5177887349419245 1.4743256670608402 0.1403939276158652 1.0 0.7915077663472508 16 O95249,O43752,O95721,Q13277,Q13190,Q9P2W9 6 +Sulfotransferase activity 0.9659662622077538 1.4717449198877162 0.1410897724681217 1.0 0.7915077663472508 2 Q8NCH0 1 +Transmembrane transporter binding 0.4706390497181866 1.4648385376301143 0.1429649748547905 1.0 0.7915077663472508 35 P35609,P62942,P30536,P0DP25,P16615,Q99996,O43707,P42858,P12814,P21796 10 +Structural constituent of postsynapse 0.6905915776564188 1.460539909336814 0.1441417474619708 1.0 0.7915077663472508 5 P12814,P07196,Q16352 3 +Phospholipid binding 0.3416374535515286 1.4539644871056467 0.145956152262882 1.0 0.7915077663472508 95 O43633,Q5MNZ6,Q9H4A5,Q9Y4G8,O60313,Q9Y5X3,P31749,Q9UNH7,Q9H4A6,Q9H6U6,P21796,Q01082,Q8WTV0,O15294,P53365,Q15075,Q9UJY4,P45880,P35609,Q9BPX3,O14964,Q9Y2I1,P09429,O15020 24 +Hsp70 protein binding 0.5141455838082539 1.450252191253377 0.1469882057382263 1.0 0.7915077663472508 16 O60884,O75937,P46379,P06493,P23396,Q07812 6 +Organophosphate ester transmembrane transporter activity 0.583583290015691 1.450121899743693 0.1470245291227974 1.0 0.7915077663472508 10 Q9H2D1,O43808,Q8TB61 3 +Nucleotide transmembrane transporter activity 0.583583290015691 1.450121899743693 0.1470245291227974 1.0 0.7915077663472508 10 Q9H2D1,O43808,Q8TB61 3 +Molecular transducer activity 0.4673653470452991 1.437703173416009 0.1505182923129011 1.0 0.79436752058404 35 Q99720,P30536,Q9UBG0,O15173,O15031,P41214,Q15629,Q8WTV0,P10586 9 +Anion transmembrane transporter activity 0.4584792868310137 1.4249434618734291 0.1541735449536183 1.0 0.79436752058404 45 P55011,Q9H2D1,Q96S66,O95563,P0CG08,Q8TB61,Q96QD8,Q9Y6M7,O43681,O43808,P30825,Q9UBX3,Q9C0H2,P21796,P45880 15 +Pdz domain binding 0.5094619925932461 1.419251993325222 0.1558255626076166 1.0 0.79436752058404 16 Q96A65,Q9Y4G8,Q9UQB8,Q8IUD2,Q15067 5 +Nadplus binding 0.6082330128340419 1.407740657925045 0.1592078778669776 1.0 0.79436752058404 8 Q8IXJ6,Q8NBZ7 2 +Nucleotidase activity 0.6229130468475301 1.4058844684660816 0.159758434034656 1.0 0.79436752058404 7 Q969T7 1 +Misfolded protein binding 0.5253041373106454 1.40448421903229 0.1601747076918336 1.0 0.79436752058404 14 P46379 1 +Phosphatidylinositol 3 kinase binding 0.7201905700791912 1.3841575234075 0.1663102264524125 1.0 0.7967941818192075 4 P0DP25,P50570 2 +Signaling receptor regulator activity 0.4687651069517178 1.3732181374700192 0.1696845427905249 1.0 0.7967941818192075 19 Q9UMX5,P30533,P09429,P51858,Q15276,P43490,P14174 7 +Dioxygenase activity 0.4569226451292023 1.3662735441795708 0.1718531215140026 1.0 0.7967941818192075 23 Q32P28,Q9UPP1,O00625,P16435,Q8IVL6,Q6PK18 6 +P type transmembrane transporter activity 0.6689393885470194 1.365389861125672 0.1721305488419351 1.0 0.7967941818192075 5 P16615,P05023 2 +Rna polymerase ii general transcription initiation factor activity 0.625083659588173 1.3495146413443917 0.1771717207577923 1.0 0.7984408647977534 6 P35269,P29083,Q15545,O00268 4 +Rna strand annealing activity 0.6632849407311616 1.340487309016207 0.1800869675624605 1.0 0.7984408647977534 5 Q06787,P23588,Q15056 3 +Peptide alpha n acetyltransferase activity 0.7048131052833224 1.3200590812771231 0.1868152930488618 1.0 0.7984408647977534 4 Q86UY6 1 +Rage receptor binding 0.7912966252220213 1.3189947800528945 0.1871708575808228 1.0 0.7984408647977534 3 P26583,P09429 2 +Omega peptidase activity 0.4512941414145317 1.317507504178148 0.1876685673588691 1.0 0.7984408647977534 24 Q96K76,Q9Y4E8,Q9H8M7,P13798 4 +Ubiquitin like protein conjugating enzyme binding 0.5246326701413213 1.31625569384611 0.1880882363023213 1.0 0.7984408647977534 12 Q9BTE7,O75150,Q9UBS8,Q92564 4 +Growth factor receptor binding 0.4832727626025398 1.3116960436588423 0.1896227122063811 1.0 0.7984408647977534 17 Q92990,Q9H2J4,O60749,Q9NZ08,Q8WXW3 5 +Polyubiquitin modification dependent protein binding 0.4931797825343176 1.3110790990553902 0.1898310413424053 1.0 0.7984408647977534 16 Q9UMX0,P46379 2 +Nucleobase containing compound transmembrane transporter activity 0.5223759352606756 1.3028756255330634 0.1926172266450501 1.0 0.8004572173153579 12 Q9H2D1,O43808,Q8TB61 3 +Cytoskeleton nuclear membrane anchor activity 0.7865600947306177 1.3003755967812494 0.1934722696140838 1.0 0.801428043605528 3 Q8WXH0,O94901 2 +Kinesin binding 0.5083970524373095 1.2988202138151608 0.1940056359160356 1.0 0.801428043605528 14 O60333,Q96EK5,O60271,Q9H0B6 4 +Mannosyl oligosaccharide mannosidase activity 0.7847801281376194 1.2933796890823102 0.195879771363189 1.0 0.804382019680788 3 P33908 1 +Dolichyl diphosphooligosaccharide protein glycotransferase activity 0.6927130593627167 1.2695842944036848 0.2042327467659834 1.0 0.8241657946814998 4 P04843 1 +Proteasome binding 0.5332078433924051 1.265582394666999 0.2056626324032364 1.0 0.8250281322996885 11 O95456,P46379 2 +Mannosyl oligosaccharide 1 2 alpha mannosidase activity 0.9121041728322 1.2611289750727577 0.2072623827693578 1.0 0.826667204838703 2 P33908 1 +Oxidoreductase activity acting on a sulfur group of donors oxygen as acceptor 0.6872317891390521 1.2467173379135743 0.212501159250996 1.0 0.8285157557314113 4 Q9UHG3 1 +Acetylgalactosaminyltransferase activity 0.7690941385435249 1.2317700193526162 0.2180350055675575 1.0 0.8360016235573751 3 Q10471,Q10472 2 +Polypeptide n acetylgalactosaminyltransferase activity 0.7690941385435249 1.2317700193526162 0.2180350055675575 1.0 0.8360016235573751 3 Q10471,Q10472 2 +D1 dopamine receptor binding 0.7681296934722381 1.2279852518875725 0.2194525043576711 1.0 0.8365829324448301 3 Q9Y5X3 1 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen nad p h as one donor and incorporation of one atom of oxygen 0.7668813050312488 1.22308691128813 0.221296871672906 1.0 0.8365829324448301 3 Q16850 1 +Microtubule minus end binding 0.6353706925930779 1.21736718779941 0.2234645414404559 1.0 0.8365829324448301 5 Q9H6D7 1 +Amide transmembrane transporter activity 0.5964076580421963 1.2153992091951495 0.2242138695025048 1.0 0.8365829324448301 6 Q9H2D1 1 +Beta tubulin binding 0.4687638324517779 1.2115593292512623 0.2256811109488803 1.0 0.8375678561284974 17 O75381,P50402,O14737,P42858,P42704 5 +Titin binding 0.8961231133471446 1.1990160715053184 0.2305216964494381 1.0 0.8375678561284974 2 P0DP25 1 +Adrenergic receptor binding 0.6711502063569689 1.179656502884443 0.2381368604146727 1.0 0.8482374084616846 4 Q9Y4G8 1 +Dynactin binding 0.5875901670418787 1.1741016831084283 0.2403542994041672 1.0 0.8482374084616846 6 Q8TD16,Q9Y5X3,P42858,Q9UNH7 4 +Pentosyltransferase activity 0.4807460517302772 1.1720796418505113 0.2411650825798688 1.0 0.8482374084616846 15 Q8IXJ6,Q13126,Q06203 3 +Protein kinase a catalytic subunit binding 0.6235189573459636 1.16507187544743 0.2439899000882606 1.0 0.8482374084616846 5 P15311,P41240,P10644,P49841 4 +Calcium channel inhibitor activity 0.8857650192364612 1.158911470469324 0.2464922728731977 1.0 0.8482374084616846 2 Q9NWR8 1 +Procollagen proline 4 dioxygenase activity 0.7504440497335663 1.1586823221996272 0.246585699163333 1.0 0.8482374084616846 3 P07237,P13674 2 +Peptidyl proline 4 dioxygenase activity 0.7504440497335663 1.1586823221996272 0.246585699163333 1.0 0.8482374084616846 3 P07237,P13674 2 +Antigen binding 0.5585144694373321 1.1579282716277697 0.2468933090911531 1.0 0.8482374084616846 8 Q15392 1 +Transforming growth factor beta receptor binding 0.6204242468782105 1.1514219164542754 0.2495587016997 1.0 0.855277723356009 5 Q9Y4E8,P62942 2 +High density lipoprotein particle binding 0.7457924483654053 1.1404940541007165 0.2540805284514555 1.0 0.8638665204779998 3 Q9BQE5 1 +Armadillo repeat domain binding 0.6614878538339111 1.1394115425305948 0.2545315439117459 1.0 0.8638665204779998 4 Q9P1Z2 1 +P type calcium transporter activity 0.7438772744587039 1.1330113200048468 0.2572094995854694 1.0 0.8665213238461933 3 P16615 1 +Metal ion transmembrane transporter activity 0.4259494284178133 1.1175595938111118 0.2637551341006952 1.0 0.8699788747244831 24 P55011,P05023,Q96QD8,Q6P4Q7,Q9HC07,Q9Y6M7,P16615,Q9HD20 8 +Ubiquitin like protein binding 0.4275525556741145 1.111105058926621 0.2665231305827187 1.0 0.874548712172136 38 Q9BTE7,Q13501,Q92564,Q8IXJ6,Q8IZL8 5 +Glucosyltransferase activity 0.5187655026049054 1.0977351668381048 0.2723201489515019 1.0 0.8786062418797234 10 P13807,Q16739 2 +Oxidoreductase activity acting on single donors with incorporation of molecular oxygen 0.8688961231133481 1.0939229210801569 0.2739887850336426 1.0 0.8786062418797234 2 O00625 1 +Translation activator activity 0.6504807420417547 1.093640464557122 0.2741126948594981 1.0 0.8786062418797234 4 Q9H074,Q7Z478 2 +Nucleocytoplasmic carrier activity 0.4194327758406933 1.0929429227211866 0.2744188609638502 1.0 0.8786062418797234 20 O00410,Q96P70,O60684,Q9C0E2,O15504,P55060,Q8TEX9,Q92973 8 +Cation channel activity 0.4190492954264831 1.0899657826398772 0.2757282171447579 1.0 0.8797948629814345 20 P00846 1 +Growth factor activity 0.5689327605777061 1.0867510565291645 0.2771468432405379 1.0 0.8799974725768558 6 Q9UMX5,P51858 2 +Organic anion transmembrane transporter activity 0.4249468238510587 1.0866563311221733 0.2771887198926079 1.0 0.8799974725768558 30 Q9H2D1,O95563,Q8TB61,Q96QD8,Q9Y6M7,P30825,Q9UBX3 7 +Histone methyltransferase activity 0.4398809046767644 1.079186574378619 0.2805045634122041 1.0 0.8853742315488303 18 Q03164,Q8WTS6,Q9BV86 3 +Metalloexopeptidase activity 0.4171636903540336 1.0753272837190024 0.2822282250738008 1.0 0.8853742315488303 20 P55786,O75844,Q9NZ08,Q6P179 4 +Molecular carrier activity 0.4234746562495665 1.0705345763854517 0.2843787540746998 1.0 0.8870060913610861 34 O75880,P40855,P10909,Q9Y5J7,O00410,Q96P70,Q8N8Q8,Q15006,Q9NPA0,O60684,Q9C0E2,O15504,P11142,Q8TEX9,Q92973 15 +Phosphatidylinositol 3 5 bisphosphate binding 0.6012351020843525 1.0668964069978006 0.2860186175052712 1.0 0.8887875927410921 5 Q9Y5X3,Q5MNZ6,Q92538 3 +Tropomyosin binding 0.7251585695386674 1.0600897776340392 0.2891037579003921 1.0 0.8957053927806792 3 Q9NYL9 1 +General transcription initiation factor activity 0.5448688829859283 1.027764887551508 0.3040604366829749 1.0 0.9194681614726996 7 P35269,P29083,Q15545,O00268 4 +Intermediate filament binding 0.5553310032910421 1.0231916910026893 0.3062172207523306 1.0 0.921874567202214 6 P08670 1 +L ascorbic acid binding 0.5171049385486732 1.0143059959472478 0.3104367638662093 1.0 0.921874567202214 9 Q8IVL6,Q6PK18 2 +Protein self association 0.4886116923410489 1.011753554550875 0.3116559021728879 1.0 0.921874567202214 11 Q9Y282 1 +Dopamine receptor binding 0.5520581993954343 1.00792496253637 0.3134904868295713 1.0 0.921874567202214 6 Q9Y5X3,Q96QK1 2 +Transcription coactivator binding 0.551644371413911 1.0059954735170935 0.31441774747706 1.0 0.9226333151610464 6 Q71SY5 1 +Serine type exopeptidase activity 0.539034194668892 0.9995443975485682 0.3175310430001765 1.0 0.9247996953062628 7 P42785 1 +Calcium dependent protein serine threonine phosphatase activity 0.7090467755837845 0.9977160234907312 0.3184170810153484 1.0 0.9247996953062628 3 Q08209 1 +Serine type carboxypeptidase activity 0.5850981554930892 0.9960732598222208 0.3192145512013411 1.0 0.9247996953062628 5 P42785 1 +Palmitoyltransferase activity 0.5835610478427483 0.989344757317068 0.3224944928776274 1.0 0.9248395787482372 5 P23786,O15269 2 +Peroxisome targeting sequence binding 0.7021906453522745 0.971311941965 0.3313929638052757 1.0 0.9320993270931044 3 P40855,P50542 2 +Oligosaccharyl transferase activity 0.5765049050157025 0.9585057251562726 0.3378078059389335 1.0 0.9356568642996428 5 P04843 1 +Sodium ion transmembrane transporter activity 0.5060683765556372 0.9566991387709974 0.3387191329541834 1.0 0.9356568642996428 9 P55011,Q96QD8,Q6P4Q7,Q9Y6M7 4 +Atpase binding 0.4086834707856398 0.9542274182261394 0.3399685387462119 1.0 0.9360264396852456 30 Q8IZL8,Q9Y487,P40855,Q93050 4 +Active ion transmembrane transporter activity 0.4069177204906022 0.9473791619331816 0.3434456055840758 1.0 0.9365471523589336 42 P55011,Q96QD8,P61421,P47985,O95202,P05026,P05023,Q9UDW1,Q9Y6M7,P06576,P98194,P00403,P13073,Q9HD20,P21281,Q9UI12,P16615,Q9Y5K8,P20674 19 +G protein coupled receptor binding 0.4071167546585656 0.941491240170114 0.3464531762363301 1.0 0.9407111763347532 30 Q9Y5X3,Q96D09,Q9Y4G8,P48681,P0DP25,O14641,P50570,Q96QK1 8 +Intracellular calcium activated chloride channel activity 0.8242083456643996 0.924465176860439 0.3552441740271534 1.0 0.9500557101150076 2 Q9C0H2 1 +Ion gated channel activity 0.8242083456643996 0.924465176860439 0.3552441740271534 1.0 0.9500557101150076 2 Q9C0H2 1 +Sterol binding 0.4173902544459901 0.918077597528638 0.3585782423640189 1.0 0.951235698379262 18 P21796,P45880,P30536 3 +L amino acid transmembrane transporter activity 0.4982470799366052 0.9159891934738816 0.3596725629030088 1.0 0.951235698379262 9 Q96QD8,Q9Y619,P30825 3 +Metalloaminopeptidase activity 0.4567188776338127 0.9122189290529508 0.3616534812915069 1.0 0.951235698379262 12 P55786,Q9NZ08 2 +Tubulin binding 0.3099679391766507 0.9040785193395996 0.3659537676818203 1.0 0.9553560337058156 104 P07197,Q14166,Q2M1P5,O60313,Q96ED9,O14737,P50570,P42858,P42704,Q9UQE7,Q7Z4H7,P41208,Q9BSJ2,O75381,Q96TC7,P33176,O00429,O60333,Q08379,Q8NBT2,Q96DB5,P15311,Q9Y3P9,Q9H6D7,Q9H6U6,Q14203,P12270,P25054,Q9UH99,Q8IWS0,P16949,Q9H6H4,Q15555,O43292,P50402,Q15058,Q9UPN3 37 +2 acylglycerol 3 phosphate o acyltransferase activity 0.6820603907637693 0.8943753888299593 0.3711210759343242 1.0 0.9553560337058156 3 Q96N66,Q8NF37 2 +Demethylase activity 0.453533841061989 0.8933418031163836 0.3716741579796274 1.0 0.9553560337058156 12 Q16850 1 +Microfilament motor activity 0.4928322424395208 0.8878772013500337 0.3746068095787964 1.0 0.9553560337058156 9 P60660,P35579,P35580,Q7Z406 4 +Alcohol binding 0.4218484648508392 0.8872893882822245 0.3749231173114249 1.0 0.9553560337058156 17 P21796,P45880,P30536 3 +Glutamate receptor binding 0.5151228012927411 0.8844400319902384 0.3764587209268051 1.0 0.9553560337058156 7 P0DP25 1 +Aminopeptidase activity 0.4421854350750037 0.8829152571706789 0.3772820595412156 1.0 0.9553560337058156 14 P55786,Q9NZ08 2 +Cholesterol binding 0.4342472438199999 0.8711583977098704 0.3836676717923413 1.0 0.957789079942032 15 P21796,P45880,P30536 3 +Lipopolysaccharide binding 0.5116836663506116 0.8679826749394348 0.3854038171372058 1.0 0.959764862216704 7 P28070,Q8WTV0 2 +Nitric oxide synthase binding 0.8040840485350718 0.8499094698178375 0.3953754202266673 1.0 0.9647298740058692 2 P0DP25 1 +Lipid binding 0.3364445770259404 0.8481053341082783 0.3963793112481488 1.0 0.9647298740058692 155 O43633,Q5MNZ6,Q9H4A5,Q9Y4G8,O60313,Q9BQE5,Q9Y5X3,P28070,P05023,P30536,P31749,O15173,O94788,O00429,Q13277,Q9UNH7,Q9H4A6,O00264,Q9H6U6,P21796,A6NIH7,Q8WTV0,Q01082,O15294,P53365,O75208,Q15075,Q9UJY4,O15254,P38435,P45880,P35609,Q9BPX3,O95772,Q14849,Q15067,O14964,Q9Y2I1,P09429,O15020 40 +Active transmembrane transporter activity 0.3329329358406817 0.8370568039692036 0.402560639297632 1.0 0.9647298740058692 78 P55011,Q96QD8,Q15388,P03886,P05023,Q9UDW1,Q9Y6M7,P56556,P06576,O43676,P98194,Q03518,P00403,O96000,P13073,Q9HD20,O43674,P16615,Q9UBX3,Q9Y5K8 20 +Atpase coupled transmembrane transporter activity 0.3872124468636131 0.8058048138793702 0.4203554019479947 1.0 0.9724221631730278 25 Q9UI12,P05023,Q15388,Q9Y5K8,P16615,P61421,P06576,Q9HD20,P98194,P21281,Q03518 11 +Aldehyde dehydrogenase nad p plus activity 0.4871466585873342 0.8007933714650636 0.4232512770352359 1.0 0.9746334949018056 8 P30837,P51648 2 +Type i transforming growth factor beta receptor binding 0.6555425803444256 0.7947221021183436 0.4267751726518614 1.0 0.9746334949018056 3 P62942 1 +Dynein heavy chain binding 0.6551213735938477 0.7931579147643908 0.4276858238506278 1.0 0.9746334949018056 3 Q9Y6G9,Q13409 2 +Ceramide binding 0.5376077340920631 0.7905125764266319 0.4292284804328508 1.0 0.9746334949018056 5 P21796,P45880 2 +Signal sequence binding 0.3854019311703272 0.7746588809387724 0.4385412544153406 1.0 0.9762250428182004 28 P40855,O00410,O43731,Q15388,P50542,Q8TEX9,Q92973,P24390 8 +Peptidase activator activity 0.4317712422598734 0.7651447337694872 0.4441853647423874 1.0 0.9762250428182004 12 Q9UL46,Q06323,Q9BXK5,P61289 4 +Channel regulator activity 0.3768532457487972 0.7641300059804265 0.4447897725469478 1.0 0.9762250428182004 20 Q9NWR8,P62942,O43768,P31749 4 +H4 histone acetyltransferase activity 0.6444641799881478 0.753804571004845 0.4509665788460468 1.0 0.9762250428182004 3 Q9GZZ1,Q86UY6 2 +Supercoiled dna binding 0.5282519508632362 0.7508060769191193 0.4527693716599259 1.0 0.9762250428182004 5 P26583,P09429 2 +Glyceraldehyde 3 phosphate dehydrogenase nadplus non phosphorylating activity 0.5279512549554559 0.7495356288096942 0.4535344325480603 1.0 0.9762250428182004 5 P51648 1 +Dynein complex binding 0.4863385412498081 0.7478205896257502 0.4545683811491301 1.0 0.9762250428182004 7 P12270,Q8TD16,P25054,Q9UQE7 4 +Oxidoreductase activity acting on paired donors with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 0.6426879810538839 0.7472893346817671 0.4548889289654003 1.0 0.9762250428182004 3 O75845,O95864 2 +Exopeptidase activity 0.3824521785419263 0.7422357191362371 0.4579445305749918 1.0 0.9762250428182004 30 Q6P179,Q9H3G5,Q9NZ08,P55786,O75844,P42785 6 +Phosphoric diester hydrolase activity 0.4407917655062566 0.742038522083879 0.4580639961659716 1.0 0.9762250428182004 11 P09601 1 +Vitamin transmembrane transporter activity 0.4848769539978625 0.7409641242472886 0.4587151931291047 1.0 0.9762250428182004 7 Q9H2D1 1 +Nuclear export signal receptor activity 0.4742370187733611 0.7374905438954477 0.4608240915954855 1.0 0.9762250428182004 8 Q9C0E2,O15504 2 +Ubiquitin like protein specific protease activity 0.3813404132989433 0.7295576598143427 0.4656606108226568 1.0 0.9762250428182004 31 Q9Y4E8,Q96RU2,P51665,Q96K76,Q9H8M7,Q9Y4P1,Q9BT78 7 +Channel inhibitor activity 0.4725124190379512 0.7290872277656077 0.4659483068766055 1.0 0.9762250428182004 8 Q9NWR8,O43768 2 +Phosphotransferase activity for other substituted phosphate groups 0.5205409024417791 0.7183487013973322 0.4725423084484046 1.0 0.9762250428182004 5 Q9NRN7,Q9H9S5 2 +1 phosphatidylinositol binding 0.4886591509801433 0.716754947651319 0.4735253148622742 1.0 0.9762250428182004 6 Q8WTV0 1 +Phosphatidylinositol phosphate binding 0.3797638464304054 0.7067845350616759 0.4797003865241642 1.0 0.9776736332214696 35 P35609,Q9Y5X3,Q5MNZ6,P53365,Q9H4A5,P31749,Q9H4A6,O15294 8 +Ribosomal protein s6 kinase activity 0.7611719443622403 0.6961257886688488 0.4863500575484782 1.0 0.9776736332214696 2 Q15418 1 +Phosphatidylinositol binding 0.3578956342771877 0.6956148231844163 0.4866700805724733 1.0 0.9776736332214696 62 Q13045,Q9Y5X3,Q5MNZ6,P53365,Q9H4A5,P35609,Q9BPX3,P31749,O60749,O14964,Q9Y2I1,Q9H4A6,Q9UNH7,Q15075,Q9UJY4,Q9H6U6,Q8WTV0,O15294 18 +Oxidoreduction driven active transmembrane transporter activity 0.3761034491778172 0.6840562405695726 0.4939396527614468 1.0 0.9776736332214696 32 Q9UDW1,P00403,P03886,O96000,P13073,O43676 6 +Map kinase kinase activity 0.4808888888888917 0.6820429871857475 0.495211769431213 1.0 0.9776736332214696 6 Q96KB5,P45985,P28482,P27361,Q02750 5 +Class i dna apurinic or apyrimidinic site endonuclease activity 0.757028706717967 0.6817325868617576 0.495408058026312 1.0 0.9776736332214696 2 P78549 1 +Camp dependent protein kinase regulator activity 0.6231497927767979 0.6765396544919193 0.4986980780409225 1.0 0.9776736332214696 3 P10644,P54619 2 +Membrane insertase activity 0.459791934978736 0.6675605786825186 0.5044141284909833 1.0 0.978118735789045 8 Q9Y5J7,Q8N8Q8,Q9NPA0 3 +L ornithine transmembrane transporter activity 0.7522935779816546 0.6653957718343937 0.5057973885870974 1.0 0.978118735789045 2 P30825 1 +Rrna cytosine methyltransferase activity 0.6170013302123297 0.6546560225659188 0.5126892456976451 1.0 0.978118735789045 3 Q96P11 1 +Metallopeptidase activity 0.3726118502847119 0.6520866607581881 0.5143452687541714 1.0 0.978118735789045 43 Q9BYT8,Q6P179,Q9Y4W6,P22695,Q9NZ08,P51665,Q969V3,P55786,Q5JRX3,O75844,P52888,Q10713,O15372 13 +Syntaxin binding 0.363212783789072 0.6515896690978924 0.5146659140102154 1.0 0.978118735789045 21 O43752,O95721,Q08379,Q6ZWJ1,P49755,O75150 6 +Atpase coupled intramembrane lipid transporter activity 0.5365709209357304 0.6347671038451262 0.5255803211261436 1.0 0.9890349027298349 4 Q96AA3,P08183,Q9NV96 3 +Protein lipid complex binding 0.4964988925516713 0.6190297523942594 0.5358967589059489 1.0 0.9913629438516838 5 Q9BQE5 1 +Mdm2 mdm4 family protein binding 0.4642657274086486 0.6088925430174478 0.5425956672877346 1.0 0.9923371561981889 6 Q96JB5 1 +Cis trans isomerase activity 0.3630147808289409 0.6047083977259072 0.5453727673293276 1.0 0.9923371561981889 27 P62942,Q9Y237,Q96AY3,O95302,Q9Y680,Q9NWM8,Q5T1M5 7 +Nuclear import signal receptor activity 0.4039452548020322 0.6044958162180423 0.545514049948213 1.0 0.9923371561981889 12 O00410,O60684,Q96P70,Q8TEX9,Q92973 5 +Organic acid transmembrane transporter activity 0.3589830083131778 0.5947402178482852 0.5520171340166777 1.0 0.9963586242069554 24 Q9UBX3,Q96QD8,Q9H2D1,P30825 4 +Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor 0.3944473309307237 0.589721104202772 0.5553776439939415 1.0 0.9983872515625294 14 Q8N4Q0 1 +C3hc4 type ring finger domain binding 0.5973949082297325 0.586270457105296 0.5576937806928299 1.0 0.9983872515625294 3 P0DMV9,P11142 2 +Atp dependent peptidase activity 0.4589001880846437 0.5856509634520036 0.5581100931661094 1.0 0.9983872515625294 6 Q9Y4W6 1 +Dynein light intermediate chain binding 0.4554243569758307 0.570702186205471 0.5682015365996942 1.0 0.9992992245588496 6 Q96ED9,Q8TD16 2 +Plus end directed microtubule motor activity 0.4392887815567198 0.5704324082356347 0.5683844539497418 1.0 0.9992992245588496 8 O60333,P33176 2 +P type potassium transmembrane transporter activity 0.7235868600177602 0.5691822934638392 0.5692324356353153 1.0 0.9992992245588496 2 P05023 1 +Solute sodium symporter activity 0.4838863245470794 0.5682932156762347 0.5698358849432044 1.0 0.9992992245588496 5 Q96QD8,Q9Y6M7 2 +Pyrophosphate hydrolysis driven proton transmembrane transporter activity 0.4377999168808101 0.563495636269093 0.5730974307123211 1.0 0.9992992245588496 8 Q9UI12,Q9Y5K8,P21281,P06576 4 +Atpase coupled ion transmembrane transporter activity 0.4377999168808101 0.563495636269093 0.5730974307123211 1.0 0.9992992245588496 8 Q9UI12,Q9Y5K8,P21281,P06576 4 +Collagen binding 0.4079733897345769 0.5627491819122195 0.5736056889599932 1.0 0.9992992245588496 11 O75718,Q32P28,Q92791 3 +Fucosyltransferase activity 0.7203314590115457 0.5586061871365009 0.5764305165316084 1.0 0.9992992245588496 2 Q9Y2G5 1 +Intramembrane lipid transporter activity 0.4485925925925955 0.5415824576215579 0.5881061792860938 1.0 1.0 6 Q8NB49,P08183,Q4KMQ2,Q9NV96,Q96AA3 5 +Aryl hydrocarbon receptor binding 0.714412548091155 0.5395671272855413 0.5894955919235974 1.0 1.0 2 O00170 1 +Primary active transmembrane transporter activity 0.3479171722448159 0.5254350922430006 0.5992807639247757 1.0 1.0 57 O75306,O95298,Q15388,P03886,P61421,O95168,P47985,P05023,P05026,Q9UDW1,P56556,P06576,Q9Y6M9,O43676,P98194,Q03518,P00403,O96000,P13073,Q9HD20,P21281,Q9UI12,O43674,P16615,Q9Y5K8,P20674 26 +Potassium channel regulator activity 0.4000768677053244 0.5208456480939417 0.6024743006782187 1.0 1.0 11 O43768,P31749 2 +Abc type transporter activity 0.4098718358862908 0.5184907841855735 0.6041158883870943 1.0 1.0 10 Q9HD20 1 +Heparin binding 0.3779786305234506 0.5178190462501985 0.6045845282838913 1.0 1.0 15 P10586,O14737,P51858 3 +Spectrin binding 0.4345233955242902 0.5121833864957347 0.6085226692294448 1.0 1.0 7 Q13561,P35611 2 +Scaffold protein binding 0.3512412551002296 0.5097887285112965 0.6101994831416713 1.0 1.0 19 P12956,Q9UQB8,P08670,P07602,Q16543,Q8IWS0,Q9Y4P1 7 +Nadp binding 0.3577418451463335 0.5024757653811944 0.6153328954673711 1.0 1.0 18 Q14739,Q13423,P16435 3 +Microtubule binding 0.3031025537095952 0.500853236027149 0.6164744160190563 1.0 1.0 79 P07197,Q2M1P5,O60313,Q96ED9,P50570,P42704,Q7Z4H7,P41208,Q9BSJ2,O75381,Q06787,Q96TC7,P33176,O00429,O60333,Q08379,Q8NBT2,Q96DB5,P15311,Q9H6D7,Q14203,P25054,Q9UH99,Q9H6H4,Q15555,Q15058,Q9UPN3 27 +Chemoattractant activity 0.4662121505944536 0.4991346990838108 0.6176844940982369 1.0 1.0 5 P09429,P14174 2 +Sterol transfer activity 0.4978582313693034 0.4920832332811697 0.6226605046265363 1.0 1.0 4 P30536 1 +Calmodulin dependent protein kinase activity 0.6969517608760027 0.4849160296357584 0.627735911245628 1.0 1.0 2 Q13555 1 +Mhc class i protein binding 0.4096258109043584 0.4724621705337785 0.6365969374416434 1.0 1.0 9 Q03518 1 +Udp glycosyltransferase activity 0.35947923147915 0.4705755987804674 0.6379438362859509 1.0 1.0 17 Q10472,Q10471,P46976,P13807,Q16739,O15294 6 +Dna directed dna polymerase activity 0.4170107877845519 0.4372642683173521 0.661919705600448 1.0 1.0 7 Q9NRG0 1 +N methyltransferase activity 0.3377565245715166 0.429356945057309 0.6676634814946909 1.0 1.0 25 Q03164,Q8WTS6,O60678,Q6P2P2 4 +Lipid transfer activity 0.4078881371690784 0.4283483715067553 0.6683975068682411 1.0 1.0 8 P30536 1 +N6 methyladenosine containing rna binding 0.4202242873720769 0.4249936860353204 0.6708412775240968 1.0 1.0 6 Q9H6S0,P22626,Q7Z739 3 +Oxidoreductase activity acting on nad p h 0.3423589384583133 0.4197710022103721 0.6746527504294582 1.0 1.0 32 Q13423,P03886,O96000,P16435,O43676,O95831 6 +Lys63 specific deubiquitinase activity 0.6747558449245383 0.4190211021460359 0.6752007102991924 1.0 1.0 2 O00487 1 +Copper ion binding 0.397323768119265 0.4156406936045738 0.6776729445269458 1.0 1.0 9 O60888,P00403 2 +Low density lipoprotein particle receptor binding 0.3792572245816425 0.4135425363089329 0.6792091645568683 1.0 1.0 11 P30533,P10909,Q14696 3 +Thiol oxidase activity 0.5431758567464638 0.4110211609434022 0.6810570182482407 1.0 1.0 3 Q6ZRP7 1 +Molecular function activator activity 0.3590729510576322 0.4059436811359558 0.6847839818182728 1.0 1.0 15 P31749,Q96KC8 2 +Nadh dehydrogenase activity 0.3327142141100969 0.401099687398111 0.6883467309931013 1.0 1.0 24 O43676,O95831,O96000,P03886 4 +Lysine n methyltransferase activity 0.3666612410805823 0.3997020578210679 0.689375976269168 1.0 1.0 12 Q03164 1 +Histone lysine n methyltransferase activity 0.3666612410805823 0.3997020578210679 0.689375976269168 1.0 1.0 12 Q03164 1 +Glucocorticoid receptor binding 0.6676531518200698 0.3988555467140633 0.6899996455092514 1.0 1.0 2 Q02790 1 +Flippase activity 0.5364120781527684 0.3908921084316349 0.6958769873911044 1.0 1.0 3 Q9NV96,P08183 2 +Floppase activity 0.5364120781527681 0.3908921084316341 0.695876987391105 1.0 1.0 3 Q96AA3,P08183 2 +Cxcr chemokine receptor binding 0.6632139686297768 0.3864918695489467 0.6991324228957629 1.0 1.0 2 Q96J02 1 +Sh3 domain binding 0.329109421602441 0.3840529715436137 0.7009391867467791 1.0 1.0 23 O75525,Q9NZQ3,P50570,Q07666,Q96D71,Q96PU8,Q16204 7 +N acyltransferase activity 0.3325395703422914 0.3825841422331696 0.7020281299729652 1.0 1.0 19 Q96QD8,Q86UY6,Q96G23 3 +Chemokine receptor binding 0.434325373374589 0.3814287214494625 0.7028851523373345 1.0 1.0 5 Q96J02,P48681 2 +Nadph binding 0.4339799143923238 0.3802113086571519 0.7037885653945428 1.0 1.0 5 Q14739 1 +Glycosyltransferase activity 0.3366014762662763 0.3684315224215373 0.7125514964669972 1.0 1.0 50 P04843,Q68CQ7,Q13126,Q2TAA5,Q9BT22,Q10472,Q8IXJ6,Q9Y2G5,Q06203,Q16739,P43490,O15294 12 +Sodium ion binding 0.6552234388872495 0.364716294236413 0.715323194202375 1.0 1.0 2 P05023 1 +Calcium ion transmembrane transporter activity 0.3577549623659813 0.3631298636293537 0.7165078771027202 1.0 1.0 13 P16615,P98194,Q9HC07 3 +Nad binding 0.3346180764758307 0.3619320849255479 0.7174027827422527 1.0 1.0 32 Q8IXJ6,Q13423,Q8NBZ7 3 +Solute cation symporter activity 0.3918302461501903 0.3598078619061401 0.7189908234745519 1.0 1.0 8 Q96QD8,Q9Y6M7 2 +Sterol transporter activity 0.3828636281608072 0.3512397442034072 0.7254084956239137 1.0 1.0 9 P30536 1 +Protein membrane adaptor activity 0.3799817376242206 0.3387488287776353 0.7347989530429291 1.0 1.0 9 P12270,Q8WXH0,P35579,O94901 4 +Pre mirna binding 0.4215047393364853 0.337185214793998 0.735977282241099 1.0 1.0 5 O75569,Q9UPY3,P62826,Q9H2U1 4 +Adenylyltransferase activity 0.3967754662143097 0.3351011357072472 0.7375487961726779 1.0 1.0 6 Q8NFF5 1 +Quaternary ammonium group binding 0.3540024234072961 0.3342784160753804 0.7381694760638553 1.0 1.0 12 O43633,P21796 2 +Dna binding bending 0.4205161030115447 0.3338562126104477 0.7384880630334636 1.0 1.0 5 P09429 1 +Hexosyltransferase activity 0.3323628525385081 0.3287653983242767 0.742333018637714 1.0 1.0 36 P04843,Q10472,Q13126,Q2TAA5,Q9BT22,P13807,Q9Y2G5,P46977,P46976,Q10471,Q16739,O15294 12 +Symporter activity 0.3702131792757811 0.3287520685859761 0.7423430947247516 1.0 1.0 10 Q96QD8,Q9Y6M7 2 +Calmodulin binding 0.3323539787753597 0.3193480601662912 0.7494625922695621 1.0 1.0 40 Q13813,P35611,P31749,P35612,Q08209,Q7Z406,O43815,Q13555,P35580,Q15075,Q9UEY8,P35579,P32929,Q01844,Q01082 15 +Protein phosphatase binding 0.3301646796034949 0.3065387455529155 0.7591944840418268 1.0 1.0 38 Q86XL3,O43768,P78318,Q9UJX4,P35269 5 +Sphingolipid binding 0.3835305922192974 0.3038073561535404 0.7612746620838993 1.0 1.0 7 P21796,P45880 2 +Acidic amino acid transmembrane transporter activity 0.4376665679597151 0.2964776580876755 0.7668653266879166 1.0 1.0 4 Q15758,O75746,Q9UJS0 3 +L aspartate transmembrane transporter activity 0.4376665679597151 0.2964776580876755 0.7668653266879166 1.0 1.0 4 Q15758,O75746,Q9UJS0 3 +Transferrin receptor binding 0.5016002937722566 0.2946587319188207 0.7682545913018826 1.0 1.0 3 O60749 1 +Heat shock protein binding 0.3272192487398238 0.2933827724627886 0.7692295919864853 1.0 1.0 51 P55011,O75937,O60884,P12270,P46379,P11142,P06493,P48723,Q02790,P23396,P42858,Q16543,P49815,Q07812,Q99543 15 +Cytokine activity 0.3794096879721771 0.2884372058428301 0.7730120911537597 1.0 1.0 7 P43490,P14174 2 +Molecular function inhibitor activity 0.3426656950758761 0.2850324632562591 0.7756192709765308 1.0 1.0 13 Q9NWR8,P62942,O43768 3 +Glucose binding 0.3823926591345202 0.2835119372178519 0.7767844323201196 1.0 1.0 6 P13807,P52789,P11413 3 +Camp dependent protein kinase inhibitor activity 0.6229653743711212 0.2834664212033291 0.7768193184672998 1.0 1.0 2 P10644 1 +Carboxypeptidase activity 0.3522819209723384 0.2833867203717141 0.7768804069504536 1.0 1.0 11 P42785 1 +Metal dependent deubiquitinase activity 0.3777469477240117 0.2823087343639891 0.7777067888013418 1.0 1.0 7 Q92905,O00487,O15372,P51665 4 +Lipoprotein particle receptor binding 0.3430418866915276 0.2798352744364253 0.7796038873277218 1.0 1.0 12 P30533,P10909,Q14696 3 +Signaling receptor binding 0.3141819425291113 0.2647123742303926 0.791231044201369 1.0 1.0 191 Q9Y4E8,P62942,Q9Y4G8,Q9H2J4,P46379,P30533,O43768,Q9BQE5,P50570,O00170,P07942,Q00013,P12814,Q9Y5X3,O75381,Q9NUQ9,P10909,O75312,Q9NZ08,Q9UNH7,Q8WXW3,P06576,O43707,Q07021,P43490,Q15648,Q03518,Q9BY67,Q99584,Q96D09,Q13501,Q92990,P07237,O60749,O00159,P48681,Q99996,Q15276,P14174,Q96RT1,Q9UMX5,P35609,Q9Y2I1,P0DP25,P26583,O14641,P35579,P09429,P51858,Q96QK1,Q92896 51 +Phosphatase binding 0.3251635326754036 0.2642866835582995 0.7915590205836689 1.0 1.0 47 Q86XL3,O43768,P78318,Q9NX63,P49815,Q9UJX4,P35269 7 +G quadruplex rna binding 0.4885378798013938 0.262027309106711 0.7933003879209748 1.0 1.0 3 Q9H2U1 1 +Double stranded telomeric dna binding 0.398121494753363 0.2619029647711985 0.7933962538264179 1.0 1.0 5 P12956 1 +Adp binding 0.3134662560654081 0.2605052707040717 0.7944740501976781 1.0 1.0 19 Q8NI60,P35580,Q03518 3 +Cyclin dependent protein kinase activity 0.3609206637723319 0.2593925927705512 0.7953323442998643 1.0 1.0 9 P24941,P11802,P21127,P06493 4 +Carboxy lyase activity 0.3372589421337364 0.2581140533899969 0.7963188859445096 1.0 1.0 13 Q8NBZ7,P38435,P06132 3 +Flavin adenine dinucleotide binding 0.315487559076809 0.2579433164905739 0.7964506539730232 1.0 1.0 27 Q15067,Q15392,O15254,P16435,O95831 5 +Purine nucleotide transmembrane transporter activity 0.3625607159949648 0.2442447670281497 0.8070412576375037 1.0 1.0 8 Q8TB61 1 +Map kinase activity 0.4804618117229231 0.2428762609374652 0.8081012560517 1.0 1.0 3 P28482,P27361 2 +Cyclin dependent protein serine threonine kinase regulator activity 0.3701530599966507 0.2420328832674934 0.8087546834135857 1.0 1.0 6 P11802,P20248,O94992 3 +Single stranded dna endodeoxyribonuclease activity 0.4130885401243551 0.2288648886270711 0.8189739311087634 1.0 1.0 4 Q9Y2C4,P18887,Q92878 3 +Cytoskeletal anchor activity 0.3519616671367096 0.2242462147813856 0.8225657247980873 1.0 1.0 9 Q9UQB8 1 +Electron transfer activity 0.3165965950162664 0.2190291431705882 0.8266273459361106 1.0 1.0 54 Q9UDW1,P00403,P03886,O96000,P16435,O43676,P14406 7 +Cyclin binding 0.3289451614379163 0.2179468359551708 0.8274705343626982 1.0 1.0 13 P12956,Q9BWF3,P06493,Q96JB5,P11802 5 +Amino acid transmembrane transporter activity 0.3352481130564766 0.2078513409184748 0.8353450436548533 1.0 1.0 11 P30825 1 +Secondary active transmembrane transporter activity 0.3001365156371271 0.2002962524780245 0.8412488932548541 1.0 1.0 22 Q9UBX3,Q96QD8,Q9Y6M7 3 +O acetyltransferase activity 0.5815329979283874 0.1961637869305251 0.8444819711981824 1.0 1.0 2 Q8NF37 1 +O palmitoyltransferase activity 0.5788694880142116 0.1912432352868524 0.8483350318161604 1.0 1.0 2 P23786 1 +Carnitine o acyltransferase activity 0.5788694880142116 0.1912432352868524 0.8483350318161604 1.0 1.0 2 P23786 1 +Phosphatidylinositol bisphosphate binding 0.3115483488608092 0.1880585015360137 0.8508307915984907 1.0 1.0 17 Q13045,Q9BPX3,Q5MNZ6,P35609,Q9Y5X3 5 +Hsp90 protein binding 0.3060353270456826 0.1836202212644552 0.854311398571133 1.0 1.0 18 P55011,P31948,O95801,P23396,Q16543,P49815 6 +Acylglycerol o acyltransferase activity 0.3671373658422134 0.1745143456095692 0.8614612575894429 1.0 1.0 5 Q8NF37,Q8NCC3,Q96N66 3 +Translation repressor activity 0.3330155571047013 0.1732105849793266 0.8624859037882833 1.0 1.0 10 Q14011,Q9BPZ3,Q5PRF9,P00374 4 +Phosphatidylinositol 5 phosphate binding 0.3879182706544107 0.1684699181995416 0.8662136072090585 1.0 1.0 4 Q9Y5X3,Q9NS86,A1X283 3 +Phosphatidylinositol 3 4 5 trisphosphate binding 0.3280844547125618 0.1546937839253205 0.8770627307118029 1.0 1.0 10 P31749 1 +Carbohydrate derivative transmembrane transporter activity 0.3319142177361651 0.1512751616072458 0.8797586619464413 1.0 1.0 9 Q8TB61 1 +Mitochondrial ribosome binding 0.3564683809613014 0.1480374355626832 0.8823132244098713 1.0 1.0 5 Q07021 1 +Oxidoreductase activity acting on a sulfur group of donors 0.2952039916419051 0.1440063094768708 0.8854954873298355 1.0 1.0 25 P78417 1 +Lysine acetylated histone binding 0.3092481935322848 0.1432835568712046 0.8860662415495866 1.0 1.0 15 Q03164 1 +17 beta hydroxysteroid dehydrogenase nadpplus activity 0.5460195324060442 0.1375411284074787 0.8906030858649459 1.0 1.0 2 Q8NBQ5 1 +Amp binding 0.3348148148148177 0.1365426423338721 0.8913923164854878 1.0 1.0 6 P08237,P54619,P06737,Q01813,P17858 5 +Lamin binding 0.3301018761860582 0.1336910399296627 0.8936468906571313 1.0 1.0 8 Q14739,Q9UH99,O94901 3 +2 oxoglutarate dependent dioxygenase activity 0.2907995062533382 0.1290502991752773 0.8973178485634954 1.0 1.0 19 Q8IVL6,Q9UPP1 2 +Beta catenin binding 0.2954946390865833 0.1273682438964022 0.8986489492033001 1.0 1.0 18 Q9P1Z2,Q9Y297,P25054,Q86X55 4 +Aminophospholipid flippase activity 0.5362533293873997 0.1240436919758761 0.9012806809891576 1.0 1.0 2 Q9NV96 1 +Glycerophospholipid flippase activity 0.5362533293873997 0.1240436919758761 0.9012806809891576 1.0 1.0 2 P08183 1 +Phosphatidylethanolamine flippase activity 0.5362533293873997 0.1240436919758761 0.9012806809891576 1.0 1.0 2 P08183 1 +Beta 2 adrenergic receptor binding 0.5220479431784625 0.1063706210842312 0.9152883017857928 1.0 1.0 2 P46934 1 +Immunoglobulin binding 0.5220479431784625 0.1063706210842312 0.9152883017857928 1.0 1.0 2 P17931 1 +Acetylcholine receptor binding 0.522047943178462 0.1063706210842306 0.9152883017857932 1.0 1.0 2 O15258 1 +Isopeptidase activity 0.3168149827592982 0.1020239757321281 0.9187376444968004 1.0 1.0 9 O00303,P51665,O15372,Q92905,O00487 5 +K48 linked polyubiquitin modification dependent protein binding 0.3317174639325236 0.0942347435137075 0.9249226862294329 1.0 1.0 5 Q04323 1 +Histone h3 tri di monomethyl lysine 4 demethylase activity 0.5102101213376811 0.0933601616515839 0.9256174386376969 1.0 1.0 2 Q9H6W3 1 +Translation initiation factor binding 0.2883564683168321 0.0914663307939201 0.9271220581968528 1.0 1.0 18 O75312,Q06787,Q9Y4P3,P55010 4 +Microtubule motor activity 0.2781546483675159 0.0912195456807834 0.9273181444931032 1.0 1.0 20 P33176,O60333,Q2M1P5,Q8NCM8,Q15058,Q9UQE7 6 +Integrin binding 0.2812463777963374 0.0895543919883719 0.9286413286311276 1.0 1.0 22 P35609,Q9Y2I1,P35579,O43707,P07942,P12814 6 +1 alkyl 2 acetylglycerophosphocholine esterase activity 0.5013317549570955 0.0845854335236755 0.932590979925964 1.0 1.0 2 P68402 1 +Sphingolipid transporter activity 0.4977804084048612 0.0813035188900376 0.9352005755876676 1.0 1.0 2 P08183 1 +Phosphatidylcholine transporter activity 0.4977804084048612 0.0813035188900376 0.9352005755876676 1.0 1.0 2 P08183 1 +Guanyl nucleotide exchange factor activity 0.2955747665414256 0.0799730158665901 0.936258717432024 1.0 1.0 35 P80303,P29692,Q14C86,Q9Y4G8 4 +S adenosylmethionine dependent methyltransferase activity 0.3002591411867923 0.0798913969002352 0.936323632238074 1.0 1.0 44 Q96P11,Q8WTS6,Q03164,O60678,O60725,Q6P2P2 6 +Extracellular matrix structural constituent 0.3790840066557162 0.0741084785610476 0.9409240688987648 1.0 1.0 3 P07942 1 +Epidermal growth factor receptor binding 0.308148148148151 0.0726210999403493 0.9421076357271296 1.0 1.0 6 Q92600,O60749,P18085,P62993,Q13596 5 +Potassium ion transmembrane transporter activity 0.3338867986996721 0.0716496837684733 0.9428806997187622 1.0 1.0 4 P55011 1 +Ubiquinone binding 0.4800236756436896 0.066751874021878 0.946779236870272 1.0 1.0 2 P21912 1 +Cytoskeletal motor activity 0.2894557204312544 0.0663266319579717 0.9471177806683456 1.0 1.0 31 P33176,Q7Z406,O60333,O00159,Q2M1P5,P35580,P35579,Q8NCM8,Q15058,P60660,Q9UQE7 11 +Mitogen activated protein kinase binding 0.3033111397455985 0.0593507839760715 0.9526727126080344 1.0 1.0 7 Q96JB5 1 +Double stranded rna adenosine deaminase activity 0.4687777448949456 0.059039353691717 0.9529207630504142 1.0 1.0 2 Q9NZI8 1 +Histone h3 methyl lysine 4 demethylase activity 0.3116113744075747 0.0585319516466629 0.9533249123801804 1.0 1.0 5 P29375,Q9H6W3,Q8NB78,O60341 4 +Lysophospholipid acyltransferase activity 0.3175475197471352 0.0511798884065671 0.9591821775654604 1.0 1.0 4 Q96N66,Q8NF37 2 +Importin alpha family protein binding 0.2920776692122314 0.0410216065958768 0.9672786707856568 1.0 1.0 6 Q08379 1 +Ionotropic glutamate receptor binding 0.2907804413233583 0.0386988348719551 0.9691305023525384 1.0 1.0 6 Q13501 1 +Tumor necrosis factor receptor binding 0.3309650680876245 0.0376873878010357 0.9699369319306392 1.0 1.0 3 Q9NXR7,P42224 2 +Tumor necrosis factor receptor superfamily binding 0.3309650680876245 0.0376873878010357 0.9699369319306392 1.0 1.0 3 Q9NXR7,P42224 2 +Atp dependent chromatin remodeler activity 0.2965047393364892 0.0363672095362492 0.9709895598744192 1.0 1.0 5 Q9H4L7,P28370,Q12873,Q9HCK8 4 +Opsonin binding 0.3146832445233803 0.0302267301060131 0.9758862307259252 1.0 1.0 3 Q07021,P35232 2 +Complement binding 0.3146832445233803 0.0302267301060131 0.9758862307259252 1.0 1.0 3 Q07021,P35232 2 +Neurotrophin receptor binding 0.307874481941973 0.0276903952831522 0.9779090842214806 1.0 1.0 3 P19174,P62993 2 +Neurotrophin trk receptor binding 0.307874481941973 0.0276903952831522 0.9779090842214806 1.0 1.0 3 P19174,P62993 2 +Polysaccharide binding 0.3577981651376221 0.0258076519632964 0.9794107584988452 1.0 1.0 2 P22413 1 +Bhlh transcription factor binding 0.3572062740455832 0.0257589828348717 0.979449577939671 1.0 1.0 2 O60341 1 +Single stranded dna exodeoxyribonuclease activity 0.2869619836046243 0.0243503174657251 0.9805731774791736 1.0 1.0 5 Q9UQ84 1 +Signal recognition particle binding 0.2814814814814845 0.0230340235709538 0.9816231332581218 1.0 1.0 6 Q9GZP9,O76094,Q9BUN8,Q9UHB9,P49458 5 +Mutlalpha complex binding 0.280047365304909 0.0202456966405231 0.9838473746972048 1.0 1.0 3 P43246,P52701 2 +Mismatch repair complex binding 0.280047365304909 0.0202456966405231 0.9838473746972048 1.0 1.0 3 P43246,P52701 2 +Dna insertion or deletion binding 0.280130293159602 0.0180538956151342 0.9855958579191546 1.0 1.0 4 P43246,P52701,P20585 3 +Phosphoric ester hydrolase activity 0.2773876316867418 0.0113776539197839 0.990922141455993 1.0 1.0 69 Q9NPH0,Q7Z4H3,P09601,Q9Y3Z3,Q08209,O95677,Q9NX62,Q9P0J1,Q9BRF8,Q969T7,Q8N2A8,P10586 12 +Sh2 domain binding 0.2806774923042861 0.0062933275682192 0.9949786842429464 1.0 1.0 9 Q96T51,Q13501,Q07666,A1X283 4 +Protein disaggregase activity 0.2555522653242476 0.0050140714396416 0.9959993665748168 1.0 1.0 4 Q9UN37,P0DMV9,P11142 3 diff --git a/msigdb_gomf/selections.json b/msigdb_gomf/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..5b49c09175eecaf6edd0f2a854ec259c34c053bd --- /dev/null +++ b/msigdb_gomf/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1 4 alpha oligoglucan phosphorylase activity", "1 acylglycerophosphocholine o acyltransferase activity", "1 alkyl 2 acetylglycerophosphocholine esterase activity", "1 phosphatidylinositol 3 kinase activity", "1 phosphatidylinositol 4 kinase activity", "1 phosphatidylinositol 4 phosphate 3 kinase activity", "1 phosphatidylinositol 4 phosphate 5 kinase activity", "1 phosphatidylinositol binding", "14 3 3 protein binding", "17 beta hydroxysteroid dehydrogenase nadplus activity", "17 beta hydroxysteroid dehydrogenase nadpplus activity", "2 acylglycerol 3 phosphate o acyltransferase activity", "2 acylglycerol o acyltransferase activity", "2 iron 2 sulfur cluster binding", "2 oxoglutarate dependent dioxygenase activity", "3 5 dna helicase activity", "3 5 exodeoxyribonuclease activity", "3 5 exonuclease activity", "3 beta hydroxy delta5 steroid dehydrogenase activity", "3 hydroxyacyl coa dehydratase activity", "3 hydroxyacyl coa dehydrogenase activity", "3 phosphoadenosine 5 phosphosulfate binding", "4 iron 4 sulfur cluster binding", "5 3 dna helicase activity", "5 3 exodeoxyribonuclease activity", "5 3 exonuclease activity", "5 deoxyribose 5 phosphate lyase activity", "5s rrna binding", "7s rna binding", "7sk snrna binding", "Abc type glutathione s conjugate transporter activity", "Abc type transporter activity", "Abc type xenobiotic transporter activity", "Acetyl coa c acetyltransferase activity", "Acetyl coa c acyltransferase activity", "Acetyl coa hydrolase activity", "Acetylcholine receptor binding", "Acetylgalactosaminyltransferase activity", "Acetylglucosaminyltransferase activity", "Acetyltransferase activity", "Acid amino acid ligase activity", "Acid phosphatase activity", "Acid thiol ligase activity", "Acidic amino acid transmembrane transporter activity", "Actin binding", "Actin filament binding", "Actin monomer binding", "Actinin binding", "Active ion transmembrane transporter activity", "Active transmembrane transporter activity", "Activin binding", "Acyl carnitine transmembrane transporter activity", "Acyl coa binding", "Acyl coa dehydrogenase activity", "Acyl coa oxidase activity", "Acylglycerol lipase activity", "Acylglycerol o acyltransferase activity", "Acyltransferase activity", "Acyltransferase acyl groups converted into alkyl on transfer", "Adenosine deaminase activity", "Adenyl nucleotide binding", "Adenyl nucleotide exchange factor activity", "Adenylate cyclase binding", "Adenylate kinase activity", "Adenylyltransferase activity", "Adp binding", "Adp ribose diphosphatase activity", "Adp transmembrane transporter activity", "Adrenergic receptor binding", "Alanine transmembrane transporter activity", "Alcohol binding", "Alcohol dehydrogenase activity zinc dependent", "Alcohol dehydrogenase nad p plus activity", "Alcohol dehydrogenase nadpplus activity", "Aldehyde dehydrogenase nad p plus activity", "Aldehyde lyase activity", "Alditol nadpplus 1 oxidoreductase activity", "Aldo keto reductase nadp activity", "Alkali metal ion binding", "Alpha actinin binding", "Alpha catenin binding", "Alpha glucosidase activity", "Alpha tubulin binding", "Amide binding", "Amide transmembrane transporter activity", "Amidine lyase activity", "Amino acid binding", "Amino acid cation symporter activity", "Amino acid proton symporter activity", "Amino acid sodium symporter activity", "Amino acid transmembrane transporter activity", "Aminoacyl trna editing activity", "Aminoacylase activity", "Aminopeptidase activity", "Aminophospholipid flippase activity", "Ammonium transmembrane transporter activity", "Amp activated protein kinase activity", "Amp binding", "Amyloid beta binding", "Anaphase promoting complex binding", "Androgen receptor binding", "Androstan 3 alpha 17 beta diol dehydrogenase activity", "Anion cation symporter activity", "Anion channel activity", "Anion sodium symporter activity", "Anion transmembrane transporter activity", "Ankyrin binding", "Ankyrin repeat binding", "Annealing activity", "Antigen binding", "Antioxidant activity", "Antiporter activity", "Apolipoprotein a i binding", "Apolipoprotein binding", "Apolipoprotein receptor binding", "Arachidonate coa ligase activity", "Arginine binding", "Armadillo repeat domain binding", "Aromatic amino acid transmembrane transporter activity", "Arp2 3 complex binding", "Arrestin family protein binding", "Aryl hydrocarbon receptor binding", "Arylesterase activity", "Arylsulfatase activity", "Aspartic endopeptidase activity intramembrane cleaving", "Aspartic type endopeptidase inhibitor activity", "Aspartic type peptidase activity", "Atp dependent activity", "Atp dependent activity acting on dna", "Atp dependent activity acting on rna", "Atp dependent chromatin remodeler activity", "Atp dependent dna dna annealing activity", "Atp dependent peptidase activity", "Atp dependent protein binding", "Atp hydrolysis activity", "Atp transmembrane transporter activity", "Atpase activator activity", "Atpase binding", "Atpase coupled cation transmembrane transporter activity", "Atpase coupled inorganic anion transmembrane transporter activity", "Atpase coupled intramembrane lipid transporter activity", "Atpase coupled ion transmembrane transporter activity", "Atpase coupled lipid transmembrane transporter activity", "Atpase coupled transmembrane transporter activity", "Atpase inhibitor activity", "Atpase regulator activity", "Axon guidance receptor activity", "Azole transmembrane transporter activity", "Basal transcription machinery binding", "Basic amino acid transmembrane transporter activity", "Benzodiazepine receptor activity", "Beta 1 3 galactosyltransferase activity", "Beta 2 adrenergic receptor binding", "Beta 2 microglobulin binding", "Beta catenin binding", "Beta galactosidase activity", "Beta n acetylhexosaminidase activity", "Beta tubulin binding", "Bh domain binding", "Bh3 domain binding", "Bhlh transcription factor binding", "Bicarbonate transmembrane transporter activity", "Bile acid binding", "Biotin binding", "Box h aca snorna binding", "Branched chain amino acid transmembrane transporter activity", "Bubble dna binding", "C acetyltransferase activity", "C acyltransferase activity", "C methyltransferase activity", "C palmitoyltransferase activity", "C x c chemokine binding", "C x3 c chemokine binding", "C2h2 zinc finger domain binding", "C3hc4 type ring finger domain binding", "C4 dicarboxylate transmembrane transporter activity", "Cadherin binding", "Cadherin binding involved in cell cell adhesion", "Calcium activated cation channel activity", "Calcium cation antiporter activity", "Calcium channel inhibitor activity", "Calcium channel regulator activity", "Calcium dependent cysteine type endopeptidase activity", "Calcium dependent phospholipid binding", "Calcium dependent protein binding", "Calcium dependent protein kinase activity", "Calcium dependent protein serine threonine phosphatase activity", "Calcium independent phospholipase a2 activity", "Calcium ion binding", "Calcium ion transmembrane transporter activity", "Calmodulin binding", "Calmodulin dependent protein kinase activity", "Calmodulin dependent protein phosphatase activity", "Camp binding", "Camp dependent protein kinase activity", "Camp dependent protein kinase inhibitor activity", "Camp dependent protein kinase regulator activity", "Camp response element binding", "Carbohydrate binding", "Carbohydrate derivative transmembrane transporter activity", "Carbohydrate kinase activity", "Carbohydrate phosphatase activity", "Carbon carbon lyase activity", "Carbon nitrogen ligase activity with glutamine as amido n donor", "Carbon nitrogen lyase activity", "Carbon oxygen lyase activity", "Carbon sulfur lyase activity", "Carbonyl reductase nadph activity", "Carboxy lyase activity", "Carboxylic acid binding", "Carboxylic ester hydrolase activity", "Carboxypeptidase activity", "Card domain binding", "Cardiolipin binding", "Cargo adaptor activity", "Cargo receptor activity", "Carnitine o acyltransferase activity", "Catalytic activity acting on a glycoprotein", "Catalytic activity acting on a nucleic acid", "Catalytic activity acting on a rrna", "Catalytic activity acting on a trna", "Catalytic activity acting on dna", "Catalytic activity acting on rna", "Cation cation antiporter activity", "Cation channel activity", "Cation chloride symporter activity", "Cation transmembrane transporter activity", "Ccr chemokine receptor binding", "Ccr3 chemokine receptor binding", "Ccr5 chemokine receptor binding", "Cdp alcohol phosphatidyltransferase activity", "Cell adhesion mediator activity", "Cell adhesion molecule binding", "Cell adhesive protein binding involved in bundle of his cell purkinje myocyte communication", "Cell cell adhesion mediator activity", "Cell matrix adhesion mediator activity", "Centromeric dna binding", "Ceramide binding", "Cgmp binding", "Channel activator activity", "Channel inhibitor activity", "Channel regulator activity", "Chaperone binding", "Chemoattractant activity", "Chemokine binding", "Chemokine receptor binding", "Chemorepellent activity", "Chitin binding", "Chloride channel inhibitor activity", "Chloride channel regulator activity", "Chloride ion binding", "Chloride transmembrane transporter activity", "Cholesterol binding", "Chondroitin sulfate binding", "Chromatin binding", "Chromatin dna binding", "Chromatin insulator sequence binding", "Chromo shadow domain binding", "Cis regulatory region sequence specific dna binding", "Cis trans isomerase activity", "Class i dna apurinic or apyrimidinic site endonuclease activity", "Clathrin binding", "Clathrin heavy chain binding", "Clathrin light chain binding", "Co smad binding", "Coa hydrolase activity", "Coa transferase activity", "Cobalamin binding", "Collagen binding", "Collagen binding involved in cell matrix adhesion", "Complement binding", "Complement component c1q complex binding", "Complement component c3b binding", "Copper chaperone activity", "Copper ion binding", "Core promoter sequence specific dna binding", "Coreceptor activity", "Coreceptor activity involved in wnt signaling pathway", "Coreceptor activity involved in wnt signaling pathway planar cell polarity pathway", "Cullin family protein binding", "Cuprous ion binding", "Cxcr chemokine receptor binding", "Cyclase activity", "Cyclase regulator activity", "Cyclic nucleotide binding", "Cyclic nucleotide dependent protein kinase activity", "Cyclic nucleotide phosphodiesterase activity", "Cyclin binding", "Cyclin dependent protein kinase activity", "Cyclin dependent protein serine threonine kinase activator activity", "Cyclin dependent protein serine threonine kinase inhibitor activity", "Cyclin dependent protein serine threonine kinase regulator activity", "Cyclohydrolase activity", "Cyclosporin a binding", "Cysteine type endopeptidase activity", "Cysteine type endopeptidase inhibitor activity", "Cysteine type endopeptidase inhibitor activity involved in apoptotic process", "Cysteine type endopeptidase regulator activity involved in apoptotic process", "Cysteine type exopeptidase activity", "Cysteine type peptidase activity", "Cytidine deaminase activity", "Cytidylyltransferase activity", "Cytochrome b5 reductase activity acting on nad p h", "Cytokine activity", "Cytokine binding", "Cytokine receptor binding", "Cytoskeletal anchor activity", "Cytoskeletal motor activity", "Cytoskeletal protein binding", "Cytoskeleton nuclear membrane anchor activity", "D loop dna binding", "D threo aldose 1 dehydrogenase activity", "D1 dopamine receptor binding", "Damaged dna binding", "Deacetylase activity", "Dead h box rna helicase binding", "Deaminase activity", "Death domain binding", "Death receptor activity", "Demethylase activity", "Deoxycytidine deaminase activity", "Deoxynucleoside kinase activity", "Deoxyribonuclease activity", "Deoxyribonuclease i activity", "Diacylglycerol binding", "Diacylglycerol kinase activity", "Dicarboxylic acid transmembrane transporter activity", "Dihydropyrimidinase activity", "Dioxygenase activity", "Dipeptidase activity", "Dipeptidyl peptidase activity", "Diphosphotransferase activity", "Disordered domain specific binding", "Disulfide oxidoreductase activity", "Dna apurinic or apyrimidinic site endonuclease activity", "Dna binding bending", "Dna binding transcription activator activity", "Dna binding transcription factor activity", "Dna binding transcription factor binding", "Dna binding transcription repressor activity", "Dna clamp loader activity", "Dna directed dna polymerase activity", "Dna dna annealing activity", "Dna helicase activity", "Dna insertion or deletion binding", "Dna methyltransferase activity", "Dna n glycosylase activity", "Dna polymerase activity", "Dna polymerase binding", "Dna replication origin binding", "Dna secondary structure binding", "Dna topoisomerase activity", "Dna translocase activity", "Dolichyl diphosphooligosaccharide protein glycotransferase activity", "Dolichyl phosphate mannose protein mannosyltransferase activity", "Dopamine receptor binding", "Double stranded methylated dna binding", "Double stranded rna adenosine deaminase activity", "Double stranded rna binding", "Double stranded telomeric dna binding", "Dttp diphosphatase activity", "Dynactin binding", "Dynein complex binding", "Dynein heavy chain binding", "Dynein intermediate chain binding", "Dynein light chain binding", "Dynein light intermediate chain binding", "Dystroglycan binding", "E box binding", "Efflux transmembrane transporter activity", "Electron transfer activity", "Endodeoxyribonuclease activity", "Endodeoxyribonuclease activity producing 5 phosphomonoesters", "Endonuclease activity", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 3 phosphomonoesters", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Endopeptidase activator activity", "Endopeptidase activity", "Endopeptidase regulator activity", "Endoribonuclease activity", "Endoribonuclease activity producing 3 phosphomonoesters", "Endoribonuclease activity producing 5 phosphomonoesters", "Enoyl coa hydratase activity", "Enzyme activator activity", "Enzyme inhibitor activity", "Enzyme regulator activity", "Ephrin receptor activity", "Ephrin receptor binding", "Epidermal growth factor receptor binding", "Epoxide hydrolase activity", "Er retention sequence binding", "Erbb 3 class receptor binding", "Estradiol 17 beta dehydrogenase activity", "Estrogen receptor binding", "Ether hydrolase activity", "Eukaryotic initiation factor 4e binding", "Exodeoxyribonuclease activity", "Exogenous protein binding", "Exonuclease activity", "Exonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Exopeptidase activity", "Exoribonuclease activity", "Exoribonuclease activity producing 5 phosphomonoesters", "Extracellular matrix binding", "Extracellular matrix constituent conferring elasticity", "Extracellular matrix structural constituent", "Fad binding", "Fatty acid binding", "Fatty acid derivative binding", "Fatty acid ligase activity", "Fatty acid synthase activity", "Fatty acid transmembrane transporter activity", "Fatz binding", "Ferric iron binding", "Ferrous iron binding", "Fibroblast growth factor binding", "Fibronectin binding", "Filamin binding", "Fk506 binding", "Flap endonuclease activity", "Flavin adenine dinucleotide binding", "Flippase activity", "Floppase activity", "Fmn binding", "Folic acid binding", "Folic acid transmembrane transporter activity", "Four way junction dna binding", "Four way junction helicase activity", "Frizzled binding", "Fructose 2 6 bisphosphate 2 phosphatase activity", "Fructose 6 phosphate binding", "Fructose binding", "Fucosyltransferase activity", "G protein activity", "G protein alpha subunit binding", "G protein beta gamma subunit complex binding", "G protein beta subunit binding", "G protein coupled glutamate receptor binding", "G protein coupled opioid receptor activity", "G protein coupled receptor activity", "G protein coupled receptor binding", "G protein coupled serotonin receptor binding", "G quadruplex dna binding", "G quadruplex rna binding", "G rich strand telomeric dna binding", "Gaba receptor binding", "Galactosidase activity", "Galactoside binding", "Galactosyltransferase activity", "Gamma catenin binding", "Gamma tubulin binding", "Ganglioside binding", "Gated channel activity", "Gdp binding", "Gdp dissociation inhibitor activity", "General transcription initiation factor activity", "General transcription initiation factor binding", "Glucocorticoid receptor binding", "Glucose binding", "Glucosidase activity", "Glucosyltransferase activity", "Glucuronosyltransferase activity", "Glutamate receptor binding", "Glutathione disulfide oxidoreductase activity", "Glutathione oxidoreductase activity", "Glutathione peroxidase activity", "Glutathione transferase activity", "Glutathione transmembrane transporter activity", "Glyceraldehyde 3 phosphate dehydrogenase nadplus non phosphorylating activity", "Glycerophospholipid flippase activity", "Glycine binding", "Glycolipid binding", "Glycolipid mannosyltransferase activity", "Glycosaminoglycan binding", "Glycosphingolipid binding", "Glycosyltransferase activity", "Gpi anchor binding", "Gpi linked ephrin receptor activity", "Growth factor activity", "Growth factor binding", "Growth factor receptor binding", "Gtp dependent protein binding", "Gtpase activating protein binding", "Gtpase activator activity", "Gtpase activity", "Gtpase binding", "Gtpase inhibitor activity", "Guanosine diphosphatase activity", "Guanyl nucleotide binding", "Guanyl nucleotide exchange factor activity", "Guanylate kinase activity", "Guanylyltransferase activity", "H4 histone acetyltransferase activity", "Heat shock protein binding", "Helicase activity", "Heme transmembrane transporter activity", "Heparan sulfate proteoglycan binding", "Heparan sulfate sulfotransferase activity", "Heparin binding", "Hexokinase activity", "Hexosaminidase activity", "Hexosyltransferase activity", "High density lipoprotein particle binding", "Histone acetyltransferase binding", "Histone arginine n methyltransferase activity", "Histone binding", "Histone deacetylase activity h3 k14 specific", "Histone deacetylase binding", "Histone deacetylase regulator activity", "Histone h3 di monomethyl lysine 9 demethylase activity", "Histone h3 methyl lysine 36 demethylase activity", "Histone h3 methyl lysine 4 demethylase activity", "Histone h3 methyl lysine 9 demethylase activity", "Histone h3 tri di methyl lysine 27 demethylase activity", "Histone h3 tri di monomethyl lysine 4 demethylase activity", "Histone kinase activity", "Histone lysine n methyltransferase activity", "Histone methyltransferase activity", "Histone methyltransferase activity h3 k36 specific", "Histone methyltransferase activity h3 k4 specific", "Histone methyltransferase activity h3 k9 specific", "Histone methyltransferase activity h4 k20 specific", "Histone methyltransferase binding", "Histone serine kinase activity", "Histone threonine kinase activity", "Hormone activity", "Hormone binding", "Hormone receptor binding", "Hsp70 protein binding", "Hsp90 protein binding", "Hyaluronic acid binding", "Hyalurononglucosaminidase activity", "Hydro lyase activity", "Hydrolase activity acting on acid anhydrides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amidines", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amidines", "Hydrolase activity acting on ester bonds", "Hydrolase activity acting on ether bonds", "Hydrolase activity acting on glycosyl bonds", "Hydrolase activity hydrolyzing n glycosyl compounds", "Hydrolase activity hydrolyzing o glycosyl compounds", "Hydroxymethyl formyl and related transferase activity", "I smad binding", "Icosanoid binding", "Identical protein binding", "Ige binding", "Immunoglobulin binding", "Immunoglobulin receptor binding", "Importin alpha family protein binding", "Inorganic anion exchanger activity", "Inorganic anion transmembrane transporter activity", "Inorganic diphosphatase activity", "Inorganic molecular entity transmembrane transporter activity", "Inorganic phosphate transmembrane transporter activity", "Inositol 1 4 5 trisphosphate 5 phosphatase activity", "Inositol phosphate phosphatase activity", "Inositol polyphosphate 5 phosphatase activity", "Inositol tetrakisphosphate phosphatase activity", "Inositol trisphosphate phosphatase activity", "Insulin binding", "Insulin like growth factor binding", "Insulin like growth factor i binding", "Insulin like growth factor ii binding", "Insulin like growth factor receptor binding", "Insulin receptor binding", "Insulin receptor substrate binding", "Integrin binding", "Interleukin 1 binding", "Interleukin 1 receptor binding", "Interleukin 2 receptor binding", "Interleukin 6 receptor binding", "Intermediate filament binding", "Intracellular calcium activated chloride channel activity", "Intraciliary transport particle b binding", "Intramembrane lipid transporter activity", "Intramolecular oxidoreductase activity", "Intramolecular oxidoreductase activity interconverting aldoses and ketoses", "Intramolecular oxidoreductase activity transposing c c bonds", "Intramolecular transferase activity", "Intramolecular transferase activity phosphotransferases", "Ion gated channel activity", "Ion transmembrane transporter activity", "Ionotropic glutamate receptor binding", "Iron ion binding", "Isocitrate dehydrogenase activity", "Isomerase activity", "Isopeptidase activity", "Isoprenoid binding", "Jun kinase binding", "K48 linked polyubiquitin modification dependent protein binding", "K63 linked polyubiquitin modification dependent protein binding", "Keratin filament binding", "Kinase activator activity", "Kinase activity", "Kinase binding", "Kinase inhibitor activity", "Kinase regulator activity", "Kinesin binding", "Kinetochore binding", "L alanine transmembrane transporter activity", "L amino acid transmembrane transporter activity", "L arginine transmembrane transporter activity", "L ascorbic acid binding", "L aspartate transmembrane transporter activity", "L glutamine transmembrane transporter activity", "L histidine transmembrane transporter activity", "L lactate dehydrogenase activity", "L leucine transmembrane transporter activity", "L lysine transmembrane transporter activity", "L ornithine transmembrane transporter activity", "L serine transmembrane transporter activity", "Lactate dehydrogenase activity", "Lactate transmembrane transporter activity", "Lamin binding", "Laminin 1 binding", "Laminin binding", "Large ribosomal subunit rrna binding", "Lbd domain binding", "Leucine binding", "Leucine zipper domain binding", "Leukotriene c4 synthase activity", "Ligand gated ion channel activity", "Ligase activity", "Ligase activity forming carbon carbon bonds", "Ligase activity forming carbon nitrogen bonds", "Ligase activity forming carbon oxygen bonds", "Ligase activity forming carbon sulfur bonds", "Ligase activity forming phosphoric ester bonds", "Lim domain binding", "Lipase activator activity", "Lipase activity", "Lipase binding", "Lipase inhibitor activity", "Lipid binding", "Lipid kinase activity", "Lipid transfer activity", "Lipid transporter activity", "Lipopolysaccharide binding", "Lipopolysaccharide immune receptor activity", "Lipoprotein particle receptor activity", "Lipoprotein particle receptor binding", "Long chain acyl coa dehydrogenase activity", "Long chain fatty acid binding", "Long chain fatty acid coa ligase activity", "Long chain fatty acid transporter activity", "Long chain fatty acyl coa binding", "Low density lipoprotein particle binding", "Low density lipoprotein particle receptor activity", "Low density lipoprotein particle receptor binding", "Lrr domain binding", "Lyase activity", "Lys48 specific deubiquitinase activity", "Lys63 specific deubiquitinase activity", "Lysine acetylated histone binding", "Lysine n methyltransferase activity", "Lysophosphatidic acid binding", "Lysophosphatidic acid phosphatase activity", "Lysophospholipase activity", "Lysophospholipid acyltransferase activity", "M7g 5 pppn diphosphatase activity", "Macrolide binding", "Macromolecule transmembrane transporter activity", "Magnesium ion binding", "Magnesium ion transmembrane transporter activity", "Malate dehydrogenase activity", "Manganese ion binding", "Manganese ion transmembrane transporter activity", "Mannose binding", "Mannosidase activity", "Mannosyl oligosaccharide 1 2 alpha mannosidase activity", "Mannosyl oligosaccharide mannosidase activity", "Mannosyltransferase activity", "Map kinase activity", "Map kinase kinase activity", "Map kinase kinase kinase activity", "Map kinase phosphatase activity", "Map kinase scaffold activity", "Mdm2 mdm4 family protein binding", "Medium chain fatty acid coa ligase activity", "Membrane insertase activity", "Metal cluster binding", "Metal dependent deubiquitinase activity", "Metal ion proton antiporter activity", "Metal ion transmembrane transporter activity", "Metalloaminopeptidase activity", "Metallocarboxypeptidase activity", "Metallochaperone activity", "Metallodipeptidase activity", "Metalloendopeptidase activity", "Metalloexopeptidase activity", "Metallopeptidase activity", "Methyl cpg binding", "Methylated histone binding", "Mhc class i protein binding", "Mhc class ib protein binding", "Mhc class ii protein complex binding", "Mhc protein binding", "Mhc protein complex binding", "Microfilament motor activity", "Microtubule binding", "Microtubule minus end binding", "Microtubule motor activity", "Microtubule plus end binding", "Minor groove of adenine thymine rich dna binding", "Minus end directed microtubule motor activity", "Mirna binding", "Misfolded protein binding", "Mismatch repair complex binding", "Mismatched dna binding", "Mitochondrial ribosome binding", "Mitochondrion targeting sequence binding", "Mitogen activated protein kinase binding", "Mitogen activated protein kinase kinase binding", "Mitogen activated protein kinase kinase kinase binding", "Mitogen activated protein kinase p38 binding", "Modification dependent protein binding", "Modified amino acid binding", "Modified amino acid transmembrane transporter activity", "Molecular adaptor activity", "Molecular carrier activity", "Molecular function activator activity", "Molecular function inhibitor activity", "Molecular function regulator", "Molecular sequestering activity", "Molecular transducer activity", "Molybdopterin cofactor binding", "Monocarboxylic acid binding", "Monocarboxylic acid transmembrane transporter activity", "Monooxygenase activity", "Monosaccharide binding", "Mrf binding", "Mrna 3 utr au rich region binding", "Mrna 3 utr binding", "Mrna 5 utr binding", "Mrna binding", "Mrna methyltransferase activity", "Muscle alpha actinin binding", "Mutlalpha complex binding", "Myosin binding", "Myosin ii binding", "Myosin v binding", "Myristoyltransferase activity", "N acetylgalactosamine 4 o sulfotransferase activity", "N acetyllactosaminide beta 1 3 n acetylglucosaminyltransferase activity", "N acetyltransferase activity", "N acylsphingosine amidohydrolase activity", "N acyltransferase activity", "N methyltransferase activity", "N6 methyladenosine containing rna binding", "Nad binding", "Nad dependent protein deacetylase activity", "Nad p h oxidase h2o2 forming activity", "Nad p plus nucleosidase activity", "Nad p plus protein arginine adp ribosyltransferase activity", "Nad retinol dehydrogenase activity", "Nadh dehydrogenase activity", "Nadh pyrophosphatase activity", "Nadp binding", "Nadp retinol dehydrogenase activity", "Nadph binding", "Nadplus adp ribosyltransferase activity", "Nadplus binding", "Nadplus kinase activity", "Nadplus nucleosidase activity", "Nedd8 specific protease activity", "Nedd8 transferase activity", "Nerve growth factor binding", "Neurexin family protein binding", "Neuroligin family protein binding", "Neurotransmitter binding", "Neurotransmitter receptor activity", "Neurotransmitter receptor regulator activity", "Neurotransmitter transmembrane transporter activity", "Neurotrophin binding", "Neurotrophin receptor activity", "Neurotrophin receptor binding", "Neurotrophin trk receptor binding", "Neutral amino acid transmembrane transporter activity", "Nf kappab binding", "Nf kappab inducing kinase activity", "Nfat protein binding", "Nitric oxide synthase binding", "Nitric oxide synthase regulator activity", "Nitrite reductase activity", "Non membrane spanning protein tyrosine kinase activity", "Non membrane spanning protein tyrosine phosphatase activity", "Notch binding", "Nuclear export signal receptor activity", "Nuclear import signal receptor activity", "Nuclear localization sequence binding", "Nuclear receptor activity", "Nuclear receptor binding", "Nuclear receptor coactivator activity", "Nuclease activity", "Nucleobase containing compound kinase activity", "Nucleobase containing compound transmembrane transporter activity", "Nucleobase transmembrane transporter activity", "Nucleocytoplasmic carrier activity", "Nucleoside binding", "Nucleoside diphosphatase activity", "Nucleoside diphosphate kinase activity", "Nucleoside kinase activity", "Nucleoside monophosphate kinase activity", "Nucleoside transmembrane transporter activity", "Nucleoside triphosphatase regulator activity", "Nucleoside triphosphate diphosphatase activity", "Nucleosomal dna binding", "Nucleosome binding", "Nucleotidase activity", "Nucleotide diphosphatase activity", "Nucleotide phosphatase activity acting on free nucleotides", "Nucleotide sugar transmembrane transporter activity", "Nucleotide transmembrane transporter activity", "Nucleotidyltransferase activity", "O acetyltransferase activity", "O acyltransferase activity", "O methyltransferase activity", "O palmitoyltransferase activity", "Oleate transmembrane transporter activity", "Oligopeptide binding", "Oligopeptide transmembrane transporter activity", "Oligosaccharide binding", "Oligosaccharyl transferase activity", "Omega peptidase activity", "Opsonin binding", "Organic acid binding", "Organic acid sodium symporter activity", "Organic acid transmembrane transporter activity", "Organic anion transmembrane transporter activity", "Organic cation transmembrane transporter activity", "Organic hydroxy compound transmembrane transporter activity", "Organophosphate ester transmembrane transporter activity", "Oxidative phosphorylation uncoupler activity", "Oxidative rna demethylase activity", "Oxidized dna binding", "Oxidoreductase activity", "Oxidoreductase activity acting on a heme group of donors", "Oxidoreductase activity acting on a sulfur group of donors", "Oxidoreductase activity acting on a sulfur group of donors disulfide as acceptor", "Oxidoreductase activity acting on a sulfur group of donors nad p as acceptor", "Oxidoreductase activity acting on a sulfur group of donors oxygen as acceptor", "Oxidoreductase activity acting on ch oh group of donors", "Oxidoreductase activity acting on ch or ch2 groups", "Oxidoreductase activity acting on diphenols and related substances as donors", "Oxidoreductase activity acting on nad p h", "Oxidoreductase activity acting on nad p h heme protein as acceptor", "Oxidoreductase activity acting on nad p h oxygen as acceptor", "Oxidoreductase activity acting on nad p h quinone or similar compound as acceptor", "Oxidoreductase activity acting on other nitrogenous compounds as donors", "Oxidoreductase activity acting on other nitrogenous compounds as donors cytochrome as acceptor", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen nad p h as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced ascorbate as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced flavin or flavoprotein as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced pteridine as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water", "Oxidoreductase activity acting on peroxide as acceptor", "Oxidoreductase activity acting on single donors with incorporation of molecular oxygen", "Oxidoreductase activity acting on the aldehyde or oxo group of donors", "Oxidoreductase activity acting on the aldehyde or oxo group of donors disulfide as acceptor", "Oxidoreductase activity acting on the aldehyde or oxo group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors", "Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors oxygen as acceptor", "Oxidoreductase activity acting on the ch nh group of donors", "Oxidoreductase activity acting on the ch nh group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch nh2 group of donors", "Oxidoreductase activity acting on the ch nh2 group of donors oxygen as acceptor", "Oxidoreduction driven active transmembrane transporter activity", "Oxo acid lyase activity", "Oxygen binding", "Oxygen sensor activity", "Oxysterol binding", "P type calcium transporter activity", "P type potassium transmembrane transporter activity", "P type transmembrane transporter activity", "P53 binding", "Palmitoyl coa hydrolase activity", "Palmitoyl protein hydrolase activity", "Palmitoyltransferase activity", "Passive transmembrane transporter activity", "Patched binding", "Pattern recognition receptor activity", "Pdz domain binding", "Pentosyltransferase activity", "Peptidase activator activity", "Peptidase activator activity involved in apoptotic process", "Peptidase activity", "Peptidase regulator activity", "Peptide alpha n acetyltransferase activity", "Peptide antigen binding", "Peptide binding", "Peptide hormone binding", "Peptide hormone receptor binding", "Peptide lysine n acetyltransferase activity", "Peptide n acetyltransferase activity", "Peptide receptor activity", "Peptide transmembrane transporter activity", "Peptidoglycan binding", "Peptidyl proline 4 dioxygenase activity", "Peptidyl proline dioxygenase activity", "Peroxiredoxin activity", "Peroxisome proliferator activated receptor binding", "Peroxisome targeting sequence binding", "Phosphatase activator activity", "Phosphatase activity", "Phosphatase binding", "Phosphatase inhibitor activity", "Phosphatase regulator activity", "Phosphate ion binding", "Phosphatidic acid binding", "Phosphatidic acid transfer activity", "Phosphatidyl phospholipase b activity", "Phosphatidylcholine binding", "Phosphatidylcholine floppase activity", "Phosphatidylcholine transfer activity", "Phosphatidylcholine transporter activity", "Phosphatidylethanolamine binding", "Phosphatidylethanolamine flippase activity", "Phosphatidylglycerol binding", "Phosphatidylinositol 3 4 5 trisphosphate 3 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate 5 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate binding", "Phosphatidylinositol 3 4 bisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate 3 phosphatase activity", "Phosphatidylinositol 3 5 bisphosphate 5 phosphatase activity", "Phosphatidylinositol 3 5 bisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate phosphatase activity", "Phosphatidylinositol 3 kinase activity", "Phosphatidylinositol 3 kinase binding", "Phosphatidylinositol 3 kinase regulator activity", "Phosphatidylinositol 3 kinase regulatory subunit binding", "Phosphatidylinositol 3 phosphate binding", "Phosphatidylinositol 4 5 bisphosphate 3 kinase activity", "Phosphatidylinositol 4 5 bisphosphate 5 phosphatase activity", "Phosphatidylinositol 4 5 bisphosphate binding", "Phosphatidylinositol 4 5 bisphosphate phosphatase activity", "Phosphatidylinositol 4 phosphate binding", "Phosphatidylinositol 5 phosphate binding", "Phosphatidylinositol binding", "Phosphatidylinositol bisphosphate binding", "Phosphatidylinositol bisphosphate kinase activity", "Phosphatidylinositol bisphosphate phosphatase activity", "Phosphatidylinositol kinase activity", "Phosphatidylinositol monophosphate phosphatase activity", "Phosphatidylinositol phosphate 4 phosphatase activity", "Phosphatidylinositol phosphate 5 phosphatase activity", "Phosphatidylinositol phosphate binding", "Phosphatidylinositol phosphate kinase activity", "Phosphatidylinositol phosphate phosphatase activity", "Phosphatidylinositol transfer activity", "Phosphatidylinositol trisphosphate phosphatase activity", "Phosphatidylserine 1 acylhydrolase activity", "Phosphatidylserine binding", "Phosphatidylserine flippase activity", "Phosphatidylserine floppase activity", "Phosphodiesterase i activity", "Phosphofructokinase activity", "Phospholipase a1 activity", "Phospholipase a2 activity", "Phospholipase a2 inhibitor activity", "Phospholipase activity", "Phospholipase binding", "Phospholipase c activity", "Phospholipase d activity", "Phospholipase inhibitor activity", "Phospholipid binding", "Phospholipid scramblase activity", "Phospholipid transfer activity", "Phospholipid transporter activity", "Phosphoprotein binding", "Phosphoprotein phosphatase activity", "Phosphoric diester hydrolase activity", "Phosphoric ester hydrolase activity", "Phosphorus oxygen lyase activity", "Phosphorylation dependent protein binding", "Phosphoserine residue binding", "Phosphotransferase activity for other substituted phosphate groups", "Phosphotransferase activity nitrogenous group as acceptor", "Phosphotransferase activity phosphate group as acceptor", "Phosphotyrosine residue binding", "Platelet derived growth factor receptor binding", "Plus end directed microtubule motor activity", "Poly a binding", "Poly a specific ribonuclease activity", "Poly g binding", "Poly purine tract binding", "Poly pyrimidine tract binding", "Polynucleotide adenylyltransferase activity", "Polypeptide n acetylgalactosaminyltransferase activity", "Polysaccharide binding", "Polysome binding", "Polyubiquitin modification dependent protein binding", "Porin activity", "Potassium channel activity", "Potassium channel inhibitor activity", "Potassium channel regulator activity", "Potassium chloride symporter activity", "Potassium ion binding", "Potassium ion transmembrane transporter activity", "Pre mirna binding", "Pre mrna 3 splice site binding", "Pre mrna 5 splice site binding", "Pre mrna binding", "Pre mrna intronic binding", "Prenyltransferase activity", "Primary active transmembrane transporter activity", "Primary mirna binding", "Procollagen proline 4 dioxygenase activity", "Procollagen proline dioxygenase activity", "Profilin binding", "Proline rich region binding", "Promoter specific chromatin binding", "Protease binding", "Proteasome activating activity", "Proteasome binding", "Protein adp ribosylase activity", "Protein antigen binding", "Protein arginine n methyltransferase activity", "Protein arginine omega n asymmetric methyltransferase activity", "Protein arginine omega n monomethyltransferase activity", "Protein binding involved in heterotypic cell cell adhesion", "Protein c terminus binding", "Protein carboxyl o methyltransferase activity", "Protein carrier chaperone", "Protein containing complex binding", "Protein deacetylase activity", "Protein demethylase activity", "Protein dimerization activity", "Protein disaggregase activity", "Protein disulfide isomerase activity", "Protein disulfide reductase nad p activity", "Protein domain specific binding", "Protein folding chaperone", "Protein geranylgeranyltransferase activity", "Protein heterodimerization activity", "Protein homodimerization activity", "Protein kinase a binding", "Protein kinase a catalytic subunit binding", "Protein kinase a regulatory subunit binding", "Protein kinase activity", "Protein kinase b binding", "Protein kinase c activity", "Protein kinase c binding", "Protein lipid complex binding", "Protein macromolecule adaptor activity", "Protein membrane adaptor activity", "Protein methyltransferase activity", "Protein n terminus binding", "Protein phosphatase 1 binding", "Protein phosphatase 2a binding", "Protein phosphatase activator activity", "Protein phosphatase binding", "Protein phosphatase regulator activity", "Protein phosphorylated amino acid binding", "Protein prenyltransferase activity", "Protein self association", "Protein sequestering activity", "Protein serine kinase activity", "Protein serine threonine kinase activator activity", "Protein serine threonine kinase activity", "Protein serine threonine kinase inhibitor activity", "Protein serine threonine phosphatase activity", "Protein serine threonine phosphatase inhibitor activity", "Protein serine threonine tyrosine kinase activity", "Protein tag", "Protein transmembrane transporter activity", "Protein transporter activity", "Protein tyrosine kinase activator activity", "Protein tyrosine kinase activity", "Protein tyrosine kinase binding", "Protein tyrosine kinase inhibitor activity", "Protein tyrosine phosphatase activity", "Protein tyrosine serine threonine phosphatase activity", "Proteoglycan binding", "Proton channel activity", "Proton transmembrane transporter activity", "Proton transporting atp synthase activity rotational mechanism", "Pseudouridine synthase activity", "Purine nucleotide transmembrane transporter activity", "Pyrimidine nucleoside transmembrane transporter activity", "Pyrimidine nucleotide binding", "Pyrimidine nucleotide sugar transmembrane transporter activity", "Pyrophosphate hydrolysis driven proton transmembrane transporter activity", "Pyruvate dehydrogenase acetyl transferring kinase activity", "Pyruvate dehydrogenase activity", "Pyruvate transmembrane transporter activity", "Quaternary ammonium group binding", "Quaternary ammonium group transmembrane transporter activity", "Quinone binding", "R smad binding", "Racemase and epimerase activity", "Racemase and epimerase activity acting on carbohydrates and derivatives", "Rage receptor binding", "Rdna binding", "Receptor antagonist activity", "Receptor tyrosine kinase binding", "Regulatory rna binding", "Retinal binding", "Retinal dehydrogenase activity", "Retinoic acid binding", "Retinoic acid receptor binding", "Retinoic acid responsive element binding", "Retinoid x receptor binding", "Retinol binding", "Retromer complex binding", "Ribonuclease activity", "Ribonuclease p activity", "Ribonuclease p rna binding", "Ribonucleoprotein complex binding", "Ribonucleotide binding", "Ribose phosphate diphosphokinase activity", "Ribosomal large subunit binding", "Ribosomal protein s6 kinase activity", "Ribosomal small subunit binding", "Ribosome binding", "Rna 2 o methyltransferase activity", "Rna 7 methylguanosine cap binding", "Rna adenylyltransferase activity", "Rna binding", "Rna binding involved in posttranscriptional gene silencing", "Rna cap binding", "Rna directed dna polymerase activity", "Rna dna hybrid ribonuclease activity", "Rna methyltransferase activity", "Rna polymerase activity", "Rna polymerase binding", "Rna polymerase core enzyme binding", "Rna polymerase i general transcription initiation factor activity", "Rna polymerase i transcription regulatory region sequence specific dna binding", "Rna polymerase ii activity", "Rna polymerase ii c terminal domain binding", "Rna polymerase ii c terminal domain phosphoserine binding", "Rna polymerase ii core promoter sequence specific dna binding", "Rna polymerase ii ctd heptapeptide repeat kinase activity", "Rna polymerase ii general transcription initiation factor activity", "Rna polymerase ii general transcription initiation factor binding", "Rna polymerase ii specific dna binding transcription factor binding", "Rna polymerase iii transcription regulatory region sequence specific dna binding", "Rna stem loop binding", "Rna strand annealing activity", "Roundabout binding", "Rrna adenine methyltransferase activity", "Rrna binding", "Rrna cytosine methyltransferase activity", "S acyltransferase activity", "S adenosyl l methionine binding", "S adenosylmethionine dependent methyltransferase activity", "S methyltransferase activity", "S100 protein binding", "Scaffold protein binding", "Scavenger receptor activity", "Secondary active transmembrane transporter activity", "Semaphorin receptor activity", "Sequence specific dna binding", "Sequence specific mrna binding", "Sequence specific single stranded dna binding", "Serine hydrolase activity", "Serine transmembrane transporter activity", "Serine type carboxypeptidase activity", "Serine type endopeptidase inhibitor activity", "Serine type exopeptidase activity", "Sh2 domain binding", "Sh3 domain binding", "Signal recognition particle binding", "Signal sequence binding", "Signaling adaptor activity", "Signaling receptor binding", "Signaling receptor complex adaptor activity", "Signaling receptor inhibitor activity", "Signaling receptor regulator activity", "Single stranded dna 3 5 exodeoxyribonuclease activity", "Single stranded dna binding", "Single stranded dna endodeoxyribonuclease activity", "Single stranded dna exodeoxyribonuclease activity", "Single stranded dna helicase activity", "Single stranded rna binding", "Single stranded telomeric dna binding", "Sirna binding", "Smad binding", "Small molecule sensor activity", "Small protein activating enzyme binding", "Small ribosomal subunit rrna binding", "Snap receptor activity", "Snare binding", "Snorna binding", "Snrna binding", "Snrnp binding", "Sodium channel inhibitor activity", "Sodium channel regulator activity", "Sodium chloride symporter activity", "Sodium ion binding", "Sodium ion transmembrane transporter activity", "Solute anion antiporter activity", "Solute bicarbonate symporter activity", "Solute cation antiporter activity", "Solute cation symporter activity", "Solute proton antiporter activity", "Solute proton symporter activity", "Solute sodium symporter activity", "Spectrin binding", "Sphingolipid binding", "Sphingolipid transfer activity", "Sphingolipid transporter activity", "Sphingomyelin phosphodiesterase activity", "Sphingosine n acyltransferase activity", "Steroid binding", "Steroid dehydrogenase activity", "Steroid dehydrogenase activity acting on the ch oh group of donors nad or nadp as acceptor", "Steroid hormone binding", "Steroid hormone receptor activity", "Sterol binding", "Sterol esterase activity", "Sterol transfer activity", "Sterol transporter activity", "Structural constituent of cytoskeleton", "Structural constituent of eye lens", "Structural constituent of muscle", "Structural constituent of nuclear pore", "Structural constituent of postsynapse", "Structural constituent of postsynaptic actin cytoskeleton", "Structural constituent of presynaptic active zone", "Structural constituent of ribosome", "Structural constituent of synapse", "Structural molecule activity", "Structural molecule activity conferring elasticity", "Succinate transmembrane transporter activity", "Sulfate binding", "Sulfate transmembrane transporter activity", "Sulfatide binding", "Sulfotransferase activity", "Sulfur compound binding", "Sulfur compound transmembrane transporter activity", "Sulfuric ester hydrolase activity", "Sulfurtransferase activity", "Sumo binding", "Sumo ligase activity", "Sumo specific protease activity", "Sumo transferase activity", "Supercoiled dna binding", "Superoxide dismutase activity", "Superoxide generating nadph oxidase activator activity", "Symporter activity", "Syndecan binding", "Syntaxin 1 binding", "Syntaxin binding", "T cell receptor binding", "Tap binding", "Tap1 binding", "Tat protein binding", "Tau protein binding", "Tau protein kinase activity", "Tbp class protein binding", "Telomerase activity", "Telomerase inhibitor activity", "Telomerase rna binding", "Telomeric dna binding", "Testosterone dehydrogenase nad p activity", "Testosterone dehydrogenase nadplus activity", "Tetrapyrrole binding", "Tfiib class transcription factor binding", "Tfiid class transcription factor complex binding", "Thiamine pyrophosphate binding", "Thioesterase binding", "Thiol oxidase activity", "Thiolester hydrolase activity", "Thioredoxin disulfide reductase activity", "Threonine type endopeptidase activity", "Threonine type peptidase activity", "Thyroid hormone receptor binding", "Titin binding", "Toxic substance binding", "Tpr domain binding", "Transcription coactivator activity", "Transcription coactivator binding", "Transcription coregulator activity", "Transcription coregulator binding", "Transcription corepressor activity", "Transcription corepressor binding", "Transcription elongation regulator activity", "Transcription factor binding", "Transcription regulator activity", "Transcription regulator inhibitor activity", "Transferase activity transferring alkyl or aryl other than methyl groups", "Transferase activity transferring nitrogenous groups", "Transferase activity transferring one carbon groups", "Transferase activity transferring phosphorus containing groups", "Transferase activity transferring sulphur containing groups", "Transferrin receptor binding", "Transforming growth factor beta binding", "Transforming growth factor beta receptor binding", "Transition metal ion binding", "Transition metal ion transmembrane transporter activity", "Transketolase or transaldolase activity", "Translation activator activity", "Translation elongation factor activity", "Translation factor activity rna binding", "Translation initiation factor activity", "Translation initiation factor binding", "Translation regulator activity", "Translation regulator activity nucleic acid binding", "Translation repressor activity", "Translation repressor activity mrna regulatory element binding", "Translation termination factor activity", "Transmembrane receptor protein kinase activity", "Transmembrane receptor protein phosphatase activity", "Transmembrane receptor protein tyrosine kinase activity", "Transmembrane receptor protein tyrosine kinase adaptor activity", "Transmembrane transporter binding", "Transporter activity", "Triglyceride lipase activity", "Tripeptide transmembrane transporter activity", "Trna binding", "Trna cytosine methyltransferase activity", "Trna guanine methyltransferase activity", "Trna methyltransferase activity", "Trna specific adenosine deaminase activity", "Trna specific ribonuclease activity", "Tropomyosin binding", "Tubulin binding", "Tumor necrosis factor activated receptor activity", "Tumor necrosis factor receptor binding", "Tumor necrosis factor receptor superfamily binding", "Type i transforming growth factor beta receptor binding", "U1 snrna binding", "U2 snrna binding", "U3 snorna binding", "U4 snrna binding", "U6 snrna binding", "Ubiquinol cytochrome c reductase activity", "Ubiquinone binding", "Ubiquitin binding", "Ubiquitin conjugating enzyme binding", "Ubiquitin ligase substrate adaptor activity", "Ubiquitin like modifier activating enzyme activity", "Ubiquitin like protein binding", "Ubiquitin like protein conjugating enzyme activity", "Ubiquitin like protein conjugating enzyme binding", "Ubiquitin like protein ligase activity", "Ubiquitin like protein ligase binding", "Ubiquitin like protein specific isopeptidase activity", "Ubiquitin like protein specific protease activity", "Ubiquitin like protein transferase activity", "Ubiquitin protein transferase activator activity", "Ubiquitin protein transferase inhibitor activity", "Ubiquitin protein transferase regulator activity", "Ubiquitin specific protease binding", "Ubiquitin ubiquitin ligase activity", "Ubiquitination like modification dependent protein binding", "Udp galactose beta n acetylglucosamine beta 1 3 galactosyltransferase activity", "Udp glucosyltransferase activity", "Udp glycosyltransferase activity", "Udp xylosyltransferase activity", "Unfolded protein binding", "Unmethylated cpg binding", "Uridine transmembrane transporter activity", "Uridylyltransferase activity", "Vascular endothelial growth factor activated receptor activity", "Vascular endothelial growth factor binding", "Vascular endothelial growth factor receptor 2 binding", "Vascular endothelial growth factor receptor binding", "Very long chain fatty acid coa ligase activity", "Vinculin binding", "Virion binding", "Vitamin b6 binding", "Vitamin binding", "Vitamin d binding", "Vitamin d receptor binding", "Vitamin transmembrane transporter activity", "Voltage gated anion channel activity", "Voltage gated calcium channel activity", "Voltage gated calcium channel activity involved in regulation of cytosolic calcium levels", "Voltage gated cation channel activity", "Voltage gated channel activity", "Voltage gated chloride channel activity", "Volume sensitive anion channel activity", "Water channel activity", "Water transmembrane transporter activity", "Wd40 repeat domain binding", "Wide pore channel activity", "Wnt protein binding", "Ww domain binding", "Xenobiotic transmembrane transporter activity", "Y form dna binding", "Zinc ion binding"], "available_proteins": ["AACS", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABHD10", "ABHD12", "ABHD6", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ADA", "ADAM17", "ADAM9", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG2", "ALG5", "ALKBH5", "ALYREF", "AMOT", "AMPD2", "ANAPC1", "ANAPC2", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "APBB1", "APC", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOBEC3C", "APOL2", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARIH1", "ARL1", "ARL10", "ARL2", "ARL3", "ARL6IP1", "ARL8B", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARVCF", "ASAH1", "ASCC2", "ASCC3", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG4B", "ATG9A", "ATIC", "ATL2", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPIF1", "ATRX", "ATXN2L", "AUP1", "AURKB", "B4GAT1", "BABAM2", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAP18", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP31", "BCAS3", "BCAT2", "BCCIP", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BDH2", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD2", "BRD3", "BRD4", "BRD7", "BRD8", "BRIX1", "BSG", "BTF3", "BTRC", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C1D", "C1QBP", "C1orf123", "C1orf35", "C2CD2L", "C2CD5", "CAB39", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAMLG", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN7", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CAST", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC22", "CCDC47", "CCDC6", "CCDC86", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC20", "CDC23", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC6", "CDC73", "CDCA5", "CDH2", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDKN2AIP", "CDR2L", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPV", "CEP135", "CEP250", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CGN", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP4B", "CHMP5", "CHMP6", "CHORDC1", "CHP1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CIZ1", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLSTN3", "CLTA", "CLTC", "CLU", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNOT7", "CNOT9", "CNP", "COIL", "COLEC12", "COLGALT1", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS4", "COPS5", "COPS6", "COQ8A", "COQ8B", "COQ9", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7A2L", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CREB1", "CREG1", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CRYZL1", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTH", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CUTA", "CWC15", "CWC22", "CWF19L1", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCD", "DCP1A", "DCP2", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DECR1", "DEK", "DENND4C", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS4", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB4", "DNAJC1", "DNAJC10", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPM1", "DPP3", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS3L", "DUSP12", "DUSP3", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC3", "EDF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EEFSEC", "EFHD1", "EFL1", "EFTUD2", "EGFR", "EHD1", "EHD4", "EHHADH", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENPP1", "ENSA", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPDR1", "EPHA7", "EPHX1", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EYA4", "EZH2", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAHD1", "FAHD2A", "FAM120A", "FAM129B", "FAM208A", "FAM213A", "FAM3C", "FAM49B", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD5", "FAU", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FMR1", "FN3KRP", "FNBP1L", "FNDC3A", "FOXK1", "FOXK2", "FOXRED1", "FSCN1", "FSTL1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCN1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GGH", "GGPS1", "GHDC", "GIGYF2", "GLA", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA13", "GNAI2", "GNAI3", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA4", "GOLGA5", "GOLGB1", "GOLPH3", "GOLPH3L", "GOPC", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPR107", "GPR89B", "GPRASP2", "GPS1", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C4", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS4", "HAUS6", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDGFL2", "HDHD2", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIRA", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN3", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK2", "HOXD13", "HP1BP3", "HPRT1", "HPS6", "HPSE", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPAD1", "IMPDH2", "INA", "INCENP", "INF2", "INTS11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRS4", "ISCU", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITM2B", "ITM2C", "ITPA", "ITPRIP", "IVD", "JMJD6", "JUP", "KARS", "KAT7", "KCTD12", "KCTD5", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0368", "KIAA0391", "KIF11", "KIF14", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KMT2A", "KNOP1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAMTOR3", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LPGAT1", "LRBA", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRRC40", "LRRC47", "LRRC59", "LRRC8C", "LRRFIP2", "LRSAM1", "LRWD1", "LSG1", "LSM14B", "LSM2", "LSM3", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LZIC", "LZTFL1", "MACF1", "MAD2L1", "MAGED1", "MAGT1", "MAK16", "MAN1A1", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K4", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARCKSL1", "MARK2", "MARK3", "MARS", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED21", "MED23", "MED24", "MED25", "MED4", "MEN1", "MEPCE", "MESD", "METAP1", "METTL13", "METTL15", "MFAP1", "MFF", "MFN1", "MFSD10", "MFSD3", "MFSD5", "MGEA5", "MGME1", "MGST1", "MGST2", "MGST3", "MIA3", "MICU1", "MICU2", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MKRN2", "MLEC", "MMAB", "MMS19", "MOGS", "MORC2", "MORF4L1", "MOV10", "MPC2", "MPDZ", "MPG", "MPHOSPH10", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP5", "MPP7", "MPRIP", "MPST", "MRC2", "MRE11", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL39", "MRPL40", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL49", "MRPL55", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTDH", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTM1", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTR", "MUT", "MYBBP1A", "MYCBP", "MYCBP2", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO6", "NAA10", "NAA15", "NAA40", "NAA50", "NACC1", "NADK2", "NAE1", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCBP1", "NCBP3", "NCK1", "NCK2", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "NDC1", "NDUFA10", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFC2", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NEU1", "NF2", "NFRKB", "NFS1", "NFU1", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NISCH", "NKRF", "NKTR", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NME3", "NME7", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NRBP1", "NRDC", "NRP1", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDT1", "NUDT12", "NUDT16L1", "NUDT21", "NUDT5", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP35", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCLN", "OCRL", "OGDH", "OGFOD3", "OGT", "OLA1", "OPA1", "ORC2", "ORC3", "ORC5", "OS9", "OSBP", "OSBPL11", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD7B", "OXA1L", "OXSR1", "P3H1", "P3H3", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PAOX", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PAWR", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH19", "PCID2", "PCK2", "PCM1", "PCMT1", "PCNA", "PCYOX1", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE4DIP", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDP1", "PDPR", "PDSS2", "PDXK", "PEBP1", "PECR", "PEF1", "PELP1", "PEPD", "PES1", "PEX14", "PEX16", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHRF1", "PI4K2A", "PI4KA", "PI4KB", "PIBF1", "PICALM", "PIGK", "PIGL", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PIR", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PKP2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLS1", "PLS3", "PLXNB2", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POFUT1", "POFUT2", "POLA1", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3F", "POLRMT", "POMGNT2", "PON2", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP1R9B", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA3", "PSMA4", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PWWP2A", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "PYM1", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABEP1", "RABGAP1", "RABGGTA", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBFOX2", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "RECQL5", "REEP3", "REEP4", "REL", "REPS1", "RER1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RICTOR", "RIDA", "RILPL1", "RIOX1", "RIOX2", "RMDN1", "RMDN3", "RNASEH2A", "RNASET2", "RNF114", "RNF14", "RNF20", "RNF219", "RNF40", "RNH1", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS19BP1", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RTCA", "RTCB", "RTN4", "RTN4IP1", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "RXRB", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAP18", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SATB2", "SBDS", "SBNO1", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAMP1", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDCBP", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT8", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHC1", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIKE1", "SIN3A", "SIN3B", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC30A7", "SLC35A4", "SLC35B2", "SLC35F2", "SLC38A2", "SLC3A2", "SLC4A1AP", "SLC4A7", "SLC5A6", "SLC6A15", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG9", "SMN1*", "SMNDC1", "SMPD4", "SNAP23", "SNAP29", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG5", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC24", "SPCS2", "SPCS3", "SPEN", "SPNS1", "SPOUT1", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRBD1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAU1", "STAU2", "STIP1", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX3", "STX5", "STX6", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYNCRIP", "SYNE2", "TAB1", "TACO1", "TAF15", "TAF4", "TAF7", "TAGLN2", "TALDO1", "TAMM41", "TAOK3", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCF25", "TCOF1", "TCP1", "TDP2", "TDRKH", "TECR", "TELO2", "TENM3", "TERF2IP", "TES", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFG", "TFRC", "TGFBRAP1", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM13", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TIMM9", "TJP1", "TJP2", "TK1", "TKT", "TLN1", "TMCO1", "TMED1", "TMED10", "TMED9", "TMEM109", "TMEM165", "TMEM192", "TMEM201", "TMEM30A", "TMEM38B", "TMEM43", "TMEM59", "TMEM70", "TMF1", "TMLHE", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOM1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOPBP1", "TOR1A", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TOX4", "TP53", "TP53BP1", "TP53BP2", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRIT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPO", "TSPYL1", "TSR1", "TST", "TSTA3", "TTC1", "TTC21B", "TTC26", "TTC4", "TTC5", "TTF2", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWNK", "TXLNA", 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pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Disproportionate short limb short stature 10 22 3.0108317358797554 0.0026053318321075 6.587378640776699 19.902912621359224 1.344701363676014 0.2682000023842777 2.8599402401133336 3.1206003999939886 0.9439707190715964 0.2973700803613334 0.0095842407755732 0.0421554091664212 0.0275216398495969 0.0833669979064696 0.0004056006267912 +Disproportionate short stature 12 26 2.965755665786224 0.0030194026433678 8.58252427184466 24.70145631067961 1.4449047806081987 0.2464238748623315 3.3320283680556178 3.793287097673045 1.0910515137563812 0.2952991105687103 0.0046700771911843 0.0680396063598938 0.0105112684317993 0.0211615022147258 0.0003517763086107 +Rhizomelia 6 13 2.913544999244385 0.0035735033007311 4.276699029126213 11.868932038834952 1.3783619481702345 0.228956695884812 2.09278482575067 1.6655579622091714 0.936017394236602 0.2616202806826952 0.018616123513834 0.0204708743585679 0.0096938597365547 0.100752004546059 0.0064270949220598 +Variable expressivity 27 80 2.843672580996691 0.0044596850110016 16.655339805825243 76.72572815533981 0.9137081973948464 0.4866305980303022 6.903822328870412 7.203694993346709 1.0588933116250316 0.3878161256963057 0.0146730369736622 0.0796260892263804 0.1434578911288594 0.0708155641306423 0.0013856379631531 +Phenotypic variability 32 105 2.677738231275125 0.0074121121013301 22.339805825242717 99.4368932038835 0.8464119152872666 0.5170730885331468 8.500203764614474 8.607030207254683 1.0360918895927824 0.3938137781932724 0.020119128997006 0.0429933331741239 0.12647485688785 0.1360834878205354 0.0020706197995487 +Ragged red muscle fibers 5 20 2.6735104531641163 0.0075061936823153 5.233009708737864 17.730582524271846 1.450228655394427 0.2143723456093393 2.356374883616516 2.3878203593303375 1.2019998086948689 0.268108115907532 0.001270666906883 0.0008441205885139 0.000509979222831 0.0023954143814766 0.010788368915323 +Bulbar signs 6 12 2.545875111972965 0.0109004178626441 4.888349514563107 12.016990291262136 1.527818207801298 0.1656113111527082 2.218011046873564 1.4803576942139227 1.2783367300196684 0.2344360472575242 0.006884119919632 0.0102371045657047 0.0034893000144238 0.0071928662194731 0.0182596420242621 +Abnormal muscle fiber morphology 22 73 2.4723167123262657 0.013424053052502 17.78640776699029 68.04126213592232 1.263675841483234 0.3649599499596623 6.500784844979595 6.6307423444197315 1.1691802531751734 0.3853191125649093 0.0008001606779819 0.0419630621111095 0.0044993200044086 0.0001488438731698 3.1583163599169e-06 +Abnormal pleura morphology 5 23 2.4616582521749724 0.0138296371884412 5.830097087378641 21.546116504854368 0.7290082089123371 0.4905463652617658 2.6668163977506785 3.2642978200941286 0.7757959562897808 0.3157493889189873 0.0749303089074102 0.3208381238265493 0.1793408912067547 0.3083918196183406 0.1944132869758354 +Central scotoma 7 11 2.4549158419808625 0.014091757429175 3.657766990291262 9.152912621359222 1.2790732929494344 0.2261272578521709 2.0233738200365714 2.077016218281829 1.2675536526802949 0.279373459017325 0.0428688471843709 0.0073558029266518 0.0274603336438859 0.0270423729706739 0.000237302398801 +Segmental peripheral demyelination remyelination 3 5 2.4537118573441226 0.0141390225481026 1.6601941747572817 4.737864077669903 1.1231406516527276 0.2457358043386077 1.1021021225411718 1.375663406058269 1.1869683790120098 0.2709829643602553 9.876874344201966e-06 2.2261381171916983e-05 0.0001778916397324 0.0001450038876457 0.0020183200628615 +Metaphyseal dysplasia 2 12 2.4406712577313185 0.0146599931182858 2.6189320388349513 10.4247572815534 0.485435274486908 0.5421266798600373 2.0908795996507425 1.593880496830027 0.7911796361418049 0.3013045749035116 0.2565011198123136 0.1093006244161378 0.2070995190727305 0.0197332243190265 0.1093101132411038 +Inability to walk 17 88 2.4126309434955497 0.0158378472819837 16.66504854368932 84.69902912621359 0.4056115860733718 0.6149200897254583 7.231232270040466 7.352874018977716 0.8216232864046632 0.3415658846811537 0.0108850281179211 0.0693533768434635 0.1230477794043109 0.0228391496827617 0.0080105031619167 +Abnormal epiphyseal ossification 11 20 2.4078125110321147 0.0160484203799273 6.451456310679611 16.274271844660195 1.1227269321938518 0.3276999393402902 3.140724178369711 2.4155680760400804 1.043634905787503 0.3148370578580727 0.4195293342885178 0.1913705796369965 0.3467918934582977 0.0216647555097342 0.0011303287485076 +Spondyloepimetaphyseal dysplasia 2 6 2.380517173834603 0.0172883551538192 2.046116504854369 6.87378640776699 0.6291617473675466 0.4421176103682042 1.294240214952168 1.435876050377699 0.927363068507802 0.3097679752285407 0.1376604381754921 0.0561990347849709 0.1094892401774078 0.0026581093268102 0.0182159139614431 +Coxa vara 6 16 2.3635923997690957 0.018098712776037 4.310679611650485 13.54126213592233 0.853738655548226 0.4218003203060939 1.9720332330132235 1.9928869528934432 0.8140335419312188 0.3116542205645756 0.0897530613876027 0.1795501084992132 0.0588586045542952 0.0029974307870657 0.0033280295566654 +Decreased number of peripheral myelinated nerve fibers 7 16 2.358925871897591 0.0183279164520977 4.269417475728155 15.449029126213592 0.5470641849851599 0.5309325631616826 2.362271543479177 2.3749959691588103 0.7924715482597077 0.3124068087690249 0.0682444880843565 0.1553991536419083 0.2872333566147377 0.0525727870350727 0.0888289826938022 +Generalized joint laxity 2 14 2.3518002035007424 0.018682807047418 2.7815533980582523 11.79368932038835 0.6564693612664338 0.4622151090919249 1.854108404410052 1.1421572930726116 0.9213406108825204 0.3139838952541599 0.0047113831635554 1.0 0.0023694947377154 0.029757296929711 0.1539585868211262 +Aplasia hypoplasia involving bones of the lower limbs 31 98 2.3517302975355867 0.0186863182540055 19.410194174757283 88.28155339805825 0.2455434370550195 0.7366360730888745 6.913416881109145 11.322215876065782 0.6022756981459902 0.2969807113615431 0.1457070740339841 0.4082525861146306 0.1466932442065239 0.0966528290085427 0.0740685427924758 +Pleural effusion 4 12 2.3479954213061207 0.0188747533266775 2.9805825242718447 10.919902912621358 0.7132265525387661 0.4494075026638777 1.784401575053615 1.8370227047476868 0.7991368875087426 0.2902305603934778 0.1011618969826921 0.1913705796369965 0.3467918934582977 0.2903927816552063 0.0614446561434308 +Peripheral demyelination 9 16 2.335222527467372 0.0195317988878829 4.524271844660194 16.973300970873787 0.9472740181618832 0.3208012027704231 2.3341893675900383 2.269845761985369 1.1784704386991718 0.3026863353342601 0.0011511510513964 0.0007818203448131 0.005693097574516 0.013184387389335 0.0095095891823194 +Postural tremor 4 17 2.331722654362052 0.0197152862402998 5.194174757281553 17.851941747572816 1.214872214945056 0.2487017685351703 2.341305968762478 2.2981463861426747 1.2391489410765593 0.2821199379659175 0.0127748373260935 0.0009094910101507 0.0065760397653667 0.0157211013123339 0.0435237537141962 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0.0231416904465933 1.3106796116504855 5.007281553398058 0.8088648966265131 0.3483026313211161 1.0430456357811864 1.087191709833904 1.1553193033520868 0.3106693264231038 0.0222503661100739 0.0036723611473879 0.014058804472369 0.0768284795296569 0.236286730772413 +Abnormal speech prosody 1 8 2.266662481330542 0.0234108520304245 1.7184466019417477 7.531553398058253 0.8238611105871386 0.3292070194756458 1.3593793253030109 1.1305443806694235 1.0768574157850217 0.2870822069632543 0.0179800497482818 0.0029386578360865 0.0113213926532688 0.0630532374058985 0.1998160014011807 +Mitochondrial respiratory chain defects 2 6 2.255709209968533 0.0240888484034289 1.8033980582524272 5.177184466019417 1.0048180638921334 0.285673153216041 1.1353491002390874 1.0681459460620504 1.0953831291184488 0.2879410254685434 0.0159916695081137 0.0026008925831016 0.0100519320580488 0.0062969264366488 0.0401461367370898 +Hemiparesis 6 17 2.2333662000480894 0.0255248052182628 4.492718446601942 16.453883495145632 0.5632847994166561 0.5250125610456521 2.3039529956499933 2.7457486053720115 0.80325121159606 0.3108877318797908 0.1673900106944748 0.0335548880884004 0.1132051672598368 0.1789420187780838 0.0259419504317075 +Limb muscle weakness 32 85 2.2326452252563107 0.0255723492207862 17.839805825242717 80.70388349514563 0.4827776345811875 0.6059822076523635 6.801525240221059 8.816890479868707 0.7698087425405967 0.3425134280672268 0.0129952099073698 0.0752674265862488 0.0473694372220574 0.0628453426840141 0.0053345621069596 +Increased connective tissue 2 8 2.2284284098292164 0.0258519603544244 2.5145631067961167 7.502427184466019 0.8156544766596637 0.4080201432400869 1.4337409663669696 0.673704389121222 0.9233752682577614 0.3237190879475042 0.0222503661100739 0.0875404472016038 0.1677870330809631 0.0103266247469619 0.0624183143373935 +Aplasia hypoplasia involving the carpal bones 0 6 2.227512948315945 0.0259130114066923 1.8470873786407769 5.08252427184466 -0.0288033780484508 0.6010266986729026 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0.3080162794814239 0.3181646490698998 0.1389130578490434 0.2590666885683055 0.534424974066877 0.0160305095638712 +Cogwheel rigidity 0 6 2.1582072009231754 0.0309117257954627 1.691747572815534 5.41747572815534 0.5245835815764137 0.3763230502268936 1.2788913032023987 1.4212279105346624 1.148580263275354 0.3055796210169491 0.1792312731033967 0.0742352733278267 0.1432798584585485 0.3258327648280404 0.5507460232908605 +Atrophy degeneration involving the caudate nucleus 2 6 2.146443008469342 0.0318376511075608 1.2888349514563109 4.283980582524272 0.3751529128205025 0.4147621281846377 1.0481475114547032 1.0836094304135666 1.1513114797047737 0.3142236199023666 0.1376604381754921 0.0561990347849709 0.1094892401774078 0.2559514735144251 0.0182159139614431 +Sensorimotor neuropathy 9 33 2.14498305334054 0.0319542019673524 8.980582524271844 31.118932038834952 1.3016328701661894 0.3009249972125085 3.646997920951252 3.5836645053134393 1.2437208862143418 0.3260038325488978 0.0016371821499902 0.0045553852335938 0.029653655190088 0.0069724305915864 0.0019686501934564 +Deformed sella turcica 0 5 2.121401563703311 0.0338880237902476 1.449029126213592 4.361650485436893 0.6519584745232953 0.4108786670869809 1.0702617541763486 1.191712968868623 0.98030484078304 0.3007326817007539 0.1376604381754921 0.0561990347849709 0.1094892401774078 0.2559514735144251 0.4511907478135378 +Low frustration tolerance 1 10 2.115946193036012 0.0343493840988067 2.2402912621359223 8.861650485436893 0.6170800437496735 0.4474642212406593 1.8402268519458895 1.0394103977385205 0.9109780988264436 0.3087684537640934 0.0159916695081137 0.0742352733278267 0.0100519320580488 0.0565188023636715 0.1818418904091173 +Lower limb pain 0 5 2.108844966804867 0.0349579657791041 1.5825242718446602 4.990291262135922 0.5428874178676697 0.3877045147354496 1.3258027196203157 1.119076818129616 1.1147585770582464 0.3126977330206063 0.1992649039447594 0.083126337411673 0.1596960736798767 0.3582816735878424 0.5935435236326052 +Bilateral sensorineural hearing impairment 10 25 2.106915995707181 0.0351248618267283 6.381067961165049 24.424757281553397 0.7447297270654177 0.4543730451773109 2.694462286764978 2.8252792093863337 0.8997615483176746 0.3241521581359238 0.1416773753306243 0.2295798469686227 0.4072036678679048 0.1435696883620607 0.0043344107943581 +Mitochondrial inheritance 2 5 2.085814506506498 0.0369954288595635 1.577669902912621 4.247572815533981 0.9928856357718184 0.2727497270810077 1.119676794457053 1.2095369137272214 1.2442723588935711 0.2811589341958167 0.0141047644752725 0.0022827689145391 0.0088504827764808 0.050241067872642 0.0338099842169397 +Achilles tendon contracture 7 12 2.084274053672173 0.0371352460593781 4.004854368932039 11.279126213592232 0.5734466657319717 0.5136155316960331 2.137273403229174 1.1955626751800683 0.8553039294976645 0.3252433518045028 0.3096765085512921 1.0 1.0 0.1648346062433529 0.0139902560164694 +Aplasia hypoplasia of the capital femoral epiphysis 1 7 2.083464511726911 0.0372089032472371 1.4344660194174756 5.019417475728155 0.4404435176817264 0.4586115848866851 1.1692153440192188 1.5902041300501577 0.9972055316061226 0.3108875242391429 0.0090809806489247 0.0561990347849709 0.1094892401774078 0.0331187861076589 0.0182159139614431 +Absent epiphyses 1 8 2.070355817883877 0.0384190360617715 1.6601941747572817 6.019417475728155 0.3808059139538731 0.4787450056067535 1.354986461855146 1.5902041300501577 0.9446543923619232 0.3021365086610809 0.0106465592757744 0.0607401038440192 0.1180585699575878 0.0385233102424958 0.0228394808772788 +Abnormal circulating citrulline concentration 1 5 2.069093711178694 0.038537293763579 1.519417475728155 4.283980582524272 0.9322911204120568 0.2795135602214257 1.0297099461920487 1.0355035731992424 1.235992875942202 0.2843671782204088 0.0090809806489247 0.0014481500629001 0.0056684159955205 0.0331187861076589 0.113339965404402 +Papule 6 18 2.0645213849266506 0.0389683084471055 4.70873786407767 18.25 0.6926476657665993 0.4861454686888452 2.1905847424395684 2.177360341847997 0.753924239039255 0.307804830985797 0.4807987606017377 0.225839943305071 0.4014202890149608 0.0090716565927419 0.0138300064936424 +Progressive external ophthalmoplegia 2 10 2.0562701458740347 0.0397564842416857 3.378640776699029 10.228155339805824 0.6986896615619974 0.3934319655103426 1.8174798771838792 2.269764004486748 0.9524665755192452 0.2940766219203315 0.2835780603485869 0.1221118561195742 0.2297987482657219 0.4860897569734319 0.1423023069394473 +Abnormal auditory evoked potentials 5 10 2.0416158601613312 0.04118965081277 2.837378640776699 8.45388349514563 0.8113355275163785 0.2966376606156203 1.5470802196866602 1.3128600166506037 1.1722229382642326 0.2813987538538041 0.2188133634327789 1.0 1.0 0.3891747515056749 0.0022722304352638 +Personality changes 8 18 2.0320808254805924 0.0421454741906202 4.235436893203883 16.20873786407767 0.716641708966708 0.4361664780008399 2.2513009299259603 2.2727002372019856 0.9467269936740988 0.3182188186141179 0.3747515154510799 0.1675604235637086 0.3076603852203092 0.6083683872182535 0.0095095891823194 +Horizontal nystagmus 7 24 2.0267811380317906 0.0426848002748427 6.274271844660194 23.053398058252423 1.1086320165192889 0.2915732095622053 2.6115907074401723 2.1860242554539786 1.3408731048130669 0.3129960018850027 0.1416773753306243 0.2295798469686227 0.0949012099695084 0.1435696883620607 0.0465202107555725 +Abnormal greater sciatic notch morphology 1 6 2.014028515772581 0.0440065397022901 1.5266990291262137 4.774271844660194 0.5311073615188446 0.5175259822444115 1.160333805628576 1.2676015896874502 0.8322004072094659 0.3157464750199098 0.1893094745604938 0.0786913117950012 0.1515272625734178 0.0630532374058985 0.1998160014011807 +Blurred vision 1 5 2.0103696978611474 0.0443920751435094 1.4684466019417477 4.449029126213592 0.7772225957067546 0.3401357669580369 0.986055451759567 0.9450042528934012 1.0938682095756602 0.2939628040587096 0.0222503661100739 0.0036723611473879 0.014058804472369 0.0768284795296569 0.236286730772413 +Capillary hemangioma 3 8 1.9836891636806924 0.0472905023295131 2.533980582524272 7.133495145631068 1.1471796350867234 0.2683759543048971 1.4112277515033682 1.3471092449900268 0.9767941621718578 0.2786452679412407 0.0615154966441759 1.0 0.2732850813359189 0.0453869127531283 0.0747991773170861 +Proximal amyotrophy 5 15 1.9671630794531425 0.0491644129494888 4.718446601941747 13.856796116504857 0.6037658559324836 0.4972994712742096 2.2062025350790946 1.7602342703705265 0.8206757208003167 0.3130721595344946 0.0428688471843709 1.0 1.0 0.0038594647505617 0.0016034677277021 +Polyneuropathy 5 17 1.967042122961865 0.0491783547733315 5.689320388349515 18.633495145631063 1.1475655107151586 0.297256939859202 2.871111980426299 2.8359934163787166 1.1251440285742276 0.3008764483611514 0.1333117556578677 0.0257535715284909 0.0890100643743446 0.1323508586296182 0.0397377338982377 +Onion bulb formation 5 7 1.963111153140482 0.0496332598804254 2.349514563106796 7.970873786407767 0.5150646293879767 0.4549381092129949 1.538873234646762 1.9506350008138953 0.9326070078767312 0.299017222140306 0.0293502839846989 0.1006582454154426 0.191600110602388 0.0990342687178565 0.0892170338783466 diff --git a/msigdb_hp/metrics.json b/msigdb_hp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..1d27d2de669f87d129ceceb658eeff59dd52c8ad --- /dev/null +++ b/msigdb_hp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3381, + "annotations_size": 4658, + "title": "Average number of proteins per term", + "value": 24.77114641477029 +} \ No newline at end of file diff --git a/msigdb_hp/paths.json b/msigdb_hp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..3a98a46d13d23f17967736ca9c8d4971c19d44d5 --- /dev/null +++ b/msigdb_hp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_hp/fragment/C317/C317_val_log2fc"} \ No newline at end of file diff --git a/msigdb_hp/result.tsv b/msigdb_hp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..18cb1024edacdbec6a18d6ae55fdafe123afec3d --- /dev/null +++ b/msigdb_hp/result.tsv @@ -0,0 +1,1537 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Disproportionate short limb short stature 0.6834754328942927 3.0108317358797554 0.0026053318321075 0.9999947194054616 0.962706331199288 22 Q7RTS9,Q15125,Q32P28,O00116,Q03164,Q15392,O75718,Q7LGA3,Q8NCM8,Q14739 10 +Disproportionate short stature 0.6745152596755274 2.9657556657862236 0.0030194026433678 0.99999923672951 0.962706331199288 26 Q7RTS9,Q15125,Q32P28,O00116,Q03164,Q15392,O75718,Q7LGA3,Q8NCM8,Q14739,Q96HY6,Q9UHX1 12 +Rhizomelia 0.8006609156029884 2.913544999244385 0.0035735033007311 0.9999999427129118 0.962706331199288 13 Q7RTS9,Q15125,O00116,O75718,Q15392,Q03164 6 +Variable expressivity 0.4907654120953181 2.843672580996691 0.0044596850110016 0.9999999990919048 0.962706331199288 80 Q8NI60,Q13813,Q70HW3,Q9Y5P6,Q9Y4W6,P03886,O95470,Q15125,O00429,Q9NR77,Q8TD16,Q53H12,O43707,Q9Y3Z3,Q00577,P00403,P00374,Q13868,Q8WVQ1,P07196,P06753,P07602,Q9H9S5,Q9UEY8,Q15058,Q6P4A7,Q9H3H1 27 +Phenotypic variability 0.4367746404443608 2.677738231275125 0.0074121121013301 0.9999999999999992 0.962706331199288 105 