diff --git a/interpro_active_site/advanced/idx2term.json b/interpro_active_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_active_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_active_site/basic/idx2term.json b/interpro_active_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_active_site/basic/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_active_site/consensus.joblib b/interpro_active_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..a1d4c3d412c87958d11dd3a06cda53158eab3200 --- /dev/null +++ b/interpro_active_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:716109e80c45454fbf5ca2e523608da21ca4b158c11fd8c045b052cff5858889 +size 72367 diff --git a/interpro_active_site/df_merge.tsv b/interpro_active_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_active_site/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_active_site/metrics.json b/interpro_active_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..d5f137e5bf0bb0d94ab38ed7e82c490e50cc692a --- /dev/null +++ b/interpro_active_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2772, + "annotations_size": 56, + "title": "Average number of proteins per term", + "value": 2.392857142857143 +} \ No newline at end of file diff --git a/interpro_active_site/paths.json b/interpro_active_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..770c03b2ae0bf30b82c2745960936f1bd3c532fa --- /dev/null +++ b/interpro_active_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C321/C321_val_log2fc"} \ No newline at end of file diff --git a/interpro_active_site/result.tsv b/interpro_active_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..3fb150eaba5f1b0682e9daca77aefea4aa4bbe46 --- /dev/null +++ b/interpro_active_site/result.tsv @@ -0,0 +1,6 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Malate dehydrogenase, active site [IPR001252] 0.6400722021660608 1.0861898390742553 0.2773950117733927 0.999999987455496 0.3788809916904877 2 P40925 1 +Peptidase family C14A, cysteine active site [IPR033139] 0.6417600462103835 0.5916315512063265 0.5540973412940866 1.0 0.6602010874993373 3 P42574 1 +Peptidase family C14A, His active site [IPR016129] 0.6417600462103835 0.5916315512063265 0.5540973412940866 1.0 0.6602010874993373 3 P42574 1 +Thiolase, active site [IPR020610] 0.3981854020771604 0.2211029516240134 0.8250122720691886 1.0 0.8884747545360492 5 P24752,P55084 2 +Ubiquitin-conjugating enzyme, active site [IPR023313] 0.3753907232019778 0.1710025547022331 0.8642217568231372 1.0 0.9131399694735036 5 Q16763 1 diff --git a/interpro_active_site/selections.json b/interpro_active_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..497df91dc71fea6bf50c1955fd2fbc2cf4ec5d69 --- /dev/null +++ b/interpro_active_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT1", "AKT2", "APEH", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "BLMH", "CAPN1", "CASP2", "CASP3", "CASP6", "CDK1", "CDK13", "CDK2", "CDK4", "CDK6", "CHEK2", "CHUK", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSB", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLUD1", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "IGF1R", "LDHA", "LDHB", "LONP1", "MAP2K1", "MAP2K2", "MAP3K7", "MAPK1", "MAPK3", "MARK2", "MDH1", "MDH2", "MTMR6", "NEK9", "NME1", "NME2", "PAK2", "PASK", "PBK", "PGAM1", "PKM", "PKMYT1", "PKN2", "PLK1", "PREP", "PRKAA1", "PRKACA", "PRPF4B", "PTK7", "PTPN1", "PTPN11", "RNASET2", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SUCLG1", "TALDO1", "TOP1", "TPI1", "TPP2", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UMPS", "UNG", "VRK1"], "leading_proteins": ["ACAT1", "CASP3", "HADHB", "MDH1", "UBE2S"]} \ No newline at end of file diff --git a/interpro_binding_site/advanced/idx2term.json b/interpro_binding_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_binding_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_binding_site/basic/idx2term.json b/interpro_binding_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..465c03bba181ece1b3cfc758ab37913f62157507 --- /dev/null +++ b/interpro_binding_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Protein kinase, ATP binding site [IPR017441]"} \ No newline at end of file diff --git a/interpro_binding_site/basic/plot_0.png b/interpro_binding_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..c86bd6b06e7f2027d381af8df389241db542f097 --- /dev/null +++ b/interpro_binding_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:90425c2f7749189d6d16457182df331ef61c50d8e233a565acaaa3637d83a423 +size 139958 diff --git a/interpro_binding_site/consensus.joblib b/interpro_binding_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..1aed231fb925f5f7d0754e28aeb8e4148436c808 --- /dev/null +++ b/interpro_binding_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d85363c709bc65c6a018a34558535d74c4e19bf5c94c25108222f0e5ef4019fe +size 64927 diff --git a/interpro_binding_site/df_merge.tsv b/interpro_binding_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_binding_site/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_binding_site/metrics.json b/interpro_binding_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..9b05bd746928d21a0711e4abdddc013124a1a6de --- /dev/null +++ b/interpro_binding_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2772, + "annotations_size": 28, + "title": "Average number of proteins per term", + "value": 4.285714285714286 +} \ No newline at end of file diff --git a/interpro_binding_site/paths.json b/interpro_binding_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..0e55ff680e4893aef067144a592fa7981da4babe --- /dev/null +++ b/interpro_binding_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C321/C321_val_log2fc"} \ No newline at end of file diff --git a/interpro_binding_site/result.tsv b/interpro_binding_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..6a090b596d60fa5b3de69165238802bc74c76ac1 --- /dev/null +++ b/interpro_binding_site/result.tsv @@ -0,0 +1,5 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Protein kinase, ATP binding site [IPR017441] 0.4029274129850068 1.149894884646663 0.2501871680183836 0.9996847316908832 0.4120729826185141 36 O43318,O95747,Q14004,P31749,Q7KZI7,P31751,Q99640,P36507,Q13043 9 +Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798] 0.6451263537906096 1.1093610108724934 0.2672744749855842 0.9998346679764416 0.4157602944220198 2 P34897 1 +PPM-type phosphatase, divalent cation binding [IPR000222] 0.7687100860770095 1.0315821668381644 0.3022678980642812 0.9999579966686186 0.4231750572899937 3 P49593 1 +Beta tubulin, autoregulation binding site [IPR013838] 0.3559066808906926 0.145837185258275 0.884049920122407 1.0 0.884049920122407 6 P68371,P04350,Q13885 3 diff --git a/interpro_binding_site/selections.json b/interpro_binding_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..20064eff160e381e534039f7f36b849160b5ce58 --- /dev/null +++ b/interpro_binding_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]"], "available_proteins": ["ACACA", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT1", "AKT2", "APEX1", "ASPM", "BPNT1", "CALU", "CAPN1", "CDK1", "CDK13", "CDK2", "CDK4", "CDK6", "CHUK", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DLAT", "DLST", "DST", "EHD1", "EIF2AK2", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "GCAT", "GOT1", "GOT2", "GPD2", "HK1", "HK2", "IDE", "IGF1R", "ILKAP", "IQGAP1", "LETM1", "MACF1", "MAP2K1", "MAP2K2", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MARK2", "MCCC1", "MICU1", "MYH10", "MYH9", "MYO1B", "MYO1C", "MYO1D", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXSR1", "PA2G4", "PAK2", "PASK", "PC", "PCCA", "PDCD6", "PEF1", "PGD", "PKMYT1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1F", "PPM1G", "PRKAA1", "PRKACA", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "RHOT1", "RHOT2", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "STK4", "TKT", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "UQCRC2", "VRK1"], "leading_proteins": ["AKT1", "AKT2", "CDK13", "MAP2K2", "MAP3K7", "MARK2", "OXSR1", "PKMYT1", "PPM1F", "SHMT2", "STK4", "TUBB2A", "TUBB4A", "TUBB4B"]} \ No newline at end of file diff --git a/interpro_conserved_site/advanced/idx2term.json b/interpro_conserved_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_conserved_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_conserved_site/basic/idx2term.json b/interpro_conserved_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..5b8066d37778c6b0c5c88ab0c3729c994e9fa7fc --- /dev/null +++ b/interpro_conserved_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "ABC transporter-like, conserved site [IPR017871]", "1": "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]"} \ No newline at end of file diff --git a/interpro_conserved_site/basic/plot_0.png b/interpro_conserved_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..6ddc74ace343139ccb01abcf426e562b5271d0fb --- /dev/null +++ b/interpro_conserved_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:eeb5e5e028df3608d02d1039bd5686641c2b98d08156833afaa37a82be36706a +size 137651 diff --git a/interpro_conserved_site/basic/plot_1.png b/interpro_conserved_site/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..b17a597606bded54f15beeb5b3d5322c90abf255 --- /dev/null +++ b/interpro_conserved_site/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:acbe71ef0e4b933aae0f94e358ced723fb87d097a4c1ee8022de963d65ff5559 +size 156103 diff --git a/interpro_conserved_site/consensus.joblib b/interpro_conserved_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..ac78e9b290d43b8c9bb4cbe7874095870115773c --- /dev/null +++ b/interpro_conserved_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8a261b921526f66b7ffb888c644a058b1540b3794833f05d4e1f6250262cb421 +size 113686 diff --git a/interpro_conserved_site/df_merge.tsv b/interpro_conserved_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_conserved_site/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_conserved_site/metrics.json b/interpro_conserved_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..635c899f60676c4e8fdbc4b3ea587e52f62ba0f7 --- /dev/null +++ b/interpro_conserved_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2772, + "annotations_size": 257, + "title": "Average number of proteins per term", + "value": 2.5525291828793772 +} \ No newline at end of file diff --git a/interpro_conserved_site/paths.json b/interpro_conserved_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..d0f5e84b2ef6042fb98399a8d6a9f13176755b81 --- /dev/null +++ b/interpro_conserved_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C321/C321_val_log2fc"} \ No newline at end of file diff --git a/interpro_conserved_site/result.tsv b/interpro_conserved_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..38b7c11142635bd4fdb541b5f432afda8a31595d --- /dev/null +++ b/interpro_conserved_site/result.tsv @@ -0,0 +1,32 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Haem oxygenase conserved site [IPR018207] 0.9610108303249096 2.5395644357449414 0.0110990598030693 0.943210639548242 0.0331681205742886 2 P30519 1 +ABC transporter-like, conserved site [IPR017871] 0.7042949086679792 1.7802510807136305 0.0750348791255306 0.999999998031132 0.1460906358731922 10 O75027,P33527,Q8NE71,O15439,Q9NRK6 5 +Ribosomal protein S5, N-terminal, conserved site [IPR018192] 0.7530685920577591 1.6087708690700924 0.107666452901828 0.999999999999807 0.1919935097612044 2 P82675 1 +Cyclic nucleotide-binding, conserved site [IPR018488] 0.6653429602888048 1.202451344936469 0.2291887062758046 1.0 0.3257010270244915 2 P10644 1 +Ubiquitin interacting motif [IPR003903] 0.8153200359373043 1.2019451755168595 0.2293847700055757 1.0 0.3257010270244915 3 Q92783 1 +Serpin, conserved site [IPR023795] 0.6628158844765306 1.1907854679883183 0.2337378151930698 1.0 0.3300583434319721 2 P50454 1 +Ribonuclease II/R, conserved site [IPR022966] 0.6523465703971079 1.1425399002050438 0.2532296707327797 1.0 0.353695790099589 2 Q8IYB7 1 +Thioredoxin, conserved site [IPR017937] 0.5181409439911643 0.9820752692777992 0.3260627680632963 1.0 0.4387336722108229 11 Q9H1E5 1 +Ubiquitin-activating enzyme E1, conserved site [IPR018074] 0.6101083032490929 0.9500290780315024 0.3420974777465431 1.0 0.4579117280253207 2 Q9UBT2 1 +ATPase, AAA-type, conserved site [IPR003960] 0.4451128909055655 0.911514602503796 0.3620242951625636 1.0 0.4820738023667298 16 Q9Y276,Q8NBU5,Q96TA2 3 +Phosphorylase pyridoxal-phosphate attachment site [IPR035090] 0.588447653429598 0.8533755857301134 0.3934510559916129 1.0 0.5055846069492226 2 P06737 1 +Kinesin motor domain, conserved site [IPR019821] 0.4898154818122675 0.7715143972685866 0.4404020920129725 1.0 0.5575533874252904 10 O00139,Q02241,Q99661,Q12756 4 +Actin, conserved site [IPR004001] 0.5588447653429549 0.7248093471845323 0.4685690006378076 1.0 0.5874255276288612 2 P61163 1 +DNA-directed DNA polymerase, family B, conserved site [IPR017964] 0.5534296028880812 0.701845211841229 0.482775699683486 1.0 0.602297838925514 2 P09884 1 +S100/Calbindin-D9k, conserved site [IPR001751] 0.5509025270758068 0.691195991431694 0.4894423826426699 1.0 0.6058122168780344 2 P31949 1 +Ribosomal protein L3, conserved site [IPR019926] 0.5490974729241822 0.6836165908114392 0.4942173054267214 1.0 0.6077217583476909 2 P09001 1 +DnaJ domain, conserved site [IPR018253] 0.4777571891341547 0.6550250033183741 0.5124516560355759 1.0 0.624170974413 9 Q96EY1 1 +Hexapeptide transferase, conserved site [IPR018357] 0.5097472924187668 0.524938537692611 0.5996259181655825 1.0 0.7134438007803459 2 Q96IJ6 1 +Intermediate filament protein, conserved site [IPR018039] 0.4573107518890721 0.520263008743467 0.6028802744750676 1.0 0.7140102789866009 8 P07196 1 +Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866] 0.6037320574317578 0.4737110856744929 0.6357059470139355 1.0 0.746011088504938 3 Q96I99 1 +GHMP kinase, ATP-binding, conserved site [IPR006203] 0.4693140794223762 0.378648865792321 0.7049486297706093 1.0 0.8088026689778866 2 Q03426 1 +Calreticulin/calnexin, conserved site [IPR018124] 0.5505182581020889 0.3267844777327577 0.7438309004399746 1.0 0.8347796568256483 3 O14967 1 +Heat shock protein Hsp90, conserved site [IPR019805] 0.5433563873416648 0.3089425964786453 0.7573651933842296 1.0 0.8462732813032477 3 P08238 1 +Purine phosphorylase, family 2, conserved site [IPR018099] 0.4281588447653369 0.2530490461269676 0.8002303128919976 1.0 0.8761336516004772 2 P00491 1 +Ribosomal protein L30, conserved site [IPR018038] 0.4162454873646136 0.221839297069003 0.8244389869061615 1.0 0.8940118971936012 2 P18124 1 +DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464] 0.3370773249303117 0.214628895223296 0.8300566637651585 1.0 0.89632169154473 11 Q9H2U1,Q86WJ1,Q7L2E3,Q7Z478,P18074 5 +Proteasome beta-type subunit, conserved site [IPR016050] 0.3549635184846298 0.1907056497148436 0.848756212099288 1.0 0.9088764437896542 8 P49721 1 +HMG box A DNA-binding domain, conserved site [IPR017967] 0.4658721560130068 0.1508762129099018 0.8800733650102817 1.0 0.9307223599087509 3 P09429,O15347 2 +Tubulin, conserved site [IPR017975] 0.3559066808906926 0.145837185258275 0.884049920122407 1.0 0.9307223599087509 6 P68371,P04350,Q13885 3 +Phosphatidylinositol 3/4-kinase, conserved site [IPR018936] 0.3936439147706707 0.0646998450709367 0.9484129861812453 1.0 0.9781646636001068 3 P42345,O00443 2 +Cullin, conserved site [IPR016157] 0.2580411998554394 0.028944899682249 0.9769085358404488 1.0 0.9923537300829854 5 Q13616,Q93034,Q13617,Q13618 4 diff --git a/interpro_conserved_site/selections.json b/interpro_conserved_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..5174246dff6c0d35a80dfd0e50a0d64aa6dd437b --- /dev/null +++ b/interpro_conserved_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Bromodomain, conserved site [IPR018359]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Heavy-metal-associated, conserved site [IPR017969]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Pyridoxamine 5'-phosphate oxidase, conserved site [IPR019740]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class II, conserved site [IPR002011]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB10", "ABCB7", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP3M1", "APEX1", "ARHGEF7", "ATAD1", "ATP5C1", "ATP5O", "ATP7B", "BAG6", "BAK1", "BAX", "BAZ1A", "BAZ1B", "BCAT2", "BCS1L", "BOP1", "BPNT1", "BRD2", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZB", "CASK", "CBR1", "CBX1", "CBX3", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD81", "CDKAL1", "CHAF1B", "CHD1", "CHD1L", "CHD4", "CLGN", "CMPK1", "CNDP2", "COPA", "COPZ1", "CORO1C", "CPOX", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX40", "DHX8", "DHX9", "DIDO1", "DIS3", "DIS3L2", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC9", "DNM1", "DNM1L", "DNM2", "DNMT1", "DRG1", "DRG2", "DSG2", "DST", "DTL", "DTYMK", "DYNLL1", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A3", "EIF4E", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPRS", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXC1", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLO1", "GMPPA", "GMPPB", "GNPDA1", "GNS", "GPI", "GRHPR", "GRWD1", "GSPT1", "GTF3C2", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IGF1R", "ILVBL", "IMPAD1", "IMPDH2", "INA", "IQGAP1", "IVD", "KDSR", "KIF11", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "LAMP1", "LARS", "LARS2", "LBR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MAPK3", "MARS", "MAT2A", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGST2", "MID1", "MIF", "MPI", "MPP2", "MPP6", "MPST", "MRPL3", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "MVK", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFV1", "NEFL", "NEFM", "NES", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD2", "NSF", "NSUN6", "NUBP2", "NUBPL", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF2", "PHF3", "PHGDH", "PHIP", "PIK3C2A", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PNP", "PNPLA6", "PNPO", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2E", "PPIB", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RASA1", "RCL1", "RDH13", "RDX", "RIDA", "RNF114", "RNF14", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RTN4IP1", "S100A10", "S100A11", "SART1", "SBDS", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC27A4", "SMARCA4", "SMS", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STRN", "STX10", "STX12", "STX17", "STX18", "STX4", "STX5", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE2", "TBL3", "TCP1", "TK1", "TLN1", "TMX1", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM21", "TRIM25", "TRIM27", "TRIM28", "TRIP13", "TRMT11", "TSFM", "TSPAN3", "TSPAN6", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UHRF1", "USP10", "USP11", "USP14", "USP19", "USP28", "USP33", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "WARS", "WDHD1", "WDR1", "WDR18", "WDR3", "WDR36", "WDR41", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2"], "leading_proteins": ["ABCB10", "ABCB7", "ABCC1", "ABCC4", "ABCF1", "ACTR1A", "ATAD1", "BCS1L", "CHD1L", "CLGN", "CUL1", "CUL2", "CUL3", "CUL5", "DHX29", "DHX30", "DHX36", "DIS3L2", "DNAJA3", "ERCC2", "GMPPA", "HMGB1", "HMGB3", "HMOX2", "HSP90AB1", "KIF1A", "KIF23", "KIF2A", "KIF2C", "MRPL3", "MRPS5", "MTOR", "MVK", "NEFL", "PIK3C2A", "PNP", "POLA1", "PRKAR1A", "PSMB2", "PYGL", "RPL7", "S100A11", "SERPINH1", "STAM", "SUCLG2", "TMX4", "TUBB2A", "TUBB4A", "TUBB4B", "UBA2", "YME1L1"]} \ No newline at end of file diff --git a/interpro_domain/advanced/idx2term.json b/interpro_domain/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..734b4abce37b547556178973ade879a858414968 --- /dev/null +++ b/interpro_domain/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "AAA+ ATPase domain [IPR003593]"} \ No newline at end of file diff --git a/interpro_domain/advanced/plot_0.png b/interpro_domain/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..82dfa6e0aca7a61caa5f92507e7eaf5a95553405 --- /dev/null +++ b/interpro_domain/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:59cd09e255b5326b4d64c8d6e0c76bd2f9922b749b1928155791df287f007239 +size 202550 diff --git a/interpro_domain/basic/idx2term.json b/interpro_domain/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..2e7598053e5dabf2b692d633bc33f3ef6ea34c3b --- /dev/null +++ b/interpro_domain/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "AAA+ ATPase domain [IPR003593]", "1": "ABC transporter-like, ATP-binding domain [IPR003439]", "2": "Linker histone H1/H5, domain H15 [IPR005818]", "3": "DEAD/DEAH box helicase domain [IPR011545]", "4": "GTP binding domain [IPR006073]", "5": "Protein kinase domain [IPR000719]", "6": "K Homology domain, type 1 [IPR004088]", "7": "Pleckstrin homology domain [IPR001849]", "8": "Helicase superfamily 1/2, ATP-binding domain [IPR014001]", "9": "K Homology domain [IPR004087]", "10": "Helicase, C-terminal [IPR001650]", "11": "SNF2, N-terminal [IPR000330]", "12": "EF-hand domain [IPR002048]", "13": "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) [IPR002314]", "14": "Cullin, N-terminal [IPR001373]"} \ No newline at end of file diff --git a/interpro_domain/basic/plot_0.png b/interpro_domain/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..3bdff089dd52090a42eb82503a3955e1d5d965e8 --- /dev/null +++ b/interpro_domain/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0edb5bc8cd63135da0ba603a59fb5a20a0918556da81c6a77fd6695425f138c2 +size 138666 diff --git a/interpro_domain/basic/plot_1.png b/interpro_domain/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..9d05bec004b62f333d5788981972da4380d27d21 --- /dev/null +++ b/interpro_domain/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c70a5165613f86c47975b3b1112eaa9adecc0a02136813f2553c65a2f729daca +size 138916 diff --git a/interpro_domain/basic/plot_10.png b/interpro_domain/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..816bb2fb7dbf380a08b30789f6c2a3a7ca06a418 --- /dev/null +++ b/interpro_domain/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:aad587e7a33ffcc551903a9864a5ad348ba5e9433a1e2aeaece7616fef034813 +size 145008 diff --git a/interpro_domain/basic/plot_11.png b/interpro_domain/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..6c33fd9d88cd135b81b350a9612859ebbc572515 --- /dev/null +++ b/interpro_domain/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6b567ad6579cfad1e8f00ebaab68e1af1ec4db61af9c1812572ae4e7c94e39e4 +size 135518 diff --git a/interpro_domain/basic/plot_12.png b/interpro_domain/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..567ceac03a8a72619426af428d4e137f2c76a66f --- /dev/null +++ b/interpro_domain/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d49428690ab18de2fd332943e571548be1654c8c3e1c13d91b81e5a0ec4b5c73 +size 139682 diff --git a/interpro_domain/basic/plot_13.png b/interpro_domain/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..7b8a09b1b3572900f69dea55e715a9ec683497f8 --- /dev/null +++ b/interpro_domain/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:038dca821f01fe67fa0b611a254eb5460b73739efcea81548cb71e2d836e0e58 +size 144177 diff --git a/interpro_domain/basic/plot_14.png b/interpro_domain/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..c6bc89708e640c739395e7b9bee73fbb9896be22 --- /dev/null +++ b/interpro_domain/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:12903b4a082e283458371285f3455f63f9748b45c1acf72b028962a526592ff4 +size 136523 diff --git a/interpro_domain/basic/plot_2.png b/interpro_domain/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..76b747385c096cbc8e49c1c1907f339c5d863aa2 --- /dev/null +++ b/interpro_domain/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:93f9d1937e5afe3dc5219d59eca755c3ce68330e97232dc6272a4d4256fdd0b1 +size 131199 diff --git a/interpro_domain/basic/plot_3.png b/interpro_domain/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..71fb4da189495f4592350b427537927e56591995 --- /dev/null +++ b/interpro_domain/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7bea04f26437b629bb132f5f3c46cbd99a9f81800501640b4d403fc221ed8726 +size 145459 diff --git a/interpro_domain/basic/plot_4.png b/interpro_domain/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..1b7bd34c76a6a64bc92d716b455c1ee0e6161f73 --- /dev/null +++ b/interpro_domain/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e1f846d2f876985cd4f72905fe7408fd3925bf0c791dd38216bb549049f2be47 +size 134122 diff --git a/interpro_domain/basic/plot_5.png b/interpro_domain/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..65350048be2393e2993bd06da461a8e9630a97ca --- /dev/null +++ b/interpro_domain/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:cc4e4d8c0c00d17441988541416eb21cae3dc1d8765bef031be8af90b5ae98e4 +size 137547 diff --git a/interpro_domain/basic/plot_6.png b/interpro_domain/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..2a98fa7b04794d73fd294388ca3818c11d9c78a9 --- /dev/null +++ b/interpro_domain/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fdd2a6541468808e7e754a8cfe07fbec8664595dbe4ed62ca9282101479014b7 +size 148608 diff --git a/interpro_domain/basic/plot_7.png b/interpro_domain/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..b027d4f168b2ce47b19a3bf61f0f2deb84cc0d8d --- /dev/null +++ b/interpro_domain/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:be0d029dad85952ec76015565c8be9deac44ad25c9318b8eeafeb1cfd1ce10ea +size 139567 diff --git a/interpro_domain/basic/plot_8.png b/interpro_domain/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..b4691ade69eec62942f16899f035dba735ad7054 --- /dev/null +++ b/interpro_domain/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4e28ffcddede360dff28a1ab9581c534509ab9ac171b6f59e4f0e642545a436e +size 152791 diff --git a/interpro_domain/basic/plot_9.png b/interpro_domain/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..f28ba7c1b60f235e21b2e449da53d96377bf40c8 --- /dev/null +++ b/interpro_domain/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:530498336da18b679bc46bf2c8acfeba11e2a86c9720730b84528f6563a93bfe +size 143463 diff --git a/interpro_domain/consensus.joblib b/interpro_domain/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..5546a009ca3ef5079369f6b9a3814db8e6c05368 --- /dev/null +++ b/interpro_domain/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:cf0384c92bc27a975991d5d1f9eb4371f3c07e894dc836a02cbc745d387f0a8c +size 595767 diff --git a/interpro_domain/df_merge.tsv b/interpro_domain/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..e32c1d7a759dec284ed71fd1b852d117db76c30b --- /dev/null +++ b/interpro_domain/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +AAA+ ATPase domain [IPR003593] 11 48 1.998367599311185 0.0456768216560432 15.315533980582524 53.91504854368932 -0.301482547874648 0.7101193728807252 8.066919832789411 5.471467628283315 0.5679404146055311 0.2838562818290112 1.0 0.0762203496734667 0.0602097240353476 0.0784860492089058 0.0062982805053085 diff --git a/interpro_domain/metrics.json b/interpro_domain/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..198ed6c663539b3ab50e031017b80b9e09b01f0d --- /dev/null +++ b/interpro_domain/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2772, + "annotations_size": 2334, + "title": "Average number of proteins per term", + "value": 2.0972579263067694 +} \ No newline at end of file diff --git a/interpro_domain/paths.json b/interpro_domain/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..83c3ea666c22ebc75026396a7288263913d117c4 --- /dev/null +++ b/interpro_domain/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C321/C321_val_log2fc"} \ No newline at end of file diff --git a/interpro_domain/result.tsv b/interpro_domain/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..275bdc1cba0c032cc0ab58fbae5606236123a707 --- /dev/null +++ b/interpro_domain/result.tsv @@ -0,0 +1,193 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Cytosolic fatty-acid binding [IPR000463] 0.9711191335740068 2.5829405517627073 0.0097962201343093 0.9999999998950048 0.0266795540180607 2 P09455 1 +Lipocalin/cytosolic fatty-acid binding domain [IPR000566] 0.9711191335740068 2.5829405517627073 0.0097962201343093 0.9999999998950048 0.0266795540180607 2 P09455 1 +Protein Kinase B, pleckstrin homology domain [IPR039026] 0.9259927797833928 2.3878488487723786 0.0169473102687207 1.0 0.0407783733682415 2 P31749 1 +Vicinal oxygen chelate (VOC) domain [IPR037523] 0.9180505415162444 2.353129013801502 0.0186161738159791 1.0 0.0431053072286659 2 Q9HC38 1 +NECAP, PHear domain [IPR012466] 0.9144404332129954 2.337309761523041 0.0194230833466231 1.0 0.0444010543888524 2 Q8NC96 1 +Kinesin-like [IPR022164] 0.8938628158844761 2.2466969584022136 0.0246594007761378 1.0 0.0532424064861292 2 Q9Y3P9 1 +GCF, C-terminal [IPR022783] 0.8924187725631765 2.240310129019991 0.0250707961231952 1.0 0.0537823880069281 2 P16383 1 +Acyl-CoA oxidase, C-terminal [IPR002655] 0.8826714801444038 2.1971041980219552 0.0280130053747811 1.0 0.0584292712642887 2 O15254 1 +SGNH hydrolase-type esterase domain [IPR013830] 0.8581227436823092 2.0875718456703427 0.0368364738857214 1.0 0.0719467197065052 2 Q15102 1 +Arfaptin homology (AH) domain [IPR010504] 0.8570397111913339 2.082716422831926 0.0372770795878114 1.0 0.0725039197982932 2 P53365 1 +AAA+ ATPase domain [IPR003593] 0.4795288827127181 1.9983675993111851 0.0456768216560432 1.0 0.0844678534812224 48 Q9NUQ8,Q9Y276,Q8NBU5,O75027,Q9NVI7,P08240,P33527,Q96TA2,Q8NE71,O15439,Q9NRK6 11 +Potassium channel tetramerisation-type BTB domain [IPR003131] 0.822382671480143 1.926364016351504 0.0540589372025688 1.0 0.0970565841775351 2 Q9NXV2 1 +Gamma tubulin complex component protein, N-terminal [IPR041470] 0.8212996389891682 1.9214486289068131 0.0546751728631615 1.0 0.0977868608908959 2 Q96CW5 1 +Gamma tubulin complex component, C-terminal [IPR040457] 0.8212996389891682 1.9214486289068131 0.0546751728631615 1.0 0.0977868608908959 2 Q96CW5 1 +Tim10-like [IPR004217] 0.8061371841155216 1.8524588006595024 0.063959968418191 1.0 0.1102949135385768 2 Q9Y5L4 1 +SLIDE domain [IPR015195] 0.8025270758122725 1.835986239916477 0.0663596917529809 1.0 0.1138012641818203 2 P28370 1 +ISWI, HAND domain [IPR015194] 0.8025270758122725 1.835986239916477 0.0663596917529809 1.0 0.1138012641818203 2 P28370 1 +ABC transporter-like, ATP-binding domain [IPR003439] 0.7042949086679792 1.7802510807136305 0.0750348791255306 1.0 0.1252751343406438 10 O75027,P33527,Q8NE71,O15439,Q9NRK6 5 +ABC transporter type 1, transmembrane domain [IPR011527] 0.7933670416501055 1.7434496024844044 0.0812551103036209 1.0 0.1329007900831474 6 P33527,O75027 2 +Diaphanous autoregulatory (DAD) domain [IPR014767] 0.7743682310469291 1.706944016053614 0.0878324585447996 1.0 0.1417710637922284 2 Q9NSV4 1 +Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564] 0.9506233729254324 1.69942286946123 0.0892395359717892 1.0 0.1435458834997629 3 Q13505 1 +Metaxin, glutathione S-transferase domain [IPR033468] 0.9506233729254324 1.69942286946123 0.0892395359717892 1.0 0.1435458834997629 3 Q13505 1 +Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain [IPR008152] 0.781562520487384 1.617914330994365 0.1056810613730578 1.0 0.1624377805551956 5 Q10567 1 +Ribosomal protein S5, C-terminal [IPR005324] 0.7530685920577591 1.6087708690700924 0.107666452901828 1.0 0.1645667983450339 2 P82675 1 +Ribosomal protein S5, N-terminal [IPR013810] 0.7530685920577591 1.6087708690700924 0.107666452901828 1.0 0.1645667983450339 2 P82675 1 +JAB1/MPN/MOV34 metalloenzyme domain [IPR000555] 0.7072097033197038 1.5941899850642858 0.1108934889546597 1.0 0.1679593791175703 8 O00487 1 +GMP phosphodiesterase, delta subunit [IPR008015] 0.9208085070526096 1.5903084808660164 0.1117652879074793 1.0 0.1686279636096631 3 A6NIH7 1 +Ribosome receptor lysine/proline rich [IPR007794] 0.7469314079422357 1.580411293584169 0.114012706896583 1.0 0.1712391620956401 2 Q86UP2 1 +Translation initiation factor IF- 2, domain 3 [IPR023115] 0.7382671480144377 1.5403294840734298 0.1234800603826415 1.0 0.181831205636016 2 P46199 1 +Transketolase, C-terminal domain [IPR033248] 0.7342960288808636 1.5219434771511942 0.1280232439996198 1.0 0.1872219620896696 2 P29401 1 +CARD domain [IPR001315] 0.7324909747292391 1.513583440689905 0.1301315236290681 1.0 0.1892379913708691 2 O95999 1 +Circularly permuted (CP)-type guanine nucleotide-binding (G) domain [IPR030378] 0.7530256882277554 1.5046139599714383 0.1324233551050704 1.0 0.1916156917639394 5 Q9NVN8 1 +Tim44-like domain [IPR007379] 0.7184115523465673 1.448328398195435 0.1475252291576025 1.0 0.2096978592288942 2 Q9BRJ2 1 +LEM-like domain [IPR013146] 0.7148014440433182 1.4315866860829076 0.1522621421622563 1.0 0.2151209684059964 2 P42166 1 +Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal [IPR007886] 0.7043321299638956 1.3830267334430837 0.1666566689518829 1.0 0.230846685657979 2 Q13423 1 +Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain [IPR007698] 0.7043321299638956 1.3830267334430837 0.1666566689518829 1.0 0.230846685657979 2 Q13423 1 +ARHGEF1-like, PH domain [IPR041020] 0.7032490974729209 1.3780031788030258 0.1682023066990856 1.0 0.2325735686230248 2 Q92974 1 +MPN domain [IPR037518] 0.5891710054087531 1.332296755753508 0.1827626928018726 1.0 0.2474283312721634 11 O00487 1 +Linker histone H1/H5, domain H15 [IPR005818] 0.6872740419378363 1.3104499469955415 0.1900436662928899 1.0 0.2553609194747295 6 P10412,P16403,P16402,Q92522,P07305 5 +DEAD/DEAH box helicase domain [IPR011545] 0.4082987837666793 1.3062787110670468 0.1914577940745054 1.0 0.2569652049280597 41 O00148,Q9H2U1,O94761,Q8NHQ9,Q86XP3 5 +G-protein, beta subunit [IPR001632] 0.6819494584837511 1.2792611227320991 0.2008051181443635 1.0 0.266261099459869 2 Q9NVX2 1 +GTP binding domain [IPR006073] 0.5739481046023029 1.2570521100320031 0.2087347667993651 1.0 0.2732400144193596 11 Q13823,Q9NTK5,O75616,P55039,A4D1E9,Q9BZE4,Q9NVN8 7 +60S ribosomal protein L10P, insertion domain [IPR040637] 0.6768953068592023 1.2558610334883706 0.2091663584805632 1.0 0.273651502630961 2 P05388 1 +Intermediate filament head, DNA-binding domain [IPR006821] 0.8075282262361085 1.2347117955250595 0.2169377843623996 1.0 0.2817522315592812 4 P07196 1 +C-CAP/cofactor C-like domain [IPR017901] 0.6703971119133536 1.2258031960990563 0.220272744179246 1.0 0.2849870204625056 2 Q01518 1 +CARP motif [IPR006599] 0.6703971119133536 1.2258031960990563 0.220272744179246 1.0 0.2849870204625056 2 Q01518 1 +cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain [IPR003117] 0.6653429602888048 1.202451344936469 0.2291887062758046 1.0 0.2942389661428647 2 P10644 1 +Serpin domain [IPR023796] 0.6628158844765306 1.1907854679883183 0.2337378151930698 1.0 0.299420450417467 2 P50454 1 +Rpn11/EIF3F, C-terminal [IPR024969] 0.7939576021830093 1.1849173501823924 0.2360501267266135 1.0 0.3017201510295268 4 O00487 1 +BTB/POZ domain [IPR000210] 0.7864884393063565 1.15755277531899 0.2470465905344896 1.0 0.3149135676174215 4 Q96CX2,Q9NXV2,Q9P2R3 3 +Ribonuclease II/R [IPR001900] 0.6523465703971079 1.1425399002050438 0.2532296707327797 1.0 0.3213910013541641 2 Q8IYB7 1 +Dis3-like cold-shock domain 2 [IPR041505] 0.6523465703971079 1.1425399002050438 0.2532296707327797 1.0 0.3213910013541641 2 Q8IYB7 1 +Rrp44-like cold shock domain [IPR033771] 0.6523465703971079 1.1425399002050438 0.2532296707327797 1.0 0.3213910013541641 2 Q8IYB7 1 +Calcineurin-like phosphoesterase domain, ApaH type [IPR004843] 0.6005177643918154 1.1237813157229106 0.2611058097933112 1.0 0.3310271374565933 8 Q6ZT21 1 +Serine hydroxymethyltransferase-like domain [IPR039429] 0.6451263537906096 1.1093610108724934 0.2672744749855842 1.0 0.3362903636745841 2 P34897 1 +Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219] 0.7851209823040808 1.0913112282765645 0.2751359587292012 1.0 0.3452512514376106 3 O75116,Q9H0H5 2 +PPM-type phosphatase domain [IPR001932] 0.7616222904676202 1.066767624578038 0.286076781567953 1.0 0.3578259422184364 4 Q9H0C8,P49593 2 +DnaJ domain [IPR001623] 0.4628330555051368 0.9919204461104948 0.3212363343608082 1.0 0.3960726911770346 15 Q13217,Q96EY1 2 +OBG-type guanine nucleotide-binding (G) domain [IPR031167] 0.6245030719190257 0.9910801009933142 0.3216464687612252 1.0 0.396368985263305 5 P55039,Q9NTK5,A4D1E9,Q9BZE4 4 +ERM family, FERM domain C-lobe [IPR041789] 0.7415268134999096 0.9335502387907456 0.3505359440593913 1.0 0.4301529408173604 3 P26038 1 +Macro domain [IPR002589] 0.7408966767429077 0.931294107974076 0.3517014489586096 1.0 0.4313563751284262 3 Q9P0M6 1 +Protein kinase domain [IPR000719] 0.3615475319270103 0.8986386610891125 0.3688451588681687 1.0 0.4504890637353771 45 Q9UHY1,O95747,Q14004,O43318,Q7KZI7,P31749,P31751,Q99640,P36507,Q13043 10 +Complex 1 LYR protein domain [IPR008011] 0.5945848375451217 0.8805727893784312 0.3785490917482301 1.0 0.4596948908118466 2 P56556 1 +Formin, FH3 domain [IPR010472] 0.7261642110161095 0.8787981081182367 0.3795107522574579 1.0 0.4603836256595149 3 Q9NSV4 1 +Formin, GTPase-binding domain [IPR010473] 0.7261642110161095 0.8787981081182367 0.3795107522574579 1.0 0.4603836256595149 3 Q9NSV4 1 +GINS subunit, domain A [IPR021151] 0.7255326832791564 0.8765592928913409 0.3807260577241447 1.0 0.4610209577893638 3 Q9BRX5,Q9Y248 2 +CYRIA/CYRIB, Rac1 binding domain [IPR009828] 0.5913357400721974 0.8661541256710049 0.3864056465188299 1.0 0.4672905590543777 2 Q7L576 1 +Histone H2A, C-terminal domain [IPR032454] 0.7175729702321781 0.8484300111244578 0.3961985349191448 1.0 0.4781423890906329 3 Q9P0M6 1 +Histone H2A/H2B/H3 [IPR007125] 0.7175729702321781 0.8484300111244578 0.3961985349191448 1.0 0.4781423890906329 3 Q9P0M6 1 +Immunoglobulin V-set domain [IPR013106] 0.7068212348573096 0.8107134698290525 0.4175302361679751 1.0 0.500264666948693 3 P78310 1 +Dbl homology (DH) domain [IPR000219] 0.7035030697002491 0.7991436484489934 0.4242071227194337 1.0 0.5077432945780299 3 Q92974,Q14155 2 +K Homology domain, type 1 [IPR004088] 0.3966227176324081 0.7977276433908618 0.4250285584688409 1.0 0.508465738322027 24 Q96PU8,Q8IWZ3,Q15366,Q9Y6M1,Q9Y2W6,P51116 6 +Peptidase M28 [IPR007484] 0.7027807872878183 0.7966297960127466 0.425666067399614 1.0 0.5089675211632679 3 P02786,Q7Z2K6 2 +Kinesin motor domain [IPR001752] 0.4898154818122675 0.7715143972685866 0.4404020920129725 1.0 0.5244380014072846 10 O00139,Q02241,Q99661,Q12756 4 +Proteasomal ATPase OB C-terminal domain [IPR032501] 0.5648925903077657 0.7589785421079761 0.4478653929811118 1.0 0.5322392195610565 5 P62191,P62333 2 +Metastasis-associated protein MTA1, R1 domain [IPR035170] 0.5581227436823052 0.7217363836578994 0.4704565683110948 1.0 0.5556911085213033 2 Q13330 1 +ELM2 domain [IPR000949] 0.5581227436823052 0.7217363836578994 0.4704565683110948 1.0 0.5556911085213033 2 Q13330 1 +Pleckstrin homology domain [IPR001849] 0.3858884501310474 0.7191111876555619 0.4720724146278865 1.0 0.5573176609719207 23 P20936,P31749,Q12756,Q9NQW6,P31751,Q9Y5P4 6 +S100/CaBP-9k-type, calcium binding, subdomain [IPR013787] 0.5509025270758068 0.691195991431694 0.4894423826426699 1.0 0.5757855449032215 2 P31949 1 +Coatomer, WD associated region [IPR006692] 0.5501805054151572 0.6881614811090855 0.4913510974399786 1.0 0.5765779092131272 2 P35606 1 +Vps4 oligomerisation, C-terminal [IPR015415] 0.5498194945848321 0.686645597464062 0.4923060871789522 1.0 0.5774082449626505 2 Q9UN37 1 +Myosin tail [IPR002928] 0.5480144404332075 0.6790800354432587 0.497087151572597 1.0 0.582722959201628 2 P35579 1 +Helicase superfamily 1/2, ATP-binding domain [IPR014001] 0.3305384807897119 0.6696887625462784 0.503056216746324 1.0 0.5885379498175038 55 Q9BQ39,O00148,Q9H2U1,O94761,Q8NHQ9,Q86XP3,Q14527,Q2NKX8,P46100 9 +K Homology domain [IPR004087] 0.3730769088316508 0.647427779572184 0.5173551217310652 1.0 0.6034517012095484 24 Q96PU8,Q8IWZ3,Q15366,Q9Y6M1,Q9Y2W6 5 +Peptidase M3A/M3B catalytic domain [IPR001567] 0.6570982767949234 0.6415865782722872 0.5211416498745343 1.0 0.607261413283656 3 Q99797 1 +TGS [IPR004095] 0.5125928667610686 0.610038960878204 0.541835999043075 1.0 0.6291767272470334 6 P55039,Q9BW92 2 +RNA helicase, DEAD-box type, Q motif [IPR014014] 0.3686720036290074 0.6065718507399136 0.5441350859158356 1.0 0.6315322180644258 22 O00148,Q8NHQ9 2 +Helicase, C-terminal [IPR001650] 0.322523132585005 0.6045184640062328 0.5454989972628961 1.0 0.632486169702732 56 Q9BQ39,O00148,Q9H2U1,O94761,Q8NHQ9,Q86XP3,Q14527,Q2NKX8,P46100 9 +AAA ATPase, AAA+ lid domain [IPR041569] 0.39206691265436 0.5929030166348521 0.5532460590538022 1.0 0.6402293042477218 14 Q8NBU5,Q96TA2 2 +Peptidase C14A, caspase catalytic domain [IPR015917] 0.6417600462103835 0.5916315512063265 0.5540973412940866 1.0 0.6402293042477218 3 P42574 1 +Peptidase C14, caspase non-catalytic subunit p10 [IPR002138] 0.6417600462103835 0.5916315512063265 0.5540973412940866 1.0 0.6402293042477218 3 P42574 1 +Peptidase C14, p20 domain [IPR001309] 0.6417600462103835 0.5916315512063265 0.5540973412940866 1.0 0.6402293042477218 3 P42574 1 +RNA polymerase Rpb1, domain 1 [IPR007080] 0.6348565752054931 0.569561893595119 0.5689748802551906 1.0 0.6532156274056148 3 O95602 1 +RNA polymerase Rpb1, domain 4 [IPR007083] 0.6348565752054931 0.569561893595119 0.5689748802551906 1.0 0.6532156274056148 3 O95602 1 +RNA polymerase Rpb1, domain 3 [IPR007066] 0.6348565752054931 0.569561893595119 0.5689748802551906 1.0 0.6532156274056148 3 O95602 1 +RNA polymerase, alpha subunit [IPR000722] 0.6348565752054931 0.569561893595119 0.5689748802551906 1.0 0.6532156274056148 3 O95602 1 +RNA polymerase, N-terminal [IPR006592] 0.6348565752054931 0.569561893595119 0.5689748802551906 1.0 0.6532156274056148 3 O95602 1 +RNA polymerase Rpb1, domain 5 [IPR007081] 0.6348565752054931 0.569561893595119 0.5689748802551906 1.0 0.6532156274056148 3 O95602 1 +Amine oxidase [IPR002937] 0.6334416756951973 0.5650723395669551 0.5720245615561799 1.0 0.6547843681570005 3 O60341,Q8NB78 2 +Matrin/U1-C-like, C2H2-type zinc finger [IPR003604] 0.4740316905214509 0.525220477413621 0.5994299312904976 1.0 0.6831393845859479 7 Q5VUA4,Q969S3 2 +UAS [IPR006577] 0.5093862815884416 0.5235489220649486 0.6005923157289934 1.0 0.683936220364224 2 Q96CS3 1 +Importin-beta, N-terminal domain [IPR001494] 0.3781855227908296 0.5233723105422659 0.6007151892659208 1.0 0.683936220364224 14 Q9UI26,O43592 2 +Intermediate filament, rod domain [IPR039008] 0.4573107518890721 0.520263008743467 0.6028802744750676 1.0 0.685398227289239 8 P07196 1 +Transketolase-like, pyrimidine-binding domain [IPR005475] 0.6182737450342984 0.5177076123260307 0.6046622862513589 1.0 0.6870894723031508 3 P29401,P11177 2 +FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179] 0.4172044546966511 0.5120467944881842 0.608618259988174 1.0 0.6912481843369334 11 Q9Y680,O95302 2 +Rho GTPase-activating protein domain [IPR000198] 0.4945877376980997 0.5037925567278361 0.614407158761056 1.0 0.6971445350259138 5 Q01968 1 +Electron transfer flavoprotein, alpha/beta-subunit, N-terminal [IPR014730] 0.5007220216606437 0.4906129273724147 0.6237002414131649 1.0 0.7070016335397411 2 P38117 1 +Ubiquitin-activating enzyme E1, FCCH domain [IPR032418] 0.4989169675090191 0.4838545128901917 0.6284891242953294 1.0 0.7110487717427527 2 P22314 1 +Ubiquitin-activating enzyme, SCCH domain [IPR019572] 0.4989169675090191 0.4838545128901917 0.6284891242953294 1.0 0.7110487717427527 2 P22314 1 +Ubiquitin-activating enzyme E1, C-terminal [IPR018965] 0.4989169675090191 0.4838545128901917 0.6284891242953294 1.0 0.7110487717427527 2 P22314 1 +Ubiquitin-activating enzyme E1, four-helix bundle [IPR032420] 0.4989169675090191 0.4838545128901917 0.6284891242953294 1.0 0.7110487717427527 2 P22314 1 +Heat shock protein Hsp90, N-terminal [IPR020575] 0.5868803853317258 0.4722954870277888 0.6367158911733246 1.0 0.7196585423721742 4 Q12931,P08238 2 +CBS domain [IPR000644] 0.4751624437313194 0.4391321040584267 0.660565818068334 1.0 0.7401635234620699 5 Q8NE01 1 +Clathrin/coatomer adaptor, adaptin-like, N-terminal [IPR002553] 0.4062676045356006 0.4167675395270411 0.6768484475625638 1.0 0.7573174863907114 10 Q10567 1 +Immunoglobulin subtype 2 [IPR003598] 0.4419748738443651 0.4114122660549626 0.6807702611812867 1.0 0.7602477462187192 7 Q9Y639 1 +Immunoglobulin subtype [IPR003599] 0.4419748738443651 0.4114122660549626 0.6807702611812867 1.0 0.7602477462187192 7 Q9Y639 1 +Band 7 domain [IPR001107] 0.4550052142052142 0.4079660712333643 0.6832985843408004 1.0 0.7623417284184646 6 Q99623,Q9UJZ1 2 +Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091] 0.4151169843275943 0.4063750657572537 0.6844670375313111 1.0 0.7632804900134162 9 O15254 1 +GHMP kinase, C-terminal domain [IPR013750] 0.4693140794223762 0.378648865792321 0.7049486297706093 1.0 0.7803209079362264 2 Q03426 1 +CDC48, domain 2 [IPR004201] 0.4682310469314025 0.3750171436692793 0.7076477167740385 1.0 0.7812912823796622 2 P55072 1 +CDC48, N-terminal subdomain [IPR003338] 0.4682310469314025 0.3750171436692793 0.7076477167740385 1.0 0.7812912823796622 2 P55072 1 +Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245] 0.4521889285739091 0.3670952555433093 0.7135479661554498 1.0 0.7870609418746786 5 Q9UHY1 1 +TRASH domain [IPR011017] 0.4642599277978272 0.3618421382733822 0.7174700009558956 1.0 0.7887776647343667 2 P83731 1 +ATPase, AAA-type, core [IPR003959] 0.3216947014674663 0.3598896607535936 0.7189296492315287 1.0 0.7900102642685443 26 Q9NVI7,Q9Y276,Q8NBU5,Q96TA2 4 +SNF2, N-terminal [IPR000330] 0.3651032325444613 0.3493232443786945 0.7268466497937562 1.0 0.7977342059988164 12 Q14527,Q86WJ1,Q2NKX8,P46100,P28370 5 +LSM domain, eukaryotic/archaea-type [IPR001163] 0.4299130410749622 0.3295923191618337 0.7417080270253371 1.0 0.8104618609911689 6 P62314 1 +Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase [IPR006186] 0.4370195977813554 0.3225381620712972 0.7470450319768485 1.0 0.8151487165189174 5 Q08209 1 +Disulphide isomerase [IPR005788] 0.4141669678351927 0.2605088747854369 0.794471270496045 1.0 0.858470345063782 5 P13667,P07237,P30101,Q8NBS9 4 +TIP49, P-loop domain [IPR010339] 0.4296028880866373 0.2569972183136745 0.7971809204379441 1.0 0.8602746273331929 2 Q9Y265 1 +RuvB-like, AAA-lid domain [IPR041048] 0.4296028880866373 0.2569972183136745 0.7971809204379441 1.0 0.8602746273331929 2 Q9Y265 1 +Nucleoside phosphorylase domain [IPR000845] 0.4281588447653369 0.2530490461269676 0.8002303128919976 1.0 0.863094986270759 2 P00491 1 +2Fe-2S ferredoxin-type iron-sulfur binding domain [IPR001041] 0.4238267148014367 0.2414171643883381 0.8092318108575236 1.0 0.8715953145092109 2 P28331 1 +Nucleotidyl transferase domain [IPR005835] 0.5077645359335556 0.2280757568336885 0.8195873466723311 1.0 0.880716789656179 3 Q96IJ6,Q9Y5P6 2 +Ribosomal protein L7, eukaryotic/archaeal [IPR035808] 0.4162454873646136 0.221839297069003 0.8244389869061615 1.0 0.8843017442274729 2 P18124 1 +Ribosomal protein L30, N-terminal [IPR012988] 0.4162454873646136 0.221839297069003 0.8244389869061615 1.0 0.8843017442274729 2 P18124 1 +Ribosomal protein L30, ferredoxin-like fold domain [IPR016082] 0.4162454873646136 0.221839297069003 0.8244389869061615 1.0 0.8843017442274729 2 P18124 1 +Immunoglobulin-like domain [IPR007110] 0.3331158404412411 0.202842290869171 0.8392583016535995 1.0 0.8989577219180822 11 Q9Y639 1 +Zinc finger, FYVE-related [IPR017455] 0.4712451337892456 0.1859369686777431 0.8524941908719534 1.0 0.9101450168789976 4 Q9P2R3,Q96T51 2 +FYVE zinc finger [IPR000306] 0.4712451337892456 0.1859369686777431 0.8524941908719534 1.0 0.9101450168789976 4 Q9P2R3,Q96T51 2 +Septin-type guanine nucleotide-binding (G) domain [IPR030379] 0.3787793426569537 0.1779813235389526 0.858737643212528 1.0 0.9156206757688626 5 Q9UHD8,Q14141 2 +PIK-related kinase, FAT [IPR003151] 0.3935018050541447 0.169206119582552 0.8656345164674062 1.0 0.9204514630683036 2 P42345 1 +PIK-related kinase [IPR014009] 0.3935018050541447 0.169206119582552 0.8656345164674062 1.0 0.9204514630683036 2 P42345 1 +FATC domain [IPR003152] 0.3935018050541447 0.169206119582552 0.8656345164674062 1.0 0.9204514630683036 2 P42345 1 +Domain of unknown function DUF1605 [IPR011709] 0.3283249919803479 0.1654026018427692 0.8686271059084398 1.0 0.9223729140993168 10 Q9H2U1,Q9H6S0,Q7L2E3,Q7Z478 4 +Helicase-associated domain [IPR007502] 0.3283249919803479 0.1654026018427692 0.8686271059084398 1.0 0.9223729140993168 10 Q9H2U1,Q9H6S0,Q7L2E3,Q7Z478 4 +Phox homology [IPR001683] 0.3417984009240637 0.1597214038641189 0.8731005395127913 1.0 0.9267005582795548 8 Q13596 1 +GHMP kinase N-terminal domain [IPR006204] 0.4694835680751152 0.1567333830756483 0.8754549763294543 1.0 0.9283561629954324 3 Q03426,P53602 2 +SMARCC, SWIRM-associated domain [IPR032448] 0.3844765342960232 0.1509014258282845 0.8800534757196665 1.0 0.9315395974284362 2 Q8TAQ2 1 +SMARCC, C-terminal [IPR032451] 0.3844765342960232 0.1509014258282845 0.8800534757196665 1.0 0.9315395974284362 2 Q8TAQ2 1 +SMARCC, N-terminal [IPR032450] 0.3844765342960232 0.1509014258282845 0.8800534757196665 1.0 0.9315395974284362 2 Q8TAQ2 1 +EF-hand domain [IPR002048] 0.2598633232266062 0.1475408906910869 0.8827051067626028 1.0 0.9327312062372994 38 O95202,Q9H4M9,P80303,O95302,P35609 5 +Tubulin/FtsZ, GTPase domain [IPR003008] 0.3559066808906926 0.145837185258275 0.884049920122407 1.0 0.9327312062372994 6 P68371,P04350,Q13885 3 +Tubulin/FtsZ, 2-layer sandwich domain [IPR018316] 0.3559066808906926 0.145837185258275 0.884049920122407 1.0 0.9327312062372994 6 P68371,P04350,Q13885 3 +Serine-tRNA ligase catalytic core domain [IPR033729] 0.3815884476534232 0.1453551383833572 0.8844304827957647 1.0 0.9327312062372994 2 P49591 1 +WHEP-TRS domain [IPR000738] 0.4476156069364276 0.1449176709747124 0.8847758742970784 1.0 0.9327312062372994 4 P41250,P23381,P56192 3 +Formin, FH2 domain [IPR015425] 0.4420504115439202 0.1362107167654714 0.8916547033759532 1.0 0.9372896857311614 4 Q9NSV4 1 +Rho GTPase-binding/formin homology 3 (GBD/FH3) domain [IPR014768] 0.4420504115439202 0.1362107167654714 0.8916547033759532 1.0 0.9372896857311614 4 Q9NSV4 1 +RecF/RecN/SMC, N-terminal [IPR003395] 0.3464888800622324 0.1282645905654665 0.8979395862334303 1.0 0.9423520657683572 6 O95347,Q9NTJ3,Q8IY18 3 +Reticulon [IPR003388] 0.4361362725230915 0.1273565404024553 0.8986582118097493 1.0 0.9423575862743682 4 O95197 1 +Bromo adjacent homology (BAH) domain [IPR001025] 0.4360549132948095 0.1272375946881081 0.8987523509197701 1.0 0.9423575862743682 4 O94776,Q13330,P26358 3 +Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) [IPR002314] 0.3452639190166223 0.1260804545525003 0.8996682390034854 1.0 0.9428943286188302 6 Q9BW92,P49591,Q9NP81,P41250,P07814 5 +SANT domain [IPR017884] 0.3333047799772846 0.1218578210191884 0.9030116205560328 1.0 0.9433038344070211 7 P28370,Q8TAQ2,O60264 3 +RBM3/CIRBP, RNA recognition motif [IPR034278] 0.368231046931402 0.1216539988618411 0.9031730461359128 1.0 0.9433038344070211 2 Q14011 1 +Sterile alpha motif domain [IPR001660] 0.4289210316079428 0.1171085409601204 0.9067740416032668 1.0 0.9460932557452056 4 Q9Y3Z3,Q9UQR0 2 +Ubiquitin-conjugating enzyme E2 [IPR000608] 0.3197100929051 0.114634834458469 0.9087345678013352 1.0 0.9477151390743148 8 Q16763 1 +HD/PDEase domain [IPR003607] 0.3602888086642539 0.1090625809067171 0.9131528539096376 1.0 0.949455900409392 2 Q9Y3Z3 1 +HD domain [IPR006674] 0.3602888086642539 0.1090625809067171 0.9131528539096376 1.0 0.949455900409392 2 Q9Y3Z3 1 +Sec63 domain [IPR004179] 0.4364106066454005 0.1087369548299611 0.913411129910138 1.0 0.949455900409392 3 Q9UGP8 1 +SWIRM domain [IPR007526] 0.4217826749323751 0.1075646304031796 0.9143410550054978 1.0 0.9497427780964984 4 Q8TAQ2,O60341 2 +BAT2, N-terminal [IPR009738] 0.3588447653429541 0.1068914561663696 0.9148750913480724 1.0 0.9498747612128116 2 P48634 1 +Ribosomal L28e/Mak16 [IPR029004] 0.3584837545126292 0.1063543055681439 0.9153012462564768 1.0 0.9498946681914704 2 P46779 1 +Major sperm protein (MSP) domain [IPR000535] 0.431202600216686 0.1023193048001355 0.9185032327100662 1.0 0.9520524497137332 3 Q8NHP6,O95292 2 +B3/B4 tRNA-binding domain [IPR005146] 0.3530685920577556 0.0985651700117353 0.9214835256191208 1.0 0.95376609702662 2 Q8N1G4 1 +Threonine-tRNA ligase catalytic core domain [IPR033728] 0.3447653429602824 0.0875812337741125 0.9302095181342068 1.0 0.9610929682714648 2 Q9BW92 1 +Lactate/malate dehydrogenase, C-terminal [IPR022383] 0.4039017341040576 0.08620682132637 0.9313020082627534 1.0 0.961370582611794 4 P07195,P40925,P40926 3 +Lactate/malate dehydrogenase, N-terminal [IPR001236] 0.4039017341040576 0.08620682132637 0.9313020082627534 1.0 0.961370582611794 4 P07195,P40925,P40926 3 +SANT/Myb domain [IPR001005] 0.2932747332117765 0.0795944986439878 0.9365597707820206 1.0 0.96326173422632 9 P28370,Q8TAQ2,O60264,Q8IXM2 4 +Histidine kinase/HSP90-like ATPase [IPR003594] 0.3048236177166306 0.0767071304440803 0.9388565319827976 1.0 0.9636284721406552 7 Q12931,Q15120,P08238 3 +Domain of unknown function DUF4749 [IPR031847] 0.3328519855595603 0.073773766568374 0.941190401374373 1.0 0.965599295300126 2 O00151 1 +SAP domain [IPR003034] 0.25471251031152 0.0560426844044192 0.9553078033360662 1.0 0.976413883334539 13 Q00839,P35659,P82979,Q9NWH9 4 +NOPS [IPR012975] 0.362224629830263 0.0437363230081479 0.965114585333557 1.0 0.981087736136116 3 P23246,Q15233 2 +Anticodon-binding [IPR004154] 0.3450144508670562 0.0392844916072827 0.9686635709766168 1.0 0.9827437552114252 4 Q9BW92,P07814,P41250 3 +Cation-transporting P-type ATPase, N-terminal [IPR004014] 0.3446531791907554 0.0390935838891376 0.9688157763752908 1.0 0.9827437552114252 4 P98194,P05023,P20020 3 +Cation-transporting P-type ATPase, C-terminal [IPR006068] 0.3446531791907554 0.0390935838891376 0.9688157763752908 1.0 0.9827437552114252 4 P98194,P05023,P20020 3 +Brix domain [IPR007109] 0.3528349584687604 0.039052012009489 0.9688489206261736 1.0 0.9827437552114252 3 Q9H7B2,Q8TDN6 2 +Serine-threonine protein phosphatase, N-terminal [IPR031675] 0.2642599277978265 0.0305562729629888 0.9756234149714548 1.0 0.9874696663241004 2 P62136 1 +Cullin homology domain [IPR016158] 0.2580411998554394 0.028944899682249 0.9769085358404488 1.0 0.987913571339518 5 Q13616,Q93034,Q13617,Q13618 4 +Cullin protein, neddylation domain [IPR019559] 0.2580411998554394 0.028944899682249 0.9769085358404488 1.0 0.987913571339518 5 Q13616,Q93034,Q13617,Q13618 4 +Cullin, N-terminal [IPR001373] 0.2581344902386031 0.0271651566212745 0.9783280064320709 1.0 0.9889205573895424 6 Q13618,Q13616,Q93034,Q86Y37,Q13617 5 +Glutamine amidotransferase type 2 domain [IPR017932] 0.2723004694835619 0.0193299342053909 0.9845779043438052 1.0 0.9935170033456296 3 Q06203,Q06210 2 +Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant [IPR000866] 0.2337427745664787 0.0140379478237313 0.9887997060297128 1.0 0.9962745728205552 4 P30041,P30048,P32119 3 +Peroxiredoxin, C-terminal [IPR019479] 0.2337427745664787 0.0140379478237313 0.9887997060297128 1.0 0.9962745728205552 4 P30041,P30048,P32119 3 diff --git a/interpro_domain/selections.json b/interpro_domain/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..f9b46d55a3d9f1d79742154a3e4bacd24cc6f0b4 --- /dev/null +++ b/interpro_domain/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1-acyl-sn-glycerol-3-phosphate acyltransferase [IPR004552]", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, SH3 domain [IPR035724]", "116kDa U5 small nuclear ribonucleoprotein component, C-terminal [IPR035655]", "116kDa U5 small nuclear ribonucleoprotein component, N-terminal [IPR031950]", "14-3-3 domain [IPR023410]", "2-oxoacid dehydrogenase acyltransferase, catalytic domain [IPR001078]", "2-oxoglutarate dehydrogenase E1 component, N-terminal domain [IPR032106]", "26S proteasome non-ATPase regulatory subunit RPN1, C-terminal [IPR041433]", "26S proteasome regulatory subunit RPN2, C-terminal [IPR040623]", "26S proteasome regulatory subunit RPN5, C-terminal domain [IPR040896]", "26S proteasome regulatory subunit Rpn6, N-terminal [IPR040773]", "26S proteasome regulatory subunit Rpn7, N-terminal [IPR045135]", "26S proteasome regulatory subunit, C-terminal [IPR013586]", "2Fe-2S ferredoxin-type iron-sulfur binding domain [IPR001041]", "3'-5' exonuclease domain [IPR002562]", "3-beta hydroxysteroid dehydrogenase/isomerase [IPR002225]", "3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108]", "3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176]", "3-hydroxyisobutyrate dehydrogenase, NAD-binding domain [IPR029154]", "3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal [IPR001104]", "4'-phosphopantetheinyl transferase domain [IPR008278]", "40S ribosomal protein S11, N-terminal [IPR032440]", "40S ribosomal protein S4, C-terminal domain [IPR032277]", "40S ribosomal protein SA, C-terminal domain [IPR032281]", "4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896]", "5'-AMP-activated protein kinase alpha 1 catalytic subunit, C-terminal [IPR039137]", "6-phosphogluconate dehydrogenase, C-terminal [IPR006114]", "6-phosphogluconate dehydrogenase, NADP-binding [IPR006115]", "6-phosphogluconolactonase, DevB-type [IPR005900]", "60S ribosomal protein L10P, insertion domain [IPR040637]", "60S ribosomal protein L4, C-terminal domain [IPR025755]", "6S proteasome subunit Rpn6, C-terminal helix domain [IPR040780]", "A kinase-anchoring protein AKAP5 and AKAP12, calmodulin (CaM)-binding motif [IPR001573]", "AAA ATPase, AAA+ lid domain [IPR041569]", "AAA+ ATPase domain [IPR003593]", "AAR2, C-terminal [IPR033648]", "AAR2, N-terminal [IPR033647]", "AARP2CN [IPR012948]", "AATF leucine zipper-containing domain [IPR025160]", "ABC transporter type 1, transmembrane domain [IPR011527]", "ABC transporter-like, ATP-binding domain [IPR003439]", "ABC-transporter extension domain [IPR032781]", "ADAR1, first double-stranded RNA binding domain [IPR044456]", "ADAR1, third double-stranded RNA binding domain [IPR044457]", "ADD domain [IPR025766]", "ADNP, zinc finger domain [IPR045762]", "AGC-kinase, C-terminal [IPR000961]", "AIMP2, lysyl-tRNA synthetase binding domain [IPR031889]", "AIMP2, thioredoxin-like domain [IPR041503]", "ALIX V-shaped domain [IPR025304]", "AMP-binding enzyme, C-terminal domain [IPR025110]", "AMP-dependent synthetase/ligase [IPR000873]", "AMPK, C-terminal adenylate sensor domain [IPR032270]", "AP complex, mu/sigma subunit [IPR022775]", "AP-2 complex subunit mu, N-terminal [IPR043532]", "AP-3 complex subunit beta 1, serine-rich domain [IPR029394]", "AP-3 complex subunit beta, C-terminal domain [IPR029390]", "AP-3 complex subunit delta domain, metazoa [IPR010474]", "AP180 N-terminal homology (ANTH) domain [IPR011417]", "APC10/DOC domain [IPR004939]", "ARHGEF1-like, PH domain [IPR041020]", "ARHGEF2, PH domain [IPR037806]", "ARID DNA-binding domain [IPR001606]", "ARMET, C-terminal [IPR019345]", "ARMET, N-terminal [IPR045332]", "ATP synthase, F1 complex, alpha subunit nucleotide-binding domain [IPR033732]", "ATP synthase, alpha subunit, C-terminal [IPR000793]", "ATP-citrate lyase/succinyl-CoA ligase [IPR005811]", "ATP-citrate synthase, citrate-binding domain [IPR032263]", "ATP-cone domain [IPR005144]", "ATP-dependent DNA helicase RecQ, zinc-binding domain [IPR032284]", "ATP-dependent RNA helicase Ski2, C-terminal [IPR012961]", "ATP-dependent RNA helicase eIF4A, DEAD-box helicase domain [IPR044728]", "ATP-dependent helicase, C-terminal [IPR006555]", "ATP-grasp fold [IPR011761]", "ATP-grasp fold, succinyl-CoA synthetase-type [IPR013650]", "ATP-sulfurylase PUA-like domain [IPR025980]", "ATP:guanido phosphotransferase, N-terminal [IPR022413]", "ATP:guanido phosphotransferase, catalytic domain [IPR022414]", "ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]", "ATPase, AAA-type, core [IPR003959]", "ATPase, BadF/BadG/BcrA/BcrD type [IPR002731]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain [IPR004100]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain [IPR000194]", "ATPase, V1 complex, subunit H, C-terminal [IPR011987]", "ATPase, dynein-related, AAA domain [IPR011704]", "ATPsynthase alpha/beta subunit, N-terminal extension [IPR031686]", "ATRX, ADD domain [IPR041430]", "AWS domain [IPR006560]", "Abnormal spindle-like microcephaly-associated protein, ASH domain [IPR031549]", "Acetyl-CoA carboxylase [IPR034733]", "Acetyl-CoA carboxylase, central domain [IPR013537]", "Acetyl-coA carboxylase zinc finger domain [IPR041010]", "Acetyl-coenzyme A carboxyltransferase, C-terminal [IPR011763]", "Acetyl-coenzyme A carboxyltransferase, N-terminal [IPR011762]", "Acid ceramidase, N-terminal [IPR029130]", "Acinus, RNA recognition motif [IPR034257]", "Aconitase A/isopropylmalate dehydratase small subunit, swivel domain [IPR000573]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain [IPR001030]", "Actin-depolymerising factor homology domain [IPR002108]", "Activating signal cointegrator 1 complex subunit 2, CUE domain [IPR041800]", "Activator of Hsp90 ATPase, N-terminal [IPR015310]", "Acyl transferase [IPR014043]", "Acyl-CoA dehydrogenase family member 10/11, N-terminal [IPR041726]", "Acyl-CoA dehydrogenase/oxidase C-terminal [IPR009075]", "Acyl-CoA dehydrogenase/oxidase, N-terminal [IPR013786]", "Acyl-CoA oxidase, C-terminal [IPR002655]", "Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091]", "Acyl-CoA-binding protein, ACBP [IPR000582]", "Acyl-coenzyme A oxidase, N-terminal [IPR029320]", "Acylamino-acid-releasing enzyme, N-terminal domain [IPR045550]", "Acylglycerol kinase, C-terminal [IPR045579]", "Acyltransferase, C-terminal domain [IPR032098]", "Adenosine deaminase domain [IPR001365]", "Adenosine deaminase/editase [IPR002466]", "Adenylate cyclase-associated CAP, C-terminal [IPR013912]", "Adenylate cyclase-associated CAP, N-terminal [IPR013992]", "Adenylate kinase, active site lid domain [IPR007862]", "Adenylosuccinate lyase C-terminal [IPR019468]", "Afadin, cargo binding domain [IPR037977]", "Agenet-like domain [IPR008395]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal [IPR007886]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain [IPR007698]", "Alanyl-tRNA synthetase, class IIc, N-terminal [IPR018164]", "Alanyl-tRNA synthetase, class IIc, core domain [IPR018165]", "Alcohol dehydrogenase, N-terminal [IPR013154]", "Alcohol dehydrogenase-like, C-terminal [IPR013149]", "Aldehyde dehydrogenase domain [IPR015590]", "Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant [IPR000866]", "Alpha Spectrin, SH3 domain [IPR035825]", "Alpha crystallin/Hsp20 domain [IPR002068]", "Alpha galactosidase A, C-terminal beta-sandwich domain [IPR035373]", "Alpha-2-macroglobulin RAP, C-terminal [IPR010483]", "Alpha-2-macroglobulin RAP, domain 2 [IPR038001]", "Alpha-2-macroglobulin RAP, domain 3 [IPR037999]", "Alpha-2-macroglobulin receptor-associated protein, domain 1 [IPR009066]", "Alpha-D-phosphohexomutase, C-terminal [IPR005843]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain I [IPR005844]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain II [IPR005845]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain III [IPR005846]", "Alpha-L-fucosidase, C-terminal [IPR031919]", "Alpha-N-acetylglucosaminidase, C-terminal [IPR024732]", "Alpha-N-acetylglucosaminidase, N-terminal [IPR024240]", "Alpha-N-acetylglucosaminidase, tim-barrel domain [IPR024733]", "Alpha-glycerophosphate oxidase, C-terminal [IPR031656]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like [IPR027450]", "Alpha-ketoglutarate-dependent dioxygenase FTO, C-terminal [IPR024366]", "Alpha-ketoglutarate-dependent dioxygenase FTO, catalytic domain [IPR024367]", "Alpha/beta hydrolase fold-1 [IPR000073]", "Amidase signature domain [IPR023631]", "Amidohydrolase-related [IPR006680]", "Amidophosphoribosyltransferase, N-terminal [IPR035584]", "Amine oxidase [IPR002937]", "Amino acid permease, N-terminal [IPR013612]", "Amino acid permease/ SLC12A domain [IPR004841]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding [IPR045462]", "Aminoacyl-tRNA synthetase, class II (D/K/N) [IPR004364]", "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) [IPR002314]", "Aminoacyl-tRNA synthetase, class II [IPR006195]", "Aminoacyl-tRNA synthetase, class Ia [IPR002300]", "Aminoglycoside phosphotransferase [IPR002575]", "Aminopeptidase N-like , N-terminal domain [IPR045357]", "Aminopeptidase P [IPR033740]", "Aminopeptidase P, N-terminal [IPR007865]", "Aminotransferase class V domain [IPR000192]", "Aminotransferase, class I/classII [IPR004839]", "Anaphase-promoting complex subunit 4, WD40 domain [IPR024977]", "Anaphase-promoting complex subunit 5 domain [IPR026000]", "Ancestral coatomer element 1, Sec16/Sec31 [IPR024298]", "Angiomotin, C-terminal [IPR024646]", "Anillin homology domain [IPR012966]", "Anillin, N-terminal domain [IPR031970]", "Anillin, PH domain [IPR037840]", "Anion-transporting ATPase-like domain [IPR025723]", "Ankyrin repeat and LEM domain-containing protein 2, LEM domain [IPR035006]", "Ankyrin, UPA domain [IPR040745]", "Ankyrin-3, death domain [IPR037971]", "Anticodon-binding [IPR004154]", "Anticodon-binding domain [IPR019181]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal [IPR006190]", "ApaG domain [IPR007474]", "Apoptosis-antagonizing transcription factor, C-terminal [IPR012617]", "Archaeal primase DnaG/twinkle, TOPRIM domain [IPR034154]", "Arf GTPase activating protein [IPR001164]", "Arfaptin homology (AH) domain [IPR010504]", "Arginyl tRNA synthetase N-terminal domain [IPR005148]", "Arginyl-tRNA synthetase, catalytic core domain [IPR035684]", "Ariadne domain [IPR045840]", "Armadillo repeat-containing domain [IPR006911]", "Aromatic amino acid beta-eliminating lyase/threonine aldolase [IPR001597]", "Asparagine synthase [IPR001962]", "Asparagine synthase, N-terminal domain [IPR033738]", "Aspartate/glutamate/uridylate kinase [IPR001048]", "Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain [IPR006131]", "Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding [IPR006132]", "Aspartic peptidase, DDI1-type [IPR019103]", "Aspartyl beta-hydroxylase/Triadin domain [IPR007943]", "Aspartyl/asparaginy/proline hydroxylase [IPR007803]", "Ataxin 2, SM domain [IPR025852]", "Ataxin-10 domain [IPR019156]", "Ataxin-2, C-terminal [IPR009818]", "Aurora-A binding [IPR015128]", "Autophagy-related, C-terminal [IPR015412]", "B-block binding subunit of TFIIIC [IPR007309]", "B-box, C-terminal [IPR003649]", "B-box-type zinc finger [IPR000315]", "B3/B4 tRNA-binding domain [IPR005146]", "B30.2/SPRY domain [IPR001870]", "BAG domain [IPR003103]", "BAP29/BAP31, transmembrane domain [IPR040463]", "BAR domain [IPR004148]", "BAT2, N-terminal [IPR009738]", "BCL10, CARD domain [IPR042143]", "BCS1, N-terminal [IPR014851]", "BEACH domain [IPR000409]", "BET1, SNARE domain [IPR039899]", "BING4, C-terminal domain [IPR012952]", "BOP1, N-terminal domain [IPR012953]", "BP28, C-terminal domain [IPR012954]", "BRCT domain [IPR001357]", "BRK domain [IPR006576]", "BRO1 domain [IPR004328]", "BSD domain [IPR005607]", "BTB/Kelch-associated [IPR011705]", "BTB/POZ domain [IPR000210]", "BURAN domain [IPR045354]", "BZW1/2, W2 domain [IPR043510]", "Bacterial Ig-like, group 2 [IPR003343]", "Bacterial surface antigen (D15) [IPR000184]", "Band 4.1 domain [IPR019749]", "Band 4.1, C-terminal [IPR008379]", "Band 7 domain [IPR001107]", "Band 7, C-terminal extension [IPR032435]", "Bap31/Bap29 cytoplasmic coiled-coil domain [IPR041672]", "Beta-Casp domain [IPR022712]", "Beta-adaptin appendage, C-terminal subdomain [IPR015151]", "Beta-catenin-like protein 1, N-terminal [IPR013180]", "Beta-galactosidase jelly roll domain [IPR025300]", "Beta-hexosaminidase, eukaryotic type, N-terminal [IPR029019]", "Beta-ketoacyl synthase, C-terminal [IPR014031]", "Beta-ketoacyl synthase, N-terminal [IPR014030]", "Bifunctional delta 1-pyrroline-5-carboxylate synthetase, glutamate-5-kinase domain [IPR041744]", "Biliverdin reductase, catalytic [IPR015249]", "Bin3-type S-adenosyl-L-methionine binding domain [IPR024160]", "Biotin carboxylase, C-terminal [IPR005482]", "Biotin carboxylase-like, N-terminal domain [IPR005481]", "Biotin carboxylation domain [IPR011764]", "Biotin protein ligase, C-terminal [IPR003142]", "Biotin-protein ligase, N-terminal [IPR019197]", "Biotin/lipoyl attachment [IPR000089]", "Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain [IPR004143]", "Bms1/Tsr1-type G domain [IPR030387]", "Borealin, N-terminal [IPR018851]", "Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal [IPR018955]", "Brdt, bromodomain, repeat I [IPR043508]", "Brdt, bromodomain, repeat II [IPR043509]", "Brix domain [IPR007109]", "Bromo adjacent homology (BAH) domain [IPR001025]", "Bromodomain [IPR001487]", "Bromodomain adjacent to zinc finger domain protein 1A, bromodomain [IPR037325]", "Brr2, N-terminal helicase PWI domain [IPR041094]", "Butyrophylin-like, SPRY domain [IPR003879]", "C-CAP/cofactor C-like domain [IPR017901]", "C-terminal associated domain of TOPRIM [IPR031660]", "C2 domain [IPR000008]", "C2 phosphatidylinositol 3-kinase-type domain [IPR002420]", "C2CD5, C2 domain [IPR037785]", "C4-type zinc-finger of DNA polymerase delta [IPR025687]", "CAAX prenyl protease 1, N-terminal [IPR032456]", "CAP Gly-rich domain [IPR000938]", "CARD domain [IPR001315]", "CARG-binding factor, N-terminal [IPR012956]", "CARP motif [IPR006599]", "CASK, SH3 domain [IPR035473]", "CBS domain [IPR000644]", "CCAAT-binding factor [IPR005612]", "CCR4-NOT transcription complex subunit 1, CAF1-binding domain [IPR032191]", "CCR4-NOT transcription complex subunit 1, HEAT repeat [IPR032194]", "CCR4-NOT transcription complex subunit 1, TTP binding domain [IPR032193]", "CCR4-NOT transcription complex subunit 1, domain 4 [IPR024557]", "CCR4-Not complex component, Not1, C-terminal [IPR007196]", "CD2-associated protein, first SH3 domain [IPR035775]", "CD2-associated protein, second SH3 domain [IPR035776]", "CD2-associated protein, third SH3 domain [IPR035777]", "CD47 immunoglobulin-like [IPR013270]", "CD47 transmembrane [IPR013147]", "CDC48, N-terminal subdomain [IPR003338]", "CDC48, domain 2 [IPR004201]", "CDH1/2, SANT-Helical linker 1 [IPR040793]", "CELF1/2, RNA recognition motif 1 [IPR034196]", "CELF1/2, RNA recognition motif 2 [IPR034198]", "CELF1/2, RNA recognition motif 3 [IPR034199]", "CENP-T/Histone H4, histone fold [IPR035425]", "CENP-V/GFA domain [IPR006913]", "CEP170, C-terminal [IPR029300]", "CFA20 domain [IPR007714]", "CHCH [IPR010625]", "CHD subfamily II, SANT-like domain [IPR009462]", "CHD, C-terminal 2 [IPR012957]", "CHD, N-terminal [IPR012958]", "CHIP, N-terminal tetratricopeptide repeat domain [IPR041312]", "CHIP/LubX , U box domain [IPR045202]", "CHORD domain [IPR007051]", "CID domain [IPR006569]", "CIDE-N domain [IPR003508]", "CLASP N-terminal domain [IPR024395]", "CLU central domain [IPR033646]", "CLU domain [IPR025697]", "CNNM, transmembrane domain [IPR002550]", "COMM domain [IPR017920]", "COP9 signalosome complex subunit 4, helix turn helix domain [IPR041406]", "COS domain [IPR017903]", "CPH domain [IPR021097]", "CPL domain [IPR012959]", "CPPED1, metallophosphatase domain [IPR041867]", "CPSF2, metallo-hydrolase domain [IPR035639]", "CPSF7, RNA recognition motif [IPR034773]", "CRA domain [IPR013144]", "CRAL-TRIO lipid binding domain [IPR001251]", "CRIB domain [IPR000095]", "CRK, C-terminal SH3 domain [IPR035458]", "CRK, N-terminal SH3 domain [IPR035457]", "CS domain [IPR007052]", "CSK-like, SH2 domain [IPR035027]", "CSN8/PSMD8/EIF3K [IPR033464]", "CTLH, C-terminal LisH motif [IPR006595]", "CTLH/CRA C-terminal to LisH motif domain [IPR024964]", "CTP synthase GATase domain [IPR033828]", "CTP synthase, N-terminal [IPR017456]", "CYRIA/CYRIB, Rac1 binding domain [IPR009828]", "Cadherin-like [IPR002126]", "Calcineurin-like phosphoesterase domain, ApaH type [IPR004843]", "Calcineurin-like phosphoesterase domain, lpxH-type [IPR024654]", "Calcium uniporter protein, C-terminal [IPR006769]", "Calcyclin-binding Protein, CS domain [IPR037893]", "Calpain subdomain III [IPR033883]", "Calponin homology domain [IPR001715]", "Caprin-1 dimerization domain [IPR041637]", "Carbamoyl-phosphate synthase large subunit, CPSase domain [IPR005483]", "Carbamoyl-phosphate synthase small subunit, GATase1 domain [IPR035686]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain [IPR002474]", "Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain [IPR005479]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain [IPR005480]", "Carbohydrate kinase PfkB [IPR011611]", "Carboxylase, conserved domain [IPR003379]", "Carboxypeptidase D, carboxypeptidase-like domain 2 [IPR034224]", "Carboxypeptidase D, carboxypeptidase-like domain 3 [IPR033848]", "Caspase recruitment domain [IPR031964]", "Cathepsin C [IPR039412]", "Cathepsin C exclusion [IPR014882]", "Cation-transporting P-type ATPase, C-terminal [IPR006068]", "Cation-transporting P-type ATPase, N-terminal [IPR004014]", "Cdc23 [IPR007192]", "Cdc37, C-terminal [IPR013873]", "Cdc37, Hsp90 binding [IPR013874]", "Cdc37, N-terminal domain [IPR013855]", "Cell division control protein 73, C-terminal [IPR031336]", "Cellular tumor antigen p53, transactivation domain 2 [IPR040926]", "Centrosomal CEP44 domain [IPR029157]", "Chaperone DnaJ, C-terminal [IPR002939]", "Chitinase II [IPR011583]", "Choline/carnitine acyltransferase domain [IPR039551]", "Choloylglycine hydrolase/NAAA C-terminal [IPR029132]", "Chromatin assembly factor 1 subunit B, C-terminal domain [IPR029129]", "Chromatin assembly factor 1 subunit p150, C-terminal [IPR029105]", "Chromatin assembly factor 1 subunit p150, N-terminal [IPR029091]", "Chromatin target of PRMT1 protein, C-terminal [IPR025715]", "Chromo domain [IPR023780]", "Chromo domain subgroup [IPR017984]", "Chromo shadow domain [IPR008251]", "Chromo/chromo shadow domain [IPR000953]", "Chromosome passenger complex (CPC) protein INCENP N-terminal [IPR022006]", "Chromosome segregation protein Spc25, C-terminal [IPR013255]", "Circularly permuted (CP)-type guanine nucleotide-binding (G) domain [IPR030378]", "Class I myosin tail homology domain [IPR010926]", "Class I myosin, motor domain [IPR036072]", "Class II PurE [IPR033626]", "Class II aldolase/adducin N-terminal [IPR001303]", "Class VI myosin, motor domain [IPR036114]", "Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain [IPR003164]", "Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain [IPR008152]", "Clathrin, heavy chain, linker, core motif [IPR015348]", "Clathrin/coatomer adaptor, adaptin-like, N-terminal [IPR002553]", "Cleavage and polyadenylation specificity factor 2, C-terminal [IPR025069]", "Cleavage stimulation factor subunit 1, dimerisation domain [IPR032028]", "Cleavage stimulation factor subunit 2, hinge domain [IPR025742]", "Cleavage/polyadenylation specificity factor, A subunit, C-terminal [IPR004871]", "Cleavage/polyadenylation specificity factor, A subunit, N-terminal [IPR018846]", "Clp ATPase, C-terminal [IPR019489]", "Clp1, N-terminal beta-sandwich domain [IPR032324]", "Clustered mitochondria protein, N-terminal [IPR028275]", "Cns1/TTC4, wheel domain [IPR044059]", "CoA-binding [IPR003781]", "Coatomer beta subunit, C-terminal [IPR011710]", "Coatomer beta subunit, appendage platform domain [IPR029446]", "Coatomer subunit gamma, C-terminal [IPR032154]", "Coatomer, WD associated region [IPR006692]", "Coatomer, alpha subunit, C-terminal [IPR010714]", "Coatomer, gamma subunit, appendage, Ig-like subdomain [IPR013040]", "Cobalamin (vitamin B12)-binding domain [IPR006158]", "Cobalamin adenosyltransferase-like [IPR016030]", "Coilin, N-terminal domain [IPR031722]", "Cold shock domain [IPR011129]", "Cold-shock (CSD) domain [IPR019844]", "Cold-shock protein, DNA-binding [IPR002059]", "Complex 1 LYR protein domain [IPR008011]", "Condensin II complex subunit H2, N-terminal [IPR009378]", "Condensin II complex subunit H2, middle domain [IPR031719]", "Condensin complex subunit 1, C-terminal [IPR032682]", "Condensin complex subunit 1, N-terminal [IPR024324]", "Condensin-2 complex subunit H2, C-terminal [IPR031737]", "Cop9 signalosome subunit 5 C-terminal domain [IPR040961]", "Copine, C-terminal [IPR010734]", "Copine, C2B domain [IPR037768]", "Core histone macro-H2A, macro domain [IPR035796]", "Cortactin, SH3 domain [IPR035716]", "Creatinase, N-terminal [IPR000587]", "Cro/C1-type helix-turn-helix domain [IPR001387]", "Cullin homology domain [IPR016158]", "Cullin protein, neddylation domain [IPR019559]", "Cullin, N-terminal [IPR001373]", "Cwf19-like protein, C-terminal domain-2 [IPR006767]", "Cwf19-like, C-terminal domain-1 [IPR006768]", "Cyclic nucleotide-binding domain [IPR000595]", "Cyclin, C-terminal domain [IPR004367]", "Cyclin, N-terminal [IPR006671]", "Cyclin-like [IPR013763]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain [IPR002130]", "Cystatin domain [IPR000010]", "Cytidyltransferase-like domain [IPR004821]", "Cytochrome C oxidase subunit II, transmembrane domain [IPR011759]", "Cytochrome b-c1 complex subunit Rieske, transmembrane domain [IPR004192]", "Cytochrome b5-like heme/steroid binding domain [IPR001199]", "Cytochrome c oxidase assembly factor 3, mitochondrial, coiled-coil domain [IPR018628]", "Cytochrome c oxidase subunit 2, C-terminal [IPR034210]", "Cytochrome c oxidase subunit II-like C-terminal [IPR002429]", "Cytochrome c oxidase, subunit II [IPR014222]", "Cytoplasmic activation/proliferation-associated protein-1 C term [IPR022070]", "Cytoskeleton-associated protein 2, C-terminal [IPR029197]", "Cytosolic fatty-acid binding [IPR000463]", "D-3-phosphoglycerate dehydrogenase, ASB domain [IPR045626]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain [IPR006140]", "D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain [IPR006139]", "DALR anticodon binding [IPR008909]", "DAZ-associated protein 1, RNA recognition motif 1 [IPR034134]", "DAZ-associated protein 1, RNA recognition motif 2 [IPR034131]", "DBC1/CARP1 catalytically inactive NUDIX hydrolase domain [IPR025954]", "DBINO domain [IPR020838]", "DBP10, C-terminal [IPR012541]", "DDE superfamily endonuclease domain [IPR004875]", "DDHD domain [IPR004177]", "DDT domain [IPR018501]", "DDX18/Has1, DEAD-box helicase domain [IPR044773]", "DDX41, DEAD-box helicase domain [IPR044113]", "DDX47/Rrp3, DEAD-box helicase domain [IPR044765]", "DDX52/Rok1, DEAD-box helicase domain [IPR044764]", "DEAD box protein 17, ATP-binding domain [IPR046330]", "DEAD/DEAH box helicase domain [IPR011545]", "DEAD2 [IPR010614]", "DEK, C-terminal [IPR014876]", "DET1- and DDB1-associated protein 1, N-terminal [IPR018276]", "DEUBAD domain [IPR044867]", "DExH-box ATP-dependent RNA helicase, R3H domain [IPR034083]", "DFDF domain [IPR025762]", "DHHA1 domain [IPR003156]", "DHX15, DEXH-box helicase domain [IPR044756]", "DHX8/ Prp22, DEXH-box helicase domain [IPR044762]", "DHX9, DEXH-box helicase domain [IPR044447]", "DHX9, first double-stranded RNA binding domain [IPR044445]", "DHX9, second double-stranded RNA binding domain [IPR044446]", "DIS3-like exonuclease 2, C-terminal [IPR041093]", "DJ-1/PfpI [IPR002818]", "DMAP1-binding domain [IPR010506]", "DML1/Misato, tubulin domain [IPR029209]", "DNA (cytosine-5)-methyltransferase 1, replication foci domain [IPR022702]", "DNA damage inducible protein 1 ubiquitin-like domain [IPR033882]", "DNA fragmentation factor 45kDa, middle domain [IPR015121]", "DNA helicase, DnaB-like, C-terminal [IPR007694]", "DNA ligase 3, BRCT domain [IPR031916]", "DNA ligase, ATP-dependent, C-terminal [IPR012309]", "DNA ligase, ATP-dependent, N-terminal [IPR012308]", "DNA ligase, ATP-dependent, central [IPR012310]", "DNA mismatch repair protein MutS, C-terminal [IPR000432]", "DNA mismatch repair protein MutS, clamp [IPR007861]", "DNA mismatch repair protein MutS, connector domain [IPR007860]", "DNA mismatch repair protein MutS, core [IPR007696]", "DNA mismatch repair protein MutS-like, N-terminal [IPR007695]", "DNA polymerase alpha catalytic subunit, N-terminal domain [IPR024647]", "DNA polymerase alpha catalytic subunit, catalytic domain [IPR045846]", "DNA polymerase alpha, subunit B, N-terminal [IPR013627]", "DNA polymerase alpha/delta/epsilon, subunit B [IPR007185]", "DNA polymerase epsilon, catalytic subunit A, C-terminal [IPR013697]", "DNA repair Nbs1, C-terminal [IPR013908]", "DNA replication complex GINS protein SLD5, C-terminal [IPR031633]", "DNA replication factor RFC1, C-terminal [IPR013725]", "DNA topoisomerase 2, TOPRIM domain [IPR034157]", "DNA topoisomerase I, DNA binding, eukaryotic-type [IPR008336]", "DNA topoisomerase I, catalytic core, eukaryotic-type [IPR013500]", "DNA topoisomerase I, eukaryotic-type [IPR013499]", "DNA topoisomerase, type IIA, domain A [IPR002205]", "DNA topoisomerase, type IIA, subunit B, domain 2 [IPR013506]", "DNA-dependent protein kinase catalytic subunit, CC3 [IPR012582]", "DNA-dependent protein kinase catalytic subunit, CC5 [IPR045581]", "DNA-dependent protein kinase catalytic subunit, catalytic domain [IPR037706]", "DNA-directed DNA polymerase, family B, exonuclease domain [IPR006133]", "DNA-directed DNA polymerase, family B, multifunctional domain [IPR006134]", "DNA-directed RNA polymerase I subunit RPA2, domain 4 [IPR009674]", "DNA-directed RNA polymerase III subunit RPC1, C-terminal [IPR035698]", "DNA-directed RNA polymerase III subunit RPC1, N-terminal [IPR035697]", "DNA-directed RNA polymerase, N-terminal [IPR029262]", "DNA-directed RNA polymerase, RpoA/D/Rpb3-type [IPR011263]", "DNA-directed RNA polymerase, insert domain [IPR011262]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain [IPR007120]", "DNA-repair protein Xrcc1, N-terminal [IPR002706]", "DNA/RNA non-specific endonuclease [IPR001604]", "DNA/RNA-binding protein Alba-like [IPR002775]", "DNA2/NAM7 helicase, helicase domain [IPR041677]", "DNA2/NAM7 helicase-like, C-terminal [IPR041679]", "DPF1-3, N-terminal domain [IPR025750]", "DSBA-like thioredoxin domain [IPR001853]", "DTHCT [IPR012542]", "DWNN domain [IPR014891]", "DZF domain [IPR006561]", "Damage-control phosphatase ARMT1-like, metal-binding domain [IPR002791]", "Daxx, N-terminal Rassf1C-interacting domain [IPR031333]", "Dbl homology (DH) domain [IPR000219]", "Death domain [IPR000488]", "Dehydrogenase, E1 component [IPR001017]", "Deoxynucleoside kinase domain [IPR031314]", "Desmoplakin, SH3 domain [IPR041615]", "Desmoplakin, spectrin-like domain [IPR041573]", "Deubiquitinating enzyme MINDY-3/4, conserved domain [IPR025257]", "Diacylglycerol kinase, catalytic domain [IPR001206]", "Diaphanous autoregulatory (DAD) domain [IPR014767]", "Dicer dimerisation domain [IPR005034]", "Dicer, double-stranded RNA-binding domain [IPR044441]", "Dihydrofolate reductase domain [IPR001796]", "Dilute domain [IPR002710]", "Dip2-like domain [IPR037337]", "Dipeptidyl peptidase 8 /9 ,N-terminal [IPR045785]", "Dipeptidylpeptidase IV, N-terminal domain [IPR002469]", "Dis3-like cold-shock domain 2 [IPR041505]", "Disulphide isomerase [IPR005788]", "DnaJ domain [IPR001623]", "DnaJ-like protein C11, C-terminal [IPR024586]", "Domain of unknown function DUF1087 [IPR009463]", "Domain of unknown function DUF1115 [IPR010541]", "Domain of unknown function DUF1605 [IPR011709]", "Domain of unknown function DUF1731 [IPR013549]", "Domain of unknown function DUF1747 [IPR013719]", "Domain of unknown function DUF1899 [IPR015048]", "Domain of unknown function DUF3350 [IPR021785]", "Domain of unknown function DUF3385, target of rapamycin protein [IPR024585]", "Domain of unknown function DUF3456 [IPR021852]", "Domain of unknown function DUF3480 [IPR022557]", "Domain of unknown function DUF3517 [IPR021905]", "Domain of unknown function DUF382 [IPR007180]", "Domain of unknown function DUF4149 [IPR025423]", "Domain of unknown function DUF4208 [IPR025260]", "Domain of unknown function DUF4217 [IPR025313]", "Domain of unknown function DUF4749 [IPR031847]", "Domain of unknown function DUF5600 [IPR040990]", "Double-stranded RNA-binding domain [IPR014720]", "Down-regulated-in-metastasis protein [IPR011430]", "Drebrin-like protein, SH3 domain [IPR035717]", "Drought induced 19 protein type, zinc-binding domain [IPR008598]", "Dual specificity phosphatase, catalytic domain [IPR000340]", "Dual specificity protein phosphatase domain [IPR020422]", "Dynamin GTPase effector [IPR003130]", "Dynamin stalk domain [IPR000375]", "Dynamin, GTPase domain [IPR001401]", "Dynamin, N-terminal [IPR045063]", "Dynamin-like GTPase OPA1, C-terminal [IPR045817]", "Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]", "Dynein associated protein [IPR022157]", "Dynein heavy chain AAA lid domain [IPR041658]", "Dynein heavy chain region D6 P-loop domain [IPR004273]", "Dynein heavy chain, AAA 5 extension domain [IPR041466]", "Dynein heavy chain, AAA module D4 [IPR024317]", "Dynein heavy chain, ATP-binding dynein motor region [IPR035706]", "Dynein heavy chain, C-terminal domain [IPR041228]", "Dynein heavy chain, coiled coil stalk [IPR024743]", "Dynein heavy chain, hydrolytic ATP-binding dynein motor region [IPR035699]", "Dynein heavy chain, linker [IPR013602]", "Dynein heavy chain, tail [IPR013594]", "Dyskerin-like [IPR012960]", "E2 binding [IPR014929]", "E3 ligase, CCCH-type zinc finger [IPR041367]", "E3 ubiquitin ligase EDD, ubiquitin-associated domain [IPR024725]", "E3 ubiquitin ligase UBR4, C-terminal [IPR025704]", "E3 ubiquitin ligase, domain of unknown function DUF908 [IPR010309]", "E3 ubiquitin ligase, domain of unknown function DUF913 [IPR010314]", "E3 ubiquitin-protein ligase RNF114, RING finger, HC subclass [IPR042716]", "E3 ubiquitin-protein ligase UBR4, N-terminal [IPR045841]", "EB1, C-terminal [IPR004953]", "EBP50, C-terminal [IPR015098]", "ECSIT, C-terminal domain [IPR029342]", "EF hand associated, type-1 [IPR013566]", "EF hand associated, type-2 [IPR013567]", "EF-hand domain [IPR002048]", "EF-hand domain, type 1 [IPR015153]", "EF-hand domain, type 2 [IPR015154]", "EF-hand, Ca insensitive [IPR014837]", "EFG, domain V [IPR035649]", "EGF-like domain, extracellular [IPR013111]", "EH domain [IPR000261]", "EH domain-containing protein, N-terminal [IPR031692]", "EIF2AK2, first double-stranded RNA binding domain [IPR044452]", "EIF2AK2, second double-stranded RNA binding domain [IPR044453]", "ELM2 domain [IPR000949]", "ELMO domain [IPR006816]", "ELMO, armadillo-like helical domain [IPR024574]", "ENTH domain [IPR013809]", "ER membrane protein complex subunit 1, C-terminal [IPR011678]", "ER membrane protein complex subunit 7, beta-sandwich domain [IPR019008]", "ERAP1-like C-terminal domain [IPR024571]", "ERM family, FERM domain C-lobe [IPR041789]", "ERV/ALR sulfhydryl oxidase domain [IPR017905]", "ERdj5, C-terminal thioredoxin domain [IPR035674]", "ERdj5, first thioredoxin domain [IPR035673]", "ERp29, N-terminal [IPR012883]", "EWS, RNA recognition motif [IPR034869]", "EXPERA domain [IPR033118]", "EYA domain [IPR006545]", "EYA domain, metazoan [IPR042577]", "Electron transfer flavoprotein, alpha subunit, C-terminal [IPR014731]", "Electron transfer flavoprotein, alpha subunit, N-terminal [IPR033947]", "Electron transfer flavoprotein, alpha/beta-subunit, N-terminal [IPR014730]", "Electron transfer flavoprotein, beta subunit, N-terminal [IPR033948]", "Elongation Factor G, domain II [IPR041095]", "Elongation factor 1 beta central acidic region, eukaryote [IPR018940]", "Elongation factor 1B gamma, C-terminal [IPR001662]", "Elongation factor EFG, domain V-like [IPR000640]", "Elongation factor G, domain III [IPR009022]", "Elongation factor Tu (EF-Tu), GTP-binding domain [IPR041709]", "Elongation factor Tu, domain 2 [IPR033720]", "Elp3/MiaB/NifB [IPR006638]", "Emerin, LEM domain [IPR034989]", "Endonuclease/exonuclease/phosphatase [IPR005135]", "Endophilin B2, SH3 domain [IPR035640]", "Endophilin-A, SH3 domain [IPR035824]", "Endophilin-B1, BAR domain [IPR035695]", "Endoplasmic reticulum resident protein 29, C-terminal [IPR011679]", "Endoplasmic reticulum resident protein 44, TRX-like domain b [IPR041870]", "Endoplasmic reticulum resident protein 44, TRX-like domain b' [IPR041862]", "Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]", "Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]", "Enhancer of mRNA-decapping protein 4, WD40 repeat region [IPR032401]", "Enolase, C-terminal TIM barrel domain [IPR020810]", "Enolase, N-terminal [IPR020811]", "Enoyl-CoA hydratase/isomerase domain [IPR045004]", "Era-type guanine nucleotide-binding (G) domain [IPR030388]", "Eukaryotic Ribosomal Protein L27, KOW domain [IPR041991]", "Eukaryotic glycogen debranching enzyme, N-terminal domain [IPR029436]", "Eukaryotic translation initiation factor 2D, SUI1 domain [IPR039759]", "Eukaryotic translation initiation factor 3 subunit E, N-terminal [IPR019010]", "Eukaryotic translation initiation factor 3 subunit G, N-terminal [IPR024675]", "Exocyst complex component EXOC2/Sec5, N-terminal domain [IPR039481]", "Exonuclease 1-like, PIN-like domain [IPR044752]", "Exonuclease, RNase T/DNA polymerase III [IPR013520]", "Exonuclease-1, H3TH domain [IPR037315]", "Exoribonuclease, phosphorolytic domain 1 [IPR001247]", "Exoribonuclease, phosphorolytic domain 2 [IPR015847]", "Exosome complex component, N-terminal domain [IPR025721]", "Exosome complex exonuclease RRP44, S1 domain [IPR033770]", "Exosome-associated factor Rrp6, N-terminal [IPR012588]", "Exportin-1, C-terminal [IPR014877]", "Exportin-1/Importin-beta-like [IPR013598]", "Exportin-2, C-terminal [IPR005043]", "Exportin-2, central domain [IPR013713]", "Exportin-5, C-terminal domain [IPR045478]", "Exportin-T, C-terminal domain [IPR045546]", "Extended PHD (ePHD) domain [IPR034732]", "Extended synaptotagmin, C-terminal C2 domain [IPR037752]", "Extended synaptotagmin, C2A domain [IPR037733]", "Extended synaptotagmin, C2B domain [IPR037749]", "Extracellular Endonuclease, subunit A [IPR020821]", "F-BAR domain [IPR031160]", "F-box domain [IPR001810]", "FACT complex subunit POB3-like, N-terminal PH domain [IPR035417]", "FACT complex subunit Spt16 domain [IPR013953]", "FACT complex subunit Spt16, N-terminal lobe domain [IPR029148]", "FACT complex subunit Spt16, peptidase M24-like domain [IPR033825]", "FAD dependent oxidoreductase [IPR006076]", "FAD linked oxidase, N-terminal [IPR006094]", "FAD-binding domain, PCMH-type [IPR016166]", "FAD-binding domain, ferredoxin reductase-type [IPR017927]", "FAD-dependent oxidoreductase 2, FAD binding domain [IPR003953]", "FAD-linked oxidase, C-terminal [IPR004113]", "FAD/NAD(P)-binding domain [IPR023753]", "FAF1, UBA-like domain [IPR044541]", "FAM3C (ILEI) domain [IPR039475]", "FAM91, C-terminal domain [IPR028097]", "FAM91, N-terminal domain [IPR028091]", "FANCI helical domain 1 [IPR029310]", "FANCI helical domain 2 [IPR029312]", "FANCI solenoid 1 cap [IPR029305]", "FANCI solenoid 1 domain [IPR029308]", "FANCI solenoid 2 domain [IPR029315]", "FANCI solenoid 3 domain [IPR029313]", "FANCI solenoid 4 domain [IPR029314]", "FAS-associated factor 1-like, UBX domain [IPR033043]", "FAST kinase leucine-rich [IPR010622]", "FAST kinase-like protein, subdomain 2 [IPR013579]", "FATC domain [IPR003152]", "FCH domain [IPR001060]", "FCP1 homology domain [IPR004274]", "FDF domain [IPR019050]", "FERM adjacent (FA) [IPR014847]", "FERM central domain [IPR019748]", "FERM domain [IPR000299]", "FERM, C-terminal PH-like domain [IPR018980]", "FERM, N-terminal [IPR018979]", "FF domain [IPR002713]", "FFD box [IPR025761]", "FGFR1 oncogene partner (FOP), N-terminal dimerisation domain [IPR018993]", "FHOD1, N-terminal GTPase-binding domain [IPR041387]", "FIST, C-domain [IPR019494]", "FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]", "FKBP12-rapamycin binding domain [IPR009076]", "FKBP3, basic tilted helix bundle domain [IPR041200]", "FY-rich, C-terminal [IPR003889]", "FY-rich, N-terminal [IPR003888]", "FYVE zinc finger [IPR000306]", "Far upstream element-binding protein, C-terminal [IPR015096]", "Fascin domain [IPR022768]", "Fatty acid desaturase domain [IPR005804]", "Fatty acid hydroxylase [IPR006694]", "Fatty acyl-CoA reductase, C-terminal [IPR033640]", "Fatty acyl-coenzyme A reductase, NAD-binding domain [IPR013120]", "Fcf2 pre-rRNA processing, C-terminal [IPR014810]", "Ferrochelatase, C-terminal [IPR033644]", "Ferrochelatase, N-terminal [IPR033659]", "Fibronectin type II domain [IPR000562]", "Fibronectin type III [IPR003961]", "First polo-box domain [IPR033701]", "Flavodoxin-like [IPR001094]", "Flavodoxin/nitric oxide synthase [IPR008254]", "Flavoprotein pyridine nucleotide cytochrome reductase [IPR001709]", "Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain [IPR008333]", "Folliculin, DENN domain [IPR032035]", "Folliculin/SMCR8, longin domain [IPR037520]", "Folliculin/SMCR8, tripartite DENN domain [IPR037521]", "Fork head domain [IPR001766]", "Forkhead-associated (FHA) domain [IPR000253]", "Formin, FH2 domain [IPR015425]", "Formin, FH3 domain [IPR010472]", "Formin, GTPase-binding domain [IPR010473]", "Formyl transferase, N-terminal [IPR002376]", "Fragile X-related 1 protein, C-terminal core [IPR022034]", "Fragile X-related 1 protein, C-terminal region 1 [IPR032172]", "Fragile X-related 1 protein, C-terminal region 3 [IPR032177]", "Fragile X-related mental retardation protein, C-terminal region 2 [IPR032196]", "Fumarase C, C-terminal [IPR018951]", "Fumarate lyase, N-terminal [IPR022761]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal [IPR015939]", "Fumarylacetoacetase, N-terminal [IPR015377]", "Fumarylacetoacetase-like, C-terminal [IPR011234]", "Furin-like cysteine-rich domain [IPR006211]", "Fxr1, tudor domain [IPR041560]", "Fzo/mitofusin HR2 domain [IPR006884]", "G-patch domain [IPR000467]", "G-patch domain and KOW motifs-containing protein, KOW 1 [IPR041993]", "G-patch domain and KOW motifs-containing protein, KOW 2 [IPR041994]", "G-protein gamma-like domain [IPR015898]", "G-protein, beta subunit [IPR001632]", "G3BP1, RNA recognition motif [IPR034374]", "G3BP2, RNA recognition motif [IPR034376]", "GAD domain [IPR029351]", "GAR domain [IPR003108]", "GB1/RHD3-type guanine nucleotide-binding (G) domain [IPR030386]", "GCC2, Rab binding domain [IPR032023]", "GCF, C-terminal [IPR022783]", "GHMP kinase N-terminal domain [IPR006204]", "GHMP kinase, C-terminal domain [IPR013750]", "GINS complex protein Sld5, alpha-helical domain [IPR038749]", "GINS subunit, domain A [IPR021151]", "GMP phosphodiesterase, delta subunit [IPR008015]", "GMP synthase, C-terminal [IPR001674]", "GMP synthase, glutamine amidotransferase [IPR004739]", "GMP synthetase ATP pyrophosphatase domain [IPR025777]", "GNAT domain [IPR000182]", "GOLD domain [IPR009038]", "GPR domain [IPR000965]", "GRAM domain [IPR004182]", "GRB2, C-terminal SH3 domain [IPR035643]", "GRB2, N-terminal SH3 domain [IPR035641]", "GRIP domain [IPR000237]", "GRSF-1, RNA recognition motif 1 [IPR034425]", "GRSF-1, RNA recognition motif 2 [IPR034424]", "GRSF-1, RNA recognition motif 3 [IPR034426]", "GTP binding domain [IPR006073]", "GTP binding protein 1-like, GTP-binding domain [IPR035531]", "GTP binding protein, second domain [IPR031662]", "GTP1/OBG domain [IPR006169]", "GTPase effector domain [IPR020850]", "GUCT [IPR012562]", "GYF domain [IPR003169]", "Galactokinase, N-terminal domain [IPR019539]", "Galactose mutarotase, N-terminal barrel [IPR031727]", "Galectin, carbohydrate recognition domain [IPR001079]", "Gamma tubulin complex component protein, N-terminal [IPR041470]", "Gamma tubulin complex component, C-terminal [IPR040457]", "Gamma-adaptin ear (GAE) domain [IPR008153]", "Gamma-glutamyl cyclotransferase-like [IPR013024]", "Gcp-like domain [IPR000905]", "Gelsolin-like domain [IPR007123]", "Gfo/Idh/MocA-like oxidoreductase, N-terminal [IPR000683]", "GlmS/AgaS, SIS domain 1 [IPR035466]", "GlmS/FrlB, SIS domain 2 [IPR035490]", "Glucosamine/galactosamine-6-phosphate isomerase [IPR006148]", "Glucose-6-phosphate dehydrogenase, C-terminal [IPR022675]", "Glucose-6-phosphate dehydrogenase, NAD-binding [IPR022674]", "Glucosidase 2 subunit beta-like [IPR036607]", "Glucosidase II beta subunit, N-terminal [IPR028146]", "Glucosyltransferase 24, catalytic domain [IPR040497]", "Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal [IPR006096]", "Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain [IPR006097]", "Glutaminase, EF-hand domain [IPR041541]", "Glutamine amidotransferase [IPR017926]", "Glutamine amidotransferase type 2 domain [IPR017932]", "Glutamine-Leucine-Glutamine, QLQ [IPR014978]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain 2 [IPR007638]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal [IPR007639]", "Glutamyl-tRNA synthetase [IPR033910]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain [IPR020059]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain [IPR020058]", "Glutaredoxin [IPR002109]", "Glutaredoxin, PICOT-like [IPR033658]", "Glutathione S-transferase, C-terminal [IPR004046]", "Glutathione S-transferase, C-terminal-like [IPR010987]", "Glutathione S-transferase, N-terminal [IPR004045]", "Glutathione S-transferases, class Zeta , C-terminal [IPR034330]", "Glutathione S-transferases, class Zeta , N-terminal [IPR034333]", "Glutathione synthase, substrate-binding domain [IPR004887]", "Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain [IPR020828]", "Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain [IPR020829]", "Glycerophosphodiester phosphodiesterase domain [IPR030395]", "Glycogen debranching enzyme, C-terminal [IPR032790]", "Glycogen debranching enzyme, central domain [IPR032788]", "Glycogen debranching enzyme, glucanotransferase domain [IPR032792]", "Glycolipid transfer protein domain [IPR014830]", "Glycoside hydrolase 35, catalytic domain [IPR031330]", "Glycoside hydrolase family 18, catalytic domain [IPR001223]", "Glycoside hydrolase family 2, catalytic domain [IPR006103]", "Glycoside hydrolase family 20, catalytic domain [IPR015883]", "Glycoside hydrolase family 31, N-terminal domain [IPR025887]", "Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich [IPR006102]", "Glycosyl hydrolase family 30, TIM-barrel domain [IPR033453]", "Glycosyl hydrolase family 30, beta sandwich domain [IPR033452]", "Glycosyl hydrolase family 63, C-terminal [IPR031335]", "Glycosyl hydrolase family 63, N-terminal [IPR031631]", "Glycosyl hydrolase, family 13, catalytic domain [IPR006047]", "Glycosyl hydrolases family 2, sugar binding domain [IPR006104]", "Glycosyl transferase CAP10 domain [IPR006598]", "Glycosyl transferase, family 1 [IPR001296]", "Glycosyltransferase 2-like [IPR001173]", "Glycyl-tRNA synthetase-like core domain [IPR033731]", "Glyoxalase domain-containing protein 4, C-terminal [IPR043194]", "Glyoxalase/fosfomycin resistance/dioxygenase domain [IPR004360]", "Growth hormone-inducible transmembrane protein [IPR035871]", "Guanine nucleotide exchange factor, N-terminal [IPR032691]", "Guanine nucleotide-binding protein-like 3, N-terminal domain [IPR014813]", "Guanylate kinase-like domain [IPR008144]", "Guanylate kinase/L-type calcium channel beta subunit [IPR008145]", "Guanylate-binding protein, N-terminal [IPR015894]", "Guanylate-binding protein/Atlastin, C-terminal [IPR003191]", "HAD-superfamily hydrolase, subfamily IIID [IPR011943]", "HBS1-like protein, N-terminal [IPR015033]", "HCLS1-binding protein 3, PX domain [IPR037901]", "HD domain [IPR006674]", "HD/PDEase domain [IPR003607]", "HDGF-related, PWWP domain [IPR035496]", "HECT domain [IPR000569]", "HELLS, N-terminal [IPR044753]", "HELP [IPR005108]", "HERC2, APC10 domain [IPR037976]", "HERC2, zinc finger, ZZ-type [IPR041987]", "HHH domain 9 [IPR041692]", "HIRAN domain [IPR014905]", "HIT-like domain [IPR011146]", "HR1 rho-binding domain [IPR011072]", "HRDC domain [IPR002121]", "HSPA4, nucleotide-binding domain [IPR042052]", "HSPA4L, nucleotide-binding domain [IPR042708]", "HSPH1, nucleotide-binding domain [IPR042053]", "HTH CenpB-type DNA-binding domain [IPR006600]", "HTTM [IPR011020]", "HUWE1, UBA domain [IPR041918]", "Heat shock 70kDa protein 14, nucleotide-binding domain [IPR042049]", "Heat shock chaperonin-binding [IPR006636]", "Heat shock protein DnaJ, cysteine-rich domain [IPR001305]", "Heat shock protein Hsp90, N-terminal [IPR020575]", "Heat shock protein beta-1, ACD domain [IPR037876]", "Heavy metal-associated domain, HMA [IPR006121]", "Heavy metal-associated domain, copper ion-binding [IPR006122]", "Helical and beta-bridge domain [IPR010643]", "Helicase domain [IPR007807]", "Helicase superfamily 1/2, ATP-binding domain [IPR014001]", "Helicase superfamily 1/2, ATP-binding domain, DinG/Rad3-type [IPR014013]", "Helicase, C-terminal [IPR001650]", "Helicase-associated domain [IPR007502]", "Helicase-like, DEXD box c2 type [IPR006554]", "Helicase/SANT-associated domain [IPR014012]", "Helicase/UvrB, N-terminal [IPR006935]", "Helix-hairpin-helix DNA-binding motif, class 1 [IPR003583]", "Helix-turn-helix DNA-binding domain of Spt6 [IPR028088]", "Hemimethylated DNA-binding domain [IPR011722]", "Hepatitis delta antigen (HDAg) domain [IPR037517]", "Hepatocyte growth factor-regulated tyrosine kinase substrate, helical domain [IPR024641]", "Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 1 [IPR034544]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 2 [IPR034548]", "Heterogeneous nuclear ribonucleoprotein R, RNA recognition motif 2 [IPR034411]", "Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778]", "Hexokinase, C-terminal [IPR022673]", "Hexokinase, N-terminal [IPR022672]", "High mobility group box domain 5 [IPR029215]", "High mobility group box domain [IPR009071]", "Histidine kinase domain [IPR005467]", "Histidine kinase/HSP90-like ATPase [IPR003594]", "Histone H2A, C-terminal domain [IPR032454]", "Histone H2A/H2B/H3 [IPR007125]", "Histone acetyl transferase HAT1 N-terminal [IPR019467]", "Histone acetyltransferase domain, MYST-type [IPR002717]", "Histone deacetylase domain [IPR023801]", "Histone deacetylase interacting domain [IPR013194]", "Histone-arginine methyltransferase CARM1, N-terminal [IPR020989]", "Histone-binding protein RBBP4, N-terminal [IPR022052]", "HnRNP M, nuclear localisation signal [IPR024666]", "Homeobox domain [IPR001356]", "Hotdog acyl-CoA thioesterase (ACOT)-type domain [IPR033120]", "HuR, RNA recognition motif 2 [IPR034996]", "Hyaluronan/mRNA-binding protein [IPR006861]", "Hydroxymethylglutaryl-coenzyme A synthase, C-terminal domain [IPR013746]", "Hydroxymethylglutaryl-coenzyme A synthase, N-terminal [IPR013528]", "I-kappa-kinase-beta NEMO binding domain [IPR022007]", "I/LWEQ domain [IPR002558]", "IBR domain [IPR002867]", "IF2a, S1-like domain [IPR044126]", "IGF2BP1, RNA recognition motif 1 [IPR034837]", "IGF2BP1, RNA recognition motif 2 [IPR034842]", "IGF2BP2, RNA recognition motif 1 [IPR034843]", "IGF2BP3, RNA recognition motif 2 [IPR034844]", "IKBKB, scaffold dimerization domain [IPR041185]", "ILEI/PANDER domain [IPR039477]", "IMD/I-BAR domain [IPR013606]", "IMP dehydrogenase/GMP reductase [IPR001093]", "IPS1, CARD domain [IPR042144]", "IPT domain [IPR002909]", "IRS-type PTB domain [IPR002404]", "IRSp53, SH3 domain [IPR035594]", "ISWI, HAND domain [IPR015194]", "Immunoglobulin C1-set [IPR003597]", "Immunoglobulin I-set [IPR013098]", "Immunoglobulin V-set domain [IPR013106]", "Immunoglobulin [IPR013151]", "Immunoglobulin subtype 2 [IPR003598]", "Immunoglobulin subtype [IPR003599]", "Immunoglobulin-like domain [IPR007110]", "Importin-alpha, importin-beta-binding domain [IPR002652]", "Importin-beta, N-terminal domain [IPR001494]", "Initiation factor eIF-4 gamma, MA3 [IPR003891]", "Inner centromere protein, ARK-binding domain [IPR005635]", "Inositol 1,3,4-trisphosphate 5/6-kinase, ATP-grasp domain [IPR040464]", "Inositol polyphosphate 5-phosphatase, clathrin binding domain [IPR031995]", "Inositol polyphosphate-related phosphatase [IPR000300]", "Inositol-tetrakisphosphate 1-kinase, N-terminal [IPR041429]", "Integrator complex subunit 3, N-terminal [IPR019333]", "Integrin beta N-terminal [IPR033760]", "Integrin beta subunit, VWA domain [IPR002369]", "Integrin beta subunit, cytoplasmic domain [IPR014836]", "Integrin beta subunit, tail [IPR012896]", "Integrin beta, epidermal growth factor-like domain 1 [IPR040622]", "Interferon regulatory factor 2-binding protein 1 & 2, zinc finger [IPR022750]", "Intermediate filament head, DNA-binding domain [IPR006821]", "Intermediate filament, rod domain [IPR039008]", "Intracellular hyaluronan-binding protein 4, N-terminal domain [IPR032381]", "Intron-binding protein aquarius, N-terminal [IPR032174]", "Ion transporter-like, CBS domain [IPR044751]", "Iron sulphur domain-containing, mitoNEET, N-terminal [IPR019610]", "Iron-binding zinc finger, CDGSH type [IPR018967]", "Isochorismatase-like [IPR000868]", "Isoleucyl tRNA synthetase type 1, anticodon-binding domain [IPR033708]", "Isoleucyl tRNA synthetase type 2, anticodon-binding domain [IPR033709]", "Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain [IPR044861]", "Isopropylmalate dehydrogenase-like domain [IPR024084]", "JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]", "JNK-interacting protein, leucine zipper II [IPR032486]", "JNK/Rab-associated protein-1, N-terminal [IPR019143]", "JmjC domain [IPR003347]", "Jumonji, helical domain [IPR041070]", "K Homology domain [IPR004087]", "K Homology domain, type 1 [IPR004088]", "K Homology domain, type 2 [IPR004044]", "KASH domain [IPR012315]", "KHDRBS, Qua1 domain [IPR032571]", "KMT2A, PHD domain 1 [IPR042023]", "KMT2A, PHD domain 2 [IPR042025]", "KMT2A, PHD domain 3 [IPR044133]", "KMT2A, ePHD domain [IPR041958]", "KOW [IPR005824]", "Kinase associated domain 1 (KA1) [IPR001772]", "Kindlin-2, N-terminal [IPR040790]", "Kindlin/fermitin, PH domain [IPR037837]", "Kinesin motor domain [IPR001752]", "Kinesin-associated [IPR032405]", "Kinesin-associated microtubule-binding domain [IPR025901]", "Kinesin-like KIF1-type [IPR022140]", "Kinesin-like [IPR022164]", "Kinesin-like protein Kif23, Arf6-interacting domain [IPR032384]", "Kinetochore protein Nuf2, N-terminal [IPR005549]", "Kri1-like, C-terminal [IPR024626]", "Krr1, KH1 domain [IPR041174]", "Ku, C-terminal [IPR014893]", "Ku70/Ku80 C-terminal arm [IPR005160]", "Ku70/Ku80 beta-barrel domain [IPR006164]", "Ku70/Ku80, N-terminal alpha/beta [IPR005161]", "L27 domain [IPR004172]", "L27 domain, C-terminal [IPR014775]", "LAIKA domain [IPR045353]", "LARP4, RNA recognition motif [IPR034903]", "LARP5, RNA recognition motif [IPR034900]", "LARP7, RNA recognition motif 1 [IPR034887]", "LARP7, RNA recognition motif 2 [IPR034910]", "LEM domain [IPR003887]", "LEM-like domain [IPR013146]", "LETM1, ribosome-binding domain [IPR033122]", "LETM1-like [IPR011685]", "LIS1 homology motif [IPR006594]", "LSM domain, eukaryotic/archaea-type [IPR001163]", "LSM-interacting domain [IPR008669]", "La protein, xRRM domain [IPR014886]", "La-related protein 7, La domain [IPR034946]", "La-type HTH domain [IPR006630]", "Lactate/malate dehydrogenase, C-terminal [IPR022383]", "Lactate/malate dehydrogenase, N-terminal [IPR001236]", "Lamin tail domain [IPR001322]", "Lamin-B receptor of TUDOR domain [IPR019023]", "Lamina-associated polypeptide 2 alpha, C-terminal [IPR021623]", "Large proline-rich protein BAG6 [IPR021925]", "Lasp1, SH3 domain [IPR035630]", "Legume-like lectin [IPR005052]", "Lens epithelium-derived growth factor, integrase-binding domain [IPR021567]", "Lethal giant larvae homologue 2 [IPR013577]", "Leucine zipper, homeobox-associated [IPR003106]", "Leukocyte surface antigen CD47, IgV [IPR037805]", "Linker histone H1/H5, domain H15 [IPR005818]", "Lipocalin/cytosolic fatty-acid binding domain [IPR000566]", "Listerin, zinc finger, RING-type [IPR039804]", "Lon, substrate-binding domain [IPR003111]", "Longin domain [IPR010908]", "Lsm14-like, N-terminal [IPR025609]", "Lsm16, N-terminal [IPR034107]", "LsmAD domain [IPR009604]", "Lysine-tRNA ligase, class II, N-terminal [IPR044136]", "Lysophosphatidylcholine acyltransferase LPCAT1-like [IPR045252]", "Lysyl-tRNA synthetase, class II, C-terminal [IPR018149]", "M60-like domain, N-terminal [IPR035423]", "MAGE homology domain [IPR002190]", "MAN1, RNA recognition motif [IPR034394]", "MATH/TRAF domain [IPR002083]", "MCM N-terminal domain [IPR027925]", "MCM OB domain [IPR033762]", "MCM domain [IPR001208]", "MCM, AAA-lid domain [IPR041562]", "MD-2-related lipid-recognition domain [IPR003172]", "MDM2-binding protein, N-terminal domain [IPR029421]", "MDM2-binding protein, central domain [IPR029420]", "MDN2-binding protein, C-terminal domain [IPR029418]", "MEF-2, RNA recognition motif 1 [IPR034630]", "MEF-2, RNA recognition motif 3 [IPR034631]", "MENTAL domain [IPR019498]", "MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]", "MHC class I, alpha chain, C-terminal [IPR010579]", "MHC class I-like antigen recognition-like [IPR011161]", "MIF4G-like, type 1 [IPR015172]", "MIF4G-like, type 2 [IPR015174]", "MIF4G-like, type 3 [IPR003890]", "MIRO domain [IPR020860]", "MIT domain [IPR007330]", "MKI67 FHA domain-interacting nucleolar phosphoprotein, FHA Ki67 binding [IPR021043]", "MMS19, C-terminal [IPR024687]", "MMS19, N-terminal [IPR029240]", "MOSC, N-terminal beta barrel [IPR005303]", "MPN domain [IPR037518]", "MPP2, SH3 domain [IPR035602]", "MPP6, SH3 domain [IPR035603]", "MRG domain [IPR026541]", "MRH domain [IPR044865]", "MRPL44, double-stranded RNA binding domain [IPR044444]", "MTMR6, PH-GRAM domain [IPR035998]", "MYST, zinc finger domain [IPR040706]", "Macro domain [IPR002589]", "Major facilitator superfamily domain [IPR020846]", "Major sperm protein (MSP) domain [IPR000535]", "Malectin domain [IPR021720]", "Malic enzyme, N-terminal domain [IPR012301]", "Malic enzyme, NAD-binding [IPR012302]", "Man1/Src1, C-terminal [IPR018996]", "Manganese/iron superoxide dismutase, C-terminal [IPR019832]", "Manganese/iron superoxide dismutase, N-terminal [IPR019831]", "Mannose-1-phosphate guanyltransferase, N-terminal domain [IPR045233]", "MaoC-like dehydratase domain [IPR002539]", "Marvel domain [IPR008253]", "Matrin-3, RNA recognition motif 1 [IPR034928]", "Matrin-3, RNA recognition motif 2 [IPR034930]", "Matrin/U1-C, C2H2-type zinc finger [IPR000690]", "Matrin/U1-C-like, C2H2-type zinc finger [IPR003604]", "Mcm6, C-terminal winged-helix domain [IPR041024]", "Mediator complex, subunit Med25, NR box [IPR021406]", "Mediator complex, subunit Med25, PTOV domain [IPR021394]", "Mediator complex, subunit Med25, synapsin 1 [IPR021397]", "Mediator of RNA polymerase II transcription subunit 25, von Willebrand factor type A domain [IPR021419]", "Membrane insertase YidC/Oxa1, C-terminal [IPR028055]", "Metallo-beta-lactamase [IPR001279]", "Metastasis-associated protein MTA1, R1 domain [IPR035170]", "Metaxin, glutathione S-transferase domain [IPR033468]", "Methionine--tRNA ligase, N-terminal [IPR041598]", "Methioninyl-tRNA synthetase core domain [IPR033911]", "Methionyl-tRNA synthetase, anticodon-binding domain [IPR041872]", "Methionyl/Leucyl tRNA synthetase [IPR015413]", "Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding [IPR013155]", "Methyl-CpG DNA binding [IPR001739]", "Methylglyoxal synthase-like domain [IPR011607]", "Methylmalonyl-CoA mutase, C-terminal [IPR006159]", "Methylmalonyl-CoA mutase, alpha chain, catalytic [IPR006098]", "Methylmalonyl-CoA mutase, alpha/beta chain, catalytic [IPR006099]", "Methylthiotransferase, N-terminal [IPR013848]", "Methyltransferase domain 25 [IPR041698]", "Methyltransferase domain [IPR025714]", "Methyltransferase type 11 [IPR013216]", "Methyltransferase type 12 [IPR013217]", "Mff-like domain [IPR039433]", "Mib-herc2 [IPR010606]", "Midasin AAA lid domain 5 [IPR041190]", "Midasin, AAA lid domain 7 [IPR040848]", "Midline-1, COS domain [IPR040859]", "Minichromosome loss protein Mcl1, middle region [IPR022100]", "Misato Segment II tubulin-like domain [IPR019605]", "Mitochondrial apoptosis-inducing factor, C-terminal domain [IPR029324]", "Mitochondrial cytochrome c oxidase subunit VIc/VIIs [IPR034884]", "Mitochondrial degradasome RNA helicase subunit, C-terminal domain [IPR022192]", "Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564]", "Mitochondrial ribosomal protein L46 NUDIX [IPR033650]", "Molybdenum cofactor sulfurase, C-terminal [IPR005302]", "Molybdopterin oxidoreductase [IPR006656]", "Molybdopterin oxidoreductase, 4Fe-4S domain [IPR006963]", "Mre11 nuclease, N-terminal metallophosphatase domain [IPR041796]", "Mre11, DNA-binding [IPR007281]", "Mst1 SARAH domain [IPR024205]", "Mu homology domain [IPR028565]", "Mu2, C-terminal domain [IPR043512]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal [IPR031717]", "Multiple myeloma tumor-associated protein 2-like, N-terminal [IPR019315]", "Multiprotein bridging factor 1, N-terminal [IPR013729]", "Mvd1, C-terminal [IPR041431]", "Myb domain [IPR017930]", "Myo-inositol-1-phosphate synthase, GAPDH-like [IPR013021]", "Myosin VI, cargo binding domain [IPR032412]", "Myosin head, motor domain [IPR001609]", "Myosin phosphatase-RhoA interacting protein, PH domain [IPR039597]", "Myosin tail [IPR002928]", "Myosin, N-terminal, SH3-like [IPR004009]", "Myosin-binding domain [IPR026859]", "Myotubularin-like phosphatase domain [IPR010569]", "Myristoyl-CoA:protein N-myristoyltransferase, C-terminal [IPR022677]", "Myristoyl-CoA:protein N-myristoyltransferase, N-terminal [IPR022676]", "N-acetylgalactosaminyltransferase [IPR045885]", "N-acetylneuraminic acid synthase, N-terminal [IPR013132]", "NACHT nucleoside triphosphatase [IPR007111]", "NAD(P) binding domain of glutamate dehydrogenase [IPR033922]", "NAD(P) transhydrogenase, alpha subunit, C-terminal [IPR024605]", "NAD(P)-binding domain [IPR016040]", "NAD-dependent epimerase/dehydratase [IPR001509]", "NAD/GMP synthase [IPR022310]", "NADH pyrophosphatase-like, N-terminal [IPR015375]", "NADH-quinone oxidoreductase, chain G, C-terminal [IPR015405]", "NADH-quinone oxidoreductase, subunit D [IPR001135]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain [IPR011538]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain [IPR019575]", "NADH:ubiquinone oxidoreductase, 30kDa subunit [IPR001268]", "NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding [IPR019574]", "NADH:ubiquinone oxidoreductase-like, 20kDa subunit [IPR006137]", "NADP transhydrogenase beta-like domain [IPR034300]", "NADP-dependent oxidoreductase domain [IPR023210]", "NDUFA6, LYR domain [IPR045299]", "NDUFB9, LYR domain [IPR045292]", "NECAP, PHear domain [IPR012466]", "NEDD8 ultimate buster 1, ubiquitin-like domain [IPR041207]", "NET domain [IPR027353]", "NF-kappaB-repression factor, R3H domain [IPR034071]", "NFACT protein, C-terminal [IPR021846]", "NFACT, RNA-binding domain [IPR008532]", "NGN domain [IPR005100]", "NGN domain, eukaryotic [IPR039385]", "NHL2, NHL repeat domain [IPR045302]", "NIF system FeS cluster assembly, NifU, N-terminal [IPR002871]", "NIPSNAP [IPR012577]", "NLE [IPR012972]", "NOG, C-terminal [IPR012973]", "NOG1, N-terminal helical domain [IPR041623]", "NOP5, N-terminal [IPR012974]", "NOPS [IPR012975]", "NOSIC [IPR012976]", "NP60, PWWP domain [IPR035501]", "NPL4, zinc-binding putative [IPR007716]", "NSD, Cys-His rich domain [IPR041306]", "NUC205 domain [IPR012584]", "NUDIX hydrolase [IPR020476]", "NUDIX hydrolase domain [IPR000086]", "NVL2, nucleolin binding domain [IPR031996]", "Nascent polypeptide-associated complex NAC domain [IPR002715]", "Nck1, SH2 domain [IPR035882]", "Nck1, SH3 domain 1 [IPR035562]", "Nck1, SH3 domain 2 [IPR035564]", "Nck1, SH3 domain 3 [IPR035565]", "Negative elongation factor E, RNA recognition motif [IPR034637]", "Neurobeachin-like, DUF1088 [IPR010508]", "Neurobeachin/BDCP, DUF4704 [IPR031570]", "Nibrin, second BRCT domain [IPR032429]", "Nicastrin, small lobe [IPR041084]", "Nicotinamide phosphoribosyltransferase, N-terminal domain [IPR041529]", "Nicotinate/nicotinamide phosphoribosyltransferase [IPR041525]", "Niemann-Pick C1, N-terminal [IPR032190]", "Nitric oxide synthase-interacting protein, zinc-finger [IPR031790]", "Non-canonical purine NTP phosphatase/PRRC1 [IPR026533]", "Nop domain [IPR002687]", "Nop2p [IPR011023]", "Nrap protein domain 1 [IPR035082]", "Nrap protein, domain 2 [IPR035367]", "Nrap protein, domain 3 [IPR035368]", "Nrap protein, domain 4 [IPR035369]", "Nrap protein, domain 5 [IPR035370]", "Nrap protein, domain 6 [IPR035371]", "Nuclear RNA export factor Tap, RNA-binding domain [IPR015245]", "Nuclear condensin complex subunit 3, C-terminal domain [IPR025977]", "Nuclear migration protein nudC [IPR032572]", "Nuclear pore complex protein Nup214, phenylalanine-glycine (FG) domain [IPR041553]", "Nuclear pore complex, NUP2/50/61 [IPR015007]", "Nuclear pore localisation protein NPL4, C-terminal [IPR007717]", "Nuclear pore localisation protein Npl4, ubiquitin-like domain [IPR024682]", "Nuclear protein 96 [IPR021967]", "Nuclear transport factor 2 domain [IPR002075]", "Nuclear transport factor 2, eukaryote [IPR018222]", "Nuclear-interacting partner of ALK/Rsm1-like [IPR013909]", "Nucleolar GTP-binding protein 1, Rossman-fold domain [IPR010674]", "Nucleolar GTP-binding protein 2, N-terminal domain [IPR012971]", "Nucleolar complex-associated protein 3, N-terminal [IPR011501]", "Nucleolar pre-ribosomal-associated protein 1, C-terminal domain [IPR032436]", "Nucleolar pre-ribosomal-associated protein 1, N-terminal [IPR021714]", "Nucleolar protein 7, C-terminal [IPR012579]", "Nucleolar protein 8, RNA recognition motif [IPR034138]", "Nucleolin, RNA recognition motif 1 [IPR034230]", "Nucleolin, RNA recognition motif 2 [IPR034233]", "Nucleolin, RNA recognition motif 3 [IPR034234]", "Nucleolin, RNA recognition motif 4 [IPR034235]", "Nucleophosmin, C-terminal [IPR032569]", "Nucleoplasmin core domain [IPR024057]", "Nucleoporin Nup153, N-terminal [IPR013913]", "Nucleoporin Nup188, N-terminal [IPR018864]", "Nucleoporin Nup54, alpha-helical domain [IPR025712]", "Nucleoporin, NSP1-like, C-terminal [IPR007758]", "Nucleoporin, Nup133/Nup155-like, C-terminal [IPR007187]", "Nucleoporin, Nup133/Nup155-like, N-terminal [IPR014908]", "Nucleoprotein TPR/MLP1 [IPR012929]", "Nucleoredoxin, redox inactive TRX-like domain b' [IPR041861]", "Nucleoside diphosphate kinase-like domain [IPR034907]", "Nucleoside phosphorylase domain [IPR000845]", "Nucleotide exchange factor Fes1 [IPR013918]", "Nucleotidyl transferase domain [IPR005835]", "NudC N-terminal domain [IPR025934]", "NudC domain-containing protein 2, p23 domain [IPR037902]", "NuoE domain [IPR042128]", "Nup358/RanBP2 E3 ligase domain [IPR022011]", "Nup54, C-terminal interacting domain [IPR040985]", "NusG, N-terminal [IPR006645]", "O-GlcNAc transferase, C-terminal [IPR029489]", "OB-fold nucleic acid binding domain, AA-tRNA synthetase-type [IPR004365]", "OBG-type guanine nucleotide-binding (G) domain [IPR031167]", "OCRE domain [IPR041591]", "OCRL1, PH domain [IPR037787]", "OCRL1/INPP5B, INPP5c domain [IPR037793]", "OTU domain [IPR003323]", "Origin recognition complex subunit 3, N-terminal [IPR045667]", "Origin recognition complex subunit 3, insertion domain [IPR045663]", "Origin recognition complex subunit 3, winged helix C-terminal [IPR040855]", "Orotate phosphoribosyl transferase domain [IPR004467]", "Orotidine 5'-phosphate decarboxylase domain [IPR001754]", "Ovarian carcinoma immunoreactive antigen domain [IPR009764]", "Oxidoreductase FAD/NAD(P)-binding [IPR001433]", "Oxidoreductase, N-terminal domain [IPR041694]", "Oxoglutarate/iron-dependent dioxygenase [IPR005123]", "P-type ATPase, haloacid dehalogenase domain [IPR044492]", "P-type trefoil domain [IPR000519]", "PA domain [IPR003137]", "PABP, RNA recognition motif 2 [IPR045305]", "PACSIN1/PACSIN2, SH3 domain [IPR035743]", "PACSIN2, F-BAR domain [IPR037453]", "PADR1 domain [IPR012982]", "PAP/25A-associated [IPR002058]", "PARN, R3H domain [IPR034042]", "PAS domain [IPR000014]", "PAZ domain [IPR003100]", "PB1 domain [IPR000270]", "PCNA-associated factor, histone-like domain [IPR031444]", "PDIP3, RNA recognition motif [IPR034784]", "PDZ domain [IPR001478]", "PET domain [IPR010442]", "PET testin [IPR033724]", "PH-BEACH domain [IPR023362]", "PI31 proteasome regulator, N-terminal [IPR021625]", "PI31 proteasome regulator, C-terminal [IPR013886]", "PI3K-C2-alpha, catalytic domain [IPR037705]", "PIH1, N-terminal [IPR012981]", "PIH1D1/2/3, CS-like domain [IPR041442]", "PIK-related kinase [IPR014009]", "PIK-related kinase, FAT [IPR003151]", "PIN domain [IPR002716]", "PITH domain [IPR010400]", "PLC-gamma, C-terminal SH2 domain [IPR035023]", "PLC-gamma, N-terminal SH2 domain [IPR035024]", "PLD-like domain [IPR032803]", "POLO box domain [IPR000959]", "POPLD domain [IPR012590]", "POTRA domain [IPR034746]", "PP2B, metallophosphatase domain [IPR041751]", "PP5, C-terminal metallophosphatase domain [IPR041753]", "PPIL4-like, cyclophilin domain [IPR035538]", "PPM-type phosphatase domain [IPR001932]", "PPP domain [IPR013235]", "PRKAA1, UBA-like autoinhibitory domain [IPR028797]", "PRKRA, first double-stranded RNA binding domain [IPR044465]", "PRKRA, second double-stranded RNA binding domain [IPR044466]", "PRKRA, third double-stranded RNA binding domain [IPR044467]", "PRMT5 arginine-N-methyltransferase [IPR035075]", "PRMT5, TIM barrel domain [IPR035247]", "PRMT5, oligomerisation domain [IPR035248]", "PRO8NT domain [IPR012591]", "PROCN domain [IPR012592]", "PROCT domain [IPR012984]", "PRP1 splicing factor, N-terminal [IPR010491]", "PRP8 domain IV core [IPR021983]", "PSF, NOPS domain [IPR034526]", "PSF, RNA recognition motif 1 [IPR034525]", "PSI domain [IPR016201]", "PSP, proline-rich [IPR006568]", "PSP1, RNA recognition motif 1 [IPR034522]", "PSP1, RNA recognition motif 2 [IPR034523]", "PTB/PI domain [IPR006020]", "PTBP1, RNA recognition motif 1 [IPR035000]", "PTBP1, RNA recognition motif 2-like [IPR021790]", "PTBP1, RNA recognition motif 3 [IPR035001]", "PUA domain [IPR002478]", "PUF60, RNA recognition motif 1 [IPR034209]", "PUF60, RNA recognition motif 2 [IPR034211]", "PUF60, RNA recognition motif 3 [IPR034212]", "PWI domain [IPR002483]", "PWWP domain [IPR000313]", "Paf1 complex subunit Cdc73, N-terminal domain [IPR032041]", "Palladin, C-terminal immunoglobulin-like domain [IPR033017]", "Palmitoyltransferase, DHHC domain [IPR001594]", "Patatin-like phospholipase domain [IPR002641]", "Patatin-like phospholipase domain containing protein 8-like [IPR045217]", "Pentacotripeptide-repeat region of PRORP [IPR033443]", "Pep3/Vps18/deep orange [IPR007810]", "Peptidase C12, C-terminal domain [IPR041507]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase [IPR001578]", "Peptidase C14, p20 domain [IPR001309]", "Peptidase C14, caspase non-catalytic subunit p10 [IPR002138]", "Peptidase C14A, caspase catalytic domain [IPR015917]", "Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394]", "Peptidase C19, ubiquitin-specific peptidase, DUSP domain [IPR006615]", "Peptidase C1A, papain C-terminal [IPR000668]", "Peptidase C1A, propeptide [IPR012599]", "Peptidase C2, calpain, catalytic domain [IPR001300]", "Peptidase C2, calpain, domain III [IPR022683]", "Peptidase C2, calpain, large subunit, domain III [IPR022682]", "Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal [IPR015211]", "Peptidase M1, membrane alanine aminopeptidase [IPR014782]", "Peptidase M13, C-terminal domain [IPR018497]", "Peptidase M13, N-terminal domain [IPR008753]", "Peptidase M14, carboxypeptidase A [IPR000834]", "Peptidase M16, C-terminal [IPR007863]", "Peptidase M16, N-terminal [IPR011765]", "Peptidase M16, middle/third domain [IPR032632]", "Peptidase M16C associated [IPR013578]", "Peptidase M17, leucyl aminopeptidase, C-terminal [IPR000819]", "Peptidase M17, leucyl aminopeptidase, N-terminal [IPR008283]", "Peptidase M20, dimerisation domain [IPR011650]", "Peptidase M24 [IPR000994]", "Peptidase M24, C-terminal domain [IPR032416]", "Peptidase M28 [IPR007484]", "Peptidase M3A/M3B catalytic domain [IPR001567]", "Peptidase M41 [IPR000642]", "Peptidase M41, FtsH extracellular [IPR011546]", "Peptidase M48 [IPR001915]", "Peptidase S16, Lon proteolytic domain [IPR008269]", "Peptidase S24/S26A/S26B/S26C [IPR015927]", "Peptidase S26 [IPR019533]", "Peptidase S53, activation domain [IPR015366]", "Peptidase S59, nucleoporin [IPR007230]", "Peptidase S8/S53 domain [IPR000209]", "Peptidase S8A, tripeptidyl peptidase II [IPR022229]", "Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375]", "Peptidase S9A, N-terminal domain [IPR023302]", "Peptidase family M60 domain [IPR031161]", "Peptide chain release factor class I [IPR000352]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type [IPR000297]", "Pericentriolar material 1 protein, C-terminal [IPR031446]", "Peripheral subunit-binding domain [IPR004167]", "Peroxiredoxin, C-terminal [IPR019479]", "Peroxisome membrane anchor protein Pex14p, N-terminal [IPR006785]", "PheRS DNA binding domain 2 [IPR040586]", "PheRS, DNA binding domain 1 [IPR040724]", "PheRS, DNA binding domain 3 [IPR040725]", "Phenylacetic acid degradation-related domain [IPR003736]", "Phenylalanine--tRNA ligase beta subunit, B1 domain [IPR040659]", "Phenylalanyl tRNA synthetase beta chain, core domain [IPR041616]", "Phenylalanyl-tRNA synthetase [IPR002319]", "Phosducin, thioredoxin-like domain [IPR024253]", "Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403]", "Phosphatidylinositol 3-kinase Ras-binding (PI3K RBD) domain [IPR000341]", "Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha, PX domain [IPR042133]", "Phosphatidylinositol-specific phospholipase C, X domain [IPR000909]", "Phosphoenolpyruvate carboxykinase, C-terminal P-loop domain [IPR035077]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal [IPR035078]", "Phosphofructokinase domain [IPR000023]", "Phosphoglucose isomerase, SIS domain 1 [IPR035476]", "Phosphoglucose isomerase, SIS domain 2 [IPR035482]", "Phosphoinositide 3-kinase, accessory (PIK) domain [IPR001263]", "Phospholipase C, phosphatidylinositol-specific, Y domain [IPR001711]", "Phospholipase D/Transphosphatidylase [IPR001736]", "Phospholipase/carboxylesterase/thioesterase [IPR003140]", "Phospholipid/glycerol acyltransferase [IPR002123]", "Phosphopantetheine binding ACP domain [IPR009081]", "Phosphoribosylformylglycinamidine synthase, N-terminal [IPR040707]", "Phosphoribosylformylglycinamidine synthase, linker domain [IPR041609]", "Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain [IPR020561]", "Phosphoribosylglycinamide synthetase, C-domain [IPR020560]", "Phosphoribosylglycinamide synthetase, N-terminal [IPR020562]", "Phosphoribosyltransferase domain [IPR000836]", "Phosphoribulokinase/uridine kinase [IPR006083]", "Phosphorylated adapter RNA export protein, RNA-binding domain [IPR019385]", "Phosphotyrosine protein phosphatase I [IPR023485]", "Phox homology [IPR001683]", "Pinin/SDK [IPR006787]", "Pinin/SDK/MemA protein [IPR006786]", "Pirin, C-terminal domain [IPR008778]", "Pirin, N-terminal domain [IPR003829]", "Plasma membrane calcium transporting P-type ATPase, C-terminal [IPR022141]", "Pleckstrin homology domain 9 [IPR041681]", "Pleckstrin homology domain [IPR001849]", "Pleckstrin homology domain, spectrin-type [IPR001605]", "Plectin/S10, N-terminal [IPR005326]", "Polo-like kinase 1, catalytic domain [IPR033702]", "Poly(A) polymerase, RNA-binding domain [IPR007010]", "Poly(A) polymerase, central domain [IPR007012]", "Poly(A)-specific ribonuclease, RNA-binding [IPR014789]", "Poly(ADP-ribose) polymerase, catalytic domain [IPR012317]", "Poly(ADP-ribose) polymerase, regulatory domain [IPR004102]", "Polyadenylate-binding protein/Hyperplastic disc protein [IPR002004]", "Polyamine biosynthesis domain [IPR030374]", "Polycomb group protein, RNA binding region [IPR033763]", "Polycomb protein, VEFS-Box [IPR019135]", "Polyketide synthase, C-terminal extension [IPR032821]", "Polyketide synthase, beta-ketoacyl synthase domain [IPR020841]", "Polyketide synthase, dehydratase domain [IPR020807]", "Polyketide synthase, enoylreductase domain [IPR020843]", "Polyketide synthase, ketoreductase domain [IPR013968]", "Polyketide synthase, phosphopantetheine-binding domain [IPR020806]", "Polymerase, nucleotidyl transferase domain [IPR002934]", "Polypyrimidine tract-binding protein1/2/3, RNA recognition motif 2 [IPR034798]", "Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain [IPR032319]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain [IPR015848]", "Polysaccharide biosynthesis domain [IPR021148]", "Pop1, N-terminal [IPR009723]", "Possible tRNA binding domain [IPR027992]", "Post-SET domain [IPR003616]", "Potassium channel tetramerisation-type BTB domain [IPR003131]", "Pre-PUA domain [IPR041366]", "Pre-SET domain [IPR007728]", "Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term [IPR021718]", "Pre-mRNA cleavage complex subunit Clp1, C-terminal [IPR010655]", "Pre-mRNA polyadenylation factor Fip1 domain [IPR007854]", "Pre-mRNA processing factor 4 (PRP4)-like [IPR014906]", "Pre-mRNA splicing factor component Cdc5p/Cef1, C-terminal [IPR021786]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding [IPR019581]", "Pre-mRNA-processing-splicing factor 8, U6-snRNA-binding [IPR019580]", "Pre-mRNA-splicing factor 19 [IPR013915]", "Pre-mRNA-splicing factor 3 [IPR013881]", "Pre-rRNA-processing protein Ipi1, N-terminal [IPR024679]", "Pre-rRNA-processing protein RIX1, N-terminal [IPR012583]", "Predicted HAD-superfamily phosphatase, subfamily IA/Epoxide hydrolase, N-terminal [IPR011945]", "Prenylcysteine lyase [IPR010795]", "Proliferating cell nuclear antigen, PCNA, C-terminal [IPR022649]", "Proliferating cell nuclear antigen, PCNA, N-terminal [IPR022648]", "Proline-tRNA ligase, class II, C-terminal [IPR016061]", "Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]", "Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547]", "Prolyl 4-hydroxylase, alpha subunit [IPR006620]", "Prolyl-tRNA synthetase, catalytic domain [IPR033721]", "Propionyl-coenzyme A carboxylase, BT domain [IPR041265]", "Prostaglandin E synthase 2, C-terminal [IPR034335]", "Proteasomal ATPase OB C-terminal domain [IPR032501]", "Proteasome activator Blm10, mid region [IPR032430]", "Proteasome activator PA28, C-terminal domain [IPR003186]", "Proteasome activator PA28, N-terminal domain [IPR003185]", "Proteasome activator complex subunit 4 C-terminal domain [IPR021843]", "Proteasome alpha-subunit, N-terminal domain [IPR000426]", "Proteasome beta subunit, C-terminal [IPR024689]", "Proteasome component (PCI) domain [IPR000717]", "Protein HGH1 C-terminal [IPR007206]", "Protein HGH1 N-terminal [IPR007205]", "Protein Kinase B beta, catalytic domain [IPR034677]", "Protein Kinase B, pleckstrin homology domain [IPR039026]", "Protein O-mannosyl-transferase TMTC, DUF1736 [IPR013618]", "Protein RED, C-terminal [IPR012492]", "Protein disulfide-isomerase A3, first redox inactive TRX-like domain b [IPR041868]", "Protein disulfide-isomerase A4, TRX-like domain b [IPR041866]", "Protein disulfide-isomerase A5, N-terminal TRX-like b domain [IPR041865]", "Protein kinase B alpha, catalytic domain [IPR034676]", "Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219]", "Protein kinase domain [IPR000719]", "Protein kinase, C-terminal [IPR017892]", "Protein of unknown function DUF3504 [IPR021893]", "Protein of unknown function DUF3715 [IPR022188]", "Protein phosphatase 1 binding domain [IPR029334]", "Protein polybromo-1, Bromodomain 5 [IPR037968]", "Protein quaking, putative nuclear localisation signal [IPR032367]", "Protein-tyrosine phosphatase, catalytic [IPR003595]", "Prp31 C-terminal [IPR019175]", "Pseudouridine synthase I, TruA, alpha/beta domain [IPR020097]", "Pseudouridine synthase II, N-terminal [IPR002501]", "Pseudouridine synthase, TruD, insertion domain [IPR011760]", "Pumilio homology domain [IPR033133]", "Pumilio, RNA binding domain [IPR033712]", "PurE domain [IPR000031]", "PurM-like, C-terminal domain [IPR010918]", "PurM-like, N-terminal domain [IPR016188]", "Putative 5-3 exonuclease [IPR004859]", "Putative RNA methylase domain [IPR000241]", "Putative RNA-binding protein 27, RNA recognition motif [IPR034451]", "Putative WW-binding domain and destruction box [IPR033461]", "Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain [IPR004099]", "Pyridoxamine 5'-phosphate oxidase, putative [IPR011576]", "Pyridoxamine kinase/Phosphomethylpyrimidine kinase [IPR013749]", "Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal [IPR019576]", "Pyrroline-5-carboxylate reductase, catalytic, N-terminal [IPR028939]", "Pyrroline-5-carboxylate reductase, dimerisation domain [IPR029036]", "Pyruvate carboxyltransferase [IPR000891]", "Pyruvate kinase, C-terminal [IPR015795]", "Pyruvate kinase, barrel [IPR015793]", "R3H domain [IPR001374]", "RABX5, catalytic core helical domain [IPR041545]", "RAD23A/RAD23B, UBA1 domain [IPR041811]", "RAD50, zinc hook [IPR013134]", "RAD51 interacting motif [IPR031419]", "RAP domain [IPR013584]", "RBM10, OCRE domain [IPR035618]", "RBM12, RNA recognition motif 1 [IPR034591]", "RBM12, RNA recognition motif 2 [IPR034594]", "RBM12, RNA recognition motif 3 [IPR034855]", "RBM12, RNA recognition motif 4 [IPR034856]", "RBM12, RNA recognition motif 5 [IPR034854]", "RBM12B, RNA recognition motif 2 [IPR034588]", "RBM12B, RNA recognition motif 3 [IPR034858]", "RBM14, RNA recognition motif 1 [IPR034506]", "RBM14, RNA recognition motif 2 [IPR034507]", "RBM15, RNA recognition motif 1 [IPR034470]", "RBM15, RNA recognition motif 2 [IPR034472]", "RBM15, RNA recognition motif 3 [IPR034473]", "RBM1CTR [IPR012604]", "RBM25, RNA recognition motif [IPR034268]", "RBM26, RNA recognition motif 1 [IPR034859]", "RBM26-like, RNA recognition motif 2 [IPR039511]", "RBM3/CIRBP, RNA recognition motif [IPR034278]", "RBM34, RNA recognition motif 1 [IPR034220]", "RBM34, RNA recognition motif 2 [IPR034221]", "RBM4, RNA recognition motif 1 [IPR034897]", "RBM4, RNA recognition motif 2 [IPR034898]", "RBM8, RNA recognition motif [IPR033744]", "RDD [IPR010432]", "RED-like, N-terminal [IPR012916]", "RH1 domain [IPR034743]", "RH2 domain [IPR034744]", "RII binding domain [IPR018459]", "RING-type zinc-finger, LisH dimerisation motif [IPR027370]", "RL domain [IPR041252]", "RLI, domain 1 [IPR034348]", "RNA 3'-terminal phosphate cyclase domain [IPR023797]", "RNA 3'-terminal phosphate cyclase, insert domain [IPR013791]", "RNA binding activity-knot of a chromodomain [IPR025995]", "RNA exonuclease 4, DEDDh 3'-5' exonuclease domain [IPR037431]", "RNA helicase UPF1, 1B domain [IPR040812]", "RNA helicase UPF1, Cys/His rich zinc-binding domain [IPR018999]", "RNA helicase, DEAD-box type, Q motif [IPR014014]", "RNA methyltransferase bin3, C-terminal [IPR010675]", "RNA polymerase Rpb1, domain 1 [IPR007080]", "RNA polymerase Rpb1, domain 3 [IPR007066]", "RNA polymerase Rpb1, domain 4 [IPR007083]", "RNA polymerase Rpb1, domain 5 [IPR007081]", "RNA polymerase Rpb1, domain 6 [IPR007075]", "RNA polymerase Rpb1, domain 7 [IPR007073]", "RNA polymerase Rpb2, domain 2 [IPR007642]", "RNA polymerase Rpb2, domain 3 [IPR007645]", "RNA polymerase Rpb2, domain 4 [IPR007646]", "RNA polymerase Rpb2, domain 5 [IPR007647]", "RNA polymerase Rpb2, domain 7 [IPR007641]", "RNA polymerase Rpb7-like , N-terminal [IPR005576]", "RNA polymerase, N-terminal [IPR006592]", "RNA polymerase, Rpb5, N-terminal [IPR005571]", "RNA polymerase, alpha subunit [IPR000722]", "RNA polymerase, beta subunit, protrusion [IPR007644]", "RNA polymerase, subunit H/Rpb5 C-terminal [IPR000783]", "RNA recognition motif domain [IPR000504]", "RNA recognition motif domain, eukaryote [IPR003954]", "RNA recognition motif, spliceosomal PrP8 [IPR019582]", "RNA-binding S4 domain [IPR002942]", "RNA-binding domain, S1 [IPR022967]", "RNA-binding protein 10, RNA recognition motif 2 [IPR034992]", "RNA-polymerase II-associated protein 3-like, C-terminal domain [IPR025986]", "RNA-recognition motif (RRM) Nup35-type domain [IPR007846]", "RNPS1, RNA recognition motif [IPR034201]", "RNase L inhibitor RLI-like, possible metal-binding domain [IPR007209]", "ROCK, Rho binding domain [IPR015008]", "ROK, N-terminal [IPR012987]", "RPN1, N-terminal [IPR040892]", "RPN13, DEUBAD domain [IPR032368]", "RQC domain [IPR018982]", "RUN domain [IPR004012]", "RWD domain [IPR006575]", "RZZ complex, subunit KNTC1/ROD, C-terminal [IPR019527]", "Rab geranylgeranyltransferase, alpha subunit, insert-domain [IPR009087]", "Rab-GTPase-TBC domain [IPR000195]", "Rab-binding domain FIP-RBD [IPR019018]", "Rab3-GAP regulatory subunit, N-terminal [IPR032839]", "Rab3GAP catalytic subunit, C-terminal [IPR045698]", "Rab3GAP catalytic subunit, conserved domain [IPR026147]", "Rab3GAP regulatory subunit, C-terminal [IPR029257]", "Rad21/Rec8-like protein, C-terminal, eukaryotic [IPR006909]", "Rad21/Rec8-like protein, N-terminal [IPR006910]", "Rad50, ATP-binding cassette domain [IPR045171]", "Rad50/SbcC-type AAA domain [IPR038729]", "Radical SAM [IPR007197]", "Radical SAM, C-terminal extension [IPR032432]", "Raly, RNA recognition motif [IPR034502]", "Ran binding domain [IPR000156]", "Ran binding protein 9/10, SPRY domain [IPR035782]", "Ran-GTPase activating protein 1, C-terminal [IPR009109]", "Ran-specific GTPase-activating protein 1, Ran-binding domain [IPR045256]", "Rap/Ran-GAP domain [IPR000331]", "Rap1 Myb domain [IPR015010]", "Ras GTPase-activating domain [IPR001936]", "Ras GTPase-activating protein 1, C-terminal SH2 domain [IPR035842]", "Ras GTPase-activating protein 1, N-terminal SH2 domain [IPR035841]", "Ras guanine-nucleotide exchange factors catalytic domain [IPR001895]", "Ras-associating (RA) domain [IPR000159]", "Ras-like guanine nucleotide exchange factor, N-terminal [IPR000651]", "RasGAP protein, C-terminal [IPR000593]", "RasGAP, SH3 domain [IPR035652]", "RecF/RecN/SMC, N-terminal [IPR003395]", "Receptor L-domain [IPR000494]", "Redoxin [IPR013740]", "Regulator of G protein signalling-like domain [IPR015212]", "Replication factor A, C-terminal [IPR013955]", "Replication factor C, C-terminal [IPR013748]", "Replication factor-A protein 1, N-terminal [IPR007199]", "Replication protein A, C-terminal [IPR014892]", "Replication protein A, OB domain [IPR031657]", "Replication termination factor 2, RING-finger [IPR027799]", "Reticulon [IPR003388]", "Rho GTPase-activating protein domain [IPR000198]", "Rho GTPase-activating protein, FF domain [IPR032835]", "Rho GTPase-activating protein, pG1 and pG2 domain [IPR045786]", "Rho GTPase-activating protein, pG1 domain [IPR039007]", "Rho GTPase-activating protein, pG2 domain [IPR039006]", "Rho GTPase-binding/formin homology 3 (GBD/FH3) domain [IPR014768]", "Rho guanine nucleotide exchange factor 7, SH3 domain [IPR035789]", "Rho-associated protein kinase 2, HR1 domain [IPR037311]", "Rhodanese-like domain [IPR001763]", "Ribonuclease H1, N-terminal [IPR011320]", "Ribonuclease H2 subunit B, wHTH domain [IPR019024]", "Ribonuclease HII/HIII domain [IPR024567]", "Ribonuclease II/R [IPR001900]", "Ribonuclease III domain [IPR000999]", "Ribonucleoprotein PTB-binding 1, RNA recognition motif 1 [IPR034633]", "Ribonucleotide reductase large subunit, C-terminal [IPR000788]", "Ribonucleotide reductase large subunit, N-terminal [IPR013509]", "Ribonucleotide reductase, class I , alpha subunit [IPR013346]", "Ribose-phosphate pyrophosphokinase, N-terminal domain [IPR029099]", "Ribosomal L28e/Mak16 [IPR029004]", "Ribosomal Protein L6, KOW domain [IPR041997]", "Ribosomal Proteins L2, RNA binding domain [IPR022666]", "Ribosomal RNA methyltransferase FtsJ domain [IPR002877]", "Ribosomal RNA methyltransferase Spb1, domain of unknown function DUF3381 [IPR024576]", "Ribosomal RNA methyltransferase, Spb1, C-terminal [IPR012920]", "Ribosomal RNA small subunit methyltransferase F, N-terminal [IPR031341]", "Ribosomal RNA-processing protein 14/surfeit locus protein 6, C-terminal domain [IPR029190]", "Ribosomal S6 kinase, N-terminal catalytic domain [IPR041906]", "Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A [IPR023573]", "Ribosomal protein L10e/L16 [IPR016180]", "Ribosomal protein L11, C-terminal [IPR020783]", "Ribosomal protein L11, N-terminal [IPR020784]", "Ribosomal protein L14, KOW motif [IPR041985]", "Ribosomal protein L14e domain [IPR002784]", "Ribosomal protein L18e/L15P [IPR021131]", "Ribosomal protein L19, eukaryotic [IPR033935]", "Ribosomal protein L19/L19e [IPR000196]", "Ribosomal protein L2, C-terminal [IPR022669]", "Ribosomal protein L23/L25, N-terminal [IPR005633]", "Ribosomal protein L26/L24, KOW domain [IPR041988]", "Ribosomal protein L30, N-terminal [IPR012988]", "Ribosomal protein L30, ferredoxin-like fold domain [IPR016082]", "Ribosomal protein L46, N-terminal [IPR021757]", "Ribosomal protein L5 eukaryotic, C-terminal [IPR025607]", "Ribosomal protein L5, C-terminal [IPR031309]", "Ribosomal protein L5, N-terminal [IPR031310]", "Ribosomal protein L6, N-terminal [IPR005568]", "Ribosomal protein L6, alpha-beta domain [IPR020040]", "Ribosomal protein L7, eukaryotic/archaeal [IPR035808]", "Ribosomal protein L7/L12, C-terminal [IPR013823]", "Ribosomal protein L7/L12, oligomerisation [IPR008932]", "Ribosomal protein L7Ae/L30e/S12e/Gadd45 [IPR004038]", "Ribosomal protein L9, N-terminal [IPR020070]", "Ribosomal protein S10 domain [IPR027486]", "Ribosomal protein S13/S15, N-terminal [IPR012606]", "Ribosomal protein S23/S25, mitochondrial [IPR023611]", "Ribosomal protein S24/S35, mitochondrial, conserved domain [IPR019349]", "Ribosomal protein S3, C-terminal [IPR001351]", "Ribosomal protein S4, KOW domain [IPR041982]", "Ribosomal protein S4/S9, N-terminal [IPR001912]", "Ribosomal protein S4e, N-terminal [IPR013843]", "Ribosomal protein S4e, central region [IPR013845]", "Ribosomal protein S5, C-terminal [IPR005324]", "Ribosomal protein S5, N-terminal [IPR013810]", "Ribosomal protein S6 kinase alpha-3, C-terminal catalytic domain [IPR041905]", "Ribosomal protein S7 domain [IPR023798]", "Ribosomal protein/NADH dehydrogenase domain [IPR007741]", "Ribosome biogenesis protein BMS1/TSR1, C-terminal [IPR007034]", "Ribosome biogenesis protein Bms1, N-terminal [IPR037875]", "Ribosome maturation protein Sdo1/SBDS, C-terminal [IPR018978]", "Ribosome maturation protein Sdo1/SBDS, N-terminal [IPR019783]", "Ribosome receptor lysine/proline rich [IPR007794]", "Ribosome recycling factor domain [IPR023584]", "Ricin B, lectin domain [IPR000772]", "Rieske iron-sulphur protein, C-terminal [IPR005805]", "RmlD-like substrate binding domain [IPR029903]", "Rnh202, triple barrel domain [IPR041195]", "Roadblock/LAMTOR2 domain [IPR004942]", "Rpa43, N-terminal ribonucleoprotein (RNP) domain [IPR041901]", "Rpn11/EIF3F, C-terminal [IPR024969]", "Rpn13/ADRM1, Pru domain [IPR044868]", "RrmJ-type ribose 2-O-methyltransferase domain [IPR025816]", "Rrp40, S1 domain [IPR037319]", "Rrp44-like cold shock domain [IPR033771]", "RuvB-like, AAA-lid domain [IPR041048]", "S-adenosyl-L-homocysteine hydrolase, NAD binding domain [IPR015878]", "S-adenosylmethionine synthetase, C-terminal [IPR022630]", "S-adenosylmethionine synthetase, N-terminal [IPR022628]", "S-adenosylmethionine synthetase, central domain [IPR022629]", "S1 domain [IPR003029]", "S1-like RNA binding domain [IPR025223]", "S100/CaBP-9k-type, calcium binding, subdomain [IPR013787]", "SAB domain [IPR007477]", "SAC domain [IPR002013]", "SAC3/GANP/THP3, conserved domain [IPR005062]", "SAF domain [IPR013974]", "SAICAR synthetase/ADE2, N-terminal [IPR028923]", "SAM-dependent methyltransferase RsmB/NOP2-type [IPR001678]", "SANT domain [IPR017884]", "SANT/Myb domain [IPR001005]", "SAP domain [IPR003034]", "SARAH domain [IPR011524]", "SART3, RNA recognition motif 1 [IPR034217]", "SART3, RNA recognition motif 2 [IPR034218]", "SCP2 sterol-binding domain [IPR003033]", "SEC23-interacting protein, SAM domain [IPR037603]", "SEP domain [IPR012989]", "SERRATE/Ars2 , C-terminal [IPR007042]", "SERRATE/Ars2, N-terminal [IPR021933]", "SET domain [IPR001214]", "SETD7, SET domain [IPR044436]", "SF3A2 domain [IPR031781]", "SF3A3 domain [IPR031774]", "SF3B4, RNA recognition motif 1 [IPR034158]", "SF3B4, RNA recognition motif 2 [IPR034159]", "SF3B6, RNA recognition motif [IPR034150]", "SGNH hydrolase-type esterase domain [IPR013830]", "SGS domain [IPR007699]", "SGTA, homodimerisation domain [IPR032374]", "SH2 domain [IPR000980]", "SH3 domain [IPR001452]", "SHARP, RNA recognition motif 1 [IPR034172]", "SHARP, RNA recognition motif 2 [IPR034173]", "SHARP, RNA recognition motif 3 [IPR034174]", "SHARP, RNA recognition motif 4 [IPR034175]", "SIS domain [IPR001347]", "SKI-interacting protein SKIP, SNW domain [IPR004015]", "SKP1 component, POZ domain [IPR016073]", "SKP1 component, dimerisation [IPR016072]", "SLC12A transporter, C-terminal [IPR018491]", "SLED domain [IPR021987]", "SLIDE domain [IPR015195]", "SLIRP, RNA recognition motif [IPR034152]", "SMARCA1, N-terminal [IPR044755]", "SMARCC, C-terminal [IPR032451]", "SMARCC, N-terminal [IPR032450]", "SMARCC, SWIRM-associated domain [IPR032448]", "SMCs flexible hinge [IPR010935]", "SMYD3, SET domain [IPR044420]", "SMYD5, SET domain [IPR044422]", "SNAP-25 domain [IPR000928]", "SNARE-complex protein Syntaxin-18, N-terminal [IPR019529]", "SNF2, N-terminal [IPR000330]", "SNX2, PX domain [IPR037918]", "SNX27, PX domain [IPR037833]", "SNX27, RA domain [IPR037835]", "SNX27, atypical FERM-like domain [IPR037827]", "SNX5, PX domain [IPR042135]", "SNX6, PX domain [IPR042136]", "SPF45, RNA recognition motif [IPR034653]", "SPRY domain [IPR003877]", "SPRY-associated [IPR006574]", "SR140, RNA recognition motif [IPR035009]", "SRA-YDG [IPR003105]", "SRCR domain [IPR001190]", "SRCR-like domain [IPR017448]", "SREK1, RNA recognition motif 2 [IPR034192]", "SRP9 domain [IPR039432]", "SRSF1, RNA recognition motif 1 [IPR034520]", "SRSF6, RNA recognition motif 1 [IPR034511]", "SRSF7, RNA recognition motif [IPR034651]", "SRSF9, RNA recognition motif 1 [IPR034503]", "SRSF9, RNA recognition motif 2 [IPR034995]", "SSRP1 domain [IPR024954]", "STAG [IPR013721]", "STAM1, SH3 domain [IPR035657]", "STAMBP/STALP-like, MPN domain [IPR044098]", "STAR protein, homodimerisation region [IPR032377]", "STARD11, START domain [IPR041952]", "STARD7, START domain [IPR041949]", "START domain [IPR002913]", "STAT transcription factor, DNA-binding [IPR013801]", "STAT transcription factor, all-alpha domain [IPR013800]", "STAT transcription factor, protein interaction [IPR013799]", "STAT1, SH2 domain [IPR035859]", "STAT3, SH2 domain [IPR035855]", "STI1 domain [IPR041243]", "STRBP, first double-stranded RNA binding domain [IPR044472]", "SUI1 domain [IPR001950]", "SUMO-activating enzyme subunit 2, C-terminal domain [IPR032426]", "SUN coiled coil domain 2 [IPR040994]", "SUN domain [IPR012919]", "SUN domain-containing protein 1, N-terminal [IPR032680]", "SUZ-C domain [IPR024642]", "SWAP/Surp [IPR000061]", "SWI/SNF-like complex subunit BAF250, C-terminal [IPR033388]", "SWIB/MDM2 domain [IPR003121]", "SWIRM domain [IPR007526]", "Saccharopine dehydrogenase, NADP binding domain [IPR005097]", "Saccharopine dehydrogenase-like, C-terminal [IPR032095]", "Sam68, tyrosine-rich domain [IPR032335]", "Saposin A-type domain [IPR003119]", "Saposin B type domain [IPR008139]", "Saposin B type, region 2 [IPR008138]", "Saposin-like type B, region 1 [IPR007856]", "Schlafen group 3-like, DNA/RNA helicase domain [IPR018647]", "Schlafen, AlbA_2 domain [IPR007421]", "Sde2, N-terminal ubiquitin domain [IPR024974]", "Sec16, central conserved domain [IPR024340]", "Sec23, C-terminal [IPR037550]", "Sec23/Sec24 beta-sandwich [IPR012990]", "Sec23/Sec24, helical domain [IPR006900]", "Sec23/Sec24, trunk domain [IPR006896]", "Sec24-like, trunk domain [IPR041742]", "Sec63 domain [IPR004179]", "Sec7 domain [IPR000904]", "Sec8 exocyst complex component specific domain [IPR007191]", "Second polo-box domain [IPR033695]", "Sedolisin domain [IPR030400]", "Senescence/spartin-associated, C-terminal [IPR009686]", "Sentrin-specific protease 3/5, conserved domain [IPR045577]", "Septin-type guanine nucleotide-binding (G) domain [IPR030379]", "Serine aminopeptidase, S33 [IPR022742]", "Serine hydroxymethyltransferase-like domain [IPR039429]", "Serine-tRNA ligase catalytic core domain [IPR033729]", "Serine-tRNA synthetase, type1, N-terminal [IPR015866]", "Serine-threonine protein phosphatase, N-terminal [IPR031675]", "Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245]", "Serine/arginine-rich splicing factor SRSF4-like, RNA recognition motif 1 [IPR035585]", "Serine/threonine-protein PRP4, catalytic domain [IPR044092]", "Serine/threonine-protein kinase N, C2 domain [IPR037784]", "Serine/threonine-protein kinase N, first HR1 domain [IPR037313]", "Serine/threonine-protein kinase Nek9, catalytic domain [IPR042767]", "Serine/threonine-protein kinase OSR1/WNK, CCT domain [IPR024678]", "Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase [IPR006186]", "Serpin H1, serpin domain [IPR033830]", "Serpin domain [IPR023796]", "Siah interacting protein, N-terminal [IPR015120]", "Signal recognition particle SRP54, helical bundle [IPR013822]", "Signal recognition particle receptor, alpha subunit, N-terminal [IPR007222]", "Signal recognition particle subunit SRP68, RNA-binding domain [IPR034652]", "Signal recognition particle, SRP54 subunit, GTPase domain [IPR000897]", "Signal recognition particle, SRP54 subunit, M-domain [IPR004125]", "Signal recognition particle, SRP72 subunit, RNA-binding [IPR013699]", "Signal transducer and activation of transcription 1, TAZ2 binding domain, C-terminal [IPR022752]", "Sin3, C-terminal [IPR031693]", "Sirtuin family, catalytic core domain [IPR026590]", "Ski2, N-terminal domain [IPR040801]", "Small G protein signalling modulator 1/2, Rab-binding domain [IPR021935]", "Small GTP-binding protein domain [IPR005225]", "Small acidic protein-like domain [IPR028124]", "Small nuclear ribonucleoprotein D1 [IPR034102]", "Small-subunit processome, Utp12 [IPR007148]", "Small-subunit processome, Utp13 [IPR013934]", "Small-subunit processome, Utp21 [IPR007319]", "Smc1, ATP-binding cassette domain [IPR028468]", "Smc2, ATP-binding cassette domain [IPR027120]", "Snf2, ATP coupling domain [IPR029295]", "Snu114, GTP-binding domain [IPR044121]", "Sof1-like protein [IPR007287]", "Solute carrier family 3 member 2, N-terminal domain [IPR031984]", "Sorting Nexin 1, PX domain [IPR034901]", "Sorting nexin Vps5-like, C-terminal [IPR015404]", "Sorting nexin, N-terminal [IPR005329]", "Spen paralogue and orthologue SPOC, C-terminal [IPR012921]", "Spen paralogue/orthologue C-terminal, metazoa [IPR010912]", "Spermidine synthase, tetramerisation domain [IPR035246]", "Spermine synthase, N-terminal [IPR040900]", "Splicing factor 1, helix-hairpin domain [IPR032570]", "Splicing factor 3A subunit 1, conserved domain [IPR022030]", "Splicing factor 3A subunit 1, ubiquitin domain [IPR035563]", "Splicing factor 3B subunit 1 [IPR015016]", "Splicing factor ELAV/Hu, RNA recognition motif 1 [IPR034775]", "Splicing factor RBM39, linker [IPR029123]", "Splicing factor SF3a60 /Prp9 subunit, C-terminal [IPR024598]", "Splicing factor SF3a60 binding domain [IPR021966]", "Spp2/MOS2, G-patch domain [IPR026822]", "Spt5 C-terminal domain [IPR024945]", "Spt5 transcription elongation factor, N-terminal [IPR022581]", "Spt5, KOW domain repeat 1 [IPR041973]", "Spt5, KOW domain repeat 2 [IPR041975]", "Spt5, KOW domain repeat 3 [IPR041976]", "Spt5, KOW domain repeat 4 [IPR041977]", "Spt5, KOW domain repeat 5 [IPR041978]", "Spt5, KOW domain repeat 6 [IPR041980]", "Spt6 acidic, N-terminal domain [IPR028083]", "Spt6, SH2 domain [IPR035420]", "Spt6, SH2 domain, C terminus [IPR035018]", "Spt6, SH2 domain, N terminus [IPR035019]", "Squalene cyclase, C-terminal [IPR032696]", "Squalene cyclase, N-terminal [IPR032697]", "Squalene epoxidase [IPR013698]", "Srp40, C-terminal [IPR007718]", "StAR-related lipid transfer protein 3, C-terminal [IPR029867]", "Staphylococcal nuclease (SNase-like), OB-fold [IPR016071]", "Staufen 1, third double-stranded RNA binding domain [IPR044475]", "Staufen, C-terminal [IPR032478]", "Steadiness box (SB) domain [IPR017916]", "Sterile alpha motif domain [IPR001660]", "Sterol-sensing domain [IPR000731]", "Striatin, N-terminal [IPR013258]", "Strictosidine synthase, conserved region [IPR018119]", "Stromal interaction molecule 2, SAM domain [IPR037610]", "Stromal interaction molecule, Orai1-activating region [IPR032393]", "Stromalin conservative domain [IPR020839]", "Structural maintenance of chromosomes 3, ABC domain, eukaryotic [IPR041741]", "Structural maintenance of chromosomes 4, ABC domain, eukaryotic [IPR041738]", "Succinate dehydogenase/fumarate reductase N-terminal [IPR025192]", "Sulfatase, N-terminal [IPR000917]", "Sulfhydryl oxidase, Trx-like domain [IPR041269]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain [IPR040986]", "Sulfotransferase domain [IPR000863]", "Sulphate adenylyltransferase [IPR002650]", "Sulphate adenylyltransferase catalytic domain [IPR024951]", "Suppressor of forked [IPR008847]", "Suppressor of white apricot, N-terminal domain [IPR019147]", "Survival motor neuron [IPR010304]", "Suv3, C-terminal domain 1 [IPR041082]", "Suv3, DEXQ-box helicase domain [IPR044774]", "Suv3, N-terminal [IPR041453]", "Symplekin C-terminal [IPR022075]", "Symplekin/Pta1, N-terminal [IPR032460]", "Synaptic functional regulator FMRP, KH0 domain [IPR040472]", "Synaptotagmin, SMP domain [IPR039010]", "Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468]", "Synaptotagmin-like, mitochondrial and lipid-binding domain [IPR040885]", "Syntaxin 6, N-terminal [IPR015260]", "Syntaxin, N-terminal domain [IPR006011]", "Syntaxin-5, N-terminal, Sly1p-binding domain [IPR021538]", "Syntaxin-8, SNARE domain [IPR041875]", "TAP C-terminal (TAP-C) domain [IPR005637]", "TAR DNA-binding protein 43, N-terminal [IPR041105]", "TATA box binding protein associated factor (TAF) [IPR004823]", "TATA-binding protein interacting (TIP20) [IPR013932]", "TBCE, ubiquitin-like (Ubl) domain [IPR044079]", "TCB1D9/TCB1D9B, PH-GRAM domain 1 [IPR036014]", "TCB1D9/TCB1D9B, PH-GRAM domain 2 [IPR036017]", "TFG box [IPR025768]", "TFG, PB1 domain [IPR034857]", "TFIIEalpha/SarR/Rpc3 HTH domain [IPR024550]", "TGS [IPR004095]", "THIF-type NAD/FAD binding fold [IPR000594]", "THUMP domain [IPR004114]", "TIA-1, RNA recognition motif 2 [IPR034830]", "TIA-1, RNA recognition motif 3 [IPR034832]", "TIAR, RNA recognition motif 1 [IPR034492]", "TIAR, RNA recognition motif 2 [IPR034494]", "TIAR, RNA recognition motif 3 [IPR034496]", "TIF1-beta, RING finger, HC subclass [IPR042713]", "TIP49, P-loop domain [IPR010339]", "TOG domain [IPR034085]", "TOPK, catalytic domain [IPR041989]", "TOPRIM domain [IPR006171]", "TPX2 central domain [IPR027330]", "TPX2, C-terminal [IPR027329]", "TRAM domain [IPR002792]", "TRAM/LAG1/CLN8 homology domain [IPR006634]", "TRAM1-like protein [IPR013599]", "TRASH domain [IPR011017]", "TRF2-interacting telomeric protein/Rap1, C-terminal [IPR021661]", "TRIAD supradomain [IPR044066]", "TRIM21, PRY/SPRY domain [IPR035831]", "TRIM25, PRY/SPRY domain [IPR042753]", "TRIM27, PRY/SPRY domain [IPR035791]", "TRMT2A, RNA recognition motif [IPR034262]", "TROVE domain [IPR008858]", "TSG101 and ALIX binding domain of CEP55 [IPR022008]", "TUTase nucleotidyltransferase domain [IPR045100]", "Talin, N-terminal F0 domain [IPR032425]", "Talin, central [IPR015224]", "Talin-1/2, rod-segment [IPR037438]", "Target SNARE coiled-coil homology domain [IPR000727]", "TatSF1-like, RNA recognition motif 1 [IPR034392]", "Telomere length regulation protein, conserved domain [IPR019337]", "Telomere-associated protein Rif1, N-terminal [IPR022031]", "Tensin phosphatase, C2 domain [IPR014020]", "Tensin-type phosphatase domain [IPR029023]", "Testin, LIM domain 1 [IPR034958]", "Testin, LIM domain 2 [IPR034959]", "Testin, LIM domain 3 [IPR034960]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain [IPR020631]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain [IPR020630]", "Tetratricopeptide repeat-like domain [IPR018704]", "Tetratricopeptide, SHNi-TPR domain [IPR019544]", "Tex protein, YqgF-like domain [IPR032639]", "Tex, S1 domain [IPR044146]", "Tex-like protein, N-terminal [IPR018974]", "Tfc3, extended winged-helix domain [IPR035625]", "Thiamine pyrophosphate enzyme, C-terminal TPP-binding [IPR011766]", "Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain [IPR012001]", "Thiamine pyrophosphate enzyme, central domain [IPR012000]", "Thioesterase [IPR001031]", "Thioesterase domain [IPR006683]", "Thiolase, C-terminal [IPR020617]", "Thiolase, N-terminal [IPR020616]", "Thioredoxin domain [IPR013766]", "Thioredoxin domain-containing protein 17-like domain [IPR010357]", "Thioredoxin-like fold [IPR012336]", "Thioredoxin-related transmembrane protein 2, thioredoxin domain [IPR037463]", "Threonine-tRNA ligase catalytic core domain [IPR033728]", "Threonyl/alanyl tRNA synthetase, SAD [IPR012947]", "Thymidylate kinase-like domain [IPR039430]", "Thymidylate synthase/dCMP hydroxymethylase domain [IPR023451]", "Tim10-like [IPR004217]", "Tim44-like domain [IPR007379]", "Timeless, C-terminal [IPR007725]", "Timeless, N-terminal [IPR006906]", "TopBP1, first BRCT domain [IPR044737]", "Topoisomerase I C-terminal domain [IPR025834]", "Trafficking protein particle complex subunit 11 [IPR021773]", "Trafficking protein particle complex subunit 11, C-terminal [IPR025876]", "Trans-isoprenyl diphosphate synthases, head-to-head [IPR033904]", "Transcription elongation factor S-II, central domain [IPR003618]", "Transcription elongation factor Spt6, YqgF domain [IPR028231]", "Transcription elongation factor Spt6, helix-hairpin-helix motif [IPR032706]", "Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type [IPR003617]", "Transcription factor CBF/NF-Y/archaeal histone domain [IPR003958]", "Transcription factor IIIC subunit 5, HTH domain [IPR019136]", "Transcription factor IIIC subunit Tfc1/Sfc1, triple barrel domain [IPR041499]", "Transcription factor IIS, N-terminal [IPR017923]", "Transcription factor TFE/TFIIEalpha HTH domain [IPR017919]", "Transcription factor TFIIE alpha subunit, C-terminal [IPR021600]", "Transcription initiation factor IIE subunit alpha, N-terminal [IPR002853]", "Transcription termination and cleavage factor, C-terminal domain [IPR026896]", "Transcriptional coactivator p15 (PC4), C-terminal [IPR003173]", "Transcriptional repressor p66, coiled-coil MBD2-interaction domain [IPR032346]", "Transferrin receptor protein 1/2, PA domain [IPR037324]", "Transferrin receptor-like, dimerisation domain [IPR007365]", "Transforming acidic coiled-coil-containing protein, C-terminal [IPR007707]", "Transketolase, C-terminal domain [IPR033248]", "Transketolase, N-terminal [IPR005474]", "Transketolase-like, pyrimidine-binding domain [IPR005475]", "Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain [IPR014038]", "Translation elongation factor EFG/EF2, domain IV [IPR005517]", "Translation elongation factor EFTs/EF1B, dimerisation [IPR014039]", "Translation elongation factor EFTu-like, domain 2 [IPR004161]", "Translation elongation factor EFTu/EF1A, C-terminal [IPR004160]", "Translation elongation factor, IF5A C-terminal [IPR020189]", "Translation initiation factor IF- 2, domain 3 [IPR023115]", "Translation initiation factor IF-2, domain II [IPR044145]", "Translation initiation factor IF2/IF5 domain [IPR002735]", "Translation initiation factor eIF-2B subunit epsilon, N-terminal [IPR035543]", "Translation initiation factor eIF-2B subunit epsilon, W2 domain [IPR044123]", "Translation initiation factor, beta propellor-like domain [IPR013979]", "Translational (tr)-type GTP-binding domain [IPR000795]", "Translationally controlled tumour protein (TCTP) domain [IPR034737]", "Translocon Sec61/SecY, plug domain [IPR019561]", "Treacle protein domain [IPR003993]", "Tripeptidyl-peptidase II domain [IPR034051]", "TryX and NRX, thioredoxin domain [IPR045870]", "Tuberin, N-terminal [IPR024584]", "Tuberin-type domain [IPR018515]", "Tubulin binding cofactor C-like domain [IPR012945]", "Tubulin-folding cofactor B, N-terminal ubiquitin-like domain [IPR045172]", "Tubulin-specific chaperone D, C-terminal [IPR022577]", "Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]", "Tubulin/FtsZ, GTPase domain [IPR003008]", "Tudor domain [IPR002999]", "Tuftelin interacting protein, N-terminal domain [IPR022159]", "Tumour suppressor p53-binding protein-1 Tudor domain [IPR015125]", "Tyrosine-protein kinase BAZ1B, bromodomain [IPR037375]", "Tyrosine-protein kinase, catalytic domain [IPR020635]", "Tyrosine-specific protein phosphatase, PTPase domain [IPR000242]", "Tyrosine-specific protein phosphatases domain [IPR000387]", "U-box domain [IPR003613]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 1 [IPR034407]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 2 [IPR034409]", "U1 small nuclear ribonucleoprotein of 70kDa N-terminal [IPR022023]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 2 [IPR034562]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 1 [IPR034564]", "U2A'/phosphoprotein 32 family A, C-terminal [IPR003603]", "U3 small nucleolar RNA-associated protein 10, N-terminal [IPR022125]", "U3 small nucleolar RNA-associated protein 15, C-terminal [IPR018983]", "UAS [IPR006577]", "UBX domain [IPR001012]", "UBXN1, UBA domain [IPR041923]", "UDP-N-acetylglucosamine 2-epimerase domain [IPR003331]", "UDP-glucose/GDP-mannose dehydrogenase, C-terminal [IPR014027]", "UDP-glucose/GDP-mannose dehydrogenase, N-terminal [IPR001732]", "UDP-glucose/GDP-mannose dehydrogenase, dimerisation [IPR014026]", "UDP-glucose:glycoprotein glucosyltransferase, thioredoxin-like domain 4 [IPR040525]", "UGGT, thioredoxin-like domain 1 [IPR040693]", "UGGT, thioredoxin-like domain 2 [IPR040694]", "UGGT, thioredoxin-like domain 3 [IPR040692]", "UHRF1, tandem tudor domain [IPR021991]", "UNC-45/Cro1/She4, central domain [IPR024660]", "UPF0113, PUA domain [IPR005155]", "UPF0113, pre-PUA domain [IPR040598]", "UPF3 domain [IPR005120]", "UPF3B, RNA recognition motif-like domain [IPR034979]", "USP8 dimerisation domain [IPR015063]", "UVR domain [IPR001943]", "Ubiquinol-cytochrome c reductase 8kDa, N-terminal [IPR015248]", "Ubiquinol-cytochrome c reductase, iron-sulphur subunit [IPR006317]", "Ubiquitin E2 variant, N-terminal [IPR008883]", "Ubiquitin carboxyl-terminal hydrolase 47, C-terminal [IPR045578]", "Ubiquitin carboxyl-terminal hydrolase 5, UBA1 domain [IPR041812]", "Ubiquitin carboxyl-terminal hydrolase 7, ICP0-binding domain [IPR024729]", "Ubiquitin carboxyl-terminal hydrolase, C-terminal [IPR029346]", "Ubiquitin conjugation factor E4, core [IPR019474]", "Ubiquitin specific protease domain [IPR028889]", "Ubiquitin system component CUE [IPR003892]", "Ubiquitin-activating enzyme E1, C-terminal [IPR018965]", "Ubiquitin-activating enzyme E1, FCCH domain [IPR032418]", "Ubiquitin-activating enzyme E1, four-helix bundle [IPR032420]", "Ubiquitin-activating enzyme, SCCH domain [IPR019572]", "Ubiquitin-associated domain [IPR015940]", "Ubiquitin-conjugating enzyme E2 [IPR000608]", "Ubiquitin-like domain [IPR000626]", "Ubiquitin-like domain, USP-type [IPR028135]", "Ubiquitin-specific peptidase 48 [IPR033841]", "Ubiquitin-specific-processing protease 48, Ubl domain [IPR044743]", "Ubiquitin/SUMO-activating enzyme ubiquitin-like domain [IPR028077]", "Ubiquitinyl hydrolase, variant UBP zinc finger [IPR041432]", "Ubiquitinyl hydrolase-L5 [IPR033837]", "Ulp1 protease family, C-terminal catalytic domain [IPR003653]", "Uncharacterised domain CHP00451 [IPR004521]", "Uncharacterised domain NUC173 [IPR012978]", "Uncharacterised domain NUC202 [IPR012980]", "Up-frameshift suppressor 2, C-terminal [IPR007193]", "Uracil-DNA glycosylase-like [IPR005122]", "Uroporphyrinogen decarboxylase (URO-D) [IPR000257]", "Uso1/p115-like vesicle tethering protein, C-terminal [IPR006955]", "VHS domain [IPR002014]", "VIP36, lectin domain [IPR035664]", "VPS13, repeated coiled region [IPR031642]", "VPS9 domain [IPR003123]", "Vacuolar protein 14, C-terminal Fig4-binding domain [IPR021841]", "Vacuolar protein sorting-associated protein 13, C-terminal [IPR031645]", "Vacuolar protein sorting-associated protein 13, SHR-binding domain [IPR009543]", "Vacuolar protein sorting-associated protein 13, second N-terminal domain [IPR031646]", "Vacuolar protein sorting-associated protein 13-like, N-terminal domain [IPR026854]", "Vacuolar protein sorting-associated protein 4, MIT domain [IPR045253]", "Valyl tRNA synthetase, anticodon-binding domain [IPR033705]", "Vertebrate SNX3, PX domain [IPR042137]", "Vertebrate ubiquitin-conjugating enzyme E2 K, UBA domain [IPR042599]", "Vesicle tethering protein Uso1/P115-like , head domain [IPR006953]", "Vicinal oxygen chelate (VOC) domain [IPR037523]", "Vinculin-binding site-containing domain [IPR015009]", "Vps4 oligomerisation, C-terminal [IPR015415]", "Vps53-like, N-terminal [IPR007234]", "W2 domain [IPR003307]", "WAPL domain [IPR012502]", "WD repeat-containing protein 18, C-terminal domain [IPR026987]", "WGR domain [IPR008893]", "WH2 domain [IPR003124]", "WHEP-TRS domain [IPR000738]", "WHIM1 domain [IPR028942]", "WHIM2 domain [IPR028941]", "WSTF/Acf1/Cbp146 [IPR013136]", "WW domain [IPR001202]", "WWE domain [IPR004170]", "Wings apart-like protein, C-terminal [IPR022771]", "Wolframin, EF-hand domain [IPR045460]", "Wolframin, OB-fold domain [IPR045461]", "Wolframin, cysteine-rich domain [IPR045400]", "XPC-binding domain [IPR015360]", "XPG, N-terminal [IPR006085]", "XPG-I domain [IPR006086]", "XRCC1, first (central) BRCT domain [IPR045080]", "XRN2-binding (XTBD) domain [IPR021859]", "Xrn1, helical domain [IPR041412]", "YKT6, SNARE motif [IPR045848]", "YTH domain [IPR007275]", "YchF, C-terminal domain [IPR013029]", "YchF, N-terminal [IPR041706]", "YjeF N-terminal domain [IPR004443]", "YqgF/RNase H-like domain [IPR006641]", "YrdC-like domain [IPR006070]", "Z-binding domain [IPR042371]", "ZAP, helix turn helix N-terminal domain [IPR041360]", "ZAP, zinc finger [IPR040954]", "ZC3H15/TMA46 family, C-terminal [IPR032378]", "ZN598/Hel2, RING finger [IPR041888]", "ZN622/Rei1/Reh1, zinc finger C2H2-type [IPR041661]", "ZO-1, SH3 domain [IPR035597]", "ZU5 domain [IPR000906]", "Zasp-like motif [IPR006643]", "Zinc finger C2H2 AKAP95-type [IPR034736]", "Zinc finger C2H2-type [IPR013087]", "Zinc finger C2HC RNF-type [IPR034734]", "Zinc finger, B-box, chordata [IPR020457]", "Zinc finger, C2H2, LYAR-type [IPR014898]", "Zinc finger, C3HC-like [IPR012935]", "Zinc finger, C3HC4 RING-type [IPR018957]", "Zinc finger, CCCH-type [IPR000571]", "Zinc finger, CCHC-type [IPR001878]", "Zinc finger, CHHC-type [IPR012996]", "Zinc finger, CW-type [IPR011124]", "Zinc finger, CXXC-type [IPR002857]", "Zinc finger, ClpX C4-type [IPR010603]", "Zinc finger, DNA-directed DNA polymerase, family B, alpha [IPR015088]", "Zinc finger, FPG/IleRS-type [IPR010663]", "Zinc finger, FYVE-related [IPR017455]", "Zinc finger, GATA-type [IPR000679]", "Zinc finger, LIM-type [IPR001781]", "Zinc finger, MIZ-type [IPR004181]", "Zinc finger, MYM-type [IPR010507]", "Zinc finger, MYND-type [IPR002893]", "Zinc finger, PARP-type [IPR001510]", "Zinc finger, PHD-finger [IPR019787]", "Zinc finger, PHD-type [IPR001965]", "Zinc finger, RING-CH-type [IPR011016]", "Zinc finger, RING-type [IPR001841]", "Zinc finger, RanBP2-type [IPR001876]", "Zinc finger, Sec23/Sec24-type [IPR006895]", "Zinc finger, TFIIB-type [IPR013137]", "Zinc finger, TFIIS-type [IPR001222]", "Zinc finger, UBP-type [IPR001607]", "Zinc finger, UBR-type [IPR003126]", "Zinc finger, ZPR1-type [IPR004457]", "Zinc finger, ZZ-type [IPR000433]", "Zinc finger, double-stranded RNA binding [IPR022755]", "Zinc knuckle CX2CX3GHX4C [IPR025829]", "Zinc ribbon, NADH pyrophosphatase [IPR015376]", "Zinc-finger C2H2-type 11 [IPR041697]", "Zinc-finger CCCH domain [IPR041686]", "Zinc-ribbon domain [IPR026870]", "Zn-dependent metallo-hydrolase, RNA specificity domain [IPR011108]", "cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain [IPR003117]", "dUTPase, trimeric [IPR033704]", "dUTPase-like [IPR029054]", "eIF3 subunit M, C-terminal helix domain [IPR040750]", "eIF3B, RNA recognition motif [IPR034363]", "eIF3G, RNA recognition motif [IPR034240]", "eIF3h, C-terminal [IPR045810]", "eIF4H, RNA recognition motif [IPR034229]", "eRF1 domain 1/Pelota-like [IPR005140]", "eRF1 domain 2 [IPR005141]", "eRF1 domain 3 [IPR005142]", "hnRNP A0, RNA recognition motif 1 [IPR034801]", "hnRNP A1, RNA recognition motif 1 [IPR034845]", "hnRNP A1, RNA recognition motif 2 [IPR034803]", "hnRNP A2/B1, RNA recognition motif 1 [IPR034486]", "hnRNP A3, RNA recognition motif 1 [IPR034513]", "hnRNP A3, RNA recognition motif 2 [IPR034516]", "hnRNP DL, RNA recognition motif 1 [IPR034847]", "hnRNP-L, RNA recognition motif 1 [IPR035005]", "hnRNP-L, RNA recognition motif 2 [IPR035008]", "hnRNP-L, RNA recognition motif 3 [IPR034816]", "hnRNP-L, RNA recognition motif 4 [IPR034817]", "hnRNPAB, RNA recognition motif 1 [IPR034846]", "hnRNPH3, RNA recognition motif 2 [IPR034970]", "hnRNPH3, RNA recognition motif 3 [IPR034969]", "hnRNPM, RNA recognition motif 3 [IPR034990]", "hnRPLL, RNA recognition motif 1 [IPR034985]", "hnRPLL, RNA recognition motif 2 [IPR034986]", "hnRPLL, RNA recognition motif 3 [IPR034983]", "hnRPLL, RNA recognition motif 4 [IPR034987]", "mRNA (guanine-N(7))-methyltransferase domain [IPR004971]", "mRNA decay factor PAT1 domain [IPR019167]", "mRNA splicing factor Cwf21 domain [IPR013170]", "p115RhoGEF, RGS domain [IPR037887]", "p21 activated kinase binding domain [IPR033923]", "p21-activated kinase 2, catalytic domain [IPR035064]", "p53 transactivation domain [IPR013872]", "p53, DNA-binding domain [IPR011615]", "p53, tetramerisation domain [IPR010991]", "p54nrb, RNA recognition motif 1 [IPR034552]", "rRNA-processing arch domain [IPR025696]", "snRNP70, RNA recognition motif [IPR034143]", "tRNA methyltransferase TRM10-type domain [IPR028564]", "tRNA methyltransferase TRMD/TRM10-type domain [IPR016009]", "tRNA pseudouridylate synthase B, C-terminal [IPR032819]", "tRNA synthetase, B5-domain [IPR005147]", "tRNA synthetases class I, catalytic domain [IPR032678]", "tRNA(Met) cytidine acetyltransferase TmcA, N-terminal [IPR013562]", "tRNA-binding domain [IPR002547]", "tRNA-guanine(15) transglycosylase-like [IPR002616]", "tRNase Z endonuclease [IPR027794]", "v-SNARE, coiled-coil homology domain [IPR042855]", "von Willebrand factor, type A [IPR002035]"], "available_proteins": ["AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAP2", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTN1", "ACTN2", "ACTN4", "ADA", "ADAR", "ADD1", "ADH5", "ADK", "ADNP", "ADRM1", "ADSL", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AK4", "AKAP1", "AKAP12", "AKAP8", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALKBH5", "ALYREF", "AMOT", "ANAPC5", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANP32A", "ANP32B", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP3B1", "AP3D1", "AP3M1", "APEH", "APEX1", "APMAP", "APRT", "AQR", "ARCN1", "ARF4", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGAP5", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL8B", "ARMCX3", "ARMT1", "AS3MT", "ASAH1", "ASCC2", "ASCC3", "ASNA1", "ASNS", "ASPH", "ASPM", "ATAD1", "ATAD3A", "ATAD3B", "ATAD5", "ATIC", "ATL2", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "ATP6V1H", "ATP7B", "ATRX", "ATXN10", "ATXN2L", "AUP1", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAP18", "BAZ1A", "BAZ1B", "BCAP31", "BCL10", "BCS1L", "BET1", "BIRC6", "BLVRA", "BLVRB", "BMS1", "BOP1", "BRD2", "BRIX1", "BSG", "BTF3", "BZW1", "BZW2", "C11orf58", "C1orf35", "C2CD2", "C2CD5", "CACUL1", "CACYBP", "CAD", "CALU", "CAND1", "CAP1", "CAPN1", "CAPRIN1", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP2", "CASP3", "CASP6", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCNB1", "CD276", "CD2AP", "CD2BP2", "CD47", "CDC23", "CDC37", "CDC42", "CDC5L", "CDC73", "CDCA8", "CDK1", "CDK13", "CDK2", "CDK4", "CDK6", "CDKAL1", "CDKN2AIP", "CEBPZ", "CELF1", "CELF2", "CENPV", "CEP170", "CEP44", "CEP55", "CERS2", "CFAP20", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHD1", "CHD1L", "CHD4", "CHEK2", "CHERP", "CHID1", "CHORDC1", "CHRAC1", "CHUK", "CIAPIN1", "CIRBP", "CISD2", "CIZ1", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP2", "CLCN3", "CLCN7", "CLIC1", "CLIC4", "CLINT1", "CLP1", "CLPB", "CLPX", "CLTC", "CLUH", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNOT1", "CNPY2", "COA3", "COASY", "COIL", "COL4A3BP", "COMMD10", "COMMD2", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "CORO1C", "COTL1", "COX2", "COX6C", "CPD", "CPNE1", "CPNE3", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT2", "CRK", "CRKL", "CRYZL1", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNBL1", "CTPS1", "CTPS2", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC22", "CWF19L1", "CXADR", "CYB5B", "CYB5D2", "CYB5R3", "CYFIP1", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DCAF13", "DCTN1", "DDA1", "DDB1", "DDI2", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENR", "DFFA", "DGCR8", "DHCR24", "DHFR", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX40", "DHX8", "DHX9", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIP2B", "DIS3", "DIS3L2", "DKC1", "DLAT", "DLD", "DLST", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1", "DNM1L", "DNM2", "DNMT1", "DNTTIP2", "DPF2", "DPM1", "DPP9", "DPYSL2", "DPYSL3", "DRG1", "DRG2", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "EARS2", "EBP", "ECE1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFL1", "EFTUD2", "EHD1", "EHMT1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B3", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A3", "EIF4B", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP3", "EMC1", "EMC7", "EMC8", "EMD", "EML4", "ENDOD1", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPHX1", "EPHX2", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERC1", "ERCC2", "ERCC6L", "ERGIC3", "ERI1", "ERLIN2", "ERMP1", "ERP29", "ERP44", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC4", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EYA3", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAHD2A", "FAM208A", "FAM3C", "FAM49B", "FAM8A1", "FAM91A1", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FBXO22", "FDFT1", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FLCN", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNBP4", "FNDC3A", "FOXC1", "FOXRED1", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GAK", "GALK1", "GALNT1", "GALNT2", "GANAB", "GAPDH", "GAPVD1", "GARS", "GART", "GATAD2A", "GATAD2B", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLM", "GCN1", "GDPD1", "GEMIN5", "GFM1", "GFPT1", "GGCT", "GGCX", "GHITM", "GIGYF2", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLTP", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GNS", "GOLGB1", "GOPC", "GOT1", "GOT2", "GPATCH4", "GPD2", "GPI", "GPKOW", "GPS1", "GPT2", "GRB2", "GRHPR", "GRSF1", "GRWD1", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2E1", "GTF3C1", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP4", "GUSB", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDGFL2", "HDLBP", "HEATR1", "HECTD1", "HELLS", "HELZ", "HERC2", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HP1BP3", "HPRT1", "HS1BP3", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA4", "HSPA4L", "HSPB1", "HSPBP1", "HSPH1", "HTATSF1", "HUWE1", "IARS", "IARS2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "ILF2", "ILF3", "ILKAP", "ILVBL", "IMP3", "IMPDH2", "INA", "INCENP", "INF2", "INTS3", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IRF2BPL", "IRS4", "ISCU", "ISOC1", "ISYNA1", "ITCH", "ITGB1", "ITPK1", "IVD", "KARS", "KAT7", "KCTD12", "KCTD5", "KDELC2", "KDM1A", "KDM1B", "KDM3B", "KHDRBS1", "KHSRP", "KIF11", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LBR", "LCLAT1", "LDHA", "LDHB", "LEMD3", "LENG8", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRCH2", "LRPAP1", "LRPPRC", "LRRC47", "LSG1", "LSM12", "LSM14A", "LSM14B", "LSM2", "LSM6", "LSS", "LTA4H", "LTN1", "LYAR", "LYPLA1", "M6PR", "MACF1", "MAGED2", "MAK16", "MANF", "MAP2K1", "MAP2K2", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARK2", "MARS", "MAT2A", "MAT2B", "MATR3", "MAVS", "MCAT", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED25", "MEPCE", "METTL13", "MFF", "MFN2", "MFSD10", "MIA3", "MICU1", "MICU2", "MID1", "MINDY3", "MIPEP", "MKI67", "MLEC", "MMAB", "MMS19", "MOGS", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPP2", "MPP6", "MPRIP", "MPST", "MRE11", "MRPL11", "MRPL12", "MRPL15", "MRPL2", "MRPL39", "MRPL44", "MRPL45", "MRPL46", "MRPL58", "MRPL9", "MRPS10", "MRPS23", "MRPS25", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR6", "MTOR", "MTPAP", "MTX1", "MTX2", "MTX3", "MUT", "MVD", "MVK", "MYEF2", "MYH10", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA40", "NAA50", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NARS", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH2", "NCBP1", "NCK1", "NCL", "NCLN", "NCSTN", "NDUFA10", "NDUFA6", "NDUFA8", "NDUFA9", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4", "NEFL", "NEFM", "NEK9", "NELFA", "NELFE", "NEMF", "NENF", "NES", "NFS1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPSNAP2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NME1", "NME2", "NMT1", "NNT", "NOC3L", "NOC4L", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP2", "NOP56", "NOP58", "NOSIP", "NOVA2", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSUN2", "NSUN5", "NSUN6", "NTPCR", "NUB1", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDCD2", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUF2", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP35", "NUP50", "NUP54", "NUP62", "NUP98", "NUTF2", "NVL", "NXF1", "NXN", "OCIAD1", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC3", "OSBP", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OXA1L", "OXSR1", "P3H1", "P4HA1", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAK2", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PASK", "PATL1", "PBDC1", "PBK", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCLAF", "PCM1", "PCNA", "PCYOX1", "PDCD11", "PDCD4", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDXK", "PEF1", "PELP1", "PEPD", "PES1", "PEX14", "PFAS", "PFKL", "PFKM", "PFKP", "PGD", "PGLS", "PGM1", "PGM2", "PGM3", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF2", "PHF3", "PHF6", "PHGDH", "PHIP", "PI4K2A", "PICALM", "PIH1D1", "PIK3C2A", "PIN1", "PIN4", "PINX1", "PIR", "PITHD1", "PITRM1", "PKM", "PKMYT1", "PKN2", "PLCG1", "PLD3", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPO", "PNPT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2E", "POLR2G", "POLR3A", "POLRMT", "POP1", "POR", "PPAN", "PPAT", "PPIB", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP3CA", "PPP4C", "PPP4R1", "PPP5C", "PQBP1", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREP", "PREPL", "PRKAA1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSPC1", "PTBP1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPN1", "PTPN11", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PWP2", "PXN", "PYCR1", "PYCR2", "QARS", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB21", "RAB24", "RAB34", "RAB35", "RAB39A", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB8B", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RAD21", "RAD23B", "RAD50", "RAD51AP1", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RASA1", "RAVER1", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM8A", "RBMX", "RBMXL1", "RBP1", "RCL1", "RCN1", "RCN2", "RDX", "RECQL", "RECQL4", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIF1", "RNASEH2A", "RNASEH2B", "RNF114", "RNF14", "RNF40", "RNMT", "RNPEP", "RNPS1", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP3", "RPF2", "RPL10", "RPL11", "RPL12", "RPL14", "RPL18", "RPL18A", "RPL19", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL30", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPP25L", "RPRD1A", "RPRD1B", "RPS10", "RPS11", "RPS12", "RPS13", "RPS2", "RPS20", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS9", "RPSA", "RRBP1", "RREB1", "RRM1", "RRP12", "RSF1", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTN4IP1", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMHD1", "SAMM50", "SAR1A", "SARNP", "SARS", "SARS2", "SART3", "SBDS", "SC5D", "SCCPDH", "SCML2", "SCO2", "SCP2", "SCRIB", "SDCBP", "SDE2", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEL1L", "SENP3", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SETD7", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGTA", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHMT1", "SHMT2", "SIN3A", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC16A1", "SLC25A12", "SLC25A13", "SLC25A24", "SLC27A4", "SLC3A2", "SLC4A1AP", "SLC9A3R1", "SLFN11", "SLIRP", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMS", "SMU1", "SMYD3", "SMYD5", "SNAP23", "SNAP29", "SND1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SOD2", "SON", "SORD", "SPAG9", "SPART", "SPATA5L1", "SPC25", "SPECC1L", "SPEN", "SPPL2A", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SRCAP", "SREK1", "SRI", "SRM", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSRP1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STIM2", "STIP1", "STK4", "STOML2", "STRBP", "STRN", "STUB1", "STX10", "STX12", "STX17", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SULT2A1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACC3", "TAF15", "TAGLN2", "TARDBP", "TARS", "TARS2", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCB", "TBCD", "TBCE", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TDP2", "TDRKH", "TECR", "TELO2", "TERF2IP", "TES", "TEX10", "TFAM", "TFG", "TFIP11", "TFRC", "THOC1", "THOC3", "THOP1", "THUMPD1", "THUMPD3", "TIA1", "TIAL1", "TIMELESS", "TIMM13", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TKT", "TLN1", "TMED10", "TMED2", "TMED7", "TMEM205", "TMEM97", "TMPO", "TMPO", "TMPPE", "TMTC3", "TMX1", "TMX2", "TMX4", "TNPO1", "TNPO2", "TOE1", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOX4", "TP53", "TP53BP1", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRIM21", "TRIM25", "TRIM27", "TRIM28", "TRIP12", "TRIP13", "TRMT10C", "TRMT11", "TRMT2A", "TROVE2", "TRUB1", "TSC2", "TSFM", "TSG101", "TSR1", "TSTA3", "TTC4", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA6", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE2V1", "UBE3C", "UBE4A", "UBLCP1", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UCHL5", "UCK2", "UGDH", "UGGT1", "UHRF1", "UMPS", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCRC1", "UQCRC2", "UQCRFS1", "URB1", "UROD", "USO1", "USP10", "USP11", "USP14", "USP19", "USP28", "USP33", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP20", "UTRN", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VCP", "VEZT", "VIM", "VPS13A", "VPS18", "VPS29", "VPS4A", "VPS51", "VPS53", "VRK1", "VRK3", "WAPL", "WARS", "WBP2", "WDHD1", "WDR18", "WDR3", "WDR36", "WDR43", "WDR46", "WFS1", "WIZ", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YBX1", "YKT6", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZDHHC13", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM4", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF598", "ZNF622", "ZNF638", "ZNF687", "ZPR1", "ZRANB2", "ZYX"], "leading_proteins": ["ABCB10", "ABCB7", "ABCC1", "ABCC4", "ABCF1", "ABCF3", "ACOX3", "ACTN2", "AKT1", "AKT2", "ANKFY1", "ANKHD1", "ANLN", "AP1B1", "ARFIP2", "ARHGEF2", "ARHGEF7", "ATAD1", "ATAD3A", "ATP1A1", "ATP2B1", "ATP2C1", "ATRX", "BAP18", "BCL10", "BCS1L", "BRIX1", "CACUL1", "CAP1", "CASP3", "CDK13", "CHD1L", "CIRBP", "CNNM3", "COL4A3BP", "COPB2", "CUL1", "CUL2", "CUL3", "CUL5", "CXADR", "CYFIP1", "DDX39A", "DDX42", "DDX50", "DDX55", "DEK", "DHX29", "DHX30", "DHX36", "DIAPH3", "DIS3L2", "DNAJA3", "DNAJC3", "DNMT1", "DRG2", "EHD1", "EPRS", "ERAL1", "ERCC6L", "ERMP1", "ETFB", "FAF2", "FKBP7", "FKBP9", "FXR2", "GARS", "GCFC2", "GFPT1", "GINS2", "GINS3", "GLOD4", "GMPPA", "GMPPB", "GNL2", "GNL3L", "GTPBP10", "GTPBP4", "H1F0", "H1FX", "H2AFY2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HLTF", "HNRNPU", "HSP90AB1", "IGF2BP2", "ILKAP", "IPO11", "KCTD12", "KCTD5", "KDM1A", "KDM1B", "KIF1A", "KIF23", "KIF2A", "KIF2C", "KTN1", "LDHB", "LETM1", "LRRC47", "MAP2K2", "MAP3K7", "MARK2", "MARS", "MDH1", "MDH2", "MIPEP", "MOSPD2", "MRPL45", "MRPS5", "MSN", "MTA1", "MTA2", "MTIF2", "MTOR", "MTX1", "MVD", "MVK", "MYH9", "NDUFA6", "NDUFS1", "NECAP1", "NEFL", "NLE1", "NNT", "NONO", "NPTN", "NRBP1", "NUCB2", "OCRL", "OLA1", "OXSR1", "P4HB", "PAFAH1B3", "PCBP2", "PDHB", "PDIA3", "PDIA4", "PDK3", "PDLIM1", "PHB2", "PKMYT1", "PNP", "POLR1A", "PPAT", "PPM1F", "PPP1CA", "PPP3CA", "PRDX2", "PRDX3", "PRDX6", "PRKAR1A", "PRRC2A", "PSMC1", "PSMC6", "PSMD14", "QKI", "RABGAP1", "RACGAP1", "RASA1", "RBP1", "RECQL4", "ROCK2", "RPF2", "RPL24", "RPL28", "RPL7", "RPLP0", "RTN3", "RUFY1", "RUVBL1", "S100A11", "SAMHD1", "SARNP", "SARS", "SARS2", "SCML2", "SEC63", "SEPT6", "SEPT9", "SERPINH1", "SFPQ", "SHMT2", "SLTM", "SMARCA1", "SMARCA5", "SMARCC2", "SMC2", "SMC4", "SMC5", "SNRPD1", "SNX1", "SRPRA", "STK4", "STOML2", "TARS2", "TDRKH", "TFRC", "TIMM13", "TKT", "TMPO", "TMPPE", "TRAP1", "TUBB2A", "TUBB4A", "TUBB4B", "TUBGCP3", "TXNDC5", "UBA1", "UBE2S", "UNC119B", "VAPB", "VCP", "VPS4A", "WARS", "XPOT", "YME1L1", "YTHDC2", "ZNF318", "ZNF622"]} \ No newline at end of file diff --git a/interpro_family/advanced/idx2term.json b/interpro_family/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_family/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_family/basic/idx2term.json b/interpro_family/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_family/basic/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_family/consensus.joblib b/interpro_family/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..3e4426c98740325a99763d9723dfe75054bc819e --- /dev/null +++ b/interpro_family/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1b5af4e3f2a545d72b996b1407283ee7bedb599b8c35439b176dae587c649595 +size 677257 diff --git a/interpro_family/df_merge.tsv b/interpro_family/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..0f263075aa3edf5549be845d7b91d0cee24c5dbb --- /dev/null +++ b/interpro_family/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Glutathione Transferase family [IPR040079] 1 10 2.584429735059203 0.0097540177028396 2.6650485436893203 9.45388349514563 0.453215617797485 0.4615521029697171 1.6850115229858122 1.256172900264393 0.947748980990547 0.2879961408071128 0.0013730874852706 0.0639684350193291 0.1216867716169547 0.0416823512829171 0.1415197041538892 diff --git a/interpro_family/metrics.json b/interpro_family/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..06e053dbaec5521add802eebce84fb12fb5fa026 --- /dev/null +++ b/interpro_family/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2772, + "annotations_size": 2182, + "title": "Average number of proteins per term", + "value": 1.2768102658111824 +} \ No newline at end of file diff --git a/interpro_family/paths.json b/interpro_family/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..bf96de58775b7c2735963069866a4d6166cb088d --- /dev/null +++ b/interpro_family/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_family/fragment/C321/C321_val_log2fc"} \ No newline at end of file diff --git a/interpro_family/result.tsv b/interpro_family/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..f614b5bc37221e9914cb691a336ff9765e444d15 --- /dev/null +++ b/interpro_family/result.tsv @@ -0,0 +1,86 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mitochondrial inner membrane translocase complex, subunit Tim17 [IPR005678] 0.9978339350180504 2.6966707780757604 0.0070036474801833 0.9999997813349464 0.015593835512 2 O60830 1 +Cytochrome P450 [IPR001128] 0.9916967509025272 2.6706600345048495 0.0075702275490601 0.9999999370595796 0.0166012427256775 2 Q6UW02 1 +Glutathione Transferase family [IPR040079] 0.8848022300116235 2.584429735059203 0.0097540177028396 0.9999999994854588 0.0203084605225154 10 Q13505 1 +Intracellular lipid binding protein [IPR031259] 0.9711191335740068 2.5829405517627073 0.0097962201343093 0.9999999995311508 0.0203768849695548 2 P09455 1 +Haem oxygenase [IPR002051] 0.9610108303249096 2.5395644357449414 0.0110990598030693 0.9999999999734912 0.0225075729463729 2 P30519 1 +Haem oxygenase-like [IPR016053] 0.9610108303249096 2.5395644357449414 0.0110990598030693 0.9999999999734912 0.0225075729463729 2 P30519 1 +Mitochondrial carrier UCP-like [IPR002030] 0.8859205776173277 2.211524457190486 0.0269995401650158 1.0 0.0454225109021314 2 Q9H2D1 1 +Peroxisomal acyl-coenzyme A oxidase [IPR034171] 0.8826714801444038 2.1971041980219552 0.0280130053747811 1.0 0.0467311756328535 2 O15254 1 +Acyl-CoA oxidase [IPR012258] 0.8826714801444038 2.1971041980219552 0.0280130053747811 1.0 0.0467311756328535 2 O15254 1 +Arfaptin family [IPR030798] 0.8570397111913339 2.082716422831926 0.0372770795878114 1.0 0.0584328934343423 2 P53365 1 +Twinfilin [IPR028458] 0.8472924187725621 2.038932127033629 0.0414568019818069 1.0 0.0636585094470813 2 Q6IBS0 1 +Torsin-1A-interacting protein 1/2 [IPR008662] 0.8317689530685904 1.9688917594580488 0.0489655220488187 1.0 0.0731298898771543 2 Q5JTV8 1 +Gamma-tubulin complex component protein [IPR007259] 0.8212996389891682 1.9214486289068131 0.0546751728631615 1.0 0.079587209598011 2 Q96CW5 1 +Dephospho-CoA kinase [IPR001977] 0.8187725631768934 1.9099728036231325 0.0561367150889355 1.0 0.0813889118432275 2 Q13057 1 +Mitochondrial import inner membrane translocase subunit Tim8/13 [IPR039238] 0.8061371841155216 1.8524588006595024 0.063959968418191 1.0 0.0903305185038789 2 Q9Y5L4 1 +Cleft lip and palate transmembrane protein 1-like protein [IPR030434] 0.7725631768953047 1.6986412367154216 0.0893868017151073 1.0 0.1172832238979941 2 Q96KA5 1 +Cleft lip and palate transmembrane 1 [IPR008429] 0.7725631768953047 1.6986412367154216 0.0893868017151073 1.0 0.1172832238979941 2 Q96KA5 1 +Prenylated rab acceptor PRA1 [IPR004895] 0.7711191335740049 1.6919965865059343 0.0906466244697083 1.0 0.1185086486476355 2 O75915 1 +Tyrosine-tRNA ligase [IPR002307] 0.7678700361010807 1.6770384197905552 0.0935349692239853 1.0 0.1215564638753638 2 Q9Y2Z4 1 +Oligosaccharyl transferase, STT3 subunit [IPR003674] 0.7675090252707557 1.6753757552254624 0.0938605304394304 1.0 0.1218344303502898 2 Q8TCJ2 1 +Small GTPase superfamily, ARF type [IPR024156] 0.7548736462093838 1.6171063565721655 0.1058553249978293 1.0 0.1347969055069275 2 P40616 1 +Ribosomal protein S5 [IPR000851] 0.7530685920577591 1.6087708690700924 0.107666452901828 1.0 0.1365067985077216 2 P82675 1 +Ribosomal protein S8e/ribosomal biogenesis NSA2 [IPR022309] 0.7480144404332105 1.5854179628732477 0.1128714025851591 1.0 0.141809465035769 2 O95478 1 +Translation initiation factor IF- 2 [IPR015760] 0.7382671480144377 1.5403294840734298 0.1234800603826415 1.0 0.1523083616477806 2 P46199 1 +Linker histone H1/H5 [IPR005819] 0.7202746657029107 1.373828803036019 0.1694948369331275 1.0 0.1979510838179498 5 Q92522,P07305,P10412,P16403 4 +Translin family [IPR002848] 0.6797833935018014 1.2692304554921263 0.2043588817791364 1.0 0.2302070624894557 2 Q15631 1 +Prefoldin alpha-like [IPR004127] 0.674007220216603 1.2424977138286997 0.2140529834672504 1.0 0.238297760166092 2 Q99471 1 +cAMP-dependent protein kinase regulatory subunit [IPR012198] 0.6653429602888048 1.202451344936469 0.2291887062758046 1.0 0.252570584390811 2 P10644 1 +Transmembrane protein GPR107/GPR108-like [IPR009637] 0.8145250864689179 1.1990240993601884 0.2305185749876388 1.0 0.2539078902690701 3 Q8NBN3 1 +Serpin family [IPR000215] 0.6628158844765306 1.1907854679883183 0.2337378151930698 1.0 0.257064472152862 2 P50454 1 +Prohibitin [IPR000163] 0.6624548736462057 1.1891195042647815 0.2343926442918804 1.0 0.257654785816062 2 Q99623 1 +Peroxiredoxin, AhpC-type [IPR024706] 0.6617328519855556 1.185788034449426 0.2357060180341603 1.0 0.2589680419690523 2 P32119 1 +Serine hydroxymethyltransferase [IPR001085] 0.6451263537906096 1.1093610108724934 0.2672744749855842 1.0 0.2924738738307647 2 P34897 1 +Protein phosphatase 2C family [IPR015655] 0.7616222904676202 1.066767624578038 0.286076781567953 1.0 0.3127352391689747 4 Q9H0C8,P49593 2 +Kinesin-like protein [IPR027640] 0.5573312721216959 0.9343741805241694 0.3501109115091676 1.0 0.3796928473722682 8 O00139,Q02241,Q12756 3 +Ezrin/radixin/moesin [IPR011174] 0.7415268134999096 0.9335502387907456 0.3505359440593913 1.0 0.3799649428403338 3 P26038 1 +LanC-like protein, eukaryotic [IPR020464] 0.5909747292418723 0.8645548181340337 0.3872831803114629 1.0 0.4181355266895656 2 O43813 1 +Lanthionine synthetase C-like [IPR007822] 0.5909747292418723 0.8645548181340337 0.3872831803114629 1.0 0.4181355266895656 2 O43813 1 +Glycogen/starch/alpha-glucan phosphorylase [IPR011833] 0.588447653429598 0.8533755857301134 0.3934510559916129 1.0 0.4239556563820737 2 P06737 1 +Glycosyl transferase, family 35 [IPR000811] 0.588447653429598 0.8533755857301134 0.3934510559916129 1.0 0.4239556563820737 2 P06737 1 +Histone H2A [IPR002119] 0.7175729702321781 0.8484300111244578 0.3961985349191448 1.0 0.426284616959356 3 Q9P0M6 1 +Intracellular chloride channel [IPR002946] 0.5837545126353743 0.8326905822058367 0.4050192573261819 1.0 0.4351314719279808 2 Q9Y696 1 +26S proteasome regulatory subunit P45-like [IPR005937] 0.5428226814026577 0.7250587006557537 0.4684160193779065 1.0 0.501267167377436 6 P62191,P62333,P43686 3 +Mesoderm induction early response protein/metastasis-associated protein [IPR040138] 0.5581227436823052 0.7217363836578994 0.4704565683110948 1.0 0.5032040353209848 2 Q13330 1 +Ribosomal protein L3 [IPR000597] 0.5490974729241822 0.6836165908114392 0.4942173054267214 1.0 0.5265537892778838 2 P09001 1 +Type 1 protein exporter [IPR039421] 0.6662684189507014 0.6720103846832789 0.5015770852525818 1.0 0.534134309429543 3 O75027 1 +Aminoacyl-tRNA synthetase, class Ic [IPR002305] 0.6608884073672731 0.6541131411366136 0.5130389157434982 1.0 0.5455413811658446 3 Q9Y2Z4,P54577 2 +Peptidase M3A/M3B [IPR045090] 0.6570982767949234 0.6415865782722872 0.5211416498745343 1.0 0.5530793190789075 3 Q99797 1 +Peptidase C14 family [IPR002398] 0.6417600462103835 0.5916315512063265 0.5540973412940866 1.0 0.5871978624107319 3 P42574 1 +DNA-directed RNA polymerase, subunit beta-prime [IPR045867] 0.6348565752054931 0.569561893595119 0.5689748802551906 1.0 0.6020869004446294 3 O95602 1 +26S Proteasome non-ATPase regulatory subunit 12/COP9 signalosome complex subunit 4 [IPR040134] 0.4992779783393439 0.4852032696184958 0.6275321629767008 1.0 0.6602098262368182 2 Q9BT78 1 +Ubiquitin-activating enzyme E1 [IPR018075] 0.4989169675090191 0.4838545128901917 0.6284891242953294 1.0 0.6608979610662211 2 P22314 1 +Heat shock protein Hsp90 family [IPR001404] 0.5868803853317258 0.4722954870277888 0.6367158911733246 1.0 0.6672978263881817 4 Q12931,P08238 2 +Snf7 family [IPR005024] 0.5616221310065779 0.3554158970248774 0.722278041185273 1.0 0.7501240770424872 3 Q8WUX9 1 +Calreticulin/calnexin [IPR001580] 0.5505182581020889 0.3267844777327577 0.7438309004399746 1.0 0.7710399167506055 3 O14967 1 +Protein disulphide isomerase [IPR005792] 0.549378485635492 0.3239116591723985 0.7460049167297842 1.0 0.7729262717494725 3 P13667 1 +Vesicle-associated membrane-protein-associated protein [IPR016763] 0.431046931407937 0.2609805471787595 0.7941075086446103 1.0 0.8200390837021012 2 O95292 1 +RuvB-like [IPR027238] 0.4296028880866373 0.2569972183136745 0.7971809204379441 1.0 0.822823447680035 2 Q9Y265 1 +Proteasome B-type subunit [IPR023333] 0.3865912168329387 0.2421884519005822 0.8086341427849364 1.0 0.8314984446544446 7 P49721 1 +DnaJ homolog subfamily A member 1/2-like [IPR044713] 0.4220216606498121 0.2366654338012724 0.8129163530216146 1.0 0.8351805966954134 2 O60884 1 +Ribosomal protein L7/L30 [IPR039699] 0.4162454873646136 0.221839297069003 0.8244389869061615 1.0 0.8449628320475548 2 P18124 1 +Ribosomal protein L7, eukaryotic [IPR005998] 0.4162454873646136 0.221839297069003 0.8244389869061615 1.0 0.8449628320475548 2 P18124 1 +Thiolase [IPR002155] 0.3981854020771604 0.2211029516240134 0.8250122720691886 1.0 0.8451534167394222 5 P24752,P55084 2 +Ubiquitin/SUMO-activating enzyme E1 [IPR000011] 0.4990971469844752 0.2104589206812786 0.8333095101700054 1.0 0.8528524161308405 3 P22314,Q9UBE0 2 +Isocitrate dehydrogenase NAD-dependent [IPR004434] 0.4962080173347857 0.2047744963899665 0.8377483136971151 1.0 0.8569933523146297 3 P51553,O43837 2 +Synaptobrevin [IPR001388] 0.3985559566786945 0.1801004279353381 0.8570737266581336 1.0 0.8747122879177023 2 P51809 1 +Septin [IPR016491] 0.3787793426569537 0.1779813235389526 0.858737643212528 1.0 0.8760007187890304 5 Q9UHD8,Q14141 2 +Tubulin [IPR000217] 0.3559066808906926 0.145837185258275 0.884049920122407 1.0 0.8984298479796827 6 P68371,P04350,Q13885 3 +Beta tubulin [IPR002453] 0.3559066808906926 0.145837185258275 0.884049920122407 1.0 0.8984298479796827 6 P68371,P04350,Q13885 3 +Serine-tRNA ligase, type1 [IPR002317] 0.3815884476534232 0.1453551383833572 0.8844304827957647 1.0 0.8984298479796827 2 P49591 1 +Small GTPase superfamily, ARF/SAR type [IPR006689] 0.3509871009860891 0.1364855774640128 0.8914374253727793 1.0 0.9046652134001169 6 Q9NR31,P40616,P18085 3 +Fimbrin/Plastin [IPR039959] 0.3765342960288741 0.1360111081307291 0.891812499552544 1.0 0.9046652134001169 2 Q14651 1 +Nuclear pore complex protein [IPR026054] 0.3664259927797774 0.118695032841744 0.9055169719465406 1.0 0.9168621961890262 2 P35658 1 +Protein PRRC2 [IPR033184] 0.3588447653429541 0.1068914561663696 0.9148750913480724 1.0 0.9254786505894732 2 P48634 1 +Phenylalanine-tRNA ligase, class IIc, beta subunit [IPR045060] 0.3530685920577556 0.0985651700117353 0.9214835256191208 1.0 0.9313001634557302 2 Q8N1G4 1 +Synthesis of cytochrome c oxidase, Sco1/Sco2 [IPR017276] 0.3480144404332067 0.0917429380103054 0.9269022816249216 1.0 0.9359096615018874 2 O75880 1 +Copper chaperone SCO1/SenC [IPR003782] 0.3480144404332067 0.0917429380103054 0.9269022816249216 1.0 0.9359096615018874 2 O75880 1 +Tumour protein D52 [IPR007327] 0.3465703971119069 0.0898718541032595 0.9283890477917413 1.0 0.9369772906020256 2 P55327 1 +Threonine-tRNA ligase, class IIa [IPR002320] 0.3447653429602824 0.0875812337741125 0.9302095181342068 1.0 0.9383805679929912 2 Q9BW92 1 +L-lactate/malate dehydrogenase [IPR001557] 0.4039017341040576 0.08620682132637 0.9313020082627534 1.0 0.9390485129525544 4 P07195,P40925,P40926 3 +Importin beta family [IPR040122] 0.3050234911456445 0.0639028524575942 0.9490475809907416 1.0 0.9551761170303495 5 O00410,Q92973,Q8TEX9,O14787 4 +Myristoylated alanine-rich C-kinase substrate MARCKS [IPR002101] 0.2693140794223753 0.0321145213417289 0.9743807230276478 1.0 0.979087741422487 2 P49006 1 +Structural maintenance of chromosomes protein [IPR024704] 0.3283959537572331 0.0315164373383004 0.9748576835562244 1.0 0.979087741422487 4 O95347,Q9NTJ3,Q14683 3 +Cullin [IPR045093] 0.2580411998554394 0.028944899682249 0.9769085358404488 1.0 0.9805034154571568 5 Q13616,Q93034,Q13617,Q13618 4 +Initiation factor 4G [IPR045208] 0.2509931383170738 0.0178472659655618 0.9857606979662636 1.0 0.988933261132132 3 O43432,Q04637 2 diff --git a/interpro_family/selections.json b/interpro_family/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..bc4cbf121816e30022999a7463db108883afb661 --- /dev/null +++ b/interpro_family/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["(Uracil-5)-methyltransferase family [IPR010280]", "-alpha-acetyltransferase 35, NatC auxiliary subunit [IPR007244]", "1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, eukaryotes [IPR027496]", "1-Cys peroxiredoxin [IPR045020]", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [IPR028380]", "14-3-3 protein [IPR000308]", "14-3-3 theta [IPR042584]", "2-amino-3-ketobutyrate coenzyme A ligase [IPR011282]", "2-deoxynucleoside 5-phosphate N-hydrolase 1, DNPH1 [IPR028607]", "2-oxoglutarate dehydrogenase E1 component [IPR011603]", "2-phosphoglycolate phosphatase, eukaryotic [IPR006349]", "26S Proteasome non-ATPase regulatory subunit 1 [IPR035266]", "26S Proteasome non-ATPase regulatory subunit 11 [IPR035295]", "26S Proteasome non-ATPase regulatory subunit 12 [IPR035297]", "26S Proteasome non-ATPase regulatory subunit 12/COP9 signalosome complex subunit 4 [IPR040134]", "26S Proteasome non-ATPase regulatory subunit 13 [IPR035298]", "26S Proteasome non-ATPase regulatory subunit 14 [IPR035299]", "26S Proteasome non-ATPase regulatory subunit 6 [IPR035268]", "26S Proteasome non-ATPase regulatory subunit 7/8 [IPR033858]", "26S Proteasome regulatory subunit 4 [IPR035244]", "26S Proteasome regulatory subunit 6A [IPR035254]", "26S Proteasome regulatory subunit 6B [IPR035256]", "26S Proteasome regulatory subunit 7 [IPR035245]", "26S proteasome non-ATPase regulatory subunit 10-like [IPR039334]", "26S proteasome non-ATPase regulatory subunit 3 [IPR035267]", "26S proteasome non-ATPase regulatory subunit Rpn12 [IPR006746]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit [IPR016643]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit [IPR016642]", "26S proteasome regulatory subunit 10B [IPR035263]", "26S proteasome regulatory subunit P45-like [IPR005937]", "26S proteasome regulatory subunit Rpn7/COP9 signalosome complex subunit 1 [IPR019585]", "28S ribosomal protein S10, mitochondrial [IPR040055]", "28S ribosomal protein S17, mitochondrial [IPR039193]", "28S ribosomal protein S25, mitochondrial [IPR040049]", "28S ribosomal protein S27, mitochondrial [IPR019266]", "3'-5' RNA helicase YTHDC2-like [IPR031083]", "3-hydroxyacyl-CoA dehydrogenase [IPR022694]", "3-hydroxyisobutyrate dehydrogenase [IPR011548]", "3-hydroxyisobutyrate dehydrogenase-related [IPR015815]", "3-ketodihydrosphingosine reductase KDSR-like [IPR045022]", "3-oxo-5-alpha-steroid 4-dehydrogenase/very-long-chain enoyl-CoA reductase [IPR039357]", "39S ribosomal protein L40, mitochondrial [IPR039145]", "39S ribosomal protein L46, mitochondrial [IPR040008]", "40S Ribosomal protein S10 [IPR037447]", "40S ribosomal protein S1/3, eukaryotes [IPR027500]", "40S ribosomal protein SA [IPR027504]", "4F2 cell-surface antigen heavy chain [IPR042280]", "5'-3' exoribonuclease [IPR027073]", "5'-3' exoribonuclease type 2 [IPR017151]", "5'-AMP-activated protein kinase subunit gamma-1 [IPR039166]", "5'-deoxynucleotidase YfbR/HDDC2 [IPR039356]", "5-lipoxygenase-activating protein [IPR001446]", "50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a [IPR028877]", "6-Phosphogluconolactonase [IPR039104]", "6-phosphogluconate dehydrogenase [IPR006183]", "6-phosphogluconate dehydrogenase, decarboxylating [IPR006113]", "60S acidic ribosomal protein P0 [IPR030670]", "60S ribosomal protein L18a/ L20, eukaryotes [IPR021138]", "60S ribosomal protein L19 [IPR039547]", "60S ribosomal protein L35 [IPR045059]", "60S ribosomal protein L6E [IPR000915]", "60kDa SS-A/Ro ribonucleoprotein [IPR040322]", "A-kinase anchor protein 12 [IPR028540]", "A-kinase anchor protein 17A [IPR034355]", "A-kinase anchoring protein 95 (AKAP95) [IPR007071]", "A1 cistron-splicing factor, AAR2 [IPR007946]", "AAA ATPase, CDC48 family [IPR005938]", "ADF/Cofilin [IPR017904]", "ADP-ribosylation factor 1-5 [IPR045872]", "ADP-ribosylation factor-like protein 2 [IPR045873]", "ADP-ribosylation factor-like protein 2/3 [IPR044612]", "ADP-ribosylation factor-like protein 8A/8B [IPR044154]", "ADP-ribosylation/Crystallin J1 [IPR005502]", "ADP-specific phosphofructokinase/glucokinase [IPR007666]", "ADP/ATP carrier protein, eukaryotic type [IPR002113]", "AH receptor-interacting protein [IPR031208]", "AIP/AIPL1 [IPR039663]", "AP complex subunit beta [IPR026739]", "AP endonuclease 1 [IPR004808]", "AP-1/2/4 complex subunit beta [IPR016342]", "AP-3 complex subunit beta [IPR026740]", "ARMET-like [IPR045333]", "ATP synthase membrane subunit K [IPR009125]", "ATP synthase, F0 complex, subunit A [IPR000568]", "ATP synthase, F0 complex, subunit A, bacterial/mitochondria [IPR045083]", "ATP synthase, F0 complex, subunit B [IPR013837]", "ATP synthase, F0 complex, subunit B/MI25 [IPR008688]", "ATP synthase, F0 complex, subunit D, mitochondrial [IPR008689]", "ATP synthase, F0 complex, subunit E, mitochondrial [IPR008386]", "ATP synthase, F0 complex, subunit G, mitochondrial [IPR006808]", "ATP synthase, F1 complex, alpha subunit [IPR005294]", "ATP synthase, F1 complex, beta subunit [IPR005722]", "ATP synthase, F1 complex, gamma subunit [IPR000131]", "ATP-binding cassette sub-family C member 4 [IPR030240]", "ATP-binding cassette subfamily B member 10-like [IPR030260]", "ATP-citrate synthase [IPR014608]", "ATP-dependent 6-phosphofructokinase [IPR022953]", "ATP-dependent 6-phosphofructokinase, eukaryotic-type [IPR009161]", "ATP-dependent 6-phosphofructokinase, vertebrate-type [IPR041914]", "ATP-dependent Clp protease proteolytic subunit [IPR001907]", "ATP-dependent RNA helicase DHX29 [IPR034730]", "ATP-dependent RNA helicase Ski2-like [IPR016438]", "ATP-dependent helicase Rad3/Chl1-like [IPR013020]", "ATP11 [IPR010591]", "ATP:cob(I)alamin adenosyltransferase, PduO-type [IPR029499]", "ATP:guanido phosphotransferase [IPR000749]", "ATPase family AAA domain-containing protein 3 [IPR039188]", "ATPase, OSCP/delta subunit [IPR000711]", "ATPase, V0 complex, c/d subunit [IPR002843]", "ATPase, V0 complex, subunit 116kDa, eukaryotic [IPR026028]", "ATPase, V0 complex, subunit d [IPR016727]", "ATPase, V1 complex, subunit A [IPR005725]", "ATPase, V1 complex, subunit B [IPR005723]", "ATPase, V1 complex, subunit C [IPR004907]", "ATPase, V1 complex, subunit D [IPR002699]", "ATPase, V1 complex, subunit H [IPR004908]", "ATPase, vacuolar ER assembly factor, Vma12 [IPR021013]", "Abnormal spindle-like microcephaly-associated protein [IPR029955]", "Acid ceramidase-like [IPR016699]", "Acidic leucine-rich nuclear phosphoprotein 32 [IPR045081]", "Acireductone dioxygenase ARD family [IPR004313]", "Aconitase, mitochondrial-like [IPR006248]", "Actin family [IPR004000]", "Actin-related protein 10 [IPR027127]", "Actin-related protein 2/3 complex subunit 1 [IPR017383]", "Actin-related protein 2/3 complex subunit 1A [IPR030140]", "Actin-related protein 2/3 complex subunit 1B [IPR030141]", "Actin-related protein 2/3 complex subunit 2 [IPR007188]", "Actin-related protein 2/3 complex subunit 3 [IPR007204]", "Actin-related protein 2/3 complex subunit 4 [IPR008384]", "Actin-related protein 2/3 complex subunit 5 [IPR006789]", "Actin-related protein 3 [IPR015623]", "Activator of 90kDa heat shock protein ATPase-like [IPR039981]", "Activator of Hsp90 ATPase homologue 1-like [IPR013538]", "Active zone protein ELKS [IPR019323]", "Activity-dependent neuroprotector homeobox protein [IPR038861]", "Acyl-CoA desaturase [IPR015876]", "Acyl-CoA oxidase [IPR012258]", "Acyl-coenzyme A thioesterase 13 [IPR039298]", "Acylneuraminate cytidylyltransferase [IPR003329]", "Acyltransferase ChoActase/COT/CPT [IPR000542]", "Adaptor protein complex AP-1, gamma subunit [IPR017107]", "Adaptor protein complex AP-2, alpha subunit [IPR017104]", "Adaptor protein complex AP-3, delta subunit [IPR017105]", "Adenine phosphoribosyl transferase [IPR005764]", "Adenosine deaminase [IPR028893]", "Adenosine kinase [IPR001805]", "Adenosine/adenine deaminase [IPR006330]", "Adenosylhomocysteinase-like [IPR000043]", "Adenylate cyclase-associated CAP [IPR001837]", "Adenylate kinase 2 [IPR028587]", "Adenylate kinase 3/4, mitochondrial [IPR028586]", "Adenylate kinase 4, mitochondrial [IPR028585]", "Adenylate kinase isoenzyme 1 [IPR028582]", "Adenylate kinase isoenzyme 6 [IPR020618]", "Adenylate kinase subfamily [IPR006259]", "Adenylate kinase, isozyme 1/5 [IPR006267]", "Adenylate kinase/UMP-CMP kinase [IPR000850]", "Adenylosuccinate lyase [IPR004769]", "Adenylosuccinate synthetase [IPR001114]", "Adenylosuccinate synthetase isozyme 2, chordates [IPR027529]", "Adenylyl cyclase-associated protein CAP1 [IPR028415]", "Adenylyl-sulfate kinase [IPR002891]", "AdoMet-dependent rRNA methyltransferase Spb1-like [IPR028589]", "Aladin [IPR045139]", "Alanine-tRNA ligase, class IIc [IPR002318]", "Alanine-tRNA ligase, eukaryota/bacteria [IPR023033]", "Alcohol dehydrogenase class III [IPR014183]", "Aldehyde dehydrogenase NAD(P)-dependent [IPR012394]", "Aldehyde dehydrogenase family 7 member A1-like [IPR044638]", "Aldo-keto reductase [IPR020471]", "Aldo-keto reductase family 1 member A1 [IPR044481]", "Aldose 1-/Glucose-6-phosphate 1-epimerase [IPR008183]", "Aldose 1-epimerase [IPR015443]", "Alkyldihydroxyacetonephosphate synthase [IPR025650]", "Alpha E-catenin/Alpha T-catenin [IPR030047]", "Alpha crystallin/Small heat shock protein, animal type [IPR001436]", "Alpha-2-macroglobulin receptor-associated protein [IPR038003]", "Alpha-D-phosphohexomutase superfamily [IPR005841]", "Alpha-L-fucosidase, metazoa-type [IPR016286]", "Alpha-N-acetylglucosaminidase [IPR007781]", "Alpha-N-methyltransferase NTM1 [IPR008576]", "Alpha-adducin [IPR027766]", "Alpha-catenin [IPR001033]", "Alpha-internexin [IPR027703]", "Alpha-ketoglutarate-dependent dioxygenase FTO [IPR032868]", "Amidase [IPR000120]", "Amidophosphoribosyltransferase [IPR005854]", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 [IPR042360]", "Aminoacyl-tRNA synthetase, class Ic [IPR002305]", "Aminopeptidase N-type [IPR034016]", "Aminopeptidase, leukotriene A4 hydrolase-like [IPR034015]", "Aminotransferase ALAT1/2-like [IPR045088]", "Aminotransferase class IV [IPR001544]", "Aminotransferase class-III [IPR005814]", "Anamorsin [IPR007785]", "Anaphase-promoting complex subunit 16 [IPR029641]", "Anaphase-promoting complex subunit 5 [IPR037679]", "Ancient conserved domain protein family [IPR045095]", "Angiomotin [IPR009114]", "Ankycorbin [IPR042420]", "Ankyrin repeat and LEM domain-containing protein 2 [IPR035007]", "Annexin A1 [IPR002388]", "Annexin A11 [IPR008157]", "Annexin A2 [IPR002389]", "Annexin A4 [IPR002391]", "Annexin A6 [IPR002393]", "Annexin [IPR001464]", "Antifreeze, type III [IPR006013]", "Apolipoprotein L [IPR008405]", "Apoptosis inhibitory 5 [IPR008383]", "Apoptosis regulator BAK [IPR026308]", "Apoptosis regulator BAX [IPR026304]", "ArfGAP ACAP1/2/3-like [IPR045258]", "Arfaptin family [IPR030798]", "Arfaptin-1 [IPR030793]", "Arginine-tRNA ligase [IPR001278]", "Armadillo repeat-containing protein 6 [IPR040104]", "Arsenical pump ATPase, ArsA/GET3 [IPR016300]", "Arsenical pump ATPase, ArsA/GET3, eukaryotic [IPR027542]", "Arsenite methyltransferase-like [IPR026669]", "Arylesterase [IPR002640]", "Ashwin [IPR024887]", "Asparaginase-like 1, metazoa [IPR033844]", "Asparagine synthase, glutamine-hydrolyzing [IPR006426]", "Asparagine-tRNA ligase [IPR004522]", "Aspartate carbamoyltransferase [IPR002082]", "Aspartate-tRNA ligase, type 1 [IPR004524]", "Aspartate-tRNA synthetase, type 2 [IPR004523]", "Aspartate/ornithine carbamoyltransferase [IPR006130]", "Aspartate/other aminotransferase [IPR000796]", "Aspartyl/Asparaginyl-tRNA synthetase, class IIb [IPR002312]", "Aspartyl/asparaginyl beta-hydroxylase family [IPR039038]", "Ataxin2-like [IPR045117]", "Atypical dual specificity phosphatase, subfamily A [IPR020405]", "Autophagy protein Atg8 ubiquitin-like [IPR004241]", "B-cell lymphoma/leukemia 10/E10 [IPR033238]", "B-cell receptor-associated protein 29/31 [IPR008417]", "BAG family molecular chaperone regulator 2 [IPR037689]", "BBP/SF1 family [IPR031150]", "BCP1 family [IPR025602]", "BET1-like protein [IPR039897]", "BLOC-2 complex, Hps6 subunit [IPR017218]", "BRCA1-A complex subunit BRE [IPR010358]", "BRI3-binding protein [IPR033367]", "BRISC and BRCA1-A complex member 1 [IPR026126]", "Bacterial/eukaryotic lysine-tRNA ligase, class II [IPR034762]", "Baculoviral IAP repeat-containing protein 6 [IPR022103]", "Band 4.1 protein, chordates [IPR021187]", "Band 4.1-like protein 2 [IPR030546]", "Band 4.1-like protein 3 [IPR030691]", "Barrier- to-autointegration factor, BAF [IPR004122]", "Basigin [IPR044157]", "Basigin-like [IPR043204]", "Bax inhibitor 1-related [IPR006214]", "Bcl-2 family [IPR026298]", "Bcl-2-associated transcription factor 1 [IPR026668]", "Bcl-2-like protein 13 [IPR042398]", "Bcl2-like [IPR002475]", "Beta tubulin [IPR002453]", "Beta-1,4-glucuronyltransferase 1 [IPR043189]", "Beta-N-acetylglucosaminidase [IPR011496]", "Beta-catenin [IPR013284]", "Beta-catenin-like protein 1 [IPR039678]", "Beta-galactosidase 1-like [IPR026283]", "Beta-hexosaminidase [IPR025705]", "Beta-lactamase HcpB-like [IPR040239]", "Bifunctional purine biosynthesis protein PurH-like [IPR002695]", "Biliverdin reductase A [IPR017094]", "Biotin--acetyl-CoA-carboxylase ligase [IPR004408]", "Brain acid soluble protein 1 [IPR008408]", "Branched-chain amino acid aminotransferase II [IPR005786]", "Branched-chain aminotransferase [IPR033939]", "Bystin [IPR007955]", "C-5 cytosine methyltransferase [IPR001525]", "C-terminal binding protein [IPR043322]", "C2 domain-containing protein 2-like [IPR039934]", "C2 domain-containing protein 5 [IPR038983]", "CAAX prenyl protease 1 [IPR027057]", "CCR4-NOT transcription complex subunit 1 [IPR040398]", "CCR4-NOT transcription complex subunit 11 [IPR019312]", "CCR4-NOT transcription complex subunit 7 [IPR039636]", "CCR4-NOT transcription complex subunit 7/8/Pop2 [IPR039637]", "CCR4-NOT transcription complex subunit 9 [IPR007216]", "CD2 antigen cytoplasmic tail-binding protein 2/Lin1 [IPR039905]", "CD2-associated protein [IPR028445]", "CD36 family [IPR002159]", "CD36/scavenger receptor class B member 1 [IPR005428]", "CDC45 family [IPR003874]", "CDGSH iron-sulfur domain-containing protein 1/2 [IPR045131]", "CDK2-associated and cullin domain-containing protein 1 [IPR042652]", "CDK5 regulatory subunit-associated protein 3 [IPR008491]", "CEBPZ/Mak21-like [IPR040155]", "CGG triplet repeat-binding protein 1 [IPR033375]", "CHORD domain containing protein [IPR039790]", "CLU domain containing protein [IPR027523]", "COMM domain-containing protein 10 [IPR037361]", "COMM domain-containing protein 2 [IPR037354]", "COMPASS component Swd2/WDR82 [IPR037867]", "COP9 signalosome complex subunit 1 [IPR033008]", "COP9 signalosome complex subunit 2 [IPR037750]", "COP9 signalosome complex subunit 3 [IPR037753]", "COP9 signalosome complex subunit 4 [IPR037754]", "COP9 signalosome complex subunit 5 [IPR037740]", "COP9 signalosome subunit 6 [IPR033859]", "COP9 signalosome, subunit CSN8 [IPR033205]", "COPII coat assembly protein, Sec16 [IPR024880]", "CPSF6/7 family [IPR034772]", "CTP synthase [IPR004468]", "CWF11 family [IPR026300]", "CXXC motif containing zinc binding protein, eukaryotic [IPR008584]", "CYFIP-related Rac1 interactor [IPR039789]", "Calcium homeostasis endoplasmic reticulum protein [IPR039037]", "Calcium load-activated calcium channel [IPR008559]", "Calcium uptake protein 1/2/3 [IPR039800]", "Calcium-binding mitochondrial carrier protein Aralar2 [IPR029658]", "Calcium-transporting ATPase type 2C member 1 [IPR030336]", "Caldesmon [IPR006017]", "Caldesmon/lymphocyte specific protein [IPR006018]", "Calpain-1 [IPR029643]", "Calpastatin [IPR026998]", "Calponin-2 [IPR029974]", "Calponin/LIMCH1 [IPR001997]", "Calreticulin [IPR009169]", "Calreticulin/calnexin [IPR001580]", "Calumenin [IPR027239]", "Cap-specific mRNA (nucleoside-2-O-)-methyltransferase 1 [IPR030376]", "Caprin [IPR028816]", "Carbamoyl-phosphate synthase, large subunit [IPR006275]", "Carbamoyl-phosphate synthase, small subunit [IPR006274]", "Carbohydrate sulfotransferase 8-10 [IPR018011]", "Cartilage-associated protein [IPR033212]", "Casein Kinase 2, subunit alpha [IPR045216]", "Casein kinase II, regulatory subunit [IPR000704]", "Caspase-2 [IPR035702]", "Caspase-3/7 [IPR015471]", "Caspase-6 [IPR037554]", "Cat eye syndrome critical region protein 5 [IPR029621]", "Catechol O-methyltransferase, eukaryotic [IPR017128]", "Catenin delta-1 [IPR028439]", "Cation efflux protein [IPR002524]", "Cation-dependent mannose-6-phosphate receptor [IPR000296]", "Cdc37 [IPR004918]", "Cdc42 [IPR037874]", "Cdc73/Parafibromin [IPR007852]", "Cell cycle and apoptosis regulator protein 2 [IPR028811]", "Cell cycle and apoptosis regulator protein [IPR025224]", "Cell division cycle protein 123 [IPR009772]", "Cell division protein borealin [IPR018867]", "Cell growth-regulating nucleolar protein [IPR039999]", "Cell-cycle alteration and expression-elevated protein in tumour [IPR032337]", "Centrosomal protein of 170kDa [IPR026644]", "Centrosomal protein of 44kDa [IPR033603]", "Centrosomal protein of 55kDa [IPR038926]", "Ceroid-lipofuscinosis neuronal protein 5 [IPR026138]", "Cgr1-like [IPR005579]", "Chaperone DnaJ [IPR012724]", "Chaperone DnaK [IPR012725]", "Chaperone tailless complex polypeptide 1 (TCP-1) [IPR017998]", "Chaperonin Cpn60/GroEL [IPR001844]", "Chaperonin Cpn60/GroEL/TCP-1 family [IPR002423]", "Chitobiosyldiphosphodolichol beta-mannosyltransferase ALG1-like [IPR026051]", "Chloride channel ClC-3 [IPR002245]", "Chloride channel ClC-7 [IPR002249]", "Chloride channel, voltage gated [IPR001807]", "Chloride intracellular channel protein 1 [IPR030259]", "Chloride intracellular channel protein 4/6 [IPR030257]", "Chromatid cohesion factor MAU2 [IPR019440]", "Chromatin assembly factor 1 subunit A [IPR022043]", "Chromatin assembly factor 1 subunit Cac2/CHAF1B/FAS2 [IPR045145]", "Chromatin complexes subunit BAP18 [IPR037931]", "Chromatin-remodeling complex component Sfh1/SNF5 [IPR017393]", "Chromobox protein homologue 3 [IPR038033]", "Chromodomain-helicase-DNA-binding protein 1-like [IPR031053]", "Chromosome alignment-maintaining phosphoprotein 1 [IPR039330]", "Cilia- and flagella-associated protein 20/CFAP20DC [IPR040441]", "Cilia- and flagella-associated protein 298 [IPR021298]", "Cip1-interacting zinc finger protein [IPR026811]", "Citrate synthase [IPR002020]", "Citrate synthase, eukaryotic-type [IPR010109]", "Claspin [IPR024146]", "Class I-like SAM-dependent O-methyltransferase [IPR002935]", "Clathrin adaptor, mu subunit [IPR001392]", "Clathrin coat assembly protein AP180-like [IPR045192]", "Clathrin interactor 1 [IPR030544]", "Clathrin light chain [IPR000996]", "Clathrin, heavy chain [IPR016341]", "Cleavage and polyadenylation specificity factor subunit 2 [IPR027075]", "Cleavage and polyadenylation specificity factor subunit 6 [IPR034769]", "Cleavage and polyadenylation specificity factor subunit 7 [IPR034770]", "Cleavage stimulation factor subunit 1-like [IPR044633]", "Cleavage stimulation factor subunit 2 [IPR033105]", "Cleavage/polyadenylation specificity factor subunit 5 [IPR016706]", "Cleft lip and palate transmembrane 1 [IPR008429]", "Cleft lip and palate transmembrane protein 1-like protein [IPR030434]", "Clp protease proteolytic subunit /Translocation-enhancing protein TepA [IPR023562]", "Clp protease, ATP-binding subunit ClpX [IPR004487]", "ClpA/B family [IPR001270]", "Co-chaperone protein p23-like [IPR045250]", "Coactosin-like protein [IPR030502]", "Coatomer alpha subunit [IPR016391]", "Coatomer beta subunit (COPB1) [IPR016460]", "Coatomer beta' subunit (COPB2) [IPR016453]", "Coatomer delta subunit [IPR027059]", "Coatomer gamma subunit [IPR017106]", "Coatomer subunit zeta [IPR039652]", "Coatomer, epsilon subunit [IPR006822]", "Cofactor of BRCA1 [IPR010405]", "Cofilin 1 [IPR027234]", "Cohesin subunit Scc3/SA [IPR039662]", "Coiled-coil domain-containing protein 124/Oxs1 [IPR010422]", "Coiled-coil domain-containing protein 86 [IPR026570]", "Coilin [IPR024822]", "Condensin complex subunit 2/barren [IPR022816]", "Condensin complex subunit 3 [IPR027165]", "Condensin subunit 1 [IPR007673]", "Condensin subunit 1/Condensin-2 complex subunit D3 [IPR026971]", "Condensin-2 complex subunit D3 [IPR012371]", "Condensin-2 complex subunit H2 [IPR031739]", "Conserved oligomeric Golgi complex subunit 7 [IPR019335]", "Constitutive coactivator of PPAR-gamma [IPR026784]", "Copine [IPR045052]", "Copper chaperone SCO1/SenC [IPR003782]", "Coproporphyrinogen III oxidase, aerobic [IPR001260]", "Core histone macro-H2A [IPR021171]", "Core-binding factor, beta subunit [IPR003417]", "Coronin 1C [IPR027333]", "Coronin [IPR015505]", "Cortactin [IPR015503]", "Cullin [IPR045093]", "Cullin-4B [IPR033044]", "Cullin-associated NEDD8-dissociated protein 1/2 [IPR039852]", "Cwf19-like protein [IPR040194]", "Cyclic nucleotide phosphodiesterase [IPR008431]", "Cyclin [IPR039361]", "Cyclin-dependent kinase 6 [IPR028788]", "Cyclophilin-RNA interacting protein [IPR035542]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase [IPR024936]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, cyclophilin A-like [IPR044666]", "Cysteine desulfurase IscS [IPR010240]", "Cysteine desulfurase [IPR016454]", "Cysteine oxygenase/2-aminoethanethiol dioxygenase [IPR012864]", "Cysteine protease ATG4B, metazoa [IPR032916]", "Cysteine-tRNA ligase [IPR015803]", "Cysteinyl-tRNA synthetase/mycothiol ligase [IPR024909]", "Cystinyl aminopeptidase [IPR034017]", "Cytochrome B561-related [IPR019176]", "Cytochrome P450 [IPR001128]", "Cytochrome P450, E-class, group I [IPR002401]", "Cytochrome P450, E-class, group IV [IPR002403]", "Cytochrome b-c1 complex subunit 7 [IPR003197]", "Cytochrome b-c1 complex subunit 8 [IPR004205]", "Cytochrome b-c1 complex subunit 9 [IPR008027]", "Cytochrome c oxidase assembly factor 3, mitochondrial [IPR041752]", "Cytochrome c oxidase subunit 6C [IPR004204]", "Cytochrome c oxidase subunit IV [IPR013288]", "Cytochrome c oxidase subunit IV family [IPR004203]", "Cytochrome c oxidase subunit VII [IPR039297]", "Cytochrome c oxidase subunit VIIa, metazoa [IPR003177]", "Cytochrome c oxidase subunit VIIc [IPR004202]", "Cytochrome c oxidase, subunit Va/VI [IPR003204]", "Cytochrome c oxidase, subunit Vb [IPR002124]", "Cytochrome c/quinol oxidase subunit II [IPR045187]", "Cytochrome c1 [IPR002326]", "Cytoplasmic FMR1-interacting [IPR008081]", "Cytoplasmic dynein 1 intermediate chain 1/2 [IPR025956]", "Cytoplasmic protein NCK [IPR017304]", "Cytoplasmic protein NCK1 [IPR028526]", "Cytoskeleton-associated protein 2 family [IPR026165]", "Cytoskeleton-associated protein 4 [IPR028428]", "Cytosolic Fe-S cluster assembly factor NUBP2/Cfd1, eukaryotes [IPR028600]", "Cytosolic acyl coenzyme A thioester hydrolase [IPR040170]", "Cytosolic nonspecific dipeptidase/DUG1 [IPR017153]", "Cytospin-A [IPR040166]", "D-3-phosphoglycerate dehydrogenase [IPR006236]", "DAD/Ost2 [IPR003038]", "DDRGK domain containing protein [IPR019153]", "DDX54/DBP10 family [IPR033517]", "DENR family, eukaryotes [IPR005873]", "DET1- and DDB1-associated protein 1 [IPR033575]", "DIS3-like exonuclease 2 [IPR028591]", "DNA (cytosine-5)-methyltransferase 1-like [IPR017198]", "DNA damage-binding protein 1 [IPR031297]", "DNA double-strand break repair protein Mre11 [IPR003701]", "DNA fragmentation factor 45 [IPR017299]", "DNA helicase, ATP-dependent, RecQ type [IPR004589]", "DNA ligase, ATP-dependent [IPR000977]", "DNA mismatch repair Msh2-type [IPR011184]", "DNA mismatch repair MutS family [IPR045076]", "DNA mismatch repair protein Msh2 [IPR032642]", "DNA mismatch repair protein MutS/MSH [IPR017261]", "DNA polymerase V/Myb-binding protein 1A [IPR007015]", "DNA polymerase alpha, subunit B [IPR016722]", "DNA polymerase epsilon catalytic subunit [IPR029703]", "DNA primase large subunit, eukaryotic/archaeal [IPR007238]", "DNA primase, large subunit, eukaryotic [IPR016558]", "DNA primase, small subunit [IPR002755]", "DNA primase, small subunit, eukaryotic/archaeal [IPR014052]", "DNA repair protein Rad50, eukaryotes [IPR004584]", "DNA repair/transcription protein MET18/MMS19 [IPR039920]", "DNA replication complex GINS protein Psf2 [IPR007257]", "DNA replication licensing factor Mcm2 [IPR008045]", "DNA replication licensing factor Mcm3 [IPR008046]", "DNA replication licensing factor Mcm5 [IPR008048]", "DNA replication licensing factor Mcm6 [IPR008049]", "DNA replication licensing factor Mcm7 [IPR008050]", "DNA replication/checkpoint protein [IPR021110]", "DNA topoisomerase I [IPR001631]", "DNA topoisomerase II, eukaryotic-type [IPR001154]", "DNA topoisomerase II-beta [IPR028467]", "DNA topoisomerase, type IIA [IPR001241]", "DNA-directed DNA polymerase, family B [IPR006172]", "DNA-directed RNA pol I, largest subunit [IPR015699]", "DNA-directed RNA polymerase subunit RPABC5/Rpb10 [IPR000268]", "DNA-directed RNA polymerase subunit Rpo5/Rpb5 [IPR014381]", "DNA-directed RNA polymerase, phage-type [IPR002092]", "DNA-directed RNA polymerase, subunit 2 [IPR015712]", "DNA-directed RNA polymerase, subunit beta-prime [IPR045867]", "DNA-directed RNA polymerases I and III subunit AC40 [IPR033901]", "DNA2/NAM7-like helicase [IPR045055]", "DPM1-like [IPR039528]", "Daxx protein [IPR005012]", "Death-inducer obliterator 1 [IPR033082]", "Delta l-pyrroline-5-carboxylate synthetase [IPR005766]", "Delta(24)-sterol reductase [IPR040165]", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase Ech1-like [IPR045002]", "Delta-1-pyrroline-5-carboxylate dehydrogenase [IPR005931]", "Deoxyhypusine hydroxylase [IPR027517]", "Deoxyhypusine synthase [IPR002773]", "Deoxyuridine triphosphate nucleotidohydrolase [IPR008181]", "Dephospho-CoA kinase [IPR001977]", "Derlin [IPR007599]", "Dermcidin [IPR028130]", "Dermcidin/Lacritin [IPR043557]", "Desmoglein [IPR009123]", "Desmoplakin [IPR028462]", "Desmosomal cadherin [IPR009122]", "Destrin [IPR029924]", "Deubiquitinating enzyme MINDY-3/4 [IPR039785]", "Developmentally regulated GTP-binding protein [IPR045001]", "Dihydrofolate reductase [IPR012259]", "Dihydrolipoamide acetyltransferase/Pyruvate dehydrogenase protein X component [IPR045257]", "Dihydrolipoamide dehydrogenase [IPR006258]", "Dihydrolipoamide succinyltransferase [IPR006255]", "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex [IPR006257]", "Dihydropyrimidinase-related protein 2 [IPR030615]", "Dihydropyrimidinase-related protein 3 [IPR030628]", "Dipeptidyl-peptidase 3 [IPR005317]", "Diphosphomevalonate decarboxylase [IPR029765]", "Diphosphomevalonate/phosphomevalonate decarboxylase [IPR005935]", "Diphthamide synthesis DHP2 [IPR010014]", "Diphthamide synthesis DPH1/DPH2 [IPR016435]", "Divalent ion tolerance protein, CutA [IPR004323]", "DnaJ homolog subfamily A member 1/2-like [IPR044713]", "DnaJ homolog subfamily C member 8 [IPR042858]", "DnaJ homologue subfamily C member 10 [IPR021170]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48kDa subunit [IPR005013]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit Swp1 [IPR008814]", "Drebrin [IPR028438]", "Drebrin-like protein [IPR029923]", "Dual specificity protein phosphatase 12 [IPR016278]", "Dynactin subunit 3 [IPR009991]", "Dynactin subunit 4 [IPR008603]", "Dynamin [IPR022812]", "Dynamin-1 [IPR027741]", "Dynamin-1-like protein [IPR030556]", "Dynamin-2 [IPR027188]", "Dynamin-like 120kDa protein, mitochondrial [IPR033047]", "Dynamitin [IPR028133]", "Dynein 1 light intermediate chain [IPR008467]", "Dynein family light intermediate chain [IPR022780]", "Dynein light chain, type 1/2 [IPR001372]", "Dynein regulator LIS1 [IPR017252]", "Dystrophin/utrophin [IPR035436]", "E3 SUMO-protein ligase Nse2 (Mms21) [IPR026846]", "E3 UFM1-protein ligase 1 [IPR018611]", "E3 ubiquitin ligase Bre1 [IPR013956]", "E3 ubiquitin ligase RBR family [IPR031127]", "E3 ubiquitin ligase UBR4-like [IPR045189]", "E3 ubiquitin-protein ligase CHIP/LubX [IPR045200]", "E3 ubiquitin-protein ligase HECTD1/TRIP12-like [IPR045322]", "E3 ubiquitin-protein ligase RBBP6 family [IPR033489]", "E3 ubiquitin-protein ligase RNF14 [IPR031128]", "E3 ubiquitin-protein ligase ZNF598/Hel2 [IPR044288]", "E3 ubiquitin-protein ligase listerin [IPR039795]", "E3 ubiquitin-protein ligase, SMURF1 type [IPR024928]", "EB1, Metazoa [IPR027739]", "EB2, vertebrate [IPR027735]", "ECSIT [IPR010418]", "EF-hand calcium-binding domain-containing protein 14 [IPR042352]", "EH domain-containing protein 1/3 [IPR029951]", "ELMO domain-containing protein 2 [IPR030724]", "ELP3/YhcC [IPR039661]", "ER lumen protein retaining receptor [IPR000133]", "ER membrane protein complex subunit 1 [IPR026895]", "ER membrane protein complex subunit 2-like [IPR039856]", "ER membrane protein complex subunit 7 [IPR039163]", "ER membrane protein complex subunit 8/9 [IPR005366]", "ERAP2 aminopeptidase [IPR033528]", "ERG2/sigma1 receptor-like [IPR006716]", "ERp19 [IPR037462]", "Ecd family [IPR010770]", "Electron transfer flavoprotein alpha subunit/FixB [IPR001308]", "Electron transfer flavoprotein, beta subunit [IPR012255]", "Electron transfer flavoprotein-ubiquinone oxidoreductase [IPR040156]", "Elongation factor G1-like [IPR045044]", "Elongator complex protein 1 [IPR006849]", "Elongator complex protein 2 [IPR037289]", "Elongator complex protein 3-like [IPR034687]", "Elongator complex protein 4 [IPR008728]", "Elongin B [IPR039049]", "Elongin-C [IPR039948]", "Emerin [IPR035004]", "Emopamil-binding protein [IPR007905]", "Endonuclease domain-containing 1 protein [IPR039015]", "Endophilin-A [IPR028501]", "Endophilin-B1 [IPR028503]", "Endoplasmic reticulum aninopeptidase 1 [IPR033520]", "Endoplasmic reticulum oxidoreductin 1 [IPR007266]", "Endoplasmic reticulum resident protein 29 [IPR016855]", "Endoplasmic reticulum vesicle transporter [IPR045888]", "Endosulphine [IPR006760]", "Endothelin-converting enzyme 1 [IPR029734]", "Engulfment and cell motility protein 2 [IPR030713]", "Enhancer of mRNA-decapping protein 4-like [IPR045152]", "Enhancer of rudimentary [IPR000781]", "Enolase [IPR000941]", "Enolase-phosphatase E1 [IPR023943]", "Enolase-phosphatase E1, eukaryotes [IPR027511]", "Enoyl-CoA hydratase/isomerase [IPR001753]", "Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type [IPR032259]", "Epimerase family protein SDR39U1 [IPR010099]", "Epoxide hydrolase [IPR016292]", "Epoxide hydrolase-like [IPR000639]", "Equilibrative nucleoside transporter 1 [IPR030195]", "Equilibrative nucleoside transporter [IPR002259]", "Ergosterol biosynthesis ERG4/ERG24 [IPR001171]", "Erlin1/2 [IPR033294]", "Esterase-like [IPR000801]", "Etoposide-induced 2.4 [IPR009890]", "Eukaryotic porin/Tom40 [IPR027246]", "Eukaryotic rRNA processing [IPR008610]", "Eukaryotic translation elongation factor 1 epsilon-1 [IPR042450]", "Eukaryotic translation initiation factor 2D [IPR039757]", "Eukaryotic translation initiation factor 3 subunit A [IPR027512]", "Eukaryotic translation initiation factor 3 subunit B [IPR011400]", "Eukaryotic translation initiation factor 3 subunit D [IPR007783]", "Eukaryotic translation initiation factor 3 subunit E [IPR016650]", "Eukaryotic translation initiation factor 3 subunit F [IPR027531]", "Eukaryotic translation initiation factor 3 subunit G [IPR017334]", "Eukaryotic translation initiation factor 3 subunit H [IPR027524]", "Eukaryotic translation initiation factor 3 subunit I [IPR027525]", "Eukaryotic translation initiation factor 3 subunit J [IPR013906]", "Eukaryotic translation initiation factor 3 subunit K [IPR009374]", "Eukaryotic translation initiation factor 3 subunit M [IPR027528]", "Eukaryotic translation initiation factor 3 subunit M eIF3m/COP9 signalosome complex subunit 7 COPS7 [IPR045237]", "Eukaryotic translation initiation factor 4 gamma 1 [IPR037584]", "Eukaryotic translation initiation factor 4 gamma 3 [IPR037585]", "Eukaryotic translation initiation factor 4B [IPR033107]", "Exocyst complex component EXOC2/Sec5 [IPR029175]", "Exocyst complex component EXOC5/Sec10 [IPR033960]", "Exocyst complex component EXOC6/Sec15 [IPR007225]", "Exocyst complex component Exo70 [IPR004140]", "Exocyst complex component Sec10-like [IPR009976]", "Exocyst complex component Sec8/EXOC4 [IPR039682]", "Exonuclease 1 [IPR032641]", "Exosome complex RNA-binding protein 1/RRP40/RRP4 [IPR026699]", "Exosome complex component RRP45 [IPR033100]", "Exosome complex component Rrp43 [IPR033196]", "Exosome complex exonuclease Rrp6-like [IPR045092]", "Exportin 4/7-like [IPR044189]", "Exportin-1/5 [IPR045065]", "Exportin-5 [IPR040018]", "Exportin-7 [IPR040021]", "Exportin-T [IPR040017]", "Eyes absent family [IPR028472]", "Eyes absent homologue 3 [IPR028479]", "Ezrin/radixin/moesin [IPR011174]", "Ezrin/radixin/moesin-like [IPR000798]", "F-actin-capping protein subunit alpha [IPR002189]", "F-actin-capping protein subunit beta [IPR001698]", "FACT complex subunit Spt16 [IPR040258]", "FAD-dependent glycerol-3-phosphate dehydrogenase [IPR000447]", "FAD-dependent oxidoreductase SdhA/FrdA/AprA [IPR030664]", "FAM105 [IPR023235]", "FAM175 family [IPR023238]", "FAM175 family, BRISC complex, Abro1 subunit [IPR023240]", "FAM177 family [IPR028260]", "FAM3 family [IPR039220]", "FAM91 [IPR039199]", "FAM98 [IPR018797]", "FH1/FH2 domain-containing protein 1 [IPR027647]", "FUN14 [IPR007014]", "Family of unknown function DUF5525 [IPR037656]", "Fanconi anaemia protein FANCD2 [IPR029448]", "Fanconi anemia group I protein [IPR026171]", "Fascin [IPR010431]", "Fascin, metazoans [IPR024703]", "Fascin-1 [IPR030146]", "Fatty acid desaturase [IPR012171]", "Fatty acid oxidation complex, alpha subunit, mitochondrial [IPR012803]", "Fatty acid transport protein 4 [IPR030304]", "Fatty acyl-CoA reductase [IPR026055]", "Fcf2/DNTTIP2 [IPR039883]", "Ferredoxin-NADP+ reductase, adrenodoxin-type [IPR021163]", "Ferrochelatase [IPR001015]", "Fibrillarin [IPR000692]", "Filamin family [IPR044801]", "Filamin-B [IPR029874]", "Fimbrin/Plastin [IPR039959]", "Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 [IPR033756]", "Flap endonuclease 1 [IPR023426]", "Flotillin family [IPR027705]", "Folliculin [IPR021713]", "Forkhead box protein C1 [IPR033067]", "Formate-tetrahydrofolate ligase, FTHFS [IPR000559]", "Formin, protein diaphanous homologue 1 [IPR027653]", "Formin, protein diaphanous homologue 3 [IPR027654]", "Four and a half LIM domains protein 1 [IPR042997]", "Fragile X mental retardation syndrome-related protein [IPR040148]", "Fructosamine/Ketosamine-3-kinase [IPR016477]", "Fructose-bisphosphate aldolase, class-I [IPR000741]", "Fumarate hydratase, class II [IPR005677]", "Fumarate lyase family [IPR000362]", "Fumarylacetoacetase [IPR005959]", "G-protein alpha subunit, group 12/13 [IPR000469]", "G-protein alpha subunit, group I [IPR001408]", "G-protein, gamma subunit [IPR001770]", "G-rich sequence factor 1 [IPR033106]", "G10 protein [IPR001748]", "GDP dissociation inhibitor [IPR018203]", "GDP-L-fucose synthase/GDP-L-colitose synthase [IPR028614]", "GDP-fucose protein O-fucosyltransferase 1 [IPR039922]", "GDP-fucose protein O-fucosyltransferase [IPR019378]", "GINS complex subunit Sld5 [IPR008591]", "GINS complex, subunit Psf1 [IPR005339]", "GINS complex, subunit Psf3 [IPR010492]", "GPI transamidase component Gaa1 [IPR007246]", "GPI transamidase subunit PIG-U [IPR009600]", "GPI-anchor transamidase [IPR028361]", "GRIM-19 [IPR009346]", "GRIP1-associated protein 1 [IPR026204]", "GTP-binding protein 1 [IPR039263]", "GTP-binding protein Era [IPR005662]", "GTP-binding protein Obg/CgtA [IPR014100]", "Galactokinase [IPR000705]", "Galectin-3 [IPR015534]", "Galectin-like [IPR044156]", "Gamma-glutamylcyclotransferase [IPR017939]", "Gamma-tubulin complex component protein [IPR007259]", "Ganglioside GM2 activator [IPR028996]", "Gem-associated protein 4 [IPR033265]", "Geranylgeranyl transferase type-2 subunit alpha [IPR032955]", "Glia maturation factor [IPR011171]", "Glomulin/ALF4 [IPR019516]", "Glucosamine-6-phosphate isomerase [IPR004547]", "Glucosamine-fructose-6-phosphate aminotransferase, isomerising [IPR005855]", "Glucose-6-phosphate dehydrogenase [IPR001282]", "Glucosidase II beta subunit-like [IPR039794]", "Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase [IPR005715]", "Glutamate carboxypeptidase 2-like [IPR039373]", "Glutamate--cysteine ligase regulatory subunit [IPR032963]", "Glutamate-tRNA ligase, bacterial/mitochondrial [IPR004527]", "Glutamate/acetylglutamate kinase [IPR001057]", "Glutamate/phenylalanine/leucine/valine dehydrogenase [IPR006095]", "Glutaminase [IPR015868]", "Glutamine-tRNA synthetase [IPR004514]", "Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic [IPR004526]", "Glutamyl-tRNA(Gln) amidotransferase A subunit [IPR004412]", "Glutamyl/glutaminyl-tRNA synthetase [IPR000924]", "Glutathione S-transferase Omega/Tau-like [IPR045073]", "Glutathione S-transferase kappa [IPR044088]", "Glutathione S-transferase, Mu class [IPR003081]", "Glutathione S-transferase, omega-class [IPR005442]", "Glutathione S-transferases, class Zeta [IPR005955]", "Glutathione Transferase family [IPR040079]", "Glutathione reductase, eukaryote/bacterial [IPR006322]", "Glutathione synthase [IPR005615]", "Glutathione-specific gamma-glutamylcyclotransferase [IPR006840]", "Glyceraldehyde-3-phosphate dehydrogenase, type I [IPR006424]", "Glyceraldehyde/Erythrose phosphate dehydrogenase family [IPR020831]", "Glycine cleavage system P protein [IPR020581]", "Glycine dehydrogenase (decarboxylating) [IPR003437]", "Glycogen debranching enzyme [IPR010401]", "Glycogen debranching enzyme, metazoa [IPR006421]", "Glycogen synthase [IPR008631]", "Glycogen/starch/alpha-glucan phosphorylase [IPR011833]", "Glycoside hydrolase family 30 [IPR001139]", "Glycoside hydrolase family 31 [IPR000322]", "Glycoside hydrolase family 63 [IPR004888]", "Glycoside hydrolase, family 2 [IPR006101]", "Glycoside hydrolase, family 27 [IPR002241]", "Glycoside hydrolase, family 29 [IPR000933]", "Glycoside hydrolase, family 35 [IPR001944]", "Glycosyl transferase, family 25 [IPR002654]", "Glycosyl transferase, family 35 [IPR000811]", "Glycosyl transferase, family 8 [IPR002495]", "Glycyl-tRNA synthetase [IPR002315]", "Glycyl-tRNA synthetase/DNA polymerase subunit gamma-2 [IPR027031]", "Glyoxalase I [IPR004361]", "Glyoxalase domain-containing protein 4 [IPR043193]", "Golgi apparatus protein 1 [IPR039728]", "Golgi integral membrane protein 4 [IPR042336]", "Golgi to ER traffic protein 4 [IPR007317]", "Golgi-associated PDZ and coiled-coil motif-containing protein [IPR038879]", "Golgin subfamily A member 3 [IPR033288]", "Golgin subfamily B member 1 [IPR026202]", "Graves disease carrier protein [IPR002167]", "GroES chaperonin family [IPR020818]", "Growth arrest/ DNA-damage-inducible protein-interacting protein 1 [IPR018472]", "GrpE nucleotide exchange factor [IPR000740]", "Guanine nucleotide binding protein (G-protein), alpha subunit [IPR001019]", "Guanine nucleotide-exchange factor Sec12-like [IPR045260]", "H/ACA ribonucleoprotein complex, subunit Gar1/Naf1 [IPR007504]", "H/ACA ribonucleoprotein complex, subunit Nhp2, eukaryote [IPR002415]", "HAD hydrolase, LHPP/HDHD2 [IPR006355]", "HAD hydrolase, subfamily IA [IPR006439]", "HAD-superfamily hydrolase, subfamily IA, REG-2-like [IPR011949]", "HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase [IPR008380]", "HAD-superfamily hydrolase, subfamily IIA [IPR006357]", "HAD-superfamily hydrolase, subfamily IIA, CECR5 [IPR006353]", "HAUS augmin-like complex subunit 4 [IPR029327]", "HAUS augmin-like complex subunit 4, metazoa [IPR026214]", "HAUS augmin-like complex subunit 5 [IPR029131]", "HAUS complex subunit 5, metazoa [IPR026215]", "HCCA isomerase/glutathione S-transferase kappa [IPR014440]", "HCLS1-binding protein 3 [IPR039701]", "HMG-CoA lyase [IPR043594]", "Haem oxygenase [IPR002051]", "Haem oxygenase-like [IPR016053]", "Haloacid dehalogenase-like hydrolase [IPR041492]", "Ham1-like protein [IPR002637]", "Heat shock protein 70 family [IPR013126]", "Heat shock protein Hsp90 family [IPR001404]", "Heat shock protein Sti1-like [IPR045248]", "Helicase MOV-10 [IPR026122]", "Helicase superfamily 1/2, DinG/Rad3-like [IPR045028]", "Heterochromatin protein 1-binding protein 3 [IPR033061]", "Heterogeneous nuclear ribonucleoprotein C [IPR017347]", "Heterogeneous nuclear ribonucleoprotein K [IPR033090]", "Heterogeneous nuclear ribonucleoprotein M [IPR024667]", "Heterogeneous nuclear ribonucleoprotein U [IPR026745]", "Heterogeneous nuclear ribonucleoprotein U-like protein 1 [IPR027025]", "Hexokinase [IPR001312]", "High mobility group protein HMG-I/HMG-Y, chordates [IPR031079]", "High mobility group protein HMGA [IPR000116]", "High mobility group protein HMGB1 [IPR031076]", "High mobility group protein HMGB3 [IPR031077]", "High mobility group protein HMGN [IPR000079]", "Higher eukaryotic phosphomevalonate kinase [IPR005919]", "Histidine phosphatase superfamily, clade-1 [IPR013078]", "Histidine phosphatase superfamily, clade-2 [IPR000560]", "Histidine triad (HIT) protein [IPR001310]", "Histone H2A [IPR002119]", "Histone H4 [IPR001951]", "Histone acetyltransferase type B, catalytic subunit [IPR017380]", "Histone deacetylase [IPR003084]", "Histone deacetylase complex, SAP18 subunit [IPR017250]", "Histone deacetylase family [IPR000286]", "Histone demethylase JHDM2-like [IPR045109]", "Histone lysine-specific demethylase [IPR017366]", "Histone-lysine N-methyltransferase 2A [IPR037927]", "Histone-lysine N-methyltransferase EHMT1 [IPR038035]", "Histone-lysine N-methyltransferase EHMT1/EHMT2 [IPR043550]", "Histone-lysine N-methyltransferase EHMT2 [IPR038034]", "Histone-lysine N-methyltransferase Smyd3 [IPR025805]", "Histone-lysine N-methyltransferase, SET [IPR017155]", "HnRNP R/Q splicing factor [IPR006535]", "HnRNP-L/PTB [IPR006536]", "Holocytochrome c/c1 synthase [IPR000511]", "Host cell factor 1 [IPR037854]", "Host cell factor [IPR043536]", "Hydantoinase/dihydropyrimidinase [IPR011778]", "Hydroxymethylglutaryl-CoA synthase, eukaryotic [IPR010122]", "Hypoxanthine phosphoribosyl transferase [IPR005904]", "I-BAR domain containing protein IRSp53 [IPR030128]", "I-BAR domain containing protein IRSp53/IRTKS/Pinkbar [IPR027681]", "ICln [IPR003521]", "ISC system FeS cluster assembly, IscU scaffold [IPR011339]", "Importin beta family [IPR040122]", "Importin subunit alpha [IPR024931]", "Inhibitor of nuclear factor kappa-B kinase-interacting protein [IPR024152]", "Initiation factor 2B alpha/beta/delta [IPR011559]", "Initiation factor 2B-related [IPR000649]", "Initiation factor 4G [IPR045208]", "Inner centromere protein [IPR039130]", "Inner nuclear membrane protein Man1 [IPR034997]", "Inorganic pyrophosphatase [IPR008162]", "Inosine triphosphate pyrophosphatase [IPR027502]", "Inosine-5'-monophosphate dehydrogenase [IPR005990]", "Inositol monophosphatase-like [IPR000760]", "Inositol-tetrakisphosphate 1-kinase [IPR008656]", "Insulin receptor substrate [IPR039011]", "Insulin-like growth factor 2 mRNA-binding protein 2 [IPR028743]", "Integral membrane protein EMC3/TMCO1-like [IPR002809]", "Integrator complex subunit 3 [IPR045334]", "Integrator complex subunit 9 [IPR027074]", "Integrin beta subunit [IPR015812]", "Integrin beta-1 subunit [IPR027071]", "Interferon-induced protein with tetratricopeptide repeat 5 [IPR024125]", "Interferon-inducible double-stranded RNA-dependent protein kinase activator A [IPR033363]", "Interleukin enhancer-binding factor 3 [IPR033099]", "Intracellular chloride channel [IPR002946]", "Intracellular lipid binding protein [IPR031259]", "Intraflagellar transport protein 27 homologue, eukaryotes [IPR034112]", "Intron Large complex component GCFC2-like [IPR012890]", "Inverted formin-2 [IPR027649]", "Iron-sulfur protein NUBPL-like [IPR044304]", "Isocitrate dehydrogenase NAD-dependent [IPR004434]", "Isocitrate dehydrogenase NADP-dependent [IPR004790]", "Isoleucine-tRNA ligase [IPR002301]", "Isoleucine-tRNA ligase, type 1 [IPR023585]", "Isoleucine-tRNA ligase, type 2 [IPR023586]", "Isopentenyl-diphosphate delta-isomerase, type 1 [IPR011876]", "Isoprenylcysteine carboxyl methyltransferase [IPR007269]", "Isovaleryl-CoA dehydrogenase [IPR034183]", "JNK-interacting protein 3/4 [IPR039911]", "Junction plakoglobin [IPR030461]", "Junctional adhesion molecule A [IPR042456]", "KH domain-containing BBP-like [IPR045071]", "KIF-1 binding protein [IPR022083]", "KRR1 interacting protein 1 [IPR018034]", "Kae1/TsaD family [IPR017861]", "Keratin, type I [IPR002957]", "Keratinocyte-associated transmembrane protein 2 [IPR037645]", "Kindlin/fermitin [IPR037843]", "Kinectin [IPR024854]", "Kinesin light chain [IPR002151]", "Kinesin-like protein KIF20A [IPR027326]", "Kinesin-like protein KIF22 (Kid) [IPR026986]", "Kinesin-like protein [IPR027640]", "Kinetochore Mis14/Nsl1 [IPR013950]", "Kinetochore protein Spc25 [IPR045143]", "Kinetochore-Ndc80 subunit Spc24 [IPR013252]", "Ku70 [IPR006165]", "Ku80 [IPR024193]", "Kynurenine--oxoglutarate transaminase 3 [IPR034612]", "L-lactate dehydrogenase [IPR011304]", "L-lactate/malate dehydrogenase [IPR001557]", "LAMTOR1/MEH1 [IPR028209]", "LETM1/MDM38-like [IPR044202]", "LIM domain and actin-binding protein 1 [IPR028740]", "LIM domain and actin-binding protein LIMA-like [IPR045268]", "LRP chaperone MESD [IPR019330]", "La domain containing protein [IPR045180]", "LanC-like protein, eukaryotic [IPR020464]", "Lanthionine synthetase C-like [IPR007822]", "Las1 [IPR007174]", "Lecithin:cholesterol/phospholipid:diacylglycerol acyltransferase [IPR003386]", "Lethal(2) giant larvae protein [IPR000664]", "Leucine zipper putative tumor suppressor [IPR045329]", "Leucine zipper putative tumour suppressor 2 [IPR028597]", "Leucine zipper transcription factor-like protein 1 [IPR026157]", "Leucine-rich PPR motif-containing protein [IPR033490]", "Leucine-rich repeat protein SHOC2 [IPR027036]", "Leucine-tRNA ligase [IPR002302]", "Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic [IPR004493]", "Leukocyte surface antigen CD47 [IPR006704]", "Leukotriene A4 hydrolase/leucine aminopeptidase [IPR012777]", "Leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase [IPR014190]", "Like-Sm (LSM) domain containing protein, LSm4/SmD1/SmD3 [IPR027141]", "Linker histone H1/H5 [IPR005819]", "Lipase, eukaryotic [IPR025483]", "Lipid droplet-associated hydrolase [IPR019363]", "Lon protease [IPR027065]", "Lon protease homologue, chloroplastic/mitochondrial [IPR027503]", "Lon protease, bacterial/eukaryotic-type [IPR004815]", "Long-chain fatty acid CoA synthetase, eukaryotic [IPR045311]", "Low temperature viability protein Ltv1 [IPR007307]", "Luc7-related [IPR004882]", "Lupus La protein [IPR002344]", "Lysine-tRNA ligase, class II [IPR002313]", "Lysophosphatidylserine lipase ABHD12 [IPR026605]", "Lysosomal thioesterase PPT2 [IPR030295]", "Lysosome membrane protein II [IPR005429]", "Lysosome-associated membrane glycoprotein [IPR002000]", "M-phase phosphoprotein 6 [IPR019324]", "MCT-1/Tma20 [IPR016437]", "MCU family [IPR039055]", "MDN2-binding protein [IPR039061]", "MICOS complex subunit MIC19/MIC25 [IPR007964]", "MICOS complex subunit MIC26/MIC27 [IPR019166]", "MICOS complex subunit MIC26/MIC27, animal [IPR033182]", "MICOS complex subunit Mic13 [IPR026769]", "MRG [IPR008676]", "MRPS27/PTCD2 [IPR034913]", "Macrophage migration inhibitory factor [IPR001398]", "Magnesium transporter NIPA [IPR008521]", "Major facilitator superfamily [IPR011701]", "Major facilitator, sugar transporter-like [IPR005828]", "Mak16 protein [IPR006958]", "Malate dehydrogenase, NAD-dependent, cytosolic [IPR011274]", "Malate dehydrogenase, type 1 [IPR010097]", "Malate dehydrogenase, type 2 [IPR010945]", "Malectin [IPR039155]", "Malic oxidoreductase [IPR001891]", "Manganese/iron superoxide dismutase [IPR001189]", "Mannose-6-phosphate isomerase [IPR016305]", "Mannose-6-phosphate isomerase, type I [IPR001250]", "Mannose-6-phosphate receptor [IPR028927]", "Matrix-remodeling-associated protein 7 [IPR026622]", "Med25/PTOV1 [IPR045105]", "Mediator complex, subunit Med17 [IPR019313]", "Mediator complex, subunit Med24, [IPR021429]", "Medium-chain dehydrogenase/reductase [IPR045010]", "Medium-chain specific acyl-CoA dehydrogenase [IPR034180]", "Melanoma-associated antigen D2 [IPR028810]", "Melanoma-associated antigen [IPR037445]", "Membrane insertase YidC/ALB3/OXA1/COX18 [IPR001708]", "Membrane bound O-acyl transferase, MBOAT [IPR004299]", "Membrane magnesium transporter [IPR018937]", "Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein [IPR001129]", "Mesoderm induction early response protein/metastasis-associated protein [IPR040138]", "Metal-dependent protein hydrolase [IPR003226]", "Metastasis-associated protein MTA2 [IPR037964]", "Methionine-tRNA ligase, type 1 [IPR023458]", "Methionyl-tRNA synthetase [IPR014758]", "Methyl-CpG binding protein MeCP2 [IPR017353]", "Methyl-CpG binding protein MeCP2/MBD4 [IPR045138]", "Methylcrotonoyl-CoA carboxylase beta chain MCCB/AccD1-like [IPR045190]", "Methylmalonate-semialdehyde dehydrogenase [IPR010061]", "Methylpurine-DNA glycosylase [IPR003180]", "Methylthioadenosine phosphorylase (MTAP) [IPR010044]", "Methylthioribose-1-phosphate isomerase [IPR005251]", "Methylthiotransferase [IPR005839]", "Methyltransferase, trithorax [IPR016569]", "Mevalonate kinase [IPR006205]", "Mevalonate/galactokinase [IPR006206]", "Mff/Tango-11 [IPR008518]", "MiaB-like tRNA modifying enzyme, archaeal-type [IPR006466]", "Microprocessor complex subunit DGCR8 [IPR040375]", "Microtubule associated protein 1 [IPR026074]", "Microtubule-associated protein 1B [IPR027321]", "Microtubule-associated protein 1S [IPR027322]", "Microtubule-associated protein 4 [IPR027323]", "Microtubule-associated protein Jupiter [IPR033335]", "Microtubule-associated protein RP/EB [IPR027328]", "Microtubule-associated protein, MAP65/Ase1/PRC1 [IPR007145]", "Midasin [IPR012099]", "Midline-1 [IPR027727]", "Mini-chromosome maintenance complex protein 4 [IPR008047]", "Mini-chromosome maintenance complex-binding protein [IPR019140]", "Mini-chromosome maintenance protein [IPR031327]", "Mitochondrial 18kDa protein [IPR019560]", "Mitochondrial 28S ribosomal protein S31 [IPR026299]", "Mitochondrial 28S ribosomal protein S34 [IPR032053]", "Mitochondrial ATP synthase subunit g, animal [IPR016702]", "Mitochondrial ATPase inhibitor [IPR007648]", "Mitochondrial F1-F0 ATP synthase subunit F, predicted [IPR019344]", "Mitochondrial Rho GTPase 1 [IPR029506]", "Mitochondrial Rho GTPase [IPR021181]", "Mitochondrial antiviral-signalling protein, metazoan [IPR026148]", "Mitochondrial carrier UCP-like [IPR002030]", "Mitochondrial carrier protein [IPR002067]", "Mitochondrial glycoprotein [IPR003428]", "Mitochondrial import inner membrane translocase subunit TIM22 [IPR039175]", "Mitochondrial import inner membrane translocase subunit Tim44 [IPR017303]", "Mitochondrial import inner membrane translocase subunit Tim50 [IPR027111]", "Mitochondrial import inner membrane translocase subunit Tim8/13 [IPR039238]", "Mitochondrial import receptor subunit TOM5, metazoa [IPR029179]", "Mitochondrial import receptor subunit Tom22 [IPR005683]", "Mitochondrial inner membrane protein Mitofilin [IPR019133]", "Mitochondrial inner membrane translocase complex, subunit Tim17 [IPR005678]", "Mitochondrial inner membrane translocase complex, subunit Tim23 [IPR005681]", "Mitochondrial outer membrane translocase complex, subunit Tom5 [IPR019603]", "Mitochondrial outer membrane transport complex protein, metaxin [IPR017410]", "Mitochondrial phosphate carrier protein Pic2/Mir1-like [IPR044677]", "Mitochondrial processing peptidase subunit beta [IPR037718]", "Mitochondrial-processing peptidase subunit alpha [IPR037715]", "Mitofusin family [IPR027094]", "Mitofusin-2 [IPR027089]", "Mitogen-activated protein (MAP) kinase kinase kinase 7 [IPR017421]", "Mitogen-activated protein (MAP) kinase p38-like [IPR008352]", "Mitogen-activated protein (MAP) kinase phosphatase [IPR008343]", "Mitogen-activated protein (MAP) kinase, ERK1/2 [IPR008349]", "Mitogen-activated protein kinase 14 [IPR038784]", "Mo25-like [IPR013878]", "Molecular chaperone regulator BAG [IPR039773]", "Molybdate-anion transporter [IPR008509]", "Molybdate-anion transporter, animal type [IPR030163]", "Monocarboxylate transporter 1 [IPR030757]", "Monocarboxylate transporter [IPR004743]", "Monothiol glutaredoxin-related [IPR004480]", "Mortality factor 4-like protein 1 [IPR038011]", "Mortality factor 4-like protein 2 [IPR038012]", "Mpv17/PMP22 [IPR007248]", "Mrp/NBP35 ATP-binding protein [IPR019591]", "Multi drug resistance-associated protein [IPR005292]", "Multidrug resistance protein 1 [IPR030258]", "Multifunctional methyltransferase subunit Trm112 [IPR039127]", "Multiple myeloma tumor-associated protein 2-like [IPR039207]", "Myelin expression factor 2 [IPR034632]", "Myeloid-derived growth factor [IPR018887]", "Myo-inositol-1-phosphate synthase [IPR002587]", "Myotubularin family [IPR030564]", "Myotubularin-related protein 6 [IPR030581]", "Myristoyl-CoA:protein N-myristoyltransferase [IPR000903]", "Myristoylated alanine-rich C-kinase substrate MARCKS [IPR002101]", "N-acetyl-D-glucosamine kinase NAGK-like [IPR039758]", "N-acetylglucosamine-6-sulfatase [IPR012251]", "N-acetylglucosamine-6-sulfatase, metazoan [IPR015981]", "N-acetyltransferase Ard1-like [IPR045047]", "N-acetyltransferase B complex, non-catalytic subunit [IPR019183]", "N-alpha-acetyltransferase 40 [IPR039949]", "N-terminal acetyltransferase A, auxiliary subunit [IPR021183]", "NAD kinase 2, mitochondrial [IPR012355]", "NAD kinase [IPR002504]", "NAD(P) transhydrogenase, alpha subunit [IPR026255]", "NAD(P)H-quinone oxidoreductase subunit D/H [IPR022885]", "NAD/FAD transporter SLC25A32-like [IPR044712]", "NADH dehydrogenase, subunit C [IPR010218]", "NADH ubiquinone oxidoreductase, F subunit [IPR011537]", "NADH-quinone oxidoreductase subunit E-like [IPR002023]", "NADH-ubiquinone oxidoreductase, 20 Kd subunit [IPR006138]", "NADH-ubiquinone oxidoreductase, subunit 10 [IPR019377]", "NADH-ubiquinone reductase complex 1 MLRQ subunit [IPR010530]", "NADH:cytochrome b5 reductase-like [IPR001834]", "NADH:ubiquinone oxidoreductase, ESSS subunit [IPR019329]", "NADH:ubiquinone oxidoreductase, subunit G [IPR010228]", "NADH:ubiquinone oxidoreductase, subunit NDUFB4 [IPR009866]", "NADPH-cytochrome P450 reductase [IPR023208]", "NDRG [IPR004142]", "NEDD8 ultimate buster 1 [IPR039749]", "NEDD8-activating enzyme E1 catalytic subunit [IPR030468]", "NEDD8-activating enzyme E1 regulatory subunit APP-BP1 [IPR030667]", "NOL6/Upt22 [IPR005554]", "NPC1-like [IPR004765]", "NSF attachment protein [IPR000744]", "Na(+)/H(+) exchange regulatory cofactor NHERF-1 [IPR031199]", "Na(+)/H(+) exchange regulatory cofactor NHERF-1/2 [IPR017300]", "Nck-associated protein 1 [IPR019137]", "Negative elongation factor E [IPR033102]", "Nesprin-2 [IPR030266]", "Nestin [IPR031211]", "Neurochondrin [IPR008709]", "Neurofilament light polypeptide [IPR027692]", "Neurofilament medium polypeptide [IPR027697]", "Neuroplastin [IPR027112]", "Nibrin [IPR016592]", "Nibrin-related [IPR040227]", "Nicalin [IPR016574]", "Nicastrin [IPR008710]", "Nicotinamide phosphoribosyl transferase [IPR016471]", "Nitric oxide synthase-interacting protein [IPR016818]", "Nonaspanin (TM9SF) [IPR004240]", "Nonsense-mediated mRNA decay protein 3 [IPR039722]", "Nonsense-mediated mRNA decay protein Nmd2/UPF2 [IPR039762]", "Nuclear RNA export factor [IPR030217]", "Nuclear RNA-splicing-associated protein, SR-25 [IPR019532]", "Nuclear cap-binding protein subunit 1 [IPR027159]", "Nuclear factor hnRNPA1 [IPR021662]", "Nuclear fragile X mental retardation-interacting protein 2 [IPR032747]", "Nuclear mitotic apparatus protein 1 [IPR026650]", "Nuclear polyadenylated RNA-binding protein Nab2/ZC3H14 [IPR040366]", "Nuclear pore complex protein NUP98-NUP96 [IPR037637]", "Nuclear pore complex protein Nup133-like [IPR037624]", "Nuclear pore complex protein [IPR026054]", "Nuclear pore glycoprotein p62, metazoa [IPR033072]", "Nuclear pore membrane glycoprotein 210-like [IPR045197]", "Nuclear pore protein 84/107 [IPR007252]", "Nuclear protein DGCR14/ESS-2 [IPR019148]", "Nuclear protein localization protein 4 [IPR016563]", "Nuclear transport factor 2/Mtr2 [IPR045875]", "Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 [IPR026633]", "Nucleobindin [IPR040250]", "Nucleobindin-1 [IPR040253]", "Nucleobindin-2 [IPR028813]", "Nucleolar GTP-binding protein 1 [IPR024926]", "Nucleolar GTP-binding protein 2 [IPR024929]", "Nucleolar complex protein 2 [IPR005343]", "Nucleolar complex protein 4 [IPR027193]", "Nucleolar complex-associated protein 3 [IPR016903]", "Nucleolar pre-ribosomal-associated protein 1 [IPR039844]", "Nucleolar protein 11 [IPR042859]", "Nucleolar protein 14 [IPR007276]", "Nucleolar protein 7 [IPR039626]", "Nucleolar protein Nop56/Nop58 [IPR045056]", "Nucleolar, Nop52 [IPR010301]", "Nucleoplasmin family [IPR004301]", "Nucleoporin NSP1/NUP62 [IPR026010]", "Nucleoporin NUP88/NUP82 [IPR037700]", "Nucleoporin Nup120/160 [IPR021717]", "Nucleoporin Nup186/Nup192/Nup205 [IPR021827]", "Nucleoporin Nup188 [IPR044840]", "Nucleoporin Nup37 [IPR037626]", "Nucleoporin Nup54/Nup57/Nup44 [IPR024864]", "Nucleoporin Nup85-like [IPR011502]", "Nucleoporin Nup88 [IPR019321]", "Nucleoporin Seh1 [IPR037597]", "Nucleoporin interacting component Nup93/Nic96 [IPR007231]", "Nucleoporin p58/p45 [IPR024882]", "Nucleoporin peptidase S59-like [IPR037665]", "Nucleoporin protein Ndc1-Nup [IPR019049]", "Nucleoporin, NUP53 [IPR017389]", "Nucleoporin, Nup155-like [IPR004870]", "Nucleoside 2-deoxyribosyltransferase [IPR007710]", "Nucleoside diphosphate kinase [IPR001564]", "Nucleoside transporter ENT1/ENT2 [IPR034764]", "Nucleoside-triphosphatase, THEP1 type [IPR004948]", "Nucleosome assembly protein (NAP) [IPR002164]", "NudC domain-containing protein 1 [IPR037895]", "NudC family [IPR037898]", "OBG-type GTPase [IPR045086]", "OCIA domain-containing protein 1/2 [IPR040187]", "ODR-4-like [IPR029454]", "Oligoribonuclease [IPR022894]", "Oligosaccharyl transferase, STT3 subunit [IPR003674]", "Optic atrophy 3-like [IPR010754]", "Origin recognition complex, subunit 3 [IPR020795]", "Ornithine aminotransferase [IPR010164]", "Orotate phosphoribosyltransferase [IPR023031]", "Orotidine 5'-phosphate decarboxylase [IPR014732]", "Oxidized purine nucleoside triphosphate [IPR003563]", "Oxysterol-binding protein [IPR000648]", "P-type ATPase [IPR001757]", "P-type ATPase subfamily IIC, subunit alpha [IPR005775]", "P-type ATPase, subfamily IIA, SERCA-type [IPR005782]", "P-type ATPase, subfamily V [IPR006544]", "P-type ATPase, subfamily IB [IPR027256]", "P-type ATPase, subfamily IIA, PMR1-type [IPR006413]", "P-type ATPase, subfamily IIB [IPR006408]", "PA2G4 family [IPR004545]", "PAT complex subunit CCDC47 [IPR012879]", "PCNA-associated factor [IPR040444]", "PDCD5-like [IPR002836]", "PDK/BCKDK protein kinase [IPR039028]", "PDZ and LIM domain protein 1 [IPR028537]", "PEST proteolytic signal-containing nuclear protein [IPR029169]", "PEX5/PEX5L [IPR024111]", "PH-interacting protein [IPR028738]", "PHF5-like [IPR005345]", "PITH domain-containing protein 1-like [IPR045099]", "PP2B [IPR043360]", "Pachytene checkpoint protein 2-like [IPR044539]", "Palmitoyl protein thioesterase [IPR002472]", "Palmitoyl-protein thioesterase 1 [IPR030294]", "Palmitoyltransferase ZDHHC13 [IPR030290]", "Pantothenate kinase, acetyl-CoA regulated, two-domain type [IPR015844]", "Paraneoplastic encephalomyelitis antigen [IPR002343]", "Paraoxonase2 [IPR008364]", "Pat1-like [IPR039900]", "Paxillin [IPR001904]", "Pentatricopeptide repeat domain-containing protein 3 [IPR037387]", "Peptidase A22B, signal peptide peptidase [IPR007369]", "Peptidase C13, legumain [IPR001096]", "Peptidase C14 family [IPR002398]", "Peptidase C1B, bleomycin hydrolase [IPR004134]", "Peptidase C2, calpain family [IPR022684]", "Peptidase C26 [IPR011697]", "Peptidase C26, gamma-glutamyl hydrolase [IPR015527]", "Peptidase C54 [IPR005078]", "Peptidase C65, otubain [IPR019400]", "Peptidase C69, dipeptidase A [IPR005322]", "Peptidase C78, ubiquitin fold modifier-specific peptidase 1/ 2 [IPR012462]", "Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930]", "Peptidase M1, aminopeptidase B [IPR015571]", "Peptidase M13 [IPR000718]", "Peptidase M14B, caboxypeptidase D [IPR015567]", "Peptidase M17, leucine aminopeptidase [IPR023042]", "Peptidase M17, leucine aminopeptidase/peptidase B [IPR011356]", "Peptidase M20 [IPR002933]", "Peptidase M28 family [IPR045175]", "Peptidase M3A/M3B [IPR045090]", "Peptidase S10, serine carboxypeptidase [IPR001563]", "Peptidase S26B [IPR001733]", "Peptidase S28 [IPR008758]", "Peptidase S8, subtilisin-related [IPR015500]", "Peptidase S9A, prolyl oligopeptidase [IPR002470]", "Peptidase T1A, proteasome beta-subunit [IPR000243]", "Peptidase T2, asparaginase 2 [IPR000246]", "Peptidase family M49 [IPR039461]", "Peptidase, FtsH [IPR005936]", "Peptide chain release factor eRF1/aRF1 [IPR004403]", "Peptidyl-prolyl cis-trans isomerase FKBP2/11 [IPR044609]", "Peptidyl-prolyl cis-trans isomerase FKBP3 [IPR043368]", "Peptidyl-prolyl cis-trans isomerase FKBP4 [IPR031212]", "Peptidyl-prolyl cis-trans isomerase FKBP5 [IPR031210]", "Peptidyl-prolyl cis-trans isomerase PIN4 [IPR043323]", "Peptidyl-tRNA hydrolase, PTH2 [IPR002833]", "Pericentriolar material 1 protein [IPR024138]", "Perilipin [IPR004279]", "Periodic tryptophan protein 1 [IPR044285]", "Periodic tryptophan protein 2 [IPR027145]", "Periphilin-1 [IPR028851]", "Peroxiredoxin, AhpC-type [IPR024706]", "Peroxiredoxin-5-like [IPR037944]", "Peroxisomal acyl-coenzyme A oxidase [IPR034171]", "Peroxisomal membrane protein 14 [IPR025655]", "Peroxisomal targeting signal 1 receptor PEX5, animals [IPR024113]", "Peroxysomal long chain fatty acyl transporter [IPR005283]", "Pescadillo [IPR010613]", "Pex19 protein [IPR006708]", "Phenylalanine-tRNA ligase, class IIc, beta subunit [IPR045060]", "Phenylalanyl-tRNA synthetase, class IIc, alpha subunit [IPR004529]", "Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archael/eukaryotic type [IPR004531]", "Phosducin-like [IPR045037]", "Phosphatidate cytidylyltransferase [IPR000374]", "Phosphatidate cytidylyltransferase, eukaryota [IPR016720]", "Phosphatidate cytidylyltransferase, mitochondrial [IPR015222]", "Phosphatidyl serine synthase [IPR004277]", "Phosphatidylethanolamine-binding protein [IPR008914]", "Phosphatidylethanolamine-binding protein, eukaryotic [IPR035810]", "Phosphatidylinositol kinase [IPR015433]", "Phosphatidylinositol transfer protein [IPR001666]", "Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma [IPR016279]", "Phosphatidylinositol-binding clathrin assembly protein [IPR030412]", "Phosphatidylinositol-glycan biosynthesis class S protein [IPR019540]", "Phosphatidylserine decarboxylase [IPR033177]", "Phosphatidylserine decarboxylase, eukaryotic type 1 [IPR033661]", "Phosphatidylserine decarboxylase-related [IPR003817]", "Phosphoacetylglucosamine mutase [IPR016657]", "Phosphodiesterase MJ0936/Vps29 [IPR000979]", "Phosphoenolpyruvate carboxykinase, GTP-utilising [IPR008209]", "Phosphoglucomutase [IPR045244]", "Phosphoglucose isomerase (PGI) [IPR001672]", "Phosphoglycerate kinase [IPR001576]", "Phosphoglycerate mutase 1 [IPR005952]", "Phosphoinositide phospholipase C family [IPR001192]", "Phospholipase B-like [IPR007000]", "Phosphoribosylformylglycinamidine cyclo-ligase [IPR004733]", "Phosphoribosylformylglycinamidine synthase PurL [IPR010073]", "Phosphoribosylglycinamide formyltransferase [IPR004607]", "Phosphoribosylglycinamide synthetase [IPR000115]", "Phosphorylated adapter RNA export protein [IPR039047]", "Phosphoserine aminotransferase [IPR022278]", "Phosphotyrosyl phosphatase activator, PTPA [IPR004327]", "Pinin [IPR039853]", "Pirin [IPR012093]", "Plakin [IPR043197]", "Plakophilin/Delta catenin [IPR028435]", "Plasma membrane calcium-transporting ATPase 1 [IPR030320]", "Plasminogen activator inhibitor 1 RNA-binding protein [IPR027205]", "Plastin-1 [IPR030235]", "Plastin-2/3 [IPR039956]", "Plectin [IPR030269]", "Polo kinase kinase [IPR022165]", "Poly(A) polymerase [IPR014492]", "Poly-U binding splicing factor, PUF60-like [IPR006532]", "Polyadenylate binding protein, human types 1, 2, 3, 4 [IPR006515]", "Polyadenylate-binding protein 2 [IPR034911]", "Polyprenyl synthetase [IPR000092]", "Polyribonucleotide 5-hydroxyl-kinase Clp1 [IPR028606]", "Polyribonucleotide 5-hydroxyl-kinase Clp1/Grc3 [IPR045116]", "Polyribonucleotide nucleotidyltransferase [IPR012162]", "Porin, eukaryotic type [IPR001925]", "Pre-mRNA 3' end processing protein Pfs2-like [IPR045245]", "Pre-mRNA-processing factor 19 [IPR038959]", "Pre-mRNA-processing factor 6/Prp1/STA1 [IPR027108]", "Pre-mRNA-processing factor Prp40 [IPR039726]", "Pre-mRNA-processing-splicing factor 8 [IPR027652]", "Pre-mRNA-splicing factor 38 [IPR005037]", "Pre-mRNA-splicing factor Isy1 [IPR009360]", "Pre-mRNA-splicing factor SPF27 [IPR008409]", "Pre-mRNA-splicing factor Spp2-like [IPR045166]", "Pre-mRNA-splicing factor Syf1-like [IPR045075]", "Pre-mRNA-splicing regulator WTAP [IPR033757]", "Pre-rRNA-processing protein PNO1-like [IPR039912]", "Prefoldin alpha subunit, archaea-type [IPR011599]", "Prefoldin alpha-like [IPR004127]", "Prefoldin beta-like [IPR002777]", "Prefoldin subunit 2 [IPR027235]", "Prefoldin subunit 3 [IPR016655]", "Prenylated rab acceptor PRA1 [IPR004895]", "Prenylcysteine oxidase [IPR017046]", "Prenyltransferase subunit beta [IPR045089]", "Presenilin/signal peptide peptidase [IPR006639]", "Primosome PriB/single-strand DNA-binding [IPR000424]", "Probable ubiquitin carboxyl-terminal hydrolase FAF-X [IPR031226]", "Profilin [IPR005455]", "Profilin-1 [IPR029892]", "Profilin-2 [IPR029891]", "Profilin1/2/3, vertebrate [IPR005454]", "Programmed cell death protein 4 [IPR039778]", "Prohibitin [IPR000163]", "Proliferating cell nuclear antigen, PCNA [IPR000730]", "Proline-rich AKT1 substrate 1 protein [IPR026682]", "Proline-tRNA ligase, class IIa, archaeal-type [IPR004499]", "Prolyl 3-hydroxylase 1 [IPR039837]", "Prolyl 3-hydroxylase [IPR039575]", "Prolyl 4-hydroxylase [IPR045054]", "Prostaglandin E synthase 2 [IPR034334]", "Prostaglandin reductase 2 [IPR037399]", "Proteasomal ubiquitin receptor Rpn13/ADRM1 [IPR006773]", "Proteasome B-type subunit [IPR023333]", "Proteasome activator PA28 [IPR009077]", "Proteasome activator complex subunit 4 [IPR035309]", "Proteasome alpha-type subunit [IPR023332]", "Proteasome assembly chaperone 1 [IPR016565]", "Proteasome assembly chaperone 2 [IPR019151]", "Proteasome assembly chaperone 2, eukaryotic [IPR016562]", "Proteasome assembly chaperone 3 [IPR018788]", "Proteasome beta 3 subunit [IPR033811]", "Proteasome component Ecm29 [IPR024372]", "Proteasome inhibitor PI31-like [IPR045128]", "Proteasome subunit alpha 1 [IPR035144]", "Proteasome subunit alpha 3 [IPR037555]", "Proteasome subunit alpha 7 [IPR035190]", "Proteasome subunit alpha2 [IPR034644]", "Proteasome subunit alpha4 [IPR034647]", "Proteasome subunit alpha5 [IPR033812]", "Proteasome subunit alpha6 [IPR034642]", "Proteasome subunit beta 1 [IPR035202]", "Proteasome subunit beta 2 [IPR035206]", "Proteasome subunit beta 4 [IPR016295]", "Proteasome subunit beta 5 [IPR037558]", "Proteasome subunit beta 6 [IPR035140]", "Proteasome subunit beta 7 [IPR035216]", "Proteasome, subunit alpha/beta [IPR001353]", "Protein AATF/Bfr2 [IPR039223]", "Protein BRAWNIN [IPR027858]", "Protein CDV3 [IPR026806]", "Protein CIP2A [IPR042510]", "Protein CUSTOS [IPR026694]", "Protein Cms1 [IPR032704]", "Protein DEK [IPR044198]", "Protein ERGIC-53 [IPR033085]", "Protein FAM3C [IPR039219]", "Protein FAM8A1 [IPR039871]", "Protein FRG1 [IPR010414]", "Protein Hgh1 [IPR039717]", "Protein ICln/Lot5/Saf5 [IPR039924]", "Protein LYRIC [IPR031402]", "Protein Lsm12-like [IPR039683]", "Protein NDRG3 [IPR030692]", "Protein PBDC1, metazoa/fungi [IPR008476]", "Protein PRRC1 [IPR026534]", "Protein PRRC2 [IPR033184]", "Protein Peter Pan-like [IPR045112]", "Protein RCC2 [IPR028641]", "Protein Red-like [IPR039896]", "Protein S100-A10 [IPR028476]", "Protein S100-A11 [IPR028482]", "Protein SON [IPR032922]", "Protein Sgt1-like [IPR044563]", "Protein TFG [IPR033512]", "Protein XRP2 [IPR039093]", "Protein arginine N-methyltransferase PRMT5 [IPR007857]", "Protein arginine N-methyltransferase [IPR025799]", "Protein arginine methyltransferase NDUFAF7 [IPR003788]", "Protein canopy homolog [IPR042415]", "Protein disulfide-isomerase A6-like [IPR044569]", "Protein disulphide isomerase [IPR005792]", "Protein disulphide-isomerase A4 [IPR017068]", "Protein farnesyltransferase subunit beta [IPR026872]", "Protein flightless-1 [IPR029919]", "Protein import receptor MAS20 [IPR002056]", "Protein import receptor MAS20, metazoan [IPR022422]", "Protein kinase C and casein kinase substrate in neurons protein 2 [IPR028521]", "Protein kinase Mps1 family [IPR027084]", "Protein of unknown function DUF1075 [IPR009432]", "Protein of unknown function DUF2046 [IPR019152]", "Protein of unknown function DUF719 [IPR007998]", "Protein of unknown function DUF842, eukaryotic [IPR008560]", "Protein patched/dispatched [IPR003392]", "Protein phosphatase 2A regulatory subunit PR55 [IPR000009]", "Protein phosphatase 2A, regulatory B subunit, B56 [IPR002554]", "Protein phosphatase 2C family [IPR015655]", "Protein phosphatase methylesterase, eukaryotic [IPR016812]", "Protein regulator of cytokinesis 1 [IPR032921]", "Protein transport Sec61-beta/Sbh [IPR030671]", "Protein transport protein SEC31-like [IPR040251]", "Protein transport protein Sec23 [IPR037364]", "Protein transport protein SecG/Sec61-beta/Sbh [IPR016482]", "Protein unc-119 homologue A-like [IPR032977]", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase [IPR000682]", "Protein-S-isoprenylcysteine O-methyltransferase [IPR025770]", "Protein-glutamate O-methyltransferase [IPR039763]", "Protein-tyrosine phosphatase, low molecular weight [IPR017867]", "Protein-tyrosine phosphatase, low molecular weight, mammalian [IPR002115]", "Protein-tyrosine phosphatase, non-receptor type-1/2 [IPR012265]", "Protein-tyrosine phosphatase, non-receptor type-6, -11 [IPR012152]", "Protein-tyrosine phosphatase-like, PTPLA [IPR007482]", "Protein/nucleic acid deglycase DJ-1 [IPR006287]", "Proteinase inhibitor I25A, stefin [IPR001713]", "Protoporphyrinogen oxidase [IPR004572]", "Pseudouridine synthase I, TruA [IPR001406]", "Pseudouridine synthase PUS1/ PUS2-like [IPR041708]", "Pseudouridine synthase, TruD [IPR001656]", "Pterin 4 alpha carbinolamine dehydratase [IPR001533]", "Pumilio homologue 3 [IPR040059]", "Purine 5'-nucleotidase [IPR016695]", "Purine nucleoside phosphorylase I, inosine/guanosine-specific [IPR011270]", "Purine nucleoside phosphorylase [IPR011268]", "Purine-rich element binding protein family [IPR006628]", "Purine-rich element-binding protein alpha [IPR030500]", "Putative RNA methyltransferase [IPR003750]", "Pyridine nucleotide-disulphide oxidoreductase, class I [IPR001100]", "Pyridoxal phosphate-dependent decarboxylase [IPR002129]", "Pyridoxamine 5'-phosphate oxidase [IPR000659]", "Pyridoxine kinase [IPR004625]", "Pyrimidine 5'-nucleotidase, eukaryotic [IPR006434]", "Pyrroline-5-carboxylate reductase [IPR000304]", "Pyruvate carboxylase [IPR005930]", "Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y [IPR017597]", "Pyruvate dehydrogenase E1 component subunit beta [IPR027110]", "Pyruvate kinase [IPR001697]", "Queuine tRNA-ribosyltransferase accessory subunit QTRTD1 [IPR028592]", "Quinone oxidoreductase-like protein 1 [IPR042633]", "RAD3/XPD family [IPR001945]", "RAD51-associated protein 1 [IPR026632]", "RINT-1/Tip20 [IPR007528]", "RLI1 [IPR013283]", "RNA (C5-cytosine) methyltransferase [IPR023267]", "RNA (C5-cytosine) methyltransferase, NOP2 [IPR023273]", "RNA 3'-terminal phosphate cyclase [IPR000228]", "RNA 3'-terminal phosphate cyclase type 2 [IPR016443]", "RNA binding protein HABP4/SERBP1 [IPR039764]", "RNA cytidine acetyltransferase NAT10 [IPR033688]", "RNA demethylase ALKBH5 [IPR032860]", "RNA exonuclease 4 [IPR034920]", "RNA methyltransferase Bin3-like [IPR039772]", "RNA polymerase I associated factor, A49-like [IPR009668]", "RNA polymerase II associated factor Paf1 [IPR007133]", "RNA polymerase II transcription factor SIII, subunit A [IPR010684]", "RNA polymerase II transcriptional coactivator Sub1/Tcp4-like [IPR045125]", "RNA polymerase subunit Rpb7-like [IPR045113]", "RNA polymerase-associated protein Ctr9 [IPR031101]", "RNA transcription, translation and transport factor protein [IPR019265]", "RNA-binding motif protein 8 [IPR008111]", "RNA-binding protein 10 [IPR033095]", "RNA-binding protein 26 [IPR034861]", "RNA-binding protein 26/27 [IPR045137]", "RNA-binding protein EWS [IPR033109]", "RNA-binding protein FUS [IPR034459]", "RNA-binding protein Nova-2 [IPR033087]", "RNA-induced silencing complex, nuclease component Tudor-SN [IPR016685]", "RNA-splicing ligase RtcB homologue, eukaryotic [IPR027513]", "RNA-splicing ligase, RtcB [IPR001233]", "RNase P subunit p30 [IPR002738]", "ROK family [IPR000600]", "RPA-related protein RADX [IPR040893]", "RSBN1/Dpy-21 [IPR026306]", "RZZ complex, subunit Zw10 [IPR009361]", "Rab GDI protein [IPR000806]", "Rab GTPase-activating protein 1 [IPR033185]", "Rab21 [IPR041833]", "Rab24 [IPR041828]", "Rab3 [IPR037872]", "Rab35 [IPR041815]", "Rab39 [IPR041818]", "Rab3GAP catalytic subunit [IPR045700]", "Rab3GAP regulatory subunit [IPR026059]", "Rad21/Rec8-like protein [IPR039781]", "Ragulator complex protein LAMTOR2-like [IPR037587]", "Ran GTPase [IPR002041]", "Ran binding protein RanBP1-like [IPR045255]", "Rap guanine nucleotide exchange factor 2 [IPR030739]", "Rap1 GTPase-GDP dissociation stimulator 1 [IPR040144]", "Ras GTPase GNL1-like [IPR043358]", "Ras GTPase-activating protein 1 [IPR028554]", "Ras GTPase-activating protein [IPR039360]", "Ras GTPase-activating protein-binding protein 1 [IPR034375]", "Ras GTPase-activating protein-binding protein 2 [IPR034377]", "Ras GTPase-activating protein-binding protein [IPR039539]", "Ras-like guanine nucleotide exchange factor [IPR008937]", "Ras-related protein Rab14 [IPR030702]", "Reduced folate carrier [IPR002666]", "Reduced folate transporter SLC19A1 [IPR028339]", "Refilin family [IPR028215]", "Remodeling and spacing factor 1-like [IPR028938]", "Remodelling complex subunit Rsc/polybromo [IPR037382]", "Replication factor A protein 1 [IPR004591]", "Replication factor A protein 2 [IPR014646]", "Replication factor A protein 3 [IPR013970]", "Replication factor A protein-like [IPR040260]", "Replication factor C subunit 1 [IPR012178]", "Replication termination factor 2 [IPR006735]", "Reticulon-4-interacting protein 1 [IPR037397]", "Reticulophagy receptor 1/3 [IPR043384]", "Reticulophagy regulator 3 [IPR033361]", "Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit [IPR017287]", "Retinoblastoma-binding protein 5/Swd1 [IPR037850]", "Retinol-binding protein 1 [IPR031264]", "Retrieval of early ER protein Rer1 [IPR004932]", "Rho protein GDP-dissociation inhibitor [IPR000406]", "Rho-associated protein kinase 1/2 [IPR020684]", "Rho-related GTP-binding protein RhoG [IPR042734]", "Ribonuclease CAF1 [IPR006941]", "Ribonuclease H2 subunit B [IPR040456]", "Ribonuclease H2, subunit A [IPR004649]", "Ribonuclease HII/HIII [IPR001352]", "Ribonuclease III [IPR011907]", "Ribonuclease T2, eukaryotic [IPR033697]", "Ribonuclease T2-like [IPR001568]", "Ribonucleases P/MRP protein subunit Pop1 [IPR039182]", "Ribonucleoprotein PTB-binding 1 [IPR034635]", "Ribonucleoside-diphosphate reductase large subunit [IPR039718]", "Ribonucleotide reductase small subunit [IPR033909]", "Ribonucleotide reductase small subunit family [IPR000358]", "Ribophorin I [IPR007676]", "Ribose-phosphate pyrophosphokinase [IPR005946]", "Ribosomal RNA assembly KRR1 [IPR024166]", "Ribosomal RNA large subunit methyltransferase E [IPR015507]", "Ribosomal RNA processing protein 8 [IPR007823]", "Ribosomal RNA-processing protein 15 [IPR012459]", "Ribosomal RNA-processing protein Rrp9-like [IPR039241]", "Ribosomal biogenesis NSA2 family [IPR039411]", "Ribosomal biogenesis regulatory protein [IPR007023]", "Ribosomal biogenesis, methyltransferase, EMG1/NEP1 [IPR005304]", "Ribosomal protein L1 [IPR002143]", "Ribosomal protein L1, mitochondrial [IPR005879]", "Ribosomal protein L1/ribosomal biogenesis protein [IPR028364]", "Ribosomal protein L10P [IPR001790]", "Ribosomal protein L10e [IPR001197]", "Ribosomal protein L11, bacterial-type [IPR006519]", "Ribosomal protein L11/L12 [IPR000911]", "Ribosomal protein L12/P1/P2 family [IPR027534]", "Ribosomal protein L13 [IPR005822]", "Ribosomal protein L13, eukaryotic/archaeal [IPR005755]", "Ribosomal protein L13e [IPR001380]", "Ribosomal protein L14 [IPR039660]", "Ribosomal protein L14P [IPR000218]", "Ribosomal protein L15 [IPR030878]", "Ribosomal protein L15, bacterial-type [IPR005749]", "Ribosomal protein L15e [IPR000439]", "Ribosomal protein L17 [IPR000456]", "Ribosomal protein L18e [IPR000039]", "Ribosomal protein L19 [IPR001857]", "Ribosomal protein L2 [IPR002171]", "Ribosomal protein L2, archaeal-type [IPR023672]", "Ribosomal protein L21 [IPR001787]", "Ribosomal protein L21-like [IPR028909]", "Ribosomal protein L21e [IPR001147]", "Ribosomal protein L22/L17 [IPR001063]", "Ribosomal protein L22/L17, eukaryotic/archaeal [IPR005721]", "Ribosomal protein L22e [IPR002671]", "Ribosomal protein L23 [IPR019985]", "Ribosomal protein L24e-related [IPR000988]", "Ribosomal protein L25/L23 [IPR013025]", "Ribosomal protein L26/L24, eukaryotic/archaeal [IPR005756]", "Ribosomal protein L27e [IPR001141]", "Ribosomal protein L28/L24 [IPR026569]", "Ribosomal protein L28/L40, mitochondrial [IPR019192]", "Ribosomal protein L28e [IPR002672]", "Ribosomal protein L29/L35 [IPR001854]", "Ribosomal protein L29e [IPR002673]", "Ribosomal protein L3 [IPR000597]", "Ribosomal protein L3, archaeal/eukaryotic type [IPR045077]", "Ribosomal protein L3, bacterial/organelle-type [IPR019927]", "Ribosomal protein L30/YlxQ [IPR039109]", "Ribosomal protein L30e [IPR000231]", "Ribosomal protein L31e [IPR000054]", "Ribosomal protein L32e [IPR001515]", "Ribosomal protein L34Ae [IPR008195]", "Ribosomal protein L35A [IPR001780]", "Ribosomal protein L36e [IPR000509]", "Ribosomal protein L37/S30 [IPR010793]", "Ribosomal protein L37ae [IPR002674]", "Ribosomal protein L37e [IPR001569]", "Ribosomal protein L38e [IPR002675]", "Ribosomal protein L4, eukaryotic and archaeal type [IPR045240]", "Ribosomal protein L4/L1e [IPR002136]", "Ribosomal protein L44e [IPR000552]", "Ribosomal protein L5 [IPR002132]", "Ribosomal protein L5 eukaryotic/L18 archaeal [IPR005485]", "Ribosomal protein L50, mitochondria [IPR018305]", "Ribosomal protein L6 [IPR000702]", "Ribosomal protein L7, eukaryotic [IPR005998]", "Ribosomal protein L7/L12 [IPR000206]", "Ribosomal protein L7/L30 [IPR039699]", "Ribosomal protein L7A/L8 [IPR001921]", "Ribosomal protein L7Ae/L8/Nhp2 family [IPR018492]", "Ribosomal protein L9 [IPR000244]", "Ribosomal protein P2 [IPR044076]", "Ribosomal protein S10 [IPR001848]", "Ribosomal protein S10, eukaryotic/archaeal [IPR005729]", "Ribosomal protein S11 [IPR001971]", "Ribosomal protein S12/S23 [IPR006032]", "Ribosomal protein S12e [IPR000530]", "Ribosomal protein S13 [IPR001892]", "Ribosomal protein S15 [IPR000589]", "Ribosomal protein S15, bacterial-type [IPR005290]", "Ribosomal protein S15P [IPR023029]", "Ribosomal protein S17, archaeal/eukaryotic [IPR028333]", "Ribosomal protein S17/S11 [IPR000266]", "Ribosomal protein S17e [IPR001210]", "Ribosomal protein S19/S15 [IPR002222]", "Ribosomal protein S19A/S15e [IPR005713]", "Ribosomal protein S19e [IPR001266]", "Ribosomal protein S2 [IPR001865]", "Ribosomal protein S2, bacteria/mitochondria/plastid [IPR005706]", "Ribosomal protein S2, eukaryotic [IPR027498]", "Ribosomal protein S2, eukaryotic/archaeal [IPR005707]", "Ribosomal protein S21e [IPR001931]", "Ribosomal protein S22, mitochondrial [IPR019374]", "Ribosomal protein S23, eukaryotic/archaeal [IPR005680]", "Ribosomal protein S23, mitochondrial [IPR019520]", "Ribosomal protein S23/S29, mitochondrial [IPR019368]", "Ribosomal protein S24/S35, mitochondrial [IPR039848]", "Ribosomal protein S24e [IPR001976]", "Ribosomal protein S25 [IPR004977]", "Ribosomal protein S26e [IPR000892]", "Ribosomal protein S28, mitochondrial [IPR019375]", "Ribosomal protein S28e [IPR000289]", "Ribosomal protein S29, mitochondrial [IPR008092]", "Ribosomal protein S3, eukaryotic/archaeal [IPR005703]", "Ribosomal protein S30 [IPR006846]", "Ribosomal protein S30, mitochondrial [IPR039982]", "Ribosomal protein S3Ae [IPR001593]", "Ribosomal protein S4/S9 [IPR022801]", "Ribosomal protein S4/S9, eukaryotic/archaeal [IPR005710]", "Ribosomal protein S4e [IPR000876]", "Ribosomal protein S5 [IPR000851]", "Ribosomal protein S5, eukaryotic/archaeal [IPR005711]", "Ribosomal protein S5/S7 [IPR000235]", "Ribosomal protein S5/S7, eukaryotic/archaeal [IPR005716]", "Ribosomal protein S6 kinase II [IPR016239]", "Ribosomal protein S6, eukaryotic [IPR014401]", "Ribosomal protein S6e [IPR001377]", "Ribosomal protein S7e [IPR000554]", "Ribosomal protein S8 [IPR000630]", "Ribosomal protein S8e [IPR001047]", "Ribosomal protein S8e/ribosomal biogenesis NSA2 [IPR022309]", "Ribosomal protein S9 [IPR000754]", "Ribosome assembly factor Mrt4 [IPR033867]", "Ribosome biogenesis factor, NIP7 [IPR016686]", "Ribosome biogenesis protein BRX1 [IPR026532]", "Ribosome biogenesis protein Bms1/Tsr1 [IPR039761]", "Ribosome biogenesis protein Nop16 [IPR019002]", "Ribosome biogenesis protein Nop53/GLTSCR2 [IPR011687]", "Ribosome biogenesis protein Rpf2 [IPR039770]", "Ribosome maturation protein Sdo1/SBDS [IPR002140]", "Ribosome maturation protein Sdo1/SBDS-like [IPR039100]", "Ribosome recycling factor [IPR002661]", "Ribosome-binding ATPase YchF/Obg-like ATPase 1 [IPR004396]", "Ribosome-binding protein 1 [IPR040248]", "RidA family [IPR006056]", "Rieske iron-sulphur protein [IPR014349]", "RuvB-like [IPR027238]", "RuvB-like helicase 1 [IPR037938]", "RuvB-like helicase 2 [IPR037942]", "S-adenosylmethionine synthetase [IPR002133]", "S-formylglutathione hydrolase [IPR014186]", "S-phase kinase-associated protein 1 [IPR016897]", "S-phase kinase-associated protein 1-like [IPR001232]", "SAC3/GANP/THP3 [IPR045107]", "SAFB-like transcription modulator [IPR034780]", "SAP30-binding protein [IPR012479]", "SCAMP [IPR007273]", "SERRATE/Ars2 [IPR039727]", "SH3-binding, glutamic acid-rich protein [IPR006993]", "SKI-interacting protein, SKIP [IPR017862]", "SLC12A transporter family [IPR004842]", "SNF5/SMARCB1/INI1 [IPR006939]", "SNU66/SART1 family [IPR005011]", "SNX17/27/31 [IPR037831]", "SOUL haem-binding protein [IPR006917]", "SUMO-activating enzyme subunit Uba2 [IPR030661]", "SUN domain-containing protein 1 [IPR018539]", "SUN domain-containing protein 1-5 [IPR045119]", "SUN domain-containing protein 2 [IPR030272]", "SURP and G-patch domain-containing protein 1/2 [IPR040169]", "SWI/SNF complex subunit BAF57 [IPR030089]", "SWI/SNF complex subunit BRG1 [IPR030100]", "SWI/SNF complex subunit SMARCC1 [IPR030087]", "SWI/SNF complex subunit SMARCC2 [IPR038044]", "SWI/SNF-like complex subunit BAF250a [IPR030094]", "SWI/SNF-like complex subunit BAF250/Osa [IPR021906]", "Saposin [IPR008373]", "Saposin, chordata [IPR021165]", "Scaffold attachment factor B1 [IPR034781]", "Scaffold attachment factor B2 [IPR034782]", "Scavenger mRNA decapping enzyme DcpS/DCS2 [IPR008594]", "Schlafen family [IPR029684]", "Sec1-like protein [IPR001619]", "Sec13/Seh1 family [IPR037363]", "Sec20 [IPR005606]", "SecY/SEC61-alpha family [IPR002208]", "Sentrin-specific protease 3 [IPR037945]", "Sepiapterin reductase [IPR006393]", "Septin 2 [IPR008113]", "Septin 6 [IPR030644]", "Septin 7 [IPR008115]", "Septin 9 [IPR030645]", "Septin [IPR016491]", "Septin and tuftelin interacting protein [IPR024933]", "Serine hydroxymethyltransferase [IPR001085]", "Serine-tRNA ligase, type1 [IPR002317]", "Serine/arginine-rich splicing factor 10 [IPR034476]", "Serine/arginine-rich splicing factor 11 [IPR034447]", "Serine/arginine-rich splicing factor 6 [IPR029541]", "Serine/threonine protein phosphatase 5 [IPR011236]", "Serine/threonine-protein kinase OSR1 [IPR028749]", "Serine/threonine-protein kinase PAK2 [IPR035065]", "Serine/threonine-protein kinase RAC alpha [IPR039027]", "Serine/threonine-protein kinase TOR [IPR026683]", "Serine/threonine-protein phosphatase 2A subunit A, metazoa [IPR031090]", "Serine/threonine-protein phosphatase 4 regulatory subunit 1 [IPR031087]", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit [IPR037979]", "Serpin H1 [IPR033547]", "Serpin family [IPR000215]", "Shootin-1 [IPR024849]", "Short transmembrane mitochondrial protein 1 [IPR027854]", "Short-chain dehydrogenase/reductase SDR [IPR002347]", "Sideroflexin-4 [IPR028825]", "Sigma intracellular receptor 2 [IPR016964]", "Signal peptidase complex catalytic subunit SEC11A [IPR037712]", "Signal peptidase complex subunit 3 [IPR007653]", "Signal peptidase complex subunit Spc2/SPCS2 [IPR009582]", "Signal recognition particle SRP9 [IPR039914]", "Signal recognition particle receptor, beta subunit [IPR019009]", "Signal recognition particle subunit SRP68 [IPR026258]", "Signal recognition particle, SRP14 subunit [IPR003210]", "Signal recognition particle, SRP54 subunit [IPR022941]", "Signal recognition particle, SRP54 subunit, eukaryotic [IPR006325]", "Signal recognition particle, SRP72 subunit [IPR026270]", "Signal recognition particle, SRP9 subunit [IPR008832]", "Sin3 associated polypeptide p18 [IPR010516]", "Single-stranded DNA-binding protein [IPR011344]", "Sirtuin family [IPR003000]", "Sirtuin, class I [IPR017328]", "Sister chromatid cohesion protein Pds5 [IPR039776]", "Ski3/TTC37 [IPR039226]", "Sm-like protein Lsm6/SmF [IPR016487]", "Smac/DIABLO protein [IPR015142]", "Small (40S) ribosomal subunit Asc1/RACK1 [IPR045223]", "Small GTPase Rho [IPR003578]", "Small GTPase [IPR001806]", "Small GTPase superfamily, ARF type [IPR024156]", "Small GTPase superfamily, ARF/SAR type [IPR006689]", "Small GTPase superfamily, SAR1-type [IPR006687]", "Small GTPase, Ras-type [IPR020849]", "Small acidic protein [IPR026714]", "Small nuclear ribonucleoprotein E [IPR027078]", "Small nuclear ribonucleoprotein Sm D2 [IPR027248]", "Small nuclear ribonucleoprotein Sm D3 [IPR034099]", "Small-subunit processome, Utp11 [IPR007144]", "Small-subunit processome, Utp14 [IPR006709]", "Smooth muscle protein/calponin [IPR003096]", "Snf7 family [IPR005024]", "Sodium/potassium-transporting ATPase subunit beta [IPR000402]", "Sodium:dicarboxylate symporter [IPR001991]", "Solute carrier family 12 member 1/2 [IPR002443]", "Solute carrier family 12 member 2 [IPR002444]", "Solute carrier family 35 member SLC35F1/F2/F6 [IPR009262]", "Sorbitol dehydrogenase-like [IPR045306]", "Sorting nexin-1 [IPR028660]", "Sorting nexin-2 [IPR028653]", "Sorting nexin-27 [IPR028667]", "Sorting nexin-5 [IPR028654]", "Sorting nexin-5/6/32 [IPR014637]", "Sorting nexin-6 [IPR028657]", "Spartin-like [IPR045036]", "Spectrin, beta subunit [IPR016343]", "Spermatid perinuclear RNA-binding protein [IPR030446]", "Spermidine/spermine synthase, eukaryotes [IPR030668]", "Spermidine/spermine synthases [IPR001045]", "Spermine synthase, animal [IPR015576]", "Sphingomyelin phosphodiesterase 4 [IPR024129]", "Sphingosine N-acyltransferase Lag1/Lac1-like [IPR016439]", "Splicing factor 3A subunit 1 [IPR045146]", "Splicing factor 3A subunit 3 [IPR031776]", "Splicing factor 3B subunit 1-like [IPR038737]", "Splicing factor 3B subunit 5/RDS3 complex subunit 10 [IPR009846]", "Splicing factor 3B, subunit 5 [IPR017089]", "Splicing factor 45 [IPR040052]", "Splicing factor ELAV/Hu [IPR006548]", "Splicing factor, RBM39-like [IPR006509]", "Splicing factor, arginine/serine-rich 19 [IPR042841]", "Squalene cyclase [IPR018333]", "Squalene monooxygenase [IPR040125]", "Squalene synthase-like [IPR006449]", "Squalene/phytoene synthase [IPR002060]", "Stathmin family [IPR000956]", "Steroidogenic acute regulatory protein-like [IPR000799]", "Sterol O-acyltransferase, ACAT/DAG/ARE types [IPR014371]", "Sterol O-acyltransferase, metazoa [IPR030687]", "Stomatin/HflK/HflC family [IPR001972]", "Stromal interaction molecule [IPR037608]", "Structural maintenance of chromosomes flexible hinge domain-containing protein 1 [IPR038892]", "Structural maintenance of chromosomes protein 1A, metazoan [IPR029683]", "Structural maintenance of chromosomes protein 5 [IPR027131]", "Structural maintenance of chromosomes protein [IPR024704]", "Structure-specific recognition protein [IPR000969]", "Succinate dehydrogenase, flavoprotein subunit [IPR011281]", "Succinate dehydrogenase/fumarate reductase iron-sulphur protein [IPR004489]", "Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [IPR014006]", "Succinate semialdehyde dehydrogenase [IPR010102]", "Succinate--CoA synthetase, beta subunit [IPR005809]", "Succinyl-CoA ligase, alpha subunit [IPR005810]", "Sulfhydryl oxidase [IPR039798]", "Sulfotransferase [IPR005331]", "Sulfurtransferase TST/MPST-like [IPR045078]", "Suppressor of white apricot [IPR040397]", "Surface antigen D15-like [IPR039910]", "Surfeit locus 1/4 [IPR045214]", "Surfeit locus 4 [IPR002995]", "Surfeit locus 6 [IPR007019]", "Symplekin/Pta1 [IPR021850]", "Synaptic vesicle protein SV2 [IPR022308]", "Synaptobrevin [IPR001388]", "Synaptogyrin [IPR016579]", "Syntaxin [IPR045242]", "Syntaxin-17 [IPR028676]", "Syntenin-1 [IPR030528]", "Synthesis of cytochrome c oxidase, Sco1/Sco2 [IPR017276]", "T-complex protein 1, alpha subunit [IPR012715]", "T-complex protein 1, beta subunit [IPR012716]", "T-complex protein 1, delta subunit [IPR012717]", "T-complex protein 1, epsilon subunit [IPR012718]", "T-complex protein 1, eta subunit [IPR012720]", "T-complex protein 1, gamma subunit [IPR012719]", "T-complex protein 1, theta subunit [IPR012721]", "T-complex protein 1, zeta subunit [IPR012722]", "TACC family [IPR039915]", "TAF15/EWS/TLS family [IPR034870]", "TAP46-like protein [IPR007304]", "TATA binding associated factor 15 [IPR034875]", "TB2/DP1/HVA22-related protein [IPR004345]", "TCF25/Rqc1 [IPR006994]", "TE2IP/Rap1 [IPR039595]", "TEL2-interacting protein 1 [IPR016441]", "TFP11/STIP/Ntr1 [IPR045211]", "TH1 protein [IPR006942]", "THO complex, subunit THOC1 [IPR021861]", "THRAP3/BCLAF1 family [IPR029199]", "THUMP domain-containing protein 1-like [IPR040183]", "TMEM14 family [IPR005349]", "TMEM192 family [IPR029399]", "TMEM33/Pom33 family [IPR005344]", "TMEM85/ER membrane protein complex subunit 4 [IPR009445]", "TOX high mobility group box family member 4 [IPR037985]", "TPP-binding domain containing protein HACL1-like [IPR045025]", "TPX2 [IPR009675]", "TRAPP I complex, subunit 5 [IPR016696]", "TREX component Tex1/THOC3 [IPR040132]", "TatSF1-like [IPR034393]", "Taxilin family [IPR026183]", "Telomere-associated protein Rif1 [IPR028566]", "Testin [IPR027683]", "Testis-expressed protein 10/pre-rRNA-processing protein Ipi1 [IPR037947]", "Tetrahydrofolate dehydrogenase/cyclohydrolase [IPR000672]", "Tetraspanin, animals [IPR000301]", "Tetraspanin/Peripherin [IPR018499]", "Tetratricopeptide repeat protein 19 [IPR040395]", "Tetratricopeptide repeat protein 26 [IPR030511]", "Tetratricopeptide repeat protein 38 [IPR033891]", "ThiF/MoeB/HesA family [IPR045886]", "Thiamine pyrophosphate enzyme [IPR045229]", "Thiolase [IPR002155]", "Thioredoxin domain-containing protein 17-like [IPR045108]", "Thioredoxin-related transmembrane protein 2 [IPR039101]", "Thioredoxin/glutathione reductase selenoprotein [IPR006338]", "Threonine-tRNA ligase, class IIa [IPR002320]", "Thymidine kinase [IPR001267]", "Thymidylate kinase [IPR018094]", "Thymidylate synthase [IPR000398]", "Thymidylate synthase/dCMP hydroxymethylase [IPR045097]", "Thyroid hormone receptor-associated protein 3 [IPR026667]", "Tight junction protein ZO [IPR005417]", "Tight junction protein ZO-1 [IPR005418]", "Tim23-like [IPR045238]", "Tim44-like [IPR039544]", "Timeless [IPR044998]", "TmcA/NAT10/Kre33 [IPR032672]", "Tom40 [IPR037930]", "Torsin-1A-interacting protein 1/2 [IPR008662]", "TraB/PrgY/GumN family [IPR002816]", "Trafficking protein particle complex subunit [IPR007233]", "Trans-isoprenyl diphosphate synthases, eukaryotic-type [IPR044844]", "Transaldolase type 1 [IPR004730]", "Transaldolase/Fructose-6-phosphate aldolase [IPR001585]", "Transcription elongation factor SPT5 [IPR039659]", "Transcription elongation factor Spt5, eukaryote [IPR017071]", "Transcription elongation factor Spt6 [IPR017072]", "Transcription elongation factor, IIS-type [IPR035100]", "Transcription elongation factor, TFIIS [IPR006289]", "Transcription elongation regulator 1-like [IPR045148]", "Transcription facto Tfc3-like [IPR044210]", "Transcription factor BTF3 [IPR039370]", "Transcription factor E [IPR039997]", "Transcription factor II-I [IPR016659]", "Transcription factor IIIC subunit Tfc1/Sfc1 [IPR040454]", "Transcription factor STAT [IPR001217]", "Transcription factor Tfc4/TFIIIC-102/Sfc4 [IPR039340]", "Transcription factor, enhancer of yellow 2 [IPR018783]", "Transcription intermediary factor 1-beta [IPR037373]", "Transcriptional regulator TACO1-like [IPR002876]", "Transcriptional regulatory protein Sin3-like [IPR039774]", "Transcriptional regulatory protein Sin3a [IPR037969]", "Transcriptional repressor p66 [IPR040386]", "Transducin beta-like protein 2 [IPR042410]", "Transferrin receptor protein 1 [IPR029513]", "Transgelin-2 [IPR001061]", "Translation Initiation factor eIF- 4e [IPR001040]", "Translation elongation factor EF1A, eukaryotic/archaeal [IPR004539]", "Translation elongation factor EFG/EF2 [IPR004540]", "Translation elongation factor EFTs/EF1B [IPR001816]", "Translation elongation factor EFTu/EF1A, bacterial/organelle [IPR004541]", "Translation elongation factor IF5A-like [IPR001884]", "Translation initiation factor 2, alpha subunit [IPR011488]", "Translation initiation factor 2A [IPR011387]", "Translation initiation factor 3 complex subunit L [IPR019382]", "Translation initiation factor IF- 2 [IPR015760]", "Translation initiation factor IF2/IF5 [IPR045196]", "Translation initiation factor IF6 [IPR002769]", "Translation initiation factor aIF-2, bacterial-like [IPR000178]", "Translation machinery-associated protein 16 [IPR021346]", "Translational activator Gcn1 [IPR033173]", "Translationally controlled tumour protein [IPR018105]", "Translin [IPR033956]", "Translin family [IPR002848]", "Translocation associated membrane protein [IPR016447]", "Translocation protein Sec63 [IPR027137]", "Translocon-associated [IPR008855]", "Translocon-associated protein (TRAP), alpha subunit [IPR005595]", "Transmembrane emp24 domain-containing protein 7 [IPR015718]", "Transmembrane emp24 domain-containing protein [IPR015720]", "Transmembrane protein 109 [IPR039492]", "Transmembrane protein 11 [IPR026120]", "Transmembrane protein 126 [IPR009801]", "Transmembrane protein 160 [IPR026801]", "Transmembrane protein 205 [IPR042623]", "Transmembrane protein 214 [IPR019308]", "Transmembrane protein 230 [IPR044234]", "Transmembrane protein 230/134 [IPR008590]", "Transmembrane protein 43 family [IPR012430]", "Transmembrane protein 65 [IPR019537]", "Transmembrane protein GPR107/GPR108-like [IPR009637]", "Transport protein particle (TRAPP) component [IPR007194]", "Treacle protein [IPR017859]", "Tricarboxylate/iron carrier [IPR004686]", "Triosephosphate isomerase [IPR000652]", "Triosephosphate isomerase, bacterial/eukaryotic [IPR022896]", "Trm112-like [IPR005651]", "Tropomodulin [IPR004934]", "Tropomodulin-3 [IPR030133]", "Tropomyosin [IPR000533]", "Tryptophan-tRNA ligase [IPR002306]", "Tuberin [IPR003913]", "Tuberin/Ral GTPase-activating protein subunit alpha [IPR027107]", "Tubulin [IPR000217]", "Tubulin binding cofactor A [IPR004226]", "Tubulin--tyrosine ligase-like protein 12 [IPR027749]", "Tubulin-folding cofactor D [IPR033162]", "Tubulin-specific chaperone E [IPR044994]", "Tubulin-tyrosine ligase/Tubulin polyglutamylase [IPR004344]", "Tumour protein D52 [IPR007327]", "Tweety [IPR006990]", "Twinfilin [IPR028458]", "Twinkle-like protein [IPR027032]", "Type 1 protein exporter [IPR039421]", "Type II pantothenate kinase [IPR004567]", "Type II phosphatidylinositol 4-kinase Lsb6/PI4K2 [IPR039756]", "Tyrosine-protein kinase, insulin-like receptor [IPR016246]", "Tyrosine-tRNA ligase [IPR002307]", "Tyrosine-tRNA ligase, bacterial-type [IPR024088]", "Tyrosine/threonine-protein kinase, Cdc2 inhibitor [IPR016235]", "U2 auxiliary factor small subunit [IPR009145]", "U2 small nuclear ribonucleoprotein A' [IPR044640]", "U2 snRNP auxilliary factor, large subunit, splicing factor [IPR006529]", "U3 small nucleolar RNA-associated protein 10 [IPR040191]", "U3 small nucleolar RNA-associated protein 18 [IPR045161]", "U3 small nucleolar RNA-associated protein 25 [IPR010678]", "U3 small nucleolar RNA-associated protein 6 [IPR013949]", "U3 small nucleolar ribonucleoprotein complex, subunit Mpp10 [IPR012173]", "U4/U6 small nuclear ribonucleoprotein Prp3 [IPR027104]", "U4/U6 small nuclear ribonucleoprotein Prp31 [IPR027105]", "U6 snRNA-associated Sm-like protein LSm2 [IPR016654]", "UAA transporter [IPR013657]", "UBAP2/protein lingerer [IPR022166]", "UDP-N-acetylglucosamine 2-epimerase,UDP-hydrolysing [IPR020004]", "UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110kDa subunit [IPR037919]", "UDP-glucose 6-dehydrogenase, eukaryotic type [IPR028356]", "UDP-glucose/GDP-mannose dehydrogenase [IPR017476]", "UDP-glucose:Glycoprotein Glucosyltransferase [IPR009448]", "UDP-sugar pyrophosphorylase [IPR039741]", "UDPGP family [IPR002618]", "UHRF1/2-like [IPR045134]", "UMP-CMP kinase [IPR006266]", "USP39 [IPR033809]", "UTP--glucose-1-phosphate uridylyltransferase [IPR016267]", "UV excision repair protein Rad23 [IPR004806]", "Ubiquinol-cytochrome c chaperone, CBP3 [IPR007129]", "Ubiquinol-cytochrome c chaperone/UPF0174 [IPR021150]", "Ubiquitin binding protein, Hrs/VPS27 [IPR017073]", "Ubiquitin carboxyl-terminal hydrolase 10 [IPR028767]", "Ubiquitin carboxyl-terminal hydrolase 14-like [IPR044635]", "Ubiquitin conjugation factor E4 [IPR045132]", "Ubiquitin fusion degradation protein Ufd1-like [IPR004854]", "Ubiquitin thioesterase OTUB1 [IPR030298]", "Ubiquitin thioesterase Otubain [IPR016615]", "Ubiquitin thioesterase otulin [IPR023237]", "Ubiquitin-activating enzyme E1 [IPR018075]", "Ubiquitin-fold modifier-conjugating enzyme 1 [IPR014806]", "Ubiquitin-like-conjugating enzyme Atg3/Atg10 [IPR007135]", "Ubiquitin-protein ligase E3B/C [IPR044611]", "Ubiquitin/SUMO-activating enzyme E1 [IPR000011]", "Ubiquitinyl hydrolase [IPR016652]", "Ubiquitinyl hydrolase, UCH37 type [IPR017390]", "Uncharacterised conserved protein UCP013899, metal binding [IPR016617]", "Uncharacterised protein family UPF0449 [IPR028227]", "Uncharacterised protein family UPF0687 [IPR026794]", "Uracil-DNA glycosylase family 1 [IPR002043]", "Uridine kinase-like [IPR000764]", "Uridine-cytidine kinase 2 [IPR029925]", "Uroporphyrinogen decarboxylase HemE [IPR006361]", "V-type ATPase, V0 complex, 116kDa subunit family [IPR002490]", "V-type ATP synthase catalytic alpha chain [IPR022878]", "V-type ATP synthase regulatory subunit B/beta [IPR022879]", "V-type ATPase subunit E [IPR002842]", "V0 complex accessory subunit Ac45 [IPR008388]", "Vacuolar protein sorting protein 26 related [IPR028934]", "Vacuolar protein sorting-associated protein 13 [IPR026847]", "Vacuolar protein sorting-associated protein 29 [IPR028661]", "Vacuolar protein sorting-associated protein 33 [IPR027121]", "Vacuolar protein sorting-associated protein 35 [IPR005378]", "Vacuolar protein sorting-associated protein 4 [IPR031255]", "Vacuolar protein sorting-associated protein 51 [IPR014812]", "Vacuolar protein sorting-associated protein 53 [IPR039766]", "Vacuolar protein sorting-associated protein 9-like [IPR045046]", "Vacuolar protein sorting-associated protein Ist1 [IPR005061]", "Vacuolar protein-sorting protein Bro1-like [IPR045251]", "Vacuole morphology and inheritance protein 14 [IPR026825]", "Valine-tRNA ligase [IPR002303]", "Vesicle-associated membrane-protein-associated protein [IPR016763]", "Vesicle-fusing ATPase [IPR039812]", "Vesicle-trafficking protein Sec22 [IPR044565]", "Vezatin [IPR026858]", "Villin/Gelsolin [IPR007122]", "Vimentin [IPR027699]", "Vinculin [IPR017997]", "Vinculin/alpha-catenin [IPR006077]", "Vitamin K-dependent gamma-carboxylase [IPR007782]", "Voltage-dependent anion-selective channel protein 1 [IPR030270]", "Voltage-dependent anion-selective channel protein 2 [IPR030277]", "Voltage-dependent anion-selective channel protein 3 [IPR030271]", "WD repeat BOP1/Erb1 [IPR028598]", "WD repeat Prp46/PLRG1-like [IPR045241]", "WD repeat domain phosphoinositide-interacting protein 2 [IPR032911]", "WD repeat-containing protein 41 [IPR040102]", "WD repeat-containing protein 73 [IPR042795]", "WD repeat-containing protein DCAF7-like [IPR045159]", "WD repeat-containing protein WDR18/Ipi3/RID3 [IPR045227]", "WD repeat-containing protein WDR46/Utp7 [IPR040315]", "WD40 repeat-containing protein SMU1 [IPR045184]", "WW domain binding protein 11 [IPR019007]", "WW domain-binding protein 2 [IPR033598]", "WW domain-binding protein 2-like [IPR044852]", "Wings apart-like protein [IPR039874]", "Wolframin [IPR026208]", "Wolframin family [IPR026209]", "XMAP215 family [IPR045110]", "XPG/Rad2 endonuclease [IPR006084]", "Xaa-Arg dipeptidase [IPR017144]", "YAP-binding/ALF4/Glomulin [IPR013877]", "YTH domain containing protein [IPR045168]", "YgfZ/GcvT [IPR045179]", "YjeF N-terminal domain-containing protein NAXE-like [IPR032976]", "YjgF/YER057c/UK114 family [IPR006175]", "ZPR1 family [IPR040141]", "Zinc finger CCHC domain-containing protein 3 [IPR042509]", "Zinc finger FYVE domain containing protein, SARA/endofin [IPR035438]", "Zinc finger FYVE domain-containing protein, endofin [IPR017165]", "Zinc finger Ran-binding domain-containing protein 2 [IPR017337]", "Zinc finger protein 532-like [IPR045914]", "Zinc finger protein 622/Rei1/Reh1 [IPR040025]", "Zinc finger protein 638 [IPR033096]", "Zinc transporter Msc2-like [IPR045316]", "cAMP-dependent protein kinase catalytic subunit [IPR044109]", "cAMP-dependent protein kinase regulatory subunit [IPR012198]", "dCTP pyrophosphatase 1 [IPR025984]", "dTDP-4-dehydrorhamnose reductase family [IPR005913]", "hnRNP A2/B1 [IPR034489]", "mRNA 3'-end-processing protein Rna14-like [IPR045243]", "mRNA cap guanine-N7 methyltransferase [IPR039753]", "mRNA cap guanine-N7 methyltransferase, eukaryotes [IPR016899]", "mRNA export factor Gle2/RAE1 [IPR037631]", "p53 tumour suppressor family [IPR002117]", "rRNA biogenesis protein Rrp5 [IPR045209]", "tRNA (C5-cytosine) methyltransferase, NCL1 [IPR023270]", "tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 [IPR017423]", "tRNA (cytidine(32)/guanosine(34)-2-O)-methyltransferase, Trm7 [IPR028590]", "tRNA (guanine-N-7) methyltransferase catalytic subunit Trm8, eukaryote [IPR025763]", "tRNA (guanine-N-7) methyltransferase, Trmb type [IPR003358]", "tRNA (guanine-N1-)-methyltransferase, eukaryotic [IPR007356]", "tRNA (uracil(54)-C(5))-methyltransferase, eukaryotic type [IPR045850]", "tRNA N6-adenosine threonylcarbamoyltransferase Kae1, archaea and eukaryote [IPR034680]", "tRNA guanosine-2'-O-methyltransferase, TRM11 [IPR016691]", "tRNA methyltransferase 10 homologue C [IPR025812]", "tRNA pseudouridine synthase B family [IPR004802]", "tRNA pseudouridine synthase II, TruB [IPR014780]"], "available_proteins": ["AAAS", "AAR2", "AARS", "AARS2", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABHD12", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACADM", "ACAP2", "ACAT1", "ACAT2", "ACLY", "ACO2", "ACOT13", "ACOT7", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL6", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADD1", "ADH5", "ADI1", "ADK", "ADNP", "ADO", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFG3L2", "AGL", "AGPS", "AHCY", "AHCYL1", "AHSA1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP12", "AKAP17A", "AKAP8", "AKR1A1", "AKR1B1", "AKT1", "AKT1S1", "ALDH18A1", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALKBH5", "AMOT", "ANAPC16", "ANAPC5", "ANKLE2", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP3B1", "AP3D1", "AP3M1", "APEX1", "API5", "APOL2", "APOOL", "APRT", "AQR", "ARCN1", "ARF4", "ARFIP1", "ARFIP2", "ARHGAP5", "ARHGDIA", "ARID1A", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL6IP4", "ARL6IP5", "ARL8B", "ARMC1", "ARMC6", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "AS3MT", "ASAH1", "ASNA1", "ASNS", "ASPH", "ASPM", "ASRGL1", "ATAD3A", "ATAD3B", "ATG3", "ATG4B", "ATIC", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7B", "ATPAF1", "ATPIF1", "ATXN2L", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAIAP2", "BAK1", "BANF1", "BAP18", "BASP1", "BAX", "BCAP31", "BCAS2", "BCAT2", "BCCIP", "BCL10", "BCL2L13", "BCLAF1", "BET1", "BIRC6", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOP1", "BPNT1", "BRI3BP", "BRIX1", "BSG", "BTF3", "BUD31", "BYSL", "C11orf58", "C12orf43", "C12orf73", "C15orf39", "C19orf25", "C19orf70", "C1QBP", "C1orf123", "C1orf35", "C20orf27", "C21orf59", "C2CD2", "C2CD5", "C2orf49", "C5orf15", "CAB39", "CACUL1", "CAD", "CALD1", "CALR", "CALU", "CAND1", "CANX", "CAP1", "CAPN1", "CAPRIN1", "CAPZA1", "CAPZB", "CARM1", "CARS", "CARS2", "CASP2", "CASP3", "CASP6", "CAST", "CBFB", "CBR1", "CBX3", "CCAR1", "CCAR2", "CCDC124", "CCDC47", "CCDC6", "CCDC86", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD47", "CD81", "CDC123", "CDC37", "CDC42", "CDC45", "CDC73", "CDCA8", "CDK5RAP3", "CDK6", "CDKAL1", "CDS2", "CDV3", "CEBPZ", "CELF2", "CEP170", "CEP44", "CEP55", "CERS2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1L", "CHERP", "CHMP2A", "CHMP5", "CHMP7", "CHORDC1", "CHST14", "CIAPIN1", "CIP2A", "CISD2", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLP1", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTA", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNOT1", "CNOT11", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG7", "COIL", "COLGALT1", "COMMD10", "COMMD2", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "CORO1C", "COTL1", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF2", "CPSF6", "CPSF7", "CPT2", "CPVL", "CRNKL1", "CRTAP", "CRYZL1", "CS", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWF19L1", "CXorf57", "CYB5R3", "CYC1", "CYFIP1", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAXX", "DBN1", "DBNL", "DCAF7", "DCAKD", "DCD", "DCPS", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCXR", "DDA1", "DDB1", "DDOST", "DDRGK1", "DDX54", "DEK", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHFR", "DHPS", "DHRS7", "DHRS7B", "DHX29", "DIABLO", "DIAPH1", "DIAPH3", "DIDO1", "DIEXF", "DIS3L2", "DKC1", "DLAT", "DLD", "DLST", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJC10", "DNAJC8", "DNM1", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOHH", "DPH2", "DPM1", "DPP3", "DPYSL2", "DPYSL3", "DRG1", "DRG2", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC4", "EEF1A2", "EEF1E1", "EEF1G", "EFCAB14", "EHD1", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2B1", "EIF2B2", "EIF2B4", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "ENDOD1", "ENO1", "ENOPH1", "ENSA", "ENY2", "EPB41", "EPB41L2", "EPB41L3", "EPHX1", "EPHX2", "EPPK1", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERC1", "ERCC2", "ERGIC3", "ERH", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ESD", "ESS2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC2", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EYA3", "EZR", "F11R", "FABP5", "FADS2", "FAH", "FAM114A2", "FAM120A", "FAM120B", "FAM136A", "FAM162A", "FAM177A1", "FAM3C", "FAM49B", "FAM8A1", "FAM91A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FAU", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FLCN", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNTB", "FOXC1", "FRG1", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GALK1", "GALM", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GBA", "GCAT", "GCFC2", "GCLM", "GCN1", "GDI1", "GDI2", "GEMIN4", "GET4", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GHITM", "GINS1", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GM2A", "GMFB", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNPDA1", "GNS", "GOLGA3", "GOLGB1", "GOLIM4", "GOPC", "GOT1", "GOT2", "GPAA1", "GPD2", "GPI", "GPKOW", "GPR107", "GPR108", "GPS1", "GPT2", "GRIPAP1", "GRPEL1", "GRSF1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2E1", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP4", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS4", "HAUS5", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDHD2", "HDHD3", "HDHD5", "HEATR1", "HEBP1", "HECTD1", "HELZ", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLCS", "HM13", "HMGA1", "HMGB1", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPC", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HP1BP3", "HPRT1", "HPS6", "HS1BP3", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IGBP1", "IGF1R", "IGF2BP2", "IK", "IKBIP", "ILF3", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPAD1", "IMPDH2", "INA", "INCENP", "INF2", "INTS3", "INTS9", "IPO4", "IPO5", "IRS4", "ISCU", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPK1", "IVD", "JPT2", "JUP", "KARS", "KDELR1", "KDM1A", "KDM3B", "KDSR", "KHDRBS1", "KIAA0368", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF5B", "KIFBP", "KLC1", "KLC2", "KLC4", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "LAMP1", "LAMTOR1", "LAMTOR2", "LANCL1", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDAH", "LDHA", "LDHB", "LEMD3", "LENG8", "LETM1", "LGALS3", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LNPEP", "LONP1", "LRPAP1", "LRPPRC", "LRRC47", "LSG1", "LSM12", "LSM2", "LSM6", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LZTFL1", "LZTS2", "M6PR", "MACF1", "MAGED2", "MAK16", "MANF", "MAP1B", "MAP1S", "MAP3K7", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCKS", "MARCKSL1", "MARS", "MAT2A", "MAT2B", "MAU2", "MAVS", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED17", "MED24", "MED25", "MEPCE", "MESD", "METTL1", "MFF", "MFN2", "MFSD10", "MFSD5", "MGEA5", "MGST2", "MGST3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MIPEP", "MLEC", "MMAB", "MMGT1", "MMS19", "MOGS", "MORF4L1", "MORF4L2", "MOV10", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPST", "MPV17L2", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL40", "MRPL44", "MRPL46", "MRPL50", "MRPL9", "MRPS10", "MRPS15", "MRPS17", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSN", "MTA1", "MTA2", "MTAP", "MTBP", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR6", "MTOR", "MTX1", "MTX2", "MTX3", "MVD", "MVK", "MXRA7", "MYBBP1A", "MYDGF", "MYEF2", "MYG1", "NAA10", "NAA15", "NAA25", "NAA35", "NAA40", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCAPH2", "NCBP1", "NCDN", "NCK1", "NCKAP1", "NCLN", "NCSTN", "NDC1", "NDRG3", "NDUFA13", "NDUFA4", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB4", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NEFL", "NEFM", "NELFB", "NELFCD", "NELFE", "NES", "NFS1", "NHP2", "NIP7", "NIPA2", "NLN", "NME1", "NME2", "NMT1", "NNT", "NOC2L", "NOC3L", "NOC4L", "NOL11", "NOL6", "NOL7", "NOL9", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOSIP", "NOVA2", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NSA2", "NSF", "NSL1", "NSMCE2", "NSUN2", "NSUN5", "NSUN6", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDT1", "NUDT21", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUTF2", "NXF1", "OAT", "OCIAD1", "ODR4", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC3", "OSBP", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTULIN", "OXA1L", "OXSR1", "P3H1", "P4HA1", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAK2", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PATL1", "PBDC1", "PBRM1", "PC", "PCBD1", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6IP", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDS5A", "PDS5B", "PDXDC1", "PDXK", "PEBP1", "PECR", "PES1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PHAX", "PHB", "PHB2", "PHF5A", "PHGDH", "PHIP", "PI4K2A", "PICALM", "PIGK", "PIGS", "PIGU", "PIK3C2A", "PIN4", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PKM", "PKMYT1", "PLA2G15", "PLBD2", "PLCG1", "PLEC", "PLIN3", "PLRG1", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PMVK", "PNN", "PNO1", "PNP", "PNPO", "PNPT1", "POFUT1", "POLA1", "POLA2", "POLD1", "POLE", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPHLN1", "PPIH", "PPIL1", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP2R1A", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4R1", "PPP5C", "PPT1", "PPT2", "PRAF2", "PRC1", "PRCP", "PRDX2", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCSH", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF40A", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PTBP1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPA", "PTPN1", "PTPN11", "PTRH2", "PUF60", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXN", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB21", "RAB24", "RAB34", "RAB35", "RAB39A", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB8B", "RABGAP1", "RABGGTA", "RAC1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD51AP1", "RAE1", "RAI14", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RAP1GDS1", "RAPGEF2", "RARS", "RASA1", "RAVER1", "RBBP5", "RBBP6", "RBM10", "RBM17", "RBM26", "RBM27", "RBM39", "RBM8A", "RBP1", "RCC2", "RCL1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "REEP5", "RER1", "RETREG3", "REXO2", "REXO4", "RFC1", "RFLNB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RINT1", "RNASEH2A", "RNASEH2B", "RNASET2", "RNF14", "RNF40", "RNMT", "RNPEP", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSBN1", "RSF1", "RSL1D1", "RTCB", "RTFDC1", "RTN4IP1", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SAE1", "SAFB", "SAFB2", "SAMM50", "SAP18", "SAP30BP", "SAR1A", "SARS", "SARS2", "SART1", "SBDS", "SCAF1", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCD", "SCFD1", "SCO1", "SCO2", "SCPEP1", "SCRN1", "SDCBP", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC31A", "SEC61A1", "SEC61B", "SEC63", "SEH1L", "SENP3", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD7", "SF1", "SF3A1", "SF3A3", "SF3B1", "SF3B5", "SFSWAP", "SFXN1", "SFXN4", "SGPL1", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIN3A", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC30A5", "SLC35A4", "SLC35B2", "SLC35F2", "SLC3A2", "SLC9A3R1", "SLFN11", "SLK", "SLTM", "SMARCA4", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMCHD1", "SMPD4", "SMS", "SMU1", "SMYD3", "SND1", "SNRPA1", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SNX27", "SNX5", "SNX6", "SOAT1", "SOD2", "SON", "SORD", "SPAG9", "SPART", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPECC1L", "SPOUT1", "SPPL2A", "SPR", "SPTBN1", "SPTBN2", "SQLE", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPRB", "SRRT", "SRSF10", "SRSF11", "SRSF6", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "STAG2", "STARD3", "STAT1", "STAT3", "STIM2", "STIP1", "STMN1", "STOML2", "STRBP", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX17", "STX4", "STX5", "STX7", "STX8", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SURF4", "SURF6", "SV2A", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "TAB1", "TACC3", "TACO1", "TAF15", "TAGLN2", "TALDO1", "TAMM41", "TARS", "TARS2", "TBCA", "TBCD", "TBCE", "TBL2", "TCEA1", "TCERG1", "TCF25", "TCOF1", "TCP1", "TECR", "TERF2IP", "TES", "TEX10", "TFG", "TFIP11", "TFRC", "THOC1", "THOC3", "THOP1", "THRAP3", "THUMPD1", "TIMELESS", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TK1", "TM9SF2", "TM9SF3", "TMA16", "TMCO1", "TMED10", "TMED2", "TMED7", "TMEM109", "TMEM11", "TMEM126A", "TMEM14C", "TMEM160", "TMEM192", "TMEM199", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM33", "TMEM43", "TMEM65", "TMEM87A", "TMEM97", "TMOD3", "TMX2", "TNPO1", "TNPO2", "TOE1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOP1", "TOP2A", "TOP2B", "TOR1AIP1", "TOR1AIP2", "TOX4", "TP53", "TPD52", "TPD52L2", "TPI1", "TPM3", "TPM4", "TPP2", "TPT1", "TPX2", "TRABD", "TRAM1", "TRAP1", "TRAPPC4", "TRAPPC5", "TRIM28", "TRIP12", "TRIP13", "TRMT10C", "TRMT11", "TRMT112", "TRMT2A", "TRMT6", "TROVE2", "TRUB1", "TSC2", "TSFM", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPYL1", "TSR1", "TSTA3", "TTC19", "TTC26", "TTC37", "TTC38", "TTI1", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC9", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBAP2L", "UBE3C", "UBE4A", "UBR4", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UFSP2", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119", "UNG", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCR10", "UQCRB", "UQCRFS1", "UQCRQ", "URB1", "UROD", "USMG5", "USP10", "USP14", "USP39", "USP5", "USP9X", "UTP11", "UTP14A", "UTP18", "UTP6", "UTRN", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VPS13A", "VPS26A", "VPS29", "VPS33A", "VPS35", "VPS4A", "VPS51", "VPS53", "WAPL", "WARS", "WBP11", "WBP2", "WDR18", "WDR33", "WDR41", "WDR46", "WDR73", "WDR82", "WFS1", "WIPI2", "WTAP", "XAB2", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YME1L1", "YTHDC1", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZC3H14", "ZCCHC3", "ZDHHC13", "ZFYVE16", "ZMPSTE24", "ZNF326", "ZNF598", "ZNF622", "ZNF638", "ZNF687", "ZPR1", "ZRANB2", "ZW10"], "leading_proteins": ["ABCB7", "ACAT1", "ACOX3", "ARF4", "ARFIP2", "ARL1", "ARL6IP5", "CASP3", "CHMP7", "CLGN", "CLIC4", "CLPTM1L", "COASY", "COPS4", "CUL1", "CUL2", "CUL3", "CUL5", "CYP20A1", "DNAJA2", "EIF4G1", "EIF4G3", "H1F0", "H1FX", "H2AFY2", "HADHB", "HIST1H1C", "HIST1H1E", "HMOX2", "HSP90AB1", "IDH3B", "IDH3G", "ILKAP", "IPO4", "IPO5", "KIF1A", "KIF23", "KIF2A", "LANCL1", "LDHB", "LRRC47", "MARCKSL1", "MDH1", "MDH2", "MIPEP", "MRPL3", "MRPS5", "MSN", "MTA1", "MTIF2", "MTX1", "NSA2", "NUP214", "PDIA4", "PFDN5", "PHB2", "PLS1", "POLR1A", "PPM1F", "PRDX2", "PRKAR1A", "PRRC2A", "PSMB2", "PSMC1", "PSMC4", "PSMC6", "PYGL", "RBP1", "RPL7", "RUVBL1", "SAE1", "SAR1A", "SARS", "SCO1", "SEPT6", "SEPT9", "SERPINH1", "SHMT2", "SLC25A32", "SMC1A", "SMC2", "SMC4", "STT3B", "TARS2", "TIMM13", "TIMM17B", "TMEM87A", "TNPO1", "TNPO2", "TOR1AIP1", "TPD52", "TRAP1", "TSN", "TUBB2A", "TUBB4A", "TUBB4B", "TUBGCP3", "TWF2", "UBA1", "VAMP7", "VAPB", "YARS", "YARS2"]} \ No newline at end of file diff --git a/interpro_homologous_superfamily/advanced/idx2term.json b/interpro_homologous_superfamily/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_homologous_superfamily/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_homologous_superfamily/basic/idx2term.json b/interpro_homologous_superfamily/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..610abcd6632156d17dbbe1455033b5aa88e1c472 --- /dev/null +++ b/interpro_homologous_superfamily/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "PH-like domain superfamily [IPR011993]", "1": "S-adenosyl-L-methionine-dependent methyltransferase [IPR029063]", "2": "Protein kinase-like domain superfamily [IPR011009]", "3": "Ankyrin repeat-containing domain superfamily [IPR036770]", "4": "K Homology domain, type 1 superfamily [IPR036612]", "5": "Homeobox-like domain superfamily [IPR009057]", "6": "SNF2-like, N-terminal domain superfamily [IPR038718]", "7": "Winged helix DNA-binding domain superfamily [IPR036390]", "8": "Armadillo-like helical [IPR011989]", "9": "Winged helix-like DNA-binding domain superfamily [IPR036388]", "10": "EF-hand domain pair [IPR011992]", "11": "Histidine kinase/HSP90-like ATPase superfamily [IPR036890]", "12": "Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily [IPR018163]"} \ No newline at end of file diff --git a/interpro_homologous_superfamily/basic/plot_0.png b/interpro_homologous_superfamily/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..dbce2fd0f98d48a9c1ff27a295158327b2903a14 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9022e68c4cb9fd305ffdf1183664b7c6ebf6ddc9dcffb3edc385c2916d70162d +size 136602 diff --git a/interpro_homologous_superfamily/basic/plot_1.png b/interpro_homologous_superfamily/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..f82c8970d0f3ebbe585c56920b7f9541a7607000 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ad5e4cd973661e9fa7703235c1efaff38d954e3c38a2d76d34aabe0743fc879f +size 148748 diff --git a/interpro_homologous_superfamily/basic/plot_10.png b/interpro_homologous_superfamily/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..17551654f1fbeb7409e3c5ae8a2ced0608839997 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0d86dda264de60957d79f7d103389525beb91986315fc41c69bc10b58ac876e9 +size 141846 diff --git a/interpro_homologous_superfamily/basic/plot_11.png b/interpro_homologous_superfamily/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..13255ed019ddd31a45121a9a5cc5b5ffd88af33d --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ce034e0386ed649ae6047be93939ebb6b701f12efc11d3988048f42f3bb6e6ed +size 152350 diff --git a/interpro_homologous_superfamily/basic/plot_12.png b/interpro_homologous_superfamily/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..8ad8f1e0cf7bf8301228b2f1a2a42dea5fab4231 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1283a057753b84ba5eb67e3e0526d13aaede7724891aaa4c2e14f19dae2d51c7 +size 150488 diff --git a/interpro_homologous_superfamily/basic/plot_2.png b/interpro_homologous_superfamily/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..d9ccade455500bb6491f52f673cdc958520c229d --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0bc5668d4408270b72655b84eddaf7655171afff3fa5543ef55b62e967d06780 +size 143249 diff --git a/interpro_homologous_superfamily/basic/plot_3.png b/interpro_homologous_superfamily/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..0d2ef57b1061d230b5c3ee4437281441c692b903 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:14e622fe75e33055c60a14947cae963e7fe0cdddbcadcfd2747c10848be94d1c +size 146023 diff --git a/interpro_homologous_superfamily/basic/plot_4.png b/interpro_homologous_superfamily/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..b8288dc225e638bbb6df7e88032b8547f64496a0 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c3066cd66d2a6497f93b4ba1fd0f8846f1adf89c5b7d04b90b3993324b8a165e +size 151317 diff --git a/interpro_homologous_superfamily/basic/plot_5.png b/interpro_homologous_superfamily/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..75dfdd058b1c44c4c1549b0de3a9c732990ceddd --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:71f2708ae7d202e1d5b95ad3ca97bde12b0617cc3ee2fbcf7f14dafaa5ad65d1 +size 148940 diff --git a/interpro_homologous_superfamily/basic/plot_6.png b/interpro_homologous_superfamily/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..6f879bcf3ac56b8ce919c561593ce76d1bffa56f --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:360bf4b41360a692f0886ed0e2225e0bd16c460b3c743c545a251145dfc5368f +size 145266 diff --git a/interpro_homologous_superfamily/basic/plot_7.png b/interpro_homologous_superfamily/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..1d3907fb36a25f02e61fe149cf14e334f480a508 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7da97926d9139da1ca5305708c3a959b78f3aa41276433e132de5ef0cf619deb +size 155066 diff --git a/interpro_homologous_superfamily/basic/plot_8.png b/interpro_homologous_superfamily/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..a0a4933bfb7825d8d42304b906e08f79bfe8c3f7 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:067e21187c6f4cd62166d13d4f4490181ff28f7b4b79109abe30c446297fa69f +size 144923 diff --git a/interpro_homologous_superfamily/basic/plot_9.png b/interpro_homologous_superfamily/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..23a85967f6ec28c916144f633aaea1eeb66075b4 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:826c95b771462dab406b62f00a1c01973ab8b05b27c8e835c8415a0f51aba592 +size 154703 diff --git a/interpro_homologous_superfamily/consensus.joblib b/interpro_homologous_superfamily/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..9ae09d19a47e51ea51954558b221f9ed0cfe0d9e --- /dev/null +++ b/interpro_homologous_superfamily/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9372b10d6a0a0bb88d197887f4b1214daa68b6d4cad1567750a56fca0fc8e65c +size 235449 diff --git a/interpro_homologous_superfamily/df_merge.tsv b/interpro_homologous_superfamily/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..b64311dcd721812d6f8a54d13571ea395f4f0ff8 --- /dev/null +++ b/interpro_homologous_superfamily/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Glutathione S-transferase, C-terminal domain superfamily [IPR036282] 1 17 2.9262715859160653 0.0034305131517333 4.434466019417476 16.66747572815534 0.2357810231502951 0.5538564173973619 3.0446637157573253 1.3736813401106382 0.9202997959616273 0.3110539503026115 0.0022557865829138 0.1029565435856987 0.1920528829609514 0.1010759627458981 0.3004461466081247 +Immunoglobulin E-set [IPR014756] 2 12 2.420881749894205 0.0154829128839588 3.4563106796116503 15.148058252427184 0.2670321239563391 0.4966749963270377 2.426698980572813 2.6319399461427304 0.9943374164221532 0.3081935983105719 1.0 0.2327728239456267 0.0147892391106104 0.1447231035951255 0.2770679255581898 diff --git a/interpro_homologous_superfamily/metrics.json b/interpro_homologous_superfamily/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..5c78d907057c19294b27be08ab193a2b8f435305 --- /dev/null +++ b/interpro_homologous_superfamily/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2772, + "annotations_size": 900, + "title": "Average number of proteins per term", + "value": 4.58 +} \ No newline at end of file diff --git a/interpro_homologous_superfamily/paths.json b/interpro_homologous_superfamily/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..c4fe698e83b12c0dff4c3380346c4570989f3561 --- /dev/null +++ b/interpro_homologous_superfamily/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_homologous_superfamily/fragment/C321/C321_val_log2fc"} \ No newline at end of file diff --git a/interpro_homologous_superfamily/result.tsv b/interpro_homologous_superfamily/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..cbed951071e579c25aeab0c3e0331788c5946470 --- /dev/null +++ b/interpro_homologous_superfamily/result.tsv @@ -0,0 +1,122 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Glutathione S-transferase, C-terminal domain superfamily [IPR036282] 0.7992503333649913 2.9262715859160653 0.0034305131517333 0.9546239011014996 0.0165992571858066 17 Q13505 1 +Cytochrome P450 superfamily [IPR036396] 0.9916967509025272 2.6706600345048495 0.0075702275490601 0.9989289592547176 0.0300141180359211 2 Q6UW02 1 +Calycin [IPR012674] 0.9711191335740068 2.5829405517627073 0.0097962201343093 0.999858054433506 0.0362822967937383 2 P09455 1 +Haem oxygenase-like, multi-helical [IPR016084] 0.9610108303249096 2.5395644357449414 0.0110990598030693 0.9999565978926136 0.0394828214338435 2 P30519 1 +Immunoglobulin E-set [IPR014756] 0.7884402171290603 2.420881749894205 0.0154829128839588 0.9999992039647958 0.0487224531313391 12 A6NIH7,Q13432 2 +Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [IPR029068] 0.9180505415162444 2.353129013801502 0.0186161738159791 0.9999999548137152 0.0551136724815171 2 Q9HC38 1 +GTP-binding protein, orthogonal bundle domain superfamily [IPR023179] 0.8610108303249088 2.1005102433682703 0.0356839804898829 0.9999999999999938 0.0865649122396082 2 Q9NVN8 1 +SGNH hydrolase superfamily [IPR036514] 0.8581227436823092 2.0875718456703427 0.0368364738857214 0.999999999999998 0.0884075373257314 2 Q15102 1 +LAP1C-like, C-terminal domain superfamily [IPR038599] 0.8317689530685904 1.9688917594580488 0.0489655220488187 1.0 0.111285277383679 2 Q5JTV8 1 +Gamma-tubulin complex component, C-terminal domain superfamily [IPR042241] 0.8212996389891682 1.9214486289068131 0.0546751728631615 1.0 0.1202429325974949 2 Q96CW5 1 +Tim10-like domain superfamily [IPR035427] 0.8061371841155216 1.8524588006595024 0.063959968418191 1.0 0.1335590987850857 2 Q9Y5L4 1 +ISWI, HAND domain superfamily [IPR036306] 0.8025270758122725 1.835986239916477 0.0663596917529809 1.0 0.1369810150864285 2 P28370 1 +ABC transporter type 1, transmembrane domain superfamily [IPR036640] 0.7933670416501055 1.7434496024844044 0.0812551103036209 1.0 0.1594121440880928 6 P33527,O75027 2 +Diaphanous, GTPase-binding domain superfamily [IPR044933] 0.7743682310469291 1.706944016053614 0.0878324585447996 1.0 0.1696335036272953 2 Q9NSV4 1 +GMP phosphodiesterase, delta subunit superfamily [IPR037036] 0.9208085070526096 1.5903084808660164 0.1117652879074793 1.0 0.2071123231995291 3 A6NIH7 1 +Translation initiation factor IF-2, domain 3 superfamily [IPR036925] 0.7382671480144377 1.5403294840734298 0.1234800603826415 1.0 0.2213785943115088 2 P46199 1 +SKP1/BTB/POZ domain superfamily [IPR011333] 0.7429285022832313 1.5388178631432885 0.1238487676616155 1.0 0.2215981926350974 6 Q15369,Q9NXV2,Q9P2R3,Q96CX2 4 +Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II [IPR009014] 0.7342960288808636 1.5219434771511942 0.1280232439996198 1.0 0.2268128338575942 2 P29401 1 +PH-like domain superfamily [IPR011993] 0.4191504682052806 1.4213644762354545 0.1552108281704998 1.0 0.2630692002889827 45 P20936,P54105,Q12756,P31749,Q9NQW6,P31751,Q9NVZ3,Q9Y5P4,P26038,Q8NC96,Q9Y3P9 11 +Mitochondrial carrier domain superfamily [IPR023395] 0.4913557822267376 1.3308263128185367 0.1832461678021872 1.0 0.298140234396415 20 Q9BQT8,Q70HW3,Q9H2D1 3 +Pyruvate kinase-like, insert domain superfamily [IPR011037] 0.6920577617328487 1.326103327280555 0.1848054741881784 1.0 0.2993247014643331 2 Q5VT66 1 +tRNA (guanine-N1-)-methyltransferase, N-terminal [IPR029026] 0.6812274368231012 1.2759172446944895 0.2019847744189151 1.0 0.3223668873300469 2 Q5T280 1 +Alpha/beta knot methyltransferases [IPR029028] 0.6812274368231012 1.2759172446944895 0.2019847744189151 1.0 0.3223668873300469 2 Q5T280 1 +Translin, C-terminal [IPR016069] 0.6797833935018014 1.2692304554921263 0.2043588817791364 1.0 0.3238080873260964 2 Q15631 1 +Translin, N-terminal [IPR016068] 0.6797833935018014 1.2692304554921263 0.2043588817791364 1.0 0.3238080873260964 2 Q15631 1 +Translin superfamily [IPR036081] 0.6797833935018014 1.2692304554921263 0.2043588817791364 1.0 0.3238080873260964 2 Q15631 1 +50S ribosomal protein L10, insertion domain superfamily [IPR043164] 0.6768953068592023 1.2558610334883706 0.2091663584805632 1.0 0.3296842778152484 2 P05388 1 +Adenylate cyclase-associated CAP, C-terminal superfamily [IPR036223] 0.6703971119133536 1.2258031960990563 0.220272744179246 1.0 0.3406090788887662 2 Q01518 1 +Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal [IPR016098] 0.6703971119133536 1.2258031960990563 0.220272744179246 1.0 0.3406090788887662 2 Q01518 1 +S-adenosyl-L-methionine-dependent methyltransferase [IPR029063] 0.440321733237718 1.2202507933100812 0.2223698171276751 1.0 0.3425759183563233 30 Q7L592,Q96P11,Q7L2J0,P22061,Q7Z4G4 5 +Nucleic acid-binding, OB-fold [IPR012340] 0.3971009516795756 1.2119085264883804 0.2255473979096129 1.0 0.3458137276297303 43 P18858,P35244,Q8N5C6,Q9Y2R5 4 +RGS domain superfamily [IPR036305] 0.6660649819494547 1.2057857357444324 0.2279001168875614 1.0 0.3488267095217776 2 Q92888 1 +Metallo-dependent phosphatase-like [IPR029052] 0.5978048667741277 1.191227994587879 0.233564092430768 1.0 0.3535529977710299 9 Q6ZT21 1 +Serpin superfamily, domain 1 [IPR042178] 0.6628158844765306 1.1907854679883183 0.2337378151930698 1.0 0.3535529977710299 2 P50454 1 +Serpin superfamily, domain 2 [IPR042185] 0.6628158844765306 1.1907854679883183 0.2337378151930698 1.0 0.3535529977710299 2 P50454 1 +Serpin superfamily [IPR036186] 0.6628158844765306 1.1907854679883183 0.2337378151930698 1.0 0.3535529977710299 2 P50454 1 +PPM-type phosphatase domain superfamily [IPR036457] 0.7616222904676202 1.066767624578038 0.286076781567953 1.0 0.4193307873145891 4 Q9H0C8,P49593 2 +Macro domain-like [IPR043472] 0.7611047232774336 1.0648844763277934 0.2869282107591955 1.0 0.4198949425744324 4 Q9P0M6,P28838 2 +Chaperone J-domain superfamily [IPR036869] 0.4628330555051368 0.9919204461104948 0.3212363343608082 1.0 0.4618413752791172 15 Q13217,Q96EY1 2 +Protein kinase-like domain superfamily [IPR011009] 0.3641717577766417 0.951749277280414 0.3412241517327146 1.0 0.4866905492225723 51 Q9UHY1,O95747,Q14004,O43318,Q7KZI7,P31749,P31751,P35790,Q99640,P36507,Q13043 11 +Moesin tail domain superfamily [IPR008954] 0.7415268134999096 0.9335502387907456 0.3505359440593913 1.0 0.4983923375252009 3 P26038 1 +Immunoglobulin-like fold [IPR013783] 0.4113099396115416 0.9249797955450224 0.354976417251301 1.0 0.5039097405775567 26 Q96KP1,P78310,Q9Y639,Q8IZT6 4 +Ribokinase-like [IPR029056] 0.7372159682543662 0.918132641382713 0.3585494278172292 1.0 0.508180291394498 3 O00764 1 +Neurolysin/Thimet oligopeptidase, N-terminal [IPR024080] 0.5971119133573961 0.8918174413515892 0.3724907915787729 1.0 0.5201536733484914 2 P52888 1 +Rho GTPase activation protein [IPR008936] 0.5269634520139453 0.8036451013762486 0.4216019679377041 1.0 0.5766592266625131 8 P20936,Q01968 2 +Dbl homology (DH) domain superfamily [IPR035899] 0.7035030697002491 0.7991436484489934 0.4242071227194337 1.0 0.5793420492374663 3 Q92974,Q14155 2 +Coatomer/calthrin adaptor appendage, C-terminal subdomain [IPR009028] 0.5517794767169438 0.7599751098487135 0.447269462974708 1.0 0.6062387299355982 6 Q10567 1 +TBP domain superfamily [IPR012295] 0.5517794767169438 0.7599751098487135 0.447269462974708 1.0 0.6062387299355982 6 Q10567 1 +Ankyrin repeat-containing domain superfamily [IPR036770] 0.3959640748700881 0.7064556925332505 0.4799047973154069 1.0 0.6398730630872093 19 O75832,P42771,Q8IUH4,Q8IWZ3,Q9BQG2,Q9P2R3,P58546,Q9H6S0,Q86XL3,Q96KQ7 10 +Clathrin adaptor, appendage, Ig-like subdomain superfamily [IPR013041] 0.5105671892858743 0.6650260517831326 0.506033830358199 1.0 0.6682188484559581 7 Q10567 1 +K Homology domain, type 1 superfamily [IPR036612] 0.3706090138351844 0.6539116880367892 0.5131687033250856 1.0 0.6727668933493633 26 Q96PU8,Q8IWZ3,Q15366,Q9Y6M1,Q9Y2W6,P51116 6 +AH/BAR domain superfamily [IPR027267] 0.4187575754108641 0.6508031959986077 0.5151735368621875 1.0 0.6729407593265149 13 Q9UQB8 1 +Neurolysin/Thimet oligopeptidase, domain 2 [IPR024077] 0.6570982767949234 0.6415865782722872 0.5211416498745343 1.0 0.6797499780972186 3 Q99797 1 +Prefoldin [IPR009053] 0.6320119295848023 0.6137983194359358 0.5393486079326177 1.0 0.6964329227250444 4 Q99471,O15212 2 +TGS-like [IPR012676] 0.5125928667610686 0.610038960878204 0.541835999043075 1.0 0.6976429172228434 6 P55039,Q9BW92 2 +Caspase-like domain superfamily [IPR029030] 0.6417600462103835 0.5916315512063265 0.5540973412940866 1.0 0.7113945893932638 3 P42574 1 +FAD/NAD(P)-binding domain superfamily [IPR036188] 0.3775359925482548 0.57844263764594 0.5629653145346776 1.0 0.7196999759676276 18 Q9UHG3,P22570,Q6NUM9 3 +RNA polymerase Rpb1, domain 3 superfamily [IPR042102] 0.6348565752054931 0.569561893595119 0.5689748802551906 1.0 0.723181183776039 3 O95602 1 +RNA polymerase Rpb1, funnel domain superfamily [IPR038120] 0.6348565752054931 0.569561893595119 0.5689748802551906 1.0 0.723181183776039 3 O95602 1 +RNA polymerase Rpb1, clamp domain superfamily [IPR044893] 0.6348565752054931 0.569561893595119 0.5689748802551906 1.0 0.723181183776039 3 O95602 1 +Ribonuclease H-like superfamily [IPR012337] 0.3752184840994939 0.5191473726983197 0.6036579752422702 1.0 0.7566743422256869 15 Q8N5C6,Q07864 2 +Ubiquitin-activating enzyme E1, FCCH domain superfamily [IPR042302] 0.4989169675090191 0.4838545128901917 0.6284891242953294 1.0 0.7823516070066342 2 P22314 1 +Ubiquitin-activating enzyme E1, C-terminal domain superfamily [IPR038252] 0.4989169675090191 0.4838545128901917 0.6284891242953294 1.0 0.7823516070066342 2 P22314 1 +Ubiquitin-activating enzyme E1, SCCH domain [IPR042063] 0.4989169675090191 0.4838545128901917 0.6284891242953294 1.0 0.7823516070066342 2 P22314 1 +Beta-grasp domain superfamily [IPR012675] 0.4607937123870488 0.4770613506040003 0.6333184353391688 1.0 0.7861884024900025 7 P55039,Q9BW92 2 +SH3-like domain superfamily [IPR036028] 0.3440402081140657 0.472315793434932 0.6367013989990649 1.0 0.7882315021402918 24 Q9UQB8,Q92783 2 +HSP90, C-terminal domain [IPR037196] 0.5868803853317258 0.4722954870277888 0.6367158911733246 1.0 0.7882315021402918 4 Q12931,P08238 2 +Band 7/SPFH domain superfamily [IPR036013] 0.4550052142052142 0.4079660712333643 0.6832985843408004 1.0 0.8279843195943279 6 Q99623,Q9UJZ1 2 +Acyl-CoA dehydrogenase-like, C-terminal [IPR036250] 0.4151169843275943 0.4063750657572537 0.6844670375313111 1.0 0.8279843195943279 9 O15254 1 +Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily [IPR009100] 0.4151169843275943 0.4063750657572537 0.6844670375313111 1.0 0.8279843195943279 9 O15254 1 +CDC48 domain 2-like superfamily [IPR029067] 0.4682310469314025 0.3750171436692793 0.7076477167740385 1.0 0.8424377580643315 2 P55072 1 +Aspartate decarboxylase-like domain superfamily [IPR009010] 0.4682310469314025 0.3750171436692793 0.7076477167740385 1.0 0.8424377580643315 2 P55072 1 +Homeobox-like domain superfamily [IPR009057] 0.340983764409952 0.3577375007473142 0.7205397662815678 1.0 0.850207146374774 15 Q96G23,O60264,O60341,Q7Z3K3,Q8TAQ2,Q8NB78,Q8IXM2,P28370 8 +SNF2-like, N-terminal domain superfamily [IPR038718] 0.3651032325444613 0.3493232443786945 0.7268466497937562 1.0 0.8534461664308985 12 Q14527,Q86WJ1,Q2NKX8,P46100,P28370 5 +Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1 [IPR042449] 0.5508230504603381 0.3275548315089669 0.7432482785056895 1.0 0.8682850977898535 3 Q9UBT2 1 +Calreticulin/calnexin, P domain superfamily [IPR009033] 0.5505182581020889 0.3267844777327577 0.7438309004399746 1.0 0.8682850977898535 3 O14967 1 +RuvBL1/2, DNA/RNA binding domain [IPR042487] 0.4296028880866373 0.2569972183136745 0.7971809204379441 1.0 0.9104858228352154 2 Q9Y265 1 +Nucleoside phosphorylase superfamily [IPR035994] 0.4281588447653369 0.2530490461269676 0.8002303128919976 1.0 0.9128102428425828 2 P00491 1 +2Fe-2S ferredoxin-like superfamily [IPR036010] 0.4238267148014367 0.2414171643883381 0.8092318108575236 1.0 0.919581603247186 2 P28331 1 +Ribosomal protein L30, ferredoxin-like fold domain superfamily [IPR036919] 0.4162454873646136 0.221839297069003 0.8244389869061615 1.0 0.9251809079994332 2 P18124 1 +SAP domain superfamily [IPR036361] 0.3276309501231216 0.215993211646484 0.8289930390016365 1.0 0.927085360823078 12 Q9NWH9 1 +Immunoglobulin-like domain superfamily [IPR036179] 0.3331158404412411 0.202842290869171 0.8392583016535995 1.0 0.9336618930633368 11 Q9Y639 1 +Histone-fold [IPR009072] 0.3779179275738465 0.1922439135031938 0.8475511493657217 1.0 0.93961548304673 6 Q9P0M6,P62805 2 +PX domain superfamily [IPR036871] 0.3417984009240637 0.1597214038641189 0.8731005395127913 1.0 0.9617998599284114 8 Q13596 1 +GHMP kinase, C-terminal domain superfamily [IPR036554] 0.4694835680751152 0.1567333830756483 0.8754549763294543 1.0 0.9620384355268728 3 Q03426,P53602 2 +Galactose mutarotase-like domain superfamily [IPR011013] 0.4668337414270179 0.1524209307976524 0.8788549495612386 1.0 0.96249992081764 3 P10253 1 +Tubulin/FtsZ-like, C-terminal domain [IPR037103] 0.3559066808906926 0.145837185258275 0.884049920122407 1.0 0.96249992081764 6 P68371,P04350,Q13885 3 +Tubulin/FtsZ, C-terminal [IPR008280] 0.3559066808906926 0.145837185258275 0.884049920122407 1.0 0.96249992081764 6 P68371,P04350,Q13885 3 +Tubulin, C-terminal [IPR023123] 0.3559066808906926 0.145837185258275 0.884049920122407 1.0 0.96249992081764 6 P68371,P04350,Q13885 3 +Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm [IPR010978] 0.3815884476534232 0.1453551383833572 0.8844304827957647 1.0 0.96249992081764 2 P49591 1 +Serine-tRNA synthetase, type1, N-terminal domain superfamily [IPR042103] 0.3815884476534232 0.1453551383833572 0.8844304827957647 1.0 0.96249992081764 2 P49591 1 +Formin, FH2 domain superfamily [IPR042201] 0.4420504115439202 0.1362107167654714 0.8916547033759532 1.0 0.9668551310747144 4 Q9NSV4 1 +Bromo adjacent homology (BAH) domain superfamily [IPR043151] 0.4360549132948095 0.1272375946881081 0.8987523509197701 1.0 0.9713903262700552 4 O94776,Q13330,P26358 3 +ATPase, F1/V1 complex, beta/alpha subunit, C-terminal [IPR024034] 0.3689530685920509 0.1228537192064487 0.9022229346344088 1.0 0.9713903262700552 2 P06576 1 +Winged helix DNA-binding domain superfamily [IPR036390] 0.2549901837104925 0.1225408060524133 0.9024707309307948 1.0 0.9713903262700552 38 P10412,P16403,P39019,Q7L2H7,P07305,Q96HY6 6 +Pyridoxal phosphate-dependent transferase, small domain [IPR015422] 0.2750639747971303 0.118029275427881 0.906044461567958 1.0 0.9713903262700552 14 O95470 1 +Sterile alpha motif/pointed domain superfamily [IPR013761] 0.4289210316079428 0.1171085409601204 0.9067740416032668 1.0 0.9713903262700552 4 Q9Y3Z3,Q9UQR0 2 +Anticodon-binding domain superfamily [IPR036621] 0.3451391398626668 0.1161546190591894 0.9075300019704716 1.0 0.9713903262700552 5 Q9BW92,Q9HCD5,P41250,P07814 4 +6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily [IPR008927] 0.3183879838455546 0.1122134786955109 0.9106541422160837 1.0 0.9714045876036708 8 Q16836,P32322 2 +Rossmann-like alpha/beta/alpha sandwich fold [IPR014729] 0.2662613439452924 0.1078112183696482 0.914145443790551 1.0 0.972359550530944 22 P49589,Q13057,Q5JPH6 3 +Armadillo-like helical [IPR011989] 0.2463934171775098 0.102346916774338 0.9184813165965976 1.0 0.972359550530944 96 Q9C0E2,Q9BTY7,P52294,Q14997,Q9Y376,O15397,Q9NTI5,Q9BU89,Q96JJ3,Q8IZT6,Q14671,Q10567,Q92797,O94973,P42695,Q7Z5K2,P14923,Q9NSV4,Q9UI26,O43592 20 +PapD-like superfamily [IPR008962] 0.431202600216686 0.1023193048001355 0.9185032327100662 1.0 0.972359550530944 3 Q8NHP6,O95292 2 +Phenylalanyl-tRNA synthetase-like, B3/B4 [IPR020825] 0.3530685920577556 0.0985651700117353 0.9214835256191208 1.0 0.9733980904427332 2 Q8N1G4 1 +Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal [IPR015955] 0.4039017341040576 0.08620682132637 0.9313020082627534 1.0 0.9786973758837336 4 P07195,P40925,P40926 3 +Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily [IPR036940] 0.3936439147706707 0.0646998450709367 0.9484129861812453 1.0 0.9844399657715796 3 P42345,O00443 2 +Winged helix-like DNA-binding domain superfamily [IPR036388] 0.2422141381156379 0.0637968361574145 0.9491319975095684 1.0 0.9844399657715796 38 Q7Z2W4,P05455,P10412,Q5SSJ5,P16403,P16402,P39019,O60341,Q12948,Q8N3C0,Q15149,Q92522,P07305,Q8TAQ2,Q8NB78,P62851,Q96HY6,Q13617 18 +ENTH/VHS [IPR008942] 0.2859062379314764 0.0624148891672648 0.9502324382365044 1.0 0.9844399657715796 8 Q92783 1 +NTF2-like domain superfamily [IPR032710] 0.3005002775603249 0.0620455474750301 0.95052656020862 1.0 0.9844399657715796 6 Q9BRJ2,Q13283 2 +GINS, helical bundle-like domain superfamily [IPR036224] 0.3787390823100499 0.0620393719861559 0.9505314780616696 1.0 0.9844399657715796 4 Q9BRX5,Q9Y248 2 +ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily [IPR036121] 0.3690863127482811 0.0475911937626981 0.9620420504378906 1.0 0.9906611503365006 3 P25705,P06576 2 +Six-hairpin glycosidase-like superfamily [IPR012341] 0.3468208092485564 0.0402545222830567 0.9678902103279844 1.0 0.9951503039542668 4 Q9NS86,Q13724,O43813 3 +Pyridoxal phosphate-dependent transferase, major domain [IPR015421] 0.2353665812622581 0.0333403457674679 0.9734031803610724 1.0 0.9961663322970604 15 O95470 1 +Pyridoxal phosphate-dependent transferase [IPR015424] 0.2353665812622581 0.0333403457674679 0.9734031803610724 1.0 0.9961663322970604 15 O95470 1 +EF-hand domain pair [IPR011992] 0.2382146793711048 0.0325551917317318 0.9740293026904592 1.0 0.9961663322970604 43 O95202,Q9H4M9,P80303,O95302,P35609 5 +Cullin homology domain superfamily [IPR036317] 0.2580411998554394 0.028944899682249 0.9769085358404488 1.0 0.9969951081530828 5 Q13616,Q93034,Q13617,Q13618 4 +Longin-like domain superfamily [IPR011012] 0.2462289116896742 0.0265288514585299 0.9788355215571511 1.0 0.9976805995486252 10 P08240,O15498 2 +Histidine kinase/HSP90-like ATPase superfamily [IPR036890] 0.2467438494934822 0.0251268901470277 0.9799537517148088 1.0 0.9976904712028598 8 Q12931,Q02880,P11388,P14625,Q15120,P07900,P08238 7 +Kinesin motor domain superfamily [IPR036961] 0.2280674368203929 0.0210709586493045 0.983189051390614 1.0 0.99791329690222 16 O00139,Q02241,Q99661,Q12756 4 +Zinc finger C2H2 superfamily [IPR036236] 0.2258153140044747 0.0192924757723467 0.9846077862768572 1.0 0.99791329690222 15 Q96KM6,Q969S3 2 +6-phosphogluconate dehydrogenase, domain 2 [IPR013328] 0.2586705202312169 0.0157458812523594 0.9874371235794572 1.0 0.9985319227207994 4 Q16836,P31937,P52209 3 +Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily [IPR018163] 0.2227042660882071 0.0125430507509355 0.989992355875126 1.0 0.9988712110847684 6 Q9BW92,Q9NYK5,Q5JTZ9,P26639,P49588 5 diff --git a/interpro_homologous_superfamily/selections.json b/interpro_homologous_superfamily/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..9d06339e50559df2611d9597beb98bd68ddece9e --- /dev/null +++ b/interpro_homologous_superfamily/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 domain superfamily [IPR036815]", "2Fe-2S ferredoxin-like superfamily [IPR036010]", "30s ribosomal protein S13, C-terminal [IPR027437]", "4'-phosphopantetheinyl transferase domain superfamily [IPR037143]", "5'-3' exonuclease, C-terminal domain superfamily [IPR036279]", "50S ribosomal protein L10, insertion domain superfamily [IPR043164]", "50S ribosomal protein L30e-like [IPR029064]", "6-phosphogluconate dehydrogenase, domain 2 [IPR013328]", "6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily [IPR008927]", "AAR2, C-terminal domain superfamily [IPR038514]", "AAR2, N-terminal domain superfamily [IPR038516]", "ABC transporter type 1, transmembrane domain superfamily [IPR036640]", "ACP-like superfamily [IPR036736]", "ADF-H/Gelsolin-like domain superfamily [IPR029006]", "ADP-ribosylation/Crystallin J1 superfamily [IPR036705]", "AF1104-like superfamily [IPR036075]", "AH/BAR domain superfamily [IPR027267]", "AICAR transformylase, duplicated domain superfamily [IPR024051]", "AICAR transformylase, insert domain superfamily [IPR024050]", "AMP-binding enzyme, C-terminal domain superfamily [IPR045851]", "ANL, N-terminal domain [IPR042099]", "ANTH domain superfamily [IPR014712]", "AP-2 complex subunit mu, C-terminal superfamily [IPR036168]", "ARFGAP/RecO-like zinc finger [IPR037278]", "ARID DNA-binding domain superfamily [IPR036431]", "ATP synthase subunit alpha, N-terminal domain-like superfamily [IPR023366]", "ATP synthase, F0 complex, subunit A superfamily [IPR035908]", "ATP synthase, F0 complex, subunit D superfamily, mitochondrial [IPR036228]", "ATP synthase, F1 complex, gamma subunit superfamily [IPR035968]", "ATP synthase, alpha subunit, C-terminal domain superfamily [IPR038376]", "ATP-NAD kinase, PpnK-type, C-terminal [IPR017437]", "ATP-grasp fold, subdomain 1 [IPR013815]", "ATP:guanido phosphotransferase, N-terminal domain superfamily [IPR036802]", "ATPase, F1/V1 complex, beta/alpha subunit, C-terminal [IPR024034]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily [IPR036121]", "ATPase, V1 complex, subunit H, C-terminal domain superfamily [IPR038497]", "ATPase, nucleotide binding domain [IPR043129]", "Acetylglutamate kinase-like superfamily [IPR036393]", "Aconitase, domain 2 [IPR015932]", "Aconitase, iron-sulfur domain [IPR036008]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 [IPR015931]", "Aconitase/3-isopropylmalate dehydratase, swivel [IPR015928]", "Actin-crosslinking [IPR008999]", "Actin-related protein 2/3 complex subunit 3 superfamily [IPR036753]", "Actin-related protein 2/3 complex subunit 5 superfamily [IPR036743]", "Activator of Hsp90 ATPase, Aha1 [IPR036338]", "Acyl transferase domain superfamily [IPR001227]", "Acyl transferase/acyl hydrolase/lysophospholipase [IPR016035]", "Acyl-CoA N-acyltransferase [IPR016181]", "Acyl-CoA binding protein superfamily [IPR035984]", "Acyl-CoA dehydrogenase-like, C-terminal [IPR036250]", "Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily [IPR009100]", "Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily [IPR037069]", "Adenosylhomocysteinase-like superfamily [IPR042172]", "Adenylate cyclase-associated CAP, C-terminal superfamily [IPR036223]", "Adenylate cyclase-associated CAP, N-terminal domain superfamily [IPR036222]", "Adenylate kinase, active site lid domain superfamily [IPR036193]", "Adenylosuccinate synthetase, domain 1 [IPR042109]", "Adenylosuccinate synthetase, domain 2 [IPR042110]", "Adenylosuccinate synthetase, domain 3 [IPR042111]", "Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily [IPR018162]", "Alba-like domain superfamily [IPR036882]", "Aldehyde dehydrogenase, C-terminal [IPR016163]", "Aldehyde dehydrogenase, N-terminal [IPR016162]", "Aldehyde/histidinol dehydrogenase [IPR016161]", "Aldolase-type TIM barrel [IPR013785]", "Alkaline-phosphatase-like, core domain superfamily [IPR017850]", "Allosteric substrate binding domain superfamily [IPR029009]", "Alpha-D-phosphohexomutase, C-terminal domain superfamily [IPR036900]", "Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III [IPR016055]", "Alpha-catenin/vinculin-like superfamily [IPR036723]", "Alpha-glycerophosphate oxidase, C-terminal domain superfamily [IPR038299]", "Alpha-helical ferredoxin [IPR009051]", "Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain superfamily [IPR036784]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily [IPR037151]", "Alpha/Beta hydrolase fold [IPR029058]", "Alpha/beta knot methyltransferases [IPR029028]", "Amidase signature (AS) superfamily [IPR036928]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 [IPR020751]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding superfamily [IPR008925]", "Aminoacyl-tRNA synthetase, class Ia, anticodon-binding [IPR009080]", "Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097]", "Aminotransferase-like, PLP-dependent enzymes [IPR036038]", "Ankyrin repeat-containing domain superfamily [IPR036770]", "Annexin superfamily [IPR037104]", "Anticodon-binding domain superfamily [IPR036621]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain superfamily [IPR036732]", "ApaG domain superfamily [IPR036767]", "ArfGAP domain superfamily [IPR038508]", "Arginyl tRNA synthetase N-terminal domain superfamily [IPR036695]", "Armadillo-like helical [IPR011989]", "Armadillo-type fold [IPR016024]", "Arp2/3 complex subunit 2/4 [IPR034666]", "Arrestin-like, C-terminal [IPR014752]", "Aspartate decarboxylase-like domain superfamily [IPR009010]", "Aspartate/ornithine carbamoyltransferase superfamily [IPR036901]", "Aspartic peptidase domain superfamily [IPR021109]", "At2g17340, three-helix bundle domain [IPR035073]", "B30.2/SPRY domain superfamily [IPR043136]", "BAG domain superfamily [IPR036533]", "BEACH domain superfamily [IPR036372]", "BRCT domain superfamily [IPR036420]", "BRK domain superfamily [IPR037259]", "BRO1 domain superfamily [IPR038499]", "BSD domain superfamily [IPR035925]", "Bacterial exopeptidase dimerisation domain [IPR036264]", "Band 7/SPFH domain superfamily [IPR036013]", "Barrier-to-autointegration factor, BAF superfamily [IPR036617]", "Bcl-2-like superfamily [IPR036834]", "Beta-Galactosidase/glucuronidase domain superfamily [IPR036156]", "Beta-grasp domain superfamily [IPR012675]", "Beta-hexosaminidase-like, domain 2 [IPR029018]", "Beta-lactamase/transpeptidase-like [IPR012338]", "Branched-chain-amino-acid aminotransferase-like, C-terminal [IPR043132]", "Branched-chain-amino-acid aminotransferase-like, N-terminal [IPR043131]", "Bromo adjacent homology (BAH) domain superfamily [IPR043151]", "Bromodomain-like superfamily [IPR036427]", "C2 domain superfamily [IPR035892]", "CAP Gly-rich domain superfamily [IPR036859]", "CCR4-NOT subunit 1, TTP binding domain superfamily [IPR038535]", "CDC48 domain 2-like superfamily [IPR029067]", "CH domain superfamily [IPR036872]", "CRAL-TRIO lipid binding domain superfamily [IPR036865]", "CRAL/TRIO, N-terminal domain superfamily [IPR036273]", "CRIB domain superfamily [IPR036936]", "CSTF1, dimerization domain superfamily [IPR038184]", "Cadherin-like superfamily [IPR015919]", "Calcyclin-binding protein, N-terminal [IPR037201]", "Calpain large subunit, domain III superfamily [IPR036213]", "Calreticulin/calnexin, P domain superfamily [IPR009033]", "Calycin [IPR012674]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily [IPR036480]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily [IPR036897]", "Carbohydrate-binding-like fold [IPR013784]", "Carboxypeptidase-like, regulatory domain superfamily [IPR008969]", "Carnitine o-acyltransferase, N-terminal [IPR042572]", "Casein kinase II subunit beta-like [IPR035991]", "Casein kinase II, regulatory subunit, N-terminal [IPR016149]", "Caspase-like domain superfamily [IPR029030]", "Catenin binding domain superfamily [IPR027397]", "Cathepsin C, exclusion domain superfamily [IPR036496]", "Cation efflux transmembrane domain superfamily [IPR027469]", "Cdc37, Hsp90-binding domain superfamily [IPR038189]", "Cell division control protein 73, C-terminal domain superfamily [IPR038103]", "Chaperone J-domain superfamily [IPR036869]", "Chitinase insertion domain superfamily [IPR029070]", "Chloramphenicol acetyltransferase-like domain superfamily [IPR023213]", "Chloride channel, core [IPR014743]", "Choline/Carnitine o-acyltransferase, domain 2 [IPR042231]", "Chromo-like domain superfamily [IPR016197]", "Citrate synthase superfamily [IPR036969]", "Citrate synthase-like, large alpha subdomain [IPR016142]", "Citrate synthase-like, small alpha subdomain [IPR016143]", "Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm [IPR010978]", "Class I glutamine amidotransferase-like [IPR029062]", "Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) [IPR045864]", "Class II aldolase/adducin N-terminal domain superfamily [IPR036409]", "Clathrin adaptor, appendage, Ig-like subdomain superfamily [IPR013041]", "Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain [IPR013037]", "Clathrin heavy chain, N-terminal [IPR016025]", "Clp1, C-terminal domain superfamily [IPR038238]", "Clp1, N-terminal beta-sandwich domain superfamily [IPR038239]", "ClpP/crotonase-like domain superfamily [IPR029045]", "Coatomer, gamma subunit, appendage domain superfamily [IPR037067]", "Coatomer/calthrin adaptor appendage, C-terminal subdomain [IPR009028]", "Cobalamin (vitamin B12)-dependent enzyme, catalytic [IPR016176]", "Cobalamin adenosyltransferase-like superfamily [IPR036451]", "Cobalamin-binding domain superfamily [IPR036724]", "Concanavalin A-like lectin/glucanase domain superfamily [IPR013320]", "Core-binding factor, beta subunit superfamily [IPR036552]", "Creatinase/Aminopeptidase P/Spt16, N-terminal [IPR029149]", "Creatinase/aminopeptidase-like [IPR036005]", "Cullin homology domain superfamily [IPR036317]", "Cullin repeat-like-containing domain superfamily [IPR016159]", "Cupredoxin [IPR008972]", "Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal [IPR016098]", "Cyclic nucleotide-binding-like [IPR018490]", "Cyclic phosphodiesterase [IPR009097]", "Cyclin-like superfamily [IPR036915]", "Cyclophilin-like domain superfamily [IPR029000]", "Cytidine deaminase-like [IPR016193]", "Cytochrome C oxidase subunit II, transmembrane domain superfamily [IPR036257]", "Cytochrome P450 superfamily [IPR036396]", "Cytochrome b-c1 complex subunit 7 superfamily [IPR036544]", "Cytochrome b-c1 complex subunit 8 superfamily [IPR036642]", "Cytochrome b-c1 complex subunit 9 superfamily [IPR036656]", "Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400]", "Cytochrome bc1 complex subunit Rieske, transmembrane domain superfamily [IPR037008]", "Cytochrome c oxidase subunit IV superfamily [IPR036639]", "Cytochrome c oxidase subunit VIIc superfamily [IPR036636]", "Cytochrome c oxidase, subunit VIIa superfamily [IPR036539]", "Cytochrome c oxidase, subunit Va/VI superfamily [IPR036545]", "Cytochrome c oxidase, subunit Vb superfamily [IPR036972]", "Cytochrome c-like domain superfamily [IPR036909]", "Cytochrome c1, transmembrane anchor, C-terminal [IPR021157]", "Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily [IPR011048]", "DHBP synthase RibB-like alpha/beta domain superfamily [IPR017945]", "DHS-like NAD/FAD-binding domain superfamily [IPR029035]", "DNA breaking-rejoining enzyme, catalytic core [IPR011010]", "DNA fragmentation factor 45kDa, C-terminal [IPR027296]", "DNA ligase, ATP-dependent, N-terminal domain superfamily [IPR036599]", "DNA mismatch repair protein MutS, N-terminal [IPR016151]", "DNA mismatch repair protein MutS, core domain superfamily [IPR036187]", "DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal [IPR008921]", "DNA polymerase alpha, subunit B, N-terminal domain superfamily [IPR043034]", "DNA polymerase alpha, zinc finger domain superfamily [IPR038256]", "DNA polymerase family B, thumb domain [IPR042087]", "DNA polymerase, palm domain superfamily [IPR023211]", "DNA repair protein XRCC4-like, C-terminal [IPR014751]", "DNA topoisomerase I, DNA binding, N-terminal domain 1 [IPR013034]", "DNA topoisomerase I, DNA binding, N-terminal domain 2 [IPR013030]", "DNA topoisomerase I, DNA binding, eukaryotic-type, N-terminal domain superfamily [IPR036202]", "DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type [IPR014711]", "DNA topoisomerase I, catalytic core, alpha/beta subdomain [IPR014727]", "DNA topoisomerase, type IIA, alpha-helical domain superfamily [IPR013757]", "DNA topoisomerase, type IIA, domain A, alpha-beta [IPR013758]", "DNA topoisomerase, type IIA, subunit B, C-terminal [IPR013759]", "DNA topoisomerase, type IIA-like domain superfamily [IPR013760]", "DNA-binding domain superfamily [IPR016177]", "DNA-directed RNA polymerase, N-terminal domain superfamily [IPR037159]", "DNA-directed RNA polymerase, insert domain superfamily [IPR036643]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily [IPR037033]", "DNA/RNA non-specific endonuclease superfamily [IPR044929]", "DNA/RNA polymerase superfamily [IPR043502]", "DUSP-like superfamily [IPR035927]", "Daxx, N-terminal domain superfamily [IPR038298]", "Dbl homology (DH) domain superfamily [IPR035899]", "Death-like domain superfamily [IPR011029]", "Deoxyhypusine synthase superfamily [IPR036982]", "Diaphanous, GTPase-binding domain superfamily [IPR044933]", "Dicer dimerisation domain superfamily [IPR038248]", "Dihydrofolate reductase-like domain superfamily [IPR024072]", "Dimeric alpha-beta barrel [IPR011008]", "Diphthamide synthesis DPH1/DPH2, domain 1 [IPR042263]", "Diphthamide synthesis DPH1/DPH2, domain 3 [IPR042265]", "Dynein heavy chain AAA lid domain superfamily [IPR042219]", "Dynein heavy chain, AAA1 domain, small subdomain [IPR043157]", "Dynein heavy chain, C-terminal domain, barrel region [IPR043160]", "Dynein heavy chain, domain 2, N-terminal [IPR042222]", "Dynein heavy chain, linker, subdomain 3 [IPR042228]", "Dynein light chain superfamily [IPR037177]", "E3-binding domain superfamily [IPR036625]", "EB1, C-terminal domain superfamily [IPR036133]", "EF-G domain III/V-like [IPR035647]", "EF-hand domain pair [IPR011992]", "ENTH/VHS [IPR008942]", "ERO1-like superfamily [IPR037192]", "ERV/ALR sulfhydryl oxidase domain superfamily [IPR036774]", "ESCRT assembly domain [IPR037202]", "EXOC6/PINT-1/Sec15/Tip20, C-terminal, domain 2 [IPR042044]", "EYA domain superfamily [IPR038102]", "Elongation factor EF1B gamma, C-terminal domain superfamily [IPR036433]", "Elongation factor Ts, dimerisation domain superfamily [IPR036402]", "Endonuclease/exonuclease/phosphatase superfamily [IPR036691]", "Endoplasmic reticulum resident protein 29, C-terminal domain superfamily [IPR036356]", "Enhancer of mRNA-decapping protein 4, conserved C-terminal domain [IPR044938]", "Enhancer of rudimentary superfamily [IPR035912]", "Enolase-like, C-terminal domain superfamily [IPR036849]", "Enolase-like, N-terminal [IPR029017]", "Enoyl-CoA hydratase, C-terminal [IPR014748]", "Eukaryotic translation initiation factor 3-like domain superfamily [IPR023194]", "Exocyst complex component EXOC6/Sec15, C-terminal, domain 1 [IPR042045]", "Exoribonuclease, PH domain 2 superfamily [IPR036345]", "F-actin capping protein, alpha subunit, domain 1 [IPR042489]", "F-actin-capping protein subunit alpha/beta [IPR037282]", "F-actin-capping protein subunit alpha/beta, domain 2 [IPR042276]", "F-actin-capping protein subunit beta, N-terminal domain [IPR043175]", "F-box-like domain superfamily [IPR036047]", "F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily [IPR026015]", "FAD-binding, type PCMH, subdomain 1 [IPR016167]", "FAD-binding, type PCMH, subdomain 2 [IPR016169]", "FAD-binding, type PCMH-like superfamily [IPR036318]", "FAD-linked oxidase-like, C-terminal [IPR016164]", "FAD/NAD(P)-binding domain superfamily [IPR036188]", "FAD/NAD-linked reductase, dimerisation domain superfamily [IPR016156]", "FERM superfamily, second domain [IPR035963]", "FERM/acyl-CoA-binding protein superfamily [IPR014352]", "FF domain superfamily [IPR036517]", "FIP-RBD, C-terminal domain superfamily [IPR037245]", "FKBP12-rapamycin binding domain superfamily [IPR036738]", "FMN-binding split barrel [IPR012349]", "FTO, C-terminal domain superfamily [IPR038413]", "Ferredoxin-NADP reductase (FNR), nucleotide-binding domain [IPR039261]", "Ferritin-like superfamily [IPR009078]", "Fibronectin type II domain superfamily [IPR036943]", "Fibronectin type III superfamily [IPR036116]", "Flavoprotein-like superfamily [IPR029039]", "Folliculin, DENN domain, C-terminal superfamily [IPR044886]", "Formin, FH2 domain superfamily [IPR042201]", "Formyl transferase, N-terminal domain superfamily [IPR036477]", "Formyl transferase-like, C-terminal domain superfamily [IPR011034]", "Fumarase/histidase, N-terminal [IPR024083]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily [IPR037099]", "Fumarylacetoacetase, N-terminal domain superfamily [IPR036462]", "Fumarylacetoacetase-like, C-terminal domain superfamily [IPR036663]", "G protein alpha subunit, helical insertion [IPR011025]", "G-protein gamma-like domain superfamily [IPR036284]", "GAD-like domain superfamily [IPR004115]", "GAR domain superfamily [IPR036534]", "GHMP kinase, C-terminal domain superfamily [IPR036554]", "GINS complex, subunit Psf3 superfamily [IPR038437]", "GINS, helical bundle-like domain superfamily [IPR036224]", "GM2-AP, lipid-recognition domain superfamily [IPR036846]", "GMP phosphodiesterase, delta subunit superfamily [IPR037036]", "GOLD domain superfamily [IPR036598]", "GSKIP domain superfamily [IPR023231]", "GTF2I-like repeat superfamily [IPR036647]", "GTP-binding protein TrmE/Aminomethyltransferase GcvT, domain 1 [IPR027266]", "GTP-binding protein, orthogonal bundle domain superfamily [IPR023179]", "GTP1/OBG domain superfamily [IPR036726]", "GYF-like domain superfamily [IPR035445]", "Galactose mutarotase-like domain superfamily [IPR011013]", "Galactose oxidase/kelch, beta-propeller [IPR011043]", "Galactose-binding-like domain superfamily [IPR008979]", "Gamma-glutamyl cyclotransferase-like superfamily [IPR036568]", "Gamma-tubulin complex component, C-terminal domain superfamily [IPR042241]", "Gelsolin-like domain superfamily [IPR036180]", "Globular protein, non-globular alpha/beta subunit [IPR011070]", "Glutamine synthetase/guanido kinase, catalytic domain [IPR014746]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 1 [IPR042558]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 2 [IPR042559]", "Glutathione S-transferase, C-terminal domain superfamily [IPR036282]", "Glutathione synthase, C-terminal, eukaryotic [IPR014709]", "Glutathione synthase, N-terminal, eukaryotic [IPR014049]", "Glutathione synthase, alpha-helical [IPR014042]", "Glutathione synthase, substrate-binding domain superfamily [IPR037013]", "Glycolipid transfer protein superfamily [IPR036497]", "Glycoside hydrolase superfamily [IPR017853]", "Glycoside hydrolase-type carbohydrate-binding [IPR014718]", "Glycosyl hydrolase family 63, N-terminal domain superfamily [IPR038518]", "Glycosyl hydrolase, all-beta [IPR013780]", "Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [IPR029068]", "GroEL-like apical domain superfamily [IPR027409]", "GroEL-like equatorial domain superfamily [IPR027413]", "GroES chaperonin superfamily [IPR037124]", "GroES-like superfamily [IPR011032]", "Growth arrest and DNA damage-inducible proteins-interacting protein 1 domain superfamily [IPR043035]", "Growth factor receptor cysteine-rich domain superfamily [IPR009030]", "GrpE nucleotide exchange factor, coiled-coil [IPR013805]", "GrpE nucleotide exchange factor, head [IPR009012]", "Guanylate-binding protein, C-terminal domain superfamily [IPR036543]", "H/ACA RNP complex subunit Gar1/Naf1, Cbf5-binding domain [IPR038664]", "HAD superfamily [IPR023214]", "HAD-like superfamily [IPR036412]", "HAD-superfamily hydrolase, subfamily IA, REG-2-like, capping domain superfamily [IPR044924]", "HBS1-like protein, N-terminal domain superfamily [IPR037189]", "HECT, E3 ligase catalytic domain [IPR035983]", "HIT-like superfamily [IPR036265]", "HIV integrase-binding domain superfamily [IPR036218]", "HR1 repeat superfamily [IPR036274]", "HRDC domain superfamily [IPR044876]", "HRDC-like superfamily [IPR010997]", "HSP20-like chaperone [IPR008978]", "HSP40/DnaJ peptide-binding [IPR008971]", "HSP90, C-terminal domain [IPR037196]", "Haem oxygenase-like, multi-helical [IPR016084]", "Heat shock protein 70kD, C-terminal domain superfamily [IPR029048]", "Heat shock protein 70kD, peptide-binding domain superfamily [IPR029047]", "Heat shock protein DnaJ, cysteine-rich domain superfamily [IPR036410]", "Heavy metal-associated domain superfamily [IPR036163]", "Helix hairpin bin domain superfamily [IPR029012]", "Hemimethylated DNA-binding domain superfamily [IPR036623]", "High mobility group box domain superfamily [IPR036910]", "His-Me finger superfamily [IPR044925]", "Histidine kinase/HSP90-like ATPase superfamily [IPR036890]", "Histidine phosphatase superfamily [IPR029033]", "Histone acetyl transferase 1, N-terminal domain superfamily [IPR037113]", "Histone acetyltransferase HAT1, C-terminal [IPR013523]", "Histone deacetylase domain superfamily [IPR037138]", "Histone-fold [IPR009072]", "Homeobox-like domain superfamily [IPR009057]", "HotDog domain superfamily [IPR029069]", "I/LWEQ domain superfamily [IPR035964]", "ISWI, HAND domain superfamily [IPR036306]", "Immunoglobulin E-set [IPR014756]", "Immunoglobulin-like domain superfamily [IPR036179]", "Immunoglobulin-like fold [IPR013783]", "Importin-alpha, importin-beta-binding domain superfamily [IPR036975]", "Initiation factor 2B-like, C-terminal [IPR042529]", "Inorganic polyphosphate/ATP-NAD kinase, N-terminal [IPR017438]", "Inorganic pyrophosphatase superfamily [IPR036649]", "Inosine triphosphate pyrophosphatase-like [IPR029001]", "Integrase-like, N-terminal [IPR017856]", "Integrin beta tail domain superfamily [IPR036349]", "Integrin domain superfamily [IPR032695]", "Interferon regulatory factor 2-binding protein 1/2, C3HC4-type RING finger superfamily [IPR044882]", "Invasin/intimin cell-adhesion fragments [IPR008964]", "Isochorismatase-like superfamily [IPR036380]", "Isopenicillin N synthase-like superfamily [IPR027443]", "Isoprenoid synthase domain superfamily [IPR008949]", "K Homology domain, type 1 superfamily [IPR036612]", "K homology domain superfamily, prokaryotic type [IPR009019]", "K homology domain-like, alpha/beta [IPR015946]", "KA1 domain/Ssp2, C-terminal [IPR028375]", "Kelch-type beta propeller [IPR015915]", "Kinesin motor domain superfamily [IPR036961]", "Kinesin-like protein Kif23, Arf6-interacting domain superfamily [IPR038105]", "Kringle-like fold [IPR013806]", "Ku, C-terminal domain superfamily [IPR036494]", "Ku70, bridge and pillars domain superfamily [IPR027388]", "L-Aspartase-like [IPR008948]", "L21-like superfamily [IPR036164]", "L27 domain superfamily [IPR036892]", "L28p-like [IPR034704]", "LAP1C-like, C-terminal domain superfamily [IPR038599]", "LDL receptor-like superfamily [IPR036055]", "LEM/LEM-like domain superfamily [IPR011015]", "LIS1, N-terminal [IPR037190]", "LSM domain superfamily [IPR010920]", "Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal [IPR015955]", "Lambda repressor-like, DNA-binding domain superfamily [IPR010982]", "Lamin tail domain superfamily [IPR036415]", "Leucine-rich repeat domain superfamily [IPR032675]", "LexA/Signal peptidase-like superfamily [IPR036286]", "Longin-like domain superfamily [IPR011012]", "MAGE homology domain, winged helix WH1 motif [IPR041898]", "MAGE homology domain, winged helix WH2 motif [IPR041899]", "MAN1, winged-helix domain [IPR041885]", "MFS transporter superfamily [IPR036259]", "MHC class I-like antigen recognition-like superfamily [IPR037055]", "MHC classes I/II-like antigen recognition protein [IPR011162]", "MIT domain superfamily [IPR036181]", "MRG, C-terminal domain superfamily [IPR038217]", "Macro domain-like [IPR043472]", "Malic enzyme, N-terminal domain superfamily [IPR037062]", "Malonyl-CoA ACP transacylase, ACP-binding [IPR016036]", "Manganese/iron superoxide dismutase, C-terminal domain superfamily [IPR036314]", "Manganese/iron superoxide dismutase, N-terminal domain superfamily [IPR036324]", "Mannose-6-phosphate receptor binding domain superfamily [IPR009011]", "Mediator complex subunit 25, PTOV domain superfamily [IPR038196]", "Membrane associated eicosanoid/glutathione metabolism-like domain superfamily [IPR023352]", "Metal-dependent hydrolase [IPR032466]", "Metal-dependent hydrolase, composite domain superfamily [IPR011059]", "Metallo-dependent phosphatase-like [IPR029052]", "Metalloenzyme, LuxS/M16 peptidase-like [IPR011249]", "Metallopeptidase, catalytic domain superfamily [IPR024079]", "Methionyl-tRNA synthetase, Zn-domain [IPR029038]", "Methylglyoxal synthase-like domain superfamily [IPR036914]", "Methylpurine-DNA glycosylase superfamily [IPR036995]", "Methylthioribose-1-phosphate isomerase, N-terminal [IPR027363]", "Methylthiotransferase, N-terminal domain superfamily [IPR038135]", "Mib/herc2 domain superfamily [IPR037252]", "MitoNEET, CDGSH iron-sulfur domain [IPR042216]", "Mitochondrial carrier domain superfamily [IPR023395]", "Mitochondrial cytochrome c oxidase subunit VIc/VIIs superfamily [IPR037169]", "Mitochondrial glycoprotein superfamily [IPR036561]", "Mitochondrial outer membrane translocase complex, Tom20 domain superfamily [IPR023392]", "Moesin tail domain superfamily [IPR008954]", "Mre11, capping domain [IPR038487]", "Mss4-like superfamily [IPR011057]", "Mss4/translationally controlled tumour-associated TCTP [IPR011323]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain superfamily [IPR042179]", "MutS, connector domain superfamily [IPR036678]", "Myosin S1 fragment, N-terminal [IPR008989]", "NAC A/B domain superfamily [IPR038187]", "NAD kinase/diacylglycerol kinase-like domain superfamily [IPR016064]", "NAD(P)-binding domain superfamily [IPR036291]", "NADH-quinone oxidoreductase subunit E, N-terminal [IPR041921]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily [IPR037225]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily [IPR037207]", "NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily [IPR037232]", "NADP-dependent oxidoreductase domain superfamily [IPR036812]", "NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamily [IPR023173]", "NAP-like superfamily [IPR037231]", "NET domain superfamily [IPR038336]", "NO signalling/Golgi transport ligand-binding domain superfamily [IPR024096]", "NSFL1 cofactor p47, SEP domain superfamily [IPR036241]", "NTF2-like domain superfamily [IPR032710]", "NUDIX hydrolase-like domain superfamily [IPR015797]", "NVL2, N-terminal domain superfamily [IPR038100]", "NagB/RpiA transferase-like [IPR037171]", "Neurolysin/Thimet oligopeptidase, N-terminal [IPR024080]", "Neurolysin/Thimet oligopeptidase, domain 2 [IPR024077]", "Nibrin, second BRCT domain superfamily [IPR043014]", "Nicotinate phosphoribosyltransferase-like, C-terminal [IPR036068]", "Nitrogen regulatory PII-like, alpha/beta [IPR011322]", "Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal [IPR015867]", "Nitrous oxide reductase, N-terminal [IPR011045]", "Nop domain superfamily [IPR036070]", "Nop, C-terminal domain [IPR042239]", "Nucleic acid-binding, OB-fold [IPR012340]", "Nucleophile aminohydrolases, N-terminal [IPR029055]", "Nucleoplasmin core domain superfamily [IPR036824]", "Nucleoporin, Nup155-like, C-terminal, subdomain 1 [IPR042533]", "Nucleoporin, Nup155-like, C-terminal, subdomain 2 [IPR042537]", "Nucleoporin, Nup155-like, C-terminal, subdomain 3 [IPR042538]", "Nucleoside diphosphate kinase-like domain superfamily [IPR036850]", "Nucleoside phosphorylase superfamily [IPR035994]", "Nucleotide-binding alpha-beta plait domain superfamily [IPR012677]", "Nucleotide-diphospho-sugar transferases [IPR029044]", "Nucleotidyltransferase superfamily [IPR043519]", "Nucleotidyltransferase, class I-like, C-terminal [IPR011068]", "Nuf2, N-terminal domain superfamily [IPR038275]", "NusG, N-terminal domain superfamily [IPR036735]", "Oxygen-dependent coproporphyrinogen III oxidase superfamily [IPR036406]", "Oxysterol-binding protein superfamily [IPR037239]", "P-loop containing nucleoside triphosphate hydrolase [IPR027417]", "P-type ATPase, A domain superfamily [IPR008250]", "P-type ATPase, cytoplasmic domain N [IPR023299]", "P-type ATPase, transmembrane domain superfamily [IPR023298]", "P-type trefoil domain superfamily [IPR044913]", "PABC (PABP) domain [IPR036053]", "PADR1 domain superfamily [IPR038650]", "PAS domain superfamily [IPR035965]", "PAZ domain superfamily [IPR036085]", "PBDC1-like domain superfamily [IPR023139]", "PDCD5-like superfamily [IPR036883]", "PDZ superfamily [IPR036034]", "PEBP-like superfamily [IPR036610]", "PH-like domain superfamily [IPR011993]", "PIN-like domain superfamily [IPR029060]", "PITH domain superfamily [IPR037047]", "PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily [IPR017946]", "PNPase/RNase PH domain superfamily [IPR027408]", "POLO box domain superfamily [IPR036947]", "PPM-type phosphatase domain superfamily [IPR036457]", "PRP4-like superfamily [IPR036285]", "PTPA superfamily [IPR037218]", "PUA domain superfamily [IPR036974]", "PUA-like superfamily [IPR015947]", "PWI domain superfamily [IPR036483]", "PX domain superfamily [IPR036871]", "Paired amphipathic helix superfamily [IPR036600]", "PapD-like superfamily [IPR008962]", "Papain-like cysteine peptidase superfamily [IPR038765]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase superfamily [IPR036959]", "Peptidase C65, otubain, subdomain 2 [IPR042467]", "Peptidase C65, otubain, subdomain 1 [IPR042468]", "Peptidase M1, LTA-4 hydrolase/aminopeptidase, C-terminal domain superfamily [IPR038502]", "Peptidase M13, domain 2 [IPR042089]", "Peptidase M4/M1, CTD superfamily [IPR027268]", "Peptidase M41-like [IPR037219]", "Peptidase M60, enhancin-like domain 3 [IPR042279]", "Peptidase S59, nucleoporin superfamily [IPR036903]", "Peptidase S8/S53 domain superfamily [IPR036852]", "Peptidyl-tRNA hydrolase II domain superfamily [IPR023476]", "Pex19, C-terminal domain superfamily [IPR038322]", "Phenylalanyl-tRNA synthetase-like, B3/B4 [IPR020825]", "Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily [IPR036940]", "Phosphoenolpyruvate carboxykinase, C-terminal [IPR013035]", "Phosphoenolpyruvate carboxykinase, N-terminal [IPR008210]", "Phosphofructokinase superfamily [IPR035966]", "Phosphoglucose isomerase, C-terminal [IPR023096]", "Phosphoglycerate kinase superfamily [IPR036043]", "Phosphoglycerate kinase, N-terminal [IPR015824]", "Phosphoglycolate phosphatase-like, domain 2 [IPR023198]", "Phosphoinositide 3-kinase, accessory (PIK) domain superfamily [IPR042236]", "Phospholipase B-like, domain 1 [IPR043040]", "Phospholipase B-like, domain 2 [IPR043041]", "Phospholipase B-like, domain 3 [IPR043042]", "Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily [IPR036604]", "Phosphoribosylglycinamide synthetase, C-domain superfamily [IPR037123]", "Phosphoribosyltransferase-like [IPR029057]", "Phosphorylated adapter RNA export protein, RNA-binding domain superfamily [IPR038092]", "Phosphotyrosine protein phosphatase I superfamily [IPR036196]", "Phosphotyrosyl phosphatase activator, C-terminal lid domain [IPR043170]", "Plakin repeat superfamily [IPR035915]", "Poly(ADP-ribose) polymerase, regulatory domain superfamily [IPR036616]", "Polyketide synthase, dehydratase domain superfamily [IPR042104]", "Polymerase/histidinol phosphatase-like [IPR016195]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain superfamily [IPR036456]", "Porin domain superfamily [IPR023614]", "Pre-ATP-grasp domain superfamily [IPR016185]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding domain superfamily [IPR042516]", "Pre-mRNA-splicing factor Isy1 superfamily [IPR037200]", "Prefoldin [IPR009053]", "Profilin superfamily [IPR036140]", "Prolyl-tRNA synthetase, class II [IPR017449]", "Proteasomal ubiquitin receptor Rpn13/ADRM1, Pru domain superfamily [IPR038633]", "Proteasome activator PA28, C-terminal domain superfamily [IPR036997]", "Proteasome activator PA28, N-terminal domain superfamily [IPR036996]", "Proteasome activator superfamily [IPR036252]", "Proteasome assembly chaperone 2 superfamily [IPR038389]", "Protein arginine methyltransferase NDUFAF7 superfamily [IPR038375]", "Protein kinase-like domain superfamily [IPR011009]", "Protein-tyrosine phosphatase-like [IPR029021]", "Prp8 RNase domain IV, fingers region [IPR043173]", "Prp8 RNase domain IV, palm region [IPR043172]", "Pseudouridine synthase I, TruA, C-terminal [IPR020095]", "Pseudouridine synthase TruA/RsuA/RluB/E/F, N-terminal [IPR020094]", "Pseudouridine synthase, TruD, catalytic domain [IPR042214]", "Pseudouridine synthase, catalytic domain superfamily [IPR020103]", "Pterin 4 alpha carbinolamine dehydratase superfamily [IPR036428]", "PurM-like, C-terminal domain superfamily [IPR036676]", "PurM-like, N-terminal domain superfamily [IPR036921]", "Putative DNA-binding domain superfamily [IPR009061]", "Pyridoxal phosphate-dependent transferase [IPR015424]", "Pyridoxal phosphate-dependent transferase, major domain [IPR015421]", "Pyridoxal phosphate-dependent transferase, small domain [IPR015422]", "Pyruvate kinase, C-terminal domain superfamily [IPR036918]", "Pyruvate kinase, insert domain superfamily [IPR015806]", "Pyruvate kinase-like domain superfamily [IPR040442]", "Pyruvate kinase-like, insert domain superfamily [IPR011037]", "Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily [IPR015813]", "Queuine tRNA-ribosyltransferase-like [IPR036511]", "Quinoprotein alcohol dehydrogenase-like superfamily [IPR011047]", "Quinoprotein amine dehydrogenase, beta chain-like [IPR011044]", "R3H domain superfamily [IPR036867]", "RAP domain superfamily [IPR036744]", "RGS domain superfamily [IPR036305]", "RGS, subdomain 2 [IPR044926]", "RNA 3'-terminal phosphate cyclase domain superfamily [IPR037136]", "RNA 3'-terminal phosphate cyclase, insert domain superfamily [IPR036553]", "RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta [IPR013792]", "RNA polymerase Rpb1, clamp domain superfamily [IPR044893]", "RNA polymerase Rpb1, domain 3 superfamily [IPR042102]", "RNA polymerase Rpb1, domain 7 superfamily [IPR038593]", "RNA polymerase Rpb1, funnel domain superfamily [IPR038120]", "RNA polymerase Rpb2, OB-fold [IPR014724]", "RNA polymerase Rpb2, domain 2 superfamily [IPR037034]", "RNA polymerase Rpb5, N-terminal domain superfamily [IPR036710]", "RNA polymerase Rpb7-like, N-terminal domain superfamily [IPR036898]", "RNA polymerase subunit RPB10 [IPR023580]", "RNA polymerase, RBP11-like subunit [IPR036603]", "RNA-binding S4 domain superfamily [IPR036986]", "RNA-binding domain superfamily [IPR035979]", "RPB5-like RNA polymerase subunit superfamily [IPR035913]", "RPN13, DEUBAD domain superfamily [IPR038108]", "RRF superfamily [IPR036191]", "RUN domain superfamily [IPR037213]", "Rab geranylgeranyltransferase, alpha subunit, insert-domain superfamily [IPR036254]", "Rab-GTPase-TBC domain superfamily [IPR035969]", "Radical SAM, alpha/beta horseshoe [IPR023404]", "Ran-GTPase activating protein 1, C-terminal domain superfamily [IPR036720]", "Rap/Ran-GAP superfamily [IPR035974]", "Ras guanine nucleotide exchange factor domain superfamily [IPR023578]", "Ras guanine-nucleotide exchange factor, catalytic domain superfamily [IPR036964]", "Receptor L-domain superfamily [IPR036941]", "Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II [IPR009091]", "Regulatory factor, effector binding domain superfamily [IPR011256]", "Rho GDP-dissociation inhibitor domain superfamily [IPR024792]", "Rho GTPase activation protein [IPR008936]", "Rhodanese-like domain superfamily [IPR036873]", "Rhomboid-like superfamily [IPR035952]", "Riboflavin synthase-like beta-barrel [IPR017938]", "Ribokinase-like [IPR029056]", "Ribonuclease H superfamily [IPR036397]", "Ribonuclease H-like superfamily [IPR012337]", "Ribonuclease H1, N-terminal domain superfamily [IPR037056]", "Ribonuclease HII, helix-loop-helix cap domain superfamily [IPR023160]", "Ribonuclease III, endonuclease domain superfamily [IPR036389]", "Ribonuclease T2-like superfamily [IPR036430]", "Ribonuclease Z/Hydroxyacylglutathione hydrolase-like [IPR036866]", "Ribonucleotide reductase R1 subunit, N-terminal [IPR008926]", "Ribonucleotide reductase-like [IPR012348]", "Ribosomal L15/L27a, N-terminal [IPR027386]", "Ribosomal L18e/L15P superfamily [IPR036227]", "Ribosomal RNA-processing protein 8, N-terminal domain [IPR042036]", "Ribosomal protein L1, 3-layer alpha/beta-sandwich [IPR016095]", "Ribosomal protein L1-like [IPR023674]", "Ribosomal protein L10-like domain superfamily [IPR043141]", "Ribosomal protein L10e/L16 superfamily [IPR036920]", "Ribosomal protein L11, C-terminal domain superfamily [IPR036769]", "Ribosomal protein L11/L12, N-terminal domain superfamily [IPR036796]", "Ribosomal protein L13 superfamily [IPR036899]", "Ribosomal protein L14 superfamily [IPR036853]", "Ribosomal protein L15e core domain superfamily [IPR024794]", "Ribosomal protein L17 superfamily [IPR036373]", "Ribosomal protein L19 superfamily [IPR038657]", "Ribosomal protein L19/L19e superfamily [IPR035970]", "Ribosomal protein L19/L19e, domain 1 [IPR015972]", "Ribosomal protein L2, domain 2 [IPR014722]", "Ribosomal protein L2, domain 3 [IPR014726]", "Ribosomal protein L21 superfamily [IPR036948]", "Ribosomal protein L22/L17 superfamily [IPR036394]", "Ribosomal protein L22e superfamily [IPR038526]", "Ribosomal protein L23/L15e core domain superfamily [IPR012678]", "Ribosomal protein L24e/L24 superfamily [IPR038630]", "Ribosomal protein L25/Gln-tRNA synthetase, N-terminal [IPR020056]", "Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily [IPR011035]", "Ribosomal protein L27e superfamily [IPR038655]", "Ribosomal protein L28/L24 superfamily [IPR037147]", "Ribosomal protein L29/L35 superfamily [IPR036049]", "Ribosomal protein L3, domain 3, archaeal type superfamily [IPR044892]", "Ribosomal protein L30, ferredoxin-like fold domain superfamily [IPR036919]", "Ribosomal protein L31e domain superfamily [IPR023621]", "Ribosomal protein L32e superfamily [IPR036351]", "Ribosomal protein L35A superfamily [IPR038661]", "Ribosomal protein L36e domain superfamily [IPR038097]", "Ribosomal protein L37ae/L37e [IPR011331]", "Ribosomal protein L38e superfamily [IPR038464]", "Ribosomal protein L4 domain superfamily [IPR023574]", "Ribosomal protein L5 domain superfamily [IPR022803]", "Ribosomal protein L6, alpha-beta domain superfamily [IPR036789]", "Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like [IPR014719]", "Ribosomal protein L7/L12, oligomerisation domain superfamily [IPR036235]", "Ribosomal protein L9, N-terminal domain superfamily [IPR036935]", "Ribosomal protein L9/RNase H1, N-terminal [IPR009027]", "Ribosomal protein P1/P2, N-terminal domain [IPR038716]", "Ribosomal protein S10 domain superfamily [IPR036838]", "Ribosomal protein S11 superfamily [IPR036967]", "Ribosomal protein S13-like, H2TH [IPR010979]", "Ribosomal protein S17e-like superfamily [IPR036401]", "Ribosomal protein S19/S15, superfamily [IPR023575]", "Ribosomal protein S2, flavodoxin-like domain superfamily [IPR023591]", "Ribosomal protein S21e superfamily [IPR038579]", "Ribosomal protein S26e superfamily [IPR038551]", "Ribosomal protein S3, C-terminal domain superfamily [IPR036419]", "Ribosomal protein S4e, central domain superfamily [IPR038237]", "Ribosomal protein S5 domain 2-type fold [IPR020568]", "Ribosomal protein S5 domain 2-type fold, subgroup [IPR014721]", "Ribosomal protein S7 domain superfamily [IPR036823]", "Ribosomal protein S8 superfamily [IPR035987]", "Ribosomal protein S8e subdomain, eukaryotes [IPR042563]", "Ribosome maturation protein SBDS, N-terminal domain superfamily [IPR036786]", "Ribosome maturation protein Sdo1/SBDS, central domain superfamily [IPR037188]", "Ribulose-phosphate binding barrel [IPR011060]", "Ricin B-like lectins [IPR035992]", "RmlC-like cupin domain superfamily [IPR011051]", "RmlC-like jelly roll fold [IPR014710]", "Rossmann-like alpha/beta/alpha sandwich fold [IPR014729]", "Rudiment single hybrid motif [IPR011054]", "RutC-like superfamily [IPR035959]", "RuvA domain 2-like [IPR010994]", "RuvBL1/2, DNA/RNA binding domain [IPR042487]", "S-adenosyl-L-methionine-dependent methyltransferase [IPR029063]", "S-adenosylmethionine synthetase superfamily [IPR022636]", "S15/NS1, RNA-binding [IPR009068]", "SAP domain superfamily [IPR036361]", "SCP2 sterol-binding domain superfamily [IPR036527]", "SGNH hydrolase superfamily [IPR036514]", "SH2 domain superfamily [IPR036860]", "SH3-like domain superfamily [IPR036028]", "SKP1-like, dimerisation domain superfamily [IPR036296]", "SKP1/BTB/POZ domain superfamily [IPR011333]", "SLED domain superfamily [IPR038348]", "SMAD/FHA domain superfamily [IPR008984]", "SMCs flexible hinge superfamily [IPR036277]", "SNARE [IPR010989]", "SNF2-like, N-terminal domain superfamily [IPR038718]", "SNase-like, OB-fold superfamily [IPR035437]", "SPOC-like, C-terminal domain superfamily [IPR016194]", "SRA-YDG superfamily [IPR036987]", "SRCR-like domain superfamily [IPR036772]", "SRP/SRP receptor, N-terminal [IPR036225]", "SRP68, N-terminal domain superfamily [IPR038253]", "SSRP1 domain superfamily [IPR038167]", "START-like domain superfamily [IPR023393]", "STAT transcription factor, DNA-binding, N-terminal [IPR012345]", "STAT transcription factor, N-terminal domain superfamily [IPR036535]", "STAT transcription factor, coiled coil [IPR015988]", "STAT1, C-terminal domain superfamily [IPR038295]", "SUI1 domain superfamily [IPR036877]", "SWAP/Surp superfamily [IPR035967]", "SWIB/MDM2 domain superfamily [IPR036885]", "Saposin-like [IPR011001]", "Scavenger mRNA decapping enzyme, N-terminal [IPR011145]", "Schlafen, AlbA_2 domain superfamily [IPR038461]", "ScpA-like, C-terminal [IPR023093]", "Sec1-like superfamily [IPR036045]", "Sec1-like, domain 1 [IPR043154]", "Sec1-like, domain 2 [IPR027482]", "Sec1-like, domain 3a [IPR043127]", "Sec23/Sec24 helical domain superfamily [IPR036175]", "Sec7 domain superfamily [IPR035999]", "Sec7, C-terminal domain superfamily [IPR023394]", "SecY domain superfamily [IPR023201]", "Secretoglobin superfamily [IPR035960]", "Serine carboxypeptidase S28, SKS domain [IPR042269]", "Serine-tRNA synthetase, type1, N-terminal domain superfamily [IPR042103]", "Serpin superfamily [IPR036186]", "Serpin superfamily, domain 1 [IPR042178]", "Serpin superfamily, domain 2 [IPR042185]", "Signal recognition particle SRP54, N-terminal domain superfamily [IPR042101]", "Signal recognition particle, SRP54 subunit, M-domain superfamily [IPR036891]", "Signal recognition particle, SRP9/SRP14 subunit [IPR009018]", "Sin3 associated polypeptide p18 superfamily [IPR042534]", "Single hybrid motif [IPR011053]", "Sirtuin, catalytic core small domain superfamily [IPR026591]", "Six-bladed beta-propeller, TolB-like [IPR011042]", "Six-hairpin glycosidase superfamily [IPR008928]", "Six-hairpin glycosidase-like superfamily [IPR012341]", "Smac/DIABLO-like superfamily [IPR009062]", "Sodium/potassium-transporting ATPase subunit beta superfamily [IPR038702]", "Sodium:dicarboxylate symporter superfamily [IPR036458]", "Spermidine synthase, tetramerisation domain superfamily [IPR037163]", "Spt6, Death-like domain [IPR042066]", "Stathmin superfamily [IPR036002]", "Sterile alpha motif/pointed domain superfamily [IPR013761]", "Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily [IPR027477]", "Succinyl-CoA synthetase-like [IPR016102]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain superfamily [IPR042568]", "TAP42/TAP46-like superfamily [IPR038511]", "TBP domain superfamily [IPR012295]", "TCP-1-like chaperonin intermediate domain superfamily [IPR027410]", "TEL2, C-terminal domain superfamily [IPR038528]", "TFIIIC, subcomplex tauA subunit Sfc1, triple barrel domain superfamily [IPR042536]", "TFIIS/LEDGF domain superfamily [IPR035441]", "TGS-like [IPR012676]", "TGS-like domain superfamily [IPR023192]", "TMEM14 superfamily [IPR044890]", "TRAF-like [IPR008974]", "TRF2-interacting telomeric protein/Rap1, C-terminal domain superfamily [IPR038104]", "TROVE domain superfamily [IPR037214]", "Talin, central domain superfamily [IPR036476]", "Tautomerase/MIF superfamily [IPR014347]", "Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid [IPR008930]", "Tetraspanin, EC2 domain superfamily [IPR008952]", "Tetratricopeptide-like helical domain superfamily [IPR011990]", "Tex-like domain superfamily [IPR023323]", "Tex-like protein, HTH domain superfamily [IPR023319]", "Thiamin diphosphate-binding fold [IPR029061]", "Thiolase-like [IPR016039]", "Thioredoxin-like superfamily [IPR036249]", "Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily [IPR018163]", "Thymidylate synthase/dCMP hydroxymethylase superfamily [IPR036926]", "Tim10-like domain superfamily [IPR035427]", "Tma16 superfamily [IPR038356]", "Transcription elongation factor S-II, central domain superfamily [IPR036575]", "Transcription factor EnY2 superfamily [IPR038212]", "Transcription termination and cleavage factor, C-terminal domain superfamily [IPR038192]", "Transcriptional regulator TACO1-like, domain 3 [IPR026564]", "Transferrin receptor-like, dimerisation domain superfamily [IPR036757]", "Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II [IPR009014]", "Translation Initiation factor eIF- 4e-like [IPR023398]", "Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal [IPR009001]", "Translation elongation factor EF1B/ribosomal protein S6 [IPR014717]", "Translation elongation factor eEF-1beta-like superfamily [IPR036219]", "Translation initiation factor 2, alpha subunit, C-terminal [IPR024055]", "Translation initiation factor 2, alpha subunit, middle domain superfamily [IPR024054]", "Translation initiation factor 3, subunit 12, N-terminal, eukaryotic [IPR016020]", "Translation initiation factor IF-2, domain 3 superfamily [IPR036925]", "Translation initiation factor IF2/IF5, N-terminal [IPR016189]", "Translation initiation factor IF2/IF5, zinc-binding [IPR016190]", "Translation initiation factor eIF-2B subunit alpha, N-terminal [IPR042528]", "Translation protein SH3-like domain superfamily [IPR008991]", "Translation protein, beta-barrel domain superfamily [IPR009000]", "Translin superfamily [IPR036081]", "Translin, C-terminal [IPR016069]", "Translin, N-terminal [IPR016068]", "Trimeric LpxA-like superfamily [IPR011004]", "Triosephosphate isomerase superfamily [IPR035990]", "Tubulin binding cofactor A superfamily [IPR036126]", "Tubulin, C-terminal [IPR023123]", "Tubulin/FtsZ, C-terminal [IPR008280]", "Tubulin/FtsZ, GTPase domain superfamily [IPR036525]", "Tubulin/FtsZ-like, C-terminal domain [IPR037103]", "UBA-like superfamily [IPR009060]", "UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily [IPR036220]", "UROD/MetE-like superfamily [IPR038071]", "Ubiquitin activating enzyme, alpha domain superfamily [IPR023318]", "Ubiquitin-activating enzyme E1, C-terminal domain superfamily [IPR038252]", "Ubiquitin-activating enzyme E1, FCCH domain superfamily [IPR042302]", "Ubiquitin-activating enzyme E1, SCCH domain [IPR042063]", "Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1 [IPR042449]", "Ubiquitin-activating enzyme [IPR035985]", "Ubiquitin-conjugating enzyme/RWD-like [IPR016135]", "Ubiquitin-like domain superfamily [IPR029071]", "Ufd1-like, Nn domain [IPR042299]", "Uracil-DNA glycosylase-like domain superfamily [IPR036895]", "Ureohydrolase domain superfamily [IPR023696]", "V-type ATP synthase c/d subunit, domain 3 superfamily [IPR044911]", "V-type ATP synthase subunit c/d subunit superfamily [IPR036079]", "V-type ATPase subunit C/d [IPR035067]", "V-type ATPase subunit E, C-terminal domain superfamily [IPR038495]", "VPS9 domain superfamily [IPR037191]", "Vacuolar ATP synthase subunit C superfamily [IPR036132]", "Vacuolar protein sorting-associated protein 33, domain 3b [IPR043155]", "Vacuolar protein sorting-associated protein 35, C-terminal [IPR042491]", "Vacuolar protein sorting-associated protein IST1-like [IPR042277]", "Valyl-tRNA synthetase, tRNA-binding arm superfamily [IPR037118]", "Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain [IPR009008]", "Vanillyl-alcohol oxidase, C-terminal subdomain 2 [IPR016171]", "Vps53, C-terminal domain superfamily [IPR038260]", "WD40-repeat-containing domain superfamily [IPR036322]", "WD40/YVTN repeat-like-containing domain superfamily [IPR015943]", "WGR domain superfamily [IPR036930]", "WW domain superfamily [IPR036020]", "WWE domain superfamily [IPR037197]", "Winged helix DNA-binding domain superfamily [IPR036390]", "Winged helix-like DNA-binding domain superfamily [IPR036388]", "XPC-binding domain superfamily [IPR036353]", "YebC-like [IPR029072]", "YjeF N-terminal domain superfamily [IPR036652]", "YqgF/RNase H-like domain superfamily [IPR037027]", "ZPR1, A/B domain [IPR042451]", "ZPR1, zinc finger domain [IPR042452]", "Zinc finger C2H2 superfamily [IPR036236]", "Zinc finger, C2H2C-type superfamily [IPR036060]", "Zinc finger, CCCH-type superfamily [IPR036855]", "Zinc finger, CCHC-type superfamily [IPR036875]", "Zinc finger, FYVE/PHD-type [IPR011011]", "Zinc finger, NHR/GATA-type [IPR013088]", "Zinc finger, PARP-type superfamily [IPR036957]", "Zinc finger, RING/FYVE/PHD-type [IPR013083]", "Zinc finger, RanBP2-type superfamily [IPR036443]", "Zinc finger, Sec23/Sec24-type superfamily [IPR036174]", "Zinc finger, ZZ-type superfamily [IPR043145]", "Zinc-binding ribosomal protein [IPR011332]", "dUTPase-like superfamily [IPR036157]", "eRF1, domain 1 [IPR024049]", "eRF1, domain 2 superfamily [IPR042226]", "p53-like tetramerisation domain superfamily [IPR036674]", "p53-like transcription factor, DNA-binding [IPR008967]", "p53/RUNT-type transcription factor, DNA-binding domain superfamily [IPR012346]", "ssDNA-binding transcriptional regulator [IPR009044]", "tRNA (guanine-N1-)-methyltransferase, N-terminal [IPR029026]", "tRNA methyltransferase TRM10-type domain superfamily [IPR038459]", "tRNA-splicing ligase RtcB-like superfamily [IPR036025]", "von Willebrand factor A-like domain superfamily [IPR036465]"], "available_proteins": ["AAAS", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "ABCB1", "ABCB10", "ABCB7", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAP2", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADH5", "ADI1", "ADK", "ADNP", "ADO", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP17A", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALKBH5", "ALYREF", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANKRD28", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP3B1", "AP3D1", "AP3M1", "APEH", "APEX1", "API5", "APMAP", "APRT", "AQR", "ARCN1", "ARF4", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL8B", "ARMC1", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "AS3MT", "ASCC2", "ASCC3", "ASNA1", "ASNS", "ASPH", "ASPM", "ASRGL1", "ATAD1", "ATAD3A", "ATAD3B", "ATAD5", "ATG4B", "ATIC", "ATL2", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5H", "ATP5O", "ATP6", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP6V1H", "ATP7B", "ATRX", "ATXN10", "BABAM1", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAK1", "BANF1", "BAP18", "BAX", "BAZ1A", "BAZ1B", "BCAT2", "BCL10", "BCL2L12", "BCL2L13", "BCS1L", "BIRC6", "BLMH", "BLVRA", "BLVRB", "BMS1", "BOP1", "BRD2", "BSG", "BTF3", "BUB3", "BZW1", "BZW2", "C1QBP", "C2CD2", "C2CD5", "CAB39", "CACUL1", "CACYBP", "CAD", "CALR", "CALU", "CAND1", "CANX", "CAP1", "CAPN1", "CAPZA1", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP2", "CASP3", "CASP6", "CBFB", "CBR1", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD276", "CD2AP", "CD2BP2", "CD47", "CD81", "CDC23", "CDC27", "CDC37", "CDC42", "CDC5L", "CDC73", "CDK1", "CDK13", "CDK2", "CDK4", "CDK6", "CDKAL1", "CDKN2A", "CEBPZ", "CELF1", "CELF2", "CENPV", "CEP170", "CERS2", "CFL1", "CFL2", "CHAC2", "CHAF1B", "CHAMP1", "CHD1", "CHD1L", "CHD4", "CHEK2", "CHERP", "CHID1", "CHKA", "CHORDC1", "CHRAC1", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CIZ1", "CKAP5", "CKB", "CKMT1A*", "CLASP2", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLNS1A", "CLP1", "CLPB", "CLPP", "CLPX", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNN2", "CNN3", "CNOT1", "CNOT7", "CNOT9", "CNP", "COA7", "COASY", "COL4A3BP", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPZ1", "CORO1C", "COTL1", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZL1", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWC22", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYP20A1", "CYP51A1", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DCAF13", "DCAF7", "DCAKD", "DCPS", "DCTN1", "DCXR", "DDB1", "DDI2", "DDRGK1", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHFR", "DHPS", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX40", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIP2B", "DIS3", "DIS3L2", "DKC1", "DLAT", "DLD", "DLST", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1", "DNM1L", "DNM2", "DNMT1", "DOHH", "DPF2", "DPH2", "DPM1", "DPP9", "DPYSL2", "DPYSL3", "DRG1", "DRG2", "DSG2", "DSP", "DST", "DSTN", "DTL", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC3", "EDC4", "EDF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFL1", "EFTUD2", "EHD1", "EHMT1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3B", "EIF3E", "EIF3G", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELMO2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC7", "EMD", "EMG1", "EML4", "ENDOD1", "ENO1", "ENOPH1", "ENY2", "EPB41", "EPB41L2", "EPB41L3", "EPHX1", "EPHX2", "EPPK1", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERC1", "ERCC2", "ERCC6L", "ERH", "ERI1", "ERLIN2", "ERO1A", "ERP29", "ERP44", "ESD", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC6", "EXOC7", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EYA3", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAHD2A", "FAM120A", "FAM120B", "FAR1", "FARSA", "FARSB", "FASN", "FBL", "FBXO22", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FH", "FHOD1", "FKBP10", "FKBP14", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FLCN", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNBP4", "FNDC3A", "FNTB", "FOXC1", "FOXRED1", "FRG1", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2B", "GBA", "GBF1", "GCAT", "GCDH", "GCLM", "GCN1", "GDI1", "GDI2", "GDPD1", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GIGYF2", "GINS1", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLTP", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GNS", "GOPC", "GOT1", "GOT2", "GPD2", "GPI", "GPKOW", "GPS1", "GPT2", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2E1", "GTF2I", "GTF3C2", "GTF3C3", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP4", "GUSB", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGFL2", "HDHD2", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEBP1", "HECTD1", "HELLS", "HELZ", "HERC2", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HP1BP3", "HPRT1", "HS1BP3", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDE", "IDI1", "IFIT5", "IFT27", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "ILF2", "ILF3", "ILKAP", "ILVBL", "IMP3", "IMPDH2", "INF2", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IRF2BPL", "IRS4", "ISOC1", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "IVD", "JUP", "KARS", "KAT7", "KCTD12", "KCTD5", "KDELC2", "KDM1A", "KDM1B", "KDSR", "KHDRBS1", "KHSRP", "KIAA0368", "KIF11", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KLC1", "KLC2", "KLC4", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRR1", "KYAT3", "L2HGDH", "LANCL1", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LDAH", "LDHA", "LDHB", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LPCAT1", "LRBA", "LRCH2", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC59", "LRWD1", "LSG1", "LSM14A", "LSM14B", "LSM2", "LSM6", "LSS", "LTA4H", "LTN1", "LYAR", "LYPLA1", "M6PR", "MACF1", "MAGED2", "MANF", "MAP2K1", "MAP2K2", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARK2", "MARS", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MCAT", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED25", "MEPCE", "METTL1", "METTL13", "MFN2", "MFSD10", "MFSD5", "MGEA5", "MGST2", "MGST3", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MIPEP", "MKI67", "MMAB", "MMS19", "MOGS", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPG", "MPI", "MPP2", "MPP6", "MPRIP", "MPST", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL28", "MRPL3", "MRPL38", "MRPL39", "MRPL44", "MRPL45", "MRPL46", "MRPL9", "MRPS10", "MRPS15", "MRPS17", "MRPS2", "MRPS25", "MRPS27", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTX1", "MTX2", "MTX3", "MUT", "MVD", "MVK", "MYBBP1A", "MYEF2", "MYH10", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA25", "NAA40", "NAA50", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCBP1", "NCDN", "NCK1", "NCL", "NCOA5", "NDRG3", "NDUFA10", "NDUFA9", "NDUFAF7", "NDUFS1", "NDUFS3", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4", "NEK9", "NELFE", "NENF", "NFS1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPSNAP2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NME1", "NME2", "NMT1", "NNT", "NOC2L", "NOC3L", "NOC4L", "NOL11", "NOL8", "NOL9", "NOM1", "NONO", "NOP2", "NOP56", "NOP58", "NOSIP", "NOVA2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSUN2", "NSUN5", "NSUN6", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDCD2", "NUDT1", "NUDT12", "NUDT16L1", "NUDT21", "NUDT5", "NUF2", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP98", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "OSBP", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OXSR1", "P3H1", "P4HA1", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAIP1", "PAK1IP1", "PAK2", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PASK", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDS5A", "PDS5B", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF2", "PHF3", "PHF6", "PHGDH", "PHIP", "PICALM", "PIK3C2A", "PIN1", "PIR", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN2", "PLA2G15", "PLBD2", "PLCG1", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PMVK", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPO", "PNPT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLRMT", "PON2", "POR", "PPA1", "PPA2", "PPAT", "PPIB", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R1", "PPP5C", "PPT1", "PPT2", "PQBP1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRKAA1", "PRKACA", "PRKAR1A", "PRKAR2A", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF39", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG2", "PSPC1", "PTBP1", "PTCD3", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTRH2", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PWP1", "PWP2", "PYCR1", "PYCR2", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB21", "RAB24", "RAB34", "RAB35", "RAB39A", "RAB3B", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB8B", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP1GDS1", "RAPGEF2", "RARS", "RASA1", "RAVER1", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM8A", "RBMX", "RBMXL1", "RBP1", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RINT1", "RMDN1", "RMDN3", "RNASEH2A", "RNASET2", "RNF114", "RNF14", "RNF40", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS8", "RPS9", "RPSA", "RREB1", "RRM1", "RRM2", "RRP12", "RRP8", "RRP9", "RSF1", "RSL1D1", "RSU1", "RTCB", "RTN4IP1", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SAE1", "SAFB", "SAFB2", "SAMHD1", "SAP18", "SAR1A", "SARNP", "SARS", "SARS2", "SART3", "SBDS", "SCCPDH", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SDCBP", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEH1L", "SEL1L", "SENP3", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERPINB6", "SERPINH1", "SET", "SF1", "SF3A1", "SF3A2", "SF3B1", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGPL1", "SGTA", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHMT1", "SHMT2", "SHOC2", "SIN3A", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC30A5", "SLC3A2", "SLC4A1AP", "SLC9A3R1", "SLFN11", "SLIRP", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMS", "SMU1", "SMYD3", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNX1", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SOD2", "SON", "SORD", "SPAG9", "SPART", "SPATA5L1", "SPECC1L", "SPEN", "SPOUT1", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "STAG2", "STAM", "STARD3", "STARD7", "STAT1", "STAT3", "STIM2", "STIP1", "STK4", "STMN1", "STOML2", "STRAP", "STRBP", "STRN", "STUB1", "STX10", "STX12", "STX17", "STX4", "STX5", "STX7", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SULT2A1", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNJ2BP", "TAB1", "TACO1", "TAF15", "TAGLN2", "TALDO1", "TARDBP", "TARS", "TARS2", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL2", "TBL3", "TCAF1", "TCEA1", "TCERG1", "TCF25", "TCP1", "TDP2", "TDRKH", "TECR", "TELO2", "TERF2IP", "TEX10", "TEX264", "TFAM", "TFRC", "THOC1", "THOC3", "THOP1", "THUMPD3", "TIA1", "TIAL1", "TIMM13", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TK1", "TKT", "TLN1", "TMA16", "TMED2", "TMED7", "TMEM14C", "TMOD3", "TMPO", "TMPO", "TMPPE", "TMTC3", "TMX1", "TMX2", "TMX4", "TNPO1", "TNPO2", "TOE1", "TOMM20", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOR1AIP2", "TOX4", "TP53", "TP53BP1", "TPD52L2", "TPI1", "TPM4", "TPP1", "TPP2", "TPT1", "TRA2A", "TRA2B", "TRAP1", "TRAPPC4", "TRAPPC5", "TRIM21", "TRIM25", "TRIM27", "TRIM28", "TRIP12", "TRIP13", "TRMT10C", "TRMT11", "TRMT2A", "TROVE2", "TRUB1", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPYL1", "TSTA3", "TTC1", "TTC19", "TTC26", "TTC37", "TTC38", "TTC4", "TTI1", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE2V1", "UBE3C", "UBE4A", "UBLCP1", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UCHL5", "UCK2", "UFC1", "UFD1", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "UROD", "USO1", "USP10", "USP11", "USP14", "USP19", "USP28", "USP33", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VPS26A", "VPS29", "VPS33A", "VPS35", "VPS4A", "VPS51", "VPS53", "VRK1", "VRK3", "WAPL", "WARS", "WDHD1", "WDR1", "WDR18", "WDR3", "WDR33", "WDR36", "WDR41", "WDR43", "WDR46", "WDR5", "WDR6", "WDR61", "WDR70", "WDR73", "WDR75", "WDR77", "WDR82", "WFS1", "WIPI2", "WIZ", "WRAP53", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "YARS", "YARS2", "YBX1", "YKT6", "YME1L1", "YRDC", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H15", "ZC3H18", "ZC3HAV1", "ZCCHC11", "ZCCHC3", "ZDHHC13", "ZFR", "ZFYVE16", "ZNF512", "ZNF512B", "ZNF622", "ZNF638", "ZNF687", "ZPR1", "ZRANB2"], "leading_proteins": ["AARS", "AARS2", "ABCB7", "ABCC1", "ACOX3", "ACTN2", "AKT1", "AKT2", "ANKFY1", "ANKHD1", "ANKLE2", "ANLN", "AP1B1", "AP2A2", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ASCC3", "ASPM", "ATP5A1", "ATP5B", "ATRX", "BAIAP2", "BAP18", "CAB39", "CAP1", "CARS", "CASP3", "CDK13", "CDKN2A", "CERS2", "CHD1L", "CHKA", "CLGN", "CLNS1A", "COASY", "COL4A3BP", "CUL1", "CUL2", "CUL3", "CUL5", "CXADR", "CYP20A1", "DDRGK1", "DIAPH3", "DNAJA3", "DNAJC3", "DNMT1", "DOHH", "DRG2", "EARS2", "EHD1", "EHMT2", "EIF3M", "ELMO2", "ELOC", "EPRS", "ERCC6L", "EXOC2", "FDXR", "FKBP9", "FOXC1", "FXR2", "G3BP1", "GAA", "GARS", "GINS2", "GINS3", "GLOD4", "GNL3L", "H1F0", "H1FX", "H2AFY2", "H4C1*", "HADH", "HGH1", "HIBADH", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HLTF", "HMOX2", "HP1BP3", "HSP90AA1", "HSP90AB1", "HSP90B1", "IGF2BP2", "ILKAP", "IPO11", "IPO8", "JUP", "KCTD12", "KCTD5", "KDM1A", "KDM1B", "KIF1A", "KIF23", "KIF2A", "KIF2C", "KPNA1", "LANCL1", "LANCL2", "LAP3", "LDHB", "LETM1", "LIG1", "LRRC47", "MAP2K2", "MAP3K7", "MARC1", "MARK2", "MDH1", "MDH2", "MEPCE", "MIPEP", "MOGS", "MOSPD2", "MRPL39", "MRPL45", "MRPS17", "MSN", "MTA1", "MTA2", "MTIF2", "MTOR", "MTPN", "MTX1", "MVD", "MVK", "NCAPD3", "NCOA5", "NDUFAF7", "NDUFS1", "NECAP1", "NECAP2", "NPTN", "NRBP1", "NSUN5", "NUCB2", "NUDT12", "OCRL", "OXSR1", "PAFAH1B3", "PCBP2", "PCMT1", "PCYOX1", "PDK3", "PDS5B", "PDXK", "PFDN5", "PFDN6", "PGD", "PHB2", "PIK3C2A", "PKMYT1", "PLEC", "PNP", "POGZ", "POLE", "POLR1A", "PPM1F", "PSMD10", "PSME4", "PUM1", "PYCR1", "QKI", "RABGAP1", "RASA1", "RBP1", "RETSAT", "RPA3", "RPL7", "RPLP0", "RPS19", "RPS25", "RUVBL1", "SAMHD1", "SARS", "SCML2", "SERPINH1", "SGPL1", "SLC25A21", "SLC25A26", "SLC25A32", "SLTM", "SMARCA1", "SMARCA5", "SMARCC2", "SNX1", "SPOUT1", "SRBD1", "SRPRA", "SSB", "STAM", "STK4", "STOML2", "SYMPK", "TARS", "TARS2", "TDRKH", "THOP1", "TIMM13", "TKT", "TMPPE", "TOP2A", "TOP2B", "TOR1AIP1", "TRAP1", "TRMT11", "TSN", "TUBB2A", "TUBB4A", "TUBB4B", "TUBGCP3", "UBA1", "UBA2", "UNC119", "UNC119B", "VAPB", "VCP", "WAPL", "XPO4", "XPOT", "YKT6", "YTHDC2", "ZC3HAV1", "ZDHHC13", "ZNF512B", "ZNF622"]} \ No newline at end of file diff --git a/interpro_ptm/basic/idx2term.json b/interpro_ptm/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_ptm/basic/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_ptm/consensus.joblib b/interpro_ptm/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..56c678ad1cdaab7a068870cc4738adc8f5cb35fa --- /dev/null +++ b/interpro_ptm/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6d28bb1e8c015244d7e8f1ba3b904048a7e0d63facecc042fd1e3f622b95d8fb +size 61411 diff --git a/interpro_ptm/df_merge.tsv b/interpro_ptm/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_ptm/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_ptm/metrics.json b/interpro_ptm/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..de968e4f9bd1d88157a2e6a11407b7e35ff99708 --- /dev/null +++ b/interpro_ptm/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2772, + "annotations_size": 3, + "title": "Average number of proteins per term", + "value": 2.6666666666666665 +} \ No newline at end of file diff --git a/interpro_ptm/paths.json b/interpro_ptm/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..ec2cae2a5cafd093862a7d23b30b161c0e29f7cc --- /dev/null +++ b/interpro_ptm/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_ptm/fragment/C321/C321_val_log2fc"} \ No newline at end of file diff --git a/interpro_ptm/result.tsv b/interpro_ptm/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..911c0f98110fcfc0055bf4e7c9370c039a6363c6 --- /dev/null +++ b/interpro_ptm/result.tsv @@ -0,0 +1 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size diff --git a/interpro_ptm/selections.json b/interpro_ptm/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..1c97bf08bd0f4dbf3f3582f75c178f148004b7a1 --- /dev/null +++ b/interpro_ptm/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["P-type ATPase, phosphorylation site [IPR018303]", "Phosphopantetheine attachment site [IPR006162]", "Translation elongation factor, IF5A, hypusine site [IPR019769]"], "available_proteins": ["ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2C1", "ATP7B", "EIF5A", "FASN"], "leading_proteins": []} \ No newline at end of file diff --git a/interpro_repeat/advanced/idx2term.json b/interpro_repeat/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_repeat/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_repeat/basic/idx2term.json b/interpro_repeat/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..69d1108ba81ae698a484ecb1404590682e360956 --- /dev/null +++ b/interpro_repeat/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Ankyrin repeat [IPR002110]", "1": "HEAT, type 2 [IPR021133]"} \ No newline at end of file diff --git a/interpro_repeat/basic/plot_0.png b/interpro_repeat/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..12127456c45f8a91322a7d16942fac455626a016 --- /dev/null +++ b/interpro_repeat/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:16de361f5d3d72b9d97ee345533c63165b75f7fef87de321ea0909d64317f69a +size 135801 diff --git a/interpro_repeat/basic/plot_1.png b/interpro_repeat/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..3fa43a1b19485ba4760c1b43d38684d941867d50 --- /dev/null +++ b/interpro_repeat/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:896a9decd0b599f352da98df68e478ad42cb1ce903ed79c9db7a6f4b06075353 +size 138056 diff --git a/interpro_repeat/consensus.joblib b/interpro_repeat/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..818e818e1053285f46011d963b0f0ba38f72c086 --- /dev/null +++ b/interpro_repeat/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2af50047777de03cd9eb59e30c843b9f3bd53e278140d85abef7e24bd84d4c79 +size 72265 diff --git a/interpro_repeat/df_merge.tsv b/interpro_repeat/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_repeat/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_repeat/metrics.json b/interpro_repeat/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..899182d1fc2885bf4a6e573efa9077dbd86c2515 --- /dev/null +++ b/interpro_repeat/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2772, + "annotations_size": 71, + "title": "Average number of proteins per term", + "value": 5.366197183098592 +} \ No newline at end of file diff --git a/interpro_repeat/paths.json b/interpro_repeat/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..4b6b8f904be394c5bddae9292b3a15c987fb9de6 --- /dev/null +++ b/interpro_repeat/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_repeat/fragment/C321/C321_val_log2fc"} \ No newline at end of file diff --git a/interpro_repeat/result.tsv b/interpro_repeat/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..3b1271dadef575249d1363e5f1d5edb8dd8fd909 --- /dev/null +++ b/interpro_repeat/result.tsv @@ -0,0 +1,7 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mitochondrial substrate/solute carrier [IPR018108] 0.4913557822267376 1.3308263128185367 0.1832461678021872 0.999999426578674 0.3095448023106362 20 Q9BQT8,Q70HW3,Q9H2D1 3 +Pentatricopeptide repeat [IPR002885] 0.6634163958107618 0.6625061341128282 0.5076469049089147 1.0 0.6553260045187809 3 Q92552,Q96EY7 2 +Ankyrin repeat [IPR002110] 0.3737611013762424 0.5393521524302354 0.589643889567804 1.0 0.7344687045493699 17 O75832,Q8IUH4,Q8IWZ3,Q9BQG2,Q9P2R3,P58546,Q9H6S0,Q96KQ7 8 +HEAT, type 2 [IPR021133] 0.3555579612532054 0.2412565948925372 0.8093562496223476 1.0 0.8913925862988211 10 Q9BU89,Q8TEX9,Q9NXF1,Q86Y56,Q92616,Q14008,Q8TF05 7 +Tetratricopeptide repeat 1 [IPR001440] 0.3533267035079045 0.23451238685287 0.8145872179637539 1.0 0.8913925862988211 10 Q13451,O15294 2 +Hexapeptide repeat [IPR001451] 0.5099313831708246 0.2326108061885139 0.8160636353439912 1.0 0.8913925862988211 3 Q13144,Q96IJ6 2 diff --git a/interpro_repeat/selections.json b/interpro_repeat/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..fdd2b4b322717c3ad93a404eccb7aad481059ab8 --- /dev/null +++ b/interpro_repeat/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Ankyrin repeat [IPR002110]", "Annexin repeat [IPR018502]", "Armadillo [IPR000225]", "Atypical Arm repeat [IPR032413]", "BIR repeat [IPR001370]", "Beta-propeller repeat TECPR [IPR006624]", "Calponin repeat [IPR000557]", "Cation-independent mannose-6-phosphate receptor repeat [IPR000479]", "Chromosome region maintenance repeat [IPR041123]", "Clathrin, heavy chain, propeller repeat [IPR022365]", "Clathrin, heavy chain/VPS, 7-fold repeat [IPR000547]", "Cysteine-rich Golgi apparatus protein 1 repeat [IPR001893]", "Cysteine-rich Golgi apparatus protein 1 repeat, eukaryote [IPR017873]", "Exportin-1, repeat 2 [IPR041235]", "Exportin-1, repeat 3 [IPR040485]", "Filamin/ABP280 repeat [IPR001298]", "Filamin/ABP280 repeat-like [IPR017868]", "Furin-like repeat [IPR006212]", "G-protein beta WD-40 repeat [IPR020472]", "GTF2I-like repeat [IPR004212]", "HAT (Half-A-TPR) repeat [IPR003107]", "HEAT repeat [IPR000357]", "HEAT, type 2 [IPR021133]", "HUWE1/Rev1, ubiquitin binding region [IPR025527]", "Hexapeptide repeat [IPR001451]", "Hs1/Cortactin [IPR003134]", "Importin repeat 4 [IPR041653]", "Importin repeat 6 [IPR041389]", "Importin repeat [IPR040928]", "KI67R [IPR012568]", "Kelch repeat type 1 [IPR006652]", "Kinesin light chain repeat [IPR015792]", "Leucine rich repeat 4 [IPR025875]", "Leucine-rich repeat [IPR001611]", "Leucine-rich repeat, cysteine-containing subtype [IPR006553]", "Leucine-rich repeat, typical subtype [IPR003591]", "Low-density lipoprotein (LDL) receptor class A repeat [IPR002172]", "MORN motif [IPR003409]", "Mbt repeat [IPR004092]", "Microtubule associated protein, tubulin-binding repeat [IPR001084]", "Mitochondrial substrate/solute carrier [IPR018108]", "NHL repeat [IPR001258]", "Nebulin repeat [IPR000900]", "Neuraxin/MAP1B repeat [IPR000102]", "P120R repeat [IPR012586]", "PBS lyase HEAT-like repeat [IPR004155]", "PFTB repeat [IPR001330]", "Paired amphipathic helix [IPR003822]", "Pentatricopeptide repeat [IPR002885]", "Plectin repeat [IPR001101]", "Proteasome/cyclosome repeat [IPR002015]", "Protein of unknown function DM15 [IPR006607]", "Protein prenyltransferase, alpha subunit [IPR002088]", "Proteinase inhibitor I27, calpastatin [IPR001259]", "Pumilio RNA-binding repeat [IPR001313]", "Putative TPR-like repeat [IPR031545]", "Pyrrolo-quinoline quinone repeat [IPR002372]", "RNA helicase p68 repeat [IPR012587]", "RNA polymerase II, heptapeptide repeat, eukaryotic [IPR000684]", "Regulator of chromosome condensation, RCC1 [IPR000408]", "Ribonuclease inhibitor, leucine rich repeat cap [IPR041302]", "Sel1-like repeat [IPR006597]", "Spectrin repeat [IPR002017]", "Spectrin/alpha-actinin [IPR018159]", "Tetratricopeptide repeat 1 [IPR001440]", "Tetratricopeptide repeat 2 [IPR013105]", "Tetratricopeptide repeat [IPR019734]", "Vesicle tethering protein p115, armadillo tether-repeat [IPR041209]", "WD40 repeat [IPR001680]", "Wolframin, Sel1-like repeat [IPR045458]", "Zinc finger, C2H2C-type [IPR002515]"], "available_proteins": ["AAAS", "AAMP", "ACAP2", "ACTN1", "ACTN2", "ACTN4", "AIP", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKRD17", "ANKRD28", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP2B1", "ARMC1", "ARMC6", "ARMCX3", "ARPC1A", "ARPC1B", "ASPH", "BIRC6", "BOP1", "BUB3", "CAST", "CDC23", "CDC27", "CHAF1B", "CKAP5", "CLPB", "CLTC", "CNN2", "CNN3", "COA7", "COPA", "COPB2", "CORO1C", "CRNKL1", "CSTF1", "CSTF3", "CTNNB1", "CTNND1", "CTR9", "CTTN", "DCAF13", "DCAF7", "DDX5", "DNAAF5", "DNAJC3", "DNAJC7", "DOHH", "DSP", "DST", "DTL", "DYNC1I2", "EDC4", "EHMT1", "EHMT2", "EIF2B5", "EIF3I", "ELP2", "EMC1", "EMC2", "EML4", "EPPK1", "FKBP4", "FKBP5", "FKBP8", "FLII", "FLNA", "FLNB", "FLNC", "FNTA", "FNTB", "GCN1", "GEMIN5", "GLG1", "GLS", "GMPPA", "GMPPB", "GRWD1", "GTF2I", "GTF3C2", "GTF3C3", "HCFC1", "HECTD1", "HERC2", "HUWE1", "IFIT5", "IGF1R", "IGF2R", "IPO4", "IPO5", "JUP", "KAT7", "KDELC2", "KLC1", "KLC2", "KLC4", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "LARP1", "LASP1", "LLGL1", "LRBA", "LRCH2", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC59", "LRWD1", "MACF1", "MAP1B", "MAP4", "MAU2", "MKI67", "MRPS27", "MTCH1", "MTCH2", "MTPN", "NAA15", "NASP", "NEK9", "NHLRC2", "NLE1", "NLRX1", "NOP2", "NUDT12", "NUP214", "NUP37", "NUP43", "NXF1", "OGT", "P4HA1", "PAFAH1B1", "PAK1IP1", "PDCD11", "PEX5", "PHIP", "PLEC", "PLRG1", "POLR2A", "PPID", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP4R1", "PPP5C", "PREB", "PRKCSH", "PRPF19", "PRPF39", "PRPF4", "PRPF6", "PSMD1", "PSMD10", "PSMD2", "PTCD3", "PUM1", "PUM3", "PWP1", "PWP2", "RABGGTA", "RACK1", "RAE1", "RAI14", "RANBP2", "RANGAP1", "RAP1GDS1", "RBBP5", "RCC1", "RCC2", "RNH1", "RPAP3", "RRP9", "RSU1", "SART3", "SCML2", "SCRIB", "SEC31A", "SEH1L", "SEL1L", "SETD7", "SGTA", "SHOC2", "SIN3A", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SMU1", "SNRNP40", "SNRPA1", "SPTAN1", "SPTBN1", "SPTBN2", "SRP72", "STIP1", "STRAP", "STRN", "STUB1", "SUGT1", "SYNE2", "TAGLN2", "TBL2", "TBL3", "TEX10", "THOC3", "TMTC3", "TOMM34", "TOMM70", "TTC1", "TTC19", "TTC26", "TTC37", "TTC4", "UNC45A", "USO1", "UTP15", "UTP18", "UTP4", "UTP6", "UTRN", "VPS18", "WDHD1", "WDR1", "WDR18", "WDR3", "WDR33", "WDR36", "WDR41", "WDR43", "WDR46", "WDR5", "WDR6", "WDR61", "WDR70", "WDR73", "WDR75", "WDR77", "WDR82", "WFS1", "WIPI2", "WRAP53", "XAB2", "XPO1", "YTHDC2", "ZDHHC13"], "leading_proteins": ["ANKFY1", "ANKHD1", "CKAP5", "DNAAF5", "DOHH", "EHMT2", "EIF2B5", "FKBP5", "GCN1", "GMPPA", "IPO4", "MRPS27", "MTPN", "NUDT12", "OGT", "PPP4R1", "PSMD10", "PTCD3", "SLC25A21", "SLC25A26", "SLC25A32", "TEX10", "YTHDC2", "ZDHHC13"]} \ No newline at end of file diff --git a/msigdb_gobp/advanced/idx2term.json b/msigdb_gobp/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..67d5df8ffbead4cfb56544381a0e53d0ef033342 --- /dev/null +++ b/msigdb_gobp/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrion organization", "1": "Transmembrane transport", "2": "Ion transport", "3": "Ion transmembrane transport", "4": "Mitochondrial transmembrane transport", "5": "Cellular response to chemical stress", "6": "Mitochondrial membrane organization", "7": "Dna methylation", "8": "Mitochondrial transport", "9": "Protein transmembrane transport"} \ No newline at end of file diff --git a/msigdb_gobp/advanced/plot_0.png b/msigdb_gobp/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..7ec8fbec2239b8a66aa03ae241e6696cf0eed180 --- /dev/null +++ b/msigdb_gobp/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0c9cc0b7b7ad939828c13ec742a1ff77e2f0700d7ba0443042e5f04d3c9e61a5 +size 227563 diff --git a/msigdb_gobp/advanced/plot_1.png b/msigdb_gobp/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..2d188b1e3a36abb12208f311ab853b1a4701b704 --- /dev/null +++ b/msigdb_gobp/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1326abc3205ad24c60dc23f894c4f209421aec61b01f3f7cf39bbea09d9edb16 +size 226582 diff --git a/msigdb_gobp/advanced/plot_2.png b/msigdb_gobp/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..216a271d112e0a44d8a876f2372e8f796a5b3e59 --- /dev/null +++ b/msigdb_gobp/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:08632ca27c40f78cd39e2683d7b3d164fa107388f3212110f1d2735bd2ea4f53 +size 230238 diff --git a/msigdb_gobp/advanced/plot_3.png b/msigdb_gobp/advanced/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..a8469adaad82a7aa4d490a346206821e8fa99dbb --- /dev/null +++ b/msigdb_gobp/advanced/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9b448f0cc5ca05f8855c3b5ea1d4927808a373281c385513070b5fe007bedf44 +size 225670 diff --git a/msigdb_gobp/advanced/plot_4.png b/msigdb_gobp/advanced/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..b467398a62259034401cccfc96b699eed8bc8078 --- /dev/null +++ b/msigdb_gobp/advanced/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2db60dbb38258404691796271929b6295748f22fd2aec8f0936a9a94c5c2f8bd +size 207481 diff --git a/msigdb_gobp/advanced/plot_5.png b/msigdb_gobp/advanced/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..4e4c7457779b5fde48a61f52042835f26d5217f5 --- /dev/null +++ b/msigdb_gobp/advanced/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:347223013f15ddf6eaebed9a495082a8046c09d620d263104fdfe4cbc0c820b8 +size 217514 diff --git a/msigdb_gobp/advanced/plot_6.png b/msigdb_gobp/advanced/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..136447e34a1b085a1e5a68f6d139e94c065c3e0c --- /dev/null +++ b/msigdb_gobp/advanced/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3abb979c524b39b84ccec179a008b4526f491eeb76d358c1981988800640c915 +size 208713 diff --git a/msigdb_gobp/advanced/plot_7.png b/msigdb_gobp/advanced/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..de7c003d10aad80365ad952206eea4020a54c951 --- /dev/null +++ b/msigdb_gobp/advanced/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:397a8deeedbb3d86eb5131490da737153879838d5a3abc23dc320cb073aec4db +size 199564 diff --git a/msigdb_gobp/advanced/plot_8.png b/msigdb_gobp/advanced/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..1f858cbbc18101dad5b2e42be3365f3122fc6eb3 --- /dev/null +++ b/msigdb_gobp/advanced/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c70f5ef9504835e0866b5846f06dd4ad37f1a3416a0d1f65cd0d141306a02b4c +size 211006 diff --git a/msigdb_gobp/advanced/plot_9.png b/msigdb_gobp/advanced/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..51d3e5285d4c4fec35cf4c5913038db292e514b4 --- /dev/null +++ b/msigdb_gobp/advanced/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1550956d2b0eed6170fedd101272cf49bbc4b411038301ad818c1734ab4e5929 +size 200438 diff --git a/msigdb_gobp/basic/idx2term.json b/msigdb_gobp/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..3b4168074230e77a2a612e0ef195e62168eb4f02 --- /dev/null +++ b/msigdb_gobp/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrion organization", "1": "Transmembrane transport", "2": "Ion transport", "3": "Ion transmembrane transport", "4": "Mitochondrial transmembrane transport", "5": "Cellular response to chemical stress", "6": "Mitochondrial membrane organization", "7": "Dna methylation", "8": "Mitochondrial transport", "9": "Protein transmembrane transport", "10": "Embryonic organ development", "11": "Negative regulation of binding", "12": "Protein localization to mitochondrion", "13": "Chemical homeostasis", "14": "Dna methylation or demethylation", "15": "Atp synthesis coupled electron transport", "16": "Negative regulation of transport", "17": "Protein targeting to mitochondrion", "18": "Establishment of protein localization to mitochondrial membrane", "19": "Protein insertion into membrane", "20": "Secretion", "21": "Sulfur compound transport", "22": "Peptidyl lysine acetylation", "23": "Metal ion transport", "24": "Protein acylation", "25": "Regulation of developmental growth", "26": "Respiratory electron transport chain", "27": "Regulation of oxidoreductase activity", "28": "Cation transport", "29": "Dna modification", "30": "Cell surface receptor signaling pathway involved in cell cell signaling", "31": "Negative regulation of transmembrane transport", "32": "Response to bacterium", "33": "Regulation of multicellular organismal development", "34": "Cation transmembrane transport", "35": "Organic acid transport", "36": "Gland development", "37": "Regulation of binding", "38": "Atp metabolic process", "39": "Amide transport", "40": "Inorganic ion transmembrane transport", "41": "Oxidative phosphorylation", "42": "Axon development", "43": "Regulation of protein dephosphorylation", "44": "Protein autophosphorylation", "45": "Glycerolipid biosynthetic process", "46": "Positive regulation of neurogenesis", "47": "Positive regulation of nervous system development", "48": "Regulation of membrane potential", "49": "Aerobic respiration"} \ No newline at end of file diff --git a/msigdb_gobp/basic/plot_0.png b/msigdb_gobp/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..fe1a34cf7fd974537bbd1fcf951b79a895210f04 --- /dev/null +++ b/msigdb_gobp/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b5d328f22f36cdc3dc62db0660046ada2bf87f42d6e1838996be06714d55ff2d +size 140595 diff --git a/msigdb_gobp/basic/plot_1.png b/msigdb_gobp/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..6130833be6a0854488e977b053e4c565e6fbfd84 --- /dev/null +++ b/msigdb_gobp/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8e014de0b3e19cf1377c6fd1cc407f9d0eed4853d79bc1262264046623fd829b +size 146687 diff --git a/msigdb_gobp/basic/plot_10.png b/msigdb_gobp/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..29c9224e66b2e71cd4897a6a23bae9f70f2fb003 --- /dev/null +++ b/msigdb_gobp/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:27ee312c2724f9eb290d21e9807472cf1532a5ea15380c67ef6566ede3d3d2b2 +size 136096 diff --git a/msigdb_gobp/basic/plot_11.png b/msigdb_gobp/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..de38108c4470d158132f55f036024591ed0bae2b --- /dev/null +++ b/msigdb_gobp/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a50fabd1dee8808a63eb40d5375f7a79ef5fd162458dce54e29647097da5cd36 +size 141777 diff --git a/msigdb_gobp/basic/plot_12.png b/msigdb_gobp/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..f1cb91808349d04d43501887fd24846cf1267a68 --- /dev/null +++ b/msigdb_gobp/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:df74923c7b3a1d47f850a6c4c7cfd8f5a44058e9d7d317924a65611afe04ac10 +size 137342 diff --git a/msigdb_gobp/basic/plot_13.png b/msigdb_gobp/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..bcddd77abc712ac01cc8df7985711127059fa082 --- /dev/null +++ b/msigdb_gobp/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:15d3ed8650bc51d77f710543eaec85f34b1dab81982ef8c98ca8a12576ee7c2f +size 139370 diff --git a/msigdb_gobp/basic/plot_14.png b/msigdb_gobp/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..637a2ae2e908ce59f3dd2a0455fca11c629d7aa9 --- /dev/null +++ b/msigdb_gobp/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:50e9a5e7b1cf0b9c0296b50100e3c42bc162842754fed21c635a76d66e9943c8 +size 138192 diff --git a/msigdb_gobp/basic/plot_15.png b/msigdb_gobp/basic/plot_15.png new file mode 100644 index 0000000000000000000000000000000000000000..051ab57ada4ef380166329c00b7934f1ef92117a --- /dev/null +++ b/msigdb_gobp/basic/plot_15.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4c0d84a6f7b634d9dcc8f07b17d9d66c494f2a64b6d9265da842e3866ee60446 +size 142426 diff --git a/msigdb_gobp/basic/plot_16.png b/msigdb_gobp/basic/plot_16.png new file mode 100644 index 0000000000000000000000000000000000000000..21ed0fa0c3059649be8d5fca4db0a95fa6216936 --- /dev/null +++ b/msigdb_gobp/basic/plot_16.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:de94e9b399fe47c5e7522fad39a08f3aac3107a4c95b8acb130ef762207ebb19 +size 139020 diff --git a/msigdb_gobp/basic/plot_17.png b/msigdb_gobp/basic/plot_17.png new file mode 100644 index 0000000000000000000000000000000000000000..90234653543bd886170a52d529e46ca6acf341a4 --- /dev/null +++ b/msigdb_gobp/basic/plot_17.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:266da79d74245c667c998a1f2c53567c54d48f3b51154f9a88e626792b20d197 +size 135743 diff --git a/msigdb_gobp/basic/plot_18.png b/msigdb_gobp/basic/plot_18.png new file mode 100644 index 0000000000000000000000000000000000000000..b8f679d3e64d12b0318fc9b4be5d171ebdc70756 --- /dev/null +++ b/msigdb_gobp/basic/plot_18.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d6613e81b848af226eb52145d6280c938efb078023611e65ca26b5f11b4f3850 +size 139402 diff --git a/msigdb_gobp/basic/plot_19.png b/msigdb_gobp/basic/plot_19.png new file mode 100644 index 0000000000000000000000000000000000000000..166f63f63ecd7fd39317c97c3c9b17d75b874b77 --- /dev/null +++ b/msigdb_gobp/basic/plot_19.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b02d658bff3834ee6884c4ecce2416fd950abc97a45333717a3b5c28d7ca7c6f +size 137732 diff --git a/msigdb_gobp/basic/plot_2.png b/msigdb_gobp/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..64ce8c1fe7dd523031e27206b5be81ae6f7361b9 --- /dev/null +++ b/msigdb_gobp/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2e36680e5fe6f227635622bfda740c2e3129da817009b06675ca64d39f9432f1 +size 139781 diff --git a/msigdb_gobp/basic/plot_20.png b/msigdb_gobp/basic/plot_20.png new file mode 100644 index 0000000000000000000000000000000000000000..50cc8f37ebb1f73672f0aa88f4e46e5ece0b7bc0 --- /dev/null +++ b/msigdb_gobp/basic/plot_20.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:dfef3c8bc551d43de884ea1f294fa5a906da496c44eec0c8c4f47d732ee0b395 +size 134364 diff --git a/msigdb_gobp/basic/plot_21.png b/msigdb_gobp/basic/plot_21.png new file mode 100644 index 0000000000000000000000000000000000000000..39ce10a80bdcf54454f8777d368c5b5cc127e79b --- /dev/null +++ b/msigdb_gobp/basic/plot_21.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:566b96de7fa169dd078501c9018801bea512a45e8f9781a4f0314407ae76797c +size 136701 diff --git a/msigdb_gobp/basic/plot_22.png b/msigdb_gobp/basic/plot_22.png new file mode 100644 index 0000000000000000000000000000000000000000..96eb62f0c2201b8085228869a2c5a1791bd78be5 --- /dev/null +++ b/msigdb_gobp/basic/plot_22.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ee68250c19ba2d1f3abf9cfdba8de35e0511698b1d7c45c2e3bed97ae0d40405 +size 135603 diff --git a/msigdb_gobp/basic/plot_23.png b/msigdb_gobp/basic/plot_23.png new file mode 100644 index 0000000000000000000000000000000000000000..529f54e962f2949102591fff5f5cf0de3730ec34 --- /dev/null +++ b/msigdb_gobp/basic/plot_23.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5fc18f0d27c79683221b326816dce46b5e7fa5d36796b98a5673296d1bfa8bb5 +size 133819 diff --git a/msigdb_gobp/basic/plot_24.png b/msigdb_gobp/basic/plot_24.png new file mode 100644 index 0000000000000000000000000000000000000000..77999c36e4fbae45060a829c23227493081f9bd7 --- /dev/null +++ b/msigdb_gobp/basic/plot_24.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:814ea422cf7b209b67032aa0f2e6f34804b54701d6d02f0e4eb2e3663c63cca5 +size 131137 diff --git a/msigdb_gobp/basic/plot_25.png b/msigdb_gobp/basic/plot_25.png new file mode 100644 index 0000000000000000000000000000000000000000..d2b9b3a89b532611d98b1654aa0216e7cae95d7f --- /dev/null +++ b/msigdb_gobp/basic/plot_25.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:90f9afb73460cb98166d9af3ecde78218953f1e26f0b4fd0c417d8d697e17d40 +size 138436 diff --git a/msigdb_gobp/basic/plot_26.png b/msigdb_gobp/basic/plot_26.png new file mode 100644 index 0000000000000000000000000000000000000000..8be7ab03ec81c538a4c615bb036f464ce1bd6b42 --- /dev/null +++ b/msigdb_gobp/basic/plot_26.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:94c792c9b276b11243e985e83cc3385cc76339d6de3beb5247e37a966883ca12 +size 146907 diff --git a/msigdb_gobp/basic/plot_27.png b/msigdb_gobp/basic/plot_27.png new file mode 100644 index 0000000000000000000000000000000000000000..3db0ec4baa7cdcdaa760a185cd2f70c021b822ca --- /dev/null +++ b/msigdb_gobp/basic/plot_27.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:08b3b4cb678f1d3475c506a0c0b22a0976dfd539db2c268fec945411922a65b9 +size 141497 diff --git a/msigdb_gobp/basic/plot_28.png b/msigdb_gobp/basic/plot_28.png new file mode 100644 index 0000000000000000000000000000000000000000..00383ab6e5f7651445c5dea161fbc3d3c7886eab --- /dev/null +++ b/msigdb_gobp/basic/plot_28.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0e2b36c754ab88b703298df3e1a4762f3d2eb2d53406a85f38eb80cbd3a2511b +size 136043 diff --git a/msigdb_gobp/basic/plot_29.png b/msigdb_gobp/basic/plot_29.png new file mode 100644 index 0000000000000000000000000000000000000000..5eb17b1ae044f98ebd06cc77630ec34ae657d94e --- /dev/null +++ b/msigdb_gobp/basic/plot_29.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bb34bc6906e41cc51732a25dcffcf45804fa52b47860d2d90fc3a8409e9b9d4f +size 132510 diff --git a/msigdb_gobp/basic/plot_3.png b/msigdb_gobp/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..699026693d17675847df055076d36366abf5d9cf --- /dev/null +++ b/msigdb_gobp/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c2a8fa6202e51d7978bf469cf6e92456da3c8154c8633f0cd146ebe58c774a9e +size 145697 diff --git a/msigdb_gobp/basic/plot_30.png b/msigdb_gobp/basic/plot_30.png new file mode 100644 index 0000000000000000000000000000000000000000..85dfd24f55ee92bfbc05bd01543b9affcf1d8941 --- /dev/null +++ b/msigdb_gobp/basic/plot_30.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:99d6bf0b575ace9fc4da88025709dc4ea9d1b6661866ee923dfd103ac7631d80 +size 146548 diff --git a/msigdb_gobp/basic/plot_31.png b/msigdb_gobp/basic/plot_31.png new file mode 100644 index 0000000000000000000000000000000000000000..d59335468deff4e49d2bfb67d40449cb3fca09e7 --- /dev/null +++ b/msigdb_gobp/basic/plot_31.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d14b3f520ec9e0eb854c007f764c17dcf40dea477aa7f4863704a5b6573e7870 +size 141732 diff --git a/msigdb_gobp/basic/plot_32.png b/msigdb_gobp/basic/plot_32.png new file mode 100644 index 0000000000000000000000000000000000000000..0e281d624b24a6572ff634134f57d39da01a9d9a --- /dev/null +++ b/msigdb_gobp/basic/plot_32.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:482234703060f61a59f8c031aa9f1f6b02bc1d05dc3f27208a4c04a0dcc325da +size 131774 diff --git a/msigdb_gobp/basic/plot_33.png b/msigdb_gobp/basic/plot_33.png new file mode 100644 index 0000000000000000000000000000000000000000..259bd4c256a74b4998f3ac21e418a998361b0698 --- /dev/null +++ b/msigdb_gobp/basic/plot_33.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:02e0e676d5fb8329901d772894cb53e7f77c95ecc6a33dc20241c3d1994a0611 +size 144368 diff --git a/msigdb_gobp/basic/plot_34.png b/msigdb_gobp/basic/plot_34.png new file mode 100644 index 0000000000000000000000000000000000000000..91fb48e7f241322368b4cf7b07267f74e8985d12 --- /dev/null +++ b/msigdb_gobp/basic/plot_34.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:609b0b2908a2f543b63833ddf2632fb897aac5351a1ee6588f2f71d914cfb6f8 +size 141671 diff --git a/msigdb_gobp/basic/plot_35.png b/msigdb_gobp/basic/plot_35.png new file mode 100644 index 0000000000000000000000000000000000000000..afe1067e72ee470b18ebcf5ecb4f9d6aacb05dc2 --- /dev/null +++ b/msigdb_gobp/basic/plot_35.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8226e1060e02f45fa4fc3e88ed21cf3bf450603bcdc4033652c49f25a02dc04d +size 136281 diff --git a/msigdb_gobp/basic/plot_36.png b/msigdb_gobp/basic/plot_36.png new file mode 100644 index 0000000000000000000000000000000000000000..7ce494ea42cc971e8453a2bbb28ce184bdc94f08 --- /dev/null +++ b/msigdb_gobp/basic/plot_36.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:808be7a8876d3415ac5d9bad55d240f8770a57ef322efbcadb57a67401089a15 +size 130313 diff --git a/msigdb_gobp/basic/plot_37.png b/msigdb_gobp/basic/plot_37.png new file mode 100644 index 0000000000000000000000000000000000000000..80b42ce4f33ba9b0a8688bba4672fb3b1817cd0a --- /dev/null +++ b/msigdb_gobp/basic/plot_37.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:95cfe1ee43cfffb1755cc2fd6290fa133b6014fadcda25ce919ce2ac29d59884 +size 132016 diff --git a/msigdb_gobp/basic/plot_38.png b/msigdb_gobp/basic/plot_38.png new file mode 100644 index 0000000000000000000000000000000000000000..39f16c5c955a1e07d3f38f02f223c18c371afa80 --- /dev/null +++ b/msigdb_gobp/basic/plot_38.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d8a8f3bdfc677a676c77d44bdd83eac57bc148e801388848c9c34ab0ecb12791 +size 142156 diff --git a/msigdb_gobp/basic/plot_39.png b/msigdb_gobp/basic/plot_39.png new file mode 100644 index 0000000000000000000000000000000000000000..eb0bd72b39f4977c43a0636f8ee55d28b4e088d1 --- /dev/null +++ b/msigdb_gobp/basic/plot_39.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7bba3837187ccdb950567fd483b0f0c3453684fba3b8f0c6248983e30b439619 +size 131036 diff --git a/msigdb_gobp/basic/plot_4.png b/msigdb_gobp/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..7a0c60ae52a4d208a63cc6e82d67cced3cac442a --- /dev/null +++ b/msigdb_gobp/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b9900a032339577868495cfc4549b62ba82ff505453a26942c743a9a45973253 +size 144746 diff --git a/msigdb_gobp/basic/plot_40.png b/msigdb_gobp/basic/plot_40.png new file mode 100644 index 0000000000000000000000000000000000000000..00ff278dd2939b5a3c26ba9c6a2e2cb8f93adaab --- /dev/null +++ b/msigdb_gobp/basic/plot_40.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6d890e86930c769d0f002bfe3d272fed231b231765467ad9a7e1e70f32f5394e +size 146228 diff --git a/msigdb_gobp/basic/plot_41.png b/msigdb_gobp/basic/plot_41.png new file mode 100644 index 0000000000000000000000000000000000000000..be9c1587d5a29c511aae17dd9fb39239b5c4fb91 --- /dev/null +++ b/msigdb_gobp/basic/plot_41.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:462acb382db4994913d87dbe6fe58b3ee69bf2a2349355f7d4c674f862e97a85 +size 146018 diff --git a/msigdb_gobp/basic/plot_42.png b/msigdb_gobp/basic/plot_42.png new file mode 100644 index 0000000000000000000000000000000000000000..dd8e2960738e3fe04939402896fe6a9bdf002746 --- /dev/null +++ b/msigdb_gobp/basic/plot_42.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0f172740cb4bd832d69a097f5fd90ec98081f664870e63ff65f3c5b3019cfeb7 +size 132802 diff --git a/msigdb_gobp/basic/plot_43.png b/msigdb_gobp/basic/plot_43.png new file mode 100644 index 0000000000000000000000000000000000000000..fc4567936270c4470151bc9ced1f2cc3c0e3b6e8 --- /dev/null +++ b/msigdb_gobp/basic/plot_43.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1852c5f79b5d5707dda4280c8de2aeeffcb696b7a3a0ebe181f5e2891131e80a +size 141775 diff --git a/msigdb_gobp/basic/plot_44.png b/msigdb_gobp/basic/plot_44.png new file mode 100644 index 0000000000000000000000000000000000000000..6b2624209a9f4fcf19afbbe70a3d30d700937059 --- /dev/null +++ b/msigdb_gobp/basic/plot_44.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0699f2aa278c5a6d87e79aed635f49cb3de71ce764e8e38e4a370b6d4d20b616 +size 136246 diff --git a/msigdb_gobp/basic/plot_45.png b/msigdb_gobp/basic/plot_45.png new file mode 100644 index 0000000000000000000000000000000000000000..c9b20f8d39c4a2ce761ca82240f00a8e3207605d --- /dev/null +++ b/msigdb_gobp/basic/plot_45.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9821b6071197c19735856f351e87d7ac5657f3c6c110189f92e568ba90180617 +size 137909 diff --git a/msigdb_gobp/basic/plot_46.png b/msigdb_gobp/basic/plot_46.png new file mode 100644 index 0000000000000000000000000000000000000000..b92a4a82afec41a82461dbf773db5f3c6d865244 --- /dev/null +++ b/msigdb_gobp/basic/plot_46.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:710ca0a5d390e29f79a94327cd3873ca9e8381e40a33e68bc59433debee5adb7 +size 136687 diff --git a/msigdb_gobp/basic/plot_47.png b/msigdb_gobp/basic/plot_47.png new file mode 100644 index 0000000000000000000000000000000000000000..0ac7a3b8abb7ea63fce2f58d36851aa2b35898d2 --- /dev/null +++ b/msigdb_gobp/basic/plot_47.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a2a2467ad22a3073e41a4110e4a27504ade372837e24e215da2ca157c7eef241 +size 140950 diff --git a/msigdb_gobp/basic/plot_48.png b/msigdb_gobp/basic/plot_48.png new file mode 100644 index 0000000000000000000000000000000000000000..a2eca9531d65edae9c020db12365a25c29e445e1 --- /dev/null +++ b/msigdb_gobp/basic/plot_48.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f3d43d11c81d60b3433c4edf9d5ed7fef489918ee1e25e3bfc74a4696f0dd002 +size 136843 diff --git a/msigdb_gobp/basic/plot_49.png b/msigdb_gobp/basic/plot_49.png new file mode 100644 index 0000000000000000000000000000000000000000..bb4ef0a17caf44c818a0bdd5049b195432ec0921 --- /dev/null +++ b/msigdb_gobp/basic/plot_49.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:80a0899659e3b6d6bbc0e280372ebca1cb04ff967bcabe26ea7d2846f9f8b54e +size 139170 diff --git a/msigdb_gobp/basic/plot_5.png b/msigdb_gobp/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..8111721d9c87bb8ae9d6b84ee7e1cb8285068049 --- /dev/null +++ b/msigdb_gobp/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d3821affcd741c5aab99f4607762ca7f67896263871c43b2f520f50122443700 +size 145186 diff --git a/msigdb_gobp/basic/plot_6.png b/msigdb_gobp/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..40ae8dab460b8985bfd7437f5ffd7cb9467cd369 --- /dev/null +++ b/msigdb_gobp/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:62734d5c43592eb3e4b78c4db57e84e41ccd2278e5f0f415250c6a6d135ec177 +size 146950 diff --git a/msigdb_gobp/basic/plot_7.png b/msigdb_gobp/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..118bb6ee49cc2e5500311c5d39813800352517d9 --- /dev/null +++ b/msigdb_gobp/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c81e499a9fdf6e990e707a0ca9aa79304119e968f5bbd088d447459ab5110dbd +size 133251 diff --git a/msigdb_gobp/basic/plot_8.png b/msigdb_gobp/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..e9bf00be04ce75a6dc5a207a8d5af375cf60fd38 --- /dev/null +++ b/msigdb_gobp/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:12e860784e351f867be0cc3c192bdc6497b7199323d72291fb908201b2b61006 +size 135307 diff --git a/msigdb_gobp/basic/plot_9.png b/msigdb_gobp/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..58bb2efe5532bf2656f908af0e542e4b29fb7692 --- /dev/null +++ b/msigdb_gobp/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0c3ba8e9c373a4ab9c87b7f4e760ea5a512a6f69bae6b1777dc6d7063bf4f564 +size 137269 diff --git a/msigdb_gobp/consensus.joblib b/msigdb_gobp/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..f30f5f843f33be83348c8370df1d480d29e3ffa7 --- /dev/null +++ b/msigdb_gobp/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:748b3d6e455609371ca53c2f45d917c94238c608f6a4da9f8e920ec02519bcce +size 620307 diff --git a/msigdb_gobp/df_merge.tsv b/msigdb_gobp/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..f7660c2d446c280c0c8639ef287236bb5356cc21 --- /dev/null +++ b/msigdb_gobp/df_merge.tsv @@ -0,0 +1,106 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Mitochondrion organization 35 169 4.607616853567544 4.073103103685583e-06 56.45873786407767 188.26941747572815 1.5905300936136977 0.4100157441778524 20.15716756472138 18.40319032732565 2.034523716094369 0.4327537677377048 0.0426637897208585 0.0039658420121988 4.102086619639013e-05 3.0633860343007014e-08 1.0087093197616757e-07 +Transmembrane transport 34 185 4.528239464005386 5.947715659759822e-06 67.45631067961165 211.1359223300971 1.8122664376950308 0.3598356673827246 27.267027885156203 22.354947126810902 2.251277763144546 0.4188333713481413 1.0 5.847489231884304e-06 5.419882102843301e-06 2.9881720259300906e-06 0.0013866134315822 +Ion transport 31 186 3.6858740276543016 0.0002279190759051 59.95631067961165 203.33495145631068 1.28794420214731 0.4483240343684334 22.7179419701651 20.293344878478432 1.852388371824549 0.4292871393353351 1.0 2.600577767295413e-05 5.72048234089106e-05 3.2483786464106534e-05 0.0043833623800727 +Ion transmembrane transport 23 138 3.3648474449441435 0.0007658599126829 47.09466019417476 154.11893203883494 1.555073205784263 0.3634279635891347 19.61122797656 15.97124025754773 1.9676287128633565 0.411597796705808 1.0 0.00023760371417 0.0002705753263414 0.0001907086055641 0.018439829621363 +Mitochondrial transmembrane transport 11 46 3.099593832602783 0.0019378618485454 19.070388349514563 50.63834951456311 1.9310146760091371 0.188342667216329 9.760351579527285 3.939196260509299 1.9786128158557912 0.3017981993827387 1.0 4.620057885845172e-05 0.0001272982113262 0.0001656967171439 0.0006606900860424 +Cellular response to chemical stress 13 72 3.024746445773798 0.0024884164578524 15.75728155339806 79.70145631067962 0.402779466671678 0.6562176319163813 6.265123092751621 7.907578877532739 0.7656094121344978 0.3407433272819883 1.0 0.1001925468277968 0.0677004014482453 0.0102772468476664 0.1013702811834829 +Mitochondrial membrane organization 9 45 2.9690621532359622 0.0029871017109772 16.983009708737864 46.91019417475728 1.283632855732258 0.3380738792929293 7.413069190635445 4.027718639381892 1.6948461264793506 0.367302285357348 0.0094154570418406 0.0748672511654648 0.0118063250281156 0.001871226289903 0.0019538943066988 +Dna methylation 5 15 2.6038134185561463 0.0092192930765819 4.283980582524272 18.48058252427185 0.3368664558597276 0.5549461558551047 3.1251307824457446 3.053266856273282 0.885226763878063 0.3084732602561963 1.0 0.018891152845815 0.0081402699943151 0.0209774624278664 0.0191096802075466 +Inner mitochondrial membrane organization 4 21 2.5998206796596643 0.009327248588524 9.985436893203884 20.800970873786408 1.138268089020681 0.2873707765098114 4.6289277788641146 2.4012939531921327 1.609232985153232 0.3229583948801056 0.0036288740681575 0.1604648724397155 0.2905786054432941 0.0107533794128866 0.0075038562772923 +Mitochondrial transport 16 78 2.547976655990132 0.0108349721144482 26.76456310679612 83.42233009708738 1.9353944346565397 0.260698067067068 11.29934298946582 6.8259418360610375 1.9296757414965091 0.3685496297416806 1.0 0.008038855889861 0.0046434444090005 0.0021514296290794 0.001144768964443 +Base excision repair 4 18 2.54725757434206 0.0108573261572793 7.453883495145631 19.182038834951456 -0.3247537719984735 0.5062328031987017 3.968359014502092 2.8152441682112026 1.0683653259818937 0.3257311906495272 1.0 0.1916891885455893 0.064474868775922 0.0039301337210019 0.0615644138162473 +Protein transmembrane transport 5 24 2.53501843269529 0.0112441409317345 8.992718446601941 25.191747572815533 1.6893060623430327 0.189108476986505 4.473486660459625 2.7693940759543416 1.4682653164365471 0.2783169275392022 1.0 0.0019447965050573 0.01274759481083 0.0014538287235978 0.0392670739615979 +Embryonic organ development 6 41 2.4728888027687086 0.013402583760959 10.808252427184469 49.04611650485437 -0.1415861818720227 0.6671790479987441 6.169894796538932 6.321124198436358 0.6671970134655505 0.2876453746093586 1.0 0.3575494439628122 0.4459652563012662 0.4365824703085002 0.9429928869296208 +Negative regulation of binding 11 32 2.465004852325952 0.0137011396081958 8.383495145631068 35.71601941747573 -0.0486105873080214 0.7336179078614433 4.192401751281858 4.674287825886914 0.5683693417857227 0.2617004354916468 1.0 1.0 0.6668865806291103 0.0212944171747899 0.0249586021011669 +Protein localization to mitochondrion 13 53 2.4641172736046166 0.0137351163224423 18.37621359223301 58.6747572815534 1.743973973786015 0.2835887708870952 7.329731795051445 5.553888141183353 1.6030721833013164 0.3628376459321563 1.0 0.0141530490628759 0.0004700765396895 0.0002223160295233 0.0005877416685242 +Chemical homeostasis 32 159 2.4225427982275125 0.0154123101939733 43.762135922330096 177.7597087378641 0.7082111793088889 0.511106347874914 13.668464281922288 17.87763227716401 1.3204137511810292 0.4179418895476048 1.0 0.0041486424940367 0.0017437374405504 0.0398662562615167 0.0573614599031671 +Dna methylation or demethylation 5 20 2.419375663702557 0.0155471748061888 5.436893203883495 23.0873786407767 0.1823966461973749 0.6056359808060879 4.05524927205437 3.2727376269841373 0.8218396137348795 0.2995399810457916 1.0 0.0343104139968933 0.0193977782239501 0.0578706368690901 0.0739667173438058 +Atp synthesis coupled electron transport 13 34 2.354146000096266 0.0185653175669819 11.567961165048544 37.61407766990291 0.6403585631460136 0.4181082416574377 5.189865284224125 3.9859091462453993 1.417482213086961 0.3703097362636519 1.0 0.3088995675544995 0.0351428570214521 0.0365158472189244 0.0115667886427303 +Negative regulation of transport 17 69 2.344287599255148 0.019063465161758 15.611650485436892 75.64320388349515 0.3645955382320408 0.672265905834044 6.305311383653456 9.610692741829228 0.7092161069595118 0.3277694528833091 1.0 0.0982907065445243 0.0059136099424842 0.0096475401301663 0.0169932732432059 +Protein targeting to mitochondrion 10 42 2.3412590490011427 0.0192188269102011 14.980582524271844 46.067961165048544 1.7767024064550243 0.249920045184344 6.494927942714517 4.708517660750424 1.5433015545903224 0.3384144763122346 1.0 0.008121261283644 0.0087607315482947 0.0010651202779167 0.0029720215421209 +Establishment of protein localization to mitochondrial membrane 5 16 2.3223584212560677 0.0202136442275102 5.572815533980583 16.524271844660195 1.1986544459127668 0.291784793504827 2.8501471321161915 2.5441524813639957 1.2232399066733852 0.3232066755573589 1.0 0.1197698958477507 0.0254170330798906 0.0003662160044705 0.0014291263215289 +Protein insertion into membrane 9 28 2.315561218312778 0.0205822383966955 9.861650485436892 27.67718446601942 1.4180388387951812 0.2751856944202687 4.426616888970974 3.3195747527036987 1.508549988584809 0.3318307488597651 1.0 0.0238997911322505 0.0114825805852386 2.227523280851283e-05 0.0001207634806612 +Secretion 13 126 2.305900845758225 0.0211161733723102 33.99271844660194 147.42233009708738 0.4048828366720226 0.7039215372882776 10.476160889322964 16.385711464618055 0.7463810424968602 0.3447407367793494 0.0448214986260392 0.0624827418196725 0.0031200898107338 0.1211715946590481 0.0699878644602657 +Sulfur compound transport 6 9 2.2816363223644776 0.0225108204103605 3.504854368932039 9.429611650485436 1.339223354728307 0.2167503093092372 2.046184165461596 2.1092484385198076 1.0728301411615704 0.2604171804663498 1.0 0.1444128696349771 0.0033889280105887 0.0009597043018479 0.0007756835718833 +Peptidyl lysine acetylation 11 38 2.274860924064986 0.0229142740968104 12.08495145631068 47.57281553398058 -0.1514646822369765 0.6468883612092663 6.205233208542673 8.481678646075473 0.7237872764784526 0.2926984860369176 1.0 0.0069409825789079 0.0624547835576556 0.0375729530493996 0.0860430378618219 +Regulation of body fluid levels 4 42 2.272749451148722 0.0230412827797781 10.800970873786408 47.99757281553398 0.1903299033243357 0.6669347896911476 4.903357184497507 5.751951457121856 0.7157857547234734 0.3032814108926969 0.0178501373082338 0.2111338255209101 0.2357636696185375 0.4275806954951834 0.3683444328666235 +Metal ion transport 11 87 2.2581041324765727 0.0239391680687441 24.868932038834952 99.21116504854368 0.6600358663497399 0.5322554902435589 9.162889792248723 11.473971032908404 1.1670714049066973 0.3920241658733104 1.0 0.0011194437582937 0.0148046538237848 0.1198436420922187 0.3945488601620493 +Protein acylation 12 50 2.2530005621125477 0.0242591135252532 14.599514563106796 59.01699029126213 -0.1872100471534024 0.6699347326963336 7.249191435145036 9.143526686243206 0.6752676200843762 0.2880858486641104 1.0 0.0028863645339563 0.0437093395196913 0.0587411311434793 0.1980695277083714 +Regulation of developmental growth 10 43 2.252790657628191 0.0242723515312037 10.49271844660194 50.08495145631068 -0.0644935762095791 0.6792105527672508 5.322369480024168 5.548555899552517 0.6515433311025292 0.2791124117304516 1.0 0.2007921459121294 0.2211508004597043 0.0562360435879535 0.1348356244394593 +Regulation of cell shape 4 29 2.247006123118392 0.0246396357911482 7.339805825242719 30.32281553398058 0.1353431361233448 0.6058324727524332 4.730203300416066 3.278373358632852 0.8844166611811607 0.3227574789293689 1.0 0.0138048787139695 0.07599605945654 0.1078587032333331 0.402070196659107 +Protein transmembrane import into intracellular organelle 1 13 2.2465654172124205 0.0246678144046765 4.951456310679611 13.45631067961165 1.503963012554726 0.1758225015375162 2.735521961789203 1.4944992929031071 1.2360761671845495 0.245991671368161 1.0 0.0086801325315587 0.0309447816912241 0.0327618504712588 0.1700540975708267 +Actin cytoskeleton reorganization 2 19 2.24621297130604 0.0246903697846141 5.621359223300971 24.531553398058257 0.1432722904684933 0.6565639285340286 3.822814763445754 2.7723451421052308 0.7762015795209032 0.3070305552520321 1.0 0.0439058261029628 0.1392032841079847 0.2338287905824086 0.4405045662877335 +Response to epidermal growth factor 1 16 2.2400475495347445 0.0250878360952269 3.703883495145631 15.019417475728156 0.1738395736578659 0.5497727450730416 2.8137465032381423 1.7136266120482144 0.8854282879687941 0.2938089399713599 1.0 0.1801156574188796 0.0570680124884745 0.2599607439730003 0.3237873524130525 +Respiratory electron transport chain 15 47 2.235319273770666 0.0253963956089386 15.4126213592233 50.33495145631068 0.497076868891423 0.4388579749555677 7.129498131980449 4.223655269147207 1.4894225458303931 0.3736358875877055 1.0 0.3656394840654732 0.0587257861193188 0.0758182979456255 0.0158416075795489 +Regulation of oxidoreductase activity 5 15 2.222542168307497 0.0262466875685143 4.745145631067961 16.524271844660195 0.8435277245089666 0.3527293456818395 2.542951562396442 1.641953963820047 1.0033906386071183 0.2899852749738094 1.0 0.0265864003984115 0.0015062975318159 0.0085782973943143 0.0424736017287171 +Peptidyl threonine modification 3 22 2.215980146241273 0.0266928618867943 9.16504854368932 29.99514563106796 -0.0411415273683049 0.6594468776063707 4.713844693428075 4.929599102248445 0.7666598513606704 0.3009105531115351 1.0 0.0708561744170628 0.0543806565884393 0.175839009719974 0.2827526651370738 +Cation transport 16 136 2.20473773831097 0.0274725033198146 40.9247572815534 152.4733009708738 1.0106305648473772 0.4693050539746304 15.98502541638414 15.374508146736815 1.5607432077940149 0.4143686874753333 1.0 0.0020289288670451 0.0058601021720781 0.0780592508081057 0.2025767558074137 +Dna modification 7 28 2.2031337656317302 0.0275853219421235 7.449029126213592 29.95631067961165 0.0525974592283249 0.623813202387164 4.976627316341219 4.039613792529995 0.8319095595259771 0.3052628102732242 1.0 0.0519757249383038 0.0351428570214521 0.0100096118072869 0.0317880280661837 +Positive regulation of chemotaxis 4 14 2.1928002357630705 0.0283217749569062 4.817961165048544 17.016990291262136 -0.0747669348721738 0.5950152021464032 2.720538160362209 2.4538858959203873 0.8730469970494442 0.3017299719942363 1.0 0.0238997911322505 0.001215570747561 0.0067437628278578 0.0943237931213244 +Cell surface receptor signaling pathway involved in cell cell signaling 8 62 2.166129207475304 0.0303013148626483 16.466019417475728 72.99514563106796 -0.0797825030224496 0.7196579767051572 8.234211764234859 10.243395965260822 0.6213312770007485 0.2848232460903572 1.0 0.4664905285776053 0.1915750737560269 0.6700849757185577 0.8058332068461422 +Negative regulation of transmembrane transport 6 21 2.160127700299453 0.0307627851769174 4.915048543689321 20.038834951456312 0.539232326403696 0.5077941070021844 2.6236539308948164 2.892649976298608 0.8428552268580063 0.3052620790205636 1.0 0.2613604367755145 0.0210908392716167 0.0007271313066494 0.0106482941092064 +Embryonic skeletal system morphogenesis 0 5 2.153641827393779 0.0312682714070342 3.470873786407767 6.737864077669903 -0.5788132615641626 0.5231945145625122 1.7506243584116794 1.4156624923352077 0.6860368043459244 0.2884193561941915 1.0 0.2217755071466549 0.3886901060989665 0.7179679971585834 0.9253739942983906 +Embryonic skeletal system development 0 5 2.153641827393779 0.0312682714070342 3.4635922330097086 6.757281553398058 -0.582079694374822 0.5202167452110823 1.756025606536949 1.4191206043390825 0.6887507471484303 0.2870770985758255 1.0 0.2855170484549717 0.4830891503762058 0.8167914211191842 0.9691876639349484 +Positive regulation of oxidoreductase activity 3 8 2.1524378146041254 0.0313628880963188 2.179611650485437 8.660194174757281 0.9323097289205834 0.3351781724420858 1.467039765796201 1.084340415669104 0.8660275673035036 0.2662046996688798 1.0 0.0110614955842043 0.0036922874929881 0.007975933763165 0.0765751187554357 +Roof of mouth development 2 5 2.151072118604119 0.0314705077922958 1.3567961165048543 5.674757281553398 0.2725258763562362 0.5897765398203201 1.35688729568406 1.2775293545619089 0.7083434411384373 0.2620246992044097 1.0 0.236404668572991 0.4110414863531019 0.1502740012713029 0.5152597918735173 +Intracellular protein transmembrane transport 3 21 2.147448754800838 0.0317575727477081 7.233009708737864 21.9004854368932 1.450039081018812 0.2247265328975946 3.8281123729210935 2.4627910122818513 1.3220665029303609 0.2876555154826584 1.0 0.018891152845815 0.064474868775922 0.0209774624278664 0.1654347897904788 +Response to bacterium 5 52 2.143393626494197 0.0320815044444036 11.235436893203884 58.29126213592233 0.1154865730357222 0.623946124032815 4.342207231820677 6.938189053279808 0.7858164052781929 0.3116148730227279 1.0 0.085412898243946 0.0532408536289694 0.2650701437757942 0.256033276098425 +Regulation of multicellular organismal development 27 152 2.140809364835353 0.0322894144577643 35.679611650485434 176.2742718446602 -0.2355802429200441 0.734226959967903 14.301003829409888 19.35087409791312 0.5211602889673093 0.2778826243432628 1.0 0.3949642707481551 0.284125309189548 0.1166026904479186 0.3967744215264979 +Mesonephros development 1 5 2.1376985410105287 0.0325412180071125 2.436893203883495 6.330097087378641 -0.2783727952499739 0.5155242582720587 1.7497289826903004 1.6258730262139651 0.9262090950347124 0.3088739946772112 1.0 0.2471994937249445 0.4272726070381734 0.4144983150185649 0.7872066339706525 +Skeletal system morphogenesis 4 17 2.134203305667473 0.0328261422346614 4.259708737864078 18.354368932038835 0.472602243504248 0.5428135061071451 2.346868997179785 3.0862449832926195 0.7734532956175788 0.3019127996783903 1.0 0.1063034743231946 0.2968421091705006 0.3021458839789255 0.4954642207525186 +Cation transmembrane transport 12 104 2.131827653595701 0.0330210174045664 33.43446601941748 118.4004854368932 1.1701058025505957 0.4085228823574113 14.425169362008605 12.553856783980793 1.6663185381795875 0.4066910074955585 1.0 0.0078121497822375 0.0218420961065939 0.1037376591897065 0.4207386783455188 +Organic acid transport 12 42 2.126493403278671 0.033462197949549 16.199029126213592 46.1626213592233 1.6912598339530378 0.23494744574913 7.685833584742487 5.405881453891157 1.4084922190667013 0.315570201131532 1.0 0.1357968236714454 0.0016311188558121 0.0050244138947251 0.0056686198176846 +Mammary gland development 1 21 2.120399049365944 0.0339724068104909 5.216019417475728 20.41747572815534 0.5512318000747981 0.5167791069166561 2.3942560065426757 2.728043047822029 0.8380822573448591 0.3178008321809467 0.0083366025890121 0.3315322885250054 0.1846346124796731 0.3234980437634548 0.582335327414293 +Gland development 8 64 2.120305556704124 0.0339802853666153 13.315533980582524 70.03155339805825 0.3377251159437185 0.619362793080585 5.179070225840264 7.6825027851127485 0.7642435987942063 0.3217888637120522 0.0268732836400404 0.1379235125017981 0.1086525607108703 0.1977396241797119 0.6608368237669422 +Regulation of axonogenesis 3 19 2.117865713017145 0.0341864421168105 6.298543689320389 24.33009708737864 -0.0369493998932667 0.7042332477256763 3.680926674103965 3.330903692400873 0.6576030741176464 0.2748175369765668 1.0 0.0721850613161859 0.2148532790488207 0.3815786430107333 0.6617142033340885 +Regulation of binding 18 86 2.114441022452946 0.0344776170436031 19.097087378640776 94.24514563106796 0.0648739363324729 0.7754225535509562 7.101571770652198 9.54832373476309 0.5438901381570226 0.2709340744095984 1.0 0.3830895335411679 0.1175267214343212 0.0026432851741273 0.0151652831076043 +Protein import into mitochondrial matrix 2 9 2.108926385484624 0.0349509362903586 3.3276699029126213 9.03883495145631 1.4677455160780188 0.1396272549365287 1.9612536628062327 0.7162785445212654 1.2893924319512868 0.2212161399323651 1.0 0.0021914548918381 0.0081668139908558 0.0047525188099938 0.0319207588840927 +Atp metabolic process 40 97 2.1066216112318283 0.0351503919208109 25.97087378640777 107.69417475728156 0.2650120939459569 0.5409439866831242 10.270805368899644 8.059768543771504 1.2580915670575048 0.3757529915372982 1.0 0.2617236697053235 0.0452200134077484 0.0616278021542515 0.012018921729409 +Regulation of transcription regulatory region dna binding 3 9 2.1059867542501465 0.0352055029464111 2.8106796116504853 10.861650485436892 -0.0967348060407985 0.6322747429225943 1.9139453797767536 1.6407389982455596 0.6789294775754656 0.2544787145781005 1.0 0.1604648724397155 0.2905786054432941 0.0556788400800384 0.0977709982026105 +Phospholipid transport 3 12 2.098311882244188 0.0358776035628594 4.038834951456311 13.844660194174756 0.8595089147672731 0.22382450694892 1.931709490395295 2.5542930986961077 1.4491821424024287 0.2459407475876757 1.0 0.001740287381965 0.0114825805852386 0.0315716041303849 0.2244277954553258 +Amide transport 6 34 2.0980824384980616 0.0358978636110507 9.512135922330096 37.99757281553398 0.8625203235532012 0.4243895840783888 3.9342099663331425 4.541875701235624 0.963016155404646 0.3369249994514658 1.0 0.0038407696470514 0.0016311188558121 0.0429573962417852 0.1184856221980056 +Inorganic ion transmembrane transport 12 100 2.096391015095604 0.0360475187856552 32.300970873786405 111.99514563106796 0.9881513097876132 0.4268253140664947 13.185263141323642 11.586314982845243 1.7161030277526947 0.4113555760685328 1.0 0.0050957351350233 0.0382675097389562 0.0606625685670672 0.2010031360730757 +Oxidative phosphorylation 22 56 2.0938228420418645 0.036275764583463 18.140776699029125 60.61893203883495 0.8137621380364766 0.3661293054253088 7.750013302753429 5.582386553809936 1.7413544544034578 0.3762713520958283 1.0 0.1078075701219661 0.0240746373922284 0.0221885792955309 0.0263700255984278 +Postsynapse organization 4 27 2.093044208892896 0.0363452083131188 8.016990291262136 33.179611650485434 0.0413460806202311 0.6449543837585354 5.041786810509166 4.180603831131811 0.7450723367142665 0.2921119253261858 1.0 0.4009047789919011 0.2626134124997454 0.4693102346499263 0.5908644649307436 +Outer mitochondrial membrane organization 1 5 2.0891293573813403 0.0366960803232241 1.4296116504854368 4.956310679611651 1.1531610290328034 0.2630141305877053 0.9963023114429655 0.2044029443827893 0.89744850896642 0.2676384061848394 1.0 0.0233225886554715 0.0452630688877283 0.0052649331336441 0.0205980357409596 +Axon development 10 62 2.087876297694538 0.0368089947702345 15.014563106796116 75.88349514563107 0.4221802741874887 0.6742105443551618 6.65661081388802 8.797672872875632 0.8036898770047755 0.340363217999487 1.0 0.158963117865429 0.2848588100135314 0.2537083838392532 0.7469196150109534 +Regulation of protein dephosphorylation 6 20 2.0819153800020005 0.0373501996952221 5.62621359223301 26.402912621359224 0.2250629807618321 0.6684417685530873 3.402753344471267 3.35920576346508 0.6746964835267337 0.292612066176009 1.0 0.2648597161900051 0.1206058570960581 0.4548024478336659 0.3753107404416634 +Protein autophosphorylation 5 26 2.0739269082658183 0.0380860995752876 11.730582524271844 35.366504854368934 -0.345767035777637 0.6152861121415772 5.7915016959054055 6.2728529315186305 0.7494478075632884 0.3057449464100975 1.0 0.1803245081488168 0.1925599995189902 0.5422383831301291 0.800368403158526 +Glycerolipid biosynthetic process 9 34 2.07258913932405 0.0382105326492967 13.466019417475728 44.71844660194175 0.9430872689732808 0.3767257192898063 6.88753698417372 8.249645447783736 1.3199493331746477 0.3584243730449019 1.0 0.0531834981275408 0.0859070202802107 0.1352421145255364 0.2455581691109625 +Negative regulation of protein dephosphorylation 1 8 2.0675843351055634 0.0386791263579158 3.29126213592233 10.298543689320388 0.1393656283404488 0.5792153588025012 2.281759957598584 2.0915219096573385 0.8247457864923246 0.292260350405948 1.0 0.1155957163384056 0.0236743481254358 0.1241268473016723 0.1246782510881185 +Protein quality control for misfolded or incompletely synthesized proteins 4 11 2.067260570264628 0.0387096075035158 2.79126213592233 12.0 0.5975496500899943 0.4916109553523294 2.034918800227117 1.0096620601608022 0.8606428606135228 0.3201479866678081 1.0 1.0 0.2215080089822307 0.0003662160044705 0.0081448750398107 +Protein localization to cell junction 3 18 2.052256703610103 0.0401447213556207 4.747572815533981 20.16990291262136 0.002954433479682 0.566142416847237 3.2589486856899166 2.8668285291968125 0.9041185928868544 0.311165203118289 1.0 0.2752604452820565 0.4684236618665396 0.4782136573521979 0.4080848893452373 +Nephron development 1 14 2.0513431255782 0.0402335435101826 4.808252427184466 15.194174757281552 -0.3201211753198024 0.6297932085300719 2.982901085811734 2.2718550327536837 0.66176786640264 0.2760400067047936 1.0 0.2989716991852097 0.5020221455829516 0.5303815006947823 0.8789592336894014 +Tetrapyrrole metabolic process 4 17 2.048519639308377 0.0405091097517495 5.652912621359223 19.283980582524272 1.0342508202848784 0.290677507336007 2.6828141040028877 2.549402305664568 1.2308389507353266 0.2976223887279709 1.0 0.0181053013145446 0.0076479800169414 0.0035604731218749 0.0044272704613347 +Positive regulation of neurogenesis 5 36 2.046249927529064 0.0407317874083703 9.196601941747574 40.13106796116505 0.0193843602689804 0.7079454144827407 6.011129492332407 4.103906004104737 0.6059342088312119 0.2684036034325289 1.0 0.4882804103003091 0.1409725470588587 0.4251348281008904 0.6696733256744227 +Positive regulation of nervous system development 5 36 2.046249927529064 0.0407317874083703 9.114077669902912 40.93446601941748 0.0707478234609245 0.7143448967467 5.857042551516769 4.481144580762786 0.6285439247773889 0.2777025287698339 1.0 0.5191611022715147 0.1695370306684589 0.4926289017025647 0.7492744860877607 +Lysosomal protein catabolic process 1 5 2.045599244577247 0.0407958158576156 2.6941747572815533 6.587378640776699 0.838918419522322 0.2080383809566978 1.5899151374262637 1.8707342212441815 1.5239608036504366 0.2420459791980847 1.0 0.0814971443263516 0.1536793025675435 0.3489208021200722 0.2107602618953967 +Regulation of chemotaxis 4 20 2.04070222309172 0.0412804342676724 6.492718446601942 26.155339805825243 -0.0174824940836626 0.6237203663336152 3.3301280462202696 3.729330821967613 0.837371285025588 0.3037004773473938 1.0 0.058039929090825 0.007148000591981 0.0457696928156966 0.3622914957844292 +Body fluid secretion 0 12 2.040326041992932 0.0413178626902066 3.611650485436894 13.691747572815531 0.5614164790218804 0.4834047231691153 2.085469888187935 1.6735027663843434 0.894552067234308 0.3061879015966331 0.0044134954883629 0.1916891885455893 0.3414395457848725 0.6584469028957474 0.6394495546381769 +Regulation of dna methylation 2 7 2.0396811320047283 0.0413820953716901 1.9927184466019416 8.83252427184466 0.7131887814592797 0.4532119966636778 1.6480189308548123 1.5386952097280358 0.8551167704417201 0.3087271346477002 1.0 0.0028214739728005 0.0104522439456993 0.0595020077672019 0.0444773391561563 +Regulation of membrane potential 11 50 2.0391274261869823 0.0414373116226678 12.04611650485437 57.75970873786408 0.1124751219273164 0.6676030681415518 5.082838961521082 5.41286026291516 0.7215479250938304 0.3068872738743891 1.0 0.1769465030312334 0.0624547835576556 0.0143378483307981 0.0045062276399839 +Aerobic respiration 30 81 2.0311249403510345 0.0422423220587908 23.075242718446603 86.43446601941747 0.4685851027775424 0.4381258038241513 10.546552774557412 6.275478278783705 1.570513830163352 0.3792860784147517 1.0 0.1718998483720895 0.0034452134170102 0.0128122339963933 0.0195424837532169 +Porphyrin containing compound metabolic process 4 16 2.0290309827997177 0.0424551346813388 4.91747572815534 16.531553398058254 1.0269348271542438 0.279733852070357 2.276512713100022 2.089380108414912 1.2578863722796805 0.2914421038569487 1.0 0.0116969452261847 0.0040117205948906 0.0012634530541844 0.0011242999322331 +Regulation of endothelial cell migration 11 26 2.0274101040973287 0.0426204894686879 5.495145631067961 27.978155339805824 0.5955926179251096 0.4502618340992453 2.841693008322481 3.167187428757454 1.0132828172462562 0.3207559953771818 1.0 0.3864505475849718 0.0149697134380264 0.0107309350382066 0.0035423824243909 +Peptide transport 4 26 2.025900445561163 0.0427749875859382 7.932038834951456 30.79368932038835 0.0756191257018148 0.6806406995349469 3.843446410342085 4.164535776479206 0.6601343408906243 0.2762665205679514 1.0 0.0159688820707086 0.0038387330014102 0.12772243308668 0.2932117854251359 +Gastrulation 1 22 2.0256406866134755 0.0428016189478241 9.524271844660197 27.68446601941747 -0.5193601571103694 0.5940054113085841 4.737978472278065 4.305387396877874 0.6887378584484931 0.3015175299121682 1.0 0.4260868249492235 0.2934250762621668 0.7663889329003554 0.9224764017551792 +Positive regulation of monooxygenase activity 2 5 2.023862432839552 0.0429843082216288 1.6844660194174756 5.415048543689321 1.0370130759472405 0.2898065983925483 1.0180179945339054 0.878583782950111 0.884976405150879 0.2417237008540366 1.0 0.0683810764565047 0.0081668139908558 0.0047525188099938 0.0319207588840927 +Regulation of postsynapse organization 2 13 2.022996500975963 0.0430735082686084 5.021844660194175 17.104368932038835 0.1098650911734484 0.6028361872288471 3.808779904932688 1.7098459420200842 0.767243504400172 0.2796155797340601 1.0 0.2436179272361805 0.421912020065408 0.7557216701205556 0.5387259637770934 +Organelle disassembly 13 42 2.0117426699415337 0.0442470701079409 11.983009708737864 49.20388349514563 0.433561938027762 0.6160490735942882 4.954374615918461 6.142102393453674 0.8047024382669711 0.3415228222424311 1.0 0.3864505475849718 0.0694784465718328 0.0344942076530019 0.0097929316489596 +Regulation of bone mineralization 2 5 2.0082075299567577 0.0446212431824082 1.3325242718446602 5.320388349514563 0.7220419592899298 0.4163272640314809 1.2102356494008844 1.2730484187057145 0.8403168865039223 0.2764664272349757 1.0 0.0116969452261847 0.0410947893580433 0.0485138308626968 0.2320442767234318 +Kidney morphogenesis 2 6 2.005398871177934 0.0449204222986341 1.1504854368932038 6.298543689320389 0.5679444269039395 0.4923204881150714 1.3389877198337503 1.4880422453073698 0.7785302422673186 0.2834148378199908 1.0 0.0247821522094747 0.0828996528305521 0.1232486771216519 0.453982924256795 +Regulation of epithelial cell differentiation 4 14 2.004055387857908 0.0450641275670693 6.077669902912621 15.444174757281552 -0.6819616761732761 0.4867055413191141 3.20327296330545 2.3891522745147737 0.8727739258050476 0.3301459773130544 1.0 0.2855170484549717 0.4830891503762058 0.5010040264145029 0.4405045662877335 +Protein acetylation 11 45 2.0018444182779613 0.0453014670481806 13.29611650485437 54.56553398058252 -0.1343987622961359 0.6685537876942509 6.8676591499592385 9.0120241391042 0.696003876005096 0.2957249744179026 1.0 0.0105654677450533 0.0885960465136108 0.0674526501354915 0.1639368172788244 +Neutral lipid biosynthetic process 2 5 2.0008059247580365 0.045413308690708 2.1067961165048543 6.288834951456311 1.1186547336258812 0.1821371148552785 1.2515048910859687 1.3298556757746482 1.2887117600293918 0.213034599641239 1.0 0.0002645755687248 0.0018907861943253 0.0248436194903882 0.1355768860648296 +Regulation of system process 11 52 1.997806219979692 0.0457376727553211 12.432038834951456 59.63106796116505 0.142870153937744 0.6256858745623561 5.047131523930307 6.726256754497268 0.8769607822191469 0.3283787852153951 1.0 0.0784094341468755 0.1335652761713511 0.2364999989258535 0.084255039096278 +Protein import 11 79 1.996751803563052 0.0458521515714236 18.941747572815533 84.88106796116504 0.6008949453203009 0.582747226306641 7.950789473798742 5.928615059974957 0.9194508312715092 0.3730411656244653 1.0 0.0503606981327809 0.0806523989536535 0.0240415792345383 0.0218749655856773 +Protein localization to synapse 2 9 1.99662675096498 0.0458657446270647 2.216019417475728 10.259708737864075 0.4052272000352453 0.5200209112383006 1.792496680370015 1.8481236647516075 0.8799565434808945 0.299731001479056 1.0 0.1801156574188796 0.3228040026875091 0.2599607439730003 0.3237873524130525 +Regulation of neuron projection development 12 59 1.987883699098192 0.0468245539774094 13.592233009708735 69.32038834951456 0.4627708713262993 0.6269884749906404 5.824182751460114 9.346058399998094 0.798447623110489 0.3496779713708587 1.0 0.1357693624302005 0.1061803806394637 0.4596458013621011 0.226354162021213 +Nadh dehydrogenase complex assembly 12 24 1.9857668223249088 0.0470592213206595 9.266990291262136 26.96359223300971 1.1245271541492263 0.3013677937017552 4.122702675359976 4.029157649894909 1.4460543016521823 0.3224564676521605 1.0 1.0 0.0969224622413876 0.0021254821485 0.0003157724410723 +Taxis 8 54 1.984928683175533 0.0471524066240069 15.383495145631068 66.66504854368932 0.0159573551720752 0.6551887547826701 6.206676597495536 8.676742809046639 0.9038937835622892 0.3260534579455081 1.0 0.1314977741365594 0.0371845498592783 0.1812669839662922 0.6305921228816533 +Negative regulation of protein binding 6 20 1.9798831730639324 0.0477166576100573 6.033980582524272 23.699029126213592 -0.1843395969628148 0.7198234927474102 2.9302259231649717 3.5929676498866843 0.5489251430194587 0.2508265562940358 1.0 1.0 0.4584187402232305 0.0696325277147963 0.0936280099534273 +Autophagy of mitochondrion 6 25 1.9792934392832249 0.047782977839776 8.643203883495145 32.55582524271845 0.5912176019297528 0.507260115546458 3.9310041488944902 4.499114265424183 1.01585008111736 0.3556742421157408 1.0 0.3022964060814402 0.0329008624112958 0.0331675784735286 0.0695442608317295 +Cellular response to peptide 7 67 1.9786795350867588 0.0478520985098689 15.512135922330096 71.98543689320388 0.1339793674773638 0.7290046555586139 7.235453991765964 8.363395832893957 0.6604460800519434 0.2979149736137888 1.0 0.0195645390146145 0.052403614812658 0.147973089304468 0.4796573902039235 +Regulation of protein acetylation 3 22 1.9630508399578648 0.0496402669238404 5.281553398058253 23.131067961165048 0.0567232640837762 0.6808748965096674 3.333173873711266 3.923084013865533 0.6389369975328789 0.2655257172247184 1.0 0.0002371307422986 0.0029857674071122 0.0182137534470802 0.0343418129303489 +Phosphatidylcholine metabolic process 4 11 1.9618506908716595 0.0497798700217897 3.75 12.592233009708735 0.9144963280277142 0.2812959412325629 1.879404212556404 2.4412987678409657 1.1545250012369797 0.2602001877022786 1.0 0.0143944751365022 0.0054550629616739 0.0129129153231811 0.0364899571255289 diff --git a/msigdb_gobp/metrics.json b/msigdb_gobp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..9e1b4c0993c809d47e3a36f7fc0a3eccb3b19df8 --- /dev/null +++ b/msigdb_gobp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2772, + "annotations_size": 6314, + "title": "Average number of proteins per term", + "value": 17.38470066518847 +} \ No newline at end of file diff --git a/msigdb_gobp/paths.json b/msigdb_gobp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..73ffe99dc23c3caa6c29bcd0d0d070717529b635 --- /dev/null +++ b/msigdb_gobp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gobp/fragment/C321/C321_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gobp/result.tsv b/msigdb_gobp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..78b75f24402bae635c927beaeaf62de9ad4dd1c0 --- /dev/null +++ b/msigdb_gobp/result.tsv @@ -0,0 +1,1891 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mitochondrion organization 0.5114096785505817 4.607616853567544 4.0731031036855825e-06 0.0253897440345875 0.0033684490276764 169 Q13505,O95202,O75832,O60830,O75223,Q99595,Q7KZI7,P78310,Q9NVI7,Q9Y5L4,Q9Y5P4,Q9NS69,Q86Y39,Q8NE86,Q69YU5,Q96TA2,Q5TC12,Q9NX14,Q9Y584,Q96EY1,O14925,P31749,O75489,Q04837,Q15070,P60520,P53365,Q9UII2,Q9Y4P1,Q7L592,O43676,Q96RL7,O14737,Q9Y3B8,Q5HYI7 35 +Transmembrane transport 0.5061648334130834 4.528239464005386 5.947715659759822e-06 0.0368575821586532 0.0033684490276764 185 O60830,O95747,Q99595,Q8IUH4,P33527,Q6P4A7,Q8WTV0,P00846,P35609,Q14728,Q9NS69,O75844,Q8TAD4,O75915,O75027,Q8N4V1,Q9Y376,Q8NE86,Q9BQT8,Q9Y584,P21281,O14925,Q9UDW1,P31749,Q70HW3,P31751,Q01469,P56385,O15439,Q9C0H2,Q9BVC6,Q8IXU6,Q9UHG3,Q8NE01 34 +Ion transport 0.4532130594178155 3.6858740276543016 0.0002279190759051 0.7628933092490336 0.0052503100744952 186 O95747,Q8IUH4,Q9NZD2,Q9Y5P4,P33527,Q6P4A7,P00846,P35609,P04899,Q14728,O75844,Q8TAD4,O75915,P54105,O75027,Q8N4V1,Q9Y376,Q8NE86,Q9BQT8,P21281,Q9UDW1,P31749,Q70HW3,Q9H0H5,P56385,O15439,Q9C0H2,O15173,Q9BVC6,Q9UHG3,Q8NE01 31 +Ion transmembrane transport 0.4702367179627569 3.3648474449441435 0.0007658599126829 0.9920730913244517 0.0119398505893339 138 O95747,Q8IUH4,P33527,Q6P4A7,P00846,P35609,Q14728,O75844,Q8TAD4,O75915,O75027,Q8N4V1,Q9Y376,Q8NE86,Q9BQT8,P21281,Q9UDW1,Q70HW3,P56385,O15439,Q9C0H2,Q9BVC6,Q9UHG3 23 +Mitochondrial transmembrane transport 0.6114276096862111 3.099593832602783 0.0019378618485454 0.999995203051442 0.0251762545508565 46 O95202,O60830,O14925,O75027,Q99595,Q9H2D1,Q8NE86,Q6P4A7,P00846,P56385,Q9BQT8 11 +Cellular response to chemical stress 0.5311163964269487 3.024746445773798 0.0024884164578524 0.9999998527954664 0.030508468960933 72 O95202,O95747,O75915,P31749,O95793,Q96ST3,Q9Y376,P00374,P09601,Q9NWH9,P04792,P33527,P42574 13 +Mitochondrial membrane organization 0.5972848631791242 2.9690621532359622 0.0029871017109772 0.9999999937381217 0.0355859626473782 45 O95202,Q13505,Q9Y5L4,Q15070,O14737,Q9UII2,Q9Y584,Q9NS69,Q5HYI7 9 +Positive regulation of long term synaptic potentiation 0.984115523465704 2.6384331943855037 0.0083290109351628 1.0 0.0814077013074581 2 O95793 1 +Dna methylation 0.7563081333468795 2.6038134185561463 0.0092192930765819 1.0 0.0869947925253016 15 O75844,Q03164,Q9Y2W6,P46100,P51608 5 +Inner mitochondrial membrane organization 0.6887055056861378 2.5998206796596643 0.009327248588524 1.0 0.0876372731963407 21 Q13505,Q9Y584,Q5HYI7,Q9Y5L4 4 +Leukotriene transport 0.9682310469314076 2.570566572058424 0.0101532310306309 1.0 0.0946935018130039 2 P33527 1 +Tripeptide transmembrane transport 0.9682310469314076 2.570566572058424 0.0101532310306309 1.0 0.0946935018130039 2 P33527 1 +Iron coordination entity transport 0.9635379061371838 2.5504260957032585 0.0107591332576886 1.0 0.0993174961828157 2 O75027 1 +Heme transport 0.9635379061371838 2.5504260957032585 0.0107591332576886 1.0 0.0993174961828157 2 O75027 1 +Mitochondrial transport 0.4699826773752377 2.547976655990132 0.0108349721144482 1.0 0.0995808063036775 78 O60830,O14925,Q9Y276,Q99595,Q9Y5L4,Q15070,P23786,P00846,O14737,O95429,Q9UII2,Q9UBX3,Q9Y584,Q9NS69,O95140,P56385 16 +Base excision repair 0.7156201113696501 2.5472575743420593 0.0108573261572793 1.0 0.0996412170887522 18 P18858,P13051,P35244,Q07864 4 +Protein transmembrane transport 0.6621936767207772 2.53501843269529 0.0112441409317345 1.0 0.1020050371307067 24 O60830,O14925,Q99595,Q9Y584,Q9NS69 5 +Ceramide 1 phosphate transport 0.9483754512635374 2.4850801727322835 0.0129522261011212 1.0 0.1114492570507195 2 Q9Y5P4 1 +Embryonic organ development 0.5427836984145653 2.4728888027687086 0.013402583760959 1.0 0.1143566403603991 41 O95747,Q03164,P31749,Q9Y3C6,O75190,Q07864 6 +Negative regulation of binding 0.5982770652303707 2.465004852325952 0.0137011396081958 1.0 0.1165889427037043 32 Q8TEY7,Q7Z5K2,P31749,Q96ST3,Q9UBB9,P09601,P30533,Q08209,Q7L2J0,Q9UNE7,Q9NVN8 11 +Protein localization to mitochondrion 0.5223997278673398 2.4641172736046166 0.0137351163224423 1.0 0.1167207597037702 53 O60830,O14925,Q9Y276,Q99595,P31749,Q9Y5L4,Q15070,O14737,O95429,Q9UII2,Q9Y584,Q9NS69,O95140 13 +Cobalt ion transport 0.9418772563176888 2.456945781686328 0.0140123832747021 1.0 0.1185981072338728 2 Q8N4V1 1 +Regulation of transcription from rna polymerase ii promoter in response to oxidative stress 0.9389891696750898 2.4444168481566617 0.0145086521490664 1.0 0.1219808650721782 2 P09601 1 +Cellular hypotonic response 0.9386281588447644 2.4428496618504663 0.0145718060451418 1.0 0.1221864320969796 2 O95747 1 +Hypotonic response 0.9386281588447644 2.4428496618504663 0.0145718060451418 1.0 0.1221864320969796 2 O95747 1 +Positive regulation of endothelial cell chemotaxis 0.9364620938628152 2.4334415572989525 0.014956049619291 1.0 0.124090009587653 2 Q9NWH9 1 +Regulation of endothelial cell chemotaxis 0.9364620938628152 2.4334415572989525 0.014956049619291 1.0 0.124090009587653 2 Q9NWH9 1 +Chemical homeostasis 0.374027115224089 2.4225427982275125 0.0154123101939733 1.0 0.1261399625144893 159 O95202,Q16822,P09455,Q9Y5P4,Q08209,O76024,Q8WTV0,P04899,Q9BWH2,Q8TAD4,O75027,O95793,O15254,Q96ST3,Q9Y639,Q8NE86,Q9H4M9,Q15067,P31749,Q9NWH9,Q01469,Q96A33,P40763,P42785,P30519,P09601,Q9NWS0,O14745,P04179,Q9Y3B8,P16949,Q8NE01 32 +Mitochondrial proton transporting atp synthase complex assembly 0.933935018050541 2.422454641030467 0.0154160501736471 1.0 0.1261399625144893 2 Q15070 1 +Positive regulation of i kappab phosphorylation 0.933574007220216 2.420884133547158 0.0154828113634351 1.0 0.1261399625144893 2 P31749 1 +Regulation of rna polymerase ii regulatory region sequence specific dna binding 0.933574007220216 2.420884133547158 0.0154828113634351 1.0 0.1261399625144893 2 O75844 1 +Regulation of i kappab phosphorylation 0.933574007220216 2.420884133547158 0.0154828113634351 1.0 0.1261399625144893 2 P31749 1 +Dna methylation or demethylation 0.6699319534450544 2.419375663702557 0.0155471748061888 1.0 0.1262929201521918 20 O75844,Q03164,Q9Y2W6,P46100,P51608 5 +Negative regulation of fatty acid transport 0.9259927797833928 2.3878488487723786 0.0169473102687207 1.0 0.1346457059236902 2 P31749 1 +Positive regulation of glycogen metabolic process 0.9259927797833928 2.3878488487723786 0.0169473102687207 1.0 0.1346457059236902 2 P31749 1 +Mammary gland epithelial cell differentiation 0.9259927797833928 2.3878488487723786 0.0169473102687207 1.0 0.1346457059236902 2 P31749 1 +Embryonic hemopoiesis 0.9209386281588436 2.365767560313208 0.01799273688738 1.0 0.1380390531068255 2 Q03164 1 +Atp synthesis coupled electron transport 0.5671526774213743 2.354146000096266 0.0185653175669819 1.0 0.1410606680119425 34 P13073,O75306,Q9H3K2,P51970,Q9UDW1,O75489,P15954,P14927,O43676,Q16795,Q16718,O14949,P14635 13 +Negative regulation of transport 0.4720286187192196 2.344287599255148 0.019063465161758 1.0 0.1436357029013608 69 O95747,O75915,O95429,P31749,Q9Y376,P53367,P31751,P30533,P09601,Q08209,Q01469,O14745,P35609,P04899,Q13432,P49593,Q16850 17 +Protein targeting to mitochondrion 0.5259770959778648 2.3412590490011427 0.0192188269102011 1.0 0.1446052598669954 42 O60830,O14925,Q99595,Q9Y5L4,O14737,O95429,Q9UII2,Q9Y584,Q9NS69,O95140 10 +Establishment of protein localization to mitochondrial membrane 0.6947630557925017 2.3223584212560673 0.0202136442275102 1.0 0.1484552935627921 16 Q9Y5L4,Q15070,O14737,Q9Y584,Q9NS69 5 +Protein insertion into membrane 0.6036934928524167 2.315561218312778 0.0205822383966955 1.0 0.1484552935627921 28 Q9Y276,Q8N4V1,Q9Y5L4,Q15070,Q96A33,P46379,O14737,Q9Y584,Q9NS69 9 +Secretion 0.4117203012429515 2.305900845758225 0.0211161733723102 1.0 0.1506525634720526 126 Q13505,Q96KP1,O15439,O43768,Q16822,P09601,Q8NE86,P20339,O43760,P20645,Q16850,P04899,Q96A65 13 +Sulfur compound transport 0.8422926659639836 2.2816363223644776 0.0225108204103605 1.0 0.1584540914950018 9 Q8TB61,Q70HW3,Q9H0H5,P33527,O15439,Q9UBX3 6 +Peptidyl lysine acetylation 0.5216243480383301 2.274860924064986 0.0229142740968104 1.0 0.1603998450623143 38 O75844,Q969T9,O43318,Q03164,O75448,Q96ST3,Q9NWS0,Q9BX68,P46379,P51608,Q9P265 11 +Regulation of body fluid levels 0.5178989285461211 2.272749451148722 0.0230412827797781 1.0 0.1603998450623143 42 Q13505,P04899,Q9Y3B8,Q9NWH9 4 +Metal ion transport 0.4221652138075281 2.2581041324765727 0.0239391680687441 1.0 0.1649053065196397 87 O75844,Q8TAD4,O95747,O75027,P31749,O15173,Q8IUH4,Q8N4V1,Q8NE86,P35609,P04899 11 +Protein acylation 0.5047232375901183 2.2530005621125473 0.0242591135252532 1.0 0.1659617901426127 50 O75844,Q969T9,O43318,Q03164,O75448,Q8IUH4,Q96ST3,Q9NWS0,Q9BX68,P46379,P51608,Q9P265 12 +Regulation of developmental growth 0.5144905936042362 2.252790657628191 0.0242723515312037 1.0 0.1659617901426127 43 O75844,Q6IBS0,P31749,Q96ST3,P58107,P80723,Q9UGN5,O95470,Q9P265,Q13043 10 +Regulation of cell shape 0.5877221094509437 2.2470061231183913 0.0246396357911482 1.0 0.1670900266024155 29 Q7KZI7,Q9UQB8,P26038,O75844 4 +Protein transmembrane import into intracellular organelle 0.723401584303192 2.2465654172124205 0.0246678144046765 1.0 0.1670900266024155 13 O60830 1 +Actin cytoskeleton reorganization 0.6510780899625254 2.24621297130604 0.0246903697846141 1.0 0.1670900266024155 19 Q9UQB8,Q8NE86 2 +Response to epidermal growth factor 0.6794693792333923 2.2400475495347445 0.0250878360952269 1.0 0.168694991592399 16 Q9UQB8 1 +Respiratory electron transport chain 0.5074148065072892 2.235319273770666 0.0253963956089386 1.0 0.1700003438160853 47 P13073,O75306,Q9H3K2,P51970,Q9UDW1,O75489,P15954,P14927,O43676,Q15149,Q16795,P04179,Q16718,O14949,P14635 15 +Nad biosynthesis via nicotinamide riboside salvage pathway 0.890252707581227 2.23072306169085 0.0256994790561089 1.0 0.1700003438160853 2 P43490 1 +Regulation of oxidoreductase activity 0.6832598587936821 2.2225421683074975 0.0262466875685143 1.0 0.1727084989146848 15 P31749,P00374,Q15070,Q8WTV0,P04899 5 +Peptidyl threonine modification 0.6201936571752331 2.215980146241273 0.0266928618867943 1.0 0.1727084989146848 22 Q7KZI7,O95747,P31749 3 +Cellular response to oxidised low density lipoprotein particle stimulus 0.886642599277977 2.214726483830594 0.0267788439083744 1.0 0.1727084989146848 2 P31749 1 +Negative regulation of mononuclear cell migration 0.886642599277977 2.214726483830594 0.0267788439083744 1.0 0.1727084989146848 2 P31749 1 +Negative regulation of lymphocyte migration 0.886642599277977 2.214726483830594 0.0267788439083744 1.0 0.1727084989146848 2 P31749 1 +Positive regulation of endocytic recycling 0.8848375451263528 2.20671972752085 0.0273336461389357 1.0 0.1752128342347631 2 P35609 1 +Positive regulation of cholesterol storage 0.8848375451263522 2.2067197275208468 0.0273336461389359 1.0 0.1752128342347631 2 Q8WTV0 1 +Cation transport 0.3942142591153658 2.20473773831097 0.0274725033198146 1.0 0.1755682044142811 136 O75844,Q8TAD4,P21281,O95747,Q9UDW1,O75027,P31749,O15173,Q8IUH4,Q8N4V1,Q9Y376,Q70HW3,Q8NE86,P00846,P35609,P04899 16 +Dna modification 0.5870415900271171 2.2031337656317302 0.0275853219421235 1.0 0.1761109431168538 28 O75844,Q03164,P13051,Q9Y2W6,Q9UGN5,P46100,P51608 7 +Positive regulation of chemotaxis 0.68435563335768 2.1928002357630705 0.0283217749569062 1.0 0.1779340169929413 14 O95747,P49593,Q9NWH9,Q8NE86 4 +Glycoprotein catabolic process 0.8790613718411537 2.181060397253699 0.0291789495319658 1.0 0.1825925543556318 2 O60502 1 +Positive regulation of metallopeptidase activity 0.8776173285198547 2.174636631161973 0.0296573570181437 1.0 0.1848534572680747 2 Q96HY6 1 +Cell surface receptor signaling pathway involved in cell cell signaling 0.4698039450825765 2.166129207475304 0.0303013148626483 1.0 0.187951426340995 62 Q9UQB8,Q8IZT6,P31749,Q7KZI7,P14923,Q13043,P51608,P20339 8 +Negative regulation of transmembrane transport 0.6150187392875388 2.1601277002994532 0.0307627851769174 1.0 0.1900550152710926 21 O75915,O95747,P31749,Q9Y376,Q01469,P35609 6 +Positive regulation of oxidoreductase activity 0.8378515161270871 2.1524378146041254 0.0313628880963188 1.0 0.1915888040360531 8 P04899,Q8WTV0,P31749 3 +Roof of mouth development 0.919276353383545 2.151072118604119 0.0314705077922958 1.0 0.1915888040360531 5 O95747,O95470 2 +Intracellular protein transmembrane transport 0.6129437142717559 2.147448754800838 0.0317575727477081 1.0 0.1922505410633072 21 O60830,O14925,Q99595 3 +Response to bacterium 0.4892380990229563 2.143393626494197 0.0320815044444036 1.0 0.1929167800590137 52 Q9UQB8,P31749,Q16822,Q9NZ08,Q8WTV0 5 +Regulation of multicellular organismal development 0.3677452136692965 2.140809364835353 0.0322894144577643 1.0 0.1933570149101697 152 Q9UQB8,O95747,Q9H2U1,P07196,Q08209,Q9P265,Q8N5W9,O75844,Q6IBS0,Q9Y639,P04792,Q96T37,Q9UGN5,Q9P0M6,Q96G23,Q8IZT6,P31749,Q9NZ08,Q9H0H5,Q96P11,P14923,P09601,Q13951,P80723,P46379,P51608,Q9Y3B8 27 +Mesonephros development 0.9157361911441354 2.1376985410105287 0.0325412180071125 1.0 0.1942015600159815 5 O95747 1 +Skeletal system morphogenesis 0.6510279691636879 2.134203305667473 0.0328261422346614 1.0 0.1953480321108879 17 Q8N5W9,O75844,O95747,O95470 4 +Cation transmembrane transport 0.4120424211803188 2.1318276535957015 0.0330210174045664 1.0 0.1959735071395847 104 P21281,Q8TAD4,O95747,Q9UDW1,O75027,Q8IUH4,Q8N4V1,Q9Y376,Q70HW3,Q8NE86,P00846,P35609 12 +Organic acid transport 0.5008114774974732 2.126493403278671 0.033462197949549 1.0 0.198199172470406 42 O75915,P31749,Q9H2D1,P31751,P09455,Q01469,Q6P4A7,P33527,O15439,Q9BQT8,P23786,Q9UBX3 12 +Phospholipase c activating g protein coupled receptor signaling pathway 0.8664259927797824 2.1247326268000757 0.0336089293824524 1.0 0.1986460132914205 2 P35609 1 +Mammary gland development 0.608525478030095 2.1203990493659437 0.0339724068104909 1.0 0.1999548199485641 21 Q13505 1 +Gland development 0.4599697635551122 2.120305556704124 0.0339802853666153 1.0 0.1999548199485641 64 Q13505,O75844,P62841,P31749,Q16822,P09601,Q9NWH9,P26038 8 +Regulation of axonogenesis 0.628978054700015 2.117865713017145 0.0341864421168105 1.0 0.2006070590386076 19 Q7KZI7,Q9P265,P07196 3 +Regulation of binding 0.4103556513813138 2.114441022452946 0.0344776170436031 1.0 0.2019403283982472 86 O75844,Q8TEY7,Q7Z5K2,P31749,Q7KZI7,P56545,Q96ST3,Q9UBB9,P09601,Q9NWH9,Q08209,Q9BUN8,P07305,Q96HY6,Q71SY5,Q13043,Q9UNE7,Q9NVN8 18 +Nervous system process involved in regulation of systemic arterial blood pressure 0.863898916967508 2.113434898580973 0.0345635616020771 1.0 0.2020376532271222 2 P51608 1 +Negative regulation of systemic arterial blood pressure 0.8638989169675074 2.1134348985809672 0.0345635616020776 1.0 0.2020376532271222 2 P42785 1 +Protein import into mitochondrial matrix 0.8020580048386712 2.1089263854846236 0.0349509362903586 1.0 0.2029997817297106 9 O60830,Q99595 2 +Thrombin activated receptor signaling pathway 0.8628158844765326 2.1085897692051145 0.0349800067345462 1.0 0.2029997817297106 2 Q9NWH9 1 +Atp metabolic process 0.4111007197543949 2.1066216112318283 0.0351503919208109 1.0 0.203801262247934 97 Q9NTK5,P14927,P00846,Q9BRR6,P14635,O75947,P51970,Q9UKK9,O14949,P21281,P13073,P00568,O76031,Q9UDW1,O75489,P15954,P06733,O95182,P06744,Q16795,P40763,P14618,P56385,Q9UII2,Q16718,P04406,P06576,P56556,Q9UJZ1,P54819,O75306,Q9H3K2,P36542,P19404,O43676,O75251,O15294,P34897,Q9H1K1,P54619 40 +Regulation of transcription regulatory region dna binding 0.8013795367611369 2.1059867542501465 0.0352055029464111 1.0 0.2039335280767337 9 O75844,Q96ST3,Q96HY6 3 +Phospholipid transport 0.7210891737187485 2.098311882244188 0.0358776035628594 1.0 0.2056797739021545 12 Q9Y5P4,P33527,Q8WTV0 3 +Amide transport 0.5334549144857573 2.0980824384980616 0.0358978636110507 1.0 0.2056797739021545 34 O43768,Q16822,Q8NE86,Q9Y5P4,P33527,O15439 6 +Inorganic ion transmembrane transport 0.4100749592337533 2.096391015095604 0.0360475187856552 1.0 0.2061630739244812 100 P21281,Q8TAD4,O95747,Q9UDW1,O75027,Q8IUH4,Q8N4V1,Q9Y376,Q8NE86,P00846,P35609,Q9UHG3 12 +Oxidative phosphorylation 0.4763323110319918 2.0938228420418645 0.036275764583463 1.0 0.2069062128093818 56 P14927,P00846,P14635,O75947,P51970,O14949,P13073,Q9UDW1,O75489,P15954,Q16795,P56385,Q16718,P06576,Q9UJZ1,O75306,Q9H3K2,P36542,P19404,O43676,O75251,P34897 22 +Postsynapse organization 0.5763238251664458 2.0930442088928953 0.0363452083131188 1.0 0.206928444805259 27 Q9H2U1,Q9UQB8,P07196,Q96EY1 4 +Outer mitochondrial membrane organization 0.9029207022250622 2.0891293573813403 0.0366960803232241 1.0 0.2082684415228871 5 Q9NS69 1 +Axon development 0.4620135699651341 2.087876297694538 0.0368089947702345 1.0 0.2086283599454768 62 Q9UQB8,Q6IBS0,Q8TEY7,Q7KZI7,Q96ST3,P00374,P07196,Q9Y639,P42574,Q9P265 10 +Regulation of protein dephosphorylation 0.6127652855781908 2.0819153800020005 0.0373501996952221 1.0 0.210749920353559 20 O75116,O43768,Q8IV63,Q92797,P04899,Q86XL3 6 +Negative regulation of amyloid beta clearance 0.856317689530684 2.0794784105849917 0.0375734001326382 1.0 0.2108198902966394 2 Q16850 1 +Protein autophosphorylation 0.578970465016986 2.0739269082658183 0.0380860995752876 1.0 0.2126221332611548 26 O95747,P31749,Q7KZI7,P36507,Q13043 5 +Glycerolipid biosynthetic process 0.5301413277734978 2.07258913932405 0.0382105326492967 1.0 0.2131283596710774 34 O95674,Q92643,Q01968,Q16822,P35790,Q01469,Q9NX62,Q8WTV0,Q8NCC3 9 +Sterol import 0.8545126353790594 2.071379668339648 0.0383233293966613 1.0 0.2135688453755692 2 Q8WTV0 1 +Negative regulation of protein dephosphorylation 0.8175525611363114 