Q8NI60,Q13813,Q70HW3,Q9Y5P6,Q9UBB4,Q9Y4W6,P03886,O60313,O95470,P00846,Q15125,O00429,O60333,Q9NR77,Q8TD16,Q53H12,O43707,O14979,Q9Y3Z3,Q00577,P00403,P00374,Q13868,Q8WVQ1,P07196,P06753,P07602,Q9H9S5,Q9UEY8,Q15058,Q6P4A7,Q9H3H1 32 +Ragged red muscle fibers 0.6337680520569627 2.6735104531641163 0.0075061936823153 0.9999999999999994 0.962706331199288 20 P00846,Q9H2D1,Q70HW3,P03886,O95831 5 +Bulbar signs 0.7433764738721174 2.5458751119729652 0.0109004178626441 1.0 0.962706331199288 12 P00846,Q99720,P06753,P03886,P35637,O43681 6 +Abnormal muscle fiber morphology 0.4912378551438252 2.4723167123262657 0.013424053052502 1.0 0.962706331199288 73 Q8NI60,Q70HW3,Q9Y4W6,P03886,O60313,Q8WXH0,Q9BPX6,P00846,O14979,O43676,Q13501,Q9H2D1,P00403,P61978,O95831,P35609,Q99720,P07196,P06753,P35637,Q9H9S5,P50402 22 +Abnormal pleura morphology 0.6033001656640303 2.4616582521749724 0.0138296371884412 1.0 0.962706331199288 23 Q8NCH0,Q9UID3,Q9NZ08,Q14739,P49815 5 +Central scotoma 0.7527728271826266 2.4549158419808625 0.014091757429175 1.0 0.962706331199288 11 P00846,O60220,O00429,P03886,Q8WWV3,O60313,Q9H6K4 7 +Segmental peripheral demyelination remyelination 0.9265669357609048 2.4537118573441226 0.0141390225481026 1.0 0.962706331199288 5 P00846,Q9NR77,P03886 3 +Metaphyseal dysplasia 0.723516652320456 2.4406712577313185 0.0146599931182858 1.0 0.962706331199288 12 Q7RTS9,Q9HC07 2 +Inability to walk 0.4114686560373654 2.4126309434955497 0.0158378472819837 1.0 0.962706331199288 88 P00846,Q99720,Q7RTS9,Q5MNZ6,P07196,O60220,O00429,Q9UID3,Q9NR77,Q9GZY8,P35637,Q9H9S5,O14949,Q96D71,P61978,P42858,Q71SY5 17 +Abnormal epiphyseal ossification 0.5954657395821688 2.4078125110321147 0.0160484203799273 1.0 0.962706331199288 20 O75381,Q7RTS9,P40855,Q15125,Q2M1P5,O00116,P50542,Q14739,Q9UG56,P38435,Q96HY6 11 +Spondyloepimetaphyseal dysplasia 0.8551231651717924 2.380517173834603 0.0172883551538192 1.0 0.962706331199288 6 Q7RTS9,O95831 2 +Coxa vara 0.6577907978948149 2.3635923997690953 0.018098712776037 1.0 0.962706331199288 16 Q7RTS9,Q96AY3,Q9Y487,O75718,O95831,Q96HY6 6 +Decreased number of peripheral myelinated nerve fibers 0.6570225207555811 2.358925871897591 0.0183279164520977 1.0 0.962706331199288 16 P07196,Q9H0B6,O60333,Q9NR77,Q8TB36,P02545,P50570 7 +Generalized joint laxity 0.6835658916034716 2.3518002035007424 0.018682807047418 1.0 0.962706331199288 14 Q8NCH0,Q9UHX1 2 +Aplasia hypoplasia involving bones of the lower limbs 0.407579827101906 2.3517302975355867 0.0186863182540055 1.0 0.962706331199288 98 P55011,O95155,Q7RTS9,Q9NX62,Q96A33,Q03164,P50542,P42858,Q9UQE7,Q5JRA6,Q9H3S7,Q96AY3,P00813,Q8N0X7,Q9UHX1,Q96PZ0,O75419,Q13555,P25054,Q08J23,Q8NCM8,P13073,Q8IWS0,O95831,Q96HY6,Q7Z4L5,Q8WVQ1,Q9UGU0,O00116,Q7LGA3,Q8N3R9 31 +Pleural effusion 0.7062252300682845 2.3479954213061207 0.0188747533266775 1.0 0.962706331199288 12 Q14739,Q9UID3,Q9NZ08,P49815 4 +Peripheral demyelination 0.653126269171506 2.335222527467372 0.0195317988878829 1.0 0.962706331199288 16 P00846,P07196,Q9NR77,P03886,P07602,O43681,P50570,P42704,Q01082 9 +Postural tremor 0.6371887855335279 2.331722654362052 0.0197152862402998 1.0 0.962706331199288 17 P00846,Q9NR77,P35637,P03886 4 +Demyelinating peripheral neuropathy 0.6667762118587498 2.3313433747040486 0.0197352607988623 1.0 0.962706331199288 15 P00846,P07196,Q9Y3Z3,Q9NR77,P03886 5 +Abnormal peripheral myelination 0.580698969237508 2.319102223012137 0.0203894942667191 1.0 0.962706331199288 31 P00846,P07196,Q9H0B6,O60333,Q9NR77,P03886,Q8TB36,O43681,P02545,P07602,P50570,P42704,Q01082 13 +Atlantoaxial abnormality 0.9433965530286876 2.2869256878352164 0.0222001609659923 1.0 0.962706331199288 4 Q9NWM8,Q7RTS9 2 +Retinal telangiectasia 0.8813828581739362 2.271087352958126 0.0231416904465933 1.0 0.962706331199288 5 P03886 1 +Abnormal speech prosody 0.7861600776397191 2.266662481330542 0.0234108520304245 1.0 0.962706331199288 8 P03886 1 +Mitochondrial respiratory chain defects 0.8259803045191327 2.255709209968533 0.0240888484034289 1.0 0.962706331199288 6 P00846,P03886 2 +Hemiparesis 0.6216842075789311 2.2333662000480894 0.0255248052182628 1.0 0.962706331199288 17 P31749,O00429,Q9NZ08,P00403,P03886,O60313 6 +Limb muscle weakness 0.4136677218864718 2.2326452252563107 0.0255723492207862 1.0 0.962706331199288 85 Q9BTV4,Q7RTS9,Q9Y5P6,Q9Y4W6,P31483,P46976,P50570,Q8WXH0,P00846,P05023,P31749,O60333,Q9NR77,Q9BQT8,Q8TB36,Q14739,Q8N0X7,Q8IY17,Q13501,Q14203,Q13126,Q969G3,P35609,Q99720,O75298,P07196,P06753,Q7Z406,Q15067,P02545,Q96BR5,P50402 32 +Increased connective tissue 0.7779063381537251 2.2284284098292164 0.0258519603544244 1.0 0.962706331199288 8 P07196,P31751 2 +Scotoma 0.6556160036964538 2.1909348950484513 0.0284565041101558 1.0 0.962706331199288 14 P00846,O60220,O00429,P03886,Q8WWV3,O60313,Q9H6K4 7 +Basal ganglia calcification 0.7876249876084639 2.176378058671254 0.0295270030634937 1.0 0.962706331199288 7 O00429,O60313,Q9Y3Z3,P03886 4 +Atrophy degeneration involving the caudate nucleus 0.800806466273184 2.146443008469342 0.0318376511075608 1.0 0.962706331199288 6 P00846,P42858 2 +Sensorimotor neuropathy 0.5564839611290266 2.14498305334054 0.0319542019673524 1.0 0.962706331199288 33 P00846,Q9Y2R0,P07196,O00429,Q9NR77,P00403,P03886,O60313,O95831 9 +Low frustration tolerance 0.7104551186944691 2.115946193036012 0.0343493840988067 1.0 0.962706331199288 10 Q03164 1 +Bilateral sensorineural hearing impairment 0.5544066521677021 2.106915995707181 0.0351248618267283 1.0 0.962706331199288 25 P55011,Q13501,Q7Z406,Q15067,P00403,P03886,P35637,O43681,P38159,Q01082 10 +Mitochondrial inheritance 0.8364719794137447 2.085814506506498 0.0369954288595635 1.0 0.962706331199288 5 P00846,P03886 2 +Achilles tendon contracture 0.6580171207169924 2.084274053672173 0.0371352460593781 1.0 0.962706331199288 12 P02545,O60313,Q9H9S5,Q8TD16,Q08J23,P50402,Q8WXH0 7 +Aplasia hypoplasia of the capital femoral epiphysis 0.7671052937694764 2.083464511726911 0.0372089032472371 1.0 0.962706331199288 7 Q7RTS9 1 +Absent epiphyses 0.7441563069966377 2.070355817883877 0.0384190360617715 1.0 0.962706331199288 8 Q7RTS9 1 +Abnormal circulating citrulline concentration 0.8324622887911597 2.069093711178694 0.038537293763579 1.0 0.962706331199288 5 P03886 1 +Papule 0.5805176977469539 2.0645213849266506 0.0389683084471055 1.0 0.962706331199288 18 Q92990,P31749,Q9NZ08,P16615,O75844,P38435 6 +Progressive external ophthalmoplegia 0.6987440673325487 2.0562701458740347 0.0397564842416857 1.0 0.962706331199288 10 O60313,P03886 2 +Punctate cataract 0.8832635792952943 2.050526975998984 0.0403130341352555 1.0 0.962706331199288 4 Q8WWV3,P08670 2 +Abnormal auditory evoked potentials 0.6958798195265841 2.0416158601613312 0.04118965081277 1.0 0.962706331199288 10 Q9NSV4,O60220,P07196,Q15125,O60313 5 +Centrocecal scotoma 0.8791435537273048 2.034122225032452 0.0419392736503114 1.0 0.962706331199288 4 P00846,P03886 2 +Personality changes 0.575707929066941 2.0320808254805924 0.0421454741906202 1.0 0.962706331199288 18 Q13501,O60220,P49770,P00403,P03886,P31483,P42858,Q8IY17 8 +Horizontal nystagmus 0.5435943424735908 2.0267811380317906 0.0426848002748427 1.0 0.962706331199288 24 P00846,O00429,O60313,Q969F9,P07602,O15020,O95831 7 +Pulmonary embolism 0.8770004877507612 2.0255788827688717 0.0428079573500439 1.0 0.962706331199288 4 Q9NZ08 1 +Abnormal greater sciatic notch morphology 0.7707038077544275 2.014028515772581 0.0440065397022901 1.0 0.962706331199288 6 Q7RTS9 1 +Blurred vision 0.8184346212591482 2.0103696978611474 0.0443920751435094 1.0 0.962706331199288 5 P03886 1 +Capillary hemangioma 0.7258972207715941 1.9836891636806924 0.0472905023295131 1.0 0.962706331199288 8 Q7LGA3,Q9UHX1,P31749 3 +Vascular tortuosity 0.9618838696914008 1.982773860419212 0.0473926950633982 1.0 0.962706331199288 3 P03886 1 +Metatarsus valgus 0.8648108932080104 1.9768525777936004 0.0480582965250804 1.0 0.962706331199288 4 Q9H9S5 1 +Abnormal subcutaneous fat tissue distribution 0.8646201620600276 1.9760883797957909 0.0481447682824591 1.0 0.962706331199288 4 Q9Y487 1 +Proximal amyotrophy 0.6062325506475628 1.9671630794531425 0.0491644129494888 1.0 0.962706331199288 15 P07196,P35637,Q9H9S5,P50402,Q8WXH0 5 +Polyneuropathy 0.580503260422036 1.967042122961865 0.0491783547733315 1.0 0.962706331199288 17 P00846,O95721,P03886,O60313,O95831 5 +Onion bulb formation 0.7408297451834436 1.963111153140482 0.0496332598804254 1.0 0.962706331199288 7 P07196,O60333,Q9NR77,Q8TB36,P50570 5 +Slow decrease in visual acuity 0.7007848148589948 1.9594989086043952 0.0500543875733314 1.0 0.962706331199288 9 P00846,P03886,P31749 3 +Peripheral hypermyelination 0.9552391474575646 1.957398172888123 0.0503006731464072 1.0 0.962706331199288 3 Q9NR77 1 +Supraventricular tachycardia 0.7394792457451608 1.9568841293286925 0.0503610928906932 1.0 0.962706331199288 7 P35609,Q8NFF5,Q99996,Q14BN4 4 +Polar cataract 0.805094786729852 1.9542015020739831 0.0506773917596321 1.0 0.962706331199288 5 Q7LGA3,P25054,P08670,Q9Y287 4 +Aplasia hypoplasia involving bones of the feet 0.4278017996333405 1.953621647162814 0.0507459786480279 1.0 0.962706331199288 77 P55011,O95155,Q7RTS9,Q9NX62,Q96A33,Q03164,P42858,Q9UQE7,Q5JRA6,Q9H3S7,O95202,P00813,Q8N0X7,Q9UHX1,Q96PZ0,Q13555,P25054,Q08J23,Q8NCM8,P13073,Q8IWS0,P21281,Q7Z4L5,Q8WVQ1,Q9UGU0,P02545,Q7LGA3,Q8N3R9 28 +Abnormal metatarsal morphology 0.5322349413727193 1.9512501522875505 0.0510272956401536 1.0 0.962706331199288 32 Q7RTS9,Q8WVQ1,P31749,Q15392,Q9H9S5,Q08J23,Q03252,P50542,P16435 9 +Hypoglycemic seizures 0.7380643902075443 1.950356102417976 0.0511336901393291 1.0 0.962706331199288 7 P31751 1 +Corneal erosion 0.8577794072170307 1.94864395127129 0.0513379595272043 1.0 0.962706331199288 4 Q96EK5 1 +Short middle phalanx of finger 0.8557409042537361 1.9404523131596816 0.0523247442222332 1.0 0.962706331199288 4 Q03164 1 +Abnormality of the achilles tendon 0.6123557847392688 1.9362626463852943 0.052835541239717 1.0 0.962706331199288 14 P02545,O60313,Q9H9S5,Q8TD16,Q08J23,P50402,Q8WXH0 7 +Broad palm 0.7156165388463944 1.9345437383897992 0.0530463098100963 1.0 0.962706331199288 8 Q7RTS9,O95831 2 +Supraventricular arrhythmia 0.5451483552494067 1.9277267103960307 0.0538891279309681 1.0 0.962706331199288 19 P00846,P35609,P02545,P50402,Q99996,Q14BN4,Q8WXH0,Q8NFF5 8 +Arterial thrombosis 0.7324067313681253 1.9242087142825417 0.0543284272718376 1.0 0.962706331199288 7 Q9NZ08 1 +Disproportionate short trunk short stature 0.7979172672885197 1.9238518063413628 0.0543731615618128 1.0 0.962706331199288 5 Q7RTS9 1 +Abnormality of thyroid physiology 0.403153763552725 1.9158123840742416 0.0553889808490886 1.0 0.962706331199288 82 O95155,Q9Y3Z3,P31749,O00429,Q13423,P25054,P00403,P03886,O60313,P61978,Q13868,O95470,P49815,P00813 14 +Lacticaciduria 0.7291698441155069 1.909218076273729 0.0562339653722196 1.0 0.962706331199288 7 P00846,Q9P0J1,P03886 3 +Abnormality of the pulmonary veins 0.7456268089812996 1.9022931231938776 0.0571328442170622 1.0 0.962706331199288 6 Q15392 1 +Posterior fossa cyst 0.9407146873823978 1.9017549315895637 0.0572032007482095 1.0 0.962706331199288 3 Q9UHX1 1 +Impaired vibration sensation in the lower limbs 0.6163921589619217 1.9009164746144296 0.0573129538445527 1.0 0.962706331199288 13 P00846,Q9NR77,Q9H0B6 3 +Areflexia of lower limbs 0.5254613639256583 1.898215189017442 0.0576677407530155 1.0 0.962706331199288 21 P07196,Q9NR77,Q15067,O60313,Q9H6K4 5 +Mixed demyelinating and axonal polyneuropathy 0.8447264560268701 1.896086558173703 0.0579485997280437 1.0 0.962706331199288 4 P07196,P03886 2 +Talipes calcaneovalgus 0.7895009177811092 1.8881514332596023 0.0590056236785039 1.0 0.962706331199288 5 Q9NR77 1 +Distal lower limb amyotrophy 0.6141298073645892 1.8877486127633052 0.0590597067953519 1.0 0.962706331199288 13 Q8TD16,Q9NR77,P07196,Q9H0B6 4 +Hypoplasia of the musculature 0.789169750550054 1.886744238795365 0.059194734358376 1.0 0.962706331199288 5 Q9Y487,Q9NR77 2 +Abnormal full field electroretinogram 0.7240168462024763 1.8853072915697304 0.059388362288947 1.0 0.962706331199288 7 P00846 1 +Abnormal light and dark adapted electroretinogram 0.7240168462024763 1.8853072915697304 0.059388362288947 1.0 0.962706331199288 7 P00846 1 +Brushfield spots 0.7885450799373357 1.8840893887866352 0.0595528853117395 1.0 0.962706331199288 5 O75381,P40855,P50542 3 +Hyperextensible skin 0.6013039738249303 1.8701142114276963 0.0614679593972329 1.0 0.962706331199288 14 Q9NWM8,Q9UHX1 2 +Toe walking 0.5223037341927002 1.8687728160190145 0.0616544283980435 1.0 0.962706331199288 23 Q99720,P06753,P35637,Q8TD16,O43681,P02545,P07602,Q9H9S5,P50402,Q8WXH0,O95831,Q01082 12 +Contractures of the joints of the upper limbs 0.3992476141763459 1.8664176290745629 0.0619829585596807 1.0 0.962706331199288 82 Q99720,O95155,P07196,P06753,Q96AY3,Q9NR77,P35637,Q15392,O75844,Q7LGA3,P50402,Q99567,P16435,Q8WXH0,Q71SY5 15 +Neoplasm of the male external genitalia 0.6409915621450533 1.8663186233784343 0.061996800747847 1.0 0.962706331199288 11 Q13423,P31749 2 +Abnormal waist to hip ratio 0.7194392802334201 1.8640193210747351 0.0623189911093344 1.0 0.962706331199288 7 P43304,P31751 2 +Symptomatic seizures 0.7000494420256396 1.8596594792556995 0.062933718363604 1.0 0.962706331199288 8 P31751 1 +Abnormal middle phalanx morphology of the hand 0.6997101949801144 1.8580213807658297 0.0631659781328923 1.0 0.962706331199288 8 Q03164,Q8IWS0,Q15233,Q9UHX1 4 +Abnormal delivery 0.5196051769392164 1.8462691448057464 0.0648531355543087 1.0 0.962706331199288 24 Q9H3S7,P06753,Q9NQX3,Q9Y487,O60313,Q969X5,Q96EY7,P02545,O75718,O75844,P50570,Q01082,P33991 13 +Lower limb amyotrophy 0.5483683359002376 1.84569950988926 0.0649358484290296 1.0 0.962706331199288 18 O75298,P07196,Q9H0B6,Q9NR77,Q8TD16 5 +Oromandibular dystonia 0.8316677148653655 1.8432624615458653 0.0652906991082753 1.0 0.962706331199288 4 Q99720,P35637 2 +Hyperactive deep tendon reflexes 0.676568054278376 1.8385479499596191 0.0659817030125684 1.0 0.962706331199288 9 O00429,Q9NR77,Q9H0W8 3 +Fibrosarcoma 0.9234071572630128 1.8351481138524055 0.0664837466034007 1.0 0.962706331199288 3 Q13126 1 +Hemiplegia hemiparesis 0.5107645424737309 1.8278916929332596 0.0675658080359589 1.0 0.962706331199288 40 O95155,Q9Y3Z3,P31749,O00429,Q9NZ08,P00403,P03886,O60313,Q9H9S5,Q8IY17 10 +Buphthalmos 0.8271801137534206 1.825054952130474 0.0679927371965227 1.0 0.962706331199288 4 Q9H9S5 1 +Aplasia hypoplasia involving the skeletal musculature 0.6539042894842556 1.824252987121955 0.0681138342879077 1.0 0.962706331199288 10 Q9Y487,Q9NR77,Q9H9S5 3 +Furrowed tongue 0.7107685244232309 1.8235755808328449 0.0682162610737329 1.0 0.962706331199288 7 P61978,Q71SY5,P31749 3 +Abnormality of tibia morphology 0.5825002085747065 1.8205864529717903 0.0686697436433372 1.0 0.962706331199288 15 Q7RTS9,O95831,Q32P28,P16435 4 +Limited elbow extension 0.6110817388139683 1.820034891188533 0.0687536916018489 1.0 0.962706331199288 12 Q7RTS9,Q9H6K4 2 +Astrocytosis 0.6908478961776311 1.8151368645720292 0.0695028791947676 1.0 0.962706331199288 8 P00846,P49815 2 +Hemoptysis 0.7712630381047356 1.8103842993089487 0.0702362123748974 1.0 0.962706331199288 5 Q9NZ08 1 +Psychomotor deterioration 0.6703895733843287 1.8074580808337128 0.0706908850513905 1.0 0.962706331199288 9 Q03164 1 +Deep plantar creases 0.7704955744879531 1.8070999030243933 0.0707467037837998 1.0 0.962706331199288 5 Q9Y487,P61978,O00170 3 +Abnormal sputum 0.7239746608517735 1.8048118524232457 0.0711041290492737 1.0 0.962706331199288 6 Q9NZ08 1 +Absent brainstem auditory responses 0.822031256675451 1.804130905494181 0.0712107878098122 1.0 0.962706331199288 4 O60313,P07196 2 +Enlarged ovaries 0.7666439907557574 1.7906026788714022 0.0733570768582063 1.0 0.962706331199288 5 P16435,P31749 2 +Abnormal circulating long chain fatty acid concentration 0.7203677486918125 1.7884855411466083 0.0736977063401949 1.0 0.962706331199288 6 O75381,P40855,P50542 3 +External ophthalmoplegia 0.5387435074840949 1.7793042178378873 0.0751898998434554 1.0 0.962706331199288 18 P00403,Q9GZY8,P03886,O60313,P50570 5 +Abnormal muscle fiber protein expression 0.700762242632147 1.776710184421928 0.075615935778174 1.0 0.962706331199288 7 Q9Y5P6,P02545,Q9H9S5,P50402,Q8WXH0 5 +Anomalous trichromacy 0.9070455891059792 1.7718985388104624 0.0764114010279546 1.0 0.962706331199288 3 O60313,O00429 2 +Tritanomaly 0.9070455891059792 1.7718985388104624 0.0764114010279546 1.0 0.962706331199288 3 O60313,O00429 2 +Retrocollis 0.9063875043717018 1.7693490960072416 0.0768356349389247 1.0 0.962706331199288 3 Q99720 1 +Progressive gait ataxia 0.6020246139910485 1.7682262153538473 0.0770230932627975 1.0 0.962706331199288 12 P00846,O43681,Q05086,O15020 4 +Stroke like episode 0.7155374201445441 1.7665834840225112 0.0772980089658261 1.0 0.962706331199288 6 P00403,P03886 2 +Episodic respiratory distress 0.904058952313093 1.760324931458635 0.0783527293127355 1.0 0.962706331199288 3 P03886 1 +Abnormal csf protein level 0.6004672538323821 1.7592921616888686 0.0785278972664498 1.0 0.962706331199288 12 P55011,Q9NR77,P00403,P03886,P07602,O43681 6 +Abnormality of the tonsils 0.6606380871601147 1.758203456347691 0.0787128973601853 1.0 0.962706331199288 9 P31751 1 +Type 1 muscle fiber atrophy 0.6950322410247156 1.7497824611787631 0.0801558582058175 1.0 0.962706331199288 7 P06753,P02545,P50402,P61978,Q8WXH0 5 +Thoracic kyphosis 0.5476758534695455 1.7496066879328622 0.0801862049090516 1.0 0.962706331199288 17 Q7RTS9,O95831,Q9UHX1,P51648 4 +Abnormality of the musculature of the lower limbs 0.5073959690569085 1.749083249009793 0.0802766303012101 1.0 0.962706331199288 27 P00846,P07196,Q9NR77,Q9H9S5,P50402 5 +Schizophrenia 0.5056456260392748 1.7458224507750388 0.0808418085282773 1.0 0.962706331199288 22 Q9BUK6,O00192,Q92890,O76024,P07602,O43681,P16615,P21964,Q04637,Q9BQE5,Q96QK1,Q9NTZ6 12 +Cystic liver disease 0.7556916196933671 1.743564008942278 0.0812351437573823 1.0 0.962706331199288 5 Q7Z4L5 1 +Lipodystrophy 0.5045404842503761 1.7386908673255193 0.0820891533134731 1.0 0.962706331199288 34 P28070,Q9Y3Z3,P31751,Q9Y487,O75844,P50402,P09493,Q8WXH0 8 +Difficulty walking 0.397545317777028 1.7377350977856303 0.0822575013285125 1.0 0.962706331199288 80 P00846,Q99720,Q7RTS9,O75298,Q9Y3Z3,Q9H0B6,P31749,O00429,P06753,Q9NR77,Q15067,P35637,Q8TD16,Q9H9S5,P42858,Q71SY5,Q9BPX6 17 +Metaphyseal striations 0.6920300176553702 1.7356478699156288 0.0826261162201045 1.0 0.962706331199288 7 P00813 1 +Ovarian cyst 0.531652821379047 1.7301411436676406 0.0836050608375673 1.0 0.962706331199288 18 P31749,P78549,P31751,P02545,Q03252,P16435,Q15437,Q9Y4P3 8 +Abnormal iris pigmentation 0.5042767437654824 1.729388406030257 0.0837396036357045 1.0 0.962706331199288 24 O75381,O95155,P40855,P31749,Q86YV9,Q05086 6 +Abnormality of the carpal bones 0.531402055338405 1.7283986771078743 0.0839167725116967 1.0 0.962706331199288 18 P16435,Q7RTS9,P25054,Q15125 4 +Dysesthesia 0.7070026352127274 1.7277796910027916 0.0840277298058707 1.0 0.962706331199288 6 Q9NR77 1 +Congenital nystagmus 0.5017934082397921 1.72516611900645 0.084497539642951 1.0 0.962706331199288 20 P55011,P00846,Q9H3S7,Q96PZ0,Q7LGA3,P42858,Q8N3R9 7 +External ear malformation 0.5307413105109505 1.723806217366102 0.0847428318496228 1.0 0.962706331199288 18 O75381,P40855,Q00577,Q8NCH0,Q15555,P32929,P50542,Q9BXW9 8 +Type ii lissencephaly 0.7050921513652042 1.71907558920348 0.085600609024607 1.0 0.962706331199288 6 Q9H9S5,P07942 2 +Abnormality of the distal phalanges of the toes 0.6882025426738342 1.7176025421013144 0.0858691363406785 1.0 0.962706331199288 7 O75844,Q7LGA3,Q71SY5 3 +Episodic vomiting 0.5848864798953846 1.716019127646661 0.086158541595303 1.0 0.962706331199288 13 P00846,P22695,P00403,P03886,P61978 5 +Abnormal chorioretinal morphology 0.5028981328107203 1.7150167341244578 0.0863421589107367 1.0 0.962706331199288 30 O75381,P40855,Q9Y619,P31749,O60826,Q96AX1,Q9H9S5,P50542,Q10713,P49815,Q9Y5Y5,Q8IY17,Q01082 13 +Abnormal platelet morphology 0.686829574598997 1.7111225607697065 0.0870584902072804 1.0 0.962706331199288 7 P12814,Q86YV9,Q969F9 3 +Thyroiditis 0.6506570067351128 1.707559843474152 0.0877180448405015 1.0 0.962706331199288 9 P00813,P31749 2 +Abnormal enchondral ossification 0.5011253402615322 1.7075348516604492 0.0877226856926156 1.0 0.962706331199288 33 O75381,Q7RTS9,P40855,Q8WVQ1,O95202,Q15125,Q2M1P5,O00116,P50542,Q8NCM8,Q14739,Q9UG56,P38435,Q96HY6 14 +Aplasia hypoplasia of toe 0.4981129553185502 1.707302924905181 0.0877657627538455 1.0 0.962706331199288 38 P55011,Q5JRA6,Q9H3S7,Q96PZ0,Q9NX62,P25054,Q03164,Q8N3R9,Q7LGA3,P42858,P13073,Q8IWS0,P00813,Q9UHX1 14 +Undetectable light and dark adapted electroretinogram 0.7975134925310208 1.7040225933753088 0.0883768663837827 1.0 0.962706331199288 4 P00846 1 +Hypoplasia of the odontoid process 0.700818691370669 1.6995824430275714 0.0892094950937059 1.0 0.962706331199288 6 Q7RTS9 1 +Skin appendage neoplasm 0.699714595783506 1.6945409664545152 0.0901625339853122 1.0 0.962706331199288 6 Q15437,P25054 2 +St segment elevation 0.7937762948092061 1.6886979308783516 0.0912773323706137 1.0 0.962706331199288 4 Q99996,Q14BN4 2 +Abnormal st segment 0.7937762948092061 1.6886979308783516 0.0912773323706137 1.0 0.962706331199288 4 Q99996,Q14BN4 2 +Retinal vascular tortuosity 0.5382590707506856 1.6864428522278432 0.0917105335576524 1.0 0.962706331199288 17 P00846,P03886 2 +Barrel shaped chest 0.7416973710917123 1.6831969297799676 0.0923369749850235 1.0 0.962706331199288 5 Q7RTS9,Q32P28 2 +Muscle hypertrophy of the lower extremities 0.6457167666573794 1.6824098275321224 0.0924893970246907 1.0 0.962706331199288 9 P50570,Q9NR77,Q9Y5P6,Q9H9S5 4 +Corneal ulceration 0.7410165740348669 1.6802528859031574 0.0929081235492292 1.0 0.962706331199288 5 Q96EK5,O75844,P06132 3 +Nemaline bodies 0.7906760781577025 1.6759728194887424 0.0937435167107763 1.0 0.962706331199288 4 O43676,P07196 2 +Aplasia hypoplasia of the scapulae 0.790275988108315 1.674329804285595 0.0940658001044087 1.0 0.962706331199288 4 Q7RTS9 1 +Wide anterior fontanel 0.4975921574278414 1.6722529141613838 0.0944744602642846 1.0 0.962706331199288 29 O75381,P40855,Q15125,Q9Y487,O75419,Q2M1P5,Q32P28,O75718,Q08J23,P50542,P16435,Q9H0W8 12 +Abnormality of lower limb epiphysis morphology 0.5232495282128558 1.6716125156578778 0.0946007551860397 1.0 0.962706331199288 18 Q7RTS9,Q7LGA3 2 +Peripheral axonal degeneration 0.4352495124420562 1.671187982255354 0.0946845532541897 1.0 0.962706331199288 68 Q9H0B6,O15269,Q9Y4W6,Q9NVI7,P03886,O60313,P50570,Q9BPX6,P00846,O60333,Q9BQT8,Q8TB36,Q8IY17,P00403,O95831,Q6DKK2,P07196,Q15067,P02545,P07602,Q96BR5,Q01433 22 +Retinal detachment 0.5345972478636245 1.661791010252442 0.0965546853644625 1.0 0.962706331199288 17 Q8NCH0,Q9H9S5 2 +Metaphyseal widening 0.493263058915769 1.6607980252475372 0.0967540179164414 1.0 0.962706331199288 20 Q7RTS9,Q8NCM8,Q14739,O95831,Q96HY6 5 +Myositis 0.6410943460222818 1.6588290308228415 0.0971502486507718 1.0 0.962706331199288 9 P28070,Q9NZ08 2 +Bruising susceptibility 0.4948886952957143 1.652746518755529 0.0983824626296527 1.0 0.962706331199288 31 Q8NCH0,Q13126,Q969F9,Q9NWM8,P38435 5 +Abnormal circulating non proteinogenic amino acid concentration 0.6574476769894964 1.6519870107811785 0.0985371988012193 1.0 0.962706331199288 8 P03886 1 +Incomitant strabismus 0.5193599188579946 1.6444273396917275 0.1000879616512495 1.0 0.962706331199288 18 P55011,Q9H3S7,Q96PZ0,O00429,O60313,Q7LGA3,P42858,Q8N3R9 8 +Metaphyseal irregularity 0.5802133002925618 1.6424395317412572 0.1004989479907554 1.0 0.962706331199288 12 Q7RTS9 1 +Tibial bowing 0.6880117964564394 1.6409758898018496 0.1008024201222572 1.0 0.962706331199288 6 Q7RTS9 1 +Zonular cataract 0.5789753881425033 1.635258819746168 0.10199480231898 1.0 0.962706331199288 12 Q8WWV3,P08670 2 +Progressive sensorineural hearing impairment 0.598678713196824 1.6337851753287878 0.1023039662092555 1.0 0.962706331199288 11 O60313,O60220,P03886,P00403 4 +Premature rupture of membranes 0.6855887026338242 1.6298565205721154 0.1031318248548927 1.0 0.962706331199288 6 Q9Y487 1 +Aplasia hypoplasia of the palmar creases 0.870031365948494 1.627915144933529 0.1035428796272679 1.0 0.962706331199288 3 Q8NCH0 1 +Generalized hyperpigmentation 0.5768238920004157 1.622768463667035 0.1046389096285445 1.0 0.962706331199288 12 Q13423,P51648 2 +Abnormality of krebs cycle metabolism 0.7276629774874819 1.622376090316562 0.1047228454160449 1.0 0.962706331199288 5 P03886 1 +Abnormal choroid morphology 0.4910154025689718 1.6217521667537844 0.1048564240764167 1.0 0.962706331199288 31 O75381,P40855,Q9Y619,P31749,O60826,Q96AX1,Q9H9S5,P50542,Q10713,P49815,Q9Y5Y5,Q8IY17,Q01082 13 +Abnormal skin morphology of the palm 0.3564514452182827 1.619870718560218 0.1052600510408399 1.0 0.962706331199288 100 P40855,O75381,P31749,O95721,Q99567,Q14739,Q01082,Q8IY17,Q9UHX1,Q8NCH0,Q9Y487,P25054,P61978,P09493,Q71SY5,P35609,Q9UID3,Q06136,P16615 19 +Limb joint contracture 0.3629504791740311 1.6196247069877148 0.1053129189172112 1.0 0.962706331199288 110 O95155,O60313,Q8WXH0,Q96AY3,Q9NR77,Q8TD16,Q15392,Q99567,Q86XL3,P16435,Q71SY5,Q99720,P07196,P06753,P35637,Q9H9S5,O75844,Q7LGA3,P50402 19 +Hepatic cysts 0.7758529945148505 1.6149809305318934 0.1063148245524707 1.0 0.962706331199288 4 Q7Z4L5 1 +Genu varum 0.5592408690114465 1.6145534813181606 0.1064074262596888 1.0 0.962706331199288 14 Q7RTS9 1 +Delayed cranial suture closure 0.4889136818696905 1.6065475781020713 0.1081536499605726 1.0 0.962706331199288 32 O75381,O95155,P40855,Q8NCH0,Q9Y487,Q32P28,O75844,P16435 8 +Morphological abnormality of the pyramidal tract 0.4863977068027034 1.603621788986342 0.1087974449238107 1.0 0.962706331199288 21 P00846,Q13045,Q13501,O75298,Q14203,Q9UBB4,O95831,P35637,Q9Y4P3,Q15056 10 +Muscle stiffness 0.5258681945698989 1.602830520391485 0.1089720766108532 1.0 0.962706331199288 17 P00846,Q15392,Q9Y3Z3 3 +Mania 0.557216850078473 1.602113815528158 0.1091304434779401 1.0 0.962706331199288 14 P16615,P00403,P03886 3 +Spinal cord compression 0.7222300637553016 1.5987604981559098 0.1098738293309957 1.0 0.962706331199288 5 P25054,P31749 2 +Profound hearing impairment 0.722082253053141 1.5981174688750186 0.1100168365831399 1.0 0.962706331199288 5 Q9NR77 1 +Abnormal placental size 0.7713292065282303 1.5963203716200984 0.1104172841034585 1.0 0.962706331199288 4 Q6PGP7,O75844 2 +Cns demyelination 0.5647163483565143 1.596010169776087 0.1104865228109588 1.0 0.962706331199288 13 P40855,P49770,Q15067,P42704,P51648 5 +Increased serum pyruvate 0.4866729146386279 1.5935430082647997 0.1110384280909944 1.0 0.962706331199288 34 Q70HW3,Q9BWD1,P22695,O95831,P03886,Q5JRX3,O96000,O43676,Q86Y39 9 +Sensory axonal neuropathy 0.5640691229768617 1.5921395893810766 0.1113533433773044 1.0 0.962706331199288 13 Q15067,Q9H0B6 2 +Fibrous tissue neoplasm 0.4858519171810541 1.587425785473176 0.1124162431106552 1.0 0.962706331199288 24 P31749,Q13126,P25054,Q15392,P16220,P49815,Q01082 7 +Postaxial foot polydactyly 0.5899990349778553 1.585495766418009 0.1128537380510721 1.0 0.962706331199288 11 Q7Z4L5,Q14739,O75845,Q8NCM8,Q10713 5 +Abnormality of the 5th toe 0.5899990349778553 1.585495766418009 0.1128537380510721 1.0 0.962706331199288 11 Q7Z4L5,Q14739,O75845,Q8NCM8,Q10713 5 +Very long chain fatty acid accumulation 0.6600003932690595 1.583801410878919 0.1132389181398376 1.0 0.962706331199288 7 O75381,P40855,P50542 3 +Optic nerve hypoplasia 0.4834897776244021 1.5814134919293183 0.1137835245581049 1.0 0.962706331199288 21 Q9H3S7,P07196,Q9Y5P6,O75312,Q9H9S5,P61978,Q15058,Q9UHX1 8 +First degree atrioventricular block 0.7662759623212724 1.5754515493298704 0.1151522536136999 1.0 0.962706331199288 4 Q99996,Q14BN4 2 +Chorioretinal coloboma 0.658150032240844 1.5749739109494303 0.1152624666304138 1.0 0.962706331199288 7 Q10713,Q01082,P31749 3 +Centrally nucleated skeletal muscle fibers 0.6736476860883398 1.5749235196591425 0.1152740990415797 1.0 0.962706331199288 6 Q9BPX6,P06753,P50570 3 +Fibroadenoma of the breast 0.716624874607293 1.574356736005165 0.1154049999443238 1.0 0.962706331199288 5 P31749 1 +Vitiligo 0.657798562819226 1.57329652026566 0.1156501747093894 1.0 0.962706331199288 7 P03886 1 +Abnormality of the nasolabial region 0.6731735631876576 1.572737830419922 0.1157795363155069 1.0 0.962706331199288 6 Q8NCH0 1 +Prominent nasolabial fold 0.6731735631876576 1.572737830419922 0.1157795363155069 1.0 0.962706331199288 6 Q8NCH0 1 +Mild short stature 0.7652930253089711 1.571389343222522 0.1160922398122781 1.0 0.962706331199288 4 Q14739,Q8WVQ1 2 +Nasogastric tube feeding in infancy 0.6059149130010781 1.570139980408945 0.1163825491053773 1.0 0.962706331199288 10 P61978,P06753,Q9UHX1 3 +Male reproductive system neoplasm 0.5322533596738779 1.569529615331629 0.1165245843586586 1.0 0.962706331199288 16 Q13423,P25054,P31749 3 +Multiple glomerular cysts 0.9908256880733944 1.5691819771561395 0.1166055424848497 1.0 0.962706331199288 2 P03886 1 +Retinal arterial tortuosity 0.9908256880733944 1.5691819771561395 0.1166055424848497 1.0 0.962706331199288 2 P03886 1 +Low plasma citrulline 0.9908256880733944 1.5691819771561395 0.1166055424848497 1.0 0.962706331199288 2 P03886 1 +Leber optic atrophy 0.9908256880733944 1.5691819771561395 0.1166055424848497 1.0 0.962706331199288 2 P03886 1 +Hypoglycemic coma 0.6235355023722724 1.5688428710104465 0.1166845562305396 1.0 0.962706331199288 9 P31751 1 +Duplication involving bones of the feet 0.4842121388428264 1.5677909182860166 0.1169299350521801 1.0 0.962706331199288 27 Q7Z4L5,O95155,Q15125,Q14739,O75845,Q2M1P5,Q8WXW3,P21964,Q8NCM8,Q10713 10 +Anterior rib cupping 0.7148190509167216 1.5664863314672188 0.1172348060324148 1.0 0.962706331199288 5 P00813 1 +Abnormal endocrine physiology 0.7145791049660507 1.5654402675148291 0.1174797128908475 1.0 0.962706331199288 5 Q13423 1 +Wormian bones 0.4944673162672558 1.5623693926382205 0.1182009931947569 1.0 0.962706331199288 19 Q96AY3,Q9Y487,Q32P28,O75844,O95831 5 +Abnormal blood potassium concentration 0.5588356950304715 1.560799433224341 0.1185710812271456 1.0 0.962706331199288 13 Q13423,Q99996,P0DP25,O00170 4 +Peripheral axonal neuropathy 0.4630307579444594 1.5580516903543429 0.1192209952850225 1.0 0.962706331199288 52 P00846,P07196,Q9H0B6,Q9Y4W6,Q9NVI7,Q15067,Q01433,P00403,P03886,O60313,P07602,Q96BR5,O95831,Q8IY17,Q9BPX6 15 +Ventricular preexcitation 0.6376957380588899 1.554454681559358 0.1200759985719586 1.0 0.962706331199288 8 P00846,P00403,P03886 3 +Angioid streaks of the fundus 0.8511681930826138 1.554141226737818 0.12015073314631 1.0 0.962706331199288 3 P31749 1 +Profound sensorineural hearing impairment 0.7611077622281778 1.5540826184427994 0.1201647107030512 1.0 0.962706331199288 4 Q9NR77 1 +Abnormal acetabulum morphology 0.4798668048058837 1.553695385809044 0.1202570942384064 1.0 0.962706331199288 21 Q96AY3,O75718,Q7RTS9,Q8NCM8 4 +Posterior embryotoxon 0.4800643801131 1.5504083041078678 0.1210435466751707 1.0 0.962706331199288 22 O75381,P40855,P21964,Q96DF8,Q7LGA3,P50542,Q9Y4P3,Q9Y5Y5 8 +Vertebral fusion 0.5836764741066981 1.5502046519764083 0.1210924036359948 1.0 0.962706331199288 11 Q9UHX1 1 +Submucous cleft of soft and hard palate 0.4814963578780946 1.5463974687863011 0.1220086050995992 1.0 0.962706331199288 27 O75419,Q15392,Q9H9S5,Q96DF8,Q08J23,O75844,Q7LGA3 7 +Extrapyramidal muscular rigidity 0.7094411121785017 1.5430244061314182 0.1228248543601049 1.0 0.962706331199288 5 Q9H6K4,Q9BPX6 2 +Macrogyria 0.6514347427371736 1.54289054710295 0.1228573347649899 1.0 0.962706331199288 7 Q15392 1 +Ulnar claw 0.7583050274396348 1.542483875981528 0.1229560531838729 1.0 0.962706331199288 4 Q9NR77 1 +Atlantoaxial instability 0.983722994968926 1.541345888665783 0.1232326260836056 1.0 0.962706331199288 2 Q7RTS9 1 +Heterochromia iridis 0.8476705365712223 1.5404382716202762 0.1234535585398148 1.0 0.962706331199288 3 P31749 1 +Epiphyseal dysplasia 0.6659568114939471 1.5394278071953829 0.1236998897845615 1.0 0.962706331199288 6 Q7RTS9 1 +Posterior polar cataract 0.8472468916518583 1.538778088286183 0.1238584809416418 1.0 0.962706331199288 3 P25054,P08670 2 +Aplasia hypoplasia involving bones of the thorax 0.4762975392960599 1.5375249011350258 0.1241648219943374 1.0 0.962706331199288 40 Q7Z4L5,O95155,Q7RTS9,O75419,P98175,Q03164,O75844,P16435,Q8NCM8,Q14739,Q96HY6,Q9UHX1 12 +Asymmetric growth 0.5374994661788206 1.5372310403242735 0.1242367416327299 1.0 0.962706331199288 15 O95155,P31749,Q15125,P31751 4 +Deep palmar crease 0.5621376294476236 1.5371720169177032 0.1242511909687671 1.0 0.962706331199288 12 Q9Y487,P98175,P61978,O00170,P21281 5 +Hand polydactyly 0.4776163327755198 1.5360933254644056 0.124515493050628 1.0 0.962706331199288 38 Q7Z4L5,Q15125,O95202,Q14739,O75845,Q15067,P98175,Q2M1P5,O60826,Q8WXW3,P21964,Q8NCM8,Q9BXW9,Q10713,Q9UPP1,Q8IY17,Q9UHX1 17 +Protrusio acetabuli 0.8454798301895246 1.531852304321783 0.1255588855664862 1.0 0.962706331199288 3 Q96AY3 1 +Epidermoid cyst 0.7554125359033675 1.5305063808198711 0.1258914352703484 1.0 0.962706331199288 4 P25054 1 +Cutaneous cyst 0.7554125359033675 1.5305063808198711 0.1258914352703484 1.0 0.962706331199288 4 P25054 1 +Severe global developmental delay 0.4063588409913114 1.5301324000163643 0.1259839598564973 1.0 0.962706331199288 73 P55011,Q7RTS9,P40855,Q9BT22,Q96A33,P03886,P07942,P42858,P00846,O75381,Q9H3S7,O75312,Q96PZ0,Q00577,Q71SY5,Q9UID3,Q15067,Q7LGA3,Q8N3R9 19 +Shoulder girdle muscle weakness 0.5535293781882162 1.5289467909145562 0.1262776352255079 1.0 0.962706331199288 13 P06753,P07602,Q8TD16,Q9H9S5,O14979 5 +Insidious onset 0.7544803348061142 1.526644693535044 0.1268493869891311 1.0 0.962706331199288 4 Q9NR77 1 +Abnormality of circulating leptin level 0.7544544821605905 1.526537587160403 0.1268760370354655 1.0 0.962706331199288 4 P31751 1 +Acanthosis nigricans 0.5975149006417648 1.5251123908246638 0.1272310671707226 1.0 0.962706331199288 10 P31751 1 +Upper limb muscle weakness 0.4784789135558164 1.5225920872928005 0.1278607906469688 1.0 0.962706331199288 27 Q9BTV4,P00846,P07196,Q9Y5P6,P31749,P02545,P50402,P46976,Q969G3,P50570,Q8WXH0,Q8N0X7 12 +Abnormal platelet granules 0.842991560386759 1.5220971497546945 0.1279847400771112 1.0 0.962706331199288 3 Q969F9 1 +Myotonia 0.6459324306794497 1.5165495311192416 0.1293804558460185 1.0 0.962706331199288 7 P02545,Q8WXH0,P50402,Q00577 4 +Axial dystonia 0.8402514985188887 1.5113513844602409 0.1306989486354448 1.0 0.9639596723244256 3 Q99720 1 +Enlarged thorax 0.4727217515541192 1.5045077864615777 0.1324506699842522 1.0 0.9639596723244256 20 Q7RTS9,O75844,Q32P28 3 +Pneumothorax 0.6583443816263441 1.5042111682601451 0.1325270030132674 1.0 0.9639596723244256 6 Q8NCH0 1 +Muscle abnormality related to mitochondrial dysfunction 0.4735964672847608 1.5022827752262893 0.1330240951643935 1.0 0.9639596723244256 38 P00846,Q9Y2R0,P00403,P03886,O60313,O96000,Q9UBX3,P42704,O43676,Q86Y39 10 +Infectious encephalitis 0.6105916191141066 1.5021178603977026 0.1330666730457566 1.0 0.9639596723244256 9 Q9NZ08 1 +Congenital hepatic fibrosis 0.7484561324768046 1.5016716994600028 0.1331819162167851 1.0 0.9639596723244256 4 Q8IY17,Q8NCM8 2 +Type i diabetes mellitus 0.5750062732598058 1.501659129980358 0.1331851640262673 1.0 0.9639596723244256 11 P00403,P03886 2 +Aplasia hypoplasia involving the vertebral column 0.5408935555726394 1.5013604330203711 0.1332623619365462 1.0 0.9639596723244256 14 Q7RTS9,O95831 2 +Limb tremor 0.6572271905717608 1.4990361831064714 0.1338642455511434 1.0 0.9639596723244256 6 Q9NR77 1 +Widened cerebral subarachnoid space 0.8370415154710548 1.4987583497660777 0.1339363332619054 1.0 0.9639596723244256 3 P03886 1 +Titubation 0.5920309222532314 1.4956380255061308 0.1347480083720174 1.0 0.9639596723244256 10 Q99720,P35637,Q5JRX3 3 +Severe muscular hypotonia 0.4748847457209036 1.4946393919705356 0.1350085797166957 1.0 0.9639596723244256 33 O75381,P40855,P06753,Q9GZY8,Q8TD16,Q9H9S5,Q01105,Q9NWM8,O95831 9 +Abnormality of the odontoid process 0.6409305059339441 1.492564575464416 0.1355512019762283 1.0 0.9639596723244256 7 Q7RTS9 1 +Aplasia hypoplasia of the optic nerve 0.4744696646752189 1.4909060493281203 0.1359861629379626 1.0 0.9639596723244256 27 Q9H3S7,P07196,Q9Y5P6,O75312,O95721,P25054,Q9H9S5,P61978,Q15058,Q9H3H1,Q9UHX1 11 +Action tremor 0.4502724955473982 1.4902871399675923 0.1361487524016362 1.0 0.9639596723244256 55 P00846,Q99720,Q9Y287,P31749,Q9Y4W6,Q9NR77,P03886,Q5JRX3,P35637,O15020,Q15233,Q9H6K4,Q01082,Q8IY17 14 +Abnormal morphology of the limbic system 0.5387829293623694 1.4882797494333722 0.1366771331712912 1.0 0.9639596723244256 14 Q9UID3,Q01105 2 +Hyporeflexia of upper limbs 0.9689257176679494 1.4833444500310415 0.1379829182010954 1.0 0.9639596723244256 2 Q9NR77 1 +Patchy changes of bone mineral density 0.7439228070846473 1.4828600739527882 0.1381115911783348 1.0 0.9639596723244256 4 Q14739,Q13126 2 +Amelogenesis imperfecta 0.8322544832723573 1.4799703417914056 0.1388811617445307 1.0 0.9639596723244256 3 Q9HC07 1 +Inverted nipples 0.589005900689048 1.4793544779518948 0.1390455998337283 1.0 0.9639596723244256 10 Q2TAA5,Q15067,P61978 3 +Pericarditis 0.6946363153182402 1.4782701152917677 0.1393354932961563 1.0 0.9639596723244256 5 Q9NZ08 1 +Abnormality of the musculature of the thigh 0.622164119619882 1.4772789232595391 0.139600885361022 1.0 0.9639596723244256 8 P07196,P02545,P50402,O14979,Q8WXH0 5 +Erythema 0.4717165980742273 1.4741374429018754 0.1404445889458669 1.0 0.964142122464226 25 P22830,Q15125,P00403,Q06136,P03886,O00170,P51648 7 +Diffuse mesangial sclerosis 0.4688777504588643 1.4693076133203724 0.1417493727562004 1.0 0.9669274689223774 21 O95470,Q14C86,P00813,Q8N1F7 4 +Progressive hearing impairment 0.5355348440562675 1.4681272940846302 0.1420696488621158 1.0 0.9669274689223774 14 O60313,O60220,P03886,P00403 4 +Focal segmental glomerulosclerosis 0.4704585243474743 1.4677128909002906 0.1421822276520836 1.0 0.9669274689223774 24 P00403,Q14C86,P03886,Q8N1F7,O95470 5 +High frequency sensorineural hearing impairment 0.6916158310763335 1.465031223563216 0.1429123992029013 1.0 0.9689751899375756 5 Q9NWM8,O75844 2 +Contractures involving the joints of the feet 0.468561984366819 1.461653561189449 0.143836168955477 1.0 0.9738210392363548 22 O60313,Q8TD16,P02545,Q9H9S5,Q08J23,P50402,Q8WXH0,Q8IWS0 8 +Aplasia hypoplasia of the femur 0.5342131988969074 1.4599196859950447 0.1443121481711677 1.0 0.9741229433473896 14 Q8WVQ1,O00116,O95831,Q96HY6,Q9UHX1 5 +Abnormal motor nerve conduction velocity 0.467503863497412 1.4587257970943523 0.1446405928847214 1.0 0.9741229433473896 21 O60333,Q9NR77,P07196,Q99720 4 +Lumbar hyperlordosis 0.4669404473255509 1.4543843969229318 0.1458397633862544 1.0 0.9741229433473896 21 Q7RTS9,Q96HY6,Q9H9S5 3 +Distal upper limb amyotrophy 0.5331383841716466 1.4532417612513455 0.1461566409100445 1.0 0.9741229433473896 14 Q13501,P07196,Q9NR77,Q9BQT8,Q8TB36,P31483 6 +Cerebellar cortical atrophy 0.8254254812210922 1.4531533535863173 0.1461811802060595 1.0 0.9741229433473896 3 O75312 1 +Delayed epiphyseal ossification 0.7351530812604024 1.446426791939519 0.1480575317268357 1.0 0.979050029538038 4 Q9UG56,Q96HY6 2 +Short lingual frenulum 0.7345298577043164 1.443835688628622 0.1487852004206922 1.0 0.979050029538038 4 O75844,P21281 2 +Abnormal pupillary function 0.6453013593327341 1.443695099877039 0.1488247604150701 1.0 0.979050029538038 6 O60333,Q9NR77 2 +Abnormal corneal epithelium morphology 0.5127658405951586 1.4411257269916131 0.1495491665383335 1.0 0.979050029538038 16 Q9NZ08,O75844,P06132,Q96EK5,P51648 5 +Rimmed vacuoles 0.5124666653349884 1.4391461394535543 0.1501091217814425 1.0 0.979050029538038 16 P35609,Q9BTV4,Q13501,P22626,P02545,Q86U42,P31483,P50402,O14979,Q8WXH0 10 +Late onset 0.5810794088152776 1.4366058857496065 0.1508300102670468 1.0 0.979050029538038 10 P43304,P31751 2 +Abnormality iris morphology 0.3448842173000998 1.4320921274589409 0.1521174572043415 1.0 0.979866371697704 87 O75381,O95155,P40855,P31749,Q86YV9,Q9NR77,O60333,Q05086,P78318,Q9H9S5,Q8WXW3,Q7LGA3,Q96EK5,Q9UHX1 14 +Occipital encephalocele 0.6281228577580084 1.4309910144839293 0.1524327903888385 1.0 0.979866371697704 7 Q10713,Q9H9S5,P07942 3 +Thoracic scoliosis 0.5360278675962369 1.4233849556057692 0.154624591267376 1.0 0.9823091030670962 13 Q13724,P06753,Q9NSE4,P02545,O75844,P50542,Q9UHX1 7 +Sick sinus syndrome 0.8171975511807248 1.420824335738674 0.1553678340555944 1.0 0.9823091030670962 3 Q99996 1 +Ectrodactyly 0.4751569012492018 1.4204541050344228 0.1554755208640235 1.0 0.9823091030670962 19 P48449,Q99720,P07196,O95202,Q9NR77,Q9Y297 6 +Moderately reduced visual acuity 0.816959130728586 1.4198872949427126 0.1556404953059988 1.0 0.9823091030670962 3 O60313 1 +Abnormality of the palm 0.3571591808003198 1.4191622197526903 0.1558517276662712 1.0 0.9823091030670962 123 Q7RTS9,P40855,O75381,P31749,O95721,Q99567,Q14739,Q01082,Q8IY17,Q9UHX1,Q8NCH0,Q9Y487,P25054,P61978,P16435,P09493,Q8NCM8,Q15437,O95831,Q71SY5,P35609,Q9UID3,Q06136,P16615 24 +Skin plaque 0.6392959122802815 1.4157634062512805 0.1568447869853682 1.0 0.9823091030670962 6 P16615,P49815,Q06136 3 +Hemihypertrophy 0.9508730393607586 1.4126083353837664 0.1577709168433121 1.0 0.9823091030670962 2 P31751 1 +Abnormality of the tarsal bones 0.4647539497211185 1.4099725775851677 0.1585477802719348 1.0 0.9823091030670962 30 Q7RTS9,Q8WVQ1,Q15125,Q15058,O75844,Q99567,P16435,Q14739,Q9UHX1 9 +Abnormal palmar dermatoglyphics 0.4243637343054158 1.4084078476730575 0.1590103367795878 1.0 0.9823091030670962 63 O75381,P40855,O95202,Q8NCH0,Q9UID3,Q9Y487,P98175,P25054,Q01082,Q71SY5,Q99567,P61978,P50542,O00170,Q9UQE7,Q9Y5Y5,Q8IY17,Q9UHX1 18 +Supernumerary tooth 0.5751059580955707 1.4043176442720762 0.1602242824541022 1.0 0.9823091030670962 10 Q9UHX1 1 +Short thorax 0.607371957033626 1.4034338785874394 0.1604874963692246 1.0 0.9823091030670962 8 Q7RTS9 1 +Abnormal glomerular mesangium morphology 0.4609320521580847 1.4025181779728533 0.1607605661267188 1.0 0.9823091030670962 22 O95470,Q14C86,P00813,Q8N1F7 4 +Narrow mouth 0.3781070763393783 1.4007851256773285 0.1612783379020974 1.0 0.9823091030670962 78 P55011,O95155,Q9NX62,P21964,P42858,Q9H3S7,P31749,Q15392,Q15233,Q96PZ0,Q8NCH0,O75419,Q9Y487,P25054,P16435,Q6PGP7,Q8WVQ1,Q9UGU0,Q15555,O75844,Q7LGA3,Q8N3R9 22 +Bilateral single transverse palmar creases 0.5157711902940055 1.3982235550502782 0.1620459454411134 1.0 0.9823091030670962 15 O75381,P40855,P50542,Q9UQE7,Q8IY17 5 +Fractures of the long bones 0.7235509220007958 1.3981524872122433 0.1620672810757506 1.0 0.9823091030670962 4 Q13126 1 +Abnormal corpus striatum morphology 0.495450849074103 1.3954348745781102 0.1628847408635763 1.0 0.9823091030670962 17 P00846,O95831,Q9Y3Z3,P42858 4 +Steppage gait 0.4595302479797847 1.3866349767880135 0.165553097226774 1.0 0.9823091030670962 23 Q13501,P07196,P05023,O60333,Q9NR77,Q8TB36,P02545,P31483,Q96BR5 9 +Abnormality of the synovia 0.3343053385166149 1.386137147836176 0.1657050290741559 1.0 0.9823091030670962 91 P55011,Q7RTS9,Q8WVQ1,P06753,P31749,Q96AY3,Q9Y487,P25054,Q96A33,Q8TD16,O75718,Q9H9S5,O75844,P16435,Q8NCM8,Q9UHX1 16 +Optic disc coloboma 0.6735212668785647 1.3855543078571264 0.16588303861336 1.0 0.9823091030670962 5 P78318 1 +Abnormal mitochondria in muscle tissue 0.4589811560286446 1.382349083064433 0.166864541933573 1.0 0.9823091030670962 23 Q9Y4W6,P00403,P03886,O96000,O43676,Q86Y39 6 +Vertebral wedging 0.8070021804703743 1.3807459098947732 0.1673570999125082 1.0 0.9823091030670962 3 Q96AY3 1 +Abnormal platelet volume 0.6027444139673366 1.3802721332401875 0.1675028716700994 1.0 0.9823091030670962 8 P12814,Q6PGP7,P35579,Q14739 4 +Prominent sternum 0.8068054212806974 1.3799723120973555 0.1675951700032492 1.0 0.9823091030670962 3 Q7RTS9 1 +Retinal pigment epithelial mottling 0.8055774242233831 1.3751441304641248 0.1690867651507244 1.0 0.9823091030670962 3 P00846 1 +Preaxial hand polydactyly 0.5522745020637504 1.3736382193214505 0.1695540254951073 1.0 0.9823091030670962 11 Q2M1P5,Q8NCM8,Q9BXW9,Q9UPP1,Q9UHX1 5 +Abnormal visual field test 0.6301394031331439 1.3731031136137135 0.1697202932509849 1.0 0.9823091030670962 6 P00846 1 +Torsade de pointes 0.8046436796444592 1.3714728094621909 0.1702276140244927 1.0 0.9823091030670962 3 P0DP25 1 +Metaphyseal cupping 0.8046181172291278 1.3713723017952086 0.1702589273188635 1.0 0.9823091030670962 3 Q14739,O95831 2 +Muscle fiber atrophy 0.4561581377738673 1.3711000636467698 0.1703437651482544 1.0 0.9823091030670962 21 P35609,Q99720,P35637,P61978,P50402,Q8WXH0 6 +Decreased cervical spine flexion due to contractures of posterior cervical muscles 0.6294065964855389 1.3696854693216454 0.1707851065044217 1.0 0.9823091030670962 6 P02545,Q8WXH0,P50402 3 +Abnormal cardiac ventricular function 0.4569432764168086 1.3664347217445345 0.171802556825086 1.0 0.9823091030670962 23 O95677,P00403,P03886,Q9H9S5,O75844 5 +Scleroderma 0.6688313274163656 1.3649141299572431 0.1722800406495122 1.0 0.9823091030670962 5 Q14739,P06132 2 +Papilloma 0.5677359413776628 1.364401798771653 0.1724411420912881 1.0 0.9823091030670962 10 P16615,P31749 2 +Positional foot deformity 0.3414682638956183 1.3563095505710798 0.1750006980210356 1.0 0.9823091030670962 105 Q8NI60,Q7RTS9,Q08209,Q9NVI7,Q96A33,P21964,P50542,Q9UQE7,O95202,Q15125,Q96AY3,Q9NR77,Q8TD16,Q15392,Q96DF8,Q9NWM8,Q01082,Q9UHX1,Q8NCH0,O75845,Q9Y487,P98175,P61978,P32929,P16435,Q8NCM8,Q8WVQ1,P07196,P06753 29 +Abnormal iliac wing morphology 0.5489634197508877 1.3549118471627368 0.1754456446224415 1.0 0.9823091030670962 11 Q7RTS9 1 +Insulin resistant diabetes mellitus 0.6262120195395515 1.3547811159220255 0.1754873048864005 1.0 0.9823091030670962 6 P31751 1 +Hypoketotic hypoglycemia 0.5974136808469422 1.3535592737603306 0.1758770274881167 1.0 0.9823091030670962 8 O43772,P31751 2 +Impaired visuospatial constructive cognition 0.6112097085325052 1.349374690564553 0.1772166459622164 1.0 0.9823091030670962 7 P00403,P42858,P03886 3 +Upper limb asymmetry 0.711200371693931 1.3466926654183022 0.1780792354810869 1.0 0.9823091030670962 4 P31749 1 +Abnormal thoracic spine morphology 0.4567565904317242 1.3453043094644102 0.1785269824662301 1.0 0.9823091030670962 30 Q7RTS9,O75844,P51648,O95831,Q9UPP1,Q9UHX1 6 +Lipoma 0.6102883246521272 1.344919917516074 0.178651097407779 1.0 0.9823091030670962 7 P25054,P31749 2 +Abnormal brainstem mri signal intensity 0.454159065405636 1.3446727724154377 0.1787309311029681 1.0 0.9823091030670962 23 O95831,P03886,O96000,O43676,Q86Y39 5 +Cupped ribs 0.6236668186910129 1.3429002354718709 0.1793042801965518 1.0 0.9823091030670962 6 P00813 1 +Abnormal dermatoglyphics 0.3767962391031285 1.341233602379275 0.179844619720884 1.0 0.9823091030670962 77 P40855,P50542,O00170,Q9Y4P3,Q15056,Q9UQE7,O75381,O95202,P51812,Q96AX1,Q99567,Q9Y5Y5,Q8IY17,Q9UHX1,Q01082,Q8NCH0,Q9Y487,P98175,P25054,P61978,P21281,Q71SY5,Q9UID3 23 +Distal lower limb muscle weakness 0.4639655870395283 1.3376762881386863 0.1810019838583287 1.0 0.9823091030670962 19 P00846,Q9NR77,P07196,Q8IY17 4 +Waddling gait 0.4554170494894365 1.335551342749154 0.1816959630185124 1.0 0.9823091030670962 29 Q7RTS9,P07196,Q4J6C6,Q8TD16,Q9H9S5,P50402,Q8WXH0 7 +Large intestinal polyposis 0.5275989581749037 1.333830161370463 0.1822595238181581 1.0 0.9823091030670962 12 Q15437,P25054,P31749 3 +Aplasia hypoplasia involving the femoral head and neck 0.5780569116556384 1.3331780774233817 0.182473371789817 1.0 0.9823091030670962 9 Q8WVQ1,O95831,Q96HY6 3 +Abnormal upper motor neuron morphology 0.560752560767322 1.3265075118856324 0.184671648604688 1.0 0.9823091030670962 10 Q99720,Q8IY17,P35637 3 +Scarring alopecia of scalp 0.706227467174686 1.32595756888321 0.1848537524170814 1.0 0.9823091030670962 4 Q15125 1 +Caesarian section 0.7059536561113724 1.324815696083723 0.1852322875256549 1.0 0.9823091030670962 4 O60313,P33991 2 +Suicidal ideation 0.7907045589105933 1.316667186736765 0.1879502071331056 1.0 0.9823091030670962 3 Q01082,P42858 2 +Redundant neck skin 0.5888057048556723 1.310360243618756 0.1900739962620343 1.0 0.9823091030670962 8 Q9Y487 1 +Increased circulating antibody level 0.502015140738233 1.30964551789225 0.1903157824364099 1.0 0.9823091030670962 15 P28070 1 +Dystrophic toenail 0.6163666139233872 1.3087956188172352 0.1906035914254795 1.0 0.9823091030670962 6 O75844,Q969G3 2 +Short nail 0.7019256169140491 1.3080157673783663 0.1908679613562127 1.0 0.9823091030670962 4 Q9Y487 1 +Microcornea 0.4520701893220611 1.3072786135456274 0.1911181048365926 1.0 0.9823091030670962 33 Q13045,Q15125,Q8NCH0,O75845,Q15555,Q9H2M9,Q9H9S5,Q9ULC3,Q9P273,Q15042,Q9NWM8,O43505,Q9UQE7,Q71SY5,P49711 15 +Stuttering 0.7017197186635716 1.3071569372242973 0.1911594172865716 1.0 0.9823091030670962 4 P03886 1 +Micromelia 0.4505609476660782 1.303869401197039 0.1922781147208296 1.0 0.9823091030670962 26 Q7Z4L5,P25054,O75718,Q15392,Q14739,Q96HY6,Q9UHX1 7 +Mitochondrial myopathy 0.4513741426256155 1.3016750053106807 0.1930275074210443 1.0 0.9823091030670962 30 P00846,P00403,P56556,P03886,O60313,Q53H12,O96000,O43676,Q86Y39 9 +Abnormal blood monovalent inorganic cation concentration 0.4462550368692125 1.3008841675261578 0.1932981062138874 1.0 0.9823091030670962 20 Q13423,Q99996,P0DP25,O00170 4 +Head titubation 0.6011661383200271 1.3007757526613122 0.1933352239368833 1.0 0.9823091030670962 7 Q99720,P35637 2 +Migraine 0.4477235437103879 1.2997303645152674 0.1936933994755423 1.0 0.9823091030670962 22 O60313,O00429,Q9NZ08,P03886 4 +Abnormal femoral head morphology 0.44665560964595 1.297421012481286 0.1944863665098237 1.0 0.9823091030670962 21 Q7RTS9,Q7LGA3 2 +Abnormality of the musculature of the upper arm 0.6003560115823633 1.2968522121627957 0.1946820417602439 1.0 0.9823091030670962 7 P02545,Q8WXH0,P50402,O14979 4 +Proximal upper limb amyotrophy 0.6003560115823633 1.2968522121627957 0.1946820417602439 1.0 0.9823091030670962 7 P02545,Q8WXH0,P50402,O14979 4 +Aplasia hypoplasia involving the metacarpal bones 0.4496415392348453 1.296562683551752 0.1947816990969173 1.0 0.9823091030670962 26 Q7RTS9,Q8WVQ1,Q9NX62,Q32P28,P16435,Q9BXW9,Q14739 7 +Retinal coloboma 0.5708496695254581 1.2955647753244783 0.1951254713542958 1.0 0.9823091030670962 9 Q9Y2B2,O14936,Q9H2M9,Q10713,Q9UHX1 5 +Microretrognathia 0.4582034062917303 1.2949323260241383 0.1953435758561996 1.0 0.9823091030670962 19 Q8WVQ1,Q15125,Q8NCH0,Q2M1P5,Q9UHX1 5 +Hyperventilation 0.5996927973235303 1.2936398391887058 0.195789854662755 1.0 0.9823091030670962 7 P03886 1 +Dyslexia 0.5852209506111562 1.2923498576137142 0.1962360130731617 1.0 0.9823091030670962 8 P25054,Q01082,Q9H6K4 3 +Brachydactyly 0.3622446182123373 1.2923148286128645 0.1962481387289254 1.0 0.9823091030670962 80 P48449,Q7RTS9,O95155,Q08209,Q9NX62,Q2M1P5,Q9UQE7,P31749,Q14739,Q8N0X7,Q8IY17,Q9UHX1,Q13555,Q08J23,Q13868,P16435,Q8NCM8,O60826,Q15437,O95831,P21281,Q7Z4L5,Q13045,Q8WVQ1,Q06136 25 +Ventricular escape rhythm 0.6522358600577243 1.2917806069975193 0.1964331331680147 1.0 0.9823091030670962 5 P02545,Q8WXH0,P50402 3 +Sensory neuropathy 0.4496009340042982 1.2898114184157072 0.1971161424375378 1.0 0.9823091030670962 35 P00846,Q9H0B6,Q15067,P00403,P03886,O60313,O95831 7 +Hypokalemia 0.5689444001034007 1.2856128113124088 0.1985782233648594 1.0 0.9823091030670962 9 Q99996,P0DP25,O00170 3 +Morphological abnormality of the corticospinal tract 0.4978646957025793 1.282849862728512 0.1995446810405097 1.0 0.9823091030670962 15 Q13045,O75298,Q13501,P00846,Q14203,P35637,Q9Y4P3 7 +Atrophy degeneration involving the spinal cord 0.583090654998893 1.281641923211 0.1999682865967922 1.0 0.9823091030670962 8 P07196 1 +Prominent superficial blood vessels 0.5184089577412782 1.279336945925189 0.2007784275865964 1.0 0.9823091030670962 12 Q9Y487 1 +Limited elbow movement 0.4472564337491022 1.2791956225921592 0.2008281769636535 1.0 0.9823091030670962 38 Q7RTS9,Q96AY3,Q7LGA3,P50402,P16435,Q8WXH0,Q9H6K4 7 +Caudate atrophy 0.7806692055826056 1.277225238156764 0.2015227391819019 1.0 0.9823091030670962 3 P42858 1 +Optic disc pallor 0.4313948003832721 1.276256030370541 0.2018650278264451 1.0 0.9823091030670962 53 Q9H0B6,Q9Y287,Q9Y4W6,P03886,Q8WWV3,O60313,Q10713,Q86Y39,P00846,O00429,Q13277,P56556,O43676,Q9H6K4,Q96S66,O96000,O95831,Q6P4Q7,Q9GZY8,Q9UG56 20 +Impaired pain sensation 0.4670511723326562 1.2739314579779042 0.2026877085177707 1.0 0.9823091030670962 18 Q9NR77,O95831,P07196 3 +Conjunctival hamartoma 0.7798193794214066 1.2738863145359214 0.2027037092061006 1.0 0.9823091030670962 3 P31749 1 +Bone cyst 0.7798193794214066 1.2738863145359214 0.2027037092061006 1.0 0.9823091030670962 3 P31749 1 +Postaxial polydactyly 0.4450675528720924 1.27347265109936 0.2028503713539056 1.0 0.9823091030670962 23 Q7Z4L5,Q15125,Q14739,O75845,P98175,P61978,Q8NCM8,Q10713,Q9BRT2 9 +Head tremor 0.4959351187092686 1.27038286472355 0.2039482839498019 1.0 0.9823091030670962 15 Q9Y4W6,Q99720,P07196,P35637 4 +Melanocytic nevus 0.5167748245273531 1.2696340566165691 0.204215012284751 1.0 0.9823091030670962 12 Q96AY3,Q01082,P31749 3 +Abnormality of neutrophil morphology 0.6470942324032771 1.2690999821817472 0.2044054066561518 1.0 0.9823091030670962 5 P35579 1 +Abnormality of the intrahepatic bile duct 0.6922020322953986 1.2674523336170187 0.2049935971990839 1.0 0.9823091030670962 4 Q10713,P50542 2 +Loss of subcutaneous adipose tissue in limbs 0.6920343500147976 1.266752777748774 0.2052437019605966 1.0 0.9823091030670962 4 P02545,O75844,Q03252 3 +Overtubulated long bones 0.7779751332149307 1.2666411491251215 0.2052836318659388 1.0 0.9823091030670962 3 O75844,P21281 2 +Aplasia involving bones of the extremities 0.7779751332149184 1.266641149125072 0.2052836318659565 1.0 0.9823091030670962 3 Q9BXW9,Q8NCM8 2 +Sinus bradycardia 0.7779751332149166 1.2666411491250658 0.2052836318659587 1.0 0.9823091030670962 3 Q99996,P0DP25 2 +Loss of eyelashes 0.777975133214913 1.2666411491250509 0.2052836318659641 1.0 0.9823091030670962 3 O75844,P06132 2 +Large placenta 0.7779751332149095 1.2666411491250384 0.2052836318659685 1.0 0.9823091030670962 3 Q6PGP7,O75844 2 +Congenital muscular dystrophy 0.7779751332149075 1.2666411491250298 0.2052836318659716 1.0 0.9823091030670962 3 Q9H9S5,Q9Y5P6 2 +Recurrent pancreatitis 0.7777570165874718 1.2657843472468862 0.2055903005670027 1.0 0.9823091030670962 3 P03886 1 +Limb girdle muscle atrophy 0.5100862478131327 1.26572657824677 0.205610989367257 1.0 0.9823091030670962 13 Q8WXH0,Q9H9S5,P50402,P06753 4 +Adenocarcinoma of the small intestine 0.7776791000592104 1.2654782808744367 0.2056999292799886 1.0 0.9823091030670962 3 P25054,P78549 2 +Duodenal adenocarcinoma 0.7776791000592104 1.2654782808744367 0.2056999292799886 1.0 0.9823091030670962 3 P25054,P78549 2 +Abnormal response to endocrine stimulation test 0.7773839963448248 1.264319093722348 0.2061155190499843 1.0 0.9823091030670962 3 Q13423 1 +Temporal optic disc pallor 0.9126960639242382 1.2634341693334514 0.2064331908587893 1.0 0.9823091030670962 2 O60313 1 +Morning glory anomaly 0.9126960639242382 1.2634341693334514 0.2064331908587893 1.0 0.9823091030670962 2 O60313 1 +Duplication of the distal phalanx of hand 0.7759207703683406 1.258571902522576 0.2081850010556554 1.0 0.9823091030670962 3 Q8WVQ1 1 +Upper airway obstruction 0.6437801053424574 1.2544773990891682 0.2096685355328724 1.0 0.9823091030670962 5 O75844,Q96HY6 2 +Concentric hypertrophic cardiomyopathy 0.7742342679443064 1.2519487336787565 0.2105885452584421 1.0 0.9823091030670962 3 P03886 1 +Proximal muscle weakness in upper limbs 0.5077855514847455 1.251691088018569 0.2106824487280092 1.0 0.9823091030670962 13 P07196,Q9Y5P6,P02545,P50402,P50570,Q8WXH0 6 +Cupped ear 0.4928189610669778 1.2502377540714409 0.2112127091116136 1.0 0.9823091030670962 15 Q15392 1 +Nephropathy 0.4520212359102405 1.2489962569297766 0.2116664428995256 1.0 0.9823091030670962 19 Q7Z4L5,P00403,P03886,P35579,Q8NCM8 5 +Primary adrenal insufficiency 0.4741429838761517 1.248722754030266 0.2117664954787641 1.0 0.9823091030670962 17 O75381,Q13423,P40855,P31749 4 +Brittle hair 0.5002548777043339 1.2477583529514211 0.2121195645454996 1.0 0.9823091030670962 14 Q9Y487,O75844 2 +Tinnitus 0.500016433035461 1.246261608979002 0.2126683673000016 1.0 0.9823091030670962 14 Q9NR77,O95831,Q9NR28,P31749 4 +Flat face 0.443489756086336 1.2442585962466577 0.2134044040651392 1.0 0.9823091030670962 27 O75381,P40855,Q15125,Q9NX62,Q9Y487,Q15555,Q13555,Q03164,P50542,Q9UQE7 10 +Thick hair 0.602372083802903 1.2433263417030849 0.213747601092844 1.0 0.9823091030670962 6 Q9Y487,Q9UQE7 2 +Profound global developmental delay 0.4913494315560519 1.2407330093785292 0.2147043958288055 1.0 0.9823091030670962 15 P55011,O75381,P40855,Q9H3S7,Q9GZY8,O60313,P50542 7 +Color vision defect 0.4824628864601087 1.2396009364380398 0.215123034131401 1.0 0.9823091030670962 16 O43464,O60220,O00429,Q6P4Q7,Q8WWV3,O60313,Q9H6K4 7 +Cystic hygroma 0.5746750686138292 1.2393098721382814 0.2152307641213675 1.0 0.9823091030670962 8 Q99567,P61978 2 +Decreased number of large peripheral myelinated nerve fibers 0.6402594746585365 1.2389417481944982 0.2153670714286319 1.0 0.9823091030670962 5 Q8TB36,P07196 2 +Limb girdle muscular dystrophy 0.5745844334731878 1.2388537252418206 0.2153996733900531 1.0 0.9823091030670962 8 P02545,Q8WXH0,P50402,O14979 4 +Capillary malformation 0.4988149169699309 1.238718473688944 0.2154497748198647 1.0 0.9823091030670962 14 Q9Y4P3,Q9UQE7,Q71SY5,Q9UHX1 4 +Central heterochromia 0.9061852619118088 1.2380944108280472 0.215681056069267 1.0 0.9823091030670962 2 P31749 1 +Abnormally large globe 0.5598279581104995 1.2379518524619288 0.2157339140925531 1.0 0.9823091030670962 9 Q9H9S5,P31749 2 +Generalized hyperkeratosis 0.6009185364688974 1.2365213677258926 0.2162648281299493 1.0 0.9823091030670962 6 Q15437,O75844,P31749 3 +Foot dorsiflexor weakness 0.4429569962019254 1.236372872298778 0.2163199949712366 1.0 0.9823091030670962 36 P35609,Q99720,Q13501,P07196,P06753,P05023,O60333,Q9NR77,Q9BQT8,Q8TB36,P02545,P31483,Q96BR5,P46976,Q14739 15 +Abnormality of fundus pigmentation 0.5996006184741257 1.230350785665531 0.2185657741869495 1.0 0.9823091030670962 6 P38435,P49815,P25054,Q2M1P5 4 +Short umbilical cord 0.7672881812259486 1.224683294922684 0.2206945705953751 1.0 0.9823091030670962 3 O75844 1 +Small placenta 0.7672881812259486 1.224683294922684 0.2206945705953751 1.0 0.9823091030670962 3 O75844 1 +Chromosomal breakage induced by crosslinking agents 0.7666047116209361 1.2220017438096495 0.2217069675452392 1.0 0.9854113118566072 3 P13073 1 +Psychotic mentation 0.636151092799694 1.2208111887432505 0.2221575164907272 1.0 0.986472556543191 5 P00403,P03886 2 +Atrophy degeneration involving the corticospinal tracts 0.5025502475148667 1.2197288642527846 0.2225676757475911 1.0 0.986965775788712 13 P00846,O75298,Q13501,Q14203,P35637,Q9Y4P3 6 +Abnormality of skeletal muscle fiber size 0.4480428254151462 1.2194001217512382 0.2226923637513818 1.0 0.986965775788712 19 P35609,Q13501,P06753,O60313,O95831,Q9BPX6 6 +Impaired vibratory sensation 0.4410164942797555 1.2175242272208595 0.2234048243358695 1.0 0.9885103484297808 30 P00846,Q9NR77,P07196 3 +Upper limb spasticity 0.5838632433421691 1.2168920737370714 0.2236452817576204 1.0 0.9885103484297808 7 Q99720,P35637 2 +Arthropathy 0.6351882744387383 1.216562155609466 0.2237708489156589 1.0 0.9885103484297808 5 P22413,Q9Y3Z3,O15269 3 +Ankylosis 0.5960430594307937 1.2136917680420654 0.2248654490317987 1.0 0.9885438869802672 6 O75844,P16435 2 +Dolichocephaly 0.4399247807611113 1.2134483169415555 0.2249584629023364 1.0 0.9885438869802672 37 O75381,Q7RTS9,P40855,O95202,P31749,Q4J6C6,O95721,Q03164,P61978,P50542,Q9BXW9,Q9Y5Y5,Q01082 13 +Anarthria 0.5954152207014265 1.2107514952658365 0.2259906599854362 1.0 0.9887036795844708 6 Q99720 1 +Abnormal pelvis bone morphology 0.8990825688073413 1.2104983569636387 0.2260877208528777 1.0 0.9887036795844708 2 Q7RTS9 1 +Hereditary nonpolyposis colorectal carcinoma 0.5541397195760562 1.2081849614890616 0.2269761249935253 1.0 0.9890611702035772 9 P31749 1 +Abnormality of the subungual region 0.8981947321692814 1.2070526330246754 0.2274118749008224 1.0 0.9890611702035772 2 P16615 1 +Abnormal circulating carbohydrate concentration 0.437448352191701 1.2039584928160552 0.2286056218587304 1.0 0.991971707328179 40 Q70HW3,Q9BWD1,P22695,O95831,P03886,Q5JRX3,O96000,O43676,Q86Y39 9 +Amyotrophic lateral sclerosis 0.4675236239891295 1.2029858874231445 0.2289817818086383 1.0 0.9921833857345466 17 Q99720,Q13501,Q92804,Q15165,Q14203,Q68CQ7,P35637,P31483 8 +Bruxism 0.5805803670312479 1.2009625413149787 0.2297657321093069 1.0 0.993771108045758 7 P61978,P42858 2 +Bifid tongue 0.6754360439620839 1.1975214948676929 0.2311033546027532 1.0 0.9945380400296496 4 P61978 1 +Pancreatic islet cell hyperplasia 0.7603436768408163 1.1974493384949585 0.2311314627253056 1.0 0.9945380400296496 3 P16930 1 +Hamartomatous polyposis 0.674430632926367 1.193329950410626 0.2327401771703945 1.0 0.9955038983100988 4 P31749 1 +Skin nodule 0.4359565693693151 1.191833941144085 0.2333263643693826 1.0 0.9958095544341382 25 Q92990,P31749,O60333,Q9NZ08,P25054,P35637,P16615,P49815 8 +Cone shaped epiphysis 0.502839264161332 1.1867620608265097 0.2353214876518254 1.0 0.9986906663932708 12 Q7Z4L5,Q7RTS9,O95831,Q8NCM8 4 +Abnormal z disc morphology 0.7573662620323502 1.1857821965582929 0.2357083240818482 1.0 0.9986906663932708 3 P35609 1 +Abnormal sarcomere morphology 0.7573662620323502 1.1857821965582929 0.2357083240818482 1.0 0.9986906663932708 3 P35609 1 +Abnormality of the 1st metacarpal 0.5496690524967496 1.184778715479064 0.2361049502114416 1.0 0.9986906663932708 9 Q8WVQ1,Q15233,Q9BXW9 3 +Abnormal sweat gland morphology 0.7566607460035578 1.1830184992287829 0.236801815900048 1.0 0.9986906663932708 3 P02545,O75844 2 +Oculogyric crisis 0.5183955864400628 1.181348217149414 0.237464420046918 1.0 0.9986906663932708 11 O00429,Q01105 2 +Multiple joint contractures 0.4306648282003417 1.1801221393502177 0.2379516403866257 1.0 0.9986906663932708 20 O75844,Q9H9S5,Q99567,Q9H0B6 4 +Difficulty running 0.4894793419486041 1.1800561934038725 0.2379778660602114 1.0 0.9986906663932708 14 Q8TD16,Q9H9S5,P07196,Q9BPX6 4 +Abnormality of the shoulder girdle musculature 0.4359709260290517 1.1775251020065696 0.2389859844851778 1.0 0.999278918969442 36 Q13501,P07196,P06753,Q9Y5P6,O00429,Q9Y487,O60313,Q8TD16,P02545,P07602,Q9H9S5,P46976,P50402,O14979,Q8WXH0 15 +Reduced forced vital capacity 0.6701577251964737 1.1755205172695986 0.2397865336558049 1.0 0.999783375768967 4 Q9H9S5,P06753 2 +Functional motor deficit 0.3567145522882918 1.1744132547136463 0.2402295387005686 1.0 0.999783375768967 151 Q8NI60,Q7RTS9,Q9H0B6,P03886,P42858,Q9BPX6,P00846,P31749,O00429,Q9NR77,Q8TD16,Q9NWM8,Q9H2D1,Q9Y3Z3,P00403,Q05086,P61978,Q71SY5,Q99720,O75298,Q9Y2R0,P07196,P06753,Q15067,Q9GZY8,P35637,Q9H9S5 27 +Hammertoe 0.430229243186749 1.169610925167868 0.2421575787318914 1.0 1.0 21 Q99720,P07196,O60333,Q9NR77,Q96BR5 5 +Talipes equinovarus 0.3380771195808402 1.169479943794004 0.242210317220062 1.0 1.0 84 Q8NI60,Q7RTS9,Q96A33,P21964,Q15125,Q96AY3,Q9NR77,Q8TD16,Q15392,Q9NWM8,Q01082,Q8NCH0,O75845,Q9Y487,P98175,P61978,P16435,Q8NCM8,Q8WVQ1,P06753 20 +Flattened epiphysis 0.6685319458425135 1.1687463375516058 0.2425058466181777 1.0 1.0 4 O95831 1 +Follicular thyroid carcinoma 0.668498903937587 1.1686086738536563 0.2425613319575834 1.0 1.0 4 P31749 1 +Chorioretinal hypopigmentation 0.7525162818235744 1.1667909894839232 0.243294786699854 1.0 1.0 3 Q96AX1,P49815 2 +Focal t2 hyperintense brainstem lesion 0.4285212686515388 1.1634907576157678 0.2446304458442074 1.0 1.0 20 O43676,Q86Y39,O96000,P03886 4 +Aplasia hypoplasia of the ribs 0.4308539601833419 1.161837290839451 0.2453015633956643 1.0 1.0 23 Q7Z4L5,O95155,Q03164,Q14739,Q96HY6,Q9UHX1 6 +Abnormal brain lactate level by mrs 0.5305040677791821 1.1617834895969164 0.2453234221941751 1.0 1.0 10 O00429,P03886 2 +Hypothermia 0.5147499070020702 1.1605920861275605 0.245807825291501 1.0 1.0 11 P00846,P03886 2 +Thoracic hypoplasia 0.4340902742825964 1.1586261953835126 0.2466085864709786 1.0 1.0 33 Q7Z4L5,P06753,Q96A33,O75718,P16435,Q8NCM8,Q14739,Q96HY6,Q9UHX1 9 +Insulin resistance 0.470017509830761 1.1564082632609685 0.2475142032300912 1.0 1.0 16 O75844,P43304,P31751 3 +Dyschromatopsia 0.5707831396031653 1.1534137684184205 0.2487405928629609 1.0 1.0 7 O00429,O60313,Q9H6K4 3 +Distal amyotrophy 0.3997918733537829 1.1520860074058192 0.249285732443482 1.0 1.0 63 Q9H0B6,Q9Y4W6,Q9NVI7,P31483,P50570,O60333,Q9NR77,Q9BQT8,Q8TB36,Q8TD16,Q8N0X7,Q8IY17,Q13501,Q14203,Q71SY5,P35609,Q99720,P07196,P06753,Q7Z406,P35637,P02545,Q96BR5 23 +Abnormal rib cage morphology 0.3326704996273636 1.1476565446399196 0.2511103770646476 1.0 1.0 85 Q7Z4L5,O95155,Q7RTS9,P31749,Q08209,P25054,Q32P28,Q03164,O75844,O75718,P16435,Q8NCM8,Q14739,O95831,P00813,Q96HY6,Q9UHX1 17 +Abnormal caudate nucleus morphology 0.5122987745587226 1.1466337123369594 0.2515330372509035 1.0 1.0 11 P00846,P42858 2 +Photophobia 0.4303362788452792 1.1424503303799305 0.2532668808090914 1.0 1.0 40 P48449,Q96S66,O60220,Q9Y4W6,Q9BV73,Q86YV9,Q9NZ08,Q6P4Q7,Q15555,Q8WWV3,P51648,Q8IY17 12 +Reduced vital capacity 0.7458674297142676 1.1407870833564109 0.2539585370395869 1.0 1.0 3 P35609 1 +Underdeveloped supraorbital ridges 0.483147074676728 1.140225871436528 0.254192211681068 1.0 1.0 14 O75381,P40855,P98175,Q08J23,P16435,P50542,Q6PGP7 7 +Neck flexor weakness 0.6614356673431836 1.1391943238664046 0.2546221125119086 1.0 1.0 4 Q99720 1 +High myopia 0.5409453825139419 1.1390900763541385 0.2546655861254456 1.0 1.0 9 Q9Y487 1 +Incisor macrodontia 0.4372161824295442 1.138761494458179 0.2548026461254218 1.0 1.0 19 P55011,Q9UGU0,Q9H3S7,Q96PZ0,Q00577,Q7LGA3,P42858,Q8N3R9 8 +Abnormality of fontanelles 0.4153736582207542 1.1379639041515328 0.2551355550334304 1.0 1.0 54 P40855,Q9BT22,Q2M1P5,P50542,Q9UQE7,O75381,Q15125,P51812,Q32P28,O15111,Q9Y5Y5,Q01082,Q8NCH0,Q9Y487,P98175,O75419,Q08J23,P16435,P02545,O75718,O75844,Q9H0W8 22 +Motor axonal neuropathy 0.4671401226174431 1.1371564579372535 0.2554728856534642 1.0 1.0 16 O60313,O95831,Q9H0B6 3 +Epiphyseal stippling 0.4752241012258026 1.1362908431822003 0.2558348617875068 1.0 1.0 15 O75381,P40855,Q15125,O00116,P50542,Q14739,P38435 7 +Intrinsic hand muscle atrophy 0.616969011273926 1.1361861262735518 0.2558786756517006 1.0 1.0 5 Q13501,Q9NR77 2 +Neoplasm of the small intestine 0.5784837777357555 1.13145400732054 0.2578640510735377 1.0 1.0 6 P02545,P25054,P78549 3 +Raynaud phenomenon 0.5779276853782993 1.12885024537108 0.2589610126056541 1.0 1.0 6 Q14739,O75844,Q9Y3Z3 3 +Intellectual disability progressive 0.4870960960885468 1.1252390390205094 0.2604877543214892 1.0 1.0 13 Q15067,O95831,Q05086 3 +Multiple prenatal fractures 0.5770869970196407 1.1249141204289892 0.2606254277825082 1.0 1.0 6 O75718,Q32P28,P06753 3 +Tetraplegia 0.4864902500071492 1.1215321819407058 0.2620614008435069 1.0 1.0 13 Q13423 1 +Ambiguous genitalia male 0.7402260833031197 1.1187559471210162 0.263244270022537 1.0 1.0 3 Q15392 1 +Tremor by anatomical site 0.4282381790766855 1.1157621495518668 0.2645239595873963 1.0 1.0 29 Q99720,P07196,Q9Y4W6,Q9NR77,Q05086,P35637 6 +Abnormal incisor morphology 0.4222801104020364 1.115048014246187 0.264829846923754 1.0 1.0 20 P55011,Q9UGU0,Q9H3S7,Q96PZ0,Q00577,Q7LGA3,P42858,Q8N3R9 8 +Abnormality of upper limb joint 0.3403538250102386 1.114070375865598 0.265248996317637 1.0 1.0 130 O95155,Q7RTS9,Q03164,Q8WXH0,Q15125,P31749,Q96AY3,Q9NR77,Q15392,Q99567,Q9H6K4,P25054,P16435,O95831,Q71SY5,P07196,P06753,O75844,Q7LGA3,P50402 20 +Facial asymmetry 0.4286277390630887 1.1133717850892046 0.2655487875855864 1.0 1.0 33 Q8NCH0,Q03164,Q01105,Q9UHX1 4 +Abnormal protein o linked glycosylation 0.7386027235050077 1.1124223365229085 0.2659566052126059 1.0 1.0 3 Q8N511,Q10471 2 +Xerostomia 0.4630977112583647 1.1101044266778326 0.2669540299333919 1.0 1.0 16 Q13501,Q92804,Q15165,Q68CQ7,P35637,Q14739 6 +Tapered finger 0.4271902354825362 1.108009615848484 0.2678576630948877 1.0 1.0 38 Q9UGU0,Q8NCH0,Q15555,Q2M1P5,Q06136,Q03164,Q03252,O00170,Q96EK5,Q8IWS0 10 +Abnormal renal cortex morphology 0.4073063365392941 1.1074181366951692 0.2681131880493128 1.0 1.0 57 P00846,O60333,Q9NZ08,P00403,Q14C86,P03886,Q8N1F7,O95470,Q6PGP7,P00813 10 +Retinal atrophy 0.4274082585042944 1.1067130379989971 0.2684180165520229 1.0 1.0 30 P55011,Q9H3S7,Q96PZ0,Q9H9S5,Q7LGA3,P42858,Q10713,P51648,Q8N3R9 9 +Lateral clavicle hook 0.7369344970423901 1.1059166935249862 0.2687625786090353 1.0 1.0 3 Q8NCM8 1 +Thickened nuchal skin fold 0.4704974372855078 1.105646694186159 0.2688794707433946 1.0 1.0 15 O75381,Q13501,P40855,Q15125,P61978,P50542,Q9Y5Y5 7 +Intestinal malrotation 0.4271141267738527 1.1025610788391176 0.2702178202453345 1.0 1.0 31 P55011,O75312,Q8NCH0,O60826,Q15392,P21964,Q8NCM8,Q14739,Q9UQE7 9 +Myoclonic spasms 0.5720985931714573 1.10156385146492 0.2706513310065892 1.0 1.0 6 P00846 1 +Abnormal sternum morphology 0.3296463166888216 1.1004652885703368 0.2711294455151622 1.0 1.0 114 P55011,Q7RTS9,Q9NVI7,Q2M1P5,Q96A33,Q03164,Q8WXH0,Q9UQE7,P31749,Q96AY3,Q14739,P55795,Q9UHX1,Q8NCH0,Q9Y487,P98175,Q08J23,P61978,Q8NCM8,Q15437,O95831,Q71SY5,Q7Z4L5,P06753,Q15555,P78318,O75718,Q7LGA3,P50402 29 +Giant platelets 0.8700799052974262 1.0984686756218385 0.2719998885851309 1.0 1.0 2 P35579 1 +Abnormality of the upper arm 0.422691132341574 1.0976293313022265 0.2723663795474282 1.0 1.0 23 Q7RTS9,O00116,P50402,P16435,Q8WXH0 5 +Thickened skin 0.3243172568991332 1.0962982085254658 0.2729482931364595 1.0 1.0 106 P48449,P40855,P31751,Q15800,P06132,O95470,Q8WXH0,P51648,O75381,P28070,Q15125,P31749,O95721,Q9NWM8,Q14739,P00813,P09493,Q15437,P35609,Q15555,Q06136,P16615,O75844,P50402 24 +Lymphopenia 0.4232369816356545 1.0961209237743 0.2730258590556251 1.0 1.0 24 O95470,P28070,P00813 3 +Focal emotional seizure 0.5327053608722363 1.095933437068631 0.2731079049515705 1.0 1.0 9 Q01105 1 +Abnormality of the wrist 0.4263041462242909 1.094743024475406 0.2736292337752997 1.0 1.0 35 Q7RTS9,Q15125,P31749,P25054,O75844,O95831,Q9H6K4 7 +Abnormality of epiphysis morphology 0.3897326027164141 1.0936663980124084 0.2741013166101782 1.0 1.0 65 Q7RTS9,P40855,Q2M1P5,P50542,Q5JRA6,O75381,O95202,Q15125,Q9HC07,Q14739,O75419,P16435,Q8NCM8,O95831,P38435,Q96HY6,Q7Z4L5,Q8WVQ1,O00116,Q7LGA3,Q9UG56 21 +Fetal ultrasound soft marker 0.4212108068847354 1.092385731665636 0.274663591847609 1.0 1.0 22 O75381,Q13501,P40855,Q15125,P61978,P50542,P16435,O60826,Q9Y5Y5 9 +Decreased muscle mass 0.4511806986405071 1.089902382578331 0.2757561469757097 1.0 1.0 17 Q8NCH0,Q9Y487 2 +Kyphoscoliosis 0.4017961322368836 1.0884779887030145 0.2763841485569855 1.0 1.0 59 Q5MNZ6,P31749,Q96AY3,Q8NCH0,Q9NR77,Q9HC07,Q9Y487,Q9H9S5,Q9NWM8 9 +Dilated cardiomyopathy 0.4215941434273051 1.0883366541811856 0.276446514726586 1.0 1.0 44 P00846,O95155,P35609,O95677,P06753,P00403,P03886,Q9H9S5,P09493,Q8WXH0 10 +Internally nucleated skeletal muscle fibers 0.8671204498372309 1.0871088564576852 0.2769887042624639 1.0 1.0 2 P35609 1 +Scapular winging 0.4235412083564118 1.0843754762418174 0.2781983526090759 1.0 1.0 27 P07196,P06753,O00429,Q9Y487,O60313,Q8TD16,P50402,Q8WXH0 8 +Abnormality of bladder morphology 0.5161960291680061 1.0837168513596305 0.2784903616481573 1.0 1.0 10 Q9NWM8,Q9Y4P3,P16435 3 +Venous malformation 0.8662326131991727 1.0837039144329574 0.2784960994736543 1.0 1.0 2 P31749 1 +Hand muscle weakness 0.4852909503083122 1.0822111671865495 0.2791587075221171 1.0 1.0 12 Q13501,P07196,Q9NR77,Q8TD16,P31483 5 +Anisopoikilocytosis 0.7302438871629906 1.0798579188566777 0.2802054547592032 1.0 1.0 3 O75845 1 +Gingival fibromatosis 0.6041551115633659 1.079741799329197 0.2802571747744924 1.0 1.0 5 Q15392 1 +Toxemia of pregnancy 0.5666884271765781 1.0762535177886356 0.2818138907731451 1.0 1.0 6 Q14739,O43772,Q01082 3 +Hypoparathyroidism 0.4659391713987832 1.076092479459076 0.281885898749421 1.0 1.0 15 P21964,P00403,Q96DF8,P03886 4 +Fetal akinesia sequence 0.6029343636075226 1.0743707020277944 0.2826565682407069 1.0 1.0 5 Q99567 1 +Breech presentation 0.5285631660008944 1.0742456010243515 0.2827126191898816 1.0 1.0 9 Q9H3S7,P06753,O60313,Q969X5,O75718 5 +Abnormal foot bone ossification 0.6452860150820043 1.0720758853392236 0.2836859491140542 1.0 1.0 4 Q14739,Q15125 2 +Positive romberg sign 0.5413032772437992 1.0712500054855945 0.2840570326585496 1.0 1.0 8 P07196 1 +J shaped sella turcica 0.6440627776132597 1.0670019564253397 0.2859709524888756 1.0 1.0 4 Q96AX1,O75431,P08236 3 +Ankle clonus 0.4774236342892174 1.0660547253245152 0.2863989042149293 1.0 1.0 13 O75298,O60220,Q8N0X7,P42858 4 +Synostosis of metacarpals metatarsals 0.7266863747200802 1.0660251130424168 0.2864122897855008 1.0 1.0 3 P16435 1 +Abnormal cardiac exercise stress test 0.8614974844628601 1.065568528310267 0.2866187322006936 1.0 1.0 2 P0DP25 1 +Abnormal pelvis bone ossification 0.8612015389168405 1.0644364606807772 0.2871310240589184 1.0 1.0 2 Q14739 1 +Lethal skeletal dysplasia 0.8612015389168405 1.0644364606807772 0.2871310240589184 1.0 1.0 2 Q14739 1 +Abnormal thalamic size 0.7261356280760592 1.0638851549567716 0.2873807287652039 1.0 1.0 3 Q9H9S5 1 +Delayed menarche 0.5639939458850449 1.063655037455414 0.2874849999751592 1.0 1.0 6 O75844 1 +Prominent ear helix 0.6427203169438054 1.0614353849350011 0.2884920831149813 1.0 1.0 4 P02545,O75844 2 +Adenomatous colonic polyposis 0.5998096370044462 1.060628482885064 0.2888587730230458 1.0 1.0 5 P25054 1 +Osteolysis involving bones of the feet 0.5992992576102725 1.0583847656752623 0.2898800619554262 1.0 1.0 5 P02545,O75844 2 +Foot acroosteolysis 0.5992992576102725 1.0583847656752623 0.2898800619554262 1.0 1.0 5 P02545,O75844 2 +Meningocele 0.4812222995697296 1.0579650030490189 0.2900713979432467 1.0 1.0 12 Q10713,O75845,Q9H9S5,P21964 4 +Abnormality of the radioulnar joints 0.8576501923646062 1.050864912120061 0.2933206376144097 1.0 1.0 2 P16435 1 +Radioulnar dislocation 0.8576501923646062 1.050864912120061 0.2933206376144097 1.0 1.0 2 P16435 1 +Abnormal tarsal ossification 0.8576501923646062 1.050864912120061 0.2933206376144097 1.0 1.0 2 Q15125 1 +Abnormality of the calf musculature 0.4542257402628609 1.050732116375355 0.2933816411658196 1.0 1.0 16 Q9NR77 1 +Pulmonary artery dilatation 0.4539876441491093 1.049139094316078 0.2941141053379579 1.0 1.0 16 P55011,Q9H3S7,Q96PZ0,Q7LGA3,P42858,Q8N3R9 6 +Short ribs 0.4949920889861623 1.0480651349867098 0.294608598271421 1.0 1.0 11 Q7Z4L5,Q96HY6,Q14739 3 +Abnormality of facial adipose tissue 0.6392947452215394 1.0472405201232935 0.2949886612118413 1.0 1.0 4 O75844,Q03252 2 +Mental deterioration 0.3157733404055706 1.0463172959596776 0.2954145625329163 1.0 1.0 98 O60220,Q9Y287,Q08209,Q9UBB4,P03886,O60313,O43681,Q03164,P21964,Q9BQE5,P42858,Q10713,O95470,P42704,P00846,O00429,P56556,Q8IY17,O43464,Q13501,Q9NPL8,Q9Y487,P00403,P35637,P07602,Q96QK1 26 +Vasculitis 0.5360760008926259 1.0449503140919174 0.2960459338830159 1.0 1.0 8 Q9NZ08 1 +Spastic tetraparesis 0.4174390148489264 1.0448089424153029 0.2961112810674824 1.0 1.0 25 Q7RTS9 1 +Gynecomastia 0.4155801894963571 1.0416917821688427 0.2975546002280991 1.0 1.0 23 Q8NI60,P31749,P31751,O00170,Q15437,Q01082,Q8IY17 7 +Flat forehead 0.5950773308997804 1.039834719394443 0.2984166956408649 1.0 1.0 5 Q8NCH0 1 +Intestinal pseudo obstruction 0.5217129967205589 1.0383992842628176 0.299084202651005 1.0 1.0 9 P00403,P03886 2 +Long toe 0.5077812093280423 1.0378271954420586 0.299350513267689 1.0 1.0 10 Q9UHX1 1 +Biliary tract neoplasm 0.6365124739951278 1.0357219397848898 0.3003318838031519 1.0 1.0 4 P07602,O43681 2 +Neoplasm of the gallbladder 0.6365124739951278 1.0357219397848898 0.3003318838031519 1.0 1.0 4 P07602,O43681 2 +Vaginal atresia 0.8511393903521765 1.0260501260401382 0.3048679571732955 1.0 1.0 2 P16435 1 +Calcific stippling 0.6329440945572995 1.0209638387572608 0.3072715715085972 1.0 1.0 4 Q15125 1 +Shuffling gait 0.4902043233161976 1.0208145010050311 0.307342332779716 1.0 1.0 11 O60220,Q14203,P02545,O75844,Q96QK1 5 +Ascending tubular aorta aneurysm 0.5905661808806897 1.020036161021514 0.3077113111945122 1.0 1.0 5 P02545,O75844 2 +Unexplained fevers 0.5544098199292351 1.0188933794739632 0.308253587122504 1.0 1.0 6 Q9HC07,Q9Y3Z3 2 +Nocturnal hypoventilation 0.7140435398956182 1.0170143022552742 0.3091466256606994 1.0 1.0 3 Q9H9S5 1 +Abnormal circulating porphyrin concentration 0.6316051966931269 1.0154310157443742 0.3099004146247459 1.0 1.0 4 P06132 1 +Central apnea 0.5417110277811996 1.0124865688064784 0.3113054654037639 1.0 1.0 7 P07602,O76024,Q10713 3 +Abnormality of the phalanges of the toes 0.4109964963634076 1.012414798337068 0.3113397656850853 1.0 1.0 22 Q8WVQ1,Q2M1P5,Q9Y2B2,O14936,P02545,O75844,Q9ULC3,Q7LGA3,Q9BXW9,P21281,Q71SY5,P49711 12 +Frequent falls 0.4147456171267097 1.0114119323866362 0.3118193124649633 1.0 1.0 41 P00846,Q7RTS9,Q9NR77 3 +Metatarsus adductus 0.448301156922583 1.011104764983188 0.3119662900085846 1.0 1.0 16 Q15392,Q08J23,Q03252,P50542 4 +Dental crowding 0.4137890433849082 1.0107389387673096 0.3121413949663523 1.0 1.0 26 O75844,Q01105,P06753,Q96A33 4 +Focal non motor seizure 0.5028098086491535 1.0107385437624024 0.3121415840728685 1.0 1.0 10 Q01105 1 +Progeroid facial appearance 0.5412760720991117 1.0103830310346686 0.3123118145294385 1.0 1.0 7 P02545,O75844,O75431,Q03252 4 +Upper limb amyotrophy 0.4394458525918375 1.0087030516704931 0.3131170678102917 1.0 1.0 17 Q13501,P07196,Q9NR77,Q9BQT8,Q8TB36,P31483 6 +Multiple lipomas 0.5406484536220695 1.0073481231482977 0.3137675115698262 1.0 1.0 7 P31749 1 +Fatigable weakness of bulbar muscles 0.447316939091515 1.0045247755140196 0.3151257354374386 1.0 1.0 16 Q13501,Q92804,Q15165,P06753,Q9Y5P6,Q68CQ7,P35637 7 +Duplication of phalanx of hallux 0.7107756068679619 1.004388023558911 0.3151916204544522 1.0 1.0 3 Q8WVQ1,Q2M1P5 2 +Abnormality of the supraorbital ridges 0.4123379328221405 1.0043201455583413 0.3152243264060812 1.0 1.0 25 O75381,P40855,P17980,P98175,P38159,Q08J23,P50542,P16435,Q6PGP7,Q8IWS0,Q9UPP1,Q9Y5Y5 12 +Decreased absent ankle reflexes 0.4611399793572738 1.001772099729471 0.3164536752213243 1.0 1.0 14 O60313,P07196,Q9H6K4 3 +Paresthesia 0.4104511642321189 1.0013674612792254 0.3166491891430421 1.0 1.0 23 P07196,Q9NR77,Q9NZ08,Q9H6K4 4 +Recurrent fever 0.4716874080268521 1.00117393880612 0.3167427236835975 1.0 1.0 12 P28070,Q9NR77,P61978 3 +Ileus 0.6281023664057124 1.0009685964621118 0.3168419908993489 1.0 1.0 4 Q01844 1 +Abnormality of pulmonary circulation 0.4149748455148931 1.0002520828613692 0.317188529893921 1.0 1.0 33 P31749,Q9NZ08,P00403,P03886,O75844,O96000 6 +Negativism 0.8431488606096506 0.9957218944547986 0.3193852890395394 1.0 1.0 2 Q9BQE5 1 +Social and occupational deterioration 0.8431488606096506 0.9957218944547986 0.3193852890395394 1.0 1.0 2 Q9BQE5 1 +Erythroderma 0.513444190425753 0.9951810010752516 0.3196482403894978 1.0 1.0 9 P00813,Q15125 2 +Scanning speech 0.7083328761905097 0.9949624973609216 0.3197545045174474 1.0 1.0 3 Q8IY17 1 +Elevated circulating long chain fatty acid concentration 0.7078152753108313 0.9929666901979928 0.3207261875751448 1.0 1.0 3 P40855,P50542 2 +Aplasia hypoplasia of the hallux 0.4092860280608449 0.9922119017778808 0.3210941678601808 1.0 1.0 23 P55011,Q9UGU0,Q9H3S7,Q96PZ0,Q7LGA3,P42858,Q8N3R9,Q9UHX1 8 +Depressed nasal tip 0.6258554061040952 0.991701447424569 0.3213431847794423 1.0 1.0 4 Q03164 1 +Macrodactyly 0.8419650784255714 0.9912414022217676 0.3215677184341818 1.0 1.0 2 P31749 1 +Schistocytosis 0.6257060908455988 0.991085915531107 0.3216436297745608 1.0 1.0 4 O75845,Q05682 2 +Ocular albinism 0.548317445086967 0.9904915111531374 0.3219339363056723 1.0 1.0 6 Q86YV9 1 +Fluctuations in consciousness 0.5244718199560169 0.9866551034101104 0.3238117468360628 1.0 1.0 8 P03886 1 +Abnormality of the metacarpal bones 0.4107676349160531 0.9861918063402488 0.324038999282604 1.0 1.0 43 Q7RTS9,Q8WVQ1,P31749,Q9NX62,Q2M1P5,Q32P28,P25054,P16435,Q9BXW9,Q14739,Q15233,Q9UQE7 12 +Limb undergrowth 0.3979957758330446 0.9844637337721552 0.3248875545181384 1.0 1.0 55 Q7Z4L5,Q7RTS9,Q15125,P25054,O00116,Q03164,Q15392,O75718,Q14739,Q96HY6,Q9UHX1 11 +Nasal speech 0.4110529599962406 0.983627752881374 0.3252985743182788 1.0 1.0 42 P55011,Q9H3S7,Q96PZ0,P06753,Q4J6C6,Q9Y487,P21964,Q96DF8,Q7LGA3,Q8N3R9,P42858,Q9UPP1,Q15233,Q9NZN8 14 +Unilateral renal agenesis 0.4073129938933566 0.983601485662802 0.3253114943829949 1.0 1.0 22 Q66GS9,Q86XL3,Q7LGA3,Q9UHX1 4 +Abnormal adipose tissue morphology 0.3913180398003245 0.9828051693246158 0.3257033371957711 1.0 1.0 59 P35609,P28070,Q9Y3Z3,P31749,P31751,Q2TAA5,Q9Y487,P25054,O75844,P50402,P09493,Q8WXH0 12 +Hip contracture 0.4683039462894214 0.9810395050645878 0.3265732605893516 1.0 1.0 12 Q96AY3,Q8TD16,Q7LGA3 3 +Acne 0.4435197742598357 0.9791499172822634 0.3275059104058444 1.0 1.0 16 Q92890,O00192,Q9NZ08,Q9H488,P21964,O00170,P22413 7 +Hemivertebrae 0.4674894046619186 0.9761942258756712 0.3289682240855858 1.0 1.0 12 Q15125,P16435,O60826,P21281,Q9UHX1 5 +Airway obstruction 0.4255124701002725 0.9761727844584056 0.3289788475583781 1.0 1.0 18 O75844,P25054,P09601,Q96HY6 4 +Abnormality of pain sensation 0.409740121307299 0.9737409137974468 0.3301851972146479 1.0 1.0 27 Q8NCH0,Q9NR77,O95831,P07196 4 +Iris hypopigmentation 0.5217834144210494 0.9731725435448882 0.3304675543493518 1.0 1.0 8 Q86YV9,Q05086 2 +Ectropion 0.4815908436170873 0.9718409401101212 0.3311296851013625 1.0 1.0 11 P25054,P61978 2 +Hemianopia 0.4954919710294051 0.97091126141733 0.3315924697923145 1.0 1.0 10 P00403,P03886,P31749 3 +Subcutaneous nodule 0.4043670121273794 0.9680651971658518 0.3330118098126822 1.0 1.0 21 P31749,Q9NZ08,P25054,P35637,P49815 5 +Skeletal dysplasia 0.4042757476919739 0.9631440911816468 0.3354752177053406 1.0 1.0 48 Q7Z4L5,O75381,Q7RTS9,P31749,Q9HC07,P51648,O95831,Q96HY6 8 +Short femur 0.5775446457319089 0.9630446484522274 0.3355251174137612 1.0 1.0 5 Q9UHX1 1 +Abnormal circulating aromatic amino acid concentration 0.5774192160018856 0.9624969913661964 0.3358000137744117 1.0 1.0 5 P16930 1 +Panniculitis 0.5194895259705576 0.9616768798010196 0.3362119396401199 1.0 1.0 8 P28070 1 +Impaired tandem gait 0.4234817458564479 0.9616347145814282 0.3362331271830669 1.0 1.0 18 P55011,Q9H3S7,Q96PZ0,Q7LGA3,P42858,Q8N3R9 6 +Lambdoidal craniosynostosis 0.6182515465232441 0.9604045086066142 0.3368516698593775 1.0 1.0 4 P61978 1 +Limitation of movement at ankles 0.6182022428354259 0.9602019196913596 0.3369536008878913 1.0 1.0 4 Q05086 1 +Spontaneous abortion 0.698638247483709 0.957668055933202 0.3382301696007206 1.0 1.0 3 Q9NQX3,P50570 2 +Abnormal metacarpal morphology 0.4093793978811781 0.95535273886524 0.3393993455674662 1.0 1.0 32 Q7RTS9,Q8WVQ1,Q9NX62,Q2M1P5,Q32P28,P16435,Q9BXW9,Q14739,Q15233 9 +Aplasia hypoplasia affecting the fundus 0.4089510364363253 0.9538338972233162 0.3401677280882036 1.0 1.0 31 Q9H3S7,P07196,Q9Y5P6,O75312,Q86YV9,O95721,P25054,Q9H9S5,P61978,Q15058,Q9H3H1,Q9UHX1 12 +Gait imbalance 0.4024481867454638 0.9531395060069324 0.3405193919265175 1.0 1.0 21 Q9NR77,Q05086,P42858 3 +Deviation of the 2nd finger 0.5402047843872797 0.9527523100445294 0.3407155825239576 1.0 1.0 6 Q9H6K4,Q71SY5 2 +Lower limb asymmetry 0.4917238425804959 0.9504313594011212 0.3418931160020844 1.0 1.0 10 O95155,P31749 2 +Abnormality of retinal pigmentation 0.34798201682183 0.9493100352760284 0.3424629510856722 1.0 1.0 76 P00846,O75381,Q16836,P40855,Q96S66,Q7Z4L5,P31749,Q15555,Q6P4Q7,Q15067,P00403,P25054,P03886,Q9H9S5,Q8NCM8,P51648,Q8IY17 17 +Bilateral polymicrogyria 0.5046499023762929 0.9493078671001676 0.3424640534983285 1.0 1.0 9 Q01105 1 +Heat intolerance 0.5743945170330198 0.9492989677565316 0.3424685784083103 1.0 1.0 5 Q05086 1 +Knee clonus 0.8307191476768292 0.9488516152641676 0.3426960859866965 1.0 1.0 2 O75298 1 +Abnormal astrocyte morphology 0.4113551509375638 0.9461454391187868 0.3440744103179423 1.0 1.0 19 P00846,P49815,O95831,P25054 4 +Spinal canal stenosis 0.4909057990391333 0.9459882340602852 0.3441545874610696 1.0 1.0 10 O95155,P31749,O00170 3 +Shoulder girdle muscle atrophy 0.6146512967332516 0.9456234621447824 0.3443406730204921 1.0 1.0 4 Q9H9S5 1 +Bone fracture 0.5276620272672551 0.9446722092057636 0.3448262493173595 1.0 1.0 7 Q13126 1 +Abnormal erythrocyte sedimentation rate 0.5276434437848272 0.9445827112394126 0.3448719568919762 1.0 1.0 7 P28070 1 +Abnormal circulating pyruvate family amino acid concentration 0.4022782023146575 0.9442586864231036 0.3450374721733431 1.0 1.0 22 P00846,P22695,Q9P0J1,O75208,P03886,O96000 6 +Degeneration of the striatum 0.6141312322891521 0.9434904321816944 0.3454301069171721 1.0 1.0 4 P42858 1 +Cytochrome c oxidase negative muscle fibers 0.51570807147457 0.94274489089458 0.3458114058612118 1.0 1.0 8 P42704,Q9Y2R0 2 +Proximal tubulopathy 0.4050148218906179 0.9408328309923638 0.3467905334146577 1.0 1.0 26 P00403,P03886,O96000,O43676,Q86Y39 5 +Long penis 0.6942078028795742 0.940689750459522 0.3468638729907549 1.0 1.0 3 P31749 1 +Myopathy 0.3092029789281111 0.9399322577535066 0.3472523096668698 1.0 1.0 99 P00846,O95155,P35609,P07196,P31749,Q8NCH0,Q13126,O00429,P00403,P03886,O60313,Q9H9S5,P50402,P09493,Q9NWM8,Q8WXH0,O43676,Q86Y39 18 +Severe short stature 0.4041945447156788 0.9397665680362972 0.3473373110096345 1.0 1.0 25 Q8IY17,Q7RTS9,Q8WVQ1,Q96EY7,Q15392,Q96HY6 6 +Generalized dystonia 0.6938301807968628 0.939244654982724 0.3476051468505581 1.0 1.0 3 O60220 1 +Brisk reflexes 0.4011762045548515 0.9356553268890808 0.3494506784467093 1.0 1.0 22 Q8NI60,Q99720,P35637,Q5JRX3,Q01082,Q9BSJ2 6 +Absent toe 0.4047213161543432 0.9335794745686302 0.3505208571082741 1.0 1.0 27 P55011,Q9UGU0,Q9H3S7,Q96PZ0,O95202,P25054,Q7LGA3,P42858,Q8N3R9,Q9UHX1 10 +Alveolar ridge overgrowth 0.8265759100325569 0.9333190869404316 0.3506552431095604 1.0 1.0 2 Q15392 1 +Polydactyly 0.3940167552650747 0.9322110498561796 0.3512274660323333 1.0 1.0 54 O95155,Q2M1P5,P21964,Q10713,Q15125,Q8WXW3,Q14739,Q8IY17,Q9UHX1,Q00577,O75845,O75419,P98175,P61978,Q8NCM8,O60826,Q9BRT2,Q7Z4L5,Q15067,Q9BXW9,Q9UPP1 21 +Abnormal scapula morphology 0.391119709958971 0.9319545934458718 0.3513599919410288 1.0 1.0 56 Q7RTS9,P07196,P06753,O00429,Q9Y487,P46783,O60313,Q8TD16,P50402,P16435,Q14739,Q8WXH0 12 +Overlapping fingers 0.5010219529300868 0.9304194653319232 0.3521539440242591 1.0 1.0 9 Q8TD16,Q15125 2 +Hyperorality 0.5699703744572694 0.9300258298481928 0.3523577109607014 1.0 1.0 5 Q13501,Q05086 2 +Interrupted aortic arch 0.6106843523380838 0.9293673294013558 0.3526987530775827 1.0 1.0 4 Q96DF8 1 +Frontal cortical atrophy 0.4089604511340933 0.9283565469689488 0.3532226507517171 1.0 1.0 19 P55011,Q9H3S7,Q96PZ0,Q7LGA3,P42858,Q8N3R9 6 +Generalized hirsutism 0.4045699742106784 0.9279749003422628 0.3534205895653086 1.0 1.0 28 O95155,P31749,Q15555,Q06136,Q03164,Q03252 6 +Progressive visual loss 0.402661806237639 0.927633018902024 0.353597963931805 1.0 1.0 25 P00846,P31749,O00429,P03886,O60313 5 +Abnormality of the anterior fontanelle 0.4057407199631289 0.9269288477676692 0.3539634781192535 1.0 1.0 39 O75381,P40855,Q15125,P51812,Q9Y487,O75419,Q2M1P5,Q32P28,O75718,Q08J23,P50542,P16435,O15111,Q9H0W8,Q9UQE7,Q9Y5Y5 16 +Periorbital edema 0.4042555925715426 0.925448689198188 0.3547325622140009 1.0 1.0 28 P28070,Q8NFH4,Q14C86,P50542,O00170,Q8N1F7,O43707,Q9Y4P3,Q01082 9 +Saccadic smooth pursuit 0.6095613219579537 0.924771350482286 0.3550848561374251 1.0 1.0 4 Q10713 1 +Contractures of the large joints 0.6887374624260878 0.9197881641778576 0.3576834696125601 1.0 1.0 3 P50542 1 +Hip pain 0.56736356870616 0.9186882763139228 0.3582586436670625 1.0 1.0 5 P02545,O75844 2 +Progressive peripheral neuropathy 0.6882770870337354 0.9180323812427496 0.3586019134308795 1.0 1.0 3 P07602,O43681 2 +Vegetative state 0.6882770870337354 0.9180323812427496 0.3586019134308795 1.0 1.0 3 P07602,O43681 2 +Abnormal upper limb bone morphology 0.3127531676568936 0.9171002566191316 0.3590901066112273 1.0 1.0 107 P55011,Q7RTS9,Q9NX62,Q2M1P5,P50542,P42858,Q9UQE7,Q9H3S7,P31749,Q96AY3,Q32P28,Q14739,Q15233,Q9UHX1,Q96PZ0,P98175,P25054,Q08J23,Q13868,P16435,Q8NCM8,Q8WVQ1,Q9UGU0,O00116,O75844,Q7LGA3,Q9BXW9,Q8N3R9 28 +Increased intracranial pressure 0.3973860338206217 0.913807709494112 0.3608178947258804 1.0 1.0 21 P31749,Q9NZ08,P25054,P07602,Q969G3,Q15437 6 +Increased bone mineral density 0.4014119310033108 0.9121788270798136 0.3616745877860059 1.0 1.0 26 Q14739,Q13126,Q15392,Q15125 4 +Delayed closure of the anterior fontanelle 0.4521725765548035 0.9118352112295302 0.3618554715368005 1.0 1.0 13 O75381,Q9Y487 2 +Neoplasm of the respiratory system 0.4333192139834953 0.9111050722436552 0.3622400141620039 1.0 1.0 16 P30154,Q01844,P31749 3 +Elbow flexion contracture 0.4001421985637708 0.9077018168708808 0.364035783781655 1.0 1.0 25 Q96AY3,Q7LGA3,P50402,P16435,Q8WXH0 5 +Papilledema 0.3999360142958519 0.9060716800956444 0.3648979137562387 1.0 1.0 25 P55011,Q9H3S7,Q96PZ0,P31749,P25054,Q7LGA3,P42858,Q8N3R9 8 +Biliary cirrhosis 0.5301295680509771 0.9060445814258924 0.3649122561911488 1.0 1.0 6 Q14739,P09601 2 +Abnormality of the posterior pituitary 0.4834338673107269 0.9054619970729888 0.3652206840962706 1.0 1.0 10 Q9UHX1 1 +Decreased activity of mitochondrial complex iv 0.4244668251201856 0.9053097959342528 0.3653012882161734 1.0 1.0 17 Q9Y2R0,P13073,Q70HW3 3 +Axonal degeneration 0.5076847261074771 0.9026638088219524 0.366704349835204 1.0 1.0 8 P50570,Q6DKK2,Q9BQT8 3 +Echolalia 0.4828530561775359 0.9023165394362074 0.3668887420692983 1.0 1.0 10 Q01082,Q9UHX1 2 +Axial muscle weakness 0.5284581767101724 0.898316440942599 0.3690168698436764 1.0 1.0 6 Q8TD16,Q9H9S5,Q9Y5P6 3 +Telecanthus 0.4021660529986168 0.8962821753686881 0.3701020765113401 1.0 1.0 39 Q96D09,Q86XL3,Q8NCH0,Q03164,O75844,Q96EK5 6 +Nevus 0.4016848484163787 0.8944933849200283 0.3710579675458592 1.0 1.0 31 P31749,Q96AY3,Q71SY5,Q15437,P49815,Q9Y4P3,Q15056,Q9UQE7,Q01082,Q9UHX1 10 +Abnormality of metacarpal epiphyses 0.5616583350108675 0.8939273898352136 0.3713607419327158 1.0 1.0 5 P16435,O95202 2 +Ventricular tachycardia 0.4225629194641929 0.8922044910041048 0.3722833354582264 1.0 1.0 17 O43772,P0DP25,P46976,Q99996,Q14BN4,P09493 6 +Impaired proprioception 0.4012996443332569 0.8888602854485814 0.3740781716271217 1.0 1.0 39 P00846,P07196,Q9H0B6,Q9NR77,Q9H6K4 5 +Abnormality of corneal size 0.3976475133969945 0.8874393619158499 0.3748423994095664 1.0 1.0 46 Q9Y5P6,Q96EK5,Q9Y4P3,Q15056,Q9UQE7,O95202,Q15125,Q9H2M9,Q9NWM8,Q8NCH0,O75845,Q9ULC3,Q71SY5,Q9P273,Q13045,P49711,Q15555,Q9H9S5,Q15042,O43505 20 +Widely patent fontanelles and sutures 0.5598442395779232 0.8860702253523854 0.375579686365475 1.0 1.0 5 O75844,P98175 2 +Bladder neoplasm 0.4923535766218759 0.885395374630745 0.3759434261957417 1.0 1.0 9 P31749,P25054,P78549 3 +Macrodontia 0.3946996133755693 0.8851650883123241 0.376067598667464 1.0 1.0 22 P55011,Q9H3S7,Q96PZ0,Q00577,Q9UID3,Q7LGA3,P42858,Q8N3R9 8 +Preaxial polydactyly 0.4291293395625365 0.8832255093535937 0.3771144415622061 1.0 1.0 16 O75419,Q2M1P5,Q8NCM8,Q9BXW9,Q9UPP1,Q9UHX1 6 +Abnormal larynx morphology 0.4000808059412603 0.8814159599270079 0.3780927224502888 1.0 1.0 31 P25054,P07602,P21964,P16435,Q8NCM8,Q14739,Q01082,Q96HY6,Q9UHX1 9 +Bifid scrotum 0.5032894199202946 0.8807657514315507 0.3784446203828138 1.0 1.0 8 Q96EK5,P16435 2 +Broad foot 0.4785308104619892 0.8789333152808085 0.3794374336582657 1.0 1.0 10 Q7RTS9 1 +Angiofibromas 0.5122696277970302 0.8707845506583431 0.3838718023447949 1.0 1.0 7 P49815,Q15437,P31749 3 +Adenoma sebaceum 0.5122696277970302 0.8707845506583431 0.3838718023447949 1.0 1.0 7 P49815,Q15437,P31749 3 +Arm dystonia 0.6757244165432432 0.8703703810603506 0.384098027695734 1.0 1.0 3 Q99720 1 +Rod cone dystrophy 0.3988547637476355 0.8702377955413934 0.3841704650353823 1.0 1.0 40 P00846,O75381,Q15067,P03886,Q13868,P38435 6 +Abnormal muscle fiber alpha dystroglycan 0.8091151228174045 0.8684235327910369 0.3851625166909287 1.0 1.0 2 Q9H9S5 1 +Abnormality of the tongue muscle 0.8091151228174045 0.8684235327910369 0.3851625166909287 1.0 1.0 2 Q9H9S5 1 +Calf muscle pseudohypertrophy 0.8091151228174045 0.8684235327910369 0.3851625166909287 1.0 1.0 2 Q9H9S5 1 +Decreased cervical spine mobility 0.8091151228174045 0.8684235327910369 0.3851625166909287 1.0 1.0 2 Q9H9S5 1 +Fusion of the cerebellar hemispheres 0.8091151228174045 0.8684235327910369 0.3851625166909287 1.0 1.0 2 Q9H9S5 1 +Nephronophthisis 0.555594128790091 0.8676948572704496 0.3855614019441868 1.0 1.0 5 Q7Z4L5 1 +Arthrogryposis multiplex congenita 0.3991194291567597 0.8671644721104733 0.3858518994505806 1.0 1.0 35 P06753,Q96AY3,Q8NCH0,Q8TD16,Q15392,Q99567,O75844 7 +Laryngomalacia 0.4099959711577765 0.8653424973709737 0.3868508320181916 1.0 1.0 18 Q92890,O00192,P25054,Q2M1P5,P02545,P07602,P21964,P16435 8 +Serositis 0.3918346293187059 0.8628775819214696 0.3882047776357793 1.0 1.0 22 Q14C86,Q9NZ08,O43707,Q8N1F7 4 +Pelvic kidney 0.4878602197488629 0.8621260256950399 0.3886181711614169 1.0 1.0 9 Q9Y4P3,Q9BXW9,Q9UHX1 3 +Duplication of the distal phalanx of the thumb 0.8073394495412866 0.8618791234869886 0.3887540382022789 1.0 1.0 2 Q8WVQ1 1 +Partial duplication of the distal phalanges of the hand 0.8073394495412866 0.8618791234869886 0.3887540382022789 1.0 1.0 2 Q8WVQ1 1 +Optic neuropathy 0.3936499919520565 0.8564466532022821 0.3917507686819492 1.0 1.0 25 P00846,P03886,O96000,O43676,Q86Y39 5 +Abnormal muscle glycogen content 0.5528605047277986 0.8559014607684983 0.392052286905705 1.0 1.0 5 P13807,P46976 2 +Elevated systolic blood pressure 0.8052678307191499 0.8542577617538061 0.3929621849227609 1.0 1.0 2 P35611 1 +Elevated diastolic blood pressure 0.8052678307191499 0.8542577617538061 0.3929621849227609 1.0 1.0 2 P35611 1 +Elevated mean arterial pressure 0.8052678307191499 0.8542577617538061 0.3929621849227609 1.0 1.0 2 P35611 1 +Joint hemorrhage 0.8049718851731302 0.8531702235685966 0.3935649133455894 1.0 1.0 2 P38435 1 +Menorrhagia 0.8049718851731303 0.8531702235685962 0.3935649133455896 1.0 1.0 2 P35579 1 +Delayed gross motor development 0.3108605378359703 0.8524986300652039 0.3939373990330947 1.0 1.0 111 P55011,P48449,Q9H0B6,Q03164,Q96D71,Q03252,P50570,Q10713,P42858,Q9H3S7,Q01105,Q15233,Q9P2J5,Q96PZ0,Q8NCH0,Q05086,Q96N66,P61978,P35609,Q99720,Q9UGU0,Q9UID3,P35637,Q9H9S5,Q8N3R9,Q7LGA3,Q10471,Q14696,Q15058,Q01433,Q9UBB6 31 +Postaxial hand polydactyly 0.4372720082217367 0.8522388440453486 0.3940815412898755 1.0 1.0 14 Q7Z4L5,Q14739,O75845,Q8NCM8,Q10713 5 +Short long bone 0.396921219684877 0.8513963964651932 0.3945491928322635 1.0 1.0 39 Q7Z4L5,Q7RTS9,Q8WVQ1,P98175,P25054,O00116,Q8NCM8,Q9BXW9,Q96HY6,Q9UHX1 10 +Sporadic 0.3937115179770336 0.8510832186337863 0.3947231267113795 1.0 1.0 26 Q9BWD1,O60333,Q05086,P31749 4 +Polyphagia 0.4600979507244647 0.8501754503810645 0.3952275484107086 1.0 1.0 11 Q4J6C6,O95155,Q05086 3 +Neonatal hypoglycemia 0.4730345343650717 0.8492675548400134 0.3957324303664262 1.0 1.0 10 O43772,P31751 2 +Gait ataxia 0.355524283310194 0.8479227965125278 0.3964809678897019 1.0 1.0 70 P00846,Q13501,P07196,Q9Y4W6,Q9UBB4,Q9NR77,Q9UID3,Q9P0J1,Q05086,P03886,P07602,O43681,Q96BR5,Q03252,O15020,P42858,Q10713,Q8IY17 18 +Abnormal renal tubule morphology 0.3925256636251455 0.8475875232533377 0.3966677252318979 1.0 1.0 25 P03886 1 +Orofacial dyskinesia 0.5072611329846031 0.8468655406579232 0.397070071578149 1.0 1.0 7 Q9BPX6 1 +Abnormal morphology of the musculature of the neck 0.4413267184634145 0.8459454356471666 0.3975831841799742 1.0 1.0 13 Q99720,P35637 2 +Abnormal heart rate variability 0.5894543392572585 0.8430061131306803 0.3992250248882856 1.0 1.0 4 P07602,Q9NZJ7 2 +Oval face 0.5163546579310462 0.8425577041016648 0.3994758544820471 1.0 1.0 6 Q9UHX1 1 +Ventricular arrhythmia 0.393582175616923 0.8394284956620518 0.4012288988384775 1.0 1.0 44 P00846,O43772,P49815,O60333,P00403,P0DP25,P03886,P50402,P09493,Q8WXH0 10 +Broad phalanx of the toes 0.4834357851549642 0.8392675292701244 0.401319200124449 1.0 1.0 9 Q7LGA3 1 +Emg myopathic abnormalities 0.3943648186579237 0.8381127345191363 0.4019673914865227 1.0 1.0 30 Q9BTV4,Q13501,P07196,P06753,Q7Z406,P02545,P31483,Q9H9S5,P50402,P46976,Q9Y6B6,P50570,Q8WXH0 13 +Abnormal arterial physiology 0.3932634976033979 0.8373355185956278 0.4024039995834412 1.0 1.0 28 Q9NWM8,O75844,Q9NZ08,Q9Y3Z3 4 +Calcinosis 0.5150614445121029 0.8366237319477521 0.4028041015412384 1.0 1.0 6 Q14739,O75844 2 +Hypopigmentation of the fundus 0.5477671371328603 0.8339845705350571 0.404289678568138 1.0 1.0 5 P49815,P38435,Q2M1P5 3 +Complete atrioventricular canal defect 0.6655320569472292 0.8320009395161516 0.4054084141976508 1.0 1.0 3 Q9UHX1 1 +Abnormality of circulating adrenocorticotropin level 0.4564717759427948 0.8297615812696806 0.4066735963122521 1.0 1.0 11 Q13423,P16435,P31749 3 +Allergy 0.5036520650714734 0.8296742939518345 0.4067229591515706 1.0 1.0 7 P00813 1 +Heterogeneous 0.3895311033737139 0.8283182249779931 0.4074903041918487 1.0 1.0 48 P00846,P07196,P06753,P31749,O60333,Q9NR77,P25054,P03886,O75844,Q9BQE5,P49815 11 +Degeneration of the lateral corticospinal tracts 0.5131145996373978 0.8277000314257678 0.4078404013406187 1.0 1.0 6 O75298,Q13501,P35637 3 +Abnormal sclera morphology 0.392430879453014 0.8263243676414382 0.408620114165918 1.0 1.0 29 P31749,Q96AY3,Q8NCH0,O75718,P06132,Q96EK5 6 +Distal peripheral sensory neuropathy 0.5455980829274288 0.8246748386976508 0.4095562202908098 1.0 1.0 5 P03886 1 +Prominent digit pad 0.3882002850328154 0.8135620118977142 0.4158959077184705 1.0 1.0 25 P55011,Q9H3S7,Q96PZ0,Q7LGA3,P42858,P55795,Q8N3R9 7 +Visual acuity test abnormality 0.5098905784216097 0.8129482858751587 0.4162477085812148 1.0 1.0 6 P31749 1 +Urinary bladder sphincter dysfunction 0.4893961541065452 0.8118886770890911 0.4168555121706956 1.0 1.0 8 Q9NR77 1 +Prolonged bleeding time 0.4992333952110697 0.8086821025145261 0.4186980254465475 1.0 1.0 7 Q86YV9 1 +Orthostatic hypotension due to autonomic dysfunction 0.4772791800413904 0.8075604066605954 0.4193436871078817 1.0 1.0 9 P20700,P07602,O43681,Q04637,Q96QK1 5 +Tracheal stenosis 0.5086982405893207 0.8075012308783102 0.4193777656529995 1.0 1.0 6 Q96HY6,Q15125 2 +Ichthyosis 0.3919748468133537 0.8071790609242253 0.4195633276059163 1.0 1.0 36 P48449,O75381,P40855,Q15125,O95721,Q15800,P02545,P50402,P50542,O95470,Q8WXH0,P51648,Q9Y5Y5 13 +Recurrent paroxysmal headache 0.464904305030583 0.8055515684779221 0.4205014607008182 1.0 1.0 10 O60333,P03886 2 +Enlarged kidney 0.5077685429172452 0.8032573330825327 0.4218260135586367 1.0 1.0 6 Q96AX1,Q8NCM8,P16930 3 +Rotary nystagmus 0.5405805687203683 0.8031974156560265 0.4218606390075452 1.0 1.0 5 O94905,Q9NVS9,Q5T8D3,Q9Y4R8 4 +Optic disc hypoplasia 0.5077150401666113 0.8030131925048599 0.4219671094470194 1.0 1.0 6 Q9H3H1,P25054 2 +Receptive language delay 0.4009310986894234 0.8009758637145935 0.4231456189504574 1.0 1.0 18 P55011,Q9H3S7,Q96PZ0,Q7LGA3,P42858,Q8N3R9 6 +Ectopic kidney 0.4165888538431117 0.8001303741983384 0.4236352644981669 1.0 1.0 16 Q9UHX1 1 +Paroxysmal involuntary eye movements 0.3824603010959308 0.7983901043271164 0.4246441440256909 1.0 1.0 21 O43676,Q86Y39,O96000,P03886 4 +Axonal degeneration regeneration 0.538991914934756 0.7964148986233632 0.4257909214398951 1.0 1.0 5 Q8TB36,O60333 2 +Crumpled long bones 0.7892867712340955 0.7959957443596408 0.426034508937493 1.0 1.0 2 O75718 1 +Unusual infection by anatomical site 0.4366550235688004 0.7937682467132021 0.4273303613362507 1.0 1.0 12 Q9NZ08 1 +Tetraplegia tetraparesis 0.385664522743907 0.7931100333416305 0.427713717679927 1.0 1.0 48 P00846,Q7RTS9,Q13423,Q9UBX3,O95831 5 +Blue sclerae 0.3825665998221934 0.7910394972085505 0.4289209434064305 1.0 1.0 22 Q96AY3,Q96EK5,Q8NCH0,O75718 4 +Biconcave vertebral bodies 0.5371630220286967 0.788617721452785 0.4303354701153647 1.0 1.0 5 Q96AY3 1 +Decreased circulating cortisol level 0.4614757789105619 0.7871849393912194 0.4311736122455287 1.0 1.0 10 Q13423,P31749 2 +Abnormal diaphysis morphology 0.3374013532085669 0.7869173140214876 0.4313302713345055 1.0 1.0 75 Q7RTS9,Q9NX62,O00170,O75312,Q96AY3,Q9NR77,Q9HC07,Q32P28,Q14739,Q8N0X7,Q01082,Q13126,Q9Y487,P16435,Q8NCM8,Q96HY6,Q8WVQ1,O75718,Q7LGA3 19 +Myopathic facies 0.5038267742073044 0.7852973430044141 0.4322792532831516 1.0 1.0 6 Q969X5,P06753,Q9Y5P6,Q00577 4 +Proportionate short stature 0.3891019163763405 0.7831958283004578 0.4335121242824742 1.0 1.0 36 Q5JRA6,Q16836,Q7RTS9,Q8WVQ1,O75419,Q96EY7,Q15392,Q14739,Q96HY6,Q8IY17 10 +Hyperconvex nail 0.4831808668602186 0.7812768610345171 0.4346396762670135 1.0 1.0 8 P51812,P42892,O95202 3 +Delusions 0.3800870462931709 0.7801414649120652 0.4353076120952432 1.0 1.0 21 O60220,P49770,O43681,P21964,Q96DF8,Q9BQE5,P42858 7 +Intestinal hypoplasia 0.5737169712967447 0.779842103878749 0.4354838201398026 1.0 1.0 4 O75844 1 +Atrophic scars 0.492814952269255 0.7783088041330922 0.4363869864538376 1.0 1.0 7 Q9NWM8 1 +Abnormal aortic valve cusp morphology 0.3825742562295991 0.7761907205574781 0.4376363842634285 1.0 1.0 24 Q6PGP7,Q9UHX1,P61978,Q9Y4P3,Q9UQE7,Q01082,O15294 7 +Sirenomelia 0.7836638058597247 0.7757367313669641 0.4379044473043723 1.0 1.0 2 P31749 1 +Abnormal talus morphology 0.3792841606863433 0.7739757562103148 0.4389451282125756 1.0 1.0 21 O75844,Q99567,P16435,Q15058,Q9UHX1 5 +Abnormal circulating androgen level 0.4246161371254139 0.7736130576587846 0.4391596479619402 1.0 1.0 14 Q13423,P31749 2 +Kyphosis 0.3334857121375909 0.773395434447745 0.4392883911223246 1.0 1.0 159 P55011,O95155,Q7RTS9,Q5MNZ6,Q9H0B6,Q9BT22,O00170,P42858,Q8WXH0,P51648,Q9H3S7,Q15125,P31749,Q96AY3,Q9NR77,Q9HC07,Q32P28,Q8TD16,Q99567,Q9NWM8,Q14739,Q15233,Q8N0X7,Q01082,Q9UHX1,Q96PZ0,Q8NCH0,Q9Y487,O60826,Q15437,Q8IWS0,O95831,Q71SY5,Q8WVQ1,P06753,Q9H9S5,O75844,Q7LGA3,P50402,Q8N3R9,Q9UPP1 41 +Dysmetric saccades 0.5332910954535832 0.7721507225477129 0.4400251634173298 1.0 1.0 5 Q9Y4W6 1 +Abnormal pericardium morphology 0.4290565723682337 0.7718625587069964 0.4401958349297621 1.0 1.0 13 P47985,Q9NZ08,O15460,P02545,P49815,P14174 6 +Pectus excavatum 0.3154371278437058 0.7714046618352022 0.4404671127377628 1.0 1.0 82 P06753,P31749,Q8NCH0,Q9Y487,Q96A33,P78318,Q03164,Q7LGA3,P50402,P61978,Q8WXH0,Q9UHX1 12 +Glomerular sclerosis 0.3875637268364861 0.7711325709598185 0.4406283564753024 1.0 1.0 35 P16930,O60333,P00403,Q14C86,P03886,Q8N1F7,O95470 7 +Abnormality of the mitochondrion 0.2989980219161826 0.7708271725144794 0.4408093789089999 1.0 1.0 101 Q16836,Q70HW3,Q9Y4W6,P03886,P42704,Q86Y39,P00846,O43772,O00429,P56556,O43676,Q13501,P00403,O96000,P13073,O75880,Q9Y2R0,Q4J6C6,Q9P0J1,Q9GZY8,P35637,Q9UBX3 22 +Fatty replacement of skeletal muscle 0.4809154484843574 0.7701549878527996 0.4412079610029134 1.0 1.0 8 Q9H9S5,Q8NFF5,Q7Z406 3 +Abnormality of skull ossification 0.4454225410235152 0.7678413149353448 0.4425814658384646 1.0 1.0 11 O75718,O75844,Q32P28 3 +Left ventricular hypertrophy 0.3844844664837381 0.7673682317159901 0.4428626110806668 1.0 1.0 28 P35609,O75880,P00403,O75208,P03886,Q9H9S5,O00170,Q15233 8 +Aplasia hypoplasia of the phalanges of the toes 0.5319346996602298 0.7663954857369693 0.4434410180480488 1.0 1.0 5 P02545,Q9ULC3,P21281 3 +Eyelid myoclonus 0.4570991617861675 0.7638060064904549 0.4449828568756753 1.0 1.0 10 Q01105,Q08209 2 +Nocturnal seizures 0.7801124593074902 0.7630110574076179 0.4454568014622502 1.0 1.0 2 Q01082 1 +Poor speech 0.2958414704632525 0.7620313814669187 0.4460412748031603 1.0 1.0 97 P55011,O95155,Q7RTS9,Q9Y5P6,Q08209,Q9NVI7,Q10713,P42704,Q9UQE7,P56556,Q01105,P15311,Q15233,Q96CU9,Q13501,Q9Y487,Q05086,Q96N66,Q08J23,P61978,O60826,P49815,Q71SY5,Q9BRT2,Q9H9S5,Q15058 26 +Abnormal lung lobation 0.410689842024058 0.7612757965143043 0.4464923539263226 1.0 1.0 16 Q14739,Q9UHX1,P31749 3 +Palpebral edema 0.5303299853026714 0.7595959096319972 0.4474961648832565 1.0 1.0 5 Q01082,O00170 2 +Congenital hip dislocation 0.3833184454372103 0.7581104935000973 0.4483848382513931 1.0 1.0 28 Q8TD16,Q9Y487,Q9UHX1 3 +Fatigable weakness of swallowing muscles 0.4219352834277687 0.7570457945666206 0.4490224271089227 1.0 1.0 14 Q68CQ7,Q92804,Q15165,P35637 4 +Sclerosis of hand bone 0.777744894939334 0.7545581761227912 0.4505141265295838 1.0 1.0 2 Q15125 1 +Prominent umbilicus 0.7777448949393339 0.7545581761227897 0.4505141265295846 1.0 1.0 2 O75844 1 +Severe failure to thrive 0.7777448949393339 0.7545581761227897 0.4505141265295846 1.0 1.0 2 O75844 1 +Aplasia hypoplasia of the colon 0.7777448949393339 0.7545581761227897 0.4505141265295846 1.0 1.0 2 O75844 1 +Second degree atrioventricular block 0.7777448949393339 0.7545581761227897 0.4505141265295846 1.0 1.0 2 P0DP25 1 +Stiff skin 0.7777448949393339 0.7545581761227897 0.4505141265295846 1.0 1.0 2 O75844 1 +Epidermal hyperkeratosis 0.7777448949393339 0.7545581761227897 0.4505141265295846 1.0 1.0 2 O75844 1 +Dysmenorrhea 0.7777448949393337 0.7545581761227883 0.4505141265295855 1.0 1.0 2 O00170 1 +Aplasia involving bones of the lower limbs 0.7777448949393337 0.7545581761227883 0.4505141265295855 1.0 1.0 2 Q8NCM8 1 +Aplasia of the phalanges of the hand 0.7777448949393337 0.7545581761227883 0.4505141265295855 1.0 1.0 2 Q9BXW9 1 +Abnormality of the humerus 0.4093278735989348 0.75233067916349 0.4518522226800963 1.0 1.0 16 Q7RTS9,P16435 2 +Adducted thumb 0.3817191118139363 0.7507149438970369 0.4528242274748151 1.0 1.0 27 Q86XL3 1 +Abnormal shoulder morphology 0.3847834494327376 0.749610178034375 0.4534895190434818 1.0 1.0 34 P55011,Q7RTS9,Q9UGU0,Q9H3S7,Q96PZ0,P02545,Q8N3R9,Q7LGA3,P42858,Q9Y4P3,Q15056 11 +Abnormal 2nd finger morphology 0.4764606781986522 0.7483453420990193 0.454251881778732 1.0 1.0 8 Q9H6K4,Q71SY5 2 +Asymmetry of the thorax 0.775969221663217 0.7482350980532387 0.454318364097342 1.0 1.0 2 P31749 1 +Bilateral cryptorchidism 0.4418090958617282 0.7476987272108058 0.4546418990595484 1.0 1.0 11 P78318,P48449,Q15233 3 +Cardiac conduction abnormality 0.384699823567578 0.7474536203111757 0.4547897889508032 1.0 1.0 35 P00846,O43772,P00403,P0DP25,P03886,P50402,Q8WXH0 7 +Hypotriglyceridemia 0.7750813850251581 0.7450789655507867 0.4562239842375613 1.0 1.0 2 Q10471 1 +Increased hepatocellular lipid droplets 0.7750813850251581 0.7450789655507867 0.4562239842375613 1.0 1.0 2 P42704 1 +Hypolipidemia 0.7750813850251581 0.7450789655507867 0.4562239842375613 1.0 1.0 2 Q10471 1 +Scaphocephaly 0.5648067849180325 0.7444767174102855 0.4565881216044283 1.0 1.0 4 P40855 1 +Aplasia hypoplasia involving the pelvis 0.4080560784463673 0.7439871869543647 0.4568842267823543 1.0 1.0 16 Q8WVQ1,O95831,Q96HY6,P50542 4 +Retinal arteriolar tortuosity 0.42439769288669 0.7439002079685811 0.4569368495610724 1.0 1.0 13 P00846,O00192,P21964,Q9Y4P3,Q15056 5 +Abnormality of the antitragus 0.6417365674653537 0.7438048460555932 0.456994547971258 1.0 1.0 3 Q8IY17 1 +Thin ribs 0.4141493358017923 0.742608997611256 0.4577184395036697 1.0 1.0 15 Q08209,Q32P28,P02545,O75844,P50570,O95831 6 +Macroorchidism 0.4940143281834434 0.7408444321644466 0.4587877711070014 1.0 1.0 6 P38159,P31749 2 +Rigidity 0.3737988379114481 0.7384208181990394 0.4602587677017768 1.0 1.0 54 P00846,Q06787,Q96CU9,O43464,Q9Y3Z3,Q9Y287,Q08209,Q9Y4W6,Q14203,Q9NQX3,Q96EY7,O43681,Q15392,P07602,P42858,Q96QK1,Q9H6K4,Q9BPX6 18 +Abnormal macroscopic urine appearance 0.3755542019660327 0.7370205479037787 0.4611098537792117 1.0 1.0 22 Q8N1F7,P49815,Q14C86,P06132 4 +Incoordination 0.3357234730309165 0.7353446261362293 0.4621296364287821 1.0 1.0 74 Q7RTS9,Q9Y5P6,Q9UBB4,O43681,P42858,Q10713,P00846,Q9NR77,Q01105,Q13501,Q99707,Q05086,Q6DKK2,Q9UGU0,P06753,Q15067,P07602,Q9H9S5,O15020,Q96QK1 20 +Abnormal circulating methionine concentration 0.49268996234529 0.7348750693188794 0.4624155829221144 1.0 1.0 6 Q6PGP7,P16930 2 +Abnormality of subcutaneous fat tissue 0.3994029709862802 0.733932027346626 0.4629901662525 1.0 1.0 17 Q9Y487,P31749 2 +Hyperesthesia 0.6382510939312147 0.7310722193622385 0.4647350419041582 1.0 1.0 3 P07602 1 +Abnormal atrioventricular conduction 0.3985208390461453 0.7279587775561962 0.4666388208532637 1.0 1.0 17 P35609,O43772,P0DP25,P02545,P50402,Q99996,Q14BN4,Q8WXH0 8 +Pes cavus 0.2963894882770599 0.723235740466157 0.4695350643752034 1.0 1.0 102 P55011,Q8NI60,Q9H0B6,O60313,Q96D71,P50542,P50570,Q10713,P42858,Q9H3S7,P05023,O00429,O60333,Q9NR77,Q14739,Q9H6K4,Q8N0X7,Q96PZ0,Q08J23,O95831,Q71SY5,Q99720,O75298,Q9UGU0,P07196,P06753,Q96BR5,Q7LGA3,Q8N3R9 29 +Epistaxis 0.4162928882345416 0.7222970834164025 0.4701118456779594 1.0 1.0 14 Q86YV9,P35579,P38435 3 +Red eye 0.3896305484524941 0.7213356806386608 0.4707030091779938 1.0 1.0 18 P28070 1 +Loss of ability to walk 0.4158822626164594 0.7197750902045672 0.4716634842981548 1.0 1.0 14 P00846,Q9H9S5 2 +Restless legs 0.6339390767564741 0.7153933684497288 0.4743660090735599 1.0 1.0 3 P07196 1 +Aphasia 0.3788366876559331 0.7139430113082241 0.4752624195268167 1.0 1.0 45 P55011,Q13501,Q9UGU0,Q9H3S7,Q96PZ0,O00429,P00403,P03886,P21964,Q7LGA3,P42858,Q8N3R9 12 +Abnormality of the temporomandibular joint 0.556546593080689 0.7119854263403209 0.4764738006520164 1.0 1.0 4 O75844 1 +Constriction of peripheral visual field 0.3721872204630667 0.711210373924531 0.4769538810134812 1.0 1.0 22 P00846,O75381,P40855,O60220,O60313 5 +Intellectual disability mild 0.3144646504773237 0.7111856596798775 0.4769691937834968 1.0 1.0 133 P55011,Q7RTS9,Q08209,Q9Y4W6,Q9BT22,Q15800,Q8WWV3,P21964,P42858,Q10713,Q5JRA6,P00846,Q9H3S7,P31749,Q01105,P15311,Q15233,Q8N0X7,Q8IY17,Q96PZ0,P25054,Q05086,Q08J23,Q13868,Q6PGP7,Q71SY5,Q5JRX3,P16615,Q9H9S5,Q7LGA3,O15020,Q6P4A7,Q8N3R9,Q9UPP1 34 +Bell shaped thorax 0.6325818119633693 0.7104755041338479 0.4774093160663288 1.0 1.0 3 Q96HY6 1 +Hyperthyroidism 0.4223491131973326 0.7102334115173075 0.4775594048911316 1.0 1.0 12 Q06787,P31749,O00192,Q92890,P21964 5 +Headache 0.3406727768039872 0.7067701149557375 0.4797093491660087 1.0 1.0 71 P00846,Q9Y3Z3,P31749,O00429,O60333,Q9NZ08,P00403,P25054,Q14C86,P03886,O60313,Q8N1F7 12 +Polymicrogyria 0.3005341185488246 0.702686083248429 0.4822514024011204 1.0 1.0 85 P55011,P40855,Q9Y5P6,Q08209,P50542,Q10713,Q96EK5,O75381,O95721,Q8TD16,Q15392,Q01105,P15311,Q16625,Q8WXW3,Q9Y5Y5,Q9Y487,Q96N66,Q08J23,P21281,Q71SY5,Q9NQX3,Q9H9S5 23 +Microcytic anemia 0.4667423516562305 0.7010748655638552 0.4832562950424397 1.0 1.0 8 Q9UBX3,P22830 2 +Megalocornea 0.4125649547987953 0.6994374224378023 0.4842787077283712 1.0 1.0 14 Q9Y5P6,O95202,Q9H9S5,Q96EK5,Q9Y4P3 5 +Memory impairment 0.3786752441643983 0.6992223427649699 0.4844130896671292 1.0 1.0 41 Q13501,P31749,Q9Y4W6,P49770,Q9NZ08,P00403,P03886,P07602,O43681,P31483,P43246,Q969G3,P42858 13 +Neck muscle weakness 0.3941156430809672 0.6982077204498474 0.485047298948398 1.0 1.0 17 Q99720,P06753,Q9Y5P6,P35637,P02545,P07602,P46976 7 +Weakness of muscles of respiration 0.3781579043581144 0.6977301191238998 0.4853459884788811 1.0 1.0 33 Q7RTS9,Q15067,Q8TD16,P50402,Q8WXH0,O95831 6 +Abnormality of the ribs 0.3443686688599309 0.6971719312051347 0.4856952026315937 1.0 1.0 69 Q7Z4L5,O95155,Q7RTS9,Q08209,P25054,Q32P28,Q03164,O75718,O75844,P16435,Q14739,O95831,P00813,Q96HY6,Q9UHX1 15 +Ecchymosis 0.4198621985520623 0.69581780931076 0.4865429346168182 1.0 1.0 12 Q8NCH0 1 +Distal muscle weakness 0.3393622959262258 0.6919076319708116 0.4889953374885907 1.0 1.0 71 Q9Y5P6,O15269,Q9Y4W6,P31483,P46976,P50570,P00846,O60333,Q9NR77,Q9BQT8,Q8TB36,Q8TD16,Q8IY17,Q13501,Q14203,O95831,Q71SY5,P35609,Q99720,P07196,P06753,Q7Z406,P35637,P02545,Q96BR5 25 +Prolonged qtc interval 0.6272060133834232 0.6910812046349808 0.4895145111125036 1.0 1.0 3 P0DP25 1 +Abnormal meningeal morphology 0.3705101375660317 0.6903438557598001 0.4899779747305834 1.0 1.0 23 O75845,Q9H9S5,P21964,Q10713,Q9UHX1 5 +Pulmonary infiltrates 0.4641770176946954 0.6886746527282287 0.4910280305945451 1.0 1.0 8 Q9NZ08 1 +Multicystic kidney dysplasia 0.3668800718485666 0.6883686760814932 0.4912206442476619 1.0 1.0 20 O75381,P40855,P50542,Q10713,Q9UQE7 5 +Chorea 0.2994673961252678 0.687996644178954 0.4914548946333452 1.0 1.0 85 P00846,Q99720,Q08209,Q9BWD1,P03886,P35637,Q01105,P42858,Q9H6K4,Q71SY5,Q9BPX6 11 +Lumbar kyphosis 0.758804379994084 0.6878900362694667 0.4915220315008453 1.0 1.0 2 P51812 1 +Osteoarthritis 0.4184870127435509 0.687861829578095 0.4915397956303957 1.0 1.0 12 Q8WVQ1,O75844,Q96HY6,O00170 4 +Single transverse palmar crease 0.3747198475303192 0.6878415263602174 0.4915525824902726 1.0 1.0 47 O75381,P40855,O95202,Q9UID3,P98175,P25054,Q71SY5,P50542,Q9UQE7,Q01082,Q8IY17,Q9UHX1 12 +Gray matter heterotopia 0.377265044795097 0.6862726996000384 0.4925411611234633 1.0 1.0 35 Q86XL3,P31749,Q66GS9,Q2TAA5,Q9H9S5,Q9UEY8,P61978,P07942,Q15058,Q9BSJ2 10 +Abnormality of limb epiphysis morphology 0.3760333860590813 0.6834926686509541 0.4942955812520855 1.0 1.0 32 Q5JRA6,Q7RTS9,Q8WVQ1,Q7LGA3,P16435,P50542,O95831 7 +Abnormality of exocrine pancreas physiology 0.404700819716954 0.6828858486611663 0.4946789767344646 1.0 1.0 15 Q9UHX1 1 +Pelvic girdle muscle weakness 0.4526101331980486 0.6820317308196729 0.49521888692032 1.0 1.0 9 Q9H9S5,P06753 2 +Bulbar palsy 0.4291217824690441 0.6774893518842371 0.4980955237879816 1.0 1.0 11 O43681,Q13501,P06753,P35637 4 +Shallow orbits 0.4509911996393897 0.6738983172395857 0.5003759620374097 1.0 1.0 9 P07237,O75844,P61978 3 +Abnormality of the umbilical cord 0.4507029822252402 0.6724519054163388 0.5012960482714417 1.0 1.0 9 O60826,O75844,P16435 3 +Horizontal ribs 0.6215199240944805 0.6707196743996805 0.5023991269010841 1.0 1.0 3 Q8NCM8 1 +Agenesis of corpus callosum 0.2870418876606818 0.6706198331063362 0.5024627445891889 1.0 1.0 93 O95155,Q86XL3,Q66GS9,P00403,P03886,P78318,Q15392,Q9H9S5,Q7LGA3,P61978,Q9UHX1 11 +Vertebral segmentation defect 0.3739099503711895 0.6700156925701003 0.5028477866334313 1.0 1.0 31 Q15125,O95202,Q9H9S5,P61978,P16435,O60826,Q9Y4P3,Q15056,P21281,Q9UHX1 10 +Abnormality of the lymph nodes 0.3751850545882297 0.6692420314307583 0.5033410983209343 1.0 1.0 35 P28070,Q9NZ08,Q01844,P49815,P00813,P33991 6 +Disproportionate tall stature 0.3741229546385129 0.6681432958647637 0.5040421271364579 1.0 1.0 32 P55011,Q9UGU0,Q9H3S7,Q96PZ0,P31749,Q8NCH0,Q7LGA3,P16435,P42858,Q9NWM8,Q8N3R9 11 +Diaphyseal thickening 0.6204854943753604 0.6670329180048633 0.5047511071449171 1.0 1.0 3 Q14739,P08236 2 +Central sleep apnea 0.4769584345038779 0.664602919846792 0.5063045012142986 1.0 1.0 6 Q96A33 1 +Soft skin 0.4591615302604626 0.6645340920936001 0.5063485364467353 1.0 1.0 8 Q9NWM8 1 +Cavernous hemangioma 0.4682009055458005 0.6634546314724863 0.5070394268011094 1.0 1.0 7 Q15437,P31749 2 +Abnormality of the phalanges of the hallux 0.4675957578118535 0.6606693727455715 0.5088243692758869 1.0 1.0 7 Q8WVQ1,Q9ULC3,Q2M1P5 3 +Cessation of head growth 0.4674565249177407 0.6600288345186758 0.5092353256120612 1.0 1.0 7 Q05086 1 +Contractures of the joints of the lower limbs 0.3664811043677731 0.6587753452153237 0.5100400416251696 1.0 1.0 53 Q99720,Q86XL3,Q96AY3,P35637,O60313,Q8TD16,Q9H9S5,Q7LGA3,P50402,Q8WXH0 10 +Arthritis 0.3733009701477258 0.6580317114759856 0.5105177543983801 1.0 1.0 43 P28070,Q8WVQ1,Q9Y3Z3,Q7Z406,Q9NZ08,O75844,P21964,Q14739,Q96HY6,P14174 10 +Fragile skin 0.4577183807110884 0.657614440274676 0.5107859132183785 1.0 1.0 8 Q8NCH0 1 +Butterfly vertebrae 0.6172291296625173 0.6554632918909516 0.5121695131211694 1.0 1.0 3 O75845,Q8N3U4 2 +Gaze evoked nystagmus 0.4359277402196259 0.6520094441088478 0.5143950799818833 1.0 1.0 10 Q9Y4W6,Q10713,O15020 3 +Abnormality of hand joint mobility 0.6159282602071212 0.6508570258976282 0.5151387844916253 1.0 1.0 3 P51812 1 +Hyperextensibility of the finger joints 0.6159282602071212 0.6508570258976282 0.5151387844916253 1.0 1.0 3 P51812 1 +Atrioventricular canal defect 0.45627608948511 0.6507112419225057 0.5152329048673576 1.0 1.0 8 O75419,Q9UHX1 2 +Acquired abnormal hair pattern 0.503433764772081 0.6473543264908037 0.5174026487283405 1.0 1.0 5 P25054 1 +Recurrent hand flapping 0.5033318344121598 0.6469359694508826 0.5176733850737851 1.0 1.0 5 P55795,Q05086,Q9UNW9 3 +Joint contracture of the hand 0.3573970440713111 0.6430371642714797 0.5201999852210561 1.0 1.0 59 O95155,P07196,P06753,Q9NR77,Q15392,Q99567,O75844,P16435,Q71SY5 9 +Porencephalic cyst 0.471762414128783 0.6416795479035715 0.5210812712557993 1.0 1.0 6 Q9Y3Z3 1 +Overlapping toe 0.3638681439256926 0.6396391993542664 0.5224071918143136 1.0 1.0 23 Q15125,P61978,Q96A33,Q9UHX1 4 +Abnormality of hair pigmentation 0.3657181454419795 0.6387339213607133 0.5229960415123096 1.0 1.0 25 Q13126,Q86YV9,Q05086,Q969F9,Q6PGP7 5 +Abnormal femoral neck morphology 0.3717650832996189 0.638271572091891 0.5232969139445849 1.0 1.0 38 Q7RTS9,Q8WVQ1,Q96AY3,Q9Y487,Q96A33,O75718,O75844,O95831,Q96HY6 9 +Fever 0.3021810122483226 0.6376192501377025 0.5237215615655542 1.0 1.0 83 P00846,P28070,Q9Y3Z3,O60333,Q9NR77,Q9NZ08,Q9HC07,P00403,Q14C86,P03886,P61978,Q8N1F7,O43707,Q14739,P49815,P00813,Q01082 17 +Dysdiadochokinesis 0.3973668972167569 0.6369509338012417 0.5241568043981126 1.0 1.0 15 Q06787,Q13501,Q6DKK2,Q9BUK6,P20700,Q9UBB4,Q9Y4W6,P18887,O15020,P41440 10 +Increased urine proteinogenic amino acid derivative level 0.7431192660550492 0.6341010826763036 0.5260148562513767 1.0 1.0 2 Q9NQX3 1 +Increased muscle lipid content 0.4323437421577382 0.6333398748621211 0.5265117191903164 1.0 1.0 10 Q8NI60,P06753 2 +Abnormality of the larynx 0.3655328005207642 0.6322472989406788 0.5272252946374199 1.0 1.0 51 Q13501,Q92804,Q15165,Q14203,Q68CQ7,Q2M1P5,P25054,P35637,P02545,P07602,P21964,P16435,Q8NCM8,Q14739,Q01082,Q96HY6,Q9UHX1 17 +Open mouth 0.3697476072073731 0.6298733341881987 0.5287774606660385 1.0 1.0 33 Q86XL3,Q9UGU0,Q96PZ0,P31749,Q00577,Q2M1P5,Q96DF8,P61978,Q10713,Q15233,P21281,O15294 12 +Abnormal urinary color 0.4688746121232781 0.629008154893669 0.5293437173980253 1.0 1.0 6 P49815 1 +Paranoia 0.4603253098780063 0.6273759101815662 0.5304128547997387 1.0 1.0 7 Q96DF8 1 +Abnormal morphology of myocardial trabeculae 0.4985457311687018 0.6273599917226302 0.5304232869535539 1.0 1.0 5 P35609 1 +Hydrocele testis 0.4506724147347486 0.6240127920183867 0.532619184174906 1.0 1.0 8 Q9UBX3 1 +Breast aplasia 0.5336413896366539 0.6236236069252954 0.5328748034468933 1.0 1.0 4 P02545,O75419 2 +Episodic tachypnea 0.4405833475941582 0.6219891792829128 0.5339489832052129 1.0 1.0 9 Q10713,Q8WXW3,P22695 3 +Dermal atrophy 0.3664161287151853 0.619790234085597 0.5353958990669117 1.0 1.0 29 Q9NWM8,Q15392,Q8NCH0 3 +Abnormal uvea morphology 0.2935116346833297 0.6172198031415119 0.537089755454818 1.0 1.0 109 O75381,O95155,P40855,P31749,Q86YV9,Q9NR77,O60333,Q05086,P78318,Q9H9S5,Q8WXW3,Q7LGA3,Q96EK5,Q8IY17,Q9UHX1 15 +Neoplasm of fatty tissue 0.4179319215949792 0.6163677059240388 0.5376518623215429 1.0 1.0 11 P25054,P31749 2 +Abnormal t wave 0.4953446868424324 0.6143437161552677 0.5389882201998173 1.0 1.0 5 Q99996,P0DP25 2 +Abnormalities of placenta or umbilical cord 0.3880715012565695 0.614326286867376 0.5389997352731728 1.0 1.0 16 O75844,P16435,O60826,Q6PGP7,P21281,Q01082 6 +Limb girdle muscle weakness 0.3633495579189522 0.6137047157393949 0.539410471600583 1.0 1.0 26 P06753,Q9Y5P6,Q13126,O60313,Q8TD16,P07602,Q9H9S5,O14979 8 +Colorectal polyposis 0.4283773204173319 0.6127801269580289 0.5400217329263264 1.0 1.0 10 P31749 1 +Aplasia hypoplasia of the phalanges of the hand 0.3555900673970866 0.6116118737003198 0.5407945803217546 1.0 1.0 58 Q5JRA6,Q7RTS9,P21281,Q8WVQ1,P51812,O60826,P02545,Q03164,O75844,P38435,P16435,Q969G3,Q14739,Q9BXW9,Q8IWS0,Q9UQE7,Q9UHX1 17 +Retinopathy 0.3629473374524213 0.6106158922266387 0.5414538991272724 1.0 1.0 26 P00846,Q9NZ08 2 +Hypermethioninemia 0.4943617781692279 0.6103597033725303 0.5416235556356197 1.0 1.0 5 Q6PGP7 1 +Muscle fiber inclusion bodies 0.4163007919015571 0.6075314925511718 0.5434982494744636 1.0 1.0 11 O43676,P07196 2 +Regional abnormality of skin 0.3153049251639595 0.6072648554203101 0.5436751576911352 1.0 1.0 147 P55011,P40855,P50542,O00170,P42858,Q9Y4P3,Q15056,Q9UQE7,O75381,Q9H3S7,O95202,P31749,Q96AY3,P51812,O95721,Q96AX1,Q969X5,Q99567,P42167,Q14739,P55795,Q9Y5Y5,Q8IY17,Q9UHX1,Q01082,Q96PZ0,Q8NCH0,Q9Y487,P98175,P25054,P61978,P09493,P49815,Q15437,P21281,Q71SY5,P35609,Q9UGU0,Q9UID3,Q06136,P02545,P16615,Q7LGA3,Q8N3R9 44 +Abnormality of the ischium 0.6033155713439972 0.6066836800586795 0.5440608547717682 1.0 1.0 3 Q8IZA0,Q14999 2 +Hyporeflexia of lower limbs 0.4368583800467869 0.6035845483583829 0.5461198883196401 1.0 1.0 9 Q9NR77 1 +Immunologic hypersensitivity 0.3663869787404141 0.6029685726398042 0.5465295963881005 1.0 1.0 33 Q5JRA6,Q9UID3,Q9NZ08,P21964,Q08J23,P00813,Q01082 7 +Heinz bodies 0.7333530630364048 0.601337716483233 0.547615073362699 1.0 1.0 2 O14936 1 +Extra axial cerebrospinal fluid accumulation 0.7330571174903853 0.6003541668755334 0.5482702263490424 1.0 1.0 2 Q03252 1 +Atrophy degeneration affecting the brainstem 0.4149044460447137 0.599983281277305 0.5485173777354935 1.0 1.0 11 O00429,O60313 2 +Abnormal ovarian morphology 0.3644631539424248 0.5995781511512009 0.5487874119047327 1.0 1.0 30 P31749,O75312,P31751,P78549,P02545,Q15437,Q03252,P16435,Q9Y4P3 9 +Prenatal maternal abnormality 0.4026837778296687 0.597337548049773 0.5502820404115738 1.0 1.0 12 Q14739,O43772,P16435 3 +Abnormal gastrointestinal motility 0.3611047622000202 0.5964905790461092 0.5508475456319957 1.0 1.0 26 P00403,P35637,P03886,P61978,Q01844 5 +Aplasia hypoplasia of the patella 0.4532537156962068 0.5953155662624398 0.5516325526677561 1.0 1.0 7 Q96AY3,O75419 2 +Small earlobe 0.4345934253138391 0.5924423611041085 0.5535544069644263 1.0 1.0 9 P21964,O00192,P98175,P10586 4 +Broad based gait 0.3604869273301185 0.5917634724715303 0.5540089864572992 1.0 1.0 26 Q00577,P98175,Q05086,Q03164,P42858,Q01082 6 +Cognitive impairment 0.3281857143318274 0.5893848919212827 0.5556031090142066 1.0 1.0 173 P40855,O60220,Q9Y287,Q9Y5P6,Q9UBB4,Q9Y4W6,Q08209,P03886,O60313,O43681,Q03164,P21964,P31483,Q9BQE5,P50542,Q10713,O95470,P42858,P42704,P00846,O75381,P31749,O00429,Q9NZ08,P56556,Q9H6K4,Q8N0X7,Q8IY17,Q01082,O43464,Q13501,Q9NPL8,Q9Y487,P00403,P49815,Q6PGP7,O95831,Q15437,Q99720,Q9Y2R0,P07196,Q6DKK2,P49770,P35637,P07602,Q9H9S5,Q9UEY8,O15020,Q96QK1 49 +Retinal dystrophy 0.3532389790598659 0.5887158062926957 0.5560519328779456 1.0 1.0 58 P00846,O75381,P40855,Q9Y287,Q15555,Q6P4Q7,Q15067,P03886,Q9H9S5,Q13868,Q10713,P38435,Q8IY17 13 +Subcutaneous hemorrhage 0.3652099584133864 0.5885660642325324 0.556152404345915 1.0 1.0 43 Q8NCH0,Q13126,Q969F9,Q9NWM8,P38435 5 +Proximal muscle weakness 0.3402351824398548 0.5863097045398064 0.557667410700825 1.0 1.0 66 Q8NI60,P00846,P35609,Q99720,P07196,Q13126,P35637,O60313,Q8TD16,Q9H9S5,P50402,Q8WXH0,Q9BPX6 13 +Venous thrombosis 0.3936353224135362 0.584866419756389 0.5586375394516185 1.0 1.0 14 Q9NZ08 1 +Clumsiness 0.3554981549263976 0.5848564620575883 0.5586442355377459 1.0 1.0 22 Q13501,P06753,Q9NR77,Q15067,Q05086,P07602,O43681,P42858 8 +Congenital contracture 0.3650009339938359 0.584708939376025 0.5587434422008575 1.0 1.0 42 P06753,Q96AY3,Q8NCH0,Q96A33,Q8TD16,Q15392,Q99567,Q9H9S5,O75844 9 +Abnormal biliary tract morphology 0.3551362338747463 0.5821510052572355 0.5604649717167263 1.0 1.0 22 P09601,Q14739,P02545,O43681,P07602,P50542,Q10713,P14174 8 +Extramedullary hematopoiesis 0.5224027224811425 0.5813571198441263 0.5609997909832201 1.0 1.0 4 Q14739 1 +Visual field defect 0.3613952822719896 0.5806172165277496 0.5614984662478204 1.0 1.0 49 P00846,O75381,P40855,O60220,Q9Y287,P31749,O00429,Q15555,P00403,P03886,Q8WWV3,O60313,Q9H6K4 13 +Abnormal placenta morphology 0.4412093779361743 0.5794059917319393 0.5623152621344705 1.0 1.0 8 Q6PGP7,O75844 2 +Abnormal morphology of the abdominal musculature 0.4109808369512087 0.5788563157518765 0.5626861282674094 1.0 1.0 11 Q8NCH0 1 +Neuropathic arthropathy 0.5945727326468487 0.5766172185380496 0.5641980649151161 1.0 1.0 3 O15269 1 +Fatigable weakness of respiratory muscles 0.3875360920229206 0.5760787571717608 0.5645619491891329 1.0 1.0 15 Q68CQ7,Q92804,Q15165,P35637 4 +Long fingers 0.3034548733194929 0.5755656962643466 0.5649087732380333 1.0 1.0 81 Q9P2J5,Q9UGU0,Q15125,Q8NCH0,Q15555,Q06136,Q2M1P5,Q03164,P21964,P42892,Q03252,P16435,O00170,Q96EK5,P55795,Q8IWS0,Q9UPP1,Q9UHX1 18 +Infantile spasms 0.3634510088788717 0.5740289374734442 0.565948219489631 1.0 1.0 35 P00846,Q13813,Q9H3S7,P03886,Q9UBX3,P49815 6 +Abnormal circulating lipid concentration 0.3116630750323069 0.573101211506651 0.5665761669937006 1.0 1.0 78 Q9BTV4,Q16836,P22830,P40855,P31751,Q9NVI7,Q15800,P49257,Q03252,P50542,P42858,O95470,Q8WXH0,Q9Y4P3,O75381,P28070,O43772,Q15125,Q15392,O43707,Q14739,Q9Y5Y5,O75845,Q8N511,Q13045,O75880,P07602,P02545,O75844,P50402,Q10471,Q9Y6B6 32 +Attenuation of retinal blood vessels 0.4480776938047174 0.5720694947227019 0.5672748946857602 1.0 1.0 7 P38435 1 +Duplication of hand bones 0.340690667330368 0.5718684054291229 0.5674111299754818 1.0 1.0 65 Q7Z4L5,Q8WVQ1,Q15125,Q14739,O75845,Q15067,P98175,Q2M1P5,O60826,P46783,Q8WXW3,P21964,Q8NCM8,Q9BXW9,Q10713,Q9UPP1,Q8IY17,Q9UHX1 18 +Lagopthalmos 0.5925992989574587 0.5698975277344971 0.5687472017956567 1.0 1.0 3 O75844 1 +Dysgenesis of the hippocampus 0.5923623445825978 0.5690923873988392 0.5692934442692483 1.0 1.0 3 Q9BPU6,Q8TAB3 2 +Vascular skin abnormality 0.3020775884140897 0.5662569052123988 0.5712191512718698 1.0 1.0 129 P00846,O95155,Q9Y3Z3,Q15125,P31749,Q8NCH0,Q13126,Q9Y487,Q86YV9,Q06136,P03886,Q969F9,O75844,Q9NWM8,P51648,P38435 16 +Abnormal thalamic mri signal intensity 0.4374192913671545 0.5617250634864601 0.574303355167378 1.0 1.0 8 Q96EY7,Q9GZY8,P31749 3 +Hypomelanotic macule 0.7203314590115457 0.5586061871365009 0.5764305165316084 1.0 1.0 2 P49815 1 +Neoplasm of the oral cavity 0.3845950087401245 0.5580461999330055 0.5768128367409155 1.0 1.0 15 P31749,P25054,Q2M1P5,P02545,Q969G3,Q8NCM8 6 +Squamous cell carcinoma of the skin 0.5160264849848761 0.5577427808061849 0.5770200400788641 1.0 1.0 4 P02545,P18074 2 +Clonus 0.359457395950626 0.5558378587925707 0.5783217020443128 1.0 1.0 31 Q99720,O75298,O60220,Q9Y5P6,P35637,P07602,Q9H9S5,P42858,Q01433,Q8N0X7,Q01082 11 +Redundant skin 0.3563793789772697 0.5538270952344048 0.5796971830903459 1.0 1.0 27 Q8NCH0,Q9Y487,P38435 3 +Abnormal vascular physiology 0.3531485524753068 0.5535322023743485 0.5798990361837038 1.0 1.0 55 Q9Y3Z3,P31749,Q9NZ08,P00403,P03886,O75844,O96000,Q9NWM8 8 +Abnormally ossified vertebrae 0.5875924998936434 0.5529643873063027 0.5802877963371889 1.0 1.0 3 Q14739 1 +Absent or minimally ossified vertebral bodies 0.5875924998936434 0.5529643873063027 0.5802877963371889 1.0 1.0 3 Q14739 1 +Stenosis of the external auditory canal 0.4355134536452556 0.5528770347069428 0.5803476139882067 1.0 1.0 8 P55011,P16435 2 +Syringomyelia 0.5873297809354758 0.5520805238885068 0.5808931849812804 1.0 1.0 3 P35222,O60341 2 +Young adult onset 0.4161983333817219 0.5503970311052527 0.5820470845588155 1.0 1.0 10 Q14566,P02545,P07602,P31483,P38435 5 +Abnormal bleeding 0.2900516806860991 0.5492725835856216 0.5828183993296039 1.0 1.0 111 P12814,P16930,P31749,Q8NCH0,Q13126,Q9Y487,Q9NZ08,P25054,Q86YV9,O60333,Q969F9,O75844,P35579,P06132,Q9NWM8,P49815,P38435,Q9UHX1 18 +Chordee 0.4429306412590074 0.5491528576271204 0.5829005534329568 1.0 1.0 7 P49589,P53701,O60341,P16435 4 +Lower extremity joint dislocation 0.2893125371243763 0.5489903997512939 0.5830120381553205 1.0 1.0 85 P55011,Q9Y5P6,Q9NX62,Q96A33,P21964,Q9Y4P3,Q15056,Q9UQE7,O95202,P31749,Q15125,Q8TD16,Q9UHX1,Q9Y487,P25054,Q8WVQ1,P06753,Q9NQX3,P02545,Q9H9S5,O75844,Q9BXW9 22 +Asthma 0.3503809011019388 0.5467657335089606 0.584539687558161 1.0 1.0 22 Q5JRA6,Q9UID3,P21964,Q08J23,P00813 5 +Abnormality of the alveolar ridges 0.434045852826711 0.5460837131099783 0.5850083947329057 1.0 1.0 8 Q15392,P98175,Q2M1P5 3 +Abnormal nephron morphology 0.3362346580732372 0.5441373218893255 0.5863469793504725 1.0 1.0 66 P00846,O60333,Q9NZ08,P00403,Q14C86,P03886,Q8N1F7,O95470,P00813 9 +Abnormal facial expression 0.3589106797294158 0.5436228578626622 0.586701026996479 1.0 1.0 33 Q06787,Q14203,Q9Y5P6,Q00577,P06753,Q9NR77,Q05086,Q969X5,Q9H9S5,P50570,Q96QK1 11 +Supernumerary nipple 0.3931257648178514 0.5435465729923833 0.5867535337133516 1.0 1.0 12 Q7LGA3,Q8IY17,P61978 3 +Abnormality of metacarpophalangeal joint 0.5845512799735351 0.5427618835180807 0.5872937601813473 1.0 1.0 3 P16435 1 +High hypermetropia 0.3901369999092712 0.5425232950095297 0.58745806420302 1.0 1.0 13 O95155,Q9Y4P3,Q15056,Q71SY5,O15294 5 +Broad toe 0.3585857970588806 0.5410614274274139 0.5884652437404301 1.0 1.0 33 P55011,Q9H3S7,Q96PZ0,Q15125,Q7LGA3,P42858,O60826,Q8N3R9,Q9UHX1 9 +Dry skin 0.3545171072625713 0.5396540271942529 0.589435650018705 1.0 1.0 27 Q9Y3Z3,Q06136,Q6PGP7,P51648,P00813 5 +Hypertriglyceridemia 0.3494175202214397 0.539635469951727 0.5894484502157575 1.0 1.0 22 O95470,P28070,P50402,P31751 4 +Cardiac valve calcification 0.5110243436140685 0.5394165515375937 0.5895994628660395 1.0 1.0 4 P02545,O75844 2 +Mitral valve calcification 0.5110243436140685 0.5394165515375937 0.5895994628660395 1.0 1.0 4 P02545,O75844 2 +Dysphagia 0.3059080393219487 0.5378004758251789 0.5907148034506746 1.0 1.0 139 O95155,O60220,Q08209,Q9Y4W6,P03886,O60313,Q03164,Q96D71,P42858,P42704,P00846,O00429,Q9NR77,P56556,Q01105,Q14739,Q15233,Q9UHX1,Q05086,Q99720,P06753,Q15067,Q9P0J1,Q9GZY8,P35637 25 +Abnormal mitochondrial number 0.7138206569991161 0.5376770107216827 0.5908000532465938 1.0 1.0 2 P46976 1 +Narrow iliac wing 0.5104423280848187 0.5372960391396909 0.5910631409751499 1.0 1.0 4 P50542 1 +Abnormal femoral neck head morphology 0.3576216167336968 0.536713276004315 0.5914656841887784 1.0 1.0 47 Q7RTS9,Q8WVQ1,Q96AY3,Q9Y487,Q96A33,O75718,O75844,Q7LGA3,Q14739,O95831,Q96HY6 11 +Hydranencephaly 0.5825867904233644 0.5362057565877273 0.5918163554485913 1.0 1.0 3 Q53EZ4 1 +Abnormal circulating proline concentration 0.4750454514459444 0.5333943488461875 0.5937606285832913 1.0 1.0 5 Q9P0J1,O96000,P20674 3 +Irregular capital femoral epiphysis 0.712044983722999 0.5320219731581591 0.5947107769944318 1.0 1.0 2 P50542 1 +Repetitive compulsive behavior 0.5087163234013883 0.531022319441363 0.5954033126031599 1.0 1.0 4 P49815 1 +Prelingual sensorineural hearing impairment 0.7114530926309599 0.5301420968012724 0.5960134137512418 1.0 1.0 2 O60220 1 +Childhood onset sensorineural hearing impairment 0.7114530926309599 0.5301420968012724 0.5960134137512418 1.0 1.0 2 O60220 1 +Cervical spinal canal stenosis 0.7114530926309596 0.5301420968012712 0.5960134137512427 1.0 1.0 2 Q8IWS0 1 +Abnormal pyramidal sign 0.2953689848045188 0.5296699655688518 0.5963407753679786 1.0 1.0 122 Q8NI60,O60220,O60313,P42858,P51648,P00846,O00429,Q9NR77,Q9NZ08,Q9H6K4,Q8IY17,Q9Y3Z3,O95831,Q99720,O75298,Q6DKK2,P07196,Q15067,P35637,Q9H9S5 20 +Occipital meningocele 0.4382102762564082 0.5283222488340812 0.5972756919274649 1.0 1.0 7 Q10713,O00192,P21964 3 +Shallow acetabular fossae 0.7105652559929012 0.5273271305780494 0.5979664369420874 1.0 1.0 2 Q9NUQ7 1 +Cloverleaf skull 0.7105652559929012 0.5273271305780494 0.5979664369420874 1.0 1.0 2 P16435 1 +Abnormality of the proximal phalanx of the thumb 0.710565255992901 0.5273271305780475 0.5979664369420887 1.0 1.0 2 Q15233 1 +Oral pharyngeal dysphagia 0.3874671778048896 0.5272454313970834 0.5980231632003952 1.0 1.0 13 Q01105,P42858 2 +Osteomyelitis 0.3869561105200072 0.5243293772735921 0.6000494674529375 1.0 1.0 13 Q13126 1 +Abnormality of fibula morphology 0.3895708138746953 0.5237585417591647 0.6004464922358097 1.0 1.0 12 Q96HY6,Q8NCM8,P16435 3 +Leiomyosarcoma 0.4203580013615415 0.5233453516240216 0.6007339463326768 1.0 1.0 9 P31749 1 +Bilateral cleft palate 0.5785666760810639 0.522875056313566 0.6010612038302681 1.0 1.0 3 O15111 1 +Non midline cleft palate 0.5785666760810639 0.522875056313566 0.6010612038302681 1.0 1.0 3 O15111 1 +Decreased facial expression 0.3512839808488073 0.5219553790714424 0.6017013986760826 1.0 1.0 26 Q06787,Q14203,Q9Y5P6,Q00577,P06753,Q05086,Q969X5,Q9H9S5,Q96QK1 9 +Coronal craniosynostosis 0.4367230407676398 0.5217978784089555 0.6018110670142154 1.0 1.0 7 Q9NX62 1 +Abnormality of the thyroid gland 0.2899612405700307 0.5215044034510699 0.6020154388382397 1.0 1.0 114 O95155,Q9Y3Z3,P31749,O00429,Q13423,P25054,P00403,P03886,O60313,P61978,Q13868,O95470,P49815,P00813 14 +Glaucoma 0.2790227445027016 0.5165187953500395 0.6054921151432779 1.0 1.0 97 P40855,Q9Y5P6,P21964,P50542,O75381,Q15125,P31749,Q53H12,Q86XL3,Q9Y3Z3,Q8NCH0,Q13868,O60826,Q6PGP7,Q8WVQ1,Q15555,Q06136,P46783,Q9H9S5 19 +Hypointensity of cerebral white matter on mri 0.4426335060765907 0.5164852155680938 0.6055155622157202 1.0 1.0 6 Q9Y3Z3 1 +Mixed hearing impairment 0.4354987308214589 0.5164412742775527 0.6055462448225932 1.0 1.0 7 Q9NWM8 1 +Abnormal renal medulla morphology 0.4094523059480666 0.5163882240024765 0.605583288830212 1.0 1.0 10 Q7Z4L5 1 +Mitral stenosis 0.5765947254721013 0.5163790145013819 0.6055897197546991 1.0 1.0 3 O75844 1 +Aortic valve calcification 0.5765947254721013 0.5163790145013819 0.6055897197546991 1.0 1.0 3 O75844 1 +Macrodontia of permanent maxillary central incisor 0.707013909440667 0.5161260613192726 0.6057663669902891 1.0 1.0 2 P21281 1 +Vocal cord paralysis 0.3597381065450835 0.5158311960697419 0.6059723121962226 1.0 1.0 18 Q8WXH0,Q9NR77,P50402 3 +Abnormal renal pelvis morphology 0.3427529784224649 0.5127063869454828 0.6081567212897578 1.0 1.0 60 O95155,P40855,Q08209,P50542,Q5JRA6,O75381,Q15125,Q8N0X7,Q9Y5Y5,Q8NCH0,P98175,P25054,P61978,Q08J23,P16435,Q8NCM8,O60826,Q71SY5,O75718 19 +Biliary tract abnormality 0.349024039309355 0.5122881652196988 0.6084493467941041 1.0 1.0 25 P09601,O95202,Q14739,P02545,O43681,P07602,P50542,Q10713,P14174 9 +Abnormal head movements 0.3981863921173412 0.5109029112133274 0.6094190425716155 1.0 1.0 11 Q99720,P35637 2 +Congenital malformation of the right heart 0.4257830214393467 0.50818067522731 0.6113266419765933 1.0 1.0 8 P40855,P21281,O15460 3 +Focal white matter lesions 0.4254682118810781 0.5067486672983621 0.612331178227493 1.0 1.0 8 Q9P0J1 1 +Myopia 0.288302793817883 0.5064781659446365 0.6125210135876353 1.0 1.0 113 O60220,Q9Y5P6,Q9NVI7,P30533,P42858,P51648,Q9UQE7,P31749,Q53H12,Q9NWM8,Q15233,Q9UHX1,Q00577,Q8NCH0,O75419,P98175,Q9Y487,Q13555,Q05086,Q08J23,Q13868,Q969G3,P61978,Q15437,P21281,Q13045,Q8WVQ1,Q9UGU0,Q15555,Q15067,Q9H9S5,Q9H3H1 32 +Hashimoto thyroiditis 0.703758508434452 0.5059423810717696 0.6128970992496205 1.0 1.0 2 Q15437 1 +Red green dyschromatopsia 0.5730910095085138 0.5049083998493179 0.6136231740906477 1.0 1.0 3 O60313 1 +Abnormal blood transition element cation concentration 0.3967327157589418 0.5032822894228757 0.6147658164377727 1.0 1.0 11 Q9Y487 1 +Neurodegeneration 0.3505492364612929 0.5032628911867791 0.6147794529257058 1.0 1.0 28 Q92804,Q6DKK2,Q15165,Q9Y3Z3,Q68CQ7,P35637,P42858,Q01082 8 +Stillbirth 0.3967245096161901 0.5032393325661442 0.6147960142417439 1.0 1.0 11 O75844,P16435 2 +Babinski sign 0.2887889520621339 0.5003623930604479 0.6168199285118208 1.0 1.0 84 P00846,Q99720,O75298,Q6DKK2,P07196,O60220,Q9NR77,Q15067,P35637,O60313,P42858,O95831,Q9H6K4,Q8IY17 14 +Subcortical heterotopia 0.5001561089923156 0.500245468389254 0.61690224624273 1.0 1.0 4 P07942 1 +Subcortical band heterotopia 0.5001561089923156 0.500245468389254 0.61690224624273 1.0 1.0 4 P07942 1 +Cranial asymmetry 0.438577836620181 0.499576533212752 0.6173732849578437 1.0 1.0 6 P40855 1 +Proximal muscle weakness in lower limbs 0.3639210253595611 0.4989770160248877 0.6177955759501645 1.0 1.0 17 P07196,P02545,P50402,P50570,Q8WXH0 5 +Abnormality of femur morphology 0.3262443269144124 0.4986477964972958 0.6180275270379689 1.0 1.0 69 Q7RTS9,Q8WVQ1,Q96AY3,Q9Y487,Q32P28,Q96A33,O00116,O75718,O75844,Q7LGA3,P16435,Q8NCM8,Q14739,O95831,Q96HY6,Q9UHX1 16 +Prominent metopic ridge 0.3823967866282744 0.4984408345395557 0.6181733612476115 1.0 1.0 13 Q9H0W8,P61978,Q00577 3 +Abnormality of skin pigmentation 0.304207682400868 0.4972445864720988 0.6190165832299397 1.0 1.0 141 P55011,Q13423,P03886,P21964,P06132,O00170,P42858,P51648,Q9H3S7,Q15125,P31749,O75312,Q96AY3,O60333,Q969F9,Q14739,Q01082,Q96PZ0,P25054,Q05086,P00403,Q08J23,P49815,Q6PGP7,Q15437,P33991,Q9UGU0,Q86YV9,Q15555,Q06136,P07602,P16615,O75844,Q7LGA3,Q8N3R9 35 +Hyperpigmentation of the skin 0.2775184452830322 0.494827571723812 0.62072184012598 1.0 1.0 97 P55011,Q13423,P06132,O00170,P42858,P51648,Q9H3S7,P31749,O60333,Q14739,Q96PZ0,P25054,P49815,Q6PGP7,Q15437,P33991,Q9UGU0,Q15555,Q06136,P16615,O75844,Q7LGA3,Q8N3R9 23 +Aortic valve stenosis 0.4141560871248403 0.4938022370698877 0.6214458531142462 1.0 1.0 9 O60826,O75844,Q15125 3 +Optic nerve dysplasia 0.6996152707901787 0.493100107674039 0.6219418547941733 1.0 1.0 2 P50542 1 +Abnormality of carpal bone ossification 0.4363917203378812 0.4905228206362324 0.6237639854189563 1.0 1.0 6 Q8WVQ1,Q9NUQ7,Q15125 3 +Femoral bowing 0.394285173672449 0.4905016977606842 0.623778928734986 1.0 1.0 11 Q7RTS9,Q32P28,P16435 3 +Clonic seizure 0.4217358578068279 0.489842036587942 0.6242456819789282 1.0 1.0 8 P07602,Q8TAB3,O14936,Q01082 4 +Calcification of cartilage 0.6984314886061006 0.489455742311174 0.624519080380888 1.0 1.0 2 P50542 1 +Bowel diverticulosis 0.4126855634949982 0.4868523051310632 0.6263630005300111 1.0 1.0 9 P43246,Q9Y4P3,P31749 3 +Eruption failure 0.4209393618854069 0.4862514362054634 0.6267889067117491 1.0 1.0 8 P25054 1 +Abnormal aortic arch morphology 0.3725412777648209 0.4851454746415887 0.6275731564730602 1.0 1.0 15 Q9H0W8,Q96DF8,Q9UHX1 3 +Relative macrocephaly 0.3525962952851582 0.4830095876231528 0.6290889286539183 1.0 1.0 37 P55011,Q9H3S7,Q96PZ0,P25054,Q15392,O75844,Q7LGA3,Q8N3R9,P42858,Q15233 10 +Short digit 0.3148217385295129 0.4824814600914285 0.6294639656997356 1.0 1.0 162 P55011,P48449,Q7RTS9,O95155,Q08209,Q9NX62,Q2M1P5,Q03164,Q03252,P42858,Q9NZN8,Q9UQE7,Q5JRA6,Q9H3S7,P31749,Q14739,P00813,Q8N0X7,Q8IY17,Q9UHX1,Q96PZ0,Q13555,P25054,Q08J23,Q13868,P16435,Q8NCM8,O60826,P13073,Q15437,Q8IWS0,O95831,P38435,Q7Z4L5,Q8WVQ1,Q9UGU0,Q06136,P46783,O75844,Q7LGA3,Q9BXW9,Q8N3R9 42 +Knee flexion contracture 0.3468601310201967 0.4819371834206585 0.6298505706713113 1.0 1.0 27 Q96AY3,Q8TD16,Q86XL3,Q7LGA3 4 +Finger clinodactyly 0.273977169546852 0.4805608770639792 0.6308286266524274 1.0 1.0 93 O95155,Q7RTS9,Q2M1P5,Q03164,Q03252,Q9Y4P3,Q9UQE7,Q9NZN8,Q5JRA6,Q8NFH4,Q15125,P31749,Q15233,Q8IY17,Q9UHX1,O15294,O75419,Q05086,Q08J23,P21281,Q13045,Q8WVQ1,Q9UGU0,P02545,Q9BXW9 25 +Abnormality of thalamus morphology 0.3466101595084249 0.4777208412119469 0.632848908606781 1.0 1.0 19 Q9Y5P6,P31749,Q9GZY8,Q96EY7,Q9H9S5 5 +Mixed hypo and hyperpigmentation of the skin 0.5640666349014127 0.4757999519782365 0.6342169040826173 1.0 1.0 3 P02545 1 +Spinal deformities 0.4325616928629804 0.4747669594931774 0.6349530855339736 1.0 1.0 6 Q9H9S5,Q9Y5P6 2 +Abnormality of circulating glucocorticoid level 0.374657629188831 0.473348565708903 0.6359645186933887 1.0 1.0 14 Q13423,P31749 2 +Perimembranous ventricular septal defect 0.4174622279423463 0.4706502629717244 0.6378905077809278 1.0 1.0 8 Q9UHX1 1 +Corticospinal tract hypoplasia 0.6922166321396905 0.4705082022387156 0.6379919755196677 1.0 1.0 2 Q13045 1 +Abnormal length of corpus callosum 0.6922166321396905 0.4705082022387156 0.6379919755196677 1.0 1.0 2 P48449 1 +Complex febrile seizure 0.6901450133175537 0.4642628301793105 0.642459451027652 1.0 1.0 2 Q8TAB3 1 +Reduced visual acuity 0.2935205859126496 0.4608701753986902 0.6448917505653038 1.0 1.0 127 O60220,Q9Y4W6,Q9BV73,P30533,P03886,Q8WWV3,O43681,O60313,P06132,O00170,Q10713,Q86Y39,P00846,P31749,O00429,Q9NZ08,Q13277,P56556,O43676,Q9H6K4,Q9UHX1,O15294,Q9NPL8,Q96S66,P25054,O96000,Q71SY5,Q86YV9,Q15555,Q9H9S5,Q15058 31 +Excessive daytime somnolence 0.3579430429520533 0.4608203807369132 0.6449274782992052 1.0 1.0 17 Q9H9S5,P42858,P31749 3 +Abnormality of the nasal tip 0.2838792588353279 0.4607460538950631 0.6449808094290392 1.0 1.0 111 Q13409,Q2M1P5,Q96A33,Q03164,P21964,P42892,Q96EK5,Q9UQE7,Q9BSJ2,P10586,Q06787,P38159,Q96DF8,Q01082,Q9UHX1,Q00577,O75845,Q9Y487,P25054,P61978,Q13868,Q969G3,P16435,O95831,P21281,Q71SY5,Q9UGU0,O43292,P02545,O75844,Q7LGA3,Q14696,Q9UPP1 33 +Abnormal lower limb bone morphology 0.3267954049939129 0.4605115185460127 0.6451491056294993 1.0 1.0 188 P55011,O95155,Q7RTS9,Q9NX62,Q2M1P5,Q96A33,Q03164,P21964,Q03252,P50542,P42858,Q10713,Q9UQE7,Q5JRA6,Q9H3S7,Q15125,P31749,Q96AY3,Q32P28,Q15392,Q8WXW3,Q99567,Q14739,P00813,Q8N0X7,Q9UHX1,Q96PZ0,O75845,O75419,P98175,Q9Y487,Q13555,P25054,Q08J23,P16435,Q8NCM8,P13073,Q8IWS0,O95831,Q71SY5,Q96HY6,Q7Z4L5,Q8WVQ1,Q9UGU0,P07602,O00116,Q9H9S5,O75844,Q7LGA3,O75718,Q9BXW9,Q15058,Q8N3R9 53 +Decreased circulating gonadotropin concentration 0.45599916057193 0.4603573658856747 0.6452597312952153 1.0 1.0 5 P31749 1 +Decreased activity of mitochondrial complex i 0.3497901378650268 0.4578738518282783 0.6470430737539079 1.0 1.0 39 O43676,Q70HW3,P03886 3 +Incomplete penetrance 0.3465468611816353 0.4562963857876072 0.648176862560411 1.0 1.0 31 P00846,O60333,P03886,O60313,O43707 5 +Corneal dystrophy 0.4874691988783616 0.4557387032757196 0.648577887036059 1.0 1.0 4 Q13868 1 +Increased total bilirubin 0.4868226236304284 0.4535081026284187 0.6501829101559613 1.0 1.0 4 P14314,P23786,Q9UGP8 3 +Short palpebral fissure 0.3445207849336515 0.4518422042428314 0.6513826631616157 1.0 1.0 29 Q03164,Q13868,Q9UHX1 3 +Bone spicule pigmentation of the retina 0.4127575320174856 0.4497392286447713 0.6528984818157364 1.0 1.0 8 Q15555,Q96S66 2 +Tall stature 0.3375309738766993 0.4494521639307545 0.6531055085993382 1.0 1.0 59 P55011,Q9UGU0,O00170,Q9H3S7,Q96PZ0,P31749,Q8NCH0,P06753,Q13423,Q2M1P5,Q8N3R9,P61978,Q7LGA3,P16435,P42858,Q9NWM8,Q15233 17 +Decreased specific antibody response to vaccination 0.6848179934892022 0.4483692773853694 0.6538867105318114 1.0 1.0 2 P17812 1 +Weakness due to upper motor neuron dysfunction 0.3001435749379452 0.4477270436303361 0.6543502017315963 1.0 1.0 140 O95155,Q7RTS9,Q5MNZ6,Q9H0B6,Q9Y4W6,Q13423,P03886,O60313,P00846,P31749,O00429,Q9NZ08,Q9H6K4,Q8IY17,Q9Y3Z3,P00403,P49815,O95831,O75298,Q6DKK2,P35637,Q9H9S5,Q9UBX3 23 +Portal fibrosis 0.484749777909376 0.4463827105150834 0.6553208196515208 1.0 1.0 4 P55263,P06737,Q9H3U1 3 +Abnormality of the metaphysis 0.3394940324745134 0.4458413282146036 0.6557118661031995 1.0 1.0 57 Q7Z4L5,Q7RTS9,Q13126,Q9HC07,O95831,P00813 6 +Lewy bodies 0.4253765798448327 0.4455908880029812 0.6558927937910186 1.0 1.0 6 P31483,Q96QK1 2 +Abnormal protein glycosylation 0.3554910857891679 0.445325133604678 0.6560848071202918 1.0 1.0 17 Q9Y487 1 +Hyperextensibility of the knee 0.6833382657591045 0.4439975102899745 0.6570443839491926 1.0 1.0 2 Q8WVQ1 1 +Genu recurvatum 0.6833382657591045 0.4439975102899745 0.6570443839491926 1.0 1.0 2 Q8WVQ1 1 +Atrial arrhythmia 0.3947134754134496 0.4436789800288637 0.6572746948023442 1.0 1.0 10 P35609,P02545,P50402 3 +Constipation 0.2782207246445904 0.4417988678608274 0.6586347578951823 1.0 1.0 104 O43464,O95155,Q8NCH0,Q9UID3,Q13423,P25054,Q05086,P00403,P03886,P78318,Q03164,Q7LGA3,P61978,P16435 14 +Abnormal glycosylation 0.3346515493569725 0.441465765822789 0.6588758400955195 1.0 1.0 21 Q2TAA5,Q9Y487,Q9BT22,P46977,Q8N511,Q05682,Q10471 7 +Down sloping shoulders 0.3404125116991778 0.4411978507392154 0.6590697690427159 1.0 1.0 26 P55011,Q9UGU0,Q9H3S7,Q96PZ0,P02545,Q7LGA3,P42858,Q9Y4P3,Q8N3R9 9 +Bradykinesia 0.3382866839696292 0.4411662597684936 0.6590926375145811 1.0 1.0 24 O43464,Q06787,Q6DKK2,Q14203,Q9BSH4,P06753,Q04637,P42858,Q96QK1 9 +Abnormal epidermal morphology 0.336679425959291 0.4379445330614626 0.6614264922312425 1.0 1.0 23 P16615,O75844,Q06136,P31749 4 +Abnormal metabolic brain imaging by mrs 0.3597710387819519 0.4374573410455074 0.6617797068696127 1.0 1.0 16 O00429,P03886 2 +Abnormality of chromosome segregation 0.4497142249452018 0.436975713545268 0.662128961231675 1.0 1.0 5 Q14739 1 +Lymphedema 0.3596362429075478 0.4366403807515276 0.662372172738058 1.0 1.0 16 Q14739,P49815,P31749 3 +Abnormality of temperature regulation 0.277844962438393 0.4364454611535289 0.6625135611702122 1.0 1.0 104 P03886,P00846,O43772,P28070,O60333,Q9NR77,Q9NZ08,Q9HC07,Q8N1F7,O43707,Q14739,P00813,Q01082,Q9Y3Z3,Q2TAA5,P00403,Q05086,P61978,P49815,Q14C86 20 +Neurogenic bladder 0.4228148148148168 0.4353147908499634 0.6633339503087818 1.0 1.0 6 P83436,Q8N5K1,O76024,P56589,P50336 5 +Abnormality of the elbow 0.3237455653811345 0.4322784131966762 0.6655390745070484 1.0 1.0 67 Q7RTS9,Q96AY3,P25054,Q03164,Q7LGA3,P50402,P16435,Q8WXH0,Q9H6K4 9 +Prolonged partial thromboplastin time 0.4212129855921087 0.4289243634119677 0.6679782693303626 1.0 1.0 6 P38435 1 +Abnormal circulating progesterone level 0.4207924708306929 0.4272512755155708 0.66919631774809 1.0 1.0 6 P16435 1 +Decreased circulating progesterone 0.4207924708306929 0.4272512755155708 0.66919631774809 1.0 1.0 6 P16435 1 +Keratitis 0.3818860697344008 0.4268037535198363 0.669522272339151 1.0 1.0 11 Q9NZ08,P06132 2 +Cerebral amyloid angiopathy 0.676827463746675 0.4249897394439905 0.6708441545351351 1.0 1.0 2 Q9Y287 1 +Glucose intolerance 0.2776193088500894 0.4243834436834682 0.6712861931335306 1.0 1.0 105 P00846,Q9Y6M1,Q9Y3Z3,P31751,O00429,Q06136,P00403,P03886,O60313,O75844,P43304,O43676,Q86Y39,Q8IY17 14 +Abnormal peripheral nervous system physiology 0.3371260638026276 0.4237248696294697 0.6717664757150223 1.0 1.0 57 Q9NSV4,Q99720,O60220,P07196,Q15125,Q7Z406,Q9UBB4,O60333,Q9NR77,O95721,Q9GZY8,O60313,O43681,P07602,P50570,O95831,Q71SY5 17 +Distal arthrogryposis 0.4454537986814221 0.4213478808029916 0.6735010715661982 1.0 1.0 5 Q8NCH0 1 +Arthralgia 0.3439998878026263 0.4205287657218917 0.674099219842264 1.0 1.0 35 P28070,Q9NZ08,Q2M1P5,P25054,Q15800,P02545,Q03252,O00170,Q9Y4P3,Q15056,Q96HY6,P14174 12 +Nephrotic syndrome 0.3409744001481877 0.419600027835852 0.6747776680356194 1.0 1.0 30 Q8NCH0,Q9BT22,O95721,Q8N1F7,O95470,P00813 6 +Psoriasiform dermatitis 0.4449052132701283 0.4193490655459153 0.6749610427879933 1.0 1.0 5 P10321,P00533,Q15800,P78536 4 +Decreased calvarial ossification 0.4767140200010251 0.4191401981555585 0.6751136740819881 1.0 1.0 4 O75718,O75844 2 +Dementia 0.3342805979399487 0.4184748338699668 0.6755999827068635 1.0 1.0 59 P00846,O43464,Q13501,O60220,Q9Y287,Q9UBB4,O00429,Q9Y487,P00403,P03886,O60313,O43681,P35637,P07602,P42858,Q96QK1,Q8IY17 17 +Hypocholesterolemia 0.4049923258923128 0.4157548191478268 0.6775894229142003 1.0 1.0 8 P07602,Q9NVI7,Q15800 3 +Skin rash 0.3445237929950525 0.4156009202541014 0.6777020531781321 1.0 1.0 18 Q14739,P28070,Q06136 3 +Limited hip movement 0.360518612876873 0.4143153981431578 0.6786431383807427 1.0 1.0 15 Q96AY3,Q8TD16,O75844,Q7LGA3 4 +Bird like facies 0.4172361405078728 0.4131786778065764 0.6794757087904015 1.0 1.0 6 P02545,P18074,O75844 3 +Abnormal erythrocyte enzyme level 0.3317676118169333 0.4117173947044554 0.6805465738288994 1.0 1.0 22 P00813 1 +Keratoconjunctivitis 0.3875013022406208 0.4090069020334294 0.6825345960030607 1.0 1.0 10 Q9NZ08,P06132 2 +Abnormal lower motor neuron morphology 0.3956499079023952 0.4080466572842802 0.6832394211471613 1.0 1.0 9 Q99720,P35637 2 +Fatigue 0.2927588943150022 0.4061747446142483 0.6846142093575969 1.0 1.0 80 Q92804,Q70HW3,Q15165,P06753,Q4J6C6,O00429,Q13423,Q9NZ08,O60333,Q68CQ7,P35637,O60313,Q14739,P49815,Q01082 15 +Dilatation of the cerebral artery 0.3950962016703797 0.405542238610198 0.6850789770938872 1.0 1.0 9 P38435 1 +Abnormality of the vestibulocochlear nerve 0.5411486086441828 0.404942647348813 0.6855196690451215 1.0 1.0 3 P35240,P10644 2 +Neoplasm of the inner ear 0.5411486086441828 0.404942647348813 0.6855196690451215 1.0 1.0 3 P35240,P10644 2 +Abnormality of earlobe 0.3362856678051286 0.4039321339655589 0.6862626256154514 1.0 1.0 27 P98175,Q15392,P21964,Q7LGA3,P16435,P10586 6 +Increased circulating acth level 0.4720478396632373 0.4036093226267832 0.6865000291344883 1.0 1.0 4 P16435 1 +Esophageal atresia 0.4146775820329421 0.4031411572916648 0.686844384568136 1.0 1.0 6 Q8NCM8 1 +Abnormality of the musculature of the upper limbs 0.2974566171880785 0.4009157166828082 0.6884821781592558 1.0 1.0 78 Q9Y5P6,O60313,P31483,P46976,P50570,Q8WXH0,O00429,Q9NR77,Q9BQT8,Q8TB36,Q8TD16,O14979,Q13501,Q14203,Q9Y487,P07196,P06753,P46783,P07602,P02545,Q9H9S5,P50402 22 +Autoamputation 0.4139259259259291 0.4002064396290515 0.6890044719558235 1.0 1.0 6 O15269,Q9H4A3,Q12756,O15270,P48643 5 +Abnormality of amino acid metabolism 0.6673572062740502 0.398025495647147 0.6906113922802759 1.0 1.0 2 P18074 1 +Flat nasal alae 0.6673572062740502 0.398025495647147 0.6906113922802759 1.0 1.0 2 P18074 1 +Cutaneous melanoma 0.6673572062740503 0.3980254956471464 0.6906113922802763 1.0 1.0 2 P11802 1 +Abnormality of dental color 0.53834711473788 0.3966063590051545 0.6916577625524987 1.0 1.0 3 Q6P4Q7 1 +Myoclonus 0.2730962091400428 0.3956312346987748 0.6923770913272778 1.0 1.0 101 Q8NI60,Q13813,Q9Y4G8,Q08209,Q9Y4W6,P03886,Q03252,P42858,Q10713,P00846,P31749,O60333,Q96EY7,Q01105,Q9NPL8,Q00577,P00403,Q05086,P00374,P13073,Q9UBX3 21 +Hypoplastic pelvis 0.5378922439313351 0.3952598701305156 0.6926511122034584 1.0 1.0 3 Q14999,Q9H0W5 2 +Abnormal larynx physiology 0.3521936726026848 0.3919891540552365 0.6950662276420618 1.0 1.0 16 Q68CQ7,Q92804,Q15165,P35637 4 +Entropion 0.3914169163576577 0.3889996894161314 0.6972763761379173 1.0 1.0 9 P02545,P18074,O75844,P30153 4 +Speech apraxia 0.3351191176094373 0.3886648333091246 0.6975240999062151 1.0 1.0 28 P55011,Q9H3S7,Q96PZ0,Q00577,Q8N3R9,Q7LGA3,P42858,Q15233,Q8N0X7 9 +Bowing of the arm 0.4346900299959737 0.3827152532170305 0.7019309035592365 1.0 1.0 5 Q32P28 1 +Facial diplegia 0.3729667765456175 0.3821911630178721 0.7023195761089807 1.0 1.0 11 Q9H9S5 1 +Abnormality of the intrinsic pathway 0.3727333013520139 0.3810382819448794 0.7031748425703161 1.0 1.0 11 Q9Y487 1 +Frontotemporal dementia 0.3727032887816484 0.380890139741124 0.7032847693417912 1.0 1.0 11 Q13501,P31483,Q14203,P35637 4 +Focal t2 hyperintense basal ganglia lesion 0.3259609954320732 0.3802926129750629 0.7037282183486813 1.0 1.0 21 P03886 1 +Abnormal left ventricle morphology 0.3369698268699868 0.3793620656652766 0.7044190161274542 1.0 1.0 32 P35609,O75880,P00403,O75208,P03886,Q9H9S5,O00170,Q15233 8 +Broad thumb 0.3374476091845368 0.3783128718781217 0.7051981843899897 1.0 1.0 33 P55011,Q9H3S7,Q96PZ0,Q08J23,Q13868,Q7LGA3,P42858,Q8N3R9,Q9UHX1 9 +Thin clavicles 0.5317721544672206 0.3773385096166127 0.7059220571661271 1.0 1.0 3 O75844 1 +Progressive inability to walk 0.3238242562363488 0.3752399237582032 0.7074820409397347 1.0 1.0 20 P00846,Q9H9S5 2 +Cerebral hypoplasia 0.3440977834991762 0.3746510423416404 0.7079200069961371 1.0 1.0 17 Q5MNZ6,Q86XL3 2 +Wide cranial sutures 0.3950008883210036 0.3730822771004928 0.7090872087943467 1.0 1.0 8 O75718,O75844,P98175 3 +Fetal distress 0.3328111554999579 0.3719425074623697 0.7099356555305909 1.0 1.0 28 Q9NPL8,Q9NVI7,P56556,P03886,O96000,O43676,Q86Y39 7 +Flared metaphysis 0.3938251128384414 0.3681441090586812 0.7127657825920626 1.0 1.0 8 Q96HY6 1 +Poor wound healing 0.4303843203117858 0.3676213973254981 0.713155557693649 1.0 1.0 5 O00170 1 +Hamartoma of the eye 0.3604068336512783 0.3670613431821601 0.7135732613639885 1.0 1.0 12 P49815,O60333,P31749 3 +Tetraparesis 0.337170526749965 0.3650694027698462 0.7150596000240204 1.0 1.0 36 P00846,Q7RTS9,Q9UBX3 3 +Complete duplication of phalanx of hand 0.4047407407407442 0.3648828249093037 0.7151988754562077 1.0 1.0 6 Q9ULC3,Q9Y2U8,Q9BXW9,P34897,P41227 5 +Ankyloblepharon 0.4047407407407438 0.3648828249093025 0.7151988754562086 1.0 1.0 6 P19447,O75569,O15111,P18074,P41227 5 +Elevated pulmonary artery pressure 0.3316598531537535 0.3636465401062708 0.7161219686957294 1.0 1.0 28 O75844,P00403,O96000,P03886 4 +Dystrophic fingernails 0.3925900404987538 0.3629766401393532 0.7166223344669898 1.0 1.0 8 P02545,P18074,O75844 3 +Finger agnosia 0.6543356022491911 0.3623355574538572 0.7171012898048177 1.0 1.0 2 P05067 1 +Mask like facies 0.3591991580107069 0.3608282804994231 0.7182278202472343 1.0 1.0 12 Q9H9S5 1 +Acne inversa 0.5248667850799451 0.3575648240875949 0.7206690064308485 1.0 1.0 3 Q9H488,Q9Y4L1 2 +Epidermal acanthosis 0.3561911545590129 0.3548480485365857 0.7227034301296855 1.0 1.0 13 Q06136,P31749 2 +Aplasia hypoplasia of the cerebral white matter 0.3836778136080888 0.354790382911042 0.7227466336318602 1.0 1.0 9 P03886 1 +Abnormally lax or hyperextensible skin 0.3366032360106749 0.3512029042906381 0.7254361314307645 1.0 1.0 43 Q9NWM8,Q9Y487,Q8NCH0,Q9UHX1 4 +Pseudoepiphyses of hand bones 0.4253585100205629 0.3502775041566352 0.726130446252945 1.0 1.0 5 P51812,O95202 2 +Pseudoepiphyses 0.4253585100205629 0.3502775041566352 0.726130446252945 1.0 1.0 5 P51812,O95202 2 +Abnormal electroretinogram 0.332943556682652 0.3496015429670441 0.72663775280403 1.0 1.0 32 P00846,Q96S66,O60220,Q15555,Q15067,Q8IY17 6 +Hypoplasia of the frontal lobes 0.366110280815676 0.3486729187926017 0.7273348775158122 1.0 1.0 11 Q86XL3 1 +Absent hand 0.520792847180227 0.3461283627344163 0.729246248936019 1.0 1.0 3 Q9Y297 1 +Restrictive behavior 0.3994994824893395 0.3451934069436668 0.729948974991903 1.0 1.0 6 Q01082 1 +Abnormality on pulmonary function testing 0.3222089868393537 0.345030241720931 0.7300716355542236 1.0 1.0 22 P35609,P49815,Q9H9S5,P31749 4 +Aplasia hypoplasia of the earlobes 0.3725306389612297 0.3392553415642451 0.7344173820205904 1.0 1.0 10 P21964,O00192,P98175,P10586 4 +Abnormal csf metabolite level 0.3288289976137639 0.3386599168092594 0.7348659398092208 1.0 1.0 56 Q8NI60,P00846,O43464,Q9Y3Z3,P00403,P56556,P03886,O95831,O96000,P13073,P42704,O43676,Q86Y39 13 +Abnormal cartilage morphology 0.3530784450536466 0.3384870549034665 0.7349961806928587 1.0 1.0 13 Q9UHX1 1 +Abnormality of visual evoked potentials 0.3198137793560869 0.3380401777185092 0.7353329106536266 1.0 1.0 21 O60220,Q15067,Q9GZY8,O60313,O43681 5 +Woolly hair 0.3968915850785676 0.3355293380158918 0.7372258175122706 1.0 1.0 6 Q96A33 1 +Typical absence seizure 0.346255839171789 0.3332774324430262 0.7389248728734339 1.0 1.0 15 Q01105,P61978 2 +Generalized hypopigmentation 0.3711397230175471 0.3329413337336883 0.7391785678351606 1.0 1.0 10 Q86YV9,Q6PGP7 2 +Adrenal hypoplasia 0.3851970488216173 0.3324816733452096 0.7395255759266652 1.0 1.0 8 O60826,O75844 2 +Minimal change glomerulonephritis 0.3417375630180281 0.3309206334025065 0.7407044360312436 1.0 1.0 16 Q8N1F7,Q14C86 2 +Focal impaired awareness seizure 0.320145593571563 0.3309187403484466 0.7407058659907939 1.0 1.0 22 O00429,P49815,Q01105 3 +Round face 0.3200865725308771 0.3305166809307416 0.7410095906067289 1.0 1.0 22 Q03164,Q32P28,O75718,P31749 4 +Abnormality of pelvic girdle bone morphology 0.3017786839644812 0.3302921204433365 0.7411792461582423 1.0 1.0 158 P55011,O95155,Q7RTS9,Q9Y5P6,Q9NVI7,Q96A33,Q03252,P50542,P42858,Q9UQE7,Q9H3S7,Q15125,P31749,Q96AY3,Q8TD16,Q14739,P00813,Q9UHX1,Q96PZ0,Q9Y487,P25054,P61978,P16435,Q8NCM8,O60826,Q8IWS0,O95831,Q96HY6,Q7Z4L5,Q8WVQ1,Q9UGU0,P06753,O75718,Q9H9S5,O75844,Q7LGA3,Q9BXW9,Q8N3R9 38 +Abnormal thyroid stimulating hormone level 0.6419058893163707 0.3298438625231089 0.7415179428464902 1.0 1.0 2 O14654 1 +Deviation of the hallux 0.3308857438727619 0.3296954576995242 0.7416300862528642 1.0 1.0 33 P55011,Q9UGU0,Q9H3S7,Q96PZ0,P31749,Q8N3R9,Q7LGA3,P42858,Q9Y4P3,Q15233,P21281 11 +Limitation of neck motion 0.4483608413355913 0.3283356984862386 0.7426578554119101 1.0 1.0 4 P02545 1 +Generalized muscle weakness 0.3316855833243319 0.3272151852534776 0.7435051363564953 1.0 1.0 35 Q92804,Q15165,P06753,Q68CQ7,P35637,Q9H9S5,P42858,O95831 8 +Short 1st metacarpal 0.3896722830722469 0.32717926334914 0.7435323040055819 1.0 1.0 7 Q8WVQ1 1 +Increased intramyocellular lipid droplets 0.389615689931032 0.3269614338257623 0.7436970547831634 1.0 1.0 7 Q8NI60 1 +Progressive 0.2719153941123496 0.3266752451348781 0.7439135254136757 1.0 1.0 107 Q99720,Q5MNZ6,O75298,Q13501,Q9H0B6,P31749,O00429,Q13126,Q9Y4W6,Q9GZY8,Q9NR28,O60313,Q96D71,Q8N1F7,P07942,O95470,O95831,Q8IY17 18 +Arteriovenous malformation 0.3892465118269298 0.3255415586090276 0.7447712347458961 1.0 1.0 7 Q92990,P31749 2 +Abnormality of salivation 0.3331434178452913 0.3241441533569904 0.74582890039262 1.0 1.0 44 P55011,Q13501,Q92804,Q15165,Q68CQ7,Q9NR77,Q05086,P35637,Q03252,Q14739,P55795,Q15233,Q01082 13 +Turricephaly 0.3502562949806286 0.3238003156045534 0.746089217240512 1.0 1.0 13 P07237,O00192,P21964,Q9ULC3,P16435,P50542 6 +Abnormality of the periorbital region 0.3020013956936691 0.3229999891198923 0.746695250303778 1.0 1.0 73 P40855,P50542,O00170,Q9Y4P3,Q15056,O75381,P28070,Q8NFH4,P51812,P38159,Q8N1F7,O43707,Q9Y5Y5,Q01082,P98175,Q08J23,P16435,P17980,Q6PGP7,Q8IWS0,Q14C86,Q7LGA3,Q9UPP1 23 +Synostosis involving bones of the hand 0.3513866245843859 0.3210876359963726 0.7481439796912754 1.0 1.0 12 P25054,P16435 2 +Parkinsonism 0.3273766269813477 0.3202861029758727 0.7487514569612213 1.0 1.0 30 O43464,Q06787,Q13501,Q99720,Q14203,Q9Y4W6,P35637,P07602,P61457,Q96QK1 10 +Adrenal hyperplasia 0.4451001829645612 0.3184742520881348 0.7501252225692909 1.0 1.0 4 P16435 1 +Aortic dissection 0.4158767772511764 0.3183998281153217 0.7501816686398002 1.0 1.0 5 P22413,O15460,P01889,Q02809 4 +Stage 5 chronic kidney disease 0.3286206434891953 0.3180935251822051 0.7504139949191135 1.0 1.0 32 Q7Z4L5,Q14C86,Q8N1F7,O95470,P49815 5 +Aplastic clavicle 0.4154304681106629 0.316927493055225 0.7512986201208132 1.0 1.0 5 O75419,Q9Y619 2 +Thoracic kyphoscoliosis 0.3911740759560284 0.3146627252848918 0.7530177484955216 1.0 1.0 6 Q9NSE4,P02545,O75844 3 +Hypopigmented macule 0.4145326907070131 0.3139736666774766 0.7535410391185628 1.0 1.0 5 P49815 1 +Increased serum lactate 0.272213228109355 0.3137175579982261 0.7537355641776813 1.0 1.0 109 P00846,Q8NI60,O43464,Q70HW3,P13073,Q9BWD1,O00429,P22695,Q9P0J1,P00403,P03886,Q86Y39,O14949,Q9UBX3,Q6P4A7,O95831 16 +Abnormal social behavior 0.294670380512381 0.3132582558905551 0.7540844621322729 1.0 1.0 76 O43464,Q15125,Q15067,Q9GZY8,P56556,P03886,Q9H0W8,Q15233,O96000,P49815,O43676,Q86Y39,Q01082,Q9UHX1 14 +Branchial anomaly 0.3802315901928554 0.3124389357166553 0.7547069638827559 1.0 1.0 8 Q9UHX1 1 +Abnormal size of the palpebral fissures 0.2620950286900325 0.3119423672288786 0.7550843234724853 1.0 1.0 93 P55011,Q03164,P42858,Q9H3S7,P38159,Q96DF8,P55795,Q01082,Q9UHX1,Q96PZ0,Q00577,P98175,Q13555,Q08J23,Q13868,P61978,Q8IWS0,Q9UGU0,Q15555,O75844,Q7LGA3,Q8N3R9 22 +Cutaneous finger syndactyly 0.442909593241043 0.3119212782973379 0.7551003509765042 1.0 1.0 4 O15111 1 +Vertebral compression fracture 0.3382896430501359 0.3112556083928357 0.7556063116067675 1.0 1.0 16 Q96AY3,P07237,Q32P28,O75718,O00170,Q96HY6 6 +Gastrointestinal hemorrhage 0.3307871876390179 0.3112304121127078 0.7556254647896785 1.0 1.0 38 P16930,Q9NZ08,P25054,Q14739,P49815,Q9UHX1 6 +Spinal rigidity 0.3488961569021827 0.3086413043773253 0.7575943974308434 1.0 1.0 12 Q8WXH0,P50402 2 +Platyspondyly 0.3278048498018426 0.3072457965171468 0.758656289582204 1.0 1.0 33 Q7RTS9,Q96AY3,O95831,P00813,Q96HY6 5 +Spondyloepiphyseal dysplasia 0.6327315773897656 0.3068953469075875 0.7589230309165351 1.0 1.0 2 Q9NSE4 1 +Gastroparesis 0.378739212678633 0.3064870181914836 0.7592338625602548 1.0 1.0 8 O43464 1 +Abnormality of endocrine pancreas physiology 0.4409410649211336 0.3060827880061826 0.7595416126022598 1.0 1.0 4 P16930 1 +Abnormal neuron morphology 0.3244517962740038 0.3057887982239926 0.7597654579276332 1.0 1.0 29 Q99720,Q92804,Q15165,Q68CQ7,P35637,Q8IY17 6 +Short columella 0.6321396862977265 0.30544574344238 0.7600266870360668 1.0 1.0 2 P49711 1 +Bowing of the legs 0.3221705660033869 0.3054197524935644 0.7600464797209778 1.0 1.0 59 Q7RTS9,Q8N0X7,Q8WVQ1,O75312,Q9NX62,Q9NR77,Q13126,Q32P28,O75718,Q7LGA3,P16435,Q8NCM8,Q01082,Q96HY6 14 +Molar tooth sign on mri 0.3885753111211296 0.3053282365031363 0.7601161724312133 1.0 1.0 6 Q10713,Q8WXW3 2 +Neuronal loss in central nervous system 0.3569454426690863 0.3050366924029421 0.7603382067052042 1.0 1.0 11 P42858,P35637 2 +Annular pancreas 0.3882060160084503 0.3040095475888408 0.7611206172914204 1.0 1.0 6 O95155 1 +Abnormal 5th finger morphology 0.2738168457159172 0.3021100861135211 0.7625681438764875 1.0 1.0 113 O95155,Q7RTS9,Q2M1P5,Q03164,Q03252,Q10713,Q9UQE7,Q9NZN8,Q5JRA6,Q8NFH4,Q15125,P31749,Q14739,Q15233,Q8IY17,Q9UHX1,O15294,O75845,O75419,Q05086,Q08J23,Q969G3,Q8NCM8,P13073,P21281,Q7Z4L5,Q8WVQ1,Q9UGU0,Q9BXW9 29 +Exaggerated cupid s bow 0.3829958760071392 0.3017985755607661 0.7628056168092352 1.0 1.0 7 P61978 1 +Sepsis 0.314250379236497 0.3006173396119411 0.7637063076423247 1.0 1.0 21 P00813 1 +Generalized myoclonic seizure 0.3298538478252166 0.3001891151972716 0.7640329072510115 1.0 1.0 40 P00846,Q08209,O00429,P03886,Q01105,Q9H3H1 6 +Abnormal ilium morphology 0.319316295793806 0.2969776767468322 0.7664835520812403 1.0 1.0 19 Q7RTS9 1 +Abnormality of small intestinal villus morphology 0.3763354079919929 0.2969719484510018 0.7664879254329746 1.0 1.0 8 Q6PGP7 1 +Corneal neovascularization 0.3815126503775692 0.2962488499725819 0.7670400453059887 1.0 1.0 7 O00192,P21964,Q92890 3 +Abnormality of extrapyramidal motor function 0.295156664030881 0.2939816240941388 0.7687719451027939 1.0 1.0 75 Q9H0B6,Q9Y4W6,Q9UBB4,O14949,P42858,P61457,Q9Y4P3,Q15056,Q9BPX6,P11802,Q06787,Q9H6K4,O43464,Q13501,Q9Y3Z3,Q14203,Q00577,P98175,Q99720,Q6DKK2,P06753,Q9BSH4,Q9NQX3,P35637,P07602,Q96QK1 26 +Aortic root aneurysm 0.3172836238671337 0.2938474448673941 0.7688744788708914 1.0 1.0 24 P55011,Q9UGU0,Q9H3S7,Q96PZ0,P06753,P02545,Q7LGA3,P42858,Q8N3R9 9 +Aplasia hypoplasia of the sternum 0.435935739706653 0.2914551561235133 0.7707032360126367 1.0 1.0 4 P98175 1 +Abnormal lung development 0.3272532762515839 0.2895721204468977 0.7721435982292206 1.0 1.0 50 Q7Z4L5,P31749,O75419,O75844,Q99567,P21964,Q96DF8,O96000,Q8NCM8,Q14739,Q9UHX1 11 +Lissencephaly 0.3224183752017511 0.2895334115511112 0.7721732155006102 1.0 1.0 57 Q86XL3,Q66GS9,Q9Y487,Q15392,Q9H9S5,P07942,Q96EK5,Q9BSJ2 8 +Left ventricular systolic dysfunction 0.3792891452265442 0.2879914821589465 0.7733532588393051 1.0 1.0 7 P02545,O75844 2 +Hemifacial spasm 0.4058289728954451 0.285893994501985 0.7749593135578969 1.0 1.0 5 Q10713,P31749 2 +Encephalocele 0.3374542812457434 0.2851837450378144 0.7755033730880436 1.0 1.0 15 Q8WXW3,Q10713,Q9H9S5,P07942 4 +Abnormal shape of the palpebral fissure 0.3603626691794304 0.2850782742283629 0.7755841743858671 1.0 1.0 10 P55795,Q9UHX1 2 +Concave nasal ridge 0.49762973987078 0.2845277306964227 0.7760059857842088 1.0 1.0 3 Q15125 1 +Motor neuron atrophy 0.3158332223706986 0.28408354935713 0.7763463535483253 1.0 1.0 24 Q99720,Q92804,Q15165,Q68CQ7,P35637 5 +Genu valgum 0.3270895128356938 0.2835222962926851 0.776776492579552 1.0 1.0 38 Q7LGA3,Q7RTS9,Q9NR77 3 +Abnormal circulating aspartate family amino acid concentration 0.3668090696304916 0.2832715954173768 0.7769686494797998 1.0 1.0 9 Q6PGP7,P16930 2 +Short foot 0.324169810336938 0.2810930876105472 0.7786390028092542 1.0 1.0 33 Q7Z4L5,O95155,Q9NX62,Q13555,Q96A33,Q08J23,Q10471,Q8NCM8,P42858,Q9UQE7,Q8N0X7 11 +Abnormal hair whorl 0.3153288633570485 0.2807022903385657 0.7789387519193862 1.0 1.0 24 P55011,Q9H3S7,Q96PZ0,Q7LGA3,P42858,Q8N3R9,O15294 7 +Abnormal circulating acetylcarnitine concentration 0.3815124052253151 0.2804517282816809 0.7791309551947427 1.0 1.0 6 O43772 1 +Broad clavicles 0.6203018644569454 0.2772597352391765 0.7815806746162972 1.0 1.0 2 A1X283 1 +Acantholysis 0.4026639582778302 0.2759404229463347 0.782593825730497 1.0 1.0 5 P16615 1 +Pes valgus 0.358074349297184 0.2751690580735368 0.7831863577570046 1.0 1.0 10 Q9UHX1 1 +Transposition of the great arteries 0.3753891686470619 0.2736922445112035 0.784321138257345 1.0 1.0 7 P02545,O75844,Q9ULC3 3 +Abnormal cortical bone morphology 0.3115904503591903 0.2736138767233788 0.7843813687424763 1.0 1.0 22 Q66GS9,Q86XL3,P31749 3 +Hip dysplasia 0.3227804969971825 0.2713632679636917 0.7861116503608139 1.0 1.0 54 P55011,O95155,Q9UGU0,Q9H3S7,Q96PZ0,Q15125,Q9NVI7,Q96A33,Q8TD16,P61978,Q7LGA3,P42858,Q8N3R9,Q9UQE7,Q9UHX1 15 +Paroxysmal ventricular tachycardia 0.4011050567667835 0.2710897328200706 0.7863220180386665 1.0 1.0 5 Q99996 1 +Retinal dysplasia 0.3567253764773007 0.2693711819502243 0.787644060290436 1.0 1.0 10 Q9H9S5 1 +Carcinoid tumor 0.3782430409413918 0.2691884124802529 0.7877846967800097 1.0 1.0 6 P25054 1 +Tics 0.3740605737480293 0.2688755235011665 0.7880254730042187 1.0 1.0 7 Q9UHX1 1 +Abnormal cardiomyocyte morphology 0.4913138478596667 0.268792903842925 0.7880890543661065 1.0 1.0 3 P35609 1 +Abnormal circulating arginine concentration 0.6164545723586916 0.2684351077969037 0.7883644186860124 1.0 1.0 2 Q9UJS0 1 +Coloboma 0.3221484428585137 0.2659538053633477 0.7902747860628607 1.0 1.0 54 Q9Y5P6,P31749,O60826,Q2M1P5,P78318,Q8WXW3,Q9H9S5,P61978,Q10713,Q96EK5,Q01082,Q8IY17,Q9UHX1 13 +Recurrent pneumonia 0.3141176989748824 0.2645202467268756 0.7913790656198088 1.0 1.0 19 P78318,P00813 2 +Limited wrist movement 0.3767931243732743 0.2642457521201226 0.7915905584445779 1.0 1.0 6 O75844 1 +Abnormality of cranial sutures 0.2598954373694366 0.2638990016155477 0.791857744979445 1.0 1.0 95 O95155,P40855,Q08209,Q9NX62,P21964,O75381,P31749,Q96AY3,Q32P28,Q00577,Q8NCH0,O75845,O75419,P98175,Q9Y487,P61978,P16435,O95831,O75718,O75844,Q9H0W8 21 +Widened subarachnoid space 0.3174074355325076 0.2637520011832723 0.7919710226681489 1.0 1.0 28 Q08209,P00403,P03886,Q01105,O95831 5 +Synostosis of joints 0.3237903626895228 0.2621363350824731 0.7932163346001033 1.0 1.0 37 Q8WVQ1,O95202,P25054,Q9H9S5,P16435,Q9Y4P3,Q15233,Q9UQE7,Q9UHX1 9 +Confetti like hypopigmented macules 0.4880662956433362 0.260887180851453 0.7941795108079688 1.0 1.0 3 P49815 1 +Tissue ischemia 0.3081914908642068 0.2608325255249836 0.7942216606691392 1.0 1.0 21 Q9NZ08 1 +Abnormality of the incisor 0.3204950728013428 0.2602444305643061 0.7946752339822996 1.0 1.0 32 P55011,Q9H3S7,Q96PZ0,Q00577,Q7LGA3,P42858,Q8N3R9,Q9BSJ2 8 +Apraxia 0.306791410119679 0.2599037518867372 0.7949380171185174 1.0 1.0 67 P55011,Q13501,Q6DKK2,O60220,Q9H3S7,Q96PZ0,Q00577,Q9Y4W6,O00429,Q05086,P35637,Q8WXW3,Q8N3R9,Q7LGA3,P42858,Q10713,Q15233,Q8N0X7 18 +Somatic mutation 0.3246028712547102 0.2598221205954452 0.7950009870248156 1.0 1.0 47 Q92804,P31749,O60333,P30154,P25054,Q01844,P16220,P00813 8 +Increased muscle glycogen content 0.4866785079928954 0.2575476003736068 0.796756074425014 1.0 1.0 3 O75648,Q9BUK6 2 +Abdominal pain 0.2644714764725543 0.2569319402397147 0.7972313132957893 1.0 1.0 86 Q70HW3,O60333,Q13423,Q9NZ08,P25054,Q14C86,P35637,Q01844,Q8N1F7,O43707,P49815,Q01082 12 +Iris coloboma 0.3230295308278086 0.2535621498310323 0.7998338411574972 1.0 1.0 38 P78318,Q8WXW3,Q9H9S5,Q10713,Q96EK5,Q01082,Q8IY17,Q9UHX1 8 +Abnormal circulating sex hormone concentration 0.3084074194722568 0.2528251752155399 0.8004033125559271 1.0 1.0 22 Q13423,P31749 2 +Anal fissure 0.609351879254223 0.2525849918781704 0.8005889287841175 1.0 1.0 2 P00533 1 +Retinal hamartoma 0.352612506458043 0.2518988609371936 0.8011192400455269 1.0 1.0 10 O60333,P31749 2 +Horizontal eyebrow 0.3588419129740631 0.2511073645558478 0.8017311022019005 1.0 1.0 9 O95155 1 +Abnormality of the calf 0.3042569350282908 0.2505773354361123 0.8021409064663998 1.0 1.0 68 Q7RTS9,Q8N0X7,Q8WVQ1,O75312,Q9NX62,Q9NR77,Q13126,Q32P28,O75718,Q7LGA3,P16435,Q8NCM8,O95831,Q01082,Q96HY6 15 +Pseudoepiphyses of the metacarpals 0.4202188803704275 0.2476381092249303 0.8044144220172393 1.0 1.0 4 O95202 1 +Thoracic aortic aneurysm 0.3212971348731778 0.2475922516350347 0.8044499064019006 1.0 1.0 36 P55011,O95155,Q9UGU0,Q9H3S7,Q96PZ0,P06753,P02545,O75844,Q8N3R9,Q7LGA3,P42858,Q9Y4P3,Q15056 13 +Impaired social interactions 0.3192098812096709 0.246952374990798 0.8049450819029316 1.0 1.0 55 O43464,Q15067,Q9GZY8,P56556,P03886,Q9H0W8,O96000,O43676,Q86Y39,Q01082,Q9UHX1 11 +Prominent supraorbital ridges 0.3441991533724804 0.2468210076790812 0.8050467516140913 1.0 1.0 11 Q8IWS0,P38159,Q9UPP1,P17980 4 +Abnormal conjunctiva morphology 0.3123427662500708 0.2445298163099689 0.8068205126452694 1.0 1.0 26 P28070,P31749,Q9NZ08,P06132,Q14739 5 +Soft tissue sarcoma 0.3213481761423218 0.2444187238433666 0.8069065419249313 1.0 1.0 37 P31749,Q13126,P25054,Q15392,P49815,Q01082 6 +Type ii diabetes mellitus 0.3220336466388286 0.2436452311663144 0.8075055942950666 1.0 1.0 39 Q9Y6M1,P31751,P03886,P43304,Q8IY17 5 +Abnormality of the parathyroid gland 0.3082712611149245 0.2428875114413677 0.8080925403537571 1.0 1.0 23 P00403,P03886,P21964,Q96DF8,P49815 5 +Anal stenosis 0.3915115543639411 0.2420132690107325 0.8087698816249911 1.0 1.0 5 O75419 1 +Mildly elevated creatine kinase 0.3107138783609681 0.2417677927518548 0.808960096312382 1.0 1.0 25 Q16836,Q13501,P06753,Q7Z406,P02545,P31483,Q9H9S5,P50570,Q9BPX6 9 +Intestinal polyp 0.3063607529104374 0.239621469202993 0.8106237195798842 1.0 1.0 22 P78549,P31749,P25054,P42892,Q15437 5 +Hypoplastic ischia 0.6031370227878128 0.2391921058546877 0.8109566236468742 1.0 1.0 2 Q14999 1 +Abnormal posterior segment imaging 0.4170244346333883 0.2391398639435669 0.8109971314056654 1.0 1.0 4 Q96S66 1 +Epileptic spasm 0.2996076489522932 0.2376435638177856 0.8121575592088912 1.0 1.0 70 P55011,P00846,Q13813,Q9H3S7,Q08209,Q00577,Q9GZY8,Q9UBX3,P03886,P15311,Q01105,P13073,P49815,Q71SY5,Q01082 15 +Abnormal clavicle morphology 0.3112426892872985 0.2372597162619479 0.8124553116732021 1.0 1.0 26 Q7Z4L5,Q96AY3,O75419,Q2M1P5,O75844,Q8NCM8,Q14739 7 +High forehead 0.260950308304091 0.235356438979899 0.813932093142228 1.0 1.0 100 P55011,P40855,Q08209,Q9NX62,Q9NVI7,Q03164,P50542,P42858,Q9Y4P3,O75381,Q9H3S7,O95202,Q14739,Q9Y5Y5,Q01082,Q96PZ0,Q00577,Q2TAA5,Q13555,P25054,Q13868,P21281,Q71SY5,Q9UGU0,P78318,Q7LGA3,Q10471,Q8N3R9 28 +Increased csf lactate 0.3204669831249757 0.2339742383957259 0.81500497839446 1.0 1.0 50 Q8NI60,P00846,O43464,P00403,O95831,P03886,O96000,P13073,P42704,O43676,Q86Y39 11 +Sagittal craniosynostosis 0.3641660888431836 0.2339094668142252 0.8150552636147173 1.0 1.0 7 O75419,P21281,P61978 3 +Abnormality of the upper respiratory tract 0.2619391518089954 0.2318655877053392 0.8166424132238572 1.0 1.0 102 Q7RTS9,P28070,Q92804,Q15165,Q03518,Q13501,Q68CQ7,Q86YV9,P25054,Q13277,P35637,P16435,Q14739,P00813,Q01082,Q96HY6,Q9UHX1 17 +Nyctalopia 0.3144601347745558 0.2304518511959115 0.8177406737603699 1.0 1.0 30 O75381,P40855,Q96S66,Q9Y287,O75312,Q15555,Q6P4Q7,P50542,Q10713,P38435 10 +Lymphoproliferative disorder 0.3868433756651199 0.2283610339161394 0.8193655795676387 1.0 1.0 5 P33991 1 +Postural instability 0.3015132665650151 0.2279901861316912 0.8196538699606872 1.0 1.0 20 O43464,Q9NR77 2 +Radioulnar synostosis 0.3043993950093812 0.2270922493719968 0.8203520107280933 1.0 1.0 22 Q8WVQ1,O95202,P25054,P16435,Q9Y4P3,Q9UQE7 6 +Skin erosion 0.3576781596926332 0.2263329451307077 0.8209424766159206 1.0 1.0 8 O75844,P98194,P06132 3 +Central diabetes insipidus 0.5969221663214028 0.2262491719080509 0.8210076283059105 1.0 1.0 2 O76024 1 +Pseudoarthrosis 0.4723171603714636 0.2243803732503991 0.8224613412450053 1.0 1.0 3 O75844 1 +Abnormality of the peritoneum 0.3023321962046813 0.2234098282961972 0.8232165557520577 1.0 1.0 21 Q14C86,Q01844,Q8N1F7 3 +Nonprogressive cerebellar ataxia 0.4712847838958054 0.2220955255235028 0.8242395209998921 1.0 1.0 3 Q4G0N4,Q69YN2 2 +Biparietal narrowing 0.3385345579609519 0.221965054000163 0.8243410876173565 1.0 1.0 11 Q10713,O75845,Q8WXW3 3 +Vocal cord paresis 0.4709597832690547 0.2213790343882681 0.8247973155982036 1.0 1.0 3 Q8TB36 1 +Arrhinencephaly 0.3303560394149366 0.2197670954908612 0.8260525471316897 1.0 1.0 12 Q9Y3Z3,O00192,Q2M1P5,P21964,P21281 5 +Cutaneous syndactyly 0.3287564378923107 0.2170531349966476 0.8281669361084607 1.0 1.0 13 Q9Y619,P98175,Q2M1P5,O15111,P21281 5 +Joint dislocation 0.2588385664881356 0.2151487700237445 0.8296513311323295 1.0 1.0 99 Q15125,P31749,Q8NCH0,Q9NX62,Q9Y487,P25054,Q96A33,Q8TD16,Q9H9S5,O75844,Q9UHX1 11 +Medial flaring of the eyebrow 0.4665482534043808 0.2117865661237809 0.8322735494789362 1.0 1.0 3 Q9NQ48,Q9BW83 2 +Abnormal size of the clitoris 0.2987333401066665 0.2106752191919886 0.8331407128259687 1.0 1.0 20 O75381,P40855,O75419,P50542,P16435 5 +Broad long bones 0.3175600075391441 0.2087186458716692 0.8346678834076278 1.0 1.0 40 P55011,Q9H3S7,Q96PZ0,Q08J23,Q13868,Q7LGA3,P42858,Q8N3R9,Q71SY5,Q9UHX1 10 +Exercise intolerance 0.3144958660284708 0.2084271022088858 0.8348954964724613 1.0 1.0 34 Q8NI60,Q9H2D1,Q9Y2R0,P06753,P00403,P03886,Q53H12,Q8NFF5 8 +Hyporeflexia 0.2723355978523999 0.2081988173515181 0.8350737319750752 1.0 1.0 122 Q9H0B6,Q08209,P03886,O43681,Q10713,P00846,O60333,Q9NR77,Q8TD16,O14979,Q8IY17,Q13501,O95831,Q71SY5,Q99720,P07196,P06753,Q7Z406,Q15067,P35637,Q9H9S5,Q96BR5 22 +Solitary median maxillary central incisor 0.4045010364228464 0.2072121726563928 0.8358441612136047 1.0 1.0 4 Q14683,Q8N3U4,A5YKK6 3 +Anencephaly 0.3147661295770717 0.205293236374866 0.8373430281154308 1.0 1.0 17 Q9Y3Z3,Q92890,O00192,Q2M1P5,P21964,Q53EZ4,P21281 7 +Microdontia 0.3105654357223651 0.2043790856911125 0.8380572724487316 1.0 1.0 30 P21281,P07237,Q9Y487,Q15555,Q96A33,Q7LGA3,Q9Y4P3,Q15056,Q9UQE7 9 +Microtia third degree 0.4629829201078638 0.2042163721583579 0.8381844178155073 1.0 1.0 3 O75419 1 +Narrow palpebral fissure 0.3040650539222526 0.2039552737168113 0.8383884505899473 1.0 1.0 19 Q03164,Q96DF8 2 +Cerebral visual impairment 0.2994962291467433 0.2035604337979663 0.8386970149436843 1.0 1.0 68 P55011,O60220,Q08209,Q01433,Q9UID3,Q8NB90,P00403,Q96A33,P03886,Q96N66,P15311,Q01105,Q08J23,P35606,Q96CU9,Q71SY5,Q9BSJ2 17 +Absence of subcutaneous fat 0.3575376772854433 0.2018282325705808 0.8400510093139162 1.0 1.0 6 P02545,P18074,O75844 3 +Abnormal sternal ossification 0.4019033617021407 0.2008729734410747 0.8407979010340665 1.0 1.0 4 O95202 1 +Hypokinesia 0.3235730242756878 0.2005569239955462 0.8410450432817911 1.0 1.0 14 Q99567,O95831,P06753,P42858 4 +Abnormal paranasal sinus morphology 0.3000010948495234 0.1994550711700781 0.8419067852007234 1.0 1.0 22 P28070 1 +Hypoplastic nipples 0.3258502522787866 0.1992723452213371 0.8420497106534146 1.0 1.0 12 Q96A33 1 +Abnormal dentin morphology 0.4012383385699729 0.199266029943816 0.8420546504603275 1.0 1.0 4 Q96AY3 1 +Impacted tooth 0.4006129031265307 0.1977606968242088 0.8432322981842231 1.0 1.0 4 O75844 1 +Joint hypermobility 0.2606532482520058 0.1977101627976195 0.8432718379107116 1.0 1.0 104 P55011,Q03164,P21964,Q03252,P42858,Q9H3S7,Q01105,Q9NWM8,Q8N0X7,Q9UHX1,Q96PZ0,O75419,Q9Y487,Q05086,Q08J23,Q8IWS0,Q8WVQ1,Q7LGA3,Q8N3R9 19 +Nephritis 0.3023852816102204 0.1965961803914802 0.8441435598865952 1.0 1.0 24 Q12769,Q8NFH4,Q14C86,Q96AX1,P35579,Q03252,Q8N1F7,O43707 8 +Large face 0.2937340357946683 0.1957300607712821 0.8448214543797028 1.0 1.0 71 P55011,Q9NVI7,P21964,O00170,Q10713,P42858,Q9H3S7,P31749,O95721,Q8WXW3,Q15233,Q96PZ0,Q00577,P25054,P61978,Q08J23,Q9UGU0,P06753,Q7LGA3,Q8N3R9,Q9UPP1 21 +Autoamputation of digits 0.4576672587329943 0.1932350370239612 0.8467749002264673 1.0 1.0 3 P48643,Q9H4A3 2 +Acral ulceration 0.4576672587329943 0.1932350370239612 0.8467749002264673 1.0 1.0 3 P48643,Q9H4A3 2 +Abnormality of taste sensation 0.4576672587329821 0.1932350370239359 0.846774900226487 1.0 1.0 3 O95163,Q9H4A3 2 +3 methylglutaconic aciduria 0.3236078557142197 0.1929966366812112 0.846961602112932 1.0 1.0 13 O43464,Q53H12,Q9H6K4 3 +Abnormal anatomic location of the heart 0.3316742488842514 0.1927689768350172 0.8471399006587477 1.0 1.0 11 Q10713,Q8WXW3,O75844 3 +Aplasia hypoplasia of the 5th finger 0.3121690687685884 0.1913596750101842 0.8482438108952923 1.0 1.0 17 Q969G3,P13073,Q9UQE7,Q9NZN8,Q9UHX1 5 +Viral encephalitis 0.5785735424681919 0.1907017505375356 0.848759267131941 1.0 1.0 2 Q9Y4L1 1 +Mandibular aplasia 0.3533639459700385 0.1891298535456792 0.8499910439656517 1.0 1.0 6 O15111,O75419,Q9Y619 3 +Hyperglycemia 0.371903153929518 0.1869598864408529 0.8516920843078744 1.0 1.0 5 P42704,O75844 2 +Abnormality of the plantar skin of foot 0.3152430596554728 0.1861529808791357 0.8523247952100697 1.0 1.0 46 P35609,P31749,Q9Y487,O95721,Q06136,P16615,P61978,P09493,Q15437 9 +Neurofibromas 0.3490112107668107 0.183642618832332 0.8542938266757205 1.0 1.0 7 Q01082,P31749 2 +Dyskinesia 0.2972975605452036 0.182178079061143 0.8554429754900343 1.0 1.0 68 P55011,P00846,O43464,Q08209,Q9UBB4,Q00577,Q9UBB6,P03886,Q96N66,P43246,P15311,Q01105,Q08J23,Q9UBX3,P42704,Q96QK1,Q71SY5,Q9BPX6 18 +Macule 0.2885414184531509 0.1796707654316194 0.8574110457192714 1.0 1.0 73 P55011,O95155,Q9UGU0,Q9H3S7,Q96PZ0,P31749,O60333,P25054,Q6PGP7,Q06136,P16615,O75844,Q8N3R9,Q7LGA3,P42858,P49815,Q15437,Q15233 18 +Mottled pigmentation 0.392134661056045 0.1779293278272288 0.8587784780610221 1.0 1.0 4 O75844 1 +Tachycardia 0.3062530233019137 0.1761188235884672 0.8602005929823422 1.0 1.0 30 Q9BTV4,O43772,P35609,O60333,P0DP25,P02545,P42892,P46976,Q99996,Q14BN4,P09493,Q8NFF5 12 +Limb ataxia 0.2990359602261327 0.1757388838216222 0.8604990858064183 1.0 1.0 24 O75298,Q13501,P07196,Q9Y4W6,Q9NR77,O15020 6 +Obstructive sleep apnea 0.3202464571054544 0.1744450708058741 0.8615156959095664 1.0 1.0 12 P42704,Q96A33 2 +Abnormal form of the vertebral bodies 0.2523893447179421 0.173953729828391 0.8619018259727635 1.0 1.0 88 Q5JRA6,Q7RTS9,Q8WVQ1,Q15125,P31749,Q96AY3,O75845,Q14739,P25054,Q32P28,Q8WXW3,P16435,O00170,Q10713,O95831,P00813,Q96HY6,Q9UHX1 18 +Bradycardia 0.3179390522046638 0.1738656268838475 0.8619710669133085 1.0 1.0 14 O43464,O43772,P0DP25,O75208,Q99996 5 +Hypoventilation 0.3156275667238531 0.1735535848517425 0.8622163122360458 1.0 1.0 15 Q9H9S5,P61978,P06753,Q00577 4 +Easy fatigability 0.2970999729321408 0.1725647112834544 0.8629935920131016 1.0 1.0 23 P06753,Q9Y5P6,Q53H12,P61978,O00170,Q9NWM8 6 +Oligodactyly 0.326505698789629 0.1714634248184782 0.8638593872794025 1.0 1.0 11 Q9Y297,P25054 2 +Ventricular fibrillation 0.3448421539283518 0.1705554944394678 0.8645732953468219 1.0 1.0 7 Q99996,Q14BN4 2 +Abnormality of the foot musculature 0.4458445302251404 0.1701360495903869 0.8649031433158063 1.0 1.0 3 O14979 1 +Pulmonary hypoplasia 0.2991358153819169 0.1679780459965212 0.8666005504106233 1.0 1.0 25 O75419,O75844,Q99567,O96000,Q8NCM8,Q14739 6 +Slender build 0.3253443943933175 0.1667610266753566 0.8675580854120912 1.0 1.0 11 P06753 1 +Abnormal tricuspid valve morphology 0.3177241935916436 0.1663005756673193 0.8679204130379414 1.0 1.0 13 P51812,Q92890,O00192,P21964,O60826,Q15233 6 +Generalized limb muscle atrophy 0.3360995629677937 0.1658226967390853 0.868296483985832 1.0 1.0 9 P06753,Q8IY17 2 +Slowly progressive 0.3087187531337971 0.1646406690250669 0.8692268187479291 1.0 1.0 56 O14979,Q99720,P07196,Q14203,P05023,Q9Y4W6,O00429,O60333,Q9NR77,P02545,P31483,Q96BR5,P50402,P46976,O43707,P50570,O15020,O95831 18 +Multiple suture craniosynostosis 0.3446516871701622 0.1636330812345058 0.8700200006470873 1.0 1.0 6 O00192,P21964 2 +Tricuspid atresia 0.3446516871701622 0.1636330812345058 0.8700200006470873 1.0 1.0 6 O00192,P21964 2 +Generalized lipodystrophy 0.3855967672621646 0.1633773053859873 0.8702213704714712 1.0 1.0 4 O75844 1 +Weakness of long finger extensor muscles 0.4410316697305324 0.1612609105975966 0.8718879090847633 1.0 1.0 3 Q13501 1 +Abnormality of t cell physiology 0.306381577776708 0.1610287159829195 0.872070783689167 1.0 1.0 17 P21964,Q96DF8,P00813 3 +Abnormality of the peripheral nervous system 0.2621547006077303 0.1604983374623243 0.8724885311635149 1.0 1.0 111 O60220,Q9UBB4,O60313,O43681,P21964,P42892,P50570,Q10713,Q96EK5,Q9NSV4,Q15125,O60333,Q9NR77,O95721,Q8WXW3,O43464,Q99996,O95831,Q71SY5,Q99720,P07196,Q7Z406,Q15067,Q9GZY8,P0DP25,P07602,Q9BXW9,Q96QK1 28 +Mutism 0.3092706366253576 0.1569785325429147 0.8752617668774181 1.0 1.0 16 P42858,P56556,P35637 3 +Glomerulonephritis 0.2914517283626755 0.1569676557429355 0.8752703390434782 1.0 1.0 21 Q14C86,O43707,Q03252,Q8N1F7 4 +Preaxial foot polydactyly 0.3421944520134991 0.1566946487912944 0.8754855046292136 1.0 1.0 6 Q2M1P5,O95202 2 +Abnormality of the thymus 0.2950210205480591 0.1522202870437037 0.8790131936693657 1.0 1.0 19 Q6PGP7,P21964,P00813,P31749 4 +Hamartoma of tongue 0.3794405588850638 0.1502735405376864 0.8805488075130836 1.0 1.0 4 Q8NCM8 1 +Abnormal blistering of the skin 0.2961960146026744 0.1499992854370206 0.8807651790201971 1.0 1.0 25 O95155,Q9NZ08,Q06136 3 +Aortic regurgitation 0.2946061441954405 0.1487799134186116 0.8817273009865416 1.0 1.0 24 O75844,Q6PGP7,Q9NZ08,Q9UHX1 4 +Facial edema 0.3029730589243407 0.1487145077826165 0.8817789129870219 1.0 1.0 31 P28070,Q8NFH4,Q14C86,P50542,O00170,Q8N1F7,O43707,Q9Y4P3,Q01082 9 +Hyperconvex fingernails 0.3391439735679458 0.1482389234887431 0.8821542146401886 1.0 1.0 6 O95202 1 +Decreased ldl cholesterol concentration 0.3773238035308238 0.145903240146292 0.8839977736977258 1.0 1.0 4 Q15800 1 +Distal sensory impairment of all modalities 0.3772579212318503 0.1457683335805893 0.8841042749816992 1.0 1.0 4 O15270,P48643,O15269 3 +Distal sensory loss of all modalities 0.3772579212318503 0.1457683335805893 0.8841042749816992 1.0 1.0 4 O15270,P48643,O15269 3 +Pigmentary retinopathy 0.3096622886396461 0.1449288250741933 0.8847670675832096 1.0 1.0 47 P00846,Q16836,Q96S66,Q15555,Q15067,P00403,P03886,Q9H9S5,Q8IY17 9 +Plagiocephaly 0.3057593635535058 0.1448674314320235 0.8848155410802343 1.0 1.0 35 P21281,Q9UGU0,Q9Y3Z3,Q08209,Q96A33,Q969X5,Q01105,Q14696,Q10713,Q15233,Q9UQE7,Q01082 12 +Abnormality of the bladder 0.2668874128361745 0.1436595334514035 0.8857693272765401 1.0 1.0 121 Q08209,Q9UBB4,P22626,O43681,P21964,P50570,O00170,Q9Y4P3,Q15056,Q9UQE7,Q06787,P31749,P51812,Q9NR77,Q9NWM8,Q8N0X7,Q9UHX1,Q13501,Q86XL3,Q8NCH0,Q66GS9,O75419,P61978,Q969G3,P16435,P35606,Q99720,O75298,P07196,P35637,P07602,Q10471,Q15058,Q96QK1 34 +Phthisis bulbi 0.3358032009484314 0.1433362714256314 0.886024611120263 1.0 1.0 7 Q14683,Q6KC79,P27448,Q9UQE7,O60885,Q6W2J9 6 +Pathologic fracture 0.3089039150023877 0.1416832274200928 0.8873302238582133 1.0 1.0 15 O75845,Q13126,O15269 3 +Unconjugated hyperbilirubinemia 0.4292944494477164 0.1409058532412898 0.887944318067788 1.0 1.0 3 O14936 1 +Gowers sign 0.3106759350461305 0.1406996644987627 0.8881072101505074 1.0 1.0 14 Q8TD16,P07196 2 +Abnormal peripheral nervous system morphology 0.2903547409147562 0.1398431667236978 0.8887839062657115 1.0 1.0 163 P40855,Q9H0B6,Q9Y4W6,P03886,O60313,P42704,Q9BPX6,P00846,O75381,P31749,O60333,Q9NR77,O95721,Q01082,Q8IY17,Q9UHX1,P25054,P00403,P49815,O95831,Q71SY5,Q99720,Q6DKK2,P07196,P06753,Q15067,Q9GZY8,P35637,Q9H9S5 29 +Secundum atrial septal defect 0.4283599763173485 0.139363885614016 0.8891626089256666 1.0 1.0 3 P34897,A1X283 2 +Curly eyelashes 0.3357037037037058 0.1389148824761323 0.8895174104800165 1.0 1.0 6 Q8N3U4,Q14683,Q6KC79,Q9UQE7,O60885 5 +Edema of the dorsum of hands 0.5469073690441026 0.1388235575712724 0.8895895779830283 1.0 1.0 2 Q9Y263 1 +Edema of the dorsum of feet 0.5469073690441026 0.1388235575712724 0.8895895779830283 1.0 1.0 2 Q9Y263 1 +Abnormality of peripheral nerves 0.3083414408994248 0.1370503591613249 0.8909909897643913 1.0 1.0 49 Q99720,P07196,Q7Z406,Q9UBB4,O60333,Q9NR77,O95721,Q9GZY8,Q8TB36,O43681,P02545,P07602,P50570,O95831,Q71SY5 15 +Hypoplasia of the pons 0.2894410573241054 0.1358945828669085 0.8919046179948147 1.0 1.0 22 Q9UID3 1 +Female hypogonadism 0.3344177737840294 0.1354879509035811 0.892226090201151 1.0 1.0 6 O75844,O00170 2 +Hip dislocation 0.2938332895936152 0.1353671691558337 0.8923215803906097 1.0 1.0 67 P31749,Q9Y487,P25054,Q96A33,Q8TD16,Q9H9S5,O75844,Q9UHX1 8 +Synostosis of carpals tarsals 0.3268555419281608 0.1342016805963156 0.8932430970114542 1.0 1.0 9 P25054 1 +Carpal synostosis 0.3268555419281608 0.1342016805963156 0.8932430970114542 1.0 1.0 9 P25054 1 +Abnormality of the nasal bone 0.3713355048859837 0.1339170296542461 0.8934681838672904 1.0 1.0 4 P35222,O14974,P10644 3 +Lower limb muscle weakness 0.3078093525825512 0.1335495249339939 0.8937587997806213 1.0 1.0 43 P00846,O75298,P07196,P06753,P31749,Q9NR77,Q8IY17 7 +Broad neck 0.3099345559644687 0.1307954771123082 0.8959371010012549 1.0 1.0 12 P78318,Q15555,Q99567 3 +Lower limb hyperreflexia 0.2959648424042457 0.1297973421052316 0.8967267658190563 1.0 1.0 18 P13073,Q05086,Q9Y4W6,Q14739 4 +Abnormal growth hormone level 0.2964061635625926 0.1280723340082059 0.8980917299813997 1.0 1.0 28 Q4J6C6,Q03164,P31749 3 +Alkalosis 0.3679929884854157 0.1274700068669696 0.8985684105591141 1.0 1.0 4 O00170 1 +Renal tubular dysfunction 0.3054583634938898 0.1268966427269213 0.8990222038768758 1.0 1.0 39 P40855,P16930,P00403,P03886,O96000,O43676,Q86Y39 7 +Abnormal subarachnoid space morphology 0.3003706635462576 0.1261936732604325 0.8995786193373587 1.0 1.0 32 Q08209,P00403,P03886,Q01105,O95831 5 +Global brain atrophy 0.2903244714059525 0.1234353124218636 0.9017623956041534 1.0 1.0 24 Q9H0W8,P35637,O60220,Q9UHX1 4 +Tongue nodules 0.4180118998204819 0.1230615467861923 0.9020583609913456 1.0 1.0 3 P98175 1 +Kinetic tremor 0.3015166986276118 0.122336899839268 0.902632209616669 1.0 1.0 34 Q9Y287,P31749,Q9Y4W6,P07602,O43681,O15020,Q15233,Q01082,Q8IY17 9 +Generalized onset motor seizure 0.3055073489745573 0.1219534289126962 0.9029359012212556 1.0 1.0 52 P00846,Q08209,O00429,Q05086,P03886,Q01105,Q9H3H1 7 +Abnormality of the metopic suture 0.3044377817955042 0.1212421449433945 0.9034992434782808 1.0 1.0 15 Q9H0W8,P61978,Q00577 3 +Alopecia of scalp 0.3257893316900054 0.1206101521333419 0.9039998273105844 1.0 1.0 8 Q15125 1 +Retrognathia 0.2460690420244611 0.1204920127211444 0.9040934064745444 1.0 1.0 90 Q15125,Q8NCH0,Q66GS9,Q4J6C6,P78318,Q15392,O75844,Q7LGA3,Q96DF8,Q99567,Q9UHX1 11 +Tibial torsion 0.4162226169330942 0.1203859646789892 0.904177409103144 1.0 1.0 3 Q8TAB3,Q9Y5S9 2 +Panhypopituitarism 0.5327019828351653 0.1194099628684481 0.9049505685433084 1.0 1.0 2 Q8N3U4 1 +Cyclopia 0.5327019828351653 0.1194099628684481 0.9049505685433084 1.0 1.0 2 Q8N3U4 1 +Abnormal dura mater morphology 0.5327019828351653 0.1194099628684481 0.9049505685433084 1.0 1.0 2 Q8N3U4 1 +Median cleft lip 0.5327019828351653 0.1194099628684481 0.9049505685433084 1.0 1.0 2 Q8N3U4 1 +Syncope 0.3058013238188949 0.1192682270851006 0.9050628549017896 1.0 1.0 14 P31749,P0DP25,Q99996,Q969G3,Q14BN4 5 +Pseudohypoaldosteronism 0.5321100917431263 0.1186517611379913 0.9055512555047956 1.0 1.0 2 Q9H4A3 1 +Abnormal hand bone ossification 0.3267204602227086 0.1176316035507275 0.906359562772226 1.0 1.0 7 Q15125 1 +Mucosal telangiectasiae 0.317535264505467 0.11696154594393 0.906890526162856 1.0 1.0 10 Q14739,P31749 2 +Generalized clonic seizure 0.3258921184658691 0.115371523637685 0.9081506490639436 1.0 1.0 7 P07602,Q8TAB3,O14936 3 +Gastrointestinal obstruction 0.304845306265943 0.1151458846281493 0.9083294910721028 1.0 1.0 14 P25054,Q01844 2 +Broad hallux phalanx 0.3606751554634209 0.1139660742792186 0.9092646869825232 1.0 1.0 4 Q9UPW6,Q6DKJ4,P49711 3 +Delayed ability to walk 0.2900367643782584 0.113221237535239 0.9098551588094584 1.0 1.0 68 P55011,P48449,Q99720,P35609,Q9UGU0,Q96PZ0,Q01433,Q05086,Q96N66,P35637,Q01105,Q96D71,Q03252,P61978,Q10471,Q10713,Q15233,Q9UBB6 18 +Abnormality of the fetal cardiovascular system 0.3249614076666355 0.1128491302902631 0.910150166749369 1.0 1.0 7 O60826,P47985,P16435 3 +Perisylvian polymicrogyria 0.3406398104265284 0.1123825397292385 0.9105200988974916 1.0 1.0 5 Q15042,P42345,P34897,P42356 4 +Abnormality of the pulmonary vasculature 0.3050604265366514 0.1119315208755351 0.910877703595962 1.0 1.0 45 P55011,Q9H3S7,Q96PZ0,O75718,Q15392,Q96DF8,Q7LGA3,P42858,Q6PGP7,Q8N3R9 10 +Ventricular hypertrophy 0.3043931694911388 0.1116412206784293 0.9111078869303746 1.0 1.0 42 P35609,O43772,O75880,P00403,P03886,O75208,Q9H9S5,O75844,O00170,Q15233 10 +Finger syndactyly 0.3048358351915339 0.1113564099629614 0.9113337248234168 1.0 1.0 44 P31749,P98175,P25054,Q05086,Q9BXW9,O60826,Q96EK5,Q9Y297,Q71SY5,Q8IY17 10 +Elevated serum acid phosphatase 0.3591945513769505 0.1113358935147667 0.9113499934187052 1.0 1.0 4 P07602,Q01968,Q9NZJ7 3 +Gastrostomy tube feeding in infancy 0.2997781444645672 0.1113055908661509 0.9113740220866512 1.0 1.0 34 Q99720,Q08209,O00429,P35637,Q01105,P42704 6 +Abnormal activity of mitochondrial respiratory chain 0.300720016456132 0.1108389572662533 0.91174405223355 1.0 1.0 58 Q70HW3,Q9Y2R0,P03886,O96000,P13073,P42704,O43676,Q86Y39,Q9UBX3 9 +Abnormality of complement system 0.3572073603405426 0.1078597552628443 0.9141069414668872 1.0 1.0 4 Q03252 1 +Broad nasal tip 0.301006355707597 0.1073170641641767 0.9145374474755904 1.0 1.0 57 P10586,Q9Y487,P25054,Q7LGA3,Q13868,O95831,Q9UPP1,Q9UHX1 8 +Abnormal brain positron emission tomography 0.3228305616239775 0.1071421448051534 0.9146762128584858 1.0 1.0 7 Q13501,P31749 2 +Abnormal endocardium morphology 0.2954417996205075 0.1065966357084477 0.9151089876941984 1.0 1.0 17 Q9NZ08 1 +Resting tremor 0.2914084675949256 0.1065897191101042 0.9151144750783922 1.0 1.0 18 Q06787,P07602,Q96QK1,Q9H6K4,Q9BPX6 5 +Anteverted ears 0.4043812907045607 0.1037326950429547 0.917381479718681 1.0 1.0 3 P27635,O15347 2 +Central nervous system cyst 0.2989023650425902 0.1023701024598552 0.9184629137547712 1.0 1.0 59 P00846,O95202,Q9Y5P6,Q15125,Q9UID3,Q9Y487,Q2M1P5,Q9H9S5,Q99567,Q969G3,Q8NCM8,O60826,Q9H0W8,Q9BSJ2,Q9UHX1 15 +Falls 0.3195000665448612 0.1022584171191945 0.9185515605607176 1.0 1.0 8 Q8WVX9,Q5T8D3,Q01082,Q9BQT8 4 +Abnormality of the nasal septum 0.3356437625405726 0.1020461803158463 0.9187200197882904 1.0 1.0 5 Q15233,P21281 2 +Anotia 0.3339521787353312 0.0986470694294222 0.921418496253644 1.0 1.0 5 O15111,O75419 2 +Leukoencephalopathy 0.2487542264409947 0.0980350897073581 0.9219044300028088 1.0 1.0 97 Q9Y5P6,Q08209,P03886,O60313,O43681,P07942,Q86Y39,O95202,O00429,P56556,Q01105,O43676,Q9UHX1,Q9NPL8,Q9Y3Z3,O96000,O95831,P49770,P07602,Q9H9S5,Q96BR5,Q01433 22 +Long eyelashes 0.3015173263680878 0.0974837660413331 0.9223422256463696 1.0 1.0 40 Q4J6C6,Q03164,Q9UID3,Q9UHX1 4 +Neoplasm of the eye 0.2934414153611729 0.0970787254305765 0.922663875697156 1.0 1.0 17 P49815,O60333,P31749 3 +Metamorphopsia 0.5119857946137983 0.0952148793276615 0.9241441516872496 1.0 1.0 2 P22413 1 +Vitreous hemorrhage 0.5119857946137967 0.0952148793276598 0.9241441516872512 1.0 1.0 2 P35222 1 +Areflexia 0.2465287061117246 0.0935873501670447 0.9254369586119218 1.0 1.0 94 Q9Y5P6,Q9BT22,O60313,P50542,P50570,P05023,O00429,O60333,Q9NR77,O95721,Q9BQT8,Q8TD16,Q9H6K4,Q8IY17,Q13501,P61978,O95831,Q71SY5,P07196,P06753,Q7Z406,Q15067,Q9H9S5 23 +Acute coronary syndrome 0.2785300936574348 0.0932487427664643 0.9257059519201418 1.0 1.0 20 O75844,Q9NZ08 2 +Status epilepticus 0.3012911836381885 0.092689116916996 0.9261505432311488 1.0 1.0 53 P05023,Q08209,Q9UBB4,O00429,Q9Y487,Q9UID3,P07602,Q15392,P42892,Q01105,Q03252,P49815 12 +Abnormal shoulder physiology 0.3478874678924897 0.0923797853901197 0.9263962996640616 1.0 1.0 4 O75844 1 +Polysplenia 0.3952042628774443 0.0920667236654658 0.9266450267993644 1.0 1.0 3 P54577,Q9ULC3 2 +Abnormal mitochondrial shape 0.3305754392990026 0.0920142480850513 0.9266867192823388 1.0 1.0 5 Q9GZY8 1 +Patchy alopecia 0.3945800405119895 0.0913118553008973 0.9272447981758384 1.0 1.0 3 O75844 1 +Spastic paraparesis 0.2779301771815317 0.0900091917793129 0.9282799104964246 1.0 1.0 20 Q6DKK2,Q9Y3Z3,Q9Y619,Q9Y5Y5,Q9Y4W6,Q9H6K4,Q8N0X7 7 +Abnormality of the brainstem white matter 0.3933192760541661 0.0898020731972786 0.928444500675904 1.0 1.0 3 Q10713 1 +Hypoplastic labia majora 0.2989789674795678 0.0874170148107598 0.9303400452876622 1.0 1.0 13 Q9Y619,O75419,Q9H2M9,P16435,Q9UQE7 5 +Abnormal labia majora morphology 0.2989789674795678 0.0874170148107598 0.9303400452876622 1.0 1.0 13 Q9Y619,O75419,Q9H2M9,P16435,Q9UQE7 5 +Aplasia hypoplasia of the phalanges of the thumb 0.3084460314574905 0.0866088842177906 0.9309824038551292 1.0 1.0 10 Q8WVQ1,Q9BXW9 2 +Agitation 0.2956042639842495 0.0853444822603534 0.9319875287785302 1.0 1.0 34 O43464,P48449,Q13501,Q92804,Q15165,Q68CQ7,P35637,P42892,P42858,Q96QK1,Q01082 11 +Monotonic speech 0.3130223920713102 0.0832410459502611 0.9336598760223316 1.0 1.0 6 Q96QK1 1 +Abnormal morphology of the choroidal vasculature 0.4983722994969002 0.0818416242491851 0.934772655713148 1.0 1.0 2 P22413 1 +Choroidal neovascularization 0.4983722994969002 0.0818416242491851 0.934772655713148 1.0 1.0 2 P22413 1 +Retinal perforation 0.4983722994968993 0.0818416242491839 0.9347726557131488 1.0 1.0 2 P35222 1 +Lumbar scoliosis 0.3860272350503342 0.0814556186572603 0.9350796187222206 1.0 1.0 3 P27635,P21281 2 +Weak cry 0.3025869992419796 0.0813409653401789 0.9351707962760928 1.0 1.0 11 O60313,P06753 2 +Abnormal nerve conduction velocity 0.3006345081608014 0.0811459103636674 0.9353259148546428 1.0 1.0 45 Q99720,P07196,Q7Z406,Q9UBB4,O60333,Q9NR77,Q9GZY8,Q8TB36,O43681,P02545,P07602,P50570,O95831,Q71SY5 14 +Shyness 0.3843855494387381 0.0796662011541504 0.9365027415540934 1.0 1.0 3 Q15233 1 +Cutis laxa 0.2914646558368467 0.0780772965496116 0.937766566782227 1.0 1.0 31 Q8NCH0,Q9Y487,P38435 3 +Prominent antitragus 0.4930452796685489 0.0771247965357444 0.9385242669649771 1.0 1.0 2 Q9H2M9 1 +Bilateral cleft lip 0.3804026050917656 0.0754595234546412 0.9398491012825794 1.0 1.0 3 O15111,O60716 2 +Congenital bilateral hip dislocation 0.4891979875702948 0.0738920545391784 0.9410962781257112 1.0 1.0 2 Q9Y4R8 1 +Decerebrate rigidity 0.3354955143140408 0.0738794532289981 0.941106305109985 1.0 1.0 4 O43681 1 +Abnormality of the auditory canal 0.2843181994406019 0.0728349676661026 0.9419374446682104 1.0 1.0 26 P55011,P21281,O95202,O75419,Q9H9S5,P16435,Q9UQE7 7 +Peripheral hypomyelination 0.3771462403789232 0.0721602060796916 0.9424744135269196 1.0 1.0 3 Q8TB36,O60231 2 +Visual hallucinations 0.3188798243279327 0.0706112572983438 0.9437071507503868 1.0 1.0 5 Q96QK1 1 +Abnormality of the dorsal column of the spinal cord 0.3715216104203702 0.0667522449371844 0.9467789415812892 1.0 1.0 3 Q8WVX9,P54886 2 +Aplasia hypoplasia of the nasal bone 0.3712255772646599 0.0664776704522237 0.946997534775086 1.0 1.0 3 P10644,O14974 2 +Alveolar rhabdomyosarcoma 0.4761763835454357 0.0639881132008027 0.9489796917025904 1.0 1.0 2 Q14145 1 +Childhood onset 0.2951245197850072 0.0635774288791267 0.9493067045193166 1.0 1.0 38 P22830,O60220,Q9NR77,Q5JRX3,Q8WWV3,P50402,Q8WXH0 7 +Periventricular cysts 0.3037037037037073 0.0633577048892277 0.9494816661587496 1.0 1.0 6 Q01968,O95202,Q9Y285,P11177,O96028 5 +Aplasia hypoplasia of the nipples 0.2860012090262274 0.0629282698229283 0.949823623387418 1.0 1.0 17 O60826,Q9UQE7,Q96A33,P10586 4 +Akinesia 0.3008131661271513 0.0627331357548082 0.9499790108332182 1.0 1.0 10 Q96QK1,Q99567,Q14203 3 +Dilation of lateral ventricles 0.2838105922270074 0.0623034863973037 0.9503211521293924 1.0 1.0 27 Q9UID3,Q01105,Q71SY5,Q08209 4 +Abnormality of somatosensory evoked potentials 0.3134562678587029 0.0615098451511569 0.9509531739574836 1.0 1.0 5 Q9NQZ5,O60220 2 +Delirium 0.4720331459011597 0.061158534692482 0.9512329524049704 1.0 1.0 2 Q9UJS0 1 +Inappropriate antidiuretic hormone secretion 0.4702574726250451 0.059991424249137 0.952162464847406 1.0 1.0 2 Q13724 1 +Abnormality of central nervous system electrophysiology 0.2857671058039436 0.0599839184205165 0.9521684428664832 1.0 1.0 166 P55011,P48449,O95155,P40855,Q13813,O60220,Q9Y5P6,Q08209,Q9UBB4,Q9Y4W6,Q96A33,P03886,O60313,P21964,Q9BQE5,P50542,P42704,Q9BSJ2,Q9NSV4,O75381,Q9H3S7,O95202,Q15125,P15311,Q9Y5Y5,Q01082,Q13501,Q00577,Q2TAA5,P00403,Q05086,Q96N66,Q08J23,P13073,Q8IWS0,P21281,Q71SY5,Q13045,P07196,Q15067,Q8NB90,Q9GZY8,O43292,P07602,Q9H9S5,Q9UBX3,Q9H3H1 47 +Abnormality of female external genitalia 0.2961965396163426 0.0598693316764941 0.9522597058413338 1.0 1.0 41 O75381,O95155,P40855,O75419,Q15392,Q08J23,P50542,P16435,Q9UQE7,Q9Y5Y5 10 +Broad finger 0.2950176439371407 0.0590401590794983 0.952920121562927 1.0 1.0 39 P55011,Q9H3S7,Q96PZ0,Q08J23,Q13868,Q7LGA3,P42858,Q8N3R9,Q9UHX1 9 +Retinal fold 0.4684817993489281 0.0588511591103705 0.9530706599630894 1.0 1.0 2 P35222 1 +Epispadias 0.3013333333333369 0.0585812759420109 0.9532856247005368 1.0 1.0 6 P48651,Q9Y619,O75419,P53701,Q9NX14 5 +Focal dystonia 0.2734867183648101 0.0572639946022199 0.9543349014125606 1.0 1.0 21 Q99720,O60220,P35637 3 +Sparse and thin eyebrow 0.2907429562028859 0.0572450152929407 0.9543500199102803 1.0 1.0 12 Q96EK5,Q15125 2 +Joint contracture of the 5th finger 0.360568383658976 0.057243304158504 0.9543513829629088 1.0 1.0 3 Q9Y2B2,P49711 2 +Abnormality of renal excretion 0.302537566348323 0.0571867479275302 0.9543964345065858 1.0 1.0 8 O43772 1 +Abnormality of facial soft tissue 0.263083991291314 0.0565626517194544 0.9548935865002142 1.0 1.0 126 P40855,Q9Y5P6,O60313,Q03252,P50542,P50570,O00170,Q9Y4P3,Q15056,O75381,P28070,Q8NFH4,P31749,P51812,O00429,Q9BQT8,Q8N1F7,O43707,Q9Y5Y5,Q01082,Q9UHX1,Q13501,Q14203,Q00577,Q13555,Q969G3,P16435,O60826,P49815,Q15437,P35609,P07196,P06753,Q14C86,P02545,P43246,Q9H9S5,O75844,O15020,Q96QK1,Q01433 41 +Progressive muscle weakness 0.2898314865570285 0.0540642703181643 0.9568839587497224 1.0 1.0 14 O75381,P40855,P06753,P50542 4 +Abnormal urine hormone level 0.4598993785143589 0.0537071373586003 0.9571684962214508 1.0 1.0 2 P10644 1 +Increased urinary cortisol level 0.4598993785143589 0.0537071373586003 0.9571684962214508 1.0 1.0 2 P10644 1 +Small anterior fontanelle 0.4593074874223227 0.0533741869531779 0.9574337717159136 1.0 1.0 2 Q9Y619 1 +Abnormality of the thoracic cavity 0.2881793480190055 0.0521202928702497 0.958432843568546 1.0 1.0 15 Q01844,P31749 2 +Absent septum pellucidum 0.293851170769796 0.0517669928774231 0.95871435613995 1.0 1.0 39 P55011,O95202,Q9UBB6,Q2M1P5,Q96N66,Q15392,P15311,Q08J23,Q9H9S5,Q71SY5 10 +Aplasia hypoplasia of the lungs 0.2890150086952101 0.0515818360424833 0.9588618928085768 1.0 1.0 33 Q7Z4L5,O95202,O75419,P98175,O75844,Q99567,O96000,Q8NCM8,Q14739 9 +Abnormal right ventricle morphology 0.3002143934881954 0.0515272609230471 0.9589053796241728 1.0 1.0 8 P06753 1 +Focal motor status epilepticus 0.4545723586860102 0.0508081667430851 0.9594783831643235 1.0 1.0 2 Q8TAB3 1 +Abnormal thumb morphology 0.2584868296622901 0.0507965555110724 0.9594876356396076 1.0 1.0 119 P55011,Q2M1P5,P42892,Q03252,P42858,Q9UQE7,Q9H3S7,Q15233,Q9H6K4,Q8N0X7,Q9UHX1,Q86XL3,Q96PZ0,Q8NCH0,P25054,Q08J23,Q13868,Q8NCM8,Q71SY5,Q8WVQ1,Q9UGU0,P46783,Q7LGA3,Q9BXW9,Q8N3R9,Q9UPP1 26 +Truncal titubation 0.4510210121337754 0.0489946932249541 0.9609235250554796 1.0 1.0 2 Q5T8D3 1 +Abnormal venous morphology 0.2839926589049971 0.0487423625183036 0.9611246155711356 1.0 1.0 29 Q92990,P31749,Q9Y487,P21964,Q71SY5 5 +Hypermetric saccades 0.4483575022195982 0.0476950926615683 0.9619592451425752 1.0 1.0 2 P18887 1 +Smooth muscle antibody positivity 0.4477656111275605 0.0474131932562307 0.9621839141485258 1.0 1.0 2 Q96J02 1 +Bilateral ptosis 0.2880015115686382 0.0471078331218609 0.9624272843419674 1.0 1.0 14 O75306,Q9UNW9,O00429,O60313,Q5T8D3,P21281 6 +Glossitis 0.4445102101213463 0.0459067153265824 0.96338460176538 1.0 1.0 2 O15460 1 +Gastrointestinal infarctions 0.4445102101213463 0.0459067153265824 0.96338460176538 1.0 1.0 2 O15460 1 +Recurrent pharyngitis 0.4445102101213463 0.0459067153265824 0.96338460176538 1.0 1.0 2 O15460 1 +Enthesitis 0.4445102101213456 0.0459067153265821 0.9633846017653802 1.0 1.0 2 P22413 1 +Abnormal sacroiliac joint morphology 0.4445102101213456 0.0459067153265821 0.9633846017653802 1.0 1.0 2 P22413 1 +Abnormal circulating glutamine family amino acid concentration 0.2968474271118552 0.0451371543382008 0.9639979867097042 1.0 1.0 9 Q9P0J1 1 +Abnormal exteroceptive sensation 0.2951597472152745 0.0450468251280238 0.964069985757266 1.0 1.0 52 P07196,Q8NCH0,Q9NR77,Q9NZ08,P61978,O95831,Q9H6K4 7 +Abnormal fingertip morphology 0.2878102128470653 0.0446152663868504 0.9644139739598724 1.0 1.0 33 P55011,Q9H3S7,Q96PZ0,O75844,Q7LGA3,P42858,P55795,Q8N3R9 8 +Abnormality of the extraocular muscles 0.3404381290704531 0.0430405419420157 0.9656692159853152 1.0 1.0 3 P43243,Q13509 2 +Vitritis 0.3398460627590293 0.0426823994471978 0.9659547099891688 1.0 1.0 3 P04439,P53701 2 +Recurrent skin infections 0.2868912537920826 0.0419982079107902 0.9665001267382384 1.0 1.0 13 Q8NCH0 1 +Tube feeding 0.2729918868410308 0.0416919685700434 0.9667442565485443 1.0 1.0 74 P55011,Q99720,Q9H3S7,P06753,Q08209,O00429,Q9GZY8,P35637,Q96EY7,P15311,Q01105,P61978,Q08J23,P42704,Q15233,Q71SY5,Q9UHX1 17 +Broad alveolar ridges 0.3378831754396336 0.0415179754418415 0.9668829628785782 1.0 1.0 3 P21281 1 +Abnormality of the musculature of the limbs 0.2853546231430179 0.041336646964641 0.9670275179732104 1.0 1.0 168 Q7RTS9,Q08209,Q9Y4W6,O60313,Q8WXH0,P00846,Q15125,P31749,O00429,O60333,Q9NR77,Q8TD16,O14979,Q14739,Q8IY17,Q13501,Q13126,Q9Y487,Q2TAA5,P35609,Q99720,O75298,P07196,P06753,Q7Z406,Q15067,P46783,Q9H9S5,P50402 29 +Skin tags 0.2720676165747481 0.0410610644882793 0.9672472144460592 1.0 1.0 22 Q9UHX1 1 +Flattened femoral epiphysis 0.4303048239124079 0.0401550613468372 0.967969504560858 1.0 1.0 2 Q9NUQ7 1 +Multiple cafe au lait spots 0.2853569045511223 0.0385360676090179 0.96926027503692 1.0 1.0 12 Q15437,Q9BXW9,P31749 3 +Elevated tissue non specific alkaline phosphatase 0.3300769686204845 0.0372256007803707 0.9703051262846156 1.0 1.0 3 Q13043,P22413 2 +Abnormality of dna repair 0.3039178029744147 0.0370160498035124 0.9704722086177572 1.0 1.0 4 P18074,Q9BXW9 2 +Ectopia pupillae 0.303523837725786 0.0366441565066163 0.9707687353548836 1.0 1.0 4 O96028,P61586,O95202 3 +Bloody diarrhea 0.2916146777821409 0.0359827224869753 0.9712961354905922 1.0 1.0 10 P25054 1 +Impaired distal vibration sensation 0.2891851851851881 0.0358888025600729 0.971371024379607 1.0 1.0 6 Q06787,P55072,P20700,Q96RR1,P54886 5 +Megaloblastic anemia 0.2933108537985781 0.0354495857916018 0.9717212457924752 1.0 1.0 8 O76024,Q99707,P00374 3 +Low back pain 0.4152116010654103 0.035354081264559 0.9717973996436822 1.0 1.0 2 Q8WVX9 1 +Hypertensive crisis 0.2915375132310667 0.0345018320711634 0.9724769814380052 1.0 1.0 7 O00192,P21964 2 +Head banging 0.4119562000591983 0.0344749033123347 0.9724984547044556 1.0 1.0 2 P28482 1 +Irregular femoral epiphysis 0.3011548711874379 0.0344509775795545 0.9725175333440864 1.0 1.0 4 P50542,P26373,Q9NUQ7 3 +Cystic renal dysplasia 0.4101805267830786 0.0340168720230047 0.972863696558258 1.0 1.0 2 P23786 1 +Abnormal brainstem morphology 0.243052492959449 0.0334201677683396 0.9733395270914204 1.0 1.0 96 Q13813,P31749,O00429,Q9UID3,P03886,O60313,Q86Y39,Q9H9S5,O96000,P07942,Q96EK5,O43676,O95831 13 +Abnormal brain choline level by mrs 0.3198778539504783 0.0323838752857704 0.974165921402006 1.0 1.0 3 P07602 1 +Abnormal brain n acetyl aspartate level by mrs 0.3198778539504783 0.0323838752857704 0.974165921402006 1.0 1.0 3 P07602 1 +Reduced brain n acetyl aspartate level by mrs 0.3198778539504783 0.0323838752857704 0.974165921402006 1.0 1.0 3 P07602 1 +Pterygium 0.2871670436580422 0.0313259973727497 0.9750095576736408 1.0 1.0 11 Q96AY3 1 +Female infertility 0.3950873039360824 0.0306859288122897 0.975520013060013 1.0 1.0 2 Q15645 1 +Abnormal cerebral artery morphology 0.2834905482755258 0.0304316196240248 0.9757228277142572 1.0 1.0 14 P38435,Q9Y3Z3 2 +Progressive flexion contractures 0.3936075762059856 0.0304091775058586 0.9757407256505564 1.0 1.0 2 Q12904 1 +Delayed ossification of carpal bones 0.3859129920094772 0.0290975496292854 0.97678679008447 1.0 1.0 2 Q9NUQ7 1 +Central hypoventilation 0.2879078060137559 0.0274475737690699 0.9781027541448286 1.0 1.0 7 P06753,Q14203 2 +Short upper lip 0.2841856687157206 0.0274120144963773 0.9781311156679804 1.0 1.0 6 Q01433 1 +Congenital craniofacial dysostosis 0.371115714708503 0.0271072388676634 0.9783742011020764 1.0 1.0 2 P10644 1 +Absent distal phalanges 0.3711157147085008 0.0271072388676631 0.9783742011020766 1.0 1.0 2 O15111 1 +Scaling skin 0.2883385232070349 0.0269994646849685 0.978460160996375 1.0 1.0 10 O75844 1 +Abnormality of the middle phalanges of the toes 0.3604616750517978 0.0260356096404925 0.9792289356845376 1.0 1.0 2 Q9ULC3 1 +Sclerotic vertebral endplates 0.3589819473217002 0.025907138714033 0.9793314060886004 1.0 1.0 2 P22413 1 +Distal upper limb muscle weakness 0.2889584741651947 0.0258840803283792 0.9793497978508784 1.0 1.0 8 Q13501,Q9Y5P6 2 +Abnormality of the voice 0.2720959736810731 0.0257134039879883 0.9794859325561314 1.0 1.0 146 P55011,Q9BTV4,Q13409,Q9Y5P6,P03886,O60313,P21964,O00170,P42858,Q8WXH0,Q9Y4P3,Q15056,Q9UQE7,Q9NZN8,P00846,Q9H3S7,O60333,Q9NR77,Q8TB36,Q96DF8,Q15233,Q8N0X7,Q01082,Q96PZ0,Q14203,Q9Y3Z3,P07237,Q9Y487,O75208,Q96HY6,Q13045,Q9UGU0,Q6DKK2,P06753,Q7Z406,Q4J6C6,P02545,Q9H9S5,O75844,Q7LGA3,P50402,Q96QK1,Q8N3R9,Q9UPP1 44 +Abnormal magnesium concentration 0.2879063177327925 0.0254730334390289 0.9796776577040558 1.0 1.0 5 P05023 1 +Shallow anterior chamber 0.3533589819473293 0.0254594742200986 0.979688472887942 1.0 1.0 2 Q9Y2B2 1 +Hyperkeratotic papule 0.344776561112763 0.0248880090016526 0.980144291703564 1.0 1.0 2 Q9H488 1 +Ovotestis 0.3397454868304314 0.024608163210886 0.980367507971842 1.0 1.0 2 P53701 1 +Abnormal vertebral morphology 0.2539987904142145 0.0246035888040113 0.9803711567157308 1.0 1.0 115 Q7RTS9,O00170,Q10713,Q5JRA6,Q15125,P31749,Q96AY3,Q32P28,Q8WXW3,Q14739,P00813,Q9UHX1,Q8NCH0,O75845,P25054,P61978,P16435,Q8NCM8,O60826,O95831,Q96HY6,Q8WVQ1,O75718,Q9H9S5 24 +Spastic hyperactive bladder 0.2823703703703737 0.0244571587346344 0.9804879558606184 1.0 1.0 6 Q6PI48,Q04637,O75165,Q96QK1,Q6Y7W6 5 +Macroscopic hematuria 0.3344184670020796 0.0243507041109219 0.9805728690723884 1.0 1.0 2 P00492 1 +Uric acid nephrolithiasis 0.3344184670020796 0.0243507041109219 0.9805728690723884 1.0 1.0 2 P00492 1 +Hyperlordosis 0.2916684208545208 0.02425123011998 0.980652214402294 1.0 1.0 54 Q9BTV4,Q7RTS9,Q8WVQ1,P06753,Q9Y5P6,P22626,Q8TD16,P02545,Q9H9S5,P55795,P50402,P50570,Q8WXH0,Q9Y4P3,Q15056,Q96HY6 16 +Localized osteoporosis 0.3317549570879037 0.024235591874186 0.9806646882509238 1.0 1.0 2 P57740 1 +Elevated alkaline phosphatase of bone origin 0.3299792838117865 0.0241635352547133 0.9807221642831034 1.0 1.0 2 P22413 1 +Decreased cd4 cd8 ratio 0.2936648904677283 0.0233557419872062 0.981366508143748 1.0 1.0 3 P17812,Q9H0U3 2 +Abnormal midbrain morphology 0.287767512674756 0.0233435862594525 0.981376204367664 1.0 1.0 8 Q10713,Q8WXW3 2 +Eeg with irregular generalized spike and wave complexes 0.2906185261911894 0.0232584416027457 0.9814441215347818 1.0 1.0 2 Q9NQZ5 1 +Abnormal cranial nerve physiology 0.2656495279665796 0.0231631028377214 0.9815201703753784 1.0 1.0 77 O75381,O95155,P07196,P31749,Q9NR77,Q9NZ08,Q9H9S5,Q9UHX1 8 +Rectal prolapse 0.2863254965853711 0.0216229513606932 0.9827487252721928 1.0 1.0 10 Q9Y4P3,Q15056,Q08J23 3 +Abnormal b cell subset distribution 0.2849174353697772 0.0212530633982691 0.9830437853541052 1.0 1.0 3 P17812 1 +Gastric ulcer 0.2821195973949026 0.0206608878042912 0.983516169365226 1.0 1.0 3 Q8N5K1,O76024 2 +Erlenmeyer flask deformity of the femurs 0.2822031388806575 0.0194382838704325 0.9844914700590364 1.0 1.0 4 P07602,P51798,Q9NZJ7 3 +Poor eye contact 0.2912932011189401 0.01924085426852 0.9846489666338876 1.0 1.0 45 P56556,P03886,Q9H0W8,O96000,O43676,Q86Y39,Q9UHX1 7 +Neoplasm of the tongue 0.2847539490812056 0.0175016166198313 0.9860364431684844 1.0 1.0 10 Q2M1P5,Q8NCM8,P31749 3 +Macular atrophy 0.2824540604623616 0.017382543773499 0.9861314351035126 1.0 1.0 7 P04439,Q8WWY3,P54577,Q92620,Q9NQ48,P19367 6 +Abnormal circulating albumin concentration 0.2829500643498187 0.0172156019400541 0.9862646154856828 1.0 1.0 33 Q14C86,O43707,Q8N1F7,O95470,Q6PGP7 5 +Macrovesicular hepatic steatosis 0.276858360935368 0.0158823945123656 0.98732821537615 1.0 1.0 6 Q96AX1,P23786 2 +Abnormal number of permanent teeth 0.2791627186865945 0.0156205205471767 0.987537134650331 1.0 1.0 5 Q9ULC3,Q14696 2 +Stereotypy 0.2667333370021063 0.0153959823710723 0.9877162686512952 1.0 1.0 76 P55011,O95155,Q08209,Q9UNW9,Q03164,O95202,P15311,Q01105,P55795,Q01082,Q9UHX1,Q13501,Q05086,Q96N66,Q9BXJ9,Q08J23,P49815,Q71SY5,Q13045,Q8NB90 20 +Chronic diarrhea 0.2739544761918269 0.0120307439691045 0.9904010866885042 1.0 1.0 17 Q9BT22,P00813,Q13277,Q96A33 4 +Hypomimic face 0.2826215895610934 0.0106165193167285 0.9915294022688752 1.0 1.0 9 P12235,P35270,Q9Y263,Q96RR1,Q04637,O75165,Q96QK1,Q6Y7W6 8 +Abnormal elasticity of skin 0.2858190027821178 0.0104094455078593 0.9916946141335324 1.0 1.0 61 Q8NCH0,Q13126,Q9Y487,Q9NWM8,P38435,Q9UHX1 6 +Cardiovascular calcification 0.2815847444355506 0.0093938428610357 0.9925049080479036 1.0 1.0 10 O75844 1 +Spastic paraparetic gait 0.2611785608528232 0.0074888484112978 0.9940248193253454 1.0 1.0 4 Q12756,Q01433,P34897 3 +Aplasia hypoplasia of the thymus 0.2728067400862229 0.0074772018721865 0.9940341116589202 1.0 1.0 17 Q6PGP7,P21964,P00813 3 +Dysuria 0.2787648527465353 0.0052063381503451 0.9958459619380586 1.0 1.0 8 O76024,Q8N0X7,O00170 3 +Renal tubular atrophy 0.2668838862559177 0.0037610020325752 0.9969991616196064 1.0 1.0 5 Q8WUM0,Q12965,Q96AX1,P57740 4 +Absent thumbnail 0.2503141507187322 0.0029521644677965 0.997644516971642 1.0 1.0 4 P21281 1 +Abnormal pulmonary thoracic imaging finding 0.2601742340215728 0.0014209563651803 0.99886624123618 1.0 1.0 20 P49815,Q9NZ08 2 diff --git a/msigdb_hp/selections.json b/msigdb_hp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..f4922b761c40b1eeb96987ba19f2f6cefe101403 --- /dev/null +++ b/msigdb_hp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["11 pairs of ribs", "2 3 finger syndactyly", "2 3 toe cutaneous syndactyly", "2 3 toe syndactyly", "3 4 finger syndactyly", "3 methylglutaconic aciduria", "4 5 toe syndactyly", "Abdominal aortic aneurysm", "Abdominal distention", "Abdominal obesity", "Abdominal pain", "Abdominal wall muscle weakness", "Abducens palsy", "Abnormal 2nd finger morphology", "Abnormal 3rd finger morphology", "Abnormal 5th finger morphology", "Abnormal 5th finger phalanx morphology", "Abnormal abdomen morphology", "Abnormal acetabulum morphology", "Abnormal activity of mitochondrial respiratory chain", "Abnormal adipose tissue morphology", "Abnormal aggressive impulsive or violent behavior", "Abnormal aldolase level", "Abnormal anatomic location of the heart", "Abnormal anterior chamber morphology", "Abnormal anterior eye segment morphology", "Abnormal anterior horn cell morphology", "Abnormal aortic arch morphology", "Abnormal aortic morphology", "Abnormal aortic valve cusp morphology", "Abnormal aortic valve morphology", "Abnormal aortic valve physiology", "Abnormal arachnoid mater morphology", "Abnormal arm span", "Abnormal arterial physiology", "Abnormal astrocyte morphology", "Abnormal atrial arrangement", "Abnormal atrioventricular conduction", "Abnormal atrioventricular valve morphology", "Abnormal atrioventricular valve physiology", "Abnormal auditory evoked potentials", "Abnormal autonomic nervous system physiology", "Abnormal b cell morphology", "Abnormal b cell subset distribution", "Abnormal basal ganglia mri signal intensity", "Abnormal biliary tract morphology", "Abnormal bleeding", "Abnormal blistering of the skin", "Abnormal blood carbon dioxide level", "Abnormal blood chloride concentration", "Abnormal blood gas level", "Abnormal blood glucose concentration", "Abnormal blood inorganic cation concentration", "Abnormal blood ion concentration", "Abnormal blood monovalent inorganic cation concentration", "Abnormal blood phosphate concentration", "Abnormal blood potassium concentration", "Abnormal blood sodium concentration", "Abnormal blood transition element cation concentration", "Abnormal blood zinc concentration", "Abnormal bone structure", "Abnormal bowel sounds", "Abnormal brain choline level by mrs", "Abnormal brain lactate level by mrs", "Abnormal brain n acetyl aspartate level by mrs", "Abnormal brain positron emission tomography", "Abnormal brainstem morphology", "Abnormal brainstem mri signal intensity", "Abnormal branching pattern of the aortic arch", "Abnormal breath sound", "Abnormal bronchoalveolar lavage fluid morphology", "Abnormal bronchus morphology", "Abnormal bronchus physiology", "Abnormal c peptide level", "Abnormal c reactive protein level", "Abnormal calcification of the carpal bones", "Abnormal calcium phosphate regulating hormone level", "Abnormal cardiac atrium morphology", "Abnormal cardiac exercise stress test", "Abnormal cardiac septum morphology", "Abnormal cardiac test", "Abnormal cardiac ventricle morphology", "Abnormal cardiac ventricular function", "Abnormal cardiomyocyte morphology", "Abnormal carotid artery morphology", "Abnormal cartilage morphology", "Abnormal caudate nucleus morphology", "Abnormal cd4 cd8 ratio", "Abnormal cell morphology", "Abnormal cell proliferation", "Abnormal cellular composition of bronchoalveolar fluid", "Abnormal cellular phenotype", "Abnormal central sensory function", "Abnormal cerebellar vermis morphology", "Abnormal cerebral artery morphology", "Abnormal cerebral cortex morphology", "Abnormal cerebral vascular morphology", "Abnormal cerebral vein morphology", "Abnormal cerebral ventricle morphology", "Abnormal cerebrospinal fluid metabolite concentration", "Abnormal cervical curvature", "Abnormal cervical spine morphology", "Abnormal chorioretinal morphology", "Abnormal choroid morphology", "Abnormal choroid plexus morphology", "Abnormal chromosome morphology", "Abnormal ciliary body morphology", "Abnormal circulating acetylcarnitine concentration", "Abnormal circulating albumin concentration", "Abnormal circulating aldosterone", "Abnormal circulating amino acid concentration", "Abnormal circulating amylase level", "Abnormal circulating androgen level", "Abnormal circulating apolipoprotein concentration", "Abnormal circulating arginine concentration", "Abnormal circulating aromatic amino acid concentration", "Abnormal circulating aspartate family amino acid concentration", "Abnormal circulating bilirubin concentration", "Abnormal circulating branched chain amino acid concentration", "Abnormal circulating carbohydrate concentration", "Abnormal circulating carboxylic acid concentration", "Abnormal circulating ceruloplasmin concentration", "Abnormal circulating cholesterol concentration", "Abnormal circulating citrulline concentration", "Abnormal circulating copper concentration", "Abnormal circulating creatinine concentration", "Abnormal circulating dehydroepiandrosterone concentration", "Abnormal circulating dicarboxylic acid concentration", "Abnormal circulating estrogen level", "Abnormal circulating fatty acid anion concentration", "Abnormal circulating fatty acid concentration", "Abnormal circulating ferritin concentration", "Abnormal circulating follicle stimulating hormone concentration", "Abnormal circulating free fatty acid concentration", "Abnormal circulating gaba concentration", "Abnormal circulating glutamine concentration", "Abnormal circulating glutamine family amino acid concentration", "Abnormal circulating glycine concentration", "Abnormal circulating gonadotropin concentration", "Abnormal circulating hormone concentration", "Abnormal circulating iga level", "Abnormal circulating ige level", "Abnormal circulating igg level", "Abnormal circulating igm level", "Abnormal circulating inhibin level", "Abnormal circulating lipid concentration", "Abnormal circulating long chain fatty acid concentration", "Abnormal circulating metabolite concentration", "Abnormal circulating methionine concentration", "Abnormal circulating monocarboxylic acid cocentration", "Abnormal circulating nitrogen compound concentration", "Abnormal circulating non proteinogenic amino acid concentration", "Abnormal circulating nucleobase concentration", "Abnormal circulating phenylalanine concentration", "Abnormal circulating porphyrin concentration", "Abnormal circulating progesterone level", "Abnormal circulating proline concentration", "Abnormal circulating protein concentration", "Abnormal circulating proteinogenic amino acid concentration", "Abnormal circulating proteinogenic amino acid derivative concentration", "Abnormal circulating pyruvate family amino acid concentration", "Abnormal circulating renin", "Abnormal circulating serine concentration", "Abnormal circulating serine family amino acid concentration", "Abnormal circulating sex hormone concentration", "Abnormal circulating sulfur amino acid concentration", "Abnormal circulating tyrosine concentration", "Abnormal clavicle morphology", "Abnormal cns myelination", "Abnormal coccyx morphology", "Abnormal cochlea morphology", "Abnormal conjugate eye movement", "Abnormal conjunctiva morphology", "Abnormal connection of the cardiac segments", "Abnormal consumption behavior", "Abnormal conus terminalis morphology", "Abnormal cornea morphology", "Abnormal corneal epithelium morphology", "Abnormal coronary artery morphology", "Abnormal coronary sinus morphology", "Abnormal corpus callosum morphology", "Abnormal corpus striatum morphology", "Abnormal cortical bone morphology", "Abnormal cortical gyration", "Abnormal cranial nerve morphology", "Abnormal cranial nerve physiology", "Abnormal cry", "Abnormal csf carboxylic acid concentration", "Abnormal csf metabolite level", "Abnormal csf protein level", "Abnormal csf pyruvate family amino acid concentration", "Abnormal cutaneous elastic fiber morphology", "Abnormal delayed hypersensitivity skin test", "Abnormal delivery", "Abnormal dense granules", "Abnormal dental pulp morphology", "Abnormal dental root morphology", "Abnormal dentate nucleus morphology", "Abnormal dentin morphology", "Abnormal dermatoglyphics", "Abnormal dermoepidermal junction morphology", "Abnormal diaphysis morphology", "Abnormal distal phalanx morphology of finger", "Abnormal dlco", "Abnormal drinking behavior", "Abnormal duodenum morphology", "Abnormal dura mater morphology", "Abnormal eating behavior", "Abnormal echocardiogram", "Abnormal elasticity of skin", "Abnormal electrophysiology of sinoatrial node origin", "Abnormal electroretinogram", "Abnormal emotion affect behavior", "Abnormal enchondral ossification", "Abnormal endocardium morphology", "Abnormal endocrine physiology", "Abnormal energy expenditure", "Abnormal enzyme coenzyme activity", "Abnormal eosinophil morphology", "Abnormal epidermal morphology", "Abnormal epiglottis morphology", "Abnormal epiphyseal ossification", "Abnormal epiphysis morphology of the phalanges of the hand", "Abnormal erythrocyte enzyme level", "Abnormal erythrocyte morphology", "Abnormal erythrocyte physiology", "Abnormal erythrocyte sedimentation rate", "Abnormal esophagus morphology", "Abnormal esophagus physiology", "Abnormal external genitalia", "Abnormal exteroceptive sensation", "Abnormal eyebrow morphology", "Abnormal eyelash morphology", "Abnormal eyelid morphology", "Abnormal eyelid physiology", "Abnormal facial expression", "Abnormal facial shape", "Abnormal factor ix activity", "Abnormal fallopian tube morphology", "Abnormal fear anxiety related behavior", "Abnormal female reproductive system physiology", "Abnormal femoral head morphology", "Abnormal femoral neck head morphology", "Abnormal femoral neck morphology", "Abnormal finger flexion creases", "Abnormal finger phalanx morphology", "Abnormal fingernail morphology", "Abnormal fingertip morphology", "Abnormal foot bone ossification", "Abnormal foramen magnum morphology", "Abnormal forearm bone morphology", "Abnormal form of the vertebral bodies", "Abnormal foveal morphology", "Abnormal full field electroretinogram", "Abnormal fundus autofluorescence imaging", "Abnormal gallbladder morphology", "Abnormal gastrointestinal motility", "Abnormal glial cell morphology", "Abnormal globus pallidus morphology", "Abnormal glomerular basement membrane morphology", "Abnormal glomerular filtration rate", "Abnormal glomerular mesangial cellularity", "Abnormal glomerular mesangium morphology", "Abnormal glucose homeostasis", "Abnormal glycosylation", "Abnormal granulocyte count", "Abnormal granulocytopoietic cell morphology", "Abnormal greater sciatic notch morphology", "Abnormal growth hormone level", "Abnormal hair laboratory examination", "Abnormal hair morphology", "Abnormal hair pattern", "Abnormal hair quantity", "Abnormal hair whorl", "Abnormal hand bone ossification", "Abnormal hand morphology", "Abnormal hdl cholesterol concentration", "Abnormal head movements", "Abnormal heart rate variability", "Abnormal heart sound", "Abnormal heart valve morphology", "Abnormal heart valve physiology", "Abnormal hemidiaphragm morphology", "Abnormal hemoglobin", "Abnormal hemoglobin concentration", "Abnormal hepatic iron concentration", "Abnormal humerus morphology", "Abnormal hypothalamus morphology", "Abnormal hypothalamus physiology", "Abnormal ileum morphology", "Abnormal iliac wing morphology", "Abnormal ilium morphology", "Abnormal immune system morphology", "Abnormal incisor morphology", "Abnormal inflammatory response", "Abnormal insulin level", "Abnormal internal carotid artery morphology", "Abnormal internal genitalia", "Abnormal intestine morphology", "Abnormal intraocular pressure", "Abnormal involuntary eye movements", "Abnormal iris pigmentation", "Abnormal jaw morphology", "Abnormal jejunum morphology", "Abnormal joint morphology", "Abnormal labia majora morphology", "Abnormal labia minora morphology", "Abnormal labia morphology", "Abnormal lacrimal duct morphology", "Abnormal lacrimal gland morphology", "Abnormal lactate dehydrogenase level", "Abnormal large intestine morphology", "Abnormal large intestine physiology", "Abnormal larynx morphology", "Abnormal larynx physiology", "Abnormal lateral ventricle morphology", "Abnormal ldl cholesterol concentration", "Abnormal left atrium morphology", "Abnormal left ventricle morphology", "Abnormal left ventricular outflow tract morphology", "Abnormal length of corpus callosum", "Abnormal leukocyte count", "Abnormal leukocyte physiology", "Abnormal levels of alpha fetoprotein", "Abnormal libido", "Abnormal light and dark adapted electroretinogram", "Abnormal lip morphology", "Abnormal liver morphology", "Abnormal liver parenchyma morphology", "Abnormal liver physiology", "Abnormal localization of kidney", "Abnormal location of ears", "Abnormal lower limb bone morphology", "Abnormal lower motor neuron morphology", "Abnormal lumbar spine morphology", "Abnormal lung development", "Abnormal lung lobation", "Abnormal lymphatic vessel morphology", "Abnormal lymphocyte morphology", "Abnormal macrophage morphology", "Abnormal macroscopic urine appearance", "Abnormal macular morphology", "Abnormal magnesium concentration", "Abnormal male reproductive system physiology", "Abnormal mandibular ramus morphology", "Abnormal mast cell morphology", "Abnormal mean corpuscular hemoglobin concentration", "Abnormal mean corpuscular volume", "Abnormal megakaryocyte morphology", "Abnormal meningeal morphology", "Abnormal metabolic brain imaging by mrs", "Abnormal metabolism", "Abnormal metacarpal morphology", "Abnormal metaphyseal trabeculation", "Abnormal metatarsal morphology", "Abnormal midbrain morphology", "Abnormal middle phalanx morphology of the hand", "Abnormal mitochondria in muscle tissue", "Abnormal mitochondrial morphology", "Abnormal mitochondrial number", "Abnormal mitochondrial shape", "Abnormal mitral valve physiology", "Abnormal monocyte morphology", "Abnormal morphology of myocardial trabeculae", "Abnormal morphology of the abdominal musculature", "Abnormal morphology of the choroidal vasculature", "Abnormal morphology of the conjunctival vasculature", "Abnormal morphology of the great vessels", "Abnormal morphology of the limbic system", "Abnormal morphology of the musculature of the neck", "Abnormal morphology of the olfactory bulb", "Abnormal morphology of the radius", "Abnormal motor evoked potentials", "Abnormal motor nerve conduction velocity", "Abnormal muscle fiber alpha dystroglycan", "Abnormal muscle fiber morphology", "Abnormal muscle fiber protein expression", "Abnormal muscle fiber type distribution", "Abnormal muscle glycogen content", "Abnormal myelination", "Abnormal myeloid cell morphology", "Abnormal myeloid leukocyte morphology", "Abnormal myocardium morphology", "Abnormal nasal base", "Abnormal nasal bridge morphology", "Abnormal nasal mucosa morphology", "Abnormal nasolacrimal system morphology", "Abnormal natural killer cell morphology", "Abnormal natural killer cell physiology", "Abnormal nephron morphology", "Abnormal nerve conduction velocity", "Abnormal nervous system electrophysiology", "Abnormal neural tube morphology", "Abnormal neuron morphology", "Abnormal neutrophil count", "Abnormal nipple morphology", "Abnormal number of erythroid precursors", "Abnormal number of granulocyte precursors", "Abnormal number of incisors", "Abnormal number of permanent teeth", "Abnormal number of teeth", "Abnormal odontoid tissue morphology", "Abnormal optical coherence tomography", "Abnormal oral frenulum morphology", "Abnormal oral mucosa morphology", "Abnormal oral physiology", "Abnormal ossification involving the femoral head and neck", "Abnormal ovarian morphology", "Abnormal ovarian physiology", "Abnormal palate morphology", "Abnormal palmar dermatoglyphics", "Abnormal pancreas morphology", "Abnormal pancreas size", "Abnormal paranasal sinus morphology", "Abnormal parietal bone morphology", "Abnormal parotid gland morphology", "Abnormal patella morphology", "Abnormal pattern of respiration", "Abnormal pelvis bone morphology", "Abnormal pelvis bone ossification", "Abnormal penis morphology", "Abnormal pericardium morphology", "Abnormal perifollicular morphology", "Abnormal peripheral action potential amplitude", "Abnormal peripheral myelination", "Abnormal peripheral nervous system morphology", "Abnormal peripheral nervous system physiology", "Abnormal peristalsis", "Abnormal periventricular white matter morphology", "Abnormal phalangeal joint morphology of the hand", "Abnormal pharynx morphology", "Abnormal pigmentation of the oral mucosa", "Abnormal pineal morphology", "Abnormal placenta morphology", "Abnormal placental membrane morphology", "Abnormal placental size", "Abnormal platelet aggregation", "Abnormal platelet function", "Abnormal platelet granules", "Abnormal platelet morphology", "Abnormal platelet volume", "Abnormal pleura morphology", "Abnormal pons morphology", "Abnormal posterior segment imaging", "Abnormal posturing", "Abnormal pr interval", "Abnormal preputium morphology", "Abnormal prolactin level", "Abnormal proportion of cd4 positive t cells", "Abnormal proportion of cd8 positive t cells", "Abnormal proportion of class switched memory b cells", "Abnormal proportion of double negative alpha beta regulatory t cell", "Abnormal prostate morphology", "Abnormal protein glycosylation", "Abnormal protein o linked glycosylation", "Abnormal proximal phalanx morphology of the hand", "Abnormal pulmonary interstitial morphology", "Abnormal pulmonary thoracic imaging finding", "Abnormal pulmonary valve morphology", "Abnormal pulmonary valve physiology", "Abnormal pulse", "Abnormal pupil morphology", "Abnormal pupillary function", "Abnormal pupillary light reflex", "Abnormal pyramidal sign", "Abnormal qrs complex", "Abnormal qt interval", "Abnormal rapid eye movement sleep", "Abnormal rectum morphology", "Abnormal reflex", "Abnormal renal collecting system morphology", "Abnormal renal cortex morphology", "Abnormal renal corticomedullary differentiation", "Abnormal renal echogenicity", "Abnormal renal insterstitial morphology", "Abnormal renal medulla morphology", "Abnormal renal morphology", "Abnormal renal pelvis morphology", "Abnormal renal physiology", "Abnormal renal resorption", "Abnormal renal tubule morphology", "Abnormal renal vascular morphology", "Abnormal respiratory motile cilium morphology", "Abnormal respiratory motile cilium physiology", "Abnormal respiratory system morphology", "Abnormal response to acth stimulation test", "Abnormal response to endocrine stimulation test", "Abnormal response to insulin tolerance test", "Abnormal reticulocyte morphology", "Abnormal retinal artery morphology", "Abnormal retinal morphology", "Abnormal retinal vascular morphology", "Abnormal rib cage morphology", "Abnormal rib ossification", "Abnormal right atrium morphology", "Abnormal right ventricle morphology", "Abnormal right ventricular function", "Abnormal saccadic eye movements", "Abnormal sacroiliac joint morphology", "Abnormal sacrum morphology", "Abnormal salivary gland morphology", "Abnormal sarcomere morphology", "Abnormal scalp morphology", "Abnormal scapula morphology", "Abnormal sclera morphology", "Abnormal scrotal rugation", "Abnormal sella turcica morphology", "Abnormal sensory nerve conduction velocity", "Abnormal serum insulin like growth factor 1 level", "Abnormal serum interferon level", "Abnormal serum interleukin level", "Abnormal serum iron concentration", "Abnormal sex determination", "Abnormal shape of the frontal region", "Abnormal shape of the occiput", "Abnormal shape of the palpebral fissure", "Abnormal sharpey fiber morphology", "Abnormal shoulder morphology", "Abnormal shoulder physiology", "Abnormal size of pituitary gland", "Abnormal size of the clitoris", "Abnormal size of the dental root", "Abnormal size of the palpebral fissures", "Abnormal skin morphology of the palm", "Abnormal social behavior", "Abnormal soft palate morphology", "Abnormal speech prosody", "Abnormal sperm motility", "Abnormal spermatogenesis", "Abnormal spinal meningeal morphology", "Abnormal sputum", "Abnormal st segment", "Abnormal sternal ossification", "Abnormal sternum morphology", "Abnormal stomach morphology", "Abnormal stool composition", "Abnormal subarachnoid space morphology", "Abnormal subclavian artery morphology", "Abnormal subcutaneous fat tissue distribution", "Abnormal substantia nigra morphology", "Abnormal superior cerebellar peduncle morphology", "Abnormal sweat gland morphology", "Abnormal sweat homeostasis", "Abnormal synaptic transmission at the neuromuscular junction", "Abnormal systemic arterial morphology", "Abnormal systemic blood pressure", "Abnormal t cell activation", "Abnormal t cell morphology", "Abnormal t cell proliferation", "Abnormal t cell subset distribution", "Abnormal t wave", "Abnormal talus morphology", "Abnormal tarsal ossification", "Abnormal temper tantrums", "Abnormal temporal bone morphology", "Abnormal tendon morphology", "Abnormal testis morphology", "Abnormal thalamic mri signal intensity", "Abnormal thalamic size", "Abnormal thoracic spine morphology", "Abnormal thorax morphology", "Abnormal thrombocyte morphology", "Abnormal thrombosis", "Abnormal thumb morphology", "Abnormal thyroid hormone level", "Abnormal thyroid morphology", "Abnormal thyroid stimulating hormone level", "Abnormal tissue metabolite concentration", "Abnormal toenail morphology", "Abnormal tongue morphology", "Abnormal tongue physiology", "Abnormal trabecular bone morphology", "Abnormal tracheal morphology", "Abnormal tracheobronchial morphology", "Abnormal transferrin saturation", "Abnormal tricuspid valve morphology", "Abnormal tricuspid valve physiology", "Abnormal umbilicus morphology", "Abnormal upper limb bone morphology", "Abnormal upper motor neuron morphology", "Abnormal ureter morphology", "Abnormal ureter physiology", "Abnormal urinary color", "Abnormal urinary electrolyte concentration", "Abnormal urine alpha ketoglutarate concentration", "Abnormal urine carbohydrate level", "Abnormal urine carboxylic acid level", "Abnormal urine cytology", "Abnormal urine hormone level", "Abnormal urine magnesium concentration", "Abnormal urine metabolite level", "Abnormal urine ph", "Abnormal urine phosphate concentration", "Abnormal urine potassium concentration", "Abnormal urine protein level", "Abnormal urine sodium concentration", "Abnormal uterus morphology", "Abnormal uvea morphology", "Abnormal uvula morphology", "Abnormal vagina morphology", "Abnormal vascular morphology", "Abnormal vascular physiology", "Abnormal vena cava morphology", "Abnormal venous morphology", "Abnormal ventricular septum morphology", "Abnormal vertebral morphology", "Abnormal vertebral segmentation and fusion", "Abnormal vestibulo ocular reflex", "Abnormal visual electrophysiology", "Abnormal visual field test", "Abnormal visual fixation", "Abnormal vitamin b12 level", "Abnormal vitreous humor morphology", "Abnormal waist to hip ratio", "Abnormal z disc morphology", "Abnormalities of placenta or umbilical cord", "Abnormality iris morphology", "Abnormality of abdominal situs", "Abnormality of acid base homeostasis", "Abnormality of adrenal morphology", "Abnormality of adrenal physiology", "Abnormality of alkaline phosphatase level", "Abnormality of amino acid metabolism", "Abnormality of bladder morphology", "Abnormality of blood circulation", "Abnormality of blood volume homeostasis", "Abnormality of body mass index", "Abnormality of bone marrow cell morphology", "Abnormality of bone mineral density", "Abnormality of canine", "Abnormality of cardiovascular system electrophysiology", "Abnormality of carpal bone ossification", "Abnormality of cartilage of external ear", "Abnormality of central nervous system electrophysiology", "Abnormality of chorioretinal pigmentation", "Abnormality of chromosome segregation", "Abnormality of chromosome stability", "Abnormality of circulating adrenocorticotropin level", "Abnormality of circulating enzyme level", "Abnormality of circulating fibrinogen", "Abnormality of circulating glucocorticoid level", "Abnormality of circulating leptin level", "Abnormality of coagulation", "Abnormality of complement system", "Abnormality of coordination", "Abnormality of corneal size", "Abnormality of corneal stroma", "Abnormality of corneal thickness", "Abnormality of cranial sutures", "Abnormality of dental color", "Abnormality of dental eruption", "Abnormality of dental morphology", "Abnormality of dental structure", "Abnormality of dermal melanosomes", "Abnormality of digestive system morphology", "Abnormality of dna repair", "Abnormality of earlobe", "Abnormality of endocrine pancreas physiology", "Abnormality of epiphysis morphology", "Abnormality of exocrine pancreas physiology", "Abnormality of extrapyramidal motor function", "Abnormality of facial adipose tissue", "Abnormality of facial musculature", "Abnormality of facial skeleton", "Abnormality of facial soft tissue", "Abnormality of female external genitalia", "Abnormality of femur morphology", "Abnormality of fibula morphology", "Abnormality of finger", "Abnormality of fluid regulation", "Abnormality of folate metabolism", "Abnormality of fontanelles", "Abnormality of foveal pigmentation", "Abnormality of frontal sinus", "Abnormality of frontalis muscle belly", "Abnormality of fundus pigmentation", "Abnormality of globe location", "Abnormality of globe size", "Abnormality of glycolipid metabolism", "Abnormality of hair growth", "Abnormality of hair pigmentation", "Abnormality of hair texture", "Abnormality of hand joint mobility", "Abnormality of head blood vessel", "Abnormality of hepatobiliary system physiology", "Abnormality of hindbrain morphology", "Abnormality of humoral immunity", "Abnormality of immune serum protein physiology", "Abnormality of iron homeostasis", "Abnormality of krebs cycle metabolism", "Abnormality of lens shape", "Abnormality of limb epiphysis morphology", "Abnormality of lipoprotein cholesterol concentration", "Abnormality of long bone morphology", "Abnormality of lower limb epiphysis morphology", "Abnormality of lower limb joint", "Abnormality of lower limb metaphyses", "Abnormality of lower lip", "Abnormality of lysosomal metabolism", "Abnormality of macular pigmentation", "Abnormality of malar bones", "Abnormality of male internal genitalia", "Abnormality of masticatory muscle", "Abnormality of metacarpal epiphyses", "Abnormality of metacarpophalangeal joint", "Abnormality of mouth shape", "Abnormality of mouth size", "Abnormality of muscle size", "Abnormality of nail color", "Abnormality of neuronal migration", "Abnormality of neutrophil morphology", "Abnormality of neutrophil physiology", "Abnormality of neutrophils", "Abnormality of ocular smooth pursuit", "Abnormality of pain sensation", "Abnormality of pancreas physiology", "Abnormality of pelvic girdle bone morphology", "Abnormality of periauricular region", "Abnormality of peripheral nerves", "Abnormality of prenatal development or birth", "Abnormality of primary teeth", "Abnormality of prothrombin", "Abnormality of pulmonary circulation", "Abnormality of refraction", "Abnormality of renal excretion", "Abnormality of renin angiotensin system", "Abnormality of reproductive system physiology", "Abnormality of retinal pigmentation", "Abnormality of salivation", "Abnormality of secondary sexual hair", "Abnormality of skeletal maturation", "Abnormality of skeletal muscle fiber size", "Abnormality of skin adnexa physiology", "Abnormality of skin physiology", "Abnormality of skin pigmentation", "Abnormality of skull ossification", "Abnormality of small intestinal villus morphology", "Abnormality of somatosensory evoked potentials", "Abnormality of subcutaneous fat tissue", "Abnormality of t cell physiology", "Abnormality of taste sensation", "Abnormality of temperature regulation", "Abnormality of thalamus morphology", "Abnormality of the 1st metacarpal", "Abnormality of the 2nd toe", "Abnormality of the 3rd toe", "Abnormality of the 4th metacarpal", "Abnormality of the 5th metacarpal", "Abnormality of the 5th toe", "Abnormality of the abdominal organs", "Abnormality of the abdominal wall", "Abnormality of the achilles tendon", "Abnormality of the adrenal glands", "Abnormality of the alveolar ridges", "Abnormality of the amniotic fluid", "Abnormality of the ankles", "Abnormality of the anterior fontanelle", "Abnormality of the antihelix", "Abnormality of the antitragus", "Abnormality of the anus", "Abnormality of the auditory canal", "Abnormality of the autonomic nervous system", "Abnormality of the axillary hair", "Abnormality of the basal ganglia", "Abnormality of the biliary system", "Abnormality of the bladder", "Abnormality of the brainstem white matter", "Abnormality of the breast", "Abnormality of the calcaneus", "Abnormality of the calf", "Abnormality of the calf musculature", "Abnormality of the calvaria", "Abnormality of the carpal bones", "Abnormality of the cerebral subcortex", "Abnormality of the cerebrospinal fluid", "Abnormality of the cervical spine", "Abnormality of the cheek", "Abnormality of the chin", "Abnormality of the choanae", "Abnormality of the clitoris", "Abnormality of the coagulation cascade", "Abnormality of the columella", "Abnormality of the common coagulation pathway", "Abnormality of the costochondral junction", "Abnormality of the crus of the helix", "Abnormality of the curvature of the cornea", "Abnormality of the curvature of the vertebral column", "Abnormality of the dentition", "Abnormality of the diaphragm", "Abnormality of the diencephalon", "Abnormality of the distal phalanges of the toes", "Abnormality of the distal phalanx of the hallux", "Abnormality of the distal phalanx of the thumb", "Abnormality of the dorsal column of the spinal cord", "Abnormality of the elbow", "Abnormality of the endometrium", "Abnormality of the epididymis", "Abnormality of the epiphyses of the distal phalanx of finger", "Abnormality of the eustachian tube", "Abnormality of the external nose", "Abnormality of the extraocular muscles", "Abnormality of the extrinsic pathway", "Abnormality of the female genitalia", "Abnormality of the fetal cardiovascular system", "Abnormality of the fifth metatarsal bone", "Abnormality of the first metatarsal bone", "Abnormality of the fontanelles or cranial sutures", "Abnormality of the foot musculature", "Abnormality of the forearm", "Abnormality of the forehead", "Abnormality of the frontal hairline", "Abnormality of the gallbladder", "Abnormality of the gastric mucosa", "Abnormality of the gingiva", "Abnormality of the glabella", "Abnormality of the glenoid fossa", "Abnormality of the hairline", "Abnormality of the hallux", "Abnormality of the helix", "Abnormality of the hepatic vasculature", "Abnormality of the humeroradial joint", "Abnormality of the humerus", "Abnormality of the hypothalamus pituitary axis", "Abnormality of the hypothenar eminence", "Abnormality of the incisor", "Abnormality of the inner ear", "Abnormality of the internal auditory canal", "Abnormality of the intervertebral disk", "Abnormality of the intrahepatic bile duct", "Abnormality of the intrinsic pathway", "Abnormality of the ischium", "Abnormality of the kidney", "Abnormality of the knee", "Abnormality of the larynx", "Abnormality of the lens", "Abnormality of the leydig cells", "Abnormality of the liver", "Abnormality of the lower urinary tract", "Abnormality of the lymph nodes", "Abnormality of the lymphatic system", "Abnormality of the mastoid", "Abnormality of the maxilla", "Abnormality of the menstrual cycle", "Abnormality of the metacarpal bones", "Abnormality of the metaphysis", "Abnormality of the metopic suture", "Abnormality of the middle ear", "Abnormality of the middle ear ossicles", "Abnormality of the middle phalanges of the toes", "Abnormality of the middle phalanx of the 2nd finger", "Abnormality of the middle phalanx of the 5th finger", "Abnormality of the midface", "Abnormality of the mitochondrion", "Abnormality of the musculature of the hand", "Abnormality of the musculature of the limbs", "Abnormality of the musculature of the lower limbs", "Abnormality of the musculature of the thigh", "Abnormality of the musculature of the upper arm", "Abnormality of the musculature of the upper limbs", "Abnormality of the nail", "Abnormality of the nasal alae", "Abnormality of the nasal bone", "Abnormality of the nasal cavity", "Abnormality of the nasal dorsum", "Abnormality of the nasal septum", "Abnormality of the nasal skeleton", "Abnormality of the nasal tip", "Abnormality of the nasolabial region", "Abnormality of the neck", "Abnormality of the odontoid process", "Abnormality of the optic nerve", "Abnormality of the outer ear", "Abnormality of the ovary", "Abnormality of the palm", "Abnormality of the palpebral fissures", "Abnormality of the pancreas", "Abnormality of the parathyroid gland", "Abnormality of the parathyroid morphology", "Abnormality of the periorbital region", "Abnormality of the peripheral nervous system", "Abnormality of the peritoneum", "Abnormality of the periungual region", "Abnormality of the phalanges of the 2nd finger", "Abnormality of the phalanges of the hallux", "Abnormality of the phalanges of the toes", "Abnormality of the pharynx", "Abnormality of the philtrum", "Abnormality of the pineal gland", "Abnormality of the pinna", "Abnormality of the pituitary gland", "Abnormality of the plantar skin of foot", "Abnormality of the posterior pituitary", "Abnormality of the protein c anticoagulant pathway", "Abnormality of the proximal phalanx of the thumb", "Abnormality of the pubic bone", "Abnormality of the pubic hair", "Abnormality of the pulmonary artery", "Abnormality of the pulmonary vasculature", "Abnormality of the pulmonary veins", "Abnormality of the pylorus", "Abnormality of the radial head", "Abnormality of the radioulnar joints", "Abnormality of the ribs", "Abnormality of the scrotum", "Abnormality of the sense of smell", "Abnormality of the septum pellucidum", "Abnormality of the shoulder girdle musculature", "Abnormality of the skull base", "Abnormality of the small intestine", "Abnormality of the spinal cord", "Abnormality of the spinocerebellar tracts", "Abnormality of the spleen", "Abnormality of the stapes", "Abnormality of the subungual region", "Abnormality of the supraorbital ridges", "Abnormality of the synovia", "Abnormality of the tarsal bones", "Abnormality of the temporomandibular joint", "Abnormality of the testis size", "Abnormality of the thenar eminence", "Abnormality of the thoracic cavity", "Abnormality of the thymus", "Abnormality of the thyroid gland", "Abnormality of the tongue", "Abnormality of the tongue muscle", "Abnormality of the tonsils", "Abnormality of the tragus", "Abnormality of the ulna", "Abnormality of the umbilical cord", "Abnormality of the upper arm", "Abnormality of the upper respiratory tract", "Abnormality of the ureter", "Abnormality of the urethra", "Abnormality of the urinary system physiology", "Abnormality of the uterus", "Abnormality of the vasculature of the eye", "Abnormality of the vertebral endplates", "Abnormality of the vestibulocochlear nerve", "Abnormality of the voice", "Abnormality of the wrist", "Abnormality of the zygomatic bone", "Abnormality of thyroid physiology", "Abnormality of tibia morphology", "Abnormality of toe", "Abnormality of ulnar metaphysis", "Abnormality of upper limb epiphysis morphology", "Abnormality of upper limb joint", "Abnormality of upper limb metaphysis", "Abnormality of upper lip", "Abnormality of upper lip vermillion", "Abnormality of urinary uric acid concentration", "Abnormality of urine calcium concentration", "Abnormality of urine catecholamine concentration", "Abnormality of urine homeostasis", "Abnormality of visual evoked potentials", "Abnormality of vitamin a metabolism", "Abnormality of vitamin b metabolism", "Abnormality of vitamin b12 metabolism", "Abnormality of vitamin d metabolism", "Abnormality of vitamin e metabolism", "Abnormality of vitamin k metabolism", "Abnormality of vitamin metabolism", "Abnormality on pulmonary function testing", "Abnormally folded helix", "Abnormally large globe", "Abnormally lax or hyperextensible skin", "Abnormally low pitched voice", "Abnormally ossified vertebrae", "Abnormally shaped carpal bones", "Abscess", "Absence of pubertal development", "Absence of secondary sex characteristics", "Absence of subcutaneous fat", "Absent axillary hair", "Absent brainstem auditory responses", "Absent distal interphalangeal creases", "Absent distal phalanges", "Absent earlobe", "Absent epiphyses", "Absent eyebrow", "Absent facial hair", "Absent fingernail", "Absent forearm bone", "Absent foveal reflex", "Absent frontal sinuses", "Absent hair", "Absent hand", "Absent hypoplastic paranasal sinuses", "Absent nares", "Absent nipple", "Absent or minimally ossified vertebral bodies", "Absent outer dynein arms", "Absent palmar crease", "Absent phalangeal crease", "Absent septum pellucidum", "Absent shortened dynein arms", "Absent speech", "Absent sternal ossification", "Absent testis", "Absent thumb", "Absent thumbnail", "Absent tibia", "Absent toe", "Absent toenail", "Acanthocytosis", "Acantholysis", "Acanthosis nigricans", "Accelerated atherosclerosis", "Accelerated skeletal maturation", "Accessory oral frenulum", "Accessory spleen", "Acetabular dysplasia", "Acetabular spurs", "Achilles tendon contracture", "Achromatopsia", "Acidemia", "Acne", "Acne inversa", "Acquired abnormal hair pattern", "Acral blistering", "Acral ulceration", "Acromesomelia", "Acromicria", "Acroparesthesia", "Action tremor", "Acute coronary syndrome", "Acute encephalopathy", "Acute hepatic failure", "Acute kidney injury", "Acute leukemia", "Acute lymphoblastic leukemia", "Acute myeloid leukemia", "Acute pancreatitis", "Acute phase response", "Addictive behavior", "Adducted thumb", "Adenocarcinoma of the colon", "Adenocarcinoma of the intestines", "Adenocarcinoma of the small intestine", "Adenoma sebaceum", "Adenomatous colonic polyposis", "Adipose tissue loss", "Adrenal hyperplasia", "Adrenal hypoplasia", "Adrenal insufficiency", "Adrenal overactivity", "Adrenocortical abnormality", "Adrenocortical adenoma", "Adrenocortical carcinoma", "Adrenocorticotropic hormone deficiency", "Adrenocorticotropic hormone excess", "Adrenocorticotropin deficient adrenal insufficiency", "Adult onset", "Advanced eruption of teeth", "Advanced ossification of carpal bones", "Agammaglobulinemia", "Aganglionic megacolon", "Agenesis of central incisor", "Agenesis of cerebellar vermis", "Agenesis of corpus callosum", "Agenesis of incisor", "Agenesis of lateral incisor", "Agenesis of maxillary incisor", "Agenesis of permanent teeth", "Aggressive behavior", "Agitation", "Agnosia", "Agyria", "Airway obstruction", "Akinesia", "Alacrima", "Albinism", "Albuminuria", "Alexia", "Alkalosis", "Allergic rhinitis", "Allergy", "Alopecia", "Alopecia of scalp", "Alopecia totalis", "Alopecia universalis", "Alternating esotropia", "Alveolar cell carcinoma", "Alveolar rhabdomyosarcoma", "Alveolar ridge overgrowth", "Alzheimer disease", "Amaurosis fugax", "Ambiguous genitalia", "Ambiguous