2.0675843351055634 0.0386791263579158 1.0 0.2142477566783018 8 P04899 1 +Protein quality control for misfolded or incompletely synthesized proteins 0.7410856862385105 2.0672605702646276 0.0387096075035158 1.0 0.2142477566783018 11 Q9BUN8,Q9UNE7,Q9NYU2,Q96TA2 4 +Protein localization to cell junction 0.62731487411238 2.052256703610103 0.0401447213556207 1.0 0.219838482774839 18 Q9UQB8,P04792,P15924 3 +Nephron development 0.6576860517194251 2.0513431255782 0.0402335435101826 1.0 0.2201339633650718 14 O95747 1 +Tetrapyrrole metabolic process 0.6357433870513579 2.0485196393083775 0.0405091097517495 1.0 0.2212582344053174 17 Q9UII2,P30519,P33527,O75027 4 +Positive regulation of neurogenesis 0.5112783055394865 2.046249927529064 0.0407317874083703 1.0 0.2216604280180821 36 Q9UQB8,Q8IZT6,Q9H2U1,Q9Y639,P07196 5 +Positive regulation of nervous system development 0.5112783055394865 2.046249927529064 0.0407317874083703 1.0 0.2216604280180821 36 Q9UQB8,Q8IZT6,Q9H2U1,Q9Y639,P07196 5 +Lysosomal protein catabolic process 0.8914889208136771 2.045599244577247 0.0407958158576156 1.0 0.2216604280180821 5 O14773 1 +Regulation of chemotaxis 0.6059160985853559 2.0407022230917193 0.0412804342676724 1.0 0.2227847865294319 20 O95747,P49593,Q9NWH9,Q8NE86 4 +Regulation of dna methylation 0.8394703239472763 2.0396811320047283 0.0413820953716901 1.0 0.2229407424717162 7 O75844,Q03164 2 +Regulation of membrane potential 0.4811683616993558 2.0391274261869823 0.0414373116226678 1.0 0.2229627322939768 50 Q9UQB8,O75844,O75915,P31749,P14923,P51608,P78310,P31751,P35609,Q9UII2,P15924 11 +Sequestering of actin monomers 0.8472924187725621 2.038932127033629 0.0414568019818069 1.0 0.2229627322939768 2 Q6IBS0 1 +Aerobic respiration 0.4172500183572389 2.0311249403510345 0.0422423220587908 1.0 0.2264159774865921 81 P14927,Q13423,Q96I99,P00846,P14635,O75947,P51970,P14735,O14949,P13073,Q9UDW1,O75489,P15954,Q15070,Q16795,Q9NZM5,P56385,Q16718,P06576,Q9UJZ1,P11177,P07954,Q9H3K2,O75306,P36542,P19404,O43676,O75251,P34897,Q9H1K1 30 +Porphyrin containing compound metabolic process 0.6408563724643349 2.0290309827997177 0.0424551346813388 1.0 0.2269785947315611 16 Q9UII2,P30519,P33527,O75027 4 +Regulation of endothelial cell migration 0.5719793240485075 2.0274101040973287 0.0426204894686879 1.0 0.227285279142986 26 P57105,Q13630,P31749,Q16539,P14923,P09601,Q9NWH9,P04792,Q8WTV0,P42785,P51608 11 +Peptide transport 0.5717529167811588 2.025900445561163 0.0427749875859382 1.0 0.2276743235354355 26 O43768,Q16822,P33527,Q8NE86 4 +Gastrulation 0.5895743651941813 2.0256406866134755 0.0428016189478241 1.0 0.2276743235354355 22 O95747 1 +Positive regulation of monooxygenase activity 0.8857991555650276 2.023862432839552 0.0429843082216288 1.0 0.2282614988320977 5 Q8WTV0,P31749 2 +Regulation of postsynapse organization 0.6792613576331678 2.022996500975963 0.0430735082686084 1.0 0.2285429674016754 13 Q9H2U1,Q9UQB8 2 +Organelle disassembly 0.4875464099570772 2.0117426699415337 0.0442470701079409 1.0 0.2333968259494896 42 O95140,Q7KZI7,P19784,Q96E11,Q99986,Q9Y4P1,Q9ULC4,Q9Y3C8,P60520,P53365,Q96HY6,Q9UII2,Q9BWH2 13 +Udp glucose metabolic process 0.8407942238267134 2.009658456832347 0.0444673496703003 1.0 0.2343629764760234 2 Q9NYU2 1 +Regulation of bone mineralization 0.8817089590865613 2.0082075299567577 0.0446212431824082 1.0 0.2346395057566452 5 O75844,O95747 2 +Axon ensheathment in central nervous system 0.8404332129963886 2.0080302003051846 0.0446400825443569 1.0 0.2346395057566452 2 Q92542 1 +Kidney morphogenesis 0.8591462189593825 2.005398871177934 0.0449204222986341 1.0 0.235375557173092 6 O75844,O95747 2 +Regulation of epithelial cell differentiation 0.6488551976354 2.004055387857908 0.0450641275670693 1.0 0.2359327541115056 14 O75116,Q9Y3B8,O95747,Q9P0M6 4 +Protein acetylation 0.4835253663129852 2.0018444182779613 0.0453014670481806 1.0 0.2360864466817267 45 O75844,Q969T9,O43318,Q03164,O75448,Q96ST3,Q9NWS0,Q9BX68,P46379,P51608,Q9P265 11 +Neutral lipid biosynthetic process 0.8797773121843476 2.0008059247580365 0.045413308690708 1.0 0.2360864466817267 5 Q16822,Q8WTV0 2 +Regulation of system process 0.4735336634170797 1.997806219979692 0.0457376727553211 1.0 0.2370998898005728 52 Q9UQB8,O75844,Q6PI78,P14923,P78310,Q08209,Q01469,Q9UGN5,P04899,P51608,P15924 11 +Protein import 0.4192360943198661 1.996751803563052 0.0458521515714236 1.0 0.2373740258813825 79 O60830,O14925,P31749,Q99595,P14923,Q9UI26,Q08209,Q5SRE5,O14737,Q13043,Q9NS69 11 +Protein localization to synapse 0.7762826628335879 1.99662675096498 0.0458657446270647 1.0 0.2373740258813825 9 Q9UQB8,P04792 2 +Regulation of neuron projection development 0.4590604608953978 1.987883699098192 0.0468245539774094 1.0 0.2400096311943815 59 Q9H4M9,Q9UQB8,Q6IBS0,Q14195,Q12756,Q7KZI7,Q9H2U1,P31749,P07196,Q9Y639,Q08209,Q9P265 12 +Nadh dehydrogenase complex assembly 0.5752012664219084 1.9857668223249088 0.0470592213206595 1.0 0.2400096311943815 24 O75306,Q7L592,Q9Y276,P51970,Q8TB37,O75489,O43676,Q86Y39,Q15070,Q16795,Q16718,Q9NX14 12 +Taxis 0.4687253108147417 1.984928683175533 0.0471524066240069 1.0 0.2401615880246223 54 Q8TEY7,O95747,P78310,Q9Y639,Q9NWH9,Q8NE86,P33527,P49593 8 +Negative regulation of protein binding 0.5958572323612957 1.9798831730639324 0.0477166576100573 1.0 0.2419943583533352 20 Q8TEY7,P31749,Q9UBB9,P30533,Q9UNE7,Q9NVN8 6 +Autophagy of mitochondrion 0.5696682313808514 1.9792934392832249 0.047782977839776 1.0 0.2421362135476291 25 Q7KZI7,P60520,P53365,Q9Y4P1,Q9UII2,Q9BWH2 6 +Cellular response to peptide 0.4407473266047881 1.9786795350867588 0.0478520985098689 1.0 0.2422920208430733 67 Q9UQB8,P31749,Q16822,P31751,P33527,P35609,P04899 7 +Regulation of protein acetylation 0.5796252895986393 1.9630508399578648 0.0496402669238404 1.0 0.2471834742564108 22 O75844,Q9P265,Q03164 3 +Phosphatidylcholine metabolic process 0.7187442026311913 1.9618506908716595 0.0497798700217897 1.0 0.2476832933944684 11 Q01469,Q8NCC3,P35790,Q8WTV0 4 +Biomineralization 0.7410141540217325 1.9492580353666389 0.0512646173692619 1.0 0.2516141633945374 10 O75844,O95747,Q9UBB9,P18074,Q9Y4P1,Q8N5W9 6 +Response to misfolded protein 0.7894640194043461 1.9489552216019808 0.0513007724799061 1.0 0.2516141633945374 8 Q9BUN8,Q9UNE7,Q9NYU2 3 +Dendritic spine morphogenesis 0.6647509480946661 1.948390624158888 0.0513682408293936 1.0 0.2516141633945374 13 Q9H2U1,Q9UQB8 2 +Endothelial cell migration 0.5209291545777565 1.947882778559504 0.0514289908752441 1.0 0.2516141633945374 33 P57105,Q13630,P31749,Q16539,P14923,P09601,Q9NWH9,P04792,Q8WTV0,P42785,P51608,Q5JRA6 12 +Negative regulation of biomineralization 0.8270758122743664 1.9476442172085129 0.0514575490677038 1.0 0.2516141633945374 2 Q8N5W9 1 +Connective tissue replacement 0.8270758122743668 1.9476442172085129 0.0514575490677038 1.0 0.2516141633945374 2 Q08209 1 +Positive regulation of tissue remodeling 0.8270758122743668 1.9476442172085129 0.0514575490677038 1.0 0.2516141633945374 2 Q08209 1 +Positive regulation of connective tissue replacement 0.8270758122743668 1.9476442172085129 0.0514575490677038 1.0 0.2516141633945374 2 Q08209 1 +Regulation of connective tissue replacement 0.8270758122743668 1.9476442172085129 0.0514575490677038 1.0 0.2516141633945374 2 Q08209 1 +Regulation of peptidyl lysine acetylation 0.5905083441092753 1.9474028344325016 0.051486458521657 1.0 0.2516141633945374 20 O75844,Q9P265,Q03164 3 +Regulation of chromatin binding 0.843500439206709 1.943658532743254 0.0519366422873626 1.0 0.2532262234767625 6 Q08209,Q71SY5,Q7Z5K2,P56545 4 +Synapse organization 0.4642418158666526 1.9423940179072872 0.0520894189414504 1.0 0.2533841226473947 54 Q9UQB8,Q4V328,P56545,Q9H2U1,O95793,P07196,Q9Y639,P51608,Q96EY1 9 +Regulation of dephosphorylation 0.562651791299152 1.9329737844068229 0.0532394273546692 1.0 0.2579844545797249 25 O75116,O95429,O43768,Q8IV63,Q92797,P04899,Q86XL3 7 +Negative regulation of dephosphorylation 0.7124600164845463 1.932006759998524 0.0533586715156704 1.0 0.2581712686756949 11 O95429,O43768,P04899 3 +Cardiac cell development 0.6611092303768704 1.929583329320348 0.0536584860346969 1.0 0.2594178260513601 13 P35609,O75844,P78310 3 +Regulation of biomineralization 0.8384065823953838 1.9234787234795323 0.0544199560387574 1.0 0.2620958065817809 6 O75844,O95747 2 +Lipid localization 0.4352384515209943 1.9202074918823993 0.0548316956801504 1.0 0.2633615396393292 67 O95674,P31749,P35790,P09455,Q9Y5P4,Q01469,P33527,Q8WTV0,O15439 9 +Positive regulation of protein secretion 0.6209609602098207 1.918570246824216 0.0550387440417656 1.0 0.2633615396393292 16 Q16822 1 +Regulation of platelet activation 0.8191335740072188 1.9116127691878269 0.0559258802798305 1.0 0.2633615396393292 2 Q9BWH2 1 +Anion transport 0.4466446484796806 1.9086111206931744 0.0563122762741015 1.0 0.2633615396393292 61 O75915,P54105,Q9BQT8,Q9C0H2,Q9NZD2,Q9Y5P4,Q9H0H5,P33527,O15439,Q14728,Q9UHG3 11 +Kidney epithelium development 0.756032096627653 1.9075225570062393 0.0564529528735178 1.0 0.2633615396393292 9 O95747 1 +Nephron epithelium development 0.756032096627653 1.9075225570062393 0.0564529528735178 1.0 0.2633615396393292 9 O95747 1 +Blood vessel endothelial cell migration 0.5734903833013458 1.903408096404703 0.0569873153859517 1.0 0.2633615396393292 21 P31749,P14923,P09601,P04792,P42785,Q8WTV0,P51608 7 +Cellular response to insulin stimulus 0.4690441352428744 1.9031632701089471 0.0570192442177599 1.0 0.2633615396393292 48 Q9UQB8,P31749,Q16822,P31751,P04899 5 +Nitrogen compound transport 0.3210262321771087 1.9030312243493233 0.0570364710401318 1.0 0.2633615396393292 481 A6NIH7,O60830,Q9Y276,Q99595,Q9C0E2,Q16822,Q9Y5L4,Q9NZD2,Q9Y5P4,Q08209,P33527,Q6P4A7,Q16850,Q8IWJ2,Q92783,Q9NS69,Q4V328,O75915,O75027,Q13596,Q96PU8,Q9Y6M1,Q9P253,Q9H2D1,Q8NE86,P04792,P20645,O95429,Q13432,Q96A65,Q9Y584,Q5JRA6,Q5SRE5,Q96KP1,Q9H4M9,O00148,O14925,P31749,O43768,Q10567,P31751,Q15070,Q9BUN8,P40763,Q8NC96,P53365,O15439,Q9UII2,P60520,P20339,P49593,Q9Y4P1,O94973,Q13043,Q8WUX9,Q8TB61,O95721,O95140,A0AVF1,O15173,O75436,Q9Y282,P14923,Q99797,Q9NVZ3,Q9UI26,Q96RL7,Q8TAG9,O14745,P46379,O00161,O14737,Q9Y3B8,Q16630,Q5HYI7 75 +Organophosphate ester transport 0.5620769360965467 1.9003614856204036 0.0573856975731492 1.0 0.2633615396393292 24 Q8TB61,Q9NZD2,Q9Y5P4,P33527,Q8WTV0,O15439 6 +Glycerophospholipid catabolic process 0.777843443870427 1.899477505291884 0.0575017215071367 1.0 0.2633615396393292 8 Q8NCC3,Q8WTV0 2 +Regulation of protein secretion 0.5266932739119569 1.897058552920031 0.0578202106379159 1.0 0.2633615396393292 31 Q16850,Q16822,Q8NE86 3 +Base excision repair ap site formation 0.815884476534294 1.896846391232144 0.0578482145151788 1.0 0.2633615396393292 2 P13051 1 +Membrane organization 0.3518381043794157 1.8930993596295476 0.0583446573281962 1.0 0.264436567301346 202 Q13505,Q9UQB8,O95202,Q9Y5L4,Q9NZD2,Q9Y5P4,O43760,P33527,Q5JTV8,Q9NS69,O75844,Q15392,Q8N4V1,Q9Y584,Q96EY1,Q01968,P31749,P31751,Q15070,Q96A33,Q9UII2,Q8WUX9,O94901,P46379,O14737,Q5HYI7 26 +Negative regulation of cell cell adhesion 0.6153132300071921 1.887008098592205 0.0591592363814701 1.0 0.2671813308521568 16 P42574,Q13951,P49593,P31749 4 +Regulation of cyclin dependent protein kinase activity 0.6144225154810061 1.8820222836169649 0.0598329901339718 1.0 0.2692697788352801 16 O75832,P31749,P42574,Q9Y3B8,P14635 5 +Positive regulation of neural precursor cell proliferation 0.8269883411782486 1.8781066861822944 0.0603665718512793 1.0 0.270379117452611 6 P04899 1 +Chemical synaptic transmission postsynaptic 0.746920127315676 1.8671867643300164 0.0618755112777438 1.0 0.2755162046598551 9 Q9UQB8,P51608,P31749 3 +Regulation of postsynaptic membrane potential 0.746920127315676 1.8671867643300164 0.0618755112777438 1.0 0.2755162046598551 9 Q9UQB8,P51608,P31749 3 +Positive regulation of muscle hypertrophy 0.8235099870839788 1.8642477142585523 0.0622869256184654 1.0 0.2767625956052013 6 Q12792,Q08209,Q9UGN5,P58546 4 +Regulation of ossification 0.7449972438286633 1.8586560430262191 0.0630759078498319 1.0 0.2785043931215658 9 O75844,O95747 2 +Anterior posterior pattern specification 0.6211125574978139 1.8541036464117089 0.0637243331428312 1.0 0.2797587154404753 14 O95747,Q9Y2W6 2 +Organic anion transport 0.4687055451510268 1.853863038788747 0.0637587569716255 1.0 0.2797587154404753 43 Q8TB61,O75915,Q9BQT8,Q9H2D1,Q9NZD2,Q9Y5P4,P33527,O15439,Q14728 9 +Cardiac conduction 0.6202775081038142 1.8495583894444616 0.0643772248146743 1.0 0.2818847416642536 14 O75844,P78310,P14923,P15924 4 +Neuromuscular process controlling posture 0.8043321299638972 1.844224683550844 0.0651504025076188 1.0 0.2841303807567695 2 P51608 1 +Modification of postsynaptic structure 0.7917034642360402 1.8438917990799817 0.0651989105087054 1.0 0.2841303807567695 7 Q9UQB8 1 +Cellular respiration 0.3907497737409179 1.8428333840575124 0.0653533409448654 1.0 0.2841303807567695 96 Q12931,P14927,Q13423,Q96I99,P00846,P14635,O75947,P51970,P14735,O14949,P13073,Q9UDW1,O75489,P15954,Q15070,Q16795,Q9NZM5,P56385,Q16718,P06576,Q9UJZ1,P11177,P07954,Q9H3K2,O75306,P36542,P19404,O43676,Q15149,O75251,P04179,P34897,Q9H1K1 33 +Mitochondrial respiratory chain complex assembly 0.4934784567190352 1.8418572025044992 0.0654960401906472 1.0 0.2842213043049806 35 O75306,Q7L592,Q9Y276,P51970,Q9NVA1,Q8TB37,O75489,O43676,Q86Y39,Q69YU5,Q15070,Q16795,Q9Y2R0,Q16718,Q9NX14 15 +Response to oxidative stress 0.3889503557047932 1.84113121618344 0.0656023321255603 1.0 0.2844870364291125 87 O43169,Q15392,O95747,O75915,P31749,O95793,Q96ST3,P30519,P00374,P09601,Q15165,Q9NWH9,P04792,P33527,P42574 15 +Heart process 0.5525841778263861 1.838208373814383 0.0660317063491082 1.0 0.2857602425553596 24 O75844,P14923,P78310,P04899,P15924 5 +Bone mineralization 0.7881998810636299 1.8293915907286 0.0673409664732829 1.0 0.2896364010841083 7 O75844,O95747 2 +Establishment of protein localization 0.3150621644887429 1.8278282443482472 0.0675753328701047 1.0 0.2896364010841083 437 A6NIH7,O60830,Q9Y276,Q8NBU5,Q99595,Q9C0E2,Q53EZ4,Q16822,P53367,Q9Y5L4,Q08209,P08240,Q16850,Q8IWJ2,Q92783,Q9NS69,P52294,P57105,Q969T9,O75915,Q4V328,Q13596,Q8N4V1,Q9P253,Q8NE86,P04792,P20645,O95429,Q13432,Q96A65,Q9Y584,Q5JRA6,Q5SRE5,Q96KP1,Q9P0M6,Q9H4M9,O14925,P31749,O43768,Q10567,P31751,Q15070,Q9BUN8,Q96A33,P40763,Q9NPA0,Q8NC96,P53365,P60520,Q9UII2,O94973,P20339,P49593,Q9Y4P1,Q13043,Q8WUX9,O95721,O95140,O75436,A0AVF1,Q99797,Q9Y282,P14923,Q9NVZ3,Q9NWS0,Q9UI26,Q96RL7,Q8TAG9,P46379,O00161,O14737,O43592,Q9Y3B8,Q5HYI7 74 +Intermediate filament organization 0.7871151659204578 1.8248986071566635 0.0680163314565427 1.0 0.2901723762274397 7 P15924,P58107,P07196,O75190 4 +Histone h3 k4 trimethylation 0.7601889498401555 1.8238796666381776 0.0681702663195955 1.0 0.2904366137259961 8 P10412,Q03164,P16403 3 +Establishment of protein localization to organelle 0.3409867007631468 1.82124488340204 0.0685696405467639 1.0 0.291744414024439 163 O60830,Q9Y276,Q99595,Q9Y5L4,Q08209,Q8IWJ2,Q92783,Q9NS69,P20645,O95429,Q9Y584,Q5SRE5,Q9P0M6,O14925,P31749,Q15070,P40763,Q9UII2,Q13043,O95140,Q99797,P14923,Q9UI26,Q96RL7,P46379,O14737 26 +Modification of synaptic structure 0.7364920711205853 1.820846719831234 0.0686301601697692 1.0 0.2918052736107223 9 Q9UQB8 1 +Regulation of nervous system development 0.4514028347125247 1.819949745908994 0.0687666582637811 1.0 0.2918953103867699 54 Q9UQB8,Q6IBS0,Q96P11,Q8IZT6,P31749,Q9H2U1,P07196,Q9Y639,Q08209,Q9P265 10 +Protein localization to cilium 0.6889847538760322 1.8197963379263935 0.068790025634386 1.0 0.2918953103867699 11 Q9H4M9,A0AVF1,Q10713,Q96A65,Q9NQ48 5 +Regulation of dendritic spine morphogenesis 0.7107412631563685 1.810102637412768 0.0702798720692041 1.0 0.2978168538556745 10 Q9H2U1,Q9UQB8 2 +Lipid homeostasis 0.5385525777646255 1.8024365223556456 0.07147675337967 1.0 0.300437983008766 26 Q9H4M9,O15254,P09455,Q9Y5P4,Q8WTV0,Q9BWH2 6 +Cellular response to osmotic stress 0.7088349468407392 1.801282672906761 0.071658337450299 1.0 0.300437983008766 10 Q9Y376,O95747,P42574 3 +Epithelial cell differentiation involved in kidney development 0.827564934451589 1.7987761789686023 0.0720540929061939 1.0 0.300693683152484 5 O95747 1 +Cell differentiation involved in kidney development 0.827564934451589 1.7987761789686023 0.0720540929061939 1.0 0.300693683152484 5 O95747 1 +Phosphatidylcholine catabolic process 0.9776724059457635 1.7978658569330548 0.0721982679156103 1.0 0.3008475026402351 3 Q8WTV0 1 +Cellular response to cadmium ion 0.806776828790089 1.7973407364987608 0.0722815428421344 1.0 0.3008475026402351 6 P09601,P31749 2 +Negative regulation of secretion 0.6098435415014104 1.7926157009190735 0.073034394104452 1.0 0.3017926468426112 14 Q16850,P04899,P09601 3 +Tetrapyrrole catabolic process 0.8230599056860012 1.7811749842075868 0.0748838689994055 1.0 0.3054196551322673 5 P30519,P33527 2 +Mesoderm development 0.6569800104453494 1.7811324477540595 0.0748908160403525 1.0 0.3054196551322673 12 O95747 1 +Regulation of cellular component size 0.4108813475354207 1.7795545798779102 0.0751488850757153 1.0 0.3059252484642597 74 Q9UQB8,Q6IBS0,P20936,P54105,Q96ST3,P07196,P26038,P58546,P35609,Q9P265,P20339 11 +Cartilage development 0.6072084737553941 1.7781920238859723 0.0753723224842213 1.0 0.3060455589487932 14 O75844,Q96HY6,O95747,Q8N5W9 4 +Regulation of epithelial cell migration 0.4705881645000319 1.7759001388882367 0.0757493780753006 1.0 0.3068778966780205 37 P31749,P14923,P09601,Q9NWH9,P04792,P58107,P42785,Q8WTV0,P49593 9 +Regionalization 0.5871092748961556 1.7712280732909118 0.0765227826888648 1.0 0.3091265834276983 17 O95747,Q9Y2W6 2 +Process utilizing autophagic mechanism 0.3668803559143091 1.7696581740475676 0.0767841014997487 1.0 0.3093101660047987 135 Q8TEY7,Q7KZI7,Q92783,Q9BWH2,O75844,Q9P253,P04792,Q96HY6,Q96A65,P21281,O43318,P31749,Q9NWH9,P40763,P60520,P53365,Q9UII2,O95721,P20339,Q9Y4P1,O95140,Q8WUX9,P09601,Q96RL7,P42574,Q9UNE7 26 +Urogenital system development 0.4696280008733924 1.7678139859367372 0.0770920060089788 1.0 0.3096430826594734 37 O75844,O95747,Q10567,P80723,O95470 5 +Iron ion transport 0.7238637996346862 1.7644831787526531 0.0776506649540356 1.0 0.311490659796557 9 Q8N4V1,O75027 2 +Histone h3 k4 methylation 0.5602261244104386 1.7617818315387357 0.0781061655699215 1.0 0.3131189393069744 20 P10412,Q03164,Q9NWS0,P16403 4 +Positive regulation of neuron projection development 0.5272315686094625 1.7574436175717014 0.078842224243445 1.0 0.3152106687491644 27 Q9UQB8,Q6IBS0,Q14195,Q7KZI7,Q9H2U1,Q9Y639 6 +Digestion 0.7221414697599738 1.7567756663155978 0.0789560543154865 1.0 0.3152106687491644 9 Q8WTV0 1 +Intrinsic apoptotic signaling pathway in response to osmotic stress 0.7848375451263516 1.7550305550082137 0.0792540814875439 1.0 0.3152106687491644 2 P42574 1 +Cellular response to peptide hormone stimulus 0.4352326526244777 1.75093515956188 0.0799570795999631 1.0 0.3173986238696062 59 Q9UQB8,P31749,Q16822,P31751,P35609,P04899 6 +Synaptic vesicle membrane organization 0.8147247449576287 1.7485429997067288 0.0803700465879053 1.0 0.3185758665676287 5 O43760,O95721 2 +Regulation of transporter activity 0.4595406557390348 1.7485110665192607 0.0803755710234768 1.0 0.3185758665676287 38 P35609,O95747,Q03164 3 +Embryo development 0.3361374135512733 1.7455758814514857 0.0808846762462842 1.0 0.3197907613143637 161 O95747,Q03164,Q9NY61,Q9H9Y6,Q9H2U1,Q9Y5P4,P14635,Q9Y3C6,Q96ST3,Q96A65,Q01968,P31749,Q9Y2W6,O75190,Q9H0H5,Q13043,Q07864,P80723,P46379,P42574 20 +Long term memory 0.7819494584837524 1.7417775113298526 0.081547383272551 1.0 0.3216053578906229 2 P51608 1 +Export from cell 0.3802525724373137 1.7402854141838175 0.0818089139130056 1.0 0.3224330406686171 113 Q16822,O43760,Q08209,P33527,Q16850,P04899,Q92783,Q9P253,Q8NE86,P20645,Q5JRA6,Q96A65,Q96KP1,O43768,O15439,P40222,O95721,P20339,P56545,P09601,Q8TAG9,O00161 22 +Anion transmembrane transport 0.4661890488376141 1.738819710861946 0.082066480366661 1.0 0.3226178183023275 37 Q8TB61,O75915,Q9BQT8,Q9H2D1,P33527,O15439,Q14728,Q9UHG3 8 +Positive regulation of endothelial cell migration 0.5563584763009752 1.7378733480304709 0.0822331328044576 1.0 0.3226178183023275 20 Q9NWH9,P09601,Q8WTV0,P31749 4 +Mesenchyme morphogenesis 0.9601347950612288 1.7341042526814594 0.0828995871063527 1.0 0.324304828370205 3 O95747 1 +Response to insulin 0.4407973669173496 1.7337939014459198 0.0829546581265436 1.0 0.3243193259510816 55 Q9UQB8,P31749,Q16822,P31751,P04899 5 +Fatty acid transport 0.5879968933463623 1.7331425952173616 0.083070327110766 1.0 0.3245705726345152 16 P09455,Q01469,P31751,P31749 4 +Regulation of lymphocyte migration 0.7640325060075616 1.728886921549379 0.083829335218398 1.0 0.3267274213388675 7 P26038,O95747,P31749 3 +Mitochondrial electron transport nadh to ubiquinone 0.5548455958769105 1.728509627542265 0.0838968964647723 1.0 0.3267890217634626 20 O75306,P51970,O75489,P19404,O43676,O95182,Q16795,O75251,Q16718,P56556,Q9H1K1 11 +Regulation of embryonic development 0.5863135549597054 1.723598569790059 0.0847803369141084 1.0 0.3290123216199637 16 Q9H0H5,O95747,P46379 3 +Base excision repair gap filling 0.736809983476127 1.72301386885214 0.0848860170569572 1.0 0.329220093180361 8 P18858 1 +Excretion 0.8064444005595113 1.716042575441404 0.0861542502333447 1.0 0.3326028694391703 5 P04899,P09601 2 +Respiratory burst involved in inflammatory response 0.7754512635379041 1.7119240412828614 0.0869106675412569 1.0 0.3341985108742367 2 P39019 1 +Respiratory burst involved in defense response 0.7754512635379041 1.7119240412828614 0.0869106675412569 1.0 0.3341985108742367 2 P39019 1 +Chondroitin sulfate proteoglycan metabolic process 0.7740072202166044 1.705283732561616 0.0881415200292332 1.0 0.33626921901183 2 Q9NX62 1 +Regulation of lipid catabolic process 0.7582677463587693 1.7047935173399735 0.0882329409946129 1.0 0.336414727922697 7 Q8WTV0,P31749 2 +Positive regulation of cell cycle g2 m phase transition 0.6643488903833351 1.7008789773454196 0.088965714986231 1.0 0.3377808324853054 11 Q96ST3,P14635 2 +Inorganic anion transport 0.5495557542314065 1.6957189337572771 0.089939121094219 1.0 0.3408113278254625 20 Q9C0H2,P54105,P33527,O15439,Q9UHG3 5 +Glomerulus development 0.9309260634170315 1.6870267323551515 0.0915982118387137 1.0 0.3434497348254637 4 O95747 1 +Positive regulation of amyloid precursor protein biosynthetic process 0.7700361010830303 1.6870117050413225 0.0916011012743238 1.0 0.3434497348254637 2 Q92542 1 +Transition metal ion transport 0.5898097019765028 1.6825419104062125 0.0924638051301089 1.0 0.3463527603124679 14 O15173,Q8N4V1,O75027 3 +Pattern specification process 0.5282386760923993 1.677461082579723 0.0934523535046354 1.0 0.3485281512275653 24 O95747,P80723,Q9Y2W6 3 +Metanephros development 0.7506282348722221 1.6727977318793497 0.094367121541512 1.0 0.3506012520746194 7 O95747 1 +Activation of protein kinase activity 0.5826483712527227 1.671753014845589 0.0945730353371678 1.0 0.3506012520746194 15 Q7KZI7,Q9Y376,O43318 3 +Response to food 0.7501457357167626 1.6707744287163944 0.0947662412081948 1.0 0.3506012520746194 7 P80303 1 +Regulation of anatomical structure morphogenesis 0.3673644833666189 1.670676417548421 0.0947856093271104 1.0 0.3506012520746194 127 Q9UQB8,O75844,P20936,O95747,Q6IBS0,Q7KZI7,P14923,Q9H2U1,Q9NZ08,P09601,P07196,Q8NE86,P04792,P26038,Q08209,P51608,Q9P265 17 +Segmentation 0.6578712401398382 1.6694292959670534 0.0950323317550341 1.0 0.3513080460780359 11 O95747,Q9Y2W6 2 +Neural tube patterning 0.7649819494584814 1.6637335714516417 0.0961656842167553 1.0 0.3536702004795953 2 P17612 1 +Dorsal ventral neural tube patterning 0.7649819494584814 1.6637335714516417 0.0961656842167553 1.0 0.3536702004795953 2 P17612 1 +Regulation of dendritic spine development 0.6556322663862458 1.658542290595619 0.0972080589106856 1.0 0.3559435978155288 11 Q9H2U1,Q9UQB8 2 +Positive regulation of epithelial cell proliferation 0.5519865653445951 1.6583854247835397 0.0972396965713855 1.0 0.3559435978155288 19 O95747,P31749 2 +Response to peptide 0.3752647505615452 1.6583608792824724 0.0972446478035773 1.0 0.3559435978155288 89 Q9UQB8,P31749,Q16822,P07196,P31751,P33527,P35609,P04899 8 +Dendritic spine development 0.5518372497352371 1.6574777022558804 0.0974229333004594 1.0 0.3561787002188768 19 Q9H2U1,Q9UQB8 2 +Fibroblast migration 0.5852215965825169 1.657204628119315 0.0974781111780518 1.0 0.3561787002188768 14 O95429,O95470,P31749 3 +Exocytosis 0.4197322739471229 1.6562765401549504 0.0976658291234611 1.0 0.3565690607346506 62 Q96KP1,O15439,O43633,P56545,P40222,Q9P253,P09601,P20339,Q7Z392,O43760,Q5JRA6,Q8TAG9,O00161,P04899,O95721,Q92783,Q96A65,O15498 18 +Protein localization to organelle 0.322778161237109 1.6561181738272632 0.0976978896216258 1.0 0.3565690607346506 292 O60830,Q9Y276,Q99595,Q9Y5L4,Q08209,Q5JTV8,Q8IWJ2,Q92783,Q9NS69,O14773,Q96ST3,Q8N4V1,P26038,Q7L2J0,P20645,Q76FK4,Q96HY6,O95429,Q96A65,Q9Y584,Q5SRE5,Q5JRA6,Q9P0M6,Q9H4M9,O14925,P31749,P50748,O75190,Q15070,Q9NZM5,Q96A33,P40763,P60520,Q9NPA0,Q9UII2,Q13043,O95140,Q9NVN8,Q8WUX9,O94901,Q7Z5K2,A0AVF1,Q99797,Q14789,P14923,Q9UI26,Q96RL7,P46379,P46100,O14737 50 +Cardiocyte differentiation 0.5414214731696083 1.645149671949223 0.0999389492855962 1.0 0.3616129087617504 20 P35609,O75844,P78310,Q9UGN5 4 +Iron ion transmembrane transport 0.9353599668114244 1.6436336044842057 0.100251908209324 1.0 0.3622541754076106 3 O75027 1 +Regulation of long term neuronal synaptic plasticity 0.9181663338248074 1.6405710398964617 0.1008864906675979 1.0 0.3639713948119084 4 Q9Y639 1 +I kappab phosphorylation 0.7676177239650619 1.6393372518685083 0.1011430418965162 1.0 0.3642995815941834 6 Q96HY6,P31749 2 +Negative regulation of stem cell differentiation 0.7853235481102518 1.632789488199325 0.1025132786449605 1.0 0.3677385488954266 5 Q00839,P40763,Q14004 3 +Negative regulation of leukocyte cell cell adhesion 0.6043942578198727 1.632701037156752 0.102531889207708 1.0 0.3677385488954266 13 P42574,Q13951,P31749 3 +Cell cell adhesion 0.3747376657454321 1.63240107109859 0.1025950236533432 1.0 0.3677385488954266 85 Q9UQB8,P15924,P31749,P14923,P78310,Q9Y639,Q13951,O75190,P04792,P26038,P42574,Q5JRA6,P49593,Q96EY1 14 +Muscle adaptation 0.6273240917945903 1.6314437123170824 0.102796727716254 1.0 0.3677385488954266 12 Q12792,P09601,Q08209,Q9UGN5,P58546 5 +Endothelial cell chemotaxis 0.9305396313594072 1.625983032439171 0.1039532649274366 1.0 0.368742086939233 3 Q9NWH9 1 +Cell chemotaxis 0.4842637318239948 1.6215939954912677 0.1048903091714783 1.0 0.3712299140750276 32 O95747,P78310,Q9NWH9,Q8NE86,P33527 5 +Positive regulation of response to external stimulus 0.4322361425208159 1.62151526440308 0.1049071790051601 1.0 0.3712299140750276 53 O95747,Q96ST3,Q9NWH9,Q8NE86,P04792,P33527,P49593 7 +T cell homeostasis 0.7631814154022089 1.621322043412177 0.1049485898992594 1.0 0.3712299140750276 6 Q96EY1,P31749 2 +Positive regulation of protein polymerization 0.5156822859276317 1.6185671757245308 0.1055404223580935 1.0 0.372280573613968 25 Q9UQB8,P51608,Q9NWH9 3 +Negative regulation of cell death 0.3358647368967395 1.61712213387084 0.1058519199754215 1.0 0.3731708669596938 191 O95747,Q9NY61,P07196,Q9NVI7,P04899,Q15392,Q96ST3,P04792,Q13217,Q9UGN5,Q96TA2,Q96HY6,Q96EY1,P20936,P31749,O75489,Q9NWH9,P31751,O75190,Q8WUX9,Q04760,P13051,P09601,Q9Y3E5,Q9BVC6,P46379,P42574,P51608,Q9Y3B8 29 +Pentose phosphate shunt non oxidative branch 0.7545126353790589 1.6154394703223716 0.1062155584907285 1.0 0.3739840689802364 2 P37837 1 +Proton transporting two sector atpase complex assembly 0.9276411490917712 1.6153628611559412 0.1062321379563751 1.0 0.3739840689802364 3 Q15070 1 +Cell migration 0.3337326157152587 1.6133981041957008 0.1066580447664231 1.0 0.3749659769795077 180 Q8TEY7,O95747,Q7KZI7,P78310,Q02952,Q08209,P33527,Q8WTV0,P04899,P57105,Q9NQW6,Q8NE86,P04792,P26038,Q96HY6,O95429,Q5JRA6,Q96JJ3,Q96G23,Q8IZT6,P31749,P39019,Q7Z7K6,Q9NWH9,P31751,P40763,P42785,Q13043,P49593,Q14195,O00139,P14923,P09601,P04179,O14745,P58107,O95470,O94901,P51608 39 +Regulation of transmembrane transport 0.4134074605623117 1.61299964056408 0.106744585878739 1.0 0.3750613885577953 63 O75844,Q8TAD4,O75915,O95747,P31749,Q9Y376,Q01469,Q9BVC6,P35609 9 +Negative regulation of organic acid transport 0.9263271939328276 1.610546832473818 0.1072785300959768 1.0 0.3755146991743082 3 O75915,P31749 2 +Er associated misfolded protein catabolic process 0.7598486627679791 1.607774170045795 0.107884647497972 1.0 0.3755146991743082 6 Q9BUN8,Q9NYU2 2 +Cardiac muscle cell differentiation 0.5711433423897134 1.6071199782759482 0.1080280515467646 1.0 0.3756191108607223 15 P35609,O75844,P78310 3 +Actin filament bundle organization 0.4415655820879579 1.6068233960809608 0.108093114417791 1.0 0.3756191108607223 42 Q9UQB8,P49593,Q9NWH9,Q8N5W9 4 +Positive regulation of protein containing complex assembly 0.4356615796995851 1.6062043386548326 0.1082290203960576 1.0 0.3758845075801473 49 Q9UQB8,P51608,Q9NWH9,P26038,O95429,Q71SY5,Q9UNE7,Q9NVN8 8 +Regulation of myeloid leukocyte mediated immunity 0.7093230887001492 1.6034252046606896 0.1088408100825595 1.0 0.3774508170719529 8 P09601 1 +Connective tissue development 0.5167326726193514 1.6008850317730192 0.1094023854446992 1.0 0.3791255003830028 24 O75844,O95747,P43490,O15173,Q96HY6,Q8N5W9 6 +Lymphocyte migration 0.6431464479298621 1.5976816259224482 0.1101138499872633 1.0 0.3811726144844193 11 P26038,O95747,P31749 3 +Insulin receptor signaling pathway 0.5034913650057148 1.592182411705854 0.1113437239965189 1.0 0.3837468740797055 27 Q9UQB8,P31751,P04899,P31749 4 +Attachment of spindle microtubules to kinetochore 0.5557842734824538 1.5892852494517595 0.1119960073942256 1.0 0.3855740407236318 17 Q9HBM1,Q99661,Q9BZD4,Q9H0H5,P14635 5 +Transmembrane receptor protein tyrosine kinase signaling pathway 0.3987874477197511 1.5875372017022835 0.1123910282658167 1.0 0.3862080393586857 71 Q9UQB8,P20936,P43490,P31749,P42574,Q9Y639,P31751,Q9NWH9,P04792,O14745,P40763,O95470,P04899,O15294,Q9UNE7 15 +Phosphatidylethanolamine metabolic process 0.9034599342903477 1.5868893812074871 0.1125377003391805 1.0 0.3862080393586857 4 Q8NCC3 1 +Proton transmembrane transport 0.4393078700912739 1.586707196804432 0.1125789756129331 1.0 0.3862080393586857 42 O75947,Q8TAD4,P13073,P21281,Q99623,Q9UDW1,P36543,P36542,P21283,O14745,P00846,O75251,Q9UHD1,P56385,P05141,P06576,Q9UJZ1 17 +Energy derivation by oxidation of organic compounds 0.3684758249040422 1.586647753019602 0.1125924456402185 1.0 0.3862080393586857 115 Q12931,P14927,Q13423,Q96I99,P40925,P00846,P14635,P10253,O75947,P51970,P14735,Q16851,O14949,P13073,Q9UDW1,P31749,O75489,P15954,P31751,P62136,Q15070,Q16795,Q9NZM5,P56385,Q16718,P06576,Q9UJZ1,P11177,P07954,Q9H3K2,O75306,P36542,P19404,O43676,Q15149,O75251,P04179,P34897,Q9H1K1 39 +Water homeostasis 0.7052552717661514 1.5856446210482478 0.1128199481347995 1.0 0.3867237527269948 8 Q15149,Q9NWH9,O76024,Q9Y3B8,P16949 5 +Neuron projection organization 0.5470622199590214 1.581190262534941 0.1138345411419896 1.0 0.3873564152381179 18 Q9H2U1,Q9UQB8 2 +Positive regulation of secretion 0.4402152406682939 1.5807957410293567 0.1139247486691772 1.0 0.3873564152381179 38 P04899,Q16822,P20339,Q8NE86 4 +Protein localization to extracellular region 0.4327417901959596 1.5789755570644362 0.1143416636743226 1.0 0.3885647279007928 49 Q16850,Q16822,P20645,Q8NE86 4 +Regulation of insulin secretion 0.5604089973147321 1.5759145230908551 0.1150455035204078 1.0 0.3890534440647503 16 Q16822,Q8NE86 2 +Development of secondary female sexual characteristics 0.745848375451261 1.5754037905034195 0.1151632700280358 1.0 0.3890534440647503 2 Q9H1B7 1 +Positive regulation of nitric oxide synthase activity 0.916215240158894 1.573451210035573 0.1156143772252358 1.0 0.3897432876669188 3 Q8WTV0,P31749 2 +Walking behavior 0.9156391105991454 1.57133604170194 0.1161046136347656 1.0 0.3911870493542744 3 O75844 1 +Cell cell signaling 0.3298809288352071 1.5704141283621225 0.1163187976780055 1.0 0.3913976468414167 155 O15439,Q9UQB8,Q8IZT6,P31749,Q7KZI7,O95793,O43768,Q16822,Q9Y639,Q8NE86,Q01469,P04899,Q13432,Q96A65 14 +Regulation of ion transmembrane transport 0.4292547219364709 1.5678946453698466 0.1169057216470763 1.0 0.3928380662478127 51 O75844,Q8TAD4,O75915,O95747,Q9BVC6,P35609 6 +Positive regulation of insulin secretion 0.7009626797461717 1.5668604644187931 0.1171473105547966 1.0 0.3933187446958586 8 Q16822 1 +Negative regulation of exocytosis 0.7497738169674005 1.5667490779457591 0.1171733542560833 1.0 0.3933187446958586 6 P04899 1 +Insulin secretion 0.5358411847542037 1.559931087984464 0.1187761669796467 1.0 0.3964961318313578 19 Q16822,Q8NE86 2 +Negative regulation of developmental growth 0.723141169735168 1.5570938138008277 0.1194482135724372 1.0 0.3977827112322621 7 Q9P265 1 +Peptidyl lysine trimethylation 0.5568921472237904 1.5557569930859656 0.1197658883692716 1.0 0.3982105419502795 16 P10412,Q03164,P16403,Q9NWS0,P46100,P51608 6 +Protein polymerization 0.3986968521471153 1.5552870262208782 0.1198777258208116 1.0 0.3982355596972303 69 Q9UQB8,Q6IBS0,P20936,O43633,Q12792,Q16763,P07196,Q9NWH9,Q9NSV4,Q96S59,Q9BSJ2,Q96CW5,Q9BPX3,P58546,O95429,P51608,P16949 17 +Regulation of neuronal synaptic plasticity 0.698299345493643 1.555195329216922 0.1198995563801765 1.0 0.3982355596972303 8 Q9Y639 1 +Regulation of neural precursor cell proliferation 0.655606254725457 1.5525842321556704 0.1205224950470627 1.0 0.3997981073267347 10 P04899 1 +Vascular associated smooth muscle cell proliferation 0.655545181083348 1.5522964848473886 0.120591298629374 1.0 0.3997981073267347 10 P04899,P09601,O95140 3 +Regulation of water loss via skin 0.7647517711493211 1.5512579240921438 0.1208398858093753 1.0 0.3997981073267347 5 Q9Y3B8,P16949,Q9NWH9 3 +Negative regulation of platelet derived growth factor receptor signaling pathway 0.7393501805054125 1.5453423003732536 0.1222634888417821 1.0 0.4024878355302464 2 O14745 1 +Regulation of platelet derived growth factor receptor signaling pathway 0.7393501805054125 1.5453423003732536 0.1222634888417821 1.0 0.4024878355302464 2 O14745 1 +Organic acid transmembrane transport 0.5047638850146247 1.5445575815892576 0.1224533131478635 1.0 0.4029026676475302 25 O75915,P31749,Q9H2D1,P31751,P33527,Q9BQT8,Q9UBX3 7 +Regulation of production of small rna involved in gene silencing by rna 0.7439899176523785 1.543151671605893 0.1227939800776192 1.0 0.4032134660842191 6 O75844,Q08209 2 +Positive regulation of smooth muscle cell apoptotic process 0.7627022406909999 1.5431136048945078 0.1228032143300528 1.0 0.4032134660842191 5 P04179,P42771,O95140 3 +Nervous system process 0.3650901208289971 1.5412152515582456 0.1232644067795007 1.0 0.4038876307243217 86 Q9UQB8,Q8NBU5,P07196,Q9Y5L4,Q08209,O76024,O14773,O75844,O75915,Q9Y639,Q92542,Q13432,P31749,Q01469,Q96P11,Q99797,P51608,O14745,P42574,P04179 20 +Regulation of phosphatase activity 0.5868348653484639 1.539454083741084 0.1236934792274633 1.0 0.4050429477257554 13 O75116,Q8IV63,Q9UHD1,O95429,P04899,P08238 6 +Cellular carbohydrate biosynthetic process 0.5526400392129941 1.5313547536459666 0.1256817401476015 1.0 0.4090487150989466 16 Q16822,P31749 2 +Transforming growth factor beta production 0.7350180505415135 1.5252870245807106 0.1271875227086294 1.0 0.4122494960894693 2 Q9Y5K6 1 +Negative regulation of transforming growth factor beta production 0.7350180505415135 1.5252870245807106 0.1271875227086294 1.0 0.4122494960894693 2 Q9Y5K6 1 +Endochondral bone morphogenesis 0.7391007554388779 1.523180546126465 0.1277135417587009 1.0 0.4128946762234705 6 O75844 1 +Negative regulation of ion transmembrane transport 0.544153152259064 1.5211847321381151 0.1282134857790364 1.0 0.4130305863310389 17 P35609,O75915,O95747 3 +Negative regulation of g protein coupled receptor signaling pathway 0.7385145569531034 1.520784631032379 0.1283138924586255 1.0 0.4131432519040091 6 P04899 1 +Positive regulation of leukocyte chemotaxis 0.6486264403481101 1.519669185081126 0.1285941400169852 1.0 0.413834556609197 10 O95747 1 +Positive regulation of protein modification process 0.3268620930514516 1.5176642479788935 0.1290990612975218 1.0 0.4148251771158028 155 O75832,Q03164,Q7KZI7,P36507,Q9P265,P14635,Q969T9,Q9Y376,Q9Y639,Q96HY6,Q13432,O43318,P31749,Q9UHR5,Q16763,P31751,Q9BUN8,Q9NZM5,Q13043,P51608,Q9UNE7 21 +Positive regulation of locomotion 0.3876077339147034 1.5145387777469963 0.1298892464611254 1.0 0.4165163545736648 74 Q96HY6,O95747,O95429,P31749,Q02952,P09601,P31751,Q8NE86,Q9NWH9,Q08209,P04792,P40763,Q8WTV0,P04899,P04179,Q5JRA6,Q13043,P49593 18 +Luteolysis 0.7324909747292392 1.513583440689905 0.1301315236290681 1.0 0.4166564218202693 2 P42574 1 +Heart development 0.3904242761308689 1.5107429411565858 0.1308539572413236 1.0 0.4177006501626479 72 O75844,Q6PI78,O95747,P78310,Q10567,Q9Y5P4,Q96T37,Q9UGN5,P42574,P35609,P80723,Q13043,P15924 13 +Positive regulation of protein acetylation 0.625183717890179 1.509722000726279 0.1311143750029035 1.0 0.4182007512932539 11 Q9P265 1 +Negative regulation of retinoic acid receptor signaling pathway 0.7314079422382643 1.5085666488774403 0.131409562468014 1.0 0.4188389588203133 2 A5YKK6 1 +Superoxide metabolic process 0.73543300386165 1.5081848162419016 0.1315072322644792 1.0 0.4189387812905762 6 P04899,P00374,Q9NY61 3 +Positive regulation of transporter activity 0.5418225039470065 1.5075088089131743 0.1316802876314868 1.0 0.4192785356052487 17 Q03164 1 +Positive regulation of leukocyte migration 0.5580391120042116 1.5062339390229975 0.132007129826392 1.0 0.4197202634278654 14 O95747 1 +Tissue migration 0.4262683850540564 1.5007826051099935 0.1334117992360501 1.0 0.4230849323839381 47 P57105,Q13630,P31749,Q16539,P14923,Q9NQW6,Q9NWH9,P09601,P04792,P58107,Q8WTV0,P42785,P51608,Q5JRA6,P49593 15 +Determination of adult lifespan 0.709226632644772 1.4982152485307725 0.1340773351186417 1.0 0.4249820752706345 7 O75844 1 +Myeloid leukocyte mediated immunity 0.6009888220547877 1.497244185830482 0.1343297319514913 1.0 0.4255684533576098 12 Q9H2U1,P09601 2 +Anoikis 0.6849112662459127 1.496442904804803 0.1345382759639819 1.0 0.4260153833683961 8 O43318,P31749 2 +Neural precursor cell proliferation 0.5173116103769902 1.4943382753156202 0.1350872258104907 1.0 0.427539219933553 20 P04899,O95456,Q8IZT6 3 +Response to temperature stimulus 0.4281511321595442 1.4917756111166425 0.1357579796174155 1.0 0.4292317893361851 43 P31749,Q9H2U1,P09601,O75190,Q13217,Q9UNE7,Q96EY1 7 +Response to arsenic containing substance 0.5996716433292322 1.490505933179461 0.1360912575862021 1.0 0.4296266325009948 12 Q9H2U1,Q9UER7,P09601,P07196 4 +Regulation of neurogenesis 0.4232475560034498 1.4902632358359895 0.1361550351020732 1.0 0.4296266325009948 49 Q9UQB8,Q6IBS0,Q8IZT6,Q9H2U1,P07196,Q9Y639,Q08209,Q9P265 8 +Proteasome assembly 0.7070583693435368 1.489024317432835 0.1364809653702305 1.0 0.4302250700687148 7 O95456,Q9BT73 2 +Iron ion homeostasis 0.5548615962637762 1.488501509035964 0.1366186844832881 1.0 0.4303537156937275 14 P30519,O75027 2 +Tripartite regional subdivision 0.8927313064740757 1.4871121671133694 0.1369851885540109 1.0 0.4307392831324828 3 Q9Y2W6 1 +Blastoderm segmentation 0.8927313064740757 1.4871121671133694 0.1369851885540109 1.0 0.4307392831324828 3 Q9Y2W6 1 +Regulation of monooxygenase activity 0.6823696747533166 1.4852693603070175 0.1374724849002553 1.0 0.4318414276916478 8 Q8WTV0,P31749 2 +Spindle elongation 0.7277250585604914 1.476634453391489 0.1397736510378284 1.0 0.4363541638842878 6 Q02241,Q9H0H5,O43663 3 +Negative regulation of chromatin binding 0.888768508486818 1.4725221418651937 0.140879932306613 1.0 0.4388336914573036 3 Q08209,Q7Z5K2 2 +Secondary alcohol metabolic process 0.4266250621909907 1.4695380928999735 0.1416868975888086 1.0 0.4409123072329903 41 Q16850,Q15392,P22570,Q8WTV0 4 +Negative regulation of phosphatase activity 0.7020190384560046 1.4676481044008671 0.1421998340590042 1.0 0.4420727485221826 7 O95429,P04899 2 +Ossification 0.4134438889948659 1.467242603605777 0.1423100711651119 1.0 0.4421977309726953 55 O75844,P62841,O95747,P31749,Q9H2U1,Q13951,Q96A33,Q8N5W9 8 +Regulation of extrinsic apoptotic signaling pathway via death domain receptors 0.6579372604045652 1.4664490310271312 0.142525997078212 1.0 0.4423190319032111 9 P09601 1 +Positive regulation of peptidyl lysine acetylation 0.657662178826117 1.4651945887448337 0.1428678355393819 1.0 0.4423190319032111 9 Q9P265 1 +Regulation of polysaccharide metabolic process 0.7013167553672446 1.4646674751329074 0.1430116628436804 1.0 0.4423190319032111 7 P31749 1 +Negative regulation of posttranscriptional gene silencing 0.7429047639730428 1.4642692650911753 0.1431203913992664 1.0 0.4423190319032111 5 O75844 1 +Positive regulation of mitochondrion organization 0.5409502648544949 1.4641122356237386 0.1431632846655373 1.0 0.4423190319032111 16 Q9UII2,Q8NE86 2 +Protein targeting 0.362192259242444 1.4640153543313663 0.1431897531216603 1.0 0.4423190319032111 99 O60830,O14925,Q99595,Q8IWJ2,P31751,Q9Y5L4,Q96RL7,P46379,P20645,O14737,O95429,Q9UII2,Q9Y584,Q9NS69,O95140 15 +Vitamin transport 0.6995051510137897 1.4569768924989863 0.1451227588805443 1.0 0.4461245390001385 7 P33527 1 +Circulatory system process 0.4024083507881109 1.4569569821462982 0.1451282551641248 1.0 0.4461245390001385 61 O15439,O75844,P14923,P78310,Q9NZ08,P09601,Q01469,P33527,P42785,P04899,P51608,P15924 12 +Pyridine containing compound biosynthetic process 0.7224603845411942 1.4550587814536795 0.1456529889461593 1.0 0.4467234370594621 6 P43490,O00764 2 +Protein deglycosylation 0.8839365874263336 1.4547260380227 0.1457451211373039 1.0 0.4467234370594621 3 O60502 1 +Regulation of long term synaptic potentiation 0.883829021262158 1.454329798457647 0.1458548927449059 1.0 0.4467234370594621 3 O95793 1 +Positive regulation of transcription regulatory region dna binding 0.7214783153202253 1.4510318743908253 0.1467709847694471 1.0 0.4482274111605288 6 Q96HY6 1 +Positive regulation of organ growth 0.7209547700097371 1.4488848412367628 0.1473697451461566 1.0 0.4497305804025293 6 P80723,P31749 2 +Regulation of notch signaling pathway 0.7384092861474034 1.4463264545779266 0.1480856591244022 1.0 0.4514789240518954 5 P40763,P31749 2 +Skin development 0.4383059224407846 1.4456775460218927 0.1482676651112024 1.0 0.4518156551699481 36 O75116,Q15392,O75844,P14923,Q9Y3B8,Q9NWH9,P42574,P18074,Q13043,P16949,Q9P0M6,P15924 12 +Regulation of cell size 0.4442690365729945 1.4432187862718804 0.1489588490660931 1.0 0.4533694840900775 35 Q6IBS0,P54105,Q96ST3,P26038,P58546,Q9P265 6 +Regulation of cell morphogenesis 0.4046213688300024 1.4426688438073678 0.1491137799174482 1.0 0.4535185001920848 59 Q7KZI7,Q9UQB8 2 +Negative regulation of potassium ion transport 0.86326612805214 1.4395801091649698 0.1499862304726622 1.0 0.455732944756684 4 P35609,O95747 2 +Negative regulation of potassium ion transmembrane transport 0.86326612805214 1.4395801091649698 0.1499862304726622 1.0 0.455732944756684 4 P35609,O95747 2 +Killing of cells of another organism 0.7354233554167471 1.4344016962470991 0.1514576638801705 1.0 0.4568535312757423 5 P39019,P81605 2 +Mitochondrial atp synthesis coupled proton transport 0.6098539588099374 1.4343393878728887 0.1514754353624932 1.0 0.4568535312757423 11 O75947,P00846,P56385,P06576,Q9UJZ1 5 +Cd4 positive or cd8 positive alpha beta t cell lineage commitment 0.7151624548736433 1.4332609712019335 0.1517832711305313 1.0 0.4568535312757423 2 P40763 1 +Heart valve morphogenesis 0.715162454873643 1.4332609712019335 0.1517832711305313 1.0 0.4568535312757423 2 O75116 1 +Positive t cell selection 0.7151624548736433 1.4332609712019335 0.1517832711305313 1.0 0.4568535312757423 2 P40763 1 +Negative regulation of calcineurin mediated signaling 0.7151624548736433 1.4332609712019335 0.1517832711305313 1.0 0.4568535312757423 2 Q9UHD1 1 +T helper cell lineage commitment 0.7151624548736433 1.4332609712019335 0.1517832711305313 1.0 0.4568535312757423 2 P40763 1 +Positive regulation of myotube differentiation 0.715162454873643 1.4332609712019335 0.1517832711305313 1.0 0.4568535312757423 2 Q16539 1 +Negative regulation of calcium mediated signaling 0.7151624548736433 1.4332609712019335 0.1517832711305313 1.0 0.4568535312757423 2 Q9UHD1 1 +Mitotic cytokinesis 0.4644050420092307 1.432296047034067 0.1520591139133185 1.0 0.4571910691660443 31 Q8WUX9,Q02241,P20936,O75116,Q14141,O43633,Q53EZ4,Q8WWK9,Q9NQW6,Q9H0H5,Q13432,P16949,P18583 13 +Sensory perception of pain 0.8777375871010853 1.4318865343353764 0.1521762965641007 1.0 0.4573256242292869 3 Q01469 1 +Positive regulation of epithelial cell migration 0.4805865068210087 1.4314013961327323 0.1523152085087007 1.0 0.4574784000035847 27 P31749,P09601,Q9NWH9,Q8WTV0,P49593 5 +Reactive oxygen species metabolic process 0.4426053748310427 1.4296250928340746 0.1528246496883745 1.0 0.4581388547443877 35 O75027,Q15067,Q9NY61,O75489,P00374,P42785,P04899,Q9UII2 8 +Positive regulation of cyclin dependent protein kinase activity 0.8603677400241496 1.4289332278184517 0.1530234259903067 1.0 0.4581388547443877 4 P14635,P31749 2 +Response to topologically incorrect protein 0.4095283736271498 1.428919490342362 0.1530273748267205 1.0 0.4581388547443877 55 P55145,O95140,Q8TCJ2,P04792,O76024,Q13217,Q9BUN8,P46379,Q96HY6,Q9UER7,Q9UNE7,Q9NYU2,Q9BS26 13 +Muscle tissue development 0.4192018156649059 1.4282925379224305 0.1532076747572803 1.0 0.4583992896881098 46 O75844,O95747,P78310,Q08209,Q9UGN5,P35609,P15924 7 +Mesenchyme development 0.4482489956043262 1.4277524723993826 0.1533631171181937 1.0 0.4583992896881098 34 O95747,P80723,Q96A65,Q8N5W9 4 +Ameboidal type cell migration 0.3956971268136242 1.4277491914316125 0.1533640618169858 1.0 0.4583992896881098 63 Q02952,Q8WTV0,P57105,Q13630,Q9NQW6,P04792,O95429,Q5JRA6,P31749,Q16539,Q7Z7K6,Q9NWH9,P42785,P49593,P14923,P09601,P58107,O95470,P51608 19 +Multicellular organismal response to stress 0.7152789644541349 1.425597011536841 0.1539846993879625 1.0 0.4596797277873923 6 P51608,P31749 2 +Peptidyl asparagine modification 0.6918199742422606 1.4243251165179436 0.1543523800914601 1.0 0.4603594368906373 7 P04843,Q8TCJ2,Q9NYU2,P04844 4 +Establishment or maintenance of bipolar cell polarity 0.5386461768131217 1.4232371880907737 0.1546674085422084 1.0 0.4608636231880622 15 Q7KZI7,P26038,O14745 3 +Icosanoid transport 0.732518542583373 1.4227958552866018 0.1547953432315258 1.0 0.4608662751634516 5 P33527 1 +Actin crosslink formation 0.8578275385533671 1.4196003149082823 0.155724073701688 1.0 0.4608662751634516 4 Q9UQB8 1 +Regulation of attachment of spindle microtubules to kinetochore 0.7133315345023796 1.417602040129464 0.1563069841922399 1.0 0.4620422744334285 6 Q9H0H5,P14635 2 +Regulation of phosphoprotein phosphatase activity 0.6267903134980389 1.416352917589932 0.1566722015731734 1.0 0.4623056531416456 10 P04899,Q8IV63 2 +Regulation of arp2 3 complex mediated actin nucleation 0.7307814791142491 1.415853363065787 0.1568184419018714 1.0 0.4623056531416456 5 P53365,P53367 2 +Atp synthesis coupled proton transport 0.585078025910799 1.4157139862926074 0.1568592617242452 1.0 0.4623056531416456 12 O75947,P00846,P56385,P06576,Q9UJZ1 5 +Intermediate filament bundle assembly 0.8732394366197158 1.4153088718393108 0.1569779549202725 1.0 0.4623056531416456 3 P58107,P07196 2 +Response to peptide hormone 0.3682997147895475 1.4152968961725236 0.1569814646686373 1.0 0.4623056531416456 80 Q9UQB8,P31749,Q16822,P07196,P31751,P35609,P04899 7 +Regulation of glucan biosynthetic process 0.7297097442523317 1.4115691689181225 0.1580768557912624 1.0 0.4641373609606272 5 P31749 1 +Regulation of glycogen metabolic process 0.7297097442523317 1.4115691689181225 0.1580768557912624 1.0 0.4641373609606272 5 P31749 1 +Regulation of nitric oxide synthase activity 0.7293146933883925 1.409989825226995 0.1585426873048672 1.0 0.4647838377764041 5 Q8WTV0,P31749 2 +Methylation 0.3560088172724348 1.409933048589824 0.1585594530520073 1.0 0.4647838377764041 89 O75844,Q7L592,Q96P11,Q03164,P10412,P16403,Q9BV86,P51608,Q9UJA5,Q9NWS0,Q9Y2W6,Q86YP4,Q96T37,P46100,Q7L2J0,P22061,Q7Z4G4,Q52LJ0 18 +Fatty acid transmembrane transport 0.7113776194987829 1.409578198894826 0.1586642681156542 1.0 0.4648752616622927 6 P31751,P31749 2 +Response to chemokine 0.7289836046900844 1.4086661287137423 0.1589339149239688 1.0 0.4650839011448091 5 O95747 1 +Lipoprotein localization 0.8548499972787771 1.4086586731875936 0.158936120523327 1.0 0.4650839011448091 4 A6NIH7 1 +Regulation of transcription by rna polymerase i 0.5036429567366343 1.408341020910018 0.1590301144396013 1.0 0.4650839011448091 20 Q8TED0,O75844,Q9NZM5,Q9P0M6 4 +Multicellular organism aging 0.6240790509640253 1.403494292136532 0.1604694928665759 1.0 0.4688590365384362 10 O75844 1 +Negative regulation of protein localization 0.4192292512293583 1.398785623851909 0.1618772786055791 1.0 0.4720984467046773 39 O75116,O75608,O95429,O95602,Q96ST3,Q10713,Q16836,Q08209,P35609,Q16850,P49593,Q9NQ48 12 +Positive regulation of epidermal cell differentiation 0.7084256225603476 1.3974516315807546 0.1622778020498434 1.0 0.4721888418879713 6 Q9Y3B8 1 +Positive regulation of epidermis development 0.7084256225603476 1.3974516315807546 0.1622778020498434 1.0 0.4721888418879713 6 Q9Y3B8 1 +Oligodendrocyte development 0.662300858435457 1.3968530131199324 0.1624577766607793 1.0 0.4721888418879713 8 Q96P11,Q92542 2 +Regulation of leukocyte migration 0.4861933444873145 1.3961938827610847 0.1626561183253623 1.0 0.4721888418879713 24 O95747,P09601,P31749,Q8NE86 4 +Regulation of inclusion body assembly 0.6842094297744794 1.3919520544973918 0.163936917200314 1.0 0.4739270830500695 7 O75190 1 +Oligopeptide transport 0.8667388949078952 1.391346481874567 0.1641203850256314 1.0 0.4739270830500695 3 O15439,P33527 2 +Tripeptide transport 0.8667388949078952 1.391346481874567 0.1641203850256314 1.0 0.4739270830500695 3 O15439,P33527 2 +Cell morphogenesis involved in neuron differentiation 0.3749848979228959 1.3882484286942751 0.1650614100413046 1.0 0.4740612583008244 75 Q9UQB8,Q6IBS0,Q8TEY7,Q7KZI7,Q9H2U1,Q96ST3,P07196,Q9Y639,Q08209,Q9P265 10 +Mammary gland involution 0.7054151624548703 1.3880503452458153 0.1651217152022188 1.0 0.4740612583008244 2 P07384 1 +Regulation of hormone secretion 0.4900651226593153 1.385926827034614 0.1657692481504775 1.0 0.4745091834320681 22 Q16822,Q8NE86 2 +Cell death in response to oxidative stress 0.4922659809962055 1.3858748496631652 0.1657851217375898 1.0 0.4745091834320681 21 O75915,P31749,Q969S3,Q9NWH9,P04792,P04179 6 +Regulation of peptide transport 0.5073286611237127 1.3848279715330758 0.1661050757354754 1.0 0.4748822499367486 19 Q16822,Q8NE86 2 +Regulation of potassium ion transport 0.5781103634735771 1.3799296314559 0.1676083121156457 1.0 0.4769991096999683 12 P35609,O95747 2 +Response to zinc ion 0.8454390972834145 1.3740655542612383 0.1694213319551298 1.0 0.480011855554889 4 Q8TAD4 1 +Plasma membrane organization 0.4881576069577013 1.373440339991945 0.1696154962155072 1.0 0.4801199492185196 22 Q9UQB8,P31751,P31749 3 +Regulation of nervous system process 0.6174699872091634 1.3721273794604143 0.1700237874632368 1.0 0.4804491154186625 10 Q9UQB8 1 +Regulation of epidermis development 0.6562969710489329 1.3703479799741631 0.1705783023177434 1.0 0.4812472747248579 8 Q9Y3B8,Q9P0M6 2 +Appendage development 0.5550932751803755 1.3697540457804598 0.1707636914992989 1.0 0.4813765413706028 13 O95747,P46100 2 +Histone h3 acetylation 0.6169614627559814 1.3697127084700147 0.1707766000427859 1.0 0.4813765413706028 10 Q96ST3,Q969T9,Q03164 3 +Transcription by rna polymerase i 0.4787997710573452 1.367614371918083 0.1714328154214042 1.0 0.482795181342884 25 O75844,O15160,Q8TED0,O95602,Q9NWS0,Q9NZM5,P18074,Q9H583,Q9P0M6 9 +Triglyceride biosynthetic process 0.8435484093827299 1.3671142217745782 0.1715895062213892 1.0 0.4828051882540809 4 Q16822 1 +Ventricular cardiac muscle tissue development 0.7184753371249204 1.366627056712337 0.1717422319953541 1.0 0.4828051882540809 5 O75844 1 +Positive regulation of fibroblast migration 0.7183781349548806 1.3662379727463565 0.171864282498019 1.0 0.4829332797919412 5 O95429,P31749 2 +Cellular response to oxygen containing compound 0.3191251399918276 1.3640136079556502 0.1725632828740324 1.0 0.4836920132920712 176 Q9UQB8,O95747,Q86U42,Q9H2U1,Q16822,Q08209,P33527,Q6IAA8,Q8WTV0,P35609,P04899,Q6IBS0,Q96ST3,Q92542,P26038,P31749,Q9NWH9,P31751,P40763,P43490,P14923,P00374,Q9NWS0,O14745,P04179,O15294 26 +Regulation of hormone levels 0.4005426378254279 1.3545831654330194 0.175550400026117 1.0 0.4867919305072036 56 O75844,Q8TAD4,O43768,Q16822,Q8NE86,P09455,O95470,Q9UNE7 8 +Regulation of protein localization to cell surface 0.6526419145569722 1.3542028324455446 0.1756716756218579 1.0 0.4869143809817432 8 P31749 1 +Endothelial cell proliferation 0.5157368916800054 1.3539044396507898 0.1757668669405636 1.0 0.4869644571578407 17 Q9UII2,Q8WTV0,P31749 3 +Regulation of cardiac muscle cell action potential 0.7150392894379503 1.3528710357623026 0.176096834016215 1.0 0.4876646534992901 5 P14923,P78310 2 +Response to heat 0.4440860525053848 1.351719983826247 0.1764649097261226 1.0 0.4882998308697163 33 P31749,Q9H2U1,P09601,O75190,Q9UNE7,Q96EY1 6 +Alcohol biosynthetic process 0.4330733179084549 1.3516701126883304 0.1764808701369484 1.0 0.4882998308697163 35 Q15392,P00374,Q16822,Q15800,Q16850 5 +Cell part morphogenesis 0.353516119485247 1.350017008136189 0.1770105272944895 1.0 0.4893364576783742 98 Q9UQB8,Q6IBS0,Q8TEY7,Q13596,Q7KZI7,Q9H2U1,Q96ST3,Q9Y639,P07196,Q04837,Q9Y5P4,Q08209,Q9P265 13 +Activation induced cell death of t cells 0.8383581981662693 1.3480304145520603 0.1776486004748279 1.0 0.4904561711403862 4 Q96EY1 1 +Long term synaptic potentiation 0.6733718316421197 1.3457985946853026 0.1783674787818823 1.0 0.4918719291682442 7 O95793,P51608,Q9Y639 3 +Positive regulation of cell size 0.6960288808664226 1.344516360910808 0.1787814694178049 1.0 0.4927220418612048 2 P08238 1 +Regulation of fibroblast migration 0.6310805588953396 1.3437006269759175 0.1790452145133654 1.0 0.4932336319534857 9 O95429,P31749 2 +Regulation of excretion 0.853632160024703 1.3430249245400865 0.1792639033067615 1.0 0.4936207088874367 3 P04899 1 +Positive regulation of peptide secretion 0.6104429143933345 1.3387472312857995 0.1806529746476997 1.0 0.4950706952801978 10 Q16822 1 +Response to osmotic stress 0.5129443470876441 1.337416301638977 0.1810867862129832 1.0 0.4952147571480466 17 Q9Y376,O95747,P42574 3 +Regulation of amyloid beta clearance 0.8519361597426858 1.336772419209481 0.1812969346540369 1.0 0.4952147571480466 3 Q16850 1 +Ear development 0.4922039781030441 1.3361818084430024 0.181489855565502 1.0 0.4952147571480466 20 O95747 1 +Positive regulation of epithelial cell differentiation 0.6708403922155799 1.335010871566567 0.1818727883042339 1.0 0.4960452636513749 7 Q9Y3B8 1 +Negative regulation of production of mirnas involved in gene silencing by mirna 0.8510868970661725 1.3336415992782913 0.1823213427898937 1.0 0.4966992006389593 3 O75844 1 +Positive regulation of vascular associated smooth muscle cell apoptotic process 0.8510629585473792 1.333553350509319 0.1823502799701255 1.0 0.4966992006389593 3 O95140 1 +Positive regulation of monocyte chemotaxis 0.6931407942238232 1.3311246075664307 0.1831480132895147 1.0 0.4980127383447134 2 Q8NHP6 1 +Regulation of monocyte chemotaxis 0.6931407942238232 1.3311246075664307 0.1831480132895147 1.0 0.4980127383447134 2 Q8NHP6 1 +Protein k63 linked deubiquitination 0.5888080086493523 1.3305034176363804 0.1833524610662429 1.0 0.4980127383447134 11 O00487,Q9NZM5 2 +Chaperone mediated protein complex assembly 0.5683539594768168 1.3297619243073304 0.1835967247636389 1.0 0.4980127383447134 12 Q9UNE7,O95456,Q9BT73 3 +Histone h3 k14 acetylation 0.7089376183654681 1.328433943656372 0.1840347921744474 1.0 0.4980127383447134 5 Q03164 1 +Circadian regulation of gene expression 0.517213685171912 1.327028919611999 0.1844991163803642 1.0 0.4980127383447134 16 Q9BQG2,O15294,P43490,Q03164 4 +Regulation of transport 0.317123920736203 1.3263778565033353 0.1847145697059466 1.0 0.4980127383447134 264 O95747,Q03164,Q9C0E2,Q16822,Q08209,Q8WTV0,P36507,Q16850,P04899,P35609,Q92783,Q8IWJ2,O75844,Q8TAD4,Q4V328,O75915,Q9Y376,Q9P253,Q8NE86,P26038,O95429,Q13432,P31749,O43768,P31751,Q01469,Q9UII2,P20339,P49593,Q9Y282,P14923,P09601,Q9BVC6,O14737,Q9Y3B8,Q16630 36 +Positive regulation of sprouting angiogenesis 0.6920577617328485 1.326103327280555 0.1848054741881784 1.0 0.4980127383447134 2 Q07157 1 +Protein localization to chromosome telomeric region 0.5039812019477736 1.3222923802416693 0.1860708091135319 1.0 0.4992992302349513 18 Q9NVN8,O14773 2 +Negative regulation of transporter activity 0.524786906528769 1.3200443946947955 0.1868201961832025 1.0 0.5006717821310446 14 P35609,O95747 2 +Regulation of ion transport 0.3734101601016966 1.3192315930371137 0.1870916992857205 1.0 0.5009741260772008 72 O75844,Q8TAD4,O95747,O75915,P31749,Q9BVC6,P35609,P04899 8 +Negative regulation of autophagy 0.4891581196198774 1.316947930725825 0.1878560786435095 1.0 0.5015313873499999 20 P31749,P10619,Q04637,Q9NWH9,P09601,P40763 6 +Regulation of leukocyte chemotaxis 0.5859881544132235 1.3165703058167515 0.1879826976669876 1.0 0.5015313873499999 11 O95747 1 +Response to ketone 0.4284848335983651 1.3141189345189177 0.1888061831784626 1.0 0.5015313873499999 35 Q969T9,P31749,Q96ST3,Q16822,P07196,P26038 6 +Regulation of kidney development 0.8455225528879625 1.3131305742332382 0.1891389529826193 1.0 0.5015313873499999 3 O95747 1 +Metanephric mesenchyme development 0.8455225528879625 1.3131305742332382 0.1891389529826193 1.0 0.5015313873499999 3 O95747 1 +Kidney mesenchyme development 0.8455225528879625 1.3131305742332382 0.1891389529826193 1.0 0.5015313873499999 3 O95747 1 +Organ growth 0.4885281242921331 1.3129688932413368 0.1891934302800813 1.0 0.5015313873499999 20 O75844,P80723,Q9UGN5,P31749 4 +Regulation of muscle hypertrophy 0.604922885748534 1.3125094724257838 0.1893482920902838 1.0 0.5015313873499999 10 Q12792,Q08209,Q9UGN5,P58546 4 +Branching involved in blood vessel morphogenesis 0.8286843510240027 1.3124598203282802 0.1893650344381374 1.0 0.5015313873499999 4 Q96T37 1 +Positive regulation of fat cell differentiation 0.643080873827064 1.3119433484462206 0.1895392499321087 1.0 0.5017823161724672 8 Q16539,Q13043,P31749 3 +Regulation of superoxide anion generation 0.8448411813025314 1.3106192355799622 0.1899864371620316 1.0 0.5023731583916053 3 P04899 1 +Dna strand elongation involved in dna replication 0.5844500199455935 1.3089689198313188 0.1905448789461621 1.0 0.5024840933934397 11 P18858 1 +Release of cytochrome c from mitochondria 0.5078655033650481 1.3074157449722252 0.1910715528300191 1.0 0.5028779725206965 17 O75832,O75223,P31749,O14737,Q9Y3B8 5 +Positive regulation of smooth muscle cell proliferation 0.6037646356646369 1.3070026608511718 0.191211807796789 1.0 0.5028779725206965 10 P04899,P31749 2 +Protein localization to early endosome 0.7029752587568664 1.3045457969009435 0.1920475553979028 1.0 0.5045075499507128 5 O75116,P26038 2 +Regulation of cell development 0.3676106342267701 1.303126384176769 0.1925316173608529 1.0 0.5050455471609577 75 Q9UQB8,Q6IBS0,Q96G23,Q8IZT6,P31749,Q9H2U1,P07196,Q9Y639,Q08209,Q9P265,Q8N5W9 11 +Peripheral nervous system axon regeneration 0.8422812401311908 1.3011847707405535 0.1931952168292534 1.0 0.5062007070342109 3 P07196 1 +Regulation of superoxide metabolic process 0.8256039358432405 1.3011342774860877 0.1932124966665265 1.0 0.5062007070342109 4 P04899,Q9NY61 2 +Cell recognition 0.4786842052505606 1.298052836875874 0.1942691793227882 1.0 0.5077073925818095 21 P26038,Q9Y639,Q8WTV0 3 +Positive regulation of muscle cell apoptotic process 0.682140694289576 1.289315042765998 0.1972885834100668 1.0 0.5134892992162954 6 P04179,P42771,O95140 3 +Kinetochore assembly 0.6841155234657006 1.2892945688212964 0.197295698431855 1.0 0.5134892992162954 2 P50748 1 +Regulation of secretion 0.3662789920133384 1.287762535539973 0.1978286373786237 1.0 0.5143324532573378 75 O43768,Q16822,P09601,Q8NE86,Q16850,P04899,P20339 7 +Negative regulation of ion transmembrane transporter activity 0.5398009415238677 1.2876608799771967 0.1978640368961155 1.0 0.5143324532573378 13 P35609,O95747 2 +Amyloid precursor protein metabolic process 0.4977912310518145 1.284926109741263 0.1988181059729381 1.0 0.5153273896195121 18 O75116,Q15392,Q9NY61,Q92542,O95197,P42574,Q16799 7 +Steroid catabolic process 0.8371253159985383 1.2821872574599664 0.1997769651359466 1.0 0.5161177405353385 3 Q8NBQ5,Q8WTV0 2 +Appendage morphogenesis 0.5788790453328744 1.2814312385486366 0.2000422376306028 1.0 0.5163804940309183 11 O95747,P46100 2 +Cell projection organization 0.3193208756632107 1.2768928727163902 0.2016400707476657 1.0 0.518236475917134 206 P55145,Q9UQB8,A6NIH7,Q8TEY7,Q7KZI7,Q9H2U1,P07196,Q08209,P35609,Q9P265,Q6IBS0,Q14141,Q13596,Q12756,Q96ST3,Q9Y639,Q9NQW6,O95429,Q96A65,Q9H4M9,Q01968,P31749,P53365,O15439,P20339,Q9Y3P9,Q14195,A0AVF1,P00374,P42574,P51608 31 +Regulation of mononuclear cell migration 0.5125884302769372 1.274853940946303 0.2023609441881417 1.0 0.518236475917134 15 O95747,P31749 2 +Ceramide transport 0.6565409917249725 1.27404123880729 0.2026488015265335 1.0 0.518236475917134 7 Q9Y5P4 1 +Coenzyme a metabolic process 0.6343534321664753 1.2733461314157872 0.2028952436596698 1.0 0.518236475917134 8 Q9HCC0 1 +Chloride transport 0.6151430038713068 1.2706840524496454 0.2038410712446241 1.0 0.5196013418807254 9 P54105,Q9C0H2 2 +Positive regulation of glycoprotein metabolic process 0.6943667630240014 1.2700466902003948 0.2040679992348524 1.0 0.5198375179030261 5 P62820,Q92542,P35610 3 +Circulatory system development 0.336829338223679 1.2685595739336948 0.2045981903919584 1.0 0.5206904369749399 132 Q6PI78,O95747,P78310,Q9Y5P4,P35609,O75844,Q96PU8,P04792,Q96T37,Q9UGN5,P20936,P31749,Q9NZ08,Q10567,P42785,Q9UII2,P42574,Q13043,P14923,P09601,P80723,O95470,P51608,P15924 24 +Cellular iron ion homeostasis 0.5759391712367689 1.266896513323236 0.2051922956145038 1.0 0.5217009245891064 11 O75027 1 +Carbohydrate derivative transport 0.506447243398225 1.2647090892645072 0.2059756305025151 1.0 0.5231416456125826 16 Q9NZD2,O15439,Q8WTV0 3 +Mismatch repair 0.5754350296430324 1.2644039243775052 0.2060850850436777 1.0 0.5232091785145884 11 P18858 1 +Epithelial cell proliferation 0.4035303369210007 1.2637764440713093 0.2063102782990247 1.0 0.5235703766800812 41 O95747,P31749,P09601,Q8WTV0,Q9UII2 5 +Meiotic spindle organization 0.8150440178612973 1.2623202828574784 0.2068335611082523 1.0 0.5239148896728262 4 Q8IZT6 1 +Epithelial cell differentiation 0.3448917673475462 1.261649550050165 0.2070749179599436 1.0 0.5239148896728262 90 O95747,P31749,Q16822,Q9NWH9,P31751,P26038,P80723,P46100,P42574,Q9Y3B8,Q13043,O14773 12 +Regulation of response to reactive oxygen species 0.6751905936965167 1.2606951210104085 0.2074187124744615 1.0 0.5239148896728262 6 P00374,Q9NWH9,P32322 3 +Regulated exocytosis 0.449457895821163 1.2601910427342309 0.207600453336618 1.0 0.5239148896728262 29 P56545,Q9P253,P09601,O43760,O15439,O95721,P20339,P04899 8 +Regulation of potassium ion transmembrane transporter activity 0.5935273439262324 1.2583167986249493 0.2082772082780084 1.0 0.5250482753193014 10 P35609,O95747 2 +Magnesium ion transport 0.8305862986131849 1.2581041337144072 0.208354098567717 1.0 0.5250482753193014 3 Q8IUH4 1 +Regulation of dna binding 0.4681820747041828 1.257411348131853 0.2086047220990932 1.0 0.5251603927030597 23 O75844,Q96ST3,Q96HY6,P09601 4 +Regulation of long chain fatty acid import across plasma membrane 0.8297243754797389 1.254930739022564 0.2095039040151287 1.0 0.5260328676353299 3 P31749 1 +Long chain fatty acid import across plasma membrane 0.8297243754797389 1.254930739022564 0.2095039040151287 1.0 0.5260328676353299 3 P31749 1 +T cell migration 0.6300326098280709 1.2542337111465838 0.209757070112184 1.0 0.5261172866241599 8 O95747 1 +Protein localization to chromatin 0.5129644322842535 1.2536344739297538 0.2099748948627147 1.0 0.5261172866241599 14 Q8WUX9,Q7Z5K2,Q9P0M6 3 +Positive regulation of nitric oxide metabolic process 0.6902680696735484 1.2536196326942783 0.2099802917790438 1.0 0.5261172866241599 5 P04179,P50570,P31749 3 +Visual behavior 0.8290037642854171 1.2522778314746603 0.2104686438543732 1.0 0.5271317006332855 3 Q9Y639 1 +Regulation of mitochondrion organization 0.4208236406848975 1.2514200611628756 0.2107812618970159 1.0 0.5272871979468141 35 O14737,Q9UII2,P31749,Q8NE86 4 +Regulation of sodium ion transport 0.5330053136211486 1.251151023058739 0.2108793831427906 1.0 0.5273237327380516 13 O95747 1 +Positive regulation of hormone secretion 0.5524818297374523 1.248056843359073 0.2120102412222584 1.0 0.5287109974610671 12 Q16822 1 +Intrinsic apoptotic signaling pathway in response to oxidative stress 0.5117159230354625 1.2466194246037865 0.2125370758700384 1.0 0.5288576312272226 14 P04792,Q969S3,O75915,P31749 4 +Negative regulation of macroautophagy 0.5910425183935797 1.2464978703290115 0.2125816705819909 1.0 0.5288576312272226 10 P31749 1 +Regulation of muscle adaptation 0.5715823651326036 1.245354985872554 0.2130012919987096 1.0 0.5294843140471861 11 Q12792,Q08209,Q9UGN5,P58546 4 +Potassium ion transport 0.4968698306445424 1.242430396229753 0.2140778064981083 1.0 0.5312780678569995 17 P35609,O95747 2 +Proximal tubule development 0.6736462093862778 1.2408277620271313 0.214669383142491 1.0 0.5312780678569995 2 P35610 1 +Generation of precursor metabolites and energy 0.3109708202311322 1.2404735792476138 0.2148002806606748 1.0 0.5312780678569995 171 Q12931,P14927,Q96I99,P00846,Q9BRR6,P14635,P10253,O75947,Q13630,P22570,P51970,P14735,P29401,Q16851,O14949,Q99623,P13073,Q9UDW1,Q15067,P31749,O75489,P15954,P06733,P31751,P62136,Q15070,Q16795,Q9NZM5,P40763,P56385,Q9UII2,Q16718,P04406,P06576,Q9UJZ1,P11177,P07954,Q9H3K2,P09669,O75306,P36542,P37837,P23368,O43676,Q15149,O75251,P04179,O15294,P34897,P35610,P54619 51 +Phosphatidylcholine biosynthetic process 0.670107700445743 1.2397635243594156 0.2150628732974455 1.0 0.5314704430528654 6 Q01469 1 +Multicellular organismal signaling 0.4768617239267675 1.2392564769142096 0.2152505312138495 1.0 0.5316245030659918 20 O75844,P78310,P14923,P15924 4 +Regulation of cyclase activity 0.686143969107183 1.2370914949003438 0.2160531169410684 1.0 0.5326715821733545 5 Q16539,P04899 2 +Peptidyl amino acid modification 0.3175589862172815 1.2370362153618866 0.2160736379253651 1.0 0.5326715821733545 211 O95747,Q03164,Q7KZI7,Q9Y237,P36507,O95302,Q9P265,O75844,Q969T9,O75448,P16403,Q9Y3C6,Q96ST3,Q9Y376,Q9UGN5,P04844,O95429,Q13432,Q9BU89,O43318,P31749,Q9NWH9,P31751,Q8TCJ2,Q9BX68,Q99986,Q13043,P49593,Q9NYU2,Q9NVN8,Q7L592,P10412,Q9BV86,Q9NWS0,P46379,P46100,P51608,O15294 38 +Lipopolysaccharide mediated signaling pathway 0.6077114001380439 1.2366229043924488 0.216227112548736 1.0 0.5326715821733545 9 Q8WTV0 1 +Regulation of heart contraction 0.476374498851619 1.2361775934144703 0.2163925575347884 1.0 0.5326715821733545 20 O75844,P78310,P14923,P15924 4 +Regulation of long chain fatty acid import into cell 0.8071081642624657 1.2331692862473065 0.217512611773111 1.0 0.5335611311019806 4 P31749 1 +Regulation of anatomical structure size 0.345339326613787 1.2328164855898849 0.2176442392922806 1.0 0.5335659952866121 84 O75116,Q9UQB8,P20936,Q6IBS0,P54105,Q12792,Q96ST3,P07196,P26038,O14745,Q9BPX3,P58546,P35609,O95429,P04179,Q9P265,P20339 17 +Positive regulation of cardiac muscle cell proliferation 0.6718411552346533 1.2324796421522202 0.2177699667173898 1.0 0.5335659952866121 2 Q16539 1 +Regulation of cardiac muscle cell proliferation 0.6718411552346533 1.2324796421522202 0.2177699667173898 1.0 0.5335659952866121 2 Q16539 1 +Kinetochore organization 0.6848572461149107 1.231935045976501 0.2179733486682296 1.0 0.5338151912604931 5 P50748,Q9BZD4,Q9NTJ3,O95347 4 +Positive regulation of hydrogen peroxide metabolic process 0.6714801444043285 1.230810355650115 0.2183938015085655 1.0 0.5340582737122707 2 P04179 1 +Regulation of hydrogen peroxide biosynthetic process 0.6714801444043285 1.230810355650115 0.2183938015085655 1.0 0.5340582737122707 2 P04179 1 +Positive regulation of chromatin binding 0.82199337913032 1.226480417249161 0.2200179401661888 1.0 0.53597363877443 3 Q71SY5 1 +Positive regulation of mitochondrial membrane potential 0.8046348512519392 1.224088381100219 0.2209188886369737 1.0 0.5377339486714927 4 P31749 1 +Epithelial tube morphogenesis 0.4439118020557639 1.2197548819362751 0.222557809693652 1.0 0.5408891495018163 29 Q13043,O95747,Q96T37,Q9NWH9 4 +Sulfate transport 0.8197736832371851 1.218316877661829 0.2231035787769286 1.0 0.5415901562466465 3 Q9H0H5 1 +Plasminogen activation 0.6813653555587008 1.2179428147681872 0.2232457045564977 1.0 0.541726894146705 5 Q15392 1 +Endomembrane system organization 0.3293271325247498 1.2155356546392886 0.2241618586204592 1.0 0.5431055782378486 137 Q9UQB8,P57088,Q9Y5P4,O43760,O95197,Q6IAA8,P36507,Q5JTV8,Q8IWJ2,Q92783,O75844,Q8N4V1,Q9P253,Q5JRA6,P31749,P31751,Q7Z392,Q99986,Q96A33,Q9NPA0,Q8NFQ8,O95721,O15260,Q8WUX9,O43633,Q14789,O14745,Q9NXE4,P46379,O00161,O94901,Q86XL3 32 +Mitotic spindle midzone assembly 0.8020231213872825 1.2145019449819183 0.2245561075641973 1.0 0.5434745568054601 4 Q02241,Q9H0H5,O43663 3 +Response to growth hormone 0.6802538629978176 1.213489471998176 0.2249427371118508 1.0 0.5437551462956456 5 P31749 1 +Peripheral nervous system myelin maintenance 0.8180012836908062 1.2118002032600004 0.2255888705009598 1.0 0.5446914448730634 3 P31749 1 +Negative regulation of establishment of protein localization 0.4649494873650598 1.2091541621619342 0.2266036241531903 1.0 0.5463003210270011 21 O75608,Q9GZP9,Q16836,Q08209,Q16850,O95429,P49593 7 +Negative regulation of dna metabolic process 0.3977323860566898 1.2089350181632963 0.2266878113859269 1.0 0.5463003210270011 38 Q03164,P16403,Q9UBB9,P07305,Q9NVN8 5 +Positive regulation of mitotic cell cycle spindle assembly checkpoint 0.6664259927797797 1.207453137620052 0.227257682045473 1.0 0.5466285270519786 2 Q9Y6G9 1 +Tube formation 0.4717638105766503 1.2070439139825877 0.2274152325304588 1.0 0.5466285270519786 20 Q13043,O95747 2 +Histone h4 k16 acetylation 0.6011933647732267 1.206752598767283 0.2275274358797108 1.0 0.5466285270519786 9 Q03164 1 +Positive regulation of supramolecular fiber organization 0.3973135331747994 1.2056575764125297 0.227949549014812 1.0 0.5468593846998702 39 Q9UQB8,Q9NWH9,P35609,P51608,P49593 5 +Cell migration involved in sprouting angiogenesis 0.6399220433292135 1.203165134245362 0.2289124241166091 1.0 0.5480542623906376 7 P09601,P31749 2 +Post embryonic development 0.4999864988869849 1.202995638709435 0.2289780082652046 1.0 0.5480542623906376 15 P04179,P22033,Q96A33,P46100,O95470,P51608,Q9NX62 7 +Chondrocyte differentiation 0.5814629172905794 1.20093846210747 0.229775073137235 1.0 0.5491050372634343 10 O95747,Q8N5W9 2 +Establishment of protein localization to chromatin 0.6768507508111752 1.1998562718857106 0.2301951652482503 1.0 0.5491050372634343 5 Q9P0M6 1 +T cell apoptotic process 0.5430792203700674 1.199646288307226 0.2302767413551167 1.0 0.5491050372634343 12 Q96EY1 1 +Signal transduction by p53 class mediator 0.3944529460730529 1.1959526928615856 0.2317150206195684 1.0 0.5514695213689992 45 O75844,P62841,P31749,Q9BVC6,Q9NZM5,P46379,P46100,Q9NWT1 8 +Cellular response to lipid 0.3379984279905297 1.1940825293855264 0.2324456865053501 1.0 0.5527917380771302 86 Q6IBS0,Q969T9,O95747,O15173,P31749,Q16822,P26038,Q8WTV0,Q96HY6,Q9UER7 10 +Regulation of generation of precursor metabolites and energy 0.4189209972260282 1.192855584011455 0.2329259367942144 1.0 0.5535168855546369 34 P31749,P31751,Q9NZM5,P40763,O15294,P14635 6 +Glucocorticoid metabolic process 0.7955697435853017 1.1908280663926418 0.2337210883455518 1.0 0.5545715715196596 4 P51608,Q9UNE7 2 +T helper 17 type immune response 0.6624548736462057 1.1891195042647815 0.2343926442918804 1.0 0.5552867832198204 2 P40763 1 +Activation of protein kinase c activity 0.6624548736462057 1.1891195042647815 0.2343926442918804 1.0 0.5552867832198204 2 Q99623 1 +Regulation of phospholipase c activity 0.6624548736462057 1.1891195042647815 0.2343926442918804 1.0 0.5552867832198204 2 Q99623 1 +Activation of phospholipase c activity 0.6624548736462057 1.1891195042647815 0.2343926442918804 1.0 0.5552867832198204 2 Q99623 1 +Mitochondrial electron transport ubiquinol to cytochrome c 0.6741259075426678 1.188942646151906 0.2344622369439406 1.0 0.5552867832198204 5 P14927,Q9UDW1 2 +Cytoplasmic translation 0.3411265313377053 1.1885087884500412 0.2346330194477781 1.0 0.5554828964354223 111 P62906,Q9H2U1,P47914,P18077,P11940,P42345,P62249,P62910,Q9Y3U8,P62899,P62753,P62424,P62841,P55039,P32969,P63173,P62263,P62081,P15880,P30050,Q9ULC4,P62241,Q9BQC3,P35268,P62244,P62829,P62269,P39019,P62750,Q04637,P61247,Q7L2H7,Q9H074,P08865,P14618,Q00839,Q7Z478,P62277,P05388,P46781,P61353,P42766,P18124,P26373,Q14152,O43583,P05387 47 +Negative regulation of cell activation 0.5012115459012887 1.1876054251357109 0.2349888994603834 1.0 0.5561169082432014 14 P09601,Q13951 2 +Positive regulation of protein export from nucleus 0.6137493025170803 1.1822229836596954 0.237117235295639 1.0 0.5598946236561947 8 Q9Y3B8 1 +Cellular response to vascular endothelial growth factor stimulus 0.6559388105255883 1.181434709627127 0.2374300761887937 1.0 0.5599351794103363 6 P04792,P31749 2 +Phagocytosis 0.4269351840430855 1.1812859750138356 0.2374891369117644 1.0 0.5599351794103363 32 Q9NWH9,Q8WTV0 2 +Defense response to fungus 0.6717973838684486 1.1796183589282478 0.2381520377578625 1.0 0.5610424198599883 5 O95999,P81605 2 +Regulation of response to external stimulus 0.3400128237127494 1.1788516079521594 0.2384572700681797 1.0 0.5613792703991375 113 O75844,O95747,P80303,Q96ST3,Q9NZ08,Q9NWH9,Q8NE86,P04792,P33527,Q9NZM5,P49593,Q8N2K0 12 +Epithelial tube formation 0.4738668612047049 1.178319206931215 0.2386693734646083 1.0 0.5614599195437918 19 Q13043,O95747 2 +Regulation of protein binding 0.3935984937194977 1.1775159810358748 0.2389896227525394 1.0 0.561470141863775 42 Q8TEY7,P31749,Q7KZI7,Q9BUN8,Q13043,Q9UNE7 6 +Hormone transport 0.4477013890379224 1.1757987046565537 0.2396753241537192 1.0 0.5623597163532454 26 Q16822,Q8NE86 2 +Mitophagy 0.5382889623358179 1.1749926428844255 0.2399976592069852 1.0 0.5629068425828027 12 P53365,Q9Y4P1 2 +Regulation of response to oxidative stress 0.4731695364163951 1.174016169198364 0.2403885491971349 1.0 0.5636142961866728 19 P31749,P00374,Q9NWH9,P04792,P04179 5 +Cholesterol storage 0.807187025860046 1.1720788471789785 0.2411654015994975 1.0 0.5652258150331207 3 Q8WTV0 1 +Centromere complex assembly 0.6692650838032378 1.1694804623854076 0.242210108397904 1.0 0.5656829662608254 5 Q7Z7K6 1 +Modified amino acid transport 0.6530039766320457 1.169360215422108 0.2422585318545853 1.0 0.5656829662608254 6 O15439,P33527,Q9H2D1 3 +Histone h3 k4 demethylation 0.6581227436823066 1.1691402353364688 0.2423471354667163 1.0 0.5656829662608254 2 O60341 1 +Regulation of organ growth 0.5557782280374028 1.1672376706811178 0.243114401861078 1.0 0.5662207057730898 11 P80723,Q9UGN5,P31749 3 +Tube morphogenesis 0.3363357384103645 1.166959033924422 0.2432269136889522 1.0 0.5662738691121108 87 P20936,O95747,P31749,Q96PU8,P14923,Q9NZ08,P09601,Q9NWH9,P04792,Q96T37,P42785,O95470,Q9UII2,P42574,Q13043 15 +Protein n linked glycosylation 0.5171691523414494 1.1660855427295371 0.2435798612817197 1.0 0.5668865625259042 13 P04843,P46977,Q8TCJ2,P04844,Q9NYU2 5 +Negative regulation of peptidyl threonine phosphorylation 0.6566787003610071 1.1624858036964008 0.2450381879006149 1.0 0.5683949736974603 2 Q04637 1 +Response to epinephrine 0.6566787003610068 1.1624858036963992 0.2450381879006156 1.0 0.5683949736974603 2 P17612 1 +Cellular response to epinephrine stimulus 0.6566787003610068 1.1624858036963992 0.2450381879006156 1.0 0.5683949736974603 2 P17612 1 +Mammary gland epithelium development 0.6088575482601809 1.1606054254081322 0.2458023980715662 1.0 0.5694838941514958 8 P31749 1 +Negative regulation of regulated secretory pathway 0.7870123183942048 1.1594709308287097 0.246264278897283 1.0 0.5695749291885294 4 P04899 1 +Regulation of protein containing complex assembly 0.33869636165687 1.1589702875184509 0.2464682965111357 1.0 0.5695749291885294 96 Q9UQB8,P20936,Q6IBS0,P51608,Q9UBB9,Q9NWH9,Q9NWS0,P26038,Q9NZM5,P58546,O95429,Q71SY5,Q9UNE7,Q9NVN8 14 +Regulation of extent of cell growth 0.4638561289787197 1.1571011550103427 0.2472310348490434 1.0 0.5706311477955633 20 Q96ST3,Q9P265 2 +Export across plasma membrane 0.6075420140520186 1.1547938607257813 0.2481748517751012 1.0 0.5715898238900936 8 P33527 1 +Regulation of cell projection organization 0.3390168119221926 1.154616690757633 0.2482474286290388 1.0 0.5715898238900936 100 Q9H4M9,Q9UQB8,Q14195,Q6IBS0,P31749,Q7KZI7,Q9H2U1,Q12756,Q9Y639,P07196,Q9NQW6,Q08209,Q9P265,P20339,Q9Y3P9 15 +Transition metal ion homeostasis 0.4634482080235395 1.154526152876958 0.2482845227835759 1.0 0.5715898238900936 20 P30519,P09601,O75027 3 +Regulation of intracellular estrogen receptor signaling pathway 0.571681326563187 1.154447916256292 0.2483165801283697 1.0 0.5715898238900936 10 Q96HY6,Q969T9 2 +Polyol metabolic process 0.4547061151884448 1.1541920005922852 0.2484214614371049 1.0 0.5716228525925222 22 Q01968,P00374,P61457,Q16822,P51608 5 +Estrogen metabolic process 0.6651965042013386 1.1531981979073165 0.248829043034175 1.0 0.5717272844678972 5 O95470 1 +Regulation of hormone metabolic process 0.6486253777110489 1.1513528705556382 0.2495870944449489 1.0 0.5726355066589418 6 O75844 1 +Pigment metabolic process 0.4470297133494735 1.1504031960085397 0.2499778444099383 1.0 0.5729625261499417 25 Q9UII2,P30519,P33527,O75027 4 +Response to abiotic stimulus 0.3102016526713679 1.1503448566486183 0.2500018624553515 1.0 0.5729625261499417 189 O95202,O95747,Q9H2U1,P00846,P58546,O75844,Q9Y376,Q9Y639,Q13217,Q13432,Q8N2K0,Q96EY1,P31749,P31751,O75190,Q9NZM5,P14923,P30519,P09601,Q9BVC6,P46100,P42574,P51608,Q9UNE7 24 +Phosphatidylserine metabolic process 0.7839472631824161 1.1482511051493685 0.2508649175182924 1.0 0.5741069551324749 4 Q8NCC3 1 +Cellular response to biotic stimulus 0.4225965891989942 1.1479479495443996 0.2509900519493231 1.0 0.5741852130463863 32 O75844,Q86U42,P31749,O76024,Q96A33,Q8WTV0 6 +Protein catabolic process in the vacuole 0.6474793996189915 1.1466415433546535 0.2515297993922631 1.0 0.5750033140343047 6 O14773 1 +Regulation of glycolytic process 0.6264066291287078 1.145575039033114 0.2519710302143561 1.0 0.5751838649304989 7 O15294,P40763 2 +Endosomal vesicle fusion 0.6519855595667831 1.1408789787546982 0.2539202883385394 1.0 0.5785431923797721 2 Q9P2R3 1 +Ubiquitin independent protein catabolic process via the multivesicular body sorting pathway 0.6519855595667831 1.1408789787546982 0.2539202883385394 1.0 0.5785431923797721 2 Q8WUM4 1 +Phosphatidylglycerol metabolic process 0.5501691655479832 1.1395395081757291 0.2544781995524698 1.0 0.5790215279517861 11 O95674,Q8NCC3 2 +Memory 0.6455366858458456 1.1386563774205103 0.2548465039876486 1.0 0.5790215279517861 6 P51608,Q8NBU5 2 +Positive regulation of cell projection organization 0.3772846873759864 1.1380631828082617 0.2550941003093534 1.0 0.5791141085264382 57 Q9UQB8,Q6IBS0,Q14195,Q7KZI7,Q9H2U1,P07196,Q9Y639,Q9NQW6 8 +Extrinsic apoptotic signaling pathway via death domain receptors 0.492278810766862 1.1374604549236766 0.2553458470284453 1.0 0.5791141085264382 14 Q13043,P09601 2 +Antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii 0.6505415162454833 1.1342372895761543 0.2566950261461396 1.0 0.5811073759873043 2 P50570 1 +Protein insertion into er membrane by stop transfer membrane anchor sequence 0.643869107423682 1.1318039101961113 0.2577168834525118 1.0 0.5828167629366618 6 Q8N4V1 1 +Androgen metabolic process 0.7793250004067904 1.131344113139144 0.257910284111329 1.0 0.5830453039308741 4 O95470 1 +Regulation of release of cytochrome c from mitochondria 0.5294022806922393 1.129291975413269 0.2587746849348771 1.0 0.5839540245456805 12 O14737,P31749 2 +Positive regulation of membrane potential 0.658980917779136 1.1283409339142232 0.2591759623764809 1.0 0.5843482031957964 5 P31749 1 +Epidermis development 0.3877457281264638 1.1277478343856626 0.2594264297856676 1.0 0.5843482031957964 43 O75116,O75844,P51648,Q9Y3B8,Q01469,O14745,P42574,P18074,Q13043,Q9P0M6,P15924 11 +Amyloid beta clearance 0.6013489812371637 1.1274494194450155 0.2595525145297452 1.0 0.5843482031957964 8 Q16850 1 +Cellular component morphogenesis 0.3366448908398274 1.1205221021902982 0.2624913393968016 1.0 0.588973104815709 107 Q9UQB8,Q6IBS0,Q8TEY7,Q13596,Q7KZI7,Q9H2U1,Q96ST3,Q9Y639,P07196,Q04837,Q9Y5P4,Q08209,P35609,Q9P265 14 +Positive regulation of protein kinase activity 0.3856327774719347 1.120172459657924 0.2626402775186689 1.0 0.5890979439619451 46 O75832,O43318,P31749,Q7KZI7,Q13432,Q9Y376,Q9NWS0,Q96M27,P36507,Q9UER7,Q13043,P14635,P54619 13 +Cell differentiation involved in embryonic placenta development 0.7926374635304066 1.1187730384359695 0.2632369766789906 1.0 0.589807761089832 3 O75190 1 +Hepatocyte growth factor receptor signaling pathway 0.6565252978382761 1.1185271829695815 0.2633419035290381 1.0 0.5898335505081045 5 Q9NWH9 1 +Inositol phosphate catabolic process 0.7756507475092886 1.117916913002766 0.2636024808943213 1.0 0.5902078242435267 4 Q9NX62,Q01968 2 +Negative regulation of phosphatidylinositol 3 kinase signaling 0.6560453108252008 1.1166094339978323 0.2641613561566873 1.0 0.5905213360164318 5 O14745,Q9NZM5 2 +Histone serine phosphorylation 0.7918065786139514 1.1157345381829529 0.2645357819050178 1.0 0.5910399599958537 3 Q13043 1 +Regulation of tau protein kinase activity 0.6462093862815845 1.1143323058491743 0.265136652545562 1.0 0.5913182809628823 2 P08238 1 +Positive regulation of tau protein kinase activity 0.6462093862815845 1.1143323058491743 0.265136652545562 1.0 0.5913182809628823 2 P08238 1 +Pyridine nucleotide biosynthetic process 0.7912603828096696 1.113737498334821 0.2653918173471861 1.0 0.5913182809628823 3 P43490,Q9BQG2 2 +Regulation of histone h3 k14 acetylation 0.7906385428792471 1.111464242934897 0.2663685730084408 1.0 0.5926184531273063 3 Q03164 1 +Protein localization to endosome 0.5974793310106088 1.1103775518071946 0.266836367338839 1.0 0.5928236535458935 8 O75116,P26038,P35241,Q9UNF0 4 +L serine catabolic process 0.6451263537906096 1.1093610108724934 0.2672744749855842 1.0 0.5929624156918407 2 P34897 1 +Synapse assembly 0.5435424721839169 1.10684818580109 0.2683595709760507 1.0 0.5948626919215181 11 Q9Y639 1 +Regulation of fat cell differentiation 0.4830387123338697 1.1064697667437131 0.2685232428741839 1.0 0.5948626919215181 15 P31749,Q16539,Q8N4Q0,Q00839,P04179,Q13043 6 +Dna methylation on cytosine 0.6444043321299597 1.1060479637140932 0.2687057597723055 1.0 0.5948626919215181 2 Q96KQ7 1 +Response to sodium arsenite 0.7887275527642941 1.1044806954703108 0.2693846730926672 1.0 0.5959687546976528 3 P07196 1 +Positive regulation of heart growth 0.6529155335301815 1.104108878673527 0.2695459102666697 1.0 0.5961165945442216 5 P80723,Q9UGN5 2 +Actomyosin contractile ring organization 0.6526924466931489 1.103218143988682 0.2699324438256809 1.0 0.5963774450458994 5 Q9H0H5,Q8WUM4,Q15149,Q9NQW6 4 +Mononuclear cell migration 0.4469119179377759 1.103185823142122 0.2699464765740254 1.0 0.5963774450458994 22 P26038,Q5JRA6,O95747,P31749 4 +Lipoprotein metabolic process 0.4781338398379314 1.1009132991888952 0.2709343933332009 1.0 0.5975130141480373 16 Q8N2K0,Q92643,Q9NUJ1,Q8IUH4 4 +Regulation of fatty acid beta oxidation 0.7870642862209367 1.0984055122345169 0.2720274564682898 1.0 0.5990866271854839 3 P31749 1 +Alcohol metabolic process 0.343603326467564 1.0973700384851364 0.2724796653508905 1.0 0.5996489468450962 79 Q15392,P22570,Q01968,P51648,P00374,P61457,Q16822,Q15800,Q8WTV0,Q16850,P51608,Q9NX62 12 +Actin filament polymerization 0.3849692454756895 1.0973520591192285 0.2724875217845732 1.0 0.5996489468450962 38 Q9UQB8,Q6IBS0,P20936,Q12792,Q9NSV4,P58546,O95429 7 +Positive regulation of cell development 0.3766767009175741 1.0967340988686152 0.2727576457616592 1.0 0.5996489468450962 54 Q9UQB8,Q9Y639,Q8IZT6 3 +Peptidyl lysine modification 0.338181826064226 1.0954864725644144 0.2733035687121923 1.0 0.6000134676108423 82 O75844,Q9BU89,Q969T9,O43318,Q03164,O75448,P16403,P10412,Q96ST3,Q9NWS0,Q9BX68,P46379,P46100,P51608,Q9P265,Q9NVN8 16 +Developmental cell growth 0.411232598660546 1.0941031074175092 0.2739097597432416 1.0 0.6009303210184059 33 Q96ST3,Q9P265,Q9UGN5 3 +Neuroblast proliferation 0.5765743806157646 1.094099047726028 0.2739115400524188 1.0 0.6009303210184059 9 Q8IZT6 1 +Superoxide anion generation 0.7690392991174121 1.0937863125297194 0.2740487085622456 1.0 0.6010224195422087 4 P04899,Q9NY61 2 +Forelimb morphogenesis 0.7684866120188725 1.0917709991093392 0.2749337691388485 1.0 0.6017094690962528 4 O95747 1 +Lipid import into cell 0.6339321113344526 1.091011355484702 0.2752678859645487 1.0 0.6022319584130842 6 P31749 1 +Regulation of nuclear cell cycle dna replication 0.7847952580279339 1.0901225344186094 0.2756591710693832 1.0 0.6026703622341016 3 O75844 1 +Endosome transport via multivesicular body sorting pathway 0.6485386112083603 1.0866404214447052 0.2771957537402274 1.0 0.6049823674786713 5 Q8WUX9,Q92783 2 +Multivesicular body sorting pathway 0.6485386112083603 1.0866404214447052 0.2771957537402274 1.0 0.6049823674786713 5 Q8WUX9,Q92783 2 +Membrane protein ectodomain proteolysis 0.6122431817798817 1.0853413561482177 0.2777704955059534 1.0 0.6059673956066444 7 Q8TCT8 1 +Amyloid precursor protein catabolic process 0.475388634543644 1.0850714413802849 0.2778900148721872 1.0 0.6059673956066444 16 O75116,Q15392,Q92542,O95197,P42574,Q16799 6 +Regulation of t cell mediated immune response to tumor cell 0.639711191335736 1.0845366138559105 0.2781269421077059 1.0 0.6059673956066444 2 P09429 1 +Regulation of response to tumor cell 0.639711191335736 1.0845366138559105 0.2781269421077059 1.0 0.6059673956066444 2 P09429 1 +Mitotic dna replication 0.5206293915979046 1.0842471148038282 0.2782552467960424 1.0 0.6060378158917599 12 P18858 1 +Vesicle fusion to plasma membrane 0.7828511022378397 1.08303003624245 0.2787950912345101 1.0 0.6068633011743314 3 O95721 1 +Positive regulation of cytoskeleton organization 0.3829304329277159 1.082260777358616 0.2791366691043575 1.0 0.6071198514381376 42 Q9UQB8,P49593,Q9NWH9 3 +Axon extension 0.4414381585543014 1.0799034439964583 0.2801851794834546 1.0 0.6083525527023841 23 Q96ST3,Q9P265 2 +Regulation of cell projection size 0.7647559514191711 1.0781757469946314 0.2809553331264445 1.0 0.6090682607247456 4 P07196 1 +Regulation of mitochondrial dna replication 0.7815095702419661 1.078138504252459 0.280971950592902 1.0 0.6090682607247456 3 P49916,Q04837 2 +Regulation of multicellular organism growth 0.5555344149651774 1.0778509913639769 0.2811002594108633 1.0 0.6090682607247456 10 O75844,O95470 2 +Cardiac muscle cell cardiac muscle cell adhesion 0.7644900270915593 1.077207227689011 0.2813876970282285 1.0 0.6092873522072136 4 P14923,P78310 2 +Regulation of apoptotic process involved in development 0.6379061371841114 1.0762743876617975 0.2818045597633225 1.0 0.6099807988843395 2 Q07812 1 +Chondrocyte development 0.7807343880829067 1.07531297561995 0.2822346287850243 1.0 0.6102658678176097 3 Q8N5W9 1 +Negative regulation of response to reactive oxygen species 0.6454051702769972 1.0741452632391093 0.2827575805330777 1.0 0.6102658678176097 5 Q9NWH9,P32322 2 +Negative regulation of response to oxidative stress 0.6454051702769972 1.0741452632391093 0.2827575805330777 1.0 0.6102658678176097 5 Q9NWH9,P32322 2 +Optic nerve development 0.6361010830324869 1.0680188322376625 0.2855120169742489 1.0 0.6131710459780297 2 Q9H061 1 +Protein insertion into mitochondrial inner membrane 0.6280590370441551 1.066941407344271 0.2859982951635307 1.0 0.6140065405176922 6 Q9Y584,Q9Y5L4 2 +Regulation of synaptic plasticity 0.4412215486955163 1.0660134531911252 0.2864175604767378 1.0 0.6144887790860084 22 O95793,Q9UQB8,Q9Y639 3 +Mitochondrion morphogenesis 0.5349830374496958 1.064691886011765 0.2870153830862327 1.0 0.615144307130507 11 Q04837,Q9Y5P4 2 +Negative regulation of ion transport 0.4611815478920748 1.0641274782514203 0.2872709544377665 1.0 0.6154357546218356 18 P35609,O75915,O95747 3 +Regulation of supramolecular fiber organization 0.3291479317406364 1.0639611254012056 0.2873463105202996 1.0 0.6154357546218356 89 Q9UQB8,P53367,Q8NBJ5,P58546,P35609,Q6IBS0,Q12792,Q8WWK9,O95429,P20936,Q9NWH9,Q9BPX3,P53365,P49593,O15212,O75116,Q9Y624,P51608,P16949,P29372 20 +Negative regulation of transcription by rna polymerase i 0.7603287772215355 1.0620618042735868 0.2882076285250732 1.0 0.6156246059839525 4 Q9NZM5 1 +Microtubule organizing center localization 0.5162381457577461 1.0617362738687974 0.2883554270059323 1.0 0.6156246059839525 12 O43237,Q8IZT6 2 +Adult locomotory behavior 0.4976437979868712 1.0614476697224933 0.2884865028219083 1.0 0.6156246059839525 13 O75844,Q8N2K0 2 +Neuron fate commitment 0.6342960288808621 1.0597701835587323 0.2892491645855695 1.0 0.6156246059839525 2 Q96KQ7 1 +Pyridine containing compound metabolic process 0.568920400235197 1.059179404627705 0.2895180827515762 1.0 0.6156246059839525 9 P43490,O00764 2 +Leukocyte migration 0.380471624946939 1.0588710244269826 0.289658521983887 1.0 0.6156246059839525 41 O95747,P31749,P78310,P09601,Q8NE86 5 +Serine family amino acid biosynthetic process 0.6254136617206426 1.0561111814399662 0.2909174225303279 1.0 0.6172219777743584 6 Q9Y617,P00374,P34897 3 +Regulation of fatty acid oxidation 0.7586231791053766 1.055859800013895 0.2910322725822012 1.0 0.6172582361719914 4 P31749 1 +Dna strand elongation 0.4537965252645606 1.054698846718792 0.2915630794183341 1.0 0.6179688766187854 19 P18858 1 +Negative regulation of smooth muscle cell proliferation 0.6046534361266791 1.053139812722378 0.2922769183544074 1.0 0.6188586393325715 7 P09601,O95140 2 +Cellular response to arsenic containing substance 0.5843742263902522 1.052667677089624 0.2924933277150372 1.0 0.619109242773297 8 Q9H2U1,P09601 2 +Organic cation transport 0.6398929523711444 1.0521881807877138 0.2927132210433563 1.0 0.6191595570076219 5 Q70HW3 1 +Histone h4 acetylation 0.4591067560793975 1.051661802867393 0.2929547416962879 1.0 0.619462906587529 18 Q03164 1 +Long chain fatty acid transport 0.4957624009356231 1.0513919735034047 0.2930786007212485 1.0 0.6195173367773562 13 Q01469,P31751,P31749 3 +Striated muscle cell proliferation 0.6385977593060927 1.0470337676596726 0.2950840043913372 1.0 0.6216751430520198 5 Q16539,P52294,P10644,P06493 4 +Response to molecule of bacterial origin 0.3903441794598473 1.0451650016980687 0.2959467158412661 1.0 0.6226529953344945 36 Q86U42,P31749,Q02952,Q16822,Q8WTV0,P42574,P04179 7 +Response to salt 0.637969415775381 1.044533877355186 0.2962384539095377 1.0 0.6226529953344945 5 P07196 1 +Protein peptidyl prolyl isomerization 0.4358781566446275 1.0431428455945675 0.2968821395150727 1.0 0.6232703008680961 23 Q9Y237,O95302 2 +Vascular transport 0.5125877929130683 1.0430459798628042 0.2969269979428623 1.0 0.6232703008680961 12 Q01469,P33527 2 +Calcium mediated signaling 0.4717513320860328 1.0423773217364447 0.2972367765163697 1.0 0.6235059823668965 15 O75844 1 +Respiratory chain complex iii assembly 0.6371310616521763 1.0411991745973816 0.2977831187262945 1.0 0.6244074037695346 5 Q69YU5 1 +Amyloid precursor protein biosynthetic process 0.770314192849395 1.0374048474450228 0.2995472201582672 1.0 0.625356449655299 3 Q92542,Q9NY61 2 +Negative regulation of small gtpase mediated signal transduction 0.5114719196231862 1.037337062173825 0.29957879890526 1.0 0.625356449655299 12 O95140,P20936,Q9NWH9 3 +Spindle midzone assembly 0.6202433716801607 1.0349670045785255 0.3006843206637035 1.0 0.6269883753865998 6 Q02241,Q9H0H5,O43663 3 +Regulation of respiratory system process 0.7695235169452147 1.0345343477734297 0.3008864280118644 1.0 0.6271600871409752 3 P51608 1 +Response to hyperoxia 0.7524331265012374 1.0333812038318988 0.3014255391071994 1.0 0.6272909867906582 4 P00846 1 +Fibroblast proliferation 0.4694130284184661 1.029129769807029 0.3034186986692408 1.0 0.6305310077944486 15 O75844,Q71SY5,P14635 3 +Positive regulation of multicellular organismal process 0.3012669127377425 1.0281459183118329 0.303881193651965 1.0 0.6305310077944486 179 Q9UQB8,O95747,Q9H2U1,Q02952,P07196,Q08209,P58546,P04899,Q6IBS0,Q9Y639,P04792,Q9UGN5,Q9P0M6,O43318,Q8IZT6,P31749,P39019,Q9NZ08,Q01469,P40763,P23786,O00767,O95140,P07954,P14923,P09601,Q13951,P80723,O15294 29 +Regulation of guanyl nucleotide exchange factor activity 0.7508262724800917 1.0275541839330105 0.3041595852181584 1.0 0.6306794843388661 4 Q9NWH9 1 +Mesoderm morphogenesis 0.5978082910027199 1.0241567681445127 0.3057612346996019 1.0 0.6331834817623111 7 P17612,Q16881,Q96A65 3 +Water soluble vitamin metabolic process 0.4543854811696067 1.023331668249297 0.3061510554428204 1.0 0.6337828734642519 18 P00374,O00764,P33527 3 +Vascular associated smooth muscle cell apoptotic process 0.7495855192463345 1.0230571774214932 0.3062808123921821 1.0 0.6338436740230211 4 O95140 1 +Cilium organization 0.3734515920393079 1.0187935237350665 0.3083010009635527 1.0 0.6358880615720918 48 Q9H4M9,A6NIH7,Q14141,Q01968,A0AVF1,O14745,O15439,O95721,Q96A65,Q9Y3P9 10 +Metal ion homeostasis 0.3506793139101928 1.0186818019001571 0.3083540548222643 1.0 0.6358880615720918 68 Q8TAD4,O75027,P30519,Q9Y639,P09601,Q8NE86,Q96A33,P04899,Q8NE01 9 +Mast cell activation 0.7483735941132407 1.0186667207219564 0.3083612169529004 1.0 0.6358880615720918 4 P09601 1 +Mast cell activation involved in immune response 0.7483735941132407 1.0186667207219564 0.3083612169529004 1.0 0.6358880615720918 4 P09601 1 +Sensory organ morphogenesis 0.4351522605638326 1.016824893704304 0.309236737561517 1.0 0.6370377686666945 21 O95747,O95140,P40763 3 +Glycoprotein metabolic process 0.3753672874552738 1.0150441882019985 0.3100847642183302 1.0 0.63795216724488 42 P04843,P46977,Q9NY61,P62820,P35610,Q92542,Q8TCJ2,O60762,O60701,O60502,P04844,O15294,Q9NX62,Q9NYU2,Q9BS26 15 +Positive regulation of catalytic activity 0.3018927676579827 1.0142560054241652 0.3104606108828793 1.0 0.6381016592169597 185 O75832,Q86U42,Q7KZI7,Q969S3,P22033,Q8WTV0,P36507,P04899,Q9UER7,P14635,Q14997,O75915,Q9Y376,Q92542,Q96M27,Q96HY6,Q13432,P20936,O00487,O43318,P31749,Q15750,Q16539,Q16763,Q9NWH9,P31751,Q04837,Q15404,Q8IV63,P40763,P61088,Q00839,Q13043,P49593,Q9Y3P9,Q9BRX5,P00374,Q9NWS0,O14737,Q9UNE7,P54619 41 +Inclusion body assembly 0.5585844927371455 1.0121487964085347 0.3114669140951855 1.0 0.6391297028264549 9 O75190 1 +Cellular transition metal ion homeostasis 0.4574335589985522 1.009965105679432 0.3125120082826997 1.0 0.6403354186115464 17 P09601,O75027 2 +Positive regulation of kinase activity 0.3600643090871495 1.0075061146620634 0.3136916207847215 1.0 0.6405720872039884 60 O75832,O43318,P31749,Q7KZI7,Q969S3,Q9Y376,Q9NWH9,P36507,Q13432,Q13043,P14635 11 +Regulation of protein localization to endosome 0.7448820398462458 1.0060295854284549 0.3144013385638975 1.0 0.6408175471994911 4 O75116,P26038 2 +Positive regulation of protein localization to early endosome 0.7448820398462458 1.0060295854284549 0.3144013385638975 1.0 0.6408175471994911 4 O75116,P26038 2 +Sodium ion transport 0.4567191588013309 1.005778421377174 0.3145221696432418 1.0 0.6408175471994911 17 O95747 1 +Locomotion 0.3047523181496955 1.0049318244179068 0.3149296790116962 1.0 0.6408175471994911 206 Q8TEY7,O95747,Q7KZI7,P78310,P07196,Q08209,P33527,Q8WTV0,P04899,Q9Y639,Q9NQW6,Q8NE86,P04792,P26038,Q96HY6,O95429,Q5JRA6,Q96JJ3,Q96G23,Q8IZT6,P31749,P39019,Q7Z7K6,Q9NWH9,P31751,P42785,Q13043,P49593,Q14195,P14923,P09601,Q96RL7,P58107,O95470,O94901,P51608 36 +Positive regulation of toll like receptor 9 signaling pathway 0.622021660649815 1.0038815959180851 0.3154356884219225 1.0 0.6408175471994911 2 P09429 1 +Regulation of toll like receptor 9 signaling pathway 0.622021660649815 1.0038815959180851 0.3154356884219225 1.0 0.6408175471994911 2 P09429 1 +Toll like receptor 9 signaling pathway 0.622021660649815 1.0038815959180851 0.3154356884219225 1.0 0.6408175471994911 2 P09429 1 +Tail anchored membrane protein insertion into er membrane 0.5396698832299931 1.0029053179018177 0.3159065465486601 1.0 0.6412924799068056 10 Q8N4V1,P46379 2 +Positive regulation of lipid storage 0.7439210960551327 1.0025547534558157 0.3160757360579631 1.0 0.6412924799068056 4 Q8WTV0 1 +Protein localization to cell surface 0.4680485655379135 1.001950486870817 0.3163675069729279 1.0 0.6416782650263626 14 P35609,P31749 2 +Regulation of actin filament based process 0.3399090019757256 1.000867375681205 0.3168909308632617 1.0 0.6425335059314818 76 O75116,Q9UQB8,Q6IBS0,P20936,Q12792,P14923,P53367,P52565,Q9NWH9,P16949,Q9BPX3,Q9Y624,P58546,P35609,O95429,P53365,P49593,P15924 18 +Response to platelet derived growth factor 0.6263885325102705 0.998548959467248 0.3180132359946364 1.0 0.6446021098138472 5 P35241 1 +Regulation of glycoprotein metabolic process 0.5909616079862358 0.9952341594734276 0.3196223915505569 1.0 0.6464653961797868 7 P62820,P35610,Q92542,Q9NY61 4 +Neuron projection extension 0.4186120842699571 0.9951921087999775 0.3196428390266803 1.0 0.6464653961797868 27 Q96ST3,Q9P265 2 +Response to axon injury 0.484738720293146 0.9926117566826246 0.3208991931671099 1.0 0.6467148118918391 13 Q14195,P00374,Q96G23,P07196 4 +Histone h3 k9 modification 0.4845586344871657 0.991653758365298 0.3213664555576552 1.0 0.647243317509102 13 P51608,Q03164,P46100 3 +Cell morphogenesis involved in differentiation 0.3267374401425825 0.9873648071028324 0.3234638305583104 1.0 0.6499993464852049 104 Q9UQB8,Q6IBS0,Q8TEY7,Q7KZI7,Q9H2U1,Q96ST3,Q9Y639,Q9NWH9,P07196,Q08209,P42574,Q9P265 12 +Negative regulation of guanyl nucleotide exchange factor activity 0.7564396971460559 0.9871717812658984 0.3235584330064933 1.0 0.6499993464852049 3 Q9NWH9 1 +Platelet activation 0.5015866968025335 0.986869959116846 0.3237063929346844 1.0 0.6500897471340958 12 Q16539,P04792,Q9Y624,Q9BWH2 4 +Membrane protein intracellular domain proteolysis 0.7561808594097836 0.9862376026400322 0.3240165310545952 1.0 0.6504082360581538 3 Q8TCT8 1 +Negative regulation of dna binding 0.5887264754744712 0.9858085489905138 0.3242270698342164 1.0 0.6505146866645194 7 P09601 1 +Establishment of protein localization to membrane 0.3356721891056994 0.9854382672865256 0.3244088405289993 1.0 0.6506726236023195 78 Q4V328,Q9Y276,Q8NBU5,Q8N4V1,P31751,Q9Y5L4,P08240,Q15070,Q96A33,P46379,Q9NPA0,O14737,Q8IWJ2,Q9Y584,Q9NS69 15 +Lipoprotein biosynthetic process 0.5180296916234481 0.9815313961736514 0.326330759682943 1.0 0.6532823134553273 11 Q92643,Q8IUH4 2 +Regulation of trans synaptic signaling 0.3691081822498533 0.978898548861372 0.3276301092791742 1.0 0.6553952963237331 48 Q9UQB8,O95793,Q9Y639,Q01469,P04899 5 +Apoptotic signaling pathway 0.3155215402739055 0.9787618816140492 0.3276976481618665 1.0 0.6553952963237331 135 O75832,O75223,Q9NY61,Q969S3,P04899,O75915,P04792,Q9UGN5,P31749,O75489,O95470,Q9UII2,Q13043,P49593,P09601,Q9BVC6,P46379,P42574,O14737,Q9Y3B8 20 +Striated muscle cell differentiation 0.3711348708845453 0.976155480188302 0.3289874213815018 1.0 0.6571422267012978 40 O75844,P31749,P78310,Q08209,Q9UGN5,P58546,P35609,P42574 8 +Myeloid cell activation involved in immune response 0.5863001934504991 0.975586706390992 0.3292693148595522 1.0 0.6574972972875436 7 P09601 1 +Reactive oxygen species biosynthetic process 0.5503201691427273 0.9746741143626596 0.3297219371222124 1.0 0.658122925688019 9 O75027,Q15067 2 +Adult behavior 0.4513245035263192 0.9742107308986728 0.3299519176300158 1.0 0.658122925688019 17 O75844,P51608,Q92542,Q8N2K0 4 +Protein insertion into er membrane 0.4812567628805042 0.9741035247228524 0.3300051396089953 1.0 0.658122925688019 13 Q8N4V1,Q96A33,P46379 3 +Regulation of signal transduction by p53 class mediator 0.3998243276240091 0.9739048485071058 0.3301037861346145 1.0 0.658122925688019 32 O75844,P62841,P31749,Q9NZM5,Q9NWT1 5 +Microtubule depolymerization 0.4987743270183671 0.9725517067019362 0.3307761545542509 1.0 0.6592552524796529 12 Q8WWK9,Q99661,O00139,P16949,P29372 5 +Negative regulation of reactive oxygen species metabolic process 0.5496839619829548 0.9717947702817183 0.3311526581147346 1.0 0.6595892376455629 9 O75027 1 +Sperm capacitation 0.6148014440433169 0.9711925016760194 0.3314524271329435 1.0 0.6597700582967861 2 P17612 1 +Cd4 positive alpha beta t cell differentiation 0.6183655438156088 0.9668068991087184 0.3336405749070463 1.0 0.6624549025041166 5 Q13951 1 +Regulation of stress activated protein kinase signaling cascade 0.4172572930633425 0.9656386264526552 0.334225039968764 1.0 0.662931449970223 26 O75844,Q969S3,O75915 3 +Negative regulation of sister chromatid cohesion 0.7504254815809827 0.965496291476014 0.3342962925936072 1.0 0.662931449970223 3 Q7Z5K2 1 +Carbohydrate homeostasis 0.3698438941307356 0.9648844012706542 0.3346027152280477 1.0 0.6631141067011593 40 P31749,Q96ST3,Q16822,Q9NWS0,Q8NE86,Q08209,O76024,Q01469,P40763,P42785 10 +Regulation of endocytic recycling 0.733285200308871 0.9641926725597146 0.3349493373475956 1.0 0.663384603517164 4 P35609,Q4V328 2 +Regulation of actin filament length 0.3694488266788916 0.961437786528164 0.3363320926644904 1.0 0.6652884815424789 40 Q9UQB8,Q6IBS0,P20936,P58546,P35609 5 +Positive regulation of cold induced thermogenesis 0.4785685828579458 0.9598368766833288 0.3371373194809464 1.0 0.665899652226284 13 P07954,Q01469,P23786,O00767,O95140 5 +Histone h3 k27 trimethylation 0.7486978626677223 0.9592820977709714 0.3374166515036592 1.0 0.665899652226284 3 P16403 1 +Response to estrogen 0.530353229707575 0.9591055488699414 0.3375055753326783 1.0 0.665899652226284 10 Q969T9 1 +Negative regulation of protein secretion 0.5822470784236211 0.9585353270715486 0.3377928864713055 1.0 0.665899652226284 7 Q16850 1 +Behavior 0.3506976002588241 0.9585304280919292 0.3377953555447366 1.0 0.665899652226284 63 O75844,O75915,Q8NBU5,P31749,Q9Y639,Q92542,P04179,Q96RL7,O76024,P40763,P42574,P51608,Q8N2K0 13 +Glial cell apoptotic process 0.7480082191591778 0.9568030504957272 0.3386666722678779 1.0 0.6661499590963804 3 P42574 1 +Regulation of protein kinase activity 0.3196712268212353 0.9551411731217294 0.3395063099673709 1.0 0.6671779773215002 87 O75832,O43318,P31749,Q7KZI7,Q9Y3B8,Q9Y376,Q9NWS0,Q9UER7,P04792,Q99640,O14745,P36507,P42574,Q13432,Q13043,P49593,P14635 17 +Histone h2a phosphorylation 0.7293503211421074 0.9500491790785688 0.3420872644201056 1.0 0.6708061759508064 4 O75844 1 +Tissue morphogenesis 0.3569083076539724 0.9494553941641914 0.3423890482903506 1.0 0.6708913574149192 58 O95747,Q9NWH9,P26038,Q13043,Q96T37,P42574,Q96A65 7 +Cell projection assembly 0.3183688938260159 0.9450726680006794 0.3446217780300782 1.0 0.6736662249170011 86 Q9H4M9,A6NIH7,Q14195,Q6IBS0,Q01968,A0AVF1,Q14141,O95429,P57076,Q9NQW6,P20339,O14745,P53365,O15439,O95721,Q96A65,P35609,Q9Y3P9 18 +Muscle hypertrophy 0.4577538207926852 0.944770062973548 0.3447762787672723 1.0 0.6737056693178373 14 Q12792,Q08209,Q9UGN5,P58546 4 +Negative regulation of cell differentiation 0.3437748403805297 0.9446152141412316 0.3448553568633592 1.0 0.6737056693178373 68 O95747,Q14004,Q04917,P62805,Q8IZT6,Q96G23,P04179,Q13951,Q8N4Q0,Q08209,Q9H7N4,Q96T37,P40763,P51608,Q9P265,Q8N5W9 16 +Peptide antigen assembly with mhc protein complex 0.6086642599277934 0.94353160421611 0.3454090577419781 1.0 0.6741818217858848 2 P27797 1 +Regulation of oxidative stress induced cell death 0.45012873083165 0.9400742629841649 0.3471794693594705 1.0 0.6762257979364769 16 P04792,P04179,Q9NWH9,P31749 4 +Positive regulation of mirna mediated gene silencing by inhibition of translation 0.7424164186313729 0.9367367734768812 0.3488939753954376 1.0 0.6771011866731773 3 P40763 1 +Hydrogen peroxide biosynthetic process 0.7423848294081282 0.9366235939268854 0.3489522111356771 1.0 0.6771011866731773 3 Q15067 1 +Formation of primary germ layer 0.4916589409999266 0.9364188877623496 0.3490575569319594 1.0 0.6771011866731773 12 P17612,Q16881,Q96A65 3 +Positive regulation of canonical wnt signaling pathway 0.4740591353072086 0.935952141965614 0.3492978289678006 1.0 0.6771011866731773 13 Q8IZT6 1 +Cell division 0.2943254921933143 0.9334718870373132 0.3505763790511635 1.0 0.678375500254075 173 Q02241,Q9NY61,Q53EZ4,P04899,P14635,P18858,Q14141,Q8WWK9,Q99661,Q9NQW6,Q9BZD4,Q2NKX8,Q13432,P18074,Q9NTI5,Q9HBM1,P20936,Q8IZT6,P50748,O43768,Q7Z7K6,Q16763,Q9H0H5,Q99986,Q9BPX3,Q00839,O43663,Q8WUX9,P42695,O75116,Q7Z5K2,O43633,O00139,Q9Y3B8,Q86XL3,P16949,P18583 37 +Regulation of metal ion transport 0.3644945722470489 0.9320985404593718 0.3512856022659383 1.0 0.6795396117362544 47 P35609,P04899,O95747,P31749 4 +Positive regulation of vascular associated smooth muscle cell proliferation 0.7240907541502506 0.9311894744424752 0.3517555615596777 1.0 0.6798238799166835 4 P04899 1 +Muscle system process 0.3638158988259386 0.9305044011519048 0.3521099864540624 1.0 0.6801773410604905 48 P14923,P09601,Q9Y5P4,Q08209,Q9UGN5,P35609,P15924 7 +Cell death in response to hydrogen peroxide 0.5941208599683264 0.9287442010686008 0.3530216679794624 1.0 0.6812282431608576 6 Q9NWH9,P32322 2 +Positive regulation of microtubule polymerization or depolymerization 0.4725479592702006 0.927962386349646 0.3534270810623523 1.0 0.681342329118443 13 Q9NWH9 1 +Cell fate determination 0.6050541516245441 0.9273189476382472 0.3537609594511699 1.0 0.681342329118443 2 P60953 1 +Regulation of core promoter binding 0.6050541516245441 0.9273189476382472 0.3537609594511699 1.0 0.681342329118443 2 Q12948 1 +Regulation of morphogenesis of an epithelium 0.6050541516245442 0.9273189476382468 0.3537609594511701 1.0 0.681342329118443 2 Q99623 1 +Regulation of osteoclast differentiation 0.605054151624544 0.9273189476382454 0.3537609594511708 1.0 0.681342329118443 2 P42345 1 +Cytokine mediated signaling pathway 0.3652984817612603 0.9254304034251836 0.354742070016683 1.0 0.6826703535767561 41 O95747,Q96T37,Q8TCT8,P31749 4 +Phosphatidylinositol phosphate biosynthetic process 0.6077720538375966 0.9250695523768726 0.3549297297043305 1.0 0.682823373965004 5 Q01968 1 +Myotube cell development 0.7221166501271611 0.9241247780905166 0.3554213539672743 1.0 0.6833145281274519 4 Q08209 1 +Positive regulation of interleukin 8 production 0.5740426748979354 0.9241216764330188 0.3554229686579773 1.0 0.6833145281274519 7 O95999,P62820,P40763 3 +Homotypic cell cell adhesion 0.4506822217064482 0.9235394705816692 0.355726140949467 1.0 0.6833145281274519 15 P04792,P14923,P78310 3 +Protein processing involved in protein targeting to mitochondrion 0.73826869982623 0.9218940135946954 0.3565838620300889 1.0 0.6843375394705111 3 Q99797 1 +Positive regulation of interleukin 1 beta production 0.7380492353485943 0.9211096754635004 0.3569931692552868 1.0 0.6849148801816715 3 P04792 1 +Regulation of synapse structure or activity 0.4077361341481466 0.9195842038964016 0.3577900844387669 1.0 0.6854024857847009 27 Q9H2U1,Q9UQB8,Q4V328 3 +Negative regulation of release of cytochrome c from mitochondria 0.5909992815123573 0.9161355817057096 0.3595957873927209 1.0 0.6870634527350722 6 P31749 1 +Negative regulation of receptor signaling pathway via stat 0.6025270758122698 0.915997468006134 0.3596682229255656 1.0 0.6870634527350722 2 O14964 1 +Negative regulation of receptor signaling pathway via jak stat 0.6025270758122698 0.915997468006134 0.3596682229255656 1.0 0.6870634527350722 2 O14964 1 +Cell cycle dna replication 0.4310704569874959 0.9158505383416794 0.3597452921669541 1.0 0.6870634527350722 19 P18858,O75844,P46100 3 +Cognition 0.4097298072472318 0.91420910567674 0.3606069804262977 1.0 0.6882697227192393 26 Q96P11,O75915,Q8NBU5,Q9Y639,P42574,P51608 6 +Embryonic cleavage 0.6047481882313658 0.913197060989732 0.3611389094062267 1.0 0.6886800608427818 5 Q9NY61 1 +Transcription initiation from rna polymerase ii promoter 0.4520126703104871 0.913030358272366 0.3612265752550421 1.0 0.6886800608427818 14 Q9H2U1,P62333,O75448,Q14241 4 +Smooth muscle cell proliferation 0.4188601802406092 0.912628523578562 0.3614379474732621 1.0 0.6886800608427818 21 P04899,P31749 2 +Regulation of pigmentation 0.6010830324909702 0.9095385533025288 0.3630659168290893 1.0 0.6904813851984547 2 Q07812 1 +Polyol biosynthetic process 0.4861559442812491 0.9085767870331348 0.3635735642608988 1.0 0.6911913199682084 12 P00374,Q16822 2 +Neuromuscular process 0.4164919576928068 0.9055947333065896 0.3651503974526076 1.0 0.6934707104523311 22 O75844,P07196,O14773 3 +Regulation of microvillus length 0.7336825332859882 0.9055257886297832 0.3651869040630346 1.0 0.6934707104523311 3 Q6IBS0 1 +Morphogenesis of embryonic epithelium 0.4174440996264834 0.9036251602446588 0.366194195301641 1.0 0.6947482614289444 21 Q13043,O95747 2 +Inositol phosphate metabolic process 0.6022323423281024 0.9033344180047028 0.3663484350012531 1.0 0.6947482614289444 5 Q9NX62,Q01968 2 +Mitochondrial electron transport cytochrome c to oxygen 0.6022028015083369 0.9032186964008244 0.3664098369588826 1.0 0.6947482614289444 5 P13073,P15954,P00403 3 +Membrane protein proteolysis 0.533513973369293 0.8989306905419805 0.3686895794446971 1.0 0.6964534298041748 9 Q8TCT8 1 +Regulation of actin filament organization 0.3477854504120389 0.8984162290867619 0.3689636874714863 1.0 0.6964534298041748 61 O75116,Q9UQB8,Q6IBS0,P20936,Q12792,P53367,Q9NWH9,P16949,Q9BPX3,P58546,P35609,O95429,P53365,P49593 14 +Mitotic metaphase plate congression 0.4091697840097176 0.8938838073862398 0.3713840623571223 1.0 0.6992669024905354 25 Q8WUX9,Q53HL2,Q53EZ4,Q99661,Q9BZD4,Q00839,P14635 7 +Cellular response to nitrogen compound 0.316900993387019 0.8937152412047824 0.3714742685690679 1.0 0.6992669024905354 122 Q9UQB8,P43490,P31749,P14923,Q96ST3,Q16822,P31751,P33527,P46100,P35609,P04899 11 +Mitochondrial cytochrome c oxidase assembly 0.5850102623198762 0.8920067986213335 0.3723892883530064 1.0 0.7003589747521858 6 Q15070,Q9Y276 2 +Respiratory chain complex iv assembly 0.5850102623198762 0.8920067986213335 0.3723892883530064 1.0 0.7003589747521858 6 Q15070,Q9Y276 2 +Regulation of protein polymerization 0.3542308653495839 0.8910525289980219 0.3729009903018538 1.0 0.7006071547879624 55 Q9UQB8,Q6IBS0,P20936,Q12792,Q9NWH9,P58546,O95429,P51608,P16949 9 +Cytoskeleton dependent cytokinesis 0.3613384159337937 0.8909805551549499 0.372939602033947 1.0 0.7006071547879624 40 Q8WUX9,Q02241,P20936,O75116,Q14141,O43633,Q53EZ4,Q8WWK9,Q9NQW6,Q9H0H5,Q13432,P16949,P18583 13 +Vasculature development 0.3229135575129182 0.8906755114369324 0.3731032760034316 1.0 0.700636482042846 81 P20936,O95747,P31749,Q96PU8,P14923,Q9NZ08,P09601,P04792,Q96T37,P42785,O95470,Q9UII2,Q13043 13 +Vitamin metabolic process 0.4102021800366466 0.8866385500735166 0.3752735319679854 1.0 0.7041536644415631 24 P09455,P33527 2 +Positive regulation of phospholipase activity 0.597397903866992 0.8844233969501926 0.3764676974284571 1.0 0.7049279482690622 5 P35232,Q99623,P40616,P18085 4 +Tetrapyrrole biosynthetic process 0.4979015689977681 0.883672207323415 0.3768731875462836 1.0 0.7054780036072442 11 Q9UII2,Q9NRK6,O75027 3 +Branching morphogenesis of an epithelial tube 0.5299037523037833 0.8827579524648757 0.3773670631011714 1.0 0.7056055287960125 9 Q96T37,Q9NWH9 2 +Positive regulation of phagocytosis 0.5968416806628435 0.8822512022097404 0.3776409786298282 1.0 0.7056055287960125 5 P27797,P50570,Q08722 3 +Cellular response to molecule of bacterial origin 0.4049568634347119 0.881765775896453 0.377903482718843 1.0 0.7056055287960125 26 Q8WTV0 1 +Positive regulation of developmental growth 0.4125891371058547 0.8805182277479999 0.3785786351180578 1.0 0.7061581985629001 22 P80723,Q9UGN5,P31749 3 +Regulation of reactive oxygen species metabolic process 0.407075217008975 0.8798767097112419 0.378926102971175 1.0 0.706597582445363 25 O75027,P04899,Q9NY61,P42785 4 +Negative regulation of rho protein signal transduction 0.5810827569709612 0.8762309543749084 0.3809044918657269 1.0 0.7090303542571343 6 Q9NWH9 1 +Regulation of protein modification process 0.2958548536266329 0.8751806266809596 0.3814756326889128 1.0 0.7098842159734146 261 O75832,Q03164,Q7KZI7,P36507,P04899,Q9P265,Q9UER7,P14635,O75844,Q969T9,P62841,Q96ST3,Q9Y376,Q9Y639,P04792,Q13217,Q96HY6,O95429,Q13432,O43318,P31749,Q9UHR5,O43768,Q16763,P31751,Q9BX68,Q99640,Q9BUN8,Q9NZM5,P61088,Q13043,P49593,Q9NVN8,Q9NWS0,O14745,O15294,P46100,P42574,Q04323,P51608,Q9Y3B8,Q9UNE7 42 +Late endosome to vacuole transport via multivesicular body sorting pathway 0.7242995194088027 0.8721905328492195 0.3831044433322306 1.0 0.7117244038986937 3 Q92783 1 +Neuron migration 0.4112445565144849 0.8718987056972748 0.3832636398530638 1.0 0.7117431241271308 22 Q7KZI7 1 +Toxin metabolic process 0.5924187725631721 0.8709553999889638 0.3837785057648428 1.0 0.7122802720162309 2 P40616 1 +Mitochondrial protein processing 0.5785576913462899 0.8661095405371785 0.3864300937496927 1.0 0.7160577498735217 6 Q96TA2,Q10713,Q99797 3 +Endosome to lysosome transport 0.4941941129861402 0.8657857293419887 0.3866076764838193 1.0 0.7160577498735217 11 Q9P253,P20645 2 +Macroautophagy 0.3138592214774354 0.8652337275162828 0.386910517040937 1.0 0.7164085057467673 85 Q8WUX9,P21281,O95140,O43318,P31749,P42574,P09601,P20339,P60520,P53365,Q96HY6,O95721,Q92783,Q96A65,Q9Y4P1 15 +Response to lead ion 0.7220075969196844 0.8640812403224262 0.3875432636335256 1.0 0.7172314961749969 3 P36551 1 +Atp biosynthetic process 0.4111504336446301 0.8637376085788272 0.3877320487598321 1.0 0.7172314961749969 21 P00846 1 +Regulation of action potential 0.5409573152950473 0.8635335217872812 0.3878441969142334 1.0 0.7172314961749969 8 P14923,P78310 2 +Renal system process 0.5255684561151759 0.8633902133988826 0.3879229584158401 1.0 0.7172314961749969 9 P04899,O14745 2 +Hepaticobiliary system development 0.3945231732987349 0.8631527441641138 0.3880534916550586 1.0 0.7172628062968502 29 O75844,Q16822,P09601,Q9NWH9 4 +Regulation of cation transmembrane transport 0.3580847808447896 0.8626770137468038 0.3883150739518275 1.0 0.7175362531260869 41 P35609,Q8TAD4,O95747 3 +Trna aminoacylation for mitochondrial protein translation 0.5592441268183237 0.8624556159489993 0.3884368470420363 1.0 0.7175512733245808 7 Q9Y2Z4,Q5JPH6,Q5JTZ9 3 +Positive regulation of cytoplasmic translation 0.4934265616652628 0.8620889932937931 0.3886385477618965 1.0 0.7177138901926338 11 Q9H2U1,Q9H074,P11940 3 +Negative regulation of intracellular estrogen receptor signaling pathway 0.7041184971098249 0.8601080553324691 0.3897294812285568 1.0 0.718537610683728 4 A5YKK6,Q99623,Q9P253 3 +Cardiac muscle tissue development 0.4039853436101631 0.8592651020125075 0.3901942730993106 1.0 0.7191146060563478 25 P35609,O75844,P78310,Q9UGN5 4 +Negative regulation of oxidative stress induced cell death 0.476062258626046 0.8577825295370588 0.3910125584122745 1.0 0.7202022444034719 12 P04792,P04179,Q9NWH9,P31749 4 +Negative regulation of leukocyte migration 0.5902333304988155 0.8565042403911814 0.3917189283533944 1.0 0.720764937032714 5 P09601,P31749 2 +Synaptic signaling 0.3283908715921939 0.8556618649090036 0.3921848397120753 1.0 0.7210909093361321 75 Q9UQB8,Q8NBU5,Q02952,Q08209,P04899,P52294,P57105,O95793,Q9P253,Q9Y639,Q92542,Q99808,Q13432,Q96A65,P35268,P31749,Q01469,O95721,P20339,P56545,O00161,P51608 22 +Programmed cell death 0.2699886094299486 0.8550510648948111 0.3925228785854111 1.0 0.7210909093361321 377 O75832,O75223,O95747,Q03164,Q9NY61,Q969S3,Q02952,P07196,Q9NVI7,Q86XP3,P52565,O95197,P35609,P04899,Q14728,Q9UER7,Q9NS69,O75844,Q15392,O75915,Q96ST3,Q8WWK9,P04792,Q13217,Q9UGN5,Q96TA2,Q96HY6,O95429,Q96EY1,P20936,Q96JJ3,O43318,P31749,O75489,Q9NWH9,P31751,O75190,Q9BX68,Q96KA5,Q9NZM5,Q9UDX5,Q9UII2,P42574,Q13043,P49593,O95140,Q04760,P13051,Q9Y3A2,P09601,Q9NWS0,Q9Y3E5,P04179,Q9BVC6,O14745,O15294,P46379,O95470,O14737,P51608,Q9Y3B8 61 +Supramolecular fiber organization 0.2854775789232521 0.852929969126335 0.3936981410797835 1.0 0.7223902090103724 160 Q9UQB8,P04350,P60983,P84095,Q07157,P29372,P07196,P53367,Q15942,Q68EM7,Q8NBJ5,Q9UHD1,P35609,P58546,P52306,P10644,Q8N5W9,Q6IBS0,O15145,Q12792,Q8WWK9,Q99661,P35241,Q8NE86,Q14651,O95429,Q99471,Q6WCQ1,P20936,Q96JJ3,Q9UHB6,Q08722,Q9NWH9,O75190,Q92974,Q9BPX3,P53365,P49593,O15212,O75116,P07197,Q14195,Q15149,Q9NSV4,Q96S59,Q9BSJ2,O60610,Q96CW5,P58107,Q9Y624,O00139,P51608,P16949,P15924 54 +Response to wounding 0.3370931508996055 0.8517513073534557 0.3943521371436178 1.0 0.7225616281577133 65 Q8WUX9,Q14195,P42574,P00374,P07196,P09601,Q08209,P04792,P58107,Q8WTV0,P42785,Q5JRA6,Q9BWH2,P15924 14 +Exit from mitosis 0.4912772009499715 0.8517490316555723 0.3943534004801203 1.0 0.7225616281577133 11 Q8WUX9,P50748,Q9NQW6,Q16763 4 +Transepithelial transport 0.5746527717967296 0.8504915236575954 0.3950518710383752 1.0 0.7232118045045814 6 P33527 1 +Activated t cell proliferation 0.5882031590648028 0.8486178073867026 0.3960939949060673 1.0 0.7238768295923234 5 P10644,P42574 2 +Negative regulation of fibroblast proliferation 0.573670615195766 0.846570130335908 0.3972347687411595 1.0 0.7246132885641691 6 Q71SY5 1 +Muscle cell development 0.39693939861834 0.8452212088806695 0.3979873428790894 1.0 0.7246132885641691 27 P35609,O75844,P78310,Q9UGN5 4 +Cellular response to gamma radiation 0.5210105606714535 0.8430951465708432 0.3991752329297231 1.0 0.7257104580242648 9 O75844 1 +Anterior posterior axis specification 0.5865216161578488 0.8420943928764257 0.3997351195793071 1.0 0.7261011349320324 5 Q9Y2W6 1 +Embryonic pattern specification 0.5865216161578488 0.8420943928764257 0.3997351195793071 1.0 0.7261011349320324 5 Q9Y2W6 1 +Embryonic axis specification 0.5865216161578488 0.8420943928764257 0.3997351195793071 1.0 0.7261011349320324 5 Q9Y2W6 1 +Peptide catabolic process 0.4890700265035193 0.8411498347370251 0.4002639998030521 1.0 0.7266437305222746 11 O14773 1 +Regulation of gene silencing by rna 0.4280031548545469 0.8390084868437302 0.4014645471561411 1.0 0.7281951021958848 17 O75844,P40763,Q08209,P36507 4 +Oocyte differentiation 0.5349714647224562 0.8378334247233479 0.4021242635750113 1.0 0.7291822516406149 8 Q9Y2W6 1 +Regulation of carbohydrate metabolic process 0.3850001889413582 0.8368618741190694 0.4026702130576782 1.0 0.7295436801280288 31 O75844,P31749,P31751,P40763,O15294,Q13043 6 +Protein tetramerization 0.3982334536231053 0.8363226209533358 0.4029734305987626 1.0 0.7298836032130199 26 Q99797,Q04837,Q15070,P31350,P04179,Q13043,Q9NPJ3,Q16630 8 +Cellular response to hormone stimulus 0.3148548166378335 0.8358760677285482 0.4032246272706663 1.0 0.7301291358150236 114 Q9UQB8,Q969T9,Q96HY6,O15173,P31749,Q16822,P31751,P42785,P35609,P04899 10 +Leukocyte chemotaxis 0.4039586088310359 0.834403014648587 0.4040539190382506 1.0 0.7311046802927302 23 O95747,Q8NE86 2 +Response to hormone 0.2843943665554857 0.8343138319575802 0.4041041593954368 1.0 0.7311046802927302 160 Q9UQB8,Q15392,Q969T9,Q96HY6,P43490,O15173,P31749,P61353,Q9Y376,Q16822,P09601,P07196,P31751,P42785,P35609,P04899 16 +Regulation of regulated secretory pathway 0.4345879789149014 0.8338578852254438 0.4043610717572621 1.0 0.7311385472724379 15 P04899,P20339 2 +Regulation of myotube differentiation 0.5843355273818729 0.8336257876380758 0.4044918893381166 1.0 0.7311656997654934 5 Q16539 1 +Chromosome organization involved in meiotic cell cycle 0.4269613972374748 0.833029824812843 0.404827908879741 1.0 0.7313640685243024 17 P42695,P46379,P46100 3 +Positive regulation of wnt signaling pathway 0.431225684608288 0.8330202758651304 0.4048332941863219 1.0 0.7313640685243024 16 Q9NVX2,P14923,Q8IZT6 3 +Keratinocyte development 0.6954479768785986 0.8295518627881255 0.4067922026088162 1.0 0.7329807107982746 4 Q9Y3B8,Q15149,Q8WX93 3 +Response to mitochondrial depolarisation 0.5693568277841783 0.8293806649405071 0.4068890388577688 1.0 0.7329807107982746 6 Q9UII2 1 +Regulation of autophagy of mitochondrion in response to mitochondrial depolarization 0.5693568277841783 0.8293806649405071 0.4068890388577688 1.0 0.7329807107982746 6 Q9UII2 1 +Regulation of early endosome to late endosome transport 0.517695801242284 0.8283816360365251 0.4074544031931273 1.0 0.7331013332902376 9 P26038,P35241,P36507 3 +Regulation of myoblast differentiation 0.7118449023014634 0.828294259609529 0.4075038729891329 1.0 0.7331013332902376 3 Q9H7N4 1 +Positive regulation of protein modification by small protein conjugation or removal 0.3766539895603829 0.8271361237235535 0.408159911443803 1.0 0.7338045788314842 33 O75832,Q16763,Q9BUN8,Q9NZM5,P61088,Q9UNE7 6 +Intracellular estrogen receptor signaling pathway 0.4332373344528823 0.8263891058857049 0.4085834012712217 1.0 0.7343568447556202 15 Q96HY6,Q969T9 2 +Regulation of mirna transcription 0.5685003500290781 0.8259745641314039 0.4088185208278716 1.0 0.7345703302524705 6 Q96KM6 1 +Regulation of cellular component movement 0.3094462736872378 0.8254937497699858 0.4090913297000056 1.0 0.7346423935511478 128 O95747,Q02952,Q08209,Q8WTV0,P04899,P57105,Q13630,Q8NE86,P04792,P26038,Q96HY6,O95429,Q5JRA6,Q96G23,P31749,P39019,Q9NWH9,P31751,P40763,P42785,Q13043,P49593,Q14195,P14923,P09601,P04179,O14745,P58107,O00139,P51608,P16949,P15924 32 +Regulation of establishment of protein localization 0.3141555728945368 0.8244936707228502 0.4096591106233971 1.0 0.7348260296807186 113 Q4V328,Q9C0E2,Q9Y282,P14923,O43768,Q8IWJ2,Q16822,P31751,Q8NE86,Q08209,Q16850,Q9UII2,Q9Y3B8,O14737,P49593 15 +Regulation of histone modification 0.3503377305469503 0.8237594612713102 0.4100762459469167 1.0 0.735177045054727 51 O75844,Q969T9,Q03164,Q9UHR5,Q96ST3,Q9NWS0,P46100,P61088,P51608 9 +Meiotic cell cycle process 0.3671631374429512 0.8174953166928685 0.4136454245884322 1.0 0.7396801838062288 35 P42695,Q8IZT6,Q9Y2W6,P46379,P46100,O94901 6 +Heart morphogenesis 0.4094385234398013 0.8173666740362684 0.4137189146652398 1.0 0.7396801838062288 20 Q9Y5P4,Q96T37,O75844 3 +Lymphocyte apoptotic process 0.4315746193280515 0.8172085076826009 0.4138092814246721 1.0 0.7396801838062288 15 Q96EY1 1 +Protein polyufmylation 0.708623461955499 0.8170117926113035 0.4139216889055694 1.0 0.7396801838062288 3 Q96HY6 1 +Alcohol catabolic process 0.4834957347811249 0.8144715363459164 0.415374871862944 1.0 0.7402331611671787 11 Q01968,Q8WTV0 2 +Actin filament organization 0.3127788890061481 0.8142634882620379 0.4154940215586511 1.0 0.7402331611671787 99 Q9UQB8,P60983,P84095,Q07157,P53367,Q15942,Q68EM7,P58546,P35609,Q8N5W9,Q6IBS0,O15145,Q12792,P35241,Q8NE86,Q14651,O95429,Q6WCQ1,P20936,Q96JJ3,Q9UHB6,Q08722,Q9NWH9,Q92974,Q9BPX3,P53365,P49593,O75116,Q14195,Q15149,Q9NSV4,O60610,Q9Y624,P16949 34 +Regulation of respiratory gaseous exchange 0.6909816575306287 0.8138927619726036 0.4157063875317441 1.0 0.7402331611671787 4 P51608 1 +Negative regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway 0.7076499213467387 0.8136082852472153 0.4158693899652648 1.0 0.7402331611671787 3 Q9NWS0 1 +Triglyceride metabolic process 0.547375602629393 0.8134568614192875 0.4159561697531122 1.0 0.7402331611671787 7 Q16822 1 +Actin polymerization or depolymerization 0.3520124510540734 0.8123272875970583 0.4166038567557379 1.0 0.7411153513725393 44 Q9UQB8,Q6IBS0,P20936,Q12792,Q9NSV4,P58546,P35609,O95429 8 +Positive regulation of stem cell differentiation 0.5787836268562073 0.8121829728731943 0.4166866483010001 1.0 0.7411153513725393 5 Q9H2U1 1 +Hippo signaling 0.5786976600813429 0.8118517012087866 0.4168767314010293 1.0 0.7412446302636155 5 Q16539,Q13043 2 +Sterol biosynthetic process 0.4002093039261115 0.8102612274767387 0.4177900543241759 1.0 0.7421949168054889 23 Q16850,Q15392 2 +Regulation of microvillus organization 0.6898199652022191 0.8098293105256834 0.4180382842166601 1.0 0.7422025130375942 4 Q6IBS0 1 +Biological adhesion 0.2933996729287667 0.8096858756189795 0.418120737864226 1.0 0.7422025130375942 148 Q9UQB8,Q9NY61,P78310,Q08209,Q8WTV0,P35609,Q9Y639,P04792,P26038,O95429,Q5JRA6,Q96EY1,P20936,Q96JJ3,P31749,O75190,Q13043,P49593,P14923,Q13951,P42574,P15924 22 +Regulation of bicellular tight junction assembly 0.5780787150604999 0.8094673029833896 0.4182464028983097 1.0 0.7422169162169554 5 O75116,P17612,Q9Y624 3 +Development of secondary sexual characteristics 0.7056699169375223 0.8066951362089981 0.4198421470032953 1.0 0.7437553515354072 3 Q99623,Q9H1B7 2 +Amyloid fibril formation 0.5632473664962119 0.8051356333564262 0.4207414150700845 1.0 0.7447606657562416 6 Q99471,O15212,P61758 3 +Detection of stimulus 0.4813415953764753 0.8041986074550543 0.4212822829161471 1.0 0.7455090623129352 11 P14923,Q13432,Q8WTV0 3 +Cell cell signaling by wnt 0.3463442699660987 0.800302035043996 0.4235358243077121 1.0 0.749077085344228 53 Q8IZT6,Q7KZI7,Q16539,P14923,Q13283,P19784,Q13043,O14745,Q9NVX2,P20339,P52294 11 +Regulation of protein import 0.400996651343436 0.7998924011897625 0.4237731407827001 1.0 0.7491766421503704 21 Q14978,Q16539,P14923,P06493,O75312,Q9UHD1,O14737,Q9BVL2,P08238 9 +Establishment of protein localization to vacuole 0.431266989061856 0.7995247349075053 0.4239862100760012 1.0 0.7491766421503704 14 Q96RL7,Q92783,P20645 3 +Muscle cell proliferation 0.3927305028207809 0.7993858240380143 0.424066727755056 1.0 0.7491766421503704 26 P52294,P31749,P09601,P04899,P04179,O95140 6 +Positive regulation of transcription by rna polymerase ii 0.2988338461776009 0.7956149249064587 0.4262558890004793 1.0 0.7503149381513873 141 O95747,Q03164,Q9NY61,Q9H2U1,Q08209,Q71SY5,Q969T9,O75448,Q14004,Q96ST3,Q8WWK9,Q96T37,Q7L2J0,Q96HY6,P17096,P31749,Q9NWH9,P43490,Q06265,P56545,P14923,Q13951,P46100,P51608 24 +Cell morphogenesis 0.2942007192671547 0.7917771591078258 0.4284906227443645 1.0 0.752989087672674 146 Q9UQB8,O75844,Q8TEY7,P20936,Q6IBS0,Q13596,Q7KZI7,Q9H2U1,Q96ST3,Q9Y639,Q9NWH9,P07196,Q9Y5P4,P26038,Q08209,P42574,Q9P265,Q13043 18 +Regulation of blood circulation 0.3982239634940792 0.7890347545612384 0.4300916938539647 1.0 0.7547325460266806 22 O75844,P78310,P14923,P15924 4 +Regulation of protein localization to cilium 0.7002474928178326 0.7878261691396089 0.4307983917068023 1.0 0.7549776525037031 3 Q10713 1 +Multivesicular body organization 0.5084036232843415 0.787362839094379 0.431069493869322 1.0 0.7550929990483267 9 Q8WUX9,O14964,O43633,Q92783 4 +Positive regulation of synaptic transmission 0.4288178496893239 0.7862743630200968 0.4317067685503617 1.0 0.7554310803957479 14 O95793,Q9Y639 2 +Negative regulation of neuron projection development 0.4254181474725617 0.7833572525503805 0.433417351376216 1.0 0.7565624406769691 15 Q14195,Q9P265 2 +Cardiolipin metabolic process 0.5398664163173216 0.7827047995632247 0.4338004831293074 1.0 0.7565624406769691 7 P51608,Q6UWP7,Q9UJZ1 3 +Canonical wnt signaling pathway 0.3829942248351932 0.7819304475610909 0.4342554500701943 1.0 0.7565624406769691 29 Q8IZT6,Q16539,P14923,Q13283,Q13043,O14745,P20339,P52294 8 +Ires dependent viral translational initiation 0.460720088648518 0.7814082123577779 0.4345624425463639 1.0 0.7565624406769691 12 P05455,Q15366,Q14152,Q9ULC4,O00303 5 +Antimicrobial humoral immune response mediated by antimicrobial peptide 0.5702956370062945 0.7795925043735061 0.4356307693125629 1.0 0.757685268693239 5 P05204,P39019 2 +Ribosome disassembly 0.5701524787147798 0.7790449522350071 0.4359532352433222 1.0 0.7578768522374273 5 P46199,Q9ULC4,Q96E11 3 +Pyruvate metabolic process 0.3575049948154419 0.7766559415364864 0.4373617872641528 1.0 0.7598185627005768 36 O15294,Q16822,P54619,P40763 4 +Positive regulation of cellular component biogenesis 0.3096308746420113 0.7742376185461813 0.4387902859412378 1.0 0.7599123502219126 99 Q9UQB8,Q14195,Q6IBS0,Q96ST3,P51608,Q9NQW6,Q9NWH9,P26038,P49593,Q71SY5,Q92783,Q9UNE7,Q9NVN8 13 +Enzyme linked receptor protein signaling pathway 0.3105982344665607 0.7740108376209947 0.4389243823420632 1.0 0.7599123502219126 106 Q9UQB8,P20936,O43318,P43490,P31749,Q9Y639,Q9NWH9,P31751,P04792,O95470,P04899,Q9UNE7 12 +Regulation of heart rate by cardiac conduction 0.6794814022126981 0.7738489938974632 0.4390200955295977 1.0 0.7599123502219126 4 P14923 1 +Iron sulfur cluster assembly 0.4749396822975404 0.7737988191792573 0.4390497709232717 1.0 0.7599123502219126 11 O75027 1 +Epithelial cell cell adhesion 0.6786340825557106 0.7709153449650683 0.4407571110327735 1.0 0.7612698960397771 4 P14923 1 +Fat cell differentiation 0.3905845391415688 0.7706959849279279 0.4408871523656481 1.0 0.7612698960397771 25 P31749,Q16539,P56545,Q9NZ08,P31751,Q8N4Q0,Q9C0B1,Q00839,P04179,Q13043 10 +Cytochrome complex assembly 0.473902681576846 0.7688939086358695 0.4419562938313564 1.0 0.7622267247340028 11 Q69YU5,Q15070 2 +Positive regulation of blood vessel endothelial cell migration 0.4735441917259118 0.7671995930972497 0.4429628548006321 1.0 0.7637540866223897 11 P09601,P31749 2 +Regulation of cellular carbohydrate metabolic process 0.3899999187437858 0.7668666528847785 0.4431608022664433 1.0 0.7637540908972323 25 O75844,P31749,P31751,P40763,Q13043 5 +Cerebral cortex development 0.3933639563763901 0.766465954493832 0.4433991019451946 1.0 0.7638804719459642 23 Q96P11,P07196,Q8IZT6 3 +Negative regulation of activated t cell proliferation 0.6939397658700663 0.7659987705747002 0.4436770337113718 1.0 0.7641507885579928 3 P42574 1 +Cellular response to heat 0.3944635588531174 0.7653370814267286 0.444070848545234 1.0 0.7646204902412347 22 Q9H2U1,Q9UNE7,P09601,O75190 4 +Axis specification 0.5524478290030945 0.7625936245164427 0.4457057879752408 1.0 0.7663608101131395 6 Q9Y2W6 1 +Negative regulation of receptor mediated endocytosis 0.5347832356033604 0.7620107010578929 0.4460536174124017 1.0 0.7663608101131395 7 Q13432 1 +Negative regulation of vascular associated smooth muscle cell proliferation 0.5656859849437958 0.7619987732376677 0.4460607363360664 1.0 0.7663608101131395 5 P09601 1 +Filopodium assembly 0.5023223286917473 0.7607172704393846 0.446825957066931 1.0 0.7668548771189462 9 Q14195,P20339 2 +Regulation of sprouting angiogenesis 0.6923076923076888 0.7603734775412041 0.4470313722980572 1.0 0.7669989360570472 3 P57105,Q07157 2 +Protein localization to nucleolus 0.4872029317492948 0.7596509354706908 0.4474632640611795 1.0 0.7673229357094752 10 Q76FK4 1 +Leukocyte homeostasis 0.45603654324458 0.7583317931548804 0.4482523787852797 1.0 0.7678398337696979 12 Q96EY1,P31749 2 +Negative regulation of proteasomal ubiquitin dependent protein catabolic process 0.4092235072089997 0.7567311771853266 0.4492109323467783 1.0 0.768843124111046 18 Q96HY6,Q9NZM5,P46379,Q04323 4 +Positive regulation of protein dephosphorylation 0.4712654944235681 0.7564458683204668 0.4493819159867636 1.0 0.768843124111046 11 Q14738,Q8IV63,Q92797,Q86XL3,P08238 5 +Positive regulation of dephosphorylation 0.4712654944235681 0.7564458683204668 0.4493819159867636 1.0 0.768843124111046 11 Q14738,Q8IV63,Q92797,Q86XL3,P08238 5 +Cellular response to oxygen radical 0.6742369309384322 0.7557301963066239 0.4498109756835926 1.0 0.768843124111046 4 P04179,P00374 2 +Response to oxygen radical 0.6742369309384322 0.7557301963066239 0.4498109756835926 1.0 0.768843124111046 4 P04179,P00374 2 +Epidermal cell differentiation 0.3791693174410275 0.7552672832069565 0.4500886249866129 1.0 0.7690021852070626 29 O75116,Q8WX93,Q9Y3B8,Q15149,O14745,P42574,Q14651,P18074,Q13043,Q9P0M6,P15924 11 +Response to cold 0.4552225674871548 0.7543339813317477 0.4506487025814254 1.0 0.7694418356136075 12 Q14011,P00403,Q13217,P07900,P17612,P04179,P20020 7 +Microtubule polymerization or depolymerization 0.3669448686572504 0.7539608431013705 0.4508727344757266 1.0 0.7696055204798776 33 Q8WWK9,Q99661,Q9NWH9,Q96S59,Q9BSJ2,Q96CW5,O00139,P51608,P16949,P29372 10 +Lymphocyte homeostasis 0.4857062872415408 0.7528701959484171 0.4515279194968495 1.0 0.7699733797343887 10 Q96EY1,P31749 2 +Embryonic placenta development 0.4704917102829915 0.7528005874061307 0.4515697537466647 1.0 0.7699733797343887 11 O75190,P31749 2 +Regulation of fatty acid transport 0.562956385974976 0.7516180271599084 0.4522807991373005 1.0 0.7707694914312864 5 P31749 1 +Homeostatic process 0.2902006506733844 0.7500709311981351 0.4532119858123398 1.0 0.7715532309099455 257 O95202,P78310,Q16822,P09455,Q9Y5P4,Q08209,O76024,Q6IAA8,Q8WTV0,P04899,Q9NRK6,Q9BWH2,O14773,Q9BS26,Q8TAD4,P54105,O75027,O95793,O15254,Q96ST3,Q9Y639,Q8NE86,P04792,Q96EY1,Q9H4M9,Q15067,P31749,P39019,Q16763,Q9NWH9,Q01469,Q96A33,P40763,P42785,Q9UII2,P23786,O00767,O95140,P07954,P30519,P09601,Q9NWS0,O14745,O15294,P42574,P04179,Q9Y3B8,P16949,Q8NE01 49 +Positive regulation of proteolysis involved in cellular protein catabolic process 0.3494729199880609 0.7500652176996204 0.4532154267331909 1.0 0.7715532309099455 37 P31749,Q9NZM5,P46379,Q96HY6,Q9UII2,Q9UNE7 6 +Negative regulation of lipid transport 0.688831243051733 0.7484229557861803 0.454205080383149 1.0 0.7715532309099455 3 P31749 1 +Regulation of cytoskeleton organization 0.3081716227169033 0.7483573653229136 0.4542446315437689 1.0 0.7715532309099455 115 Q9UQB8,P04350,Q7KZI7,P53367,P52565,P58546,P35609,Q6IBS0,Q12792,Q8WWK9,O95429,P20936,Q9NWH9,Q9BPX3,P53365,Q00839,P49593,Q8WUX9,O75116,O43633,Q9Y624,P51608,P16949,P29372 24 +Positive regulation of striated muscle cell differentiation 0.6719147320369498 0.747737746071921 0.4546183587909 1.0 0.7715532309099455 4 Q16539,Q9UGN5 2 +Maintenance of protein location in cell 0.4028307746383661 0.7467175793654002 0.455234056043043 1.0 0.7722589548242271 19 Q6IBS0,P31749,Q12792,Q96RL7,O94901 5 +Malate metabolic process 0.5615204548198828 0.7461686936085239 0.4555655170877504 1.0 0.7724061962653211 5 P07954,P23368,P40925 3 +Regulation of actin filament based movement 0.5613126587924786 0.7453807827719218 0.4560415578986543 1.0 0.7725909301239879 5 P14923 1 +Vitamin transmembrane transport 0.5476812909648924 0.743957849112463 0.4569019759621957 1.0 0.7734260257976685 6 Q8WTV0 1 +Response to iron ion 0.670453535957009 0.7427185032503589 0.457652124911196 1.0 0.7742243181441284 4 P36551,P09601 2 +Metaphase plate congression 0.3795185760948415 0.7423685834880481 0.4578640487725967 1.0 0.7742243181441284 28 Q8WUX9,Q53HL2,Q53EZ4,Q99661,Q9BZD4,Q00839,P14635 7 +Homologous chromosome pairing at meiosis 0.51231218561931 0.7417570696643899 0.4582345354857202 1.0 0.774253455963687 8 P46379 1 +Organelle inheritance 0.4975688478420836 0.7400105681375397 0.4592935818352979 1.0 0.7753956352160617 9 Q13190,Q02750,Q99986,P36507 4 +Negative regulation of endocytosis 0.4973405678531997 0.739018966589173 0.4598954804065733 1.0 0.7759336308119031 9 Q13432 1 +Keratinocyte differentiation 0.3964890743805678 0.7387097215279179 0.4600832813193556 1.0 0.7759336308119031 20 O75116,Q8WX93,Q15149,P42574,Q9Y3B8,Q13043,Q9P0M6,P15924 8 +Positive regulation of erk1 and erk2 cascade 0.4199604110385776 0.7386752780217173 0.4601042011140051 1.0 0.7759336308119031 14 P04899 1 +Endoplasmic reticulum organization 0.3435557469652245 0.7382330273912234 0.4603728561424653 1.0 0.7759336308119031 41 P57088,Q8N4V1,Q9Y5P4,O95197,Q8NFQ8,Q96A33,Q9NPA0,Q9NXE4,P46379,Q5JRA6 10 +Intermembrane lipid transfer 0.528859639075606 0.7380310387984564 0.4604955878117505 1.0 0.7759336308119031 7 Q9Y5P4 1 +Signal release 0.3433937484604842 0.7367686186040806 0.4612630700295104 1.0 0.7760314342560684 43 P56545,O43768,Q16822,Q9P253,Q8NE86,Q08209,O15439,O95721,P20339 9 +Dendrite morphogenesis 0.3886164555664446 0.7363305205069199 0.4615295765901028 1.0 0.7760314342560684 23 Q9H2U1,Q9UQB8,Q08209 3 +Ventricular cardiac muscle cell action potential 0.6852487535640522 0.7361544797550318 0.4616366910145379 1.0 0.7760314342560684 3 P14923 1 +Desmosome organization 0.6852487535640522 0.7361544797550318 0.4616366910145379 1.0 0.7760314342560684 3 P14923 1 +Bundle of his cell to purkinje myocyte communication 0.6852487535640522 0.7361544797550318 0.4616366910145379 1.0 0.7760314342560684 3 P14923 1 +Regulation of ventricular cardiac muscle cell action potential 0.6852487535640522 0.7361544797550318 0.4616366910145379 1.0 0.7760314342560684 3 P14923 1 +Positive regulation of vasculature development 0.4136494414198525 0.7352541091560271 0.462184750966667 1.0 0.7765628737955077 16 P14923,Q9NZ08,P09601,Q86UE4,P04792,P40763 6 +Positive regulation of dendritic cell differentiation 0.5606498194945795 0.732506276326601 0.4638596132994357 1.0 0.7789387229714461 2 P09429 1 +Substantia nigra development 0.4130102296625484 0.7317391857921403 0.4643277740030753 1.0 0.7795175658217011 16 O75489 1 +Negative regulation of canonical wnt signaling pathway 0.4505228793798637 0.7313295561888086 0.4645778814769563 1.0 0.7795592108697267 12 Q16539,Q13043,O14745,Q13283 4 +Regulation of protein export from nucleus 0.4503134280195904 0.7303075012069876 0.4652022441046548 1.0 0.7803478058687375 12 Q9Y3B8 1 +Electron transport chain 0.3250133438682725 0.7284766994036628 0.4663218269750546 1.0 0.7805821886321567 65 Q13630,P13073,O75306,Q9H3K2,P51970,Q9UDW1,O75489,P15954,P14927,O43676,Q15149,Q16795,P04179,Q16718,O14949,P14635 16 +Regulation of cytoplasmic transport 0.4652539200658977 0.7282143466652075 0.4664823849310284 1.0 0.780643991109068 11 P26038,P35241,P53367,P36507 4 +Vitamin d metabolic process 0.5595667870036047 0.7278856430134661 0.4666835924560044 1.0 0.7807737686187631 2 P38435 1 +Glucose metabolic process 0.3397096694704359 0.7273127778704138 0.4670343722545333 1.0 0.7809784563964447 51 O75844,P31749,Q16539,P06733,Q16822,Q15120,P31751,P62136,Q01469,Q96C23,Q7Z4W1,Q92520,Q9BRR6,P04406,O15294,Q13043,Q9UBX3,P10253 18 +Cellular response to ketone 0.3943832033655526 0.7260469586617448 0.4678099836282907 1.0 0.7816227141119417 20 Q16822,P31749 2 +Mesenchymal cell differentiation 0.3721782379615019 0.723965047652933 0.4690871935313208 1.0 0.7821905097708829 30 O95747,Q8N5W9 2 +Neural nucleus development 0.4077059857063111 0.723788262840449 0.4691957361815058 1.0 0.7821905097708829 17 O75489 1 +Cellular response to endogenous stimulus 0.288713190750797 0.7236615385909687 0.4692735511058956 1.0 0.7821905097708829 202 Q9UQB8,Q16822,P33527,P35609,P04899,O75844,Q969T9,Q96ST3,Q9Y639,O43237,Q96HY6,O43318,P31749,P31751,P42785,P43490,O15173,P14923,O14737,Q9UNE7 20 +Hyaluronan biosynthetic process 0.5584837545126302 0.723272447206799 0.4695125169514802 1.0 0.7821905097708829 2 Q00610 1 +Regulation of hyaluronan biosynthetic process 0.5584837545126302 0.723272447206799 0.4695125169514802 1.0 0.7821905097708829 2 Q00610 1 +Hyaluronan metabolic process 0.5584837545126302 0.723272447206799 0.4695125169514802 1.0 0.7821905097708829 2 Q00610 1 +Regulation of keratinocyte differentiation 0.5250435406871886 0.7226653914456911 0.4698854829509118 1.0 0.7822922597646609 7 Q9P0M6 1 +Organic hydroxy compound transport 0.3807639825006915 0.720021171104056 0.4715119605557127 1.0 0.7834640282469322 26 Q14728,Q8WTV0 2 +Cell communication involved in cardiac conduction 0.4928566329785511 0.7195962219193931 0.4717736388749447 1.0 0.7836829139322286 9 P14923,P78310 2 +Respiratory burst 0.6633823098718108 0.7185399525369536 0.4724244228142229 1.0 0.7839155048927152 4 P39019 1 +Positive regulation of cellular protein catabolic process 0.3410954335187548 0.7178592029663264 0.4728441050410361 1.0 0.7840394480825805 44 P31749,P26038,Q9NZM5,P46379,Q96HY6,Q9UII2,Q9UNE7 7 +Late endosome to vacuole transport 0.6619330004811249 0.7136078604242324 0.4754696956409301 1.0 0.7877501071311552 4 Q8WUX9,Q92783 2 +Positive regulation of protein localization 0.3059813185778211 0.7133659466035851 0.4756193395324648 1.0 0.7877913194669419 108 P31749,Q9Y282,Q9C0E2,Q16822,Q9Y639,P31751,Q8NE86,P26038,O14737,Q96HY6,Q9Y3B8,Q9NVN8 12 +Regulation of filopodium assembly 0.5050610268989912 0.7114912619791991 0.4767798636889333 1.0 0.7886860938044938 8 Q14195,P20339 2 +Positive regulation of histone modification 0.3612369659383099 0.7114844200853572 0.476784102003762 1.0 0.7886860938044938 33 Q969T9,Q03164,Q9UHR5,Q9NWS0,P61088,P51608 6 +Neutral lipid metabolic process 0.4762878276707915 0.7104744171590811 0.4774099898943964 1.0 0.7895145825545361 10 Q16822,Q8NCC3,Q8WTV0 3 +Response to oxygen levels 0.3349005702684367 0.7096342132435949 0.4779309975243189 1.0 0.7899304378942721 55 P31749,P30519,P09601,Q9NZM5,P00846,P42574,Q9UNE7 7 +Positive regulation of dna ligation 0.554151624548731 0.7048958554811532 0.4808750495646485 1.0 0.7915691151775825 2 P09429 1 +Glycoprotein biosynthetic process 0.3484615844085513 0.7048052222705838 0.4809314581976709 1.0 0.7915691151775825 36 P04843,P46977,Q9NY61,P35610,Q92542,Q8TCJ2,O60762,O60701,O60502,P04844,O15294,Q9NYU2 12 +Regulation of reactive oxygen species biosynthetic process 0.5205449920074139 0.7046399668457107 0.4810343197555249 1.0 0.7915691151775825 7 O75027 1 +Response to oxygen containing compound 0.2896292590982086 0.703662895468887 0.4816427326260144 1.0 0.7923637868162207 235 Q9UQB8,O95747,Q86U42,Q9H2U1,Q02952,Q16822,P07196,Q08209,P33527,Q8WTV0,P35609,P04899,Q6IBS0,Q969T9,Q96ST3,P26038,O00487,P31749,Q9NWH9,P31751,P40763,P43490,O00767,P61353,P14923,P00374,P09601,Q9NWS0,O14745,P42574,P04179,O15294 32 +Microtubule polymerization 0.3802167959307792 0.7032910847344737 0.4818743654940745 1.0 0.7924027519625346 25 Q9NWH9,Q96S59,Q9BSJ2,Q96CW5,P51608,P16949 6 +Phospholipid dephosphorylation 0.550097223258479 0.7031195989423755 0.4819812191491379 1.0 0.7924027519625346 5 Q01968 1 +Positive regulation of amyloid precursor protein catabolic process 0.5497672276031321 0.7018843763127142 0.482751273111663 1.0 0.7930950018347482 5 O75116,P42574 2 +Regulation of mitochondrial membrane potential 0.3951523784752041 0.7017242809763874 0.4828511275469913 1.0 0.7930950018347482 19 Q9UII2,O75915,P31749 3 +Protein localization to chromosome 0.3392462451116963 0.7014587451783755 0.4830167718910574 1.0 0.7930950018347482 43 Q8WUX9,Q7Z5K2,P50748,P46100,O14773,Q9P0M6,Q9NVN8 7 +Regulation of glucose metabolic process 0.384163441811044 0.7010731038791249 0.4832573944009812 1.0 0.7930950018347482 22 O75844,P31751,P31749 3 +Cellular response to topologically incorrect protein 0.3430473991498451 0.6980307381755696 0.4851579711838967 1.0 0.7944281354405973 37 P57088,O76024,Q9BUN8,Q9NRK6,P46379,Q96HY6,Q9UER7,Q9UNE7,Q9NYU2 9 +Regulation of transcription of nucleolar large rrna by rna polymerase i 0.4587302574413902 0.6978226051693196 0.4852881403855533 1.0 0.7944281354405973 11 Q9NZM5,Q9P0M6 2 +Steroid esterification 0.6738894907908923 0.6975849963819433 0.4854367672530442 1.0 0.7944321940091024 3 Q6IAA8,P35610 2 +Cardiac ventricle development 0.4585737588982693 0.6970968491879439 0.4857421858999924 1.0 0.7944321940091024 11 O75844,Q96T37,P15924 3 +Positive regulation of cell population proliferation 0.304214688134427 0.6941898338850697 0.4875631671825542 1.0 0.796294319087079 114 O95140,Q96HY6,O95747,P43490,Q8IZT6,P31749,Q7Z5K2,Q14004,P51608,P62244,P09601,P31751,P40763,P04899,Q52LJ0,P14635,Q96EY1 17 +Fear response 0.6724449259660454 0.6927180106810259 0.4884865340380644 1.0 0.7971803237829093 3 P51608,Q04637 2 +Animal organ morphogenesis 0.3073347961581897 0.6925202347228278 0.4886106830915202 1.0 0.7971803237829093 80 O75844,O95747,Q9Y5P4,P26038,P80723,O95470,Q96A65,Q8N5W9 8 +Regulation of golgi organization 0.5146814350416755 0.6812966881019832 0.495683778494645 1.0 0.804928623329682 7 Q02750,P50570,P36507 3 +Respiratory system process 0.5139765565275507 0.6785025854904702 0.4974530850624163 1.0 0.8061643043859088 7 P51608,Q9C0B1 2 +Positive regulation of protein metabolic process 0.2802941391305882 0.6779958724811797 0.4977743102576548 1.0 0.8062973306738924 286 O75832,Q03164,Q7KZI7,Q9H2U1,P11940,P36507,P58546,Q9P265,Q9UER7,P14635,Q969T9,O75915,Q9Y376,Q9Y639,P26038,Q13217,Q96HY6,Q13432,O00487,O43318,P31749,Q9UHR5,Q16763,P31751,Q9H074,Q9BUN8,Q9NZM5,Q9UII2,Q13043,P49593,Q96P11,P46379,P42574,O14737,P51608,Q9UNE7 36 +Positive regulation of histone ubiquitination 0.6679643434605749 0.6776794495295709 0.4979749591288336 1.0 0.806415463436639 3 O75150 1 +Regulation of sister chromatid cohesion 0.4688404620498221 0.6773183392827271 0.4982039975054713 1.0 0.8065794974998834 10 Q7Z5K2 1 +Tor signaling 0.3854758530603206 0.6729486966206815 0.5009799302529605 1.0 0.8100351548315474 20 O75844,P31749,Q9NWS0,Q6IAA8,Q96B36 5 +Phosphatidylinositol biosynthetic process 0.4049086625538394 0.6725010591037823 0.5012647661039726 1.0 0.8100808121782654 15 Q92643,Q9NX62,Q01968 3 +Auditory receptor cell morphogenesis 0.6659843546424955 0.671062090777252 0.5021809756070701 1.0 0.8111289026019252 3 O14745 1 +Organic hydroxy compound biosynthetic process 0.334693009330861 0.6706756661781167 0.5024271678929568 1.0 0.8111289026019252 48 Q15392,O00764,P00374,Q16822,Q15800,Q16850 6 +Regulation of vesicle mediated transport 0.3014794454974927 0.6664632290627813 0.5051150593809328 1.0 0.8138808729139018 101 Q8NBU5,P53367,P30533,Q08209,Q8WTV0,P36507,P35609,P04899,Q92783,P57105,O75608,Q4V328,Q9P253,P26038,Q13432,Q9H4M9,P31751,P20339,O43633,P20337,P09601,Q96T51 22 +Glycine biosynthetic process 0.6645826743923314 0.6663882146330288 0.5051629934985082 1.0 0.8138808729139018 3 P00374 1 +Carboxylic acid transport 0.3610681669463232 0.6648967643685213 0.5061165254090887 1.0 0.8147934067906645 31 O75915,Q9H2D1,P33527,O15439,Q9BQT8,Q9UBX3 6 +Erbb signaling pathway 0.3885718871846061 0.6636026379109771 0.5069446685144343 1.0 0.815710661824704 19 P31749 1 +Negative regulation of developmental process 0.296120196858466 0.6586778017611445 0.5101026905337587 1.0 0.8174029387073481 88 O95747,Q08209,Q9P265,Q8N5W9,P57105,Q14004,P62805,Q8N4Q0,Q9H7N4,Q96T37,Q96G23,Q04917,Q8IZT6,P40763,Q00839,Q13043,P51608,Q13951,P04179 19 +Maintenance of protein location 0.369036185501738 0.6578525981148523 0.5106328523610304 1.0 0.8174029387073481 27 O75832,Q6IBS0,P31749,Q12792,Q96RL7,O94901 6 +Vesicle docking involved in exocytosis 0.4783009142348129 0.6573259903270373 0.5109713282418431 1.0 0.8174029387073481 9 O15498,Q9P253,P56545 3 +Regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay 0.4351751138385058 0.657234008716763 0.511030461222495 1.0 0.8174029387073481 12 Q9H2U1,Q9H074,P11940,Q00839 4 +Chaperone mediated autophagy 0.5085458161679695 0.6570664427281546 0.5111381949474021 1.0 0.8174029387073481 7 Q9UNE7 1 +Nucleosome positioning 0.478109715292922 0.6565166378081704 0.5114917660488965 1.0 0.8174029387073481 9 P10412,O60264,P16403,Q92522,P07305 5 +Dna dealkylation involved in dna repair 0.6615504784769388 0.6563083432500462 0.5116257504241017 1.0 0.8174101690733245 3 P29372 1 +Negative regulation of protein catabolic process 0.33296814415217 0.6552871849704495 0.5122828700619755 1.0 0.8178392014086759 38 P10619,P19784,Q9NZM5,P46379,Q04323,P60520,Q16850,Q96HY6,O15294 9 +Xenobiotic transport 0.5368239830388313 0.6538430313069465 0.5132129398146881 1.0 0.818891795540863 5 P33527 1 +Oligodendrocyte differentiation 0.3947699905719837 0.6520554761682882 0.5143653851333454 1.0 0.8200696578742525 17 Q96P11,Q92542 2 +Developmental growth involved in morphogenesis 0.3562536982315085 0.6514291104884801 0.5147695241757397 1.0 0.8203374409616048 32 Q96ST3,Q9P265 2 +Extracellular vesicle biogenesis 0.4764777384528643 0.6496181280690722 0.5159389203790965 1.0 0.8213914128274371 9 Q8WUM4,O14964,O43633,Q92783 4 +Mitochondrial calcium ion transmembrane transport 0.4895849151768776 0.6478410746029055 0.5170877459294005 1.0 0.8226431869451026 8 Q8NE86 1 +Bone morphogenesis 0.5053520077397565 0.644537866938481 0.5192267107480204 1.0 0.8253770019292549 7 O75844 1 +Chromosome localization 0.3550577435406362 0.6429103099468509 0.5202822991559466 1.0 0.826035072300356 32 Q8WUX9,O94901,Q53HL2,Q53EZ4,Q99661,Q9BZD4,Q00839,P14635 8 +Regulation of vascular permeability 0.64081937629912 0.6427516332854943 0.5203852715952688 1.0 0.826035072300356 4 Q02952,Q15149 2 +Regulation of small molecule metabolic process 0.3321318889568228 0.6419082793754518 0.5209327381844835 1.0 0.8260964714031985 44 O75844,P31749,P31751,Q01469,P40763,O15294,Q13043 7 +Interleukin 10 production 0.6401734104046181 0.6406152574594138 0.5217726841868793 1.0 0.8260964714031985 4 P09429,P40763,Q08722 3 +Amino acid import 0.5203761111692053 0.6391851008190171 0.522702523447709 1.0 0.8265272822855702 6 O14745,O75915 2 +Head development 0.2965522425463 0.6382768797736498 0.5232934594822929 1.0 0.8265272822855702 127 O94901,Q9UQB8,P28370,Q96P11,Q8IZT6,O75489,Q15102,Q96ST3,P07196,Q08209,P80723,P46379,O95470,P46100,P51608,P42574,P58546,O95456 18 +Regulation of endothelial cell differentiation 0.532298645100775 0.6372460676483631 0.5239645748217645 1.0 0.8265272822855702 5 O75116 1 +Protein refolding 0.4454349700961999 0.6367748473395408 0.5242715120357619 1.0 0.8265272822855702 11 P10809,P11142,O60884,Q0VDF9,P62942,P07900,Q9UL15,P0DMV9 8 +Regulation of megakaryocyte differentiation 0.5195258649205917 0.6359840304157158 0.5247868308308281 1.0 0.8265272822855702 6 Q96T37 1 +Dna replication synthesis of rna primer 0.6387283236994192 0.6358432087208589 0.5248786214491736 1.0 0.8265272822855702 4 Q14181,P49642,P09884 3 +Positive regulation of interleukin 1 production 0.5193816617454476 0.6354415304358274 0.5251404891754081 1.0 0.8265272822855702 6 P04792 1 +Cardiac muscle cell proliferation 0.6383670520231222 0.6346517678853415 0.5256555571285555 1.0 0.8265272822855702 4 Q16539,P10644,P06493 3 +Error free translesion synthesis 0.53718411552346 0.6341942424089032 0.525954064592328 1.0 0.8265272822855702 2 P28340 1 +Ceramide metabolic process 0.3914977479061673 0.6341668995108017 0.5259719069089992 1.0 0.8265272822855702 17 Q9Y5P4,Q8NCC3 2 +Glycerophospholipid metabolic process 0.3305784116276673 0.6327643298144108 0.5268875536042152 1.0 0.8272599254430483 47 O95674,Q92643,Q01968,Q8NCC3,P35790,Q01469,Q8WTV0,P51608,Q9NX62,Q8N2K0 10 +Positive regulation of arp2 3 complex mediated actin nucleation 0.5368231046931351 0.6327137137698131 0.5269206127391453 1.0 0.8272599254430483 2 Q7L576 1 +Regulation of cellular ketone metabolic process 0.4149054864683619 0.6317138564654208 0.5275738719866798 1.0 0.8275532144196579 13 Q01469,P31749 2 +Cardiac muscle cell action potential 0.4580238467822137 0.6298150660241386 0.5288155872836149 1.0 0.8279583256475103 10 P14923,P78310 2 +Glycerolipid metabolic process 0.327422887542129 0.6286691755190897 0.5295656622362679 1.0 0.8280573998257291 53 O95674,Q92643,Q01968,Q16822,P35790,Q01469,Q9NX62,Q8WTV0,P51608,Q8NCC3,Q8N2K0 11 +Ubiquitin recycling 0.6527516724436526 0.6273072196510829 0.5304578718484718 1.0 0.8280573998257291 3 Q16763 1 +Stress activated protein kinase signaling cascade 0.3425266053063238 0.6271089791753022 0.5305878016692185 1.0 0.8280573998257291 35 O75844,O43318,O75915,Q969S3,P36507 5 +Glycerolipid catabolic process 0.4708253134901545 0.6258633271689261 0.5314045904488207 1.0 0.8280573998257291 9 Q8NCC3,Q8WTV0 2 +Response to gamma radiation 0.3930854355609208 0.6239545905014415 0.532657407358907 1.0 0.8295179479345893 16 O75844 1 +Placenta blood vessel development 0.5159922408703534 0.622724858844674 0.5334653440169892 1.0 0.8300394731698545 6 P31749 1 +Positive regulation of cell cycle phase transition 0.3293009495682235 0.6210695400985516 0.5345538695953227 1.0 0.830914114383276 40 P31749,Q96ST3,Q96HY6,P51608,P14635 5 +Cellular ketone metabolic process 0.3591955483795638 0.6189774866986165 0.535931190209846 1.0 0.832645062742364 29 P22570,P31749,Q06136,P31751,Q01469 5 +Hormone metabolic process 0.3590690017189429 0.6181323610350918 0.536488091976334 1.0 0.8333052429861186 29 P09455,O75844,Q9UNE7,O95470 4 +Histone phosphorylation 0.3943822460122412 0.6170129961446066 0.5372261536204843 1.0 0.8338362669517546 15 O75844,Q8IV63,Q99986,Q13043 4 +Acetyl coa biosynthetic process 0.4818289259381253 0.6164901662732061 0.5375710601672139 1.0 0.8339769823708821 8 P11177,P24752,P10515,Q15120,P35610,P53396 6 +Phenotypic switching 0.6494035073973472 0.6163728354764678 0.5376484776025023 1.0 0.8339769823708821 3 P04179 1 +Positive regulation of exosomal secretion 0.4815724659290757 0.61546034749083 0.5382507482476497 1.0 0.8339914661191804 8 Q8WUM4,O14964,O43633,Q92783 4 +Regulation of exosomal secretion 0.4815724659290757 0.61546034749083 0.5382507482476497 1.0 0.8339914661191804 8 Q8WUM4,O14964,O43633,Q92783 4 +Positive regulation of molecular function 0.2806552809125086 0.6150760290442645 0.5385045117318459 1.0 0.8341799526680261 272 O75832,Q8TEY7,Q03164,Q7KZI7,Q969S3,Q08209,P07305,Q8WTV0,P36507,P35609,Q5JTV8,P04899,Q71SY5,P58546,P14635,O75915,Q9Y376,Q96HY6,Q13432,P20936,O00487,O43318,P31749,Q16763,Q9NWH9,P31751,Q04837,Q9BUN8,P60520,Q13043,P49593,Q9Y3P9,P56545,P14923,P00374,O14737,Q9UNE7 37 +Regulation of amyloid fibril formation 0.6320119295848023 0.6137983194359358 0.5393486079326177 1.0 0.8343882701622808 4 Q99471,O15212 2 +Negative regulation of amyloid fibril formation 0.6320119295848023 0.6137983194359358 0.5393486079326177 1.0 0.8343882701622808 4 Q99471,O15212 2 +Regulation of fatty acid metabolic process 0.4402610598761997 0.6133790642280085 0.5396257257984356 1.0 0.8343882701622808 11 Q01469,P31749 2 +Ribosomal small subunit assembly 0.4258490078598645 0.6130970374761275 0.5398121789711743 1.0 0.8343882701622808 12 P62841,O75616,P39019,P62263,P08865 5 +Nucleolar large rrna transcription by rna polymerase i 0.3960077126987662 0.6130486682284579 0.5398441600268993 1.0 0.8343882701622808 14 Q9P0M6,O15160,Q9NZM5,Q9NWS0 4 +Positive regulation of establishment of protein localization 0.3079702660834598 0.6122709287549452 0.5403585204430237 1.0 0.8345948380815195 73 Q9C0E2,Q9Y282,Q16822,P31751,Q8NE86,O14737,Q9Y3B8 7 +Morphogenesis of an epithelium 0.327104388775207 0.6118018914824387 0.5406688381381053 1.0 0.8348699056013688 50 O95747,Q9NWH9,P26038,Q96T37,Q13043 5 +Regulation of striated muscle cell differentiation 0.453816622600167 0.6115678173946684 0.5408237361860024 1.0 0.8349049071585377 10 Q16539,P67809,Q9UGN5,P42345,Q15014,Q9BYT8 6 +Regulation of protein complex stability 0.631171374437533 0.6110553724102621 0.5411629230121726 1.0 0.8349361965408771 4 Q7Z392,Q9BQ95 2 +Response to corticosteroid 0.3653391029347342 0.6087600249976908 0.5426835139270583 1.0 0.8368164524853825 25 Q16822,P07196,P61353 3 +Ribonucleoprotein complex disassembly 0.5243182295659484 0.6082526161548674 0.5430199424604178 1.0 0.836880079704806 5 Q9UBB9 1 +Regulation of chromosome condensation 0.479542901146966 0.6073266123116505 0.5436341807227154 1.0 0.8372973518762977 8 O95347,Q7Z5K2,O60264,Q9BPX3 4 +Positive regulation of phosphoprotein phosphatase activity 0.6296965317919008 0.6062513806107863 0.5443478385591749 1.0 0.8372973518762977 4 Q8IV63,P42345,P08238 3 +Positive regulation of phosphatase activity 0.6296965317919008 0.6062513806107863 0.5443478385591749 1.0 0.8372973518762977 4 Q8IV63,P42345,P08238 3 +Peptidyl proline modification 0.3551022096243867 0.606164513951365 0.5444055144299609 1.0 0.8372973518762977 30 Q9Y680,Q9Y3C6,Q9BV86,Q9Y237,O95302 5 +Negative regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay 0.4660430667381784 0.6059415611605223 0.5445535597661815 1.0 0.8372973518762977 9 Q9H074,P11940 2 +Crd mediated mrna stabilization 0.4660430667381784 0.6059415611605223 0.5445535597661815 1.0 0.8372973518762977 9 Q9H074,P11940 2 +Viral translation 0.3921396013106231 0.6053373434132108 0.5449548735828285 1.0 0.8375961713247271 15 P05455,Q15366,Q14152,Q9ULC4,O00303 5 +Cellular response to ether 0.529963898916962 0.6047875157279418 0.5453201897891224 1.0 0.8377802464419063 2 Q6PKG0 1 +Positive regulation of protein phosphorylation 0.2920972046939617 0.6047576925327158 0.5453400083744433 1.0 0.8377802464419063 89 O75832,O43318,P31749,Q7KZI7,Q9Y376,Q9Y639,P31751,Q9UER7,P36507,Q96HY6,Q13432,Q13043,P14635 13 +Activation of phospholipase d activity 0.6448769439926899 0.601682882303821 0.547385246497605 1.0 0.8386457145583102 3 P40616 1 +Calcium ion import 0.437586981896668 0.6013739536178858 0.5475909428135015 1.0 0.8386457145583102 11 O75844 1 +Reactive nitrogen species metabolic process 0.3913640135767939 0.6013122208658623 0.5476320513791613 1.0 0.8386457145583102 15 O75116,O43169,P31749,Q08722,P04179,Q5VT66,P50570 7 +Developmental growth 0.2922384067996511 0.6005594116184809 0.548133478651601 1.0 0.8388062976747962 90 O75844,Q8IZT6,P31749,Q96ST3,P58546,Q08209,P58107,P80723,Q9UGN5,O95470,P46100,Q9P265,Q13043 13 +Rna mediated gene silencing by inhibition of translation 0.5220700913089238 0.6001515751311317 0.5484052229681406 1.0 0.8390187976304435 5 P40763 1 +Apoptotic mitochondrial changes 0.3487643399722195 0.5984892249177508 0.5495135464478387 1.0 0.8403072250597369 32 O75832,P31749,O14737,Q9UII2,Q9Y3B8 5 +Regulation of dna ligation 0.643421999428591 0.5969844122695848 0.5505177877555791 1.0 0.8411974865503522 3 Q9UBB9 1 +Golgi disassembly 0.6264450867052019 0.5957006726096835 0.5513752087977954 1.0 0.8417891697796154 4 Q99986,Q13190,P06493 3 +Regulation of phosphorus metabolic process 0.2804788401246593 0.5954402562859081 0.5515492232148034 1.0 0.8417891697796154 197 O75832,Q7KZI7,Q969S3,Q8WTV0,P36507,P04899,Q9UER7,P14635,Q9Y376,Q9Y639,P04792,Q13217,Q96HY6,O95429,Q13432,O43318,P31749,O43768,Q9NWH9,P31751,Q99640,Q9NZM5,P40763,Q13043,P49593,Q9NWS0,O14745,O15294,P42574,Q9Y3B8 30 +Negative regulation of blood vessel endothelial cell migration 0.5200679334660633 0.592962564568541 0.5532062057384879 1.0 0.8435446966188352 5 P14923 1 +Fatty acid catabolic process 0.3259330063256757 0.5921822659649127 0.5537285434151078 1.0 0.8440951287114897 41 Q15067,P31749,O15254,Q16822,P31751,Q8NCC3 6 +Sphingolipid metabolic process 0.3566947633190578 0.5902101844858677 0.555049745016869 1.0 0.8451835547561418 28 Q06136,Q9Y5P4,Q8NCC3,O95470 4 +Regulation of tissue remodeling 0.5189274308274678 0.5888784340988874 0.5559428255765435 1.0 0.8451835547561418 5 O75116,Q08209 2 +Dendrite extension 0.5259927797833877 0.5888032658943537 0.5559932547680206 1.0 0.8451835547561418 2 Q7L576 1 +Mitochondrial fission 0.4483162159779983 0.5879225314964446 0.5565842921564836 1.0 0.8451835547561418 10 Q8NE86 1 +Cellular carbohydrate metabolic process 0.3188832854391041 0.5874822825953638 0.5568798462369999 1.0 0.8454160613097038 58 O75844,Q01968,P31749,Q9NUJ1,Q16822,P31751,Q13043,P40763,P51608,Q9NX62 10 +Positive regulation of interleukin 12 production 0.6399422174070103 0.5857940867364054 0.5580138979530518 1.0 0.8460560709797604 3 Q16539,P09429 2 +Positive regulation of interleukin 10 production 0.6399422174070067 0.5857940867363929 0.5580138979530602 1.0 0.8460560709797604 3 P09429,P40763 2 +Cellular response to alkaloid 0.6233411903012748 0.5856814434376589 0.5580896064546064 1.0 0.8460560709797604 4 P42574 1 +Negative regulation of gluconeogenesis 0.6398005842756019 0.5853400428207435 0.5583190951673576 1.0 0.8460560709797604 3 Q13043 1 +Polysaccharide biosynthetic process 0.3904602260699011 0.5847382684034498 0.5587237182135756 1.0 0.8460560709797604 14 P31749 1 +Midbody abscission 0.4898127202113204 0.5844822143728875 0.5588959278511025 1.0 0.8460560709797604 7 Q8WUX9,O43633,Q53EZ4,O95235,Q8WUM4 5 +L serine metabolic process 0.6229663176063525 0.584474918653839 0.5589008349788693 1.0 0.8460560709797604 4 Q9Y617,P34897 2 +Negative regulation of carbohydrate metabolic process 0.4606927141896125 0.5838563763511125 0.55931694490471 1.0 0.8462973273212289 9 Q13043,P40763 2 +Protein localization to phagophore assembly site 0.5051634274055029 0.5825628151618861 0.5601876437770599 1.0 0.8467859187953929 6 P53365,Q9Y4P1 2 +Locomotor rhythm 0.6388587937883702 0.5823237359801333 0.5603486403957147 1.0 0.8467877302558937 3 P42345,P54802 2 +Amyloid beta clearance by transcytosis 0.6219805322314798 0.5813058669689418 0.5610343271543126 1.0 0.847401861147774 4 P20339 1 +Negative regulation of epithelial cell migration 0.4598364749200884 0.580342743051316 0.5616835086080483 1.0 0.8480319639768572 9 P14923,P51608,P58107 3 +Wound healing 0.3229586827792775 0.5800312433289154 0.5618935487402532 1.0 0.8481462746225099 51 Q8WUX9,P09601,Q08209,P04792,P58107,P42785,Q8WTV0,P42574,Q9BWH2,P15924 10 +Dna dependent dna replication 0.3070904653670514 0.5788116328224011 0.5627162810074748 1.0 0.8486426947482058 70 P18858,O75844,O94761,Q04837,Q07864,P17096,Q96EY1 7 +Exocytic process 0.3812187019412646 0.5787467725201659 0.5627600511420237 1.0 0.8486426947482058 17 P56545,Q9P253,O00161,O95721,O15498 5 +Dna unwinding involved in dna replication 0.3771601412219498 0.5763944190111729 0.5643486158629853 1.0 0.8498204532694704 18 O94761,P17096 2 +Negative regulation of endothelial cell proliferation 0.5144816556335461 0.5730361915508908 0.5666201894121059 1.0 0.8516220560019166 5 Q9UII2 1 +Negative regulation of atp dependent activity 0.4862599737106308 0.5709789775838194 0.5680138932216845 1.0 0.8516220560019166 7 Q15070 1 +Regulation of ubiquitin protein transferase activity 0.3679130217264437 0.5708464132856801 0.5681037579742372 1.0 0.8516220560019166 20 P62841,Q9UNE7,Q16763 3 +Locomotory behavior 0.3573766894281678 0.569893715314441 0.5687497877181558 1.0 0.8519777365723453 26 O75844,P04179,Q96RL7,P51608,Q8N2K0 5 +Carbohydrate transport 0.3852044892528803 0.5695884909338436 0.5689568362797159 1.0 0.852085736306956 15 Q01469,P31749 2 +Mitochondrion localization 0.3824996086386508 0.5683414871695242 0.5698031134991957 1.0 0.8526191496113548 16 Q7KZI7 1 +Central nervous system development 0.2699068749419965 0.5680688918916955 0.5699881898177903 1.0 0.8526191496113548 156 Q9UQB8,Q15102,P68402,P07196,Q08209,P58546,O14773,Q96ST3,Q92542,P28370,Q16851,P18074,O95456,Q9P0M6,O14949,Q04917,Q8IZT6,O75489,P40763,Q9BPX3,P42574,Q13043,Q96P11,P51648,Q9BSJ2,P80723,P46379,P46100,O94901,Q9Y3C8,P51608 31 +Regulation of cell population proliferation 0.2801322084068143 0.5672354946432938 0.5705541957385243 1.0 0.8530232310826223 205 O95747,P04899,Q71SY5,P14635,O75844,Q15392,Q14004,P35244,Q96HY6,Q52LJ0,P17096,Q96EY1,Q9NTI5,Q96G23,P62244,Q8IZT6,P31749,P31751,P40763,P43490,Q9UII2,Q13043,O95140,Q7Z5K2,P56545,P14923,Q9NQG5,P09601,O14745,P58107,P42574,O14737,P51608,Q9Y3B8 34 +Regulation of muscle system process 0.3580783612801884 0.5637635561550294 0.5729150570837109 1.0 0.8545406623169318 25 O75116,Q12792,P06733,P14923,Q08209,Q9UGN5,P58546,P15924 8 +Protein methylation 0.318684979640731 0.5635914942940163 0.5730321767896562 1.0 0.8545406623169318 55 Q7L592,P10412,Q03164,P16403,Q9BV86,P51608,Q9NWS0,P46100,P22061,Q52LJ0 10 +Gastrulation with mouth forming second 0.6323923813394681 0.5617504557791282 0.5742860521711002 1.0 0.8550253473146275 3 Q4VCS5 1 +Defense response to bacterium 0.4147357012462296 0.5615294037486304 0.5744366912916943 1.0 0.8550253473146275 12 P39019,P81605 2 +Dicarboxylic acid transport 0.3858196675724687 0.5613223353484489 0.5745778180267671 1.0 0.8550253473146275 14 Q9BQT8,O75915,Q9H2D1 3 +Positive regulation of stress activated protein kinase signaling cascade 0.4551044961011627 0.5610322331193871 0.5747755637635215 1.0 0.8550253473146275 9 Q969S3,O75915 2 +Positive regulation of mitotic cell cycle phase transition 0.3481932692312681 0.5598537941557605 0.5755791675552497 1.0 0.8555100903822614 30 Q96ST3,P51608,P14635,P31749 4 +Intracellular protein transport 0.2757724415715636 0.5594019615051887 0.5758874230075697 1.0 0.8557668131018581 281 O60830,Q9Y276,Q99595,Q9C0E2,P53367,Q9Y5L4,Q08209,P08240,Q8IWJ2,Q92783,Q9NS69,P52294,Q4V328,Q13596,Q9P253,P04792,P20645,O95429,Q9Y584,Q5SRE5,Q9H4M9,O14925,P31749,Q10567,P31751,Q15070,Q9BUN8,P40763,P53365,Q9UII2,O94973,P20339,Q13043,O95140,O75436,Q99797,Q9Y282,P14923,Q9UI26,Q96RL7,Q8TAG9,P46379,O14737,O43592,Q9Y3B8 45 +Amyloid beta formation 0.4280524586716399 0.5590859232399595 0.5761030812728625 1.0 0.8557995374879265 11 O95197,Q16799,Q92542,P42574 4 +Aspartate metabolic process 0.6315132985906219 0.5589724465187133 0.5761805248433918 1.0 0.8557995374879265 3 P30520 1 +Glycerophospholipid biosynthetic process 0.3499196199464007 0.5577566718386784 0.5770105531991971 1.0 0.8566293517281285 29 O95674,Q92643,Q01968,P35790,Q01469,Q9NX62 6 +Regulation of protein serine threonine kinase activity 0.3210913861831913 0.5574467102017194 0.5772222589536238 1.0 0.8567422056965633 49 O75832,O43318,P31749,Q9Y376,Q9NWS0,Q99640,P36507,P42574,Q9Y3B8,Q13043,P14635 11 +Negative regulation of cellular component organization 0.27883424091275 0.5568598646552548 0.5776231783522814 1.0 0.8571357809909059 146 O75832,P30533,Q08209,P58546,Q9P265,P14635,Q6IBS0,Q12792,Q8WWK9,Q9UBB9,Q13432,Q96G23,Q04917,P31749,P50748,Q9NWH9,O75190,Q9NZM5,Q9BPX3,Q00839,O15212,Q9NVN8,O75116,Q14195,Q7Z5K2,P46100,Q9Y624,P16949,P29372 29 +Positive regulation of proteasomal ubiquitin dependent protein catabolic process 0.3582379260442548 0.5562110450424473 0.5780665895320953 1.0 0.8573907555333921 24 Q96HY6,Q9NZM5,Q9UNE7,P31749 4 +Cell junction organization 0.293271593071056 0.5554496495320688 0.5785871405449075 1.0 0.857743545442396 106 Q9UQB8,P15924,Q4V328,P56545,O95793,P14923,Q9H2U1,P78310,Q9Y639,P07196,P35609,P51608,P49593,Q96EY1 14 +Negative regulation of cell adhesion 0.3495373505835021 0.5552670838800076 0.5787119897980055 1.0 0.857743545442396 29 P20936,P31749,Q13951,P42574,Q5JRA6,P49593 6 +Positive regulation of ubiquitin protein transferase activity 0.4659344989475391 0.5535674178317025 0.5798749295980508 1.0 0.8581495250258238 8 Q16763,Q9UNE7 2 +Rrna transcription 0.3602678314448896 0.5533135421476097 0.5800487295919186 1.0 0.8581495250258238 21 O15160,Q9H9Y6,Q9NWS0,Q9NZM5,P19338,Q9P0M6 6 +Negative regulation of supramolecular fiber organization 0.32068131850973 0.5500204995037594 0.5823053132982663 1.0 0.8599008418395377 41 Q99471,P04350,Q6IBS0,P60983,Q12792,Q07157,Q8WWK9,P35241,Q9NWH9,P16949,Q92974,Q9BPX3,P58546,Q9Y624,O15212,P29372 16 +Positive regulation of transport 0.2799436176850974 0.549139643644708 0.5829096209945752 1.0 0.8601288494881393 144 Q03164,P31749,Q9Y282,Q9C0E2,P14923,Q16822,Q92783,P31751,Q8NE86,P26038,O14737,P04899,Q9UII2,Q9Y3B8,P20339,P35609,Q16630 17 +Regulation of ubiquitin protein ligase activity 0.4116615674509557 0.5474825664269909 0.5840472444198146 1.0 0.861097028741377 12 P62841 1 +Stem cell differentiation 0.3238678493254456 0.5474051206972927 0.5841004380521029 1.0 0.861097028741377 37 O95747,Q14004,Q9H2U1,Q14671,P40763,Q00839,P18074 7 +Negative regulation of mitochondrion organization 0.3828669165211011 0.5465568529639296 0.5846832186809181 1.0 0.8612880315423475 14 O75832,Q9H3K2,P02786,P31749 4 +Mammary gland morphogenesis 0.6104540368239618 0.5446614827128885 0.5859863604089743 1.0 0.8624517201916699 4 Q99623,P07384 2 +Small gtpase mediated signal transduction 0.293915439736585 0.5441698084570155 0.5863246258305828 1.0 0.862454122621291 80 P84095,P80303,Q13283,P52565,Q68EM7,Q9UHD1,P50570,P57105,Q15392,Q9UQ13,Q96EY1,P20936,P42771,Q9NWH9,Q9H0H5,Q92974,P53365,Q4VCS5,O95140,O75116,P09601,Q96T51,Q9Y624,O15294,P16949 25 +Myofibroblast differentiation 0.5144404332129906 0.5431246015867194 0.587044015074969 1.0 0.8629314153108975 2 P09874 1 +Cardiac epithelial to mesenchymal transition 0.5144404332129904 0.5431246015867187 0.5870440150749694 1.0 0.8629314153108975 2 Q9NQC3 1 +Insulin metabolic process 0.6262915192484505 0.5425668820104994 0.5874280464184873 1.0 0.8630452614422408 3 Q8TAD4 1 +Positive regulation of cytoplasmic transport 0.6096990072203688 0.5422884288296056 0.5876198256161218 1.0 0.8630452614422408 4 P26038 1 +Positive regulation of early endosome to late endosome transport 0.6096990072203688 0.5422884288296056 0.5876198256161218 1.0 0.8630452614422408 4 P26038 1 +Respiratory gaseous exchange by respiratory system 0.4503768324556806 0.5419279535919853 0.5878681389181346 1.0 0.8632091695649075 9 P51608,Q9C0B1 2 +Regulation of metallopeptidase activity 0.6258825369980592 0.5412890016096572 0.5883084000667183 1.0 0.8634540302234447 3 Q96HY6 1 +Lipid biosynthetic process 0.2906059131206556 0.5402246040202889 0.5890421468068479 1.0 0.8641292088611612 123 O95674,Q15392,P22570,P31749,Q06136,Q96PU8,Q16822,P35790,P09455,Q01469,Q15800,Q8WTV0,O95470,Q16850,Q8NCC3 15 +Positive regulation of histone acetylation 0.4775846505850399 0.538396316664223 0.5903034687344997 1.0 0.8651555251285534 7 Q969T9 1 +Negative regulation of apoptotic signaling pathway 0.3142653701745387 0.538265008870229 0.5903941048568795 1.0 0.8651555251285534 57 O75832,Q96QE3,Q9H3K2,Q9NY61,P31749,O75489,P06733,P19784,P09601,Q9NWS0,P32119,P04792,O76024,Q92974,Q9NVX2,P04899,P04179 17 +Regulation of organic acid transport 0.4365433321340631 0.5381850304806807 0.5904493136385465 1.0 0.8651555251285534 10 O75915,P31749 2 +Regulation of histone methylation 0.3502756948851324 0.5376221724773982 0.5908379195999878 1.0 0.8651555251285534 27 P51608,Q03164,Q9NWS0,P46100 4 +Histone h3 k27 methylation 0.4617328741837188 0.537262503951768 0.5910863019654955 1.0 0.865318551034115 8 O15294,P10412,P16403 3 +Dendrite development 0.3188010673915693 0.5369955620441983 0.5912706795798015 1.0 0.8653878235667284 40 Q9H2U1,Q9UQB8,P51608,Q08209 4 +Peptidyl serine dephosphorylation 0.4613914339634773 0.5359439679109157 0.5919972760226497 1.0 0.8660208695631143 8 P49593 1 +Carbohydrate transmembrane transport 0.4088962845348801 0.5349332267893843 0.5926960312431695 1.0 0.8665256997985821 12 Q01469,P31749 2 +Positive regulation of protein import 0.3755763025984523 0.5327107385989579 0.5942338313919084 1.0 0.8677133236374907 16 O14737,P14923 2 +Pteridine containing compound biosynthetic process 0.4601476111601516 0.5311490861082049 0.5953154713922846 1.0 0.8682887240403984 8 P00374 1 +Escrt complex disassembly 0.502324029522754 0.5303837246173291 0.5958459079708474 1.0 0.8688519870479574 5 Q8WUX9 1 +Late endosome to lysosome transport 0.5022122404231583 0.5299963275701367 0.5961144770180158 1.0 0.8688519870479574 5 Q8WUX9 1 +Regulation of oxidative stress induced intrinsic apoptotic signaling pathway 0.421260473566853 0.5294922035318952 0.5964640514449868 1.0 0.8691608633334057 11 P04792,P31749 2 +Regulation of hydrogen peroxide metabolic process 0.6053176389517203 0.5285868511511016 0.5970920836524822 1.0 0.8696746058089441 4 P04179,P32119 2 +Associative learning 0.4745676619839735 0.527201579615412 0.5980536118511794 1.0 0.8702210382402024 7 Q9Y639 1 +Response to electrical stimulus 0.5011067006386734 0.5261700488599227 0.5987700620869199 1.0 0.8709131932773121 5 P04179,Q02952 2 +Positive regulation of protein serine threonine kinase activity 0.3501741940836908 0.525361686986368 0.5993317821263462 1.0 0.87152945010266 26 O75832,O43318,P31749,Q9Y376,Q13043,P14635 6 +Amyloid beta metabolic process 0.3925403405644345 0.5238122852701392 0.6004091077424936 1.0 0.8728950279268027 13 O95197,Q16799,Q92542,P42574 4 +Regulation of metaphase plate congression 0.6193500637355471 0.5210208117429939 0.6023522735227465 1.0 0.8749142523631518 3 Q00839 1 +Regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway 0.4993265539906523 0.5200277788982364 0.6030442137576766 1.0 0.8749690449457147 5 Q9NVX2,Q9NWS0 2 +Positive regulation of transferase activity 0.2862768291176003 0.519972307172483 0.6030828767189975 1.0 0.8749690449457147 92 O75832,O43318,P31749,Q7KZI7,Q9BRX5,Q9Y376,Q16763,Q969S3,Q9NWH9,Q9NWS0,Q9UER7,P36507,P61088,Q13432,Q13043,Q9UNE7,P14635,P54619 18 +Tetrahydrobiopterin metabolic process 0.6019745554367542 0.5182131132169794 0.6043095865565888 1.0 0.8755417002107164 4 P00374 1 +Regulation of protein localization 0.2738782639744953 0.5170352252555396 0.6051315693525097 1.0 0.8763304424063638 188 Q9C0E2,Q16822,Q08209,P35609,Q16850,Q8IWJ2,Q4V328,Q96ST3,Q9Y639,Q8NE86,P26038,Q7L2J0,Q96HY6,P31749,O43768,P31751,O75190,Q9UII2,P49593,Q9NVN8,Q7Z5K2,Q9Y282,P14923,O14737,Q9Y3B8 25 +Mapk cascade 0.2872339902711027 0.5153334905338525 0.6063199998993858 1.0 0.8769761862314549 83 O75832,Q86U42,Q969S3,Q02952,Q6IAA8,P36507,P04899,Q9UER7,P57105,O75915,Q9Y639,O43318,Q15750,Q16539,Q8IV63,Q13043,O75116,Q96S59,O14745,P29372 20 +Regulation of lysosomal protein catabolic process 0.5072202166064921 0.5152397411706156 0.6063855014208961 1.0 0.8769761862314549 2 P04062 1 +Regulation of endothelial cell development 0.6010041389755851 0.5152152541911149 0.6064026106920184 1.0 0.8769761862314549 4 O75116 1 +Labyrinthine layer development 0.4559624654587036 0.5151138855322942 0.6064734401748924 1.0 0.8769761862314549 8 P31749 1 +Glucan biosynthetic process 0.4178950592074365 0.5150047058663059 0.6065497315921387 1.0 0.8769761862314549 11 P31751,P31749 2 +Dorsal ventral pattern formation 0.6172458823133622 0.5145506531612195 0.6068670557696036 1.0 0.8772341094618309 3 P17612 1 +Tissue development 0.2791209818881651 0.5139555359296699 0.6072830780959109 1.0 0.8776345514070911 231 O95747,Q9H9Y6,P78310,Q16822,Q08209,P58546,P35609,Q9NX62,Q8N5W9,O14773,O75844,Q15392,P26038,Q96T37,Q9UGN5,Q96HY6,Q96A65,P31749,Q9NWH9,P31751,Q01469,P43490,Q13043,Q9Y4P1,O15173,P51648,P58107,P80723,P46100,P42574,Q9Y3B8,P15924 32 +Response to catecholamine 0.389906838320478 0.5114793192199839 0.6090154660098679 1.0 0.8791320650174453 13 P17612,Q96ST3,O14745,Q92542 4 +Regulation of systemic arterial blood pressure 0.4967637899009443 0.5112265781392589 0.6091924100092223 1.0 0.8791864861253097 5 P51608,P42785 2 +Regulation of glucose transmembrane transport 0.4167228730977066 0.5099872199351245 0.6100604153300848 1.0 0.8800368888266291 11 Q01469,P31749 2 +Maintenance of apical basal cell polarity 0.6156409449663512 0.5096352272171244 0.6103070394484598 1.0 0.8801133042290468 3 O14745 1 +Monocyte chemotaxis 0.4956248408303761 0.5073310729464828 0.6119225396397874 1.0 0.8802549262765236 5 Q8NHP6,P39019 2 +Isopentenyl diphosphate biosynthetic process 0.598351904851815 0.5070530796678864 0.6121175755466788 1.0 0.8802549262765236 4 Q13907,Q15126 2 +Nuclear body organization 0.5982658959537537 0.5067891622030074 0.6123027615151238 1.0 0.8802549262765236 4 O75312,Q8NC51,Q9BUR4 3 +I kappab kinase nf kappab signaling 0.3152096908419008 0.5050900248138948 0.6134956072495723 1.0 0.8809603685270243 47 Q8TB61,O43318,P31749,Q8IUH4,P09601,P04792,Q96HY6 7 +Golgi to plasma membrane transport 0.3513562283122625 0.504857205375354 0.6136591333610739 1.0 0.8809603685270243 22 Q96KP1,Q8IWJ2,Q96A65,Q8TAG9 4 +Regulation of amyloid precursor protein catabolic process 0.3743233263998131 0.5044631206762702 0.6139359716554609 1.0 0.8809603685270243 14 O75116,O95197,Q16799,P42574 4 +Amino acid import across plasma membrane 0.5974360150663333 0.5042451946443613 0.614089084897206 1.0 0.8809603685270243 4 P08195,O75915 2 +Positive regulation of smad protein signal transduction 0.5043321299638931 0.5042380252312119 0.6140941223605467 1.0 0.8809603685270243 2 P09874 1 +Regulation of blood pressure 0.3721442501021496 0.5038870625457512 0.6143407424438043 1.0 0.8809782983852329 15 P51608,Q9NZ08,P09601,P42785 4 +Positive regulation of ubiquitin dependent protein catabolic process 0.3480594624059491 0.5031308553606172 0.614872274435198 1.0 0.8812661223515115 25 Q96HY6,Q9NZM5,Q9UNE7,P31749 4 +P38mapk cascade 0.5956254765027867 0.4987109708393116 0.6179830147038785 1.0 0.8837926964530666 4 O43318 1 +Interleukin 1 production 0.4652598641509012 0.4931383769619862 0.6219148159894285 1.0 0.8868315656927732 7 P04792 1 +Germ cell development 0.3241733547018306 0.4926748183337022 0.6222423733055911 1.0 0.8870712000567853 35 Q96PU8,Q9Y2W6,Q8IZT6,P31749 4 +Organic hydroxy compound catabolic process 0.3855719077252588 0.4913705472977111 0.6231643915433467 1.0 0.8881032738347194 13 Q01968,Q8WTV0 2 +Neuromuscular process controlling balance 0.4123142691715659 0.491252824980073 0.6232476411722587 1.0 0.8881032738347194 11 O14773 1 +Regulation of exocytosis 0.3272069570953128 0.49056116248955 0.6237368609834715 1.0 0.8885826436287779 34 P04899,P20339,P09601 3 +Cytoskeleton organization 0.2714381862573741 0.4891469737716789 0.6247376473949293 1.0 0.8893762823334194 284 P68371,Q9UQB8,P04350,Q8TEY7,Q01518,Q02241,Q8WX93,Q7KZI7,P78310,P29372,P07196,P53367,P52565,P58546,P35609,Q8IWJ2,P14635,Q8N5W9,Q6IBS0,Q12792,Q8WWK9,Q99661,Q9NQW6,Q8NE86,O43237,Q9BZD4,P26038,O95429,Q9HBM1,P20936,Q96JJ3,Q8IZT6,Q9NWH9,O75190,Q9H0H5,Q9BPX3,P53365,Q00839,P49593,O43663,Q8WUX9,P07197,Q14195,O75116,O00139,A0AVF1,O43633,Q9BV86,Q9NSV4,Q96S59,Q9BSJ2,Q96CW5,P58107,O14745,P46100,Q9Y624,O94901,P51608,P16949,P18583,P15924 61 +Dendritic cell differentiation 0.6082978591109853 0.4873675237340965 0.6259979039625196 1.0 0.8893762823334194 3 P01889 1 +Regulation of dendritic cell differentiation 0.6082978591109853 0.4873675237340965 0.6259979039625196 1.0 0.8893762823334194 3 P01889 1 +Liver regeneration 0.4486137924185089 0.4873400485181156 0.6260173712628561 1.0 0.8893762823334194 8 P09601 1 +Regulation of microtubule cytoskeleton organization 0.3129296378313645 0.4864063943089365 0.6266790578408847 1.0 0.8895799395699969 43 Q8WUX9,O43633,Q7KZI7,Q8WWK9,Q9NWH9,Q00839,P51608,P16949,P29372 9 +Dna ligation 0.4631240605684221 0.4854276356392402 0.6273730329189804 1.0 0.8897648988882395 7 P18858 1 +Protein catabolic process 0.2774810726675514 0.4852019222551677 0.6275331186372148 1.0 0.8897920752471086 232 Q8TEY7,Q9NUJ1,Q16850,Q92783,O14773,O75844,P49721,P26038,Q13217,O60502,Q96TA2,Q96HY6,Q8N2K0,P55036,O00487,P31749,Q16763,Q9BUN8,Q9NZM5,Q96A33,P60520,Q9UII2,Q9NYU2,Q8WUX9,Q96RL7,Q9Y508,Q9NXV2,P46379,Q9UHG3,Q9UNE7 30 +Isotype switching to igg isotypes 0.6073653905614689 0.4845664795070816 0.6279838963255122 1.0 0.8898840229354019 3 Q96QE3 1 +Positive regulation of developmental process 0.2652485842080527 0.4824156808894825 0.629510683910657 1.0 0.8909278539863289 166 Q9UQB8,O95747,Q8IZT6,P31749,Q96ST3,Q9NZ08,Q9Y639,P09601,Q8NE86,Q13951,P07196,P04792,P80723,Q9Y3B8 14 +Muscle contraction 0.3259059707972793 0.4815533968739163 0.630123238936517 1.0 0.8912630220979321 34 O75116,P15924,Q86U42,P06733,P14923,P17612,Q9Y5P4,P35609,P10253 9 +Negative regulation of cytoskeleton organization 0.3108659051044806 0.4811720144611085 0.6303942490652015 1.0 0.8912788248023363 38 Q96PK6,P04350,Q6IBS0,P60983,Q12792,Q07157,Q8WWK9,P35241,Q9NWH9,Q92974,Q9BPX3,P58546,Q9Y624,P16949,P29372 15 +Response to nutrient 0.3443384069737469 0.4810896578499885 0.630452778157832 1.0 0.8912788248023363 25 P04899,O43768 2 +Organic acid catabolic process 0.2879316819082378 0.4805539859336077 0.6308335253827622 1.0 0.8912788248023363 80 Q9BQT8,Q9HCC0,Q16822,Q8NCC3 4 +Response to immobilization stress 0.605994944023111 0.4804609207923155 0.6308996846273485 1.0 0.8912788248023363 3 P06744,P04179 2 +Response to muscle stretch 0.6052726616106904 0.4783024852844241 0.6324349277377388 1.0 0.8923338846337773 3 Q16539,P06744 2 +Regulation of morphogenesis of a branching structure 0.6052726616106869 0.4783024852844129 0.6324349277377468 1.0 0.8923338846337773 3 Q9NQC3,Q99623 2 +Cranial nerve development 0.6052726616106853 0.4783024852844085 0.6324349277377499 1.0 0.8923338846337773 3 P83731,Q9H061 2 +Negative regulation of lymphocyte activation 0.3825656870430667 0.4775712487902626 0.6329553985106762 1.0 0.8926186327465973 13 Q13951 1 +Protein o linked glycosylation 0.3825005009381735 0.4772733893170604 0.6331674574852595 1.0 0.8926186327465973 13 O60762,O60502 2 +Negative regulation of protein containing complex disassembly 0.3467613182137767 0.4764396375392911 0.6337612015073633 1.0 0.8928086180985032 21 Q6IBS0,Q12792,Q8WWK9,P35241,Q92974,Q9BPX3,P58546,P29372 8 +Ribonucleoside triphosphate biosynthetic process 0.3369793138093555 0.4751361872645674 0.6346899069404153 1.0 0.8928571095148512 29 O75947,P12268,P06733,Q9NRF8,Q9BZX2,P00846,P56385,P06576,Q9UJZ1 9 +Semaphorin plexin signaling pathway 0.4859055893097797 0.4745030766412991 0.6351412045274629 1.0 0.8928571095148512 5 Q9NWH9 1 +Clathrin dependent endocytosis 0.3818332130139386 0.4742276723082115 0.6353375621714386 1.0 0.8928571095148512 13 Q13432 1 +Positive regulation of cell matrix adhesion 0.4330874231968181 0.4738239476404296 0.6356254559357197 1.0 0.8928571095148512 9 P14923,P49593 2 +Negative regulation of protein localization to nucleus 0.4745698470386214 0.4735478327556709 0.6358223836072718 1.0 0.8928571095148512 6 O95602,Q96ST3 2 +Cardiac chamber development 0.3678565904328739 0.4732721879990956 0.6360190016640495 1.0 0.8928571095148512 14 O75844,Q96T37,P15924 3 +Positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator 0.6034788854261943 0.4729582008291242 0.6362430007061892 1.0 0.8928571095148512 3 P62081 1 +Response to nicotine 0.4853154685936404 0.4725345191691114 0.6365453087325719 1.0 0.8928571095148512 5 P09601 1 +Blood vessel morphogenesis 0.2985400677582279 0.4724821311113197 0.6365826931977745 1.0 0.8928571095148512 65 P20936,P31749,Q96PU8,P14923,P51608,Q9NZ08,P09601,P04792,Q96T37,P42785,O95470,Q9UII2,Q5JRA6,Q13043 14 +Barbed end actin filament capping 0.4324597727730464 0.4714076578860728 0.6373496484172589 1.0 0.8933032920137259 9 Q12792,Q6IBS0,P58546 3 +Epithelium development 0.275214477296942 0.4705506630610685 0.6379616469094809 1.0 0.8933032920137259 143 O75844,O95747,P31749,P42574,Q16822,Q9NWH9,P31751,P26038,P58107,P80723,Q96T37,P46100,Q9Y3B8,Q13043,O14773 15 +Intrinsic apoptotic signaling pathway 0.2891164350592131 0.469140551325838 0.6389691751871291 1.0 0.8933260938409643 78 O75915,P31749,O75489,Q969S3,P09601,P04792,Q9BVC6,O14745,P46379,P42574,P04179,Q9Y3B8,P49593 13 +Neuron projection regeneration 0.4436810971714134 0.4689848700648714 0.6390804507253145 1.0 0.8933260938409643 8 P00374,P07196 2 +L alpha amino acid transmembrane transport 0.4315846711497593 0.468045699634172 0.6397519092827681 1.0 0.8939015981461315 9 O60831,P08195,Q9Y619,O75915 4 +Spindle organization 0.2943036418883666 0.4669331553784043 0.640547703171334 1.0 0.8943870406509958 72 Q8WUX9,Q02241,Q9HBM1,O00139,O43633,Q8IZT6,Q9BV86,Q9BZD4,Q9H0H5,Q96CW5,P46100,Q00839,P51608,P16949,P14635,O43663 16 +Positive regulation of mapk cascade 0.3096316878456864 0.4660683076209266 0.6411666074643536 1.0 0.8948855147741944 40 O75116,O75915,O43318,Q15750,Q969S3,Q02952,Q9Y639,Q6IAA8,P36507,P04899,P29372 11 +Positive regulation of exocytosis 0.3654998948718166 0.4620590361284842 0.6440389850910484 1.0 0.8966840467177243 14 P20339 1 +Response to tumor necrosis factor 0.3285775293208412 0.4614549441711461 0.6444722395888198 1.0 0.8966940768540785 32 O95429,P31749,Q16539,Q02952,Q16822,Q8TCT8,P42574,Q9H6S0 8 +Protein localization to cell cell junction 0.4560332383853359 0.4601264870271788 0.6454254332101561 1.0 0.8974270392620405 7 Q9Y624,P15924 2 +Cytokinesis 0.3076296820046987 0.4591958310490323 0.6460935440707076 1.0 0.8979605188779327 53 Q8WUX9,Q02241,P20936,O75116,Q14141,O43633,Q53EZ4,Q8WWK9,Q7Z7K6,Q9NQW6,Q9H0H5,Q13432,P16949,P18583,O43663 15 +Neuron projection guidance 0.3641503432547568 0.4556763626217796 0.6486227219754963 1.0 0.900312778042756 14 Q9Y639 1 +Cellular response to abiotic stimulus 0.2999726528438263 0.4537753992060749 0.649990491779469 1.0 0.901392480802892 62 O95202,O75844,O95747,Q9H2U1,Q9Y376,P31751,Q9BVC6,P42574 8 +Negative regulation of cell growth 0.3394974599025235 0.4528381676818988 0.6506652776697277 1.0 0.9019225561906908 25 Q9P265 1 +Import across plasma membrane 0.3770656766673664 0.4526493434046614 0.6508012616415564 1.0 0.9019225561906908 13 O14745,O75915,P31751,P31749 4 +Positive regulation of leukocyte cell cell adhesion 0.3379347903270482 0.4519823129062584 0.6512817243416025 1.0 0.9021923667162962 26 P31749,Q96EY1 2 +Positive regulation of dna templated transcription initiation 0.4381289443549826 0.4486162326068481 0.6537085218854128 1.0 0.9041655218366914 8 Q9H2U1,O75448 2 +Nucleotide excision repair 0.3585390890301334 0.4479370241716094 0.6541986470118148 1.0 0.9046452600158998 16 P35244 1 +Neuron development 0.2720625699298681 0.4474500196052645 0.6545501672879563 1.0 0.9049331631828677 145 P55145,Q9UQB8,Q8TEY7,Q7KZI7,Q9H2U1,P07196,Q08209,Q9P265,Q6IBS0,Q12756,Q96ST3,Q9Y639,Q9H4M9,Q96G23,P31749,Q14195,P00374,P04179,O14745,P42574,P51608 21 +Positive regulation of endothelial cell proliferation 0.4136841687264672 0.445542482559892 0.655927766082629 1.0 0.9055543710448746 10 P09601,P31749 2 +Regulation of carbohydrate catabolic process 0.388063897339667 0.4433020569208208 0.657547268201303 1.0 0.9055543710448746 12 O15294,P40763 2 +Positive regulation of viral genome replication 0.3575469192174496 0.4431413089942389 0.6576635275408003 1.0 0.9055543710448746 16 O95793 1 +Midbrain development 0.3484526706115151 0.4430234471212204 0.6577487752309854 1.0 0.9055543710448746 19 O75489,P80723,O14949 3 +Cellular response to lipoprotein particle stimulus 0.4761750293547735 0.4424228090430492 0.6581832766910176 1.0 0.9057910220198528 5 P31749 1 +Inner ear receptor cell stereocilium organization 0.5759559100901201 0.4400672061952089 0.6598884326257017 1.0 0.9064229538903176 4 Q14651,O14745 2 +L proline biosynthetic process 0.5757480538563855 0.4394626659137944 0.6603263281440501 1.0 0.9065667397046168 4 P32322 1 +Regulation of keratinocyte proliferation 0.4749590992661234 0.438472387603927 0.6610438822790707 1.0 0.9068165503609772 5 Q9Y3B8 1 +Keratinocyte proliferation 0.4749590992661234 0.438472387603927 0.6610438822790707 1.0 0.9068165503609772 5 Q9Y3B8 1 +Maintenance of protein localization in organelle 0.3601455732319732 0.4369057678520578 0.6621796887824816 1.0 0.9076918807555784 14 P31749 1 +Selective autophagy 0.3374783624618083 0.4348689300266783 0.6636575680554446 1.0 0.9087690055740788 24 P53365,Q96HY6,Q9Y4P1 3 +Response to interleukin 1 0.372009959618199 0.4301294620730023 0.6671014695790409 1.0 0.912495381048974 13 Q9H6S0,Q02952,O43318 3 +Morphogenesis of a branching structure 0.383917485319128 0.425741449458878 0.6702962553426657 1.0 0.916388494263236 12 Q96T37,Q9NWH9 2 +Negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway 0.4315443001083028 0.4248804502715752 0.6709238267622153 1.0 0.9167510101521136 8 P04792,P31749 2 +Cytokinetic process 0.3570386790462592 0.4225241592161095 0.6726424704603433 1.0 0.9170134629734716 14 Q8WUX9,P50995,O43633,Q53EZ4,Q15149,Q9NQW6,O95235,Q9H0H5,Q8WUM4,P35579 10 +Positive regulation of i kappab kinase nf kappab signaling 0.3199943825571208 0.4222992277460006 0.6728066217671136 1.0 0.9170134629734716 33 Q8TB61,O43318,Q9H2U1,Q8IUH4,P09601 5 +Phosphatidylinositol dephosphorylation 0.5695491202781062 0.4215873545466738 0.6733262379162468 1.0 0.9172474158861432 4 Q01968 1 +Regulation of myelination 0.407495762830415 0.4214851231172399 0.6734008723072118 1.0 0.9172474158861432 10 P31749 1 +Cell cell adhesion via plasma membrane adhesion molecules 0.4298393302119068 0.4188118486587771 0.6753536447668864 1.0 0.918653068533902 8 Q9Y639 1 +Regulation of canonical wnt signaling pathway 0.3291498809391748 0.418767507067592 0.6753860538698722 1.0 0.918653068533902 28 Q8IZT6,Q16539,P14923,Q13283,O14745,Q13043,P52294 7 +Regulation of microtubule polymerization 0.3464561106698356 0.4161915999592971 0.6772698059541642 1.0 0.9201230715244084 18 P51608,P16949,Q9NWH9 3 +Membrane lipid biosynthetic process 0.3394813944654722 0.4152975941678434 0.6779240622001186 1.0 0.9201230715244084 20 Q06136,Q92643,O60762,O95470 4 +Reticulophagy 0.4672993704148704 0.4138988996361252 0.678948149780765 1.0 0.9206308256775956 5 Q96HY6 1 +Acylglycerol homeostasis 0.5668119259577709 0.4137909637595846 0.6790272022775679 1.0 0.9206308256775956 4 Q8WTV0 1 +Inner ear receptor cell development 0.4562851679148563 0.4121442836143457 0.6802336721713262 1.0 0.9218706602467812 6 Q14651,O14745,P54802 3 +Meiosis i cell cycle process 0.3482793150930017 0.4110263450648083 0.6810532169647792 1.0 0.9222804540543348 17 P46379,P46100 2 +Regulation of dna templated transcription initiation 0.4041438861398418 0.4086556490000492 0.6827923856663172 1.0 0.922961062534174 10 Q9H2U1,O75448 2 +Regulation of nitric oxide metabolic process 0.4039432555835396 0.4078923327998173 0.6833527219801157 1.0 0.9233231514193132 10 O75116,P31749,Q08722,P04179,P50570 5 +Myelin maintenance 0.5644652508031556 0.4071550779165523 0.6838940928196726 1.0 0.9237313835888205 4 P31749 1 +Calcineurin mediated signaling 0.4650803115594252 0.4068832320888029 0.6840937519260888 1.0 0.9237313835888205 5 Q08209,Q9UHD1 2 +Inositol phosphate mediated signaling 0.4650803115594252 0.4068832320888029 0.6840937519260888 1.0 0.9237313835888205 5 Q08209,Q9UHD1 2 +Vesicle mediated transport between endosomal compartments 0.3530806391400276 0.4044404613038436 0.6858888517549344 1.0 0.9248531037540014 14 P26038,P20339 2 +Positive regulation of chromosome condensation 0.4642777286097577 0.4043575551255557 0.6859498075514712 1.0 0.9248531037540014 5 O95347,Q9BPX3 2 +Homologous chromosome segregation 0.4143399409781759 0.4035439426256258 0.6865481149874679 1.0 0.9252396021490668 9 P46379 1 +Exocrine system development 0.5792704947634564 0.4032156379558128 0.6867895965355264 1.0 0.9252396021490668 3 Q12948,P60953 2 +Neuron recognition 0.4534105423238289 0.4027836854473743 0.6871073640170677 1.0 0.925425745819916 6 Q9Y639 1 +Response to dopamine 0.390476395287877 0.4019463332410105 0.6877235227419534 1.0 0.9258606231540925 11 Q96ST3,O14745 2 +Cellular response to oxygen levels 0.3139007919247253 0.4006824220293155 0.6886539541004866 1.0 0.9265528292893532 34 Q9NZM5,P09601,P31749 3 +Pancreas development 0.4135131229786827 0.4005396734926155 0.6887590684329692 1.0 0.9265528292893532 9 P31749 1 +Gpi anchor metabolic process 0.4629597694872999 0.4002236775108658 0.6889917766539491 1.0 0.9265802082626272 5 Q92643 1 +Antimicrobial humoral response 0.452475712401167 0.3997577283079333 0.6893349682842738 1.0 0.92683322305672 6 P39019 1 +Hydrogen peroxide metabolic process 0.4128293495556906 0.3980615924757596 0.6905847847484452 1.0 0.9272130280702154 9 P04179,Q15067 2 +Nuclear ncrna surveillance 0.4518671339735256 0.3977926456062227 0.6907830388398417 1.0 0.9272130280702154 6 Q06265 1 +Protein targeting to vacuole 0.3644961097007575 0.397392987147747 0.6910776861099832 1.0 0.9272130280702154 13 Q96RL7,P20645 2 +Negative regulation of proteasomal protein catabolic process 0.332148086839984 0.3970917584269577 0.6912997972169994 1.0 0.92721425063353 21 Q9NZM5,P46379,Q04323,P60520,Q96HY6 5 +Microtubule nucleation 0.3887762932544557 0.3952605633934027 0.6926506006241615 1.0 0.92721425063353 11 P51608,Q96CW5,Q96S59 3 +Non lytic viral release 0.4612882439906812 0.3950054414684836 0.6928388721426311 1.0 0.92721425063353 5 Q8WUX9 1 +Response to monosaccharide 0.3236892156182941 0.3943253942326579 0.6933408171141882 1.0 0.92721425063353 29 Q96ST3,Q16822,Q9NWS0,Q08209,P42574,P04179 6 +Regulation of actomyosin structure organization 0.3316024193213383 0.3942158677375017 0.6934216715514037 1.0 0.92721425063353 21 O75116,Q9NWH9,Q08722,P16949,Q9Y624,O95429,P49593 7 +Negative regulation of ubiquitin dependent protein catabolic process 0.3308998722588187 0.3942101601731497 0.693425885074221 1.0 0.92721425063353 23 P19784,Q9NZM5,P46379,Q04323,Q96HY6,O15294 6 +Response to lipid 0.2791509733691031 0.3932876696121863 0.6941070242515401 1.0 0.92721425063353 122 Q6IBS0,Q969T9,O95747,O15173,P31749,P61353,Q86U42,Q16822,P07196,Q9P253,P26038,P40763,Q8WTV0,P42574,Q96HY6,P04179,Q9UER7,O00767 18 +Sterol homeostasis 0.3882303240475624 0.3931222919821466 0.6942291602412531 1.0 0.92721425063353 11 Q9H4M9,O95486,Q9UKM9,Q6IAA8,Q8WTV0,P35610 6 +Maintenance of location 0.2919338170177776 0.3930137728029871 0.6943093089951424 1.0 0.92721425063353 63 O95202,O75832,O95674,Q6IBS0,Q8IZT6,P31749,Q96RL7,Q8WTV0,O94901 9 +Cdp diacylglycerol metabolic process 0.4602426818544057 0.3917554947834986 0.6952388818224515 1.0 0.9282593148291308 5 O95674 1 +Establishment of cell polarity 0.3094166047316485 0.3910495858555855 0.6957605840017758 1.0 0.9284830608647046 35 Q7KZI7 1 +Cerebellar purkinje cell layer morphogenesis 0.4729241877256265 0.3908718008682552 0.6958919987577881 1.0 0.9284830608647046 2 P04062 1 +Focal adhesion assembly 0.3380615638602275 0.3902286909238312 0.6963674477392632 1.0 0.9285879757182064 19 P49593 1 +Receptor localization to synapse 0.3868912557087355 0.3878961563730485 0.6980928826426707 1.0 0.9302993796973033 11 Q4V328,Q9Y639 2 +Intermediate filament based process 0.3744618100293477 0.3866385607923608 0.6990238065068688 1.0 0.930920229649953 12 P15924,P58107,P07196,O75190 4 +Positive regulation of glucose import 0.4585774320897892 0.3866020362249195 0.6990508502625334 1.0 0.930920229649953 5 P31751,P31749 2 +Response to manganese ion 0.572969070374759 0.3858372742111975 0.6996171879423967 1.0 0.931347865205206 3 P04179 1 +Cellular modified amino acid catabolic process 0.434074320948268 0.3849488301299241 0.7002753271209605 1.0 0.9318310675325068 7 Q8N2K0 1 +Protein ufmylation 0.5561044265162844 0.3838835122683102 0.7010647871513576 1.0 0.9322921369152636 4 Q96HY6 1 +Positive regulation of mitotic cell cycle 0.2975983021014993 0.3836130069067663 0.7012652981698562 1.0 0.9323455493528832 38 Q96ST3,P51608,P14635,P31749 4 +Negative regulation of organelle assembly 0.4332764189546103 0.3823148803457466 0.7022278186014135 1.0 0.9326730149312596 7 Q96PK6,Q96KQ7 2 +Activation of gtpase activity 0.3608053401794026 0.381651606520938 0.7027198000188051 1.0 0.9327959746907676 13 P31751 1 +Regulation of cardiac conduction 0.5551875977977626 0.3813676321571486 0.7029304752618697 1.0 0.9327959746907676 4 P17612,Q6PI78 2 +Actin filament based process 0.2613875821573713 0.3796551670984395 0.7042014040564704 1.0 0.9327959746907676 152 Q9UQB8,P60983,Q01518,Q8WX93,P84095,Q07157,P78310,P53367,P52565,Q15942,Q68EM7,P58546,P35609,P52306,P10644,Q8N5W9,Q6IBS0,O15145,Q12792,Q9NQW6,Q8NE86,O95429,Q6WCQ1,P20936,Q96JJ3,Q08722,Q9NWH9,O75190,Q9H0H5,Q92974,Q9BPX3,P53365,Q4VCS5,P49593,O75116,Q14195,P14923,Q9Y490,Q15149,Q9NSV4,O60610,O14745,Q9Y624,P16949,P15924 45 +Import into cell 0.3325363233950654 0.3796219754183047 0.7042260458806968 1.0 0.9327959746907676 20 O75915,P31749,P31751,Q99808,P08195 5 +Attachment of mitotic spindle microtubules to kinetochore 0.446181650283067 0.3796215193836623 0.7042263844473866 1.0 0.9327959746907676 6 Q9BZD4,Q99661 2 +Positive regulation of glucose transmembrane transport 0.4456753685484906 0.378020069481611 0.7054156850035254 1.0 0.9327959746907676 6 P31751,P31749 2 +Nucleotide transmembrane transport 0.4181062290877632 0.3779599944758048 0.7054603131297617 1.0 0.9327959746907676 8 O15439,Q8TB61 2 +Positive regulation of proteolysis 0.2754487810400186 0.3771109827461905 0.7060911296859234 1.0 0.9327959746907676 82 O75832,O00487,O75915,P31749,Q92542,Q9NZM5,Q9UNE7,P46379,P40763,O14737,Q96HY6,Q9UII2,O15294,P62333,P49593,Q14997 16 +Peripheral nervous system development 0.4176986891985226 0.3765706482106242 0.7064927039949811 1.0 0.9327959746907676 8 P31751,P31749 2 +Regulation of exit from mitosis 0.4449573725305973 0.3757536781445509 0.7071000277951878 1.0 0.9327959746907676 6 Q9NQW6 1 +Neuron differentiation 0.2607813495262934 0.3725144186529602 0.7095098786990497 1.0 0.9330286504290908 174 P55145,Q9UQB8,Q8TEY7,Q7KZI7,Q9H2U1,P07196,Q08209,P58546,Q9P265,Q6IBS0,Q12756,Q96ST3,Q9Y639,P28370,Q9H4M9,Q96G23,Q8IZT6,P31749,Q9NWH9,P40763,Q14195,P00374,P04179,O14745,P42574,P51608 26 +Autophagosome organization 0.326694381128326 0.3717295108009386 0.7100942505853989 1.0 0.9330370019745904 23 P53365,P20339,Q9Y4P1 3 +Response to endogenous stimulus 0.2705290996534553 0.3715932321978371 0.7101957287757177 1.0 0.9330370019745904 248 Q9UQB8,Q16822,P07196,P33527,P35609,P04899,Q9UER7,O75844,Q15392,Q969T9,Q96ST3,Q9Y376,Q9P253,Q9Y639,O43237,Q96HY6,O95429,Q5JRA6,O43318,P31749,P31751,P42785,P43490,O15173,P61353,P14923,P09601,P42574,O14737,Q9UNE7 30 +Response to reactive oxygen species 0.3138930100200655 0.368284643754445 0.7126610016257358 1.0 0.9345257662024706 32 P00374,P09601,Q9NWH9,P31749 4 +Epithelial cell apoptotic process 0.3697356113948714 0.3676142168080714 0.7131609125756415 1.0 0.9347930251199088 12 Q13043,P09601 2 +Sphingolipid biosynthetic process 0.3446470177993435 0.366846117777896 0.7137338051951125 1.0 0.93515568499729 14 Q06136,O95470 2 +Positive regulation of megakaryocyte differentiation 0.465703971119127 0.3666071704030188 0.7139120588865562 1.0 0.9351951742343808 2 Q9GZP4 1 +Rrna 5 end processing 0.5648646001961245 0.3639917931271172 0.715864137783262 1.0 0.9365548347839464 3 P78316 1 +Positive regulation of peptidyl serine phosphorylation 0.3565706195760482 0.3638788460390194 0.7159484817812654 1.0 0.9365548347839464 13 O95429,Q13043,P02786,P31749 4 +Negative regulation of growth 0.3209361039068019 0.3636600670241894 0.7161118663423469 1.0 0.9365548347839464 27 O75489,Q9P265 2 +Positive regulation of peptidase activity 0.2956581667292707 0.3634282934286396 0.716284969460196 1.0 0.9365548347839464 40 O75116,O75915,O00487,Q92542,P40763,P49593,O14737,Q96HY6,Q06323,Q14997 10 +Mitochondrial dna replication 0.4408377998498051 0.3628589025076159 0.7167102883553764 1.0 0.9366388022692654 6 Q96EY1 1 +Calcium ion transport 0.2965599223339002 0.361997690016192 0.7173537566499901 1.0 0.9366388022692654 49 P04899,O75844 2 +Positive regulation of protein polyubiquitination 0.5476632872298682 0.3609973735264407 0.7181014104951666 1.0 0.9369895238409758 4 P61088 1 +Polyol catabolic process 0.4259615567912217 0.3585114469875148 0.7199606029847678 1.0 0.9376731885877044 7 Q9NX62,Q01968 2 +Fc receptor signaling pathway 0.562666294614293 0.3581671547466521 0.7202182256431422 1.0 0.9376731885877044 3 O43318 1 +Platelet aggregation 0.4015182012791887 0.3579425502362132 0.7203863070003078 1.0 0.9376731885877044 9 P04792,Q9Y624 2 +Negative regulation of molecular function 0.2640295254577534 0.3577302073337413 0.7205452248883155 1.0 0.9376731885877044 189 O75832,Q8TEY7,O95747,P30533,Q08209,P35609,P04899,Q15392,P62841,Q96ST3,Q9Y376,Q9UBB9,P04792,Q13217,Q7L2J0,O95429,P31749,O43768,Q9NWH9,O75190,Q15070,Q9UII2,P49593,Q9NVN8,Q7Z5K2,P09601,Q9NWS0,P16949,O14745,Q04323,P42574,Q9Y3B8,Q9UNE7 33 +Leukocyte cell cell adhesion 0.2947793716921223 0.357222814138706 0.7209250079296337 1.0 0.9376731885877044 40 P31749,Q13951,P26038,P42574,Q96EY1 5 +Regulation of transcription by rna polymerase iii 0.3902733463728712 0.3571706476149555 0.720964058398252 1.0 0.9376731885877044 10 Q9H2U1,P35659 2 +Regulation of inflammatory response 0.3140917436416873 0.357126200283175 0.7209973310596793 1.0 0.9376731885877044 31 P33527 1 +Learning 0.35474418720695 0.3563115342134595 0.7216072723742779 1.0 0.9376731885877044 13 P51608,Q9Y639 2 +Neurotransmitter reuptake 0.5455453167526629 0.3553542936451104 0.722324185607859 1.0 0.937693608217111 4 Q99808 1 +Fatty acid beta oxidation using acyl coa oxidase 0.5451664319336401 0.3543490793777882 0.7230772906753518 1.0 0.9377547376197618 4 O15254 1 +Protein depalmitoylation 0.5451331244213822 0.3542607740249434 0.7231434617470098 1.0 0.9377547376197618 4 Q8N2K0 1 +Lipoprotein catabolic process 0.5451331244213822 0.3542607740249434 0.7231434617470098 1.0 0.9377547376197618 4 Q8N2K0 1 +Oogenesis 0.3540489616424982 0.3534469066962527 0.723753425612734 1.0 0.9383530039669 13 Q8IZT6 1 +Cardiac muscle cell action potential involved in contraction 0.4377133602593838 0.3532048543020849 0.7239348689228309 1.0 0.9383955578687648 6 P14923 1 +Regulation of atp dependent activity 0.3176159178628338 0.3523565796375455 0.7245708609225372 1.0 0.9386102182951604 28 Q04837,Q5JTV8,Q15070,Q9UII2 4 +Ion homeostasis 0.2689040033177734 0.3519926856262053 0.7248437479263861 1.0 0.9386102182951604 88 Q8TAD4,O75027,P30519,Q9Y639,P09601,Q8NE86,Q96A33,P04899,Q8NE01 9 +Regulation of heart rate 0.409804205662495 0.3500696262402609 0.7262864451363822 1.0 0.9389463578625776 8 P14923 1 +Positive regulation of epithelial cell proliferation involved in lung morphogenesis 0.460649819494578 0.3500608897521998 0.7262930015522377 1.0 0.9389463578625776 2 P60953 1 +Regulation of epithelial cell proliferation involved in lung morphogenesis 0.460649819494578 0.3500608897521998 0.7262930015522377 1.0 0.9389463578625776 2 P60953 1 +Regulation of cell death 0.2582766502970901 0.3482130577182215 0.7276801820768537 1.0 0.9397184804263198 304 O75832,O95747,Q9NY61,Q969S3,Q02952,P07196,Q9NVI7,Q86XP3,P52565,P30533,P35609,P04899,Q9UER7,Q9NS69,Q15392,O75915,Q96ST3,P04792,Q13217,Q9UGN5,Q96TA2,Q96HY6,O95429,Q96EY1,P20936,P31749,O75489,Q9NWH9,P31751,O75190,Q9NZM5,Q13043,O95140,Q8WUX9,Q04760,P13051,Q9Y3A2,P09601,Q9NWS0,Q9Y3E5,P04179,Q9BVC6,O14745,O15294,P46379,P42574,O14737,P51608,Q9Y3B8 49 +Nucleotide transport 0.364585182317131 0.3473002315701878 0.7283657768332017 1.0 0.9398940353412704 12 O15439,Q8TB61,Q9H2D1 3 +Ncrna transcription 0.3201840829159006 0.3455203851688917 0.7297031876914153 1.0 0.9405926405800972 25 Q9H9Y6,Q9NZM5,P46100,Q7L2J0,Q9P0M6 5 +Regulation of cell division 0.3190122295486118 0.3453374541119626 0.729840692298227 1.0 0.9405926405800972 26 Q9Y3B8,Q7Z7K6,Q8IZT6 3 +Positive regulation of signaling 0.2680783303648961 0.344483135733807 0.7304829765704093 1.0 0.9408229959525802 217 Q9UQB8,Q9H2U1,Q8IUH4,Q969S3,Q16822,P04899,Q969T9,O75915,P62841,O95793,Q9Y639,Q8NE86,O43318,Q8IZT6,Q9NWH9,Q01469,Q13043,Q8TB61,P56545,P14923,P09601,P51608 22 +Positive regulation of cytokinesis 0.3861696571839051 0.3424634753346259 0.7320021264971652 1.0 0.9418914666197477 10 Q9H0H5,Q7Z7K6 2 +Positive regulation of cell division 0.3628332786992377 0.3404931504547231 0.7334851801308668 1.0 0.9427637489305664 12 Q9H0H5,Q7Z7K6 2 +Heterotypic cell cell adhesion 0.3963469353545575 0.3401743628056348 0.7337252236688001 1.0 0.9427637489305664 9 P14923,P78310 2 +Protein dna covalent cross linking repair 0.457400722021654 0.3396207335515729 0.734142162161191 1.0 0.9431075507397272 2 P55072 1 +Interleukin 8 production 0.3948873436409603 0.3352273026976866 0.7374536278187047 1.0 0.9458221015736952 9 O95999,P62820,P40763 3 +Regulation of actin filament bundle assembly 0.3193905138213778 0.3337355354590502 0.7385791320473531 1.0 0.9465600463962373 23 O75116,Q07157,Q9NWH9,Q08722,P16949,Q9Y624,O95429,P49593 8 +Cellular amino acid catabolic process 0.2902311135688269 0.3322812660531581 0.7396768845601507 1.0 0.9465600463962373 38 Q9HCC0 1 +Pallium development 0.3003287429879918 0.3320201514597837 0.7398740426639474 1.0 0.9465600463962373 35 Q96P11,P07196,Q8IZT6,P42574 4 +Protein heterooligomerization 0.4040469639612317 0.3312539052329717 0.7404527058717931 1.0 0.9467197856713446 8 Q16630 1 +Regulation of cell differentiation 0.2617592249011041 0.3311216684198166 0.7405525849589438 1.0 0.9467197856713446 187 Q9UQB8,O95747,Q9H2U1,P07196,Q08209,Q9P265,Q8N5W9,Q6IBS0,Q14004,Q96ST3,Q9Y639,Q8N4Q0,Q96T37,Q9UGN5,Q9P0M6,Q96G23,Q8IZT6,P31749,P39019,Q13043,Q13951,P51608,Q9Y3B8 23 +Microtubule cytoskeleton organization 0.2667911084830423 0.3306383940650864 0.7409176415391223 1.0 0.9468011754913458 140 P68371,Q02241,Q8TEY7,Q7KZI7,P07196,Q8IWJ2,P14635,Q8WWK9,Q99661,O43237,Q9BZD4,Q9HBM1,Q8IZT6,Q9NWH9,Q9H0H5,Q00839,O43663,Q8WUX9,O75116,O00139,A0AVF1,O43633,Q9BV86,Q96S59,Q9BSJ2,Q96CW5,P46100,O94901,P51608,P16949,P18583,P29372 32 +Stress fiber assembly 0.3171408431698067 0.3294884752435608 0.7417865035237161 1.0 0.9468011754913458 25 O75116,Q07157,Q9NWH9,Q08722,P16949,Q9Y624,O95429,P49593 8 +Angiotensin activated signaling pathway 0.5514084533515919 0.329036920569312 0.7421277817774414 1.0 0.9468011754913458 3 P35609 1 +Regulation of plasminogen activation 0.5511014806789487 0.328259335231601 0.7427155879329483 1.0 0.9468011754913458 3 P06733,P07355 2 +Positive regulation of plasminogen activation 0.5511014806789487 0.328259335231601 0.7427155879329483 1.0 0.9468011754913458 3 P06733,P07355 2 +Regulation of peptidyl serine phosphorylation 0.3219448763969355 0.3273148394917468 0.7434297697697538 1.0 0.9469468562288128 20 Q13043,P49593,P31749 3 +Mitochondrial calcium ion homeostasis 0.3919514159970594 0.3253691553837765 0.7449016970225981 1.0 0.9478297379423342 9 Q8NE86 1 +Dna replication 0.2736602775844132 0.3250097239290323 0.7451737122498807 1.0 0.9478297379423342 108 P18858,O75844,Q7Z5K2,Q96ST3,O94761,Q04837,P35244,P17096,Q07864,Q96EY1 10 +Positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay 0.533289031254207 0.3235114547944839 0.7463079338834682 1.0 0.9484683280383104 4 Q9H2U1,P11940 2 +Regulation of lipid localization 0.3269141339695272 0.3232797478778262 0.7464833901065471 1.0 0.9484683280383104 18 Q9H4M9,P31749,P31751,Q6IAA8,Q8WTV0 5 +Alpha amino acid catabolic process 0.3038515062086874 0.3212153331284123 0.74804721319583 1.0 0.9485680006965918 33 Q9HCC0 1 +Positive regulation of cellular component organization 0.2657015910112922 0.3210623457148099 0.7481631446638235 1.0 0.9485680006965918 210 Q9UQB8,Q7KZI7,Q9H2U1,P07196,Q08209,P35609,Q71SY5,Q6IBS0,O75027,Q96ST3,Q9Y639,Q9NQW6,Q8NE86,P26038,O95429,Q9NWH9,P31751,Q04837,Q9UII2,P49593,Q9NVN8,Q14195,P46100,O14737,P51608,Q9UNE7 26 +Regulation of autophagy 0.271812330238686 0.3193748671011483 0.7494422668277521 1.0 0.949243424824559 80 O75844,P21281,Q8TEY7,O43318,P31749,P09601,Q9NWH9,P04792,Q96A65 9 +Multicellular organism growth 0.3161573171624964 0.3173654433768382 0.7509663251030743 1.0 0.9505683577031688 23 O75844,Q14318,Q15149,P40763,O95470,Q9C0B1,P46100,P18074 8 +Negative regulation of extrinsic apoptotic signaling pathway 0.3255703788149187 0.3172017542054516 0.7510905189390416 1.0 0.9505683577031688 18 P31749 1 +Monocarboxylic acid catabolic process 0.2903558468247394 0.3167560779139549 0.7514286940049857 1.0 0.9508057663221404 45 Q15067,P31749,O15254,Q16822,P31751,Q8NCC3 6 +Cellular response to unfolded protein 0.3049264760797808 0.3146979618712188 0.752990991880987 1.0 0.9520177306072456 32 P57088,O76024,Q9BUN8,Q9NRK6,Q96HY6,Q9UER7,Q9UNE7 7 +Regulation of rho protein signal transduction 0.3559582807427022 0.3143026426110611 0.7532911913388975 1.0 0.9520177306072456 12 Q9NWH9,P16949,P52565,Q9Y624 4 +Cellular glucan metabolic process 0.3305750459118029 0.3129759331943471 0.7542989467913632 1.0 0.952211204838762 15 Q16851,P31751,P31749 3 +Nuclear envelope organization 0.3138847666385166 0.3126263278355415 0.7545645733323942 1.0 0.952211204838762 25 Q8WUX9,O75844,O43633,Q99986,O94901,Q5JTV8 6 +Endosome organization 0.3218748997234383 0.3126115879224327 0.7545757732042049 1.0 0.952211204838762 19 Q8WUX9,Q92783,Q6IAA8,Q9P253 4 +Negative regulation of keratinocyte proliferation 0.5444543484559501 0.3116452699448935 0.7553101259428272 1.0 0.952211204838762 3 Q9Y3B8 1 +Carbohydrate biosynthetic process 0.2892100524663803 0.3115267065281631 0.7554002433831797 1.0 0.952211204838762 43 P31749,Q16822,P31751,O15294,Q13043,Q9UBX3 6 +Positive regulation of carbohydrate metabolic process 0.4107569907034383 0.3111239141731199 0.7557064218319665 1.0 0.952211204838762 7 P31749 1 +Positive regulation of glucose metabolic process 0.4230439120801582 0.3093985277611329 0.7570183901665231 1.0 0.9527251489279076 6 P31749 1 +Positive regulation of cellular carbohydrate metabolic process 0.4230439120801582 0.3093985277611329 0.7570183901665231 1.0 0.9527251489279076 6 P31749 1 +Vesicle mediated transport to the plasma membrane 0.2881717001760305 0.3088235748985934 0.7574557349547633 1.0 0.9527251489279076 41 Q96KP1,Q9H4M9,Q4V328,Q8TAG9,P35609,Q8IWJ2,Q96A65,O75436 8 +Negative regulation of phosphorus metabolic process 0.2726437797675453 0.3088017694880809 0.7574723230310574 1.0 0.9527251489279076 78 P31749,O43768,Q13217,P04899,Q9Y3B8,P49593 6 +Negative regulation of actin filament depolymerization 0.3308746971634796 0.3084395578869617 0.7577478853648367 1.0 0.9528614474474932 14 Q6IBS0,Q12792,P35241,Q9BPX3,P58546 5 +Protein heterotetramerization 0.4098073508703576 0.308262611531358 0.7578825133166474 1.0 0.9528614474474932 7 Q16630 1 +Polarized epithelial cell differentiation 0.3965840739607425 0.3075358652659261 0.7584355282788788 1.0 0.9531771348632248 8 P26038 1 +Cell cycle dna replication initiation 0.422085743870272 0.3066277395456713 0.7591267369946246 1.0 0.953666179344222 6 Q9BRX5,P33991 2 +Cellular response to carbohydrate stimulus 0.3174665965959484 0.3060222764344155 0.7595876847771679 1.0 0.9538683940613278 20 Q08209,Q96ST3,Q16822,Q9NWS0 4 +Cortical actin cytoskeleton organization 0.3250906723564073 0.304798975802414 0.7605192616255416 1.0 0.9545444060358816 17 O75116,P27797,Q9Y490,Q15149,Q9NQW6,Q9H0H5,Q14651 7 +Platelet derived growth factor receptor signaling pathway 0.4081300052063592 0.303237986375106 0.7617085020508618 1.0 0.9555786771208308 7 O95470 1 +Cellular macromolecule localization 0.261443054395027 0.2996347258975489 0.7644557930664324 1.0 0.9563184076475169 482 O60830,Q99595,Q9NS69,O14773,Q8N4V1,P20645,Q76FK4,Q96A65,Q96EY1,P31749,Q15070,Q9BUN8,Q9NZM5,P53365,Q9UII2,P20339,Q9Y4P1,Q9Y282,Q14789,Q9UI26,O14737,Q9Y3B8,Q9C0E2,Q9Y5L4,P35609,Q5JTV8,Q92783,O75915,Q96ST3,P04792,P26038,Q96HY6,Q9Y584,O14925,Q10567,P31751,O75190,Q96A33,P60520,O94973,Q13043,Q9NVN8,Q8WUX9,Q7Z5K2,A0AVF1,P14923,Q96RL7,P46379,P46100,O94901,Q9Y276,Q9H2U1,Q08209,Q8IWJ2,Q92643,Q6IBS0,Q4V328,Q14141,Q13596,Q9P253,Q7L2J0,O95429,Q5JRA6,Q5SRE5,Q9P0M6,Q9H4M9,P50748,P40763,Q9NPA0,O95140,O75436,Q99797,Q9NWS0,Q8TAG9,O14745,O43592,Q8NBU5,P53367,P08240,Q6IAA8,Q9HD45,P52294,P57105,O75608 84 +Positive regulation of intrinsic apoptotic signaling pathway in response to dna damage 0.4444043321299571 0.2994599463365124 0.7645891287482058 1.0 0.9563184076475169 2 P61254 1 +Positive regulation of activated t cell proliferation 0.444404332129957 0.2994599463365118 0.7645891287482063 1.0 0.9563184076475169 2 P09429 1 +Lipid storage 0.3257322892045067 0.2992674971604934 0.7647359522834547 1.0 0.9563184076475169 16 Q8WTV0 1 +Response to nitrogen compound 0.264411391383619 0.2992119954961258 0.7647782972450428 1.0 0.9563184076475169 211 Q9UQB8,Q9H2U1,Q16822,P07196,Q08209,O76024,P33527,Q6IAA8,P35609,P04899,Q9UER7,P49721,Q96ST3,Q5JRA6,P31749,P31751,Q8TCJ2,Q9BUN8,Q96A33,P40763,P43490,Q9NYU2,P14923,P00374,O14745,P46379,P46100,P42574,Q04323,O15294,Q9UNE7 31 +Peptidyl serine modification 0.2865521007658252 0.2980955025090916 0.7656302740985426 1.0 0.9563184076475169 54 P31749,Q7KZI7,Q9Y376,P31751,Q99986,Q9UGN5,P36507,O95429,Q13043,P49593 10 +Maintenance of location in cell 0.2859823466868738 0.296926396024209 0.7665227033682429 1.0 0.9570544490937484 40 O95202,Q8IZT6,P31749,Q96RL7,O94901 5 +Response to carbohydrate 0.2994240792659052 0.2950656853762659 0.7679437024049562 1.0 0.9580708431110244 33 Q96ST3,Q16822,Q9NWS0,Q08209,P42574,P04179 6 +Meiotic cell cycle 0.2870040136467495 0.2947320143641019 0.7681986049998364 1.0 0.9581995242925656 51 Q5VUA4,P42695,Q8IZT6,Q9Y2W6,Q9BZD4,Q96CW5,P46379,P46100,O94901 9 +Nuclear chromosome segregation 0.2672695765168305 0.2934720826458827 0.7691613353727975 1.0 0.958497842166975 96 Q02241,Q53EZ4,P14635,Q53HL2,Q99661,Q9BZD4,Q9NTI5,Q9HBM1,P50748,Q9H0H5,Q9BPX3,Q00839,O43663,Q8WUX9,P42695,Q7Z5K2,P46379,P46100,O94901 19 +Cellular response to interleukin 1 0.3716605133383932 0.2925481852286092 0.7698675238669619 1.0 0.958497842166975 10 Q02952,O43318 2 +Positive regulation of cell cycle g1 s phase transition 0.3174329757312858 0.2924065538994878 0.7699757978125072 1.0 0.958497842166975 19 P31749,P35241,Q04637,Q7L2J0,Q96HY6,P31350 6 +Odontoblast differentiation 0.4418772563176826 0.2919575626571626 0.7703190710856953 1.0 0.958497842166975 2 P07437 1 +Regulation of meiotic cell cycle 0.404316789814297 0.2919560369536595 0.7703202376289331 1.0 0.958497842166975 7 Q8IZT6 1 +Endothelin receptor signaling pathway 0.4415162454873576 0.2908941461789053 0.77113227848987 1.0 0.958497842166975 2 P60953 1 +Positive regulation of protein maturation 0.4253704372966922 0.2901167583464695 0.7717269155771329 1.0 0.958497842166975 5 P60903,P06733,P07355,P35579 4 +Leukocyte degranulation 0.3908930308365745 0.2899794042487025 0.7718319939992289 1.0 0.958497842166975 8 P09601 1 +Phosphatidylinositol metabolic process 0.3192740769756956 0.2893028286384135 0.7723496478876959 1.0 0.958497842166975 18 Q92643,Q01968,Q6UWP7,O60762,Q9NX62 5 +Action potential 0.3247723729462933 0.289043353465812 0.7725482014959697 1.0 0.958497842166975 15 P14923,P78310,P15924 3 +Negative regulation of hematopoietic progenitor cell differentiation 0.4407942238267082 0.2887736106340535 0.7727546278313189 1.0 0.958497842166975 2 Q92785 1 +Negative regulation of catabolic process 0.2632471112333757 0.2884865612660579 0.7729743160153904 1.0 0.958497842166975 89 P31749,Q9H2U1,P09601,Q9NWH9,Q9H074,Q9NZM5,P46379,P11940,P60520,Q16850,Q96HY6,P40763,Q04323 13 +Regulation of receptor localization to synapse 0.5191092455125379 0.2884780835903188 0.7729808045320519 1.0 0.958497842166975 4 Q9Y639 1 +Regulation of heart growth 0.3902500799722354 0.2880255967367949 0.7733271451679542 1.0 0.958497842166975 8 P80723,Q9UGN5 2 +Negative regulation of immune effector process 0.3803901983343044 0.2877968178163603 0.7735022733786123 1.0 0.958497842166975 9 P39019,P09601,Q08722 3 +Alpha beta t cell differentiation 0.3596444310995275 0.2876702754984577 0.7735991453409732 1.0 0.958497842166975 11 P40763,Q13951 2 +Erad pathway 0.2930412948642721 0.2869349253903058 0.7741621477786869 1.0 0.9586866416741796 35 Q8TCJ2,O76024,Q9BUN8,Q96A33,P46379,Q04323,Q9UNE7,Q9NYU2 8 +Positive regulation of amyloid beta formation 0.5341397179270992 0.2867312340548365 0.7743181199846609 1.0 0.9586866416741796 3 P42574 1 +Dna damage induced protein phosphorylation 0.4393501805054101 0.2845578200255479 0.7759829304549593 1.0 0.9588219726318808 2 O96017 1 +Establishment of epithelial cell polarity 0.4138027145548913 0.2831590442402882 0.7770549220076124 1.0 0.9588219726318808 6 P26038 1 +Establishment of epithelial cell apical basal polarity 0.4138027145548913 0.2831590442402882 0.7770549220076124 1.0 0.9588219726318808 6 P26038 1 +Positive regulation of axonogenesis 0.3245481880377203 0.2829597851300656 0.7772076644880461 1.0 0.9588219726318808 14 P07196 1 +Negative regulation of epithelial cell apoptotic process 0.4136914158958029 0.2828496990334633 0.777292054905373 1.0 0.9588219726318808 6 P09601 1 +Negative regulation of t cell proliferation 0.4221785783699436 0.2815205962498752 0.7783111330782864 1.0 0.9588219726318808 5 P42574 1 +Negative regulation of leukocyte proliferation 0.4221785783699436 0.2815205962498752 0.7783111330782864 1.0 0.9588219726318808 5 P42574 1 +Plasma membrane repair 0.4127047620334511 0.2801144494814442 0.7793896992130773 1.0 0.9592722340801892 6 Q8WUX9 1 +Regulation of protein phosphorylation 0.2557998465273415 0.2798283795891719 0.7796091773903215 1.0 0.9593553588077354 150 O75832,Q7KZI7,P36507,Q9UER7,P14635,Q9Y376,Q9Y639,P04792,Q13217,Q96HY6,O95429,Q13432,O43318,P31749,P31751,Q99640,Q9NZM5,Q13043,P49593,Q9NWS0,O14745,P42574,Q9Y3B8 23 +Osteoblast differentiation 0.2821492765471587 0.2786420650199688 0.780519527460833 1.0 0.959540556150253 38 P62841,Q13951,P31749 3 +T cell differentiation involved in immune response 0.5147709467764305 0.2781640850258399 0.7808864032643741 1.0 0.959617896109626 4 P40763,P42345 2 +Regulation of mitochondrial fusion 0.5139213044384019 0.2761668741355071 0.7824198988022681 1.0 0.9607229673201024 4 P02786 1 +Response to mineralocorticoid 0.3987048090188959 0.2757153041737449 0.7827667400625402 1.0 0.9607229673201024 7 P07196 1 +Negative regulation of ubiquitin protein ligase activity 0.3859866769187068 0.2752252575007917 0.7831431833247078 1.0 0.9607229673201024 8 P62841 1 +Embryonic morphogenesis 0.2792351716841554 0.2748855365867129 0.7834041793939357 1.0 0.9607229673201024 61 O95747,Q96A65,O75190,P42574,Q13043 5 +Negative regulation of actin filament bundle assembly 0.3856587780342206 0.2742520686434742 0.7838909164318668 1.0 0.9607229673201024 8 P16949,Q9NWH9,Q9Y624 3 +Cellular component disassembly 0.2661141795508649 0.273925475548421 0.7841418934450906 1.0 0.9607229673201024 132 Q7KZI7,P58546,P35609,Q9BWH2,O75844,Q6IBS0,Q12792,Q8WWK9,Q9UBB9,Q99661,Q96E11,Q9ULC4,Q96HY6,P17096,Q14197,Q99986,Q9BPX3,P60520,P53365,O95721,Q9UII2,O95140,Q9Y4P1,Q8WUX9,O43633,Q9Y3C8,O00139,P16949 28 +Negative regulation of small molecule metabolic process 0.3208677131498653 0.2733735817315429 0.7845660583347744 1.0 0.9607229673201024 15 Q13043,P31749 2 +Positive regulation of brown fat cell differentiation 0.5281183320625498 0.2726889685440894 0.7850923152784783 1.0 0.9607229673201024 3 Q16539 1 +Response to growth factor 0.2610252281274648 0.2724886712794495 0.7852463008489365 1.0 0.9607229673201024 88 Q9H4M9,Q9UQB8,Q6IBS0,O43318,P31749,Q9Y639,O43237,P04792,P42574,O14737,O95429,Q9UNE7 12 +Male gamete generation 0.2744644848184833 0.2717558224945768 0.785809775728056 1.0 0.9607229673201024 68 Q14141,A0AVF1,Q8IZT6,Q15067,Q9H2U1,Q96PU8,P68402,Q15102,Q9Y2W6,Q9H0H5,Q9Y508,P46379,P46100,O95470,O94901,Q9H6S0,P54619 17 +Positive regulation of lyase activity 0.4346570397111843 0.2710915089833056 0.7863206519944406 1.0 0.9607229673201024 2 Q9H1K1 1 +Regulation of mitochondrial electron transport nadh to ubiquinone 0.4346570397111843 0.2710915089833056 0.7863206519944406 1.0 0.9607229673201024 2 Q9H1K1 1 +Negative regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway 0.4346570397111842 0.271091508983305 0.786320651994441 1.0 0.9607229673201024 2 Q15233 1 +Dna damage response signal transduction by p53 class mediator 0.318785714209779 0.2707554686732442 0.7865791117501151 1.0 0.9607229673201024 16 O75844,P46100 2 +Cilium movement 0.3961820240729896 0.268558380950111 0.7882695431346827 1.0 0.961300513252297 7 Q96RL7,O14745 2 +Negative regulation of organelle organization 0.2633084230887851 0.267672168189746 0.7889516748528815 1.0 0.961300513252297 93 P04350,O75832,P60983,Q07157,P58546,P50570,P14635,Q6IBS0,O60264,Q12792,Q8WWK9,P31749,P50748,P02786,Q9NWH9,Q92974,Q9BPX3,Q00839,Q96KQ7,Q9NVN8,Q96PK6,Q9H3K2,Q7Z5K2,P46100,Q9Y624,P16949,P29372 27 +Neuron death 0.2781445268328295 0.2666175472550611 0.7897636437980347 1.0 0.961300513252297 61 Q15392,P20936,O75915,P31749,P07196,P31751,P09601,P04179,O76024,Q9UGN5,P42574,P51608,Q9UER7 13 +Renal water homeostasis 0.525155432153552 0.2659182239419509 0.7903021895780329 1.0 0.961300513252297 3 O76024 1 +Negative regulation of lipid localization 0.5090094014924738 0.2647685900670776 0.7911877350745196 1.0 0.9614523922352576 4 P31749 1 +Pyridine nucleotide metabolic process 0.5084788345188804 0.2635525855938868 0.7921246981957253 1.0 0.9614523922352576 4 P43490,Q9BQG2 2 +Regulation of transferase activity 0.2566224534958313 0.2606791526218669 0.7943399441441359 1.0 0.963166745557058 147 O75832,Q7KZI7,Q969S3,P36507,Q9UER7,P14635,P62841,Q9Y376,P04792,Q13432,O43318,P31749,Q16763,Q9NWH9,Q99640,P61088,Q13043,P49593,Q9BRX5,Q9NWS0,O14745,P42574,Q9Y3B8,Q9UNE7,P54619 25 +Regulation of vesicle size 0.5070696874972103 0.2603374659963042 0.7946034749761535 1.0 0.963166745557058 4 P20339 1 +Anterograde axonal transport 0.3299908546737121 0.2601130636473295 0.7947765613416704 1.0 0.9631898672382548 13 P04792,P07196 2 +Second messenger mediated signaling 0.3072811721724514 0.2595711211239842 0.7951946149315599 1.0 0.9632330173289726 20 O75844 1 +Inositol metabolic process 0.5222994043067473 0.2594795693876754 0.7952652436035745 1.0 0.9632330173289726 3 P51608 1 +Early endosome to golgi transport 0.3929324467902726 0.2594736217801621 0.7952698320139269 1.0 0.9632330173289726 7 Q13596 1 +Establishment or maintenance of monopolar cell polarity 0.3602415234293321 0.2557063744126499 0.7981775727062035 1.0 0.9652657472315742 10 P26038 1 +Protein k48 linked ubiquitination 0.3913200723327261 0.2550226178148112 0.7987056301745703 1.0 0.9652657472315742 7 O95071,Q13618,Q15386,Q13616,P63208,Q96J02 6 +Eosinophil mediated immunity 0.4288808664259875 0.2550187267772162 0.7987086354425192 1.0 0.9652657472315742 2 P51809 1 +Eosinophil activation 0.4288808664259875 0.2550187267772162 0.7987086354425192 1.0 0.9652657472315742 2 P51809 1 +Response to steroid hormone 0.2757559502788183 0.2547755609085954 0.7988964520820938 1.0 0.9652657472315742 62 Q969T9,P61353,O15173,Q16822,P07196,P42574,Q96HY6,Q9UER7 8 +Regulation of protein modification by small protein conjugation or removal 0.2711699312780573 0.2543254448607562 0.7992441437564448 1.0 0.9652657472315742 71 O75832,P62841,P31749,Q16763,Q9BUN8,Q9NZM5,O15294,Q04323,P61088,Q9UER7,Q9UNE7,Q9NVN8 12 +Response to starvation 0.2847017839193005 0.2540307607854782 0.7994717937289981 1.0 0.9652657472315742 36 Q8TEY7,Q16822 2 +Auditory receptor cell development 0.5040778263873892 0.2535814389239279 0.799818937612244 1.0 0.9652657472315742 4 O14745 1 +Response to light stimulus 0.2808848343831002 0.2533397948395536 0.8000056470166024 1.0 0.9652657472315742 52 P31749,Q9Y639,P31751,P42574,P51608,Q13432 6 +Sprouting angiogenesis 0.3276910889576317 0.2518226062252873 0.8011781830494411 1.0 0.9661203502554944 13 Q5JRA6,P09601,P31749 3 +Cellular process involved in reproduction in multicellular organism 0.2805976163859362 0.2496409830003776 0.8028650019425723 1.0 0.9668891957955928 46 Q8IZT6,P31749,Q96PU8,P78310,Q9Y2W6 5 +Cardiac muscle cell contraction 0.3770322128125534 0.2492413553320088 0.8031740916274837 1.0 0.9668891957955928 8 P14923 1 +Positive regulation of phosphorus metabolic process 0.2669215356713125 0.2475591003768403 0.8044755589385164 1.0 0.9668891957955928 117 O75832,Q7KZI7,Q969S3,Q14738,Q969H8,P36507,Q9UER7,P14635,Q9Y376,Q9Y639,Q96M27,Q96HY6,O95429,Q13432,O43318,P31749,Q15750,P06733,P02786,Q04637,Q9NWH9,P31751,Q8IV63,Q92797,Q92974,Q13043,O75116,Q9NWS0,P51116,Q86XL3,P54619 31 +Regulation of protein containing complex disassembly 0.2862688149062574 0.2470024870960944 0.8049062992784719 1.0 0.9668891957955928 35 O75844,Q6IBS0,Q12792,Q8WWK9,Q9BPX3,P58546,P35609 7 +Lung epithelium development 0.4087459342247904 0.2467609370730033 0.8050932434345743 1.0 0.9668891957955928 5 P09960,Q02750,P60953,Q13247 4 +Rna splicing via endonucleolytic cleavage and ligation 0.5005254801948702 0.2456847920039074 0.8059262456541585 1.0 0.9668891957955928 4 Q92499,Q92989 2 +Protein complex oligomerization 0.2788109024980708 0.2454904442174587 0.80607670625696 1.0 0.9668891957955928 55 O95202,Q9H4M9,O43633,Q99797,Q96CX2,Q8NE86,Q04837,Q15070,O60701,Q9NXV2,P31350,Q96TA2,P04179,Q13043,Q9NPJ3,Q16630,Q9UJZ1 17 +Feeding behavior 0.4081594285381391 0.2452967050641442 0.8062267028118484 1.0 0.9668891957955928 5 P40763 1 +Embryo development ending in birth or egg hatching 0.2659018106248977 0.2451831062529145 0.8063146564980603 1.0 0.9668891957955928 107 O95747,Q01968,P31749,Q96ST3,O75190,Q9Y5P4,P42574,Q13043,P14635 9 +Polysaccharide metabolic process 0.3087851859792582 0.2450615283382087 0.8064087907054407 1.0 0.9668891957955928 18 Q16851,P31751,P31749 3 +Regulation of tolerance induction 0.5156922038834919 0.2449190517351537 0.8065191097223956 1.0 0.9668891957955928 3 P01889 1 +Tolerance induction 0.5156922038834919 0.2449190517351537 0.8065191097223956 1.0 0.9668891957955928 3 P01889 1 +T cell proliferation 0.3001114388040938 0.2448568371579678 0.8065672834078346 1.0 0.9668891957955928 25 P02786,Q92542,P32119,P26038,P42574,P62753,Q96EY1 7 +Regulation of cardiac muscle contraction 0.3753778809046147 0.2445777592569941 0.8067833866624501 1.0 0.9668891957955928 8 P14923 1 +Response to glycoside 0.4245487364620877 0.2433335423613881 0.807747022073138 1.0 0.9668891957955928 2 O96017 1 +Zymogen activation 0.3869789396407648 0.2432282803163298 0.8078285600393105 1.0 0.9668891957955928 7 Q15392 1 +Telencephalon development 0.2798098405025198 0.2429839848000883 0.8080178039988224 1.0 0.9668891957955928 37 Q96P11,P07196,Q8IZT6,P42574 4 +Mitotic recombination 0.3655446977922545 0.2426473034966522 0.808278633181396 1.0 0.9668891957955928 9 Q8IY18,P20585,Q96SB8,Q92878,P18887,P49959,P43246,P18074 8 +Regulation of ras protein signal transduction 0.2985208990865506 0.2413046476502204 0.8093190090059657 1.0 0.9668891957955928 26 O95140,P20936,P52565,Q9NWH9,Q9UQ13,Q68EM7,Q92974,Q9Y624,O15294,P16949,P50570 11 +Hair cell differentiation 0.3860862127861975 0.2408374498429235 0.809681102971606 1.0 0.9668891957955928 7 O14745,P18074 2 +Regulation of carbohydrate biosynthetic process 0.3076802849753583 0.2405715417834594 0.8098872088326483 1.0 0.9668891957955928 18 Q13043,P31751,P31749 3 +Peptidyl histidine modification 0.4234657039711118 0.2404623318500055 0.8099718614877143 1.0 0.9668891957955928 2 Q9BQC3 1 +Monosaccharide biosynthetic process 0.2982943955113397 0.2402306738342708 0.8101514355342849 1.0 0.9668891957955928 26 Q13043,Q16822,Q9UBX3 3 +Negative regulation of microtubule polymerization or depolymerization 0.3243803710664223 0.240094586462886 0.8102569308676344 1.0 0.9668891957955928 13 P04350,Q8WWK9,P16949,P29372 4 +Organelle fission 0.2626303346747566 0.2382688161442802 0.8116726060297292 1.0 0.9672940011954646 133 Q02241,Q53EZ4,P14635,Q53HL2,Q14004,Q99661,Q9NQW6,Q8NE86,Q9BZD4,Q9NTI5,Q8IZT6,P50748,Q16763,Q9Y2W6,Q9H0H5,Q99640,Q9BPX3,Q9UDX5,Q00839,O43663,Q8WUX9,P42695,O00139,P46379,P46100,O94901 26 +Golgi localization 0.4052967678152899 0.2382156495002678 0.8117138399066544 1.0 0.9672940011954646 5 O14745,P48444 2 +Regulation of cytoplasmic translation 0.3112374200830965 0.2362941752262067 0.8132044064795183 1.0 0.9677539480952188 15 Q9H2U1,Q9H074 2 +Cristae formation 0.3720273542554945 0.2352662365152698 0.8140020990534802 1.0 0.9683832445190772 8 O95202 1 +Spermatid differentiation 0.3037340961531752 0.2333839258173603 0.8154632939200273 1.0 0.9687366392871218 19 A0AVF1,Q96PU8,Q9H6S0,Q96KQ7,Q14997 5 +Regulation of striated muscle contraction 0.3613518171411564 0.2305616485010461 0.817655364931628 1.0 0.969862557381165 9 P14923 1 +Mitotic sister chromatid cohesion 0.3215742237312855 0.2303483551678527 0.8178210886842119 1.0 0.969862557381165 13 P46100 1 +Regulation of tor signaling 0.3090191221539674 0.2280807302106783 0.8195834803726729 1.0 0.9698952724160512 15 O75844,Q6IAA8,Q9NWS0 3 +L amino acid transport 0.3511440609948957 0.228003651515255 0.8196434017871574 1.0 0.9698952724160512 10 O60831,P08195,Q9Y619,O75915 4 +Amino acid transmembrane transport 0.3511440609948957 0.228003651515255 0.8196434017871574 1.0 0.9698952724160512 10 O60831,P08195,Q9Y619,O75915 4 +Voluntary musculoskeletal movement 0.5074033947273449 0.2273249722921515 0.8201710562801379 1.0 0.9698952724160512 3 P18887,P42345 2 +Sister chromatid segregation 0.2616513632770648 0.2271951355300889 0.8202720100881316 1.0 0.9698952724160512 80 Q02241,Q53EZ4,P14635,Q53HL2,O60264,O95239,Q99661,Q9BZD4,Q9NTI5,P50748,Q9H0H5,Q9BPX3,Q00839,O43663,Q8WUX9,P42695,Q7Z5K2,O43633,P46100 19 +Regulation of proton transport 0.3601556642621806 0.2271693807801897 0.8202920358959036 1.0 0.9698952724160512 9 Q8TAD4,O14745,Q9UHD1 3 +Inorganic anion transmembrane transport 0.3808110144906104 0.2269543530824955 0.820459236940152 1.0 0.9698952724160512 7 Q9UHG3 1 +Cellular response to leucine starvation 0.5068952080198925 0.2262709444028815 0.8209906953917969 1.0 0.9700103388293048 3 P42345 1 +Transcytosis 0.3798424953060453 0.2244513147723281 0.8224061456408911 1.0 0.9701545473087584 7 P20339 1 +Response to radiation 0.2646061024698682 0.2243525743918784 0.8224829702113219 1.0 0.9701545473087584 76 O75844,P31749,Q9Y639,P31751,Q9BVC6,P46100,P42574,P51608,Q13432 9 +Positive regulation of protein sumoylation 0.5059588299024994 0.2243363269725502 0.8224956116160571 1.0 0.9701545473087584 3 Q9UBT2,Q9UBE0 2 +Biological process involved in intraspecies interaction between organisms 0.4903571082816698 0.2238439311221352 0.8228787450851718 1.0 0.9702726613694126 4 Q96RL7 1 +Production of molecular mediator involved in inflammatory response 0.3396085823483915 0.2223273649642037 0.8240590509657493 1.0 0.9709104026493264 11 Q16539,P39019,P40763,O00161 4 +Regulation of nucleotide metabolic process 0.3071571760825405 0.2212841656488834 0.824871178378678 1.0 0.9713843908313738 15 P06733,O15294,P40763,P54619 4 +Positive regulation of podosome assembly 0.4887937767622656 0.2205876890076052 0.8254134876996257 1.0 0.9713843908313738 4 P26038 1 +Regulation of podosome assembly 0.4887937767622656 0.2205876890076052 0.8254134876996257 1.0 0.9713843908313738 4 P26038 1 +Positive regulation of cell cycle process 0.2679438798075502 0.2204911355809447 0.825488675300103 1.0 0.9713843908313738 68 P31749,Q96ST3,Q7Z7K6,Q9H0H5,P46100,Q96HY6,P51608,P14635 8 +Dna replication independent chromatin organization 0.3898423470015582 0.2204274479356593 0.8255382707002141 1.0 0.9713843908313738 6 P46100 1 +Regulation of response to interferon gamma 0.4151624548736388 0.2191242481221628 0.8265532624696339 1.0 0.9720352578195696 2 P08238 1 +Regulation of mitotic spindle assembly 0.3568815029108985 0.2180116380364374 0.8274200436761512 1.0 0.9726922650849412 9 Q8WUX9,Q00839 2 +Coenzyme a biosynthetic process 0.3885026435259728 0.2171573520526407 0.8280857197159812 1.0 0.9732936028083964 6 Q13057,Q8WVC6 2 +Erk1 and erk2 cascade 0.2831143784322593 0.2161183287318285 0.8288955130434419 1.0 0.9738828190093584 34 P57105,Q02952,Q9Y639,Q8IV63,O14745,P36507,P04899 7 +Mitotic sister chromatid segregation 0.2665330076920885 0.2143142268727083 0.8303020243361785 1.0 0.974844120708116 70 Q8WUX9,Q02241,Q53HL2,P42695,O60264,O43633,O95239,P50748,Q53EZ4,O43663,Q99661,Q9BZD4,Q9H0H5,Q9BPX3,P46100,Q00839,P14635,Q9NTI5 18 +Regulation of t cell activation 0.2748665440534308 0.2138522947171278 0.830662242856611 1.0 0.974844120708116 37 Q13951,P31749,Q96EY1 3 +Positive regulation of interleukin 2 production 0.3754462876770266 0.2132711169109371 0.8311155006652593 1.0 0.974844120708116 7 O43318 1 +Rna methylation 0.2938153390258405 0.2126270870046018 0.831617842148676 1.0 0.974844120708116 23 Q9UJA5,Q7Z4G4,Q96P11,Q96T37 4 +Dopamine receptor signaling pathway 0.3865738706409406 0.2124950703165352 0.8317208232902471 1.0 0.974844120708116 6 O14745 1 +Mitotic spindle organization 0.273470863259999 0.2116507093897821 0.8323795450339972 1.0 0.9749444291413074 56 Q8WUX9,Q02241,Q9HBM1,O00139,Q9BZD4,Q9H0H5,Q00839,P51608,P16949,P14635,O43663 11 +Positive regulation of dna dependent dna replication 0.3859100072244534 0.2109028869343282 0.8329630513483346 1.0 0.9749444291413074 6 Q04837 1 +Negative regulation of intracellular protein transport 0.3627327939827772 0.2103915837195722 0.8333620608768328 1.0 0.9749579493007824 8 O95429,Q9GZP9 2 +Erythrocyte development 0.3854785245388414 0.2098714866386539 0.8337679769791739 1.0 0.9752521316499636 6 Q9NRK6,P18074 2 +Energy reserve metabolic process 0.3011601189544235 0.2084846478908714 0.8348505684897769 1.0 0.975698967728192 17 Q16851,P31751,P31749 3 +Heart growth 0.3349216671035542 0.2081752910893977 0.8350921008023267 1.0 0.9757164182949464 11 P80723 1 +Endocytosis 0.2556511223410846 0.2049124883838608 0.837640497932568 1.0 0.9776687873386876 91 Q8TEY7,Q01518,Q8NBU5,P84095,P62820,P30533,Q08209,Q8WTV0,P57105,Q13596,P20645,Q5JRA6,Q13432,Q9H4M9,Q8NC96,O94973,P20339,O15260,Q9NVZ3,Q96T51,Q9P2R3 21 +Regulation of histamine secretion by mast cell 0.409025270758117 0.2041297080338756 0.838252139426156 1.0 0.9776687873386876 2 P51809 1 +Negative regulation of epidermal growth factor activated receptor activity 0.4090252707581157 0.2041297080338725 0.8382521394261584 1.0 0.9776687873386876 2 Q99816 1 +Regulation of epidermal growth factor activated receptor activity 0.4090252707581157 0.2041297080338725 0.8382521394261584 1.0 0.9776687873386876 2 Q99816 1 +Regulation of endoplasmic reticulum tubular network organization 0.4953754332522156 0.2031539388497548 0.839014713523013 1.0 0.9776687873386876 3 P57088 1 +Regulation of sodium proton antiporter activity 0.4953286467252217 0.2030631064426075 0.8390857077270111 1.0 0.9776687873386876 3 O14745 1 +Regulation of organelle organization 0.2566910178560149 0.2026192623686844 0.8394326330961661 1.0 0.977892554496161 279 Q9UQB8,O75832,Q7KZI7,Q9H2U1,P36507,P58546,P35609,Q92783,P14635,Q6IBS0,Q14004,Q96ST3,Q8WWK9,Q8NE86,P26038,O95429,P20936,P31749,P50748,Q7Z7K6,Q9NWH9,P31751,Q04837,P53365,Q9UII2,P20339,P49593,Q9Y3P9,Q9NVN8,Q8WUX9,Q7Z5K2,P46100,O14737,P51608 34 +Cellular protein catabolic process 0.2567329359556988 0.2016238323697542 0.8402108123113308 1.0 0.9779618369270892 205 Q8TEY7,Q92783,O14773,O75844,P49721,P26038,Q13217,Q96TA2,Q96HY6,P55036,O00487,P31749,Q16763,Q9BUN8,Q9NZM5,Q96A33,P60520,Q9UII2,Q9NYU2,Q8WUX9,Q96RL7,Q9Y508,Q9NXV2,P46379,Q9UHG3,Q9UNE7 26 +Positive regulation of defense response 0.2753839542802245 0.2006504711453884 0.840971890269165 1.0 0.9779618369270892 36 Q96ST3,P33527 2 +Protein export from nucleus 0.290952093248374 0.2003517298592158 0.8412055080193228 1.0 0.9779618369270892 23 Q9Y3B8 1 +Torc2 signaling 0.4938856103522464 0.2002737949229623 0.8412664559786165 1.0 0.9779618369270892 3 Q9NWS0 1 +Chromosome condensation 0.2908283375154883 0.1998274172451413 0.8416155579013642 1.0 0.9779618369270892 23 P42695,Q7Z5K2,O60264,P10412,P16403,P16402,Q92522,P07305,Q9BPX3,O95347,Q9NTJ3 11 +Positive regulation of g1 s transition of mitotic cell cycle 0.3018747977616277 0.1994182837388174 0.8419355593502489 1.0 0.9779618369270892 14 P31350,Q04637,Q7L2J0,P31749 4 +Dna templated transcription initiation 0.2876492323655119 0.1993738541185525 0.8419703112980135 1.0 0.9779618369270892 28 O15160,O60264,O75448,P62805,Q9H2U1,Q14241,Q9NWS0,Q15369,P62333 9 +Sister chromatid cohesion 0.2902894119705195 0.1983981095996287 0.8427335963697742 1.0 0.978453538854443 24 Q7Z5K2,P46100 2 +Acetyl coa biosynthetic process from pyruvate 0.3879026780036223 0.1975912373923364 0.8433648911874578 1.0 0.978453538854443 5 P11177,P10515,Q15120 3 +Regulation of vasculature development 0.2846354054538504 0.1973663530797179 0.8435408580703385 1.0 0.978453538854443 31 P57105,O75116,P14923,Q9NZ08,P09601,Q86UE4,P04792,P40763,P51608 9 +Post golgi vesicle mediated transport 0.2687698608598164 0.1967556895453728 0.8440187278350311 1.0 0.978616094312717 38 Q96KP1,O75608,O15126,Q96RL7,Q8TAG9,Q9P2R3,O00161,Q8IWJ2,Q96A65 9 +Vascular process in circulatory system 0.2877660401880016 0.1963767366190915 0.8443153032378687 1.0 0.978616094312717 27 Q01469,P33527 2 +Regulation of microtubule depolymerization 0.3569665071835697 0.1956827815874534 0.8448584621632278 1.0 0.978616094312717 8 Q8WWK9,P29372 2 +Regulation of rac protein signal transduction 0.4747722374398105 0.1926182640437196 0.8472579401466835 1.0 0.9790605113627672 4 Q68EM7,O15294 2 +Regulation of atp metabolic process 0.2889229678509235 0.1920816099808492 0.8476782797947606 1.0 0.979317981721617 22 Q9UII2,O15294,P40763 3 +Cell fate commitment 0.2972047751037203 0.1899537548796719 0.8493453689181667 1.0 0.9799438827590466 16 Q14318,P40763,Q92974,P42574,Q96KQ7 5 +Negative regulation of chromosome organization 0.2816748895989455 0.1897309021915006 0.8495200041750577 1.0 0.9799438827590466 32 Q7Z5K2,P46100,P14635,Q9NVN8 4 +Negative regulation of dna recombination 0.2986263018229333 0.1885136975664473 0.8504739789058309 1.0 0.9802201072795588 14 P07305,P16403 2 +Regulation of cell cycle g2 m phase transition 0.2797729100158101 0.1884872827770524 0.8504946837250891 1.0 0.9802201072795588 33 Q96ST3,Q9NZM5,P14635 3 +Positive regulation of nucleocytoplasmic transport 0.2878921350920631 0.1882330530367618 0.850693962996707 1.0 0.9802201072795588 24 P14923,Q9Y3B8,Q9C0E2 3 +Positive regulation of nitric oxide synthase biosynthetic process 0.4871143004058343 0.1875029925415698 0.8512662775907478 1.0 0.9804624729492852 3 P43490 1 +Nitric oxide synthase biosynthetic process 0.4871143004058343 0.1875029925415698 0.8512662775907478 1.0 0.9804624729492852 3 P43490 1 +Purine containing compound transmembrane transport 0.3535237365763349 0.1871704905773524 0.8515269610530121 1.0 0.9805774574851748 8 O15439,Q8TB61 2 +Amino acid transport 0.2973462250047577 0.1869794889941814 0.851676714736886 1.0 0.9805774574851748 15 O75915,Q9Y619,O14745,Q6P4A7,P08195 5 +Spermidine metabolic process 0.4014440433212941 0.186532694912573 0.8520270419251144 1.0 0.9806231758503776 2 P49366 1 +Cell cycle g2 m phase transition 0.2689145731870425 0.1846958636550141 0.8534675906870599 1.0 0.9815654585788882 42 Q96ST3,Q9NZM5,O43768,P14635 4 +Positive regulation of stress fiber assembly 0.3072531492328436 0.1834906131087368 0.8544130833945474 1.0 0.9816943682809424 13 O75116,O95429,P49593 3 +Positive regulation of organelle organization 0.2580356607178817 0.1834317150300631 0.8544592930199224 1.0 0.9816943682809424 132 Q9UQB8,Q96ST3,P51608,Q9NWH9,Q8NE86,P31751,Q04837,P35609,P26038,P46100,O14737,Q9UII2,P49593 13 +Chondrocyte differentiation involved in endochondral bone morphogenesis 0.3999999999999931 0.1832977813212463 0.8545643751565986 1.0 0.9816943682809424 2 P50454 1 +Nuclear membrane organization 0.2939786225221685 0.1825983956124351 0.8551131432945414 1.0 0.9816998189967469 17 Q8WUX9,Q5JTV8,Q99986,O43633 4 +In utero embryonic development 0.2590773277201562 0.1798826460667183 0.8572446993980221 1.0 0.9830093568537452 76 Q01968,P31749,Q96ST3,O75190,Q9Y5P4,P14635 6 +Sensory organ development 0.2696859665245915 0.1790275768754009 0.8579160482768797 1.0 0.983170303577877 50 O95747,Q99797,P40763,Q9Y4P1,O95140 5 +Cdc42 protein signal transduction 0.3971119133573951 0.1769406836571021 0.8595549818301926 1.0 0.9844450049684184 2 P60953 1 +Cell maturation 0.2890199748685388 0.1759966163407092 0.860296600725103 1.0 0.9849343131420308 19 Q13951,Q9Y2W6 2 +Positive regulation of protein catabolic process 0.2664499798896441 0.1746393052239301 0.8613630620577002 1.0 0.9852330556560368 59 O75832,P31749,P26038,Q9NZM5,P46379,Q96HY6,Q9UII2,Q9UNE7 8 +Nucleoside triphosphate biosynthetic process 0.2748325563628142 0.1732653072678044 0.8624428920075684 1.0 0.9852330556560368 34 O75947,P00568,P12268,P06733,Q9NRF8,P30085,Q9BZX2,P00846,P56385,P06576,Q9UJZ1 11 +Circadian rhythm 0.2662775799235705 0.1723693232561165 0.8631471876899717 1.0 0.9852330556560368 41 Q03164,Q96ST3,Q9BQG2,Q00839,P43490,O15294 6 +Positive regulation of protein localization to membrane 0.2822447128376513 0.1723032486959145 0.8631991304609219 1.0 0.9852330556560368 27 O14737,P31749 2 +Regulation of intracellular protein transport 0.2669935243315786 0.1718564210507034 0.8635504077270324 1.0 0.9852330556560368 57 Q4V328,Q9UII2,Q9C0E2,Q9Y282,P14923,P31751,O14737,Q8IWJ2,Q9Y3B8 9 +Regulation of receptor signaling pathway via stat 0.357874005837851 0.1716256469964263 0.8637318432355618 1.0 0.9852330556560368 7 Q13043,Q6IA86 2 +Positive regulation of defense response to virus by host 0.3683154495233448 0.1710886577665316 0.8641540541713963 1.0 0.9854196673357768 6 Q96ST3 1 +Endoplasmic reticulum unfolded protein response 0.2836487707181078 0.1703162811304693 0.864761407831991 1.0 0.985583876322358 23 P57088,O76024,Q9BUN8,Q96HY6,Q9UNE7 5 +Programmed cell death involved in cell development 0.4772901790685795 0.1699130338301816 0.8650785306586171 1.0 0.985583876322358 3 P42575 1 +Ectopic germ cell programmed cell death 0.4772901790685795 0.1699130338301816 0.8650785306586171 1.0 0.985583876322358 3 P42575 1 +Rac protein signal transduction 0.3296233330206854 0.168690057342053 0.8660404397926176 1.0 0.9865017746438008 10 P84095,Q68EM7,O15294 3 +Regulation of glucagon secretion 0.392779783393496 0.1676874877413988 0.8668291401384687 1.0 0.9865497337842762 2 Q96RG2 1 +Cranial skeletal system development 0.3665943600867564 0.1674448596057144 0.8670200305304006 1.0 0.9865497337842762 6 P11586,Q6UB35,P35222,Q53EZ4,P46109 5 +Positive regulation of signal transduction by p53 class mediator 0.3289274967613106 0.1669239614350718 0.8674298791600834 1.0 0.9868095810296084 10 P62841,P62829,P62081 3 +Actin mediated cell contraction 0.3288423812514253 0.1667085974796435 0.8675993403991855 1.0 0.9868095810296084 10 P14923 1 +Cellular response to reactive oxygen species 0.2808855014261637 0.1665587381716639 0.8677172622547331 1.0 0.9868095810296084 27 Q9NWH9,P31749 2 +Regulation of spindle assembly 0.3200284771806204 0.1662331907437027 0.8679734403772534 1.0 0.986923159110747 11 Q8WUX9,O43633,Q14204,Q8WUM4,Q00839 5 +Regulation of peptidyl threonine phosphorylation 0.365523164399369 0.1651998690673479 0.8687866683184606 1.0 0.9871893781124408 6 Q9Y376 1 +Regulation of proteasomal ubiquitin dependent protein catabolic process 0.2665987101757843 0.1649200189824382 0.8690069352861947 1.0 0.9871893781124408 45 O75832,P31749,Q9NZM5,P46379,Q04323,Q96HY6,Q9UNE7 7 +Epithelial cell proliferation involved in lung morphogenesis 0.4743241664868202 0.1648221593639729 0.8690839619308142 1.0 0.9871893781124408 3 Q02750 1 +Negative regulation of protein containing complex assembly 0.2728548192463481 0.1635125333255898 0.8701149057877497 1.0 0.9874021414708576 34 Q6IBS0,Q12792,Q9UBB9,Q9NZM5,Q9BPX3,P58546,P16949 7 +Purine nucleotide transport 0.3261694783234861 0.160019645285989 0.8728655989282466 1.0 0.9887071056649108 10 O15439,Q8TB61,Q99808 3 +Establishment of protein localization to chromosome 0.2890188038912743 0.1599166689986554 0.8729467175446022 1.0 0.9887071056649108 15 Q9P0M6 1 +Nadph regeneration 0.3418625837016224 0.1598650914136619 0.8729873478115104 1.0 0.9887071056649108 8 P37837,P29401 2 +Transcription elongation from rna polymerase i promoter 0.4707106553943678 0.1587580880871362 0.8738594707896763 1.0 0.9891625490437462 3 P18074 1 +Dendritic transport 0.368991687748457 0.1582792374207196 0.8742367680412517 1.0 0.9894122519111784 5 Q00839,P23246,Q14254,P33176 4 +Animal organ regeneration 0.2980012081472989 0.1558858058601316 0.8761230338098633 1.0 0.9903638244781846 13 P09601 1 +Histone modification 0.2577634607509679 0.1552357858773296 0.8766354371838938 1.0 0.9903638244781846 117 Q03164,O75844,Q969T9,O75448,P16403,Q96ST3,Q86YP4,Q9UGN5,O43318,Q9UHR5,Q99986,P61088,Q13043,P49593,P10412,Q9BV86,Q9NWS0,P46100,P51608 19 +Monosaccharide metabolic process 0.2607686071542123 0.1545128520357082 0.8772053784487301 1.0 0.9903638244781846 63 O75844,P31749,Q16822,P31751,Q01469 5 +Negative regulation of nucleocytoplasmic transport 0.3668232743043003 0.1541035408423452 0.877528096443771 1.0 0.9903638244781846 5 Q9UHD1,Q99497,P12270,P46060 4 +Podosome assembly 0.3667727730062169 0.1540071127038013 0.8776041273697093 1.0 0.9903638244781846 5 P26038 1 +Cerebellar purkinje cell layer development 0.3585767750007971 0.1510700828171827 0.8799204320659113 1.0 0.9903638244781846 6 O14949,P48444 2 +Protein dephosphorylation 0.2649692104403319 0.1510105696361366 0.8799673781537161 1.0 0.9903638244781846 51 O75116,Q9H0C8,Q15750,O43768,Q9NQG5,Q08209,Q8IV63,Q92797,P04899,Q86XL3,P49593 11 +Telomere maintenance via recombination 0.3650162631008282 0.1506765060702445 0.8802309070560561 1.0 0.9903638244781846 5 Q96SB8,P18887,Q92878,Q8IY18 4 +Epithelial cell development 0.275456848622333 0.1506639849690347 0.880240784691976 1.0 0.9903638244781846 30 P26038,Q9Y3B8,Q9NWH9,P31749 4 +Developmental pigmentation 0.3479204339963714 0.1502568979411545 0.880561937310959 1.0 0.9903638244781846 7 Q86YV9,Q9BXS5,O14617,Q07812,Q96AX1,P04179 6 +Cd4 positive alpha beta t cell activation 0.3477569684850226 0.1499196109414207 0.880828039285922 1.0 0.9903638244781846 7 P40763,Q9UJZ1,P42345,Q13951 4 +Regulation of rna polymerase ii transcription preinitiation complex assembly 0.4506706979692635 0.1498523634254746 0.8808810957031177 1.0 0.9903638244781846 4 P09429,P62333 2 +Rna polymerase ii preinitiation complex assembly 0.4506706979692635 0.1498523634254746 0.8808810957031177 1.0 0.9903638244781846 4 P09429,P62333 2 +Protein localization to adherens junction 0.4505057803468324 0.149583178787658 0.8810934802366333 1.0 0.9904262478572372 4 Q13112,Q14160,Q07157 3 +Rhythmic process 0.2642371054015791 0.1488963334867254 0.8816354344181954 1.0 0.9905064293445704 54 Q03164,Q96ST3,O95470,P42574,P43490 5 +Extrinsic apoptotic signaling pathway 0.2599444729137415 0.1479689728349299 0.8823672547449595 1.0 0.9910190745160982 38 Q13043,P09601,Q9UGN5,P31749 4 +Vacuolar localization 0.2851219724822657 0.1479203294556756 0.8824056441130035 1.0 0.9910190745160982 15 P09601,O00161 2 +Negative regulation of intrinsic apoptotic signaling pathway 0.2747052751873025 0.1474385495152431 0.8827858798740522 1.0 0.991269792908548 30 Q12931,Q96QE3,P31749,O75489,P06733,P04792,O76024,Q92974,P04179 9 +Regulation of small gtpase mediated signal transduction 0.2667380935593672 0.1437027930641089 0.8857351655477343 1.0 0.9929073406322296 35 O95140,P20936,P35241,P52565,Q9NWH9,Q9UQ13,Q68EM7,Q9H0H5,Q92974,Q9Y624,Q4VCS5,O15294,P16949,P50570 14 +Transcription by rna polymerase iii 0.2819250696922272 0.1425373925524674 0.8866555458946577 1.0 0.9936711247388832 17 Q9H2U1,O15160,O60264,P35659 4 +Regulation of macroautophagy 0.2625698935096342 0.139372760329409 0.8891555963634077 1.0 0.9955893661001164 47 P21281,O43318,P31749,P09601,Q96A65 5 +Regulation of neurotransmitter receptor activity 0.3779783393501737 0.138633915821668 0.8897394411381649 1.0 0.9958898832381444 2 P07384 1 +Regulation of nmda receptor activity 0.3779783393501737 0.138633915821668 0.8897394411381649 1.0 0.9958898832381444 2 P07384 1 +Ketone body metabolic process 0.4569470934319683 0.137051959747453 0.8909897246190253 1.0 0.9961796101842364 3 P35610 1 +Glutamine family amino acid biosynthetic process 0.3409734391008621 0.136314373217616 0.8915727617600393 1.0 0.9961796101842364 7 P32322 1 +Regulation of viral genome replication 0.2747715473060561 0.136282412115318 0.8915980272550581 1.0 0.9961796101842364 24 O95793 1 +Regulation of retinoic acid receptor signaling pathway 0.4418547363489918 0.1359112015117122 0.8918914801222417 1.0 0.9961796101842364 4 A5YKK6,P56545 2 +Outflow tract morphogenesis 0.4418352601156187 0.1358814143294043 0.8919150284055255 1.0 0.9961796101842364 4 Q12948,P60953,P35222 3 +R loop disassembly 0.4557602022390774 0.1352832624970877 0.8923879180111773 1.0 0.9961796101842364 3 Q9BUQ8,Q9NR30 2 +Positive regulation of lymphocyte apoptotic process 0.3758122743682252 0.1347137478754213 0.8928382030460225 1.0 0.9961796101842364 2 Q07812 1 +Regulation of transcription from rna polymerase ii promoter in response to hypoxia 0.3758122743682252 0.1347137478754213 0.8928382030460225 1.0 0.9961796101842364 2 Q8IXJ6 1 +Positive regulation of transcription from rna polymerase ii promoter in response to stress 0.3758122743682245 0.1347137478754199 0.8928382030460236 1.0 0.9961796101842364 2 Q92616 1 +Positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus 0.3758122743682243 0.1347137478754196 0.8928382030460238 1.0 0.9961796101842364 2 Q9NXV6 1 +Regulation of behavior 0.3497974812619757 0.1342807647134506 0.893180563014881 1.0 0.9963855255964592 6 P40763 1 +Copii coated vesicle cargo loading 0.338792758233465 0.1321035629247901 0.8949023778068881 1.0 0.996796362571248 7 Q5JRA6,P62820,O95486 3 +Morphogenesis of a polarized epithelium 0.2979966784218043 0.1318091817282138 0.8951352239525003 1.0 0.996796362571248 12 P26038 1 +Response to cocaine 0.3541068888649795 0.1310080978946005 0.8957689014262737 1.0 0.996796362571248 5 Q96KQ7,P50570 2 +Regulation of epithelial cell apoptotic process 0.3208975928372578 0.1302680767978868 0.896354335843303 1.0 0.996796362571248 9 P09601 1 +Positive regulation of g protein coupled receptor signaling pathway 0.3732851985559507 0.1302465596306455 0.8963713590285975 1.0 0.996796362571248 2 P35232 1 +Positive regulation of production of mirnas involved in gene silencing by mirna 0.4375425439942106 0.1294247316134227 0.8970215792584268 1.0 0.9969713521277428 4 P36507 1 +Viral rna genome replication 0.2955328739415908 0.125736681669298 0.8999403645083521 1.0 0.9987992139004128 12 Q15366,P20339 2 +Negative regulation of proteolysis involved in cellular protein catabolic process 0.2712917983385122 0.1256596927937305 0.9000013093712342 1.0 0.9987992139004128 26 Q9NZM5,P46379,Q04323,P60520,Q96HY6 5 +Megakaryocyte differentiation 0.3351253200754325 0.1252009092021718 0.9003644974703044 1.0 0.9987992139004128 7 Q96T37 1 +Negative regulation of cyclin dependent protein serine threonine kinase activity 0.3501891031558327 0.1243732007082587 0.9010197913108884 1.0 0.9987992139004128 5 P42574 1 +Endoplasmic reticulum tubular network organization 0.3244923340318805 0.1236550556875738 0.9015883988177696 1.0 0.9989093535256924 8 O95197,P57088 2 +Protein targeting to lysosome 0.3010842433924615 0.1198053252794467 