genitalia female", "Ambiguous genitalia male", "Amblyopia", "Amegakaryocytic thrombocytopenia", "Amelogenesis imperfecta", "Amenorrhea", "Aminoaciduria", "Amniotic constriction ring", "Amyloidosis", "Amyotrophic lateral sclerosis", "Anal atresia", "Anal fissure", "Anal stenosis", "Anaphylactic shock", "Anarthria", "Anasarca", "Anemia of inadequate production", "Anemic pallor", "Anencephaly", "Angina pectoris", "Angioedema", "Angiofibromas", "Angioid streaks of the fundus", "Angiokeratoma", "Angular cheilitis", "Anhidrosis", "Aniridia", "Anisocoria", "Anisocytosis", "Anisopoikilocytosis", "Anisospondyly", "Ankle clonus", "Ankle flexion contracture", "Ankle weakness", "Ankyloblepharon", "Ankyloglossia", "Ankylosis", "Annular pancreas", "Anodontia", "Anomalous trichromacy", "Anomic aphasia", "Anonychia", "Anophthalmia", "Anorectal anomaly", "Anorexia", "Anosmia", "Anotia", "Antenatal onset", "Anterior open bite malocclusion", "Anterior pituitary dysgenesis", "Anterior plagiocephaly", "Anterior rib cupping", "Anterior uveitis", "Anteriorly placed anus", "Anteverted ears", "Anti thyroid peroxidase antibody positivity", "Antineutrophil antibody positivity", "Antinuclear antibody positivity", "Antiphospholipid antibody positivity", "Aortic aneurysm", "Aortic arch aneurysm", "Aortic atherosclerotic lesion", "Aortic dissection", "Aortic regurgitation", "Aortic root aneurysm", "Aortic valve calcification", "Aortic valve stenosis", "Aphasia", "Aphthous ulcer", "Aplasia cutis congenita", "Aplasia cutis congenita of scalp", "Aplasia cutis congenita on trunk or limbs", "Aplasia cutis congenita over the scalp vertex", "Aplasia hypoplasia affecting bones of the axial skeleton", "Aplasia hypoplasia affecting the anterior segment of the eye", "Aplasia hypoplasia affecting the eye", "Aplasia hypoplasia affecting the fundus", "Aplasia hypoplasia involving bones of the feet", "Aplasia hypoplasia involving bones of the lower limbs", "Aplasia hypoplasia involving bones of the thorax", "Aplasia hypoplasia involving bones of the upper limbs", "Aplasia hypoplasia involving forearm bones", "Aplasia hypoplasia involving the carpal bones", "Aplasia hypoplasia involving the femoral head and neck", "Aplasia hypoplasia involving the metacarpal bones", "Aplasia hypoplasia involving the musculature of the upper limbs", "Aplasia hypoplasia involving the nose", "Aplasia hypoplasia involving the pelvis", "Aplasia hypoplasia involving the sinuses", "Aplasia hypoplasia involving the skeletal musculature", "Aplasia hypoplasia involving the skeleton", "Aplasia hypoplasia involving the vertebral column", "Aplasia hypoplasia of fingers", "Aplasia hypoplasia of metatarsal bones", "Aplasia hypoplasia of the 2nd finger", "Aplasia hypoplasia of the 4th metacarpal", "Aplasia hypoplasia of the 5th finger", "Aplasia hypoplasia of the 5th metacarpal", "Aplasia hypoplasia of the abdominal wall musculature", "Aplasia hypoplasia of the bladder", "Aplasia hypoplasia of the breasts", "Aplasia hypoplasia of the capital femoral epiphysis", "Aplasia hypoplasia of the cerebellar vermis", "Aplasia hypoplasia of the cerebellum", "Aplasia hypoplasia of the cerebral white matter", "Aplasia hypoplasia of the clavicles", "Aplasia hypoplasia of the colon", "Aplasia hypoplasia of the distal phalanges of the hand", "Aplasia hypoplasia of the distal phalanges of the toes", "Aplasia hypoplasia of the distal phalanx of the thumb", "Aplasia hypoplasia of the ear", "Aplasia hypoplasia of the earlobes", "Aplasia hypoplasia of the epiglottis", "Aplasia hypoplasia of the extremities", "Aplasia hypoplasia of the eyebrow", "Aplasia hypoplasia of the eyelid", "Aplasia hypoplasia of the femur", "Aplasia hypoplasia of the fibula", "Aplasia hypoplasia of the gallbladder", "Aplasia hypoplasia of the hallux", "Aplasia hypoplasia of the humerus", "Aplasia hypoplasia of the lungs", "Aplasia hypoplasia of the middle phalanges of the toes", "Aplasia hypoplasia of the nails", "Aplasia hypoplasia of the nasal bone", "Aplasia hypoplasia of the nasal septum", "Aplasia hypoplasia of the nipples", "Aplasia hypoplasia of the optic nerve", "Aplasia hypoplasia of the ovary", "Aplasia hypoplasia of the palmar creases", "Aplasia hypoplasia of the patella", "Aplasia hypoplasia of the phalanges of the 2nd finger", "Aplasia hypoplasia of the phalanges of the hallux", "Aplasia hypoplasia of the phalanges of the hand", "Aplasia hypoplasia of the phalanges of the thumb", "Aplasia hypoplasia of the phalanges of the toes", "Aplasia hypoplasia of the proximal phalanges of the hand", "Aplasia hypoplasia of the pubic bone", "Aplasia hypoplasia of the radius", "Aplasia hypoplasia of the retina", "Aplasia hypoplasia of the ribs", "Aplasia hypoplasia of the sacrum", "Aplasia hypoplasia of the scapulae", "Aplasia hypoplasia of the skin", "Aplasia hypoplasia of the spleen", "Aplasia hypoplasia of the sternum", "Aplasia hypoplasia of the thumb", "Aplasia hypoplasia of the thymus", "Aplasia hypoplasia of the thyroid gland", "Aplasia hypoplasia of the tibia", "Aplasia hypoplasia of the tongue", "Aplasia hypoplasia of the tragus", "Aplasia hypoplasia of the ulna", "Aplasia hypoplasia of the uterus", "Aplasia hypoplasia of the uvula", "Aplasia hypoplasia of the vagina", "Aplasia hypoplasia of toe", "Aplasia involving bones of the extremities", "Aplasia involving bones of the lower limbs", "Aplasia of metacarpal bones", "Aplasia of the fingers", "Aplasia of the middle phalanx of the hand", "Aplasia of the phalanges of the hand", "Aplasia of the phalanges of the toes", "Aplasia of the proximal phalanges of the hand", "Aplasia of the semicircular canal", "Aplasia of the uterus", "Aplastic anemia", "Aplastic clavicle", "Aplastic hypoplastic lacrimal glands", "Aplastic hypoplastic toenail", "Apnea", "Apneic episodes in infancy", "Apneic episodes precipitated by illness fatigue stress", "Appendicular hypotonia", "Apraxia", "Aqueductal stenosis", "Arachnodactyly", "Arachnoid hemangiomatosis", "Areflexia", "Areflexia of lower limbs", "Arm dystonia", "Arnold chiari malformation", "Arnold chiari type i malformation", "Arrhinencephaly", "Arteria lusoria", "Arterial dissection", "Arterial rupture", "Arterial stenosis", "Arterial thrombosis", "Arteriosclerosis", "Arteriovenous malformation", "Arthralgia", "Arthritis", "Arthrogryposis multiplex congenita", "Arthropathy", "Ascending aortic dissection", "Ascending tubular aorta aneurysm", "Ascites", "Aspiration", "Aspiration pneumonia", "Asterixis", "Asthenia", "Asthma", "Astigmatism", "Astrocytoma", "Astrocytosis", "Asymmetric growth", "Asymmetric septal hypertrophy", "Asymmetry of the ears", "Asymmetry of the thorax", "Atelectasis", "Athetosis", "Atlantoaxial abnormality", "Atlantoaxial dislocation", "Atlantoaxial instability", "Atonic seizure", "Atopic dermatitis", "Atresia of the external auditory canal", "Atrial arrhythmia", "Atrial flutter", "Atrioventricular canal defect", "Atrophic scars", "Atrophy degeneration affecting the brainstem", "Atrophy degeneration affecting the central nervous system", "Atrophy degeneration affecting the cerebrum", "Atrophy degeneration involving the caudate nucleus", "Atrophy degeneration involving the corticospinal tracts", "Atrophy degeneration involving the spinal cord", "Atrophy of alveolar ridges", "Attention deficit hyperactivity disorder", "Attenuation of retinal blood vessels", "Atypical absence seizure", "Auditory hallucinations", "Autism", "Autistic behavior", "Autoamputation", "Autoamputation of digits", "Autoimmune antibody positivity", "Autoimmune hemolytic anemia", "Autoimmune thrombocytopenia", "Autoimmunity", "Autophagic vacuoles", "Autosomal dominant germline de novo mutation", "Avascular necrosis", "Avascular necrosis of the capital femoral epiphysis", "Axial dystonia", "Axial muscle weakness", "Axillary pterygium", "Axonal degeneration", "Axonal degeneration regeneration", "Axonal loss", "Axonal regeneration", "Azoospermia", "B cell lymphoma", "B lymphocytopenia", "Babinski sign", "Back pain", "Bacterial endocarditis", "Barrel shaped chest", "Barrett esophagus", "Basal cell carcinoma", "Basal ganglia calcification", "Basal ganglia cysts", "Basal ganglia gliosis", "Beaded ribs", "Beaking of vertebral bodies", "Bell shaped thorax", "Benign neoplasm of the central nervous system", "Bicarbonate wasting renal tubular acidosis", "Bicarbonaturia", "Biconcave vertebral bodies", "Bicornuate uterus", "Bicoronal synostosis", "Bifid epiglottis", "Bifid nasal tip", "Bifid ribs", "Bifid scrotum", "Bifid tongue", "Bifid uterus", "Bifid uvula", "Bilateral camptodactyly", "Bilateral cleft lip", "Bilateral cleft lip and palate", "Bilateral cleft palate", "Bilateral coxa valga", "Bilateral cryptorchidism", "Bilateral external ear deformity", "Bilateral microphthalmos", "Bilateral polymicrogyria", "Bilateral ptosis", "Bilateral sensorineural hearing impairment", "Bilateral single transverse palmar creases", "Bilateral talipes equinovarus", "Bilateral tonic clonic seizure", "Bilateral tonic clonic seizure with focal onset", "Bilateral tonic clonic seizure with generalized onset", "Bile duct proliferation", "Biliary atresia", "Biliary cirrhosis", "Biliary tract abnormality", "Biliary tract neoplasm", "Bimanual synkinesia", "Biparietal narrowing", "Bird like facies", "Birth length greater than 97th percentile", "Birth length less than 3rd percentile", "Biventricular hypertrophy", "Bladder diverticulum", "Bladder neoplasm", "Bleeding with minor or no trauma", "Blepharitis", "Blepharophimosis", "Blind vagina", "Blindness", "Blistering by anatomical location", "Blistering by histological location", "Bloodstream infectious agent", "Bloody diarrhea", "Blue irides", "Blue nevus", "Blue sclerae", "Blurred vision", "Bone cyst", "Bone fracture", "Bone marrow foam cells", "Bone marrow hypercellularity", "Bone marrow hypocellularity", "Bone pain", "Bone spicule pigmentation of the retina", "Bowel diverticulosis", "Bowing of the arm", "Bowing of the legs", "Brachycephaly", "Brachydactyly", "Brachyturricephaly", "Bradycardia", "Bradykinesia", "Brain imaging abnormality", "Brain neoplasm", "Brain stem compression", "Branchial anomaly", "Branchial cyst", "Branchial fistula", "Breast aplasia", "Breast carcinoma", "Breast hypoplasia", "Breathing dysregulation", "Breech presentation", "Brisk reflexes", "Brittle hair", "Broad alveolar ridges", "Broad based gait", "Broad chin", "Broad clavicles", "Broad columella", "Broad distal phalanx of finger", "Broad eyebrow", "Broad face", "Broad femoral neck", "Broad finger", "Broad foot", "Broad forehead", "Broad hallux phalanx", "Broad jaw", "Broad long bones", "Broad metacarpals", "Broad metatarsal", "Broad nail", "Broad nasal tip", "Broad neck", "Broad palm", "Broad phalanx of the toes", "Broad philtrum", "Broad ribs", "Broad thumb", "Broad toe", "Bronchiectasis", "Bronchitis", "Bronchomalacia", "Bronchospasm", "Bruising susceptibility", "Brushfield spots", "Bruxism", "Bulbar palsy", "Bulbar signs", "Bulbous nose", "Bull s eye maculopathy", "Bundle branch block", "Buphthalmos", "Burkitt lymphoma", "Butterfly vertebrae", "Cachexia", "Caesarian section", "Cafe au lait spot", "Calcific stippling", "Calcification of cartilage", "Calcification of the aorta", "Calcinosis", "Calcium nephrolithiasis", "Calcium oxalate nephrolithiasis", "Calf muscle pseudohypertrophy", "Calvarial hyperostosis", "Calvarial osteosclerosis", "Calvarial skull defect", "Camptodactyly of toe", "Capillary hemangioma", "Capillary malformation", "Capitate hamate fusion", "Carcinoid tumor", "Carcinoma", "Cardiac arrest", "Cardiac conduction abnormality", "Cardiac diverticulum", "Cardiac rhabdomyoma", "Cardiac shunt", "Cardiac valve calcification", "Cardiomegaly", "Cardiorespiratory arrest", "Cardiovascular calcification", "Carious teeth", "Carpal bone hypoplasia", "Carpal synostosis", "Cataplexy", "Caudate atrophy", "Cavernous hemangioma", "Cavum septum pellucidum", "Celiac disease", "Cellular immunodeficiency", "Cellulitis", "Central adrenal insufficiency", "Central apnea", "Central diabetes insipidus", "Central heterochromia", "Central hypothyroidism", "Central hypoventilation", "Central nervous system cyst", "Central primitive neuroectodermal tumor", "Central scotoma", "Central sleep apnea", "Central y shaped metacarpal", "Centrally nucleated skeletal muscle fibers", "Centrocecal scotoma", "Cephalohematoma", "Cerebellar atrophy", "Cerebellar cortical atrophy", "Cerebellar cyst", "Cerebellar dysplasia", "Cerebellar hemorrhage", "Cerebellar hypoplasia", "Cerebellar malformation", "Cerebellar vermis atrophy", "Cerebral amyloid angiopathy", "Cerebral calcification", "Cerebral cortical atrophy", "Cerebral dysmyelination", "Cerebral edema", "Cerebral hamartoma", "Cerebral hemorrhage", "Cerebral hypomyelination", "Cerebral hypoplasia", "Cerebral inclusion bodies", "Cerebral palsy", "Cerebral venous thrombosis", "Cerebral visual impairment", "Cerebral white matter atrophy", "Cerebral white matter hypoplasia", "Cervical kyphosis", "Cervical myelopathy", "Cervical ribs", "Cervical spinal canal stenosis", "Cervical spine instability", "Cervical subluxation", "Cessation of head growth", "Cheilitis", "Cherry red spot of the macula", "Chest pain", "Chilblains", "Childhood onset", "Childhood onset sensorineural hearing impairment", "Childhood onset truncal obesity", "Chills", "Choanal stenosis", "Choking episodes", "Cholangiocarcinoma", "Cholangitis", "Cholecystitis", "Cholestasis", "Cholestatic liver disease", "Chondrocalcinosis", "Chondrosarcoma", "Chordee", "Chorea", "Choreoathetosis", "Choriocarcinoma", "Chorioretinal atrophy", "Chorioretinal coloboma", "Chorioretinal degeneration", "Chorioretinal dysplasia", "Chorioretinal dystrophy", "Chorioretinal hypopigmentation", "Choroid plexus carcinoma", "Choroid plexus cyst", "Choroidal melanoma", "Choroidal neovascularization", "Chromosomal breakage induced by crosslinking agents", "Chromosomal breakage induced by ionizing radiation", "Chromosome breakage", "Chronic atrophic gastritis", "Chronic axonal neuropathy", "Chronic bronchitis", "Chronic constipation", "Chronic diarrhea", "Chronic fatigue", "Chronic hemolytic anemia", "Chronic hepatic failure", "Chronic infection", "Chronic kidney disease", "Chronic leukemia", "Chronic lung disease", "Chronic lymphatic leukemia", "Chronic mucocutaneous candidiasis", "Chronic neutropenia", "Chronic noninfectious lymphadenopathy", "Chronic oral candidiasis", "Chronic otitis media", "Chronic pulmonary obstruction", "Chronic rhinitis", "Chronic sinusitis", "Chylothorax", "Cigarette paper scars", "Cirrhosis", "Cleft hard palate", "Cleft lip", "Cleft soft palate", "Cleft upper lip", "Clinodactyly", "Clinodactyly of the 2nd finger", "Clitoral hypoplasia", "Clonic seizure", "Clonus", "Cloverleaf skull", "Clubbing", "Clubbing of fingers", "Clubbing of toes", "Clumsiness", "Cns demyelination", "Cns hypomyelination", "Coarctation of aorta", "Coarse facial features", "Coarse hair", "Cochlear malformation", "Cognitive impairment", "Cogwheel rigidity", "Cold induced muscle cramps", "Colitis", "Collectionism", "Coloboma", "Colon cancer", "Color vision defect", "Color vision test abnormality", "Colorectal polyposis", "Colpocephaly", "Coma", "Combined immunodeficiency", "Communicating hydrocephalus", "Compensatory head posture", "Complete atrioventricular canal defect", "Complete duplication of phalanx of hand", "Complex febrile seizure", "Concave nail", "Concave nasal ridge", "Concentric hypertrophic cardiomyopathy", "Cone cone rod dystrophy", "Cone shaped epiphyses of the phalanges of the hand", "Cone shaped epiphysis", "Confetti like hypopigmented macules", "Confusion", "Congenital adrenal hyperplasia", "Congenital bilateral hip dislocation", "Congenital blindness", "Congenital contracture", "Congenital craniofacial dysostosis", "Congenital diaphragmatic hernia", "Congenital finger flexion contractures", "Congenital hemolytic anemia", "Congenital hepatic fibrosis", "Congenital hip dislocation", "Congenital hypothyroidism", "Congenital ichthyosiform erythroderma", "Congenital localized absence of skin", "Congenital malformation of the great arteries", "Congenital malformation of the left heart", "Congenital malformation of the right heart", "Congenital muscular dystrophy", "Congenital muscular torticollis", "Congenital nonbullous ichthyosiform erythroderma", "Congenital nystagmus", "Congenital onset", "Congenital posterior urethral valve", "Congenital sensorineural hearing impairment", "Congenital stationary night blindness", "Congenital thrombocytopenia", "Congestive heart failure", "Conical incisor", "Conical tooth", "Conjugated hyperbilirubinemia", "Conjunctival hamartoma", "Connective tissue nevi", "Conspicuously happy disposition", "Constipation", "Constitutional symptom", "Constriction of peripheral visual field", "Contiguous gene syndrome", "Contractures involving the joints of the feet", "Contractures of the joints of the lower limbs", "Contractures of the joints of the upper limbs", "Contractures of the large joints", "Convex nasal ridge", "Coombs positive hemolytic anemia", "Cor pulmonale", "Corneal dystrophy", "Corneal erosion", "Corneal neovascularization", "Corneal opacity", "Corneal scarring", "Corneal ulceration", "Coronal cleft vertebrae", "Coronal craniosynostosis", "Coronary artery aneurysm", "Coronary artery atherosclerosis", "Corpus callosum atrophy", "Cortical cataract", "Cortical dysplasia", "Cortical myoclonus", "Cortical thickening of long bone diaphyses", "Corticospinal tract hypoplasia", "Cough", "Coxa valga", "Coxa vara", "Crackles", "Cranial asymmetry", "Cranial hyperostosis", "Cranial nerve compression", "Craniofacial asymmetry", "Craniofacial dysostosis", "Craniofacial hyperostosis", "Craniofacial osteosclerosis", "Craniosynostosis", "Crossed fused renal ectopia", "Crumpled long bones", "Cryptorchidism", "Csf lymphocytic pleiocytosis", "Csf pleocytosis", "Cubitus valgus", "Cupped ear", "Cupped ribs", "Curly eyelashes", "Curly hair", "Cutaneous abscess", "Cutaneous amyloidosis", "Cutaneous cyst", "Cutaneous finger syndactyly", "Cutaneous melanoma", "Cutaneous photosensitivity", "Cutaneous syndactyly", "Cutaneous syndactyly of toes", "Cutis laxa", "Cutis marmorata", "Cyanosis", "Cyanotic episode", "Cyclopia", "Cystathioninemia", "Cystic hygroma", "Cystic liver disease", "Cystic renal dysplasia", "Cystinuria", "Cystoid macular edema", "Cytochrome c oxidase negative muscle fibers", "Dacryocystitis", "Dark urine", "Death in adolescence", "Death in adulthood", "Death in childhood", "Death in infancy", "Decerebrate rigidity", "Decreased absent ankle reflexes", "Decreased achilles reflex", "Decreased activity of mitochondrial complex i", "Decreased activity of mitochondrial complex ii", "Decreased activity of mitochondrial complex iii", "Decreased activity of mitochondrial complex iv", "Decreased activity of nadph oxidase", "Decreased activity of the pyruvate dehydrogenase complex", "Decreased adenosylcobalamin", "Decreased adipose tissue", "Decreased calvarial ossification", "Decreased cd4 cd8 ratio", "Decreased cervical spine flexion due to contractures of posterior cervical muscles", "Decreased cervical spine mobility", "Decreased circulating acth level", "Decreased circulating aldosterone level", "Decreased circulating androgen concentration", "Decreased circulating antibody level", "Decreased circulating copper concentration", "Decreased circulating cortisol level", "Decreased circulating follicle stimulating hormone concentration", "Decreased circulating gaba concentration", "Decreased circulating gonadotropin concentration", "Decreased circulating iga level", "Decreased circulating igg level", "Decreased circulating igg subclass level", "Decreased circulating level of specific antibody", "Decreased circulating progesterone", "Decreased circulating total iga", "Decreased circulating total igg", "Decreased circulating total igm", "Decreased corneal reflex", "Decreased csf homovanillic acid", "Decreased facial expression", "Decreased fertility", "Decreased fertility in females", "Decreased fertility in males", "Decreased head circumference", "Decreased lacrimation", "Decreased ldl cholesterol concentration", "Decreased libido", "Decreased light and dark adapted electroretinogram amplitude", "Decreased lymphocyte apoptosis", "Decreased lymphocyte proliferation in response to mitogen", "Decreased mean corpuscular volume", "Decreased methylcobalamin", "Decreased methylmalonyl coa mutase activity", "Decreased muscle mass", "Decreased number of large peripheral myelinated nerve fibers", "Decreased number of peripheral myelinated nerve fibers", "Decreased palmar creases", "Decreased patellar reflex", "Decreased plasma carnitine", "Decreased proportion of cd3 positive t cells", "Decreased proportion of cd4 positive helper t cells", "Decreased proportion of cd8 positive t cells", "Decreased pulmonary function", "Decreased serum complement c3", "Decreased serum complement c4", "Decreased serum insulin like growth factor 1", "Decreased serum iron", "Decreased size of nerve terminals", "Decreased specific anti polysaccharide antibody level", "Decreased specific antibody response to protein vaccine", "Decreased specific antibody response to vaccination", "Decreased specific pneumococcal antibody level", "Decreased testicular size", "Decreased urine output", "Decreased vigilance", "Deep palmar crease", "Deep philtrum", "Deep plantar creases", "Deep set nails", "Deep venous thrombosis", "Deeply set eye", "Defective dna repair after ultraviolet radiation damage", "Defective t cell proliferation", "Deformed rib cage", "Deformed sella turcica", "Deformed tarsal bones", "Degeneration of the lateral corticospinal tracts", "Degeneration of the striatum", "Dehydration", "Delayed ability to roll over", "Delayed ability to sit", "Delayed ability to stand", "Delayed ability to walk", "Delayed closure of the anterior fontanelle", "Delayed cns myelination", "Delayed cranial suture closure", "Delayed epiphyseal ossification", "Delayed eruption of permanent teeth", "Delayed eruption of primary teeth", "Delayed eruption of teeth", "Delayed fine motor development", "Delayed gross motor development", "Delayed menarche", "Delayed myelination", "Delayed ossification of carpal bones", "Delayed puberty", "Delayed social development", "Delirium", "Delusions", "Dementia", "Demyelinating peripheral neuropathy", "Dental crowding", "Dental malocclusion", "Depletion of mitochondrial dna in muscle tissue", "Deposits immunoreactive to beta amyloid protein", "Depressed nasal bridge", "Depressed nasal ridge", "Depressed nasal tip", "Depression", "Dermal atrophy", "Dermal translucency", "Dermatological manifestations of systemic disorders", "Descending aortic dissection", "Desquamation of skin soon after birth", "Developmental cataract", "Developmental glaucoma", "Developmental regression", "Developmental stagnation", "Deviated nasal septum", "Deviation of the 2nd finger", "Deviation of the 3rd finger", "Deviation of the hallux", "Deviation of the hand or of fingers of the hand", "Deviation of the thumb", "Deviation of toes", "Diabetes insipidus", "Dialeptic seizure", "Diaphragmatic eventration", "Diaphragmatic paralysis", "Diaphragmatic weakness", "Diaphyseal sclerosis", "Diaphyseal thickening", "Diarrhea", "Diastasis recti", "Diastema", "Dicarboxylic aciduria", "Difficulty climbing stairs", "Difficulty in tongue movements", "Difficulty running", "Difficulty standing", "Difficulty walking", "Diffuse alveolar hemorrhage", "Diffuse cerebellar atrophy", "Diffuse cerebral atrophy", "Diffuse mesangial sclerosis", "Diffuse palmoplantar hyperkeratosis", "Diffuse white matter abnormalities", "Digenic inheritance", "Dilatation of the cerebral artery", "Dilatation of the ventricular cavity", "Dilated cardiomyopathy", "Dilated fourth ventricle", "Dilated third ventricle", "Dilation of lateral ventricles", "Dilation of virchow robin spaces", "Diminished ability to concentrate", "Diminished motivation", "Diminished movement", "Dimple chin", "Diplopia", "Disinhibition", "Displacement of the urethral meatus", "Disproportionate short limb short stature", "Disproportionate short stature", "Disproportionate short trunk short stature", "Disproportionate tall stature", "Disseminated intravascular coagulation", "Distal amyotrophy", "Distal arthrogryposis", "Distal joint laxity", "Distal lower limb amyotrophy", "Distal lower limb muscle weakness", "Distal muscle weakness", "Distal peripheral sensory neuropathy", "Distal sensory impairment", "Distal sensory impairment of all modalities", "Distal sensory loss of all modalities", "Distal upper limb amyotrophy", "Distal upper limb muscle weakness", "Disturbance of facial expression", "Dolichocephaly", "Double aortic arch", "Down sloping shoulders", "Downslanted palpebral fissures", "Downturned corners of mouth", "Drowsiness", "Drusen", "Dry hair", "Dry skin", "Duodenal adenocarcinoma", "Duodenal atresia", "Duodenal stenosis", "Duodenal ulcer", "Duplicated collecting system", "Duplication involving bones of the feet", "Duplication of hand bones", "Duplication of phalanx of hallux", "Duplication of the distal phalanx of hand", "Duplication of the distal phalanx of the thumb", "Duplication of thumb phalanx", "Dysarthria", "Dyscalculia", "Dyschromatopsia", "Dysdiadochokinesis", "Dysesthesia", "Dysgammaglobulinemia", "Dysgenesis of the cerebellar vermis", "Dysgenesis of the hippocampus", "Dysgerminoma", "Dysgraphia", "Dyskinesia", "Dyslexia", "Dysmenorrhea", "Dysmetria", "Dysmetric saccades", "Dysostosis multiplex", "Dyspareunia", "Dysphagia", "Dysphasia", "Dysphonia", "Dysplasia of the femoral head", "Dysplastic corpus callosum", "Dyspnea", "Dystonia", "Dystrophic fingernails", "Dystrophic toenail", "Dysuria", "Ear pain", "Early onset absence seizures", "Early onset of sexual maturation", "Easy fatigability", "Ecchymosis", "Echolalia", "Eclabion", "Eclampsia", "Ectodermal dysplasia", "Ectopia lentis", "Ectopia pupillae", "Ectopic anus", "Ectopic calcification", "Ectopic kidney", "Ectrodactyly", "Ectropion", "Ectropion of lower eyelids", "Eczema", "Edema of the dorsum of feet", "Edema of the dorsum of hands", "Eeg with abnormally slow frequencies", "Eeg with burst suppression", "Eeg with continuous slow activity", "Eeg with focal epileptiform discharges", "Eeg with focal sharp slow waves", "Eeg with focal sharp waves", "Eeg with focal spike waves", "Eeg with focal spikes", "Eeg with frontal epileptiform discharges", "Eeg with generalized sharp slow waves", "Eeg with generalized slow activity", "Eeg with irregular generalized spike and wave complexes", "Eeg with multifocal slow activity", "Eeg with polyspike wave complexes", "Eeg with spike wave complexes", "Elbow ankylosis", "Elbow flexion contracture", "Elevated alkaline phosphatase of bone origin", "Elevated calcitonin", "Elevated circulating alanine aminotransferase concentration", "Elevated circulating aspartate aminotransferase concentration", "Elevated circulating follicle stimulating hormone level", "Elevated circulating glutaric acid concentration", "Elevated circulating growth hormone concentration", "Elevated circulating long chain fatty acid concentration", "Elevated circulating parathyroid hormone level", "Elevated circulating thyroid stimulating hormone concentration", "Elevated creatine kinase after exercise", "Elevated diastolic blood pressure", "Elevated gamma glutamyltransferase level", "Elevated hemoglobin a1c", "Elevated hepatic transaminase", "Elevated lactate pyruvate ratio", "Elevated mean arterial pressure", "Elevated proportion of cd4 negative cd8 negative alpha beta regulatory t cells", "Elevated pulmonary artery pressure", "Elevated serum acid phosphatase", "Elevated systolic blood pressure", "Elevated tissue non specific alkaline phosphatase", "Elevated total serum tryptase", "Elevated urinary carboxylic acid", "Elevated urinary delta aminolevulinic acid", "Elevated urinary dicarboxylic acid level", "Elevated urinary monocarboxylic acid level", "Elfin facies", "Elliptocytosis", "Elongated superior cerebellar peduncle", "Embryonal neoplasm", "Embryonal renal neoplasm", "Emg abnormality", "Emg axonal abnormality", "Emg chronic denervation signs", "Emg decremental response of compound muscle action potential to repetitive nerve stimulation", "Emg impaired neuromuscular transmission", "Emg myopathic abnormalities", "Emg myotonic discharges", "Emg neuropathic changes", "Emg slow motor conduction", "Emotional lability", "Emphysema", "Enamel hypoplasia", "Encephalocele", "Encephalomalacia", "Encephalopathy", "Enchondroma", "Endocardial fibroelastosis", "Endocardial fibrosis", "Endocarditis", "Enlarged cerebellum", "Enlarged cisterna magna", "Enlarged interphalangeal joints", "Enlarged joints", "Enlarged kidney", "Enlarged metaphyses", "Enlarged ovaries", "Enlarged posterior fossa", "Enlarged thorax", "Enlarged tonsils", "Enlargement of the costochondral junction", "Enlargement of the wrists", "Enterocolitis", "Enthesitis", "Entropion", "Enuresis", "Ependymoma", "Epicanthus", "Epicanthus inversus", "Epidermal acanthosis", "Epidermal hyperkeratosis", "Epidermal nevus", "Epidermoid cyst", "Epigastric pain", "Epileptic aura", "Epileptic encephalopathy", "Epileptic spasm", "Epiphora", "Epiphyseal dysplasia", "Epiphyseal stippling", "Epiretinal membrane", "Episodic ataxia", "Episodic hyperhidrosis", "Episodic hypertension", "Episodic pain", "Episodic respiratory distress", "Episodic tachypnea", "Episodic vomiting", "Epispadias", "Epistaxis", "Equinovarus deformity", "Equinus calcaneus", "Erectile dysfunction", "Erlenmeyer flask deformity of the femurs", "Eruption failure", "Erysipelas", "Erythema", "Erythema nodosum", "Erythematous papule", "Erythematous plaque", "Erythrocyte inclusion bodies", "Erythroderma", "Erythroid hyperplasia", "Erythroid hypoplasia", "Esodeviation", "Esophageal atresia", "Esophageal carcinoma", "Esophageal neoplasm", "Esophageal stenosis", "Esophageal stricture", "Esophageal varix", "Esophagitis", "Ethylmalonic aciduria", "Eunuchoid habitus", "Euryblepharon", "Eversion of lateral third of lower eyelids", "Everted upper lip vermilion", "Exaggerated cupid s bow", "Exaggerated startle response", "Exanthem", "Excessive daytime somnolence", "Excessive salivation", "Excessive wrinkled skin", "Excessive wrinkling of palmar skin", "Exercise induced muscle cramps", "Exercise induced muscle fatigue", "Exercise induced muscle stiffness", "Exercise induced myalgia", "Exercise induced myoglobinuria", "Exercise induced rhabdomyolysis", "Exercise intolerance", "Exertional dyspnea", "Exodeviation", "Exostoses", "Expressive aphasia", "Expressive language delay", "External ear malformation", "External genital hypoplasia", "External ophthalmoplegia", "Extra axial cerebrospinal fluid accumulation", "Extrahepatic cholestasis", "Extramedullary hematopoiesis", "Extrapyramidal dyskinesia", "Extrapyramidal muscular rigidity", "Eyelid coloboma", "Eyelid myoclonus", "Facial asymmetry", "Facial capillary hemangioma", "Facial cleft", "Facial diplegia", "Facial edema", "Facial erythema", "Facial grimacing", "Facial hemangioma", "Facial hyperostosis", "Facial hypertrichosis", "Facial hypotonia", "Facial myokymia", "Facial paralysis", "Facial shape deformation", "Facial telangiectasia", "Facial tics", "Failure of eruption of permanent teeth", "Failure to thrive", "Failure to thrive in infancy", "Fair hair", "Falls", "Fasciculations", "Fasting hyperinsulinemia", "Fasting hypoglycemia", "Fat malabsorption", "Fatigable weakness of bulbar muscles", "Fatigable weakness of distal limb muscles", "Fatigable weakness of respiratory muscles", "Fatigable weakness of skeletal muscles", "Fatigable weakness of swallowing muscles", "Fatiguable weakness of proximal limb muscles", "Fatigue", "Fatty replacement of skeletal muscle", "Feeding difficulties", "Feeding difficulties in infancy", "Female external genitalia in individual with 46 xy karyotype", "Female hypogonadism", "Female infertility", "Female pseudohermaphroditism", "Female reproductive system neoplasm", "Female sexual dysfunction", "Femoral bowing", "Femoral hernia", "Fetal akinesia sequence", "Fetal distress", "Fetal onset", "Fetal polyuria", "Fetal ultrasound soft marker", "Fever", "Fibroadenoma of the breast", "Fibrosarcoma", "Fibrous tissue neoplasm", "Fibular aplasia", "Fibular hypoplasia", "Fine hair", "Finger agnosia", "Finger clinodactyly", "Finger swelling", "Finger syndactyly", "Fingernail dysplasia", "Fingerprint intracellular accumulation of autofluorescent lipopigment storage material", "First degree atrioventricular block", "First dorsal interossei muscle weakness", "Flank pain", "Flared iliac wing", "Flared metaphysis", "Flared nostrils", "Flaring of rib cage", "Flat acetabular roof", "Flat cornea", "Flat face", "Flat forehead", "Flat nasal alae", "Flat occiput", "Flattened epiphysis", "Flattened femoral epiphysis", "Flattened femoral head", "Flexion contracture of digit", "Flexion contracture of thumb", "Fluctuations in consciousness", "Flushing", "Foam cells", "Focal aware seizure", "Focal clonic seizure", "Focal cortical dysplasia", "Focal cortical dysplasia type ii", "Focal dystonia", "Focal emotional seizure", "Focal hemiclonic seizure", "Focal impaired awareness seizure", "Focal motor seizure", "Focal motor status epilepticus", "Focal myoclonic seizure", "Focal non motor seizure", "Focal onset seizure", "Focal segmental glomerulosclerosis", "Focal sensory seizure", "Focal t2 hyperintense basal ganglia lesion", "Focal t2 hyperintense brainstem lesion", "Focal tonic seizure", "Focal white matter lesions", "Follicular hyperkeratosis", "Follicular hyperplasia", "Follicular thyroid carcinoma", "Food allergy", "Food intolerance", "Foot acroosteolysis", "Foot dorsiflexor weakness", "Foot oligodactyly", "Fractures of the long bones", "Fragile nails", "Fragile skin", "Fragmented epiphyses", "Freckling", "Frequent falls", "Frontal balding", "Frontal cortical atrophy", "Frontal hirsutism", "Frontal lobe dementia", "Frontotemporal cerebral atrophy", "Frontotemporal dementia", "Full cheeks", "Fulminant hepatic failure", "Functional abnormality of male internal genitalia", "Functional abnormality of the gastrointestinal tract", "Functional abnormality of the inner ear", "Functional abnormality of the middle ear", "Functional intestinal obstruction", "Functional motor deficit", "Furrowed tongue", "Fused cervical vertebrae", "Fusion of the cerebellar hemispheres", "Gait ataxia", "Gait disturbance", "Gait imbalance", "Galactorrhea", "Ganglioneuroblastoma", "Ganglioneuroma", "Gangrene", "Gastric ulcer", "Gastritis", "Gastroesophageal reflux", "Gastrointestinal atresia", "Gastrointestinal carcinoma", "Gastrointestinal hemorrhage", "Gastrointestinal infarctions", "Gastrointestinal inflammation", "Gastrointestinal obstruction", "Gastrointestinal stroma tumor", "Gastroparesis", "Gastrostomy tube feeding in infancy", "Gaze evoked horizontal nystagmus", "Gaze evoked nystagmus", "Generalized abnormality of skin", "Generalized aminoaciduria", "Generalized amyotrophy", "Generalized clonic seizure", "Generalized dystonia", "Generalized edema", "Generalized hirsutism", "Generalized hyperkeratosis", "Generalized hyperpigmentation", "Generalized hyperreflexia", "Generalized hypertrichosis", "Generalized hypopigmentation", "Generalized hypopigmentation of hair", "Generalized hypotonia", "Generalized joint laxity", "Generalized limb muscle atrophy", "Generalized lipodystrophy", "Generalized lymphadenopathy", "Generalized muscle weakness", "Generalized myoclonic atonic seizure", "Generalized myoclonic seizure", "Generalized neonatal hypotonia", "Generalized onset motor seizure", "Generalized onset seizure", "Generalized osteoporosis", "Generalized osteosclerosis", "Generalized tonic seizure", "Genetic anticipation", "Genital neoplasm", "Genu recurvatum", "Genu valgum", "Genu varum", "Germ cell neoplasia", "Germinoma", "Giant platelets", "Giant somatosensory evoked potentials", "Gingival bleeding", "Gingival fibromatosis", "Gingival overgrowth", "Gingival recession", "Gingivitis", "Glandular hypospadias", "Glaucoma", "Glioblastoma multiforme", "Glioma", "Gliosis", "Global brain atrophy", "Glomerular deposits", "Glomerular sclerosis", "Glomerulonephritis", "Glomerulopathy", "Glomus jugular tumor", "Glossitis", "Glossoptosis", "Glucagonoma", "Glucose intolerance", "Glutaric aciduria", "Glycosuria", "Goiter", "Gonadal dysgenesis", "Gonadal neoplasm", "Gonadoblastoma", "Gonosomal inheritance", "Gout", "Gowers sign", "Grammar specific speech disorder", "Granulocytopenia", "Granulomatosis", "Gray matter heterotopia", "Gynecomastia", "Hallucinations", "Hallux valgus", "Hamartoma", "Hamartoma of the eye", "Hamartoma of tongue", "Hamartomatous polyposis", "Hammertoe", "Hamstring contractures", "Hand apraxia", "Hand clenching", "Hand muscle weakness", "Hand oligodactyly", "Hand polydactyly", "Hand tremor", "Handgrip myotonia", "Happy demeanor", "Hashimoto thyroiditis", "Head banging", "Head titubation", "Head tremor", "Headache", "Heart block", "Heat intolerance", "Heinz bodies", "Hemangioblastoma", "Hemangiomatosis", "Hematemesis", "Hematochezia", "Hematological neoplasm", "Hemianopia", "Hemiatrophy", "Hemifacial spasm", "Hemihypertrophy", "Hemimegalencephaly", "Hemiparesis", "Hemiplegia hemiparesis", "Hemivertebrae", "Hemoglobinuria", "Hemolytic anemia", "Hemoptysis", "Hemorrhage of the eye", "Heparan sulfate excretion in urine", "Hepatic cysts", "Hepatic encephalopathy", "Hepatic failure", "Hepatic fibrosis", "Hepatic necrosis", "Hepatitis", "Hepatoblastoma", "Hepatocellular adenoma", "Hepatocellular carcinoma", "Hepatomegaly", "Hepatosplenomegaly", "Hereditary nonpolyposis colorectal carcinoma", "Hernia", "Herpes simplex encephalitis", "Heterochromia iridis", "Heterogeneous", "Heteronymous hemianopia", "Heterophoria", "Heterotaxy", "Heterotropia", "Hiatus hernia", "High anterior hairline", "High forehead", "High frequency hearing impairment", "High frequency sensorineural hearing impairment", "High hypermetropia", "High myopia", "High narrow palate", "High palate", "High pitched voice", "Highly arched eyebrow", "Hip contracture", "Hip dislocation", "Hip dysplasia", "Hip flexor weakness", "Hip osteoarthritis", "Hip pain", "Hip subluxation", "Hirsutism", "Hoarse cry", "Hoarse voice", "Hodgkin lymphoma", "Holoprosencephaly", "Homocystinuria", "Honeycomb lung", "Horizontal eyebrow", "Horizontal nystagmus", "Horizontal pendular nystagmus", "Horizontal ribs", "Horseshoe kidney", "Humeroradial synostosis", "Hydranencephaly", "Hydrocele testis", "Hydrocephalus", "Hydrops fetalis", "Hydroureter", "Hydroxyprolinuria", "Hyperactive deep tendon reflexes", "Hyperactive patellar reflex", "Hyperactivity", "Hyperacusis", "Hyperaldosteronism", "Hyperammonemia", "Hyperautofluorescent retinal lesion", "Hypercalcemia", "Hyperchloremic acidosis", "Hypercholesterolemia", "Hypercoagulability", "Hyperconvex fingernails", "Hyperconvex nail", "Hyperesthesia", "Hyperextensibility at wrists", "Hyperextensibility of the finger joints", "Hyperextensibility of the knee", "Hyperextensible skin", "Hypergalactosemia", "Hypergastrinemia", "Hyperglycemia", "Hypergonadotropic hypogonadism", "Hypergranulosis", "Hyperhidrosis", "Hyperhomocystinemia", "Hyperinsulinemic hypoglycemia", "Hyperintensity of cerebral white matter on mri", "Hyperkalemia", "Hyperkeratosis", "Hyperkeratotic papule", "Hyperketonemia", "Hyperkinetic movements", "Hyperlipidemia", "Hyperlipoproteinemia", "Hyperlordosis", "Hypermagnesemia", "Hypermethioninemia", "Hypermetric saccades", "Hypermetropia", "Hypernatriuria", "Hyperorality", "Hyperostosis", "Hyperoxaluria", "Hyperparathyroidism", "Hyperphenylalaninemia", "Hyperphosphatemia", "Hyperphosphaturia", "Hyperpigmentation in sun exposed areas", "Hyperpigmentation of the fundus", "Hyperpigmentation of the skin", "Hyperpituitarism", "Hyperplasia of the maxilla", "Hyperreflexia", "Hyperreflexia in upper limbs", "Hypersomnia", "Hypersplenism", "Hypertelorism", "Hypertension associated with pheochromocytoma", "Hypertensive crisis", "Hyperthyroidism", "Hypertonia", "Hypertrichosis", "Hypertriglyceridemia", "Hypertrophic cardiomyopathy", "Hypertrophic nerve changes", "Hyperuricemia", "Hyperuricosuria", "Hyperventilation", "Hypoamylasemia", "Hypocalcemia", "Hypocalcemic seizures", "Hypocalcemic tetany", "Hypocalciuria", "Hypochloremia", "Hypocholesterolemia", "Hypochromia", "Hypochromic anemia", "Hypochromic microcytic anemia", "Hypodontia", "Hypoglycemic coma", "Hypoglycemic seizures", "Hypogonadism", "Hypogonadotropic hypogonadism", "Hypohidrosis", "Hypointensity of cerebral white matter on mri", "Hypokalemia", "Hypokalemic alkalosis", "Hypokalemic metabolic alkalosis", "Hypoketotic hypoglycemia", "Hypokinesia", "Hypolipidemia", "Hypolipoproteinemia", "Hypomelanotic macule", "Hypomethioninemia", "Hypometric saccades", "Hypomimic face", "Hypoparathyroidism", "Hypophosphatemia", "Hypophosphatemic rickets", "Hypopigmentation of the fundus", "Hypopigmentation of the skin", "Hypopigmented macule", "Hypopigmented skin patches", "Hypopituitarism", "Hypoplasia of olfactory tract", "Hypoplasia of penis", "Hypoplasia of teeth", "Hypoplasia of the brainstem", "Hypoplasia of the corpus callosum", "Hypoplasia of the ear cartilage", "Hypoplasia of the epiglottis", "Hypoplasia of the femoral head", "Hypoplasia of the fovea", "Hypoplasia of the frontal lobes", "Hypoplasia of the iris", "Hypoplasia of the musculature", "Hypoplasia of the odontoid process", "Hypoplasia of the olfactory bulb", "Hypoplasia of the pons", "Hypoplasia of the radius", "Hypoplasia of the uterus", "Hypoplasia of the vagina", "Hypoplasia of the ventral pons", "Hypoplastic anemia", "Hypoplastic aortic arch", "Hypoplastic cervical vertebrae", "Hypoplastic dermoepidermal hemidesmosomes", "Hypoplastic facial bones", "Hypoplastic female external genitalia", "Hypoplastic fifth fingernail", "Hypoplastic fifth toenail", "Hypoplastic fingernail", "Hypoplastic frontal sinuses", "Hypoplastic heart", "Hypoplastic helices", "Hypoplastic hippocampus", "Hypoplastic ilia", "Hypoplastic iliac wing", "Hypoplastic ischia", "Hypoplastic labia majora", "Hypoplastic labia minora", "Hypoplastic nipples", "Hypoplastic pelvis", "Hypoplastic pubic rami", "Hypoplastic spleen", "Hypoplastic toenails", "Hypoplastic vertebral bodies", "Hypoproteinemia", "Hyporeflexia", "Hyporeflexia of lower limbs", "Hyporeflexia of upper limbs", "Hyposmia", "Hypotelorism", "Hypotension", "Hypothalamic gonadotropin releasing hormone deficiency", "Hypothalamic hamartoma", "Hypothalamic hypothyroidism", "Hypothermia", "Hypotriglyceridemia", "Hypouricemia", "Hypoventilation", "Hypovolemic shock", "Hypsarrhythmia", "Ichthyosis", "Ileus", "Imbalanced hemoglobin synthesis", "Immotile sperm", "Immune dysregulation", "Immunodeficiency", "Immunologic hypersensitivity", "Impacted tooth", "Impaired adp induced platelet aggregation", "Impaired antigen specific response", "Impaired collagen induced platelet aggregation", "Impaired distal proprioception", "Impaired distal tactile sensation", "Impaired distal vibration sensation", "Impaired epinephrine induced platelet aggregation", "Impaired glucose tolerance", "Impaired horizontal smooth pursuit", "Impaired lymphocyte transformation with phytohemagglutinin", "Impaired mastication", "Impaired neutrophil bactericidal activity", "Impaired oropharyngeal swallow response", "Impaired pain sensation", "Impaired proprioception", "Impaired smooth pursuit", "Impaired social interactions", "Impaired t cell function", "Impaired tactile sensation", "Impaired tandem gait", "Impaired temperature sensation", "Impaired use of nonverbal behaviors", "Impaired vibration sensation at ankles", "Impaired vibration sensation in the lower limbs", "Impaired vibratory sensation", "Impaired visuospatial constructive cognition", "Impairment in personality functioning", "Impairment of activities of daily living", "Impotence", "Inability to walk", "Inappropriate antidiuretic hormone secretion", "Inappropriate behavior", "Inappropriate crying", "Inappropriate laughter", "Incisor macrodontia", "Incomitant strabismus", "Incomplete partition of the cochlea type ii", "Incomplete penetrance", "Incomprehensible speech", "Incoordination", "Increased adipose tissue", "Increased arm span", "Increased aspartate family amino acid level in urine", "Increased b cell count", "Increased blood pressure", "Increased blood urea nitrogen", "Increased body mass index", "Increased body weight", "Increased bone mineral density", "Increased c peptide level", "Increased cerebral lipofuscin", "Increased circulating acth level", "Increased circulating androgen concentration", "Increased circulating antibody level", "Increased circulating cortisol level", "Increased circulating gonadotropin level", "Increased circulating iga level", "Increased circulating igg level", "Increased circulating igm level", "Increased circulating lactate dehydrogenase concentration", "Increased circulating prolactin concentration", "Increased circulating renin level", "Increased connective tissue", "Increased csf lactate", "Increased density of long bones", "Increased endomysial connective tissue", "Increased fecal porphyrin", "Increased female libido", "Increased head circumference", "Increased hepatic glycogen content", "Increased hepatocellular lipid droplets", "Increased intracranial pressure", "Increased intramyocellular lipid droplets", "Increased laxity of ankles", "Increased ldl cholesterol concentration", "Increased level of hippuric acid in urine", "Increased level of l fucose in urine", "Increased mean corpuscular hemoglobin concentration", "Increased mean corpuscular volume", "Increased megakaryocyte count", "Increased muscle fatiguability", "Increased muscle glycogen content", "Increased muscle lipid content", "Increased nuchal translucency", "Increased overbite", "Increased proportion of cd25 mast cells", "Increased proteinogenic amino acid level in urine", "Increased sensitivity to ionizing radiation", "Increased serine family amino acid in urine", "Increased serum iron", "Increased serum lactate", "Increased serum pyruvate", "Increased serum serotonin", "Increased serum testosterone level", "Increased skull ossification", "Increased sulfur amino acid level in urine", "Increased susceptibility to fractures", "Increased theta frequency activity in eeg", "Increased total bilirubin", "Increased urinary cortisol level", "Increased urinary non proteinogenic amino acid level", "Increased urinary potassium", "Increased urine alpha ketoglutarate concentration", "Increased urine proteinogenic amino acid derivative level", "Increased vertebral height", "Ineffective esophageal peristalsis", "Infantile axial hypotonia", "Infantile encephalopathy", "Infantile muscular hypotonia", "Infantile onset", "Infantile spasms", "Infection related seizure", "Infectious encephalitis", "Inferior lens subluxation", "Inferior vermis hypoplasia", "Infertility", "Inflammation of the large intestine", "Inflammatory abnormality of the eye", "Inflexible adherence to routines or rituals", "Inguinal freckling", "Inguinal hernia", "Insidious onset", "Insomnia", "Inspiratory stridor", "Insulin resistance", "Insulin resistant diabetes mellitus", "Insulinoma", "Intellectual disability borderline", "Intellectual disability mild", "Intellectual disability moderate", "Intellectual disability profound", "Intellectual disability progressive", "Intellectual disability severe", "Intercostal muscle weakness", "Interictal eeg abnormality", "Intermittent diarrhea", "Intermittent episodes of respiratory insufficiency due to muscle weakness", "Internally nucleated skeletal muscle fibers", "Interrupted aortic arch", "Interstitial cardiac fibrosis", "Intestinal atresia", "Intestinal bleeding", "Intestinal carcinoid", "Intestinal fistula", "Intestinal hypoplasia", "Intestinal malrotation", "Intestinal polyp", "Intestinal pseudo obstruction", "Intraalveolar phospholipid accumulation", "Intracellular accumulation of autofluorescent lipopigment storage material", "Intracranial hemorrhage", "Intracranial meningioma", "Intractable diarrhea", "Intrauterine growth retardation", "Intrinsic hand muscle atrophy", "Intussusception", "Inverted nipples", "Involuntary movements", "Iridocyclitis", "Iris atrophy", "Iris coloboma", "Iris hypopigmentation", "Iron accumulation in brain", "Iron accumulation in globus pallidus", "Iron deficiency anemia", "Irregular acetabular roof", "Irregular capital femoral epiphysis", "Irregular epiphyses", "Irregular femoral epiphysis", "Irregular hyperpigmentation", "Irregular iliac crest", "Irregular menstruation", "Irregular vertebral endplates", "Irritability", "Ischemic stroke", "J shaped sella turcica", "Jaundice", "Jerky head movements", "Jerky ocular pursuit movements", "Joint contracture of the 5th finger", "Joint contracture of the hand", "Joint contractures involving the joints of the feet", "Joint dislocation", "Joint hemorrhage", "Joint hyperflexibility", "Joint hypermobility", "Joint laxity", "Joint stiffness", "Joint subluxation", "Joint swelling", "Juvenile aseptic necrosis", "Juvenile cataract", "Juvenile myelomonocytic leukemia", "Juvenile onset", "Juvenile rheumatoid arthritis", "Keloids", "Keratitis", "Keratoconjunctivitis", "Keratosis pilaris", "Ketoacidosis", "Ketonuria", "Ketosis", "Ketotic hypoglycemia", "Kinetic tremor", "Kinked brainstem", "Knee clonus", "Knee dislocation", "Knee flexion contracture", "Kyphoscoliosis", "Kyphosis", "Labial hypertrophy", "Lack of insight", "Lack of peer relationships", "Lack of skin elasticity", "Lack of t cell function", "Lacrimal duct atresia", "Lacrimal duct stenosis", "Lacrimation abnormality", "Lactic acidosis", "Lacticaciduria", "Lactose intolerance", "Lagopthalmos", "Lambdoidal craniosynostosis", "Language impairment", "Large basal ganglia", "Large beaked nose", "Large cafe au lait macules with irregular margins", "Large earlobe", "Large face", "Large fleshy ears", "Large for gestational age", "Large foramen magnum", "Large forehead", "Large hands", "Large intestinal polyposis", "Large placenta", "Large sella turcica", "Laryngeal cleft", "Laryngeal dystonia", "Laryngeal hypoplasia", "Laryngeal stenosis", "Laryngeal stridor", "Laryngomalacia", "Laryngotracheomalacia", "Late onset", "Lateral clavicle hook", "Leber optic atrophy", "Left atrial enlargement", "Left bundle branch block", "Left to right shunt", "Left ventricular hypertrophy", "Left ventricular noncompaction cardiomyopathy", "Left ventricular outflow tract obstruction", "Left ventricular systolic dysfunction", "Leg muscle stiffness", "Leiomyosarcoma", "Lens subluxation", "Lenticonus", "Lethal skeletal dysplasia", "Lethargy", "Leukemia", "Leukocytosis", "Leukodystrophy", "Leukoencephalopathy", "Leukonychia", "Leukopenia", "Lewy bodies", "Leydig cell neoplasia", "Lichenification", "Limb ataxia", "Limb dystonia", "Limb fasciculations", "Limb girdle muscle atrophy", "Limb girdle muscle weakness", "Limb girdle muscular dystrophy", "Limb hypertonia", "Limb joint contracture", "Limb muscle weakness", "Limb myoclonus", "Limb pain", "Limb tremor", "Limb undergrowth", "Limbal dermoid", "Limitation of joint mobility", "Limitation of knee mobility", "Limitation of movement at ankles", "Limitation of neck motion", "Limited elbow extension", "Limited elbow movement", "Limited extraocular movements", "Limited hip extension", "Limited hip movement", "Limited knee extension", "Limited neck range of motion", "Limited wrist extension", "Limited wrist movement", "Lingual dystonia", "Lipid accumulation in hepatocytes", "Lipoatrophy", "Lipodystrophy", "Lipoma", "Lissencephaly", "Liver abscess", "Lobulated tongue", "Localized hirsutism", "Localized osteoporosis", "Localized skin lesion", "Long clavicles", "Long ear", "Long eyelashes", "Long fingers", "Long foot", "Long hallux", "Long neck", "Long nose", "Long palm", "Long palpebral fissure", "Long penis", "Long philtrum", "Long thorax", "Long toe", "Long tract signs", "Lop ear", "Loss of ability to walk", "Loss of consciousness", "Loss of eyelashes", "Loss of purkinje cells in the cerebellar vermis", "Loss of speech", "Loss of subcutaneous adipose tissue in limbs", "Loss of voice", "Low alkaline phosphatase", "Low anterior hairline", "Low apgar score", "Low back pain", "Low frustration tolerance", "Low grade fever", "Low hanging columella", "Low levels of vitamin d", "Low molecular weight proteinuria", "Low plasma citrulline", "Low posterior hairline", "Low serum calcitriol", "Low set nipples", "Low set posteriorly rotated ears", "Lower extremity joint dislocation", "Lower eyelid coloboma", "Lower limb amyotrophy", "Lower limb asymmetry", "Lower limb hyperreflexia", "Lower limb hypertonia", "Lower limb metaphyseal irregularity", "Lower limb muscle weakness", "Lower limb pain", "Lower limb spasticity", "Lower limb undergrowth", "Lumbar hyperlordosis", "Lumbar kyphosis", "Lumbar scoliosis", "Lung adenocarcinoma", "Lymphangiectasis", "Lymphangioma", "Lymphedema", "Lymphocytosis", "Lymphoma", "Lymphopenia", "Lymphoproliferative disorder", "Macrocephaly at birth", "Macrocytic anemia", "Macrodactyly", "Macrodontia", "Macrodontia of permanent maxillary central incisor", "Macroglossia", "Macrogyria", "Macroorchidism", "Macroscopic hematuria", "Macrotia", "Macrovesicular hepatic steatosis", "Macular atrophy", "Macular coloboma", "Macular degeneration", "Macular hyperpigmentation", "Macular hypoplasia", "Macular purpura", "Macular thickening", "Macule", "Malabsorption", "Malar prominence", "Malar rash", "Male hypogonadism", "Male infertility", "Male pseudohermaphroditism", "Male reproductive system neoplasm", "Male sexual dysfunction", "Malignant genitourinary tract tumor", "Malignant hyperthermia", "Malignant neoplasm of the central nervous system", "Malnutrition", "Malrotation of small bowel", "Mandibular aplasia", "Mandibular prognathia", "Mania", "Mask like facies", "Mastoiditis", "Maternal hypertension", "Maturity onset diabetes of the young", "Meconium stained amniotic fluid", "Medial flaring of the eyebrow", "Median cleft lip", "Median cleft palate", "Mediastinal lymphadenopathy", "Medullary nephrocalcinosis", "Medulloblastoma", "Megalencephaly", "Megaloblastic anemia", "Megalocornea", "Melanocytic nevus", "Melanoma", "Melena", "Membranoproliferative glomerulonephritis", "Memory impairment", "Meningioma", "Meningitis", "Meningocele", "Meningoencephalocele", "Menorrhagia", "Mental deterioration", "Mesoaxial hand polydactyly", "Mesoaxial polydactyly", "Mesomelia", "Metabolic acidosis", "Metabolic alkalosis", "Metacarpophalangeal joint contracture", "Metamorphopsia", "Metaphyseal chondrodysplasia", "Metaphyseal cupping", "Metaphyseal dysplasia", "Metaphyseal irregularity", "Metaphyseal sclerosis", "Metaphyseal spurs", "Metaphyseal striations", "Metaphyseal widening", "Metatarsal synostosis", "Metatarsus adductus", "Metatarsus valgus", "Methemoglobinemia", "Methylmalonic acidemia", "Methylmalonic aciduria", "Metopic synostosis", "Metrorrhagia", "Microcornea", "Microcytic anemia", "Microdontia", "Microglossia", "Micrographia", "Micromelia", "Micronodular cirrhosis", "Micropenis", "Microphallus", "Microretrognathia", "Microscopic hematuria", "Microtia third degree", "Microvesicular hepatic steatosis", "Middle age onset", "Midface retrusion", "Midline defect of the nose", "Migraine", "Mild global developmental delay", "Mild hearing impairment", "Mild microcephaly", "Mild postnatal growth retardation", "Mild short stature", "Mildly elevated creatine kinase", "Milia", "Minicore myopathy", "Minimal change glomerulonephritis", "Miosis", "Misalignment of incisors", "Missing ribs", "Mitochondrial inheritance", "Mitochondrial myopathy", "Mitochondrial respiratory chain defects", "Mitral stenosis", "Mitral valve calcification", "Mitral valve prolapse", "Mitten deformity", "Mixed demyelinating and axonal polyneuropathy", "Mixed hearing impairment", "Mixed hypo and hyperpigmentation of the skin", "Moderate albuminuria", "Moderate global developmental delay", "Moderate sensorineural hearing impairment", "Moderately reduced visual acuity", "Moderately short stature", "Molar tooth sign on mri", "Molluscoid pseudotumors", "Molluscum contagiosum", "Monochromacy", "Monocytosis", "Monotonic speech", "Mood swings", "Morning glory anomaly", "Morning myoclonic jerks", "Morphological abnormality of the corticospinal tract", "Morphological abnormality of the middle ear", "Morphological abnormality of the pyramidal tract", "Morphological abnormality of the vestibule of the inner ear", "Mortality aging", "Motor axonal neuropathy", "Motor delay", "Motor deterioration", "Motor neuron atrophy", "Motor polyneuropathy", "Motor regression", "Motor seizure", "Motor tics", "Mottled pigmentation", "Movement abnormality of the tongue", "Moyamoya phenomenon", "Mucosal telangiectasiae", "Multicystic kidney dysplasia", "Multifactorial inheritance", "Multifocal cerebral white matter abnormalities", "Multifocal epileptiform discharges", "Multifocal seizures", "Multiple cafe au lait spots", "Multiple enchondromatosis", "Multiple epiphyseal dysplasia", "Multiple exostoses", "Multiple gastric polyps", "Multiple glomerular cysts", "Multiple impacted teeth", "Multiple joint contractures", "Multiple joint dislocation", "Multiple lentigines", "Multiple lipomas", "Multiple mitochondrial dna deletions", "Multiple myeloma", "Multiple prenatal fractures", "Multiple renal cysts", "Multiple rib fractures", "Multiple rows of eyelashes", "Multiple suture craniosynostosis", "Muscle abnormality related to mitochondrial dysfunction", "Muscle fiber atrophy", "Muscle fiber inclusion bodies", "Muscle fiber necrosis", "Muscle fiber splitting", "Muscle fiber tubular inclusions", "Muscle fibrillation", "Muscle flaccidity", "Muscle hypertrophy of the lower extremities", "Muscle spasm", "Muscle stiffness", "Muscle weakness", "Muscular dystrophy", "Muscular hypotonia of the trunk", "Muscular ventricular septal defect", "Mutism", "Myalgia", "Mydriasis", "Myelodysplasia", "Myelofibrosis", "Myeloid leukemia", "Myelomeningocele", "Myelopathy", "Myeloproliferative disorder", "Myocardial fibrosis", "Myoclonic seizure", "Myoclonic spasms", "Myoclonus", "Myofibrillar myopathy", "Myoglobinuria", "Myokymia", "Myopathic facies", "Myopathy", "Myopia", "Myositis", "Myotonia", "Naevus flammeus of the eyelid", "Nail dysplasia", "Nail dystrophy", "Nail pits", "Narrow face", "Narrow foot", "Narrow foramen obturatorium", "Narrow forehead", "Narrow iliac wing", "Narrow internal auditory canal", "Narrow jaw", "Narrow mouth", "Narrow nasal bridge", "Narrow nasal ridge", "Narrow nose", "Narrow palate", "Narrow palm", "Narrow palpebral fissure", "Narrow pelvis bone", "Narrow vertebral interpedicular distance", "Nasal congestion", "Nasal regurgitation", "Nasal speech", "Nasogastric tube feeding", "Nasogastric tube feeding in infancy", "Nasolacrimal duct obstruction", "Natal tooth", "Nausea", "Nausea and vomiting", "Neck flexor weakness", "Neck muscle weakness", "Negativism", "Nemaline bodies", "Neonatal alloimmune thrombocytopenia", "Neonatal asphyxia", "Neonatal breathing dysregulation", "Neonatal death", "Neonatal hyperbilirubinemia", "Neonatal hypoglycemia", "Neonatal hypotonia", "Neonatal insulin dependent diabetes mellitus", "Neonatal onset", "Neonatal respiratory distress", "Neoplasm", "Neoplasm by histology", "Neoplasm of fatty tissue", "Neoplasm of head and neck", "Neoplasm of striated muscle", "Neoplasm of the adrenal cortex", "Neoplasm of the adrenal gland", "Neoplasm of the breast", "Neoplasm of the colon", "Neoplasm of the ear", "Neoplasm of the endocrine system", "Neoplasm of the eye", "Neoplasm of the gallbladder", "Neoplasm of the gastrointestinal tract", "Neoplasm of the genitourinary tract", "Neoplasm of the heart", "Neoplasm of the inner ear", "Neoplasm of the large intestine", "Neoplasm of the larynx", "Neoplasm of the liver", "Neoplasm of the male external genitalia", "Neoplasm of the middle ear", "Neoplasm of the nervous system", "Neoplasm of the oral cavity", "Neoplasm of the pancreas", "Neoplasm of the parathyroid gland", "Neoplasm of the peripheral nervous system", "Neoplasm of the pituitary gland", "Neoplasm of the rectum", "Neoplasm of the respiratory system", "Neoplasm of the skeletal system", "Neoplasm of the skin", "Neoplasm of the small intestine", "Neoplasm of the stomach", "Neoplasm of the thymus", "Neoplasm of the thyroid gland", "Neoplasm of the tongue", "Neoplasm of the tracheobronchial system", "Nephritis", "Nephrocalcinosis", "Nephrolithiasis", "Nephronophthisis", "Nephropathy", "Nephrotic syndrome", "Neuralgia", "Neurodegeneration", "Neuroendocrine neoplasm", "Neurofibrillary tangles", "Neurofibromas", "Neurogenic bladder", "Neuroinflammation", "Neuroma", "Neuromuscular dysphagia", "Neuronal loss in basal ganglia", "Neuronal loss in central nervous system", "Neuronal loss in the cerebral cortex", "Neuropathic arthropathy", "Neutropenia in presence of anti neutropil antibodies", "Nevus", "Night sweats", "No social interaction", "Nocturia", "Nocturnal hypoventilation", "Nocturnal seizures", "Nodular goiter", "Non convulsive status epilepticus without coma", "Non hodgkin lymphoma", "Non medullary thyroid carcinoma", "Non midline cleft lip", "Non midline cleft palate", "Non motor seizure", "Non obstructive azoospermia", "Noncommunicating hydrocephalus", "Noncompaction cardiomyopathy", "Nonimmune hydrops fetalis", "Nonketotic hypoglycemia", "Nonprogressive", "Nonprogressive cerebellar ataxia", "Nonprogressive encephalopathy", "Nonspherocytic hemolytic anemia", "Normochromic anemia", "Normocytic anemia", "Nuclear cataract", "Numerous nevi", "Numerous pigmented freckles", "Nyctalopia", "Nystagmus induced head nodding", "Obsessive compulsive behavior", "Obsessive compulsive trait", "Obstructive sleep apnea", "Occipital cortical atrophy", "Occipital encephalocele", "Occipital meningocele", "Ocular albinism", "Ocular anterior segment dysgenesis", "Ocular pain", "Oculogyric crisis", "Oculomotor apraxia", "Oculomotor nerve palsy", "Odontogenic neoplasm", "Oligoarthritis", "Oligodactyly", "Oligodontia", "Oligohydramnios", "Oligomenorrhea", "Oligosacchariduria", "Oligospermia", "Oliguria", "Olivopontocerebellar atrophy", "Olivopontocerebellar hypoplasia", "Omphalocele", "Onion bulb formation", "Onset", "Onychogryposis", "Onychogryposis of toenails", "Onycholysis", "Onychomycosis", "Open angle glaucoma", "Open bite", "Open mouth", "Open operculum", "Ophthalmoparesis", "Opisthotonus", "Opportunistic infection", "Opsoclonus", "Optic atrophy", "Optic disc coloboma", "Optic disc hypoplasia", "Optic disc pallor", "Optic nerve compression", "Optic nerve dysplasia", "Optic nerve hypoplasia", "Optic neuropathy", "Oral aversion", "Oral cavity bleeding", "Oral cleft", "Oral leukoplakia", "Oral mucosal blisters", "Oral pharyngeal dysphagia", "Oral ulcer", "Orchitis", "Organic aciduria", "Orofacial dyskinesia", "Oromandibular dystonia", "Oromotor apraxia", "Oroticaciduria", "Orthopnea", "Orthostatic hypotension", "Orthostatic hypotension due to autonomic dysfunction", "Osteoarthritis", "Osteochondroma", "Osteochondrosis", "Osteolysis", "Osteolysis involving bones of the feet", "Osteolysis involving bones of the upper limbs", "Osteolytic defects of the distal phalanges of the hand", "Osteomalacia", "Osteomyelitis", "Osteopenia", "Osteopetrosis", "Osteoporosis", "Osteosarcoma", "Otitis media", "Otosclerosis", "Oval face", "Ovarian carcinoma", "Ovarian cyst", "Ovarian gonadoblastoma", "Ovarian neoplasm", "Ovarian papillary adenocarcinoma", "Overfolding of the superior helices", "Overfriendliness", "Overgrowth", "Overhanging nasal tip", "Overlapping fingers", "Overlapping toe", "Overriding aorta", "Overtubulated long bones", "Overweight", "Ovoid vertebral bodies", "Ovotestis", "Oxycephaly", "Pace of progression", "Pain", "Pain in head and neck region", "Pain insensitivity", "Painless fractures due to injury", "Palate fistula", "Pallor", "Palmar hyperhidrosis", "Palmar pits", "Palmar telangiectasia", "Palmoplantar blistering", "Palmoplantar cutis laxa", "Palmoplantar hyperhidrosis", "Palpebral edema", "Palpitations", "Pancreatic adenocarcinoma", "Pancreatic calcification", "Pancreatic cysts", "Pancreatic endocrine tumor", "Pancreatic fibrosis", "Pancreatic hypoplasia", "Pancreatic islet cell adenoma", "Pancreatic islet cell hyperplasia", "Pancreatitis", "Pancytopenia", "Panhypogammaglobulinemia", "Panhypopituitarism", "Panniculitis", "Papillary renal cell carcinoma", "Papillary thyroid carcinoma", "Papilledema", "Papilloma", "Papule", "Paracentral scotoma", "Paraganglioma", "Parakeratosis", "Paralysis", "Paranoia", "Paraparesis", "Paraplegia", "Paraplegia paraparesis", "Parasomnia", "Parathyroid adenoma", "Parathyroid carcinoma", "Parathyroid hyperplasia", "Paresthesia", "Parietal bossing", "Parietal cortical atrophy", "Parietal foramina", "Parkinsonism", "Parkinsonism with favorable response to dopaminergic medication", "Paronychia", "Paroxysmal bursts of laughter", "Paroxysmal dystonia", "Paroxysmal involuntary eye movements", "Paroxysmal ventricular tachycardia", "Partial absence of thumb", "Partial agenesis of the corpus callosum", "Partial albinism", "Partial anomalous pulmonary venous return", "Partial duplication of the distal phalanges of the hand", "Partial duplication of the phalanx of hand", "Patchy alopecia", "Patchy changes of bone mineral density", "Patchy hypopigmentation of hair", "Patchy palmoplantar hyperkeratosis", "Patellar aplasia", "Patellar dislocation", "Patellar hypoplasia", "Patellar subluxation", "Patent ductus arteriosus", "Patent foramen ovale", "Pathologic fracture", "Pectus carinatum", "Pectus excavatum", "Pectus excavatum of inferior sternum", "Pedal edema", "Pediatric onset", "Peg shaped maxillary lateral incisors", "Pelvic girdle muscle weakness", "Pelvic kidney", "Pendular nystagmus", "Penetrating foot ulcers", "Penoscrotal hypospadias", "Peptic ulcer", "Periauricular skin pits", "Pericardial effusion", "Pericarditis", "Perifoveal ring of hyperautofluorescence", "Perimembranous ventricular septal defect", "Perineal fistula", "Periodic paralysis", "Periodontitis", "Periorbital edema", "Periorbital fullness", "Peripheral arterial stenosis", "Peripheral axonal degeneration", "Peripheral axonal neuropathy", "Peripheral cyanosis", "Peripheral demyelination", "Peripheral edema", "Peripheral hypermyelination", "Peripheral hypomyelination", "Peripheral neuropathy", "Peripheral opacification of the cornea", "Peripheral pulmonary artery stenosis", "Peripheral retinal avascularization", "Peripheral visual field loss", "Periportal fibrosis", "Perisylvian polymicrogyria", "Peritoneal abscess", "Peritonitis", "Periventricular cysts", "Periventricular heterotopia", "Periventricular leukomalacia", "Periventricular nodular heterotopia", "Periventricular white matter hyperintensities", "Peroneal muscle atrophy", "Perseveration", "Persistence of hemoglobin f", "Persistence of primary teeth", "Persistent ebv viremia", "Persistent head lag", "Personality changes", "Personality disorder", "Pes cavus", "Pes planus", "Pes valgus", "Petechiae", "Peters anomaly", "Phalangeal dislocation", "Pharyngitis", "Phenotypic variability", "Pheochromocytoma", "Phimosis", "Phocomelia", "Phonophobia", "Photophobia", "Photopsia", "Photoreceptor layer loss on macular oct", "Photosensitive myoclonic seizure", "Photosensitive tonic clonic seizure", "Phthisis bulbi", "Physical urticaria", "Pierre robin sequence", "Pigmentary retinopathy", "Pili canaliculi", "Pili torti", "Pilomatrixoma", "Pineal cyst", "Pituitary adenoma", "Pituitary growth hormone cell adenoma", "Pituitary hypothyroidism", "Pituitary prolactin cell adenoma", "Plagiocephaly", "Plantar hyperkeratosis", "Platybasia", "Platyspondyly", "Pleural effusion", "Pleuritis", "Pneumonia", "Pneumothorax", "Poikilocytosis", "Poikiloderma", "Pointed chin", "Polar cataract", "Pollakisuria", "Polyarticular arthropathy", "Polyclonal elevation of igm", "Polycystic kidney dysplasia", "Polycystic liver disease", "Polycythemia", "Polydactyly", "Polygenic inheritance", "Polyhydramnios", "Polymicrogyria", "Polyneuropathy", "Polyphagia", "Polysplenia", "Polyuria", "Pontocerebellar atrophy", "Poor appetite", "Poor coordination", "Poor eye contact", "Poor fine motor coordination", "Poor gross motor coordination", "Poor head control", "Poor motor coordination", "Poor speech", "Poor suck", "Poor wound healing", "Popliteal pterygium", "Porencephalic cyst", "Porokeratosis", "Porphyrinuria", "Portal fibrosis", "Portal vein thrombosis", "Positional foot deformity", "Positive romberg sign", "Post partum hemorrhage", "Postaxial foot polydactyly", "Postaxial hand polydactyly", "Postaxial polydactyly", "Posterior blepharitis", "Posterior embryotoxon", "Posterior fossa cyst", "Posterior pharyngeal cleft", "Posterior pituitary dysgenesis", "Posterior polar cataract", "Posterior subcapsular cataract", "Posteriorly rotated ears", "Postexertional malaise", "Postnatal growth retardation", "Postural instability", "Postural tremor", "Potter facies", "Preauricular skin tag", "Preaxial foot polydactyly", "Preaxial hand polydactyly", "Preaxial polydactyly", "Precocious atherosclerosis", "Predominantly lower limb lymphedema", "Prelingual sensorineural hearing impairment", "Premature adrenarche", "Premature arteriosclerosis", "Premature birth", "Premature coronary artery atherosclerosis", "Premature graying of hair", "Premature loss of primary teeth", "Premature loss of teeth", "Premature osteoarthritis", "Premature ovarian insufficiency", "Premature pubarche", "Premature rupture of membranes", "Premature skin wrinkling", "Premature thelarche", "Premature ventricular contraction", "Prematurely aged appearance", "Prenatal maternal abnormality", "Prenatal movement abnormality", "Primary adrenal insufficiency", "Primary amenorrhea", "Primary congenital glaucoma", "Primary gonadal insufficiency", "Primary hypercortisolism", "Primary hyperparathyroidism", "Primary microcephaly", "Primary peritoneal carcinoma", "Primitive neuroectodermal tumor", "Primitive reflex", "Productive cough", "Profound global developmental delay", "Profound hearing impairment", "Profound sensorineural hearing impairment", "Progeroid facial appearance", "Progressive", "Progressive cerebellar ataxia", "Progressive distal muscle weakness", "Progressive encephalopathy", "Progressive external ophthalmoplegia", "Progressive extrapyramidal movement disorder", "Progressive flexion contractures", "Progressive gait ataxia", "Progressive hearing impairment", "Progressive inability to walk", "Progressive leukoencephalopathy", "Progressive macrocephaly", "Progressive microcephaly", "Progressive muscle weakness", "Progressive neurologic deterioration", "Progressive night blindness", "Progressive peripheral neuropathy", "Progressive pes cavus", "Progressive proximal muscle weakness", "Progressive psychomotor deterioration", "Progressive pulmonary function impairment", "Progressive sensorineural hearing impairment", "Progressive spastic paraparesis", "Progressive spastic paraplegia", "Progressive spastic quadriplegia", "Progressive spasticity", "Progressive visual field defects", "Progressive visual loss", "Prolinuria", "Prolonged bleeding after dental extraction", "Prolonged bleeding after surgery", "Prolonged bleeding following circumcision", "Prolonged bleeding following procedure", "Prolonged bleeding time", "Prolonged neonatal jaundice", "Prolonged partial thromboplastin time", "Prolonged qtc interval", "Prominent antihelix", "Prominent antitragus", "Prominent calcaneus", "Prominent coccyx", "Prominent crus of helix", "Prominent digit pad", "Prominent ear helix", "Prominent eyelashes", "Prominent forehead", "Prominent metopic ridge", "Prominent nasal bridge", "Prominent nasal tip", "Prominent nasolabial fold", "Prominent nose", "Prominent occiput", "Prominent sternum", "Prominent superficial blood vessels", "Prominent supraorbital ridges", "Prominent umbilicus", "Prominent veins on trunk", "Proportionate short stature", "Proportionate tall stature", "Proptosis", "Prostate neoplasm", "Protein avoidance", "Protein losing enteropathy", "Protracted diarrhea", "Protruding ear", "Protruding tongue", "Protrusio acetabuli", "Protuberant abdomen", "Proximal amyotrophy", "Proximal femoral epiphysiolysis", "Proximal femoral metaphyseal abnormality", "Proximal femoral metaphyseal irregularity", "Proximal muscle weakness", "Proximal muscle weakness in lower limbs", "Proximal muscle weakness in upper limbs", "Proximal renal tubular acidosis", "Proximal symphalangism", "Proximal tubulopathy", "Proximal upper limb amyotrophy", "Pruritus", "Pseudoarthrosis", "Pseudobulbar paralysis", "Pseudobulbar signs", "Pseudoepiphyses", "Pseudoepiphyses of hand bones", "Pseudoepiphyses of the metacarpals", "Pseudohypoaldosteronism", "Pseudohypoparathyroidism", "Psoriasiform dermatitis", "Psychogenic non epileptic seizure", "Psychomotor deterioration", "Psychomotor retardation", "Psychosis", "Psychotic episodes", "Psychotic mentation", "Pterygium", "Ptosis", "Puberty and gonadal disorders", "Pulmonary artery atresia", "Pulmonary artery dilatation", "Pulmonary artery hypoplasia", "Pulmonary artery stenosis", "Pulmonary carcinoid tumor", "Pulmonary cyst", "Pulmonary edema", "Pulmonary embolism", "Pulmonary fibrosis", "Pulmonary hemorrhage", "Pulmonary hypoplasia", "Pulmonary infiltrates", "Pulmonary insufficiency", "Pulmonary interstitial high resolution computed tomography abnormality", "Pulmonary venous hypertension", "Pulmonic stenosis", "Pulverulent cataract", "Punctate cataract", "Pure red cell aplasia", "Purpura", "Pustule", "Pyelonephritis", "Pyoderma gangrenosum", "Pyridoxine responsive sideroblastic anemia", "Quadriceps muscle weakness", "Radial bowing", "Radial deviation of the 2nd finger", "Radial deviation of the hand", "Radial deviation of the hand or of fingers of the hand", "Radioulnar dislocation", "Radioulnar synostosis", "Ragged red muscle fibers", "Rapidly progressive", "Raynaud phenomenon", "Reactive hypoglycemia", "Receptive language delay", "Rectal fistula", "Rectal prolapse", "Recurrent", "Recurrent abscess formation", "Recurrent acute respiratory tract infection", "Recurrent aspergillus infections", "Recurrent aspiration pneumonia", "Recurrent bacterial infections", "Recurrent bacterial skin infections", "Recurrent bronchitis", "Recurrent bronchopulmonary infections", "Recurrent corneal erosions", "Recurrent cutaneous abscess formation", "Recurrent ear infections", "Recurrent fever", "Recurrent fractures", "Recurrent gastroenteritis", "Recurrent hand flapping", "Recurrent herpes", "Recurrent hypoglycemia", "Recurrent infection of the gastrointestinal tract", "Recurrent joint dislocation", "Recurrent lower respiratory tract infections", "Recurrent mycobacterial infections", "Recurrent opportunistic infections", "Recurrent otitis media", "Recurrent pancreatitis", "Recurrent paroxysmal headache", "Recurrent pharyngitis", "Recurrent pneumonia", "Recurrent respiratory infections", "Recurrent sinopulmonary infections", "Recurrent sinusitis", "Recurrent skin infections", "Recurrent spontaneous abortion", "Recurrent staphylococcal infections", "Recurrent staphylococcus aureus infections", "Recurrent tonsillitis", "Recurrent upper and lower respiratory tract infections", "Recurrent urinary tract infections", "Recurrent viral infections", "Red eye", "Red green dyschromatopsia", "Red hair", "Reduced antigen specific t cell proliferation", "Reduced antithrombin iii activity", "Reduced brain n acetyl aspartate level by mrs", "Reduced c peptide level", "Reduced circulating prolactin concentration", "Reduced consciousness confusion", "Reduced delayed hypersensitivity", "Reduced factor viii activity", "Reduced factor xi activity", "Reduced factor xii activity", "Reduced factor xiii activity", "Reduced forced expiratory volume in one second", "Reduced forced vital capacity", "Reduced natural killer cell count", "Reduced protein c activity", "Reduced protein s activity", "Reduced renal corticomedullary differentiation", "Reduced sperm motility", "Reduced subcutaneous adipose tissue", "Reduced systolic function", "Reduced tendon reflexes", "Reduced visual acuity", "Reduced vital capacity", "Reduction of neutrophil motility", "Redundant neck skin", "Redundant skin", "Reflex seizure", "Refractory anemia", "Regional abnormality of skin", "Relative macrocephaly", "Remnants of the hyaloid vascular system", "Renal agenesis", "Renal angiomyolipoma", "Renal cell carcinoma", "Renal cortical cysts", "Renal cortical microcysts", "Renal corticomedullary cysts", "Renal cyst", "Renal duplication", "Renal dysplasia", "Renal fanconi syndrome", "Renal fibrosis", "Renal hamartoma", "Renal hypoplasia", "Renal hypoplasia aplasia", "Renal insufficiency", "Renal magnesium wasting", "Renal malrotation", "Renal phosphate wasting", "Renal potassium wasting", "Renal salt wasting", "Renal sodium wasting", "Renal steatosis", "Renal tubular acidosis", "Renal tubular atrophy", "Renal tubular dysfunction", "Renal tubular epithelial necrosis", "Renovascular hypertension", "Repetitive compulsive behavior", "Respiratory alkalosis", "Respiratory arrest", "Respiratory distress", "Respiratory failure", "Respiratory failure requiring assisted ventilation", "Respiratory insufficiency", "Respiratory insufficiency due to defective ciliary clearance", "Respiratory paralysis", "Respiratory tract infection", "Response to drugs acting on neuromuscular transmission", "Resting tremor", "Restless legs", "Restlessness", "Restrictive behavior", "Restrictive cardiomyopathy", "Restrictive ventilatory defect", "Reticular hyperpigmentation", "Reticulated skin pigmentation", "Reticulocytopenia", "Reticulocytosis", "Retinal arterial tortuosity", "Retinal arteriolar tortuosity", "Retinal atrophy", "Retinal coloboma", "Retinal degeneration", "Retinal detachment", "Retinal dysplasia", "Retinal dystrophy", "Retinal fold", "Retinal hamartoma", "Retinal hemorrhage", "Retinal neovascularization", "Retinal nonattachment", "Retinal perforation", "Retinal pigment epithelial atrophy", "Retinal pigment epithelial mottling", "Retinal telangiectasia", "Retinal thinning", "Retinal vascular tortuosity", "Retinopathy", "Retrocollis", "Retrognathia", "Rhabdomyolysis", "Rhabdomyosarcoma", "Rhegmatogenous retinal detachment", "Rheumatoid arthritis", "Rheumatoid factor positive", "Rhinitis", "Rhizomelia", "Rhizomelic arm shortening", "Rib fusion", "Rib segmentation abnormalities", "Rickets", "Ridged nail", "Rieger anomaly", "Right aortic arch with mirror image branching", "Right bundle branch block", "Right ventricular cardiomyopathy", "Right ventricular dilatation", "Right ventricular hypertrophy", "Rigidity", "Rimmed vacuoles", "Rod cone dystrophy", "Rotary nystagmus", "Round ear", "Round face", "Saccadic oscillation", "Saccadic smooth pursuit", "Sacrococcygeal teratoma", "Sagittal craniosynostosis", "Sandal gap", "Sarcoma", "Scaling skin", "Scanning speech", "Scaphocephaly", "Scapular winging", "Scarring", "Scarring alopecia of scalp", "Schistocytosis", "Schizencephaly", "Schizophrenia", "Schwannoma", "Scleral staphyloma", "Sclerocornea", "Scleroderma", "Sclerosis of hand bone", "Sclerosis of skull base", "Sclerotic vertebral endplates", "Scotoma", "Scrotal hypoplasia", "Sea blue histiocytosis", "Seborrheic dermatitis", "Second degree atrioventricular block", "Secondary amenorrhea", "Secondary growth hormone deficiency", "Secondary microcephaly", "Secretory diarrhea", "Secundum atrial septal defect", "Segmental peripheral demyelination remyelination", "Selective tooth agenesis", "Self injurious behavior", "Self mutilation", "Semilobar holoprosencephaly", "Senile plaques", "Sensorimotor neuropathy", "Sensory ataxia", "Sensory axonal neuropathy", "Sensory neuropathy", "Sepsis", "Septate vagina", "Septic arthritis", "Septo optic dysplasia", "Serositis", "Severe b lymphocytopenia", "Severe combined immunodeficiency", "Severe cytomegalovirus infection", "Severe demyelination of the white matter", "Severe expressive language delay", "Severe failure to thrive", "Severe global developmental delay", "Severe hearing impairment", "Severe infection", "Severe intrauterine growth retardation", "Severe lactic acidosis", "Severe muscular hypotonia", "Severe photosensitivity", "Severe postnatal growth retardation", "Severe short limb dwarfism", "Severe short stature", "Severe varicella zoster infection", "Severe viral infection", "Severely reduced visual acuity", "Sex reversal", "Shagreen patch", "Shallow acetabular fossae", "Shallow anterior chamber", "Shallow orbits", "Shawl scrotum", "Shield chest", "Shock", "Short 1st metacarpal", "Short attention span", "Short chin", "Short clavicles", "Short columella", "Short digit", "Short face", "Short femur", "Short foot", "Short fourth metatarsal", "Short lingual frenulum", "Short long bone", "Short lower limbs", "Short middle phalanx of finger", "Short middle phalanx of the 2nd finger", "Short middle phalanx of toe", "Short nail", "Short nose", "Short palm", "Short palpebral fissure", "Short phalanx of the thumb", "Short philtrum", "Short proximal phalanx of finger", "Short ribs", "Short stepped shuffling gait", "Short sternum", "Short thorax", "Short thumb", "Short tibia", "Short umbilical cord", "Short upper lip", "Shortened pr interval", "Shortened qt interval", "Shortening of all distal phalanges of the fingers", "Shortening of all middle phalanges of the fingers", "Shoulder dislocation", "Shoulder girdle muscle atrophy", "Shoulder girdle muscle weakness", "Shoulder pain", "Shuffling gait", "Shyness", "Sick sinus syndrome", "Sideroblastic anemia", "Simple ear", "Simple febrile seizure", "Simplified gyral pattern", "Single fiber emg abnormality", "Single naris", "Single transverse palmar crease", "Single ventricle", "Sinus bradycardia", "Sinus tachycardia", "Sirenomelia", "Skeletal dysplasia", "Skeletal muscle atrophy", "Skeletal muscle hypertrophy", "Skeletal myopathy", "Skin appendage neoplasm", "Skin dimple", "Skin erosion", "Skin nodule", "Skin picking", "Skin pit", "Skin plaque", "Skin rash", "Skin tags", "Skin ulcer", "Skin vesicle", "Skull asymmetry", "Slanting of the palpebral fissure", "Sleep apnea", "Sleep disturbance", "Sleep wake cycle disturbance", "Slender build", "Slender finger", "Slender long bone", "Slender toe", "Sloping forehead", "Slow decrease in visual acuity", "Slow pupillary light response", "Slow saccadic eye movements", "Slowly progressive", "Slurred speech", "Small anterior fontanelle", "Small basal ganglia", "Small cerebral cortex", "Small earlobe", "Small epiphyses", "Small face", "Small for gestational age", "Small hand", "Small intestinal dysmotility", "Small nail", "Small pituitary gland", "Small placenta", "Smooth muscle antibody positivity", "Smooth philtrum", "Snoring", "Social and occupational deterioration", "Soft doughy skin", "Soft skin", "Soft tissue neoplasm", "Soft tissue sarcoma", "Solitary median maxillary central incisor", "Somatic mosaicism", "Somatic mutation", "Somatic sensory dysfunction", "Sound sensitivity", "Sparse and thin eyebrow", "Sparse body hair", "Sparse eyebrow", "Sparse eyelashes", "Sparse hair", "Sparse lateral eyebrow", "Sparse or absent eyelashes", "Sparse scalp hair", "Spastic ataxia", "Spastic diplegia", "Spastic dysarthria", "Spastic gait", "Spastic hyperactive bladder", "Spastic paraparesis", "Spastic paraparetic gait", "Spastic paraplegia", "Spastic tetraparesis", "Spastic tetraplegia", "Spasticity", "Specific learning disability", "Speech apraxia", "Speech articulation difficulties", "Spider hemangioma", "Spina bifida", "Spina bifida occulta", "Spinal canal stenosis", "Spinal cord compression", "Spinal cord lesion", "Spinal cord tumor", "Spinal deformities", "Spinal muscular atrophy", "Spinal rigidity", "Spinocerebellar tract degeneration", "Splanchnic vein thrombosis", "Splenomegaly", "Split nail", "Spoken word recognition deficit", "Spondyloepimetaphyseal dysplasia", "Spondyloepiphyseal dysplasia", "Spondylolisthesis", "Spondylolysis", "Spontaneous abortion", "Spontaneous hematomas", "Spontaneous hemolytic crises", "Spontaneous pain sensation", "Spontaneous recurrent epistaxis", "Sporadic", "Spotty hyperpigmentation", "Spotty hypopigmentation", "Sprengel anomaly", "Squamous cell carcinoma", "Squamous cell carcinoma of the skin", "Square face", "Squared iliac bones", "St segment elevation", "Stage 5 chronic kidney disease", "Stapes ankylosis", "Staring gaze", "Status epilepticus", "Status epilepticus with prominent motor symptoms", "Status epilepticus without prominent motor symptoms", "Stenosis of the external auditory canal", "Steppage gait", "Stereotypical body rocking", "Stereotypical hand wringing", "Stereotypy", "Steroid resistant nephrotic syndrome", "Stiff skin", "Stillbirth", "Stomach cancer", "Stomatitis", "Stomatocytosis", "Stooped posture", "Streak ovary", "Striae distensae", "Stridor", "Stroke", "Stroke like episode", "Stuttering", "Subacute progressive viral hepatitis", "Subarachnoid hemorrhage", "Subcapsular cataract", "Subcortical band heterotopia", "Subcortical cerebral atrophy", "Subcortical heterotopia", "Subcutaneous hemorrhage", "Subcutaneous lipoma", "Subcutaneous nodule", "Subdural hemorrhage", "Subependymal cysts", "Subglottic stenosis", "Submucous cleft of soft and hard palate", "Submucous cleft soft palate", "Subretinal fluid", "Subsarcolemmal accumulations of abnormally shaped mitochondria", "Substantia nigra gliosis", "Subvalvular aortic stenosis", "Sudden death", "Sudden episodic apnea", "Sudden loss of visual acuity", "Suicidal ideation", "Sunken cheeks", "Supernumerary bones of the axial skeleton", "Supernumerary nipple", "Supernumerary spleens", "Supernumerary tooth", "Supranuclear gaze palsy", "Supranuclear ophthalmoplegia", "Supravalvular aortic stenosis", "Supraventricular arrhythmia", "Supraventricular tachycardia", "Swan neck like deformities of the fingers", "Symphalangism affecting the phalanges of the hand", "Symphalangism of middle phalanx of finger", "Symptomatic seizures", "Syncope", "Syndactyly", "Synostosis involving bones of the hand", "Synostosis involving bones of the lower limbs", "Synostosis involving bones of the upper limbs", "Synostosis involving digits", "Synostosis of carpal bones", "Synostosis of carpals tarsals", "Synostosis of joints", "Synostosis of metacarpals metatarsals", "Synovitis", "Syringomyelia", "Systemic lupus erythematosus", "T cell lymphoma", "T lymphocytopenia", "Tachycardia", "Tachypnea", "Talipes calcaneovalgus", "Talipes equinovalgus", "Talipes equinovarus", "Talipes valgus", "Tall chin", "Tall stature", "Tapered distal phalanges of finger", "Tapered finger", "Tarsal synostosis", "Telangiectasia", "Telangiectasia of the skin", "Telecanthus", "Temperature instability", "Temporal cortical atrophy", "Temporal optic disc pallor", "Temporal pattern", "Tendon xanthomatosis", "Tented upper lip vermilion", "Teratoma", "Testicular adrenal rest tumor", "Testicular atrophy", "Testicular dysgenesis", "Tetany", "Tetralogy of fallot", "Tetraparesis", "Tetraplegia", "Tetraplegia tetraparesis", "Thenar muscle atrophy", "Thick cerebral cortex", "Thick corpus callosum", "Thick eyebrow", "Thick hair", "Thick lower lip vermilion", "Thick nasal alae", "Thick upper lip vermilion", "Thick vermilion border", "Thickened calvaria", "Thickened cortex of long bones", "Thickened ears", "Thickened helices", "Thickened nuchal skin fold", "Thickened ribs", "Thickened skin", "Thin bony cortex", "Thin clavicles", "Thin eyebrow", "Thin lower lip vermilion", "Thin nail", "Thin ribs", "Thin skin", "Thin upper lip vermilion", "Thin vermilion border", "Third degree atrioventricular block", "Thoracic aortic aneurysm", "Thoracic hypoplasia", "Thoracic kyphoscoliosis", "Thoracic kyphosis", "Thoracic scoliosis", "Thoracolumbar kyphoscoliosis", "Thoracolumbar kyphosis", "Thoracolumbar scoliosis", "Thrombocytosis", "Thromboembolism", "Thrombophlebitis", "Thymus hyperplasia", "Thyroid adenoma", "Thyroid carcinoma", "Thyroiditis", "Tibial bowing", "Tibial torsion", "Tibialis muscle weakness", "Tics", "Tiger tail banding", "Tinnitus", "Tip toe gait", "Tissue ischemia", "Titubation", "Toe clinodactyly", "Toe syndactyly", "Toe walking", "Toenail dysplasia", "Tongue atrophy", "Tongue fasciculations", "Tongue nodules", "Tongue thrusting", "Tonic seizure", "Tooth abscess", "Tooth malposition", "Torsade de pointes", "Torsion dystonia", "Total anomalous pulmonary venous return", "Toxemia of pregnancy", "Tracheal stenosis", "Tracheobronchomalacia", "Tracheoesophageal fistula", "Tracheomalacia", "Tractional retinal detachment", "Transient global amnesia", "Transient ischemic attack", "Transient neutropenia", "Transposition of the great arteries", "Tremor", "Tremor by anatomical site", "Triangular face", "Triangular mouth", "Triangular shaped phalanges of the hand", "Trichorrhexis nodosa", "Tricuspid atresia", "Tricuspid stenosis", "Tricuspid valve prolapse", "Trigonocephaly", "Triphalangeal thumb", "Trismus", "Tritanomaly", "Trophic changes related to pain", "Truncal ataxia", "Truncal obesity", "Truncal titubation", "Truncus arteriosus", "Tube feeding", "Tubulointerstitial nephritis", "Turricephaly", "Type 1 fibers relatively smaller than type 2 fibers", "Type 1 muscle fiber atrophy", "Type 2 muscle fiber atrophy", "Type 2 muscle fiber predominance", "Type i diabetes mellitus", "Type i transferrin isoform profile", "Type ii diabetes mellitus", "Type ii lissencephaly", "Type ii transferrin isoform profile", "Typical absence seizure", "U shaped upper lip vermilion", "Ulcerative colitis", "Ulnar bowing", "Ulnar claw", "Ulnar deviation of finger", "Ulnar deviation of the 2nd finger", "Ulnar deviation of the hand", "Ulnar deviation of the hand or of fingers of the hand", "Ulnar deviation of the wrist", "Uncombable hair", "Unconjugated hyperbilirubinemia", "Underdeveloped nasal alae", "Underdeveloped supraorbital ridges", "Underdeveloped tragus", "Underfolded helix", "Undetectable electroretinogram", "Undetectable light and dark adapted electroretinogram", "Undetectable visual evoked potentials", "Unexplained fevers", "Unilateral cleft lip", "Unilateral cleft palate", "Unilateral primary pulmonary dysgenesis", "Unilateral ptosis", "Unilateral renal agenesis", "Unsteady gait", "Unusual fungal infection", "Unusual infection", "Unusual infection by anatomical site", "Unusual skin infection", "Upgaze palsy", "Uplifted earlobe", "Upper airway obstruction", "Upper extremity joint dislocation", "Upper eyelid coloboma", "Upper limb amyotrophy", "Upper limb asymmetry", "Upper limb hypertonia", "Upper limb muscle weakness", "Upper limb postural tremor", "Upper limb spasticity", "Upper limb undergrowth", "Upper motor neuron dysfunction", "Upslanted palpebral fissure", "Ureteral duplication", "Ureteral obstruction", "Ureteral stenosis", "Ureterocele", "Ureteropelvic junction obstruction", "Urethral obstruction", "Urethral stenosis", "Urethral stricture", "Urethral valve", "Urethrovaginal fistula", "Uric acid nephrolithiasis", "Urinary bladder sphincter dysfunction", "Urinary glycosaminoglycan excretion", "Urinary incontinence", "Urinary retention", "Urinary tract neoplasm", "Urinary urgency", "Urogenital fistula", "Urogenital sinus anomaly", "Urticaria", "Uterine prolapse", "Uterus didelphys", "Uveal melanoma", "Uveitis", "Vacuolated lymphocytes", "Vaginal atresia", "Vaginal fistula", "Vaginal neoplasm", "Variable expressivity", "Varicose veins", "Vascular calcification", "Vascular dilatation", "Vascular neoplasm", "Vascular skin abnormality", "Vascular tortuosity", "Vasculitis", "Vegetative state", "Vein of galen aneurysmal malformation", "Velopharyngeal insufficiency", "Venous insufficiency", "Venous malformation", "Venous thrombosis", "Ventilator dependence with inability to wean", "Ventricular arrhythmia", "Ventricular escape rhythm", "Ventricular fibrillation", "Ventricular hypertrophy", "Ventricular preexcitation", "Ventricular septal hypertrophy", "Ventricular tachycardia", "Ventriculomegaly", "Verrucae", "Vertebral arch anomaly", "Vertebral clefting", "Vertebral compression fracture", "Vertebral fusion", "Vertebral hypoplasia", "Vertebral segmentation defect", "Vertebral wedging", "Vertical nystagmus", "Vertical supranuclear gaze palsy", "Vertigo", "Very long chain fatty acid accumulation", "Vestibular dysfunction", "Viral encephalitis", "Viral hepatitis", "Viral infection induced rhabdomyolysis", "Visceral angiomatosis", "Visual acuity test abnormality", "Visual agnosia", "Visual field defect", "Visual fixation instability", "Visual hallucinations", "Visual impairment", "Visual loss", "Vitamin b12 deficiency", "Vitiligo", "Vitreoretinopathy", "Vitreous floaters", "Vitreous hemorrhage", "Vitritis", "Vocal cord paralysis", "Vocal cord paresis", "Volvulus", "Vomiting", "Waddling gait", "Weak cry", "Weak voice", "Weakness due to upper motor neuron dysfunction", "Weakness of facial musculature", "Weakness of long finger extensor muscles", "Weakness of muscles of respiration", "Weakness of the intrinsic hand muscles", "Webbed neck", "Weight loss", "Wheezing", "White forelock", "White hair", "Wide anterior fontanel", "Wide cranial sutures", "Wide intermamillary distance", "Wide mouth", "Wide nasal bridge", "Wide nasal ridge", "Wide nose", "Wide pubic symphysis", "Widely patent fontanelles and sutures", "Widely spaced incisors", "Widely spaced teeth", "Widened cerebral subarachnoid space", "Widened subarachnoid space", "Widow s peak", "Woolly hair", "Wormian bones", "Wrist flexion contracture", "Writer s cramp", "X linked dominant inheritance", "X linked recessive inheritance", "Xanthelasma", "Xanthomatosis", "Xerostomia", "Y shaped metacarpals", "Yellow white lesions of the retina", "Young adult onset", "Zollinger ellison syndrome", "Zonular cataract"], "available_proteins": ["AAAS", "AARS", "AARS2", "AASS", "ABAT", "ABCB1", "ABCB7", "ABCC1", "ABCD3", "ABCD4", "ABHD12", "ACACA", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACO2", "ACOX1", "ACP2", "ACSF3", "ACSL4", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ADA", "ADAM17", "ADAM9", "ADAR", "ADD1", "ADD3", "ADH5", "ADK", "ADNP", "ADPRHL2", "ADSL", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AKAP9", "AKT1", "AKT2", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALG1", "ALG11", "ALG2", "AMPD2", "ANAPC1", "ANAPC2", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANXA11", "AP1B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "APC", "APOL2", "APP", "APRT", "ARCN1", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID2", "ARL2", "ARL3", "ARL6IP1", "ARVCF", "ASAH1", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD3A", "ATIC", "ATP11C", "ATP1A1", "ATP2A2", "ATP2C1", "ATP5A1", "ATP6", "ATP6AP1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "ATPAF2", "ATRX", "ATXN10", "B4GAT1", "BANF1", "BAX", "BAZ1B", "BCAP31", "BCAT2", "BCOR", "BCS1L", "BICD2", "BLM", "BLVRA", "BMS1", "BPTF", "BRCA1", "BRD4", "BTRC", "BUB1B", "BUB3", "BUD23", "C19orf70", "C1QBP", "CAD", "CALD1", "CALM3", "CALR", "CAMK2G", "CANT1", "CAPN1", "CARS", "CARS2", "CASK", "CAST", "CBL", "CBX2", "CCDC22", "CCDC47", "CCDC8", "CCT5", "CD109", "CD2AP", "CD3EAP", "CDC40", "CDC42", "CDC45", "CDC6", "CDC73", "CDH2", "CDK13", "CDK4", "CDK5", "CDK6", "CELF2", "CEP135", "CEP250", "CEP55", "CERS1", "CFL2", "CHAMP1", "CHD1", "CHD3", "CHD4", "CHD8", "CHEK2", "CHMP1A", "CHMP2B", "CHMP4B", "CHORDC1", "CHP1", "CHST14", "CHUK", "CISD2", "CIZ1", "CLASP1", "CLCC1", "CLCN7", "CLN5", "CLPB", "CLPP", "CLPX", "CLTC", "CNNM4", "CNOT1", "CNOT2", "CNP", "COA3", "COA7", "COG7", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COQ8A", "COQ8B", "COQ9", "COX2", "COX4I1", "COX5A", "CPNE1", "CPOX", "CPSF1", "CPT1A", "CPT2", "CREB1", "CRKL", "CRTAP", "CSNK2B", "CSTB", "CTBP1", "CTCF", "CTH", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTSA", "CTSB", "CTSC", "CUL3", "CUL4B", "CUL7", "CWF19L1", "CYB5R3", "CYC1", "CYFIP2", "DARS", "DARS2", "DAXX", "DBT", "DCPS", "DCTN1", "DCTN4", "DCXR", "DDB1", "DDOST", "DDRGK1", "DDX3X", "DDX41", "DDX6", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHTKD1", "DHX16", "DHX30", "DHX37", "DHX38", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DKC1", "DLAT", "DLD", "DLG1", "DLST", "DNAAF5", "DNAJC13", "DNAJC21", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DPF2", "DPM1", "DPYSL5", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DYM", "DYNC1H1", "DYNC1I2", "DYNC2H1", "DYNLL1", "EARS2", "EBP", "ECE1", "ECHS1", "EDC3", "EEF1A2", "EEF2", "EFL1", "EFTUD2", "EGFR", "EHHADH", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF3F", "EIF4A3", "EIF4G1", "EIF4H", "EIF5A", "ELAC2", "ELMO2", "ELP1", "ELP2", "EMC1", "EMD", "EMG1", "ENPP1", "EPB41", "EPRS", "EPS15L1", "ERAL1", "ERAP1", "ERCC2", "ERCC3", "ERGIC1", "ERLIN1", "ERLIN2", "ESS2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXOC2", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC9", "EYA4", "EZH2", "EZR", "FAH", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FDFT1", "FDPS", "FDXR", "FECH", "FH", "FHL1", "FIP1L1", "FKBP10", "FKBP14", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FMR1", "FOXRED1", "FSCN1", "FTO", "FUCA1", "FUS", "FXR1", "G6PD", "GAA", "GALK1", "GALM", "GALNT2", "GANAB", "GAPVD1", "GARS", "GATAD2B", "GATB", "GATC", "GBA", "GCDH", "GDAP1", "GDI1", "GEMIN4", "GEMIN5", "GFM1", "GFPT1", "GGCX", "GIGYF2", "GLA", "GLB1", "GLDC", "GLMN", "GLRX5", "GLS", "GLT8D1", "GLUD1", "GM2A", "GMPPA", "GMPPB", "GNAI2", "GNAI3", "GNE", "GNPAT", "GNS", "GOT2", "GPAA1", "GPD2", "GPHN", "GPI", "GPKOW", "GPRASP2", "GRHPR", "GSR", "GSS", "GSTM3", "GTF2I", "GTPBP3", "GUF1", "GUSB", "GYG1", "GYS1", "H2AFY", "HADH", "HADHA", "HADHB", "HAX1", "HCCS", "HCFC1", "HELLS", "HERC2", "HEXA", "HEXB", "HEXIM1", "HIBCH", "HIRA", "HIST1H1E", "HK1", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HMBS", "HMGA1", "HMGB3", "HMGCL", "HMMR", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HOXD13", "HPRT1", "HPS3", "HPS6", "HS2ST1", "HSD17B10", "HSD17B4", "HSPA9", "HSPB1", "HSPD1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IFT27", "IFT52", "IGBP1", "IGF2BP2", "IGF2R", "IGHMBP2", "IMPAD1", "INF2", "INTS1", "IRF2BPL", "IRS4", "ISCU", "ITCH", "ITM2B", "ITPA", "IVD", "JAGN1", "JUP", "KARS", "KDM1A", "KDM3B", "KDSR", "KEAP1", "KIAA0319L", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF4A", "KIF7", "KIFBP", "KLC2", "KMT2A", "L2HGDH", "LAMB1", "LAMC1", "LAMP2", "LAMTOR2", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDHA", "LDLR", "LEMD2", "LEMD3", "LETM1", "LIPA", 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setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Cardiac muscle contraction 9 22 3.0563779183029216 0.0022402869012252 7.728155339805825 19.856796116504853 1.0644813600437804 0.240240383706381 3.4195161605095614 1.765741250102918 1.6465694074711887 0.3002212677564749 0.0175559486103657 0.1952735388158895 0.0091243340822671 9.536310572418432e-05 4.717474112626933e-05 +Endometrial cancer 2 14 2.4160802509818 0.0156886031659966 4.009708737864078 11.305825242718448 -0.0396788739446323 0.6713596098417169 2.7527396613776807 1.8808346237990337 0.7127994068913772 0.2828496750490619 0.4611241633732293 0.2145132052152406 0.3837329617110586 0.1214587331941242 0.4430646629601374 +Hypertrophic cardiomyopathy hcm 4 9 2.2742238836490887 0.0229525289428182 3.429611650485437 9.101941747572816 0.6486134300733651 0.4298239576137608 1.8675556020784376 1.719193792909202 1.0005513529453438 0.3180395638112931 0.4049686248457887 1.0 0.3339976348230559 0.0185450998789275 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0.3306587221213942 0.2005056776596591 22 Q9UDW1,P22695,P00403,P16615,O14949,P09493,P13073,P67936,P14406 9 +Endometrial cancer 0.6948774035824513 2.4160802509817993 0.0156886031659966 0.9410179401367144 0.3251968231133612 14 P31749,P31751 2 +Hypertrophic cardiomyopathy hcm 0.7652720283496478 2.2742238836490887 0.0229525289428182 0.9843359511558004 0.3251968231133612 9 P16615,P67936,P50402,P09493 4 +Colorectal cancer 0.6368261258245096 2.2353794693394673 0.0253924468000623 0.9899878041164089 0.3251968231133612 16 P31749,P31751 2 +Pancreatic cancer 0.6552100545680956 2.1885770969211986 0.0286275919881706 0.9944785696724824 0.3251968231133612 14 P31751 1 +Prostate cancer 0.60926510842845 2.153824530355366 0.0312539352182759 0.9965991984548476 0.3251968231133612 17 P31749,P49841,P31751,P16220,O15111,P62993,P27361 7 +Glioma 0.62373914917727 2.0739278045229264 0.0380860163252458 0.9990419533642712 0.3251968231133612 15 P31749,P31751 2 +Non small cell lung cancer 0.6439624707044382 2.0599784411816473 0.0394006018692245 0.9992499788253568 0.3251968231133612 13 P31751 1 +Toll like receptor signaling pathway 0.6753532490699264 2.0513427328389646 0.0402335817298642 0.9993578544577212 0.3251968231133612 11 P31751 1 +Dilated cardiomyopathy 0.7381213653933407 2.0417992908494775 0.0411714446415483 0.9994609466490236 0.3251968231133612 8 P16615,P67936,P50402,P09493 4 +Jak stat signaling pathway 0.7532490722737211 2.020187859885862 0.043363905061025 0.9996421750469632 0.3251968231133612 7 P31751 1 +Mtor signaling pathway 0.6016658696093761 2.016290875772083 0.0437695684594907 0.9996683359656268 0.3251968231133612 16 P49815,P31749,Q15418,P31751 4 +Melanoma 0.6772183473957295 1.9455771029686952 0.0517055596558886 0.9999253837214008 0.3427887103112617 10 P31751 1 +Vibrio cholerae infection 0.5272216408423833 1.9113146396547944 0.0559641588409356 0.9999666620834896 0.353398555199585 21 Q9Y487,Q93050,P24390 3 +Acute myeloid leukemia 0.6889694697453932 1.9006697453154655 0.0573452837675692 0.999974347871776 0.353398555199585 9 P31751 1 +Oxidative phosphorylation 0.4740694964100379 1.8864910887200812 0.0592288081340086 0.9999820676255876 0.353398555199585 62 P00846,O75964,Q9UDW1,Q9Y487,P22695,P00403,Q93050,P03886,P56556,O14949,O96000,P13073,O43676,Q86Y39,P14406 15 +Basal cell carcinoma 0.7224269105833409 1.7978091204807918 0.0722072615382536 0.9999985081557974 0.3939196158554459 6 O14641,P25054 2 +Fc epsilon ri signaling pathway 0.6067343230735187 1.7951986714428951 0.0726220520850822 0.9999986229146272 0.3939196158554459 12 P31751 1 +Porphyrin and chlorophyll metabolism 0.5899132383526616 1.745734772829982 0.0808570498085385 0.9999997210233644 0.4015889801460024 13 P30519,P09601,P06132 3 +Vegf signaling pathway 0.5797385300081446 1.6855056576549496 0.0918910541825261 0.9999999678860476 0.4112124674668047 13 P31749,P31751 2 +Alpha linolenic acid metabolism 0.8747978942336612 1.646518912638351 0.0996569695677962 0.9999999930970732 0.4350877451862323 3 Q15067 1 +Parkinsons disease 0.458087831681763 1.6273506696328832 0.1036626421562598 0.9999999968925936 0.4418003082373932 58 P00846,O43464,Q9UDW1,P22695,P00403,P56556,P03886,O14949,O96000,P13073,O43676,P21796,P14406,P45880 14 +Calcium signaling pathway 0.5241734646527663 1.5913524188972197 0.1115302860622096 0.9999999993587456 0.464277237328733 17 Q08209,P0DP25,P16615,P21796,P45880 5 +Primary immunodeficiency 0.8489611913087896 1.5454955123451266 0.1222264535514703 0.999999999926639 0.4858762484485974 3 P00813 1 +Thyroid cancer 0.596047554352271 1.51723182433766 0.1292081640525682 0.9999999999824342 0.4858762484485974 10 P06753,Q16204 2 +Glycerophospholipid metabolism 0.5236466078120668 1.5129559927560228 0.1302908375728082 0.999999999985941 0.4858762484485974 16 P35790,Q9HBU6,P43304,Q9HCL2 4 +Snare interactions in vesicular transport 0.5177887349419245 1.4743256670608402 0.1403939276158652 0.9999999999982636 0.5026102608647975 16 O95249,O43752,O95721,Q13277,Q13190,Q9P2W9 6 +Progesterone mediated oocyte maturation 0.4681350815246962 1.440718529220723 0.1496642179810303 0.9999999999997508 0.5133870910788005 27 P20248,P31749,P51812,P31751,Q9UJX3,P06493,Q15418,Q13257,Q9UJX4,P27361 10 +Amyotrophic lateral sclerosis als 0.5363935410135565 1.4255979225522024 0.1539844362695055 0.9999999999999 0.5133870910788005 13 P07197,P07196 2 +Proteasome 0.4625776421630623 1.4010285131310087 0.1612055468290627 0.9999999999999784 0.5242561875825469 36 P28072,P28070,O00231,Q99436,P51665,P28074,P20618,Q9UL46,P49721,P61289,Q06323 11 +Apoptosis 0.4822962469176732 1.38271635026111 0.1667518565256327 0.9999999999999934 0.5242561875825469 18 P31749,O95831,O94919,P31751 4 +B cell receptor signaling pathway 0.5246270082387219 1.354248734002799 0.1756570358202793 0.999999999999999 0.5421139553763794 13 P31749,P49841,P31751,Q08209,P62993 5 +Nicotinate and nicotinamide metabolism 0.6077469425056573 1.3326286613879397 0.1826536946517292 0.9999999999999998 0.5497346376022503 7 Q13423 1 +Small cell lung cancer 0.5232390145968552 1.3079937220716935 0.1908754386443008 1.0 0.5588388396138637 12 P31749,P31751 2 +O glycan biosynthesis 0.7000296120817227 1.3001070234238212 0.1935642908159751 1.0 0.5588388396138637 4 Q10471,Q86SF2,Q10472 3 +Biosynthesis of unsaturated fatty acids 0.5504018181043772 1.2702299032489237 0.2040027488021845 1.0 0.5675523529446477 10 Q15067 1 +Riboflavin metabolism 0.5880282265818131 1.2370970471913725 0.2160510558856923 1.0 0.5859566515687715 7 Q9NPH0 1 +Arrhythmogenic right ventricular cardiomyopathy arvc 0.4801696042739309 1.1683444308874449 0.2426678600712244 1.0 0.6295296659818721 15 P35609,P16615,P50402,P12814 4 +Melanogenesis 0.4979530309611035 1.1576633045473173 0.247001464449692 1.0 0.6316180305213555 12 O14641,Q13555,P0DP25,P16220 4 +Basal transcription factors 0.5549561236982831 1.0766302426483516 0.2816454877264807 1.0 0.7046001415844229 7 P35269,P29083,Q15545,O00268 4 +Tight junction 0.4139987276673181 1.0207283992656937 0.3073831355950887 1.0 0.729327326490241 44 P35609,Q13813,Q96A65,P31749,P31751,P30154,P35580,P35579,O43707,P12814,Q8N3R9 11 +Dorso ventral axis formation 0.5887680290329556 1.0121515006117792 0.311465621318977 1.0 0.729327326490241 5 P62993,P00533,P27361 3 +Viral myocarditis 0.498500053941913 0.9872748615161016 0.3235079108735057 1.0 0.729327326490241 10 P35579,P35580 2 +P53 signaling pathway 0.4587523435822915 0.9867677114027852 0.3237565270328568 1.0 0.729327326490241 14 P31350,O14681,P06493,Q9Y3B8,P49815,Q07812,P11802 7 +Alzheimers disease 0.3763317045370029 0.974051837681112 0.3300308013726789 1.0 0.729327326490241 66 P00846,Q08209,Q9UDW1,P22695,P00403,P56556,P0DP25,P16615,O14949,O96000,P13073,O43676,P14406 13 +T cell receptor signaling pathway 0.4041404005617409 0.9518072986241498 0.3411947198471128 1.0 0.7448031079589413 23 Q12959,Q08209,P31749,P31751,P49841,O15111,P62993,P27361,P11802 9 +Huntingtons disease 0.3267421697008008 0.8774798297701891 0.3802260697494473 1.0 0.7896461761092732 81 P00846,Q9UDW1,P22695,P00403,P56556,O14949,O96000,P42858,P13073,O43676,P21796,P14406,P16220,P45880 14 +Chronic myeloid leukemia 0.4108632366908293 0.8715183383466187 0.3834711973241127 1.0 0.7896461761092732 18 P31751 1 +Adipocytokine signaling pathway 0.424337417217095 0.8514049186181734 0.3945444604150363 1.0 0.7896461761092732 16 Q9UKU0,P31751 2 +Erbb signaling pathway 0.3876548407857287 0.8469395728064975 0.3970288036303608 1.0 0.7896461761092732 20 P31751 1 +Tgf beta signaling pathway 0.4547616485326123 0.7513524678522943 0.45244056059351 1.0 0.8436131286066489 10 P30154,O75116,P27361,P63208,P30153 5 +Renin angiotensin system 0.5517744057831984 0.6933549361837793 0.488086835119379 1.0 0.9006963246017405 4 Q9BYT8,P52888 2 +Sphingolipid metabolism 0.4121221220903562 0.6707815287728701 0.5023597161651343 1.0 0.9083069615511014 13 Q16739,Q06136 2 +N glycan biosynthesis 0.3691145872018044 0.6363164262460435 0.5245702006623456 1.0 0.916536153687582 19 Q2TAA5,O60476,Q9BT22,P33908,Q86YN1 5 +Ascorbate and aldarate metabolism 0.469105956064491 0.6300213942701475 0.528680586783119 1.0 0.916536153687582 6 P51648 1 +Neurotrophin signaling pathway 0.3678488854210929 0.6146562864687563 0.53878173412702 1.0 0.916536153687582 33 P31749,P51812,P49841,P31751,Q13555,P0DP25,Q15418,O14654,P62993 9 +Epithelial cell signaling in helicobacter pylori infection 0.3611187853494981 0.6035411349354178 0.5461487591938345 1.0 0.916536153687582 25 Q93050 1 +Glycerolipid metabolism 0.415083358776658 0.6009495834175316 0.5478735667294485 1.0 0.916536153687582 11 P51648,Q9HCL2 2 +Bladder cancer 0.4604444444444476 0.5923199579087486 0.5536363538584417 1.0 0.9176009938950098 6 P00533,P11802,P28482,P27361,Q02750 5 +Antigen processing and presentation 0.3522709990383599 0.5790931716243548 0.5625263072429463 1.0 0.9183276001167916 20 P61289,Q06323,P16220,Q03518 4 +Histidine metabolism 0.4479246344933544 0.5713850829533533 0.5677386385236574 1.0 0.9183276001167916 7 P51648 1 +Olfactory transduction 0.5759802517026213 0.5143606744825836 0.6069998483253558 1.0 0.959927684979138 3 P0DP25 1 +Adherens junction 0.338378326398085 0.4191945683720127 0.6750739413825562 1.0 0.9700185337015658 27 P12814,Q9UQB8,P35609,P10586 4 +Phosphatidylinositol signaling system 0.3876942663669266 0.4099260606336192 0.6818601875741801 1.0 0.9700185337015658 10 P0DP25,Q8TBX8 2 +Retinol metabolism 0.441428680955179 0.4067552155626917 0.6841877822262226 1.0 0.9700185337015658 5 O94788 1 +Renal cell carcinoma 0.3384434386985949 0.3766691801471233 0.7064194693873436 1.0 0.9700185337015658 18 P31751 1 +Aldosterone regulated sodium reabsorption 0.394740699457341 0.3719879354921319 0.7099018319268442 1.0 0.9700185337015658 8 Q9Y3B8,O14654,P05023,P05026 4 +Butanoate metabolism 0.3162516215919782 0.3139847308699575 0.7535326357623939 1.0 0.9796821809704276 21 Q9BWD1,P51648 2 +Tryptophan metabolism 0.3380847179098444 0.3100947015472133 0.7564889413649911 1.0 0.9796821809704276 16 Q9BWD1,P51648 2 +Chemokine signaling pathway 0.3166393618142654 0.2812090864069061 0.778550035811002 1.0 0.9796821809704276 25 P31751 1 +Wnt signaling pathway 0.3119126571826984 0.2198883253330922 0.8259581288419153 1.0 0.9869617032488448 29 Q08209,P30154,P25054,Q13555,O14641,O75116,Q9Y297 7 +Cysteine and methionine metabolism 0.323815987888364 0.2140431854468474 0.8305133803661833 1.0 0.9869617032488448 15 Q13126,Q9BV57,O43865,Q99707 4 +Peroxisome 0.3171914313792659 0.2113981088113369 0.8325766323495842 1.0 0.9869617032488448 38 O75381,Q9NR77,Q15067,Q13011,O15254,Q9UKU0 6 +Mapk signaling pathway 0.3161324010980633 0.1963418329449465 0.8443426205941931 1.0 0.9943245334628984 41 P16949,P31749,Q9Y4G8,P31751,Q9H2K8,Q15418 6 +Gnrh signaling pathway 0.3065907060196953 0.1172381124733766 0.9066713657667484 1.0 1.0 12 P62993,Q13555,P27361,P0DP25 4 +Hedgehog signaling pathway 0.3232698887397032 0.1071306574393209 0.9146853259986976 1.0 1.0 6 Q9Y297,P49841 2 +Ppar signaling pathway 0.2816515127863168 0.1009148491046528 0.9196180554038362 1.0 1.0 21 Q15067,Q9UKU0 2 +Cell adhesion molecules cams 0.2997004245927024 0.0902682431098501 0.928074055425939 1.0 1.0 13 Q16625,Q92896,P10586 3 +Pathways in cancer 0.2998231494781253 0.0884536687012602 0.9295161069592796 1.0 1.0 55 P06753,P31749,P31751,P25054,O14641,Q16204 6 +Notch signaling pathway 0.303973902728349 0.0643264657615858 0.9487102804600712 1.0 1.0 9 Q13573,Q92542,P56545,P78536,Q06330,O14641,Q13547,Q92769 8 +Leukocyte transendothelial migration 0.2779333365369105 0.0543587328226837 0.956649356652401 1.0 1.0 24 P35609,P15311,O43707,O75116,P12814 5 +Protein export 0.2745072277958296 0.0057046944301148 0.9954483370779964 1.0 1.0 16 P67812 1 +Lysine degradation 0.2728657528152165 0.0044738797636064 0.996430372317774 1.0 1.0 27 Q9BWD1,P30837,P51648,Q8WTS6 4 diff --git a/msigdb_kegg/selections.json b/msigdb_kegg/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..fbfe1a1b2e1873a38bf9c2a58be4ac3a59f58d04 --- /dev/null +++ b/msigdb_kegg/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Abc transporters", "Acute myeloid leukemia", "Adherens junction", "Adipocytokine signaling pathway", "Alanine aspartate and glutamate metabolism", "Aldosterone regulated sodium reabsorption", "Allograft rejection", "Alpha linolenic acid metabolism", "Alzheimers disease", "Amino sugar and nucleotide sugar metabolism", "Aminoacyl trna biosynthesis", "Amyotrophic lateral sclerosis als", "Antigen processing and presentation", "Apoptosis", "Arachidonic acid metabolism", "Arginine and proline metabolism", "Arrhythmogenic right ventricular cardiomyopathy arvc", "Ascorbate and aldarate metabolism", "Autoimmune thyroid disease", "Axon guidance", "B cell receptor signaling pathway", "Basal cell carcinoma", "Basal transcription factors", "Base excision repair", "Beta alanine metabolism", "Biosynthesis of unsaturated fatty acids", "Bladder cancer", "Butanoate metabolism", "Calcium signaling pathway", "Cardiac muscle contraction", "Cell adhesion molecules cams", "Cell cycle", "Chemokine signaling pathway", "Chronic myeloid leukemia", "Citrate cycle tca cycle", "Colorectal cancer", "Cysteine and methionine metabolism", "Cytokine cytokine receptor interaction", "Cytosolic dna sensing pathway", "Dilated cardiomyopathy", "Dna replication", "Dorso ventral axis formation", "Drug metabolism cytochrome p450", "Drug metabolism other enzymes", "Ecm receptor interaction", "Endocytosis", "Endometrial cancer", "Epithelial cell signaling in helicobacter pylori infection", "Erbb signaling pathway", "Ether lipid metabolism", "Fatty acid metabolism", "Fc epsilon ri signaling pathway", "Fc gamma r mediated phagocytosis", "Focal adhesion", "Folate biosynthesis", "Fructose and mannose metabolism", "Galactose metabolism", "Gap junction", "Glioma", "Glutathione metabolism", "Glycerolipid metabolism", "Glycerophospholipid metabolism", "Glycine serine and threonine metabolism", "Glycolysis gluconeogenesis", "Glycosaminoglycan biosynthesis chondroitin sulfate", "Glycosaminoglycan biosynthesis heparan sulfate", "Glycosaminoglycan biosynthesis keratan sulfate", "Glycosaminoglycan degradation", "Glycosphingolipid biosynthesis ganglio series", "Glycosphingolipid biosynthesis globo series", "Glycosphingolipid biosynthesis lacto and neolacto series", "Glycosylphosphatidylinositol gpi anchor biosynthesis", "Glyoxylate and dicarboxylate metabolism", "Gnrh signaling pathway", "Graft versus host disease", "Hedgehog signaling pathway", "Hematopoietic cell lineage", "Histidine metabolism", "Homologous recombination", "Huntingtons disease", "Hypertrophic cardiomyopathy hcm", "Inositol phosphate metabolism", "Insulin signaling pathway", "Jak stat signaling pathway", "Leishmania infection", "Leukocyte transendothelial migration", "Limonene and pinene degradation", "Long term depression", "Long term potentiation", "Lysine degradation", "Lysosome", "Mapk signaling pathway", "Melanogenesis", "Melanoma", "Metabolism of xenobiotics by cytochrome p450", "Mismatch repair", "Mtor signaling pathway", "N glycan biosynthesis", "Natural killer cell mediated cytotoxicity", "Neuroactive ligand receptor interaction", "Neurotrophin signaling pathway", "Nicotinate and nicotinamide metabolism", "Nitrogen metabolism", "Nod like receptor signaling pathway", "Non homologous end joining", "Non small cell lung cancer", "Notch signaling pathway", "Nucleotide excision repair", "O glycan biosynthesis", "Olfactory transduction", "One carbon pool by folate", "Oocyte meiosis", "Other glycan degradation", "Oxidative phosphorylation", "P53 signaling pathway", "Pancreatic cancer", "Pantothenate and coa biosynthesis", "Parkinsons disease", "Pathogenic escherichia coli infection", "Pathways in cancer", "Pentose and glucuronate interconversions", "Pentose phosphate pathway", "Peroxisome", "Phenylalanine metabolism", "Phosphatidylinositol signaling system", "Porphyrin and chlorophyll metabolism", "Ppar signaling pathway", "Primary bile acid biosynthesis", "Primary immunodeficiency", "Prion diseases", "Progesterone mediated oocyte maturation", "Propanoate metabolism", "Prostate cancer", "Proteasome", "Protein export", "Proximal tubule bicarbonate reclamation", "Purine metabolism", "Pyrimidine metabolism", "Pyruvate metabolism", "Regulation of actin cytoskeleton", "Regulation of autophagy", "Renal cell carcinoma", "Renin angiotensin system", "Retinol metabolism", "Riboflavin metabolism", "Ribosome", "Rig i like receptor signaling pathway", "Rna degradation", "Rna polymerase", "Selenoamino acid metabolism", "Small cell lung cancer", "Snare interactions in vesicular transport", "Sphingolipid metabolism", "Spliceosome", "Starch and sucrose metabolism", "Steroid biosynthesis", "Steroid hormone biosynthesis", "Sulfur metabolism", "Systemic lupus erythematosus", "T cell receptor signaling pathway", "Taste transduction", "Terpenoid backbone biosynthesis", "Tgf beta signaling pathway", "Thyroid cancer", "Tight junction", "Toll like receptor signaling pathway", "Tryptophan metabolism", "Type i diabetes mellitus", "Type ii diabetes mellitus", "Tyrosine metabolism", "Ubiquitin mediated proteolysis", "Valine leucine and isoleucine biosynthesis", "Valine leucine and isoleucine degradation", "Vascular smooth muscle contraction", "Vasopressin regulated water reabsorption", "Vegf signaling pathway", "Vibrio cholerae infection", "Viral myocarditis", "Wnt signaling pathway"], "available_proteins": ["AACS", "AARS", "AARS2", "AASDHPPT", "AASS", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTN1", "ACTN2", "ACTN4", "ADA", "ADAM17", "ADAR", "ADH5", "ADI1", "ADK", "ADSL", "ADSS", "AFDN", "AGK", "AGL", "AGPS", "AHCY", "AHCYL1", "AIFM1", "AK1", "AK2", "AK3", "AK4", "AKR1A1", "AKR1B1", "AKT1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG2", "ALG5", "ALYREF", "AMPD2", "ANAPC1", "ANAPC2", "ANAPC5", "ANAPC7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APBB1", "APC", "APEX1", "APP", "APRT", "AQR", "ARF6", "ARFGAP1", "ARFGAP2", "ARG2", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASNA1", "ASNS", "ATG4B", "ATIC", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATRX", "B4GAT1", "BAIAP2", "BAX", "BCAS2", "BCAT2", "BDH2", "BIRC6", 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"CUL3", "CUL4B", "CUL5", "CUL7", "CWC15", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DARS", "DARS2", "DAXX", "DBT", "DCP1A", "DCP2", "DCPS", "DCTN1", "DCTN2", "DCTN4", "DCXR", "DDB1", "DDOST", "DDX23", "DDX39B", "DDX3X", "DDX42", "DDX46", "DDX5", "DDX6", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHRS4", "DHX15", "DHX16", "DHX38", "DHX8", "DIAPH1", "DIAPH3", "DIS3", "DLAT", "DLD", "DLG1", "DLST", "DNM1L", "DNM2", "DNMT1", "DOLPP1", "DPM1", "DPYSL2", "DPYSL5", "DSC2", "DSG2", "DSP", "DTYMK", "DUSP3", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBP", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EEA1", "EFTUD2", "EGFR", "EHD1", "EHD4", "EHHADH", "EHMT2", "EI24", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "ELOB", "ELOC", "EMD", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENPP1", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPN1", "EPRS", "EPS15", "ERBIN", "ERCC2", "ERCC3", "ERO1A", "ESPL1", 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0.237888308904226 0.1006582454154426 0.191600110602388 0.0990342687178565 0.2914565107291916 +Interleukin 4 and interleukin 13 signaling 2 12 2.026736839781316 0.0426893327937343 2.5558252427184467 12.196601941747574 0.5560470992805083 0.4901493467828993 1.7856738546249034 0.6774367070325202 0.8330053405728306 0.3000407147159935 0.0860413107114576 1.0 0.0563311776114605 0.072741111398958 0.3092787829323835 +Sensory processing of sound by outer hair cells of the cochlea 7 14 2.0133528680298234 0.0440775202209111 5.344660194174757 12.723300970873789 -0.1102522522144516 0.6398584593428776 3.3052834478966804 1.4914451116507836 0.78467998862094 0.2966859344433833 1.0 1.0 1.0 1.0 0.1199524552735497 +Slc mediated transmembrane transport 7 23 2.00835519716347 0.0446055602537984 8.672330097087379 21.910194174757283 1.4735742044813558 0.239038892478899 4.348519601656105 3.146764860695784 1.3934177975338422 0.3068823132077037 0.3520747233515442 0.3867386931517215 0.6248041208228576 0.4470347519884879 0.2219073979752139 +Heme signaling 3 6 1.9734883297897572 0.0484399528749668 1.230582524271845 5.803398058252427 0.6243516489333526 0.4389875136545328 1.4355867683297088 1.6714879444213002 0.8385522152075133 0.2749710688420202 0.3590770211139655 1.0 0.2941077913158182 0.5885248237912099 0.2554523730097116 +Ras activation upon ca2 influx through nmda receptor 3 6 1.972137324945632 0.0485939320805965 1.6213592233009708 4.587378640776699 0.5142991639310069 0.4720716967840462 1.1854007134893856 1.2364354977621388 0.9803951431106008 0.3190011025936756 0.1482449280840973 1.0 1.0 0.2740704871267072 0.0228394808772788 +Unblocking of nmda receptors glutamate binding and activation 3 6 1.972137324945632 0.0485939320805965 1.587378640776699 4.512135922330097 0.5222988846235571 0.4713678555882069 1.1552480178925886 1.1976304683860852 0.9824422295410165 0.3195479952048319 0.1051177798435183 1.0 1.0 0.1988473022417859 0.0077568745967145 +Long term potentiation 3 6 1.972137324945632 0.0485939320805965 1.6407766990291262 4.66747572815534 0.5172028383345088 0.4739563925990347 1.1770818692154363 1.2340675647083696 0.9625233470081714 0.3154279586014728 0.1269454833803885 1.0 1.0 0.2373820829012167 0.0141665154869097 +G protein beta gamma signalling 1 7 1.969711139687784 0.0488714855619332 1.7718446601941749 5.211165048543689 0.0136852380664441 0.5590401988123619 1.246892640696441 1.573929471884848 0.9420889570977656 0.3179818542906523 0.237888308904226 0.1006582454154426 0.191600110602388 0.0990342687178565 0.2914565107291916 +Assembly and cell surface presentation of nmda receptors 7 12 1.962437741851513 0.0497115423121199 4.021844660194175 10.050970873786408 0.6119431771279947 0.4638365400303644 2.466672711798564 1.7830986526204615 1.029606868598912 0.3372268056856337 0.2923845056635012 1.0 1.0 0.4986229205358068 0.1539585868211262 diff --git a/msigdb_reactome/metrics.json b/msigdb_reactome/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..a35f45a8d834521034ca5e9b8686309a262a0935 --- /dev/null +++ b/msigdb_reactome/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3381, + "annotations_size": 1396, + "title": "Average number of proteins per term", + "value": 20.249283667621775 +} \ No newline at end of file diff --git a/msigdb_reactome/paths.json b/msigdb_reactome/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..76e8360c2cfacbc1a7a7f13b83c46211a31743bf --- /dev/null +++ b/msigdb_reactome/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_reactome/fragment/C317/C317_val_log2fc"} \ No newline at end of file diff --git a/msigdb_reactome/result.tsv b/msigdb_reactome/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..652fa048b8e006a0b677388d5b8191e7869950a7 --- /dev/null +++ b/msigdb_reactome/result.tsv @@ -0,0 +1,492 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Protein localization 0.5334615555778841 3.3810821334443983 0.0007220095774487 0.6351574583593833 0.4028754143306906 81 P40855,O60830,O60220,Q9Y5J7,Q13505,P46379,Q9Y5J9,Q9NS69,O43681,O43808,Q99595,Q13190,P51648,O75381,O14925,Q8N4H5,Q9NR77,Q13011,P06576,P21796,P09601,Q9NX63,O15254,Q15067,Q5JRX3,O00116,P49069,P50402 28 +Intra golgi traffic 0.7019687318838785 2.627865448440903 0.008592249414858 0.9999941355880698 0.7066242001507785 16 O95249,O00461,O43752,O60476,O95721,Q8TBA6,P33908 7 +Class i peroxisomal membrane protein import 0.7498156245439731 2.4398414397092663 0.014693709697864 0.9999999989395932 0.7066242001507785 11 O75381,P40855,Q9NR77,Q8TB36,O43808,P51648 6 +Striated muscle contraction 0.8445348964273665 2.4290538455129553 0.0151382838845055 0.999999999435249 0.7066242001507785 7 P35609,P67936,P08670,P09493 4 +Mitochondrial protein import 0.5864359108757116 2.398219064215527 0.0164750089614758 0.9999999999151956 0.7066242001507785 36 O14925,O60220,O60830,Q8N4H5,Q9Y5J7,Q13505,Q9Y5J9,Q5JRX3,Q9NS69,Q99595,Q9NX63,P21796 12 +Activation of bad and translocation to mitochondria 0.7845722328688106 2.3662899312666656 0.0179673675650702 0.9999999999898193 0.7066242001507785 9 P31751 1 +Iron uptake and transport 0.6177954284233333 2.312319213154939 0.020760098656827 0.9999999999998088 0.7066242001507785 18 P30519,P09601,Q93050 3 +Regulation of localization of foxo transcription factors 0.8173741735426064 2.3093838610064847 0.0209222897941507 0.9999999999998485 0.7066242001507785 7 P31751 1 +Mitotic g2 g2 m phases 0.4026459042477294 2.3033022032707793 0.0212618457678717 0.9999999999999066 0.7066242001507785 96 P28072,Q9BV73,P28074,P20618,O94927,Q14997,Q9Y297,P61289,P41208,Q9BSJ2,P28070,P30154,O75935,Q9H6D7,Q06323,Q66GS9,P51665,O95684,Q9UL46,O43805,Q99996,P49721,O00231,Q99436 24 +Synthesis of pa 0.813056495507533 2.2902051724879433 0.022009425732707 0.9999999999999678 0.7066242001507785 7 Q8N2A8,Q9NPH0,Q9HCL2 3 +Organelle biogenesis and maintenance 0.4032269476031583 2.274203213213857 0.0229537711495808 0.9999999999999916 0.7066242001507785 100 Q13505,Q9BV73,O94927,Q10713,P41208,P00846,Q13561,O75964,O75935,P06576,Q86X55,Q9H6D7,A6NIH7,Q15648,Q66GS9,P78371,O95684,Q9NX63,O43805,Q99996,P24539,P16220,Q8NCM8,Q92973,Q7Z4L5,Q96A65,P17152,A0AVF1,P49368 29 +Transport of inorganic cations anions and amino acids oligopeptides 0.716722460759441 2.2693047128147916 0.0232498021468705 0.9999999999999946 0.7066242001507785 11 Q70HW3,Q96QD8,Q9Y6M7,P30825,Q9UBX3 5 +Estrogen dependent nuclear events downstream of esr membrane signaling 0.8052138099500395 2.2552599039497734 0.0241170198124811 0.9999999999999984 0.7066242001507785 7 P31751,P31749 2 +Cristae formation 0.5735088174685441 2.2519632642834377 0.0243245935948226 0.9999999999999988 0.7066242001507785 20 P00846,O75964,Q13505,P17152,Q9NX63,P06576 6 +Sphingolipid de novo biosynthesis 0.7372869049208401 2.25120256276706 0.0243727106644775 0.9999999999999988 0.7066242001507785 10 O95470,Q06136,Q96G23 3 +Pink1 prkn mediated mitophagy 0.7816781693605699 2.245921501153773 0.0247090364111797 0.9999999999999992 0.7066242001507785 8 Q9NS69,P21796,Q8IWA4,Q8N4H5 4 +Ire1alpha activates chaperones 0.5657647889056536 2.191909952849204 0.0283860092761971 1.0 0.7066242001507785 26 Q9Y5M8,O43731,P51858,Q9NWM8,P43307 5 +Muscle contraction 0.5613975581472073 2.160799859386539 0.0307108029487772 1.0 0.7066242001507785 27 P35609,P06753,P05023,O43865,Q13555,P08670,P16615,Q99996,P09493,P67936 10 +Intra golgi and retrograde golgi to er traffic 0.3954119259666943 2.139613774450164 0.0323859925056411 1.0 0.7066242001507785 103 Q9H0B6,Q13439,Q8TBA6,Q13190,Q12981,P24390,O95249,O00461,P33176,O43752,O60333,O60476,O95721,Q8TD16,Q15363,O75935,P33908,P53365,O43731,Q9P2W9,P49755,Q10472,Q9UID3,O15260 24 +Heme degradation 0.9029009355293308 2.128355999758671 0.033307578338714 1.0 0.7066242001507785 4 P30519 1 +Mitophagy 0.6885917611757961 2.121668648071301 0.0338655731833197 1.0 0.7066242001507785 11 Q9NS69,P21796,Q8IWA4,Q8N4H5 4 +Creb1 phosphorylation through nmda receptor mediated activation of ras signaling 0.6872193849274267 2.114403376489897 0.0344808295253045 1.0 0.7066242001507785 11 P35609,P07196,P51812,Q13555,P16220,Q15418,P27361,Q14168 8 +Cd28 dependent pi3k akt signaling 0.8938516057423345 2.0925653066659216 0.036387976274657 1.0 0.7066242001507785 4 P31751 1 +Mitochondrial calcium ion transport 0.6130240355580209 2.0876182436100352 0.0368322849899191 1.0 0.7066242001507785 16 Q9BPX6,Q9Y4W6,Q8IYU8,Q10713,Q9NWR8,P21796,P45880 7 +Cytoprotection by hmox1 0.4759051318079887 2.0650490058481297 0.0389183636764629 1.0 0.7066242001507785 67 P28072,P30519,Q8N8Q8,P28074,P20618,P42704,Q14997,P61289,P28070,Q8TCT9,Q86X55,Q06323,P09601,P51665,P00403,Q9UL46,P13073,P49721,O75880,O00231,Q99436 21 +Signaling by insulin receptor 0.5924211362202028 2.0448700623116025 0.0408676701280568 1.0 0.7066242001507785 17 Q93050,P31751 2 +G beta gamma signalling through pi3kgamma 0.8264737305860534 2.044066898093297 0.0409469387409808 1.0 0.7066242001507785 5 P31751 1 +Vegfr2 mediated vascular permeability 0.6494656897620683 2.0366734602085206 0.0416827758177631 1.0 0.7066242001507785 12 P31751 1 +Interleukin 4 and interleukin 13 signaling 0.6476861129880791 2.0267368397813157 0.0426893327937343 1.0 0.7066242001507785 12 P08670,P09601 2 +Sensory processing of sound by outer hair cells of the cochlea 0.6253288546403891 2.0133528680298234 0.0440775202209111 1.0 0.7066242001507785 14 Q13813,O00159,O14936,P35579,P15311,Q00013,Q01082 7 +Slc mediated transmembrane transport 0.5409460960003839 2.00835519716347 0.0446055602537984 1.0 0.7066242001507785 23 Q70HW3,Q8TB61,Q96QD8,Q9Y6M7,P30825,Q9UBX3,Q8NEW0 7 +Heme signaling 0.7615720943266896 1.9734883297897576 0.0484399528749668 1.0 0.7066242001507785 6 P09601,P16220,Q86X55 3 +Ras activation upon ca2 influx through nmda receptor 0.7612684397764197 1.972137324945632 0.0485939320805965 1.0 0.7066242001507785 6 P35609,P07196,Q14168 3 +Unblocking of nmda receptors glutamate binding and activation 0.7612684397764197 1.972137324945632 0.0485939320805965 1.0 0.7066242001507785 6 P35609,P07196,Q14168 3 +Long term potentiation 0.7612684397764197 1.972137324945632 0.0485939320805965 1.0 0.7066242001507785 6 P35609,P07196,Q14168 3 +G protein beta gamma signalling 0.7422620755657594 1.969711139687784 0.0488714855619332 1.0 0.7066242001507785 7 P31751 1 +Assembly and cell surface presentation of nmda receptors 0.6362159215887846 1.962437741851513 0.0497115423121199 1.0 0.7066242001507785 12 P35609,P68371,P07196,Q13555,O14936,Q9BUF5,Q14168 7 +Regulation of beta cell development 0.8555098984164 1.9395236412253285 0.0524376086798694 1.0 0.7066242001507785 4 P31751 1 +Flt3 signaling 0.7535578301328535 1.9377689106642495 0.0526514223439844 1.0 0.7066242001507785 6 P31751 1 +Downregulation of erbb2 signaling 0.7161202204206395 1.936957296101188 0.052750563670942 1.0 0.7066242001507785 8 P31751 1 +Pre notch processing in golgi 0.854334609745705 1.9347976260506068 0.0530151345380081 1.0 0.7066242001507785 4 Q9UBV2,P16615 2 +Recruitment of mitotic centrosome proteins and complexes 0.5255968614063415 1.91903096278273 0.0549804154439517 1.0 0.7066242001507785 36 Q13561,Q13409,Q14203,Q9BV73,Q66GS9,Q15154,P06493,O95684,O75935,O43805,Q99996,O94927,Q9H6D7,P21127,Q9BSJ2,P41208 16 +Intrinsic pathway for apoptosis 0.5274233656893771 1.916473937451836 0.0553047975072014 1.0 0.7066242001507785 20 Q9NR28,P31751 2 +Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.6245983271763303 1.8968700607825784 0.0578450897394529 1.0 0.7066242001507785 12 P09601,P46379,O43681,P49069,P50402,Q13190,P51648 7 +Constitutive signaling by akt1 e17k in cancer 0.6872256118235858 1.8919573134888927 0.0584966684713057 1.0 0.7066242001507785 9 P31749,P16220,P31751 3 +Apoptosis 0.3665312975603931 1.8689952288198572 0.0616234781805509 1.0 0.7066242001507785 89 P28072,Q13813,P31751,P28074,O60313,P20618,P61289,P28070,P31749,O00429,Q06323,P25054,P08670,Q9NR28,P51665,Q9UL46,P49721,P35611,O00231,Q99436,P09429 21 +Disassembly of the destruction complex and recruitment of axin to the membrane 0.7013058062706845 1.8657237241099216 0.0620800287011102 1.0 0.7066242001507785 8 O14641,P25054 2 +Deactivation of the beta catenin transactivating complex 0.615253647187422 1.8438124261727928 0.0652104811438105 1.0 0.7224907275933297 12 P31749,P31751 2 +Egr2 and sox10 mediated initiation of schwann cell myelination 0.7139126790122399 1.8382592000362368 0.0660242200892642 1.0 0.7257465452331722 7 Q16850 1 +Metabolism of porphyrins 0.6752993142819 1.8321712362910505 0.0669259128122869 1.0 0.7270184710224001 9 P30519,P09601,P06132 3 +Anchoring of the basal body to the plasma membrane 0.5146977112035883 1.8204803799941205 0.0686858814541131 1.0 0.7270184710224001 34 Q13561,Q13409,Q15019,Q14203,Q9BV73,Q66GS9,Q15154,P06493,O95684,O75935,O43805,Q99996,O94927,Q9H6D7,P41208 15 +Mapk family signaling cascades 0.3637629881698895 1.8103842928760177 0.0702362133717955 1.0 0.7296759840698405 91 P28072,Q13813,Q9Y4G8,Q96P70,P28074,P20618,O60725,P61289,P28070,P30154,Q06323,Q01082,P51665,Q9UL46,P49721,P35609,P07196,O00231,Q99436,O15020,Q14168 21 +Ion transport by p type atpases 0.63008773080593 1.80687440085598 0.0707818647707767 1.0 0.7296759840698405 11 P16615,Q9HD20,P98194,P05023 4 +Mtor signalling 0.5269463854387276 1.7978161582184728 0.0722061458959784 1.0 0.7357648151152252 19 P49815,P31749,P62942,P31751 4 +Negative regulation of nmda receptor mediated neuronal transmission 0.6846309048657894 1.7849487805348034 0.0742696252351859 1.0 0.7414424844026472 8 P35609,P07196,Q14168 3 +Signaling by interleukins 0.3736674881262218 1.7719985920505834 0.0763947909397406 1.0 0.7414424844026472 110 P28072,P28074,P20618,O00170,Q14997,Q9Y297,P61289,P28070,Q9H3S7,P31749,P30154,P78417,Q13277,O14979,Q06323,Q13501,P09601,Q13126,P51665,P08670,Q9UL46,P16220,P49721,P14174,O00231,Q99436,P52597,P09429,Q15418 29 +Ion channel transport 0.5101145021549599 1.77197778118125 0.0763982455615692 1.0 0.7414424844026472 30 Q9C0H2,P05023,Q9Y487,Q13555,Q9Y5K8,Q93050,P16615,Q9HD20,P98194 9 +Sema4d induced cell migration and growth cone collapse 0.6996478831507181 1.7714784499315337 0.0764811731762042 1.0 0.7414424844026472 7 P35579,P35580,O75116,Q7Z406 4 +Regulation of pten stability and activity 0.5000138442117337 1.7662551162408686 0.0773530580017705 1.0 0.7447232342791146 43 P28072,P28070,O00231,P31751,P31749,Q99436,P51665,P28074,P20618,Q9UL46,P49721,P61289,Q06323 13 +Gamma carboxylation hypusine formation and arylsulfatase activation 0.6200779652603967 1.7520054412236556 0.0797728722974373 1.0 0.7474022129343795 11 O60725,Q9BU89 2 +Akt phosphorylates targets in the nucleus 0.8990526939017066 1.7409064541760924 0.0816999772046178 1.0 0.7528639299282264 3 P31749,P31751 2 +Signaling by ptk6 0.5888315562611997 1.7393471237450908 0.0819737230294344 1.0 0.7528639299282264 13 O75525,P31749,Q07666,P23246,Q8IZL8 5 +Processing of smdt1 0.6139148999447759 1.718083571277984 0.0857813729712342 1.0 0.7615201340140082 11 Q9Y4W6,Q9NWR8,Q8IYU8,Q9BPX6 4 +Nuclear signaling by erbb4 0.8006034515024696 1.7166805997878647 0.0860375467282588 1.0 0.7615201340140082 4 P16949 1 +Ctla4 inhibitory signaling 0.6674497385516837 1.7010883610772052 0.0889263961170645 1.0 0.7615201340140082 8 P31749,P31751 2 +Regulation of tp53 expression and degradation 0.5797794132563266 1.6857483053833164 0.0918442884742363 1.0 0.7615201340140082 13 P31749,P31751 2 +Cilium assembly 0.4416934863863332 1.6749127029168351 0.0939513608906008 1.0 0.7615201340140082 66 Q13409,Q9BV73,P50991,Q15154,O94927,Q10713,P41208,Q13561,Q15019,O75935,Q9H6D7,A6NIH7,Q14203,Q66GS9,P78371,O95684,O43805,Q99996,Q8NCM8,Q92973,Q7Z4L5,Q8TAG9,Q96A65,A0AVF1,P06493,P49368 26 +Antigen processing ubiquitination proteasome degradation 0.3564871285319095 1.6680858727670729 0.0952986811884541 1.0 0.7615201340140082 95 P28072,P28074,P20618,Q14997,P61289,Q9Y297,Q9Y508,P28070,Q7Z7E8,P55786,Q06323,Q92990,P51665,Q05086,Q9UL46,P52888,P49721,O00231,Q9UBS8,Q99436,Q9UJX4 21 +S phase 0.358808333194018 1.6631052718747614 0.0962913648052232 1.0 0.7615201340140082 99 P28072,P20248,P31751,Q14566,P28074,P20618,Q92530,Q9Y2S7,Q14997,P61289,Q9UQE7,Q13200,Q13416,P11802,P28070,P25787,P31749,Q9UJX3,Q9NR33,Q96DE5,Q9BRT9,P40937,Q06323,Q9Y619,P49841,O75419,P33993,P51665,O43242,Q9UL46,P17980,P24941,O00487,P49721,P33991,O00231,Q29RF7,P25205,Q99436,Q9UBD5,Q9UNM6,Q9UJX4,P62191,P63208 44 +Akt phosphorylates targets in the cytosol 0.6921723979575036 1.660045939979296 0.0969052110144681 1.0 0.7615201340140082 6 P31751,P31749 2 +Cholesterol biosynthesis 0.5342900553202408 1.659720714311158 0.0969706502251226 1.0 0.7615201340140082 17 P48449,Q16850,Q15125,Q9BWD1,Q15800,Q15392,Q14739 7 +Apoptotic factor mediated response 0.6917068293804569 1.6579134476165749 0.0973349374737821 1.0 0.7615201340140082 6 Q9BZF9,Q07812,Q9NR28,Q07021 4 +Phase i functionalization of compounds 0.5657385445248141 1.6544046011935871 0.0980453322173586 1.0 0.7615201340140082 14 P30837,Q16850,P07099,O43169,P16435 5 +Aurka activation by tpx2 0.4930556805332485 1.645572280139867 0.0998518500788991 1.0 0.7615201340140082 34 Q13561,Q13409,Q14203,Q9BV73,Q66GS9,Q15154,P06493,O95684,O75935,O43805,Q99996,O94927,Q9H6D7,P41208 14 +Activation of nmda receptors and postsynaptic events 0.4929737665852677 1.6379501468028503 0.1014320938273702 1.0 0.7615201340140082 26 P68371,P35609,Q12959,Q14168,P07196,P51812,Q13555,O14936,P16220,Q9BUF5,P27361,Q15418 12 +Extra nuclear estrogen signaling 0.5417791506190882 1.6318711021916334 0.1027066428337772 1.0 0.7615201340140082 16 P31749,P16220,P31751 3 +Synaptic adhesion like molecules 0.668913410394921 1.6262415742989451 0.1038982752406569 1.0 0.7615201340140082 7 O95197 1 +Formation of atp by chemiosmotic coupling 0.6152395887521775 1.6199455186472018 0.1052439806815188 1.0 0.7615201340140082 10 P00846 1 +Recruitment of numa to mitotic centrosomes 0.4853959157727193 1.6147702620845774 0.1063604553381123 1.0 0.7615201340140082 40 Q13409,Q9BV73,Q15154,O94927,Q7Z4H7,Q9BSJ2,P41208,P68371,P61163,Q13561,O75935,Q9H6D7,Q14203,Q66GS9,O95684,O43805,Q99996,Q9BUF5,P06493 19 +O linked glycosylation 0.6807136994337148 1.607456803217716 0.1079541980022411 1.0 0.7615201340140082 6 Q9Y2G5,Q10471,Q86SF2,Q10472 4 +Programmed cell death 0.3574902544593629 1.6064701197173417 0.1081706550746661 1.0 0.7615201340140082 103 O43633,P28072,Q13813,P31751,P28074,O60313,P20618,P61289,P28070,P31749,O00429,Q06323,O15294,P25054,P08670,Q9NR28,P51665,Q9UL46,P49721,P35611,O00231,Q99436,Q8WUX9 23 +Signaling by braf and raf1 fusions 0.4869445431877229 1.5992757161144595 0.109759352867518 1.0 0.7615201340140082 23 Q6WCQ1,Q13555,Q9NRY5,Q53H12,Q99996,Q96PU8 6 +Cyclin a cdk2 associated events at s phase entry 0.4786552419516454 1.592309810531179 0.111315109675371 1.0 0.7615201340140082 44 P28072,P28070,O00231,P31751,P31749,Q99436,P51665,P28074,P20618,P49721,P61289,Q06323 12 +Beta catenin phosphorylation cascade 0.6592621401849126 1.5802801137812774 0.1140427319245716 1.0 0.7615201340140082 7 P30154,P25054,P49841 3 +Signaling by ctnnb1 phospho site mutants 0.6592621401849126 1.5802801137812774 0.1140427319245716 1.0 0.7615201340140082 7 P30154,P25054,P49841 3 +Cd28 co stimulation 0.5871542646892125 1.5696286686530716 0.1165015248637317 1.0 0.7615201340140082 11 P31751 1 +Synthesis of pe 0.8507992895204224 1.5526962703892448 0.1204957137718454 1.0 0.7680913992031791 3 Q9HBU6,P35790 2 +Signaling by notch 0.4454270971030388 1.5486297177368809 0.1214707578320406 1.0 0.7689404740677396 60 P67809,P28072,P28070,O00231,P31749,Q99436,P51665,P28074,P16615,P20618,Q15363,P16220,Q9UBV2,P49721,P61289,Q06323 16 +Insulin receptor recycling 0.6012814102497654 1.5453207453218312 0.122268699958028 1.0 0.7689404740677396 10 Q9UI12,Q9Y487,Q93050,Q15904,Q9Y5K8,P21281 6 +Ros and rns production in phagocytes 0.6187456906070106 1.5441883083653922 0.1225427203797742 1.0 0.7689404740677396 9 Q93050 1 +Er quality control compartment erqc 0.7577080948180235 1.5400126427461127 0.123557271720109 1.0 0.7689404740677396 4 Q9UBV2 1 +Interaction between l1 and ankyrins 0.7560870043327064 1.5332999331980597 0.1252019710782232 1.0 0.769964544604404 4 Q13813,Q01082 2 +Antigen presentation folding assembly and peptide loading of class i mhc 0.5146639508209057 1.5267675365326634 0.1268188267446208 1.0 0.7764872023486434 17 Q9NZ08,Q6P179 2 +Gastrin creb signalling pathway via pkc and mapk 0.6461361342553715 1.5175255357607869 0.1291340513194856 1.0 0.7770307570775946 7 P51812,P16220,P62993,P27361,Q15418 5 +Transport of small molecules 0.3846878118754487 1.5118129825162965 0.1305814457589713 1.0 0.7772540161286506 159 P55011,P28072,Q70HW3,P40855,Q9Y4W6,Q96QD8,P30519,P28074,P20618,P30825,Q10713,Q14997,Q9UBV2,P61289,Q8NEW0,Q9BPX6,P28070,P05023,Q13438,Q9Y6M7,Q93050,Q8IYU8,P21796,P98194,Q06323,Q8WTV0,P09601,Q8TB61,Q9Y487,Q13555,P51665,Q9UL46,Q9HD20,P49721,P45880,P35611,O00231,Q99436,Q9Y5K8,P16615,Q9UBX3,Q9C0H2,Q9NWR8 43 +Cellular response to chemical stress 0.3939871899418244 1.5068225050080184 0.1318561593845428 1.0 0.7772540161286506 76 P28072,P30519,Q8N8Q8,P28074,P20618,P42704,Q14997,P61289,P28070,Q8TCT9,Q86X55,Q06323,P09601,P00403,P51665,Q9UL46,P13073,P49721,O75880,O00231,Q99436 21 +Fgfr1 mutant receptor activation 0.6096745031173836 1.497378526834192 0.1342947924034054 1.0 0.7772540161286506 9 O95684,O95429 2 +Costimulation by the cd28 family 0.521223386028976 1.4969877308920476 0.1343964505348323 1.0 0.7772540161286506 16 P31749,P31751 2 +Defective cftr causes cystic fibrosis 0.4671855794452602 1.4919819532078151 0.1357038764394036 1.0 0.7772540161286506 44 P28072,P28070,O00231,Q13438,Q99436,P51665,P28074,P20618,Q9UL46,Q9UBV2,P49721,P61289,Q06323 13 +Neddylation 0.4026467521560988 1.4873405260783945 0.1369248961367337 1.0 0.7772540161286506 73 Q9BTE7,P28072,P28070,Q99627,Q92564,O00231,P61201,P51665,Q99436,P28074,P20618,Q9UL46,Q9Y5A7,P49721,Q14997,P61289,Q06323,Q9BT78 18 +Regulation of tp53 activity through association with co factors 0.7441930487136074 1.48398191263008 0.1378137191131079 1.0 0.7772540161286506 4 P31751 1 +Bbsome mediated cargo targeting to cilium 0.638475876138306 1.4807810584926786 0.1386649255624161 1.0 0.7772540161286506 7 P49368,P78371 2 +Signaling by erbb2 0.5281817816058698 1.4777721935113803 0.1394687634620461 1.0 0.7772540161286506 15 P31751 1 +Signaling by wnt 0.3437130941909402 1.4775651786738015 0.1395242004346324 1.0 0.7772540161286506 88 P28072,P31751,Q08209,P28074,P20618,Q14997,P61289,P28070,P31749,P30154,Q06323,P25054,P51665,Q9UL46,P49721,Q5T9L3,O00231,Q99436,O14641 19 +Bmal1 clock npas2 activates circadian gene expression 0.8303730017761977 1.4725835203401498 0.1408633711178715 1.0 0.7772540161286506 3 P43490,Q86X55 2 +Activation of bh3 only proteins 0.542320747661427 1.4614257333200624 0.1438986429238884 1.0 0.7791314345013735 13 P31751 1 +Signaling by fgfr1 in disease 0.5849613012120246 1.4575556777378451 0.1449630539958264 1.0 0.7791314345013735 10 O95684,O95429 2 +Rhobtb1 gtpase cycle 0.4658638370800088 1.4519613350573972 0.1465123564476786 1.0 0.7791314345013735 20 P78371,P61201,P08670,P38159,Q5VTR2,Q9BT78 6 +Signaling by pdgfr in disease 0.6879193257058435 1.4488176132799782 0.1473885236516852 1.0 0.7791314345013735 5 P62993,O43815,Q13439 3 +Mitotic g1 phase and g1 s transition 0.3706984630144934 1.4487943471416729 0.1473950229113658 1.0 0.7791314345013735 81 P28072,P20248,P31751,Q14566,P28074,P20618,Q92530,P61289,Q13200,Q13416,P11802,P28070,P25787,P31749,P30154,Q9NR33,Q06323,P30153,Q9Y619,O75419,P33993,P51665,O43242,P00374,Q9UL46,P17980,P24941,O00487,P49721,P33991,O00231,P25205,P31350,Q99436,P06493,Q9UBD5,Q9UNM6,P62191,P63208 39 +Tysnd1 cleaves peroxisomal proteins 0.6875152050477159 1.4470443040700929 0.1478845154795984 1.0 0.7791314345013735 5 Q15067 1 +Signaling by hedgehog 0.425442220413786 1.446017699442946 0.1481722375218934 1.0 0.7791314345013735 64 P28072,Q2M1P5,P28074,P20618,Q92530,Q9UBV2,Q14997,Q9Y297,P61289,Q13200,P68371,P28070,P25787,Q13438,Q06323,P49841,P07237,P51665,O43242,Q9UL46,Q8NCM8,P17980,O00487,Q9BUF5,P49721,Q7Z4L5,O00231,Q96J02,Q99436,Q9UNM6,P62191 31 +Cooperation of prefoldin and tric cct in actin and tubulin folding 0.5014910808250084 1.4368355239025146 0.1507647338854794 1.0 0.7791314345013735 17 P68371,Q9UHV9,P50991,P78371,P49368,Q9BUF5,O15212 7 +Degradation of dvl 0.4651236043326607 1.4361046321866648 0.1509725702052453 1.0 0.7791314345013735 39 P28072,P28070,O00231,Q99436,P51665,P28074,P20618,Q9UL46,O14641,P49721,P61289,Q06323 12 +Unfolded protein response upr 0.46072247396261 1.4263283653440022 0.1537735805426252 1.0 0.7791314345013735 43 Q9Y5M8,O43731,Q13868,P51858,Q9NWM8,P43307 6 +Negative regulation of notch4 signaling 0.4623275142601112 1.418192589264833 0.1561345449239717 1.0 0.7791314345013735 40 P28072,P28070,O00231,P31749,Q99436,P51665,P28074,P20618,P49721,P61289,Q06323 11 +Downstream signaling events of b cell receptor bcr 0.4586772835578623 1.4171667333239122 0.1564341854435313 1.0 0.7791314345013735 44 P28072,P62942,P28070,O00231,Q08209,Q99436,P51665,P28074,P20618,Q9UL46,P49721,Q14997,P61289,Q06323 14 +Regulation of gene expression in beta cells 0.9508730393607586 1.4126083353837664 0.1577709168433121 1.0 0.7791314345013735 2 P31751 1 +Downregulation of erbb2 erbb3 signaling 0.9508730393607586 1.4126083353837664 0.1577709168433121 1.0 0.7791314345013735 2 P31751 1 +Runx2 regulates genes involved in cell migration 0.9508730393607586 1.4126083353837664 0.1577709168433121 1.0 0.7791314345013735 2 P31751 1 +Nephrin family interactions 0.5734967115224276 1.3956091670041488 0.1628322204307124 1.0 0.7791314345013735 10 P35609,Q13813,P12814,O43707 4 +Foxo mediated transcription 0.5373684492501786 1.3916016831457716 0.1640430489052771 1.0 0.7791314345013735 12 P31751 1 +Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation 0.7219245511012153 1.3913797465598432 0.1641103029483428 1.0 0.7791314345013735 4 P31749 1 +Negative regulation of the pi3k akt network 0.5139531169051653 1.3865393001357311 0.1655822885350253 1.0 0.7791314345013735 15 P31749,O43815,P30154,P31751 4 +Regulation of mrna stability by proteins that bind au rich elements 0.414427642626546 1.385190369733463 0.1659942646233363 1.0 0.7791314345013735 66 P28072,P28070,O00231,P31749,Q99436,Q5RKV6,P51665,P28074,P20618,Q01105,Q13868,P49721,P61289,Q06323,Q92973 15 +Transferrin endocytosis and recycling 0.5537843639895342 1.3821714403057723 0.1669190670524787 1.0 0.7791314345013735 11 Q93050 1 +Ptk6 regulates proteins involved in rna processing 0.8063943161634068 1.378355960665089 0.1680934133341289 1.0 0.7791314345013735 3 O75525,P23246 2 +Rora activates gene expression 0.8062395284993411 1.377747375059657 0.1682812988927666 1.0 0.7791314345013735 3 Q86X55 1 +Hedgehog ligand biogenesis 0.45507416146781 1.3768735174473945 0.1685513561743659 1.0 0.7791314345013735 43 P28072,P28070,O00231,Q13438,Q99436,P51665,P28074,P20618,Q9UL46,Q9UBV2,P49721,P61289,Q06323 13 +Cross presentation of soluble exogenous antigens endosomes 0.4580520101053865 1.3709194734118049 0.1704000601259703 1.0 0.7846851831800005 38 P28072,P28070,O00231,Q9UBG0,Q99436,P51665,P28074,P20618,Q9UL46,P49721,P61289,Q06323 12 +Abc family proteins mediated transport 0.4373691311493323 1.366291069746274 0.1718476228467484 1.0 0.7846851831800005 55 P28072,P40855,P28070,O00231,Q13438,Q99436,P51665,P28074,P20618,Q9UL46,Q9UBV2,P49721,P61289,Q06323 14 +Switching of origins to a post replicative state 0.4249524578085664 1.365534262104194 0.1720851920773152 1.0 0.7846851831800005 61 P28072,P20248,Q14566,P28074,P20618,Q92530,Q14997,P61289,Q13200,Q13416,P28070,P25787,Q9UJX3,Q96DE5,Q06323,Q9Y619,P33993,P51665,O43242,Q9UL46,P17980,P24941,O00487,P49721,P33991,O00231,P25205,Q99436,Q9UBD5,Q9UNM6,Q9UJX4,P62191 32 +Caspase mediated cleavage of cytoskeletal proteins 0.6686267763093711 1.364013588963934 0.1725632888511892 1.0 0.7846851831800005 5 P35611,P08670 2 +Unwinding of dna 0.5812982700621843 1.350075424115251 0.1769917905653777 1.0 0.7865161424050924 9 P25205,O75419,P33993,Q9BRT9,P33991 5 +Incretin synthesis secretion and inactivation 0.7119712227347766 1.349906174699113 0.1770460808087746 1.0 0.7865161424050924 4 P67812 1 +Synthesis secretion and inactivation of glucagon like peptide 1 glp 1 0.7119712227347766 1.349906174699113 0.1770460808087746 1.0 0.7865161424050924 4 P67812 1 +Transcriptional regulation by runx2 0.4355018172703421 1.3482822154682983 0.1775676299914903 1.0 0.7865161424050924 55 P28072,P31751,P28074,P20618,Q14997,P61289,Q13200,P11802,P28070,P25787,P31749,Q07812,Q06323,P49841,P51665,Q9UL46,P17980,P49721,O00231,Q99436,P06493 21 +Regulation of runx3 expression and activity 0.4561038433610947 1.3468249867741835 0.1780366053008661 1.0 0.7865161424050924 36 P28072,P28070,O00231,Q99436,P51665,P28074,P20618,P49721,P61289,Q06323 10 +Signaling by notch4 0.4480640993598997 1.3153347517654292 0.1883974236158454 1.0 0.7981865807301114 43 P28072,P28070,O00231,P31749,Q99436,P51665,P28074,P20618,P49721,P61289,Q06323 11 +Asymmetric localization of pcp proteins 0.4507117217839836 1.313137015767725 0.1891367827914685 1.0 0.7981865807301114 39 P28072,P28070,O00231,Q99436,P51665,P28074,P20618,Q9UL46,O14641,P49721,P61289,Q06323 12 +Hedgehog off state 0.4299153983678192 1.3118976773496895 0.1895546613178196 1.0 0.7981865807301114 56 P28072,Q2M1P5,P28074,P20618,Q92530,Q14997,Q9Y297,P61289,Q13200,P68371,P28070,P25787,Q06323,P49841,P51665,O43242,Q9UL46,Q8NCM8,P17980,O00487,Q9BUF5,P49721,Q7Z4L5,O00231,Q96J02,Q99436,Q9UNM6,P62191 28 +Depolymerisation of the nuclear lamina 0.5737389319652242 1.3106498269454327 0.189976096902122 1.0 0.7981865807301114 9 P02545,P50402,P42167,P06493 4 +O linked glycosylation of mucins 0.7000296120817227 1.3001070234238212 0.1935642908159751 1.0 0.7981865807301114 4 Q10471,Q86SF2,Q10472 3 +Class i mhc mediated antigen processing presentation 0.3461449551898402 1.2956132552030497 0.1951087601061187 1.0 0.7981865807301114 119 P28072,Q9UBG0,P28074,P20618,Q14997,Q9Y297,P61289,Q9Y508,P28070,Q7Z7E8,Q9NZ08,P55786,Q06323,Q03518,Q92990,P51665,Q05086,Q9UL46,P52888,P49721,O00231,Q9UBS8,Q6P179,Q99436,P09429,Q9UJX4 26 +Intracellular signaling by second messengers 0.3299342757275617 1.2929991125885372 0.1960113660218225 1.0 0.7981865807301114 94 P28072,P31751,Q8TBX8,P28074,P20618,P61289,P28070,P31749,P30154,Q06323,O43865,P51665,Q9UL46,P16220,P49815,P49721,O00231,Q99436,O43815 19 +Signaling by the b cell receptor bcr 0.4400433496864697 1.2908229136794327 0.1967650904042821 1.0 0.7981865807301114 48 P28072,P62942,P28070,O00231,Q08209,O43865,P51665,Q99436,P28074,P20618,Q9UL46,P49721,Q14997,P61289,Q06323 15 +Selective autophagy 0.4489621700003469 1.281325229895618 0.2000794545798008 1.0 0.7981865807301114 31 Q8N4H5,P08670,Q9NS69,Q8IWA4,P21796 5 +Mrna decay by 3 to 5 exoribonuclease 0.4974357684557883 1.2800790615846962 0.2005173317628021 1.0 0.7981865807301114 15 Q6PGP7,Q13868,Q969T7 3 +Signaling by hippo 0.5966212211025501 1.2787583423357232 0.2009821676157961 1.0 0.7981865807301114 7 Q9UDY2,Q07157,Q13043,Q4VCS5,O14641,P31946 6 +Mitotic prometaphase 0.3294931918847364 1.2768500374894094 0.201655196051854 1.0 0.7981865807301114 95 Q13409,Q9BV73,Q15154,O94927,Q9Y266,Q9UQE7,Q9NTJ3,P41208,Q9BSJ2,Q13561,Q8NFH4,P30154,Q8NBT2,O75935,Q15005,Q9H6D7,Q13257,Q14203,Q66GS9,O95684,O43805,Q99996,Q9BPX3,Q2NKX8,Q29RF7,P06493 26 +Degradation of axin 0.4466353177765253 1.2702739951438422 0.2039870479558578 1.0 0.7981865807301114 37 P28072,P28070,O00231,Q99436,P51665,P28074,P20618,Q9UL46,P49721,P61289,Q06323 11 +Regulation of ras by gaps 0.4456390527336042 1.2654255976125022 0.2057188039750044 1.0 0.7981865807301114 38 P28072,P28070,O00231,Q99436,P51665,P28074,P20618,Q9UL46,P49721,P61289,Q06323 11 +Cardiac conduction 0.5329692505026165 1.2642272000856225 0.20614849066823 1.0 0.7981865807301114 11 P16615,O43865,Q99996,P05023 4 +N glycan trimming and elongation in the cis golgi 0.9121041728322 1.2611289750727577 0.2072623827693578 1.0 0.7981865807301114 2 P33908 1 +Runx1 regulates transcription of genes involved in differentiation of hscs 0.443106533366938 1.258387913594364 0.2082515008191858 1.0 0.7981865807301114 41 P28072,P28070,O00231,Q99436,P51665,P28074,P20618,Q03164,Q9UL46,P49721,P61289,Q06323 12 +Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 0.3967051816518617 1.2510313993746347 0.2109230218653301 1.0 0.7981865807301114 68 P22695,Q8N8Q8,P03886,O14949,P42704,Q86Y39,P00846,O75964,Q9UDW1,P56556,P06576,O43676,Q9NPL8,P00403,O96000,P24539,P13073,O75880,O43674 19 +Degradation of beta catenin by the destruction complex 0.4329130090299056 1.2489700637043235 0.2116760234014814 1.0 0.7981865807301114 50 P28072,P28070,O00231,P30154,P51665,P25054,Q99436,P28074,P20618,Q9UL46,P49721,Q14997,P61289,Q06323 14 +Mastl facilitates mitotic progression 0.6423990836259814 1.248383489616259 0.2118906523661452 1.0 0.7981865807301114 5 P30154,O43768 2 +Smooth muscle contraction 0.5130900050998948 1.2477421044368668 0.2121255167986184 1.0 0.7981865807301114 12 P67936,P06753,P09493 3 +Regulation of hmox1 expression and activity 0.4355947480445615 1.2396245660838028 0.2151142899293243 1.0 0.8050926239714122 47 P28072,P28070,O00231,P09601,Q8TCT9,Q99436,P51665,P28074,P20618,Q9UL46,P49721,P61289,Q06323 13 +Abc transporter disorders 0.4373442472368602 1.2366324475526462 0.2162235680054052 1.0 0.8070804837848814 45 P28072,P28070,O00231,Q13438,Q99436,P51665,P28074,P20618,Q9UL46,Q9UBV2,P49721,P61289,Q06323 13 +Interleukin 1 family signaling 0.4312280320066234 1.2333162310036885 0.2174578045767279 1.0 0.8081638249054978 50 P28072,P28070,Q9H3S7,Q13501,O00231,Q99436,P51665,P28074,P20618,Q9UL46,P09429,P49721,Q14997,P61289,Q06323 15 +Tcf dependent signaling in response to wnt 0.4045858255726093 1.2267105354117027 0.2199314065171631 1.0 0.8081638249054978 64 P28072,P28070,O00231,P31751,P31749,P30154,P51665,P25054,Q99436,P28074,P20618,Q9UL46,O14641,P49721,Q14997,P61289,Q06323 17 +Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde 0.7669837490976398 1.2234888435846716 0.2211451154111032 1.0 0.8081638249054978 3 P16220 1 +Camk iv mediated phosphorylation of creb 0.7669837490976398 1.2234888435846716 0.2211451154111032 1.0 0.8081638249054978 3 P16220 1 +Interleukin 1 signaling 0.4324167127866221 1.2211125229719004 0.2220434188287814 1.0 0.8090598126301333 48 P28072,P28070,Q13501,O00231,Q99436,P51665,P28074,P20618,Q9UL46,P09429,P49721,Q14997,P61289,Q06323 14 +Initiation of nuclear envelope ne reformation 0.447971227917774 1.2188672789382715 0.2228945706925271 1.0 0.8090598126301333 19 Q86XL3,P20700,Q86Y07,Q8IXJ6,P06493,P02545,P50402,P42167,Q14739,P30153 10 +Diseases of signal transduction by growth factor receptors and second messengers 0.3605789499860783 1.2059082807651311 0.2278528573908493 1.0 0.8132521824437638 154 P28072,P62942,P31751,P28074,Q13439,P20618,Q9UBV2,Q14997,P61289,P28070,P31749,Q6WCQ1,P33176,Q13438,P30154,Q9NRY5,Q53H12,O95429,Q06323,Q01082,Q13501,Q14203,P49841,P12270,Q13555,P25054,P51665,O95684,Q9UL46,Q99996,P17980,Q16543,Q96PU8,P62993,P67936,P16220,P49721,P49815,P35269,Q96RT1,O00231,P06753,Q99436,O43815,P02545,P35579 46 +Creb phosphorylation 0.7613972764949539 1.20157932745494 0.2295265548191878 1.0 0.8132521824437638 3 Q15418,P16220 2 +Cytochrome p450 arranged by substrate type 0.7602713197737714 1.1971657334191088 0.2312419630736504 1.0 0.8132521824437638 3 Q16850 1 +Regulation of plk1 activity at g2 m transition 0.4364300094760958 1.1951561552419756 0.2320260252583157 1.0 0.8132521824437638 40 Q13561,Q13409,Q14203,Q9BV73,Q66GS9,Q15154,P06493,O95684,O75935,O43805,Q99996,O94927,Q9H6D7,Q9Y297,P41208 15 +Methionine salvage pathway 0.7595155234901437 1.1942035792114962 0.2323983433584526 1.0 0.8132521824437638 3 Q13126 1 +Wnt ligand biogenesis and trafficking 0.5910615738515779 1.1903610727077771 0.2339045061566858 1.0 0.8163267264868335 6 Q96QK1,Q5T9L3 2 +Metabolism of polyamines 0.4348170182613859 1.1768317637506074 0.2392626618578037 1.0 0.8240639983637384 39 P28072,P28070,O00231,Q99436,P51665,P28074,P20618,Q9UL46,P49721,P61289,Q06323 11 +Metabolism of steroid hormones 0.5746404746238325 1.1721352218191934 0.2411427708265927 1.0 0.8240639983637384 7 Q14849,P30536 2 +Pi3k akt signaling in cancer 0.4703463006640334 1.1586078247580645 0.2466160779399695 1.0 0.8243949166661635 16 P31749,P49841,P31751,O43815,P16220,P49815,P62993 7 +Clec7a dectin 1 induces nfat activation 0.8845812370523831 1.1543370014260428 0.2483620322856654 1.0 0.8243949166661635 2 O43865 1 +Calcineurin activates nfat 0.8845812370523829 1.154337001426042 0.2483620322856659 1.0 0.8243949166661635 2 P62942 1 +Transcriptional regulation by runx3 0.4305831586115844 1.1494282190659704 0.2503794495691638 1.0 0.8243949166661635 41 P28072,P28070,O00231,Q99436,P51665,P28074,P20618,P49721,P61289,Q06323 10 +Ncam signaling for neurite out growth 0.5565523283564596 1.1480438963799335 0.2509504429808404 1.0 0.8243949166661635 8 Q13813,Q01082,O15020,P16220 4 +Rsk activation 0.6591316364291089 1.1296059381716197 0.2586423077180457 1.0 0.8331033812179214 4 P51812,Q15418 2 +Sema4d in semaphorin signaling 0.5389718325369571 1.1287529773575782 0.2590020540462592 1.0 0.8331033812179214 9 P35579,P35580,O75116,Q7Z406 4 +Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip 0.7362698368126885 1.103325568869947 0.2698858067389482 1.0 0.8497954505322175 3 P67812 1 +Synthesis secretion and deacylation of ghrelin 0.7362698368126885 1.103325568869947 0.2698858067389482 1.0 0.8497954505322175 3 P67812 1 +Stabilization of p53 0.4261605565508209 1.102420778493297 0.2702787822609631 1.0 0.8497954505322175 39 P28072,P28070,O00231,Q99436,P51665,P28074,P20618,Q9UL46,P49721,P61289,Q06323 11 +Clec7a dectin 1 signaling 0.4179169668835858 1.0882444618624352 0.2764872012653336 1.0 0.8555459111837848 48 P28072,P28070,O00231,Q08209,O43865,P51665,Q99436,P28074,P20618,Q9UL46,P49721,Q14997,P61289,Q06323 14 +Rnd2 gtpase cycle 0.4676306721566989 1.087059381749944 0.277010567231426 1.0 0.8555459111837848 15 P51648,Q9Y2I1,Q9NNW5,P38159,Q86UP2,Q07065 6 +Association of tric cct with target proteins during biosynthesis 0.4300348227330973 1.0852342949715803 0.2778178984449362 1.0 0.8561452234638651 19 P49368,O95302 2 +Synthesis of dna 0.3242271303156809 1.083455222841469 0.2786064155699306 1.0 0.8565953348873018 86 P28072,P20248,Q14566,P28074,P20618,Q92530,Q9Y2S7,Q14997,P61289,Q13200,Q13416,P28070,P25787,Q9UJX3,Q9NR33,Q96DE5,Q9BRT9,P40937,Q06323,Q9Y619,O75419,P33993,P51665,O43242,Q9UL46,P17980,P24941,O00487,P49721,P33991,O00231,P25205,Q99436,Q9UBD5,Q9UNM6,Q9UJX4,P62191,P63208 38 +Phosphorylation of the apc c 0.5009754932541323 1.0821380899688358 0.2791911729038125 1.0 0.8565953348873018 11 Q96DE5,Q9UJX4,P06493 3 +Degradation of gli1 by the proteasome 0.4216825829983613 1.076894159751437 0.2815275525314173 1.0 0.8599835083891874 42 P28072,P28070,O00231,Q99436,P51665,P28074,P20618,Q9UL46,P49721,Q14997,P61289,Q06323 12 +Orc1 removal from chromatin 0.4080047340479448 1.053130861448748 0.2922810202838364 1.0 0.8740844153497683 53 P28072,P20248,Q14566,P28074,P20618,Q92530,Q14997,P61289,Q13200,Q13416,P28070,P25787,Q06323,Q9Y619,P33993,P51665,O43242,Q9UL46,P17980,P24941,O00487,P49721,P33991,O00231,P25205,Q99436,Q9UBD5,Q9UNM6,P62191 29 +Cdt1 association with the cdc6 orc origin complex 0.4189440601919039 1.0528602858274596 0.2924050300632821 1.0 0.8740844153497683 42 P28072,P28074,P20618,Q92530,Q14997,P61289,Q13200,Q13416,P28070,P25787,Q06323,Q9Y619,P51665,O43242,Q9UL46,P17980,O00487,P49721,O00231,Q99436,Q9UBD5,Q9UNM6 22 +Tnfr2 non canonical nf kb pathway 0.4182417038370108 1.0466964412963042 0.2952396055834856 1.0 0.8769244455203105 42 P28072,P28070,O00231,Q99436,P51665,P28074,P20618,Q9UL46,P49721,Q14997,P61289,Q06323 12 +Dectin 1 mediated noncanonical nf kb signaling 0.4182417038370108 1.0466964412963042 0.2952396055834856 1.0 0.8769244455203105 42 P28072,P28070,O00231,Q99436,P51665,P28074,P20618,Q9UL46,P49721,Q14997,P61289,Q06323 12 +Transport to the golgi and subsequent modification 0.3461143598574411 1.0427319284688814 0.2970724660124879 1.0 0.8804950372684356 79 Q13813,Q9BVK6,Q13190,P49257,P24390,Q5JRA6,O95249,Q13561,O60476,Q08379,Q15363,O75935,P33908,Q01082,Q14203,O43731,P35606,P49755,O60763,O15027,O15020,Q14789,Q9Y6B6,Q96PC5 24 +Pregnenolone biosynthesis 0.5951242354623427 1.0400407000918084 0.2983209920433141 1.0 0.8823222561281069 5 Q14849,P30536 2 +Signaling by erbb4 0.5067939967223172 1.0324463279245513 0.3018630786245047 1.0 0.8890313454848282 10 P16949,Q96J02,P00533,P61201,P62993 5 +Ca2 pathway 0.5909458999543769 1.0217017148045753 0.306922099251113 1.0 0.8920708681758583 5 Q08209 1 +Ngf stimulated transcription 0.6324374384219716 1.0188698442689257 0.3082647617540055 1.0 0.8920708681758583 4 P16220 1 +Miscellaneous transport and binding events 0.5527137287164159 1.01098182113393 0.3120251306100772 1.0 0.894429327169749 6 Q9UEY8,P35611 2 +Peroxisomal lipid metabolism 0.4616138120856907 1.0047505081968038 0.315017000654703 1.0 0.9002655316660522 14 Q15067,P51648 2 +Intraflagellar transport 0.4614633327675404 1.0038046031386538 0.3154728052259925 1.0 0.9002655316660522 14 Q7Z4L5,P68371,A0AVF1,Q8NCM8,Q9BUF5,Q92973 6 +Transcriptional regulation by ventx 0.4710840676682173 0.9975826826169788 0.318481761876038 1.0 0.9017503986463714 12 Q96DE5,Q9UJX4 2 +Signaling by vegf 0.4132804178310343 0.989250668019398 0.3225405138848844 1.0 0.9038585491899026 31 Q9UQB8,P31749,O43865,P31751 4 +G1 s dna damage checkpoints 0.4120015093126083 0.987507529466184 0.3233938935621316 1.0 0.9038585491899026 41 P28072,P28070,O00231,Q99436,P51665,P28074,P20618,Q9UL46,P49721,P61289,Q06323 11 +Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 0.4052703209248158 0.9815108980808724 0.3263408628466475 1.0 0.9093250389898602 49 P28072,P28070,O00231,Q99436,P51665,P28074,P20618,Q96DE5,Q9UL46,P49721,P61289,Q9UJX4,Q06323 13 +Rac2 gtpase cycle 0.412359601405095 0.9783788887503386 0.3278869655680256 1.0 0.9110516915367288 36 Q9NSV4,Q86XL3,O15173,Q13505,P50402,Q9H2K8,Q7L576 7 +Pp2a mediated dephosphorylation of key metabolic factors 0.7038289565109774 0.977613010792272 0.3282657599161709 1.0 0.9110516915367288 3 P30154 1 +Toll like receptor tlr1 tlr2 cascade 0.4043296316437397 0.9677743546223092 0.3331570743294552 1.0 0.9179978794950656 21 Q9BQ95,P51812,P30154,P09429,P16220,O15111,Q9Y297,Q15418,P27361,P63208,P30153 11 +Ion homeostasis 0.4938591742343278 0.962034303596932 0.336032372758436 1.0 0.9199851024058764 10 P16615,O43865,P05023 3 +Hedgehog on state 0.4077142047017375 0.9592315984268468 0.3374420853837128 1.0 0.9200569359290294 43 P28072,P28070,O00231,Q99436,P51665,P28074,P20618,Q9UL46,P49721,P61289,Q06323 11 +Nuclear events kinase and transcription factor activation 0.4578209673700642 0.9462581937531442 0.3440169109595656 1.0 0.923107131927887 13 P51812,P30154,P50570,P27361,P16220,Q15418 6 +Cellular response to hypoxia 0.4067430661171163 0.9382982500539392 0.348091158815818 1.0 0.927357362036034 40 P28072,P28070,O00231,Q99436,P51665,P28074,P20618,Q9UL46,P49721,P61289,Q06323 11 +Uch proteinases 0.4012238373041232 0.9351845016004752 0.3496932242388879 1.0 0.9298509353095 48 P28072,Q9Y4E8,P28070,O00231,Q99436,P51665,P28074,P20618,Q9UL46,P49721,P61289,Q06323,O15294 13 +Auf1 hnrnp d0 binds and destabilizes mrna 0.4045644160017344 0.9267666058673996 0.3540477268687112 1.0 0.9377036365010324 42 P28072,P28074,P20618,Q92530,Q14997,P61289,Q14103,Q13200,P28070,P25787,Q04637,P11142,Q06323,P51665,O43242,Q9UL46,P17980,O00487,P49721,O00231,Q99436,Q9UNM6 22 +Epha mediated growth cone collapse 0.4867222286435438 0.9232840339415008 0.3558592060398728 1.0 0.9377036365010324 10 P35579,P35580,O75116,Q7Z406 4 +Signaling by wnt in cancer 0.4988166081710907 0.918949677846073 0.3581218939799755 1.0 0.9397333909700109 9 P25054 1 +Rab gefs exchange gtp for gdp on rabs 0.4035715832673833 0.9160533603788322 0.3596389083370699 1.0 0.9403346276784156 29 Q14C86,P31751 2 +Fc epsilon receptor fceri signaling 0.3893538794587436 0.914656866621644 0.3603717949913698 1.0 0.9403346276784156 56 P28072,Q08209,P28074,P20618,Q92530,Q14997,Q9Y297,P61289,Q13200,P28070,P25787,O15111,P27361,Q06323,O43865,P51665,O43242,Q9UL46,P17980,O00487,P62993,P49721,O00231,Q99436,P49427,Q9UNM6,P62191,P63208 28 +Ub specific processing proteases 0.358380522069336 0.9088110200582148 0.3634498885635935 1.0 0.9453869487985986 71 P28072,Q9Y4E8,P28070,O00231,Q96RU2,Q99436,P51665,P28074,P20618,P49721,P61289,P21796,Q96K76,Q06323,P45880 15 +Deubiquitination 0.3021367558939985 0.8930710734364473 0.3718191125822581 1.0 0.9472964628673451 93 P28070,Q9Y4E8,P28072,O00231,Q06323,O15294,Q96RU2,Q99436,P25054,P51665,P28074,P20618,P61289,P21796,Q96K76,P49721,P45880 17 +Translation of sars cov 1 structural proteins 0.5266084378834034 0.8897711051403064 0.3735888047875577 1.0 0.9472964628673451 6 Q10472,P27824,P49841 3 +Regulation of runx2 expression and activity 0.3993301258868433 0.8853132995890144 0.3759876788993468 1.0 0.9472964628673451 43 P28072,P28070,O00231,Q99436,P51665,P28074,P20618,Q9UL46,P49721,P61289,Q06323 11 +Folding of actin by cct tric 0.5019419612935798 0.8740619031974802 0.3820845430240627 1.0 0.954192096411842 8 P49368,P78371 2 +Scf skp2 mediated degradation of p27 p21 0.39851634176752 0.8738644694453166 0.3821920661465601 1.0 0.954192096411842 42 P28072,P28070,O00231,Q99436,P51665,P28074,P20618,P49721,P61289,Q06323 10 +Mapk targets nuclear events mediated by map kinases 0.4759343932521035 0.8649090887908226 0.3870886886756564 1.0 0.9598149367517164 10 P51812,P30154,P16220,P27361,Q15418 5 +Myoclonic epilepsy of lafora 0.8046759396271107 0.8520829949355011 0.3941680294757672 1.0 0.9628219143323196 2 P13807 1 +Pexophagy 0.8043799940810912 0.8509960767272261 0.3947715321563136 1.0 0.9628219143323196 2 Q13501 1 +Retrograde transport at the trans golgi network 0.3975814078141395 0.8440714754158172 0.3986294661748486 1.0 0.9646762651786156 19 O43752,Q9UID3,Q13439 3 +Glycerophospholipid biosynthesis 0.3941806421095193 0.8403824264109605 0.400693999207836 1.0 0.967766129574635 29 Q9NPH0,Q9HCL2,Q8N2A8,Q9HBU6,P35790 5 +Copi mediated anterograde transport 0.383811900314716 0.8341512608478583 0.4041957521509824 1.0 0.9723271527617496 54 Q13813,Q13409,Q9BVK6,Q13190,P24390,O95249,P61163,Q13561,P68371,Q08379,Q15363,O75935,Q01082,Q9UJW0,Q14203,Q92538,O43731,Q9BUF5,P35606,P49755,O60763,O15020,Q14789 23 +Methylation 0.503477015077274 0.8288414767679559 0.4071941147839237 1.0 0.9723271527617496 7 P21964,P78417 2 +Sting mediated induction of host immune responses 0.5109275704042979 0.8176894755145493 0.4135345215295474 1.0 0.9723271527617496 6 P12956 1 +Signaling by flt3 fusion proteins 0.5438247308963103 0.817074559453539 0.4138858205367506 1.0 0.9723271527617496 5 P62993,Q01082 2 +Fceri mediated nf kb activation 0.3904374432720495 0.8167745705256564 0.4140572670497802 1.0 0.9723271527617496 45 P28072,P28070,O00231,P25787,Q99436,P51665,P49427,P28074,P20618,Q9UL46,Q9Y297,P17980,O15111,Q14997,P61289,Q06323,Q13200,P49721 18 +Intrinsic pathway of fibrin clot formation 0.7943178455164278 0.8142318811422044 0.4155121248073397 1.0 0.9723271527617496 2 P42785 1 +Formation of fibrin clot clotting cascade 0.7943178455164278 0.8142318811422044 0.4155121248073397 1.0 0.9723271527617496 2 P42785 1 +Toll like receptor 9 tlr9 cascade 0.3864162185686034 0.8132499818199417 0.4160747480802702 1.0 0.9723271527617496 23 Q9BQ95,P51812,P30154,Q15075,P09429,P16220,O15111,Q9Y297,Q15418,P27361,P30153 11 +Dag and ip3 signaling 0.4783811312790871 0.8132263327500987 0.4160883044195462 1.0 0.9723271527617496 9 O43865,P16220 2 +Formation of tubulin folding intermediates by cct tric 0.434733773108277 0.806067746884918 0.4202037874244602 1.0 0.9723271527617496 13 P50991,P78371,Q9BUF5,P49368 4 +Rho gtpases activate ktn1 0.4769758107360901 0.8060013070594694 0.4202420954521888 1.0 0.9723271527617496 9 Q9H0B6,P33176 2 +Rho gtpases activate cit 0.4510110943863221 0.7991024175657147 0.4242310279528434 1.0 0.9768811065120264 11 Q15058,P35579,P35580,Q7Z406 4 +Transcriptional regulation of granulopoiesis 0.4970193358158598 0.7981881022828213 0.4247613407255015 1.0 0.9768811065120264 7 Q03164 1 +Activation of kainate receptors upon glutamate binding 0.5764470276037654 0.7907386275058709 0.429096530149101 1.0 0.9814067069020936 4 Q9UBI6 1 +Apoptotic cleavage of cellular proteins 0.3992065080440671 0.7887738413219691 0.4302442010201155 1.0 0.9814067069020936 18 P25054,P35611,P08670 3 +Mitochondrial biogenesis 0.3878963637072027 0.7751964171413367 0.4382236049948762 1.0 0.9858980424494698 34 P00846,O75964,Q13505,P17152,Q9NX63,P06576,Q86X55,P16220,Q15648 9 +C type lectin receptors clrs 0.3793002415441787 0.7690996217031856 0.4418341727582739 1.0 0.9858980424494698 52 P28072,P28070,O00231,Q08209,O43865,P51665,Q99436,P28074,P20618,Q9UL46,P49721,Q14997,P61289,Q06323 14 +Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.3783925321433662 0.7671334518707157 0.4430021746184742 1.0 0.9858980424494698 21 Q5JRA6,P07942,O43852,Q86UP2,Q07065 5 +Butyrate response factor 1 brf1 binds and destabilizes mrna 0.4231630543402546 0.7646289163669682 0.4444925452498349 1.0 0.9858980424494698 14 Q13868,P31749 2 +The role of gtse1 in g2 m progression after g2 checkpoint 0.3805741687780313 0.762379960936548 0.4458332627262256 1.0 0.9858980424494698 50 P28072,P28074,P20618,Q92530,Q14997,P61289,Q13200,P68371,P28070,P25787,Q06323,P51665,O43242,Q9UL46,P17980,O00487,Q9BUF5,P49721,O00231,Q99436,P06493,Q9UNM6 22 +Pten regulation 0.3501712589494496 0.7615730690991739 0.4463148532224421 1.0 0.9858980424494698 69 P28072,P28070,O00231,P31751,P31749,Q99436,P51665,P28074,P20618,P49721,P61289,Q06323 12 +Interconversion of nucleotide di and triphosphates 0.3853109043289848 0.7538325346633524 0.45094978532435 1.0 0.9858980424494698 19 Q9H773,P31350 2 +Platelet aggregation plug formation 0.496299186324873 0.7511607159658205 0.4525559390546751 1.0 0.9858980424494698 6 P31749 1 +Integrin signaling 0.496299186324873 0.7511607159658205 0.4525559390546751 1.0 0.9858980424494698 6 P31749 1 +Constitutive signaling by overexpressed erbb2 0.5280040370087059 0.7497586073877625 0.4534001026164467 1.0 0.9858980424494698 5 Q96RT1,Q16543 2 +Chylomicron assembly 0.7750813850251581 0.7450789655507867 0.4562239842375613 1.0 0.9864968870288536 2 P07237 1 +Suppression of apoptosis 0.6419834303245701 0.7447086017649329 0.4564478980020934 1.0 0.9864968870288536 3 P23246 1 +Protein protein interactions at synapses 0.4199206026774951 0.7446188964738275 0.4565021411322632 1.0 0.9864968870288536 14 O95197,Q14168 2 +Peptide ligand binding receptors 0.484292624285047 0.7382255718950935 0.4603773859021751 1.0 0.9902724664398096 7 P07602,Q9BYT8,P42892,Q9NZJ7 4 +Class a 1 rhodopsin like receptors 0.484292624285047 0.7382255718950935 0.4603773859021751 1.0 0.9902724664398096 7 P07602,Q9BYT8,P42892,Q9NZJ7 4 +Platelet homeostasis 0.4497685919526465 0.7248344039353564 0.4685536267794634 1.0 0.9918497363740696 10 P16615 1 +Beta catenin independent wnt signaling 0.3712739952327317 0.7143921471810885 0.474984726458834 1.0 0.994780186109845 54 P28072,P28070,O00231,Q08209,Q99436,P51665,P28074,P20618,Q9UL46,O14641,P49721,P61289,Q06323 13 +Dna replication 0.2889119376618165 0.7075898913465013 0.4791999721387869 1.0 0.9973416233481626 92 Q14974,P28072,P20248,Q14566,P28074,P20618,Q92530,Q9Y2S7,Q14997,P61289,Q13200,Q13416,P28070,P25787,Q9UJX3,Q9NR33,Q96DE5,Q9BRT9,P40937,Q06323,Q9Y619,O75419,P33993,P51665,O43242,Q9UL46,P17980,P24941,O00487,P49721,P33991,O00231,P25205,Q99436,O60684,Q9UBD5,Q9UNM6,Q9UJX4,P62191,P63208 40 +Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 0.6317036461044854 0.7072980886979678 0.4793812530563159 1.0 0.9973416233481626 3 P11802 1 +E2f enabled inhibition of pre replication complex formation 0.4839204834160912 0.6955502354048934 0.4867105406740044 1.0 1.0 6 Q13416,Q9Y619,P06493 3 +Autophagy 0.3699259711903543 0.6910996245009964 0.4895029362534426 1.0 1.0 53 O43633,Q5MNZ6,Q13501,Q8N4H5,Q15388,P08670,Q9NS69,Q8WUX9,P50542,Q8IWA4,P49815,P21796,Q9Y4P1 13 +Aberrant regulation of mitotic exit in cancer due to rb1 defects 0.4536905158971078 0.6874677070896943 0.4917880438105968 1.0 1.0 9 Q9UJX4 1 +Diseases of immune system 0.7564368156259278 0.6796838382122227 0.4967046715840819 1.0 1.0 2 P09429 1 +Apc c mediated degradation of cell cycle proteins 0.3601839159859079 0.6706420299297681 0.502448600668278 1.0 1.0 59 P28072,P20248,P28074,P20618,Q92530,Q14997,Q9Y297,P61289,Q13200,P28070,P25787,Q9UJX3,Q96DE5,Q13257,Q06323,P51665,O43242,Q9UL46,P17980,P24941,O00487,P49721,O00231,Q99436,P06493,Q9UNM6,Q9UJX4,P62191 28 +Cooperation of pdcl phlp1 and tric cct in g protein beta folding 0.4152071105251558 0.66893289427551 0.5035382857464925 1.0 1.0 12 P50991,P78371,P49368 3 +Plasma lipoprotein remodeling 0.7528854690736935 0.6674311658491622 0.5044967641116274 1.0 1.0 2 P07237 1 +Amino acid transport across the plasma membrane 0.5070753302751985 0.6623387449024746 0.5077541512674539 1.0 1.0 5 P30825 1 +Tp53 regulates metabolic genes 0.3741396403558316 0.6605343686504527 0.5089109707072033 1.0 1.0 41 O75880,P31749,P31751,P49815,P00403,P13073,P42704 7 +Sulfur amino acid metabolism 0.4351647611267172 0.6480279270315088 0.5169668876951088 1.0 1.0 10 Q9UBX3,Q13126,Q9BV57,Q99707 4 +Ksrp khsrp binds and destabilizes mrna 0.3990224726044805 0.6472843740880895 0.5174479127514973 1.0 1.0 15 Q13868,P31749 2 +Pcp ce pathway 0.3686374143816543 0.6457320051462898 0.5184529295768692 1.0 1.0 49 P28072,P28070,O00231,Q99436,P51665,P28074,P20618,Q9UL46,O14641,P49721,P61289,Q06323 12 +Rab regulation of trafficking 0.3718207019691428 0.6427370861688235 0.5203947124007073 1.0 1.0 42 P31749,P31751,Q14C86,Q9UJY4,Q9Y3P9,P49815,Q5VZ89 7 +Synthesis of pc 0.5015063491212274 0.6394536340561882 0.5225278673798837 1.0 1.0 5 Q9NQZ5,P35790,Q8NF37 3 +Interleukin 17 signaling 0.3770593814262267 0.6338176709889168 0.52619981946609 1.0 1.0 18 P51812,P30154,Q15418,O15111,Q9Y297,P27361,P16220,P30153 8 +Opioid signalling 0.3670360577295148 0.6214074653683952 0.5343315613788018 1.0 1.0 19 P30154,P16220,O43865,Q08209 4 +Tcr signaling 0.365173654336984 0.6213510025370566 0.5343687028861375 1.0 1.0 50 P28072,P28074,P20618,Q92530,Q14997,Q9Y297,P61289,Q13200,P28070,P25787,O15111,Q06323,P51665,O43242,Q9UL46,P17980,O00487,P49721,O00231,Q99436,P49427,Q9UNM6,P62191,P63208 24 +Sensory processing of sound 0.3652816876588842 0.6088594297511145 0.542617617518695 1.0 1.0 19 Q13813,P20020,P35241,O00159,O14936,P15311,P35579,P52907,Q6IBS0,Q00013,Q01082 11 +Fceri mediated ca 2 mobilization 0.46376934107607 0.606734232021348 0.5440273005550669 1.0 1.0 6 O43865,Q08209 2 +The citric acid tca cycle and respiratory electron transport 0.2876645048173814 0.6050448782871708 0.5451491779703153 1.0 1.0 101 O95563,Q13423,P22695,P03886,O14949,P42704,Q86Y39,P00846,O75964,Q9UDW1,P56556,P06576,O43676,P21796,P00403,O96000,P13073,O75880,Q9P0J1 19 +Cargo concentration in the er 0.3918857570940128 0.6029037971296048 0.5465726898042818 1.0 1.0 15 Q5JRA6,Q15363,P49257,Q13190,P49755,Q96PC5 6 +Antigen processing cross presentation 0.3612520191803908 0.6011261980465848 0.5477559353895805 1.0 1.0 52 P28072,P28070,O00231,Q9UBG0,Q99436,P51665,P28074,P20618,Q9UL46,P09429,P49721,P61289,Q06323,Q03518 14 +Metabolism of cofactors 0.4535229566212723 0.5965300074066621 0.5508212137157025 1.0 1.0 7 P00374,P31749 2 +Oncogene induced senescence 0.4604444444444474 0.5923199579087479 0.5536363538584421 1.0 1.0 6 Q9HCE1,Q00534,P28482,P27361,P11802 5 +Maturation of sars cov 2 nucleoprotein 0.4887440758293713 0.5877088820423472 0.5567277127605779 1.0 1.0 5 Q99873,P78362,Q96SB4,P49841 4 +Er to golgi anterograde transport 0.3201649825639328 0.5817070278145876 0.5607640369461109 1.0 1.0 75 Q13813,Q9BVK6,P49257,Q13190,P24390,O95249,Q5JRA6,Q13561,Q08379,Q15363,O75935,Q01082,Q14203,O43731,P35606,P49755,O60763,O15027,O15020,Q14789,Q9Y6B6,Q96PC5 22 +Rhobtb gtpase cycle 0.3612014861035112 0.5791702963488672 0.562474271243568 1.0 1.0 29 Q5VTR2,P78371,P62995,P61201,P08670,Q16543,P38159,O75116,P12814,Q9BT78 10 +Tristetraprolin ttp zfp36 binds and destabilizes mrna 0.3925558516495761 0.5784221334753367 0.5629791542854814 1.0 1.0 14 Q13868,Q92973 2 +Dna replication pre initiation 0.3391733474771065 0.5750914526394559 0.5652294482937752 1.0 1.0 66 P28072,Q14974,Q14566,P28074,P20618,Q92530,Q14997,P61289,Q13200,Q13416,P28070,P25787,Q9NR33,Q06323,Q9Y619,O75419,P33993,P51665,O43242,Q9UL46,P17980,P24941,O00487,P49721,P33991,O00231,P25205,Q99436,O60684,Q9UBD5,Q9UNM6,P62191 32 +Carboxyterminal post translational modifications of tubulin 0.4561373680380234 0.5737615775462215 0.5661291524457928 1.0 1.0 6 Q9BUF5,Q14166 2 +M phase 0.3415906715811144 0.572880038301238 0.5667259212482088 1.0 1.0 202 O43633,Q12769,P28072,Q13409,P20700,Q9BV73,Q15154,P28074,O43768,P20618,Q92530,O94927,Q14997,Q9Y266,P61289,Q9UQE7,Q9NTJ3,Q7Z4H7,Q13200,P41208,Q9BSJ2,Q13561,P28070,Q8NFH4,P68371,P25787,P61163,P53990,Q9UJX3,Q08379,Q8NBT2,P30154,Q96DE5,Q01105,O75935,Q15005,Q99567,P42167,Q8N1F7,Q9H6D7,Q13257,Q14739,Q06323,Q86XL3,Q9BTX1,Q14203,P12270,Q66GS9,Q86Y07,P51665,O43242,O95684,Q9UL46,O43805,Q99996,P17980,Q9BUF5,P49721,Q92973,Q9BPX3,O00231,Q2NKX8,Q29RF7,Q8IXJ6,Q99436,O60763,P06493,P02545,Q15021,Q8WUX9,P50402,Q9UJX4,Q9UPP1,O15504 74 +Gpcr ligand binding 0.4201525203477209 0.5705196100004258 0.5683253255244733 1.0 1.0 10 Q9BYT8,Q9UBI6,P07602,P42892,Q9NZJ7 5 +Disorders of transmembrane transporters 0.3139087602630039 0.5680821110281995 0.569979214132611 1.0 1.0 77 P28072,P28070,Q9BTX1,O00231,Q13438,Q99436,P51665,P28074,P20618,Q99567,Q8N1F7,Q9UBV2,P61289,Q06323,P49721 15 +Peroxisomal protein import 0.3548949548650086 0.5638967577051204 0.5728243967597129 1.0 1.0 24 O75381,Q15067,O15254,Q13011 4 +Alpha oxidation of phytanate 0.4819832518431851 0.5607321758313039 0.5749801291449226 1.0 1.0 5 P51648 1 +Respiratory electron transport 0.3503404096319976 0.5605946824814263 0.5750738773442816 1.0 1.0 58 O75880,Q9NPL8,Q9UDW1,P22695,P00403,Q8N8Q8,P56556,P03886,O43674,O14949,O96000,P13073,P42704,O43676,Q86Y39 15 +Dna damage recognition in gg ner 0.3710516402165038 0.5451308178642397 0.5856635484913442 1.0 1.0 17 Q99627,P41208,Q9BT78 3 +Regulation of mecp2 expression and activity 0.4040497025911633 0.5418549148651978 0.5879184575432088 1.0 1.0 11 Q14739,P16220,P42858 3 +Lipophagy 0.5834813499111889 0.539187819627525 0.5897572640389825 1.0 1.0 3 P54619,P11142 2 +Mapk6 mapk4 signaling 0.356495657345294 0.5369607335602161 0.5912947376726021 1.0 1.0 49 P28072,P28070,O00231,Q99436,P51665,P28074,P20618,Q9UL46,P49721,P61289,Q06323 11 +Metabolism of steroids 0.3557670055953719 0.536527422891189 0.5915940885804805 1.0 1.0 50 P48449,Q16850,Q15125,P30536,Q9BWD1,Q9HCL2,O75845,Q14849,Q15800,Q15392,Q86X55,Q14739,P38435,Q15648 14 +Fcgr3a mediated il10 synthesis 0.4308874875923522 0.531525286560247 0.5950548233086845 1.0 1.0 8 O43865 1 +Tp53 regulates transcription of genes involved in g2 cell cycle arrest 0.4302020128247772 0.5283769001937582 0.5972377670951072 1.0 1.0 8 Q07812,Q86X55,P06493 3 +G2 phase 0.7090855282628035 0.5226485295115361 0.6012188624355013 1.0 1.0 2 P20248 1 +Ptk6 regulates cell cycle 0.7090855282628037 0.5226485295115361 0.6012188624355013 1.0 1.0 2 P11802 1 +Erk mapk targets 0.4195452384470255 0.5194530103980795 0.6034448728611395 1.0 1.0 9 P51812,P30154,P27361,Q15418 4 +Sphingolipid metabolism 0.3518689229378287 0.5132632220466133 0.6077672067940276 1.0 1.0 28 O95470,Q16739,Q06136,Q96G23 4 +Phospholipid metabolism 0.3545800061051316 0.5063879140963573 0.612584357291267 1.0 1.0 46 Q8N2A8,Q9NPH0,Q9HCL2,Q8TBX8,P43304,Q10713,Q9UG56,Q9HBU6,P35790,Q8IY17 10 +Metabolism of fat soluble vitamins 0.4330179111088411 0.5056277092820999 0.6131180256346023 1.0 1.0 7 Q8N0U8 1 +Cytosolic sulfonation of small molecules 0.4986111871913442 0.49475301740515 0.6207744723153961 1.0 1.0 4 Q9NX62 1 +Copi dependent golgi to er retrograde traffic 0.3486412145882769 0.4937499512757409 0.6214827831775649 1.0 1.0 53 Q9H0B6,P33176,O60333,O43731,Q9P2W9,Q15363,P49755,O15260,P24390 9 +Vitamin b2 riboflavin metabolism 0.6984314886061005 0.4894557423111744 0.6245190803808878 1.0 1.0 2 Q8NFF5 1 +Mitotic metaphase and anaphase 0.3036078475771599 0.4887197156149672 0.6250401437254225 1.0 1.0 141 O43633,Q12769,P28072,Q13409,P20700,P28074,P20618,Q92530,Q14997,Q9Y266,P61289,Q9UQE7,Q13200,P68371,P28070,P53990,Q8NFH4,P25787,Q9UJX3,P30154,Q8NBT2,Q96DE5,Q15005,P42167,Q8N1F7,Q14739,Q13257,Q06323,Q86XL3,Q9BTX1,Q86Y07,P51665,O43242,Q9UL46,P17980,Q9BUF5,P49721,Q92973,O00231,Q2NKX8,Q29RF7,Q8IXJ6,Q99436,P06493,P02545,Q8WUX9,P50402,Q9UJX4 48 +Signaling by erbb2 ecd mutants 0.4281402514546735 0.4845303268318306 0.6280095469013158 1.0 1.0 7 Q96RT1,P62993,P00533,Q16543 4 +Signaling by erbb2 in cancer 0.4281402514546735 0.4845303268318306 0.6280095469013158 1.0 1.0 7 Q96RT1,P62993,P00533,Q16543 4 +Rnd3 gtpase cycle 0.365893630508628 0.4748524216588356 0.6348921656089632 1.0 1.0 16 Q07065,P38159,Q9Y2I1,Q86UP2 4 +Biological oxidations 0.3517882894784953 0.4741251391028491 0.6354106727972422 1.0 1.0 42 P30837,Q16850,Q8TB61,Q9NX62,P78417,P07099,O43169,P21964,P16435,O00170,Q9NUJ1,Q8WUX2 12 +Conversion from apc c cdc20 to apc c cdh1 in late anaphase 0.409789994954578 0.4732318625108173 0.6360477680813301 1.0 1.0 9 Q9UJX4 1 +Apc c cdc20 mediated degradation of cyclin b 0.3909247979506792 0.4730607685171355 0.6361698250637382 1.0 1.0 11 Q96DE5,Q9UJX4,P06493 3 +Oncogenic mapk signaling 0.3423679850268981 0.4555692154994419 0.6486997843728695 1.0 1.0 26 Q6WCQ1,Q13555,Q9NRY5,Q53H12,Q99996,Q96PU8 6 +Tp53 regulates transcription of cell cycle genes 0.3494642263558477 0.4477349162256447 0.6543445193814086 1.0 1.0 18 P20248,Q9UKZ1,P06493,Q86X55,Q9Y3B8,Q07812,Q9UIV1,Q9NZN8 8 +Proton coupled monocarboxylate transport 0.6842261023971632 0.4466182973621548 0.6551506821541264 1.0 1.0 2 P35613 1 +G protein mediated events 0.385780740225166 0.446613405520856 0.6551542147909384 1.0 1.0 11 O43865,P16220 2 +Acyl chain remodelling of pg 0.6818585380290072 0.4396447662838688 0.6601944124640544 1.0 1.0 2 Q8NF37 1 +Separation of sister chromatids 0.2774061565678318 0.4301996502393278 0.6670504164109914 1.0 1.0 104 P28072,Q13409,P28074,P20618,Q9Y266,Q14997,P61289,Q9UQE7,Q13200,P28070,Q8NFH4,P25787,Q9UJX3,P30154,Q8NBT2,Q96DE5,Q15005,Q13257,Q06323,P51665,O43242,Q9UL46,P17980,P49721,O00231,Q2NKX8,Q29RF7,Q99436,Q9UJX4 29 +Transcriptional regulation by runx1 0.3177609353015458 0.4284343589534904 0.6683349140602237 1.0 1.0 70 P28072,P28070,O00231,Q9HCL2,Q99436,P51665,P28074,P20618,Q03164,P49721,P61289,Q06323 12 +Deadenylation dependent mrna decay 0.3453479716805918 0.4213193165561077 0.6735219267694483 1.0 1.0 42 P23588,P62310,Q5RKV6,Q9UK45,Q9H074,Q13868,Q14240,Q969T7,Q6PGP7 9 +Grb2 events in erbb2 signaling 0.6750517904705577 0.419871387924306 0.6745794106148548 1.0 1.0 2 P62993 1 +Pi3k events in erbb2 signaling 0.6750517904705577 0.419871387924306 0.6745794106148548 1.0 1.0 2 P62993 1 +Egfr transactivation by gastrin 0.6750517904705577 0.419871387924306 0.6745794106148548 1.0 1.0 2 P62993 1 +Senescence associated secretory phenotype sasp 0.3372995757536489 0.4143481635843961 0.6786191457297659 1.0 1.0 19 P20248,P51812,Q9UJX3,Q96DE5,Q15418,Q9UJX4,P27361,P11802 8 +G alpha i signalling events 0.3344875489532063 0.4137810680032818 0.6790344501301022 1.0 1.0 24 Q08209,P30154,Q13555,O43865,P16220 5 +Map3k8 tpl2 dependent mapk1 3 activation 0.4165023744455481 0.4102924942514628 0.6815913973570646 1.0 1.0 6 O15111,Q9Y297 2 +Heme biosynthesis 0.4400870086009275 0.4019292853829192 0.6877360694235595 1.0 1.0 5 P06132 1 +E3 ubiquitin ligases ubiquitinate target proteins 0.3538601493779583 0.4019067706568343 0.6877526396779616 1.0 1.0 16 Q5VTR2,O75381,O75150,Q14527 4 +Anti inflammatory response favouring leishmania parasite infection 0.3535842284651826 0.4002613946938035 0.688963999125215 1.0 1.0 16 O43865,P16220 2 +Negative feedback regulation of mapk pathway 0.5359670369216653 0.3895829896105103 0.6968449325665338 1.0 1.0 3 P27361 1 +Regulation of pten localization 0.6620301864456986 0.3832266665725634 0.701551707477202 1.0 1.0 2 Q93009 1 +Downregulation of erbb4 signaling 0.6620301864456987 0.3832266665725628 0.7015517074772024 1.0 1.0 2 Q96J02 1 +Leishmania infection 0.3400186097829769 0.378278334367956 0.7052238384245033 1.0 1.0 42 P09601,Q9UQB8,O43865,O14641,P35579,P16220,Q7L576 7 +Collagen biosynthesis and modifying enzymes 0.3623906050615517 0.3773498119686264 0.7059136589007116 1.0 1.0 12 P13674,P07237,Q32P28,O75718,Q8IVL6 5 +Abacavir transport and metabolism 0.656111275525308 0.3671048644489955 0.7135407989360831 1.0 1.0 2 P49902 1 +Nef mediated downregulation of mhc class i complex cell surface expression 0.4604678708913122 0.3660376395613218 0.7143369893417191 1.0 1.0 4 P04439,Q9BXS5,Q10567 3 +Pkmts methylate histone lysines 0.3593888065447796 0.3618055565417846 0.7174973395492028 1.0 1.0 12 Q03164 1 +Activated notch1 transmits signal to the nucleus 0.524866785079945 0.357564824087594 0.7206690064308492 1.0 1.0 3 P78536,Q96J02 2 +Gene and protein expression by jak stat signaling after interleukin 12 stimulation 0.3255894087686181 0.3426682278716132 0.7318480675846923 1.0 1.0 25 Q13126,P78417,Q9UL46,P52597,O14979,P14174 6 +Late endosomal microautophagy 0.3648530443118866 0.3426053907553754 0.7318953460341393 1.0 1.0 11 O43633,Q8WUX9,P08670,Q9H9H4 4 +Suppression of phagosomal maturation 0.3975930206470249 0.3381197911181499 0.7352729168055405 1.0 1.0 6 Q9UI12,Q14974,O14964 3 +Calnexin calreticulin cycle 0.3793391140608342 0.3359801214824208 0.7368858567770771 1.0 1.0 9 Q9UBV2 1 +Protein folding 0.3329399715741935 0.3300840155690342 0.7413364807211464 1.0 1.0 37 Q9UHV9,Q9Y2T2,O95302,P49368,O15212 5 +Sumo is conjugated to e1 uba2 sae1 0.5145056246299757 0.3288227832369006 0.7422896412930409 1.0 1.0 3 Q9UBE0,P61956 2 +Sumo is transferred from e1 to e2 ube2i ubc9 0.5145056246299757 0.3288227832369006 0.7422896412930409 1.0 1.0 3 Q9UBE0,P61956 2 +Processing and activation of sumo 0.5145056246299757 0.3288227832369006 0.7422896412930409 1.0 1.0 3 Q9UBE0,P61956 2 +Golgi to er retrograde transport 0.2909257342579434 0.323663001362034 0.746193184869768 1.0 1.0 78 Q9H0B6,Q10472,P33176,O60333,O43731,Q8TD16,Q15363,O75935,Q12981,P49755,Q9P2W9,O15260,P24390 13 +Endosomal vacuolar pathway 0.4447734675747561 0.3174932023037754 0.7508693966543722 1.0 1.0 4 P04439,P10321,Q9UIQ6 3 +Regulation of tp53 activity through acetylation 0.3433574839113533 0.3172660673568125 0.751041722657515 1.0 1.0 15 P31751 1 +Tp53 regulates transcription of genes involved in g1 cell cycle arrest 0.5034624028305126 0.299472549368527 0.7645795139244222 1.0 1.0 3 P20248 1 +Peptide hormone metabolism 0.3442271370232828 0.2929166298426027 0.7695858773186386 1.0 1.0 13 Q96A65,P67812,P33176,Q15005,Q8NEW0 5 +Uptake and function of anthrax toxins 0.4982238010657349 0.2860318581256154 0.7748537211777484 1.0 1.0 3 Q8WUM4,Q02750 2 +Signaling by activin 0.6226694288251016 0.2827728786802313 0.7773509458392995 1.0 1.0 2 P27361 1 +Signaling by nodal 0.6226694288251016 0.2827728786802313 0.7773509458392995 1.0 1.0 2 P27361 1 +Circadian clock 0.3414044060841448 0.2718957750886051 0.7857021598970366 1.0 1.0 12 Q9Y297,Q86X55,P43490,P16220 4 +Pre notch expression and processing 0.3497456393756111 0.2717787681103629 0.7857921315336416 1.0 1.0 11 P16615,Q9UBV2 2 +Condensation of prophase chromosomes 0.3554771346392183 0.264035534165439 0.7917525377168164 1.0 1.0 10 Q01105 1 +Negative regulation of flt3 0.6102397158922814 0.2545346857198494 0.7990825109168331 1.0 1.0 2 P41240 1 +Adp signalling through p2y purinoceptor 1 0.4804618117229324 0.2428762609374861 0.8081012560516838 1.0 1.0 3 P63218,Q9UBI6 2 +Activation of the ap 1 family of transcription factors 0.4804618117229231 0.2428762609374652 0.8081012560517 1.0 1.0 3 P28482,P27361 2 +Cdc6 association with the orc origin complex 0.3912544469794813 0.2412527481233196 0.8093592308654765 1.0 1.0 5 Q13416,Q9Y619 2 +Pyroptosis 0.357781740493922 0.226708505667859 0.8206504127498071 1.0 1.0 8 O43633,Q8WUX9 2 +Traf6 mediated nf kb activation 0.3862434895104253 0.2266308211723518 0.8207108239652232 1.0 1.0 5 O15111,Q14258,P09429 3 +Rhog gtpase cycle 0.3182362072226987 0.2221194540456345 0.8242208939667395 1.0 1.0 37 Q9NSV4,Q96RT1,Q7L576,Q86XL3,O15173,P49257,Q13190,P50402,Q86UP2,Q14739 10 +Triglyceride metabolism 0.3601926860698914 0.2203336522468919 0.8256113133669736 1.0 1.0 7 Q9HCL2 1 +Interleukin 12 signaling 0.3097218850505738 0.2196261759275192 0.8261623036667929 1.0 1.0 27 Q13126,P78417,Q9UL46,P52597,O14979,P14174 6 +Darpp 32 events 0.348634360554962 0.2115756921262589 0.8324380748816917 1.0 1.0 9 P30154 1 +Endosomal sorting complex required for transport escrt 0.3250046275187794 0.1994602720080332 0.8419027172607438 1.0 1.0 13 O43633,Q8WUX9,O14964,Q9BRG1 4 +Flt3 signaling in disease 0.3536633043469491 0.1986311434091588 0.8425512900833516 1.0 1.0 7 P62993,Q01082 2 +Small interfering rna sirna biogenesis 0.397690257625102 0.1908031001266563 0.8486798597590204 1.0 1.0 4 O75569,Q9UPY3,Q99598 3 +Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1 0.4501618013959781 0.1783579396427328 0.8584418789256125 1.0 1.0 3 P06493 1 +Deadenylation of mrna 0.3031537850973996 0.1678777592309532 0.8666794473546209 1.0 1.0 18 P23588,Q9UKZ1,Q9H074,Q14240,Q9UIV1,Q9NZN8 6 +Condensation of prometaphase chromosomes 0.3304623947522488 0.1635552060502645 0.8700813101263458 1.0 1.0 10 Q9BPX3,Q9NTJ3,Q15021,P06493 4 +Rho gtpases activate rocks 0.3243781217196025 0.162872495695532 0.8706188268856021 1.0 1.0 11 P35579,P35580,O75116,Q7Z406 4 +Transcriptional regulation by mecp2 0.3132400441268038 0.1620896629414706 0.8712352463304385 1.0 1.0 15 Q14739,P16220,P42858 3 +Rhod gtpase cycle 0.301814693642721 0.1615042649902895 0.8716962524784075 1.0 1.0 28 Q9NSV4,Q14739,O15173,Q86Y07,Q9Y6M7,Q9UEY8,P49257,P42167,P50402,P12814 10 +Prevention of phagosomal lysosomal fusion 0.4406023392599159 0.160484120106187 0.8724997298154882 1.0 1.0 3 O14964 1 +Glycogen storage diseases 0.4403693370418576 0.1600635713266765 0.8728309970032848 1.0 1.0 3 P13807 1 +Regulated necrosis 0.30153962304334 0.1591766069583481 0.8735297338075307 1.0 1.0 18 O43633,Q8WUX9,P09429,Q16543,O15294 5 +Constitutive signaling by ligand responsive egfr cancer variants 0.341045301150387 0.1589269031499185 0.8737264644239522 1.0 1.0 7 Q16543,P07900,P62993,P00533 4 +Signaling by egfr in cancer 0.341045301150387 0.1589269031499185 0.8737264644239522 1.0 1.0 7 Q16543,P07900,P62993,P00533 4 +Constitutive signaling by egfrviii 0.341045301150387 0.1589269031499185 0.8737264644239522 1.0 1.0 7 Q16543,P07900,P62993,P00533 4 +Activation of ampk downstream of nmdars 0.3408417308832268 0.1583113479977067 0.8742114664971772 1.0 1.0 7 P68371,Q13509,Q13885,Q13131,P54619,Q9BUF5 6 +Interleukin 12 family signaling 0.3017737863382401 0.1541991777500261 0.8774526904974667 1.0 1.0 29 Q13126,P78417,Q9UL46,P52597,O14979,P14174 6 +Response of eif2ak1 hri to heme deficiency 0.4325044404973436 0.1462909421890565 0.8836917160196005 1.0 1.0 3 P05198,P20042 2 +Ca dependent events 0.3323482362468415 0.1406620825933922 0.8881369009075779 1.0 1.0 8 P16220 1 +Signaling by ntrk3 trkc 0.3517583117808727 0.1369696622640119 0.8910547750737456 1.0 1.0 5 P62993 1 +E2f mediated regulation of dna replication 0.311331836910418 0.1365492188049035 0.8913871179105592 1.0 1.0 12 Q9Y619,P30154,P06493,Q13416,P30153 5 +Non integrin membrane ecm interactions 0.3321704734566867 0.1295757502324281 0.8969020899827438 1.0 1.0 6 P07942 1 +Runx2 regulates bone development 0.3480450236966783 0.1285164678219819 0.8977402668515446 1.0 1.0 5 Q9UPW6,P28482,P27361,Q96PK6 4 +Transport of connexons to the plasma membrane 0.3480208043137612 0.1284621256644906 0.8977832691774181 1.0 1.0 5 Q9BUF5 1 +Gap junction assembly 0.3480208043137612 0.1284621256644906 0.8977832691774181 1.0 1.0 5 Q9BUF5 1 +Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components 0.308128339341022 0.1234348941194369 0.9017627268282632 1.0 1.0 12 Q96DE5,Q13257,Q9UJX4 3 +Apc cdc20 mediated degradation of nek2a 0.308128339341022 0.1234348941194369 0.9017627268282632 1.0 1.0 12 Q96DE5,Q13257,Q9UJX4 3 +Signaling by moderate kinase activity braf mutants 0.3057287028791953 0.1137923268164247 0.9094024213961158 1.0 1.0 12 P46940,P35232,Q13555,Q9Y490,P27448,P18206,P41240,P31946,P28482,P27361,Q02750 11 +Map2k and mapk activation 0.3057287028791943 0.1137923268164205 0.9094024213961192 1.0 1.0 12 Q9Y2Q5,P46940,Q9UHA4,Q9Y490,P27448,P18206,P41240,P31946,P28482,P27361,Q02750 11 +Cytokine signaling in immune system 0.2967625506058178 0.1136074469700231 0.9095489837481368 1.0 1.0 179 P28072,P31751,P28074,P20618,O00170,Q14997,Q9Y297,P61289,P28070,Q07820,Q9H3S7,P31749,P30154,P78417,Q13277,Q99567,P19474,Q8N1F7,O14979,Q06323,Q13501,Q9BTX1,P09601,Q9Y3Z3,P12270,Q13126,P51665,P08670,Q9UL46,P16220,P49721,P14174,O00231,Q99436,P52597,P09429,Q14240,Q15418 38 +Cyclin a b1 b2 associated events during g2 m transition 0.3053916928161468 0.112450692110466 0.9104660636806404 1.0 1.0 12 P30153,P30154,P20248,P06493 4 +Cytosolic iron sulfur cluster assembly 0.3253333333333371 0.1121950341959227 0.9106687664491304 1.0 1.0 6 P28340,Q6FI81,Q9Y5Y2,P18074,O75027 5 +Regulated proteolysis of p75ntr 0.524711453092638 0.1095105212597363 0.912797577200952 1.0 1.0 2 P78536 1 +Notch4 activation and transmission of signal to the nucleus 0.524711453092638 0.1095105212597363 0.912797577200952 1.0 1.0 2 P63104 1 +Diseases of mitotic cell cycle 0.3033627163758578 0.1088063896399792 0.91335605571185 1.0 1.0 14 Q96DE5,Q9UJX3,P11802,Q9UJX4 4 +Atf4 activates genes in response to endoplasmic reticulum stress 0.3036857137549935 0.1062937482649904 0.9153492916529676 1.0 1.0 13 Q13868 1 +Esr mediated signaling 0.3033964597137178 0.0996599854904421 0.920614269281452 1.0 1.0 48 P35269,P31749,Q9HCL2,P31751,O43815,P16220,Q86X55 7 +Nuclear envelope ne reassembly 0.3013002682800357 0.0927580487615713 0.9260957795033996 1.0 1.0 53 Q12769,O43633,P20700,P68371,P53990,Q8NFH4,Q9BVL2,P42167,Q8N1F7,Q14739,Q9BTX1,Q86XL3,Q86Y07,Q9BUF5,Q92973,Q8IXJ6,P06493,P02545,Q8WUX9,P50402 20 +Runx2 regulates osteoblast differentiation 0.3479419603198037 0.092466364614607 0.9263275138509128 1.0 1.0 4 Q9UPW6,P28482,P27361 3 +Ovarian tumor domain proteases 0.3133150811638905 0.0913580321763557 0.9272081077166784 1.0 1.0 9 P25054,P06493,Q6GQQ9 3 +Myd88 independent tlr4 cascade 0.280419944205518 0.0850362507736688 0.9322325711217244 1.0 1.0 22 P51812,P30154,P09429,P16220,O15111,Q9Y297,Q15418,P27361,P30153 9 +Inla mediated entry of listeria monocytogenes into host cells 0.4998520272269969 0.0832023909112307 0.9336906116613868 1.0 1.0 2 P35222 1 +Erks are inactivated 0.3123553845245977 0.0817593627419699 0.9348380716735752 1.0 1.0 6 P30154,P27361 2 +Response to elevated platelet cytosolic ca2 0.2947420572546919 0.0800760782251749 0.9361767484497264 1.0 1.0 34 P35609,Q9NUQ9,P10909,Q9BWS9,O94919,O43852,P12814 7 +Phenylalanine and tyrosine metabolism 0.3842435438079825 0.0795129474479434 0.936624633645272 1.0 1.0 3 P16930 1 +Inositol phosphate metabolism 0.3381699733491218 0.0776732160756511 0.938088000196905 1.0 1.0 4 P19174,Q01968,Q9NPH2 3 +Cargo trafficking to the periciliary membrane 0.2767775373719422 0.0745080915047308 0.9406061029753467 1.0 1.0 21 P49368,P78371,A6NIH7,Q96A65 4 +Egfr interacts with phospholipase c gamma 0.4886060964782558 0.0734074245304627 0.9414819096166342 1.0 1.0 2 P00533 1 +Activation of smo 0.4883101509322363 0.0731663697538375 0.9416737276839744 1.0 1.0 2 Q9Y496 1 +Dap12 interactions 0.3081481481481513 0.0726210999403499 0.9421076357271292 1.0 1.0 6 P19174,P10321,P01889,P63000,P62993 5 +Tak1 activates nfkb by phosphorylation and activation of ikks complex 0.3183365770225223 0.0696761961112626 0.9444513884762322 1.0 1.0 5 O15111,P09429 2 +Plasma lipoprotein assembly 0.3743965753337938 0.0694708715189888 0.9446148177811762 1.0 1.0 3 P07237 1 +Activation of ppargc1a pgc 1alpha by phosphorylation 0.480319621189708 0.0669700078847996 0.946605579820301 1.0 1.0 2 P54619 1 +Signal attenuation 0.3291470986751246 0.0653063900885358 0.9479300546529216 1.0 1.0 4 P62993 1 +Egfr downregulation 0.3013942450311594 0.0644978036835726 0.9485738558789 1.0 1.0 10 P22681,O14964,P00533,Q9Y6I3,Q92783,Q9UBC2,P42566,P62993,P60953 9 +Glutathione synthesis and recycling 0.3265500091942187 0.0619725870844662 0.9505846623653283 1.0 1.0 4 Q8WUX2 1 +Activation of the pre replicative complex 0.2785487505963814 0.0576313847471559 0.9540422497982666 1.0 1.0 24 P33991,Q9Y619,P25205,O75419,P33993,Q14566,Q9NR33,Q9UBD5,P24941,Q13416 10 +Maturation of sars cov 1 spike protein 0.3221794492152673 0.0565861866188014 0.9548748383946076 1.0 1.0 4 P14314,P27824,Q13724 3 +Thrombin signalling through proteinase activated receptors pars 0.3089454976303198 0.0543341446439012 0.9566689462300024 1.0 1.0 5 P63218,Q9UBI6,P27361,P28482 4 +Class b 2 secretin family receptors 0.3519834221432766 0.0506901277989613 0.9595724434123836 1.0 1.0 3 P63218,Q9UBI6 2 +Energy dependent regulation of mtor by lkb1 ampk 0.2966635845798257 0.0503885188092376 0.9598127854281132 1.0 1.0 10 P49815,Q9UHA4,Q15382 3 +Mrna decay by 5 to 3 exoribonuclease 0.298296662035422 0.0489377444249934 0.9609689091825444 1.0 1.0 9 P62310 1 +Activation of atr in response to replication stress 0.271848193656129 0.0488590499021452 0.9610316233060884 1.0 1.0 21 P33991,Q9Y619,P25205,O75419,P33993,Q14566,Q9UBD5,P24941,P40937,Q13416 10 +Diseases of mismatch repair mmr 0.3472468916518666 0.0473956159747511 0.9621979230409584 1.0 1.0 3 P43246,P52701 2 +Erbb2 regulates cell motility 0.3436944937833046 0.0450685620899766 0.9640526597674304 1.0 1.0 3 P00533,O60610 2 +Rho gtpases activate paks 0.2876162437031003 0.0445943814571696 0.9644306211540296 1.0 1.0 13 P35579,P35580,Q7Z406 3 +Gap junction trafficking and regulation 0.2913946587537183 0.0443718561501356 0.964607995084551 1.0 1.0 11 P68371,Q00610,Q9UM54,Q13885,Q13509,P09496,Q07157,Q9BVA1,P50570,Q9BUF5 10 +Neurotransmitter receptors and postsynaptic signal transmission 0.291242795638327 0.0440975481799627 0.964826647154271 1.0 1.0 37 P68371,P35609,Q12959,Q14168,P07196,P51812,Q9UBI6,Q13555,O14936,P16220,Q9BUF5,P27361,Q15418 13 +Golgi cisternae pericentriolar stack reorganization 0.2863865596119893 0.042044518132903 0.9664632091358614 1.0 1.0 12 Q08379,O60763 2 +Basigin interactions 0.2924444444444474 0.0416844864021331 0.9667502212694798 1.0 1.0 6 P05026,P35613,P53985,P05556,P08195 5 +Dap12 signaling 0.3079656499851906 0.0409570398324302 0.9673301443501738 1.0 1.0 4 P19174,P62993,P63000 3 +Signalling to ras 0.30796564998519 0.0409570398324297 0.9673301443501744 1.0 1.0 4 P62993,P11233,Q16539 3 +Chl1 interactions 0.3365896980461754 0.040769709080825 0.9674794879242612 1.0 1.0 3 P11142,P05556 2 +Rna polymerase iii chain elongation 0.2918518518518549 0.0406148305966717 0.9676029608061604 1.0 1.0 6 O14802,O15160,Q9BUI4,P19388,Q9H1D9 5 +Rna polymerase iii transcription initiation from type 3 promoter 0.2918518518518549 0.0406148305966717 0.9676029608061604 1.0 1.0 6 O14802,O15160,Q9BUI4,P19388,Q9H1D9 5 +Molecules associated with elastic fibres 0.4158034921574522 0.0355195480244344 0.9716654591401356 1.0 1.0 2 P55081 1 +Elastic fibre formation 0.4158034921574522 0.0355195480244344 0.9716654591401356 1.0 1.0 2 P55081 1 +Rna polymerase iii transcription termination 0.2919383521043293 0.0352983426539907 0.971841844879314 1.0 1.0 7 P05455,O14802,O15160,Q9BUI4,P19388,Q9H1D9 6 +Tgf beta receptor signaling in emt epithelial to mesenchymal transition 0.2989591384646093 0.0324834462035963 0.9740865170793708 1.0 1.0 4 P62942 1 +Perk regulates gene expression 0.2829922207986891 0.0319210859000849 0.9745349830904786 1.0 1.0 15 Q13868 1 +Activation of nima kinases nek9 nek6 nek7 0.2926540284360152 0.0313374906619579 0.9750003918556748 1.0 1.0 5 O95067,Q8TD19,P14635,P06493 4 +Activated ntrk2 signals through cdk5 0.3968629772122024 0.0310290438755526 0.9752463771567428 1.0 1.0 2 Q00535 1 +Nef and signal transduction 0.3968629772121996 0.031029043875552 0.9752463771567432 1.0 1.0 2 Q13177 1 +Activation of rac1 downstream of nmdars 0.3968629772121996 0.031029043875552 0.9752463771567432 1.0 1.0 2 Q14012 1 +Gap junction degradation 0.290876777251179 0.0290989789686319 0.9767856501193848 1.0 1.0 5 Q00610,Q9UM54,P09496,P50570 4 +Synthesis of ip2 ip and ins in the cytosol 0.3841373187333612 0.0288236000457387 0.977005278582944 1.0 1.0 2 Q9NPH2 1 +Shc1 events in egfr signaling 0.3103146254441948 0.0285627817139196 0.9772132958546332 1.0 1.0 3 P62993 1 +Thromboxane signalling through tp receptor 0.3087625814091111 0.0280032822485816 0.9776595333189436 1.0 1.0 3 P63218,Q9UBI6 2 +G2 m dna replication checkpoint 0.2934557299378066 0.0278219074849213 0.9778041930782652 1.0 1.0 4 O95067,Q99640,P06493 3 +Tfap2 ap 2 family regulates transcription of growth factors and their receptors 0.336786031370236 0.0244604786970526 0.9804853077060888 1.0 1.0 2 P00533 1 +Translation of replicase and assembly of the replication transcription complex 0.2822401231403688 0.0242476545353273 0.9806550664674032 1.0 1.0 6 O43633 1 +Fbxw7 mutants and notch1 in cancer 0.3074874223143025 0.0235151579655002 0.9812393475204504 1.0 1.0 2 P63208 1 +Complex i biogenesis 0.2829369048323782 0.0231670540448809 0.9815170186139532 1.0 1.0 32 Q9NPL8,O43674,P56556,P03886,O96000,O43676,Q86Y39 7 +Synthesis of leukotrienes lt and eoxins ex 0.2785671995263411 0.0199609232403713 0.984074545086438 1.0 1.0 3 P09960,Q14914 2 +Nuclear receptor transcription pathway 0.2782711663706287 0.0199051235322696 0.9841190579680958 1.0 1.0 3 Q15648,Q9UHY1 2 +Establishment of sister chromatid cohesion 0.286476868327404 0.019470472300629 0.9844657922671802 1.0 1.0 9 Q96FF9,Q8N3U4,Q7Z5K2,O60216,Q29RF7,Q14683,Q9UQE7,Q8WVM7 8 +Rhoa gtpase cycle 0.2914829017918696 0.0189652150073254 0.9848688548189388 1.0 1.0 46 Q9NSV4,Q96RT1,Q9UDY2,O75116,O15173,P30519,Q92888,Q07021,Q92974,Q16513,P49257,Q13190,P42167,Q86UP2,Q14739,Q15904,Q96HY6 17 +Nr1h2 and nr1h3 mediated signaling 0.2785185185185216 0.0184024435319584 0.9853178031169668 1.0 1.0 6 Q8NB78,Q9HCE1,P49327,O60341,O00767 5 +Hiv transcription initiation 0.2776080112979222 0.0174566677625948 0.9860723016895224 1.0 1.0 16 Q92804,Q15545,O00268,P29083,P18074,P19388,P35269 7 +G1 s specific transcription 0.2823287934221794 0.0170274738558612 0.9864146979795592 1.0 1.0 11 O75419,P00374,P31350 3 +Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux 0.2783535682558427 0.0169052000881524 0.98651224429026 1.0 1.0 4 Q9HCE1,Q8NB78,O60341 3 +Mapk3 erk1 activation 0.2755348833786771 0.0151532194394568 0.9879099428511768 1.0 1.0 4 P06493 1 +Syndecan interactions 0.2723747627840523 0.0132891603806838 0.989397096189092 1.0 1.0 4 P12814 1 +Negative regulation of fgfr1 signaling 0.2749347863203574 0.0130294100524291 0.9896043290213884 1.0 1.0 6 P62993,P27361 2 +Spry regulation of fgf signaling 0.2749347863203574 0.0130294100524291 0.9896043290213884 1.0 1.0 6 P62993,P27361 2 +Negative regulation of fgfr4 signaling 0.2749347863203574 0.0130294100524291 0.9896043290213884 1.0 1.0 6 P62993,P27361 2 +Negative regulation of fgfr3 signaling 0.2749347863203574 0.0130294100524291 0.9896043290213884 1.0 1.0 6 P62993,P27361 2 +Negative regulation of fgfr2 signaling 0.2749347863203574 0.0130294100524291 0.9896043290213884 1.0 1.0 6 P62993,P27361 2 +Met activates ras signaling 0.2748303097662921 0.0111795445572185 0.991080199804108 1.0 1.0 5 Q96P70 1 +Rac3 gtpase cycle 0.2837944359955223 0.0107168985994282 0.9914493157452172 1.0 1.0 35 Q9NSV4,O15173,Q9UQB8,P50402,Q9H2K8,Q7L576 6 +Attachment of gpi anchor to upar 0.2540716612377814 0.0044082915755512 0.9964827036043112 1.0 1.0 4 Q92643,Q96S52,O43292 3 +G beta gamma signalling through cdc42 0.2416345869114535 7.3543871181540206e-06 0.9999941320480644 1.0 1.0 4 P63218,Q9UBI6,P60953 3 diff --git a/msigdb_reactome/selections.json b/msigdb_reactome/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..beeae599409040cba52f9a6f0b7ca9358491bb28 --- /dev/null +++ b/msigdb_reactome/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2 ltr circle formation", "Abacavir metabolism", "Abacavir transmembrane transport", "Abacavir transport and metabolism", "Abc family proteins mediated transport", "Abc transporter disorders", "Abc transporters in lipid homeostasis", "Aberrant regulation of mitotic exit in cancer due to rb1 defects", "Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects", "Abortive elongation of hiv 1 transcript in the absence of tat", "Acetylcholine regulates insulin secretion", "Activated notch1 transmits signal to the nucleus", "Activated ntrk2 signals through cdk5", "Activated ntrk2 signals through frs2 and frs3", "Activated ntrk2 signals through fyn", "Activated ntrk2 signals through pi3k", "Activated ntrk2 signals through ras", "Activated ntrk3 signals through ras", "Activated pkn1 stimulates transcription of ar androgen receptor regulated genes klk2 and klk3", "Activated tak1 mediates p38 mapk activation", "Activation of ampk downstream of nmdars", "Activation of anterior hox genes in hindbrain development during early embryogenesis", "Activation of atr in response to replication stress", "Activation of bad and translocation to mitochondria", "Activation of bh3 only proteins", "Activation of gene expression by srebf srebp", "Activation of irf3 irf7 mediated by tbk1 ikk epsilon", "Activation of kainate receptors upon glutamate binding", "Activation of nima kinases nek9 nek6 nek7", "Activation of nmda receptors and postsynaptic events", "Activation of noxa and translocation to mitochondria", "Activation of ppargc1a pgc 1alpha by phosphorylation", "Activation of puma and translocation to mitochondria", "Activation of rac1", "Activation of rac1 downstream of nmdars", "Activation of smo", "Activation of the ap 1 family of transcription factors", "Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s", "Activation of the pre replicative complex", "Activation of the tfap2 ap 2 family of transcription factors", "Acyl chain remodeling of cl", "Acyl chain remodelling of pc", "Acyl chain remodelling of pg", "Acyl chain remodelling of pi", "Acyl chain remodelling of ps", "Adaptive immune system", "Adenylate cyclase inhibitory pathway", "Adherens junctions interactions", "Adora2b mediated anti inflammatory cytokines production", "Adp signalling through p2y purinoceptor 1", "Adp signalling through p2y purinoceptor 12", "Adrenaline noradrenaline inhibits insulin secretion", "Advanced glycosylation endproduct receptor signaling", "Aflatoxin activation and detoxification", "Aggrephagy", "Akt phosphorylates targets in the cytosol", "Akt phosphorylates targets in the nucleus", "Alk mutants bind tkis", "Alpha linolenic omega3 and linoleic omega6 acid metabolism", "Alpha oxidation of phytanate", "Alpha protein kinase 1 signaling pathway", "Amino acid transport across the plasma membrane", "Amino acids regulate mtorc1", "Amyloid fiber formation", "Anchoring of the basal body to the plasma membrane", "Androgen biosynthesis", "Anti inflammatory response favouring leishmania parasite infection", "Antigen activates b cell receptor bcr leading to generation of second messengers", "Antigen presentation folding assembly and peptide loading of class i mhc", "Antigen processing cross presentation", "Antigen processing ubiquitination proteasome degradation", "Antimicrobial peptides", "Antiviral mechanism by ifn stimulated genes", "Apc c cdc20 mediated degradation of cyclin b", "Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1", "Apc c mediated degradation of cell cycle proteins", "Apc cdc20 mediated degradation of nek2a", "Apex1 independent resolution of ap sites via the single nucleotide replacement pathway", "Apobec3g mediated resistance to hiv 1 infection", "Apoptosis", "Apoptosis induced dna fragmentation", "Apoptotic cleavage of cell adhesion proteins", "Apoptotic cleavage of cellular proteins", "Apoptotic execution phase", "Apoptotic factor mediated response", "Aquaporin mediated transport", "Arachidonate production from dag", "Arachidonic acid metabolism", "Arms mediated activation", "Aryl hydrocarbon receptor signalling", "Asparagine n linked glycosylation", "Aspartate and asparagine metabolism", "Assembly and cell surface presentation of nmda receptors", "Assembly of active lpl and lipc lipase complexes", "Assembly of collagen fibrils and other multimeric structures", "Assembly of the hiv virion", "Assembly of the orc complex at the origin of replication", "Association of tric cct with target proteins during biosynthesis", "Asymmetric localization of pcp proteins", "Atf4 activates genes in response to endoplasmic reticulum stress", "Atf6 atf6 alpha activates chaperone genes", "Atf6 atf6 alpha activates chaperones", "Attachment and entry", "Attachment of gpi anchor to upar", "Attenuation phase", "Auf1 hnrnp d0 binds and destabilizes mrna", "Aurka activation by tpx2", "Autophagy", "B wich complex positively regulates rrna expression", "Base excision repair", "Base excision repair ap site formation", "Basigin interactions", "Bbsome mediated cargo targeting to cilium", "Beta catenin independent wnt signaling", "Beta catenin phosphorylation cascade", "Beta oxidation of butanoyl coa to acetyl coa", "Beta oxidation of decanoyl coa to octanoyl coa coa", "Beta oxidation of hexanoyl coa to butanoyl coa", "Beta oxidation of lauroyl coa to decanoyl coa coa", "Beta oxidation of octanoyl coa to hexanoyl coa", "Beta oxidation of pristanoyl coa", "Beta oxidation of very long chain fatty acids", "Bicarbonate transporters", "Bile acid and bile salt metabolism", "Binding and uptake of ligands by scavenger receptors", "Binding of tcf lef ctnnb1 to target gene promoters", "Biological oxidations", "Biosynthesis of epa derived spms", "Biosynthesis of specialized proresolving mediators spms", "Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein", "Biotin transport and metabolism", "Bmal1 clock npas2 activates circadian gene expression", "Branched chain amino acid catabolism", "Budding and maturation of hiv virion", "Butyrate response factor 1 brf1 binds and destabilizes mrna", "C type lectin receptors clrs", "Ca dependent events", "Ca2 pathway", "Calcineurin activates nfat", "Calnexin calreticulin cycle", "Camk iv mediated phosphorylation of creb", "Carboxyterminal post translational modifications of tubulin", "Cardiac conduction", "Cargo concentration in the er", "Cargo recognition for clathrin mediated endocytosis", "Cargo trafficking to the periciliary membrane", "Carnitine metabolism", "Caspase activation via death receptors in the presence of ligand", "Caspase activation via dependence receptors in the absence of ligand", "Caspase activation via extrinsic apoptotic signalling pathway", "Caspase mediated cleavage of cytoskeletal proteins", "Cation coupled chloride cotransporters", "Cd163 mediating an anti inflammatory response", "Cd209 dc sign signaling", "Cd22 mediated bcr regulation", "Cd28 co stimulation", "Cd28 dependent pi3k akt signaling", "Cd28 dependent vav1 pathway", "Cdc42 gtpase cycle", "Cdc6 association with the orc origin complex", "Cdt1 association with the cdc6 orc origin complex", "Cell cell communication", "Cell cell junction organization", "Cell cycle", "Cell cycle checkpoints", "Cell cycle mitotic", "Cell death signalling via nrage nrif and nade", "Cell extracellular matrix interactions", "Cell junction organization", "Cell surface interactions at the vascular wall", "Cellular response to chemical stress", "Cellular response to heat stress", "Cellular response to hypoxia", "Cellular response to starvation", "Cellular responses to stimuli", "Cellular senescence", "Chaperone mediated autophagy", "Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex", "Chl1 interactions", "Cholesterol biosynthesis", "Choline catabolism", "Chondroitin sulfate dermatan sulfate metabolism", "Chrebp activates metabolic gene expression", "Chromatin modifying enzymes", "Chromosome maintenance", "Chylomicron assembly", "Chylomicron clearance", "Cilium assembly", "Circadian clock", "Citric acid cycle tca cycle", "Class a 1 rhodopsin like receptors", "Class b 2 secretin family receptors", "Class i mhc mediated antigen processing presentation", "Class i peroxisomal membrane protein import", "Clathrin mediated endocytosis", "Clec7a dectin 1 induces nfat activation", "Clec7a dectin 1 signaling", "Cobalamin cbl vitamin b12 transport and metabolism", "Coenzyme a biosynthesis", "Cohesin loading onto chromatin", "Collagen biosynthesis and modifying enzymes", "Collagen degradation", "Collagen formation", "Competing endogenous rnas cernas regulate pten translation", "Complement cascade", "Complex i biogenesis", "Condensation of prometaphase chromosomes", "Condensation of prophase chromosomes", "Constitutive signaling by aberrant pi3k in cancer", "Constitutive signaling by akt1 e17k in cancer", "Constitutive signaling by egfrviii", "Constitutive signaling by ligand responsive egfr cancer variants", "Constitutive signaling by overexpressed erbb2", "Conversion from apc c cdc20 to apc c cdh1 in late anaphase", "Cooperation of pdcl phlp1 and tric cct in g protein beta folding", "Cooperation of prefoldin and tric cct in actin and tubulin folding", "Copi dependent golgi to er retrograde traffic", "Copi independent golgi to er retrograde traffic", "Copi mediated anterograde transport", "Copii mediated vesicle transport", "Costimulation by the cd28 family", "Creatine metabolism", "Creb phosphorylation", "Creb1 phosphorylation through nmda receptor mediated activation of ras signaling", "Creb1 phosphorylation through the activation of adenylate cyclase", "Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde", "Cristae formation", "Crmps in sema3a signaling", "Cross presentation of soluble exogenous antigens endosomes", "Cs ds degradation", "Ctla4 inhibitory signaling", "Cyclin a b1 b2 associated events during g2 m transition", "Cyclin a cdk2 associated events at s phase entry", "Cyclin d associated events in g1", "Cytochrome c mediated apoptotic response", "Cytochrome p450 arranged by substrate type", "Cytokine signaling in immune system", "Cytoprotection by hmox1", "Cytosolic iron sulfur cluster assembly", "Cytosolic sensors of pathogen associated dna", "Cytosolic sulfonation of small molecules", "Cytosolic trna aminoacylation", "Dag and ip3 signaling", "Dap12 interactions", "Dap12 signaling", "Darpp 32 events", "Dcc mediated attractive signaling", "Ddx58 ifih1 mediated induction of interferon alpha beta", "Deactivation of the beta catenin transactivating complex", "Deadenylation dependent mrna decay", "Deadenylation of mrna", "Death receptor signalling", "Dectin 1 mediated noncanonical nf kb signaling", "Dectin 2 family", "Defective cftr causes cystic fibrosis", "Defective chst14 causes eds musculocontractural type", "Defective factor ix causes hemophilia b", "Defective intrinsic pathway for apoptosis", "Defects in biotin btn metabolism", "Defects in cobalamin b12 metabolism", "Defects in vitamin and cofactor metabolism", "Defects of contact activation system cas and kallikrein kinin system kks", "Degradation of axin", "Degradation of beta catenin by the destruction complex", "Degradation of cysteine and homocysteine", "Degradation of dvl", "Degradation of gli1 by the proteasome", "Degradation of the extracellular matrix", "Depolymerisation of the nuclear lamina", "Deposition of new cenpa containing nucleosomes at the centromere", "Dermatan sulfate biosynthesis", "Detoxification of reactive oxygen species", "Deubiquitination", "Developmental biology", "Dex h box helicases activate type i ifn and inflammatory cytokines production", "Digestion", "Digestion and absorption", "Disassembly of the destruction complex and recruitment of axin to the membrane", "Diseases associated with glycosaminoglycan metabolism", "Diseases associated with glycosylation precursor biosynthesis", "Diseases associated with n glycosylation of proteins", "Diseases associated with o glycosylation of proteins", "Diseases of base excision repair", "Diseases of carbohydrate metabolism", "Diseases of dna repair", "Diseases of glycosylation", "Diseases of immune system", "Diseases of metabolism", "Diseases of mismatch repair mmr", "Diseases of mitotic cell cycle", "Diseases of programmed cell death", "Diseases of signal transduction by growth factor receptors and second messengers", "Disinhibition of snare formation", "Disorders of transmembrane transporters", "Displacement of dna glycosylase by apex1", "Dissolution of fibrin clot", "Dna damage bypass", "Dna damage recognition in gg ner", "Dna damage reversal", "Dna damage telomere stress induced senescence", "Dna double strand break repair", "Dna double strand break response", "Dna methylation", "Dna repair", "Dna replication", "Dna replication initiation", "Dna replication pre initiation", "Dna strand elongation", "Dopamine clearance from the synaptic cleft", "Dopamine neurotransmitter release cycle", "Downregulation of erbb2 erbb3 signaling", "Downregulation of erbb2 signaling", "Downregulation of erbb4 signaling", "Downregulation of smad2 3 smad4 transcriptional activity", "Downregulation of tgf beta receptor signaling", "Downstream signal transduction", "Downstream signaling events of b cell receptor bcr", "Downstream signaling of activated fgfr1", "Downstream signaling of activated fgfr2", "Downstream signaling of activated fgfr3", "Downstream signaling of activated fgfr4", "Dscam interactions", "Dual incision in gg ner", "Dual incision in tc ner", "E2f enabled inhibition of pre replication complex formation", "E2f mediated regulation of dna replication", "E3 ubiquitin ligases ubiquitinate target proteins", "Early phase of hiv life cycle", "Ecm proteoglycans", "Effects of pip2 hydrolysis", "Egfr downregulation", "Egfr interacts with phospholipase c gamma", "Egfr transactivation by gastrin", "Egr2 and sox10 mediated initiation of schwann cell myelination", "Elastic fibre formation", "Endogenous sterols", "Endosomal sorting complex required for transport escrt", "Endosomal vacuolar pathway", "Energy dependent regulation of mtor by lkb1 ampk", "Enos activation", "Eph ephrin mediated repulsion of cells", "Eph ephrin signaling", "Epha mediated growth cone collapse", "Ephb mediated forward signaling", "Ephrin signaling", "Epigenetic regulation of gene expression", "Er quality control compartment erqc", "Er to golgi anterograde transport", "Erbb2 activates ptk6 signaling", "Erbb2 regulates cell motility", "Ercc6 csb and ehmt2 g9a positively regulate rrna expression", "Erk mapk targets", "Erks are inactivated", "Erythropoietin activates phosphoinositide 3 kinase pi3k", "Erythropoietin activates phospholipase c gamma plcg", "Erythropoietin activates ras", "Erythropoietin activates stat5", "Esr mediated signaling", "Establishment of sister chromatid cohesion", "Estrogen biosynthesis", "Estrogen dependent gene expression", "Estrogen dependent nuclear events downstream of esr membrane signaling", "Estrogen stimulated signaling through prkcz", "Ethanol oxidation", "Eukaryotic translation elongation", "Eukaryotic translation initiation", "Export of viral ribonucleoproteins from nucleus", "Extension of telomeres", "Extra nuclear estrogen signaling", "Extracellular matrix organization", "Factors involved in megakaryocyte development and platelet production", "Fanconi anemia pathway", "Fasl cd95l signaling", "Fatty acid metabolism", "Fatty acyl coa biosynthesis", "Fbxw7 mutants and notch1 in cancer", "Fc epsilon receptor fceri signaling", "Fceri mediated ca 2 mobilization", "Fceri mediated mapk activation", "Fceri mediated nf kb activation", "Fcgamma receptor fcgr dependent phagocytosis", "Fcgr activation", "Fcgr3a mediated il10 synthesis", "Fgfr1 mutant receptor activation", "Fgfr2 alternative splicing", "Fgfr2 mutant receptor activation", "Fibronectin matrix formation", "Flt3 signaling", "Flt3 signaling by cbl mutants", "Flt3 signaling in disease", "Folding of actin by cct tric", "Formation of apoptosome", "Formation of atp by chemiosmotic coupling", "Formation of fibrin clot clotting cascade", "Formation of incision complex in gg ner", "Formation of rna pol ii elongation complex", "Formation of senescence associated heterochromatin foci sahf", "Formation of tc ner pre incision complex", "Formation of the beta catenin tcf transactivating complex", "Formation of the cornified envelope", "Formation of the early elongation complex", "Formation of tubulin folding intermediates by cct tric", "Formation of xylulose 5 phosphate", "Formyl peptide receptors bind formyl peptides and many other ligands", "Foxo mediated transcription", "Foxo mediated transcription of oxidative stress metabolic and neuronal genes", "Free fatty acids regulate insulin secretion", "Frs mediated fgfr1 signaling", "Frs mediated fgfr2 signaling", "Frs mediated fgfr3 signaling", "Frs mediated fgfr4 signaling", "Fructose metabolism", "G alpha 12 13 signalling events", "G alpha i signalling events", "G alpha q signalling events", "G alpha s signalling events", "G alpha z signalling events", "G beta gamma signalling through cdc42", "G beta gamma signalling through pi3kgamma", "G protein activation", "G protein beta gamma signalling", "G protein mediated events", "G0 and early g1", "G1 s dna damage checkpoints", "G1 s specific transcription", "G2 m checkpoints", "G2 m dna damage checkpoint", "G2 m dna replication checkpoint", "G2 phase", "Gab1 signalosome", "Gaba b receptor activation", "Gaba receptor activation", "Gaba synthesis release reuptake and degradation", "Galactose catabolism", "Gamma carboxylation hypusine formation and arylsulfatase activation", "Gamma carboxylation transport and amino terminal cleavage of proteins", "Gap filling dna repair synthesis and ligation in gg ner", "Gap junction assembly", "Gap junction degradation", "Gap junction trafficking and regulation", "Gastrin creb signalling pathway via pkc and mapk", "Gdp fucose biosynthesis", "Gene and protein expression by jak stat signaling after interleukin 12 stimulation", "Gene silencing by rna", "Generation of second messenger molecules", "Global genome nucleotide excision repair gg ner", "Glucagon like peptide 1 glp1 regulates insulin secretion", "Glucagon signaling in metabolic regulation", "Glucagon type ligand receptors", "Gluconeogenesis", "Glucose metabolism", "Glucuronidation", "Glutamate and glutamine metabolism", "Glutamate neurotransmitter release cycle", "Glutathione conjugation", "Glutathione synthesis and recycling", "Glycerophospholipid biosynthesis", "Glycerophospholipid catabolism", "Glycogen breakdown glycogenolysis", "Glycogen metabolism", "Glycogen storage diseases", "Glycogen synthesis", "Glycolysis", "Glycosaminoglycan metabolism", "Glycosphingolipid metabolism", "Glyoxylate metabolism and glycine degradation", "Golgi associated vesicle biogenesis", "Golgi cisternae pericentriolar stack reorganization", "Golgi to er retrograde transport", "Gp1b ix v activation signalling", "Gpcr ligand binding", "Gpvi mediated activation cascade", "Grb2 events in erbb2 signaling", "Grb2 sos provides linkage to mapk signaling for integrins", "Growth hormone receptor signaling", "Hats acetylate histones", "Hcmv early events", "Hcmv infection", "Hcmv late events", "Hdacs deacetylate histones", "Hdl assembly", "Hdl clearance", "Hdms demethylate histones", "Hdr through homologous recombination hrr", "Hdr through mmej alt nhej", "Hdr through single strand annealing ssa", "Hedgehog ligand biogenesis", "Hedgehog off state", "Hedgehog on state", "Heme biosynthesis", "Heme degradation", "Heme signaling", "Hemostasis", "Heparan sulfate heparin hs gag metabolism", "Hiv elongation arrest and recovery", "Hiv infection", "Hiv life cycle", "Hiv transcription elongation", "Hiv transcription initiation", "Homologous dna pairing and strand exchange", "Homology directed repair", "Host interactions of hiv factors", "Hs gag biosynthesis", "Hs gag degradation", "Hsf1 activation", "Hsf1 dependent transactivation", "Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand", "Hur elavl1 binds and stabilizes mrna", "Hyaluronan metabolism", "Hyaluronan uptake and degradation", "Hydrolysis of lpc", "Ikba variant leads to eda id", "Ikk complex recruitment mediated by rip1", "Immunoregulatory interactions between a lymphoid and a non lymphoid cell", "Inactivation of cdc42 and rac1", "Inactivation of csf3 g csf signaling", "Incretin synthesis secretion and inactivation", "Infection with mycobacterium tuberculosis", "Infectious disease", "Inflammasomes", "Influenza infection", "Inhibition of dna recombination at telomere", "Inhibition of replication initiation of damaged dna by rb1 e2f1", "Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components", "Initiation of nuclear envelope ne reformation", "Inla mediated entry of listeria monocytogenes into host cells", "Inlb mediated entry of listeria monocytogenes into host cell", "Innate immune system", "Inositol phosphate metabolism", "Insertion of tail anchored proteins into the endoplasmic reticulum membrane", "Insulin processing", "Insulin receptor recycling", "Insulin receptor signalling cascade", "Integration of energy metabolism", "Integration of provirus", "Integrin cell surface interactions", "Integrin signaling", "Interaction between l1 and ankyrins", "Interactions of rev with host cellular proteins", "Interactions of vpr with host cellular proteins", "Interconversion of nucleotide di and triphosphates", "Interferon alpha beta signaling", "Interferon gamma signaling", "Interferon signaling", "Interleukin 1 family signaling", "Interleukin 1 signaling", "Interleukin 12 family signaling", "Interleukin 12 signaling", "Interleukin 15 signaling", "Interleukin 17 signaling", "Interleukin 2 family signaling", "Interleukin 2 signaling", "Interleukin 20 family signaling", "Interleukin 21 signaling", "Interleukin 23 signaling", "Interleukin 27 signaling", "Interleukin 3 interleukin 5 and gm csf signaling", "Interleukin 35 signalling", "Interleukin 37 signaling", "Interleukin 4 and interleukin 13 signaling", "Interleukin 6 family signaling", "Interleukin 6 signaling", "Interleukin 7 signaling", "Interleukin 9 signaling", "Interleukin receptor shc signaling", "Intra golgi and retrograde golgi to er traffic", "Intra golgi traffic", "Intracellular signaling by second messengers", "Intraflagellar transport", "Intrinsic pathway for apoptosis", "Intrinsic pathway of fibrin clot formation", "Inwardly rectifying k channels", "Ion channel transport", "Ion homeostasis", "Ion transport by p type atpases", "Ionotropic activity of kainate receptors", "Irak1 recruits ikk complex", "Irak2 mediated activation of tak1 complex", "Irak4 deficiency tlr2 4", "Ire1alpha activates chaperones", "Irf3 mediated activation of type 1 ifn", "Irf3 mediated induction of type i ifn", "Iron uptake and transport", "Irs mediated signalling", "Jnk c jun kinases phosphorylation and activation mediated by activated human tak1", "Josephin domain dubs", "Keratan sulfate biosynthesis", "Keratan sulfate degradation", "Keratan sulfate keratin metabolism", "Keratinization", "Ketone body metabolism", "Killing mechanisms", "Kinesins", "Ksrp khsrp binds and destabilizes mrna", "L1cam interactions", "Lagging strand synthesis", "Laminin interactions", "Late endosomal microautophagy", "Ldl clearance", "Ldl remodeling", "Leishmania infection", "Lgi adam interactions", "Linoleic acid la metabolism", "Lipophagy", "Listeria monocytogenes entry into host cells", "Long term potentiation", "Loss of function of mecp2 in rett syndrome", "Loss of mecp2 binding ability to the ncor smrt complex", "Lrr flii interacting protein 1 lrrfip1 activates type i ifn production", "Lysine catabolism", "Lysosome vesicle biogenesis", "M phase", "Map2k and mapk activation", "Map3k8 tpl2 dependent mapk1 3 activation", "Mapk family signaling cascades", "Mapk targets nuclear events mediated by map kinases", "Mapk1 erk2 activation", "Mapk3 erk1 activation", "Mapk6 mapk4 signaling", "Mastl facilitates mitotic progression", "Maturation of protein 3a", "Maturation of sars cov 1 nucleoprotein", "Maturation of sars cov 1 spike protein", "Maturation of sars cov 2 nucleoprotein", "Maturation of sars cov 2 spike protein", "Mecp2 regulates neuronal receptors and channels", "Mecp2 regulates transcription factors", "Mecp2 regulates transcription of neuronal ligands", "Meiosis", "Meiotic recombination", "Meiotic synapsis", "Membrane trafficking", "Met activates pi3k akt signaling", "Met activates ptk2 signaling", "Met activates ptpn11", "Met activates rap1 and rac1", "Met activates ras signaling", "Met interacts with tns proteins", "Met promotes cell motility", "Met receptor activation", "Met receptor recycling", "Metabolic disorders of biological oxidation enzymes", "Metabolism of amino acids and derivatives", "Metabolism of carbohydrates", "Metabolism of cofactors", "Metabolism of fat soluble vitamins", "Metabolism of folate and pterines", "Metabolism of ingested semet sec mesec into h2se", "Metabolism of lipids", "Metabolism of nitric oxide nos3 activation and regulation", "Metabolism of nucleotides", "Metabolism of polyamines", "Metabolism of porphyrins", "Metabolism of rna", "Metabolism of steroid hormones", "Metabolism of steroids", "Metabolism of vitamins and cofactors", "Metabolism of water soluble vitamins and cofactors", "Metal ion slc transporters", "Metalloprotease dubs", "Methionine salvage pathway", "Methylation", "Mhc class ii antigen presentation", "Microrna mirna biogenesis", "Miro gtpase cycle", "Miscellaneous transport and binding events", "Mismatch repair", "Mitochondrial biogenesis", "Mitochondrial calcium ion transport", "Mitochondrial fatty acid beta oxidation", "Mitochondrial fatty acid beta oxidation of saturated fatty acids", "Mitochondrial fatty acid beta oxidation of unsaturated fatty acids", "Mitochondrial iron sulfur cluster biogenesis", "Mitochondrial protein import", "Mitochondrial translation", "Mitochondrial trna aminoacylation", "Mitophagy", "Mitotic g1 phase and g1 s transition", "Mitotic g2 g2 m phases", "Mitotic metaphase and anaphase", "Mitotic prometaphase", "Mitotic prophase", "Mitotic spindle checkpoint", "Mitotic telophase cytokinesis", "Molecules associated with elastic fibres", "Molybdenum cofactor biosynthesis", "Mrna capping", "Mrna decay by 3 to 5 exoribonuclease", "Mrna decay by 5 to 3 exoribonuclease", "Mrna editing", "Mrna editing c to u conversion", "Mrna splicing", "Mrna splicing minor pathway", "Mtor signalling", "Mtorc1 mediated signalling", "Mucopolysaccharidoses", "Muscle contraction", "Myd88 independent tlr4 cascade", "Myoclonic epilepsy of lafora", "Myogenesis", "N glycan antennae elongation in the medial trans golgi", "N glycan trimming and elongation in the cis golgi", "N glycan trimming in the er and calnexin calreticulin cycle", "Na cl dependent neurotransmitter transporters", "Nade modulates death signalling", "Ncam signaling for neurite out growth", "Ncam1 interactions", "Nectin necl trans heterodimerization", "Neddylation", "Nef and signal transduction", "Nef mediated cd4 down regulation", "Nef mediated cd8 down regulation", "Nef mediated downregulation of mhc class i complex cell surface expression", "Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters", "Negative epigenetic regulation of rrna expression", "Negative feedback regulation of mapk pathway", "Negative regulation of fgfr1 signaling", "Negative regulation of fgfr2 signaling", "Negative regulation of fgfr3 signaling", "Negative regulation of fgfr4 signaling", "Negative regulation of flt3", "Negative regulation of mapk pathway", "Negative regulation of met activity", "Negative regulation of nmda receptor mediated neuronal transmission", "Negative regulation of notch4 signaling", "Negative regulation of tcf dependent signaling by dvl interacting proteins", "Negative regulation of the pi3k akt network", "Negative regulators of ddx58 ifih1 signaling", "Nephrin family interactions", "Nervous system development", "Netrin 1 signaling", "Netrin mediated repulsion signals", "Neurexins and neuroligins", "Neurofascin interactions", "Neuronal system", "Neurotoxicity of clostridium toxins", "Neurotransmitter clearance", "Neurotransmitter receptors and postsynaptic signal transmission", "Neurotransmitter release cycle", "Neutrophil degranulation", "Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10", "Nf kb is activated and signals survival", "Ngf stimulated transcription", "Nicotinamide salvaging", "Nicotinate metabolism", "Nod1 2 signaling pathway", "Non integrin membrane ecm interactions", "Noncanonical activation of notch3", "Nonhomologous end joining nhej", "Nonsense mediated decay nmd", "Nostrin mediated enos trafficking", "Notch hlh transcription pathway", "Notch1 intracellular domain regulates transcription", "Notch2 activation and transmission of signal to the nucleus", "Notch2 intracellular domain regulates transcription", "Notch3 activation and transmission of signal to the nucleus", "Notch3 intracellular domain regulates transcription", "Notch4 activation and transmission of signal to the nucleus", "Notch4 intracellular domain regulates transcription", "Nr1h2 and nr1h3 mediated signaling", "Nr1h2 nr1h3 regulate gene expression linked to gluconeogenesis", "Nr1h2 nr1h3 regulate gene expression linked to lipogenesis", "Nr1h2 nr1h3 regulate gene expression linked to triglyceride lipolysis in adipose", "Nr1h2 nr1h3 regulate gene expression to control bile acid homeostasis", "Nr1h2 nr1h3 regulate gene expression to limit cholesterol uptake", "Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux", "Nrage signals death through jnk", "Nrcam interactions", "Nrif signals cell death from the nucleus", "Ns1 mediated effects on host pathways", "Ntrk2 activates rac1", "Nuclear envelope breakdown", "Nuclear envelope ne reassembly", "Nuclear events kinase and transcription factor activation", "Nuclear events stimulated by alk signaling in cancer", "Nuclear import of rev protein", "Nuclear pore complex npc disassembly", "Nuclear receptor transcription pathway", "Nuclear signaling by erbb4", "Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways", "Nucleotide biosynthesis", "Nucleotide catabolism", "Nucleotide excision repair", "Nucleotide salvage", "O glycosylation of tsr domain containing proteins", "O linked glycosylation", "O linked glycosylation of mucins", "Oas antiviral response", "Oncogene induced senescence", "Oncogenic mapk signaling", "Opioid signalling", "Orc1 removal from chromatin", "Organelle biogenesis and maintenance", "Organic anion transporters", "Other interleukin signaling", "Other semaphorin interactions", "Ovarian tumor domain proteases", "Oxidative stress induced senescence", "P130cas linkage to mapk signaling for integrins", "P38mapk events", "P75 ntr receptor mediated signalling", "P75ntr negatively regulates cell cycle via sc1", "P75ntr recruits signalling complexes", "P75ntr regulates axonogenesis", "P75ntr signals via nf kb", "Parasite infection", "Passive transport by aquaporins", "Pcna dependent long patch base excision repair", "Pcp ce pathway", "Pd 1 signaling", "Pecam1 interactions", "Pentose phosphate pathway", "Peptide hormone metabolism", "Peptide ligand binding receptors", "Perk regulates gene expression", "Peroxisomal lipid metabolism", "Peroxisomal protein import", "Pexophagy", "Phase 0 rapid depolarisation", "Phase 2 plateau phase", "Phase 3 rapid repolarisation", "Phase i functionalization of compounds", "Phase ii conjugation of compounds", "Phenylalanine and tyrosine metabolism", "Phenylalanine metabolism", "Phosphate bond hydrolysis by nudt proteins", "Phospholipase c mediated cascade fgfr2", "Phospholipase c mediated cascade fgfr4", "Phospholipid metabolism", "Phosphorylation of emi1", "Phosphorylation of the apc c", "Pi 3k cascade fgfr1", "Pi 3k cascade fgfr2", "Pi 3k cascade fgfr3", "Pi 3k cascade fgfr4", "Pi metabolism", "Pi3k akt activation", "Pi3k akt signaling in cancer", "Pi3k events in erbb2 signaling", "Pi5p regulates tp53 acetylation", "Pink1 prkn mediated mitophagy", "Piwi interacting rna pirna biogenesis", "Pka activation in glucagon signalling", "Pka mediated phosphorylation of creb", "Pka mediated phosphorylation of key metabolic factors", "Pkmts methylate histone lysines", "Plasma lipoprotein assembly", "Plasma lipoprotein assembly remodeling and clearance", "Plasma lipoprotein clearance", "Plasma lipoprotein remodeling", "Platelet activation signaling and aggregation", "Platelet adhesion to exposed collagen", "Platelet aggregation plug formation", "Platelet calcium homeostasis", "Platelet homeostasis", "Platelet sensitization by ldl", "Polb dependent long patch base excision repair", "Polo like kinase mediated events", "Polymerase switching", "Polymerase switching on the c strand of the telomere", "Positive epigenetic regulation of rrna expression", "Post chaperonin tubulin folding pathway", "Post translational modification synthesis of gpi anchored proteins", "Post translational protein modification", "Postmitotic nuclear pore complex npc reformation", "Potassium channels", "Potential therapeutics for sars", "Pp2a mediated dephosphorylation of key metabolic factors", "Prc2 methylates histones and dna", "Pre notch expression and processing", "Pre notch processing in golgi", "Pre notch processing in the endoplasmic reticulum", "Pregnenolone biosynthesis", "Presynaptic function of kainate receptors", "Prevention of phagosomal lysosomal fusion", "Processing and activation of sumo", "Processing of capped intron containing pre mrna", "Processing of capped intronless pre mrna", "Processing of dna double strand break ends", "Processing of intronless pre mrnas", "Processing of smdt1", "Processive synthesis on the c strand of the telomere", "Processive synthesis on the lagging strand", "Programmed cell death", "Prolactin receptor signaling", "Prolonged erk activation events", "Propionyl coa catabolism", "Prostacyclin signalling through prostacyclin receptor", "Protein folding", "Protein localization", "Protein methylation", "Protein protein interactions at synapses", "Protein repair", "Protein ubiquitination", "Proton coupled monocarboxylate transport", "Pten regulation", "Ptk6 expression", "Ptk6 promotes hif1a stabilization", "Ptk6 regulates cell cycle", "Ptk6 regulates proteins involved in rna processing", "Ptk6 regulates rho gtpases ras gtpase and map kinases", "Ptk6 regulates rtks and their effectors akt1 and dok1", "Purine catabolism", "Purine ribonucleoside monophosphate biosynthesis", "Purine salvage", "Purinergic signaling in leishmaniasis infection", "Pyrimidine catabolism", "Pyrimidine salvage", "Pyroptosis", "Pyruvate metabolism", "Pyruvate metabolism and citric acid tca cycle", "Ra biosynthesis pathway", "Rab gefs exchange gtp for gdp on rabs", "Rab geranylgeranylation", "Rab regulation of trafficking", "Rac1 gtpase cycle", "Rac2 gtpase cycle", "Rac3 gtpase cycle", "Raf activation", "Raf independent mapk1 3 activation", "Rap1 signalling", "Ras activation upon ca2 influx through nmda receptor", "Ras processing", "Reactions specific to the complex n glycan synthesis pathway", "Receptor mediated mitophagy", "Receptor type tyrosine protein phosphatases", "Recognition and association of dna glycosylase with site containing an affected purine", "Recognition of dna damage by pcna containing replication complex", "Recruitment of mitotic centrosome proteins and complexes", "Recruitment of numa to mitotic centrosomes", "Recycling of eif2 gdp", "Recycling pathway of l1", "Reduction of cytosolic ca levels", "Regulated necrosis", "Regulated proteolysis of p75ntr", "Regulation by c flip", "Regulation of bach1 activity", "Regulation of beta cell development", "Regulation of cholesterol biosynthesis by srebp srebf", "Regulation of commissural axon pathfinding by slit and robo", "Regulation of cytoskeletal remodeling and cell spreading by ipp complex components", "Regulation of expression of slits and robos", "Regulation of foxo transcriptional activity by acetylation", "Regulation of gene expression in beta cells", "Regulation of gene expression in late stage branching morphogenesis pancreatic bud precursor cells", "Regulation of glucokinase by glucokinase regulatory protein", "Regulation of glycolysis by fructose 2 6 bisphosphate metabolism", "Regulation of hmox1 expression and activity", "Regulation of hsf1 mediated heat shock response", "Regulation of ifna signaling", "Regulation of ifng signaling", "Regulation of innate immune responses to cytosolic dna", "Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps", "Regulation of insulin secretion", "Regulation of kit signaling", "Regulation of lipid metabolism by pparalpha", "Regulation of localization of foxo transcription factors", "Regulation of mecp2 expression and activity", "Regulation of mrna stability by proteins that bind au rich elements", "Regulation of plk1 activity at g2 m transition", "Regulation of pten gene transcription", "Regulation of pten localization", "Regulation of pten mrna translation", "Regulation of pten stability and activity", "Regulation of pyruvate dehydrogenase pdh complex", "Regulation of ras by gaps", "Regulation of runx1 expression and activity", "Regulation of runx2 expression and activity", "Regulation of runx3 expression and activity", "Regulation of signaling by cbl", "Regulation of tlr by endogenous ligand", "Regulation of tnfr1 signaling", "Regulation of tp53 activity", "Regulation of tp53 activity through acetylation", "Regulation of tp53 activity through association with co factors", "Regulation of tp53 activity through methylation", "Regulation of tp53 activity through phosphorylation", "Regulation of tp53 expression and degradation", "Release of apoptotic factors from the mitochondria", "Release of hh np from the secreting cell", "Repression of wnt target genes", "Reproduction", "Resolution of abasic sites ap sites", "Resolution of ap sites via the multiple nucleotide patch replacement pathway", "Resolution of d loop structures", "Resolution of d loop structures through synthesis dependent strand annealing sdsa", "Resolution of sister chromatid cohesion", "Respiratory electron transport", "Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins", "Response of eif2ak1 hri to heme deficiency", "Response of eif2ak4 gcn2 to amino acid deficiency", "Response of mtb to phagocytosis", "Response to elevated platelet cytosolic ca2", "Ret signaling", "Retrograde neurotrophin signalling", "Retrograde transport at the trans golgi network", "Rho gtpase cycle", "Rho gtpase effectors", "Rho gtpases activate cit", "Rho gtpases activate formins", "Rho gtpases activate iqgaps", "Rho gtpases activate ktn1", "Rho gtpases activate nadph oxidases", "Rho gtpases activate paks", "Rho gtpases activate pkns", "Rho gtpases activate rhotekin and rhophilins", "Rho gtpases activate rocks", "Rho gtpases activate wasps and waves", "Rhoa gtpase cycle", "Rhob gtpase cycle", "Rhobtb gtpase cycle", "Rhobtb1 gtpase cycle", "Rhobtb2 gtpase cycle", "Rhobtb3 atpase cycle", "Rhoc gtpase cycle", "Rhod gtpase cycle", "Rhof gtpase cycle", "Rhog gtpase cycle", "Rhoh gtpase cycle", "Rhoj gtpase cycle", "Rhoq gtpase cycle", "Rhot1 gtpase cycle", "Rhou gtpase cycle", "Rhov gtpase cycle", "Rip mediated nfkb activation via zbp1", "Ripk1 mediated regulated necrosis", "Rmts methylate histone arginines", "Rna polymerase i promoter escape", "Rna polymerase i transcription", "Rna polymerase i transcription initiation", "Rna polymerase i transcription termination", "Rna polymerase ii transcribes snrna genes", "Rna polymerase ii transcription", "Rna polymerase ii transcription termination", "Rna polymerase iii chain elongation", "Rna polymerase iii transcription", "Rna polymerase iii transcription initiation from type 1 promoter", "Rna polymerase iii transcription initiation from type 3 promoter", "Rna polymerase iii transcription termination", "Rnd1 gtpase cycle", "Rnd2 gtpase cycle", "Rnd3 gtpase cycle", "Robo receptors bind akap5", "Role of abl in robo slit signaling", "Role of lat2 ntal lab on calcium mobilization", "Role of phospholipids in phagocytosis", "Role of second messengers in netrin 1 signaling", "Rora activates gene expression", "Ros and rns production in phagocytes", "Rrna modification in the mitochondrion", "Rrna modification in the nucleus and cytosol", "Rrna processing", "Rrna processing in the mitochondrion", "Rsk activation", "Runx1 interacts with co factors whose precise effect on runx1 targets is not known", "Runx1 regulates estrogen receptor mediated transcription", "Runx1 regulates expression of components of tight junctions", "Runx1 regulates genes involved in megakaryocyte differentiation and platelet function", "Runx1 regulates transcription of genes involved in differentiation of hscs", "Runx1 regulates transcription of genes involved in differentiation of myeloid cells", "Runx2 regulates bone development", "Runx2 regulates genes involved in cell migration", "Runx2 regulates osteoblast differentiation", "Runx3 regulates cdkn1a transcription", "Runx3 regulates notch signaling", "Runx3 regulates p14 arf", "Runx3 regulates wnt signaling", "S phase", "Sars cov 1 infection", "Sars cov 2 infection", "Sars cov infections", "Scavenging by class a receptors", "Scavenging by class b receptors", "Scavenging by class f receptors", "Scavenging of heme from plasma", "Scf skp2 mediated degradation of p27 p21", "Sealing of the nuclear envelope ne by escrt iii", "Selective autophagy", "Selenoamino acid metabolism", "Sema3a pak dependent axon repulsion", "Sema3a plexin repulsion signaling by inhibiting integrin adhesion", "Sema4d in semaphorin signaling", "Sema4d induced cell migration and growth cone collapse", "Sema4d mediated inhibition of cell attachment and migration", "Semaphorin interactions", "Senescence associated secretory phenotype sasp", "Sensing of dna double strand breaks", "Sensory perception", "Sensory processing of sound", "Sensory processing of sound by outer hair cells of the cochlea", "Separation of sister chromatids", "Serine biosynthesis", "Shc mediated cascade fgfr1", "Shc mediated cascade fgfr3", "Shc mediated cascade fgfr4", "Shc related events triggered by igf1r", "Shc1 events in egfr signaling", "Shc1 events in erbb2 signaling", "Shc1 events in erbb4 signaling", "Sialic acid metabolism", "Signal amplification", "Signal attenuation", "Signal regulatory protein family interactions", "Signal transduction by l1", "Signaling by activin", "Signaling by alk", "Signaling by alk in cancer", "Signaling by bmp", "Signaling by braf and raf1 fusions", "Signaling by csf3 g csf", "Signaling by ctnnb1 phospho site mutants", "Signaling by cytosolic fgfr1 fusion mutants", "Signaling by egfr", "Signaling by egfr in cancer", "Signaling by erbb2", "Signaling by erbb2 ecd mutants", "Signaling by erbb2 in cancer", "Signaling by erbb4", "Signaling by erythropoietin", "Signaling by fgfr", "Signaling by fgfr in disease", "Signaling by fgfr1", "Signaling by fgfr1 in disease", "Signaling by fgfr2", "Signaling by fgfr2 iiia tm", "Signaling by fgfr2 in disease", "Signaling by fgfr3", "Signaling by fgfr3 fusions in cancer", "Signaling by fgfr4", "Signaling by fgfr4 in disease", "Signaling by flt3 fusion proteins", "Signaling by flt3 itd and tkd mutants", "Signaling by gpcr", "Signaling by hedgehog", "Signaling by hippo", "Signaling by insulin receptor", "Signaling by interleukins", "Signaling by kit in disease", "Signaling by leptin", "Signaling by mapk mutants", "Signaling by membrane tethered fusions of pdgfra or pdgfrb", "Signaling by met", "Signaling by moderate kinase activity braf mutants", "Signaling by mras complex mutants", "Signaling by mst1", "Signaling by nodal", "Signaling by notch", "Signaling by notch1", "Signaling by notch1 hd domain mutants in cancer", "Signaling by notch1 pest domain mutants in cancer", "Signaling by notch1 t 7 9 notch1 m1580 k2555 translocation mutant", "Signaling by notch2", "Signaling by notch3", "Signaling by notch4", "Signaling by ntrk2 trkb", "Signaling by ntrk3 trkc", "Signaling by ntrks", "Signaling by nuclear receptors", "Signaling by pdgf", "Signaling by pdgfr in disease", "Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants", "Signaling by ptk6", "Signaling by receptor tyrosine kinases", "Signaling by