0.904637363368257 1.0 1.0 11 P20645 1 +Cellular defense response 0.4442430285756944 0.1189657305660905 0.9053025059707912 1.0 1.0 3 Q08380 1 +Recombinational repair 0.2589230194712376 0.1180940388091238 0.9059931467423266 1.0 1.0 54 O94761,P35244 2 +Rna decapping 0.340639404733659 0.1180455320205233 0.9060315807302172 1.0 1.0 6 Q96F86 1 +Methylguanosine cap decapping 0.340639404733659 0.1180455320205233 0.9060315807302172 1.0 1.0 6 Q96F86 1 +Negative regulation of mrna 3 end processing 0.345861944344052 0.117307938545277 0.9066160344182324 1.0 1.0 5 Q6PJT7,Q6PD62,O75150,P18615 4 +Regulation of cellular protein catabolic process 0.2486163422448363 0.1164690276213765 0.907280831391814 1.0 1.0 79 O00487,P31749,P26038,Q9NZM5,P46379,P60520,Q96HY6,Q9UII2,Q9UNE7 9 +Homocysteine metabolic process 0.4421258205820648 0.1161319049417681 0.907548003390814 1.0 1.0 3 Q13867 1 +Spliceosomal snrnp assembly 0.268812036398217 0.1152008293254206 0.9082859413478576 1.0 1.0 23 Q9Y333,P62314,Q9Y312,P54105 4 +Regulation of t cell proliferation 0.2721083991538602 0.1151497755421908 0.90832640708511 1.0 1.0 18 Q96EY1 1 +Monocarboxylic acid transport 0.3132290021133717 0.1147353483663777 0.9086548949878568 1.0 1.0 9 O15439 1 +Viral release from host cell 0.2821699468838742 0.1137194041645515 0.909460230008323 1.0 1.0 13 Q8WUX9 1 +Regulation of protein targeting 0.2691557583654531 0.1135883543244621 0.909564119499988 1.0 1.0 20 O14737,Q9UII2,P31751 3 +Scarna localization to cajal body 0.3429707264184981 0.1127406980088789 0.9102361345782908 1.0 1.0 5 O60832,P17987,Q9BUR4,P50991 4 +Blastocyst formation 0.2898675864026486 0.112326283538275 0.9105647024267352 1.0 1.0 12 Q9NVX2,O95140 2 +Positive regulation of tor signaling 0.3272747895774732 0.1111799328277853 0.911473664250505 1.0 1.0 7 Q9NWS0 1 +Succinate metabolic process 0.4241329479768865 0.1106419508285017 0.9119002797414512 1.0 1.0 4 P51649,Q9P2R7,P31040 3 +Sarcomere organization 0.3264767910679816 0.1098122551154122 0.9125582716503498 1.0 1.0 7 P35609,Q15149 2 +Regulation of cellular component biogenesis 0.247113123043566 0.1097609341947621 0.9125989737865698 1.0 1.0 193 Q9UQB8,P58546,Q71SY5,Q92783,Q6IBS0,O75027,Q96ST3,Q9UBB9,Q9NQW6,P26038,P20936,Q9NWH9,O75190,Q9NZM5,P20339,Q9Y3P9,P49593,Q9NVN8,Q8WUX9,Q14195,P51608,Q9UNE7 22 +Nadp metabolic process 0.2715419648155361 0.1095248096399067 0.9127862448877616 1.0 1.0 15 Q4G0N4,P37837,P29401,P23368,Q9BQG2,Q7Z4W1 6 +Intrinsic apoptotic signaling pathway in response to dna damage 0.2669004553651485 0.1082177956691153 0.9138229289529683 1.0 1.0 24 Q9BVC6,Q9Y3B8,P09601 3 +Neuron intrinsic apoptotic signaling pathway in response to oxidative stress 0.4348140122787975 0.1067371527612182 0.9149975073169264 1.0 1.0 3 P09874,Q15233 2 +Positive regulation of cellular respiration 0.434814012278797 0.1067371527612173 0.9149975073169272 1.0 1.0 3 P55072,Q9H1K1 2 +Cell matrix adhesion 0.2645180758486383 0.1061938980894199 0.9154285121915048 1.0 1.0 30 Q9UPN3,Q13630,P20936,O75116,P14923,P35609,P49593 7 +Regulation of extrinsic apoptotic signaling pathway 0.2646637956136233 0.1050858145542407 0.9163077153225884 1.0 1.0 28 P09601,P31749 2 +Mitochondrial dna metabolic process 0.336826888326708 0.1034417044887962 0.9176124142593404 1.0 1.0 5 P49916,P09874,P04637,P36776 4 +Positive regulation of bmp signaling pathway 0.4319248826291061 0.1031911977973152 0.9178112257580016 1.0 1.0 3 Q14980,Q14318 2 +Positive regulation of immune system process 0.2497236069185861 0.1027942077834812 0.918126302432006 1.0 1.0 104 O95747,O43318,P31749,Q9H2U1,Q96ST3,P39019,P09601,Q8NE86,Q13951,P46379,Q5JRA6,Q96EY1 12 +Rho protein signal transduction 0.2650213935603355 0.1018711585067968 0.9188589430143812 1.0 1.0 24 O75116,P57105,P84095,Q9NWH9,P52565,Q9Y624,P16949 7 +Divalent inorganic cation homeostasis 0.2554691952629692 0.1004740523320311 0.9199679818187628 1.0 1.0 48 Q8TAD4,Q9Y639,Q8NE86,Q96A33,Q8NE01 5 +Myoblast differentiation 0.3204205947738613 0.0997774186254382 0.9205210358984048 1.0 1.0 7 Q16539,Q9H7N4 2 +Response to interferon alpha 0.3342970726418445 0.0997725263198164 0.920524920012068 1.0 1.0 5 P55265,P19525,P10155,P12270 4 +Regulation of translation at synapse modulating synaptic transmission 0.415365776949848 0.0994849120082058 0.9207532669408464 1.0 1.0 4 P35268,P06730 2 +Ump biosynthetic process 0.3329325970331463 0.0978320177236348 0.9220656828594284 1.0 1.0 5 P30085 1 +Pyrimidine ribonucleoside monophosphate metabolic process 0.3329325970331463 0.0978320177236348 0.9220656828594284 1.0 1.0 5 P30085 1 +Regulation of dna primase activity 0.3329101970895633 0.0978003858086695 0.9220908010227018 1.0 1.0 5 Q9BRX5,Q9Y248 2 +Nuclear membrane reassembly 0.3041419834876744 0.0977915985096736 0.9220977788249448 1.0 1.0 9 Q8WUX9,O43633 2 +Regulation of signaling receptor activity 0.2976104272266551 0.0976713840400166 0.9221932391120592 1.0 1.0 10 Q9UNH7,Q13547,P41223,Q99816,P30533,Q92769,Q15334,P07384,Q99497 9 +Inflammasome complex assembly 0.4268689057421466 0.0972097644731986 0.9225598138445904 1.0 1.0 3 Q8IXJ6,P19525 2 +Response to mechanical stimulus 0.2638371643272606 0.097075738644986 0.922666247604478 1.0 1.0 20 P42575,Q16539,P14923,Q15149,Q9Y624,P58546,O95999,Q96SI9,Q8N2K0 9 +Establishment of lymphocyte polarity 0.4125722543352729 0.0961136999175636 0.9234302707212828 1.0 1.0 4 Q96L92,Q14160,P35579 3 +Erythrocyte homeostasis 0.2603487876130019 0.0958144133259166 0.9236679698498818 1.0 1.0 32 Q16539,P39019,P09601,P40763,P18074,P42574,Q9UII2,Q9NRK6,P62753 9 +Negative regulation of viral life cycle 0.350902527075806 0.0955889537352796 0.923847038666632 1.0 1.0 2 Q14258 1 +Negative regulation of viral entry into host cell 0.350902527075806 0.0955889537352796 0.923847038666632 1.0 1.0 2 Q14258 1 +Cerebellar cortex development 0.2890016335922278 0.094346260409128 0.9248341032790656 1.0 1.0 11 P48444,P58546,Q02750,O14949,Q92989 5 +T cell activation 0.2537712141124069 0.0934285421443806 0.92556311632892 1.0 1.0 57 P35268,P31749,P78310,P02786,Q92542,Q08722,Q9UJZ1,Q13951,Q08209,P26038,P32119,P40763,P42574,P62753,Q96EY1 15 +Positive regulation of actin filament bundle assembly 0.2648965313043554 0.0924389780725996 0.9263492719622756 1.0 1.0 14 O75116,O95429,P49593 3 +Response to endoplasmic reticulum stress 0.2452302721829355 0.0923827056310656 0.9263939795702318 1.0 1.0 79 P55145,P57088,Q8TCJ2,Q9Y5P4,O76024,Q9BUN8,Q13217,Q96A33,P46379,Q04323,Q9Y3C8,Q96HY6,P62333,Q9UNE7,Q9NYU2,Q9BS26 16 +Maintenance of protein location in nucleus 0.3067396185467805 0.0922298531660329 0.9265154197260974 1.0 1.0 8 O94901 1 +Muscle cell differentiation 0.2530800954619023 0.0914286875665238 0.9271519678231604 1.0 1.0 58 O75844,P31749,Q96PU8,P78310,Q08209,Q9UGN5,P58546,P35609,P51608,P42574 10 +Protein depolymerization 0.2509684553033161 0.0913539260620845 0.9272113702788812 1.0 1.0 37 Q6IBS0,O00139,Q12792,Q8WWK9,Q99661,Q9BPX3,P58546,P35609,P16949 9 +Actomyosin structure organization 0.2516414707033659 0.0883346878700688 0.9296106697701596 1.0 1.0 44 O75116,Q07157,Q15149,Q9NQW6,Q9NWH9,Q15942,Q08722,Q9H0H5,P16949,Q9Y624,P35609,O95429,P49593 13 +Pentose phosphate shunt 0.3121832605504714 0.0870999126216473 0.930592094841026 1.0 1.0 7 P37837 1 +Negative regulation of mitochondrial fusion 0.4167569519682197 0.0860883856439698 0.9313961562607268 1.0 1.0 3 Q99536,P02786 2 +Regulation of microtubule polymerization or depolymerization 0.2599581979664226 0.0860843012824578 0.9313994030566282 1.0 1.0 26 P04350,Q8WWK9,Q9NWH9,P51608,P16949,P29372 6 +Rhythmic behavior 0.4023026245542201 0.0844705447778098 0.9326823209838176 1.0 1.0 4 P42345,P54802 2 +Pentose metabolic process 0.4017789749224236 0.0839080602830096 0.9331295309842128 1.0 1.0 4 Q9UKK9 1 +Negative regulation of cellular protein catabolic process 0.2586365683107696 0.0838093154360625 0.9332080414334156 1.0 1.0 29 Q9NZM5,P46379,Q04323,P60520,Q96HY6 5 +Regulation of cell cell adhesion 0.2508800221083255 0.0826096439545726 0.9341619327222184 1.0 1.0 45 P49593,P31749,Q96EY1 3 +Immune system development 0.2449308127834416 0.082379453376546 0.934344974338035 1.0 1.0 140 Q03164,Q9H2U1,Q9NRK6,P18858,O75844,Q14004,O00625,P62805,Q96ST3,Q9NQW6,Q96T37,P18074,Q96EY1,P35268,P39019,P40763,Q9UII2,P42574,Q13043,Q04760,P13051,Q13951,O95470,P04179 24 +Motor neuron apoptotic process 0.3404332129963836 0.0822997804818825 0.9344083289798576 1.0 1.0 2 O75312 1 +Positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway 0.3404332129963835 0.0822997804818822 0.9344083289798576 1.0 1.0 2 Q07812 1 +Regulation of establishment or maintenance of cell polarity 0.3167028199566105 0.0817386194097685 0.9348545672467736 1.0 1.0 6 O75116,A0MZ66,Q9NUQ9,Q15334,Q14254 5 +Positive regulation of transcription by rna polymerase i 0.2602442059608758 0.0817126471925675 0.9348752209886004 1.0 1.0 14 Q8TED0,Q9H583,Q9NWS0 3 +Regulation of cytosolic calcium ion concentration 0.2583882307461078 0.0811866752271752 0.9352934961621384 1.0 1.0 20 Q9Y639 1 +Peptidyl cysteine modification 0.3194795807733999 0.0801255056611778 0.9361374373767816 1.0 1.0 5 P20340,P04406,P30048,Q99497 4 +Cellular detoxification of aldehyde 0.3194795807733961 0.0801255056611731 0.9361374373767852 1.0 1.0 5 P10768,Q8TC12,P14550,Q99497 4 +Synaptonemal complex organization 0.3149643635596381 0.0794411773221678 0.9366817173479852 1.0 1.0 6 P46379 1 +Er overload response 0.3973644250396119 0.0792845341059202 0.9368063075697431 1.0 1.0 4 Q96A33 1 +Positive regulation of dna binding 0.2591483624599985 0.0792756712462047 0.9368133569200644 1.0 1.0 14 Q96HY6,P07305 2 +Regulation of chromosome segregation 0.2571194256431806 0.0791895835460953 0.9368818296996364 1.0 1.0 30 Q7Z5K2,P50748,Q99661,P19784,Q14671,Q00839,P14635 7 +Protein k48 linked deubiquitination 0.2870887921790874 0.0789281907605243 0.9370897401983234 1.0 1.0 10 Q8TEY7 1 +Poly a plus mrna export from nucleus 0.2980023042049468 0.0788151020974626 0.9371796916787364 1.0 1.0 8 Q86U42 1 +Positive regulation of transcription by rna polymerase iii 0.297358392151565 0.077879121859245 0.9379242073038814 1.0 1.0 8 O60264,P35659 2 +Lung cell differentiation 0.4084507042253557 0.0777716579406407 0.9380096918319716 1.0 1.0 3 P09960,P35222 2 +Regulation of oligodendrocyte differentiation 0.3134490238611674 0.0774752955415489 0.9382454434932708 1.0 1.0 6 P35222,Q13547,O14744,O75083,P42345 5 +Microtubule cytoskeleton organization involved in mitosis 0.2497160534092833 0.0774711341535946 0.9382487538510016 1.0 1.0 60 Q8WUX9,Q02241,Q9HBM1,O00139,Q9BZD4,Q9H0H5,Q00839,P51608,P16949,P14635,O43663 11 +Cell fate specification 0.3947493188874876 0.0766446058377038 0.9389062729674468 1.0 1.0 4 Q96KQ7 1 +Actin filament depolymerization 0.2570731871605612 0.0752058563102144 0.9400509248909876 1.0 1.0 19 P35609,Q6IBS0,Q12792,P58546 4 +Response to antibiotic 0.2951080770730051 0.0746642633241125 0.9404818420110584 1.0 1.0 8 P62829,O60341,P07900,P42574,Q96KQ7 5 +Glycosylation 0.2546520714243118 0.0744093447363501 0.9406846733939216 1.0 1.0 32 Q8TCJ2,O60762,O60502,P04844,O15294,Q9NYU2 6 +Response to activity 0.2644598445797519 0.0742849271559513 0.9407836702794424 1.0 1.0 13 Q9Y376,Q9UDX5 2 +Negative regulation of endoplasmic reticulum unfolded protein response 0.3108650436568263 0.0742014162046949 0.940850118991233 1.0 1.0 6 Q96HY6 1 +Inner ear auditory receptor cell differentiation 0.3139871441649723 0.0736271745287899 0.9413070476715002 1.0 1.0 5 O14745 1 +Establishment or maintenance of cytoskeleton polarity 0.390719900996218 0.0727190975114727 0.9420296511662823 1.0 1.0 4 Q14008,Q99661 2 +Protein homotetramerization 0.2560405936292489 0.0724201141090881 0.942267578077608 1.0 1.0 16 Q04837,P04179,Q9NPJ3,Q99797 4 +Protein maturation by protein folding 0.308494923622379 0.0712847486033876 0.9431711331995408 1.0 1.0 6 P27797,O76024,O00170 3 +Regulation of protein depolymerization 0.2546507161656772 0.0710139229930957 0.9433866745213304 1.0 1.0 28 Q6IBS0,Q12792,Q8WWK9,P35241,Q92974,Q9BPX3,P58546,P35609,P29372 9 +Neural crest cell migration 0.4001444564824871 0.0701687876905825 0.9440593168860856 1.0 1.0 3 Q9ULV4,P60953 2 +Lamellipodium organization 0.254921378120173 0.0698079401187201 0.9443465272972162 1.0 1.0 25 P53365,Q6IBS0,Q13596 3 +Regulation of defense response to virus by host 0.2984246545111275 0.0683733072106732 0.9454884698525352 1.0 1.0 7 Q96ST3 1 +Postreplication repair 0.2741760231800078 0.0675155071208596 0.946171317296131 1.0 1.0 11 P55072,Q9Y2S7,P12004,Q9C0J8,Q9NZJ0,Q13404,P28340,Q15004,P43246,P61088 10 +Response to muramyl dipeptide 0.3847845385855538 0.0672454687901981 0.9463862881581796 1.0 1.0 4 Q16539 1 +Regulation of ire1 mediated unfolded protein response 0.2971886673824093 0.0668376310354335 0.946710965141683 1.0 1.0 7 Q96HY6 1 +Cytoplasmic translational elongation 0.3841076832280073 0.066644265517239 0.9468649052689986 1.0 1.0 4 P05387 1 +Regulation of microtubule based process 0.2486464568632574 0.0664887519685594 0.9469887125231056 1.0 1.0 57 Q9UPN3,P04350,Q8WUX9,Q96PK6,P57076,O75116,O43633,Q7KZI7,Q8WWK9,Q9NWH9,Q92974,Q00839,P51608,P16949,P29372 15 +Regulation of short term neuronal synaptic plasticity 0.3256317689530621 0.0664703670439661 0.9470033491912172 1.0 1.0 2 Q96A49 1 +Neutrophil homeostasis 0.324909747292412 0.0657823861139786 0.947551079702571 1.0 1.0 2 P09429 1 +Neutrophil clearance 0.324909747292412 0.0657823861139786 0.947551079702571 1.0 1.0 2 P09429 1 +Cortical cytoskeleton organization 0.2524824641962254 0.0657703503020831 0.9475606621392684 1.0 1.0 22 O75116,P84095,P27797,Q9Y490,Q15149,Q9NQW6,Q9H0H5,Q14651 8 +Dicarboxylic acid biosynthetic process 0.2954792043399519 0.064752713107957 0.9483708918600644 1.0 1.0 7 P11586,P00367,Q6UB35,P17174,O94925,P00505 6 +Negative regulation of telomere maintenance via telomere lengthening 0.2857262243690773 0.0621894210491024 0.9504119869637476 1.0 1.0 8 Q9NVN8 1 +Negative regulation of intracellular transport 0.2510331928107498 0.0617309579426456 0.9507770861021654 1.0 1.0 15 O95429,Q9GZP9,P53367 3 +Positive regulation of posttranscriptional gene silencing 0.2578279426077638 0.061610346966759 0.9508731369103018 1.0 1.0 13 Q14671,P40763,Q04637,P36507 4 +Protein nitrosylation 0.3191335740072136 0.060546793326465 0.9517201484979873 1.0 1.0 2 P04406 1 +Neurotrophin trk receptor signaling pathway 0.301208980491879 0.0600874502305122 0.9520859851682086 1.0 1.0 5 P42574 1 +Dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest 0.3760838150289134 0.0598677095030511 0.9522609978310026 1.0 1.0 4 O96017,P61254,P42575 3 +Dna damage response signal transduction resulting in transcription 0.3760838150289071 0.0598677095030461 0.9522609978310066 1.0 1.0 4 O96017,P61254,Q9UNS2 3 +Positive regulation of necrotic cell death 0.3760838150289068 0.0598677095030458 0.9522609978310068 1.0 1.0 4 Q9NZI8,P55212,P00403 3 +Regulation of nadp metabolic process 0.3760838150289053 0.0598677095030447 0.9522609978310076 1.0 1.0 4 P48163,P23368,P18669 3 +Import into nucleus 0.2457262928899569 0.0565791698041623 0.9548804280475937 1.0 1.0 60 Q99623,O15397,P31749,Q16539,Q14978,P14923,P54619,O14787,Q9UI26,Q08209,Q13043,Q7Z4Q2,P40763,Q9UHD1,Q9BVL2,Q5SRE5,P52294,O00505 18 +Negative regulation of telomere maintenance via telomerase 0.2882374316340305 0.0564157171869263 0.9550106363912604 1.0 1.0 7 Q9NVN8 1 +Response to xenobiotic stimulus 0.2456608323343161 0.0562469673166492 0.9551450658508084 1.0 1.0 60 O43169,P09601,P04844,P33527,P46100,P42574,P49593 7 +Positive regulation of signaling receptor activity 0.2970726418503795 0.0561620027635556 0.9552127507650132 1.0 1.0 5 Q92769,P41223,Q99497,Q13547 4 +Positive regulation of atp dependent activity 0.2489141970667166 0.0560472683417862 0.9553041516228068 1.0 1.0 20 Q04837,Q5JTV8,Q8NFQ8,P60520 4 +Positive regulation of cell cycle 0.2397494885658885 0.0558700710242364 0.955445313438272 1.0 1.0 79 O75832,Q02241,P62244,P31749,Q96ST3,Q7Z7K6,Q9H0H5,P46100,Q7L2J0,Q96HY6,P51608,P14635 12 +Mechanoreceptor differentiation 0.2876108281979783 0.0557314691959087 0.955555729660294 1.0 1.0 7 Q14651,O14745,P54802 3 +Viral genome replication 0.2436221008740379 0.0545563507648631 0.9564919139787016 1.0 1.0 43 P56545,O95793,Q15366,P11940,Q9H6S0,P20339,P35659 7 +Ire1 mediated unfolded protein response 0.2793565275038343 0.0545534418058863 0.9564942315407832 1.0 1.0 8 Q96HY6 1 +Positive regulation of atp metabolic process 0.2952656306469102 0.0545150952298624 0.9565247822193056 1.0 1.0 5 P55072,P06733,Q13131,P00403 4 +Positive regulation of nucleotide metabolic process 0.2952656306469102 0.0545150952298624 0.9565247822193056 1.0 1.0 5 P55072,P06733,Q13131,P00403 4 +Synaptic vesicle priming 0.366348880733797 0.0524863370153648 0.9581411818114868 1.0 1.0 4 O95721 1 +Cellular response to antibiotic 0.3759479956663016 0.051833610057395 0.9586612745844758 1.0 1.0 3 P61160,P62829 2 +Glutamate catabolic process 0.3755868544600891 0.0516003403338794 0.958847148155708 1.0 1.0 3 P00505,P17174 2 +Acidic amino acid transport 0.2730020931992167 0.0514840295917764 0.9589398275133943 1.0 1.0 9 O75915 1 +Protein localization to cytoplasmic stress granule 0.2902170170172655 0.0514800730280854 0.9589429802137468 1.0 1.0 6 P31483,P05455,P67809 3 +3 utr mediated mrna stabilization 0.2828209764918567 0.0506921795733058 0.9595708084352748 1.0 1.0 7 Q92615,Q16539,Q13148,Q13151,P07910,P98175 6 +Ubiquitin dependent erad pathway 0.2479703668229224 0.0498341767550291 0.9602545313960068 1.0 1.0 31 Q8TCJ2,O76024,Q9BUN8,Q96A33,P46379,Q9UNE7 6 +Ruffle organization 0.2440063780973796 0.0490560514633934 0.96087462706253 1.0 1.0 14 P84095,Q9UHB6,P35241,P53365,O95429 5 +Oocyte maturation 0.3576589595375805 0.0466361993453767 0.962803180500938 1.0 1.0 4 Q8IXJ6,Q15645,P30153 3 +Myeloid leukocyte activation 0.2490483602897707 0.0465420519402104 0.9628782177817676 1.0 1.0 13 P09601 1 +Nucleosome assembly 0.245701850631113 0.0462622795882538 0.9631012036297232 1.0 1.0 33 P10412,P16403,Q9H0U9,P07305,P46100,Q9UER7,Q9P0M6 7 +Rab protein signal transduction 0.3562138728323777 0.0457280729110846 0.9635269882607024 1.0 1.0 4 Q15286,Q14964,P31150 3 +Negative regulation of nik nf kappab signaling 0.3658360418923778 0.0457181298962104 0.963534913350323 1.0 1.0 3 O00571,O43657 2 +Regulation of dna dependent dna replication 0.243947980884713 0.0456362211522905 0.9636001989308768 1.0 1.0 21 P49916,O75844,Q9BRX5,Q04837,P46100,Q9Y248 6 +Protein folding 0.2412628437354342 0.0454973896995679 0.9637108554638688 1.0 1.0 101 Q9BS26,Q9Y3C6,O75190,P04792,O76024,Q13217,Q96A33,O95302,O14737,O95429,O15212,Q9NYU2,Q96EY1 13 +Positive regulation of maintenance of sister chromatid cohesion 0.364752618273744 0.0451127294983216 0.9640174550809132 1.0 1.0 3 Q8IY18,O75367 2 +Hematopoietic stem cell homeostasis 0.3540462427745745 0.0443995008704207 0.9645859595057624 1.0 1.0 4 Q9NVX2,P55265,Q14157 3 +Protein containing complex disassembly 0.2378375280144956 0.043867937114944 0.9650096731617676 1.0 1.0 79 Q8WUX9,O75844,Q6IBS0,O00139,O43633,Q12792,Q8WWK9,Q9UBB9,Q99661,Q14197,Q9BPX3,P58546,P35609,O95721,P16949,P17096 16 +Myeloid cell homeostasis 0.2392937003175786 0.0434579746700258 0.9653364642102708 1.0 1.0 37 Q16539,P39019,Q92542,P09601,Q9NRK6,P40763,P42574,Q9UII2,P18074,P62753 10 +Response to toxic substance 0.2424784234352966 0.0432143270214999 0.9655306844462376 1.0 1.0 46 Q7Z5K2,P00374,P07196,Q15165,P04179,Q13867,Q16881,Q5VT66 8 +Cellular extravasation 0.281185780856137 0.0430422108352566 0.9656678856340136 1.0 1.0 5 Q9Y624 1 +Translesion synthesis 0.2737793851717748 0.042076373974884 0.9664378143240532 1.0 1.0 7 P55072,Q9Y2S7,P12004,Q9NZJ0,P28340,Q15004 6 +Ribosomal large subunit biogenesis 0.2437516737726454 0.0412270049858667 0.9671149251043634 1.0 1.0 54 P42766,Q969S3,P18077,Q9NZM5,O95478,Q9NWT1 6 +Regulation of proteasomal protein catabolic process 0.2412612069726624 0.0411802007432071 0.9671522377999412 1.0 1.0 63 O00487,P31749,Q9NZM5,P46379,P60520,Q96HY6,Q9UNE7 7 +Intrinsic apoptotic signaling pathway in response to hypoxia 0.357168652943297 0.0411319792462831 0.9671906804165328 1.0 1.0 3 P06733,P04637 2 +Pigmentation 0.2507246376811585 0.0405268716651283 0.9676730841445504 1.0 1.0 12 Q86YV9,Q9BXS5,P63244,P62820,O14617,Q13561,O43747,Q07812,Q96AX1,P48444,P04179 11 +Trachea development 0.3442919075144539 0.0389037017392983 0.9689671652437872 1.0 1.0 4 Q02750,P27361,P35222 3 +Animal organ formation 0.3442919075144539 0.0389037017392983 0.9689671652437872 1.0 1.0 4 Q02750,P27361,P35222 3 +Trachea morphogenesis 0.3442919075144539 0.0389037017392983 0.9689671652437872 1.0 1.0 4 Q02750,P27361,P35222 3 +Trachea formation 0.3442919075144539 0.0389037017392983 0.9689671652437872 1.0 1.0 4 Q02750,P27361,P35222 3 +Pyrimidine nucleobase biosynthetic process 0.269524648173705 0.0384123981730507 0.9693588759656148 1.0 1.0 7 Q9NRF8,P30085 2 +Negative regulation of response to endoplasmic reticulum stress 0.2433378243226917 0.0377593264959125 0.9698795739828696 1.0 1.0 13 Q96HY6,Q04323 2 +Negative regulation of dna biosynthetic process 0.2625186036527261 0.0374429922586096 0.9701317938226236 1.0 1.0 8 Q9NVN8 1 +T helper 1 type immune response 0.3486506286974535 0.0371718811815309 0.9703479586782996 1.0 1.0 3 P42345 1 +T helper 1 cell differentiation 0.3486506286974535 0.0371718811815309 0.9703479586782996 1.0 1.0 3 P42345 1 +Thyroid gland development 0.3441675695196761 0.0352916709174165 0.9718471648402508 1.0 1.0 3 Q02750,P27361 2 +Plasma membrane to endosome transport 0.3438064283134679 0.0351460723076735 0.9719632636978972 1.0 1.0 3 Q15286,P61020 2 +Central nervous system neuron axonogenesis 0.3401950162513498 0.0337368414197369 0.9730870004792432 1.0 1.0 3 P07900,P08238 2 +Hemostasis 0.2388431364597188 0.0335167072014308 0.9732625428967504 1.0 1.0 21 Q16539,Q9Y490,P04792,Q9Y624,Q9BWH2 5 +Cell communication by electrical coupling involved in cardiac conduction 0.338750451426504 0.0331965132261671 0.9735178786340934 1.0 1.0 3 P17612,P05023 2 +Neutral amino acid transport 0.3387117583538529 0.0331822207379046 0.97352927611073 1.0 1.0 3 P08195 1 +Cytosolic calcium ion transport 0.2386201560685633 0.0330087439787853 0.97366761475565 1.0 1.0 21 Q8NE86 1 +Negative regulation of autophagosome assembly 0.3369447453954446 0.0325394315172161 0.9740418708636271 1.0 1.0 3 O75396,Q96KQ7 2 +Photoperiodism 0.2645464401879286 0.0323590874657961 0.9741856888608584 1.0 1.0 5 P04637,Q13330,P62136,Q9BWF3 4 +Entrainment of circadian clock 0.2645464401879286 0.0323590874657961 0.9741856888608584 1.0 1.0 5 P04637,Q13330,P62136,Q9BWF3 4 +Regulation of cellular carbohydrate catabolic process 0.2645464401879287 0.0323590874657961 0.9741856888608584 1.0 1.0 5 P18669,P04637,P62136,Q14108 4 +Cellular response to interferon alpha 0.334055615745754 0.0315295382720674 0.9748472357157324 1.0 1.0 3 P10155,P12270 2 +Negative regulation of microtubule polymerization 0.2648192457438725 0.0312412882610925 0.9750771127009674 1.0 1.0 6 P04350,P16949 2 +Mitotic cell cycle 0.2469170281900508 0.0311179163029835 0.9751755014447164 1.0 1.0 266 P68371,P04350,Q02241,Q9NY61,Q53EZ4,Q08209,Q9NVX2,Q9H6S0,Q06323,P62753,P14635,P18858,O75844,Q53HL2,O60264,Q14141,Q14004,Q96ST3,Q8WWK9,Q8TBC4,Q9NQW6,Q99661,Q9BZD4,Q9H7N4,P35244,Q7L2J0,Q13432,P18074,Q9NTI5,Q9HBM1,P20936,P31749,P50748,O43768,Q16763,Q9H0H5,Q99986,Q9NZM5,Q99640,Q9BPX3,Q00839,Q07864,Q8WUX9,P42695,O43663,Q7Z5K2,O75116,O43633,Q9BRX5,Q9BSJ2,Q96CW5,O14745,P46100,O00139,P51608,Q86XL3,P16949,P18583 58 +Regulation of glycogen catabolic process 0.2642599277978265 0.0305562729629888 0.9756234149714548 1.0 1.0 2 P62136 1 +Striated muscle contraction 0.2320822041776073 0.0296563756799522 0.9763411037687312 1.0 1.0 14 P14923,P15924,P10253 3 +Scf dependent proteasomal ubiquitin dependent protein catabolic process 0.2580411998554394 0.0289448996822488 0.976908535840449 1.0 1.0 5 Q13616,Q93034,P63208,Q13617 4 +Regulation of lipoprotein metabolic process 0.3257493680028835 0.0288968470955665 0.9769468602265314 1.0 1.0 3 Q9H2M9,P04062 2 +Regulation of protein lipidation 0.3257493680028835 0.0288968470955665 0.9769468602265314 1.0 1.0 3 Q9H2M9,P04062 2 +Transferrin transport 0.3189089660435144 0.027939284407558 0.9777105762365031 1.0 1.0 4 P02786 1 +Positive regulation of extrinsic apoptotic signaling pathway 0.2497483521520151 0.0279005261766301 0.9777414887797244 1.0 1.0 9 Q13043,P62136 2 +Maintenance of protein localization in endoplasmic reticulum 0.3221379559407732 0.0278705292162439 0.9777654135874811 1.0 1.0 3 P24390,O43292 2 +Protein retention in er lumen 0.3221379559407732 0.0278705292162439 0.9777654135874811 1.0 1.0 3 P24390,O43292 2 +Regulation of nuclear transcribed mrna poly a tail shortening 0.3172989252837784 0.0273884325103488 0.9781499243087172 1.0 1.0 4 P11940 1 +Mitochondrial acetyl coa biosynthetic process from pyruvate 0.3199711087034963 0.0272872474916571 0.9782306281099508 1.0 1.0 3 P11177,P09622 2 +Negative regulation of oxidative stress induced neuron death 0.3164739884393084 0.0271122416447617 0.9783702109300024 1.0 1.0 4 Q15233,Q99497,P35222 3 +Cellular response to calcium ion 0.2465604634322999 0.0268339228655079 0.978592196419088 1.0 1.0 10 P46940,P35611,Q9NXV6,Q92542,Q9Y696,O75131,Q6NUK1,Q13131,Q99829 9 +Negative regulation of smoothened signaling pathway 0.3163596966413823 0.0263671922948302 0.9789644618032388 1.0 1.0 3 P17612,P55072 2 +Positive regulation of oligodendrocyte differentiation 0.313222543352608 0.0260627103351897 0.9792073197937224 1.0 1.0 4 O14744,P42345,Q13547 3 +Cellular response to fatty acid 0.314192849404114 0.025845351871836 0.9793806883540686 1.0 1.0 3 Q15120,P11802 2 +Collagen biosynthetic process 0.3131094257854808 0.0255926690946665 0.9795822333714532 1.0 1.0 3 P08670,P50454 2 +Cellular pigmentation 0.2502712477395987 0.0247103510737693 0.9802859986396044 1.0 1.0 7 Q9BXS5,O14617,P62820,Q13561,O43747,Q96AX1 6 +Cardiac muscle contraction 0.2335447582510249 0.0244885969706686 0.9804628792880457 1.0 1.0 13 P14923,P15924,P10253 3 +Positive regulation of nucleotide biosynthetic process 0.3062939471248914 0.0240253440073673 0.980832392944882 1.0 1.0 4 P06733 1 +Positive regulation of atp biosynthetic process 0.3062939471248914 0.0240253440073673 0.980832392944882 1.0 1.0 4 P06733 1 +Hypothalamus development 0.2468377303939288 0.0239597630262297 0.9808847039388188 1.0 1.0 5 Q07812,Q15042,O75569,O14949 4 +Ribosomal large subunit assembly 0.2343283171321376 0.0234462946314386 0.9812942773667708 1.0 1.0 20 Q8TDN6,P63173,P62750,Q9NZM5,Q7L2E3,Q9NVX2,P05388 7 +Protein dna complex assembly 0.2383831683314862 0.0232474939883094 0.981452854106146 1.0 1.0 48 O15160,O60264,P10412,P16403,P62805,P50748,Q9H0U9,Q7Z7K6,Q9NWS0,P07305,P62333,P46100,Q9UER7,Q9P0M6 14 +Mitochondrial genome maintenance 0.2477396021699732 0.0232334447449554 0.9814640607536363 1.0 1.0 7 P49916,P04637,O60313,Q8NFG4,P36776,P09874 6 +Muscle structure development 0.2324835619561568 0.0230406764992869 0.9816178263977346 1.0 1.0 82 O75844,P31749,Q96PU8,P78310,Q08209,P80723,Q9UGN5,P42574,P35609,P51608,P58546,P15924 12 +Response to tumor cell 0.2975063661176579 0.0218019927208314 0.9826059046044288 1.0 1.0 4 P09429,P32119 2 +Cd40 signaling pathway 0.2969653179190786 0.0216773802665514 0.9827053074653525 1.0 1.0 4 P35232,Q99623,Q9BXW9 3 +Mrna 3 splice site recognition 0.2406938923021326 0.0216645365781911 0.9827155528399464 1.0 1.0 5 Q9ULR0,Q12874,Q15637,Q15428 4 +Regulation of wnt signaling pathway 0.233074755816213 0.0212657635488287 0.9830336543897212 1.0 1.0 37 Q8IZT6,Q16539,P14923,Q13283,O14745,Q9NVX2,Q13043,P52294 8 +Negative regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway 0.2460495039979881 0.0209520661427772 0.983283892948102 1.0 1.0 6 O76024 1 +Cell redox homeostasis 0.2344202898550715 0.0207509626328818 0.9834443154550074 1.0 1.0 12 Q96HE7,P27695,P00390,P30041,O76003,P09622,P30048,P32119,P30044,Q16881,Q9BS26 11 +Regulation of stem cell population maintenance 0.2824124232574885 0.0203829509959914 0.9837378841603164 1.0 1.0 3 A5YKK6,Q15061 2 +Viral translational termination reinitiation 0.2447577729573351 0.0203698913470555 0.9837483020895929 1.0 1.0 6 P56537,Q9Y262,Q14152,O75821,O15371 5 +Apical protein localization 0.2887869124357426 0.0199538346452995 0.9840801998407558 1.0 1.0 4 P18085 1 +Negative regulation of cellular catabolic process 0.2325742254162147 0.0195195403833735 0.9844266490405358 1.0 1.0 81 Q9H2U1,P11940,P10619,P19784,P62081,Q96HY6,P31749,Q16539,Q04637,Q9NWH9,Q9H074,Q9NZM5,P40763,P60520,Q00839,P09601,Q9H814,P46379,Q04323,O15294 20 +Heart valve development 0.2861271676300632 0.0194545824341851 0.9844784681453138 1.0 1.0 4 O75116,Q9ULT8,P42345 3 +Regulation of protein polyubiquitination 0.2403937393766405 0.0193350741212974 0.9845738040505648 1.0 1.0 7 P61088 1 +Regulation of cellular response to hypoxia 0.2815173489651377 0.018655210227504 0.9851161590905676 1.0 1.0 4 O75116 1 +Trophectodermal cell differentiation 0.2271354832457369 0.0175612828926082 0.9859888436860956 1.0 1.0 5 A5YKK6 1 +Regulation of calcineurin mediated signaling 0.2692401293965396 0.0168943786287522 0.9865208773327416 1.0 1.0 4 Q9UHD1 1 +Regulation of the force of heart contraction 0.2691473988439341 0.0168829315284275 0.9865300094948956 1.0 1.0 4 P16615,P05023,P10253 3 +Cell killing 0.2296530192562862 0.0145190129415519 0.9884159107282916 1.0 1.0 20 P05204,P39019,P81605 3 +Negative regulation of erk1 and erk2 cascade 0.2219115246253035 0.0142205166402502 0.9886540517295191 1.0 1.0 15 P57105,Q8IV63,O14745,Q96S59 4 +Hydrogen peroxide catabolic process 0.2337427745664759 0.0140379478237313 0.9887997060297128 1.0 1.0 4 P30044,P30048,P32119 3 +Translational termination 0.2253164556961972 0.0129697471548367 0.989651929104107 1.0 1.0 7 P63241,P61221,P15170,Q14197,P13798,Q92900 6 +Regulation of endocytosis 0.2331198413037882 0.0125892389594894 0.9899555059261986 1.0 1.0 35 P57105,Q8NBU5,P30533,Q96T51,Q08209,Q13432,P20339 7 +Dephosphorylation 0.2339898032234304 0.0104788817345431 0.9916392150618752 1.0 1.0 74 O75116,Q9H0C8,Q01968,O95429,Q15750,O43768,Q10713,Q9NQG5,Q86XL3,Q9H0R4,Q08209,Q8IV63,Q9H0P0,Q92797,P04899,Q9NX62,P49593 17 +Negative regulation of wnt signaling pathway 0.2189912738582438 0.0090113041187172 0.9928101168785092 1.0 1.0 16 Q16539,O14745,Q13043 3 +Glutathione metabolic process 0.22378446715604 0.0061998154386585 0.9950532946716928 1.0 1.0 19 O75915,Q04760 2 +Dna geometric change 0.2335101556939519 0.0021251194752183 0.99830440125712 1.0 1.0 50 O94761,Q04837,Q2NKX8,P46100,P17096 5 +Negative regulation of protein modification by small protein conjugation or removal 0.2302837389151706 0.001248899461088 0.9990035226610454 1.0 1.0 31 Q9NVN8,P62841,Q04323,P31749 4 +Adherens junction organization 0.2092035010610915 1.714048152450463e-05 0.9999863238744277 1.0 1.0 12 Q07157,Q15149,P15924 3 diff --git a/msigdb_gobp/selections.json b/msigdb_gobp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..ffa229b6c021191c77976607e3b2542f7849efd4 --- /dev/null +++ b/msigdb_gobp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["10 formyltetrahydrofolate metabolic process", "2 oxoglutarate metabolic process", "2fe 2s cluster assembly", "3 phosphoadenosine 5 phosphosulfate biosynthetic process", "3 phosphoadenosine 5 phosphosulfate metabolic process", "3 utr mediated mrna destabilization", "3 utr mediated mrna stabilization", "5 phosphoribose 1 diphosphate metabolic process", "5s class rrna transcription by rna polymerase iii", "Abscission", "Acetyl coa biosynthetic process", "Acetyl coa biosynthetic process from pyruvate", "Acetyl coa metabolic process", "Acid secretion", "Acidic amino acid transport", "Acrosome assembly", "Actin crosslink formation", "Actin cytoskeleton reorganization", "Actin filament based movement", "Actin filament based process", "Actin filament based transport", "Actin filament bundle organization", "Actin filament depolymerization", "Actin filament network formation", "Actin filament organization", "Actin filament polymerization", "Actin filament reorganization", "Actin filament severing", "Actin mediated cell contraction", "Actin modification", "Actin myosin filament sliding", "Actin nucleation", "Actin polymerization dependent cell motility", "Actin polymerization or depolymerization", "Action potential", "Activated t cell proliferation", "Activation induced cell death of t cells", "Activation of adenylate cyclase activity", "Activation of cysteine type endopeptidase activity", "Activation of cysteine type endopeptidase activity involved in apoptotic process", "Activation of cysteine type endopeptidase activity involved in apoptotic process by cytochrome c", "Activation of gtpase activity", "Activation of immune response", "Activation of innate immune response", "Activation of nf kappab inducing kinase activity", "Activation of phospholipase c activity", "Activation of phospholipase d activity", "Activation of protein kinase activity", "Activation of protein kinase b activity", "Activation of protein kinase c activity", "Activation of store operated calcium channel activity", "Activin receptor signaling pathway", "Actomyosin contractile ring organization", "Actomyosin structure organization", "Acute inflammatory response", "Acute inflammatory response to antigenic stimulus", "Acute phase response", "Acyl carnitine transmembrane transport", "Acylglycerol homeostasis", "Adaptation of signaling pathway", "Adaptive immune response", "Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains", "Adaptive thermogenesis", "Adenosine metabolic process", "Adenosine to inosine editing", "Adenylate cyclase activating adrenergic receptor signaling pathway", "Adenylate cyclase activating adrenergic receptor signaling pathway involved in heart process", "Adenylate cyclase activating dopamine receptor signaling pathway", "Adenylate cyclase activating g protein coupled receptor signaling pathway", "Adenylate cyclase inhibiting dopamine receptor signaling pathway", "Adenylate cyclase inhibiting g protein coupled receptor signaling pathway", "Adenylate cyclase modulating g protein coupled receptor signaling pathway", "Adherens junction assembly", "Adherens junction maintenance", "Adherens junction organization", "Adhesion of symbiont to host", "Adhesion of symbiont to host cell", "Adiponectin activated signaling pathway", "Adipose tissue development", "Adp biosynthetic process", "Adp metabolic process", "Adp transport", "Adrenergic receptor signaling pathway", "Adult behavior", "Adult locomotory behavior", "Aerobic respiration", "Aggrephagy", "Aggresome assembly", "Aging", "Alanine catabolic process", "Alanine transport", "Alcohol biosynthetic process", "Alcohol catabolic process", "Alcohol metabolic process", "Aldehyde biosynthetic process", "Aldehyde catabolic process", "Alditol biosynthetic process", "Alditol catabolic process", "Alditol metabolic process", "Alditol phosphate metabolic process", "Alkanesulfonate metabolic process", "Allantoin metabolic process", "Alpha amino acid catabolic process", "Alpha amino acid metabolic process", "Alpha beta t cell activation", "Alpha beta t cell differentiation", "Alpha beta t cell proliferation", "Alpha ketoglutarate transport", "Alpha linolenic acid metabolic process", "Alternative mrna splicing via spliceosome", "Ameboidal type cell migration", "Amide biosynthetic process", "Amide transport", "Amine biosynthetic process", "Amine catabolic process", "Amine metabolic process", "Amine transport", "Amino acid activation", "Amino acid betaine biosynthetic process", "Amino acid betaine metabolic process", "Amino acid betaine transport", "Amino acid homeostasis", "Amino acid import", "Amino acid import across plasma membrane", "Amino acid neurotransmitter reuptake", "Amino acid salvage", "Amino acid transmembrane transport", "Amino acid transport", "Amino sugar biosynthetic process", "Amino sugar catabolic process", "Amino sugar metabolic process", "Aminoacyl trna metabolism involved in translational fidelity", "Aminoglycan biosynthetic process", "Aminoglycan catabolic process", "Aminoglycan metabolic process", "Aminoglycoside antibiotic metabolic process", "Aminophospholipid transport", "Ammonium ion metabolic process", "Ammonium transmembrane transport", "Amp biosynthetic process", "Amp catabolic process", "Amp metabolic process", "Amp salvage", "Ampa glutamate receptor clustering", "Amygdala development", "Amyloid beta clearance", "Amyloid beta clearance by cellular catabolic process", "Amyloid beta clearance by transcytosis", "Amyloid beta formation", "Amyloid beta metabolic process", "Amyloid fibril formation", "Amyloid precursor protein biosynthetic process", "Amyloid precursor protein catabolic process", "Amyloid precursor protein metabolic process", "Anagen", "Anaphase promoting complex dependent catabolic process", "Anatomical structure formation involved in morphogenesis", "Anatomical structure homeostasis", "Anatomical structure maturation", "Androgen catabolic process", "Androgen metabolic process", "Androgen receptor signaling pathway", "Angiogenesis involved in wound healing", "Angiotensin activated signaling pathway", "Animal organ formation", "Animal organ maturation", "Animal organ morphogenesis", "Animal organ regeneration", "Anion homeostasis", "Anion transmembrane transport", "Anion transport", "Anoikis", "Anterior head development", "Anterior posterior axis specification", "Anterior posterior pattern specification", "Anterograde axonal transport", "Anterograde axonal transport of mitochondrion", "Anterograde dendritic transport", "Anterograde dendritic transport of neurotransmitter receptor complex", "Anterograde neuronal dense core vesicle transport", "Antibacterial humoral response", "Antifungal innate immune response", "Antigen processing and presentation", "Antigen processing and presentation of endogenous antigen", "Antigen processing and presentation of endogenous peptide antigen", "Antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway", "Antigen processing and presentation of exogenous antigen", "Antigen processing and presentation of exogenous peptide antigen", "Antigen processing and presentation of exogenous peptide antigen via mhc class i", "Antigen processing and presentation of exogenous peptide antigen via mhc class ii", "Antigen processing and presentation of lipid antigen via mhc class ib", "Antigen processing and presentation of peptide antigen", "Antigen processing and presentation of peptide antigen via mhc class i", "Antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii", "Antigen processing and presentation via mhc class ib", "Antigen receptor mediated signaling pathway", "Antimicrobial humoral immune response mediated by antimicrobial peptide", "Antimicrobial humoral response", "Antiviral innate immune response", "Aorta development", "Aorta morphogenesis", "Aortic valve morphogenesis", "Apical junction assembly", "Apical protein localization", "Apolipoprotein a i mediated signaling pathway", "Apoptotic cell clearance", "Apoptotic chromosome condensation", "Apoptotic dna fragmentation", "Apoptotic mitochondrial changes", "Apoptotic process involved in blood vessel morphogenesis", "Apoptotic process involved in development", "Apoptotic process involved in heart morphogenesis", "Apoptotic process involved in morphogenesis", "Apoptotic signaling pathway", "Appendage development", "Appendage morphogenesis", "Arachidonic acid metabolic process", "Arachidonic acid secretion", "Arf protein signal transduction", "Arginine catabolic process", "Arginine metabolic process", "Aromatic amino acid family catabolic process", "Aromatic amino acid family metabolic process", "Aromatic amino acid transport", "Arp2 3 complex mediated actin nucleation", "Artery development", "Artery morphogenesis", "Asparagine metabolic process", "Aspartate family amino acid biosynthetic process", "Aspartate family amino acid catabolic process", "Aspartate family amino acid metabolic process", "Aspartate metabolic process", "Aspartate transmembrane transport", "Associative learning", "Astral microtubule organization", "Astrocyte cell migration", "Astrocyte development", "Astrocyte differentiation", "Asymmetric cell division", "Asymmetric neuroblast division", "Atf6 mediated unfolded protein response", "Atp biosynthetic process", "Atp metabolic process", "Atp synthesis coupled electron transport", "Atp synthesis coupled proton transport", "Atp transport", "Atrial cardiac muscle cell membrane repolarization", "Atrial cardiac muscle cell to av node cell signaling", "Atrial septum development", "Atrial septum morphogenesis", "Atrioventricular canal development", "Attachment of gpi anchor to protein", "Attachment of mitotic spindle microtubules to kinetochore", "Attachment of spindle microtubules to kinetochore", "Auditory receptor cell development", "Auditory receptor cell morphogenesis", "Autonomic nervous system development", "Autophagic cell death", "Autophagosome lysosome fusion", "Autophagosome maturation", "Autophagosome membrane docking", "Autophagosome organization", "Autophagy of mitochondrion", "Autophagy of nucleus", "Av node cell to bundle of his cell communication", "Av node cell to bundle of his cell signaling", "Axial mesoderm development", "Axis elongation", "Axis specification", "Axo dendritic protein transport", "Axo dendritic transport", "Axon development", "Axon ensheathment in central nervous system", "Axon extension", "Axonal fasciculation", "Axonal transport", "Axonal transport of mitochondrion", "Axonemal dynein complex assembly", "Axoneme assembly", "Axonogenesis involved in innervation", "Azole transmembrane transport", "B cell activation", "B cell activation involved in immune response", "B cell apoptotic process", "B cell differentiation", "B cell homeostasis", "B cell lineage commitment", "B cell mediated immunity", "B cell proliferation", "B cell receptor signaling pathway", "Barbed end actin filament capping", "Base conversion or substitution editing", "Base excision repair", "Base excision repair ap site formation", "Base excision repair gap filling", "Basement membrane assembly", "Basement membrane organization", "Behavior", "Behavioral response to cocaine", "Behavioral response to ethanol", "Behavioral response to pain", "Benzene containing compound metabolic process", "Bergmann glial cell differentiation", "Bile acid and bile salt transport", "Bile acid biosynthetic process", "Bile acid metabolic process", "Bile acid secretion", "Bile acid signaling pathway", "Binding of sperm to zona pellucida", "Biological adhesion", "Biological phase", "Biological process involved in interaction with host", "Biological process involved in interaction with symbiont", "Biological process involved in interspecies interaction between organisms", "Biological process involved in intraspecies interaction between organisms", "Biological process involved in symbiotic interaction", "Biomineralization", "Blastocyst development", "Blastocyst formation", "Blastocyst growth", "Blastoderm segmentation", "Bleb assembly", "Blood vessel endothelial cell migration", "Blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Blood vessel maturation", "Blood vessel morphogenesis", "Blood vessel remodeling", "Body fluid secretion", "Body morphogenesis", "Bone cell development", "Bone development", "Bone growth", "Bone marrow development", "Bone maturation", "Bone mineralization", "Bone mineralization involved in bone maturation", "Bone morphogenesis", "Bone remodeling", "Bone resorption", "Box c d snornp assembly", "Bradykinin catabolic process", "Brain derived neurotrophic factor receptor signaling pathway", "Brain morphogenesis", "Brainstem development", "Branched chain amino acid biosynthetic process", "Branched chain amino acid catabolic process", "Branched chain amino acid metabolic process", "Branched chain amino acid transport", "Branching involved in blood vessel morphogenesis", "Branching involved in labyrinthine layer morphogenesis", "Branching involved in mammary gland duct morphogenesis", "Branching morphogenesis of a nerve", "Branching morphogenesis of an epithelial tube", "Brown fat cell differentiation", "Bundle of his cell to purkinje myocyte communication", "C 5 methylation of cytosine", "C terminal protein amino acid modification", "C terminal protein lipidation", "C21 steroid hormone biosynthetic process", "C21 steroid hormone metabolic process", "C4 dicarboxylate transport", "Calcineurin mediated signaling", "Calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules", "Calcium import into the mitochondrion", "Calcium ion export", "Calcium ion export across plasma membrane", "Calcium ion import", "Calcium ion import into sarcoplasmic reticulum", "Calcium ion regulated exocytosis", "Calcium ion regulated exocytosis of neurotransmitter", "Calcium ion transmembrane transport", "Calcium ion transmembrane transport via high voltage gated calcium channel", "Calcium ion transport", "Calcium ion transport into cytosol", "Calcium mediated signaling", "Calcium mediated signaling using intracellular calcium source", "Calmodulin dependent kinase signaling pathway", "Camera type eye development", "Camera type eye morphogenesis", "Camera type eye photoreceptor cell differentiation", "Camp mediated signaling", "Cannabinoid signaling pathway", "Canonical wnt signaling pathway", "Canonical wnt signaling pathway involved in heart development", "Canonical wnt signaling pathway involved in osteoblast differentiation", "Canonical wnt signaling pathway involved in regulation of cell proliferation", "Cap dependent translational initiation", "Carbohydrate biosynthetic process", "Carbohydrate catabolic process", "Carbohydrate derivative biosynthetic process", "Carbohydrate derivative catabolic process", "Carbohydrate derivative metabolic process", "Carbohydrate derivative transport", "Carbohydrate homeostasis", "Carbohydrate mediated signaling", "Carbohydrate metabolic process", "Carbohydrate phosphorylation", "Carbohydrate transmembrane transport", "Carbohydrate transport", "Carboxylic acid transport", "Cardiac atrium development", "Cardiac atrium morphogenesis", "Cardiac cell development", "Cardiac chamber development", "Cardiac chamber morphogenesis", "Cardiac conduction", "Cardiac conduction system development", "Cardiac epithelial to mesenchymal transition", "Cardiac muscle cell action potential", "Cardiac muscle cell action potential involved in contraction", "Cardiac muscle cell cardiac muscle cell adhesion", "Cardiac muscle cell contraction", "Cardiac muscle cell differentiation", "Cardiac muscle cell membrane repolarization", "Cardiac muscle cell proliferation", "Cardiac muscle contraction", "Cardiac muscle tissue development", "Cardiac muscle tissue morphogenesis", "Cardiac neural crest cell development involved in outflow tract morphogenesis", "Cardiac neural crest cell differentiation involved in heart development", "Cardiac neural crest cell migration involved in outflow tract morphogenesis", "Cardiac septum development", "Cardiac septum morphogenesis", "Cardiac ventricle development", "Cardiac ventricle morphogenesis", "Cardioblast differentiation", "Cardioblast proliferation", "Cardiocyte differentiation", "Cardiolipin acyl chain remodeling", "Cardiolipin biosynthetic process", "Cardiolipin metabolic process", "Carnitine metabolic process", "Carnitine transport", "Cartilage development", "Cartilage development involved in endochondral bone morphogenesis", "Catechol containing compound biosynthetic process", "Catechol containing compound catabolic process", "Catechol containing compound metabolic process", "Catecholamine uptake", "Catecholamine uptake involved in synaptic transmission", "Cation transmembrane transport", "Cation transport", "Caveola assembly", "Caveolin mediated endocytosis", "Cd4 positive alpha beta t cell activation", "Cd4 positive alpha beta t cell cytokine production", "Cd4 positive alpha beta t cell differentiation", "Cd4 positive alpha beta t cell proliferation", "Cd4 positive or cd8 positive alpha beta t cell lineage commitment", "Cd40 signaling pathway", "Cd8 positive alpha beta t cell activation", "Cd8 positive alpha beta t cell differentiation", "Cd8 positive alpha beta t cell proliferation", "Cdc42 protein signal transduction", "Cdp choline pathway", "Cdp diacylglycerol metabolic process", "Cell activation", "Cell activation involved in immune response", "Cell adhesion mediated by integrin", "Cell adhesion molecule production", "Cell aggregation", "Cell aging", "Cell cell adhesion", "Cell cell adhesion mediated by cadherin", "Cell cell adhesion mediated by integrin", "Cell cell adhesion via plasma membrane adhesion molecules", "Cell cell junction assembly", "Cell cell junction maintenance", "Cell cell junction organization", "Cell cell recognition", "Cell cell signaling", "Cell cell signaling by wnt", "Cell cell signaling involved in cardiac conduction", "Cell chemotaxis", "Cell communication by electrical coupling", "Cell communication by electrical coupling involved in cardiac conduction", "Cell communication involved in cardiac conduction", "Cell cycle", "Cell cycle checkpoint signaling", "Cell cycle dna replication", "Cell cycle dna replication initiation", "Cell cycle g1 s phase transition", "Cell cycle g2 m phase transition", "Cell cycle phase transition", "Cell cycle process", "Cell death in response to hydrogen peroxide", "Cell death in response to oxidative stress", "Cell differentiation in hindbrain", "Cell differentiation in spinal cord", "Cell differentiation involved in embryonic placenta development", "Cell differentiation involved in kidney development", "Cell differentiation involved in metanephros development", "Cell differentiation involved in phenotypic switching", "Cell division", "Cell fate commitment", "Cell fate commitment involved in formation of primary germ layer", "Cell fate determination", "Cell fate specification", "Cell growth", "Cell junction assembly", "Cell junction disassembly", "Cell junction maintenance", "Cell junction organization", "Cell killing", "Cell matrix adhesion", "Cell maturation", "Cell migration", "Cell migration in hindbrain", "Cell migration involved in gastrulation", "Cell migration involved in heart development", "Cell migration involved in sprouting angiogenesis", "Cell morphogenesis", "Cell morphogenesis involved in differentiation", "Cell morphogenesis involved in neuron differentiation", "Cell motility involved in cerebral cortex radial glia guided migration", "Cell part morphogenesis", "Cell projection assembly", "Cell projection organization", "Cell proliferation in forebrain", "Cell proliferation in hindbrain", "Cell proliferation involved in heart morphogenesis", "Cell proliferation involved in kidney development", "Cell proliferation involved in metanephros development", "Cell recognition", "Cell redox homeostasis", "Cell substrate adhesion", "Cell substrate junction organization", "Cell surface receptor signaling pathway involved in cell cell signaling", "Cell surface receptor signaling pathway involved in heart development", "Cell volume homeostasis", "Cellular aldehyde metabolic process", "Cellular amide metabolic process", "Cellular amino acid biosynthetic process", "Cellular amino acid catabolic process", "Cellular amino acid metabolic process", "Cellular anion homeostasis", "Cellular carbohydrate biosynthetic process", "Cellular carbohydrate catabolic process", "Cellular carbohydrate metabolic process", "Cellular component assembly involved in morphogenesis", "Cellular component disassembly", "Cellular component disassembly involved in execution phase of apoptosis", "Cellular component maintenance", "Cellular component morphogenesis", "Cellular copper ion homeostasis", "Cellular defense response", "Cellular detoxification of aldehyde", "Cellular extravasation", "Cellular glucan metabolic process", "Cellular glucose homeostasis", "Cellular homeostasis", "Cellular hormone metabolic process", "Cellular hyperosmotic response", "Cellular hyperosmotic salinity response", "Cellular hypotonic response", "Cellular ion homeostasis", "Cellular iron ion homeostasis", "Cellular ketone metabolic process", "Cellular lipid catabolic process", "Cellular lipid metabolic process", "Cellular macromolecule biosynthetic process", "Cellular macromolecule localization", "Cellular metabolic compound salvage", "Cellular modified amino acid biosynthetic process", "Cellular modified amino acid catabolic process", "Cellular modified amino acid metabolic process", "Cellular monovalent inorganic anion homeostasis", "Cellular monovalent inorganic cation homeostasis", "Cellular nitrogen compound catabolic process", "Cellular oxidant detoxification", "Cellular pigmentation", "Cellular polysaccharide catabolic process", "Cellular potassium ion homeostasis", "Cellular process involved in reproduction in multicellular organism", "Cellular protein catabolic process", "Cellular respiration", "Cellular response to abiotic stimulus", "Cellular response to acid chemical", "Cellular response to acidic ph", "Cellular response to alcohol", "Cellular response to aldehyde", "Cellular response to alkaloid", "Cellular response to amyloid beta", "Cellular response to antibiotic", "Cellular response to arsenic containing substance", "Cellular response to atp", "Cellular response to biotic stimulus", "Cellular response to brain derived neurotrophic factor stimulus", "Cellular response to cadmium ion", "Cellular response to caffeine", "Cellular response to calcium ion", "Cellular response to camp", "Cellular response to carbohydrate stimulus", "Cellular response to chemical stress", "Cellular response to cocaine", "Cellular response to cold", "Cellular response to copper ion", "Cellular response to corticosteroid stimulus", "Cellular response to dexamethasone stimulus", "Cellular response to dna damage stimulus", "Cellular response to dsrna", "Cellular response to electrical stimulus", "Cellular response to endogenous stimulus", "Cellular response to epinephrine stimulus", "Cellular response to estradiol stimulus", "Cellular response to estrogen stimulus", "Cellular response to ethanol", "Cellular response to ether", "Cellular response to exogenous dsrna", "Cellular response to external stimulus", "Cellular response to extracellular stimulus", "Cellular response to fatty acid", "Cellular response to fluid shear stress", "Cellular response to follicle stimulating hormone stimulus", "Cellular response to gamma radiation", "Cellular response to glucose starvation", "Cellular response to gonadotropin stimulus", "Cellular response to growth hormone stimulus", "Cellular response to heat", "Cellular response to histamine", "Cellular response to hormone stimulus", "Cellular response to hydrogen peroxide", "Cellular response to hyperoxia", "Cellular response to increased oxygen levels", "Cellular response to indole 3 methanol", "Cellular response to inorganic substance", "Cellular response to insulin like growth factor stimulus", "Cellular response to insulin stimulus", "Cellular response to interferon alpha", "Cellular response to interferon beta", "Cellular response to interferon gamma", "Cellular response to interleukin 1", "Cellular response to ionizing radiation", "Cellular response to iron ion", "Cellular response to ketone", "Cellular response to leptin stimulus", "Cellular response to leucine", "Cellular response to leucine starvation", "Cellular response to light intensity", "Cellular response to light stimulus", "Cellular response to lipid", "Cellular response to lipoprotein particle stimulus", "Cellular response to lithium ion", "Cellular response to low density lipoprotein particle stimulus", "Cellular response to magnesium ion", "Cellular response to manganese ion", "Cellular response to mechanical stimulus", "Cellular response to mineralocorticoid stimulus", "Cellular response to molecule of bacterial origin", "Cellular response to muramyl dipeptide", "Cellular response to nitrogen compound", "Cellular response to nitrogen starvation", "Cellular response to nitrosative stress", "Cellular response to nutrient", "Cellular response to organic cyclic compound", "Cellular response to osmotic stress", "Cellular response to oxidised low density lipoprotein particle stimulus", "Cellular response to oxygen containing compound", "Cellular response to oxygen glucose deprivation", "Cellular response to oxygen levels", "Cellular response to oxygen radical", "Cellular response to parathyroid hormone stimulus", "Cellular response to peptide", "Cellular response to peptide hormone stimulus", "Cellular response to peptidoglycan", "Cellular response to ph", "Cellular response to potassium ion", "Cellular response to progesterone stimulus", "Cellular response to prostaglandin e stimulus", "Cellular response to prostaglandin stimulus", "Cellular response to purine containing compound", "Cellular response to radiation", "Cellular response to reactive nitrogen species", "Cellular response to reactive oxygen species", "Cellular response to retinoic acid", "Cellular response to salt", "Cellular response to salt stress", "Cellular response to sodium arsenite", "Cellular response to starvation", "Cellular response to steroid hormone stimulus", "Cellular response to sterol depletion", "Cellular response to stress", "Cellular response to testosterone stimulus", "Cellular response to thyroid hormone stimulus", "Cellular response to topologically incorrect protein", "Cellular response to toxic substance", "Cellular response to unfolded protein", "Cellular response to uv", "Cellular response to uv a", "Cellular response to uv c", "Cellular response to vascular endothelial growth factor stimulus", "Cellular response to virus", "Cellular response to vitamin", "Cellular response to vitamin d", "Cellular response to water stimulus", "Cellular response to x ray", "Cellular response to xenobiotic stimulus", "Cellular response to zinc ion", "Cellular senescence", "Cellular sodium ion homeostasis", "Cellular sphingolipid homeostasis", "Cellular transition metal ion homeostasis", "Cellular triglyceride homeostasis", "Cellular trivalent inorganic anion homeostasis", "Cenp a containing chromatin organization", "Central nervous system development", "Central nervous system maturation", "Central nervous system myelin formation", "Central nervous system neuron axonogenesis", "Central nervous system neuron development", "Central nervous system neuron differentiation", "Central nervous system projection neuron axonogenesis", "Centriole assembly", "Centriole centriole cohesion", "Centriole elongation", "Centromere complex assembly", "Centromeric sister chromatid cohesion", "Centrosome duplication", "Centrosome separation", "Ceramide 1 phosphate transport", "Ceramide biosynthetic process", "Ceramide catabolic process", "Ceramide metabolic process", "Ceramide transport", "Cerebellar cortex development", "Cerebellar cortex formation", "Cerebellar cortex morphogenesis", "Cerebellar granular layer development", "Cerebellar granular layer formation", "Cerebellar granular layer morphogenesis", "Cerebellar purkinje cell layer development", "Cerebellar purkinje cell layer formation", "Cerebellar purkinje cell layer morphogenesis", "Cerebral cortex cell migration", "Cerebral cortex development", "Cerebral cortex neuron differentiation", "Cerebral cortex radially oriented cell migration", "Cerebral cortex regionalization", "Cerebrospinal fluid circulation", "Cgmp mediated signaling", "Changes to dna methylation involved in embryo development", "Chaperone cofactor dependent protein refolding", "Chaperone mediated autophagy", "Chaperone mediated protein complex assembly", "Chaperone mediated protein folding", "Chemical homeostasis", "Chemical homeostasis within a tissue", "Chemical synaptic transmission postsynaptic", "Chemokine c c motif ligand 5 production", "Chemokine c x c motif ligand 12 signaling pathway", "Chemokine c x c motif ligand 2 production", "Chemokine production", "Chemosensory behavior", "Chloride transmembrane transport", "Chloride transport", "Cholesterol catabolic process", "Cholesterol efflux", "Cholesterol storage", "Choline metabolic process", "Chondrocyte development", "Chondrocyte development involved in endochondral bone morphogenesis", "Chondrocyte differentiation", "Chondrocyte differentiation involved in endochondral bone morphogenesis", "Chondrocyte proliferation", "Chondroitin sulfate biosynthetic process", "Chondroitin sulfate proteoglycan biosynthetic process", "Chondroitin sulfate proteoglycan metabolic process", "Chorio allantoic fusion", "Chorion development", "Chromatin assembly or disassembly", "Chromatin disassembly", "Chromatin organization", "Chromatin remodeling", "Chromatin remodeling at centromere", "Chromosome attachment to the nuclear envelope", "Chromosome condensation", "Chromosome localization", "Chromosome localization to nuclear envelope involved in homologous chromosome segregation", "Chromosome movement towards spindle pole", "Chromosome organization", "Chromosome organization involved in meiotic cell cycle", "Chromosome segregation", "Chromosome separation", "Cilium movement", "Cilium or flagellum dependent cell motility", "Cilium organization", "Circadian regulation of gene expression", "Circadian rhythm", "Circulatory system development", "Circulatory system process", "Citrate metabolic process", "Citrulline biosynthetic process", "Citrulline metabolic process", "Clathrin coat assembly", "Clathrin dependent endocytosis", "Cleavage furrow formation", "Cleavage involved in rrna processing", "Cobalamin metabolic process", "Cobalamin transport", "Cobalt ion transport", "Cochlea development", "Cochlea morphogenesis", "Coenzyme a biosynthetic process", "Coenzyme a metabolic process", "Cognition", "Cohesin loading", "Collagen biosynthetic process", "Collagen catabolic process", "Collagen fibril organization", "Collagen metabolic process", "Collateral sprouting", "Collateral sprouting in absence of injury", "Collecting duct development", "Columnar cuboidal epithelial cell development", "Columnar cuboidal epithelial cell differentiation", "Columnar cuboidal epithelial cell maturation", "Common partner smad protein phosphorylation", "Complement activation", "Complement dependent cytotoxicity", "Connective tissue development", "Connective tissue replacement", "Constitutive heterochromatin assembly", "Constitutive secretory pathway", "Convergent extension", "Convergent extension involved in axis elongation", "Cop9 signalosome assembly", "Copi coated vesicle budding", "Copii coated vesicle budding", "Copii coated vesicle cargo loading", "Copper ion homeostasis", "Copper ion import", "Copper ion transmembrane transport", "Copper ion transport", "Copulation", "Coronary vasculature development", "Corpus callosum development", "Corpus callosum morphogenesis", "Cortical actin cytoskeleton organization", "Cortical cytoskeleton organization", "Corticosteroid hormone secretion", "Corticosteroid receptor signaling pathway", "Corticotropin secretion", "Cortisol secretion", "Cotranslational protein targeting to membrane", "Cranial ganglion development", "Cranial nerve development", "Cranial skeletal system development", "Crd mediated mrna stabilization", "Cristae formation", "Cyclic gmp amp transmembrane import across plasma membrane", "Cyclic nucleotide catabolic process", "Cyclic nucleotide mediated signaling", "Cyclic nucleotide metabolic process", "Cyclooxygenase pathway", "Cysteine metabolic process", "Cytochrome complex assembly", "Cytokine mediated signaling pathway", "Cytokine production", "Cytokine production involved in immune response", "Cytokine production involved in inflammatory response", "Cytokinesis", "Cytokinetic process", "Cytoplasm organization", "Cytoplasmic microtubule organization", "Cytoplasmic pattern recognition receptor signaling pathway", "Cytoplasmic pattern recognition receptor signaling pathway in response to virus", "Cytoplasmic sequestering of nf kappab", "Cytoplasmic sequestering of protein", "Cytoplasmic sequestering of transcription factor", "Cytoplasmic translation", "Cytoplasmic translational elongation", "Cytoplasmic translational initiation", "Cytoskeleton dependent cytokinesis", "Cytoskeleton dependent intracellular transport", "Cytoskeleton organization", "Cytosolic calcium ion transport", "Cytosolic transport", "D amino acid transport", "Damp metabolic process", "De novo amp biosynthetic process", "De novo protein folding", "De novo pyrimidine nucleobase biosynthetic process", "Deadenylation dependent decapping of nuclear transcribed mrna", "Decidualization", "Dedifferentiation", "Defense response", "Defense response to bacterium", "Defense response to fungus", "Defense response to gram negative bacterium", "Defense response to gram positive bacterium", "Defense response to other organism", "Defense response to symbiont", "Defense response to tumor cell", "Definitive erythrocyte differentiation", "Definitive hemopoiesis", "Demethylation", "Dendrite arborization", "Dendrite development", "Dendrite extension", "Dendrite morphogenesis", "Dendrite self avoidance", "Dendritic cell apoptotic process", "Dendritic cell chemotaxis", "Dendritic cell cytokine production", "Dendritic cell differentiation", "Dendritic cell migration", "Dendritic spine development", "Dendritic spine maintenance", "Dendritic spine morphogenesis", "Dendritic transport", "Dense core granule transport", "Dentate gyrus development", "Deoxyribonucleoside catabolic process", "Deoxyribonucleoside diphosphate metabolic process", "Deoxyribonucleoside metabolic process", "Deoxyribonucleoside monophosphate biosynthetic process", "Deoxyribonucleoside monophosphate catabolic process", "Deoxyribonucleoside monophosphate metabolic process", "Deoxyribonucleoside triphosphate biosynthetic process", "Deoxyribonucleoside triphosphate catabolic process", "Deoxyribonucleoside triphosphate metabolic process", "Deoxyribonucleotide biosynthetic process", "Deoxyribose phosphate catabolic process", "Deoxyribose phosphate metabolic process", "Dephosphorylation", "Dephosphorylation of rna polymerase ii c terminal domain", "Depyrimidination", "Dermatan sulfate biosynthetic process", "Dermatan sulfate metabolic process", "Dermatan sulfate proteoglycan metabolic process", "Desmosome organization", "Detection of abiotic stimulus", "Detection of biotic stimulus", "Detection of external biotic stimulus", "Detection of light stimulus", "Detection of mechanical stimulus", "Detection of molecule of bacterial origin", "Detection of muscle stretch", "Detection of other organism", "Detection of stimulus", "Detection of virus", "Detection of visible light", "Determination of adult lifespan", "Determination of dorsal ventral asymmetry", "Detoxification", "Detoxification of copper ion", "Detoxification of nitrogen compound", "Development of primary female sexual characteristics", "Development of primary sexual characteristics", "Development of secondary female sexual characteristics", "Development of secondary sexual characteristics", "Developmental cell growth", "Developmental growth", "Developmental growth involved in morphogenesis", "Developmental induction", "Developmental maturation", "Developmental pigmentation", "Developmental process involved in reproduction", "Diacylglycerol biosynthetic process", "Diacylglycerol metabolic process", "Diadenosine polyphosphate metabolic process", "Diapedesis", "Diaphragm development", "Dicarboxylic acid biosynthetic process", "Dicarboxylic acid catabolic process", "Dicarboxylic acid metabolic process", "Dicarboxylic acid transport", "Diencephalon development", "Digestion", "Digestive system development", "Digestive system process", "Digestive tract morphogenesis", "Diol biosynthetic process", "Diol metabolic process", "Disaccharide metabolic process", "Diterpenoid biosynthetic process", "Divalent inorganic cation homeostasis", "Dna biosynthetic process", "Dna catabolic process", "Dna catabolic process endonucleolytic", "Dna catabolic process exonucleolytic", "Dna conformation change", "Dna damage induced protein phosphorylation", "Dna damage response signal transduction by p53 class mediator", "Dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest", "Dna damage response signal transduction resulting in transcription", "Dna dealkylation", "Dna dealkylation involved in dna repair", "Dna deamination", "Dna dependent dna replication", "Dna dependent dna replication maintenance of fidelity", "Dna double strand break processing", "Dna endoreduplication", "Dna geometric change", "Dna integration", "Dna integrity checkpoint signaling", "Dna ligation", "Dna ligation involved in dna repair", "Dna metabolic process", "Dna methylation", "Dna methylation dependent heterochromatin assembly", "Dna methylation involved in gamete generation", "Dna methylation on cytosine", "Dna methylation or demethylation", "Dna modification", "Dna packaging", "Dna protection", "Dna recombination", "Dna repair", "Dna replication", "Dna replication checkpoint signaling", "Dna replication dependent chromatin organization", "Dna replication independent chromatin organization", "Dna replication initiation", "Dna replication synthesis of rna primer", "Dna strand elongation", "Dna strand elongation involved in dna replication", "Dna synthesis involved in dna repair", "Dna templated transcription elongation", "Dna templated transcription initiation", "Dna templated transcription termination", "Dna topological change", "Dna unwinding involved in dna replication", "Dolichol metabolic process", "Dopamine biosynthetic process", "Dopamine metabolic process", "Dopamine receptor signaling pathway", "Dopamine transport", "Dopaminergic neuron differentiation", "Dorsal root ganglion development", "Dorsal ventral axis specification", "Dorsal ventral neural tube patterning", "Dorsal ventral pattern formation", "Dosage compensation", "Double strand break repair", "Double strand break repair involved in meiotic recombination", "Double strand break repair via break induced replication", "Double strand break repair via classical nonhomologous end joining", "Double strand break repair via nonhomologous end joining", "Double strand break repair via synthesis dependent strand annealing", "Dsrna processing", "Dtmp metabolic process", "Dttp metabolic process", "Dump metabolic process", "Ear development", "Ear morphogenesis", "Early endosome to golgi transport", "Eating behavior", "Ectoderm development", "Ectodermal placode development", "Ectopic germ cell programmed cell death", "Egg activation", "Electron transport chain", "Embryo development", "Embryo development ending in birth or egg hatching", "Embryo implantation", "Embryonic appendage morphogenesis", "Embryonic axis specification", "Embryonic body morphogenesis", "Embryonic brain development", "Embryonic camera type eye development", "Embryonic cleavage", "Embryonic cranial skeleton morphogenesis", "Embryonic digestive tract development", "Embryonic digit morphogenesis", "Embryonic forelimb morphogenesis", "Embryonic heart tube development", "Embryonic heart tube morphogenesis", "Embryonic hemopoiesis", "Embryonic hindlimb morphogenesis", "Embryonic morphogenesis", "Embryonic neurocranium morphogenesis", "Embryonic organ development", "Embryonic organ morphogenesis", "Embryonic pattern specification", "Embryonic placenta development", "Embryonic placenta morphogenesis", "Embryonic process involved in female pregnancy", "Embryonic skeletal joint development", "Embryonic skeletal joint morphogenesis", "Embryonic skeletal system development", "Embryonic skeletal system morphogenesis", "Embryonic viscerocranium morphogenesis", "Endocannabinoid signaling pathway", "Endocardium development", "Endochondral bone morphogenesis", "Endocrine hormone secretion", "Endocrine pancreas development", "Endocrine process", "Endocrine system development", "Endocytic recycling", "Endocytosis", "Endoderm development", "Endoderm formation", "Endodermal cell differentiation", "Endodermal cell fate commitment", "Endomembrane system organization", "Endonucleolytic cleavage in 5 ets of tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage in its1 to separate ssu rrna from 5 8s rrna and lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage involved in rrna processing", "Endoplasmic reticulum calcium ion homeostasis", "Endoplasmic reticulum localization", "Endoplasmic reticulum mannose trimming", "Endoplasmic reticulum membrane organization", "Endoplasmic reticulum organization", "Endoplasmic reticulum plasma membrane tethering", "Endoplasmic reticulum to cytosol transport", "Endoplasmic reticulum to golgi vesicle mediated transport", "Endoplasmic reticulum tubular network organization", "Endoplasmic reticulum unfolded protein response", "Endosomal lumen acidification", "Endosomal transport", "Endosomal vesicle fusion", "Endosome organization", "Endosome to lysosome transport", "Endosome to lysosome transport via multivesicular body sorting pathway", "Endosome to plasma membrane protein transport", "Endosome transport via multivesicular body sorting pathway", "Endothelial cell activation", "Endothelial cell apoptotic process", "Endothelial cell chemotaxis", "Endothelial cell development", "Endothelial cell matrix adhesion", "Endothelial cell migration", "Endothelial cell morphogenesis", "Endothelial cell proliferation", "Endothelin receptor signaling pathway", "Endothelium development", "Energy derivation by oxidation of organic compounds", "Energy homeostasis", "Energy reserve metabolic process", "Engulfment of apoptotic cell", "Ensheathment of neurons", "Enteroendocrine cell differentiation", "Entrainment of circadian clock", "Entry into host", "Entry of bacterium into host cell", "Enzyme directed rrna pseudouridine synthesis", "Enzyme linked receptor protein signaling pathway", "Eosinophil activation", "Eosinophil chemotaxis", "Eosinophil mediated immunity", "Eosinophil migration", "Ephrin receptor signaling pathway", "Epiboly", "Epidermal cell differentiation", "Epidermis development", "Epidermis morphogenesis", "Epigenetic maintenance of chromatin in transcription competent conformation", "Epithelial cell apoptotic process", "Epithelial cell cell adhesion", "Epithelial cell development", "Epithelial cell differentiation", "Epithelial cell differentiation involved in kidney development", "Epithelial cell differentiation involved in prostate gland development", "Epithelial cell maturation", "Epithelial cell morphogenesis", "Epithelial cell proliferation", "Epithelial cell proliferation involved in lung morphogenesis", "Epithelial cell proliferation involved in prostate gland development", "Epithelial fluid transport", "Epithelial structure maintenance", "Epithelial to mesenchymal transition", "Epithelial tube branching involved in lung morphogenesis", "Epithelial tube formation", "Epithelial tube morphogenesis", "Epithelium development", "Epoxide metabolic process", "Er associated misfolded protein catabolic process", "Er nucleus signaling pathway", "Er overload response", "Erad pathway", "Erbb signaling pathway", "Erbb2 signaling pathway", "Erk1 and erk2 cascade", "Error free translesion synthesis", "Erythrocyte development", "Erythrocyte homeostasis", "Erythrocyte maturation", "Escrt complex disassembly", "Establishment of cell polarity", "Establishment of centrosome localization", "Establishment of endothelial barrier", "Establishment of endothelial intestinal barrier", "Establishment of epithelial cell apical basal polarity", "Establishment of epithelial cell polarity", "Establishment of golgi localization", "Establishment of lymphocyte polarity", "Establishment of meiotic spindle localization", "Establishment of mitochondrion localization", "Establishment of mitotic spindle localization", "Establishment of organelle localization", "Establishment of pigment granule localization", "Establishment of planar polarity involved in neural tube closure", "Establishment of planar polarity of embryonic epithelium", "Establishment of protein localization", "Establishment of protein localization to chromatin", "Establishment of protein localization to chromosome", "Establishment of protein localization to endoplasmic reticulum", "Establishment of protein localization to membrane", "Establishment of protein localization to mitochondrial membrane", "Establishment of protein localization to organelle", "Establishment of protein localization to plasma membrane", "Establishment of protein localization to telomere", "Establishment of protein localization to vacuole", "Establishment of rna localization", "Establishment of sister chromatid cohesion", "Establishment of spindle orientation", "Establishment of tissue polarity", "Establishment or maintenance of bipolar cell polarity", "Establishment or maintenance of cell polarity", "Establishment or maintenance of cytoskeleton polarity", "Establishment or maintenance of monopolar cell polarity", "Establishment or maintenance of transmembrane electrochemical gradient", "Estrogen biosynthetic process", "Estrogen metabolic process", "Estrous cycle", "Ethanol catabolic process", "Ethanol metabolic process", "Ethanol oxidation", "Ethanolamine containing compound metabolic process", "Ether biosynthetic process", "Ether metabolic process", "Excitatory synapse assembly", "Excretion", "Execution phase of apoptosis", "Exit from mitosis", "Exocrine pancreas development", "Exocrine system development", "Exocytic process", "Exocytosis", "Exonucleolytic catabolism of deadenylated mrna", "Exploration behavior", "Export across plasma membrane", "Export from cell", "External encapsulating structure organization", "Extracellular exosome assembly", "Extracellular matrix assembly", "Extracellular matrix disassembly", "Extracellular regulation of signal transduction", "Extracellular transport", "Extracellular vesicle biogenesis", "Extraembryonic membrane development", "Extrinsic apoptotic signaling pathway", "Extrinsic apoptotic signaling pathway via death domain receptors", "Eye morphogenesis", "Eye photoreceptor cell development", "Eye photoreceptor cell differentiation", "Eyelid development in camera type eye", "Face development", "Facultative heterochromatin assembly", "Farnesyl diphosphate metabolic process", "Fas signaling pathway", "Fat cell differentiation", "Fat cell proliferation", "Fat soluble vitamin metabolic process", "Fatty acid alpha oxidation", "Fatty acid beta oxidation", "Fatty acid beta oxidation using acyl coa dehydrogenase", "Fatty acid beta oxidation using acyl coa oxidase", "Fatty acid biosynthetic process", "Fatty acid catabolic process", "Fatty acid derivative biosynthetic process", "Fatty acid derivative catabolic process", "Fatty acid derivative metabolic process", "Fatty acid elongation", "Fatty acid homeostasis", "Fatty acid metabolic process", "Fatty acid omega oxidation", "Fatty acid transmembrane transport", "Fatty acid transport", "Fatty acyl coa biosynthetic process", "Fatty acyl coa catabolic process", "Fatty acyl coa metabolic process", "Fc epsilon receptor signaling pathway", "Fc gamma receptor signaling pathway", "Fc receptor mediated stimulatory signaling pathway", "Fc receptor signaling pathway", "Fear response", "Feeding behavior", "Female gamete generation", "Female genitalia development", "Female meiosis chromosome segregation", "Female meiosis i", "Female meiotic nuclear division", "Female sex differentiation", "Fermentation", "Fertilization", "Fibroblast activation", "Fibroblast apoptotic process", "Fibroblast growth factor production", "Fibroblast growth factor receptor signaling pathway", "Fibroblast migration", "Fibroblast proliferation", "Filopodium assembly", "Flavin containing compound metabolic process", "Flavonoid metabolic process", "Fluid transport", "Foam cell differentiation", "Focal adhesion assembly", "Folate import across plasma membrane", "Folate transmembrane transport", "Folic acid containing compound biosynthetic process", "Folic acid containing compound catabolic process", "Folic acid containing compound metabolic process", "Folic acid metabolic process", "Folic acid transport", "Forebrain cell migration", "Forebrain development", "Forebrain generation of neurons", "Forebrain morphogenesis", "Forebrain neuroblast division", "Forebrain neuron development", "Forebrain neuron differentiation", "Forebrain radial glial cell differentiation", "Forebrain regionalization", "Foregut morphogenesis", "Forelimb morphogenesis", "Formate metabolic process", "Formation of extrachromosomal circular dna", "Formation of primary germ layer", "Formation of translation preinitiation complex", "Free ubiquitin chain polymerization", "Fructose 1 6 bisphosphate metabolic process", "Fructose 6 phosphate metabolic process", "Fructose metabolic process", "Fucose metabolic process", "Fucosylation", "Fungiform papilla development", "Fungiform papilla morphogenesis", "G protein coupled acetylcholine receptor signaling pathway", "G protein coupled opioid receptor signaling pathway", "G protein coupled purinergic receptor signaling pathway", "G protein coupled receptor internalization", "G protein coupled receptor signaling pathway", "G protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger", "G protein coupled receptor signaling pathway involved in heart process", "G quadruplex dna unwinding", "G0 to g1 transition", "G1 to g0 transition", "Galactose catabolic process", "Galactose metabolic process", "Gamete generation", "Gamma aminobutyric acid metabolic process", "Gamma aminobutyric acid secretion", "Gamma aminobutyric acid signaling pathway", "Gamma aminobutyric acid transport", "Gamma delta t cell activation", "Ganglion development", "Ganglioside catabolic process", "Ganglioside metabolic process", "Gap junction assembly", "Gap junction mediated intercellular transport", "Gas homeostasis", "Gastrulation", "Gastrulation with mouth forming second", "Gdp mannose metabolic process", "Gdp metabolic process", "Gene silencing by rna", "Generation of precursor metabolites and energy", "Genitalia development", "Genitalia morphogenesis", "Genomic imprinting", "Germ cell development", "Germ cell migration", "Germ cell proliferation", "Germinal center b cell differentiation", "Germinal center formation", "Gland development", "Gland morphogenesis", "Glandular epithelial cell development", "Glandular epithelial cell differentiation", "Glial cell apoptotic process", "Glial cell development", "Glial cell differentiation", "Glial cell fate commitment", "Glial cell migration", "Glial cell proliferation", "Gliogenesis", "Glomerular epithelial cell development", "Glomerular epithelial cell differentiation", "Glomerular epithelium development", "Glomerular visceral epithelial cell migration", "Glomerulus development", "Glucan biosynthetic process", "Glucocorticoid biosynthetic process", "Glucocorticoid metabolic process", "Glucocorticoid secretion", "Glucosamine containing compound catabolic process", "Glucosamine containing compound metabolic process", "Glucose 6 phosphate metabolic process", "Glucose catabolic process", "Glucose import", "Glucose import in response to insulin stimulus", "Glucose metabolic process", "Glucosylceramide metabolic process", "Glutamate biosynthetic process", "Glutamate catabolic process", "Glutamate homeostasis", "Glutamate metabolic process", "Glutamate receptor signaling pathway", "Glutamate reuptake", "Glutamate secretion", "Glutamate secretion neurotransmission", "Glutamine family amino acid biosynthetic process", "Glutamine family amino acid catabolic process", "Glutamine family amino acid metabolic process", "Glutamine metabolic process", "Glutamine transport", "Glutathione catabolic process", "Glutathione metabolic process", "Glycerol 3 phosphate metabolic process", "Glycerol ether metabolic process", "Glycerolipid biosynthetic process", "Glycerolipid catabolic process", "Glycerolipid metabolic process", "Glycerophospholipid biosynthetic process", "Glycerophospholipid catabolic process", "Glycerophospholipid metabolic process", "Glycine biosynthetic process", "Glycine metabolic process", "Glycolipid biosynthetic process", "Glycolipid catabolic process", "Glycolipid transport", "Glycolytic fermentation", "Glycolytic process through fructose 6 phosphate", "Glycoprotein biosynthetic process", "Glycoprotein catabolic process", "Glycoprotein metabolic process", "Glycosaminoglycan catabolic process", "Glycoside catabolic process", "Glycoside metabolic process", "Glycosphingolipid biosynthetic process", "Glycosphingolipid metabolic process", "Glycosyl compound biosynthetic process", "Glycosyl compound catabolic process", "Glycosyl compound metabolic process", "Glycosylation", "Glycosylceramide biosynthetic process", "Glycosylceramide catabolic process", "Glycosylceramide metabolic process", "Glyoxylate metabolic process", "Gmp biosynthetic process", "Gmp metabolic process", "Gmp salvage", "Golgi disassembly", "Golgi localization", "Golgi organization", "Golgi ribbon formation", "Golgi to endosome transport", "Golgi to lysosome transport", "Golgi to plasma membrane protein transport", "Golgi to plasma membrane transport", "Golgi to vacuole transport", "Golgi vesicle budding", "Golgi vesicle transport", "Gpi anchor metabolic process", "Granulocyte activation", "Granulocyte chemotaxis", "Granulocyte differentiation", "Granulocyte migration", "Granzyme mediated programmed cell death signaling pathway", "Grooming behavior", "Growth", "Growth hormone receptor signaling pathway via jak stat", "Growth hormone secretion", "Growth plate cartilage chondrocyte differentiation", "Growth plate cartilage development", "Gtp biosynthetic process", "Gtp metabolic process", "Guanine metabolic process", "Guanine nucleotide transmembrane transport", "Guanine nucleotide transport", "Hair cell differentiation", "Hair cycle phase", "Hair follicle maturation", "Hair follicle placode formation", "Head development", "Head morphogenesis", "Heart development", "Heart formation", "Heart growth", "Heart morphogenesis", "Heart process", "Heart trabecula formation", "Heart trabecula morphogenesis", "Heart valve development", "Heart valve morphogenesis", "Heat acclimation", "Hematopoietic progenitor cell differentiation", "Hematopoietic stem cell differentiation", "Hematopoietic stem cell homeostasis", "Hematopoietic stem cell proliferation", "Heme transport", "Hemidesmosome assembly", "Hemoglobin biosynthetic process", "Hemoglobin metabolic process", "Hemostasis", "Heparan sulfate proteoglycan biosynthetic process", "Heparan sulfate proteoglycan metabolic process", "Hepatic stellate cell activation", "Hepaticobiliary system development", "Hepatocyte apoptotic process", "Hepatocyte differentiation", "Hepatocyte growth factor receptor signaling pathway", "Hepoxilin metabolic process", "Heterochromatin organization", "Heterophilic cell cell adhesion via plasma membrane cell adhesion molecules", "Heterotypic cell cell adhesion", "High density lipoprotein particle assembly", "High density lipoprotein particle clearance", "High density lipoprotein particle remodeling", "Hindbrain development", "Hindbrain maturation", "Hindbrain morphogenesis", "Hindbrain radial glia guided cell migration", "Hindlimb morphogenesis", "Hippo signaling", "Hippocampus development", "His purkinje system development", "Histamine production involved in inflammatory response", "Histamine secretion", "Histamine transport", "Histidine metabolic process", "Histone arginine methylation", "Histone deacetylation", "Histone dephosphorylation", "Histone deubiquitination", "Histone exchange", "Histone h2a acetylation", "Histone h2a k63 linked ubiquitination", "Histone h2a monoubiquitination", "Histone h2a phosphorylation", "Histone h2a ubiquitination", "Histone h2b ubiquitination", "Histone h3 acetylation", "Histone h3 deacetylation", "Histone h3 k14 acetylation", "Histone h3 k27 methylation", "Histone h3 k27 trimethylation", "Histone h3 k36 methylation", "Histone h3 k4 demethylation", "Histone h3 k4 dimethylation", "Histone h3 k4 methylation", "Histone h3 k4 monomethylation", "Histone h3 k4 trimethylation", "Histone h3 k9 acetylation", "Histone h3 k9 demethylation", "Histone h3 k9 dimethylation", "Histone h3 k9 methylation", "Histone h3 k9 modification", "Histone h3 k9 trimethylation", "Histone h4 acetylation", "Histone h4 deacetylation", "Histone h4 k12 acetylation", "Histone h4 k16 acetylation", "Histone h4 k20 methylation", "Histone h4 k20 trimethylation", "Histone h4 k5 acetylation", "Histone h4 r3 methylation", "Histone lysine demethylation", "Histone methylation", "Histone modification", "Histone monoubiquitination", "Histone mrna catabolic process", "Histone mrna metabolic process", "Histone phosphorylation", "Histone serine phosphorylation", "Histone threonine phosphorylation", "Histone ubiquitination", "Homeostasis of number of cells", "Homeostasis of number of cells within a tissue", "Homeostatic process", "Homocysteine metabolic process", "Homologous chromosome pairing at meiosis", "Homologous chromosome segregation", "Homologous recombination", "Homophilic cell adhesion via plasma membrane adhesion molecules", "Homotypic cell cell adhesion", "Hormone biosynthetic process", "Hormone catabolic process", "Hormone mediated signaling pathway", "Hormone metabolic process", "Hormone transport", "Humoral immune response", "Humoral immune response mediated by circulating immunoglobulin", "Hyaluronan biosynthetic process", "Hyaluronan metabolic process", "Hydrogen peroxide biosynthetic process", "Hydrogen peroxide catabolic process", "Hydrogen peroxide metabolic process", "Hydrogen sulfide biosynthetic process", "Hydrogen sulfide metabolic process", "Hyperosmotic response", "Hyperosmotic salinity response", "Hypothalamus cell differentiation", "Hypothalamus development", "Hypotonic response", "Hypoxia inducible factor 1alpha signaling pathway", "I kappab kinase nf kappab signaling", "I kappab phosphorylation", "Icosanoid biosynthetic process", "Icosanoid metabolic process", "Icosanoid transport", "Immune effector process", "Immune response", "Immune response regulating cell surface receptor signaling pathway", "Immune response regulating signaling pathway", "Immune response to tumor cell", "Immune system development", "Immunoglobulin production", "Immunoglobulin production involved in immunoglobulin mediated immune response", "Immunoglobulin v d j recombination", "Immunological memory process", "Immunological synapse formation", "Imp biosynthetic process", "Imp catabolic process", "Imp metabolic process", "Imp salvage", "Import across plasma membrane", "Import into cell", "Import into nucleus", "In utero embryonic development", "Inclusion body assembly", "Indolalkylamine metabolic process", "Indole containing compound biosynthetic process", "Indole containing compound metabolic process", "Inflammasome complex assembly", "Inflammatory cell apoptotic process", "Inflammatory response", "Inflammatory response to antigenic stimulus", "Inflammatory response to wounding", "Innate immune response", "Innate immune response activating signal transduction", "Innate immune response in mucosa", "Inner cell mass cell differentiation", "Inner cell mass cell proliferation", "Inner dynein arm assembly", "Inner ear auditory receptor cell differentiation", "Inner ear morphogenesis", "Inner ear receptor cell development", "Inner ear receptor cell stereocilium organization", "Inner mitochondrial membrane organization", "Innervation", "Inorganic anion transmembrane transport", "Inorganic anion transport", "Inorganic ion import across plasma membrane", "Inorganic ion transmembrane transport", "Inosine metabolic process", "Inositol lipid mediated signaling", "Inositol metabolic process", "Inositol phosphate catabolic process", "Inositol phosphate mediated signaling", "Inositol phosphate metabolic process", "Inositol trisphosphate metabolic process", "Insulin like growth factor receptor signaling pathway", "Insulin metabolic process", "Insulin processing", "Insulin receptor signaling pathway", "Insulin secretion", "Insulin secretion involved in cellular response to glucose stimulus", "Integrated stress response signaling", "Integrin activation", "Integrin mediated signaling pathway", "Intercellular transport", "Interferon alpha production", "Interferon beta production", "Interferon gamma mediated signaling pathway", "Interferon gamma production", "Interleukin 1 mediated signaling pathway", "Interleukin 1 production", "Interleukin 10 production", "Interleukin 12 production", "Interleukin 17 production", "Interleukin 18 mediated signaling pathway", "Interleukin 18 production", "Interleukin 2 production", "Interleukin 23 production", "Interleukin 27 mediated signaling pathway", "Interleukin 6 mediated signaling pathway", "Interleukin 6 production", "Interleukin 8 production", "Intermediate filament based process", "Intermediate filament bundle assembly", "Intermediate filament organization", "Intermembrane lipid transfer", "Interstrand cross link repair", "Intestinal absorption", "Intestinal epithelial cell development", "Intestinal epithelial cell differentiation", "Intestinal hexose absorption", "Intestinal lipid absorption", "Intra golgi vesicle mediated transport", "Intracellular distribution of mitochondria", "Intracellular estrogen receptor signaling pathway", "Intracellular lipid transport", "Intracellular mrna localization", "Intracellular protein transmembrane transport", "Intracellular protein transport", "Intracellular receptor signaling pathway", "Intracellular sterol transport", "Intracellular transport", "Intracellular transport of virus", "Intraciliary transport", "Intraciliary transport involved in cilium assembly", "Intrinsic apoptotic signaling pathway", "Intrinsic apoptotic signaling pathway by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to dna damage", "Intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress", "Intrinsic apoptotic signaling pathway in response to hydrogen peroxide", "Intrinsic apoptotic signaling pathway in response to hypoxia", "Intrinsic apoptotic signaling pathway in response to osmotic stress", "Intrinsic apoptotic signaling pathway in response to oxidative stress", "Ion homeostasis", "Ion transmembrane transport", "Ion transport", "Ire1 mediated unfolded protein response", "Ires dependent viral translational initiation", "Iron coordination entity transport", "Iron import into cell", "Iron ion homeostasis", "Iron ion import across plasma membrane", "Iron ion transmembrane transport", "Iron ion transport", "Iron sulfur cluster assembly", "Isocitrate metabolic process", "Isoleucine metabolic process", "Isopentenyl diphosphate biosynthetic process", "Isoprenoid biosynthetic process", "Isoprenoid metabolic process", "Isotype switching to iga isotypes", "Isotype switching to igg isotypes", "Jnk cascade", "Keratan sulfate metabolic process", "Keratinization", "Keratinocyte development", "Keratinocyte differentiation", "Keratinocyte migration", "Keratinocyte proliferation", "Ketone biosynthetic process", "Ketone body biosynthetic process", "Ketone body metabolic process", "Ketone catabolic process", "Kidney epithelium development", "Kidney mesenchyme development", "Kidney morphogenesis", "Killing by host of symbiont cells", "Killing of cells of another organism", "Kinetochore assembly", "Kinetochore organization", "Kynurenine metabolic process", "L alanine transport", "L alpha amino acid transmembrane transport", "L amino acid transport", "L ascorbic acid metabolic process", "L aspartate transmembrane transport", "L glutamate import across plasma membrane", "L glutamate transmembrane transport", "L kynurenine metabolic process", "L methionine salvage from methylthioadenosine", "L phenylalanine metabolic process", "L proline biosynthetic process", "L serine biosynthetic process", "L serine catabolic process", "L serine metabolic process", "L serine transport", "Labyrinthine layer blood vessel development", "Labyrinthine layer development", "Labyrinthine layer morphogenesis", "Lacrimal gland development", "Lactate metabolic process", "Lactate transmembrane transport", "Lactation", "Lamellipodium assembly", "Lamellipodium morphogenesis", "Lamellipodium organization", "Late endosome to golgi transport", "Late endosome to lysosome transport", "Late endosome to vacuole transport", "Late endosome to vacuole transport via multivesicular body sorting pathway", "Lateral ventricle development", "Layer formation in cerebral cortex", "Learning", "Lens development in camera type eye", "Lens fiber cell development", "Lens fiber cell differentiation", "Lens morphogenesis in camera type eye", "Leptin mediated signaling pathway", "Leucine catabolic process", "Leucine import across plasma membrane", "Leucine metabolic process", "Leucine transport", "Leukocyte adhesion to vascular endothelial cell", "Leukocyte aggregation", "Leukocyte apoptotic process", "Leukocyte cell cell adhesion", "Leukocyte chemotaxis", "Leukocyte degranulation", "Leukocyte differentiation", "Leukocyte homeostasis", "Leukocyte mediated cytotoxicity", "Leukocyte mediated immunity", "Leukocyte migration", "Leukocyte proliferation", "Leukocyte tethering or rolling", "Leukotriene b4 metabolic process", "Leukotriene biosynthetic process", "Leukotriene metabolic process", "Leukotriene transport", "Leydig cell differentiation", "Limb joint morphogenesis", "Limbic system development", "Linoleic acid metabolic process", "Lipid biosynthetic process", "Lipid catabolic process", "Lipid digestion", "Lipid droplet formation", "Lipid droplet organization", "Lipid export from cell", "Lipid glycosylation", "Lipid homeostasis", "Lipid import into cell", "Lipid localization", "Lipid metabolic process", "Lipid modification", "Lipid oxidation", "Lipid phosphorylation", "Lipid storage", "Lipid translocation", "Lipid transport across blood brain barrier", "Lipophagy", "Lipopolysaccharide mediated signaling pathway", "Lipoprotein biosynthetic process", "Lipoprotein catabolic process", "Lipoprotein localization", "Lipoprotein metabolic process", "Liposaccharide metabolic process", "Lipoxin metabolic process", "Liver morphogenesis", "Liver regeneration", "Localization within membrane", "Locomotion", "Locomotion involved in locomotory behavior", "Locomotor rhythm", "Locomotory behavior", "Locomotory exploration behavior", "Long chain fatty acid biosynthetic process", "Long chain fatty acid import across plasma membrane", "Long chain fatty acid metabolic process", "Long chain fatty acid transport", "Long chain fatty acyl coa biosynthetic process", "Long chain fatty acyl coa metabolic process", "Long term memory", "Long term synaptic depression", "Long term synaptic potentiation", "Low density lipoprotein particle clearance", "Low density lipoprotein receptor particle metabolic process", "Lung alveolus development", "Lung associated mesenchyme development", "Lung cell differentiation", "Lung epithelium development", "Lung morphogenesis", "Lung saccule development", "Lung secretory cell differentiation", "Luteinization", "Luteolysis", "Lymph vessel development", "Lymph vessel morphogenesis", "Lymphangiogenesis", "Lymphocyte activation", "Lymphocyte activation involved in immune response", "Lymphocyte aggregation", "Lymphocyte anergy", "Lymphocyte apoptotic process", "Lymphocyte chemotaxis", "Lymphocyte costimulation", "Lymphocyte homeostasis", "Lymphocyte mediated immunity", "Lymphocyte migration", "Lymphoid progenitor cell differentiation", "Lysine catabolic process", "Lysine metabolic process", "Lysosomal lumen acidification", "Lysosomal microautophagy", "Lysosomal protein catabolic process", "Lysosomal transport", "Lytic vacuole organization", "Macroautophagy", "Macromolecule catabolic process", "Macromolecule deacylation", "Macromolecule depalmitoylation", "Macrophage activation", "Macrophage apoptotic process", "Macrophage chemotaxis", "Macrophage cytokine production", "Macrophage differentiation", "Macrophage fusion", "Macrophage migration", "Macrophage proliferation", "Macropinocytosis", "Magnesium ion homeostasis", "Magnesium ion transport", "Maintenance of apical basal cell polarity", "Maintenance of blood brain barrier", "Maintenance of cell number", "Maintenance of cell polarity", "Maintenance of centrosome location", "Maintenance of dna methylation", "Maintenance of dna repeat elements", "Maintenance of gastrointestinal epithelium", "Maintenance of lens transparency", "Maintenance of location", "Maintenance of location in cell", "Maintenance of organelle location", "Maintenance of postsynaptic specialization structure", "Maintenance of presynaptic active zone structure", "Maintenance of protein localization in endoplasmic reticulum", "Maintenance of protein localization in organelle", "Maintenance of protein location", "Maintenance of protein location in cell", "Maintenance of protein location in mitochondrion", "Maintenance of protein location in nucleus", "Maintenance of sister chromatid cohesion", "Maintenance of synapse structure", "Malate metabolic process", "Male gamete generation", "Male genitalia development", "Male mating behavior", "Male meiosis i", "Male meiotic nuclear division", "Male sex determination", "Male sex differentiation", "Malonyl coa metabolic process", "Mammalian oogenesis stage", "Mammary gland alveolus development", "Mammary gland development", "Mammary gland duct morphogenesis", "Mammary gland epithelial cell differentiation", "Mammary gland epithelial cell proliferation", "Mammary gland epithelium development", "Mammary gland involution", "Mammary gland morphogenesis", "Manganese ion transmembrane transport", "Manganese ion transport", "Mannose metabolic process", "Mannosylation", "Mapk cascade", "Mast cell activation", "Mast cell activation involved in immune response", "Mast cell cytokine production", "Maternal placenta development", "Maternal process involved in female pregnancy", "Mating", "Mating behavior", "Maturation of 5 8s rrna", "Maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of lsu rrna", "Maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of ssu rrna", "Maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Mature b cell differentiation", "Mature ribosome assembly", "Mda 5 signaling pathway", "Mechanoreceptor differentiation", "Mechanosensory behavior", "Medium chain fatty acid biosynthetic process", "Medium chain fatty acid catabolic process", "Medium chain fatty acid metabolic process", "Medium chain fatty acyl coa metabolic process", "Megakaryocyte development", "Megakaryocyte differentiation", "Meiosis i cell cycle process", "Meiosis ii cell cycle process", "Meiotic cell cycle", "Meiotic cell cycle checkpoint signaling", "Meiotic cell cycle phase transition", "Meiotic cell cycle process", "Meiotic chromosome condensation", "Meiotic chromosome segregation", "Meiotic chromosome separation", "Meiotic cytokinesis", "Meiotic dna double strand break formation", "Meiotic sister chromatid cohesion centromeric", "Meiotic spindle assembly", "Meiotic spindle organization", "Melanocyte differentiation", "Membrane biogenesis", "Membrane depolarization", "Membrane depolarization during action potential", "Membrane depolarization during cardiac muscle cell action potential", "Membrane disassembly", "Membrane docking", "Membrane fission", "Membrane fusion", "Membrane hyperpolarization", "Membrane invagination", "Membrane lipid biosynthetic process", "Membrane lipid catabolic process", "Membrane lipid metabolic process", "Membrane organization", "Membrane protein ectodomain proteolysis", "Membrane protein intracellular domain proteolysis", "Membrane protein proteolysis", "Membrane raft assembly", "Membrane raft localization", "Membrane raft organization", "Membrane repolarization", "Membrane repolarization during action potential", "Membrane repolarization during atrial cardiac muscle cell action potential", "Membrane repolarization during cardiac muscle cell action potential", "Membrane to membrane docking", "Membranous septum morphogenesis", "Memory", "Mesangial cell development", "Mesangial cell differentiation", "Mesenchymal cell development", "Mesenchymal cell differentiation", "Mesenchymal cell differentiation involved in kidney development", "Mesenchymal cell proliferation", "Mesenchymal cell proliferation involved in lung development", "Mesenchymal stem cell differentiation", "Mesenchymal stem cell proliferation", "Mesenchymal to epithelial transition", "Mesenchymal to epithelial transition involved in metanephros morphogenesis", "Mesenchyme development", "Mesenchyme morphogenesis", "Mesoderm development", "Mesoderm morphogenesis", "Mesodermal cell differentiation", "Mesonephric duct development", "Mesonephric tubule formation", "Mesonephric tubule morphogenesis", "Mesonephros development", "Metal ion export", "Metal ion homeostasis", "Metal ion transport", "Metanephric collecting duct development", "Metanephric epithelium development", "Metanephric glomerulus development", "Metanephric glomerulus vasculature development", "Metanephric mesenchymal cell differentiation", "Metanephric mesenchyme development", "Metanephric nephron development", "Metanephric nephron morphogenesis", "Metanephric nephron tubule epithelial cell differentiation", "Metanephric part of ureteric bud development", "Metanephric renal vesicle morphogenesis", "Metanephric tubule development", "Metanephros development", "Metanephros morphogenesis", "Metaphase anaphase transition of cell cycle", "Metaphase plate congression", "Metencephalon development", "Methionine biosynthetic process", "Methionine metabolic process", "Methylation", "Methylglyoxal metabolic process", "Methylguanosine cap decapping", "Mhc class i biosynthetic process", "Mhc class ii biosynthetic process", "Microglia differentiation", "Microglial cell activation", "Microglial cell proliferation", "Microtubule anchoring", "Microtubule anchoring at centrosome", "Microtubule anchoring at microtubule organizing center", "Microtubule based movement", "Microtubule based process", "Microtubule based transport", "Microtubule bundle formation", "Microtubule cytoskeleton organization", "Microtubule cytoskeleton organization involved in mitosis", "Microtubule depolymerization", "Microtubule nucleation", "Microtubule organizing center localization", "Microtubule organizing center organization", "Microtubule polymerization", "Microtubule polymerization or depolymerization", "Microtubule severing", "Microvillus assembly", "Microvillus organization", "Midbody abscission", "Midbrain development", "Midbrain dopaminergic neuron differentiation", "Middle ear morphogenesis", "Midgut development", "Minus end directed organelle transport along microtubule", "Mirna catabolic process", "Mirna loading onto risc involved in gene silencing by mirna", "Mirna metabolic process", "Mismatch repair", "Mitochondrial acetyl coa biosynthetic process from pyruvate", "Mitochondrial adp transmembrane transport", "Mitochondrial atp synthesis coupled proton transport", "Mitochondrial calcium ion homeostasis", "Mitochondrial calcium ion transmembrane transport", "Mitochondrial cytochrome c oxidase assembly", "Mitochondrial depolarization", "Mitochondrial dna metabolic process", "Mitochondrial dna repair", "Mitochondrial dna replication", "Mitochondrial electron transport cytochrome c to oxygen", "Mitochondrial electron transport nadh to ubiquinone", "Mitochondrial electron transport ubiquinol to cytochrome c", "Mitochondrial fission", "Mitochondrial fragmentation involved in apoptotic process", "Mitochondrial fusion", "Mitochondrial gene expression", "Mitochondrial genome maintenance", "Mitochondrial membrane organization", "Mitochondrial outer membrane permeabilization", "Mitochondrial outer membrane permeabilization involved in programmed cell death", "Mitochondrial protein catabolic process", "Mitochondrial protein processing", "Mitochondrial proton transporting atp synthase complex assembly", "Mitochondrial respirasome assembly", "Mitochondrial respiratory chain complex assembly", "Mitochondrial ribosome assembly", "Mitochondrial rna 3 end processing", "Mitochondrial rna catabolic process", "Mitochondrial rna metabolic process", "Mitochondrial rna modification", "Mitochondrial rna processing", "Mitochondrial transcription", "Mitochondrial translation", "Mitochondrial translational elongation", "Mitochondrial transmembrane transport", "Mitochondrial transport", "Mitochondrial trna processing", "Mitochondrion distribution", "Mitochondrion endoplasmic reticulum membrane tethering", "Mitochondrion localization", "Mitochondrion morphogenesis", "Mitochondrion organization", "Mitophagy", "Mitotic cell cycle", "Mitotic cell cycle checkpoint signaling", "Mitotic cell cycle phase transition", "Mitotic cell cycle process", "Mitotic chromosome condensation", "Mitotic cytokinesis", "Mitotic cytokinetic process", "Mitotic dna integrity checkpoint signaling", "Mitotic dna replication", "Mitotic dna replication checkpoint signaling", "Mitotic g1 s transition checkpoint signaling", "Mitotic g2 dna damage checkpoint signaling", "Mitotic g2 m transition checkpoint", "Mitotic intra s dna damage checkpoint signaling", "Mitotic metaphase plate congression", "Mitotic nuclear division", "Mitotic nuclear membrane disassembly", "Mitotic nuclear membrane organization", "Mitotic recombination", "Mitotic sister chromatid cohesion", "Mitotic sister chromatid segregation", "Mitotic spindle assembly", "Mitotic spindle midzone assembly", "Mitotic spindle organization", "Modification dependent macromolecule catabolic process", "Modification of postsynaptic actin cytoskeleton", "Modification of postsynaptic structure", "Modification of synaptic structure", "Modified amino acid transport", "Modulation by host of symbiont catalytic activity", "Modulation by host of symbiont process", "Modulation by host of viral genome replication", "Modulation by host of viral process", "Modulation of age related behavioral decline", "Modulation of excitatory postsynaptic potential", "Molting cycle", "Monoacylglycerol catabolic process", "Monoacylglycerol metabolic process", "Monoamine transport", "Monocarboxylic acid biosynthetic process", "Monocarboxylic acid catabolic process", "Monocarboxylic acid metabolic process", "Monocarboxylic acid transport", "Monocyte chemotaxis", "Monocyte differentiation", "Monocyte extravasation", "Mononuclear cell differentiation", "Mononuclear cell migration", "Monosaccharide biosynthetic process", "Monosaccharide catabolic process", "Monosaccharide metabolic process", "Monoubiquitinated protein deubiquitination", "Monovalent inorganic anion homeostasis", "Monovalent inorganic cation homeostasis", "Morphogenesis of a branching structure", "Morphogenesis of a polarized epithelium", "Morphogenesis of an endothelium", "Morphogenesis of an epithelial bud", "Morphogenesis of an epithelial fold", "Morphogenesis of an epithelial sheet", "Morphogenesis of an epithelium", "Morphogenesis of embryonic epithelium", "Motor behavior", "Motor learning", "Motor neuron apoptotic process", "Motor neuron axon guidance", "Mrna 3 end processing", "Mrna 3 end processing by stem loop binding and cleavage", "Mrna 3 splice site recognition", "Mrna 5 splice site recognition", "Mrna alternative polyadenylation", "Mrna catabolic process", "Mrna cis splicing via spliceosome", "Mrna cleavage", "Mrna cleavage involved in mrna processing", "Mrna destabilization mediated gene silencing", "Mrna export from nucleus", "Mrna metabolic process", "Mrna methylation", "Mrna modification", "Mrna processing", "Mrna pseudouridine synthesis", "Mrna splice site selection", "Mrna transcription", "Mrna transport", "Mucopolysaccharide metabolic process", "Mucosa associated lymphoid tissue development", "Mucus secretion", "Multi multicellular organism process", "Multi organism reproductive process", "Multicellular organism aging", "Multicellular organism growth", "Multicellular organism reproduction", "Multicellular organismal homeostasis", "Multicellular organismal movement", "Multicellular organismal response to stress", "Multicellular organismal signaling", "Multinuclear osteoclast differentiation", "Multivesicular body organization", "Multivesicular body sorting pathway", "Muscle adaptation", "Muscle cell apoptotic process", "Muscle cell cellular homeostasis", "Muscle cell development", "Muscle cell differentiation", "Muscle cell migration", "Muscle cell proliferation", "Muscle contraction", "Muscle hypertrophy", "Muscle hypertrophy in response to stress", "Muscle organ development", "Muscle organ morphogenesis", "Muscle structure development", "Muscle system process", "Muscle tissue development", "Myd88 dependent toll like receptor signaling pathway", "Myelin assembly", "Myelin maintenance", "Myeloid cell activation involved in immune response", "Myeloid cell apoptotic process", "Myeloid cell development", "Myeloid cell differentiation", "Myeloid cell homeostasis", "Myeloid dendritic cell activation", "Myeloid dendritic cell cytokine production", "Myeloid leukocyte activation", "Myeloid leukocyte cytokine production", "Myeloid leukocyte differentiation", "Myeloid leukocyte mediated immunity", "Myeloid leukocyte migration", "Myeloid progenitor cell differentiation", "Myoblast differentiation", "Myoblast fusion", "Myoblast fusion involved in skeletal muscle regeneration", "Myoblast migration", "Myofibroblast differentiation", "Myosin filament organization", "Myotube cell development", "Myotube differentiation", "Myotube differentiation involved in skeletal muscle regeneration", "N acetylglucosamine metabolic process", "N acetylneuraminate catabolic process", "N acetylneuraminate metabolic process", "N acylethanolamine metabolic process", "N glycan processing", "N terminal peptidyl methionine acetylation", "N terminal protein amino acid acetylation", "N terminal protein amino acid modification", "N terminal protein lipidation", "Nad biosynthesis via nicotinamide riboside salvage pathway", "Nad metabolic process", "Nadh dehydrogenase complex assembly", "Nadh metabolic process", "Nadh oxidation", "Nadh regeneration", "Nadp metabolic process", "Nadph regeneration", "Natural killer cell activation", "Natural killer cell activation involved in immune response", "Natural killer cell degranulation", "Natural killer cell differentiation", "Natural killer cell mediated immunity", "Ncrna 3 end processing", "Ncrna catabolic process", "Ncrna export from nucleus", "Ncrna metabolic process", "Ncrna processing", "Ncrna transcription", "Necroptotic signaling pathway", "Necrotic cell death", "Negative chemotaxis", "Negative regulation by host of viral genome replication", "Negative regulation by host of viral process", "Negative regulation by host of viral transcription", "Negative regulation of actin filament bundle assembly", "Negative regulation of actin filament depolymerization", "Negative regulation of actin filament polymerization", "Negative regulation of actin nucleation", "Negative regulation of activated t cell proliferation", "Negative regulation of activin receptor signaling pathway", "Negative regulation of adaptive immune response", "Negative regulation of adenylate cyclase activating adrenergic receptor signaling pathway", "Negative regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Negative regulation of adenylate cyclase activity", "Negative regulation of alcohol biosynthetic process", "Negative regulation of alpha beta t cell activation", "Negative regulation of alpha beta t cell differentiation", "Negative regulation of alpha beta t cell proliferation", "Negative regulation of amine transport", "Negative regulation of amino acid transport", "Negative regulation of amyloid beta clearance", "Negative regulation of amyloid fibril formation", "Negative regulation of amyloid precursor protein biosynthetic process", "Negative regulation of amyloid precursor protein catabolic process", "Negative regulation of androgen receptor signaling pathway", "Negative regulation of anion transmembrane transport", "Negative regulation of anion transport", "Negative regulation of anoikis", "Negative regulation of antigen receptor mediated signaling pathway", "Negative regulation of apoptotic process involved in development", "Negative regulation of apoptotic signaling pathway", "Negative regulation of arp2 3 complex mediated actin nucleation", "Negative regulation of atp biosynthetic process", "Negative regulation of atp dependent activity", "Negative regulation of atp metabolic process", "Negative regulation of autophagosome assembly", "Negative regulation of autophagy", "Negative regulation of autophagy of mitochondrion", "Negative regulation of axon extension", "Negative regulation of axonogenesis", "Negative regulation of b cell activation", "Negative regulation of b cell apoptotic process", "Negative regulation of b cell differentiation", "Negative regulation of b cell mediated immunity", "Negative regulation of b cell proliferation", "Negative regulation of bicellular tight junction assembly", "Negative regulation of binding", "Negative regulation of biomineralization", "Negative regulation of biosynthetic process", "Negative regulation of blood circulation", "Negative regulation of blood pressure", "Negative regulation of blood vessel endothelial cell migration", "Negative regulation of bmp signaling pathway", "Negative regulation of bone mineralization", "Negative regulation of bone remodeling", "Negative regulation of calcineurin mediated signaling", "Negative regulation of calcium ion dependent exocytosis", "Negative regulation of calcium ion import", "Negative regulation of calcium ion transmembrane transport", "Negative regulation of calcium ion transport", "Negative regulation of calcium ion transport into cytosol", "Negative regulation of calcium mediated signaling", "Negative regulation of camp dependent protein kinase activity", "Negative regulation of canonical wnt signaling pathway", "Negative regulation of carbohydrate metabolic process", "Negative regulation of cardiac muscle adaptation", "Negative regulation of cardiac muscle contraction", "Negative regulation of cardiac muscle tissue growth", "Negative regulation of cartilage development", "Negative regulation of catabolic process", "Negative regulation of catalytic activity", "Negative regulation of cation channel activity", "Negative regulation of cd4 positive alpha beta t cell activation", "Negative regulation of cd4 positive alpha beta t cell differentiation", "Negative regulation of cell activation", "Negative regulation of cell adhesion", "Negative regulation of cell adhesion mediated by integrin", "Negative regulation of cell aging", "Negative regulation of cell cell adhesion", "Negative regulation of cell cell adhesion mediated by cadherin", "Negative regulation of cell cycle", "Negative regulation of cell cycle checkpoint", "Negative regulation of cell cycle g1 s phase transition", "Negative regulation of cell cycle g2 m phase transition", "Negative regulation of cell cycle phase transition", "Negative regulation of cell cycle process", "Negative regulation of cell death", "Negative regulation of cell development", "Negative regulation of cell differentiation", "Negative regulation of cell division", "Negative regulation of cell growth", "Negative regulation of cell growth involved in cardiac muscle cell development", "Negative regulation of cell junction assembly", "Negative regulation of cell killing", "Negative regulation of cell matrix adhesion", "Negative regulation of cell migration involved in sprouting angiogenesis", "Negative regulation of cell morphogenesis involved in differentiation", "Negative regulation of cell population proliferation", "Negative regulation of cell projection organization", "Negative regulation of cell proliferation involved in kidney development", "Negative regulation of cell size", "Negative regulation of cell substrate adhesion", "Negative regulation of cell substrate junction organization", "Negative regulation of cell volume", "Negative regulation of cellular amide metabolic process", "Negative regulation of cellular catabolic process", "Negative regulation of cellular component organization", "Negative regulation of cellular macromolecule biosynthetic process", "Negative regulation of cellular protein catabolic process", "Negative regulation of cellular respiration", "Negative regulation of cellular response to growth factor stimulus", "Negative regulation of cellular response to hypoxia", "Negative regulation of cellular response to insulin stimulus", "Negative regulation of cellular senescence", "Negative regulation of centriole replication", "Negative regulation of centrosome duplication", "Negative regulation of ceramide biosynthetic process", "Negative regulation of chemotaxis", "Negative regulation of cholesterol metabolic process", "Negative regulation of chondrocyte differentiation", "Negative regulation of chromatin binding", "Negative regulation of chromatin organization", "Negative regulation of chromosome organization", "Negative regulation of cilium assembly", "Negative regulation of circadian rhythm", "Negative regulation of cold induced thermogenesis", "Negative regulation of collateral sprouting", "Negative regulation of cyclic nucleotide phosphodiesterase activity", "Negative regulation of cyclin dependent protein serine threonine kinase activity", "Negative regulation of cysteine type endopeptidase activity", "Negative regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Negative regulation of cytokine production", "Negative regulation of cytokine production involved in immune response", "Negative regulation of cytokine production involved in inflammatory response", "Negative regulation of cytokinesis", "Negative regulation of cytoplasmic translation", "Negative regulation of cytoskeleton organization", "Negative regulation of cytosolic calcium ion concentration", "Negative regulation of defense response", "Negative regulation of defense response to bacterium", "Negative regulation of defense response to virus", "Negative regulation of delayed rectifier potassium channel activity", "Negative regulation of dendrite development", "Negative regulation of dendrite morphogenesis", "Negative regulation of dendritic spine development", "Negative regulation of dephosphorylation", "Negative regulation of developmental growth", "Negative regulation of developmental process", "Negative regulation of dna binding", "Negative regulation of dna binding transcription factor activity", "Negative regulation of dna biosynthetic process", "Negative regulation of dna damage checkpoint", "Negative regulation of dna damage response signal transduction by p53 class mediator", "Negative regulation of dna dependent dna replication", "Negative regulation of dna metabolic process", "Negative regulation of dna recombination", "Negative regulation of dna repair", "Negative regulation of dna replication", "Negative regulation of dna templated transcription elongation", "Negative regulation of dna templated transcription initiation", "Negative regulation of double strand break repair via homologous recombination", "Negative regulation of double strand break repair via nonhomologous end joining", "Negative regulation of endocytosis", "Negative regulation of endoplasmic reticulum calcium ion concentration", "Negative regulation of endoplasmic reticulum stress induced eif2 alpha phosphorylation", "Negative regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Negative regulation of endoplasmic reticulum unfolded protein response", "Negative regulation of endothelial cell proliferation", "Negative regulation of epidermal growth factor activated receptor activity", "Negative regulation of epidermis development", "Negative regulation of epithelial cell apoptotic process", "Negative regulation of epithelial cell differentiation", "Negative regulation of epithelial cell migration", "Negative regulation of epithelial cell proliferation", "Negative regulation of erad pathway", "Negative regulation of erbb signaling pathway", "Negative regulation of erk1 and erk2 cascade", "Negative regulation of erythrocyte differentiation", "Negative regulation of establishment of protein localization", "Negative regulation of establishment of protein localization to mitochondrion", "Negative regulation of excitatory postsynaptic potential", "Negative regulation of execution phase of apoptosis", "Negative regulation of exocytosis", "Negative regulation of extrinsic apoptotic signaling pathway", "Negative regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Negative regulation of fat cell differentiation", "Negative regulation of fatty acid beta oxidation", "Negative regulation of fatty acid biosynthetic process", "Negative regulation of fatty acid metabolic process", "Negative regulation of fatty acid oxidation", "Negative regulation of fatty acid transport", "Negative regulation of fibroblast apoptotic process", "Negative regulation of fibroblast migration", "Negative regulation of fibroblast proliferation", "Negative regulation of filopodium assembly", "Negative regulation of g protein coupled receptor signaling pathway", "Negative regulation of gene expression", "Negative regulation of gene expression epigenetic", "Negative regulation of glial cell differentiation", "Negative regulation of glial cell proliferation", "Negative regulation of gliogenesis", "Negative regulation of glucocorticoid metabolic process", "Negative regulation of gluconeogenesis", "Negative regulation of glucose import", "Negative regulation of glucose transmembrane transport", "Negative regulation of glycogen metabolic process", "Negative regulation of glycolytic process", "Negative regulation of glycoprotein metabolic process", "Negative regulation of golgi to plasma membrane protein transport", "Negative regulation of growth", "Negative regulation of gtpase activity", "Negative regulation of guanyl nucleotide exchange factor activity", "Negative regulation of heart rate", "Negative regulation of helicase activity", "Negative regulation of hematopoietic progenitor cell differentiation", "Negative regulation of hemopoiesis", "Negative regulation of hepatocyte apoptotic process", "Negative regulation of hippo signaling", "Negative regulation of histone acetylation", "Negative regulation of histone h3 k27 methylation", "Negative regulation of histone h3 k4 methylation", "Negative regulation of histone h3 k9 methylation", "Negative regulation of histone h3 k9 trimethylation", "Negative regulation of histone h4 acetylation", "Negative regulation of histone methylation", "Negative regulation of histone modification", "Negative regulation of histone phosphorylation", "Negative regulation of homotypic cell cell adhesion", "Negative regulation of hormone biosynthetic process", "Negative regulation of hormone metabolic process", "Negative regulation of hormone secretion", "Negative regulation of hydrogen peroxide mediated programmed cell death", "Negative regulation of hydrolase activity", "Negative regulation of hypoxia induced intrinsic apoptotic signaling pathway", "Negative regulation of i kappab kinase nf kappab signaling", "Negative regulation of immune effector process", "Negative regulation of immune response", "Negative regulation of immune system process", "Negative regulation of immunoglobulin production", "Negative regulation of inclusion body assembly", "Negative regulation of inflammatory response", "Negative regulation of inflammatory response to antigenic stimulus", "Negative regulation of innate immune response", "Negative regulation of interferon beta production", "Negative regulation of interferon gamma production", "Negative regulation of interleukin 1 mediated signaling pathway", "Negative regulation of interleukin 12 production", "Negative regulation of interleukin 2 production", "Negative regulation of interleukin 6 production", "Negative regulation of interleukin 8 production", "Negative regulation of intracellular estrogen receptor signaling pathway", "Negative regulation of intracellular protein transport", "Negative regulation of intracellular signal transduction", "Negative regulation of intracellular steroid hormone receptor signaling pathway", "Negative regulation of intracellular transport", "Negative regulation of intrinsic apoptotic signaling pathway", "Negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Negative regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Negative regulation of ion transmembrane transport", "Negative regulation of ion transmembrane transporter activity", "Negative regulation of ion transport", "Negative regulation of ire1 mediated unfolded protein response", "Negative regulation of isotype switching", "Negative regulation of jnk cascade", "Negative regulation of jun kinase activity", "Negative regulation of keratinocyte differentiation", "Negative regulation of keratinocyte proliferation", "Negative regulation of kidney development", "Negative regulation of kinase activity", "Negative regulation of leukocyte apoptotic process", "Negative regulation of leukocyte cell cell adhesion", "Negative regulation of leukocyte chemotaxis", "Negative regulation of leukocyte degranulation", "Negative regulation of leukocyte mediated immunity", "Negative regulation of leukocyte migration", "Negative regulation of leukocyte proliferation", "Negative regulation of lipase activity", "Negative regulation of lipid biosynthetic process", "Negative regulation of lipid catabolic process", "Negative regulation of lipid localization", "Negative regulation of lipid metabolic process", "Negative regulation of lipid storage", "Negative regulation of lipid transport", "Negative regulation of lipopolysaccharide mediated signaling pathway", "Negative regulation of lipoprotein particle clearance", "Negative regulation of locomotion", "Negative regulation of low density lipoprotein particle clearance", "Negative regulation of lyase activity", "Negative regulation of lymphocyte activation", "Negative regulation of lymphocyte apoptotic process", "Negative regulation of lymphocyte differentiation", "Negative regulation of lymphocyte mediated immunity", "Negative regulation of lymphocyte migration", "Negative regulation of macroautophagy", "Negative regulation of macrophage chemotaxis", "Negative regulation of macrophage migration", "Negative regulation of map kinase activity", "Negative regulation of mapk cascade", "Negative regulation of mast cell activation", "Negative regulation of mast cell activation involved in immune response", "Negative regulation of mast cell degranulation", "Negative regulation of megakaryocyte differentiation", "Negative regulation of meiotic cell cycle", "Negative regulation of meiotic nuclear division", "Negative regulation of membrane permeability", "Negative regulation of membrane potential", "Negative regulation of mesenchymal cell proliferation", "Negative regulation of metalloendopeptidase activity", "Negative regulation of metallopeptidase activity", "Negative regulation of metaphase anaphase transition of cell cycle", "Negative regulation of mhc class ii biosynthetic process", "Negative regulation of microtubule polymerization", "Negative regulation of microtubule polymerization or depolymerization", "Negative regulation of mirna transcription", "Negative regulation of mitochondrial fusion", "Negative regulation of mitochondrial membrane permeability", "Negative regulation of mitochondrial membrane permeability involved in apoptotic process", "Negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Negative regulation of mitochondrion organization", "Negative regulation of mitophagy", "Negative regulation of mitotic cell cycle", "Negative regulation of mitotic cell cycle phase transition", "Negative regulation of molecular function", "Negative regulation of monocyte differentiation", "Negative regulation of mononuclear cell migration", "Negative regulation of monooxygenase activity", "Negative regulation of mrna 3 end processing", "Negative regulation of mrna catabolic process", "Negative regulation of mrna metabolic process", "Negative regulation of mrna processing", "Negative regulation of mrna splicing via spliceosome", "Negative regulation of multicellular organismal process", "Negative regulation of muscle adaptation", "Negative regulation of muscle cell apoptotic process", "Negative regulation of muscle cell differentiation", "Negative regulation of muscle contraction", "Negative regulation of muscle hypertrophy", "Negative regulation of muscle organ development", "Negative regulation of muscle tissue development", "Negative regulation of myelination", "Negative regulation of myeloid cell apoptotic process", "Negative regulation of myeloid cell differentiation", "Negative regulation of myeloid leukocyte differentiation", "Negative regulation of myeloid leukocyte mediated immunity", "Negative regulation of myoblast differentiation", "Negative regulation of myosin light chain phosphatase activity", "Negative regulation of myotube differentiation", "Negative regulation of natural killer cell mediated immunity", "Negative regulation of necrotic cell death", "Negative regulation of nervous system development", "Negative regulation of nervous system process", "Negative regulation of neural precursor cell proliferation", "Negative regulation of neuroblast proliferation", "Negative regulation of neuron apoptotic process", "Negative regulation of neuron death", "Negative regulation of neuron differentiation", "Negative regulation of neuron migration", "Negative regulation of neuron projection development", "Negative regulation of neuron projection regeneration", "Negative regulation of neurotransmitter secretion", "Negative regulation of neurotransmitter transport", "Negative regulation of nf kappab transcription factor activity", "Negative regulation of nik nf kappab signaling", "Negative regulation of nitric oxide metabolic process", "Negative regulation of nitric oxide synthase activity", "Negative regulation of nlrp3 inflammasome complex assembly", "Negative regulation of notch signaling pathway", "Negative regulation of nuclear division", "Negative regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Negative regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Negative regulation of nuclease activity", "Negative regulation of nucleobase containing compound metabolic process", "Negative regulation of nucleocytoplasmic transport", "Negative regulation of nucleotide biosynthetic process", "Negative regulation of nucleotide metabolic process", "Negative regulation of oligodendrocyte differentiation", "Negative regulation of organ growth", "Negative regulation of organelle assembly", "Negative regulation of organelle organization", "Negative regulation of organic acid transport", "Negative regulation of ossification", "Negative regulation of osteoblast differentiation", "Negative regulation of osteoblast proliferation", "Negative regulation of osteoclast differentiation", "Negative regulation of oxidative phosphorylation", "Negative regulation of oxidative stress induced cell death", "Negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Negative regulation of oxidative stress induced neuron death", "Negative regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway", "Negative regulation of oxidoreductase activity", "Negative regulation of p38mapk cascade", "Negative regulation of peptidase activity", "Negative regulation of peptide secretion", "Negative regulation of peptidyl lysine acetylation", "Negative regulation of peptidyl serine phosphorylation", "Negative regulation of peptidyl threonine phosphorylation", "Negative regulation of peptidyl tyrosine phosphorylation", "Negative regulation of perk mediated unfolded protein response", "Negative regulation of phagocytosis", "Negative regulation of phosphatase activity", "Negative regulation of phosphatidylinositol 3 kinase signaling", "Negative regulation of phospholipase activity", "Negative regulation of phospholipid metabolic process", "Negative regulation of phosphoprotein phosphatase activity", "Negative regulation of phosphorus metabolic process", "Negative regulation of phosphorylation", "Negative regulation of plasma membrane bounded cell projection assembly", "Negative regulation of platelet derived growth factor receptor signaling pathway", "Negative regulation of posttranscriptional gene silencing", "Negative regulation of potassium ion transmembrane transport", "Negative regulation of potassium ion transport", "Negative regulation of production of mirnas involved in gene silencing by mirna", "Negative regulation of production of molecular mediator of immune response", "Negative regulation of programmed necrotic cell death", "Negative regulation of prostaglandin biosynthetic process", "Negative regulation of proteasomal protein catabolic process", "Negative regulation of proteasomal ubiquitin dependent protein catabolic process", "Negative regulation of protein acetylation", "Negative regulation of protein autophosphorylation", "Negative regulation of protein binding", "Negative regulation of protein catabolic process", "Negative regulation of protein containing complex assembly", "Negative regulation of protein containing complex disassembly", "Negative regulation of protein dephosphorylation", "Negative regulation of protein exit from endoplasmic reticulum", "Negative regulation of protein export from nucleus", "Negative regulation of protein import into nucleus", "Negative regulation of protein k63 linked ubiquitination", "Negative regulation of protein kinase activity by regulation of protein phosphorylation", "Negative regulation of protein kinase b signaling", "Negative regulation of protein localization", "Negative regulation of protein localization to cell periphery", "Negative regulation of protein localization to cell surface", "Negative regulation of protein localization to membrane", "Negative regulation of protein localization to nucleus", "Negative regulation of protein maturation", "Negative regulation of protein metabolic process", "Negative regulation of protein modification by small protein conjugation or removal", "Negative regulation of protein modification process", "Negative regulation of protein polymerization", "Negative regulation of protein polyubiquitination", "Negative regulation of protein secretion", "Negative regulation of protein serine threonine kinase activity", "Negative regulation of protein sumoylation", "Negative regulation of protein targeting to membrane", "Negative regulation of protein targeting to mitochondrion", "Negative regulation of protein tyrosine kinase activity", "Negative regulation of proteolysis", "Negative regulation of proteolysis involved in cellular protein catabolic process", "Negative regulation of reactive oxygen species biosynthetic process", "Negative regulation of reactive oxygen species metabolic process", "Negative regulation of receptor binding", "Negative regulation of receptor internalization", "Negative regulation of receptor mediated endocytosis", "Negative regulation of receptor signaling pathway via jak stat", "Negative regulation of receptor signaling pathway via stat", "Negative regulation of regulated secretory pathway", "Negative regulation of release of cytochrome c from mitochondria", "Negative regulation of reproductive process", "Negative regulation of respiratory burst", "Negative regulation of respiratory burst involved in inflammatory response", "Negative regulation of response to biotic stimulus", "Negative regulation of response to cytokine stimulus", "Negative regulation of response to dna damage stimulus", "Negative regulation of response to endoplasmic reticulum stress", "Negative regulation of response to external stimulus", "Negative regulation of response to food", "Negative regulation of response to oxidative stress", "Negative regulation of response to reactive oxygen species", "Negative regulation of response to stimulus", "Negative regulation of response to wounding", "Negative regulation of retinoic acid receptor signaling pathway", "Negative regulation of rho protein signal transduction", "Negative regulation of rig i signaling pathway", "Negative regulation of rna catabolic process", "Negative regulation of rna splicing", "Negative regulation of ruffle assembly", "Negative regulation of ryanodine sensitive calcium release channel activity", "Negative regulation of schwann cell proliferation", "Negative regulation of secondary metabolite biosynthetic process", "Negative regulation of secretion", "Negative regulation of sequestering of triglyceride", "Negative regulation of signal transduction by p53 class mediator", "Negative regulation of signal transduction in absence of ligand", "Negative regulation of signaling", "Negative regulation of signaling receptor activity", "Negative regulation of single stranded viral rna replication via double stranded dna intermediate", "Negative regulation of sister chromatid cohesion", "Negative regulation of small gtpase mediated signal transduction", "Negative regulation of small molecule metabolic process", "Negative regulation of smooth muscle cell apoptotic process", "Negative regulation of smooth muscle cell differentiation", "Negative regulation of smooth muscle cell migration", "Negative regulation of smooth muscle cell proliferation", "Negative regulation of smoothened signaling pathway", "Negative regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Negative regulation of sodium ion transmembrane transport", "Negative regulation of sodium ion transport", "Negative regulation of sphingolipid biosynthetic process", "Negative regulation of sprouting angiogenesis", "Negative regulation of stem cell differentiation", "Negative regulation of steroid metabolic process", "Negative regulation of stress activated protein kinase signaling cascade", "Negative regulation of striated muscle cell apoptotic process", "Negative regulation of striated muscle cell differentiation", "Negative regulation of striated muscle contraction", "Negative regulation of supramolecular fiber organization", "Negative regulation of synapse organization", "Negative regulation of synaptic transmission", "Negative regulation of synaptic transmission glutamatergic", "Negative regulation of synaptic vesicle exocytosis", "Negative regulation of systemic arterial blood pressure", "Negative regulation of t cell apoptotic process", "Negative regulation of t cell differentiation", "Negative regulation of t cell proliferation", "Negative regulation of t cell receptor signaling pathway", "Negative regulation of t helper cell differentiation", "Negative regulation of telomerase activity", "Negative regulation of telomere capping", "Negative regulation of telomere maintenance", "Negative regulation of telomere maintenance via telomerase", "Negative regulation of telomere maintenance via telomere lengthening", "Negative regulation of thymocyte apoptotic process", "Negative regulation of tissue remodeling", "Negative regulation of toll like receptor signaling pathway", "Negative regulation of tor signaling", "Negative regulation of transcription by competitive promoter binding", "Negative regulation of transcription by rna polymerase i", "Negative regulation of transcription by rna polymerase ii", "Negative regulation of transcription from rna polymerase ii promoter in response to stress", "Negative regulation of transcription initiation from rna polymerase ii promoter", "Negative regulation of transcription regulatory region dna binding", "Negative regulation of transferase activity", "Negative regulation of transforming growth factor beta production", "Negative regulation of transforming growth factor beta receptor signaling pathway", "Negative regulation of transforming growth factor beta1 production", "Negative regulation of translational elongation", "Negative regulation of translational initiation", "Negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Negative regulation of transmembrane transport", "Negative regulation of transport", "Negative regulation of transporter activity", "Negative regulation of trophoblast cell migration", "Negative regulation of tubulin deacetylation", "Negative regulation of tumor necrosis factor superfamily cytokine production", "Negative regulation of type 2 immune response", "Negative regulation of type b pancreatic cell apoptotic process", "Negative regulation of type i interferon mediated signaling pathway", "Negative regulation of type i interferon production", "Negative regulation of tyrosine phosphorylation of stat protein", "Negative regulation of ubiquitin dependent protein catabolic process", "Negative regulation of ubiquitin protein ligase activity", "Negative regulation of ubiquitin protein transferase activity", "Negative regulation of vascular associated smooth muscle cell apoptotic process", "Negative regulation of vascular associated smooth muscle cell differentiation", "Negative regulation of vascular associated smooth muscle cell migration", "Negative regulation of vascular associated smooth muscle cell proliferation", "Negative regulation of vascular endothelial growth factor production", "Negative regulation of vascular endothelial growth factor receptor signaling pathway", "Negative regulation of vascular permeability", "Negative regulation of vascular wound healing", "Negative regulation of vasculature development", "Negative regulation of viral entry into host cell", "Negative regulation of viral genome replication", "Negative regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Negative regulation of viral life cycle", "Negative regulation of viral process", "Negative regulation of viral transcription", "Negative regulation of vitamin metabolic process", "Negative regulation of voltage gated calcium channel activity", "Negative regulation of voltage gated potassium channel activity", "Negative regulation of wnt signaling pathway", "Negative regulation of wound healing", "Nephric duct development", "Nephric duct morphogenesis", "Nephron development", "Nephron epithelium development", "Nephron morphogenesis", "Nephron tubule epithelial cell differentiation", "Nephron tubule formation", "Nerve development", "Nerve growth factor signaling pathway", "Nervous system process", "Nervous system process involved in regulation of systemic arterial blood pressure", "Netrin activated signaling pathway", "Neural crest cell differentiation", "Neural crest cell migration", "Neural crest formation", "Neural nucleus development", "Neural plate development", "Neural precursor cell proliferation", "Neural retina development", "Neural tube development", "Neural tube formation", "Neural tube patterning", "Neuroblast division", "Neuroblast proliferation", "Neuroendocrine cell differentiation", "Neuroepithelial cell differentiation", "Neurofilament cytoskeleton organization", "Neurogenesis", "Neuroinflammatory response", "Neuromuscular junction development", "Neuromuscular process", "Neuromuscular process controlling balance", "Neuromuscular process controlling posture", "Neuromuscular synaptic transmission", "Neuron apoptotic process", "Neuron cellular homeostasis", "Neuron death", "Neuron death in response to hydrogen peroxide", "Neuron death in response to oxidative stress", "Neuron development", "Neuron differentiation", "Neuron fate commitment", "Neuron fate determination", "Neuron fate specification", "Neuron intrinsic apoptotic signaling pathway in response to oxidative stress", "Neuron maturation", "Neuron migration", "Neuron projection arborization", "Neuron projection extension", "Neuron projection guidance", "Neuron projection maintenance", "Neuron projection organization", "Neuron projection regeneration", "Neuron recognition", "Neuronal action potential", "Neuronal ion channel clustering", "Neuronal stem cell population maintenance", "Neuropeptide signaling pathway", "Neurotransmitter biosynthetic process", "Neurotransmitter catabolic process", "Neurotransmitter gated ion channel clustering", "Neurotransmitter metabolic process", "Neurotransmitter receptor internalization", "Neurotransmitter receptor localization to postsynaptic specialization membrane", "Neurotransmitter receptor transport", "Neurotransmitter receptor transport endosome to postsynaptic membrane", "Neurotransmitter receptor transport postsynaptic endosome to lysosome", "Neurotransmitter receptor transport to plasma membrane", "Neurotransmitter reuptake", "Neurotransmitter secretion", "Neurotransmitter transport", "Neurotransmitter uptake", "Neurotrophin production", "Neurotrophin signaling pathway", "Neurotrophin trk receptor signaling pathway", "Neutral amino acid transport", "Neutral lipid biosynthetic process", "Neutral lipid catabolic process", "Neutral lipid metabolic process", "Neutrophil activation involved in immune response", "Neutrophil apoptotic process", "Neutrophil chemotaxis", "Neutrophil clearance", "Neutrophil degranulation", "Neutrophil differentiation", "Neutrophil homeostasis", "Neutrophil mediated immunity", "Neutrophil migration", "Nik nf kappab signaling", "Nitric oxide synthase biosynthetic process", "Nitrogen compound transport", "Nitrogen utilization", "Nk t cell activation", "Nk t cell differentiation", "Nls bearing protein import into nucleus", "Non canonical wnt signaling pathway", "Non lytic viral release", "Non membrane bounded organelle assembly", "Non motile cilium assembly", "Nonribosomal peptide biosynthetic process", "Nose development", "Notch receptor processing", "Notch signaling pathway", "Nuclear body organization", "Nuclear chromosome segregation", "Nuclear envelope organization", "Nuclear export", "Nuclear membrane organization", "Nuclear membrane reassembly", "Nuclear migration", "Nuclear ncrna surveillance", "Nuclear pore complex assembly", "Nuclear pore organization", "Nuclear transcribed mrna catabolic process", "Nuclear transcribed mrna catabolic process deadenylation dependent decay", "Nuclear transcribed mrna catabolic process deadenylation independent decay", "Nuclear transcribed mrna catabolic process exonucleolytic", "Nuclear transcribed mrna catabolic process exonucleolytic 3 5", "Nuclear transcribed mrna catabolic process nonsense mediated decay", "Nuclear transcribed mrna poly a tail shortening", "Nuclear transport", "Nucleic acid phosphodiester bond hydrolysis", "Nucleobase biosynthetic process", "Nucleobase catabolic process", "Nucleobase containing compound transport", "Nucleobase containing small molecule biosynthetic process", "Nucleobase containing small molecule catabolic process", "Nucleobase containing small molecule interconversion", "Nucleobase containing small molecule metabolic process", "Nucleobase metabolic process", "Nucleobase transport", "Nucleolar chromatin organization", "Nucleolar large rrna transcription by rna polymerase i", "Nucleolus organization", "Nucleoside bisphosphate biosynthetic process", "Nucleoside bisphosphate catabolic process", "Nucleoside bisphosphate metabolic process", "Nucleoside catabolic process", "Nucleoside diphosphate biosynthetic process", "Nucleoside diphosphate catabolic process", "Nucleoside diphosphate metabolic process", "Nucleoside metabolic process", "Nucleoside monophosphate biosynthetic process", "Nucleoside monophosphate catabolic process", "Nucleoside monophosphate metabolic process", "Nucleoside monophosphate phosphorylation", "Nucleoside phosphate biosynthetic process", "Nucleoside phosphate catabolic process", "Nucleoside salvage", "Nucleoside transmembrane transport", "Nucleoside transport", "Nucleoside triphosphate biosynthetic process", "Nucleoside triphosphate catabolic process", "Nucleoside triphosphate metabolic process", "Nucleosome assembly", "Nucleosome mobilization", "Nucleosome organization", "Nucleosome positioning", "Nucleotide binding domain leucine rich repeat containing receptor signaling pathway", "Nucleotide binding oligomerization domain containing 2 signaling pathway", "Nucleotide excision repair", "Nucleotide excision repair dna gap filling", "Nucleotide excision repair dna incision", "Nucleotide phosphorylation", "Nucleotide salvage", "Nucleotide sugar biosynthetic process", "Nucleotide sugar metabolic process", "Nucleotide sugar transmembrane transport", "Nucleotide transmembrane transport", "Nucleotide transport", "Nucleus localization", "Nucleus organization", "O glycan processing", "Odontoblast differentiation", "Odontogenesis", "Odontogenesis of dentin containing tooth", "Olefinic compound biosynthetic process", "Olefinic compound metabolic process", "Olfactory behavior", "Olfactory lobe development", "Oligodendrocyte development", "Oligodendrocyte differentiation", "Oligodendrocyte progenitor proliferation", "Oligopeptide transport", "Oligosaccharide catabolic process", "Oligosaccharide lipid intermediate biosynthetic process", "Oligosaccharide metabolic process", "One carbon metabolic process", "Oocyte construction", "Oocyte differentiation", "Oocyte maturation", "Oogenesis", "Optic nerve development", "Organ growth", "Organ induction", "Organ or tissue specific immune response", "Organelle assembly", "Organelle disassembly", "Organelle fission", "Organelle fusion", "Organelle inheritance", "Organelle localization", "Organelle membrane fusion", "Organelle transport along microtubule", "Organic acid biosynthetic process", "Organic acid catabolic process", "Organic acid metabolic process", "Organic acid transmembrane transport", "Organic acid transport", "Organic anion transport", "Organic cation transport", "Organic cyclic compound catabolic process", "Organic hydroxy compound biosynthetic process", "Organic hydroxy compound catabolic process", "Organic hydroxy compound metabolic process", "Organic hydroxy compound transport", "Organism emergence from protective structure", "Organonitrogen compound biosynthetic process", "Organonitrogen compound catabolic process", "Organophosphate biosynthetic process", "Organophosphate catabolic process", "Organophosphate ester transport", "Organophosphate metabolic process", "Ornithine metabolic process", "Ornithine transport", "Ossification", "Osteoblast differentiation", "Osteoblast proliferation", "Osteoclast development", "Osteoclast differentiation", "Osteoclast fusion", "Otolith development", "Outer dynein arm assembly", "Outer ear morphogenesis", "Outer mitochondrial membrane organization", "Outflow tract morphogenesis", "Ovarian follicle development", "Oviduct development", "Ovulation", "Ovulation cycle", "Ovulation cycle process", "Ovulation from ovarian follicle", "Oxaloacetate metabolic process", "Oxaloacetate transport", "Oxidative demethylation", "Oxidative dna demethylation", "Oxidative phosphorylation", "Oxidative rna demethylation", "Oxygen homeostasis", "P body assembly", "P38mapk cascade", "Pallium development", "Pancreas development", "Pancreatic juice secretion", "Pantothenate metabolic process", "Parallel actin filament bundle assembly", "Paranodal junction assembly", "Parathyroid gland development", "Paraxial mesoderm development", "Paraxial mesoderm formation", "Paraxial mesoderm morphogenesis", "Parkin mediated stimulation of mitophagy in response to mitochondrial depolarization", "Pathway restricted smad protein phosphorylation", "Pattern recognition receptor signaling pathway", "Pattern specification involved in kidney development", "Pattern specification process", "Penetration of zona pellucida", "Penile erection", "Pentose catabolic process", "Pentose metabolic process", "Pentose phosphate shunt", "Pentose phosphate shunt non oxidative branch", "Peptide antigen assembly with mhc protein complex", "Peptide biosynthetic process", "Peptide catabolic process", "Peptide cross linking", "Peptide metabolic process", "Peptide transport", "Peptidyl amino acid modification", "Peptidyl arginine methylation", "Peptidyl arginine methylation to asymmetrical dimethyl arginine", "Peptidyl arginine modification", "Peptidyl arginine n methylation", "Peptidyl asparagine modification", "Peptidyl cysteine modification", "Peptidyl diphthamide biosynthetic process from peptidyl histidine", "Peptidyl glutamic acid modification", "Peptidyl glutamine methylation", "Peptidyl histidine modification", "Peptidyl lysine acetylation", "Peptidyl lysine deacetylation", "Peptidyl lysine dimethylation", "Peptidyl lysine hydroxylation", "Peptidyl lysine methylation", "Peptidyl lysine modification", "Peptidyl lysine monomethylation", "Peptidyl lysine trimethylation", "Peptidyl methionine modification", "Peptidyl proline hydroxylation", "Peptidyl proline hydroxylation to 4 hydroxy l proline", "Peptidyl proline modification", "Peptidyl serine autophosphorylation", "Peptidyl serine dephosphorylation", "Peptidyl serine modification", "Peptidyl threonine dephosphorylation", "Peptidyl threonine modification", "Peptidyl tyrosine autophosphorylation", "Peptidyl tyrosine dephosphorylation", "Peptidyl tyrosine dephosphorylation involved in inactivation of protein kinase activity", "Peptidyl tyrosine modification", "Pericyte cell differentiation", "Peripheral nervous system axon regeneration", "Peripheral nervous system development", "Peripheral nervous system myelin maintenance", "Perk mediated unfolded protein response", "Peroxisomal transport", "Peroxisome fission", "Peroxisome organization", "Peroxisome proliferator activated receptor signaling pathway", "Ph reduction", "Phagocytosis", "Phagocytosis recognition", "Phagolysosome assembly", "Phagosome acidification", "Phagosome lysosome fusion", "Phagosome maturation", "Pharyngeal system development", "Phenol containing compound biosynthetic process", "Phenol containing compound catabolic process", "Phenol containing compound metabolic process", "Phenotypic switching", "Phosphagen metabolic process", "Phosphate ion transmembrane transport", "Phosphate ion transport", "Phosphatidic acid metabolic process", "Phosphatidylcholine acyl chain remodeling", "Phosphatidylcholine biosynthetic process", "Phosphatidylcholine catabolic process", "Phosphatidylcholine metabolic process", "Phosphatidylethanolamine biosynthetic process", "Phosphatidylethanolamine metabolic process", "Phosphatidylglycerol acyl chain remodeling", "Phosphatidylglycerol biosynthetic process", "Phosphatidylglycerol metabolic process", "Phosphatidylinositol 3 kinase signaling", "Phosphatidylinositol 3 phosphate biosynthetic process", "Phosphatidylinositol acyl chain remodeling", "Phosphatidylinositol biosynthetic process", "Phosphatidylinositol dephosphorylation", "Phosphatidylinositol metabolic process", "Phosphatidylinositol phosphate biosynthetic process", "Phosphatidylserine acyl chain remodeling", "Phosphatidylserine metabolic process", "Phospholipase c activating dopamine receptor signaling pathway", "Phospholipase c activating g protein coupled receptor signaling pathway", "Phospholipid biosynthetic process", "Phospholipid catabolic process", "Phospholipid dephosphorylation", "Phospholipid metabolic process", "Phospholipid transport", "Phosphorylation", "Phosphorylation of rna polymerase ii c terminal domain", "Photoperiodism", "Photoreceptor cell development", "Photoreceptor cell differentiation", "Photoreceptor cell maintenance", "Photoreceptor cell outer segment organization", "Phototransduction", "Phototransduction visible light", "Physiological cardiac muscle hypertrophy", "Pigment accumulation", "Pigment biosynthetic process", "Pigment cell differentiation", "Pigment granule localization", "Pigment granule maturation", "Pigment granule organization", "Pigment metabolic process", "Pigmentation", "Pinocytosis", "Pirna metabolic process", "Pituitary gland development", "Placenta blood vessel development", "Placenta development", "Planar cell polarity pathway involved in neural tube closure", "Plasma lipoprotein particle clearance", "Plasma membrane fusion", "Plasma membrane organization", "Plasma membrane raft assembly", "Plasma membrane raft organization", "Plasma membrane repair", "Plasma membrane to endosome transport", "Plasma membrane tubulation", "Plasminogen activation", "Platelet activating factor metabolic process", "Platelet activation", "Platelet aggregation", "Platelet degranulation", "Platelet derived growth factor receptor beta signaling pathway", "Platelet derived growth factor receptor signaling pathway", "Platelet morphogenesis", "Plus end directed organelle transport along microtubule", "Pml body organization", "Podosome assembly", "Pointed end actin filament capping", "Polarized epithelial cell differentiation", "Poly a plus mrna export from nucleus", "Poly n acetyllactosamine metabolic process", "Polyadenylation dependent rna catabolic process", "Polyadenylation dependent snorna 3 end processing", "Polyamine biosynthetic process", "Polyamine metabolic process", "Polyketide metabolic process", "Polyol biosynthetic process", "Polyol catabolic process", "Polyol metabolic process", "Polyprenol metabolic process", "Polysaccharide biosynthetic process", "Polysaccharide catabolic process", "Polysaccharide metabolic process", "Pons development", "Pore complex assembly", "Porphyrin containing compound metabolic process", "Positive chemotaxis", "Positive regulation by host of viral genome replication", "Positive regulation by host of viral process", "Positive regulation by host of viral transcription", "Positive regulation by symbiont of entry into host", "Positive regulation of 3 utr mediated mrna stabilization", "Positive regulation of actin cytoskeleton reorganization", "Positive regulation of actin filament bundle assembly", "Positive regulation of actin filament depolymerization", "Positive regulation of actin filament polymerization", "Positive regulation of actin nucleation", "Positive regulation of action potential", "Positive regulation of activated t cell proliferation", "Positive regulation of activin receptor signaling pathway", "Positive regulation of acute inflammatory response", "Positive regulation of acute inflammatory response to antigenic stimulus", "Positive regulation of adaptive immune response", "Positive regulation of adipose tissue development", "Positive regulation of alcohol biosynthetic process", "Positive regulation of alpha beta t cell activation", "Positive regulation of alpha beta t cell differentiation", "Positive regulation of alpha beta t cell proliferation", "Positive regulation of amine transport", "Positive regulation of amino acid transport", "Positive regulation of amyloid beta clearance", "Positive regulation of amyloid beta formation", "Positive regulation of amyloid precursor protein biosynthetic process", "Positive regulation of amyloid precursor protein catabolic process", "Positive regulation of animal organ morphogenesis", "Positive regulation of anion transmembrane transport", "Positive regulation of anion transport", "Positive regulation of anoikis", "Positive regulation of antigen receptor mediated signaling pathway", "Positive regulation of apoptotic dna fragmentation", "Positive regulation of apoptotic process involved in development", "Positive regulation of apoptotic process involved in morphogenesis", "Positive regulation of apoptotic signaling pathway", "Positive regulation of arp2 3 complex mediated actin nucleation", "Positive regulation of aspartic type peptidase activity", "Positive regulation of astrocyte differentiation", "Positive regulation of atp biosynthetic process", "Positive regulation of atp dependent activity", "Positive regulation of atp metabolic process", "Positive regulation of atpase coupled calcium transmembrane transporter activity", "Positive regulation of attachment of spindle microtubules to kinetochore", "Positive regulation of autophagy", "Positive regulation of autophagy of mitochondrion", "Positive regulation of axon extension", "Positive regulation of axonogenesis", "Positive regulation of b cell activation", "Positive regulation of b cell mediated immunity", "Positive regulation of b cell proliferation", "Positive regulation of b cell receptor signaling pathway", "Positive regulation of basement membrane assembly involved in embryonic body morphogenesis", "Positive regulation of behavior", "Positive regulation of binding", "Positive regulation of biomineralization", "Positive regulation of blood brain barrier permeability", "Positive regulation of blood circulation", "Positive regulation of blood pressure", "Positive regulation of blood vessel endothelial cell migration", "Positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Positive regulation of bmp signaling pathway", "Positive regulation of bone mineralization", "Positive regulation of bone resorption", "Positive regulation of brown fat cell differentiation", "Positive regulation of calcineurin mediated signaling", "Positive regulation of calcium ion import", "Positive regulation of calcium ion transmembrane transport", "Positive regulation of calcium ion transmembrane transporter activity", "Positive regulation of calcium ion transport", "Positive regulation of calcium ion transport into cytosol", "Positive regulation of calcium mediated signaling", "Positive regulation of camp dependent protein kinase activity", "Positive regulation of camp mediated signaling", "Positive regulation of canonical wnt signaling pathway", "Positive regulation of carbohydrate metabolic process", "Positive regulation of cardiac muscle adaptation", "Positive regulation of cardiac muscle cell proliferation", "Positive regulation of cardioblast differentiation", "Positive regulation of cardiocyte differentiation", "Positive regulation of cartilage development", "Positive regulation of catabolic process", "Positive regulation of catalytic activity", "Positive regulation of catecholamine metabolic process", "Positive regulation of cation channel activity", "Positive regulation of cd4 positive alpha beta t cell activation", "Positive regulation of cd4 positive alpha beta t cell differentiation", "Positive regulation of cd4 positive alpha beta t cell proliferation", "Positive regulation of cd8 positive alpha beta t cell activation", "Positive regulation of cd8 positive alpha beta t cell differentiation", "Positive regulation of cell activation", "Positive regulation of cell adhesion", "Positive regulation of cell adhesion molecule production", "Positive regulation of cell aging", "Positive regulation of cell cell adhesion", "Positive regulation of cell cell adhesion mediated by cadherin", "Positive regulation of cell cycle", "Positive regulation of cell cycle checkpoint", "Positive regulation of cell cycle g1 s phase transition", "Positive regulation of cell cycle g2 m phase transition", "Positive regulation of cell cycle phase transition", "Positive regulation of cell cycle process", "Positive regulation of cell death", "Positive regulation of cell development", "Positive regulation of cell differentiation", "Positive regulation of cell division", "Positive regulation of cell growth", "Positive regulation of cell growth involved in cardiac muscle cell development", "Positive regulation of cell junction assembly", "Positive regulation of cell killing", "Positive regulation of cell matrix adhesion", "Positive regulation of cell maturation", "Positive regulation of cell migration by vascular endothelial growth factor signaling pathway", "Positive regulation of cell migration involved in sprouting angiogenesis", "Positive regulation of cell morphogenesis involved in differentiation", "Positive regulation of cell population proliferation", "Positive regulation of cell projection organization", "Positive regulation of cell size", "Positive regulation of cell substrate adhesion", "Positive regulation of cell substrate junction organization", "Positive regulation of cellular amide metabolic process", "Positive regulation of cellular amine metabolic process", "Positive regulation of cellular biosynthetic process", "Positive regulation of cellular carbohydrate metabolic process", "Positive regulation of cellular component biogenesis", "Positive regulation of cellular component organization", "Positive regulation of cellular extravasation", "Positive regulation of cellular protein catabolic process", "Positive regulation of cellular respiration", "Positive regulation of cellular response to insulin stimulus", "Positive regulation of cellular response to transforming growth factor beta stimulus", "Positive regulation of centriole replication", "Positive regulation of chemokine c c motif ligand 5 production", "Positive regulation of chemokine c x c motif ligand 2 production", "Positive regulation of chemokine production", "Positive regulation of chemotaxis", "Positive regulation of cholesterol biosynthetic process", "Positive regulation of cholesterol efflux", "Positive regulation of cholesterol metabolic process", "Positive regulation of cholesterol storage", "Positive regulation of chondrocyte differentiation", "Positive regulation of chromatin binding", "Positive regulation of chromatin organization", "Positive regulation of chromosome condensation", "Positive regulation of chromosome organization", "Positive regulation of chromosome segregation", "Positive regulation of chromosome separation", "Positive regulation of cilium assembly", "Positive regulation of circadian rhythm", "Positive regulation of clathrin dependent endocytosis", "Positive regulation of coagulation", "Positive regulation of cold induced thermogenesis", "Positive regulation of collagen metabolic process", "Positive regulation of collateral sprouting", "Positive regulation of complement activation", "Positive regulation of connective tissue replacement", "Positive regulation of cyclase activity", "Positive regulation of cyclic nucleotide phosphodiesterase activity", "Positive regulation of cyclin dependent protein kinase activity", "Positive regulation of cysteine type endopeptidase activity", "Positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Positive regulation of cytokine production", "Positive regulation of cytokine production involved in immune response", "Positive regulation of cytokine production involved in inflammatory response", "Positive regulation of cytokinesis", "Positive regulation of cytoplasmic translation", "Positive regulation of cytoplasmic transport", "Positive regulation of cytoskeleton organization", "Positive regulation of deacetylase activity", "Positive regulation of defense response", "Positive regulation of defense response to virus by host", "Positive regulation of dendrite development", "Positive regulation of dendrite morphogenesis", "Positive regulation of dendritic cell cytokine production", "Positive regulation of dendritic cell differentiation", "Positive regulation of dendritic spine development", "Positive regulation of dendritic spine morphogenesis", "Positive regulation of deoxyribonuclease activity", "Positive regulation of dephosphorylation", "Positive regulation of developmental growth", "Positive regulation of developmental pigmentation", "Positive regulation of developmental process", "Positive regulation of dna binding", "Positive regulation of dna binding transcription factor activity", "Positive regulation of dna biosynthetic process", "Positive regulation of dna catabolic process", "Positive regulation of dna damage response signal transduction by p53 class mediator", "Positive regulation of dna demethylation", "Positive regulation of dna dependent dna replication", "Positive regulation of dna ligation", "Positive regulation of dna metabolic process", "Positive regulation of dna methylation dependent heterochromatin assembly", "Positive regulation of dna recombination", "Positive regulation of dna repair", "Positive regulation of dna replication", "Positive regulation of dna templated transcription elongation", "Positive regulation of dna templated transcription initiation", "Positive regulation of dopamine receptor signaling pathway", "Positive regulation of double strand break repair", "Positive regulation of double strand break repair via homologous recombination", "Positive regulation of double strand break repair via nonhomologous end joining", "Positive regulation of early endosome to late endosome transport", "Positive regulation of embryonic development", "Positive regulation of endocytic recycling", "Positive regulation of endocytosis", "Positive regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Positive regulation of endoplasmic reticulum unfolded protein response", "Positive regulation of endothelial cell apoptotic process", "Positive regulation of endothelial cell chemotaxis", "Positive regulation of endothelial cell chemotaxis by vegf activated vascular endothelial growth factor receptor signaling pathway", "Positive regulation of endothelial cell development", "Positive regulation of endothelial cell differentiation", "Positive regulation of endothelial cell matrix adhesion via fibronectin", "Positive regulation of endothelial cell migration", "Positive regulation of endothelial cell proliferation", "Positive regulation of epidermal cell differentiation", "Positive regulation of epidermis development", "Positive regulation of epithelial cell apoptotic process", "Positive regulation of epithelial cell differentiation", "Positive regulation of epithelial cell migration", "Positive regulation of epithelial cell proliferation", "Positive regulation of epithelial cell proliferation involved in lung morphogenesis", "Positive regulation of epithelial to mesenchymal transition", "Positive regulation of er associated ubiquitin dependent protein catabolic process", "Positive regulation of erad pathway", "Positive regulation of erbb signaling pathway", "Positive regulation of erk1 and erk2 cascade", "Positive regulation of erythrocyte differentiation", "Positive regulation of establishment of protein localization", "Positive regulation of establishment of protein localization to mitochondrion", "Positive regulation of establishment of protein localization to telomere", "Positive regulation of excitatory postsynaptic potential", "Positive regulation of execution phase of apoptosis", "Positive regulation of exocytosis", "Positive regulation of exosomal secretion", "Positive regulation of extracellular matrix assembly", "Positive regulation of extracellular matrix disassembly", "Positive regulation of extracellular matrix organization", "Positive regulation of extrinsic apoptotic signaling pathway", "Positive regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Positive regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Positive regulation of fat cell differentiation", "Positive regulation of fatty acid beta oxidation", "Positive regulation of fatty acid biosynthetic process", "Positive regulation of fatty acid metabolic process", "Positive regulation of fatty acid oxidation", "Positive regulation of fatty acid transport", "Positive regulation of feeding behavior", "Positive regulation of fibroblast growth factor receptor signaling pathway", "Positive regulation of fibroblast migration", "Positive regulation of fibroblast proliferation", "Positive regulation of filopodium assembly", "Positive regulation of focal adhesion assembly", "Positive regulation of g protein coupled receptor signaling pathway", "Positive regulation of g0 to g1 transition", "Positive regulation of g1 s transition of mitotic cell cycle", "Positive regulation of gastrulation", "Positive regulation of gene expression", "Positive regulation of glial cell differentiation", "Positive regulation of glial cell migration", "Positive regulation of glial cell proliferation", "Positive regulation of gliogenesis", "Positive regulation of glucokinase activity", "Positive regulation of gluconeogenesis", "Positive regulation of glucose import", "Positive regulation of glucose metabolic process", "Positive regulation of glucose transmembrane transport", "Positive regulation of glutamate secretion", "Positive regulation of glycogen metabolic process", "Positive regulation of glycolytic process", "Positive regulation of glycoprotein metabolic process", "Positive regulation of golgi to plasma membrane protein transport", "Positive regulation of gonad development", "Positive regulation of granulocyte chemotaxis", "Positive regulation of growth", "Positive regulation of gtpase activity", "Positive regulation of hair follicle development", "Positive regulation of heart growth", "Positive regulation of heart rate", "Positive regulation of helicase activity", "Positive regulation of hematopoietic progenitor cell differentiation", "Positive regulation of hematopoietic stem cell proliferation", "Positive regulation of hemopoiesis", "Positive regulation of heterotypic cell cell adhesion", "Positive regulation of hexokinase activity", "Positive regulation of hippo signaling", "Positive regulation of histone acetylation", "Positive regulation of histone deacetylation", "Positive regulation of histone h3 k27 methylation", "Positive regulation of histone h3 k4 methylation", "Positive regulation of histone h3 k9 acetylation", "Positive regulation of histone h3 k9 methylation", "Positive regulation of histone h4 acetylation", "Positive regulation of histone methylation", "Positive regulation of histone modification", "Positive regulation of histone phosphorylation", "Positive regulation of histone ubiquitination", "Positive regulation of homotypic cell cell adhesion", "Positive regulation of hormone biosynthetic process", "Positive regulation of hormone metabolic process", "Positive regulation of hormone secretion", "Positive regulation of humoral immune response", "Positive regulation of hydrogen peroxide metabolic process", "Positive regulation of hydrolase activity", "Positive regulation of i kappab kinase nf kappab signaling", "Positive regulation of i kappab phosphorylation", "Positive regulation of immune effector process", "Positive regulation of immune response", "Positive regulation of immune system process", "Positive regulation of immunoglobulin production", "Positive regulation of inclusion body assembly", "Positive regulation of inflammatory response", "Positive regulation of inflammatory response to antigenic stimulus", "Positive regulation of innate immune response", "Positive regulation of insulin like growth factor receptor signaling pathway", "Positive regulation of insulin secretion", "Positive regulation of insulin secretion involved in cellular response to glucose stimulus", "Positive regulation of integrin activation", "Positive regulation of integrin mediated signaling pathway", "Positive regulation of interferon alpha production", "Positive regulation of interferon beta production", "Positive regulation of interferon gamma production", "Positive regulation of interleukin 1 beta production", "Positive regulation of interleukin 1 production", "Positive regulation of interleukin 10 production", "Positive regulation of interleukin 12 production", "Positive regulation of interleukin 17 production", "Positive regulation of interleukin 18 production", "Positive regulation of interleukin 2 production", "Positive regulation of interleukin 6 production", "Positive regulation of interleukin 8 production", "Positive regulation of intracellular lipid transport", "Positive regulation of intracellular protein transport", "Positive regulation of intracellular signal transduction", "Positive regulation of intracellular steroid hormone receptor signaling pathway", "Positive regulation of intracellular transport", "Positive regulation of intrinsic apoptotic signaling pathway", "Positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Positive regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Positive regulation of ion transmembrane transport", "Positive regulation of ion transport", "Positive regulation of ire1 mediated unfolded protein response", "Positive regulation of isotype switching", "Positive regulation of isotype switching to iga isotypes", "Positive regulation of isotype switching to igg isotypes", "Positive regulation of jnk cascade", "Positive regulation of jun kinase activity", "Positive regulation of keratinocyte differentiation", "Positive regulation of keratinocyte proliferation", "Positive regulation of kinase activity", "Positive regulation of lamellipodium assembly", "Positive regulation of lamellipodium morphogenesis", "Positive regulation of lamellipodium organization", "Positive regulation of leukocyte adhesion to vascular endothelial cell", "Positive regulation of leukocyte apoptotic process", "Positive regulation of leukocyte cell cell adhesion", "Positive regulation of leukocyte chemotaxis", "Positive regulation of leukocyte degranulation", "Positive regulation of leukocyte mediated immunity", "Positive regulation of leukocyte migration", "Positive regulation of leukocyte proliferation", "Positive regulation of ligase activity", "Positive regulation of lipase activity", "Positive regulation of lipid biosynthetic process", "Positive regulation of lipid catabolic process", "Positive regulation of lipid kinase activity", "Positive regulation of lipid localization", "Positive regulation of lipid metabolic process", "Positive regulation of lipid storage", "Positive regulation of lipid transport", "Positive regulation of lipopolysaccharide mediated signaling pathway", "Positive regulation of lipoprotein particle clearance", "Positive regulation of locomotion", "Positive regulation of long term neuronal synaptic plasticity", "Positive regulation of long term synaptic potentiation", "Positive regulation of low density lipoprotein receptor activity", "Positive regulation of lyase activity", "Positive regulation of lymphocyte anergy", "Positive regulation of lymphocyte apoptotic process", "Positive regulation of lymphocyte chemotaxis", "Positive regulation of lymphocyte differentiation", "Positive regulation of lymphocyte mediated immunity", "Positive regulation of lymphocyte migration", "Positive regulation of macroautophagy", "Positive regulation of macrophage activation", "Positive regulation of macrophage chemotaxis", "Positive regulation of macrophage cytokine production", "Positive regulation of macrophage migration", "Positive regulation of maintenance of sister chromatid cohesion", "Positive regulation of mammary gland epithelial cell proliferation", "Positive regulation of map kinase activity", "Positive regulation of mapk cascade", "Positive regulation of mast cell activation", "Positive regulation of mast cell activation involved in immune response", "Positive regulation of megakaryocyte differentiation", "Positive regulation of meiotic cell cycle", "Positive regulation of meiotic nuclear division", "Positive regulation of membrane depolarization", "Positive regulation of membrane permeability", "Positive regulation of membrane potential", "Positive regulation of membrane protein ectodomain proteolysis", "Positive regulation of mesenchymal cell proliferation", "Positive regulation of mesenchymal stem cell proliferation", "Positive regulation of metalloendopeptidase activity", "Positive regulation of metallopeptidase activity", "Positive regulation of metaphase anaphase transition of cell cycle", "Positive regulation of mhc class i biosynthetic process", "Positive regulation of mhc class ii biosynthetic process", "Positive regulation of microglial cell activation", "Positive regulation of microtubule binding", "Positive regulation of microtubule nucleation", "Positive regulation of microtubule polymerization or depolymerization", "Positive regulation of mirna catabolic process", "Positive regulation of mirna mediated gene silencing by inhibition of translation", "Positive regulation of mirna metabolic process", "Positive regulation of mirna transcription", "Positive regulation of mitochondrial calcium ion concentration", "Positive regulation of mitochondrial depolarization", "Positive regulation of mitochondrial fission", "Positive regulation of mitochondrial membrane potential", "Positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Positive regulation of mitochondrial translation", "Positive regulation of mitochondrion organization", "Positive regulation of mitophagy", "Positive regulation of mitophagy in response to mitochondrial depolarization", "Positive regulation of mitotic cell cycle", "Positive regulation of mitotic cell cycle phase transition", "Positive regulation of mitotic cell cycle spindle assembly checkpoint", "Positive regulation of mitotic nuclear division", "Positive regulation of molecular function", "Positive regulation of monocyte chemotaxis", "Positive regulation of monocyte differentiation", "Positive regulation of mononuclear cell migration", "Positive regulation of monooxygenase activity", "Positive regulation of morphogenesis of an epithelium", "Positive regulation of mrna 3 end processing", "Positive regulation of mrna metabolic process", "Positive regulation of mrna processing", "Positive regulation of mrna splicing via spliceosome", "Positive regulation of multicellular organism growth", "Positive regulation of multicellular organismal process", "Positive regulation of muscle adaptation", "Positive regulation of muscle cell apoptotic process", "Positive regulation of muscle cell differentiation", "Positive regulation of muscle contraction", "Positive regulation of muscle hypertrophy", "Positive regulation of muscle tissue development", "Positive regulation of myelination", "Positive regulation of myeloid cell apoptotic process", "Positive regulation of myeloid cell differentiation", "Positive regulation of myeloid leukocyte cytokine production involved in immune response", "Positive regulation of myeloid leukocyte differentiation", "Positive regulation of myeloid leukocyte mediated immunity", "Positive regulation of myoblast differentiation", "Positive regulation of myoblast fusion", "Positive regulation of myotube differentiation", "Positive regulation of nad p h oxidase activity", "Positive regulation of natural killer cell activation", "Positive regulation of natural killer cell mediated cytotoxicity", "Positive regulation of natural killer cell mediated immunity", "Positive regulation of necrotic cell death", "Positive regulation of nervous system development", "Positive regulation of nervous system process", "Positive regulation of neural precursor cell proliferation", "Positive regulation of neuroblast proliferation", "Positive regulation of neurogenesis", "Positive regulation of neuroinflammatory response", "Positive regulation of neuron apoptotic process", "Positive regulation of neuron death", "Positive regulation of neuron differentiation", "Positive regulation of neuron migration", "Positive regulation of neuron projection arborization", "Positive regulation of neuron projection development", "Positive regulation of neuron projection regeneration", "Positive regulation of neurotransmitter secretion", "Positive regulation of neurotransmitter transport", "Positive regulation of neurotransmitter uptake", "Positive regulation of neurotrophin trk receptor signaling pathway", "Positive regulation of neutrophil migration", "Positive regulation of nf kappab transcription factor activity", "Positive regulation of nik nf kappab signaling", "Positive regulation of nitric oxide metabolic process", "Positive regulation of nitric oxide synthase activity", "Positive regulation of nitric oxide synthase biosynthetic process", "Positive regulation of nk t cell activation", "Positive regulation of nlrp3 inflammasome complex assembly", "Positive regulation of non motile cilium assembly", "Positive regulation of notch signaling pathway", "Positive regulation of nuclear cell cycle dna replication", "Positive regulation of nuclear division", "Positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Positive regulation of nuclease activity", "Positive regulation of nucleobase containing compound metabolic process", "Positive regulation of nucleobase containing compound transport", "Positive regulation of nucleocytoplasmic transport", "Positive regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Positive regulation of nucleotide binding oligomerization domain containing signaling pathway", "Positive regulation of nucleotide biosynthetic process", "Positive regulation of nucleotide metabolic process", "Positive regulation of oligodendrocyte differentiation", "Positive regulation of organ growth", "Positive regulation of organelle assembly", "Positive regulation of organelle organization", "Positive regulation of organic acid transport", "Positive regulation of ossification", "Positive regulation of osteoblast differentiation", "Positive regulation of osteoblast proliferation", "Positive regulation of oxidative stress induced cell death", "Positive regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Positive regulation of oxidoreductase activity", "Positive regulation of p38mapk cascade", "Positive regulation of pathway restricted smad protein phosphorylation", "Positive regulation of pattern recognition receptor signaling pathway", "Positive regulation of peptidase activity", "Positive regulation of peptide secretion", "Positive regulation of peptidyl lysine acetylation", "Positive regulation of peptidyl serine phosphorylation", "Positive regulation of peptidyl threonine phosphorylation", "Positive regulation of peptidyl tyrosine phosphorylation", "Positive regulation of peroxisome proliferator activated receptor signaling pathway", "Positive regulation of phagocytosis", "Positive regulation of phosphatase activity", "Positive regulation of phosphatidylinositol 3 kinase signaling", "Positive regulation of phospholipase activity", "Positive regulation of phospholipid biosynthetic process", "Positive regulation of phospholipid metabolic process", "Positive regulation of phosphoprotein phosphatase activity", "Positive regulation of phosphorus metabolic process", "Positive regulation of pinocytosis", "Positive regulation of plasma membrane bounded cell projection assembly", "Positive regulation of plasminogen activation", "Positive regulation of platelet aggregation", "Positive regulation of podosome assembly", "Positive regulation of posttranscriptional gene silencing", "Positive regulation of potassium ion import across plasma membrane", "Positive regulation of potassium ion transmembrane transporter activity", "Positive regulation of potassium ion transport", "Positive regulation of production of mirnas involved in gene silencing by mirna", "Positive regulation of production of molecular mediator of immune response", "Positive regulation of programmed necrotic cell death", "Positive regulation of prostaglandin biosynthetic process", "Positive regulation of proteasomal ubiquitin dependent protein catabolic process", "Positive regulation of protein acetylation", "Positive regulation of protein autophosphorylation", "Positive regulation of protein binding", "Positive regulation of protein catabolic process", "Positive regulation of protein catabolic process in the vacuole", "Positive regulation of protein containing complex assembly", "Positive regulation of protein containing complex disassembly", "Positive regulation of protein deacetylation", "Positive regulation of protein dephosphorylation", "Positive regulation of protein depolymerization", "Positive regulation of protein deubiquitination", "Positive regulation of protein exit from endoplasmic reticulum", "Positive regulation of protein export from nucleus", "Positive regulation of protein glycosylation", "Positive regulation of protein import", "Positive regulation of protein k63 linked ubiquitination", "Positive regulation of protein kinase a signaling", "Positive regulation of protein kinase activity", "Positive regulation of protein kinase b signaling", "Positive regulation of protein localization", "Positive regulation of protein localization to cell cortex", "Positive regulation of protein localization to cell periphery", "Positive regulation of protein localization to cell surface", "Positive regulation of protein localization to centrosome", "Positive regulation of protein localization to early endosome", "Positive regulation of protein localization to membrane", "Positive regulation of protein localization to nucleus", "Positive regulation of protein maturation", "Positive regulation of protein metabolic process", "Positive regulation of protein modification by small protein conjugation or removal", "Positive regulation of protein modification process", "Positive regulation of protein monoubiquitination", "Positive regulation of protein phosphorylation", "Positive regulation of protein polymerization", "Positive regulation of protein polyubiquitination", "Positive regulation of protein secretion", "Positive regulation of protein serine threonine kinase activity", "Positive regulation of protein sumoylation", "Positive regulation of protein targeting to membrane", "Positive regulation of protein tyrosine kinase activity", "Positive regulation of proteolysis", "Positive regulation of proteolysis involved in cellular protein catabolic process", "Positive regulation of pseudopodium assembly", "Positive regulation of reactive oxygen species biosynthetic process", "Positive regulation of reactive oxygen species metabolic process", "Positive regulation of receptor binding", "Positive regulation of receptor catabolic process", "Positive regulation of receptor clustering", "Positive regulation of receptor internalization", "Positive regulation of receptor mediated endocytosis", "Positive regulation of receptor recycling", "Positive regulation of receptor signaling pathway via stat", "Positive regulation of regulated secretory pathway", "Positive regulation of release of cytochrome c from mitochondria", "Positive regulation of release of sequestered calcium ion into cytosol", "Positive regulation of renal sodium excretion", "Positive regulation of reproductive process", "Positive regulation of respiratory burst", "Positive regulation of response to biotic stimulus", "Positive regulation of response to cytokine stimulus", "Positive regulation of response to dna damage stimulus", "Positive regulation of response to endoplasmic reticulum stress", "Positive regulation of response to external stimulus", "Positive regulation of response to tumor cell", "Positive regulation of response to wounding", "Positive regulation of retinoic acid receptor signaling pathway", "Positive regulation of rho protein signal transduction", "Positive regulation of rig i signaling pathway", "Positive regulation of rna binding", "Positive regulation of rna export from nucleus", "Positive regulation of rna metabolic process", "Positive regulation of rna polymerase ii transcription preinitiation complex assembly", "Positive regulation of rna splicing", "Positive regulation of rrna processing", "Positive regulation of ruffle assembly", "Positive regulation of ryanodine sensitive calcium release channel activity", "Positive regulation of secretion", "Positive regulation of sequestering of calcium ion", "Positive regulation of sequestering of triglyceride", "Positive regulation of signal transduction by p53 class mediator", "Positive regulation of signaling", "Positive regulation of signaling receptor activity", "Positive regulation of sister chromatid cohesion", "Positive regulation of skeletal muscle tissue development", "Positive regulation of smad protein signal transduction", "Positive regulation of small gtpase mediated signal transduction", "Positive regulation of small molecule metabolic process", "Positive regulation of smooth muscle cell apoptotic process", "Positive regulation of smooth muscle cell differentiation", "Positive regulation of smooth muscle cell migration", "Positive regulation of smooth muscle cell proliferation", "Positive regulation of smooth muscle contraction", "Positive regulation of smoothened signaling pathway", "Positive regulation of sodium ion transmembrane transport", "Positive regulation of sodium ion transmembrane transporter activity", "Positive regulation of sodium ion transport", "Positive regulation of spindle assembly", "Positive regulation of sprouting angiogenesis", "Positive regulation of stem cell differentiation", "Positive regulation of stem cell proliferation", "Positive regulation of steroid biosynthetic process", "Positive regulation of steroid hormone biosynthetic process", "Positive regulation of steroid metabolic process", "Positive regulation of sterol transport", "Positive regulation of store operated calcium channel activity", "Positive regulation of stress activated protein kinase signaling cascade", "Positive regulation of stress fiber assembly", "Positive regulation of striated muscle cell apoptotic process", "Positive regulation of striated muscle cell differentiation", "Positive regulation of striated muscle contraction", "Positive regulation of substrate adhesion dependent cell spreading", "Positive regulation of supramolecular fiber organization", "Positive regulation of synapse assembly", "Positive regulation of synaptic plasticity", "Positive regulation of synaptic transmission", "Positive regulation of synaptic transmission gabaergic", "Positive regulation of synaptic transmission glutamatergic", "Positive regulation of synaptic vesicle endocytosis", "Positive regulation of synaptic vesicle recycling", "Positive regulation of syncytium formation by plasma membrane fusion", "Positive regulation of systemic arterial blood pressure", "Positive regulation of t cell apoptotic process", "Positive regulation of t cell cytokine production", "Positive regulation of t cell differentiation in thymus", "Positive regulation of t cell mediated cytotoxicity", "Positive regulation of t cell mediated immune response to tumor cell", "Positive regulation of t cell mediated immunity", "Positive regulation of t cell migration", "Positive regulation of t cell proliferation", "Positive regulation of t cell receptor signaling pathway", "Positive regulation of t cell tolerance induction", "Positive regulation of t helper 1 cell differentiation", "Positive regulation of t helper 2 cell cytokine production", "Positive regulation of t helper cell differentiation", "Positive regulation of tau protein kinase activity", "Positive regulation of telomerase activity", "Positive regulation of telomerase rna localization to cajal body", "Positive regulation of telomere capping", "Positive regulation of telomere maintenance", "Positive regulation of telomere maintenance via telomere lengthening", "Positive regulation of tissue remodeling", "Positive regulation of tolerance induction", "Positive regulation of toll like receptor 3 signaling pathway", "Positive regulation of toll like receptor 9 signaling pathway", "Positive regulation of toll like receptor signaling pathway", "Positive regulation of tor signaling", "Positive regulation of torc1 signaling", "Positive regulation of transcription by rna polymerase i", "Positive regulation of transcription by rna polymerase ii", "Positive regulation of transcription by rna polymerase iii", "Positive regulation of transcription elongation from rna polymerase ii promoter", "Positive regulation of transcription from rna polymerase ii promoter in response to endoplasmic reticulum stress", "Positive regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Positive regulation of transcription from rna polymerase ii promoter in response to stress", "Positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus", "Positive regulation of transcription of notch receptor target", "Positive regulation of transcription of nucleolar large rrna by rna polymerase i", "Positive regulation of transcription regulatory region dna binding", "Positive regulation of transferase activity", "Positive regulation of translation", "Positive regulation of translation in response to endoplasmic reticulum stress", "Positive regulation of translation in response to stress", "Positive regulation of translational initiation", "Positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Positive regulation of transmembrane transport", "Positive regulation of transmission of nerve impulse", "Positive regulation of transport", "Positive regulation of transporter activity", "Positive regulation of triglyceride biosynthetic process", "Positive regulation of triglyceride metabolic process", "Positive regulation of trophoblast cell migration", "Positive regulation of tumor necrosis factor mediated signaling pathway", "Positive regulation of tumor necrosis factor superfamily cytokine production", "Positive regulation of type 2 immune response", "Positive regulation of type i interferon mediated signaling pathway", "Positive regulation of type i interferon production", "Positive regulation of tyrosine phosphorylation of stat protein", "Positive regulation of ubiquitin dependent protein catabolic process", "Positive regulation of ubiquitin protein ligase activity", "Positive regulation of ubiquitin protein transferase activity", "Positive regulation of unsaturated fatty acid biosynthetic process", "Positive regulation of urine volume", "Positive regulation of vacuole organization", "Positive regulation of vascular associated smooth muscle cell apoptotic process", "Positive regulation of vascular associated smooth muscle cell differentiation", "Positive regulation of vascular associated smooth muscle cell proliferation", "Positive regulation of vascular endothelial cell proliferation", "Positive regulation of vascular endothelial growth factor signaling pathway", "Positive regulation of vascular permeability", "Positive regulation of vasculature development", "Positive regulation of vasculogenesis", "Positive regulation of vasoconstriction", "Positive regulation of vesicle fusion", "Positive regulation of viral genome replication", "Positive regulation of viral life cycle", "Positive regulation of viral process", "Positive regulation of vitamin d receptor signaling pathway", "Positive regulation of voltage gated calcium channel activity", "Positive regulation of wnt signaling pathway", "Positive regulation of wound healing", "Positive regulation of wound healing spreading of epidermal cells", "Positive t cell selection", "Post anal tail morphogenesis", "Post chaperonin tubulin folding pathway", "Post embryonic animal morphogenesis", "Post embryonic animal organ development", "Post embryonic animal organ morphogenesis", "Post embryonic camera type eye development", "Post embryonic development", "Post embryonic eye morphogenesis", "Post golgi vesicle mediated transport", "Post translational protein modification", "Postreplication repair", "Postsynapse organization", "Postsynapse to nucleus signaling pathway", "Postsynaptic actin cytoskeleton organization", "Postsynaptic cytoskeleton organization", "Postsynaptic membrane organization", "Postsynaptic modulation of chemical synaptic transmission", "Postsynaptic neurotransmitter receptor internalization", "Postsynaptic signal transduction", "Postsynaptic specialization organization", "Posttranscriptional regulation of gene expression", "Posttranslational protein targeting to endoplasmic reticulum membrane", "Posttranslational protein targeting to membrane translocation", "Potassium ion homeostasis", "Potassium ion import across plasma membrane", "Potassium ion transport", "Pre mirna processing", "Prenylation", "Presynapse organization", "Presynaptic active zone organization", "Presynaptic endocytosis", "Presynaptic modulation of chemical synaptic transmission", "Prevention of polyspermy", "Primary alcohol biosynthetic process", "Primary alcohol catabolic process", "Primary alcohol metabolic process", "Primary amino compound biosynthetic process", "Primary amino compound metabolic process", "Primary mirna processing", "Primitive hemopoiesis", "Pro b cell differentiation", "Process utilizing autophagic mechanism", "Production of molecular mediator involved in inflammatory response", "Production of molecular mediator of immune response", "Production of sirna involved in rna interference", "Progesterone biosynthetic process", "Progesterone metabolic process", "Progesterone receptor signaling pathway", "Programmed cell death", "Programmed cell death in response to reactive oxygen species", "Programmed cell death involved in cell development", "Programmed necrotic cell death", "Prolactin secretion", "Proline metabolic process", "Pronephros development", "Proprioception", "Prostaglandin transport", "Prostanoid biosynthetic process", "Prostanoid metabolic process", "Prostate gland development", "Prostate gland growth", "Prosthetic group metabolic process", "Proteasomal protein catabolic process", "Proteasome assembly", "Proteasome mediated ubiquitin dependent protein catabolic process", "Protection from natural killer cell mediated cytotoxicity", "Protection from non homologous end joining at telomere", "Protein acetylation", "Protein activation cascade", "Protein acylation", "Protein adp ribosylation", "Protein auto adp ribosylation", "Protein autophosphorylation", "Protein autoprocessing", "Protein autoubiquitination", "Protein catabolic process", "Protein catabolic process in the vacuole", "Protein complex oligomerization", "Protein containing complex disassembly", "Protein containing complex localization", "Protein containing complex organization", "Protein containing complex remodeling", "Protein de adp ribosylation", "Protein deglycosylation", "Protein demannosylation", "Protein demethylation", "Protein deneddylation", "Protein depalmitoylation", "Protein dephosphorylation", "Protein depolymerization", "Protein destabilization", "Protein desumoylation", "Protein deubiquitination involved in ubiquitin dependent protein catabolic process", "Protein dna complex assembly", "Protein dna complex disassembly", "Protein dna complex subunit organization", "Protein dna covalent cross linking repair", "Protein exit from endoplasmic reticulum", "Protein export from nucleus", "Protein folding", "Protein folding in endoplasmic reticulum", "Protein geranylgeranylation", "Protein heterooligomerization", "Protein heterotetramerization", "Protein hexamerization", "Protein homooligomerization", "Protein homotetramerization", "Protein hydroxylation", "Protein import", "Protein import into mitochondrial matrix", "Protein import into peroxisome matrix", "Protein import into peroxisome membrane", "Protein insertion into er membrane", "Protein insertion into er membrane by stop transfer membrane anchor sequence", "Protein insertion into membrane", "Protein insertion into mitochondrial inner membrane", "Protein insertion into mitochondrial membrane involved in apoptotic signaling pathway", "Protein k11 linked ubiquitination", "Protein k27 linked ubiquitination", "Protein k29 linked ubiquitination", "Protein k48 linked deubiquitination", "Protein k48 linked ubiquitination", "Protein k6 linked ubiquitination", "Protein k63 linked deubiquitination", "Protein k63 linked ubiquitination", "Protein kinase a signaling", "Protein kinase b signaling", "Protein kinase c signaling", "Protein lipid complex assembly", "Protein lipid complex subunit organization", "Protein localization to adherens junction", "Protein localization to axon", "Protein localization to basolateral plasma membrane", "Protein localization to cell cell junction", "Protein localization to cell cortex", "Protein localization to cell junction", "Protein localization to cell periphery", "Protein localization to cell surface", "Protein localization to chromatin", "Protein localization to chromosome", "Protein localization to chromosome centromeric region", "Protein localization to chromosome telomeric region", "Protein localization to ciliary membrane", "Protein localization to cilium", "Protein localization to condensed chromosome", "Protein localization to cytoplasmic stress granule", "Protein localization to cytoskeleton", "Protein localization to early endosome", "Protein localization to endoplasmic reticulum", "Protein localization to endoplasmic reticulum exit site", "Protein localization to endosome", "Protein localization to extracellular region", "Protein localization to golgi apparatus", "Protein localization to lysosome", "Protein localization to membrane raft", "Protein localization to microtubule", "Protein localization to microtubule end", "Protein localization to microtubule organizing center", "Protein localization to mitochondrion", "Protein localization to nuclear body", "Protein localization to nuclear envelope", "Protein localization to nucleolus", "Protein localization to nucleoplasm", "Protein localization to nucleus", "Protein localization to organelle", "Protein localization to phagophore assembly site", "Protein localization to plasma membrane", "Protein localization to postsynapse", "Protein localization to presynapse", "Protein localization to synapse", "Protein localization to vacuole", "Protein mannosylation", "Protein maturation", "Protein maturation by 4fe 4s cluster transfer", "Protein maturation by iron sulfur cluster transfer", "Protein maturation by protein folding", "Protein methylation", "Protein modification by small protein conjugation", "Protein modification by small protein conjugation or removal", "Protein modification by small protein removal", "Protein monoubiquitination", "Protein n linked glycosylation", "Protein neddylation", "Protein nitrosylation", "Protein o linked fucosylation", "Protein o linked glycosylation", "Protein o linked glycosylation via serine", "Protein o linked glycosylation via threonine", "Protein o linked mannosylation", "Protein oxidation", "Protein palmitoylation", "Protein peptidyl prolyl isomerization", "Protein poly adp ribosylation", "Protein polyglutamylation", "Protein polymerization", "Protein polyubiquitination", "Protein polyufmylation", "Protein processing", "Protein processing involved in protein targeting to mitochondrion", "Protein quality control for misfolded or incompletely synthesized proteins", "Protein refolding", "Protein repair", "Protein retention in er lumen", "Protein retention in golgi apparatus", "Protein stabilization", "Protein sumoylation", "Protein targeting", "Protein targeting to lysosome", "Protein targeting to membrane", "Protein targeting to mitochondrion", "Protein targeting to peroxisome", "Protein targeting to vacuole", "Protein tetramerization", "Protein transmembrane import into intracellular organelle", "Protein transmembrane transport", "Protein transport along microtubule", "Protein transport to vacuole involved in ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Protein trimerization", "Protein ufmylation", "Proteoglycan biosynthetic process", "Proteoglycan metabolic process", "Proteolysis", "Proton transmembrane transport", "Proton transporting two sector atpase complex assembly", "Proton transporting v type atpase complex assembly", "Protoporphyrinogen ix biosynthetic process", "Protoporphyrinogen ix metabolic process", "Proximal distal pattern formation", "Proximal distal pattern formation involved in nephron development", "Proximal tubule development", "Pseudopodium organization", "Pseudouridine synthesis", "Pteridine containing compound biosynthetic process", "Pteridine containing compound metabolic process", "Purine containing compound biosynthetic process", "Purine containing compound catabolic process", "Purine containing compound metabolic process", "Purine containing compound salvage", "Purine containing compound transmembrane transport", "Purine deoxyribonucleoside metabolic process", "Purine deoxyribonucleoside monophosphate catabolic process", "Purine deoxyribonucleoside monophosphate metabolic process", "Purine deoxyribonucleoside triphosphate metabolic process", "Purine deoxyribonucleotide biosynthetic process", "Purine deoxyribonucleotide catabolic process", "Purine deoxyribonucleotide metabolic process", "Purine nucleobase biosynthetic process", "Purine nucleobase metabolic process", "Purine nucleoside biosynthetic process", "Purine nucleoside catabolic process", "Purine nucleoside diphosphate biosynthetic process", "Purine nucleoside metabolic process", "Purine nucleoside monophosphate biosynthetic process", "Purine nucleoside monophosphate catabolic process", "Purine nucleoside monophosphate metabolic process", "Purine nucleoside triphosphate catabolic process", "Purine nucleotide catabolic process", "Purine nucleotide salvage", "Purine nucleotide transport", "Purine ribonucleoside catabolic process", "Purine ribonucleoside metabolic process", "Purine ribonucleoside salvage", "Purine ribonucleotide salvage", "Purinergic nucleotide receptor signaling pathway", "Pyramidal neuron development", "Pyramidal neuron differentiation", "Pyridine containing compound biosynthetic process", "Pyridine containing compound catabolic process", "Pyridine containing compound metabolic process", "Pyridine nucleotide biosynthetic process", "Pyridine nucleotide metabolic process", "Pyrimidine containing compound biosynthetic process", "Pyrimidine containing compound catabolic process", "Pyrimidine containing compound metabolic process", "Pyrimidine containing compound salvage", "Pyrimidine containing compound transmembrane transport", "Pyrimidine deoxyribonucleoside metabolic process", "Pyrimidine deoxyribonucleoside monophosphate biosynthetic process", "Pyrimidine deoxyribonucleoside monophosphate metabolic process", "Pyrimidine deoxyribonucleoside triphosphate metabolic process", "Pyrimidine deoxyribonucleotide biosynthetic process", "Pyrimidine deoxyribonucleotide metabolic process", "Pyrimidine dimer repair", "Pyrimidine nucleobase biosynthetic process", "Pyrimidine nucleobase catabolic process", "Pyrimidine nucleobase metabolic process", "Pyrimidine nucleoside diphosphate biosynthetic process", "Pyrimidine nucleoside diphosphate metabolic process", "Pyrimidine nucleoside metabolic process", "Pyrimidine nucleoside monophosphate biosynthetic process", "Pyrimidine nucleoside monophosphate metabolic process", "Pyrimidine nucleoside transport", "Pyrimidine nucleoside triphosphate biosynthetic process", "Pyrimidine nucleoside triphosphate metabolic process", "Pyrimidine nucleotide catabolic process", "Pyrimidine nucleotide metabolic process", "Pyrimidine ribonucleoside diphosphate metabolic process", "Pyrimidine ribonucleoside monophosphate metabolic process", "Pyrimidine ribonucleoside triphosphate biosynthetic process", "Pyrimidine ribonucleoside triphosphate metabolic process", "Pyrimidine ribonucleotide biosynthetic process", "Pyrimidine ribonucleotide metabolic process", "Pyroptosis", "Pyruvate metabolic process", "Quaternary ammonium group transport", "Quinone metabolic process", "R loop disassembly", "Rab protein signal transduction", "Rac protein signal transduction", "Radial glial cell differentiation", "Rap protein signal transduction", "Ras protein signal transduction", "Reactive nitrogen species metabolic process", "Reactive oxygen species biosynthetic process", "Reactive oxygen species metabolic process", "Receptor catabolic process", "Receptor clustering", "Receptor diffusion trapping", "Receptor internalization", "Receptor localization to synapse", "Receptor mediated endocytosis", "Receptor mediated endocytosis involved in cholesterol transport", "Receptor mediated virion attachment to host cell", "Receptor metabolic process", "Receptor recycling", "Receptor signaling pathway via stat", "Recognition of apoptotic cell", "Recombinational repair", "Reelin mediated signaling pathway", "Reflex", "Regeneration", "Regionalization", "Regulated exocytosis", "Regulation by virus of viral protein levels in host cell", "Regulation of 3 utr mediated mrna stabilization", "Regulation of actin cytoskeleton reorganization", "Regulation of actin filament based movement", "Regulation of actin filament based process", "Regulation of actin filament bundle assembly", "Regulation of actin filament length", "Regulation of actin filament organization", "Regulation of actin nucleation", "Regulation of action potential", "Regulation of activin receptor signaling pathway", "Regulation of actomyosin structure organization", "Regulation of acute inflammatory response", "Regulation of acute inflammatory response to antigenic stimulus", "Regulation of acyl coa biosynthetic process", "Regulation of adaptive immune response", "Regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Regulation of adenylate cyclase activity", "Regulation of adherens junction organization", "Regulation of adipose tissue development", "Regulation of aerobic respiration", "Regulation of alcohol biosynthetic process", "Regulation of alpha beta t cell activation", "Regulation of alpha beta t cell differentiation", "Regulation of alternative mrna splicing via spliceosome", "Regulation of amino acid transmembrane transport", "Regulation of amino acid transport", "Regulation of amyloid beta clearance", "Regulation of amyloid fibril formation", "Regulation of amyloid precursor protein catabolic process", "Regulation of anaphase promoting complex dependent catabolic process", "Regulation of anatomical structure morphogenesis", "Regulation of anatomical structure size", "Regulation of androgen receptor signaling pathway", "Regulation of animal organ formation", "Regulation of animal organ morphogenesis", "Regulation of anion channel activity", "Regulation of anion transmembrane transport", "Regulation of anion transport", "Regulation of anoikis", "Regulation of antigen receptor mediated signaling pathway", "Regulation of apoptotic cell clearance", "Regulation of apoptotic dna fragmentation", "Regulation of apoptotic process involved in development", "Regulation of apoptotic signaling pathway", "Regulation of appetite", "Regulation of arachidonic acid secretion", "Regulation of arp2 3 complex mediated actin nucleation", "Regulation of aspartic type endopeptidase activity involved in amyloid precursor protein catabolic process", "Regulation of aspartic type peptidase activity", "Regulation of astrocyte differentiation", "Regulation of asymmetric cell division", "Regulation of atp biosynthetic process", "Regulation of atp dependent activity", "Regulation of atp metabolic process", "Regulation of atpase coupled calcium transmembrane transporter activity", "Regulation of atrial cardiac muscle cell membrane repolarization", "Regulation of attachment of spindle microtubules to kinetochore", "Regulation of autophagy", "Regulation of autophagy of mitochondrion", "Regulation of autophagy of mitochondrion in response to mitochondrial depolarization", "Regulation of axon diameter", "Regulation of axon guidance", "Regulation of axonogenesis", "Regulation of b cell activation", "Regulation of b cell apoptotic process", "Regulation of b cell differentiation", "Regulation of b cell mediated immunity", "Regulation of b cell proliferation", "Regulation of b cell receptor signaling pathway", "Regulation of barbed end actin filament capping", "Regulation of behavior", "Regulation of bicellular tight junction assembly", "Regulation of bile acid biosynthetic process", "Regulation of bile acid metabolic process", "Regulation of bile acid secretion", "Regulation of binding", "Regulation of biological process involved in symbiotic interaction", "Regulation of biomineralization", "Regulation of blood brain barrier permeability", "Regulation of blood circulation", "Regulation of blood pressure", "Regulation of bmp signaling pathway", "Regulation of body fluid levels", "Regulation of bone mineralization", "Regulation of bone mineralization involved in bone maturation", "Regulation of bone remodeling", "Regulation of bone resorption", "Regulation of branching involved in lung morphogenesis", "Regulation of branching morphogenesis of a nerve", "Regulation of brown fat cell differentiation", "Regulation of calcineurin mediated signaling", "Regulation of calcium ion dependent exocytosis", "Regulation of calcium ion export across plasma membrane", "Regulation of calcium ion import", "Regulation of calcium ion transmembrane transport", "Regulation of calcium ion transmembrane transporter activity", "Regulation of calcium ion transport", "Regulation of calcium ion transport into cytosol", "Regulation of calcium mediated signaling", "Regulation of camp dependent protein kinase activity", "Regulation of camp mediated signaling", "Regulation of canonical wnt signaling pathway", "Regulation of carbohydrate biosynthetic process", "Regulation of carbohydrate catabolic process", "Regulation of carbohydrate metabolic process", "Regulation of cardiac conduction", "Regulation of cardiac muscle adaptation", "Regulation of cardiac muscle cell action potential", "Regulation of cardiac muscle cell action potential involved in regulation of contraction", "Regulation of cardiac muscle cell membrane potential", "Regulation of cardiac muscle cell membrane repolarization", "Regulation of cardiac muscle cell proliferation", "Regulation of cardiac muscle contraction", "Regulation of cardiac muscle contraction by calcium ion signaling", "Regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion", "Regulation of cardioblast differentiation", "Regulation of cardiocyte differentiation", "Regulation of cartilage development", "Regulation of catabolic process", "Regulation of catecholamine metabolic process", "Regulation of cation channel activity", "Regulation of cation transmembrane transport", "Regulation of caveolin mediated endocytosis", "Regulation of cd4 positive alpha beta t cell activation", "Regulation of cd4 positive alpha beta t cell differentiation", "Regulation of cd40 signaling pathway", "Regulation of cd8 positive alpha beta t cell activation", "Regulation of cd8 positive alpha beta t cell differentiation", "Regulation of cell activation", "Regulation of cell adhesion", "Regulation of cell adhesion mediated by integrin", "Regulation of cell aging", "Regulation of cell cell adhesion", "Regulation of cell cell adhesion mediated by cadherin", "Regulation of cell cell adhesion mediated by integrin", "Regulation of cell communication by electrical coupling", "Regulation of cell communication by electrical coupling involved in cardiac conduction", "Regulation of cell cycle", "Regulation of cell cycle checkpoint", "Regulation of cell cycle g1 s phase transition", "Regulation of cell cycle g2 m phase transition", "Regulation of cell cycle phase transition", "Regulation of cell cycle process", "Regulation of cell death", "Regulation of cell development", "Regulation of cell differentiation", "Regulation of cell division", "Regulation of cell growth involved in cardiac muscle cell development", "Regulation of cell junction assembly", "Regulation of cell killing", "Regulation of cell matrix adhesion", "Regulation of cell maturation", "Regulation of cell migration involved in sprouting angiogenesis", "Regulation of cell morphogenesis", "Regulation of cell morphogenesis involved in differentiation", "Regulation of cell population proliferation", "Regulation of cell projection assembly", "Regulation of cell projection organization", "Regulation of cell projection size", "Regulation of cell proliferation involved in kidney development", "Regulation of cell shape", "Regulation of cell size", "Regulation of cell substrate adhesion", "Regulation of cell substrate junction organization", "Regulation of cellular amide metabolic process", "Regulation of cellular amine metabolic process", "Regulation of cellular amino acid metabolic process", "Regulation of cellular carbohydrate catabolic process", "Regulation of cellular carbohydrate metabolic process", "Regulation of cellular component biogenesis", "Regulation of cellular component movement", "Regulation of cellular component size", "Regulation of cellular extravasation", "Regulation of cellular ketone metabolic process", "Regulation of cellular localization", "Regulation of cellular macromolecule biosynthetic process", "Regulation of cellular ph", "Regulation of cellular protein catabolic process", "Regulation of cellular respiration", "Regulation of cellular response to growth factor stimulus", "Regulation of cellular response to heat", "Regulation of cellular response to hypoxia", "Regulation of cellular response to insulin stimulus", "Regulation of cellular response to osmotic stress", "Regulation of cellular response to stress", "Regulation of cellular response to transforming growth factor beta stimulus", "Regulation of cellular response to vascular endothelial growth factor stimulus", "Regulation of centriole replication", "Regulation of centrosome cycle", "Regulation of chaperone mediated autophagy", "Regulation of chemotaxis", "Regulation of chloride transport", "Regulation of cholesterol biosynthetic process", "Regulation of cholesterol efflux", "Regulation of cholesterol esterification", "Regulation of cholesterol metabolic process", "Regulation of chondrocyte development", "Regulation of chondrocyte differentiation", "Regulation of chromatin assembly", "Regulation of chromatin assembly or disassembly", "Regulation of chromatin binding", "Regulation of chromatin organization", "Regulation of chromosome condensation", "Regulation of chromosome organization", "Regulation of chromosome segregation", "Regulation of chromosome separation", "Regulation of cilium assembly", "Regulation of cilium beat frequency", "Regulation of cilium beat frequency involved in ciliary motility", "Regulation of cilium dependent cell motility", "Regulation of cilium movement", "Regulation of circadian rhythm", "Regulation of clathrin dependent endocytosis", "Regulation of coagulation", "Regulation of collagen fibril organization", "Regulation of collagen metabolic process", "Regulation of collateral sprouting", "Regulation of complement activation", "Regulation of complement dependent cytotoxicity", "Regulation of connective tissue replacement", "Regulation of core promoter binding", "Regulation of corticotropin secretion", "Regulation of cyclase activity", "Regulation of cyclic nucleotide phosphodiesterase activity", "Regulation of cyclin dependent protein kinase activity", "Regulation of cysteine type endopeptidase activity", "Regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Regulation of cysteine type endopeptidase activity involved in execution phase of apoptosis", "Regulation of cytokinesis", "Regulation of cytoplasmic mrna processing body assembly", "Regulation of cytoplasmic translation", "Regulation of cytoplasmic translational elongation", "Regulation of cytoplasmic translational initiation", "Regulation of cytoplasmic transport", "Regulation of cytoskeleton organization", "Regulation of cytosolic calcium ion concentration", "Regulation of deacetylase activity", "Regulation of defense response", "Regulation of defense response to bacterium", "Regulation of defense response to virus", "Regulation of defense response to virus by host", "Regulation of delayed rectifier potassium channel activity", "Regulation of dendrite development", "Regulation of dendrite extension", "Regulation of dendrite morphogenesis", "Regulation of dendritic cell chemotaxis", "Regulation of dendritic cell differentiation", "Regulation of dendritic spine development", "Regulation of dendritic spine maintenance", "Regulation of dendritic spine morphogenesis", "Regulation of deoxyribonuclease activity", "Regulation of dephosphorylation", "Regulation of developmental growth", "Regulation of digestive system process", "Regulation of dna binding", "Regulation of dna binding transcription factor activity", "Regulation of dna biosynthetic process", "Regulation of dna catabolic process", "Regulation of dna damage checkpoint", "Regulation of dna damage response signal transduction by p53 class mediator", "Regulation of dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator", "Regulation of dna demethylation", "Regulation of dna dependent dna replication", "Regulation of dna dependent dna replication initiation", "Regulation of dna directed dna polymerase activity", "Regulation of dna duplex unwinding", "Regulation of dna helicase activity", "Regulation of dna ligation", "Regulation of dna metabolic process", "Regulation of dna methylation", "Regulation of dna methylation dependent heterochromatin assembly", "Regulation of dna primase activity", "Regulation of dna recombination", "Regulation of dna repair", "Regulation of dna replication", "Regulation of dna strand elongation", "Regulation of dna templated transcription elongation", "Regulation of dna templated transcription in response to stress", "Regulation of dna templated transcription initiation", "Regulation of dna topoisomerase atp hydrolyzing activity", "Regulation of dopamine receptor signaling pathway", "Regulation of dopamine uptake involved in synaptic transmission", "Regulation of double strand break repair", "Regulation of double strand break repair via homologous recombination", "Regulation of double strand break repair via nonhomologous end joining", "Regulation of early endosome to late endosome transport", "Regulation of electron transfer activity", "Regulation of embryonic development", "Regulation of endocrine process", "Regulation of endocytic recycling", "Regulation of endocytosis", "Regulation of endodeoxyribonuclease activity", "Regulation of endodermal cell differentiation", "Regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Regulation of endoplasmic reticulum tubular network organization", "Regulation of endoplasmic reticulum unfolded protein response", "Regulation of endosome to plasma membrane protein transport", "Regulation of endothelial cell chemotaxis", "Regulation of endothelial cell development", "Regulation of endothelial cell differentiation", "Regulation of endothelial cell migration", "Regulation of entry of bacterium into host cell", "Regulation of epidermal growth factor activated receptor activity", "Regulation of epidermis development", "Regulation of epithelial cell apoptotic process", "Regulation of epithelial cell differentiation", "Regulation of epithelial cell differentiation involved in kidney development", "Regulation of epithelial cell migration", "Regulation of epithelial cell proliferation involved in lung morphogenesis", "Regulation of epithelial to mesenchymal transition", "Regulation of er associated ubiquitin dependent protein catabolic process", "Regulation of er to golgi vesicle mediated transport", "Regulation of erad pathway", "Regulation of erbb signaling pathway", "Regulation of erythrocyte differentiation", "Regulation of establishment of planar polarity", "Regulation of establishment of protein localization", "Regulation of establishment of protein localization to chromosome", "Regulation of establishment of protein localization to mitochondrion", "Regulation of establishment or maintenance of cell polarity", "Regulation of excretion", "Regulation of execution phase of apoptosis", "Regulation of exit from mitosis", "Regulation of exocytosis", "Regulation of exosomal secretion", "Regulation of extent of cell growth", "Regulation of extracellular matrix assembly", "Regulation of extracellular matrix disassembly", "Regulation of extracellular matrix organization", "Regulation of extrinsic apoptotic signaling pathway", "Regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Regulation of fat cell differentiation", "Regulation of fat cell proliferation", "Regulation of fatty acid beta oxidation", "Regulation of fatty acid biosynthetic process", "Regulation of fatty acid metabolic process", "Regulation of fatty acid oxidation", "Regulation of fatty acid transport", "Regulation of fc gamma receptor signaling pathway involved in phagocytosis", "Regulation of fc receptor mediated stimulatory signaling pathway", "Regulation of feeding behavior", "Regulation of fertilization", "Regulation of fibroblast growth factor receptor signaling pathway", "Regulation of fibroblast migration", "Regulation of filopodium assembly", "Regulation of focal adhesion disassembly", "Regulation of g protein coupled receptor signaling pathway", "Regulation of g0 to g1 transition", "Regulation of gamma aminobutyric acid secretion", "Regulation of gastrulation", "Regulation of gene expression by genomic imprinting", "Regulation of gene expression epigenetic", "Regulation of gene silencing by rna", "Regulation of generation of precursor metabolites and energy", "Regulation of genetic imprinting", "Regulation of germ cell proliferation", "Regulation of germinal center formation", "Regulation of glial cell apoptotic process", "Regulation of glial cell differentiation", "Regulation of glial cell migration", "Regulation of glial cell proliferation", "Regulation of gliogenesis", "Regulation of glucagon secretion", "Regulation of glucan biosynthetic process", "Regulation of glucocorticoid biosynthetic process", "Regulation of glucocorticoid metabolic process", "Regulation of glucocorticoid receptor signaling pathway", "Regulation of glucocorticoid secretion", "Regulation of gluconeogenesis", "Regulation of glucose import", "Regulation of glucose metabolic process", "Regulation of glucose transmembrane transport", "Regulation of glucosylceramidase activity", "Regulation of glutamate receptor clustering", "Regulation of glutamate secretion", "Regulation of glycogen catabolic process", "Regulation of glycogen metabolic process", "Regulation of glycolytic process", "Regulation of glycoprotein metabolic process", "Regulation of golgi organization", "Regulation of golgi to plasma membrane protein transport", "Regulation of gonad development", "Regulation of granulocyte chemotaxis", "Regulation of growth", "Regulation of gtp binding", "Regulation of gtpase activity", "Regulation of guanyl nucleotide exchange factor activity", "Regulation of hair cycle", "Regulation of hair follicle development", "Regulation of heart contraction", "Regulation of heart growth", "Regulation of heart rate", "Regulation of heart rate by cardiac conduction", "Regulation of heart rate by chemical signal", "Regulation of helicase activity", "Regulation of hematopoietic progenitor cell differentiation", "Regulation of hematopoietic stem cell differentiation", "Regulation of hematopoietic stem cell proliferation", "Regulation of hemoglobin biosynthetic process", "Regulation of hemopoiesis", "Regulation of hepatic stellate cell activation", "Regulation of hepatocyte apoptotic process", "Regulation of heterotypic cell cell adhesion", "Regulation of hexokinase activity", "Regulation of high voltage gated calcium channel activity", "Regulation of hippo signaling", "Regulation of histamine secretion by mast cell", "Regulation of histone deacetylation", "Regulation of histone h2b ubiquitination", "Regulation of histone h3 k14 acetylation", "Regulation of histone h3 k27 methylation", "Regulation of histone h3 k4 methylation", "Regulation of histone h3 k9 methylation", "Regulation of histone h3 k9 trimethylation", "Regulation of histone h4 acetylation", "Regulation of histone h4 k16 acetylation", "Regulation of histone methylation", "Regulation of histone modification", "Regulation of histone phosphorylation", "Regulation of histone ubiquitination", "Regulation of homotypic cell cell adhesion", "Regulation of hormone biosynthetic process", "Regulation of hormone levels", "Regulation of hormone metabolic process", "Regulation of hormone secretion", "Regulation of humoral immune response", "Regulation of hyaluronan biosynthetic process", "Regulation of hydrogen peroxide biosynthetic process", "Regulation of hydrogen peroxide mediated programmed cell death", "Regulation of hydrogen peroxide metabolic process", "Regulation of hydrolase activity", "Regulation of i kappab phosphorylation", "Regulation of icosanoid secretion", "Regulation of immune effector process", "Regulation of immune response", "Regulation of immune system process", "Regulation of immunoglobulin production", "Regulation of inclusion body assembly", "Regulation of inflammatory response", "Regulation of inflammatory response to antigenic stimulus", "Regulation of innate immune response", "Regulation of inositol 1 4 5 trisphosphate sensitive calcium release channel activity", "Regulation of insulin like growth factor receptor signaling pathway", "Regulation of insulin receptor signaling pathway", "Regulation of insulin secretion", "Regulation of insulin secretion involved in cellular response to glucose stimulus", "Regulation of integrin activation", "Regulation of integrin mediated signaling pathway", "Regulation of interleukin 1 mediated signaling pathway", "Regulation of intestinal absorption", "Regulation of intracellular estrogen receptor signaling pathway", "Regulation of intracellular lipid transport", "Regulation of intracellular protein transport", "Regulation of intracellular signal transduction", "Regulation of intracellular steroid hormone receptor signaling pathway", "Regulation of intracellular transport", "Regulation of intrinsic apoptotic signaling pathway", "Regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Regulation of inward rectifier potassium channel activity", "Regulation of ion transmembrane transport", "Regulation of ion transport", "Regulation of ire1 mediated unfolded protein response", "Regulation of iron ion transmembrane transport", "Regulation of iron ion transport", "Regulation of isomerase activity", "Regulation of isotype switching", "Regulation of jnk cascade", "Regulation of jun kinase activity", "Regulation of keratinocyte differentiation", "Regulation of keratinocyte migration", "Regulation of keratinocyte proliferation", "Regulation of kidney development", "Regulation of l glutamate import across plasma membrane", "Regulation of lamellipodium assembly", "Regulation of lamellipodium morphogenesis", "Regulation of lamellipodium organization", "Regulation of leukocyte adhesion to vascular endothelial cell", "Regulation of leukocyte apoptotic process", "Regulation of leukocyte chemotaxis", "Regulation of leukocyte degranulation", "Regulation of leukocyte differentiation", "Regulation of leukocyte mediated cytotoxicity", "Regulation of leukocyte mediated immunity", "Regulation of leukocyte migration", "Regulation of leukocyte proliferation", "Regulation of ligase activity", "Regulation of lipase activity", "Regulation of lipid biosynthetic process", "Regulation of lipid catabolic process", "Regulation of lipid kinase activity", "Regulation of lipid localization", "Regulation of lipid metabolic process", "Regulation of lipid storage", "Regulation of lipid transport", "Regulation of lipophagy", "Regulation of lipopolysaccharide mediated signaling pathway", "Regulation of lipoprotein metabolic process", "Regulation of lipoprotein particle clearance", "Regulation of locomotion involved in locomotory behavior", "Regulation of long chain fatty acid import across plasma membrane", "Regulation of long chain fatty acid import into cell", "Regulation of long term neuronal synaptic plasticity", "Regulation of long term synaptic depression", "Regulation of long term synaptic potentiation", "Regulation of low density lipoprotein particle clearance", "Regulation of lyase activity", "Regulation of lymphangiogenesis", "Regulation of lymphocyte activation", "Regulation of lymphocyte apoptotic process", "Regulation of lymphocyte chemotaxis", "Regulation of lymphocyte differentiation", "Regulation of lymphocyte mediated immunity", "Regulation of lymphocyte migration", "Regulation of lymphoid progenitor cell differentiation", "Regulation of lysosomal lumen ph", "Regulation of lysosomal protein catabolic process", "Regulation of lysosome organization", "Regulation of macroautophagy", "Regulation of macrophage activation", "Regulation of macrophage apoptotic process", "Regulation of macrophage chemotaxis", "Regulation of macrophage migration", "Regulation of macrophage proliferation", "Regulation of maintenance of sister chromatid cohesion", "Regulation of male gonad development", "Regulation of mammary gland epithelial cell proliferation", "Regulation of map kinase activity", "Regulation of mast cell activation", "Regulation of mast cell activation involved in immune response", "Regulation of matrix metallopeptidase secretion", "Regulation of mda 5 signaling pathway", "Regulation of megakaryocyte differentiation", "Regulation of meiotic cell cycle", "Regulation of meiotic cell cycle phase transition", "Regulation of meiotic nuclear division", "Regulation of membrane depolarization", "Regulation of membrane depolarization during action potential", "Regulation of membrane depolarization during cardiac muscle cell action potential", "Regulation of membrane lipid distribution", "Regulation of membrane permeability", "Regulation of membrane potential", "Regulation of membrane protein ectodomain proteolysis", "Regulation of membrane repolarization", "Regulation of membrane repolarization during action potential", "Regulation of membrane repolarization during cardiac muscle cell action potential", "Regulation of membrane tubulation", "Regulation of mesenchymal cell proliferation", "Regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis", "Regulation of mesoderm development", "Regulation of metal ion transport", "Regulation of metalloendopeptidase activity", "Regulation of metallopeptidase activity", "Regulation of metanephros development", "Regulation of metaphase plate congression", "Regulation of microglial cell activation", "Regulation of microtubule based movement", "Regulation of microtubule based process", "Regulation of microtubule binding", "Regulation of microtubule cytoskeleton organization", "Regulation of microtubule depolymerization", "Regulation of microtubule nucleation", "Regulation of microtubule polymerization", "Regulation of microtubule polymerization or depolymerization", "Regulation of microvillus assembly", "Regulation of microvillus length", "Regulation of microvillus organization", "Regulation of mirna catabolic process", "Regulation of mirna metabolic process", "Regulation of mirna transcription", "Regulation of mitochondrial atp synthesis coupled electron transport", "Regulation of mitochondrial dna replication", "Regulation of mitochondrial electron transport nadh to ubiquinone", "Regulation of mitochondrial fission", "Regulation of mitochondrial fusion", "Regulation of mitochondrial gene expression", "Regulation of mitochondrial membrane permeability", "Regulation of mitochondrial membrane permeability involved in apoptotic process", "Regulation of mitochondrial membrane potential", "Regulation of mitochondrial mrna stability", "Regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Regulation of mitochondrial rna catabolic process", "Regulation of mitochondrion organization", "Regulation of mitophagy", "Regulation of mitotic cell cycle", "Regulation of mitotic cell cycle phase transition", "Regulation of mitotic cell cycle spindle assembly checkpoint", "Regulation of mitotic centrosome separation", "Regulation of mitotic cytokinesis", "Regulation of mitotic nuclear division", "Regulation of mitotic recombination", "Regulation of mitotic sister chromatid segregation", "Regulation of mitotic spindle assembly", "Regulation of modification of postsynaptic structure", "Regulation of modification of synaptic structure", "Regulation of monocyte chemotaxis", "Regulation of monocyte differentiation", "Regulation of monocyte extravasation", "Regulation of mononuclear cell migration", "Regulation of monooxygenase activity", "Regulation of morphogenesis of a branching structure", "Regulation of morphogenesis of an epithelium", "Regulation of motor neuron apoptotic process", "Regulation of mrna 3 end processing", "Regulation of mrna binding", "Regulation of mrna catabolic process", "Regulation of mrna export from nucleus", "Regulation of mrna metabolic process", "Regulation of mrna polyadenylation", "Regulation of mrna processing", "Regulation of mrna splicing via spliceosome", "Regulation of mucus secretion", "Regulation of multicellular organism growth", "Regulation of multicellular organismal development", "Regulation of muscle adaptation", "Regulation of muscle cell differentiation", "Regulation of muscle contraction", "Regulation of muscle hypertrophy", "Regulation of muscle organ development", "Regulation of muscle system process", "Regulation of myelination", "Regulation of myeloid cell apoptotic process", "Regulation of myeloid cell differentiation", "Regulation of myeloid leukocyte differentiation", "Regulation of myeloid leukocyte mediated immunity", "Regulation of myoblast differentiation", "Regulation of myoblast fusion", "Regulation of myosin light chain phosphatase activity", "Regulation of myotube differentiation", "Regulation of nad p h oxidase activity", "Regulation of nadp metabolic process", "Regulation of natural killer cell activation", "Regulation of natural killer cell mediated immunity", "Regulation of necrotic cell death", "Regulation of nervous system development", "Regulation of nervous system process", "Regulation of neural precursor cell proliferation", "Regulation of neuroblast proliferation", "Regulation of neurogenesis", "Regulation of neuromuscular junction development", "Regulation of neuron differentiation", "Regulation of neuron migration", "Regulation of neuron projection arborization", "Regulation of neuron projection development", "Regulation of neuron projection regeneration", "Regulation of neuronal action potential", "Regulation of neuronal synaptic plasticity", "Regulation of neurotransmitter levels", "Regulation of neurotransmitter receptor activity", "Regulation of neurotransmitter transport", "Regulation of neurotransmitter uptake", "Regulation of neurotrophin trk receptor signaling pathway", "Regulation of neutrophil chemotaxis", "Regulation of neutrophil migration", "Regulation of nik nf kappab signaling", "Regulation of nitric oxide metabolic process", "Regulation of nitric oxide synthase activity", "Regulation of nk t cell activation", "Regulation of nk t cell differentiation", "Regulation of nmda receptor activity", "Regulation of non motile cilium assembly", "Regulation of notch signaling pathway", "Regulation of nuclear cell cycle dna replication", "Regulation of nuclear division", "Regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Regulation of nuclear transcribed mrna poly a tail shortening", "Regulation of nuclease activity", "Regulation of nucleobase containing compound transport", "Regulation of nucleocytoplasmic transport", "Regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Regulation of nucleotide binding oligomerization domain containing signaling pathway", "Regulation of nucleotide biosynthetic process", "Regulation of nucleotide metabolic process", "Regulation of oligodendrocyte differentiation", "Regulation of oocyte maturation", "Regulation of organ growth", "Regulation of organelle assembly", "Regulation of organelle organization", "Regulation of organelle transport along microtubule", "Regulation of organic acid transport", "Regulation of ossification", "Regulation of osteoblast differentiation", "Regulation of osteoblast proliferation", "Regulation of osteoclast differentiation", "Regulation of oxidative phosphorylation", "Regulation of oxidative stress induced cell death", "Regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Regulation of oxidoreductase activity", "Regulation of p38mapk cascade", "Regulation of pattern recognition receptor signaling pathway", "Regulation of penile erection", "Regulation of peptidase activity", "Regulation of peptide transport", "Regulation of peptidyl lysine acetylation", "Regulation of peptidyl serine phosphorylation", "Regulation of peptidyl serine phosphorylation of stat protein", "Regulation of peptidyl threonine phosphorylation", "Regulation of peptidyl tyrosine phosphorylation", "Regulation of perk mediated unfolded protein response", "Regulation of peroxisome proliferator activated receptor signaling pathway", "Regulation of ph", "Regulation of phagocytosis", "Regulation of phenotypic switching", "Regulation of phosphatase activity", "Regulation of phosphatidylcholine biosynthetic process", "Regulation of phosphatidylcholine metabolic process", "Regulation of phosphatidylinositol 3 kinase activity", "Regulation of phosphatidylinositol 3 kinase signaling", "Regulation of phospholipase a2 activity", "Regulation of phospholipase activity", "Regulation of phospholipase c activity", "Regulation of phospholipid biosynthetic process", "Regulation of phospholipid catabolic process", "Regulation of phospholipid metabolic process", "Regulation of phosphoprotein phosphatase activity", "Regulation of phosphorus metabolic process", "Regulation of pigmentation", "Regulation of pinocytosis", "Regulation of plasma lipoprotein particle levels", "Regulation of plasma membrane organization", "Regulation of plasminogen activation", "Regulation of platelet activation", "Regulation of platelet aggregation", "Regulation of platelet derived growth factor receptor signaling pathway", "Regulation of podosome assembly", "Regulation of polysaccharide metabolic process", "Regulation of post translational protein modification", "Regulation of postsynapse organization", "Regulation of postsynaptic membrane neurotransmitter receptor levels", "Regulation of postsynaptic membrane potential", "Regulation of postsynaptic neurotransmitter receptor internalization", "Regulation of potassium ion import", "Regulation of potassium ion transmembrane transporter activity", "Regulation of potassium ion transport", "Regulation of presynapse organization", "Regulation of presynaptic cytosolic calcium ion concentration", "Regulation of pro b cell differentiation", "Regulation of production of molecular mediator of immune response", "Regulation of production of small rna involved in gene silencing by rna", "Regulation of programmed necrotic cell death", "Regulation of prostaglandin secretion", "Regulation of proteasomal protein catabolic process", "Regulation of proteasomal ubiquitin dependent protein catabolic process", "Regulation of protein acetylation", "Regulation of protein adp ribosylation", "Regulation of protein autophosphorylation", "Regulation of protein autoubiquitination", "Regulation of protein binding", "Regulation of protein catabolic process", "Regulation of protein catabolic process in the vacuole", "Regulation of protein complex stability", "Regulation of protein containing complex assembly", "Regulation of protein containing complex disassembly", "Regulation of protein deacetylation", "Regulation of protein dephosphorylation", "Regulation of protein depolymerization", "Regulation of protein deubiquitination", "Regulation of protein exit from endoplasmic reticulum", "Regulation of protein export from nucleus", "Regulation of protein folding", "Regulation of protein glycosylation", "Regulation of protein import", "Regulation of protein k63 linked ubiquitination", "Regulation of protein kinase a signaling", "Regulation of protein kinase activity", "Regulation of protein kinase c signaling", "Regulation of protein lipidation", "Regulation of protein localization", "Regulation of protein localization to cell cortex", "Regulation of protein localization to cell periphery", "Regulation of protein localization to cell surface", "Regulation of protein localization to centrosome", "Regulation of protein localization to chromatin", "Regulation of protein localization to chromosome telomeric region", "Regulation of protein localization to cilium", "Regulation of protein localization to endosome", "Regulation of protein localization to membrane", "Regulation of protein localization to nucleolus", "Regulation of protein localization to nucleus", "Regulation of protein localization to plasma membrane", "Regulation of protein localization to synapse", "Regulation of protein maturation", "Regulation of protein modification by small protein conjugation or removal", "Regulation of protein modification process", "Regulation of protein monoubiquitination", "Regulation of protein neddylation", "Regulation of protein phosphorylation", "Regulation of protein polymerization", "Regulation of protein polyubiquitination", "Regulation of protein secretion", "Regulation of protein serine threonine kinase activity", "Regulation of protein stability", "Regulation of protein sumoylation", "Regulation of protein targeting", "Regulation of protein targeting to membrane", "Regulation of protein tyrosine kinase activity", "Regulation of protein tyrosine phosphatase activity", "Regulation of proteolysis", "Regulation of proton transport", "Regulation of rac protein signal transduction", "Regulation of ras protein signal transduction", "Regulation of reactive oxygen species biosynthetic process", "Regulation of reactive oxygen species metabolic process", "Regulation of receptor binding", "Regulation of receptor catabolic process", "Regulation of receptor clustering", "Regulation of receptor internalization", "Regulation of receptor localization to synapse", "Regulation of receptor mediated endocytosis", "Regulation of receptor mediated endocytosis involved in cholesterol transport", "Regulation of receptor recycling", "Regulation of receptor signaling pathway via stat", "Regulation of regulated secretory pathway", "Regulation of relaxation of muscle", "Regulation of release of cytochrome c from mitochondria", "Regulation of release of sequestered calcium ion into cytosol", "Regulation of removal of superoxide radicals", "Regulation of renal system process", "Regulation of reproductive process", "Regulation of respiratory burst", "Regulation of respiratory gaseous exchange", "Regulation of respiratory gaseous exchange by nervous system process", "Regulation of respiratory system process", "Regulation of response to biotic stimulus", "Regulation of response to cytokine stimulus", "Regulation of response to dna damage stimulus", "Regulation of response to endoplasmic reticulum stress", "Regulation of response to external stimulus", "Regulation of response to extracellular stimulus", "Regulation of response to food", "Regulation of response to interferon gamma", "Regulation of response to osmotic stress", "Regulation of response to oxidative stress", "Regulation of response to reactive oxygen species", "Regulation of response to stress", "Regulation of response to tumor cell", "Regulation of response to wounding", "Regulation of retinoic acid receptor signaling pathway", "Regulation of retrograde protein transport er to cytosol", "Regulation of retrograde transport endosome to golgi", "Regulation of rho dependent protein serine threonine kinase activity", "Regulation of rho protein signal transduction", "Regulation of rhodopsin mediated signaling pathway", "Regulation of ribonuclease activity", "Regulation of ribosome biogenesis", "Regulation of rig i signaling pathway", "Regulation of rna binding", "Regulation of rna export from nucleus", "Regulation of rna polymerase ii regulatory region sequence specific dna binding", "Regulation of rna polymerase ii transcription preinitiation complex assembly", "Regulation of rna splicing", "Regulation of rrna processing", "Regulation of ruffle assembly", "Regulation of ryanodine sensitive calcium release channel activity", "Regulation of secondary heart field cardioblast proliferation", "Regulation of secondary metabolic process", "Regulation of secretion", "Regulation of sensory perception", "Regulation of sequestering of triglyceride", "Regulation of sequestering of zinc ion", "Regulation of short term neuronal synaptic plasticity", "Regulation of signal transduction by p53 class mediator", "Regulation of signaling receptor activity", "Regulation of sister chromatid cohesion", "Regulation of skeletal muscle adaptation", "Regulation of skeletal muscle cell differentiation", "Regulation of skeletal muscle contraction", "Regulation of skeletal muscle contraction by calcium ion signaling", "Regulation of skeletal muscle fiber development", "Regulation of skeletal muscle tissue development", "Regulation of smad protein complex assembly", "Regulation of smad protein signal transduction", "Regulation of small gtpase mediated signal transduction", "Regulation of small molecule metabolic process", "Regulation of smooth muscle cell differentiation", "Regulation of smooth muscle contraction", "Regulation of smoothened signaling pathway", "Regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Regulation of snrna transcription by rna polymerase ii", "Regulation of sodium ion transmembrane transport", "Regulation of sodium ion transport", "Regulation of sodium proton antiporter activity", "Regulation of sphingolipid biosynthetic process", "Regulation of spindle assembly", "Regulation of spindle organization", "Regulation of spontaneous synaptic transmission", "Regulation of sprouting angiogenesis", "Regulation of srebp signaling pathway", "Regulation of stem cell differentiation", "Regulation of stem cell division", "Regulation of stem cell population maintenance", "Regulation of stem cell proliferation", "Regulation of steroid biosynthetic process", "Regulation of steroid hormone biosynthetic process", "Regulation of steroid hormone secretion", "Regulation of steroid metabolic process", "Regulation of sterol transport", "Regulation of store operated calcium channel activity", "Regulation of stress activated protein kinase signaling cascade", "Regulation of stress granule assembly", "Regulation of striated muscle cell differentiation", "Regulation of striated muscle contraction", "Regulation of substrate adhesion dependent cell spreading", "Regulation of sulfur metabolic process", "Regulation of superoxide anion generation", "Regulation of superoxide dismutase activity", "Regulation of superoxide metabolic process", "Regulation of supramolecular fiber organization", "Regulation of synapse assembly", "Regulation of synapse maturation", "Regulation of synapse structural plasticity", "Regulation of synapse structure or activity", "Regulation of synaptic plasticity", "Regulation of synaptic transmission dopaminergic", "Regulation of synaptic transmission gabaergic", "Regulation of synaptic transmission glutamatergic", "Regulation of synaptic vesicle cycle", "Regulation of synaptic vesicle endocytosis", "Regulation of synaptic vesicle exocytosis", "Regulation of synaptic vesicle priming", "Regulation of synaptic vesicle recycling", "Regulation of syncytium formation by plasma membrane fusion", "Regulation of system process", "Regulation of systemic arterial blood pressure", "Regulation of systemic arterial blood pressure by endothelin", "Regulation of systemic arterial blood pressure by hormone", "Regulation of systemic arterial blood pressure by renin angiotensin", "Regulation of systemic arterial blood pressure mediated by a chemical signal", "Regulation of t cell activation", "Regulation of t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell", "Regulation of t cell apoptotic process", "Regulation of t cell chemotaxis", "Regulation of t cell differentiation", "Regulation of t cell differentiation in thymus", "Regulation of t cell mediated cytotoxicity", "Regulation of t cell mediated immune response to tumor cell", "Regulation of t cell mediated immunity", "Regulation of t cell migration", "Regulation of t cell proliferation", "Regulation of t cell receptor signaling pathway", "Regulation of t circle formation", "Regulation of t helper 1 cell differentiation", "Regulation of t helper 1 type immune response", "Regulation of t helper 2 cell differentiation", "Regulation of t helper cell differentiation", "Regulation of tau protein kinase activity", "Regulation of telomerase activity", "Regulation of telomere capping", "Regulation of telomere maintenance", "Regulation of telomere maintenance via telomere lengthening", "Regulation of tetrapyrrole metabolic process", "Regulation of the force of heart contraction", "Regulation of thymocyte apoptotic process", "Regulation of tissue remodeling", "Regulation of tolerance induction", "Regulation of toll like receptor 3 signaling pathway", "Regulation of toll like receptor 4 signaling pathway", "Regulation of toll like receptor 7 signaling pathway", "Regulation of toll like receptor 9 signaling pathway", "Regulation of toll like receptor signaling pathway", "Regulation of tor signaling", "Regulation of torc2 signaling", "Regulation of trail activated apoptotic signaling pathway", "Regulation of trans synaptic signaling", "Regulation of transcription by glucose", "Regulation of transcription by rna polymerase i", "Regulation of transcription by rna polymerase iii", "Regulation of transcription elongation from rna polymerase ii promoter", "Regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Regulation of transcription from rna polymerase ii promoter in response to oxidative stress", "Regulation of transcription involved in g1 s transition of mitotic cell cycle", "Regulation of transcription of nucleolar large rrna by rna polymerase i", "Regulation of transcription regulatory region dna binding", "Regulation of transferase activity", "Regulation of transforming growth factor beta activation", "Regulation of transforming growth factor beta1 production", "Regulation of translation at synapse modulating synaptic transmission", "Regulation of translation in response to endoplasmic reticulum stress", "Regulation of translation in response to stress", "Regulation of translation initiation in response to endoplasmic reticulum stress", "Regulation of translational elongation", "Regulation of translational fidelity", "Regulation of translational initiation", "Regulation of translational initiation by eif2 alpha phosphorylation", "Regulation of translational initiation in response to stress", "Regulation of translational termination", "Regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Regulation of transmembrane transport", "Regulation of transmission of nerve impulse", "Regulation of transport", "Regulation of transporter activity", "Regulation of transposition", "Regulation of triglyceride biosynthetic process", "Regulation of triglyceride metabolic process", "Regulation of tube size", "Regulation of tumor necrosis factor mediated signaling pathway", "Regulation of type b pancreatic cell development", "Regulation of type i interferon mediated signaling pathway", "Regulation of ubiquitin dependent protein catabolic process", "Regulation of ubiquitin protein ligase activity", "Regulation of ubiquitin protein transferase activity", "Regulation of ubiquitin specific protease activity", "Regulation of unsaturated fatty acid biosynthetic process", "Regulation of urine volume", "Regulation of vacuole organization", "Regulation of vascular associated smooth muscle cell differentiation", "Regulation of vascular associated smooth muscle contraction", "Regulation of vascular endothelial growth factor receptor signaling pathway", "Regulation of vascular permeability", "Regulation of vascular wound healing", "Regulation of vasculature development", "Regulation of vasculogenesis", "Regulation of vasoconstriction", "Regulation of ventricular cardiac muscle cell action potential", "Regulation of very low density lipoprotein particle clearance", "Regulation of vesicle fusion", "Regulation of vesicle mediated transport", "Regulation of vesicle size", "Regulation of viral entry into host cell", "Regulation of viral genome replication", "Regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Regulation of viral process", "Regulation of viral transcription", "Regulation of vitamin d receptor signaling pathway", "Regulation of vitamin metabolic process", "Regulation of voltage gated calcium channel activity", "Regulation of water loss via skin", "Regulation of wnt signaling pathway", "Regulation of wound healing", "Regulation of wound healing spreading of epidermal cells", "Regulation of xenophagy", "Regulatory t cell differentiation", "Relaxation of cardiac muscle", "Relaxation of muscle", "Release of cytochrome c from mitochondria", "Release of sequestered calcium ion into cytosol by endoplasmic reticulum", "Renal absorption", "Renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure", "Renal filtration", "Renal sodium excretion", "Renal sodium ion absorption", "Renal sodium ion transport", "Renal system process", "Renal system process involved in regulation of systemic arterial blood pressure", "Renal system vasculature development", "Renal tubular secretion", "Renal tubule development", "Renal vesicle development", "Renal vesicle formation", "Renal water homeostasis", "Replacement ossification", "Replication born double strand break repair via sister chromatid exchange", "Replication fork processing", "Replication fork protection", "Replicative senescence", "Reproduction", "Reproductive behavior", "Reproductive system development", "Rescue of stalled ribosome", "Resolution of meiotic recombination intermediates", "Respiratory burst", "Respiratory burst involved in defense response", "Respiratory burst involved in inflammatory response", "Respiratory chain complex iii assembly", "Respiratory chain complex iv assembly", "Respiratory electron transport chain", "Respiratory gaseous exchange by respiratory system", "Respiratory system development", "Respiratory system process", "Response to abiotic stimulus", "Response to acetylcholine", "Response to acid chemical", "Response to acidic ph", "Response to actinomycin d", "Response to activity", "Response to alcohol", "Response to aldosterone", "Response to alkaloid", "Response to amine", "Response to amino acid starvation", "Response to ammonium ion", "Response to amphetamine", "Response to amyloid beta", "Response to angiotensin", "Response to antibiotic", "Response to arsenic containing substance", "Response to arsenite ion", "Response to atp", "Response to auditory stimulus", "Response to axon injury", "Response to bacterium", "Response to bmp", "Response to cadmium ion", "Response to caffeine", "Response to calcium ion", "Response to camp", "Response to camptothecin", "Response to carbohydrate", "Response to catecholamine", "Response to cell cycle checkpoint signaling", "Response to cgmp", "Response to chemokine", "Response to cholesterol", "Response to cisplatin", "Response to cobalt ion", "Response to cocaine", "Response to cold", "Response to copper ion", "Response to corticosteroid", "Response to corticosterone", "Response to cytokine", "Response to dexamethasone", "Response to dietary excess", "Response to dopamine", "Response to dsrna", "Response to electrical stimulus", "Response to endogenous stimulus", "Response to endoplasmic reticulum stress", "Response to epidermal growth factor", "Response to epinephrine", "Response to estradiol", "Response to estrogen", "Response to ethanol", "Response to ether", "Response to extracellular stimulus", "Response to fatty acid", "Response to fibroblast growth factor", "Response to fluid shear stress", "Response to folic acid", "Response to follicle stimulating hormone", "Response to food", "Response to forskolin", "Response to fungus", "Response to gamma radiation", "Response to glucagon", "Response to glycoside", "Response to gonadotropin", "Response to granulocyte macrophage colony stimulating factor", "Response to growth factor", "Response to growth hormone", "Response to heat", "Response to hepatocyte growth factor", "Response to histamine", "Response to hormone", "Response to human chorionic gonadotropin", "Response to hydrogen peroxide", "Response to hydroperoxide", "Response to hydrostatic pressure", "Response to hydroxyurea", "Response to hyperoxia", "Response to immobilization stress", "Response to increased oxygen levels", "Response to indole 3 methanol", "Response to inorganic substance", "Response to insecticide", "Response to insulin", "Response to interferon alpha", "Response to interferon beta", "Response to interferon gamma", "Response to interleukin 1", "Response to interleukin 12", "Response to interleukin 18", "Response to interleukin 4", "Response to interleukin 6", "Response to interleukin 7", "Response to ionizing radiation", "Response to iron ion", "Response to ischemia", "Response to isoquinoline alkaloid", "Response to ketone", "Response to l ascorbic acid", "Response to l glutamate", "Response to l phenylalanine derivative", "Response to lead ion", "Response to lectin", "Response to leptin", "Response to leucine", "Response to leukemia inhibitory factor", "Response to light intensity", "Response to light stimulus", "Response to lipid", "Response to lipoteichoic acid", "Response to lithium ion", "Response to magnesium ion", "Response to manganese ion", "Response to mechanical stimulus", "Response to mercury ion", "Response to metal ion", "Response to methylmercury", "Response to mineralocorticoid", "Response to misfolded protein", "Response to mitochondrial depolarisation", "Response to molecule of bacterial origin", "Response to monosaccharide", "Response to muramyl dipeptide", "Response to muscle activity", "Response to muscle stretch", "Response to nerve growth factor", "Response to nicotine", "Response to nitric oxide", "Response to nitrogen compound", "Response to nitrosative stress", "Response to nutrient", "Response to oleic acid", "Response to organic cyclic compound", "Response to osmotic stress", "Response to oxidative stress", "Response to oxygen containing compound", "Response to oxygen glucose deprivation", "Response to oxygen levels", "Response to oxygen radical", "Response to pain", "Response to parathyroid hormone", "Response to peptide", "Response to peptide hormone", "Response to peptidoglycan", "Response to ph", "Response to phorbol 13 acetate 12 myristate", "Response to platelet derived growth factor", "Response to potassium ion", "Response to progesterone", "Response to prostaglandin", "Response to prostaglandin e", "Response to purine containing compound", "Response to radiation", "Response to reactive oxygen species", "Response to redox state", "Response to retinoic acid", "Response to salt", "Response to salt stress", "Response to selenium ion", "Response to sodium arsenite", "Response to sorbitol", "Response to starvation", "Response to staurosporine", "Response to steroid hormone", "Response to sterol", "Response to sterol depletion", "Response to temperature stimulus", "Response to testosterone", "Response to thyroglobulin triiodothyronine", "Response to thyroid hormone", "Response to thyroxine", "Response to topologically incorrect protein", "Response to toxic substance", "Response to transforming growth factor beta", "Response to tumor cell", "Response to tumor necrosis factor", "Response to type i interferon", "Response to uv", "Response to uv a", "Response to uv b", "Response to uv c", "Response to virus", "Response to vitamin", "Response to vitamin a", "Response to vitamin d", "Response to vitamin e", "Response to vitamin k", "Response to water", "Response to wounding", "Response to x ray", "Response to xenobiotic stimulus", "Response to yeast", "Response to zinc ion", "Reticulophagy", "Retina development in camera type eye", "Retina homeostasis", "Retina layer formation", "Retina morphogenesis in camera type eye", "Retina vasculature development in camera type eye", "Retina vasculature morphogenesis in camera type eye", "Retinal cell apoptotic process", "Retinal cell programmed cell death", "Retinal cone cell differentiation", "Retinal ganglion cell axon guidance", "Retinal metabolic process", "Retinal rod cell development", "Retinal rod cell differentiation", "Retinoic acid metabolic process", "Retinoic acid receptor signaling pathway", "Retinol metabolic process", "Retrograde axonal transport", "Retrograde trans synaptic signaling", "Retrograde trans synaptic signaling by lipid", "Retrograde transport endosome to golgi", "Retrograde transport vesicle recycling within golgi", "Retrograde vesicle mediated transport golgi to endoplasmic reticulum", "Reverse cholesterol transport", "Reversible differentiation", "Rho protein signal transduction", "Rhodopsin mediated signaling pathway", "Rhythmic behavior", "Rhythmic process", "Ribonucleoprotein complex biogenesis", "Ribonucleoprotein complex disassembly", "Ribonucleoprotein complex localization", "Ribonucleoprotein complex subunit organization", "Ribonucleoside catabolic process", "Ribonucleoside diphosphate biosynthetic process", "Ribonucleoside diphosphate catabolic process", "Ribonucleoside diphosphate metabolic process", "Ribonucleoside metabolic process", "Ribonucleoside monophosphate biosynthetic process", "Ribonucleoside monophosphate catabolic process", "Ribonucleoside monophosphate metabolic process", "Ribonucleoside triphosphate biosynthetic process", "Ribonucleoside triphosphate metabolic process", "Ribonucleotide catabolic process", "Ribose phosphate biosynthetic process", "Ribose phosphate metabolic process", "Ribosomal large subunit assembly", "Ribosomal large subunit biogenesis", "Ribosomal large subunit export from nucleus", "Ribosomal small subunit assembly", "Ribosomal small subunit biogenesis", "Ribosomal small subunit export from nucleus", "Ribosomal subunit export from nucleus", "Ribosome assembly", "Ribosome associated ubiquitin dependent protein catabolic process", "Ribosome biogenesis", "Ribosome disassembly", "Rig i signaling pathway", "Righting reflex", "Rna 3 end processing", "Rna 3 uridylation", "Rna 5 end processing", "Rna capping", "Rna catabolic process", "Rna decapping", "Rna dependent dna biosynthetic process", "Rna destabilization", "Rna export from nucleus", "Rna guanine n7 methylation", "Rna import into mitochondrion", "Rna interference", "Rna localization", "Rna mediated gene silencing by inhibition of translation", "Rna methylation", "Rna modification", "Rna phosphodiester bond hydrolysis", "Rna phosphodiester bond hydrolysis endonucleolytic", "Rna phosphodiester bond hydrolysis exonucleolytic", "Rna polyadenylation", "Rna polymerase i preinitiation complex assembly", "Rna polymerase ii preinitiation complex assembly", "Rna processing", "Rna secondary structure unwinding", "Rna splicing", "Rna splicing via endonucleolytic cleavage and ligation", "Rna splicing via transesterification reactions", "Rna stabilization", "Rna surveillance", "Roof of mouth development", "Roundabout signaling pathway", "Rrna 3 end processing", "Rrna 5 end processing", "Rrna base methylation", "Rrna catabolic process", "Rrna metabolic process", "Rrna methylation", "Rrna modification", "Rrna pseudouridine synthesis", "Rrna transcription", "Rrna transport", "Ruffle assembly", "Ruffle organization", "S adenosylmethionine cycle", "S adenosylmethionine metabolic process", "Salivary gland development", "Sarcomere organization", "Sarcoplasmic reticulum calcium ion transport", "Satellite cell activation involved in skeletal muscle regeneration", "Scarna localization to cajal body", "Scf dependent proteasomal ubiquitin dependent protein catabolic process", "Schwann cell development", "Schwann cell differentiation", "Schwann cell proliferation", "Second messenger mediated signaling", "Secondary alcohol metabolic process", "Secondary metabolic process", "Secondary metabolite biosynthetic process", "Secretion", "Secretion by tissue", "Secretion of lysosomal enzymes", "Secretory granule localization", "Secretory granule organization", "Segment specification", "Segmentation", "Selective autophagy", "Self proteolysis", "Semaphorin plexin signaling pathway", "Semaphorin plexin signaling pathway involved in neuron projection guidance", "Semi lunar valve development", "Seminiferous tubule development", "Sensory organ development", "Sensory organ morphogenesis", "Sensory perception", "Sensory perception of light stimulus", "Sensory perception of mechanical stimulus", "Sensory perception of pain", "Sensory system development", "Septum primum development", "Sequestering of actin monomers", "Sequestering of calcium ion", "Sequestering of iron ion", "Sequestering of metal ion", "Sequestering of triglyceride", "Sequestering of zinc ion", "Serine family amino acid biosynthetic process", "Serine family amino acid catabolic process", "Serine family amino acid metabolic process", "Serine phosphorylation of stat protein", "Serine transport", "Serotonin metabolic process", "Sertoli cell development", "Sertoli cell differentiation", "Sex determination", "Sex differentiation", "Short chain fatty acid catabolic process", "Short chain fatty acid metabolic process", "Short term memory", "Signal complex assembly", "Signal peptide processing", "Signal release", "Signal transduction by p53 class mediator", "Signal transduction in absence of ligand", "Signal transduction in response to dna damage", "Signal transduction involved in regulation of gene expression", "Signaling receptor ligand precursor processing", "Single fertilization", "Single strand break repair", "Single stranded viral rna replication via double stranded dna intermediate", "Sister chromatid cohesion", "Sister chromatid segregation", "Skeletal muscle acetylcholine gated channel clustering", "Skeletal muscle adaptation", "Skeletal muscle cell differentiation", "Skeletal muscle cell proliferation", "Skeletal muscle contraction", "Skeletal muscle fiber differentiation", "Skeletal muscle organ development", "Skeletal muscle satellite cell activation", "Skeletal muscle tissue regeneration", "Skeletal myofibril assembly", "Skeletal system development", "Skeletal system morphogenesis", "Skin development", "Skin epidermis development", "Skin morphogenesis", "Sleep", "Smad protein complex assembly", "Smad protein signal transduction", "Small gtpase mediated signal transduction", "Small molecule biosynthetic process", "Small molecule catabolic process", "Small molecule metabolic process", "Small nucleolar ribonucleoprotein complex assembly", "Small rna loading onto risc", "Smooth muscle adaptation", "Smooth muscle cell apoptotic process", "Smooth muscle cell differentiation", "Smooth muscle cell migration", "Smooth muscle cell proliferation", "Smooth muscle contraction", "Smooth muscle tissue development", "Smoothened signaling pathway", "Smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Snare complex assembly", "Sno s rna metabolic process", "Sno s rna processing", "Snorna localization", "Snrna metabolic process", "Snrna modification", "Snrna processing", "Snrna transcription", "Snrna transcription by rna polymerase ii", "Snrna transport", "Sodium independent organic anion transport", "Sodium ion export across plasma membrane", "Sodium ion homeostasis", "Sodium ion import across plasma membrane", "Sodium ion transmembrane transport", "Sodium ion transport", "Somatic diversification of immune receptors", "Somatic diversification of immune receptors via somatic mutation", "Somatic diversification of immunoglobulins", "Somatic diversification of immunoglobulins involved in immune response", "Somatic diversification of t cell receptor genes", "Somite development", "Somite rostral caudal axis specification", "Somitogenesis", "Specification of animal organ identity", "Specification of symmetry", "Sperm capacitation", "Sperm dna condensation", "Sperm egg recognition", "Sperm motility", "Spermatid differentiation", "Spermatid nucleus differentiation", "Spermatogenesis exchange of chromosomal proteins", "Spermidine metabolic process", "Spermine metabolic process", "Sphingoid metabolic process", "Sphingolipid biosynthetic process", "Sphingolipid mediated signaling pathway", "Sphingolipid metabolic process", "Sphingolipid translocation", "Sphingomyelin biosynthetic process", "Sphingomyelin catabolic process", "Sphingomyelin metabolic process", "Sphingosine biosynthetic process", "Spinal cord development", "Spinal cord motor neuron differentiation", "Spindle assembly", "Spindle elongation", "Spindle localization", "Spindle midzone assembly", "Spindle organization", "Spleen development", "Spliceosomal complex assembly", "Spliceosomal conformational changes to generate catalytic conformation", "Spliceosomal snrnp assembly", "Spliceosomal tri snrnp complex assembly", "Spontaneous synaptic transmission", "Sprouting angiogenesis", "Srp dependent cotranslational protein targeting to membrane", "Srp dependent cotranslational protein targeting to membrane signal sequence recognition", "Srp dependent cotranslational protein targeting to membrane translocation", "Startle response", "Stem cell differentiation", "Stem cell division", "Stem cell proliferation", "Steroid biosynthetic process", "Steroid catabolic process", "Steroid esterification", "Steroid hormone biosynthetic process", "Steroid hormone mediated signaling pathway", "Steroid hormone secretion", "Steroid metabolic process", "Sterol biosynthetic process", "Sterol homeostasis", "Sterol import", "Sterol metabolic process", "Sterol transport", "Store operated calcium entry", "Stress activated protein kinase signaling cascade", "Stress fiber assembly", "Stress granule assembly", "Stress granule disassembly", "Stress induced premature senescence", "Stress response to metal ion", "Striated muscle adaptation", "Striated muscle cell apoptotic process", "Striated muscle cell development", "Striated muscle cell differentiation", "Striated muscle cell proliferation", "Striated muscle contraction", "Striatum development", "Subpallium development", "Substantia nigra development", "Substrate adhesion dependent cell spreading", "Substrate dependent cell migration", "Substrate dependent cell migration cell extension", "Subtelomeric heterochromatin assembly", "Succinate metabolic process", "Succinate transmembrane transport", "Succinyl coa metabolic process", "Suckling behavior", "Sugar mediated signaling pathway", "Sulfate transport", "Sulfation", "Sulfur amino acid biosynthetic process", "Sulfur amino acid catabolic process", "Sulfur amino acid metabolic process", "Sulfur compound biosynthetic process", "Sulfur compound catabolic process", "Sulfur compound metabolic process", "Sulfur compound transport", "Superoxide anion generation", "Superoxide metabolic process", "Suppression of viral release by host", "Supramolecular fiber organization", "Sympathetic ganglion development", "Sympathetic nervous system development", "Synapse assembly", "Synapse maturation", "Synapse organization", "Synaptic membrane adhesion", "Synaptic signaling", "Synaptic transmission dopaminergic", "Synaptic transmission gabaergic", "Synaptic transmission glutamatergic", "Synaptic vesicle budding", "Synaptic vesicle clustering", "Synaptic vesicle cytoskeletal transport", "Synaptic vesicle docking", "Synaptic vesicle endosomal processing", "Synaptic vesicle exocytosis", "Synaptic vesicle localization", "Synaptic vesicle maturation", "Synaptic vesicle membrane organization", "Synaptic vesicle priming", "Synaptic vesicle recycling", "Synaptic vesicle recycling via endosome", "Synaptic vesicle transport", "Synaptic vesicle uncoating", "Synaptonemal complex organization", "Syncytium formation", "T cell activation", "T cell activation involved in immune response", "T cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell", "T cell apoptotic process", "T cell chemotaxis", "T cell cytokine production", "T cell differentiation", "T cell differentiation in thymus", "T cell differentiation involved in immune response", "T cell extravasation", "T cell homeostasis", "T cell lineage commitment", "T cell mediated cytotoxicity", "T cell mediated immune response to tumor cell", "T cell mediated immunity", "T cell migration", "T cell proliferation", "T cell proliferation involved in immune response", "T cell receptor signaling pathway", "T cell selection", "T cell tolerance induction", "T helper 1 cell differentiation", "T helper 1 type immune response", "T helper 17 cell differentiation", "T helper 17 cell lineage commitment", "T helper 17 type immune response", "T helper 2 cell cytokine production", "T helper 2 cell differentiation", "T helper cell lineage commitment", "T tubule organization", "Tail anchored membrane protein insertion into er membrane", "Tangential migration from the subventricular zone to the olfactory bulb", "Taxis", "Telencephalon development", "Telencephalon glial cell migration", "Telencephalon regionalization", "Telomerase holoenzyme complex assembly", "Telomerase rna localization", "Telomere capping", "Telomere maintenance", "Telomere maintenance in response to dna damage", "Telomere maintenance via recombination", "Telomere maintenance via semi conservative replication", "Telomere maintenance via telomere lengthening", "Telomere organization", "Telomeric d loop disassembly", "Telomeric loop disassembly", "Temperature homeostasis", "Terminal button organization", "Terpenoid biosynthetic process", "Terpenoid metabolic process", "Tertiary alcohol metabolic process", "Tetrahydrobiopterin metabolic process", "Tetrahydrofolate biosynthetic process", "Tetrahydrofolate interconversion", "Tetrahydrofolate metabolic process", "Tetrapyrrole biosynthetic process", "Tetrapyrrole catabolic process", "Tetrapyrrole metabolic process", "Thalamus development", "Thiamine containing compound metabolic process", "Thiamine transport", "Thioester biosynthetic process", "Thioester metabolic process", "Thorax and anterior abdomen determination", "Threonine catabolic process", "Threonine metabolic process", "Thrombin activated receptor signaling pathway", "Thrombopoietin mediated signaling pathway", "Thymocyte apoptotic process", "Thymus development", "Thyroid gland development", "Thyroid hormone generation", "Thyroid hormone mediated signaling pathway", "Thyroid hormone metabolic process", "Tight junction organization", "Tissue development", "Tissue migration", "Tissue morphogenesis", "Tissue regeneration", "Tissue remodeling", "Tolerance induction", "Toll like receptor 3 signaling pathway", "Toll like receptor 4 signaling pathway", "Toll like receptor 7 signaling pathway", "Toll like receptor 8 signaling pathway", "Toll like receptor 9 signaling pathway", "Toll like receptor signaling pathway", "Tongue development", "Tongue morphogenesis", "Tor signaling", "Torc1 signaling", "Torc2 signaling", "Toxin metabolic process", "Toxin transport", "Trabecula formation", "Trabecula morphogenesis", "Trachea development", "Trachea formation", "Trachea morphogenesis", "Trail activated apoptotic signaling pathway", "Trans synaptic signaling by lipid", "Trans synaptic signaling by trans synaptic complex", "Trans synaptic signaling modulating synaptic transmission", "Transcription by rna polymerase i", "Transcription by rna polymerase iii", "Transcription coupled nucleotide excision repair", "Transcription dependent tethering of rna polymerase ii gene dna at nuclear periphery", "Transcription elongation from rna polymerase i promoter", "Transcription elongation from rna polymerase ii promoter", "Transcription initiation from rna polymerase i promoter", "Transcription initiation from rna polymerase ii promoter", "Transcription initiation from rna polymerase iii promoter", "Transcription preinitiation complex assembly", "Transcytosis", "Transepithelial chloride transport", "Transepithelial transport", "Transferrin transport", "Transforming growth factor beta activation", "Transforming growth factor beta production", "Transforming growth factor beta receptor signaling pathway", "Transforming growth factor beta1 production", "Transition between fast and slow fiber", "Transition metal ion homeostasis", "Transition metal ion transport", "Translational elongation", "Translational initiation", "Translational readthrough", "Translational termination", "Translesion synthesis", "Translocation of molecules into host", "Transmembrane receptor protein serine threonine kinase signaling pathway", "Transmembrane receptor protein tyrosine kinase signaling pathway", "Transmembrane transport", "Transmission of nerve impulse", "Transport along microtubule", "Transport of virus", "Transposition", "Transposition rna mediated", "Tricarboxylic acid cycle", "Tricarboxylic acid metabolic process", "Triglyceride biosynthetic process", "Triglyceride metabolic process", "Tripartite regional subdivision", "Tripeptide transmembrane transport", "Tripeptide transport", "Trivalent inorganic anion homeostasis", "Trna 3 end processing", "Trna 5 end processing", "Trna 5 leader removal", "Trna aminoacylation for mitochondrial protein translation", "Trna catabolic process", "Trna metabolic process", "Trna methylation", "Trna modification", "Trna processing", "Trna pseudouridine synthesis", "Trna threonylcarbamoyladenosine metabolic process", "Trna transcription", "Trna transport", "Trna wobble base modification", "Trna wobble uridine modification", "Trophectodermal cell differentiation", "Trophoblast cell migration", "Trophoblast giant cell differentiation", "Tryptophan transport", "Tube development", "Tube formation", "Tube morphogenesis", "Tubulin complex assembly", "Tubulin deacetylation", "Tumor necrosis factor mediated signaling pathway", "Tumor necrosis factor superfamily cytokine production", "Type 2 immune response", "Type b pancreatic cell apoptotic process", "Type b pancreatic cell development", "Type i interferon production", "Type i pneumocyte differentiation", "Tyrosine catabolic process", "Tyrosine metabolic process", "Tyrosine phosphorylation of stat protein", "U4 snrna 3 end processing", "Ubiquinone metabolic process", "Ubiquitin dependent endocytosis", "Ubiquitin dependent erad pathway", "Ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin dependent smad protein catabolic process", "Ubiquitin independent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin recycling", "Udp glucose metabolic process", "Udp n acetylglucosamine biosynthetic process", "Udp n acetylglucosamine metabolic process", "Ump biosynthetic process", "Unsaturated fatty acid biosynthetic process", "Unsaturated fatty acid metabolic process", "Urate metabolic process", "Urate transport", "Urea cycle", "Urea metabolic process", "Ureter development", "Ureter morphogenesis", "Ureteric bud elongation", "Urogenital system development", "Uronic acid metabolic process", "Utp biosynthetic process", "Utp metabolic process", "Uv damage excision repair", "Uv protection", "V d j recombination", "Vacuolar acidification", "Vacuolar localization", "Vacuolar proton transporting v type atpase complex assembly", "Vacuolar transport", "Vacuole organization", "Vagina development", "Valine metabolic process", "Vascular associated smooth muscle cell apoptotic process", "Vascular associated smooth muscle cell differentiation", "Vascular associated smooth muscle cell migration", "Vascular associated smooth muscle cell proliferation", "Vascular associated smooth muscle contraction", "Vascular endothelial cell proliferation", "Vascular endothelial growth factor production", "Vascular endothelial growth factor receptor 2 signaling pathway", "Vascular endothelial growth factor receptor signaling pathway", "Vascular endothelial growth factor signaling pathway", "Vascular process in circulatory system", "Vascular transport", "Vascular wound healing", "Vasculature development", "Vasculogenesis", "Vasoconstriction", "Vasodilation", "Ventral spinal cord development", "Ventricular cardiac muscle cell action potential", "Ventricular cardiac muscle cell development", "Ventricular cardiac muscle cell differentiation", "Ventricular cardiac muscle cell membrane repolarization", "Ventricular cardiac muscle tissue development", "Ventricular cardiac muscle tissue morphogenesis", "Ventricular compact myocardium morphogenesis", "Ventricular septum development", "Ventricular septum morphogenesis", "Ventricular system development", "Very long chain fatty acid catabolic process", "Very long chain fatty acid metabolic process", "Very low density lipoprotein particle assembly", "Very low density lipoprotein particle clearance", "Vesicle budding from membrane", "Vesicle cargo loading", "Vesicle cytoskeletal trafficking", "Vesicle docking", "Vesicle docking involved in exocytosis", "Vesicle fusion to plasma membrane", "Vesicle fusion with golgi apparatus", "Vesicle localization", "Vesicle mediated cholesterol transport", "Vesicle mediated transport", "Vesicle mediated transport between endosomal compartments", "Vesicle mediated transport in synapse", "Vesicle mediated transport to the plasma membrane", "Vesicle organization", "Vesicle targeting", "Vesicle targeting rough er to cis golgi", "Vesicle targeting to from or within golgi", "Vesicle tethering", "Vesicle tethering to golgi", "Vesicle transport along microtubule", "Vesicle uncoating", "Viral budding", "Viral gene expression", "Viral genome replication", "Viral life cycle", "Viral process", "Viral protein processing", "Viral release from host cell", "Viral rna genome replication", "Viral transcription", "Viral translation", "Viral translational termination reinitiation", "Virion assembly", "Virion attachment to host cell", "Visual behavior", "Vitamin a metabolic process", "Vitamin b6 metabolic process", "Vitamin biosynthetic process", "Vitamin catabolic process", "Vitamin d metabolic process", "Vitamin d receptor signaling pathway", "Vitamin k metabolic process", "Vitamin metabolic process", "Vitamin transmembrane transport", "Vitamin transport", "Vocalization behavior", "Voluntary musculoskeletal movement", "Walking behavior", "Water homeostasis", "Water soluble vitamin biosynthetic process", "Water soluble vitamin metabolic process", "Water transport", "White fat cell differentiation", "Wnt protein secretion", "Wnt signaling pathway involved in heart development", "Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation", "Wound healing", "Wound healing involved in inflammatory response", "Wound healing spreading of epidermal cells", "Xenobiotic catabolic process", "Xenobiotic export", "Xenobiotic metabolic process", "Xenobiotic transmembrane transport", "Xenobiotic transport", "Xenobiotic transport across blood brain barrier", "Xenophagy", "Xmp metabolic process", "Zinc ion homeostasis", "Zinc ion transport", "Zygotic determination of anterior posterior axis embryo", "Zymogen activation", "Zymogen inhibition"], "available_proteins": ["AAAS", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAP2", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP17A", "AKAP8", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT1S1", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALKBH5", "ALYREF", "AMOT", "ANAPC16", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP3B1", "AP3D1", "AP3M1", "APEH", "APEX1", "API5", "APOL2", "APOOL", "APRT", "AQR", "ARCN1", "ARF4", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL6IP4", "ARL6IP5", "ARL8B", "ARMC1", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "AS3MT", "ASAH1", "ASCC2", "ASCC3", "ASNA1", "ASNS", "ASPH", "ASPM", "ASRGL1", "ATAD1", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATG4B", "ATIC", "ATL2", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7B", "ATPAF1", "ATPIF1", "ATRX", "ATXN10", "ATXN2L", "AUP1", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAK1", "BANF1", "BAP18", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BCAP31", "BCAS2", "BCAT2", "BCCIP", "BCL10", "BCL2L12", "BCL2L13", "BCLAF1", "BCS1L", "BET1", "BIRC6", "BLMH", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOP1", "BPNT1", "BRD2", "BRIX1", "BSG", "BTF3", "BUB3", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C12orf73", "C19orf70", "C1QBP", "C20orf27", "C21orf59", "C2CD5", "C2orf49", "CAB39", "CACUL1", "CACYBP", "CAD", "CALD1", "CALR", "CAND1", "CANX", "CAP1", "CAPN1", "CAPRIN1", "CAPZA1", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP2", "CASP3", "CASP6", "CAST", "CBFB", "CBR1", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC124", "CCDC47", "CCDC6", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD276", "CD2AP", "CD2BP2", "CD47", "CD81", "CDC123", "CDC23", "CDC27", "CDC37", "CDC42", "CDC45", "CDC5L", "CDC73", "CDCA8", "CDK1", "CDK13", "CDK2", "CDK4", "CDK5RAP3", "CDK6", "CDKAL1", "CDKN2A", "CDKN2AIP", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPV", "CEP44", "CEP55", "CERS2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP2A", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHUK", "CIAPIN1", "CIRBP", "CISD2", "CIZ1", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP2", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLP1", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTA", "CLTC", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNOT1", "CNOT11", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COASY", "COG7", "COIL", "COL4A3BP", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "CORO1C", "COTL1", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZL1", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWC22", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DCAF13", "DCAF7", "DCAKD", "DCD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTPP1", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX27", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX5", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEK", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHFR", "DHPS", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIP2B", "DIS3", "DIS3L2", "DKC1", "DLAT", "DLD", "DLST", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC3", "DNAJC7", "DNAJC9", "DNM1", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOHH", "DPF2", "DPH2", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DRG1", "DRG2", "DSG2", "DSP", "DST", "DSTN", "DTL", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EHD1", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENDOD1", "ENO1", "ENOPH1", "ENSA", "ENY2", "EPB41", "EPB41L2", "EPB41L3", "EPHX1", "EPHX2", "EPPK1", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERC1", "ERCC2", "ERCC6L", "ERGIC3", "ERH", "ERI1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EXD2", "EXO1", "EXOC2", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EYA3", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAH", "FAM120B", "FAM162A", "FAM208A", "FAM3C", "FAM49B", "FAM8A1", "FAM91A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FBL", "FBXO22", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FLCN", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNDC3A", "FNTA", "FNTB", "FOXC1", "FOXRED1", "FRG1", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLM", "GCN1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GHITM", "GIGYF2", "GINS1", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLRX3", "GLRX5", "GLS", "GLTP", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPB", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GNS", "GOLGA3", "GOLGB1", "GOPC", "GOT1", "GOT2", "GPAA1", "GPATCH4", "GPD2", "GPI", "GPKOW", "GPR107", "GPR108", "GPS1", "GPT2", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2E1", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP4", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS4", "HAUS5", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEBP1", "HECTD1", "HELLS", "HELZ", "HERC2", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HP1BP3", "HPRT1", "HPS6", "HS1BP3", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "ILF2", "ILF3", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPAD1", "IMPDH2", "INA", "INCENP", "INF2", "INTS3", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IRF2BPL", "IRS4", "ISCU", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPK1", "IVD", "JUP", "KARS", "KAT7", "KCTD12", "KCTD5", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM3B", "KDSR", "KHDRBS1", "KHSRP", "KIAA0368", "KIF11", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KLC1", "KLC2", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LAMP1", "LAMTOR1", "LAMTOR2", "LANCL1", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDAH", "LDHA", "LDHB", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMNA", "LMNB1", "LNPEP", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC40", "LRRC47", "LRRC59", "LRWD1", "LSG1", "LSM14A", "LSM14B", "LSM2", "LSM6", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LZTFL1", "LZTS2", "M6PR", "MACF1", "MAGED2", "MAK16", "MANF", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MCAT", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED17", "MED24", "MED25", "MEPCE", "MESD", "METTL1", "METTL13", "MFF", "MFN2", "MFSD10", "MFSD5", "MGEA5", "MGST2", "MGST3", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MIPEP", "MKI67", "MLEC", "MMAB", "MMGT1", "MMS19", "MOGS", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP2", "MPP6", "MPRIP", "MPST", "MPV17L2", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL19", "MRPL2", "MRPL28", "MRPL3", "MRPL37", "MRPL44", "MRPL58", "MRPL9", "MRPS15", "MRPS17", "MRPS2", "MRPS27", "MRPS28", "MRPS30", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTX1", "MTX2", "MTX3", "MUT", "MVD", "MVK", "MYBBP1A", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA25", "NAA35", "NAA40", "NAA50", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCAPH2", "NCBP1", "NCDN", "NCK1", "NCKAP1", "NCL", "NCLN", "NCOA5", "NCSTN", "NDC1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4", "NEFL", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NFS1", "NHP2", "NIFK", "NIP7", "NIPA2", "NIPSNAP2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NME1", "NME2", "NMT1", "NNT", "NOC2L", "NOC3L", "NOC4L", "NOL11", "NOL6", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOSIP", "NOVA2", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NSA2", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSMCE2", "NSUN2", "NSUN5", "NSUN6", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDT1", "NUDT12", "NUDT16L1", "NUDT21", "NUDT5", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC3", "OSBP", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OTULIN", "OXA1L", "OXSR1", "P3H1", "P4HA1", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAK1IP1", "PAK2", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PASK", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDS5A", "PDS5B", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF2", "PHF5A", "PHF6", "PHGDH", "PHIP", "PI4K2A", "PICALM", "PIGK", "PIGS", "PIGU", "PIH1D1", "PIK3C2A", "PIN1", "PIN4", "PINX1", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN2", "PLA2G15", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PMVK", "PNN", "PNP", "PNPLA6", "PNPLA8", "PNPO", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2G", "POLR2L", "POLR3A", "POLRMT", "PON2", "POP1", "POR", "PPA2", "PPAN", "PPAT", "PPHLN1", "PPIB", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R1", "PPP5C", "PPT1", "PPT2", "PQBP1", "PRAF2", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF39", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTRH2", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXN", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB21", "RAB24", "RAB34", "RAB35", "RAB39A", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB8B", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD51AP1", "RAE1", "RAI14", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP1GDS1", "RAPGEF2", "RARS", "RASA1", "RAVER1", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM39", "RBM4", "RBM8A", "RBMX", "RBMXL1", "RBP1", "RCC1", "RCC2", "RCL1", "RCN1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "REEP5", "RER1", "RETREG3", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFLNB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RINT1", "RMDN1", "RMDN3", "RNASEH2A", "RNASEH2B", "RNASET2", "RNF114", "RNF14", "RNF40", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSBN1", "RSF1", "RSL1D1", "RSU1", "RTCB", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMHD1", "SAMM50", "SAP18", "SAP30BP", "SAR1A", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDCBP", "SDE2", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC63", "SEH1L", "SEL1L", "SENP3", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD7", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN4", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIN3A", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC30A5", "SLC35A4", "SLC35B2", "SLC35F2", "SLC3A2", "SLC9A3R1", "SLFN11", "SLIRP", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SMYD3", "SMYD5", "SNAP23", "SNAP29", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SOAT1", "SOD2", "SON", "SORD", "SPAG9", "SPART", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPECC1L", "SPEN", "SPOUT1", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSRP1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD3NL", "STAT1", "STAT3", "STAU1", "STIM2", "STIP1", "STK4", "STMN1", "STOML2", "STRAP", "STRBP", "STRN", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX17", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SULT2A1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACC3", "TACO1", "TAF15", "TAGLN2", "TALDO1", "TAMM41", "TARDBP", "TARS", "TARS2", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF25", "TCOF1", "TCP1", "TDP2", "TDRKH", "TECR", "TELO2", "TERF2IP", "TES", "TEX264", "TFAM", "TFG", "TFIP11", "TFRC", "THOC1", "THOC3", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "TIA1", "TIAL1", "TIMELESS", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TK1", "TKT", "TLN1", "TM9SF2", "TM9SF3", "TMCO1", "TMED10", "TMED2", "TMED7", "TMEM109", "TMEM11", "TMEM126A", "TMEM14C", "TMEM199", "TMEM214", "TMEM230", "TMEM33", "TMEM43", "TMEM65", "TMEM87A", "TMEM97", "TMOD3", "TMTC3", "TMX1", "TMX2", "TNPO1", "TNPO2", "TOE1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOR1AIP2", "TP53", "TP53BP1", "TPD52", "TPD52L2", "TPI1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRIM21", "TRIM25", "TRIM27", "TRIM28", "TRIP12", "TRIP13", "TRMT10C", "TRMT11", "TRMT112", "TRMT2A", "TRMT6", "TROVE2", "TRUB1", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN6", "TSPYL1", "TSR1", "TSTA3", "TTC1", "TTC19", "TTC26", "TTC37", "TTC4", "TTI1", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE2V1", "UBE3C", "UBE4A", "UBLCP1", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UFSP2", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "UROD", "USO1", "USP10", "USP11", "USP14", "USP19", "USP28", "USP33", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VPS13A", "VPS18", "VPS26A", "VPS29", "VPS33A", "VPS35", "VPS4A", "VPS51", "VPS53", "VRK1", "VRK3", "WAPL", "WARS", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR18", "WDR3", "WDR33", "WDR36", "WDR41", "WDR43", "WDR46", "WDR5", "WDR6", "WDR61", "WDR70", "WDR73", "WDR75", "WDR77", "WDR82", "WFS1", "WIPI2", "WIZ", "WRAP53", "WTAP", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YKT6", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZDHHC13", "ZFYVE16", "ZMPSTE24", "ZMYM4", "ZNF318", "ZNF326", "ZNF512B", "ZNF598", "ZNF622", "ZNF638", "ZPR1", "ZRANB2", "ZW10", "ZYX"], "leading_proteins": ["AAR2", "AARS2", "AATF", "ABCB10", "ABCB7", "ABCC1", "ABCC4", "ABCE1", "ABHD10", "ABHD12", "ACAT1", "ACLY", "ACOT13", "ACOX1", "ACOX3", "ACTN2", "ACTR2", "ADAR", "ADD1", "ADPGK", "ADSS", "AIP", "AK1", "AK2", "AKAP12", "AKR1A1", "AKT1", "AKT1S1", "AKT2", "ALDH3A2", "ALDH5A1", "AMOT", "ANKFY1", "ANKLE2", "ANLN", "ANXA11", "ANXA2", "AP1B1", "AP1G1", "AP1M1", "AP2A2", "AP3D1", "APEH", "APEX1", "ARCN1", "ARF4", "ARFIP1", "ARFIP2", "ARHGAP17", "ARHGDIA", "ARHGEF2", "ARL1", "ARL6IP5", "ARPC3", "ASPM", "ATAD1", "ATAD3A", "ATAD5", "ATG4B", "ATP1A1", "ATP2A2", "ATP2B1", "ATP5B", "ATP5C1", "ATP5H", "ATP5I", "ATP6", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATPAF1", "ATPIF1", "ATRX", "BAG4", "BAG5", "BAG6", "BAIAP2", "BASP1", "BAX", "BCL10", "BCS1L", "BLMH", "BRIX1", "BUD31", "C12orf73", "C21orf59", "CAB39", "CALR", "CAP1", "CAPN1", "CASP2", "CASP3", "CASP6", "CBFB", "CCDC47", "CCNB1", "CCT4", "CD2AP", "CD47", "CDC42", "CDCA8", "CDK1", "CDK13", "CDK4", "CDKN2A", "CDKN2AIP", "CDS2", "CENPV", "CEP55", "CERS2", "CHAF1B", "CHEK2", "CHKA", "CHMP2A", "CHMP7", "CHORDC1", "CIRBP", "CKAP2", "CKAP5", "CLIC4", "CLNS1A", "CLP1", "CLPTM1L", "CLPX", "CLTC", "CMPK1", "CNNM3", "CNOT1", "COA3", "COASY", "COL4A3BP", "COLGALT1", "COPS3", "CORO1C", "COX2", "COX4I1", "COX6C", "COX7C", "CPNE1", "CPNE3", "CPOX", "CPSF6", "CPT2", "CRKL", "CSNK2A2", "CTBP2", "CTNNB1", "CTPS2", "CTR9", "CTSA", "CUL1", "CUL2", "CUL3", "CUL5", "CXADR", "CYB5B", "CYFIP1", "CYP51A1", "DAXX", "DCAKD", "DCD", "DCTN2", "DCXR", "DDRGK1", "DDX1", "DDX21", "DDX23", "DDX39A", "DDX3X", "DDX42", "DEK", "DENR", "DERL1", "DERL2", "DHCR24", "DHFR", "DHPS", "DHX29", "DHX30", "DHX36", "DIAPH1", "DIAPH3", "DIP2B", "DKC1", "DLAT", "DLD", "DNAJA2", "DNAJA3", "DNAJB6", "DNAJC3", "DNM2", "DOHH", "DPF2", "DPH2", "DPM1", "DPYSL3", "DRG2", "DSP", "DTL", "DYNC1H1", "DYNC1LI1", "DYNC1LI2", "EARS2", "ECSIT", "EDC3", "EHD1", "EHMT2", "EIF2AK2", "EIF3A", "EIF3D", "EIF3F", "EIF3G", "EIF3L", "EIF3M", "EIF4E", "EIF4G1", "EIF5A", "EIF6", "ELMO2", "ELOA", "ELOC", "ELP2", "EMC7", "ENO1", "ENSA", "EPPK1", "ERAL1", "ERAP1", "ERCC2", "ERCC6L", "ERGIC3", "ERO1A", "ERP44", "ESD", "EXOC2", "EXOC4", "EXOC6", "EXOSC9", "F11R", "FABP5", "FAM3C", "FAM49B", "FAM98B", "FANCD2", "FDXR", "FH", "FKBP1A", "FKBP7", "FKBP8", "FKBP9", "FLCN", "FLOT2", "FOXC1", "FTO", "FUNDC2", "FXR2", "G3BP1", "GAA", "GABARAPL2", "GALM", "GAPDH", "GATAD2A", "GBA", "GCC2", "GCN1", "GDI1", "GGCT", "GGCX", "GHITM", "GINS2", "GINS3", "GLO1", "GLRX3", "GLS", "GLTP", "GLUD1", "GMFB", "GNAI2", "GNL3L", "GOLGB1", "GOT1", "GOT2", "GPAA1", "GPI", "GRIPAP1", "GSPT1", "GSR", "H1F0", "H1FX", "H2AFY", "H2AFY2", "H4C1*", "HADH", "HDAC1", "HDAC2", "HDHD2", "HEATR1", "HEATR3", "HECTD1", "HGS", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HLA-B", "HMGA1", "HMGB1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPC", "HNRNPU", "HPS6", "HSD17B11", "HSP90AA1", "HSP90AB1", "HSPA14", "HSPA1B", "HSPA8", "HSPB1", "HSPD1", "IDE", "IDI1", "IGF2BP1", "IGF2BP2", "ILKAP", "IMPAD1", "IMPDH2", "IPO11", "IPO8", "IQGAP1", "IRF2BPL", "ISCU", "ISY1", "ITCH", "JUP", "KCTD12", "KCTD5", "KDELR1", "KDM1A", "KDSR", "KIF1A", "KIF20A", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KMT2A", "KNTC1", "KPNA1", "KPNA3", "LAMTOR1", "LARP1", "LARP4B", "LCLAT1", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LLGL1", "LONP1", "LRPAP1", "LSM2", "LTA4H", "LYPLA1", "LZTFL1", "M6PR", "MACF1", "MANF", "MAP2K1", "MAP2K2", "MAP3K7", "MAPK14", "MAPK3", "MARC1", "MARK2", "MCCC2", "MCM4", "MCTS1", "MCU", "MDH1", "ME1", "ME2", "MECP2", "MED24", "MED25", "MEPCE", "MFN2", "MFSD10", "MGEA5", "MIA3", "MIPEP", "MMGT1", "MORF4L2", "MOSPD2", "MPG", "MPRIP", "MRE11", "MRPL58", "MRRF", "MSH2", "MSH3", "MSMO1", "MSN", "MTA1", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTIF2", "MTOR", "MTPN", "MTX1", "MTX3", "MUT", "MYDGF", "MYH9", "NADK2", "NAGLU", "NAMPT", "NCAPD3", "NCAPG", "NCL", "NCSTN", "NDUFA11", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF7", "NDUFB11", "NDUFB3", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV2", "NECAP1", "NECAP2", "NEFL", "NEFM", "NELFE", "NLE1", "NLN", "NNT", "NOL8", "NOLC1", "NONO", "NOP14", "NOP53", "NPTN", "NSA2", "NSUN5", "NT5C3A", "NTMT1", "NUBPL", "NUCB2", "NUDT12", "NUDT5", "NUF2", "NUMA1", "NUP188", "NUP58", "OCRL", "OGT", "OLA1", "OPA1", "OXA1L", "OXSR1", "PABPC1", "PABPN1", "PACSIN2", "PAFAH1B2", "PAFAH1B3", "PAIP1", "PAK1IP1", "PALLD", "PARK7", "PARP1", "PARP2", "PASK", "PCBD1", "PCBP2", "PCK2", "PCLAF", "PCMT1", "PCNA", "PCYOX1", "PDCD5", "PDCD6IP", "PDHB", "PDK3", "PDS5B", "PDXK", "PFDN5", "PFDN6", "PGAM1", "PGRMC2", "PHAX", "PHB", "PHB2", "PIGK", "PIH1D1", "PIN4", "PIR", "PITHD1", "PKM", "PKMYT1", "PLA2G15", "PLEC", "PLS1", "PMPCA", "PMVK", "POLA1", "POLA2", "POLD1", "POLDIP2", "POLE", "POLR1A", "POLR1B", "POLR1C", "PON2", "PPIL1", "PPM1F", "PPP1CA", "PPP2R1A", "PPP2R5D", "PPP3CA", "PRAF2", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX5", "PRDX6", "PRIM1", "PRKAA1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKRA", "PRMT5", "PRRC1", "PSAT1", "PSMB2", "PSMC6", "PSMD10", "PSMD14", "PSMD4", "PSME1", "PSME4", "PSMG1", "PSMG3", "PTRH2", "PUM1", "PYCR1", "QKI", "RAB1A", "RAB35", "RAB39A", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB6A", "RABGAP1", "RACGAP1", "RACK1", "RAD50", "RALY", "RANBP9", "RANGAP1", "RAP1GDS1", "RASA1", "RBM10", "RBM14", "RBM15", "RBM4", "RBP1", "RDH11", "RDX", "RECQL4", "REXO2", "RFLNB", "RHOG", "RNF114", "RNF40", "ROCK2", "RPA3", "RPL10A", "RPL12", "RPL13", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL29", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL38", "RPL7", "RPL7A", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPRD1B", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS18", "RPS19", "RPS2", "RPS3A", "RPS6", "RPS7", "RPS8", "RPS9", "RPSA", "RRM2", "RSU1", "RTN1", "RTN3", "RTN4", "RUFY1", "S100A10", "SAE1", "SAP30BP", "SCAF1", "SCAMP1", "SCARB1", "SCARB2", "SCD", "SCRIB", "SDHA", "SEC22B", "SEC24A", "SEPT6", "SERBP1", "SERPINH1", "SF1", "SF3A2", "SF3A3", "SFPQ", "SFXN4", "SGPL1", "SHMT2", "SHOC2", "SHTN1", "SIN3A", "SIRT2", "SKP1", "SLC25A10", "SLC25A15", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A32", "SLC25A5", "SLC29A1", "SLC30A5", "SLC35B2", "SLC35F2", "SLC3A2", "SLC9A3R1", "SLTM", "SMARCA1", "SMARCA5", "SMC2", "SMC4", "SMC5", "SMC6", "SMPD4", "SNAP23", "SNAP29", "SNRPD1", "SNX1", "SNX27", "SNX6", "SOAT1", "SOD2", "SON", "SPC25", "SPPL2A", "SRPRA", "SRSF6", "SSB", "SSBP1", "STAM", "STAT3", "STAU1", "STK4", "STMN1", "STOML2", "STRBP", "STT3A", "STT3B", "STUB1", "STX5", "SUCLA2", "SUCLG2", "SUN1", "SURF4", "SYAP1", "SYMPK", "SYNGR2", "SYNJ2BP", "TAB1", "TALDO1", "TARDBP", "TCP1", "TDRKH", "TFIP11", "TFRC", "TIA1", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TJP1", "TKT", "TLN1", "TM9SF3", "TMEM109", "TMEM126A", "TMEM33", "TMEM65", "TNPO2", "TOMM22", "TOR1AIP1", "TOR1AIP2", "TP53", "TPP1", "TPR", "TRAP1", "TRAPPC11", "TRIM25", "TRIP13", "TRMT11", "TRMT6", "TROVE2", "TSG101", "TSPAN6", "TSPYL1", "TSTA3", "TTC26", "TTYH3", "TUBB", "TUBB4A", "TUBB4B", "TUBGCP2", "TUBGCP3", "TWF1", "TWF2", "TXLNA", "TXNRD1", "UBA2", "UBA3", "UBAP2L", "UBE2N", "UBE2S", "UBE2V1", "UBE3C", "UBR5", "UBXN1", "UCK2", "UFC1", "UGDH", "UGGT1", "UGP2", "UNC119", "UNC119B", "UNG", "UPF1", "UQCC1", "UQCR10", "UQCRB", "UQCRQ", "USP33", "UTP11", "UTP15", "VAMP7", "VAT1", "VBP1", "VCP", "VIM", "VPS13A", "VPS18", "VPS26A", "VPS33A", "VRK1", "VRK3", "WAPL", "WBP2", "WDR1", "WDR33", "WDR43", "WFS1", "WRAP53", "XPO4", "XPOT", "XRCC1", "YARS2", "YBX1", "YKT6", "YME1L1", "YTHDC2", "YWHAH", "ZADH2", "ZC3H14", "ZDHHC13", "ZMPSTE24", "ZNF318", "ZNF512B", "ZNF622", "ZPR1", "ZYX"]} \ No newline at end of file diff --git a/msigdb_gocc/advanced/idx2term.json b/msigdb_gocc/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..6e290487043d648b35291eb02a84e0132dfca9d0 --- /dev/null +++ b/msigdb_gocc/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Organelle inner membrane", "1": "Mitochondrial protein containing complex", "2": "Inner mitochondrial membrane protein complex", "3": "Intrinsic component of mitochondrial inner membrane", "4": "Intrinsic component of mitochondrial membrane", "5": "Mitochondrial envelope", "6": "Intrinsic component of organelle membrane", "7": "Cytoplasmic side of membrane", "8": "Dendritic tree", "9": "Actin based cell projection"} \ No newline at end of file diff --git a/msigdb_gocc/advanced/plot_0.png b/msigdb_gocc/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..13d1d83d9d36d2966a37cba69f0c9032a22d0397 --- /dev/null +++ b/msigdb_gocc/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:02728706a83b6f41a120a5fd237f25f3f40fa8ea5bfe64eb6cc15b513822cfa0 +size 226001 diff --git a/msigdb_gocc/advanced/plot_1.png b/msigdb_gocc/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..35bf1535021591aa72c541a8bb7f9cdb6d02b051 --- /dev/null +++ b/msigdb_gocc/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5fbcec8ace908e7bb13c380b859156d38cc2f450b7dfb9872b36362359e6246d +size 222197 diff --git a/msigdb_gocc/advanced/plot_2.png b/msigdb_gocc/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..524b41679ff56a0f969032e0ce3ebc421f436a33 --- /dev/null +++ b/msigdb_gocc/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:76268fdd251d343465d1dfa6cfd2f9c8ee593d3da9eea64ac9d2b7c0665a18e1 +size 212233 diff --git a/msigdb_gocc/advanced/plot_3.png b/msigdb_gocc/advanced/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..d4692809da4282865a35a33fb9dc9b1f726e9821 --- /dev/null +++ b/msigdb_gocc/advanced/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:488abfdc78215a61ef58bf9409d2b7994e3e5fd9c178b1c05d1912dc0b97268a +size 206101 diff --git a/msigdb_gocc/advanced/plot_4.png b/msigdb_gocc/advanced/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..3f930cc3db284066e5b8631c3b1461a1061a5e2f --- /dev/null +++ b/msigdb_gocc/advanced/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:59f32a46dcaeca3ad0e17870a1633dfd484c023723292c4828a86c2601c8bacb +size 208123 diff --git a/msigdb_gocc/advanced/plot_5.png b/msigdb_gocc/advanced/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..e650dbc6f50d4f2453b057f5596e3e6b3f63cecd --- /dev/null +++ b/msigdb_gocc/advanced/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c1ca7222934382170538105460cf3dad3e85a188d7ce763227a58c673657a44c +size 226233 diff --git a/msigdb_gocc/advanced/plot_6.png b/msigdb_gocc/advanced/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..46ef3eb048e52e5c4775c4c383fc8fd791e7037f --- /dev/null +++ b/msigdb_gocc/advanced/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2455da109afd9c260650d9d2b5455d4a3c5a174e52747de739a860315c8fbe48 +size 219185 diff --git a/msigdb_gocc/advanced/plot_7.png b/msigdb_gocc/advanced/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..e40f84ae0378daf43511c9b9bf8be04f416a6f36 --- /dev/null +++ b/msigdb_gocc/advanced/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2f73203d08abe709d4fb4d6bb9df6df578a358b443374446af4c40998244f638 +size 209851 diff --git a/msigdb_gocc/advanced/plot_8.png b/msigdb_gocc/advanced/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..90e97cf4f7ccb2d1010970726d75cada85244d7e --- /dev/null +++ b/msigdb_gocc/advanced/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5d52416363639f1742755b31d005fcf0b5558c0f9f0c503716d354f64f6fcd56 +size 214814 diff --git a/msigdb_gocc/advanced/plot_9.png b/msigdb_gocc/advanced/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..8355fa969acd1b3188c87cee7afcca5848d0daee --- /dev/null +++ b/msigdb_gocc/advanced/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f591be84ed2e93c78bb6108f9170da504f589d1e26fc882d09c30697fef73cee +size 208063 diff --git a/msigdb_gocc/basic/idx2term.json b/msigdb_gocc/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..adebb7d06a28176165c5a165f7ccf02ae43c6058 --- /dev/null +++ b/msigdb_gocc/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Organelle inner membrane", "1": "Mitochondrial protein containing complex", "2": "Inner mitochondrial membrane protein complex", "3": "Intrinsic component of mitochondrial inner membrane", "4": "Intrinsic component of mitochondrial membrane", "5": "Mitochondrial envelope", "6": "Intrinsic component of organelle membrane", "7": "Cytoplasmic side of membrane", "8": "Dendritic tree", "9": "Actin based cell projection", "10": "Extrinsic component of membrane", "11": "Membrane protein complex", "12": "Filopodium", "13": "Cytosolic ribosome", "14": "Flemming body", "15": "Respirasome", "16": "Actin filament", "17": "Rough endoplasmic reticulum", "18": "Envelope", "19": "Polymeric cytoskeletal fiber", "20": "Cytochrome complex", "21": "Chromosome centromeric region", "22": "Extrinsic component of plasma membrane", "23": "Lamellipodium", "24": "Cell body", "25": "Somatodendritic compartment", "26": "Distal axon", "27": "Rna polymerase complex", "28": "Cytosolic small ribosomal subunit", "29": "Nadh dehydrogenase complex", "30": "Ribosomal subunit", "31": "Outer membrane", "32": "Cytosolic large ribosomal subunit", "33": "Microtubule associated complex", "34": "Specific granule membrane", "35": "Neuron projection", "36": "Transporter complex", "37": "Small ribosomal subunit", "38": "Supramolecular polymer", "39": "Membrane microdomain", "40": "Condensed chromosome centromeric region", "41": "Midbody", "42": "Specific granule", "43": "Oxidoreductase complex", "44": "Intrinsic component of endoplasmic reticulum membrane", "45": "Intercellular bridge", "46": "Mitochondrion", "47": "Vesicle tethering complex", "48": "Side of membrane", "49": "Chromosomal region"} \ No newline at end of file diff --git a/msigdb_gocc/basic/plot_0.png b/msigdb_gocc/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..d7fbde6dc4d175e6252fae4412a9e51066b1529e --- /dev/null +++ b/msigdb_gocc/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:63d9ec2e0d70ea98a64841ec363c7527046378ea703a6c31f6f4f666e7b8de6a +size 145781 diff --git a/msigdb_gocc/basic/plot_1.png b/msigdb_gocc/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..5dcaff6e7d9c42ed3af249afb15f7b7fb483e1c4 --- /dev/null +++ b/msigdb_gocc/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8ca0a8dc063d12e877377ec719d4d24fca40623eb8c4b6ea1701b94b4cdcebcd +size 150709 diff --git a/msigdb_gocc/basic/plot_10.png b/msigdb_gocc/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..0edae65dfdd590df7dd72a91e0e43976be6417a9 --- /dev/null +++ b/msigdb_gocc/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:90c2a64e324bdf9fe193967073780faf1c0d752f6e42be327a68661c2997393c +size 135525 diff --git a/msigdb_gocc/basic/plot_11.png b/msigdb_gocc/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..0d3eb3a8d460ab90c17c62ddc2f535be5999c9bd --- /dev/null +++ b/msigdb_gocc/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7245d26e7750a357b1d34bb3444476324e21def437af374c83949716937233dd +size 138362 diff --git a/msigdb_gocc/basic/plot_12.png b/msigdb_gocc/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..14e3c35e73a582a90c5a206bf7a4383de523b098 --- /dev/null +++ b/msigdb_gocc/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6491b1477190c471c1430eb835d5eca0441236caeb5d1df147abac88abb64374 +size 130101 diff --git a/msigdb_gocc/basic/plot_13.png b/msigdb_gocc/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..77fcbde8091b36311cb7c72f31e4f78d1d7f4631 --- /dev/null +++ b/msigdb_gocc/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ae7fe6cfa224fc8e601575280b5767e351b30f5c0105dbbf0ebdcb6cae1d410b +size 140223 diff --git a/msigdb_gocc/basic/plot_14.png b/msigdb_gocc/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..dd8a7a649cde7a0d76a99ba3c7d7804cfeeba408 --- /dev/null +++ b/msigdb_gocc/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:920accb139d46493d63a4d16ca4f9790e489e72fa79a47565bdbd100ed4bb033 +size 131020 diff --git a/msigdb_gocc/basic/plot_15.png b/msigdb_gocc/basic/plot_15.png new file mode 100644 index 0000000000000000000000000000000000000000..ec7b11a64a3cb3981e8fa938ef47dd62373ce799 --- /dev/null +++ b/msigdb_gocc/basic/plot_15.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0dae29460fa386eb01491e59b9bee59644cbd7759ff539d4dd78057d190c661c +size 138771 diff --git a/msigdb_gocc/basic/plot_16.png b/msigdb_gocc/basic/plot_16.png new file mode 100644 index 0000000000000000000000000000000000000000..40798c17a2ba819d6ae6975fa9c88a770fe21306 --- /dev/null +++ b/msigdb_gocc/basic/plot_16.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3fb3d757ce85661cab4683a94f0b52f6567a0ddfe4c12efc7b70418e88f1a003 +size 120174 diff --git a/msigdb_gocc/basic/plot_17.png b/msigdb_gocc/basic/plot_17.png new file mode 100644 index 0000000000000000000000000000000000000000..e84c7c4fe3987908cd39ecc002071484912edc3b --- /dev/null +++ b/msigdb_gocc/basic/plot_17.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:06c8ef4f2848b59b4000fb063cea331775a59b15d213c92daacc90864a83d393 +size 140193 diff --git a/msigdb_gocc/basic/plot_18.png b/msigdb_gocc/basic/plot_18.png new file mode 100644 index 0000000000000000000000000000000000000000..7f867d81f6eb5480fe183d42fc467e66451716c3 --- /dev/null +++ b/msigdb_gocc/basic/plot_18.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2a33cc6239c24861a35aa23e2bf4ff75843309e981815622e96d9863f1c7254f +size 130099 diff --git a/msigdb_gocc/basic/plot_19.png b/msigdb_gocc/basic/plot_19.png new file mode 100644 index 0000000000000000000000000000000000000000..06a28fcba6aed6285421ae6fef4ebbaa3ddc4509 --- /dev/null +++ b/msigdb_gocc/basic/plot_19.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3127f5aff6b1f1a49996bbec8f593ee2e826568aed02005e9b95e6c879552317 +size 142419 diff --git a/msigdb_gocc/basic/plot_2.png b/msigdb_gocc/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..659480788bb2260dddfdc541466d908e89808f20 --- /dev/null +++ b/msigdb_gocc/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a8ca5fb8109b025d58f51d39a7cb72910c6b50d5357aaabf772dde7e36c05eaf +size 144775 diff --git a/msigdb_gocc/basic/plot_20.png b/msigdb_gocc/basic/plot_20.png new file mode 100644 index 0000000000000000000000000000000000000000..7990d7e7ffc2374e6f1973dcaa14ac0ad2a4a500 --- /dev/null +++ b/msigdb_gocc/basic/plot_20.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:49849141912789738005e22a99d05da36ecaf7ad68469b400ef74ea6f93fca71 +size 133875 diff --git a/msigdb_gocc/basic/plot_21.png b/msigdb_gocc/basic/plot_21.png new file mode 100644 index 0000000000000000000000000000000000000000..e19a05c6371890e4167b138da04d6792a4f500ae --- /dev/null +++ b/msigdb_gocc/basic/plot_21.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:20b34556109fbae8a2e4541ffeffab9082e5bb1a09b6206475d9bf827df95914 +size 142195 diff --git a/msigdb_gocc/basic/plot_22.png b/msigdb_gocc/basic/plot_22.png new file mode 100644 index 0000000000000000000000000000000000000000..bcb3a81775e3922915b82d7b6b47fcaae0e9bcdd --- /dev/null +++ b/msigdb_gocc/basic/plot_22.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3fbe6bea66c4b61eefbb01fb75389c0c78ac3fe7b3c109edd6655effc4a1fdc9 +size 139486 diff --git a/msigdb_gocc/basic/plot_23.png b/msigdb_gocc/basic/plot_23.png new file mode 100644 index 0000000000000000000000000000000000000000..ba0d9be974fa188fe0fb049d4c5198ec514bf2fe --- /dev/null +++ b/msigdb_gocc/basic/plot_23.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9de4119f08926a3b861c38e5073a9ddfcf46678a21b88fe050f1d01046943d86 +size 134234 diff --git a/msigdb_gocc/basic/plot_24.png b/msigdb_gocc/basic/plot_24.png new file mode 100644 index 0000000000000000000000000000000000000000..11b4f7d87cf2fa0cfdbf59a07808367a979b299d --- /dev/null +++ b/msigdb_gocc/basic/plot_24.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:42166d3b0fadc117e7d2bc4ef2de1b4e5c223c150b499cd514491c1ebd8223f3 +size 133152 diff --git a/msigdb_gocc/basic/plot_25.png b/msigdb_gocc/basic/plot_25.png new file mode 100644 index 0000000000000000000000000000000000000000..df965f2ed9f07525389f9ec8a15edc8f7ac02615 --- /dev/null +++ b/msigdb_gocc/basic/plot_25.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b690f0eee88cc77716fb82ed059b1f3798e688d4b578ec49b6204c9df7e5a1e4 +size 144573 diff --git a/msigdb_gocc/basic/plot_26.png b/msigdb_gocc/basic/plot_26.png new file mode 100644 index 0000000000000000000000000000000000000000..d524fee90e2de9576e5f1bb78921585bbaabb2dc --- /dev/null +++ b/msigdb_gocc/basic/plot_26.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:05b51f92110ba863684e33f42075186ee5bc5d5e70b478ac34c3a1cd6715125d +size 139275 diff --git a/msigdb_gocc/basic/plot_27.png b/msigdb_gocc/basic/plot_27.png new file mode 100644 index 0000000000000000000000000000000000000000..fdf649213d9165c31d2e69c0532f7c2efb972172 --- /dev/null +++ b/msigdb_gocc/basic/plot_27.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b6e748b4d23f36d252dd63d592e77f0e544c8d1915b28d83462737ce3d99f7f7 +size 142494 diff --git a/msigdb_gocc/basic/plot_28.png b/msigdb_gocc/basic/plot_28.png new file mode 100644 index 0000000000000000000000000000000000000000..1117cba277d759074278a5f820b92c5cb862bba0 --- /dev/null +++ b/msigdb_gocc/basic/plot_28.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4d430bf724a313d81530bbf3737e40cc3d3ccae5302c7e062f119a512e778bd6 +size 145966 diff --git a/msigdb_gocc/basic/plot_29.png b/msigdb_gocc/basic/plot_29.png new file mode 100644 index 0000000000000000000000000000000000000000..d6defe7cfcd7c463044621985be7b9d49a429698 --- /dev/null +++ b/msigdb_gocc/basic/plot_29.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0e6572c0093abf4f46c8fb81a9b485af78339702b0bc6ed2c19ea9d713d1a762 +size 139746 diff --git a/msigdb_gocc/basic/plot_3.png b/msigdb_gocc/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..9eea0720f31e968d6df38475b60001bd5926dcb3 --- /dev/null +++ b/msigdb_gocc/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b1940cd34904f35cd1ab5c730010ae424b1807d17c41a8f21040ec66c54a991b +size 140373 diff --git a/msigdb_gocc/basic/plot_30.png b/msigdb_gocc/basic/plot_30.png new file mode 100644 index 0000000000000000000000000000000000000000..74bb44bfc77c5b6de9e92509e386ae84ef6600e6 --- /dev/null +++ b/msigdb_gocc/basic/plot_30.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:cd0b41e122bd4352b297364766926fd6e10030b542aa3a4a4573af02b48f659f +size 142654 diff --git a/msigdb_gocc/basic/plot_31.png b/msigdb_gocc/basic/plot_31.png new file mode 100644 index 0000000000000000000000000000000000000000..8114aaa3ed3ca499fa3ade18c541b1ef04e2cd79 --- /dev/null +++ b/msigdb_gocc/basic/plot_31.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f15a1ba559b46bb04f292eb2bd1d909e062e0b82dc0e5efd0997b49acda59d1d +size 136668 diff --git a/msigdb_gocc/basic/plot_32.png b/msigdb_gocc/basic/plot_32.png new file mode 100644 index 0000000000000000000000000000000000000000..08cea48b672d17a055a4d47c9da1c04b8d7b1784 --- /dev/null +++ b/msigdb_gocc/basic/plot_32.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d656631f10eed176649115bb21effb3c0e35d9151d052532863967bbb4483842 +size 149531 diff --git a/msigdb_gocc/basic/plot_33.png b/msigdb_gocc/basic/plot_33.png new file mode 100644 index 0000000000000000000000000000000000000000..298449b96ab42fdb2f8f3904f20b5803c7b65309 --- /dev/null +++ b/msigdb_gocc/basic/plot_33.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:647ce32869b52d421d80b09dd528afffe74c5eed69b325641830aa2870a28c1c +size 145406 diff --git a/msigdb_gocc/basic/plot_34.png b/msigdb_gocc/basic/plot_34.png new file mode 100644 index 0000000000000000000000000000000000000000..33103a6a3541a5d62a52b5baf04f18a1d4615c63 --- /dev/null +++ b/msigdb_gocc/basic/plot_34.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:035a04fd5d3db7848bc021d489ec460181c9202e8b3e8b2bb901e2337d3c2378 +size 138186 diff --git a/msigdb_gocc/basic/plot_35.png b/msigdb_gocc/basic/plot_35.png new file mode 100644 index 0000000000000000000000000000000000000000..6385c2e0db24a23b17926dff7bc38d167c4491cb --- /dev/null +++ b/msigdb_gocc/basic/plot_35.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bdb34e689583638aa8651d490dce1af48ec922701d171d90f88ae2b4557e3027 +size 138611 diff --git a/msigdb_gocc/basic/plot_36.png b/msigdb_gocc/basic/plot_36.png new file mode 100644 index 0000000000000000000000000000000000000000..dd56bd6923d1128b1f437bdb9d892e52d3b06f2a --- /dev/null +++ b/msigdb_gocc/basic/plot_36.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a65307d6ddb15fa347665a44d10ab8bd8d83bac1a72ce17250dca5799eb977c1 +size 137932 diff --git a/msigdb_gocc/basic/plot_37.png b/msigdb_gocc/basic/plot_37.png new file mode 100644 index 0000000000000000000000000000000000000000..74c3c769058ce937351c7b884cd5b92dfa0ed8ca --- /dev/null +++ b/msigdb_gocc/basic/plot_37.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:600798ece75f5093fad2dec9230135f798b886e3fc139d32816b5174ec3b7ec9 +size 142971 diff --git a/msigdb_gocc/basic/plot_38.png b/msigdb_gocc/basic/plot_38.png new file mode 100644 index 0000000000000000000000000000000000000000..3931f93754b1b4b249a0717e17db5677790b6339 --- /dev/null +++ b/msigdb_gocc/basic/plot_38.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5f8ff98d362b124ed3df1aea607db505a35292feefb2935f4bf5ae9980a9756d +size 142448 diff --git a/msigdb_gocc/basic/plot_39.png b/msigdb_gocc/basic/plot_39.png new file mode 100644 index 0000000000000000000000000000000000000000..88fc4d7edd50cb0006a52897302aaf7a7debea0b --- /dev/null +++ b/msigdb_gocc/basic/plot_39.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d28fb01dcc2bacfe3d1f06435fbd75bff6ec1cde445a6ea572590dd1911c668b +size 142306 diff --git a/msigdb_gocc/basic/plot_4.png b/msigdb_gocc/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..7b88e3162287bf4d1a866fbca25e59da14faa269 --- /dev/null +++ b/msigdb_gocc/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a7c5e117b395c72074363d61c6a5398854fcb4fdfd6c922561ffe5d5fd2bca99 +size 142588 diff --git a/msigdb_gocc/basic/plot_40.png b/msigdb_gocc/basic/plot_40.png new file mode 100644 index 0000000000000000000000000000000000000000..93aca04d1b9a6cb351881d37a64993b8e38e6c6f --- /dev/null +++ b/msigdb_gocc/basic/plot_40.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:24c7cb18daeecf62b91fbb968d442104dc6527cc89db60351f98894cfac23ef3 +size 153203 diff --git a/msigdb_gocc/basic/plot_41.png b/msigdb_gocc/basic/plot_41.png new file mode 100644 index 0000000000000000000000000000000000000000..b72c59b6de3c00a78d3d691b1e95d303dae83550 --- /dev/null +++ b/msigdb_gocc/basic/plot_41.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:db5af9bd1cd96b6e82775329dca1b3d599ccd15ac597235be08a74605dc25888 +size 138980 diff --git a/msigdb_gocc/basic/plot_42.png b/msigdb_gocc/basic/plot_42.png new file mode 100644 index 0000000000000000000000000000000000000000..e9a42e307f89ac602202a5bb55fb96c0385df0e4 --- /dev/null +++ b/msigdb_gocc/basic/plot_42.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:09ebbfbf57a42f8284c6e4ccb7791543fa039be4ae5d1938389ecd5966c2fc7a +size 142364 diff --git a/msigdb_gocc/basic/plot_43.png b/msigdb_gocc/basic/plot_43.png new file mode 100644 index 0000000000000000000000000000000000000000..71345e89348d06bed65c4f6fba55a0985c51ed70 --- /dev/null +++ b/msigdb_gocc/basic/plot_43.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:56c328cdbcf1398c7cb5f6c1c0d9659e113fdce06f321af98e8bb194536b1424 +size 147864 diff --git a/msigdb_gocc/basic/plot_44.png b/msigdb_gocc/basic/plot_44.png new file mode 100644 index 0000000000000000000000000000000000000000..52f0e7ad0e766b91cce6294edc5b7dea58f9681e --- /dev/null +++ b/msigdb_gocc/basic/plot_44.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:84763a7789616d6cd6204c2b8ec586774aa0074bb648fff954cee79da03cee9d +size 147626 diff --git a/msigdb_gocc/basic/plot_45.png b/msigdb_gocc/basic/plot_45.png new file mode 100644 index 0000000000000000000000000000000000000000..bf23eae72afc710f9c4d606da58019b3e96d3421 --- /dev/null +++ b/msigdb_gocc/basic/plot_45.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:583aaddfbe02a4b82b59806171c3141d722f6e340d0b0d36b1d336a4c71586dc +size 140712 diff --git a/msigdb_gocc/basic/plot_46.png b/msigdb_gocc/basic/plot_46.png new file mode 100644 index 0000000000000000000000000000000000000000..6a9fbdd170712720c8f0714bedb1ecfe62745592 --- /dev/null +++ b/msigdb_gocc/basic/plot_46.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:05efb58acf345032512518f9ebfb10f62d7317d6675a3408fc083dfb75c6505b +size 137163 diff --git a/msigdb_gocc/basic/plot_47.png b/msigdb_gocc/basic/plot_47.png new file mode 100644 index 0000000000000000000000000000000000000000..96d8ae2ffe3006f1b68d04cb3c30dbf2f507c1fc --- /dev/null +++ b/msigdb_gocc/basic/plot_47.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a7eaaee2fd120f608844e62720f99ee0c93889da50c27ccea845b4ab70c7d486 +size 140274 diff --git a/msigdb_gocc/basic/plot_48.png b/msigdb_gocc/basic/plot_48.png new file mode 100644 index 0000000000000000000000000000000000000000..3635739f6aa672e766a94b35402c81d8c64c58fc --- /dev/null +++ b/msigdb_gocc/basic/plot_48.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:97849ab28325106f0946c4efb80a595198c9bffb2900e1fcedaaeea947cf256e +size 144571 diff --git a/msigdb_gocc/basic/plot_49.png b/msigdb_gocc/basic/plot_49.png new file mode 100644 index 0000000000000000000000000000000000000000..a41ab50041cec0a9534bba988b096c9486cde728 --- /dev/null +++ b/msigdb_gocc/basic/plot_49.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f8240217d565af8fcbbfe7d460eaf003c7827717be91057b90862e04df2b0719 +size 147652 diff --git a/msigdb_gocc/basic/plot_5.png b/msigdb_gocc/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..ed8478507a9acf8de35b2be870ea3a46022b23df --- /dev/null +++ b/msigdb_gocc/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0d4ed224fd7c8ca8ebdd47c3da74f77d355243d283d09e9abc0ed7c40ce708af +size 144121 diff --git a/msigdb_gocc/basic/plot_6.png b/msigdb_gocc/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..ba5c03b2b0f97a9d2fbd220130be5c137d7465f9 --- /dev/null +++ b/msigdb_gocc/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5fa9adb0084030a51355fe81c95364c84e188f2bd9c03efc38ba0b0facb61268 +size 149348 diff --git a/msigdb_gocc/basic/plot_7.png b/msigdb_gocc/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..e9e093288a6766c327dc99e02998c383cc237cf4 --- /dev/null +++ b/msigdb_gocc/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bcc47ea6cad1e7ea730518c80b0ce059bee837c588aaabaedbdde9d937a8e1f7 +size 144906 diff --git a/msigdb_gocc/basic/plot_8.png b/msigdb_gocc/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..0adb47694275d0c210d999a7c389ac5c43db0c69 --- /dev/null +++ b/msigdb_gocc/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ab6051631fbbd5b6efb7a46d1a0832fb5d8a55d4b26fc5e05f3c1acd0881f60e +size 135327 diff --git a/msigdb_gocc/basic/plot_9.png b/msigdb_gocc/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..47112d42da4e87bc2bfed02e53175637c35458a6 --- /dev/null +++ b/msigdb_gocc/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e1477a3371908e4b18b56d8b5a8c9b7452db483da498496d45a0177c90a6f630 +size 136957 diff --git a/msigdb_gocc/consensus.joblib b/msigdb_gocc/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..911bd33c76f18ce006a29907f032d9d6e215d685 --- /dev/null +++ b/msigdb_gocc/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ef001c608d5ca554dcabe1fe1b49f95b011292ed5200eb538c47d9f5c910938c +size 125619 diff --git a/msigdb_gocc/df_merge.tsv b/msigdb_gocc/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..64772de5ed711cf510d58c845714d965bb5323e8 --- /dev/null +++ b/msigdb_gocc/df_merge.tsv @@ -0,0 +1,24 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Organelle inner membrane 43 214 4.384582058743314 1.1620867190309523e-05 79.6747572815534 237.5995145631068 1.5941979045672914 0.3906136455525962 32.81710191865129 21.467005610038825 2.570753705211445 0.4244355950981394 0.0438407218510411 3.4605614463464185e-05 5.604004198597347e-07 1.6326084742067522e-11 1.5873610217691734e-13 +Mitochondrial protein containing complex 26 140 4.215771018079805 2.489262426697003e-05 45.62621359223301 153.59708737864077 0.8032126729603613 0.4024101172023991 21.080430630469312 12.423857071229754 2.191669513941161 0.4117346592056412 0.0250098077673959 2.176198162966284e-05 0.0001145577063945 6.5642193420016115e-09 3.870144346723177e-09 +Inner mitochondrial membrane protein complex 14 73 4.096068744436091 4.202251930474077e-05 27.97087378640777 75.4635922330097 1.520604987560478 0.2664687480104057 12.043574857699111 6.447783897817093 2.3558486082891616 0.3692317407906862 0.0129462534325135 0.0003693408071895 0.0002087812415366 4.53566184441333e-07 2.44130433579739e-07 +Intrinsic component of mitochondrial inner membrane 7 30 3.4183436200061883 0.0006300351075192 13.946601941747574 31.446601941747577 1.7062420859184484 0.2149692261988765 6.992163651608136 3.3601842163433866 1.8185871159494191 0.3070405082296492 0.0049038838759844 8.49425410120894e-05 9.134926391907227e-05 1.916591951758053e-05 0.0001013319520925 +Intrinsic component of mitochondrial membrane 7 44 3.1472658072335764 0.0016480506795406 20.225728155339805 46.883495145631066 1.6360090381123027 0.2606204408334349 9.735582728924424 5.567853242112672 2.0682718238883013 0.3438986948818692 0.0077481365239927 0.0005014755444469 0.0007875587043704 0.0005181546437862 1.8558855498243743e-05 +Outer mitochondrial membrane protein complex 2 15 2.895253275533084 0.0037885271844029 7.157766990291262 15.730582524271844 1.3245491566248977 0.2112996285983387 3.5767402396348245 0.8689557679680192 1.477430451036954 0.2853006280851536 0.0019615535503777 0.0039064712270754 0.0143432947155656 0.0109201949227154 0.0134379436070106 +Mitochondrial envelope 66 275 2.88662245154191 0.0038940118800432 98.51456310679612 309.05582524271847 1.3784407074331837 0.4315621435689855 37.853540978552445 29.592036616547553 2.6690149272426917 0.4358105924461398 0.0626716359340205 0.0026072607363854 0.000695930990617 2.8454596291479697e-07 1.9563224324373408e-10 +Intrinsic component of organelle membrane 28 118 2.859740294202851 0.0042398806877144 52.51699029126213 129.34223300970874 2.0732064315361294 0.2796588394070637 24.692225942786415 15.820346456508432 2.8130846896968285 0.39829365000917 0.0295213809334347 0.0004745534237256 0.0004368902646458 0.0002654422682373 0.000101556485758 +Cytoplasmic side of membrane 9 39 2.698279464856752 0.0069698901774963 9.41504854368932 42.19660194174757 -0.1807776279439089 0.7134809004519825 5.030013486786607 6.410147303549281 0.6139095052503951 0.2765436923203467 1.0 0.1294383689627619 0.0343035498836937 0.0375402888554441 0.1026152882118644 +Dendritic tree 12 93 2.478826012079884 0.0131815587824628 22.95873786407767 107.45145631067962 -0.0089298880544856 0.7901437474135781 9.15114435834159 11.344776515640968 0.5591604100280799 0.2700884124193979 1.0 0.0221795652359765 0.0138913042318164 0.4213540829870468 0.4749178287054338 +Mib complex 1 10 2.478014316552253 0.0132115843970506 4.669902912621359 10.016990291262136 0.8674199579421746 0.3102009046029466 2.3929035436504367 0.6011337749949848 1.2568635951567688 0.31203902687269 0.0012750098077396 0.0595353304203936 0.1135034587553153 0.0362803923956974 0.0215291267260604 +Dendrite cytoplasm 1 10 2.457630048226484 0.0139857163421286 2.779126213592233 10.820388349514564 0.6421759346520178 0.4909623397232819 2.094201707070112 0.8165591106732504 0.7456922507906857 0.2969723837010567 1.0 0.1029565435856987 0.0187610509174583 0.1010759627458981 0.0940975482419373 +Neuron projection terminus 1 14 2.3207063250403457 0.0203026991299706 3.8762135922330097 15.04126213592233 0.624809000126854 0.5196547165726655 2.5191918169700847 1.8839501877506035 0.7569576543392686 0.3150927785903101 1.0 0.2436179272361805 0.1027089200496805 0.4062590361914209 0.5387259637770934 +Actin based cell projection 5 39 2.1873676860805635 0.0287156931655192 11.718446601941748 45.779126213592235 -0.1213909094288503 0.6383498944471516 6.023284069759015 5.127240330943596 0.7781705747927129 0.3071099512003558 1.0 0.4580565166404663 0.334228639413646 0.0839258598118062 0.162241573201418 +Extrinsic component of membrane 10 52 2.1521304967535437 0.0313870778144957 14.572815533980584 60.519417475728154 -0.3357404886496541 0.6844347037125864 6.960152801787093 8.34842649266219 0.5928536030737548 0.2866914611282402 1.0 0.2407056305689534 0.1115366196745588 0.3275531027136859 0.3505778260376762 +Excitatory synapse 0 5 2.1243933397104047 0.0336372664668758 1.305825242718447 5.067961165048544 0.7953512276346466 0.4272224812891962 1.179791428227925 0.8869292057247719 0.8699509292644302 0.3159178070156055 1.0 0.0683810764565047 0.1297953400165049 0.3006122829361112 0.5195845375548764 +Membrane protein complex 56 261 2.1232193772291152 0.0337354729435079 80.6747572815534 286.40291262135923 0.8072324880333213 0.5482017098759524 27.14508025817277 25.65052264389531 1.8803092756171496 0.4277745875695662 0.0656139662595216 0.0120237986951698 0.0081404696566835 0.0020985780581192 1.1140271953654132e-05 +Filopodium 6 25 2.094740206650681 0.0361940929924486 8.266990291262136 30.62621359223301 0.052797672907694 0.5971897314642494 4.612833266819705 3.808663123634042 0.8617045359290354 0.3067477038209127 1.0 0.3154415256826839 0.524726110047104 0.1193890875126746 0.0862679120364619 +Postsynaptic cytosol 0 5 2.0381618604423672 0.0415337483359705 1.0655339805825244 5.839805825242719 0.6842461209696534 0.4705435342470324 1.4888180156744395 0.7231054665083247 0.8090294271856947 0.3031424553191165 1.0 0.0461123069087121 0.088498207465679 0.2120396274437268 0.3865233555305862 +Tim23 mitochondrial import inner membrane translocase complex 2 6 2.033292911127602 0.0420229389439201 2.2694174757281553 6.342233009708738 1.5180442383336388 0.125307709046494 1.369833329272529 0.8106469094037756 1.2674744491900518 0.2021471972412396 1.0 0.0011617774889038 0.0043816077243747 0.0018476819527472 0.0133323571945306 +Schaffer collateral ca1 synapse 3 14 1.9922682081654493 0.0463416379369554 3.2888349514563107 15.04611650485437 0.526101921661134 0.5717891227457014 2.2676645532699578 1.9195745549114556 0.7194455680396641 0.3088986439388705 1.0 0.1762218760282218 0.0546703746725879 0.0714119401595937 0.0439890696876026 +Lateral plasma membrane 1 18 1.9783770673591363 0.0478861848296832 5.293689320388349 20.524271844660195 -0.078866217759487 0.7045704920367751 3.3419456835834223 2.3538634228601967 0.6536155911864782 0.2766230208535195 1.0 0.0230307909848423 0.0774829110895131 0.1129876972778286 0.4285758853451424 +Rna polymerase ii core complex 0 5 1.973804184891184 0.048404012818465 3.233009708737864 6.764563106796117 -0.5663471369447821 0.5199082545434907 1.7951059870548338 1.2189469247021516 0.713321533974658 0.2953691258537805 1.0 0.0683810764565047 0.1297953400165049 0.3006122829361112 0.5195845375548764 diff --git a/msigdb_gocc/metrics.json b/msigdb_gocc/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..48168b83987a8334166cc4338e46600f8f503359 --- /dev/null +++ b/msigdb_gocc/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2772, + "annotations_size": 889, + "title": "Average number of proteins per term", + "value": 25.742407199100114 +} \ No newline at end of file diff --git a/msigdb_gocc/paths.json b/msigdb_gocc/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..ea4504b2e675e3f0cdd306bfc163224b69cb4424 --- /dev/null +++ b/msigdb_gocc/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gocc/fragment/C321/C321_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gocc/result.tsv b/msigdb_gocc/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..9b6115754b7c441783da5b200c6f53c2ce6a4439 --- /dev/null +++ b/msigdb_gocc/result.tsv @@ -0,0 +1,274 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Organelle inner membrane 0.4926131553022488 4.384582058743314 1.1620867190309523e-05 0.0102778293636724 0.0088525917584225 214 Q13505,O95674,O95202,O60830,Q6PI78,Q9Y276,Q99595,Q9BQ95,Q96DV4,P14927,Q9NVI7,Q9Y5L4,Q9Y3D9,Q6P1L8,Q6P4A7,P00846,Q5JTV8,Q14728,Q9Y2R5,O75844,P22570,O75027,Q9NRX2,Q86Y39,Q8NE86,Q69YU5,Q96TA2,Q9BQT8,Q9NX14,Q9Y584,Q13084,O14925,Q9UDW1,O75489,Q9BYD2,Q70HW3,Q9NQ50,Q15070,Q9H1E5,P56385,O43676,O94901,Q5HYI7 43 +Mitochondrial protein containing complex 0.528015574976205 4.215771018079805 2.489262426697003e-05 0.0218867502971328 0.0088525917584225 140 Q13505,O60830,Q9Y276,Q99595,Q96DV4,P14927,Q9Y5L4,Q9HCC0,Q6P1L8,P00846,Q9NS69,Q9Y2R5,Q9NRX2,Q86Y39,Q8NE86,Q9NX14,Q9Y584,Q13084,O14925,Q9UDW1,O75489,Q9BYD2,Q9NQ50,P56385,O43676,Q5HYI7 26 +Inner mitochondrial membrane protein complex 0.6383946449684395 4.096068744436091 4.202251930474077e-05 0.0366695740785642 0.0088525917584225 73 Q13505,O60830,O14925,Q9UDW1,Q99595,O75489,P14927,Q86Y39,O43676,Q8NE86,P00846,Q9NX14,Q9Y584,Q5HYI7 14 +Intrinsic component of mitochondrial inner membrane 0.7592375527501857 3.4183436200061883 0.0006300351075192 0.428949553985215 0.0207444892809114 30 Q13505,O60830,Q99595,Q8NE86,Q15070,Q6P4A7,Q5HYI7 7 +Intrinsic component of mitochondrial membrane 0.6213816508458119 3.1472658072335764 0.0016480506795406 0.7692281400601576 0.0395977582192336 44 Q13505,O60830,Q99595,Q8NE86,Q15070,Q6P4A7,Q5HYI7 7 +Outer mitochondrial membrane protein complex 0.8143450175159904 2.8952532755330833 0.0037885271844029 0.9657612319248275 0.0781925823095901 15 Q13505,Q9NS69 2 +Mitochondrial envelope 0.3877383768329669 2.88662245154191 0.0038940118800432 0.9688373248465196 0.0781925823095901 275 Q13505,O95674,Q13057,O60830,O95202,Q6PI78,Q9Y276,Q99595,Q8NBU5,Q9BQ95,Q96DV4,P14927,Q9NVI7,Q9Y5L4,Q9Y3D9,Q6P1L8,Q6P4A7,P00846,P82664,Q9NRK6,Q9NS69,Q9Y2R5,Q9BWH2,Q5VT66,P57105,P36551,P22570,P51970,O75027,Q9NRX2,Q86Y39,Q9H2D1,Q8NE86,Q69YU5,Q9Y2R0,Q96TA2,Q5XKP0,Q9BQT8,Q9NX14,Q9Y584,Q9UBX3,O14949,Q13084,P13073,O14925,P82675,Q9UDW1,O75489,Q9BYD2,Q70HW3,Q9NQ50,Q15070,Q9BX68,Q9UDX5,P56385,P23786,O95140,O43169,P09669,O43676,P09601,Q9Y2Q9,Q96RL7,O15294,Q9Y3B8,Q5HYI7 66 +Intrinsic component of organelle membrane 0.4591772658598523 2.859740294202851 0.0042398806877144 0.9771148530355338 0.0785261235703774 118 Q13505,O60830,Q99595,O76024,Q6P4A7,Q9NRK6,Q9BWH2,P57105,O75844,Q92643,Q8N4V1,Q8TCT8,Q8NE86,Q9Y2R0,Q5XKP0,O14925,Q15070,Q9BUN8,Q96A33,Q9NPA0,P20339,O00767,O95140,Q8TB61,Q9Y282,O95470,O94901,Q5HYI7 28 +Cytoplasmic side of membrane 0.5726049913210196 2.6982794648567516 0.0069698901774963 0.9980066263241024 0.1193340493203255 39 P61353,P31749,P14923,Q8TCT8,Q08209,Q9H0H5,P36507,P04899,P20339 9 +Dendritic tree 0.4406054518067084 2.478826012079884 0.0131815587824628 0.9999924678096156 0.165423922943352 93 Q9UQB8,Q4V328,Q7KZI7,O95793,Q9H2U1,Q9Y639,Q08209,P35609,P04899,Q9P265,P20339,Q8N2K0 12 +Mib complex 0.8599985862800127 2.478014316552253 0.0132115843970506 0.9999926688224422 0.165423922943352 10 Q13505 1 +Dendrite cytoplasm 0.8552821960875682 2.457630048226484 0.0139857163421286 0.9999963510291764 0.1718963488583328 10 Q9UQB8 1 +Neuron projection terminus 0.7088150641009264 2.3207063250403457 0.0203026991299706 0.9999999879577024 0.2107809804062744 14 Q9UQB8 1 +Neuronal dense core vesicle 0.8938628158844761 2.2466969584022136 0.0246594007761378 0.999999999770938 0.2307600767367002 2 Q96RL7 1 +Dense core granule 0.8938628158844761 2.2466969584022136 0.0246594007761378 0.999999999770938 0.2307600767367002 2 Q96RL7 1 +Actin based cell projection 0.5104422930622587 2.1873676860805635 0.0287156931655192 0.9999999999943646 0.2562785627847599 39 Q9UQB8,P78310,P26038,P35609,Q96A65 5 +Extrinsic component of membrane 0.4901859896228362 2.1521304967535433 0.0313870778144957 0.999999999999513 0.2632369073310071 52 Q4V328,O95747,P31749,P14923,Q08209,Q9H0H5,Q96RL7,P63218,P04899,Q96EY1 10 +Membrane protein complex 0.3561810514675824 2.1232193772291152 0.0337354729435079 0.9999999999999436 0.2726439586070782 261 Q13505,O60830,Q9Y276,Q99595,P14927,P67812,Q6IAA8,P00846,P63218,P04899,Q9NS69,Q92643,P51970,Q13596,Q8N4V1,Q9P253,Q86Y39,Q92542,Q8NE86,P04844,Q5XKP0,Q9NX14,Q9Y584,O14949,Q8N2K0,O15498,P04843,P21281,P13073,O14925,Q9UDW1,O75489,Q8TCJ2,Q9BUN8,Q9NPA0,Q8NC96,P56385,O95721,O94973,P08195,O75436,Q8WUX9,O00161,O75306,P09669,O43633,Q9C0H2,P14923,P61923,O43676,Q9NVZ3,O14745,Q04323,P42574,O94901,Q5HYI7 56 +Filopodium 0.5872804709293548 2.094740206650681 0.0361940929924486 0.999999999999994 0.2847482183211229 25 Q9UQB8,Q6IBS0,P78310,P26038,O14745,P35609 6 +Tim23 mitochondrial import inner membrane translocase complex 0.8662459261443561 2.033292911127602 0.0420229389439201 1.0 0.3053983242241269 6 O60830,Q99595 2 +Schaffer collateral ca1 synapse 0.6466603077710341 1.9922682081654497 0.0463416379369554 1.0 0.3140884919698073 14 Q9UQB8,Q9Y639,P07196 3 +Lateral plasma membrane 0.6145147450116889 1.9783770673591363 0.0478861848296832 1.0 0.3176926739820028 18 Q7KZI7 1 +Rpap3 r2tp prefoldin like complex 0.8158582887295013 1.943351307791916 0.0519737261976476 1.0 0.3220907426665014 7 O15212,P19388 2 +Escrt iii complex 0.825631768953067 1.9410999128675095 0.0522461596415309 1.0 0.3220907426665014 2 Q8WUX9 1 +Cytosolic ribosome 0.4181793809319568 1.9317796309040904 0.0533867112208461 1.0 0.3220907426665014 77 P62906,P47914,P18077,P62249,P62910,Q9Y3U8,P62899,P62753,P62424,P62841,P32969,P63173,P62263,P62081,P15880,P30050,P62241,P35268,P62244,P62829,P62269,P39019,P62750,P61247,P08865,Q7Z478,P62277,P05388,P46781,P61353,P42766,P18124,P26373,P05387,P51116 35 +Flemming body 0.614510576440777 1.9283028212910216 0.0538174711073997 1.0 0.3220907426665014 17 Q96KP1,Q02241,Q53EZ4,Q9H0H5,Q8TAG9,Q96A65 6 +Equatorial microtubule organizing center 0.8212996389891682 1.9214486289068131 0.0546751728631615 1.0 0.3220907426665014 2 Q96CW5 1 +Gamma tubulin complex 0.8212996389891682 1.9214486289068131 0.0546751728631615 1.0 0.3220907426665014 2 Q96CW5 1 +Respirasome 0.4764630017762742 1.9030509063233016 0.0570339030354998 1.0 0.3285314976489964 40 P13073,O75306,P09669,Q9Y276,P51970,Q9UDW1,O75489,P15954,P14927,Q86Y39,O43676,Q16795,Q16718,Q9NX14,O14949 15 +Mitochondrial intermembrane space protein transporter complex 0.8061371841155216 1.8524588006595024 0.063959968418191 1.0 0.3553775745235741 2 Q9Y5L4 1 +Cytosolic region 0.8172601754479466 1.8393033917566324 0.0658705744633572 1.0 0.3619396513731189 6 Q9UQB8 1 +Actin filament 0.5221452389777135 1.8231673996579931 0.0682780409694565 1.0 0.3656577013364269 30 Q6IBS0,Q14195,Q7KZI7,P35609,Q96EY1 5 +Rough endoplasmic reticulum 0.5067893331645532 1.792630444765002 0.0730320349915079 1.0 0.3841744325884646 32 Q9UQB8,P61353,O95793,P30533,Q96A33,P04844 6 +Platelet dense granule lumen 0.7844765342960267 1.753374448565323 0.0795377539541704 1.0 0.4110992050305667 2 Q08380 1 +Envelope 0.309465143051487 1.714356196210946 0.0864633281656661 1.0 0.4370464102315444 424 Q13505,O60830,Q99595,P80303,P00846,Q14728,Q9NS69,O75844,P22570,O75027,Q9NRX2,Q8NE86,Q69YU5,Q9BQT8,Q9UDW1,O75489,Q7Z7K6,Q70HW3,Q15070,Q9H1E5,O43169,O15173,O43676,P09601,Q9UI26,Q9BVC6,Q9Y3B8,Q5HYI7,O95674,Q13057,Q9C0E2,P14927,Q9NVI7,Q9Y5L4,Q6P1L8,Q6P4A7,Q5JTV8,Q9Y2R5,Q86Y39,Q96T37,Q96TA2,Q9NX14,Q9Y584,Q13084,O14925,Q9BYD2,Q9NQ50,P56385,Q8WUX9,Q96RL7,O94901,O95202,Q6PI78,Q9Y276,Q9BQ95,Q96DV4,Q9Y3D9,P82664,Q9BWH2,Q9H2D1,Q5SRE5,Q9UBX3,Q9BX68,Q9UDX5,Q8NE71,P23786,O95140,P09669,Q9Y2Q9,O43592,O15294,Q8NBU5,Q6NUM9,Q9NRK6,Q5VT66,P52294,P57105,O75608,P36551,P51970,Q9Y2R0,Q5XKP0,O14949,O15397,P13073 85 +Exocyst 0.7920089695891341 1.6591945225782798 0.0970766009929091 1.0 0.4609953035273035 5 Q96KP1,Q96A65 2 +Picln sm protein complex 0.7890022390308153 1.6473248536515182 0.0994912920219639 1.0 0.4623734376359275 5 P54105 1 +Polymeric cytoskeletal fiber 0.3356704064949978 1.645531850347009 0.0998601800068594 1.0 0.4623734376359275 154 P68371,Q9UQB8,P04350,Q02241,Q7KZI7,P29372,P07196,P36507,P35609,Q6IBS0,Q12756,Q12792,Q8WWK9,Q99661,Q9P253,O43237,Q96EY1,P00568,Q8IZT6,P50748,Q9H0H5,Q00839,O43663,Q8WUX9,P07197,Q14195,O43633,P14923,Q9BSJ2,Q96CW5,P58107,O00139,P16949,P15924 34 +Methyltransferase complex 0.4865890836383275 1.6393278703871308 0.101144994650556 1.0 0.4658958561883126 32 Q9UJA5,P54105,Q03164,Q96T37 4 +Cytochrome complex 0.5709748387577787 1.6363274816104014 0.1017710674652958 1.0 0.4663632936940619 16 P09669,Q9UDW1,Q9Y276,P14927,O14949 5 +Cis golgi network 0.691396591402068 1.6184280471294532 0.1055703816654505 1.0 0.47614301640041 9 Q14789,Q9NPR9,O00461 3 +Chromosome centromeric region 0.3713788147829636 1.5899176328924658 0.1118533724937278 1.0 0.4922655848857626 85 Q9UER7,P14635,Q53HL2,Q14141,P62805,Q96ST3,Q99661,O43237,Q9BZD4,Q2NKX8,Q9NTI5,Q9HBM1,P50748,Q7Z7K6,Q9BPX3,Q00839,Q8WUX9,P42695,Q7Z5K2,Q8IWS0,P46100 21 +Proton transporting atp synthase complex 0.6392462523255287 1.5786214775121488 0.1144229053114231 1.0 0.4937959360284233 11 P00846 1 +Proton transporting atp synthase complex coupling factor f o 0.7207182597934627 1.5468549054223302 0.1218982370426426 1.0 0.5135902025161581 7 P00846 1 +Extrinsic component of plasma membrane 0.4735578398616974 1.5397516623794787 0.1236208985547848 1.0 0.5159576470197359 32 P31749,P14923,Q08209,Q9H0H5,P04899,Q96EY1 6 +Presynaptic cytosol 0.9035600325660844 1.5269529937836943 0.1267727005077592 1.0 0.5241903755878975 3 Q9UQB8 1 +Lamellipodium 0.4201377801866844 1.5052492078479722 0.1322600182911433 1.0 0.5309522496871184 53 Q9UQB8,Q6IBS0,Q14195,Q9UHY1,P31749,P11940 6 +Nuclear inner membrane 0.5219497823404307 1.4747858480056029 0.140270127154493 1.0 0.5566970671443943 19 Q5JTV8,Q14728,Q9H1E5,O75844 4 +Extrinsic component of cytoplasmic side of plasma membrane 0.5329131168165482 1.4551481037314993 0.1456282643990101 1.0 0.5655154869056009 17 P04899,Q9H0H5,P31749 3 +Golgi associated vesicle membrane 0.5169830371467938 1.4442613161522155 0.1486654828701421 1.0 0.5717246631608506 19 Q8IUH4 1 +Rna polymerase i complex 0.6943543178678883 1.4350973076658002 0.1512593706689644 1.0 0.5739200235372933 7 O15160,P19388,Q9H9Y6 3 +Neuron to neuron synapse 0.4113820633224045 1.4335135047884144 0.1517111423298807 1.0 0.5739200235372933 54 Q9UQB8,Q9Y639 2 +Clathrin coated pit 0.5261894024174533 1.4155564902138216 0.1569053979129209 1.0 0.5860878098512046 17 O94973,Q01968,Q8NC96 3 +Cell body 0.3554527403820709 1.4027472465795627 0.1606922230041032 1.0 0.592223931169497 89 Q9UQB8,Q14195,Q8TEY7,O95793,P78310,P42574,P04899,Q9P265,P20339 9 +Cytoplasmic side of endoplasmic reticulum membrane 0.686336669993575 1.401004211706954 0.1612128136591881 1.0 0.592223931169497 7 Q8TCT8 1 +Adherens junction 0.4250116606940549 1.3885013445106025 0.1649844356390355 1.0 0.6008023810589942 37 Q9UQB8,P26038,P78310 3 +Somatodendritic compartment 0.3505150497695959 1.38435010919436 0.1662512775483831 1.0 0.6008023810589942 123 Q9UQB8,Q7KZI7,O95793,Q9Y639,P04899,Q9P265,Q8N2K0 7 +Spindle midzone 0.5229736110496628 1.3603439239937716 0.1737211147416766 1.0 0.6078246477779208 16 Q13432,Q53HL2,Q7Z7K6 3 +Distal axon 0.4096556289857628 1.3547109431131648 0.1755096699737635 1.0 0.6078246477779208 48 Q6IBS0,Q14195,Q14141,P78310,P07196,P20339,P80723,Q96A65 8 +Golgi lumen 0.8566269411339811 1.3540659541323103 0.1757153368716824 1.0 0.6078246477779208 3 Q9NX62,O00461 2 +Rna polymerase complex 0.4644134602096672 1.3429546951805302 0.179286644188986 1.0 0.6153892922162493 28 O15160,P19388,Q9H9Y6,O95602,Q9NQG5,P18074 6 +Escrt complex 0.7114635350576319 1.33855151114806 0.1807167204508712 1.0 0.616008649808874 5 Q8WUX9,Q92783,O43633 3 +Cytosolic small ribosomal subunit 0.4519319577207223 1.3381334659611943 0.1808529331834827 1.0 0.616008649808874 31 P46781,P62841,P62244,P62269,P39019,P62263,P62081,P15880,P61247,P08865,P62277,Q7Z478,P62249,P62241,P62753 15 +Neurofilament 0.8473014282157356 1.319687338094947 0.1869394292367276 1.0 0.6271288777035884 3 P07196 1 +Nadh dehydrogenase complex 0.4804941813601597 1.3097645989724611 0.1902754825123271 1.0 0.6292093080471318 21 O75306,P56556,P51970,O75489,P19404,O43676,Q86Y39,O95182,Q16795,O75251,Q16718,Q9NX14 12 +Ribosomal subunit 0.3490984929685065 1.3093895874879424 0.1904024167604245 1.0 0.6292093080471318 114 P62906,Q96DV4,P47914,P18077,Q6P1L8,P52815,P62249,P62910,Q9Y3U8,P62899,Q9Y2R5,P62753,P62424,P82664,P49406,P62841,Q9NRX2,P32969,P63173,P62263,P62081,P15880,P30050,Q92552,Q9BRJ2,P82673,P62241,Q9H9J2,Q13084,Q8N5N7,P35268,P82675,P62244,P62829,P62269,Q9BYD2,P39019,Q14197,P62750,P61247,P08865,Q9NQ50,Q7Z478,P62277,P05388,P46781,P61353,P42766,P18124,P26373,Q9Y2Q9,P05387,P51116 53 +Proton transporting two sector atpase complex catalytic domain 0.582509130930093 1.2993759719752804 0.1938149335414378 1.0 0.6334613085233024 11 P21281,P21283,P06576,P36543 4 +Outer membrane 0.3574114242111681 1.283833468978468 0.1992002301861952 1.0 0.6435936042975055 80 Q13505,O43169,P09601,Q9BVC6,Q9NS69,Q5HYI7 6 +Proton transporting two sector atpase complex 0.4742134079910078 1.2820674054026209 0.1998190017721022 1.0 0.6435936042975055 22 P21281,P00846 2 +Respiratory chain complex iii 0.6358644237941032 1.280029417584334 0.2005347900904488 1.0 0.6435936042975055 8 P14927,Q9UDW1,Q9Y276 3 +Cytosolic large ribosomal subunit 0.4018564938522442 1.2689370204375925 0.2044635272551291 1.0 0.6475449763698312 46 P62906,P47914,P18077,P62910,Q9Y3U8,P62899,P62424,P32969,P63173,P30050,P35268,P62829,P62750,P05388,P46779,P61353,P42766,P18124,P26373,P05387,P51116 21 +Fascia adherens 0.6938040205274822 1.2677912868071797 0.204872494596791 1.0 0.6475449763698312 5 P14923 1 +Ragulator complex 0.677978339350177 1.260873888015592 0.2073542873830336 1.0 0.6513708886343353 2 Q6IAA8 1 +Neuron projection cytoplasm 0.4354307753375964 1.2466463095161815 0.2125272134937099 1.0 0.6531395011605621 32 Q9UQB8,P07196,Q8N2K0 3 +Microtubule associated complex 0.4006422560276203 1.2438194155008304 0.213566032999243 1.0 0.6531395011605621 43 Q02241,Q53HL2,Q12756,O95793,P49356,Q99661,Q96S59,O43237,O00139,Q9Y3P9 10 +Specific granule membrane 0.5306114764733237 1.238288956578385 0.2156089371306702 1.0 0.6531395011605621 13 O15126,P30519,Q08722,Q14165,Q8NHP6,Q6IAA8,O00161 7 +Aryl hydrocarbon receptor complex 0.6685920577617293 1.2174603476929664 0.2234291143140621 1.0 0.6531395011605621 2 P08238 1 +Neuron projection 0.3116464480152028 1.1987158763989647 0.2306384425452057 1.0 0.6531395011605621 183 Q9UQB8,Q7KZI7,Q9H2U1,P78310,P07196,Q08209,O76024,P58546,P35609,P04899,Q9P265,P52294,Q6IBS0,Q4V328,Q14141,Q12756,O95793,Q9Y639,P04792,Q96A65,Q8N2K0,Q01968,P20339,P07197,Q14195,Q8TAG9,O14745,P80723,O00161,P16949 30 +Endoplasmic reticulum quality control compartment 0.676544928874788 1.19863127102537 0.2306713532264048 1.0 0.6531395011605621 5 Q9BUN8 1 +Specific granule lumen 0.5428418307670103 1.1984243146977909 0.2307518713265868 1.0 0.6531395011605621 12 P14923,O00764 2 +Gamma secretase complex 0.66425992779783 1.1974508131500885 0.2311308882571094 1.0 0.6531395011605621 2 Q92542 1 +Transporter complex 0.3924720507744512 1.1948079528534743 0.2321620724035293 1.0 0.6531395011605621 48 Q9UDW1,Q9C0H2,O75489,P14927,Q86Y39,O43676,Q8NE86,Q9Y5L4,Q8N2K0 9 +Anchored component of membrane 0.6367578900388282 1.1896759853820331 0.2341737676277062 1.0 0.6546555956636191 7 P36551,P20339 2 +Microvillus membrane 0.7931419872921714 1.1819275536161942 0.237234447938766 1.0 0.6590669506798844 4 P26038 1 +Small ribosomal subunit 0.3902657930437534 1.1578123458147322 0.2469406240862044 1.0 0.679660107779058 45 P62841,P82675,P62244,P62753,P62269,P39019,P62263,P62081,P15880,P61247,Q7Z478,Q9Y2Q9,P82673,P82664,P62249,P62241,Q9Y2R5 17 +Core mediator complex 0.7998738801651287 1.145263259983481 0.2521001203514177 1.0 0.6841497746992625 3 Q71SY5 1 +Clathrin vesicle coat 0.569410760715316 1.1436636377841407 0.2527631589074586 1.0 0.6841497746992625 10 O94973,Q8NC96 2 +Clathrin coated vesicle membrane 0.4527496285671495 1.1413806168015763 0.2537115672449519 1.0 0.6841497746992625 22 O94973,P20339,Q8NC96,P20645 4 +Supramolecular polymer 0.3102895837461352 1.1390844644666658 0.2546679265582079 1.0 0.6841497746992625 193 P68371,Q9UQB8,P04350,Q02241,Q7KZI7,P29372,P07196,Q08209,P36507,P35609,Q6IBS0,Q12756,Q12792,Q8WWK9,Q9Y376,Q9P253,Q99661,O43237,P04792,Q96EY1,P00568,Q8IZT6,P50748,O75190,Q9H0H5,Q00839,O43663,Q8WUX9,P07197,Q14195,O43633,P14923,Q9BSJ2,P16949,Q96CW5,P58107,O00139,Q9UNE7,P35659,P15924 40 +Emc complex 0.643869107423682 1.1318039101961113 0.2577168834525118 1.0 0.6841497746992625 6 Q8N4V1 1 +Pseudopodium 0.6006879588763794 1.1245323299048182 0.2607872631509798 1.0 0.689999633753634 8 P35609 1 +Membrane microdomain 0.3777989013847204 1.1185478853703517 0.2633330669906715 1.0 0.6911633888741664 55 P09601,Q8WTV0,P04899,P20339,O14773 5 +Anchored component of synaptic vesicle membrane 0.6535332358676985 1.106575429314027 0.2684775353359279 1.0 0.6930139119149201 5 P20339 1 +Proteasome regulatory particle base subcomplex 0.5786585206863046 1.1036185909268563 0.2697586232017084 1.0 0.6931081388043895 9 P55036,Q13200,P62333 3 +Proton transporting two sector atpase complex proton transporting domain 0.5599127096905506 1.0985958073184174 0.2719444073068917 1.0 0.6967105996997889 10 P00846 1 +Platelet dense granule 0.7847598410978549 1.0899932914470656 0.2757160992027296 1.0 0.7023255363645463 3 O15439,Q08380 2 +Condensed chromosome centromeric region 0.3605639230454049 1.078543586064762 0.2807912415941023 1.0 0.7096122786556167 64 Q8WUX9,Q9HBM1,P42695,Q14141,P50748,Q96ST3,Q99661,Q7Z7K6,O43237,Q9BZD4,Q8IWS0,Q2NKX8,Q9BPX3,P46100,Q00839,P14635 16 +Midbody 0.3418310630351737 1.076352684080488 0.2817695549667409 1.0 0.7096122786556167 79 Q96KP1,Q8WUX9,Q53HL2,Q02241,Q14141,O43633,Q8IZT6,Q53EZ4,Q7Z7K6,Q9NQW6,Q9H0H5,Q8TAG9,Q9BPX3,Q00839,P04899,Q96A65,O43663 17 +Oligosaccharyltransferase complex 0.6036482161137646 1.0488798213095112 0.2942334337923964 1.0 0.7286170547115332 7 P04843,Q8TCJ2,P04844 3 +Specific granule 0.4193137984815568 1.040979831168998 0.2978849089065867 1.0 0.731261374815853 29 O15126,O00764,P14923,P30519,Q6IAA8,O00161,Q9BS26 7 +Clathrin coated endocytic vesicle membrane 0.4936799499518812 1.0402690039263651 0.2982149405312455 1.0 0.731261374815853 13 P20339,P20645 2 +Retromer complex 0.5805006424723913 1.0356487895148263 0.3003660215043133 1.0 0.7335862448278422 8 Q13596 1 +Oxidoreductase complex 0.3709234820676166 1.0317069966160224 0.3022093987865317 1.0 0.7360661795102101 53 O43169,O75306,Q9Y276,P51970,Q9UDW1,O75489,P14927,Q86Y39,O43676,Q16795,O75251,Q16718,Q9NX14,Q5VT66,O14949 15 +Neuron spine 0.412620028741478 1.015545957618006 0.3098456509684322 1.0 0.7444669830025303 30 Q9UQB8 1 +Intrinsic component of endoplasmic reticulum membrane 0.3726296748124747 1.0112330417874902 0.3119049048656328 1.0 0.7473007909080095 48 O75844,Q92643,Q8TB61,Q9Y282,Q8N4V1,Q86XL3,Q8TCT8,O76024,Q9BUN8,Q96A33,Q9NPA0,O00767,O95470,Q16799 14 +Proton transporting v type atpase v1 domain 0.5914011436000082 0.9970886806607706 0.3187214668503539 1.0 0.747733891438502 7 P21281,P21283 2 +Intrinsic component of golgi membrane 0.5552422698070889 0.9969779951568252 0.3187751910632084 1.0 0.747733891438502 9 Q9Y282 1 +Methylosome 0.5540236009667526 0.9914513645523744 0.3214652296922269 1.0 0.7500855359485294 9 P54105 1 +Alpha dna polymerase primase complex 0.6230630624479363 0.98537951640615 0.3244376873398185 1.0 0.7520145662106542 5 Q14181,P49642,P09884 3 +Intercellular bridge 0.4293760009760808 0.9797680758564404 0.3272006138248648 1.0 0.7537201184665522 21 Q53HL2,Q7Z5K2,Q53EZ4,Q9H7N4,Q13432 5 +Synaptic vesicle membrane 0.4640390305532541 0.9796436435319514 0.3272620536873893 1.0 0.7537201184665522 14 O43760,O76024,P20339,P20337 4 +Caveola 0.4789105074571332 0.9616503987502084 0.3362252459664132 1.0 0.7695570977558469 13 Q8WTV0 1 +Intrinsic component of presynaptic membrane 0.7313405679451506 0.9571993996233285 0.3384666200478472 1.0 0.7695570977558469 4 Q9Y639 1 +Postsynaptic endosome 0.7446590448373503 0.944776983915902 0.3447727446552187 1.0 0.7756301372152358 3 P20339 1 +Neuromuscular junction 0.4555482706477257 0.932562840194648 0.3510457270839549 1.0 0.7756301372152358 14 P07196,Q96EY1 2 +Mitochondrion 0.2881527659684268 0.9314760601987676 0.3516073625396401 1.0 0.7756301372152358 542 Q13505,O95674,Q13057,O60830,O95202,Q6PI78,Q9Y276,Q99595,Q7KZI7,Q9NUJ1,Q9H2U1,Q9BQ95,Q16822,Q9Y237,Q15165,P14927,Q9NVI7,Q9Y5P4,Q9HC38,Q9HCC0,Q9Y5L4,Q6P1L8,Q6P4A7,P00846,Q08209,P36507,P82664,Q9NS69,P14635,Q9Y2R5,P18858,P22570,O75027,Q9NRX2,Q86Y39,Q8NE86,Q69YU5,Q96TA2,Q5TC12,Q9BQT8,Q9NX14,Q9Y584,Q5JPH6,Q96DV4,Q96EY1,Q13084,O14925,Q9UDW1,P31749,O75489,Q9BYD2,Q70HW3,Q9Y2W6,Q04837,Q9NQ50,Q15070,Q9Y3D9,P56385,Q9UII2,O43169,Q7L592,P13051,P00374,O43676,P09601,Q9Y3E5,Q96RL7,Q9Y3B8,Q5HYI7 69 +Cornified envelope 0.6039986327919369 0.9102571710180593 0.362686899809332 1.0 0.7853623870296551 5 P14923 1 +Commitment complex 0.6020021587768882 0.90243276216173 0.3668270239818274 1.0 0.7877034403860981 5 P62316,P62314,P62318 3 +Vesicle tethering complex 0.4413704825476094 0.8902723481931332 0.3733196651275556 1.0 0.7958781350081463 16 Q96KP1,Q9P253,Q8TAG9,Q8IUR0,Q96A65 5 +Plasma membrane raft 0.4349285870800442 0.8789020289902423 0.3794543984565943 1.0 0.802715906518228 17 Q8WTV0 1 +Side of membrane 0.3388421815374777 0.8764811823061865 0.3807685019280815 1.0 0.802715906518228 66 O15439,P61353,P31749,P14923,Q8TCT8,Q08209,Q9H0H5,P36507,P04899,P20339 10 +Chromosomal region 0.2960895261468098 0.8693208788558122 0.3846716459805241 1.0 0.8084470290228983 149 Q9H2U1,O94761,Q9UBD5,Q9UER7,P14635,Q53HL2,Q14141,P62805,Q96ST3,Q9UBB9,Q99661,O43237,Q9BZD4,Q2NKX8,Q9P0M6,Q9NTI5,Q9HBM1,P50748,Q7Z7K6,Q9BPX3,Q00839,O94842,Q8WUX9,P42695,Q7Z5K2,P05455,Q8IWS0,P46100 28 +Site of polarized growth 0.3570993943164263 0.8544145183269153 0.3928753544490793 1.0 0.816042500245868 40 Q14195,Q6IBS0,P78310,P07196,P80723,Q96A65 6 +Ubiquitin conjugating enzyme complex 0.7015480493558162 0.8510286412553615 0.3947534428449448 1.0 0.8180321927486153 4 Q9UNE7,P61088 2 +Proteasome regulatory particle 0.4246288632835799 0.8464981279399083 0.3972749177609991 1.0 0.8210214352141654 18 O00487 1 +Large ribosomal subunit 0.3324526802147692 0.833004976990925 0.4048419223601371 1.0 0.8210214352141654 69 P62906,Q96DV4,P47914,P18077,Q6P1L8,P52815,P62910,Q9Y3U8,P62899,P49406,P62424,Q9NRX2,P63173,P32969,P30050,Q9BRJ2,Q9H9J2,Q13084,Q8N5N7,P35268,Q9BYD2,Q14197,P62750,Q9NQ50,P05388,P61353,P42766,P18124,P26373,P05387,P51116 31 +Mcrd mediated mrna stability complex 0.5824782814076076 0.8264421567307221 0.4085533177352896 1.0 0.8210214352141654 5 Q9H074 1 +Clathrin complex 0.5815884476534248 0.8231785557540258 0.4104064616747593 1.0 0.8210214352141654 2 P09496 1 +Early endosome membrane 0.3697443520206446 0.8044800958087582 0.4211197600308674 1.0 0.8337983667426305 34 Q4V328,Q01968,Q13596,Q8N4V1,Q92783,P20339 6 +Contractile ring 0.6866863073839347 0.7988883327701303 0.424355164732507 1.0 0.8383372032159971 4 Q9NQW6 1 +Eukaryotic translation initiation factor 3 complex 0.430541676356337 0.7955968732050069 0.4262663845804948 1.0 0.8386984125812457 14 O00303,Q14152,Q7L2H7 3 +Cortical endoplasmic reticulum 0.5732851985559515 0.786933496162985 0.4313207979038405 1.0 0.8438458912789575 2 P50402 1 +Plasma membrane region 0.2831043864911108 0.7764436744534907 0.4374870657507079 1.0 0.8456420209555218 166 Q9UQB8,Q8NBU5,Q53EZ4,P78310,P33527,Q8WTV0,Q14728,P57105,Q8TAD4,P36551,Q14141,Q12792,Q9Y639,Q92542,P26038,Q96EY1,Q9H4M9,P21281,Q01968,Q8IZT6,Q9NWH9,P31751,Q9H0H5,Q8NC96,O15439,O95721,O94973,Q99797,P14923,P09601,Q9NVZ3,O14745,P58107,P15924 34 +Respiratory chain complex iv 0.4895824765387476 0.7704549652305019 0.4410300593596665 1.0 0.8456420209555218 10 P13073,P09669,P47985,P15954,P00403 5 +Gtpase complex 0.554287954022381 0.7698119241880471 0.4414114653620662 1.0 0.8456420209555218 6 P04899 1 +Proton transporting atp synthase complex catalytic core f 1 0.6775142891120496 0.7670420004095078 0.4430565442204428 1.0 0.8456420209555218 4 P06576 1 +Synaptic membrane 0.3513829060149734 0.7656561621135889 0.4438809176846456 1.0 0.8456420209555218 37 Q9UQB8,Q9Y639 2 +Ciliary base 0.5515307117519923 0.7590009289073444 0.4478520011164302 1.0 0.848012823264342 6 P17612,A0AVF1 2 +Vcp npl4 ufd1 aaa atpase complex 0.5514836114674689 0.7588165083144153 0.447962328968392 1.0 0.848012823264342 6 Q92890,Q04323 2 +Endocytic vesicle membrane 0.3627492058502377 0.7508142761655462 0.4527644364612153 1.0 0.8484948721155502 34 P20339,Q01968,Q8WTV0,P20645 4 +Translation preinitiation complex 0.4193466148430109 0.7502109284117418 0.4531276779219704 1.0 0.8484948721155502 15 Q7Z478,O00303,Q14152,Q7L2H7 4 +Microvillus 0.4078804625287758 0.7489841737783375 0.4538667443659123 1.0 0.8484948721155502 18 P21281,P26038,Q96A65 3 +Desmosome 0.5613298702094832 0.7454460376930179 0.4560021214873764 1.0 0.8484948721155502 5 P14923 1 +Nurf complex 0.6875787819760515 0.7441283645317468 0.4567988207980464 1.0 0.8484948721155502 3 P28370 1 +Ribosome 0.3015387097575293 0.7349554063557953 0.4623666529962444 1.0 0.8527882873727414 131 P62906,Q96DV4,P47914,P18077,Q6P1L8,P52815,P62249,P62910,Q9Y3U8,P62899,Q9Y2R5,P62753,P62424,P82664,P49406,P62841,Q9NRX2,P32969,P63173,P62263,P62081,P15880,P30050,Q92552,Q9BRJ2,P82673,P62241,Q9P2E9,Q13084,Q9H9J2,Q8N5N7,P35268,P82675,P62244,P62829,P62269,Q9BYD2,P39019,Q14197,P62750,P61247,O95182,P08865,Q9NQ50,Q7Z478,P62277,P05388,P46781,P61353,P42766,P18124,P26373,Q9Y2Q9,P05387,P51116 55 +Ruffle 0.3384275063477979 0.7275914464741174 0.466863718166016 1.0 0.8557563823702851 53 Q9UQB8,P20936,P21281,P53365,P20339 5 +Actin cytoskeleton 0.3045640091643395 0.7224929792145238 0.4699914402961154 1.0 0.8579515203762763 122 Q8N5W9,Q9UQB8,Q14195,Q6IBS0,Q7KZI7,P14923,Q9P253,Q9NQW6,P07305,P58546,P35609,P20339,Q96EY1 13 +Eukaryotic translation initiation factor 3 complex eif3m 0.5058997918438666 0.7149787131969553 0.4746221968215196 1.0 0.8638994496868265 8 O00303,Q7L2H7 2 +Supramolecular complex 0.2685066283589271 0.7140548138385723 0.4751932855982657 1.0 0.8638994496868265 321 P68371,Q9UQB8,Q02241,P04350,Q8WX93,Q7KZI7,Q9H2U1,P29372,Q13283,P07196,Q08209,P11940,P36507,P35609,Q9H6S0,P82979,P14635,P62753,A5YKK6,Q6IBS0,Q14141,O60828,Q12756,O95793,Q12792,Q96ST3,Q9Y376,Q8WWK9,Q9P253,Q99661,O43237,P04792,Q9BZD4,Q2NKX8,Q96EY1,Q9HBM1,P00568,Q8IZT6,P50748,Q7Z7K6,Q14671,Q9Y2W6,O75190,Q9H0H5,Q92797,Q00839,O43663,Q8WUX9,P07197,Q14195,O75116,O43633,P14923,Q96F86,Q9Y333,Q8IWS0,P16949,Q96CW5,P58107,Q9BSJ2,O00139,P51116,P08579,Q9UNE7,P35659,P15924 66 +Cell division site 0.3856433350784902 0.7102432164506827 0.4775533256791415 1.0 0.8664181765892996 22 Q14141,Q53EZ4,Q9UHB6,Q9UHD8,P35241,Q9NQW6,Q9BSJ2,Q9H0H5,Q96CW5 9 +Clathrin coated endocytic vesicle 0.4036859615180535 0.7013340859748541 0.4830945464073375 1.0 0.8703253199509959 17 P20339,P20645 2 +Mitotic spindle midzone 0.5490868076022498 0.6993390204100044 0.4843401868798236 1.0 0.8703253199509959 5 Q00839 1 +Golgi associated vesicle 0.3718859110913734 0.6906938787438267 0.4897579369387537 1.0 0.87083777899754 28 Q8IUH4,Q8TCT8 2 +Voltage gated calcium channel complex 0.550541516245482 0.6896782802696952 0.4903965275385009 1.0 0.87083777899754 2 P62942 1 +Dna packaging complex 0.37944267123879 0.6874727081522825 0.4917848933413415 1.0 0.87083777899754 24 P42695,P10412,P62805,P16403,P16104,Q92522,P07305,Q9BPX3,O95347,Q9NTJ3,Q9P0M6 11 +Myosin filament 0.5480144404332075 0.6790800354432587 0.497087151572597 1.0 0.8750702529664134 2 P35579 1 +Camp dependent protein kinase complex 0.665583243048026 0.6697236790838118 0.5030339539711708 1.0 0.8817172279536537 3 P17612,P10644 2 +Prefoldin complex 0.6320119295848023 0.6137983194359358 0.5393486079326177 1.0 0.9135502455709904 4 Q99471,O15212 2 +Cytoplasmic dynein complex 0.4973122670631859 0.6132718599928647 0.5396965967288083 1.0 0.9135502455709904 7 O43237,Q14204,Q9Y6G9,Q9UJW0 4 +Carboxy terminal domain protein kinase complex 0.6467581612438449 0.6077747873742708 0.5433368533976588 1.0 0.9135502455709904 3 Q14004 1 +Pericentric heterochromatin 0.4526226666006041 0.6064144909270541 0.5442395482584181 1.0 0.9135502455709904 10 P42695 1 +Clathrin coated vesicle 0.3257897099419885 0.5926489530578772 0.5534161105823547 1.0 0.9230523870688806 40 Q01968,Q9NVZ3,P20645,Q8NC96,O94973,P20339 6 +Insulin responsive compartment 0.5220216606498137 0.5729600436674464 0.5666717481918049 1.0 0.9363776656924064 2 P61026 1 +Kinesin complex 0.3983522662065696 0.5513270006733317 0.5814095324550457 1.0 0.9501343278539258 13 O00139,Q02241,Q12756 3 +Proteasome accessory complex 0.3561980688974885 0.5298304109242502 0.596229518190525 1.0 0.9638085540838454 21 P55036,P62333,O00487 3 +Stereocilium bundle 0.4905007976360535 0.5294283311067995 0.5965083491245669 1.0 0.9638085540838454 6 Q14651,Q6IBS0,O14745 3 +Organellar ribosome 0.3209188329895764 0.5250003417592383 0.5995829533578299 1.0 0.9638865199549924 37 P82675,Q9BYD2,Q96DV4,Q9NRX2,Q9Y2Q9,Q9NQ50,Q6P1L8,P82664,Q9Y2R5,Q13084 10 +Spindle 0.2856187757579903 0.5142027332681354 0.607110257000997 1.0 0.9644815170786318 131 Q02241,Q9Y237,P14635,Q53HL2,Q14141,Q8WWK9,Q99661,P04792,Q13432,P18074,Q8IZT6,P31749,P50748,Q16539,Q7Z7K6,Q9H0H5,Q99986,Q9BPX3,Q00839,O43663,Q8WUX9,Q7Z5K2,O43633,Q9BSJ2,Q96CW5,O00139 26 +Intrinsic component of synaptic vesicle membrane 0.4173272578308447 0.5125723904930298 0.6082504704212515 1.0 0.9644815170786318 11 O76024,P20339,P20337 3 +Elongin complex 0.6123485008285354 0.4996054469888483 0.6173529217195313 1.0 0.9644815170786318 3 Q14241 1 +Mitochondrial large ribosomal subunit 0.3493471526333259 0.4974565834967863 0.6188671122763125 1.0 0.9644815170786318 23 Q9BYD2,Q9NRX2,Q9NQ50,Q6P1L8,Q13084 5 +Trans golgi network membrane 0.3458305809629706 0.4772382372315344 0.6331924857566196 1.0 0.9644815170786318 23 P53365,Q10567,Q9NX62,P20645 4 +Rna polymerase ii transcription regulator complex 0.3451447430194624 0.4733226685099734 0.6359829918772137 1.0 0.9644815170786318 23 O75448,Q13951,P40763,Q71SY5,P17096 5 +Nuclear outer membrane 0.432727193195408 0.472436648881274 0.6366151503689708 1.0 0.9644815170786318 9 Q9BVC6,Q9NXE4,Q6NUM9 3 +Spindle pole 0.3106543813752766 0.4716192586134802 0.6371985778118712 1.0 0.9644815170786318 49 O00139,Q8IZT6,P50748,Q16539,Q8WWK9,Q96CW5,Q00839,Q13432,P14635,O43663 10 +Chaperone complex 0.3446926562031688 0.4707466614880499 0.6378216584204457 1.0 0.9644815170786318 23 O95456 1 +Azurophil granule membrane 0.3599611671418472 0.468539136790258 0.6393990902563513 1.0 0.9644815170786318 17 Q92542,Q6IAA8,P42785,O95721,O15260 5 +Dendritic growth cone 0.6016612495485725 0.4675665433609609 0.6400945951365498 1.0 0.9644815170786318 3 P07900,P08238 2 +Dendrite terminus 0.6016612495485725 0.4675665433609609 0.6400945951365498 1.0 0.9644815170786318 3 P07900,P08238 2 +Apicolateral plasma membrane 0.4825369551016464 0.4633050714119582 0.6431457111743974 1.0 0.9658049615439852 5 P14923,P78310 2 +F actin capping protein complex 0.4799993091132357 0.4549332067458057 0.6491572922618334 1.0 0.968289987954312 5 P58546 1 +Blood microparticle 0.3584303179134435 0.4474104622486122 0.6545787231837625 1.0 0.9736029496374192 16 P26038,Q4V328,P02786 3 +Clathrin coat 0.3622958496809835 0.4469522725272813 0.654909520678489 1.0 0.9736029496374192 14 O94973,Q8NC96 2 +Postsynapse 0.2843113020206422 0.4437515843744899 0.657222195924315 1.0 0.9754099034669717 110 P57105,Q9UQB8,Q4V328,Q8NBU5,P31749,P62269,P39019,Q9Y639,P07196,Q01469,Q08209,P35609,P51608,P20339,P52294,Q96EY1 16 +Secretory granule membrane 0.2978777795012314 0.4353688937567983 0.6632946852394483 1.0 0.9763792788927574 62 Q8TAD4,P15924,Q12756,P84095,P30519,Q92542,Q01469,Q6IAA8,P42785,O00161,O15439,O95721,O94973,O15260,P10253 15 +Golgi apparatus 0.2737899837965112 0.4301104720403014 0.6671152827326896 1.0 0.9786559180682526 250 Q9UQB8,Q8TEY7,Q8NBN3,Q9NY61,Q8IUH4,P80303,Q969S3,Q9Y5P4,O95197,P07305,O00461,P36507,Q8IWJ2,Q9NX62,Q9NPR9,O14773,Q15392,Q8TAD4,Q14004,Q8N4V1,P20645,O95456,Q01968,Q10567,P60520,P53365,Q8TB61,Q7Z5K2,Q9Y282,Q14789,Q96RL7 31 +Mitochondrial small ribosomal subunit 0.3709474318619836 0.4254459347759525 0.6705116263535624 1.0 0.9817848405621178 13 P82664,Q9Y2R5,Q9Y2Q9 3 +Sperm midpiece 0.4691564618077968 0.4198063849158826 0.6746269001728027 1.0 0.982788949965194 5 Q96RL7 1 +Cyclin dependent protein kinase holoenzyme complex 0.4168273051907324 0.412632631875837 0.679875789456327 1.0 0.9840864440721648 9 P14635 1 +Ficolin 1 rich granule membrane 0.3480249355605255 0.4098013793573384 0.6819516542954018 1.0 0.9840864440721648 17 P10253,Q6IAA8,P42785,O94973,P15924 5 +Beta catenin destruction complex 0.5785482123510297 0.4012066666933349 0.6882679728226264 1.0 0.9840864440721648 3 Q9HB71,P35222 2 +Apical plasma membrane 0.3003624575531299 0.3971725651727731 0.6912402117250951 1.0 0.9840864440721648 40 Q8TAD4,Q8IZT6,P26038,P33527,O15439 5 +Paranodal junction 0.4729241877256253 0.3908718008682504 0.6958919987577916 1.0 0.9840864440721648 2 Q8IXJ6 1 +Endoplasmic reticulum golgi intermediate compartment 0.2983962384719815 0.380418678434721 0.7036346516318046 1.0 0.9852009795555594 41 Q9BS26,Q9Y282,Q14789,P80303,P30533,Q8IUR0,Q9NYU2,O15498 8 +Transferase complex transferring phosphorus containing groups 0.2921426775659565 0.3779878037006816 0.7054396542692285 1.0 0.9852009795555594 61 Q14004,P19388,Q9H9Y6,Q9Y376,Q9NQG5,P14635,Q07864 7 +Lipid droplet 0.3159055268999534 0.367960243856477 0.712902878444807 1.0 0.9897639165988856 31 P09455,O43760,Q96RL7 3 +Nucleotide activated protein kinase complex 0.5495453256821681 0.3660456427026786 0.7143310175348483 1.0 0.9897639165988856 4 P10644,P54619 2 +Proteasome complex 0.2970158018923027 0.3639692281612459 0.7158809880462131 1.0 0.9897639165988856 46 P55036,O75832,O00487,P49721,P04792,O43396 6 +Amphisome 0.5616221310065779 0.3554158970248774 0.722278041185273 1.0 0.9955119048274536 3 Q8WUX9 1 +Amphisome membrane 0.5616221310065779 0.3554158970248774 0.722278041185273 1.0 0.9955119048274536 3 Q8WUX9 1 +Aminoacyl trna synthetase multienzyme complex 0.3748641796450567 0.342167875775123 0.7322245591411627 1.0 0.9999302223602948 11 P54136,P41252,Q13155,P47897,P56192,Q12904,P14868,Q15046,P07814,Q9P2J5 10 +Intercalated disc 0.3610984129727808 0.3338048451639259 0.73852682702924 1.0 0.9999302223602948 12 P14923,Q6PI78,P15924 3 +Endopeptidase complex 0.2915952457285296 0.328082833549027 0.7428490331354212 1.0 0.9999302223602948 51 P55036,O75832,Q92643,O00487,P49721,P04792,O43396 7 +Post mrna release spliceosomal complex 0.399849854181805 0.3178195799126286 0.7506217975626768 1.0 0.9999302223602948 8 Q9UBB9,P16383 2 +Mitochondrial proton transporting atp synthase complex coupling factor f o 0.4341747917054236 0.3144718320016025 0.7531627069100975 1.0 0.9999302223602948 5 P56385 1 +Transferase complex 0.2567400520029111 0.2947193987178396 0.7682082430115806 1.0 1.0 178 Q8TEY7,Q03164,P19388,Q9H9Y6,P14635,P54105,O75448,P49356,Q14004,Q9Y376,O60762,Q96T37,P04844,O43318,Q16763,Q8TCJ2,Q9BUN8,P61088,Q07864,Q9NQG5,Q9UJA5,Q9UNE7,O15294,Q9NXV2,P62314 25 +Trapp complex 0.5368055929786593 0.2930674882435087 0.7694705668604085 1.0 1.0 3 Q8IUR0 1 +Heterochromatin 0.3056778951849722 0.2927706305017329 0.76969747854712 1.0 1.0 29 P42695,Q9NZM5,P46100,P51608,P17096 5 +Ap type membrane coat adaptor complex 0.3744825007755764 0.269398895990181 0.7876227356412984 1.0 1.0 9 O94973 1 +Multivesicular body membrane 0.5099577777479354 0.266949586299198 0.7895079771417322 1.0 1.0 4 Q8WUX9,O43633 2 +Cytoplasmic region 0.2809538979944147 0.2578630455084698 0.79651260596789 1.0 1.0 54 Q9UQB8,P04792,P07196,Q8N2K0 4 +Cd40 receptor complex 0.4263537906137122 0.2481635314295602 0.8040078815937217 1.0 1.0 2 Q9NR28 1 +Extrinsic component of organelle membrane 0.3473557626860032 0.2466819979907835 0.8051543396149374 1.0 1.0 11 Q4V328 1 +Proteasome core complex beta subunit complex 0.3865912168329387 0.2421884519005822 0.8086341427849364 1.0 1.0 7 P49721 1 +I band 0.2932663323555529 0.2407688119892242 0.8097343030440982 1.0 1.0 31 P14923,Q9Y376,O75190,P04792,P35609,Q9UNE7 6 +Origin recognition complex 0.4037319408894414 0.2343912796987068 0.8146812279056022 1.0 1.0 5 Q9UBD5 1 +Extrinsic component of mitochondrial inner membrane 0.4198555956678638 0.231037638564994 0.8172855615805992 1.0 1.0 2 Q96BW9 1 +Nuclear inclusion body 0.3696624528596056 0.228802800055054 0.8190221903882162 1.0 1.0 8 Q9UNE7 1 +Sarcoplasm 0.3053726052639972 0.2243438186749965 0.8224897826450752 1.0 1.0 17 Q9BVC6 1 +Axon 0.2619058467117998 0.2182114284371702 0.8272643810292153 1.0 1.0 102 Q14195,Q6IBS0,Q4V328,Q14141,Q9H2U1,P78310,Q9Y639,P07196,P20339,P04792,P80723,P58546,Q9P265,Q96A65 14 +Tertiary granule membrane 0.3511635096694891 0.2024734184421935 0.8395466370567535 1.0 1.0 9 P10253,Q9Y2Q5,Q08722,O00161 4 +Golgi stack 0.2905375035876494 0.1985973038219748 0.8425777628406572 1.0 1.0 23 Q14789,Q8NBN3,O00461 3 +Microtubule 0.2609912509943564 0.1930068725980731 0.8469535857356862 1.0 1.0 109 P68371,Q9UQB8,Q02241,P36507,Q12756,Q8WWK9,Q99661,O43237,Q8IZT6,P50748,Q9H0H5,Q00839,O43663,Q8WUX9,O43633,Q9BSJ2,Q96CW5,O00139,P16949,P29372 20 +Cytoplasmic ubiquitin ligase complex 0.3436249760615205 0.1828900481166739 0.8548842916488448 1.0 1.0 9 Q9BUN8 1 +Condensed chromosome 0.2542979788735952 0.182717037119159 0.8550200471171912 1.0 1.0 93 Q8WUX9,Q9HBM1,P42695,Q7Z5K2,Q14141,P50748,Q96ST3,Q7Z7K6,Q99661,O43237,Q9BZD4,Q8IWS0,Q2NKX8,Q9BPX3,P46100,Q00839,P14635 17 +Immunological synapse 0.2953133228996954 0.1801957516272237 0.8569988935534667 1.0 1.0 15 P20020,Q9Y639,P52565,Q8WUM4,O95999,Q96L92,P10644,Q9UJZ1 8 +Septin cytoskeleton 0.3787793426569537 0.1779813235389526 0.858737643212528 1.0 1.0 5 Q9UHD8,Q14141 2 +Peptidase complex 0.2677524686810885 0.1741706099837799 0.8617313823220716 1.0 1.0 56 P55036,O75832,Q92643,O00487,P49721,P28072,P67812,P04792,O43396 9 +Protein phosphatase 4 complex 0.3920577617328463 0.1661782892877008 0.8680166445180475 1.0 1.0 2 Q8TF05 1 +Scf ubiquitin ligase complex 0.3647866955892861 0.1636665994631513 0.8699936126977432 1.0 1.0 6 Q9HB71,Q13616,P63208,Q93034,Q13617 5 +Mediator complex 0.3534709508449289 0.1619718735405557 0.8713280030320805 1.0 1.0 7 Q71SY5 1 +Phosphatase complex 0.2884781850050564 0.1582266849521568 0.8742781770607386 1.0 1.0 15 Q08209,O94842,Q9UQ13 3 +Kinetochore microtubule 0.3612133894799193 0.15634565946147 0.8757605677801981 1.0 1.0 6 Q8WUX9,P50748 2 +Organelle subcompartment 0.2433991648777974 0.1558973430444343 0.876113939646741 1.0 1.0 317 O95674,Q8NBN3,Q6NUM9,P67812,P53367,Q9Y5P4,O95197,P08240,O76024,O00461,Q16850,Q8IWJ2,Q9NX62,Q9NPR9,Q9BS26,O75844,Q15392,Q92643,O75915,Q8N4V1,Q8TCT8,Q15800,O60762,P20645,P04844,Q96HY6,Q5JRA6,Q8N2K0,Q96G23,Q01968,Q06136,Q9NZ08,Q10567,Q8TCJ2,Q99640,Q9BUN8,Q96A33,Q99986,Q9NPA0,P60520,P53365,O00767,Q8TB61,P61353,Q9Y282,Q14789,P51648,P30519,P09601,Q96RL7,Q9BVC6,Q04323,O95470 53 +U12 type spliceosomal complex 0.2975325573474929 0.1545449040957094 0.8771801081304589 1.0 1.0 13 Q15427 1 +Endocytic vesicle lumen 0.3575560375994088 0.1490565768474334 0.8815089896853352 1.0 1.0 6 P27797,P14625,O14964,P07900,Q92598 5 +Magnesium dependent protein serine threonine phosphatase complex 0.3332125962341841 0.141159442012811 0.8877439857681197 1.0 1.0 8 Q08209 1 +Mmxd complex 0.4591185539349025 0.1403301639953166 0.8883991326995586 1.0 1.0 3 P18074 1 +Apical part of cell 0.2617033891127927 0.1328003426664416 0.8943512833518064 1.0 1.0 49 P21281,Q8TAD4,P36551,Q8IZT6,Q99797,P21283,Q99808,P26038,P33527,O14745,O15439,P08195 12 +B wich complex 0.3317644973889251 0.1190725987774047 0.9052178392793064 1.0 1.0 7 P35659 1 +Rough endoplasmic reticulum membrane 0.274462438758286 0.1164332862355183 0.9073091561847448 1.0 1.0 14 Q96A33 1 +Spectrin 0.4281069364161919 0.1159903180428106 0.907660215084698 1.0 1.0 4 O43491,Q13813,O15020 3 +U1 snrnp 0.2983064727538106 0.1136647914258114 0.9095035239567686 1.0 1.0 11 P09012,P08579,P62314,P62318 4 +Vesicle membrane 0.2504512320648041 0.1041938368454253 0.9170155248370736 1.0 1.0 211 P84095,Q8IUH4,O43760,O76024,Q6IAA8,O00461,Q8WTV0,Q14728,Q92783,Q8TAD4,Q4V328,Q13596,Q12756,Q8N4V1,Q9P253,Q92542,Q8TCT8,P20645,O15498,Q9H4M9,O43318,Q01968,Q15750,Q10567,Q01469,P42785,Q8NC96,O15439,O95721,O94973,P20339,O15260,O75436,Q8WUX9,O43633,P20337,P61923,P30519,Q9NVZ3,Q96T51,Q96RL7,Q9P2R3,O00161,Q96L92,P15924 45 +Polysomal ribosome 0.2634884465930899 0.0978486606966225 0.9220524670953434 1.0 1.0 26 Q9Y3U8 1 +Dynein complex 0.3023124945880097 0.0945713890841135 0.9246552761574652 1.0 1.0 9 O43237,Q14204,Q9Y6G9,Q9UJW0 4 +Dynactin complex 0.3241778099024142 0.0860174356671731 0.931452556938292 1.0 1.0 5 Q9NZ32,P61163,Q9UJW0,Q13561 4 +Cleavage furrow 0.2618285748633254 0.0856002852663368 0.9317841716838338 1.0 1.0 17 Q9H0H5,Q14141 2 +Proton transporting v type atpase complex 0.2815251299779983 0.0802139993306669 0.9360670561846194 1.0 1.0 11 P21281,P21283 2 +Chromatoid body 0.3382671480144341 0.0797718280060532 0.9364187308933348 1.0 1.0 2 P06730 1 +Intermediate filament cytoskeleton 0.256796187844666 0.0780672124833641 0.937774588219266 1.0 1.0 30 O75832,Q9UHR5,P14923,P07196,P58107,P15924 6 +Cell leading edge 0.2448013026458262 0.0690267936139887 0.9449682921399896 1.0 1.0 102 Q9UQB8,P21281,P20936,Q9UHY1,Q14195,Q6IBS0,P31749,P31751,P11940,P53365,P20339 11 +Gap junction 0.38381030811537 0.0663816009111874 0.9470740182355022 1.0 1.0 4 Q99797 1 +Multivesicular body 0.2800942163973372 0.0604765732785628 0.9517760735069788 1.0 1.0 9 Q8WUX9,O14964,O43633,P10644 4 +Endoplasmic reticulum 0.2417515594133277 0.0602614658965505 0.9519473919031034 1.0 1.0 414 P55145,Q9UQB8,O95674,Q9Y680,Q6NUM9,Q8TED0,Q8IUH4,P80303,P67812,P30533,Q9Y5P4,O95197,P08240,O76024,Q8NBJ5,P36507,O95302,Q16850,Q9BRR6,Q9H6S0,Q9BS26,O75844,Q15392,Q92643,O75915,O75608,O95793,Q8N4V1,Q8NBQ5,Q92542,Q8TCT8,P84157,Q13217,Q15800,O60762,Q9H0P0,P04844,Q96HY6,Q5JRA6,Q16799,O95456,Q8N2K0,O15498,Q96G23,Q06136,Q9NZ08,Q8TCJ2,Q99640,Q9BUN8,Q96A33,Q9NPA0,P60520,O00767,Q9NYU2,Q8TB61,O15173,P61353,Q9Y282,P51648,Q99797,P30519,P09601,Q96RL7,Q9BVC6,Q8IUR0,Q04323,O95470,Q9UNE7 68 +Cell cell junction 0.2394190175610776 0.0531011734502647 0.9576512964957112 1.0 1.0 95 Q9UQB8,Q6PI78,P31749,P14923,P78310,Q08209,P26038,P58107,P15924 9 +U2 snrnp 0.2440451645536708 0.0476586769656079 0.96198826766007 1.0 1.0 16 O43719,P08579,P62314,Q15428 4 +Smc5 smc6 complex 0.3647526182737418 0.0451127294983202 0.9640174550809142 1.0 1.0 3 Q96SB8,Q8IY18 2 +Protein dna complex 0.2434627137311305 0.0409446683120949 0.9673400071219768 1.0 1.0 51 P10412,P16403,Q9BRX5,P14923,P07305,P35244,Q9UBD5,Q9P0M6 8 +Trans golgi network transport vesicle membrane 0.3475433526011607 0.0406498219131825 0.9675750648124096 1.0 1.0 4 O95782,P09496,Q00610 3 +Spindle microtubule 0.2428582847216802 0.0366256135878589 0.9707835205384354 1.0 1.0 25 Q8WUX9,O43633,O00139,P50748,Q96CW5,Q00839,O43663 7 +Male germ cell nucleus 0.2605710155402964 0.030225008792422 0.9758876035082312 1.0 1.0 5 P16104,Q15645,P54652,P62826 4 +Germ cell nucleus 0.260665220535057 0.0286520596205929 0.9771420915335204 1.0 1.0 6 P29966,P16104,P62826,Q15645,P54652 5 +Mitochondrial pyruvate dehydrogenase complex 0.3200867052023188 0.0283522529613521 0.9773812054926794 1.0 1.0 4 P11177,P10515,P09622 3 +Phagocytic cup 0.3164739884393107 0.0271122416447625 0.978370210930002 1.0 1.0 4 Q9Y5X3,P50570,P04083 3 +Protein phosphatase type 2a complex 0.2508131550415614 0.0256055994353775 0.9795719198320998 1.0 1.0 5 P63151,Q15257,Q14738,P30153 4 +Eukaryotic translation initiation factor 4f complex 0.2513562386980064 0.0253650808242258 0.9797637636064324 1.0 1.0 7 P60842,P23588,Q15056,Q04637,P06730,O43432 6 +Nuclear stress granule 0.3045108956812772 0.023771803997778 0.981034630842028 1.0 1.0 3 Q92797 1 +Elongator holoenzyme complex 0.3028116353572966 0.0230981621477316 0.9815719716898972 1.0 1.0 4 Q6IA86,Q96EB1 2 +Granular component 0.2929913294797742 0.0208031793367571 0.9834026615448634 1.0 1.0 4 O75683,P22087,Q9NXV6 3 +Cul5 ring ubiquitin ligase complex 0.282773564463699 0.0204256273753168 0.9837038404236818 1.0 1.0 3 Q15369,Q93034 2 +Transcription elongation factor complex 0.2299298124740136 0.018217915861057 0.9854650102178192 1.0 1.0 18 Q6IA86,Q8WX92,Q14004,Q14241 4 +Cul2 ring ubiquitin ligase complex 0.2773251139908629 0.0179966331113096 0.9856415393650771 1.0 1.0 4 Q15369 1 diff --git a/msigdb_gocc/selections.json b/msigdb_gocc/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..2a1196213adc4c9367718e17e26d4ad36e21d60a --- /dev/null +++ b/msigdb_gocc/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["90s preribosome", "9plus0 non motile cilium", "9plus2 motile cilium", "A band", "Acrosomal membrane", "Acrosomal vesicle", "Actin based cell projection", "Actin cytoskeleton", "Actin filament", "Actin filament bundle", "Actomyosin", "Adherens junction", "Aggresome", "Alpha dna polymerase primase complex", "Alveolar lamellar body", "Aminoacyl trna synthetase multienzyme complex", "Ampa glutamate receptor complex", "Amphisome", "Amphisome membrane", "Anaphase promoting complex", "Anchored component of membrane", "Anchored component of plasma membrane", "Anchored component of postsynaptic membrane", "Anchored component of synaptic membrane", "Anchored component of synaptic vesicle membrane", "Anchoring junction", "Annulate lamellae", "Ap 1 adaptor complex", "Ap 3 adaptor complex", "Ap type membrane coat adaptor complex", "Apical dendrite", "Apical junction complex", "Apical part of cell", "Apical plasma membrane", "Apicolateral plasma membrane", "Arp2 3 protein complex", "Aryl hydrocarbon receptor complex", "Aster", "Astrocyte end foot", "Astrocyte projection", "Atac complex", "Atpase complex", "Atpase dependent transmembrane transport complex", "Autolysosome", "Autophagosome", "Autophagosome membrane", "Axolemma", "Axon", "Axon cytoplasm", "Axon hillock", "Axon initial segment", "Axonal growth cone", "Azurophil granule", "Azurophil granule lumen", "Azurophil granule membrane", "B wich complex", "Barr body", "Basal cortex", "Basal dendrite", "Basal part of cell", "Basement membrane", "Basolateral plasma membrane", "Bcl 2 family protein complex", "Beta catenin destruction complex", "Beta catenin tcf complex", "Bleb", "Bloc complex", "Blood microparticle", "Box c d rnp complex", "Box h aca rnp complex", "Box h aca snornp complex", "Box h aca telomerase rnp complex", "Brca1 a complex", "Brca1 c complex", "Brisc complex", "Brush border", "Brush border membrane", "Cajal body", "Calcineurin complex", "Calcium channel complex", "Camp dependent protein kinase complex", "Carboxy terminal domain protein kinase complex", "Caspase complex", "Catalytic complex", "Catalytic step 1 spliceosome", "Catalytic step 2 spliceosome", "Catenin complex", "Cation channel complex", "Cation transporting atpase complex", "Catsper complex", "Caveola", "Cbm complex", "Ccaat binding factor complex", "Ccr4 not complex", "Ccr4 not core complex", "Cd40 receptor complex", "Cd95 death inducing signaling complex", "Cdc73 paf1 complex", "Cell body", "Cell body membrane", "Cell cell contact zone", "Cell cell junction", "Cell cortex", "Cell cortex region", "Cell division site", "Cell leading edge", "Cell pole", "Cell projection membrane", "Cell substrate junction", "Cell surface", "Cell tip", "Cell trailing edge", "Central element", "Centriolar satellite", "Centriolar subdistal appendage", "Centriole", "Centrosome", "Cerebellar mossy fiber", "Chaperone complex", "Chaperonin containing t complex", "Chitosome", "Chloride channel complex", "Cholinergic synapse", "Chromaffin granule", "Chromaffin granule membrane", "Chromatin", "Chromatin silencing complex", "Chromatoid body", "Chromocenter", "Chromosomal region", "Chromosome", "Chromosome centromeric core domain", "Chromosome centromeric region", "Chromosome passenger complex", "Chromosome telomeric region", "Chromosome telomeric repeat region", "Cia complex", "Ciliary basal body", "Ciliary base", "Ciliary membrane", "Ciliary plasm", "Ciliary rootlet", "Ciliary tip", "Ciliary transition zone", "Cilium", "Cis golgi network", "Cis golgi network membrane", "Clathrin adaptor complex", "Clathrin coat", "Clathrin coat of coated pit", "Clathrin coat of endocytic vesicle", "Clathrin coated endocytic vesicle", "Clathrin coated endocytic vesicle membrane", "Clathrin coated pit", "Clathrin coated vesicle", "Clathrin coated vesicle membrane", "Clathrin complex", "Clathrin sculpted gamma aminobutyric acid transport vesicle", "Clathrin sculpted vesicle", "Clathrin vesicle coat", "Cleavage furrow", "Cluster of actin based cell projections", "Coated vesicle", "Coated vesicle membrane", "Cohesin complex", "Collagen containing extracellular matrix", "Collagen trimer", "Commitment complex", "Compact myelin", "Condensed chromosome", "Condensed chromosome centromeric region", "Condensed nuclear chromosome", "Condensin complex", "Contractile fiber", "Contractile ring", "Cop9 signalosome", "Copi coated vesicle", "Copi coated vesicle membrane", "Copi vesicle coat", "Copii coated er to golgi transport vesicle", "Copii vesicle coat", "Core mediator complex", "Cornified envelope", "Cortical actin cytoskeleton", "Cortical cytoskeleton", "Cortical endoplasmic reticulum", "Cortical granule", "Costamere", "Crd mediated mrna stability complex", "Ctf18 rfc like complex", "Cul2 ring ubiquitin ligase complex", "Cul3 ring ubiquitin ligase complex", "Cul4 ring e3 ubiquitin ligase complex", "Cul4a ring e3 ubiquitin ligase complex", "Cul4b ring e3 ubiquitin ligase complex", "Cul5 ring ubiquitin ligase complex", "Cullin ring ubiquitin ligase complex", "Cuticular plate", "Cyclin a2 cdk2 complex", "Cyclin cdk positive transcription elongation factor complex", "Cyclin dependent protein kinase holoenzyme complex", "Cytochrome complex", "Cytolytic granule", "Cytoplasmic dynein complex", "Cytoplasmic exosome rnase complex", "Cytoplasmic microtubule", "Cytoplasmic region", "Cytoplasmic side of endoplasmic reticulum membrane", "Cytoplasmic side of endosome membrane", "Cytoplasmic side of lysosomal membrane", "Cytoplasmic side of membrane", "Cytoplasmic stress granule", "Cytoplasmic ubiquitin ligase complex", "Cytoskeleton of presynaptic active zone", "Cytosolic large ribosomal subunit", "Cytosolic region", "Cytosolic ribosome", "Cytosolic small ribosomal subunit", "Death inducing signaling complex", "Dendrite cytoplasm", "Dendrite membrane", "Dendrite terminus", "Dendritic growth cone", "Dendritic shaft", "Dendritic spine membrane", "Dendritic tree", "Dense body", "Dense core granule", "Dense core granule membrane", "Dentate gyrus mossy fiber", "Derlin 1 retrotranslocation complex", "Desmosome", "Dihydrolipoyl dehydrogenase complex", "Distal axon", "Dna packaging complex", "Dna polymerase complex", "Dna repair complex", "Dna replication factor c complex", "Dna replication preinitiation complex", "Dopaminergic synapse", "Dynactin complex", "Dynein axonemal particle", "Dynein complex", "Dystrophin associated glycoprotein complex", "Early endosome", "Early endosome lumen", "Early endosome membrane", "Early phagosome", "Ekc keops complex", "Elongator holoenzyme complex", "Elongin complex", "Emc complex", "Endocytic vesicle", "Endocytic vesicle lumen", "Endocytic vesicle membrane", "Endolysosome", "Endolysosome lumen", "Endolysosome membrane", "Endopeptidase complex", "Endoplasmic reticulum", "Endoplasmic reticulum chaperone complex", "Endoplasmic reticulum exit site", "Endoplasmic reticulum golgi intermediate compartment", "Endoplasmic reticulum golgi intermediate compartment membrane", "Endoplasmic reticulum lumen", "Endoplasmic reticulum palmitoyltransferase complex", "Endoplasmic reticulum plasma membrane contact site", "Endoplasmic reticulum protein containing complex", "Endoplasmic reticulum quality control compartment", "Endoplasmic reticulum tubular network", "Endoplasmic reticulum tubular network membrane", "Endoribonuclease complex", "Endosome", "Endosome lumen", "Endosome membrane", "Envelope", "Enzyme activator complex", "Epsilon dna polymerase complex", "Equatorial microtubule organizing center", "Er membrane insertion complex", "Er to golgi transport vesicle membrane", "Er ubiquitin ligase complex", "Esc e z complex", "Escrt complex", "Escrt i complex", "Escrt iii complex", "Euchromatin", "Eukaryotic translation initiation factor 2 complex", "Eukaryotic translation initiation factor 2b complex", "Eukaryotic translation initiation factor 3 complex", "Eukaryotic translation initiation factor 3 complex eif3m", "Eukaryotic translation initiation factor 4f complex", "Excitatory synapse", "Exocyst", "Exocytic vesicle", "Exon exon junction complex", "Exoribonuclease complex", "External encapsulating structure", "External side of apical plasma membrane", "External side of plasma membrane", "Extrinsic component of cytoplasmic side of plasma membrane", "Extrinsic component of endoplasmic reticulum membrane", "Extrinsic component of endosome membrane", "Extrinsic component of external side of plasma membrane", "Extrinsic component of membrane", "Extrinsic component of mitochondrial inner membrane", "Extrinsic component of organelle membrane", "Extrinsic component of plasma membrane", "Extrinsic component of postsynaptic membrane", "Extrinsic component of postsynaptic specialization membrane", "Extrinsic component of synaptic membrane", "F actin capping protein complex", "Fascia adherens", "Female germ cell nucleus", "Female pronucleus", "Fibrillar center", "Ficolin 1 rich granule", "Ficolin 1 rich granule lumen", "Ficolin 1 rich granule membrane", "Filamentous actin", "Filopodium", "Filopodium membrane", "Filopodium tip", "Filtration diaphragm", "Flemming body", "Flotillin complex", "Gaba ergic synapse", "Gamma secretase complex", "Gamma tubulin complex", "Gap junction", "Gator2 complex", "Gemini of coiled bodies", "Germ cell nucleus", "Glial cell projection", "Glutamatergic synapse", "Glycinergic synapse", "Glycogen granule", "Glycoprotein complex", "Golgi apparatus", "Golgi apparatus subcompartment", "Golgi associated vesicle", "Golgi associated vesicle membrane", "Golgi cis cisterna", "Golgi cisterna", "Golgi cisterna membrane", "Golgi lumen", "Golgi medial cisterna", "Golgi membrane", "Golgi stack", "Golgi trans cisterna", "Golgi transport complex", "Gpi anchor transamidase complex", "Granular component", "Growth cone membrane", "Gtpase complex", "Guanyl nucleotide exchange factor complex", "H3 histone acetyltransferase complex", "H4 h2a histone acetyltransferase complex", "H4 histone acetyltransferase complex", "Haus complex", "Hemidesmosome", "Hemoglobin complex", "Heterochromatin", "Hfe transferrin receptor complex", "High density lipoprotein particle", "Hippocampal mossy fiber", "Hippocampal mossy fiber to ca3 synapse", "Histone deacetylase complex", "Histone methyltransferase complex", "Histone pre mrna 3 end processing complex", "Hops complex", "Host cellular component", "Hrd1p ubiquitin ligase erad l complex", "Hulc complex", "I band", "Ikappab kinase complex", "Immunological synapse", "Inclusion body", "Inflammasome complex", "Inhibitory synapse", "Inner mitochondrial membrane protein complex", "Ino80 complex", "Ino80 type complex", "Insulin responsive compartment", "Integral component of cytoplasmic side of endoplasmic reticulum membrane", "Integral component of lysosomal membrane", "Integral component of presynaptic active zone membrane", "Integral component of synaptic vesicle membrane", "Integrator complex", "Integrin complex", "Intercalated disc", "Intercellular bridge", "Intercellular canaliculus", "Intermediate filament", "Intermediate filament cytoskeleton", "Intracellular protein containing complex", "Intraciliary transport particle", "Intraciliary transport particle b", "Intrinsic component of endoplasmic reticulum membrane", "Intrinsic component of golgi membrane", "Intrinsic component of mitochondrial inner membrane", "Intrinsic component of mitochondrial membrane", "Intrinsic component of mitochondrial outer membrane", "Intrinsic component of nuclear inner membrane", "Intrinsic component of organelle membrane", "Intrinsic component of peroxisomal membrane", "Intrinsic component of plasma membrane", "Intrinsic component of postsynaptic density membrane", "Intrinsic component of postsynaptic membrane", "Intrinsic component of postsynaptic specialization membrane", "Intrinsic component of presynaptic active zone membrane", "Intrinsic component of presynaptic membrane", "Intrinsic component of synaptic membrane", "Intrinsic component of synaptic vesicle membrane", "Intrinsic component of vacuolar membrane", "Ion channel complex", "Iron sulfur cluster assembly complex", "Iswi type complex", "Juxtaparanode region of axon", "Keratin filament", "Kinesin complex", "Kinetochore microtubule", "Lamellar body", "Lamellipodium", "Lamellipodium membrane", "Lamin filament", "Large ribosomal subunit", "Late endosome", "Late endosome membrane", "Lateral element", "Lateral part of cell", "Lateral plasma membrane", "Leading edge membrane", "Lewy body", "Lipid droplet", "Lipopolysaccharide receptor complex", "Lsm1 7 pat1 complex", "Lsm2 8 complex", "Lumenal side of endoplasmic reticulum membrane", "Lumenal side of membrane", "Lysosomal lumen", "M band", "Magnesium dependent protein serine threonine phosphatase complex", "Main axon", "Male germ cell nucleus", "Male pronucleus", "Manchette", "Mcm complex", "Mcrd mediated mrna stability complex", "Mediator complex", "Meiotic cohesin complex", "Meiotic spindle", "Membrane coat", "Membrane microdomain", "Membrane protein complex", "Messenger ribonucleoprotein complex", "Methylosome", "Methyltransferase complex", "Mhc class i peptide loading complex", "Mhc class i protein complex", "Mhc protein complex", "Mib complex", "Micos complex", "Microbody", "Microbody lumen", "Microbody membrane", "Microtubule", "Microtubule associated complex", "Microtubule bundle", "Microtubule cytoskeleton", "Microtubule end", "Microtubule minus end", "Microtubule organizing center", "Microtubule organizing center attachment site", "Microtubule plus end", "Microvillus", "Microvillus membrane", "Midbody", "Mismatch repair complex", "Mitochondria associated endoplasmic reticulum membrane", "Mitochondrial alpha ketoglutarate dehydrogenase complex", "Mitochondrial crista", "Mitochondrial envelope", "Mitochondrial intermembrane space protein transporter complex", "Mitochondrial large ribosomal subunit", "Mitochondrial matrix", "Mitochondrial permeability transition pore complex", "Mitochondrial protein containing complex", "Mitochondrial proton transporting atp synthase complex coupling factor f o", "Mitochondrial pyruvate dehydrogenase complex", "Mitochondrial small ribosomal subunit", "Mitochondrial tricarboxylic acid cycle enzyme complex", "Mitochondrion", "Mitotic cohesin complex", "Mitotic spindle", "Mitotic spindle astral microtubule", "Mitotic spindle microtubule", "Mitotic spindle midzone", "Mitotic spindle pole", "Mll1 2 complex", "Mll3 4 complex", "Mmxd complex", "Motile cilium", "Mpp7 dlg1 lin7 complex", "Mrna cleavage and polyadenylation specificity factor complex", "Mrna cleavage factor complex", "Mrna editing complex", "Multimeric ribonuclease p complex", "Multivesicular body", "Multivesicular body membrane", "Myelin sheath", "Myelin sheath abaxonal region", "Myelin sheath adaxonal region", "Myofilament", "Myosin complex", "Myosin filament", "Myosin ii complex", "N terminal protein acetyltransferase complex", "Nadh dehydrogenase complex", "Nascent polypeptide associated complex", "Nata complex", "Nbaf complex", "Neurofibrillary tangle", "Neurofilament", "Neuromuscular junction", "Neuron projection", "Neuron projection cytoplasm", "Neuron projection membrane", "Neuron projection terminus", "Neuron spine", "Neuron to neuron synapse", "Neuronal dense core vesicle", "Neuronal dense core vesicle membrane", "Neuronal ribonucleoprotein granule", "Neurotransmitter receptor complex", "Nlrp3 inflammasome complex", "Nls dependent protein nuclear import complex", "Node of ranvier", "Non motile cilium", "Nonhomologous end joining complex", "Npbaf complex", "Nsl complex", "Nuclear body", "Nuclear chromosome", "Nuclear cyclin dependent protein kinase holoenzyme complex", "Nuclear envelope", "Nuclear envelope lumen", "Nuclear exosome rnase complex", "Nuclear inclusion body", "Nuclear inner membrane", "Nuclear lamina", "Nuclear membrane", "Nuclear outer membrane", "Nuclear outer membrane endoplasmic reticulum membrane network", "Nuclear periphery", "Nuclear pore", "Nuclear pore central transport channel", "Nuclear pore nuclear basket", "Nuclear pore outer ring", "Nuclear protein containing complex", "Nuclear replication fork", "Nuclear rna export factor complex", "Nuclear speck", "Nuclear stress granule", "Nuclear ubiquitin ligase complex", "Nucleocytoplasmic transport complex", "Nucleoid", "Nucleolar ribonuclease p complex", "Nucleolus", "Nucleotide activated protein kinase complex", "Nucleotide excision repair complex", "Nurd complex", "Nurf complex", "Oligosaccharyltransferase complex", "Organellar ribosome", "Organelle envelope lumen", "Organelle inner membrane", "Organelle membrane contact site", "Organelle subcompartment", "Origin recognition complex", "Outer dense fiber", "Outer kinetochore", "Outer membrane", "Outer mitochondrial membrane protein complex", "Oxidoreductase complex", "Oxoglutarate dehydrogenase complex", "P body", "Palmitoyltransferase complex", "Pam complex tim23 associated import motor", "Parallel fiber to purkinje cell synapse", "Paranodal junction", "Paranode region of axon", "Paraspeckles", "Pcg protein complex", "Peptidase complex", "Peptidase inhibitor complex", "Pericentric heterochromatin", "Pericentriolar material", "Periciliary membrane compartment", "Perikaryon", "Perinuclear endoplasmic reticulum", "Perinuclear region of cytoplasm", "Perinucleolar compartment", "Phagocytic cup", "Phagocytic vesicle", "Phagocytic vesicle lumen", "Phagocytic vesicle membrane", "Phagolysosome", "Phagophore assembly site", "Phagophore assembly site membrane", "Phosphatase complex", "Phosphatidylinositol 3 kinase complex", "Phosphatidylinositol 3 kinase complex class iii", "Photoreceptor connecting cilium", "Photoreceptor inner segment", "Photoreceptor outer segment", "Photoreceptor ribbon synapse", "Pi body", "Picln sm protein complex", "Pigment granule", "Pinosome", "Pip body", "Plasma membrane protein complex", "Plasma membrane raft", "Plasma membrane region", "Plasma membrane signaling receptor complex", "Platelet alpha granule", "Platelet alpha granule lumen", "Platelet dense granule", "Platelet dense granule lumen", "Platelet dense granule membrane", "Platelet dense tubular network", "Platelet dense tubular network membrane", "Pml body", "Podosome", "Polar microtubule", "Pole plasm", "Polymeric cytoskeletal fiber", "Polysomal ribosome", "Polysome", "Pore complex", "Post mrna release spliceosomal complex", "Postsynapse", "Postsynaptic cytoskeleton", "Postsynaptic cytosol", "Postsynaptic density intracellular component", "Postsynaptic density membrane", "Postsynaptic endocytic zone", "Postsynaptic endosome", "Postsynaptic membrane", "Postsynaptic recycling endosome", "Postsynaptic specialization intracellular component", "Postsynaptic specialization membrane", "Pre snornp complex", "Precatalytic spliceosome", "Prefoldin complex", "Preribosome", "Preribosome large subunit precursor", "Preribosome small subunit precursor", "Prespliceosome", "Presynapse", "Presynaptic active zone", "Presynaptic active zone cytoplasmic component", "Presynaptic active zone membrane", "Presynaptic cytoskeleton", "Presynaptic cytosol", "Presynaptic endocytic zone", "Presynaptic membrane", "Pronucleus", "Protease inhibitor complex", "Proteasome accessory complex", "Proteasome complex", "Proteasome core complex", "Proteasome core complex alpha subunit complex", "Proteasome core complex beta subunit complex", "Proteasome regulatory particle", "Proteasome regulatory particle base subcomplex", "Proteasome regulatory particle lid subcomplex", "Protein acetyltransferase complex", "Protein complex involved in cell adhesion", "Protein dna complex", "Protein kinase complex", "Protein lipid complex", "Protein phosphatase 4 complex", "Protein phosphatase type 1 complex", "Protein phosphatase type 2a complex", "Proton transporting atp synthase complex", "Proton transporting atp synthase complex catalytic core f 1", "Proton transporting atp synthase complex coupling factor f o", "Proton transporting two sector atpase complex", "Proton transporting two sector atpase complex catalytic domain", "Proton transporting two sector atpase complex proton transporting domain", "Proton transporting v type atpase complex", "Proton transporting v type atpase v0 domain", "Proton transporting v type atpase v1 domain", "Proximal dendrite", "Prp19 complex", "Pseudopodium", "Ptw pp1 phosphatase complex", "Pwp2p containing subcomplex of 90s preribosome", "R2tp complex", "Ragulator complex", "Rdna heterochromatin", "Receptor complex", "Recycling endosome", "Recycling endosome membrane", "Replication fork", "Replisome", "Respirasome", "Respiratory chain complex iii", "Respiratory chain complex iv", "Retromer complex", "Ribbon synapse", "Ribonuclease mrp complex", "Ribonuclease p complex", "Ribonucleoprotein complex", "Ribonucleoprotein granule", "Ribose phosphate diphosphokinase complex", "Ribosomal subunit", "Ribosome", "Risc loading complex", "Rna cap binding complex", "Rna polymerase complex", "Rna polymerase i complex", "Rna polymerase ii core complex", "Rna polymerase ii holoenzyme", "Rna polymerase ii transcription regulator complex", "Rna polymerase ii transcription repressor complex", "Rna polymerase iii complex", "Rna polymerase iii transcription regulator complex", "Rnai effector complex", "Rough endoplasmic reticulum", "Rough endoplasmic reticulum membrane", "Rpap3 r2tp prefoldin like complex", "Ruffle", "Ruffle membrane", "Saga complex", "Saga type complex", "Sarcolemma", "Sarcoplasm", "Sarcoplasmic reticulum lumen", "Sarcoplasmic reticulum membrane", "Scar complex", "Scf ubiquitin ligase complex", "Schaffer collateral ca1 synapse", "Schmidt lanterman incisure", "Sec61 translocon complex", "Secondary lysosome", "Secretory granule", "Secretory granule membrane", "Secretory vesicle", "Seh1 associated complex", "Septin cytoskeleton", "Serine protease inhibitor complex", "Set1c compass complex", "Sex chromatin", "Sex chromosome", "Shelterin complex", "Side of membrane", "Signal peptidase complex", "Signal recognition particle", "Sin3 complex", "Sin3 type complex", "Site of dna damage", "Site of double strand break", "Site of polarized growth", "Sm like protein family complex", "Small ribosomal subunit", "Small subunit processome", "Smc5 smc6 complex", "Smn complex", "Smn sm protein complex", "Smooth endoplasmic reticulum", "Smooth endoplasmic reticulum membrane", "Snare complex", "Sno s rna containing ribonucleoprotein complex", "Sodium potassium exchanging atpase complex", "Somatodendritic compartment", "Sorting endosome", "Spanning component of membrane", "Specific granule", "Specific granule lumen", "Specific granule membrane", "Spectrin", "Spectrin associated cytoskeleton", "Sperm annulus", "Sperm connecting piece", "Sperm fibrous sheath", "Sperm head", "Sperm head plasma membrane", "Sperm midpiece", "Sperm plasma membrane", "Sperm principal piece", "Spermatoproteasome complex", "Spindle", "Spindle microtubule", "Spindle midzone", "Spindle pole", "Spindle pole centrosome", "Spliceosomal complex", "Spliceosomal snrnp complex", "Spliceosomal tri snrnp complex", "Stereocilia coupling link", "Stereocilium bundle", "Stereocilium membrane", "Stereocilium tip", "Striated muscle thin filament", "Sumo ligase complex", "Supramolecular complex", "Supramolecular polymer", "Swi snf complex", "Swr1 complex", "Synapse", "Synaptic membrane", "Synaptic vesicle membrane", "Synaptonemal structure", "T tubule", "Telomerase holoenzyme complex", "Terminal bouton", "Tertiary granule", "Tertiary granule lumen", "Tertiary granule membrane", "Tetraspanin enriched microdomain", "Tho complex", "Tight junction", "Tim22 mitochondrial import inner membrane insertion complex", "Tim23 mitochondrial import inner membrane translocase complex", "Tor complex", "Torc1 complex", "Trans golgi network", "Trans golgi network membrane", "Trans golgi network transport vesicle", "Trans golgi network transport vesicle membrane", "Transcription elongation factor complex", "Transcription export complex", "Transcription export complex 2", "Transcription factor tfiid complex", "Transcription factor tfiih holo complex", "Transcription factor tfiiic complex", "Transcription preinitiation complex", "Transcription regulator complex", "Transcription repressor complex", "Transferase complex", "Transferase complex transferring phosphorus containing groups", "Translation preinitiation complex", "Translocon complex", "Transport vesicle", "Transport vesicle membrane", "Transporter complex", "Trapp complex", "Tricarboxylic acid cycle enzyme complex", "Triglyceride rich plasma lipoprotein particle", "Trna methyltransferase complex", "Trna splicing ligase complex", "Tubular endosome", "U1 snrnp", "U12 type spliceosomal complex", "U2 snrnp", "U2 type catalytic step 2 spliceosome", "U2 type spliceosomal complex", "U2af complex", "U4 snrnp", "U5 snrnp", "U6 snrnp", "U7 snrnp", "Ubiquitin conjugating enzyme complex", "Ubiquitin ligase complex", "Unconventional myosin complex", "Uniplex complex", "Vacuolar lumen", "Vacuolar membrane", "Vacuolar proton transporting v type atpase v0 domain", "Vacuole", "Varicosity", "Vcp npl4 ufd1 aaa atpase complex", "Vesicle coat", "Vesicle lumen", "Vesicle membrane", "Vesicle tethering complex", "Voltage gated calcium channel complex", "Wash complex", "Weibel palade body", "Wnt signalosome", "X chromosome", "Xy body", "Zona pellucida receptor complex", "Zonula adherens", "Zymogen granule", "Zymogen granule membrane"], "available_proteins": ["AAAS", "AAMP", "AAR2", "AARS", "AARS2", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAP2", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADH5", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP17A", "AKAP8", "AKR1A1", "AKR7A2", "AKT1", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALKBH5", "ALYREF", "AMOT", "ANAPC16", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP3B1", "AP3D1", "AP3M1", "APEH", "APEX1", "API5", "APMAP", "APOL2", "APOOL", "APRT", "AQR", "ARCN1", "ARF4", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARID1A", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL6IP4", "ARL6IP5", "ARL8B", "ARMC1", "ARMCX3", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ASAH1", "ASCC2", "ASCC3", "ASNA1", "ASPH", "ASPM", "ASRGL1", "ATAD1", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATL2", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7B", "ATPAF1", "ATPIF1", "ATRX", "ATXN10", "ATXN2L", "AUP1", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG5", "BAG6", "BAIAP2", "BAK1", "BANF1", "BAP18", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BCAP31", "BCAS2", "BCAT2", "BCCIP", "BCL10", "BCL2L13", "BCLAF1", "BCS1L", "BET1", "BIRC6", "BMS1", "BNIP1", "BOP1", "BRD2", "BRI3BP", "BRIX1", "BSG", "BTF3", "BUB3", "BUD31", "BYSL", "C12orf43", "C12orf73", "C19orf70", "C1QBP", "C1orf35", "C21orf59", "C2CD5", "C2orf49", "CAB39", "CACYBP", "CAD", "CALD1", "CALR", "CALU", "CAND1", "CANX", "CAP1", "CAPN1", "CAPRIN1", "CAPZA1", "CAPZB", "CARHSP1", "CARS2", "CASK", "CASP2", "CASP3", "CAST", "CBFB", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC124", "CCDC47", "CCDC86", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD276", "CD2AP", "CD2BP2", "CD47", "CD81", "CDC23", "CDC27", "CDC37", "CDC42", "CDC45", "CDC5L", "CDC73", "CDCA8", "CDK1", "CDK13", "CDK2", "CDK4", "CDK5RAP3", "CDK6", "CDKAL1", "CDKN2A", "CDKN2AIP", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPV", "CEP170", "CEP44", "CEP55", "CERS2", "CFAP20", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD4", "CHEK2", "CHERP", "CHID1", "CHMP2A", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHUK", "CIAPIN1", "CIRBP", "CISD2", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP2", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLP1", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLSPN", "CLTA", "CLTC", "CMPK1", "CNN2", "CNN3", "CNOT1", "CNOT11", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG7", "COIL", "COL4A3BP", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "CORO1C", "COTL1", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7C", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT2", "CRK", "CRKL", "CRNKL1", "CRTAP", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC22", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5R3", "CYC1", "CYFIP1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DCAF13", "DCAF7", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DICER1", "DIDO1", "DIEXF", "DIP2B", "DIS3", "DIS3L2", "DKC1", "DLAT", "DLD", "DLST", "DNAAF5", "DNAJA1", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC3", "DNAJC8", "DNAJC9", "DNM1", "DNM1L", "DNM2", "DNMT1", "DNTTIP2", "DPF2", "DPM1", "DPP9", "DPYSL2", "DPYSL3", "DRG1", "DSG2", "DSP", "DST", "DSTN", "DTL", "DTYMK", "DUSP3", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "EARS2", "EBNA1BP2", "EBP", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EHD1", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5A", "EIF6", "ELAC2", "ELAVL1", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENO1", "ENY2", "EPB41", "EPB41L2", "EPB41L3", "EPHX1", "EPHX2", "EPPK1", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERC1", "ERCC2", "ERCC6L", "ERGIC3", "ERH", "ERI1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESS2", "ESYT1", "ESYT2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EYA3", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAHD1", "FAM162A", "FAM208A", "FAM3C", "FAM49B", "FAM8A1", "FAM91A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FBL", "FBXO22", "FDFT1", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP1A", "FKBP2", "FKBP4", "FKBP7", "FKBP8", "FKBP9", "FLCN", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNBP4", "FNDC3A", "FNTA", "FNTB", "FOXC1", "FOXRED1", "FRG1", "FSCN1", "FTO", "FTSJ3", "FUCA2", "FUNDC2", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALNT1", "GALNT2", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATAD2A", "GATAD2B", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLM", "GCN1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GGCX", "GGH", "GHITM", "GIGYF2", "GINS1", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG12", "GNG5", "GNL2", "GNL3", "GNL3L", "GNS", "GOLGA3", "GOLGB1", "GOLIM4", "GOPC", "GOT2", "GPAA1", "GPATCH4", "GPD2", "GPI", "GPKOW", "GPR107", "GPR108", "GPS1", "GPT2", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSR", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2E1", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP4", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS4", "HAUS5", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HELLS", "HELZ", "HERC2", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HP1BP3", "HPS6", "HS1BP3", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IGF1R", "IGF2BP1", "IGF2BP3", "IGF2R", "IK", "IKBIP", "ILF2", "ILF3", "ILVBL", "IMMT", "IMP3", "IMPAD1", "IMPDH2", "INA", "INCENP", "INF2", "INTS3", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "ISCU", "ISOC1", "IST1", "ISY1", "ITCH", "ITGB1", "ITPK1", "IVD", "JUP", "KARS", "KAT7", "KCTD12", "KCTD5", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM3B", "KDSR", "KHDRBS1", "KIAA0368", "KIF11", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KLC1", "KLC2", "KLC4", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LAMP1", "LAMTOR1", "LAMTOR2", "LANCL1", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDAH", "LDHA", "LDHB", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC59", "LRWD1", "LSG1", "LSM14A", "LSM2", "LSM6", "LSS", "LTA4H", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LZTS2", "M6PR", "MACF1", "MAGED2", "MAK16", "MANF", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCKS", "MARK2", "MARS", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MCAT", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED17", "MED24", "MED25", "MEPCE", "MESD", "METTL1", "METTL13", "MFF", "MFN2", "MFSD10", "MGST2", "MGST3", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MIPEP", "MKI67", "MLEC", "MMAB", "MMGT1", "MMS19", "MOGS", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPG", "MPHOSPH10", "MPHOSPH6", "MPP2", "MPP6", "MPRIP", "MPST", "MPV17L2", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL44", "MRPL45", "MRPL46", "MRPL50", "MRPL58", "MRPL9", "MRPS10", "MRPS15", "MRPS17", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTX1", "MTX2", "MTX3", "MUT", "MVD", "MVK", "MXRA7", "MYBBP1A", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA25", "NAA35", "NAA40", "NAA50", "NADK2", "NAGLU", "NAMPT", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCAPH2", "NCBP1", "NCDN", "NCK1", "NCKAP1", "NCL", "NCLN", "NCOA5", "NCSTN", "NDC1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4", "NEFL", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NENF", "NES", "NFS1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPA2", "NIPSNAP2", "NKRF", "NLE1", "NLN", "NLRX1", "NME1", "NME2", "NMT1", "NNT", "NOC2L", "NOC3L", "NOC4L", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOSIP", "NPC1", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NSA2", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSMCE2", "NSUN2", "NSUN5", "NT5C3A", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDT1", "NUDT12", "NUDT21", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUTF2", "NVL", "NXF1", "OAT", "OCIAD1", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC3", "OSBP", "OSBPL8", "OSBPL9", "OSGEP", "OTULIN", "OXA1L", "OXSR1", "P3H1", "P4HA1", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAIP1", "PAK1IP1", "PAK2", "PALLD", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCLAF", "PCM1", "PCNA", "PCNP", "PCYOX1", "PDCD11", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDS5A", "PDS5B", "PDXDC1", "PDXK", "PECR", "PEF1", "PELP1", "PES1", "PEX14", "PEX19", "PEX5", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGK1", "PGM1", "PGM2", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF2", "PHF5A", "PHF6", "PHIP", "PI4K2A", "PICALM", "PIGK", "PIGS", "PIGU", "PIH1D1", "PIK3C2A", "PIN1", "PIN4", "PINX1", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN2", "PLA2G15", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMVK", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLRMT", "PON2", "POP1", "POR", "PPA2", "PPAN", "PPHLN1", "PPIB", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPM1F", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R1", "PPP5C", "PPT1", "PPT2", "PQBP1", "PRAF2", "PRC1", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF39", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PSAP", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSPC1", "PTBP1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTK7", "PTPA", "PTPN1", "PTRH2", "PUM1", "PUM3", "PURA", "PUS1", "PWP1", "PWP2", "PXN", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB21", "RAB24", "RAB34", "RAB35", "RAB39A", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB8B", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD51AP1", "RAE1", "RAI14", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP1GDS1", "RAPGEF2", "RARS", "RASA1", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM25", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM8A", "RBMX", "RBMXL1", "RBP1", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "REEP5", "RER1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFLNB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RINT1", "RMDN1", "RMDN3", "RNASEH2A", "RNASEH2B", "RNASET2", "RNF14", "RNF40", "RNMT", "RNPS1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP3", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSU1", "RTCB", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMHD1", "SAMM50", "SAP18", "SAP30BP", "SAR1A", "SARNP", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCRIB", "SCRN1", "SDCBP", "SDE2", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC63", "SEH1L", "SEL1L", "SENP3", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD7", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFXN1", "SFXN4", "SGPL1", "SGTA", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIN3A", "SIRT1", "SIRT2", "SKIV2L2", "SKP1", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC30A5", "SLC35A4", "SLC35B2", "SLC3A2", "SLC9A3R1", "SLFN11", "SLIRP", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SNAP23", "SNAP29", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SOAT1", "SOD2", "SON", "SORD", "SPAG9", "SPART", "SPATA5L1", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPECC1L", "SPEN", "SPOUT1", "SPPL2A", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SREK1", "SRI", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STIM2", "STIP1", "STK4", "STMN1", "STOML2", "STRAP", "STRBP", "STRN", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX17", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACC3", "TACO1", "TAF15", "TAMM41", "TARDBP", "TARS2", "TBCA", "TBCB", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TDP2", "TDRKH", "TECR", "TELO2", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFG", "TFIP11", "TFRC", "TGOLN2", "THOC1", "THOC3", "THOP1", "THRAP3", "THUMPD3", "TIA1", "TIAL1", "TIMELESS", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TKT", "TLN1", "TM9SF2", "TMA16", "TMCO1", "TMED10", "TMED2", "TMED7", "TMEM109", "TMEM11", "TMEM126A", "TMEM14C", "TMEM192", "TMEM199", "TMEM214", "TMEM230", "TMEM33", "TMEM43", "TMEM65", "TMEM87A", "TMEM97", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX4", "TNPO1", "TOE1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOR1AIP2", "TOX4", "TP53", "TP53BP1", "TPD52", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRIM21", "TRIM25", "TRIM27", "TRIM28", "TRIP12", "TRIP13", "TRMT10C", "TRMT112", "TRMT6", "TROVE2", "TRUB1", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPYL1", "TSR1", "TTC1", "TTC19", "TTC26", "TTC37", "TTI1", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNG", "TXNDC12", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UBA1", "UBA2", "UBAP2L", "UBE2K", "UBE2L3", "UBE2N", "UBE2O", "UBE2S", "UBE2V1", "UBE3C", "UBE4A", "UBLCP1", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UCHL5", "UFD1", "UFL1", "UFSP2", "UGGT1", "UHRF1", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP19", "USP28", "USP33", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VPS13A", "VPS18", "VPS26A", "VPS29", "VPS33A", "VPS35", "VPS4A", "VPS51", "VPS53", "VRK1", "VRK3", "WAPL", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR18", "WDR3", "WDR33", "WDR36", "WDR41", "WDR43", "WDR46", "WDR5", "WDR61", "WDR70", "WDR73", "WDR75", "WDR77", "WDR82", "WFS1", "WIPI2", "WIZ", "WRAP53", "WTAP", "XAB2", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YKT6", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H14", "ZC3H18", "ZC3HC1", "ZCCHC11", "ZCCHC8", "ZDHHC13", "ZFR", "ZFYVE16", "ZMPSTE24", "ZNF326", "ZNF622", "ZNF638", "ZPR1", "ZW10", "ZYX"], "leading_proteins": ["AATF", "ABCB10", "ABCB7", "ABCC1", "ABCC4", "ABCF1", "ABHD10", "ABHD12", "ACTN2", "ACTR10", "ACTR1A", "ADPGK", "AIMP1", "AIMP2", "AK1", "AKT1", "AKT2", "ALDH3A2", "ANKFY1", "ANKLE2", "ANLN", "ANXA1", "AP1B1", "AP2A1", "AP2A2", "ARFIP1", "ARFIP2", "ARHGDIA", "ARL6IP5", "ASPM", "ATAD1", "ATAD3A", "ATP2B1", "ATP5B", "ATP5I", "ATP6", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATPAF1", "ATPIF1", "ATRX", "BAIAP2", "BASP1", "BCL10", "BCS1L", "C12orf73", "C19orf70", "CAB39", "CACYBP", "CALR", "CASP3", "CBFB", "CCDC47", "CCNB1", "CD47", "CDCA8", "CDK13", "CDKN2AIP", "CDS2", "CENPV", "CEP55", "CERS2", "CHMP2A", "CHMP7", "CKAP2", "CLNS1A", "CLTA", "CLTC", "CNOT1", "COA3", "COASY", "COL4A3BP", "COLGALT1", "COPZ1", "COX2", "COX4I1", "COX6C", "COX7C", "CPOX", "CPT2", "CTNNB1", "CUL1", "CUL2", "CUL5", "CXADR", "CYB5B", "CYP51A1", "DARS", "DAXX", "DCTN2", "DCTN4", "DDRGK1", "DEK", "DERL1", "DHCR24", "DHFR", "DHX29", "DHX36", "DIABLO", "DIP2B", "DLAT", "DLD", "DNAJA3", "DNAJB6", "DNAJC3", "DNM2", "DPM1", "DPYSL3", "DSP", "DYNC1H1", "DYNC1LI1", "DYNC1LI2", "EARS2", "ECSIT", "EDC3", "EHD1", "EIF3A", "EIF3F", "EIF3M", "EIF4A1", "EIF4B", "EIF4E", "EIF4G1", "EIF4G3", "EIF4H", "ELOA", "ELOC", "ELP2", "ELP4", "EMC7", "EMD", "EPB41L2", "EPPK1", "EPRS", "ERAP1", "ERCC2", "ERCC6L", "ERGIC3", "ERP44", "EXOC2", "EXOC4", "EXOC6", "FABP5", "FBL", "FDXR", "FKBP1A", "FKBP7", "FKBP9", "FNTB", "FUNDC2", "FXR2", "G3BP1", "GAA", "GABARAPL2", "GCC2", "GCFC2", "GINS3", "GLOD4", "GNAI2", "GNG5", "GOLGB1", "GOLIM4", "GPR108", "GRIPAP1", "H1F0", "H1FX", "H2AFX", "H2AFY2", "H4C1*", "HGS", "HINT2", "HIST1H1C", "HIST1H1E", "HMGA1", "HMOX1", "HMOX2", "HNRNPU", "HSD17B11", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA2", "HSPB1", "HSPH1", "HTATSF1", "IARS", "IMPAD1", "IPO11", "IPO8", "JUP", "KARS", "KCTD5", "KDSR", "KIF1A", "KIF23", "KIF2A", "KIF2C", "KMT2A", "KNTC1", "KPNA1", "LAMTOR1", "LAMTOR2", "LARS", "LETM1", "LGALS3BP", "LIG1", "LIMA1", "LRPAP1", "LSM2", "LYPLA1", "M6PR", "MANF", "MAP2K2", "MAP3K7", "MAPK14", "MARC1", "MARCKS", "MARK2", "MARS", "MCCC2", "MCU", "MECP2", "MED24", "MED25", "MFN2", "MFSD10", "MIA3", "MIPEP", "MLEC", "MMGT1", "MOSPD2", "MPG", "MRPL12", "MRPL14", "MRPL17", "MRPL19", "MRPL28", "MRPL38", "MRPL40", "MRPL44", "MRPL45", "MRPL50", "MRPL58", "MRPL9", "MRPS10", "MRPS17", "MRPS23", "MRPS27", "MRPS28", "MRPS35", "MRPS5", "MSMO1", "MSN", "MTFP1", "MTPN", "MTX1", "MTX3", "MXRA7", "MYH9", "NCAPD3", "NCAPG", "NCSTN", "NDUFA11", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF7", "NDUFB11", "NDUFB3", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV2", "NECAP1", "NECAP2", "NEFL", "NEFM", "NELFB", "NOP53", "NPTN", "NRBP1", "NT5C3A", "NUCB2", "NUF2", "NUP188", "OCRL", "OGT", "ORC3", "OXA1L", "OXSR1", "PABPC1", "PAIP1", "PALLD", "PCK2", "PDCD6IP", "PDHB", "PDS5B", "PDXK", "PFDN5", "PFDN6", "PGRMC2", "PHF6", "PIGK", "PIN4", "PKMYT1", "PLS1", "POLA1", "POLA2", "POLE", "POLR1A", "POLR1B", "POLR1C", "POLR2E", "PON2", "PPP2R1A", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4R1", "PQBP1", "PRC1", "PRCP", "PRIM1", "PRKACA", "PRKAG1", "PRKAR1A", "PSMB2", "PSMB6", "PSMC6", "PSMD10", "PSMD14", "PSMD2", "PSMD4", "PSMG1", "PTPA", "PTRH2", "PUM1", "QARS", "RAB10", "RAB3B", "RAB5A", "RABGAP1", "RACGAP1", "RAN", "RANBP9", "RARS", "RASA1", "RBM15", "RBP1", "RDX", "RECQL4", "RETSAT", "REXO2", "RFLNB", "RHOG", "ROCK2", "RPA3", "RPL10A", "RPL12", "RPL13", "RPL22", "RPL23", "RPL23A", "RPL27", "RPL28", "RPL29", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL38", "RPL7", "RPL7A", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPRD1B", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS18", "RPS19", "RPS2", "RPS3A", "RPS6", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RTN1", "RTN3", "RUFY1", "SAP30BP", "SARNP", "SCAF1", "SCAMP1", "SCARB1", "SCD", "SEC11A", "SEPT6", "SEPT9", "SF3A2", "SF3B4", "SFXN4", "SGPL1", "SHOC2", "SIN3A", "SIRT2", "SKP1", "SLC25A10", "SLC25A21", "SLC25A26", "SLC25A32", "SLC29A1", "SLC30A5", "SLC35B2", "SLC3A2", "SLC9A3R1", "SLTM", "SMARCA1", "SMC2", "SMC4", "SMC5", "SMC6", "SMPD4", "SNAP23", "SNAP29", "SNRPA", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNX1", "SNX27", "SNX5", "SPC25", "SPPL2A", "SPTAN1", "SPTBN2", "SRPRA", "SSB", "SSBP1", "STAM", "STAT3", "STAU1", "STMN1", "STOML2", "STT3B", "STUB1", "SUN1", "SURF4", "SURF6", "SYMPK", "SYNGR2", "SYNJ2BP", "TAB1", "TAMM41", "TDRKH", "TFIP11", "TFRC", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TMEM109", "TMEM65", "TMEM87A", "TMX4", "TOMM22", "TOR1AIP1", "TOX4", "TPP1", "TRAPPC5", "TRIP13", "TRMT6", "TTC26", "TTYH3", "TUBB4A", "TUBB4B", "TUBGCP2", "TUBGCP3", "TWF1", "TWF2", "TXNL1", "UBE2N", "UBE2S", "UBXN1", "UFD1", "UGGT1", "UNC119", "UNG", "UQCR10", "UQCRB", "UQCRFS1", "UQCRQ", "USP33", "UTP15", "VPS13A", "VPS18", "VPS26A", "VRK1", "WAPL", "WFS1", "XPO4", "XPOT", "YKT6", "YME1L1", "YTHDC2", "ZDHHC13", "ZMPSTE24", "ZNF622"]} \ No newline at end of file diff --git a/msigdb_gomf/advanced/idx2term.json b/msigdb_gomf/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..7533dc77b12a55017dbd2f8d803218f739bbb958 --- /dev/null +++ b/msigdb_gomf/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Transporter activity", "1": "Ion transmembrane transporter activity", "2": "Lipid binding", "3": "Kinase activator activity", "4": "Monooxygenase activity", "5": "Kinase regulator activity", "6": "Inorganic molecular entity transmembrane transporter activity", "7": "Phosphatidylinositol binding", "8": "Cation transmembrane transporter activity"} \ No newline at end of file diff --git a/msigdb_gomf/advanced/plot_0.png b/msigdb_gomf/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..1f03e84a58305e6678644b0ddc9ad1e7740670e7 --- /dev/null +++ b/msigdb_gomf/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f6abfab32ad7f9a9db2e88c9017228cb6acfad0fa4869d045aa6c33a7e679b25 +size 224265 diff --git a/msigdb_gomf/advanced/plot_1.png b/msigdb_gomf/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..8103d1fd58a935af1d54d89143be29888b56ee45 --- /dev/null +++ b/msigdb_gomf/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fc23476ecb009050fae4b75bb9b0c815d1e2bb34fee0efe18a8f5330f2a9adab +size 220822 diff --git a/msigdb_gomf/advanced/plot_2.png b/msigdb_gomf/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..b2c618564ae86d3dd483006c7eec47c9e21c4a93 --- /dev/null +++ b/msigdb_gomf/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:450cce0ec3c26730c4a7f9005081d9c298842eac506fec112920801f986cbd13 +size 223940 diff --git a/msigdb_gomf/advanced/plot_3.png b/msigdb_gomf/advanced/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..6cd9b544a5958342a96704cb89452ca71726beae --- /dev/null +++ b/msigdb_gomf/advanced/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b324fe4ebfc50439410382296db7bd335c867ed06c73801c3c4245b6cfc04d98 +size 198020 diff --git a/msigdb_gomf/advanced/plot_4.png b/msigdb_gomf/advanced/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..1988482b9655e274d659eada58652301f380243c --- /dev/null +++ b/msigdb_gomf/advanced/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3f955a324fbb510d6cfc69a07e27075fe31e1bed2a50d17da1a0874166d50808 +size 197005 diff --git a/msigdb_gomf/advanced/plot_5.png b/msigdb_gomf/advanced/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..c0d32bd5d407460b863ace412bdd8e459bf215bd --- /dev/null +++ b/msigdb_gomf/advanced/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:38ba481db8fc7e4ab88daebf3eea903fd6051a5a6dd816f640a5625f3e731838 +size 210921 diff --git a/msigdb_gomf/advanced/plot_6.png b/msigdb_gomf/advanced/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..39b2d526527bc3f42fb7df76ab482af934dcdd55 --- /dev/null +++ b/msigdb_gomf/advanced/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ea187cb6dff512af09657f5763d54cd0fec340d50a582d17726197b2b4f2b375 +size 220374 diff --git a/msigdb_gomf/advanced/plot_7.png b/msigdb_gomf/advanced/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..884384dbab7e34eb4146c332aec19b515ffcf219 --- /dev/null +++ b/msigdb_gomf/advanced/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d194b257d64c6cd46048e1e2fcea64266c442d92830d1db054879c00e557a8bb +size 211146 diff --git a/msigdb_gomf/advanced/plot_8.png b/msigdb_gomf/advanced/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..2cb09ed685d335a841d19e863d9dd1fe0c9d0478 --- /dev/null +++ b/msigdb_gomf/advanced/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ce09bc819521ecdb51e555e88f6d78dc49795dabb25d0f5db390eeb53045efb0 +size 215530 diff --git a/msigdb_gomf/basic/idx2term.json b/msigdb_gomf/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..42f5b0e70b94ba8162f642062b6dc877a2acfb7d --- /dev/null +++ b/msigdb_gomf/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Transporter activity", "1": "Ion transmembrane transporter activity", "2": "Lipid binding", "3": "Kinase activator activity", "4": "Monooxygenase activity", "5": "Kinase regulator activity", "6": "Inorganic molecular entity transmembrane transporter activity", "7": "Phosphatidylinositol binding", "8": "Cation transmembrane transporter activity", "9": "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen", "10": "Pdz domain binding", "11": "Scaffold protein binding", "12": "Organic anion transmembrane transporter activity", "13": "Tetrapyrrole binding", "14": "Primary active transmembrane transporter activity", "15": "Endopeptidase activity", "16": "Phospholipid binding", "17": "Phosphatidylinositol phosphate binding", "18": "Active transmembrane transporter activity", "19": "Oxidoreduction driven active transmembrane transporter activity", "20": "Structural constituent of ribosome", "21": "Atpase binding", "22": "Anion transmembrane transporter activity", "23": "Organic acid transmembrane transporter activity", "24": "Nadh dehydrogenase activity", "25": "Gtpase binding", "26": "Protein serine kinase activity", "27": "Protein serine threonine tyrosine kinase activity", "28": "Mrna 5 utr binding", "29": "Protein serine threonine kinase activity", "30": "Chromatin dna binding", "31": "Transferase activity transferring phosphorus containing groups", "32": "Protein kinase activity", "33": "Protein n terminus binding", "34": "Calmodulin binding", "35": "Transition metal ion binding", "36": "Enzyme activator activity", "37": "Kinase binding", "38": "Nuclear receptor coactivator activity", "39": "Protein macromolecule adaptor activity", "40": "Transferase activity transferring one carbon groups", "41": "Protein phosphatase binding", "42": "Molecular adaptor activity", "43": "Kinase activity", "44": "Modification dependent protein binding", "45": "4 iron 4 sulfur cluster binding", "46": "Protein homodimerization activity", "47": "General transcription initiation factor binding", "48": "Structural molecule activity", "49": "Rna polymerase ii specific dna binding transcription factor binding"} \ No newline at end of file diff --git a/msigdb_gomf/basic/plot_0.png b/msigdb_gomf/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..b4561985be7534887393982510958a1cadf78700 --- /dev/null +++ b/msigdb_gomf/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:95598067998273967e683b512496529e0b4592b1ad92a843d54705ad1746df4e +size 135205 diff --git a/msigdb_gomf/basic/plot_1.png b/msigdb_gomf/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..c8ba8c360f016de6dd2cca5af85d59aabd42bca3 --- /dev/null +++ b/msigdb_gomf/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:aacff1f8d8e44b951b9aff8839d18c9a9670866a3bf2364a7b7efb50c1acc89c +size 144096 diff --git a/msigdb_gomf/basic/plot_10.png b/msigdb_gomf/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..085c947f979beb98462570d7a9fd4083a2bbf23b --- /dev/null +++ b/msigdb_gomf/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:36848f2a55b1e1ffb58456de579fcdf0252c2d572a91206935814e18b559f4d5 +size 123260 diff --git a/msigdb_gomf/basic/plot_11.png b/msigdb_gomf/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..9f03e7ebcef5772588451ad54509803cc9a3847a --- /dev/null +++ b/msigdb_gomf/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ed5cae36a623cccb6dbedecabf0d1874d5407682a605c4dfab5c8e240691988a +size 134832 diff --git a/msigdb_gomf/basic/plot_12.png b/msigdb_gomf/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..148b178437dfca34e03e7d4b6c61aa58167062a4 --- /dev/null +++ b/msigdb_gomf/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c5a78e981719a52a4f3ec804e75a62cded4e0f16a0334253918d44c62384b219 +size 139383 diff --git a/msigdb_gomf/basic/plot_13.png b/msigdb_gomf/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..0821b86e66cd64823dd64e1867cc5fcccf433b9a --- /dev/null +++ b/msigdb_gomf/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1fc84934aeb4733aaa1d8fc5a6d4646e7e879fdf229f719fe211b2c8064aef66 +size 132043 diff --git a/msigdb_gomf/basic/plot_14.png b/msigdb_gomf/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..e47fca788615e8fca520b94767262f089a1689c3 --- /dev/null +++ b/msigdb_gomf/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:702221bf3bad89f2427238dd7b6292f603d2ca50272a9ff112fab2284149ce88 +size 146129 diff --git a/msigdb_gomf/basic/plot_15.png b/msigdb_gomf/basic/plot_15.png new file mode 100644 index 0000000000000000000000000000000000000000..a0372824ceb11222cde4b49719092494965320c7 --- /dev/null +++ b/msigdb_gomf/basic/plot_15.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e3c8949bfe4acc476c14b986a7ed7e16c276449cb5f9b2e20a7de74c90daf82e +size 140770 diff --git a/msigdb_gomf/basic/plot_16.png b/msigdb_gomf/basic/plot_16.png new file mode 100644 index 0000000000000000000000000000000000000000..bbb6afea9e49f164e58fda916a46f5b89cab6606 --- /dev/null +++ b/msigdb_gomf/basic/plot_16.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2e36865f49ac1e5c0987e6b2099b0f7a6a76e84f8e27fd8c47649a4d153cfe53 +size 140808 diff --git a/msigdb_gomf/basic/plot_17.png b/msigdb_gomf/basic/plot_17.png new file mode 100644 index 0000000000000000000000000000000000000000..4e47bb65d336a2c472e238d2e66936833c963e41 --- /dev/null +++ b/msigdb_gomf/basic/plot_17.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c02017c0130c51d90bf0f8df99a7314927c2023e1caf45067b5591748e632bd5 +size 139928 diff --git a/msigdb_gomf/basic/plot_18.png b/msigdb_gomf/basic/plot_18.png new file mode 100644 index 0000000000000000000000000000000000000000..d97a9a61faf708293c867d0d3dcc7b83c902ba60 --- /dev/null +++ b/msigdb_gomf/basic/plot_18.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:098b0b34dc24c14c4890b6ce6c9d2e97bad1a9b452a8ef26bd0fc7ebcd2f194a +size 146210 diff --git a/msigdb_gomf/basic/plot_19.png b/msigdb_gomf/basic/plot_19.png new file mode 100644 index 0000000000000000000000000000000000000000..d36f5569c8ae86089152b6ae08ec11ea1870da0c --- /dev/null +++ b/msigdb_gomf/basic/plot_19.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9a61ff38e7b5acd5b0e5f92b47d375f047872faf7ce540dd43b5f1e094d15518 +size 144179 diff --git a/msigdb_gomf/basic/plot_2.png b/msigdb_gomf/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..25d0cf604c278835335558303dda593d8db2db7f --- /dev/null +++ b/msigdb_gomf/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ce37979ef4a2754caaa508e06cd42b691bdefc9f485d26b0b001ac6a42964196 +size 137208 diff --git a/msigdb_gomf/basic/plot_20.png b/msigdb_gomf/basic/plot_20.png new file mode 100644 index 0000000000000000000000000000000000000000..3d1a753c0c4b7457878f73b8f1c9056cbbc4fa25 --- /dev/null +++ b/msigdb_gomf/basic/plot_20.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6272e440e4fe971daa9783c0d3e8147b964b8628151aa51864c29f33ac0dff86 +size 146733 diff --git a/msigdb_gomf/basic/plot_21.png b/msigdb_gomf/basic/plot_21.png new file mode 100644 index 0000000000000000000000000000000000000000..203684385dda84472c84789db7ef0efd7f743a89 --- /dev/null +++ b/msigdb_gomf/basic/plot_21.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e007819d16849127cdcad57072da2fb4f6febf6fea25f7a7c3fd05dc18270bbd +size 138087 diff --git a/msigdb_gomf/basic/plot_22.png b/msigdb_gomf/basic/plot_22.png new file mode 100644 index 0000000000000000000000000000000000000000..8a5c79c0c66e38d3c932162ce99e20c3ae03542c --- /dev/null +++ b/msigdb_gomf/basic/plot_22.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a2f58d03f3677842de49ee74cc7eecf54fc2701dd1cb409ce10c4e8b65ee608a +size 138452 diff --git a/msigdb_gomf/basic/plot_23.png b/msigdb_gomf/basic/plot_23.png new file mode 100644 index 0000000000000000000000000000000000000000..afe2cfbed88392f0f54a2ec3ea10d4cd28e099ad --- /dev/null +++ b/msigdb_gomf/basic/plot_23.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c9241fda0134da1bfe752390e8a149b9581cd9c08ae5fe317974ef07a832f303 +size 141099 diff --git a/msigdb_gomf/basic/plot_24.png b/msigdb_gomf/basic/plot_24.png new file mode 100644 index 0000000000000000000000000000000000000000..b1a00fb4788d9c61eaa08d09fd9efb7e99e6dd2f --- /dev/null +++ b/msigdb_gomf/basic/plot_24.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:34cdd7c6cce609ebf9489c501501d8670402cf3a0080f9544180cf7e6abdbcfc +size 147548 diff --git a/msigdb_gomf/basic/plot_25.png b/msigdb_gomf/basic/plot_25.png new file mode 100644 index 0000000000000000000000000000000000000000..d62539fab5551901d8334708663fe01f1d832373 --- /dev/null +++ b/msigdb_gomf/basic/plot_25.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:223ad8ec00fce8b825aeb78b9a494f2c075be90e68459cb5141e9b7a9a128227 +size 142952 diff --git a/msigdb_gomf/basic/plot_26.png b/msigdb_gomf/basic/plot_26.png new file mode 100644 index 0000000000000000000000000000000000000000..93f10d2da9f311308fe7d7f261f5c6c4927a6f7b --- /dev/null +++ b/msigdb_gomf/basic/plot_26.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0fef43fb4b8ae9743b717603c5624696f5d1cd12a24b7c6e660b648c3a92cdb5 +size 140405 diff --git a/msigdb_gomf/basic/plot_27.png b/msigdb_gomf/basic/plot_27.png new file mode 100644 index 0000000000000000000000000000000000000000..5231cf05af837a868105ce18f62409956c1486df --- /dev/null +++ b/msigdb_gomf/basic/plot_27.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:63e04e549a2b351b3884f1c11c77c90a7e6b0ec5ba57b6e15ad719b0c3d09d32 +size 142714 diff --git a/msigdb_gomf/basic/plot_28.png b/msigdb_gomf/basic/plot_28.png new file mode 100644 index 0000000000000000000000000000000000000000..7ed17dcb2c544d93b67419e7958362d2435e5aab --- /dev/null +++ b/msigdb_gomf/basic/plot_28.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:27b299832dc312985cc369a8962ecb556ee235d9a2c844340bf215a99bece0b5 +size 141578 diff --git a/msigdb_gomf/basic/plot_29.png b/msigdb_gomf/basic/plot_29.png new file mode 100644 index 0000000000000000000000000000000000000000..8949767da6769e7de3d7bb0d83373191258275e2 --- /dev/null +++ b/msigdb_gomf/basic/plot_29.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:78130665a83b802e933ff42b13e3c9ed0163e190bdace8a9c7ffd06df97efb53 +size 142150 diff --git a/msigdb_gomf/basic/plot_3.png b/msigdb_gomf/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..0ef7588a70c1ba87c94e7dd548baaf9c885de304 --- /dev/null +++ b/msigdb_gomf/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:339f46f317beedf490eb5e3206b0b0a810a390671f15948de6e053d5439b5564 +size 137026 diff --git a/msigdb_gomf/basic/plot_30.png b/msigdb_gomf/basic/plot_30.png new file mode 100644 index 0000000000000000000000000000000000000000..f02522d095f687603645bee19584baf50ccb9104 --- /dev/null +++ b/msigdb_gomf/basic/plot_30.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3a303395d908dcd5dbae837ecbe3e06aad16f52fae8cde9ca35fcb3403e1af0d +size 146269 diff --git a/msigdb_gomf/basic/plot_31.png b/msigdb_gomf/basic/plot_31.png new file mode 100644 index 0000000000000000000000000000000000000000..b635060282633ab7afd8c9865fd2bdd462ceb047 --- /dev/null +++ b/msigdb_gomf/basic/plot_31.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:264ecc9d29079bfeef39ef91593dbb03f52eb588c18194487333d71d421bb72b +size 150271 diff --git a/msigdb_gomf/basic/plot_32.png b/msigdb_gomf/basic/plot_32.png new file mode 100644 index 0000000000000000000000000000000000000000..9523e90c3b705b166a5647270221236c57bdc311 --- /dev/null +++ b/msigdb_gomf/basic/plot_32.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3dbc8761251e37d79b05796d475eb1a4efd3e04e5da5faa9064eb31b5a27fd1d +size 138263 diff --git a/msigdb_gomf/basic/plot_33.png b/msigdb_gomf/basic/plot_33.png new file mode 100644 index 0000000000000000000000000000000000000000..94738139930f554edb2233a0283fbd3c4b325024 --- /dev/null +++ b/msigdb_gomf/basic/plot_33.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4262bea8d5cd32cf094dc0c6805516e503d5113cf3190c3b80235d0d53a6d886 +size 147118 diff --git a/msigdb_gomf/basic/plot_34.png b/msigdb_gomf/basic/plot_34.png new file mode 100644 index 0000000000000000000000000000000000000000..d17454b5913314d167b5ca1397fa0b27a596ee9b --- /dev/null +++ b/msigdb_gomf/basic/plot_34.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:690e499103bc497bc75a89b6eb9883412660ed4d2a700f2e22ab9eac0119c0ed +size 140862 diff --git a/msigdb_gomf/basic/plot_35.png b/msigdb_gomf/basic/plot_35.png new file mode 100644 index 0000000000000000000000000000000000000000..680bf73aaf097b34abc3b930c898a28f7e907569 --- /dev/null +++ b/msigdb_gomf/basic/plot_35.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4002e8c920295928fd99354211abaedf8b50ccd70191f81c0bae7aafc1eafe3a +size 143351 diff --git a/msigdb_gomf/basic/plot_36.png b/msigdb_gomf/basic/plot_36.png new file mode 100644 index 0000000000000000000000000000000000000000..8385a1c899a9df0e7ac3c2fea98d58dd4e8b3e21 --- /dev/null +++ b/msigdb_gomf/basic/plot_36.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c79e1811071a205b93914367a2246cdd811c77ba7acb0d169e7e60fba58f44ba +size 145307 diff --git a/msigdb_gomf/basic/plot_37.png b/msigdb_gomf/basic/plot_37.png new file mode 100644 index 0000000000000000000000000000000000000000..11b8fbfe63db5c4111009e7fe32b10acd0599706 --- /dev/null +++ b/msigdb_gomf/basic/plot_37.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:60348574565a57d6e2f1eb041a474e6d65255bd40c7887101094643318c71208 +size 138909 diff --git a/msigdb_gomf/basic/plot_38.png b/msigdb_gomf/basic/plot_38.png new file mode 100644 index 0000000000000000000000000000000000000000..62db0f2adee0250c291e3b85f8bf57abe3faabc1 --- /dev/null +++ b/msigdb_gomf/basic/plot_38.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3275afd6475829d32b72d33de32c0ece2ff5518cb292d188a9f7d98f034a1e04 +size 155133 diff --git a/msigdb_gomf/basic/plot_39.png b/msigdb_gomf/basic/plot_39.png new file mode 100644 index 0000000000000000000000000000000000000000..8a81d9c8fbf671f054139fdb4cf38439954cb92b --- /dev/null +++ b/msigdb_gomf/basic/plot_39.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:cb10b4530d5eb62b1bbb021564d5ad57069d917653a381a7ea13dd3e18584733 +size 153209 diff --git a/msigdb_gomf/basic/plot_4.png b/msigdb_gomf/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..d828ecdc11c83a42319f354e3e8baa1b33226daf --- /dev/null +++ b/msigdb_gomf/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e2c5861b18a94f53efd1eaaac1c44f37b432a18f09c31f78bde367fdc7cb6cba +size 137585 diff --git a/msigdb_gomf/basic/plot_40.png b/msigdb_gomf/basic/plot_40.png new file mode 100644 index 0000000000000000000000000000000000000000..3337709caa26c62feb92c73ade7e0ef067d9d2de --- /dev/null +++ b/msigdb_gomf/basic/plot_40.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:909bc7aae60da10352f473b7bf14277aebc43ec8f469b8ecd55ab62509cb5736 +size 153550 diff --git a/msigdb_gomf/basic/plot_41.png b/msigdb_gomf/basic/plot_41.png new file mode 100644 index 0000000000000000000000000000000000000000..227d4ebc9852f1db9f541cc2c5abf5f94067f019 --- /dev/null +++ b/msigdb_gomf/basic/plot_41.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1ed6757d284251f4d3ef8ee2c63b6c3ec33ccfc6a05e9e247c4ac060fd76eae4 +size 150804 diff --git a/msigdb_gomf/basic/plot_42.png b/msigdb_gomf/basic/plot_42.png new file mode 100644 index 0000000000000000000000000000000000000000..5362beb9de49a6489178a168073315fd4cacdf80 --- /dev/null +++ b/msigdb_gomf/basic/plot_42.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5f25d434d69cf7af679b3d699d87b5db7481ec37ec41dac87229ffeb07e1a7a9 +size 148460 diff --git a/msigdb_gomf/basic/plot_43.png b/msigdb_gomf/basic/plot_43.png new file mode 100644 index 0000000000000000000000000000000000000000..63b0c28892c8c75e493e2c52fa0d8036da1c8b69 --- /dev/null +++ b/msigdb_gomf/basic/plot_43.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a26e8da4c83dbb879101c3ea99c65ae2666f7493102053e7aa0f6ffae8aeaeb1 +size 143292 diff --git a/msigdb_gomf/basic/plot_44.png b/msigdb_gomf/basic/plot_44.png new file mode 100644 index 0000000000000000000000000000000000000000..60e24ca879b4170bd68b48c96abef918eb152745 --- /dev/null +++ b/msigdb_gomf/basic/plot_44.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:112ff806187b1c85e12c839ca6f01be370571feba199d4a1122602453802f707 +size 148696 diff --git a/msigdb_gomf/basic/plot_45.png b/msigdb_gomf/basic/plot_45.png new file mode 100644 index 0000000000000000000000000000000000000000..72be7e54eae8105b8caa5ee518a6394714f7900a --- /dev/null +++ b/msigdb_gomf/basic/plot_45.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f249016bf3e7f9cc7de273021a217c5d7ce3c47a489cce93f3950738e37a35fe +size 149281 diff --git a/msigdb_gomf/basic/plot_46.png b/msigdb_gomf/basic/plot_46.png new file mode 100644 index 0000000000000000000000000000000000000000..596160ec7d23c111726f7e6e3f753783f57230bb --- /dev/null +++ b/msigdb_gomf/basic/plot_46.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:80d1ac8c53fcb064757d5a099064e488cedac6af5228da118aba550940ea6540 +size 145761 diff --git a/msigdb_gomf/basic/plot_47.png b/msigdb_gomf/basic/plot_47.png new file mode 100644 index 0000000000000000000000000000000000000000..dcb6cd82e9ccf40db1dd8d009da7d756c0770e11 --- /dev/null +++ b/msigdb_gomf/basic/plot_47.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a20b2b6de1ac1e1df8a8f592061a1d69e81e5d9961c8398170fad9194a23a73f +size 137692 diff --git a/msigdb_gomf/basic/plot_48.png b/msigdb_gomf/basic/plot_48.png new file mode 100644 index 0000000000000000000000000000000000000000..00d5674c7b71ac2e24a07fc94825dfd9648b8640 --- /dev/null +++ b/msigdb_gomf/basic/plot_48.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4eeed2088c39219047aacca187d60b9269bcb165ee16f150f4b284151c52227c +size 147980 diff --git a/msigdb_gomf/basic/plot_49.png b/msigdb_gomf/basic/plot_49.png new file mode 100644 index 0000000000000000000000000000000000000000..4c557f676090798f810011f2c3bc6d13781d8ac4 --- /dev/null +++ b/msigdb_gomf/basic/plot_49.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4c51ee14c83564624569172c68505b684e1a53a574d1c40e969a787a97582fbf +size 155077 diff --git a/msigdb_gomf/basic/plot_5.png b/msigdb_gomf/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..c2b22907a357dab30928869f03dc99403a857963 --- /dev/null +++ b/msigdb_gomf/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6b9edc98f9e88d7eea3a50cddfc92470c29a6c927cee4dc982519732bf32309a +size 136593 diff --git a/msigdb_gomf/basic/plot_6.png b/msigdb_gomf/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..e8bd69c0f284c3f921e759e7e445aab4eb25f084 --- /dev/null +++ b/msigdb_gomf/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:46a50dca6117d90c13e1b1c284cc8cf644a9757a412d6de00382950ad5129c86 +size 140101 diff --git a/msigdb_gomf/basic/plot_7.png b/msigdb_gomf/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..f3c7df145608093a591cd904c81a88adfbdd7116 --- /dev/null +++ b/msigdb_gomf/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9b246f1a8ed59e54fb5817ec524579711810d40c372fbc0d9f9728900663775f +size 144017 diff --git a/msigdb_gomf/basic/plot_8.png b/msigdb_gomf/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..396353bb08a37e2bcd56e6008acee5733bc8d19e --- /dev/null +++ b/msigdb_gomf/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:da86f14185ae925a7267b33e6e3154fa9100a1725b3b62dd1718245888c16ad2 +size 141765 diff --git a/msigdb_gomf/basic/plot_9.png b/msigdb_gomf/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..ec7a3193648fe984032eb12b0d5629f003e98f4a --- /dev/null +++ b/msigdb_gomf/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9310632d9ba72c91565e70626577314fe4a1d2b91c3f06ee811250245d931a6c +size 138345 diff --git a/msigdb_gomf/consensus.joblib b/msigdb_gomf/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..81f1386966cb8860bf54f78a2ceb2cb1964457d1 --- /dev/null +++ b/msigdb_gomf/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e56fa2d26876dfbe974d1e4bcdd765adc8a3c2c24ced5452e1fce961fe010542 +size 183846 diff --git a/msigdb_gomf/df_merge.tsv b/msigdb_gomf/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..3bb6744fe1e3271163131a9ced39f105af60e111 --- /dev/null +++ b/msigdb_gomf/df_merge.tsv @@ -0,0 +1,18 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Transporter activity 31 152 4.7423431791082775 2.1126035263385745e-06 62.22330097087379 172.27912621359224 2.173366592838491 0.2707201784543502 25.984753572620328 19.29276868436311 2.593156143256053 0.3916539604106395 1.0 3.4547551545681746e-06 9.55806378822552e-07 5.06390426429591e-07 6.557008839996935e-05 +Ion transmembrane transporter activity 19 90 2.9779505263805306 0.002901828205903 37.34466019417476 101.497572815534 2.0154097423383375 0.2561362875319209 17.172953606300336 11.579295798802024 2.277787478419462 0.3756175790939143 1.0 0.0031507382562496 0.0005504613598615 0.0010428473466309 0.0070166832919558 +Lipid binding 22 129 2.735727061574658 0.0062242628263091 30.883495145631063 138.65533980582524 0.9844637598707308 0.4289871747751645 8.92748670410201 14.760635317682617 1.446857667744565 0.4068298387995807 1.0 0.0047170389987107 0.0027235252040205 0.0192149006615846 0.0872315537853201 +Macromolecule transmembrane transporter activity 4 12 2.5791546098830485 0.0099042447043626 4.820388349514563 12.281553398058252 1.6605285757306012 0.1306403746261988 2.4754663863133306 1.0160601209961664 1.3599823000893485 0.2280235038874096 1.0 0.0001055314719321 0.0007721292992325 8.046377297977821e-05 0.0020589587060794 +Protein transmembrane transporter activity 4 11 2.5108915776805203 0.012042667793888 4.37621359223301 11.264563106796116 1.6409152716253632 0.1284874270119089 2.3258190399954897 0.995332092405782 1.387057072324357 0.2266762256512647 1.0 6.357667188483331e-05 0.0004698914927371 3.4027055470100374e-05 0.0009252060068251 +Kinase activator activity 5 14 2.46804119220702 0.0135854685135172 5.189320388349515 14.283980582524272 -0.3539998788812653 0.5595906102161438 3.10231396949317 2.7772368190591026 0.7980193695452926 0.2918182504095425 1.0 0.0450273794310473 0.142361939470236 0.0893826433292889 0.0549319620867589 +Protein transporter activity 4 15 2.462841234186012 0.0137840937891782 6.053398058252427 14.696601941747574 1.6882240898296943 0.1359359142649309 2.957968193176 1.443999336657768 1.4805047019217734 0.2345897542974644 1.0 0.0002094223372061 0.0015067102674828 0.0002504501206939 0.000927186831798 +Dna secondary structure binding 3 12 2.304714964043447 0.0211825422655866 3.2184466019417477 10.87135922330097 -0.1978360381474947 0.5285253039842787 2.1790818219962445 1.7010719342013587 0.9128854571916576 0.2949667069435236 1.0 0.0116969452261847 0.0410947893580433 0.0485138308626968 0.0833588252706405 +Monooxygenase activity 6 8 2.269255233580767 0.0232528091559285 4.043689320388349 8.322815533980583 1.6049222537693364 0.1501440468766332 1.612461779657682 1.2307404965531048 1.237349324058907 0.2369071661653372 1.0 0.0070670490819082 0.0254170330798906 3.123245220022367e-05 0.000206673833515 +Kinase regulator activity 9 43 2.2476266292854192 0.0246000080737245 13.218446601941748 44.83495145631068 -0.3373463512750215 0.6108791072313295 6.347604816570012 5.572291169809655 0.7810415500988158 0.3158561347608688 1.0 0.1752615096992375 0.1855683448135747 0.0364255404707469 0.0830528380882472 +Inorganic molecular entity transmembrane transporter activity 11 67 2.206285827891804 0.0273639930477653 28.058252427184467 75.9635922330097 1.5031303400189615 0.2894264293069549 11.721339963426631 9.38477049228959 2.153051736566399 0.3821536813265525 1.0 0.0054817326666829 0.0070667612470763 0.0287174633026667 0.0727451604057441 +Cadherin binding involved in cell cell adhesion 0 10 2.141917286253739 0.032200138579828 2.2766990291262137 10.3252427184466 0.372302405047856 0.5406047143015139 1.9096435840633712 0.5837971529949741 0.8421502510210774 0.300113217733196 1.0 0.0683810764565047 0.1297953400165049 0.3006122829361112 0.5195845375548764 +Sulfur compound transmembrane transporter activity 4 7 2.108969387617892 0.0349472240789023 2.9635922330097086 6.752427184466019 1.4746434057995097 0.1672652154050841 1.7026919602194592 1.5538455059459366 1.0954441166028872 0.2266277553273111 1.0 0.1280604643503683 0.0023307962311057 0.0044765262200217 0.0110817055396115 +Tau protein binding 2 14 2.098881430440717 0.0358273541863436 6.109223300970874 16.856796116504853 -0.2107866501387664 0.5688162745436043 3.9357969275600393 2.5325794493301457 0.8302528024929796 0.2889230627221487 1.0 0.1723099894081314 0.3100914289348834 0.0673084533265038 0.1213829168478661 +Oxidized dna binding 0 6 2.064171021756824 0.0390015040121833 2.6359223300970873 5.798543689320389 -0.0395651938079618 0.5634945882730246 1.670262718067264 0.9657723985293564 0.8496532397346247 0.293568676332217 1.0 0.0461123069087121 0.088498207465679 0.2120396274437268 0.3865233555305862 +Phosphatidylinositol binding 16 50 1.987098650169666 0.0469114658097706 12.95388349514563 54.820388349514566 -0.0074000562460658 0.7210357901311893 6.1431396313380295 7.648007027956374 0.6670548934523987 0.2940747522681988 1.0 0.2389579237234044 0.1100307449508172 0.1860832626893073 0.0907331241408876 +Cation transmembrane transporter activity 9 61 1.9738298420950535 0.0484010943580244 25.62135922330097 70.51699029126213 1.766742880952279 0.2698419237572138 12.29126021871486 8.422243011776631 2.00238274385689 0.3706372466673562 1.0 0.0229384919777869 0.0197484060770074 0.0954612682176383 0.2129404199005011 diff --git a/msigdb_gomf/metrics.json b/msigdb_gomf/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..f1c2a8e3bb61143bd5f5fb27a7877812aa81f531 --- /dev/null +++ b/msigdb_gomf/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2772, + "annotations_size": 1329, + "title": "Average number of proteins per term", + "value": 15.358916478555305 +} \ No newline at end of file diff --git a/msigdb_gomf/paths.json b/msigdb_gomf/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..e1e505a6726ca33c895c3f8db9a7d82059bb8ecc --- /dev/null +++ b/msigdb_gomf/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gomf/fragment/C321/C321_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gomf/result.tsv b/msigdb_gomf/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..d14e3c3306d76013af93440438c3e35ba1876beb --- /dev/null +++ b/msigdb_gomf/result.tsv @@ -0,0 +1,363 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Transporter activity 0.5368975862086651 4.7423431791082775 2.1126035263385745e-06 0.0028037152805653 0.0028076500865052 152 O60830,Q99595,Q8IUH4,Q9NZD2,Q9Y5P4,P33527,Q6P4A7,Q8WTV0,P00846,Q14728,Q9NS69,Q8TAD4,O75027,Q8N4V1,Q8NE86,Q9BQT8,Q9Y584,P21281,O14925,Q9UDW1,O75489,Q70HW3,Q01469,P56385,O15439,Q9C0H2,O15173,O43676,Q9BVC6,Q8IXU6,Q8NE01 31 +Ion transmembrane transporter activity 0.4818872528776141 2.9779505263805306 0.002901828205903 0.978976954271612 0.0296656129665008 90 O95202,Q8IUH4,P33527,Q6P4A7,P00846,Q14728,Q8TAD4,Q8N4V1,Q9H2D1,Q8NE86,Q9BQT8,P21281,Q9UDW1,Q70HW3,P56385,O15439,Q8TB61,Q9C0H2,Q9BVC6 19 +Lipid binding 0.4387351198333962 2.735727061574658 0.0062242628263091 0.9997509598209878 0.05589219794706 129 P55145,A6NIH7,Q7KZI7,P09455,Q9Y5P4,Q9NZD2,Q8WTV0,P35609,Q92783,Q8NCC3,Q9BWH2,O14773,Q92643,Q6IBS0,Q13596,Q13432,P31749,Q01469,Q9H0H5,P53365,O94973,O15173 22 +Macromolecule transmembrane transporter activity 0.8223848796132139 2.5791546098830485 0.0099042447043626 0.9999982011416336 0.0803193097601696 12 O60830,Q9Y584,Q9NS69,Q99595 4 +Tripeptide transmembrane transporter activity 0.9682310469314076 2.570566572058424 0.0101532310306309 0.9999987122490622 0.0803193097601696 2 P33527 1 +Glutathione transmembrane transporter activity 0.9682310469314076 2.570566572058424 0.0101532310306309 0.9999987122490622 0.0803193097601696 2 P33527 1 +Abc type glutathione s conjugate transporter activity 0.9682310469314076 2.570566572058424 0.0101532310306309 0.9999987122490622 0.0803193097601696 2 P33527 1 +Atpase coupled lipid transmembrane transporter activity 0.9682310469314076 2.570566572058424 0.0101532310306309 0.9999987122490622 0.0803193097601696 2 P33527 1 +Oligopeptide transmembrane transporter activity 0.9682310469314076 2.570566572058424 0.0101532310306309 0.9999987122490622 0.0803193097601696 2 P33527 1 +Peptide transmembrane transporter activity 0.9682310469314076 2.570566572058424 0.0101532310306309 0.9999987122490622 0.0803193097601696 2 P33527 1 +Heme transmembrane transporter activity 0.9635379061371838 2.5504260957032585 0.0107591332576886 0.9999994292794508 0.0842894313044524 2 O75027 1 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced flavin or flavoprotein as one donor and incorporation of one atom of oxygen 0.9610108303249096 2.5395644357449414 0.0110990598030693 0.9999996385421674 0.0842894313044524 2 P30519 1 +Protein transmembrane transporter activity 0.8378839523592444 2.5108915776805203 0.012042667793888 0.9999998983627696 0.0904220649608884 11 O60830,Q9Y584,Q9NS69,Q99595 4 +Ceramide 1 phosphate binding 0.9483754512635374 2.4850801727322835 0.0129522261011212 0.9999999701164342 0.0932333055563574 2 Q9Y5P4 1 +Ceramide 1 phosphate transfer activity 0.9483754512635374 2.4850801727322835 0.0129522261011212 0.9999999701164342 0.0932333055563574 2 Q9Y5P4 1 +Kinase activator activity 0.7374203055826002 2.4680411922070196 0.0135854685135172 0.9999999872642558 0.095411774196968 14 Q7KZI7,Q9Y376,P36507,Q13043,P14635 5 +Protein transporter activity 0.7289344172391552 2.462841234186012 0.0137840937891782 0.9999999902547788 0.095411774196968 15 O60830,Q9Y584,Q9NS69,Q99595 4 +Retinoid x receptor binding 0.931768953068592 2.413028044453171 0.0158206022147484 0.999999999375253 0.1072733690989831 2 Q71SY5 1 +Potassium channel inhibitor activity 0.930324909747292 2.4067389144038356 0.0160956721599068 0.999999999569111 0.1085845091396759 2 O43768 1 +Filamin binding 0.918772563176895 2.356290056799484 0.0184584982792699 0.9999999999823552 0.1199480653975492 2 Q8N5W9 1 +Dna translocase activity 0.9115523465703969 2.32463755181612 0.02009134906733 0.9999999999980697 0.1265469332250312 2 Q2NKX8 1 +Dna secondary structure binding 0.763911755031959 2.304714964043447 0.0211825422655866 0.9999999999995608 0.1321671299106324 12 O94761,Q03164,P17096 3 +Calmodulin dependent protein phosphatase activity 0.9018050541516236 2.281759132162843 0.0225035648131903 0.9999999999999272 0.1359419892578637 2 P49593 1 +Calcium dependent protein serine threonine phosphatase activity 0.9018050541516236 2.281759132162843 0.0225035648131903 0.9999999999999272 0.1359419892578637 2 P49593 1 +Monooxygenase activity 0.8660977430644858 2.269255233580767 0.0232528091559285 0.9999999999999736 0.1392026277848154 8 P30519,P61457,P09601,Q6UW02,Q15800,Q16850 6 +Kinase regulator activity 0.5138885668708304 2.2476266292854192 0.0246000080737245 0.9999999999999958 0.1453040476887995 43 Q7KZI7,Q9Y376,P04792,Q13217,P36507,P42574,Q9Y3B8,Q13043,P14635 9 +Inorganic molecular entity transmembrane transporter activity 0.462393117506266 2.206285827891804 0.0273639930477653 1.0 0.1534461888627856 67 P21281,Q8TAD4,Q9UDW1,Q9C0H2,Q8IUH4,Q8N4V1,Q8NE86,P33527,P00846,P56385,O15439 11 +Arylesterase activity 0.8714801444043305 2.1472960742400886 0.0317697181709162 1.0 0.173040801021097 2 Q15165 1 +Sulfur compound transmembrane transporter activity 0.8565948557515567 2.108969387617892 0.0349472240789023 1.0 0.185779443203445 7 O15439,Q8TB61,P33527,Q70HW3 4 +Tau protein binding 0.6666056258905497 2.098881430440717 0.0358273541863436 1.0 0.1894130916326918 14 Q7KZI7,Q9UNE7 2 +1 alkyl 2 acetylglycerophosphocholine esterase activity 0.8581227436823092 2.0875718456703427 0.0368364738857214 1.0 0.1904890030899757 2 Q15102 1 +Phosphatidylinositol binding 0.4754953787787621 1.987098650169666 0.0469114658097706 1.0 0.2214274392439421 50 Q92643,Q6IBS0,Q13596,P31749,Q12792,P53365,P53367,Q9Y5P4,Q9H0H5,O15294,Q9P2R3,Q9BPX3,Q8WTV0,P35609,Q92783,Q9BWH2 16 +Cation transmembrane transporter activity 0.4531153174763834 1.9738298420950535 0.0484010943580244 1.0 0.2264966704289241 61 P21281,Q8TAD4,Q9UDW1,Q8IUH4,Q8N4V1,Q70HW3,Q8NE86,P00846,P56385 9 +Rna polymerase ii c terminal domain binding 0.8299638989169662 1.9607235315820073 0.0499112825013416 1.0 0.2303292454766054 2 Q9H7N4 1 +Calcium cation antiporter activity 0.8285198555956664 1.9541854293636591 0.0506792918385472 1.0 0.230973001230673 2 O95202 1 +Cation cation antiporter activity 0.8285198555956664 1.9541854293636591 0.0506792918385472 1.0 0.230973001230673 2 O95202 1 +Cell cell adhesion mediator activity 0.6099770664148311 1.952063404914705 0.0509306773144966 1.0 0.230973001230673 18 Q9Y639,Q9UQB8,P78310,P14923 4 +Cell adhesion mediator activity 0.5891972103425387 1.9394266298442389 0.0524494105151331 1.0 0.2346978672545858 20 Q9UQB8,P14923,P78310,Q9Y639 4 +Lipid transporter activity 0.622287040170051 1.9259680496778568 0.0541083634161103 1.0 0.2405017223411727 16 Q01469,Q9Y5P4,P33527,O15439 4 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen 0.5611939129056068 1.923326712107338 0.0544390319238674 1.0 0.2411649114227328 25 Q9BU89,P30519,P61457,P09601,Q6UW02,Q15800,Q16850 7 +Pdz domain binding 0.6225657912964548 1.893591638700974 0.0582792341987052 1.0 0.2504797690892236 15 Q9UQB8,Q15067,P78310,P36507,P63218,Q96A65 6 +Adenylate cyclase binding 0.8140794223826697 1.8886363936357355 0.0589405669213916 1.0 0.2504797690892236 2 Q02952 1 +Dna dna annealing activity 0.849459452668519 1.8839452105502297 0.0595723869474345 1.0 0.2504797690892236 5 O94761,P46100 2 +Phosphatidylinositol trisphosphate phosphatase activity 0.8115523465703953 1.8771347465045036 0.0604996281998801 1.0 0.2504797690892236 2 Q01968 1 +Inositol polyphosphate 5 phosphatase activity 0.8115523465703953 1.8771347465045036 0.0604996281998801 1.0 0.2504797690892236 2 Q01968 1 +Inositol phosphate phosphatase activity 0.8115523465703953 1.8771347465045036 0.0604996281998801 1.0 0.2504797690892236 2 Q01968 1 +Phosphatidylinositol phosphate 5 phosphatase activity 0.8115523465703953 1.8771347465045036 0.0604996281998801 1.0 0.2504797690892236 2 Q01968 1 +Phosphatidylinositol 4 5 bisphosphate 5 phosphatase activity 0.8115523465703953 1.8771347465045036 0.0604996281998801 1.0 0.2504797690892236 2 Q01968 1 +Phosphatidylinositol 4 5 bisphosphate phosphatase activity 0.8115523465703953 1.8771347465045036 0.0604996281998801 1.0 0.2504797690892236 2 Q01968 1 +Phosphatidylinositol 3 4 5 trisphosphate 5 phosphatase activity 0.8115523465703953 1.8771347465045036 0.0604996281998801 1.0 0.2504797690892236 2 Q01968 1 +Inositol trisphosphate phosphatase activity 0.8115523465703953 1.8771347465045036 0.0604996281998801 1.0 0.2504797690892236 2 Q01968 1 +Potassium channel regulator activity 0.8227538983798679 1.8612329237105267 0.0627112908465628 1.0 0.2572324244909936 6 O43768,P31749 2 +Scaffold protein binding 0.576036363468285 1.8590529592937353 0.0630196320848344 1.0 0.2577018185869075 20 Q9UQB8,O43318,P36507,Q9Y4P1,P15924 5 +Organic anion transmembrane transporter activity 0.5388341661453028 1.837564774455403 0.0661265634518795 1.0 0.2639105190016452 27 Q8TB61,Q9BQT8,Q9H2D1,Q99808,O14745,P33527,O15439,Q14728,Q9UBX3 9 +Protein serine threonine kinase activator activity 0.7582290830103858 1.8154563642271349 0.0694538059510241 1.0 0.2747146074669972 8 Q9Y376,Q13043,P14635 3 +Molecular transducer activity 0.538357286616348 1.8011103782297018 0.0716854842845629 1.0 0.2793841894844108 26 Q9NWH9,Q9BUN8,Q8WTV0,P20645 4 +Cyclin dependent protein serine threonine kinase inhibitor activity 0.7906137184115505 1.781507407659833 0.0748295958269109 1.0 0.2865951955445667 2 P42574 1 +Tetrapyrrole binding 0.6004037962782472 1.7709166710133792 0.076574559664027 1.0 0.2909909421085061 15 O43169,O15173,P30519,Q6UW02,Q16850 5 +Primary active transmembrane transporter activity 0.4543543610893873 1.7687823958634066 0.0769301956606529 1.0 0.2909909421085061 48 Q9UDW1,O75027,O75489,O43676,P33527,O15439 6 +Abc type transporter activity 0.7720451679353058 1.7623005123579811 0.0780185373731336 1.0 0.2926592850060887 7 P33527,O75027 2 +Fatty acid binding 0.7218545249545064 1.7554911106192084 0.0791753398579844 1.0 0.2955731086271384 9 Q01469,O15254,P09455 3 +Lim domain binding 0.7772563176895283 1.7202213024378212 0.0853922222179801 1.0 0.3092268755523041 2 P35609 1 +Endopeptidase activity 0.4296828200227191 1.7153315410830632 0.0862844589140918 1.0 0.3099244483698056 60 Q92643,O75844,Q8TEY7,Q99797,P49721,P28072,P67812,Q9NZ08,Q8TCT8,Q96TA2,Q13867,P42574,Q13043,Q9Y4P1,O14773 15 +Misfolded protein binding 0.640345838640218 1.6973767459242362 0.089625456069454 1.0 0.3167878487135755 12 Q9BUN8,Q13217,Q9UNE7 3 +Cargo receptor activity 0.7718212691298469 1.6563870054656378 0.0976434709329741 1.0 0.3324904132941906 6 Q5JRA6,P02786,O15260,Q8WTV0 4 +Cyclin dependent protein serine threonine kinase regulator activity 0.7910905882122068 1.6555700546600178 0.0978089186324129 1.0 0.3324904132941906 5 P14635 1 +Passive transmembrane transporter activity 0.4966810201937261 1.637197746108918 0.1015891578471741 1.0 0.3426700273576001 30 Q9C0H2,Q8NE86,Q9BVC6,P00846 4 +Phospholipid binding 0.3841500060252947 1.632657057006005 0.1025411438623069 1.0 0.3429519708122717 81 Q92643,Q6IBS0,P31749,Q9NZD2,Q9Y5P4,Q9H0H5,Q8WTV0,P53365,Q92783,Q8NCC3,P35609,Q9BWH2,O14773 13 +Cation channel activity 0.5497516916046684 1.5972484047752011 0.1102103467780943 1.0 0.3598760463589371 18 P00846,Q8NE86 2 +Ceramide binding 0.7477619211619377 1.5585444630536611 0.1191042364900418 1.0 0.3759846325303222 6 Q9Y5P4 1 +Protein carrier chaperone 0.6550075531153388 1.549763257592012 0.1211983488699908 1.0 0.3782968689340742 10 Q15070,Q8N4V1 2 +Phosphatidylinositol phosphate binding 0.4786773338881792 1.539756425102767 0.1236197371770373 1.0 0.3797074606562942 31 Q6IBS0,P31749,Q12792,P53367,Q9Y5P4,Q9H0H5,O15294,Q9P2R3,Q9BPX3,P35609,P53365,Q9BWH2 12 +Annealing activity 0.6525133962677623 1.538006420064784 0.1240470450431312 1.0 0.3797074606562942 10 O94761,P46100 2 +Active transmembrane transporter activity 0.4033610577678491 1.5303765836051837 0.1259235417037838 1.0 0.3829574071494936 64 O95202,P13073,P21281,O75306,P51970,O75027,Q9UDW1,O75489,O43676,Q8NE86,P33527,O15439,Q9NRK6,P08195,Q9UBX3 15 +Metal dependent deubiquitinase activity 0.7156861317865896 1.525571166000787 0.1271166975870965 1.0 0.3857034043224915 7 O00487 1 +Aspartic type peptidase activity 0.7570980939823266 1.520825934552327 0.1283035243769372 1.0 0.386600515179415 5 Q8TCT8,P42574 2 +Phosphatidylinositol 3 4 5 trisphosphate binding 0.6696385206969521 1.5197415573697506 0.1285759425954111 1.0 0.386600515179415 9 Q9H0H5,Q9BWH2,P31749 3 +Metal ion transmembrane transporter activity 0.5204628108597011 1.5141193106547342 0.1299955817822036 1.0 0.3872611069158891 20 Q8IUH4,Q8TAD4,Q8N4V1,Q8NE86 4 +Cysteine type endopeptidase activity involved in apoptotic signaling pathway 0.7324909747292392 1.513583440689905 0.1301315236290681 1.0 0.3872611069158891 2 P42574 1 +Membrane insertase activity 0.7126746020951162 1.5128221136042153 0.1303248501218354 1.0 0.3872611069158891 7 Q15070,Q8N4V1 2 +Sphingolipid binding 0.712200854830525 1.510815781322901 0.1308353927804622 1.0 0.3872611069158891 7 Q9Y5P4 1 +Nad retinol dehydrogenase activity 0.7296028880866399 1.5002041138278177 0.1335615379668464 1.0 0.3909763963831253 2 Q8TC12 1 +Oxidoreduction driven active transmembrane transporter activity 0.494219497514921 1.4984735217687786 0.1340102670006666 1.0 0.3911651886909788 26 P13073,O75306,P28331,Q9UDW1,P51970,O75489,P19404,O43676,P00403,O95182,Q16795,O75251,Q16718,P56556 14 +Protein serine threonine kinase inhibitor activity 0.6851671714898112 1.4975676014467434 0.1342456295870391 1.0 0.3911651886909788 8 P04792,Q9Y3B8,P42771,P42574 4 +Sphingolipid transfer activity 0.8945668581516418 1.4938684922952854 0.135209995128013 1.0 0.3923451605352168 3 Q9Y5P4 1 +S adenosylmethionine dependent methyltransferase activity 0.4298537621888181 1.490353041638263 0.1361314326865357 1.0 0.3941583312427145 38 P22061,Q7L592,Q03164 3 +Damaged dna binding 0.4841091412259709 1.483960042300992 0.1378195214143134 1.0 0.3942928784726692 28 O94761,P35244 2 +Proton channel activity 0.6198326677634775 1.483438273857176 0.1379580048832138 1.0 0.3942928784726692 11 P00846 1 +Proton transporting atp synthase activity rotational mechanism 0.6198326677634775 1.483438273857176 0.1379580048832138 1.0 0.3942928784726692 11 P00846 1 +Palmitoyltransferase activity 0.7470600098542942 1.4808420876042188 0.1386486582425548 1.0 0.3954164523698611 5 Q8IUH4,P23786 2 +Structural constituent of ribosome 0.3622819578368718 1.466605548825485 0.1424833897086173 1.0 0.4046162925699837 105 P62906,P47914,Q9Y3D9,P18077,Q6P1L8,Q8N5C6,P52815,P62249,P62910,Q9Y3U8,P62899,Q9Y2R5,P62753,P62424,P49406,P62841,Q9NRX2,P32969,P63173,P62263,P62081,P15880,P30050,P82673,P62241,Q9H9J2,Q13084,P35268,P82675,P62244,P62829,P62269,Q9BYD2,P39019,P62750,P61247,O95182,P08865,P62277,P05388,P46781,P61353,P42766,P18124,P26373,Q9Y2Q9,P05387 47 +3 5 exodeoxyribonuclease activity 0.723105961947643 1.4577055604697169 0.1449217186345714 1.0 0.4071901988696522 6 Q07864 1 +Organic hydroxy compound transmembrane transporter activity 0.8834838559915371 1.453058299869931 0.1462075677622705 1.0 0.4095396364996076 3 Q14728 1 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen nad p h as one donor and incorporation of one atom of oxygen 0.8806602685344753 1.4426558753129963 0.149117434910571 1.0 0.4096478437714788 3 Q16850 1 +Atpase binding 0.4821502376178643 1.4424090045017977 0.149187025120689 1.0 0.4096478437714788 27 Q92542,Q9NWS0,Q08209,O76024,Q9BUN8,Q04323,P60520,Q5JTV8,Q9UII2 9 +Minor groove of adenine thymine rich dna binding 0.8542644046792536 1.4065065606802698 0.1595737578225986 1.0 0.430169420174916 4 Q03164,P17096 2 +Ubiquitin specific protease binding 0.6871110512974191 1.4042988299802952 0.1602298825550114 1.0 0.4310637933514377 7 Q9BUN8 1 +Hsp70 protein binding 0.5336588114019358 1.3948813090644652 0.1630516343355492 1.0 0.4340442794858348 15 Q9UNE7,Q96EY1 2 +Atpase coupled transmembrane transporter activity 0.4908054268650548 1.3907716870623978 0.1642946712822994 1.0 0.4340917708758267 22 O15439,P33527,O75027 3 +Alpha tubulin binding 0.6839317732893352 1.390770341066935 0.164295079571513 1.0 0.4340917708758267 7 Q9P265 1 +Anion transmembrane transporter activity 0.4176898882062606 1.3838697531970994 0.1663983398026156 1.0 0.4370422798373047 38 Q8TB61,Q9BQT8,Q9C0H2,Q9H2D1,P33527,O15439,Q14728,Q9UBX3 8 +Phosphatidylinositol 4 phosphate binding 0.6541311913662293 1.3607820594956168 0.17358257308448 1.0 0.4523357639789684 8 Q9Y5P4 1 +Amyloid beta binding 0.6503747631325347 1.3441852514382608 0.1788884896774996 1.0 0.4563201588894375 8 O15212,Q8WTV0 2 +Molecular function activator activity 0.5690676039643872 1.3334334582522185 0.1823895986531143 1.0 0.4593086572240621 12 Q5JTV8,P31749 2 +Phospholipid transfer activity 0.8341199923234215 1.3324463364562609 0.1827135643789994 1.0 0.4593086572240621 4 Q9Y5P4 1 +Efflux transmembrane transporter activity 0.8505946865736904 1.3318270883117864 0.1829170144495966 1.0 0.4593086572240621 3 P33527 1 +Abc type xenobiotic transporter activity 0.8505946865736904 1.3318270883117864 0.1829170144495966 1.0 0.4593086572240621 3 P33527 1 +Nucleotidyltransferase activity 0.4106153423509495 1.3228729541370017 0.1858776308725445 1.0 0.4593086572240621 39 O95674,P19388,Q07864 3 +Lysophospholipase activity 0.6887788284975005 1.316644433074665 0.1879578375576893 1.0 0.4633198542888287 6 Q8NCC3 1 +Atpase coupled inorganic anion transmembrane transporter activity 0.8459444265860139 1.3146855165622056 0.1886156161578973 1.0 0.4633198542888287 3 P33527 1 +Growth factor receptor binding 0.5218041061637653 1.3032940397725137 0.1924743951531398 1.0 0.4689156142144232 14 O14745,Q9NZ08,Q9Y639,Q13596 4 +Monocarboxylic acid binding 0.5002905426827052 1.3000155238524167 0.1935956486234444 1.0 0.4701958009671089 18 Q01469,O15254,P09455 3 +O methyltransferase activity 0.6387636992555656 1.29285236617837 0.196062124880624 1.0 0.4731716267714743 8 P22061 1 +Oxidoreductase activity acting on the ch ch group of donors oxygen as acceptor 0.6972418896774297 1.281569661983692 0.1999936482839046 1.0 0.4760387680819684 5 O15254,Q15067 2 +Isopeptidase activity 0.6146530693351469 1.268438597587072 0.2046413652668564 1.0 0.4822134298575392 9 O00487 1 +Beta tubulin binding 0.5107902816202192 1.264600706887055 0.2060144995464543 1.0 0.4843307695809148 15 O14737,Q9H0H5 2 +Magnesium ion transmembrane transporter activity 0.8305862986131849 1.2581041337144072 0.208354098567717 1.0 0.4866477978848786 3 Q8IUH4 1 +Proton transmembrane transporter activity 0.425135192927341 1.242611601272134 0.2140109927644657 1.0 0.4963710460453316 34 P56385,P21281,Q9UDW1,P00846 4 +Organic acid transmembrane transporter activity 0.4830843405734996 1.2352214277900069 0.2167481065699128 1.0 0.5001011000545384 19 Q9H2D1,P33527,O15439,Q9BQT8,Q9UBX3 5 +Molecular carrier activity 0.4368441379973325 1.224143152655143 0.2208982296603037 1.0 0.5041435607557467 31 Q9UI26,Q15070,Q8N4V1 3 +Gamma tubulin binding 0.6827425973450285 1.2234612607041695 0.2211555274045149 1.0 0.5041435607557467 5 Q9H0H5,Q96CW5 2 +Molecular function inhibitor activity 0.5847438980400549 1.2165405626365122 0.2237790689795216 1.0 0.5092506552633291 10 Q96ST3,P20936,Q9UII2,O43768 4 +Protein binding involved in heterotypic cell cell adhesion 0.6788716876495714 1.2079519894178647 0.2270657301177161 1.0 0.5143635075578226 5 P14923,P78310 2 +Nadh dehydrogenase activity 0.4786166797091219 1.2076370754802728 0.2271868916000314 1.0 0.5143635075578226 19 O75306,P51970,O75489,P19404,O43676,O95182,Q16795,O75251,Q16718,P56556 10 +Camp dependent protein kinase inhibitor activity 0.6653429602888048 1.202451344936469 0.2291887062758046 1.0 0.5153837405085354 2 P10644 1 +Structural constituent of synapse 0.6359104388418018 1.1860637480529916 0.2355971255297442 1.0 0.5288996280895778 7 P07196 1 +Histone h3 methyl lysine 4 demethylase activity 0.6581227436823066 1.1691402353364688 0.2423471354667163 1.0 0.5394963869937456 2 O60341 1 +Sphingolipid transporter activity 0.7831380057177194 1.145289888707702 0.2520890930965609 1.0 0.5492236143038188 4 Q9Y5P4 1 +Inorganic anion transmembrane transporter activity 0.4877615657295522 1.1333428141074744 0.2570703188233045 1.0 0.555522688969385 15 O15439,P33527 2 +Translation activator activity 0.777837591831104 1.1259071601280513 0.2602048183262315 1.0 0.5604452811556091 4 Q9H074,P11940 2 +Protein phosphatase 1 binding 0.6546446027601311 1.111013984260401 0.2665623299926993 1.0 0.5659314947065373 5 O95793 1 +Oligosaccharyl transferase activity 0.7680635838150207 1.0902286801115646 0.2756124226786487 1.0 0.5753127027029183 4 Q8TCJ2,P04844,P04843 3 +Dolichyl diphosphooligosaccharide protein glycotransferase activity 0.7680635838150207 1.0902286801115646 0.2756124226786487 1.0 0.5753127027029183 4 Q8TCJ2,P04844,P04843 3 +Structural constituent of eye lens 0.7839459524252845 1.0870236466918586 0.2770263593540352 1.0 0.5761628037269371 3 Q99797 1 +Gtpase binding 0.3371485056400601 1.0828753498881472 0.2788637545397445 1.0 0.5774485494416693 82 Q96KP1,Q9H4M9,P20936,Q8TEY7,O75116,Q01968,P50748,Q9NSV4,Q96S59,Q9UI26,Q9Y333,Q6IAA8,P53365,O43592,Q8IWJ2,Q96A65,Q9Y3P9,O15397 18 +Pyrophosphate hydrolysis driven proton transmembrane transporter activity 0.5909739427786361 1.0817074172816763 0.2793825562761425 1.0 0.5774485494416693 8 P21281,P21283,P36543 3 +Atpase coupled ion transmembrane transporter activity 0.5909739427786361 1.0817074172816763 0.2793825562761425 1.0 0.5774485494416693 8 P21281,P21283,P36543 3 +Atp dependent dna dna annealing activity 0.7622434520412138 1.0690280996286556 0.2850570078618815 1.0 0.5864408102917036 4 P46100 1 +Organic cation transmembrane transporter activity 0.6398929523711444 1.0521881807877138 0.2927132210433563 1.0 0.5976678757274424 5 Q70HW3 1 +Oxidoreductase activity acting on paired donors with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 0.7740833055877681 1.0511002877349562 0.2932125319595879 1.0 0.5976678757274424 3 O00767 1 +Phosphatase activator activity 0.6292418772563135 1.0367127646837588 0.2998697413067939 1.0 0.6047448955944296 2 Q14738 1 +Protein phosphatase activator activity 0.6292418772563135 1.0367127646837588 0.2998697413067939 1.0 0.6047448955944296 2 Q14738 1 +Protein phosphatase regulator activity 0.4683700155689938 1.0232245449981827 0.3062016902716731 1.0 0.6133210509162514 15 Q9UQ13,O43768,Q86XL3 3 +Iron ion binding 0.4415457008035633 1.0166462483660583 0.3093217447247682 1.0 0.6163611764121805 20 Q16850,Q9BU89,Q15800,Q6UW02 4 +Transcription regulator inhibitor activity 0.7475360582843403 1.0156337817564232 0.3098038117707573 1.0 0.6163611764121805 4 Q96ST3 1 +Glycolipid binding 0.5397731107967256 1.0033916156926856 0.3156719478477203 1.0 0.6258259240290729 10 P55145,Q9NZD2,O14773 3 +Cis trans isomerase activity 0.4275503826611232 1.001790656100241 0.3164447110214725 1.0 0.6258259240290729 24 Q9Y237,O95302 2 +Protein serine kinase activity 0.3734453135240322 0.9968745569923018 0.3188254029424677 1.0 0.6295972667318568 41 O43318,O95747,Q14004,P31749,Q7KZI7,P31751,Q99640,P36507,Q13043 9 +Phospholipid transporter activity 0.6102113470695957 0.9940409065920546 0.320202952683406 1.0 0.6298649483101434 6 Q9Y5P4 1 +Aspartic endopeptidase activity intramembrane cleaving 0.7561808594097836 0.9862376026400322 0.3240165310545952 1.0 0.6335172524543939 3 Q8TCT8 1 +Acyl coa oxidase activity 0.7556046572496806 0.9841584303756636 0.3250376213167223 1.0 0.6335172524543939 3 O15254 1 +Transcription coregulator binding 0.428416897843207 0.9826706925724464 0.3257695393540389 1.0 0.6335172524543939 22 Q9UQB8,Q71SY5,P17096 3 +Protein serine threonine tyrosine kinase activity 0.3703199273537149 0.9771855386529196 0.3284773060477781 1.0 0.6353250137347867 45 O43318,O95747,Q14004,P31749,Q7KZI7,P31751,Q9NWH9,Q99640,P36507,Q13043 10 +Lamin binding 0.6045761061187087 0.9711191758526873 0.3314889357990176 1.0 0.6366312076255699 6 Q5JTV8 1 +Retinoic acid receptor binding 0.6016690329343383 0.9593159040850472 0.3373996257187759 1.0 0.6414937089846255 6 Q71SY5,P17096 2 +Protein methyltransferase activity 0.4185698169838689 0.957052001113923 0.3385410087227534 1.0 0.6427442865607703 25 P22061,Q7L592,Q03164 3 +Mrna 5 utr binding 0.4242636976783274 0.9470700189945462 0.3436031008167504 1.0 0.6504964686402582 21 Q9H2U1,Q9Y6M1,P62263,P62081,P19338,P34897 6 +Isoprenoid binding 0.7282267076383516 0.9460156919426224 0.3441405826338775 1.0 0.6505872465439875 4 P09455 1 +Transition metal ion transmembrane transporter activity 0.6086967544931141 0.9287040246662548 0.353042494438041 1.0 0.6636399930808438 5 Q8N4V1 1 +Protein serine threonine kinase activity 0.3610762664266188 0.916409494045218 0.3594521576019931 1.0 0.6728055442866542 50 Q9UHY1,O95747,Q14004,O43318,Q7KZI7,P31749,Q16539,P31751,Q99640,Q8IV63,Q99986,P36507,Q13043,P54619 14 +Phosphatase regulator activity 0.4448309699907039 0.9099123274949966 0.3628687480103825 1.0 0.6733292673445315 16 Q9UQ13,O43768,Q86XL3 3 +Oxygen binding 0.7330358203324575 0.903221461208964 0.3664083698750611 1.0 0.6767819352980583 3 P04179 1 +Chromatin dna binding 0.3857270450513111 0.8963862955769714 0.3700464840726645 1.0 0.681152046166996 33 P05204,Q969T9,P16403,P07305,P40763,O94842,Q9P0M6 7 +Oxidoreductase activity acting on other nitrogenous compounds as donors cytochrome as acceptor 0.7296395138901812 0.8911359832543461 0.3728562227846539 1.0 0.6834840276976621 3 O43169 1 +Nitrite reductase activity 0.7296395138901812 0.8911359832543461 0.3728562227846539 1.0 0.6834840276976621 3 O43169 1 +Carbon carbon lyase activity 0.4261190673681978 0.8858613335051274 0.3756922543793335 1.0 0.6875931487108942 19 Q16822 1 +Proteasome binding 0.4961206890061246 0.8750742459211905 0.3815335090693217 1.0 0.6921593333879482 11 O76024,O95456,O00487,P46379 4 +Signal recognition particle binding 0.5797936467321182 0.8710615897750636 0.38372052515299 1.0 0.6921593333879482 6 P08240,Q9BUN8 2 +Gated channel activity 0.5040673016440541 0.8367824187013707 0.4027148815809236 1.0 0.7174371013686964 10 Q9C0H2 1 +N methyltransferase activity 0.4169889203658655 0.8308963224522607 0.4060322013599038 1.0 0.7211866816250737 19 Q7L592,Q03164 2 +Virion binding 0.5826714801443994 0.8279317454615776 0.4077091553857186 1.0 0.7211866816250737 2 Q99816 1 +Dna n glycosylase activity 0.5809710906288752 0.8206201761331904 0.4118626515825867 1.0 0.7252628924418942 5 P13051 1 +Map kinase scaffold activity 0.6913813777460919 0.8152918514275698 0.4149052719595505 1.0 0.7264238114388375 4 P36507 1 +Long chain fatty acid binding 0.5787003610108253 0.8105315860109212 0.4176347189535838 1.0 0.7293515656889789 2 Q00169 1 +Transferase activity transferring phosphorus containing groups 0.2961702972455589 0.8080962843347202 0.4190351564423626 1.0 0.7308369067085302 145 O95674,Q13057,O95747,Q9UHY1,P19388,Q9H9Y6,Q7KZI7,Q9Y5P4,P36507,Q9BRR6,O15160,Q14004,O95602,Q12792,P54886,P19784,P30085,Q9H0P0,Q9BZX2,Q16851,Q9UKK9,P00568,O00764,O43318,P31749,Q16539,Q86U90,Q9NWH9,P31751,Q99640,Q99986,Q8IV63,Q13043,Q07864,O75116,P35790,Q8WVC6,P54619 38 +Oxidoreductase activity acting on a heme group of donors 0.5709746869240508 0.782190724793502 0.4341024946347311 1.0 0.7482778409462486 5 P13073,P10606,P00403 3 +Protein kinase activity 0.3357330883363716 0.7787363390732761 0.4361350451942241 1.0 0.7508076101853935 61 Q9UHY1,O95747,Q14004,O43318,Q7KZI7,Q12792,P31749,Q16539,P31751,Q9NWH9,Q99640,Q8IV63,Q99986,P36507,Q13043,P54619 16 +Disordered domain specific binding 0.4271605012549218 0.7773286667152552 0.4369648862109747 1.0 0.7512630449862683 14 Q9Y3C6,P04406,O94973,Q14318 4 +Polyubiquitin modification dependent protein binding 0.4751672572130914 0.7748759708928147 0.4384129522476656 1.0 0.7526182349052931 11 P55036,P46379 2 +Vitamin transmembrane transporter activity 0.5540279130812389 0.7687910678022047 0.4420173522903932 1.0 0.7550656313546691 6 P33527 1 +Active ion transmembrane transporter activity 0.3509634336824381 0.7622275067698409 0.4459242317599914 1.0 0.7597862871910622 37 O15439,P21281,P33527,Q9UDW1 4 +Protein n terminus binding 0.3457252969611212 0.7587490609523377 0.4480026825624466 1.0 0.7613754029737743 39 Q96KP1,Q15067,O14745,P51608,Q9UER7,Q96A65 6 +Map kinase activity 0.6744393127070221 0.7564276435501783 0.4493928392203024 1.0 0.7627625585233485 4 O43318 1 +Solute cation antiporter activity 0.690078456880518 0.752705293310932 0.4516270283900054 1.0 0.7655769397070373 3 O95202 1 +Calmodulin binding 0.3697513345256003 0.7490715855974416 0.4538140600516858 1.0 0.7683043131320897 32 Q8IZT6,P31749,Q99797,Q02952,Q08209,Q9UII2 6 +Metallopeptidase activity 0.3439784003379635 0.7440893899352924 0.4568223977517676 1.0 0.7706553585211827 39 O75844,O00487,O00303,Q9NZ08 4 +Lipid transfer activity 0.528859639075606 0.7380310387984564 0.4604955878117505 1.0 0.7727255507598692 7 Q9Y5P4 1 +Cell adhesive protein binding involved in bundle of his cell purkinje myocyte communication 0.6852487535640522 0.7361544797550318 0.4616366910145379 1.0 0.7736635086485762 3 P14923 1 +Cysteine type endopeptidase activity 0.3901862366088773 0.7327608216113215 0.4637043206428388 