retinoic acid", "Signaling by rho gtpases miro gtpases and rhobtb3", "Signaling by robo receptors", "Signaling by scf kit", "Signaling by tgf beta receptor complex", "Signaling by tgf beta receptor complex in cancer", "Signaling by tgfb family members", "Signaling by the b cell receptor bcr", "Signaling by type 1 insulin like growth factor 1 receptor igf1r", "Signaling by vegf", "Signaling by wnt", "Signaling by wnt in cancer", "Signalling to erks", "Signalling to ras", "Sirt1 negatively regulates rrna expression", "Slbp dependent processing of replication dependent histone pre mrnas", "Slc mediated transmembrane transport", "Slc transporter disorders", "Smac xiap regulated apoptotic response", "Smad2 smad3 smad4 heterotrimer regulates transcription", "Small interfering rna sirna biogenesis", "Smooth muscle contraction", "Snrnp assembly", "Sodium calcium exchangers", "Sos mediated signalling", "Sphingolipid de novo biosynthesis", "Sphingolipid metabolism", "Spry regulation of fgf signaling", "Srp dependent cotranslational protein targeting to membrane", "Stabilization of p53", "Stat3 nuclear events downstream of alk signaling", "Stat5 activation", "Stat5 activation downstream of flt3 itd mutants", "Stimuli sensing channels", "Sting mediated induction of host immune responses", "Striated muscle contraction", "Sulfide oxidation to sulfate", "Sulfur amino acid metabolism", "Sumo is conjugated to e1 uba2 sae1", "Sumo is proteolytically processed", "Sumo is transferred from e1 to e2 ube2i ubc9", "Sumoylation", "Sumoylation of chromatin organization proteins", "Sumoylation of dna damage response and repair proteins", "Sumoylation of dna methylation proteins", "Sumoylation of dna replication proteins", "Sumoylation of intracellular receptors", "Sumoylation of rna binding proteins", "Sumoylation of sumoylation proteins", "Sumoylation of transcription cofactors", "Sumoylation of transcription factors", "Sumoylation of ubiquitinylation proteins", "Suppression of apoptosis", "Suppression of phagosomal maturation", "Surfactant metabolism", "Switching of origins to a post replicative state", "Synaptic adhesion like molecules", "Syndecan interactions", "Synthesis of 5 eicosatetraenoic acids", "Synthesis of active ubiquitin roles of e1 and e2 enzymes", "Synthesis of bile acids and bile salts", "Synthesis of bile acids and bile salts via 24 hydroxycholesterol", "Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol", "Synthesis of diphthamide eef2", "Synthesis of dna", "Synthesis of dolichyl phosphate", "Synthesis of gdp mannose", "Synthesis of glycosylphosphatidylinositol gpi", "Synthesis of ip2 ip and ins in the cytosol", "Synthesis of ip3 and ip4 in the cytosol", "Synthesis of ketone bodies", "Synthesis of leukotrienes lt and eoxins ex", "Synthesis of lipoxins lx", "Synthesis of pa", "Synthesis of pc", "Synthesis of pe", "Synthesis of pg", "Synthesis of pi", "Synthesis of pips at the early endosome membrane", "Synthesis of pips at the er membrane", "Synthesis of pips at the golgi membrane", "Synthesis of pips at the late endosome membrane", "Synthesis of pips at the plasma membrane", "Synthesis of prostaglandins pg and thromboxanes tx", "Synthesis of substrates in n glycan biosythesis", "Synthesis of udp n acetyl glucosamine", "Synthesis of very long chain fatty acyl coas", "Synthesis secretion and deacylation of ghrelin", "Synthesis secretion and inactivation of glucagon like peptide 1 glp 1", "Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip", "Tak1 activates nfkb by phosphorylation and activation of ikks complex", "Tbc rabgaps", "Tcf dependent signaling in response to wnt", "Tcr signaling", "Telomere c strand lagging strand synthesis", "Telomere c strand synthesis initiation", "Telomere extension by telomerase", "Telomere maintenance", "Terminal pathway of complement", "Termination of translesion dna synthesis", "Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation", "Tfap2 ap 2 family regulates transcription of growth factors and their receptors", "Tfap2a acts as a transcriptional repressor during retinoic acid induced cell differentiation", "Tgf beta receptor signaling activates smads", "Tgf beta receptor signaling in emt epithelial to mesenchymal transition", "The activation of arylsulfatases", "The canonical retinoid cycle in rods twilight vision", "The citric acid tca cycle and respiratory electron transport", "The nlrp3 inflammasome", "The phototransduction cascade", "The role of gtse1 in g2 m progression after g2 checkpoint", "The role of nef in hiv 1 replication and disease pathogenesis", "Thrombin signalling through proteinase activated receptors pars", "Thromboxane signalling through tp receptor", "Ticam1 rip1 mediated ikk complex recruitment", "Ticam1 traf6 dependent induction of tak1 complex", "Tie2 signaling", "Tight junction interactions", "Tnf signaling", "Tnfr1 induced nfkappab signaling pathway", "Tnfr1 induced proapoptotic signaling", "Tnfr1 mediated ceramide production", "Tnfr2 non canonical nf kb pathway", "Toll like receptor 9 tlr9 cascade", "Toll like receptor cascades", "Toll like receptor tlr1 tlr2 cascade", "Toxicity of botulinum toxin type d botd", "Tp53 regulates metabolic genes", "Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain", "Tp53 regulates transcription of caspase activators and caspases", "Tp53 regulates transcription of cell cycle genes", "Tp53 regulates transcription of cell death genes", "Tp53 regulates transcription of death receptors and ligands", "Tp53 regulates transcription of dna repair genes", "Tp53 regulates transcription of genes involved in cytochrome c release", "Tp53 regulates transcription of genes involved in g1 cell cycle arrest", "Tp53 regulates transcription of genes involved in g2 cell cycle arrest", "Tp53 regulates transcription of several additional cell death genes whose specific roles in p53 dependent apoptosis remain uncertain", "Traf3 dependent irf activation pathway", "Traf6 mediated induction of tak1 complex within tlr4 complex", "Traf6 mediated irf7 activation", "Traf6 mediated irf7 activation in tlr7 8 or 9 signaling", "Traf6 mediated nf kb activation", "Trafficking and processing of endosomal tlr", "Trafficking of ampa receptors", "Trafficking of glur2 containing ampa receptors", "Trafficking of myristoylated proteins to the cilium", "Trans golgi network vesicle budding", "Transcription coupled nucleotide excision repair tc ner", "Transcription of e2f targets under negative control by dream complex", "Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1", "Transcription of the hiv genome", "Transcriptional activation of mitochondrial biogenesis", "Transcriptional activity of smad2 smad3 smad4 heterotrimer", "Transcriptional regulation by e2f6", "Transcriptional regulation by mecp2", "Transcriptional regulation by runx1", "Transcriptional regulation by runx2", "Transcriptional regulation by runx3", "Transcriptional regulation by small rnas", "Transcriptional regulation by the ap 2 tfap2 family of transcription factors", "Transcriptional regulation by tp53", "Transcriptional regulation by ventx", "Transcriptional regulation of granulopoiesis", "Transcriptional regulation of white adipocyte differentiation", "Transferrin endocytosis and recycling", "Translation", "Translation of replicase and assembly of the replication transcription complex", "Translation of sars cov 1 structural proteins", "Translation of sars cov 2 structural proteins", "Translesion synthesis by polh", "Translesion synthesis by polk", "Translesion synthesis by y family dna polymerases bypasses lesions on dna template", "Translocation of slc2a4 glut4 to the plasma membrane", "Transmission across chemical synapses", "Transport and synthesis of paps", "Transport of bile salts and organic acids metal ions and amine compounds", "Transport of connexons to the plasma membrane", "Transport of fatty acids", "Transport of inorganic cations anions and amino acids oligopeptides", "Transport of mature mrnas derived from intronless transcripts", "Transport of mature transcript to cytoplasm", "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane", "Transport of nucleotide sugars", "Transport of small molecules", "Transport of the slbp dependant mature mrna", "Transport of vitamins nucleosides and related molecules", "Transport to the golgi and subsequent modification", "Triglyceride biosynthesis", "Triglyceride catabolism", "Triglyceride metabolism", "Tristetraprolin ttp zfp36 binds and destabilizes mrna", "Trna aminoacylation", "Trna modification in the mitochondrion", "Trna modification in the nucleus and cytosol", "Trna processing", "Trna processing in the mitochondrion", "Trna processing in the nucleus", "Tryptophan catabolism", "Type i hemidesmosome assembly", "Tyrosine catabolism", "Tysnd1 cleaves peroxisomal proteins", "Ub specific processing proteases", "Ubiquinol biosynthesis", "Uch proteinases", "Unblocking of nmda receptors glutamate binding and activation", "Unfolded protein response upr", "Unwinding of dna", "Uptake and actions of bacterial toxins", "Uptake and function of anthrax toxins", "Uptake and function of diphtheria toxin", "Urea cycle", "Vasopressin regulates renal water homeostasis via aquaporins", "Vegfr2 mediated cell proliferation", "Vegfr2 mediated vascular permeability", "Vesicle mediated transport", "Viral messenger rna synthesis", "Visual phototransduction", "Vitamin b2 riboflavin metabolism", "Vitamin b5 pantothenate metabolism", "Vitamin c ascorbate metabolism", "Vitamin d calciferol metabolism", "Vldl assembly", "Vldlr internalisation and degradation", "Vxpx cargo targeting to cilium", "Wax and plasmalogen biosynthesis", "Wnt ligand biogenesis and trafficking", "Wnt mediated activation of dvl", "Wnt5a dependent internalization of fzd2 fzd5 and ror2", "Wnt5a dependent internalization of fzd4", "Zbp1 dai mediated induction of type i ifns", "Zinc efflux and compartmentalization by the slc30 family", "Zinc transporters"], "available_proteins": ["AAAS", "AACS", "AARS", "AARS2", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAM17", "ADAM9", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADK", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT1S1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG2", "ALG5", "ALKBH5", "ALYREF", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANLN", "ANO6", "ANXA1", "ANXA2", "ANXA6", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "AP3S1", "APBB1", "APC", "APEH", "APEX1", "APLP2", "APOBEC3C", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP2", "ARG2", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID2", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL6IP5", "ARMC8", "ARMCX3", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASCC2", "ASCC3", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD3B", "ATG4B", "ATG9A", "ATIC", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATRX", "AURKB", "B4GAT1", "BABAM1", "BABAM2", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAX", "BAZ1B", "BAZ2A", "BCAP31", "BCAS2", "BCAT2", "BCS1L", "BDH2", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BRCA1", "BRD2", "BRD4", "BRD7", "BRD8", "BSG", "BTRC", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "C19orf70", "C1D", "C1QBP", "C1orf35", "C2CD5", "CAB39", "CAD", "CADM1", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2G", "CAMLG", "CAND1", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN7", "CAPNS1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CAST", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC22", "CCDC8", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC20", "CDC23", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC6", "CDC73", "CDCA5", "CDCA8", "CDH2", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CDKAL1", "CDS2", "CEP135", "CEP250", "CERS1", "CERS2", "CETN2", "CFL1", "CGN", "CHAC2", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHP1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLCN7", "CLINT1", "CLNS1A", "CLTA", "CLTC", "CLU", "CMAS", "CMPK1", "CNDP2", "CNN2", "CNOT1", "CNOT10", "CNOT11", "CNOT2", "CNOT7", "CNOT9", "COG3", "COG7", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ9", "COTL1", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CREB1", "CREG1", "CRKL", "CRNKL1", "CRTAP", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CWC15", "CWC22", "CYB5B", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCD", "DCP1A", "DCP2", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX52", "DDX56", "DDX6", "DECR1", "DEK", "DENND4C", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS4", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX36", "DHX37", "DHX38", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLST", "DMAP1", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK7", "DOHH", "DOLPP1", "DPH2", "DPH5", "DPM1", "DPYSL2", "DPYSL3", "DPYSL5", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DTYMK", "DUSP3", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFTUD2", "EGFR", "EHD1", "EHHADH", "EHMT2", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC3", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENPP1", "ENSA", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPN1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERCC2", "ERCC3", "ERCC6L", "ERLIN1", "ERLIN2", "ERO1A", "ERP44", "ESD", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EYA4", "EZH2", "EZR", "F11R", "FABP5", "FADS2", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120B", "FAM3C", "FAM49B", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FAU", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FIP1L1", "FKBP14", "FKBP1A", "FKBP4", "FKBP5", "FKBP8", "FKBP9", "FLAD1", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FN3KRP", "FNBP1L", "FOXK1", "FOXK2", "FSCN1", "FSTL1", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FUS", "FXR1", "FYTTD1", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GGH", "GGPS1", "GHDC", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLRX3", "GLRX5", "GLS", "GLUD1", "GM2A", "GMPPA", "GMPPB", "GMPS", "GNA13", "GNAI2", "GNAI3", "GNE", "GNG12", "GNG5", "GNL3", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA4", "GOLGA5", "GOLGB1", "GOLIM4", "GOPC", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPD2", "GPHN", "GPI", "GPKOW", "GPS1", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP3", "GUSB", "GYG1", "GYS1", "H1F0", "H2AFX", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HEBP1", "HECTD1", "HECTD3", "HERC2", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HINT2", "HIRA", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGCL", "HMGCS1", "HMGN1", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HPRT1", "HPSE", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IFT52", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "ILF2", "ILK", "IMMT", "IMP3", "IMP4", "IMPAD1", "IMPDH2", "INCENP", "INTS1", "INTS11", "INTS12", "INTS13", "INTS14", "INTS3", "INTS4", "INTS7", "INTS9", "IPO5", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRS4", "ISCU", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITM2B", "ITM2C", "ITPA", "IVD", "IWS1", "JMJD6", "JUP", "KARS", "KAT7", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0391", "KIF11", "KIF14", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAMTOR3", "LARS", "LARS2", "LAS1L", "LBR", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LNPEP", "LONP2", "LPCAT1", "LPGAT1", "LRP1", "LRP2", "LRPPRC", "LRRC1", "LRRC8C", "LRSAM1", "LSM2", "LSM3", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LTV1", "LYN", "LYPLA1", "LZTFL1", "MAD2L1", "MAGED1", "MAGED2", "MAGT1", "MAN1A1", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP2K1", "MAP2K4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MARC1", "MARCKS", "MARK3", "MARS", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD1", "MBD3", "MBOAT7", "MCAM", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "ME1", "ME2", "MEAF6", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED21", "MED23", "MED24", "MED25", "MED4", "MEN1", "METAP1", "MFAP1", "MFN1", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MIF", "MINPP1", "MIOS", "MIPEP", "MLEC", "MMAB", "MMS19", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP5", "MPP7", "MPRIP", "MPST", "MRC2", "MRE11", "MRGBP", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL55", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTM1", "MTMR2", "MTMR6", "MTOR", "MTR", "MTX1", "MTX2", "MUT", "MYBBP1A", "MYDGF", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1C", "MYO1E", "MYO6", "NADK2", "NAE1", "NAGLU", "NAMPT", "NANS", "NAPA", "NAPG", "NARS", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCBP1", "NCK1", "NCK2", "NCKAP1", "NCKIPSD", "NCL", "NCSTN", "ND1", "NDC1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFC2", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4", "NEDD4L", "NEFL", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NEU1", "NF2", "NFRKB", "NFS1", "NHLRC2", "NHP2", "NIP7", "NIPBL", "NIPSNAP2", "NISCH", "NLN", "NLRX1", "NME1", "NME2", "NME3", "NME7", "NMT1", "NNT", "NOB1", "NOC2L", "NOC4L", "NOL11", "NOL6", "NOL9", "NOP14", "NOP2", "NOP56", "NOP58", "NOSIP", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NRBP1", "NRP1", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSMCE3", "NSUN2", "NT5C2", "NT5C3A", "NT5C3B", "NTHL1", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUDC", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NXF1", "OAT", "OCLN", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC2", "ORC3", "ORC5", "OS9", "OSBP", "OSBPL11", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD7B", "OXA1L", "P3H1", "P3H3", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAK2", "PAK4", "PANK4", "PAOX", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATJ", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCM1", "PCMT1", "PCNA", "PDAP1", "PDCD11", "PDCD4", "PDCD6", "PDCD6IP", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA5", "PDIA6", "PDK3", "PDLIM5", "PDP1", "PDPR", "PDS5A", "PDS5B", "PDSS2", "PDXK", "PDZD11", "PEBP1", "PECR", "PELP1", "PES1", "PEX14", "PEX16", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF5A", "PHF8", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGK", "PIGL", "PIGS", "PIGT", "PIK3C2A", "PIK3R4", "PIN1", "PIP4K2C", "PIR", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PKP2", "PLA2G15", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNO1", "PNP", "PNPLA6", "PNPO", "POFUT1", "POFUT2", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3F", "POLRMT", "POMGNT2", "PON2", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAT", "PPIB", "PPID", "PPIE", "PPIH", "PPIL1", "PPIL4", "PPM1F", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R2", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PRIM1", "PRIM2", "PRKAA1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF6", "PRPF8", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PTBP1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PUS1", "PUS7", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QKI", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABEP1", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RBBP5", "RBBP6", "RBFOX2", "RBM14", "RBM17", "RBM22", "RBM28", "RBM4", "RBM5", "RBM8A", "RBMX", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RDH11", "RDH13", "RDH14", "RDX", "REL", "REPS1", "RETSAT", "REXO2", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RICTOR", "RIDA", "RIF1", "RINT1", "RIOX2", "RNASET2", "RNF114", "RNF14", "RNF20", "RNF40", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS19BP1", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP8", "RRP9", "RSF1", "RSU1", "RTCB", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "RXRB", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SATB2", "SC5D", "SCAMP1", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCO1", "SCO2", "SCP2", "SCRIB", "SDCBP", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEH1L", "SEL1L", "SENP3", "SEPT2", "SEPT7", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SGPL1", "SGTA", "SH3GL1", "SHC1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIKE1", "SIN3A", "SIN3B", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A26", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC30A7", "SLC35B2", "SLC38A2", "SLC3A2", "SLC4A7", "SLC5A6", "SLC6A15", "SLC7A1", "SLIT2", "SLK", "SLTM", "SMARCA4", "SMARCA5", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMG8", "SMG9", "SMN1*", "SMNDC1", "SMPD4", "SNAP23", "SNAP29", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX2", "SNX3", "SNX5", "SNX9", "SOAT1", "SOD2", "SORD", "SORT1", "SPAG9", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPEN", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD3NL", "STARD7", "STAT1", "STIP1", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRN", "STT3A", "STUB1", "STX10", "STX18", "STX3", "STX5", "STX6", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGT1", "SUMF2", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SURF4", "SUZ12", "SV2A", "SYMPK", "SYNE2", "TAB1", "TACO1", "TAF15", "TAF4", "TAF7", "TAGLN2", "TALDO1", "TAOK3", "TAP1", "TAP2", "TARS", "TARS2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBCA", "TBCB", "TBCD", "TBCE", "TBL3", "TCEA1", "TCP1", "TDP2", "TDRKH", "TECR", "TERF2IP", "TEX10", "TEX264", "TFAM", "TFB1M", "TFG", "TFIP11", "TFRC", "THADA", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM13", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TIMM9", "TIMMDC1", "TJP1", "TJP2", "TK1", "TKT", "TLN1", "TMED10", "TMED2", "TMED5", "TMED9", "TMEM11", "TMEM30A", "TMEM59", "TMF1", "TMLHE", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMX3", "TNKS1BP1", "TNPO1", "TOM1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOPBP1", "TOR1A", "TOR1AIP1", "TOR1B", "TP53", "TP53BP1", "TP53BP2", "TPD52", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPX2", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT6", "TRMU", "TRRAP", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPO", "TSR1", "TST", "TSTA3", "TTC21B", "TTC26", "TTC37", "TTC5", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWNK", "TXLNA", "TXNDC5", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UACA", "UAP1", "UBA1", "UBA2", "UBA5", "UBA6", "UBAC1", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBQLN1", "UBR4", "UBTF", "UBXN1", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UGCG", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "UMPS", "UNC119B", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USE1", "USO1", "USP1", "USP10", 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0.0111513909797036 2.344660194174758 5.334951456310679 0.5676306621192281 0.3848598361215665 1.4772204386407015 1.028450501743625 1.1508412144445943 0.3180214528184469 0.0159916695081137 1.0 0.0100519320580488 0.0062969264366488 6.856302599535404e-05 +Overlap between signal transduction pathways contributing to lmna laminopathies 4 15 2.521666357479708 0.0116800432461696 4.927184466019417 14.766990291262136 1.2077866030529698 0.2877996039599693 1.943257907759383 1.4611731122572065 0.935661776029738 0.2919054664837305 0.4266765794809749 0.1952735388158895 0.3530974878629287 0.0045172618985585 0.0664883963333954 +Embryonic stem cell pluripotency pathways 3 13 2.488521505848219 0.0128275478774955 4.002427184466019 11.550970873786408 -0.0503246519598591 0.6004846621088701 2.51451976384282 2.062099982774233 0.8116037437092664 0.2997896522307284 0.5356473873734466 0.2588687133858448 0.4515227909961177 0.0637468602571873 0.3577940609047028 +Synaptic signaling pathways associated with autism spectrum disorder 3 13 2.415716304794832 0.0157042917364118 3.388349514563106 10.114077669902912 0.1616055074841362 0.6004388607287494 2.4681780934812103 2.5550437219648225 0.8391828914689811 0.3118788745810285 0.3669623924035387 0.1635258499471353 0.3009165941166509 0.0602711275874904 0.1040239469578102 +Nocgmppkg mediated neuroprotection 5 8 2.400698911375024 0.0163637945072585 1.7087378640776698 5.701456310679611 0.2970517947213684 0.5046271634002197 1.31924565059907 1.5981475367005755 0.915565562180938 0.2911269813556215 0.0318919308376235 0.1049896535105009 0.1993869387044997 0.1067922158236129 0.0043704316922178 +Head and neck squamous cell carcinoma 3 19 2.3731117389651595 0.017638926850952 4.456310679611651 14.725728155339803 0.1553520169571757 0.6410777678332499 3.22468241539802 3.363859636527039 0.7511771794254456 0.2963756108483184 0.5635932229677546 0.2766173679843171 0.4775398588675821 0.4877184600960113 0.4137246468241853 +Endometrial cancer 2 15 2.307971935063303 0.0210006974957401 3.936893203883495 11.968446601941748 -0.0734073994044348 0.6871490668481969 2.703988075577708 2.0695373796081213 0.6769206688887579 0.277667014205178 0.512018468451612 0.2443632781182481 0.4297892617739207 0.1668895930314442 0.542435029178986 +Relationship between inflammation cox2 and egfr 1 6 2.2816598007103304 0.0225094331535877 1.2014563106796117 4.002427184466019 0.5881028663928072 0.4915958336700311 1.024314980916553 0.966674778916386 0.8918698344853219 0.3144531725977539 0.1792312731033967 0.0742352733278267 0.1432798584585485 0.0565188023636715 0.1818418904091173 +Oxidation by cytochrome p450 3 5 2.2384455479101915 0.0251920145839004 2.3179611650485437 5.422330097087379 1.262256455948566 0.1900711291682963 1.161003800051733 0.6764315332620536 1.214909583878196 0.2447393771863318 0.0004702982027394 0.0607401038440192 0.0066572828402184 0.0033939033653995 0.0028040242445346 +Sphingolipid metabolism overview 3 9 2.233926987408688 0.0254878775183677 4.0 7.951456310679611 1.305604070038762 0.1692072490812911 2.0060587839493125 1.5113078035984122 1.4254327231792938 0.2283290755268721 0.0010788177062325 0.0786913117950012 0.0113213926532688 0.0006333985816127 0.0079931710216612 +Sphingolipid metabolism integrated pathway 3 9 2.233926987408688 0.0254878775183677 4.058252427184466 8.101941747572816 1.3056837288293504 0.1731905617886817 2.1182299017960826 1.603786816240382 1.4154175704443392 0.233855234687812 0.0015100512536669 0.0875404472016038 0.014058804472369 0.0009927961558234 0.0120515986398723 +Chromosomal and microsatellite instability in colorectal cancer 2 20 2.227007765875844 0.0259467547773102 5.351941747572815 17.347087378640776 -0.1475622240385571 0.6550617766984735 3.585965241751969 2.6673895937399466 0.7202523672758854 0.2826000438958693 0.5526209371974827 0.2695684389372801 0.4672829604777532 0.2100263434971256 0.6204077015109344 +Metabolism of spingolipids in er and golgi apparatus 3 5 2.2014226262823664 0.0277061186708034 2.1432038834951457 4.12378640776699 1.255170581651192 0.2109312980793922 1.3711229283492827 1.3022449745711573 1.2018683368625842 0.2544377197345568 0.0106465592757744 0.0607401038440192 0.1180585699575878 0.0033939033653995 0.0028040242445346 +Resistin as a regulator of inflammation 1 7 2.1715354122108 0.0298907232974456 2.337378640776699 6.084951456310679 0.0661412442998359 0.5345156089327865 1.857877722922096 2.1144594084248864 0.994615730480242 0.3154798560768314 0.2656377065204329 0.1135912525516411 0.2147385524083838 0.1227655047468798 0.3460963812051635 +Mitochondrial complex iv assembly 5 13 2.1636942503039003 0.03048782257808 4.645631067961165 11.985436893203884 1.036764412652062 0.2236438909453165 2.399566170297607 1.9080263664188637 1.5325215618909758 0.2795558816325345 0.0648502590755818 1.0 0.2802926639431586 0.0489147892655661 0.0233089974379561 +Cholesterol biosynthesis with skeletal dysplasias 4 7 2.154825038271124 0.0311755281384749 2.703883495145631 6.024271844660194 1.6250539245333766 0.1427602110791373 1.3052115351448448 0.7101163612316155 0.9675759117714408 0.205892393525391 0.0030076637467772 0.0331691185540615 0.0018609890552042 0.011414919510753 0.0001735559058557 +Melanoma 3 16 2.154092108248766 0.0312329493105498 4.538834951456311 14.359223300970871 -0.0634804098228951 0.6335583208664796 2.79492372752136 2.4419647069006394 0.7619764304492439 0.2857751103432576 0.4997605673727464 0.2370066357192962 0.4186050092003007 0.1550907391962028 0.2907029992587308 +Kisspeptinkisspeptin receptor system in the ovary 1 6 2.1438965448701417 0.032041177112865 2.2645631067961167 6.162621359223301 0.0633300359973829 0.5992713402053965 1.808933213866981 2.0468448184950647 0.8308223563430294 0.2993998188698849 0.2923845056635012 0.1263420182810564 0.2372212797486779 0.1476943407876319 0.3992856920588761 +Influence of laminopathies on wnt signaling 3 11 2.132692348243716 0.0329499720237977 2.929611650485437 10.199029126213592 1.172665957836072 0.274405530989148 1.5096443497648335 1.3031697834850824 0.8784257604250459 0.2713478851839423 0.3096765085512921 0.134742527043449 0.2518545844225215 0.0056932223374956 0.0560616912320164 +Tolllike receptor signaling pathway 1 11 2.0513427328389646 0.0402335817298642 4.441747572815534 12.20873786407767 -0.2981400059822564 0.544663513432487 2.8733804816959405 3.4026148367691085 0.8688594126060782 0.3000799199762518 0.4807987606017377 0.225839943305071 0.4014202890149608 0.3708274474010383 0.7378830318157182 +Cardiac hypertrophic response 2 13 2.0270289653610893 0.0426594505249999 4.233009708737864 11.400485436893204 -0.0639293491578199 0.6062345367851906 2.747298349871508 3.058062677115457 0.8129610160037826 0.2983635156140802 0.3975529795850857 0.1795501084992132 0.327507803675052 0.2631788935246822 0.3228304985102302 +Sphingolipid pathway 3 10 2.0210671564599605 0.0432728136769264 4.274271844660194 9.393203883495143 1.2258474538683668 0.1888473674707098 2.02173101931241 1.3620203536909472 1.3696572221543342 0.2416569853225122 0.0023364039281307 0.1006582454154426 0.018640880521655 0.0017693141021238 0.020271757680103 +Bdnftrkb signaling 5 12 2.016692858075732 0.043727575708405 2.5800970873786406 7.924757281553398 -0.2948167042200635 0.5621234341737743 1.7531918160806303 1.4653501815880017 0.8360268726247192 0.3068533777909888 1.0 1.0 1.0 0.4732445906533414 0.0355737118947821 +Wnt signaling pathway 3 14 2.003939347598231 0.0450765579426557 3.9563106796116503 12.050970873786408 -0.1668721405390101 0.6077108119526166 2.6112218582109348 2.3264673893512393 0.8231911322186768 0.2957072479206077 1.0 1.0 1.0 0.0909853548684221 0.1653068273939545 +Kennedy pathway from sphingolipids 3 6 2.0010133461952506 0.0453909516426609 1.8349514563106797 4.538834951456311 1.005685357170638 0.2842758763214292 1.1414272055653287 1.0616650240280194 1.1079123437614409 0.2814205551839854 1.0 1.0 1.0 0.0442367692127036 0.0280386150660574 diff --git a/msigdb_wp/metrics.json b/msigdb_wp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..636c94b841051f2cf634b6dcbbfff6ec94d77ae8 --- /dev/null +++ b/msigdb_wp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3381, + "annotations_size": 596, + "title": "Average number of proteins per term", + "value": 11.478187919463087 +} \ No newline at end of file diff --git a/msigdb_wp/paths.json b/msigdb_wp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..3c156fbb83e2af5b1e05de67f16522138cedfacf --- /dev/null +++ b/msigdb_wp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_wp/fragment/C317/C317_val_log2fc"} \ No newline at end of file diff --git a/msigdb_wp/result.tsv b/msigdb_wp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..8650bd99a9fb94dba6ad4e71eceddca3a5567d74 --- /dev/null +++ b/msigdb_wp/result.tsv @@ -0,0 +1,231 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Alzheimers disease and mirna effects 0.4389558758528688 2.7715618478166095 0.0055788073107867 0.9643597078001768 0.4953182298345657 88 P28072,Q9H0B6,P31751,Q08209,Q9NQC3,O95197,P28074,P20618,P28070,P31749,P33176,P21796,P25054,P49721,P45880,Q99436,P0DP25,P16615,O14641 19 +Alzheimers disease 0.4430058928949361 2.7472133994802546 0.0060104013383257 0.9724845539106012 0.4953182298345657 87 P28072,Q9H0B6,P31751,Q08209,Q9NQC3,O95197,P28074,P20618,P28070,P31749,P33176,P21796,P25054,P49721,P45880,Q99436,P0DP25,P16615,O14641 19 +Striated muscle contraction pathway 0.8695803697817827 2.5379186267634655 0.0111513909797036 0.9987486898942728 0.4953182298345657 7 P35609,P06753,P08670,P09493,P67936 5 +Overlap between signal transduction pathways contributing to lmna laminopathies 0.699400184424039 2.521666357479708 0.0116800432461696 0.99909019413094 0.4953182298345657 15 O60725,O75844,P55209,P25054 4 +Embryonic stem cell pluripotency pathways 0.7206782803649449 2.488521505848219 0.0128275478774955 0.9995447558294884 0.4953182298345657 13 P31749,P25054,P31751 3 +Synaptic signaling pathways associated with autism spectrum disorder 0.7073785726159176 2.4157163047948313 0.0157042917364118 0.9999200437291046 0.4953182298345657 13 P31749,Q05086,P31751 3 +Nocgmppkg mediated neuroprotection 0.8153847830026167 2.400698911375024 0.0163637945072585 0.9999463752290524 0.4953182298345657 8 P35609,P07196,P30536,Q99996,P16220 5 +Head and neck squamous cell carcinoma 0.6093516816556042 2.3731117389651595 0.017638926850952 0.9999752484533666 0.4953182298345657 19 P49815,P31749,P31751 3 +Endometrial cancer 0.6628183087327262 2.307971935063303 0.0210006974957401 0.9999967915158184 0.4953182298345657 15 P31749,P31751 2 +Relationship between inflammation cox2 and egfr 0.8320051310396293 2.2816598007103304 0.0225094331535877 0.9999987203397216 0.4953182298345657 6 P31751 1 +Oxidation by cytochrome p450 0.8734044571287873 2.2384455479101915 0.0251920145839004 0.999999751245703 0.4953182298345657 5 O43169,Q16850,Q6UW02 3 +Sphingolipid metabolism overview 0.7568886805744015 2.233926987408688 0.0254878775183677 0.99999979241376 0.4953182298345657 9 Q16739,Q06136,Q96G23 3 +Sphingolipid metabolism integrated pathway 0.7568886805744015 2.233926987408688 0.0254878775183677 0.99999979241376 0.4953182298345657 9 Q16739,Q06136,Q96G23 3 +Chromosomal and microsatellite instability in colorectal cancer 0.5700265027720173 2.2270077658758436 0.0259467547773102 0.9999998432210409 0.4953182298345657 20 P31749,P31751 2 +Metabolism of spingolipids in er and golgi apparatus 0.8643899134057536 2.2014226262823664 0.0277061186708034 0.9999999466245648 0.4953182298345657 5 O95470,Q16739,Q06136 3 +Resistin as a regulator of inflammation 0.786550278414611 2.1715354122108 0.0298907232974456 0.999999986032718 0.4953182298345657 7 P31751 1 +Mitochondrial complex iv assembly 0.6621919440409341 2.1636942503039003 0.03048782257808 0.9999999903228396 0.4953182298345657 13 Q9Y2R0,P00403,Q53S58,P13073,P14406 5 +Cholesterol biosynthesis with skeletal dysplasias 0.7828462700846479 2.1548250382711234 0.0311755281384749 0.9999999936601388 0.4953182298345657 7 Q14739,Q15392,Q16850,Q15125 4 +Melanoma 0.6236855927616192 2.154092108248766 0.0312329493105498 0.9999999938801868 0.4953182298345657 16 P31749,P0DP25,P31751 3 +Kisspeptinkisspeptin receptor system in the ovary 0.8002234551452503 2.1438965448701417 0.032041177112865 0.9999999962786364 0.4953182298345657 6 P31751 1 +Influence of laminopathies on wnt signaling 0.6906761904925848 2.132692348243716 0.0329499720237977 0.9999999978739704 0.4953182298345657 11 O75844,O60725,P25054 3 +Tolllike receptor signaling pathway 0.6753532490699264 2.0513427328389646 0.0402335817298642 0.9999999999765216 0.4953182298345657 11 P31751 1 +Cardiac hypertrophic response 0.6382136724638644 2.0270289653610893 0.0426594505249999 0.9999999999948048 0.4953182298345657 13 P31749,P31751 2 +Sphingolipid pathway 0.6918710450260541 2.0210671564599605 0.0432728136769264 0.9999999999964542 0.4953182298345657 10 Q16739,Q06136,Q96G23 3 +Bdnftrkb signaling 0.6458892306465571 2.016692858075732 0.043727575708405 0.9999999999973292 0.4953182298345657 12 P31749,Q15418,P49815,P62993,P16220 5 +Wnt signaling pathway 0.6237392001262009 2.003939347598231 0.0450765579426557 0.9999999999988484 0.4953182298345657 14 O14641,P25054,P31749 3 +Kennedy pathway from sphingolipids 0.7677679239562167 2.0010133461952506 0.0453909516426609 0.9999999999990538 0.4953182298345657 6 O95470,Q9HBU6,P35790 3 +Translation inhibitors in chronically activated pdgfra cells 0.5331346460378351 1.958656148623087 0.0501530691774767 0.999999999999952 0.4953182298345657 20 P31749,Q15418,Q14240,P31751 4 +Proteoglycan biosynthesis 0.8581581285164305 1.9501651537704496 0.0511564376319224 0.9999999999999744 0.4953182298345657 4 Q8NCH0,Q9NX62,Q8TB61 3 +Camkk2 pathway 0.6248546991077994 1.9500180334303208 0.05117396968711 0.9999999999999748 0.4953182298345657 13 O00429,P09601,P16220 3 +Nrp1triggered signaling pathways in pancreatic cancer 0.6297500089297522 1.925999745622144 0.0541044056078885 0.999999999999996 0.4953182298345657 12 P31751 1 +Nanomaterial induced apoptosis 0.7954640209142019 1.9134580984171736 0.055689432798663 0.9999999999999986 0.4953182298345657 5 O95831,Q9NR28 2 +Tcell activation sarscov2 0.5854018001226147 1.9132510342113491 0.0557159229951889 0.9999999999999986 0.4953182298345657 16 P31749,P49841,Q15382,O15111,P49815,P62993,Q07812 7 +Tgfbeta signaling in thyroid cells for epithelialmesenchymal transition 0.7945470507139197 1.909570518150102 0.0561885340815759 0.9999999999999988 0.4953182298345657 5 P08670 1 +Tnfrelated weak inducer of apoptosis tweak signaling pathway 0.6697860966811792 1.90706000069479 0.0565128181690444 0.9999999999999992 0.4953182298345657 10 P31751 1 +Transcription factors regulate mirnas related to cardiac hypertrophy 0.9401368856953404 1.899536501861257 0.0574939720366602 0.9999999999999996 0.4966145990412975 3 P31751 1 +Vitamin a and carotenoid metabolism 0.7435614217785824 1.8930339746806424 0.0583533514751697 0.9999999999999998 0.4968371068457309 6 O94788,Q8WTV0 2 +Photodynamic therapyinduced nfe2l2 nrf2 survival signaling 0.8372839441408395 1.8660100498549783 0.062039959452711 1.0 0.5034114758916068 4 P09601 1 +Cell migration and invasion through p75ntr 0.7835185067796429 1.8627026743401935 0.0625041094227834 1.0 0.5034114758916068 5 P31751 1 +Sphingolipid metabolism in senescence 0.6158164739138765 1.847015991285783 0.0647448226863165 1.0 0.5145055242805954 12 Q16739,Q96G23 2 +Nitric oxide metabolism in cystic fibrosis 0.8296632140007942 1.83513301764586 0.0664859828116584 1.0 0.5213900757335317 4 O60678 1 +Mitochondrial complex iii assembly 0.6310003531186783 1.8118628674490929 0.0700073881885454 1.0 0.5361847206518655 11 Q9UDW1,P22695,O14949 3 +Ccl18 signaling pathway 0.6710528235098575 1.810799938480006 0.0701718258571233 1.0 0.5361847206518655 9 P08670,P07196,P00403,P33176 4 +Endothelin pathways 0.7011399964762466 1.7784831123240616 0.0753245431344078 1.0 0.560016612357888 7 P16615,P42892,P00403 3 +Amyotrophic lateral sclerosis als 0.6230119524246197 1.7681173894158615 0.077041280909184 1.0 0.560016612357888 11 P07197,P07196 2 +Neural crest cell migration during development 0.6780928503717115 1.7531108334525878 0.0795829843306576 1.0 0.560016612357888 8 P31751 1 +Regulation of apoptosis by parathyroid hormonerelated protein 0.7562203791469128 1.7458391948296903 0.0808388981319538 1.0 0.560016612357888 5 P49841,Q07820,Q9BXK5,P31749 4 +Nonsmall cell lung cancer 0.5696128505477609 1.7401335618979683 0.0818355682629676 1.0 0.560016612357888 15 P31751 1 +Neural crest cell migration in cancer 0.6569714615991293 1.7396257072264287 0.0819247622319292 1.0 0.560016612357888 9 P31751 1 +Disruption of postsynaptic signaling by cnv 0.6564510941413408 1.7369866365203357 0.0823895296895507 1.0 0.560016612357888 9 Q06787,Q13555,Q7L576,P27361,Q14168 5 +Familial partial lipodystrophy fpld 0.6890468171456952 1.7215854591592024 0.0851446391121937 1.0 0.560016612357888 7 O60725,P31751 2 +Intracellular trafficking proteins involved in cmt neuropathy 0.5938956265593872 1.7215115328020605 0.0851580412396497 1.0 0.560016612357888 12 O60333,Q9NR77,P07196,P50570 4 +Electron transport chain oxphos system in mitochondria 0.478546629120635 1.719596063909409 0.0855058921553151 1.0 0.560016612357888 53 P00846,O75964,Q9UDW1,P22695,P00403,P56556,P03886,O14949,P06576,O96000,P13073,O43676,P14406 13 +Micrornas in cardiomyocyte hypertrophy 0.4990134887188744 1.704226022574182 0.0883388693974562 1.0 0.571861224968178 20 Q08209,P31749,P49841,P31751,O75116 5 +Genes related to primary cilium development based on crispr 0.5631318648617913 1.6994555706974266 0.0892333790638264 1.0 0.571861224968178 15 Q7Z4L5,Q8WXW3,O95684,Q8NCM8,Q10713 5 +Mecp2 and associated rett syndrome 0.4981431897369389 1.6852636086917892 0.0919377235498635 1.0 0.5767882445865122 23 P67809,P31749,Q05086,P35637,P52597,P16220,Q03518 7 +Pi3kaktmtor signaling pathway and therapeutic opportunities 0.6789133019037695 1.6736906431804306 0.0941914136514481 1.0 0.5788060626567595 7 P49815,P31749,P49841 3 +Metapathway biotransformation phase i and ii 0.4961515332767037 1.673638547640178 0.0942016578484994 1.0 0.5788060626567595 22 Q8NCH0,Q6UW02,Q16850,P78417 4 +Triacylglyceride synthesis 0.878878913405901 1.6624336498872545 0.0964258566016624 1.0 0.5805031367130387 3 Q9HCL2 1 +Erk pathway in huntingtons disease 0.775502492942468 1.613535868794402 0.1066281370293333 1.0 0.5995317893347424 4 P42858 1 +Spinal cord injury 0.4844219842747642 1.5885367515354123 0.1121650174169601 1.0 0.6083241916057821 21 P62942,Q08209,P08670,Q9NQC3,O75116,P14174 6 +T cell receptor and costimulatory signaling 0.7148357931883305 1.566559318183421 0.11721773318686 1.0 0.6182457431802528 5 Q08209,P31749 2 +Extracellular vesiclemediated signaling in recipient cells 0.6698832839185835 1.5575605128262118 0.1193374653589081 1.0 0.6228900671042269 6 P31749 1 +Ranklrank signaling pathway 0.5295768288719971 1.5519606662871188 0.1206716354545938 1.0 0.6228900671042269 16 P31749,P31751 2 +Myometrial relaxation and contraction pathways 0.4745555659015169 1.512966264468545 0.1302882282865516 1.0 0.6541314013002807 21 P16615,P78417,P0DP25 3 +Pancreatic adenocarcinoma pathway 0.4750416237689983 1.5117134594934063 0.1306067730784117 1.0 0.6541314013002807 22 P31751 1 +Estrogen receptor pathway 0.9689257176679492 1.483344450031039 0.1379829182010961 1.0 0.6717359146515984 2 Q9HCL2 1 +Reninangiotensinaldosterone system raas 0.7434535287116064 1.4809118572865525 0.1386300629230648 1.0 0.6717359146515984 4 P0DP25,P16220 2 +Regulation of wnt bcatenin signaling by small molecule compounds 0.6513666652409403 1.4718628417819664 0.1410579195879118 1.0 0.6725641605951634 6 P25054 1 +Wntbetacatenin signaling pathway in leukemia 0.6462213669635484 1.4479705036662105 0.1476253000209983 1.0 0.6791765831286963 6 P31749 1 +Acquired partial lipodystrophy barraquersimons syndrome 0.7334912644358809 1.4395171093891432 0.1500040659523867 1.0 0.6791765831286963 4 P02545,O60725,Q03252 3 +Il7 signaling pathway 0.6442135033063696 1.438638418085848 0.1502529955017082 1.0 0.6791765831286963 6 P49841,P31749 2 +Small cell lung cancer 0.5384510129121496 1.438043685718075 0.1504216593506508 1.0 0.6791765831286963 13 P31749,P31751,P07942,O15111,P11802 5 +Caloric restriction and aging 0.6791614699503383 1.41035621246175 0.1584345279687942 1.0 0.7069208367672793 5 P31749 1 +Egfr tyrosine kinase inhibitor resistance 0.516937877121954 1.4057175802275967 0.1598080044775254 1.0 0.7069208367672793 15 P31751 1 +Breast cancer pathway 0.4635938873326876 1.4046523344095192 0.1601246861805079 1.0 0.7069208367672793 27 P31749,P25054,P31751 3 +Cholesterol metabolism with bloch and kandutschrussell pathways 0.4608562382203351 1.3925948463733928 0.1637423423393182 1.0 0.7166699446944678 24 P48449,Q16850,Q15125,Q9BWD1,Q15800,Q15392,Q14739 7 +Tnfalpha signaling pathway 0.4585119034073207 1.3893120213098469 0.1647378899717149 1.0 0.7166699446944678 21 P31749,Q9NR28,Q6GQQ9,P27361,Q16543,P06737,O15111,P62993,Q9Y297,Q07812,Q13200 11 +Mfap5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement 0.6185528519112066 1.3848481300885114 0.1660989103588876 1.0 0.717138224343335 7 P16220 1 +Physicochemical features and toxicityassociated pathways 0.4588123665744178 1.3810314276380562 0.167269297755473 1.0 0.717138224343335 23 P07197,P07196,P31749 3 +S1p receptor signal transduction 0.6002037962503552 1.3675448722893917 0.171454582377537 1.0 0.717138224343335 8 P31751 1 +Neural crest differentiation 0.5658400353782229 1.3541205550468502 0.1756979193793304 1.0 0.7172326023978146 10 Q9NR77 1 +Nad metabolism 0.7097599404209147 1.3406873314637762 0.1800219894120935 1.0 0.7298850727184202 4 Q8IXJ6 1 +Hostpathogen interaction of human coronaviruses apoptosis 0.7050072384275656 1.3208687247443718 0.1865451395815522 1.0 0.7437707752332517 4 Q07820,P31749 2 +Aryl hydrocarbon receptor pathway wp2586 0.6036560083043454 1.312831450703407 0.1892397496921765 1.0 0.746933051765147 7 P07900,P00533,Q16543,O00170,P24941 5 +Nonalcoholic fatty liver disease 0.4348337663205244 1.2939645622751126 0.1956776618021247 1.0 0.749826301722177 52 P31749,P31751,Q9UDW1,P22695,P00403,O14949,O96000,O43676,Q86Y39,P14406 10 +Nad biosynthetic pathways 0.6525009344145962 1.2929496825841804 0.1960284625406676 1.0 0.749826301722177 5 Q8IXJ6 1 +Vitamin dsensitive calcium signaling in depression 0.6523058321248332 1.2920892118635543 0.1963262514853871 1.0 0.749826301722177 5 Q8NB78,O60341,P11413 3 +Hepatitis b infection 0.4470028876440874 1.2886454986969718 0.1975213580039962 1.0 0.749826301722177 23 P31749,P31751 2 +Riboflavin and coq disorders 0.6088964311700575 1.273860846403051 0.2027127365634942 1.0 0.7551049436990159 6 Q8NI60,O75208 2 +Glycerolipids and glycerophospholipids 0.5896342203955662 1.2448861603384789 0.2131735988205014 1.0 0.7854596418222027 7 Q9HBU6,Q9HCL2 2 +15q112 copy number variation syndrome 0.6853901469618078 1.2390348078024165 0.2153326078558706 1.0 0.7854596418222027 4 Q7L576,Q9BSJ2 2 +Omega3 omega6 fatty acid synthesis 0.6001035611227508 1.2327056582570357 0.2176856000333531 1.0 0.7854596418222027 6 Q15067 1 +Angiopoietinlike protein 8 regulatory pathway 0.4430459815926892 1.2325588840102053 0.217740384854016 1.0 0.7854596418222027 32 P31749,P51812,P31751,P49841,P49815,Q15382,Q15418,P13807 8 +Complement and coagulation cascades 0.7685942208211569 1.2298081364275413 0.2187689606417544 1.0 0.7854596418222027 3 P10909 1 +Glioblastoma signaling pathways 0.4351280556157435 1.2147346775240282 0.224467301962187 1.0 0.7987488117798975 20 P31749,P31751 2 +Il17 signaling pathway 0.6750926921512512 1.196090027082242 0.2316614290043852 1.0 0.8072579924084619 4 P49841,P31749 2 +Cellular proteostasis 0.6696774552678528 1.1735192360336415 0.2405876475386295 1.0 0.8078060896359848 4 O15212 1 +Arrhythmogenic right ventricular cardiomyopathy 0.4801696042739309 1.1683444308874449 0.2426678600712244 1.0 0.8078060896359848 15 P35609,P16615,P50402,P12814 4 +Wnt signaling 0.4796117581775382 1.1647295346957516 0.2441284898775557 1.0 0.8078060896359848 15 Q08209,P25054,Q13555,O14641,O75116 5 +Follicle stimulating hormone fsh signaling pathway 0.5219665570132941 1.115201014982425 0.2647642912318508 1.0 0.848384503087006 10 P16220,P31749 2 +Estrogen signaling pathway 0.5615348141746247 1.1085355197432751 0.2676306079097559 1.0 0.851484935261506 7 P31749 1 +Apoptosis 0.4993395493128822 1.0728207843002244 0.2833515335170899 1.0 0.851484935261506 11 O15111,Q07820,Q9NR28,P31749 4 +Histone modifications 0.5268913827956936 1.0654946392419822 0.2866521502034884 1.0 0.851484935261506 9 Q03164,Q01105 2 +Primary focal segmental glomerulosclerosis fsgs 0.415515481616559 1.0549047752531315 0.291468878078456 1.0 0.851484935261506 21 P35579,P08670,P31749 3 +Pregnane x receptor pathway 0.6405093278057383 1.0522719072040605 0.2926748167542117 1.0 0.851484935261506 4 Q99615,P08183,P62195 3 +Complement system in neuronal development and plasticity 0.4748605142975474 1.0503737181468746 0.2935463242080238 1.0 0.851484935261506 13 O43464,Q9NR28,P10909 3 +Progeriaassociated lipodystrophy 0.5236273943187092 1.0484140055607265 0.2944479035291016 1.0 0.851484935261506 9 O75844,O60725 2 +Tgfbeta receptor signaling in skeletal dysplasias 0.638115629237982 1.042357789661394 0.2972458286598236 1.0 0.851484935261506 4 P62942 1 +Tgfbeta receptor signaling 0.638115629237982 1.042357789661394 0.2972458286598236 1.0 0.851484935261506 4 P62942 1 +Mammary gland development pathway pregnancy and lactation stage 3 of 4 0.5588156058929887 1.0394592645759313 0.2985911937410315 1.0 0.851484935261506 6 O15111,P00533,P06753,P61201 4 +Dna damage response only atm dependent 0.4117864252878261 1.0258406466455403 0.3049667032880703 1.0 0.8574762111858659 21 P31749,P25054,P31751 3 +Neuroinflammation 0.6326723219350793 1.0198405651652334 0.3078040810809819 1.0 0.8574762111858659 4 P00403 1 +Il9 signaling pathway 0.5520988971619728 1.008114728813975 0.3133993875551297 1.0 0.864660776074029 6 P50750,P62993,P27361 3 +Copper homeostasis 0.5154561162450597 1.0056901411994672 0.3145646471005723 1.0 0.864660776074029 9 O75880,P25054,P31749 3 +Apoptosis modulation and signaling 0.4718155907159193 1.0019369643956784 0.3163740383392488 1.0 0.864660776074029 12 O43464,O95831,Q9NR28 3 +Ciliopathies 0.4064518803021308 0.9842910998150908 0.3249724043233302 1.0 0.8763961673154064 21 Q7Z4L5,Q9UBB4,Q15555,Q8WXW3,Q8NCM8,Q10713 6 +Pi3kakt signaling pathway 0.4100656171093609 0.979992012030784 0.3270900616840437 1.0 0.878133679115721 43 P23588,P31751,Q15382,P07942,P11802,Q07820,P31749,P30154,Q9UBI6,Q16513,O15111,P13807,P27361,P30153,P49841,P16220,Q16543,P49815,P62993 19 +Serotonin receptor 467 and nr3c signaling 0.6205399957707207 0.9698127511130544 0.3321398358043765 1.0 0.879801520619593 4 P16220 1 +Proteasome degradation 0.4057692225668349 0.9373178199655684 0.3485950992265161 1.0 0.9088836965271806 42 P28072,P28070,O00231,Q99436,P51665,P28074,P20618,Q9UL46,P49721,P61289,Q06323 11 +Acute viral myocarditis 0.446178969321421 0.9078973239602876 0.36393247160366 1.0 0.9126198825796068 14 Q9NRG0,P31749,P49841,Q04637,P16220,Q07812 6 +Mammalian disorder of sexual development 0.6840923312402367 0.9020968017625152 0.3670054476841073 1.0 0.9126198825796068 3 O43251 1 +Epo receptor signaling 0.518789788350725 0.9020194564072916 0.3670465323409748 1.0 0.9126198825796068 7 P62993,P31749 2 +Regulatory circuits of the stat3 signaling pathway 0.46897382617719 0.9002986777785605 0.3679613245546118 1.0 0.9126198825796068 11 P16949 1 +Interleukin11 signaling pathway 0.4495103073472274 0.8956335913792846 0.3704484888820363 1.0 0.9126198825796068 13 P31749,Q15418,O15111,P62993,P16220 5 +Pi3kaktmtor vitd3 signaling 0.5245773788390999 0.8803974918508514 0.3786440147726164 1.0 0.9132873442466898 6 P49815,P31749 2 +Mthfr deficiency 0.5112565817387495 0.8659410649684651 0.3865224819696644 1.0 0.9201893625486413 7 P21964,P35790 2 +Met in type 1 papillary renal cell carcinoma 0.3991752229089588 0.8558479727588207 0.3920818759862432 1.0 0.9201893625486413 19 P31751 1 +Interactions between loxl4 and oxidative stress pathway 0.5912185712326865 0.8501366414009968 0.3952491221685439 1.0 0.9201893625486413 4 Q16543,Q8TAG9 2 +Nephrotic syndrome 0.4112503281607022 0.8145900001558515 0.4153070363414572 1.0 0.9413530187483128 17 Q7Z4L5,O75844,P35579,O43707 4 +Oxidative phosphorylation 0.3906632065527927 0.8020181687373954 0.4225424485133744 1.0 0.9413530187483128 32 P00846,O75964,P56556,P03886,O96000,Q86Y39 6 +4hydroxytamoxifen dexamethasone and retinoic acids regulation of p27 expression 0.4864941591898987 0.7975783333772857 0.4251152285096968 1.0 0.9413530187483128 8 Q96KB5,P31749 2 +Methionine de novo and salvage pathway 0.4966810293159497 0.7965861350267868 0.4256914324296585 1.0 0.9413530187483128 7 Q13126,Q9BV57 2 +Erbb signaling pathway 0.3820321792917392 0.795095647952553 0.4265578660435349 1.0 0.9413530187483128 21 P31751 1 +Osteopontin signaling 0.5772127704416921 0.7937997949275667 0.4273119920673136 1.0 0.9413530187483128 4 O15111,P27361 2 +Mfap5mediated ovarian cancer cell motility and invasiveness 0.5728786157886657 0.7765014763151704 0.4374529494669015 1.0 0.9416668261869952 4 P16220 1 +Adipogenesis 0.4248742433384762 0.7752099213695586 0.4382156265660066 1.0 0.9416668261869952 14 Q9NZ45,P02545,O75844,P16220,P43490,P14174 6 +Integrinmediated cell adhesion 0.3822844470107024 0.7739338130998896 0.4389699325821308 1.0 0.9416668261869952 24 P31751 1 +Vitamin d receptor pathway 0.4306778175355905 0.7587503178087723 0.4480019305693896 1.0 0.947952876368156 12 P11413,P20020,P49427,Q92604,P09493,P24941,Q96KA5 7 +Insulin signaling 0.3827573130775229 0.7539004020936243 0.4509090291409239 1.0 0.947952876368156 46 P31749,P31751,P51812,P33176,Q6ZWJ1,Q15382,P49841,O00159,P49815,P46976,Q15418,P13807,P62993,P10586 14 +Envelope proteins and their potential roles in edmd physiopathology 0.4015252059128621 0.7483225464185641 0.4542656281910202 1.0 0.947952876368156 17 Q9BTV4,P33176,O94901,P50402,Q14739,Q8WXH0,P62993 7 +Mapk cascade 0.4810314167160657 0.7229695269952324 0.4696986061474901 1.0 0.9631858680858486 7 P45985,Q9UHA4,P62993,P28482,P27361,Q02750 6 +Mirna regulation of prostate cancer signaling pathways 0.4785218692409324 0.711263385847546 0.4769210361112903 1.0 0.9631858680858486 7 P49841 1 +Ovarian infertility 0.7638354542764162 0.705425654758159 0.4805453832390474 1.0 0.9631858680858486 2 Q8WXH0 1 +Serotonin and anxiety 0.763243563184377 0.7033558849579261 0.4818339915052436 1.0 0.9631858680858486 2 Q08209 1 +Matrix metalloproteinases 0.7614678899082596 0.6971573084167259 0.4857043527841829 1.0 0.9631858680858486 2 Q9UGU0 1 +Supression of hmgb1 mediated inflammation by thbd 0.7564368156259278 0.6796838382122227 0.4967046715840819 1.0 0.9631858680858486 2 P09429 1 +Nodlike receptor nlr signaling pathway 0.7564368156259279 0.6796838382122227 0.4967046715840819 1.0 0.9631858680858486 2 Q96RT1 1 +Leptininsulin signaling overlap 0.7561408700799086 0.6786601689706108 0.4973532092384007 1.0 0.9631858680858486 2 P31749 1 +Translation factors 0.3764653207554627 0.6776156897228466 0.4980153954547022 1.0 0.9631858680858486 37 P23588,P55010,O75153,Q9H074,P29692,Q14240,O15372 7 +Ebsteinbarr virus lmp1 signaling 0.6228537596210861 0.6754815735866267 0.4993698544270473 1.0 0.9631858680858486 3 O15111,P07900 2 +Tca cycle nutrient use and invasiveness of ovarian cancer 0.6228537596210808 0.6754815735866082 0.499369854427059 1.0 0.9631858680858486 3 P00533,P27361 2 +Photodynamic therapyinduced ap1 survival signaling 0.4486951364175313 0.662389069346137 0.5077219071187535 1.0 0.964523368705846 9 P07900,P04637,P45985,Q07820,P20248,P00533,Q07812,Q16539 8 +G1 to s cell cycle control 0.3703687210712983 0.6617133783380461 0.5081549291503953 1.0 0.964523368705846 27 P33991,Q9Y619,P25205,O75419,P33993,Q14566,P06493,Q9UBD5,P16220,P24941,Q13416,P11802 12 +Purine metabolism and related disorders 0.4050308153395922 0.628984078576013 0.5293594796706702 1.0 0.9843335578612448 13 P00813 1 +Sulfation biotransformation reaction 0.6079299057719145 0.6227391696280979 0.5334559382368826 1.0 0.9843335578612448 3 P11413 1 +Ncrnas involved in wnt signaling in hepatocellular carcinoma 0.3975673447882739 0.585411883114714 0.5582708004755474 1.0 0.9986330640024844 13 O14641,P25054,Q86UE4 3 +Tolllike receptor signaling related to myd88 0.5953226761397363 0.5791774368823991 0.5624694536479875 1.0 1.0 3 O15111,P28482 2 +Lipid metabolism pathway 0.4097667755165941 0.5723447930999942 0.5670884091545809 1.0 1.0 11 P31751 1 +Apoptosisrelated network due to altered notch3 in ovarian cancer 0.3848177621701537 0.5594088438615159 0.5758827270477425 1.0 1.0 15 P08670,P31749 2 +Glycogen synthesis and degradation 0.3761527980892696 0.5386636070367616 0.5901189894846173 1.0 1.0 16 P52789,P30154,P0DP25,P46976,P13807 5 +Kallmann syndrome 0.5080417915621396 0.5285765856548018 0.5970992064298484 1.0 1.0 4 P31749 1 +3q29 copy number variation syndrome 0.3811818947224669 0.5112330263712161 0.609187895318565 1.0 1.0 14 O95684 1 +Glycerophospholipid biosynthetic pathway 0.4259603053065463 0.5089875089679595 0.6107609796164108 1.0 1.0 8 Q9HCL2 1 +Hostpathogen interaction of human coronaviruses mapk signaling 0.4252506158738648 0.5057594026486337 0.6130255614015514 1.0 1.0 8 P51812,Q15418 2 +Target of rapamycin tor signaling 0.3827148581714903 0.5002393399911806 0.616906560912565 1.0 1.0 13 P49815,P31749 2 +16p112 proximal deletion syndrome 0.3480143398520106 0.4974551390857891 0.6188681306216628 1.0 1.0 26 P49368,P78371,P78318,Q6IN85,Q16204 5 +Epithelial to mesenchymal transition in colorectal cancer 0.3452362610047612 0.4767768261587152 0.6335210491808789 1.0 1.0 26 P31749,P49841,P31751,Q16625,Q8N3R9 5 +Bladder cancer 0.4603080568720243 0.4766034102137211 0.6336445545867198 1.0 1.0 5 P00533,P28482,Q02750,P11802 4 +Chemokine signaling pathway 0.3418432424428436 0.475356977832287 0.6345325536423263 1.0 1.0 23 P31751 1 +Praderwilli and angelman syndrome 0.4061702472140118 0.4563293927951272 0.6481531307156065 1.0 1.0 9 Q7L576,Q05086,Q15154 3 +Melatonin metabolism and effects 0.5523514450182829 0.4390040478453134 0.6606586033098361 1.0 1.0 3 P42892 1 +Nanoparticlemediated activation of receptor signaling 0.4164196799051591 0.4347899353467595 0.6637149110587817 1.0 1.0 7 P00533,Q9Y490,P62993,P28482,Q16539,Q02750 6 +Ferroptosis 0.3347167247947881 0.4238580242738176 0.6716693583453455 1.0 1.0 23 P09601,Q9UKU0,P16435,P45880 4 +Bmp signaling in eyelid development 0.675051790470558 0.4198713879243069 0.6745794106148542 1.0 1.0 2 P27361 1 +Folatealcohol and cancer pathway hypotheses 0.5409530284248535 0.4043582558375739 0.6859492923526038 1.0 1.0 3 P16220 1 +Heme biosynthesis 0.4400870086009275 0.4019292853829192 0.6877360694235595 1.0 1.0 5 P06132 1 +Rac1pak1p38mmp2 pathway 0.346637593215313 0.3902048155985027 0.6963851009839719 1.0 1.0 17 P16949,P31749,P43246,O15111,P62993,Q07812 6 +Serotonin receptor 2 and elksrfgata4 signaling 0.5359670369216653 0.3895829896105103 0.6968449325665338 1.0 1.0 3 P27361 1 +Burn wound healing 0.3875396540257921 0.3717587788277133 0.7100724571787542 1.0 1.0 9 P08670 1 +Il1 signaling pathway 0.3553589335164031 0.3647178153511374 0.7153220586231857 1.0 1.0 14 O15111,Q13501,Q9BQ95,P31749 4 +Circadian rhythm genes 0.3361090692988657 0.3533307118224768 0.7238405237545336 1.0 1.0 47 Q8N163,Q05086,Q9UNS1,Q03164,Q8WXF1,P23246,P16220,O75116,Q9Y297,Q15233,P00813,P43490,O15294 13 +Factors and pathways affecting insulinlike growth factor igf1akt signaling 0.3732402346623391 0.3424880195117369 0.7319836585162773 1.0 1.0 10 P49770,P31749 2 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signaling pathway 0.3411414617504973 0.2773831283878664 0.7814859351515975 1.0 1.0 13 P31749 1 +Cohesin complex cornelia de lange syndrome 0.3111725630434194 0.2464650762064696 0.8053222358665191 1.0 1.0 19 P25054,P30154,Q9UQE7,P06493 4 +Thyroid stimulating hormone tsh signaling pathway 0.316155830867487 0.2409245967915792 0.809613558070915 1.0 1.0 18 P16220,P31749 2 +Inhibition of exosome biogenesis and secretion by manumycin a in crpc cells 0.3611584191261231 0.2390570855341776 0.8110613178395396 1.0 1.0 8 O14964,P31943,P27361 3 +Il5 signaling pathway 0.3340826215405625 0.2370605319617175 0.8126098306184062 1.0 1.0 12 P31749,Q15418,P49841 3 +16p112 distal deletion syndrome 0.3565500889152362 0.2081318631092732 0.8351260087227586 1.0 1.0 7 Q9H2V7,P49411,P20339,Q99873,P20338,P62993 6 +Tcell antigen receptor tcr pathway during staphylococcus aureus infection 0.3160851173760255 0.1757686281231037 0.8604757170128821 1.0 1.0 15 P31749,P49841,O15111,P62993,P27361,P11802 6 +Cholesterol biosynthesis pathway 0.3201736613007769 0.1741275324572977 0.8617652359486911 1.0 1.0 12 P48449,Q16850,Q15800 3 +Microtubule cytoskeleton regulation 0.2982234532770024 0.1702214677867789 0.8648359692402483 1.0 1.0 19 P25054,P31749 2 +Focal adhesion pi3kaktmtorsignaling pathway 0.311165511337345 0.1574091815572336 0.8749223778265969 1.0 1.0 43 P23588,P31749,P31751,P49841,P49815,P30154,Q15382,Q9UBI6,P07942,Q16543,P13807,P62993,P16220 13 +Gdnfret signaling axis 0.4328004736530476 0.1467944600590025 0.8832942575465306 1.0 1.0 3 P35222,Q9BW83 2 +Lncrna in canonical wnt signaling and colorectal cancer 0.3016677790043798 0.1370934080463211 0.8909569628902958 1.0 1.0 17 O14641,P25054 2 +Tcell receptor tcr signaling pathway 0.2874975566709885 0.1338938946396522 0.8934864781861005 1.0 1.0 21 P08670,P31749 2 +Malignant pleural mesothelioma 0.2855019702311337 0.130544702550522 0.8961354891946378 1.0 1.0 72 P23588,P31751,Q15382,P07942,Q9Y297,P11802,Q07820,P31749,P51812,Q04637,Q13257,O15294,P49841,P25054,Q15047,P16220,P49815,P62993,O14641,P09429,Q15418 21 +Map3k1 role in promoting and blocking gonadal determination 0.343898104265389 0.1193621997140492 0.9049884074042908 1.0 1.0 5 P35222,P28482,Q13464,P49841 4 +Wnt signaling pathway and pluripotency 0.2936846338079588 0.1180904745570071 0.9059959708431002 1.0 1.0 18 O14641,P25054 2 +Calcium regulation in cardiac cells 0.2904003438440922 0.1155325659950695 0.9080230093604152 1.0 1.0 25 Q14012,P62942,Q04917,P05026,P20020,Q9UBI6,Q13555,P0DP25,P16615,P31946,Q9Y3B8,P10644,P63104 13 +Sting pathway in kawasakilike disease and covid19 0.4100059206631147 0.1114157840271956 0.9112866441437896 1.0 1.0 3 O15111,Q04864 2 +Sterol regulatory elementbinding proteins srebp signaling 0.2969056492330916 0.1046543573907243 0.916650080522862 1.0 1.0 32 P48449,Q16850,Q9NR31,P31749,Q9HCL2,P16220,Q15437,Q8WTV0 8 +Ppar signaling pathway 0.2816515127863168 0.1009148491046528 0.9196180554038362 1.0 1.0 21 Q15067,Q9UKU0 2 +Mapk signaling pathway 0.2993074898446761 0.086333630378061 0.9312012050935364 1.0 1.0 39 P16949,P31749,Q9Y4G8,P31751,Q9H2K8 5 +Nucleotide metabolism 0.3030018865784394 0.0827777788919636 0.9340282383518204 1.0 1.0 11 P31350 1 +Ethanol effects on histone modifications 0.2950006722815181 0.0726502801018638 0.9420844146641516 1.0 1.0 12 O94788,P00374 2 +Pdgfrbeta pathway 0.3083308627334683 0.0718427763279461 0.942727030165068 1.0 1.0 8 P45985,P19174,P19525,P42224,P62993,P27361,Q02750 7 +Nuclear receptors in lipid metabolism and toxicity 0.4844628588339823 0.0701084159780742 0.9441073682055248 1.0 1.0 2 P08183 1 +Peroxiredoxin 2 induced ovarian failure 0.3611604499703906 0.0577237728210693 0.9539686572925852 1.0 1.0 3 Q9UGN5,Q07812 2 +Inclusion body myositis 0.3573120189461224 0.0546672810064475 0.9564035363409364 1.0 1.0 3 P05067,Q92542 2 +Lncrnamediated mechanisms of therapeutic resistance 0.4598993785143595 0.0537071373586005 0.9571684962214506 1.0 1.0 2 P08183 1 +Proximal tubule transport 0.2981919719025734 0.0486614494410998 0.961189098348258 1.0 1.0 9 Q9UI12,Q9Y5K8,P05023 3 +Liver x receptor pathway 0.4477656111275583 0.0474131932562296 0.9621839141485268 1.0 1.0 2 O00767 1 +Ciliary landscape 0.2503865150220682 0.0324121305473961 0.9741433887935552 1.0 1.0 108 P07197,Q13409,Q9Y4W6,Q96P70,Q9Y266,P42704,Q9NTJ3,O15173,O95721,Q9UBW8,Q99567,Q9NVA1,O43464,Q99627,P61201,P25054,P08670,P51665,O43805,Q13868,P60660,Q8IUR7,Q9BT78,P33991,Q8TAG9,P07196,Q96A65,Q15555,A0AVF1,P43246 30 +Disorders of folate metabolism and transport 0.291220428090523 0.0308001922057845 0.97542888713589 1.0 1.0 8 P00374 1 +Mirna regulation of p53 pathway in prostate cancer 0.2936803887659288 0.0280047741447757 0.9776583434246682 1.0 1.0 4 O14681 1 +Mapk pathway in congenital thyroid cancer 0.3078744819419741 0.0276903952831525 0.9779090842214804 1.0 1.0 3 P27361,Q02750 2 +Eicosanoid synthesis 0.3749630068067574 0.0275638840345687 0.978009987078578 1.0 1.0 2 Q9H7Z7 1 +Retinoblastoma gene in cancer 0.2924563977849002 0.0242705159056431 0.9806368310995656 1.0 1.0 47 P20248,Q14527,Q9Y619,P16949,P31350,O75419,P33993,P25205,Q14566,P00374,P06493,P26583,P09429,Q16204,P40937,Q9UQE7,P33991,P11802 18 +Mitochondrial complex i assembly model oxphos system 0.2816203708026471 0.0222714142460458 0.9822314513517296 1.0 1.0 31 Q7L592,O95168,O75306,Q9NPL8,Q9BQ95,O43674,P56556,P03886,O96000,O43676,Q96CU9 11 +Oxidative damage response 0.2802132701421753 0.0167407595642344 0.9866434302803556 1.0 1.0 5 P60953,P45985,O95551,O95429 4 +Signal transduction through il1r 0.2642535423384115 0.0089619204862361 0.9928495177253956 1.0 1.0 4 Q9BQ95 1 diff --git a/msigdb_wp/selections.json b/msigdb_wp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..5f6d95522f9ff47908d57ef849a37552c0d5aad1 --- /dev/null +++ b/msigdb_wp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["15q112 copy number variation syndrome", "15q133 copy number variation syndrome", "16p112 distal deletion syndrome", "16p112 proximal deletion syndrome", "1q211 copy number variation syndrome", "22q112 copy number variation syndrome", "3q29 copy number variation syndrome", "4hydroxytamoxifen dexamethasone and retinoic acids regulation of p27 expression", "7oxoc and 7betahc pathways", "7q1123 copy number variation syndrome", "Acetylcholine synthesis", "Acquired partial lipodystrophy barraquersimons syndrome", "Acute viral myocarditis", "Adipogenesis", "Aerobic glycolysis", "Aflatoxin b1 metabolism", "Agerage pathway", "Airway smooth muscle cell contraction", "Alanine and aspartate metabolism", "Allograft rejection", "Alpha 6 beta 4 signaling pathway", "Altered glycosylation of muc1 in tumor microenvironment", "Alternative pathway of fetal androgen synthesis", "Alzheimers disease", "Alzheimers disease and mirna effects", "Amino acid metabolism", "Amino acid metabolism pathway excerpt histidine catabolism extension", "Ampactivated protein kinase ampk signaling", "Amyotrophic lateral sclerosis als", "Androgen receptor signaling pathway", "Angiogenesis", "Angiopoietinlike protein 8 regulatory pathway", "Angiotensin ii receptor type 1 pathway", "Antiviral and antiinflammatory effects of nrf2 on sarscov2 pathway", "Apoptosis", "Apoptosis modulation and signaling", "Apoptosis modulation by hsp70", "Apoptosisrelated network due to altered notch3 in ovarian cancer", "Arachidonate epoxygenase epoxide hydrolase", "Arrhythmogenic right ventricular cardiomyopathy", "Aryl hydrocarbon receptor pathway wp2586", "Aryl hydrocarbon receptor pathway wp2873", "Atm signaling in development and disease", "Atm signaling pathway", "Atr signaling", "Autophagy", "Autosomal recessive osteopetrosis pathways", "B cell receptor signaling pathway", "Base excision repair", "Bdnftrkb signaling", "Benzene metabolism", "Benzoapyrene metabolism", "Bile acids synthesis and enterohepatic circulation", "Biogenic amine synthesis", "Biomarkers for pyrimidine metabolism disorders", "Biomarkers for urea cycle disorders", "Biotin metabolism including iems", "Bladder cancer", "Bmp signaling in eyelid development", "Bmp2wnt4foxo1 pathway in primary endometrial stromal cell differentiation", "Brainderived neurotrophic factor bdnf signaling pathway", "Breast cancer pathway", "Burn wound healing", "Calcium regulation in cardiac cells", "Caloric restriction and aging", "Camkk2 pathway", "Cancer immunotherapy by ctla4 blockade", "Cancer immunotherapy by pd1 blockade", "Cannabinoid receptor signaling", "Canonical and noncanonical notch signaling", "Canonical and noncanonical tgfb signaling", "Canonical nfkb pathway", "Cardiac hypertrophic response", "Cardiac progenitor differentiation", "Ccl18 signaling pathway", "Cell cycle", "Cell differentiation expanded index", "Cell migration and invasion through p75ntr", "Cells and molecules involved in local acute inflammatory response", "Cellular proteostasis", "Cerebral organic acidurias including diseases", "Chemokine signaling pathway", "Cholesterol biosynthesis pathway", "Cholesterol biosynthesis with skeletal dysplasias", "Cholesterol metabolism with bloch and kandutschrussell pathways", "Chromosomal and microsatellite instability in colorectal cancer", "Ciliary landscape", "Ciliopathies", "Circadian rhythm genes", "Classical pathway of steroidogenesis with glucocorticoid and mineralocorticoid metabolism", "Clear cell renal cell carcinoma pathways", "Codeine and morphine metabolism", "Cohesin complex cornelia de lange syndrome", "Common pathways underlying drug addiction", "Complement and coagulation cascades", "Complement system", "Complement system in neuronal development and plasticity", "Congenital generalized lipodystrophy cgl", "Constitutive androstane receptor pathway", "Control of immune tolerance by vasoactive intestinal peptide", "Copper homeostasis", "Cori cycle", "Corticotropinreleasing hormone signaling pathway", "Cysteine and methionine catabolism", "Cytoplasmic ribosomal proteins", "Cytosine methylation", "Cytosolic dnasensing pathway", "Ddx1 as a regulatory component of the drosha microprocessor", "Degradation pathway of sphingolipids including diseases", "Deregulation of rab and rab effector genes in bladder cancer", "Development of ureteric collection system", "Disorders of folate metabolism and transport", "Disruption of postsynaptic signaling by cnv", "Dna damage response", "Dna damage response only atm dependent", "Dna irdamage and cellular response via atr", "Dna irdouble strand breaks and cellular response via atm", "Dna mismatch repair", "Dna repair pathways full network", "Dna replication", "Dopamine metabolism", "Drug induction of bile acid pathway", "Dual hijack model of vif in hiv infection", "Ebola virus infection in host", "Ebsteinbarr virus lmp1 signaling", "Ectoderm differentiation", "Effect of progerin on genes involved in hutchinsongilford progeria syndrome", "Egfegfr signaling pathway", "Egfr tyrosine kinase inhibitor resistance", "Eicosanoid metabolism via cyclooxygenases cox", "Eicosanoid metabolism via lipooxygenases lox", "Eicosanoid synthesis", "Electron transport chain oxphos system in mitochondria", "Embryonic stem cell pluripotency pathways", "Endochondral ossification", "Endochondral ossification with skeletal dysplasias", "Endoderm differentiation", "Endometrial cancer", "Endoplasmic reticulum stress response in coronavirus infection", "Endothelin pathways", "Energy metabolism", "Envelope proteins and their potential roles in edmd physiopathology", "Epithelial to mesenchymal transition in colorectal cancer", "Epo receptor signaling", "Erbb signaling pathway", "Erk pathway in huntingtons disease", "Estrogen metabolism", "Estrogen receptor pathway", "Estrogen signaling pathway", "Ethanol effects on histone modifications", "Ethanol metabolism production of ros by cyp2e1", "Eukaryotic transcription initiation", "Exerciseinduced circadian regulation", "Exrna mechanism of action and biogenesis", "Extracellular vesiclemediated signaling in recipient cells", "Extracellular vesicles in the crosstalk of cardiac cells", "Factors and pathways affecting insulinlike growth factor igf1akt signaling", "Familial hyperlipidemia type 1", "Familial hyperlipidemia type 2", "Familial hyperlipidemia type 3", "Familial hyperlipidemia type 4", "Familial hyperlipidemia type 5", "Familial partial lipodystrophy fpld", "Farnesoid x receptor pathway", "Fas ligand pathway and stress induction of heat shock proteins", "Fatty acid betaoxidation", "Fatty acid biosynthesis", "Fatty acid omegaoxidation", "Fatty acid transporters", "Fbxl10 enhancement of maperk signaling in diffuse large bcell lymphoma", "Ferroptosis", "Fgf23 signaling in hypophosphatemic rickets and related disorders", "Fgfr3 signaling in chondrocyte proliferation and terminal differentiation", "Fibrin complement receptor 3 signaling pathway", "Fluoroacetic acid toxicity", "Fluoropyrimidine activity", "Focal adhesion", "Focal adhesion pi3kaktmtorsignaling pathway", "Folate metabolism", "Folatealcohol and cancer pathway hypotheses", "Follicle stimulating hormone fsh signaling pathway", "Foxa2 pathway", "Fragile x syndrome", "Fto obesity variant mechanism", "G protein signaling pathways", "G1 to s cell cycle control", "G13 signaling pathway", "Gaba metabolism aka ghb", "Gaba receptor signaling", "Galanin receptor pathway", "Gammaglutamyl cycle for the biosynthesis and degradation of glutathione including diseases", "Gastric cancer network 1", "Gastric cancer network 2", "Gastrin signaling pathway", "Gdnfret signaling axis", "Genes controlling nephrogenesis", "Genes related to primary cilium development based on crispr", "Genes targeted by mirnas in adipocytes", "Glial cell differentiation", "Glioblastoma signaling pathways", "Glucocorticoid receptor pathway", "Glucuronidation", "Glutathione metabolism", "Glycerolipids and glycerophospholipids", "Glycerophospholipid biosynthetic pathway", "Glycogen synthesis and degradation", "Glycolysis and gluconeogenesis", "Glycolysis in senescence", "Glycosaminoglycan degradation", "Glycosylation and related congenital defects", "Gpcrs class a rhodopsinlike", "Gpr143 in melanocytes and retinal pigment epithelium cells", "Gpr40 pathway", "H19 action rbe2f1 signaling and cdkbetacatenin activity", "Hair follicle development cytodifferentiation part 3 of 3", "Hair follicle development organogenesis part 2 of 3", "Head and neck squamous cell carcinoma", "Heart development", "Hedgehog signaling pathway wp4249", "Hedgehog signaling pathway wp47", "Hematopoietic stem cell gene regulation by gabp alphabeta complex", "Heme biosynthesis", "Hepatitis b infection", "Hepatitis c and hepatocellular carcinoma", "Hepatocyte growth factor receptor signaling", "Hereditary leiomyomatosis and renal cell carcinoma pathway", "Hif1a and pparg regulation of glycolysis", "Hijack of ubiquitination by sarscov2", "Hippo signaling regulation pathways", "Hippomerlin signaling dysregulation", "Hippoyap signaling pathway", "Histone modifications", "Homologous recombination", "Hostpathogen interaction of human coronaviruses apoptosis", "Hostpathogen interaction of human coronaviruses autophagy", "Hostpathogen interaction of human coronaviruses interferon induction", "Hostpathogen interaction of human coronaviruses mapk signaling", "Hypertrophy model", "Hypothesized pathways in pathogenesis of cardiovascular disease", "Hypothetical craniofacial development pathway", "Id signaling pathway", "Il1 signaling pathway", "Il10 antiinflammatory signaling pathway", "Il17 signaling pathway", "Il18 signaling pathway", "Il2 signaling pathway", "Il3 signaling pathway", "Il4 signaling pathway", "Il5 signaling pathway", "Il6 signaling pathway", "Il7 signaling pathway", "Il9 signaling pathway", "Imatinib and chronic myeloid leukemia", "Immune response to tuberculosis", "Inclusion body myositis", "Inflammatory response pathway", "Influence of laminopathies on wnt signaling", "Inhibition of exosome biogenesis and secretion by manumycin a in crpc cells", "Initiation of transcription and translation elongation at the hiv1 ltr", "Insulin signaling", "Insulin signaling in adipocytes diabetic condition", "Insulin signaling in adipocytes normal condition", "Integrated cancer pathway", "Integrinmediated cell adhesion", "Interactions between loxl4 and oxidative stress pathway", "Interactions of natural killer cells in pancreatic cancer", "Interactome of polycomb repressive complex 2 prc2", "Interferon type i signaling pathways", "Interleukin1 il1 structural pathway", "Interleukin1 induced activation of nfkb", "Interleukin11 signaling pathway", "Intracellular trafficking proteins involved in cmt neuropathy", "Intraflagellar transport proteins binding to dynein", "Irinotecan pathway", "Iron metabolism in placenta", "Joubert syndrome", "Kallmann syndrome", "Kennedy pathway from sphingolipids", "Ketogenesis and ketolysis", "Ketone bodies synthesis and degradation", "Kininkallikrein pathway", "Kisspeptinkisspeptin receptor system in the ovary", "Kit receptor signaling pathway", "Krebs cycle disorders", "Kynurenine pathway and links to cell senescence", "Ldlrad4 and what we know about it", "Leptin and adiponectin", "Leptin signaling pathway", "Leptininsulin signaling overlap", "Leukocyteintrinsic hippo pathway functions", "Linoleic acid metabolism affected by coronavirus infection", "Lipid metabolism pathway", "Lipid particles composition", "Liver x receptor pathway", "Lncrna in canonical wnt signaling and colorectal cancer", "Lncrnamediated mechanisms of therapeutic resistance", "Ltf danger signal response pathway", "Lung fibrosis", "Male infertility", "Malignant pleural mesothelioma", "Mammalian disorder of sexual development", "Mammary gland development pathway embryonic development stage 1 of 4", "Mammary gland development pathway involution stage 4 of 4", "Mammary gland development pathway pregnancy and lactation stage 3 of 4", "Mammary gland development pathway puberty stage 2 of 4", "Map3k1 role in promoting and blocking gonadal determination", "Mapk and nfkb signaling pathways inhibited by yersinia yopj", "Mapk cascade", "Mapk pathway in congenital thyroid cancer", "Mapk signaling pathway", "Matrix metalloproteinases", "Mbdnf and probdnf regulation of gaba neurotransmission", "Measles virus infection", "Mechanoregulation and pathology of yaptaz via hippo and nonhippo mechanisms", "Mecp2 and associated rett syndrome", "Melanoma", "Melatonin metabolism and effects", "Mesodermal commitment pathway", "Met in type 1 papillary renal cell carcinoma", "Metabolic pathway of ldl hdl and tg including diseases", "Metabolic reprogramming in colon cancer", "Metabolism of alphalinolenic acid", "Metabolism of spingolipids in er and golgi apparatus", "Metapathway biotransformation phase i and ii", "Metastatic brain tumor", "Methionine de novo and salvage pathway", "Methionine metabolism leading to sulfur amino acids and related disorders", "Methylation pathways", "Mevalonate arm of cholesterol biosynthesis pathway", "Mevalonate pathway", "Mfap5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement", "Mfap5mediated ovarian cancer cell motility and invasiveness", "Microglia pathogen phagocytosis pathway", "Microrna network associated with chronic lymphocytic leukemia", "Micrornas in cardiomyocyte hypertrophy", "Microtubule cytoskeleton regulation", "Mir124 predicted interactions with cell cycle and differentiation", "Mir517 relationship with arcn1 and usp1", "Mirna biogenesis", "Mirna regulation of dna damage response", "Mirna regulation of p53 pathway in prostate cancer", "Mirna regulation of prostate cancer signaling pathways", "Mirna targets in ecm and membrane receptors", "Mirnas involved in dna damage response", "Mirnas involvement in the immune response in sepsis", "Mitochondrial complex i assembly model oxphos system", "Mitochondrial complex ii assembly", "Mitochondrial complex iii assembly", "Mitochondrial complex iv assembly", "Mitochondrial fatty acid synthesis pathway", "Mitochondrial gene expression", "Mitochondrial immune response to sarscov2", "Mitochondrial long chain fatty acid betaoxidation", "Modulators of tcr signaling and t cell activation", "Molybdenum cofactor moco biosynthesis", "Monoamine transport", "Mrna processing", "Mrna protein and metabolite inducation pathway by cyclosporin a", "Mthfr deficiency", "Myd88 distinct inputoutput pathway", "Myometrial relaxation and contraction pathways", "Nad biosynthetic pathways", "Nad metabolism", "Nad metabolism in oncogeneinduced senescence and mitochondrial dysfunctionassociated senescence", "Nad metabolism sirtuins and aging", "Nanomaterial induced apoptosis", "Nanomaterialinduced inflammasome activation", "Nanoparticle triggered autophagic cell death", "Nanoparticle triggered regulated necrosis", "Nanoparticlemediated activation of receptor signaling", "Ncrnas involved in wnt signaling in hepatocellular carcinoma", "Neovascularisation processes", "Nephrogenesis", "Nephrotic syndrome", "Netrinunc5b signaling pathway", "Network map of sarscov2 signaling pathway", "Neural crest cell migration during development", "Neural crest cell migration in cancer", "Neural crest differentiation", "Neurodegeneration with brain iron accumulation nbia subtypes pathway", "Neuroinflammation", "Neuroinflammation and glutamatergic signaling", "Nicotine effect on dopaminergic neurons", "Nipbl role in dna damage cornelia de lange syndrome", "Nitric oxide metabolism in cystic fibrosis", "Nocgmppkg mediated neuroprotection", "Nodlike receptor nlr signaling pathway", "Nonalcoholic fatty liver disease", "Nongenomic actions of 125 dihydroxyvitamin d3", "Nonhomologous end joining", "Nonsmall cell lung cancer", "Notch signaling", "Notch signaling pathway", "Notch1 regulation of endothelial cell calcification", "Novel intracellular components of rigilike receptor rlr pathway", "Nrf2 pathway", "Nrf2are regulation", "Nrp1triggered signaling pathways in pancreatic cancer", "Nsp1 from sarscov2 inhibits translation initiation in the host cell", "Nuclear receptors", "Nuclear receptors in lipid metabolism and toxicity", "Nuclear receptors metapathway", "Nucleotide excision repair", "Nucleotide excision repair in xeroderma pigmentosum", "Nucleotide metabolism", "Nucleotidebinding oligomerization domain nod pathway", "Oligodendrocyte specification and differentiation leading to myelin components for cns", "Omega3 omega6 fatty acid synthesis", "Omega9 fatty acid synthesis", "Oncostatin m signaling pathway", "Onecarbon metabolism", "Onecarbon metabolism and related pathways", "Orexin receptor pathway", "Osteoblast differentiation and related diseases", "Osteoclast signaling", "Osteopontin signaling", "Osx and mirnas in tooth development", "Ovarian infertility", "Overlap between signal transduction pathways contributing to lmna laminopathies", "Overview of interferonsmediated signaling pathway", "Overview of nanoparticle effects", "Oxidation by cytochrome p450", "Oxidative damage response", "Oxidative phosphorylation", "Oxidative stress response", "Oxysterols derived from cholesterol", "P38 mapk signaling pathway", "P53 transcriptional gene network", "Pancreatic adenocarcinoma pathway", "Parkinsons disease pathway", "Parkinubiquitin proteasomal system pathway", "Pathogenesis of sarscov2 mediated by nsp9nsp10 complex", "Pathogenic escherichia coli infection", "Pathways affected in adenoid cystic carcinoma", "Pathways of nucleic acid metabolism and innate immune sensing", "Pdgf pathway", "Pdgfrbeta pathway", "Pentose phosphate metabolism", "Pentose phosphate pathway in senescent cells", "Peroxiredoxin 2 induced ovarian failure", "Phase i biotransformations non p450", "Phosphodiesterases in neuronal function", "Phosphoinositides metabolism", "Photodynamic therapyinduced ap1 survival signaling", "Photodynamic therapyinduced hif1 survival signaling", "Photodynamic therapyinduced nfe2l2 nrf2 survival signaling", "Photodynamic therapyinduced nfkb survival signaling", "Photodynamic therapyinduced unfolded protein response", "Physicochemical features and toxicityassociated pathways", "Physiological and pathological hypertrophy of the heart", "Pi3kakt signaling pathway", "Pi3kaktmtor signaling pathway and therapeutic opportunities", "Pi3kaktmtor vitd3 signaling", "Pilocytic astrocytoma", "Ppar signaling pathway", "Pparalpha pathway", "Praderwilli and angelman syndrome", "Pregnane x receptor pathway", "Preimplantation embryo", "Primary focal segmental glomerulosclerosis fsgs", "Prion disease pathway", "Progeriaassociated lipodystrophy", "Prolactin signaling pathway", "Prostaglandin and leukotriene metabolism in senescence", "Prostaglandin synthesis and regulation", "Proteasome degradation", "Proteoglycan biosynthesis", "Proximal tubule transport", "Ptf1a related regulatory pathway", "Purine metabolism", "Purine metabolism and related disorders", "Purinergic signaling", "Pyrimidine metabolism", "Pyrimidine metabolism and related diseases", "Quercetin and nfkb ap1 induced apoptosis", "Rac1pak1p38mmp2 pathway", "Rala downstream regulated genes", "Ranklrank signaling pathway", "Ras and bradykinin pathways in covid19", "Ras signaling", "Regucalcin in proximal tubule epithelial kidney cells", "Regulation of actin cytoskeleton", "Regulation of apoptosis by parathyroid hormonerelated protein", "Regulation of sister chromatid separation at the metaphaseanaphase transition", "Regulation of wnt bcatenin signaling by small molecule compounds", "Regulatory circuits of the stat3 signaling pathway", "Relationship between inflammation cox2 and egfr", "Reninangiotensinaldosterone system raas", "Resistin as a regulator of inflammation", "Retinoblastoma gene in cancer", "Rett syndrome causing genes", "Riboflavin and coq disorders", "Robo4 and vegf signaling pathways crosstalk", "S1p receptor signal transduction", "Sars coronavirus and innate immunity", "Sarscov2 altering angiogenesis via nrp1", "Sarscov2 and covid19 pathway", "Sarscov2 b117 variant antagonises innate immune activation", "Sarscov2 innate immunity evasion and cellspecific immune response", "Sarscov2 replication organelle formation", "Selenium micronutrient network", "Serine metabolism", "Serotonin and anxiety", "Serotonin and anxietyrelated events", "Serotonin htr1 group and fos pathway", "Serotonin receptor 2 and elksrfgata4 signaling", "Serotonin receptor 467 and nr3c signaling", "Serotonin transporter activity", "Signal transduction through il1r", "Sleep regulation", "Small cell lung cancer", "Smc1smc3 role in dna damage cornelia de lange syndrome", "Somatroph axis gh and its relationship to dietary restriction and aging", "Sphingolipid metabolism in senescence", "Sphingolipid metabolism integrated pathway", "Sphingolipid metabolism overview", "Sphingolipid pathway", "Spinal cord injury", "Splicing factor nova regulated synaptic proteins", "Srebf and mir33 in cholesterol and lipid homeostasis", "Statin inhibition of cholesterol production", "Steroid biosynthesis", "Sterol regulatory elementbinding proteins srebp signaling", "Sting pathway in kawasakilike disease and covid19", "Striated muscle contraction pathway", "Sudden infant death syndrome sids susceptibility pathways", "Sulfation biotransformation reaction", "Supression of hmgb1 mediated inflammation by thbd", "Synaptic signaling pathways associated with autism spectrum disorder", "Synaptic vesicle pathway", "T cell receptor and costimulatory signaling", "Target of rapamycin tor signaling", "Tca cycle aka krebs or citric acid cycle", "Tca cycle and deficiency of pyruvate dehydrogenase complex pdhc", "Tca cycle in senescence", "Tca cycle nutrient use and invasiveness of ovarian cancer", "Tcell activation sarscov2", "Tcell antigen receptor tcr pathway during staphylococcus aureus infection", "Tcell receptor tcr signaling pathway", "Tgfbeta receptor signaling", "Tgfbeta receptor signaling in skeletal dysplasias", "Tgfbeta signaling in thyroid cells for epithelialmesenchymal transition", "Tgfbeta signaling pathway", "Thermogenesis", "Thiamine metabolic pathways", "Thymic stromal lymphopoietin tslp signaling pathway", "Thyroid hormones production and peripheral downstream signaling effects", "Thyroid stimulating hormone tsh signaling pathway", "Tlr4 signaling and tolerance", "Tnfalpha signaling pathway", "Tnfrelated weak inducer of apoptosis tweak signaling pathway", "Tolllike receptor signaling pathway", "Tolllike receptor signaling related to myd88", "Tp53 network", "Transcription cofactors ski and skil protein partners", "Transcription factor regulation in adipogenesis", "Transcription factors regulate mirnas related to cardiac hypertrophy", "Transcriptional activation by nrf2 in response to phytochemicals", "Translation factors", "Translation inhibitors in chronically activated pdgfra cells", "Transsulfuration and onecarbon metabolism", "Transsulfuration pathway", "Triacylglyceride synthesis", "Tryptophan catabolism leading to nad production", "Tryptophan metabolism", "Tumor suppressor activity of smarcb1", "Type 2 papillary renal cell carcinoma", "Type i collagen synthesis in the context of osteogenesis imperfecta", "Type i interferon induction and signaling during sarscov2 infection", "Type ii diabetes mellitus", "Type ii interferon signaling ifng", "Type iii interferon signaling", "Tyrobp causal network in microglia", "Ultraconserved region 339 modulation of tumor suppressor micrornas in cancer", "Unfolded protein response", "Urea cycle and associated pathways", "Urea cycle and metabolism of amino groups", "Urea cycle and related diseases", "Valproic acid pathway", "Vasopressinregulated water reabsorption", "Vegfavegfr2 signaling pathway", "Vitamin a and carotenoid metabolism", "Vitamin b12 disorders", "Vitamin b12 metabolism", "Vitamin b6dependent and responsive disorders", "Vitamin d in inflammatory diseases", "Vitamin d metabolism", "Vitamin d receptor pathway", "Vitamin dsensitive calcium signaling in depression", "White fat cell differentiation", "Wnt signaling", "Wnt signaling in kidney disease", "Wnt signaling pathway", "Wnt signaling pathway and pluripotency", "Wntbetacatenin signaling pathway in leukemia", "Zinc homeostasis"], "available_proteins": ["AAR2", "AARS", "AASS", "ABAT", "ABCB1", "ABCC1", "ABCD3", "ABCF1", "ABCF2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR2", "ACTR3", "ADA", "ADAM17", "ADAM9", "ADAR", "ADH5", "ADI1", "ADK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGL", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP8", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT1S1", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG2", "AMOT", "ANAPC1", "ANAPC2", "ANAPC5", "ANAPC7", "ANK3", "ANLN", "ANXA1", "ANXA2", "ANXA6", "AP1G1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "APBB1", "APC", "APEX1", "APLP2", "APMAP", "APP", "APRT", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP2", "ARG2", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARL2", "ARL3", "ARL8B", "ARMC8", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARVCF", "ASAH1", "ASCC3", "ASNA1", "ASNS", "ATAD2", "ATG9A", "ATIC", "ATP11C", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0D1", "ATP6V1A", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPAF2", "ATPIF1", "ATRX", "ATXN10", "ATXN2L", "AURKB", "BAG4", "BAIAP2", "BANF1", "BAX", "BAZ1A", "BAZ1B", "BCAS3", "BCAT2", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BLM", "BLVRA", "BPTF", "BRCA1", "BRD4", "BRIX1", "BSG", "BTF3", "BTRC", "BUB1B", "BUB3", "BUD23", "C1QBP", "CAB39", "CACYBP", "CAD", "CADM1", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CANT1", "CAP1", "CAPN1", "CAPN2", "CAPN7", "CAPNS1", "CAPZB", "CARM1", "CASK", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CCAR2", "CCDC124", "CCDC6", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD47", "CDC20", "CDC23", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC45", "CDC6", "CDC73", "CDCA5", "CDCA7L", "CDH2", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CDKAL1", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPB", "CEP170", "CEP250", "CERS1", "CERS2", "CETN2", "CFL1", "CFL2", "CHAF1A", "CHAMP1", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD8", "CHEK2", "CHKA", "CHMP5", "CHMP6", "CHORDC1", "CHP1", "CHRAC1", "CHST14", "CHTF18", "CHUK", "CIP2A", "CISD1", "CKB", "CLASP1", "CLASP2", "CLCN7", "CLIC1", "CLPTM1L", "CLTA", "CLTC", "CLU", "CLUH", "CMPK1", "CNN2", "CNOT1", "CNOT10", "CNOT9", "CNP", "COA3", "COLEC12", "COLGALT1", "COMT", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COQ8A", "COQ8B", "COQ9", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPT1A", "CPT2", "CREB1", "CRKL", "CRTAP", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTH", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYB5B", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAGLB", "DARS", "DAXX", "DBNL", "DCAF1", "DCAF7", "DCP1A", "DCTN1", "DCTN2", "DCTN4", "DCTPP1", "DDB1", "DDOST", "DDX1", "DDX17", "DDX20", "DDX21", "DDX3X", "DDX5", "DDX52", "DDX56", "DECR1", "DEK", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX36", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DLAT", "DLD", "DLG1", "DLST", "DNAAF5", "DNAJA1", "DNAJB1", "DNAJB4", "DNAJC3", "DNAJC7", "DNAJC8", "DNM1L", "DNM2", "DNMT1", "DPF2", "DPM1", "DPYSL2", "DSC2", "DSC3", "DSG2", "DSP", "DSTN", "DTYMK", "DUSP3", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EBP", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECSIT", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFTUD2", "EGFR", "EHD1", "EHHADH", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF4A1", "EIF4A2", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAVL1", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP3", "EMD", "EML4", "ENAH", "ENO1", "ENO2", "ENPP1", "EPB41", "EPB41L2", "EPB41L3", "EPHX1", "EPN1", "EPRS", "EPS15", "EPS15L1", "ERBIN", "ERCC2", "ERCC3", "ESD", "ESPL1", "ESS2", "ETF1", "ETFA", "ETFDH", "ETNK1", "EWSR1", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOSC2", "EXOSC4", "EXOSC7", "EXOSC9", "EZH2", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAH", "FAM120A", "FANCD2", "FANCI", "FARSB", "FASN", "FAU", "FDFT1", "FDPS", "FECH", "FEN1", "FGFR1OP", "FH", "FHL1", "FHOD1", "FKBP10", "FKBP15", "FKBP1A", "FKBP2", "FKBP4", "FKBP5", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FOXRED1", "FSCN1", "FTO", "FUCA1", "FUS", "FXR1", "FXR2", "G3BP1", "G6PD", "GABARAPL2", "GALNT1", "GAPDH", "GART", "GBA", "GCC2", "GCDH", "GDAP1", "GDI1", "GFPT1", "GGCT", "GGCX", "GGH", "GGPS1", "GIGYF2", "GLA", "GLB1", "GLS", "GLUD1", "GM2A", "GMPPB", "GNA13", "GNAI2", "GNAI3", "GNB1L", "GNG12", "GNG5", "GNPAT", "GNS", "GOT1", "GOT2", "GPAM", "GPAT4", "GPD2", "GPHN", "GPI", "GPS1", "GRB2", "GRSF1", "GSK3B", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F2", "GTF2I", "GTPBP4", "GUSB", "GYG1", "GYS1", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HADH", "HADHA", "HADHB", "HAT1", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HEBP1", "HELLS", "HERC2", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HIRA", "HIRIP3", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGCL", "HMGCS1", "HMGN1", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HPRT1", "HPSE", "HS2ST1", "HSD17B10", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HTRA2", "HTT", "HYOU1", "IARS", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP3", "ILF2", "ILK", "IMP3", "IMPAD1", "IMPDH2", "INF2", "IPO9", "IQGAP1", "IQGAP2", "IRF2BPL", "IRS4", "ITCH", "ITGB1", "ITM2C", "ITPA", "IVD", "JUP", "KAT7", "KDM1A", "KDM1B", "KDM3B", "KDM5A", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIF1B", "KIF20B", "KIF22", "KIF23", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KLC1", "KLC2", "KLC4", "KMT2A", "KPNA1", "KPNA4", "KPNB1", "KTN1", "L2HGDH", "LAMB1", "LAMC1", "LAMTOR3", "LARP1", "LARP7", "LARS2", "LBR", "LDHA", "LDHB", "LDLR", "LEMD3", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIPA", "LLGL1", "LMAN1", "LMNA", "LMNB1", "LMNB2", "LONP2", "LPGAT1", "LRP1", "LRP2", "LRPPRC", "LRRC59", "LRRC8C", "LRRFIP2", "LRSAM1", "LRWD1", "LSM2", "LSM7", "LSS", "LTA4H", "LUC7L", "LUZP1", "LYN", "LZTFL1", "MACF1", "MAD2L1", "MAGED1", "MAGT1", "MANF", "MAP1B", "MAP2K1", "MAP2K4", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCKS", "MARK2", "MARK3", "MARS", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD1", "MBD3", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDC1", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED1", "MED14", "MEPCE", "MFAP1", "MGST1", "MGST2", "MGST3", "MIA3", "MIF", "MKI67", "MMAB", "MOGS", "MORF4L1", "MOV10", "MPC2", "MPG", "MPI", "MPP1", "MPP2", "MPP5", "MPST", "MRE11", "MRPL19", "MRPL40", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTDH", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTM1", "MTMR2", "MTMR6", "MTOR", "MTR", "MUT", "MYBBP1A", "MYCBP", "MYCBP2", "MYEF2", "MYH10", "MYH9", "MYL6", "MYO1C", "MYO1E", "MYO6", "NAA15", "NAA40", "NAA50", "NAE1", "NAGLU", "NAMPT", "NAP1L1", "NAPA", "NARS", "NAT10", "NBN", "NCAM1", "NCAPG", "NCBP1", "NCDN", "NCK1", "NCK2", "NCKAP1", "NCL", "NCSTN", "ND1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFC2", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NEU1", "NF2", "NFRKB", 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sha256:87e044093bd1974f50703cc2df559f9da3d990db22352623c58da3db3cb2512c +size 146451 diff --git a/opencell_localization/consensus.joblib b/opencell_localization/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..3b3edf3dcb52ea9d8b5c005332450dc225cb55c2 --- /dev/null +++ b/opencell_localization/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:83c99d4c32360823829cdec2273328def38dddc14ed8e1298c3045decc61df18 +size 76557 diff --git a/opencell_localization/df_merge.tsv b/opencell_localization/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..4499fe3467c43fb5f9be0e65b9c7919c757b0cbc --- /dev/null +++ b/opencell_localization/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +er 27 91 2.487283582877438 0.0128722745343559 29.17233009708738 87.61893203883496 1.3358083950399515 0.3757472714196316 13.465054065187209 8.223393744963309 2.0429537263872786 0.4010648005920765 0.0079487644383872 0.148662677751522 0.011785471900189 0.0024194651079028 5.711544376186879e-05 +mitochondria 5 10 2.059836123934913 0.0394142098758407 4.441747572815534 10.567961165048544 1.1937677940164793 0.2159787381789819 2.254231157409949 0.7391563798220593 1.4011905974754153 0.2980089661914649 1.0 1.0 1.0 0.2740704871267072 0.0028040242445346 diff --git a/opencell_localization/metrics.json b/opencell_localization/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..2829c2f617982e626d2b17effc505b7fe1f09e10 --- /dev/null +++ b/opencell_localization/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3381, + "annotations_size": 17, + "title": "Average number of proteins per term", + "value": 100.0 +} \ No newline at end of file diff --git a/opencell_localization/paths.json b/opencell_localization/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..e55da8adf553476ad6b5019e223c492b8293382f --- /dev/null +++ b/opencell_localization/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/opencell_localization/fragment/C317/C317_val_log2fc"} \ No newline at end of file diff --git a/opencell_localization/result.tsv b/opencell_localization/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..908948e764de2266c489b600ed5a020f742066df --- /dev/null +++ b/opencell_localization/result.tsv @@ -0,0 +1,7 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +er 0.4128172008672039 2.487283582877438 0.0128722745343559 0.1976812310984841 0.1094143335420252 91 P48449,Q9NQC3,Q8TBX8,Q96A33,Q969V3,Q13190,Q12981,O95470,Q07065,Q16850,Q8NHH9,Q9NR31,Q15125,P04843,O15173,O96005,Q15392,Q15363,O00264,Q14739,Q9Y5M8,Q9Y487,Q9P2W9,P49755,Q06136,Q8WUX9,Q969Q5 27 +mitochondria 0.6994417379535579 2.059836123934913 0.0394142098758407 0.4952054194655443 0.223347189296431 10 Q9NR31,Q8IWA4,P21796,Q969Q5,P45880 5 +centrosome 0.3728523133144985 0.6482333483353173 0.5168340357922669 0.999995737762256 1.0 40 Q13561,Q9H0B6,P33176,Q9BV73,O60333,Q66GS9,P25054,P0DP25,P06493,Q10713,P41208 11 +vesicles 0.3305280105745923 0.5491571277547623 0.5828976232444321 0.9999996499538562 1.0 183 O43633,P48449,P31751,Q2M1P5,Q969V3,P17812,O43808,Q8IXU6,P49257,P30825,P50570,Q10713,O95470,O95249,Q9Y5X3,P05023,P31749,Q15125,O43752,O15173,O00429,O60476,Q13277,Q93050,O96005,Q15392,Q15363,Q5VW38,O00264,Q9Y3P9,Q13501,Q8IY95,O75845,Q15075,O60826,Q15437,Q15276,P49755,O14964,Q06136,Q8WUX9,O15027,Q567U6,Q9Y5K8,Q96QK1,O15144 46 +golgi 0.336188128974773 0.4488158269358726 0.653564520551889 0.9999999850864796 1.0 60 P53365,Q9NR31,Q9Y487,Q08379,Q8IXU6,Q5VW38,Q9Y3P9,Q15437,P49755 9 +cytoskeleton 0.3108048882585344 0.1702168879749891 0.864839570844121 0.9999999999999984 1.0 37 Q13561,P35580,P08670,P06493,Q96DE5,P35579,O43707,P12814,P60660 9 diff --git a/opencell_localization/selections.json b/opencell_localization/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..188d9d27845aa71c87fdcb7aa90712748f9f89e7 --- /dev/null +++ b/opencell_localization/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["big_aggregates", "cell_contact", "centrosome", "chromatin", "cytoplasmic", "cytoskeleton", "er", "focal_adhesions", "golgi", "membrane", "mitochondria", "nuclear_membrane", "nuclear_punctae", "nucleolus_fc_dfc", "nucleolus_gc", "nucleoplasm", "vesicles"], "available_proteins": ["AATF", "ABCE1", "ACLY", "ACTN1", "ACTN4", "ACTR2", "AHCY", "AHSA1", "AKAP12", "AKAP13", "AKAP8L", "AKR1A1", "AKT1", "AKT1S1", "AKT2", "ALCAM", "ALDH9A1", "ALG2", "ANAPC16", "ANAPC2", "ANKRD17", "ANXA11", "AP2B1", "AP2S1", "APC", "APLP2", "ARF4", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARHGAP17", "ARID1A", "ARL1", "ARL2", "ARL3", "ARL6IP1", 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"COPE", "COPG1", "COPG2", "COPZ1", "CORO1B", "CORO1C", "CPSF6", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CTBP1", "CTBP2", "CTCF", "CTNNB1", "CTNNBL1", "CTPS1", "CTTN", "CYB5R3", "CYP51A1", "DAD1", "DBNL", "DCP1A", "DCP2", "DCTN2", "DDB1", "DDOST", "DDX21", "DDX39B", "DDX47", "DDX5", "DDX56", "DDX6", "DHCR24", "DHX37", "DHX9", "DIAPH1", "DKC1", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB4", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DOCK7", "DPH2", "DRG1", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "DYNLL2", "EBNA1BP2", "EBP", "EDC3", "EDC4", "EDF1", "EEA1", "EEF1G", "EFTUD2", "EIF2AK2", "EIF3B", "EIF3E", "EIF3G", "EIF3I", "EIF3K", "EIF3M", "EIF4A1", "EIF4A3", "EIF5", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMG1", "ENO1", "EPN1", "EPS15", "ESD", "ESYT1", "EWSR1", "EZR", "FAM120A", "FASN", "FAU", "FBL", "FDPS", "FKBP5", "FKBP8", "FNBP1L", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAK", "GAPDH", "GAR1", "GBF1", "GDI1", "GDI2", "GET4", 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"POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR3A", "POLR3C", "POLR3F", "PPM1G", "PRKAA1", "PRKACA", "PRKCD", "PRKDC", "PRMT9", "PRPF19", "PRPF4B", "PRPF8", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTDSS1", "PTDSS2", "PTGES3", "PTK7", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB23", "RAB24", "RAB2A", "RAB35", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB7A", "RAB8B", "RAB9A", "RABEP1", "RABGAP1", "RABGGTA", "RAC1", "RACK1", "RAD21", "RAN", "RANBP1", "RANBP2", "RANBP9", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM5", "RBM6", "RBM8A", "RBMX", "REEP3", "REEP4", "REEP5", "RER1", "RHEB", "RHOA", "RHOG", "RICTOR", "RNASEH2A", "RNF40", "ROCK1", "RPL10A", "RPL11", "RPL13", "RPL19", "RPL27", "RPL35", "RPL4", "RPL5", "RPN1", "RPN2", "RPP30", "RPS11", "RPS14", "RPS16", "RPS18", "RPS6KA1", "RPS6KA3", "RRP1", "RSL1D1", "RTCB", "RTN4", "RUVBL1", "RUVBL2", "S100A10", "SACM1L", "SAE1", "SAR1A", "SAR1B", "SARS", "SBDS", "SC5D", "SCAMP1", "SCAMP2", "SCD", "SCFD1", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC24C", "SEC31A", "SEC61B", "SEPT11", "SEPT2", "SEPT7", "SEPT8", "SEPT9", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SGPL1", "SH3GL1", "SH3GLB1", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A17", "SLC27A4", "SLC35F2", "SLC5A6", "SLC6A15", "SLC7A1", "SLK", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMN1*", "SNRNP40", "SNRPA", "SNRPB2", "SNRPC", "SNRPD2", "SNU13", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX9", "SPNS1", "SPOUT1", 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"YES1", "YKT6", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZNF326", "ZNF598", "ZYX"], "leading_proteins": ["ACTN1", "ACTN4", "AKT1", "AKT2", "ANAPC16", "APC", "ARFIP2", "ARPC2", "ATL2", "ATP1A1", "ATP6V0A1", "ATP6V0A2", "ATP6V1D", "BNIP1", "CALM3", "CCDC22", "CCDC47", "CCDC93", "CDK1", "CEP135", "CEP250", "CETN2", "CHMP2A", "CHMP7", "CKAP4", "CLPTM1", "CTPS1", "CYP51A1", "DCTN2", "DHCR24", "DNM1L", "DNM2", "EBP", "EEA1", "GOLGA2", "GOSR1", "GPR107", "HGS", "KDSR", "KIF1B", "KIF5B", "KIF7", "KLC2", "LBR", "LMAN1", "LSS", "MAN1A2", "MFN1", "MYH10", "MYH9", "MYL6", "NCLN", "PGRMC1", "PGRMC2", "PIP4K2C", "PMPCA", "RAB24", "RABEP1", "RABGAP1", "RPN1", "RTN4", "SAR1A", "SC5D", "SEC16A", "SEC23B", "SGPL1", "SLC25A17", "SLC35F2", "SLC7A1", "SNX5", "SQSTM1", "SRPRB", "STX18", "STX3", "STX5", "STX6", "TMED10", "TMED2", "TMEM192", "VDAC1", "VDAC2", "VIM", "VPS35"]} \ No newline at end of file diff --git a/panther_protein_class/advanced/idx2term.json 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0.2930923238696635 0.0340600731539348 0.2443632781182481 0.107004894081217 0.0004830692131202 1.8042165381148847e-05 +primary active transporter 10 25 2.931300006539519 0.0033754662966491 8.614077669902912 23.45631067961165 1.2392440710771837 0.271771563990288 4.792195908457348 3.1431129799052804 1.4794913205770832 0.3014776193450941 0.0069435670104348 0.0356328568827733 0.0216384292134882 0.0038382700604267 0.0304236608893936 +calmodulin-related 6 15 2.405163051908436 0.0161652514588184 5.053398058252427 12.385922330097088 1.3935892727836532 0.1814075830019033 2.0222219603900085 1.786979844553702 1.206053991839631 0.2252292235861566 0.003397299736501 0.1135912525516411 0.0237627189197599 2.340849497796301e-05 0.0001398373652982 +ATP synthase 12 21 2.246231801401445 0.0246891642687814 6.381067961165049 20.483009708737864 0.8573640874951715 0.3249378356888472 2.8850015270213047 1.3977105655851854 1.2517106680730556 0.3017789026221172 0.0005242473055266 0.0004265388560116 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a/panther_protein_class/metrics.json b/panther_protein_class/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..f06c7ae5b5fbb660a1f5deeadcab10e460a8c764 --- /dev/null +++ b/panther_protein_class/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3381, + "annotations_size": 163, + "title": "Average number of proteins per term", + "value": 14.012269938650308 +} \ No newline at end of file diff --git a/panther_protein_class/paths.json b/panther_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..77d1c13487361a760313f162b8ca43c3495fa42e --- /dev/null +++ b/panther_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/panther_protein_class/fragment/C317/C317_val_log2fc"} \ No newline at end of file diff --git a/panther_protein_class/result.tsv b/panther_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..a27cc7c8887db36e8719f9be060d5706ac66d9d1 --- /dev/null +++ b/panther_protein_class/result.tsv @@ -0,0 +1,48 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +protein modifying enzyme 0.6672372361663892 2.933529314105313 0.0033513200570325 0.4214223843380548 0.2751005031769097 29 Q92791,O60476,Q6P2P2,O60678,O75718,O60725,P33908,Q86X55,Q86YN1,Q6PK18,Q15418 11 +primary active transporter 0.6701394049046372 2.931300006539519 0.0033754662966491 0.4237027507984601 0.2751005031769097 25 O60888,O75381,Q8N4H5,P05023,Q9Y5J7,P12270,Q9NS69,P16615,Q6P4A7,P98194 10 +calmodulin-related 0.67934602042218 2.405163051908436 0.0161652514588184 0.9298041105654772 0.509748736998498 15 P0DP25,Q8IYU8,P80303,O43852,Q14257,Q9BPX6 6 +ATP synthase 0.5729947079456397 2.2462318014014455 0.0246891642687814 0.9830051619468558 0.509748736998498 21 P00846,Q9UI12,O75964,Q9Y487,Q9Y5K8,Q93050,P06576,Q15904,P24539,Q96IX5,Q6IN85,P21281 12 +oxygenase 0.7930194564483982 2.2006459112580026 0.0277611006970841 0.989837562333979 0.509748736998498 7 Q16850,P30519,P09601 3 +transmembrane signal receptor 0.7856096174531599 2.167294635527094 0.03021239528796 0.9932657302091736 0.509748736998498 7 Q9UMX5,Q99720,Q8WUJ1 3 +transporter 0.496449027868387 1.9963153870648265 0.0458996042289787 0.9995281169391044 0.509748736998498 58 O60830,Q99805,Q96P70,Q8N8Q8,O43681,Q99595,O43772,O00410,Q9NR77,Q9C0E2,Q99567,Q8N1F7,Q9H2D1,Q9HD45,Q92973,Q567V2,P54105,Q92544,Q8TEX9 19 +serine protease 0.5771536653542444 1.9450594480559835 0.0517678238116012 0.9998273787905684 0.509748736998498 17 P67812,Q4J6C6,Q9H3G5,P13798,P42785 5 +oxidase 0.5593404120253697 1.827369806793542 0.0676441858604082 0.9999889893135264 0.5398848375755656 17 O75880,Q6ZRP7,Q15800,P13073,P14406 5 +amino acid transporter 0.7722739010391654 1.8147088918663077 0.0695686578606988 0.9999921377649328 0.5398848375755656 5 O14925,P30825 2 +SNARE protein 0.6078661951625577 1.8016706126600537 0.0715972443053003 0.9999944914588164 0.5398848375755656 12 O95249,O43752,O95721,Q13277,Q9P2W9 5 +mitochondrial carrier protein 0.694934374461958 1.6726893952421835 0.094388457983956 0.9999999041620136 0.5398848375755656 6 Q70HW3 1 +voltage-gated ion channel 0.8793568974967896 1.664296804904495 0.0960531306116037 0.99999992899425 0.5398848375755656 3 P21796 1 +esterase 0.6487453164342447 1.6091057731988647 0.1075932151002794 0.999999991255263 0.5480529394170482 8 Q9NUJ1,Q969T7 2 +G-protein coupled receptor 0.838069863824733 1.502793142339253 0.1328923948760267 0.9999999999194812 0.6083463905754665 3 Q9NPR9,Q5VW38 2 +transcription cofactor 0.5681958039708006 1.4634111388341755 0.1433549125679354 0.9999999999888686 0.6083463905754665 11 Q99417,O00625,P51858 3 +glycosyltransferase 0.447480198497916 1.2923863083225997 0.1962233958610437 0.9999999999999996 0.6562636627229207 23 P04843,Q68CQ7,Q10472,Q9BT22,Q9Y2G5,P46977,P46976,Q10471,Q16739 9 +extracellular matrix glycoprotein 0.9112163361941404 1.25767175703538 0.2085104904246089 1.0 0.6562636627229207 2 Q8IVL6 1 +actin binding motor protein 0.5774056278245198 1.253050034830726 0.2101874981300762 1.0 0.6562636627229207 8 P67936,P09493 2 +decarboxylase 0.6853083293217287 1.238693509677365 0.2154590231927462 1.0 0.6562636627229207 4 Q8NBZ7,P14174 2 +acyltransferase 0.490714726517326 1.2366269483091017 0.2162256105424567 1.0 0.6562636627229207 15 Q9BWD1 1 +histone modifying enzyme 0.4974609877585292 1.2302163915798756 0.218616083299016 1.0 0.6562636627229207 14 Q9H0E3,Q15047,Q8WTS6,Q03164 4 +oxidoreductase 0.428520203058112 1.1854408336591191 0.2358431949041897 1.0 0.6562636627229207 48 Q15067,Q8N0U8,P00403,O95831,O43169,O14949,O15254,O96000,O43676,Q86Y39,Q8N4Q0 11 +metalloprotease 0.436279440979143 1.183425610756613 0.2366405122511856 1.0 0.6562636627229207 28 Q6P179,Q9NZ08,P22695,Q5JRX3,P55786,O75844,P52888 7 +membrane traffic protein 0.3861204520064832 1.1342104784546994 0.2567062696836371 1.0 0.6562636627229207 68 O43633,P40855,Q9Y2T2,O60313,Q96ED9,Q96D71,P49257,P50570,Q9NX40,P43307,Q9HD26,Q5JRA6,Q9H3S7,O00429,Q08379,A6NIH7,Q9H223,Q8TAG9,Q96A65,Q8IUD2,O60763,Q8WUX9,Q96QK1,Q9BRG1,Q96PC5 25 +kinase 0.425041009188035 1.1223815784358568 0.2617002336011647 1.0 0.6562636627229207 22 P52789,Q8TBX8,Q13232,Q9BRR6,Q9HBU6,P35790 6 +secondary carrier transporter 0.4700230793063141 1.0576399018218208 0.2902196438216498 1.0 0.6956735579842488 14 P55011,Q8TB61,O95202,Q9Y6M7,Q9UBX3 5 +microtubule binding motor protein 0.3869274399502055 0.8101531985591697 0.4178521322044193 1.0 0.8513737193665043 24 Q13561,Q9H0B6,P33176,O60333,O75935,Q8NCM8,Q15058 7 +guanyl-nucleotide exchange factor 0.4626033831347178 0.6810854135157124 0.4958174461675646 1.0 0.9106270144821024 8 Q14C86 1 +protease 0.3746574414877571 0.6623314935327165 0.5077587974927491 1.0 0.9196075999035344 38 P28072,P28070,P28074,P20618,P49721,Q9BT78 6 +membrane trafficking regulatory protein 0.3500082472951711 0.5623940720831586 0.573847557013804 1.0 0.9697931861041366 20 O43760,O43731,Q13439,Q15075,Q8WTV0,P24390 6 +ion channel 0.4305277300556122 0.4948292665636196 0.6207206436634725 1.0 0.9926500532200704 7 Q9C0H2 1 +replication origin binding protein 0.4384987955121752 0.3962417101953528 0.6919267238141658 1.0 1.0 5 O75419,Q13416 2 +translational protein 0.663213968629777 0.3864918695489473 0.6991324228957625 1.0 1.0 2 Q12904 1 +tight junction 0.627996448653453 0.2954051570845331 0.767684394215238 1.0 1.0 2 Q9UDY2 1 +chaperone 0.2955907088360602 0.2537831891218258 0.7996630614943667 1.0 1.0 73 O75937,P62942,P46379,P30533,Q9Y680,O00170,Q9NWM8,Q9NVA1,O95456,Q9UHV9,Q14203,Q96KC8,P07237,Q16543,Q9BRT2,O60884,Q9Y2R0,P78318,Q02790,O15260 20 +nucleic acid metabolism protein 0.3812203791469081 0.212362671361385 0.8318241055251878 1.0 1.0 5 Q9Y2W1,Q9UGR2,Q9NYF8,P49750 4 +chaperonin 0.3411938674592424 0.2050915577903966 0.83750059215089 1.0 1.0 10 P49368 1 +extracellular matrix protein 0.3578936363193108 0.2029254104772355 0.8391933327759311 1.0 1.0 6 P07942 1 +cytoskeletal protein 0.3503259334832374 0.1878377425294599 0.8510038480820117 1.0 1.0 7 Q15019,Q14141 2 +tubulin 0.3407407407407445 0.1526431394111993 0.8786797032852867 1.0 1.0 6 P68371,P07437,Q13509,Q13885,Q9BUF5 5 +vesicle coat protein 0.2921235608503377 0.1098575940063271 0.912522313996102 1.0 1.0 27 P53365,Q9Y3A6,Q9BVK6,Q92572,Q15363,Q15437,P49755 7 +viral or transposable element protein 0.3890032358115411 0.0847829830315669 0.9324339223971227 1.0 1.0 3 Q9H2J4 1 +mRNA capping factor 0.4406629180230922 0.044219976869461 0.9647290583884484 1.0 1.0 2 Q9NPI6 1 +primase 0.3986386504883196 0.0313844681849152 0.9749629276431696 1.0 1.0 2 P49643 1 +kinase activator 0.2934557299378103 0.0278219074849241 0.977804193078263 1.0 1.0 4 O95067,Q9Y3A3,P20248 3 +heterotrimeric G-protein 0.2680106121459689 0.0033467212983991 0.9973297077314855 1.0 1.0 6 Q8NHH9 1 diff --git a/panther_protein_class/selections.json b/panther_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..efffda63978be38330734748a1644e1f392cef93 --- /dev/null +++ b/panther_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthase", "ATP-binding cassette (ABC) transporter", "C2H2 zinc finger transcription factor", "C4 zinc finger nuclear receptor", "DNA glycosylase", "DNA helicase", "DNA ligase", "DNA metabolism protein", "DNA methyltransferase", "DNA polymerase processivity factor", "DNA topoisomerase", "DNA-binding transcription factor", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "G-protein", "G-protein coupled receptor", "G-protein modulator", "GTPase-activating protein", "Hsp90 family chaperone", "Lambda repressor-like transcription factor", "P53-like transcription factor", "RNA helicase", "RNA metabolism protein", "RNA methyltransferase", "RNA processing factor", "RNA splicing factor", "Rel homology transcription factor", "SNARE protein", "acetyltransferase", "actin and actin related protein", "actin binding motor protein", "actin or actin-binding cytoskeletal protein", "acyltransferase", "aldolase", "amino acid kinase", "amino acid transporter", "aminoacyl-tRNA synthetase", "antimicrobial response protein", "apolipoprotein", "aspartic protease", "basic helix-loop-helix transcription factor", "basic leucine zipper transcription factor", "cadherin", "calcium-binding protein", "calmodulin-related", "carbohydrate kinase", "cell adhesion molecule", "cell junction protein", "centromere DNA-binding protein", "chaperone", "chaperonin", "chromatin/chromatin-binding, or -regulatory protein", "cyclase", "cysteine protease", "cytokine", "cytoskeletal protein", "damaged DNA-binding protein", "deacetylase", "deaminase", "decarboxylase", "defense/immunity protein", "dehydratase", "dehydrogenase", "endodeoxyribonuclease", "endoribonuclease", "epimerase/racemase", "esterase", "exodeoxyribonuclease", "exoribonuclease", "extracellular matrix glycoprotein", "extracellular matrix protein", "extracellular matrix structural protein", "galactosidase", "general transcription factor", "glucosidase", "glycosidase", "glycosyltransferase", "growth factor", "guanyl-nucleotide exchange factor", "heterotrimeric G-protein", "histone", "histone modifying enzyme", "homeodomain transcription factor", "hydratase", "hydrolase", "hydroxylase", "immunoglobulin superfamily cell adhesion molecule", "integrin", "intercellular signal molecule", "intermediate filament binding protein", "ion channel", "isomerase", "kinase", "kinase activator", "kinase inhibitor", "kinase modulator", "ligase", "lipase", "lyase", "mRNA capping factor", "mRNA polyadenylation factor", "major histocompatibility complex protein", "membrane traffic protein", "membrane trafficking regulatory protein", "metalloprotease", "methyltransferase", "microtubule binding motor protein", "microtubule or microtubule-binding cytoskeletal protein", "mitochondrial carrier protein", "mutase", "non-motor actin binding protein", "non-motor microtubule binding protein", "non-receptor serine/threonine protein kinase", "nucleic acid metabolism protein", "nucleotide kinase", "nucleotide phosphatase", "nucleotidyltransferase", "oxidase", "oxidoreductase", "oxygenase", "peptide hormone", "peroxidase", "phosphatase", "phosphatase activator", "phosphatase modulator", "phosphodiesterase", "phospholipase", "primary active transporter", "primase", "protease", "protease inhibitor", "protein modifying enzyme", "protein phosphatase", "protein-binding activity modulator", "pyrophosphatase", "reductase", "replication origin binding protein", "ribosomal protein", "scaffold/adaptor protein", "secondary carrier transporter", "serine protease", "small GTPase", "structural protein", "tight junction", "transaminase", "transcription cofactor", "transfer/carrier protein", "transferase", "transketolase", "translation elongation factor", "translation factor", "translation initiation factor", "translation release factor", "translational protein", "transmembrane signal receptor", "transporter", "tubulin", "tyrosine protein kinase receptor", "ubiquitin-protein ligase", "vesicle coat protein", "viral or transposable element protein", "voltage-gated ion channel", "zinc finger transcription factor"], "available_proteins": ["AACS", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCF1", "ABCF2", "ABHD10", "ABHD12", "ABHD6", "ACAA1", "ACAA2", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ADA", "ADAM17", "ADAM9", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG2", "ALG5", "ALKBH5", "ALYREF", "AMPD2", "ANAPC1", "ANAPC7", "ANKFY1", "ANKHD1", "ANKRD17", "ANLN", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APLP2", "APOBEC3C", "APOL2", "APP", "APRT", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARG2", "ARHGDIA", "ARHGEF1", "ARIH1", "ARL1", "ARL6IP5", "ARPC1A", "ARPC3", "ARPC4", "ARVCF", "ASAH1", "ASCC3", "ASNA1", "ASNS", "ASPH", "ATAD2", "ATAD5", "ATG4B", "ATL2", "ATP11C", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "ATPAF1", "ATPAF2", "ATPIF1", "ATRX", "ATXN2L", "AUP1", "AURKB", "B4GAT1", "BAG6", "BAIAP2", "BAP18", "BAZ2A", "BCAP31", "BCAS2", "BCAT2", "BCLAF1", "BDH2", "BLM", "BLMH", "BLVRA", "BOP1", "BPNT1", "BRCA1", "BRD7", "BRIX1", "BSG", "BTF3", "BTRC", "BUB1B", "BUB3", "BUD23", "BUD31", "BZW1", "BZW2", "C1D", "CACYBP", "CAD", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CAST", "CBL", "CBR1", "CBX8", "CCAR1", "CCAR2", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2BP2", "CD3EAP", "CD47", "CDC20", "CDC23", "CDC27", "CDC37", "CDC40", "CDC42", "CDC45", "CDC6", "CDH2", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CDKN2AIP", "CDS2", "CEBPZ", "CENPB", "CEP135", "CEP170", "CEP250", "CETN2", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHEK2", "CHERP", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLSTN3", "CLTA", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT2", "CNOT7", "CNP", "COA3", "COIL", "COLEC12", "COLGALT1", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CRYZL1", "CS", "CSE1L", "CSNK1A1", "CSNK2B", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTH", "CTNNA1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWC22", "CYB5B", "CYB5D2", "CYB5R3", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DBN1", "DBNL", "DBT", "DCAF13", "DCAKD", "DCP1A", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCXR", "DDB1", "DDI2", "DDOST", "DDT", "DECR1", "DEK", "DENR", "DERL1", "DERL2", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHRS4", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB4", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH5", "DPM1", "DPP3", "DPYSL2", "DPYSL3", "DPYSL5", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS3L", "DUSP12", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBP", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC4", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF2", "EEFSEC", "EFHD1", "EFL1", "EFTUD2", "EGFR", "EHD1", "EHD4", "EHHADH", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP3", "EMC2", "EMG1", "ENAH", "ENO1", "ENO2", "EPHA7", "EPHX1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERH", "ERMP1", "ERO1A", "ERP29", "ESD", "ESPL1", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXO1", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EZH2", "EZR", "FAHD1", "FAHD2A", "FAM3C", "FAM98A", "FAM98B", "FARSA", "FARSB", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FKBP14", "FKBP1A", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FMR1", "FN3KRP", "FNDC3A", "FOXRED1", "FSCN1", "FSTL1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATAD2A", "GATAD2B", "GATB", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCN1", "GDI1", "GDI2", "GFPT1", "GGH", "GLA", "GLB1", "GLB1L2", "GLDC", "GLMN", "GLO1", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA13", "GNAI2", "GNAI3", "GNB1L", "GNE", "GNG12", "GNG5", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA4", "GOLT1B", "GOPC", "GOSR1", "GOT1", "GOT2", "GPAM", "GPAT4", "GPATCH4", "GPD2", "GPI", "GPKOW", "GPR107", "GPR108", "GPR89B", "GPRASP2", "GRHPR", "GRPEL1", "GRSF1", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP3", "GUF1", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADHB", "HAT1", "HBS1L", "HCCS", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HECTD1", "HECTD3", "HERC2", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIRA", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HM13", "HMBS", "HMGA1", "HMGCL", "HMGN1", "HMGN3", "HMOX1", "HMOX2", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HOOK2", "HP1BP3", "HPRT1", "HPSE", "HS2ST1", "HSD17B10", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HTATIP2", "HTATSF1", "HTRA2", "HUWE1", "IARS", "IARS2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMP4", "IMPAD1", "IMPDH2", "INTS11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "ISCU", "ISOC1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "IVD", "JMJD6", "KARS", "KAT7", "KCTD12", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KDM5A", "KDSR", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0368", "KIF11", "KIF14", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFC1", "KLC1", "KLC2", "KLC4", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRR1", "KYAT3", "L2HGDH", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR3", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LBR", "LDAH", "LDHA", "LDHB", "LDLR", "LENG8", "LETM1", "LGALS3", "LGMN", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LPGAT1", "LRP1", "LRPAP1", "LRRC40", "LRRC47", "LRRC59", "LRRC8C", "LRRFIP2", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM7", "LSM8", "LSS", "LTN1", "LYAR", "LYPLA1", "LZTFL1", "MACF1", "MAGED1", "MAGED2", "MAGT1", "MAN1A1", "MAN1A2", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K4", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCH5", "MARK2", "MARK3", "MARS", "MAT2A", "MAT2B", "MBOAT7", "MCAM", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED17", "MED21", "MED23", "MED24", "MED25", "MED4", "METAP1", "METTL13", "METTL15", "MFAP1", "MFSD3", "MFSD5", "MGEA5", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MIF", "MINPP1", "MIPEP", "MKRN2", "MMAB", "MMS19", "MOB4", "MOGS", "MON2", "MORF4L1", "MORF4L2", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL55", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTHFS", "MTIF2", "MTM1", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MUT", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO6", "NAA10", "NAA15", "NAA50", "NAE1", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCBP1", "NCDN", "NCK1", "NCK2", "NCKIPSD", "NCOA5", "ND1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFB1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFC2", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4", "NEDD4L", "NENF", "NEU1", "NF2", "NFRKB", "NFS1", "NHP2", "NIP7", "NIPBL", "NISCH", "NKRF", "NKTR", "NLN", "NLRX1", "NME1", "NME2", "NME3", "NME7", "NMT1", "NNT", "NOC4L", "NOL6", "NOL9", "NOM1", "NONO", "NOP14", "NOP56", "NOP58", "NOP9", "NOVA1", "NOVA2", "NPEPPS", "NPM1", "NRBP1", "NRDC", "NSDHL", "NSF", "NSFL1C", "NSMCE3", "NSUN2", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDCD2", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUF2", "NUMA1", "NUP107", "NUP153", "NUP155", "NUP160", "NUP210", "NUP214", "NUP37", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "OCRL", "OGDH", "OGFOD3", "OGT", "OLA1", "OPA1", "ORC2", "ORC3", "ORC5", "OSGEP", "OTUB1", "OTUD7B", "OXA1L", "P3H1", "P3H3", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPN1", "PACSIN2", "PAFAH1B2", "PAFAH1B3", "PAIP1", "PAK1IP1", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PAOX", "PAPOLA", "PARG", "PARN", "PARP1", "PARP2", "PAXBP1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH19", "PCK2", "PCMT1", "PCNA", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDP1", "PDPR", "PDS5A", "PDS5B", "PDXK", "PDZD11", "PEBP1", "PECR", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHC2", "PHF10", "PHF14", "PHF3", "PHF6", "PHGDH", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGL", "PIK3C2A", "PIK3R4", "PIN1", "PINX1", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PKP2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNP", "PNPLA6", "PNPO", "PNPT1", "POFUT1", "POFUT2", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3F", "POLRMT", "POMGNT2", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PRAF2", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTCD1", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PUDP", "PUF60", "PUM1", "PURA", "PUS1", "PWP1", "PWWP2A", "PXMP2", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB3GAP1", "RAB3GAP2", "RABGAP1", "RABGGTA", "RABL6", "RAC1", "RACGAP1", "RAD23B", "RAE1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP6", "RBFOX2", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM26", "RBM27", "RBM34", "RBM4", "RBPJ", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "RECQL5", "REEP3", "REEP4", "REEP5", "REL", "REPS1", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RNASEH2A", "RNF14", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPF1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RRM1", "RRM2", "RRS1", "RSF1", "RSL1D1", "RSU1", "RTCA", "RTN4IP1", "RXRB", "S100A10", "S100A11", "S100A13", "SAAL1", "SACM1L", "SAE1", "SAMHD1", "SAP130", "SAP18", "SAP30BP", "SARM1", "SARS", "SARS2", "SART1", "SART3", "SATB2", "SBDS", "SC5D", "SCAF1", "SCAF4", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SDCBP", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC63", "SEH1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT8", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SHC1", "SHMT1", "SHMT2", "SHOC2", "SIGMAR1", "SIN3A", "SIN3B", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC35B2", "SLC38A2", "SLC4A1AP", "SLC4A7", "SLC5A6", "SLC6A15", "SLC7A1", "SLMAP", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC6", "SMN1*", "SMNDC1", "SMPD4", "SNAP23", "SNAP29", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPCS2", "SPCS3", "SPEN", "SPNS1", "SPOUT1", "SPPL2A", "SPR", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", 