1.0 0.7751736379048212 21 Q92643,Q8TEY7,Q9Y4P1,P42574 4 +Vitamin d binding 0.5595667870036047 0.7278856430134661 0.4666835924560044 1.0 0.7762155732584013 2 P38435 1 +Rna methyltransferase activity 0.4120674320772847 0.7265607074619674 0.4674951058860321 1.0 0.7762155732584013 16 Q7Z4G4,Q96P11 2 +Proteasome activating activity 0.5428226814026577 0.7250587006557537 0.4684160193779065 1.0 0.7762155732584013 6 P62191,P62333,P43686 3 +Kinase inhibitor activity 0.402522204179018 0.7182208824638429 0.4726211040207051 1.0 0.7802651518553008 18 Q9Y3B8,P04792,Q13217 3 +Modified amino acid transmembrane transporter activity 0.661824095312739 0.7132375811804579 0.4756987547501614 1.0 0.781344301413779 4 O15439,P33527 2 +Amide transmembrane transporter activity 0.661824095312739 0.7132375811804579 0.4756987547501614 1.0 0.781344301413779 4 O15439,P33527 2 +Monocarboxylic acid transmembrane transporter activity 0.6545789953256932 0.6887112590219789 0.4910049894885115 1.0 0.7957873549149169 4 O15439 1 +Dna binding transcription factor activity 0.3809280045619806 0.6811051040166243 0.4958049877113817 1.0 0.8025880982563048 22 Q96KM6,P51608,O95747,Q99640 4 +Vitamin b6 binding 0.385833868673659 0.6750675191992961 0.4996328686531939 1.0 0.8078005869100908 20 O00764,Q8TD30,O95470 3 +Camp dependent protein kinase regulator activity 0.6655832430480263 0.6697236790838139 0.5030339539711695 1.0 0.8123112087821194 3 P10644,P54619 2 +Sulfatide binding 0.6634309698385603 0.662554606604125 0.5076158507777364 1.0 0.816805174761238 3 O14773 1 +Xenobiotic transmembrane transporter activity 0.6466730432152552 0.6622001643653462 0.5078429488906449 1.0 0.816805174761238 4 P33527 1 +Ribosomal small subunit binding 0.4353720565736026 0.6581738081067924 0.5104264529774798 1.0 0.816805174761238 12 P46199,P13051,O75616,Q96EY7 4 +Transition metal ion binding 0.2753509677486749 0.6573002810446743 0.5109878558214409 1.0 0.816805174761238 164 Q5VUA4,Q8TAD4,O00764,Q8TEY7,Q03164,P49356,Q16822,Q9NZ08,Q6UW02,Q8N4Q0,Q9Y5L4,Q15800,Q16850,Q8NCC3,Q07864 15 +Enzyme activator activity 0.2982028434970085 0.6559994267180466 0.5118244930801459 1.0 0.816805174761238 93 O43169,P20936,O00487,Q01968,Q7KZI7,Q9Y376,Q9H0H5,P36507,P42574,O14737,Q13043,Q9Y3P9,P14635 13 +Kinase binding 0.273393712119269 0.6550368582447034 0.5124440235054522 1.0 0.816805174761238 159 O95747,Q9NY61,Q9UER7,P14635,Q6IBS0,Q14004,Q9Y376,P04792,P26038,Q13217,Q96EY1,Q96KP1,Q96JJ3,O43318,P31749,P39019,Q10567,Q9H0H5,Q99986,O94973,Q13043,P56545,P14923,Q9Y3B8,Q9UNE7,P15924 26 +Metalloendopeptidase activity 0.4030790335118082 0.6495992055121171 0.515951146413401 1.0 0.8202142028509689 14 O75844,Q96TA2 2 +Nadph binding 0.6408854809990404 0.6429703704494595 0.5202433259283819 1.0 0.8250636994735316 4 Q9UBQ7,P00374 2 +Transferase activity transferring nitrogenous groups 0.4736841689729392 0.6378505741366681 0.5235709543753893 1.0 0.8263006148688269 9 P04406,P17174,Q8TD30,O15382 4 +Microtubule motor activity 0.4123402132832016 0.6190765295501107 0.5358659442563711 1.0 0.8350836054435914 13 O00139,Q02241,Q99661,Q12756 4 +Protein folding chaperone 0.3648753978253258 0.6058620933473201 0.5446063328988038 1.0 0.8435685506089862 25 P04792,O75190 2 +Fad binding 0.465679636343574 0.604434468516494 0.5455548252805493 1.0 0.8438133734895539 9 Q15392,O15254 2 +Nuclear receptor coactivator activity 0.3811378089136649 0.5981616511791149 0.5497320768544287 1.0 0.8475567635029417 18 O75448,P41223,Q9H7N4,P35609,P17096 5 +Cysteine type endopeptidase activity involved in apoptotic process 0.6417600462103835 0.5916315512063265 0.5540973412940866 1.0 0.8518358391972914 3 P42574 1 +Calcium ion transmembrane transporter activity 0.4211470178822357 0.5911343596091857 0.5544303994775448 1.0 0.8518358391972914 12 O95202,Q8NE86 2 +Camp dependent protein kinase activity 0.6408732079155677 0.5887814185369934 0.5560079122424577 1.0 0.8522889450636982 3 P54619 1 +Cyclic nucleotide dependent protein kinase activity 0.6408732079155677 0.5887814185369934 0.5560079122424577 1.0 0.8522889450636982 3 P54619 1 +Protein macromolecule adaptor activity 0.2904666493332898 0.5856919000644483 0.5580825782581131 1.0 0.8535002836651695 85 Q9UQB8,Q86VM9,P14923,Q9P253,P07196,Q92542,O14745,Q86YP4,P40763,P36507,O00161,O94901,P18074,O95721,O94973,P62333,Q9UNE7,O15498 18 +Transferase activity transferring one carbon groups 0.3208976282948941 0.576936290461667 0.5639824940975158 1.0 0.8585712882652904 54 Q7L592,Q96P11,Q03164,Q7L2J0,P22061,Q7Z4G4,Q52LJ0 7 +Phosphatidylinositol bisphosphate phosphatase activity 0.6339102203663536 0.5665577617691873 0.5710146787484363 1.0 0.8649583440575259 3 Q01968 1 +Atpase activator activity 0.4294930312132159 0.5654212216420197 0.5717872934731907 1.0 0.8649583440575259 11 Q5JTV8,O75190 2 +Dopamine receptor binding 0.4996786804351449 0.5625103891515486 0.5737683272367076 1.0 0.8655370112344885 6 O14745 1 +Protein phosphatase binding 0.3201181956885642 0.552526072400094 0.5805879764327955 1.0 0.8748315427201646 38 O95793,Q16539,O43768,P14923,Q9NWH9,Q9UQ13,Q8IV63,P40763,Q86XL3 9 +Beta catenin binding 0.4249118891734421 0.5453444264224757 0.585516654410785 1.0 0.8766129073074643 11 P78310 1 +Molecular adaptor activity 0.2924071690293321 0.5449186002180167 0.5858095030104895 1.0 0.8766129073074643 106 Q9UQB8,P07196,Q6IAA8,P36507,Q14141,Q9P253,Q92542,Q86YP4,Q86VM9,P18074,O95456,O15498,P40763,O95721,O94973,P62333,P14923,Q9BT73,O14745,O00161,O94901,Q9UNE7 22 +K48 linked polyubiquitin modification dependent protein binding 0.6102686706363067 0.5440785577949141 0.5863874150461519 1.0 0.8766129073074643 4 Q92890,Q04323 2 +Carbon sulfur lyase activity 0.4890915849943649 0.5244038386798663 0.5999976871703394 1.0 0.8901702394009591 6 Q7Z7K6 1 +Small ribosomal subunit rrna binding 0.6029733767685856 0.5213050475167512 0.6021542853434629 1.0 0.8901702394009591 4 P62263,Q14011 2 +O acyltransferase activity 0.4500412848494385 0.4926958155604946 0.6222275347395061 1.0 0.9037599930806596 8 P23786,Q8NCC3 2 +Kinase activity 0.2863616464738464 0.4786070803586858 0.6322181803802798 1.0 0.9132803931797736 103 Q13057,O00764,O95747,Q9UHY1,O43318,P31749,Q7KZI7,Q9NWH9,P35790,P31751,Q9Y5P4 11 +Map kinase kinase activity 0.4754469796737623 0.4765698651240277 0.6336684463013478 1.0 0.9143815039462444 6 Q16539,P36507 2 +Hydrolase activity hydrolyzing n glycosyl compounds 0.4597542978574097 0.4733457092766348 0.6359665562539285 1.0 0.9167023354245888 7 P13051 1 +Carbon nitrogen lyase activity 0.5852958740498686 0.4675667729353151 0.6400944309297976 1.0 0.9216527613279534 4 O75223 1 +Modification dependent protein binding 0.309441513150805 0.4624098010986951 0.6437874720822383 1.0 0.9244134439208296 41 P55036,P42695,Q03164,P46379,P46100 5 +Metalloexopeptidase activity 0.3519019536158407 0.4610063804211503 0.6447940274752513 1.0 0.9244134439208296 19 O75844 1 +Peptidase activator activity 0.4042221488819532 0.4574536717485685 0.6473449943218477 1.0 0.926072656032008 11 O00487,Q14997 2 +4 iron 4 sulfur cluster binding 0.3538102766771495 0.4531441813952596 0.6504449230716993 1.0 0.9271498474813696 18 O75306,Q8TB37,O75251,P18074,Q07864 5 +Malate dehydrogenase activity 0.4786766602370324 0.4505918346253182 0.6522837527427243 1.0 0.9271498474813696 5 P23368,P40925 2 +Exopeptidase activity 0.3290756340287429 0.4495417755017697 0.6530408792044429 1.0 0.9272343252806672 31 O75844,Q9NZ08,O14773 3 +Serine type endopeptidase inhibitor activity 0.5773121387283298 0.4440198301685593 0.6570282469536544 1.0 0.9299153782762584 4 P50454,P07355,P35237 3 +Ubiquitin like protein specific protease activity 0.327637792827307 0.4404005350614731 0.6596470374552099 1.0 0.931637526862884 31 O00303,O00487,Q9Y4P1 3 +Protein homodimerization activity 0.2657799968568445 0.4296795252864537 0.6674287792740361 1.0 0.9357842688803516 151 Q5VUA4,O00764,Q9UHY1,Q03164,O75027,P31749,P51648,P14923,Q15102,P09601,Q8TCT8,Q04837,P04792,Q15070,Q9UII2,Q13043,Q9UNE7 17 +Phosphatidylinositol phosphate phosphatase activity 0.5695491202781062 0.4215873545466738 0.6733262379162468 1.0 0.9429405376087376 4 Q01968 1 +Mhc class i protein binding 0.4440325258747745 0.4184156958049835 0.6756432127294882 1.0 0.9430301967946731 7 Q9BUN8 1 +Organophosphate ester transmembrane transporter activity 0.3943905194735523 0.4174935961958695 0.6763174073533689 1.0 0.9430301967946731 11 O15439,Q8TB61,Q9H2D1 3 +Nucleotide transmembrane transporter activity 0.3943905194735523 0.4174935961958695 0.6763174073533689 1.0 0.9430301967946731 11 O15439,Q8TB61,Q9H2D1 3 +Exogenous protein binding 0.3539785403225629 0.4166449103536365 0.6769381548097202 1.0 0.9430301967946731 15 Q8WTV0 1 +General transcription initiation factor binding 0.3520639877329869 0.407769269590042 0.6834430767482433 1.0 0.9481167526079493 15 Q86VP6,O15160,Q14978,P42345,O60869,Q00839,O95999,P62191 8 +Ubiquitin like protein conjugating enzyme activity 0.4396529966103063 0.4035639236984427 0.6865334191215351 1.0 0.9514107549661316 7 Q16763,P61088 2 +Channel inhibitor activity 0.4597822088730647 0.3903276697577007 0.6962942652520983 1.0 0.9551221952573116 5 O43768 1 +Structural molecule activity 0.2686873187764754 0.3901868969116018 0.6963983500408841 1.0 0.9551221952573116 201 P68371,P04350,P62906,P07196,Q9Y3D9,P18077,Q6P1L8,Q8N5C6,P35609,P52815,P62249,P62910,Q9Y3U8,P62899,P62753,Q9Y2R5,P62424,P62841,P36551,O15145,Q9NRX2,P32969,P62263,P62081,P15880,P26038,P30050,Q14651,Q9BVL2,P82673,P62241,Q5SRE5,P17096,Q13084,Q9UPN3,P35268,P82675,P62244,P62269,Q9BYD2,P39019,Q9Y5K6,P61247,P62750,P08865,P05388,O75116,P07197,P61353,P42766,P56545,P14923,Q9Y490,Q99797,Q15149,P09601,Q14152,P18124,Q13885,Q9Y2Q9,Q96CW5,P58107,P05387,P15924 64 +Quinone binding 0.5579626736823069 0.3890048518358395 0.6972725572751655 1.0 0.955335287235768 4 O75306 1 +Rna polymerase ii specific dna binding transcription factor binding 0.2815111653924739 0.3749215887445779 0.7077187827613491 1.0 0.960733669346101 76 Q06265,Q969T9,O75448,P56545,Q96ST3,P04792,P28370,Q96HY6,Q71SY5,Q9UER7,Q13043,P17096 12 +Nucleobase containing compound transmembrane transporter activity 0.3568688461243205 0.3651201438403437 0.7150217247991051 1.0 0.9611559340906768 13 O15439,Q8TB61,Q9H2D1 3 +Thioesterase binding 0.4599277978339282 0.3477274044214619 0.7280449137663634 1.0 0.972962511327058 2 P60953 1 +Sh3 domain binding 0.3521339961141514 0.3456021924807924 0.7296416980350124 1.0 0.972962511327058 13 Q14195,Q96JJ3,Q96PU8,Q9Y5K6,Q96T51,Q68EM7,P50570 7 +Epidermal growth factor receptor binding 0.4434789725285087 0.3411989625699795 0.7329538042266852 1.0 0.976047701219704 5 P18085,Q13596 2 +Channel regulator activity 0.3365105347357713 0.3382222526307269 0.7351957078026516 1.0 0.977299965846767 15 P20936,O14745,O43768,P31749 4 +Acyltransferase activity 0.2923011509962451 0.3298272743342831 0.741530477584389 1.0 0.977299965846767 46 Q96G23,O75448,Q8IUH4,P68402,Q15102,P23786,Q8NCC3,O15498 8 +Phosphatase binding 0.2920955632759597 0.3283612993534054 0.7426385008431435 1.0 0.977299965846767 46 O95793,Q16539,O43768,P14923,Q9NWH9,Q9UQ13,Q8IV63,O14745,P40763,Q86XL3 10 +Primary mirna binding 0.5500339264770103 0.3255621811531716 0.7447556295880515 1.0 0.9780437072356922 3 P40763 1 +Ligase activity 0.2659880324478038 0.3206800148112264 0.7484528939324651 1.0 0.9796932454299578 85 P18858,Q8TBC4,Q9HCC0,P00846,Q5JPH6 5 +Rna polymerase ii general transcription initiation factor binding 0.3990465016768487 0.3152759729451075 0.7525521262583401 1.0 0.982004235623253 8 Q00839,Q14978 2 +Tbp class protein binding 0.4300686664257139 0.3029972454328019 0.7618919608157559 1.0 0.9856021028020648 5 Q86VP6,P62191,P62195,Q9Y265 4 +Nuclear receptor binding 0.2955735167497935 0.3023609151659323 0.762376946335984 1.0 0.9856021028020648 35 Q969T9,O75448,P56545,Q71SY5,P17096 5 +Nucleocytoplasmic carrier activity 0.3201248068188587 0.2930154258939011 0.7695103607761864 1.0 0.9875293716719736 18 Q9UI26 1 +Rna polymerase ii activity 0.4400722021660582 0.2866614933145934 0.7743715245320912 1.0 0.988175947918074 2 P24928 1 +Oxidoreductase activity acting on other nitrogenous compounds as donors 0.512244738582127 0.2722479027696218 0.7854314112361873 1.0 0.9945590691140098 4 O43169 1 +Mitogen activated protein kinase p38 binding 0.526146604228648 0.2681729348184552 0.7885662070872548 1.0 0.9945590691140098 3 Q15750 1 +Structural constituent of cytoskeleton 0.2983865601786527 0.2679180208453965 0.7887624220061447 1.0 0.9945590691140098 31 P68371,P04350,P07197,O15145,Q9Y490,Q15149,P07196,Q13885,P26038,Q96CW5,Q14651,P15924 12 +Translation regulator activity 0.2676397810169622 0.2637324349390313 0.7919861006348212 1.0 0.9948119722853316 78 O00303,P35268,P00374,Q14197,Q9Y6M1,Q04637,P62263,Q14152,P46199,Q9H074,O43583,Q7L2H7,P11940,Q9ULC4,O75822,Q8NE71,Q7Z478,P51116 18 +Peptide binding 0.273257335374476 0.2582639938570897 0.7962031725739553 1.0 0.995441219520966 66 Q15392,Q9Y3C6,Q9NZ08,Q8WTV0,O14773 5 +Rna polymerase iii transcription regulatory region sequence specific dna binding 0.427436823104686 0.2510881977042433 0.8017459205464159 1.0 1.0 2 P42345 1 +Dicarboxylic acid transmembrane transporter activity 0.3760121741855525 0.2463607179625851 0.8054030117639297 1.0 1.0 8 Q9BQT8 1 +Peptidase activity 0.2656184537767678 0.2388369931616092 0.8112319837892055 1.0 1.0 109 O75844,Q92643,Q8TEY7,O00487,P49721,Q9NZ08,Q8TCT8,Q96TA2,P42785,P81605,O00303,Q13867,P42574,Q13043,Q9Y4P1,O14773 16 +Phosphatidylglycerol binding 0.5104828951169279 0.2337733636498232 0.8151609293745175 1.0 1.0 3 Q9UJZ1 1 +Protein domain specific binding 0.2472261367959448 0.2191972245860755 0.8264964173761584 1.0 1.0 166 Q9UQB8,Q14195,Q9NY61,Q96PU8,Q9Y3C6,Q9NRX2,P78310,P07196,P35609,P80723,P46100,P20645,P53365,P36507,P51608,O94973,Q96A65,Q9UNE7 18 +Nucleosomal dna binding 0.2938722041772322 0.2138805246273687 0.8306402279171474 1.0 1.0 21 P05204,P07305,P16403 3 +Nucleosome binding 0.2861911776963434 0.2122761596757428 0.8318915934289906 1.0 1.0 32 P05204,P16403,P07305,Q9UGN5,P28370 5 +Modified amino acid binding 0.2917903230063166 0.2051343187112294 0.8374671840768197 1.0 1.0 21 Q8WTV0 1 +Purine nucleotide transmembrane transporter activity 0.3520489462254508 0.2048412797622118 0.8376961341999696 1.0 1.0 9 O15439,Q8TB61 2 +Microtubule minus end binding 0.3870644455223428 0.1957399995556801 0.8448136748392743 1.0 1.0 5 Q9BSJ2,Q96CW5 2 +Ubiquitination like modification dependent protein binding 0.4743002861029438 0.1917159358270234 0.8479647225529314 1.0 1.0 4 Q9UER7 1 +Threonine type endopeptidase activity 0.3549635184846298 0.1907056497148436 0.848756212099288 1.0 1.0 8 P49721 1 +Tfiid class transcription factor complex binding 0.3763557483730971 0.1887075878752406 0.85032200417855 1.0 1.0 6 Q9Y2X3,Q9Y230,Q9Y265,P22087,O60869 5 +Nucleoside kinase activity 0.4695198463032735 0.1827212370948781 0.8550167514974027 1.0 1.0 4 P30085 1 +Protein disaggregase activity 0.4685693641618598 0.180964407849697 0.8563955131401952 1.0 1.0 4 P11142,Q9UN37,P0DMV9 3 +Protein disulfide isomerase activity 0.3335973254607577 0.1789618639504843 0.8579676463704058 1.0 1.0 10 Q9BS26 1 +Cysteine type peptidase activity 0.2669537353875842 0.1709566382482195 0.8642578612383938 1.0 1.0 43 Q92643,Q8TEY7,O00487,P42574,O00303,Q9Y4P1 6 +Dna helicase activity 0.2758044103159763 0.1690100033852857 0.8657887730295795 1.0 1.0 33 O94761,Q2NKX8,P46100 3 +S100 protein binding 0.3451519536902893 0.1673263931176626 0.867113238179682 1.0 1.0 8 P50995,Q9HB71,P46940,P07355,P31949,Q09666,P15311 7 +Oxidoreductase activity acting on single donors with incorporation of molecular oxygen 0.4750307781081535 0.166025717469524 0.8681367114234826 1.0 1.0 3 O00625 1 +Sequence specific dna binding 0.2584233667465673 0.162410129429674 0.8709828946079161 1.0 1.0 120 Q9P0M6,Q969T9,O95747,Q03164,Q9H2U1,Q14789,Q9NWH9,Q13951,Q96KM6,Q99640,Q86YP4,P80723,P58546,P51608,P17096 15 +Snrnp binding 0.3637271236201946 0.1614752675174882 0.8717190893831495 1.0 1.0 6 P62314 1 +Trna binding 0.2610554104402018 0.1501911075416634 0.88061384147116 1.0 1.0 39 P05455,Q7Z4G4,P49589,Q86U90,Q9Y2Z4,Q5JTZ9,P18077,O43592,Q9Y606,Q5JPH6 10 +G protein coupled receptor activity 0.382310469314073 0.1467275852058791 0.883347044404478 1.0 1.0 2 O43813 1 +Cyclosporin a binding 0.3357138627892243 0.1464315380894581 0.8835807318404132 1.0 1.0 8 Q9Y3C6 1 +Metal cluster binding 0.2728987013993941 0.136344114084745 0.8915492514767178 1.0 1.0 28 O75306,Q06203,P28331,Q6FI81,O95239,Q8TB37,P19404,O75251,P18074,Q9H1K1,Q07864 11 +Dna binding bending 0.3506869125090218 0.1359271367594094 0.8918788825372401 1.0 1.0 6 P26583,Q12948,P09429,Q00059,O15347 5 +Single stranded dna binding 0.2611358043856446 0.1335504055784074 0.893758103366296 1.0 1.0 56 Q9H2U1,O94761,Q04837,P35244,P46100 5 +Ubiquitin like protein ligase binding 0.2510952879620856 0.133529392247946 0.8937747207476194 1.0 1.0 98 O95140,O95429,Q14527,Q9UER7,Q9BUN8,P61088,P46379,Q04323,P60520,Q96HY6,Q92783,Q9UNE7,P14635 13 +Macrolide binding 0.3387250758450412 0.1319741406307541 0.8950047456030428 1.0 1.0 7 Q9Y680 1 +Fk506 binding 0.3387250758450412 0.1319741406307541 0.8950047456030428 1.0 1.0 7 Q9Y680 1 +Vitamin binding 0.260107358803254 0.1310185483282577 0.8957606344412246 1.0 1.0 44 O00764,P00374,Q8TD30,P09455,P22033,O95470 6 +Ubiquitin protein transferase inhibitor activity 0.3274511212782249 0.1294414509856236 0.8970083504058703 1.0 1.0 8 P62841 1 +Hydro lyase activity 0.2754517976783883 0.1190636962159633 0.9052248923217304 1.0 1.0 14 P07954,P55084,P61457 3 +Amide binding 0.2502073562397585 0.1189133337512952 0.905344017912764 1.0 1.0 100 Q15392,Q9Y680,Q9Y3C6,P00374,Q9NZ08,P30533,Q9NZD2,Q9Y5P4,Q08209,Q8WTV0,Q9Y584,O15212,P52294,O14773 14 +Double stranded rna binding 0.2556076023016652 0.1126225342971951 0.9103298189255432 1.0 1.0 37 P68371,Q9H2U1,O95793,Q86U90,P02786,Q86UE4,P26038,Q00839,P08195 9 +Small protein activating enzyme binding 0.4348140122788004 0.1067371527612215 0.914997507316924 1.0 1.0 3 Q9UBT2,Q9UBE0 2 +Phosphatidylinositol 4 5 bisphosphate binding 0.2852762124856064 0.1020246164190658 0.9187371359561728 1.0 1.0 12 Q12792,Q6IBS0,P35609 3 +1 4 alpha oligoglucan phosphorylase activity 0.4283134705669897 0.0988898123486494 0.9212257578245078 1.0 1.0 3 P11216,P06737 2 +Mrna 3 utr au rich region binding 0.2752466434369556 0.0973287682041662 0.9224653107258054 1.0 1.0 13 Q06265 1 +Secondary active transmembrane transporter activity 0.2644390177113594 0.092286887102152 0.9264701064842188 1.0 1.0 17 O95202,Q8NE86 2 +C3hc4 type ring finger domain binding 0.4221740700613939 0.0919080601248357 0.9267710875160876 1.0 1.0 3 P11142,P0DMV9 2 +3 hydroxyacyl coa dehydrogenase activity 0.323258665344046 0.0908109228365441 0.927642830746992 1.0 1.0 6 P55084 1 +Transmembrane transporter binding 0.2592449428345859 0.0861059632926132 0.9313821832115272 1.0 1.0 28 Q9Y639 1 +Rrna binding 0.2487674400033424 0.0857948092885622 0.9316295328530464 1.0 1.0 40 P46781,P62829,O75616,P62269,Q8TDN6,P32969,P62750,P62263,Q8TCT8,Q14011,P30050,Q9NZM5,Q92552,Q96EY7,P62277,P05388,Q9Y2R5 17 +Amino acid transmembrane transporter activity 0.3023331272672135 0.0852973845360813 0.9320249707946436 1.0 1.0 8 O14745,Q9Y619,P08195 3 +Electron transfer activity 0.2518264823578143 0.0823423320766355 0.9343744925643992 1.0 1.0 48 O75489,Q9UDW1 2 +Phosphatidylcholine binding 0.2876266280752513 0.0645968335808864 0.9484950058826074 1.0 1.0 8 Q00169,O43633,P21796,A0FGR8,Q14108,P48739,Q9BSJ8 7 +Death domain binding 0.3162454873646141 0.0581035461210688 0.9536661497712328 1.0 1.0 2 Q07812 1 +Bh3 domain binding 0.3162454873646141 0.0581035461210688 0.9536661497712328 1.0 1.0 2 Q07812 1 +Type i transforming growth factor beta receptor binding 0.3838931022029607 0.0572559745161712 0.9543412900336012 1.0 1.0 3 P62942,Q9UNH7 2 +Transforming growth factor beta receptor binding 0.3838931022029607 0.0572559745161712 0.9543412900336012 1.0 1.0 3 P62942,Q9UNH7 2 +Muscle alpha actinin binding 0.3790428919931375 0.0538792399401976 0.9570313767642566 1.0 1.0 3 Q8WX93 1 +Alpha actinin binding 0.3790428919931375 0.0538792399401976 0.9570313767642566 1.0 1.0 3 Q8WX93 1 +Actinin binding 0.3790428919931375 0.0538792399401976 0.9570313767642566 1.0 1.0 3 Q8WX93 1 +C acetyltransferase activity 0.2857142857142801 0.0536959030093518 0.9571774470195632 1.0 1.0 7 P42765,P09110,P24752,Q9BWD1,O75600,P35610 6 +Enzyme regulator activity 0.2455171878000941 0.0507448078392428 0.9595288711281724 1.0 1.0 208 Q7KZI7,P80303,P14635,P62841,Q9Y376,P04792,Q13217,Q96EY1,P20936,O00487,Q01968,P31749,O43768,Q9H0H5,Q9UII2,Q13043,O43169,O14737,Q9Y3B8 19 +Acetyl coa c acetyltransferase activity 0.2856109906001397 0.0472104370618092 0.9623455092262936 1.0 1.0 6 P42765,P09110,P24752,Q9BWD1,P35610 5 +Glucosidase activity 0.2804481387784607 0.0425051461792777 0.9660960094018768 1.0 1.0 5 P35573,P04062,Q13724,P10253 4 +C4 dicarboxylate transmembrane transporter activity 0.2754880694143073 0.0387833569185374 0.969063114106106 1.0 1.0 6 O75746,Q02978,Q9UJS0,Q15758,Q9UBX3 5 +Copper chaperone activity 0.3481401227880085 0.0369508768553596 0.9705241735564936 1.0 1.0 3 O75880,Q99497 2 +Metallochaperone activity 0.3481401227880085 0.0369508768553596 0.9705241735564936 1.0 1.0 3 O75880,Q99497 2 +Calcium channel regulator activity 0.3388728323699492 0.0361764138622382 0.9711416926874904 1.0 1.0 4 Q9P246,P62942,P62258 3 +P type calcium transporter activity 0.3445287107258922 0.0354381321475211 0.9717303787397392 1.0 1.0 3 P98194,P20020 2 +Transcription factor binding 0.2427018354532288 0.0339340051960393 0.9729297765699848 1.0 1.0 131 Q9UQB8,Q06265,Q969T9,O75832,O75448,Q9UFW8,P56545,Q96ST3,P04792,P28370,Q96HY6,Q71SY5,Q9UER7,Q13043,P17096 15 +Vascular endothelial growth factor receptor binding 0.2736462093862742 0.0336059790684987 0.9731913543557142 1.0 1.0 2 Q9Y5K6 1 +Neutral amino acid transmembrane transporter activity 0.3387117583538529 0.0331822207379046 0.97352927611073 1.0 1.0 3 P08195 1 +Kinesin binding 0.2550651230101294 0.0312036959011025 0.9751070924482554 1.0 1.0 8 O60271,A0MZ66,O43747,Q86UP2,Q96EK5,Q15334,O43663 7 +Nuclear import signal receptor activity 0.2469142570818539 0.0302768484380243 0.9758462603766368 1.0 1.0 11 Q9UI26,P52294,O00505 3 +Heat shock protein binding 0.2401581904075912 0.0289810021104718 0.9768797423496433 1.0 1.0 49 O75190,Q9UNE7,P46379,Q96EY1 4 +Pyruvate dehydrogenase activity 0.3200867052023188 0.0283522529613521 0.9773812054926794 1.0 1.0 4 P11177,P10515,P09622 3 +Syntaxin 1 binding 0.3232213795594049 0.0281712172777309 0.9775255933947202 1.0 1.0 3 P46459,O75150 2 +Oxidoreductase activity acting on the aldehyde or oxo group of donors disulfide as acceptor 0.3199711087034962 0.0272872474916571 0.9782306281099508 1.0 1.0 3 P11177,Q02218 2 +Hydroxymethyl formyl and related transferase activity 0.315028901734106 0.0266381575888227 0.9787483386941868 1.0 1.0 4 P34896,P34897,P31939 3 +Tumor necrosis factor receptor superfamily binding 0.314608204856447 0.0265024465219514 0.978856582243404 1.0 1.0 4 Q12931,P42574 2 +Atp dependent activity acting on dna 0.2381782248013225 0.0258379782748895 0.9793865696691552 1.0 1.0 46 Q9H2U1,O94761,Q14527,Q2NKX8,P46100 5 +Extracellular matrix binding 0.2968580715059536 0.0224051312557001 0.982124787230224 1.0 1.0 3 P08865,P17931 2 +Laminin binding 0.2968580715059536 0.0224051312557001 0.982124787230224 1.0 1.0 3 P08865,P17931 2 +Poly a binding 0.2373513535121687 0.0206228707530708 0.983546496121831 1.0 1.0 11 P11940 1 +Protein self association 0.228863159003274 0.0189091779491233 0.984913557906134 1.0 1.0 13 Q9Y282 1 +Ankyrin binding 0.2408811845431496 0.0174049584093335 0.98611355351682 1.0 1.0 3 Q01082,Q15149 2 +Peroxiredoxin activity 0.2339117859725215 0.0160484628663686 0.9871957288867474 1.0 1.0 6 P30041,P30048,P32119,P30044,Q99497 5 +7s rna binding 0.2302964569775815 0.014818197715088 0.9881772214980712 1.0 1.0 6 P49458,Q13868,P61011,P37108,Q9UHB9 5 +Adp binding 0.2206095791001406 0.0110090358974424 0.9912162376588116 1.0 1.0 16 P55072,P00367,P35580,P00558,P48163,P43246,Q9Y230,P53041,Q9Y265,P36776,Q9UHD1,P25705,P52701,P35579,P54619 15 +Translation initiation factor activity 0.2307904887776616 0.009083906978329 0.9927521905487164 1.0 1.0 36 O00303,Q04637,Q14152,Q7L2H7,P46199,O43583,Q9ULC4,Q7Z478 8 +Receptor tyrosine kinase binding 0.2221009858542043 0.0062542632750245 0.9950098524259594 1.0 1.0 18 Q13043,O43318 2 +L amino acid transmembrane transporter activity 0.1942133815551459 0.0052689661195134 0.9957959927338004 1.0 1.0 7 O75746,Q9Y619,Q9UJS0,Q15758,Q9H936,P08195 6 +Steroid dehydrogenase activity 0.1872421824108497 0.0042812764580106 0.9965840460489844 1.0 1.0 7 Q8NBQ5 1 +Dna binding transcription activator activity 0.2041259500542885 0.0030209216124792 0.9975896569521264 1.0 1.0 9 Q99459,P04637,P78347,Q9NXV6,Q12948,Q92766,O75569,P40763 8 +Transcription coactivator activity 0.2324291642059788 0.0010825182404341 0.999136275577862 1.0 1.0 72 Q969T9,O75448,P56545,P14923,Q96ST3,P61457,Q13951,P35609,P17096 9 +Flavin adenine dinucleotide binding 0.2270980020311134 0.0010053650859738 0.999197834855064 1.0 1.0 26 Q15392,Q15067,O15254 3 diff --git a/msigdb_gomf/selections.json b/msigdb_gomf/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..57c755668b5d078ed92bfd9e6c1994bcf50fa647 --- /dev/null +++ b/msigdb_gomf/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1 4 alpha oligoglucan phosphorylase activity", "1 acylglycerophosphocholine o acyltransferase activity", "1 alkyl 2 acetylglycerophosphocholine esterase activity", "1 phosphatidylinositol 3 kinase activity", "1 phosphatidylinositol 4 kinase activity", "1 phosphatidylinositol 4 phosphate 3 kinase activity", "1 phosphatidylinositol binding", "14 3 3 protein binding", "17 beta hydroxysteroid dehydrogenase nadplus activity", "17 beta hydroxysteroid dehydrogenase nadpplus activity", "2 acylglycerol 3 phosphate o acyltransferase activity", "2 acylglycerol o acyltransferase activity", "2 iron 2 sulfur cluster binding", "2 oxoglutarate dependent dioxygenase activity", "3 5 dna helicase activity", "3 5 exodeoxyribonuclease activity", "3 5 exonuclease activity", "3 beta hydroxy delta5 steroid dehydrogenase activity", "3 hydroxyacyl coa dehydratase activity", "3 hydroxyacyl coa dehydrogenase activity", "3 phosphoadenosine 5 phosphosulfate binding", "4 iron 4 sulfur cluster binding", "5 3 dna helicase activity", "5 3 exodeoxyribonuclease activity", "5 3 exonuclease activity", "5 deoxyribose 5 phosphate lyase activity", "5s rrna binding", "7s rna binding", "7sk snrna binding", "Abc type glutathione s conjugate transporter activity", "Abc type transporter activity", "Abc type xenobiotic transporter activity", "Acetyl coa c acetyltransferase activity", "Acetyl coa c acyltransferase activity", "Acetyl coa hydrolase activity", "Acetylcholine receptor binding", "Acetylgalactosaminyltransferase activity", "Acetylglucosaminyltransferase activity", "Acetyltransferase activity", "Acid amino acid ligase activity", "Acid phosphatase activity", "Acid thiol ligase activity", "Acidic amino acid transmembrane transporter activity", "Actin binding", "Actin filament binding", "Actin monomer binding", "Actinin binding", "Active ion transmembrane transporter activity", "Active transmembrane transporter activity", "Activin binding", "Acyl carnitine transmembrane transporter activity", "Acyl coa binding", "Acyl coa dehydrogenase activity", "Acyl coa oxidase activity", "Acylglycerol lipase activity", "Acylglycerol o acyltransferase activity", "Acyltransferase activity", "Acyltransferase acyl groups converted into alkyl on transfer", "Adenosine deaminase activity", "Adenyl nucleotide binding", "Adenyl nucleotide exchange factor activity", "Adenylate cyclase binding", "Adenylate kinase activity", "Adenylyltransferase activity", "Adp binding", "Adp ribose diphosphatase activity", "Adp transmembrane transporter activity", "Adrenergic receptor binding", "Alanine transmembrane transporter activity", "Alcohol binding", "Alcohol dehydrogenase activity zinc dependent", "Alcohol dehydrogenase nad p plus activity", "Alcohol dehydrogenase nadpplus activity", "Aldehyde dehydrogenase nad p plus activity", "Aldehyde lyase activity", "Alditol nadpplus 1 oxidoreductase activity", "Aldo keto reductase nadp activity", "Alkali metal ion binding", "Alpha actinin binding", "Alpha catenin binding", "Alpha glucosidase activity", "Alpha tubulin binding", "Amide binding", "Amide transmembrane transporter activity", "Amidine lyase activity", "Amino acid binding", "Amino acid cation symporter activity", "Amino acid proton symporter activity", "Amino acid transmembrane transporter activity", "Aminoacyl trna editing activity", "Aminoacylase activity", "Aminopeptidase activity", "Ammonium transmembrane transporter activity", "Amp activated protein kinase activity", "Amp binding", "Amyloid beta binding", "Anaphase promoting complex binding", "Androgen receptor binding", "Androstan 3 alpha 17 beta diol dehydrogenase activity", "Anion cation symporter activity", "Anion channel activity", "Anion sodium symporter activity", "Anion transmembrane transporter activity", "Ankyrin binding", "Annealing activity", "Antigen binding", "Antioxidant activity", "Antiporter activity", "Apolipoprotein a i binding", "Apolipoprotein binding", "Apolipoprotein receptor binding", "Arachidonate coa ligase activity", "Arginine binding", "Armadillo repeat domain binding", "Aromatic amino acid transmembrane transporter activity", "Arp2 3 complex binding", "Arrestin family protein binding", "Aryl hydrocarbon receptor binding", "Arylesterase activity", "Arylsulfatase activity", "Aspartic endopeptidase activity intramembrane cleaving", "Aspartic type endopeptidase inhibitor activity", "Aspartic type peptidase activity", "Atp dependent activity", "Atp dependent activity acting on dna", "Atp dependent activity acting on rna", "Atp dependent chromatin remodeler activity", "Atp dependent dna dna annealing activity", "Atp dependent peptidase activity", "Atp dependent protein binding", "Atp hydrolysis activity", "Atp transmembrane transporter activity", "Atpase activator activity", "Atpase binding", "Atpase coupled cation transmembrane transporter activity", "Atpase coupled inorganic anion transmembrane transporter activity", "Atpase coupled intramembrane lipid transporter activity", "Atpase coupled ion transmembrane transporter activity", "Atpase coupled lipid transmembrane transporter activity", "Atpase coupled transmembrane transporter activity", "Atpase inhibitor activity", "Atpase regulator activity", "Azole transmembrane transporter activity", "Basal transcription machinery binding", "Beta 1 3 galactosyltransferase activity", "Beta 2 adrenergic receptor binding", "Beta 2 microglobulin binding", "Beta catenin binding", "Beta galactosidase activity", "Beta n acetylhexosaminidase activity", "Beta tubulin binding", "Bh domain binding", "Bh3 domain binding", "Bhlh transcription factor binding", "Bile acid binding", "Bile acid transmembrane transporter activity", "Biotin binding", "Box h aca snorna binding", "Branched chain amino acid transmembrane transporter activity", "Bubble dna binding", "C acetyltransferase activity", "C acyltransferase activity", "C methyltransferase activity", "C palmitoyltransferase activity", "C x c chemokine binding", "C x3 c chemokine binding", "C2h2 zinc finger domain binding", "C3hc4 type ring finger domain binding", "C4 dicarboxylate transmembrane transporter activity", "Cadherin binding", "Cadherin binding involved in cell cell adhesion", "Calcium cation antiporter activity", "Calcium channel inhibitor activity", "Calcium channel regulator activity", "Calcium dependent cysteine type endopeptidase activity", "Calcium dependent phospholipid binding", "Calcium dependent protein binding", "Calcium dependent protein kinase activity", "Calcium dependent protein serine threonine phosphatase activity", "Calcium independent phospholipase a2 activity", "Calcium ion binding", "Calcium ion transmembrane transporter activity", "Calmodulin binding", "Calmodulin dependent protein phosphatase activity", "Camp binding", "Camp dependent protein kinase activity", "Camp dependent protein kinase inhibitor activity", "Camp dependent protein kinase regulator activity", "Carbohydrate binding", "Carbohydrate derivative transmembrane transporter activity", "Carbohydrate kinase activity", "Carbon carbon lyase activity", "Carbon nitrogen ligase activity with glutamine as amido n donor", "Carbon nitrogen lyase activity", "Carbon oxygen lyase activity", "Carbon sulfur lyase activity", "Carbonyl reductase nadph activity", "Carboxy lyase activity", "Carboxylic acid binding", "Carboxylic ester hydrolase activity", "Carboxypeptidase activity", "Card domain binding", "Cardiolipin binding", "Cargo adaptor activity", "Cargo receptor activity", "Carnitine o acyltransferase activity", "Catalytic activity acting on a glycoprotein", "Catalytic activity acting on a nucleic acid", "Catalytic activity acting on a rrna", "Catalytic activity acting on a trna", "Catalytic activity acting on dna", "Catalytic activity acting on rna", "Cation cation antiporter activity", "Cation channel activity", "Cation chloride symporter activity", "Cation transmembrane transporter activity", "Ccr chemokine receptor binding", "Ccr3 chemokine receptor binding", "Ccr5 chemokine receptor binding", "Cdp alcohol phosphatidyltransferase activity", "Cell adhesion mediator activity", "Cell adhesion molecule binding", "Cell adhesive protein binding involved in bundle of his cell purkinje myocyte communication", "Cell cell adhesion mediator activity", "Cell matrix adhesion mediator activity", "Centromeric dna binding", "Ceramide 1 phosphate binding", "Ceramide 1 phosphate transfer activity", "Ceramide binding", "Cgmp binding", "Channel activator activity", "Channel inhibitor activity", "Channel regulator activity", "Chaperone binding", "Chemoattractant activity", "Chemokine binding", "Chemokine receptor binding", "Chitin binding", "Chloride channel inhibitor activity", "Chloride channel regulator activity", "Chloride ion binding", "Chloride transmembrane transporter activity", "Cholesterol binding", "Chondroitin sulfate binding", "Chromatin binding", "Chromatin dna binding", "Chromo shadow domain binding", "Cis regulatory region sequence specific dna binding", "Cis trans isomerase activity", "Class i dna apurinic or apyrimidinic site endonuclease activity", "Clathrin binding", "Clathrin heavy chain binding", "Clathrin light chain binding", "Co smad binding", "Coa hydrolase activity", "Coa transferase activity", "Cobalamin binding", "Collagen binding", "Collagen binding involved in cell matrix adhesion", "Complement binding", "Complement component c1q complex binding", "Complement component c3b binding", "Connexin binding", "Copper chaperone activity", "Copper ion binding", "Copper ion transmembrane transporter activity", "Core promoter sequence specific dna binding", "Coreceptor activity", "Coreceptor activity involved in wnt signaling pathway", "Coreceptor activity involved in wnt signaling pathway planar cell polarity pathway", "Cullin family protein binding", "Cuprous ion binding", "Cxcr chemokine receptor binding", "Cyclic nucleotide binding", "Cyclic nucleotide dependent protein kinase activity", "Cyclic nucleotide phosphodiesterase activity", "Cyclin binding", "Cyclin dependent protein kinase activity", "Cyclin dependent protein serine threonine kinase activator activity", "Cyclin dependent protein serine threonine kinase inhibitor activity", "Cyclin dependent protein serine threonine kinase regulator activity", "Cyclohydrolase activity", "Cyclosporin a binding", "Cysteine type endopeptidase activity", "Cysteine type endopeptidase activity involved in apoptotic process", "Cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Cysteine type endopeptidase inhibitor activity", "Cysteine type endopeptidase inhibitor activity involved in apoptotic process", "Cysteine type endopeptidase regulator activity involved in apoptotic process", "Cysteine type exopeptidase activity", "Cysteine type peptidase activity", "Cytidylyltransferase activity", "Cytochrome b5 reductase activity acting on nad p h", "Cytokine activity", "Cytokine binding", "Cytokine receptor binding", "Cytoskeletal anchor activity", "Cytoskeletal motor activity", "Cytoskeletal protein binding", "Cytoskeleton nuclear membrane anchor activity", "D loop dna binding", "D threo aldose 1 dehydrogenase activity", "D1 dopamine receptor binding", "Damaged dna binding", "Deacetylase activity", "Deaminase activity", "Death domain binding", "Death receptor activity", "Death receptor binding", "Demethylase activity", "Deoxynucleoside kinase activity", "Deoxyribonuclease activity", "Deoxyribonuclease i activity", "Diacylglycerol binding", "Diacylglycerol kinase activity", "Dicarboxylic acid transmembrane transporter activity", "Dihydropyrimidinase activity", "Dioxygenase activity", "Dipeptidase activity", "Dipeptidyl peptidase activity", "Diphosphotransferase activity", "Disordered domain specific binding", "Disulfide oxidoreductase activity", "Dna apurinic or apyrimidinic site endonuclease activity", "Dna binding bending", "Dna binding transcription activator activity", "Dna binding transcription factor activity", "Dna binding transcription factor binding", "Dna binding transcription repressor activity", "Dna clamp loader activity", "Dna directed dna polymerase activity", "Dna dna annealing activity", "Dna helicase activity", "Dna insertion or deletion binding", "Dna methyltransferase activity", "Dna n glycosylase activity", "Dna polymerase activity", "Dna polymerase binding", "Dna replication origin binding", "Dna secondary structure binding", "Dna topoisomerase activity", "Dna translocase activity", "Dolichyl diphosphooligosaccharide protein glycotransferase activity", "Dolichyl phosphate mannose protein mannosyltransferase activity", "Dopamine receptor binding", "Double stranded methylated dna binding", "Double stranded rna adenosine deaminase activity", "Double stranded rna binding", "Double stranded telomeric dna binding", "Dttp diphosphatase activity", "Dynactin binding", "Dynein complex binding", "Dynein heavy chain binding", "Dynein intermediate chain binding", "Dynein light chain binding", "Dynein light intermediate chain binding", "Dystroglycan binding", "E box binding", "Efflux transmembrane transporter activity", "Electron transfer activity", "Endodeoxyribonuclease activity", "Endodeoxyribonuclease activity producing 5 phosphomonoesters", "Endonuclease activity", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 3 phosphomonoesters", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Endopeptidase activator activity", "Endopeptidase activity", "Endopeptidase regulator activity", "Endoribonuclease activity", "Endoribonuclease activity producing 3 phosphomonoesters", "Endoribonuclease activity producing 5 phosphomonoesters", "Enoyl coa hydratase activity", "Enzyme activator activity", "Enzyme inhibitor activity", "Enzyme regulator activity", "Ephrin receptor binding", "Epidermal growth factor receptor binding", "Epoxide hydrolase activity", "Er retention sequence binding", "Estradiol 17 beta dehydrogenase activity", "Estrogen receptor binding", "Ether hydrolase activity", "Eukaryotic initiation factor 4e binding", "Exodeoxyribonuclease activity", "Exogenous protein binding", "Exonuclease activity", "Exonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Exopeptidase activity", "Exoribonuclease activity", "Exoribonuclease activity producing 5 phosphomonoesters", "Extracellular matrix binding", "Fad binding", "Fatty acid binding", "Fatty acid derivative binding", "Fatty acid ligase activity", "Fatty acid synthase activity", "Fatty acid transmembrane transporter activity", "Fatz binding", "Ferric iron binding", "Ferrous iron binding", "Fibroblast growth factor binding", "Fibroblast growth factor receptor binding", "Fibronectin binding", "Filamin binding", "Fk506 binding", "Flap endonuclease activity", "Flavin adenine dinucleotide binding", "Flippase activity", "Floppase activity", "Fmn binding", "Folic acid binding", "Folic acid transmembrane transporter activity", "Four way junction dna binding", "Four way junction helicase activity", "Frizzled binding", "Fructose 6 phosphate binding", "Fructose binding", "Fucosyltransferase activity", "G protein activity", "G protein alpha subunit binding", "G protein beta gamma subunit complex binding", "G protein beta subunit binding", "G protein coupled glutamate receptor binding", "G protein coupled opioid receptor activity", "G protein coupled receptor activity", "G protein coupled receptor binding", "G protein coupled serotonin receptor binding", "G quadruplex dna binding", "G quadruplex rna binding", "G rich strand telomeric dna binding", "Gaba receptor binding", "Galactosidase activity", "Galactoside binding", "Galactosyltransferase activity", "Gamma aminobutyric acid transmembrane transporter activity", "Gamma catenin binding", "Gamma tubulin binding", "Ganglioside binding", "Gated channel activity", "Gdp binding", "Gdp dissociation inhibitor activity", "General transcription initiation factor activity", "General transcription initiation factor binding", "Glucocorticoid receptor binding", "Glucose binding", "Glucosidase activity", "Glucosyltransferase activity", "Glucuronosyltransferase activity", "Glutamate receptor binding", "Glutathione disulfide oxidoreductase activity", "Glutathione oxidoreductase activity", "Glutathione peroxidase activity", "Glutathione transferase activity", "Glutathione transmembrane transporter activity", "Glyceraldehyde 3 phosphate dehydrogenase nadplus non phosphorylating activity", "Glycerophospholipid flippase activity", "Glycine binding", "Glycolipid binding", "Glycolipid mannosyltransferase activity", "Glycosaminoglycan binding", "Glycosphingolipid binding", "Glycosyltransferase activity", "Gpi anchor binding", "Growth factor activity", "Growth factor binding", "Growth factor receptor binding", "Gtp dependent protein binding", "Gtpase activating protein binding", "Gtpase activator activity", "Gtpase activity", "Gtpase binding", "Gtpase inhibitor activity", "Guanyl nucleotide binding", "Guanyl nucleotide exchange factor activity", "Guanylate kinase activity", "Guanylyltransferase activity", "H4 histone acetyltransferase activity", "Heat shock protein binding", "Helicase activity", "Heme transmembrane transporter activity", "Heparin binding", "Hexokinase activity", "Hexosaminidase activity", "Hexosyltransferase activity", "High density lipoprotein particle binding", "Histone acetyltransferase binding", "Histone arginine n methyltransferase activity", "Histone binding", "Histone deacetylase activity h3 k14 specific", "Histone deacetylase binding", "Histone deacetylase regulator activity", "Histone h3 di monomethyl lysine 9 demethylase activity", "Histone h3 methyl lysine 4 demethylase activity", "Histone h3 methyl lysine 9 demethylase activity", "Histone kinase activity", "Histone lysine n methyltransferase activity", "Histone methyltransferase activity", "Histone methyltransferase activity h3 k36 specific", "Histone methyltransferase activity h3 k4 specific", "Histone methyltransferase activity h3 k9 specific", "Histone methyltransferase activity h4 k20 specific", "Histone methyltransferase binding", "Histone serine kinase activity", "Histone threonine kinase activity", "Hormone activity", "Hormone binding", "Hormone receptor binding", "Hsp70 protein binding", "Hsp90 protein binding", "Hyaluronic acid binding", "Hyalurononglucosaminidase activity", "Hydro lyase activity", "Hydrolase activity acting on acid anhydrides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amidines", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amides", "Hydrolase activity acting on ester bonds", "Hydrolase activity acting on ether bonds", "Hydrolase activity acting on glycosyl bonds", "Hydrolase activity hydrolyzing n glycosyl compounds", "Hydrolase activity hydrolyzing o glycosyl compounds", "Hydroxymethyl formyl and related transferase activity", "I smad binding", "Identical protein binding", "Ige binding", "Immunoglobulin binding", "Immunoglobulin receptor binding", "Importin alpha family protein binding", "Inorganic anion transmembrane transporter activity", "Inorganic diphosphatase activity", "Inorganic molecular entity transmembrane transporter activity", "Inorganic phosphate transmembrane transporter activity", "Inositol 1 4 5 trisphosphate 5 phosphatase activity", "Inositol phosphate phosphatase activity", "Inositol polyphosphate 5 phosphatase activity", "Inositol tetrakisphosphate phosphatase activity", "Inositol trisphosphate kinase activity", "Inositol trisphosphate phosphatase activity", "Insulin binding", "Insulin like growth factor binding", "Insulin like growth factor i binding", "Insulin like growth factor ii binding", "Insulin like growth factor receptor binding", "Insulin receptor binding", "Insulin receptor substrate binding", "Integrin binding", "Interleukin 1 receptor binding", "Interleukin 2 receptor binding", "Interleukin 6 receptor binding", "Intermediate filament binding", "Intracellular calcium activated chloride channel activity", "Intraciliary transport particle b binding", "Intramembrane lipid transporter activity", "Intramolecular oxidoreductase activity", "Intramolecular oxidoreductase activity interconverting aldoses and ketoses", "Intramolecular oxidoreductase activity transposing c c bonds", "Intramolecular transferase activity", "Intramolecular transferase activity phosphotransferases", "Intronic transcription regulatory region sequence specific dna binding", "Ion gated channel activity", "Ion transmembrane transporter activity", "Ionotropic glutamate receptor binding", "Iron ion binding", "Iron ion transmembrane transporter activity", "Isocitrate dehydrogenase activity", "Isomerase activity", "Isopeptidase activity", "Isoprenoid binding", "Jun kinase binding", "K48 linked polyubiquitin modification dependent protein binding", "K63 linked polyubiquitin modification dependent protein binding", "Keratin filament binding", "Kinase activator activity", "Kinase activity", "Kinase binding", "Kinase inhibitor activity", "Kinase regulator activity", "Kinesin binding", "Kinetochore binding", "L alanine transmembrane transporter activity", "L amino acid transmembrane transporter activity", "L ascorbic acid binding", "L aspartate transmembrane transporter activity", "L glutamine transmembrane transporter activity", "L lactate dehydrogenase activity", "L leucine transmembrane transporter activity", "L ornithine transmembrane transporter activity", "L serine transmembrane transporter activity", "Lactate dehydrogenase activity", "Lactate transmembrane transporter activity", "Lamin binding", "Laminin binding", "Large ribosomal subunit rrna binding", "Leucine binding", "Leucine zipper domain binding", "Leukotriene c4 synthase activity", "Ligand gated ion channel activity", "Ligase activity", "Ligase activity forming carbon carbon bonds", "Ligase activity forming carbon nitrogen bonds", "Ligase activity forming carbon oxygen bonds", "Ligase activity forming carbon sulfur bonds", "Ligase activity forming phosphoric ester bonds", "Lim domain binding", "Lipase activator activity", "Lipase activity", "Lipase binding", "Lipase inhibitor activity", "Lipid binding", "Lipid kinase activity", "Lipid phosphatase activity", "Lipid transfer activity", "Lipid transporter activity", "Lipopolysaccharide binding", "Lipopolysaccharide immune receptor activity", "Lipoprotein particle receptor activity", "Lipoprotein particle receptor binding", "Long chain acyl coa dehydrogenase activity", "Long chain fatty acid binding", "Long chain fatty acid coa ligase activity", "Long chain fatty acid transporter activity", "Long chain fatty acyl coa binding", "Low density lipoprotein particle binding", "Low density lipoprotein particle receptor binding", "Lrr domain binding", "Lyase activity", "Lys48 specific deubiquitinase activity", "Lys63 specific deubiquitinase activity", "Lysine acetylated histone binding", "Lysine n methyltransferase activity", "Lysophosphatidic acid binding", "Lysophosphatidic acid phosphatase activity", "Lysophospholipase activity", "Lysophospholipid acyltransferase activity", "M7g 5 pppn diphosphatase activity", "Macrolide binding", "Macromolecule transmembrane transporter activity", "Magnesium ion binding", "Magnesium ion transmembrane transporter activity", "Malate dehydrogenase activity", "Manganese ion binding", "Manganese ion transmembrane transporter activity", "Mannose binding", "Mannosyltransferase activity", "Map kinase activity", "Map kinase kinase activity", "Map kinase kinase kinase activity", "Map kinase kinase kinase kinase activity", "Map kinase phosphatase activity", "Map kinase scaffold activity", "Map kinase tyrosine serine threonine phosphatase activity", "Mdm2 mdm4 family protein binding", "Medium chain fatty acid coa ligase activity", "Membrane insertase activity", "Metal cluster binding", "Metal dependent deubiquitinase activity", "Metal ion proton antiporter activity", "Metal ion transmembrane transporter activity", "Metalloaminopeptidase activity", "Metallocarboxypeptidase activity", "Metallochaperone activity", "Metallodipeptidase activity", "Metalloendopeptidase activity", "Metalloexopeptidase activity", "Metallopeptidase activity", "Methyl cpg binding", "Methylated histone binding", "Mhc class i protein binding", "Mhc class ib protein binding", "Mhc class ii protein binding", "Mhc class ii protein complex binding", "Mhc protein binding", "Mhc protein complex binding", "Microfilament motor activity", "Microtubule binding", "Microtubule minus end binding", "Microtubule motor activity", "Microtubule plus end binding", "Minor groove of adenine thymine rich dna binding", "Minus end directed microtubule motor activity", "Mirna binding", "Misfolded protein binding", "Mismatch repair complex binding", "Mismatched dna binding", "Mitochondrial ribosome binding", "Mitochondrion targeting sequence binding", "Mitogen activated protein kinase binding", "Mitogen activated protein kinase kinase binding", "Mitogen activated protein kinase kinase kinase binding", "Mitogen activated protein kinase p38 binding", "Modification dependent protein binding", "Modified amino acid binding", "Modified amino acid transmembrane transporter activity", "Molecular adaptor activity", "Molecular carrier activity", "Molecular function activator activity", "Molecular function inhibitor activity", "Molecular function regulator", "Molecular sequestering activity", "Molecular transducer activity", "Molybdopterin cofactor binding", "Monocarboxylic acid binding", "Monocarboxylic acid transmembrane transporter activity", "Monooxygenase activity", "Monosaccharide binding", "Mrf binding", "Mrna 3 utr au rich region binding", "Mrna 3 utr binding", "Mrna 5 utr binding", "Mrna binding", "Mrna methyltransferase activity", "Muscle alpha actinin binding", "Mutlalpha complex binding", "Myosin binding", "Myosin ii binding", "Myosin v binding", "Myristoyltransferase activity", "N acetylgalactosamine 4 o sulfotransferase activity", "N acetyllactosaminide beta 1 3 n acetylglucosaminyltransferase activity", "N acetyltransferase activity", "N acylsphingosine amidohydrolase activity", "N acyltransferase activity", "N methyltransferase activity", "N6 methyladenosine containing rna binding", "Nad binding", "Nad dependent protein deacetylase activity", "Nad p h oxidase h2o2 forming activity", "Nad retinol dehydrogenase activity", "Nadh dehydrogenase activity", "Nadh pyrophosphatase activity", "Nadp binding", "Nadp retinol dehydrogenase activity", "Nadph binding", "Nadplus adp ribosyltransferase activity", "Nadplus binding", "Nadplus kinase activity", "Nedd8 specific protease activity", "Nedd8 transferase activity", "Neurexin family protein binding", "Neuroligin family protein binding", "Neurotransmitter receptor regulator activity", "Neurotransmitter transmembrane transporter activity", "Neurotrophin binding", "Neurotrophin receptor binding", "Neurotrophin trk receptor binding", "Neutral amino acid transmembrane transporter activity", "Nf kappab binding", "Nf kappab inducing kinase activity", "Nfat protein binding", "Nitric oxide synthase binding", "Nitric oxide synthase regulator activity", "Nitrite reductase activity", "Non membrane spanning protein tyrosine kinase activity", "Non membrane spanning protein tyrosine phosphatase activity", "Notch binding", "Nuclear export signal receptor activity", "Nuclear import signal receptor activity", "Nuclear localization sequence binding", "Nuclear receptor activity", "Nuclear receptor binding", "Nuclear receptor coactivator activity", "Nuclease activity", "Nucleobase containing compound kinase activity", "Nucleobase containing compound transmembrane transporter activity", "Nucleobase transmembrane transporter activity", "Nucleocytoplasmic carrier activity", "Nucleoside binding", "Nucleoside diphosphatase activity", "Nucleoside diphosphate kinase activity", "Nucleoside kinase activity", "Nucleoside monophosphate kinase activity", "Nucleoside transmembrane transporter activity", "Nucleoside triphosphatase regulator activity", "Nucleoside triphosphate diphosphatase activity", "Nucleosomal dna binding", "Nucleosome binding", "Nucleotidase activity", "Nucleotide diphosphatase activity", "Nucleotide phosphatase activity acting on free nucleotides", "Nucleotide sugar transmembrane transporter activity", "Nucleotide transmembrane transporter activity", "Nucleotidyltransferase activity", "O acetyltransferase activity", "O acyltransferase activity", "O methyltransferase activity", "O palmitoyltransferase activity", "Oleate transmembrane transporter activity", "Oligopeptide binding", "Oligopeptide transmembrane transporter activity", "Oligosaccharide binding", "Oligosaccharyl transferase activity", "Omega peptidase activity", "Opsonin binding", "Organic acid binding", "Organic acid transmembrane transporter activity", "Organic anion transmembrane transporter activity", "Organic cation transmembrane transporter activity", "Organic hydroxy compound transmembrane transporter activity", "Organophosphate ester transmembrane transporter activity", "Oxidative phosphorylation uncoupler activity", "Oxidative rna demethylase activity", "Oxidized dna binding", "Oxidoreductase activity", "Oxidoreductase activity acting on a heme group of donors", "Oxidoreductase activity acting on a sulfur group of donors", "Oxidoreductase activity acting on a sulfur group of donors disulfide as acceptor", "Oxidoreductase activity acting on a sulfur group of donors nad p as acceptor", "Oxidoreductase activity acting on a sulfur group of donors oxygen as acceptor", "Oxidoreductase activity acting on ch oh group of donors", "Oxidoreductase activity acting on ch or ch2 groups", "Oxidoreductase activity acting on diphenols and related substances as donors", "Oxidoreductase activity acting on nad p h", "Oxidoreductase activity acting on nad p h heme protein as acceptor", "Oxidoreductase activity acting on nad p h oxygen as acceptor", "Oxidoreductase activity acting on nad p h quinone or similar compound as acceptor", "Oxidoreductase activity acting on other nitrogenous compounds as donors", "Oxidoreductase activity acting on other nitrogenous compounds as donors cytochrome as acceptor", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen nad p h as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced flavin or flavoprotein as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced pteridine as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water", "Oxidoreductase activity acting on peroxide as acceptor", "Oxidoreductase activity acting on single donors with incorporation of molecular oxygen", "Oxidoreductase activity acting on the aldehyde or oxo group of donors", "Oxidoreductase activity acting on the aldehyde or oxo group of donors disulfide as acceptor", "Oxidoreductase activity acting on the aldehyde or oxo group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors", "Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors oxygen as acceptor", "Oxidoreductase activity acting on the ch nh group of donors", "Oxidoreductase activity acting on the ch nh group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch nh2 group of donors", "Oxidoreductase activity acting on the ch nh2 group of donors oxygen as acceptor", "Oxidoreduction driven active transmembrane transporter activity", "Oxo acid lyase activity", "Oxygen binding", "Oxygen sensor activity", "Oxysterol binding", "P type calcium transporter activity", "P type potassium transmembrane transporter activity", "P type transmembrane transporter activity", "P53 binding", "Palmitoyl coa hydrolase activity", "Palmitoyl protein hydrolase activity", "Palmitoyltransferase activity", "Passive transmembrane transporter activity", "Patched binding", "Pattern recognition receptor activity", "Pdz domain binding", "Pentosyltransferase activity", "Peptidase activator activity", "Peptidase activator activity involved in apoptotic process", "Peptidase activity", "Peptidase regulator activity", "Peptide alpha n acetyltransferase activity", "Peptide antigen binding", "Peptide binding", "Peptide hormone binding", "Peptide hormone receptor binding", "Peptide lysine n acetyltransferase activity", "Peptide n acetyltransferase activity", "Peptide receptor activity", "Peptide transmembrane transporter activity", "Peptidoglycan binding", "Peptidyl proline 4 dioxygenase activity", "Peptidyl proline dioxygenase activity", "Peroxiredoxin activity", "Peroxisome proliferator activated receptor binding", "Peroxisome targeting sequence binding", "Phosphatase activator activity", "Phosphatase activity", "Phosphatase binding", "Phosphatase inhibitor activity", "Phosphatase regulator activity", "Phosphate ion binding", "Phosphatidic acid binding", "Phosphatidyl phospholipase b activity", "Phosphatidylcholine binding", "Phosphatidylcholine floppase activity", "Phosphatidylcholine transfer activity", "Phosphatidylcholine transporter activity", "Phosphatidylethanolamine binding", "Phosphatidylethanolamine flippase activity", "Phosphatidylglycerol binding", "Phosphatidylinositol 3 4 5 trisphosphate 3 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate 5 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate binding", "Phosphatidylinositol 3 4 bisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate 3 phosphatase activity", "Phosphatidylinositol 3 5 bisphosphate 5 phosphatase activity", "Phosphatidylinositol 3 5 bisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate phosphatase activity", "Phosphatidylinositol 3 kinase activity", "Phosphatidylinositol 3 kinase binding", "Phosphatidylinositol 3 kinase regulatory subunit binding", "Phosphatidylinositol 3 phosphate binding", "Phosphatidylinositol 4 5 bisphosphate 3 kinase activity", "Phosphatidylinositol 4 5 bisphosphate 5 phosphatase activity", "Phosphatidylinositol 4 5 bisphosphate binding", "Phosphatidylinositol 4 5 bisphosphate phosphatase activity", "Phosphatidylinositol 4 phosphate binding", "Phosphatidylinositol 5 phosphate binding", "Phosphatidylinositol binding", "Phosphatidylinositol bisphosphate binding", "Phosphatidylinositol bisphosphate kinase activity", "Phosphatidylinositol bisphosphate phosphatase activity", "Phosphatidylinositol kinase activity", "Phosphatidylinositol monophosphate phosphatase activity", "Phosphatidylinositol phosphate 4 phosphatase activity", "Phosphatidylinositol phosphate 5 phosphatase activity", "Phosphatidylinositol phosphate binding", "Phosphatidylinositol phosphate kinase activity", "Phosphatidylinositol phosphate phosphatase activity", "Phosphatidylinositol transfer activity", "Phosphatidylinositol trisphosphate phosphatase activity", "Phosphatidylserine 1 acylhydrolase activity", "Phosphatidylserine binding", "Phosphodiesterase i activity", "Phosphofructokinase activity", "Phospholipase a1 activity", "Phospholipase a2 activity", "Phospholipase a2 inhibitor activity", "Phospholipase activity", "Phospholipase binding", "Phospholipase c activity", "Phospholipase d activity", "Phospholipase inhibitor activity", "Phospholipid binding", "Phospholipid transfer activity", "Phospholipid transporter activity", "Phosphoprotein binding", "Phosphoprotein phosphatase activity", "Phosphoric diester hydrolase activity", "Phosphoric ester hydrolase activity", "Phosphorus oxygen lyase activity", "Phosphoserine residue binding", "Phosphotransferase activity for other substituted phosphate groups", "Phosphotransferase activity nitrogenous group as acceptor", "Phosphotransferase activity phosphate group as acceptor", "Phosphotyrosine residue binding", "Plus end directed microtubule motor activity", "Poly a binding", "Poly a specific ribonuclease activity", "Poly g binding", "Poly purine tract binding", "Poly pyrimidine tract binding", "Polynucleotide adenylyltransferase activity", "Polypeptide n acetylgalactosaminyltransferase activity", "Polysaccharide binding", "Polysome binding", "Polyubiquitin modification dependent protein binding", "Porin activity", "Potassium channel inhibitor activity", "Potassium channel regulator activity", "Potassium chloride symporter activity", "Potassium ion binding", "Potassium ion transmembrane transporter activity", "Pre mirna binding", "Pre mrna 3 splice site binding", "Pre mrna binding", "Pre mrna intronic binding", "Prenyltransferase activity", "Primary active transmembrane transporter activity", "Primary mirna binding", "Procollagen proline 4 dioxygenase activity", "Procollagen proline dioxygenase activity", "Profilin binding", "Proline rich region binding", "Promoter specific chromatin binding", "Protease binding", "Proteasome activating activity", "Proteasome binding", "Protein adp ribosylase activity", "Protein antigen binding", "Protein arginine n methyltransferase activity", "Protein arginine omega n asymmetric methyltransferase activity", "Protein arginine omega n monomethyltransferase activity", "Protein binding involved in heterotypic cell cell adhesion", "Protein c terminus binding", "Protein carboxyl o methyltransferase activity", "Protein carrier chaperone", "Protein containing complex binding", "Protein deacetylase activity", "Protein demethylase activity", "Protein dimerization activity", "Protein disaggregase activity", "Protein disulfide isomerase activity", "Protein disulfide reductase nad p activity", "Protein domain specific binding", "Protein folding chaperone", "Protein geranylgeranyltransferase activity", "Protein heterodimerization activity", "Protein homodimerization activity", "Protein hormone receptor activity", "Protein kinase a binding", "Protein kinase a catalytic subunit binding", "Protein kinase a regulatory subunit binding", "Protein kinase activity", "Protein kinase b binding", "Protein kinase c activity", "Protein kinase c binding", "Protein lipid complex binding", "Protein macromolecule adaptor activity", "Protein membrane adaptor activity", "Protein methyltransferase activity", "Protein n terminus binding", "Protein phosphatase 1 binding", "Protein phosphatase 2a binding", "Protein phosphatase activator activity", "Protein phosphatase binding", "Protein phosphatase regulator activity", "Protein phosphorylated amino acid binding", "Protein prenyltransferase activity", "Protein self association", "Protein sequestering activity", "Protein serine kinase activity", "Protein serine threonine kinase activator activity", "Protein serine threonine kinase activity", "Protein serine threonine kinase inhibitor activity", "Protein serine threonine phosphatase activity", "Protein serine threonine tyrosine kinase activity", "Protein transmembrane transporter activity", "Protein transporter activity", "Protein tyrosine kinase activator activity", "Protein tyrosine kinase activity", "Protein tyrosine kinase binding", "Protein tyrosine kinase inhibitor activity", "Protein tyrosine phosphatase activity", "Protein tyrosine serine threonine phosphatase activity", "Protein tyrosine threonine phosphatase activity", "Proteoglycan binding", "Proton channel activity", "Proton transmembrane transporter activity", "Proton transporting atp synthase activity rotational mechanism", "Pseudouridine synthase activity", "Purine nucleotide transmembrane transporter activity", "Pyrimidine nucleoside transmembrane transporter activity", "Pyrimidine nucleotide binding", "Pyrimidine nucleotide sugar transmembrane transporter activity", "Pyrophosphate hydrolysis driven proton transmembrane transporter activity", "Pyruvate dehydrogenase acetyl transferring kinase activity", "Pyruvate dehydrogenase activity", "Quaternary ammonium group binding", "Quaternary ammonium group transmembrane transporter activity", "Quinone binding", "R smad binding", "Racemase and epimerase activity", "Racemase and epimerase activity acting on carbohydrates and derivatives", "Rage receptor binding", "Rdna binding", "Receptor antagonist activity", "Receptor tyrosine kinase binding", "Regulatory rna binding", "Retinal binding", "Retinal dehydrogenase activity", "Retinoic acid binding", "Retinoic acid receptor binding", "Retinoid x receptor binding", "Retinol binding", "Retromer complex binding", "Ribonuclease activity", "Ribonuclease p activity", "Ribonuclease p rna binding", "Ribonucleoprotein complex binding", "Ribonucleotide binding", "Ribose phosphate diphosphokinase activity", "Ribosomal large subunit binding", "Ribosomal protein s6 kinase activity", "Ribosomal small subunit binding", "Ribosome binding", "Rna 2 o methyltransferase activity", "Rna 7 methylguanosine cap binding", "Rna adenylyltransferase activity", "Rna binding", "Rna binding involved in posttranscriptional gene silencing", "Rna cap binding", "Rna directed dna polymerase activity", "Rna dna hybrid ribonuclease activity", "Rna methyltransferase activity", "Rna polymerase activity", "Rna polymerase binding", "Rna polymerase core enzyme binding", "Rna polymerase i general transcription initiation factor activity", "Rna polymerase i transcription regulatory region sequence specific dna binding", "Rna polymerase ii activity", "Rna polymerase ii c terminal domain binding", "Rna polymerase ii core promoter sequence specific dna binding", "Rna polymerase ii ctd heptapeptide repeat kinase activity", "Rna polymerase ii general transcription initiation factor activity", "Rna polymerase ii general transcription initiation factor binding", "Rna polymerase ii intronic transcription regulatory region sequence specific dna binding", "Rna polymerase ii specific dna binding transcription factor binding", "Rna polymerase iii transcription regulatory region sequence specific dna binding", "Rna stem loop binding", "Rna strand annealing activity", "Rrna binding", "Rrna cytosine methyltransferase activity", "S acyltransferase activity", "S adenosyl l methionine binding", "S adenosylmethionine dependent methyltransferase activity", "S methyltransferase activity", "S100 protein binding", "Salt transmembrane transporter activity", "Scaffold protein binding", "Scavenger receptor activity", "Secondary active transmembrane transporter activity", "Semaphorin receptor activity", "Sequence specific dna binding", "Sequence specific mrna binding", "Sequence specific single stranded dna binding", "Serine hydrolase activity", "Serine transmembrane transporter activity", "Serine type carboxypeptidase activity", "Serine type endopeptidase inhibitor activity", "Serine type exopeptidase activity", "Sh2 domain binding", "Sh3 domain binding", "Signal recognition particle binding", "Signal sequence binding", "Signaling adaptor activity", "Signaling receptor binding", "Signaling receptor complex adaptor activity", "Signaling receptor inhibitor activity", "Signaling receptor regulator activity", "Single stranded dna 3 5 exodeoxyribonuclease activity", "Single stranded dna binding", "Single stranded dna endodeoxyribonuclease activity", "Single stranded dna exodeoxyribonuclease activity", "Single stranded dna helicase activity", "Single stranded rna binding", "Single stranded telomeric dna binding", "Sirna binding", "Smad binding", "Small molecule sensor activity", "Small protein activating enzyme binding", "Small ribosomal subunit rrna binding", "Snap receptor activity", "Snare binding", "Snorna binding", "Snrna binding", "Snrnp binding", "Sodium channel inhibitor activity", "Sodium channel regulator activity", "Sodium chloride symporter activity", "Sodium ion binding", "Sodium ion transmembrane transporter activity", "Solute anion antiporter activity", "Solute cation antiporter activity", "Solute cation symporter activity", "Solute proton antiporter activity", "Solute proton symporter activity", "Solute sodium symporter activity", "Spectrin binding", "Sphingolipid binding", "Sphingolipid transfer activity", "Sphingolipid transporter activity", "Sphingomyelin phosphodiesterase activity", "Sphingosine n acyltransferase activity", "Steroid binding", "Steroid dehydrogenase activity", "Steroid dehydrogenase activity acting on the ch oh group of donors nad or nadp as acceptor", "Steroid hormone binding", "Steroid hormone receptor activity", "Sterol binding", "Sterol esterase activity", "Sterol transfer activity", "Sterol transporter activity", "Store operated calcium channel activity", "Structural constituent of cytoskeleton", "Structural constituent of eye lens", "Structural constituent of muscle", "Structural constituent of nuclear pore", "Structural constituent of postsynapse", "Structural constituent of postsynaptic actin cytoskeleton", "Structural constituent of presynaptic active zone", "Structural constituent of ribosome", "Structural constituent of synapse", "Structural molecule activity", "Structural molecule activity conferring elasticity", "Succinate transmembrane transporter activity", "Sulfate binding", "Sulfate transmembrane transporter activity", "Sulfatide binding", "Sulfotransferase activity", "Sulfur compound binding", "Sulfur compound transmembrane transporter activity", "Sulfuric ester hydrolase activity", "Sulfurtransferase activity", "Sumo binding", "Sumo ligase activity", "Sumo specific protease activity", "Sumo transferase activity", "Supercoiled dna binding", "Superoxide dismutase activity", "Symporter activity", "Syndecan binding", "Syntaxin 1 binding", "Syntaxin binding", "T cell receptor binding", "Tap binding", "Tat protein binding", "Tau protein binding", "Tau protein kinase activity", "Tbp class protein binding", "Telomerase activity", "Telomerase inhibitor activity", "Telomerase rna binding", "Telomeric dna binding", "Testosterone dehydrogenase nad p activity", "Testosterone dehydrogenase nadplus activity", "Tetrapyrrole binding", "Tfiib class transcription factor binding", "Tfiid class transcription factor complex binding", "Thiamine pyrophosphate binding", "Thioesterase binding", "Thiol oxidase activity", "Thiolester hydrolase activity", "Thioredoxin disulfide reductase activity", "Threonine type endopeptidase activity", "Threonine type peptidase activity", "Thyroid hormone receptor binding", "Titin binding", "Toxic substance binding", "Tpr domain binding", "Transcription coactivator activity", "Transcription coactivator binding", "Transcription coregulator activity", "Transcription coregulator binding", "Transcription corepressor activity", "Transcription corepressor binding", "Transcription elongation regulator activity", "Transcription factor binding", "Transcription regulator activity", "Transcription regulator inhibitor activity", "Transferase activity transferring alkyl or aryl other than methyl groups", "Transferase activity transferring nitrogenous groups", "Transferase activity transferring one carbon groups", "Transferase activity transferring phosphorus containing groups", "Transferase activity transferring sulphur containing groups", "Transferrin receptor binding", "Transforming growth factor beta receptor binding", "Transition metal ion binding", "Transition metal ion transmembrane transporter activity", "Transketolase or transaldolase activity", "Translation activator activity", "Translation elongation factor activity", "Translation factor activity rna binding", "Translation initiation factor activity", "Translation initiation factor binding", "Translation regulator activity", "Translation regulator activity nucleic acid binding", "Translation repressor activity", "Translation repressor activity mrna regulatory element binding", "Translation termination factor activity", "Transmembrane receptor protein kinase activity", "Transmembrane receptor protein tyrosine kinase activity", "Transmembrane transporter binding", "Transporter activity", "Tripeptide transmembrane transporter activity", "Trna binding", "Trna cytosine methyltransferase activity", "Trna guanine methyltransferase activity", "Trna methyltransferase activity", "Trna specific adenosine deaminase activity", "Trna specific ribonuclease activity", "Tropomyosin binding", "Tubulin binding", "Tumor necrosis factor activated receptor activity", "Tumor necrosis factor receptor binding", "Tumor necrosis factor receptor superfamily binding", "Type 1 fibroblast growth factor receptor binding", "Type i transforming growth factor beta receptor binding", "U1 snrna binding", "U2 snrna binding", "U3 snorna binding", "U4 snrna binding", "U6 snrna binding", "Ubiquinol cytochrome c reductase activity", "Ubiquinone binding", "Ubiquitin binding", "Ubiquitin conjugating enzyme binding", "Ubiquitin ligase substrate adaptor activity", "Ubiquitin like modifier activating enzyme activity", "Ubiquitin like protein binding", "Ubiquitin like protein conjugating enzyme activity", "Ubiquitin like protein conjugating enzyme binding", "Ubiquitin like protein ligase activity", "Ubiquitin like protein ligase binding", "Ubiquitin like protein specific isopeptidase activity", "Ubiquitin like protein specific protease activity", "Ubiquitin like protein transferase activity", "Ubiquitin protein transferase activator activity", "Ubiquitin protein transferase inhibitor activity", "Ubiquitin protein transferase regulator activity", "Ubiquitin specific protease binding", "Ubiquitin ubiquitin ligase activity", "Ubiquitination like modification dependent protein binding", "Udp galactose beta n acetylglucosamine beta 1 3 galactosyltransferase activity", "Udp glucosyltransferase activity", "Udp glycosyltransferase activity", "Udp xylosyltransferase activity", "Unfolded protein binding", "Unmethylated cpg binding", "Uridine transmembrane transporter activity", "Uridylyltransferase activity", "Vascular endothelial growth factor receptor 2 binding", "Vascular endothelial growth factor receptor binding", "Very long chain fatty acid coa ligase activity", "Vinculin binding", "Virion binding", "Vitamin b6 binding", "Vitamin binding", "Vitamin d binding", "Vitamin d receptor binding", "Vitamin transmembrane transporter activity", "Voltage gated anion channel activity", "Voltage gated channel activity", "Voltage gated chloride channel activity", "Volume sensitive anion channel activity", "Water channel activity", "Water transmembrane transporter activity", "Wd40 repeat domain binding", "Wide pore channel activity", "Ww domain binding", "Xenobiotic transmembrane transporter activity", "Zinc ion binding", "Zinc ion transmembrane transporter activity"], "available_proteins": ["AAMP", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAP2", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADH5", "ADI1", "ADK", "ADNP", "ADO", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP17A", "AKAP8", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALKBH5", "ALYREF", "AMOT", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP3B1", "AP3M1", "APEH", "APEX1", "API5", "APMAP", "APOL2", "APRT", "AQR", "ARCN1", "ARF4", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL6IP4", "ARL8B", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "AS3MT", "ASAH1", "ASCC2", "ASCC3", "ASNA1", "ASNS", "ASPH", "ASPM", "ASRGL1", "ATAD1", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATG4B", "ATIC", "ATL2", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7B", "ATPIF1", "ATRX", "ATXN2L", "AUP1", "B4GAT1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAK1", "BANF1", "BAP18", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BCAP31", "BCAT2", "BCCIP", "BCL10", "BCL2L13", "BCLAF1", "BCS1L", "BET1", "BIRC6", "BLMH", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOP1", "BPNT1", "BRD2", "BRIX1", "BSG", "BTF3", "BUB3", "BUD31", "BYSL", "BZW1", "BZW2", "C1QBP", "C1orf123", "C1orf35", "C20orf27", "C2CD5", "CAB39", "CACUL1", "CACYBP", "CAD", "CALD1", "CALR", "CALU", "CAND1", "CANX", "CAP1", "CAPN1", "CAPRIN1", "CAPZA1", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP2", "CASP3", "CASP6", "CAST", "CBFB", "CBR1", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC124", "CCDC47", "CCDC6", "CCDC86", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD276", "CD2AP", "CD2BP2", "CD47", "CD81", "CDC23", "CDC27", "CDC37", "CDC42", "CDC45", "CDC5L", "CDC73", "CDK1", "CDK13", "CDK2", "CDK4", "CDK5RAP3", "CDK6", "CDKAL1", "CDKN2A", "CDKN2AIP", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPV", "CEP44", "CEP55", "CERS2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP2A", "CHMP5", "CHORDC1", "CHRAC1", "CHST14", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CIZ1", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP2", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLP1", "CLPB", "CLPP", "CLPX", "CLSPN", "CLTA", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNOT1", "CNOT7", "CNOT9", "CNP", "COASY", "COIL", "COL4A3BP", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS4", "COPS5", "COPS6", "CORO1C", "COTL1", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "CPD", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZL1", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWC22", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DCAF13", "DCAF7", "DCAKD", "DCD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCXR", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHFR", "DHPS", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX40", "DHX8", "DHX9", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIP2B", "DIS3", "DIS3L2", "DKC1", "DLAT", "DLD", "DLST", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOHH", "DPF2", "DPH2", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DRG1", "DRG2", "DSG2", "DSP", "DST", "DSTN", "DTL", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC3", "EDF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFL1", "EFTUD2", "EHD1", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENDOD1", "ENO1", "ENOPH1", "ENSA", "ENY2", "EPB41", "EPB41L2", "EPB41L3", "EPHX1", "EPHX2", "EPPK1", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERC1", "ERCC2", "ERCC6L", "ERGIC3", "ERH", "ERI1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC4", "EXOC5", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EYA3", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAHD1", "FAHD2A", "FAM120A", "FAM208A", "FAM3C", "FAM49B", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FAU", "FBL", "FBXO22", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FLCN", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FMR1", "FN3KRP", "FNDC3A", "FNTA", "FNTB", "FOXC1", "FOXRED1", "FRG1", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCLM", "GCN1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GIGYF2", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLTP", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GNS", "GOLGA3", "GOLGB1", "GOPC", "GOT1", "GOT2", "GPAA1", "GPATCH4", "GPD2", "GPI", "GPKOW", "GPR107", "GPS1", "GPT2", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2E1", "GTF2I", "GTPBP1", "GTPBP10", "GTPBP4", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS4", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDGFL2", "HDHD2", "HDLBP", "HEATR1", "HEATR3", "HEBP1", "HECTD1", "HELLS", "HELZ", "HERC2", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HP1BP3", "HPRT1", "HPS6", "HS1BP3", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "ILF2", "ILF3", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPAD1", "IMPDH2", "INA", "INCENP", "INF2", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IRF2BPL", "IRS4", "ISCU", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPK1", "IVD", "JUP", "KARS", "KAT7", "KCTD12", "KCTD5", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM3B", "KDSR", "KHDRBS1", "KHSRP", "KIAA0368", "KIF11", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KLC1", "KLC2", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LAMP1", "LAMTOR1", "LAMTOR2", "LANCL1", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDAH", "LDHA", "LDHB", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC40", "LRRC47", "LRRC59", "LRWD1", "LSG1", "LSM14A", "LSM14B", "LSM2", "LSM6", "LSS", "LTA4H", "LTN1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LZTFL1", "M6PR", "MACF1", "MAK16", "MANF", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MCAT", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED17", "MED24", "MED25", "MEPCE", "MESD", "METTL1", "METTL13", "MFF", "MFN2", "MFSD10", "MFSD5", "MGEA5", "MGST2", "MGST3", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MIPEP", "MKI67", "MLEC", "MMAB", "MMGT1", "MMS19", "MOGS", "MORF4L1", "MOV10", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP2", "MPRIP", "MPST", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL28", "MRPL3", "MRPL37", "MRPL39", "MRPL40", "MRPL44", "MRPL45", "MRPL46", "MRPL58", "MRPL9", "MRPS15", "MRPS17", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTDH", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR6", "MTOR", "MTPAP", "MTPN", "MUT", "MVD", "MVK", "MYBBP1A", "MYEF2", "MYG1", "MYH10", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA25", "NAA40", "NAA50", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCAPH2", "NCBP1", "NCK1", "NCKAP1", "NCL", "NCLN", "NCOA5", "NCSTN", "NDC1", "NDUFA10", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NEDD4", "NEFL", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NFS1", "NHP2", "NIFK", "NIP7", "NIPA2", "NKRF", "NKTR", "NLN", "NLRX1", "NME1", "NME2", "NMT1", "NNT", "NOC2L", "NOC3L", "NOC4L", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOSIP", "NOVA2", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NSA2", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSUN2", "NSUN5", "NSUN6", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDT1", "NUDT12", "NUDT16L1", "NUDT21", "NUDT5", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP35", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC3", "OSBP", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OTULIN", "OXA1L", "OXSR1", "P3H1", "P4HA1", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAK2", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PASK", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF2", "PHF5A", "PHF6", "PHGDH", "PHIP", "PI4K2A", "PICALM", "PIGK", "PIGU", "PIH1D1", "PIK3C2A", "PIN1", "PIN4", "PINX1", "PIR", "PISD", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN2", "PLA2G15", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PMVK", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPO", "PNPT1", "POFUT1", "POLA1", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPHLN1", "PPIB", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R1", "PPP5C", "PPT1", "PPT2", "PQBP1", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA3", "PSMA4", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTRH2", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXN", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB21", "RAB24", "RAB34", "RAB35", "RAB39A", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB8B", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD51AP1", "RAE1", "RAI14", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP1GDS1", "RAPGEF2", "RARS", "RASA1", "RAVER1", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM8A", "RBMX", "RBMXL1", "RBP1", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "RER1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFLNB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIDA", "RMDN1", "RMDN3", "RNASEH2A", "RNASET2", "RNF114", "RNF14", "RNF40", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP1B", "RRP8", "RRP9", "RRS1", "RSBN1", "RSF1", "RSL1D1", "RTCB", "RTN4", "RTN4IP1", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMHD1", "SAP18", "SAR1A", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAMP1", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDCBP", "SDE2", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC63", "SEH1L", "SENP3", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD7", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN4", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIN3A", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC30A5", "SLC35A4", "SLC35B2", "SLC35F2", "SLC3A2", "SLC4A1AP", "SLC9A3R1", "SLFN11", "SLIRP", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMYD3", "SMYD5", "SNAP23", "SNAP29", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SOAT1", "SOD2", "SON", "SORD", "SPAG9", "SPART", "SPATA5L1", "SPC24", "SPCS2", "SPCS3", "SPEN", "SPOUT1", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STIM2", "STIP1", "STK4", "STMN1", "STOML2", "STRAP", "STRBP", "STRN", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX17", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SULT2A1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYNCRIP", "SYNE2", "TAB1", "TACO1", "TAF15", "TAGLN2", "TALDO1", "TAMM41", "TARDBP", "TARS", "TARS2", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF25", "TCOF1", "TCP1", "TDP2", "TDRKH", "TECR", "TELO2", "TERF2IP", "TES", "TEX264", "TFAM", "TFG", "TFRC", "THOC1", "THOC3", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "TIA1", "TIAL1", "TIMELESS", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TK1", "TKT", "TLN1", "TMCO1", "TMED10", "TMEM109", "TMEM192", "TMEM43", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TNPO1", "TNPO2", "TOE1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOR1AIP2", "TOX4", "TP53", "TP53BP1", "TPD52", "TPD52L2", "TPI1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRIM21", "TRIM25", "TRIM27", "TRIM28", "TRIP12", "TRIP13", "TRMT10C", "TRMT11", "TRMT112", "TRMT2A", "TRMT6", "TROVE2", "TRUB1", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPYL1", "TSR1", "TSTA3", "TTC1", "TTC26", "TTC4", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3C", "UBE4A", "UBLCP1", "UBR4", "UBR5", "UBTF", "UBXN1", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UFSP2", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRC1", "UQCRC2", "UQCRFS1", "URB1", "UROD", "USO1", "USP10", "USP11", "USP14", "USP19", "USP28", "USP33", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VPS18", "VPS35", "VPS4A", "VRK1", "VRK3", "WARS", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR3", "WDR33", "WDR36", "WDR41", "WDR43", "WDR46", "WDR5", "WDR6", "WDR75", "WDR77", "WDR82", "WFS1", "WIPI2", "WIZ", "WRAP53", "WTAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YKT6", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZDHHC13", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM4", "ZNF318", "ZNF326", "ZNF512B", "ZNF598", "ZNF622", "ZNF638", "ZPR1", "ZRANB2", "ZW10", "ZYX"], "leading_proteins": ["AARS2", "AATF", "ABCB10", "ABCB7", "ABCC1", "ABCC4", "ABCF1", "ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACOX1", "ACOX3", "ACTN2", "ADPGK", "AGL", "AHNAK", "AK1", "AKAP12", "AKT1", "AKT2", "ALDH18A1", "ALDH3A2", "ANKFY1", "ANKLE2", "ANXA11", "ANXA2", "AP1B1", "AP1G1", "AP2A2", "ARF4", "ARFIP1", "ARFIP2", "ARHGAP17", "ARPC3", "ASPM", "ATG4B", "ATIC", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5I", "ATP6", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATPIF1", "ATRX", "BAG4", "BAG6", "BAIAP2", "BASP1", "BAX", "BCAT2", "BCL10", "BLMH", "BRIX1", "BUD31", "CAB39", "CACYBP", "CAND1", "CARS", "CASP3", "CBFB", "CCNB1", "CD2AP", "CDC42", "CDC5L", "CDK13", "CDKN2A", "CDKN2AIP", "CDS2", "CENPV", "CERS2", "CGGBP1", "CHKA", "CHMP2A", "CHORDC1", "CIAPIN1", "CIRBP", "CMPK1", "CNNM3", "COASY", "COL4A3BP", "COX2", "COX4I1", "COX5B", "CPOX", "CPT2", "CSNK2A2", "CTBP2", "CXADR", "CYB5B", "CYP20A1", "CYP51A1", "DAXX", "DCAKD", "DCD", "DDRGK1", "DENR", "DERL1", "DHCR24", "DHFR", "DHX29", "DHX36", "DIAPH3", "DIP2B", "DLAT", "DLD", "DNAJA3", "DNAJB6", "DNAJC3", "DNM2", "DOHH", "DPYSL3", "DSP", "EARS2", "EDF1", "EHD1", "EIF3A", "EIF3F", "EIF3J", "EIF3M", "EIF4G1", "ELMO2", "ENSA", "EPPK1", "ERAL1", "ERAP1", "ERCC2", "ERCC6L", "ERGIC3", "ERP44", "ESYT1", "ESYT2", "EXOC2", "EXOC4", "EXOSC2", "EXOSC9", "EZR", "FABP5", "FAM98B", "FBL", "FH", "FKBP1A", "FKBP7", "FKBP8", "FKBP9", "FNTB", "FOXC1", "FUNDC2", "FXR2", "GAA", "GABARAPL2", "GAPDH", "GATAD2A", "GBA", "GCAT", "GCC2", "GGCT", "GGCX", "GLTP", "GLUD1", "GNG5", "GOLGB1", "GOT1", "GPT2", "GRHPR", "GTF2I", "H1F0", "H2AFY2", "HADHB", "HIST1H1C", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGN2", "HMOX1", "HMOX2", "HNRNPU", "HSD17B11", "HSPA1B", "HSPA8", "HSPB1", "IGF2BP2", "IPO11", "IPO8", "IQGAP1", "ISCU", "JUP", "KDM1A", "KIF1A", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIFBP", "KMT2A", "KNTC1", "KPNA1", "KPNA3", "KTN1", "LAMTOR1", "LANCL1", "LETM1", "LGALS3", "LIG1", "LLGL1", "LONP1", "LRPAP1", "LSM2", "M6PR", "MACF1", "MANF", "MAP2K2", "MAP3K7", "MAPK14", "MARK2", "MCCC2", "MCTS1", "MCU", "MDH1", "ME1", "ME2", "MECP2", "MED24", "MED25", "MEPCE", "MFN2", "MFSD10", "MIA3", "MIPEP", "MMGT1", "MOGS", "MRPL12", "MRPL14", "MRPL17", "MRPL19", "MRPL28", "MRPL44", "MRPL58", "MRPL9", "MRPS17", "MRPS23", "MRPS27", "MRPS28", "MRPS35", "MRPS5", "MSH2", "MSH6", "MSMO1", "MSN", "MTDH", "MTIF2", "MTOR", "MTPN", "MUT", "MYH10", "MYH9", "NCAPD3", "NCAPG", "NCL", "NCSTN", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF7", "NDUFB3", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV2", "NEFL", "NEFM", "NOLC1", "NOP53", "NOP58", "NPTN", "NRBP1", "NSF", "NSUN5", "NT5C3A", "NUBPL", "NUCB2", "NUDT5", "NUP188", "NUP58", "OCRL", "OGDH", "OGT", "OXA1L", "OXSR1", "PABPC1", "PAFAH1B2", "PAFAH1B3", "PAIP1", "PALLD", "PARK7", "PARP2", "PCBD1", "PCK2", "PCMT1", "PDCD5", "PDHB", "PDXK", "PFDN6", "PGK1", "PGRMC2", "PIGK", "PIH1D1", "PIN4", "PIR", "PITPNA", "PITPNB", "PKMYT1", "PLA2G15", "PLEC", "PLS1", "POLE", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2E", "PON2", "PPAT", "PPIL1", "PPM1F", "PPP2R5D", "PPP3CA", "PPP5C", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX5", "PRDX6", "PRKAG1", "PRKAR1A", "PRKRA", "PSMB2", "PSMB6", "PSMC1", "PSMC4", "PSMC5", "PSMC6", "PSMD10", "PSMD14", "PSMD4", "PSME4", "PSMG1", "PSMG3", "PTCD3", "PUS1", "PYGB", "PYGL", "QKI", "RABGAP1", "RACGAP1", "RANBP9", "RASA1", "RBP1", "RDH11", "RECQL4", "REXO2", "RFLNB", "RNF40", "ROCK2", "RPA3", "RPL10A", "RPL12", "RPL13", "RPL22", "RPL23", "RPL23A", "RPL27", "RPL29", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL38", "RPL7", "RPL7A", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS18", "RPS19", "RPS2", "RPS3A", "RPS6", "RPS7", "RPS8", "RPS9", "RPSA", "RREB1", "RUFY1", "RUVBL1", "RUVBL2", "S100A11", "SAE1", "SCAF1", "SCARB1", "SCARB2", "SCD", "SCO1", "SEC11A", "SEPT6", "SERPINB6", "SERPINH1", "SFXN4", "SGPL1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIN3A", "SLC1A5", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A21", "SLC25A22", "SLC25A26", "SLC25A32", "SLC29A1", "SLC30A5", "SLC35B2", "SLC35F2", "SLC3A2", "SLC9A3R1", "SLTM", "SMARCA1", "SNAP23", "SNAP29", "SNRPD1", "SNX1", "SNX6", "SOAT1", "SOD2", "SPAG9", "SPPL2A", "SPTBN1", "SRBD1", "SRP14", "SRP54", "SRP68", "SRP9", "SRPRA", "SSB", "SSBP1", "STAM", "STAT3", "STAU1", "STIM2", "STK4", "STOML2", "STT3B", "STUB1", "SUN1", "SURF4", "TAB1", "TFAM", "TFRC", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TLN1", "TMEM109", "TOMM22", "TOR1AIP1", "TOX4", "TP53", "TPP1", "TRAP1", "TRMT11", "TSG101", "TTYH3", "TUBB2A", "TUBB4A", "TUBB4B", "TUBGCP2", "TUBGCP3", "TWF1", "TWF2", "UBA2", "UBA3", "UBE2N", "UBE2S", "UBXN1", "UCK2", "UFD1", "UGP2", "UNC119", "UNC119B", "UNG", "UQCR10", "USP33", "VCP", "VDAC1", "VPS18", "VPS4A", "VRK1", "VRK3", "WBP2", "WFS1", "XPOT", "YARS2", "YKT6", "YME1L1", "YRDC", "YWHAE", "ZADH2", "ZC3H18", "ZDHHC13", "ZMPSTE24", "ZNF318", "ZNF512B"]} \ No newline at end of file diff --git a/msigdb_hp/advanced/idx2term.json b/msigdb_hp/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..8932e5742c062c7e7a9df3d047c0e2380b447f72 --- /dev/null +++ b/msigdb_hp/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Broad based gait", "1": "Absent thumb", "2": "Heterogeneous", "3": "Aplasia of the fingers", "4": "Developmental cataract", "5": "Absent hair", "6": "Adenocarcinoma of the intestines", "7": "Gastrointestinal carcinoma", "8": "Triphalangeal thumb", "9": "Osteosarcoma"} \ No newline at end of file diff --git a/msigdb_hp/advanced/plot_0.png b/msigdb_hp/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..df3c7d306ee735261f3c0245e8217ed5d970a0a3 --- /dev/null +++ b/msigdb_hp/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b0f86a07d6c5e1a2f4bdb6368c7a30280a73c80d6669e855160497412d940e1e +size 201418 diff --git a/msigdb_hp/advanced/plot_1.png b/msigdb_hp/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..b51f9159a9c2b51dcb791b712cb673b738a39e4f --- /dev/null +++ b/msigdb_hp/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:46253bfd607aa5eed6a0b43f9513224751560d2c8f3c8dfd9b7bd68453bd02af +size 193766 diff --git a/msigdb_hp/advanced/plot_2.png b/msigdb_hp/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..725fc9727f1814fdefa09cb42e2241a4b91526f7 --- /dev/null +++ b/msigdb_hp/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e9b195ce2bd35816e41411cfbe04f9ed514f6412bbcccbc0835337eaf3acd381 +size 203988 diff --git a/msigdb_hp/advanced/plot_3.png b/msigdb_hp/advanced/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..9de267b24d49aee03eb4fa5249df0abc986ed58a --- /dev/null +++ b/msigdb_hp/advanced/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:cbbe1906fefd60f442a16cb6e658d9e055012136b874a612cfb694c51fd03bb8 +size 195793 diff --git a/msigdb_hp/advanced/plot_4.png b/msigdb_hp/advanced/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..b0f9e79fcb31821c47e1986799dd6894a8f83c23 --- /dev/null +++ b/msigdb_hp/advanced/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b44ad89e7a76faf6396464d769a77774e993dd0b02881584ca13383562fbee63 +size 206632 diff --git a/msigdb_hp/advanced/plot_5.png b/msigdb_hp/advanced/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..f75074ee96eacaaf5249eb30d0506fa3037d8d3a --- /dev/null +++ b/msigdb_hp/advanced/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:702fd8af97e2ca92c12a5592bd4f1b8fa615cd78aa385887ea118d58578b0458 +size 194206 diff --git a/msigdb_hp/advanced/plot_6.png b/msigdb_hp/advanced/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..c8b4c745a819f94e2927a169d5222d2dfe3e2a85 --- /dev/null +++ b/msigdb_hp/advanced/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0fa32a4b09131e71c7212104a128cce15f5aa822e786e44b41353461e5fd68e8 +size 192407 diff --git a/msigdb_hp/advanced/plot_7.png b/msigdb_hp/advanced/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..0b6eb8b8216f20b6bd42ab7684aad3d70a930707 --- /dev/null +++ b/msigdb_hp/advanced/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a4b42c448092ac1b8eafd12e18f3d1ce3526a9df0041a75baf28f804a499ac7b +size 196118 diff --git a/msigdb_hp/advanced/plot_8.png b/msigdb_hp/advanced/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..7aade311d70ea800337c38e326e3dbec53351949 --- /dev/null +++ b/msigdb_hp/advanced/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ee70e21d0b234ae90864b9dca63f1bacbb4dd52f58577f46ca4cc0081c7a075c +size 194096 diff --git a/msigdb_hp/advanced/plot_9.png b/msigdb_hp/advanced/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..9e54d56f64159e4e65ee062613e7a7790d46aa3c --- /dev/null +++ b/msigdb_hp/advanced/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bc67a72adacabf6cae8e5647a8f3763c0f427027a2bbb2ade9747c1273a7579e +size 195423 diff --git a/msigdb_hp/basic/idx2term.json b/msigdb_hp/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..e78a71f17b7ca4763117f5686bb8f71bdfec97aa --- /dev/null +++ b/msigdb_hp/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Broad based gait", "1": "Absent thumb", "2": "Heterogeneous", "3": "Aplasia of the fingers", "4": "Developmental cataract", "5": "Absent hair", "6": "Adenocarcinoma of the intestines", "7": "Gastrointestinal carcinoma", "8": "Triphalangeal thumb", "9": "Osteosarcoma", "10": "Adenocarcinoma of the colon", "11": "Abnormal epidermal morphology", "12": "Insulin resistance", "13": "Limb undergrowth", "14": "Sparse or absent eyelashes", "15": "Anemia of inadequate production", "16": "Abnormal erythrocyte enzyme level", "17": "Abnormality of the thenar eminence", "18": "Abnormality of the musculature of the hand", "19": "Premature birth", "20": "Cerebral hypoplasia", "21": "Pure red cell aplasia", "22": "Cardiac arrest", "23": "Erythroid hypoplasia", "24": "Malignant genitourinary tract tumor", "25": "Short foot", "26": "Postural tremor", "27": "Developmental glaucoma", "28": "Partial duplication of the phalanx of hand", "29": "Abnormal hemoglobin", "30": "Action tremor", "31": "Webbed neck", "32": "Increased mean corpuscular volume", "33": "Abnormal odontoid tissue morphology", "34": "Abnormal number of erythroid precursors", "35": "Decreased activity of mitochondrial complex i", "36": "Myelodysplasia", "37": "Alopecia", "38": "Intracranial hemorrhage", "39": "Hyperkeratosis", "40": "Persistence of hemoglobin f", "41": "Ambiguous genitalia", "42": "Telangiectasia", "43": "Reticulocytopenia", "44": "Nonimmune hydrops fetalis", "45": "Aplasia hypoplasia of the thumb", "46": "Normochromic anemia", "47": "Neoplasm of the skeletal system", "48": "Neoplasm of the colon", "49": "Renal agenesis"} \ No newline at end of file diff --git a/msigdb_hp/basic/plot_0.png b/msigdb_hp/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..df645c90fc8234e050efdaffe24dc868abcaf931 --- /dev/null +++ b/msigdb_hp/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:cd918db11ccfba45baf9d86f7f257ead8de49a963f8afdc65566a1cd48c3a55e +size 135542 diff --git a/msigdb_hp/basic/plot_1.png b/msigdb_hp/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..567d18cdf617d0c1c849bbe4a23f8df3f430b0a5 --- /dev/null +++ b/msigdb_hp/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:30e7c0ce3af3969e2e412d542c5a9998b2a77f1a88c9c1a74e63fba4d62ea4fb +size 132420 diff --git a/msigdb_hp/basic/plot_10.png b/msigdb_hp/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..647baef6c748464859269d4fda0a6f04d22e6232 --- /dev/null +++ b/msigdb_hp/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:121980c16be7c5161ce986c739c4ec5e7decdedbb6a8cd65a748c68614085447 +size 136941 diff --git a/msigdb_hp/basic/plot_11.png b/msigdb_hp/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..50a09a684fbfe9d5dff7f9c72de19aef255d4f5c --- /dev/null +++ b/msigdb_hp/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fae4037be450602be5b7d10634cbe46baf205139d7d545cb277418f87a699f4f +size 136058 diff --git a/msigdb_hp/basic/plot_12.png b/msigdb_hp/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..e7cf0bb0a2bd79c68bd85dedd97e03addac63223 --- /dev/null +++ b/msigdb_hp/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a5b8f73b5a1e8510c528fbbbef994f43c9666f9500477653d2b0de95758d2831 +size 133002 diff --git a/msigdb_hp/basic/plot_13.png b/msigdb_hp/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..14323e56663e239ca5e3a1958ba2d7439003a33f --- /dev/null +++ b/msigdb_hp/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:aeba3c4efc4ca82aa12da42ebc5575f859c5e5cdecbea5b2f075c262043deddf +size 130161 diff --git a/msigdb_hp/basic/plot_14.png b/msigdb_hp/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..e953da1ece2126e13a8e53ba07e42d3fd949a354 --- /dev/null +++ b/msigdb_hp/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7f5a0920a49a02fe9866dbff5436c06f1d6def19991bb6f83bcbebf5bdbb2831 +size 133717 diff --git a/msigdb_hp/basic/plot_15.png b/msigdb_hp/basic/plot_15.png new file mode 100644 index 0000000000000000000000000000000000000000..1297c566d02c8a66c64e3a8525f0ab8f5938d272 --- /dev/null +++ b/msigdb_hp/basic/plot_15.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:705e02f84bf006b379ded24d121575b4881162d7895eee3d2a9b98af66a4ed19 +size 142560 diff --git a/msigdb_hp/basic/plot_16.png b/msigdb_hp/basic/plot_16.png new file mode 100644 index 0000000000000000000000000000000000000000..ea189a061d3173b29c70ae969a04225dbeeba1e5 --- /dev/null +++ b/msigdb_hp/basic/plot_16.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:64643161124332582aa49444edf1e5ba36c3253f28e1218bb6f58db1d26443cf +size 135945 diff --git a/msigdb_hp/basic/plot_17.png b/msigdb_hp/basic/plot_17.png new file mode 100644 index 0000000000000000000000000000000000000000..7b5586f67e1619244d3e2f24503eb78f84f3bace --- /dev/null +++ b/msigdb_hp/basic/plot_17.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ca693f5bc8e018aba5958b05c06538d6338246b38f975a72a836f54c3af67cdc +size 136708 diff --git a/msigdb_hp/basic/plot_18.png b/msigdb_hp/basic/plot_18.png new file mode 100644 index 0000000000000000000000000000000000000000..caed235c3c9f18de5c1efada0d2c8c87d6a19017 --- /dev/null +++ b/msigdb_hp/basic/plot_18.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:941d880ec3ae36a468f2e0fe590f6ed1554865c586506bf0f23c80a990e310b2 +size 143912 diff --git a/msigdb_hp/basic/plot_19.png b/msigdb_hp/basic/plot_19.png new file mode 100644 index 0000000000000000000000000000000000000000..8ce679405da9133c65ae2768fe663431a5866b9c --- /dev/null +++ b/msigdb_hp/basic/plot_19.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:52043feef04fc64aeb0d2f1f74cbf47c43b1c41e8956f9bdb7787c9bf56c5316 +size 138442 diff --git a/msigdb_hp/basic/plot_2.png b/msigdb_hp/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..7f0bce3cf4f009701c9a4b902df9056b86410449 --- /dev/null +++ b/msigdb_hp/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:eec0c4db030d55723c1a08632b6b1be936b03e3c476d59fd87b0e6e9f05b428d +size 133538 diff --git a/msigdb_hp/basic/plot_20.png b/msigdb_hp/basic/plot_20.png new file mode 100644 index 0000000000000000000000000000000000000000..b885485ec704b2bb10e3e9a31de668eb7e2d76a3 --- /dev/null +++ b/msigdb_hp/basic/plot_20.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f94cd66dd082bae32b699ee316fa14a9602ad4eee9b4fad3d485a433c8abe111 +size 132167 diff --git a/msigdb_hp/basic/plot_21.png b/msigdb_hp/basic/plot_21.png new file mode 100644 index 0000000000000000000000000000000000000000..ea7bad473ae1e0797384f68c0f76ea18ba6df1bb --- /dev/null +++ b/msigdb_hp/basic/plot_21.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:83aa9f2e5fe25781591256d4938f17de75da6df504c10f78d8d6999422387065 +size 132843 diff --git a/msigdb_hp/basic/plot_22.png b/msigdb_hp/basic/plot_22.png new file mode 100644 index 0000000000000000000000000000000000000000..e73f77e1ffc03b43bfa679993fe149e1fdbad526 --- /dev/null +++ b/msigdb_hp/basic/plot_22.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:61cb183c62ded1a9fe2ec5d748eeda96c8ecd7465a904f9aa3873061f83f50c7 +size 137072 diff --git a/msigdb_hp/basic/plot_23.png b/msigdb_hp/basic/plot_23.png new file mode 100644 index 0000000000000000000000000000000000000000..96ecdd27a84a488308117eda8b7b7eb28cb972ab --- /dev/null +++ b/msigdb_hp/basic/plot_23.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4bb35416690ac45ee89e1839ed7226e6099d73f535790a02c914a66666b0522e +size 132344 diff --git a/msigdb_hp/basic/plot_24.png b/msigdb_hp/basic/plot_24.png new file mode 100644 index 0000000000000000000000000000000000000000..af3827ea83b567f6595a5dbe632f424649e1f707 --- /dev/null +++ b/msigdb_hp/basic/plot_24.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:35027916b19b82ae335a3e5469444e0efb4083aa0078d60df9492412560d8d1e +size 134387 diff --git a/msigdb_hp/basic/plot_25.png b/msigdb_hp/basic/plot_25.png new file mode 100644 index 0000000000000000000000000000000000000000..38d93893a0e94998fc69ef8a35b4dab655c21ebb --- /dev/null +++ b/msigdb_hp/basic/plot_25.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bfbfccfdfa25b7d5e709f653314694a3956abc4ab6021004565302ab9a67bd1f +size 125216 diff --git a/msigdb_hp/basic/plot_26.png b/msigdb_hp/basic/plot_26.png new file mode 100644 index 0000000000000000000000000000000000000000..2f0f8526c2ba9e01c15a1e00efc5d1b9d88f0480 --- /dev/null +++ b/msigdb_hp/basic/plot_26.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4dd39030b38479d087f3454dc134dac7badc430a1d70cc010f1864ab8df12d70 +size 132276 diff --git a/msigdb_hp/basic/plot_27.png b/msigdb_hp/basic/plot_27.png new file mode 100644 index 0000000000000000000000000000000000000000..eed8069c725574acaa8e98c2fe2c942abc7c0dc9 --- /dev/null +++ b/msigdb_hp/basic/plot_27.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9b1c21ca49f2a4e90bcf8f9bd8a6df6b153b4bacf27e3dfa8bec9b157cab8e7f +size 133659 diff --git a/msigdb_hp/basic/plot_28.png b/msigdb_hp/basic/plot_28.png new file mode 100644 index 0000000000000000000000000000000000000000..39364eaf2edb67611b7e3f8158f82fa04493b548 --- /dev/null +++ b/msigdb_hp/basic/plot_28.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5771fe8b70bee040cb1a8e3178532e6c6ac573168a5d7b9198409a0829f5e3d7 +size 135529 diff --git a/msigdb_hp/basic/plot_29.png b/msigdb_hp/basic/plot_29.png new file mode 100644 index 0000000000000000000000000000000000000000..a2f377fef98e70a26439761e4254f2958aeb3099 --- /dev/null +++ b/msigdb_hp/basic/plot_29.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8ebb7812d46adb0fafaccae9c0121463d2e87a811d1edfc1caf7e39dd14a3d45 +size 133198 diff --git a/msigdb_hp/basic/plot_3.png b/msigdb_hp/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..3cfd3258ac4c4e5c1ba40a5764eac303f36ce5e6 --- /dev/null +++ b/msigdb_hp/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0b9e0588d818fcbc720c066db20664f15078945dbde814ac9d244abab9476b8a +size 135081 diff --git a/msigdb_hp/basic/plot_30.png b/msigdb_hp/basic/plot_30.png new file mode 100644 index 0000000000000000000000000000000000000000..c49cfdff88f59618a93ed4cbcbf455826800734f --- /dev/null +++ b/msigdb_hp/basic/plot_30.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:75e8e39a9fb10e6828fc2909e2a4daab0c76a2c4b0e150aba7915d7ceca836f2 +size 135938 diff --git a/msigdb_hp/basic/plot_31.png b/msigdb_hp/basic/plot_31.png new file mode 100644 index 0000000000000000000000000000000000000000..fc4c9184dbbfb0062ac13d291350546e167cb5ad --- /dev/null +++ b/msigdb_hp/basic/plot_31.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:41cc0085f8f0ef0daa5a6abd30abd41340cc38d607ff1a3b855ef1e3216f2ea2 +size 129745 diff --git a/msigdb_hp/basic/plot_32.png b/msigdb_hp/basic/plot_32.png new file mode 100644 index 0000000000000000000000000000000000000000..83af34374fa373ff763254e2c6d015c26e1654b7 --- /dev/null +++ b/msigdb_hp/basic/plot_32.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:de1f7b19a6ab624f687a229934e295f6855425f4a1acdccc55c0c575c19a6a3e +size 142046 diff --git a/msigdb_hp/basic/plot_33.png b/msigdb_hp/basic/plot_33.png new file mode 100644 index 0000000000000000000000000000000000000000..38bf1e11e8de2b2e88a4af55b93d44e8d1a5b06e --- /dev/null +++ b/msigdb_hp/basic/plot_33.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:42a659b2570fc0c184c942b1315a3502f05681f37413f00b14ed5c78f9c86f78 +size 143550 diff --git a/msigdb_hp/basic/plot_34.png b/msigdb_hp/basic/plot_34.png new file mode 100644 index 0000000000000000000000000000000000000000..97ee70aa3a972cc51fc0e80a03a856e1f59d39d9 --- /dev/null +++ b/msigdb_hp/basic/plot_34.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9e3269b41da76c2a061d5a0e441b71942052cafd8f32b8571f57005d8a344d38 +size 140795 diff --git a/msigdb_hp/basic/plot_35.png b/msigdb_hp/basic/plot_35.png new file mode 100644 index 0000000000000000000000000000000000000000..014c9b5b686a4164557bbbf9310aedc1974542aa --- /dev/null +++ b/msigdb_hp/basic/plot_35.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:84dd67d2af12b96f119dc5977926e1156f060ac7e602a9aa3367c96f5167dd75 +size 146214 diff --git a/msigdb_hp/basic/plot_36.png b/msigdb_hp/basic/plot_36.png new file mode 100644 index 0000000000000000000000000000000000000000..b583e89fe64b1c53a898b1da2c6a5697c297d1e3 --- /dev/null +++ b/msigdb_hp/basic/plot_36.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0ed823f4e70cd2556abde4dad43191b6418b80ec79ccd4274ba433dbbe80b25a +size 140684 diff --git a/msigdb_hp/basic/plot_37.png b/msigdb_hp/basic/plot_37.png new file mode 100644 index 0000000000000000000000000000000000000000..47cc72f13ef65673fab6f700b50e596ec74514cd --- /dev/null +++ b/msigdb_hp/basic/plot_37.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9a1ec6d54bd57f751aaf63ffb3ffa3ffafc99e9cfcb2676f89eb0da55e41149a +size 129062 diff --git a/msigdb_hp/basic/plot_38.png b/msigdb_hp/basic/plot_38.png new file mode 100644 index 0000000000000000000000000000000000000000..5ff01fb9813c49461eb20291a979a7b4f854f959 --- /dev/null +++ b/msigdb_hp/basic/plot_38.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ed806b3cf49511518f9e6faef194d0f37e503726ea72d95d45ce1c696e03af8b +size 131752 diff --git a/msigdb_hp/basic/plot_39.png b/msigdb_hp/basic/plot_39.png new file mode 100644 index 0000000000000000000000000000000000000000..63cf2049b81a274d37f294c84ed486ba6899dc00 --- /dev/null +++ b/msigdb_hp/basic/plot_39.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:982927e7cb85f1590bb0219d12017c94da50da01e49e965f74505b0fded82be3 +size 130616 diff --git a/msigdb_hp/basic/plot_4.png b/msigdb_hp/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..88d98502ddb9e7cc8f7bad148cb34a255429ec92 --- /dev/null +++ b/msigdb_hp/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:78d819f02c8acb611a12b346cc836a8b15195616278b3ded909cefc506da5a10 +size 133635 diff --git a/msigdb_hp/basic/plot_40.png b/msigdb_hp/basic/plot_40.png new file mode 100644 index 0000000000000000000000000000000000000000..af6542c4f20adb5654eebb1bd80b69d9bb645b85 --- /dev/null +++ b/msigdb_hp/basic/plot_40.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:45a8b755448e83e79f836f8d201baa38b81f0c95b2e745779aa3b0d9dbc816a0 +size 133377 diff --git a/msigdb_hp/basic/plot_41.png b/msigdb_hp/basic/plot_41.png new file mode 100644 index 0000000000000000000000000000000000000000..54ed18906ad32168a5f64ee05931bd0176ff6e2d --- /dev/null +++ b/msigdb_hp/basic/plot_41.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:741fe001f8dfb9397a856f149f3db454a4dca2f60f66002f67150dda9dbd3f2f +size 130597 diff --git a/msigdb_hp/basic/plot_42.png b/msigdb_hp/basic/plot_42.png new file mode 100644 index 0000000000000000000000000000000000000000..8c3654308fe278c2748188c8b03556ed8ac350c1 --- /dev/null +++ b/msigdb_hp/basic/plot_42.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:94f05ed6030fea4dd87997338d9294327603ce50791206780f1bdfb1bd6191fc +size 129106 diff --git a/msigdb_hp/basic/plot_43.png b/msigdb_hp/basic/plot_43.png new file mode 100644 index 0000000000000000000000000000000000000000..dfdcd29a9534bb728585ce93197121325f5b6f79 --- /dev/null +++ b/msigdb_hp/basic/plot_43.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1e8a352389e72ac18b7c00a758123444c7cb8dd4c851e175b141f7e268516d69 +size 128892 diff --git a/msigdb_hp/basic/plot_44.png b/msigdb_hp/basic/plot_44.png new file mode 100644 index 0000000000000000000000000000000000000000..5dcd09b3484f4a4a995af6244b9cea0aa24dc80c --- /dev/null +++ b/msigdb_hp/basic/plot_44.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a330583b809bcebb420b72fb7466b67ee6af2c7f72eb963322c116d5a090f628 +size 139867 diff --git a/msigdb_hp/basic/plot_45.png b/msigdb_hp/basic/plot_45.png new file mode 100644 index 0000000000000000000000000000000000000000..a0a7016de05464c757255aea20ccf37c9c93dd41 --- /dev/null +++ b/msigdb_hp/basic/plot_45.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d20bd4df3072699507c67c70593d9c5e9dc594d8bff8a102d87057fdfe398e9a +size 132819 diff --git a/msigdb_hp/basic/plot_46.png b/msigdb_hp/basic/plot_46.png new file mode 100644 index 0000000000000000000000000000000000000000..ecf8d92aa00260b75fdd7690af6e769bc75caf9d --- /dev/null +++ b/msigdb_hp/basic/plot_46.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8f43402aa0bb9956d8a3f2276f2e551632fe9dd4f5961726f1e60f430b755071 +size 129734 diff --git a/msigdb_hp/basic/plot_47.png b/msigdb_hp/basic/plot_47.png new file mode 100644 index 0000000000000000000000000000000000000000..b1fe981715c52d05755884385c0d859a06cd0f53 --- /dev/null +++ b/msigdb_hp/basic/plot_47.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0bbfdfb0ea753d54c885acdeada609105d83a46759a47d0c67da90e71ee5e963 +size 142444 diff --git a/msigdb_hp/basic/plot_48.png b/msigdb_hp/basic/plot_48.png new file mode 100644 index 0000000000000000000000000000000000000000..d3732ce445938b05856b89078952d1d7144f96a9 --- /dev/null +++ b/msigdb_hp/basic/plot_48.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:017e83e6ac4720b42dc8737a65110dd52f88596268cce20b6e39077715224212 +size 138219 diff --git a/msigdb_hp/basic/plot_49.png b/msigdb_hp/basic/plot_49.png new file mode 100644 index 0000000000000000000000000000000000000000..783417711173fe3980ef68bca6333570accfb88e --- /dev/null +++ b/msigdb_hp/basic/plot_49.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a9cbd408f6220656300244129a39507ebeb2c19f7bc558655ed2befa9fb09f5a +size 137202 diff --git a/msigdb_hp/basic/plot_5.png b/msigdb_hp/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..6442b721772e24dddae23b6e03effa0b1e3cf6aa --- /dev/null +++ b/msigdb_hp/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4fca4f1c252b2e69d5d423e80ea2aeb2d3eacb1f6f102310f9dcce014dcb4b36 +size 130521 diff --git a/msigdb_hp/basic/plot_6.png b/msigdb_hp/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..e6aa721ed4605093d08acf12b356fb4cdb1afc50 --- /dev/null +++ b/msigdb_hp/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:86bb504a3535cb61ebd616a94f397090470c61376cd2e5984e171bd44c03e470 +size 139474 diff --git a/msigdb_hp/basic/plot_7.png b/msigdb_hp/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..c2d090489fc30452a3b7b6bad0a527c21c70fe4f --- /dev/null +++ b/msigdb_hp/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6407c84465ef2dd67faad57707f65e83d31093edad444af9600af06978faf041 +size 138740 diff --git a/msigdb_hp/basic/plot_8.png b/msigdb_hp/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..fb79c864cdb276578baf878686e98c135fcb0f72 --- /dev/null +++ b/msigdb_hp/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:81e55898ac477a1c9bf98c78f19e78c5f29efdd67ed98f14c57faf3e300c5c4e +size 133309 diff --git a/msigdb_hp/basic/plot_9.png b/msigdb_hp/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..389542e9d3691955a484d5365d5494bb2f974d3f --- /dev/null +++ b/msigdb_hp/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2d95ae8b7c3822d9f20dae042f53146546486e2b5fd912f5522c8e99be63dbb3 +size 132994 diff --git a/msigdb_hp/consensus.joblib b/msigdb_hp/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..05ad29a1f1692fa1124382db2e8889b40362b198 --- /dev/null +++ b/msigdb_hp/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:69d6c571eb28536037522e9eb200312ff3e0e7450f4ed17981a0fec3923d837f +size 340051 diff --git a/msigdb_hp/df_merge.tsv b/msigdb_hp/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..2b74b7c3328e8d451936dbf99b000012f3e916a8 --- /dev/null +++ b/msigdb_hp/df_merge.tsv @@ -0,0 +1,23 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Broad based gait 5 21 2.592708933956402 0.0095223322094417 5.118932038834951 23.531553398058257 0.0861127575935981 0.6925990326159184 3.179566256253446 3.234593732770885 0.6376115348843531 0.2705376623750066 1.0 0.0039603320298963 0.0247132014905158 0.2151815117830888 0.1044140646883817 +Absent thumb 7 26 2.5650275989591265 0.0103167598537672 10.9126213592233 24.99757281553398 -0.6715988313825342 0.4253858781249786 4.7833789822362105 1.9576818895367625 1.2148477872836383 0.3497100090215405 1.0 0.1878492321971458 0.3352847751843267 0.0035604731218749 0.0009777273668075 +Heterogeneous 9 38 2.5259790394218022 0.0115376364744597 10.235436893203884 42.58009708737864 0.5995354724013603 0.4531415918363276 4.134323127398932 5.0637577656341985 1.0306945905630256 0.3367867805298957 1.0 0.0269450278079508 0.0088604123408042 0.0162089797746267 0.1226555262639161 +Aplasia of the fingers 7 27 2.492660878735124 0.0126789877616 11.563106796116504 27.52912621359223 -0.6857325111479152 0.4414775036638273 5.029852442222966 2.297450299195613 1.1591251161846992 0.3512478886867645 1.0 0.2327728239456267 0.4055306262621692 0.0099772578106287 0.0047560837227238 +Developmental cataract 15 53 2.4848190420983527 0.0129617303807234 12.62864077669903 54.79611650485437 0.0847262287195766 0.7025669302505823 6.115431308931496 4.043715544385182 0.6700782944931937 0.2937873644100157 1.0 0.4009047789919011 0.6341798311372397 0.0039066031469977 4.867680605895276e-05 +Absent hair 5 11 2.434772390115432 0.0149011596384169 3.0825242718446604 11.104368932038836 -0.203331274569079 0.542653393692068 2.244299236943429 0.9508710058227632 0.8453532605369335 0.2741176255917095 1.0 0.0104419310742173 0.0369002586596571 0.0418365587142148 0.0041975929860202 +Adenocarcinoma of the intestines 7 22 2.424739640172243 0.0153193689622781 9.817961165048544 23.133495145631063 -0.4723450275482979 0.4508190526442003 4.3925541277805715 1.8139546502813697 1.2296228934527935 0.3539411393556459 1.0 1.0 1.0 0.0014394742441475 0.0002333812241419 +Gastrointestinal carcinoma 8 30 2.396013749986892 0.0165744685443702 11.941747572815531 31.00728155339806 -0.4417574781665778 0.4858615066127348 5.144655522105915 3.18711687411544 1.1110226134317185 0.3428989881470664 1.0 1.0 0.4482275541264321 0.0038320188362103 0.0031359747602994 +Triphalangeal thumb 7 22 2.375583308474658 0.0175212366916097 9.701456310679612 23.740291262135923 -0.5086159584603737 0.4625380781014795 4.415407469518261 2.3447996400672646 1.1452290636928404 0.3457457067846529 1.0 1.0 1.0 0.0123575173674234 0.0065574427418938 +Osteosarcoma 6 24 2.293355197634337 0.0218275637774147 7.810679611650485 24.50485436893204 -0.0838667199897112 0.537481976720288 4.8958157807955995 1.9638667346862224 1.0473835773003686 0.3327269107782364 1.0 0.1444128696349771 0.2637098090419308 0.0071674542029393 0.0007756835718833 +Adenocarcinoma of the colon 6 20 2.2068123896065064 0.027327169123531 9.50485436893204 20.58009708737864 -0.5385965908043259 0.4099332106587272 4.098007534825994 1.3513359051095024 1.3067136508964234 0.352270731481182 1.0 1.0 1.0 0.0039305824197994 0.000264376379907 +Absent facial hair 4 9 2.1915268514406416 0.0284136888192363 2.6844660194174756 9.58980582524272 -0.1104796150559784 0.5116743434735078 2.00544197881632 0.8297812094161009 0.9282495706741122 0.2749683614188889 1.0 0.0043047615253927 0.0157589231505245 0.0125223856028154 0.0025979397125818 +Abnormal epidermal morphology 5 17 2.1654360857181487 0.0303543050718577 4.716019417475728 17.939320388349515 0.174215235977072 0.5180036624559629 2.3595366666310484 1.948040470331747 0.9178221827497226 0.2842129908772916 1.0 0.1878492321971458 0.0076479800169414 0.0035604731218749 0.0172327536012624 +Insulin resistance 6 15 2.1599734245817053 0.0307747269286853 4.893203883495145 17.235436893203882 0.3647291601873548 0.5615501127125616 2.8091826588633757 2.071631445976644 0.8180218744344488 0.3014855836090789 1.0 0.0205053650950358 0.0695826578056071 0.0242202741498734 0.0064277367357915 +Upper limb undergrowth 3 13 2.15399411742634 0.0312406332441872 5.026699029126213 18.953883495145632 -0.188336763145614 0.6261711920109428 2.568813291181458 3.909201178054704 0.7072264856929216 0.2725451052085523 1.0 0.2855170484549717 0.4830891503762058 0.5010040264145029 0.4405045662877335 +Limb undergrowth 7 39 2.102063226149711 0.0355477376670732 10.648058252427184 51.10436893203884 0.3980398713744312 0.5752346762319336 4.664982243954684 7.303495661229484 0.9215304205365352 0.3350258300048305 1.0 0.2111338255209101 0.5027449337075841 0.2581330093764964 0.6437372149492139 +Absent eyebrow 4 6 2.029800548761671 0.0423768171702283 1.616504854368932 5.856796116504855 0.1710478952721111 0.4357282403534577 1.4222638242951853 0.6871761741750441 1.0372799645170534 0.2627886615575673 1.0 0.0039064712270754 0.0143432947155656 0.0109201949227154 0.0020589587060794 +Sparse or absent eyelashes 6 23 2.0135298920572717 0.0440589135339981 6.395631067961165 24.711165048543688 -0.3058207481965072 0.5785560428354796 3.598311408161159 2.5172360404695047 0.8173285689963438 0.2997554272811599 1.0 0.0333019544595367 0.1085884617962232 0.055110987006947 0.0252744340494398 +Ventricular tachycardia 4 11 2.010392349103995 0.0443896796064684 3.029126213592233 13.262135922330096 0.686137979317516 0.4029577645071625 1.751317455154925 1.7554971361746374 0.9579673572740748 0.2804177345045502 1.0 0.1197698958477507 0.2215080089822307 0.0248436194903882 0.0081448750398107 +Anemia of inadequate production 13 63 1.9768898166859008 0.0480540861468299 15.04126213592233 64.9004854368932 -0.059965564907005 0.6963281176328467 8.279448551076667 5.258585190995099 0.6981514136035563 0.2988083035837467 1.0 0.4657724234841013 0.3443377334426622 0.0126706082232288 0.0015141582416418 +Alopecia totalis 3 6 1.9712983085789983 0.0486897647238944 1.577669902912621 5.660194174757281 0.2360895211572874 0.4301462635410513 1.3973923036353155 0.7078395690409284 1.0489709738148425 0.2683714195722722 1.0 0.0011617774889038 0.0043816077243747 0.0018476819527472 0.001286883030813 +Aplasia hypoplasia of the ulna 1 8 1.9600871900361476 0.0499856002310834 3.3810679611650487 11.553398058252426 -0.3220657816526812 0.5735685967308073 2.0152165860237363 2.7798797045280064 0.7773930259924812 0.2876123638360858 1.0 0.2068720246493716 0.3654998372400087 0.3212350118353403 0.68534694154723 diff --git a/msigdb_hp/metrics.json b/msigdb_hp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..e8f0f51a1b8a1563d9244f3adea4c669c5f39bec --- /dev/null +++ b/msigdb_hp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2772, + "annotations_size": 4518, + "title": "Average number of proteins per term", + "value": 20.88645418326693 +} \ No newline at end of file diff --git a/msigdb_hp/paths.json b/msigdb_hp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..e9ce2b837e29ea4c3f86a6ec05881acaaee1ac20 --- /dev/null +++ b/msigdb_hp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_hp/fragment/C321/C321_val_log2fc"} \ No newline at end of file diff --git a/msigdb_hp/result.tsv b/msigdb_hp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..4502d74bd12e31071167da64c0bd76446850a342 --- /dev/null +++ b/msigdb_hp/result.tsv @@ -0,0 +1,1276 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Broad based gait 0.6874854819077388 2.592708933956402 0.0095223322094417 1.0 0.118347267674688 21 Q03164,P49589,Q9Y5P4,P51608,O14773 5 +Absent thumb 0.654721816606545 2.5650275989591265 0.0103167598537672 1.0 0.1246286658270598 26 P62244,P61353,P42766,O94761,P18077,Q15427,P62899 7 +Hand oligodactyly 0.95884476534296 2.5302450950956263 0.0113982873636608 1.0 0.1351639430682936 2 O94761 1 +Heterogeneous 0.5522320055316152 2.5259790394218022 0.0115376364744597 1.0 0.1354958118776426 38 O75844,P31749,P07196,Q9NWH9,P04792,Q9HCC0,P46100,P00846,P51608 9 +Aplasia of the fingers 0.6367569045873195 2.492660878735124 0.0126789877616 1.0 0.142370164169587 27 P62244,P61353,P42766,O94761,P18077,Q15427,P62899 7 +Abnormal motor evoked potentials 0.9494584837545126 2.4897617265729757 0.0127828761577206 1.0 0.142370164169587 2 Q9UNE7 1 +Developmental cataract 0.5246894207674285 2.4848190420983527 0.0129617303807234 1.0 0.142370164169587 53 Q01968,P62244,P61353,P42766,Q99797,P39019,O94761,Q9NVI7,P18077,O76024,Q15800,P36507,Q71SY5,Q5SRE5,P62899 15 +Absent hair 0.8209339166692687 2.434772390115432 0.0149011596384169 1.0 0.1557499199853343 11 O75844,Q9H9Y6,P14923,O94761,P15924 5 +Ulnar claw 0.9364620938628156 2.4334415572989525 0.014956049619291 1.0 0.1557499199853343 2 P07196 1 +Adenocarcinoma of the intestines 0.6544581887348686 2.424739640172243 0.0153193689622781 1.0 0.1580203401177458 22 P62244,P61353,P42766,P18077,Q13043,P62899,Q07864 7 +Sirenomelia 0.9306859205776166 2.40831155159398 0.0160264978537101 1.0 0.1619859447495802 2 P31749 1 +Vascular tortuosity 0.9303249097472917 2.4067389144038356 0.0160956721599068 1.0 0.1623219795054888 2 P00846 1 +Buphthalmos 0.9292418772563168 2.402019584911644 0.0163048354643475 1.0 0.1640651372559518 2 P31749 1 +Gastrointestinal carcinoma 0.6029626520319872 2.3960137499868916 0.0165744685443702 1.0 0.1660743402208116 30 P62244,P61353,P31749,P42766,P18077,Q13043,P62899,Q07864 8 +Triphalangeal thumb 0.6463224136734487 2.375583308474658 0.0175212366916097 1.0 0.1705482824480706 22 P21281,P62244,P61353,P42766,P18077,Q15427,P62899 7 +Ulcerative colitis 0.9209386281588448 2.365767560313208 0.01799273688738 1.0 0.1744446035561864 2 O43318 1 +Paroxysmal ventricular tachycardia 0.91624548736462 2.345222309907966 0.0190157376531643 1.0 0.1797345245125449 2 P04899 1 +Hypovolemic shock 0.9083032490974724 2.3103635130901012 0.0208680373476832 1.0 0.1927998862922605 2 P14923 1 +2 3 finger syndactyly 0.9083032490974724 2.3103635130901012 0.0208680373476832 1.0 0.1927998862922605 2 P14923 1 +3 4 finger syndactyly 0.9083032490974724 2.3103635130901012 0.0208680373476832 1.0 0.1927998862922605 2 P14923 1 +Patchy palmoplantar hyperkeratosis 0.9083032490974718 2.3103635130900972 0.0208680373476835 1.0 0.1927998862922605 2 Q06136 1 +Osteosarcoma 0.6233279846382143 2.293355197634337 0.0218275637774147 1.0 0.1996294193246154 24 P62244,P61353,P42766,O94761,P18077,P62899 6 +Hematemesis 0.8981949458483751 2.265835532656412 0.0234614549419531 1.0 0.208249220879655 2 P46100 1 +Protracted diarrhea 0.8981949458483751 2.265835532656412 0.0234614549419531 1.0 0.208249220879655 2 P46100 1 +Abnormal right ventricular function 0.8981949458483751 2.265835532656412 0.0234614549419531 1.0 0.208249220879655 2 P46100 1 +Abnormal bowel sounds 0.8981949458483751 2.265835532656412 0.0234614549419531 1.0 0.208249220879655 2 P46100 1 +Zollinger ellison syndrome 0.8981949458483751 2.265835532656412 0.0234614549419531 1.0 0.208249220879655 2 P46100 1 +Small cerebral cortex 0.894584837545125 2.249889005693622 0.0244559920312328 1.0 0.2149653151694745 2 Q8IZT6 1 +Adenocarcinoma of the colon 0.6336918013925973 2.2068123896065064 0.027327169123531 1.0 0.2291040258062638 20 P62244,P61353,P42766,P18077,P62899,Q07864 6 +Absent facial hair 0.8212078357187608 2.1915268514406416 0.0284136888192363 1.0 0.2343454816852298 9 O75844,O94761,P14923,P15924 4 +Paronychia 0.877617328519855 2.174636631161973 0.0296573570181437 1.0 0.2414269171314838 2 Q12756 1 +Moderate albuminuria 0.877617328519855 2.174636631161973 0.0296573570181437 1.0 0.2414269171314838 2 Q5JRA6 1 +Abnormal epidermal morphology 0.6566321643349199 2.1654360857181487 0.0303543050718577 1.0 0.2462131962561102 17 O75844,P20936,P31749,Q06136,P14923 5 +Insulin resistance 0.6715604340989652 2.1599734245817053 0.0307747269286853 1.0 0.2477284648077308 15 O75844,O95140,Q9Y6M1,P31751,P40763,P17096 6 +Upper limb undergrowth 0.7050005233092878 2.15399411742634 0.0312406332441872 1.0 0.2497987242458221 13 Q15427,O60762,O94761 3 +Limb undergrowth 0.5003381492094078 2.102063226149711 0.0355477376670732 1.0 0.2649925344493097 39 Q15392,Q03164,O94761,O60762,Q15427,Q96HY6,Q07864 7 +Absent eyebrow 0.8653559577000964 2.029800548761671 0.0423768171702283 1.0 0.2984092122045554 6 O75844,O94761,P14923,P15924 4 +Sparse or absent eyelashes 0.5837465161609479 2.0135298920572713 0.0440589135339981 1.0 0.3067152100872167 23 O75844,Q9H9Y6,P14923,O94761,Q15427,P15924 6 +Ventricular tachycardia 0.7290038583229417 2.010392349103995 0.0443896796064684 1.0 0.3075959700337798 11 P14923,Q9NX14,P04899,P15924 4 +Anemia of inadequate production 0.4485753673196799 1.9768898166859012 0.0480540861468299 1.0 0.322119230283943 63 Q96JJ3,P62244,O75027,P61353,Q9UBX3,P42766,P00374,P18077,Q6P4A7,P46100,Q9BQT8,Q9UER7,P62899 13 +Muscular ventricular septal defect 0.8324909747292406 1.972157674876234 0.0485916096756391 1.0 0.3247737311252699 2 Q5SRE5 1 +Alopecia totalis 0.8504931890222271 1.9712983085789983 0.0486897647238944 1.0 0.3247737311252699 6 O75844,O94761,P14923 3 +Aplasia hypoplasia of the ulna 0.7920859969172069 1.9600871900361472 0.0499856002310834 1.0 0.3276385110943483 8 O94761 1 +Absent forearm bone 0.8683217968747318 1.956801686943928 0.0503707886756203 1.0 0.3276385110943483 5 O94761 1 +Round face 0.6185336444551525 1.9511844484327496 0.0510351082710354 1.0 0.3307168398860468 17 Q03164 1 +Abnormality of the endometrium 0.8150034503167443 1.9398469753185177 0.0523982897828019 1.0 0.3329612844426147 7 P31749 1 +Aplasia hypoplasia involving forearm bones 0.6625498129743336 1.937027018688954 0.0527420407111365 1.0 0.3337245544249481 13 Q15427,O94761 2 +Aplasia hypoplasia of the radius 0.6625498129743336 1.937027018688954 0.0527420407111365 1.0 0.3337245544249481 13 Q15427,O94761 2 +Abnormal erythrocyte enzyme level 0.5857324886263896 1.9183219339160855 0.0550702029008256 1.0 0.3403654948097541 20 P62244,P61353,P42766,P18077,Q96RL7,P62899 6 +Coronal craniosynostosis 0.8342174258216712 1.9068544467071904 0.0565394384785125 1.0 0.3466013338479233 6 O94761 1 +Calcinosis 0.8533522793844892 1.8990214553367983 0.0575616550739996 1.0 0.3489513164337604 5 O94761 1 +Generalized hirsutism 0.5603895127930597 1.8893360386361715 0.0588468154554413 1.0 0.3512152076983936 24 Q03164,P31749 2 +Oligodactyly 0.8496896849715986 1.8848374320309311 0.0594517895378576 1.0 0.3543577640264393 5 O94761 1 +Abnormal forearm bone morphology 0.626384828416729 1.882759319573424 0.0597329923706901 1.0 0.3550969204352345 14 Q15427,O94761 2 +Urogenital fistula 0.7722861347476124 1.8757356844431607 0.0606915833264491 1.0 0.3589025297522475 8 O94761,Q01968 2 +Optic neuropathy 0.5854793381990537 1.8604840531452131 0.0628170725645367 1.0 0.3664332405613605 19 O75489,O43676,Q86Y39,P00846 4 +Blepharophimosis 0.4705294228609483 1.8470259653582517 0.0647433771876311 1.0 0.3731002272113742 39 O94761,Q03164 2 +Abnormality of the thenar eminence 0.5916344210617525 1.8450600941262725 0.0650287973653567 1.0 0.3742676515881294 18 P62244,P61353,P42766,P18077,P62899 5 +Neonatal insulin dependent diabetes mellitus 0.8036101083032474 1.8409298227241797 0.0656318434027527 1.0 0.3766628432914465 2 P40763 1 +Narrow palpebral fissure 0.612451307597389 1.837762805934831 0.0660973645660094 1.0 0.3784890913931948 15 Q03164 1 +Choanal stenosis 0.8353487436277024 1.829126770115953 0.0673806194786648 1.0 0.3834076055473647 5 O94761,Q9H9Y6 2 +Abnormality of the musculature of the hand 0.4981150484720102 1.823501006287912 0.0682275448043752 1.0 0.3867654296438735 34 O43318,P62244,P61353,P42766,P39019,P07196,P18077,Q9BQT8,P62899 9 +Hyperactive deep tendon reflexes 0.812416069396029 1.8199321351112996 0.0687693404396412 1.0 0.3883853202550008 6 Q9UNE7 1 +Premature birth 0.4758237468144775 1.8199199627308904 0.0687711943789288 1.0 0.3883853202550008 37 O75844,P22570,O43676,Q15427,P36507,Q9NX14 6 +Cerebral hypoplasia 0.6144330224849678 1.8176963083494728 0.069110562304558 1.0 0.3897646954060738 14 P42695,Q13057,P22570,Q8IZT6,O60762 5 +Pure red cell aplasia 0.568782590118974 1.814519050459242 0.0695978525185601 1.0 0.3910983801975802 20 P62244,P61353,P42766,P18077,P62899 5 +Cardiac arrest 0.5343565148306726 1.806699308018656 0.0708091756632365 1.0 0.3964260912596067 27 P31749,P14923,P35609,P04899,Q9NX14,P15924 6 +Lacticaciduria 0.8292929584357656 1.8055207833774405 0.0709932262523769 1.0 0.3969645992676224 5 P00846 1 +Erythroid hypoplasia 0.5743514471365994 1.793687281105068 0.0728630965265231 1.0 0.4001060812315424 19 P62244,P61353,P42766,P39019,P62263,P18077,P62899 7 +Central scotoma 0.7299797194586345 1.791813256909655 0.0731628845335539 1.0 0.4006665603910261 9 P00846 1 +Progeroid facial appearance 0.8050963275349099 1.7906001634874111 0.0733574807967205 1.0 0.4012458816459848 6 O75844 1 +Malignant genitourinary tract tumor 0.5635314983565286 1.7821800993010406 0.0747198669962236 1.0 0.4057225456677469 20 P62244,P61353,P42766,P18077,P62899 5 +Short foot 0.5433074738084553 1.7771765133591615 0.0755392024536107 1.0 0.4082369816811166 24 O43318,O94761,Q9Y5P4,Q96A33,P51608 5 +Anteriorly placed anus 0.6784026888174127 1.7688557119241275 0.0769179566564299 1.0 0.4137087240163697 11 O94761 1 +Juvenile cataract 0.7970217481042033 1.758160397254873 0.0787202215330389 1.0 0.418242194997082 6 O94761 1 +Capillary hemangioma 0.7441357922016253 1.7547090723250764 0.0793090834191301 1.0 0.4184507715853552 8 P21281,O94761,P31749 3 +Aplasia hypoplasia of the ribs 0.5902606458596542 1.745966498868405 0.0808167733462656 1.0 0.4235848978868078 16 Q96HY6,P21281,Q15427,Q03164 4 +Abnormal morphology of the radius 0.67257795552362 1.7407257543302836 0.081731661642443 1.0 0.4271175270869911 11 Q15427,O94761 2 +Postural tremor 0.5793105043083142 1.7261519324971026 0.0843200829900605 1.0 0.4348837156953123 17 P04350,O75306,P00846,Q9UNE7,O95140,O14773 6 +Abnormality of fibula morphology 0.6915126186528129 1.7208447390002688 0.0852790015467563 1.0 0.4360144286731702 10 Q15427,Q9NWH9 2 +Developmental glaucoma 0.5219153985485905 1.7205833285663117 0.0853264608218089 1.0 0.4360144286731702 27 Q01968,P62244,P31749,P61353,P42766,P18077,P62899 7 +Shock 0.8070593431496145 1.718459011332084 0.085712924627197 1.0 0.4365851110097815 5 P14923,P46100,P15924 3 +Progressive proximal muscle weakness 0.7765342960288786 1.7169028180968138 0.0859969299175515 1.0 0.4367686573566575 2 Q7Z392 1 +Abnormal vagina morphology 0.617796488756294 1.7034879302680397 0.0884767948424305 1.0 0.4438172174618969 13 O94761,Q9H9Y6 2 +Hypoplasia of the radius 0.7320807583980096 1.7025114772992724 0.0886595288003828 1.0 0.4438172174618969 8 Q15427,O94761 2 +Abnormal visual field test 0.8027442634368043 1.7014935258542754 0.0888503525015154 1.0 0.4438172174618969 5 P00846 1 +Partial duplication of the phalanx of hand 0.5503837247631188 1.700856431934429 0.0889699494839324 1.0 0.4438172174618969 20 P62244,P61353,P42766,P18077,P62899 5 +Abnormal urine ph 0.4533067669743682 1.6976162099214949 0.0895802213651522 1.0 0.4438172174618969 39 Q9HCC0,P00846 2 +Absent toenail 0.7565192992530515 1.6974773260169351 0.0896064542691159 1.0 0.4438172174618969 7 P21281,P14923 2 +Depressed nasal tip 0.9331938170942204 1.6952705423895913 0.090024110269546 1.0 0.4438172174618969 4 Q03164 1 +Abnormal hemoglobin 0.5308377011596188 1.6947080469335942 0.0901308184020017 1.0 0.4438172174618969 24 P62244,P61353,P42766,P18077,P46100,P62899 6 +Spastic paraparetic gait 0.7707581227436802 1.6903350912216504 0.0909638652876752 1.0 0.4438172174618969 2 Q12756 1 +Alveolar ridge overgrowth 0.770397111913355 1.6886734638911791 0.0912820236423352 1.0 0.444409679758697 2 Q15392 1 +Action tremor 0.4434535970478638 1.6787212411574166 0.0932063842268502 1.0 0.4494198974780249 49 O75027,P31749,P00846,Q8N2K0,O14773 5 +Biventricular hypertrophy 0.7667870036101059 1.6720500449447429 0.0945144540819407 1.0 0.4505794773791077 2 P37837 1 +Webbed neck 0.4654720981013073 1.6716553173320334 0.0945923099213739 1.0 0.4505794773791077 36 O95202,O75844,O43318,Q03164,P62244,P61353,P42766,P18077,P36507,P62899 10 +Increased mean corpuscular volume 0.5335053132905735 1.6685537194873905 0.0952058573103245 1.0 0.4509166076731885 22 P62244,P61353,P42766,P39019,P18077,P62899 6 +Vaginal fistula 0.748874423704267 1.6654419340739788 0.0958246191299903 1.0 0.4528615368507282 7 O94761 1 +Sparse eyelashes 0.5685980055227028 1.663988432448319 0.0961147410710547 1.0 0.4537579938965783 17 Q15427,O75844,O94761 3 +Congenital localized absence of skin 0.7646209386281565 1.6620699044127047 0.0964987590737469 1.0 0.4539690450287253 2 Q15149 1 +Aplasia cutis congenita over the scalp vertex 0.7646209386281565 1.6620699044127047 0.0964987590737469 1.0 0.4539690450287253 2 Q15149 1 +Abnormal odontoid tissue morphology 0.4711227288407907 1.661757703033332 0.0965613661515283 1.0 0.4539690450287253 35 Q01968,Q9H9Y6,P31749,P51648,O94761,Q9NX14,Q5JRA6 7 +Abnormal number of erythroid precursors 0.5217579050298086 1.6596191332736423 0.0969910967594838 1.0 0.4546975552585857 25 P62244,P61353,P42766,P39019,P62263,P18077,Q9Y606,P62899 8 +Abnormality of the distal phalanges of the toes 0.791596880773961 1.6575682922311463 0.0974046340342096 1.0 0.4560353746803721 5 O75844 1 +Abnormality of pulmonary circulation 0.5212618520851889 1.6562711524816405 0.0976669196937325 1.0 0.4566960201185512 25 O75844,Q9NZ08,P31749 3 +Decreased activity of mitochondrial complex i 0.4934487864387207 1.6504747556024886 0.0988458724014103 1.0 0.4598031401666205 31 O75306,P51970,Q8TB37,Q9UBX3,O75489,P19404,O43676,Q86Y39,Q9Y3D9,Q5T440,Q70HW3,Q9H0R6,O75251,Q96EY7,P52815,Q9NX14,Q9Y584,Q5JPH6 18 +Myelodysplasia 0.446984553617306 1.6501033920455286 0.0989217911115438 1.0 0.4598031401666205 41 P62244,P61353,P42766,O94761,P18077,P46100,P62899 7 +Hypoplasia of teeth 0.5578616244287818 1.6455745639922277 0.0998513795432938 1.0 0.4626959310529245 18 O75844,O94761,Q01968 3 +Zonular cataract 0.6515188513317542 1.638519288172231 0.1013134137994242 1.0 0.4651768328717467 11 O94761,Q01968,Q99797 3 +Alopecia 0.4463166062254083 1.636613684299219 0.1017112145027308 1.0 0.4657692896312966 39 O75844,Q06136,P14923,O94761,Q10567,Q9HCC0,Q9UNE7,P15924 8 +Primary hypercortisolism 0.7588447653429579 1.6354349165760018 0.1019579078010961 1.0 0.4657692896312966 2 P17612 1 +Adrenocortical abnormality 0.7588447653429579 1.6354349165760018 0.1019579078010961 1.0 0.4657692896312966 2 P17612 1 +Mild postnatal growth retardation 0.7588447653429577 1.6354349165760018 0.1019579078010961 1.0 0.4657692896312966 2 Q9Y3E5 1 +Macrovesicular hepatic steatosis 0.78535173778214 1.6329009257923128 0.1024898354175527 1.0 0.4665616586351489 5 P23786,Q5JPH6 2 +Aplasia hypoplasia involving bones of the thorax 0.5174986354592113 1.6308503289941632 0.1029219047460063 1.0 0.467337854917042 25 Q15427,O75844,Q96HY6,Q03164 4 +Intracranial hemorrhage 0.5232306164982288 1.6217271122570316 0.1048617909323015 1.0 0.4683556269081501 23 O75844,P20936,P07954,P31749,P22033,P23786 6 +Arterial thrombosis 0.7629752125446305 1.6204841602991835 0.1051283141740233 1.0 0.4683556269081501 6 P31749 1 +Tubulointerstitial nephritis 0.7815722864857955 1.617952974896424 0.1056727323765307 1.0 0.4683556269081501 5 P23786,Q9Y276 2 +Hyperkeratosis 0.4287092452163378 1.6163172732132751 0.1060257341136559 1.0 0.4683556269081501 55 O75844,Q96JJ3,P31749,Q06136,P51648,P14923,O94761,Q10567,P36507,P35609,Q9P265,P15924 12 +Abnormal morphology of myocardial trabeculae 0.7809715915453923 1.615575855899268 0.1061860475182561 1.0 0.4683556269081501 5 P35609,P14923 2 +Rectal fistula 0.7609989328789472 1.6124514396371648 0.1068637389176641 1.0 0.4683556269081501 6 O94761 1 +Intestinal fistula 0.7609989328789472 1.6124514396371648 0.1068637389176641 1.0 0.4683556269081501 6 O94761 1 +Hemihypertrophy 0.9263271939328296 1.610546832473825 0.1072785300959753 1.0 0.4683556269081501 3 P20936,P31749 2 +Venous thrombosis 0.576756880086875 1.6103429637630733 0.1073230047065334 1.0 0.4683556269081501 14 Q9NZ08,P31749 2 +Persistence of hemoglobin f 0.5357412697450431 1.6097372945927164 0.1074552195202396 1.0 0.4683556269081501 20 P62244,P61353,P42766,P18077,P62899 5 +Ambiguous genitalia 0.5592512365225824 1.609532509070329 0.107499952435536 1.0 0.4683556269081501 17 Q15392,P21281,P22570,P46100,Q9NX14 5 +Telangiectasia 0.4869221729922484 1.601628312294969 0.1092378261852662 1.0 0.4724480085116272 31 P20936,P31749,O94761,O60762,P46100,P00846,Q9UER7,Q13043,Q07864 9 +Reticulocytopenia 0.5332836790948395 1.5943917406266022 0.1108483211814976 1.0 0.4757695706576222 20 P62244,P61353,P42766,P18077,P62899 5 +Absent sternal ossification 0.7498194945848349 1.5937605098025218 0.1109896855779855 1.0 0.4757695706576222 2 Q9Y619 1 +Nonimmune hydrops fetalis 0.5032117525173965 1.590226580263016 0.111783741140597 1.0 0.476347524894866 27 P20936,P62244,P61353,P42766,P10619,P39019,Q9H0R6,P18077,P62899 9 +Aplasia hypoplasia involving the nose 0.5030992761810388 1.5894397762744326 0.1119611404319558 1.0 0.476347524894866 27 O75844,Q96ST3,O94761 3 +Keratosis pilaris 0.7487364620938601 1.5887552702452388 0.1121156553518822 1.0 0.476347524894866 2 Q9UQ13 1 +Aplasia hypoplasia of the thumb 0.4388575270373994 1.5879530611223902 0.1122969536147038 1.0 0.476347524894866 43 O95202,P21281,O43318,P62244,P61353,P42766,Q96ST3,O94761,P18077,Q15427,P62899 11 +Abnormality of the epiphyses of the distal phalanx of finger 0.7483754512635353 1.5870866642186 0.1124930178153174 1.0 0.476347524894866 2 Q9Y2Q9 1 +Dystrophic fingernails 0.7052352440580519 1.5855570305034796 0.1128398301728612 1.0 0.4773505175290141 8 O75844,P40763,P36507,Q12756 4 +Microcytic anemia 0.7044097438387308 1.581946322396151 0.113661824886591 1.0 0.4799290886332881 8 Q9BQT8,O75027,P46100 3 +Normochromic anemia 0.5166996375526628 1.578789277426767 0.1143843988675783 1.0 0.4808499830155535 23 P62244,P61353,P42766,P18077,P62899 5 +Abnormal bronchus physiology 0.770057770483962 1.5723253510428687 0.1158751166473828 1.0 0.4827062802241803 5 Q9H0U9,Q9UER7,P46100 3 +Bronchospasm 0.770057770483962 1.5723253510428687 0.1158751166473828 1.0 0.4827062802241803 5 Q9H0U9,Q9UER7,P46100 3 +Undetectable visual evoked potentials 0.7447653429602863 1.5703954719113318 0.116323135251124 1.0 0.4834847516693453 2 Q8TC12 1 +Prominent antitragus 0.7447653429602861 1.5703954719113318 0.116323135251124 1.0 0.4834847516693453 2 Q92643 1 +Facial capillary hemangioma 0.914496396203618 1.567140250259868 0.1170819127920332 1.0 0.4857447952198405 3 O94761 1 +Neoplasm of the skeletal system 0.4369286133018263 1.565490283762667 0.1174679938400338 1.0 0.486703382130694 42 P62244,P61353,Q9H9Y6,P31749,P42766,O94761,P18077,P62899 8 +Bilateral ptosis 0.6138415656533254 1.5628708501622537 0.1180829752429875 1.0 0.4879556666507953 12 P21281,P40763,Q9Y5P4 3 +Neoplasm of the colon 0.4651140188186631 1.562415220313561 0.1181902038185924 1.0 0.4879556666507953 34 P62244,P61353,Q8WX93,P42766,P39019,P62081,P18077,P62899,Q07864 9 +Lower limb pain 0.7483669347510904 1.5610121496711735 0.1185208842279226 1.0 0.4882520616343282 6 P20936,O95140,P00846 3 +Narrow nasal ridge 0.6995052672482811 1.5604781252847266 0.1186469353402084 1.0 0.4882520616343282 8 O75844,Q53EZ4,P32322 3 +Renal agenesis 0.4334695750821104 1.5590892932174456 0.1189752474093119 1.0 0.4886637889047923 46 Q15392,P42695,O75306,P62244,Q8IZT6,P61353,P42766,P39019,P54886,P18077,Q9Y2W2,Q15427,P46100,Q86XL3,P62899,P18583 16 +Short thumb 0.4371631224791727 1.5541861914575332 0.1201400103238938 1.0 0.490904009586989 38 O95202,P21281,O43318,P62244,P61353,P42766,Q96ST3,O94761,P18077,P62899 10 +Abnormality of the ankles 0.4698219578045296 1.5532856842637717 0.1203548987974829 1.0 0.490904009586989 33 O75844,O43318,Q12756,P49589,O60762,Q5JTV8,Q9UNE7 7 +Short long bone 0.5093976563168947 1.5518933970870177 0.1206877330896918 1.0 0.490904009586989 24 Q15427,Q96HY6,O94761,Q9NWH9 4 +Fine hair 0.5889442183530719 1.5506830808210688 0.1209776510867701 1.0 0.490904009586989 13 Q01968,P49589,Q96ST3,P36507,P18074 5 +Myoclonic spasms 0.764605132814794 1.5506753416111347 0.1209795066814856 1.0 0.490904009586989 5 P00846 1 +Hallux valgus 0.5610334507725916 1.5501047712738378 0.1211163710541822 1.0 0.490904009586989 15 Q15427,P31749 2 +Limb pain 0.6756179207568819 1.5469184232695126 0.1218829179429494 1.0 0.490904009586989 9 P20936,P36551,O95140,P00846 4 +Mottled pigmentation 0.8906708605079863 1.5401004144132944 0.1235358787933202 1.0 0.4915387616051949 4 O94761 1 +Natal tooth 0.6930548493850235 1.532202320476483 0.1254725161082253 1.0 0.4963965216961137 8 O75844,P14923 2 +Aplasia hypoplasia of the fibula 0.7394363021340672 1.5245518600375751 0.1273709124031197 1.0 0.5016473412302089 6 Q9NWH9 1 +Abnormal waist to hip ratio 0.7391035642455412 1.5231920255810083 0.127710670589618 1.0 0.5016473412302089 6 Q9Y6M1,P17096,P31751 3 +Type i diabetes mellitus 0.6271734269842947 1.5194863847198692 0.1286401125891907 1.0 0.5040728782983207 11 Q5JRA6,Q13217,Q13043,Q9UNE7 4 +Melanoma 0.5501635196912653 1.517127699430566 0.1292344460091246 1.0 0.5044658483745749 16 O94761 1 +Abnormal t wave 0.9007890910710206 1.516762452067456 0.1293266701847177 1.0 0.5044658483745749 3 P14923 1 +Sudden death 0.5206344493706971 1.515196196183238 0.1297227260944766 1.0 0.5052476521507289 20 P04899,P14923,P31749 3 +Abnormal cardiomyocyte morphology 0.900137215137812 1.514364636199231 0.1299333833150795 1.0 0.5056322358462785 3 P35609 1 +Scaling skin 0.6882247997838833 1.5110009411817602 0.1307882110776554 1.0 0.5074410846024356 8 O75844 1 +Generalized hyperkeratosis 0.8826652524133265 1.5107683989340095 0.1308474686945191 1.0 0.5074410846024356 4 O75844 1 +Increased serum serotonin 0.8985193210545315 1.5084127742748152 0.1314489156189275 1.0 0.5087939334843716 3 P51608,P46100 2 +Spina bifida 0.4744260719125279 1.5077896481916055 0.1316083723991918 1.0 0.5087939334843716 31 P21281,Q96ST3,O94761 3 +Pseudoarthrosis 0.898309191880059 1.507639684072315 0.1316467703061599 1.0 0.5087939334843716 3 O75844 1 +Abnormal activity of mitochondrial respiratory chain 0.4248615867904061 1.5053607848697916 0.1322313453972436 1.0 0.5098093447359608 49 Q9Y3D9,P52815,P51970,Q86Y39,Q9Y2R0,Q96EY7,Q9NX14,Q9Y584,Q9UBX3,Q5JPH6,P13073,O75489,Q70HW3,Q16795,O75306,Q8TB37,O43676,Q9H0R6,O75251 19 +Abnormal neural tube morphology 0.4385617704783989 1.5042877853586416 0.1325072827702356 1.0 0.5098093447359608 37 P21281,Q96ST3,O94761 3 +Scotoma 0.6014765566854926 1.4997387114461649 0.1336820987327955 1.0 0.5109777682527669 12 P00846 1 +Hypochromic anemia 0.5992811199522403 1.4885077215643945 0.1366170473386989 1.0 0.5165153304403697 12 Q9UER7,O75027,P46100 3 +Curly hair 0.5981413674206852 1.4826748006521362 0.1381608328893047 1.0 0.5201755358282322 12 Q14004,P14923,Q9UQ13,Q9Y5P4,Q96A33 5 +Dystrophic toenail 0.7471205271431314 1.4810833661806335 0.1385843597918801 1.0 0.52133566822624 5 O75844 1 +Bruxism 0.7045189270370815 1.4782549303149672 0.1393395561480948 1.0 0.5226657768260604 7 Q9Y5P4,Q96RL7 2 +Abnormality of the radial head 0.7278540019255804 1.4771626317322577 0.139632047947998 1.0 0.5226657768260604 6 O94761 1 +Ocular anterior segment dysgenesis 0.3687039076476233 1.470471115452813 0.1414342030774271 1.0 0.5270901778907434 82 O95202,P07954,Q01968,P61353,P42766,P31749,P62244,P39019,O94761,Q9NVI7,P18077,Q15800,P36507,Q71SY5,Q5SRE5,P62899 16 +Skeletal dysplasia 0.4412402552999649 1.4701762340798308 0.1415140296107728 1.0 0.5270901778907434 36 O43318,P31749,P51648,O94761,Q15427,Q96HY6,Q07864 7 +Adrenal hypoplasia 0.7236332989410148 1.4598673516441611 0.1443265336180801 1.0 0.5316396976578471 6 O75844 1 +Carpal synostosis 0.6765555152285286 1.4596869335085807 0.1443761346247007 1.0 0.5316396976578471 8 O94761 1 +Synostosis of carpals tarsals 0.6765555152285286 1.4596869335085807 0.1443761346247007 1.0 0.5316396976578471 8 O94761 1 +Slow decrease in visual acuity 0.6760054142515621 1.4572649789396546 0.1450432500161791 1.0 0.5332345743398021 8 P00846,O95140,P31749 3 +Abnormal caudate nucleus morphology 0.6551727536056767 1.4538390688639555 0.1459909289601491 1.0 0.5332345743398021 9 Q13057,P00846 2 +Segmental peripheral demyelination remyelination 0.8836528610475278 1.4536808739844902 0.1460348031979068 1.0 0.5332345743398021 3 P00846 1 +Ectopic anus 0.592084797580968 1.451652954759218 0.1465981265436899 1.0 0.5345684711254167 12 O94761 1 +Small basal ganglia 0.6745918853789472 1.4510404327749304 0.1467686017530298 1.0 0.5347585021937007 8 P22570,P00846 2 +Duplication of thumb phalanx 0.4994662997577617 1.4473978233869187 0.1477855350274359 1.0 0.5380298527429135 22 P62244,P61353,P42766,P18077,P62899 5 +Rhizomelia 0.6533072404661434 1.445325957194595 0.1483663501531806 1.0 0.5386357844359663 9 Q03164 1 +Reduced systolic function 0.8806811286049345 1.44273273292367 0.1490957746403305 1.0 0.5393232264411636 3 P14923 1 +Dilation of lateral ventricles 0.4972222344952182 1.4327361636615057 0.1519332505105395 1.0 0.5471656681062987 22 Q12756,Q08209,Q96RL7,Q71SY5,Q9NX14,P18583 6 +Spina bifida occulta 0.5286451098916298 1.4300234246114756 0.1527102961093969 1.0 0.5477677808951317 17 P21281,O94761 2 +Synostosis involving bones of the hand 0.6088562443463685 1.4294247692735775 0.1528821834392095 1.0 0.5477677808951317 11 O94761 1 +Neonatal death 0.5438430689027705 1.426899841060294 0.1536087666765291 1.0 0.5486200852526155 14 Q53EZ4,Q9NX14,Q9NVI7,P15924 4 +Facial hemangioma 0.8594993713009189 1.4257429476070036 0.1539425546492729 1.0 0.5487589449200194 4 O94761 1 +Epidermal acanthosis 0.6682680591323579 1.423174043491212 0.1546857081360038 1.0 0.5502913616995788 8 Q06136,P14923,P31749 3 +Papule 0.5202039676365514 1.420085233484263 0.1555828686787195 1.0 0.5511522555036736 18 O75844,P31749 2 +Talipes calcaneovalgus 0.8736468762948997 1.4168106028334675 0.1565383089149195 1.0 0.5525313122481299 3 P07196 1 +Clonus 0.4856840259485132 1.414630196997667 0.1571769502606965 1.0 0.5534882784706369 25 Q01968,O75027,Q12756,Q9BQT8,Q9UNE7 5 +Insulin resistant diabetes mellitus 0.6887453506872306 1.4112508074767445 0.1581706738085562 1.0 0.556120703709772 7 O75844,P40763,P31751 3 +Abnormal growth hormone level 0.4877412522132996 1.4066071073561217 0.1595439243907104 1.0 0.5566319034805793 24 Q03164,Q07864,P31749 3 +Sparse eyebrow 0.4455531076284544 1.406177906485614 0.159671302990445 1.0 0.5566319034805793 34 O75844,Q92643,P14923,O94761,Q9NVI7,Q71SY5,P15924 7 +Abnormal large intestine morphology 0.3821996338258728 1.402485838455214 0.160770216461862 1.0 0.5595992588402873 71 O75844,O43318,P62244,P61353,Q9H9Y6,P31749,P42766,O94761,P18077,Q9NX14,Q13043,P62899,Q07864 13 +Hypoplastic facial bones 0.5392153864110121 1.400982227833871 0.1612193876875489 1.0 0.5602993796710355 14 A5YKK6,O15160,Q9H9Y6,Q15427,P36507 5 +Hypochromic microcytic anemia 0.869050733831242 1.399868955698038 0.1615525639297832 1.0 0.5604199599576406 3 O75027 1 +Abnormality of the helix 0.4500372978050024 1.3984194980655236 0.1619871313787895 1.0 0.5604199599576406 33 O75844,P14923,O94761,P36507,P23786,P15924 6 +Proximal tubulopathy 0.5017872428108298 1.3966446567823 0.162520454301124 1.0 0.5607394222489338 20 O75489,Q9NX14,O43676,Q86Y39 4 +Abnormality of the proximal phalanx of the thumb 0.7072202166064951 1.3964230839193426 0.1625871277437147 1.0 0.5607394222489338 2 O60828 1 +Symphalangism of middle phalanx of finger 0.7072202166064951 1.3964230839193426 0.1625871277437147 1.0 0.5607394222489338 2 O60828 1 +Hydrocele testis 0.8489219303631241 1.386869527783687 0.1654815512142402 1.0 0.5636917610874986 4 Q9NVI7,P31749 2 +Pulmonary embolism 0.8487975543390545 1.3864123105871078 0.1656210395077213 1.0 0.5636917610874986 4 P31749 1 +Narrow nose 0.7231134171169125 1.3851881042658831 0.1659949571664469 1.0 0.5636917610874986 5 Q07864 1 +Intellectual disability borderline 0.7043321299638958 1.3830267334430848 0.1666566689518824 1.0 0.5636917610874986 2 Q7Z392 1 +Intermittent diarrhea 0.7223774678447746 1.3822435234967254 0.1668969404466527 1.0 0.5636917610874986 5 Q9UER7,P46100,Q8WX93 3 +Decreased activity of mitochondrial complex iv 0.5265332578975608 1.3809193846813648 0.1673037489768785 1.0 0.5636917610874986 16 P13073,Q70HW3,Q9Y3D9,Q9Y2R0,Q9Y584,Q5JPH6 6 +Mitochondrial inheritance 0.863255847822239 1.3785056341782245 0.1680472295261799 1.0 0.5640201824581196 3 P00846 1 +Pancreatitis 0.5128921331483203 1.376040190856289 0.168809190587432 1.0 0.5645228650305782 18 O75489,Q9NZ08,Q9UNE7 3 +Furrowed tongue 0.7025310710442854 1.3732239078782975 0.1696827494439026 1.0 0.5661939896510724 6 P31749 1 +Melena 0.8616829180209431 1.3727065582171991 0.1698435895697754 1.0 0.5663124263293324 3 Q9UER7,P46100 2 +Horizontal nystagmus 0.4879839030668145 1.3723030848223134 0.1699691057229058 1.0 0.5663129938466729 22 O14773,P00846 2 +Ventricular fibrillation 0.8418613658589278 1.3609113437206684 0.1735417082438539 1.0 0.5714733511995133 4 Q9NX14 1 +Neoplasm of the large intestine 0.4145341139104267 1.3592940311716086 0.1740534346965274 1.0 0.572131543781861 40 P62244,P61353,P31749,P42766,P18077,Q13043,P62899,Q07864 8 +Upper limb amyotrophy 0.553103254134703 1.3590792233082116 0.1741214857680519 1.0 0.572131543781861 13 Q9BQT8,P07196 2 +Prominent superficial blood vessels 0.5734870625106867 1.3561641527895305 0.1750469448434286 1.0 0.5744469754428204 12 O75844,P20936,P32322,P54886,Q13043 5 +Cavernous hemangioma 0.715770040379655 1.3557969056498949 0.1751637961310868 1.0 0.5744469754428204 5 P50570,P36507,P31749 3 +Reticular hyperpigmentation 0.6978339350180472 1.352887247470452 0.1760916540353205 1.0 0.5753598753499641 2 Q9H488 1 +Woolly hair 0.713727567014603 1.3476185554617717 0.1777810993967454 1.0 0.5778963176346683 5 P14923,Q96A33 2 +Abnormality of circulating leptin level 0.8382348024539332 1.3475766864928986 0.1777945731545349 1.0 0.5778963176346683 4 O75844,P31751 2 +Abnormal motor nerve conduction velocity 0.5245675019216992 1.3431292632494083 0.179230121478408 1.0 0.580890738048384 15 P04792,Q71SY5,Q9Y3E5,P07196 4 +Fibular hypoplasia 0.8361109155892661 1.339767067229328 0.1803210855468622 1.0 0.5831715565502673 4 Q9NWH9 1 +Arteriovenous malformation 0.6936724006560493 1.3367848688016255 0.1812928696776312 1.0 0.5851009724800188 6 P31749 1 +Tissue ischemia 0.5063104455399376 1.336347574417531 0.1814356933254772 1.0 0.5851009724800188 18 O75844,Q9NZ08 2 +Dysmetric saccades 0.6923156008369118 1.3312013837264118 0.1831227562385691 1.0 0.5878338047907435 6 O14773 1 +Aplasia hypoplasia of the eyebrow 0.4110560750291265 1.3308579541384458 0.1832357543118461 1.0 0.5878338047907435 41 O75844,Q92643,P14923,O94761,Q9NVI7,Q15427,P36507,Q71SY5,P15924 9 +Aplasia hypoplasia of the phalanges of the hand 0.4068081630036793 1.3281985657384976 0.1841125181103036 1.0 0.5881526451890252 48 O75844,P21281,O43318,Q03164,O94761,P51608,Q5JRA6 7 +Macrocytic anemia 0.4353582809265776 1.3245230959612524 0.1853293777848303 1.0 0.5901488756716494 34 P62244,P61353,P42766,P39019,P00374,P62263,P18077,O76024,Q6P4A7,P62899 10 +Cleft soft palate 0.3939858838473354 1.319012140588255 0.187165053721303 1.0 0.5942457573526683 58 Q15392,P21281,O43318,P62244,P61353,P42766,O94761,P18077,P62899 9 +Thrombocytosis 0.457216379897069 1.3167714664786347 0.1879152399194816 1.0 0.595572268601788 29 P21281,P62244,P61353,P42766,P39019,P62263,P62081,P18077,P08865,P62899,P35610 11 +Eruption failure 0.6877447862154996 1.312387831391879 0.1893893105531163 1.0 0.5975285649992875 6 O75844 1 +Overtubulated long bones 0.8437918989321087 1.306752039965031 0.1912969383355216 1.0 0.6022854128222208 3 O75844 1 +Polymicrogyria 0.3771577971502496 1.3061707065816908 0.1914945121777576 1.0 0.6024876086484044 68 Q15392,P21281,Q12756,P51608,O94761,Q96F86,O95721,Q08209,Q15427,Q71SY5,P23786 11 +Urticaria 0.6639476359617957 1.305627148880989 0.1916793832207823 1.0 0.6026495848235872 7 P51648,Q15427 2 +Facial telangiectasia 0.8256658123386522 1.3013617644086024 0.1931346548950041 1.0 0.6055394662148708 4 P46100,Q07864 2 +Ambiguous genitalia male 0.8421000848581153 1.300517184752323 0.1934237703090855 1.0 0.6059184964120619 3 Q15392 1 +Optic disc hypoplasia 0.8251668336421044 1.2995272986898738 0.1937630312705656 1.0 0.6059184964120619 4 Q96KP1,O95721 2 +Short lingual frenulum 0.8249607962674093 1.2987698234489575 0.194022933630956 1.0 0.6059184964120619 4 O75844 1 +Impaired collagen induced platelet aggregation 0.6855595667870003 1.2959849427347103 0.1949806724898994 1.0 0.6059184964120619 2 P27797 1 +Nonketotic hypoglycemia 0.7008124289044204 1.295878851210693 0.1950172265061018 1.0 0.6059184964120619 5 P31751 1 +Abnormal 3rd finger morphology 0.8406720225743652 1.2952547893218374 0.1952323498400201 1.0 0.6059184964120619 3 Q71SY5 1 +Abnormal atrial arrangement 0.6844765342960255 1.290967060908195 0.1967150996080544 1.0 0.6059184964120619 2 P57076 1 +Chronic bronchitis 0.6844765342960255 1.290967060908195 0.1967150996080544 1.0 0.6059184964120619 2 P57076 1 +Abnormal respiratory motile cilium physiology 0.6844765342960255 1.290967060908195 0.1967150996080544 1.0 0.6059184964120619 2 P57076 1 +Nasal congestion 0.6844765342960255 1.290967060908195 0.1967150996080544 1.0 0.6059184964120619 2 P57076 1 +Absent shortened dynein arms 0.6844765342960255 1.290967060908195 0.1967150996080544 1.0 0.6059184964120619 2 P57076 1 +Absent outer dynein arms 0.6844765342960255 1.290967060908195 0.1967150996080544 1.0 0.6059184964120619 2 P57076 1 +Wheezing 0.6844765342960255 1.290967060908195 0.1967150996080544 1.0 0.6059184964120619 2 P57076 1 +Respiratory insufficiency due to defective ciliary clearance 0.6844765342960255 1.290967060908195 0.1967150996080544 1.0 0.6059184964120619 2 P57076 1 +Abnormal respiratory motile cilium morphology 0.6844765342960255 1.290967060908195 0.1967150996080544 1.0 0.6059184964120619 2 P57076 1 +Abnormal shoulder physiology 0.822430773939727 1.2894689319909716 0.1972351104650871 1.0 0.6061148007226131 4 O94761 1 +Disproportionate short limb short stature 0.5150263681079592 1.2887540921719938 0.1974835906004961 1.0 0.6061148007226131 15 Q03164 1 +Brittle hair 0.514876826124964 1.287901514063639 0.1977802483841468 1.0 0.6061148007226131 15 O75844,Q9Y276,P49589,Q9NVI7,P36507,P18074 6 +Leukemia 0.3975714227875417 1.2769185078584984 0.2016310192636385 1.0 0.6095367238979585 52 P62244,P61353,P42766,O94761,Q13951,P18077,P46100,P62899 8 +Ragged red muscle fibers 0.5081591229731509 1.2746205473872223 0.2024435811657667 1.0 0.6107141755259126 16 Q9Y276,Q70HW3,Q9H2D1,P00846,Q5JPH6 5 +Acute myeloid leukemia 0.4291141953955282 1.2744894666960067 0.2024900033062897 1.0 0.6107141755259126 34 P62244,P61353,P42766,P39019,P62263,P62081,Q13951,P18077,P62899 9 +Late onset 0.6157154560787189 1.2733076707042543 0.2029088858222869 1.0 0.611569276948027 9 O76024,Q9Y6M1,P17096,P31751 4 +Abnormality of krebs cycle metabolism 0.81694312226753 1.2692989668688326 0.2043344547075447 1.0 0.6143695504846877 4 P00846 1 +Hypopituitarism 0.4427864720171646 1.2690325132599871 0.2044294681103786 1.0 0.6143695504846877 31 Q03164,Q07864,P31749 3 +Genu varum 0.6138298507717072 1.264665600168004 0.2059912263058183 1.0 0.617563610119235 9 O94761 1 +Delayed menarche 0.675257070019283 1.2609688769437086 0.2073200606290028 1.0 0.6182863940632898 6 O75844 1 +Leg muscle stiffness 0.8297373008854227 1.2549783252669098 0.209486628383301 1.0 0.621517161693931 3 P00846 1 +Papilloma 0.6287940228224648 1.248754955017286 0.211754713968346 1.0 0.6228731644753367 8 Q13043,P31749 2 +Abnormal renal tubule morphology 0.4777788631698536 1.2450521278191875 0.2131125895130958 1.0 0.6240069212055522 20 Q01968,Q9Y276,P22033,P00846,P23786 5 +Extrapyramidal dyskinesia 0.6736462093862778 1.2408277620271313 0.214669383142491 1.0 0.6254365464354074 2 P35610 1 +Abnormal 2nd finger morphology 0.6860787988861723 1.2368303250546646 0.2161500812971466 1.0 0.6269264555802848 5 Q71SY5 1 +Telecanthus 0.4072760451743867 1.236696649973796 0.2161997228762791 1.0 0.6269264555802848 37 O75844,P21281,O43318,Q03164,P10412,P36507,P46100,Q00839,Q86XL3,P29372 10 +Nuclear cataract 0.6859530629912158 1.2363264395039395 0.2163372470804021 1.0 0.6269264555802848 5 Q99797 1 +Wrist flexion contracture 0.6843312745569226 1.2298273170320049 0.2187617764543923 1.0 0.6302334791708316 5 O43318 1 +Impaired proprioception 0.4179282480260041 1.2277328791677893 0.2195472595599583 1.0 0.6309888795749947 35 P07196,Q13217,P00846,Q9UNE7,O14773 5 +Lethargy 0.3676576074814722 1.226704288288664 0.2199337553631877 1.0 0.631007234312617 70 P62244,P61353,P42766,Q8TB37,O75489,P39019,O43676,Q86Y39,P18077,P23786,Q9HCC0,Q9NX14,P62899 13 +Abnormal eyelid physiology 0.6237854289459982 1.2266008716374477 0.2199726414436413 1.0 0.631007234312617 8 P04350,Q96RL7,Q9H9Y6 3 +Long nose 0.6661217384234158 1.2233505127483033 0.2211973361114338 1.0 0.6325123826275053 6 O94761 1 +Hypersomnia 0.6685920577617291 1.2174603476929655 0.2234291143140623 1.0 0.63625754489682 2 O95551 1 +Elevated circulating growth hormone concentration 0.668592057761729 1.2174603476929655 0.2234291143140623 1.0 0.63625754489682 2 P10644 1 +Pituitary prolactin cell adenoma 0.668592057761729 1.2174603476929655 0.2234291143140623 1.0 0.63625754489682 2 P10644 1 +Abnormal globus pallidus morphology 0.6430000105155647 1.216289420129098 0.2238746903628115 1.0 0.63625754489682 7 P22033,Q13057 2 +Demyelinating peripheral neuropathy 0.5062808403987912 1.216081845188357 0.2239537456413682 1.0 0.63625754489682 14 Q13217,P00846 2 +Hypothermia 0.5827569843700294 1.2070918253933558 0.2273967826863132 1.0 0.6413464387617518 10 Q9H0U9,P00846 2 +Hypoketotic hypoglycemia 0.6408277589425037 1.2070268248852376 0.2274218135003485 1.0 0.6413464387617518 7 P55084,P23786,P31751 3 +Hemiparesis 0.5005919185495713 1.206447297822546 0.2276450683288788 1.0 0.6413464387617518 15 P31749 1 +Restless legs 0.816524709649765 1.2063724995681486 0.227673894704073 1.0 0.6413464387617518 3 P07196 1 +Fibrous tissue neoplasm 0.4907603820654845 1.2063213707319231 0.2276936006582226 1.0 0.6413464387617518 17 Q15392,P21281,P31749 3 +Ventricular preexcitation 0.6756516453352 1.1950532919920516 0.2320662093598344 1.0 0.6479396877189538 5 O75306,P00846 2 +Soft doughy skin 0.6635379061371802 1.1941178455182084 0.2324318734954482 1.0 0.6482266694150834 2 P18583 1 +Progressive gait ataxia 0.5796181171348678 1.1921672367460474 0.2331956772928243 1.0 0.649554913692343 10 P00846 1 +Underdeveloped nasal alae 0.4602966857290328 1.1908213030005403 0.2337237440275288 1.0 0.649967577373578 22 Q96ST3,O94761 2 +Pathologic fracture 0.49737396186198 1.1881025500988234 0.2347930098020605 1.0 0.651707463136302 15 O94761 1 +Osteolysis involving bones of the upper limbs 0.6362175378988637 1.1873727203512847 0.2350806353909567 1.0 0.651810217417757 7 O75844 1 +Abnormal neutrophil count 0.375967340932729 1.1849450968881317 0.2360391552950242 1.0 0.6527553380656358 61 P62244,P61353,P42766,Q9Y3C6,P39019,O94761,P18077,P22033,P26038,P40763,P46100,Q13043,P62899 13 +Venous malformation 0.8091976836535208 1.1794584102465568 0.2382156882000257 1.0 0.657405681918007 3 P31749 1 +Abnormal ureter physiology 0.3936214502655549 1.1755412287794664 0.2397782526717491 1.0 0.6597552652685521 41 P42695,O43318,Q8IZT6,O94761,P46100 5 +Abnormal blood glucose concentration 0.3516011161440396 1.172437413940563 0.2410214857206063 1.0 0.6598515923044553 78 O75844,Q9Y276,Q8TB37,O75489,Q16822,O43676,P14927,Q86Y39,P31751,P23786,Q9HCC0,P40763,O95470,Q9NX14 14 +Total anomalous pulmonary venous return 0.8070143899489597 1.171445367165329 0.2414198056837682 1.0 0.6598515923044553 3 Q15392 1 +Prenatal maternal abnormality 0.5373300570387141 1.1700588394911888 0.2419772910521254 1.0 0.6603598603066955 12 P57076,P22570 2 +Acantholysis 0.6692884525409354 1.1695740052564514 0.2421724433890175 1.0 0.6603598603066955 5 P14923 1 +Limitation of movement at ankles 0.7890968249543813 1.1671050562340473 0.2431679462053706 1.0 0.6603598603066955 4 O75844 1 +Osteolysis involving bones of the feet 0.7890659961649076 1.1669921307233435 0.243213547487902 1.0 0.6603598603066955 4 O75844 1 +Foot acroosteolysis 0.7890659961649076 1.1669921307233435 0.243213547487902 1.0 0.6603598603066955 4 O75844 1 +Muscle stiffness 0.4838741658625379 1.1656388668940587 0.2437604865314209 1.0 0.6611352281359357 17 Q15392,P23786,P00846,Q12756 4 +Hammertoe 0.517004162827357 1.1651998167347857 0.2439381198102268 1.0 0.6611352281359357 13 O00764,P07196 2 +Focal t2 hyperintense brainstem lesion 0.4931913439687094 1.1642665472738916 0.2443160089751228 1.0 0.6617624271880126 15 Q8TB37,O75489,O43676,Q86Y39,Q9NX14 5 +Short nose 0.3355075502690658 1.162269788763738 0.2451258943218992 1.0 0.6619717815578845 86 Q15392,O75844,Q03164,Q96ST3,O94761,Q9NVI7,P46100,P36507,Q9NX62 9 +Entropion 0.6082504130638761 1.15792319964346 0.2468953790832024 1.0 0.6663520446224067 8 O75844,P18074,P36543 3 +Cutaneous photosensitivity 0.452722929961048 1.1547088418901892 0.2482096774929654 1.0 0.6683023378505469 23 O94761 1 +Abnormal soft palate morphology 0.3650182041316307 1.1537967903192885 0.2485834903958761 1.0 0.6685120295289098 66 Q15392,P21281,O43318,P62244,P61353,P42766,O94761,P18077,Q15427,P62899 10 +Hypoplasia of the frontal lobes 0.589535174403153 1.1533593710067715 0.2487629104479121 1.0 0.6685965671645847 9 P42695,P22570,Q8IZT6 3 +Mild short stature 0.6530685920577577 1.1458623304787083 0.2518521198240862 1.0 0.6723148603145433 2 P10644 1 +Abnormally ossified vertebrae 0.6530685920577578 1.1458623304787083 0.2518521198240862 1.0 0.6723148603145433 2 O75369 1 +Giant platelets 0.6530685920577577 1.1458623304787083 0.2518521198240862 1.0 0.6723148603145433 2 P35579 1 +Absent or minimally ossified vertebral bodies 0.6530685920577578 1.1458623304787083 0.2518521198240862 1.0 0.6723148603145433 2 O75369 1 +Poor coordination 0.6472664682884234 1.1457662228898096 0.2518918945526844 1.0 0.6723148603145433 6 P49589,Q9NQ48 2 +Peripheral demyelination 0.5127032160486087 1.1421175201319589 0.2534051738429297 1.0 0.6744845989319351 13 P00846 1 +Right bundle branch block 0.587013793518165 1.1418208426411802 0.2535284969135123 1.0 0.6744845989319351 9 P04899 1 +Erythema 0.4613267498365619 1.141137197788613 0.2538128338803713 1.0 0.674544931453834 20 Q06136,P51648,O94761,Q9NX14,P15924 5 +Ovarian cyst 0.4915147180669564 1.1331741101087252 0.2571411441720188 1.0 0.6801895136821904 14 P31749 1 +Recurrent sinusitis 0.7792959801530691 1.1312380175729924 0.2579549245062853 1.0 0.6811457328576255 4 Q13432 1 +Endocarditis 0.6594290857508486 1.1301324513298028 0.2584204174936235 1.0 0.68197631205385 5 Q9NZ08,P10644 2 +Aplasia hypoplasia involving bones of the feet 0.3810709586699853 1.1288291022994328 0.2589699333680459 1.0 0.6830275300390144 53 O95202,P21281,O43318,Q03164,O94761,Q9Y5P4,Q15427,Q96A33,P51608,Q9NX62 10 +Visual field defect 0.3879932517006317 1.1255254568031756 0.2603664360336708 1.0 0.6851109831101484 41 P22570,P00846 2 +Abnormality of the internal auditory canal 0.777528197322133 1.124776454304612 0.2606837744096089 1.0 0.6851479306472443 4 P31749,Q9H9Y6 2 +Narrow internal auditory canal 0.777528197322133 1.124776454304612 0.2606837744096089 1.0 0.6851479306472443 4 P31749,Q9H9Y6 2 +Transposition of the great arteries 0.6415119589536202 1.1221209087759312 0.261811034917675 1.0 0.6861149975394754 6 O75844 1 +Skin plaque 0.6206302387097706 1.1209908572693708 0.2622917541357243 1.0 0.6861457973206033 7 Q06136 1 +Sarcoma 0.378021505476788 1.1207161406247144 0.2624087095220355 1.0 0.6861457973206033 55 Q15392,P21281,Q96JJ3,P62244,P61353,P31749,P42766,P39019,O94761,P18077,P62899 11 +Short chin 0.5459447522452954 1.1186946334060526 0.2632704354522506 1.0 0.6861457973206033 11 O94761 1 +Sensorimotor neuropathy 0.4330455900101975 1.1181724443628944 0.2634933506753534 1.0 0.6861457973206033 28 Q13217,Q8N2K0,P00846 3 +Ureteral duplication 0.7753897367742539 1.1169635125030983 0.2640099264870927 1.0 0.6865759460333094 4 O75844 1 +Paraganglioma 0.5987431365594323 1.1159517976308222 0.2644427681010572 1.0 0.6865759460333094 8 Q9UER7,P46100 2 +Diplopia 0.4846924698711035 1.1158766184136313 0.2644749515146234 1.0 0.6865759460333094 15 P18074,Q14671,Q04637,O14773 4 +Focal t2 hyperintense basal ganglia lesion 0.4697492890741848 1.1156876574417436 0.2645558555944958 1.0 0.6865759460333094 18 P00846 1 +Abnormal corneal epithelium morphology 0.4846533168947237 1.1156538699060767 0.2645703236042478 1.0 0.6865759460333094 15 O75844,Q9NZ08 2 +Biliary atresia 0.6458483754512596 1.1126749799677345 0.2658480449347236 1.0 0.6888155571135468 2 Q10713 1 +Congenital malformation of the right heart 0.6391010007444897 1.1122208781339888 0.2660431932632003 1.0 0.6888155571135468 6 P21281,P57076,P01889 3 +Abnormality of peripheral nerves 0.3866055638443276 1.1116291590712624 0.2662976299406268 1.0 0.689079434176261 38 Q12756,P07196,O95721,P04792,Q96RL7,Q71SY5,Q9Y3E5,Q8N2K0 8 +High hypermetropia 0.5795083570176702 1.1075015223850866 0.2680771544534635 1.0 0.6920986193261417 9 Q71SY5,O15294 2 +Dry hair 0.7888890063822454 1.105070568973632 0.2691290121396164 1.0 0.6928346876619867 3 Q9Y276 1 +Lower eyelid coloboma 0.771803573501607 1.1038704369947774 0.2696493445856929 1.0 0.6936252165823572 4 Q15427,Q9H9Y6 2 +Paroxysmal involuntary eye movements 0.4785534573405243 1.1033357932319323 0.2698813682559369 1.0 0.6936252165823572 16 Q8TB37,O75489,O43676,Q86Y39,Q9NX14 5 +Lower limb hyperreflexia 0.478314077516406 1.1019537986104355 0.270481757991754 1.0 0.694733702448405 16 P13073,Q12756,P54886,Q5T440,O60762,P51608,P07384 7 +Increased serum pyruvate 0.4242301557259058 1.101098072571943 0.270853975817841 1.0 0.6948511000865384 30 Q9Y276,O75489,O43676,Q70HW3,Q86Y39,P51608,Q9NX14 7 +Breathing dysregulation 0.6425992779783354 1.0977694722557976 0.272305164968035 1.0 0.6966448104901372 2 Q10713 1 +Upper airway obstruction 0.6502571764588312 1.0934973261045358 0.2741755023627497 1.0 0.7002402033210305 5 O75844 1 +Cardiac conduction abnormality 0.4353826136187766 1.0904606912722326 0.2755102598032044 1.0 0.7012175768027732 26 P35609,P04899,P00846 3 +Abnormal nasal mucosa morphology 0.784673497095319 1.0896782119611317 0.2758549170480748 1.0 0.7013556671053134 3 Q13432 1 +Fragile skin 0.5924620628158266 1.0882621117821858 0.2764794116437938 1.0 0.7017606639363262 8 P14923,P36551,Q15149,P15924 4 +Chronic noninfectious lymphadenopathy 0.7831762729538355 1.0842159964973672 0.278269040688138 1.0 0.7035348835699546 3 P46100 1 +Joint stiffness 0.3790689135351973 1.083866119166604 0.2784241637501281 1.0 0.7035348835699546 50 O75844,Q01968,Q8NBU5,P31749,P51648,O94761,O76024,Q15427,P46100,P51608,O95140 11 +Hyperglycemia 0.6309786173736397 1.0789027160092408 0.2806310979616646 1.0 0.7068421133630449 6 O75844 1 +Airway obstruction 0.4781611343839758 1.0787474969703663 0.2807003057992219 1.0 0.7068421133630449 15 O75844,P09601 2 +Abnormality of the phalanges of the toes 0.5185873029112336 1.0737753247776918 0.2829233917614817 1.0 0.7073867647915741 12 P21281,Q71SY5,O75844 3 +Progressive inability to walk 0.4563488572878466 1.0703838056278463 0.284446585645282 1.0 0.7084507574120089 19 Q96RL7,O75190,P00846 3 +Rod cone dystrophy 0.3928606078342299 1.0660594363110274 0.286396774757681 1.0 0.7109563892061553 36 P57076,Q13868,P22570,Q9Y276,Q9NQ48,Q15067,Q8TC12,P00846,Q8N2K0 9 +Bilateral external ear deformity 0.7611607150176407 1.065088185309639 0.2868360252343471 1.0 0.7116557726572106 4 P14923 1 +Glucose intolerance 0.3314294517565483 1.0639924357720698 0.2873321262342911 1.0 0.7118116334359149 96 P00846,O75844,Q9Y6M1,Q86Y39,Q13217,Q5JRA6,Q9NX14,P17096,Q96JJ3,Q06136,O75489,P49589,P31751,P40763,Q13043,P61457,O43676,Q9Y3E5,Q9UNE7 19 +Abnormal dermoepidermal junction morphology 0.7768147345611998 1.0610370545191894 0.2886730618145696 1.0 0.7134709481828367 3 P14923,P15924 2 +Female reproductive system neoplasm 0.4544126181330349 1.0584836874050456 0.2898349838766287 1.0 0.71438868366318 19 Q07864,P31749 2 +Increased circulating acth level 0.7585932746358715 1.0557510903153249 0.2910819488391625 1.0 0.7151620580655836 4 P46100 1 +Abnormal renal pelvis morphology 0.377786053142557 1.0532940012783252 0.2922062673755827 1.0 0.7171037023372531 47 P21281,O43318,O94761,Q08209,O76024,P23786,P36507,P46100,Q71SY5,Q5JRA6,Q07864 11 +Aplasia hypoplasia of fingers 0.3364005423770637 1.052023606852014 0.2927887189680171 1.0 0.7177533544750415 81 O95202,O75844,P21281,O43318,Q03164,P61353,P42766,P62244,Q96ST3,O94761,P18077,Q15427,P51608,P62899 14 +Contractures of the joints of the lower limbs 0.3781050740867021 1.051468316960801 0.2930435534307021 1.0 0.7179884893708851 46 O43318,P14923,Q9Y3E5,O60762,P40763,Q5JTV8,P23786,Q8N2K0,P15924 9 +Dysplastic corpus callosum 0.5491961104956047 1.047861904112863 0.2947022363872285 1.0 0.7197106508094585 10 Q96ST3,Q9NVI7 2 +Bloody diarrhea 0.6385733762542483 1.0469367501285187 0.2951287508039728 1.0 0.720063819947384 5 Q9UER7,P46100 2 +Camptodactyly of toe 0.6222086196675058 1.0430002152158724 0.296948193083673 1.0 0.7220731627298357 6 P14923,Q8IWS0,P15924 3 +Aplasia hypoplasia involving bones of the lower limbs 0.3486347694486045 1.0415221298379902 0.2976332879673546 1.0 0.7221303178725312 72 O95202,P21281,O43318,Q03164,O94761,Q9NWH9,Q9Y5P4,Q15427,Q96A33,Q96HY6,P51608,Q9NX62 12 +Abnormality of subcutaneous fat tissue 0.4715951011397986 1.041491837246017 0.2976473396681607 1.0 0.7221303178725312 15 O75844 1 +Disproportionate short stature 0.4516437185093253 1.0414802234393885 0.2976527270347311 1.0 0.7221303178725312 19 Q15392,Q03164 2 +Recurrent lower respiratory tract infections 0.4306824347986834 1.039044704769808 0.2987839455800307 1.0 0.7228255647273021 25 Q71SY5,Q13432,P13051 3 +Abnormal granulocyte count 0.3542208384336593 1.0385855471413254 0.298997530345829 1.0 0.7228255647273021 66 P62244,P61353,P42766,Q9Y3C6,P39019,O94761,P18077,P26038,P46100,Q13043,P62899 11 +Sideroblastic anemia 0.5472224080423991 1.0385352010772608 0.2990209558480314 1.0 0.7228255647273021 10 O76024,Q9Y606,O75027 3 +Congenital contracture 0.4040516943766158 1.0381006446895595 0.2992232013479974 1.0 0.7228255647273021 33 Q15392,O75844,Q8NBU5,Q12756,Q53EZ4,Q08209,Q99986,P40763,Q96A33,P18074 10 +Cerebral hemorrhage 0.5293905118447819 1.037202496428395 0.299641494879765 1.0 0.7231732232194328 11 P07954,P23786,P31749 3 +Slanting of the palpebral fissure 0.2994996174905429 1.0352726629314473 0.3005415927527752 1.0 0.7245714600090921 171 O95202,Q03164,Q9H9Y6,O94761,Q9NVI7,Q9Y5P4,Q08209,P36507,Q71SY5,O75844,Q15392,Q14004,Q96ST3,Q96KP1,P21281,O43318,Q01968,Q8IZT6,P31749,Q8NC96,P42695,Q15427,P46100,P51608 24 +Acute leukemia 0.377347408650716 1.034599482575736 0.3008559957497212 1.0 0.7246390898354609 43 P62244,P61353,P42766,Q13951,P18077,P46100,P62899 7 +Abnormal mean corpuscular volume 0.4324477607760745 1.0345257968719026 0.3008904233137062 1.0 0.7246390898354609 24 P62244,P61353,P42766,P39019,P18077,P62899 6 +Abnormality of circulating adrenocorticotropin level 0.5628583281536986 1.0315760098385482 0.3022707836287095 1.0 0.7256547367231436 9 P46100,P31749 2 +Lumbar hyperlordosis 0.4696443076358841 1.0304395379871012 0.302803721051188 1.0 0.7256547367231436 15 Q96HY6,Q15149,P18583,O95140 4 +Abnormality of the pulmonary veins 0.5992614297902862 1.030304268040716 0.3028671961638751 1.0 0.7256547367231436 7 Q15392,P62244 2 +Abnormality of the metopic suture 0.4916644018793259 1.0295112029370577 0.3032395181348595 1.0 0.7256547367231436 13 Q00839,P18074,P40763,Q5SRE5 4 +Gingival fibromatosis 0.7502504576261123 1.0254669276978938 0.3051429226934492 1.0 0.7278963699730747 4 Q15392,P21281 2 +Abnormal lateral ventricle morphology 0.4169271971655534 1.0237239827182956 0.3059656643186739 1.0 0.7290890671897514 29 Q12756,Q08209,Q96RL7,P36507,Q71SY5,Q9NX14,P18583 7 +Multiple cafe au lait spots 0.5439436547948878 1.0230551873387828 0.3062817532745752 1.0 0.72931008481821 10 P31749 1 +Skin erosion 0.5772342259858233 1.021314042711921 0.3071056753583285 1.0 0.7300199687785817 8 O75844 1 +Acute coronary syndrome 0.4642714537052712 1.0210576611186897 0.3072271208226382 1.0 0.7300199687785817 16 O75844 1 +Abnormal blood gas level 0.7656600531613802 1.020521285506305 0.307481299572333 1.0 0.7300199687785817 3 Q9Y3E5 1 +Distal upper limb amyotrophy 0.525956135357874 1.0203468213048548 0.3075640050131811 1.0 0.7300199687785817 11 Q9BQT8 1 +Abnormal brainstem morphology 0.3428291834092014 1.0185970718331034 0.3083942950030227 1.0 0.7314044224796098 75 Q96KP1,Q13057,P07954,Q8TB37,Q12756,P31749,Q9Y3C6,O75489,O43676,Q86Y39,O60762,Q13217,Q99986,Q9NX14,Q9UNE7 15 +Polyneuropathy 0.4649861792257758 1.004084170528324 0.3153380446284126 1.0 0.7422922905529373 15 P00846 1 +Pain in head and neck region 0.6277266258456837 1.003852781501687 0.31544957898664 1.0 0.7422922905529373 5 P31749 1 +Abnormality of the wrist 0.4195730133603307 1.0018994766742384 0.3163921454014335 1.0 0.7433487846716988 27 O75844,O43318,Q01968,P31749,O94761 5 +Short ribs 0.5726992936368729 1.0014399273380303 0.3166141690401238 1.0 0.7434837919559665 8 Q15427 1 +Hodgkin lymphoma 0.5719546686350796 0.9981799156890616 0.3181921236793672 1.0 0.7445207205770816 8 P40763,Q07864 2 +Loss of ability to walk 0.4857784878576108 0.9981445366130768 0.318209276545893 1.0 0.7445207205770816 13 P00846,O75190 2 +Neoplasm of the skin 0.3734086847556666 0.9960374140251724 0.3192319668970749 1.0 0.7453695227085191 40 P20936,Q01968,P31749,Q06136,O94761 5 +Upper limb muscle weakness 0.4262820525549275 0.9933265771687624 0.3205508297605393 1.0 0.7465661070859558 24 P31749,P00846 2 +Saccadic smooth pursuit 0.7398550586776783 0.987867431376086 0.3232175777296531 1.0 0.7498559402349388 4 O14773 1 +Nausea and vomiting 0.3231277494187567 0.987807605443161 0.3232468820920986 1.0 0.7498559402349388 123 P31749,O75489,O94761,Q9NZ08,O43676,Q15165,Q9NWH9,Q86Y39,Q9HCC0,P00846,Q9NX14 11 +Cortical cataract 0.755874645548401 0.9851325866645342 0.3245589486436566 1.0 0.7504387563828253 3 Q01968 1 +Abnormality of the mitochondrion 0.321398481639488 0.983181637670922 0.3255180504501109 1.0 0.751118770139735 86 P13073,O75306,P22570,P51970,Q8TB37,Q9UBX3,O75489,O43676,Q70HW3,Q86Y39,Q9Y3D9,P23786,Q9Y2R0,P00846,Q9NX14,Q9Y584,Q5JPH6 17 +Syncope 0.5676929556016036 0.9795409436961908 0.3273127685306485 1.0 0.7543212740546164 8 P14923,P31749 2 +Teratoma 0.6166064981949415 0.9793505100500092 0.3274068212530108 1.0 0.7543212740546164 2 O95999 1 +Abnormal glucose homeostasis 0.292241728823466 0.9765358024486984 0.3287990148201181 1.0 0.7559867424719051 159 Q9Y276,Q16822,P14927,Q9HCC0,P00846,O75844,Q9Y6M1,Q86Y39,Q13217,Q9NX14,Q5JRA6,P17096,Q96JJ3,Q06136,O75489,P49589,P31751,P40763,P23786,Q13043,O95140,Q8TB37,P61457,O43676,O95470,Q9Y3E5,Q9UNE7 27 +Short palpebral fissure 0.4234863427367397 0.9746916491401404 0.3297132365266317 1.0 0.7573179474465288 24 Q03164 1 +Nemaline bodies 0.7359008030676266 0.9736093672858916 0.3302505334962942 1.0 0.7577815694953058 4 O43676 1 +Hydrocephalus 0.3477040543191394 0.9695381859199844 0.3322767373634061 1.0 0.7600241067573258 66 O95202,Q15392,P20936,P57076,Q12756,P31749,P32322,Q10713,O94761,Q14738,Q9NX14,Q9UQ13,P23786,Q15427,P36507,Q00839,P18074,O95140 18 +Abnormality of the testis size 0.4202583473971538 0.9684461272857904 0.3328216119183329 1.0 0.7600241067573258 25 O43318,P31749,Q8IWS0,Q9H7N4,P46100,P51608,O15294 7 +Allergic rhinitis 0.614079422382667 0.9679320755481076 0.3330782937980312 1.0 0.7600241067573258 2 Q6P1M0 1 +Unusual skin infection 0.614079422382667 0.9679320755481076 0.3330782937980312 1.0 0.7600241067573258 2 Q03426 1 +Molluscum contagiosum 0.614079422382667 0.9679320755481076 0.3330782937980312 1.0 0.7600241067573258 2 Q03426 1 +Progressive visual loss 0.4272459559312377 0.9661321376597616 0.3339780650151558 1.0 0.7616925278841363 21 O14773,P00846 2 +Aplasia hypoplasia of the sternum 0.750090285301551 0.9642901621094112 0.3349004717764705 1.0 0.7617933100432462 3 Q9Y619,P98175 2 +Abnormal mitochondria in muscle tissue 0.4442386834883005 0.9626514967377756 0.3357224451575997 1.0 0.7617933100432462 18 Q8TB37,O75489,O43676,Q86Y39,Q9NX14 5 +Diastema 0.6020600699260553 0.9609026946252543 0.3366010958022436 1.0 0.7617933100432462 6 Q9BSJ2,Q8TC12,P46100 3 +Soft skin 0.5825522221481955 0.9598179613535012 0.3371468409295883 1.0 0.7617933100432462 7 P21281 1 +Phimosis 0.6122743682310425 0.9597881123162464 0.3371618664527487 1.0 0.7617933100432462 2 O60828 1 +Abnormal rib cage morphology 0.3473147764289306 0.9580714829732446 0.3380267141525914 1.0 0.762004413844702 65 O95202,O75844,P21281,O43318,Q03164,Q01968,P31749,O94761,Q15427,Q96HY6 10 +Basal ganglia gliosis 0.5618586665614042 0.954081025695025 0.34004262982204 1.0 0.7638023339254013 8 Q99986,P00846 2 +Abnormal renal insterstitial morphology 0.5291346363555014 0.95339098670845 0.3403920064694055 1.0 0.7638023339254013 10 P23786,Q9Y276 2 +Distal amyotrophy 0.3626383006959826 0.952960610154232 0.3406100287208127 1.0 0.7638023339254013 53 Q13057,Q9BQT8,Q12756,P07196,Q9NVI7,P04792,Q96RL7,P35609,Q71SY5,Q9Y3E5,Q9UNE7,Q8N2K0 12 +Increased intracranial pressure 0.4472688637269784 0.9505391729824674 0.3418383592238863 1.0 0.7638109332213245 17 P31749 1 +Sprengel anomaly 0.403645715631988 0.94981125482062 0.34220816605953 1.0 0.7642477260518732 30 O43318,P62244,P61353,P42766,P18077,Q15427,P62899 7 +Abnormal peripheral myelination 0.4172866609599197 0.9484022113572952 0.3429247340979007 1.0 0.7651031845206495 25 Q96RL7,Q12756,P07196,P00846 4 +Poor appetite 0.5276431156548084 0.9464014597251128 0.3439438611578871 1.0 0.7658641521494992 10 Q9UER7,Q70HW3,P46100,Q8WX93 4 +Abnormal eyelash morphology 0.3420580067719966 0.9457138070535168 0.3442945782857769 1.0 0.7658901549459085 70 O75844,P21281,Q03164,Q9H9Y6,P14923,O94761,Q15427,Q9NX14,P15924 9 +Anorexia 0.4165248793724148 0.9432707853101132 0.3455424150509611 1.0 0.7674852855820694 25 P01889,P42771,Q8WX93,P27797,Q9NZ08,P22033,P40763,P46100,P51608,Q9UER7,P10644,P35610 12 +Broad columella 0.7270149973919748 0.941668631535418 0.3463623197985019 1.0 0.7684397459898741 4 Q8TC12,Q13868 2 +Leiomyosarcoma 0.5588817334868439 0.94111782368547 0.3466444825563894 1.0 0.7684397459898741 8 P31749 1 +Delayed ability to roll over 0.7264166282158563 0.9395229933559958 0.3474622925539474 1.0 0.7687730841129944 4 P51608,P51970 2 +Impaired vibratory sensation 0.4132917253858332 0.9385078596163308 0.3479834797625276 1.0 0.7689887055260569 26 Q96RL7,O14773,P07196,P00846 4 +Limited wrist movement 0.5963066307342708 0.9375852885320454 0.3484575746018372 1.0 0.7694678993407139 6 O75844 1 +Abnormal pancreas morphology 0.4494836687844285 0.9363959800690854 0.3490693469354515 1.0 0.7702183947651706 16 O94761,Q9Y3E5 2 +Abnormal vascular physiology 0.3652552782037846 0.935035864011803 0.349769817122759 1.0 0.7702183947651706 46 O75844,Q71SY5,Q9NZ08,P31749 4 +Abnormality of the ureter 0.357751375565881 0.9348591730003064 0.3498608797722258 1.0 0.7702183947651706 56 O75844,P42695,O43318,Q8IZT6,Q53EZ4,O94761,Q08209,P46100,P23786 9 +Abnormality of the choanae 0.3946377453243769 0.9346071662534936 0.3499907845181265 1.0 0.7702183947651706 32 O94761 1 +Dolichocephaly 0.4094633492741972 0.9315498966014556 0.3515691867206592 1.0 0.7723648825009553 27 P21281,Q03164,P46100,P31749 4 +Abnormal anatomic location of the heart 0.5244630952754625 0.9315181753067002 0.3515855873388958 1.0 0.7723648825009553 10 O75844,Q10713,P57076,O60828 4 +Delayed fine motor development 0.5947471442409571 0.9312764002557196 0.3517106063663875 1.0 0.7723648825009553 6 P22570 1 +Sudden loss of visual acuity 0.6050541516245441 0.9273189476382472 0.3537609594511699 1.0 0.773455623423643 2 O00170 1 +Deviation of the 2nd finger 0.7228556029677707 0.92676833565875 0.3540468285582367 1.0 0.773455623423643 4 Q71SY5 1 +Abnormality of the ribs 0.3598485854412963 0.9265912452158316 0.354138802151783 1.0 0.773455623423643 53 O95202,O75844,P21281,O43318,Q03164,Q01968,O94761,Q15427,Q96HY6 9 +Onion bulb formation 0.6081288455076089 0.9264716874691526 0.3542009041309246 1.0 0.773455623423643 5 P07196,O95140 2 +Short face 0.7394056055163729 0.9259588366373316 0.3544673727052512 1.0 0.7735274237048495 3 Q9H9Y6 1 +Abnormal corpus striatum morphology 0.4471540880808886 0.9231251815085798 0.3559419731655588 1.0 0.7739548212955664 16 Q13057,P00846 2 +Atrophy degeneration involving the caudate nucleus 0.7208909892943473 0.9197425184749336 0.3577073279557987 1.0 0.774004649283668 4 P00846 1 +Oligohydramnios 0.4125941152896991 0.9168399802898262 0.3592264989285891 1.0 0.7754349365309918 25 Q06265,P14923,Q9Y5P4,P23786,P15924 5 +Decreased testicular size 0.430192757805367 0.9105262108078848 0.3625450652337769 1.0 0.780932524696217 19 O43318,Q8IWS0,O15294,Q9H7N4,P46100,P18074 6 +Gait ataxia 0.3541021910368851 0.9103507789477662 0.3626375468819529 1.0 0.780932524696217 57 P22570,P07196,Q13217,P00846,Q9UNE7,O14773 6 +Focal emotional seizure 0.5353949509930331 0.9073719558836576 0.3642101344072652 1.0 0.781670644369315 9 Q08209 1 +Focal non motor seizure 0.5353949509930331 0.9073719558836576 0.3642101344072652 1.0 0.781670644369315 9 Q08209 1 +Oromandibular dystonia 0.7169737271789063 0.9057577827220094 0.3650640709005857 1.0 0.7817524942141568 4 Q13057 1 +Increased serum iron 0.731626524909939 0.8982033036502876 0.3690771724488051 1.0 0.78706576855008 3 Q9Y276 1 +Supernumerary tooth 0.586519191839622 0.8980780327969302 0.3691439494372774 1.0 0.78706576855008 6 O94761 1 +Widow s peak 0.714493339540335 0.8969199212562795 0.3697616491297877 1.0 0.7873250210211924 4 P21281 1 +Neoplasm of the peripheral nervous system 0.442328253656751 0.8957029878275368 0.3704114142303516 1.0 0.7879090251849005 16 Q9UER7,P46100,P31749 3 +Deep philtrum 0.4453467204522591 0.893680421145215 0.3714929038085806 1.0 0.7879835396277779 15 P21281,O43318,Q01968,P37837,Q9UQ13 5 +Abnormal sensory nerve conduction velocity 0.7124354754983118 0.8895980259468899 0.3736817665813383 1.0 0.791366385262398 4 Q9Y3E5,Q12756 2 +Aplasia hypoplasia affecting the fundus 0.4123761952616618 0.8889497386926605 0.3740300924746171 1.0 0.791366385262398 23 Q96KP1,P07196,Q9NVI7,O95721,P36507,Q00839,Q16851 7 +Adrenal hyperplasia 0.712208199551222 0.8887899702167354 0.3741159672023357 1.0 0.791366385262398 4 P17612,P21281 2 +Abnormality of the temporomandibular joint 0.7111903079622508 0.8851724319979741 0.3760636384947888 1.0 0.792412014867693 4 O75844 1 +Prominent metopic ridge 0.4980207588813762 0.8842480455189416 0.376562327561075 1.0 0.792412014867693 11 P18074,P40763,Q5SRE5 3 +Papillary renal cell carcinoma 0.7106644515658984 0.8833045105063541 0.3770717674462522 1.0 0.7927396663950187 4 Q9NWH9 1 +Abnormality of dental eruption 0.357643945425491 0.8792662107048702 0.3792569520555688 1.0 0.7942456481475708 49 O75844,P21281,Q96JJ3,O43318,Q01968,P14923,O94761,P51608,Q5JRA6,P15924 10 +Oculomotor apraxia 0.4135718711662799 0.8790583363715763 0.3793696463986844 1.0 0.7942456481475708 21 O14773 1 +Exaggerated cupid s bow 0.5958678557230372 0.878450012153818 0.3796995538574599 1.0 0.7942456481475708 5 Q96KP1 1 +Glaucoma 0.3218358614391353 0.877913029828005 0.3799909175920968 1.0 0.7942456481475708 81 Q01968,P61353,P42766,Q06136,P31749,P62244,O94761,P18077,P62899,Q9NX14,Q9UNE7 11 +Equinovarus deformity 0.709032534894595 0.8775118558619107 0.3802086821007855 1.0 0.7942456481475708 4 Q96RL7,P21281 2 +Pulmonary carcinoid tumor 0.7255991753579919 0.876794965323378 0.3805980142185681 1.0 0.7942456481475708 3 P46100 1 +Abnormality of thalamus morphology 0.4422517630022516 0.8764150985219005 0.3808044132051889 1.0 0.7942606370536976 15 Q96KP1,P31749 2 +Babinski sign 0.3301927634552067 0.875811358195499 0.3811325943188173 1.0 0.7942606370536976 75 O95140,O75027,Q12756,Q15067,P07196,Q8TD30,Q13217,P00846,P51608,Q9UNE7,Q8N2K0,O14773 12 +Hip dislocation 0.3530776662913544 0.8711203367513256 0.3836884510611007 1.0 0.7977470878481606 54 O75844,O43318,Q01968,P31749,O94761,Q15427,Q96A33,Q9Y3E5 8 +Abnormal circulating acetylcarnitine concentration 0.5796589289173864 0.8705216223845983 0.3840154080692484 1.0 0.7980596198973616 6 P55084,P23786 2 +Narrow vertebral interpedicular distance 0.7229350210094305 0.8673610191082317 0.385744233014913 1.0 0.7998129622585484 3 Q96HY6 1 +Vertebral arch anomaly 0.7229350210094305 0.8673610191082317 0.385744233014913 1.0 0.7998129622585484 3 Q96HY6 1 +Fragile nails 0.5602009187690192 0.866424720848767 0.3862572921405904 1.0 0.800142341078032 7 Q96ST3,Q10567,P15924 3 +Areflexia of lower limbs 0.427822568990805 0.8652903971866414 0.3868794201270493 1.0 0.800955075373397 18 Q15067,P07196,P04792,Q96RL7,Q13217 5 +Renal hypoplasia aplasia 0.3354329117585857 0.8646665697405533 0.3872218231785318 1.0 0.800955075373397 69 Q53EZ4,P18077,P62899,Q15392,O60828,P57678,P54886,P62244,Q8IZT6,P39019,Q9Y2W2,P42695,O75306,P61353,P42766,Q15427,P46100,Q86XL3,P18583 19 +Sagittal craniosynostosis 0.5781753693220677 0.8645785448058725 0.3872701527049549 1.0 0.800955075373397 6 O94761 1 +Retinal pigment epithelial atrophy 0.7040501469035368 0.8598664072981576 0.3898626879064952 1.0 0.8027820773173124 4 P51648 1 +Decreased number of peripheral myelinated nerve fibers 0.4595496948676772 0.8595825799091356 0.390019180989708 1.0 0.8027820773173124 13 Q96RL7,P07196,Q12756 3 +Bilateral polymicrogyria 0.5397571749532319 0.8583714557290885 0.3906873840798239 1.0 0.8037912574101296 8 Q08209 1 +Abnormal pelvis bone morphology 0.5888086642599231 0.8549708940280766 0.3925672611610118 1.0 0.8052828368937446 2 Q08AM6 1 +Congenital hypothyroidism 0.7190321415673455 0.8535740528257019 0.3933410403739543 1.0 0.8052828368937446 3 P21281,P10644 2 +Decreased proportion of cd3 positive t cells 0.5877256317689483 0.850186718818069 0.3952212844646889 1.0 0.8059132075975673 2 O95394 1 +Stridor 0.574343737126898 0.8492573593960765 0.3957381022782003 1.0 0.8059132075975673 6 O43318 1 +Retinal hamartoma 0.5373219085333688 0.8479109900954548 0.396487543519247 1.0 0.8059132075975673 8 P31749 1 +Aplasia hypoplasia of the gallbladder 0.7171277816626214 0.8468617419994597 0.3970721891447555 1.0 0.8059132075975673 3 P18583 1 +Abnormality of hair growth 0.5731320301544038 0.8444209505414201 0.3984342192186023 1.0 0.8061714578632329 6 Q9UQ13,P36507 2 +Hand tremor 0.4895356641762238 0.8433842696719922 0.399013566587302 1.0 0.8061714578632329 11 Q9UNE7,P07196 2 +Abnormal circulating carbohydrate concentration 0.3657694125012168 0.8432763788146972 0.399073890329741 1.0 0.8061714578632329 36 O75489,O43676,Q70HW3,Q86Y39,P51608,Q9NX14 6 +Tachycardia 0.4078589493570442 0.8429676427223857 0.3992465406235281 1.0 0.8061714578632329 21 P14923,Q9NX14,P35609,P04899,P23786,P15924 6 +Distal lower limb muscle weakness 0.4284523714170807 0.8415884312031179 0.4000183670824113 1.0 0.8063900719289777 17 P07196,P00846 2 +Vomiting 0.3154481309561284 0.8413340678345348 0.4001608103729013 1.0 0.8063900719289777 83 O75489,O94761,O43676,Q86Y39,Q9NWH9,Q9HCC0,P00846,Q9NX14 8 +Narrow mouth 0.3405996424527484 0.840592917281402 0.4005760279325669 1.0 0.806866916718385 62 Q15392,O75844,Q9H9Y6,P31749,Q96ST3,O94761,Q9NVI7,P51608,Q9NX62 9 +High narrow palate 0.385191528501754 0.8382621870270234 0.4018834677735967 1.0 0.8075335266658098 31 O43318,Q96ST3,O94761,O60762,Q71SY5 5 +Anteverted ears 0.584837545126349 0.8374549885614635 0.4023368677566927 1.0 0.8075335266658098 2 P27635 1 +Pendular nystagmus 0.570987366734703 0.8358713837851166 0.4032272625958226 1.0 0.8085426749884875 6 P00846 1 +Abnormality of the musculature of the lower limbs 0.398127048727092 0.8356060999852849 0.4033765359504317 1.0 0.8085426749884875 26 Q96RL7,P20936,P07196,P00846 4 +Abnormality of the carpal bones 0.4376375755986416 0.8341528613284878 0.4041948503777588 1.0 0.8094646870597138 14 O94761 1 +Obstructive sleep apnea 0.502942156252369 0.8315984760048496 0.4056356226085489 1.0 0.8109866241137842 10 Q96KP1 1 +Contractures involving the joints of the feet 0.4220140402798731 0.8311546939152288 0.4058862453495666 1.0 0.8109866241137842 18 P14923,Q9Y3E5,Q8N2K0,P15924 4 +Kyphoscoliosis 0.3528183817556223 0.8308970049129717 0.4060318157913634 1.0 0.8109866241137842 48 O75844,O94761,P31749 3 +Choreoathetosis 0.3868332658133299 0.8280382275580518 0.4076488509331635 1.0 0.8120090529500105 30 P04350,Q4G0N4,Q6IA86,P22033,Q96RL7,P00846,Q9H1B7,Q5XKP0,P51608,P18074 10 +Aplasia hypoplasia of the extremities 0.2892129360883068 0.8277585856533441 0.4078072330593696 1.0 0.8120090529500105 153 O95202,Q03164,O94761,P18077,Q9Y5P4,Q9NX62,P62899,O75844,Q15392,Q96ST3,O60762,Q96HY6,Q5JRA6,P21281,O43318,P62244,Q9NWH9,Q96A33,Q07864,P61353,P42766,Q15427,P51608 23 +Craniosynostosis 0.3727159984599252 0.8274509200187083 0.4079815294813023 1.0 0.8120090529500105 34 P21281,O43318,P31749,O94761,Q08209,Q9NX62 6 +Aplasia hypoplasia of the optic nerve 0.410898202961628 0.8263094172476306 0.4086285927756115 1.0 0.8125809780634738 20 Q96KP1,P07196,Q9NVI7,P36507,Q00839,O95721 6 +Abnormal brainstem mri signal intensity 0.4251937213509634 0.822899393617509 0.4105652075757453 1.0 0.8145224227362214 17 O75489,O43676,Q86Y39 3 +Intellectual disability progressive 0.4849858054696409 0.8215898096095164 0.4113103909636746 1.0 0.8146113825289031 11 Q15067,O95721,P46100,P51608,Q9NX14 5 +Stroke 0.3929537084423009 0.8179866146533299 0.4133648304470911 1.0 0.8173226713172683 27 O75844,P51970,P51608,P22033,O76024,O95721 6 +Kinetic tremor 0.3822195244850079 0.8165501942062392 0.4141855277050861 1.0 0.8176831915868292 31 Q8N2K0,O75027 2 +Thyroiditis 0.5480624134763228 0.8162796913315121 0.414340187014292 1.0 0.8176831915868292 7 P31749 1 +Oculogyric crisis 0.4838475396808057 0.8161512669126709 0.4144136252956472 1.0 0.8176831915868292 11 Q08209,P61457 2 +Proptosis 0.3520239847414915 0.8143104821145837 0.4154671062883035 1.0 0.8176831915868292 45 O75844,O94761,Q8IZT6 3 +Talipes valgus 0.7074756229685834 0.8129992412473324 0.4162184931898651 1.0 0.8176831915868292 3 P49589,Q9H2M9 2 +Abnormal monocyte morphology 0.5790613718411503 0.8121101797399743 0.4167284124897321 1.0 0.8176831915868292 2 Q9UJV9 1 +Monocytosis 0.5790613718411503 0.8121101797399743 0.4167284124897321 1.0 0.8176831915868292 2 Q9UJV9 1 +Pyoderma gangrenosum 0.5790613718411503 0.8121101797399743 0.4167284124897321 1.0 0.8176831915868292 2 O75083 1 +Pharyngitis 0.5790613718411503 0.8121101797399743 0.4167284124897321 1.0 0.8176831915868292 2 P01889 1 +Hypoplasia of the brainstem 0.394575118044024 0.8117393116265463 0.4169412319621639 1.0 0.8176831915868292 26 Q9UPN3,Q96KP1,Q13057,P07954,Q9Y3C6,Q53EZ4,Q10713,Q9NXE4 8 +Iron deficiency anemia 0.5646537827562856 0.8107061082775546 0.4175344646969741 1.0 0.8176831915868292 6 P46100 1 +Plantar hyperkeratosis 0.3744230215194628 0.8102289183431818 0.4178086199179598 1.0 0.8176831915868292 33 P31749,Q06136,P14923,O94761,P36507,P35609,P15924 7 +Delayed puberty 0.3494383144202876 0.8098614765368208 0.4180197948793012 1.0 0.8176831915868292 50 O75844,O43318,Q01968,P49589,Q9NVI7,Q8IWS0,Q15800,P40763,Q9Y3E5,Q9UNE7 10 +Breast carcinoma 0.4175223638225479 0.8048944135761235 0.420880612393848 1.0 0.8194955114532372 18 Q07864,P31749 2 +Full cheeks 0.3835300222570171 0.8043844412264981 0.4211749839739744 1.0 0.8194955114532372 30 Q96JJ3,P54577,O43318,Q01968,Q12756,P10412,P54886,O60762,P36507,P18583 10 +Limb joint contracture 0.3088371377530028 0.8037934539377805 0.4215162709289084 1.0 0.8198065054054275 85 Q14738,P07196,Q5JTV8,Q71SY5,O75844,Q15392,O60828,O60762,P18074,Q8N2K0,O43318,Q01968,P40763,P23786,P32322,P14923,Q8IWS0,P51608,Q9Y3E5,Q86XL3,P15924 21 +Hyperactive patellar reflex 0.5445554229823641 0.8018832330725504 0.4226205059007606 1.0 0.8205412314824395 7 P13073,P54886,Q5T440 3 +Facial asymmetry 0.3794370991784676 0.7963011905616326 0.4258569937586816 1.0 0.8255146962805437 31 O95202,Q03164,P31749,Q9H9Y6,Q96ST3 5 +Acne 0.4637290279282473 0.7962966187695891 0.4258596504140057 1.0 0.8255146962805437 12 P01889,Q9NZ08,Q92542,Q92890,P17612,Q9H488 6 +Delayed eruption of teeth 0.3497911450532143 0.7930479606454778 0.4277498803624047 1.0 0.8255146962805437 39 O75844,P21281,Q96JJ3,Q01968,O94761,P51608,Q5JRA6 7 +Abnormal oral frenulum morphology 0.4296331509989703 0.7906812866605956 0.429129998851018 1.0 0.8255146962805437 14 O75844 1 +Gray matter heterotopia 0.3984052241668918 0.7901799339507815 0.4294226930087443 1.0 0.8255146962805437 22 Q8IZT6,P31749 2 +Thin ribs 0.462481280267251 0.7901169210465597 0.4294594887058878 1.0 0.8255146962805437 12 O75844 1 +Medial flaring of the eyebrow 0.7008540967400211 0.7899323154236987 0.4295672976882598 1.0 0.8255146962805437 3 Q96ST3 1 +Myofibrillar myopathy 0.5590753385402869 0.7886510610325055 0.4303159785501833 1.0 0.8260188364627779 6 P31749 1 +Facial cleft 0.6834855136825577 0.7877441295574522 0.4308463872312797 1.0 0.8265664448029393 4 Q9H9Y6 1 +Shuffling gait 0.5080805978595996 0.785943328930995 0.4319006886942826 1.0 0.8268468472209691 9 O75844 1 +Abnormal localization of kidney 0.3430888704829821 0.7856985886367653 0.4320440902793452 1.0 0.8268468472209691 55 O43318,P62244,P61353,P42766,O94761,P18077,P62899 7 +Median cleft palate 0.5725631768953018 0.7837988404794279 0.4331581543408624 1.0 0.8268468472209691 2 Q14739 1 +Difficulty walking 0.3277434144909403 0.7833269300938811 0.4334351529133236 1.0 0.8268468472209691 69 Q13057,Q15067,P31749,P51608,Q8TD30,Q08209,P04792,Q8NC96,P00846,Q71SY5,Q9UNE7,O95140,O14773 13 +Abnormal blistering of the skin 0.4127042126386517 0.7768721597657844 0.4372341980715482 1.0 0.8303590192884636 18 Q06136,O94761 2 +Abnormal renal morphology 0.29323584637221 0.7700957533593521 0.4412430948909511 1.0 0.8354340516410362 225 Q03164,Q9Y276,Q53EZ4,O94761,Q16822,P52565,P18077,Q08209,P22033,P36507,P00846,Q71SY5,P62899,Q15392,Q9NQW6,Q5JRA6,P21281,O43318,Q01968,Q8IZT6,P31749,P62244,P39019,Q9NZ08,P23786,Q07864,P42695,P07954,P61353,P42766,Q15427,O14745,P46100,O95470 34 +Meningitis 0.6782738618281733 0.7696688889933047 0.441496329297754 1.0 0.8354340516410362 4 Q9NZ08,P02786 2 +Abnormal arterial physiology 0.3878493371726305 0.7668428291849024 0.4431749684322064 1.0 0.8370671017461155 26 O75844,Q9NZ08 2 +Chronic hepatic failure 0.6770373939040322 0.7653937121140902 0.444037136082946 1.0 0.8375735882563885 4 P55084,Q13043 2 +Abnormal saccadic eye movements 0.3953615350350046 0.7647782332849634 0.4444036113067293 1.0 0.8375735882563885 21 O75306,Q12756,Q10713,Q96RL7,P34897,O95140,O14773 7 +Branchial fistula 0.5663486936166517 0.7645233335504606 0.444555437060385 1.0 0.8375735882563885 5 Q9H9Y6 1 +Dehydration 0.4239617099672928 0.7601127743030877 0.4471871775095271 1.0 0.8398646928979852 14 Q01968,P54819,Q9Y2Q9,P22033,P40763,P82673,Q9H3U1,P35610 8 +Submucous cleft of soft and hard palate 0.3935776610860271 0.7597714792438015 0.4473911938328494 1.0 0.8398646928979852 22 Q15392,O75844,P49589,Q14738,Q9Y2W2,P36507,Q8WYQ5,P18583 8 +Failure to thrive in infancy 0.3703919550798961 0.7537675729663592 0.4509887984914029 1.0 0.8430150565097883 32 O94761 1 +Emotional lability 0.3434783311203538 0.7515035241104073 0.4523496806831986 1.0 0.8442761289060974 49 P31749,O75489,Q15165,Q96RL7,P51608 5 +Abnormal rectum morphology 0.3753241501825968 0.7461052927626693 0.455603812329183 1.0 0.8481326840145237 30 O94761,Q9NX14,Q07864,P31749 4 +Bifid uvula 0.357485208816485 0.7416357595740024 0.4583080513967383 1.0 0.8503637684642562 35 Q15392,O94761,P21281 3 +Short palm 0.3963339619079843 0.737775685285508 0.4606507710918528 1.0 0.8533624976364554 20 O60762,Q96ST3,O94761,O43318 4 +Increased serum lactate 0.3052526910345344 0.7377279981969075 0.4606797547001582 1.0 0.8533624976364554 94 Q9Y276,P14927,Q5JTZ9,Q9NVI7,Q6P4A7,P00846,Q9Y606,P51970,Q86Y39,Q5XKP0,Q9Y584,Q9UBX3,Q5JPH6,O14949,P13073,Q01968,O75489,Q70HW3,Q16795,O75306,Q99797,Q9Y2Z4,Q9Y2Q9,O75251,P51608,P35610 26 +Oligomenorrhea 0.5456619341868096 0.7360907282110861 0.4616754849451059 1.0 0.8536585167180365 6 Q9UNE7 1 +Broad alveolar ridges 0.6850848681834433 0.7355943997594198 0.461977571750656 1.0 0.8536585167180365 3 P21281,Q08AM6 2 +Anhidrosis 0.6681394509074944 0.7347854328622145 0.4624701801449635 1.0 0.8536585167180365 4 Q9Y276 1 +Abnormal nasal base 0.4665675025760405 0.7343654234184838 0.4627260541895981 1.0 0.8536585167180365 11 P21281,Q13868,Q96ST3,Q8TAQ2,Q08AM6 5 +Polysplenia 0.6847237269772422 0.7343605576770216 0.4627290189115696 1.0 0.8536585167180365 3 P54577,P57076 2 +Reduced consciousness confusion 0.3074401662607514 0.7325720592902484 0.4638194777394211 1.0 0.8546233280696185 107 P18077,P22033,Q9HCC0,P62899,P36551,Q12756,Q86Y39,Q9NX14,P62244,P31749,O75489,P39019,Q9NZ08,P31751,P40763,P23786,P61353,P42766,Q8TB37,O43676 20 +Submucous cleft soft palate 0.6833268766551013 0.7295929195294035 0.4656390514706223 1.0 0.8562056185399002 3 P18583 1 +Spontaneous recurrent epistaxis 0.5595667870036047 0.7278856430134661 0.4666835924560044 1.0 0.8574528144433623 2 P35579 1 +Small hand 0.3790559629030683 0.7241620752045432 0.4689662385766375 1.0 0.8600044537205807 27 P51608,Q96ST3,O94761 3 +Abnormal cerebral vascular morphology 0.3273161180132083 0.7223598638172634 0.4700732564807623 1.0 0.8608800051804152 63 O75844,P20936,P07954,P31749,P51608,P22033,O76024,Q9HCC0,Q8NBJ5,O95721,P23786 11 +Premature ventricular contraction 0.5418777676325572 0.7213949722979951 0.4706665390569342 1.0 0.8612682962572819 6 P14923 1 +Cerebellar cortical atrophy 0.5577617328519802 0.720201159899891 0.4714011498706822 1.0 0.8618528453324585 2 O75312 1 +Facial hypotonia 0.5070206914973643 0.7196448711504485 0.4717436772383043 1.0 0.8618528453324585 8 P51608,Q14738 2 +Stroke like episode 0.6636560693641494 0.7194724910286007 0.4718498458331581 1.0 0.8618528453324585 4 O76024,P51970,P00403 3 +Arthrogryposis multiplex congenita 0.3761076685144364 0.7191894437107481 0.4720242027091126 1.0 0.8618528453324585 28 Q15392,O75844,Q12756,Q53EZ4,Q08209,P40763,P18074 7 +Gingivitis 0.663463137231006 0.7188152538939476 0.4722547577575924 1.0 0.8618528453324585 4 Q01968 1 +Infantile spasms 0.3843567413492228 0.7187072706651032 0.4723213025770623 1.0 0.8618528453324585 24 Q9Y3C6,P51608,Q12756,P00846 4 +Abnormal nerve conduction velocity 0.3580858316714802 0.7153925760200529 0.4743664985903979 1.0 0.8631445189816422 34 Q12756,P07196,P04792,Q71SY5,Q9Y3E5,Q8N2K0 6 +Adrenal overactivity 0.6622497686409043 0.71468514174783 0.4748036209154955 1.0 0.8632445711453557 4 P17612,Q01968 2 +Limited elbow movement 0.3677850777030358 0.7124403746641275 0.4761921214410327 1.0 0.8650727803259293 31 Q15427,O94761 2 +Abnormal cortical bone morphology 0.4089351888588596 0.7094074380599626 0.4780716733157883 1.0 0.8666597508285036 16 Q8IZT6,P31749 2 +Autism 0.3399267338968184 0.7086976957854197 0.478512095059435 1.0 0.8666639987670925 40 P31749,Q96ST3,P46100,Q8NC96,P51608 5 +Lower limb asymmetry 0.5212880048600765 0.7076103954933786 0.4791872354486153 1.0 0.8666639987670925 7 P31749 1 +Laryngeal dystonia 0.6768009165937942 0.7074207487651238 0.4793050465517274 1.0 0.8666639987670925 3 Q96RL7 1 +Abnormal peripheral nervous system physiology 0.3397018094014521 0.7059457820495456 0.4802218551147008 1.0 0.8675359172448582 44 O95140,Q12756,P07196,O95721,P04792,Q96RL7,Q71SY5,Q9Y3E5,Q8N2K0 9 +Renal tubular dysfunction 0.366440103075341 0.7028694046152648 0.482137139598255 1.0 0.868019508991881 31 Q01968,Q9Y276,Q8TB37,O75489,O43676,Q86Y39,P40763,Q9NX14 8 +Hamartoma of the eye 0.488312816513001 0.7000244855121454 0.4839120131822372 1.0 0.868019508991881 9 P31749 1 +Abnormal sputum 0.5187975772864027 0.6976649691233816 0.4853867406870842 1.0 0.868019508991881 7 Q9NZ08 1 +Abnormality of hair texture 0.3373043716073136 0.6968670573032777 0.4858859955822838 1.0 0.868019508991881 49 O75844,Q9Y276,Q14004,Q01968,P14923,Q96ST3,Q9NVI7,Q9Y5P4,Q96A33,P36507,P15924 11 +Foot dorsiflexor weakness 0.3705153926083556 0.6955600847093427 0.4867043705989922 1.0 0.868019508991881 29 P35609,Q9BQT8,P07196 3 +Neoplasm of the eye 0.4275550768779653 0.6948724378840286 0.4871352469597774 1.0 0.868019508991881 13 P07954,P31749 2 +Basal cell carcinoma 0.4726596281213256 0.6942785441029882 0.487507543827296 1.0 0.868019508991881 10 O94761 1 +Neoplasm of the rectum 0.4115965563785995 0.6942473665201657 0.487527092501316 1.0 0.868019508991881 14 P31749 1 +Recurrent pneumonia 0.3887519786859235 0.6923871959315728 0.4886942045279236 1.0 0.868019508991881 20 Q71SY5,Q13432 2 +Abnormal ureter morphology 0.4057998732345892 0.6923192827311355 0.4887368432397476 1.0 0.868019508991881 16 O75844,Q53EZ4,P23786 3 +Abnormal morphology of the limbic system 0.4571906675597833 0.690689843336776 0.4897604734464202 1.0 0.868019508991881 11 Q08209,Q96RL7 2 +Lower limb amyotrophy 0.4048561357382861 0.6871924060361583 0.4919614891635784 1.0 0.868296874346982 16 P04792,P07196,Q9NVI7,Q12756 4 +Increased skull ossification 0.549819494584832 0.6866455974640605 0.4923060871789531 1.0 0.868296874346982 2 P54802 1 +Neuronal loss in basal ganglia 0.6704989174228271 0.6861757071788404 0.4926023147803322 1.0 0.868296874346982 3 Q99986 1 +Abnormal venous morphology 0.3755887470812084 0.6861716928500442 0.4926048458996763 1.0 0.868296874346982 26 P20936,P57076,P31749,P32322,Q71SY5,Q13043,P98175 7 +Abnormality of the plantar skin of foot 0.3371855532847876 0.6858770358670226 0.4927906524056133 1.0 0.868296874346982 40 P21281,P31749,Q06136,P14923,O94761,P35609,P15924 7 +Esophagitis 0.5326174402977276 0.6857060424460178 0.4928984956477706 1.0 0.868296874346982 6 Q8NBU5 1 +Elbow ankylosis 0.5494584837545073 0.6851306328556008 0.4932614915732463 1.0 0.868296874346982 2 P16435 1 +Humeroradial synostosis 0.5494584837545073 0.6851306328556008 0.4932614915732463 1.0 0.868296874346982 2 P16435 1 +Elevated pulmonary artery pressure 0.3872686265580368 0.6835722212933563 0.4942453308114054 1.0 0.8688619894512122 20 O75844 1 +Large earlobe 0.5319210766523823 0.6830388348846598 0.494582303387205 1.0 0.8688619894512122 6 Q15392,Q8IWS0 2 +Hirsutism 0.3335024692535396 0.6829780897323321 0.4946206875769507 1.0 0.8688619894512122 53 Q03164,P31749 2 +Absent fingernail 0.4981677880749254 0.682972215563089 0.494624399483957 1.0 0.8688619894512122 8 P21281,P14923 2 +Short digit 0.2997388539999915 0.6821161400038384 0.4951655156584795 1.0 0.8694744655052509 127 O95202,Q03164,O94761,P18077,Q08209,Q9NX62,P62899,O75844,Q92643,Q96ST3,Q5JRA6,P21281,O43318,P62244,P31749,Q06136,P61353,P42766,Q15427,P46100,P51608 21 +Thickened skin 0.3008471011709932 0.6790929879225496 0.4970789451538422 1.0 0.8708029231227459 95 O75844,P31749,Q06136,P51648,P14923,O94761,Q10567,P31751,Q15800,O95470,P35609,Q9P265,P15924 13 +Abnormality of metacarpophalangeal joint 0.5415197544092935 0.671177630519804 0.5021073772814679 1.0 0.8762151914089115 5 O43318,O60828 2 +Generalized dystonia 0.6634163958107665 0.6625061341128429 0.5076469049089054 1.0 0.8827614582731176 3 P04350,P82663 2 +Abnormal thumb morphology 0.2990453649515058 0.6615120294400133 0.5082840026718567 1.0 0.8827614582731176 94 O95202,Q13868,Q8NBU5,O94761,P18077,Q71SY5,P62899,A5YKK6,O60828,Q96ST3,P54886,P21281,O43318,P62244,P39019,Q06265,P61353,P42766,Q15427,Q9NXE4,Q9Y3E5,Q86XL3,Q9UNE7,P18583 24 +Poor head control 0.3180271305309814 0.6587317928292244 0.5100680133733331 1.0 0.8827614582731176 65 P13073,O75306,Q06265,P51970,P57678,Q8TB37,O75489,P00374,O43676,Q86Y39,Q6IA86,Q08209,Q9Y3C8,Q8NC96,Q5XKP0,O95721,Q9NX14 17 +Abnormality of upper limb joint 0.2995091785531377 0.658592957781942 0.5101571862662926 1.0 0.8827614582731176 96 O95202,O75844,Q15392,O43318,Q03164,Q01968,P31749,P51608,O94761,P07196,Q15427,Q71SY5,Q9Y3E5 13 +Abnormally large globe 0.525205744392933 0.6574443107380813 0.5108952678753202 1.0 0.8833619671874079 6 Q01968,P31749 2 +Upper eyelid coloboma 0.5422382671480088 0.6550298200361058 0.512448554892059 1.0 0.884693378296646 2 Q13428 1 +Dysmetria 0.3333427676975364 0.6529318188400244 0.5138002347611637 1.0 0.8860112445232586 45 O75027,Q6P4A7,Q96TA2,Q9Y3E5,Q9UNE7,Q8N2K0,O14773 7 +Mitochondrial myopathy 0.3703984615734386 0.6525548269810012 0.5140433159053437 1.0 0.8860922171920422 26 O75489,O43676,Q86Y39,P00846 4 +Abnormal circulating hormone concentration 0.3022166180466283 0.650624785987212 0.5152887263662813 1.0 0.8872235006565774 81 O75844,Q03164,Q01968,P31749,Q96ST3,P31751,P46100,P51608,Q07864 9 +Increased connective tissue 0.5053168652677339 0.6444003429099823 0.5193158622407197 1.0 0.8917784361853179 7 P07196 1 +Subcortical heterotopia 0.6567448184870985 0.6404219192515158 0.5218983363706013 1.0 0.8941309194926194 3 O00139 1 +Subcortical band heterotopia 0.6567448184870985 0.6404219192515158 0.5218983363706013 1.0 0.8941309194926194 3 O00139 1 +Abnormal pancreas size 0.5199207899506932 0.6374703643577583 0.523818507785442 1.0 0.8941309194926194 6 Q9Y3E5,P40763 2 +Hyperventilation 0.5199007117658967 0.6373947770522146 0.5238677295974679 1.0 0.8941309194926194 6 P00846 1 +Head tremor 0.4007030369882927 0.6372628975156988 0.523953614110946 1.0 0.8941309194926194 14 Q9UNE7,P07196 2 +Facial hypertrichosis 0.3294849972616684 0.6366088110425074 0.5243796844979158 1.0 0.8941309194926194 51 Q03164 1 +Hypogonadism 0.3036642588907174 0.6365588599166999 0.5244122298381431 1.0 0.8941309194926194 79 O75844,Q9Y276,P31749,O94761,O95721,Q8IWS0,O76024,Q9H7N4,P46100,O95470,P51608,Q9UNE7,Q07864 13 +Narrow palate 0.3311789437568957 0.6363863178955385 0.5245246564619639 1.0 0.8941309194926194 40 P21281,Q96JJ3,O43318,Q01968,Q96ST3,O94761,O60762,Q71SY5 8 +Neoplasm by histology 0.2946771264135786 0.6353456058555529 0.525203035558719 1.0 0.8941309194926194 89 Q15392,P21281,Q96JJ3,P62244,P61353,P42766,P31749,P39019,O94761,P18077,P62899,Q07864 12 +Aortic regurgitation 0.3730212704595488 0.6328077724734898 0.5268591805062786 1.0 0.8948940014847853 22 O75844 1 +Sloping forehead 0.3308357846454243 0.6321570616900658 0.5272842518027301 1.0 0.8948940014847853 41 Q96KP1,P42695,Q13057,Q8IZT6,Q9BSJ2,Q9NXE4,Q16851,P23786,Q86XL3 9 +Broad forehead 0.3585511446575901 0.6295978162820155 0.5289577526770468 1.0 0.895652341118803 30 O94761 1 +Low anterior hairline 0.3295471312122507 0.629349808082804 0.5291200697743259 1.0 0.895652341118803 49 P21281,O43318,P62244,P61353,Q9H9Y6,P42766,P18077,P62899 8 +Right ventricular cardiomyopathy 0.6367129616096199 0.6292048349998941 0.5292149638961734 1.0 0.895652341118803 4 P14923 1 +Extramedullary hematopoiesis 0.6533044420368292 0.6291179357391263 0.5292718491500112 1.0 0.895652341118803 3 P27797,P98175 2 +Joint contractures involving the joints of the feet 0.4713043610186231 0.6278680019151226 0.5300904141360281 1.0 0.895652341118803 9 P14923,Q8IWS0,P15924 3 +Congenital hip dislocation 0.3683217484869137 0.6274748430501458 0.5303480215314931 1.0 0.895652341118803 25 O43318,P57678,P32322,O94761,Q14738,Q9Y3E5 6 +Unilateral renal agenesis 0.3901318747326289 0.6267335827873494 0.5308338864219166 1.0 0.895652341118803 17 P42695,Q8IZT6,Q9Y2W2,Q15427,Q86XL3,P18583 6 +Abnormal cardiac ventricular function 0.3934934477131526 0.6261233006980368 0.5312340700985858 1.0 0.895652341118803 16 O75844,P46100 2 +Lymphopenia 0.3718816268106074 0.625909257539799 0.5313744620444112 1.0 0.895652341118803 22 P26038,Q13432,O95470 3 +Falls 0.4839872876184058 0.6251747913371526 0.5318563449750047 1.0 0.895652341118803 8 Q9BQT8 1 +Abnormal uvula morphology 0.3295563284003867 0.6251382767897786 0.5318803079286738 1.0 0.895652341118803 39 Q15392,O94761,P21281 3 +Low levels of vitamin d 0.4703362719541581 0.6238185060126141 0.5327467847155374 1.0 0.8961559448875042 9 Q01968 1 +Muscle fiber inclusion bodies 0.4560641689789994 0.6212988564847998 0.5344030059539948 1.0 0.896324956577353 10 O43676 1 +Inappropriate laughter 0.4830088288180723 0.6212338569981618 0.5344457659108102 1.0 0.896324956577353 8 P46100 1 +Frontotemporal cerebral atrophy 0.5339350180505358 0.6209076071694746 0.5346604156653312 1.0 0.896324956577353 2 P55072 1 +Spoken word recognition deficit 0.5339350180505358 0.6209076071694746 0.5346604156653312 1.0 0.896324956577353 2 P55072 1 +Abnormality of ocular smooth pursuit 0.3849795884858532 0.6193687310836993 0.535673475456897 1.0 0.8973573459822991 18 O14773 1 +Congenital nystagmus 0.4267487319384676 0.6173225687875121 0.5370219835380035 1.0 0.8976194308637439 12 P00846 1 +Ventricular arrhythmia 0.3537804431251228 0.6140948960217846 0.5391526208187996 1.0 0.8997105087311238 31 P14923,P00846,P35609,P04899,Q9NX14 5 +Paresthesia 0.3839272570282454 0.6135424063141943 0.5395177520314114 1.0 0.8997105087311238 18 Q9NZ08,P07196 2 +Abnormality of the forearm 0.3360353054698017 0.6083194830907528 0.542975601569307 1.0 0.9035593988545596 36 O95202,O43318,O94761,Q15427,P36507 5 +Headache 0.3198684731895568 0.605410771808225 0.5449060955294298 1.0 0.9036246447777 59 Q02241,P20936,P07954,P31749,Q9NZ08,Q9NQW6,P00846,P23786 8 +Ichthyosis 0.3494481618851822 0.6032813586492144 0.5463215319014987 1.0 0.9045899454959476 32 P51648,Q10567,Q9UQ13,Q15800,P36507,O95470,O95721,P15924 8 +Agenesis of corpus callosum 0.3069188565592961 0.6013894229382012 0.5475806418502769 1.0 0.9045899454959476 73 O95202,Q15392,P42695,P07954,Q14004,Q8IZT6,P32322,Q9Y3C6,Q10713,O94761,Q9NX14,P23786,P46100,Q00839,Q71SY5,P18074,Q86XL3,P29372 18 +Abnormal uterus morphology 0.3654676556851932 0.6002507885713617 0.548339110231943 1.0 0.9045899454959476 24 Q07864,P31749 2 +Chorioretinal dysplasia 0.5218040541439959 0.5991949300785674 0.5490429032580066 1.0 0.9045899454959476 5 Q9NX14 1 +Distal lower limb amyotrophy 0.4367115982098385 0.5974572837068004 0.5502021182432191 1.0 0.9045899454959476 11 P04792,P07196 2 +Amblyopia 0.3878134230760405 0.5960961443877955 0.5511109997562917 1.0 0.9054553615990384 16 O43318,P10412,Q01968,Q96TA2,Q71SY5,Q9NX14 6 +Abnormality of the periungual region 0.6431363352121746 0.5960632623944337 0.5511329653725769 1.0 0.9054553615990384 3 Q12756 1 +Biparietal narrowing 0.4635852346004083 0.5957687460206161 0.5513297254889231 1.0 0.9054553615990384 9 Q00839,Q10713,P36507,Q12756 4 +Ulnar deviation of the hand or of fingers of the hand 0.4623773444851883 0.5907863064456977 0.5546636112238303 1.0 0.9055366750492064 9 O43318 1 +Asymmetric growth 0.4488111485578071 0.5900400280690196 0.5551638139496493 1.0 0.9055366750492064 10 P20936,P31749 2 +Abnormality of the elbow 0.3245581814353957 0.589936934191128 0.5552329312766648 1.0 0.9055366750492064 50 Q15427,O94761,Q03164 3 +Persistent head lag 0.4909169323362627 0.5886971880340928 0.5560644245691793 1.0 0.9055366750492064 7 P51608,Q5XKP0 2 +Focal impaired awareness seizure 0.3830784627353857 0.5886817532544444 0.55607478044823 1.0 0.9055366750492064 17 P21281,Q08209 2 +Eczema 0.3438842535247903 0.5854672029362507 0.5582336130679408 1.0 0.9056569979980664 33 Q9UQ13,P26038,Q9HCC0,P40763,Q07864 5 +Retinal dystrophy 0.3249694381391743 0.5854160768741443 0.5582679812803486 1.0 0.9056569979980664 47 P22570,Q13868,Q9Y276,P57076,Q9NQ48,Q15067,Q10713,Q8TC12,P00846,Q9NX14,Q8N2K0 11 +Congenital malformation of the left heart 0.524548736462088 0.5830255017816736 0.5598761329474267 1.0 0.9067859628003606 2 Q8N3U4 1 +Pedal edema 0.5171866825033054 0.582660454548679 0.5601218995770902 1.0 0.9067859628003606 5 Q12756 1 +Micromelia 0.3850250820061773 0.58149011526657 0.5609101783195807 1.0 0.9070122353786204 16 Q15392,Q07864 2 +Lower extremity joint dislocation 0.309123669677771 0.5808144694632779 0.5613655020313382 1.0 0.9074237345894762 67 O95202,O75844,O43318,Q01968,P31749,O94761,Q15427,Q96A33,Q9Y3E5 9 +Neoplasm of the genitourinary tract 0.3149465587329212 0.5796837885499098 0.5621278776671437 1.0 0.9080063465499304 61 P62244,P61353,P31749,P42766,P39019,Q9NWH9,P18077,P62899,Q07864 9 +Anonychia 0.4183637762627095 0.5782324667088 0.5631071819136064 1.0 0.9089382807737312 12 P21281,P14923 2 +Increased csf lactate 0.3243795811962398 0.577801105007638 0.563398409164066 1.0 0.9090373294682332 43 P13073,P51970,Q8TB37,O75489,O43676,Q86Y39,P00846,P51608,Q9NX14 9 +Abnormal proximal phalanx morphology of the hand 0.515089750601891 0.5751956510549099 0.5651589836894899 1.0 0.9108779417531768 5 Q08AM6,P42345 2 +Finger syndactyly 0.3541346570630956 0.5736361798323911 0.566214023563389 1.0 0.9108779417531768 28 P14923,Q71SY5,Q15427,P31749 4 +Distal muscle weakness 0.3188783041790454 0.5719556079079816 0.5673520495456388 1.0 0.9109201601743336 56 Q9BQT8,Q86U42,P07196,P04792,Q96RL7,P00846,P35609,Q71SY5,Q9Y3E5,O95140 10 +Symphalangism affecting the phalanges of the hand 0.6350003520296574 0.570018758517397 0.5686649752220099 1.0 0.9109201601743336 3 O60828 1 +Proximal symphalangism 0.6350003520296574 0.570018758517397 0.5686649752220099 1.0 0.9109201601743336 3 O60828 1 +Hypertelorism 0.2727086833482742 0.5699180661958371 0.5687332708803936 1.0 0.9109201601743336 172 O95202,Q03164,Q9H9Y6,O94761,P18077,Q08209,P36507,Q71SY5,P62899,O75844,Q14004,Q96ST3,O60762,Q96KP1,P21281,O43318,P62244,Q15067,P31749,P39019,Q96A33,P40763,O95721,Q06265,P61353,P42766,P46100,Q9Y3E5 28 +Recurrent viral infections 0.4165105192661302 0.5696837872346955 0.5688921882922076 1.0 0.9109201601743336 12 Q13432 1 +Gynecomastia 0.3756460215327298 0.5681617704353803 0.5699251274759523 1.0 0.9109201601743336 18 Q8IWS0,P51608,P31751,P31749 4 +Abnormality of vitamin d metabolism 0.4429725801186074 0.5651935952778036 0.5719420925417606 1.0 0.9110077107173082 10 Q01968 1 +Intrauterine growth retardation 0.2711060311026469 0.5650132263796022 0.5720647679490556 1.0 0.9110077107173082 168 O95202,Q03164,Q9Y276,O94761,Q6P4A7,O75844,Q15392,O75027,Q96ST3,Q86Y39,Q9NX14,Q9Y584,Q5SRE5,O75489,P49589,P39019,Q8TCJ2,P40763,Q07864,Q06265,Q8TB37,P14923,O43676,Q9Y2Q9,Q15427,P15924 26 +Abnormality of the calf 0.3210680520961184 0.5638600444016858 0.5728493840773718 1.0 0.9110077107173082 51 Q01968,O94761,Q9NWH9,Q15427,P36507,P46100,Q96HY6 7 +Abnormal muscle fiber morphology 0.3108567237467426 0.5635510005247506 0.5730597418899048 1.0 0.9110077107173082 63 Q9Y276,O43676,P07196,Q9H2D1,Q70HW3,O75190,Q96RL7,P00846,P35609,Q5JTV8,P23786,Q5JPH6 12 +Corneal erosion 0.6160101663566618 0.5622291298532917 0.5739599168752223 1.0 0.9113331091062148 4 P51648 1 +Abnormality of the alveolar ridges 0.4837202603696677 0.5613818543965572 0.5745372513501084 1.0 0.9113331091062148 7 Q15392 1 +Downslanted palpebral fissures 0.2926981081501238 0.5605005950735155 0.5751380338847056 1.0 0.9114253374574184 121 O95202,O75844,Q15392,P21281,O43318,Q03164,P31749,Q9H9Y6,Q96ST3,O94761,P51608,P39019,Q08209,Q15427,O60762,P36507,Q8NC96,Q71SY5 18 +Abnormal talus morphology 0.3806387142218017 0.5587034927632388 0.5763640952276174 1.0 0.9120268414426944 16 O75844,Q9NXE4,P18074,Q5SRE5,P98175 5 +Abnormal tongue morphology 0.3112951516680515 0.5564179464269188 0.5779251732334192 1.0 0.913303071886212 62 O75844,P21281,P31749,P07196,Q96RL7,Q96A33,P46100,Q71SY5 8 +Abnormal patella morphology 0.3577730695951573 0.553407738522679 0.5799842411284026 1.0 0.9135072839185104 24 O94761,Q01968 2 +Joint contracture of the hand 0.3208591429927333 0.5532513944949258 0.5800912787875623 1.0 0.9135072839185104 40 Q15392,O75844,O43318,Q01968,P07196,Q71SY5 6 +Nasogastric tube feeding 0.3584356447954155 0.5507424055989277 0.5818102706935977 1.0 0.9149386714213974 23 Q71SY5,O94761 2 +Blindness 0.3034570825826225 0.5496994270281371 0.5825255499225246 1.0 0.9149801342439692 71 P22570,P31749,O75489,Q9NZ08,Q86Y39,O43676,P00846,Q9NX14 8 +Abnormal cortical gyration 0.2929820633596723 0.5486094866460678 0.5832734740825023 1.0 0.9149801342439692 112 Q10713,O94761,Q08209,Q71SY5,Q15392,Q12756,Q9Y3C6,P21281,Q8IZT6,O95721,P23786,P42695,P07954,Q96F86,Q9BSJ2,Q15427,Q9NXE4,O00139,P51608,Q86XL3,P18583 21 +Progressive spastic paraplegia 0.3555304677070567 0.5481758082543083 0.583571191454564 1.0 0.9149801342439692 25 P00846 1 +Hypocholesterolemia 0.4797979736806472 0.5466546995923073 0.5846159818655037 1.0 0.9149801342439692 7 Q9NVI7 1 +Heart block 0.3633879097181381 0.5451977190152072 0.585617540147005 1.0 0.9151676818928984 20 P35609,P04899,P14923 3 +Abnormal scapula morphology 0.3198720575421622 0.5448959376768288 0.5858250903665239 1.0 0.9151676818928984 48 O43318,P62244,P61353,P42766,P07196,P18077,Q15427,P62899 8 +Stomatitis 0.3967297074679929 0.5436055219851491 0.586712959053582 1.0 0.9159534032495106 13 Q9NZ08,P10644,P40763 3 +Hypopigmented macule 0.5059252265159199 0.5429113136206462 0.5871908659477412 1.0 0.916081586549684 5 P20936,Q15149,Q15233 3 +Abnormal urinary color 0.5057775057592049 0.5423956246335003 0.587545993167726 1.0 0.916081586549684 5 P23786 1 +Emg neuropathic changes 0.3583661831694688 0.5423083312241068 0.5876061172689209 1.0 0.916081586549684 21 P04792,Q99986,Q96RL7,O14773 4 +Gastric ulcer 0.6254412278648513 0.5399112790662424 0.5892582190471365 1.0 0.9166000652644548 3 O76024 1 +Abnormality of the diencephalon 0.3524924740036856 0.5395938509521125 0.5894771581471843 1.0 0.9166000652644548 26 Q96KP1,P31749 2 +Retinopathy 0.3570511854455583 0.5377860067862605 0.5907247936943238 1.0 0.9171459168078884 22 O95202,P51648,Q9NZ08,O60762,P40763,P18074,P00846,Q5JRA6 8 +Wide intermamillary distance 0.3617917514349577 0.5362229477176003 0.5918044756509842 1.0 0.9176938027829488 20 Q9Y5P4 1 +Abnormal blood monovalent inorganic cation concentration 0.3784786360495362 0.5354724747390534 0.5923231861341618 1.0 0.917973143295344 15 P36551,Q01968,Q13423,O95551,P35658,O00170,Q9H3U1,O95163 8 +Anal atresia 0.3546762082501464 0.5348246085132726 0.5927711447655126 1.0 0.9181145121873796 24 Q96ST3,O94761 2 +Abnormality of circulating glucocorticoid level 0.4351543414845062 0.5324009112465277 0.5944483541874952 1.0 0.9196092508033926 10 P31749,Q9H0R6,Q13423,P17612,P10644 5 +Tinnitus 0.407485942906977 0.5285652070607965 0.5971071015820248 1.0 0.920083347135832 12 O95140,P31749 2 +Premature loss of teeth 0.4074265557495177 0.5282975477580939 0.5972928333821088 1.0 0.920083347135832 12 O75844 1 +Neoplasm of the breast 0.3546030212703397 0.5280978139097748 0.5974314480587242 1.0 0.920083347135832 23 Q07864,P31749 2 +Abnormality of blood circulation 0.3057350971048502 0.5273237989694083 0.5979687501328113 1.0 0.920083347135832 64 Q02241,O75844,P20936,P07954,P31749,Q9NZ08,P22033,O76024,P23786,P40763,P46100,Q9UER7 12 +Micronodular cirrhosis 0.5009814969662707 0.525737280360634 0.5990707575356828 1.0 0.920083347135832 5 Q9NWH9 1 +Abnormal thalamic size 0.5097472924187665 0.52493853769261 0.5996259181655832 1.0 0.920083347135832 2 Q9UPT5 1 +Dilatation of the ventricular cavity 0.5097472924187665 0.52493853769261 0.5996259181655832 1.0 0.920083347135832 2 P27635 1 +Abnormal endocardium morphology 0.3784191202770738 0.5245224435496892 0.5999152138047101 1.0 0.920083347135832 14 Q9NZ08 1 +Deep palmar crease 0.3926813657135374 0.5244751411448738 0.599948105502913 1.0 0.920083347135832 13 P21281,Q9UQ13,P36507,Q02750,P98175 5 +Ankle flexion contracture 0.4189475787283316 0.5195226438732137 0.6033963264504303 1.0 0.920657220059934 11 Q5JTV8 1 +Decreased adipose tissue 0.391601755405136 0.5194069103091452 0.6034770134533014 1.0 0.920657220059934 13 O75844,P07954 2 +Axonal regeneration 0.6184935858721793 0.518383727184638 0.6041905660829481 1.0 0.920657220059934 3 P07196 1 +Flat face 0.3536737667820417 0.518190773154418 0.604325171785709 1.0 0.920657220059934 22 Q03164,P46100 2 +Neoplasm of the oral cavity 0.4316914622353346 0.5180625256308863 0.6044146453498227 1.0 0.920657220059934 10 P31749 1 +Gangrene 0.4441855490586637 0.5172104156134981 0.6050092819804918 1.0 0.920657220059934 9 Q9NZ08,P10644,P40763 3 +Episodic hyperhidrosis 0.456321624310005 0.5164839403491722 0.6055164526449559 1.0 0.920657220059934 8 Q12756 1 +Abnormality of the lens 0.2702755542099679 0.515491492684657 0.6062096129103502 1.0 0.920657220059934 175 Q9Y276,Q9H9Y6,O94761,Q9NVI7,P18077,P36507,Q71SY5,P62899,P22570,Q15800,Q9NX14,Q5SRE5,Q8N2K0,P21281,Q01968,P62244,P31749,Q06136,P39019,Q9NZ08,P23786,P07954,P61353,P42766,Q99797,Q9Y2Q9,P51608 27 +Abnormality of the larynx 0.316357918684487 0.5143747203018613 0.6069900300412301 1.0 0.9206905146596732 42 Q96HY6,Q15427,Q15165 3 +Deviation of the hand or of fingers of the hand 0.2837378653953842 0.5139727887425052 0.6072710155622119 1.0 0.9206905146596732 88 P21281,O43318,Q03164,P31749,P14923,Q96ST3,P51608,Q15427,P46100,Q71SY5,Q9Y3E5 11 +Colorectal polyposis 0.4433409546392746 0.5138660835209637 0.6073456216528155 1.0 0.9206905146596732 9 P31749 1 +Vertigo 0.3528491610294588 0.5134358447212569 0.607646477244536 1.0 0.9206905146596732 22 P14923,Q9NZ08,P40763 3 +Abnormal qt interval 0.4704652041782761 0.5120978762419575 0.6085825108209877 1.0 0.9206905146596732 7 P51608 1 +Misalignment of incisors 0.616391323153489 0.5119312770539712 0.6086991074122277 1.0 0.9206905146596732 3 P46100 1 +Widely spaced incisors 0.616391323153489 0.5119312770539712 0.6086991074122277 1.0 0.9206905146596732 3 P46100 1 +Bundle branch block 0.4170235872614199 0.5112729834990654 0.6091599199086966 1.0 0.9210509101374136 11 P04899 1 +Deviation of the hallux 0.3516821388588551 0.5110085042267014 0.6093451019036584 1.0 0.9210509101374136 23 Q15427,P31749 2 +Aplasia hypoplasia involving the metacarpal bones 0.35234502919861 0.5078450384386152 0.6115620216170079 1.0 0.9211690794020456 21 O94761,O43318 2 +Abnormality of the thymus 0.374980643624779 0.5076669266528351 0.6116869464150563 1.0 0.9211690794020456 14 P31749 1 +Diabetes insipidus 0.4160130508609349 0.5069561703375821 0.6121855721399119 1.0 0.9211690794020456 11 A5YKK6,O76024,Q01968,P31749 4 +Abnormality of pancreas physiology 0.3184768723913839 0.5066248838501464 0.6124180450835401 1.0 0.9211690794020456 37 O75489,Q9NZ08,P09601,P40763,Q9Y3E5,Q13043,Q9UNE7 7 +Abnormal delivery 0.3674110208908414 0.5064105707366785 0.612568455344644 1.0 0.9211690794020456 17 O75844,P18583,Q9Y619,Q96EY7,P50570 5 +Chronic sinusitis 0.614301191765983 0.50554512124506 0.6131760152920922 1.0 0.9215998792713482 3 Q86Y56,P57076 2 +Hemangiomatosis 0.5972836026091018 0.503778476579058 0.6144170542069565 1.0 0.922799555870658 4 P31749 1 +Nail dystrophy 0.3430912441596295 0.5035367414184645 0.6145869552046945 1.0 0.922799555870658 28 O75844,P21281,Q12756,P14923,O94761,P36507,P15924 7 +Large intestinal polyposis 0.4275000422190587 0.5008690518832581 0.6164632843880877 1.0 0.9250034076310624 10 P31749 1 +Dilated cardiomyopathy 0.3253245145681039 0.5008677494719614 0.6164642010573549 1.0 0.9250034076310624 35 P14923,Q96RL7,P00846,P35609,Q9NX14,P15924 6 +Prominent occiput 0.4396646914090926 0.4993890728367054 0.6175053156756707 1.0 0.926257973513506 9 A5YKK6,Q9Y617,P21281 3 +Color vision defect 0.4141401187306238 0.4989852900296775 0.6177897470041427 1.0 0.9263770584018308 11 Q13432 1 +Abnormal drinking behavior 0.5954196816034014 0.4980833134412093 0.6184253212799016 1.0 0.9267149590522704 4 O76024,Q9NQ48 2 +Osteoarthritis 0.3996086614860654 0.4934184831403315 0.6217169251466117 1.0 0.9284782489864352 12 O75844 1 +Morning myoclonic jerks 0.5014440433212936 0.493326476208167 0.6217819236580746 1.0 0.9284782489864352 2 Q14108 1 +Prematurely aged appearance 0.3166934793658232 0.4933107673960221 0.6217930214798659 1.0 0.9284782489864352 37 O75844,O94761 2 +Benign neoplasm of the central nervous system 0.3534598026308196 0.4900313467633309 0.6241117172598556 1.0 0.9301077814135336 20 Q01968,P31749 2 +Neuroendocrine neoplasm 0.4118417712732404 0.4892580050458227 0.624659048234343 1.0 0.9301077814135336 11 Q9UER7,P46100 2 +Stereotypy 0.306740070795912 0.4873031014063452 0.6260435501949058 1.0 0.9301077814135336 59 O95202,Q03164,Q01968,P51608,Q96F86,Q9Y5P4,Q08209,Q71SY5 8 +Abnormal hair quantity 0.2719918882061843 0.4864069977683841 0.6266786300682816 1.0 0.9301077814135336 188 Q03164,Q9Y276,Q9H9Y6,O94761,Q9Y5P4,Q9HCC0,P36507,Q71SY5,O75844,P36551,Q9UQ13,Q9H7N4,Q16851,P18074,P21281,Q96JJ3,O43318,Q01968,P31749,Q06136,O75489,P49589,Q10567,Q9Y2W2,Q96A33,Q00839,O75306,P32322,P37837,P14923,Q9BSJ2,Q8IWS0,Q15427,O15294,Q9UNE7,P15924 36 +Abnormality of the inner ear 0.4363299297611605 0.4863721363432537 0.6267033423946557 1.0 0.9301077814135336 9 Q9Y619,O15160,Q9H9Y6,P31749 4 +Trigonocephaly 0.384344463906593 0.4857215369849373 0.627164611630362 1.0 0.9301077814135336 13 Q08209,O60762 2 +Ovarian carcinoma 0.6076521765403217 0.4854273059207145 0.6273732667568641 1.0 0.9301077814135336 3 Q8WX93 1 +Peritoneal abscess 0.6076521765403217 0.4854273059207145 0.6273732667568641 1.0 0.9301077814135336 3 Q8WX93 1 +Extrahepatic cholestasis 0.6076521765403217 0.4854273059207145 0.6273732667568641 1.0 0.9301077814135336 3 Q8WX93 1 +Functional intestinal obstruction 0.6076521765403217 0.4854273059207145 0.6273732667568641 1.0 0.9301077814135336 3 Q8WX93 1 +Narrow forehead 0.3127115259543035 0.4847037571396403 0.6278865009784529 1.0 0.9301077814135336 43 Q8IZT6,P49589,Q14671,Q8TD30,Q9BSJ2,Q9UQ13,Q9NXE4,Q96A33,P36507,P46100,Q16851,Q5SRE5,P18583 13 +Enamel hypoplasia 0.4234429373723982 0.4844018960020746 0.628100673105952 1.0 0.9301077814135336 10 P51648,P18074,Q01968 3 +Abnormal bronchoalveolar lavage fluid morphology 0.4985559566786941 0.4825072276158183 0.6294456652944589 1.0 0.9305502259707086 2 P53621 1 +Fetal distress 0.3520135986015952 0.482132040287105 0.6297121502986798 1.0 0.9305502259707086 20 O75489,O43676,Q86Y39,Q9NVI7 4 +Abnormal basal ganglia mri signal intensity 0.3457234455095838 0.4820647433936247 0.6297599544887393 1.0 0.9305502259707086 24 P00846 1 +Abnormal calcium phosphate regulating hormone level 0.4351905221716503 0.4819503587097518 0.6298412109381202 1.0 0.9305502259707086 9 Q01968 1 +Microdontia 0.3462696756135598 0.4797499059689601 0.6314052368314589 1.0 0.9305609786036232 23 P21281,O94761 2 +Tetraparesis 0.3220772899903129 0.4778489976939859 0.6327576842925111 1.0 0.9315083798089168 35 O75489,P00846 2 +Motor polyneuropathy 0.4339167797984937 0.4770230970985148 0.6333456745962653 1.0 0.9317667723301616 9 P36551,P07196 2 +Muscular hypotonia of the trunk 0.2977563937584646 0.4765665122932965 0.6336708342985204 1.0 0.9319416762241912 68 O75306,P22570,Q12756,P51608,P61457,Q6IA86,Q9NVI7,Q9BSJ2,Q9Y5P4,Q9Y3C8,Q8NC96,Q5XKP0,Q16851,Q9NX14 14 +Horseshoe kidney 0.3108980542782742 0.4757094750762962 0.6342813696965499 1.0 0.93213510344783 40 O43318,P62244,P61353,P42766,P39019,P18077,Q00839,P62899,P18583 9 +Spastic tetraparesis 0.3432338394901197 0.4746003789259693 0.6350718361265564 1.0 0.9321742895535312 25 P00846 1 +11 pairs of ribs 0.4747603890242347 0.4742037514299539 0.6353546184779977 1.0 0.9321742895535312 6 P21281 1 +Abnormal blood sodium concentration 0.4329319495102758 0.4732250280935297 0.6360526435063245 1.0 0.9327120556188168 9 P36551,Q01968,Q13423,O95551,P35658,O95163 6 +Achilles tendon contracture 0.420009149317261 0.4706048138651947 0.6379229693425303 1.0 0.9330355866963138 10 Q8N2K0 1 +Abnormality of the ulna 0.3410731575139292 0.4705000473717448 0.6379978003886388 1.0 0.9330355866963138 26 O95202,Q15427,O94761 3 +Hyperreflexia 0.2723506839236114 0.4704706247836586 0.6380188165788516 1.0 0.9330355866963138 194 Q9Y276,Q8NBU5,Q10713,Q9HCC0,P00846,O14773,O60828,O75027,Q12756,O43681,Q9Y3C6,O60762,Q5XKP0,Q9BQT8,Q16851,P18074,O14949,Q8N2K0,P13073,Q01968,Q8IZT6,Q15067,O75489,P49589,Q9NZ08,Q8TD30,Q6IA86,Q7Z392,Q99986,O95140,P42695,Q06265,O75306,Q8TB37,Q9BSJ2,Q9Y3C8,P46100,P51608,Q86XL3,Q9UNE7 40 +Microvesicular hepatic steatosis 0.4320740806251364 0.4699249076891468 0.6384086682621459 1.0 0.9330355866963138 9 P54577,Q9Y276,P42704,Q9H3U1,Q00059,Q9H9J2 6 +Abnormalities of placenta or umbilical cord 0.3647811986467258 0.4678962205078626 0.6398588064155986 1.0 0.933551857719669 15 O75844 1 +Synostosis involving bones of the upper limbs 0.3420509872618332 0.4676790983788135 0.6400140904625118 1.0 0.933551857719669 25 Q15427,O94761,O43318 3 +Osteolysis 0.3445373822560413 0.4661891663064356 0.6410801032942648 1.0 0.9346240421695672 22 O75844,Q12756 2 +Epicanthus 0.2739561843315225 0.463340330823441 0.643120441446067 1.0 0.936389994989794 144 O95202,Q03164,O94761,P18077,Q9Y5P4,P36507,Q71SY5,P62899,Q15392,Q14004,Q12756,Q96ST3,Q5SRE5,P21281,P62244,Q15067,Q06265,P61353,P42766,P46100,P51608 21 +Thin upper lip vermilion 0.2797581572367933 0.4630022618959564 0.6433627458058266 1.0 0.936441006942888 89 Q96KP1,P42695,P21281,Q92643,Q03164,Q8IZT6,Q01968,P46100,P51608,Q9Y3E5 10 +Brisk reflexes 0.3483167905807052 0.4621086521076038 0.6440034059034352 1.0 0.9370716225029696 20 P49589,Q9Y3C6,Q10713,P54886,Q9BSJ2 5 +Polyhydramnios 0.3096433855529139 0.4609188501573019 0.6448568271558135 1.0 0.9377094126456276 43 O75844,Q96ST3,Q70HW3,Q9NVI7 4 +Somatic sensory dysfunction 0.281376563551846 0.4590287316828872 0.6462135336914603 1.0 0.938775802320906 93 P20936,Q9NZ08,P07196,P04792,Q96RL7,Q13217,P00846,Q71SY5,Q9UNE7,Q8N2K0,O14773 11 +Arrhinencephaly 0.4039533170587767 0.4563444661107992 0.64814229320894 1.0 0.9397847632640216 11 Q15427 1 +U shaped upper lip vermilion 0.5815042903524623 0.4563252437426668 0.6481561138403478 1.0 0.9397847632640216 4 P46100 1 +Increased blood urea nitrogen 0.4913357400721959 0.4558769839789686 0.6484784411186963 1.0 0.93995046422017 2 O95163 1 +Abnormal lower limb bone morphology 0.2774619533283574 0.4551934568010688 0.6489700674219367 1.0 0.9403613741540444 138 O95202,Q03164,O94761,Q9Y5P4,Q71SY5,Q9NX62,O75844,Q15392,Q12756,Q96HY6,Q5JRA6,P21281,P20936,O43318,P31749,Q9NWH9,Q96A33,Q15427,P46100,P51608 20 +Distal joint laxity 0.4888086642599215 0.4467020589024119 0.6550901950646559 1.0 0.9432327292794748 2 O75340 1 +Abnormal tricuspid valve physiology 0.348517013959961 0.4433569001203816 0.6575076052977893 1.0 0.9451541077745504 19 P55084,P36543,P39019,Q9NX14,P46100,Q9UER7 6 +Abnormality of the kidney 0.2653699731614646 0.4427030444454487 0.6579805400817103 1.0 0.9452324578979864 297 O95202,Q03164,Q9Y276,Q53EZ4,O94761,Q16822,P52565,P18077,Q08209,P22033,O76024,P36507,P00846,Q71SY5,P62899,Q15392,P36551,Q86Y39,Q9NQW6,Q9NX14,Q5JRA6,P21281,P20936,O43318,Q01968,Q8IZT6,P31749,P62244,O75489,P39019,Q9NZ08,Q9NWH9,P40763,O95721,P23786,Q13043,Q07864,P42695,P07954,P61353,P42766,Q8TB37,O43676,P09601,Q15427,O14745,P46100,O95470 48 +Infectious encephalitis 0.4245872918371659 0.4414621951630371 0.6588784245483317 1.0 0.9455382605432844 9 Q9NZ08 1 +Ptosis 0.2713401523164478 0.441257484374456 0.6590266015605362 1.0 0.9455382605432844 198 O95202,Q03164,Q86U42,Q5ST30,P07196,P18077,Q9Y5P4,Q08209,P36507,Q71SY5,P62899,Q14004,Q86Y39,Q9NX14,Q5JPH6,P21281,P62244,P31749,O75489,P39019,Q96A33,P40763,Q8NC96,P61353,P42766,Q8TB37,O43676,Q9Y2Q9,Q8IWS0,Q15427,P46100,O95470,P51608 33 +Abnormality of the nasal skeleton 0.5762636791139079 0.4409629451670363 0.6592398230879473 1.0 0.9455382605432844 4 P22314,P10644 2 +Abnormal heart sound 0.5760911727506961 0.4404607889814077 0.6596034056354745 1.0 0.9457595006858376 4 P10253 1 +Carcinoid tumor 0.5758778866525532 0.4398402398467185 0.6600528208363032 1.0 0.9459041127732376 4 P46100 1 +Synostosis of metacarpals metatarsals 0.5921410526696045 0.4397276147946815 0.6601343995097939 1.0 0.9459041127732376 3 O60828 1 +Hydrops fetalis 0.3062881617575574 0.4385533277056832 0.6609852215037535 1.0 0.9462392999854112 41 P20936,P55084,P62244,P61353,P42766,P37837,P10619,P39019,Q9H0R6,P18077,P62899 11 +Abnormality of the spinal cord 0.3000317320468374 0.4370038863894613 0.6621085295412681 1.0 0.9466320749924316 60 P21281,P20936,O43318,P31749,Q96ST3,O94761,P07196,Q13217 8 +Cortical dysplasia 0.3306365984939922 0.4360104893656918 0.6628291191357985 1.0 0.9466320749924316 29 Q8IZT6,Q96ST3,Q96F86,O95721,Q71SY5 5 +Abnormal pyramidal sign 0.2833482771698982 0.4356590300285461 0.663084135239534 1.0 0.9466320749924316 107 O95140,O75027,Q12756,P51648,Q15067,P49589,Q9NZ08,P07196,Q8TD30,Q13217,P00846,P51608,Q9UNE7,Q8N2K0,O14773 15 +Abnormal cellular phenotype 0.2629313109855541 0.4355238443187736 0.6631822353171479 1.0 0.9466320749924316 168 Q9Y3D9,P00846,P35609,O14773,O75844,Q92643,P22570,Q86Y39,P26038,Q9NX14,Q9Y584,Q5JPH6,Q9UBX3,Q01968,P31749,O75489,Q70HW3,P40763,P23786,Q13043,P13051,O43676,P09601,P51608,P15924 25 +Triangular shaped phalanges of the hand 0.3042323270248706 0.4314757046395596 0.6661225143993028 1.0 0.9499815404217328 53 P21281,O43318,P62244,P61353,P42766,P18077,Q15427,P62899 8 +Partial agenesis of the corpus callosum 0.4322687525975421 0.4274688230934445 0.6690378885307422 1.0 0.9520356473643758 8 Q15392,P18074,P40925,P82663 4 +Dysphasia 0.3450571217381752 0.4255374228220136 0.6704449469987264 1.0 0.9526520831215068 19 Q9NX14,Q01968,P46100 3 +Decreased activity of mitochondrial complex ii 0.4706467733819733 0.4245706687251698 0.6711496788042668 1.0 0.9526520831215068 5 Q5T440 1 +Male hypogonadism 0.4599898904236834 0.4243296541199397 0.6713254155671318 1.0 0.9526520831215068 6 Q8N5K1,O76024,P51608,P09884 4 +Facial edema 0.3314629019342745 0.4237281669279066 0.6717640707387347 1.0 0.9526520831215068 27 O94761,Q9NQW6,Q12756 3 +Delayed eruption of permanent teeth 0.58593827583218 0.4219648653295457 0.6730506628039921 1.0 0.9526716086035516 3 P21281 1 +Aplasia hypoplasia of the eyelid 0.3699624449346566 0.4211198814605351 0.6736675444438649 1.0 0.9528828792262508 13 Q15427 1 +Chordee 0.4586742424591027 0.4199868008617162 0.6744950960282772 1.0 0.9528828792262508 6 Q9NX14 1 +Mucosal telangiectasiae 0.4443723222148428 0.41957653372885 0.6747948340429182 1.0 0.9528828792262508 7 P18074,P31749 2 +Ankle clonus 0.4069599024441225 0.4194244216289484 0.674905979088978 1.0 0.9528828792262508 10 Q9UNE7,Q12756 2 +Pleural effusion 0.3814757417522973 0.4155156654524679 0.6777644496503277 1.0 0.9551278176918842 12 P20936,Q9NZ08 2 +High forehead 0.2873592410808277 0.4147464997884185 0.6783274881975161 1.0 0.9552101125731948 74 O95202,P21281,Q03164,P49589,Q96ST3,Q9NVI7,Q08209,P36507,Q8NC96,Q71SY5,Q9NX62 11 +Spastic tetraplegia 0.3160084305057401 0.4145694499550048 0.678457116256614 1.0 0.9552101125731948 34 Q96KP1,Q13057,Q9Y3C6,Q8NBJ5,O00139,P51608,Q86XL3 7 +Microcornea 0.3333398963397617 0.4117339793196971 0.680534416586194 1.0 0.956346654474782 24 O94761 1 +Adducted thumb 0.332428437359504 0.4066913741133999 0.6842346766786231 1.0 0.958912027212506 24 Q06265,Q8NBU5,P54886,Q9NXE4,Q71SY5,Q86XL3,Q9UNE7 7 +Oral pharyngeal dysphagia 0.3793399192417958 0.4066431311358088 0.6842701141507568 1.0 0.958912027212506 12 Q08209,Q06265 2 +Slowly progressive 0.3013905245808529 0.4053464416809612 0.6852228735716124 1.0 0.9599494396268357 52 Q12756,P07196,O75190,P04792,Q5JTV8,P51608,Q8N2K0,O14773 8 +Anencephaly 0.3514148572716962 0.4047748598408674 0.6856430098982425 1.0 0.9599548043349846 15 P21281,Q15427 2 +Neurogenic bladder 0.439761298340619 0.4039287055104312 0.6862651468243672 1.0 0.9599548043349846 7 P20936,O43318 2 +Muscle abnormality related to mitochondrial dysfunction 0.3170664981404527 0.4033447381223853 0.6866946342536528 1.0 0.9599548043349846 33 O75489,O43676,Q86Y39,P00846 4 +Neurodegeneration 0.3294845463888615 0.4032441711794302 0.6867686079106452 1.0 0.9599548043349846 26 Q15165 1 +Abnormality of toe 0.2717029762951725 0.4032111244974453 0.686792916592069 1.0 0.9599548043349846 141 O95202,Q03164,P07196,Q9Y5P4,Q71SY5,Q9NX62,O75844,Q12756,Q96ST3,P04792,O60762,Q5JRA6,P21281,O00764,P31749,Q96A33,P23786,O95140,P14923,Q9Y2Q9,Q15427,P51608,Q9Y3E5,P15924 24 +Persistence of primary teeth 0.4392369521012345 0.4021637908495512 0.6875634883987027 1.0 0.9599548043349846 7 O75844 1 +Vascular neoplasm 0.3167317559779753 0.401194216029586 0.6882771388290321 1.0 0.959982436965128 33 O95202,P21281,P20936,P31749,O94761,O60762,P36507 7 +Aplasia hypoplasia of metatarsal bones 0.4528412185364395 0.400939770225963 0.688464468336744 1.0 0.959982436965128 6 O43318,P10644,Q9NQ48 3 +Advanced eruption of teeth 0.4017359291058674 0.3995292983284596 0.6895032401474168 1.0 0.9605845325272984 10 O75844,P14923 2 +Meningocele 0.412510959495223 0.396909703278772 0.6914340485294126 1.0 0.9614955467084906 9 Q96ST3 1 +Intestinal atresia 0.4221348150968729 0.3918029066473038 0.6952038472392594 1.0 0.9641203952453402 8 Q9Y2W2,Q96ST3 2 +Pancytopenia 0.3198305515746423 0.3917510079425295 0.6952421973681537 1.0 0.9641203952453402 31 P00374,O94761 2 +Abnormality of the synovia 0.2858038266417207 0.3865797230786864 0.6990673716940052 1.0 0.965096505422713 72 O75844,O43318,Q01968,P31749,O94761,Q15427,Q96A33,Q9Y3E5,Q9Y584 9 +Celiac disease 0.5726110412448726 0.3848600666437973 0.7003410934705465 1.0 0.965096505422713 3 Q13043 1 +Glossoptosis 0.4336222208908709 0.3834555161933376 0.701382047116683 1.0 0.965096505422713 7 O15160,P98175,Q9H9Y6 3 +Relative macrocephaly 0.325922306176131 0.3832216838594935 0.7015554016357415 1.0 0.965096505422713 26 O75844,Q07864 2 +Abnormality of the musculature of the upper limbs 0.2873130073853759 0.38096252436325 0.7032310566087805 1.0 0.965096505422713 68 O43318,P62244,P61353,P42766,P39019,P07196,O75190,P18077,P04792,Q9BQT8,P62899 11 +Eyelid coloboma 0.3966391149364614 0.3804685516588991 0.7035976365944794 1.0 0.965096505422713 10 Q15427 1 +Atrophy degeneration involving the spinal cord 0.4319168128426622 0.3778434402269504 0.7055469010756501 1.0 0.9656652223749732 7 Q13217 1 +Male pseudohermaphroditism 0.5534809133332372 0.3767036466730967 0.7063938525226501 1.0 0.9661904617069026 4 Q9NX14 1 +Abnormality of the nasal bone 0.5686070258803846 0.3740074695598523 0.7083987589205929 1.0 0.9673901995167716 3 P10644 1 +Rhabdomyolysis 0.3589542800583731 0.3738442721466711 0.7085201793273568 1.0 0.9673901995167716 13 P23786,Q9Y276 2 +Recurrent otitis media 0.3308837096057017 0.3712881425527267 0.7104229286659489 1.0 0.967860926008582 20 Q13432 1 +Unusual infection by anatomical site 0.3703306388218843 0.3699895097097238 0.7113903066940992 1.0 0.9683824662982644 12 Q9NZ08 1 +Peripheral visual field loss 0.4664259927797768 0.3690008172439933 0.7121271156225653 1.0 0.9688016586518368 2 P10515 1 +Radial deviation of the hand or of fingers of the hand 0.3698556581241086 0.3680929648967193 0.7128039164050626 1.0 0.9689912017871966 12 Q96ST3,Q15427 2 +Abnormality of the achilles tendon 0.3812461340287004 0.366156087584868 0.7142486072440057 1.0 0.9689912017871966 11 Q8N2K0 1 +Peripheral axonal neuropathy 0.2966548930053522 0.3660255674977271 0.7143459973417008 1.0 0.9689912017871966 51 Q13057,Q15067,Q12756,P07196,Q9NVI7,P04792,Q96RL7,P40763,P00846,O95140 10 +Uveitis 0.4145674898429499 0.3659649363362806 0.7143912400430601 1.0 0.9689912017871966 8 P29401,Q9UNE7,Q13043,P01889 4 +Sparse scalp hair 0.3154723492105806 0.3653634471138078 0.7148401229651895 1.0 0.9689912017871966 31 Q71SY5,O94761,Q01968 3 +Osteopenia 0.2895152188772397 0.3639703257874548 0.7158801683967351 1.0 0.969409695413752 62 O75844,P57678,O94761,Q5JRA6,O14745,P40763,P18074,Q13043,Q07864 9 +Abnormal serum iron concentration 0.5484728884575221 0.3631651210746872 0.7164815408263407 1.0 0.969409695413752 4 Q9Y276 1 +Abnormal electroretinogram 0.3183059883750727 0.3629385145674992 0.7166508151133093 1.0 0.969409695413752 29 P00846 1 +Congenital sensorineural hearing impairment 0.4407159818611623 0.3624804507861702 0.7169930297012144 1.0 0.969536810254116 6 O43318 1 +Focal dystonia 0.32532945306783 0.3616446025824497 0.717617629428076 1.0 0.9698463804235858 21 P04350,Q13057,O15160,Q9H9Y6,Q96RL7 5 +Deviation of the thumb 0.3675721612174114 0.3590271307192289 0.7195747931504268 1.0 0.9706152785422484 12 Q96ST3 1 +Abnormal levels of alpha fetoprotein 0.4260740115318008 0.3588726105456831 0.719690390242703 1.0 0.9706152785422484 7 Q9NWH9 1 +Aplasia hypoplasia of the thyroid gland 0.4489452415134535 0.3573550501400583 0.7208260228456993 1.0 0.971749453813149 5 Q9H9Y6 1 +Paranoia 0.4486570402985539 0.3564950941944588 0.7214698253629108 1.0 0.971749453813149 5 Q96RL7,P36551 2 +Eeg with multifocal slow activity 0.4002608340063741 0.353588157306798 0.7236475508389462 1.0 0.97285562612352 9 Q8NC96 1 +Generalized muscle weakness 0.3187634643466743 0.3516358293001688 0.7251113912627034 1.0 0.97285562612352 27 Q15165 1 +Renal cell carcinoma 0.329653116644881 0.3491586416982922 0.7269702137147005 1.0 0.97285562612352 19 P31749 1 +Abnormality of the cerebrospinal fluid 0.2754328466024809 0.3489938781703987 0.7270939054927579 1.0 0.97285562612352 122 O95202,Q10713,O94761,Q14738,Q9C0B1,P00846,P36507,Q15392,P57076,P51970,Q12756,Q86Y39,Q9UQ13,Q9NX14,P18074,P13073,P20936,P31749,O75489,Q00839,P23786,O95140,O75306,Q8TB37,P32322,O43676,Q15427,P51608 28 +Cerebellar dysplasia 0.4599277978339282 0.3477274044214619 0.7280449137663634 1.0 0.973455732582548 2 P60953 1 +Supraventricular arrhythmia 0.3382349022313583 0.3456965006801678 0.7295708143675088 1.0 0.9749248120638928 15 P00846 1 +Perimembranous ventricular septal defect 0.4438764895871876 0.3423627532930003 0.7320779152525954 1.0 0.9762665962137146 5 P46100 1 +Abnormality of iron homeostasis 0.443712034381481 0.3418810725148176 0.7324403942541566 1.0 0.9762665962137146 5 Q9Y276 1 +Coma 0.3114606566016378 0.3415961210961709 0.7326548567149174 1.0 0.9762665962137146 31 P55084,Q9Y619,P31751,P22033,Q9HCC0,P40763,Q16836,P23786 8 +Abnormality of neutrophils 0.2717983146471593 0.3407610534162035 0.7332834723411876 1.0 0.9764145971227484 82 P62244,P61353,P42766,Q9Y3C6,P39019,O94761,P18077,P26038,P46100,P35609,Q13043,P62899,P15924 13 +Memory impairment 0.3107767678259571 0.3375962189898613 0.73566749187927 1.0 0.9774275330455108 31 Q9NZ08,P31749 2 +Small face 0.3107654786995341 0.3375303205567488 0.7357171592816967 1.0 0.9774275330455108 31 Q96ST3,O94761,Q9H9Y6 3 +Upslanted palpebral fissure 0.2766518165572134 0.3375199062061144 0.7357250086398925 1.0 0.9774275330455108 77 Q96KP1,P42695,O43318,Q01968,Q8IZT6,Q96ST3,Q9NVI7,Q9Y5P4,P46100,P51608 10 +Hematological neoplasm 0.2797497614113545 0.3374537000935696 0.7357749092270434 1.0 0.9774275330455108 73 P62244,P61353,P42766,P39019,O94761,Q13951,P18077,P46100,P62899,Q07864 10 +Shawl scrotum 0.4312886760140659 0.3337047811284809 0.7386023413898433 1.0 0.978759874623014 6 P46100 1 +Visual loss 0.2927803483228324 0.3332518154917703 0.7389442081317177 1.0 0.978759874623014 46 Q96JJ3,Q12756,P31749,P00846,Q9NX14,O14773 6 +Aplasia hypoplasia affecting the eye 0.2657527308647228 0.3321750576911444 0.739757076556619 1.0 0.9792623709003238 86 Q96KP1,O95202,Q01968,Q9H9Y6,Q96ST3,O94761,P07196,Q9NVI7,O95721,P36507,Q71SY5,Q9NX14,Q5SRE5 13 +Macroorchidism 0.439806605387686 0.3305314633048819 0.7409984229579036 1.0 0.9803106069859177 5 P31749 1 +Aplasia hypoplasia involving bones of the upper limbs 0.2741156879612182 0.3298732083471344 0.7414957680672045 1.0 0.9803106069859177 120 O95202,O75844,P21281,O43318,Q03164,P61353,P42766,P62244,Q96ST3,O94761,P39019,Q9Y2Q9,P18077,Q15427,O60762,P51608,Q9NX62,P62899 18 +Open bite 0.3339315320501849 0.3271598542973975 0.7435469831571899 1.0 0.981472278107184 15 P21281,Q01968 2 +Chest pain 0.3319132762375185 0.3255785994507752 0.7447432058745158 1.0 0.981472278107184 16 P20936,P07954,P01889,P40926,P27797,Q02978,Q9BTV4,P50336,P10644 9 +Flexion contracture of digit 0.2873027198761494 0.3253684023893964 0.7449022668502732 1.0 0.981472278107184 59 O75844,O43318,Q14004,Q01968,P10412,P14923,P07196,Q8IWS0,O60762,Q71SY5,Q5SRE5,P15924 12 +Abnormality of lower limb joint 0.2663041079538558 0.3244365560523607 0.7456075474455823 1.0 0.9815428028435724 140 O95202,O94761,P36507,Q5JTV8,Q9NX62,O75844,Q12756,O60762,Q96HY6,Q5JRA6,Q9Y584,O43318,Q01968,P62244,P31749,P49589,Q96A33,P23786,O95140,P14923,Q8IWS0,Q15427,P46100,Q9Y3E5,Q9UNE7,P15924 26 +Abnormality of the tarsal bones 0.3176953352760582 0.3235555928869293 0.7462745125353625 1.0 0.9818582526768648 22 O75844,O43318,Q9NXE4,P18074,Q5SRE5 5 +Aplasia hypoplasia of the ear 0.290979107233133 0.3235459489315015 0.7462818148942791 1.0 0.9818582526768648 51 O95202,P62244,P61353,Q9H9Y6,P42766,P18077,Q15427,P46100,P62899,Q07864 10 +Aganglionic megacolon 0.3463984669266412 0.3225178448683004 0.7470604211536351 1.0 0.981953207560712 13 Q15427 1 +Lactic acidosis 0.2773909293365132 0.3224279091099112 0.7471285438126043 1.0 0.981953207560712 74 P55084,Q9Y276,Q10713,Q5JTZ9,Q6P4A7,Q9Y606,P51970,Q86Y39,Q5XKP0,Q9NX14,Q5JPH6,Q4G0N4,O75489,Q70HW3,Q16836,O75306,P07954,Q8TB37,Q99797,Q9Y2Z4,Q9H0R6,O43676 22 +Myelofibrosis 0.5486235895353591 0.3220158333507432 0.7474406996018788 1.0 0.981953207560712 3 Q9UQ13 1 +Prolonged bleeding time 0.4004117339087524 0.3196039761232577 0.7492685598455269 1.0 0.9823550067852844 8 P27797,Q15149,Q14692,P36507 4 +Large face 0.2900164786128399 0.318446720551089 0.7501461034147998 1.0 0.982744934787852 52 Q92643,Q01968,P31749,Q96ST3,O94761,Q9NVI7,P36507 7 +Abnormal epiphysis morphology of the phalanges of the hand 0.4261134310686442 0.3183512386981588 0.7502185214881145 1.0 0.982744934787852 6 Q5JRA6,P10644,Q9Y2Q9 3 +Cone shaped epiphyses of the phalanges of the hand 0.4261134310686442 0.3183512386981588 0.7502185214881145 1.0 0.982744934787852 6 Q5JRA6,P10644,Q9Y2Q9 3 +Dry skin 0.3125340552606049 0.3179213696335888 0.7505445823144257 1.0 0.982783893612819 27 Q96KP1,P51648,Q06136 3 +Abnormality of the pinna 0.2637485991079638 0.316995663517554 0.7512468927171045 1.0 0.982783893612819 200 O95202,Q9H9Y6,O94761,P18077,P36507,P62899,O75844,Q15392,Q92643,Q12756,Q96ST3,Q96TA2,Q9NX14,Q5SRE5,Q96KP1,P21281,O43318,Q01968,P62244,P31749,Q06136,P39019,Q96A33,O95721,Q07864,P61353,P42766,P14923,Q15427,P46100,P51608,P15924 32 +Increased circulating cortisol level 0.5465667319954859 0.3168783716646725 0.7513358938775292 1.0 0.982783893612819 3 P17612 1 +Synostosis of joints 0.3104652769551324 0.3131185605576589 0.7541905883389346 1.0 0.9848425596139576 28 Q15427,O94761,O43318 3 +Abnormality of muscle size 0.2563094212002554 0.3113618894865421 0.7555255227140276 1.0 0.9848425596139576 173 Q13057,P07196,Q15165,Q9NVI7,Q9HCC0,Q6P4A7,P35609,Q71SY5,P04792,Q9BQT8,Q8N2K0,P21281,P20936,O43318,P31749,Q96A33,Q13043,Q96RL7,P46100,P51608,Q9UNE7 21 +Abnormality of the anus 0.287495832169053 0.3102386600810591 0.756379473365951 1.0 0.985387099385054 39 Q96ST3,O94761 2 +Glomerulopathy 0.3767764871239142 0.3097659258546872 0.7567389651307095 1.0 0.985571243718808 10 Q9NZ08 1 +Abnormal nephron morphology 0.2859075116740604 0.3091204443320555 0.757229907955344 1.0 0.9856003202377648 58 P07954,Q01968,Q9Y276,Q9NZ08,Q9NQW6,P52565,O95470,P00846,P23786 9 +Difficulty running 0.3763296411679306 0.3082450957521127 0.757895840430213 1.0 0.9856572847045776 10 P07196 1 +Poor eye contact 0.3015646867460576 0.3076177664026023 0.7583731997176222 1.0 0.9857967503937436 33 Q8TB37,O75489,P51608,O43676,Q86Y39,Q5XKP0,Q16851,Q9NX14 8 +Scrotal hypoplasia 0.3231940897004853 0.3065588372363825 0.7591791890026629 1.0 0.9862063840147204 18 O15160,P46977,Q9H9Y6,Q9H0U9,Q8TCJ2,Q8IWS0,P46100,P18074 8 +Spinal canal stenosis 0.4084794745322742 0.304281752654944 0.7609132457525762 1.0 0.9867411148995808 7 P31749 1 +Abnormal atrioventricular valve physiology 0.2873018330340454 0.3029444579430076 0.7619321897786289 1.0 0.9877789478966555 41 O75844,O43318,Q9NZ08,Q9NX14,P46100,Q9UER7 6 +Abnormal size of the palpebral fissures 0.2748804823794755 0.3001802658407374 0.764039656950418 1.0 0.9895722013728422 74 O94761,Q03164 2 +Reduced visual acuity 0.2700399430220928 0.3000638536343626 0.7641284500923955 1.0 0.9895722013728422 102 P22570,O43318,P31749,O75489,Q9NZ08,O43676,Q86Y39,P00846,Q96TA2,Q71SY5,Q9NX14 11 +Heat intolerance 0.4278879157346054 0.2969852142936418 0.7664777974415613 1.0 0.990262135785237 5 Q02750,P36507 2 +Aplasia hypoplasia of the proximal phalanges of the hand 0.5376718446140946 0.2951419720132317 0.7678854279811622 1.0 0.9905824133632952 3 Q08AM6 1 +Abnormality of the palpebral fissures 0.2615952181426857 0.2939407895571311 0.768803148602867 1.0 0.9909993225072048 197 O95202,Q03164,Q9H9Y6,O94761,Q9NVI7,Q9Y5P4,Q08209,P36507,Q71SY5,O75844,Q15392,Q14004,Q96ST3,Q96KP1,P21281,O43318,Q01968,Q8IZT6,P31749,Q8NC96,P42695,Q15427,P46100,P51608 24 +Impaired social interactions 0.2846688089741069 0.2914501302109105 0.7707070793587687 1.0 0.9920383431746204 39 Q15067,Q8TB37,O75489,P51608,O43676,Q86Y39,Q5XKP0,Q16851,Q9NX14 9 +Decreased activity of mitochondrial complex iii 0.3808885233968154 0.2893740463241562 0.7722951538408076 1.0 0.9925369234683136 9 Q9Y584 1 +Cerebellar vermis atrophy 0.3704472426993367 0.2885282122921714 0.7729424380064847 1.0 0.9925684827565376 10 Q10713,Q14671,Q12756 3 +Abnormality of globe size 0.2853548964803743 0.2867581453592221 0.7742975127167557 1.0 0.9925684827565376 53 Q01968,Q9H9Y6,P31749,Q96ST3,O94761,Q71SY5,Q9NX14 7 +Chronic lung disease 0.4150397686189387 0.2866081771567453 0.774412352540121 1.0 0.9925684827565376 6 Q8N3U4,P50454,P50851,P12955,Q96J02 5 +Abnormality of the frontal hairline 0.2765655629785842 0.2831356781492036 0.7770728328868295 1.0 0.9942685984384998 65 O95202,Q92643,P21281,P36551,O15160,O43318,P62244,Q9H9Y6,P61353,P42766,Q96ST3,P39019,P18077,Q9NXE4,Q16851,P62899,P29372 17 +Tented upper lip vermilion 0.3175128533225707 0.2816747151872549 0.7781929441239628 1.0 0.994539434493653 18 P51608,P46100,Q71SY5 3 +Neonatal hypoglycemia 0.4003446877563956 0.2804156760898686 0.7791586115286948 1.0 0.9952611271944144 7 Q16836,P54577,P31751 3 +Red eye 0.3189297905343546 0.2786050402597883 0.7805479442457322 1.0 0.9961393887246288 17 P01889,Q10567,Q9NZ08,P02786,P18074,P34897 6 +Hypoglycemic coma 0.3767195436948782 0.2762998882399896 0.7823177417479226 1.0 0.9961393887246288 9 Q16836,P31751 2 +Abnormal cry 0.356018625896399 0.275285146808834 0.7830971749275628 1.0 0.9961393887246288 11 Q06265,P51608 2 +Recurrent pancreatitis 0.4361010830324842 0.2751964647981241 0.783165302836681 1.0 0.9961393887246288 2 P00403 1 +Ulnar deviation of finger 0.4191143504698159 0.2733878699386427 0.7845550761471283 1.0 0.9961393887246288 5 Q9Y3E5 1 +Hyperkalemia 0.5283495846876151 0.2732213014170299 0.7846831065443458 1.0 0.9961393887246288 3 Q13423,Q13618 2 +Aplasia hypoplasia of the spleen 0.5125956329056673 0.2730656903185208 0.7848027199470682 1.0 0.9961393887246288 4 P08865,P57076 2 +Type ii diabetes mellitus 0.2955921883848414 0.2730346032993405 0.7848266161792767 1.0 0.9961393887246288 33 P49589,Q9Y6M1,P31751,Q9UNE7,P17096 5 +Limitation of joint mobility 0.261094343914369 0.2727141831723373 0.7850729312416254 1.0 0.9961393887246288 85 O75844,O43318,Q01968,Q8NBU5,P31749,P51648,Q12756,O94761,Q15427,P46100,P51608,P23786,O95140 13 +Colitis 0.3654130466407222 0.2721135326490205 0.7855347244785884 1.0 0.9961393887246288 10 O43318 1 +Dyskinesia 0.2815666455735391 0.2720287638226156 0.7855999026849168 1.0 0.9961393887246288 57 Q12756,Q96F86,Q08209,Q96RL7,P00846,Q8NC96,Q71SY5 7 +Psychotic episodes 0.4346570397111844 0.2710915089833056 0.7863206519944406 1.0 0.9961393887246288 2 Q5JRX3 1 +Abnormal csf metabolite level 0.2837988147602733 0.2710070313400717 0.7863856243393152 1.0 0.9961393887246288 50 P13073,P51970,Q8TB37,O75489,O43676,Q86Y39,P00846,P51608,Q9NX14 9 +Respiratory arrest 0.4092803555060087 0.2707204780473766 0.7866060255541318 1.0 0.9961393887246288 6 P23786 1 +Parkinsonism 0.305269691563804 0.2695377182479341 0.7875159208453248 1.0 0.9961393887246288 25 Q96RL7,Q13057,P61457,Q9UNE7 4 +Central hypoventilation 0.4168859495841719 0.2675481182538118 0.7890471709373263 1.0 0.9961393887246288 5 P51608 1 +Myopia 0.2617983926584048 0.2675199923956762 0.7890688232178202 1.0 0.9961393887246288 84 Q13868,O94761,Q14738,Q9NVI7,P30533,P36507,O15160,Q9UQ13,Q96TA2,P18074,Q9NX14,P21281,Q15067,P31749,Q10567,Q7Z392,P51648,P46100,P18583 19 +Gastrointestinal atresia 0.3536642803911883 0.2673720931898465 0.7891826839385725 1.0 0.9961393887246288 11 Q9Y2W2,Q96ST3,P18583 3 +Episodic pain 0.3316550446996477 0.2661846741599835 0.790096985623469 1.0 0.9961393887246288 13 P23786,Q9UER7,P46100 3 +Abnormal biliary tract morphology 0.3056163369494192 0.2657507789343448 0.7904311531065549 1.0 0.9961393887246288 21 Q9Y276,Q10713,P09601,Q5XKP0,Q13043 5 +Oral cleft 0.2609622499909144 0.2652625810167899 0.7908071882599008 1.0 0.9961393887246288 141 O95202,Q9H9Y6,O94761,P18077,Q08209,P36507,Q71SY5,Q9NX62,P62899,O75844,Q15392,Q5SRE5,Q5JPH6,P21281,O43318,P62244,P49589,P39019,P61353,P42766,P14923,Q15427,P15924 23 +Proximal muscle weakness in upper limbs 0.3417025915456535 0.2628054731684585 0.7927005168077059 1.0 0.9961393887246288 12 P07196,O95140 2 +Lower limb muscle weakness 0.2802216190221487 0.262650714271802 0.7928198075852335 1.0 0.9961393887246288 39 P20936,Q12756,P31749,P07196,P04792,P00846 6 +Insomnia 0.3520535643879323 0.2620178258416265 0.7933076991355286 1.0 0.9961393887246288 11 Q9UNE7 1 +Abnormality of the tongue 0.2645342584828658 0.2615277031146937 0.7936855886906822 1.0 0.9961393887246288 81 O75844,P21281,Q71SY5,P31749,Q9H9Y6,P07196,Q96RL7,Q96A33,P46100,Q9BQT8 10 +Atrophy degeneration affecting the brainstem 0.3711263811235138 0.2591983850002523 0.7954821771196092 1.0 0.996945485777086 9 Q13217 1 +Tooth malposition 0.2661602529993161 0.2585564422842257 0.7959774946071929 1.0 0.9970131191115325 79 P21281,O75844,O43318,Q01968,Q9H9Y6,Q96ST3,Q9Y5P4,Q96A33,P46100,P51608 10 +Pallor 0.2816719155636156 0.2560384899954917 0.7979211169032223 1.0 0.9986170654207088 47 P07954,P22570,P62244,P61353,P42766,P39019,P00374,P18077,P62899 9 +Fibrosarcoma 0.4281588447653376 0.25304904612697 0.8002303128919959 1.0 0.9991537033408352 2 P35222 1 +Oral cavity bleeding 0.4025947473138097 0.2528325924362456 0.8003975806285271 1.0 0.9991537033408352 6 Q02241,P40763 2 +Abnormal c peptide level 0.519292177478093 0.2527941322881411 0.8004273022251396 1.0 0.9991537033408352 3 A5YKK6 1 +Laryngeal cleft 0.4277978339350121 0.2520675165651999 0.8009888774434575 1.0 0.9991537033408352 2 Q69YQ0 1 +Narrow face 0.2996190150515086 0.2519010382851348 0.8011175570261129 1.0 0.9991537033408352 27 Q96ST3,O94761 2 +Optic disc pallor 0.2795824775473546 0.2497600764409167 0.802772895778493 1.0 0.9991537033408352 42 O75489,O43676,Q86Y39,P00846 4 +Spastic gait 0.311180830560901 0.2470021092779052 0.8049065916767031 1.0 1.0 17 Q12756,Q9Y619,P54886,Q9NVI7,P51608 5 +Abnormality of the amniotic fluid 0.2677778469797381 0.2450181635981601 0.8064423674282664 1.0 1.0 75 P21281,O75844,Q06265,P14923,Q96ST3,Q70HW3,Q9NVI7,Q9Y5P4 8 +Hyperammonemia 0.2882560514483964 0.244294259497898 0.8070029290747744 1.0 1.0 34 P55084,Q9Y619,P22033,Q9HCC0,Q16836,P51608,P23786 7 +Palpitations 0.3119286089849122 0.2437667919980426 0.8074114407274882 1.0 1.0 16 P14923,Q9UER7,P46100 3 +Abnormality of the cheek 0.2793217232697785 0.2405880498209204 0.8098744130362652 1.0 1.0 50 O95202,P04350,O15160,Q96JJ3,O43318,Q01968,Q9H9Y6,Q12756,P10412,Q9Y2W2,O60762,Q15427,P36507,Q00839,P18583 15 +Abnormal pons morphology 0.3052758936692105 0.2397675491390661 0.8105104652612938 1.0 1.0 19 Q9Y3C6,O60762,Q9UNE7 3 +Small for gestational age 0.2683529566379176 0.2395976364406223 0.8106421972592466 1.0 1.0 73 O95202,P62244,P61353,P42766,P49589,Q96ST3,O94761,P18077,Q9Y584,P51608,Q5SRE5,P62899 12 +Dental crowding 0.2990538844141412 0.2372471426701902 0.8124650655299892 1.0 1.0 24 O75844,Q96A33,Q01968 3 +Aplasia hypoplasia of the phalanges of the thumb 0.3634637677407515 0.2366114960555987 0.8129582008660763 1.0 1.0 9 A5YKK6,O43318 2 +Thin skin 0.2991967280137603 0.2361089384375903 0.8133481381272254 1.0 1.0 22 O75844,P32322,Q9Y619,P54886,P17612,P18074 6 +Protruding tongue 0.3427700183035485 0.2321229109167335 0.8164425504689525 1.0 1.0 11 Q96RL7,Q10713,P46100 3 +Alkalosis 0.4940981240250601 0.2317466541541639 0.8167347928586439 1.0 1.0 4 Q9Y619,P01889 2 +Finger clinodactyly 0.2698212572729936 0.2317339353716694 0.8167446721096792 1.0 1.0 66 P21281,O43318,Q03164,P31749,P14923,O15294,P46100,P51608,Q5JRA6,P15924 10 +Cupped ear 0.3323107973906869 0.231097514709737 0.8172390458424963 1.0 1.0 12 Q15392 1 +Craniofacial dysostosis 0.4021931928627563 0.2306628433413638 0.8175767418423106 1.0 1.0 5 O15160 1 +Weight loss 0.2693948844747998 0.228499650888811 0.8192578274940612 1.0 1.0 66 O75844,P31749,Q06136,Q9NZ08,Q96RL7,P40763,P46100,P51608,Q9UER7,Q13043,Q9UNE7 11 +Muscle spasm 0.2773446589091649 0.2275119327355751 0.8200256915256836 1.0 1.0 50 P07196,Q15165,P00846 3 +Abnormal size of the clitoris 0.3084561607634742 0.2260163492401256 0.8211887044655835 1.0 1.0 15 P22570 1 +Abnormal circulating amino acid concentration 0.2769486918719871 0.2252283695889031 0.8218016206304077 1.0 1.0 47 Q9HCC0 1 +Hypermetropia 0.2755733734446197 0.2245875548056176 0.8223001474063161 1.0 1.0 42 P68371,Q96ST3,Q9UQ13,Q96A33,Q96TA2,Q71SY5,O15294,P18583 8 +Hypoplasia of the vagina 0.41732851985559 0.2245749052652978 0.8223099889360432 1.0 1.0 2 P51809 1 +Urogenital sinus anomaly 0.41732851985559 0.2245749052652978 0.8223099889360432 1.0 1.0 2 P51809 1 +Gonadoblastoma 0.41732851985559 0.2245749052652978 0.8223099889360432 1.0 1.0 2 P51809 1 +Ovarian gonadoblastoma 0.41732851985559 0.2245749052652978 0.8223099889360432 1.0 1.0 2 P51809 1 +Female external genitalia in individual with 46 xy karyotype 0.41732851985559 0.2245749052652978 0.8223099889360432 1.0 1.0 2 P51809 1 +Abnormal sex determination 0.41732851985559 0.2245749052652978 0.8223099889360432 1.0 1.0 2 P51809 1 +Abnormal mitral valve physiology 0.2881569035144923 0.222361896091892 0.8240321718061829 1.0 1.0 32 O75844,Q9NX14,Q9NZ08 3 +Wide nasal bridge 0.2588410863739002 0.2205751620014036 0.825423242576719 1.0 1.0 138 O95202,Q03164,Q9H9Y6,Q9NVI7,P18077,Q9NX62,P62899,Q14004,Q96ST3,Q9NX14,Q5SRE5,Q96KP1,P21281,O43318,P62244,Q15067,P39019,P40763,P61353,P42766,P46100,P51608 22 +Abnormality of cranial sutures 0.264126195166362 0.2203915339313394 0.825566238274765 1.0 1.0 76 O75844,P21281,O43318,Q12756,P31749,P39019,O94761,Q08209,Q5SRE5,Q9NX62 10 +Paraplegia 0.2757555863026618 0.2198098593469128 0.8260192407699853 1.0 1.0 45 P20936,Q12756,O75489,P46100,P00846,P51608 6 +Adrenocortical carcinoma 0.4865707747791379 0.216004629631803 0.8289841388291928 1.0 1.0 4 P42771 1 +Abnormal finger phalanx morphology 0.2579225181052893 0.2158855800451744 0.8290769375266169 1.0 1.0 139 O95202,Q03164,O94761,P18077,Q71SY5,P62899,O75844,Q12756,Q5JRA6,P21281,O43318,Q01968,P62244,Q15067,P39019,P61353,P42766,Q9Y2Q9,Q15427,P51608,P15924 21 +Abnormality of the cervical spine 0.2556576942747863 0.2157299280417388 0.8291982712654822 1.0 1.0 89 Q53EZ4,P18077,Q9C0B1,P36507,P62899,P62081,Q9UQ13,Q8TC12,Q96HY6,P18074,Q5SRE5,P21281,P62244,P39019,Q07864,Q06265,P61353,P42766,P37837,Q9Y2Q9,Q15427,Q9NXE4,P46100,P51608 24 +Bowing of the legs 0.2742370734449535 0.2140417638070743 0.8305144889823401 1.0 1.0 43 Q01968,O94761,P36507,P46100,Q96HY6 5 +Gingival recession 0.4996980610305039 0.2116530929791563 0.8323776853289921 1.0 1.0 3 P15924 1 +Inappropriate antidiuretic hormone secretion 0.4119133574007166 0.2111029658713057 0.8328069259528057 1.0 1.0 2 P50336 1 +Abnormality of the musculature of the limbs 0.2538161187402332 0.2091907948668042 0.834299298092696 1.0 1.0 145 P07196,P18077,Q08209,P00846,P35609,P62899,Q12756,P04792,Q9BQT8,P20936,O43318,P62244,Q15067,P31749,P39019,O75190,Q8NC96,P42695,P61353,P42766,Q96RL7,P46100 22 +Pulmonic stenosis 0.2922981410626658 0.2091681339545253 0.8343169876085137 1.0 1.0 25 O75306,O43318,P61353,Q9UQ13,P36507 5 +Caesarian section 0.4826920848285452 0.2081415997703165 0.8351184064560948 1.0 1.0 4 Q96EY7 1 +Abnormality of male internal genitalia 0.3442074112089038 0.2079096237080545 0.8352995347351095 1.0 1.0 10 Q8IWS0,P13051 2 +Cleft lip 0.2741587705977935 0.2076130024480359 0.8355311510919206 1.0 1.0 47 O95202,P62244,P61353,Q9H9Y6,P42766,P14923,P18077,Q15427,P62899 9 +Coarctation of aorta 0.2834563334606051 0.2072073507378007 0.8358479268339036 1.0 1.0 33 P62244,P61353,P42766,P18077,P62899 5 +Peripheral axonal degeneration 0.2673403452209204 0.205572103368943 0.8371251703717764 1.0 1.0 64 Q13057,Q15067,Q12756,P07196,Q9NVI7,P04792,Q96RL7,P40763,P00846,Q9BQT8 10 +Aplasia hypoplasia affecting bones of the axial skeleton 0.2539859286442278 0.2055262468807723 0.8371609937288502 1.0 1.0 191 O95202,Q13057,Q03164,Q9H9Y6,O94761,Q9NVI7,P18077,Q08209,Q9NX62,P62899,O75844,Q15392,Q96ST3,O60762,Q96HY6,Q9NX14,P21281,O43318,Q01968,P62244,P31749,Q07864,P61353,P42766,Q15427,P46100,P51608 27 +Thin vermilion border 0.2625993228063181 0.2029459451745801 0.8391772823849182 1.0 1.0 115 Q03164,Q13868,O75844,Q92643,Q14004,Q96ST3,Q9UQ13,Q96HY6,Q96KP1,P21281,Q01968,Q8IZT6,Q00839,P42695,P32322,P37837,Q9Y3E5,Q9BSJ2,Q9NXE4,P46100,P51608,O15294,Q86XL3,P18583,P29372 25 +Multiple lentigines 0.3821690905923411 0.2020515335012825 0.839876436990963 1.0 1.0 6 Q9UQ13,P10644,P36507 3 +Abnormality of neuronal migration 0.2620990643942389 0.2013176194248093 0.8404502262884437 1.0 1.0 122 P42695,Q15392,P21281,P07954,Q8IZT6,P31749,Q12756,Q9Y3C6,P51608,O94761,Q96F86,O95721,Q08209,Q15427,Q71SY5,P23786 16 +Non midline cleft lip 0.3872874037728767 0.1962314314592119 0.8444290275359827 1.0 1.0 5 Q15427 1 +Ophthalmoparesis 0.2649640236480635 0.1956694984393838 0.8448688596096623 1.0 1.0 66 P22570,P31749,O75489,P00846,P35609,Q9UNE7 6 +Confusion 0.310866797131697 0.1948495107826615 0.845510761049052 1.0 1.0 13 P36551,Q9Y619,Q9NZ08,Q16836,P18074 5 +Abnormal circulating fatty acid anion concentration 0.3206975774053453 0.1944965309350466 0.8457871117780504 1.0 1.0 12 P55084,P23786,Q4G0N4 3 +Decreased fertility in females 0.3788864786695441 0.1944547581312888 0.8458198172943909 1.0 1.0 6 P57076,P51809,Q86Y56,Q8IY37,O00170 5 +Abnormality of the posterior pituitary 0.367695970595721 0.1942957917624406 0.8459442805374395 1.0 1.0 7 P31749 1 +Cone shaped epiphysis 0.3480526603461576 0.1942665834972501 0.8459671496632057 1.0 1.0 9 Q5JRA6,O43318,P10644,Q9Y2Q9 4 +Lymphoma 0.2889345440511231 0.1926282493345389 0.8472501194794109 1.0 1.0 24 O94761 1 +Macroglossia 0.2846031545928249 0.1918619085284039 0.8478503756565683 1.0 1.0 30 P21281,P31749,Q10713,Q96A33,Q9C0B1,P46100,P10253 7 +Female infertility 0.4884671113105449 0.1900124023925088 0.8492994118789763 1.0 1.0 3 P57076 1 +Hypotelorism 0.2831076431508146 0.1900055275571811 0.8493047990728644 1.0 1.0 31 A5YKK6,P32322,O94761,Q8TD30,Q9NXE4,P18074 6 +Leukodystrophy 0.2712376551453714 0.1896842101004179 0.8495565946867472 1.0 1.0 52 P04350,O75306,O15160,Q4G0N4,Q15067,Q8TB37,O43681,O75489,O43676,Q86Y39,Q16795,Q9NX14 12 +Abnormal reticulocyte morphology 0.2839741239100263 0.1889154532766926 0.8501590816973377 1.0 1.0 30 P62244,P61353,P42766,P39019,P18077,P62899 6 +Photophobia 0.2795362783911655 0.1873056004376011 0.8514210321830367 1.0 1.0 33 Q10567,Q13432,Q9NZ08 3 +Steppage gait 0.2936176850773426 0.1864345628303406 0.8521039903140968 1.0 1.0 18 P04792,P07196 2 +Acanthosis nigricans 0.3361736284321398 0.1857885011234006 0.8526106223132961 1.0 1.0 10 P31751 1 +Abnormality of chorioretinal pigmentation 0.3823348658700581 0.1854819920591979 0.8528510034538674 1.0 1.0 5 Q5XKP0 1 +Abnormal blood potassium concentration 0.3440950264974173 0.1840807171653598 0.8539501334502895 1.0 1.0 9 Q13423,Q9H3U1,Q01968 3 +Poor suck 0.2862930895877982 0.1827189611385818 0.8550185373851771 1.0 1.0 21 P21281,P55084,O75306,P37837,Q16851 5 +Episodic tachypnea 0.3619488414667869 0.1808416935948111 0.8564918358593487 1.0 1.0 7 P51608 1 +Tracheal stenosis 0.4670169218344201 0.1781175273284962 0.858630677315493 1.0 1.0 4 Q96HY6 1 +Abnormal right ventricle morphology 0.3788399541096883 0.1781076630359047 0.8586384240238658 1.0 1.0 5 Q7Z392 1 +Abnormality of fontanelles 0.2685301623677456 0.1778981315667332 0.8588029782353128 1.0 1.0 44 O94761 1 +Birth length less than 3rd percentile 0.479164339356619 0.1731824945023095 0.862507983093391 1.0 1.0 3 Q9NXE4 1 +Scaphocephaly 0.4790411856194548 0.1729664033181838 0.8626778358170872 1.0 1.0 3 P48444 1 +Acne inversa 0.4775022601423557 0.1702809634820183 0.8647891815626059 1.0 1.0 3 Q92542 1 +Immunologic hypersensitivity 0.2803214845710021 0.1688816099496846 0.8658897645512276 1.0 1.0 29 Q9NZ08,P40763,P18074,Q5JRA6,Q13043 5 +Hypoplasia of the pons 0.2917315469005184 0.1685208389613717 0.866173550986314 1.0 1.0 15 Q9Y3C6,Q9UNE7 2 +Chorea 0.2575980766203983 0.1684280808339206 0.8662465183413866 1.0 1.0 76 P04350,P22033,Q08209,P00846,Q71SY5,Q12756,O43681,Q5XKP0,P18074,Q4G0N4,Q14671,Q6IA86,Q7Z392,Q9H1B7,O75306,Q96F86,Q96RL7,P51608,Q9UNE7 19 +Limited extraocular movements 0.373713314543564 0.1676096086893425 0.8668904115054845 1.0 1.0 5 O75306 1 +Hemiplegia hemiparesis 0.2752639210929836 0.166413866629545 0.8678312621164523 1.0 1.0 33 P31749 1 +Abnormality of exocrine pancreas physiology 0.2900197653853785 0.1630674304903749 0.8704653432184264 1.0 1.0 15 P42771,Q8WX93,P09601,P40763,Q9Y3E5 5 +Hypometric saccades 0.473094980137239 0.1627423385883204 0.8707213099702289 1.0 1.0 3 P04062,P49959 2 +Central sleep apnea 0.3708997200878369 0.1620104794819677 0.8712976014617138 1.0 1.0 5 Q96A33 1 +Abnormal hair laboratory examination 0.3639049827257503 0.1618418979909247 0.8714303581259353 1.0 1.0 6 Q9Y276 1 +Choriocarcinoma 0.4550153448502008 0.1570590667411857 0.8751982971465615 1.0 1.0 4 P42771 1 +Migraine 0.2808603446585315 0.153367335951494 0.8781086022464515 1.0 1.0 20 Q9NZ08 1 +Horizontal eyebrow 0.3855595667869971 0.1530201524513426 0.8783823830885189 1.0 1.0 2 Q96T58 1 +Abnormality of the nasal tip 0.2491743006860445 0.152730177415518 0.8786110618137282 1.0 1.0 90 Q96KP1,O75844,P21281,O43318,Q03164,Q96A33,P46100,Q71SY5 8 +Keratitis 0.3230781711605358 0.1524637034587233 0.8788212161608588 1.0 1.0 10 Q15149,P18074,Q9NZ08 3 +Productive cough 0.3479085908133724 0.1502324463914967 0.8805812278642862 1.0 1.0 7 P57076,P40763 2 +Hypoglycemic seizures 0.3475536439357123 0.1495006990235426 0.8811585578253849 1.0 1.0 7 Q16836,Q13423,P31751 3 +Impaired pain sensation 0.2827181734687077 0.1485073502444506 0.8819423856208692 1.0 1.0 18 P04792,P51608,P07196 3 +Optic nerve hypoplasia 0.284418364989969 0.1480975495200727 0.8822657833210148 1.0 1.0 16 P07196,Q9NVI7 2 +Bone marrow hypercellularity 0.3359806215740739 0.147000393406087 0.8831317098010059 1.0 1.0 8 P40763,P62263,P10644 3 +Barrel shaped chest 0.4633441675695231 0.1468665175970875 0.8832373803787787 1.0 1.0 3 Q14739,Q96AX1 2 +Renal salt wasting 0.3815884476534232 0.1453551383833572 0.8844304827957647 1.0 1.0 2 Q13423 1 +Urinary retention 0.4478464933773231 0.1452867711882194 0.8844844589663412 1.0 1.0 4 P20936 1 +Coronal cleft vertebrae 0.4618295799012338 0.1444998191300334 0.8851057992657394 1.0 1.0 3 O75369 1 +Capillary malformation 0.2839359038115718 0.1443548045427991 0.8852203036784572 1.0 1.0 15 Q71SY5 1 +Atresia of the external auditory canal 0.2933710047749971 0.1428839424031114 0.8863818405474695 1.0 1.0 13 Q15427 1 +Gingival bleeding 0.3104068757710999 0.1416661180978045 0.8873437388053587 1.0 1.0 11 Q96JJ3,P40763 2 +Abnormal phalangeal joint morphology of the hand 0.2722619010683426 0.1406713933004705 0.8881295451737743 1.0 1.0 31 O75844,Q71SY5,O43318 3 +Hyperpigmentation of the skin 0.2553913600606393 0.1403854239178932 0.888355473832112 1.0 1.0 73 O75844,P21281,P31749,Q06136,P51648,Q96ST3,O94761,Q9NX14 8 +Impaired temperature sensation 0.3588779212376489 0.1393938360578314 0.8891389429224024 1.0 1.0 5 P04792 1 +Recurrent paroxysmal headache 0.330383900499997 0.1353319777112639 0.8923494030811665 1.0 1.0 8 P07954,P10644,P40926,P00403 4 +Adrenocorticotropic hormone deficiency 0.3758122743682252 0.1347137478754213 0.8928382030460225 1.0 1.0 2 O00170 1 +Abnormal circulating dehydroepiandrosterone concentration 0.3758122743682247 0.1347137478754205 0.8928382030460231 1.0 1.0 2 Q13423 1 +Esophageal atresia 0.4406415252542323 0.1340642071214766 0.89335180266589 1.0 1.0 4 Q9Y2W2 1 +Distal peripheral sensory neuropathy 0.4401572217375544 0.1333317293520285 0.8939310352193086 1.0 1.0 4 P55084,Q5T440 2 +Decreased circulating igg level 0.3055887956156927 0.1301276870083703 0.896465405291714 1.0 1.0 11 P13051,P18074 2 +Colon cancer 0.2880454852974233 0.1286115186778455 0.8976650514235023 1.0 1.0 13 P39019,P42771,Q8WX93 3 +Encephalocele 0.31236821252699 0.1277943173093036 0.8983117473202409 1.0 1.0 10 Q10713,Q9H9Y6 2 +Cns demyelination 0.2876169028140865 0.1274948477232595 0.898548750826947 1.0 1.0 13 P51648 1 +Abnormal macroscopic urine appearance 0.2745702007023484 0.1262275858641364 0.8995517756463456 1.0 1.0 19 P23786,P36551,Q9NQW6,P52565 4 +Elevated circulating glutaric acid concentration 0.4353323699422033 0.1261846480431912 0.899585763312545 1.0 1.0 4 Q92947,P38117,P13804 3 +Functional abnormality of the inner ear 0.2525836746089286 0.1255295112656971 0.9001043632030363 1.0 1.0 214 O95202,Q9Y276,P07196,P33527,P00846,P35609,O75844,Q86Y39,Q13217,Q9NX14,Q5JRA6,Q8N2K0,P21281,Q96JJ3,O43318,Q15067,O75489,Q9NZ08,Q10567,Q9NWH9,P40763,O95721,O95140,P07954,Q8TB37,P14923,O43676,Q96F86,Q9NSV4,P46100,O95470,O00303,P51608,Q9Y3E5,P15924 35 +Brachycephaly 0.2596376100697667 0.1247778180179331 0.9006994487846316 1.0 1.0 56 P21281,Q9H9Y6,O94761,Q96A33,P51608,Q9Y3E5 6 +Diffuse mesangial sclerosis 0.2752588511952456 0.124681072646634 0.900776042300092 1.0 1.0 18 Q9NQW6,P52565,O95470 3 +Mediastinal lymphadenopathy 0.4476483876520593 0.1236313729614539 0.9016071510116364 1.0 1.0 3 P01889 1 +Hyporeflexia of lower limbs 0.3243008419518477 0.1232859755580787 0.9018806459919796 1.0 1.0 8 P04792,P55084,Q5T440 3 +Abnormal preputium morphology 0.432442196531804 0.1220338868162224 0.9028721810271738 1.0 1.0 4 O60828,O60832,Q9NVI1 3 +Severe global developmental delay 0.2594065472473499 0.1219444361672602 0.9029430232389256 1.0 1.0 55 Q96KP1,P51970,P57678,Q15067,P51608,Q16851,O60762,Q96A33,P00846,Q71SY5 10 +Fluctuations in consciousness 0.3483917600289116 0.1214050720268373 0.9033701997020842 1.0 1.0 5 O75306,Q9UJS0,P04062,P00403 4 +Missing ribs 0.332936963515687 0.1211891149695009 0.9035412455662928 1.0 1.0 7 P21281 1 +Congestive heart failure 0.2581253584035405 0.1200244950077065 0.9044637440116716 1.0 1.0 58 P20936,P14923,P39019,P51608,Q70HW3,P35609,O95721,Q9NX14,Q13043,P15924 10 +Fused cervical vertebrae 0.3317301845493534 0.1190110034736027 0.9052666382296192 1.0 1.0 7 O43318 1 +Aplasia hypoplasia of the tibia 0.3660649819494525 0.1181101392545612 0.9059803897245484 1.0 1.0 2 O75369 1 +Short tibia 0.3660649819494525 0.1181101392545612 0.9059803897245484 1.0 1.0 2 O75369 1 +Spastic paraplegia 0.257141551460703 0.1178493500141293 0.9061870263065216 1.0 1.0 43 Q12756,O75489,P46100,P00846,P51608 5 +Positional foot deformity 0.2494131072085108 0.117189667236787 0.9067097548495362 1.0 1.0 78 O95202,Q15392,O43318,P10412,Q8NBU5,Q12756,O94761,P07196,Q9NVI7,P04792,Q08209,Q15427,Q96A33,P46100,Q9Y3E5 15 +Abnormal metacarpal morphology 0.2682210684696996 0.116603484195481 0.9071742765738982 1.0 1.0 27 O94761,O43318 2 +Aplasia hypoplasia involving the sinuses 0.4283620092772011 0.1163398528194165 0.9073832020561916 1.0 1.0 4 P46100 1 +Abnormal cerebrospinal fluid metabolite concentration 0.3205499276410938 0.1161892160532426 0.9075025832093566 1.0 1.0 8 O00483,P51649,P10515,Q9UDR5,P36776,Q15046,Q8TCS8 7 +Follicular hyperkeratosis 0.3451391398626636 0.116154619059184 0.9075300019704756 1.0 1.0 5 Q9NWM8,Q02809,Q6P1M0,Q9H488 4 +Bifid scrotum 0.4281069364161918 0.1159903180428106 0.907660215084698 1.0 1.0 4 Q69YQ0,Q96EK5,P16435 3 +Epiphyseal dysplasia 0.4409534127844009 0.114584671838812 0.9087743297770065 1.0 1.0 3 Q14807,O75369 2 +Abnormal aortic valve physiology 0.2659307990341209 0.1143238076040186 0.9089811104864044 1.0 1.0 31 O75844 1 +Abnormality of the hairline 0.2489591832893131 0.1139285386281583 0.9092944422992422 1.0 1.0 78 O95202,Q9H9Y6,P18077,P36507,P62899,Q92643,O15160,P36551,Q96ST3,Q9UQ13,Q16851,P21281,O43318,P62244,P39019,Q9Y2W2,P61353,P42766,Q9NXE4,P29372 20 +Focal segmental glomerulosclerosis 0.2671756817297702 0.1128189815645327 0.9101740693088194 1.0 1.0 21 Q9NQW6,P52565,O95470 3 +Hypertrichosis 0.2421708418086345 0.1110933848692322 0.9115422943813204 1.0 1.0 87 Q9Y5P4,Q03164 2 +Abnormal renal cortex morphology 0.2577610001291637 0.1105731895658629 0.911954808714348 1.0 1.0 51 P07954,Q01968,Q9NZ08,Q9NQW6,O95470,P00846 6 +Joint dislocation 0.2478005917746999 0.1105615761187381 0.9119640184369988 1.0 1.0 79 O95202,O75844,O43318,Q01968,P31749,O94761,Q15427,Q96A33,Q9Y3E5 9 +Decreased patellar reflex 0.437225827606559 0.1097691406365607 0.9125924653198818 1.0 1.0 3 P55084 1 +Sparse hair 0.2515675617823798 0.1095416622619181 0.9127728788614702 1.0 1.0 71 O75844,Q13868,O60828,Q01968,P32322,P49589,P14923,O94761,Q9UQ13,Q8IWS0,Q15427,Q9H7N4,P36507,Q71SY5,P18074,P15924 16 +Pes cavus 0.2443398681982851 0.1094471127307509 0.91284786760178 1.0 1.0 83 P21281,Q13057,O00764,O43318,P07196,P04792,Q96RL7,Q71SY5,Q8N2K0 9 +Inverted nipples 0.4228734676427689 0.1089849496993594 0.9132144276236828 1.0 1.0 4 O60762 1 +Abnormality of the peripheral nervous system 0.2442254156336716 0.10858378389514 0.913532623272105 1.0 1.0 83 O95140,Q15067,Q12756,P51608,Q9H0U9,P07196,O95721,Q9NSV4,P04792,Q96RL7,Q15427,P46100,Q71SY5,Q9Y3E5,Q8N2K0 15 +Infertility 0.2955708319298605 0.1077852375035308 0.9141660534272408 1.0 1.0 11 P57076,Q9UNE7 2 +Abnormality of the pancreas 0.2517861805208654 0.1069951901046847 0.9147927955915358 1.0 1.0 66 O75489,O94761,Q9NZ08,P09601,Q13043,Q9UNE7 6 +Abnormality of the clitoris 0.2680368900175049 0.1059737112323537 0.9156032101086689 1.0 1.0 19 P22570 1 +Abnormality of earlobe 0.2656747030149999 0.1058767336668406 0.915680154135941 1.0 1.0 22 Q15392,Q8IWS0,O60701,Q8TC12,Q9NX14 5 +Delirium 0.3581227436823043 0.1058194020501587 0.9157256426104596 1.0 1.0 2 P26358 1 +Urinary tract neoplasm 0.2634684902449767 0.1045789819650211 0.9167098931997252 1.0 1.0 31 P31749 1 +Abnormality of the neck 0.2444530562391352 0.1042851776142206 0.9169430403234282 1.0 1.0 145 O95202,P04350,Q03164,Q9H9Y6,Q53EZ4,Q14738,P18077,Q9C0B1,P36507,P62899,O75844,O15160,P62081,Q9UQ13,Q8TC12,Q96HY6,P18074,Q5SRE5,P21281,O43318,P62244,P31749,P39019,Q9Y2W2,Q07864,Q06265,P61353,P42766,P37837,Q9Y2Q9,Q9NXE4,P46100,P51608 33 +Abnormal thoracic spine morphology 0.2651761057865252 0.1023885234550182 0.9184482927534608 1.0 1.0 24 O75844 1 +Abnormal choroid morphology 0.2648670773996316 0.1013560460113888 0.919267826929167 1.0 1.0 24 Q9NX14,P31749 2 +Abnormal chorioretinal morphology 0.2648670773996316 0.1013560460113888 0.919267826929167 1.0 1.0 24 Q9NX14,P31749 2 +Distal arthrogryposis 0.4167773199199576 0.1012219602766306 0.9193742644679208 1.0 1.0 4 Q96A33 1 +Contractures of the joints of the upper limbs 0.2540708809807536 0.0991016063445644 0.921057596689759 1.0 1.0 59 O75844,Q15392,O43318,Q01968,P51608,P07196,Q71SY5 7 +Recurrent ear infections 0.4279523293607819 0.0984676378897551 0.9215609682709458 1.0 1.0 3 P39656,P61011 2 +Abnormal larynx morphology 0.2632744643727224 0.0962085950251144 0.9233549046406816 1.0 1.0 25 Q96HY6,Q15427 2 +Abnormal vena cava morphology 0.3091155609294753 0.0961099400998803 0.9234332567979492 1.0 1.0 8 Q71SY5,P57076 2 +Gastroesophageal reflux 0.2496182190349795 0.0946617585311855 0.924583493799548 1.0 1.0 107 O95202,P21281,O43318,Q03164,Q01968,Q08209,P00846,Q96A33,P46100,Q8NC96,P51608,Q9Y584,P15924 13 +Noncompaction cardiomyopathy 0.4239797760924471 0.0939186166268843 0.925173805273521 1.0 1.0 3 Q15233,P31040 2 +Recurrent bacterial infections 0.264432444547882 0.0932653085192032 0.9256927917127218 1.0 1.0 18 P13051,Q13043,P40763 3 +Prominent nasal bridge 0.2514533942760037 0.0923930735271554 0.9263857424153444 1.0 1.0 42 Q96ST3,O94761,Q15427,P51608,Q5JRA6 5 +Pancreatic adenocarcinoma 0.3067538675086966 0.0922528250526042 0.9264971686222988 1.0 1.0 8 Q8WX93 1 +Polyuria 0.3270393748562072 0.08975869405912 0.9284789730077424 1.0 1.0 5 P18583 1 +Abnormality of acid base homeostasis 0.2390984247648693 0.0892781590437078 0.9288608513041628 1.0 1.0 151 P55084,Q9Y276,Q10713,P14927,Q5JTZ9,Q9NVI7,P22033,Q9HCC0,Q6P4A7,P00846,Q9Y606,P51970,Q86Y39,Q5XKP0,Q9NX14,Q9Y584,Q5JPH6,Q9UBX3,O14949,P13073,Q4G0N4,Q01968,O75489,Q70HW3,Q16795,Q16836,P23786,O75306,P07954,Q8TB37,Q99797,Q9Y2Z4,Q9Y619,O43676,Q9H0R6,Q9Y2Q9,O75251,P51608,P35610 39 +Broad eyebrow 0.2921207348377043 0.0876103262971145 0.930186394543558 1.0 1.0 10 Q96ST3 1 +Palmar pits 0.3444043321299576 0.0871295049149862 0.9305685730297916 1.0 1.0 2 Q9H488 1 +Aplasia hypoplasia of the vagina 0.4174792343806436 0.0868460985525911 0.9307938446741926 1.0 1.0 3 P51809,P30153 2 +Autosomal dominant germline de novo mutation 0.3440433212996328 0.0866798992024686 0.9309259543836216 1.0 1.0 2 P24928 1 +Abnormal csf carboxylic acid concentration 0.3203181489515395 0.0866614560731329 0.9309406147054872 1.0 1.0 6 O00483,P51649,P10515,Q9UDR5,P36776 5 +Abnormal paranasal sinus morphology 0.2621658256787027 0.0864521878129997 0.9311069623053408 1.0 1.0 17 Q13432,P46100 2 +Abnormal foramen magnum morphology 0.4167821596342759 0.0861147358741701 0.9313752096067448 1.0 1.0 3 P54886 1 +Hyperkinetic movements 0.2836912259336795 0.0841816641911221 0.932911996291506 1.0 1.0 11 Q96RL7,Q96TA2 2 +Abnormal circulating igg level 0.2689100623857829 0.0834251214755836 0.9335135140842954 1.0 1.0 13 P13051,P18074 2 +Abnormal serum interleukin level 0.3404332129963835 0.0822997804818822 0.9344083289798576 1.0 1.0 2 P09884 1 +Hand muscle weakness 0.3001367939259246 0.0819691531453843 0.9346712431098704 1.0 1.0 8 P07196 1 +Myoglobinuria 0.2885584112514188 0.0814107782973571 0.935115277722916 1.0 1.0 10 Q16836,P55084,P23786 3 +Brain imaging abnormality 0.2579911119012842 0.0811002696874148 0.9353622112164804 1.0 1.0 27 P31749 1 +Abnormality of the basal ganglia 0.2467959250628409 0.0807442382525606 0.9356453546109682 1.0 1.0 72 Q13057,P22570,O75489,Q96F86,P00846,Q71SY5 6 +Lower limb hypertonia 0.2873205469149 0.0793167881089967 0.9367806533899864 1.0 1.0 10 Q14739,P54136,O60341,P54886,P46100 5 +Neoplasm of the gallbladder 0.397270614892711 0.0791885670890694 0.9368826381760844 1.0 1.0 4 Q13043 1 +Biliary tract neoplasm 0.397270614892711 0.0791885670890694 0.9368826381760844 1.0 1.0 4 Q13043 1 +Pierre robin sequence 0.2979825665383325 0.0787863052005661 0.9372025970516148 1.0 1.0 8 O43318,Q8WYQ5 2 +Pace of progression 0.2401266651099744 0.078653011115362 0.9373086213299164 1.0 1.0 148 Q13057,Q8NBU5,Q86U42,P07196,P52565,Q5JTV8,O14773,Q12756,P04792,O60762,Q5XKP0,Q8N2K0,O00764,P31749,Q14671,Q8TD30,Q6IA86,O75190,Q99986,O95140,Q06265,Q96RL7,O95470,P51608,Q9Y3E5,Q9UNE7 26 +Abnormality of the 5th toe 0.3173179224632028 0.0775182278502336 0.9382112911762546 1.0 1.0 5 Q10713 1 +Postaxial foot polydactyly 0.3173179224632028 0.0775182278502336 0.9382112911762546 1.0 1.0 5 Q10713 1 +Muscle hypertrophy of the lower extremities 0.2962875726233356 0.0763384485685558 0.9391498375389292 1.0 1.0 8 P20936,Q15149 2 +Muscle fiber atrophy 0.2565959739396736 0.0761887719928686 0.9392689153770872 1.0 1.0 20 P35609,Q96RL7,P23786 3 +Abnormality of the 1st metacarpal 0.2948625180897203 0.0743187195617564 0.9407567821645412 1.0 1.0 8 O60828,Q9UQE7,Q9BXW9,Q15233,Q08AM6,Q14683,Q9NVI1 7 +Exodeviation 0.2568574656476529 0.0742611689530072 0.9408025743687184 1.0 1.0 16 Q7Z392,Q9Y3E5,P46100 3 +Stuttering 0.3321299638989105 0.0730081987006565 0.9417995933043974 1.0 1.0 2 P00403 1 +Functional motor deficit 0.247405185964374 0.0728246378467392 0.9419456648420208 1.0 1.0 130 Q13057,Q9Y276,P07196,Q08209,P00846,Q71SY5,O14773,Q9H2D1,P04792,Q9NX14,P20936,Q15067,P31749,Q8TD30,O75190,Q8NC96,P23786,O95140,Q96RL7,P51608,Q9UNE7 21 +Elevated calcitonin 0.3007787353924734 0.0713641600560263 0.9431079329875244 1.0 1.0 7 P07954,P10644,P40926 3 +Hypertension associated with pheochromocytoma 0.3007787353924734 0.0713641600560263 0.9431079329875244 1.0 1.0 7 P07954,P10644,P40926 3 +Recurrent bronchopulmonary infections 0.3886393653633936 0.0707589225898979 0.9435896248633484 1.0 1.0 4 P18074,Q9Y2Q5 2 +Phenotypic variability 0.2367723771178042 0.0701179241411593 0.944099800412968 1.0 1.0 87 P07954,Q9Y276,Q12756,P00374,Q70HW3,Q9NWH9,P07196,Q15427,P00846,Q6P4A7,O60762,O95470,O95140 13 +Abscess 0.3073944660476487 0.0699583820599465 0.9442267847431354 1.0 1.0 6 Q8WX93 1 +Delayed gross motor development 0.2360329693830995 0.0699419206284307 0.9442398869711912 1.0 1.0 86 P54577,Q03164,Q10713,Q14738,P35609,P50570,P10253,P22570,Q14004,P51970,Q9UQ13,Q7L2E3,P49589,O95140,Q92989,Q15149,O60701,P51608,P34897,P18583 20 +Biconcave vertebral bodies 0.3096665871060325 0.0688053956084746 0.9451445231943616 1.0 1.0 5 P32322 1 +Vertebral clefting 0.2962220206803108 0.0656531261855623 0.9476539917341492 1.0 1.0 7 Q9Y2W2,O75369 2 +Abnormal endocrine physiology 0.3064691001084184 0.065398573690876 0.9478566596803646 1.0 1.0 5 P16435,P50336,Q13423,Q13724 4 +Neoplasm of the gastrointestinal tract 0.2398018165892496 0.0651057865170333 0.94808977323557 1.0 1.0 81 P62244,P61353,P42766,P31749,P39019,Q9NWH9,P18077,P46100,Q9UER7,Q13043,P62899,Q07864 12 +Abnormality of upper lip vermillion 0.2467736819369934 0.0641741470914414 0.9488315625841752 1.0 1.0 111 Q96KP1,P42695,P21281,Q92643,Q03164,Q8IZT6,Q01968,Q14004,P51608,P46100,Q71SY5,Q9Y3E5 12 +Underdeveloped supraorbital ridges 0.2719906366778898 0.0639644493536574 0.9489985341207176 1.0 1.0 11 P98175,P36507 2 +Unusual fungal infection 0.2825179121107479 0.0637543852155369 0.949165799648533 1.0 1.0 9 Q13043,P40763 2 +Decreased activity of the pyruvate dehydrogenase complex 0.2512656660885781 0.0601684276157483 0.9520214912528622 1.0 1.0 18 O75306,P11177,O75489,Q16795,O75251 5 +Hypoplastic toenails 0.2493398962142049 0.0594667076664265 0.9525803819650148 1.0 1.0 21 Q9UQ13,P23786,P21281 3 +Tremor by anatomical site 0.2505180833585688 0.0570202860071016 0.9545290355328816 1.0 1.0 25 Q96RL7,Q9UNE7,P07196 3 +Spondylolysis 0.3144404332129895 0.0566339483238033 0.9548367910815696 1.0 1.0 2 O75369 1 +Broad face 0.3144404332129895 0.0566339483238033 0.9548367910815696 1.0 1.0 2 O75369 1 +Capitate hamate fusion 0.3144404332129895 0.0566339483238033 0.9548367910815696 1.0 1.0 2 O75369 1 +Abnormal sclera morphology 0.2502554572750246 0.0563970052017433 0.955025542662992 1.0 1.0 26 P31749 1 +Abnormal meningeal morphology 0.2481074452339139 0.0562116192076867 0.9551732250101188 1.0 1.0 21 P20936,Q96ST3,Q10713,P18583 4 +Abnormality of female external genitalia 0.2499380551614642 0.0561503562362094 0.955222028708756 1.0 1.0 31 Q15392,P22570 2 +Abnormality of the adrenal glands 0.2466015756355353 0.0549961942354348 0.9561414957661324 1.0 1.0 51 O75844,P21281,Q01968,P31749,O95470,Q07864 6 +Impaired mastication 0.29475182064075 0.0540542643163211 0.9568919307269232 1.0 1.0 5 Q14738 1 +Acetabular dysplasia 0.2787590750603043 0.0538709622759039 0.9570379718067048 1.0 1.0 8 Q9Y584,P62244 2 +Abnormal shape of the occiput 0.2467406199619513 0.0526667272853331 0.95799744999604 1.0 1.0 21 P21281,Q01968 2 +Lymphoproliferative disorder 0.377031419284938 0.0525402010887482 0.9580982637161748 1.0 1.0 3 P50851,P33991 2 +Anterior pituitary dysgenesis 0.3061371841155164 0.050421630774699 0.959786399442456 1.0 1.0 2 Q15233 1 +Microretrognathia 0.2445855197028664 0.0500950477116691 0.9600466461388208 1.0 1.0 14 Q15427 1 +Inflammation of the large intestine 0.2503233622145758 0.0486113560220082 0.9612290198688388 1.0 1.0 13 O43318 1 +Decreased circulating aldosterone level 0.3025270758122674 0.0479895779420136 0.9617245486356591 1.0 1.0 2 Q13423 1 +Abnormal toenail morphology 0.2407039148836041 0.0478470562306433 0.96183813402835 1.0 1.0 41 O75844,P21281,Q12756,P14923,P15924 5 +Skeletal muscle hypertrophy 0.239856555775448 0.0474275299748602 0.9621724879562898 1.0 1.0 40 P21281,P20936,Q96A33,P31749 4 +Abnormality of the calcaneus 0.2856109906001371 0.047210437061807 0.9623455092262954 1.0 1.0 6 Q14739,P55084,O43175,P21333,O75369 5 +Food allergy 0.3580202312138771 0.0468660593497209 0.9626199790709262 1.0 1.0 4 Q01082,Q6P1M0,O95394 3 +Symptomatic seizures 0.2719021298073698 0.0464426217353661 0.9629574659118598 1.0 1.0 8 Q16836,Q13423,P31751 3 +Chorioretinal degeneration 0.2855077701481736 0.0463140758511844 0.9630599204415108 1.0 1.0 5 O75695,Q9Y619,P04181,P35222 4 +Diffuse cerebellar atrophy 0.2843468510322506 0.0460871516148855 0.9632407866535292 1.0 1.0 6 Q12756 1 +Abdominal aortic aneurysm 0.3647526182737421 0.0451127294983205 0.964017455080914 1.0 1.0 3 P31153,P01889 2 +Severe short limb dwarfism 0.3647526182737424 0.0451127294983205 0.964017455080914 1.0 1.0 3 Q14739,O75369 2 +Serositis 0.2442416896651993 0.0443335289366449 0.964638545712662 1.0 1.0 19 Q9NZ08,Q9NQW6,P52565 3 +Addictive behavior 0.2828040076930642 0.0442420767374731 0.9647114424851302 1.0 1.0 5 P40763 1 +Metrorrhagia 0.2828040076930642 0.0442420767374731 0.9647114424851302 1.0 1.0 5 P40763 1 +Diffuse alveolar hemorrhage 0.2828040076930642 0.0442420767374731 0.9647114424851302 1.0 1.0 5 P40763 1 +Sparse lateral eyebrow 0.2747990729187464 0.0429909243613612 0.9657087684768856 1.0 1.0 7 Q92643 1 +Abnormal ovarian morphology 0.2446057285868188 0.0418212753305912 0.966641174587604 1.0 1.0 24 P31749 1 +Lissencephaly 0.2421421820231423 0.0418107858444353 0.9666495366725728 1.0 1.0 46 Q9UPN3,Q15392,P42695,Q9H2M9,Q8IZT6,P36543,Q9BSJ2,Q08AM6,Q9C0B1,O00139,O95721,P23786,Q86XL3 13 +Abnormal circulating serine concentration 0.3582520765619337 0.0416736886020703 0.966758829187586 1.0 1.0 3 Q9Y617,O43175 2 +Hypergalactosemia 0.3582520765619323 0.0416736886020694 0.9667588291875866 1.0 1.0 3 Q96C23,P51570 2 +Semilobar holoprosencephaly 0.348988439306365 0.0414530492588132 0.9669347219185408 1.0 1.0 4 A5YKK6,Q8N3U4,Q14683 3 +Duplicated collecting system 0.2783803326102607 0.0410604705577119 0.9672476879347732 1.0 1.0 6 P41252,Q9BXW9,Q7Z3K3,Q9UQ13,P28482 5 +Abnormality of the fontanelles or cranial sutures 0.2359245466606006 0.0406797935505316 0.9675511706698718 1.0 1.0 92 O75844,P21281,O43318,P31749,Q12756,P39019,O94761,Q08209,P46100,Q5SRE5,Q9NX62 11 +Abnormality of facial soft tissue 0.2413607514663169 0.0403854971592037 0.9677857924073066 1.0 1.0 103 O75844,P20936,P31749,Q12756,P51608,O94761,P07196,O75190,Q96TA2,P35609,Q9BQT8,Q9Y3E5 12 +Multiple rows of eyelashes 0.3555792189185842 0.0403531131436021 0.9678116100675248 1.0 1.0 3 Q9Y606 1 +Primary gonadal insufficiency 0.2627578718783927 0.0400195323351446 0.9680775542144276 1.0 1.0 9 Q96MF7,P51809,Q8IY37,Q14232,O76024,Q9NR50,Q9UI10,Q13144 8 +Ridged nail 0.3446531791907589 0.0390935838891395 0.9688157763752894 1.0 1.0 4 P26639,O60832,P18074 3 +Delayed ability to sit 0.2381011111129714 0.038978699008068 0.9689073714343162 1.0 1.0 14 Q10713,O60701,P51608,P18583,P10253 5 +Impaired visuospatial constructive cognition 0.3433949136747516 0.038436661579053 0.9693395308548372 1.0 1.0 4 Q10713 1 +Myopathy 0.2338778600431071 0.0364333304729895 0.9709368379391758 1.0 1.0 83 Q8TB37,P31749,Q86U42,O43676,P07196,Q86Y39,O75190,Q96RL7,P00846,P35609,P23786,P15924 12 +Anosmia 0.338214145522015 0.0358600839269372 0.9713939237933562 1.0 1.0 4 O95140 1 +Abnormal prostate morphology 0.2659808129853183 0.0355439026526758 0.971646039221006 1.0 1.0 7 Q8IWS0 1 +Gastrointestinal inflammation 0.239815382249072 0.0349519220057465 0.9721180781073252 1.0 1.0 19 Q13043,O43318,Q8NBU5 3 +Abnormal megakaryocyte morphology 0.2685498902005122 0.0346649151752248 0.9723469377373136 1.0 1.0 5 P62263 1 +Limb muscle weakness 0.2381342602934281 0.0345772681125519 0.972416828076865 1.0 1.0 75 P20936,Q86U42,Q12756,P31749,Q15067,P07196,P04792,Q96RL7,P00846,P35609,Q9BQT8,O95140 12 +Pulmonary hemorrhage 0.2691930939873734 0.0341740884764963 0.9727383288687046 1.0 1.0 6 P40763 1 +Abnormality of circulating fibrinogen 0.2691536562899034 0.0341466735248925 0.9727601900763344 1.0 1.0 6 P40763 1 +Decreased plasma carnitine 0.25024238482162 0.034030433170915 0.9728528825886992 1.0 1.0 11 P23786,Q4G0N4 2 +Rimmed vacuoles 0.2355470268176511 0.0336288484748027 0.9731731175174256 1.0 1.0 15 P35609,O75190 2 +Amaurosis fugax 0.2632911392404981 0.0334750177381626 0.9732957876207676 1.0 1.0 7 P04637,Q16658,P01889,P27797,P60866,P43246 6 +Progressive 0.2379820285989885 0.0318942454098231 0.974556387804428 1.0 1.0 98 Q5XKP0,Q06265,O00764,Q13057,Q8NBU5,Q86U42,P31749,Q12756,Q14671,Q8TD30,Q6IA86,Q96RL7,O60762,Q99986,O95470,P51608,Q9Y3E5,Q9UNE7 18 +Abnormal circulating fatty acid concentration 0.2364948244310294 0.0316209301020003 0.9747743519271296 1.0 1.0 17 P55084,P23786,Q4G0N4 3 +Neoplasm of the larynx 0.2631008312251537 0.0315654381785245 0.9748186059849672 1.0 1.0 5 O96017,P43246,P04637,P42771 4 +Perisylvian polymicrogyria 0.3258670520231276 0.0305057983389429 0.975663669128978 1.0 1.0 4 Q9BVA1,P34897,P42345 3 +Temporal pattern 0.325505780346824 0.0303648876721521 0.975776047513698 1.0 1.0 4 P04062,Q04637,Q14683 3 +Respiratory failure requiring assisted ventilation 0.3244875665698441 0.0299723433432289 0.9760891100725284 1.0 1.0 4 Q9H9Y6 1 +Primary microcephaly 0.2316297992091592 0.0289934960770893 0.9768697777938672 1.0 1.0 14 P51608 1 +Respiratory failure 0.2407325534662308 0.028823472057905 0.9770053806600488 1.0 1.0 57 O75306,P55084,P15924,P57076,Q8NBU5,P14923,Q70HW3,Q15165,P23786,Q5XKP0,Q9NX14,Q5SRE5,P18583,P10253 14 +Diaphragmatic weakness 0.3246659443842529 0.0285817016358247 0.9771982061017443 1.0 1.0 3 P60174,P10253 2 +Diaphragmatic paralysis 0.3246659443842529 0.0285817016358247 0.9771982061017443 1.0 1.0 3 P60174,P10253 2 +Eeg with focal sharp waves 0.319971108703499 0.0272872474916579 0.97823062810995 1.0 1.0 3 Q9Y617,P36776 2 +Malignant hyperthermia 0.3188876850848613 0.0270044901986584 0.9784561526781042 1.0 1.0 3 P50570,O95163 2 +Central apnea 0.25329437334733 0.0265677656283456 0.9788044834818028 1.0 1.0 7 O76024 1 +Aplasia hypoplasia of the scapulae 0.3146676300578049 0.0265215536655431 0.9788413423054434 1.0 1.0 4 Q15738,P16435,Q08AM6 3 +Bulbar palsy 0.2458363504706804 0.0261699519003003 0.9791217825805334 1.0 1.0 10 P55072,P06753,O43681,P31483,Q13148,O75190,P19367,P53007,P43243 9 +Tibial bowing 0.3145539906103282 0.0259307899668992 0.9793125414567204 1.0 1.0 3 Q32P28,O75369 2 +Radial bowing 0.3145539906103282 0.0259307899668992 0.9793125414567204 1.0 1.0 3 Q32P28,O75369 2 +Cholecystitis 0.2471924624296505 0.0254316642356994 0.9797106548628078 1.0 1.0 8 P51608 1 +Striae distensae 0.24602026049204 0.0246406317519988 0.9803416096772252 1.0 1.0 8 P04637,Q13620,O00170,P17612,Q15334,P10644,Q96T58 7 +Abnormal response to endocrine stimulation test 0.3062477428674596 0.0241141572829347 0.98076155072783 1.0 1.0 3 P16435,Q13423 2 +Vertebral compression fracture 0.2286081867501952 0.0231556015972748 0.9815261538944556 1.0 1.0 15 Q96HY6 1 +Hydroureter 0.2434876989869753 0.0229898677423534 0.9816583551849144 1.0 1.0 8 Q9BXW9,Q9UQE7,Q16531,P21333,O76024,P36776,Q9NVI1 7 +Abnormal number of incisors 0.2432237079869897 0.0225742671603825 0.9819898704272294 1.0 1.0 5 A5YKK6,Q8N3U4,P38919,Q14683 4 +Tube feeding 0.2391231762935495 0.0217535982318723 0.9826445086644884 1.0 1.0 57 Q12756,O94761,Q96F86,Q08209,O60762,Q71SY5 6 +Anarthria 0.2454808387563205 0.0206939161310148 0.9834898222062968 1.0 1.0 6 Q15813,P54886,Q99720,Q8WVX9,P22314 5 +Accessory oral frenulum 0.281690140845066 0.020298707192889 0.9838050870861144 1.0 1.0 3 P17612,O15111 2 +Chorioretinal atrophy 0.2854046242774612 0.0193238592819983 0.984582750526209 1.0 1.0 4 Q9Y619,P04181,P35222 3 +Abnormal circulating free fatty acid concentration 0.2854046242774594 0.019323859281998 0.9845827505262092 1.0 1.0 4 Q16836,P49748,O75431 3 +Carpal bone hypoplasia 0.2796242774566512 0.0183500301552488 0.985359615880628 1.0 1.0 4 P54886,Q9Y5S9,Q14807 3 +Abnormal natural killer cell morphology 0.2499097146984404 0.0177931382420504 0.9858038787843736 1.0 1.0 3 P33991,O95394 2 +Reduced natural killer cell count 0.2499097146984404 0.0177931382420504 0.9858038787843736 1.0 1.0 3 P33991,O95394 2 +Fair hair 0.2499097146984408 0.0177931382420504 0.9858038787843736 1.0 1.0 3 P10644,Q13724 2 +Occipital meningocele 0.2256168810741931 0.0171761617313964 0.9862960795669612 1.0 1.0 5 Q10713 1 +Branchial anomaly 0.2328274677842197 0.0168716241332384 0.9865390302061074 1.0 1.0 8 Q9H9Y6 1 +High palate 0.2378984862802374 0.0168353117166749 0.9865679992081864 1.0 1.0 189 Q03164,Q9H9Y6,O94761,P07196,P18077,P36507,P35609,Q71SY5,P62899,O75844,Q96ST3,O60762,Q5SRE5,P21281,O43318,P62244,P31749,P39019,Q96A33,P40763,P23786,Q06265,P61353,P42766,P46100,P51608 26 +Erythroid hyperplasia 0.2684248554913327 0.0167946183766664 0.9866004632060952 1.0 1.0 4 Q9Y606,Q86SX6,P06132 3 +Abnormal hair pattern 0.235196491581551 0.0164373365916254 0.9868854934748994 1.0 1.0 97 O95202,Q9H9Y6,P18077,P36507,P62899,O75844,Q92643,O15160,P36551,O60828,Q96ST3,Q9UQ13,Q16851,P21281,O43318,P62244,P39019,Q9Y2W2,P61353,P42766,Q9NXE4,O15294,P29372 23 +Chronic oral candidiasis 0.2500000000000057 0.0150127277337911 0.988022026263962 1.0 1.0 4 Q03426,O75083,P02786 3 +Abnormal social behavior 0.2376015949006949 0.0148776266592604 0.988129809287606 1.0 1.0 54 Q15067,Q8TB37,Q9Y3C6,O75489,P51608,O43676,Q86Y39,Q9NX14,Q5XKP0,Q16851,P18074 11 +Thromboembolism 0.2453595320902431 0.0146862876380613 0.9882824590598908 1.0 1.0 4 O95235,P10644 2 +Abnormal circulating nitrogen compound concentration 0.2361542170764884 0.0146482407234916 0.988312812840451 1.0 1.0 48 Q01968,P61457,Q9HCC0,P51608,P23786 5 +Abnormality of prenatal development or birth 0.2416629179124627 0.0141914872122916 0.9886772115248328 1.0 1.0 205 O95202,Q9NVI7,P18077,Q9Y5P4,Q08209,P36507,P62899,O75844,P22570,Q96ST3,Q86Y39,Q9NX14,Q5SRE5,P21281,P20936,P62244,O75489,P39019,Q70HW3,Q8NC96,P23786,Q06265,P61353,P42766,P14923,O43676,Q15427,Q9Y3E5,P15924 29 +Cerebral visual impairment 0.2368967426976858 0.0119715631353044 0.9904483027617486 1.0 1.0 56 Q12756,Q96F86,Q9Y5P4,Q08209,Q96A33,Q71SY5 6 +Peptic ulcer 0.2204125950054284 0.0092315546693771 0.9926343896754296 1.0 1.0 9 Q9Y4P3,P04062,P78347,Q8N5K1,Q15056,P35250,O76024,Q6P1J9 8 +Dysuria 0.1974683544303725 0.0058063857031016 0.9953672005252324 1.0 1.0 7 P07741,P01889,Q8N5K1,O76024,O00170,P00492 6 +Pheochromocytoma 0.2004341534008648 0.005112353751197 0.9959209496410176 1.0 1.0 8 P07954,P40926,P31040,P36957,P10644,Q02978,P21912 7 +Abnormal renal collecting system morphology 0.1909584086799254 0.0047813759374045 0.9961850284961868 1.0 1.0 7 P41252,Q9BXW9,Q7Z3K3,Q9UQ13,Q9Y4R8,P28482 6 +Hiatus hernia 0.1983414295738901 0.0046345927746855 0.996302143217463 1.0 1.0 8 Q8NBU5 1 +Abnormal myelination 0.2338731925592051 0.0042505094845898 0.9966085943186948 1.0 1.0 180 P04350,Q13868,P07196,P22033,Q08209,P00846,P10253,O15160,P22570,P57678,Q12756,Q9Y3C6,Q86Y39,Q13217,O60762,Q9NX14,Q9Y584,Q5SRE5,P18074,Q96KP1,Q15067,O75489,P49589,Q8TD30,Q7Z392,Q8NC96,Q00839,O95140,O75306,Q8TB37,P51648,P00374,O43676,Q96RL7,Q9NXE4,Q9Y3C8 36 +Abnormal brain lactate level by mrs 0.1910274963820565 0.0031729781329937 0.997468333983967 1.0 1.0 8 O75306,Q99714,P00403,O43819,O00429,Q15046,P21912 7 +Abnormality of the gastric mucosa 0.2123957955781081 0.002889821444125 0.9976942592954888 1.0 1.0 13 Q14739,Q9Y4P3,P49327,P04062,P78347,Q8N5K1,Q15056,P35250,Q6PGP7,P50851,O76024,Q9UIG0 12 +Metabolic acidosis 0.2344415412079771 0.0021270206089894 0.9983028843752644 1.0 1.0 56 P07954,Q01968,Q9Y276,P14927,Q9Y2Q9,P23786,Q9HCC0,Q9NX14 8 +Sinus tachycardia 0.2008686210640606 0.0020587296386998 0.9983573725667574 1.0 1.0 9 P50542,O75531,P07954,P06753,P40926,P31040,Q02978,P21912 8 diff --git a/msigdb_hp/selections.json b/msigdb_hp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..73c1fc004a627bef225dff513e854c95a03172aa --- /dev/null +++ b/msigdb_hp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["11 pairs of ribs", "2 3 finger syndactyly", "2 3 toe cutaneous syndactyly", "2 3 toe syndactyly", "3 4 finger syndactyly", "3 methylglutaconic aciduria", "4 5 toe syndactyly", "Abdominal aortic aneurysm", "Abdominal distention", "Abdominal obesity", "Abdominal pain", "Abdominal wall muscle weakness", "Abducens palsy", "Abnormal 2nd finger morphology", "Abnormal 3rd finger morphology", "Abnormal 5th finger morphology", "Abnormal 5th finger phalanx morphology", "Abnormal abdomen morphology", "Abnormal acetabulum morphology", "Abnormal activity of mitochondrial respiratory chain", "Abnormal adipose tissue morphology", "Abnormal aggressive impulsive or violent behavior", "Abnormal aldolase level", "Abnormal anatomic location of the heart", "Abnormal anterior chamber morphology", "Abnormal anterior eye segment morphology", "Abnormal anterior horn cell morphology", "Abnormal aortic arch morphology", "Abnormal aortic morphology", "Abnormal aortic valve cusp morphology", "Abnormal aortic valve morphology", "Abnormal aortic valve physiology", "Abnormal arachnoid mater morphology", "Abnormal arm span", "Abnormal arterial physiology", "Abnormal astrocyte morphology", "Abnormal atrial arrangement", "Abnormal atrioventricular conduction", "Abnormal atrioventricular valve morphology", "Abnormal atrioventricular valve physiology", "Abnormal auditory evoked potentials", "Abnormal autonomic nervous system physiology", "Abnormal b cell morphology", "Abnormal b cell subset distribution", "Abnormal basal ganglia mri signal intensity", "Abnormal biliary tract morphology", "Abnormal bleeding", "Abnormal blistering of the skin", "Abnormal blood carbon dioxide level", "Abnormal blood chloride concentration", "Abnormal blood gas level", "Abnormal blood glucose concentration", "Abnormal blood inorganic cation concentration", "Abnormal blood ion concentration", "Abnormal blood monovalent inorganic cation concentration", "Abnormal blood phosphate concentration", "Abnormal blood potassium concentration", "Abnormal blood sodium concentration", "Abnormal blood transition element cation concentration", "Abnormal blood zinc concentration", "Abnormal bone structure", "Abnormal bowel sounds", "Abnormal brain choline level by mrs", "Abnormal brain lactate level by mrs", "Abnormal brain n acetyl aspartate level by mrs", "Abnormal brain positron emission tomography", "Abnormal brainstem morphology", "Abnormal brainstem mri signal intensity", "Abnormal branching pattern of the aortic arch", "Abnormal breath sound", "Abnormal bronchoalveolar lavage fluid morphology", "Abnormal bronchus morphology", "Abnormal bronchus physiology", "Abnormal c peptide level", "Abnormal c reactive protein level", "Abnormal calcification of the carpal bones", "Abnormal calcium phosphate regulating hormone level", "Abnormal cardiac atrium morphology", "Abnormal cardiac septum morphology", "Abnormal cardiac test", "Abnormal cardiac ventricle morphology", "Abnormal cardiac ventricular function", "Abnormal cardiomyocyte morphology", "Abnormal carotid artery morphology", "Abnormal cartilage morphology", "Abnormal caudate nucleus morphology", "Abnormal cd4 cd8 ratio", "Abnormal cell morphology", "Abnormal cell proliferation", "Abnormal cellular composition of bronchoalveolar fluid", "Abnormal cellular phenotype", "Abnormal central sensory function", "Abnormal cerebellar vermis morphology", "Abnormal cerebral artery morphology", "Abnormal cerebral cortex morphology", "Abnormal cerebral vascular morphology", "Abnormal cerebral vein morphology", "Abnormal cerebral ventricle morphology", "Abnormal cerebrospinal fluid metabolite concentration", "Abnormal cervical curvature", "Abnormal cervical spine morphology", "Abnormal chorioretinal morphology", "Abnormal choroid morphology", "Abnormal choroid plexus morphology", "Abnormal chromosome morphology", "Abnormal ciliary body morphology", "Abnormal circulating acetylcarnitine concentration", "Abnormal circulating albumin concentration", "Abnormal circulating amino acid concentration", "Abnormal circulating amylase level", "Abnormal circulating androgen level", "Abnormal circulating apolipoprotein concentration", "Abnormal circulating arginine concentration", "Abnormal circulating aromatic amino acid concentration", "Abnormal circulating aspartate family amino acid concentration", "Abnormal circulating bilirubin concentration", "Abnormal circulating branched chain amino acid concentration", "Abnormal circulating carbohydrate concentration", "Abnormal circulating carboxylic acid concentration", "Abnormal circulating ceruloplasmin concentration", "Abnormal circulating cholesterol concentration", "Abnormal circulating citrulline concentration", "Abnormal circulating copper concentration", "Abnormal circulating creatinine concentration", "Abnormal circulating dehydroepiandrosterone concentration", "Abnormal circulating dicarboxylic acid concentration", "Abnormal circulating estrogen level", "Abnormal circulating fatty acid anion concentration", "Abnormal circulating fatty acid concentration", "Abnormal circulating ferritin concentration", "Abnormal circulating follicle stimulating hormone concentration", "Abnormal circulating free fatty acid concentration", "Abnormal circulating gaba concentration", "Abnormal circulating glutamine concentration", "Abnormal circulating glutamine family amino acid concentration", "Abnormal circulating glycine concentration", "Abnormal circulating gonadotropin concentration", "Abnormal circulating hormone concentration", "Abnormal circulating iga level", "Abnormal circulating ige level", "Abnormal circulating igg level", "Abnormal circulating igm level", "Abnormal circulating inhibin level", "Abnormal circulating lipid concentration", "Abnormal circulating long chain fatty acid concentration", "Abnormal circulating metabolite concentration", "Abnormal circulating methionine concentration", "Abnormal circulating monocarboxylic acid cocentration", "Abnormal circulating nitrogen compound concentration", "Abnormal circulating non proteinogenic amino acid concentration", "Abnormal circulating nucleobase concentration", "Abnormal circulating phenylalanine concentration", "Abnormal circulating porphyrin concentration", "Abnormal circulating progesterone level", "Abnormal circulating proline concentration", "Abnormal circulating protein concentration", "Abnormal circulating proteinogenic amino acid concentration", "Abnormal circulating proteinogenic amino acid derivative concentration", "Abnormal circulating pyruvate family amino acid concentration", "Abnormal circulating renin", "Abnormal circulating serine concentration", "Abnormal circulating serine family amino acid concentration", "Abnormal circulating sex hormone concentration", "Abnormal circulating sulfur amino acid concentration", "Abnormal circulating tyrosine concentration", "Abnormal clavicle morphology", "Abnormal cns myelination", "Abnormal cochlea morphology", "Abnormal conjugate eye movement", "Abnormal conjunctiva morphology", "Abnormal connection of the cardiac segments", "Abnormal consumption behavior", "Abnormal conus terminalis morphology", "Abnormal cornea morphology", "Abnormal corneal endothelium morphology", "Abnormal corneal epithelium morphology", "Abnormal coronary artery morphology", "Abnormal corpus callosum morphology", "Abnormal corpus striatum morphology", "Abnormal cortical bone morphology", "Abnormal cortical gyration", "Abnormal cranial nerve morphology", "Abnormal cranial nerve physiology", "Abnormal cry", "Abnormal csf carboxylic acid concentration", "Abnormal csf metabolite level", "Abnormal csf protein level", "Abnormal csf pyruvate family amino acid concentration", "Abnormal cutaneous elastic fiber morphology", "Abnormal delayed hypersensitivity skin test", "Abnormal delivery", "Abnormal dense granules", "Abnormal dental pulp morphology", "Abnormal dental root morphology", "Abnormal dentate nucleus morphology", "Abnormal dentin morphology", "Abnormal dermatoglyphics", "Abnormal dermoepidermal junction morphology", "Abnormal descemet membrane morphology", "Abnormal diaphysis morphology", "Abnormal distal phalanx morphology of finger", "Abnormal dlco", "Abnormal drinking behavior", "Abnormal duodenum morphology", "Abnormal dura mater morphology", "Abnormal eating behavior", "Abnormal echocardiogram", "Abnormal elasticity of skin", "Abnormal electrophysiology of sinoatrial node origin", "Abnormal electroretinogram", "Abnormal emotion affect behavior", "Abnormal enchondral ossification", "Abnormal endocardium morphology", "Abnormal endocrine physiology", "Abnormal enzyme coenzyme activity", "Abnormal eosinophil morphology", "Abnormal epidermal morphology", "Abnormal epiglottis morphology", "Abnormal epiphyseal ossification", "Abnormal epiphysis morphology of the phalanges of the hand", "Abnormal erythrocyte enzyme level", "Abnormal erythrocyte morphology", "Abnormal erythrocyte physiology", "Abnormal erythrocyte sedimentation rate", "Abnormal esophagus morphology", "Abnormal esophagus physiology", "Abnormal external genitalia", "Abnormal exteroceptive sensation", "Abnormal eyebrow morphology", "Abnormal eyelash morphology", "Abnormal eyelid morphology", "Abnormal eyelid physiology", "Abnormal facial expression", "Abnormal facial shape", "Abnormal factor ix activity", "Abnormal fallopian tube morphology", "Abnormal fear anxiety related behavior", "Abnormal female reproductive system physiology", "Abnormal femoral head morphology", "Abnormal femoral neck head morphology", "Abnormal femoral neck morphology", "Abnormal finger phalanx morphology", "Abnormal fingernail morphology", "Abnormal fingertip morphology", "Abnormal foot bone ossification", "Abnormal foramen magnum morphology", "Abnormal forearm bone morphology", "Abnormal form of the vertebral bodies", "Abnormal foveal morphology", "Abnormal full field electroretinogram", "Abnormal fundus autofluorescence imaging", "Abnormal gallbladder morphology", "Abnormal gastrointestinal motility", "Abnormal glial cell morphology", "Abnormal globus pallidus morphology", "Abnormal glomerular basement membrane morphology", "Abnormal glomerular filtration rate", "Abnormal glomerular mesangial cellularity", "Abnormal glomerular mesangium morphology", "Abnormal glucose homeostasis", "Abnormal glycosylation", "Abnormal granulocyte count", "Abnormal granulocytopoietic cell morphology", "Abnormal greater sciatic notch morphology", "Abnormal growth hormone level", "Abnormal hair laboratory examination", "Abnormal hair morphology", "Abnormal hair pattern", "Abnormal hair quantity", "Abnormal hair whorl", "Abnormal hand bone ossification", "Abnormal hand morphology", "Abnormal hdl cholesterol concentration", "Abnormal head movements", "Abnormal heart rate variability", "Abnormal heart sound", "Abnormal heart valve morphology", "Abnormal heart valve physiology", "Abnormal hemidiaphragm morphology", "Abnormal hemoglobin", "Abnormal hemoglobin concentration", "Abnormal hepatic iron concentration", "Abnormal humerus morphology", "Abnormal hypothalamus morphology", "Abnormal hypothalamus physiology", "Abnormal ileum morphology", "Abnormal iliac wing morphology", "Abnormal ilium morphology", "Abnormal immune system morphology", "Abnormal incisor morphology", "Abnormal inflammatory response", "Abnormal insulin level", "Abnormal internal genitalia", "Abnormal intestine morphology", "Abnormal intraocular pressure", "Abnormal involuntary eye movements", "Abnormal iris pigmentation", "Abnormal jaw morphology", "Abnormal joint morphology", "Abnormal labia majora morphology", "Abnormal labia minora morphology", "Abnormal labia morphology", "Abnormal lacrimal duct morphology", "Abnormal lacrimal gland morphology", "Abnormal lactate dehydrogenase level", "Abnormal large intestine morphology", "Abnormal large intestine physiology", "Abnormal larynx morphology", "Abnormal larynx physiology", "Abnormal lateral ventricle morphology", "Abnormal ldl cholesterol concentration", "Abnormal left atrium morphology", "Abnormal left ventricle morphology", "Abnormal left ventricular outflow tract morphology", "Abnormal length of corpus callosum", "Abnormal leukocyte count", "Abnormal leukocyte physiology", "Abnormal levels of alpha fetoprotein", "Abnormal libido", "Abnormal light and dark adapted electroretinogram", "Abnormal lip morphology", "Abnormal liver morphology", "Abnormal liver parenchyma morphology", "Abnormal liver physiology", "Abnormal localization of kidney", "Abnormal location of ears", "Abnormal lower limb bone morphology", "Abnormal lower motor neuron morphology", "Abnormal lumbar spine morphology", "Abnormal lung development", "Abnormal lung lobation", "Abnormal lymphatic vessel morphology", "Abnormal lymphocyte morphology", "Abnormal macrophage morphology", "Abnormal macroscopic urine appearance", "Abnormal macular morphology", "Abnormal magnesium concentration", "Abnormal male reproductive system physiology", "Abnormal mandibular ramus morphology", "Abnormal mean corpuscular hemoglobin concentration", "Abnormal mean corpuscular volume", "Abnormal megakaryocyte morphology", "Abnormal meningeal morphology", "Abnormal metabolic brain imaging by mrs", "Abnormal metabolism", "Abnormal metacarpal morphology", "Abnormal metaphyseal trabeculation", "Abnormal metatarsal morphology", "Abnormal midbrain morphology", "Abnormal middle phalanx morphology of the hand", "Abnormal mitochondria in muscle tissue", "Abnormal mitochondrial morphology", "Abnormal mitochondrial number", "Abnormal mitochondrial shape", "Abnormal mitral valve physiology", "Abnormal monocyte morphology", "Abnormal morphology of myocardial trabeculae", "Abnormal morphology of the abdominal musculature", "Abnormal morphology of the choroidal vasculature", "Abnormal morphology of the conjunctival vasculature", "Abnormal morphology of the great vessels", "Abnormal morphology of the limbic system", "Abnormal morphology of the musculature of the neck", "Abnormal morphology of the olfactory bulb", "Abnormal morphology of the radius", "Abnormal motor evoked potentials", "Abnormal motor nerve conduction velocity", "Abnormal muscle fiber alpha dystroglycan", "Abnormal muscle fiber morphology", "Abnormal muscle fiber protein expression", "Abnormal muscle fiber type distribution", "Abnormal muscle glycogen content", "Abnormal myelination", "Abnormal myeloid cell morphology", "Abnormal myeloid leukocyte morphology", "Abnormal myocardium morphology", "Abnormal nasal base", "Abnormal nasal bridge morphology", "Abnormal nasal mucosa morphology", "Abnormal nasolacrimal system morphology", "Abnormal natural killer cell morphology", "Abnormal natural killer cell physiology", "Abnormal nephron morphology", "Abnormal nerve conduction velocity", "Abnormal nervous system electrophysiology", "Abnormal neural tube morphology", "Abnormal neuron morphology", "Abnormal neutrophil count", "Abnormal nipple morphology", "Abnormal number of erythroid precursors", "Abnormal number of granulocyte precursors", "Abnormal number of incisors", "Abnormal number of permanent teeth", "Abnormal number of teeth", "Abnormal odontoid tissue morphology", "Abnormal optical coherence tomography", "Abnormal oral frenulum morphology", "Abnormal oral mucosa morphology", "Abnormal oral physiology", "Abnormal ossification involving the femoral head and neck", "Abnormal ovarian morphology", "Abnormal ovarian physiology", "Abnormal palate morphology", "Abnormal palmar dermatoglyphics", "Abnormal pancreas morphology", "Abnormal pancreas size", "Abnormal paranasal sinus morphology", "Abnormal parietal bone morphology", "Abnormal parotid gland morphology", "Abnormal patella morphology", "Abnormal pattern of respiration", "Abnormal pelvis bone morphology", "Abnormal pelvis bone ossification", "Abnormal penis morphology", "Abnormal pericardium morphology", "Abnormal peripheral action potential amplitude", "Abnormal peripheral myelination", "Abnormal peripheral nervous system morphology", "Abnormal peripheral nervous system physiology", "Abnormal peristalsis", "Abnormal periventricular white matter morphology", "Abnormal phalangeal joint morphology of the hand", "Abnormal pharynx morphology", "Abnormal pigmentation of the oral mucosa", "Abnormal pineal morphology", "Abnormal placenta morphology", "Abnormal placental membrane morphology", "Abnormal placental size", "Abnormal platelet aggregation", "Abnormal platelet function", "Abnormal platelet granules", "Abnormal platelet morphology", "Abnormal platelet volume", "Abnormal pleura morphology", "Abnormal pons morphology", "Abnormal posterior segment imaging", "Abnormal pr interval", "Abnormal preputium morphology", "Abnormal prolactin level", "Abnormal proportion of cd4 positive t cells", "Abnormal proportion of cd8 positive t cells", "Abnormal proportion of class switched memory b cells", "Abnormal proportion of double negative alpha beta regulatory t cell", "Abnormal prostate morphology", "Abnormal protein glycosylation", "Abnormal protein o linked glycosylation", "Abnormal proximal phalanx morphology of the hand", "Abnormal pulmonary interstitial morphology", "Abnormal pulmonary thoracic imaging finding", "Abnormal pulmonary valve morphology", "Abnormal pulmonary valve physiology", "Abnormal pulse", "Abnormal pupil morphology", "Abnormal pupillary function", "Abnormal pupillary light reflex", "Abnormal pyramidal sign", "Abnormal qrs complex", "Abnormal qt interval", "Abnormal rectum morphology", "Abnormal reflex", "Abnormal renal collecting system morphology", "Abnormal renal cortex morphology", "Abnormal renal corticomedullary differentiation", "Abnormal renal echogenicity", "Abnormal renal insterstitial morphology", "Abnormal renal medulla morphology", "Abnormal renal morphology", "Abnormal renal pelvis morphology", "Abnormal renal physiology", "Abnormal renal resorption", "Abnormal renal tubule morphology", "Abnormal renal vascular morphology", "Abnormal respiratory motile cilium morphology", "Abnormal respiratory motile cilium physiology", "Abnormal respiratory system morphology", "Abnormal response to acth stimulation test", "Abnormal response to endocrine stimulation test", "Abnormal response to insulin tolerance test", "Abnormal reticulocyte morphology", "Abnormal retinal artery morphology", "Abnormal retinal morphology", "Abnormal retinal vascular morphology", "Abnormal rib cage morphology", "Abnormal rib ossification", "Abnormal right atrium morphology", "Abnormal right ventricle morphology", "Abnormal right ventricular function", "Abnormal saccadic eye movements", "Abnormal sacroiliac joint morphology", "Abnormal sacrum morphology", "Abnormal salivary gland morphology", "Abnormal sarcomere morphology", "Abnormal scalp morphology", "Abnormal scapula morphology", "Abnormal sclera morphology", "Abnormal scrotal rugation", "Abnormal sella turcica morphology", "Abnormal sensory nerve conduction velocity", "Abnormal serum insulin like growth factor 1 level", "Abnormal serum interferon level", "Abnormal serum interleukin level", "Abnormal serum iron concentration", "Abnormal sex determination", "Abnormal shape of the frontal region", "Abnormal shape of the occiput", "Abnormal shape of the palpebral fissure", "Abnormal sharpey fiber morphology", "Abnormal shoulder morphology", "Abnormal shoulder physiology", "Abnormal size of pituitary gland", "Abnormal size of the clitoris", "Abnormal size of the palpebral fissures", "Abnormal skin morphology of the palm", "Abnormal social behavior", "Abnormal soft palate morphology", "Abnormal speech prosody", "Abnormal sperm motility", "Abnormal spermatogenesis", "Abnormal spinal meningeal morphology", "Abnormal sputum", "Abnormal st segment", "Abnormal sternal ossification", "Abnormal sternum morphology", "Abnormal stomach morphology", "Abnormal stool composition", "Abnormal subarachnoid space morphology", "Abnormal subclavian artery morphology", "Abnormal subcutaneous fat tissue distribution", "Abnormal substantia nigra morphology", "Abnormal superior cerebellar peduncle morphology", "Abnormal sweat gland morphology", "Abnormal synaptic transmission at the neuromuscular junction", "Abnormal systemic arterial morphology", "Abnormal systemic blood pressure", "Abnormal t cell morphology", "Abnormal t cell proliferation", "Abnormal t cell subset distribution", "Abnormal t wave", "Abnormal talus morphology", "Abnormal tarsal ossification", "Abnormal temper tantrums", "Abnormal temporal bone morphology", "Abnormal tendon morphology", "Abnormal testis morphology", "Abnormal thalamic mri signal intensity", "Abnormal thalamic size", "Abnormal thoracic spine morphology", "Abnormal thorax morphology", "Abnormal thrombocyte morphology", "Abnormal thrombosis", "Abnormal thumb morphology", "Abnormal thyroid hormone level", "Abnormal thyroid morphology", "Abnormal thyroid stimulating hormone level", "Abnormal tissue metabolite concentration", "Abnormal toenail morphology", "Abnormal tongue morphology", "Abnormal tongue physiology", "Abnormal trabecular bone morphology", "Abnormal tracheal morphology", "Abnormal tracheobronchial morphology", "Abnormal transferrin saturation", "Abnormal tricuspid valve morphology", "Abnormal tricuspid valve physiology", "Abnormal umbilicus morphology", "Abnormal upper limb bone morphology", "Abnormal upper motor neuron morphology", "Abnormal ureter morphology", "Abnormal ureter physiology", "Abnormal urinary color", "Abnormal urinary electrolyte concentration", "Abnormal urine alpha ketoglutarate concentration", "Abnormal urine carbohydrate level", "Abnormal urine carboxylic acid level", "Abnormal urine cytology", "Abnormal urine hormone level", "Abnormal urine magnesium concentration", "Abnormal urine metabolite level", "Abnormal urine ph", "Abnormal urine phosphate concentration", "Abnormal urine potassium concentration", "Abnormal urine protein level", "Abnormal urine sodium concentration", "Abnormal uterus morphology", "Abnormal uvea morphology", "Abnormal uvula morphology", "Abnormal vagina morphology", "Abnormal vascular morphology", "Abnormal vascular physiology", "Abnormal vena cava morphology", "Abnormal venous morphology", "Abnormal ventricular septum morphology", "Abnormal vertebral morphology", "Abnormal vertebral segmentation and fusion", "Abnormal vestibulo ocular reflex", "Abnormal visual electrophysiology", "Abnormal visual field test", "Abnormal visual fixation", "Abnormal vitamin b12 level", "Abnormal vitreous humor morphology", "Abnormal waist to hip ratio", "Abnormal z disc morphology", "Abnormalities of placenta or umbilical cord", "Abnormality iris morphology", "Abnormality of abdominal situs", "Abnormality of acid base homeostasis", "Abnormality of adrenal morphology", "Abnormality of adrenal physiology", "Abnormality of alkaline phosphatase level", "Abnormality of amino acid metabolism", "Abnormality of bladder morphology", "Abnormality of blood circulation", "Abnormality of blood volume homeostasis", "Abnormality of body mass index", "Abnormality of bone marrow cell morphology", "Abnormality of bone mineral density", "Abnormality of canine", "Abnormality of cardiovascular system electrophysiology", "Abnormality of carpal bone ossification", "Abnormality of cartilage of external ear", "Abnormality of central nervous system electrophysiology", "Abnormality of chorioretinal pigmentation", "Abnormality of chromosome segregation", "Abnormality of chromosome stability", "Abnormality of circulating adrenocorticotropin level", "Abnormality of circulating enzyme level", "Abnormality of circulating fibrinogen", "Abnormality of circulating glucocorticoid level", "Abnormality of circulating leptin level", "Abnormality of coagulation", "Abnormality of complement system", "Abnormality of coordination", "Abnormality of corneal size", "Abnormality of corneal stroma", "Abnormality of corneal thickness", "Abnormality of cranial sutures", "Abnormality of dental color", "Abnormality of dental eruption", "Abnormality of dental morphology", "Abnormality of dental structure", "Abnormality of dermal melanosomes", "Abnormality of digestive system morphology", "Abnormality of dna repair", "Abnormality of earlobe", "Abnormality of endocrine pancreas physiology", "Abnormality of epiphysis morphology", "Abnormality of exocrine pancreas physiology", "Abnormality of extrapyramidal motor function", "Abnormality of facial adipose tissue", "Abnormality of facial musculature", "Abnormality of facial skeleton", "Abnormality of facial soft tissue", "Abnormality of female external genitalia", "Abnormality of femur morphology", "Abnormality of fibula morphology", "Abnormality of finger", "Abnormality of fluid regulation", "Abnormality of folate metabolism", "Abnormality of fontanelles", "Abnormality of foveal pigmentation", "Abnormality of frontal sinus", "Abnormality of frontalis muscle belly", "Abnormality of fundus pigmentation", "Abnormality of globe location", "Abnormality of globe size", "Abnormality of glycolipid metabolism", "Abnormality of hair growth", "Abnormality of hair pigmentation", "Abnormality of hair texture", "Abnormality of hand joint mobility", "Abnormality of head blood vessel", "Abnormality of hepatobiliary system physiology", "Abnormality of hindbrain morphology", "Abnormality of humoral immunity", "Abnormality of immune serum protein physiology", "Abnormality of iron homeostasis", "Abnormality of krebs cycle metabolism", "Abnormality of lens shape", "Abnormality of limb epiphysis morphology", "Abnormality of lipoprotein cholesterol concentration", "Abnormality of long bone morphology", "Abnormality of lower limb epiphysis morphology", "Abnormality of lower limb joint", "Abnormality of lower limb metaphyses", "Abnormality of lower lip", "Abnormality of lysosomal metabolism", "Abnormality of macular pigmentation", "Abnormality of malar bones", "Abnormality of male internal genitalia", "Abnormality of metacarpal epiphyses", "Abnormality of metacarpophalangeal joint", "Abnormality of mouth shape", "Abnormality of mouth size", "Abnormality of muscle size", "Abnormality of nail color", "Abnormality of neuronal migration", "Abnormality of neutrophil morphology", "Abnormality of neutrophil physiology", "Abnormality of neutrophils", "Abnormality of ocular smooth pursuit", "Abnormality of pain sensation", "Abnormality of pancreas physiology", "Abnormality of pelvic girdle bone morphology", "Abnormality of periauricular region", "Abnormality of peripheral nerves", "Abnormality of prenatal development or birth", "Abnormality of primary teeth", "Abnormality of prothrombin", "Abnormality of pulmonary circulation", "Abnormality of refraction", "Abnormality of renal excretion", "Abnormality of renin angiotensin system", "Abnormality of reproductive system physiology", "Abnormality of retinal pigmentation", "Abnormality of salivation", "Abnormality of secondary sexual hair", "Abnormality of skeletal maturation", "Abnormality of skeletal muscle fiber size", "Abnormality of skin adnexa physiology", "Abnormality of skin physiology", "Abnormality of skin pigmentation", "Abnormality of skull ossification", "Abnormality of small intestinal villus morphology", "Abnormality of somatosensory evoked potentials", "Abnormality of subcutaneous fat tissue", "Abnormality of t cell physiology", "Abnormality of taste sensation", "Abnormality of temperature regulation", "Abnormality of thalamus morphology", "Abnormality of the 1st metacarpal", "Abnormality of the 2nd toe", "Abnormality of the 3rd toe", "Abnormality of the 4th metacarpal", "Abnormality of the 5th metacarpal", "Abnormality of the 5th toe", "Abnormality of the abdominal organs", "Abnormality of the abdominal wall", "Abnormality of the achilles tendon", "Abnormality of the adrenal glands", "Abnormality of the alveolar ridges", "Abnormality of the amniotic fluid", "Abnormality of the ankles", "Abnormality of the anterior fontanelle", "Abnormality of the antihelix", "Abnormality of the antitragus", "Abnormality of the anus", "Abnormality of the auditory canal", "Abnormality of the autonomic nervous system", "Abnormality of the axillary hair", "Abnormality of the basal ganglia", "Abnormality of the biliary system", "Abnormality of the bladder", "Abnormality of the brainstem white matter", "Abnormality of the breast", "Abnormality of the calcaneus", "Abnormality of the calf", "Abnormality of the calf musculature", "Abnormality of the calvaria", "Abnormality of the carpal bones", "Abnormality of the cerebral subcortex", "Abnormality of the cerebrospinal fluid", "Abnormality of the cervical spine", "Abnormality of the cheek", "Abnormality of the chin", "Abnormality of the choanae", "Abnormality of the clitoris", "Abnormality of the coagulation cascade", "Abnormality of the columella", "Abnormality of the common coagulation pathway", "Abnormality of the costochondral junction", "Abnormality of the crus of the helix", "Abnormality of the curvature of the cornea", "Abnormality of the curvature of the vertebral column", "Abnormality of the dentition", "Abnormality of the diaphragm", "Abnormality of the diencephalon", "Abnormality of the distal phalanges of the toes", "Abnormality of the distal phalanx of the hallux", "Abnormality of the distal phalanx of the thumb", "Abnormality of the dorsal column of the spinal cord", "Abnormality of the elbow", "Abnormality of the endometrium", "Abnormality of the epididymis", "Abnormality of the epiphyses of the distal phalanx of finger", "Abnormality of the external nose", "Abnormality of the extraocular muscles", "Abnormality of the extrinsic pathway", "Abnormality of the female genitalia", "Abnormality of the fetal cardiovascular system", "Abnormality of the fifth metatarsal bone", "Abnormality of the first metatarsal bone", "Abnormality of the fontanelles or cranial sutures", "Abnormality of the foot musculature", "Abnormality of the forearm", "Abnormality of the forehead", "Abnormality of the frontal hairline", "Abnormality of the gallbladder", "Abnormality of the gastric mucosa", "Abnormality of the gingiva", "Abnormality of the glabella", "Abnormality of the glenoid fossa", "Abnormality of the hairline", "Abnormality of the hallux", "Abnormality of the helix", "Abnormality of the hepatic vasculature", "Abnormality of the humeroradial joint", "Abnormality of the humerus", "Abnormality of the hypothalamus pituitary axis", "Abnormality of the hypothenar eminence", "Abnormality of the incisor", "Abnormality of the inner ear", "Abnormality of the internal auditory canal", "Abnormality of the intervertebral disk", "Abnormality of the intrahepatic bile duct", "Abnormality of the intrinsic pathway", "Abnormality of the kidney", "Abnormality of the knee", "Abnormality of the larynx", "Abnormality of the lens", "Abnormality of the leydig cells", "Abnormality of the liver", "Abnormality of the lower urinary tract", "Abnormality of the lymph nodes", "Abnormality of the lymphatic system", "Abnormality of the mastoid", "Abnormality of the maxilla", "Abnormality of the menstrual cycle", "Abnormality of the metacarpal bones", "Abnormality of the metaphysis", "Abnormality of the metopic suture", "Abnormality of the middle ear", "Abnormality of the middle ear ossicles", "Abnormality of the middle phalanges of the toes", "Abnormality of the middle phalanx of the 5th finger", "Abnormality of the midface", "Abnormality of the mitochondrion", "Abnormality of the musculature of the hand", "Abnormality of the musculature of the limbs", "Abnormality of the musculature of the lower limbs", "Abnormality of the musculature of the thigh", "Abnormality of the musculature of the upper arm", "Abnormality of the musculature of the upper limbs", "Abnormality of the nail", "Abnormality of the nasal alae", "Abnormality of the nasal bone", "Abnormality of the nasal cavity", "Abnormality of the nasal dorsum", "Abnormality of the nasal septum", "Abnormality of the nasal skeleton", "Abnormality of the nasal tip", "Abnormality of the nasolabial region", "Abnormality of the neck", "Abnormality of the odontoid process", "Abnormality of the optic nerve", "Abnormality of the outer ear", "Abnormality of the ovary", "Abnormality of the palm", "Abnormality of the palpebral fissures", "Abnormality of the pancreas", "Abnormality of the parathyroid gland", "Abnormality of the parathyroid morphology", "Abnormality of the periorbital region", "Abnormality of the peripheral nervous system", "Abnormality of the peritoneum", "Abnormality of the periungual region", "Abnormality of the phalanges of the hallux", "Abnormality of the phalanges of the toes", "Abnormality of the pharynx", "Abnormality of the philtrum", "Abnormality of the pineal gland", "Abnormality of the pinna", "Abnormality of the pituitary gland", "Abnormality of the plantar skin of foot", "Abnormality of the posterior pituitary", "Abnormality of the protein c anticoagulant pathway", "Abnormality of the proximal phalanx of the thumb", "Abnormality of the pubic bone", "Abnormality of the pubic hair", "Abnormality of the pulmonary artery", "Abnormality of the pulmonary vasculature", "Abnormality of the pulmonary veins", "Abnormality of the pylorus", "Abnormality of the radial head", "Abnormality of the radioulnar joints", "Abnormality of the ribs", "Abnormality of the scrotum", "Abnormality of the sense of smell", "Abnormality of the septum pellucidum", "Abnormality of the shoulder girdle musculature", "Abnormality of the skull base", "Abnormality of the small intestine", "Abnormality of the spinal cord", "Abnormality of the spleen", "Abnormality of the stapes", "Abnormality of the subungual region", "Abnormality of the supraorbital ridges", "Abnormality of the synovia", "Abnormality of the tarsal bones", "Abnormality of the temporomandibular joint", "Abnormality of the testis size", "Abnormality of the thenar eminence", "Abnormality of the thoracic cavity", "Abnormality of the thymus", "Abnormality of the thyroid gland", "Abnormality of the tongue", "Abnormality of the tongue muscle", "Abnormality of the tonsils", "Abnormality of the tragus", "Abnormality of the ulna", "Abnormality of the umbilical cord", "Abnormality of the upper arm", "Abnormality of the upper respiratory tract", "Abnormality of the ureter", "Abnormality of the urethra", "Abnormality of the urinary system physiology", "Abnormality of the uterus", "Abnormality of the vasculature of the eye", "Abnormality of the vertebral endplates", "Abnormality of the vestibulocochlear nerve", "Abnormality of the voice", "Abnormality of the wrist", "Abnormality of the zygomatic bone", "Abnormality of thyroid physiology", "Abnormality of tibia morphology", "Abnormality of toe", "Abnormality of ulnar metaphysis", "Abnormality of upper limb epiphysis morphology", "Abnormality of upper limb joint", "Abnormality of upper limb metaphysis", "Abnormality of upper lip", "Abnormality of upper lip vermillion", "Abnormality of urinary uric acid concentration", "Abnormality of urine calcium concentration", "Abnormality of urine catecholamine concentration", "Abnormality of urine homeostasis", "Abnormality of visual evoked potentials", "Abnormality of vitamin a metabolism", "Abnormality of vitamin b metabolism", "Abnormality of vitamin b12 metabolism", "Abnormality of vitamin d metabolism", "Abnormality of vitamin e metabolism", "Abnormality of vitamin k metabolism", "Abnormality of vitamin metabolism", "Abnormality on pulmonary function testing", "Abnormally folded helix", "Abnormally large globe", "Abnormally lax or hyperextensible skin", "Abnormally low pitched voice", "Abnormally ossified vertebrae", "Abnormally shaped carpal bones", "Abscess", "Absence of pubertal development", "Absence of secondary sex characteristics", "Absence of subcutaneous fat", "Absent axillary hair", "Absent brainstem auditory responses", "Absent distal phalanges", "Absent earlobe", "Absent epiphyses", "Absent eyebrow", "Absent facial hair", "Absent fingernail", "Absent forearm bone", "Absent foveal reflex", "Absent frontal sinuses", "Absent hair", "Absent hypoplastic paranasal sinuses", "Absent nares", "Absent nipple", "Absent or minimally ossified vertebral bodies", "Absent outer dynein arms", "Absent palmar crease", "Absent septum pellucidum", "Absent shortened dynein arms", "Absent speech", "Absent sternal ossification", "Absent testis", "Absent thumb", "Absent thumbnail", "Absent toe", "Absent toenail", "Acanthocytosis", "Acantholysis", "Acanthosis nigricans", "Accelerated atherosclerosis", "Accelerated skeletal maturation", "Accessory oral frenulum", "Accessory spleen", "Acetabular dysplasia", "Achilles tendon contracture", "Acidemia", "Acne", "Acne inversa", "Acquired abnormal hair pattern", "Acral blistering", "Acral ulceration", "Acromesomelia", "Acromicria", "Action tremor", "Acute coronary syndrome", "Acute encephalopathy", "Acute hepatic failure", "Acute kidney injury", "Acute leukemia", "Acute lymphoblastic leukemia", "Acute myeloid leukemia", "Acute pancreatitis", "Acute phase response", "Addictive behavior", "Adducted thumb", "Adenocarcinoma of the colon", "Adenocarcinoma of the intestines", "Adenocarcinoma of the small intestine", "Adenoma sebaceum", "Adenomatous colonic polyposis", "Adipose tissue loss", "Adrenal hyperplasia", "Adrenal hypoplasia", "Adrenal insufficiency", "Adrenal overactivity", "Adrenocortical abnormality", "Adrenocortical carcinoma", "Adrenocorticotropic hormone deficiency", "Adrenocorticotropic hormone excess", "Adrenocorticotropin deficient adrenal insufficiency", "Adult onset", "Advanced eruption of teeth", "Agammaglobulinemia", "Aganglionic megacolon", "Agenesis of central incisor", "Agenesis of cerebellar vermis", "Agenesis of corpus callosum", "Agenesis of incisor", "Agenesis of lateral incisor", "Agenesis of maxillary incisor", "Agenesis of permanent teeth", "Aggressive behavior", "Agitation", "Agnosia", "Agyria", "Airway obstruction", "Akinesia", "Alacrima", "Albinism", "Albuminuria", "Alexia", "Alkalosis", "Allergic rhinitis", "Allergy", "Alopecia", "Alopecia of scalp", "Alopecia totalis", "Alopecia universalis", "Alternating esotropia", "Alveolar cell carcinoma", "Alveolar rhabdomyosarcoma", "Alveolar ridge overgrowth", "Amaurosis fugax", "Ambiguous genitalia", "Ambiguous genitalia female", "Ambiguous genitalia male", "Amblyopia", "Amegakaryocytic thrombocytopenia", "Amenorrhea", "Aminoaciduria", "Amniotic constriction ring", "Amyloidosis", "Amyotrophic lateral sclerosis", "Anal atresia", "Anal stenosis", "Anarthria", "Anasarca", "Anemia of inadequate production", "Anemic pallor", "Anencephaly", "Angina pectoris", "Angioedema", "Angiofibromas", "Angioid streaks of the fundus", "Angiokeratoma", "Angular cheilitis", "Anhidrosis", "Aniridia", "Anisocoria", "Anisocytosis", "Anisopoikilocytosis", "Anisospondyly", "Ankle clonus", "Ankle flexion contracture", "Ankle weakness", "Ankyloblepharon", "Ankyloglossia", "Ankylosis", "Annular pancreas", "Anodontia", "Anomalous trichromacy", "Anonychia", "Anophthalmia", "Anorectal anomaly", "Anorexia", "Anosmia", "Anotia", "Antenatal onset", "Anterior chamber synechiae", "Anterior open bite malocclusion", "Anterior pituitary dysgenesis", "Anterior plagiocephaly", "Anterior rib cupping", "Anterior synechiae of the anterior chamber", "Anterior uveitis", "Anteriorly placed anus", "Anteverted ears", "Anti thyroid peroxidase antibody positivity", "Antineutrophil antibody positivity", "Antinuclear antibody positivity", "Antiphospholipid antibody positivity", "Aortic aneurysm", "Aortic arch aneurysm", "Aortic atherosclerotic lesion", "Aortic dissection", "Aortic regurgitation", "Aortic root aneurysm", "Aortic valve calcification", "Aortic valve stenosis", "Aphasia", "Aphthous ulcer", "Aplasia cutis congenita", "Aplasia cutis congenita of scalp", "Aplasia cutis congenita on trunk or limbs", "Aplasia cutis congenita over the scalp vertex", "Aplasia hypoplasia affecting bones of the axial skeleton", "Aplasia hypoplasia affecting the anterior segment of the eye", "Aplasia hypoplasia affecting the eye", "Aplasia hypoplasia affecting the fundus", "Aplasia hypoplasia involving bones of the feet", "Aplasia hypoplasia involving bones of the lower limbs", "Aplasia hypoplasia involving bones of the thorax", "Aplasia hypoplasia involving bones of the upper limbs", "Aplasia hypoplasia involving forearm bones", "Aplasia hypoplasia involving the carpal bones", "Aplasia hypoplasia involving the femoral head and neck", "Aplasia hypoplasia involving the metacarpal bones", "Aplasia hypoplasia involving the musculature of the upper limbs", "Aplasia hypoplasia involving the nose", "Aplasia hypoplasia involving the pelvis", "Aplasia hypoplasia involving the sinuses", "Aplasia hypoplasia involving the skeletal musculature", "Aplasia hypoplasia involving the skeleton", "Aplasia hypoplasia involving the vertebral column", "Aplasia hypoplasia of fingers", "Aplasia hypoplasia of metatarsal bones", "Aplasia hypoplasia of the 4th metacarpal", "Aplasia hypoplasia of the 5th finger", "Aplasia hypoplasia of the 5th metacarpal", "Aplasia hypoplasia of the abdominal wall musculature", "Aplasia hypoplasia of the bladder", "Aplasia hypoplasia of the breasts", "Aplasia hypoplasia of the capital femoral epiphysis", "Aplasia hypoplasia of the cerebellar vermis", "Aplasia hypoplasia of the cerebellum", "Aplasia hypoplasia of the cerebral white matter", "Aplasia hypoplasia of the clavicles", "Aplasia hypoplasia of the colon", "Aplasia hypoplasia of the distal phalanges of the hand", "Aplasia hypoplasia of the distal phalanges of the toes", "Aplasia hypoplasia of the distal phalanx of the thumb", "Aplasia hypoplasia of the ear", "Aplasia hypoplasia of the earlobes", "Aplasia hypoplasia of the epiglottis", "Aplasia hypoplasia of the extremities", "Aplasia hypoplasia of the eyebrow", "Aplasia hypoplasia of the eyelid", "Aplasia hypoplasia of the femur", "Aplasia hypoplasia of the fibula", "Aplasia hypoplasia of the gallbladder", "Aplasia hypoplasia of the hallux", "Aplasia hypoplasia of the humerus", "Aplasia hypoplasia of the lungs", "Aplasia hypoplasia of the middle phalanges of the toes", "Aplasia hypoplasia of the nails", "Aplasia hypoplasia of the nasal bone", "Aplasia hypoplasia of the nasal septum", "Aplasia hypoplasia of the nipples", "Aplasia hypoplasia of the optic nerve", "Aplasia hypoplasia of the ovary", "Aplasia hypoplasia of the palmar creases", "Aplasia hypoplasia of the patella", "Aplasia hypoplasia of the phalanges of the hallux", "Aplasia hypoplasia of the phalanges of the hand", "Aplasia hypoplasia of the phalanges of the thumb", "Aplasia hypoplasia of the phalanges of the toes", "Aplasia hypoplasia of the proximal phalanges of the hand", "Aplasia hypoplasia of the pubic bone", "Aplasia hypoplasia of the radius", "Aplasia hypoplasia of the retina", "Aplasia hypoplasia of the ribs", "Aplasia hypoplasia of the sacrum", "Aplasia hypoplasia of the scapulae", "Aplasia hypoplasia of the skin", "Aplasia hypoplasia of the spleen", "Aplasia hypoplasia of the sternum", "Aplasia hypoplasia of the thumb", "Aplasia hypoplasia of the thymus", "Aplasia hypoplasia of the thyroid gland", "Aplasia hypoplasia of the tibia", "Aplasia hypoplasia of the tongue", "Aplasia hypoplasia of the tragus", "Aplasia hypoplasia of the ulna", "Aplasia hypoplasia of the uterus", "Aplasia hypoplasia of the uvula", "Aplasia hypoplasia of the vagina", "Aplasia hypoplasia of toe", "Aplasia involving bones of the extremities", "Aplasia involving bones of the lower limbs", "Aplasia of metacarpal bones", "Aplasia of the fingers", "Aplasia of the middle phalanx of the hand", "Aplasia of the phalanges of the hand", "Aplasia of the phalanges of the toes", "Aplasia of the proximal phalanges of the hand", "Aplasia of the semicircular canal", "Aplasia of the uterus", "Aplastic anemia", "Aplastic clavicle", "Aplastic hypoplastic lacrimal glands", "Aplastic hypoplastic toenail", "Apnea", "Apneic episodes in infancy", "Apneic episodes precipitated by illness fatigue stress", "Appendicular hypotonia", "Apraxia", "Aqueductal stenosis", "Arachnodactyly", "Arachnoid hemangiomatosis", "Areflexia", "Areflexia of lower limbs", "Arm dystonia", "Arnold chiari malformation", "Arnold chiari type i malformation", "Arrhinencephaly", "Arteria lusoria", "Arterial dissection", "Arterial rupture", "Arterial stenosis", "Arterial thrombosis", "Arteriosclerosis", "Arteriovenous fistula", "Arteriovenous malformation", "Arthralgia", "Arthritis", "Arthrogryposis multiplex congenita", "Arthropathy", "Ascending aortic dissection", "Ascending tubular aorta aneurysm", "Ascites", "Aspiration", "Aspiration pneumonia", "Asterixis", "Asthenia", "Asthma", "Astigmatism", "Astrocytoma", "Astrocytosis", "Asymmetric growth", "Asymmetric septal hypertrophy", "Asymmetry of the ears", "Asymmetry of the thorax", "Atelectasis", "Athetosis", "Atlantoaxial abnormality", "Atlantoaxial dislocation", "Atlantoaxial instability", "Atonic seizure", "Atopic dermatitis", "Atresia of the external auditory canal", "Atrial arrhythmia", "Atrial flutter", "Atrioventricular canal defect", "Atrophic scars", "Atrophy degeneration affecting the brainstem", "Atrophy degeneration affecting the central nervous system", "Atrophy degeneration affecting the cerebrum", "Atrophy degeneration involving the caudate nucleus", "Atrophy degeneration involving the corticospinal tracts", "Atrophy degeneration involving the spinal cord", "Atrophy of alveolar ridges", "Attention deficit hyperactivity disorder", "Attenuation of retinal blood vessels", "Atypical absence seizure", "Auditory hallucinations", "Autism", "Autistic behavior", "Autoamputation", "Autoamputation of digits", "Autoimmune antibody positivity", "Autoimmune hemolytic anemia", "Autoimmune thrombocytopenia", "Autoimmunity", "Autophagic vacuoles", "Autosomal dominant germline de novo mutation", "Avascular necrosis", "Avascular necrosis of the capital femoral epiphysis", "Axial dystonia", "Axial muscle weakness", "Axillary pterygium", "Axonal degeneration", "Axonal degeneration regeneration", "Axonal loss", "Axonal regeneration", "Azoospermia", "B cell lymphoma", "B lymphocytopenia", "Babinski sign", "Back pain", "Bacterial endocarditis", "Barrel shaped chest", "Barrett esophagus", "Basal cell carcinoma", "Basal ganglia calcification", "Basal ganglia cysts", "Basal ganglia gliosis", "Beaded ribs", "Beaking of vertebral bodies", "Bell shaped thorax", "Benign neoplasm of the central nervous system", "Bicarbonaturia", "Biconcave vertebral bodies", "Bicornuate uterus", "Bicoronal synostosis", "Bifid nasal tip", "Bifid ribs", "Bifid scrotum", "Bifid tongue", "Bifid uterus", "Bifid uvula", "Bilateral cleft lip", "Bilateral cleft lip and palate", "Bilateral cleft palate", "Bilateral coxa valga", "Bilateral cryptorchidism", "Bilateral external ear deformity", "Bilateral microphthalmos", "Bilateral polymicrogyria", "Bilateral ptosis", "Bilateral sensorineural hearing impairment", "Bilateral single transverse palmar creases", "Bilateral talipes equinovarus", "Bilateral tonic clonic seizure", "Bilateral tonic clonic seizure with focal onset", "Bilateral tonic clonic seizure with generalized onset", "Bile duct proliferation", "Biliary atresia", "Biliary cirrhosis", "Biliary tract abnormality", "Biliary tract neoplasm", "Bimanual synkinesia", "Biparietal narrowing", "Bird like facies", "Birth length greater than 97th percentile", "Birth length less than 3rd percentile", "Biventricular hypertrophy", "Bladder diverticulum", "Bladder neoplasm", "Bleeding with minor or no trauma", "Blepharitis", "Blepharophimosis", "Blindness", "Blistering by anatomical location", "Blistering by histological location", "Bloodstream infectious agent", "Bloody diarrhea", "Blue irides", "Blue nevus", "Blue sclerae", "Blurred vision", "Bone cyst", "Bone fracture", "Bone marrow foam cells", "Bone marrow hypercellularity", "Bone marrow hypocellularity", "Bone pain", "Bone spicule pigmentation of the retina", "Bowel diverticulosis", "Bowing of the arm", "Bowing of the legs", "Brachycephaly", "Brachydactyly", "Brachyturricephaly", "Bradycardia", "Bradykinesia", "Brain imaging abnormality", "Brain neoplasm", "Brain stem compression", "Branchial anomaly", "Branchial cyst", "Branchial fistula", "Breast aplasia", "Breast carcinoma", "Breast hypoplasia", "Breathing dysregulation", "Breech presentation", "Brisk reflexes", "Brittle hair", "Broad alveolar ridges", "Broad based gait", "Broad chin", "Broad clavicles", "Broad columella", "Broad distal phalanx of finger", "Broad eyebrow", "Broad face", "Broad femoral neck", "Broad finger", "Broad foot", "Broad forehead", "Broad hallux phalanx", "Broad jaw", "Broad long bones", "Broad metacarpals", "Broad nail", "Broad nasal tip", "Broad neck", "Broad palm", "Broad phalanx of the toes", "Broad philtrum", "Broad ribs", "Broad thumb", "Broad toe", "Bronchiectasis", "Bronchitis", "Bronchomalacia", "Bronchospasm", "Bruising susceptibility", "Brushfield spots", "Bruxism", "Bulbar palsy", "Bulbar signs", "Bulbous nose", "Bull s eye maculopathy", "Bundle branch block", "Buphthalmos", "Burkitt lymphoma", "Butterfly vertebrae", "Cachexia", "Caesarian section", "Cafe au lait spot", "Calcific stippling", "Calcification of cartilage", "Calcification of the aorta", "Calcinosis", "Calcium nephrolithiasis", "Calcium oxalate nephrolithiasis", "Calf muscle pseudohypertrophy", "Calvarial hyperostosis", "Calvarial osteosclerosis", "Calvarial skull defect", "Camptodactyly of toe", "Capillary hemangioma", "Capillary malformation", "Capitate hamate fusion", "Carcinoid tumor", "Carcinoma", "Cardiac arrest", "Cardiac conduction abnormality", "Cardiac diverticulum", "Cardiac rhabdomyoma", "Cardiac valve calcification", "Cardiomegaly", "Cardiorespiratory arrest", "Cardiovascular calcification", "Carious teeth", "Carpal bone hypoplasia", "Carpal synostosis", "Cataplexy", "Caudate atrophy", "Cavernous hemangioma", "Cavum septum pellucidum", "Celiac disease", "Cellular immunodeficiency", "Cellulitis", "Central adrenal insufficiency", "Central apnea", "Central diabetes insipidus", "Central heterochromia", "Central hypothyroidism", "Central hypoventilation", "Central nervous system cyst", "Central opacification of the cornea", "Central primitive neuroectodermal tumor", "Central scotoma", "Central sleep apnea", "Central y shaped metacarpal", "Centrally nucleated skeletal muscle fibers", "Centrocecal scotoma", "Cerebellar atrophy", "Cerebellar cortical atrophy", "Cerebellar cyst", "Cerebellar dysplasia", "Cerebellar hemorrhage", "Cerebellar hypoplasia", "Cerebellar malformation", "Cerebellar vermis atrophy", "Cerebral arteriovenous malformation", "Cerebral calcification", "Cerebral cortical atrophy", "Cerebral cortical hemiatrophy", "Cerebral dysmyelination", "Cerebral edema", "Cerebral hamartoma", "Cerebral hemorrhage", "Cerebral hypomyelination", "Cerebral hypoplasia", "Cerebral inclusion bodies", "Cerebral palsy", "Cerebral venous thrombosis", "Cerebral visual impairment", "Cerebral white matter atrophy", "Cerebral white matter hypoplasia", "Cervical kyphosis", "Cervical myelopathy", "Cervical ribs", "Cervical spinal canal stenosis", "Cervical spine instability", "Cervical subluxation", "Cessation of head growth", "Cheilitis", "Cherry red spot of the macula", "Chest pain", "Chilblains", "Childhood onset", "Childhood onset sensorineural hearing impairment", "Childhood onset truncal obesity", "Chills", "Choanal stenosis", "Choking episodes", "Cholangiocarcinoma", "Cholangitis", "Cholecystitis", "Cholestasis", "Cholestatic liver disease", "Chondrocalcinosis", "Chondrosarcoma", "Chordee", "Chorea", "Choreoathetosis", "Choriocarcinoma", "Chorioretinal atrophy", "Chorioretinal coloboma", "Chorioretinal degeneration", "Chorioretinal dysplasia", "Chorioretinal dystrophy", "Chorioretinal hypopigmentation", "Choroid plexus carcinoma", "Choroid plexus cyst", "Choroidal melanoma", "Choroidal neovascularization", "Chromosomal breakage induced by crosslinking agents", "Chromosomal breakage induced by ionizing radiation", "Chromosome breakage", "Chronic atrophic gastritis", "Chronic axonal neuropathy", "Chronic bronchitis", "Chronic constipation", "Chronic diarrhea", "Chronic fatigue", "Chronic hemolytic anemia", "Chronic hepatic failure", "Chronic infection", "Chronic kidney disease", "Chronic leukemia", "Chronic lung disease", "Chronic lymphatic leukemia", "Chronic mucocutaneous candidiasis", "Chronic neutropenia", "Chronic noninfectious lymphadenopathy", "Chronic oral candidiasis", "Chronic otitis media", "Chronic pulmonary obstruction", "Chronic rhinitis", "Chronic sinusitis", "Chylothorax", "Cigarette paper scars", "Cirrhosis", "Cleft hard palate", "Cleft lip", "Cleft soft palate", "Cleft upper lip", "Clinodactyly", "Clitoral hypoplasia", "Clonic seizure", "Clonus", "Cloverleaf skull", "Clubbing", "Clubbing of fingers", "Clubbing of toes", "Clumsiness", "Cns demyelination", "Cns hypomyelination", "Coarctation of aorta", "Coarse facial features", "Coarse hair", "Cochlear malformation", "Cognitive impairment", "Cogwheel rigidity", "Cold induced muscle cramps", "Colitis", "Collectionism", "Coloboma", "Colon cancer", "Color vision defect", "Color vision test abnormality", "Colorectal polyposis", "Colpocephaly", "Coma", "Combined immunodeficiency", "Communicating hydrocephalus", "Complete atrioventricular canal defect", "Complete duplication of phalanx of hand", "Complex febrile seizure", "Concave nail", "Concave nasal ridge", "Concentric hypertrophic cardiomyopathy", "Cone cone rod dystrophy", "Cone shaped epiphyses of the phalanges of the hand", "Cone shaped epiphysis", "Confetti like hypopigmented macules", "Confusion", "Congenital adrenal hyperplasia", "Congenital bilateral hip dislocation", "Congenital blindness", "Congenital contracture", "Congenital craniofacial dysostosis", "Congenital diaphragmatic hernia", "Congenital hemolytic anemia", "Congenital hepatic fibrosis", "Congenital hip dislocation", "Congenital hypothyroidism", "Congenital ichthyosiform erythroderma", "Congenital localized absence of skin", "Congenital malformation of the great arteries", "Congenital malformation of the left heart", "Congenital malformation of the right heart", "Congenital muscular dystrophy", "Congenital muscular torticollis", "Congenital nonbullous ichthyosiform erythroderma", "Congenital nystagmus", "Congenital onset", "Congenital posterior urethral valve", "Congenital sensorineural hearing impairment", "Congenital stationary night blindness", "Congenital thrombocytopenia", "Congestive heart failure", "Conical tooth", "Conjugated hyperbilirubinemia", "Conjunctival hamartoma", "Connective tissue nevi", "Conspicuously happy disposition", "Constipation", "Constitutional symptom", "Constriction of peripheral visual field", "Contiguous gene syndrome", "Contractures involving the joints of the feet", "Contractures of the joints of the lower limbs", "Contractures of the joints of the upper limbs", "Contractures of the large joints", "Convex nasal ridge", "Coombs positive hemolytic anemia", "Cor pulmonale", "Corneal dystrophy", "Corneal erosion", "Corneal neovascularization", "Corneal opacity", "Corneal scarring", "Corneal ulceration", "Coronal cleft vertebrae", "Coronal craniosynostosis", "Coronary artery atherosclerosis", "Corpus callosum atrophy", "Cortical cataract", "Cortical dysplasia", "Cortical myoclonus", "Cortical thickening of long bone diaphyses", "Corticospinal tract hypoplasia", "Cough", "Coxa valga", "Coxa vara", "Crackles", "Cranial asymmetry", "Cranial hyperostosis", "Cranial nerve compression", "Craniofacial asymmetry", "Craniofacial dysostosis", "Craniofacial hyperostosis", "Craniofacial osteosclerosis", "Craniosynostosis", "Crumpled long bones", "Cryptorchidism", "Csf lymphocytic pleiocytosis", "Csf pleocytosis", "Cubitus valgus", "Cupped ear", "Cupped ribs", "Curly eyelashes", "Curly hair", "Cutaneous abscess", "Cutaneous amyloidosis", "Cutaneous cyst", "Cutaneous finger syndactyly", "Cutaneous melanoma", "Cutaneous photosensitivity", "Cutaneous syndactyly", "Cutaneous syndactyly of toes", "Cutis laxa", "Cutis marmorata", "Cyanosis", "Cyanotic episode", "Cyclopia", "Cystic hygroma", "Cystic liver disease", "Cystic renal dysplasia", "Cystinuria", "Cystoid macular edema", "Cytochrome c oxidase negative muscle fibers", "Dark urine", "Death in adolescence", "Death in adulthood", "Death in childhood", "Death in infancy", "Decerebrate rigidity", "Decreased absent ankle reflexes", "Decreased achilles reflex", "Decreased activity of mitochondrial complex i", "Decreased activity of mitochondrial complex ii", "Decreased activity of mitochondrial complex iii", "Decreased activity of mitochondrial complex iv", "Decreased activity of nadph oxidase", "Decreased activity of the pyruvate dehydrogenase complex", "Decreased adenosylcobalamin", "Decreased adipose tissue", "Decreased calvarial ossification", "Decreased cd4 cd8 ratio", "Decreased cervical spine flexion due to contractures of posterior cervical muscles", "Decreased cervical spine mobility", "Decreased circulating acth level", "Decreased circulating aldosterone level", "Decreased circulating androgen concentration", "Decreased circulating antibody level", "Decreased circulating copper concentration", "Decreased circulating cortisol level", "Decreased circulating follicle stimulating hormone concentration", "Decreased circulating gonadotropin concentration", "Decreased circulating iga level", "Decreased circulating igg level", "Decreased circulating igg subclass level", "Decreased circulating level of specific antibody", "Decreased circulating progesterone", "Decreased circulating total iga", "Decreased circulating total igg", "Decreased circulating total igm", "Decreased corneal reflex", "Decreased csf homovanillic acid", "Decreased facial expression", "Decreased fertility", "Decreased fertility in females", "Decreased fertility in males", "Decreased head circumference", "Decreased lacrimation", "Decreased ldl cholesterol concentration", "Decreased libido", "Decreased light and dark adapted electroretinogram amplitude", "Decreased lymphocyte apoptosis", "Decreased lymphocyte proliferation in response to mitogen", "Decreased mean corpuscular volume", "Decreased methylcobalamin", "Decreased methylmalonyl coa mutase activity", "Decreased muscle mass", "Decreased nasal nitric oxide", "Decreased number of large peripheral myelinated nerve fibers", "Decreased number of peripheral myelinated nerve fibers", "Decreased palmar creases", "Decreased patellar reflex", "Decreased plasma carnitine", "Decreased proportion of cd3 positive t cells", "Decreased proportion of cd4 positive helper t cells", "Decreased pulmonary function", "Decreased serum complement c3", "Decreased serum insulin like growth factor 1", "Decreased serum iron", "Decreased size of nerve terminals", "Decreased specific anti polysaccharide antibody level", "Decreased specific antibody response to protein vaccine", "Decreased specific antibody response to vaccination", "Decreased specific pneumococcal antibody level", "Decreased testicular size", "Decreased urine output", "Deep palmar crease", "Deep philtrum", "Deep plantar creases", "Deep set nails", "Deep venous thrombosis", "Deeply set eye", "Defective dna repair after ultraviolet radiation damage", "Defective t cell proliferation", "Deformed rib cage", "Deformed sella turcica", "Deformed tarsal bones", "Degeneration of the lateral corticospinal tracts", "Degeneration of the striatum", "Dehydration", "Delayed ability to roll over", "Delayed ability to sit", "Delayed ability to stand", "Delayed ability to walk", "Delayed closure of the anterior fontanelle", "Delayed cns myelination", "Delayed cranial suture closure", "Delayed epiphyseal ossification", "Delayed eruption of permanent teeth", "Delayed eruption of primary teeth", "Delayed eruption of teeth", "Delayed fine motor development", "Delayed gross motor development", "Delayed menarche", "Delayed myelination", "Delayed ossification of carpal bones", "Delayed puberty", "Delayed social development", "Delirium", "Delusions", "Dementia", "Demyelinating peripheral neuropathy", "Dental crowding", "Dental malocclusion", "Depletion of mitochondrial dna in muscle tissue", "Deposits immunoreactive to beta amyloid protein", "Depressed nasal bridge", "Depressed nasal ridge", "Depressed nasal tip", "Depression", "Dermal atrophy", "Dermal translucency", "Dermatological manifestations of systemic disorders", "Descending aortic dissection", "Desquamation of skin soon after birth", "Developmental cataract", "Developmental glaucoma", "Developmental regression", "Developmental stagnation", "Deviated nasal septum", "Deviation of the 2nd finger", "Deviation of the 3rd finger", "Deviation of the hallux", "Deviation of the hand or of fingers of the hand", "Deviation of the thumb", "Deviation of toes", "Diabetes insipidus", "Dialeptic seizure", "Diaphragmatic eventration", "Diaphragmatic paralysis", "Diaphragmatic weakness", "Diaphyseal sclerosis", "Diaphyseal thickening", "Diarrhea", "Diastasis recti", "Diastema", "Dicarboxylic aciduria", "Difficulty climbing stairs", "Difficulty in tongue movements", "Difficulty running", "Difficulty standing", "Difficulty walking", "Diffuse alveolar hemorrhage", "Diffuse cerebellar atrophy", "Diffuse cerebral atrophy", "Diffuse mesangial sclerosis", "Diffuse palmoplantar hyperkeratosis", "Diffuse white matter abnormalities", "Digenic inheritance", "Dilatation of the cerebral artery", "Dilatation of the ventricular cavity", "Dilated cardiomyopathy", "Dilated fourth ventricle", "Dilated third ventricle", "Dilation of lateral ventricles", "Dilation of virchow robin spaces", "Diminished ability to concentrate", "Diminished motivation", "Diminished movement", "Dimple chin", "Diplopia", "Disinhibition", "Displacement of the urethral meatus", "Disproportionate short limb short stature", "Disproportionate short stature", "Disproportionate short trunk short stature", "Disproportionate tall stature", "Disseminated intravascular coagulation", "Distal amyotrophy", "Distal arthrogryposis", "Distal joint laxity", "Distal lower limb amyotrophy", "Distal lower limb muscle weakness", "Distal muscle weakness", "Distal peripheral sensory neuropathy", "Distal sensory impairment", "Distal sensory impairment of all modalities", "Distal sensory loss of all modalities", "Distal upper limb amyotrophy", "Distal upper limb muscle weakness", "Disturbance of facial expression", "Dolichocephaly", "Double aortic arch", "Down sloping shoulders", "Downslanted palpebral fissures", "Downturned corners of mouth", "Drowsiness", "Drusen", "Dry hair", "Dry skin", "Duodenal adenocarcinoma", "Duodenal atresia", "Duodenal stenosis", "Duplicated collecting system", "Duplication involving bones of the feet", "Duplication of hand bones", "Duplication of the distal phalanx of hand", "Duplication of thumb phalanx", "Dysarthria", "Dyscalculia", "Dyschromatopsia", "Dysdiadochokinesis", "Dysesthesia", "Dysgammaglobulinemia", "Dysgenesis of the cerebellar vermis", "Dysgerminoma", "Dysgraphia", "Dyskinesia", "Dyslexia", "Dysmenorrhea", "Dysmetria", "Dysmetric saccades", "Dysostosis multiplex", "Dyspareunia", "Dysphagia", "Dysphasia", "Dysphonia", "Dysplasia of the femoral head", "Dysplastic corpus callosum", "Dyspnea", "Dystonia", "Dystrophic fingernails", "Dystrophic toenail", "Dysuria", "Ear pain", "Early onset absence seizures", "Early onset of sexual maturation", "Easy fatigability", "Ecchymosis", "Echolalia", "Eclabion", "Eclampsia", "Ectodermal dysplasia", "Ectopia lentis", "Ectopia pupillae", "Ectopic anus", "Ectopic calcification", "Ectopic kidney", "Ectrodactyly", "Ectropion", "Ectropion of lower eyelids", "Eczema", "Eczematoid dermatitis", "Edema of the dorsum of feet", "Edema of the dorsum of hands", "Eeg with abnormally slow frequencies", "Eeg with burst suppression", "Eeg with continuous slow activity", "Eeg with focal epileptiform discharges", "Eeg with focal sharp slow waves", "Eeg with focal sharp waves", "Eeg with focal spike waves", "Eeg with focal spikes", "Eeg with generalized sharp slow waves", "Eeg with generalized slow activity", "Eeg with irregular generalized spike and wave complexes", "Eeg with multifocal slow activity", "Eeg with polyspike wave complexes", "Eeg with spike wave complexes", "Elbow ankylosis", "Elbow flexion contracture", "Elevated alkaline phosphatase of bone origin", "Elevated calcitonin", "Elevated circulating alanine aminotransferase concentration", "Elevated circulating aspartate aminotransferase concentration", "Elevated circulating follicle stimulating hormone level", "Elevated circulating glutaric acid concentration", "Elevated circulating growth hormone concentration", "Elevated circulating long chain fatty acid concentration", "Elevated circulating parathyroid hormone level", "Elevated circulating thyroid stimulating hormone concentration", "Elevated creatine kinase after exercise", "Elevated diastolic blood pressure", "Elevated gamma glutamyltransferase level", "Elevated hemoglobin a1c", "Elevated hepatic transaminase", "Elevated lactate pyruvate ratio", "Elevated mean arterial pressure", "Elevated proportion of cd4 negative cd8 negative alpha beta regulatory t cells", "Elevated pulmonary artery pressure", "Elevated serum acid phosphatase", "Elevated systolic blood pressure", "Elevated tissue non specific alkaline phosphatase", "Elevated urinary carboxylic acid", "Elevated urinary delta aminolevulinic acid", "Elevated urinary dicarboxylic acid level", "Elevated urinary monocarboxylic acid level", "Elfin facies", "Elliptocytosis", "Elongated superior cerebellar peduncle", "Embryonal neoplasm", "Embryonal renal neoplasm", "Emg abnormality", "Emg axonal abnormality", "Emg chronic denervation signs", "Emg decremental response of compound muscle action potential to repetitive nerve stimulation", "Emg impaired neuromuscular transmission", "Emg myopathic abnormalities", "Emg myotonic discharges", "Emg neuropathic changes", "Emg slow motor conduction", "Emotional lability", "Emphysema", "Enamel hypoplasia", "Encephalocele", "Encephalopathy", "Enchondroma", "Endocardial fibroelastosis", "Endocardial fibrosis", "Endocarditis", "Enlarged cerebellum", "Enlarged cisterna magna", "Enlarged joints", "Enlarged kidney", "Enlarged metaphyses", "Enlarged ovaries", "Enlarged posterior fossa", "Enlarged thorax", "Enlarged tonsils", "Enlargement of the costochondral junction", "Enlargement of the wrists", "Enterocolitis", "Enthesitis", "Entropion", "Enuresis", "Ependymoma", "Epicanthus", "Epicanthus inversus", "Epidermal acanthosis", "Epidermal hyperkeratosis", "Epidermal nevus", "Epidermoid cyst", "Epigastric pain", "Epileptic encephalopathy", "Epileptic spasm", "Epiphora", "Epiphyseal dysplasia", "Epiphyseal stippling", "Epiretinal membrane", "Episodic ataxia", "Episodic hyperhidrosis", "Episodic hypertension", "Episodic pain", "Episodic respiratory distress", "Episodic tachypnea", "Episodic vomiting", "Epispadias", "Epistaxis", "Equinovarus deformity", "Equinus calcaneus", "Erectile dysfunction", "Erlenmeyer flask deformity of the femurs", "Eruption failure", "Erysipelas", "Erythema", "Erythema nodosum", "Erythematous papule", "Erythematous plaque", "Erythrocyte inclusion bodies", "Erythroderma", "Erythroid hyperplasia", "Erythroid hypoplasia", "Esodeviation", "Esophageal atresia", "Esophageal carcinoma", "Esophageal neoplasm", "Esophageal stenosis", "Esophageal stricture", "Esophageal varix", "Esophagitis", "Ethylmalonic aciduria", "Eunuchoid habitus", "Euryblepharon", "Eversion of lateral third of lower eyelids", "Everted upper lip vermilion", "Exaggerated cupid s bow", "Exaggerated startle response", "Exanthem", "Excessive daytime somnolence", "Excessive salivation", "Excessive wrinkled skin", "Excessive wrinkling of palmar skin", "Exercise induced muscle cramps", "Exercise induced muscle fatigue", "Exercise induced muscle stiffness", "Exercise induced myalgia", "Exercise induced myoglobinuria", "Exercise induced rhabdomyolysis", "Exercise intolerance", "Exertional dyspnea", "Exodeviation", "Exostoses", "Expressive aphasia", "Expressive language delay", "External ear malformation", "External genital hypoplasia", "External ophthalmoplegia", "Extra axial cerebrospinal fluid accumulation", "Extrahepatic cholestasis", "Extramedullary hematopoiesis", "Extrapyramidal dyskinesia", "Extrapyramidal muscular rigidity", "Exudative retinal detachment", "Eyelid coloboma", "Eyelid myoclonus", "Facial asymmetry", "Facial capillary hemangioma", "Facial cleft", "Facial diplegia", "Facial edema", "Facial erythema", "Facial grimacing", "Facial hemangioma", "Facial hyperostosis", "Facial hypertrichosis", "Facial hypotonia", "Facial myokymia", "Facial paralysis", "Facial shape deformation", "Facial telangiectasia", "Failure of eruption of permanent teeth", "Failure to thrive", "Failure to thrive in infancy", "Fair hair", "Falls", "Fasciculations", "Fasting hyperinsulinemia", "Fasting hypoglycemia", "Fat malabsorption", "Fatigable weakness of bulbar muscles", "Fatigable weakness of distal limb muscles", "Fatigable weakness of respiratory muscles", "Fatigable weakness of skeletal muscles", "Fatigable weakness of swallowing muscles", "Fatiguable weakness of proximal limb muscles", "Fatigue", "Fatty replacement of skeletal muscle", "Feeding difficulties", "Feeding difficulties in infancy", "Female external genitalia in individual with 46 xy karyotype", "Female hypogonadism", "Female infertility", "Female pseudohermaphroditism", "Female reproductive system neoplasm", "Female sexual dysfunction", "Femoral bowing", "Femoral hernia", "Fetal akinesia sequence", "Fetal distress", "Fetal onset", "Fetal polyuria", "Fetal ultrasound soft marker", "Fever", "Fibroadenoma of the breast", "Fibrosarcoma", "Fibrous tissue neoplasm", "Fibular aplasia", "Fibular hypoplasia", "Fine hair", "Finger agnosia", "Finger clinodactyly", "Finger swelling", "Finger syndactyly", "Fingernail dysplasia", "Fingerprint intracellular accumulation of autofluorescent lipopigment storage material", "First degree atrioventricular block", "First dorsal interossei muscle weakness", "Flank pain", "Flared iliac wing", "Flared metaphysis", "Flared nostrils", "Flaring of rib cage", "Flat acetabular roof", "Flat cornea", "Flat face", "Flat forehead", "Flat nasal alae", "Flat occiput", "Flattened epiphysis", "Flattened femoral epiphysis", "Flattened femoral head", "Flexion contracture of digit", "Flexion contracture of thumb", "Fluctuations in consciousness", "Flushing", "Foam cells", "Focal aware seizure", "Focal cortical dysplasia", "Focal cortical dysplasia type ii", "Focal dystonia", "Focal emotional seizure", "Focal impaired awareness seizure", "Focal motor seizure", "Focal motor status epilepticus", "Focal myoclonic seizure", "Focal non motor seizure", "Focal onset seizure", "Focal segmental glomerulosclerosis", "Focal t2 hyperintense basal ganglia lesion", "Focal t2 hyperintense brainstem lesion", "Focal tonic seizure", "Focal white matter lesions", "Follicular hyperkeratosis", "Follicular hyperplasia", "Follicular thyroid carcinoma", "Food allergy", "Food intolerance", "Foot acroosteolysis", "Foot dorsiflexor weakness", "Foot oligodactyly", "Fractures of the long bones", "Fragile nails", "Fragile skin", "Fragmented epiphyses", "Freckling", "Frequent falls", "Frontal balding", "Frontal cortical atrophy", "Frontal hirsutism", "Frontal lobe dementia", "Frontotemporal cerebral atrophy", "Frontotemporal dementia", "Full cheeks", "Fulminant hepatic failure", "Functional abnormality of male internal genitalia", "Functional abnormality of the gastrointestinal tract", "Functional abnormality of the inner ear", "Functional abnormality of the middle ear", "Functional intestinal obstruction", "Functional motor deficit", "Furrowed tongue", "Fused cervical vertebrae", "Fusion of the cerebellar hemispheres", "Gait ataxia", "Gait disturbance", "Gait imbalance", "Galactorrhea", "Gangrene", "Gastric ulcer", "Gastritis", "Gastroesophageal reflux", "Gastrointestinal atresia", "Gastrointestinal carcinoma", "Gastrointestinal hemorrhage", "Gastrointestinal infarctions", "Gastrointestinal inflammation", "Gastrointestinal obstruction", "Gastrointestinal stroma tumor", "Gastroparesis", "Gastrostomy tube feeding in infancy", "Gaze evoked nystagmus", "Generalized abnormality of skin", "Generalized aminoaciduria", "Generalized amyotrophy", "Generalized clonic seizure", "Generalized dystonia", "Generalized edema", "Generalized hirsutism", "Generalized hyperkeratosis", "Generalized hyperpigmentation", "Generalized hyperreflexia", "Generalized hypertrichosis", "Generalized hypopigmentation", "Generalized hypopigmentation of hair", "Generalized hypotonia", "Generalized joint laxity", "Generalized limb muscle atrophy", "Generalized lipodystrophy", "Generalized lymphadenopathy", "Generalized muscle weakness", "Generalized myoclonic atonic seizure", "Generalized myoclonic seizure", "Generalized neonatal hypotonia", "Generalized onset motor seizure", "Generalized onset seizure", "Generalized osteoporosis", "Generalized osteosclerosis", "Generalized tonic seizure", "Genetic anticipation", "Genital neoplasm", "Genu valgum", "Genu varum", "Germ cell neoplasia", "Germinoma", "Giant platelets", "Giant somatosensory evoked potentials", "Gingival bleeding", "Gingival fibromatosis", "Gingival overgrowth", "Gingival recession", "Gingivitis", "Glaucoma", "Glioblastoma multiforme", "Glioma", "Gliosis", "Global brain atrophy", "Glomerular deposits", "Glomerular sclerosis", "Glomerulonephritis", "Glomerulopathy", "Glomus jugular tumor", "Glossitis", "Glossoptosis", "Glucose intolerance", "Glutaric aciduria", "Glycosuria", "Goiter", "Gonadal dysgenesis", "Gonadal neoplasm", "Gonadoblastoma", "Gonosomal inheritance", "Gout", "Gowers sign", "Grammar specific speech disorder", "Granulocytopenia", "Granulomatosis", "Gray matter heterotopia", "Gynecomastia", "Hallucinations", "Hallux valgus", "Hamartoma", "Hamartoma of the eye", "Hamartoma of tongue", "Hamartomatous polyposis", "Hammertoe", "Hamstring contractures", "Hand apraxia", "Hand clenching", "Hand muscle weakness", "Hand oligodactyly", "Hand polydactyly", "Hand tremor", "Handgrip myotonia", "Happy demeanor", "Hashimoto thyroiditis", "Head banging", "Head titubation", "Head tremor", "Headache", "Heart block", "Heat intolerance", "Heinz bodies", "Hemangioblastoma", "Hemangiomatosis", "Hematemesis", "Hematological neoplasm", "Hemianopia", "Hemiatrophy", "Hemifacial spasm", "Hemihypertrophy", "Hemimegalencephaly", "Hemiparesis", "Hemiplegia hemiparesis", "Hemivertebrae", "Hemoglobinuria", "Hemolytic anemia", "Hemoptysis", "Hemorrhage of the eye", "Heparan sulfate excretion in urine", "Hepatic cysts", "Hepatic encephalopathy", "Hepatic failure", "Hepatic fibrosis", "Hepatic necrosis", "Hepatitis", "Hepatoblastoma", "Hepatocellular adenoma", "Hepatocellular carcinoma", "Hepatomegaly", "Hepatosplenomegaly", "Hereditary nonpolyposis colorectal carcinoma", "Hernia", "Herpes simplex encephalitis", "Heterochromia iridis", "Heterogeneous", "Heteronymous hemianopia", "Heterophoria", "Heterotaxy", "Heterotropia", "Hiatus hernia", "High anterior hairline", "High forehead", "High frequency hearing impairment", "High frequency sensorineural hearing impairment", "High hypermetropia", "High myopia", "High narrow palate", "High output congestive heart failure", "High palate", "High pitched voice", "Highly arched eyebrow", "Hip contracture", "Hip dislocation", "Hip dysplasia", "Hip flexor weakness", "Hip osteoarthritis", "Hip pain", "Hip subluxation", "Hirsutism", "Hoarse cry", "Hoarse voice", "Hodgkin lymphoma", "Holoprosencephaly", "Homocystinuria", "Honeycomb lung", "Horizontal eyebrow", "Horizontal nystagmus", "Horizontal pendular nystagmus", "Horseshoe kidney", "Humeroradial synostosis", "Hydranencephaly", "Hydrocele testis", "Hydrocephalus", "Hydrops fetalis", "Hydroureter", "Hydroxyprolinuria", "Hyperactive deep tendon reflexes", "Hyperactive patellar reflex", "Hyperactivity", "Hyperacusis", "Hyperaldosteronism", "Hyperammonemia", "Hyperautofluorescent retinal lesion", "Hypercalcemia", "Hyperchloremic acidosis", "Hypercholesterolemia", "Hypercoagulability", "Hyperconvex fingernails", "Hyperconvex nail", "Hyperesthesia", "Hyperextensibility at wrists", "Hyperextensibility of the finger joints", "Hyperextensible skin", "Hypergalactosemia", "Hyperglycemia", "Hypergonadotropic hypogonadism", "Hypergranulosis", "Hyperhidrosis", "Hyperhomocystinemia", "Hyperinsulinemic hypoglycemia", "Hyperintensity of cerebral white matter on mri", "Hyperkalemia", "Hyperkeratosis", "Hyperkeratotic papule", "Hyperketonemia", "Hyperkinetic movements", "Hyperlipidemia", "Hyperlipoproteinemia", "Hyperlordosis", "Hypermethioninemia", "Hypermetric saccades", "Hypermetropia", "Hypernatriuria", "Hyperorality", "Hyperostosis", "Hyperoxaluria", "Hyperparathyroidism", "Hyperphenylalaninemia", "Hyperphosphatemia", "Hyperphosphaturia", "Hyperpigmentation in sun exposed areas", "Hyperpigmentation of the skin", "Hyperpituitarism", "Hyperplasia of the maxilla", "Hyperreflexia", "Hyperreflexia in upper limbs", "Hypersomnia", "Hypersplenism", "Hypertelorism", "Hypertension associated with pheochromocytoma", "Hypertensive crisis", "Hyperthyroidism", "Hypertonia", "Hypertrichosis", "Hypertriglyceridemia", "Hypertrophic cardiomyopathy", "Hyperuricemia", "Hyperuricosuria", "Hyperventilation", "Hypoamylasemia", "Hypocalcemia", "Hypocalcemic seizures", "Hypocalcemic tetany", "Hypochloremia", "Hypocholesterolemia", "Hypochromia", "Hypochromic anemia", "Hypochromic microcytic anemia", "Hypodontia", "Hypoglycemic coma", "Hypoglycemic seizures", "Hypogonadism", "Hypogonadotropic hypogonadism", "Hypohidrosis", "Hypointensity of cerebral white matter on mri", "Hypokalemia", "Hypokalemic alkalosis", "Hypokalemic metabolic alkalosis", "Hypoketotic hypoglycemia", "Hypokinesia", "Hypolipidemia", "Hypolipoproteinemia", "Hypomelanotic macule", "Hypometric saccades", "Hypomimic face", "Hypoparathyroidism", "Hypophosphatemia", "Hypophosphatemic rickets", "Hypopigmentation of the fundus", "Hypopigmentation of the skin", "Hypopigmented macule", "Hypopigmented skin patches", "Hypopituitarism", "Hypoplasia of olfactory tract", "Hypoplasia of penis", "Hypoplasia of teeth", "Hypoplasia of the brainstem", "Hypoplasia of the corpus callosum", "Hypoplasia of the ear cartilage", "Hypoplasia of the epiglottis", "Hypoplasia of the femoral head", "Hypoplasia of the fovea", "Hypoplasia of the frontal lobes", "Hypoplasia of the iris", "Hypoplasia of the musculature", "Hypoplasia of the odontoid process", "Hypoplasia of the olfactory bulb", "Hypoplasia of the pons", "Hypoplasia of the radius", "Hypoplasia of the uterus", "Hypoplasia of the vagina", "Hypoplasia of the ventral pons", "Hypoplastic anemia", "Hypoplastic aortic arch", "Hypoplastic cervical vertebrae", "Hypoplastic dermoepidermal hemidesmosomes", "Hypoplastic facial bones", "Hypoplastic female external genitalia", "Hypoplastic fifth fingernail", "Hypoplastic fifth toenail", "Hypoplastic fingernail", "Hypoplastic frontal sinuses", "Hypoplastic heart", "Hypoplastic helices", "Hypoplastic hippocampus", "Hypoplastic ilia", "Hypoplastic iris stroma", "Hypoplastic labia majora", "Hypoplastic labia minora", "Hypoplastic nipples", "Hypoplastic pelvis", "Hypoplastic pubic rami", "Hypoplastic toenails", "Hypoplastic vertebral bodies", "Hypoproteinemia", "Hyporeflexia", "Hyporeflexia of lower limbs", "Hyporeflexia of upper limbs", "Hyposmia", "Hypotelorism", "Hypotension", "Hypothalamic gonadotropin releasing hormone deficiency", "Hypothalamic hamartoma", "Hypothalamic hypothyroidism", "Hypothermia", "Hypotriglyceridemia", "Hypouricemia", "Hypoventilation", "Hypovolemic shock", "Hypsarrhythmia", "Ichthyosis", "Ileus", "Imbalanced hemoglobin synthesis", "Immotile cilia", "Immotile sperm", "Immune dysregulation", "Immunodeficiency", "Immunologic hypersensitivity", "Impacted tooth", "Impaired adp induced platelet aggregation", "Impaired antigen specific response", "Impaired collagen induced platelet aggregation", "Impaired distal proprioception", "Impaired distal tactile sensation", "Impaired distal vibration sensation", "Impaired epinephrine induced platelet aggregation", "Impaired glucose tolerance", "Impaired horizontal smooth pursuit", "Impaired mastication", "Impaired neutrophil bactericidal activity", "Impaired pain sensation", "Impaired proprioception", "Impaired smooth pursuit", "Impaired social interactions", "Impaired t cell function", "Impaired tactile sensation", "Impaired tandem gait", "Impaired temperature sensation", "Impaired use of nonverbal behaviors", "Impaired vibration sensation at ankles", "Impaired vibration sensation in the lower limbs", "Impaired vibratory sensation", "Impaired visuospatial constructive cognition", "Impairment in personality functioning", "Impairment of activities of daily living", "Impotence", "Inability to walk", "Inappropriate antidiuretic hormone secretion", "Inappropriate behavior", "Inappropriate crying", "Inappropriate laughter", "Inappropriate sexual behavior", "Incisor macrodontia", "Incomitant strabismus", "Incomplete partition of the cochlea type ii", "Incomplete penetrance", "Incomprehensible speech", "Incoordination", "Increased adipose tissue", "Increased arm span", "Increased aspartate family amino acid level in urine", "Increased b cell count", "Increased blood pressure", "Increased blood urea nitrogen", "Increased body weight", "Increased bone mineral density", "Increased c peptide level", "Increased cerebral lipofuscin", "Increased circulating acth level", "Increased circulating androgen concentration", "Increased circulating antibody level", "Increased circulating cortisol level", "Increased circulating gonadotropin level", "Increased circulating iga level", "Increased circulating igg level", "Increased circulating igm level", "Increased circulating lactate dehydrogenase concentration", "Increased circulating prolactin concentration", "Increased circulating renin level", "Increased connective tissue", "Increased csf lactate", "Increased density of long bones", "Increased endomysial connective tissue", "Increased fecal porphyrin", "Increased female libido", "Increased head circumference", "Increased hepatic glycogen content", "Increased hepatocellular lipid droplets", "Increased intracranial pressure", "Increased intramyocellular lipid droplets", "Increased laxity of ankles", "Increased ldl cholesterol concentration", "Increased level of hippuric acid in urine", "Increased level of l fucose in urine", "Increased mean corpuscular hemoglobin concentration", "Increased mean corpuscular volume", "Increased megakaryocyte count", "Increased muscle fatiguability", "Increased muscle glycogen content", "Increased muscle lipid content", "Increased nuchal translucency", "Increased overbite", "Increased proteinogenic amino acid level in urine", "Increased sensitivity to ionizing radiation", "Increased serine family amino acid in urine", "Increased serum iron", "Increased serum lactate", "Increased serum pyruvate", "Increased serum serotonin", "Increased serum testosterone level", "Increased skull ossification", "Increased sulfur amino acid level in urine", "Increased susceptibility to fractures", "Increased theta frequency activity in eeg", "Increased total bilirubin", "Increased urinary cortisol level", "Increased urinary non proteinogenic amino acid level", "Increased urine alpha ketoglutarate concentration", "Increased urine proteinogenic amino acid derivative level", "Increased vertebral height", "Ineffective esophageal peristalsis", "Infantile axial hypotonia", "Infantile encephalopathy", "Infantile muscular hypotonia", "Infantile onset", "Infantile spasms", "Infection related seizure", "Infectious encephalitis", "Inferior lens subluxation", "Inferior vermis hypoplasia", "Infertility", "Inflammation of the large intestine", "Inflammatory abnormality of the eye", "Inflexible adherence to routines or rituals", "Inguinal freckling", "Inguinal hernia", "Insidious onset", "Insomnia", "Inspiratory stridor", "Insulin resistance", "Insulin resistant diabetes mellitus", "Intellectual disability borderline", "Intellectual disability mild", "Intellectual disability moderate", "Intellectual disability profound", "Intellectual disability progressive", "Intellectual disability severe", "Intercostal muscle weakness", "Interictal eeg abnormality", "Intermittent diarrhea", "Intermittent episodes of respiratory insufficiency due to muscle weakness", "Internally nucleated skeletal muscle fibers", "Interrupted aortic arch", "Interstitial cardiac fibrosis", "Interstitial pneumonitis", "Intestinal atresia", "Intestinal fistula", "Intestinal hypoplasia", "Intestinal malrotation", "Intestinal polyp", "Intestinal pseudo obstruction", "Intraalveolar phospholipid accumulation", "Intracellular accumulation of autofluorescent lipopigment storage material", "Intracranial hemorrhage", "Intracranial meningioma", "Intractable diarrhea", "Intrauterine growth retardation", "Intrinsic hand muscle atrophy", "Intussusception", "Inverted nipples", "Involuntary movements", "Iridocyclitis", "Iris atrophy", "Iris coloboma", "Iris hypopigmentation", "Iron accumulation in brain", "Iron accumulation in globus pallidus", "Iron deficiency anemia", "Irregular acetabular roof", "Irregular capital femoral epiphysis", "Irregular epiphyses", "Irregular femoral epiphysis", "Irregular hyperpigmentation", "Irregular menstruation", "Irregular vertebral endplates", "Irritability", "Ischemic stroke", "J shaped sella turcica", "Jaundice", "Jerky head movements", "Jerky ocular pursuit movements", "Joint contracture of the hand", "Joint contractures involving the joints of the feet", "Joint dislocation", "Joint hemorrhage", "Joint hyperflexibility", "Joint hypermobility", "Joint laxity", "Joint stiffness", "Joint subluxation", "Joint swelling", "Juvenile aseptic necrosis", "Juvenile cataract", "Juvenile myelomonocytic leukemia", "Juvenile onset", "Juvenile rheumatoid arthritis", "Keloids", "Keratitis", "Keratoconjunctivitis", "Keratosis pilaris", "Ketoacidosis", "Ketonuria", "Ketosis", "Ketotic hypoglycemia", "Kinetic tremor", "Knee clonus", "Knee dislocation", "Knee flexion contracture", "Kyphoscoliosis", "Kyphosis", "Labial hypertrophy", "Lack of insight", "Lack of peer relationships", "Lack of skin elasticity", "Lack of t cell function", "Lacrimal duct atresia", "Lacrimal duct stenosis", "Lacrimation abnormality", "Lactic acidosis", "Lacticaciduria", "Lactose intolerance", "Lagopthalmos", "Lambdoidal craniosynostosis", "Language impairment", "Large basal ganglia", "Large beaked nose", "Large earlobe", "Large face", "Large fleshy ears", "Large for gestational age", "Large foramen magnum", "Large forehead", "Large hands", "Large intestinal polyposis", "Large placenta", "Large sella turcica", "Laryngeal cleft", "Laryngeal dystonia", "Laryngeal hypoplasia", "Laryngeal stenosis", "Laryngeal stridor", "Laryngomalacia", "Laryngotracheomalacia", "Late onset", "Lateral clavicle hook", "Leber optic atrophy", "Left atrial enlargement", "Left ventricular hypertrophy", "Left ventricular noncompaction cardiomyopathy", "Left ventricular outflow tract obstruction", "Left ventricular systolic dysfunction", "Leg muscle stiffness", "Leiomyosarcoma", "Lens subluxation", "Lethal skeletal dysplasia", "Lethargy", "Leukemia", "Leukocytosis", "Leukodystrophy", "Leukoencephalopathy", "Leukonychia", "Leukopenia", "Lewy bodies", "Leydig cell neoplasia", "Lichenification", "Limb ataxia", "Limb dystonia", "Limb fasciculations", "Limb girdle muscle atrophy", "Limb girdle muscle weakness", "Limb girdle muscular dystrophy", "Limb hypertonia", "Limb joint contracture", "Limb muscle weakness", "Limb myoclonus", "Limb pain", "Limb tremor", "Limb undergrowth", "Limbal dermoid", "Limitation of joint mobility", "Limitation of knee mobility", "Limitation of movement at ankles", "Limitation of neck motion", "Limited elbow extension", "Limited elbow movement", "Limited extraocular movements", "Limited hip extension", "Limited hip movement", "Limited wrist extension", "Limited wrist movement", "Lingual dystonia", "Lipid accumulation in hepatocytes", "Lipoatrophy", "Lipodystrophy", "Lipoma", "Lissencephaly", "Liver abscess", "Lobulated tongue", "Localized hirsutism", "Localized osteoporosis", "Localized skin lesion", "Long clavicles", "Long ear", "Long eyelashes", "Long fingers", "Long foot", "Long hallux", "Long neck", "Long nose", "Long palm", "Long palpebral fissure", "Long penis", "Long philtrum", "Long thorax", "Long toe", "Long upper lip", "Lop ear", "Loss of ability to walk", "Loss of consciousness", "Loss of eyelashes", "Loss of purkinje cells in the cerebellar vermis", "Loss of speech", "Loss of subcutaneous adipose tissue in limbs", "Loss of voice", "Low alkaline phosphatase", "Low anterior hairline", "Low apgar score", "Low back pain", "Low frustration tolerance", "Low grade fever", "Low hanging columella", "Low levels of vitamin d", "Low molecular weight proteinuria", "Low plasma citrulline", "Low posterior hairline", "Low set nipples", "Low set posteriorly rotated ears", "Lower extremity joint dislocation", "Lower eyelid coloboma", "Lower limb amyotrophy", "Lower limb asymmetry", "Lower limb hyperreflexia", "Lower limb hypertonia", "Lower limb metaphyseal irregularity", "Lower limb muscle weakness", "Lower limb pain", "Lower limb spasticity", "Lower limb undergrowth", "Lumbar hyperlordosis", "Lumbar kyphosis", "Lumbar scoliosis", "Lung adenocarcinoma", "Lymphadenitis", "Lymphangiectasis", "Lymphangioma", "Lymphedema", "Lymphocytosis", "Lymphoma", "Lymphopenia", "Lymphoproliferative disorder", "Macrocephaly at birth", "Macrocytic anemia", "Macrodactyly", "Macrodontia", "Macrodontia of permanent maxillary central incisor", "Macroglossia", "Macrogyria", "Macroorchidism", "Macroscopic hematuria", "Macrotia", "Macrovesicular hepatic steatosis", "Macular atrophy", "Macular degeneration", "Macular hyperpigmentation", "Macular hypoplasia", "Macular purpura", "Macular thickening", "Macule", "Malabsorption", "Malar prominence", "Male hypogonadism", "Male infertility", "Male pseudohermaphroditism", "Male reproductive system neoplasm", "Male sexual dysfunction", "Malignant genitourinary tract tumor", "Malignant hyperthermia", "Malignant neoplasm of the central nervous system", "Malnutrition", "Malrotation of small bowel", "Mandibular aplasia", "Mandibular prognathia", "Mania", "Mask like facies", "Mastoiditis", "Maternal hypertension", "Maturity onset diabetes of the young", "Meconium stained amniotic fluid", "Medial flaring of the eyebrow", "Median cleft lip", "Median cleft palate", "Mediastinal lymphadenopathy", "Medullary nephrocalcinosis", "Medulloblastoma", "Megalencephaly", "Megaloblastic anemia", "Megalocornea", "Melanocytic nevus", "Melanoma", "Melena", "Membranoproliferative glomerulonephritis", "Memory impairment", "Meningioma", "Meningitis", "Meningocele", "Menorrhagia", "Mental deterioration", "Mesoaxial hand polydactyly", "Mesoaxial polydactyly", "Mesomelia", "Metabolic acidosis", "Metabolic alkalosis", "Metacarpophalangeal joint contracture", "Metamorphopsia", "Metaphyseal chondrodysplasia", "Metaphyseal cupping", "Metaphyseal dysplasia", "Metaphyseal irregularity", "Metaphyseal sclerosis", "Metaphyseal striations", "Metaphyseal widening", "Metatarsal synostosis", "Metatarsus adductus", "Metatarsus valgus", "Methemoglobinemia", "Methylmalonic acidemia", "Methylmalonic aciduria", "Metopic synostosis", "Metrorrhagia", "Microcornea", "Microcytic anemia", "Microdontia", "Microglossia", "Micrographia", "Micromelia", "Micronodular cirrhosis", "Micropenis", "Microphallus", "Microretrognathia", "Microscopic hematuria", "Microtia third degree", "Microvesicular hepatic steatosis", "Middle age onset", "Midface retrusion", "Midline defect of the nose", "Migraine", "Mild global developmental delay", "Mild hearing impairment", "Mild microcephaly", "Mild postnatal growth retardation", "Mild short stature", "Mildly elevated creatine kinase", "Milia", "Minicore myopathy", "Minimal change glomerulonephritis", "Misalignment of incisors", "Missing ribs", "Mitochondrial inheritance", "Mitochondrial myopathy", "Mitochondrial respiratory chain defects", "Mitral stenosis", "Mitral valve calcification", "Mitral valve prolapse", "Mitten deformity", "Mixed demyelinating and axonal polyneuropathy", "Mixed hearing impairment", "Mixed hypo and hyperpigmentation of the skin", "Moderate albuminuria", "Moderate global developmental delay", "Moderate sensorineural hearing impairment", "Moderately reduced visual acuity", "Molar tooth sign on mri", "Molluscoid pseudotumors", "Molluscum contagiosum", "Monocytosis", "Monotonic speech", "Mood swings", "Morning glory anomaly", "Morning myoclonic jerks", "Morphological abnormality of the corticospinal tract", "Morphological abnormality of the middle ear", "Morphological abnormality of the pyramidal tract", "Morphological abnormality of the vestibule of the inner ear", "Mortality aging", "Motor axonal neuropathy", "Motor delay", "Motor deterioration", "Motor neuron atrophy", "Motor polyneuropathy", "Motor regression", "Motor seizure", "Motor tics", "Mottled pigmentation", "Movement abnormality of the tongue", "Moyamoya phenomenon", "Mucosal telangiectasiae", "Multicystic kidney dysplasia", "Multifactorial inheritance", "Multifocal cerebral white matter abnormalities", "Multifocal epileptiform discharges", "Multifocal seizures", "Multiple cafe au lait spots", "Multiple enchondromatosis", "Multiple exostoses", "Multiple gastric polyps", "Multiple glomerular cysts", "Multiple impacted teeth", "Multiple joint contractures", "Multiple joint dislocation", "Multiple lentigines", "Multiple lipomas", "Multiple mitochondrial dna deletions", "Multiple myeloma", "Multiple prenatal fractures", "Multiple renal cysts", "Multiple rib fractures", "Multiple rows of eyelashes", "Multiple suture craniosynostosis", "Muscle abnormality related to mitochondrial dysfunction", "Muscle fiber atrophy", "Muscle fiber inclusion bodies", "Muscle fiber necrosis", "Muscle fiber splitting", "Muscle fiber tubular inclusions", "Muscle fibrillation", "Muscle flaccidity", "Muscle hypertrophy of the lower extremities", "Muscle spasm", "Muscle stiffness", "Muscle weakness", "Muscular dystrophy", "Muscular hypotonia of the trunk", "Muscular ventricular septal defect", "Mutism", "Myalgia", "Mydriasis", "Myelodysplasia", "Myelofibrosis", "Myeloid leukemia", "Myelomeningocele", "Myelopathy", "Myeloproliferative disorder", "Myocardial fibrosis", "Myoclonic seizure", "Myoclonic spasms", "Myoclonus", "Myofibrillar myopathy", "Myoglobinuria", "Myokymia", "Myopathic facies", "Myopathy", "Myopia", "Myositis", "Myotonia", "Naevus flammeus of the eyelid", "Nail dysplasia", "Nail dystrophy", "Nail pits", "Narrow face", "Narrow foot", "Narrow forehead", "Narrow iliac wing", "Narrow internal auditory canal", "Narrow jaw", "Narrow mouth", "Narrow nasal bridge", "Narrow nasal ridge", "Narrow nose", "Narrow palate", "Narrow palm", "Narrow palpebral fissure", "Narrow pelvis bone", "Narrow vertebral interpedicular distance", "Nasal congestion", "Nasal regurgitation", "Nasal speech", "Nasogastric tube feeding", "Nasogastric tube feeding in infancy", "Nasolacrimal duct obstruction", "Natal tooth", "Nausea", "Nausea and vomiting", "Neck flexor weakness", "Neck muscle weakness", "Negativism", "Nemaline bodies", "Neonatal alloimmune thrombocytopenia", "Neonatal asphyxia", "Neonatal breathing dysregulation", "Neonatal death", "Neonatal hyperbilirubinemia", "Neonatal hypoglycemia", "Neonatal hypotonia", "Neonatal insulin dependent diabetes mellitus", "Neonatal onset", "Neonatal respiratory distress", "Neoplasm", "Neoplasm by histology", "Neoplasm of fatty tissue", "Neoplasm of head and neck", "Neoplasm of striated muscle", "Neoplasm of the adrenal cortex", "Neoplasm of the adrenal gland", "Neoplasm of the breast", "Neoplasm of the colon", "Neoplasm of the ear", "Neoplasm of the endocrine system", "Neoplasm of the eye", "Neoplasm of the gallbladder", "Neoplasm of the gastrointestinal tract", "Neoplasm of the genitourinary tract", "Neoplasm of the heart", "Neoplasm of the inner ear", "Neoplasm of the large intestine", "Neoplasm of the larynx", "Neoplasm of the liver", "Neoplasm of the male external genitalia", "Neoplasm of the nervous system", "Neoplasm of the oral cavity", "Neoplasm of the pancreas", "Neoplasm of the parathyroid gland", "Neoplasm of the peripheral nervous system", "Neoplasm of the pituitary gland", "Neoplasm of the rectum", "Neoplasm of the respiratory system", "Neoplasm of the skeletal system", "Neoplasm of the skin", "Neoplasm of the small intestine", "Neoplasm of the stomach", "Neoplasm of the thymus", "Neoplasm of the thyroid gland", "Neoplasm of the tongue", "Neoplasm of the tracheobronchial system", "Nephritis", "Nephrocalcinosis", "Nephrolithiasis", "Nephronophthisis", "Nephropathy", "Nephrotic syndrome", "Neuralgia", "Neurodegeneration", "Neuroendocrine neoplasm", "Neurofibrillary tangles", "Neurofibromas", "Neurogenic bladder", "Neuroinflammation", "Neuromuscular dysphagia", "Neuronal loss in basal ganglia", "Neuronal loss in central nervous system", "Neuronal loss in the cerebral cortex", "Neuropathic arthropathy", "Neutropenia in presence of anti neutropil antibodies", "Neutrophilia", "Nevus", "Night sweats", "No social interaction", "Nocturia", "Nocturnal hypoventilation", "Nocturnal seizures", "Nodular goiter", "Non hodgkin lymphoma", "Non midline cleft lip", "Non midline cleft palate", "Non motor seizure", "Non obstructive azoospermia", "Noncommunicating hydrocephalus", "Noncompaction cardiomyopathy", "Nonimmune hydrops fetalis", "Nonketotic hypoglycemia", "Nonprogressive", "Nonprogressive cerebellar ataxia", "Nonprogressive encephalopathy", "Nonspherocytic hemolytic anemia", "Normochromic anemia", "Normocytic anemia", "Nuclear cataract", "Numerous nevi", "Numerous pigmented freckles", "Nyctalopia", "Nystagmus induced head nodding", "Obsessive compulsive behavior", "Obsessive compulsive trait", "Obstructive sleep apnea", "Occipital encephalocele", "Occipital meningocele", "Ocular albinism", "Ocular anterior segment dysgenesis", "Ocular pain", "Oculogyric crisis", "Oculomotor apraxia", "Oculomotor nerve palsy", "Odontogenic neoplasm", "Oligoarthritis", "Oligodactyly", "Oligodontia", "Oligohydramnios", "Oligomenorrhea", "Oligosacchariduria", "Oligospermia", "Oliguria", "Olivopontocerebellar atrophy", "Olivopontocerebellar hypoplasia", "Omphalocele", "Onion bulb formation", "Onset", "Onychogryposis", "Onychogryposis of toenails", "Onycholysis", "Open angle glaucoma", "Open bite", "Open mouth", "Open operculum", "Ophthalmoparesis", "Opisthotonus", "Opportunistic infection", "Opsoclonus", "Optic atrophy", "Optic disc coloboma", "Optic disc hypoplasia", "Optic disc pallor", "Optic nerve compression", "Optic nerve dysplasia", "Optic nerve hypoplasia", "Optic neuropathy", "Oral aversion", "Oral cavity bleeding", "Oral cleft", "Oral leukoplakia", "Oral mucosal blisters", "Oral pharyngeal dysphagia", "Oral ulcer", "Orchitis", "Organic aciduria", "Orofacial dyskinesia", "Oromandibular dystonia", "Oromotor apraxia", "Oroticaciduria", "Orthopnea", "Orthostatic hypotension", "Orthostatic hypotension due to autonomic dysfunction", "Osteoarthritis", "Osteochondroma", "Osteochondrosis", "Osteolysis", "Osteolysis involving bones of the feet", "Osteolysis involving bones of the upper limbs", "Osteolytic defects of the distal phalanges of the hand", "Osteomalacia", "Osteomyelitis", "Osteopenia", "Osteopetrosis", "Osteoporosis", "Osteosarcoma", "Otitis media", "Otosclerosis", "Oval face", "Ovarian carcinoma", "Ovarian cyst", "Ovarian gonadoblastoma", "Ovarian neoplasm", "Ovarian papillary adenocarcinoma", "Overfolding of the superior helices", "Overfriendliness", "Overgrowth", "Overhanging nasal tip", "Overlapping fingers", "Overlapping toe", "Overriding aorta", "Overtubulated long bones", "Overweight", "Ovoid vertebral bodies", "Ovotestis", "Pace of progression", "Pain", "Pain in head and neck region", "Pain insensitivity", "Painless fractures due to injury", "Pallor", "Palmar hyperhidrosis", "Palmar pits", "Palmar telangiectasia", "Palmoplantar blistering", "Palmoplantar cutis laxa", "Palmoplantar hyperhidrosis", "Palpebral edema", "Palpitations", "Pancreatic adenocarcinoma", "Pancreatic cysts", "Pancreatic endocrine tumor", "Pancreatic fibrosis", "Pancreatic hypoplasia", "Pancreatic islet cell hyperplasia", "Pancreatitis", "Pancytopenia", "Panhypogammaglobulinemia", "Panhypopituitarism", "Panniculitis", "Papillary renal cell carcinoma", "Papillary thyroid carcinoma", "Papilledema", "Papilloma", "Papule", "Paracentral scotoma", "Paraganglioma", "Parakeratosis", "Paralysis", "Paranoia", "Paraparesis", "Paraplegia", "Paraplegia paraparesis", "Parasomnia", "Parathyroid adenoma", "Parathyroid carcinoma", "Parathyroid hyperplasia", "Paresthesia", "Parietal bossing", "Parietal cortical atrophy", "Parietal foramina", "Parkinsonism", "Parkinsonism with favorable response to dopaminergic medication", "Paronychia", "Paroxysmal bursts of laughter", "Paroxysmal dystonia", "Paroxysmal involuntary eye movements", "Paroxysmal ventricular tachycardia", "Partial absence of thumb", "Partial agenesis of the corpus callosum", "Partial albinism", "Partial anomalous pulmonary venous return", "Partial duplication of the phalanx of hand", "Patchy alopecia", "Patchy changes of bone mineral density", "Patchy hypopigmentation of hair", "Patchy palmoplantar hyperkeratosis", "Patellar aplasia", "Patellar dislocation", "Patellar hypoplasia", "Patellar subluxation", "Patent ductus arteriosus", "Patent foramen ovale", "Pathologic fracture", "Pectus carinatum", "Pectus excavatum", "Pectus excavatum of inferior sternum", "Pedal edema", "Pediatric onset", "Pelvic girdle muscle weakness", "Pelvic kidney", "Pendular nystagmus", "Penetrating foot ulcers", "Peptic ulcer", "Percussion myotonia", "Periauricular skin pits", "Pericardial effusion", "Pericarditis", "Perifoveal ring of hyperautofluorescence", "Perimembranous ventricular septal defect", "Perineal fistula", "Periodic paralysis", "Periodontitis", "Periorbital edema", "Periorbital fullness", "Peripheral arterial stenosis", "Peripheral arteriovenous fistula", "Peripheral axonal degeneration", "Peripheral axonal neuropathy", "Peripheral cyanosis", "Peripheral demyelination", "Peripheral edema", "Peripheral hypermyelination", "Peripheral hypomyelination", "Peripheral neuropathy", "Peripheral opacification of the cornea", "Peripheral pulmonary artery stenosis", "Peripheral retinal avascularization", "Peripheral visual field loss", "Periportal fibrosis", "Perisylvian polymicrogyria", "Peritoneal abscess", "Peritonitis", "Periventricular cysts", "Periventricular heterotopia", "Periventricular leukomalacia", "Periventricular nodular heterotopia", "Periventricular white matter hyperintensities", "Peroneal muscle atrophy", "Perseveration", "Persistence of hemoglobin f", "Persistence of primary teeth", "Persistent ebv viremia", "Persistent head lag", "Personality changes", "Personality disorder", "Pes cavus", "Pes planus", "Pes valgus", "Petechiae", "Peters anomaly", "Pharyngitis", "Phenotypic variability", "Pheochromocytoma", "Phimosis", "Phocomelia", "Phonophobia", "Photophobia", "Photopsia", "Photoreceptor layer loss on macular oct", "Phthisis bulbi", "Physical urticaria", "Pierre robin sequence", "Pigmentary retinopathy", "Pili canaliculi", "Pili torti", "Pilomatrixoma", "Pineal cyst", "Pituitary adenoma", "Pituitary growth hormone cell adenoma", "Pituitary hypothyroidism", "Pituitary prolactin cell adenoma", "Plagiocephaly", "Plantar hyperkeratosis", "Platybasia", "Platyspondyly", "Pleural effusion", "Pleuritis", "Pneumonia", "Pneumothorax", "Poikilocytosis", "Poikiloderma", "Pointed chin", "Polar cataract", "Pollakisuria", "Polyarticular arthropathy", "Polyclonal elevation of igm", "Polycystic kidney dysplasia", "Polycystic liver disease", "Polycythemia", "Polydactyly", "Polygenic inheritance", "Polyhydramnios", "Polymicrogyria", "Polyneuropathy", "Polyphagia", "Polysplenia", "Polyuria", "Pontocerebellar atrophy", "Poor appetite", "Poor coordination", "Poor eye contact", "Poor fine motor coordination", "Poor gross motor coordination", "Poor head control", "Poor motor coordination", "Poor speech", "Poor suck", "Poor wound healing", "Popliteal pterygium", "Porencephalic cyst", "Porokeratosis", "Porphyrinuria", "Portal fibrosis", "Portal vein thrombosis", "Positional foot deformity", "Positive romberg sign", "Post partum hemorrhage", "Postaxial foot polydactyly", "Postaxial hand polydactyly", "Postaxial polydactyly", "Posterior blepharitis", "Posterior embryotoxon", "Posterior fossa cyst", "Posterior pharyngeal cleft", "Posterior pituitary dysgenesis", "Posterior polar cataract", "Posterior subcapsular cataract", "Posterior uveitis", "Posteriorly rotated ears", "Postexertional malaise", "Postnatal growth retardation", "Postural instability", "Postural tremor", "Potter facies", "Preauricular skin tag", "Preaxial foot polydactyly", "Preaxial hand polydactyly", "Preaxial polydactyly", "Precocious atherosclerosis", "Predominantly lower limb lymphedema", "Prelingual sensorineural hearing impairment", "Premature adrenarche", "Premature arteriosclerosis", "Premature birth", "Premature coronary artery atherosclerosis", "Premature graying of hair", "Premature loss of primary teeth", "Premature loss of teeth", "Premature osteoarthritis", "Premature ovarian insufficiency", "Premature pubarche", "Premature rupture of membranes", "Premature skin wrinkling", "Premature thelarche", "Premature ventricular contraction", "Prematurely aged appearance", "Prenatal maternal abnormality", "Prenatal movement abnormality", "Primary adrenal insufficiency", "Primary amenorrhea", "Primary congenital glaucoma", "Primary gonadal insufficiency", "Primary hypercortisolism", "Primary hyperparathyroidism", "Primary microcephaly", "Primary peritoneal carcinoma", "Primitive neuroectodermal tumor", "Primitive reflex", "Productive cough", "Profound global developmental delay", "Profound hearing impairment", "Profound sensorineural hearing impairment", "Progeroid facial appearance", "Progressive", "Progressive cerebellar ataxia", "Progressive distal muscle weakness", "Progressive encephalopathy", "Progressive external ophthalmoplegia", "Progressive extrapyramidal movement disorder", "Progressive flexion contractures", "Progressive gait ataxia", "Progressive hearing impairment", "Progressive inability to walk", "Progressive leukoencephalopathy", "Progressive macrocephaly", "Progressive microcephaly", "Progressive muscle weakness", "Progressive neurologic deterioration", "Progressive night blindness", "Progressive peripheral neuropathy", "Progressive pes cavus", "Progressive proximal muscle weakness", "Progressive psychomotor deterioration", "Progressive pulmonary function impairment", "Progressive sensorineural hearing impairment", "Progressive spastic paraparesis", "Progressive spastic paraplegia", "Progressive spastic quadriplegia", "Progressive spasticity", "Progressive visual field defects", "Progressive visual loss", "Prolinuria", "Prolonged bleeding after dental extraction", "Prolonged bleeding after surgery", "Prolonged bleeding following circumcision", "Prolonged bleeding following procedure", "Prolonged bleeding time", "Prolonged neonatal jaundice", "Prolonged partial thromboplastin time", "Prolonged qtc interval", "Prominent antihelix", "Prominent antitragus", "Prominent digit pad", "Prominent ear helix", "Prominent eyelashes", "Prominent forehead", "Prominent metopic ridge", "Prominent nasal bridge", "Prominent nasal tip", "Prominent nasolabial fold", "Prominent nose", "Prominent occiput", "Prominent sternum", "Prominent superficial blood vessels", "Prominent supraorbital ridges", "Prominent umbilicus", "Prominent veins on trunk", "Proportionate short stature", "Proportionate tall stature", "Proptosis", "Prostate neoplasm", "Protein avoidance", "Protein losing enteropathy", "Protracted diarrhea", "Protruding ear", "Protruding tongue", "Protrusio acetabuli", "Protuberant abdomen", "Proximal amyotrophy", "Proximal femoral epiphysiolysis", "Proximal femoral metaphyseal abnormality", "Proximal femoral metaphyseal irregularity", "Proximal muscle weakness", "Proximal muscle weakness in lower limbs", "Proximal muscle weakness in upper limbs", "Proximal renal tubular acidosis", "Proximal symphalangism", "Proximal tubulopathy", "Proximal upper limb amyotrophy", "Pruritus", "Pseudoarthrosis", "Pseudobulbar paralysis", "Pseudobulbar signs", "Pseudoepiphyses", "Pseudoepiphyses of hand bones", "Pseudoepiphyses of the metacarpals", "Pseudohypoaldosteronism", "Pseudohypoparathyroidism", "Psoriasiform dermatitis", "Psychogenic non epileptic seizure", "Psychomotor deterioration", "Psychomotor retardation", "Psychosis", "Psychotic episodes", "Psychotic mentation", "Pterygium", "Ptosis", "Puberty and gonadal disorders", "Pulmonary artery atresia", "Pulmonary artery dilatation", "Pulmonary artery hypoplasia", "Pulmonary artery stenosis", "Pulmonary carcinoid tumor", "Pulmonary cyst", "Pulmonary edema", "Pulmonary embolism", "Pulmonary fibrosis", "Pulmonary hemorrhage", "Pulmonary hypoplasia", "Pulmonary infiltrates", "Pulmonary insufficiency", "Pulmonary interstitial high resolution computed tomography abnormality", "Pulmonary venous hypertension", "Pulmonic stenosis", "Pulverulent cataract", "Punctate cataract", "Pure red cell aplasia", "Purpura", "Pustule", "Pyelonephritis", "Pyoderma gangrenosum", "Pyridoxine responsive sideroblastic anemia", "Quadriceps muscle weakness", "Radial bowing", "Radial deviation of the 2nd finger", "Radial deviation of the hand", "Radial deviation of the hand or of fingers of the hand", "Radioulnar dislocation", "Radioulnar synostosis", "Ragged red muscle fibers", "Rapidly progressive", "Raynaud phenomenon", "Reactive hypoglycemia", "Receptive language delay", "Rectal fistula", "Rectal prolapse", "Recurrent", "Recurrent abscess formation", "Recurrent acute respiratory tract infection", "Recurrent aspergillus infections", "Recurrent aspiration pneumonia", "Recurrent bacterial infections", "Recurrent bacterial skin infections", "Recurrent bronchitis", "Recurrent bronchopulmonary infections", "Recurrent corneal erosions", "Recurrent cutaneous abscess formation", "Recurrent ear infections", "Recurrent fever", "Recurrent fractures", "Recurrent gastroenteritis", "Recurrent hand flapping", "Recurrent herpes", "Recurrent hypoglycemia", "Recurrent infection of the gastrointestinal tract", "Recurrent joint dislocation", "Recurrent lower respiratory tract infections", "Recurrent mycobacterial infections", "Recurrent opportunistic infections", "Recurrent otitis media", "Recurrent pancreatitis", "Recurrent paroxysmal headache", "Recurrent pharyngitis", "Recurrent pneumonia", "Recurrent respiratory infections", "Recurrent sinopulmonary infections", "Recurrent sinusitis", "Recurrent skin infections", "Recurrent staphylococcal infections", "Recurrent staphylococcus aureus infections", "Recurrent upper and lower respiratory tract infections", "Recurrent urinary tract infections", "Recurrent viral infections", "Red eye", "Red green dyschromatopsia", "Red hair", "Reduced antigen specific t cell proliferation", "Reduced antithrombin iii activity", "Reduced brain n acetyl aspartate level by mrs", "Reduced c peptide level", "Reduced circulating prolactin concentration", "Reduced consciousness confusion", "Reduced delayed hypersensitivity", "Reduced factor viii activity", "Reduced factor xi activity", "Reduced factor xii activity", "Reduced factor xiii activity", "Reduced forced expiratory volume in one second", "Reduced forced vital capacity", "Reduced natural killer cell count", "Reduced pancreatic beta cells", "Reduced protein c activity", "Reduced protein s activity", "Reduced renal corticomedullary differentiation", "Reduced sperm motility", "Reduced subcutaneous adipose tissue", "Reduced systolic function", "Reduced tendon reflexes", "Reduced visual acuity", "Reduced vital capacity", "Reduction of neutrophil motility", "Redundant neck skin", "Redundant skin", "Refractory anemia", "Regional abnormality of skin", "Relative macrocephaly", "Renal agenesis", "Renal angiomyolipoma", "Renal cell carcinoma", "Renal cortical cysts", "Renal cortical microcysts", "Renal corticomedullary cysts", "Renal cyst", "Renal duplication", "Renal dysplasia", "Renal fanconi syndrome", "Renal fibrosis", "Renal hamartoma", "Renal hypoplasia", "Renal hypoplasia aplasia", "Renal insufficiency", "Renal magnesium wasting", "Renal malrotation", "Renal phosphate wasting", "Renal potassium wasting", "Renal salt wasting", "Renal steatosis", "Renal tubular acidosis", "Renal tubular atrophy", "Renal tubular dysfunction", "Renal tubular epithelial necrosis", "Renovascular hypertension", "Repetitive compulsive behavior", "Respiratory alkalosis", "Respiratory arrest", "Respiratory distress", "Respiratory failure", "Respiratory failure requiring assisted ventilation", "Respiratory insufficiency", "Respiratory insufficiency due to defective ciliary clearance", "Respiratory paralysis", "Respiratory tract infection", "Response to drugs acting on neuromuscular transmission", "Resting tremor", "Restless legs", "Restlessness", "Restrictive behavior", "Restrictive cardiomyopathy", "Restrictive ventilatory defect", "Reticular hyperpigmentation", "Reticulated skin pigmentation", "Reticulocytopenia", "Reticulocytosis", "Retinal arterial tortuosity", "Retinal arteriolar tortuosity", "Retinal atrophy", "Retinal coloboma", "Retinal degeneration", "Retinal detachment", "Retinal dysplasia", "Retinal dystrophy", "Retinal fold", "Retinal hamartoma", "Retinal hemorrhage", "Retinal neovascularization", "Retinal nonattachment", "Retinal perforation", "Retinal pigment epithelial atrophy", "Retinal pigment epithelial mottling", "Retinal telangiectasia", "Retinal thinning", "Retinal vascular tortuosity", "Retinopathy", "Retrocollis", "Retrognathia", "Rhabdomyolysis", "Rhabdomyosarcoma", "Rhegmatogenous retinal detachment", "Rheumatoid arthritis", "Rheumatoid factor positive", "Rhinitis", "Rhizomelia", "Rib fusion", "Rib segmentation abnormalities", "Rickets", "Ridged nail", "Rieger anomaly", "Right aortic arch with mirror image branching", "Right bundle branch block", "Right ventricular cardiomyopathy", "Right ventricular dilatation", "Right ventricular hypertrophy", "Rigidity", "Rimmed vacuoles", "Rod cone dystrophy", "Rotary nystagmus", "Round ear", "Round face", "Saccadic oscillation", "Saccadic smooth pursuit", "Sagittal craniosynostosis", "Sandal gap", "Sarcoma", "Scaling skin", "Scanning speech", "Scaphocephaly", "Scapular winging", "Scarring", "Scarring alopecia of scalp", "Schistocytosis", "Schizencephaly", "Schizophrenia", "Schwannoma", "Scleral staphyloma", "Sclerocornea", "Scleroderma", "Sclerosis of hand bone", "Sclerosis of skull base", "Sclerotic vertebral endplates", "Scotoma", "Scrotal hypoplasia", "Sea blue histiocytosis", "Seborrheic dermatitis", "Second degree atrioventricular block", "Secondary amenorrhea", "Secondary growth hormone deficiency", "Secondary microcephaly", "Secretory diarrhea", "Secundum atrial septal defect", "Segmental peripheral demyelination remyelination", "Selective tooth agenesis", "Self injurious behavior", "Self mutilation", "Semilobar holoprosencephaly", "Senile plaques", "Sensorimotor neuropathy", "Sensory ataxia", "Sensory axonal neuropathy", "Sensory neuropathy", "Sepsis", "Septic arthritis", "Septo optic dysplasia", "Serositis", "Severe b lymphocytopenia", "Severe combined immunodeficiency", "Severe cytomegalovirus infection", "Severe demyelination of the white matter", "Severe expressive language delay", "Severe failure to thrive", "Severe global developmental delay", "Severe hearing impairment", "Severe infection", "Severe intrauterine growth retardation", "Severe lactic acidosis", "Severe muscular hypotonia", "Severe photosensitivity", "Severe postnatal growth retardation", "Severe short limb dwarfism", "Severe short stature", "Severe varicella zoster infection", "Severe viral infection", "Severely reduced visual acuity", "Shagreen patch", "Shallow acetabular fossae", "Shallow anterior chamber", "Shallow orbits", "Shawl scrotum", "Shield chest", "Shock", "Short 1st metacarpal", "Short attention span", "Short chin", "Short clavicles", "Short columella", "Short digit", "Short face", "Short femur", "Short foot", "Short fourth metatarsal", "Short lingual frenulum", "Short long bone", "Short lower limbs", "Short middle phalanx of finger", "Short nail", "Short nose", "Short palm", "Short palpebral fissure", "Short phalanx of the thumb", "Short philtrum", "Short proximal phalanx of finger", "Short ribs", "Short stepped shuffling gait", "Short sternum", "Short thorax", "Short thumb", "Short tibia", "Short umbilical cord", "Short upper lip", "Shortened pr interval", "Shortened qt interval", "Shortening of all distal phalanges of the fingers", "Shortening of all middle phalanges of the fingers", "Shortening of all phalanges of the toes", "Shoulder dislocation", "Shoulder girdle muscle atrophy", "Shoulder girdle muscle weakness", "Shuffling gait", "Shyness", "Sideroblastic anemia", "Simple ear", "Simple febrile seizure", "Simplified gyral pattern", "Single fiber emg abnormality", "Single naris", "Single transverse palmar crease", "Single ventricle", "Sinus bradycardia", "Sinus tachycardia", "Sirenomelia", "Skeletal dysplasia", "Skeletal muscle atrophy", "Skeletal muscle hypertrophy", "Skeletal myopathy", "Skin appendage neoplasm", "Skin dimple", "Skin erosion", "Skin nodule", "Skin picking", "Skin pit", "Skin plaque", "Skin rash", "Skin tags", "Skin ulcer", "Skin vesicle", "Skull asymmetry", "Slanting of the palpebral fissure", "Sleep apnea", "Sleep disturbance", "Sleep wake cycle disturbance", "Slender build", "Slender finger", "Slender long bone", "Slender toe", "Sloping forehead", "Slow decrease in visual acuity", "Slow pupillary light response", "Slow saccadic eye movements", "Slowly progressive", "Slurred speech", "Small anterior fontanelle", "Small basal ganglia", "Small cerebral cortex", "Small earlobe", "Small epiphyses", "Small face", "Small for gestational age", "Small hand", "Small intestinal dysmotility", "Small nail", "Small placenta", "Smooth muscle antibody positivity", "Smooth philtrum", "Snoring", "Social and occupational deterioration", "Soft doughy skin", "Soft skin", "Soft tissue sarcoma", "Solitary median maxillary central incisor", "Somatic mosaicism", "Somatic mutation", "Somatic sensory dysfunction", "Sound sensitivity", "Sparse and thin eyebrow", "Sparse body hair", "Sparse eyebrow", "Sparse eyelashes", "Sparse hair", "Sparse lateral eyebrow", "Sparse or absent eyelashes", "Sparse scalp hair", "Spastic ataxia", "Spastic diplegia", "Spastic dysarthria", "Spastic gait", "Spastic hyperactive bladder", "Spastic paraparesis", "Spastic paraparetic gait", "Spastic paraplegia", "Spastic tetraparesis", "Spastic tetraplegia", "Spasticity", "Specific learning disability", "Speech apraxia", "Speech articulation difficulties", "Spider hemangioma", "Spina bifida", "Spina bifida occulta", "Spinal canal stenosis", "Spinal cord compression", "Spinal cord lesion", "Spinal cord tumor", "Spinal deformities", "Spinal muscular atrophy", "Spinal rigidity", "Splanchnic vein thrombosis", "Splenomegaly", "Split nail", "Spoken word recognition deficit", "Spondyloepimetaphyseal dysplasia", "Spondyloepiphyseal dysplasia", "Spondylolisthesis", "Spondylolysis", "Spontaneous abortion", "Spontaneous hemolytic crises", "Spontaneous pneumothorax", "Spontaneous recurrent epistaxis", "Sporadic", "Spotty hyperpigmentation", "Spotty hypopigmentation", "Sprengel anomaly", "Squamous cell carcinoma", "Squamous cell carcinoma of the skin", "Square face", "Squared iliac bones", "St segment elevation", "Stage 5 chronic kidney disease", "Staring gaze", "Status epilepticus", "Status epilepticus with prominent motor symptoms", "Stenosis of the external auditory canal", "Steppage gait", "Stereotypical hand wringing", "Stereotypy", "Steroid resistant nephrotic syndrome", "Stiff skin", "Stillbirth", "Stomach cancer", "Stomatitis", "Stomatocytosis", "Stooped posture", "Streak ovary", "Striae distensae", "Stridor", "Stroke", "Stroke like episode", "Stuttering", "Subacute progressive viral hepatitis", "Subarachnoid hemorrhage", "Subcapsular cataract", "Subcortical band heterotopia", "Subcortical cerebral atrophy", "Subcortical heterotopia", "Subcutaneous hemorrhage", "Subcutaneous lipoma", "Subcutaneous nodule", "Subdural hemorrhage", "Subependymal cysts", "Subglottic stenosis", "Submucous cleft of soft and hard palate", "Submucous cleft soft palate", "Subretinal fluid", "Subsarcolemmal accumulations of abnormally shaped mitochondria", "Substantia nigra gliosis", "Subvalvular aortic stenosis", "Sudden death", "Sudden episodic apnea", "Sudden loss of visual acuity", "Suicidal ideation", "Sunken cheeks", "Supernumerary bones of the axial skeleton", "Supernumerary nipple", "Supernumerary spleens", "Supernumerary tooth", "Supranuclear gaze palsy", "Supranuclear ophthalmoplegia", "Supravalvular aortic stenosis", "Supraventricular arrhythmia", "Supraventricular tachycardia", "Swan neck like deformities of the fingers", "Symphalangism affecting the phalanges of the hand", "Symphalangism of middle phalanx of finger", "Symptomatic seizures", "Syncope", "Syndactyly", "Synostosis involving bones of the hand", "Synostosis involving bones of the lower limbs", "Synostosis involving bones of the upper limbs", "Synostosis involving digits", "Synostosis of carpal bones", "Synostosis of carpals tarsals", "Synostosis of joints", "Synostosis of metacarpals metatarsals", "Synovitis", "Syringomyelia", "Systemic lupus erythematosus", "T cell lymphoma", "T lymphocytopenia", "Tachycardia", "Tachypnea", "Talipes calcaneovalgus", "Talipes equinovalgus", "Talipes equinovarus", "Talipes valgus", "Tall stature", "Tapered distal phalanges of finger", "Tapered finger", "Tarsal synostosis", "Telangiectasia", "Telangiectasia of the skin", "Telecanthus", "Temperature instability", "Temporal cortical atrophy", "Temporal optic disc pallor", "Temporal pattern", "Tendon xanthomatosis", "Tented upper lip vermilion", "Teratoma", "Testicular adrenal rest tumor", "Testicular atrophy", "Testicular dysgenesis", "Tetany", "Tetralogy of fallot", "Tetraparesis", "Tetraplegia", "Tetraplegia tetraparesis", "Thenar muscle atrophy", "Thick cerebral cortex", "Thick corpus callosum", "Thick eyebrow", "Thick hair", "Thick lower lip vermilion", "Thick nasal alae", "Thick upper lip vermilion", "Thick vermilion border", "Thickened calvaria", "Thickened cortex of long bones", "Thickened ears", "Thickened helices", "Thickened nuchal skin fold", "Thickened ribs", "Thickened skin", "Thin bony cortex", "Thin clavicles", "Thin eyebrow", "Thin nail", "Thin ribs", "Thin skin", "Thin upper lip vermilion", "Thin vermilion border", "Thinning of descemet membrane", "Third degree atrioventricular block", "Thoracic aortic aneurysm", "Thoracic hypoplasia", "Thoracic kyphoscoliosis", "Thoracic kyphosis", "Thoracic scoliosis", "Thoracolumbar kyphoscoliosis", "Thoracolumbar kyphosis", "Thoracolumbar scoliosis", "Thrombocytosis", "Thromboembolism", "Thrombophlebitis", "Thymus hyperplasia", "Thyroid adenoma", "Thyroid carcinoma", "Thyroiditis", "Tibial bowing", "Tibial torsion", "Tibialis muscle weakness", "Tics", "Tiger tail banding", "Tinnitus", "Tip toe gait", "Tissue ischemia", "Titubation", "Toe clinodactyly", "Toe syndactyly", "Toe walking", "Toenail dysplasia", "Tongue atrophy", "Tongue fasciculations", "Tongue nodules", "Tongue thrusting", "Tonic seizure", "Tooth malposition", "Torsade de pointes", "Torsion dystonia", "Total anomalous pulmonary venous return", "Toxemia of pregnancy", "Tracheal stenosis", "Tracheobronchomalacia", "Tracheoesophageal fistula", "Tracheomalacia", "Tractional retinal detachment", "Transient global amnesia", "Transient ischemic attack", "Transient neutropenia", "Transposition of the great arteries", "Tremor", "Tremor by anatomical site", "Triangular face", "Triangular mouth", "Triangular shaped phalanges of the hand", "Triceps weakness", "Trichorrhexis nodosa", "Tricuspid atresia", "Tricuspid stenosis", "Tricuspid valve prolapse", "Trigonocephaly", "Triphalangeal thumb", "Trismus", "Tritanomaly", "Trophic changes related to pain", "Truncal ataxia", "Truncal obesity", "Truncus arteriosus", "Tube feeding", "Tubulointerstitial nephritis", "Turricephaly", "Type 1 fibers relatively smaller than type 2 fibers", "Type 1 muscle fiber atrophy", "Type 2 muscle fiber atrophy", "Type 2 muscle fiber predominance", "Type i diabetes mellitus", "Type i transferrin isoform profile", "Type ii diabetes mellitus", "Type ii lissencephaly", "Type ii transferrin isoform profile", "Typical absence seizure", "U shaped upper lip vermilion", "Ulcerative colitis", "Ulnar bowing", "Ulnar claw", "Ulnar deviation of finger", "Ulnar deviation of the 2nd finger", "Ulnar deviation of the hand", "Ulnar deviation of the hand or of fingers of the hand", "Ulnar deviation of the wrist", "Uncombable hair", "Unconjugated hyperbilirubinemia", "Underdeveloped nasal alae", "Underdeveloped supraorbital ridges", "Underdeveloped tragus", "Underfolded helix", "Undetectable electroretinogram", "Undetectable light and dark adapted electroretinogram", "Undetectable visual evoked potentials", "Unexplained fevers", "Unilateral primary pulmonary dysgenesis", "Unilateral ptosis", "Unilateral renal agenesis", "Unsteady gait", "Unusual fungal infection", "Unusual infection", "Unusual infection by anatomical site", "Unusual skin infection", "Upgaze palsy", "Uplifted earlobe", "Upper airway obstruction", "Upper extremity joint dislocation", "Upper eyelid coloboma", "Upper limb amyotrophy", "Upper limb asymmetry", "Upper limb hypertonia", "Upper limb muscle weakness", "Upper limb pain", "Upper limb postural tremor", "Upper limb spasticity", "Upper limb undergrowth", "Upper motor neuron dysfunction", "Upslanted palpebral fissure", "Ureteral duplication", "Ureteral obstruction", "Ureteral stenosis", "Ureterocele", "Urethral obstruction", "Urethral stenosis", "Urethral stricture", "Urethral valve", "Uric acid nephrolithiasis", "Urinary bladder sphincter dysfunction", "Urinary glycosaminoglycan excretion", "Urinary incontinence", "Urinary retention", "Urinary tract neoplasm", "Urinary urgency", "Urogenital fistula", "Urogenital sinus anomaly", "Urticaria", "Uterine prolapse", "Uveal melanoma", "Uveitis", "Vacuolated lymphocytes", "Vaginal atresia", "Vaginal fistula", "Vaginal neoplasm", "Variable expressivity", "Varicose veins", "Vascular calcification", "Vascular dilatation", "Vascular neoplasm", "Vascular skin abnormality", "Vascular tortuosity", "Vasculitis", "Vegetative state", "Vein of galen aneurysmal malformation", "Velopharyngeal insufficiency", "Venous insufficiency", "Venous malformation", "Venous thrombosis", "Ventricular arrhythmia", "Ventricular escape rhythm", "Ventricular fibrillation", "Ventricular hypertrophy", "Ventricular preexcitation", "Ventricular septal hypertrophy", "Ventricular tachycardia", "Ventriculomegaly", "Verrucae", "Vertebral arch anomaly", "Vertebral clefting", "Vertebral compression fracture", "Vertebral fusion", "Vertebral hypoplasia", "Vertebral segmentation defect", "Vertebral wedging", "Vertical nystagmus", "Vertical supranuclear gaze palsy", "Vertigo", "Very long chain fatty acid accumulation", "Vestibular dysfunction", "Viral encephalitis", "Viral hepatitis", "Viral infection induced rhabdomyolysis", "Visceral angiomatosis", "Visual acuity test abnormality", "Visual field defect", "Visual fixation instability", "Visual hallucinations", "Visual impairment", "Visual loss", "Vitamin b12 deficiency", "Vitiligo", "Vitreoretinopathy", "Vitreous floaters", "Vitreous hemorrhage", "Vitritis", "Vocal cord paralysis", "Vocal cord paresis", "Volvulus", "Vomiting", "Waddling gait", "Weak cry", "Weak voice", "Weakness due to upper motor neuron dysfunction", "Weakness of facial musculature", "Weakness of long finger extensor muscles", "Weakness of muscles of respiration", "Weakness of the intrinsic hand muscles", "Webbed neck", "Weight loss", "Wheezing", "White forelock", "White hair", "Wide anterior fontanel", "Wide cranial sutures", "Wide intermamillary distance", "Wide mouth", "Wide nasal bridge", "Wide nasal ridge", "Wide nose", "Widely patent fontanelles and sutures", "Widely spaced incisors", "Widely spaced teeth", "Widened cerebral subarachnoid space", "Widened subarachnoid space", "Widow s peak", "Woolly hair", "Wormian bones", "Wrist flexion contracture", "Writer s cramp", "X linked dominant inheritance", "X linked recessive inheritance", "Xanthelasma", "Xanthomatosis", "Xerostomia", "Y shaped metacarpals", "Yellow white lesions of the retina", "Young adult onset", "Zollinger ellison syndrome", "Zonular cataract"], "available_proteins": ["AAAS", "AARS", "AARS2", "AASS", "ABCB1", "ABCB7", "ABCC1", "ABCD3", "ABHD12", "ACACA", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACO2", "ACOX1", "ACP2", "ACSL4", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ADA", "ADAR", "ADD1", "ADH5", "ADK", "ADNP", "ADPRHL2", "ADSL", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AKT1", "AKT2", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALG1", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANXA11", "AP1B1", "AP2M1", "AP3B1", "AP3D1", "APOL2", "APRT", "ARCN1", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARL2", "ARL3", "ARPC1B", "ASAH1", "ASNA1", "ASNS", "ASPH", "ASPM", "ATAD1", "ATAD3A", "ATIC", "ATP1A1", "ATP2A2", "ATP2C1", "ATP5A1", "ATP6", "ATP6AP1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "ATP7B", "ATRX", "ATXN10", "B4GAT1", "BAG3", "BANF1", "BAX", "BAZ1B", "BCAP31", "BCAT2", "BCL10", "BCS1L", "BLVRA", "BMS1", "BUB3", "C19orf70", "C1QBP", "C21orf59", "CAD", "CALD1", "CALR", "CAPN1", "CARS", "CARS2", "CASK", "CAST", "CBFB", "CCDC47", "CCT5", "CD2AP", "CD81", "CDC42", "CDC45", "CDC73", "CDK13", "CDK4", "CDK6", "CDKN2A", "CELF2", "CEP55", "CFL2", "CHAMP1", "CHD1", "CHD4", "CHEK2", "CHORDC1", "CHST14", "CHUK", "CISD2", "CIZ1", "CLCN7", "CLN5", "CLP1", "CLPB", "CLPP", "CLPX", "CLTC", "CNOT1", "CNP", "COA3", "COA7", "COASY", "COG7", "COL4A3BP", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COX2", "COX4I1", "COX5A", "CPNE1", "CPOX", "CPSF1", "CPT2", "CRKL", "CRTAP", "CSNK2B", "CSTB", "CTBP1", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTSA", "CTSB", "CTSC", "CUL3", "CUL4B", "CWF19L1", "CYB5R3", "CYC1", "DARS", "DARS2", "DAXX", "DCPS", "DCTN1", "DCTN4", "DCXR", "DDB1", "DDOST", "DDRGK1", "DDX3X", "DDX41", "DDX6", "DGCR8", "DHCR24", "DHFR", "DHPS", "DHX16", "DHX30", "DHX37", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIP2B", "DIS3L2", "DKC1", "DLAT", "DLD", "DLST", "DNAAF5", "DNAJB11", "DNAJB6", "DNAJC3", "DNM1", "DNM1L", "DNM2", "DNMT1", "DPF2", "DPM1", "DPP9", "DSG2", "DSP", "DST", "DYNC1H1", "DYNC1I2", "DYNLL1", "EARS2", "EBP", "ECE1", "ECHS1", "EDC3", "EEF1A2", "EEF2", "EFL1", "EFTUD2", "EHMT1", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF3F", "EIF4A3", "EIF4G1", "EIF4H", "EIF5A", "ELAC2", "ELMO2", "ELP1", "ELP2", "ELP4", "EMC1", "EMD", "EMG1", "EPB41", "EPHX2", "EPRS", "ERAL1", "ERAP1", "ERCC2", "ERLIN2", "ESS2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXOC2", "EXOC7", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EZR", "FAH", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FDFT1", "FDPS", "FDXR", "FECH", "FH", "FHL1", "FIP1L1", "FKBP10", "FKBP14", "FLCN", "FLII", "FLNA", "FLNB", "FLNC", "FMR1", "FOXC1", "FOXRED1", "FRG1", "FSCN1", "FTO", "FTSJ1", "FUS", "FXR1", "G6PD", "GAA", "GALK1", "GALM", "GALNT2", "GANAB", "GAPVD1", "GARS", "GATAD2B", "GBA", "GCDH", "GDI1", "GEMIN4", "GEMIN5", "GFM1", "GFPT1", "GGCX", "GIGYF2", "GINS1", "GLA", "GLB1", "GLDC", "GLMN", "GLRX5", "GLS", "GLUD1", "GM2A", "GMPPA", "GMPPB", "GNAI2", "GNAI3", "GNE", "GNS", "GOT2", "GPAA1", "GPD2", "GPI", "GPKOW", "GPT2", "GRHPR", "GSR", "GSS", "GSTM3", "GTF2I", "GUSB", "GYG1", "GYS1", "H2AFY", "HADH", "HADHA", "HADHB", "HCCS", "HCFC1", "HELLS", "HERC2", "HEXA", "HEXB", "HIBCH", "HIST1H1E", "HK1", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HMGA1", "HMGB3", "HMGCL", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HPRT1", "HPS6", "HSD17B10", "HSD17B4", "HSPA9", "HSPB1", "HSPD1", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IFT27", "IGBP1", "IGF1R", "IGF2BP2", "IGF2R", "IMPAD1", "INF2", "IRF2BPL", "IRS4", "ISCU", "ITCH", "ITPA", "IVD", "JUP", "KARS", "KDM1A", "KDM3B", "KDSR", "KIF11", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF4A", "KIFBP", "KLC2", "KMT2A", "L2HGDH", "LAMTOR2", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDHA", "LEMD3", "LETM1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMNA", "LMNB1", "LMNB2", "LONP1", "LRBA", "LRPAP1", "LRPPRC", "LSS", "LZTFL1", "MACF1", "MAGED2", "MAP1B", "MAP2K1", "MAP2K2", "MAP3K7", "MAPK1", "MAPRE2", "MARS", "MAT2A", "MATR3", "MCCC1", "MCCC2", "MCM2", "MCM4", "MCM5", "MCM6", "MCM7", "MDH1", "MDH2", "MECP2", "MED17", "MED25", "MESD", "MFF", "MFN2", "MIA3", "MICU1", "MID1", "MIF", "MIPEP", "MMAB", "MOGS", "MPG", "MPI", "MRE11", "MRPL12", "MRPL3", "MRPL44", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS28", "MRPS34", "MRPS35", "MRPS7", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTAP", "MTCH1", "MTHFD1", "MTOR", "MTPAP", "MTX2", "MUT", "MVD", "MVK", "MYH9", "MYO6", "NAA10", "NAA15", "NADK2", "NAGLU", "NANS", "NARS", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPH", "NCDN", "NCSTN", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA6", "NDUFA8", "NDUFA9", "NDUFAF4", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NEFL", "NEK9", "NELFA", "NEMF", "NFS1", "NHLRC2", "NHP2", "NNT", "NONO", "NOP56", "NOVA2", "NPC1", "NPM1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSUN2", "NT5C2", "NT5C3A", "NUBPL", "NUMA1", "NUP107", "NUP133", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP37", "NUP62", "NUP85", "NUP88", "NUP93", "NXN", "OAT", "OCRL", "OGDH", "OGT", "OPA1", "OPA3", "OSGEP", "OTULIN", "P3H1", "P4HB", "PABPN1", "PAFAH1B1", "PALLD", "PARK7", "PARN", "PBRM1", "PC", "PCBD1", "PCCA", "PCCB", "PCK2", "PCNA", "PDCD6", "PDE6D", "PDHA1", "PDHB", "PDK3", "PDXK", "PEPD", "PEX14", "PEX19", "PEX5", "PFKM", "PFN1", "PGK1", "PGM1", "PGM3", "PHB", "PHF6", "PHGDH", "PHIP", "PICALM", "PIGK", "PIGS", "PIGU", "PIK3C2A", "PISD", "PITRM1", "PLD3", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMVK", "PNP", "PNPLA6", "PNPLA8", "PNPO", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLE", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR3A", "PON2", "POP1", "POR", "PPA2", "PPIB", "PPIL1", "PPOX", "PPP1CB", "PPP2R1A", "PPP2R1B", "PPP2R5D", "PPP3CA", "PPT1", "PQBP1", "PREPL", "PRKACA", "PRKAR1A", "PRKCSH", "PRKDC", "PRKRA", "PRPF3", "PRPF31", "PRPF4", "PRPF6", "PRPF8", "PSAP", "PSAT1", "PSMB4", "PSMC3", "PSMD12", "PSMG2", "PTCD3", "PTDSS1", "PTPN1", "PTPN11", "PTRH2", "PUF60", "PUM1", "PURA", "PUS1", "PUS7", "PYCR1", "PYCR2", "PYGL", "QARS", "QDPR", "QRICH1", "QRSL1", "RAB18", "RAB3GAP1", "RAB3GAP2", "RAB7A", "RAC1", "RAD21", "RAD50", "RANBP2", "RAPGEF2", "RARS", "RASA1", "RBM10", "RBM12", "RBM28", "RBM8A", "RBMX", "RDH11", "RDX", "RECQL4", "RFC1", "RFC2", "RHOA", "RINT1", "RNASEH2A", "RNASEH2B", "RNASET2", "RP2", "RPL10", "RPL11", "RPL13", "RPL15", "RPL18", "RPL21", "RPL26", "RPL27", "RPL31", "RPL35", "RPL35A", "RPL5", "RPS10", "RPS14", "RPS15A", "RPS17", "RPS19", "RPS20", "RPS23", "RPS24", "RPS26", "RPS28", "RPS6KA3", "RPS7", "RPSA", "RREB1", "RTN2", "RTN4IP1", "SAMHD1", "SARS", "SARS2", "SBDS", "SC5D", "SCAF1", "SCARB2", "SCO1", "SCO2", "SCP2", "SDHA", "SDHB", "SEC23A", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEPT9", "SERPINB6", "SERPINH1", "SET", "SF3B1", "SF3B4", "SFXN4", "SGPL1", "SH3GL1", "SHMT2", "SHOC2", "SIGMAR1", "SIN3A", "SKIV2L", "SLC12A2", "SLC16A1", "SLC19A1", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC27A4", "SLC9A3R1", "SLTM", "SMARCA4", "SMARCAD1", "SMARCB1", "SMARCC2", "SMARCE1", "SMC1A", "SMC3", "SMCHD1", "SMN1*", "SMPD4", "SMS", "SNAP29", "SNRNP200", "SNRPE", "SOAT1", "SON", "SORD", "SPART", "SPECC1L", "SPEN", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SRCAP", "SRP54", "SRP72", "SSBP1", "SSR4", "STAG2", "STAMBP", "STARD7", "STAT1", "STAT3", "STK4", "STT3A", "STT3B", "STUB1", "SUCLA2", "SUCLG1", "SUZ12", "SYNE2", "TACO1", "TAF15", "TALDO1", "TARDBP", "TARS", "TARS2", "TBCD", "TBCE", "TBL2", "TCOF1", "TDP2", "TECR", "TELO2", "TERF2IP", "TFAM", "TFG", "TFRC", "TIA1", "TIMM22", "TIMM50", "TKT", "TMCO1", "TMEM126A", "TMEM199", "TMEM43", "TMPO", "TMPO", "TMTC3", "TMX2", "TOE1", "TOMM40", "TOP2A", "TOR1AIP1", "TP53", "TPI1", "TPM3", "TPP1", "TPP2", "TRAPPC11", "TRAPPC4", "TRIM28", "TRIP12", "TRIP13", "TRMT10C", "TSC2", "TSFM", "TSPYL1", "TTC19", "TTC37", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUFM", "TWNK", "UBA1", "UBE4A", "UBTF", "UFC1", "UFD1", "UFSP2", "UGDH", "UGP2", "UMPS", "UNC119", "UNC45A", "UNG", "UPF3B", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USMG5", "USP7", "USP9X", "VAC14", "VAMP7", "VAPB", "VARS1", "VARS2", "VCL", "VCP", "VIM", "VPS13A", "VPS33A", "VPS35", "VPS4A", "VPS51", "VPS53", "VRK1", "WARS", "WBP11", "WDR1", "WDR36", "WDR73", "WFS1", "WIPI2", "WRAP53", "XPNPEP3", "XRCC1", "YARS", "YARS2", "YME1L1", "YWHAE", "YWHAG", "ZC3H14", "ZCCHC8", "ZFR", "ZMPSTE24", "ZNF687", "ZPR1"], "leading_proteins": ["AARS2", "AASS", "ABCB7", "ABCC1", "ABHD12", "ACADVL", "ACOX1", "ACTN2", "AIP", "AK2", "AKT1", "AKT2", "ALDH18A1", "ALDH3A2", "ALDH5A1", "ANKLE2", "ANLN", "AP1B1", "APRT", "ARCN1", "ARHGDIA", "ASNA1", "ASPM", "ATAD1", "ATAD3A", "ATP6", "ATP6V1B2", "ATP6V1E1", "ATRX", "BANF1", "BAZ1B", "BCL10", "BCS1L", "BMS1", "C19orf70", "C21orf59", "CALR", "CAPN1", "CARS", "CBFB", "CCDC47", "CDC42", "CDC73", "CDK13", "CDKN2A", "CEP55", "CHEK2", "CHUK", "CISD2", "CLP1", "CNOT1", "COA3", "COASY", "COL4A3BP", "COLGALT1", "COPA", "COX2", "COX4I1", "CPOX", "CPT2", "CTNNB1", "CTSA", "CUL3", "CUL4B", "DAXX", "DDB1", "DDOST", "DDRGK1", "DDX41", "DGCR8", "DHCR24", "DHFR", "DHX30", "DHX37", "DIAPH3", "DIP2B", "DKC1", "DLAT", "DLST", "DNAAF5", "DNAJB6", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DPM1", "DSP", "EARS2", "EDC3", "EIF2B1", "EIF2B3", "EIF2B4", "EIF2B5", "EIF3F", "EIF4A3", "EIF4G1", "EIF4H", "ELMO2", "ELP1", "ELP2", "ERAP1", "ERCC2", "ETFA", "ETFB", "EXOC2", "EXOC7", "EXOSC2", "EXOSC9", "FANCD2", "FANCI", "FAR1", "FASN", "FDXR", "FH", "FKBP14", "FLNA", "FLNB", "FSCN1", "FTO", "GAA", "GALK1", "GALM", "GBA", "GCDH", "GEMIN4", "GLRX5", "GNAI2", "GPT2", "GTF2I", "HADH", "HADHB", "HIST1H1E", "HK1", "HLA-B", "HMGA1", "HMOX1", "HNRNPU", "HPRT1", "HSD17B10", "HSPB1", "IARS", "IBA57", "IGF2BP2", "IMPAD1", "IRF2BPL", "ITCH", "JUP", "KARS", "KDM1A", "KDSR", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIFBP", "KMT2A", "LAMTOR2", "LBR", "LETM1", "LLGL1", "LONP1", "LRBA", "LRPAP1", "LRPPRC", "LZTFL1", "MACF1", "MAP2K1", "MAP2K2", "MAP3K7", "MAPK1", "MAT2A", "MATR3", "MCCC2", "MCM4", "MDH1", "MDH2", "MECP2", "MED25", "MFN2", "MIA3", "MIPEP", "MOGS", "MPG", "MRE11", "MRPL12", "MRPL44", "MRPS23", "MRPS25", "MRPS28", "MRPS35", "MSH2", "MSMO1", "MSN", "MTOR", "MTX2", "MUT", "MVK", "MYH9", "NADK2", "NAGLU", "NCAPD3", "NCSTN", "NDUFA11", "NDUFA4", "NDUFA8", "NDUFA9", "NDUFB11", "NDUFB3", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV2", "NECAP1", "NEFL", "NNT", "NONO", "NSDHL", "NSMCE2", "NUBPL", "NUP188", "NUP214", "OAT", "OCRL", "OGT", "P3H1", "PABPN1", "PALLD", "PCBD1", "PCK2", "PDCD6", "PDHB", "PDXK", "PEPD", "PEX5", "PGM3", "PHF6", "PHGDH", "PIGK", "PITRM1", "PLEC", "PLOD1", "PMPCA", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLE", "POLR1B", "POLR1C", "POLR2A", "PON2", "POR", "PPIL1", "PPOX", "PPP2R1A", "PPP2R5D", "PPP3CA", "PQBP1", "PRKACA", "PRKAR1A", "PSAT1", "PTCD3", "PTRH2", "PUM1", "PUS1", "PYCR1", "QRSL1", "RAB3GAP2", "RARS", "RASA1", "RBM10", "RBM8A", "RDH11", "RECQL4", "RFC2", "RP2", "RPL10", "RPL27", "RPL31", "RPL35", "RPL35A", "RPS14", "RPS15A", "RPS19", "RPS20", "RPS7", "RPSA", "SCAF1", "SCARB2", "SCO2", "SDHA", "SDHB", "SERPINH1", "SF3B4", "SFXN4", "SGPL1", "SHMT2", "SHOC2", "SIGMAR1", "SIN3A", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A13", "SLC25A15", "SLC25A21", "SLC25A26", "SLC25A32", "SLC27A4", "SLC9A3R1", "SLTM", "SMARCC2", "SMC1A", "SMC3", "SMPD4", "SNAP29", "SOAT1", "SON", "SPECC1L", "SPEN", "SPTBN1", "SRP54", "STAG2", "STAT3", "STK4", "STT3A", "STT3B", "STUB1", "TALDO1", "TARDBP", "TARS", "TBCE", "TBL2", "TCOF1", "TDP2", "TELO2", "TFAM", "TFRC", "TIA1", "TIMM22", "TKT", "TMEM43", "TOR1AIP1", "TP53", "TPI1", "TPM3", "TPP1", "TRAPPC11", "TSPYL1", "TTC37", "TUBB2B", "TUBB4A", "TUBB4B", "TUBGCP2", "UBA1", "UFC1", "UFD1", "UGDH", "UGP2", "UNC119", "UNC45A", "UNG", "UQCRB", "UQCRQ", "UROD", "VAC14", "VAMP7", "VARS2", "VCP", "VPS13A", "VPS33A", "VRK1", "WBP11", "WDR1", "WFS1", "YARS", "YARS2", "YME1L1", "ZMPSTE24", "ZPR1"]} \ No newline at end of file diff --git a/msigdb_kegg/advanced/idx2term.json b/msigdb_kegg/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..80492ccda267d051ad2be449bc623c166c76881a --- /dev/null +++ b/msigdb_kegg/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Alzheimers disease", "1": "Amyotrophic lateral sclerosis als", "2": "Huntingtons disease", "3": "Ribosome"} \ No newline at end of file diff --git a/msigdb_kegg/advanced/plot_0.png b/msigdb_kegg/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..16154cb5b30e4c807391f8ba33bb87af0f3241de --- /dev/null +++ b/msigdb_kegg/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:dcf0b02e0a0fe38a59fb9993264348974b6768e37f89130958ef7c1098711665 +size 208435 diff --git a/msigdb_kegg/advanced/plot_1.png b/msigdb_kegg/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..a2165e0fb01b88ed12c8819668f750ad0a03e63b --- /dev/null +++ b/msigdb_kegg/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:314dcd629583170a848f530690aa8b5db29047dddfe4afb8e1a063f6c4cd2f8e +size 197217 diff --git a/msigdb_kegg/advanced/plot_2.png b/msigdb_kegg/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..570b2002d32e814e0ae9f4b14b8682aed2dad95c --- /dev/null +++ b/msigdb_kegg/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ae64ac87c47cb5cf9250102fd66e14b4701e227363097c128049e0a17766d40f +size 212890 diff --git a/msigdb_kegg/advanced/plot_3.png b/msigdb_kegg/advanced/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..f6e1c0e6b81059f62f60b00676765f817932169d --- /dev/null +++ b/msigdb_kegg/advanced/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5327acb260a66f28e68d06b2fb904f2311ce0da29ff6faa0a9089a6f1251f66e +size 191282 diff --git a/msigdb_kegg/basic/idx2term.json b/msigdb_kegg/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..a2d88d4ef5deab9f58bb39e63bbe496e44868bb5 --- /dev/null +++ b/msigdb_kegg/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Alzheimers disease", "1": "Amyotrophic lateral sclerosis als", "2": "Huntingtons disease", "3": "Ribosome", "4": "Vegf signaling pathway", "5": "Oxidative phosphorylation", "6": "Parkinsons disease", "7": "Toll like receptor signaling pathway", "8": "Ppar signaling pathway", "9": "Apoptosis", "10": "N glycan biosynthesis", "11": "Vasopressin regulated water reabsorption", "12": "Pyrimidine metabolism", "13": "Epithelial cell signaling in helicobacter pylori infection", "14": "Gap junction", "15": "Pathways in cancer", "16": "Wnt signaling pathway", "17": "Systemic lupus erythematosus", "18": "Cytosolic dna sensing pathway", "19": "Proteasome", "20": "Vascular smooth muscle contraction"} \ No newline at end of file diff --git a/msigdb_kegg/basic/plot_0.png b/msigdb_kegg/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..7db21d006b0cbe527ff2bced2254158de6ba3954 --- /dev/null +++ b/msigdb_kegg/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4e8db2e361b39d2957b71aa869151f09dd914956efb5e9cfb240f4e960aff3a5 +size 141787 diff --git a/msigdb_kegg/basic/plot_1.png b/msigdb_kegg/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..607b4eaf047218b532d42c0854441703cfea1356 --- /dev/null +++ b/msigdb_kegg/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:622e9970244ec4313ca779087b611a38c045f5a20dcf82f1afd42c9b8b344471 +size 139858 diff --git a/msigdb_kegg/basic/plot_10.png b/msigdb_kegg/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..6ef895ac5d1ba91692b3f2066ba387eb48488f2e --- /dev/null +++ b/msigdb_kegg/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:449967f11ca0b3b0a1885595d9c85c124f7a3fecf65052bf0bc00b571e924ab2 +size 132584 diff --git a/msigdb_kegg/basic/plot_11.png b/msigdb_kegg/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..e22e64f49a782cec81c684bad8e0309bdd12893e --- /dev/null +++ b/msigdb_kegg/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a9cd7c9d61d964d5822a7a776157d8462ef7968d417bd77d5437509a3fe0564a +size 151546 diff --git a/msigdb_kegg/basic/plot_12.png b/msigdb_kegg/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..4e41592a98f6694424d6cbb66b728b8354acbe55 --- /dev/null +++ b/msigdb_kegg/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:41fca7c657d916cfa432c8a592f56e919ef5462b835547f6885853adb3a77d4e +size 143529 diff --git a/msigdb_kegg/basic/plot_13.png b/msigdb_kegg/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..186bb4817c8b709f01de662b08a0d270092652a1 --- /dev/null +++ b/msigdb_kegg/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c9850caef78e159bbbf287b98be61e82096bb501eee6bee805c5a002d6bccdd3 +size 150573 diff --git a/msigdb_kegg/basic/plot_14.png b/msigdb_kegg/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..bedccf84ebce244ed24b607227af890e9b494470 --- /dev/null +++ b/msigdb_kegg/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8a904e3053989dc84f214371b8353e466046d750d41107d820477ac1c3a63e13 +size 142869 diff --git a/msigdb_kegg/basic/plot_15.png b/msigdb_kegg/basic/plot_15.png new file mode 100644 index 0000000000000000000000000000000000000000..0c71c7a88b6881e80c6e82ff46f5849a91d72346 --- /dev/null +++ b/msigdb_kegg/basic/plot_15.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b5e81a64b51757fa436d77b90838d6f797249ca73e30c666b480783cc83f54e5 +size 146037 diff --git a/msigdb_kegg/basic/plot_16.png b/msigdb_kegg/basic/plot_16.png new file mode 100644 index 0000000000000000000000000000000000000000..d680731b22a59bb768fdcf3613a60d457df1d52c --- /dev/null +++ b/msigdb_kegg/basic/plot_16.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:21d2153fdbcdabc96a8daa879ec7ad52a5bb7704b21efb73af1dd681fb6375e2 +size 147337 diff --git a/msigdb_kegg/basic/plot_17.png b/msigdb_kegg/basic/plot_17.png new file mode 100644 index 0000000000000000000000000000000000000000..75865f79e70c85fa465883f3ff6e0e436b5c1ce9 --- /dev/null +++ b/msigdb_kegg/basic/plot_17.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:df673e703dee1676dda43e756695f92179e3265166cc229f469f83a4691fba4c +size 142473 diff --git a/msigdb_kegg/basic/plot_18.png b/msigdb_kegg/basic/plot_18.png new file mode 100644 index 0000000000000000000000000000000000000000..e32d7a985d88285cf4f6232948e6e26b999c120e --- /dev/null +++ b/msigdb_kegg/basic/plot_18.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3d5559f7f8370485ab3ec460539caabda6746e718494aa36852ba3bd8ec3447f +size 143130 diff --git a/msigdb_kegg/basic/plot_19.png b/msigdb_kegg/basic/plot_19.png new file mode 100644 index 0000000000000000000000000000000000000000..baec15f60e7e6626cb75cf997c36bceb54ae4f7f --- /dev/null +++ b/msigdb_kegg/basic/plot_19.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:47525ea4f344594b31fd2fd889df8a9c71e936fe764e9d476ca4d7653087c380 +size 142628 diff --git a/msigdb_kegg/basic/plot_2.png b/msigdb_kegg/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..e8c6f83e94b1e67e081acbe986ef6a6c04c4520c --- /dev/null +++ b/msigdb_kegg/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:95743e105adda289551dee67f5d2373f8430160e542a03bdc63783e6f4a3cc54 +size 139661 diff --git a/msigdb_kegg/basic/plot_20.png b/msigdb_kegg/basic/plot_20.png new file mode 100644 index 0000000000000000000000000000000000000000..ed7e4b876530aea6d24cd5387dbd25f53e7014da --- /dev/null +++ b/msigdb_kegg/basic/plot_20.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a3723cdd02dd735b88c75f365111e78556ed5e18c9fc2ec72a09912754b88074 +size 151846 diff --git a/msigdb_kegg/basic/plot_3.png b/msigdb_kegg/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..27a618b836ea0f84f3ca3f5b9a525dc1b357ba86 --- /dev/null +++ b/msigdb_kegg/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9d183084e1aa53abb93b444b7136c750e585f264ae089fdf6abd84ab26d8f377 +size 136380 diff --git a/msigdb_kegg/basic/plot_4.png b/msigdb_kegg/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..e51aed451e3907d373c5ed2270a9278e25f8e4d0 --- /dev/null +++ b/msigdb_kegg/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7a09b96d709aa05ec7f350208ed966dcd05ff16d725e786411aee25543147726 +size 128524 diff --git a/msigdb_kegg/basic/plot_5.png b/msigdb_kegg/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..9dc50c34cae0781146f1b99ad0274a3f36788b96 --- /dev/null +++ b/msigdb_kegg/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0f3e024abebd3c831e7252e979c43770217ab7fad3df6889fbb48e3dfe5f2c9d +size 142525 diff --git a/msigdb_kegg/basic/plot_6.png b/msigdb_kegg/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..9969ff826eec91c863cfb9730116d454b12b04fa --- /dev/null +++ b/msigdb_kegg/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a666affbbc27d9b69df19ec106eac6ab2fd625abc851d61f0884de89a33510d7 +size 140505 diff --git a/msigdb_kegg/basic/plot_7.png b/msigdb_kegg/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..2198c2152ec41a0d6be6b24eca64749a2a107770 --- /dev/null +++ b/msigdb_kegg/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b2e3fd505eeec447502dd3e70db43f4ed83e83d2ec61c5b6b497964afbf3588b +size 138829 diff --git a/msigdb_kegg/basic/plot_8.png b/msigdb_kegg/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..519ee456f169a85dd58ac9208fbe1f3f2dcaf701 --- /dev/null +++ b/msigdb_kegg/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c0bf10a798241d8bac4594fd6481f35daeec369ce373077109b50036a87750e1 +size 135286 diff --git a/msigdb_kegg/basic/plot_9.png b/msigdb_kegg/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..8c311a344266ec9b4a2843bd0a335c7fe31bc62b --- /dev/null +++ b/msigdb_kegg/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d13e1a596fc15301deb7922cf830eb861dd3a1aa237605cf93dd87369abb30f2 +size 138895 diff --git a/msigdb_kegg/consensus.joblib b/msigdb_kegg/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..97ff895ce02a23b13edd908b19285cc2ac07d5c6 --- /dev/null +++ b/msigdb_kegg/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:67cae664a51de2fc0dc99f556de88e08e906e9a1d576756014221fe05f019534 +size 69061 diff --git a/msigdb_kegg/df_merge.tsv b/msigdb_kegg/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..5a49ba5b39feece013d70ea02f95413f3e9f4be2 --- /dev/null +++ b/msigdb_kegg/df_merge.tsv @@ -0,0 +1,6 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Alzheimers disease 24 53 2.5157067818072942 0.0118793968395052 16.135922330097088 58.91990291262136 0.6161331149111849 0.4362889390372475 6.737157569069632 4.882193919366804 1.448905264905826 0.3805753751040122 1.0 0.4657724234841013 0.1222711157267288 0.09131905745361 0.0101627652477285 +Amyotrophic lateral sclerosis als 7 13 2.35209766867597 0.0186678725481281 2.895631067961165 10.6626213592233 0.370852905277699 0.5967997021777554 1.8185346549003725 1.5169786407319608 0.6928917746074938 0.2858383041361014 1.0 1.0 0.047703557684962 0.0118014485318642 0.00034680499544 +Huntingtons disease 14 71 2.277096847552833 0.0227804429122311 19.631067961165048 76.91504854368932 0.635715043905642 0.4301008974270168 9.08454389027927 5.4148363920790175 1.5734816663041495 0.3870978376334237 1.0 0.1552744972094417 0.0486716963322586 0.0085900719030575 0.004910373915656 +Ribosome 35 71 2.1333045314800905 0.0328997527358938 37.58980582524272 71.83252427184466 -1.1465156070967828 0.3112763158975234 13.159558265713326 1.6746570252811466 2.1898923040449123 0.3742528198975103 1.0 1.0 1.0 0.0477734380813384 0.0001567045385923 +Base excision repair 3 15 2.097316909305123 0.0359655309834314 5.786407766990291 16.211165048543688 -0.2730268248762191 0.5152500921911025 3.196328249777864 2.273009980360234 1.0166543179529104 0.3267952106522383 1.0 0.1484538203623246 0.2705199318339872 0.007975933763165 0.0765751187554357 diff --git a/msigdb_kegg/metrics.json b/msigdb_kegg/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..5e19a00a374d0d24cd0ad9e4e13d3c8dc63091a1 --- /dev/null +++ b/msigdb_kegg/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2772, + "annotations_size": 178, + "title": "Average number of proteins per term", + "value": 15.438202247191011 +} \ No newline at end of file diff --git a/msigdb_kegg/paths.json b/msigdb_kegg/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..329d884b4ae957216943e90575bb35e7da89ee1f --- /dev/null +++ b/msigdb_kegg/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_kegg/fragment/C321/C321_val_log2fc"} \ No newline at end of file diff --git a/msigdb_kegg/result.tsv b/msigdb_kegg/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..fed30a93de9d90e5defc7fadfd0d00e75a7b6565 --- /dev/null +++ b/msigdb_kegg/result.tsv @@ -0,0 +1,82 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Alzheimers disease 0.528113486480525 2.5157067818072942 0.0118793968395052 0.8808286238288018 0.3020760910617044 53 P14927,Q08209,Q9UHD1,P00846,O75947,P51970,P14735,Q92542,O14949,P13073,Q9UDW1,O75489,P15954,Q16795,P04406,Q16718,P06576,P07384,O75306,P09669,P36542,O43676,O75251,P42574 24 +Amyotrophic lateral sclerosis als 0.7446046896077505 2.35209766867597 0.0186678725481281 0.9650657780523918 0.4153601641958521 13 P07197,P07196,Q08209,Q9BUN8,P42574,Q9UER7,P20339 7 +Huntingtons disease 0.4617775075199596 2.2770968475528335 0.0227804429122311 0.9834574412431492 0.4505465375974603 71 P13073,P09669,P51970,P19388,Q9UDW1,P42574,O75489,Q96ST3,P14927,O43676,P00846,P04179,O94973,O14949 14 +Ribosome 0.4484215958295226 2.1333045314800905 0.0328997527358938 0.9974062626830482 0.457276036789343 71 P62906,P47914,P18077,P62249,P62910,Q9Y3U8,P62899,P62753,P62424,P62841,P32969,P63173,P15880,P62081,P30050,P62861,P62241,P35268,P62829,P62244,P62269,P39019,P62750,P61247,P08865,P62277,P05388,P46781,P46779,P61353,P42766,P18124,P26373,P05387,P61254 35 +Base excision repair 0.6599203762525024 2.097316909305123 0.0359655309834314 0.998526072571738 0.457276036789343 15 P18858,P13051,Q07864 3 +Adherens junction 0.5745337500696843 1.9546769034523657 0.0506212178824734 0.9999035649745712 0.476427623054796 23 P35609,Q9UQB8,Q9NWH9 3 +Vegf signaling pathway 0.6264567796541612 1.883149883545348 0.0596800586052055 0.9999824989122666 0.4828659287148448 14 P31749,P31751,Q08209,P04792,P36507 5 +Acute myeloid leukemia 0.6862660301766451 1.80672940689573 0.0708044802405989 0.9999978959063384 0.5203413671863384 11 P14923,P36507,P31751,P31749 4 +Oxidative phosphorylation 0.4410046280477168 1.752451589601044 0.0796961871641026 0.9999996200229252 0.5240443272109137 56 P36543,P14927,P00846,O75947,P51970,Q86Y39,O14949,P13073,P21281,Q9UDW1,O75489,P15954,Q16795,P56385,Q16718,P06576,O75306,P09669,P36542,P21283,O43676,O75251 22 +Abc transporters 0.7933670416501055 1.7434496024844044 0.0812551103036209 0.9999997190049392 0.5240443272109137 6 P33527,O75027 2 +Parkinsons disease 0.4468236508368505 1.7336812337556613 0.0829746580483461 0.9999997986840974 0.5240443272109137 51 P14927,P00846,O75947,P51970,O14949,P13073,Q9UDW1,O75489,P15954,Q16795,Q16718,P05141,P06576,O75306,P09669,P36542,O43676,O75251,P42574 19 +Homologous recombination 0.6791272674093036 1.6630245028472046 0.0963075307977296 0.9999999851516552 0.5240443272109137 10 Q04837,P35244 2 +Toll like receptor signaling pathway 0.6109731836664807 1.5482452060059964 0.1215632712476146 0.999999999904398 0.610517550815913 12 O43318,P31749,Q15750,P31751,P36507 5 +Rna polymerase 0.6500569420422692 1.5264198646624292 0.1269053335965662 0.9999999999677212 0.610517550815913 10 P19388 1 +Proximal tubule bicarbonate reclamation 0.70917484227514 1.4979957648251945 0.1341343508142098 0.9999999999926515 0.6283135380244568 7 Q16822 1 +Nucleotide excision repair 0.5063697724522644 1.378918789863261 0.1679197941407433 0.999999999999994 0.6793118944784616 19 P18858,P35244 2 +Colorectal cancer 0.5260125683502752 1.326925895711866 0.1845331972128447 0.9999999999999998 0.6988704064656676 14 P31751,P31749 2 +Glycerophospholipid metabolism 0.5587365090603835 1.2802615547247458 0.2004531638539988 1.0 0.7138793823635914 12 Q8NCC3,P35790 2 +Endometrial cancer 0.5957160248330639 1.2687269283242402 0.2045384747221525 1.0 0.7138793823635914 10 P31751,P31749 2 +Fc epsilon ri signaling pathway 0.5904944348604146 1.2438909493747303 0.2135397008160038 1.0 0.714302015602092 10 P36507,P31751,P31749 3 +Alpha linolenic acid metabolism 0.816901408450698 1.2077570830618702 0.2271407138791046 1.0 0.7157387539593353 3 O15254,Q15067 2 +Ppar signaling pathway 0.487737776621356 1.156411926997846 0.2475127053510655 1.0 0.7157387539593353 16 Q15067,O15254,Q16822,Q01469,P23786 5 +Apoptosis 0.481572075942655 1.1520457776645792 0.2493022626150494 1.0 0.7157387539593353 17 O94919,P31749,P31751,Q08209,Q9UHD1,P17612,P42574,P10644 8 +B cell receptor signaling pathway 0.5046591172835242 1.0989918762657922 0.271771609355494 1.0 0.7409033948631124 13 Q08209,P31751,P31749 3 +N glycan biosynthesis 0.5418207827204802 1.098361632323691 0.2720466091360511 1.0 0.7409033948631124 11 P04843,P46977,Q8TCJ2,O60762,P04844 5 +Renal cell carcinoma 0.4599058689932812 1.092264204516878 0.2747169891065473 1.0 0.7409033948631124 19 Q9NWH9,P31751,P36507,P31749 4 +Regulation of actin cytoskeleton 0.3752739108865689 1.0218296340763673 0.3068615410153605 1.0 0.7803050614390596 45 P35609,Q9UQB8 2 +Adipocytokine signaling pathway 0.4594395728284007 0.972775755973552 0.3306647645861649 1.0 0.8113439673061164 15 Q16822,P40763,P31751,P31749 4 +Ether lipid metabolism 0.6183034477678536 0.9665616398395028 0.3337632188397941 1.0 0.8113439673061164 5 Q15102 1 +Tight junction 0.3849688115667928 0.9596504397945425 0.3372311741475968 1.0 0.8113439673061164 35 P35609,P04899,Q96A65,P31749 4 +Dna replication 0.4067604908874681 0.9504996863605084 0.3418584131907793 1.0 0.8113439673061164 29 P18858,P35244,Q07864 3 +Jak stat signaling pathway 0.5687414775250743 0.9019665276003288 0.3670746489568603 1.0 0.8275861670578202 7 Q92783,P31751,P31749 3 +Cardiac muscle contraction 0.4287339846408863 0.9016847371882144 0.3672243630584937 1.0 0.8275861670578202 19 Q9UDW1,P09669,P14927,O14949 4 +T cell receptor signaling pathway 0.4283946885560582 0.8996297230385747 0.3683173340017509 1.0 0.8275861670578202 19 Q08209,O43318,P31751,P31749 4 +P53 signaling pathway 0.4402997717001322 0.8655482578984498 0.3867379408997395 1.0 0.8275861670578202 15 Q9Y3B8,P14635 2 +Non small cell lung cancer 0.4577807535726089 0.8503300851722354 0.3951415946132295 1.0 0.8275861670578202 13 Q13043,P31751,P31749 3 +Chemokine signaling pathway 0.4025786775730882 0.8255057536022319 0.4090845175370798 1.0 0.8275861670578202 23 P63218,P04899,P31751,P31749 4 +Vasopressin regulated water reabsorption 0.4323304520116767 0.821379874811498 0.4114299233046636 1.0 0.8275861670578202 15 Q9UJW0,Q14204,P52565,O43237,P17612,P20339 6 +Melanoma 0.4679453597776538 0.8172368568922499 0.4137930835289101 1.0 0.8275861670578202 12 Q9NWH9,P31751,P31749 3 +Phosphatidylinositol signaling system 0.538888136691225 0.7787141287616017 0.4361481314018587 1.0 0.8523299571086067 7 O95674 1 +Mismatch repair 0.4118303922878629 0.7718074317443939 0.4402284894389585 1.0 0.8523299571086067 18 P18858,P35244 2 +Regulation of autophagy 0.6525391504124551 0.6818451120464636 0.4953368954056332 1.0 0.8876665903395422 4 Q9Y4P1 1 +Axon guidance 0.391717478368324 0.6817716830141995 0.4953833324120811 1.0 0.8876665903395422 19 P04899,P20936,Q9NWH9 3 +Prostate cancer 0.401933308925911 0.6713649881846008 0.5019880433753943 1.0 0.8876665903395422 16 P31751,P31749 2 +Porphyrin and chlorophyll metabolism 0.4228717057431173 0.6713333807494752 0.5020081740784597 1.0 0.8876665903395422 13 P30519,P09601 2 +Nod like receptor signaling pathway 0.4668954390105009 0.668717053978595 0.5036759866533358 1.0 0.8876665903395422 10 O43318,Q15750 2 +Pyrimidine metabolism 0.3337121956265014 0.6571685144148541 0.511072568266522 1.0 0.889401764266517 40 O15160,P19388,Q9H9Y6,O95602,Q14181,Q9NRF8,P30085,Q9H0P0,Q9BZX2,Q16881,Q07864 11 +Nicotinate and nicotinamide metabolism 0.5196091154506959 0.6362972771886644 0.5245826793092254 1.0 0.889401764266517 6 Q9BQG2,P43490 2 +Melanogenesis 0.4723464739753544 0.632234508651528 0.527233651061467 1.0 0.889401764266517 9 P04899 1 +Bladder cancer 0.4980380956299078 0.6160779471048524 0.537843076141518 1.0 0.889401764266517 7 P42771,P36507 2 +Arrhythmogenic right ventricular cardiomyopathy arvc 0.4242917672924052 0.605800707184075 0.5446471000752975 1.0 0.8894237047101188 12 P35609,P14923 2 +Erbb signaling pathway 0.4062478284503927 0.5893183841323504 0.5556477146421537 1.0 0.8910974172258548 13 P31751,P31749 2 +Epithelial cell signaling in helicobacter pylori infection 0.3659819219774277 0.5867079879692731 0.5573998420382753 1.0 0.8910974172258548 21 P21281,P36543,Q16539,P21283,Q9NWH9,Q9Y624,P42574 7 +Gnrh signaling pathway 0.4710456676156785 0.5735939706525608 0.5662425927643744 1.0 0.8910974172258548 8 Q16539,P17612,P36507 3 +Gap junction 0.3776478923564544 0.5597930181561003 0.5756206264518402 1.0 0.8910974172258548 17 P68371,P04350,Q07157,Q13885,P36507,P17612,P04899 7 +Insulin signaling pathway 0.3329198586630919 0.5557713197086168 0.5783671941486641 1.0 0.8910974172258548 35 Q16822,P31751,P31749 3 +Prion diseases 0.470572752692646 0.5124920443265486 0.6083066868134785 1.0 0.9176151716338914 7 P17612,Q02750,P36507 3 +Small cell lung cancer 0.4311788097986448 0.4235768086280514 0.6718744715855403 1.0 0.9644649672760174 8 P31749 1 +Focal adhesion 0.3217124861173595 0.4033204801699932 0.6867124773120603 1.0 0.9699307028171362 31 P35609,Q9NWH9,P31749 3 +Long term depression 0.3856356640490975 0.3830196267940516 0.7017052116751112 1.0 0.9699307028171362 11 P04899 1 +Protein export 0.3466611635380899 0.3757044571996296 0.7071366238968881 1.0 0.9699307028171362 14 Q15070,P67812 2 +Pantothenate and coa biosynthesis 0.5686182078392461 0.3740375817342775 0.7083763559900433 1.0 0.9699307028171362 3 Q13057 1 +Pancreatic cancer 0.3368122581320711 0.3331429389140645 0.739026388243764 1.0 0.9842930119677714 14 P31751,P31749 2 +Pathways in cancer 0.2911135297669421 0.3229897254846273 0.746703023278201 1.0 0.9842930119677714 50 P31749,P56545,P14923,Q9NWH9,P31751,P40763,P36507,P42574,Q13043 9 +Inositol phosphate metabolism 0.3860387527088955 0.275379965524562 0.7830243344761738 1.0 0.9842930119677714 8 Q10713,Q01968 2 +Glioma 0.3214404210589434 0.2707745201651074 0.7865644579863058 1.0 0.9842930119677714 14 P31751,P31749 2 +Wnt signaling pathway 0.3051975047097397 0.2638294314265623 0.7919113548198675 1.0 0.9842930119677714 21 O75116,O43318,P56545,P19784,Q14738,Q08209,P17612 7 +Leukocyte transendothelial migration 0.3045108825853977 0.2627203366719072 0.792766140860373 1.0 0.9842930119677714 24 P35609,P04899 2 +Systemic lupus erythematosus 0.3299542705825228 0.2599802697994584 0.7948789928559536 1.0 0.9842930119677714 13 P05455,P62805,P35609,P62314,Q9P0M6 5 +Leishmania infection 0.3749302465028282 0.2433233371414652 0.8077549271376305 1.0 0.9842930119677714 8 O43318,Q15750 2 +Chronic myeloid leukemia 0.3055065529760201 0.2407283917230082 0.8097656325395601 1.0 0.9842930119677714 19 P56545,P31751,P31749 3 +Cytosolic dna sensing pathway 0.3915401301518306 0.2246087432898078 0.8222836625144234 1.0 0.9842930119677714 6 O15160,O14802,Q7Z434,Q9NZI8,O15111 5 +Viral myocarditis 0.3383163077000718 0.2183809234842085 0.827132327714371 1.0 0.9842930119677714 11 P78310 1 +Pentose and glucuronate interconversions 0.3912266459430287 0.2050299056404603 0.8375487600014468 1.0 0.9842930119677714 5 Q16851,O60701 2 +Purine metabolism 0.2708648487776127 0.1873939151875341 0.8513517930770629 1.0 0.9891674929077602 47 P19388 1 +Pyruvate metabolism 0.2735124809684945 0.1340238816187502 0.8933836899985355 1.0 0.9891674929077602 26 Q16822,Q04760 2 +Rig i like receptor signaling pathway 0.3241328738248221 0.122962777229593 0.902136573694332 1.0 0.9891674929077602 8 O43318 1 +Natural killer cell mediated cytotoxicity 0.2563793314943631 0.0730097376850236 0.9417983686408028 1.0 1.0 15 Q08209,P42574 2 +Proteasome 0.2466233015793224 0.0643090901225622 0.9487241155681914 1.0 1.0 36 P55036,O00487,P49721,P28072,P62333,Q14997 6 +Dorso ventral axis formation 0.2648121387283311 0.0163758678446712 0.9869345318386242 1.0 1.0 4 Q02750,P27361,P28482 3 +Vascular smooth muscle contraction 0.2192136784960277 0.008871950074434 0.9929213008740192 1.0 1.0 13 O75116,P62136,P36507,P17612,Q02750 5 diff --git a/msigdb_kegg/selections.json b/msigdb_kegg/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..9703ceffef5f465d708aad757f79ff09de1ccce5 --- /dev/null +++ b/msigdb_kegg/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Abc transporters", "Acute myeloid leukemia", "Adherens junction", "Adipocytokine signaling pathway", "Alanine aspartate and glutamate metabolism", "Aldosterone regulated sodium reabsorption", "Allograft rejection", "Alpha linolenic acid metabolism", "Alzheimers disease", "Amino sugar and nucleotide sugar metabolism", "Aminoacyl trna biosynthesis", "Amyotrophic lateral sclerosis als", "Antigen processing and presentation", "Apoptosis", "Arachidonic acid metabolism", "Arginine and proline metabolism", "Arrhythmogenic right ventricular cardiomyopathy arvc", "Ascorbate and aldarate metabolism", "Autoimmune thyroid disease", "Axon guidance", "B cell receptor signaling pathway", "Basal cell carcinoma", "Basal transcription factors", "Base excision repair", "Beta alanine metabolism", "Biosynthesis of unsaturated fatty acids", "Bladder cancer", "Butanoate metabolism", "Calcium signaling pathway", "Cardiac muscle contraction", "Cell adhesion molecules cams", "Cell cycle", "Chemokine signaling pathway", "Chronic myeloid leukemia", "Citrate cycle tca cycle", "Colorectal cancer", "Cysteine and methionine metabolism", "Cytokine cytokine receptor interaction", "Cytosolic dna sensing pathway", "Dilated cardiomyopathy", "Dna replication", "Dorso ventral axis formation", "Drug metabolism cytochrome p450", "Drug metabolism other enzymes", "Ecm receptor interaction", "Endocytosis", "Endometrial cancer", "Epithelial cell signaling in helicobacter pylori infection", "Erbb signaling pathway", "Ether lipid metabolism", "Fatty acid metabolism", "Fc epsilon ri signaling pathway", "Fc gamma r mediated phagocytosis", "Focal adhesion", "Folate biosynthesis", "Fructose and mannose metabolism", "Galactose metabolism", "Gap junction", "Glioma", "Glutathione metabolism", "Glycerolipid metabolism", "Glycerophospholipid metabolism", "Glycine serine and threonine metabolism", "Glycolysis gluconeogenesis", "Glycosaminoglycan biosynthesis chondroitin sulfate", "Glycosaminoglycan biosynthesis keratan sulfate", "Glycosaminoglycan degradation", "Glycosphingolipid biosynthesis ganglio series", "Glycosphingolipid biosynthesis globo series", "Glycosphingolipid biosynthesis lacto and neolacto series", "Glycosylphosphatidylinositol gpi anchor biosynthesis", "Glyoxylate and dicarboxylate metabolism", "Gnrh signaling pathway", "Graft versus host disease", "Hedgehog signaling pathway", "Hematopoietic cell lineage", "Histidine metabolism", "Homologous recombination", "Huntingtons disease", "Hypertrophic cardiomyopathy hcm", "Inositol phosphate metabolism", "Insulin signaling pathway", "Jak stat signaling pathway", "Leishmania infection", "Leukocyte transendothelial migration", "Limonene and pinene degradation", "Long term depression", "Long term potentiation", "Lysine degradation", "Lysosome", "Mapk signaling pathway", "Melanogenesis", "Melanoma", "Metabolism of xenobiotics by cytochrome p450", "Mismatch repair", "Mtor signaling pathway", "N glycan biosynthesis", "Natural killer cell mediated cytotoxicity", "Neurotrophin signaling pathway", "Nicotinate and nicotinamide metabolism", "Nitrogen metabolism", "Nod like receptor signaling pathway", "Non homologous end joining", "Non small cell lung cancer", "Notch signaling pathway", "Nucleotide excision repair", "O glycan biosynthesis", "Olfactory transduction", "One carbon pool by folate", "Oocyte meiosis", "Other glycan degradation", "Oxidative phosphorylation", "P53 signaling pathway", "Pancreatic cancer", "Pantothenate and coa biosynthesis", "Parkinsons disease", "Pathogenic escherichia coli infection", "Pathways in cancer", "Pentose and glucuronate interconversions", "Pentose phosphate pathway", "Peroxisome", "Phenylalanine metabolism", "Phosphatidylinositol signaling system", "Porphyrin and chlorophyll metabolism", "Ppar signaling pathway", "Primary bile acid biosynthesis", "Primary immunodeficiency", "Prion diseases", "Progesterone mediated oocyte maturation", "Propanoate metabolism", "Prostate cancer", "Proteasome", "Protein export", "Proximal tubule bicarbonate reclamation", "Purine metabolism", "Pyrimidine metabolism", "Pyruvate metabolism", "Regulation of actin cytoskeleton", "Regulation of autophagy", "Renal cell carcinoma", "Renin angiotensin system", "Retinol metabolism", "Riboflavin metabolism", "Ribosome", "Rig i like receptor signaling pathway", "Rna degradation", "Rna polymerase", "Selenoamino acid metabolism", "Small cell lung cancer", "Snare interactions in vesicular transport", "Sphingolipid metabolism", "Spliceosome", "Starch and sucrose metabolism", "Steroid biosynthesis", "Steroid hormone biosynthesis", "Sulfur metabolism", "Systemic lupus erythematosus", "T cell receptor signaling pathway", "Taste transduction", "Taurine and hypotaurine metabolism", "Terpenoid backbone biosynthesis", "Tgf beta signaling pathway", "Thyroid cancer", "Tight junction", "Toll like receptor signaling pathway", "Tryptophan metabolism", "Type i diabetes mellitus", "Type ii diabetes mellitus", "Tyrosine metabolism", "Ubiquitin mediated proteolysis", "Valine leucine and isoleucine biosynthesis", "Valine leucine and isoleucine degradation", "Vascular smooth muscle contraction", "Vasopressin regulated water reabsorption", "Vegf signaling pathway", "Vibrio cholerae infection", "Viral myocarditis", "Wnt signaling pathway"], "available_proteins": ["AARS", "AARS2", "AASDHPPT", "AASS", "ABCB1", "ABCB10", "ABCB7", "ABCC1", "ABCC4", "ABCD3", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACADM", "ACADSB", "ACADVL", "ACAP2", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO2", "ACOT7", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTN1", "ACTN2", "ACTN4", "ADA", "ADAR", "ADH5", "ADI1", "ADK", "ADO", "ADSL", "ADSS", "AFDN", "AGK", "AGL", "AGPAT1", "AGPS", "AHCY", "AHCYL1", "AIFM1", "AK1", "AK2", "AK4", "AKR1A1", "AKR1B1", "AKT1", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALYREF", "ANAPC5", "ANAPC7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP3B1", "AP3D1", "AP3M1", "APEX1", "APRT", "AQR", "ARFGAP1", "ARFGAP2", "ARHGAP5", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ASAH1", "ASNA1", "ASNS", "ATG3", "ATG4B", "ATIC", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATRX", "B4GAT1", "BAIAP2", "BAX", "BCAS2", "BCAT2", "BCL10", "BET1", "BIRC6", "BLVRA", "BLVRB", "BNIP1", "BPNT1", "BUB3", "BUD31", "CAB39", "CACYBP", "CAD", "CALD1", "CALR", "CANX", "CAPN1", "CARS", "CARS2", "CASK", "CASP3", "CASP6", "CBR1", "CCDC6", "CCNB1", "CD276", "CD47", "CD81", "CDC23", "CDC27", "CDC42", "CDC45", "CDC5L", "CDK1", "CDK2", "CDK4", "CDK6", "CDKN2A", "CDS2", "CFL1", "CFL2", "CHEK2", "CHERP", "CHKA", "CHMP2A", "CHMP5", "CHORDC1", "CHST14", "CHUK", "CKB", "CKMT1A*", "CLN5", "CLTA", "CLTC", "CMAS", "CMPK1", "CNOT1", "CNOT7", "CNOT9", "COASY", "COMT", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7C", "CPOX", "CPT2", "CRK", "CRKL", "CRNKL1", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CXADR", "CYB5R3", "CYC1", "CYFIP1", "CYP51A1", "DAD1", "DARS", "DARS2", "DAXX", "DCPS", "DCTN1", "DCTN2", "DCTN4", "DCXR", "DDB1", "DDOST", "DDX23", "DDX39B", "DDX3X", "DDX42", "DDX46", "DDX5", "DDX6", "DERL1", "DFFA", "DHCR24", "DHFR", "DHX15", "DHX16", "DHX8", "DIAPH1", "DIAPH3", "DIS3", "DLAT", "DLD", "DLST", "DNM1", "DNM1L", "DNM2", "DNMT1", "DPM1", "DPYSL2", "DSG2", "DSP", "DTYMK", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "EARS2", "EBP", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EFTUD2", "EHD1", "EHMT1", "EHMT2", "EI24", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "ELOB", "ELOC", "EMD", "ENDOD1", "ENO1", "ENOPH1", "EPB41", "EPB41L2", "EPB41L3", "EPHX1", "EPHX2", "EPRS", "ERCC2", "ERO1A", "EXO1", "EXOC4", "EXOC7", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FABP5", "FADS2", "FAH", "FAR1", "FARSA", "FARSB", "FASN", "FAU", "FDFT1", "FDPS", "FECH", "FEN1", "FH", "FLCN", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FUCA2", "G6PD", "GAA", "GABARAPL2", "GALK1", "GALM", "GALNT1", "GALNT2", "GANAB", "GAPDH", "GARS", "GART", "GBA", "GCAT", "GCDH", "GCLM", "GFPT1", "GGCT", "GGH", "GLA", "GLB1", "GLDC", "GLG1", "GLO1", "GLS", "GLUD1", "GM2A", "GMPPA", "GMPPB", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNE", "GNG12", "GNG5", "GNPDA1", "GNS", "GOT1", "GOT2", "GPAA1", "GPD2", "GPI", "GPT2", "GRB2", "GRHPR", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2E1", "GTF2I", "GUSB", "GYS1", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADH", "HADHA", "HADHB", "HCCS", "HDAC1", "HDAC2", "HERC2", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HMGB1", "HMGCL", "HMGCS1", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA3", "HNRNPC", "HNRNPK", "HNRNPM", "HNRNPU", "HPRT1", "HSD17B10", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HUWE1", "IARS", "IARS2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IGF1R", "IGF2BP1", "IGF2R", "IMPDH2", "IQGAP1", "IRS4", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPK1", "IVD", "JUP", "KARS", "KDELR1", "KDSR", "L2HGDH", "LAMP1", "LAP3", "LARS", "LARS2", "LCLAT1", "LDHA", "LDHB", "LIG1", "LIG3", "LIPA", "LLGL1", "LMNA", "LNPEP", "LPCAT1", "LPGAT1", "LSM2", "LSM6", "LSS", "LTA4H", "LYPLA1", "M6PR", "MAP2K1", "MAP2K2", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MARCKS", "MARCKSL1", "MARS", "MAT2A", "MAT2B", "MAVS", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MDH1", "MDH2", "ME1", "ME2", "MGST2", "MGST3", "MID1", "MIF", "MMAB", "MOGS", "MPG", "MPHOSPH6", "MPI", "MPST", "MRE11", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTAP", "MTCH1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR6", "MTOR", "MUT", "MVD", "MVK", "MYH10", "MYH9", "MYL6", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NARS", "NBN", "NCBP1", "NCK1", "NCKAP1", "NCL", "NCSTN", "NDUFA10", "NDUFA11", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NEDD4", "NEFL", "NEFM", "NLN", "NLRX1", "NME1", "NME2", "NNT", "NPC1", "NSD2", "NSDHL", "NSF", "NT5C2", "NT5C3A", "NUDT12", "NUDT5", "OAT", "OCRL", "OGDH", "ORC3", "OXA1L", "P4HA1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAK2", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PC", "PCBP1", "PCCA", "PCCB", "PCK2", "PCNA", "PDCD6", "PDCD6IP", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PECR", "PEX14", "PEX19", "PEX5", "PFAS", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PHF5A", "PHGDH", "PIGK", "PIGS", "PIGU", "PIK3C2A", "PIN1", "PISD", "PKM", "PKMYT1", "PLA2G15", "PLCG1", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PMPCA", "PMVK", "PNP", "PNPT1", "POLA1", "POLA2", "POLD1", "POLDIP2", "POLE", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "PPA1", "PPA2", "PPAT", "PPID", "PPIH", "PPIL1", "PPOX", "PPP1CA", "PPP1CB", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP5C", "PPT1", "PPT2", "PQBP1", "PRDX5", "PRDX6", "PRIM1", "PRIM2", "PRKAA1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF6", "PRPF8", "PSAP", "PSAT1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PTDSS1", "PTGES2", "PTPN1", "PTPN11", "PUF60", "PXN", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "RAB13", "RAB3B", "RAB5A", "RAB5B", "RAB5C", "RAC1", "RAD21", "RAD23B", "RAD50", "RAPGEF2", "RARS", "RASA1", "RBM17", "RBM25", "RBM8A", "RBMX", "RDH11", "RDX", "RETSAT", "REXO2", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHOA", "RNASEH2A", "RNASEH2B", "ROCK2", "RPA1", "RPA2", "RPA3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRM1", "RRM2", "RUFY1", "RUVBL1", "SAE1", "SARS", "SARS2", "SART1", "SC5D", "SCARB2", "SCD", "SCP2", "SDHA", "SDHB", "SEC11A", "SEC22B", "SEC61A1", "SEC61B", "SEC63", "SETD7", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SGPL1", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHMT1", "SHMT2", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC19A1", "SLC25A10", "SLC25A15", "SLC25A17", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLK", "SLTM", "SMC1A", "SMC3", "SMNDC1", "SMPD4", "SMS", "SNAP23", "SNAP29", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SOAT1", "SOD2", "SORD", "SPCS2", "SPCS3", "SPR", "SPTAN1", "SPTLC1", "SPTLC2", "SQLE", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPRA", "SRPRB", "SRSF1", "SRSF10", "SRSF3", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "STAG2", "STAM", "STAMBP", "STAT1", "STAT3", "STIP1", "STK4", "STMN1", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX17", "STX18", "STX4", "STX5", "STX7", "STX8", "SUCLA2", "SUCLG1", "SUCLG2", "SUGT1", "SV2A", "SYMPK", "TAB1", "TALDO1", "TARS", "TARS2", "TCERG1", "TECR", "TFAM", "TFG", "TFRC", "THOC1", "THOC3", "THOP1", "TJP1", "TK1", "TKT", "TLN1", "TOMM40", "TP53", "TPI1", "TPM3", "TPM4", "TPP1", "TPR", "TRA2A", "TRA2B", "TRIM21", "TRIM25", "TRIP12", "TRMT11", "TROVE2", "TSC2", "TSG101", "TSTA3", "TTC37", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TXNDC12", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3C", "UBE4A", "UBR5", "UCK2", "UGDH", "UGP2", "UMPS", "UNC45A", "UNG", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USP39", "VAMP7", "VAPA", "VARS1", "VARS2", "VCL", "VDAC1", "VDAC2", "VDAC3", "VPS4A", "WARS", "WBP11", "WDR61", "XAB2", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YKT6", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZFYVE16", "ZYX"], "leading_proteins": ["ABCB7", "ABCC1", "ACOX1", "ACOX3", "ACTN2", "AKT1", "AKT2", "AP2A2", "ARHGDIA", "ATG4B", "ATP5B", "ATP5C1", "ATP5H", "ATP5I", "ATP6", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "BAIAP2", "CAPN1", "CASP3", "CCNB1", "CDKN2A", "CDS2", "CHKA", "CHORDC1", "CHUK", "CMPK1", "COASY", "COX4I1", "COX6C", "COX7C", "CPT2", "CSNK2A2", "CTBP2", "CTPS2", "CXADR", "DAXX", "DCTN4", "DERL1", "DPM1", "DYNC1H1", "DYNC1LI2", "ENDOD1", "EXOC4", "F11R", "FABP5", "FAU", "GAPDH", "GLO1", "GNAI2", "GNG5", "H2AFY2", "H4C1*", "HMOX1", "HMOX2", "HSPB1", "IDE", "IGF2BP1", "JUP", "LIG1", "MAP2K1", "MAP2K2", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MAVS", "NAMPT", "NCSTN", "NDUFA11", "NDUFA5", "NDUFA8", "NDUFA9", "NDUFB3", "NDUFS2", "NDUFS3", "NDUFS7", "NEFL", "NEFM", "NT5C3A", "NUDT12", "OCRL", "OXA1L", "PAFAH1B3", "PCK2", "PLA2G15", "PMPCA", "POLA2", "POLE", "POLR1A", "POLR1B", "POLR1C", "POLR2E", "POLR3A", "PPP1CA", "PPP2R5D", "PPP3CA", "PRKACA", "PRKAR1A", "PSMB2", "PSMB6", "PSMC6", "PSMD14", "PSMD4", "PSME4", "RAB5A", "RASA1", "REXO2", "ROCK2", "RPA3", "RPL10A", "RPL12", "RPL13", "RPL22", "RPL23", "RPL23A", "RPL26", "RPL27", "RPL28", "RPL29", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL38", "RPL7", "RPL7A", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPS13", "RPS15", "RPS15A", "RPS16", "RPS18", "RPS19", "RPS2", "RPS3A", "RPS6", "RPS7", "RPS8", "RPS9", "RPSA", "SEC11A", "SIN3A", "SLC25A5", "SLTM", "SNRPD1", "SOD2", "SSB", "SSBP1", "STAM", "STAT3", "STK4", "STT3A", "STT3B", "TAB1", "TJP1", "TUBB2A", "TUBB4A", "TUBB4B", "TXNRD1", "UCK2", "UGDH", "UGP2", "UNG", "UQCR10", "UQCRB", "UQCRQ"]} \ No newline at end of file diff --git a/msigdb_reactome/advanced/idx2term.json b/msigdb_reactome/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9eb37a34938634f5540318f5a88d99d5335a4a6d --- /dev/null +++ b/msigdb_reactome/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial protein import", "1": "Protein localization", "2": "Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins", "3": "Respiratory electron transport", "4": "Complex i biogenesis", "5": "Cellular response to starvation", "6": "Metabolism of vitamins and cofactors", "7": "Mitochondrial biogenesis", "8": "Cdc42 gtpase cycle", "9": "Response of eif2ak4 gcn2 to amino acid deficiency"} \ No newline at end of file diff --git a/msigdb_reactome/advanced/plot_0.png b/msigdb_reactome/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..226c236ec305d5228c6e998f927d23fb1e31c5c1 --- /dev/null +++ b/msigdb_reactome/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5a8ee26ef8d2cba59745e543d646be219669711e83f1750b08c83b209abeabe0 +size 202694 diff --git a/msigdb_reactome/advanced/plot_1.png b/msigdb_reactome/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..d7ebf9480bd7c97622e06ff80096489efeee3391 --- /dev/null +++ b/msigdb_reactome/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:71f61f66186a649fba039b439f9dbaa2ea9776b8d2a8e6f346f3b7c7aa494250 +size 205194 diff --git a/msigdb_reactome/advanced/plot_2.png b/msigdb_reactome/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..74177f5624314029c3e9205107a913861a7d6844 --- /dev/null +++ b/msigdb_reactome/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:27353d4f9358eb178cd535bdce0356b31bb86761ad98f388b2185276b643d8ec +size 212802 diff --git a/msigdb_reactome/advanced/plot_3.png b/msigdb_reactome/advanced/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..c1669927c8dc4a7fbd15728d8a5047d6e9ac3ffb --- /dev/null +++ b/msigdb_reactome/advanced/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e679c0c81318a2d95003f64b321e00d32b5c0092e58c3577fba29dda71e2c0e2 +size 206347 diff --git a/msigdb_reactome/advanced/plot_4.png b/msigdb_reactome/advanced/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..c569f004a2201b4259d23c254574581ce25224a1 --- /dev/null +++ b/msigdb_reactome/advanced/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9ba9e5665513361e269fa97e5864b5fa96c68212e78e52f6b8b48f4eaabf91fd +size 196875 diff --git a/msigdb_reactome/advanced/plot_5.png b/msigdb_reactome/advanced/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..2092ad205c201efc64e0fd9047c364b6ee9b1560 --- /dev/null +++ b/msigdb_reactome/advanced/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ccf051210cd04f6d690e34648bb180692d73389e736b40bb1e9f4beb70b23abe +size 203416 diff --git a/msigdb_reactome/advanced/plot_6.png b/msigdb_reactome/advanced/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..8c0e0e342ccd746f6edd8b753c9e0e99897d3e01 --- /dev/null +++ b/msigdb_reactome/advanced/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b4f500f695112d125387fd152a2ddd76a51d7b1f118b914cef89110788b66f59 +size 208894 diff --git a/msigdb_reactome/advanced/plot_7.png b/msigdb_reactome/advanced/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..fbd07db4d3f3c289be601ce9babb54b3473c6f85 --- /dev/null +++ b/msigdb_reactome/advanced/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5fc44083b47f74292bed581628881997ee4b9fdebc1f8bb2b65440f002359e05 +size 204979 diff --git a/msigdb_reactome/advanced/plot_8.png b/msigdb_reactome/advanced/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..d654bd39d4097d38f37e518f91f4333b65a83f49 --- /dev/null +++ b/msigdb_reactome/advanced/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6013ee2008a2b4077c726168e55125ae464864ee2ffa323f16c51985f6763e0f +size 203267 diff --git a/msigdb_reactome/advanced/plot_9.png b/msigdb_reactome/advanced/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..d7bfca2a180ef5e1e139f57483aba30de19bb837 --- /dev/null +++ b/msigdb_reactome/advanced/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:dc04a35d0080fd68b5290b6a626935dba23a70f5a4c2b7fbf2db1c6739bba39a +size 202568 diff --git a/msigdb_reactome/basic/idx2term.json b/msigdb_reactome/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..342d10ea5ccccd98d88815bd95fff75678f122c8 --- /dev/null +++ b/msigdb_reactome/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial protein import", "1": "Protein localization", "2": "Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins", "3": "Respiratory electron transport", "4": "Complex i biogenesis", "5": "Cellular response to starvation", "6": "Metabolism of vitamins and cofactors", "7": "Mitochondrial biogenesis", "8": "Cdc42 gtpase cycle", "9": "Response of eif2ak4 gcn2 to amino acid deficiency", "10": "Eukaryotic translation elongation", "11": "Rac2 gtpase cycle", "12": "Translocation of slc2a4 glut4 to the plasma membrane", "13": "Selenoamino acid metabolism", "14": "Signaling by vegf", "15": "B wich complex positively regulates rrna expression", "16": "Rho gtpase cycle", "17": "Eukaryotic translation initiation", "18": "Mtor signalling", "19": "Srp dependent cotranslational protein targeting to membrane", "20": "Esr mediated signaling", "21": "Metabolism of water soluble vitamins and cofactors", "22": "Positive epigenetic regulation of rrna expression", "23": "Nonsense mediated decay nmd", "24": "Rna polymerase i transcription", "25": "Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s", "26": "Rac3 gtpase cycle", "27": "Cell death signalling via nrage nrif and nade", "28": "Rna polymerase i promoter escape", "29": "Leishmania infection", "30": "Transcriptional regulation by runx2", "31": "Runx1 regulates transcription of genes involved in differentiation of hscs", "32": "Rna polymerase i transcription initiation", "33": "Rac1 gtpase cycle", "34": "The citric acid tca cycle and respiratory electron transport", "35": "Signaling by nuclear receptors", "36": "Abc family proteins mediated transport", "37": "Transport of small molecules", "38": "Signaling by rho gtpases miro gtpases and rhobtb3", "39": "Cellular response to chemical stress", "40": "Negative epigenetic regulation of rrna expression", "41": "Developmental biology", "42": "Sensory perception", "43": "Autophagy", "44": "Cytoprotection by hmox1", "45": "Tp53 regulates metabolic genes", "46": "Resolution of sister chromatid cohesion", "47": "Epigenetic regulation of gene expression", "48": "Infectious disease", "49": "Transcriptional regulation by mecp2"} \ No newline at end of file diff --git a/msigdb_reactome/basic/plot_0.png b/msigdb_reactome/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..a0a9a3191176790eae5cba73c7f0835318566937 --- /dev/null +++ b/msigdb_reactome/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:43ab9b5d9e106c2fb54908488fef2d043e0f4f6be9552d055bbc4168819dda4e +size 138616 diff --git a/msigdb_reactome/basic/plot_1.png b/msigdb_reactome/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..96e7a85124858f60ea9170f1062809b63b9460fa --- /dev/null +++ b/msigdb_reactome/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2f75c72efcda0d624d177b36fe26e4664c1768a6ecc4412c88a4196726f22c12 +size 132061 diff --git a/msigdb_reactome/basic/plot_10.png b/msigdb_reactome/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..b7ffa5aa3e82b513f4a151e4439fdb21e0597d53 --- /dev/null +++ b/msigdb_reactome/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d1d8d8d2f967631d1b6a9510e04b74362e97ccd71f3d6dbf30d508da0f24ebc0 +size 142048 diff --git a/msigdb_reactome/basic/plot_11.png b/msigdb_reactome/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..5211bdefae4b965bbefb9d7a7853b8e12eb9e864 --- /dev/null +++ b/msigdb_reactome/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e0cf0b8d98460f1070492f843cc68fbe58c0f66e350cf5fbbffcec6a5259be6d +size 131618 diff --git a/msigdb_reactome/basic/plot_12.png b/msigdb_reactome/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..57c09f2d7ee4a50c19299d7d6d67a28d6e2eb012 --- /dev/null +++ b/msigdb_reactome/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d0b605eb15a74a2ce58e3e71e4238767f70f7a6b4fcc07af4819f8f382b6e2c8 +size 146856 diff --git a/msigdb_reactome/basic/plot_13.png b/msigdb_reactome/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..8937ed8d764766ae5095c8fabd4bcae82658ea94 --- /dev/null +++ b/msigdb_reactome/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8df3e9ed52af38241a02c89983969364165f629e437ffe90944de9dab316a6fb +size 139794 diff --git a/msigdb_reactome/basic/plot_14.png b/msigdb_reactome/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..d7f52a1ba207e68fd40ba4d0a95ce8e953d65d90 --- /dev/null +++ b/msigdb_reactome/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:30172ee6ede4182325119233e38b08a526acb2a5c3ce9d11d7b5ff2ca35c8275 +size 133471 diff --git a/msigdb_reactome/basic/plot_15.png b/msigdb_reactome/basic/plot_15.png new file mode 100644 index 0000000000000000000000000000000000000000..0cf9f8fbfda5a036b5ccb1cf7c4a12b6e191b210 --- /dev/null +++ b/msigdb_reactome/basic/plot_15.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0c897e2ecbb348a5e691628b254bb17de1b25af5c8088d48b3b0abf0f231fab9 +size 143444 diff --git a/msigdb_reactome/basic/plot_16.png b/msigdb_reactome/basic/plot_16.png new file mode 100644 index 0000000000000000000000000000000000000000..c86cbdd014af669fea152859e74e5f6c149497ec --- /dev/null +++ b/msigdb_reactome/basic/plot_16.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:67e87c61ffea1f44a29ea3aee941d57e806296e5dab48ce0da10dd7bd6bfaec1 +size 136258 diff --git a/msigdb_reactome/basic/plot_17.png b/msigdb_reactome/basic/plot_17.png new file mode 100644 index 0000000000000000000000000000000000000000..867f02da3931fce335fe8626f44cb1ff5c929b17 --- /dev/null +++ b/msigdb_reactome/basic/plot_17.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:42ac3a38c1d53044ba4d412c879baf408de2fab3fde7fb441a3a426843d8cd61 +size 142656 diff --git a/msigdb_reactome/basic/plot_18.png b/msigdb_reactome/basic/plot_18.png new file mode 100644 index 0000000000000000000000000000000000000000..b41dd27e6ea9ac20bd7dfee24c0bb4ef9190b47c --- /dev/null +++ b/msigdb_reactome/basic/plot_18.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0ac48fb9f960cf02d6c636aaeafbbe3523aa15bd49f38c94990fc8c686155cee +size 130700 diff --git a/msigdb_reactome/basic/plot_19.png b/msigdb_reactome/basic/plot_19.png new file mode 100644 index 0000000000000000000000000000000000000000..1c94b4943376230308830fb7d89fd891b57e4285 --- /dev/null +++ b/msigdb_reactome/basic/plot_19.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a15e08907cf98b54560bb59057fbd576498241533e663a16bab4b628f8b9929e +size 149293 diff --git a/msigdb_reactome/basic/plot_2.png b/msigdb_reactome/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..3e075cc7315f342e7e7d0c442b83bff9ca4175f6 --- /dev/null +++ b/msigdb_reactome/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:419bd5e7b1ed8d931b822dbd2d8b3b30a7ba1557ddee040418347cb088af9ad9 +size 150865 diff --git a/msigdb_reactome/basic/plot_20.png b/msigdb_reactome/basic/plot_20.png new file mode 100644 index 0000000000000000000000000000000000000000..ff71845fc6fad2111e8b2d51312406f3d2a7a5aa --- /dev/null +++ b/msigdb_reactome/basic/plot_20.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:17a3eaff70147cb30113002fe4c251cd56e0c379c758c7e5d34c5c4299c46bc1 +size 126334 diff --git a/msigdb_reactome/basic/plot_21.png b/msigdb_reactome/basic/plot_21.png new file mode 100644 index 0000000000000000000000000000000000000000..fe15e45cc8143b1f3eecb01f403a965b9490b0e1 --- /dev/null +++ b/msigdb_reactome/basic/plot_21.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:540a30c4dca33ff431c51a384925f641400bb2477111c1ca6f96b9611ab8e17d +size 141354 diff --git a/msigdb_reactome/basic/plot_22.png b/msigdb_reactome/basic/plot_22.png new file mode 100644 index 0000000000000000000000000000000000000000..2f195dc44c547f1df63d6cb6a0e2701c4885b4e1 --- /dev/null +++ b/msigdb_reactome/basic/plot_22.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:61adaf452364990e25949833a4d6d13003f492525f7bdfab92808bef80a27086 +size 138875 diff --git a/msigdb_reactome/basic/plot_23.png b/msigdb_reactome/basic/plot_23.png new file mode 100644 index 0000000000000000000000000000000000000000..3d3eeb498ac3d70408bcd2fd5020ebb409d32705 --- /dev/null +++ b/msigdb_reactome/basic/plot_23.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:20652d3d8e2ddaaf7e10e038d939f6130123d4f6ed6cd6bdd5421aad9a95ff2a +size 144434 diff --git a/msigdb_reactome/basic/plot_24.png b/msigdb_reactome/basic/plot_24.png new file mode 100644 index 0000000000000000000000000000000000000000..f88d100212979c2306edad6670c2931bffd5ad9a --- /dev/null +++ b/msigdb_reactome/basic/plot_24.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e3d1a93904de1f2694369a4d7a436e329199bc91813cb121f264920f14dd61ec +size 143032 diff --git a/msigdb_reactome/basic/plot_25.png b/msigdb_reactome/basic/plot_25.png new file mode 100644 index 0000000000000000000000000000000000000000..27e8dd748ed4b358e2a686030fb98094dd57a55e --- /dev/null +++ b/msigdb_reactome/basic/plot_25.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:598b045574af8834d1a53f5d7760904be2dd9ded3f20e96525740c3cdbc18f99 +size 146559 diff --git a/msigdb_reactome/basic/plot_26.png b/msigdb_reactome/basic/plot_26.png new file mode 100644 index 0000000000000000000000000000000000000000..bfde62270106b4485c7031300fa3d970b6ae76b0 --- /dev/null +++ b/msigdb_reactome/basic/plot_26.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:38e137eafc987ce59d7e3d1a4620bb4ad1d5aa75b986e8ded509f1e3eadcb4b6 +size 139041 diff --git a/msigdb_reactome/basic/plot_27.png b/msigdb_reactome/basic/plot_27.png new file mode 100644 index 0000000000000000000000000000000000000000..5efe374196d7941898aa6b24f50c7750c589f3b9 --- /dev/null +++ b/msigdb_reactome/basic/plot_27.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5878f68eb3425d49331373da22ed08f9dbc48e90978429b9c8fb2a81141f85b4 +size 137051 diff --git a/msigdb_reactome/basic/plot_28.png b/msigdb_reactome/basic/plot_28.png new file mode 100644 index 0000000000000000000000000000000000000000..939cd993ace433923cc8ee53bd6533b7dc9e7f44 --- /dev/null +++ b/msigdb_reactome/basic/plot_28.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5fce153cb5edecf7df5c1ae6f9f26bdf2a73f99f6d12ae92d5ec21f8699b367b +size 137884 diff --git a/msigdb_reactome/basic/plot_29.png b/msigdb_reactome/basic/plot_29.png new file mode 100644 index 0000000000000000000000000000000000000000..d7d1a2589a782f3f5fca753d3f19e3823c1efe02 --- /dev/null +++ b/msigdb_reactome/basic/plot_29.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:40dfc99204851bd24c2993742a001243b6d951445ff153ec59036ffce28e870b +size 133735 diff --git a/msigdb_reactome/basic/plot_3.png b/msigdb_reactome/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..d18ac19771c1397da79b2df5d15804d490d1b1a7 --- /dev/null +++ b/msigdb_reactome/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7f0b750fe7de0a541390fa4ddfc1cb61aceb3cefcb50099989f8985a38b95fcf +size 139292 diff --git a/msigdb_reactome/basic/plot_30.png b/msigdb_reactome/basic/plot_30.png new file mode 100644 index 0000000000000000000000000000000000000000..1bff4ccc7d68d23ad3ee29086da307b91b82d57d --- /dev/null +++ b/msigdb_reactome/basic/plot_30.