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sha256:60bf1026eb5ce240c7f8d5200ebb08ae95344b60ae595a8c9608b17e4402e1a9 +size 134290 diff --git a/pharos_dto/consensus.joblib b/pharos_dto/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..4e308941b254be3d7e21610cd6d870227f3ed255 --- /dev/null +++ b/pharos_dto/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:722fa02e65fb4f2633d86adbc29fbd3427df1394a3ee130fd0f7028871969318 +size 159405 diff --git a/pharos_dto/df_merge.tsv b/pharos_dto/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..6da8e96d0d0628c7d5957cd06db11d06f385b794 --- /dev/null +++ b/pharos_dto/df_merge.tsv @@ -0,0 +1,12 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Signaling 10 20 3.0763837813498567 0.0020952796613615 5.66747572815534 18.009708737864077 1.330299096012152 0.2668377480945127 2.507969905227609 1.6994867622232877 1.0107551340834326 0.2926688105318188 0.2935004598938068 0.3467229085425889 0.5741114914523541 0.3618702667758764 0.0645148528391164 +Receptor 7 26 2.663622059086876 0.0077304360997771 8.25242718446602 27.344660194174757 1.739519175745715 0.1905542238199536 2.855648283399814 4.245230977176689 1.1861053756197322 0.2707159726336181 0.374197397277918 0.4014813083941581 0.6426690076912178 0.0042468708986693 0.1451282622080898 +Calcium-binding protein 7 22 2.535739591512259 0.0112210140700903 6.135922330097087 18.021844660194176 1.3650952896045327 0.2072953623045914 2.3371152398743247 2.2037057261181348 1.237653756718734 0.2545563939054063 0.0023601083243512 0.0204708743585679 0.0096938597365547 0.0001101759586877 0.0015279037069893 +Phosphatase inhibitor 2 6 2.446892334949012 0.0144093875435016 2.728155339805826 6.172330097087379 0.9635556310357324 0.3115567860102488 1.3049136024465862 0.9562829575598468 1.0731560672377305 0.3073869469134278 0.0123221163543065 1.0 0.1265462710440741 0.0042425564235442 0.0280386150660574 +Phosphatase modulator 2 8 2.4138335348474524 0.0157856725672556 3.2184466019417477 8.21116504854369 0.7670748435043443 0.3739387538838107 1.5675252632835437 1.2965868569491776 1.0363110244436506 0.3073927580302922 0.0400077618678618 1.0 0.2223047329091382 0.0244664942800011 0.1309583783231107 +SLC25 family of mitochondrial transporters 4 21 2.2912139971222376 0.0219510398088893 9.148058252427184 20.71359223300971 2.0411027534642088 0.1411881998864352 5.368907349966936 1.8276489510009888 1.309103123363054 0.2428184236965967 0.0103166972333632 0.1635258499471353 0.048990890514732 0.0602711275874904 0.0324377486516598 +Calmodulin 11 17 2.169208893937409 0.0300668282200324 5.330097087378641 14.50728155339806 1.3338669185027796 0.2094989649985028 2.1356354617596836 1.8597539737980884 1.176586593960994 0.2465515447823433 0.006884119919632 0.1430638950507344 0.0376249374527164 0.0001038396922648 0.0007278251765531 +Intracellular calcium-sensing protein 11 17 2.169208893937409 0.0300668282200324 5.330097087378641 14.50728155339806 1.3338669185027796 0.2094989649985028 2.1356354617596836 1.8597539737980884 1.176586593960994 0.2465515447823433 0.006884119919632 0.1430638950507344 0.0376249374527164 0.0001038396922648 0.0007278251765531 +Mitochondrial nucleotide transporter subfamily 1 8 2.0981148217669663 0.0358950035538805 4.216019417475728 9.065533980582524 1.5870110662923598 0.1668197633609344 2.720728714423222 1.1029864386277723 1.1616247375257451 0.2431804664231326 0.0141047644752725 0.0697581245313758 0.0088504827764808 0.050241067872642 0.1641299211995837 +F-type and V-type ATPases 5 16 2.062781456864801 0.0391333965870086 4.995145631067961 15.616504854368932 0.6819760311565471 0.3553057475304781 2.5561606009064737 1.187932616128487 1.149561543758102 0.2999604229905949 0.0026629920200185 0.0053672672920639 0.0013262573806951 0.0175758241055335 0.0236194052560011 +Growth factor 3 5 2.026526465367419 0.0427108634887472 1.4587378640776698 4.927184466019417 0.569518613320005 0.5011207143101012 1.240789898436257 0.6715717218754621 0.8148940327825237 0.3038203600724809 0.1792312731033967 1.0 1.0 0.3258327648280404 0.0401461367370898 diff --git a/pharos_dto/metrics.json b/pharos_dto/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..f6814967206c06da7d92c16c4162422791a4d7ad --- /dev/null +++ b/pharos_dto/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3381, + "annotations_size": 2124, + "title": "Average number of proteins per term", + "value": 3.134651600753296 +} \ No newline at end of file diff --git a/pharos_dto/paths.json b/pharos_dto/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..526ce424f2c37230e9d210a531b6701cef8a9179 --- /dev/null +++ b/pharos_dto/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_dto/fragment/C317/C317_val_log2fc"} \ No newline at end of file diff --git a/pharos_dto/result.tsv b/pharos_dto/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..9034a3709ee54c97f470cad896bde2015464360e --- /dev/null +++ b/pharos_dto/result.tsv @@ -0,0 +1,81 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Signaling 0.69406719519381 3.0763837813498567 0.0020952796613615 0.9883801787742126 0.4536866634465707 20 Q5JRA6,Q99627,Q07820,Q7Z4V5,O15173,O14641,Q8WUJ1,P51858,P43490,Q96PC5 10 +Receptor 0.6309687194262702 2.663622059086876 0.0077304360997771 0.9999999305903546 0.4536866634465707 26 O75381,P57105,Q567V2,Q9NR77,P41214,A6NIH7,Q8WTV0 7 +Calcium-binding protein 0.6138643945092889 2.535739591512259 0.0112210140700903 0.9999999999610272 0.4536866634465707 22 P0DP25,Q8IYU8,P80303,O43852,Q14257,P43307,Q9BPX6 7 +Phosphatase inhibitor 0.87079660108517 2.446892334949012 0.0144093875435016 0.9999999999999593 0.4536866634465707 6 Q99733,Q01105 2 +Phosphatase modulator 0.8182733484919775 2.4138335348474524 0.0157856725672556 0.999999999999998 0.4536866634465707 8 Q99733,Q01105 2 +SLC25 family of mitochondrial transporters 0.5792617613881876 2.2912139971222376 0.0219510398088893 1.0 0.4536866634465707 21 Q9UBX3,O43772,Q9H2D1,Q70HW3 4 +Calmodulin 0.6116589385147095 2.1692088939374092 0.0300668282200324 1.0 0.4536866634465707 17 Q99584,P0DP25,Q8IYU8,Q9BRK5,P80303,Q15293,Q14257,O43852,P60660,P41208,Q9BPX6 11 +Intracellular calcium-sensing protein 0.6116589385147095 2.1692088939374092 0.0300668282200324 1.0 0.4536866634465707 17 Q99584,P0DP25,Q8IYU8,Q9BRK5,P80303,Q15293,Q14257,O43852,P60660,P41208,Q9BPX6 11 +Mitochondrial nucleotide transporter subfamily 0.750040573258181 2.0981148217669663 0.0358950035538805 1.0 0.4536866634465707 8 Q70HW3 1 +F-type and V-type ATPases 0.6090595438271702 2.062781456864801 0.0391333965870086 1.0 0.4536866634465707 16 P00846,Q9Y487,Q93050,P06576,Q9Y5K8 5 +Growth factor 0.8222856968730314 2.026526465367419 0.0427108634887472 1.0 0.4536866634465707 5 Q96PC5,Q7Z4V5,P51858 3 +Extracellular matrix glycoprotein 0.7969482875388014 1.9197477441264328 0.0548897703519128 1.0 0.4536866634465707 5 Q9Y2T2,Q8IVL6 2 +Protein arginine methyltransferase 0.8296632140007942 1.83513301764586 0.0664859828116584 1.0 0.4536866634465707 4 O60678 1 +SLC superfamily of solute carriers 0.5001403774192845 1.8030442011481496 0.0713812731968142 1.0 0.4536866634465707 46 P55011,O43772,Q9H2D1,Q70HW3,O95563,O95202,Q8TB61,Q96QD8,Q9HC07,Q9Y6M7,Q8IXU6,O43808,P30825,Q9BSK2,Q9UBX3,Q9Y6C9,Q8NEW0 17 +SNARE protein 0.6078661951625577 1.8016706126600537 0.0715972443053003 1.0 0.4536866634465707 12 O95249,O43752,O95721,Q13277,Q9P2W9 5 +Extracellular structure 0.6466565668110771 1.7862416958485718 0.074060132617042 1.0 0.4536866634465707 10 Q9Y2T2,Q8IVL6,Q32P28,Q92791 4 +Guanyl-nucleotide exchange factor 0.8846301584189533 1.6848396750729118 0.092019507909836 1.0 0.4738516876845413 3 Q14C86 1 +Glycosyltransferase 0.5219818913089511 1.6627592088270708 0.0963606449126854 1.0 0.4759661602189045 18 Q8N128,Q10472,P04843,Q9BT22,Q9Y2G5,P46977,P46976,Q10471,Q16739 9 +F-type ATPase 0.6561948707777469 1.645822779391514 0.0998002509698852 1.0 0.4759661602189045 8 P00846,P06576 2 +Transporter 0.4085318757781544 1.575882063340828 0.1150529853831692 1.0 0.4860620015731695 196 P55011,Q70HW3,O95563,Q96QD8,Q9BVK6,Q99805,Q15388,O43808,Q8IXU6,Q13190,P49257,Q9BQE5,P50542,P30825,Q8NEW0,P24390,P00846,O95249,O43772,Q8NFH4,P05023,O95202,O43752,Q9Y3A6,Q9HC07,Q9Y6M7,Q08379,Q93050,Q9BQT8,O95721,Q92572,Q9C0E2,Q99567,Q13277,Q15363,Q8N1F7,P06576,Q9Y6C9,P98194,Q03518,Q9H2D1,Q9HD45,Q8TB61,Q9Y487,O60749,O43731,Q15075,P24539,P35606,Q9P2W9,P21281,Q92973,P49755,Q8TAG9,Q96A65,O43760,Q92544,O60763,P16615,Q8WUX9,P54105,Q9BSK2,Q9UBX3,Q9Y5K8,Q96QK1,Q8TEX9 66 +V-type ATPase 0.6413743427174137 1.5726735316776077 0.115794431636546 1.0 0.4860620015731695 8 Q93050 1 +Oxidase 0.4811420497846526 1.5586975359432529 0.1190679852659342 1.0 0.4904393950216342 22 O75880,Q15067,Q6ZRP7,Q15800,O43169,O15254,O15260,P14406 8 +AKT family 0.9508730393607586 1.4126083353837664 0.1577709168433121 1.0 0.533538281590178 2 P31751 1 +G-protein modulator 0.4584590721806866 1.3600526347727449 0.1738132682385507 1.0 0.5426948956151688 29 P53365,Q9Y4G8,Q6WCQ1,O00410,Q8IUD2,Q14C86,Q96D71,Q7L576,P49815,Q15437 10 +AGC group 0.5538635378787871 1.2890647022435593 0.1973755936199035 1.0 0.5671080839812629 10 P31749,P31751 2 +Actin binding motor protein 0.5774056278245198 1.253050034830726 0.2101874981300762 1.0 0.5824234251687408 8 P67936,P09493 2 +Replication origin binding protein 0.6836386546199887 1.231728756571893 0.218050424039548 1.0 0.5907386488010203 4 O75419,Q13416 2 +Immune response 0.5802520654626125 1.1397341521160702 0.2543970742796451 1.0 0.6283016113604257 6 P78318 1 +Ca2+-ATPases 0.7438772744587039 1.1330113200048468 0.2572094995854694 1.0 0.6285329406770639 3 P16615 1 +P-type ATPases 0.5628119691951132 1.1147316788468002 0.2649654215186361 1.0 0.637357367276991 7 P16615,P05023 2 +Translation initiation factor 0.4207721387901705 1.1033410653597069 0.2698790795997305 1.0 0.6440709719885704 20 O75153 1 +SLC35 family of nucleotide sugar transporters 0.8659366676531532 1.0825692474515205 0.2789996634204206 1.0 0.6542424980824609 2 Q8IXU6 1 +Unclassified protein 0.4254042017726214 1.0507217966643998 0.2933863821788398 1.0 0.6686187508024204 19 Q9BRR6,Q9HBU6 2 +Mitochondrial amino acid transporter subfamily 0.5488311910454768 0.9928846862260772 0.3207661534363679 1.0 0.6988038994977898 6 O43772,O75746,Q8TBP6,Q9Y619 4 +Phospholipase 0.6208940341320095 0.9712691293590928 0.3314142772607309 1.0 0.7081729626778597 4 Q8N2A8,Q8NCC3 2 +Cell-cell junction 0.5834861611010588 0.8189551384859866 0.4128120093493805 1.0 0.7671152299720773 4 Q16625 1 +Reductase 0.4152869398134176 0.7915404753252155 0.428628666651843 1.0 0.7763286729337728 16 Q14739,Q9UDW1,Q15392,P31350 4 +Metalloprotease 0.3894293379355846 0.7874975606498429 0.4309906558323129 1.0 0.776332096201679 39 Q9BYT8,Q6P179,Q9Y4W6,P22695,Q9NZ08,P51665,Q5JRX3,P55786,O75844,P52888,Q10713,O15372 12 +Esterase 0.4347472945530217 0.7825753658975264 0.4338765120963868 1.0 0.7776824571246629 12 Q969T7 1 +Tight junction 0.6493861363684217 0.7719251572196008 0.4401587563254225 1.0 0.7856278978447039 3 Q16625 1 +RSK family 0.7611719443622403 0.6961257886688488 0.4863500575484782 1.0 0.8152647712273192 2 Q15418 1 +RSK subfamily 0.7611719443622403 0.6961257886688488 0.4863500575484782 1.0 0.8152647712273192 2 Q15418 1 +Ion channel 0.4438079002898379 0.6933398229310608 0.4880963173100723 1.0 0.8156700062679729 10 Q9C0H2,Q96S66,P0CG08 3 +Oxidoreductase 0.3053053721600077 0.6906220577320581 0.4898030820280143 1.0 0.8169229815473842 120 P30837,Q16850,P31350,Q9UDW1,Q13423,Q8N0U8,Q15067,O94788,P00403,P03886,O43169,Q15392,P14406,O15254,O15260,P43304,O95831,Q8N4Q0 18 +Protein methyltransferase 0.444501492102716 0.6414504220940924 0.5212300822596312 1.0 0.8336881346672355 9 O60678,Q8WTS6 2 +Writer 0.4331464354247732 0.6375138265710624 0.5237902066348061 1.0 0.8346158026051989 10 O60678,Q8WTS6 2 +Aspartic protease 0.5315883393359254 0.6158442172035018 0.5379973409713228 1.0 0.843325721197852 4 Q5BJF2 1 +CDK1 subfamily 0.7090855282628034 0.5226485295115345 0.6012188624355024 1.0 0.8782591910680928 2 P06493 1 +Translation factor 0.3474573051193563 0.4932984375570656 0.6218017322149954 1.0 0.8881687150132146 26 O75153 1 +Lysine-specific demethylase 0.6913287955016321 0.4678272413296803 0.6399081380743925 1.0 0.8953655370685175 2 Q8NB78 1 +ROCK subfamily 0.6889612311334757 0.4607101509576802 0.6450065712237312 1.0 0.8960065122820177 2 O75116 1 +DMPK family 0.6889612311334757 0.4607101509576802 0.6450065712237312 1.0 0.8960065122820177 2 O75116 1 +Major histocompatibility complex antigen 0.5480679104586438 0.4258459058879164 0.6702201340094853 1.0 0.9067181940357624 3 Q9NX40 1 +Enzyme modulator 0.2846882780529985 0.3614456279651782 0.7177663439452437 1.0 0.925610557409987 124 O95155,Q9Y4G8,Q9BV73,P46379,Q96P70,O60313,Q96ED9,Q96D71,O14737,P07942,P55209,Q8NHH9,O00429,O60271,Q01105,Q7L576,P53365,Q66GS9,P49815,Q15437,Q99733,Q8IUD2,Q9Y2I1,Q14C86,Q14141 25 +Protein phosphatase 0.3672927173773482 0.3544021669102533 0.7230375108567535 1.0 0.925610557409987 11 Q9P0J1,P10586 2 +Membrane trafficking regulatory protein 0.3175024152718063 0.3223938737398263 0.7471543247288119 1.0 0.9327380773979498 21 P24390 1 +ERK subfamily 0.6226694288251016 0.2827728786802313 0.7773509458392995 1.0 0.9418786926864094 2 P27361 1 +SRPK family 0.6176383545427697 0.2711325995654838 0.7862890494788264 1.0 0.9452049397075024 2 P78362 1 +CDK family 0.3609206637723319 0.2593925927705512 0.7953323442998643 1.0 0.9474402127273762 9 P24941,P11802,P21127,P06493 4 +MAPK family 0.4804618117229231 0.2428762609374652 0.8081012560517 1.0 0.9484588034304252 3 P28482,P27361 2 +Phosphatase 0.3129421462966307 0.2082704199337847 0.8350178266879551 1.0 0.9484588034304252 32 Q9NPH0,Q9NX62,P30154,Q9P0J1,Q86YN1,P10586 6 +Chaperonin 0.3411938674592424 0.2050915577903966 0.83750059215089 1.0 0.9484588034304252 10 P49368 1 +Protease 0.2670731883253404 0.1857168017387839 0.8526668516591147 1.0 0.9484588034304252 116 Q9Y4E8,Q9UNW9,P67812,Q9H3G5,Q96RU2,P22695,Q9Y4W6,P17812,Q06203,Q10713,Q8TCT9,Q9NZ08,P55786,P13798,Q9Y3P9,Q9Y4P1,Q9Y6M1,Q5BJF2,P51665,P61978,P52888,O15372,Q96AE4,Q9BYT8,Q6P179,Q5JRX3,O75844,Q9NRF8,Q96I24,Q96K76,P42785 31 +Tubulin 0.3407407407407445 0.1526431394111993 0.8786797032852867 1.0 0.9484588034304252 6 P68371,P07437,Q13509,Q13885,Q9BUF5 5 +Na+/K+-ATPases 0.4339232567472304 0.1487147639325831 0.8817787108564861 1.0 0.9484588034304252 3 P05023 1 +Kinase activator 0.3385988952891094 0.1467465576557681 0.883332068677569 1.0 0.9484588034304252 6 O95163,P20248,Q16543 3 +Nucleotide phosphatase 0.3287804671453244 0.1296404858449121 0.8968508704483749 1.0 0.9499747658169742 8 Q8IWA4,O43681,P49902,Q9H857 4 +STE7 family 0.4980763539508806 0.0815721299148216 0.9349869645215618 1.0 0.9593779288134286 2 Q02750 1 +Microtubule binding motor protein 0.2892997406137103 0.077821434786096 0.937970095660992 1.0 0.9609710512773232 17 Q15058,O60333,Q13561,P33176 4 +SLC56 Sideroflexins 0.4921574430304901 0.0763659804550805 0.93912793420937 1.0 0.9609710512773232 2 Q96NB2 1 +Chromodomain 0.3157582938388543 0.0653095246612894 0.9479275589536358 1.0 0.9610492292207744 5 P83916,Q13185,Q14781,Q99549 4 +Deacetylase 0.4664101805267909 0.0575543175853827 0.9541036386009228 1.0 0.96684929789521 2 O75182 1 +Immunoglobulin fold transcription factor 0.4598993785143618 0.0537071373586019 0.9571684962214496 1.0 0.9694925541127128 2 Q04864 1 +Chaperone 0.2927622424460702 0.0381430749429927 0.9695736074437756 1.0 0.9806544486717046 41 Q9UHV9,P78371,O60476,P33908,O00170,P49368 6 +Antibacterial response protein 0.4072210713228832 0.0332861122324179 0.973446428456956 1.0 0.9841029100631006 2 P40222 1 +Non-motor microtubule binding protein 0.2785967354278638 0.0309802084468181 0.9752853234675588 1.0 0.9854928768054688 17 O94901,Q3KQU3,Q15555,Q9UH99,Q9BSJ2 5 +Mutase 0.3169576797869272 0.0237353456315764 0.9810637122040512 1.0 0.9903894128904016 2 P00492 1 +Lysine demethylase 0.2913597447711672 0.0227629734066784 0.9818393433073856 1.0 0.990701551156716 3 Q8NB78 1 +Heterotrimeric G-protein 0.2680106121459689 0.0033467212983991 0.9973297077314855 1.0 1.0 6 Q8NHH9 1 +Lipid kinase 0.2633293838862515 0.0007360675509926 0.9994127031183876 1.0 1.0 5 Q9BTU6,O00443,Q8TBX8,P42356 4 diff --git a/pharos_dto/selections.json b/pharos_dto/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..51411d8a8f1d0053d43c9bcbd6ff3a6ec696e7b0 --- /dev/null +++ b/pharos_dto/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "10 kDa heat shock protein, mitochondrial", "116 kDa U5 small nuclear ribonucleoprotein component", "14-3-3 protein beta/alpha", "14-3-3 protein epsilon", "14-3-3 protein eta", "14-3-3 protein gamma", "14-3-3 protein theta", "14-3-3 protein zeta/delta", "2',3'-cyclic-nucleotide 3'-phosphodiesterase", "2',5'-phosphodiesterase 12", "2,4-dienoyl-CoA reductase, mitochondrial", "2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial", "2-hydroxyacyl-CoA lyase 1", "26S proteasome non-ATPase regulatory subunit 1", "26S proteasome non-ATPase regulatory subunit 12", "26S proteasome non-ATPase regulatory subunit 13", "26S proteasome non-ATPase regulatory subunit 14", "26S proteasome non-ATPase regulatory subunit 2", "26S proteasome non-ATPase regulatory subunit 3", "26S proteasome non-ATPase regulatory subunit 4", "26S proteasome non-ATPase regulatory subunit 7", "26S proteasome non-ATPase regulatory subunit 8", "26S proteasome regulatory subunit 10B", "26S proteasome regulatory subunit 4", "26S proteasome regulatory subunit 6A", "26S proteasome regulatory subunit 6B", "26S proteasome regulatory subunit 7", "26S proteasome regulatory subunit 8", "28S ribosomal protein S11, mitochondrial", "28S ribosomal protein S16, mitochondrial", "28S ribosomal protein S2, mitochondrial", "28S ribosomal protein S27, mitochondrial", "28S ribosomal protein S29, mitochondrial", "28S ribosomal protein S35, mitochondrial", "28S ribosomal protein S5, mitochondrial", "28S ribosomal protein S7, mitochondrial", "3'(2'),5'-bisphosphate nucleotidase 1", "3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase", "3-hydroxyacyl-CoA dehydrogenase type-2", "3-hydroxyisobutyrate dehydrogenase, mitochondrial", "3-hydroxyisobutyryl-CoA hydrolase, mitochondrial", "3-ketoacyl-CoA thiolase, mitochondrial", "3-ketoacyl-CoA thiolase, peroxisomal", "3-mercaptopyruvate sulfurtransferase", "39S ribosomal protein L1, mitochondrial", "39S ribosomal protein L11, mitochondrial", "39S ribosomal protein L12, mitochondrial", "39S ribosomal protein L13, mitochondrial", "39S ribosomal protein L14, mitochondrial", "39S ribosomal protein L17, mitochondrial", "39S ribosomal protein L19, mitochondrial", "39S ribosomal protein L2, mitochondrial", "39S ribosomal protein L20, mitochondrial", "39S ribosomal protein L21, mitochondrial", "39S ribosomal protein L23, mitochondrial", "39S ribosomal protein L24, mitochondrial", "39S ribosomal protein L38, mitochondrial", "39S ribosomal protein L39, mitochondrial", "39S ribosomal protein L43, mitochondrial", "39S ribosomal protein L44, mitochondrial", "39S ribosomal protein L47, mitochondrial", "39S ribosomal protein L48, mitochondrial", "39S ribosomal protein L49, mitochondrial", "39S ribosomal protein L9, mitochondrial", "39S ribosomal protein S18a, mitochondrial", "4-aminobutyrate aminotransferase, mitochondrial", "4-trimethylaminobutyraldehyde dehydrogenase", "40S ribosomal protein S10", "40S ribosomal protein S11", "40S ribosomal protein S12", "40S ribosomal protein S13", "40S ribosomal protein S14", "40S ribosomal protein S15", "40S ribosomal protein S15a", "40S ribosomal protein S17", "40S ribosomal protein S18", "40S ribosomal protein S19", "40S ribosomal protein S2", "40S ribosomal protein S20", "40S ribosomal protein S21", "40S ribosomal protein S23", "40S ribosomal protein S24", "40S ribosomal protein S26", "40S ribosomal protein S28", "40S ribosomal protein S3", "40S ribosomal protein S3a", "40S ribosomal protein S4, X isoform", "40S ribosomal protein S5", "40S ribosomal protein S6", "40S ribosomal protein S7", "40S ribosomal protein S8", "40S ribosomal protein S9", "40S ribosomal protein SA", "45 kDa calcium-binding protein", "4F2 cell-surface antigen heavy chain", "5'-AMP-activated protein kinase catalytic subunit alpha-1", "5'-AMP-activated protein kinase subunit gamma-1", "5'-nucleotidase domain-containing protein 1", "5'-nucleotidase domain-containing protein 2", "5-formyltetrahydrofolate cyclo-ligase", "55 kDa erythrocyte membrane protein", "6-phosphogluconate dehydrogenase, decarboxylating", "6-phosphogluconolactonase", "60 kDa SS-A/Ro ribonucleoprotein", "60S ribosomal protein L10", "60S ribosomal protein L10a", "60S ribosomal protein L11", "60S ribosomal protein L12", "60S ribosomal protein L13", "60S ribosomal protein L13a", "60S ribosomal protein L14", "60S ribosomal protein L15", "60S ribosomal protein L18", "60S ribosomal protein L19", "60S ribosomal protein L21", "60S ribosomal protein L22", "60S ribosomal protein L23", "60S ribosomal protein L23a", "60S ribosomal protein L24", "60S ribosomal protein L26", "60S ribosomal protein L27", "60S ribosomal protein L27a", "60S ribosomal protein L28", "60S ribosomal protein L29", "60S ribosomal protein L3", "60S ribosomal protein L30", "60S ribosomal protein L31", "60S ribosomal protein L32", "60S ribosomal protein L35", "60S ribosomal protein L35a", "60S ribosomal protein L36", "60S ribosomal protein L36a", "60S ribosomal protein L37", "60S ribosomal protein L38", "60S ribosomal protein L5", "60S ribosomal protein L6", "60S ribosomal protein L7", "60S ribosomal protein L7-like 1", "60S ribosomal protein L7a", "60S ribosomal protein L8", "60S ribosomal protein L9", "7,8-dihydro-8-oxoguanine triphosphatase", "7-dehydrocholesterol reductase", "7-methylguanosine phosphate-specific 5'-nucleotidase", "A-kinase anchor protein 1, mitochondrial", "ABCB subfamily", "ABCC subfamily", "ABCD subfamily of peroxisomal ABC transporters", "ADP-dependent glucokinase", "ADP-sugar pyrophosphatase", "ADP/ATP translocase 1", "ADP/ATP translocase 2", "ADP/ATP translocase 3", "AFG3-like protein 2", "AGC group", "AH receptor-interacting protein", "AK1 subfamily", "AK2 subfamily", "AK3 subfamily", "AKT family", "AMP deaminase 2", "AMPK subfamily", "AP-1 complex subunit beta-1", "AP-1 complex subunit gamma-1", "AP-1 complex subunit mu-1", "AP-2 complex subunit alpha-1", "AP-2 complex subunit alpha-2", "AP-2 complex subunit beta", "AP-2 complex subunit mu", "AP-2 complex subunit sigma", "AP-3 complex subunit beta-1", "AP-3 complex subunit delta-1", "AP-3 complex subunit mu-1", "AP-3 complex subunit sigma-1", "ATP synthase F(0) complex subunit B1, mitochondrial", "ATP synthase mitochondrial F1 complex assembly factor 1", "ATP synthase subunit a", "ATP synthase subunit alpha, mitochondrial", "ATP synthase subunit beta, mitochondrial", "ATP synthase subunit d, mitochondrial", "ATP synthase subunit e, mitochondrial", "ATP synthase subunit f, mitochondrial", "ATP synthase subunit gamma, mitochondrial", "ATP-binding cassette sub-family B member 10, mitochondrial", "ATP-binding cassette sub-family B member 7, mitochondrial", "ATP-binding cassette sub-family B member 8, mitochondrial", "ATP-binding cassette sub-family D member 3", "ATP-binding cassette sub-family D member 4", "ATP-binding cassette sub-family F member 1", "ATP-binding cassette sub-family F member 2", "ATP-binding cassette transporter family", "ATP-citrate synthase", "ATP-dependent 6-phosphofructokinase, muscle type", "ATP-dependent 6-phosphofructokinase, platelet type", "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial", "ATP-dependent DNA helicase Q1", "ATP-dependent DNA helicase Q4", "ATP-dependent DNA helicase Q5", "ATP-dependent PFK group I subfamily", "ATP-dependent RNA helicase A", "ATP-dependent RNA helicase DHX29", "ATP-dependent RNA helicase DHX8", "ATP-dependent zinc metalloprotease YME1L1", "ATPase ASNA1", "ATPase family AAA domain-containing protein 2", "ATPase family AAA domain-containing protein 3A", "ATPase family AAA domain-containing protein 3B", "ATPase inhibitor, mitochondrial", "AUR family", "Acetoacetyl-CoA synthetase", "Acetolactate synthase-like protein", "Acetyl-CoA acetyltransferase, cytosolic", "Acetyl-CoA acetyltransferase, mitochondrial", "Acetyltransferase", "Acid ceramidase", "Acidic leucine-rich nuclear phosphoprotein 32 family member B", "Acidic leucine-rich nuclear phosphoprotein 32 family member E", "Aconitate hydratase, mitochondrial", "Actin and actin related protein", "Actin binding motor protein", "Actin family cytoskeletal protein", "Actin-like protein 6A", "Actin-related protein 10", "Actin-related protein 2", "Actin-related protein 2/3 complex subunit 1A", "Actin-related protein 2/3 complex subunit 3", "Actin-related protein 2/3 complex subunit 4", "Actin-related protein 3", "Actin-related protein 6", "Acyl-CoA dehydrogenase family member 11", "Acyl-CoA dehydrogenase family member 9, mitochondrial", "Acyl-CoA synthetase family member 3, mitochondrial", "Acyl-CoA-binding domain-containing protein 5", "Acyl-coenzyme A thioesterase 8", "Acyl-coenzyme A thioesterase 9, mitochondrial", "Acylamino-acid-releasing enzyme", "Acylpyruvase FAHD1, mitochondrial", "Acyltransferase", "Adenosine 3'-phospho 5'-phosphosulfate transporter 1", "Adenosine deaminase", "Adenosine kinase", "Adenosylhomocysteinase", "Adenylate kinase 2, mitochondrial", "Adenylate kinase 4, mitochondrial", "Adenylate kinase family", "Adenylate kinase isoenzyme 1", "Adenylate kinase isoenzyme 6", "Adenylosuccinate lyase", "Adenylosuccinate synthetase isozyme 2", "Adenylyl cyclase-associated protein 1", "Afadin", "Aflatoxin B1 aldehyde reductase member 2", "Alanine--tRNA ligase, cytoplasmic", "Alanine--tRNA ligase, mitochondrial", "Alanine/serine/cysteine transporter subfamily", "Alanyl-tRNA editing protein Aarsd1", "Alcohol dehydrogenase [NADP(+)]", "Alcohol dehydrogenase class-3", "Aldehyde dehydrogenase X, mitochondrial", "Aldehyde dehydrogenase, mitochondrial", "Aldose 1-epimerase", "Aldose reductase", "Alpha-adducin", "Alpha-aminoadipic semialdehyde dehydrogenase", "Alpha-centractin", "Alpha-enolase", "Alpha-globin transcription factor CP2", "Alpha-soluble NSF attachment protein", "Alpha-taxilin", "Amidophosphoribosyltransferase", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 1", "Aminoacyl-tRNA synthetase", "Amyloid-beta A4 protein", "Amyloid-like protein 2", "Anaphase-promoting complex subunit 1", "Ancient ubiquitous protein 1", "Anion channel tweety (tweety) family", "Annexin", "Anoctamin-6", "Antibacterial response protein", "Antigen peptide transporter 1", "Antigen peptide transporter 2", "Apolipoprotein", "Apolipoprotein L2", "Apoptosis regulator BAX", "Apoptosis-inducing factor 1, mitochondrial", "Apoptosis-stimulating of p53 protein 2", "Arfaptin-1", "Arfaptin-2", "Arginase-2, mitochondrial", "Armadillo repeat protein deleted in velo-cardio-facial syndrome", "Asparagine synthetase [glutamine-hydrolyzing]", "Asparagine--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, mitochondrial", "Aspartic protease", "Ataxin-2-like protein", "Atlastin-2", "Atp-dependent 6-phosphofructokinase, liver type", "Atypical SLC22B subfamily", "Atypical group", "Aurora kinase b", "B-cell receptor-associated protein 31", "BTB/POZ domain-containing protein KCTD12", "BUB family", "BUB3-interacting and GLEBS motif-containing protein ZNF207", "Basic leucine zipper and W2 domain-containing protein 1", "Basic leucine zipper and W2 domain-containing protein 2", "Bcl-2-associated transcription factor 1", "Beta-adducin", "Beta-galactosidase", "Beta-galactosidase-1-like protein 2", "Beta-hexosaminidase subunit alpha", "Beta-hexosaminidase subunit beta", "Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1", "Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase", "Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6", "Bifunctional glutamate/proline--tRNA ligase", "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial", "Bifunctional purine biosynthesis protein PURH", "Biliverdin reductase A", "Biotin--protein ligase", "Bleomycin hydrolase", "Brain-specific angiogenesis inhibitor 1-associated protein 2", "Branched-chain-amino-acid aminotransferase, mitochondrial", "Breast cancer type 1 susceptibility protein", "Bromodomain", "Bromodomain-containing protein 2", "Bromodomain-containing protein 3", "Bromodomain-containing protein 4", "Bromodomain-containing protein 7", "C-1-tetrahydrofolate synthase, cytoplasmic", "C-Jun-amino-terminal kinase-interacting protein 4", "C-terminal-binding protein 1", "C-terminal-binding protein 2", "C2H2 zinc finger transcription factor", "CAAX prenyl protease 1 homolog", "CAD protein", "CAMK group", "CAMK1 family", "CAMK2 family", "CAMKL family", "CASK family", "CCAAT/enhancer-binding protein zeta", "CCK4 family", "CCR4-NOT transcription complex subunit 1", "CCR4-NOT transcription complex subunit 2", "CCR4-NOT transcription complex subunit 7", "CD166 antigen", "CD2 antigen cytoplasmic tail-binding protein 2", "CDK family", "CDK1 subfamily", "CDK4 subfamily", "CDK5 subfamily", "CDK9 subfamily", "CDKN2A-interacting protein", "CK1 family", "CK1 group", "CK2 family", "CLIP-associating protein 1", "CLIP-associating protein 2", "CMGC group", "COP9 signalosome complex subunit 3", "COP9 signalosome complex subunit 5", "COP9 signalosome complex subunit 6", "COP9 signalosome complex subunit 8", "CRK7 subfamily", "CSK family", "CTP synthase 1", "CTP synthase 2", "Ca2+-ATPases", "Cadherin", "Calcium homeostasis endoplasmic reticulum protein", "Calcium uniporter protein, mitochondrial", "Calcium uptake protein 1, mitochondrial", "Calcium uptake protein 2, mitochondrial", "Calcium-binding mitochondrial carrier protein Aralar1", "Calcium-binding mitochondrial carrier protein Aralar2", "Calcium-binding mitochondrial carrier protein SCaMC-1", "Calcium-binding protein", "Calcium-binding protein 39", "Calcium-dependent chloride channel (ca-clc) family", "Calcium-regulated heat-stable protein 1", "Calcium-transporting ATPase type 2C member 1", "Calcium/calmodulin-dependent protein kinase type 1", "Calcium/calmodulin-dependent protein kinase type ii subunit gamma", "Calcyclin-binding protein", "Calmegin", "Calmodulin", "Calmodulin-3", "Calnexin", "Calpain-1 catalytic subunit", "Calpain-2 catalytic subunit", "Calponin-2", "Calponin-3", "Calreticulin", "Calsyntenin-3", "Calumenin", "Camp-dependent protein kinase catalytic subunit alpha", "Cancer-related nucleoside-triphosphatase", "Caprin-1", "Carbohydrate kinase", "Carbohydrate sulfotransferase 14", "Carnitine O-palmitoyltransferase 1, liver isoform", "Carnitine O-palmitoyltransferase 2, mitochondrial", "Cartilage-associated protein", "Casein kinase II subunit alpha'", "Casein kinase i isoform alpha", "Casein kinase ii subunit beta", "Catechol O-methyltransferase", "Catechol O-methyltransferase domain-containing protein 1", "Catenin alpha-1", "Catenin delta-1", "Cathepsin B", "Cation-independent mannose-6-phosphate receptor", "Cell adhesion", "Cell cycle and apoptosis regulator protein 2", "Cell division control protein 42 homolog", "Cell division control protein 45 homolog", "Cell division cycle and apoptosis regulator protein 1", "Cell division cycle protein 20 homolog", "Cell surface glycoprotein MUC18", "Cell-cell junction", "Cellular structure", "Cellular tumor antigen p53", "Centrin-2", "Centromere/kinetochore protein zw10 homolog", "Centrosomal protein of 135 kDa", "Centrosomal protein of 170 kDa", "Centrosome-associated protein CEP250", "Ceramide glucosyltransferase", "Chaperone", "Chaperonin", "Charged multivesicular body protein 4b", "Charged multivesicular body protein 5", "Charged multivesicular body protein 6", "Charged multivesicular body protein 7", "Chitobiosyldiphosphodolichol beta-mannosyltransferase", "Chloride channel CLIC-like protein 1", "Chloride channel family", "Chloride intracellular channel protein 1", "Chloride intracellular channel protein 4", "Choline kinase alpha", "Choline/ethanolamine kinase family", "Chromatin accessibility complex protein 1", "Chromatin assembly factor 1 subunit A", "Chromatin assembly factor 1 subunit B", "Chromatin target of PRMT1 protein", "Chromatin/chromatin-binding protein", "Chromobox protein homolog 1", "Chromobox protein homolog 2", "Chromobox protein homolog 3", "Chromobox protein homolog 5", "Chromodomain", "Chromosome-associated kinesin KIF4A", "Cilia- and flagella-associated protein 20", "Citrate synthase, mitochondrial", "ClC-3/CLCN3 subfamily", "ClC-7/CLCN7 subfamily", "Clathrin heavy chain 1", "Clathrin light chain A", "Cleavage and polyadenylation specificity factor subunit 1", "Cleavage and polyadenylation specificity factor subunit 3", "Cleavage and polyadenylation specificity factor subunit 5", "Cleavage and polyadenylation specificity factor subunit 6", "Cleavage and polyadenylation specificity factor subunit 7", "Cleavage stimulation factor subunit 2", "Cleavage stimulation factor subunit 3", "Cleft lip and palate transmembrane protein 1", "Cleft lip and palate transmembrane protein 1-like protein", "Clustered mitochondria protein homolog", "Coactosin-like protein", "Coatomer subunit alpha", "Coatomer subunit beta", "Coatomer subunit beta'", "Coatomer subunit delta", "Coatomer subunit epsilon", "Coatomer subunit gamma-1", "Coatomer subunit gamma-2", "Coatomer subunit zeta-1", "Cohesin subunit SA-1", "Cohesin subunit SA-2", "Coilin", "Cold-inducible RNA-binding protein", "Collectin-12", "Condensin complex subunit 1", "Condensin-2 complex subunit D3", "Core histone macro-H2A.1", "Core histone macro-H2A.2", "Coronin-1B", "Coronin-1C", "Coronin-7", "Creatine kinase B-type", "Creatine kinase U-type, mitochondrial", "Crooked neck-like protein 1", "Cullin-1", "Cullin-2", "Cullin-4B", "Cullin-5", "Cullin-associated NEDD8-dissociated protein 1", "Cullin-associated NEDD8-dissociated protein 2", "Cyclase", "Cyclin-A2", "Cyclin-dependent kinase 1", "Cyclin-dependent kinase 11b", "Cyclin-dependent kinase 12", "Cyclin-dependent kinase 13", "Cyclin-dependent kinase 2", "Cyclin-dependent kinase 4", "Cyclin-dependent kinase 6", "Cyclin-dependent kinase 9", "Cyclin-dependent-like kinase 5", "Cyclin-g-associated kinase", "Cystathionine gamma-lyase", "Cystatin-B", "Cysteine and histidine-rich domain-containing protein 1", "Cysteine desulfurase, mitochondrial", "Cysteine protease", "Cysteine protease ATG4B", "Cysteine protease inhibitor", "Cysteine--tRNA ligase, cytoplasmic", "Cytochrome b-c1 complex subunit 1, mitochondrial", "Cytochrome b-c1 complex subunit 2, mitochondrial", "Cytochrome b-c1 complex subunit 7", "Cytochrome b-c1 complex subunit 9", "Cytochrome b5 type B", "Cytochrome c oxidase subunit 2", "Cytochrome c oxidase subunit 5A, mitochondrial", "Cytochrome c oxidase subunit 5B, mitochondrial", "Cytochrome c oxidase subunit 7A-related protein, mitochondrial", "Cytochrome c oxidase subunit 7A2, mitochondrial", "Cytochrome c oxidase subunit 7C, mitochondrial", "Cytochrome c oxidase subunit NDUFA4", "Cytochrome c-type heme lyase", "Cytokine", "Cytoplasmic FMR1-interacting protein 1", "Cytoplasmic FMR1-interacting protein 2", "Cytoplasmic aconitate hydratase", "Cytoplasmic dynein 1 heavy chain 1", "Cytoplasmic dynein 1 intermediate chain 2", "Cytoplasmic dynein 1 light intermediate chain 1", "Cytoplasmic dynein 1 light intermediate chain 2", "Cytoplasmic dynein 2 heavy chain 1", "Cytoskeleton-associated protein 5", "Cytosol aminopeptidase", "Cytosolic 5'-nucleotidase 3A", "Cytosolic acyl coenzyme A thioester hydrolase", "Cytosolic non-specific dipeptidase", "Cytosolic purine 5'-nucleotidase", "D-3-phosphoglycerate dehydrogenase", "D-dopachrome decarboxylase", "DDB1- and CUL4-associated factor 13", "DMPK family", "DNA (cytosine-5)-methyltransferase 1", "DNA binding protein", "DNA dC->dU-editing enzyme APOBEC-3C", "DNA damage-binding protein 1", "DNA glycosylase", "DNA helicase", "DNA ligase", "DNA ligase 1", "DNA ligase 3", "DNA methyltransferase", "DNA mismatch repair protein Msh2", "DNA mismatch repair protein Msh3", "DNA mismatch repair protein Msh6", "DNA polymerase alpha subunit B", "DNA polymerase delta subunit 2", "DNA polymerase epsilon subunit 4", "DNA polymerase processivity factor", "DNA primase small subunit", "DNA replication licensing factor MCM2", "DNA replication licensing factor MCM3", "DNA replication licensing factor MCM4", "DNA replication licensing factor MCM5", "DNA replication licensing factor MCM6", "DNA replication licensing factor MCM7", "DNA topoisomerase", "DNA topoisomerase 1", "DNA topoisomerase 3-alpha", "DNA-3-methyladenine glycosylase", "DNA-binding protein SATB2", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "DNA-directed RNA polymerase I subunit RPA1", "DNA-directed RNA polymerase I subunit RPA2", "DNA-directed RNA polymerase II subunit RPB1", "DNA-directed RNA polymerase II subunit RPB2", "DNA-directed RNA polymerase II subunit RPB3", "DNA-directed RNA polymerase II subunit RPB4", "DNA-directed RNA polymerase II subunit RPB7", "DNA-directed RNA polymerase III subunit RPC1", "DNA-directed RNA polymerase III subunit RPC3", "DNA-directed RNA polymerase III subunit RPC6", "DNA-directed RNA polymerase, mitochondrial", "DNA-directed RNA polymerases I and III subunit RPAC1", "DNA-directed RNA polymerases I, II, and III subunit RPABC1", "DNA-directed RNA polymerases I, II, and III subunit RPABC5", "DNAPK subfamily", "DYRK family", "Damaged DNA-binding protein", "Deacetylase", "Deaminase", "Death-inducer obliterator 1", "Decarboxylase", "Dedicator of cytokinesis protein 7", "Dehydratase", "Dehydrogenase", "Delta(24)-sterol reductase", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial", "Delta-1-pyrroline-5-carboxylate synthase", "Density-regulated protein", "Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial", "Derlin-1", "Derlin-2", "Desmocollin-2", "Desmocollin-3", "Desmoglein-2", "Desmoplakin", "Digestive organ expansion factor homolog", "Dihydrofolate reductase", "Dihydrolipoyl dehydrogenase, mitochondrial", "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial", "Dihydropyrimidinase-related protein 2", "Dihydropyrimidinase-related protein 3", "Dihydropyrimidinase-related protein 5", "Dipeptidyl peptidase 1", "Dipeptidyl peptidase 3", "Diphthine methyl ester synthase", "Disintegrin and metalloproteinase domain-containing protein 9", "Disks large homolog 1", "Dna-dependent protein kinase catalytic subunit", "Dolichol-phosphate mannosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B", "Dolichyldiphosphatase 1", "Double-stranded RNA-specific adenosine deaminase", "Drebrin", "Drebrin-like protein", "Dual specificity mitogen-activated protein kinase kinase 1", "Dual specificity mitogen-activated protein kinase kinase 4", "Dual specificity protein kinase ttk", "Dynactin subunit 1", "Dynactin subunit 2", "Dynamin-1-like protein", "Dynamin-2", "Dynamin-like 120 kDa protein, mitochondrial", "Dynein light chain 1, cytoplasmic", "Dynein light chain 2, cytoplasmic", "Dystonin", "E3 SUMO-protein ligase RanBP2", "E3 ubiquitin-protein ligase ARIH1", "E3 ubiquitin-protein ligase CBL", "E3 ubiquitin-protein ligase HUWE1", "E3 ubiquitin-protein ligase Itchy homolog", "E3 ubiquitin-protein ligase MARCH5", "E3 ubiquitin-protein ligase NEDD4", "E3 ubiquitin-protein ligase NEDD4-like", "E3 ubiquitin-protein ligase RBBP6", "E3 ubiquitin-protein ligase RNF14", "E3 ubiquitin-protein ligase ZNF598", "E3 ubiquitin-protein ligase listerin", "EF-hand domain-containing protein D1", "EGFR family", "EH domain-containing protein 1", "EH domain-containing protein 4", "ELKS/Rab6-interacting/CAST family member 1", "ELMO domain-containing protein 2", "ER lumen protein-retaining receptor 1", "ER lumen protein-retaining receptor 3", "ER membrane protein complex subunit 2", "ERK subfamily", "ERO1-like protein alpha", "Early endosome antigen 1", "Ectonucleotide pyrophosphatase/phosphodiesterase family member 1", "Electron transfer flavoprotein subunit alpha, mitochondrial", "Electron transfer flavoprotein subunit beta", "Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial", "Elongation factor 1-alpha 2", "Elongation factor 1-beta", "Elongation factor 1-delta", "Elongation factor 2", "Elongation factor Ts, mitochondrial", "Elongation factor Tu, mitochondrial", "Elongation factor-like GTPase 1", "Elongator complex protein 1", "Elongator complex protein 3", "Elongin-B", "Elongin-C", "Endodeoxyribonuclease", "Endonuclease III-like protein 1", "Endoplasmic reticulum aminopeptidase 1", "Endoplasmic reticulum aminopeptidase 2", "Endoplasmic reticulum metallopeptidase 1", "Endoplasmic reticulum protein SC65", "Endoplasmic reticulum resident protein 29", "Endoplasmin", "Endoribonuclease", "Endoribonuclease Dicer", "Endothelin-converting enzyme 1", "Engulfment and cell motility protein 2", "Enhancer of mRNA-decapping protein 4", "Enhancer of rudimentary homolog", "Enoyl-CoA delta isomerase 1, mitochondrial", "Enoyl-CoA delta isomerase 2, mitochondrial", "Enoyl-CoA hydratase, mitochondrial", "Enzyme", "Enzyme modulator", "Eph family", "Ephrin type-a receptor 7", "Epidermal growth factor receptor", "Epidermal growth factor receptor substrate 15", "Epidermal growth factor receptor substrate 15-like 1", "Epigenetic regulator", "Epimerase/racemase", "Epiplakin", "Equilibrative nucleoside transporter 1", "Eraser", "Erythrocyte band 7 integral membrane protein", "Esterase", "Ethanolamine kinase 1", "Ethylmalonyl-CoA decarboxylase", "Eukaryotic peptide chain release factor GTP-binding subunit ERF3A", "Eukaryotic peptide chain release factor subunit 1", "Eukaryotic translation initiation factor 2 subunit 1", "Eukaryotic translation initiation factor 2 subunit 2", "Eukaryotic translation initiation factor 2A", "Eukaryotic translation initiation factor 2D", "Eukaryotic translation initiation factor 3 subunit A", "Eukaryotic translation initiation factor 3 subunit B", "Eukaryotic translation initiation factor 3 subunit D", "Eukaryotic translation initiation factor 3 subunit E", "Eukaryotic translation initiation factor 3 subunit F", "Eukaryotic translation initiation factor 3 subunit H", "Eukaryotic translation initiation factor 3 subunit I", "Eukaryotic translation initiation factor 3 subunit J", "Eukaryotic translation initiation factor 3 subunit L", "Eukaryotic translation initiation factor 4 gamma 1", "Eukaryotic translation initiation factor 4 gamma 2", "Eukaryotic translation initiation factor 4 gamma 3", "Eukaryotic translation initiation factor 4B", "Eukaryotic translation initiation factor 4E", "Eukaryotic translation initiation factor 4H", "Eukaryotic translation initiation factor 5", "Eukaryotic translation initiation factor 5A-1", "Eukaryotic translation initiation factor 5B", "Eukaryotic translation initiation factor 6", "Exocyst complex component 3", "Exocyst complex component 4", "Exocyst complex component 5", "Exocyst complex component 6", "Exocyst complex component 7", "Exodeoxyribonuclease", "Exonuclease 1", "Exoribonuclease", "Exosome complex component CSL4", "Exosome complex component MTR3", "Exosome complex component RRP4", "Exosome complex component RRP40", "Exosome complex component RRP41", "Exosome complex component RRP42", "Exosome complex component RRP45", "Exosome complex component RRP46", "Exosome complex exonuclease RRP44", "Exportin-1", "Exportin-2", "Exportin-4", "Exportin-5", "Exportin-7", "Exportin-T", "Extracellular matrix glycoprotein", "Extracellular matrix structural protein", "Extracellular structure", "Ezrin", "F-actin-capping protein subunit alpha-1", "F-actin-capping protein subunit alpha-2", "F-actin-capping protein subunit beta", "F-type ATPase", "F-type and V-type ATPases", "FACT complex subunit SPT16", "FAD-dependent oxidoreductase domain-containing protein 1", "FRAP subfamily", "FRAY subfamily", "Far upstream element-binding protein 1", "Far upstream element-binding protein 2", "Far upstream element-binding protein 3", "Farnesyl pyrophosphate synthase", "Fascin", "Fatty acid synthase", "Ferrochelatase, mitochondrial", "Flap endonuclease 1", "Folate transporter 1", "Follistatin-related protein 1", "Fragile X mental retardation syndrome-related protein 1", "Fragile X mental retardation syndrome-related protein 2", "Fumarate hydratase, mitochondrial", "G patch domain-containing protein 4", "G-patch domain and KOW motifs-containing protein", "G-protein", "G-protein coupled receptor", "G-protein modulator", "G-rich sequence factor 1", "G2/mitotic-specific cyclin-B1", "G2/mitotic-specific cyclin-B2", "GC-rich sequence DNA-binding factor 2", "GDP-L-fucose synthase", "GDP-fucose protein O-fucosyltransferase 2", "GMP synthase [glutamine-hydrolyzing]", "GPI-anchor transamidase", "GSK family", "GSK subfamily", "GTP-binding nuclear protein Ran", "GTP-binding protein 1", "GTP-binding protein Rheb", "GTPase Era, mitochondrial", "GTPase-activating protein and VPS9 domain-containing protein 1", "Galactokinase", "Galactosidase", "Galectin-3", "Gamma-adducin", "Gamma-aminobutyric acid receptor-associated protein-like 2", "Gamma-enolase", "Gamma-glutamyl hydrolase", "Gamma-taxilin", "Gamma-tubulin complex component 2", "Gamma-tubulin complex component 3", "Ganglioside GM2 activator", "General transcription factor 3C polypeptide 3", "General transcription factor 3C polypeptide 5", "General transcription factor IIF subunit 1", "General transcription factor IIF subunit 2", "General vesicular transport factor p115", "Geranylgeranyl transferase type-2 subunit alpha", "Glia maturation factor beta", "Glucosamine-6-phosphate isomerase 1", "Glucose-6-phosphate 1-dehydrogenase", "Glucose-6-phosphate isomerase", "Glucosidase", "Glucosidase 2 subunit beta", "Glutamate dehydrogenase 1, mitochondrial", "Glutaminase kidney isoform, mitochondrial", "Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1", "Glutamine--tRNA ligase", "Glutamine-rich protein 1", "Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial", "Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial", "Glutaredoxin-3", "Glutaredoxin-related protein 5, mitochondrial", "Glutathione reductase, mitochondrial", "Glutathione synthetase", "Glyceraldehyde-3-phosphate dehydrogenase", "Glycerol-3-phosphate acyltransferase 4", "Glycerol-3-phosphate dehydrogenase, mitochondrial", "Glycerol-3-phosphate phosphatase", "Glycine dehydrogenase (decarboxylating), mitochondrial", "Glycine--tRNA ligase", "Glycogen debranching enzyme", "Glycogen phosphorylase, brain form", "Glycogen phosphorylase, liver form", "Glycogen synthase kinase-3 beta", "Glycogenin-1", "Glycosidase", "Glycosylase", "Glycosyltransferase", "Glycylpeptide N-tetradecanoyltransferase 1", "Glyoxylate reductase/hydroxypyruvate reductase", "Golgi SNAP receptor complex member 1", "Golgi pH regulator family", "Golgi ph regulator b", "Golgin subfamily A member 2", "Group XV phospholipase A2", "Growth factor", "GrpE protein homolog 1, mitochondrial", "Gtp:amp phosphotransferase ak3, mitochondrial", "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12", "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5", "Guanine nucleotide-binding protein G(i) subunit alpha-2", "Guanine nucleotide-binding protein G(k) subunit alpha", "Guanine nucleotide-binding protein subunit alpha-13", "Guanyl-nucleotide exchange factor", "H(+)/Cl(-) exchange transporter 3", "H(+)/Cl(-) exchange transporter 7", "H/ACA ribonucleoprotein complex subunit 1", "H/ACA ribonucleoprotein complex subunit 2", "HBS1-like protein", "HDAC class I", "HDAC class III", "HEAT repeat-containing protein 1", "HEAT repeat-containing protein 6", "HIV Tat-specific factor 1", "Haloacid dehalogenase-like hydrolase domain-containing 5", "Haloacid dehalogenase-like hydrolase domain-containing protein 2", "Heat shock protein 75 kDa, mitochondrial", "Heat shock protein HSP 90-alpha", "Heat shock protein HSP 90-beta", "Helicase", "Helix-turn-helix transcription factor", "Heparanase", "Hepatoma-derived growth factor", "Hepatoma-derived growth factor-related protein 2", "Heterogeneous nuclear ribonucleoprotein F", "Heterogeneous nuclear ribonucleoprotein H", "Heterogeneous nuclear ribonucleoprotein H2", "Heterogeneous nuclear ribonucleoprotein H3", "Heterogeneous nuclear ribonucleoprotein K", "Heterogeneous nuclear ribonucleoprotein M", "Heterogeneous nuclear ribonucleoprotein Q", "Heterogeneous nuclear ribonucleoprotein R", "Heterotrimeric G-protein", "Hexokinase family", "Hexokinase-1", "Hexokinase-2", "High affinity cationic amino acid transporter 1", "High mobility group nucleosome-binding domain-containing protein 3", "High mobility group protein B1", "High mobility group protein B2", "High mobility group protein B3", "High mobility group protein HMG-I/HMG-Y", "Histidine triad nucleotide-binding protein 2, mitochondrial", "Histidine triad nucleotide-binding protein 3", "Histone", "Histone H1.0", "Histone H1.2", "Histone H1.3", "Histone H1.4", "Histone H1x", "Histone H2AX", "Histone H4", "Histone acetyltransferase KAT7", "Histone acetyltransferase type B catalytic subunit", "Histone deacetylase", "Histone deacetylase 1", "Histone deacetylase 2", "Histone deacetylase complex subunit SAP18", "Histone-arginine methyltransferase CARM1", "Histone-lysine N-methyltransferase EHMT2", "Histone-lysine N-methyltransferase EZH2", "Histone-lysine N-methyltransferase NSD2", "Histone-lysine N-methyltransferase SETD7", "Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific", "Hormone", "Hsp90 co-chaperone Cdc37", "Hsp90 family chaperone", "Hydrolase", "Hydroxylase", "Hydroxymethylglutaryl-CoA lyase, mitochondrial", "Hypoxanthine-guanine phosphoribosyltransferase", "IKK family", "ILK subfamily", "Immune response", "Immunoglobulin fold transcription factor", "Immunoglobulin superfamily cell adhesion molecule", "Immunoglobulin-binding protein 1", "Importin subunit alpha-1", "Importin subunit alpha-3", "Importin subunit alpha-4", "Importin subunit alpha-5", "Importin subunit alpha-7", "Importin subunit beta-1", "Importin-4", "Importin-5", "Importin-7", "Importin-8", "Importin-9", "Inactive tyrosine-protein kinase 7", "Induced myeloid leukemia cell differentiation protein Mcl-1", "Inhibitor of nuclear factor kappa-b kinase subunit alpha", "Inorganic pyrophosphatase", "Inorganic pyrophosphatase 2, mitochondrial", "Inosine triphosphate pyrophosphatase", "Inosine-5'-monophosphate dehydrogenase 2", "Inositol monophosphatase 3", "Inositol polyphosphate 5-phosphatase OCRL-1", "Insulin-degrading enzyme", "Insulin-like growth factor 2 mRNA-binding protein 1", "Insulin-like growth factor 2 mRNA-binding protein 2", "Insulin-like growth factor 2 mRNA-binding protein 3", "Integrator complex subunit 11", "Integrin beta-1", "Integrin-linked kinase-associated serine/threonine phosphatase 2C", "Integrin-linked protein kinase", "Interferon-induced, double-stranded rna-activated protein kinase", "Interferon-inducible double-stranded rna-dependent protein kinase activator a", "Interleukin enhancer-binding factor 3", "Intermediate filament", "Intermediate filament binding protein", "Intracellular calcium-sensing protein", "Intracellular chloride channel (clic) family", "Intracellular chloride channel (icc) family", "Ion channel", "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial", "Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial", "Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial", "Isoleucine--tRNA ligase, cytoplasmic", "Isoleucine--tRNA ligase, mitochondrial", "Isomerase", "Isopentenyl-diphosphate Delta-isomerase 1", "Isovaleryl-CoA dehydrogenase, mitochondrial", "Jumonji domain-containing", "KH domain-containing, RNA-binding, signal transduction-associated protein 1", "KH domain-containing, RNA-binding, signal transduction-associated protein 3", "KRAB box transcription factor", "KRR1 small subunit processome component homolog", "Ketosamine-3-kinase", "Kinase", "Kinase activator", "Kinase inhibitor", "Kinase modulator", "Kinesin-1 heavy chain", "Kinesin-like protein KIF11", "Kinesin-like protein KIF14", "Kinesin-like protein KIF18B", "Kinesin-like protein KIF1A", "Kinesin-like protein KIF1B", "Kinesin-like protein KIF20A", "Kinesin-like protein KIF20B", "Kinesin-like protein KIF22", "Kinesin-like protein KIF23", "Kinesin-like protein KIF2A", "Kinesin-like protein KIF2C", "Kinesin-like protein KIF3A", "Kinesin-like protein KIF7", "Kinesin-like protein KIFC1", "Kinetochore protein Nuf2", "Kynurenine--oxoglutarate transaminase 3", "L-2-hydroxyglutarate dehydrogenase, mitochondrial", "L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase", "L-lactate dehydrogenase A chain", "L-lactate dehydrogenase B chain", "LIM domain and actin-binding protein 1", "LU7TM family", "La-related protein 1", "La-related protein 4", "La-related protein 4B", "La-related protein 7", "Lambda repressor-like transcription factor", "Lamin-B receptor", "Lamina-associated polypeptide 2, isoform alpha", "Laminin subunit beta-1", "Laminin subunit gamma-1", "Lanosterol 14-alpha demethylase", "Large proline-rich protein BAG6", "Lathosterol oxidase", "Legumain", "Lethal(2) giant larvae protein homolog 1", "Leucine-rich repeat and WD repeat-containing protein 1", "Leucine-rich repeat flightless-interacting protein 2", "Leucine-rich repeat-containing protein 47", "Leucyl-cystinyl aminopeptidase", "Ligase", "Lipase", "Lipid kinase", "Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial", "Lon protease homolog, mitochondrial", "Long-chain fatty acid transport protein 4", "Long-chain-fatty-acid--CoA ligase 1", "Long-chain-fatty-acid--CoA ligase 3", "Long-chain-fatty-acid--CoA ligase 4", "Long-chain-fatty-acid--CoA ligase 6", "Lupus La protein", "Lyase", "Lymphokine-activated killer t-cell-originated protein kinase", "Lysine demethylase", "Lysine--tRNA ligase", "Lysine-specific demethylase", "Lysine-specific demethylase 3B", "Lysine-specific histone demethylase 1A", "Lysine-specific histone demethylase 1B", "Lysophosphatidic acid phosphatase type 6", "Lysophosphatidylcholine acyltransferase 1", "Lysophospholipid acyltransferase 7", "Lysosomal Pro-X carboxypeptidase", "Lysosomal acid lipase/cholesteryl ester hydrolase", "Lysosomal acid phosphatase", "Lysosomal alpha-glucosidase", "Lysosomal protective protein", "Lysosomal thioesterase PPT2", "Lysosome membrane protein 2", "Lysosome-associated membrane glycoprotein 1", "Lysosome-associated membrane glycoprotein 2", "M-phase phosphoprotein 8", "MAGUK p55 subfamily member 2", "MAGUK p55 subfamily member 5", "MAGUK p55 subfamily member 6", "MAGUK p55 subfamily member 7", "MAP7 domain-containing protein 1", "MAPK family", "MARK subfamily", "MCU family", "MLK family", "MMS19 nucleotide excision repair protein homolog", "MOB-like protein phocein", "MST subfamily", "Magnesium transporter protein 1", "Major facilitator superfamily domain-containing protein 3", "Major histocompatibility complex antigen", "Malate dehydrogenase, cytoplasmic", "Malate dehydrogenase, mitochondrial", "Malignant T-cell-amplified sequence 1", "Mannose-6-phosphate isomerase", "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA", "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB", "Map/microtubule affinity-regulating kinase 3", "Mediator of RNA polymerase II transcription subunit 12", "Mediator of RNA polymerase II transcription subunit 14", "Mediator of RNA polymerase II transcription subunit 21", "Mediator of RNA polymerase II transcription subunit 25", "Medium-chain specific acyl-CoA dehydrogenase, mitochondrial", "Melanoma inhibitory activity protein 2", "Melanoma-associated antigen D1", "Melanoma-associated antigen D2", "Membrane trafficking regulatory protein", "Membrane-associated progesterone receptor component 1", "Membrane-associated progesterone receptor component 2", "Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase", "Metalloprotease", "Metastasis-associated protein MTA1", "Metastasis-associated protein MTA2", "Methionine aminopeptidase 1", "Methyl-CpG-binding domain", "Methyl-CpG-binding protein 2", "Methyl-lysine/arginine binding protein", "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial", "Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial", "Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial", "Methylmalonyl-CoA mutase, mitochondrial", "Methylosome subunit pICln", "Methylsterol monooxygenase 1", "Methyltransferase", "Microfibrillar-associated protein 1", "Microsomal glutathione S-transferase 2", "Microsomal glutathione S-transferase 3", "Microtubule binding motor protein", "Microtubule family cytoskeletal protein", "Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5", "Microtubule-associated protein 1A", "Microtubule-associated protein 1B", "Microtubule-associated protein 1S", "Microtubule-associated protein RP/EB family member 1", "Microtubule-associated protein RP/EB family member 2", "Minor histocompatibility antigen H13", "Miscellaneous SLC25 mitochondrial transporters", "Mitochondrial 2-oxodicarboxylate carrier", "Mitochondrial 2-oxoglutarate/malate carrier protein", "Mitochondrial Rho GTPase 1", "Mitochondrial Rho GTPase 2", "Mitochondrial amino acid transporter subfamily", "Mitochondrial cardiolipin hydrolase", "Mitochondrial carnitine/acylcarnitine carrier protein", "Mitochondrial carrier homolog 1", "Mitochondrial carrier homolog 2", "Mitochondrial di- and tri-carboxylic acid transporter subfamily", "Mitochondrial dicarboxylate carrier", "Mitochondrial folate transporter/carrier", "Mitochondrial glutamate carrier 1", "Mitochondrial import receptor subunit TOM20 homolog", "Mitochondrial import receptor subunit TOM40 homolog", "Mitochondrial inner membrane protein OXA1L", "Mitochondrial intermediate peptidase", "Mitochondrial nucleotide transporter subfamily", "Mitochondrial ornithine transporter 1", "Mitochondrial phosphate transporters", "Mitochondrial proton/calcium exchanger protein", "Mitochondrial pyruvate carrier 2", "Mitochondrial-processing peptidase subunit alpha", "Mitochondrial-processing peptidase subunit beta", "Mitofusin-1", "Mitogen-activated protein kinase 1", "Mitogen-activated protein kinase 14", "Mitogen-activated protein kinase 3", "Mitotic checkpoint protein BUB3", "Mitotic checkpoint serine/threonine-protein kinase bub1 beta", "Moesin", "Molybdate-anion transporter", "Monoacylglycerol lipase ABHD12", "Monoacylglycerol lipase ABHD6", "Monocarboxylate transporter 1", "Monofunctional C1-tetrahydrofolate synthase, mitochondrial", "Mortality factor 4-like protein 1", "Mortality factor 4-like protein 2", "Mpv17-like protein 2", "Multidrug resistance protein 1", "Multidrug resistance-associated protein 1", "Multifunctional protein ADE2", "Mutase", "Myb-binding protein 1A", "Myelin expression factor 2", "Myosin light polypeptide 6", "Myosin phosphatase Rho-interacting protein", "Myotubularin", "Myotubularin-related protein 2", "Myotubularin-related protein 6", "N-acetylgalactosaminyltransferase 7", "N-acetylglucosamine-6-sulfatase", "N-acylneuraminate cytidylyltransferase", "N-alpha-acetyltransferase 10", "N-alpha-acetyltransferase 15, NatA auxiliary subunit", "N-alpha-acetyltransferase 50", "N-terminal Xaa-Pro-Lys N-methyltransferase 1", "NAD kinase 2, mitochondrial", "NAD(P) transhydrogenase, mitochondrial", "NAD-dependent malic enzyme, mitochondrial", "NAD-dependent protein deacetylase sirtuin-1", "NAD-dependent protein deacetylase sirtuin-2", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9", "NADH dehydrogenase [ubiquinone] 1 subunit C2", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial", "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial", "NADH-ubiquinone oxidoreductase chain 1", "NADP-dependent malic enzyme", "NADPH:adrenodoxin oxidoreductase, mitochondrial", "NAK family", "NEDD8-activating enzyme E1 regulatory subunit", "NEK family", "NF-kappa-B-repressing factor", "NHP2-like protein 1", "NLR family member X1", "NRBP family", "NSFL1 cofactor p47", "Na+/K+-ATPases", "Nardilysin", "Neuferricin", "Neurolysin, mitochondrial", "Neuropathy target esterase", "Neutral alpha-glucosidase AB", "Neutral amino acid transporter B(0)", "Neutral amino acid transporter subfamily", "Nibrin", "Nicotinamide phosphoribosyltransferase", "Nipped-B-like protein", "Nischarin", "Non-POU domain-containing octamer-binding protein", "Non-histone chromosomal protein HMG-14", "Non-motor actin binding protein", "Non-motor microtubule binding protein", "Non-protein kinase", "Non-structural maintenance of chromosomes element 3 homolog", "Nuclear RNA export factor 1", "Nuclear cap-binding protein subunit 1", "Nuclear factor related to kappa-B-binding protein", "Nuclear migration protein nudC", "Nuclear nucleic acid-binding protein C1D", "Nuclear pore complex protein Nup107", "Nuclear pore complex protein Nup153", "Nuclear pore complex protein Nup160", "Nuclear pore complex protein Nup214", "Nuclear pore complex protein Nup85", "Nuclear pore complex protein Nup88", "Nuclear pore complex protein Nup93", "Nuclear pore complex protein Nup98-Nup96", "Nuclear pore glycoprotein p62", "Nuclear pore membrane glycoprotein 210", "Nuclear receptor", "Nuclear receptor coactivator 5", "Nuclear receptor-binding protein", "Nuclease", "Nucleic acid binding", "Nucleobindin-1", "Nucleobindin-2", "Nucleolar MIF4G domain-containing protein 1", "Nucleolar complex protein 4 homolog", "Nucleolar protein 14", "Nucleolar protein 56", "Nucleolar protein 58", "Nucleolar protein 6", "Nucleolar protein 9", "Nucleolin", "Nucleophosmin", "Nucleoporin Nup37", "Nucleoporin SEH1", "Nucleoporin p54", "Nucleoside diphosphate kinase 3", "Nucleoside diphosphate kinase A", "Nucleoside diphosphate kinase B", "Nucleoside kinase", "Nucleosome assembly protein 1-like 1", "Nucleosome assembly protein 1-like 4", "Nucleotide kinase", "Nucleotide phosphatase", "Nucleotidyltransferase", "NudC domain-containing protein 2", "OCIA domain-containing protein 1", "OTU domain-containing protein 7B", "Obg-like ATPase 1", "Occludin", "Origin recognition complex subunit 2", "Origin recognition complex subunit 3", "Origin recognition complex subunit 5", "Ornithine aminotransferase, mitochondrial", "Other 7TM proteins", "Other group", "Other small molecule kinase", "Oxidase", "Oxidoreductase", "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial", "Oxygenase", "P-type ATPases", "P38 subfamily", "P53-like transcription factor", "PAKA subfamily", "PAKB subfamily", "PAX3- and PAX7-binding protein 1", "PC4 and SFRS1-interacting protein", "PDHK family", "PDZ and LIM domain protein 1", "PDZ and LIM domain protein 5", "PDZ domain-containing protein 11", "PEK family", "PH-interacting protein", "PHD finger protein 10", "PHD finger protein 14", "PHD finger protein 3", "PHD finger protein 6", "PI3/PI4 kinase family", "PIKK family", "PIN2/TERF1-interacting telomerase inhibitor 1", "PITSLRE subfamily", "PKA family", "PKC delta subfamily", "PKC family", "PKN family", "PLK family", "PMS1 protein homolog 1", "Paired amphipathic helix protein Sin3a", "Paired amphipathic helix protein Sin3b", "Palmitoyl-protein thioesterase 1", "Pantothenate kinase 4", "Paraspeckle component 1", "Pentatricopeptide repeat-containing protein 1, mitochondrial", "Peptidyl-prolyl cis-trans isomerase FKBP1A", "Peptidyl-prolyl cis-trans isomerase FKBP4", "Peptidyl-prolyl cis-trans isomerase FKBP5", "Peptidyl-prolyl cis-trans isomerase-like 1", "Perilipin-3", "Periodic tryptophan protein 1 homolog", "Peripheral plasma membrane protein cask", "Peroxidase", "Peroxiredoxin-2", "Peroxiredoxin-4", "Peroxiredoxin-6", "Peroxisomal NADH pyrophosphatase NUDT12", "Peroxisomal acyl-coenzyme A oxidase 1", "Peroxisomal acyl-coenzyme A oxidase 3", "Peroxisomal bifunctional enzyme", "Peroxisomal biogenesis factor 19", "Peroxisomal membrane protein 2", "Peroxisomal membrane protein PEX14", "Peroxisomal membrane protein PMP34", "Peroxisomal targeting signal 1 receptor", "Peroxisomal trans-2-enoyl-CoA reductase", "Pescadillo homolog", "Phenylalanine--tRNA ligase beta subunit", "Phosphatase", "Phosphatase activator", "Phosphatase inhibitor", "Phosphatase modulator", "Phosphate carrier protein, mitochondrial", "Phosphatidylethanolamine-binding protein 1", "Phosphatidylinositol 4-kinase alpha", "Phosphatidylinositol 4-kinase beta", "Phosphatidylinositol 4-kinase type 2-alpha", "Phosphatidylinositol 4-phosphate 3-kinase c2 domain-containing subunit alpha", "Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma", "Phosphatidylinositol transfer protein beta isoform", "Phosphatidylinositol-binding clathrin assembly protein", "Phosphatidylserine synthase 1", "Phosphatidylserine synthase 2", "Phosphodiesterase", "Phosphoenolpyruvate carboxykinase [GTP] family", "Phosphoenolpyruvate carboxykinase [gtp], mitochondrial", "Phosphofructokinase type A (PFKA) family", "Phosphoglycerate kinase 1", "Phosphoglycerate kinase family", "Phosphoinositide 3-kinase (PI3K) family", "Phosphoinositide 3-kinase regulatory subunit 4", "Phospholipase", "Phospholipase A-2-activating protein", "Phospholipid-transporting ATPase IG", "Phospholipid-transporting ATPases", "Phosphoribosyl pyrophosphate synthase-associated protein 1", "Phosphoribosyl pyrophosphate synthase-associated protein 2", "Phosphorylase", "Phosphorylated adapter RNA export protein", "Pirin", "Plakophilin-2", "Plasma membrane calcium-transporting ATPase 1", "Plasminogen activator inhibitor 1 RNA-binding protein", "Plastin-1", "Plastin-3", "Plectin", "Pogo transposable element with ZNF domain", "Poly(A) RNA polymerase, mitochondrial", "Poly(A) polymerase alpha", "Poly(A)-specific ribonuclease PARN", "Poly(ADP-ribose) glycohydrolase", "Poly(rC)-binding protein 1", "Poly(rC)-binding protein 2", "Polyadenylate-binding protein-interacting protein 1", "Polycomb protein SUZ12", "Polyhomeotic-like protein 2", "Polymerase", "Polymerase delta-interacting protein 3", "Polypeptide N-acetylgalactosaminyltransferase 1", "Polypeptide N-acetylgalactosaminyltransferase 2", "Polyribonucleotide nucleotidyltransferase 1, mitochondrial", "Porphobilinogen deaminase", "Pre-mRNA-processing factor 17", "Pre-mRNA-processing factor 6", "Pre-mRNA-processing-splicing factor 8", "Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15", "Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16", "Pre-mRNA-splicing factor CWC22 homolog", "Pre-mRNA-splicing factor RBM22", "Pre-mRNA-splicing factor SPF27", "Pre-mRNA-splicing factor SYF1", "Prefoldin subunit 2", "Prefoldin subunit 3", "Prefoldin subunit 5", "Presequence protease, mitochondrial", "Primase", "Probable 18S rRNA (guanine-N(7))-methyltransferase", "Probable ATP-dependent RNA helicase DHX37", "Probable ATP-dependent RNA helicase DHX40", "Probable E3 ubiquitin-protein ligase makorin-2", "Probable RNA-binding protein 19", "Probable U3 small nucleolar RNA-associated protein 11", "Probable cysteine--tRNA ligase, mitochondrial", "Probable global transcription activator SNF2L1", "Probable glutamate--tRNA ligase, mitochondrial", "Probable helicase with zinc finger domain", "Probable leucine--tRNA ligase, mitochondrial", "Probable methyltransferase-like protein 15", "Probable serine carboxypeptidase CPVL", "Probable tRNA N6-adenosine threonylcarbamoyltransferase", "Probable tRNA pseudouridine synthase 1", "Procollagen galactosyltransferase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2", "Programmed cell death 6-interacting protein", "Programmed cell death protein 4", "Programmed cell death protein 5", "Prolactin regulatory element-binding protein", "Proliferating cell nuclear antigen", "Prolyl 3-hydroxylase 1", "Prolyl 3-hydroxylase 3", "Prolyl endopeptidase", "Propionyl-CoA carboxylase alpha chain, mitochondrial", "Propionyl-CoA carboxylase beta chain, mitochondrial", "Prostaglandin E synthase 2", "Prostaglandin E synthase 3", "Prostaglandin reductase 1", "Prostaglandin reductase 2", "Prostaglandin reductase 3", "Protease", "Protease inhibitor", "Proteasome inhibitor PI31 subunit", "Protein AATF", "Protein BUD31 homolog", "Protein CMSS1", "Protein DDI1 homolog 2", "Protein ERGIC-53", "Protein FAM177A1", "Protein HIRA", "Protein Hook homolog 2", "Protein LSM14 homolog B", "Protein NDRG3", "Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2", "Protein PRRC2A", "Protein PRRC2B", "Protein PRRC2C", "Protein RRP5 homolog", "Protein Red", "Protein S100-A10", "Protein S100-A11", "Protein S100-A13", "Protein SCO1 homolog, mitochondrial", "Protein SCO2 homolog, mitochondrial", "Protein SET", "Protein Wiz", "Protein XRP2", "Protein arginine N-methyltransferase 1", "Protein arginine N-methyltransferase 3", "Protein arginine N-methyltransferase 5", "Protein arginine methyltransferase", "Protein gpr107", "Protein kinase", "Protein kinase C and casein kinase substrate in neurons protein 2", "Protein kinase c delta type", "Protein methyltransferase", "Protein phosphatase", "Protein phosphatase 1F", "Protein phosphatase 1G", "Protein phosphatase methylesterase 1", "Protein polybromo-1", "Protein quaking", "Protein regulator of cytokinesis 1", "Protein spinster homolog 1", "Protein strawberry notch homolog 1", "Protein transport protein Sec23A", "Protein transport protein Sec23B", "Protein transport protein Sec24A", "Protein transport protein Sec24B", "Protein transport protein Sec24C", "Protein transport protein Sec31A", "Protein transport protein Sec61 subunit alpha isoform 1", "Protein tweety homolog 3", "Protein unc-119 homolog B", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase", "Protein/nucleic acid deglycase DJ-1", "Proto-oncogene c-Rel", "Pseudouridine-5'-phosphatase", "Pterin-4-alpha-carbinolamine dehydratase", "Pumilio homolog 1", "Purine nucleoside phosphorylase", "Puromycin-sensitive aminopeptidase", "Putative ATP-dependent RNA helicase DHX57", "Putative oxidoreductase GLYR1", "Putative phospholipase B-like 2", "Pyridoxal kinase", "Pyridoxine kinase family", "Pyridoxine-5'-phosphate oxidase", "Pyrophosphatase", "Pyruvate carboxylase, mitochondrial", "Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial", "Pyruvate kinase pkm", "RAD53 family", "RILP-like protein 1", "RNA 3'-terminal phosphate cyclase", "RNA 3'-terminal phosphate cyclase-like protein", "RNA binding motif protein, X-linked-like-1", "RNA binding protein", "RNA binding protein fox-1 homolog 2", "RNA helicase", "RNA-binding motif protein, X chromosome", "RNA-binding protein 12", "RNA-binding protein 12B", "RNA-binding protein 14", "RNA-binding protein 26", "RNA-binding protein 27", "RNA-binding protein 3", "RNA-binding protein 4", "RNA-binding protein EWS", "RNA-binding protein FUS", "RNA-binding protein Nova-1", "RNA-binding protein Nova-2", "RNA-binding protein with serine-rich domain 1", "ROCK subfamily", "RSK family", "RSK subfamily", "Rab GDP dissociation inhibitor alpha", "Rab GDP dissociation inhibitor beta", "Rab GTPase-activating protein 1", "Rab3 GTPase-activating protein non-catalytic subunit", "Rac GTPase-activating protein 1", "Rac-alpha serine/threonine-protein kinase", "Rac-beta serine/threonine-protein kinase", "Radixin", "RalBP1-associated Eps domain-containing protein 1", "Ran GTPase-activating protein 1", "Ran-binding protein 3", "Ran-binding protein 6", "Ran-binding protein 9", "Ran-specific GTPase-activating protein", "Rap guanine nucleotide exchange factor 2", "Ras GTPase-activating protein-binding protein 1", "Ras GTPase-activating protein-binding protein 2", "Ras GTPase-activating-like protein IQGAP1", "Ras GTPase-activating-like protein IQGAP2", "Ras-related C3 botulinum toxin substrate 1", "Ras-related protein Ral-A", "Ras-related protein Rap-2b", "Reader", "Receptor", "Receptor expression-enhancing protein 3", "Receptor expression-enhancing protein 4", "Receptor expression-enhancing protein 5", "Receptor-type tyrosine-protein phosphatase F", "Recombining binding protein suppressor of hairless", "Reductase", "Regulation of nuclear pre-mRNA domain-containing protein 1A", "Regulation of nuclear pre-mRNA domain-containing protein 1B", "Regulation of nuclear pre-mRNA domain-containing protein 2", "Regulator of nonsense transcripts 1", "Regulator of nonsense transcripts 2", "Rel homology transcription factor", "Remodeling and spacing factor 1", "Replication factor C subunit 2", "Replication factor C subunit 3", "Replication factor C subunit 4", "Replication factor C subunit 5", "Replication origin binding protein", "Replication protein A 70 kDa DNA-binding subunit", "Reticulocalbin-1", "Reticulocalbin-2", "Retinal dehydrogenase 2", "Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta", "Retinoic acid receptor rxr-beta", "Retinoid X receptors", "Retinoid-inducible serine carboxypeptidase", "Retinol dehydrogenase 11", "Retinol dehydrogenase 14", "Rho GDP-dissociation inhibitor 1", "Rho-associated protein kinase 1", "Rho-associated protein kinase 2", "Rho-related GTP-binding protein RhoG", "Ribonuclease H2 subunit A", "Ribonuclease P protein subunit p25-like protein", "Ribonuclease P protein subunit p30", "Ribonuclease inhibitor", "Ribonucleoprotein", "Ribonucleoprotein PTB-binding 1", "Ribonucleoside-diphosphate reductase large subunit", "Ribonucleoside-diphosphate reductase subunit M2", "Ribosomal L1 domain-containing protein 1", "Ribosomal RNA small subunit methyltransferase NEP1", "Ribosomal protein", "Ribosomal protein s6 kinase alpha-1", "Ribosomal protein s6 kinase alpha-3", "Ribosome biogenesis protein BOP1", "Ribosome biogenesis protein BRX1 homolog", "Ribosome biogenesis regulatory protein homolog", "Ribosome maturation protein SBDS", "Ribosome production factor 1", "Ribosome production factor 2 homolog", "Ribosome-recycling factor, mitochondrial", "S-adenosylhomocysteine hydrolase-like protein 1", "S-adenosylmethionine mitochondrial carrier protein", "S-adenosylmethionine synthase isoform type-2", "S-formylglutathione hydrolase", "S-methyl-5'-thioadenosine phosphorylase", "S-phase kinase-associated protein 1", "S1 RNA-binding domain-containing protein 1", "SAP30-binding protein", "SEC23-interacting protein", "SET domain", "SHC-transforming protein 1", "SLC superfamily of solute carriers", "SLC1 family of amino acid transporters", "SLC12 family of cation-coupled chloride transporters", "SLC16 family of monocarboxylate transporters", "SLC19 family of vitamin transporters", "SLC22 family of organic cation and anion transporters", "SLC25 family of mitochondrial transporters", "SLC27 family of fatty acid transporters", "SLC28 and SLC29 families of nucleoside transporters", "SLC29 family", "SLC3 and SLC7 families of heteromeric amino acid transporters (HATs)", "SLC3 family", "SLC30 zinc transporter family", "SLC35 family of nucleotide sugar transporters", "SLC38 family of sodium-dependent neutral amino acid transporters", "SLC4 family of bicarbonate transporters", "SLC5 family of sodium-dependent glucose transporters", "SLC54 Mitochondrial pyruvate carriers", "SLC55 Mitochondrial cation/proton exchangers", "SLC56 Sideroflexins", "SLC58 MagT-like magnesium transporter family", "SLC6 neurotransmitter transporter family", "SLC61 Molybdate transporter family", "SLC63 Sphingosine-phosphate transporters", "SLC64 Golgi Ca2+/H+ exchangers", "SLC7 family", "SLK subfamily", "SNARE protein", "SNW domain-containing protein 1", "SRC family", "SRPK family", "STAM-binding protein", "STE group", "STE20 family", "STE7 family", "SUMO-activating enzyme subunit 1", "SUMO-activating enzyme subunit 2", "SUN domain-containing protein 1", "SUN domain-containing protein 2", "SURP and G-patch domain-containing protein 1", "SURP and G-patch domain-containing protein 2", "SWI/SNF complex subunit SMARCC1", "SWI/SNF complex subunit SMARCC2", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1", "Sarcolemmal membrane-associated protein", "Sarcoplasmic/endoplasmic reticulum calcium ATPase 2", "Scavenger receptor class B member 1", "Sec1 family domain-containing protein 1", "Secretory carrier-associated membrane protein 1", "Secretory carrier-associated membrane protein 2", "Secretory carrier-associated membrane protein 3", "Segment polarity protein dishevelled homolog DVL-2", "Selenide, water dikinase 1", "Selenocysteine-specific elongation factor", "Sentrin-specific protease 3", "Separin", "Septin-11", "Septin-2", "Septin-6", "Septin-7", "Septin-8", "Septin-9", "Serine hydroxymethyltransferase, cytosolic", "Serine hydroxymethyltransferase, mitochondrial", "Serine palmitoyltransferase 1", "Serine palmitoyltransferase 2", "Serine protease", "Serine protease inhibitor", "Serine--tRNA ligase, cytoplasmic", "Serine--tRNA ligase, mitochondrial", "Serine/arginine repetitive matrix protein 1", "Serine/arginine-rich splicing factor 1", "Serine/arginine-rich splicing factor 10", "Serine/arginine-rich splicing factor 11", "Serine/arginine-rich splicing factor 3", "Serine/arginine-rich splicing factor 4", "Serine/arginine-rich splicing factor 5", "Serine/arginine-rich splicing factor 6", "Serine/arginine-rich splicing factor 7", "Serine/arginine-rich splicing factor 9", "Serine/threonine-protein kinase 4", "Serine/threonine-protein kinase chk2", "Serine/threonine-protein kinase mark2", "Serine/threonine-protein kinase mtor", "Serine/threonine-protein kinase n1", "Serine/threonine-protein kinase n2", "Serine/threonine-protein kinase nek9", "Serine/threonine-protein kinase osr1", "Serine/threonine-protein kinase pak 2", "Serine/threonine-protein kinase pak 4", "Serine/threonine-protein kinase plk1", "Serine/threonine-protein kinase prp4 homolog", "Serine/threonine-protein kinase tao3", "Serine/threonine-protein kinase vrk1", "Serine/threonine-protein kinase vrk2", "Serine/threonine-protein kinase wnk1", "Serine/threonine-protein kinase wnk3", "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform", "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform", "Serine/threonine-protein phosphatase 2A activator", "Serine/threonine-protein phosphatase 6 regulatory subunit 3", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit", "Serine/threonine-protein phosphatase PP1-beta catalytic subunit", "Serpin B6", "Serpin H1", "Sex comb on midleg-like protein 2", "Sialic acid synthase", "Sialidase-1", "Sideroflexin-1", "Sideroflexin-2", "Sigma intracellular receptor 2", "Signal peptidase complex catalytic subunit SEC11A", "Signal peptidase complex subunit 2", "Signal peptidase complex subunit 3", "Signal peptide peptidase-like 2A", "Signal recognition particle 14 kDa protein", "Signal recognition particle 19 kDa protein", "Signal recognition particle 54 kDa protein", "Signal recognition particle 9 kDa protein", "Signal recognition particle receptor subunit alpha", "Signal recognition particle subunit SRP68", "Signal transducer and activator of transcription 1-alpha/beta", "Signaling", "Single-stranded DNA-binding protein, mitochondrial", "Sister chromatid cohesion protein PDS5 homolog A", "Sister chromatid cohesion protein PDS5 homolog B", "Small GTPase", "Small nuclear ribonucleoprotein E", "Small nuclear ribonucleoprotein Sm D1", "Small nuclear ribonucleoprotein Sm D2", "Small nuclear ribonucleoprotein Sm D3", "Sodium bicarbonate cotransporter 3", "Sodium iodide symporter, sodium-dependent multivitamin transporter and sodium-coupled monocarboxylate transporters", "Sodium-coupled neutral amino acid transporter 2", "Sodium-dependent HCO3- transporters", "Sodium-dependent multivitamin transporter", "Sodium-dependent neutral amino acid transporter B(0)AT2", "Sodium/potassium-transporting ATPase subunit alpha-1", "Sodium/potassium-transporting ATPase subunit beta-1", "Sodium/potassium-transporting ATPase subunit beta-3", "Solute carrier family 12 member 2", "Solute carrier family 25 member 33", "Solute carrier family 25 member 40", "Solute carrier family 35 member F2", "Something about silencing protein 10", "Sorbitol dehydrogenase", "Sortilin", "Sorting nexin-1", "Sorting nexin-2", "Spermatid perinuclear RNA-binding protein", "Spermidine synthase", "Splicing factor 1", "Splicing factor 3A subunit 1", "Splicing factor 3A subunit 2", "Splicing factor 3A subunit 3", "Splicing factor 3B subunit 1", "Splicing factor 3B subunit 3", "Splicing factor 45", "Splicing factor U2AF 35 kDa subunit", "Splicing factor, arginine/serine-rich 15", "Splicing factor, proline- and glutamine-rich", "Splicing factor, suppressor of white-apricot homolog", "Splicing regulatory glutamine/lysine-rich protein 1", "Squalene monooxygenase", "Squamous cell carcinoma antigen recognized by T-cells 3", "Src substrate cortactin", "Srsf protein kinase 1", "Srsf protein kinase 2", "Staphylococcal nuclease domain-containing protein 1", "Ste20-like serine/threonine-protein kinase", "Sterol O-acyltransferase 1", "Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating", "Stomatin-like protein 2, mitochondrial", "Storage", "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial", "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial", "Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial", "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial", "Succinate-semialdehyde dehydrogenase, mitochondrial", "Sulfhydryl oxidase 2", "Superoxide dismutase [Mn], mitochondrial", "Surfeit locus protein 4", "Surfeit locus protein 6", "Survival motor neuron protein", "Synaptic functional regulator FMR1", "Synaptic vesicle glycoprotein 2A", "Synaptogyrin-2", "Synaptojanin-2-binding protein", "Synaptosomal-associated protein 23", "Synaptosomal-associated protein 29", "Syntaxin-10", "Syntaxin-12", "Syntaxin-18", "Syntaxin-3", "Syntaxin-5", "Syntaxin-6", "Syntaxin-7", "Syntaxin-8", "Syntaxin-binding protein 3", "Syntenin-1", "System A-like transporters", "T-complex protein 1 subunit alpha", "T-complex protein 1 subunit beta", "T-complex protein 1 subunit delta", "T-complex protein 1 subunit epsilon", "T-complex protein 1 subunit eta", "T-complex protein 1 subunit gamma", "T-complex protein 1 subunit theta", "T-complex protein 1 subunit zeta", "TAO subfamily", "TATA-binding protein-associated factor 2N", "TBC1 domain family member 10A", "TBC1 domain family member 10B", "TBC1 domain family member 13", "TBC1 domain family member 15", "TBC1 domain family member 4", "TBC1 domain family member 9B", "THO complex subunit 1", "THO complex subunit 2", "THO complex subunit 3", "THO complex subunit 4", "TK group", "TKL group", "TOPK family", "TP53-binding protein 1", "TTK family", "Target of EGR1 protein 1", "Targeting protein for Xklp2", "Terminal uridylyltransferase 4", "Testin", "Testis-specific Y-encoded-like protein 1", "Tgf-beta-activated kinase 1 and map3k7-binding protein 1", "Thimet oligopeptidase", "Thioredoxin domain-containing protein 12", "Thioredoxin domain-containing protein 17", "Thioredoxin domain-containing protein 9", "Thioredoxin reductase 1, cytoplasmic", "Thioredoxin-dependent peroxide reductase, mitochondrial", "Thiosulfate sulfurtransferase", "Threonine--tRNA ligase, cytoplasmic", "Threonine--tRNA ligase, mitochondrial", "Thymidine kinase family", "Thymidine kinase, cytosolic", "Thymidylate kinase", "Thymidylate kinase family", "Thymidylate synthase", "Thyroid adenoma-associated protein", "Thyroid hormone receptor-associated protein 3", "Tight junction", "Tight junction protein ZO-1", "Tight junction protein ZO-2", "Tmem38 family", "Torsin-1A", "Torsin-1B", "Trafficking protein particle complex subunit 4", "Transaminase", "Transcription activator BRG1", "Transcription cofactor", "Transcription elongation factor A protein 1", "Transcription elongation factor SPT6", "Transcription elongation regulator 1", "Transcription factor", "Transcription factor 20", "Transcription initiation factor IIB", "Transcription initiation factor TFIID subunit 7", "Transcriptional activator protein Pur-alpha", "Transcriptional repressor CTCF", "Transcriptional repressor p66-alpha", "Transcriptional repressor p66-beta", "Transferase", "Transferrin receptor protein 1", "Transformer-2 protein homolog alpha", "Transformer-2 protein homolog beta", "Transforming protein RhoA", "Transgelin-2", "Transketolase", "Translation elongation factor", "Translation factor", "Translation factor GUF1, mitochondrial", "Translation initiation factor", "Translation initiation factor IF-2, mitochondrial", "Translation release factor", "Translationally-controlled tumor protein", "Translocation protein SEC63 homolog", "Translocon-associated protein subunit alpha", "Transmembrane 9 superfamily member 2", "Transmembrane 9 superfamily member 3", "Transmembrane 9 superfamily member 4", "Transmembrane emp24 domain-containing protein 1", "Transmembrane emp24 domain-containing protein 10", "Transmembrane emp24 domain-containing protein 2", "Transmembrane emp24 domain-containing protein 5", "Transmembrane emp24 domain-containing protein 9", "Transmembrane protein 165", "Transport and Golgi organization protein 1 homolog", "Transporter", "Transportin-1", "Transportin-3", "Tricarboxylate transport protein, mitochondrial", "Trifunctional enzyme subunit alpha, mitochondrial", "Trifunctional enzyme subunit beta, mitochondrial", "Trifunctional purine biosynthetic protein adenosine-3", "Trimeric intracellular cation channel type B", "Triosephosphate isomerase", "Tripeptidyl-peptidase 1", "Tripeptidyl-peptidase 2", "Trophoblast glycoprotein", "Tropomodulin-1", "Tropomodulin-3", "Tropomyosin alpha-1 chain", "Tropomyosin alpha-3 chain", "Tropomyosin alpha-4 chain", "Tryptophan--tRNA ligase, cytoplasmic", "Tuberin", "Tubulin", "Tubulin beta chain", "Tubulin beta-2A chain", "Tubulin beta-2B chain", "Tubulin beta-3 chain", "Tubulin beta-4B chain", "Tubulin beta-6 chain", "Tubulin-folding cofactor B", "Tubulin-specific chaperone A", "Tubulin-specific chaperone D", "Tubulin-specific chaperone E", "Tudor and KH domain-containing protein", "Tudor domain", "Tuftelin-interacting protein 11", "Tumor susceptibility gene 101 protein", "Twinfilin-1", "Twinfilin-2", "Twinkle protein, mitochondrial", "Type II PI4K subfamily", "Type III PI4K subfamily", "Tyrosine--tRNA ligase, cytoplasmic", "Tyrosine--tRNA ligase, mitochondrial", "Tyrosine-protein kinase csk", "Tyrosine-protein kinase lyn", "Tyrosine-protein kinase yes", "U1 small nuclear ribonucleoprotein 70 kDa", "U1 small nuclear ribonucleoprotein A", "U2 small nuclear ribonucleoprotein A'", "U2 small nuclear ribonucleoprotein B''", "U2 snRNP-associated SURP motif-containing protein", "U3 small nucleolar RNA-associated protein 14 homolog A", "U3 small nucleolar RNA-associated protein 6 homolog", "U3 small nucleolar ribonucleoprotein protein IMP3", "U3 small nucleolar ribonucleoprotein protein IMP4", "U3 small nucleolar ribonucleoprotein protein MPP10", "U4/U6 small nuclear ribonucleoprotein Prp3", "U4/U6 small nuclear ribonucleoprotein Prp31", "U4/U6 small nuclear ribonucleoprotein Prp4", "U4/U6.U5 tri-snRNP-associated protein 1", "U4/U6.U5 tri-snRNP-associated protein 2", "U6 snRNA-associated Sm-like protein LSm2", "U6 snRNA-associated Sm-like protein LSm3", "U6 snRNA-associated Sm-like protein LSm7", "U6 snRNA-associated Sm-like protein LSm8", "UDP-glucose:glycoprotein glucosyltransferase 1", "UDP-glucuronic acid decarboxylase 1", "UMP-CMP kinase", "UV excision repair protein RAD23 homolog B", "Ubiquitin carboxyl-terminal hydrolase 1", "Ubiquitin carboxyl-terminal hydrolase 10", "Ubiquitin carboxyl-terminal hydrolase 11", "Ubiquitin carboxyl-terminal hydrolase 14", "Ubiquitin carboxyl-terminal hydrolase 15", "Ubiquitin carboxyl-terminal hydrolase 19", "Ubiquitin carboxyl-terminal hydrolase 28", "Ubiquitin carboxyl-terminal hydrolase 47", "Ubiquitin carboxyl-terminal hydrolase 5", "Ubiquitin carboxyl-terminal hydrolase 7", "Ubiquitin carboxyl-terminal hydrolase isozyme L5", "Ubiquitin conjugation factor E4 A", "Ubiquitin conjugation factor E4 B", "Ubiquitin thioesterase OTUB1", "Ubiquitin-conjugating enzyme E2 L3", "Ubiquitin-like modifier-activating enzyme 1", "Ubiquitin-like modifier-activating enzyme 5", "Ubiquitin-like modifier-activating enzyme 6", "Ubiquitin-protein ligase", "Unclassified protein", "Unconventional myosin-Ib", "Unconventional myosin-Ic", "Unconventional myosin-Id", "Unconventional myosin-Ie", "Unconventional myosin-VI", "Upstream-binding protein 1", "Uridine kinase family", "Uridine-cytidine kinase 2", "V-type ATPase", "V-type proton ATPase 116 kDa subunit a isoform 1", "V-type proton ATPase 116 kDa subunit a isoform 2", "V-type proton ATPase catalytic subunit A", "V-type proton ATPase subunit B, brain isoform", "V-type proton ATPase subunit C 1", "V-type proton ATPase subunit D", "V-type proton ATPase subunit H", "V-type proton ATPase subunit d 1", "VPS15 family", "VRK family", "Vacuolar protein sorting-associated protein 18 homolog", "Vacuolar protein sorting-associated protein 26A", "Vacuolar protein sorting-associated protein 29", "Vacuolar protein sorting-associated protein 33A", "Vacuolar protein sorting-associated protein 35", "Vacuolar protein sorting-associated protein 45", "Vacuolar protein sorting-associated protein 4A", "Vacuolar protein sorting-associated protein 52 homolog", "Very long-chain acyl-CoA synthetase", "Very long-chain specific acyl-CoA dehydrogenase, mitochondrial", "Very-long-chain enoyl-CoA reductase", "Vesicle coat protein", "Vesicle-associated membrane protein 7", "Vesicle-associated membrane protein-associated protein A", "Vesicle-associated membrane protein-associated protein B/C", "Vesicle-fusing ATPase", "Vesicular integral-membrane protein VIP36", "Vitamin K epoxide reductase complex subunit 1-like protein 1", "WD repeat and HMG-box DNA-binding protein 1", "WD repeat-containing protein 1", "WD repeat-containing protein 74", "WD repeat-containing protein 82", "WEE family", "WNK family", "Wiskott-Aldrich syndrome protein family member 2", "Writer", "X-ray repair cross-complementing protein 5", "X-ray repair cross-complementing protein 6", "Xaa-Pro dipeptidase", "YEATS domain-containing protein 2", "YEATS domain-containing protein 4", "YLP motif-containing protein 1", "Zinc finger CCCH domain-containing protein 11A", "Zinc finger CCCH domain-containing protein 15", "Zinc finger CCCH domain-containing protein 7B", "Zinc finger CCHC domain-containing protein 8", "Zinc finger MYM-type protein 2", "Zinc finger MYM-type protein 3", "Zinc finger MYM-type protein 4", "Zinc finger RNA-binding protein", "Zinc finger ZZ-type and EF-hand domain-containing protein 1", "Zinc finger protein 281", "Zinc finger protein 622", "Zinc finger protein ubi-d4", "Zinc finger transcription factor", "Zinc transporter 7", "Zyxin", "[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial", "[pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial", "c-Myc-binding protein", "eIF-2-alpha kinase activator GCN1", "eukaryotic two domain clade \"e\" sub-subfamily", "m7GpppX diphosphatase", "mRNA export factor", "mRNA polyadenylation factor", "mRNA processing factor", "mRNA splicing factor", "mRNA-decapping enzyme 1A", "pre-mRNA 3' end processing protein WDR33", "rRNA 2'-O-methyltransferase fibrillarin", "tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6", "tRNA (cytosine(34)-C(5))-methyltransferase", "tRNA dimethylallyltransferase", "tRNA pseudouridine synthase A"], "available_proteins": ["AACS", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCF1", "ABCF2", "ABHD12", "ABHD6", "ACAA1", "ACAA2", "ACAD11", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ADA", "ADAM9", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADK", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGL", "AHCY", "AHCYL1", "AIFM1", "AIMP1", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALYREF", "AMPD2", "ANAPC1", "ANO6", "ANP32B", "ANP32E", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APLP2", "APOBEC3C", "APOL2", "APP", "ARCN1", "ARFIP1", "ARFIP2", "ARG2", "ARHGDIA", "ARIH1", "ARPC1A", "ARPC3", "ARPC4", "ARVCF", "ASAH1", "ASNA1", "ASNS", "ATAD2", "ATAD3A", "ATAD3B", "ATG4B", "ATIC", "ATL2", "ATP11C", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP6", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "ATPAF1", "ATPIF1", "ATXN2L", "AUP1", "AURKB", "BAG6", "BAIAP2", "BAX", "BCAP31", "BCAS2", "BCAT2", "BCLAF1", "BLMH", "BLVRA", "BOP1", "BPNT1", "BRCA1", "BRD2", "BRD3", "BRD4", "BRD7", "BRIX1", "BUB1B", "BUB3", "BUD23", "BUD31", "BZW1", "BZW2", "C1D", "CAB39", "CACYBP", "CAD", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CBL", "CBX1", "CBX2", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CDC20", "CDC37", "CDC40", "CDC42", "CDC45", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CDKN2AIP", "CEBPZ", "CEP135", "CEP170", "CEP250", "CETN2", "CFAP20", "CHAF1A", "CHAF1B", "CHEK2", "CHERP", "CHKA", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTOP", "CHUK", "CIRBP", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLNS1A", "CLPTM1", "CLPTM1L", "CLPX", "CLSTN3", "CLTA", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT2", "CNOT7", "CNP", "COIL", "COLEC12", "COLGALT1", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS3", "COPS5", "COPS6", "COPS8", "COPZ1", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX2", "COX5A", "COX5B", "COX7A2", "COX7A2L", "COX7C", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRNKL1", "CRTAP", "CS", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTH", "CTNNA1", "CTNND1", "CTPS1", "CTPS2", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL4B", "CUL5", "CWC22", "CYB5B", "CYB5D2", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DBN1", "DBNL", "DBT", "DCAF13", "DCP1A", "DCPS", "DCTN1", "DCTN2", "DDB1", "DDI2", "DDOST", "DDT", "DECR1", "DENR", "DERL1", "DERL2", "DHCR24", "DHCR7", "DHFR", "DHX15", "DHX29", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DICER1", "DIDO1", "DIEXF", "DIS3", "DLD", "DLG1", "DLST", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DOLPP1", "DPF2", "DPH5", "DPM1", "DPP3", "DPYSL2", "DPYSL3", "DPYSL5", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DTYMK", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBP", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC4", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EEFSEC", "EFHD1", "EFL1", "EFTUD2", "EGFR", "EHD1", "EHD4", "EHHADH", "EHMT2", "EIF2A", "EIF2AK2", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3H", "EIF3I", "EIF3J", "EIF3L", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELMO2", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP3", "EMC2", "EMG1", "ENO1", "ENO2", "ENPP1", "EPHA7", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERC1", "ERH", "ERMP1", "ERO1A", "ERP29", "ESD", "ESPL1", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXO1", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EZH2", "EZR", "FAHD1", "FAM177A1", "FARSB", "FASN", "FBL", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FKBP1A", "FKBP4", "FKBP5", "FMR1", "FN3KRP", "FOXRED1", "FSCN1", "FSTL1", "FUBP1", "FUBP3", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GCAT", "GCFC2", "GCN1", "GDI1", "GDI2", "GFPT1", "GGH", "GLB1", "GLB1L2", "GLDC", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPS", "GNA13", "GNAI2", "GNAI3", "GNE", "GNG12", "GNG5", "GNPDA1", "GNS", "GOLGA2", "GOSR1", "GPAT4", "GPATCH4", "GPD2", "GPI", "GPKOW", "GPR107", "GPR89B", "GRHPR", "GRPEL1", "GRSF1", "GSK3B", "GSPT1", "GSR", "GSS", "GTF2B", "GTF2F1", "GTF2F2", "GTF3C3", "GTF3C5", "GTPBP1", "GUF1", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADHA", "HADHB", "HAT1", "HBS1L", "HCCS", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HEATR1", "HEATR6", "HELZ", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIRA", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLCS", "HM13", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGN1", "HMGN3", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HOOK2", "HPRT1", "HPSE", "HSD17B10", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HTATSF1", "HUWE1", "IARS", "IARS2", "IDE", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMP4", "IMPAD1", "IMPDH2", "INTS11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "ITCH", "ITGB1", "ITPA", "IVD", "JMJD6", "KARS", "KAT7", "KCTD12", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KHDRBS1", "KHDRBS3", "KHSRP", "KIF11", "KIF14", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRR1", "KYAT3", "L2HGDH", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS2", "LBR", "LDHA", "LDHB", "LETM1", "LGALS3", "LGMN", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LNPEP", "LONP1", "LPCAT1", "LRRC47", "LRRFIP2", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM7", "LSM8", "LTN1", "LYN", "MACF1", "MAGED1", "MAGED2", "MAGT1", "MAN1A1", "MAN1A2", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K4", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCH5", "MARK2", "MARK3", "MAT2A", "MBOAT7", "MCAM", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED12", "MED14", "MED21", "MED25", "METAP1", "METTL15", "MFAP1", "MFN1", "MFSD3", "MFSD5", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MIPEP", "MKRN2", "MMS19", "MOB4", "MORF4L1", "MORF4L2", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRPL1", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL23", "MRPL24", "MRPL38", "MRPL39", "MRPL43", "MRPL44", "MRPL47", "MRPL48", "MRPL49", "MRPL9", "MRPS11", "MRPS16", "MRPS18A", "MRPS2", "MRPS27", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTM1", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MUT", "MYBBP1A", "MYCBP", "MYEF2", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO6", "NAA10", "NAA15", "NAA50", "NADK2", "NAE1", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NBN", "NCAPD2", "NCAPD3", "NCBP1", "NCL", "NCOA5", "ND1", "NDRG3", "NDUFA10", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA8", "NDUFA9", "NDUFB1", "NDUFB11", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFC2", "NDUFS1", "NDUFS2", "NDUFS6", "NDUFS7", "NEDD4", "NEDD4L", "NEK9", "NEU1", "NFRKB", "NFS1", "NHP2", "NIPBL", "NISCH", "NKRF", "NLN", "NLRX1", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOC4L", "NOL6", "NOM1", "NONO", "NOP14", "NOP56", "NOP58", "NOP9", "NOVA1", "NOVA2", "NPEPPS", "NPM1", "NRBP1", "NRDC", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE3", "NSUN2", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDCD2", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUF2", "NUP107", "NUP153", "NUP160", "NUP210", "NUP214", "NUP37", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "OAT", "OCIAD1", "OCLN", "OCRL", "OLA1", "OPA1", "ORC2", "ORC3", "ORC5", "OSGEP", "OTUB1", "OTUD7B", "OXA1L", "OXSR1", "P3H1", "P3H3", "P3H4", "PACSIN2", "PAICS", "PAIP1", "PAK2", "PAK4", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PAXBP1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PDCD11", "PDCD4", "PDCD5", "PDCD6IP", "PDE12", "PDE6D", "PDK3", "PDLIM1", "PDLIM5", "PDP1", "PDPR", "PDS5A", "PDS5B", "PDXK", "PDZD11", "PEBP1", "PECR", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PGD", "PGK1", "PGLS", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHC2", "PHF10", "PHF14", "PHF3", "PHF6", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGK", "PIK3C2A", "PIK3R4", "PINX1", "PIP4K2C", "PIR", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PKP2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMS1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POFUT2", "POGZ", "POLA2", "POLD2", "POLDIP3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3F", "POLRMT", "POMGNT2", "PPA1", "PPA2", "PPAT", "PPIL1", "PPM1F", "PPM1G", "PPME1", "PPP1CA", "PPP1CB", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP6R3", "PPT1", "PPT2", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX6", "PREB", "PREP", "PRIM1", "PRKAA1", "PRKACA", "PRKAG1", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF3", "PRPF31", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC2A", "PRRC2B", "PRRC2C", "PSIP1", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSMF1", "PSPC1", "PTCD1", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPRF", "PUDP", "PUM1", "PURA", "PUS1", "PWP1", "PXMP2", "PYGB", "PYGL", "QARS", "QKI", "QRICH1", "QRSL1", "QSOX2", "RAB3GAP2", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RAD23B", "RAE1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RAVER1", "RBBP6", "RBFOX2", "RBM12", "RBM12B", "RBM14", "RBM17", "RBM19", "RBM22", "RBM26", "RBM27", "RBM3", "RBM4", "RBMX", "RBMXL1", "RBPJ", "RCL1", "RCN1", "RCN2", "RDH11", "RDH14", "RDX", "RECQL", "RECQL4", "RECQL5", "REEP3", "REEP4", "REEP5", "REL", "REPS1", "RFC2", "RFC3", "RFC4", "RFC5", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RILPL1", "RNASEH2A", "RNF14", "RNH1", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRM1", "RRM2", "RRS1", "RSF1", "RSL1D1", "RTCA", "RXRB", "S100A10", "S100A11", "S100A13", "SAE1", "SAP18", "SAP30BP", "SARS", "SARS2", "SART1", "SART3", "SATB2", "SBDS", "SBNO1", "SC5D", "SCAF4", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCFD1", "SCML2", "SCO1", "SCO2", "SCPEP1", "SDCBP", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEH1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT8", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD7", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B3", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SHC1", "SHMT1", "SHMT2", "SIN3A", "SIN3B", "SIRT1", "SIRT2", "SKP1", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC30A7", "SLC35B2", "SLC35F2", "SLC38A2", "SLC3A2", "SLC4A7", "SLC5A6", "SLC6A15", "SLC7A1", "SLK", "SLMAP", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMN1*", "SNAP23", "SNAP29", "SND1", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SOAT1", "SOD2", "SORD", "SORT1", "SPAG9", "SPCS2", "SPCS3", "SPNS1", "SPPL2A", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SREK1", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRRM1", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "STAG1", "STAG2", "STAMBP", "STAT1", "STK4", "STOM", "STOML2", "STRBP", "STT3A", "STT3B", "STX10", "STX12", "STX18", "STX3", "STX5", "STX6", "STX7", "STX8", "STXBP3", "SUCLA2", "SUCLG2", "SUGP1", "SUGP2", "SUN1", "SUN2", "SUPT16H", "SUPT6H", "SURF4", "SURF6", "SUZ12", "SV2A", "SYNCRIP", "SYNGR2", "SYNJ2BP", "TAB1", "TAF15", "TAF7", "TAGLN2", "TAOK3", "TAP1", "TAP2", "TARS", "TARS2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TCEA1", "TCERG1", "TCF20", "TCP1", "TDRKH", "TECR", "TES", "TFCP2", "TFIP11", "TFRC", "THADA", "THOC1", "THOC2", "THOC3", "THOP1", "THRAP3", "TJP1", "TJP2", "TK1", "TKT", "TM9SF2", "TM9SF3", "TM9SF4", "TMED1", "TMED10", "TMED2", "TMED5", "TMED9", "TMEM165", "TMEM38B", "TMEM97", "TMOD1", "TMOD3", "TMPO", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM40", "TOP1", "TOP3A", "TOR1A", "TOR1B", "TP53", "TP53BP1", "TP53BP2", "TPBG", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAP1", "TRAPPC4", "TRIT1", "TRMT6", "TROVE2", "TRUB1", "TSC2", "TSFM", "TSG101", "TSPYL1", "TST", "TSTA3", "TTK", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC9", "TXNRD1", "TYMS", "U2AF1", "U2SURP", "UBA1", "UBA2", "UBA5", "UBA6", "UBE2L3", "UBE4A", "UBE4B", "UBP1", "UCHL5", "UCK2", "UGCG", "UGGT1", "UNC119B", "UPF1", "UPF2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "USO1", "USP1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP28", "USP39", "USP47", "USP5", "USP7", "UTP11", "UTP14A", "UTP3", "UTP6", "UXS1", "VAMP7", "VAPA", "VAPB", "VBP1", "VKORC1L1", "VPS18", "VPS26A", "VPS29", "VPS33A", "VPS35", "VPS45", "VPS4A", "VPS52", "VRK1", "VRK2", "WARS", "WASF2", "WDHD1", "WDR1", "WDR33", "WDR74", "WDR82", "WIZ", "WNK1", "WNK3", "XAB2", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "YARS", "YARS2", "YEATS2", "YEATS4", "YES1", "YLPM1", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H15", "ZC3H7B", "ZCCHC11", "ZCCHC8", "ZFR", "ZMPSTE24", "ZMYM2", "ZMYM3", "ZMYM4", "ZNF207", "ZNF281", "ZNF598", "ZNF622", "ZW10", "ZYX", "ZZEF1"], "leading_proteins": ["ACOX1", "ACOX3", "ACP6", "ADPGK", "AFG3L2", "AIFM1", "AIP", "AKT1", "AKT2", "ALDH1A2", "ALDH1B1", "ALG1", "AP3M1", "AP3S1", "APEH", "APOL2", "ARFIP2", "ASNA1", "ATG4B", "ATL2", "ATP1A1", "ATP2A2", "ATP2C1", "ATP5B", "ATP5F1", "ATP6", "ATP6V0A1", "ATP6V0A2", "ATP6V1B2", "ATP6V1D", "BAG6", "CALM3", "CALU", "CBX1", "CBX2", "CBX3", "CCNA2", "CCT2", "CCT3", "CDC37", "CDC45", "CDK1", "CDK11B", "CDK2", "CDK4", "CEP135", "CEP250", "CETN2", "CHMP7", "CLCC1", "CLNS1A", "CLUH", "COPB2", "COPS8", "COX2", "COX7A2", "CPVL", "CTPS1", "CTPS2", "CYB5B", "CYB5D2", "CYFIP1", "CYP51A1", "DCTN2", "DHCR24", "DNM1L", "DOLPP1", "DVL2", "EEA1", "EIF2D", "EIF3H", "ELP1", "ERAP1", "ERAP2", "ERC1", "ETNK1", "EXOC4", "EXOC6", "FAM177A1", "FUBP1", "FUBP3", "GALNT1", "GALNT2", "GAPVD1", "GOLGA2", "GOSR1", "GPD2", "GPR89B", "GYG1", "HDGF", "HDGFL2", "HM13", "HNRNPK", "HOOK2", "HPRT1", "IGBP1", "IGF2BP2", "IMPAD1", "IPO4", "IPO5", "IPO9", "KDELR1", "KDELR3", "KDM1B", "KIF14", "KIF1B", "KIF5B", "LAMB1", "LBR", "LETM1", "LMAN1", "MAN1A1", "MAN1A2", "MAP2K1", "MAP7D1", "MAPK1", "MAPK3", "MAPRE2", "MCL1", "MFN1", "MIA2", "MIA3", "MICU1", "MICU2", "MPC2", "MPHOSPH8", "MPRIP", "MPV17L2", "MSMO1", "MTCH2", "MYL6", "NAMPT", "NAP1L1", "NAP1L4", "ND1", "NISCH", "NLN", "NNT", "NOVA2", "NPEPPS", "NT5C2", "NT5C3B", "NT5DC2", "NUCB2", "NUP37", "NUP88", "NUP93", "OCIAD1", "OCLN", "OPA1", "ORC2", "P3H1", "P3H3", "P3H4", "PDCD5", "PDP1", "PEX14", "PEX5", "PFDN2", "PGRMC2", "PI4K2A", "PI4KA", "PIK3C2A", "PIP4K2C", "PITRM1", "PLA2G15", "PLD6", "PMPCA", "POFUT2", "PPAT", "PPP2R1B", "PRCP", "PRMT3", "PSMD7", "PTPRF", "PXMP2", "QSOX2", "RABGAP1", "RAPGEF2", "RCN1", "RCN2", "REL", "REPS1", "ROCK2", "RPN1", "RPS6KA1", "RRM2", "S100A13", "SCARB1", "SCO1", "SDF4", "SEC11A", "SEC23B", "SEPT6", "SET", "SETD7", "SFXN2", "SIN3B", "SLC12A2", "SLC25A10", "SLC25A12", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A21", "SLC25A26", "SLC25A32", "SLC25A33", "SLC25A40", "SLC30A7", "SLC35B2", "SLC35F2", "SLC38A2", "SLC4A7", "SLC7A1", "SNAP29", "SNX2", "SPAG9", "SRPK2", "SSR1", "STT3A", "STX18", "STX3", "STX5", "STX6", "SUN1", "SUN2", "SURF4", "SYNGR2", "SYNJ2BP", "TAP1", "THOP1", "TM9SF2", "TM9SF3", "TM9SF4", "TMED10", "TMED2", "TMED5", "TMED9", "TMEM165", "TMEM97", "TNPO1", "TOMM20", "TPM1", "TPM4", "TSC2", "TTYH3", "TUBB", "TUBB2A", "TUBB3", "TUBB4B", "TUBB6", "TUBGCP2", "TXLNA", "UBE4B", "UGCG", "UNC119B", "UQCR10", "UQCRC2", "USO1", "USP15", "USP28", "USP47", "VKORC1L1", "VPS35", "XPO4", "ZADH2", "ZMPSTE24"]} \ No newline at end of file diff --git a/pharos_protein_category/advanced/idx2term.json b/pharos_protein_category/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..6e0847ffc649d08286e63465c7dfff7898d31ecd --- /dev/null +++ b/pharos_protein_category/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Tbio"} \ No newline at end of file diff --git a/pharos_protein_category/advanced/plot_0.png b/pharos_protein_category/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..71d83c95df3622280cbf744d2bbf83c061127272 --- /dev/null +++ b/pharos_protein_category/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f6a70bddbcbbd5c871c262266663739e0af4a2199fbaacaa1eedab5ce4e11dab +size 219207 diff --git a/pharos_protein_category/basic/idx2term.json b/pharos_protein_category/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..ddd662d46a4f8971ba47d18342352a728e89ddee --- /dev/null +++ b/pharos_protein_category/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Tbio", "1": "Tclin"} \ No newline at end of file diff --git a/pharos_protein_category/basic/plot_0.png b/pharos_protein_category/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..9f708cf803a556cf7dedff7398cf6ef9763cf5c5 --- /dev/null +++ b/pharos_protein_category/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9f047ea87c78a783e59f6fa40c9d353020ab52176d801562c275a9db6786b602 +size 131436 diff --git a/pharos_protein_category/basic/plot_1.png b/pharos_protein_category/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..c2b9863c8471c9d1d502c7a0d41af69e06cdb791 --- /dev/null +++ b/pharos_protein_category/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ab388541c89187ab75a38aa3eac366ccd4a2a0cb2367da6eb18aa06fef0cc23e +size 135869 diff --git a/pharos_protein_category/consensus.joblib b/pharos_protein_category/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..32d9ae5dffdae0009f06220c3e727876deb4f7ce --- /dev/null +++ b/pharos_protein_category/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:303d93e681ef9118f5434a6263d5862d06f5588dccac0406470b1b3caf71d2bb +size 84000 diff --git a/pharos_protein_category/df_merge.tsv b/pharos_protein_category/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..96034b31c8182797b9738a8255f22d2294392dbf --- /dev/null +++ b/pharos_protein_category/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Tbio 513 2595 3.259903118054281 0.001114502763198 467.6796116504854 2434.25 -0.5416405556668178 0.3215141878443288 119.73666199244032 234.70955636597876 4.704421961664106 0.4116627836259234 0.791687416700373 0.9986573293116048 0.9256935557235624 0.5292145199259156 0.0003124678284228 diff --git a/pharos_protein_category/metrics.json b/pharos_protein_category/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..3f3e7f68b03cca4ba01dda513cff3dda1fedd092 --- /dev/null +++ b/pharos_protein_category/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3381, + "annotations_size": 4, + "title": "Average number of proteins per term", + "value": 845.0 +} \ No newline at end of file diff --git a/pharos_protein_category/paths.json b/pharos_protein_category/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..c7aca3aff858e1fa325f3daa762ccce8abc51777 --- /dev/null +++ b/pharos_protein_category/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_protein_category/fragment/C317/C317_val_log2fc"} \ No newline at end of file diff --git a/pharos_protein_category/result.tsv b/pharos_protein_category/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..a7e50d543277ccbd2b19b14893d6294aebfa3ceb --- /dev/null +++ b/pharos_protein_category/result.tsv @@ -0,0 +1,3 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Tbio 0.2079226589400168 3.2599031180542815 0.001114502763198 0.0044505638901628 0.004458011052792 2595 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513 +Tclin 0.3272658629361943 1.2345428365151625 0.2170006948248013 0.6241232122761584 0.4340013896496026 96 P55011,P62942,P03886,P28074,P20618,Q06203,P21964,Q16739,Q86Y39,P56556,O43676,P00813,P00374,O96000,P38435,P49721,Q99720,P31350,Q9Y2I1,P0DP25 20 diff --git a/pharos_protein_category/selections.json b/pharos_protein_category/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..117e9a801fa2dd3d30c0a9e1c0be47bc1e86cb29 --- /dev/null +++ b/pharos_protein_category/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Tbio", "Tchem", "Tclin", "Tdark"], "available_proteins": ["AAAS", "AACS", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABHD10", "ABHD12", "ABHD6", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ADA", "ADAM17", "ADAM9", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT1S1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG2", "ALG5", "ALKBH5", "ALYREF", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APBB1", "APC", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOBEC3C", "APOL2", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID2", "ARIH1", "ARL1", "ARL10", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARL8B", "ARMC1", "ARMC10", "ARMC6", "ARMC8", "ARMCX3", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARVCF", "ASAH1", "ASCC2", "ASCC3", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG4B", "ATG9A", "ATIC", "ATL2", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPAF2", "ATPIF1", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKB", "B4GAT1", "BABAM1", "BABAM2", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAP18", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BDH2", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD2", "BRD3", "BRD4", "BRD7", "BRD8", "BRI3BP", "BRIX1", "BROX", "BSG", "BTF3", "BTRC", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C12orf73", "C14orf2", "C16orf58", "C17orf80", "C19orf25", "C19orf47", "C19orf70", "C1D", "C1QBP", "C1orf123", "C1orf35", "C2CD2L", "C2CD5", "C3orf58", "C5orf15", "C5orf24", "C5orf51", "C8orf59", "CAB39", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAMLG", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN7", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CAST", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC127", "CCDC134", "CCDC138", "CCDC22", "CCDC47", "CCDC58", "CCDC6", "CCDC8", "CCDC86", "CCDC93", "CCDC97", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC20", "CDC23", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC6", "CDC73", "CDCA2", "CDCA5", "CDCA7L", "CDCA8", "CDH2", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDKN2AIP", "CDR2L", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPV", "CEP135", "CEP170", "CEP250", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CGGBP1", "CGN", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHP1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSTN3", "CLTA", "CLTC", "CLU", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT10", "CNOT11", "CNOT2", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COG3", "COG7", "COIL", "COLEC12", "COLGALT1", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "COQ8B", "COQ9", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX18", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CREB1", "CREG1", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CRYZL1", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTH", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CUTA", "CWC15", "CWC22", "CWF19L1", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCD", "DCP1A", "DCP2", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DECR1", "DEK", "DENND4C", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS4", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB4", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPM1", "DPP3", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS3L", "DUSP12", "DUSP3", "DUT", "DVL2", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFHD1", "EFL1", "EFTUD2", "EGFR", "EHD1", "EHD4", "EHHADH", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENPP1", "ENSA", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPDR1", "EPHA7", "EPHX1", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EYA4", "EZH2", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAHD2A", "FAM114A2", "FAM120A", "FAM120B", "FAM129B", "FAM136A", "FAM162A", "FAM177A1", "FAM208A", "FAM210B", "FAM213A", "FAM3C", "FAM49B", "FAM8A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD5", "FAU", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNBP1L", "FNBP4", "FNDC3A", "FOXK1", "FOXK2", "FOXRED1", "FSCN1", "FSTL1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GGH", "GGPS1", "GHDC", "GHITM", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA13", "GNAI2", "GNAI3", "GNB1L", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA4", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLPH3L", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPR107", "GPR108", "GPR89B", "GPRASP2", "GPS1", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS4", "HAUS5", "HAUS6", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDGFL2", "HDHD2", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HEXA", "HEXB", "HEXIM1", "HGH1", "HGS", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIRA", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN3", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK2", "HOXD13", "HP1BP3", "HPRT1", "HPS3", "HPS6", "HPSE", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBIP", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPAD1", "IMPDH2", "INA", "INCENP", "INF2", "INTS1", "INTS11", "INTS12", "INTS13", "INTS14", "INTS3", "INTS4", "INTS7", "INTS9", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRS4", "ISCU", "ISOC1", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITM2B", "ITM2C", "ITPA", "ITPRIP", "IVD", "IWS1", "JAGN1", "JMJD6", "JPT2", "JUP", "KARS", "KAT7", "KCTD12", "KCTD5", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1468", "KIAA2013", "KIF11", "KIF14", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KNOP1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAMTOR3", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LPGAT1", "LRBA", "LRCH2", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC57", "LRRC59", "LRRC8C", "LRRFIP2", "LRSAM1", "LRWD1", "LSG1", "LSM12", "LSM14B", "LSM2", "LSM3", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L", "LUC7L2", "LUC7L3", "LUZP1", "LYAR", "LYN", "LYPLA1", "LYRM2", "LZIC", "LZTFL1", "LZTS2", "MACF1", "MAD2L1", "MAGED1", "MAGED2", "MAGT1", "MAK16", "MAN1A1", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K4", "MAP4", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARCKSL1", "MARK2", "MARK3", "MARS", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBOAT7", "MCAM", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MEAF6", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED21", "MED23", "MED24", "MED25", "MED4", "MEN1", "MEPCE", "MESD", "METAP1", "METTL13", "METTL15", "MFAP1", "MFF", "MFN1", "MFSD10", "MFSD3", "MFSD5", "MGEA5", "MGME1", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MIF", "MINDY3", "MINPP1", "MIOS", "MIPEP", "MKI67", "MKRN2", "MLEC", "MMAB", "MMS19", "MMS22L", "MOB4", "MOGS", "MON2", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPDZ", "MPG", "MPHOSPH10", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRC2", "MRE11", "MRGBP", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL55", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTM1", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MTX3", "MUT", "MXRA7", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO6", "NAA10", "NAA15", "NAA40", "NAA50", "NACC1", "NADK2", "NAE1", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCBP1", "NCBP3", "NCDN", "NCK1", "NCK2", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "NDC1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFC2", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NEU1", "NF2", "NFRKB", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIPSNAP3A", "NISCH", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NME3", "NME7", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NRBP1", "NRDC", "NRP1", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDT1", "NUDT12", "NUDT16L1", "NUDT21", "NUDT5", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "OCRL", "ODR4", "OGDH", "OGFOD3", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "ORC5", "OS9", "OSBP", "OSBPL11", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD7B", "OXA1L", "OXSR1", "P3H1", "P3H3", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1IP1", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PAOX", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATJ", "PAWR", "PAXBP1", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH19", "PCID2", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE4DIP", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDP1", "PDPR", "PDS5A", "PDS5B", "PDSS2", "PDXK", "PDZD11", "PEBP1", "PECR", "PEF1", "PELP1", "PEPD", "PES1", "PEX14", "PEX16", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF14", "PHF3", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHRF1", "PI4K2A", "PI4KA", "PI4KB", "PIBF1", "PICALM", "PIGK", "PIGL", "PIGS", "PIGT", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PKP2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POFUT1", "POFUT2", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3F", "POLRMT", "POMGNT2", "PON2", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP1R9B", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PRAF2", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PWWP2A", "PXMP2", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "PYM1", "QARS", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABEP1", "RABGAP1", "RABGGTA", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBFOX2", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "RECQL5", "REEP3", "REEP4", "REEP5", "REL", "REPS1", "RER1", "RETREG2", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RICTOR", "RIDA", "RIF1", "RILPL1", "RINT1", "RIOX1", "RIOX2", "RMDN1", "RMDN3", "RNASEH2A", "RNASET2", "RNF114", "RNF14", "RNF20", "RNF219", "RNF40", "RNH1", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS19BP1", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSU1", "RTCA", "RTCB", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "RXRB", "S100A10", "S100A11", "S100A13", "SAAL1", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SASS6", "SATB2", "SBDS", "SBNO1", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDCCAG3", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT8", "SEPT9", "SERAC1", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHC1", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIKE1", "SIN3A", "SIN3B", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC30A7", "SLC35A4", "SLC35B2", "SLC35F2", "SLC38A2", "SLC3A2", "SLC4A1AP", "SLC4A7", "SLC5A6", "SLC6A15", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLMAP", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG8", "SMG9", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SNAP23", "SNAP29", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG5", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPECC1", "SPECC1L", "SPEN", "SPNS1", "SPOUT1", "SPPL2A", "SPR", "SPRYD4", "SPRYD7", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRBD1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAU1", "STAU2", "STIP1", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX3", "STX5", "STX6", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACO1", "TAF15", "TAF4", "TAF7", "TAGLN2", "TALDO1", "TAMM41", "TAOK3", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCF25", "TCOF1", "TCP1", "TDP2", "TDRKH", "TECR", "TELO2", "TENM3", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THADA", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM13", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TIMM9", "TIMMDC1", "TJP1", "TJP2", "TK1", "TKT", "TLN1", "TM9SF2", "TM9SF3", "TM9SF4", "TMA16", "TMCO1", "TMED1", "TMED10", "TMED2", "TMED5", "TMED9", "TMEM109", "TMEM11", "TMEM126A", "TMEM14C", "TMEM160", "TMEM165", "TMEM167A", "TMEM177", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM30A", "TMEM33", "TMEM38B", "TMEM43", "TMEM59", "TMEM70", "TMEM97", "TMF1", "TMLHE", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOM1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOPBP1", "TOR1A", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TOX4", "TP53", "TP53BP1", "TP53BP2", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRIT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPO", "TSPYL1", "TSR1", "TSR2", "TST", "TSTA3", "TTC1", "TTC19", "TTC21B", "TTC26", "TTC27", "TTC37", "TTC38", "TTC4", "TTC5", "TTF2", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC16", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UACA", "UAP1", "UBA1", "UBA2", "UBA5", "UBA6", "UBAC1", "UBAP2", "UBAP2L", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBL5", "UBLCP1", "UBN2", "UBP1", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "UMPS", "UNC119B", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "URB2", "UROD", "USE1", "USMG5", "USO1", "USP1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP28", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "UXS1", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VASP", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VPS13A", "VPS18", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS51", "VPS52", "VPS53", "VRK1", "VRK2", "VTA1", "WAPL", "WARS", "WARS2", "WASF2", "WASHC4", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR36", "WDR41", "WDR43", "WDR45B", "WDR46", "WDR5", "WDR6", "WDR61", "WDR73", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIZ", "WLS", "WNK1", "WNK3", "WRAP53", "WRAP73", "WTAP", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YBX1", "YEATS2", "YEATS4", "YES1", "YIF1A", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM2", "ZMYM3", "ZMYM4", "ZMYND8", "ZNF207", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF598", "ZNF622", "ZNF638", "ZNF687", "ZPR1", "ZRANB2", "ZW10", "ZYX", "ZZEF1"], "leading_proteins": ["ABHD10", "ACAT2", "ACOX1", "ACOX3", "ACP6", "ACSL6", "ACTN1", "ACTN2", "ACTN4", "ADA", "ADD1", "ADD3", "ADI1", "ADPGK", "AFG3L2", "AGK", "AGPS", "AIFM1", "AIP", "AKAP9", "ALDH1A2", "ALDH1B1", "ALDH3A2", "ALG1", "ALG11", "ANAPC5", "ANKLE2", "ANO6", "AP3M1", "APC", "APOL2", "ARFIP2", "ARIH1", "ARMC1", "ARMC8", "ARPC2", "ASNA1", "ATAD3A", "ATAD3B", "ATG4B", "ATL2", "ATP2A2", "ATP2C1", "ATP5B", "ATP5F1", "ATP6", "ATP6V0A1", "ATP6V0A2", 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file mode 100644 index 0000000000000000000000000000000000000000..afc0d0a0bb6bc80eb03b87f9b4057fe61a267814 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:44451cf94821d72fe022a764e0c5d4984977905eca6ab9cb2c2ced95de45d85e +size 140778 diff --git a/protein_atlas_biological_process/consensus.joblib b/protein_atlas_biological_process/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..3446da4f0350e2345a778095181c188bb46fcdf0 --- /dev/null +++ b/protein_atlas_biological_process/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:648c97c46649e05052750859a28b6f89db01dbc926dec19b8d775fdc31e0e3b4 +size 82360 diff --git a/protein_atlas_biological_process/df_merge.tsv b/protein_atlas_biological_process/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..5a21bd8abc39c0086ee6671f8d6a5d7c7f9a0399 --- /dev/null +++ b/protein_atlas_biological_process/df_merge.tsv @@ -0,0 +1,6 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Hydrogen ion transport 3 20 2.4418169860141963 0.0146135527885971 6.152912621359223 19.560679611650485 0.8019462838912398 0.3170771992837126 2.890966221074556 1.405159537040464 1.2709247974732976 0.29451915785821 0.0005242473055266 0.0004265388560116 0.0002069103237917 0.0064140084647031 0.0160305095638712 +Translocation 12 50 2.015795124146224 0.043821403637809 12.434466019417476 47.86165048543689 1.1297087783550883 0.3515144245437065 6.687771513864753 3.601211391947168 1.550426642680832 0.3811939235350816 0.0128049621992529 0.0053226708337122 0.0055234944679999 0.0090935958038613 1.0927698286596184e-05 +Cilium biogenesis/degradation 8 24 1.9994694364142025 0.0455575855826784 5.446601941747573 20.866504854368937 0.3396906765452693 0.5906297977682861 3.620272358310317 4.46280685953475 0.8185723236304511 0.3156141674317883 0.8220788101288086 1.0 0.7411972663513849 0.439035842430691 0.3667122568203679 +Ion transport 22 58 1.97819395241284 0.0479068307131071 19.82766990291262 54.68446601941748 1.177785596906995 0.303722365376275 8.99659651977233 7.41832233515522 1.8666057057567336 0.3607289685223158 0.2095526604669754 0.0644630682008785 0.1133516249606659 0.0966593788375632 0.0253263094269786 +Cell shape 4 6 1.974409171229643 0.0483352360527638 3.2864077669902914 5.825242718446602 0.1869294250056881 0.5125368926243891 1.5581011933991042 0.5106094676623187 0.9778327494017148 0.3234810691378865 1.0 1.0 1.0 1.0 0.0098879726868235 diff --git a/protein_atlas_biological_process/metrics.json b/protein_atlas_biological_process/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..9a42f3ffccdcfe61e1828cf05cd4ebb585d49504 --- /dev/null +++ b/protein_atlas_biological_process/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3381, + "annotations_size": 173, + "title": "Average number of proteins per term", + "value": 31.797687861271676 +} \ No newline at end of file diff --git a/protein_atlas_biological_process/paths.json b/protein_atlas_biological_process/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..f7d02947c9b9d0b8d4d33dcb409a9967677b37ff --- /dev/null +++ b/protein_atlas_biological_process/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_biological_process/fragment/C317/C317_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_biological_process/result.tsv b/protein_atlas_biological_process/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..39bb68580404b6520ab9654716a1c88960286ffc --- /dev/null +++ b/protein_atlas_biological_process/result.tsv @@ -0,0 +1,53 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Hydrogen ion transport 0.600305561771152 2.4418169860141963 0.0146135527885971 0.9216680084274282 0.4652381950307701 20 P00846,O75964,Q93050 3 +Translocation 0.5173289750322742 2.015795124146224 0.043821403637809 0.9995702161320652 0.4652381950307701 50 O75381,O14925,Q9BTX1,O60830,Q9Y5J7,Q9Y5J9,Q9NS69,Q8TD16,Q99595,Q99567,Q15629,P41208 12 +Cilium biogenesis/degradation 0.5399387367583737 1.9994694364142025 0.0455575855826784 0.9996861635317296 0.4652381950307701 24 Q9H3S7,Q9BV73,O95721,Q9P2S5,O95684,Q96C92,Q8NCM8,A6NIH7 8 +Ion transport 0.4945381079923638 1.97819395241284 0.0479068307131071 0.9997950986880964 0.4652381950307701 58 P55011,Q96QD8,Q8NEW0,Q9BPX6,P00846,P0CG08,P05023,O75964,Q9Y6M7,Q93050,P06576,P98194,P21796,Q96S66,Q9Y487,Q4KMQ2,P45880,Q9C0H2,Q6P4Q7,P16615,Q9Y5K8,Q9NWR8 22 +Cell shape 0.7617790887100717 1.974409171229643 0.0483352360527638 0.999810447204998 0.4652381950307701 6 Q7L576,P35579,P35580,Q7Z406 4 +Sugar transport 0.9467283311410044 1.924821980884088 0.0542516330974942 0.999935556546492 0.4652381950307701 3 P31751 1 +Glycogen biosynthesis 0.7608824349135914 1.765880913724017 0.0774158299119149 0.9999991168433168 0.5151130221062035 5 P13807,P31751,P31749 3 +ATP synthesis 0.6623240981704288 1.675951103275276 0.0937477706419833 0.9999999598123868 0.5502366479786498 8 P00846 1 +ER-Golgi transport 0.4699901830237137 1.6585059928530104 0.0972153789305036 0.9999999792958052 0.5502366479786498 54 O95249,Q5JRA6,Q9NR31,O43731,O95197,Q9Y282,Q9P2W9,O60763,Q15363,P49069,O95070,Q12981,O15027,Q15437,P49755,P24390 16 +Sphingolipid metabolism 0.5889673645214707 1.5797437331563262 0.1141655659253109 0.9999999992201832 0.5502366479786498 11 Q16739,Q06136 2 +Spermatogenesis 0.4784333688126084 1.5241761449346334 0.1274647154183068 0.9999999999430546 0.5502366479786498 26 Q9H6S0,Q9BY67,Q15019,O94901,P46379,Q9Y2W6,Q8NB90,Q08J23,Q8N2A8,Q14997,Q9Y508,Q14141 12 +Calcium transport 0.6298691938031479 1.515614605771414 0.1296168316574346 0.9999999999628538 0.5502366479786498 8 P16615,Q9NWR8,P98194,Q9BPX6 4 +Nucleotide metabolism 0.5491214803575584 1.502431044353907 0.1329858238915449 0.9999999999810096 0.5502366479786498 13 P00813,Q969T7 2 +Apoptosis 0.3670659366426889 1.5001194495555663 0.1335834636711173 0.9999999999831451 0.5502366479786498 130 P31751,Q9H2J4,P46379,O95197,O60313,Q03164,Q12981,O14737,O95470,P42858,P61289,Q9H8M7,Q96TC7,P10909,P31749,O60333,Q96A26,Q96KA5,P21796,Q9UHX1,O43464,O15294,Q13501,P09601,Q9NR28,Q9UDX5,O95831,Q15276,Q9Y2I1,Q13232,Q9BXK5 31 +Peroxisome biogenesis 0.7263459986349219 1.4097890468994654 0.1586019817714516 0.999999999999894 0.6097365076991366 4 P40855 1 +Amino-acid transport 0.6000477598470325 1.3667629621514517 0.171699615543738 0.999999999999993 0.6121412041513048 8 Q6P4A7,P30825 2 +Immunity 0.3481355530630118 1.2538539810198015 0.2098950842978537 1.0 0.6431814052022096 83 P12956,P46379,P17812,Q9UQ84,P10909,Q9NZ08,Q9NUD5,Q8WXW3,Q07021,Q15233,Q03518,Q13501,Q9Y3Z3,Q9BWS9,Q9UN86,Q9H2U1,Q8WXF1,P14174,Q6P179,Q8IXJ6,P26583,P23246,P09429 23 +Respiratory chain 0.4401849645678138 1.2110714074808435 0.2258680385304761 1.0 0.6672360566866387 35 Q6DKK2,Q9UDW1,P22695,P00403,P03886,O14949,O43676,Q86Y39 8 +Phospholipid metabolism 0.4773677626568013 1.2055607158332693 0.2279869140193289 1.0 0.6672360566866387 16 Q9NPH0,Q9HBU6,Q9HCL2 3 +Steroid biosynthesis 0.4324971697600451 1.1943350339290006 0.2323469385612915 1.0 0.6672360566866387 20 P48449,Q16850,Q15125,Q15800,Q15392,Q14739 6 +Neurogenesis 0.4159854602152344 1.1031843429683257 0.2699471192333573 1.0 0.6964374789157718 51 P55209,P16949,Q9Y4G8,P31749,Q8IXJ6,Q9NQC3,Q8WWV3,Q8WUJ1,Q96EK5 9 +Electron transport 0.4172706354122744 1.0823161790528832 0.2791120593065606 1.0 0.6964374789157718 48 Q6DKK2,Q9UDW1,P22695,P00403,P03886,O43169,O14949,Q9H1E5,O43676,Q86Y39 10 +Glucose metabolism 0.5289545721368643 1.0762946251402998 0.2817955117000232 1.0 0.6964374789157718 9 P31751 1 +Sterol biosynthesis 0.4602966022692463 1.0395153939694513 0.2985651024568936 1.0 0.7138379918718941 15 Q16850,Q15125,Q15800,Q15392,Q14739 5 +Chemotaxis 0.6292953482490009 1.0058920618542606 0.3144674952135338 1.0 0.731458245651723 4 P09429 1 +Cholesterol biosynthesis 0.4609252306424313 1.0004223138108366 0.3171061758605735 1.0 0.731458245651723 14 Q14739,Q15392,Q16850,Q15125 4 +Methionine biosynthesis 0.8286475288546924 0.941079370385917 0.3466641865210849 1.0 0.7591506869385783 2 Q9BV57 1 +Glycogen metabolism 0.5181915228773613 0.8991492644367265 0.3685731603745414 1.0 0.760456977126876 7 P31751 1 +Sensory transduction 0.5212436713672528 0.8650343659572424 0.3870199268166285 1.0 0.760456977126876 6 O60313,Q9H6K4 2 +Vision 0.5212436713672528 0.8650343659572424 0.3870199268166285 1.0 0.760456977126876 6 O60313,Q9H6K4 2 +Oogenesis 0.672291296625218 0.8574110559968925 0.3912177512386818 1.0 0.760456977126876 3 Q9H6S0,Q9Y5A9 2 +Meiosis 0.412737446953457 0.8247643304900507 0.409505401084165 1.0 0.7680820342884613 17 Q9H6S0,O94901,Q8IXJ6,Q8N2A8,Q9UQ84,Q9UQE7 6 +Differentiation 0.2997258659870256 0.8192188079506555 0.4126615860670162 1.0 0.7680820342884613 97 Q9Y4G8,P46379,Q96EK5,Q14997,Q9Y508,Q9H6S0,Q96TC7,Q07820,Q15019,O94901,O75312,Q9Y2W6,O96005,Q7L576,Q9BY67,Q13501,P49841,Q13555,Q9H2U1,Q08J23,Q9BXJ9,Q96PU8,P16220,P16949,Q8IXJ6,Q8NB90,Q8N2A8,Q14141 28 +Complement pathway 0.7943178455164277 0.8142318811422028 0.4155121248073405 1.0 0.7680820342884613 2 P10909 1 +Protein transport 0.3887235222412726 0.811045797113959 0.4173393712318807 1.0 0.7680820342884613 274 O60830,Q13505,Q96P70,Q9NS69,Q99595,Q9HD26,P24390,Q5JRA6,Q9Y5X3,Q8N4H5,P0CG08,O00410,Q9UNH7,Q9Y4P1,P12270,O43731,Q5HYI7,O60826,Q9HD20,Q15629,Q9P2W9,Q9UID3,O14964,A0AVF1,O60763,Q96QK1,Q8TEX9,Q9Y2T2,Q9BVK6,Q15388,P49257,P50542,Q9H9H4,O75381,Q8NFH4,O43752,Q9Y3A6,Q92572,O15126,A6NIH7,Q9BTX1,Q99584,O60749,O00159,Q9H814,Q96C92,P35606,Q8TAG9,Q567U6,O43633,Q9Y5J7,Q9Y5J9,P41208,O95249,O14925,Q08379,Q8TD16,Q9H4A6,Q9C0E2,Q99567,Q8N1F7,Q03518,Q92973,Q4V328,Q9BRG1,O60220,Q96ED9,Q5VZ89,Q9H3S7,Q9NR31,O95721,Q15363,O95070,O43707,Q9UJY4,Q15437,Q15276,P49755,Q96D46,Q96A65,Q8IUD2,Q8WUX9,O15027,Q969Q5 84 +Biomineralization 0.6360918458229601 0.7232107063261135 0.4695504421493073 1.0 0.807616860067528 3 Q6P4Q7 1 +Ubiquinone biosynthesis 0.6261561614171637 0.6873097322577729 0.4918875672063318 1.0 0.8079962371638829 3 Q8NI60 1 +Phagocytosis 0.6092947313341138 0.6275117792023752 0.5303238173471199 1.0 0.8417066091839609 3 P50570 1 +Sodium transport 0.4393685835433478 0.5708047020992318 0.5681320352100192 1.0 0.846567929697002 8 P55011,Q96QD8,Q9Y6M7 3 +Fucose metabolism 0.7203314590115457 0.5586061871365009 0.5764305165316084 1.0 0.846567929697002 2 Q9Y2G5 1 +Adaptive immunity 0.3728920052636647 0.5571457723006948 0.5774278364407297 1.0 0.846567929697002 17 Q9NZ08,Q03518,Q6P179 3 +Phospholipid biosynthesis 0.3805744700684255 0.5335431260528823 0.5936576661568722 1.0 0.8533457763453335 15 Q9HCL2,Q9NPH2,Q96N66,Q9UG56,Q9HBU6,P35790 6 +Porphyrin biosynthesis 0.4400870086009275 0.4019292853829192 0.6877360694235595 1.0 0.9116756303914962 5 P06132 1 +Autophagy 0.3406518477529777 0.3983883088239492 0.6903439744583006 1.0 0.9116756303914962 34 Q9Y6I9,Q5MNZ6,P53365,Q13501,Q969Q5,Q8IXJ6,O95721,P09429,Q9UMX0,Q9Y4P1 10 +Symport 0.3735739624205247 0.3114206812131097 0.7554808337079957 1.0 0.967305996528144 9 Q96QD8,Q9Y6M7 2 +Wnt signaling pathway 0.324328536386367 0.3049220476901801 0.7604255232822403 1.0 0.967305996528144 29 Q8N163,P49841,P25054,Q9P1Z2,O14641,Q14696,Q9Y297,Q5T9L3 8 +Biological rhythms 0.3107217952705456 0.1536655157180138 0.8778734762453815 1.0 1.0 48 Q8N163,O00429,Q05086,Q9UNS1,P06493,Q03164,Q8WXF1,P23246,P16220,O75116,Q9Y297,Q15233,P43490,O15294 14 +Pyrimidine biosynthesis 0.3580382276568263 0.151811481141467 0.8793356264565833 1.0 1.0 5 Q9NRF8 1 +Sodium/potassium transport 0.4339232567472304 0.1487147639325831 0.8817787108564861 1.0 1.0 3 P05023 1 +Leukotriene biosynthesis 0.3749630068067575 0.0275638840345687 0.978009987078578 1.0 1.0 2 Q99735 1 +Prostaglandin biosynthesis 0.3696359869784059 0.0269419819549468 0.9785060089007936 1.0 1.0 2 Q9H7Z7 1 +Transport 0.3845616880931313 0.019510869734731 0.9844335658999748 1.0 1.0 530 P55011,Q70HW3,O60830,O95563,P31751,Q13505,P46379,Q96P70,Q9Y282,P03886,Q9NS69,O43681,Q99595,O43808,Q13190,Q9BQE5,Q12981,Q9HD26,P24390,P00846,O00461,Q5JRA6,Q9Y5X3,Q8N4H5,P0CG08,P05023,O75964,Q9UDW1,O00410,Q93050,Q9UNH7,O43676,P98194,Q9Y4P1,Q9H2D1,P12270,Q9Y487,O43731,Q9UN86,Q9H2U1,Q5HYI7,O43169,Q4KMQ2,P24539,Q15629,Q9HD20,O60826,Q9P2W9,Q99720,Q9UID3,O14964,O43674,A0AVF1,O60763,Q9BSK2,Q9UBX3,Q6P4A7,Q96QK1,Q8TEX9,Q9Y2T2,P22695,Q9BVK6,Q7L5D6,Q15388,Q8IXU6,O14949,Q9H1E5,P49257,P50542,Q9H9H4,Q9BPX6,O75381,Q8NFH4,O95202,P31749,O43752,Q9Y3A6,Q9Y6M7,Q9BQT8,Q92572,Q07955,P21796,O15126,A6NIH7,Q96CU9,Q9H3N1,Q9BTX1,Q99584,Q14203,O60749,O00159,Q9H814,Q96C92,Q96PU8,P84103,P35606,Q6DKK2,P16615,Q567U6,Q9C0H2,Q9NWR8,O43633,Q9Y5J7,Q9Y5J9,O95197,P30825,Q86Y39,P41208,O95249,O43772,O14925,Q08379,Q8TD16,Q9H4A6,Q9C0E2,Q99567,Q8N1F7,Q9Y6C9,Q03518,Q96S66,Q9Y6M1,P00403,O96000,Q92973,P45880,Q14849,Q4V328,Q6P4Q7,Q9BRG1,O60220,Q96QD8,Q96ED9,P42704,Q5VZ89,Q8NEW0,Q9H3S7,Q9NR31,O95721,Q13277,P56556,Q15363,P06576,O95070,O43707,Q8TB61,Q9UJY4,Q15437,Q15276,P49755,Q96D46,Q96A65,Q8IUD2,Q8WUX9,P49069,O15027,Q9Y5K8,Q5T1M5,Q969Q5 158 diff --git a/protein_atlas_biological_process/selections.json b/protein_atlas_biological_process/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..f76180516778ee83c5cdeaeb57da1f34171e93f3 --- /dev/null +++ b/protein_atlas_biological_process/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthesis", "Adaptive immunity", "Amino-acid biosynthesis", "Amino-acid transport", "Angiogenesis", "Antiport", "Antiviral defense", "Apoptosis", "Arginine metabolism", "Aromatic hydrocarbons catabolism", "Asparagine biosynthesis", "Autophagy", "B-cell activation", "Behavior", "Biological rhythms", "Biomineralization", "Branched-chain amino acid biosynthesis", "Branched-chain amino acid catabolism", "Calcium transport", "Carbohydrate metabolism", "Carnitine biosynthesis", "Catecholamine metabolism", "Cell adhesion", "Cell cycle", "Cell division", "Cell shape", "Chemotaxis", "Cholesterol biosynthesis", "Cholesterol metabolism", "Chromosome partition", "Cilium biogenesis/degradation", "Coenzyme A biosynthesis", "Collagen degradation", "Complement pathway", "Cysteine biosynthesis", "DNA condensation", "DNA damage", "DNA excision", "DNA recombination", "DNA repair", "DNA replication", "DNA synthesis", "Detoxification", "Differentiation", "ER-Golgi transport", "Electron transport", "Endocytosis", "Erythrocyte maturation", "Exocytosis", "Fatty acid biosynthesis", "Fatty acid metabolism", "Fertilization", "Fucose metabolism", "GMP biosynthesis", "GPI-anchor biosynthesis", "Galactose metabolism", "Gastrulation", "Gluconate utilization", "Gluconeogenesis", "Glucose metabolism", "Glutathione biosynthesis", "Glycogen biosynthesis", "Glycogen metabolism", "Glycolysis", "Glyoxylate bypass", "Growth arrest", "Growth regulation", "Hearing", "Heme biosynthesis", "Host-virus interaction", "Hydrogen ion transport", "Hypusine biosynthesis", "Immunity", "Inflammatory response", "Inhibition of host STAT1 by virus", "Inhibition of host STAT2 by virus", "Inhibition of host innate immune response by virus", "Inhibition of host interferon signaling pathway by virus", "Innate immunity", "Inositol biosynthesis", "Ion transport", "Isoprene biosynthesis", "Keratinization", "Leukotriene biosynthesis", "Lipid biosynthesis", "Lipid degradation", "Lipid metabolism", "Lipid transport", "Meiosis", "Melanin biosynthesis", "Methionine biosynthesis", "Methotrexate resistance", "Mitosis", "Molybdenum cofactor biosynthesis", "Myogenesis", "Necrosis", "Neurogenesis", "Neurotransmitter degradation", "Neurotransmitter transport", "Nonsense-mediated mRNA decay", "Notch signaling pathway", "Nucleotide biosynthesis", "Nucleotide metabolism", "One-carbon metabolism", "Oogenesis", "Osteogenesis", "Pentose shunt", "Peptide transport", "Peroxisome biogenesis", "Phagocytosis", "Phenylalanine catabolism", "Phospholipid biosynthesis", "Phospholipid metabolism", "Plasminogen activation", "Polyamine biosynthesis", "Porphyrin biosynthesis", "Potassium transport", "Proline biosynthesis", "Proline metabolism", "Prostaglandin biosynthesis", "Prostaglandin metabolism", "Protein biosynthesis", "Protein transport", "Purine biosynthesis", "Purine salvage", "Pyridine nucleotide biosynthesis", "Pyridoxine biosynthesis", "Pyrimidine biosynthesis", "RNA-mediated gene silencing", "Respiratory chain", "Ribosome biogenesis", "Sensory transduction", "Serine biosynthesis", "Sexual differentiation", "Sodium transport", "Sodium/potassium transport", "Spermatogenesis", "Spermidine biosynthesis", "Sphingolipid metabolism", "Steroid biosynthesis", "Steroid metabolism", "Sterol biosynthesis", "Sterol metabolism", "Stress response", "Sugar transport", "Symport", "Tetrahydrobiopterin biosynthesis", "Transcription", "Transcription regulation", "Transcription termination", "Translation regulation", "Translocation", "Transport", "Tricarboxylic acid cycle", "Tyrosine catabolism", "Ubiquinone biosynthesis", "Ubl conjugation pathway", "Unfolded protein response", "Urea cycle", "Viral RNA replication", "Viral immunoevasion", "Viral penetration into host nucleus", "Virus entry into host cell", "Vision", "Wnt signaling pathway", "Xylose metabolism", "Zinc transport", "mRNA capping", "mRNA processing", "mRNA splicing", "mRNA transport", "rRNA processing", "tRNA processing"], "available_proteins": ["AAAS", "AACS", "AAR2", "AARS", "AARS2", "AARSD1", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABHD12", "ABHD6", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN4", "ACTR3", "ADA", "ADAM17", "ADAR", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFDN", "AGL", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AKAP17A", "AKAP8", "AKAP8L", "AKT1", "AKT2", "ALCAM", "ALDH18A1", "ALDH3A2", "ALDH4A1", "ALDOA", "ALDOC", "ALKBH5", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APBB1", "APC", "APEX1", "API5", "APOBEC3C", "APOL2", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP2", "ARG2", "ARHGEF2", "ARID1A", "ARID2", "ARIH1", "ARL2", "ARL3", "ARL6IP1", "ARL8B", "ARMC10", "ARMT1", "ARVCF", "ASAH1", "ASCC2", "ASCC3", "ASNA1", "ASNS", "ATAD2", "ATAD5", "ATG4B", "ATG9A", "ATIC", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATRX", "AUP1", "AURKB", "BABAM1", "BABAM2", "BAG6", "BANF1", "BAX", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCL2L13", "BCLAF1", "BCOR", "BICD2", "BIRC6", "BLM", "BMS1", "BNIP1", "BOP1", "BPTF", "BRCA1", "BRD2", "BRD3", "BRD4", "BRD7", "BRD8", "BRIX1", "BSG", "BTF3", "BTRC", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C1D", "C1QBP", "C2CD2L", "C2CD5", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CAMK1", "CAMK2G", "CAMLG", "CAND1", "CAND2", "CANX", "CAPRIN1", "CARM1", "CARS", "CARS2", "CBL", "CBX2", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC22", "CCDC86", "CCDC93", "CCNA2", "CCNB1", "CCNB2", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC20", "CDC23", "CDC27", "CDC34", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC6", "CDC73", "CDCA2", "CDCA5", "CDCA7L", "CDCA8", "CDH2", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPV", "CEP250", "CEP55", "CERS1", "CERS2", "CETN2", "CFL1", "CGGBP1", "CHAF1A", "CHAF1B", "CHCHD3", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD8", "CHEK2", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHP1", "CHST14", "CHTF18", "CHTOP", "CIAPIN1", "CIRBP", "CISD2", "CKAP2", "CKAP5", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLIC1", "CLIC4", "CLINT1", "CLPTM1", "CLPTM1L", "CLSTN3", "CLTA", "CLTC", "CLU", "CMPK1", "CNNM3", "CNNM4", "CNOT1", "CNOT10", "CNOT11", "CNOT2", "CNOT7", "CNOT9", "COG3", "COG7", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS6", "COPS7A", "COPZ1", "COQ8A", "COQ9", "CORO7", "COX2", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CREB1", "CREG1", "CRNKL1", "CS", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CWC15", "CWC22", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DCAF1", "DCAF13", "DCAF7", "DCP1A", "DCP2", "DCPS", "DCTN1", "DCTN3", "DCUN1D1", "DCXR", "DDA1", "DDB1", "DDRGK1", "DDT", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX46", "DDX47", "DDX5", "DDX51", "DDX54", "DDX56", "DECR1", "DENND4C", "DENR", "DERL1", "DERL2", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DICER1", "DIDO1", "DIMT1", "DIS3", "DKC1", "DLAT", "DLG1", "DLST", "DMAP1", "DNAAF5", "DNAJA3", "DNAJB1", "DNAJB4", "DNAJC13", "DNAJC2", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DPF2", "DPYSL2", "DSC2", "DSC3", "DSG2", "DST", "DTYMK", "DUS3L", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECH1", "ECHS1", "ECI1", "ECSIT", "EDF1", "EDRF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EGFR", "EHD1", "EHHADH", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC4", "EMG1", "EML4", "ENO1", "ENO2", "ENPP1", "ENSA", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPN1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERO1A", "ERP44", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EYA4", "EZH2", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAH", "FAM120B", "FAM162A", "FAM208A", "FAM210B", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD5", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FIP1L1", "FKBP15", "FKBP8", "FLII", "FLNA", "FLNB", "FLOT2", "FMR1", "FNBP1L", "FOXK1", "FOXK2", "FOXRED1", "FTSJ3", "FUBP1", "FUBP3", "FXR1", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCC2", "GCFC2", "GCN1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGA2", "GGPS1", "GHITM", "GINS3", "GINS4", "GM2A", "GMPS", "GNAI2", "GNAI3", "GNL2", "GNL3L", "GNPDA1", "GOLGA2", "GOLIM4", "GOLPH3", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPHN", "GPI", "GPKOW", "GPR89B", "GRB2", "GRIPAP1", "GRSF1", "GRWD1", "GSK3B", "GSPT1", "GSS", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GYG1", "GYS1", "H2AFX", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAUS1", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HECTD1", "HECTD3", "HELLS", "HERC2", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HINT2", "HIRA", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCS1", "HMGXB4", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOOK2", "HOXD13", "HPRT1", "HPSE", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "ILF2", "ILF3", "ILVBL", "IMP3", "IMP4", "IMPDH2", "INA", "INCENP", "INTS13", "INTS3", "INTS7", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IRF2BP1", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "IVD", "IWS1", "JAGN1", "JMJD6", "JUP", "KARS", "KAT7", "KCTD5", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0391", "KIAA1468", "KIF11", "KIF18B", "KIF1B", "KIF20A", "KIF20B", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIFBP", "KIFC1", "KIN", "KLC1", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRR1", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDAH", "LDLR", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LPCAT1", "LPGAT1", "LRP1", "LRP2", "LRPPRC", "LRRC8C", "LRRFIP2", "LRSAM1", "LRWD1", "LSG1", "LSM14B", "LSM2", "LSM3", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LZTS2", "MACF1", "MAD2L1", "MAGED1", "MAGT1", "MANF", "MAP1S", "MAP2K4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCH5", "MARK2", "MARS", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBOAT7", "MCAM", "MCAT", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MEAF6", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED21", "MED23", "MED24", "MED25", "MED4", "MEN1", "MESD", "MFAP1", "MFSD10", "MFSD3", "MFSD5", "MGEA5", "MGME1", "MGST2", "MIA3", "MICU1", "MIF", "MINDY3", "MKI67", "MKRN2", "MLEC", "MMS19", "MMS22L", "MOB4", "MON2", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPDZ", "MPG", "MPHOSPH10", "MPHOSPH8", "MPP5", "MRC2", "MRE11", "MRGBP", "MRM3", "MRPL58", "MRPS27", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTFP1", "MTHFD1L", "MTHFD2", "MTIF2", "MTM1", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MTX3", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYH10", "MYH14", "MYH9", "MYO1C", "MYO1D", "MYO6", "NAA15", "NACC1", "NAE1", "NAMPT", "NAP1L1", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCBP1", "NCBP3", "NCK1", "NCK2", "NCKAP1", "NCOA5", "NCSTN", "ND1", "NDC1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF4", "NDUFB1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFC2", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4", "NEDD4L", "NEK9", "NELFA", "NELFCD", "NELFE", "NES", "NEU1", "NFRKB", "NFS1", "NHP2", "NIP7", "NIPBL", "NISCH", "NKRF", "NLE1", "NLRX1", "NMD3", "NME1", "NME2", "NME3", "NME7", "NOA1", "NOC2L", "NOL11", "NOL8", "NOL9", "NONO", "NOP14", "NOP2", "NOP53", "NOP56", "NOP58", "NOSIP", "NPC1", "NPC2", "NPLOC4", "NPM1", "NRP1", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NTHL1", "NUBP2", "NUCKS1", "NUDC", "NUDCD1", "NUDT21", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OCRL", "OGDH", "OGT", "OPA1", "OPA3", "ORC2", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD7B", "PA2G4", "PABPC1", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1IP1", "PAK2", "PAK4", "PANK4", "PAPOLA", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PAWR", "PAXBP1", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCDH19", "PCID2", "PCK2", "PCM1", "PCNA", 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setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Diabetes mellitus 1 10 2.3540479624304766 0.018570214818339 3.1966019417475726 10.315533980582524 0.6190680538080506 0.4730085508812801 1.8480344075927575 1.973723369210009 0.8597438282474712 0.3113207504672028 0.0823779870445007 0.01497108596825 0.0538434207197609 0.2450354162713742 0.5734195146997583 +Proto-oncogene 13 46 2.22185277381499 0.0262932568715241 10.220873786407768 42.230582524271846 0.352417122717188 0.6349839081636985 4.025676233803451 6.092151297173746 0.7870476016467428 0.3240376141995099 0.0099541344644992 0.1604114976239356 0.0142770645433407 0.0034311847643745 0.0138936167958461 diff --git a/protein_atlas_disease_involvement/metrics.json b/protein_atlas_disease_involvement/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..23b6c040fe4d9e08ff282f720f8c565b8bb29253 --- /dev/null +++ b/protein_atlas_disease_involvement/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3381, + "annotations_size": 114, + "title": "Average number of proteins per term", + "value": 23.37719298245614 +} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/paths.json b/protein_atlas_disease_involvement/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..985e42986c9588072e1d4e62e7868c5741733a5e --- /dev/null +++ b/protein_atlas_disease_involvement/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_disease_involvement/fragment/C317/C317_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/result.tsv b/protein_atlas_disease_involvement/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..8f12cb7d3a2ee954ff7febcc5bba79d3c4523b99 --- /dev/null +++ b/protein_atlas_disease_involvement/result.tsv @@ -0,0 +1,50 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Diabetes mellitus 0.7579675210821597 2.3540479624304766 0.018570214818339 0.8819807928754826 0.6284934960478539 10 P31751 1 +Proto-oncogene 0.5490986992151136 2.22185277381499 0.0262932568715241 0.9520473904333236 0.6284934960478539 46 Q92804,P06753,Q9NZQ3,P31749,P31751,Q5M775,Q06136,P35637,Q03164,Q01105,Q01844,Q8WY22,Q16204 13 +Ehlers-Danlos syndrome 0.9563578854895448 1.961674128603004 0.0498004357577073 0.997042734827891 0.6284934960478539 3 Q9NWM8 1 +Peroxisome biogenesis disorder 0.7885450799373357 1.8840893887866352 0.0595528853117395 0.9990877389488324 0.6284934960478539 5 O75381,P40855,P50542 3 +Zellweger syndrome 0.7885450799373357 1.8840893887866352 0.0595528853117395 0.9990877389488324 0.6284934960478539 5 O75381,P40855,P50542 3 +Cardiomyopathy 0.4957150965804563 1.657424451021008 0.0974336913859041 0.999991593418131 0.6284934960478539 28 P00846,O95677,O60313,Q9H9S5,P50402,P09493 6 +Albinism 0.783116996321652 1.6448999400351598 0.0999904473047741 0.999993916247004 0.6284934960478539 4 Q969F9 1 +Hermansky-Pudlak syndrome 0.783116996321652 1.6448999400351598 0.0999904473047741 0.999993916247004 0.6284934960478539 4 Q969F9 1 +Leber hereditary optic neuropathy 0.9908256880733944 1.5691819771561395 0.1166055424848497 0.9999992728359576 0.6284934960478539 2 P03886 1 +Deafness 0.4536140831150893 1.541639711668422 0.1231611697760319 0.999999688932788 0.6284934960478539 56 Q9NSV4,Q96D09,O60220,O95677,Q7Z406,Q9BV73,Q15067,Q9NR28,O60313,P35579,Q13868,Q9NWM8,Q9UG56,O95831 14 +Retinitis pigmentosa 0.5250884415966407 1.4579807542824292 0.1448458479070709 0.9999999820913604 0.6284934960478539 15 P00846,Q13868,Q8IY17 3 +Ciliopathy 0.5227102904114815 1.388310514532569 0.1650425118424658 0.9999999988258124 0.6284934960478539 14 Q7Z4L5,Q9UBB4,Q8WXW3,Q8NCM8,Q15058 5 +Primary mitochondrial disease 0.3386537753091251 1.372166631570677 0.1700115705642948 0.9999999994054172 0.6284934960478539 99 Q8NI60,Q70HW3,P22695,P03886,O60313,O14949,P42704,Q86Y39,P00846,P56556,O43676,P00403,O75208,P13073,O95831,Q9Y2R0,Q6DKK2,Q9UBX3,Q6P4A7,Q9H3H1 20 +Congenital muscular dystrophy 0.6247901766941697 1.348144674652782 0.1776118549638237 0.999999999791666 0.6284934960478539 6 Q9H9S5,Q9Y5P6 2 +Emery-Dreifuss muscular dystrophy 0.6522358600577243 1.2917806069975193 0.1964331331680147 0.9999999999851232 0.6284934960478539 5 P02545,Q8WXH0,P50402 3 +Rhizomelic chondrodysplasia punctata 0.7770710125751186 1.2630897058229733 0.2065569430927434 0.999999999996494 0.6284934960478539 3 O00116 1 +Cataract 0.4449840200143563 1.256213653218181 0.2090385179068161 0.999999999997547 0.6284934960478539 27 P48449,Q15125,P08670,Q15800,O00116,P35579,Q9UG56,Q9H6K4 8 +Dystroglycanopathy 0.6325301910679251 1.2048318881145863 0.2282682070592852 0.9999999999998516 0.6672455283271413 5 Q9H9S5 1 +FDA approved drug targets 0.339066555195617 1.1569015510890153 0.2473125849520399 0.9999999999999916 0.6876496264520133 123 P55011,Q16836,P62942,Q96QD8,Q13423,P03886,P28074,P20618,P21964,P12814,Q16739,Q16850,P05023,Q9NR33,P53396,P98194,P00813,Q99707,Q8N0U8,P00374,P38435,P49721,Q99720,P31350,Q9Y2I1,P16615,P49069 27 +Joubert syndrome 0.6063648248916546 1.0894673294077757 0.2759478543967275 1.0 0.7395319346043991 5 Q7Z4L5 1 +Long QT syndrome 0.8614974844628601 1.065568528310267 0.2866187322006936 1.0 0.7395319346043991 2 P0DP25 1 +Meckel syndrome 0.8511393903521773 1.026050126040142 0.3048679571732937 1.0 0.7395319346043991 2 Q7Z4L5 1 +Non-syndromic deafness 0.4305585759519105 1.0123267115633925 0.3113818672018522 1.0 0.7395319346043991 18 Q9NSV4,P35579,O95677,Q9NR28 4 +Ichthyosis 0.480817184609565 0.8912970203053664 0.3727698467993174 1.0 0.8172262025985038 10 P51648,Q15125 2 +Hirschsprung disease 0.8052678307191501 0.8542577617538085 0.3929621849227596 1.0 0.8227132139385136 2 Q96EK5 1 +Craniosynostosis 0.5508240278389211 0.847129324168968 0.3969230418124407 1.0 0.8227132139385136 5 P07237,P16435,Q08209 3 +Dwarfism 0.3841289507238837 0.8044314661786504 0.4211478346831057 1.0 0.8460017957059343 51 Q7RTS9,Q8WVQ1,Q96PZ0,Q15125,Q08209,Q32P28,O00116,O75718,Q13868,Q14739,Q9UG56,O95831,Q96HY6,Q8IY17 14 +Limb-girdle muscular dystrophy 0.4760462127369391 0.8012258687544587 0.4230008978529671 1.0 0.8460017957059343 9 Q9H9S5,Q9Y5P6,O14979 3 +Cone-rod dystrophy 0.6298817921622125 0.7007176054615757 0.4834792667680601 1.0 0.9077862154521242 3 Q9BV73 1 +Lissencephaly 0.4297928674430923 0.681180695717847 0.4957571613334348 1.0 0.9077862154521242 11 Q9H9S5,P07942 2 +Primary microcephaly 0.4135237794899712 0.6592446965239258 0.5097386492206366 1.0 0.9077862154521242 12 Q15058,Q66GS9,Q86XL3,Q8NFH4 4 +Neuropathy 0.3575179636304295 0.5752996466339663 0.5650886604649563 1.0 0.9077862154521242 53 Q9NSV4,P00846,P07196,Q14203,P05023,Q9H0B6,Q7Z406,O60333,Q15067,O95721,Q8TB36,P02545,Q96BR5,P50570,O95831,Q71SY5 16 +Congenital disorder of glycosylation 0.3650412320833707 0.5515733288233907 0.5812407138840521 1.0 0.9077862154521242 18 Q2TAA5,Q9BT22,Q9HC07,P46977,Q8N511 5 +Bardet-Biedl syndrome 0.5746060435924631 0.5098570599747827 0.6101516069048314 1.0 0.9077862154521242 3 Q2M1P5 1 +Schizophrenia 0.6883693400414365 0.4589382349717122 0.6462785208206316 1.0 0.9077862154521242 2 P21964 1 +Williams-Beuren syndrome 0.4113176282027077 0.4135936259441641 0.679171742098625 1.0 0.9077862154521242 7 Q96P11,Q9Y4P3 2 +Xeroderma pigmentosum 0.6673572062740502 0.398025495647147 0.6906113922802759 1.0 0.9077862154521242 2 P18074 1 +Cockayne syndrome 0.6673572062740502 0.398025495647147 0.6906113922802759 1.0 0.9077862154521242 2 P18074 1 +Charcot-Marie-Tooth disease 0.3310838320138792 0.3664059915503075 0.7140621495351971 1.0 0.9077862154521242 27 P07196,P05023,O60333,Q8TB36,P50570,O95831,Q71SY5 7 +Hereditary spastic paraplegia 0.350849997157855 0.3589869756132411 0.7196048327116475 1.0 0.9077862154521242 15 Q8IY17,O75298,Q8N0X7,Q9H0B6 4 +Premature ovarian failure 0.6498964190588983 0.3505503944891205 0.7259256770145648 1.0 0.9077862154521242 2 Q06787 1 +Progressive external ophthalmoplegia 0.454841575362735 0.3483085407111967 0.7276084804094594 1.0 0.9077862154521242 4 Q9BQP7,P12235,Q13472 3 +Intrahepatic cholestasis 0.6362829239419999 0.3156722376824398 0.7522513011073009 1.0 0.9077862154521242 2 Q9UDY2 1 +Amyotrophic lateral sclerosis 0.3412228590041468 0.2891069703980978 0.7724995196548436 1.0 0.9078860334087854 14 Q99720,P35637 2 +Osteogenesis imperfecta 0.3511380386730362 0.2210900080319982 0.8250223501985001 1.0 0.9405254792262902 9 Q96AY3,P07237,Q32P28,O75718 4 +Palmoplantar keratoderma 0.3438372890655715 0.1674507558708 0.8670153914860907 1.0 0.9736243576640464 7 Q06136 1 +Parkinsonism 0.3183535603660915 0.1068039407321633 0.914944521108517 1.0 0.9933683372035328 9 O43464,Q96QK1,Q14203 3 +Holoprosencephaly 0.4471737200355208 0.0471337739325088 0.9624066095352646 1.0 1.0 2 Q8N3U4 1 +Parkinson disease 0.2744254508953508 0.0037209205331256 0.99703114180541 1.0 1.0 7 O43464,Q96QK1 2 diff --git a/protein_atlas_disease_involvement/selections.json b/protein_atlas_disease_involvement/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..c71e41acc8411c8e64a5233a539fedd354b56d9c --- /dev/null +++ b/protein_atlas_disease_involvement/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Aicardi-Goutieres syndrome", "Albinism", "Allergen", "Alport syndrome", "Alzheimer disease", "Amelogenesis imperfecta", "Amyloidosis", "Amyotrophic lateral sclerosis", "Atrial fibrillation", "Autism", "Autism spectrum disorder", "Bardet-Biedl syndrome", "Bartter syndrome", "Cancer-related genes", "Cardiomyopathy", "Cataract", "Charcot-Marie-Tooth disease", "Ciliopathy", "Cockayne syndrome", "Cone-rod dystrophy", "Congenital adrenal hyperplasia", "Congenital disorder of glycosylation", "Congenital dyserythropoietic anemia", "Congenital hypothyroidism", "Congenital muscular dystrophy", "Congenital myasthenic syndrome", "Craniosynostosis", "Cushing syndrome", "Deafness", "Diabetes insipidus", "Diabetes mellitus", "Diamond-Blackfan anemia", "Disease variant", "Dwarfism", "Dyskeratosis congenita", "Dystonia", "Dystroglycanopathy", "Ectodermal dysplasia", "Ehlers-Danlos syndrome", "Elliptocytosis", "Emery-Dreifuss muscular dystrophy", "Epidermolysis bullosa", "Epilepsy", "FDA approved drug targets", "Fanconi anemia", "Gangliosidosis", "Gaucher disease", "Glaucoma", "Glutaricaciduria", "Glycogen storage disease", "Gout", "Hereditary hemolytic anemia", "Hereditary nonpolyposis colorectal cancer", "Hereditary spastic paraplegia", "Hermansky-Pudlak syndrome", "Hirschsprung disease", "Holoprosencephaly", "Hypogonadotropic hypogonadism", "Hypotrichosis", "Ichthyosis", "Intrahepatic cholestasis", "Joubert syndrome", "Kallmann syndrome", "Kartagener syndrome", "Leber congenital amaurosis", "Leber hereditary optic neuropathy", "Leigh syndrome", "Leukodystrophy", "Li-Fraumeni syndrome", "Limb-girdle muscular dystrophy", "Lissencephaly", "Long QT syndrome", "MELAS syndrome", "Maple syrup urine disease", "Meckel syndrome", "Mental retardation", "Metachromatic leukodystrophy", "Microphthalmia", "Mucopolysaccharidosis", "Myofibrillar myopathy", "Nemaline myopathy", "Nephronophthisis", "Neurodegeneration", "Neuronal ceroid lipofuscinosis", "Neuropathy", "Niemann-Pick disease", "Non-syndromic deafness", "Obesity", "Oncogene", "Osteogenesis imperfecta", "Osteopetrosis", "Palmoplantar keratoderma", "Parkinson disease", "Parkinsonism", "Peroxisome biogenesis disorder", "Pontocerebellar hypoplasia", "Premature ovarian failure", "Primary ciliary dyskinesia", "Primary hypomagnesemia", "Primary microcephaly", "Primary mitochondrial disease", "Progressive external ophthalmoplegia", "Proto-oncogene", "Pyropoikilocytosis", "Retinitis pigmentosa", "Rhizomelic chondrodysplasia punctata", "SCID", "Schizophrenia", "Spinocerebellar ataxia", "Systemic lupus erythematosus", "Tumor suppressor", "Williams-Beuren syndrome", "Xeroderma pigmentosum", "Zellweger syndrome"], "available_proteins": ["AAAS", "AARS", "AARS2", "ABAT", "ABCB1", "ABCB7", "ABCC1", "ABCD4", "ABHD12", "ACAA1", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOX1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ADA", "ADAM9", "ADAR", "ADD3", "ADK", "ADNP", "ADPRHL2", "ADSL", "AFDN", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AKAP12", "AKAP13", "AKAP9", "AKR1B1", "AKT1", "AKT2", "ALCAM", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG2", "AMPD2", "ANAPC1", "ANK3", "ANKLE2", "ANLN", "ANXA1", "ANXA11", "ANXA2", "ANXA7", "AP1B1", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "APC", "APEX1", "APOL2", "APP", "APRT", "ARCN1", "ARG2", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARIH1", "ARL2", "ARL3", "ARL6IP1", "ASAH1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD3A", "ATIC", "ATP11C", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP6", "ATP6AP1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATPAF2", "ATRX", "ATXN10", "AURKB", "B4GAT1", "BANF1", "BAX", "BAZ1B", "BCAP31", "BCAS3", "BCAT2", "BCLAF1", "BCOR", "BCS1L", "BICD2", "BIRC6", "BLM", "BLMH", "BMS1", "BPTF", "BRCA1", "BRD3", "BRD4", "BRD7", "BRI3BP", "BUB1B", "BUD23", "C19orf70", "C1QBP", "C3orf58", "CAD", "CADM1", "CALM3", "CALR", "CAMK2G", "CAMLG", "CANT1", "CANX", "CAPN1", "CARM1", "CARS", "CARS2", "CASK", "CAST", "CBL", "CBX2", "CCAR1", "CCAR2", "CCDC22", "CCDC47", "CCDC6", "CCDC8", "CCNA2", "CCNB1", "CCNB2", "CCT5", "CDC20", "CDC27", "CDC34", "CDC37", "CDC42", "CDC45", "CDC6", "CDC73", "CDH2", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDKAL1", "CEP135", "CEP250", "CEP55", "CERS1", "CFL2", "CHAMP1", "CHD1", "CHD3", "CHD4", "CHD8", "CHEK2", "CHMP1A", "CHMP2B", "CHMP4B", "CHP1", "CHST14", "CISD2", "CIZ1", "CKB", "CKMT1A*", "CLCC1", "CLCN7", "CLIC1", "CLN5", "CLPB", "CLPP", "CLPX", "CLTC", "CLU", "CNNM4", "CNOT1", "CNOT2", "COA3", "COA7", "COG7", "COLGALT1", "COMT", "COPA", "COPB2", "COQ8A", "COQ8B", "COQ9", "COX2", "COX4I1", "COX5A", "CPOX", "CPSF1", "CPT1A", "CPT2", "CREB1", "CRTAP", "CSDE1", "CSE1L", "CSNK2A2", "CSNK2B", "CSTB", "CTBP1", "CTCF", "CTH", "CTNNB1", "CTNNBL1", "CTNND1", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CWF19L1", "CYB5R3", "CYC1", "CYFIP2", "CYP51A1", "DAD1", "DARS", "DARS2", "DAXX", "DBN1", "DBT", "DCPS", "DCTN1", "DCUN1D1", "DDOST", "DDRGK1", "DDX10", "DDX3X", "DDX41", "DDX5", "DDX6", "DEK", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHTKD1", "DHX16", "DHX30", "DHX37", "DHX38", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIS3", "DKC1", "DLD", "DLST", "DNAAF5", "DNAJB1", "DNAJC13", "DNAJC2", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DPF2", "DPM1", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DYM", "DYNC1H1", "DYNC1I2", "DYNC2H1", "DYNLL1", "EARS2", "EBP", "ECE1", "ECHS1", "EDC3", "EEF1A2", "EEF2", "EFL1", "EFTUD2", "EGFR", "EHHADH", "EI24", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S2", "EIF3E", "EIF3F", "EIF3H", "EIF4A2", "EIF4A3", "EIF4E", "EIF4G1", "EIF4H", "EIF5A", "ELAC2", "ELP1", "ELP2", "ELP3", "EMC1", "EMD", "EMG1", "EML4", "ENO1", "ENO2", "ENPP1", "EPB41", "EPB41L3", "EPHA7", "EPHX1", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERC1", "ERCC2", "ERCC3", "ERGIC1", "ERLIN1", "ERLIN2", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXOSC2", "EXOSC3", "EXOSC9", "EYA4", "EZH2", "EZR", "FABP5", "FADS2", "FAF1", "FAH", "FAM120A", "FAM210B", "FAM3C", "FANCD2", "FANCI", "FAR1", "FARSB", "FASN", "FDPS", "FDXR", "FECH", "FEN1", "FGFR1OP", "FH", "FHL1", "FIP1L1", "FKBP10", "FKBP14", "FKBP1A", "FKBP5", "FKBP8", "FKRP", "FLAD1", "FLNA", "FLNB", "FLNC", "FMR1", "FOXRED1", "FSCN1", "FTO", "FUBP1", "FUCA1", "FUS", "G6PD", "GAA", "GALK1", "GALM", "GALNT2", "GANAB", "GAPDH", "GARS", "GART", "GATAD2B", "GATB", "GATC", "GBA", "GCDH", "GDAP1", "GDI1", "GEMIN4", "GFM1", "GFPT1", "GGCX", "GGPS1", "GIGYF2", "GLA", "GLB1", "GLDC", "GLMN", "GLO1", "GLRX5", "GLS", "GLUD1", "GM2A", "GMPPA", "GMPPB", "GMPS", "GNA13", "GNAI3", "GNE", "GNPAT", "GNS", "GOLGA5", "GOPC", "GOT1", "GOT2", "GPAA1", "GPHN", "GPI", "GPRASP2", "GRB2", "GSK3B", "GSR", "GSS", "GSTM3", "GSTZ1", "GTF2I", "GTPBP3", "GUF1", "GUSB", "GYG1", "GYS1", "H4C1*", "HADH", "HADHA", "HADHB", "HAX1", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HELLS", "HERC2", "HEXA", "HEXB", "HIBCH", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLCS", "HMBS", "HMGA1", "HMGB3", "HMGCL", "HMGXB4", "HMMR", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HOXD13", "HPRT1", "HPS3", "HPS6", "HSD17B10", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IFT27", "IFT52", "IGBP1", "IGF2R", "IGHMBP2", "ILF3", "ILK", "IMPAD1", "IMPDH2", "INF2", "INTS1", "INTS12", "IPO7", "IRF2BPL", "IRS4", "ITGB1", "ITM2B", "ITPA", "IVD", "JAGN1", "JUP", "KARS", "KDM1A", "KDM3B", "KDM5A", "KDSR", "KEAP1", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20B", "KIF22", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIF7", "KIFBP", "KLC2", "KMT2A", "KTN1", "L2HGDH", "LACTB", "LAMB1", "LAMC1", "LAMP2", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LGALS3", "LGALS3BP", "LGMN", "LIPA", "LMNA", "LMNB1", "LMNB2", "LONP1", "LRBA", "LRP1", "LRP2", "LRPPRC", "LRSAM1", "LSS", "LTA4H", "LYN", "LZTFL1", "MACF1", "MAD2L1", "MAGED1", "MAGED2", "MAGT1", "MAN2B1", "MAP1A", "MAP1B", "MAP2K1", "MAP2K4", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MARK3", "MARS", "MATR3", "MBD1", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM5", "MCM7", "MCTS1", "MDC1", "MDH1", "MDH2", "MECP2", "MED1", "MED12", "MED17", "MED23", "MED25", "MEN1", "MESD", "MGME1", "MICU1", "MIF", "MINPP1", "MIPEP", "MKI67", "MMAB", "MOGS", "MORC2", "MPI", "MRE11", "MRPL12", "MRPL3", "MRPL44", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS28", "MRPS34", "MRPS7", "MSH2", "MSH6", "MSMO1", "MSN", "MSTO1", "MTA1", "MTHFS", "MTM1", "MTMR2", "MTOR", "MTPAP", "MTR", "MUT", "MYH10", "MYH14", "MYH9", "MYO1E", "MYO6", "NAA10", "NAA15", "NACC1", "NAGLU", "NAMPT", "NANS", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPH", "NCKIPSD", "NCSTN", "ND1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA6", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB11", "NDUFB3", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NEDD4L", "NEFL", "NEK9", "NEU1", "NF2", "NFU1", "NHLRC2", "NHP2", "NIPBL", "NISCH", "NME1", "NME2", "NNT", "NONO", "NOP56", "NPC1", "NPC2", "NPM1", "NRP1", "NSD1", "NSD2", "NSDHL", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NTHL1", "NUBPL", "NUCB2", "NUDT1", "NUMA1", "NUP107", "NUP133", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP37", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXN", "OAT", "OCLN", "OCRL", "OGDH", "OGT", "OPA1", "OPA3", "OSGEP", "P3H1", "P4HA2", "P4HB", "PABPC1", "PABPN1", "PAF1", "PAFAH1B1", "PAFAH1B2", "PARK7", "PARN", "PARP1", "PARP2", "PBRM1", "PC", "PCBD1", "PCBP1", "PCCA", "PCCB", "PCDH19", "PCM1", "PCNA", "PDAP1", "PDCD4", "PDE4DIP", "PDE6D", "PDHA1", "PDHB", "PDK3", "PDP1", "PDSS2", "PDXK", "PEPD", "PEX14", "PEX16", "PEX19", "PEX3", "PEX5", "PFKM", "PFN1", "PGK1", "PGM1", "PGM3", "PHB", "PHF6", "PHF8", "PHGDH", "PHIP", "PI4KA", "PIBF1", "PICALM", "PIGK", "PIGL", "PIGS", "PIGT", "PIK3C2A", "PIN1", "PINX1", "PISD", "PKM", "PKP2", "PLAA", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNN", "PNP", "PNPLA6", "PNPO", "PNPT1", "POGZ", "POLA1", "POLD1", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR3A", "POMGNT2", "POP1", "POR", "PPA2", "PPIB", "PPIF", "PPOX", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R5D", "PPP3CA", "PPP5C", "PPP6C", "PPT1", "PRC1", "PRDX2", "PRDX4", "PRDX5", "PREPL", "PRKAA1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRPF3", "PRPF31", "PRPF4", "PRPF6", "PRPF8", "PSAP", "PSAT1", "PSIP1", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMD12", "PSMD4", "PTDSS1", "PTPN11", "PTPN23", "PTRH2", "PUF60", "PUM1", "PURA", "PUS1", "PUS7", "PYCR1", "PYCR2", "PYGL", "QARS", "QKI", "QRICH1", "QRSL1", "RAB10", "RAB11B", "RAB18", "RAB23", "RAB3GAP2", "RAB7A", "RAB8A", "RABEP1", "RAC1", "RAD21", "RAD23B", "RANBP2", "RANBP3", "RAP1GDS1", "RAPGEF2", "RARS", "RARS2", "RBM10", "RBM12", "RBM15", "RBM28", "RBM6", "RBMX", "RBPJ", "RDH11", "RDX", "RECQL4", "REL", "REPS1", "RFC1", "RFC2", "RFT1", "RHEB", "RHOA", "RINT1", "RNASEH2A", "RNASET2", "ROCK1", "ROCK2", "RP2", "RPA2", "RPL10", "RPL11", "RPL13", "RPL15", "RPL18", "RPL21", "RPL22", "RPL26", "RPL27", "RPL3", "RPL35", "RPL35A", "RPL5", "RPN1", "RPS10", "RPS15", "RPS15A", "RPS17", "RPS19", "RPS2", "RPS23", "RPS24", "RPS26", "RPS28", "RPS29", "RPS3", "RPS6KA1", "RPS6KA3", "RPS7", "RPSA", "RRM1", "RRM2", "RTN2", "RTN4IP1", "RXRB", "SAMHD1", "SAR1B", "SARS", "SART1", "SASS6", "SATB2", "SBDS", "SC5D", "SCARB2", "SCO1", "SCO2", "SCRIB", "SDHA", "SDHB", "SEC23A", "SEC23B", "SEC31A", "SEC61A1", "SEC63", "SEPT2", "SEPT9", "SERAC1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETDB1", "SF3B1", "SFPQ", "SFXN4", "SGPL1", "SH3GL1", "SH3PXD2B", "SHOC2", "SIGMAR1", "SIN3A", "SIRT2", "SKIV2L", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC38A2", "SLC3A2", "SLC5A6", "SMARCA4", "SMARCAD1", "SMARCB1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC3", "SMCHD1", "SMN1*", "SMPD4", "SNAP29", "SND1", "SNRNP200", "SNRPE", "SNX3", "SOAT1", "SOD2", "SON", "SORD", "SPART", "SPATA5", "SPECC1", "SPECC1L", "SPEN", "SPR", "SPTAN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRP54", "SRP72", "SRSF3", "SSB", "SSR4", "STAG1", "STAG2", "STAMBP", "STARD3", "STAT1", "STMN1", "STRAP", "STRN", "STT3A", "STT3B", "STUB1", "STX5", "SUCLA2", "SUCLG1", "SUZ12", "SV2A", "SYNE2", "TACO1", "TAF15", "TALDO1", "TAP1", "TARDBP", "TARS", "TARS2", "TBC1D4", "TBCD", "TBCE", "TBL2", "TCEA1", "TCF20", "TCOF1", "TDP2", "TECR", "TELO2", "TENM3", "TFAM", "TFG", "TFRC", "THG1L", "THOC2", "THOC6", "TIA1", "TIMM17A", "TIMM50", "TIMM8A", "TIMMDC1", "TJP2", "TK1", "TKT", "TMCO1", "TMEM165", "TMEM199", "TMEM38B", "TMEM43", "TMEM70", "TMF1", "TMLHE", "TMTC3", "TMX2", "TNPO3", "TOE1", "TOM1", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOR1A", "TOR1AIP1", "TP53", "TP53BP1", "TP53BP2", "TPD52", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPR", "TPX2", "TRAPPC11", "TRIM24", "TRIM25", "TRIM33", "TRIP12", "TRIP13", "TRIT1", "TRMT10C", "TRMU", "TRRAP", "TSC2", "TSFM", "TSG101", "TSR2", "TTC19", "TTC21B", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4B", "TUBB6", "TUBGCP2", "TUFM", "TWF1", "TWNK", "TXLNA", "TXNRD1", "TYMS", "U2AF1", "UBA1", "UBA5", "UBE2N", "UBE3A", "UBQLN4", "UBR5", "UBTF", "UFSP2", "UGCG", "UGDH", "UGP2", "UMPS", "UPF3B", "UQCC2", "UQCRB", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USMG5", "USP9X", "UTP4", "VAPB", "VARS1", "VARS2", "VCL", "VCP", "VIM", "VKORC1L1", "VPS13A", "VPS33A", "VPS35", "VPS45", "VPS4A", "VPS51", "VPS53", "VRK1", "WARS", "WARS2", "WASHC4", "WBP2", "WDR1", "WDR11", "WDR26", "WDR36", "WDR45B", "WDR5", "WDR73", "WFS1", "WNK1", "WRAP53", "XPNPEP3", "XPO1", "XRCC1", "XRCC5", "XRCC6", "XRN1", "YARS", "YARS2", "YBX1", "YEATS2", "YES1", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAZ", "ZC3H14", "ZCCHC8", "ZMPSTE24", "ZMYM2"], "leading_proteins": ["ACLY", "ACOX1", "ACTN1", "ADA", "AGPS", "AIFM1", "AKT1", "AKT2", "ALDH3A2", "ALG1", "ALG11", "ANKLE2", "ATP1A1", "ATP2A2", "ATP2C1", "ATP6", "ATXN10", "BRI3BP", "CALM3", "CAMLG", "CANT1", "CCDC6", "CEP135", "CEP250", "COA3", "COA7", "COMT", "COQ8A", "COQ9", "COX2", "COX4I1", "CRTAP", "CYP51A1", "DCTN1", "DDRGK1", "DHFR", "DIABLO", "DIAPH3", "DNM2", "DYM", "DYNC2H1", "EBP", "EMD", "ERCC2", "EWSR1", "EXOSC2", "EYA4", "FKBP10", "FKBP14", "FKBP1A", "FKRP", "FMR1", "FUS", "GDAP1", "GGCX", "GMPPB", "GPRASP2", "HADH", "HNRNPDL", "HPS3", "HTRA2", "KDSR", "KIF14", "KIF1B", "KIF7", "KIFBP", "KLC2", "KMT2A", "LAMB1", "LBR", "LMNA", "LRPPRC", "LSS", "MED25", "MGME1", "MSMO1", "MTR", "MYH14", "MYH9", "NCKIPSD", "ND1", "NDUFA11", "NDUFA6", "NDUFB3", "NEFL", "NISCH", "NNT", "NSUN5", "NUP37", "OPA1", "OPA3", "P3H1", "P4HB", "PEX14", "PEX19", "PEX5", "PIBF1", "PISD", "PNPLA6", "POLE4", "POR", "PPP3CA", "PSMB1", "PSMB2", "PSMB5", "PUS7", "RRM2", "RTN2", "SET", "SFXN4", "SIGMAR1", "SLC12A2", "SLC25A10", "SLC25A26", "SLC25A4", "SLC38A2", "SNAP29", "SPART", "SPECC1", "STAG2", "STT3A", "SYNE2", "TAF15", "TBL2", "TIMM8A", "TJP2", "TMEM165", "TMEM199", "TOP3A", "TPM1", "TPM3", "TRIT1", "TTC19", "TTC21B", "UGCG", "UQCRC2", "UQCRQ", "VIM", "VKORC1L1", "VPS35"]} \ No newline at end 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a/protein_atlas_molecular_function/consensus.joblib b/protein_atlas_molecular_function/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..9faa4e052ec4f7024683c7649180f5418d8e89aa --- /dev/null +++ b/protein_atlas_molecular_function/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3f059a5a87b60e2a9d421f54d13c58be399671ef1ca557009ed7ff6e07896015 +size 78057 diff --git a/protein_atlas_molecular_function/df_merge.tsv b/protein_atlas_molecular_function/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/protein_atlas_molecular_function/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/protein_atlas_molecular_function/metrics.json b/protein_atlas_molecular_function/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..4f3c01213e48eeb3ebe16e74cf7046228215f85e --- /dev/null +++ b/protein_atlas_molecular_function/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3381, + "annotations_size": 97, + "title": "Average number of proteins per term", + "value": 40.95876288659794 +} \ No newline at end of file diff --git a/protein_atlas_molecular_function/paths.json b/protein_atlas_molecular_function/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..e21a4bfa163ec569a4607b3676fb0ef1eae1c172 --- /dev/null +++ b/protein_atlas_molecular_function/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_molecular_function/fragment/C317/C317_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_molecular_function/result.tsv b/protein_atlas_molecular_function/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..cf90d3340895311a67c38a0eb28045b66aa8787d --- /dev/null +++ b/protein_atlas_molecular_function/result.tsv @@ -0,0 +1,32 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Monooxygenase 0.96714031971581 2.002811266237403 0.045197550139522 0.9887380941526795 0.4151639285862382 3 Q16850,Q9BU89 2 +Translocase 0.531131678208224 1.9333788979595483 0.0531895388460559 0.995016716097764 0.4151639285862382 24 P05023,Q13423,P00403,P03886,P16615,P06576,Q9HD20,Q03518 8 +Porin 0.8192732781313572 1.7929083967093338 0.0729875725068085 0.9993583488707556 0.4593009518260404 4 P21796 1 +Protease 0.3742116307430985 1.7758297552471085 0.0757609817445015 0.999520181482228 0.4593009518260404 86 P28072,Q9Y4E8,P67812,Q9H3G5,Q9Y4W6,Q96RU2,P28074,Q9H8M7,Q9NZ08,P55786,O43464,P52888,Q6P179,Q4J6C6,Q99436,Q5JRX3,O75844,Q96K76,P42785 19 +Threonine protease 0.8931320307874475 1.7179119606358662 0.0858126748678345 0.9998338830382498 0.4896370271870557 3 P28072,P28074 2 +Metalloprotease 0.4796926791388171 1.5302163346200208 0.1259631894373463 0.9999978699824223 0.5958774001373393 29 Q6P179,Q9NZ08,Q5JRX3,P55786,O75844,P52888 6 +Receptor 0.4574201256475209 1.3974289561653146 0.1622846166696594 0.9999999652975936 0.6360854508119153 43 Q99720,P10586,Q9Y5M8,O15173,Q9UBG0,O15031,O00264,O43731,Q9Y2I1,Q9NS69,P30825,Q14739,Q8WTV0,P24390 14 +Serine protease 0.5893405261223656 1.3919433635128808 0.1639395491783286 0.9999999713545956 0.6360854508119153 9 Q4J6C6 1 +Dioxygenase 0.4461233843096163 1.293287716146782 0.1959115675690195 0.999999999347666 0.6852573755185858 21 Q32P28,Q6PK18,O00625,Q8IVL6,Q9UPP1 5 +Chloride channel 0.6485168992376489 1.2753763381087706 0.2021760696373618 0.9999999996945188 0.6852573755185858 5 Q9C0H2,Q96S66 2 +Glycosyltransferase 0.4466919713204051 1.2677961379081428 0.2048707617529792 0.9999999997799816 0.6852573755185858 36 Q10472,Q68CQ7,Q13126,Q2TAA5,Q9BT22,Q9Y2G5,Q06203,Q16739,P43490,O15294 10 +Guanine-nucleotide releasing factor 0.4789444330977306 1.21609761537664 0.2239477388370991 0.9999999999791348 0.7240976889066206 16 P80303,Q14C86,Q9Y4G8 3 +Carboxypeptidase 0.5759376305638217 1.119533148591987 0.2629127573607386 0.999999999999859 0.7412266919950639 6 P42785 1 +Aminopeptidase 0.4913530677902688 1.0273513553262217 0.3042550483741038 0.9999999999999994 0.7412266919950639 11 P55786,Q9NZ08 2 +Developmental protein 0.3099641967887274 0.9990714661028448 0.3177600725237119 1.0 0.7412266919950639 94 P31751,Q9Y4G8,Q96EK5,Q14997,Q9NZN8,Q9Y508,Q07820,P31749,O15031,Q9UNS1,O96005,Q7L576,Q13555,P48681,Q9BXJ9,Q8NCM8,Q96PU8,Q5T9L3,O95677,P16949,Q9UEE9,O14641 22 +Heparin-binding 0.5041204991355057 0.9465501559784548 0.3438680529874007 1.0 0.7412266919950639 9 P10586,P51858 2 +Cytokine 0.5949477262165133 0.865238554650316 0.386907868140085 1.0 0.7638167286671292 4 P43490,P14174 2 +Myosin 0.4697833509049367 0.8317604306181794 0.4055441829375175 1.0 0.7638167286671292 10 P60660,P35579,P35580,Q7Z406 4 +Rotamase 0.3775739200669703 0.7447014523032403 0.4564522210164421 1.0 0.8003039223128704 23 Q9NWM8,O95302,Q9Y680 3 +Decarboxylase 0.4836450540712444 0.6943211266392175 0.487480844810565 1.0 0.8152696887349105 6 Q8NBZ7,P06132 2 +Chaperone 0.2941421073160566 0.6535775410766475 0.5133840175625743 1.0 0.8299708283928285 106 O75937,O60220,Q9Y5J7,Q9H2J4,P46379,Q9Y5J9,Q96A33,P10909,Q01105,O95429,O15212,O95456,Q9NPL8,Q9UHV9,Q96KC8,P07237,P78371,Q16543,O75880,Q99733,O60884,Q9Y5L4,Q8NB90,P78318,Q02790,Q14696,P49368 27 +Voltage-gated channel 0.4802901785142752 0.5540275479147662 0.5795599927759358 1.0 0.8680607532907059 5 P0CG08 1 +Ion channel 0.388344077710762 0.4597533448607166 0.6456932748125668 1.0 0.8947463950974139 11 Q9C0H2,Q96S66,P0CG08 3 +Motor protein 0.3419414450750049 0.4016422865768085 0.6879473043250455 1.0 0.8991132823857303 36 Q9H0B6,P33176,Q7Z406,O60333,Q2M1P5,O00159,P35580,P35579,Q8NCM8,P50570,Q15058,P60660 12 +Muscle protein 0.4109307771440437 0.3885773160466088 0.6975888497661262 1.0 0.8991132823857303 6 P67936,P09493 2 +Methyltransferase 0.3402494445421076 0.3830215230009333 0.7017038057271516 1.0 0.8991132823857303 45 Q96P11,Q8WTS6,Q99707,A6NJ78,Q03164,Q15047,P21964,O60725,Q08J23,O60678,Q86X55,Q9BV86,Q6P2P2 13 +Actin capping 0.3791232354046049 0.2873783719534441 0.7738226197593043 1.0 0.9477640265098508 7 Q13813,Q01082 2 +Calmodulin-binding 0.3057507283183021 0.1497159020125379 0.8809887616004428 1.0 0.9905841815712306 34 Q13813,P35611,Q08209,P35612,Q7Z406,O43815,Q13555,P35580,Q9UEY8,P35579,P32929,Q01844,Q01082 13 +GTPase activation 0.2921143763571711 0.1098034295221392 0.9125652711284782 1.0 0.9905841815712306 27 Q9Y3P9,Q14C86,Q9Y4G8 3 +Thiol protease 0.2931809110625491 0.1015690773626772 0.9190987251691832 1.0 0.9905841815712306 29 Q96K76,Q9Y4E8,Q9H8M7 3 +Cyclin 0.2933688573120138 0.0232780043850806 0.981428516917612 1.0 1.0 3 O95067,P20248 2 diff --git a/protein_atlas_molecular_function/selections.json b/protein_atlas_molecular_function/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..1f9ce063e23eb90d803ff8b85bd2b7b2acf6cda3 --- /dev/null +++ b/protein_atlas_molecular_function/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin capping", "Actin-binding", "Activator", "Acyltransferase", "Allosteric enzyme", "Aminoacyl-tRNA synthetase", "Aminopeptidase", "Aminotransferase", "Antibiotic", "Antimicrobial", "Antioxidant", "Aspartyl protease", "Blood group antigen", "Calcium channel", "Calmodulin-binding", "Carboxypeptidase", "Chaperone", "Chloride channel", "Chromatin regulator", "Cyclin", "Cytokine", "DNA-binding", "DNA-directed DNA polymerase", "Decarboxylase", "Developmental protein", "Dioxygenase", "Dipeptidase", "Elongation factor", "Endonuclease", "Excision nuclease", "Exonuclease", "Fungicide", "GTPase activation", "Glycosidase", "Glycosyltransferase", "Growth factor", "Guanine-nucleotide releasing factor", "Helicase", "Heparin-binding", "Hormone", "Host cell receptor for virus entry", "Hydrolase", "IgE-binding protein", "Initiation factor", "Integrin", "Ion channel", "Isomerase", "Kinase", "Ligase", "Lyase", "Metalloenzyme inhibitor", "Metalloprotease", "Methyltransferase", "Mitogen", "Monooxygenase", "Motor protein", "Multifunctional enzyme", "Muscle protein", "Myosin", "Nuclease", "Nucleotidyltransferase", "Oxidoreductase", "Peroxidase", "Phospholipase A2 inhibitor", "Porin", "Potassium channel", "Prenyltransferase", "Protease", "Protease inhibitor", "Protein kinase inhibitor", "Protein phosphatase", "Protein phosphatase inhibitor", "Protein synthesis inhibitor", "RNA-binding", "Receptor", "Repressor", "Ribonucleoprotein", "Ribosomal protein", "Rotamase", "Serine esterase", "Serine protease", "Serine protease inhibitor", "Serine/threonine-protein kinase", "Signal transduction inhibitor", "Thiol protease", "Thiol protease inhibitor", "Threonine protease", "Topoisomerase", "Transducer", "Transferase", "Translational shunt", "Translocase", "Tumor antigen", "Tyrosine-protein kinase", "Voltage-gated channel", "rRNA-binding", "tRNA-binding"], "available_proteins": ["AACS", "AARS", "AARS2", "AASDHPPT", "AASS", "ABAT", "ABCB1", "ABCC1", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD6", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR2", "ACTR3", "ADA", "ADAM17", "ADAM9", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFG3L2", "AGK", "AGL", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG2", "ALG5", "ALKBH5", "AMPD2", "ANKHD1", "ANKRD17", "ANLN", "ANO6", "ANP32B", "ANP32E", "ANXA1", "ANXA2", "APBB1", "APEH", "APEX1", "APLP2", "APOBEC3C", "APP", "APRT", "AQR", "ARFGAP1", "ARFGAP2", "ARG2", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID2", "ARIH1", "ARL8B", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASCC3", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD2", "ATG4B", "ATIC", "ATL2", "ATP11C", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5B", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "ATPAF2", "ATRX", "AURKB", "B4GAT1", "BABAM1", "BABAM2", "BAG4", "BAG5", "BAG6", "BANF1", "BAP18", "BAZ1B", "BAZ2A", "BCAT2", "BCLAF1", "BCOR", "BCS1L", "BDH2", "BIRC6", "BLM", "BLMH", "BLVRA", "BPNT1", "BPTF", "BRCA1", "BRD2", "BRD3", "BRD4", "BRD8", "BSG", "BTF3", "BTRC", "BUB1B", "BUD23", "BZW1", "BZW2", "C12orf43", "C1D", "CAD", "CADM1", "CALCOCO1", "CALD1", "CALR", "CAMK1", "CAMK2G", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN7", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CAST", "CBL", "CBR1", "CBX2", "CBX3", "CBX8", "CCAR1", "CCAR2", "CCDC47", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CDC34", "CDC37", "CDC42", "CDC5L", "CDCA7L", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CDKAL1", "CDKN2AIP", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPB", "CEP55", "CERS1", "CERS2", "CFDP1", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHCHD3", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD8", "CHEK2", "CHKA", "CHMP1A", "CHORDC1", "CHP1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIRBP", "CKB", "CKMT1A*", "CLCC1", "CLGN", "CLIC1", "CLIC4", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLU", "CLUH", "CMAS", "CMPK1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT2", "CNOT7", "CNOT9", "CNP", "COLEC12", "COLGALT1", "COMT", "COMTD1", "COPA", "COPS5", "COQ8A", "COQ8B", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX2", "COX4I1", "CPD", "CPNE1", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CREB1", "CRYZ", "CRYZL1", "CS", "CSDE1", "CSK", "CSNK1A1", "CSNK2A2", "CSTB", "CSTF2", "CTBP1", "CTBP2", "CTCF", "CTH", "CTNNB1", "CTPS1", "CTPS2", "CTSA", "CTSB", "CTSC", "CUL5", "CXorf57", "CYB5R3", "CYC1", "CYFIP1", "CYP20A1", "CYP51A1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCD", "DCP1A", "DCP2", "DCPS", "DCTPP1", "DCXR", "DDB1", "DDI2", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DECR1", "DEK", "DENND4C", "DENR", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS4", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DICER1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB4", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPM1", "DPP3", "DPYSL2", "DRG1", "DRG2", "DST", "DSTN", "DTYMK", "DUS3L", "DUSP12", "DUSP3", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC3", "EDF1", "EDRF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EFL1", "EGFR", "EHHADH", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMOD2", "ELP3", "EMD", "EMG1", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENPP1", "ENSA", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERCC2", "ERCC3", "ERCC6L", "ERMP1", "ERO1A", "ERP44", "ESD", "ESPL1", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EYA4", "EZH2", "F11R", "FADS2", "FAH", "FAHD1", "FAHD2A", "FAM120A", "FAM120B", "FAM208A", "FAM213A", "FAM3C", "FANCI", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD5", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FMR1", "FN3KRP", "FOXK1", "FOXK2", "FOXRED1", "FSCN1", "FSTL1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCDH", "GCN1", "GDI1", "GDI2", "GEMIN5", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GGPS1", "GLA", "GLB1", "GLB1L2", "GLDC", "GLO1", "GLS", "GLT8D1", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPB", "GMPS", "GNA13", "GNAI2", "GNAI3", "GNE", "GNG12", "GNG5", "GNPAT", "GNPDA1", "GNS", "GOT1", "GOT2", "GPAM", "GPAT4", "GPD2", "GPHN", "GPI", "GPKOW", "GPR89B", "GRHPR", "GRPEL1", "GRSF1", "GSK3B", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDLBP", "HEATR1", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HEXA", "HEXB", "HEXIM1", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIRA", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN3", "HMGXB4", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOXD13", "HP1BP3", "HPRT1", "HPSE", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HTATIP2", "HTATSF1", "HTRA2", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDI1", "IFIT5", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMP4", "IMPAD1", "IMPDH2", "INA", "INF2", "INTS11", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRS4", "ISYNA1", "ITCH", "ITGB1", "ITPA", "IVD", "JMJD6", "KARS", "KAT7", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0391", "KIF11", "KIF14", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KRR1", "KYAT3", "L2HGDH", "LACTB", "LAMP1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LBR", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD3", "LGALS3", "LGMN", "LIG1", "LIG3", "LIMA1", "LIPA", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LPGAT1", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRRC8C", "LRSAM1", "LRWD1", "LSG1", "LSM14B", "LSM2", "LSM3", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LUC7L3", "LYAR", "LYN", "LYPLA1", "MACF1", "MAGED1", "MAGED2", "MAN1A1", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP1S", "MAP2K1", "MAP2K4", "MAPK1", "MAPK14", "MAPK3", "MARC1", "MARCH5", "MARCKS", "MARCKSL1", "MARK2", "MARK3", "MARS", "MAT2A", "MATR3", "MBD1", "MBD3", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MEAF6", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED21", "MED23", "MED24", "MED25", "MED4", "MEN1", "MEPCE", "MESD", "METAP1", "METTL13", "METTL15", "MFN1", "MGEA5", "MGME1", "MGST1", "MGST2", "MGST3", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MKRN2", "MMAB", "MMS19", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOV10", "MPG", "MPHOSPH10", "MPHOSPH8", "MPI", "MPRIP", "MPST", "MRC2", "MRE11", "MRGBP", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL55", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MSH2", "MSH3", "MSH6", "MSMO1", "MTA1", "MTA2", "MTAP", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTM1", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTR", "MUT", "MYBBP1A", "MYCBP2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO6", "NAA10", "NAA15", "NAA40", "NAA50", "NACC1", "NADK2", "NAGLU", "NAMPT", "NANS", "NAP1L4", "NARS", "NAT10", "NAXE", "NCAM1", "NCBP3", "NCL", "NCOA5", "ND1", "NDUFAF2", "NDUFAF4", "NDUFAF7", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4", "NEDD4L", "NEK9", "NELFA", "NELFCD", "NELFE", "NES", "NEU1", "NFRKB", "NFS1", "NHP2", "NIFK", "NIP7", "NIPBL", "NISCH", "NKRF", "NKTR", "NLN", "NME1", "NME2", "NME3", "NME7", "NMT1", "NNT", "NOB1", "NOC2L", "NOL11", "NOL6", "NOL8", "NOL9", "NONO", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NOVA2", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NRDC", "NRP1", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDCD1", "NUDT1", "NUDT12", "NUDT16L1", "NUDT21", "NUDT5", "NUFIP2", "NUP153", "NUP98", "NXF1", "NXN", "OAT", "OCRL", "OGDH", "OGFOD3", "OGT", "OLA1", "OPA1", "ORC3", "OSGEP", "OTUB1", "OTUD7B", "OXSR1", "P3H1", "P3H3", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PAOX", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PAXBP1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PCYOX1", "PDCD4", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK3", "PDP1", "PDSS2", "PDXK", "PEBP1", "PECR", "PELP1", "PEPD", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB2", "PHC2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PI4K2A", "PI4KA", "PI4KB", "PIGK", "PIGL", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PLXNB2", "PMPCB", "PMS1", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POFUT1", "POFUT2", "POGZ", "POLA1", "POLD1", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR2B", "POLR2G", "POLR3A", "POLR3C", "POLR3F", "POLRMT", "POMGNT2", "PON2", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAT", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R8", "PPP1R9B", "PPP3CA", "PPP4C", "PPP5C", "PPP6C", "PPT1", "PPT2", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKACA", "PRKCD", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF31", "PRPF4B", "PRPF8", "PSAT1", "PSIP1", "PSMB5", "PSMB6", "PSMB7", "PSMD10", "PSMD14", "PSME4", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "PYM1", "QARS", "QKI", "QRSL1", "QSOX2", "RAB10", "RAB11B", "RAB18", "RAB1A", "RAB1B", "RAB23", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD50", "RALA", "RALY", "RANBP1", "RANBP2", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBFOX2", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "RECQL5", "REL", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC3", "RHOA", "RHOT1", "RHOT2", "RIC8A", "RICTOR", "RIDA", "RIOX1", "RIOX2", "RNASEH2A", "RNASET2", "RNF114", "RNF14", "RNF20", "RNF219", "RNF40", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP1", "RPF1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPP30", "RPP38", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RREB1", "RRM1", "RRM2", "RRP1B", "RRP8", "RRP9", "RSF1", "RTCA", "RTCB", "RTRAF", "RUVBL1", "RUVBL2", "RXRB", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAP130", "SAP18", "SAP30BP", "SARM1", "SARNP", "SARS", "SARS2", "SART3", "SATB2", "SC5D", "SCAF1", "SCAF4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SDHA", "SDHB", "SEC11A", "SEC61A1", "SEC63", "SENP3", "SEPHS1", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD7", "SETDB1", "SF1", "SF3B1", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SGPL1", "SGTA", "SHMT1", "SHMT2", "SHTN1", "SIGMAR1", "SIN3A", "SIN3B", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SLC1A5", "SLC27A2", "SLC27A4", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMCHD1", "SMN1*", "SMPD4", "SND1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPATA5", "SPCS2", "SPCS3", "SPEN", "SPOUT1", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SRCAP", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "STAMBP", "STAT1", "STAU1", "STAU2", "STK4", "STMN1", "STRBP", "STRN", "STT3A", "STT3B", "STUB1", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYNCRIP", "SYNE2", "TACO1", "TAF15", "TALDO1", "TAMM41", "TAOK3", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TCEA1", "TCERG1", "TCF20", "TCF25", "TCP1", "TDP2", "TDRKH", "TECR", "TERF2IP", "TFAM", "TFB1M", "TFCP2", "TFRC", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM13", "TIMM50", "TIMM8A", "TIMM8B", "TIMM9", "TIMMDC1", "TJP1", "TK1", "TKT", "TMCO1", "TMEM109", "TMEM38B", "TMF1", "TMLHE", "TMOD1", "TMOD3", "TMTC3", "TMX3", "TOMM22", "TOMM34", "TOMM40", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOPBP1", "TOR1A", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TRA2A", "TRA2B", "TRAP1", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIT1", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSC2", "TSFM", "TSN", "TSNAX", "TST", "TSTA3", "TTF2", "TTK", "TTYH3", "TUFM", "TWF1", "TWF2", "TWNK", "TXNDC12", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA6", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBLCP1", "UBP1", "UBR4", "UBR5", "UBTF", "UCHL5", "UCK2", "UFL1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "UMPS", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCRFS1", "UROD", "USP1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP28", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP3", "UTRN", "UXS1", "VARS1", "VARS2", "VASP", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIRMA", "VKORC1L1", "VPS4A", "VRK1", "VRK2", "WARS", "WARS2", "WASF2", "WDHD1", "WDR1", "WDR18", "WDR43", "WDR5", "WLS", "WNK1", "WNK3", "WRAP53", "WTAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPOT", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YBX1", "YEATS4", "YES1", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF2", "YTHDF3", "ZADH2", "ZC3H14", "ZC3HAV1", "ZCCHC11", "ZCCHC3", "ZCRB1", "ZFR", "ZMPSTE24", "ZNF207", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF638", "ZNF687", "ZRANB2"], "leading_proteins": ["ADD1", "ADD2", "ADD3", "AFG3L2", "AKT1", "AKT2", "ALG1", "ALG11", "ATP13A1", "ATP1A1", "ATP2A2", "ATP5B", "BAG4", "BAG6", "CAMK2G", "CARM1", "CCDC47", "CCNA2", "CCNB2", "CCT2", "CCT3", "CDC37", "CFDP1", "CLCC1", "CLPTM1", "CLU", "CNOT2", "COMT", "COX2", "CPVL", "CTH", "CYFIP1", "CYP51A1", "DNAJA2", "DNAJC1", "DNAJC8", "DNM2", "DOHH", "DVL2", "DYNC2H1", "ERAP1", "ERAP2", "EWSR1", "EYA4", "FKBP14", "FKBP4", "FKBP7", "FKBP9", "GALNT1", "GAPVD1", "GLT8D1", "GPR89B", "HDGF", "HTRA2", "ICMT", "IGBP1", "KDELR1", "KDELR3", "KIF14", "KIF1B", "KIF5B", "KIF7", "KIFBP", "KLC2", "KMT2A", "LBR", "MCL1", "MESD", "METTL15", "MIF", "MINDY3", "MRC2", "MTAP", "MTR", "MYH10", "MYH14", "MYH9", "MYL6", "MYO1C", "NAA15", "NAMPT", "NAP1L4", "ND1", "NES", "NISCH", "NNT", "NPEPPS", "NSUN2", "NSUN5", "NTMT1", "NUCB2", "OGFOD3", "OGT", "P3H1", "P3H3", "P4HB", "PDCL3", "PFDN2", "PFDN6", "PGRMC1", "PGRMC2", "PHF8", "PIR", "PITRM1", "PLXNB2", "POFUT2", "PPAT", "PPP3CA", "PRCP", "PREPL", "PRMT3", "PRMT9", "PSMB5", "PSMB6", "PSMB7", "PSME4", "PSMG1", "PTPRF", "QKI", "RABGAP1", "RAPGEF2", "RNF114", "SCARB1", "SCO1", "SEC11A", "SET", "SETD7", "SETDB1", "SIGMAR1", "SLC7A1", "SPATA5", "SPTAN1", "SPTBN1", "SRPRB", "STMN1", "STRN", "TAP1", "THOP1", "TIMELESS", "TIMM13", "TIMM8A", "TIMM8B", "TIMM9", "TIMMDC1", "TOMM22", "TPM1", "TPM4", "TTYH3", "UGCG", "UROD", "USP15", "USP28", "USP47", "UXS1", "VDAC1", "WLS", "ZMPSTE24"]} \ No newline at end of file diff --git a/protein_atlas_protein_class/advanced/idx2term.json b/protein_atlas_protein_class/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..fe6da5fa354db115fd9016d740cdb1a25a67ce5c --- /dev/null +++ b/protein_atlas_protein_class/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Predicted membrane proteins"} \ No newline at end of file diff --git a/protein_atlas_protein_class/advanced/plot_0.png b/protein_atlas_protein_class/advanced/plot_0.png new file 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sha256:32b430398799f4c0d5fbd73342e927ba77c1b8fa95da8ae64fb8a79e83c4d186 +size 144274 diff --git a/protein_atlas_protein_class/basic/plot_3.png b/protein_atlas_protein_class/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..68bb0e62f13d265ff2532724816771a8905686fe --- /dev/null +++ b/protein_atlas_protein_class/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:01f76fa3573dd101ceafbd38f31edf3cedb8778b0cf38a5f4c39ae419ca740d3 +size 139177 diff --git a/protein_atlas_protein_class/consensus.joblib b/protein_atlas_protein_class/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..02ff3b9b2a6c2dc774bf5df70496b04090d6e601 --- /dev/null +++ b/protein_atlas_protein_class/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:173e8a6a9b5203b56afad763ee5be42d6ced9c3eb6c44350502208644e7e07e3 +size 96326 diff --git a/protein_atlas_protein_class/df_merge.tsv b/protein_atlas_protein_class/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..3e6a22a4e0fceb87426e92089d2c23e1b8908f3a --- /dev/null +++ b/protein_atlas_protein_class/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Predicted membrane proteins 201 614 2.246692318831989 0.0246596974897084 204.61650485436897 563.8058252427185 3.080866334016093 0.3028099075873978 81.17076282318972 73.52280648113661 4.068861305085399 0.4187410497068249 3.5165645800992985e-11 1.5567484247366368e-06 4.235538702806526e-11 4.115166224022727e-12 3.101187624943494e-14 diff --git a/protein_atlas_protein_class/metrics.json b/protein_atlas_protein_class/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..fbefb55345be72913bf97e962ead1802e5caec1a --- /dev/null +++ b/protein_atlas_protein_class/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3381, + "annotations_size": 21, + "title": "Average number of proteins per term", + "value": 514.4285714285714 +} \ No newline at end of file diff --git a/protein_atlas_protein_class/paths.json b/protein_atlas_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..cf6a35286c296c803fd1c09efbd7c00d253e46e4 --- /dev/null +++ b/protein_atlas_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_protein_class/fragment/C317/C317_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_protein_class/result.tsv b/protein_atlas_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..55550cf7739c937586b009570530d40cd6624d5c --- /dev/null +++ b/protein_atlas_protein_class/result.tsv @@ -0,0 +1,7 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Predicted membrane proteins 0.5059830048527869 2.246692318831989 0.0246596974897084 0.4080574270529685 0.1294634118209692 614 P55011,Q9H6V9,Q7RTS9,Q70HW3,O60830,O95563,Q9Y287,Q9UBG0,Q13505,Q13423,Q9BT22,P30519,Q8N8Q8,Q9Y282,P03886,Q9NS69,Q15800,Q99595,O60725,O43808,Q13190,Q9BQE5,Q12981,Q16739,Q07065,Q9NX40,P43307,P24390,P00846,O00461,Q5JRA6,Q16850,Q07820,P0CG08,Q70UQ0,P05023,O75964,Q9UDW1,Q9NR77,P04843,Q9Y2W6,Q93050,Q969F9,Q15392,Q5VW38,P33908,Q8WY22,Q14BN4,O00264,O43676,P98194,Q86UE4,Q86XL3,Q9NPL8,P09601,Q96G23,Q9HCL2,Q8NCH0,Q8IY95,Q9Y487,Q8N0U8,O43731,O75845,Q9NR28,Q8N8L6,Q13555,O43169,Q9H2U1,Q8N511,Q15047,Q4KMQ2,P09493,Q15629,Q9HD20,Q9P2W9,Q5T9L3,Q99720,Q9Y2R0,Q567V2,Q06136,P46783,Q6UW02,Q9H9S5,Q9NX00,Q9UBX3,Q6P4A7,O15260,P57105,P67812,Q9NX62,Q9NQC3,Q8IXU6,Q9H1E5,O95470,P51648,Q9HBU6,Q9UKU0,O75381,O43752,Q9HC07,Q9Y6M7,Q96A26,O96005,O94919,Q9Y3P9,Q86YN1,Q8IYS2,Q6PK18,Q8WTV0,Q9BTX1,Q9HD45,Q9Y5M8,Q96KC8,Q05086,Q3SXM5,Q53S58,Q9H4I3,O95831,P38435,Q9NPR9,Q92804,P31350,P16615,O75844,P50402,Q8N2A8,Q9C0H2,Q9NWR8,Q92896,Q9BXK5,Q9BSJ5,O95197,Q96A33,Q969V3,Q8TBA6,P30825,P42858,Q9UBV2,Q8WXH0,Q86Y39,P10586,O95249,O43772,O14925,Q6UW68,Q15125,O15173,O60476,Q99567,Q8N1F7,P56378,Q9Y6C9,Q9H6K4,Q8IY17,Q03518,O43464,Q96S66,Q68CQ7,Q5BJF2,P00403,Q6ZRP7,Q9UDX5,P16435,P13073,P49815,O75298,Q10472,Q14849,Q6P4Q7,Q9GZY8,Q8IWA4,Q9H0W8,Q96PC5,P62942,Q9NZQ3,Q9Y4W6,Q96QD8,Q99805,Q6NUM9,Q5VZ89,Q8NEW0,Q96TC7,Q8NHH9,Q8TCT9,O15031,O60271,Q13277,Q15363,O95070,Q14739,Q96KA5,Q8TB61,Q2TAA5,Q86UP2,P49755,O75880,Q8WVQ1,P17152,O43657,P49069,Q9UG56 201 +Predicted secreted proteins 0.4121660094501035 1.360940833803226 0.1735323878698209 0.9817298287354218 0.4078502652346498 66 Q15165,Q9Y287,P80303,Q8WUJ1,P07942,Q8N128,P10909,Q9NZ08,Q8NDZ4,Q8WXW3,O94919,P43490,O60888,Q8IW92,P14174,Q9UMX5,Q6P179,O75718,Q9H9S5,P09429,P51858 21 +FDA approved drug targets 0.339066555195617 1.1569015510890153 0.2473125849520399 0.997436060646679 0.4721422076357125 123 P55011,Q16836,P62942,Q96QD8,Q13423,P03886,P28074,P20618,P21964,P12814,Q16739,Q16850,P05023,Q9NR33,P53396,P98194,P00813,Q99707,Q8N0U8,P00374,P38435,P49721,Q99720,P31350,Q9Y2I1,P16615,P49069 27 +RAS pathway related proteins 0.3573651117951305 0.5442841534003654 0.5862459499337367 0.9999999910548544 0.8207443299072313 30 P31749,P31751 2 +Candidate cardiovascular disease genes 0.382743012658928 0.486124175611264 0.6268791271746261 0.9999999989794356 0.8227788544166968 12 P10909,P09493 2 +Transporters 0.3728088425689249 0.0955126063824309 0.9239076775926944 1.0 1.0 389 P55011,Q70HW3,O95563,Q9Y287,Q96P70,Q8N8Q8,O43681,O43808,Q13190,Q16739,Q07065,Q9HD26,P24390,Q5JRA6,P05023,P04843,O00410,Q9NR77,Q93050,Q5VW38,Q8WY22,P98194,Q9Y4P1,Q9H2D1,Q8IY95,P12270,Q13555,Q8N511,Q4KMQ2,Q15629,Q9HD20,O60826,Q5T9L3,Q99720,O14681,P06493,P07602,Q9BSK2,Q9UBX3,Q92544,Q6P4A7,Q9BRK5,Q96QK1,O15260,Q8TEX9,P57105,Q9NPA0,Q8IXU6,P49257,P50570,Q9BPX6,O75381,Q8NFH4,O95202,P31749,O94901,O43752,Q9HC07,Q9Y6M7,Q9UHB9,O96005,Q9BQT8,Q8IYU8,Q16625,Q07021,O15126,Q9Y5Y5,Q8WTV0,Q9H3N1,Q9BTX1,O43865,O00159,Q96N66,Q9H814,Q9UH99,Q16543,P21281,P16615,O75844,Q567U6,Q9C0H2,Q9NWR8,P40855,Q96A33,Q969V3,O60313,Q8TBA6,P30825,Q9UBV2,O43772,Q6UW68,O00429,Q9C0E2,Q99567,Q8N1F7,Q9Y6C9,Q03518,Q96S66,Q5BJF2,P00403,P13073,Q92973,P45880,P35609,Q14849,Q6P4Q7,P54105,Q8IWA4,Q96PC5,P62942,Q96QD8,Q99805,Q8NEW0,Q8NHH9,P33176,Q13438,Q13277,Q15363,Q8TB61,P49755,Q96A65,P49069 122 diff --git a/protein_atlas_protein_class/selections.json b/protein_atlas_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..3502f0d3cc00d0b4f095772e0433149f031a3ec4 --- /dev/null +++ b/protein_atlas_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Blood group antigen proteins", "CD markers", "Cancer-related genes", "Candidate cardiovascular disease genes", "Citric acid cycle related proteins", "Disease related genes", "Enzymes", "FDA approved drug targets", "Human disease related genes", "Metabolic proteins", "Nuclear receptors", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Predicted secreted proteins", "RAS pathway related proteins", "RNA polymerase related proteins", "Ribosomal proteins", "Transcription factors", "Transporters"], "available_proteins": ["AAAS", "AACS", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABHD10", "ABHD12", "ABHD6", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ADA", "ADAM17", "ADAM9", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT1S1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG2", "ALG5", "ALKBH5", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APBB1", "APC", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOBEC3C", "APOL2", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID2", "ARIH1", "ARL1", "ARL10", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARL8B", "ARMC1", "ARMC10", "ARMC6", "ARMC8", "ARMCX3", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARVCF", "ASAH1", "ASCC2", "ASCC3", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG4B", "ATG9A", "ATIC", "ATL2", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPAF2", "ATPIF1", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKB", "B4GAT1", "BABAM1", "BABAM2", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAP18", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BDH2", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD2", "BRD3", "BRD4", "BRD7", "BRD8", "BRI3BP", "BRIX1", "BROX", "BSG", "BTF3", "BTRC", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C12orf73", "C14orf2", "C16orf58", "C17orf80", "C19orf25", "C19orf47", "C19orf70", "C1D", "C1QBP", "C1orf123", "C1orf35", "C2CD2L", "C2CD5", "C3orf58", "C5orf15", "C5orf24", "C5orf51", "C8orf59", "CAB39", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAMLG", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN7", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CAST", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC127", "CCDC134", "CCDC138", "CCDC22", "CCDC47", "CCDC58", "CCDC6", "CCDC8", "CCDC86", "CCDC93", "CCDC97", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC20", "CDC23", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC6", "CDC73", "CDCA2", "CDCA5", "CDCA7L", "CDCA8", "CDH2", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDKN2AIP", "CDR2L", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPV", "CEP135", "CEP170", "CEP250", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CGGBP1", "CGN", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHP1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSTN3", "CLTA", "CLTC", "CLU", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT10", "CNOT11", "CNOT2", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COG3", "COG7", "COIL", "COLEC12", "COLGALT1", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "COQ8B", "COQ9", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CREB1", "CREG1", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CRYZL1", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTH", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CUTA", "CWC15", "CWC22", "CWF19L1", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCD", "DCP1A", "DCP2", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DECR1", "DEK", "DENND4C", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS4", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB4", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPM1", "DPP3", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS3L", "DUSP12", "DUSP3", "DUT", "DVL2", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFHD1", "EFL1", "EFTUD2", "EGFR", "EHD1", "EHD4", "EHHADH", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENPP1", "ENSA", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPDR1", "EPHA7", "EPHX1", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EYA4", "EZH2", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAHD2A", "FAM114A2", "FAM120A", "FAM120B", "FAM129B", "FAM136A", "FAM162A", "FAM177A1", "FAM208A", "FAM210B", "FAM213A", "FAM3C", "FAM49B", "FAM8A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD5", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNBP1L", "FNBP4", "FNDC3A", "FOXK1", "FOXK2", "FOXRED1", "FSCN1", "FSTL1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GGH", "GGPS1", "GHDC", "GHITM", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA13", "GNAI2", "GNAI3", "GNB1L", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA4", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLPH3L", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPR107", "GPR108", "GPR89B", "GPRASP2", "GPS1", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS4", "HAUS5", "HAUS6", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDGFL2", "HDHD2", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HEXA", "HEXB", "HEXIM1", "HGH1", "HGS", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIRA", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN3", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK2", "HOXD13", "HP1BP3", "HPRT1", "HPS3", "HPS6", "HPSE", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBIP", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPAD1", "IMPDH2", "INA", "INCENP", "INF2", "INTS1", "INTS11", "INTS12", "INTS13", "INTS14", "INTS3", "INTS4", "INTS7", "INTS9", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRS4", "ISCU", "ISOC1", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITM2B", "ITM2C", "ITPA", "ITPRIP", "IVD", "IWS1", "JAGN1", "JMJD6", "JPT2", "JUP", "KARS", "KAT7", "KCTD12", "KCTD5", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1468", "KIAA2013", "KIF11", "KIF14", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KNOP1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAMTOR3", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LPGAT1", "LRBA", "LRCH2", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC57", "LRRC59", "LRRC8C", "LRRFIP2", "LRSAM1", "LRWD1", "LSG1", "LSM12", "LSM14B", "LSM2", "LSM3", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L", "LUC7L2", "LUC7L3", "LUZP1", "LYAR", "LYN", "LYPLA1", "LYRM2", "LZIC", "LZTFL1", "LZTS2", "MACF1", "MAD2L1", "MAGED1", "MAGED2", "MAGT1", "MAK16", "MAN1A1", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K4", "MAP4", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARCKSL1", "MARK2", "MARK3", "MARS", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBOAT7", "MCAM", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MEAF6", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED21", "MED23", "MED24", "MED25", "MED4", "MEN1", "MEPCE", "MESD", "METAP1", "METTL13", "METTL15", "MFAP1", "MFF", "MFN1", "MFSD10", "MFSD3", "MFSD5", "MGEA5", "MGME1", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MIF", "MINDY3", "MINPP1", "MIOS", "MIPEP", "MKI67", "MKRN2", "MLEC", "MMAB", "MMS19", "MMS22L", "MOB4", "MOGS", "MON2", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPDZ", "MPG", "MPHOSPH10", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRC2", "MRE11", "MRGBP", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL55", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTM1", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MTX3", "MUT", "MXRA7", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO6", "NAA10", "NAA15", "NAA40", "NAA50", "NACC1", "NADK2", "NAE1", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCBP1", "NCBP3", "NCDN", "NCK1", "NCK2", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "NDC1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFC2", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NEU1", "NF2", "NFRKB", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIPSNAP3A", "NISCH", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NME3", "NME7", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NRBP1", "NRDC", "NRP1", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDT1", "NUDT12", "NUDT16L1", "NUDT21", "NUDT5", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "OCRL", "ODR4", "OGDH", "OGFOD3", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "ORC5", "OS9", "OSBP", "OSBPL11", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD7B", "OXA1L", "OXSR1", "P3H1", "P3H3", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1IP1", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PAOX", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATJ", "PAWR", "PAXBP1", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH19", "PCID2", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE4DIP", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDP1", "PDPR", "PDS5A", "PDS5B", "PDSS2", "PDXK", "PDZD11", "PEBP1", "PECR", "PEF1", "PELP1", "PEPD", "PES1", "PEX14", "PEX16", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF14", "PHF3", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHRF1", "PI4K2A", "PI4KA", "PI4KB", "PIBF1", "PICALM", "PIGK", "PIGL", "PIGS", "PIGT", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PKP2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POFUT1", "POFUT2", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3F", "POLRMT", "POMGNT2", "PON2", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP1R9B", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PRAF2", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PWWP2A", "PXMP2", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "PYM1", "QARS", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABEP1", "RABGAP1", "RABGGTA", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBFOX2", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "RECQL5", "REEP3", "REEP4", "REEP5", "REL", "REPS1", "RER1", "RETREG2", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RICTOR", "RIDA", "RIF1", "RILPL1", "RINT1", "RIOX1", "RIOX2", "RMDN1", "RMDN3", "RNASEH2A", "RNASET2", "RNF114", "RNF14", "RNF20", "RNF219", "RNF40", "RNH1", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS19BP1", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSU1", "RTCA", "RTCB", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "RXRB", "S100A10", "S100A11", "S100A13", "SAAL1", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SASS6", "SATB2", "SBDS", "SBNO1", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDCCAG3", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT8", "SEPT9", "SERAC1", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHC1", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIKE1", "SIN3A", "SIN3B", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC30A7", "SLC35B2", "SLC35F2", "SLC38A2", "SLC3A2", "SLC4A1AP", "SLC4A7", "SLC5A6", "SLC6A15", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLMAP", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG8", "SMG9", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SNAP23", "SNAP29", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG5", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPECC1", "SPECC1L", "SPEN", "SPNS1", "SPOUT1", "SPPL2A", "SPR", "SPRYD4", "SPRYD7", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRBD1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAU1", "STAU2", "STIP1", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX3", "STX5", "STX6", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACO1", "TAF15", "TAF4", "TAF7", "TAGLN2", "TALDO1", "TAMM41", "TAOK3", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCF25", "TCOF1", "TCP1", "TDP2", "TDRKH", "TECR", "TELO2", "TENM3", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THADA", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM13", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TIMM9", "TIMMDC1", "TJP1", "TJP2", "TK1", "TKT", "TLN1", "TM9SF2", "TM9SF3", "TM9SF4", "TMA16", "TMCO1", "TMED1", "TMED10", "TMED2", "TMED5", "TMED9", "TMEM109", "TMEM11", "TMEM126A", "TMEM14C", "TMEM160", "TMEM165", "TMEM167A", "TMEM177", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM30A", "TMEM33", "TMEM38B", "TMEM43", "TMEM59", "TMEM70", "TMEM97", "TMF1", "TMLHE", "TMOD1", "TMOD3", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOM1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOPBP1", "TOR1A", "TOR1AIP1", "TOR1B", "TOX4", "TP53", "TP53BP1", "TP53BP2", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRIT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPYL1", "TSR1", "TSR2", "TST", "TSTA3", "TTC1", "TTC19", "TTC21B", "TTC26", "TTC27", "TTC37", "TTC38", "TTC4", "TTC5", "TTF2", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC16", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UACA", "UAP1", "UBA1", "UBA2", "UBA5", "UBA6", "UBAC1", "UBAP2", "UBAP2L", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBL5", "UBLCP1", "UBN2", "UBP1", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "UMPS", "UNC119B", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "URB2", "UROD", "USE1", "USMG5", "USO1", "USP1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP28", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "UXS1", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VASP", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VPS13A", "VPS18", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS51", "VPS52", "VPS53", "VRK1", "VRK2", "VTA1", "WAPL", "WARS", "WARS2", "WASF2", "WASHC4", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR36", "WDR41", "WDR43", "WDR45B", "WDR46", "WDR5", "WDR6", "WDR61", "WDR73", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIZ", "WLS", "WNK1", "WNK3", "WRAP53", "WRAP73", "WTAP", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YBX1", "YEATS2", "YEATS4", "YES1", "YIF1A", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM2", "ZMYM3", "ZMYM4", "ZMYND8", "ZNF207", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF622", "ZNF638", "ZNF687", "ZPR1", "ZRANB2", "ZW10", "ZYX", "ZZEF1"], "leading_proteins": ["ACLY", "ACSL6", "ACTN1", "ACTN2", "ADA", "AFG3L2", "AHCYL1", "AIFM1", "AKT1", "AKT2", "ALDH3A2", "ALG1", "ALG11", "ANKLE2", "ANO6", "APOL2", "ARL10", "ASNA1", "ATG4B", "ATL2", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2C1", "ATP5L", "ATP6", "ATP6V0A1", "ATP6V0A2", "ATP6V1B2", "BCL2L13", "BNIP1", "BRI3BP", "C14orf2", "C17orf80", "C1QBP", "C3orf58", "CAMK2G", "CAMLG", "CANT1", "CCDC22", "CCDC47", "CCDC93", "CDC37", "CDK1", "CERS2", "CHST14", "CKAP4", "CLCC1", "CLNS1A", "CLPTM1", "CLPTM1L", "CLU", "CNNM4", "COA3", "COMT", "COX18", "COX2", "COX4I1", "CRTAP", "CUTA", "CYB5B", "CYB5D2", "CYP20A1", "CYP51A1", "DENND4C", "DHCR24", "DHFR", "DHX36", "DIABLO", "DNAJC1", "DNM1L", "DNM2", "DOLPP1", "DYM", "EBP", "EI24", "EMC7", "EMD", "ENDOD1", "ERAP1", "ERAP2", "ERGIC3", "ETNK1", "EXOC4", "FAM162A", "FAM177A1", "FKBP1A", "FKRP", "GALNT1", "GGCX", "GLB1L2", "GLG1", "GLT8D1", "GOLGA5", "GOLIM4", "GOPC", "GOSR1", "GPAM", "GPR107", "GPR108", "GPR89B", "HADH", "HDGF", "HM13", "HMGB1", "HMOX1", "HMOX2", "HPS3", "HSDL1", "HTRA2", "HTT", "ICMT", "IKBIP", "IMPAD1", "IPO4", "IPO5", "IPO9", "ITM2B", "KDELR1", "KDELR3", "KDSR", "KIAA2013", "KIF5B", "KTN1", "LAMB1", "LBR", "LDAH", "LETM1", "LMAN1", "MAN1A1", "MAN1A2", "MBOAT7", "MCL1", "MCUB", "MFF", "MFN1", "MIA2", "MIA3", "MICU1", "MICU2", "MIF", "MPC2", "MPV17L2", "MRC2", "MSMO1", "MTCH2", "MTDH", "MTFP1", "MTR", "MTX1", "MYO1C", "NAMPT", "NCKIPSD", "NCLN", "ND1", "NDC1", "NDUFA11", "NDUFB3", "NENF", "NISCH", "NNT", "NUCB2", "NUP37", "NUP88", "NUP93", "OCIAD1", "OCLN", "OGFOD3", "OPA1", "OPA3", "OS9", "PEX14", "PEX16", "PEX19", "PGRMC1", "PGRMC2", "PHAX", "PIBF1", "PISD", "PLD6", "PLXNB2", "PNPLA6", "POLE4", "PON2", "POR", "PSAP", "PSMB1", "PSMB2", "PSMB5", "PTPRF", "PXMP2", "QSOX2", "RABGAP1", "RETSAT", "RMDN3", "RPN1", "RPS10", "RRM2", "RTN2", "RTN3", "RTN4", "SC5D", "SCAMP1", "SCARB1", "SCO1", "SDF4", "SEC11A", "SEL1L", "SETDB1", "SFXN4", "SGPL1", "SIGMAR1", "SLC12A2", "SLC25A10", "SLC25A17", "SLC25A20", "SLC25A21", "SLC25A26", "SLC25A32", "SLC25A33", "SLC30A7", "SLC35B2", "SLC35F2", "SLC38A2", "SLC4A7", "SLC7A1", "SLMAP", "SMG9", "SPAG9", "SRP68", "SRPRB", "SSR1", "STARD3", "STX18", "STX3", "STX5", "STX6", "SUN1", "SUN2", "SURF4", "SYNE2", "SYNJ2BP", "TAF15", "TAP1", "TDRKH", "TIMM17A", "TIMM17B", "TIMM23", "TIMMDC1", "TM9SF2", "TM9SF3", "TM9SF4", "TMED10", "TMED2", "TMEM11", "TMEM160", "TMEM165", "TMEM177", "TMEM192", "TMEM199", "TMEM205", "TMEM97", "TMX1", "TMX4", "TNPO1", 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b/protein_atlas_subcellular_location_all/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..12b057ebbef9a577dd3501f834fb95f47b224585 --- /dev/null +++ b/protein_atlas_subcellular_location_all/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a147abeeb81015bd2dd0a90268b01677e43e425459e17785ea80f35ed247b3f5 +size 76907 diff --git a/protein_atlas_subcellular_location_all/df_merge.tsv b/protein_atlas_subcellular_location_all/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..1b19be03bdf436afbc39dc5daab0fd484f3a6201 --- /dev/null +++ b/protein_atlas_subcellular_location_all/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Golgi apparatus 61 191 2.72596923613782 0.0064112973672985 46.45873786407767 176.03155339805826 1.3643789213018729 0.3972771337532677 14.511319530749702 26.453870355965975 1.6568954592349954 0.4161874156663988 0.0027081778610602 0.0937351458200969 0.0234679865121522 0.0006309647311718 2.650906732746374e-05 +Centriolar satellite 17 29 2.0745266423577498 0.0380304270526106 6.354368932038835 28.046116504854368 0.5330334825095895 0.5754639941794782 3.863025543447266 4.860211896177677 0.8074973811315178 0.3370904262689401 0.7628583107046957 1.0 0.6759110170121503 0.7780447555150953 0.3365758957729482 diff --git a/protein_atlas_subcellular_location_all/metrics.json b/protein_atlas_subcellular_location_all/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..77d5a252a2e0e272cbc0d9b500ab78fde037809b --- /dev/null +++ b/protein_atlas_subcellular_location_all/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3381, + "annotations_size": 33, + "title": "Average number of proteins per term", + "value": 158.0909090909091 +} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/paths.json b/protein_atlas_subcellular_location_all/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..2ebebb470b8de4ea17ce284d531b61ccdb256d1e --- /dev/null +++ b/protein_atlas_subcellular_location_all/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_subcellular_location_all/fragment/C317/C317_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/result.tsv b/protein_atlas_subcellular_location_all/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..559fdf440d7c00a2e6d89925161218ae2818bd38 --- /dev/null +++ b/protein_atlas_subcellular_location_all/result.tsv @@ -0,0 +1,16 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Golgi apparatus 0.4907045680372582 2.72596923613782 0.0064112973672985 0.1912407162700179 0.2115728131208507 191 Q7RTS9,Q5MNZ6,Q9H4A5,O00178,Q9Y287,Q9UNW9,P67812,Q9NX62,Q13439,Q8IXU6,Q8TBA6,P80303,Q13190,Q5VZ89,Q5VU43,Q8N4Q0,Q8NEW0,P24390,P10586,O00461,O43752,O60476,Q9HC07,Q08379,Q93050,Q8TD16,Q969F9,Q9H4A6,Q5VW38,P33908,O95070,Q9NWM8,Q8IYS2,Q9BV57,Q01082,O15212,O95456,P53365,Q9HD45,P09601,Q8NCH0,P25054,Q6ZRP7,Q5BKZ1,Q9UJY4,Q99996,P49755,Q9NPR9,Q8WVQ1,O00231,Q6P179,Q9UID3,O95302,P55327,Q9H9S5,O15027,A6NJ78,Q92896,Q9UG56,Q8NEY8,O15260 61 +Centriolar satellite 0.5494172555519978 2.0745266423577498 0.0380304270526106 0.7218211721336723 0.3602099752889443 29 Q13045,P11413,P33176,Q8NI35,O60271,Q15154,Q86UY6,Q86YS7,Q8WXW3,O43169,Q9P260,Q12873,Q53EZ4,Q00013,Q7Z4H7,P41208,Q03518 17 +Intermediate filaments 0.5305807130328618 1.9348233498973864 0.0530119767199941 0.8342826222528654 0.3602099752889443 31 P07197,O60884,P07196,Q8WXH0,Q9BWS9,P08670,Q3SXM5,O75718,Q86YN1,Q96K76 10 +Peroxisomes 0.5553443529641924 1.720118296775428 0.0854109404971079 0.9474638716102898 0.4026515766292232 16 O75381,P40855,Q15067,O00116,O15254 5 +Endoplasmic reticulum 0.4117992140281076 1.5606407039768375 0.1186085491429209 0.9844914386462172 0.4348980135240435 205 Q9H3G5,Q9BT22,Q9NQC3,O95197,Q15800,P84157,Q96A33,P30533,P21964,Q8WUJ1,Q12981,Q9Y680,O95470,P51648,P35790,P43307,Q16850,Q6UW68,P0CG08,Q70UQ0,P04843,Q15125,Q8NHH9,Q8TCT9,Q9NR31,Q13438,O96005,Q15293,Q14257,Q14BN4,O00264,Q96KA5,Q86UE4,Q8IY17,Q03518,P67809,Q96CN7,Q86XL3,Q96S66,Q96G23,Q96KC8,Q5BJF2,Q8N0U8,O43731,O43169,Q86UP2,Q9P2W9,Q96HY6,Q5T9L3,Q92791,Q14849,P50402,O43852,O15027,O15260,Q96PC5 56 +Lipid droplets 0.6102391849704424 1.5002967802311742 0.133537543123914 0.991174450720994 0.4406738923089164 9 Q01105 1 +Lysosomes 0.525467090528752 1.4054998095305786 0.1598727059143267 0.9968129556112424 0.4796181177429803 14 P09496,Q8IY95,O60749,O14964,Q9UNH7,Q96QK1,Q8WTV0 7 +Focal adhesion sites 0.3664892401354951 0.6203620494867846 0.5350194519256757 0.9999999999893988 0.8940104534710726 29 O60888,P49770,Q9Y487,Q9Y6M7,P12814,Q969Q5 6 +Centrosome 0.3422720738225055 0.607875842582349 0.5432698227580495 0.9999999999941284 0.8940104534710726 66 Q8WYA6,Q13561,P52789,Q7Z7E8,Q9BV73,O75419,Q9Y2W6,Q96DB5,P28074,O95684,Q99996,Q9BRT9,Q9BRR6,Q69YU5,Q9BSJ2 15 +Endosomes 0.404405216185932 0.6071090627035077 0.5437785361932286 0.9999999999943402 0.8940104534710726 12 Q8IY95,O60749,O14964,Q9UNH7,Q96QK1 5 +Microtubules 0.3586248667310197 0.5855530065017576 0.5581759360859986 0.9999999999980356 0.8940104534710726 53 Q13813,P55209,O60830,P31749,O60333,Q9Y2I1,O43768,P54105,Q6P2P2 9 +Actin filaments 0.3303951799727374 0.320199313646945 0.7488172434596647 1.0 0.9895856528637718 51 P17812,P12814,Q15019,Q6WCQ1,Q9NYL9,Q96DB5,O43707,Q9NVA1,Q9BTX1,Q05682,P09493,P67936,Q9HCD5,P35609,P06753,Q6P4Q7,P35580,Q6UW02,O75718,P35579,A6NJ78,Q9UPN3 22 +Midbody ring 0.3813084931219295 0.2797444870096393 0.7796735446805474 1.0 0.9895856528637718 6 Q06203 1 +Nuclear membrane 0.3031254242353751 0.1732051762613806 0.8624901550688553 1.0 1.0 63 Q9BTX1,Q96G23,P67812,O94919,Q9H1E5,P50402,Q8WXH0,Q9H8M7,O15260 9 +Kinetochore 0.5149452500739918 0.0983813674187779 0.9216294695438816 1.0 1.0 2 Q9BZD4 1 diff --git a/protein_atlas_subcellular_location_all/selections.json b/protein_atlas_subcellular_location_all/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..04a2326368826fb916cea1c9dd928d0d39077c68 --- /dev/null +++ b/protein_atlas_subcellular_location_all/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin filaments", "Cell Junctions", "Centriolar satellite", "Centrosome", "Cytokinetic bridge", "Cytoplasmic bodies", "Cytosol", "Endoplasmic reticulum", "Endosomes", "Focal adhesion sites", "Golgi apparatus", "Intermediate filaments", "Kinetochore", "Lipid droplets", "Lysosomes", "Microtubule ends", "Microtubules", "Midbody", "Midbody ring", "Mitochondria", "Mitotic chromosome", "Mitotic spindle", "Nuclear bodies", "Nuclear membrane", "Nuclear speckles", "Nucleoli", "Nucleoli fibrillar center", "Nucleoli rim", "Nucleoplasm", "Peroxisomes", "Plasma membrane", "Rods & Rings", "Vesicles"], "available_proteins": ["AAAS", "AACS", "AAR2", "AARS", "AARS2", "AARSD1", "AASS", "AATF", "ABAT", "ABCB1", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABHD10", "ABHD6", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR6", "ADA", "ADAM17", "ADAM9", "ADAR", "ADD1", "ADD2", "ADD3", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT1S1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG2", "ALG5", "ALKBH5", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP3B1", "AP3D1", "AP3S1", "APBB1", "APC", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOBEC3C", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARID1A", "ARID2", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARMC1", "ARMC10", "ARMC6", "ARMC8", "ARMCX3", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARVCF", "ASCC2", "ASCC3", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG4B", "ATG9A", "ATIC", "ATL2", "ATP13A1", "ATP1B3", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6V0A1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPAF2", "ATPIF1", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKB", "BABAM1", "BABAM2", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAP18", "BASP1", "BAZ1B", "BAZ2A", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCL2L13", "BCLAF1", "BCOR", "BDH2", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD2", "BRD3", "BRD4", "BRD7", "BRD8", "BRI3BP", "BRIX1", "BROX", "BSG", "BTF3", "BTRC", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C12orf73", "C14orf2", "C16orf58", "C17orf80", "C19orf25", "C19orf47", "C19orf70", "C1D", "C1QBP", "C1orf123", "C1orf35", "C2CD2L", "C2CD5", "C5orf15", "C5orf24", "C5orf51", "C8orf59", "CAB39", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2G", "CAMLG", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN7", "CAPNS1", "CAPRIN1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CAST", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC127", "CCDC138", "CCDC22", "CCDC47", "CCDC58", "CCDC6", "CCDC8", "CCDC86", "CCDC93", "CCDC97", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT6A", "CCT7", "CCT8", "CD109", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC20", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC6", "CDC73", "CDCA2", "CDCA5", "CDCA7L", "CDCA8", "CDH2", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK6", "CDK9", "CDKN2AIP", "CDR2L", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPV", "CEP170", "CEP250", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CGGBP1", "CGN", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD8", "CHEK2", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP5", "CHMP7", "CHORDC1", "CHP1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CIZ1", "CKAP2", "CKAP5", "CKB", "CLASP2", "CLCC1", "CLCN3", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLNS1A", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTC", "CLU", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT10", "CNOT11", "CNOT2", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COG3", "COG7", "COIL", "COLEC12", "COLGALT1", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COQ8A", "COQ8B", "COQ9", "CORO1B", "COTL1", "COX4I1", "COX5B", "COX6C", "COX7A2L", "CPD", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CREB1", "CREG1", "CRKL", "CRTAP", "CRYZ", "CRYZL1", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC22", "CWF19L1", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCP1A", "DCP2", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DECR1", "DEK", "DENND4C", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR7", "DHFR", "DHPS", "DHRS4", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB4", "DNAJC1", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPP3", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DTYMK", "DUS3L", "DUSP12", "DUSP3", "DUT", "DVL2", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFHD1", "EFL1", "EFTUD2", "EGFR", "EHD1", "EHD4", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOC", "ELP1", "ELP2", "ELP3", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENSA", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERH", "ERLIN1", "ERLIN2", "ERP29", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETFA", "ETFB", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC6", "EXOC7", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC7", "EXOSC9", "EYA4", "EZH2", "EZR", "F11R", "FABP5", "FAF1", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120A", "FAM120B", "FAM129B", "FAM136A", "FAM162A", "FAM177A1", "FAM208A", "FAM210B", "FAM3C", "FAM49B", "FAM8A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FBL", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP15", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNBP1L", "FNBP4", "FNDC3A", "FOXK1", "FOXK2", "FOXRED1", "FSCN1", "FSTL1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUS", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGA2", "GGPS1", "GHITM", "GIGYF2", "GINS3", "GINS4", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX5", "GLS", "GLT8D1", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPS", "GNA13", "GNAI2", "GNAI3", "GNB1L", "GNE", "GNG12", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GOLGA2", "GOLGA3", "GOLGA4", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLPH3L", "GOLT1B", "GOPC", "GORASP2", "GOT1", "GPAA1", "GPAM", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPR107", "GPR108", "GPR89B", "GPRASP2", "GPS1", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP3", "GTPBP4", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS6", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDGFL2", "HDHD2", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HELLS", "HELZ", "HERC2", "HEXA", "HEXIM1", "HGH1", "HGS", "HIBCH", "HINT2", "HINT3", "HIRA", "HIRIP3", "HIST1H1C", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCS1", "HMGN1", "HMGN3", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK2", "HOXD13", "HP1BP3", "HPRT1", "HPS3", "HPSE", "HS2ST1", "HSD17B11", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPH1", "HTATIP2", "HTATSF1", "HTRA2", "HTT", "HUWE1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IFIT5", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBIP", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPAD1", "IMPDH2", "INA", "INCENP", "INF2", "INTS1", "INTS11", "INTS12", "INTS13", "INTS14", "INTS3", "INTS4", "INTS7", "INTS9", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "ISCU", "ISOC1", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITM2B", "ITPA", "ITPRIP", "IVD", "IWS1", "JAGN1", "JMJD6", "JPT2", "JUP", "KARS", "KAT7", "KCTD12", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1468", "KIAA2013", "KIF11", "KIF14", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KNOP1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LACTB", "LAMC1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3", "LGMN", "LIG1", "LIG3", "LIMA1", "LIPA", "LMAN1", "LMF2", "LMNA", "LMNB1", "LMNB2", "LONP1", "LPCAT1", "LRBA", "LRCH2", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC57", "LRRC59", "LRRC8C", "LRRFIP2", "LRSAM1", "LRWD1", "LSG1", "LSM12", "LSM14B", "LSM2", "LSM3", "LSM7", "LSM8", "LTA4H", "LTN1", "LTV1", "LUC7L", "LUC7L2", "LUC7L3", "LUZP1", "LYAR", "LYN", "LYPLA1", "LYRM2", "LZIC", "LZTFL1", "LZTS2", "MACF1", "MAD2L1", "MAGED1", "MAGED2", "MAK16", "MAN1A1", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K4", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBOAT7", "MCAM", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MEAF6", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED21", "MED23", "MED25", "MED4", "MEN1", "MEPCE", "MESD", "METAP1", "METTL13", "METTL15", "MFAP1", "MFF", "MFN1", "MFSD10", "MFSD3", "MGEA5", "MGME1", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MIF", "MINDY3", "MIOS", "MIPEP", "MKI67", "MKRN2", "MMAB", "MMS19", "MMS22L", "MOGS", "MON2", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPG", "MPHOSPH10", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP5", "MPP7", "MPRIP", "MPST", "MRE11", "MRGBP", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL23", "MRPL28", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH2", "MTDH", "MTFP1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTM1", "MTMR2", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MTX3", "MUT", "MXRA7", "MYBBP1A", "MYCBP", "MYCBP2", "MYG1", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO6", "NAA10", "NAA15", "NAA40", "NAA50", "NACC1", "NADK2", "NAE1", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPH", "NCBP1", "NCBP3", "NCDN", "NCK1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "NDC1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF4", "NDUFB1", "NDUFB11", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFC2", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4", "NEFL", "NEFM", "NELFA", "NELFCD", "NELFE", "NEMF", "NES", "NEU1", "NF2", "NFRKB", "NFS1", "NFU1", "NHLRC2", "NIFK", "NIP7", "NIPBL", "NIPSNAP2", "NISCH", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NME3", "NME7", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NOVA2", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NRBP1", "NRDC", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSUN2", "NSUN5", "NT5C3A", "NT5DC1", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDT1", "NUDT16L1", "NUDT21", "NUDT5", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP188", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NUPL2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "OCRL", "ODR4", "OGDH", "OGFOD3", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "ORC5", "OS9", "OSBP", "OSBPL11", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD7B", "OXA1L", "OXSR1", "P3H1", "P3H3", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PAOX", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATJ", "PAWR", "PAXBP1", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCDH19", "PCID2", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNP", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE4DIP", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDP1", "PDPR", "PDS5A", "PDS5B", "PDSS2", "PDXK", "PEBP1", "PECR", "PEF1", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PGAM1", "PGAM5", "PGD", "PGLS", "PGM1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF14", "PHF3", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PI4KB", "PIBF1", "PICALM", "PIGL", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PIR", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PKP2", "PLA2G15", "PLAA", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLOD1", "PLOD2", "PLPBP", "PLRG1", "PLS3", "PMPCA", "PMPCB", "PMS1", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3F", "POLRMT", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAT", "PPHLN1", "PPIB", "PPID", "PPIE", "PPIF", "PPIG", "PPIL1", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6R3", "PPT1", "PPT2", "PRAF2", "PRC1", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PREP", "PRIM2", "PRKAA1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA4", "PSMA5", "PSMA6", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR2", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PWP1", "PWP2", "PWWP2A", "PYCR2", "PYCR3", "PYGB", "PYGL", "PYM1", "QARS", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB11B", "RAB13", "RAB14", "RAB1A", "RAB1B", "RAB23", "RAB24", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB9A", "RABEP1", "RABGAP1", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP1GDS1", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBFOX2", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCL1", "RCN1", "RCN2", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "RECQL5", "REEP4", "REEP5", "REPS1", "RER1", "RETREG2", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHOA", "RHOT2", "RIC8A", "RICTOR", "RIF1", "RILPL1", "RINT1", "RIOX1", "RIOX2", "RMDN1", "RMDN3", "RNASEH2A", "RNF114", "RNF14", "RNF20", "RNF219", "RNF40", "RNH1", "RNPEP", "RNPS1", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL32", "RPL34", "RPL35", "RPL36", "RPL36A", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS19BP1", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPSA", "RPTOR", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSU1", "RTCA", "RTCB", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "RXRB", "S100A10", "S100A11", "S100A13", "SAAL1", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SATB2", "SBDS", "SBNO1", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCML2", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT8", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHC1", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIKE1", "SIN3A", "SIN3B", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC30A7", "SLC35B2", "SLC35F2", "SLC38A2", "SLC3A2", "SLC4A1AP", "SLC4A7", "SLC5A6", "SLC6A15", "SLFN11", "SLIRP", "SLK", "SLMAP", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG8", "SMG9", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SNAP23", "SNAP29", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD2", "SNRPD3", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG5", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC24", "SPC25", "SPCS2", "SPECC1", "SPECC1L", "SPEN", "SPNS1", "SPPL2A", "SPR", "SPRYD4", "SPRYD7", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SQLE", "SQSTM1", "SRBD1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRPK1", "SRPK2", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAU1", "STAU2", "STIP1", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRIP1", "STRN", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX3", "STX5", "STX6", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACO1", "TAF15", "TAF4", "TAF7", "TAGLN2", "TALDO1", "TAMM41", "TAOK3", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TDP2", "TDRKH", "TECR", "TELO2", "TENM3", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THADA", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM13", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM9", "TIMMDC1", "TJP1", "TJP2", "TKT", "TLN1", "TM9SF3", "TMA16", "TMCO1", "TMED10", "TMED2", "TMEM109", "TMEM11", "TMEM126A", "TMEM165", "TMEM167A", "TMEM177", "TMEM192", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM70", "TMEM97", "TMF1", "TMLHE", "TMOD3", "TMX1", "TMX2", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOM1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1A", "TOR1AIP1", "TOR1B", "TOX4", "TP53", "TP53BP1", "TP53BP2", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRIT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPYL1", "TSR1", "TSR2", "TST", "TSTA3", "TTC1", "TTC19", "TTC21B", "TTC27", "TTC37", "TTC38", "TTC4", "TTC5", "TTF2", "TTK", "TTLL12", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4B", "TUBB6", "TUBGCP2", "TUFM", "TWF1", "TWF2", "TXLNA", "TXLNG", "TXNDC16", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "U2AF1", "U2AF2", "U2SURP", "UACA", "UAP1", "UBA1", "UBA2", "UBA5", "UBA6", "UBAC1", "UBAP2", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBLCP1", "UBN2", "UBP1", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UFSP2", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "UMPS", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCC2", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "URB2", "UROD", "USMG5", "USO1", "USP1", "USP10", "USP11", "USP14", "USP15", "USP28", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VASP", "VBP1", "VCL", "VCP", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS35", "VPS45", "VPS4A", "VPS51", "VPS53", "VRK1", "VRK2", "VTA1", "WAPL", "WARS", "WARS2", "WASF2", "WASHC4", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR36", "WDR41", "WDR45B", "WDR46", "WDR5", "WDR6", "WDR61", "WDR74", "WDR77", "WDR82", "WIZ", "WLS", "WNK1", "WNK3", "WRAP53", "WTAP", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YBX1", "YEATS2", "YEATS4", "YES1", "YIF1A", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF2", "YWHAB", "YWHAE", "YWHAG", "YWHAQ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZFR", "ZFYVE16", "ZMYM2", "ZMYM3", "ZMYM4", "ZMYND8", "ZNF207", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF622", "ZNF638", "ZNF687", "ZPR1", "ZRANB2", "ZW10", "ZYX", "ZZEF1"], "leading_proteins": ["ACOX1", "ACOX3", "ACTN1", "ACTN2", "ACTN4", "ADI1", "ADPGK", "AGPS", "AKAP9", "AKT1", "ALDH3A2", "ALG1", "ANKLE2", "APC", "ARFIP2", "ATL2", "ATP6V0A1", "ATP6V0A2", "BICD2", "BNIP1", "C12orf73", "C2CD5", "CALD1", "CALU", "CANT1", "CCDC47", "CDC45", "CEP250", "CEP55", "CERS2", "CETN2", "CHD3", "CHID1", "CHKA", "CHST14", "CLCC1", "CLNS1A", "CLPTM1", "CLPTM1L", "CLTA", "CNNM4", "COMT", "CPVL", "CRTAP", "CTNNBL1", "CTPS1", "CUTA", "CYB5B", "CYB5D2", "CYP20A1", "CYP51A1", "DCTN2", "DDRGK1", "DENND4C", "DNAJA2", "DNAJC1", "DOLPP1", "DYM", "EBP", "EIF2B2", "EMD", "ENDOD1", "ENSA", "ERAP2", "FGFR1OP", "FKBP14", "FKBP7", "FKBP9", "FKRP", "FLII", "G6PD", "GGA2", "GINS4", "GLG1", "GOLGA2", "GOLGA4", "GOLGA5", "GOLIM4", "GOLPH3", "GOLPH3L", "GPR107", "GPR108", "GPR89B", "GTPBP1", "HAUS6", "HGS", "HK2", "HM13", "HMOX1", "HPS3", "HSDL1", "IKBIP", "IMPAD1", "ISOC1", "ITM2B", "KDELR1", "KDELR3", "KIAA1468", "KIAA2013", "KIF1B", "KIF5B", "KTN1", "LRPAP1", "MACF1", "MAN1A1", "MAN1A2", "METTL15", "MIA2", "MINDY3", "MPP1", "MPRIP", "MSMO1", "MTDH", "MXRA7", "MYH10", "MYH9", "NAA40", "NAP1L1", "NCOA5", "NDC1", "NEFL", "NEFM", "NISCH", "NOVA2", "NUCB2", "NUF2", "OS9", "P3H4", "PATJ", "PCM1", "PDE4DIP", "PEX14", "PEX19", "PFDN6", "PGRMC1", "PIBF1", "PISD", "PNPLA6", "PPAT", "PPHLN1", "PRMT9", "PSMB5", "PSMD11", "PSMG1", "PTPRF", "QSOX2", "RAB24", "RCN1", "RCN2", "RMDN1", "RPN1", "RTN3", "RTN4", "SAR1A", "SCARB1", "SEC11A", "SEC16A", "SEPT2", "SET", "SGPL1", "SLC30A7", "SLC35F2", "SLC4A7", "SLMAP", "SNX2", "SNX6", "SPAG9", "SPTAN1", "SPTBN1", "SSR1", "STARD3", "STX18", "STX5", "STX6", "SURF4", "SYNE2", "TAP1", "TDRKH", "TIMM17B", "TM9SF3", "TMED10", "TMEM165", "TMEM192", "TMEM205", "TMEM97", "TMOD3", "TMX4", "TPD52", "TPM1", "TPM3", "TPM4", "TUBGCP2", "UBE2Q1", "UQCC1", "USP47", "VIM", "VKORC1L1", "VPS35", "VPS51", "WDR45B", "WLS", "YBX1", "YIF1A", "ZADH2", "ZNF326"]} \ No newline at end of file