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:cb6ebe23c0709a1e8026eca1da96a9dd5b99c9aa049e5312f946c2082f615bce +size 143157 diff --git a/msigdb_reactome/basic/plot_31.png b/msigdb_reactome/basic/plot_31.png new file mode 100644 index 0000000000000000000000000000000000000000..f2ab0cd224d2b842fd1f2d440d5bb80cd0089fbe --- /dev/null +++ b/msigdb_reactome/basic/plot_31.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:69ee31c84319c1b426c1c5c71559ffb443f85fb740ef10708f70ea6085e0d6df +size 146850 diff --git a/msigdb_reactome/basic/plot_32.png b/msigdb_reactome/basic/plot_32.png new file mode 100644 index 0000000000000000000000000000000000000000..c593c88e022a8c98f95f991756b8d4e6acfb3282 --- /dev/null +++ b/msigdb_reactome/basic/plot_32.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:299b44da8d6388253637b48fb575ed43791a4a12973c6689bced9071b7d51045 +size 141318 diff --git a/msigdb_reactome/basic/plot_33.png b/msigdb_reactome/basic/plot_33.png new file mode 100644 index 0000000000000000000000000000000000000000..4a8181b131e552bf4dc9feca1d31f939d73b21c9 --- /dev/null +++ b/msigdb_reactome/basic/plot_33.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4049b80eae3fb4db1cb8d7787eaf61acd2b9aa3bcb68ad82cf84935d139798fc +size 136055 diff --git a/msigdb_reactome/basic/plot_34.png b/msigdb_reactome/basic/plot_34.png new file mode 100644 index 0000000000000000000000000000000000000000..344176ee86fe4634cc13e509057c6ad797d29665 --- /dev/null +++ b/msigdb_reactome/basic/plot_34.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f2e4385ad98b0ce29f41b87572141a1ee412610cb21d83803d5700ae7b8a4786 +size 146859 diff --git a/msigdb_reactome/basic/plot_35.png b/msigdb_reactome/basic/plot_35.png new file mode 100644 index 0000000000000000000000000000000000000000..8484e566798765421d27c4d322248d6304534701 --- /dev/null +++ b/msigdb_reactome/basic/plot_35.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:cbb3e4f6907f3ab34672c4fefc7fc71e74f51cc5bb8d0fc976fd1818c332d253 +size 148311 diff --git a/msigdb_reactome/basic/plot_36.png b/msigdb_reactome/basic/plot_36.png new file mode 100644 index 0000000000000000000000000000000000000000..44f1ab7309780bbf2e1d9b5527e539bc7c8469a9 --- /dev/null +++ b/msigdb_reactome/basic/plot_36.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:acf81894e3afad45dfff1cbd01f2cab5a4dd2846d12ee569b85a4535a4881d3e +size 142190 diff --git a/msigdb_reactome/basic/plot_37.png b/msigdb_reactome/basic/plot_37.png new file mode 100644 index 0000000000000000000000000000000000000000..7cbd48046b9eea3ca6a9d7d56e10c817824a368f --- /dev/null +++ b/msigdb_reactome/basic/plot_37.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1704b205365669dec8e1155cadb42ee05d93b14d57904ff6d57fb823c111872c +size 144128 diff --git a/msigdb_reactome/basic/plot_38.png b/msigdb_reactome/basic/plot_38.png new file mode 100644 index 0000000000000000000000000000000000000000..0d12a023783ad13339259d1cf6a5eb678a2ce952 --- /dev/null +++ b/msigdb_reactome/basic/plot_38.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:29d4c003a8ee3aa8acfb80c3484121e517a7fe86ed68fdd60daa2c1da51bbb67 +size 144727 diff --git a/msigdb_reactome/basic/plot_39.png b/msigdb_reactome/basic/plot_39.png new file mode 100644 index 0000000000000000000000000000000000000000..53a67b2ad666ca5681cb936fec89443e134991ec --- /dev/null +++ b/msigdb_reactome/basic/plot_39.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3bfcdf14b8da0ec98251d8012c064707f795e1252e87ee23d6a37217ee9d601b +size 146555 diff --git a/msigdb_reactome/basic/plot_4.png b/msigdb_reactome/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..d0ae09baad2eee709048458cac94ae713e814877 --- /dev/null +++ b/msigdb_reactome/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:15c09c609e1a89691008970647874931dd0bc48d9c61a4bde61f5f89fee82b42 +size 137268 diff --git a/msigdb_reactome/basic/plot_40.png b/msigdb_reactome/basic/plot_40.png new file mode 100644 index 0000000000000000000000000000000000000000..79a8cc31b76e3da3500163a3e4994b7f1d5332c7 --- /dev/null +++ b/msigdb_reactome/basic/plot_40.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ecd7a80ceb47942222f6ad8a90898966647ecff3758d21d2d798ee53028b2c5f +size 141154 diff --git a/msigdb_reactome/basic/plot_41.png b/msigdb_reactome/basic/plot_41.png new file mode 100644 index 0000000000000000000000000000000000000000..ce4ca3984ac9f6d5cc60814e87f432c551f23208 --- /dev/null +++ b/msigdb_reactome/basic/plot_41.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:41efc3a0aceac5b2b2cfded3c346166fd72d053e980efd9d8a3c466f0ccd25f4 +size 140916 diff --git a/msigdb_reactome/basic/plot_42.png b/msigdb_reactome/basic/plot_42.png new file mode 100644 index 0000000000000000000000000000000000000000..05d567489b8e7faaa7cb14a70c2db9ff2c396931 --- /dev/null +++ b/msigdb_reactome/basic/plot_42.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:516ec089a88d91cb57d790176401a42ddadeafa7d8813923b027b541047ec26f +size 135485 diff --git a/msigdb_reactome/basic/plot_43.png b/msigdb_reactome/basic/plot_43.png new file mode 100644 index 0000000000000000000000000000000000000000..29e213ffc629b3ac8e6b2f36a8635ecc05ff4cc1 --- /dev/null +++ b/msigdb_reactome/basic/plot_43.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0c3fa86dbc92c8fe1fe30d3c4cb27c3547d8b350de031e88262e765759f812c9 +size 138900 diff --git a/msigdb_reactome/basic/plot_44.png b/msigdb_reactome/basic/plot_44.png new file mode 100644 index 0000000000000000000000000000000000000000..243d3755d997f9b262ec7a72b2d7295d680fad32 --- /dev/null +++ b/msigdb_reactome/basic/plot_44.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9c70de22fb2020867cdd6d9061f4ee128b7671d37dc3f55d797db448cb5ac598 +size 143801 diff --git a/msigdb_reactome/basic/plot_45.png b/msigdb_reactome/basic/plot_45.png new file mode 100644 index 0000000000000000000000000000000000000000..63d4a559d305a71152c722f90f78bd9581baa83f --- /dev/null +++ b/msigdb_reactome/basic/plot_45.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:81a11e05fccd11b6a392dbf0013d1f72205821359e1f9f40ad854431bd8a7a78 +size 148351 diff --git a/msigdb_reactome/basic/plot_46.png b/msigdb_reactome/basic/plot_46.png new file mode 100644 index 0000000000000000000000000000000000000000..01a8fc66dfd52236fe98aebd6c8bc0913e9ff323 --- /dev/null +++ b/msigdb_reactome/basic/plot_46.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2708befcddad4fda999deeae24c6cc486edf6ef3815d23a13b926cdc9a1c1066 +size 152822 diff --git a/msigdb_reactome/basic/plot_47.png b/msigdb_reactome/basic/plot_47.png new file mode 100644 index 0000000000000000000000000000000000000000..4ae3f738ba0a713f9b42cf8cbf180f092caa2d81 --- /dev/null +++ b/msigdb_reactome/basic/plot_47.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7f6557b5e329fcbb72ca559b637db73e58b147b771dd283f67a0c7ed5bc03d93 +size 149026 diff --git a/msigdb_reactome/basic/plot_48.png b/msigdb_reactome/basic/plot_48.png new file mode 100644 index 0000000000000000000000000000000000000000..61e51df6eee4211b7604a767bb2fa40b77b6dea5 --- /dev/null +++ b/msigdb_reactome/basic/plot_48.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:75d41d2530901f16666eb38c3d6fa2bbb141cf9c2b0288ecb93953c3db1f6c06 +size 138882 diff --git a/msigdb_reactome/basic/plot_49.png b/msigdb_reactome/basic/plot_49.png new file mode 100644 index 0000000000000000000000000000000000000000..d792f3003c20fdd63772be15326e78234e1f846a --- /dev/null +++ b/msigdb_reactome/basic/plot_49.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0a1ca6b643cc152d737dfa9d1101898f794085b6f5c1cee993606bada03289d6 +size 140713 diff --git a/msigdb_reactome/basic/plot_5.png b/msigdb_reactome/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..683f448228c3443de6c3e55a069e87c847940f70 --- /dev/null +++ b/msigdb_reactome/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a879a0acf5249796596976a72c161fd3e6889fa0c970642c4d4422438ea21943 +size 147432 diff --git a/msigdb_reactome/basic/plot_6.png b/msigdb_reactome/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..99cfa7f5aa6986607b88d4acb7eec4bc0cc677c0 --- /dev/null +++ b/msigdb_reactome/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2297d640e943699c9ccc05351874dbcb87c0e837d47b355689058c76974fd5a3 +size 141521 diff --git a/msigdb_reactome/basic/plot_7.png b/msigdb_reactome/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..130eab220affc4877661b1c670376202d88cd94b --- /dev/null +++ b/msigdb_reactome/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9d7f5baedfcef223207b36a9f7b949f5b43c481cff05d3d79048f40b05c481c2 +size 134208 diff --git a/msigdb_reactome/basic/plot_8.png b/msigdb_reactome/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..ed1351970027ff684520c95c43db61c98a859896 --- /dev/null +++ b/msigdb_reactome/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:88c67a3e27a03255ebd44030ca3166ba4aaac626f7cba9e47a8a967219a3566e +size 135368 diff --git a/msigdb_reactome/basic/plot_9.png b/msigdb_reactome/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..992deeb5587343e839b773bda20c1d04e7cd5571 --- /dev/null +++ b/msigdb_reactome/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:71479612226d360ad1232b9d9f1094fd02f7a476a8bcfe4fc4e309faa8b35b26 +size 147872 diff --git a/msigdb_reactome/consensus.joblib b/msigdb_reactome/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..b038436971e825ae69cdf5c51b6d2f180d37ca91 --- /dev/null +++ b/msigdb_reactome/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:25d9f5734e25aa1b521e55bb04b1e30cba8bcc6ebaee1666f207c9b160e4f218 +size 143676 diff --git a/msigdb_reactome/df_merge.tsv b/msigdb_reactome/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..8036d7237b8ce2e811cd493650dddca4243b8a9a --- /dev/null +++ b/msigdb_reactome/df_merge.tsv @@ -0,0 +1,20 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Mitochondrial protein import 6 35 3.6660050550561536 0.0002463690566252 13.468446601941748 34.5873786407767 1.6025718162972953 0.1874419874946837 6.078090089851624 2.2108812815475147 1.8878681708577505 0.2901223460226844 0.0057865829735411 0.0001627366612638 0.0020931499805748 0.0004411141019179 0.0065574427418938 +Protein localization 12 67 2.8418745681614306 0.0044849133053612 25.97087378640777 74.18203883495146 1.5594110758345356 0.2555609300308859 10.717199959161563 6.26233677332747 2.0947329132902324 0.3569924888492793 0.013927030207542 0.0043644807500144 0.0420318576165777 0.0019029575232507 0.0077394766003062 +Cristae formation 1 20 2.8253763661095515 0.0047225108874584 8.475728155339805 19.805825242718445 0.8613288847471563 0.2756396593916832 3.7825471979528897 1.2052333490949263 1.5890526548766304 0.3070386069824295 0.002648097293 0.0070670490819082 0.0254170330798906 0.0248436194903882 0.0374891712618371 +Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 24 58 2.6237944614910385 0.0086956242940525 20.8373786407767 62.38106796116505 0.8350130317954786 0.3584533980641267 8.974357262450994 5.887120286458052 1.9056004199022172 0.3784220720284639 1.0 0.4233408288956517 0.0916006222813593 0.0016342594482038 0.0001169218317504 +Cargo trafficking to the periciliary membrane 2 20 2.5623199692167944 0.0103975477868452 4.793689320388349 19.611650485436893 0.4417439518734258 0.5335628156487865 3.7330404824062655 2.13833711687666 0.905912611492572 0.3248932005652495 1.0 0.1839914155878272 0.0071738165736661 0.0799458311672583 0.1471696269103632 +Organelle biogenesis and maintenance 4 83 2.5250282097939656 0.0115689002303229 25.364077669902912 93.59466019417476 0.8635708484684039 0.4952956395971041 8.486338013959335 9.495950625534562 1.0729913690397648 0.3929655478972317 0.0262848175751703 0.1314977741365594 0.1013218637978259 0.2968544305519885 0.4011198309803483 +Respiratory electron transport 18 48 2.4583182142291764 0.0139589426324537 17.473300970873787 52.5752427184466 0.7619430018929745 0.3962973483509951 7.757662405441163 5.39117119769307 1.7039672197087123 0.3858226471737118 1.0 1.0 0.2386662562546651 0.0096881571670414 0.0002926377590071 +Complex i biogenesis 11 24 2.265350342075129 0.0234911890490443 9.1747572815534 28.546116504854368 0.5440760559261008 0.4236381582634617 4.289696810672699 3.852285850983641 1.2631239118061712 0.3404380044043241 1.0 1.0 0.4055306262621692 0.0099772578106287 0.0012078471674142 +Cellular response to starvation 42 88 2.2642499556209703 0.0235587456458414 41.6747572815534 88.34466019417475 -1.0303047421198284 0.3510932752390905 14.200404878998892 2.6553930524825846 2.028552953689577 0.3779284314527495 1.0 1.0 1.0 0.1098915542911359 0.0009292367493626 +Metabolism of vitamins and cofactors 11 40 2.2485264667245906 0.024542639375634 9.468446601941748 45.929611650485434 -1.0750842825536984 0.3149569447417751 3.9574771941597184 5.663492082419755 1.591669835914462 0.3340430450319153 1.0 0.0249752776964441 0.0078533995953509 0.0137799385434237 0.0260953621935785 +Processive synthesis on the c strand of the telomere 1 9 2.2273157266401262 0.0259261801974348 4.509708737864078 10.978155339805824 -0.4775246369782211 0.4957017371827638 2.5461569961702972 1.9895378043401617 0.8752677202336353 0.3012102484823726 1.0 0.0944323477659319 0.0157589231505245 0.0864662136670167 0.2645195372830358 +Mitochondrial biogenesis 7 31 2.2042564185960187 0.0275063160288069 10.572815533980584 33.521844660194176 0.7125383902440768 0.3998427377933914 4.798567629623383 2.9315837025395943 1.2191838320541302 0.3355715376706868 0.0083366025890121 0.0605318649589048 0.1846346124796731 0.1400734003691514 0.0491041533565925 +Processive synthesis on the lagging strand 1 12 2.1763719654952287 0.0295274583055595 5.337378640776699 12.490291262135925 -0.4682866917213784 0.4841203144335685 2.903004958430143 1.8014026122655222 0.9753460783472956 0.3256071087002858 1.0 0.0771453392642774 0.0104522439456993 0.0595020077672019 0.193069424537178 +Piwi interacting rna pirna biogenesis 1 7 2.111326270249497 0.0347442775332309 2.3932038834951457 9.179611650485436 -0.0581879807658546 0.6357144363215357 1.8263849452238317 1.4284800275084284 0.7132877247734078 0.2707596443100313 1.0 0.0727733471903131 0.0092778495394249 0.0533088961022342 0.1755880027260472 +Sphingolipid de novo biosynthesis 4 10 2.084686243976956 0.0370977901282079 4.08252427184466 10.614077669902912 1.3205451179619188 0.2079933246203462 1.939118365602947 1.3614298144224892 1.289169434780902 0.261809046515659 1.0 0.1280604643503683 0.0290533032515491 0.0044765262200217 0.0110817055396115 +Cdc42 gtpase cycle 7 25 2.0484239043686685 0.0405184812565084 7.257281553398058 31.66747572815534 0.304554686177821 0.6614869417695575 4.162572532194031 5.251778287537443 0.6843163757439207 0.2978793385828449 1.0 0.4708564934485306 0.7133005339071586 0.6149767456508883 0.3079511947767217 +Response of eif2ak4 gcn2 to amino acid deficiency 34 76 2.0128546898602635 0.0441299184633625 39.550970873786405 76.03155339805825 -1.127048342201767 0.3185079045659907 13.761485019110056 1.5173669435319213 2.220942857496925 0.3803423215749384 1.0 1.0 1.0 0.0706337925991679 0.0004886183363472 +Transcription coupled nucleotide excision repair tc ner 3 39 1.9746239550602491 0.0483108384981347 13.283980582524272 45.16747572815534 -0.2751300777856852 0.6349488224302674 6.44615002729383 4.795690868853523 0.7451292206288705 0.2998380220239901 1.0 0.0568079337981731 0.0398581506513103 0.1274955552623762 0.352716998232381 +Regulation of localization of foxo transcription factors 2 7 1.9668680393281632 0.0491984260213178 2.5533980582524274 5.660194174757281 0.2568823734564429 0.4667136608748671 1.787106764891914 0.9301153290871836 1.047460952671123 0.3086493942184483 1.0 1.0 0.1135034587553153 0.0030929731790992 0.0215291267260604 diff --git a/msigdb_reactome/metrics.json b/msigdb_reactome/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..da56bb79b83ddf23675decad72eb0b4c0a16a2df --- /dev/null +++ b/msigdb_reactome/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2772, + "annotations_size": 1359, + "title": "Average number of proteins per term", + "value": 18.181751287711553 +} \ No newline at end of file diff --git a/msigdb_reactome/paths.json b/msigdb_reactome/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..637e5120db6cb4d65ef76cc1ffa70a7040862d9d --- /dev/null +++ b/msigdb_reactome/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_reactome/fragment/C321/C321_val_log2fc"} \ No newline at end of file diff --git a/msigdb_reactome/result.tsv b/msigdb_reactome/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c4e2adbf08d4c26f6d039a41f3870073f902827d --- /dev/null +++ b/msigdb_reactome/result.tsv @@ -0,0 +1,498 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mitochondrial protein import 0.7415173932122318 3.6660050550561536 0.0002463690566252 0.2845594690576513 0.0090095796431423 35 Q13505,O60830,Q99595,Q9Y5L4,Q9Y584,Q9NS69 6 +Protein localization 0.524904272105078 2.8418745681614306 0.0044849133053612 0.9977765738295123 0.0734337009877827 67 Q13505,O60830,O14925,Q9Y276,Q99595,P51648,O15254,P09601,Q9Y5L4,P46379,Q9Y584,Q9NS69 12 +Cristae formation 0.7415467089328313 2.8253763661095515 0.0047225108874584 0.998392531117357 0.0754877015536876 20 Q13505 1 +Endogenous sterols 0.987364620938628 2.652257680251026 0.0079955496393842 0.999981718565763 0.1025089807539918 2 Q16850 1 +Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 0.5277811782748836 2.6237944614910385 0.0086956242940525 0.9999929960260052 0.1084160863818114 58 Q12931,Q9BQ95,P14927,P00846,O75947,P51970,Q86Y39,Q9NX14,O14949,P13073,Q9UDW1,O75489,P15954,Q16795,P56385,Q16718,P06576,O75306,Q7L592,P09669,Q8TB37,P36542,O43676,O75251 24 +Cargo trafficking to the periciliary membrane 0.6947744583631659 2.5623199692167944 0.0103975477868452 0.9999993220828236 0.1239497144063389 20 A6NIH7,Q96A65 2 +Organelle biogenesis and maintenance 0.4533703756431677 2.5250282097939656 0.0115689002303229 0.9999998644312408 0.1367142209826863 83 Q13505,A6NIH7,Q96A65,P00846 4 +Respiratory electron transport 0.5312819373425998 2.4583182142291764 0.0139589426324537 0.9999999949498616 0.1493716774606669 48 P13073,O75306,Q7L592,P09669,P51970,Q9UDW1,Q8TB37,Q9BQ95,O75489,P15954,P14927,Q86Y39,O43676,Q16795,O75251,Q16718,Q9NX14,O14949 18 +Downregulation of erbb2 erbb3 signaling 0.9259927797833928 2.3878488487723786 0.0169473102687207 0.9999999999183672 0.1718760795163545 2 P31749 1 +Akt phosphorylates targets in the nucleus 0.9259927797833928 2.3878488487723786 0.0169473102687207 0.9999999999183672 0.1718760795163545 2 P31749 1 +Regulation of gene expression in beta cells 0.9259927797833928 2.3878488487723786 0.0169473102687207 0.9999999999183672 0.1718760795163545 2 P31749 1 +Complex i biogenesis 0.618886506487301 2.265350342075129 0.0234911890490443 0.9999999999999908 0.2274540023194522 24 O75306,Q7L592,P51970,Q8TB37,O75489,Q9BQ95,O43676,Q86Y39,Q16795,Q16718,Q9NX14 11 +Cellular response to starvation 0.4228683273122679 2.2642499556209703 0.0235587456458414 0.9999999999999916 0.2274540023194522 88 P36543,P62906,P47914,P18077,Q6IAA8,P42345,P62249,P62910,Q9Y3U8,P62899,P62753,P62424,P62841,P32969,P63173,P62263,P62081,P15880,P30050,P62861,P62241,P21281,P35268,P62244,P62829,P62269,P39019,P62750,P61247,P08865,P62277,P05388,P46781,P46779,P61353,P42766,P21283,P18124,P26373,P05387,P61254,Q9Y2Q5 42 +Metabolism of vitamins and cofactors 0.5169234651141908 2.2485264667245906 0.024542639375634 0.999999999999998 0.2332408874929138 40 Q13057,O00764,Q6NUM9,P31749,P00374,Q9H2D1,P09455,Q9BQG2,Q9HCC0,P33527,P43490 11 +Processive synthesis on the c strand of the telomere 0.8295574178086986 2.2273157266401262 0.0259261801974348 0.9999999999999996 0.242941579343222 9 P18858 1 +Mitochondrial biogenesis 0.5689927095282601 2.2042564185960187 0.0275063160288069 1.0 0.2487455706655008 31 Q13505,Q04837,P00846,Q5XKP0,P56385,P04179,P54619 7 +Processive synthesis on the lagging strand 0.7371741022728553 2.1763719654952287 0.0295274583055595 1.0 0.2597927487950964 12 P18858 1 +Piwi interacting rna pirna biogenesis 0.8571795028783641 2.1113262702494975 0.0347442775332309 1.0 0.2879114217540296 7 P19388 1 +Sphingolipid de novo biosynthesis 0.7708600635385884 2.0846862439769556 0.0370977901282079 1.0 0.3055292714706707 10 P51648,Q9Y5P4,Q06136,O95470 4 +Cdc42 gtpase cycle 0.5801926525487471 2.0484239043686685 0.0405184812565084 1.0 0.3220152984069884 25 Q9UQB8,P14923,Q9NSV4,P52565,Q9H0H5,Q6IAA8,O00161 7 +Response of eif2ak4 gcn2 to amino acid deficiency 0.4274195419211447 2.0128546898602635 0.0441299184633625 1.0 0.3367424638041695 76 P62906,P47914,P18077,P62249,P62910,Q9Y3U8,P62899,P62753,P62424,P62841,P32969,P63173,P62263,P62081,P15880,P30050,P62861,P62241,P35268,P62829,P62244,P62269,P39019,P62750,P61247,P08865,P62277,P05388,P46781,P61353,P42766,P18124,P26373,P05387 34 +Ticam1 traf6 dependent induction of tak1 complex 0.8361010830324898 1.9884753709675584 0.0467591402611531 1.0 0.3367424638041695 2 O43318 1 +Irak2 mediated activation of tak1 complex 0.8361010830324898 1.9884753709675584 0.0467591402611531 1.0 0.3367424638041695 2 O43318 1 +Traf6 mediated induction of tak1 complex within tlr4 complex 0.8361010830324898 1.9884753709675584 0.0467591402611531 1.0 0.3367424638041695 2 O43318 1 +Alpha protein kinase 1 signaling pathway 0.8361010830324898 1.9884753709675584 0.0467591402611531 1.0 0.3367424638041695 2 O43318 1 +Activation of ppargc1a pgc 1alpha by phosphorylation 0.8357400722021646 1.9868444966774952 0.0469396319068338 1.0 0.3367424638041695 2 P54619 1 +Transcription coupled nucleotide excision repair tc ner 0.4853721633737455 1.9746239550602491 0.0483108384981347 1.0 0.3437404686856815 39 P18858,P35244,P19388 3 +Regulation of localization of foxo transcription factors 0.8216022746711854 1.9668680393281632 0.0491984260213178 1.0 0.34420619730579 7 Q9Y3B8,P31749 2 +Downregulation of erbb2 signaling 0.8434360170856281 1.9434035574372812 0.0519674177866091 1.0 0.3496223800594152 6 Q9UNE7,P31749 2 +Translation of replicase and assembly of the replication transcription complex 0.825631768953067 1.9410999128675095 0.0522461596415309 1.0 0.3497661623292635 2 Q8WUX9 1 +Eukaryotic translation elongation 0.4182994063440802 1.9331646479841895 0.0532159182148872 1.0 0.3545119257550577 77 P62906,P47914,P18077,P62249,P62910,Q9Y3U8,P62899,P62753,P62424,P62841,P32969,P63173,P62263,P62081,P15880,P30050,P62861,P62241,P35268,P62244,P62829,P62269,P39019,P62750,P61247,P08865,P62277,P05388,P46781,P61353,P42766,P18124,P26373,P05387 34 +Mastl facilitates mitotic progression 0.8554978285831301 1.907321974071891 0.0564789063767836 1.0 0.3691179336532484 5 P14635 1 +Rac2 gtpase cycle 0.5375089592313456 1.896112341770024 0.0579451909612782 1.0 0.3691179336532484 29 Q13505,O15173,Q9NSV4,P52565,Q9H0H5 5 +Translocation of slc2a4 glut4 to the plasma membrane 0.5053307391777592 1.88002897944653 0.0601041285043255 1.0 0.378155141839715 34 P68371,Q96KP1,Q04917,P31749,P31751,Q8TAG9,O00161,Q9Y3B8,Q96A65,P54619 10 +Selenoamino acid metabolism 0.3918444001275844 1.870785221830082 0.061374856783098 1.0 0.3791553279851082 89 P62906,P47914,P18077,P62249,P62910,Q9Y3U8,P62899,P62753,Q16881,P62424,P62841,P49591,P32969,P63173,P62263,P62081,P15880,P30050,P62861,P62241,P35268,P62244,P62829,P62269,P39019,P62750,P61247,P08865,P62277,P05388,P46781,P61353,P42766,P18124,P26373,P05387 36 +Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex 0.7211536335346191 1.8581605019431329 0.0631462251797043 1.0 0.3825267894009247 10 P14635 1 +Insulin processing 0.7681754359237514 1.8581412923384484 0.0631489523285022 1.0 0.3825267894009247 8 Q96KP1,Q8TAD4,Q96A65 3 +Synthesis of ip2 ip and ins in the cytosol 0.8072202166064963 1.857397175397429 0.063254668052457 1.0 0.3825267894009247 2 Q01968 1 +Activation of bad and translocation to mitochondria 0.7401062736915996 1.8369286745048108 0.0662204255468339 1.0 0.3852405848443819 9 Q9Y3B8,P31751,P31749 3 +Signaling by vegf 0.5386746818516325 1.8364666242063816 0.0662886738995065 1.0 0.3852405848443819 27 Q9UQB8,P20936,P31749,P31751,P04792 5 +B wich complex positively regulates rrna expression 0.5962127419906068 1.8236434034081197 0.0682060003029074 1.0 0.3918526719854641 17 O15160,O60264,P19388,Q9H9Y6,O95602,P62805,P35659 7 +Transcriptional regulation of granulopoiesis 0.7598089165854112 1.8222467987883184 0.0684175465662231 1.0 0.3918526719854641 8 P40763,Q03164,P35659,Q13951 4 +Rho gtpase cycle 0.3666236629188715 1.7814687789195471 0.0748359009046597 1.0 0.4070687118807687 136 Q13505,Q9UQB8,O95202,Q8NBN3,Q02952,P52565,O43396,Q5JTV8,Q92783,Q9NQW6,Q96KM6,Q96HY6,Q96JJ3,Q01968,O75489,Q9BX68,Q9H0H5,O15173,P51648,P14923,P30519,Q9NSV4,P80723,O00161,P15924 25 +Cytochrome p450 arranged by substrate type 0.9730757033770168 1.781177897610137 0.0748833932026262 1.0 0.4070687118807687 3 Q16850 1 +Heme degradation 0.8230599056860012 1.7811749842075868 0.0748838689994055 1.0 0.4070687118807687 5 P30519,P33527 2 +Eukaryotic translation initiation 0.3852139584629524 1.769604545804219 0.0767930410647466 1.0 0.4126270345763446 100 P62906,P47914,P08708,P18077,P11940,P62249,P62910,Q9Y3U8,P62899,P62753,P62424,P62841,P32969,P63173,P62263,P62081,P15880,P30050,P62861,P62241,P35268,P62244,P62829,P62269,P39019,P62750,Q04637,P61247,Q7L2H7,P08865,O60841,P62277,P05388,P61254,P46781,P46779,P61353,P42766,P18124,P26373,Q14152,P05387,O75822,O00303 44 +Mtor signalling 0.5940919325450328 1.7676413939630908 0.0771208732762263 1.0 0.4126270345763446 16 P31749,Q9Y376,P31751,Q6IAA8,Q96B36,P62753,P54619 7 +Telomere maintenance 0.476340219563207 1.7613787127716172 0.0781743255343059 1.0 0.4134899883165319 36 P18858,P19388 2 +Runx1 regulates genes involved in megakaryocyte differentiation and platelet function 0.7002013934190484 1.7612568335209642 0.0781949426029056 1.0 0.4134899883165319 10 Q03164,Q13951 2 +Srp dependent cotranslational protein targeting to membrane 0.3825118716607414 1.7480755591929011 0.0804509445064716 1.0 0.4188997455336969 90 P62906,P47914,P67812,P18077,P08240,P62249,P62910,Q9Y3U8,P62899,P62753,P62424,P62841,P32969,P63173,P62263,P62081,P15880,P43307,P30050,P62861,P04844,P62241,P04843,P35268,P62244,P62829,P62269,P39019,P62750,P61247,P08865,P62277,P05388,P46781,P61353,P42766,P18124,P26373,P05387 39 +Resolution of abasic sites ap sites 0.5371827350097249 1.736730079694477 0.0824348257633758 1.0 0.4206601603968952 24 P18858,P13051,P35244,Q07864 4 +Polb dependent long patch base excision repair 0.7910739330766087 1.7342107381392151 0.0828806983665328 1.0 0.4206601603968952 6 P18858 1 +Esr mediated signaling 0.4562336662521122 1.7270106134563117 0.0841657573824354 1.0 0.4236343121582586 40 P19388,P31749,P31751,Q13951,P04792,P04899 6 +Cdc6 association with the orc origin complex 0.7768953068592037 1.7185621306171248 0.085694132166131 1.0 0.4297355188700079 2 Q9UBD5 1 +Metabolism of water soluble vitamins and cofactors 0.4890100857678916 1.7025472156660637 0.0886528353441238 1.0 0.441315762757012 33 Q13057,O00764,P00374,Q9H2D1,Q9HCC0,P33527,P43490 7 +Chromosome maintenance 0.4535221954217474 1.69949316696865 0.0892263009535767 1.0 0.4425494269923752 39 P18858,P19388 2 +Inhibition of dna recombination at telomere 0.6853949839074779 1.6923156954845917 0.0905857967791057 1.0 0.4460365863145096 10 Q9UER7,P19388,P46100 3 +Positive epigenetic regulation of rrna expression 0.5201756624646077 1.6771066452842305 0.0935216295738878 1.0 0.4501591301736863 26 O15160,O60264,P19388,P62805,Q9H9Y6,O95602,P16104,Q86YP4,P35659 9 +Nonsense mediated decay nmd 0.3780437606773358 1.6741634972158583 0.0940984712935297 1.0 0.4501591301736863 85 P62906,P47914,P18077,P11940,P62249,P62910,Q9Y3U8,P62899,P62753,P62424,P62841,P32969,P63173,P62263,P62081,P15880,P30050,P62861,P62241,P35268,P62244,P62829,P62269,P39019,P62750,Q04637,P61247,P08865,P62277,P05388,P46781,P61353,P42766,P18124,P26373,P05387 36 +Peptide hormone metabolism 0.6353996227625045 1.6723687906288272 0.0944516223618623 1.0 0.4501591301736863 12 Q96KP1,Q8TAD4,Q96A65,Q8TAG9 4 +Activation of bh3 only proteins 0.6581800344827233 1.6709301495902196 0.0947354755185241 1.0 0.4501591301736863 11 Q9Y3B8,P31751,P31749 3 +Tp53 regulates transcription of genes involved in g2 cell cycle arrest 0.723680924081791 1.666018829711536 0.0957096640781096 1.0 0.4532036009831046 8 P14635 1 +Rna polymerase i transcription 0.5350442515533519 1.6605784529647056 0.0967981394265979 1.0 0.4551857144662514 21 O15160,P19388,P62805,O95602,Q9H9Y6,P16104,Q86YP4,P18074 8 +Nucleotide excision repair 0.4440370700062679 1.6555959425453015 0.0978036724207696 1.0 0.4583282442062961 46 P18858,P35244,P19388,Q07864 4 +Vxpx cargo targeting to cilium 0.7182998554773714 1.6425909183822294 0.1004676010205838 1.0 0.4671677728396965 8 Q96KP1,Q96A65 2 +Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s 0.4373423872756136 1.6326746792542712 0.1025374355682844 1.0 0.4681441004668777 50 P62841,P62244,P62269,P39019,P62263,P62081,P15880,Q04637,P61247,Q7L2H7,Q14152,P11940,P62861,O75822,O00303,P62249,P62241,P62753 18 +Estrogen dependent nuclear events downstream of esr membrane signaling 0.7846464387150832 1.6301125364953737 0.103077714611323 1.0 0.4681441004668777 5 P31749 1 +Resolution of ap sites via the multiple nucleotide patch replacement pathway 0.5381274389962581 1.6246231324183489 0.1042428850612411 1.0 0.4706514312233445 20 P18858,P35244,Q07864 3 +Runx2 regulates genes involved in cell migration 0.9263271939328248 1.6105468324738066 0.1072785300959793 1.0 0.4764428836615552 3 Q13951,P31749 2 +Activated tak1 mediates p38 mapk activation 0.7741181798390193 1.5884297392554358 0.1121891970998767 1.0 0.4893370984220493 5 O43318,P61088,Q15750 3 +Rac3 gtpase cycle 0.4942937315197211 1.586338327360804 0.1126625823571076 1.0 0.4893370984220493 29 Q9UQB8,Q01968,O15173,Q9NSV4,Q9H0H5,Q6IAA8,O00161 7 +Formation of incision complex in gg ner 0.63715769198344 1.5684056460095446 0.1167864943100776 1.0 0.4984803878426289 11 P18074,P35244,Q9UGN5,P61088 4 +Metabolism of porphyrins 0.6801417730850197 1.5674522916526032 0.1170090093611468 1.0 0.4984803878426289 9 P30519,P33527 2 +Cell death signalling via nrage nrif and nade 0.6576718789800711 1.5623135812562732 0.1182141341145852 1.0 0.4995370092488459 10 P42575,Q9NY61,Q14155,Q92542,Q92974,P42574 6 +Inlb mediated entry of listeria monocytogenes into host cell 0.7608377395699093 1.5357014095556307 0.1246116292176191 1.0 0.5074579206468633 5 Q9NWH9 1 +Rna polymerase i promoter escape 0.6077873514740195 1.5319867577518196 0.1255257025624712 1.0 0.5074579206468633 12 O15160,P19388,P62805,O95602,Q9H9Y6,P18074 6 +Pcna dependent long patch base excision repair 0.5447569827642511 1.524726382424273 0.1273273584945631 1.0 0.5074579206468633 17 P18858,P35244 2 +Mecp2 regulates transcription of neuronal ligands 0.9014675955779772 1.5192580383354264 0.1286975574989686 1.0 0.5074579206468633 3 Q96ST3 1 +Leishmania infection 0.4470100080378005 1.5182958864213705 0.1289398242315791 1.0 0.5074579206468633 36 Q9UQB8,P09601,P63218,P04899,Q9Y3E5 5 +Transcriptional regulation by runx2 0.4223265392565793 1.5138259952514013 0.1300699776609399 1.0 0.5074579206468633 52 P55036,O00487,P31749,P49721,P31751,Q13951,Q9UNE7,P14635 8 +Visual phototransduction 0.7366542954676678 1.5131793868001069 0.1302340987342818 1.0 0.5074579206468633 6 P09455 1 +Apoptosis induced dna fragmentation 0.6459107840327171 1.506847197093714 0.1318498286530554 1.0 0.5104954904259325 10 P42574,P07305,P10412,P16403 4 +Base excision repair 0.4905044049285053 1.501148629866644 0.133317123217308 1.0 0.5110190931787362 27 P18858,P13051,P35244,Q07864 4 +Gap filling dna repair synthesis and ligation in gg ner 0.540700966286465 1.5009244790418426 0.1333750959301358 1.0 0.5110190931787362 17 P18858,P35244 2 +Mecp2 regulates neuronal receptors and channels 0.7097619261779783 1.500483644257714 0.1334891670923115 1.0 0.5110190931787362 7 Q96ST3,P51608,Q9NWH9 3 +Runx1 regulates transcription of genes involved in differentiation of hscs 0.4286476681992524 1.4915194198684958 0.1358251764911142 1.0 0.5121484280582168 42 P55036,O75832,O00487,Q03164,P62805,P49721,P28072,Q13951,Q14997 9 +Amino acid transport across the plasma membrane 0.7270758122743652 1.4884941799201168 0.1366206158938911 1.0 0.5121484280582168 2 P08195 1 +Formation of atp by chemiosmotic coupling 0.6412682695081562 1.484908461485246 0.137568074283906 1.0 0.5121484280582168 10 P00846 1 +Extra nuclear estrogen signaling 0.5484941201819398 1.479137515367467 0.139103565403349 1.0 0.5121484280582168 15 P04792,P04899,P31751,P31749 4 +Rna polymerase i transcription initiation 0.5360741824095676 1.473739869868406 0.1405516436248961 1.0 0.5148508994238109 17 O15160,P19388,Q9H9Y6,O95602,Q86YP4,P18074 6 +Formation of senescence associated heterochromatin foci sahf 0.695614169584994 1.4404506446965988 0.1497399440658053 1.0 0.5355173262774461 7 P07305,P17096,P16403 3 +Hsf1 activation 0.5388572535712386 1.424436647474412 0.1543201119507335 1.0 0.5355993156117654 15 P04792,P35244 2 +Signaling by hippo 0.7149819474553841 1.4243777872196566 0.1543371407631601 1.0 0.5355993156117654 6 Q4VCS5,Q13043,P42574 3 +Rac1 gtpase cycle 0.4532791246319823 1.4238419692500874 0.1544922234877204 1.0 0.5355993156117654 33 Q9UQB8,Q9NSV4,P52565,Q9H0H5,Q6IAA8,O00161 6 +The citric acid tca cycle and respiratory electron transport 0.3563561796130278 1.4190526068892395 0.1558836795282643 1.0 0.5390481437122423 88 Q12931,Q9BQ95,P14927,Q15120,Q96I99,P00846,O75947,P51970,Q86Y39,Q9NX14,O14949,P13073,Q9UDW1,O75489,P15954,Q16795,P56385,Q16718,P06576,P11177,P07954,Q7L592,Q04760,P09669,Q8TB37,P36542,O75306,P23368,O43676,O75251 30 +Signaling by nuclear receptors 0.4101926932416485 1.4094143254165952 0.1587126905607476 1.0 0.546052016384952 53 P19388,P62805,P31749,P31751,Q13951,P04792,Q01469,P63218,P04899,O00767 10 +Abc family proteins mediated transport 0.4112560497545308 1.4079459864043091 0.1591470645816466 1.0 0.5461637898142873 52 P55036,O75832,O00487,O75027,P49721,P28072,Q9BUN8,P33527,Q8NE71,O15439,Q9NRK6 11 +Regulation of tp53 activity through association with co factors 0.8675401124222328 1.3943001841564022 0.1632269753456912 1.0 0.5531806969944996 3 P31749 1 +Negative regulation of nmda receptor mediated neuronal transmission 0.723812685568254 1.3879857011746368 0.1651413992396717 1.0 0.5582765213102335 5 P49593,P07196 2 +Dual incision in tc ner 0.464989819306329 1.3734416629578328 0.1696150851839739 1.0 0.5653446372772049 29 P35244,P19388 2 +Regulation of tp53 activity through acetylation 0.6176078609508551 1.37278203001849 0.1698201188355557 1.0 0.5653446372772049 10 P31751,P31749 2 +G beta gamma signalling through pi3kgamma 0.7161214945030938 1.3572040352429136 0.174716388944339 1.0 0.572607105360081 5 P31751,P31749 2 +Transport of small molecules 0.3410084889188426 1.3567585367424086 0.1748579460812609 1.0 0.572607105360081 134 O95202,O75832,P33527,Q8WTV0,P63218,Q8TAD4,O75027,P49721,Q8N4V1,Q8NE86,Q96TA2,Q9UBX3,P55036,P21281,O00487,P28072,Q70HW3,Q9BUN8,Q8NE71,O15439,O94973,Q8TB61,Q9C0H2,P30519,P09601 25 +Phase i functionalization of compounds 0.5517869715291118 1.3520168421082674 0.1763699275354509 1.0 0.5747883249896348 13 Q16850,P22570 2 +Mismatch repair 0.5897910145463142 1.3353596848742757 0.181758652884949 1.0 0.5873583734390855 11 P18858 1 +Signaling by rho gtpases miro gtpases and rhobtb3 0.3229016624955106 1.3341930253396166 0.1821406047443858 1.0 0.5873583734390855 222 Q13505,Q9UQB8,P04350,O95202,P68371,Q8NBN3,P84095,Q02952,P52565,Q6IAA8,O43396,Q5JTV8,Q92783,Q53HL2,P62805,Q12792,Q99661,Q9NQW6,O43237,Q9BZD4,Q96KM6,Q2NKX8,Q96HY6,O15498,Q9HBM1,Q96JJ3,Q01968,Q04917,P50748,O75489,Q16539,Q9BX68,Q9H0H5,O95140,O43663,O75116,O15173,P51648,P14923,P30519,Q9NSV4,Q9P2R3,P80723,O00161,O00139,Q9Y3B8,Q86XL3,P15924 48 +Class b 2 secretin family receptors 0.8511807388068228 1.3339875450976828 0.182207938392735 1.0 0.5873583734390855 3 Q9Y3E5 1 +Hiv elongation arrest and recovery 0.5181358510385934 1.3323642088595458 0.182740537229892 1.0 0.5873583734390855 16 P19388 1 +G protein beta gamma signalling 0.6900722253611744 1.32196829391683 0.1861787090465525 1.0 0.5925453526797774 6 P31751,P31749 2 +Cd28 dependent pi3k akt signaling 0.8467128596203028 1.317517878368148 0.1876650923056551 1.0 0.5944915161850473 3 P31749 1 +Cellular response to chemical stress 0.3742752570646525 1.3139779293517924 0.1888536316134996 1.0 0.5968653147970838 71 P55036,O75832,P13073,P09669,O00487,P49721,Q96ST3,P28072,P30519,P09601,P33527,P40763,P04179,Q16881,Q14997 15 +Negative epigenetic regulation of rrna expression 0.4809015944048838 1.3124005822556786 0.1893850105386429 1.0 0.5971559845058372 21 O15160,O60264,P19388,P62805,Q9H9Y6,O95602,Q96ST3,Q9UHR5,P18074 9 +Rna polymerase i transcription termination 0.623645523486566 1.3096465203331351 0.1903154431598825 1.0 0.5987006649404639 9 O15160,P18074,P19388,Q9H9Y6 4 +Lagging strand synthesis 0.4987729097459878 1.290853203448287 0.1967545850275631 1.0 0.6119915960994512 18 P18858 1 +Negative regulation of met activity 0.6821730253516172 1.289448168810481 0.197242324570684 1.0 0.6119915960994512 6 Q9NWH9 1 +Negative regulation of the pi3k akt network 0.5395987525843449 1.2865747485567125 0.1982425497575231 1.0 0.6136939068803505 13 Q9NWH9,P31749 2 +Tp53 regulates transcription of cell cycle genes 0.5151701255059884 1.26602734311126 0.2055032930716376 1.0 0.6275932028861922 14 P14635 1 +Developmental biology 0.3186189544233636 1.2619663766127562 0.2069608854611782 1.0 0.6287005735043465 235 P04350,Q01518,Q03164,P19388,Q16850,Q06323,P62753,P62424,O95239,P49721,P19784,P62263,P62081,P30050,O00487,P31749,P16104,Q04637,Q9NWH9,Q15369,P42766,Q9Y490,Q13951,Q13885,P17612,Q13617,Q00169,Q8TEY7,P62906,P62249,P62910,Q9Y3U8,P62899,P50570,Q71SY5,P62841,O75448,O15145,P32969,P35241,P15880,P26038,Q02750,P62241,P55036,P20936,P61247,P31751,P08865,O43242,O94973,P05388,P07384,P08238,Q14195,P61353,P14923,P18124,P15924,O75832,P18077,P11940,P36507,P62861,P62244,P62269,P39019,P28072,P62750,P40763,P05387,P35659,P68371,Q14997,P62805,Q92542,P35268,Q16539,P62333,O75116,Q96S59 81 +Sensory perception 0.4710998528080786 1.2616517172929032 0.2070741377691494 1.0 0.6287005735043465 22 Q6IBS0,P49356,Q6NUM9,P56545,P09455,P26038 6 +Nuclear signaling by erbb4 0.8314143084934551 1.2611529182690269 0.2072537578586808 1.0 0.6287005735043465 3 P16949 1 +G2 m dna replication checkpoint 0.82981088182844 1.25524922244465 0.2093883019704505 1.0 0.6312618204399869 3 P14635 1 +Cobalamin cbl vitamin b12 transport and metabolism 0.8290141505934465 1.2523160669544249 0.2104547165856489 1.0 0.6312618204399869 3 P33527 1 +Base excision repair ap site formation 0.689648203137404 1.2511353194035773 0.210885111464131 1.0 0.6312618204399869 5 P13051,P29372,P62805 3 +Autophagy 0.4012066603115924 1.248907048750706 0.2116990731981034 1.0 0.6313255388467252 43 P68371,P04350,O95140,Q8WUX9,O43633,O43237,Q8N4H5,Q6IAA8,P61088,P60520,Q9NS69,Q9Y4P1,P54619 13 +Pink1 prkn mediated mitophagy 0.6489815761838423 1.2417992621413654 0.2143106350545114 1.0 0.6313255388467252 7 Q9NS69,O95140 2 +Telomere c strand lagging strand synthesis 0.4828247634783711 1.2336186256501809 0.2173450492025583 1.0 0.6366298269296053 19 P18858 1 +Cytoprotection by hmox1 0.3789688724327499 1.2335706290654356 0.2173629431165098 1.0 0.6366298269296053 62 P55036,O75832,P13073,P09669,O00487,P49721,Q96ST3,P28072,P30519,P09601,P33527,P40763,Q14997 13 +Ca2 pathway 0.6667950534050041 1.2261228807330211 0.2201524366805056 1.0 0.6406577332950903 6 Q08209,O43318 2 +Signaling by erbb2 0.5831405948768231 1.2089160043836118 0.2266951168470266 1.0 0.6554865187129981 10 Q9UNE7,P31749 2 +Cd163 mediating an anti inflammatory response 0.6660649819494546 1.205785735744431 0.2279001168875618 1.0 0.6575716748411816 2 Q16539 1 +Robo receptors bind akap5 0.6653429602888048 1.202451344936469 0.2291887062758046 1.0 0.6580847217698268 2 P17612 1 +Cd28 co stimulation 0.6397134404491875 1.202275746469608 0.2292567104813974 1.0 0.6580847217698268 7 P31749 1 +Foxo mediated transcription 0.5434526852305486 1.2015687539764677 0.2295306535091228 1.0 0.6580847217698268 12 Q96ST3,Q9Y3B8,P31751,P31749 4 +Hiv transcription elongation 0.4829911367498039 1.1955582989091782 0.2318689729999246 1.0 0.6588564292823036 18 P19388 1 +Akt phosphorylates targets in the cytosol 0.6752414652049743 1.1934104289348422 0.2327086725941911 1.0 0.6588564292823036 5 P31749 1 +Tp53 regulates metabolic genes 0.413052319866286 1.187865966929485 0.2348862198160892 1.0 0.6624492030189323 35 P13073,P09669,P31749,P31751,Q6IAA8,Q9Y3B8,Q16881,P54619 8 +Mrna splicing minor pathway 0.4390752336304476 1.1845126048371597 0.2362102096501823 1.0 0.6624492030189323 29 P62314,Q15427,Q86XP3,P19388 4 +Gaba receptor activation 0.6565610935322418 1.1839953322085022 0.2364149105696704 1.0 0.6624492030189323 6 P04899,Q9Y639 2 +Vegfr2 mediated vascular permeability 0.5755082154765381 1.1726311892308956 0.2409437364247733 1.0 0.6702732199409972 10 P31751,P31749 2 +Other interleukin signaling 0.8058879643169442 1.1673125240327402 0.2430841827676082 1.0 0.6723689233844615 3 P42574 1 +Resolution of sister chromatid cohesion 0.3849902666922621 1.1664830199263296 0.2434192098972936 1.0 0.6723689233844615 53 P68371,Q9HBM1,Q53HL2,Q7Z5K2,P50748,Q9BZD4,O43237,Q2NKX8,O00139,P14635,Q9NTI5 11 +Interleukin 4 and interleukin 13 signaling 0.5362785198716429 1.164649025370308 0.244161090491136 1.0 0.6723689233844615 12 P09601,P31749 2 +Signaling by fgfr in disease 0.4970462206852162 1.1642158824284126 0.244336535380639 1.0 0.6723689233844615 14 O95429,P19388,Q16630 3 +Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 0.5359728402358136 1.1630765287744629 0.2447984540480328 1.0 0.6723689233844615 12 O43318,P09601,P61088,Q15750 4 +Pi3k akt signaling in cancer 0.5355932356367706 1.161123824173093 0.2455915474189551 1.0 0.6723689233844615 12 Q9NWH9,P31749 2 +Epigenetic regulation of gene expression 0.3980864895529198 1.1581342426486794 0.2468092579080951 1.0 0.673521649592573 37 O15160,O60264,P19388,P62805,Q9H9Y6,O95602,Q96ST3,Q9UHR5,P16104,Q86YP4,P18074,P35659 12 +Listeria monocytogenes entry into host cells 0.6282167537556085 1.1532831832209098 0.2487941703071685 1.0 0.6758979500579303 7 Q9NWH9 1 +Condensation of prometaphase chromosomes 0.5887268467245046 1.1496598023576354 0.250284016750369 1.0 0.677561710684764 9 O95347,P19784,Q9BPX3,P14635 4 +Tak1 activates nfkb by phosphorylation and activation of ikks complex 0.6472779095585133 1.145813255143966 0.2518724294119852 1.0 0.6777786099752213 6 O43318,P61088 2 +Aquaporin mediated transport 0.6468312626825251 1.143977254319842 0.2526330701381916 1.0 0.6777786099752213 6 P63218,P17612,Q99797 3 +Infectious disease 0.290661073119031 1.1414983135272827 0.2536626134048139 1.0 0.678597424443193 313 Q9UQB8,O75832,P19388,P18077,P36507,P63218,P04899,Q92783,Q9Y3U8,P62899,Q9UER7,P18858,P62841,P49356,P49721,Q14241,O43237,Q13217,Q86YP4,P62861,P04844,Q5SRE5,P17096,P55036,Q96JJ3,O00487,P62244,P62269,P39019,P28072,Q10567,Q9NWH9,O94973,P20339,Q8WUX9,P61353,P42766,P09601,Q9Y3E5 39 +Metabolism of fat soluble vitamins 0.7970386421090432 1.1348787688602988 0.2564261167294006 1.0 0.6829636753759 3 P09455,Q6NUM9 2 +Transcriptional regulation by mecp2 0.5487865432383486 1.1327154512994633 0.2573337668637778 1.0 0.683040213218504 11 Q13451,Q96ST3,Q9NWH9,Q8WYQ5,P51608 5 +Mtorc1 mediated signalling 0.5641693462510076 1.11878354809355 0.2632324919825202 1.0 0.68927351946868 10 Q04637,P06730,Q96B36,Q6IAA8,P42345,Q9Y2Q5,P62753 7 +Mitochondrial translation 0.3839966939803452 1.1161696970491586 0.2643495029592002 1.0 0.6895412178916567 48 Q96DV4,Q9Y3D9,Q6P1L8,P82664,Q9Y2R5,O75616,Q9NRX2,Q96E11,P46199,Q96EY7,Q9BRJ2,Q13084,P82675,Q9BYD2,Q14197,Q8TAE8,Q9NQ50,Q15070,Q9Y2Q9 19 +E2f mediated regulation of dna replication 0.5626118818617525 1.1113950141366966 0.2663983574950039 1.0 0.6922282367795609 10 P09884,Q9Y619,Q14181,P49642,Q9UBD5,P14635 6 +Cargo recognition for clathrin mediated endocytosis 0.4362993625919934 1.0968011374552806 0.2727283328697174 1.0 0.700380460111833 26 Q92783,O94973,Q8NC96,P20645 4 +Formation of rna pol ii elongation complex 0.4425758495824557 1.0874344779782583 0.2768448408196193 1.0 0.7022342461398842 23 P19388 1 +Regulation of expression of slits and robos 0.3300578570892766 1.0873224965131727 0.2768943098105525 1.0 0.7022342461398842 123 O75832,Q8TEY7,P62906,P18077,P11940,P62249,P62910,Q9Y3U8,P62899,Q06323,P62753,P62424,Q14997,P62841,P49721,P32969,P62263,P62081,P15880,P30050,P62861,P62241,P55036,P35268,O00487,P62244,P62269,P39019,P28072,P62750,Q04637,P61247,Q15369,P08865,O43242,P62333,P05388,P61353,P42766,P18124,P05387,Q13617 42 +Estrogen dependent gene expression 0.4402351068523263 1.0867251385333887 0.2771583007612608 1.0 0.7022342461398842 24 P19388 1 +Tp53 regulates transcription of dna repair genes 0.4420881075543244 1.0842054878928005 0.2782736989695515 1.0 0.7022342461398842 23 Q14241,P19388 2 +Loss of function of mecp2 in rett syndrome 0.7651130514316211 1.0794764557780252 0.2803753839961773 1.0 0.7056113830570464 4 Q96ST3,P51608 2 +Constitutive signaling by akt1 e17k in cancer 0.6298125193844983 1.0741242707053495 0.2827669878966166 1.0 0.7088251861283599 6 P31749 1 +Nrage signals death through jnk 0.6289031531736835 1.0703988031579474 0.2844398377853823 1.0 0.7088251861283599 6 Q92974,Q9NY61,Q14155 3 +Noncanonical activation of notch3 0.6353790613718369 1.0647185306206486 0.2870033218475756 1.0 0.7088251861283599 2 Q92542 1 +Signaling by receptor tyrosine kinases 0.3323989468204593 1.0627615663835892 0.287890092972126 1.0 0.7088251861283599 104 Q9UQB8,P21281,P20936,P19388,P31749,Q96ST3,Q9NWH9,P31751,O94973,P04792,Q92783,Q13043,Q9UNE7 13 +Jnk c jun kinases phosphorylation and activation mediated by activated human tak1 0.7605082850631494 1.0627147409512647 0.2879113338799519 1.0 0.7088251861283599 4 O43318,P61088 2 +Adp signalling through p2y purinoceptor 1 0.7769096016061962 1.0613823477168072 0.288516175797243 1.0 0.7090298063444 3 P63218 1 +Rab regulation of trafficking 0.418325449142061 1.0575280052329945 0.2902706803627723 1.0 0.7107709092126264 30 P31749,P31751,Q7Z392,Q8IUR0,P60520,P20339,Q9Y3P9 7 +Glucuronidation 0.7742867461177242 1.0518400553899272 0.2928729382110195 1.0 0.7145679048990585 3 Q9NUJ1,Q16851 2 +Selective autophagy 0.4170574721900383 1.0481869504649242 0.2945524816543674 1.0 0.7166272251900889 30 P68371,P04350,P19784,O43237,P61088,Q8N4H5,Q9NS69,O95140,P54619 9 +Amyloid fiber formation 0.7560192096363332 1.046397846006638 0.2953773868353404 1.0 0.7166272251900889 4 Q92542,P62805 2 +Death receptor signalling 0.4355491467026079 1.0409700938742776 0.2978894282085123 1.0 0.7166272251900889 23 O43318,Q9NY61,Q92542,Q8TCT8,P52565,P42574,O95429 7 +Global genome nucleotide excision repair gg ner 0.3993270551308821 1.036541630331161 0.2999495282290767 1.0 0.7189266470252473 34 P49916,P18858,P35244,Q9UGN5,P61088,P18074,Q07864 7 +Transcription of the hiv genome 0.4378382049039492 1.034091123735979 0.3010935654655458 1.0 0.719132083422982 21 P19388 1 +Suppression of phagosomal maturation 0.6187705284894014 1.0289497611938851 0.3035032832448419 1.0 0.7231486825922052 6 P20339 1 +Influenza infection 0.3265735021044587 1.0251633275965315 0.3052861287390402 1.0 0.7240555828208651 121 P19388,Q86U42,P62906,P18077,P62249,P62910,Q9Y3U8,P62899,P62753,O00505,P62424,P52294,P62841,P32969,P62263,P62081,P15880,Q13217,P30050,P62861,Q9BVL2,P62241,Q5SRE5,P35268,P62244,P62269,P39019,P62750,P61247,P08865,P05388,P61353,P42766,P27797,P18124,P05387 36 +P75 ntr receptor mediated signalling 0.4669191830741911 1.0150146011233148 0.3100988674511118 1.0 0.7303715092999323 15 P42575,Q9NY61,Q14155,Q92542,P52565,Q92974,P42574 7 +Metalloprotease dubs 0.6069832908216919 0.9809040807023632 0.3266400449606257 1.0 0.7562245674642084 6 O00487 1 +Kinesins 0.4413264192823256 0.9782999454431492 0.3279259968959644 1.0 0.7566825009789576 19 P68371,P04350,Q02241,O95239,Q12756,Q99661,Q9H0H5,O00139 8 +Gaba synthesis release reuptake and degradation 0.6158844765342915 0.9760861277409062 0.3290217851982473 1.0 0.7578654340413866 2 P51649 1 +G alpha s signalling events 0.6045308481032067 0.970935303746964 0.3315804964985673 1.0 0.7611788762526234 6 P04899,Q9Y3E5 2 +Vasopressin regulates renal water homeostasis via aquaporins 0.6180869554941554 0.965706618146762 0.3341910069091822 1.0 0.7616668227053709 5 P17612,P63218,P10644 3 +Glucagon signaling in metabolic regulation 0.6180869554941554 0.965706618146762 0.3341910069091822 1.0 0.7616668227053709 5 P17612,P63218,P10644 3 +Stat3 nuclear events downstream of alk signaling 0.7334138049510308 0.9646553966500506 0.33471744279661 1.0 0.7616668227053709 4 Q96ST3 1 +Rab gefs exchange gtp for gdp on rabs 0.4169793571952567 0.9637345936631648 0.3351790058869484 1.0 0.7616668227053709 26 P31749,P31751,Q7Z392,Q8IUR0,P20339 5 +Cilium assembly 0.3643072438435148 0.96050636628584 0.3368004284562089 1.0 0.7625915437743751 52 A6NIH7,Q96A65 2 +Rhof gtpase cycle 0.4571042207605593 0.9596206942730232 0.3372461499693888 1.0 0.7625915437743751 15 Q5JTV8,P80723,Q9NSV4,O00161 4 +E2f enabled inhibition of pre replication complex formation 0.7315992593350796 0.9581293128569032 0.3379975559542054 1.0 0.7630210607006066 4 Q9UBD5,P14635 2 +Regulation of tp53 expression and degradation 0.4953846468044064 0.9553210671542636 0.339415356923658 1.0 0.7649510282906322 12 P31751,P31749 2 +Mitophagy 0.5270061817906808 0.9434183658979232 0.3454669527250087 1.0 0.7760158491789865 10 Q8N4H5,Q9NS69,O95140 3 +Iron uptake and transport 0.4450608344711394 0.9376759119391652 0.3484109864799984 1.0 0.7802181957906651 17 P21281,P30519,P21283,P02786,P09601 5 +Polo like kinase mediated events 0.7426378091324611 0.937530040839354 0.3484859785466767 1.0 0.7802181957906651 3 P14635 1 +Regulation of beta cell development 0.7415744352497202 0.9337207766101934 0.350447944825941 1.0 0.7833203240435095 3 P31749 1 +Rhoj gtpase cycle 0.4372611264212097 0.921127344975574 0.3569839451549095 1.0 0.7928570146793781 18 Q01968,Q14155,P14923,P02786,Q9NSV4,Q6IAA8,Q15758,P42166,O00161 9 +Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.5217746982896433 0.918956858170849 0.3581181381259042 1.0 0.7928570146793781 10 P51648,P09601 2 +Glucagon like peptide 1 glp1 regulates insulin secretion 0.5915875508116973 0.9185100765974727 0.3583518859545787 1.0 0.7928570146793781 6 P63218,P17612,P10644 3 +Cholesterol biosynthesis 0.4416181288646027 0.9176570725740923 0.3587984282765397 1.0 0.7928570146793781 17 Q16850,Q15392 2 +Nod1 2 signaling pathway 0.5365044812121669 0.9123558365821686 0.3615814298563231 1.0 0.7977096804784791 9 O43318,P61088,Q15750 3 +Synthesis of pips at the plasma membrane 0.570319618279058 0.9085548962812088 0.363585123984629 1.0 0.7991335163937221 7 P20339,Q01968 2 +Foxo mediated transcription of oxidative stress metabolic and neuronal genes 0.7171884773753077 0.9065235951077856 0.364658781905202 1.0 0.7991335163937221 4 Q96ST3 1 +Synthesis of pc 0.6015794912165564 0.9007774399027222 0.3677066648626259 1.0 0.7993103775888042 5 P35790 1 +Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters 0.5319228878484478 0.8917983180296845 0.3725010434129383 1.0 0.799729728275171 9 Q10567 1 +Dna damage telomere stress induced senescence 0.4464042065504132 0.8821464932431055 0.3776975926125476 1.0 0.8080720640108721 14 P07305,P10412,P17096,P16403 4 +Establishment of sister chromatid cohesion 0.5607580841030702 0.8687372567478614 0.3849908583388854 1.0 0.8184953713988982 7 Q7Z5K2 1 +Adora2b mediated anti inflammatory cytokines production 0.5265756039594072 0.8678842221132971 0.3854577172150808 1.0 0.8184953713988982 9 P04899,Q9Y3E5 2 +Signaling by alk 0.5915078653081991 0.8614610723437889 0.3889841521805446 1.0 0.8208532031263356 5 Q96ST3 1 +Factors involved in megakaryocyte development and platelet production 0.3570315025578084 0.8546822364362687 0.3927270871413333 1.0 0.8265001017574878 39 P68371,P04350,Q02241,Q9H4M9,O95239,Q12756,Q96ST3,Q99661,P17612,Q13885,Q9H0H5,O00139,P20339,O95140 14 +Nade modulates death signalling 0.7181633511604053 0.850510590893302 0.3950412747469203 1.0 0.8282576874953002 3 P42574 1 +Mitotic g1 phase and g1 s transition 0.3285704776990986 0.8445037925988438 0.3983879449445289 1.0 0.8282576874953002 74 P55036,O00487,P31749,P49721,P00374,P31751,P35244,P14635,Q07864 9 +Cytosolic sulfonation of small molecules 0.5696845225500192 0.8306844688147488 0.4061519024779816 1.0 0.8388082249633455 6 Q8TB61 1 +Condensation of prophase chromosomes 0.5022303257286476 0.8283214019041264 0.4074885054887667 1.0 0.8388082249633455 10 P14635 1 +Signaling by wnt 0.3205008538158504 0.8266452376647366 0.4084381688443896 1.0 0.8388082249633455 79 O75832,Q14738,Q08209,P63218,Q06323,Q14997,P62805,P49721,P19784,P55036,O00487,O43318,P31749,P28072,P31751,P62333,O94973,O75436,P56545 19 +Extension of telomeres 0.3934382240249501 0.8212903748854359 0.4114808888973966 1.0 0.8421724819451236 27 P18858 1 +Sealing of the nuclear envelope ne by escrt iii 0.5137679549408944 0.8110004014805829 0.4173654401918352 1.0 0.8492606985856636 9 Q8WUX9,P04350,O43633,P68371 4 +Transcriptional regulation by tp53 0.3130822469030764 0.8058590186289953 0.4203241433446678 1.0 0.8492606985856636 107 P19388,Q6IAA8,Q9UER7,Q16881,P14635,A5YKK6,Q14004,P19784,Q14241,Q86YP4,P35244,P18074,P13073,P42771,Q04917,P31749,Q16539,P15954,P31751,Q15369,Q96KQ7,P09669,Q8WX92,Q9Y3B8,P54619 25 +Uptake and function of anthrax toxins 0.705308775731311 0.805435529334643 0.4205683959883382 1.0 0.8492606985856636 3 Q02750,P36507 2 +Energy dependent regulation of mtor by lkb1 ampk 0.5448959832272855 0.8032793319692179 0.4218133011256846 1.0 0.8505107955931831 7 Q9Y376,P54619 2 +Rhog gtpase cycle 0.3722899072174798 0.794112977776648 0.4271296631167256 1.0 0.8561492804950297 33 O95202,P34897,Q96JJ3,O15173,P84095,O75489,P02786,Q9NSV4,P52565,P61604,Q86UP2,Q6IAA8,P42166,P42167,Q16718,Q86XL3,O15498 17 +Cyclin a cdk2 associated events at s phase entry 0.3493822241532001 0.7877307923040824 0.4308541902027483 1.0 0.8586776517206077 42 P55036,O75832,O00487,P31749,P49721,P31751 6 +Endosomal sorting complex required for transport escrt 0.540848290625233 0.7867138671452257 0.4314493845200862 1.0 0.8586776517206077 7 Q8WUX9,Q92783 2 +Rho gtpase effectors 0.3102670319938287 0.7771899868270253 0.4370466889666802 1.0 0.8622561579693809 101 P68371,Q9UQB8,P04350,P84095,Q53HL2,P62805,Q99661,O43237,Q9BZD4,Q2NKX8,Q9HBM1,Q04917,P50748,Q16539,O43663,O75116,Q9NSV4,O00139,Q9Y3B8 19 +Cohesin loading onto chromatin 0.5206833249645677 0.777005333116321 0.4371556238711578 1.0 0.8622561579693809 8 Q7Z5K2 1 +Activated pkn1 stimulates transcription of ar androgen receptor regulated genes klk2 and klk3 0.6962802455760126 0.7740819962141132 0.4388823034679829 1.0 0.8631563681808812 3 P16104,P62805 2 +Flt3 signaling 0.5637712693532175 0.7547140657873813 0.4504205650002002 1.0 0.8718156089103438 5 P31749 1 +Gaba b receptor activation 0.5633047763492935 0.752941374903115 0.4514851437071618 1.0 0.8718156089103438 5 P04899 1 +G alpha z signalling events 0.5633047763492935 0.752941374903115 0.4514851437071618 1.0 0.8718156089103438 5 P04899 1 +Adp signalling through p2y purinoceptor 12 0.5633047763492935 0.752941374903115 0.4514851437071618 1.0 0.8718156089103438 5 P04899 1 +Darpp 32 events 0.5141809927516253 0.7495985887313682 0.4534965010601754 1.0 0.8718156089103438 8 P17612,Q08209,Q14738,P10644 4 +Sumo is conjugated to e1 uba2 sae1 0.5646209386281537 0.7495107850632066 0.4535494006619669 1.0 0.8718156089103438 2 Q9UBT2 1 +Sumo is transferred from e1 to e2 ube2i ubc9 0.5646209386281537 0.7495107850632066 0.4535494006619669 1.0 0.8718156089103438 2 Q9UBT2 1 +Processing and activation of sumo 0.5646209386281537 0.7495107850632066 0.4535494006619669 1.0 0.8718156089103438 2 Q9UBT2 1 +Tbc rabgaps 0.4526657509691095 0.7418018966960767 0.4582073712406305 1.0 0.8782846509393749 12 P20339,P60520 2 +Ctla4 inhibitory signaling 0.5459386328198741 0.7371676950125335 0.4610203762430473 1.0 0.8817245499761668 6 P31749 1 +Transcriptional regulation by runx1 0.3301346704525393 0.7367085619275222 0.4612995989941535 1.0 0.8817245499761668 62 P55036,O00487,Q03164,P49721,Q96ST3,Q13951 6 +Deactivation of the beta catenin transactivating complex 0.5107629241094616 0.7352688643266415 0.4621757664970209 1.0 0.8819449928897475 8 P31749 1 +S phase 0.3026078799983689 0.7310419401260433 0.4647535359461172 1.0 0.8819449928897475 89 P18858,P55036,O75832,Q7Z5K2,O00487,Q9NTI5,P31749,Q9BRX5,P49721,Q16763,P28072,P31751,P35244,Q9UBD5,Q07864 15 +Vitamin d calciferol metabolism 0.5595667870036047 0.7278856430134661 0.4666835924560044 1.0 0.8819449928897475 2 P38435 1 +Regulation of lipid metabolism by pparalpha 0.4117263513645915 0.7246889889216163 0.4686428517292484 1.0 0.8821130685596241 16 O75448,Q15067,Q96ST3,Q71SY5,P23786 5 +Apoptotic cleavage of cell adhesion proteins 0.554637491501971 0.720163546884227 0.4714243052584876 1.0 0.8848972801744265 5 P42574 1 +Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation 0.6626848905181554 0.7161655670014675 0.4738891217612897 1.0 0.887885428396247 4 P31749 1 +Metabolism of cofactors 0.5524640571209054 0.7119932832495506 0.476468935307502 1.0 0.8882322127337383 5 P31749 1 +Biological oxidations 0.3401179558753867 0.7088540375579202 0.4784150600832768 1.0 0.8889270103946518 43 O43169,Q8TB61,O75223,P22570,Q9NUJ1,Q16850 6 +Late endosomal microautophagy 0.5201902480195988 0.7032227306917482 0.4819169556956546 1.0 0.8924604640545793 7 Q8WUX9 1 +Met activates ras signaling 0.6572441878417744 0.6977086469050718 0.4853594194380879 1.0 0.8925621799950764 4 Q9NWH9 1 +Runx3 regulates p14 arf 0.6682643587118995 0.6786836650593852 0.4973383184196167 1.0 0.9089388899931138 3 Q13951 1 +The role of nef in hiv 1 replication and disease pathogenesis 0.4544987410483362 0.6782567299181992 0.4976089287379519 1.0 0.9089388899931138 11 Q10567 1 +Apc c cdc20 mediated degradation of cyclin b 0.4953936819240295 0.671569636614517 0.501857713596185 1.0 0.9105277261019658 8 P14635 1 +Creb1 phosphorylation through the activation of adenylate cyclase 0.665583243048026 0.6697236790838118 0.5030339539711708 1.0 0.9105277261019658 3 P17612,P10644 2 +Pka mediated phosphorylation of creb 0.665583243048026 0.6697236790838118 0.5030339539711708 1.0 0.9105277261019658 3 P17612,P10644 2 +Pka activation in glucagon signalling 0.665583243048026 0.6697236790838118 0.5030339539711708 1.0 0.9105277261019658 3 P17612,P10644 2 +Tnfr1 induced nfkappab signaling pathway 0.6460227900894839 0.6600319513413017 0.5092333255010566 1.0 0.916619985901902 4 O43318 1 +Dual incision in gg ner 0.383058002541398 0.6586752554841754 0.5101043259764761 1.0 0.9169732526481892 20 P35244,Q07864 2 +Displacement of dna glycosylase by apex1 0.6609839477655999 0.6544297929221687 0.5128349451629348 1.0 0.920264755144943 3 P13051 1 +Mitochondrial calcium ion transport 0.3999878237173994 0.6464264913737083 0.5180031886183869 1.0 0.9203978058228484 15 Q96TA2,Q8NE86 2 +Butyrate response factor 1 brf1 binds and destabilizes mrna 0.4475214436459594 0.6462696722991997 0.518104725132067 1.0 0.9203978058228484 11 P31749 1 +Clec7a dectin 1 signaling 0.3310675142875303 0.6424740214749095 0.5205654516753322 1.0 0.9211832106685824 49 P55036,O75832,O43318,O00487,Q15750,P49721,P28072,Q8TBC4,Q08209,P61088,Q14997 11 +Prc2 methylates histones and dna 0.6385778220225207 0.6353467912763378 0.5252022625971469 1.0 0.9232320977393424 4 P62805 1 +Signaling by ptk6 0.3990582615849354 0.6287553418576614 0.5295092408264794 1.0 0.9245807923834408 14 P20936,Q96JJ3,P31749 3 +Negative regulation of notch4 signaling 0.3288164179807913 0.6156241879191469 0.538142583504861 1.0 0.9302438680447171 41 P55036,O75832,O00487,P31749,P49721 5 +Anti inflammatory response favouring leishmania parasite infection 0.4112354699046876 0.6136533687777421 0.5394444088572992 1.0 0.9302438680447171 13 P04899,Q9Y3E5 2 +Processing of smdt1 0.4515850004327804 0.6019449508390202 0.5472107814005562 1.0 0.9309118565045384 10 Q8NE86 1 +Signaling by met 0.3937229633774616 0.6013484846703981 0.5476079027002694 1.0 0.9309118565045384 14 Q92783,P40763,Q9NWH9 3 +Adrenaline noradrenaline inhibits insulin secretion 0.6275732005066089 0.5993549952807643 0.5489361815430014 1.0 0.9309118565045384 4 P04899 1 +Unblocking of nmda receptors glutamate binding and activation 0.6270565304755306 0.5976804949421944 0.5500531425850952 1.0 0.9309118565045384 4 P07196 1 +Long term potentiation 0.6270565304755306 0.5976804949421944 0.5500531425850952 1.0 0.9309118565045384 4 P07196 1 +Ras activation upon ca2 influx through nmda receptor 0.6270565304755306 0.5976804949421944 0.5500531425850952 1.0 0.9309118565045384 4 P07196 1 +Recognition of dna damage by pcna containing replication complex 0.3833577648395432 0.5901774573739662 0.5550716836273182 1.0 0.9335921015464425 17 P35244 1 +Termination of translesion dna synthesis 0.3828523997973366 0.5874718455466866 0.5568868539110798 1.0 0.934454717688996 17 P35244 1 +Regulation of mecp2 expression and activity 0.4901947897439078 0.5859396834893646 0.5579160485613044 1.0 0.934454717688996 7 Q96ST3 1 +Transcriptional regulation of white adipocyte differentiation 0.4731108907087068 0.5817434264649036 0.5607395157418789 1.0 0.934454717688996 8 Q71SY5 1 +Signal amplification 0.4730522780939615 0.5815116934817838 0.5608956395150804 1.0 0.934454717688996 8 P63218,P04899 2 +Triglyceride catabolism 0.5047645784327706 0.5810978034648016 0.5611745389633513 1.0 0.934454717688996 6 P17612,Q01469,P62136 3 +Triglyceride metabolism 0.5047645784327706 0.5810978034648016 0.5611745389633513 1.0 0.934454717688996 6 P17612,Q01469,P62136 3 +Diseases of signal transduction by growth factor receptors and second messengers 0.2899209646944728 0.5792685309994627 0.5624079957570525 1.0 0.934454717688996 132 O75832,P19388,P36507,Q8IWJ2,Q96PU8,P49721,P26038,O95429,P55036,O00487,P31749,P49589,P28072,Q9NWH9,P31751,P56545,Q14789,P51608,Q16630 19 +Translation 0.281297283210911 0.5779929239549465 0.5632688965721828 1.0 0.934454717688996 209 P54577,P62906,Q5ST30,Q96DV4,P67812,Q5JTZ9,Q9Y3D9,P18077,P08240,Q6P1L8,P11940,P52815,P62249,P62910,Q9Y3U8,P62899,P62753,Q9Y2R5,P62424,P82664,P62841,O75616,Q9NRX2,P32969,P62263,P62081,P15880,P46199,P43307,Q96E11,P30050,P62861,Q96EY7,Q9BRJ2,P04844,P82673,P62241,Q5JPH6,Q13084,P04843,Q8N5N7,Q9BW92,P35268,P62244,P82675,P62269,Q9BYD2,P49589,P39019,P62750,Q04637,P61247,Q8TAE8,Q14197,P08865,Q15070,Q9NQ50,Q7L2H7,O60841,P05388,P61353,P42766,Q9Y2Z4,P18124,Q14152,Q9Y2Q9,P05387,O75822,O00303 69 +Myoclonic epilepsy of lafora 0.5231046931407883 0.5772666371269017 0.5637593476662643 1.0 0.934454717688996 2 P13807 1 +Meiotic recombination 0.4457303522689518 0.5768929035451412 0.564011804759917 1.0 0.934454717688996 10 P35244,P62805 2 +Regulation of runx2 expression and activity 0.3227104092163326 0.5649814250399879 0.5720863984862101 1.0 0.9433605531415112 42 P55036,O75832,O00487,P49721,Q13951,Q9UNE7 6 +Mitotic telophase cytokinesis 0.4289195657823861 0.5628968739939914 0.5735051089686951 1.0 0.9435755969593904 11 Q7Z5K2,Q9NTI5 2 +Translesion synthesis by y family dna polymerases bypasses lesions on dna template 0.3655101849537751 0.5571898491964195 0.5773977243612964 1.0 0.9465422284764798 20 P35244 1 +Phosphorylation of the apc c 0.4522893460905032 0.5496330183544671 0.5825711071756117 1.0 0.952724590435206 9 P14635 1 +Clathrin mediated endocytosis 0.3206527339241319 0.5482669191402787 0.5835086385540373 1.0 0.953110865138145 46 Q01968,O94973,P20645,Q8NC96,Q92783,P20339 6 +Lysosome vesicle biogenesis 0.3971201952846475 0.5454610089088576 0.5854364903219211 1.0 0.95388808619614 13 P20645 1 +Formation of the beta catenin tcf transactivating complex 0.4629342107110349 0.541909492861898 0.5878808568947487 1.0 0.9554365326461592 8 P16104,Q9Y265,P51532,P62805 4 +Tnf signaling 0.4769633493041203 0.5360850080672659 0.5918998008673846 1.0 0.9564706651352862 7 O95429,O43318,Q8TCT8 3 +Recognition and association of dna glycosylase with site containing an affected purine 0.6073288117431466 0.5348615294227516 0.5927456121126813 1.0 0.9566998656308005 4 P29372,P62805 2 +Class i peroxisomal membrane protein import 0.490317634406603 0.5287744170261575 0.5969619467285467 1.0 0.9612219023745202 6 P51648 1 +Egfr downregulation 0.4893174313390589 0.5252080670270293 0.599438557605211 1.0 0.96292789572752 6 O14964,Q92783 2 +C type lectin receptors clrs 0.3162661118818035 0.5232709753368437 0.6007856961085154 1.0 0.9639524923394008 51 P55036,O75832,O43318,O00487,Q15750,P49721,P28072,Q8TBC4,Q08209,P61088,Q14997 11 +Separation of sister chromatids 0.2868852121276823 0.5170029326678208 0.6051541116178081 1.0 0.9675346325748247 94 P68371,P04350,O75832,Q14738,Q06323,Q14997,Q53HL2,P49721,Q99661,O43237,Q9BZD4,Q2NKX8,Q9NTI5,P55036,Q9HBM1,O00487,P50748,Q16763,P28072,P62333,Q7Z5K2,O00139 22 +Lipophagy 0.616106897797036 0.5110605356218505 0.609308668800228 1.0 0.9702483138272128 3 O60664,P54619 2 +Regulation of runx3 expression and activity 0.3147202417807966 0.5105969993745975 0.6096332774204543 1.0 0.9702483138272128 38 P55036,O75832,O00487,P49721,Q13951 5 +Formation of the cornified envelope 0.5979371852742241 0.5057809670292684 0.6130104212566878 1.0 0.9702483138272128 4 P14923 1 +Keratinization 0.5979371852742241 0.5057809670292684 0.6130104212566878 1.0 0.9702483138272128 4 P14923 1 +E3 ubiquitin ligases ubiquitinate target proteins 0.3695134551086435 0.502043119590586 0.6156371898891528 1.0 0.9702483138272128 16 Q9BUN8,Q14527 2 +Fceri mediated nf kb activation 0.3149172093332351 0.5013388508527103 0.6161326672795324 1.0 0.9702483138272128 45 P55036,O75832,O43318,O00487,Q15750,P49721,P28072,P61088,Q14997 9 +Assembly of the orc complex at the origin of replication 0.4663191426105304 0.4969775914006812 0.6192048536110231 1.0 0.9728316717426364 7 Q9UBD5,P16104,P52294,P62805 4 +Transport of inorganic cations anions and amino acids oligopeptides 0.4657261451033709 0.4948271364001649 0.6207221474403908 1.0 0.9740893745629228 7 Q9UBX3,Q70HW3 2 +Signaling by robo receptors 0.282563243246438 0.4932776566225834 0.6218164135660635 1.0 0.9746810911606464 134 O75832,Q8TEY7,Q01518,P62906,P18077,P11940,P62249,P62910,Q9Y3U8,Q06323,P62753,P62899,P62424,Q14997,P62841,P49721,P32969,P62263,P62081,P15880,P30050,P62861,P62241,P55036,P35268,O00487,P62244,P62269,P39019,P28072,P62750,Q04637,P61247,Q15369,P08865,O43242,P62333,P05388,P61353,P42766,P18124,P05387,P17612,Q13617 44 +Rhobtb3 atpase cycle 0.6056073829744855 0.4793022890106095 0.6317235939811663 1.0 0.987931374246726 3 O14964 1 +Rhob gtpase cycle 0.3586974913146665 0.4782335699176832 0.6324839717290331 1.0 0.9879835834250068 18 O75116,P14923,P02786,Q9NQW6,Q9NSV4,Q9H0H5,Q92974,O00161 8 +Opioid signalling 0.3639165397229467 0.4742119900810927 0.6353487440497909 1.0 0.9892350984046232 16 Q08209,P04899 2 +Beta catenin independent wnt signaling 0.3092554178478049 0.4726188519159806 0.6364851302695507 1.0 0.9892350984046232 53 P55036,O75832,O43318,O00487,P49721,Q08209,P63218,O94973 8 +Metabolism of steroids 0.3089803466178644 0.4638127490310226 0.6427819084170721 1.0 0.9892350984046232 39 Q16850,Q15392,P22570 3 +Interleukin 1 signaling 0.3098858665808313 0.4618534340192821 0.6441864292700497 1.0 0.9892350984046232 46 P55036,O75832,O43318,O00487,Q15750,P49721,P28072,P61088,Q14997 9 +Amino acids regulate mtorc1 0.3922512936835062 0.4612776909189306 0.6445993884735159 1.0 0.9892350984046232 12 P21281,P36543,P21283,Q6IAA8,P42345 5 +The role of gtse1 in g2 m progression after g2 checkpoint 0.308435964909187 0.4538513917206128 0.6499357914249408 1.0 0.9902631589413382 49 P68371,O75832,P04350,P55036,O00487,P49721,P28072,P62333,P14635,Q14997 10 +Aggrephagy 0.3590863198705105 0.4505891815217321 0.6522856652648654 1.0 0.9904538760837456 16 P68371,P04350,O43237,P61088 4 +Activation of ampk downstream of nmdars 0.4517888346640391 0.4452097979431173 0.6561681467149276 1.0 0.9940677527383294 7 P68371,P04350,P54619 3 +Costimulation by the cd28 family 0.3878278838555434 0.4422960283640255 0.6582750045717489 1.0 0.9940677527383294 12 P31749 1 +Downstream signaling events of b cell receptor bcr 0.306877942548549 0.4388310058799227 0.6607839920067957 1.0 0.9940677527383294 44 P55036,O75832,O43318,O00487,P49721,Q08209 6 +Metabolism of nitric oxide nos3 activation and regulation 0.4642372094363849 0.4384639150126014 0.6610500228510312 1.0 0.9940677527383294 6 P31749 1 +Auf1 hnrnp d0 binds and destabilizes mrna 0.3059844639047095 0.4343974054015945 0.6639998815515349 1.0 0.9940677527383294 42 P55036,O75832,O00487,P49721,P04792,P11940 6 +Interleukin 1 family signaling 0.3061222917411419 0.4340266016805819 0.664269123787391 1.0 0.9940677527383294 48 P55036,O75832,O43318,O00487,Q15750,P49721,P28072,P40763,P61088,Q14997 10 +Programmed cell death 0.2804202922131706 0.4262143984892102 0.6699516266210648 1.0 0.9940677527383294 98 O75832,P07305,P52294,Q14997,P16403,P49721,P55036,O00487,Q04917,P31749,P28072,P31751,P40763,P62333,Q8WUX9,P10412,Q9Y3B8,P42574,O15294,Q9UNE7,P15924 21 +Acyl chain remodeling of cl 0.5873958805172628 0.4261115898992907 0.6700265353262029 1.0 0.9940677527383294 3 Q6UWP7 1 +Enos activation 0.5705359861671176 0.42441292645382 0.6712646951793884 1.0 0.9948186703912636 4 P31749 1 +Pyroptosis 0.4448861419058505 0.421334184484549 0.6735110714311128 1.0 0.9970605077068434 7 Q8WUX9,P42574 2 +Signaling by notch4 0.303490082885254 0.4142016824564138 0.67872640976261 1.0 0.9989910470040624 43 P55036,O75832,O00487,P31749,P49721 5 +Regulation of ras by gaps 0.3019753943889482 0.4118136437373352 0.6804760202679787 1.0 0.9989910470040624 39 P55036,O75832,P20936,O00487,P49721,P28072,Q14997 7 +Dna damage bypass 0.3335218642658126 0.4084377613850656 0.6829523151262831 1.0 0.9989910470040624 23 P35244 1 +Intrinsic pathway for apoptosis 0.3339875208366399 0.4068349030989811 0.6841292498097948 1.0 0.9989910470040624 21 P31749,P31751,P40763,P42574,Q9Y3B8 5 +Transmission across chemical synapses 0.301529770806875 0.4032212294404855 0.6867854835015867 1.0 0.9989910470040624 41 P63218,O75915,P07196,Q9Y639,P35609,P04899,O94973,P49593,P54619 9 +Mitotic metaphase and anaphase 0.2790788763260819 0.4013763989030008 0.6881430228851364 1.0 0.9989910470040624 125 P68371,P04350,O75832,Q14738,Q06323,P14635,Q14997,Q53HL2,P49721,Q99661,O43237,P30260,Q9BZD4,Q2NKX8,Q5SRE5,Q9NTI5,P55036,Q9HBM1,O00487,P50748,Q16763,P28072,Q99986,P62333,Q8WUX9,Q7Z5K2,O43633,O00139,Q86XL3 29 +Post translational modification synthesis of gpi anchored proteins 0.4629597694872999 0.4002236775108658 0.6889917766539491 1.0 0.9989910470040624 5 Q92643 1 +Attenuation phase 0.3765682292556739 0.395231733726343 0.6926718750109626 1.0 0.9989910470040624 12 P04792 1 +Deposition of new cenpa containing nucleosomes at the centromere 0.4486699054435966 0.3875321473259258 0.6983622904470259 1.0 0.9989910470040624 6 O60264,P62805 2 +Tcf dependent signaling in response to wnt 0.2963460219250569 0.3862353880836861 0.6993223473948564 1.0 0.9989910470040624 57 P55036,O75832,O00487,P62805,P31749,P49721,P28072,P19784,Q14738,P31751,P62333,Q06323,Q14997 13 +Phospholipid metabolism 0.3047208731380998 0.3815795577715654 0.7027732494708361 1.0 0.9989910470040624 36 O95674,Q8NCC3,P35790,P20339 4 +Rhoq gtpase cycle 0.3380640550006099 0.3752979958860686 0.7074388564639877 1.0 0.9989910470040624 18 P14923,P02786,Q9NSV4,Q68EM7,Q6IAA8,Q15758,O00161 7 +Regulation of hmox1 expression and activity 0.2981591891478395 0.373608776964869 0.7086954030095314 1.0 0.9989910470040624 44 P55036,O75832,O00487,P49721,P28072,P09601,P62333,Q06323,Q14997 9 +Retrograde transport at the trans golgi network 0.3427255425454881 0.3735955551040969 0.7087052413882877 1.0 0.9989910470040624 16 P53365,P20645 2 +Apoptosis 0.2702553410868981 0.3723962146386486 0.7095978718720413 1.0 0.9989910470040624 87 P55036,O75832,O00487,P10412,Q04917,P16403,P31749,P49721,Q14997,P28072,P31751,P07305,P40763,P42574,Q9Y3B8,P52294,P15924 17 +Hdr through mmej alt nhej 0.4154431994028412 0.3689187027287278 0.7121883223920271 1.0 0.9989910470040624 8 Q9UGN5 1 +Raf activation 0.4044748071698844 0.3682663497150156 0.7126746411328868 1.0 0.9989910470040624 9 Q9UQ13,Q14738,P36507 3 +Pi metabolism 0.3573271094916311 0.3670306407928175 0.7135961625281844 1.0 0.9989910470040624 13 Q01968,Q10713,Q96T51,Q8N9F7,P20339 5 +Dna strand elongation 0.3180383507143224 0.3613999704105584 0.717800470114293 1.0 0.9989910470040624 29 P18858 1 +Nicotinamide salvaging 0.5636181844657819 0.3606839195906323 0.7183357469846641 1.0 0.9989910470040624 3 P43490 1 +Glutamate and glutamine metabolism 0.4259761878171165 0.3585584279158126 0.7199254511528148 1.0 0.9989910470040624 7 P32322 1 +Detoxification of reactive oxygen species 0.4006895872419443 0.3550705345486234 0.7225367502926892 1.0 0.9989910470040624 9 P04179,Q16881 2 +Mitotic spindle checkpoint 0.2949371205619847 0.3493202982245922 0.7268488613499395 1.0 0.9989910470040624 45 Q9HBM1,Q53HL2,P50748,Q16763,O43237,Q9BZD4,Q2NKX8,O00139 8 +Mitotic prometaphase 0.2768982436421168 0.3485500838685326 0.7274271074764633 1.0 0.9989910470040624 78 P68371,Q9HBM1,P04350,Q53HL2,Q7Z5K2,P50748,Q99661,Q14738,O43237,Q9BZD4,Q9BSJ2,Q96CW5,Q2NKX8,Q9BPX3,O00139,P14635,Q9NTI5 17 +Slc mediated transmembrane transport 0.3348800033567036 0.3482433748270895 0.7276574155939957 1.0 0.9989910470040624 17 Q8TB61,Q8TAD4,Q70HW3,Q99808,Q9UBX3 5 +Inactivation of cdc42 and rac1 0.4599277978339282 0.3477274044214619 0.7280449137663634 1.0 0.9989910470040624 2 P60953 1 +Chaperone mediated autophagy 0.4352856109905871 0.3457799964135556 0.7295080594643941 1.0 0.9989910470040624 6 P11142,O60664,P07900,P08670,P08238 5 +Synthesis of pips at the golgi membrane 0.4341811073695745 0.3424245212680577 0.7320314373506347 1.0 0.9989910470040624 6 Q10713,Q01968 2 +Early phase of hiv life cycle 0.4070404646659995 0.3409821309147792 0.7331170339468926 1.0 0.9989910470040624 8 P18858 1 +Rna polymerase ii transcription 0.2679421528439196 0.3375261354776832 0.7357203135974368 1.0 0.9989910470040624 256 O75832,Q9UHY1,Q03164,P19388,Q86U42,Q6IAA8,Q71SY5,Q9UER7,P82979,Q06323,P14635,Q16881,Q14997,A5YKK6,O75448,Q14004,P62805,P49721,Q96ST3,Q13451,P19784,Q14241,P30260,Q86YP4,P35244,P18074,P55036,P13073,O00148,O00487,P42771,Q04917,P31749,Q16539,P15954,P16104,Q16763,P28072,Q9NWH9,P31751,Q15369,Q92797,Q8WYQ5,P62333,Q96KQ7,Q92989,P09669,Q9NQG5,P04179,Q13951,Q9H814,Q8WX92,P51608,Q9Y3B8,Q9UNE7,P35659,P54619 57 +Hsf1 dependent transactivation 0.3369174340037144 0.3335871900941023 0.7386910859044562 1.0 0.9989910470040624 14 O75190,P04792,Q96B36,P42345,P08238 5 +Ercc6 csb and ehmt2 g9a positively regulate rrna expression 0.3725001536300479 0.3334470523626586 0.7387968506817935 1.0 0.9989910470040624 11 P16104,Q86YP4,Q96KQ7,P62805 4 +Vesicle mediated transport 0.2670757598293086 0.3322558044379952 0.7396961089444325 1.0 0.9989910470040624 215 P68371,Q02241,Q15102,P68402,O00461,Q8WTV0,Q8IWJ2,Q92783,Q12756,Q99661,O43237,P20645,Q5JRA6,Q96A65,O15498,Q96KP1,Q01968,Q04917,P31749,Q14671,Q10567,P31751,Q7Z392,Q9H0H5,Q8NC96,P60520,P53365,O95721,O94973,P20339,Q9Y3P9,O15260,Q8WUX9,O43633,Q14789,Q9NVZ3,Q8TAG9,Q8IUR0,O00161,O00139,Q9Y3B8,P54619 42 +Ptk6 regulates rho gtpases ras gtpase and map kinases 0.4306807415523954 0.3318845883231612 0.7399764081845936 1.0 0.9989910470040624 6 P20936 1 +Dissolution of fibrin clot 0.5511014806789447 0.3282593352315907 0.7427155879329561 1.0 0.9989910470040624 3 P07355,P35237 2 +Negative feedback regulation of mapk pathway 0.5346849744560362 0.327066846836654 0.7436173264042234 1.0 0.9989910470040624 4 P36507 1 +Glycerophospholipid biosynthesis 0.3174472032582456 0.3267610653055671 0.743848609659536 1.0 0.9989910470040624 24 Q8NCC3,P35790 2 +Regulation of pten stability and activity 0.2910109160338303 0.3224663571286262 0.7470994207690296 1.0 0.9993342211236552 44 P55036,O00487,P31749,P49721,P31751,Q9UNE7 6 +G alpha 12 13 signalling events 0.4009271848622759 0.3212447834632984 0.748024896846726 1.0 0.9993342211236552 8 O75116,P63218,Q92974,Q14155 4 +Signal transduction by l1 0.4006966101704564 0.3205103519067403 0.748581484255983 1.0 0.9993342211236552 8 P19784,P36507 2 +Fc epsilon receptor fceri signaling 0.2894377448921386 0.3165912238828265 0.7515537958253049 1.0 1.0 53 P55036,O75832,O43318,O00487,Q15750,P49721,P28072,Q08209,P61088,Q14997 10 +Apc c mediated degradation of cell cycle proteins 0.290010041464907 0.3149742484296012 0.7527812062215675 1.0 1.0 50 P55036,O00487,P49721,Q16763,P14635 5 +Transcriptional regulation by runx3 0.2889772985883607 0.3119164211657872 0.755104042392085 1.0 1.0 42 P55036,O75832,O00487,P49721,Q13951 5 +Maturation of sars cov 2 spike protein 0.3874464894104308 0.3104883900463648 0.7561895869502164 1.0 1.0 9 P04843,P04844 2 +Dna replication initiation 0.4229756965336069 0.3092008876664894 0.7571687187062988 1.0 1.0 6 Q14181,P49642,Q07864 3 +Activation of the pre replicative complex 0.3202790679227678 0.3052952613101876 0.7601412847010611 1.0 1.0 19 P35244 1 +Budding and maturation of hiv virion 0.4206060406557869 0.3023713230408572 0.7623690131181251 1.0 1.0 6 Q8WUX9 1 +Nuclear events stimulated by alk signaling in cancer 0.3523896976090227 0.3010467972638671 0.7633788096870282 1.0 1.0 12 P51608,P40763 2 +Mapk family signaling cascades 0.2632004187827508 0.293922229328267 0.7688173314294842 1.0 1.0 88 P55036,O75832,P20936,O75608,O00487,P49356,P49721,P28072,Q14738,Q9NWH9,P07196,Q96S59,P04792,Q9UQ13,P36507,P35609,P62333,Q14997 18 +Transport of vitamins nucleosides and related molecules 0.4046164354855612 0.2928354308874272 0.7696479448397293 1.0 1.0 7 Q8TB61,Q99808 2 +Semaphorin interactions 0.3243556155980923 0.2873539294845648 0.7738413331835838 1.0 1.0 15 Q9NWH9 1 +Rhod gtpase cycle 0.3061976268077885 0.2740685947714726 0.7840319078427445 1.0 1.0 25 O15173,Q02952,Q9NSV4,Q8NHP6,Q68EM7,Q9H0H5,Q9BX68,O60610,P42166,Q9P2R3,Q5JTV8 11 +Rho gtpases activate pkns 0.3175098371783442 0.2726998229437942 0.7850839708169302 1.0 1.0 17 Q9Y3B8,Q04917,P62805 3 +Cdt1 association with the cdc6 orc origin complex 0.2816402409845506 0.2717346538401297 0.7858260536129857 1.0 1.0 39 P55036,O75832,O00487,P49721,P28072,Q9UBD5,Q14997 7 +Dectin 1 mediated noncanonical nf kb signaling 0.2825421155099401 0.2688746141918039 0.7880261727710036 1.0 1.0 42 P55036,O75832,O00487,P49721,P28072,Q8TBC4,Q14997 7 +Tnfr2 non canonical nf kb pathway 0.2825421155099399 0.268874614191803 0.7880261727710043 1.0 1.0 42 P55036,O75832,O00487,P49721,P28072,Q8TBC4,Q14997 7 +Nicotinate metabolism 0.5084788345188804 0.2635525855938868 0.7921246981957253 1.0 1.0 4 P43490,Q9BQG2 2 +Rhoa gtpase cycle 0.280041947494466 0.2552792530016695 0.7985074229216995 1.0 1.0 41 Q8NBN3,O15173,P14923,P30519,Q9NQW6,P52565,Q9NSV4,Q9H0H5,O00161,Q96HY6,O15498 11 +Diseases of immune system 0.4263537906137111 0.2481635314295574 0.8040078815937239 1.0 1.0 2 P09429 1 +Regulated necrosis 0.3110165454808744 0.2463488752844159 0.8054121784249959 1.0 1.0 17 Q8WUX9,O15294,Q9UNE7,P42574 4 +Telomere c strand synthesis initiation 0.4085074566478838 0.2461650196288786 0.8055544927792104 1.0 1.0 5 Q14181,P49642,P09884 3 +Degradation of cysteine and homocysteine 0.5003571370577965 0.2453139675120226 0.8062133376054494 1.0 1.0 4 Q96SZ5 1 +N glycan trimming in the er and calnexin calreticulin cycle 0.3126146462155315 0.241456303147934 0.8092014796822926 1.0 1.0 15 Q9BUN8,Q9NYU2 2 +Gap junction assembly 0.4062984298125314 0.240680915228948 0.8098024316623931 1.0 1.0 5 P68371,P04350 2 +Transport of connexons to the plasma membrane 0.4062984298125314 0.240680915228948 0.8098024316623931 1.0 1.0 5 P68371,P04350 2 +Rhoh gtpase cycle 0.3122875663781098 0.24022601191397 0.8101550494116705 1.0 1.0 15 O75116,P14923,P02786,P52565,Q6IAA8,Q15758 6 +Uptake and function of diphtheria toxin 0.4923138104048294 0.2279579690581652 0.8196789160851385 1.0 1.0 4 Q16881,P08238 2 +Fbxw7 mutants and notch1 in cancer 0.4176895306859151 0.2254913341558531 0.8215970661373149 1.0 1.0 2 Q13616 1 +Regulation of bach1 activity 0.4176895306859151 0.2254913341558531 0.8215970661373149 1.0 1.0 2 Q13616 1 +Degradation of dvl 0.271996400260584 0.2156612920927147 0.8292517756061608 1.0 1.0 38 P55036,O75832,O00487,P49721,P28072,Q14997 6 +Abc transporter disorders 0.273350870267564 0.2110013479006844 0.832886219562081 1.0 1.0 42 P55036,O75832,O00487,P49721,Q9BUN8 5 +Defective cftr causes cystic fibrosis 0.2733508702675639 0.2110013479006836 0.8328862195620816 1.0 1.0 42 P55036,O75832,O00487,P49721,Q9BUN8 5 +Asymmetric localization of pcp proteins 0.271184833548044 0.2108538047287458 0.8330013521323456 1.0 1.0 38 P55036,O75832,O00487,P49721,P28072,Q14997 6 +Cross presentation of soluble exogenous antigens endosomes 0.2732819209502541 0.2047730121690532 0.8377494733636561 1.0 1.0 37 P55036,O75832,O00487,P49721,P28072,Q14997 6 +Degradation of axin 0.2732819209502541 0.2047730121690532 0.8377494733636561 1.0 1.0 37 P55036,O75832,O00487,P49721,P28072,Q14997 6 +M phase 0.2477671711266579 0.2025122556607031 0.8395162782697014 1.0 1.0 171 P68371,P04350,O75832,Q02241,P62820,Q14738,Q06323,P14635,Q14997,Q53HL2,P62805,P49721,Q99661,P19784,O43237,P30260,Q9BZD4,Q2NKX8,Q5SRE5,Q9NTI5,P55036,Q9HBM1,O00487,P50748,O43768,Q16763,P28072,Q99986,Q9BPX3,P62333,Q8WUX9,P42695,Q7Z5K2,O43633,Q9BSJ2,Q96CW5,O00139,Q86XL3 38 +Uptake and actions of bacterial toxins 0.3579769213184767 0.1982194959876453 0.842873334522811 1.0 1.0 8 Q02750,Q16881,P36507,P08238 4 +Transferrin endocytosis and recycling 0.3312006817075494 0.1972599988193962 0.8436240805918538 1.0 1.0 11 P21281,P21283,P02786 3 +Alk mutants bind tkis 0.3767172812725896 0.1895227439236787 0.8496831310338577 1.0 1.0 6 Q9HC35,O43815,Q00610,Q9NR09,P10644 5 +Inhibition of replication initiation of damaged dna by rb1 e2f1 0.3742947936461769 0.184098208981835 0.8539364114922865 1.0 1.0 6 Q14181,P49642,P49643,P09884 4 +Apoptotic execution phase 0.2839853817585662 0.1829006201177448 0.8548759963214336 1.0 1.0 28 P10412,P16403,P07305,P42574,P15924 5 +G2 m dna damage checkpoint 0.2796933643591699 0.180120766457107 0.8570577599558629 1.0 1.0 32 P35244,P14635 2 +Gene silencing by rna 0.2680662136576169 0.1752053529105575 0.8609182783782159 1.0 1.0 44 P19388 1 +Intra golgi traffic 0.3404511894412754 0.1749576070431078 0.8611129443988137 1.0 1.0 9 O95721,O00461 2 +Potential therapeutics for sars 0.2804135246456756 0.1725488955068604 0.8630060246955 1.0 1.0 30 O94973,P49356 2 +Signaling by the b cell receptor bcr 0.2680726143904533 0.1707584699251667 0.8644136855679045 1.0 1.0 47 P55036,O75832,O43318,O00487,P49721,Q08209 6 +Traf6 mediated nf kb activation 0.4599326181319336 0.1654831447626396 0.8685637154607104 1.0 1.0 4 Q14258 1 +Rho gtpases activate formins 0.2666441553502822 0.16138662616574 0.8717888993746679 1.0 1.0 52 P68371,Q9HBM1,Q53HL2,P50748,Q9NSV4,Q9BZD4,O43237,Q2NKX8,O00139 9 +Dna replication pre initiation 0.2631310095154374 0.1607701617955913 0.8722744269260567 1.0 1.0 61 P55036,O75832,O00487,P49721,P28072,P35244,Q07864,Q9UBD5,P52294,Q14997 10 +Scf skp2 mediated degradation of p27 p21 0.2633826512953422 0.1593747202159444 0.8733736546728104 1.0 1.0 40 P55036,O75832,O00487,P49721 4 +Stabilization of p53 0.262846473684005 0.1564494672211621 0.8756787479798689 1.0 1.0 40 P55036,O75832,O00487,P49721,P28072,P62333,Q06323,Q14997 8 +Dna replication 0.2487490206664948 0.1520986614057433 0.8791091199685463 1.0 1.0 84 P18858,P55036,O75832,O00487,Q9BRX5,P49721,Q14997,Q16763,P28072,P35244,Q9UBD5,P52294,Q07864 13 +Metabolism of polyamines 0.2613473818591743 0.1517517479716963 0.8793827407908505 1.0 1.0 39 P55036,O75832,O00487,P49721,P28072,Q14997 6 +Assembly and cell surface presentation of nmda receptors 0.3183398651837327 0.1412595495924999 0.8876649038707769 1.0 1.0 10 P68371,P04350,P35609,P07196 4 +Synthesis of ketone bodies 0.4569470934319683 0.137051959747453 0.8909897246190253 1.0 1.0 3 P35610 1 +Ketone body metabolism 0.4569470934319683 0.137051959747453 0.8909897246190253 1.0 1.0 3 P35610 1 +Tp53 regulates transcription of genes involved in cytochrome c release 0.3758122743682252 0.1347137478754213 0.8928382030460225 1.0 1.0 2 Q07812 1 +Pi5p regulates tp53 acetylation 0.3758122743682252 0.1347137478754213 0.8928382030460225 1.0 1.0 2 Q13526 1 +Nervous system development 0.2508582307855885 0.1334998760143148 0.8937980623195343 1.0 1.0 201 P68371,P04350,Q00169,Q8TEY7,Q01518,O75832,P62906,P18077,P11940,P36507,Q16850,P62249,P62910,Q9Y3U8,Q06323,P62753,P62899,P62424,P50570,Q14997,P62841,O15145,O95239,P49721,P32969,P19784,P62263,P62081,P35241,P15880,Q92542,P26038,P30050,P62861,Q02750,P62241,P55036,P20936,P35268,O00487,P62244,P62269,Q16539,P39019,P28072,P62750,Q04637,Q9NWH9,P61247,Q15369,P08865,O43242,O94973,P05388,P62333,P08238,O75116,Q14195,P61353,P42766,Q9Y490,P18124,Q96S59,Q13885,P05387,P17612,Q13617 67 +Hdacs deacetylate histones 0.3134827916889274 0.1302518612122804 0.8963671647078106 1.0 1.0 10 Q86YP4 1 +Caspase mediated cleavage of cytoskeletal proteins 0.3365825789521353 0.1279167886273687 0.8982148247911865 1.0 1.0 7 P42574 1 +Synthesis of diphthamide eef2 0.3714801444043262 0.1271256005239646 0.898840989555481 1.0 1.0 2 Q9BQC3 1 +Uch proteinases 0.2588335144404655 0.1243063980472364 0.901072681685597 1.0 1.0 44 P55036,O75832,O00487,P49721,P28072,O15294,Q14997 7 +Pten regulation 0.2572186751889894 0.1234926776668473 0.9017169722854944 1.0 1.0 61 P55036,O75832,O00487,P31749,P49721,P28072,P31751,Q6IAA8,Q86YP4,Q9UNE7 10 +Synthesis of dna 0.2493933871751248 0.122157308554673 0.9027744360085024 1.0 1.0 79 P18858,P55036,O75832,O00487,Q9BRX5,P49721,Q16763,P28072,P35244,Q9UBD5,Q07864 11 +Degradation of gli1 by the proteasome 0.2563730598439753 0.1193600849338786 0.9049900827775386 1.0 1.0 41 P55036,O75832,O00487,P49721,P28072,Q14997 6 +Rho gtpases activate nadph oxidases 0.3444163353812708 0.1150089758839493 0.908438007529468 1.0 1.0 5 Q16539,P63000,P27361,Q13526 4 +G alpha i signalling events 0.2692319153930856 0.1138319600434804 0.909371002802256 1.0 1.0 20 Q08209,P04899 2 +Membrane trafficking 0.2508046603097769 0.1130277015501702 0.9100085932744252 1.0 1.0 209 P68371,Q02241,Q15102,P68402,O00461,Q8IWJ2,Q92783,Q12756,Q99661,O43237,P20645,Q5JRA6,Q96A65,O15498,Q96KP1,Q01968,Q04917,P31749,Q14671,Q10567,P31751,Q7Z392,Q9H0H5,Q8NC96,P53365,P60520,O95721,O94973,P20339,Q9Y3P9,O15260,Q8WUX9,O43633,Q14789,Q9NVZ3,Q8TAG9,Q8IUR0,O00161,O00139,Q9Y3B8,P54619 41 +Miro gtpase cycle 0.4254491071364238 0.1123930678096875 0.9105117515889702 1.0 1.0 4 O95140 1 +Rhot1 gtpase cycle 0.3606498194945783 0.1096110053037523 0.9127178822832906 1.0 1.0 2 P52306 1 +Inositol phosphate metabolism 0.4198663286796295 0.1051024361554053 0.9162945262403506 1.0 1.0 4 Q01968 1 +Peroxisomal lipid metabolism 0.3003045984828557 0.1028353853089694 0.9180936207147656 1.0 1.0 10 P51648,O15254 2 +Map3k8 tpl2 dependent mapk1 3 activation 0.417991329479777 0.1027340427575649 0.9181740543690816 1.0 1.0 4 Q13616,Q02750,O15111 3 +Ros and rns production in phagocytes 0.306369273958484 0.1017982556647876 0.9189168102367492 1.0 1.0 9 P21281,P21283 2 +Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10 0.4265077645359301 0.0967933519583609 0.9228905035137492 1.0 1.0 3 Q7Z434,Q14258 2 +Tcr signaling 0.2545560256223413 0.0958451275677216 0.9236435756980552 1.0 1.0 48 P55036,O75832,O43318,O00487,P49721,P28072 6 +Cellular response to hypoxia 0.2505964005948339 0.094287658006052 0.9248806537214302 1.0 1.0 40 P55036,O75832,O00487,P49721,P28072,Q15369,P62333,Q06323,Q14997 9 +G1 s dna damage checkpoints 0.2511448836932289 0.0937796955903065 0.9252841611632056 1.0 1.0 41 P55036,O75832,O00487,P49721,P28072,P62333,Q06323,Q14997 8 +Pcp ce pathway 0.2536066443719645 0.0923819222200521 0.9263946019801332 1.0 1.0 47 P55036,O75832,O00487,P49721,O94973 5 +Signalling to erks 0.3009038835682777 0.0921354279802951 0.926590440695239 1.0 1.0 9 Q16539,P36507 2 +Protein ubiquitination 0.2620033815441125 0.0919654321334883 0.9267255043266976 1.0 1.0 24 Q9BUN8,Q16763,Q14527 3 +Erks are inactivated 0.3126622273504105 0.0878066418374112 0.9300303587353228 1.0 1.0 7 Q8IV63 1 +Regulation of pyruvate dehydrogenase pdh complex 0.3203181489515438 0.0866614560731387 0.9309406147054824 1.0 1.0 6 P11177,P10515,P09622,Q15120,O43708 5 +Sars cov infections 0.2520833120320783 0.0849200690472924 0.9323249366256604 1.0 1.0 47 P04843,Q8WUX9,O75116,P49356,Q86YP4,P04844,O94973 7 +Map2k and mapk activation 0.2840583657508905 0.0848643784039031 0.9323692115047596 1.0 1.0 11 Q9Y490,P36507 2 +Signaling by moderate kinase activity braf mutants 0.2840583657508905 0.0848643784039031 0.9323692115047596 1.0 1.0 11 Q9Y490,P36507 2 +Reproduction 0.2585723891735128 0.0834742389936838 0.9334744601946556 1.0 1.0 22 O94901,P35244 2 +Meiosis 0.2585723891735128 0.0834742389936838 0.9334744601946556 1.0 1.0 22 O94901,P35244 2 +Regulation of glycolysis by fructose 2 6 bisphosphate metabolism 0.399827917189079 0.0818386091719511 0.9347750533537982 1.0 1.0 4 Q14738 1 +Diseases associated with n glycosylation of proteins 0.4120621162874647 0.0812984827314349 0.935204580602686 1.0 1.0 3 Q9BT22,O75340 2 +Regulation of pten gene transcription 0.2600652883569041 0.0812683932232383 0.9352285093773304 1.0 1.0 15 P04637,Q8WXI9,Q15022,Q13547,O94776,Q13330,O60341,Q92769,P27361,Q6IAA8,Q86YP4,P42345,P28482,Q9Y2Q5 14 +Mapk6 mapk4 signaling 0.2515165701218955 0.0808409761079303 0.9355684204716423 1.0 1.0 48 P55036,O75832,O00487,P49721,P04792 5 +Degradation of beta catenin by the destruction complex 0.2512057480268493 0.080691728657906 0.9356871149415192 1.0 1.0 47 P55036,O75832,O00487,P56545,P49721,P28072,Q14738,P62333,Q14997 9 +Tp53 regulates transcription of cell death genes 0.3130874909616712 0.0770113037731237 0.9386145525645084 1.0 1.0 6 P04637,P49327,P55212,P42575,Q07812 5 +Signaling by alk in cancer 0.2541128666801893 0.0759725859736123 0.9394409083718545 1.0 1.0 33 P26038,P49589,Q8IWJ2,P51608 4 +Alpha linolenic omega3 and linoleic omega6 acid metabolism 0.3120731488701149 0.0757198145750882 0.9396420114973758 1.0 1.0 6 Q15067 1 +Hedgehog on state 0.2476789296868017 0.0749222531069135 0.9402765708973172 1.0 1.0 42 P55036,O75832,O00487,P49721,P28072,Q14997 6 +Insulin receptor recycling 0.2840089597008615 0.07386675344242 0.9411164104623246 1.0 1.0 10 P21281,P21283 2 +Cooperation of prefoldin and tric cct in actin and tubulin folding 0.2570289660774077 0.0738605408764424 0.9411213538691768 1.0 1.0 17 P68371,P04350,Q13885,O15212 4 +Intraflagellar transport 0.2802279566573373 0.0679125593287417 0.945855240938108 1.0 1.0 10 P68371,P04350,A0AVF1 3 +Signaling by insulin receptor 0.2538277732843547 0.0675238072160413 0.9461647098568522 1.0 1.0 15 P21281 1 +Hiv life cycle 0.244614133232924 0.0644027730374874 0.9486495220483082 1.0 1.0 67 P18858,Q14241,P17096,P19388 4 +Cell cycle mitotic 0.2489353330601813 0.0614111092396667 0.951031805166112 1.0 1.0 225 P68371,P04350,O75832,Q02241,P62820,Q14738,Q9UBD5,Q9Y248,Q06323,P14635,Q14997,P18858,Q53HL2,P62805,P49721,Q99661,P19784,O43237,P30260,Q9BZD4,Q2NKX8,P35244,Q9BVL2,Q5SRE5,Q9NTI5,P55036,Q9HBM1,O00487,P42771,P31749,P50748,O43768,P16104,Q16763,P28072,P31751,Q99640,Q99986,Q9BPX3,P62333,Q07864,Q8WUX9,P42695,Q7Z5K2,O43633,Q9BRX5,P00374,Q9BSJ2,Q96CW5,O00139,Q86XL3 51 +Copi independent golgi to er retrograde traffic 0.2503176997007098 0.0573739750395796 0.9542472937539104 1.0 1.0 27 P68371,P04350,Q9H2M9,Q9UJW0,P68402,Q15102,O43237,Q13885 8 +Cell cycle checkpoints 0.2460169844898237 0.0555079565584802 0.9557337913078308 1.0 1.0 127 O75832,Q9UBD5,P14635,Q14997,Q53HL2,P62805,P49721,O43237,Q9BZD4,Q2NKX8,P35244,P55036,Q9HBM1,O00487,P50748,Q16763,P28072,Q99640,P61088,O00139,Q9Y3B8 21 +Cooperation of pdcl phlp1 and tric cct in g protein beta folding 0.2586533340049338 0.0521990384234766 0.95837009911773 1.0 1.0 12 P63218 1 +Tfap2a acts as a transcriptional repressor during retinoic acid induced cell differentiation 0.376309136872517 0.0520680082112191 0.9584745041231616 1.0 1.0 3 P46087,P10809 2 +Tp53 regulates transcription of caspase activators and caspases 0.3759479956663009 0.0518336100573945 0.9586612745844764 1.0 1.0 3 P55212,P42575 2 +Gamma carboxylation hypusine formation and arylsulfatase activation 0.2731197876893737 0.0516260836695412 0.9588266352862038 1.0 1.0 9 Q9BU89,P49366,O43681,P38435,Q9BQC3 5 +Beta oxidation of hexanoyl coa to butanoyl coa 0.3622454364830925 0.0496395454625095 0.9604096327390328 1.0 1.0 4 P55084 1 +Beta oxidation of lauroyl coa to decanoyl coa coa 0.3622454364830925 0.0496395454625095 0.9604096327390328 1.0 1.0 4 P55084 1 +Slbp dependent processing of replication dependent histone pre mrnas 0.3701697363669162 0.0482347686738636 0.9615291410306102 1.0 1.0 3 P62304,P62318 2 +Platelet homeostasis 0.2660404189400996 0.0480606686412687 0.9616678918389778 1.0 1.0 10 Q16539,P63218 2 +Dna methylation 0.3578831240926597 0.0467786908648314 0.9626896126641724 1.0 1.0 4 P62805 1 +Scavenging by class f receptors 0.3572976878612746 0.0464074736226936 0.9629854798430252 1.0 1.0 4 P27797,Q92598,P07900 3 +Protein folding 0.2395466675649118 0.0444095692410784 0.9645779340243364 1.0 1.0 37 P68371,P04350,P61962,P19784,Q13885,P40763,Q99426,O95302,P63218,O15212 10 +Hiv infection 0.2448760120013293 0.0420706873266817 0.9664423475987196 1.0 1.0 122 P18858,P55036,Q8WUX9,O00487,P19388,P49721,Q10567,Q14241,O94973,P17096 10 +Response to elevated platelet cytosolic ca2 0.2437644395063476 0.0368375197320648 0.9706145579192632 1.0 1.0 30 P55145,O15439 2 +Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 0.2711462282523845 0.0362472493588911 0.9710852111825156 1.0 1.0 5 Q99808 1 +Sars cov 1 infection 0.2578138330425916 0.0351036130226081 0.9719971204140287 1.0 1.0 9 Q8WUX9 1 +Reduction of cytosolic ca levels 0.3387504514265066 0.0331965132261682 0.9735178786340926 1.0 1.0 3 P16615,P20020 2 +Platelet calcium homeostasis 0.3387504514265066 0.0331965132261682 0.9735178786340926 1.0 1.0 3 P16615,P20020 2 +Beta catenin phosphorylation cascade 0.2612246407793667 0.0305654911205691 0.9756160633797182 1.0 1.0 5 Q14738,P30153,P35222 3 +Disassembly of the destruction complex and recruitment of axin to the membrane 0.2612246407793667 0.0305654911205691 0.9756160633797182 1.0 1.0 5 Q14738,P30153,P35222 3 +Signaling by ctnnb1 phospho site mutants 0.2612246407793667 0.0305654911205691 0.9756160633797182 1.0 1.0 5 Q14738,P30153,P35222 3 +Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 0.2377007898269798 0.0281761517898649 0.9775216577859408 1.0 1.0 44 P55036,O75832,O00487,P49721,P28072,Q16763,P62333,Q06323,Q14997 9 +Sars cov 2 infection 0.2338012583581664 0.0270133694553566 0.9784490706398552 1.0 1.0 17 P04843,Q8WUX9,P04844 3 +Hdms demethylate histones 0.2452691510587693 0.0233457674254239 0.9813744645231604 1.0 1.0 5 O60341,P62805 2 +Intracellular signaling by second messengers 0.2343828337521619 0.023161123284568 0.981521749406658 1.0 1.0 79 P55036,O75832,O00487,P31749,P84095,P49721,P28072,Q14738,Q9NWH9,P31751,Q96B36,Q9UNE7,Q86YP4,Q6IAA8,P62333,Q06323,Q14997 17 +Protein methylation 0.2487346348517687 0.0222110705201434 0.9822795867718456 1.0 1.0 6 P55072,P11142,P15880,P13639,P38117 5 +Orc1 removal from chromatin 0.2380234877568566 0.0218368023003729 0.9825781371889732 1.0 1.0 48 P55036,O75832,O00487,P49721,P28072,Q9UBD5,Q14997 7 +Rho gtpases activate iqgaps 0.2362616179404335 0.0181680825075814 0.9855047649015154 1.0 1.0 10 P68371,P04350 2 +Sumoylation of transcription factors 0.2308526011560688 0.0139090523461309 0.9889025397011016 1.0 1.0 4 P04637,Q13330,P42771 3 +Regulation of mrna stability by proteins that bind au rich elements 0.2350634509637366 0.01178060258598 0.9906006564910792 1.0 1.0 63 P55036,O75832,Q06265,O00487,P31749,P49721,P04792,P11940 8 +Glycogen metabolism 0.221287563453989 0.0096387184747055 0.992309534423606 1.0 1.0 9 Q16851 1 +Intra golgi and retrograde golgi to er traffic 0.2276414835486331 0.0030371004084194 0.997576748199852 1.0 1.0 84 P68371,P04350,Q02241,P62820,Q15102,P68402,O00461,Q8IWJ2,Q12756,Q99661,O43237,P20645,O15498,Q9H0H5,P53365,O95721,O15260,P61923,O00139 19 +G2 m checkpoints 0.2293670717927085 0.0011295036347045 0.9990987866801232 1.0 1.0 81 P55036,O75832,O00487,Q04917,P62805,P49721,P28072,Q99640,P35244,P61088,Q9UBD5,Q9Y3B8,P14635,Q14997 14 diff --git a/msigdb_reactome/selections.json b/msigdb_reactome/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..6159206208e888a617993adab43eabe66e166d69 --- /dev/null +++ b/msigdb_reactome/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2 ltr circle formation", "Abacavir metabolism", "Abacavir transmembrane transport", "Abacavir transport and metabolism", "Abc family proteins mediated transport", "Abc transporter disorders", "Abc transporters in lipid homeostasis", "Aberrant regulation of mitotic exit in cancer due to rb1 defects", "Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects", "Abortive elongation of hiv 1 transcript in the absence of tat", "Acetylcholine regulates insulin secretion", "Activated notch1 transmits signal to the nucleus", "Activated ntrk2 signals through cdk5", "Activated ntrk2 signals through frs2 and frs3", "Activated ntrk2 signals through fyn", "Activated ntrk2 signals through pi3k", "Activated ntrk2 signals through ras", "Activated ntrk3 signals through ras", "Activated pkn1 stimulates transcription of ar androgen receptor regulated genes klk2 and klk3", "Activated tak1 mediates p38 mapk activation", "Activation of ampk downstream of nmdars", "Activation of anterior hox genes in hindbrain development during early embryogenesis", "Activation of atr in response to replication stress", "Activation of bad and translocation to mitochondria", "Activation of bh3 only proteins", "Activation of caspases through apoptosome mediated cleavage", "Activation of gene expression by srebf srebp", "Activation of irf3 irf7 mediated by tbk1 ikk epsilon", "Activation of kainate receptors upon glutamate binding", "Activation of nima kinases nek9 nek6 nek7", "Activation of nmda receptors and postsynaptic events", "Activation of noxa and translocation to mitochondria", "Activation of ppargc1a pgc 1alpha by phosphorylation", "Activation of puma and translocation to mitochondria", "Activation of rac1", "Activation of rac1 downstream of nmdars", "Activation of smo", "Activation of the ap 1 family of transcription factors", "Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s", "Activation of the pre replicative complex", "Acyl chain remodeling of cl", "Acyl chain remodelling of pc", "Acyl chain remodelling of pe", "Acyl chain remodelling of pg", "Acyl chain remodelling of ps", "Adaptive immune system", "Adenylate cyclase inhibitory pathway", "Adherens junctions interactions", "Adora2b mediated anti inflammatory cytokines production", "Adp signalling through p2y purinoceptor 1", "Adp signalling through p2y purinoceptor 12", "Adrenaline noradrenaline inhibits insulin secretion", "Advanced glycosylation endproduct receptor signaling", "Aflatoxin activation and detoxification", "Aggrephagy", "Akt phosphorylates targets in the cytosol", "Akt phosphorylates targets in the nucleus", "Alk mutants bind tkis", "Alpha linolenic omega3 and linoleic omega6 acid metabolism", "Alpha oxidation of phytanate", "Alpha protein kinase 1 signaling pathway", "Amino acid transport across the plasma membrane", "Amino acids regulate mtorc1", "Amyloid fiber formation", "Anchoring of the basal body to the plasma membrane", "Androgen biosynthesis", "Anti inflammatory response favouring leishmania parasite infection", "Antigen activates b cell receptor bcr leading to generation of second messengers", "Antigen presentation folding assembly and peptide loading of class i mhc", "Antigen processing cross presentation", "Antigen processing ubiquitination proteasome degradation", "Antimicrobial peptides", "Antiviral mechanism by ifn stimulated genes", "Apc c cdc20 mediated degradation of cyclin b", "Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1", "Apc c mediated degradation of cell cycle proteins", "Apc cdc20 mediated degradation of nek2a", "Apex1 independent resolution of ap sites via the single nucleotide replacement pathway", "Apobec3g mediated resistance to hiv 1 infection", "Apoptosis", "Apoptosis induced dna fragmentation", "Apoptotic cleavage of cell adhesion proteins", "Apoptotic cleavage of cellular proteins", "Apoptotic execution phase", "Apoptotic factor mediated response", "Aquaporin mediated transport", "Arachidonate production from dag", "Arachidonic acid metabolism", "Arms mediated activation", "Aryl hydrocarbon receptor signalling", "Asparagine n linked glycosylation", "Aspartate and asparagine metabolism", "Assembly and cell surface presentation of nmda receptors", "Assembly of collagen fibrils and other multimeric structures", "Assembly of the hiv virion", "Assembly of the orc complex at the origin of replication", "Association of tric cct with target proteins during biosynthesis", "Asymmetric localization of pcp proteins", "Atf4 activates genes in response to endoplasmic reticulum stress", "Atf6 atf6 alpha activates chaperone genes", "Atf6 atf6 alpha activates chaperones", "Attachment and entry", "Attachment of gpi anchor to upar", "Attenuation phase", "Auf1 hnrnp d0 binds and destabilizes mrna", "Aurka activation by tpx2", "Autophagy", "B wich complex positively regulates rrna expression", "Base excision repair", "Base excision repair ap site formation", "Basigin interactions", "Bbsome mediated cargo targeting to cilium", "Beta catenin independent wnt signaling", "Beta catenin phosphorylation cascade", "Beta oxidation of butanoyl coa to acetyl coa", "Beta oxidation of decanoyl coa to octanoyl coa coa", "Beta oxidation of hexanoyl coa to butanoyl coa", "Beta oxidation of lauroyl coa to decanoyl coa coa", "Beta oxidation of octanoyl coa to hexanoyl coa", "Beta oxidation of pristanoyl coa", "Beta oxidation of very long chain fatty acids", "Bh3 only proteins associate with and inactivate anti apoptotic bcl 2 members", "Bile acid and bile salt metabolism", "Binding and uptake of ligands by scavenger receptors", "Binding of tcf lef ctnnb1 to target gene promoters", "Biological oxidations", "Biosynthesis of epa derived spms", "Biosynthesis of maresins", "Biosynthesis of specialized proresolving mediators spms", "Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein", "Biotin transport and metabolism", "Bmal1 clock npas2 activates circadian gene expression", "Branched chain amino acid catabolism", "Budding and maturation of hiv virion", "Butyrate response factor 1 brf1 binds and destabilizes mrna", "C type lectin receptors clrs", "Ca dependent events", "Ca2 pathway", "Calcineurin activates nfat", "Calnexin calreticulin cycle", "Camk iv mediated phosphorylation of creb", "Carboxyterminal post translational modifications of tubulin", "Cardiac conduction", "Cargo concentration in the er", "Cargo recognition for clathrin mediated endocytosis", "Cargo trafficking to the periciliary membrane", "Carnitine metabolism", "Caspase activation via death receptors in the presence of ligand", "Caspase activation via dependence receptors in the absence of ligand", "Caspase activation via extrinsic apoptotic signalling pathway", "Caspase mediated cleavage of cytoskeletal proteins", "Cation coupled chloride cotransporters", "Cd163 mediating an anti inflammatory response", "Cd209 dc sign signaling", "Cd28 co stimulation", "Cd28 dependent pi3k akt signaling", "Cd28 dependent vav1 pathway", "Cdc42 gtpase cycle", "Cdc6 association with the orc origin complex", "Cdt1 association with the cdc6 orc origin complex", "Cell cell communication", "Cell cell junction organization", "Cell cycle", "Cell cycle checkpoints", "Cell cycle mitotic", "Cell death signalling via nrage nrif and nade", "Cell extracellular matrix interactions", "Cell junction organization", "Cell surface interactions at the vascular wall", "Cellular response to chemical stress", "Cellular response to heat stress", "Cellular response to hypoxia", "Cellular response to starvation", "Cellular responses to stimuli", "Cellular senescence", "Chaperone mediated autophagy", "Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex", "Chl1 interactions", "Cholesterol biosynthesis", "Choline catabolism", "Chondroitin sulfate dermatan sulfate metabolism", "Chrebp activates metabolic gene expression", "Chromatin modifying enzymes", "Chromosome maintenance", "Chylomicron assembly", "Cilium assembly", "Circadian clock", "Citric acid cycle tca cycle", "Class a 1 rhodopsin like receptors", "Class b 2 secretin family receptors", "Class i mhc mediated antigen processing presentation", "Class i peroxisomal membrane protein import", "Clathrin mediated endocytosis", "Clec7a dectin 1 induces nfat activation", "Clec7a dectin 1 signaling", "Cobalamin cbl vitamin b12 transport and metabolism", "Coenzyme a biosynthesis", "Cohesin loading onto chromatin", "Collagen biosynthesis and modifying enzymes", "Collagen degradation", "Collagen formation", "Competing endogenous rnas cernas regulate pten translation", "Complement cascade", "Complex i biogenesis", "Condensation of prometaphase chromosomes", "Condensation of prophase chromosomes", "Constitutive signaling by aberrant pi3k in cancer", "Constitutive signaling by akt1 e17k in cancer", "Constitutive signaling by egfrviii", "Constitutive signaling by ligand responsive egfr cancer variants", "Constitutive signaling by overexpressed erbb2", "Conversion from apc c cdc20 to apc c cdh1 in late anaphase", "Cooperation of pdcl phlp1 and tric cct in g protein beta folding", "Cooperation of prefoldin and tric cct in actin and tubulin folding", "Copi dependent golgi to er retrograde traffic", "Copi independent golgi to er retrograde traffic", "Copi mediated anterograde transport", "Copii mediated vesicle transport", "Costimulation by the cd28 family", "Creatine metabolism", "Creb phosphorylation", "Creb1 phosphorylation through nmda receptor mediated activation of ras signaling", "Creb1 phosphorylation through the activation of adenylate cyclase", "Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde", "Cristae formation", "Crmps in sema3a signaling", "Cross presentation of soluble exogenous antigens endosomes", "Cs ds degradation", "Ctla4 inhibitory signaling", "Cyclin a b1 b2 associated events during g2 m transition", "Cyclin a cdk2 associated events at s phase entry", "Cyclin d associated events in g1", "Cytochrome c mediated apoptotic response", "Cytochrome p450 arranged by substrate type", "Cytokine signaling in immune system", "Cytoprotection by hmox1", "Cytosolic iron sulfur cluster assembly", "Cytosolic sensors of pathogen associated dna", "Cytosolic sulfonation of small molecules", "Cytosolic trna aminoacylation", "Dag and ip3 signaling", "Dap12 interactions", "Dap12 signaling", "Darpp 32 events", "Dcc mediated attractive signaling", "Ddx58 ifih1 mediated induction of interferon alpha beta", "Deactivation of the beta catenin transactivating complex", "Deadenylation dependent mrna decay", "Deadenylation of mrna", "Death receptor signalling", "Dectin 1 mediated noncanonical nf kb signaling", "Defective cftr causes cystic fibrosis", "Defective chst14 causes eds musculocontractural type", "Defective factor ix causes hemophilia b", "Defective intrinsic pathway for apoptosis", "Defects in biotin btn metabolism", "Defects in cobalamin b12 metabolism", "Defects in vitamin and cofactor metabolism", "Defects of contact activation system cas and kallikrein kinin system kks", "Degradation of axin", "Degradation of beta catenin by the destruction complex", "Degradation of cysteine and homocysteine", "Degradation of dvl", "Degradation of gli1 by the proteasome", "Degradation of the extracellular matrix", "Depolymerisation of the nuclear lamina", "Deposition of new cenpa containing nucleosomes at the centromere", "Dermatan sulfate biosynthesis", "Detoxification of reactive oxygen species", "Deubiquitination", "Developmental biology", "Dex h box helicases activate type i ifn and inflammatory cytokines production", "Digestion", "Digestion and absorption", "Disassembly of the destruction complex and recruitment of axin to the membrane", "Diseases associated with glycosaminoglycan metabolism", "Diseases associated with glycosylation precursor biosynthesis", "Diseases associated with n glycosylation of proteins", "Diseases associated with o glycosylation of proteins", "Diseases of carbohydrate metabolism", "Diseases of dna repair", "Diseases of glycosylation", "Diseases of immune system", "Diseases of metabolism", "Diseases of mismatch repair mmr", "Diseases of mitotic cell cycle", "Diseases of programmed cell death", "Diseases of signal transduction by growth factor receptors and second messengers", "Disinhibition of snare formation", "Disorders of transmembrane transporters", "Displacement of dna glycosylase by apex1", "Dissolution of fibrin clot", "Dna damage bypass", "Dna damage recognition in gg ner", "Dna damage reversal", "Dna damage telomere stress induced senescence", "Dna double strand break repair", "Dna double strand break response", "Dna methylation", "Dna repair", "Dna replication", "Dna replication initiation", "Dna replication pre initiation", "Dna strand elongation", "Dopamine clearance from the synaptic cleft", "Dopamine neurotransmitter release cycle", "Downregulation of erbb2 erbb3 signaling", "Downregulation of erbb2 signaling", "Downregulation of erbb4 signaling", "Downregulation of smad2 3 smad4 transcriptional activity", "Downregulation of tgf beta receptor signaling", "Downstream signal transduction", "Downstream signaling events of b cell receptor bcr", "Downstream signaling of activated fgfr1", "Downstream signaling of activated fgfr2", "Downstream signaling of activated fgfr3", "Downstream signaling of activated fgfr4", "Dscam interactions", "Dual incision in gg ner", "Dual incision in tc ner", "E2f enabled inhibition of pre replication complex formation", "E2f mediated regulation of dna replication", "E3 ubiquitin ligases ubiquitinate target proteins", "Early phase of hiv life cycle", "Ecm proteoglycans", "Effects of pip2 hydrolysis", "Egfr downregulation", "Egfr interacts with phospholipase c gamma", "Egfr transactivation by gastrin", "Egr2 and sox10 mediated initiation of schwann cell myelination", "Elastic fibre formation", "Endogenous sterols", "Endosomal sorting complex required for transport escrt", "Endosomal vacuolar pathway", "Energy dependent regulation of mtor by lkb1 ampk", "Enos activation", "Eph ephrin mediated repulsion of cells", "Eph ephrin signaling", "Epha mediated growth cone collapse", "Ephb mediated forward signaling", "Ephrin signaling", "Epigenetic regulation of gene expression", "Er quality control compartment erqc", "Er to golgi anterograde transport", "Erbb2 regulates cell motility", "Ercc6 csb and ehmt2 g9a positively regulate rrna expression", "Erk mapk targets", "Erks are inactivated", "Erythropoietin activates phospholipase c gamma plcg", "Erythropoietin activates ras", "Esr mediated signaling", "Establishment of sister chromatid cohesion", "Estrogen biosynthesis", "Estrogen dependent gene expression", "Estrogen dependent nuclear events downstream of esr membrane signaling", "Estrogen stimulated signaling through prkcz", "Ethanol oxidation", "Eukaryotic translation elongation", "Eukaryotic translation initiation", "Export of viral ribonucleoproteins from nucleus", "Extension of telomeres", "Extra nuclear estrogen signaling", "Extracellular matrix organization", "Factors involved in megakaryocyte development and platelet production", "Fanconi anemia pathway", "Fasl cd95l signaling", "Fatty acid metabolism", "Fatty acyl coa biosynthesis", "Fbxw7 mutants and notch1 in cancer", "Fc epsilon receptor fceri signaling", "Fceri mediated ca 2 mobilization", "Fceri mediated mapk activation", "Fceri mediated nf kb activation", "Fcgamma receptor fcgr dependent phagocytosis", "Fcgr3a mediated il10 synthesis", "Fgfr1 mutant receptor activation", "Fgfr2 alternative splicing", "Fgfr2 mutant receptor activation", "Fibronectin matrix formation", "Flt3 signaling", "Flt3 signaling in disease", "Folding of actin by cct tric", "Formation of apoptosome", "Formation of atp by chemiosmotic coupling", "Formation of fibrin clot clotting cascade", "Formation of incision complex in gg ner", "Formation of rna pol ii elongation complex", "Formation of senescence associated heterochromatin foci sahf", "Formation of tc ner pre incision complex", "Formation of the beta catenin tcf transactivating complex", "Formation of the cornified envelope", "Formation of the early elongation complex", "Formation of tubulin folding intermediates by cct tric", "Formation of xylulose 5 phosphate", "Formyl peptide receptors bind formyl peptides and many other ligands", "Foxo mediated transcription", "Foxo mediated transcription of oxidative stress metabolic and neuronal genes", "Free fatty acids regulate insulin secretion", "Frs mediated fgfr1 signaling", "Frs mediated fgfr2 signaling", "Frs mediated fgfr3 signaling", "Frs mediated fgfr4 signaling", "Fructose metabolism", "G alpha 12 13 signalling events", "G alpha i signalling events", "G alpha q signalling events", "G alpha s signalling events", "G alpha z signalling events", "G beta gamma signalling through cdc42", "G beta gamma signalling through pi3kgamma", "G protein activation", "G protein beta gamma signalling", "G protein mediated events", "G0 and early g1", "G1 s dna damage checkpoints", "G1 s specific transcription", "G2 m checkpoints", "G2 m dna damage checkpoint", "G2 m dna replication checkpoint", "G2 phase", "Gab1 signalosome", "Gaba b receptor activation", "Gaba receptor activation", "Gaba synthesis release reuptake and degradation", "Galactose catabolism", "Gamma carboxylation hypusine formation and arylsulfatase activation", "Gamma carboxylation transport and amino terminal cleavage of proteins", "Gap filling dna repair synthesis and ligation in gg ner", "Gap junction assembly", "Gap junction degradation", "Gap junction trafficking and regulation", "Gastrin creb signalling pathway via pkc and mapk", "Gdp fucose biosynthesis", "Gene and protein expression by jak stat signaling after interleukin 12 stimulation", "Gene silencing by rna", "Generation of second messenger molecules", "Global genome nucleotide excision repair gg ner", "Glucagon like peptide 1 glp1 regulates insulin secretion", "Glucagon signaling in metabolic regulation", "Glucagon type ligand receptors", "Gluconeogenesis", "Glucose metabolism", "Glucuronidation", "Glutamate and glutamine metabolism", "Glutamate neurotransmitter release cycle", "Glutathione conjugation", "Glutathione synthesis and recycling", "Glycerophospholipid biosynthesis", "Glycerophospholipid catabolism", "Glycogen breakdown glycogenolysis", "Glycogen metabolism", "Glycogen storage diseases", "Glycogen synthesis", "Glycolysis", "Glycosaminoglycan metabolism", "Glycosphingolipid metabolism", "Glyoxylate metabolism and glycine degradation", "Golgi associated vesicle biogenesis", "Golgi cisternae pericentriolar stack reorganization", "Golgi to er retrograde transport", "Gp1b ix v activation signalling", "Gpcr ligand binding", "Gpvi mediated activation cascade", "Grb2 events in erbb2 signaling", "Grb2 sos provides linkage to mapk signaling for integrins", "Growth hormone receptor signaling", "Hats acetylate histones", "Hcmv early events", "Hcmv infection", "Hcmv late events", "Hdacs deacetylate histones", "Hdl assembly", "Hdl clearance", "Hdms demethylate histones", "Hdr through homologous recombination hrr", "Hdr through mmej alt nhej", "Hdr through single strand annealing ssa", "Hedgehog ligand biogenesis", "Hedgehog off state", "Hedgehog on state", "Heme biosynthesis", "Heme degradation", "Heme signaling", "Hemostasis", "Heparan sulfate heparin hs gag metabolism", "Hiv elongation arrest and recovery", "Hiv infection", "Hiv life cycle", "Hiv transcription elongation", "Hiv transcription initiation", "Homologous dna pairing and strand exchange", "Homology directed repair", "Host interactions of hiv factors", "Hs gag degradation", "Hsf1 activation", "Hsf1 dependent transactivation", "Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand", "Hur elavl1 binds and stabilizes mrna", "Hyaluronan metabolism", "Hyaluronan uptake and degradation", "Hydrolysis of lpc", "Ikba variant leads to eda id", "Ikk complex recruitment mediated by rip1", "Immunoregulatory interactions between a lymphoid and a non lymphoid cell", "Inactivation of cdc42 and rac1", "Inactivation of csf3 g csf signaling", "Incretin synthesis secretion and inactivation", "Infection with mycobacterium tuberculosis", "Infectious disease", "Inflammasomes", "Influenza infection", "Inhibition of dna recombination at telomere", "Inhibition of replication initiation of damaged dna by rb1 e2f1", "Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components", "Initiation of nuclear envelope ne reformation", "Inla mediated entry of listeria monocytogenes into host cells", "Inlb mediated entry of listeria monocytogenes into host cell", "Innate immune system", "Inositol phosphate metabolism", "Insertion of tail anchored proteins into the endoplasmic reticulum membrane", "Insulin processing", "Insulin receptor recycling", "Insulin receptor signalling cascade", "Integration of energy metabolism", "Integration of provirus", "Integrin cell surface interactions", "Integrin signaling", "Interaction between l1 and ankyrins", "Interactions of rev with host cellular proteins", "Interactions of vpr with host cellular proteins", "Interconversion of nucleotide di and triphosphates", "Interferon alpha beta signaling", "Interferon gamma signaling", "Interferon signaling", "Interleukin 1 family signaling", "Interleukin 1 signaling", "Interleukin 10 signaling", "Interleukin 12 family signaling", "Interleukin 12 signaling", "Interleukin 15 signaling", "Interleukin 17 signaling", "Interleukin 2 family signaling", "Interleukin 20 family signaling", "Interleukin 21 signaling", "Interleukin 23 signaling", "Interleukin 27 signaling", "Interleukin 3 interleukin 5 and gm csf signaling", "Interleukin 35 signalling", "Interleukin 37 signaling", "Interleukin 4 and interleukin 13 signaling", "Interleukin 6 family signaling", "Interleukin 6 signaling", "Interleukin 7 signaling", "Interleukin 9 signaling", "Interleukin receptor shc signaling", "Intra golgi and retrograde golgi to er traffic", "Intra golgi traffic", "Intracellular signaling by second messengers", "Intraflagellar transport", "Intrinsic pathway for apoptosis", "Intrinsic pathway of fibrin clot formation", "Inwardly rectifying k channels", "Ion channel transport", "Ion homeostasis", "Ion transport by p type atpases", "Ionotropic activity of kainate receptors", "Irak1 recruits ikk complex", "Irak2 mediated activation of tak1 complex", "Irak4 deficiency tlr2 4", "Ire1alpha activates chaperones", "Irf3 mediated activation of type 1 ifn", "Irf3 mediated induction of type i ifn", "Iron uptake and transport", "Irs mediated signalling", "Jnk c jun kinases phosphorylation and activation mediated by activated human tak1", "Josephin domain dubs", "Keratan sulfate biosynthesis", "Keratan sulfate degradation", "Keratan sulfate keratin metabolism", "Keratinization", "Ketone body metabolism", "Killing mechanisms", "Kinesins", "Ksrp khsrp binds and destabilizes mrna", "L1cam interactions", "Lagging strand synthesis", "Laminin interactions", "Late endosomal microautophagy", "Ldl clearance", "Ldl remodeling", "Leishmania infection", "Lgi adam interactions", "Linoleic acid la metabolism", "Lipophagy", "Listeria monocytogenes entry into host cells", "Long term potentiation", "Loss of function of mecp2 in rett syndrome", "Loss of mecp2 binding ability to the ncor smrt complex", "Lrr flii interacting protein 1 lrrfip1 activates type i ifn production", "Lysine catabolism", "Lysosome vesicle biogenesis", "M phase", "Map2k and mapk activation", "Map3k8 tpl2 dependent mapk1 3 activation", "Mapk family signaling cascades", "Mapk targets nuclear events mediated by map kinases", "Mapk1 erk2 activation", "Mapk3 erk1 activation", "Mapk6 mapk4 signaling", "Mastl facilitates mitotic progression", "Maturation of protein 3a", "Maturation of sars cov 1 spike protein", "Maturation of sars cov 2 nucleoprotein", "Maturation of sars cov 2 spike protein", "Mecp2 regulates neuronal receptors and channels", "Mecp2 regulates transcription factors", "Mecp2 regulates transcription of neuronal ligands", "Meiosis", "Meiotic recombination", "Meiotic synapsis", "Membrane trafficking", "Met activates pi3k akt signaling", "Met activates ptk2 signaling", "Met activates ptpn11", "Met activates rap1 and rac1", "Met activates ras signaling", "Met interacts with tns proteins", "Met promotes cell motility", "Met receptor activation", "Met receptor recycling", "Metabolic disorders of biological oxidation enzymes", "Metabolism of amino acids and derivatives", "Metabolism of carbohydrates", "Metabolism of cofactors", "Metabolism of fat soluble vitamins", "Metabolism of folate and pterines", "Metabolism of ingested semet sec mesec into h2se", "Metabolism of lipids", "Metabolism of nitric oxide nos3 activation and regulation", "Metabolism of nucleotides", "Metabolism of polyamines", "Metabolism of porphyrins", "Metabolism of rna", "Metabolism of steroid hormones", "Metabolism of steroids", "Metabolism of vitamins and cofactors", "Metabolism of water soluble vitamins and cofactors", "Metal ion slc transporters", "Metalloprotease dubs", "Methionine salvage pathway", "Methylation", "Mhc class ii antigen presentation", "Microrna mirna biogenesis", "Miro gtpase cycle", "Miscellaneous transport and binding events", "Mismatch repair", "Mitochondrial biogenesis", "Mitochondrial calcium ion transport", "Mitochondrial fatty acid beta oxidation", "Mitochondrial fatty acid beta oxidation of saturated fatty acids", "Mitochondrial fatty acid beta oxidation of unsaturated fatty acids", "Mitochondrial iron sulfur cluster biogenesis", "Mitochondrial protein import", "Mitochondrial translation", "Mitochondrial trna aminoacylation", "Mitophagy", "Mitotic g1 phase and g1 s transition", "Mitotic g2 g2 m phases", "Mitotic metaphase and anaphase", "Mitotic prometaphase", "Mitotic prophase", "Mitotic spindle checkpoint", "Mitotic telophase cytokinesis", "Molecules associated with elastic fibres", "Molybdenum cofactor biosynthesis", "Mrna capping", "Mrna decay by 3 to 5 exoribonuclease", "Mrna decay by 5 to 3 exoribonuclease", "Mrna editing", "Mrna splicing", "Mrna splicing minor pathway", "Mtor signalling", "Mtorc1 mediated signalling", "Mucopolysaccharidoses", "Muscle contraction", "Myd88 independent tlr4 cascade", "Myoclonic epilepsy of lafora", "Myogenesis", "N glycan trimming in the er and calnexin calreticulin cycle", "Nade modulates death signalling", "Ncam signaling for neurite out growth", "Neddylation", "Nef and signal transduction", "Nef mediated cd4 down regulation", "Nef mediated cd8 down regulation", "Nef mediated downregulation of mhc class i complex cell surface expression", "Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters", "Negative epigenetic regulation of rrna expression", "Negative feedback regulation of mapk pathway", "Negative regulation of fgfr1 signaling", "Negative regulation of fgfr2 signaling", "Negative regulation of fgfr3 signaling", "Negative regulation of fgfr4 signaling", "Negative regulation of flt3", "Negative regulation of mapk pathway", "Negative regulation of met activity", "Negative regulation of nmda receptor mediated neuronal transmission", "Negative regulation of notch4 signaling", "Negative regulation of the pi3k akt network", "Negative regulators of ddx58 ifih1 signaling", "Nephrin family interactions", "Nervous system development", "Netrin 1 signaling", "Netrin mediated repulsion signals", "Neurexins and neuroligins", "Neurofascin interactions", "Neuronal system", "Neurotoxicity of clostridium toxins", "Neurotransmitter clearance", "Neurotransmitter receptors and postsynaptic signal transmission", "Neurotransmitter release cycle", "Neutrophil degranulation", "Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10", "Ngf stimulated transcription", "Nicotinamide salvaging", "Nicotinate metabolism", "Nod1 2 signaling pathway", "Non integrin membrane ecm interactions", "Noncanonical activation of notch3", "Nonhomologous end joining nhej", "Nonsense mediated decay nmd", "Nostrin mediated enos trafficking", "Notch hlh transcription pathway", "Notch1 intracellular domain regulates transcription", "Notch2 activation and transmission of signal to the nucleus", "Notch3 activation and transmission of signal to the nucleus", "Notch3 intracellular domain regulates transcription", "Notch4 activation and transmission of signal to the nucleus", "Notch4 intracellular domain regulates transcription", "Nr1h2 and nr1h3 mediated signaling", "Nr1h2 nr1h3 regulate gene expression linked to lipogenesis", "Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux", "Nrage signals death through jnk", "Nrcam interactions", "Nrif signals cell death from the nucleus", "Ns1 mediated effects on host pathways", "Ntrk2 activates rac1", "Nuclear envelope breakdown", "Nuclear envelope ne reassembly", "Nuclear events kinase and transcription factor activation", "Nuclear events stimulated by alk signaling in cancer", "Nuclear import of rev protein", "Nuclear pore complex npc disassembly", "Nuclear receptor transcription pathway", "Nuclear signaling by erbb4", "Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways", "Nucleotide biosynthesis", "Nucleotide catabolism", "Nucleotide excision repair", "Nucleotide salvage", "O linked glycosylation", "O linked glycosylation of mucins", "Oas antiviral response", "Oncogene induced senescence", "Oncogenic mapk signaling", "Opioid signalling", "Orc1 removal from chromatin", "Organelle biogenesis and maintenance", "Organic anion transporters", "Other interleukin signaling", "Other semaphorin interactions", "Ovarian tumor domain proteases", "Oxidative stress induced senescence", "P130cas linkage to mapk signaling for integrins", "P38mapk events", "P75 ntr receptor mediated signalling", "P75ntr negatively regulates cell cycle via sc1", "P75ntr regulates axonogenesis", "Parasite infection", "Passive transport by aquaporins", "Pcna dependent long patch base excision repair", "Pcp ce pathway", "Pd 1 signaling", "Pecam1 interactions", "Pentose phosphate pathway", "Peptide hormone metabolism", "Peptide ligand binding receptors", "Perk regulates gene expression", "Peroxisomal lipid metabolism", "Peroxisomal protein import", "Pexophagy", "Phase i functionalization of compounds", "Phase ii conjugation of compounds", "Phenylalanine and tyrosine metabolism", "Phenylalanine metabolism", "Phosphate bond hydrolysis by nudt proteins", "Phospholipase c mediated cascade fgfr2", "Phospholipase c mediated cascade fgfr4", "Phospholipid metabolism", "Phosphorylation of emi1", "Phosphorylation of the apc c", "Pi 3k cascade fgfr1", "Pi 3k cascade fgfr2", "Pi 3k cascade fgfr3", "Pi 3k cascade fgfr4", "Pi metabolism", "Pi3k akt activation", "Pi3k akt signaling in cancer", "Pi3k events in erbb2 signaling", "Pi5p regulates tp53 acetylation", "Pink1 prkn mediated mitophagy", "Piwi interacting rna pirna biogenesis", "Pka activation in glucagon signalling", "Pka mediated phosphorylation of creb", "Pka mediated phosphorylation of key metabolic factors", "Pkmts methylate histone lysines", "Plasma lipoprotein assembly", "Plasma lipoprotein assembly remodeling and clearance", "Plasma lipoprotein clearance", "Plasma lipoprotein remodeling", "Platelet activation signaling and aggregation", "Platelet adhesion to exposed collagen", "Platelet aggregation plug formation", "Platelet calcium homeostasis", "Platelet homeostasis", "Platelet sensitization by ldl", "Polb dependent long patch base excision repair", "Polo like kinase mediated events", "Polymerase switching", "Polymerase switching on the c strand of the telomere", "Positive epigenetic regulation of rrna expression", "Post chaperonin tubulin folding pathway", "Post translational modification synthesis of gpi anchored proteins", "Post translational protein modification", "Postmitotic nuclear pore complex npc reformation", "Potassium channels", "Potential therapeutics for sars", "Pou5f1 oct4 sox2 nanog activate genes related to proliferation", "Pp2a mediated dephosphorylation of key metabolic factors", "Prc2 methylates histones and dna", "Pre notch expression and processing", "Pre notch processing in golgi", "Pre notch processing in the endoplasmic reticulum", "Pregnenolone biosynthesis", "Presynaptic function of kainate receptors", "Prevention of phagosomal lysosomal fusion", "Processing and activation of sumo", "Processing of capped intron containing pre mrna", "Processing of capped intronless pre mrna", "Processing of dna double strand break ends", "Processing of intronless pre mrnas", "Processing of smdt1", "Processive synthesis on the c strand of the telomere", "Processive synthesis on the lagging strand", "Programmed cell death", "Prolactin receptor signaling", "Prolonged erk activation events", "Propionyl coa catabolism", "Prostacyclin signalling through prostacyclin receptor", "Protein folding", "Protein localization", "Protein methylation", "Protein protein interactions at synapses", "Protein repair", "Protein ubiquitination", "Proton coupled monocarboxylate transport", "Pten regulation", "Ptk6 expression", "Ptk6 regulates cell cycle", "Ptk6 regulates proteins involved in rna processing", "Ptk6 regulates rho gtpases ras gtpase and map kinases", "Ptk6 regulates rtks and their effectors akt1 and dok1", "Purine catabolism", "Purine ribonucleoside monophosphate biosynthesis", "Purine salvage", "Purinergic signaling in leishmaniasis infection", "Pyrimidine catabolism", "Pyrimidine salvage", "Pyroptosis", "Pyruvate metabolism", "Pyruvate metabolism and citric acid tca cycle", "Ra biosynthesis pathway", "Rab gefs exchange gtp for gdp on rabs", "Rab geranylgeranylation", "Rab regulation of trafficking", "Rac1 gtpase cycle", "Rac2 gtpase cycle", "Rac3 gtpase cycle", "Raf activation", "Raf independent mapk1 3 activation", "Rap1 signalling", "Ras activation upon ca2 influx through nmda receptor", "Ras processing", "Receptor mediated mitophagy", "Recognition and association of dna glycosylase with site containing an affected purine", "Recognition of dna damage by pcna containing replication complex", "Recruitment of mitotic centrosome proteins and complexes", "Recruitment of numa to mitotic centrosomes", "Recycling of eif2 gdp", "Recycling pathway of l1", "Reduction of cytosolic ca levels", "Regulated necrosis", "Regulated proteolysis of p75ntr", "Regulation by c flip", "Regulation of bach1 activity", "Regulation of beta cell development", "Regulation of cholesterol biosynthesis by srebp srebf", "Regulation of cytoskeletal remodeling and cell spreading by ipp complex components", "Regulation of expression of slits and robos", "Regulation of foxo transcriptional activity by acetylation", "Regulation of gene expression in beta cells", "Regulation of gene expression in late stage branching morphogenesis pancreatic bud precursor cells", "Regulation of glucokinase by glucokinase regulatory protein", "Regulation of glycolysis by fructose 2 6 bisphosphate metabolism", "Regulation of hmox1 expression and activity", "Regulation of hsf1 mediated heat shock response", "Regulation of ifna signaling", "Regulation of ifng signaling", "Regulation of innate immune responses to cytosolic dna", "Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps", "Regulation of insulin secretion", "Regulation of kit signaling", "Regulation of lipid metabolism by pparalpha", "Regulation of localization of foxo transcription factors", "Regulation of mecp2 expression and activity", "Regulation of mrna stability by proteins that bind au rich elements", "Regulation of plk1 activity at g2 m transition", "Regulation of pten gene transcription", "Regulation of pten localization", "Regulation of pten mrna translation", "Regulation of pten stability and activity", "Regulation of pyruvate dehydrogenase pdh complex", "Regulation of ras by gaps", "Regulation of runx1 expression and activity", "Regulation of runx2 expression and activity", "Regulation of runx3 expression and activity", "Regulation of signaling by cbl", "Regulation of tlr by endogenous ligand", "Regulation of tnfr1 signaling", "Regulation of tp53 activity", "Regulation of tp53 activity through acetylation", "Regulation of tp53 activity through association with co factors", "Regulation of tp53 activity through methylation", "Regulation of tp53 activity through phosphorylation", "Regulation of tp53 expression and degradation", "Release of apoptotic factors from the mitochondria", "Repression of wnt target genes", "Reproduction", "Resolution of abasic sites ap sites", "Resolution of ap sites via the multiple nucleotide patch replacement pathway", "Resolution of d loop structures", "Resolution of d loop structures through synthesis dependent strand annealing sdsa", "Resolution of sister chromatid cohesion", "Respiratory electron transport", "Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins", "Response of eif2ak1 hri to heme deficiency", "Response of eif2ak4 gcn2 to amino acid deficiency", "Response of mtb to phagocytosis", "Response to elevated platelet cytosolic ca2", "Ret signaling", "Retinoid cycle disease events", "Retrograde neurotrophin signalling", "Retrograde transport at the trans golgi network", "Rho gtpase cycle", "Rho gtpase effectors", "Rho gtpases activate cit", "Rho gtpases activate formins", "Rho gtpases activate iqgaps", "Rho gtpases activate ktn1", "Rho gtpases activate nadph oxidases", "Rho gtpases activate paks", "Rho gtpases activate pkns", "Rho gtpases activate rhotekin and rhophilins", "Rho gtpases activate rocks", "Rho gtpases activate wasps and waves", "Rhoa gtpase cycle", "Rhob gtpase cycle", "Rhobtb gtpase cycle", "Rhobtb1 gtpase cycle", "Rhobtb2 gtpase cycle", "Rhobtb3 atpase cycle", "Rhoc gtpase cycle", "Rhod gtpase cycle", "Rhof gtpase cycle", "Rhog gtpase cycle", "Rhoh gtpase cycle", "Rhoj gtpase cycle", "Rhoq gtpase cycle", "Rhot1 gtpase cycle", "Rhou gtpase cycle", "Rhov gtpase cycle", "Rip mediated nfkb activation via zbp1", "Ripk1 mediated regulated necrosis", "Rmts methylate histone arginines", "Rna polymerase i promoter escape", "Rna polymerase i transcription", "Rna polymerase i transcription initiation", "Rna polymerase i transcription termination", "Rna polymerase ii transcribes snrna genes", "Rna polymerase ii transcription", "Rna polymerase ii transcription termination", "Rna polymerase iii chain elongation", "Rna polymerase iii transcription", "Rna polymerase iii transcription initiation from type 1 promoter", "Rna polymerase iii transcription initiation from type 3 promoter", "Rna polymerase iii transcription termination", "Rnd1 gtpase cycle", "Rnd2 gtpase cycle", "Rnd3 gtpase cycle", "Robo receptors bind akap5", "Role of abl in robo slit signaling", "Role of lat2 ntal lab on calcium mobilization", "Role of phospholipids in phagocytosis", "Role of second messengers in netrin 1 signaling", "Rora activates gene expression", "Ros and rns production in phagocytes", "Rrna modification in the nucleus and cytosol", "Rrna processing", "Rrna processing in the mitochondrion", "Rsk activation", "Runx1 and foxp3 control the development of regulatory t lymphocytes tregs", "Runx1 interacts with co factors whose precise effect on runx1 targets is not known", "Runx1 regulates estrogen receptor mediated transcription", "Runx1 regulates expression of components of tight junctions", "Runx1 regulates genes involved in megakaryocyte differentiation and platelet function", "Runx1 regulates transcription of genes involved in bcr signaling", "Runx1 regulates transcription of genes involved in differentiation of hscs", "Runx1 regulates transcription of genes involved in differentiation of keratinocytes", "Runx1 regulates transcription of genes involved in differentiation of myeloid cells", "Runx1 regulates transcription of genes involved in interleukin signaling", "Runx1 regulates transcription of genes involved in wnt signaling", "Runx2 regulates bone development", "Runx2 regulates chondrocyte maturation", "Runx2 regulates genes involved in cell migration", "Runx2 regulates osteoblast differentiation", "Runx3 regulates cdkn1a transcription", "Runx3 regulates immune response and cell migration", "Runx3 regulates notch signaling", "Runx3 regulates p14 arf", "Runx3 regulates wnt signaling", "S phase", "Sars cov 1 infection", "Sars cov 2 infection", "Sars cov infections", "Scavenging by class a receptors", "Scavenging by class b receptors", "Scavenging by class f receptors", "Scf skp2 mediated degradation of p27 p21", "Sealing of the nuclear envelope ne by escrt iii", "Selective autophagy", "Selenoamino acid metabolism", "Sema3a pak dependent axon repulsion", "Sema3a plexin repulsion signaling by inhibiting integrin adhesion", "Sema4d in semaphorin signaling", "Sema4d induced cell migration and growth cone collapse", "Sema4d mediated inhibition of cell attachment and migration", "Semaphorin interactions", "Senescence associated secretory phenotype sasp", "Sensing of dna double strand breaks", "Sensory perception", "Sensory processing of sound", "Sensory processing of sound by outer hair cells of the cochlea", "Separation of sister chromatids", "Serine biosynthesis", "Shc mediated cascade fgfr1", "Shc mediated cascade fgfr3", "Shc mediated cascade fgfr4", "Shc related events triggered by igf1r", "Shc1 events in egfr signaling", "Shc1 events in erbb2 signaling", "Shc1 events in erbb4 signaling", "Sialic acid metabolism", "Signal amplification", "Signal attenuation", "Signal regulatory protein family interactions", "Signal transduction by l1", "Signaling by activin", "Signaling by alk", "Signaling by alk in cancer", "Signaling by bmp", "Signaling by braf and raf1 fusions", "Signaling by csf3 g csf", "Signaling by ctnnb1 phospho site mutants", "Signaling by cytosolic fgfr1 fusion mutants", "Signaling by egfr", "Signaling by egfr in cancer", "Signaling by erbb2", "Signaling by erbb2 ecd mutants", "Signaling by erbb2 in cancer", "Signaling by erbb4", "Signaling by erythropoietin", "Signaling by fgfr", "Signaling by fgfr in disease", "Signaling by fgfr1", "Signaling by fgfr1 in disease", "Signaling by fgfr2", "Signaling by fgfr2 iiia tm", "Signaling by fgfr2 in disease", "Signaling by fgfr3", "Signaling by fgfr3 fusions in cancer", "Signaling by fgfr4", "Signaling by fgfr4 in disease", "Signaling by flt3 fusion proteins", "Signaling by flt3 itd and tkd mutants", "Signaling by gpcr", "Signaling by hedgehog", "Signaling by hippo", "Signaling by insulin receptor", "Signaling by interleukins", "Signaling by kit in disease", "Signaling by leptin", "Signaling by mapk mutants", "Signaling by met", "Signaling by moderate kinase activity braf mutants", "Signaling by mras complex mutants", "Signaling by mst1", "Signaling by nodal", "Signaling by notch", "Signaling by notch1", "Signaling by notch1 pest domain mutants in cancer", "Signaling by notch2", "Signaling by notch3", "Signaling by notch4", "Signaling by ntrk2 trkb", "Signaling by ntrk3 trkc", "Signaling by ntrks", "Signaling by nuclear receptors", "Signaling by pdgf", "Signaling by pdgfr in disease", "Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants", "Signaling by ptk6", "Signaling by receptor tyrosine kinases", "Signaling by retinoic acid", "Signaling by rho gtpases miro gtpases and rhobtb3", "Signaling by robo receptors", "Signaling by scf kit", "Signaling by tgf beta receptor complex", "Signaling by tgf beta receptor complex in cancer", "Signaling by tgfb family members", "Signaling by the b cell receptor bcr", "Signaling by type 1 insulin like growth factor 1 receptor igf1r", "Signaling by vegf", "Signaling by wnt", "Signaling by wnt in cancer", "Signalling to erks", "Signalling to ras", "Sirt1 negatively regulates rrna expression", "Slbp dependent processing of replication dependent histone pre mrnas", "Slc mediated transmembrane transport", "Slc transporter disorders", "Smac xiap regulated apoptotic response", "Smad2 smad3 smad4 heterotrimer regulates transcription", "Small interfering rna sirna biogenesis", "Smooth muscle contraction", "Snrnp assembly", "Sodium calcium exchangers", "Sos mediated signalling", "Sphingolipid de novo biosynthesis", "Sphingolipid metabolism", "Spry regulation of fgf signaling", "Srp dependent cotranslational protein targeting to membrane", "Stabilization of p53", "Stat3 nuclear events downstream of alk signaling", "Stat5 activation", "Stat5 activation downstream of flt3 itd mutants", "Stimuli sensing channels", "Sting mediated induction of host immune responses", "Striated muscle contraction", "Sulfide oxidation to sulfate", "Sulfur amino acid metabolism", "Sumo is conjugated to e1 uba2 sae1", "Sumo is transferred from e1 to e2 ube2i ubc9", "Sumoylation", "Sumoylation of chromatin organization proteins", "Sumoylation of dna damage response and repair proteins", "Sumoylation of dna methylation proteins", "Sumoylation of dna replication proteins", "Sumoylation of rna binding proteins", "Sumoylation of sumoylation proteins", "Sumoylation of transcription cofactors", "Sumoylation of transcription factors", "Sumoylation of ubiquitinylation proteins", "Suppression of apoptosis", "Suppression of phagosomal maturation", "Surfactant metabolism", "Switching of origins to a post replicative state", "Synaptic adhesion like molecules", "Syndecan interactions", "Synthesis of 5 eicosatetraenoic acids", "Synthesis of active ubiquitin roles of e1 and e2 enzymes", "Synthesis of bile acids and bile salts", "Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol", "Synthesis of diphthamide eef2", "Synthesis of dna", "Synthesis of dolichyl phosphate", "Synthesis of epoxy eet and dihydroxyeicosatrienoic acids dhet", "Synthesis of gdp mannose", "Synthesis of ip2 ip and ins in the cytosol", "Synthesis of ip3 and ip4 in the cytosol", "Synthesis of ketone bodies", "Synthesis of leukotrienes lt and eoxins ex", "Synthesis of lipoxins lx", "Synthesis of pa", "Synthesis of pc", "Synthesis of pe", "Synthesis of pg", "Synthesis of pi", "Synthesis of pips at the early endosome membrane", "Synthesis of pips at the er membrane", "Synthesis of pips at the golgi membrane", "Synthesis of pips at the late endosome membrane", "Synthesis of pips at the plasma membrane", "Synthesis of prostaglandins pg and thromboxanes tx", "Synthesis of pyrophosphates in the cytosol", "Synthesis of substrates in n glycan biosythesis", "Synthesis of udp n acetyl glucosamine", "Synthesis of very long chain fatty acyl coas", "Synthesis secretion and deacylation of ghrelin", "Synthesis secretion and inactivation of glucagon like peptide 1 glp 1", "Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip", "Tak1 activates nfkb by phosphorylation and activation of ikks complex", "Tbc rabgaps", "Tcf dependent signaling in response to wnt", "Tcr signaling", "Telomere c strand lagging strand synthesis", "Telomere c strand synthesis initiation", "Telomere extension by telomerase", "Telomere maintenance", "Termination of translesion dna synthesis", "Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation", "Tfap2a acts as a transcriptional repressor during retinoic acid induced cell differentiation", "Tgf beta receptor signaling activates smads", "Tgf beta receptor signaling in emt epithelial to mesenchymal transition", "The activation of arylsulfatases", "The canonical retinoid cycle in rods twilight vision", "The citric acid tca cycle and respiratory electron transport", "The nlrp3 inflammasome", "The phototransduction cascade", "The role of gtse1 in g2 m progression after g2 checkpoint", "The role of nef in hiv 1 replication and disease pathogenesis", "Thrombin signalling through proteinase activated receptors pars", "Thromboxane signalling through tp receptor", "Ticam1 rip1 mediated ikk complex recruitment", "Ticam1 traf6 dependent induction of tak1 complex", "Tie2 signaling", "Tight junction interactions", "Tnf signaling", "Tnfr1 induced nfkappab signaling pathway", "Tnfr1 mediated ceramide production", "Tnfr2 non canonical nf kb pathway", "Toll like receptor 9 tlr9 cascade", "Toll like receptor cascades", "Toll like receptor tlr1 tlr2 cascade", "Toxicity of botulinum toxin type d botd", "Tp53 regulates metabolic genes", "Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain", "Tp53 regulates transcription of caspase activators and caspases", "Tp53 regulates transcription of cell cycle genes", "Tp53 regulates transcription of cell death genes", "Tp53 regulates transcription of death receptors and ligands", "Tp53 regulates transcription of dna repair genes", "Tp53 regulates transcription of genes involved in cytochrome c release", "Tp53 regulates transcription of genes involved in g1 cell cycle arrest", "Tp53 regulates transcription of genes involved in g2 cell cycle arrest", "Tp53 regulates transcription of several additional cell death genes whose specific roles in p53 dependent apoptosis remain uncertain", "Traf3 dependent irf activation pathway", "Traf6 mediated induction of tak1 complex within tlr4 complex", "Traf6 mediated irf7 activation", "Traf6 mediated irf7 activation in tlr7 8 or 9 signaling", "Traf6 mediated nf kb activation", "Trafficking and processing of endosomal tlr", "Trafficking of ampa receptors", "Trafficking of glur2 containing ampa receptors", "Trafficking of myristoylated proteins to the cilium", "Trans golgi network vesicle budding", "Transcription coupled nucleotide excision repair tc ner", "Transcription of e2f targets under negative control by dream complex", "Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1", "Transcription of the hiv genome", "Transcriptional activation of mitochondrial biogenesis", "Transcriptional activity of smad2 smad3 smad4 heterotrimer", "Transcriptional regulation by e2f6", "Transcriptional regulation by mecp2", "Transcriptional regulation by runx1", "Transcriptional regulation by runx2", "Transcriptional regulation by runx3", "Transcriptional regulation by small rnas", "Transcriptional regulation by the ap 2 tfap2 family of transcription factors", "Transcriptional regulation by tp53", "Transcriptional regulation by ventx", "Transcriptional regulation of granulopoiesis", "Transcriptional regulation of pluripotent stem cells", "Transcriptional regulation of white adipocyte differentiation", "Transferrin endocytosis and recycling", "Translation", "Translation of replicase and assembly of the replication transcription complex", "Translation of sars cov 1 structural proteins", "Translation of sars cov 2 structural proteins", "Translesion synthesis by polh", "Translesion synthesis by polk", "Translesion synthesis by y family dna polymerases bypasses lesions on dna template", "Translocation of slc2a4 glut4 to the plasma membrane", "Transmission across chemical synapses", "Transport and synthesis of paps", "Transport of bile salts and organic acids metal ions and amine compounds", "Transport of connexons to the plasma membrane", "Transport of fatty acids", "Transport of inorganic cations anions and amino acids oligopeptides", "Transport of mature mrnas derived from intronless transcripts", "Transport of mature transcript to cytoplasm", "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane", "Transport of nucleotide sugars", "Transport of small molecules", "Transport of the slbp dependant mature mrna", "Transport of vitamins nucleosides and related molecules", "Transport to the golgi and subsequent modification", "Triglyceride catabolism", "Triglyceride metabolism", "Tristetraprolin ttp zfp36 binds and destabilizes mrna", "Trna aminoacylation", "Trna modification in the mitochondrion", "Trna modification in the nucleus and cytosol", "Trna processing", "Trna processing in the mitochondrion", "Trna processing in the nucleus", "Tryptophan catabolism", "Type i hemidesmosome assembly", "Tyrosine catabolism", "Tysnd1 cleaves peroxisomal proteins", "Ub specific processing proteases", "Uch proteinases", "Unblocking of nmda receptors glutamate binding and activation", "Unfolded protein response upr", "Unwinding of dna", "Uptake and actions of bacterial toxins", "Uptake and function of anthrax toxins", "Uptake and function of diphtheria toxin", "Urea cycle", "Vasopressin regulates renal water homeostasis via aquaporins", "Vegfr2 mediated cell proliferation", "Vegfr2 mediated vascular permeability", "Vesicle mediated transport", "Viral messenger rna synthesis", "Visual phototransduction", "Vitamin b1 thiamin metabolism", "Vitamin b5 pantothenate metabolism", "Vitamin c ascorbate metabolism", "Vitamin d calciferol metabolism", "Vldl assembly", "Vldlr internalisation and degradation", "Vxpx cargo targeting to cilium", "Wax and plasmalogen biosynthesis", "Wnt ligand biogenesis and trafficking", "Wnt mediated activation of dvl", "Wnt5a dependent internalization of fzd2 fzd5 and ror2", "Wnt5a dependent internalization of fzd4", "Zbp1 dai mediated induction of type i ifns", "Zinc efflux and compartmentalization by the slc30 family", "Zinc transporters"], "available_proteins": ["AAAS", "AAMP", "AARS", "AARS2", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADH5", "ADI1", "ADK", "ADO", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPS", "AHCY", "AHCYL1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP12", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT1S1", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALKBH5", "ALYREF", "AMOT", "ANAPC16", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANKRD28", "ANLN", "ANP32A", "ANXA1", "ANXA2", "ANXA6", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP3B1", "AP3M1", "APEH", "APEX1", "APOOL", "APRT", "AQR", "ARCN1", "ARF4", "ARFGAP1", "ARFGAP2", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL6IP5", "ARMCX3", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "AS3MT", "ASAH1", "ASCC2", "ASCC3", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD3B", "ATG3", "ATG4B", "ATIC", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7B", "ATRX", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAK1", "BANF1", "BASP1", "BAX", "BAZ1B", "BCAP31", "BCAS2", "BCAT2", "BCL10", "BCS1L", "BET1", "BIRC6", "BLMH", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOP1", "BPNT1", "BRD2", "BSG", "BUB3", "BUD31", "BYSL", "C19orf70", "C1QBP", "C1orf35", "C2CD5", "C2orf49", "CAB39", "CAD", "CALD1", "CALR", "CALU", "CAND1", "CANX", "CAP1", "CAPN1", "CAPZA1", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CASP2", "CASP3", "CASP6", "CAST", "CBFB", "CBR1", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD47", "CD81", "CDC23", "CDC27", "CDC37", "CDC42", "CDC45", "CDC5L", "CDC73", "CDCA8", "CDK1", "CDK13", "CDK2", "CDK4", "CDK6", "CDKAL1", "CDKN2A", "CDS2", "CERS2", "CFL1", "CHAC2", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP2A", "CHMP5", "CHMP7", "CHORDC1", "CHST14", "CHUK", "CIAPIN1", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP2", "CLCN3", "CLCN7", "CLINT1", "CLNS1A", "CLP1", "CLSPN", "CLTA", "CLTC", "CMAS", "CMPK1", "CNDP2", "CNN2", "CNOT1", "CNOT11", "CNOT7", "CNOT9", "COASY", "COG7", "COL4A3BP", "COLGALT1", "COMMD10", "COMMD2", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COTL1", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT2", "CRK", "CRKL", "CRNKL1", "CRTAP", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC22", "CXADR", "CYB5B", "CYB5R3", "CYC1", "CYFIP1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAXX", "DBN1", "DBNL", "DCAF13", "DCAF7", "DCD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCXR", "DDA1", "DDB1", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX5", "DDX52", "DDX56", "DDX6", "DEK", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHFR", "DHPS", "DHRS7B", "DHX15", "DHX16", "DHX36", "DHX37", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB11", "DNAJB6", "DNAJC11", "DNAJC3", "DNAJC7", "DNAJC8", "DNM1", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOHH", "DPH2", "DPM1", "DPYSL2", "DPYSL3", "DSG2", "DSP", "DST", "DTL", "DTYMK", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "EARS2", "EBNA1BP2", "EBP", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFTUD2", "EHD1", "EHMT1", "EHMT2", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMD", "EMG1", "EML4", "ENDOD1", "ENO1", "ENOPH1", "ENSA", "ENY2", "EPB41", "EPB41L2", "EPB41L3", "EPHX1", "EPHX2", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERCC2", "ERCC6L", "ERI1", "ERLIN2", "ERO1A", "ERP44", "ESD", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EXO1", "EXOC2", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EYA3", "EZR", "F11R", "FABP5", "FADS2", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120B", "FAM3C", "FAM49B", "FAM91A1", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FAU", "FBL", "FBXO22", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FIP1L1", "FKBP14", "FKBP1A", "FKBP4", "FKBP5", "FKBP8", "FKBP9", "FLCN", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FN3KRP", "FNTA", "FNTB", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUCA2", "FUS", "FXR1", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALNT1", "GALNT2", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLM", "GCN1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GINS1", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLRX3", "GLRX5", "GLS", "GLTP", "GLUD1", "GM2A", "GMPPA", "GMPPB", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNE", "GNG12", "GNG5", "GNL3", "GNPDA1", "GNS", "GOLGA3", "GOLGB1", "GOLIM4", "GOPC", "GOT1", "GOT2", "GPAA1", "GPD2", "GPI", "GPKOW", "GPS1", "GPT2", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2E1", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C5", "GUSB", "GYG1", "GYS1", "H1F0", "H2AFX", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS4", "HAUS5", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HEBP1", "HECTD1", "HERC2", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMGA1", "HMGB1", "HMGB2", "HMGCL", "HMGCS1", "HMGN1", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HPRT1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HUWE1", "HYOU1", "IARS", "IARS2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "ILF2", "IMMT", "IMP3", "IMPAD1", "IMPDH2", "INCENP", "INTS3", "INTS9", "IPO5", "IPO8", "IPO9", "IQGAP1", "IRS4", "ISCU", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPK1", "IVD", "JUP", "KARS", "KAT7", "KDELR1", "KDM1A", "KDM1B", "KDM3B", "KDSR", "KHDRBS1", "KHSRP", "KIF11", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KLC1", "KLC2", "KLC4", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LAMP1", "LAMTOR1", "LAMTOR2", "LARS", "LARS2", "LAS1L", "LBR", "LCLAT1", "LDHA", "LDHB", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMNA", "LMNB1", "LNPEP", "LPCAT1", "LPGAT1", "LRPPRC", "LRRC1", "LSM2", "LSM6", "LSS", "LTA4H", "LTN1", "LTV1", "LYPLA1", "LZTFL1", "M6PR", "MAGED2", "MANF", "MAP2K1", "MAP2K2", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MARC1", "MARCKS", "MARS", "MAT2A", "MAT2B", "MAU2", "MAVS", "MCAT", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDC1", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED17", "MED24", "MED25", "METTL1", "MFN2", "MGST2", "MGST3", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MIPEP", "MLEC", "MMAB", "MMGT1", "MMS19", "MOGS", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP2", "MPRIP", "MPST", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL44", "MRPL45", "MRPL46", "MRPL50", "MRPL58", "MRPL9", "MRPS10", "MRPS15", "MRPS17", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR6", "MTOR", "MTX1", "MTX2", "MUT", "MVD", "MVK", "MYBBP1A", "MYDGF", "MYH10", "MYH9", "MYL6", "MYO1C", "MYO6", "NAA35", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAPA", "NAPG", "NARS", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCAPH2", "NCBP1", "NCK1", "NCKAP1", "NCL", "NCSTN", "NDC1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4", "NEFL", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NFS1", "NHLRC2", "NHP2", "NIP7", "NIPA2", "NIPSNAP2", "NLN", "NLRX1", "NME1", "NME2", "NMT1", "NNT", "NOC2L", "NOC4L", "NOL11", "NOL6", "NOL9", "NOP14", "NOP2", "NOP56", "NOP58", "NOSIP", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSMCE2", "NSUN2", "NSUN6", "NT5C2", "NT5C3A", "NT5C3B", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUDC", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "OAT", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC3", "OSBP", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTULIN", "OXA1L", "P3H1", "P4HA1", "P4HB", "PA2G4", "PABPC1", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAK2", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PDCD11", "PDCD4", "PDCD6", "PDCD6IP", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA5", "PDIA6", "PDK3", "PDLIM5", "PDS5A", "PDS5B", "PDXK", "PEBP1", "PECR", "PELP1", "PES1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF2", "PHF5A", "PHGDH", "PHIP", "PI4K2A", "PICALM", "PIGK", "PIGS", "PIGU", "PIK3C2A", "PIN1", "PIR", "PISD", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN2", "PLA2G15", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PMPCA", "PMPCB", "PMVK", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPO", "POFUT1", "POLA1", "POLA2", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAT", "PPIB", "PPID", "PPIH", "PPIL1", "PPIL3", "PPIL4", "PPM1F", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP5C", "PPT1", "PPT2", "PQBP1", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRIM1", "PRIM2", "PRKAA1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF6", "PRPF8", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PTBP1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPN1", "PTPN11", "PTRH2", "PUF60", "PUM1", "PUS1", "PUS7", "PWP2", "PXN", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB21", "RAB24", "RAB34", "RAB35", "RAB39A", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB8B", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD51AP1", "RAE1", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RAP1GDS1", "RAPGEF2", "RARS", "RASA1", "RBBP5", "RBBP6", "RBM14", "RBM17", "RBM28", "RBM4", "RBM8A", "RBMX", "RBP1", "RCC1", "RCC2", "RCL1", "RCN1", "RDH11", "RDH13", "RDH14", "RDX", "RETSAT", "REXO2", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RINT1", "RNASET2", "RNF114", "RNF14", "RNF40", "RNMT", "RNPS1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP8", "RRP9", "RSF1", "RSU1", "RTCB", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAMHD1", "SAMM50", "SAP18", "SAP30BP", "SARNP", "SARS", "SARS2", "SART1", "SC5D", "SCAMP1", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCO1", "SCO2", "SCP2", "SCRIB", "SDCBP", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEH1L", "SEL1L", "SENP3", "SEPT2", "SEPT7", "SERPINB6", "SERPINH1", "SET", "SETD7", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SGPL1", "SGTA", "SH3GL1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIN3A", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A26", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC30A5", "SLC35B2", "SLC3A2", "SLK", "SLTM", "SMARCA4", "SMARCA5", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMYD3", "SNAP23", "SNAP29", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX2", "SNX3", "SNX5", "SOAT1", "SOD2", "SORD", "SPAG9", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPEN", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAT3", "STIP1", "STK4", "STMN1", "STOML2", "STRAP", "STRN", "STT3A", "STUB1", "STX10", "STX17", "STX18", "STX4", "STX5", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGT1", "SULT2A1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SURF4", "SUZ12", "SV2A", "SYMPK", "SYNE2", "TAB1", "TACC3", "TACO1", "TAF15", "TAGLN2", "TALDO1", "TARS", "TARS2", "TBC1D15", "TBC1D4", "TBCA", "TBCB", "TBCD", "TBCE", "TBL3", "TCEA1", "TCP1", "TDP2", "TDRKH", "TECR", "TERF2IP", "TEX10", "TEX264", "TFAM", "TFG", "TFIP11", "TFRC", "TGOLN2", "THOC1", "THOC3", "THOP1", "THRAP3", "THUMPD1", "TIA1", "TIAL1", "TIMELESS", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TK1", "TKT", "TLN1", "TMED10", "TMED2", "TMED7", "TMEM11", "TMEM87A", "TMOD3", "TMPO", "TMPO", "TNPO1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TP53", "TP53BP1", "TPD52", "TPI1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPX2", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRIM21", "TRIM25", "TRIM27", "TRIM28", "TRIP12", "TRMT10C", "TRMT11", "TRMT112", "TRMT6", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSR1", "TSTA3", "TTC26", "TTC37", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXNDC5", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE2V1", "UBE3C", "UBE4A", "UBR4", "UBTF", "UBXN1", "UCHL5", "UCK2", "UFD1", "UFL1", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119B", "UNG", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USO1", "USP10", "USP11", "USP14", "USP19", "USP28", "USP33", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VPS26A", "VPS29", "VPS35", "VPS4A", "VPS51", "VPS53", "VRK1", "VRK3", "WAPL", "WARS", "WBP11", "WDR1", "WDR18", "WDR3", "WDR33", "WDR36", "WDR43", "WDR46", "WDR5", "WDR6", "WDR61", "WDR75", "WDR77", "WFS1", "WIPI2", "WRAP53", "WTAP", "XAB2", "XPO1", "XPO5", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YKT6", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZC3H11A", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZFYVE16", "ZNF512B", "ZNF638", "ZW10"], "leading_proteins": ["AARS2", "AATF", "ABCB10", "ABCB7", "ABCC1", "ABCC4", "ABCF1", "ABHD10", "ACOX1", "ACOX3", "ACTN2", "ADO", "AKAP12", "AKT1", "AKT1S1", "AKT2", "ALDH3A2", "ALDH5A1", "ALG1", "AMOT", "ANKFY1", "ANKLE2", "ANLN", "ANXA2", "AP1B1", "AP2A2", "ARFIP2", "ARHGAP17", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARL6IP5", "ARPC3", "ASNA1", "ATG4B", "ATP2A2", "ATP2B1", "ATP5B", "ATP5C1", "ATP5H", "ATP5I", "ATP6", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATRX", "BAG4", "BAG6", "BAIAP2", "BASP1", "BAX", "BCS1L", "BIRC6", "C19orf70", "CAB39", "CALR", "CAP1", "CAPN1", "CARS", "CASP2", "CASP3", "CASP6", "CBFB", "CCNB1", "CDC27", "CDC42", "CDCA8", "CDK13", "CDKN2A", "CDS2", "CHKA", "CHMP2A", "CHMP7", "CHUK", "CLP1", "CLTC", "CNOT1", "COASY", "COL4A3BP", "COPZ1", "COX4I1", "COX6C", "COX7C", "CPSF6", "CPT2", "CSNK2A2", "CTBP2", "CTNNB1", "CUL1", "CUL2", "CYB5B", "CYP51A1", "DAXX", "DCAF7", "DCTN4", "DDRGK1", "DDX39A", "DDX42", "DEK", "DERL1", "DGCR8", "DHCR24", "DHFR", "DHPS", "DIAPH1", "DIAPH3", "DLAT", "DLD", "DNAJB6", "DNAJC3", "DNM2", "DOHH", "DPH2", "DPYSL3", "DSP", "DYNC1LI2", "EARS2", "ECSIT", "EEF2", "EHD1", "EHMT2", "EIF3A", "EIF3F", "EIF3J", "EIF3M", "EIF4E", "EIF4G1", "EIF5B", "ELMO2", "ELOA", "ELOC", "EML4", "ENSA", "ERAL1", "ERCC2", "ERCC6L", "ETFB", "EXOC2", "EXOC4", "EXOC6", "EXOSC9", "FABP5", "FASN", "FAU", "FDXR", "FH", "FKBP5", "FKBP9", "FNTB", "GABARAPL2", "GADD45GIP1", "GATAD2A", "GATAD2B", "GCC2", "GDPD1", "GGCT", "GGCX", "GINS2", "GINS3", "GLO1", "GNAI2", "GNG5", "GOLGB1", "GOLIM4", "GSTZ1", "GYS1", "H1F0", "H2AFX", "H4C1*", "HADHB", "HDAC1", "HDAC2", "HGS", "HINT2", "HIST1H1C", "HIST1H1E", "HLTF", "HMGA1", "HMGB1", "HMOX1", "HMOX2", "HSP90AA1", "HSP90AB1", "HSPA8", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "JUP", "KDM1A", "KDSR", "KIF1A", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KMT2A", "KNTC1", "KPNA1", "KPNA3", "KTN1", "LAMTOR1", "LAMTOR2", "LCLAT1", "LETM1", "LIG1", "LIG3", "LYPLA1", "M6PR", "MANF", "MAP2K1", "MAP2K2", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MAVS", "MCCC2", "MCU", "ME2", "MECP2", "MED24", "MED25", "MFN2", "MIA3", "MIPEP", "MMGT1", "MOSPD2", "MPG", "MRPL12", "MRPL14", "MRPL17", "MRPL28", "MRPL38", "MRPL40", "MRPL45", "MRPL50", "MRPL58", "MRPL9", "MRPS10", "MRPS17", "MRPS23", "MRPS28", "MRPS35", "MRPS5", "MRRF", "MSN", "MTA1", "MTA2", "MTIF2", "MTOR", "MTX1", "NAMPT", "NCAPD3", "NCAPG", "NCSTN", "NDUFA11", "NDUFA5", "NDUFA8", "NDUFA9", "NDUFAF7", "NDUFB11", "NDUFB3", "NDUFS2", "NDUFS3", "NDUFS7", "NECAP1", "NECAP2", "NEFL", "NELFB", "NOP2", "NPTN", "NRBP1", "NUBPL", "NUDT12", "NUF2", "NUP188", "NUP58", "OCRL", "OGT", "ORC3", "OXA1L", "PABPC1", "PABPN1", "PAFAH1B2", "PAFAH1B3", "PARP2", "PDCD6", "PDHB", "PDK3", "PDS5B", "PDXK", "PFDN6", "PGRMC2", "PHAX", "PIGK", "PIN1", "PITPNA", "PKMYT1", "PLA2G15", "PLIN3", "PMPCA", "POLA1", "POLA2", "POLE", "POLR1A", "POLR1B", "POLR1C", "POLR2E", "PPM1F", "PPP1CA", "PPP2R1A", "PPP2R5D", "PPP3CA", "PRC1", "PRIM1", "PRIM2", "PRKACA", "PRKAG1", "PRKAR1A", "PSMB2", "PSMB6", "PSMC6", "PSMD10", "PSMD14", "PSMD3", "PSMD4", "PSME1", "PSME4", "PTCD3", "PTRH2", "PUM1", "PYCR1", "QKI", "RAB1A", "RAB3GAP2", "RAB5A", "RABGAP1", "RAC1", "RACGAP1", "RANBP9", "RAP1GDS1", "RASA1", "RBP1", "RDX", "RETSAT", "REXO2", "RHOG", "ROCK2", "RPA3", "RPL10A", "RPL12", "RPL13", "RPL22", "RPL23", "RPL23A", "RPL26", "RPL27", "RPL28", "RPL29", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL38", "RPL7", "RPL7A", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPRD1B", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS3A", "RPS6", "RPS7", "RPS8", "RPS9", "RPSA", "RUFY1", "RUVBL1", "SAP30BP", "SARNP", "SARS", "SCARB1", "SCD", "SEC11A", "SERPINB6", "SF3B4", "SGPL1", "SHMT2", "SHOC2", "SIN3A", "SLC1A5", "SLC25A10", "SLC25A15", "SLC25A26", "SLC25A32", "SLC29A1", "SLC30A5", "SLC35B2", "SLC3A2", "SLTM", "SMARCA4", "SMARCA5", "SMC2", "SNAP23", "SNAP29", "SNRPD1", "SNRPD3", "SNRPE", "SOAT1", "SOD2", "SPC25", "SPPL2A", "SRPRA", "SSBP1", "SSR1", "STAM", "STAT3", "STK4", "STMN1", "STRN", "STUB1", "SUCLG2", "SUN1", "SURF4", "SUZ12", "SYMPK", "TAB1", "TARS2", "TBCB", "TFRC", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TLN1", "TMEM87A", "TMPO", "TOMM22", "TOMM5", "TOR1AIP1", "TP53", "TRAP1", "TRAPPC11", "TRAPPC5", "TRIM25", "TTC26", "TTYH3", "TUBB2A", "TUBB4A", "TUBB4B", "TUBGCP2", "TUBGCP3", "TWF1", "TWF2", "TXNL1", "TXNRD1", "UBA2", "UBA3", "UBE2N", "UBE2S", "UGGT1", "UGP2", "UNC119B", "UNG", "UQCR10", "UQCRB", "UQCRQ", "USP33", "VARS2", "VCP", "VIM", "VPS26A", "VRK1", "VRK3", "WAPL", "YARS", "YARS2", "YKT6", "YME1L1", "YWHAH", "ZNF512B"]} \ No newline at end of file diff --git a/msigdb_wp/advanced/idx2term.json b/msigdb_wp/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..06c0dd6057fe50af45e6404623843a15c8a47617 --- /dev/null +++ b/msigdb_wp/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Electron transport chain oxphos system in mitochondria", "1": "Amyotrophic lateral sclerosis als", "2": "Nonalcoholic fatty liver disease", "3": "Epithelial to mesenchymal transition in colorectal cancer"} \ No newline at end of file diff --git a/msigdb_wp/advanced/plot_0.png b/msigdb_wp/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..3d3b709bbfc4e2086421d596ba06109168cfd1de --- /dev/null +++ b/msigdb_wp/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:baf6f54117d96446599b41dd952d8ad6d84c6aa2121ee139251ae757f2db9a27 +size 208619 diff --git a/msigdb_wp/advanced/plot_1.png b/msigdb_wp/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..dce74a38949783424ba814a23f80eb220a2da7b6 --- /dev/null +++ b/msigdb_wp/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:191cb7c45af786b3d4237490a515c35bc6ed94f07e4800ef6c34fd12732120c3 +size 198800 diff --git a/msigdb_wp/advanced/plot_2.png b/msigdb_wp/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..8da87b4d17a13ec0197708a9a6e98653e1fdfbbb --- /dev/null +++ b/msigdb_wp/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:adf266d6aadeeb532644f55d7e14e66d2acf2ee8cb6a27794094bc575f4c77cd +size 207583 diff --git a/msigdb_wp/advanced/plot_3.png b/msigdb_wp/advanced/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..2043ae16704ff1e33fc5abf8b5790a57488fefb1 --- /dev/null +++ b/msigdb_wp/advanced/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d3e546e7d5e4a4fdf25c11cb9959de83472d432a6e3ab63b750834412197146b +size 197531 diff --git a/msigdb_wp/basic/idx2term.json b/msigdb_wp/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..28f6d33a4dabfbd618a936846633ad1af394cb63 --- /dev/null +++ b/msigdb_wp/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Electron transport chain oxphos system in mitochondria", "1": "Amyotrophic lateral sclerosis als", "2": "Nonalcoholic fatty liver disease", "3": "Epithelial to mesenchymal transition in colorectal cancer", "4": "Cardiac hypertrophic response", "5": "Oxidative phosphorylation", "6": "Ras signaling", "7": "Adipogenesis", "8": "Met in type 1 papillary renal cell carcinoma", "9": "Il1 signaling pathway", "10": "Acute viral myocarditis", "11": "Mitochondrial complex i assembly model oxphos system", "12": "Tolllike receptor signaling pathway", "13": "Pi3kakt signaling pathway", "14": "Hepatitis b infection", "15": "Nephrotic syndrome", "16": "Retinoblastoma gene in cancer", "17": "Micrornas in cardiomyocyte hypertrophy", "18": "Ppar signaling pathway", "19": "Focal adhesion pi3kaktmtorsignaling pathway", "20": "Orexin receptor pathway", "21": "Nonsmall cell lung cancer", "22": "Ciliary landscape", "23": "Mapk signaling pathway", "24": "Tcell activation sarscov2", "25": "Tgfbeta signaling pathway", "26": "Vasopressinregulated water reabsorption", "27": "Integrinmediated cell adhesion", "28": "Fluoropyrimidine activity", "29": "Alzheimers disease and mirna effects", "30": "Alzheimers disease", "31": "Network map of sarscov2 signaling pathway", "32": "Oncostatin m signaling pathway", "33": "Parkinubiquitin proteasomal system pathway", "34": "Androgen receptor signaling pathway", "35": "Prolactin signaling pathway", "36": "Cytoplasmic ribosomal proteins", "37": "Neuroinflammation and glutamatergic signaling", "38": "Gastrin signaling pathway", "39": "Sudden infant death syndrome sids susceptibility pathways", "40": "Thyroid hormones production and peripheral downstream signaling effects", "41": "Nucleotide metabolism", "42": "Cori cycle", "43": "Glycolysis in senescence", "44": "Valproic acid pathway", "45": "Metabolic reprogramming in colon cancer"} \ No newline at end of file diff --git a/msigdb_wp/basic/plot_0.png b/msigdb_wp/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..b8baceab550d6d50365361e4f9cc07934fd72688 --- /dev/null +++ b/msigdb_wp/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3e4690a8f1a0f0ad2cd93b87e6866c7ac1e47f5df25b4acf74ecfd7b9032c1ca +size 147618 diff --git a/msigdb_wp/basic/plot_1.png b/msigdb_wp/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..09e9b932a5bc24d2cfb7c6bfdab8cbd610f18039 --- /dev/null +++ b/msigdb_wp/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:71d6adc006320f0b232917da9e51f0d9e35a6fb2825507983786f1a1682065dd +size 144188 diff --git a/msigdb_wp/basic/plot_10.png b/msigdb_wp/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..61a01e178eaa628712c6329f326ceded90f44761 --- /dev/null +++ b/msigdb_wp/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e31a129e62c08d114c61913a5b636624b4ef4f8207df27fe9538def5c662d947 +size 133347 diff --git a/msigdb_wp/basic/plot_11.png b/msigdb_wp/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..ce29dbf70a902a2c927be35bcf53ebbb74aa7b52 --- /dev/null +++ b/msigdb_wp/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b12dd82f4c3a616d8672f83822e95d91eb970299b045e8fc71a3dacccb7f7ff0 +size 139257 diff --git a/msigdb_wp/basic/plot_12.png b/msigdb_wp/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..6f01b3a4b64fc7e0701d8ee2b966ffa3388d7a86 --- /dev/null +++ b/msigdb_wp/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4414c6cb1b297628ff2993db3ab383cab9018fe5c2fffc552d45254fdcfb261e +size 139328 diff --git a/msigdb_wp/basic/plot_13.png b/msigdb_wp/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..d9b93da8aad341bfb2dd9c44277ed1bd83d2884d --- /dev/null +++ b/msigdb_wp/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:72122033f7b29d71aa0ac308f3a1662133951077d9de89e7109c828b5b08818a +size 134270 diff --git a/msigdb_wp/basic/plot_14.png b/msigdb_wp/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..886359baf0afc524bdfb478cc113518588283b95 --- /dev/null +++ b/msigdb_wp/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3fc5c6f78f485fda2e440603a8281fa2bb2edb77a210b8d0252f26f0f1301365 +size 140431 diff --git a/msigdb_wp/basic/plot_15.png b/msigdb_wp/basic/plot_15.png new file mode 100644 index 0000000000000000000000000000000000000000..f48bec41903ec65d0e057ddc4c9b12e9b30f736d --- /dev/null +++ b/msigdb_wp/basic/plot_15.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:83420332aee0b563a00d289fd4f5038b7d36f8df7224ccbd9b9d1f4b04a6ea09 +size 134954 diff --git a/msigdb_wp/basic/plot_16.png b/msigdb_wp/basic/plot_16.png new file mode 100644 index 0000000000000000000000000000000000000000..c79624728caabc7abc8ecba4e03e401c7644200d --- /dev/null +++ b/msigdb_wp/basic/plot_16.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9d54e3e8ab8d4935d93b33cb2503f335e1f92201f329c89dfe641e303d26d573 +size 145757 diff --git a/msigdb_wp/basic/plot_17.png b/msigdb_wp/basic/plot_17.png new file mode 100644 index 0000000000000000000000000000000000000000..1d709e1f772991fe47b8c4f346a1620d71ff27f5 --- /dev/null +++ b/msigdb_wp/basic/plot_17.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fbf2306d0937e4f397ae3bf0da9a1284653fa7960bf492d3661cdc1701d233c1 +size 143531 diff --git a/msigdb_wp/basic/plot_18.png b/msigdb_wp/basic/plot_18.png new file mode 100644 index 0000000000000000000000000000000000000000..519ee456f169a85dd58ac9208fbe1f3f2dcaf701 --- /dev/null +++ b/msigdb_wp/basic/plot_18.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c0bf10a798241d8bac4594fd6481f35daeec369ce373077109b50036a87750e1 +size 135286 diff --git a/msigdb_wp/basic/plot_19.png b/msigdb_wp/basic/plot_19.png new file mode 100644 index 0000000000000000000000000000000000000000..843ac55b17a61608eccad347881f4b998102c9b9 --- /dev/null +++ b/msigdb_wp/basic/plot_19.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:75dadf241665bcb38584f4dacdb275458cf829933dacad2c3396d305d61b0964 +size 150947 diff --git a/msigdb_wp/basic/plot_2.png b/msigdb_wp/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..0e41673094a89683dbff0372eb408a004d3af50e --- /dev/null +++ b/msigdb_wp/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:56421edc11cc52b3ba0b8dc30410694f41f2ba2b1e2157d6e121fa4934344142 +size 141974 diff --git a/msigdb_wp/basic/plot_20.png b/msigdb_wp/basic/plot_20.png new file mode 100644 index 0000000000000000000000000000000000000000..01ac233748991ba051e59c12477f0d3fc308ff47 --- /dev/null +++ b/msigdb_wp/basic/plot_20.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2dd4824a3b3945af32e9d30ab2f30026ff960504f69097b5c4de44c0d899df71 +size 146842 diff --git a/msigdb_wp/basic/plot_21.png b/msigdb_wp/basic/plot_21.png new file mode 100644 index 0000000000000000000000000000000000000000..c971600a9be8cedb9ea5eaa5716c28edf985cda3 --- /dev/null +++ b/msigdb_wp/basic/plot_21.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2ce4ff2302f41e08638c9d4ef8c181fe66f4d5dd72fb1c71e87f3f67d3cd23c2 +size 137934 diff --git a/msigdb_wp/basic/plot_22.png b/msigdb_wp/basic/plot_22.png new file mode 100644 index 0000000000000000000000000000000000000000..fb75939f82b1ce75c4ec00a2f9dee9033d5ab827 --- /dev/null +++ b/msigdb_wp/basic/plot_22.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c25eb20f4368d5cac4ac80464e27736fd9e27c5d76a2915661d6b35ba7ff83f8 +size 143995 diff --git a/msigdb_wp/basic/plot_23.png b/msigdb_wp/basic/plot_23.png new file mode 100644 index 0000000000000000000000000000000000000000..c26d043fc78aab56d222537409ed146a8583397e --- /dev/null +++ b/msigdb_wp/basic/plot_23.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:920fb9857404b866e765dfd5c2b8149b050a9c8dea9142cbc9589f9223830734 +size 140270 diff --git a/msigdb_wp/basic/plot_24.png b/msigdb_wp/basic/plot_24.png new file mode 100644 index 0000000000000000000000000000000000000000..ba207d7068809e75f3ef3665a042d6c611c17b2d --- /dev/null +++ b/msigdb_wp/basic/plot_24.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5f5f5d02bf864db6506d226c7954a19fbdcfc35641b3c1874083dad85002c895 +size 148062 diff --git a/msigdb_wp/basic/plot_25.png b/msigdb_wp/basic/plot_25.png new file mode 100644 index 0000000000000000000000000000000000000000..566c80621e65b7de0ad8d527bf75d0b881d294ce --- /dev/null +++ b/msigdb_wp/basic/plot_25.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5bee29146490f4550cc49eb89e689270e0cb6f9dc7daf20b8bbb03f53be846fb +size 151382 diff --git a/msigdb_wp/basic/plot_26.png b/msigdb_wp/basic/plot_26.png new file mode 100644 index 0000000000000000000000000000000000000000..e755fa4550429066b544d19fa38c1c71fe0c719a --- /dev/null +++ b/msigdb_wp/basic/plot_26.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3bd5bfa14d54ac25a2da54c0f82ee0c73963d20ce291573ad7e16cfba606d758 +size 150578 diff --git a/msigdb_wp/basic/plot_27.png b/msigdb_wp/basic/plot_27.png new file mode 100644 index 0000000000000000000000000000000000000000..4ef71a6925b186deffe726ddf5587c5c73072d15 --- /dev/null +++ b/msigdb_wp/basic/plot_27.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9ceb903d62c590f3189740072a53f683996abf65c350c7a54128a3022efd048d +size 147929 diff --git a/msigdb_wp/basic/plot_28.png b/msigdb_wp/basic/plot_28.png new file mode 100644 index 0000000000000000000000000000000000000000..6aeec87ce755a8d0a2bb914ea6e4853addb8fb8c --- /dev/null +++ b/msigdb_wp/basic/plot_28.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d385af8375419d7263f752096ab6eba47405dc346a06cfa49477066be9373713 +size 142762 diff --git a/msigdb_wp/basic/plot_29.png b/msigdb_wp/basic/plot_29.png new file mode 100644 index 0000000000000000000000000000000000000000..df64487157607661b2da7979aa14fa5f43685097 --- /dev/null +++ b/msigdb_wp/basic/plot_29.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e410fc0b9c7912aa437542ebf5242c49d59da3a705c6d803c3848bab322eddcb +size 153527 diff --git a/msigdb_wp/basic/plot_3.png b/msigdb_wp/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..b4f8e2dfa51d04a8ee1e5ae489867cd1d5e58062 --- /dev/null +++ b/msigdb_wp/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2f0e4311a45f8cb97b4df32f48df3de69e3b83f767b440c60597cac6660a827f +size 137066 diff --git a/msigdb_wp/basic/plot_30.png b/msigdb_wp/basic/plot_30.png new file mode 100644 index 0000000000000000000000000000000000000000..9e68b360b441e908f7cd75cd9730fa8c9ce0315f --- /dev/null +++ b/msigdb_wp/basic/plot_30.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:dcd0ee8d8c6db2955c32dc9907a037cabd8710d4a6cc0ddc481fe7f68e785567 +size 147955 diff --git a/msigdb_wp/basic/plot_31.png b/msigdb_wp/basic/plot_31.png new file mode 100644 index 0000000000000000000000000000000000000000..50d28886ddb42df68dc2c15bde7d0f74ee7da69a --- /dev/null +++ b/msigdb_wp/basic/plot_31.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e644b3fad2084336fbc230d65f81832be51a1d533e29baf5046ed2c8e9d4cb0e +size 149896 diff --git a/msigdb_wp/basic/plot_32.png b/msigdb_wp/basic/plot_32.png new file mode 100644 index 0000000000000000000000000000000000000000..f24acf951df179307728063c0897c920ef273be8 --- /dev/null +++ b/msigdb_wp/basic/plot_32.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:be9f534406976b07ed2cdcae5ee230da7e144b13b1e671049107c19713f17e3c +size 147659 diff --git a/msigdb_wp/basic/plot_33.png b/msigdb_wp/basic/plot_33.png new file mode 100644 index 0000000000000000000000000000000000000000..160bbc590e8a2e84c42035fc4206de5582ccbbab --- /dev/null +++ b/msigdb_wp/basic/plot_33.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a4be8938bdae4c70394452bc0cce6471d0652ecc41b57928cac0e16d6ce2e563 +size 153020 diff --git a/msigdb_wp/basic/plot_34.png b/msigdb_wp/basic/plot_34.png new file mode 100644 index 0000000000000000000000000000000000000000..2c5d145f026ee6d58a94b7232c09ebab90992b89 --- /dev/null +++ b/msigdb_wp/basic/plot_34.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bd831d8df06684fc156b61848219d1370ed60e54c875f31f7e0dd94680fd3f6c +size 147396 diff --git a/msigdb_wp/basic/plot_35.png b/msigdb_wp/basic/plot_35.png new file mode 100644 index 0000000000000000000000000000000000000000..ff82e8aa961e70745a2382c12c36cc877b4ccd2c --- /dev/null +++ b/msigdb_wp/basic/plot_35.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4e604ba7b3513265061bc17be84e4fc73cf2bb2ef082b78b3bf8bcf2a7352128 +size 150905 diff --git a/msigdb_wp/basic/plot_36.png b/msigdb_wp/basic/plot_36.png new file mode 100644 index 0000000000000000000000000000000000000000..5b02cdaa8ceeecfef049bdf80e8ca69401872b71 --- /dev/null +++ b/msigdb_wp/basic/plot_36.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b22df2849fa8393bca3f77e878c4aeef26e4f4a4ef39b2f42a7c15a43facc90a +size 152878 diff --git a/msigdb_wp/basic/plot_37.png b/msigdb_wp/basic/plot_37.png new file mode 100644 index 0000000000000000000000000000000000000000..b890891b36a7cf2cb9e2d44ecc77d9f0e25b28ea --- /dev/null +++ b/msigdb_wp/basic/plot_37.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4ef7221624753f9d8378abbbd999588ba7f585b3abda758225219122edee83b5 +size 153448 diff --git a/msigdb_wp/basic/plot_38.png b/msigdb_wp/basic/plot_38.png new file mode 100644 index 0000000000000000000000000000000000000000..f5e1662273a1d77a768116e309322c90414a28c7 --- /dev/null +++ b/msigdb_wp/basic/plot_38.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b1ca19f9c24b452873e5e5e2106e6c3f49fe265e7aceeb516a8b7a629ecc4dd6 +size 152934 diff --git a/msigdb_wp/basic/plot_39.png b/msigdb_wp/basic/plot_39.png new file mode 100644 index 0000000000000000000000000000000000000000..d1aa37ef9d8d62fe858642a19852e878c3f283fe --- /dev/null +++ b/msigdb_wp/basic/plot_39.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e7c96db9aded9c780464b5ad917184365d623668614675bcf8c8c9a10ca3aae2 +size 157812 diff --git a/msigdb_wp/basic/plot_4.png b/msigdb_wp/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..f4121db4ae0c80e195966126c92c8e2d39f19641 --- /dev/null +++ b/msigdb_wp/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4f9350d39142050d264bb35957364f206a534e167212854754cf784cdace3ef7 +size 136615 diff --git a/msigdb_wp/basic/plot_40.png b/msigdb_wp/basic/plot_40.png new file mode 100644 index 0000000000000000000000000000000000000000..52d25b4f486c181b66f9611e07bd8be03bdbeadd --- /dev/null +++ b/msigdb_wp/basic/plot_40.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:987b42182bc527ab299a11774963c76ca5e34627fa41cc417796de2f9f29dce2 +size 152692 diff --git a/msigdb_wp/basic/plot_41.png b/msigdb_wp/basic/plot_41.png new file mode 100644 index 0000000000000000000000000000000000000000..c2f669fe3ba11c9be73162a7738af0ccd66dc600 --- /dev/null +++ b/msigdb_wp/basic/plot_41.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d283d7a7b6dc14f230b452ef0a78fbb16af24f4b0e50030c22a39843d6d85b0a +size 144265 diff --git a/msigdb_wp/basic/plot_42.png b/msigdb_wp/basic/plot_42.png new file mode 100644 index 0000000000000000000000000000000000000000..e9501481dc76cfd178f2477a2ea418f42510058e --- /dev/null +++ b/msigdb_wp/basic/plot_42.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8a4c7b88c3c3614f60ba238a6ce80cea08104bc3ae0cfd301be4d89e249b574d +size 136855 diff --git a/msigdb_wp/basic/plot_43.png b/msigdb_wp/basic/plot_43.png new file mode 100644 index 0000000000000000000000000000000000000000..a1348576c7ee7856ed4932b6399c341d4213af3d --- /dev/null +++ b/msigdb_wp/basic/plot_43.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3b2e5f7a24695ddee1c106daad43065e7e949afef8bef3def102ba7edcacb8b9 +size 146381 diff --git a/msigdb_wp/basic/plot_44.png b/msigdb_wp/basic/plot_44.png new file mode 100644 index 0000000000000000000000000000000000000000..f569af6fc4cc17f6098ff30634b543ce10342a76 --- /dev/null +++ b/msigdb_wp/basic/plot_44.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:61fd83a74443913806b3ef66358f611b1ebdc74e17cad75d63218c9fc8bb980a +size 143722 diff --git a/msigdb_wp/basic/plot_45.png b/msigdb_wp/basic/plot_45.png new file mode 100644 index 0000000000000000000000000000000000000000..ee8ae983b8cf92b56a2ab4ed5814bd60fe2f95a0 --- /dev/null +++ b/msigdb_wp/basic/plot_45.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7af81dcfef534dc624cac3a2eb9a5046bb4ea4a6fc0613b8b99cb80d13fe76a7 +size 157234 diff --git a/msigdb_wp/basic/plot_5.png b/msigdb_wp/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..515c47e034d407d62700c1fb6dff06bcb85c58da --- /dev/null +++ b/msigdb_wp/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0820f870f2e6641562dd78dc72a08bd591a10d8dddfa050499bad24aa19a99d2 +size 133960 diff --git a/msigdb_wp/basic/plot_6.png b/msigdb_wp/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..eb2cb9a3145c0348bbbaf0f5f1fc97a4ae0fe054 --- /dev/null +++ b/msigdb_wp/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:300eeeb3ee61eb52e32948c165cb9bdf83c7201edccca340cd8f05fc9e84b49a +size 130890 diff --git a/msigdb_wp/basic/plot_7.png b/msigdb_wp/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..a1ad6e4612eab17c473fd04acee264c9f6d1f7de --- /dev/null +++ b/msigdb_wp/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:09104dd3bb1bb1b6383fcb82c80a294d55e4148ee9cd461bc489fa2efb7f83cd +size 132058 diff --git a/msigdb_wp/basic/plot_8.png b/msigdb_wp/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..92b036cf4d47878192c2d486179ec86989a2413c --- /dev/null +++ b/msigdb_wp/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1f915685386333554689f71b48914039dc5669de48b662b8f91ba7bd0212e5f9 +size 135319 diff --git a/msigdb_wp/basic/plot_9.png b/msigdb_wp/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..5bbeb4d6571ca0d4efb3b1cd71ac0eb8799d8bdd --- /dev/null +++ b/msigdb_wp/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:295aa80ffec07cfe3ebaa78116e157b39ca5452841ea932af6d5bfc6ac3dd01f +size 133612 diff --git a/msigdb_wp/consensus.joblib b/msigdb_wp/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..97a28f09a2dacd66998899e6b01cf02be9344a7c --- /dev/null +++ b/msigdb_wp/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:86bd0bc3267da687fec0f08afa3be8e0c84f4fd99f92c025da454a8461e74d7e +size 91467 diff --git a/msigdb_wp/df_merge.tsv b/msigdb_wp/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..79e40c67ec8351701167b7a96abdbfe3058a996f --- /dev/null +++ b/msigdb_wp/df_merge.tsv @@ -0,0 +1,8 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Electron transport chain oxphos system in mitochondria 20 47 2.588741287417641 0.0096327435091279 17.57766990291262 50.45631067961165 1.00621396752225 0.3125021459260491 7.648293572467493 4.538458527560961 1.9412236823915887 0.3642771965747766 1.0 0.3503528550879276 0.0098339838253012 0.0055502813262233 0.0012235128374341 +Amyotrophic lateral sclerosis als 8 13 2.545479719681042 0.0109127702622775 2.7305825242718447 9.96116504854369 0.4205357655297272 0.5708808425163486 1.655451908056762 1.5928988662189754 0.7372675469681915 0.2961491189852112 1.0 1.0 0.0328837758174392 0.0057168779164092 9.285683004496466e-06 +Nonalcoholic fatty liver disease 18 48 2.462813426716408 0.0137851628217415 14.446601941747574 49.78883495145631 0.8140299356769594 0.4039994838731682 5.918094936421778 5.382150615191258 1.5259550974793896 0.3817978315095583 1.0 1.0 0.1103594043165888 0.0028834529050708 0.0009393345882195 +Oxidation by cytochrome p450 2 5 2.174819827740836 0.0296436206490424 2.3179611650485437 5.422330097087379 1.262256455948566 0.1900711291682963 1.161003800051733 0.6764315332620536 1.214909583878196 0.2447393771863318 1.0 0.0016377422378922 0.0061398538588971 0.0030929731790992 0.0215291267260604 +Base excision repair 3 15 2.097316909305123 0.0359655309834314 6.152912621359223 16.800970873786408 -0.2879657493108331 0.5108252748349887 3.4030848743849873 2.456257914165212 1.0291967772689437 0.3266538784465854 1.0 0.1444128696349771 0.2637098090419308 0.0071674542029393 0.0700819952928245 +Tnfrelated weak inducer of apoptosis tweak signaling pathway 4 11 2.019739550549477 0.043410410322914 3.817961165048544 10.87864077669903 -0.1233546342429627 0.5812659212421455 2.6084939147612007 2.9162800645081983 0.8413059529803897 0.3016323404833174 1.0 1.0 0.2637098090419308 0.0071674542029393 0.0189589601631659 +Epithelial to mesenchymal transition in colorectal cancer 6 17 2.01786732655654 0.0436050806970143 6.184466019417476 20.6504854368932 -0.407655820560729 0.5763629417553673 3.4808702539125864 3.392478081188044 0.791702703815651 0.3015813162055066 1.0 1.0 0.6020385613857171 0.413420225777224 0.1927232511082809 diff --git a/msigdb_wp/metrics.json b/msigdb_wp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..2f2b602c2a3dc21ebed2bfa8971b9a423c601e98 --- /dev/null +++ b/msigdb_wp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2772, + "annotations_size": 593, + "title": "Average number of proteins per term", + "value": 10.165261382799326 +} \ No newline at end of file diff --git a/msigdb_wp/paths.json b/msigdb_wp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..15bbda9394f5142c1bcf6083d7ae3d18b7f2a4f5 --- /dev/null +++ b/msigdb_wp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_wp/fragment/C321/C321_val_log2fc"} \ No newline at end of file diff --git a/msigdb_wp/result.tsv b/msigdb_wp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..457475179c499579fa231f789ebfa8d2766cb171 --- /dev/null +++ b/msigdb_wp/result.tsv @@ -0,0 +1,245 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Electron transport chain oxphos system in mitochondria 0.5480914965163497 2.5887412874176414 0.0096327435091279 0.9967849328202172 0.1422057201366264 47 P14927,P00846,O75947,P51970,O14949,P13073,Q9UDW1,O75489,P15954,Q16795,P56385,Q9UII2,Q16718,P05141,P06576,O75306,P09669,P36542,O43676,O75251 20 +Amyotrophic lateral sclerosis als 0.7841144624798462 2.545479719681042 0.0109127702622775 0.9985068115229236 0.1504947154774555 13 P07197,P07196,Q08209,Q9BUN8,P36507,P42574,Q9UER7,P20339 8 +Nonalcoholic fatty liver disease 0.5317977445258008 2.462813426716408 0.0137851628217415 0.9997338548926952 0.1777087294194078 48 P13073,O75306,P09669,P51970,Q9UDW1,P31749,O75489,P15954,P14927,Q86Y39,P31751,O43676,Q16795,P42574,Q16718,Q9NX14,O14949,P54619 18 +Oxidation by cytochrome p450 0.925575007056068 2.174819827740836 0.0296436206490424 0.9999999822073614 0.3140502269957009 5 Q16850,Q6UW02 2 +Estrogen receptor pathway 0.8776173285198547 2.174636631161973 0.0296573570181437 0.9999999823560978 0.3140502269957009 2 Q15067 1 +Base excision repair 0.6599203762525024 2.097316909305123 0.0359655309834314 0.9999999996311164 0.3417975959113095 15 P18858,P13051,Q07864 3 +Tnfrelated weak inducer of apoptosis tweak signaling pathway 0.7309850253773681 2.0197395505494775 0.043410410322914 0.999999999996282 0.3800610825211027 11 P42574,O43318,P31751,P31749 4 +Epithelial to mesenchymal transition in colorectal cancer 0.6303066240519691 2.01786732655654 0.0436050806970143 0.9999999999967047 0.3800610825211027 17 Q8TB37,P31749,P14923,P31751,P36507,P15924 6 +Cardiac hypertrophic response 0.6913842242341484 1.9525158891902232 0.0508769863756537 0.9999999999999644 0.3993651753329991 12 O43318,P31749,P31751,Q08209,P36507 5 +Oxidative phosphorylation 0.5539291812161149 1.9410835204299943 0.0522481476039864 0.9999999999999848 0.3993651753329991 27 O75947,O75306,P51970,O75489,P19404,Q86Y39,O95182,Q16795,O75251,P00846,P56385,Q16718,P56556,P06576 14 +Microtubule cytoskeleton regulation 0.6357099609391549 1.9332631219081575 0.053203792329354 0.9999999999999916 0.3993651753329991 14 Q7KZI7,P40763,P16949,P31749 4 +Ampactivated protein kinase ampk signaling 0.6054600320687428 1.7990163410079292 0.0720160958520188 1.0 0.4551428236110016 15 Q9Y376,P14635,P31749 3 +Ras signaling 0.5288732902204524 1.7688081444698265 0.0769258971405577 1.0 0.4655123425075891 27 Q96KP1,P20936,P31749,P31751,Q9NWH9,Q13043,P36507,P20339 8 +Relationship between inflammation cox2 and egfr 0.8198903493041283 1.7687762994674694 0.0769312134329573 1.0 0.4655123425075891 5 P31749 1 +Metapathway biotransformation phase i and ii 0.5389299508826775 1.7035345870541574 0.0884680710702943 1.0 0.4852200044705002 22 Q6UW02 1 +Il17 signaling pathway 0.8021199857430227 1.6990372963561924 0.0893121565286187 1.0 0.4852200044705002 5 O43318,P31749 2 +Adipogenesis 0.6154991190353262 1.6913793181960437 0.0907643797298822 1.0 0.4852200044705002 13 O75844,Q16822,P40763,P43490,P17096 5 +Signal transduction through il1r 0.7975792879001249 1.6811585812320695 0.0927321161920651 1.0 0.4852200044705002 5 Q9BQ95,O43318,Q15750 3 +Vitamin a and carotenoid metabolism 0.794512027728981 1.6690684168377496 0.0951038216324549 1.0 0.4852200044705002 5 P09455 1 +Dna damage response only atm dependent 0.5576097210283979 1.6440757525507783 0.1001605558255529 1.0 0.5033492339368889 18 O43318,Q16822,P31749 3 +T cell receptor and costimulatory signaling 0.7867158827940187 1.6382925909857828 0.1013606725004685 1.0 0.5050998217880491 5 P20936,P31749 2 +Kisspeptinkisspeptin receptor system in the ovary 0.7651117308720414 1.6291634318283117 0.1032784259629282 1.0 0.5062178397277232 6 P31751,P31749 2 +Met in type 1 papillary renal cell carcinoma 0.5468114368791526 1.626893043395631 0.1037598157173123 1.0 0.5062178397277232 19 P31749,Q9NWH9,Q14241,P31751,P36507 5 +Il1 signaling pathway 0.5779786254326691 1.6171156985903632 0.1058533088132169 1.0 0.5062178397277232 14 O43318,P31749,Q15750,Q9BQ95,P36507,P61088 6 +Chromosomal and microsatellite instability in colorectal cancer 0.5559732182554527 1.5903893404292049 0.1117470715913864 1.0 0.5190907101858787 17 Q96KP1,P31751,P31749 3 +Ethanol metabolism production of ros by cyp2e1 0.7487364620938604 1.5887552702452388 0.1121156553518822 1.0 0.5190907101858787 2 P36507 1 +Intracellular trafficking proteins involved in cmt neuropathy 0.7548749430454038 1.5875339149338448 0.112391772037564 1.0 0.5190907101858787 6 P04792,P20337,P07196,O95140 4 +Acute viral myocarditis 0.554764316653023 1.5833239149491536 0.1133476547941882 1.0 0.5190907101858787 17 P20936,P31749,P78310,P11940,P42574 5 +Eukaryotic transcription initiation 0.6603854172859842 1.575086280544278 0.1152365303665323 1.0 0.5197299003993061 10 O15160,P18074,P19388,Q9H9Y6 4 +Mitochondrial complex i assembly model oxphos system 0.5187677067264473 1.5731231813415576 0.1156902982339096 1.0 0.5197299003993061 22 Q7L592,P51970,Q8TB37,O75489,Q9BQ95,O43676,Q9NX14 7 +Vitamin b12 metabolism 0.7657028722376612 1.5550361145694638 0.1199374684478788 1.0 0.5300516165429081 5 P04179,Q8WTV0 2 +Tolllike receptor signaling pathway 0.6109731836664807 1.5482452060059964 0.1215632712476146 1.0 0.5300516165429081 12 O43318,P31749,Q15750,P31751,P36507 5 +Nrp1triggered signaling pathways in pancreatic cancer 0.6489283996385743 1.521094361311844 0.1282361592913461 1.0 0.5470794421566062 10 Q9NWH9,P31751,P31749 3 +Extracellular vesiclemediated signaling in recipient cells 0.8806247230113959 1.5032872687212842 0.1327649817141822 1.0 0.5583100025276005 4 P31749 1 +Kennedy pathway from sphingolipids 0.8784303462055423 1.4952400800919463 0.1348517968041573 1.0 0.5587312084488101 4 P35790 1 +Mrna protein and metabolite inducation pathway by cyclosporin a 0.7270758122743652 1.4884941799201168 0.1366206158938911 1.0 0.5587312084488101 2 P08195 1 +Oxidative stress response 0.7449898063014273 1.4725867606910137 0.1408624968454312 1.0 0.5677024593943424 5 P04179,Q16881,P09601 3 +Regulation of actin cytoskeleton 0.4625364609332474 1.4552134706300934 0.1456101727748335 1.0 0.5756455497031754 32 Q9UQB8,P26038,P36507 3 +Pi3kakt signaling pathway 0.4433109462548781 1.435390820520871 0.1511757603180719 1.0 0.5869250697865735 35 P31749,Q16822,Q9NWH9,P31751,P36507 5 +Wntbetacatenin signaling pathway in leukemia 0.8507071791010068 1.3934320027387934 0.1634891938213969 1.0 0.6168393101370822 4 P31749 1 +Complement system in neuronal development and plasticity 0.6604922416075498 1.3888707930820257 0.1648720433086348 1.0 0.6168393101370822 8 Q7KZI7 1 +Fas ligand pathway and stress induction of heat shock proteins 0.5323021330971801 1.3871632446823994 0.1653919904077505 1.0 0.6168393101370822 15 P04792,O43318,P42574 3 +Nucleotide excision repair 0.5063697724522644 1.378918789863261 0.1679197941407433 1.0 0.6209897374607131 19 P18858,P35244 2 +Hepatitis b infection 0.4765981352441508 1.352568032283468 0.1761936708918527 1.0 0.637090529505297 25 O43318,Q15750,P31749,P31751,P40763,P36507,P42574 7 +Selenium micronutrient network 0.6234015824596851 1.3085288966587272 0.1906939799853071 1.0 0.6612952441310284 9 P04179,Q8WTV0 2 +Regucalcin in proximal tubule epithelial kidney cells 0.6422799574072084 1.3084019534592664 0.1907370104136629 1.0 0.6612952441310284 8 Q8NE86,P31749 2 +Sphingolipid pathway 0.6150568146301882 1.270289033815596 0.2039816929805935 1.0 0.6671803339502221 9 Q06136,Q9Y5P4 2 +Transcription cofactors ski and skil protein partners 0.8170324334285438 1.2696271819219391 0.2042174622526396 1.0 0.6671803339502221 4 Q96ST3 1 +Egfr tyrosine kinase inhibitor resistance 0.510008137762322 1.2601406736710656 0.2076186197925498 1.0 0.6671803339502221 15 Q9NWH9,P36507,P31751,P31749 4 +Nocgmppkg mediated neuroprotection 0.8140980819052384 1.258844568612071 0.2080864787112517 1.0 0.6671803339502221 4 P07196 1 +Cell migration and invasion through p75ntr 0.6886522335232291 1.2471436983301432 0.2123448125740239 1.0 0.6711858090619359 5 P31751,P31749 2 +Nephrotic syndrome 0.5468392805914253 1.219003584618924 0.2228428319501585 1.0 0.68796561155015 12 O75844,P54577,Q9Y5K6,Q9NQW6,P52565 5 +Resistin as a regulator of inflammation 0.6436353174666666 1.21899858810763 0.2228447283679824 1.0 0.68796561155015 7 P31751,P31749 2 +Retinoblastoma gene in cancer 0.3947049772458895 1.198249904806628 0.2308197424700795 1.0 0.6963751395180294 45 Q96ST3,P00374,Q14527,P09455,P35244,P14635,Q07864 7 +Ranklrank signaling pathway 0.5025719811138585 1.1952466456176811 0.231990678773323 1.0 0.6963751395180294 14 O43318,P31751,P31749,Q15750 4 +Micrornas in cardiomyocyte hypertrophy 0.4757343176360872 1.189844459761829 0.2341075313944225 1.0 0.6963751395180294 19 Q15750,Q16539,P31749,P31751,Q08209,P40763,P36507 7 +Estrogen signaling pathway 0.6530629945974169 1.1696029923564917 0.2421607725781855 1.0 0.7042692181748196 6 Q16539,P17612,P31749 3 +Synaptic signaling pathways associated with autism spectrum disorder 0.5915100472436319 1.1623996241803864 0.2450731758826485 1.0 0.7089189916995638 9 P31751,P31749 2 +Ppar signaling pathway 0.487737776621356 1.156411926997846 0.2475127053510655 1.0 0.7116552711561789 16 Q15067,O15254,Q16822,Q01469,P23786 5 +Epo receptor signaling 0.5888258466399875 1.150112885288987 0.2500973799417576 1.0 0.7130180110839532 9 P20936,P36507,P31749 3 +Mirnas involvement in the immune response in sepsis 0.7830153694101687 1.1448411828797695 0.2522749521502732 1.0 0.7157849120818757 4 O43318,Q15750 2 +Familial partial lipodystrophy fpld 0.6029972495192514 1.134724615759506 0.2564907201575535 1.0 0.7242809383496629 8 O75844 1 +Sterol regulatory elementbinding proteins srebp signaling 0.4371610214339511 1.1252277616231108 0.2604925319009874 1.0 0.7318489779112949 27 Q16850,Q8WTV0 2 +Hostpathogen interaction of human coronaviruses apoptosis 0.7748204767082034 1.1148843697455448 0.2648999754914634 1.0 0.7318489779112949 4 P42574,P31749 2 +Focal adhesion pi3kaktmtorsignaling pathway 0.4037759119372626 1.1121516496504906 0.266072952569319 1.0 0.7318489779112949 35 P31749,Q9Y376,Q9NWH9,P31751,P36507 5 +Apoptosisrelated network due to altered notch3 in ovarian cancer 0.5258412573467888 1.1109975077421312 0.2665694220679278 1.0 0.7318489779112949 12 P31749 1 +Embryonic stem cell pluripotency pathways 0.543865077698904 1.108438724079355 0.2676723887972001 1.0 0.7318489779112949 11 P36507,P31751,P31749 3 +Cholesterol biosynthesis with skeletal dysplasias 0.6381020966073809 1.1081203849424637 0.2678098283419072 1.0 0.7318489779112949 6 Q16850 1 +Chemokine signaling pathway 0.4460480450918668 1.086979102243648 0.2770460454024033 1.0 0.7501749083270555 21 P63218,P04899,P31751,P31749 4 +Farnesoid x receptor pathway 0.6368231046931367 1.071320238893302 0.2840254626734064 1.0 0.758380100883864 2 Q13451 1 +Hippo signaling regulation pathways 0.475897704876671 1.065895840481268 0.2864707295075641 1.0 0.758380100883864 15 P04899,Q13043,Q9NWH9 3 +Neural crest cell migration during development 0.6251693207791617 1.0551112315550786 0.2913744558533304 1.0 0.761167631370154 6 P31751,P31749 2 +Neural crest cell migration in cancer 0.6251693207791617 1.0551112315550786 0.2913744558533304 1.0 0.761167631370154 6 P31751,P31749 2 +Metabolism of spingolipids in er and golgi apparatus 0.7706125101887362 1.038488099123689 0.2990428730082353 1.0 0.7615691360047198 3 Q06136 1 +Corticotropinreleasing hormone signaling pathway 0.4561826165225983 1.0341091635106383 0.301085132857362 1.0 0.7615691360047198 18 P14923,P04899,P31749 3 +Agerage pathway 0.4588670869866879 1.0183702647308548 0.3085020277981831 1.0 0.768498016668745 17 P26038,P42574,P40763,P31749 4 +Transcription factors regulate mirnas related to cardiac hypertrophy 0.7481438014788904 1.01783448134995 0.3087566223701574 1.0 0.768498016668745 4 P31751,P31749 2 +Cholesterol biosynthesis pathway 0.4890904025314584 1.0157847162948672 0.3097319156556999 1.0 0.768498016668745 13 Q16850 1 +Dna mismatch repair 0.4505709001660587 1.0004835812892463 0.3170765394181289 1.0 0.7834432828122937 18 P18858,P35244 2 +Vitamin d in inflammatory diseases 0.7556584991696469 0.9843526896071187 0.3249421312092622 1.0 0.797125952921476 3 Q08209 1 +Male infertility 0.4529339329398052 0.9836194353235914 0.3253026654418165 1.0 0.797125952921476 17 P04179,P17096,Q15165,P62805 4 +Hepatocyte growth factor receptor signaling 0.4823953786809207 0.9801523330873834 0.3270109297647683 1.0 0.797745947459927 13 P20936,Q9NWH9,P36507 3 +4hydroxytamoxifen dexamethasone and retinoic acids regulation of p27 expression 0.5497929269811578 0.9722878637120296 0.3309073597816747 1.0 0.797745947459927 9 P31749 1 +S1p receptor signal transduction 0.5474659215860986 0.9617630899634608 0.3361686226886573 1.0 0.797745947459927 9 P04899,P31751,P31749 3 +Hijack of ubiquitination by sarscov2 0.6008405621542603 0.955954988896643 0.3390949755311518 1.0 0.797745947459927 6 Q15369,Q8TBC4,Q13951 3 +Lipid metabolism pathway 0.5121377129479191 0.9527696385119389 0.3407068007136267 1.0 0.797745947459927 11 P17612,P54619,P31751,P31749 4 +Hepatitis c and hepatocellular carcinoma 0.5099909856074244 0.94231218708978 0.3460328304475311 1.0 0.797745947459927 11 P42574,P40763,P31749 3 +Orexin receptor pathway 0.4567050365716029 0.9389631924037724 0.3477496425956672 1.0 0.797745947459927 14 P55145,P11177,Q9Y2Z4,Q13595,P31350,P17096 6 +Leptininsulin signaling overlap 0.7422340035477591 0.936083235397632 0.3492303339097593 1.0 0.797745947459927 3 P31749 1 +Nonsmall cell lung cancer 0.439467999200158 0.9342402053469546 0.3501800006951194 1.0 0.797745947459927 18 P31749,P31751,P36507,P42574,Q13043 5 +Hematopoietic stem cell gene regulation by gabp alphabeta complex 0.605415162454869 0.9289381717946192 0.3529211292598377 1.0 0.797745947459927 2 P26358 1 +Hair follicle development cytodifferentiation part 3 of 3 0.6050541516245441 0.9273189476382472 0.3537609594511699 1.0 0.797745947459927 2 Q9BZE4 1 +Il6 signaling pathway 0.489707871487099 0.9265366037531064 0.3541671837583537 1.0 0.797745947459927 12 O43318,P36507,P31749 3 +Burn wound healing 0.5395257449237886 0.9259438234661664 0.35447517520067 1.0 0.797745947459927 9 P31749 1 +Mitochondrial complex iii assembly 0.5228712592127127 0.9240780464200332 0.3554456824803702 1.0 0.797745947459927 10 P14927,Q9UDW1,Q9Y276 3 +Il7 signaling pathway 0.5735502014817848 0.9220606818304816 0.3564969242443181 1.0 0.797745947459927 7 P36507,P31749 2 +Tnfalpha signaling pathway 0.4300240976285135 0.9095034776320762 0.3630844229613219 1.0 0.8010549618030838 19 O43318,P31749 2 +Endometrial cancer 0.485985751767323 0.9077172755918356 0.3640276142331533 1.0 0.8010549618030838 12 P31751,P31749 2 +Type 2 papillary renal cell carcinoma 0.587140872210755 0.9005809863556773 0.3678111477317485 1.0 0.8048413675458557 6 Q15369,P07954,O60610 3 +Interleukin1 il1 structural pathway 0.510929743435799 0.8685032126556753 0.3851189143322568 1.0 0.8276011632924143 10 O43318,P36507,Q15750 3 +Peroxiredoxin 2 induced ovarian failure 0.7059248554913043 0.8664985978417172 0.3862167949664878 1.0 0.8276011632924143 4 P42574,Q9UGN5,P32119 3 +Follicle stimulating hormone fsh signaling pathway 0.5414897718735989 0.8658251757086493 0.3865860408634043 1.0 0.8276011632924143 8 Q16539,P17612,P62753,P31749 4 +Hypertrophy model 0.589169675090248 0.8565667818708748 0.3916843505443883 1.0 0.8354993520605118 2 P06730 1 +Ciliary landscape 0.3123889088216091 0.8463309606641362 0.3973681407933185 1.0 0.8421329821119701 90 Q9Y312,Q13868,P07196,P52565,A5YKK6,P10619,Q96A65,Q9NQ48,Q96KP1,Q16795,O95721,Q16718,P62333,P61962,Q96PK6,P07197,Q06265,P09669,A0AVF1,O15173,P56545,Q9HDC9,Q96S59,Q8TAG9,P08579 25 +Regulatory circuits of the stat3 signaling pathway 0.5198989443136449 0.8381564485011672 0.4019428432049081 1.0 0.8421329821119701 9 Q16539,P40763,P16949 3 +Folate metabolism 0.4874444127629234 0.8333560616890087 0.4046439472618974 1.0 0.8421329821119701 11 P00374,Q8WTV0 2 +Mapk signaling pathway 0.3542386984786365 0.8308300257533615 0.4060696579230629 1.0 0.8421329821119701 39 P20936,O43318,P31749,Q15750,Q9BQ95,P31751,P04792,Q08209,P36507,P42574,Q9UER7,Q13043,P16949 13 +Tcell activation sarscov2 0.4330981628518369 0.8256200843275178 0.4090196383468993 1.0 0.8421329821119701 15 P42771,P31749,O95999,P36507,Q9H1B7,P42345,Q02750 7 +Tgfbeta signaling pathway 0.3800248980854992 0.8249487004381714 0.4094007157704331 1.0 0.8421329821119701 32 O43318,Q15750,P31749,Q96ST3,Q9NWH9,P36507 6 +Vasopressinregulated water reabsorption 0.4323304520116767 0.821379874811498 0.4114299233046636 1.0 0.8421329821119701 15 Q9UJW0,Q14204,P52565,O43237,P17612,P20339 6 +Integrinmediated cell adhesion 0.41528083776796 0.8206674942057166 0.4118356910834255 1.0 0.8421329821119701 19 O75116,P31749,Q9Y490,P31751,Q15942,P36507,Q02750,P07384 8 +Fluoropyrimidine activity 0.4512559554022518 0.8163290530796011 0.414311962016626 1.0 0.8442852009479699 13 P00374,Q99808,Q9BZX2,O15439,P31350,P18074 6 +Regulation of wnt bcatenin signaling by small molecule compounds 0.5783393501805005 0.8089536518219997 0.4185418063946278 1.0 0.8499838739452543 2 P35222 1 +Insulin signaling in adipocytes diabetic condition 0.6861791685968385 0.7971205004660713 0.4253810513020768 1.0 0.8579964742249372 4 P31751,P62753 2 +Insulin signaling in adipocytes normal condition 0.6861791685968385 0.7971205004660713 0.4253810513020768 1.0 0.8579964742249372 4 P31751,P62753 2 +Target of rapamycin tor signaling 0.4934800572919249 0.7882106663805474 0.430573491057763 1.0 0.864945644123768 10 P54619,P31749 2 +Notch signaling pathway 0.4765344830122658 0.7813528560165418 0.434594990747303 1.0 0.864945644123768 11 P40763,P31749 2 +Nucleotide excision repair in xeroderma pigmentosum 0.38326877702903 0.7680031262838264 0.4424853275634794 1.0 0.869388197163103 28 P18858,P35244 2 +Alzheimers disease and mirna effects 0.3139505273479835 0.7517233020708586 0.4522174741888842 1.0 0.8774855769699645 79 P55036,O00487,P31749,P49721,P31751,Q8NE86,Q08209,O95197,P36507,P42574 10 +Proximal tubule transport 0.5001896996463029 0.7514136567862106 0.4524037462790686 1.0 0.8774855769699645 9 O15439,P21283,P08195 3 +Tcell antigen receptor tcr pathway during staphylococcus aureus infection 0.4385466732505622 0.7507546700640354 0.4528003145915837 1.0 0.8774855769699645 13 O43318,P31749 2 +G1 to s cell cycle control 0.3869186661031002 0.7467378217988402 0.4552218346421763 1.0 0.8793047164260931 25 P35244,P14635 2 +Cannabinoid receptor signaling 0.560500703138484 0.7423036925351538 0.4579033550953273 1.0 0.8816126284789906 5 Q16539,P17612 2 +Alzheimers disease 0.3142050743395959 0.739376482764584 0.4596784184962517 1.0 0.8821660264345542 78 P55036,O00487,P31749,P49721,P31751,Q8NE86,Q08209,O95197,P36507,P42574 10 +Calcium regulation in cardiac cells 0.3896072216258258 0.7349129426186906 0.4623925155208384 1.0 0.8826552610529936 22 P04899,Q9Y3B8 2 +Kallmann syndrome 0.5567911636394616 0.7282794716356985 0.466442526063072 1.0 0.8841641224485963 5 P31749 1 +Vitamin d metabolism 0.5595667870036047 0.7278856430134661 0.4666835924560044 1.0 0.8841641224485963 2 P38435 1 +Network map of sarscov2 signaling pathway 0.3843495184868596 0.7186611692316089 0.4723497142246708 1.0 0.8892170810642217 24 P31749,Q9UGN5,P60520,P42574,P14635 5 +Mapk pathway in congenital thyroid cancer 0.6780380239995366 0.7116107146593694 0.4767058702405677 1.0 0.891755776191346 3 P36507 1 +Bladder cancer 0.5309836948558315 0.6794522900157537 0.496851327672793 1.0 0.9052081288886088 6 P42771,P36507 2 +Sarscov2 b117 variant antagonises innate immune activation 0.5454873646209331 0.668527692314062 0.5037968111996798 1.0 0.9130362735300762 2 O94826 1 +Dna repair pathways full network 0.3342687668936479 0.6597213951073602 0.5094326342303113 1.0 0.9182174835822936 42 P18858,P13051,P35244,Q07864 4 +Fbxl10 enhancement of maperk signaling in diffuse large bcell lymphoma 0.5210350300824241 0.6416686528645155 0.5210883467930345 1.0 0.9335510261277024 6 Q9P0M6 1 +Prion disease pathway 0.4865826586559337 0.6356589247472664 0.5249987541341075 1.0 0.9336429255773988 8 P42574 1 +Mirna regulation of p53 pathway in prostate cancer 0.5286387409513782 0.6239045416523155 0.532690277481148 1.0 0.935186328959188 5 Q07812,P42574 2 +Angiogenesis 0.6342375932977052 0.6210785964427263 0.5345479111614464 1.0 0.935186328959188 4 P31749 1 +Oncostatin m signaling pathway 0.3911732214602791 0.6138144737317816 0.5393379317481295 1.0 0.935186328959188 16 P31749,Q16539,P40763,P36507,P42574 5 +Cellular proteostasis 0.6320119295848023 0.6137983194359358 0.5393486079326177 1.0 0.935186328959188 4 Q99471,O15212 2 +Photodynamic therapyinduced nfe2l2 nrf2 survival signaling 0.5250201734355515 0.6107881748968137 0.5413398229189863 1.0 0.9359023760669356 5 O15439 1 +Arrhythmogenic right ventricular cardiomyopathy 0.4242917672924052 0.605800707184075 0.5446471000752975 1.0 0.9378806409150902 12 P35609,P14923 2 +Erbb signaling pathway 0.3940431488558969 0.6029847948790422 0.5465188044293134 1.0 0.9378806409150902 14 P31751,P31749 2 +P38 mapk signaling pathway 0.4650722213152666 0.6019178235522975 0.5472288393872196 1.0 0.9378806409150902 9 P04792,Q9UER7,O43318 3 +G protein signaling pathways 0.385870623243593 0.5729979070723308 0.5666461110726189 1.0 0.9464248578301347 15 P63218,Q08209,P04899 3 +Proteoglycan biosynthesis 0.6355740891621187 0.5718430578059734 0.567428303760988 1.0 0.9464248578301347 3 Q8TB61 1 +Preimplantation embryo 0.4828632150581078 0.558153974303888 0.5767392466283408 1.0 0.948505184180213 7 P17096 1 +Integrated cancer pathway 0.3849887493405191 0.5571564740000252 0.5774205252766558 1.0 0.948505184180213 14 P31749 1 +Glioblastoma signaling pathways 0.370138732322039 0.5384778317535337 0.5902472055978789 1.0 0.9511512120840928 18 Q9NWH9,P31751,P31749 3 +Rac1pak1p38mmp2 pathway 0.366069506378838 0.537002673006047 0.591265767673393 1.0 0.9511512120840928 19 P20936,P40763,P16949,P31749 4 +Dual hijack model of vif in hiv infection 0.6038641672857505 0.5240679399375685 0.6002312863554291 1.0 0.9511512120840928 4 Q13951 1 +Netrinunc5b signaling pathway 0.3756160890799059 0.5211306594268037 0.6022757541919193 1.0 0.9511512120840928 15 P42574,P36507,P31749 3 +Sphingolipid metabolism integrated pathway 0.4879726427301037 0.5204251121095941 0.6027673110753191 1.0 0.9511512120840928 6 Q06136,O95470 2 +Sphingolipid metabolism overview 0.4879726427301037 0.5204251121095941 0.6027673110753191 1.0 0.9511512120840928 6 Q06136,O95470 2 +Copper homeostasis 0.4849237016456648 0.5096331222302568 0.610308514443135 1.0 0.9549154328885991 6 P31749 1 +Small cell lung cancer 0.399635761489568 0.4935381300897182 0.6216324046942177 1.0 0.966447748700307 12 P31751,P31749 2 +Gdnfret signaling axis 0.6052726616106923 0.4783024852844295 0.632434927737735 1.0 0.9709699965289386 3 Q9BW83,Q12948 2 +Parkinubiquitin proteasomal system pathway 0.3220258774527736 0.4774868690290335 0.6330154690317373 1.0 0.9709699965289386 35 P68371,O75832,P55036,O00487,P62333,Q9UNE7 6 +Mapk cascade 0.4754469796737623 0.4765698651240277 0.6336684463013478 1.0 0.9709699965289386 6 Q16539,P36507 2 +Nanoparticlemediated activation of receptor signaling 0.4385297643724922 0.4500760292871143 0.6526556202978033 1.0 0.9787892037683092 8 Q16539,Q9Y490,P36507 3 +Dna damage response 0.341277942227549 0.446159893458852 0.6554817514506484 1.0 0.9787892037683092 21 Q9Y3B8,P14635 2 +Pathways affected in adenoid cystic carcinoma 0.3617724537938666 0.4444999799839307 0.6566811433244586 1.0 0.9787892037683092 14 P46100,P36507,P31749 3 +Melanoma 0.3560504287555532 0.4263226095938239 0.6698727850649457 1.0 0.9794478292343354 15 P31751,P31749 2 +Mitochondrial complex iv assembly 0.3961656847947241 0.4246142571278346 0.6711178980660901 1.0 0.9794478292343354 11 P13073,P09669,Q9Y2R0 3 +Androgen receptor signaling pathway 0.3334560369233723 0.4182981003038536 0.6757291784122395 1.0 0.9794478292343354 25 Q5VUA4,P31749,Q96ST3,Q9UER7,Q9UNE7 5 +Tca cycle in senescence 0.4439083453379898 0.4179917639245441 0.6759531389417932 1.0 0.9794478292343354 7 P17174,P07954,P23368 3 +Serotonin htr1 group and fos pathway 0.4162121857869956 0.4103779790877549 0.6815286974383776 1.0 0.9794478292343354 9 P04899,P36507 2 +Il2 signaling pathway 0.3922353585380895 0.4089066850853158 0.6826081428910538 1.0 0.9794478292343354 11 P36507,P31749 2 +Neuroinflammation 0.5640770134345605 0.4060615613630991 0.6846973680606105 1.0 0.9794478292343354 4 Q16539,P42345 2 +Prolactin signaling pathway 0.3336496560251994 0.4050397232942852 0.6854483121960357 1.0 0.9794478292343354 21 P31749,Q16539,P40763,P36507,P42574 5 +Thymic stromal lymphopoietin tslp signaling pathway 0.3779776035386861 0.4010196612809037 0.6884056484402021 1.0 0.9812853687978929 12 Q16539,P40763,P36507,P31749 4 +Caloric restriction and aging 0.4621370951635418 0.3976519606772458 0.6908867531369101 1.0 0.9812853687978929 5 P31749 1 +Cytoplasmic ribosomal proteins 0.2842315548896091 0.3926726827145589 0.6945612493503439 1.0 0.98299479919989 75 P62906,P47914,P18077,P62249,P62910,Q9Y3U8,P62899,P49406,P62753,P62424,P62841,P32969,P63173,P62263,P62081,P15880,P30050,P62861,P62241,P35268,P62829,P62244,P62269,P39019,P62750,P61247,P08865,P62277,P05388,P46781,P61353,P42766,P18124,P26373,P05387 35 +Mirna regulation of dna damage response 0.3302943467787419 0.3884334379159291 0.6976953031372208 1.0 0.9835755933470076 22 Q9Y3B8,P14635 2 +Oxidative damage response 0.4468759049631561 0.3818220369148704 0.7025933718751496 1.0 0.9835755933470076 6 P42574 1 +Ciliopathies 0.3417588246416686 0.369204174102799 0.7119755448471132 1.0 0.9841526762105784 16 Q13432,Q10713,P57076,Q01968 4 +Mbdnf and probdnf regulation of gaba neurotransmission 0.4385685125450722 0.3558362064711265 0.7219632325606373 1.0 0.9885797979079224 6 O94973 1 +Il3 signaling pathway 0.374434007150783 0.3405742270133351 0.7334241345430164 1.0 0.9885797979079224 11 P31749 1 +Serotonin receptor 467 and nr3c signaling 0.5346849744560362 0.327066846836654 0.7436173264042234 1.0 0.9885797979079224 4 P36507 1 +Serotonin receptor 2 and elksrfgata4 signaling 0.5346849744560362 0.327066846836654 0.7436173264042234 1.0 0.9885797979079224 4 P36507 1 +Glycerolipids and glycerophospholipids 0.5496569158540981 0.324612291931192 0.7454745230183526 1.0 0.9885797979079224 3 O96017,Q9UG56 2 +Cholesterol metabolism with bloch and kandutschrussell pathways 0.3146477992682907 0.3124873860747706 0.7546701479110944 1.0 0.9885797979079224 24 Q16850,Q15392 2 +Modulators of tcr signaling and t cell activation 0.3542118852330588 0.3077859375991575 0.7582452226717022 1.0 0.9885797979079224 12 Q9NQG5,P31749 2 +Wnt signaling 0.3651730726117056 0.3070076847369901 0.7588375229373334 1.0 0.9885797979079224 11 O75116,Q08209,O43318,P56545 4 +Mitochondrial immune response to sarscov2 0.3859246225335135 0.305529883861946 0.7599626133151598 1.0 0.9885797979079224 9 Q9Y276 1 +Hostpathogen interaction of human coronaviruses interferon induction 0.4216956990873164 0.3055031022497578 0.7599830075860607 1.0 0.9885797979079224 6 O43318 1 +Neuroinflammation and glutamatergic signaling 0.319402524262865 0.2898622130232751 0.7719216507604487 1.0 0.9885797979079224 18 P31749,P62136,P17174,P40763,P17612,P34897 6 +Mammary gland development pathway involution stage 4 of 4 0.5348824626933523 0.2884892940035656 0.7729722244770107 1.0 0.9885797979079224 3 P40763 1 +Bmp signaling in eyelid development 0.4393501805054081 0.2845578200255421 0.7759829304549637 1.0 0.9885797979079224 2 Q12948 1 +Eicosanoid synthesis 0.5297941495124643 0.276559274738355 0.7821185393846188 1.0 0.9885797979079224 3 Q9NP80,Q9H7Z7 2 +Mecp2 and associated rett syndrome 0.3150510907002032 0.2711451223470474 0.7862794183540616 1.0 0.9885797979079224 18 Q96ST3,P51608,Q99640,P31749 4 +Pentose phosphate metabolism 0.4180159385548917 0.2705014676033532 0.7867744880105649 1.0 0.9885797979079224 5 P37837 1 +Il4 signaling pathway 0.3645858389258732 0.2694577882630953 0.7875774213382338 1.0 0.9885797979079224 10 P40763,P31749 2 +7q1123 copy number variation syndrome 0.2818769094183598 0.2670843787519711 0.7894041948017974 1.0 0.9885797979079224 41 Q5TC12,P00846 2 +Circadian rhythm genes 0.2802716749295036 0.2629695718798432 0.7925740320425956 1.0 0.9885797979079224 39 Q96ST3,Q03164 2 +Physiological and pathological hypertrophy of the heart 0.393104618535582 0.2599511383763301 0.7949014640671561 1.0 0.9885797979079224 7 Q08209,P40763 2 +Gastrin signaling pathway 0.3029031883780908 0.258107217795612 0.7963241612760339 1.0 0.9885797979079224 25 P42771,P31749,Q16539,Q07157,P40763,P42574,P17612,P62753 8 +Apoptosis 0.3160204051012283 0.2500643832873372 0.8025375591059531 1.0 0.9885797979079224 14 P31749 1 +Supression of hmgb1 mediated inflammation by thbd 0.4263537906137111 0.2481635314295574 0.8040078815937239 1.0 0.9885797979079224 2 P09429 1 +Pyrimidine metabolism 0.2819867286794505 0.2380517808258992 0.8118409330403831 1.0 0.9885797979079224 36 P19388 1 +Leukocyteintrinsic hippo pathway functions 0.3949054138207951 0.233018608917497 0.8157469556459283 1.0 0.9885797979079224 6 Q13043 1 +Endochondral ossification 0.3704570647660549 0.2309644041499328 0.8173424557788969 1.0 0.9885797979079224 8 P31749 1 +Endochondral ossification with skeletal dysplasias 0.3704570647660549 0.2309644041499328 0.8173424557788969 1.0 0.9885797979079224 8 P31749 1 +Ketogenesis and ketolysis 0.3987342099718933 0.2223990604810344 0.8240032431366018 1.0 0.9885797979079224 5 P23786,P35610 2 +Wnt signaling pathway and pluripotency 0.3173443217449855 0.2160008543492392 0.8289870816108804 1.0 0.9885797979079224 13 Q9H0H5,O43318 2 +Pdgf pathway 0.3046908459542864 0.2124201360165885 0.8317792779413895 1.0 0.9885797979079224 15 P53365,P20936 2 +Il10 antiinflammatory signaling pathway 0.3909125891371798 0.2043204298969126 0.8381031059640274 1.0 0.9885797979079224 5 P09601 1 +Tlr4 signaling and tolerance 0.4757118134736808 0.1944222871304318 0.8458452402590875 1.0 0.9885797979079224 4 O43318 1 +Myometrial relaxation and contraction pathways 0.2967918647804939 0.192563465256671 0.8473008598534748 1.0 0.9885797979079224 17 P63218,Q9Y3B8,P17612,Q04917 4 +Tcell receptor tcr signaling pathway 0.2922342221134935 0.1879717850050883 0.8508987692049204 1.0 0.9885797979079224 19 O43318,P31749 2 +Alanine and aspartate metabolism 0.4714595375722652 0.1863390019633632 0.8521789238869417 1.0 0.9885797979079224 4 P17174,P11498,P14868 3 +Apoptosis modulation and signaling 0.296238536006598 0.1832691153442788 0.8545868663355138 1.0 0.9885797979079224 15 Q9Y3E5,P42574 2 +Gaba metabolism aka ghb 0.3978339350180437 0.178515851877176 0.8583178731448031 1.0 0.9902383244647244 2 P51649 1 +Tp53 network 0.4748773472743903 0.1657638885055292 0.8683427656939897 1.0 0.9902447308779536 3 P42771 1 +Sudden infant death syndrome sids susceptibility pathways 0.2809368539522514 0.1611397119698376 0.8719833632920877 1.0 0.9905864644295173 25 P55084,Q04917,Q9H0U9,P42574,P17612,P51608,P10644 7 +Cohesin complex cornelia de lange syndrome 0.2851182399723488 0.1462204438248811 0.8837473671722311 1.0 1.0 14 Q7Z5K2,Q9NTI5 2 +Ketone bodies synthesis and degradation 0.4569470934319683 0.137051959747453 0.8909897246190253 1.0 1.0 3 P35610 1 +Pdgfrbeta pathway 0.328898636504046 0.1323295297681654 0.8947236513763981 1.0 1.0 8 P20936 1 +Pentose phosphate pathway in senescent cells 0.3534535265192923 0.1298858747625716 0.8966567199206406 1.0 1.0 5 P37837 1 +Thyroid hormones production and peripheral downstream signaling effects 0.2780328816661619 0.1260568410107797 0.8996869307552517 1.0 1.0 14 Q16539,Q96B36,P42345,P17612,Q02750,P62753 6 +Focal adhesion 0.2692835546452481 0.1249092103418234 0.9005954266841087 1.0 1.0 30 Q9NWH9,P31749 2 +Mirna regulation of prostate cancer signaling pathways 0.3349542287465459 0.1248843745896928 0.9006150887910154 1.0 1.0 7 Q02750,P36507 2 +H19 action rbe2f1 signaling and cdkbetacatenin activity 0.4467316720837872 0.1223623024331636 0.902612092415562 1.0 1.0 3 P11802,P35222 2 +Nucleotide metabolism 0.2969938428105764 0.1108228425066359 0.9117568312246428 1.0 1.0 11 P30566,P30520,P09884,P23921,P00374,P28340,P13995,P31350,P19623,P22392 10 +Il9 signaling pathway 0.3267741122187808 0.110320590379971 0.9121551281706928 1.0 1.0 7 P36507 1 +15q133 copy number variation syndrome 0.4322860238353151 0.1036293293541434 0.9174635115081098 1.0 1.0 3 P50454,Q16658 2 +Extracellular vesicles in the crosstalk of cardiac cells 0.4088127905236003 0.0917153666451072 0.9269241880345253 1.0 1.0 4 P04792 1 +Type ii diabetes mellitus 0.3440433212996325 0.0866798992024683 0.930925954383622 1.0 1.0 2 P42345 1 +Omega3 omega6 fatty acid synthesis 0.318805464043554 0.0845777831374095 0.9325970622554514 1.0 1.0 6 O15254,Q15067 2 +Parkinsons disease pathway 0.2985772965863625 0.0796569663022553 0.9365100865572512 1.0 1.0 8 P42574 1 +Exerciseinduced circadian regulation 0.2590203908211695 0.0789933056916582 0.9370379477099262 1.0 1.0 14 Q96PU8 1 +Fgfr3 signaling in chondrocyte proliferation and terminal differentiation 0.3052253248052898 0.0772519389826586 0.9384231237268146 1.0 1.0 7 Q16539,P36507 2 +Vitamin d receptor pathway 0.2713970275013249 0.0739612085468107 0.941041251779872 1.0 1.0 12 Q92783 1 +Hif1a and pparg regulation of glycolysis 0.3918382087396117 0.0632536279460787 0.9495645413127536 1.0 1.0 3 P04406,P00338 2 +Cori cycle 0.2712785222745388 0.0628293846960635 0.9499023664842996 1.0 1.0 11 P00558,P37837,P18669,P06744,P00338,P60174,P19367,Q01813,P04406,P04075 10 +Glycolysis in senescence 0.2708182476466372 0.0543145718588281 0.9566845400263332 1.0 1.0 10 P04637,P11413,P00558,P06733,P00338,P14618,Q13131,P19367,P04406 9 +Urea cycle and metabolism of amino groups 0.2846889612265398 0.052617473030837 0.958036694790158 1.0 1.0 7 P32322 1 +Valproic acid pathway 0.285610990600138 0.0472104370618078 0.9623455092262948 1.0 1.0 6 P55084,P26440,Q13547,Q99714,P45954 5 +Gastric cancer network 1 0.275412810217439 0.0435482678166104 0.9652644888423908 1.0 1.0 7 P62805 1 +Osteopontin signaling 0.3442919075144529 0.0389037017392977 0.9689671652437876 1.0 1.0 4 Q02750,P27361,O15111 3 +Endoplasmic reticulum stress response in coronavirus infection 0.2645464401879285 0.0323590874657961 0.9741856888608584 1.0 1.0 5 Q96QC0,P19525,P05198,P62136 4 +Thiamine metabolic pathways 0.3200867052023131 0.0283522529613502 0.9773812054926808 1.0 1.0 4 P29401,Q02218,Q9HC21 3 +Nipbl role in dna damage cornelia de lange syndrome 0.3236191658567053 0.0282831538429201 0.9774363165114486 1.0 1.0 3 P16104 1 +Unfolded protein response 0.2966040462427769 0.0215949321762697 0.9827710761279154 1.0 1.0 4 P04637,Q9Y3I0,P42575 3 +Tryptophan metabolism 0.224475099709203 0.0175086043102765 0.9860308686523244 1.0 1.0 15 Q15392 1 +Metabolic reprogramming in colon cancer 0.2321392315090319 0.0096907673454393 0.9922680073727544 1.0 1.0 35 P11177,Q06203,Q9Y617,P07954,P32322,P37837,P06733,P29401,P06744,Q96I99,Q15758,P14618,P04406,P34897 14 diff --git a/msigdb_wp/selections.json b/msigdb_wp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..f03b4dc2d5c70c3a3a2f736b1b4adcb635c60382 --- /dev/null +++ b/msigdb_wp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["15q112 copy number variation syndrome", "15q133 copy number variation syndrome", "16p112 distal deletion syndrome", "16p112 proximal deletion syndrome", "1q211 copy number variation syndrome", "22q112 copy number variation syndrome", "3q29 copy number variation syndrome", "4hydroxytamoxifen dexamethasone and retinoic acids regulation of p27 expression", "7oxoc and 7betahc pathways", "7q1123 copy number variation syndrome", "Acetylcholine synthesis", "Acquired partial lipodystrophy barraquersimons syndrome", "Acute viral myocarditis", "Adipogenesis", "Aerobic glycolysis", "Aflatoxin b1 metabolism", "Agerage pathway", "Airway smooth muscle cell contraction", "Alanine and aspartate metabolism", "Allograft rejection", "Alpha 6 beta 4 signaling pathway", "Altered glycosylation of muc1 in tumor microenvironment", "Alternative pathway of fetal androgen synthesis", "Alzheimers disease", "Alzheimers disease and mirna effects", "Amino acid metabolism", "Amino acid metabolism pathway excerpt histidine catabolism extension", "Ampactivated protein kinase ampk signaling", "Amyotrophic lateral sclerosis als", "Androgen receptor signaling pathway", "Angiogenesis", "Angiopoietinlike protein 8 regulatory pathway", "Angiotensin ii receptor type 1 pathway", "Antiviral and antiinflammatory effects of nrf2 on sarscov2 pathway", "Apoptosis", "Apoptosis modulation and signaling", "Apoptosis modulation by hsp70", "Apoptosisrelated network due to altered notch3 in ovarian cancer", "Arachidonate epoxygenase epoxide hydrolase", "Arrhythmogenic right ventricular cardiomyopathy", "Aryl hydrocarbon receptor pathway wp2586", "Aryl hydrocarbon receptor pathway wp2873", "Aspirin and mirnas", "Atm signaling in development and disease", "Atm signaling pathway", "Atr signaling", "Autophagy", "Autosomal recessive osteopetrosis pathways", "B cell receptor signaling pathway", "Base excision repair", "Bdnftrkb signaling", "Benzene metabolism", "Benzoapyrene metabolism", "Bile acids synthesis and enterohepatic circulation", "Biogenic amine synthesis", "Biomarkers for pyrimidine metabolism disorders", "Biomarkers for urea cycle disorders", "Biotin metabolism including iems", "Bladder cancer", "Bmp signaling in eyelid development", "Bmp2wnt4foxo1 pathway in primary endometrial stromal cell differentiation", "Brainderived neurotrophic factor bdnf signaling pathway", "Breast cancer pathway", "Burn wound healing", "Calcium regulation in cardiac cells", "Caloric restriction and aging", "Camkk2 pathway", "Cancer immunotherapy by ctla4 blockade", "Cancer immunotherapy by pd1 blockade", "Cannabinoid receptor signaling", "Canonical and noncanonical notch signaling", "Canonical and noncanonical tgfb signaling", "Canonical nfkb pathway", "Cardiac hypertrophic response", "Cardiac progenitor differentiation", "Ccl18 signaling pathway", "Cell cycle", "Cell differentiation expanded index", "Cell differentiation index", "Cell migration and invasion through p75ntr", "Cells and molecules involved in local acute inflammatory response", "Celltype dependent selectivity of cck2r signaling", "Cellular proteostasis", "Cerebral organic acidurias including diseases", "Chemokine signaling pathway", "Cholesterol biosynthesis pathway", "Cholesterol biosynthesis with skeletal dysplasias", "Cholesterol metabolism with bloch and kandutschrussell pathways", "Chromosomal and microsatellite instability in colorectal cancer", "Ciliary landscape", "Ciliopathies", "Circadian rhythm genes", "Classical pathway of steroidogenesis with glucocorticoid and mineralocorticoid metabolism", "Clear cell renal cell carcinoma pathways", "Codeine and morphine metabolism", "Cohesin complex cornelia de lange syndrome", "Common pathways underlying drug addiction", "Complement and coagulation cascades", "Complement system", "Complement system in neuronal development and plasticity", "Congenital generalized lipodystrophy cgl", "Constitutive androstane receptor pathway", "Control of immune tolerance by vasoactive intestinal peptide", "Copper homeostasis", "Cori cycle", "Corticotropinreleasing hormone signaling pathway", "Cysteine and methionine catabolism", "Cytoplasmic ribosomal proteins", "Cytosine methylation", "Cytosolic dnasensing pathway", "Ddx1 as a regulatory component of the drosha microprocessor", "Degradation pathway of sphingolipids including diseases", "Deregulation of rab and rab effector genes in bladder cancer", "Development of pulmonary dendritic cells and macrophage subsets", "Development of ureteric collection system", "Disorders of folate metabolism and transport", "Disruption of postsynaptic signaling by cnv", "Dna damage response", "Dna damage response only atm dependent", "Dna irdamage and cellular response via atr", "Dna irdouble strand breaks and cellular response via atm", "Dna mismatch repair", "Dna repair pathways full network", "Dna replication", "Dopamine metabolism", "Dopaminergic neurogenesis", "Drug induction of bile acid pathway", "Dual hijack model of vif in hiv infection", "Ebola virus infection in host", "Ebsteinbarr virus lmp1 signaling", "Ectoderm differentiation", "Effect of progerin on genes involved in hutchinsongilford progeria syndrome", "Egfegfr signaling pathway", "Egfr tyrosine kinase inhibitor resistance", "Eicosanoid metabolism via cyclooxygenases cox", "Eicosanoid metabolism via cytochrome p450 monooxygenases pathway", "Eicosanoid metabolism via lipooxygenases lox", "Eicosanoid synthesis", "Electron transport chain oxphos system in mitochondria", "Embryonic stem cell pluripotency pathways", "Endochondral ossification", "Endochondral ossification with skeletal dysplasias", "Endoderm differentiation", "Endometrial cancer", "Endoplasmic reticulum stress response in coronavirus infection", "Endothelin pathways", "Energy metabolism", "Envelope proteins and their potential roles in edmd physiopathology", "Epithelial to mesenchymal transition in colorectal cancer", "Epo receptor signaling", "Erbb signaling pathway", "Erk pathway in huntingtons disease", "Estrogen metabolism", "Estrogen receptor pathway", "Estrogen signaling pathway", "Ethanol effects on histone modifications", "Ethanol metabolism production of ros by cyp2e1", "Eukaryotic transcription initiation", "Exerciseinduced circadian regulation", "Exrna mechanism of action and biogenesis", "Extracellular vesiclemediated signaling in recipient cells", "Extracellular vesicles in the crosstalk of cardiac cells", "Factors and pathways affecting insulinlike growth factor igf1akt signaling", "Familial hyperlipidemia type 1", "Familial hyperlipidemia type 2", "Familial hyperlipidemia type 3", "Familial hyperlipidemia type 4", "Familial hyperlipidemia type 5", "Familial partial lipodystrophy fpld", "Farnesoid x receptor pathway", "Fas ligand pathway and stress induction of heat shock proteins", "Fatty acid betaoxidation", "Fatty acid biosynthesis", "Fatty acid omegaoxidation", "Fatty acid transporters", "Fbxl10 enhancement of maperk signaling in diffuse large bcell lymphoma", "Ferroptosis", "Fgfr3 signaling in chondrocyte proliferation and terminal differentiation", "Fibrin complement receptor 3 signaling pathway", "Fluoroacetic acid toxicity", "Fluoropyrimidine activity", "Focal adhesion", "Focal adhesion pi3kaktmtorsignaling pathway", "Folate metabolism", "Folatealcohol and cancer pathway hypotheses", "Follicle stimulating hormone fsh signaling pathway", "Foxa2 pathway", "Foxp3 in covid19", "Fragile x syndrome", "Fto obesity variant mechanism", "G protein signaling pathways", "G1 to s cell cycle control", "G13 signaling pathway", "Gaba metabolism aka ghb", "Gaba receptor signaling", "Gammaglutamyl cycle for the biosynthesis and degradation of glutathione including diseases", "Gastric cancer network 1", "Gastric cancer network 2", "Gastrin signaling pathway", "Gdnfret signaling axis", "Genes controlling nephrogenesis", "Genes related to primary cilium development based on crispr", "Glial cell differentiation", "Glioblastoma signaling pathways", "Glucocorticoid receptor pathway", "Glucuronidation", "Glutathione metabolism", "Glycerolipids and glycerophospholipids", "Glycerophospholipid biosynthetic pathway", "Glycogen synthesis and degradation", "Glycolysis and gluconeogenesis", "Glycolysis in senescence", "Glycosaminoglycan degradation", "Glycosylation and related congenital defects", "Gpcrs class a rhodopsinlike", "Gpr143 in melanocytes and retinal pigment epithelium cells", "Gpr40 pathway", "H19 action rbe2f1 signaling and cdkbetacatenin activity", "Hair follicle development cytodifferentiation part 3 of 3", "Hair follicle development organogenesis part 2 of 3", "Head and neck squamous cell carcinoma", "Heart development", "Hedgehog signaling pathway wp4249", "Hedgehog signaling pathway wp47", "Hematopoietic stem cell gene regulation by gabp alphabeta complex", "Heme biosynthesis", "Hepatitis b infection", "Hepatitis c and hepatocellular carcinoma", "Hepatocyte growth factor receptor signaling", "Hereditary leiomyomatosis and renal cell carcinoma pathway", "Hif1a and pparg regulation of glycolysis", "Hijack of ubiquitination by sarscov2", "Hippo signaling regulation pathways", "Hippomerlin signaling dysregulation", "Hippoyap signaling pathway", "Histone modifications", "Homologous recombination", "Hostpathogen interaction of human coronaviruses apoptosis", "Hostpathogen interaction of human coronaviruses autophagy", "Hostpathogen interaction of human coronaviruses interferon induction", "Hostpathogen interaction of human coronaviruses mapk signaling", "Hypertrophy model", "Hypothesized pathways in pathogenesis of cardiovascular disease", "Hypothetical craniofacial development pathway", "Id signaling pathway", "Il1 signaling pathway", "Il10 antiinflammatory signaling pathway", "Il17 signaling pathway", "Il18 signaling pathway", "Il2 signaling pathway", "Il3 signaling pathway", "Il4 signaling pathway", "Il5 signaling pathway", "Il6 signaling pathway", "Il7 signaling pathway", "Il9 signaling pathway", "Imatinib and chronic myeloid leukemia", "Immune response to tuberculosis", "Inclusion body myositis", "Influence of laminopathies on wnt signaling", "Inhibition of exosome biogenesis and secretion by manumycin a in crpc cells", "Initiation of transcription and translation elongation at the hiv1 ltr", "Insulin signaling", "Insulin signaling in adipocytes diabetic condition", "Insulin signaling in adipocytes normal condition", "Integrated cancer pathway", "Integrinmediated cell adhesion", "Interactions between immune cells and micrornas in tumor microenvironment", "Interactions between loxl4 and oxidative stress pathway", "Interactome of polycomb repressive complex 2 prc2", "Interferon type i signaling pathways", "Interleukin1 il1 structural pathway", "Interleukin1 induced activation of nfkb", "Interleukin11 signaling pathway", "Intracellular trafficking proteins involved in cmt neuropathy", "Intraflagellar transport proteins binding to dynein", "Irinotecan pathway", "Iron metabolism in placenta", "Joubert syndrome", "Kallmann syndrome", "Kennedy pathway from sphingolipids", "Ketogenesis and ketolysis", "Ketone bodies synthesis and degradation", "Kininkallikrein pathway", "Kisspeptinkisspeptin receptor system in the ovary", "Kit receptor signaling pathway", "Krebs cycle disorders", "Kynurenine pathway and links to cell senescence", "Ldlrad4 and what we know about it", "Leptin and adiponectin", "Leptin signaling pathway", "Leptininsulin signaling overlap", "Leukocyteintrinsic hippo pathway functions", "Linoleic acid metabolism affected by coronavirus infection", "Lipid metabolism pathway", "Liver x receptor pathway", "Lncrna in canonical wnt signaling and colorectal cancer", "Lncrnamediated mechanisms of therapeutic resistance", "Ltf danger signal response pathway", "Lung fibrosis", "Male infertility", "Malignant pleural mesothelioma", "Mammalian disorder of sexual development", "Mammary gland development pathway embryonic development stage 1 of 4", "Mammary gland development pathway involution stage 4 of 4", "Mammary gland development pathway pregnancy and lactation stage 3 of 4", "Mammary gland development pathway puberty stage 2 of 4", "Map3k1 role in promoting and blocking gonadal determination", "Mapk and nfkb signaling pathways inhibited by yersinia yopj", "Mapk cascade", "Mapk pathway in congenital thyroid cancer", "Mapk signaling pathway", "Matrix metalloproteinases", "Mbdnf and probdnf regulation of gaba neurotransmission", "Measles virus infection", "Mechanoregulation and pathology of yaptaz via hippo and nonhippo mechanisms", "Mecp2 and associated rett syndrome", "Melanoma", "Melatonin metabolism and effects", "Mesodermal commitment pathway", "Met in type 1 papillary renal cell carcinoma", "Metabolic pathway of ldl hdl and tg including diseases", "Metabolic reprogramming in colon cancer", "Metabolism of alphalinolenic acid", "Metabolism of spingolipids in er and golgi apparatus", "Metapathway biotransformation phase i and ii", "Metastatic brain tumor", "Methionine de novo and salvage pathway", "Methionine metabolism leading to sulfur amino acids and related disorders", "Methylation pathways", "Mevalonate arm of cholesterol biosynthesis pathway", "Mevalonate pathway", "Mfap5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement", "Mfap5mediated ovarian cancer cell motility and invasiveness", "Microglia pathogen phagocytosis pathway", "Microrna network associated with chronic lymphocytic leukemia", "Micrornas in cardiomyocyte hypertrophy", "Microtubule cytoskeleton regulation", "Mir124 predicted interactions with cell cycle and differentiation", "Mir517 relationship with arcn1 and usp1", "Mirna biogenesis", "Mirna regulation of dna damage response", "Mirna regulation of p53 pathway in prostate cancer", "Mirna regulation of prostate cancer signaling pathways", "Mirnas involved in dna damage response", "Mirnas involvement in the immune response in sepsis", "Mitochondrial complex i assembly model oxphos system", "Mitochondrial complex ii assembly", "Mitochondrial complex iii assembly", "Mitochondrial complex iv assembly", "Mitochondrial fatty acid synthesis pathway", "Mitochondrial gene expression", "Mitochondrial immune response to sarscov2", "Mitochondrial long chain fatty acid betaoxidation", "Modulators of tcr signaling and t cell activation", "Monoamine transport", "Mrna processing", "Mrna protein and metabolite inducation pathway by cyclosporin a", "Mthfr deficiency", "Myd88 distinct inputoutput pathway", "Myometrial relaxation and contraction pathways", "Nad biosynthetic pathways", "Nad metabolism", "Nad metabolism in oncogeneinduced senescence and mitochondrial dysfunctionassociated senescence", "Nad metabolism sirtuins and aging", "Nanomaterial induced apoptosis", "Nanomaterialinduced inflammasome activation", "Nanoparticle triggered autophagic cell death", "Nanoparticle triggered regulated necrosis", "Nanoparticlemediated activation of receptor signaling", "Ncrnas involved in stat3 signaling in hepatocellular carcinoma", "Ncrnas involved in wnt signaling in hepatocellular carcinoma", "Neovascularisation processes", "Nephrogenesis", "Nephrotic syndrome", "Netrinunc5b signaling pathway", "Network map of sarscov2 signaling pathway", "Neural crest cell migration during development", "Neural crest cell migration in cancer", "Neural crest differentiation", "Neurodegeneration with brain iron accumulation nbia subtypes pathway", "Neuroinflammation", "Neuroinflammation and glutamatergic signaling", "Nicotine effect on dopaminergic neurons", "Nipbl role in dna damage cornelia de lange syndrome", "Nitric oxide metabolism in cystic fibrosis", "Nocgmppkg mediated neuroprotection", "Nodlike receptor nlr signaling pathway", "Nonalcoholic fatty liver disease", "Nongenomic actions of 125 dihydroxyvitamin d3", "Nonhomologous end joining", "Nonsmall cell lung cancer", "Notch signaling", "Notch signaling pathway", "Notch1 regulation of endothelial cell calcification", "Novel intracellular components of rigilike receptor rlr pathway", "Nrf2 pathway", "Nrf2are regulation", "Nrp1triggered signaling pathways in pancreatic cancer", "Nsp1 from sarscov2 inhibits translation initiation in the host cell", "Nuclear receptors in lipid metabolism and toxicity", "Nuclear receptors metapathway", "Nucleotide excision repair", "Nucleotide excision repair in xeroderma pigmentosum", "Nucleotide metabolism", "Nucleotidebinding oligomerization domain nod pathway", "Oligodendrocyte specification and differentiation leading to myelin components for cns", "Omega3 omega6 fatty acid synthesis", "Omega9 fatty acid synthesis", "Oncostatin m signaling pathway", "Onecarbon metabolism", "Onecarbon metabolism and related pathways", "Orexin receptor pathway", "Osteoblast differentiation and related diseases", "Osteoclast signaling", "Osteopontin signaling", "Osx and mirnas in tooth development", "Ovarian infertility", "Overlap between signal transduction pathways contributing to lmna laminopathies", "Overview of interferonsmediated signaling pathway", "Overview of nanoparticle effects", "Oxidation by cytochrome p450", "Oxidative damage response", "Oxidative phosphorylation", "Oxidative stress response", "Oxysterols derived from cholesterol", "P38 mapk signaling pathway", "P53 transcriptional gene network", "Pancreatic adenocarcinoma pathway", "Parkinsons disease pathway", "Parkinubiquitin proteasomal system pathway", "Pathogenesis of sarscov2 mediated by nsp9nsp10 complex", "Pathogenic escherichia coli infection", "Pathways affected in adenoid cystic carcinoma", "Pathways of nucleic acid metabolism and innate immune sensing", "Pdgf pathway", "Pdgfrbeta pathway", "Pentose phosphate metabolism", "Pentose phosphate pathway in senescent cells", "Peroxiredoxin 2 induced ovarian failure", "Phase i biotransformations non p450", "Phosphodiesterases in neuronal function", "Phosphoinositides metabolism", "Photodynamic therapyinduced ap1 survival signaling", "Photodynamic therapyinduced hif1 survival signaling", "Photodynamic therapyinduced nfe2l2 nrf2 survival signaling", "Photodynamic therapyinduced nfkb survival signaling", "Photodynamic therapyinduced unfolded protein response", "Physicochemical features and toxicityassociated pathways", "Physiological and pathological hypertrophy of the heart", "Pi3kakt signaling pathway", "Pi3kaktmtor signaling pathway and therapeutic opportunities", "Pi3kaktmtor vitd3 signaling", "Pilocytic astrocytoma", "Ppar signaling pathway", "Pparalpha pathway", "Praderwilli and angelman syndrome", "Pregnane x receptor pathway", "Preimplantation embryo", "Primary focal segmental glomerulosclerosis fsgs", "Prion disease pathway", "Progeriaassociated lipodystrophy", "Prolactin signaling pathway", "Prostaglandin and leukotriene metabolism in senescence", "Prostaglandin synthesis and regulation", "Proteasome degradation", "Proteoglycan biosynthesis", "Proximal tubule transport", "Ptf1a related regulatory pathway", "Purine metabolism", "Purine metabolism and related disorders", "Purinergic signaling", "Pyrimidine metabolism", "Pyrimidine metabolism and related diseases", "Rac1pak1p38mmp2 pathway", "Rala downstream regulated genes", "Ranklrank signaling pathway", "Ras and bradykinin pathways in covid19", "Ras signaling", "Regucalcin in proximal tubule epithelial kidney cells", "Regulation of actin cytoskeleton", "Regulation of apoptosis by parathyroid hormonerelated protein", "Regulation of sister chromatid separation at the metaphaseanaphase transition", "Regulation of wnt bcatenin signaling by small molecule compounds", "Regulatory circuits of the stat3 signaling pathway", "Relationship between inflammation cox2 and egfr", "Resistin as a regulator of inflammation", "Retinoblastoma gene in cancer", "Rett syndrome causing genes", "Riboflavin and coq disorders", "Robo4 and vegf signaling pathways crosstalk", "S1p receptor signal transduction", "Sars coronavirus and innate immunity", "Sarscov2 and covid19 pathway", "Sarscov2 b117 variant antagonises innate immune activation", "Sarscov2 innate immunity evasion and cellspecific immune response", "Selenium micronutrient network", "Serine metabolism", "Serotonin and anxiety", "Serotonin and anxietyrelated events", "Serotonin htr1 group and fos pathway", "Serotonin receptor 2 and elksrfgata4 signaling", "Serotonin receptor 467 and nr3c signaling", "Serotonin transporter activity", "Signal transduction through il1r", "Sleep regulation", "Small cell lung cancer", "Smc1smc3 role in dna damage cornelia de lange syndrome", "Somatroph axis gh and its relationship to dietary restriction and aging", "Sphingolipid metabolism in senescence", "Sphingolipid metabolism integrated pathway", "Sphingolipid metabolism overview", "Sphingolipid pathway", "Spinal cord injury", "Splicing factor nova regulated synaptic proteins", "Srebf and mir33 in cholesterol and lipid homeostasis", "Statin inhibition of cholesterol production", "Steroid biosynthesis", "Sterol regulatory elementbinding proteins srebp signaling", "Sting pathway in kawasakilike disease and covid19", "Striated muscle contraction pathway", "Sudden infant death syndrome sids susceptibility pathways", "Sulfation biotransformation reaction", "Supression of hmgb1 mediated inflammation by thbd", "Synaptic signaling pathways associated with autism spectrum disorder", "Synaptic vesicle pathway", "T cell receptor and costimulatory signaling", "Tamoxifen metabolism", "Target of rapamycin tor signaling", "Tca cycle aka krebs or citric acid cycle", "Tca cycle and deficiency of pyruvate dehydrogenase complex pdhc", "Tca cycle in senescence", "Tca cycle nutrient use and invasiveness of ovarian cancer", "Tcell activation sarscov2", "Tcell antigen receptor tcr pathway during staphylococcus aureus infection", "Tcell receptor tcr signaling pathway", "Tgfbeta receptor signaling", "Tgfbeta receptor signaling in skeletal dysplasias", "Tgfbeta signaling in thyroid cells for epithelialmesenchymal transition", "Tgfbeta signaling pathway", "Thermogenesis", "Thiamine metabolic pathways", "Thymic stromal lymphopoietin tslp signaling pathway", "Thyroid hormones production and peripheral downstream signaling effects", "Thyroid stimulating hormone tsh signaling pathway", "Tlr4 signaling and tolerance", "Tnfalpha signaling pathway", "Tnfrelated weak inducer of apoptosis tweak signaling pathway", "Tolllike receptor signaling pathway", "Tolllike receptor signaling related to myd88", "Tp53 network", "Transcription cofactors ski and skil protein partners", "Transcription factor regulation in adipogenesis", "Transcription factors regulate mirnas related to cardiac hypertrophy", "Transcriptional activation by nrf2 in response to phytochemicals", "Translation factors", "Translation inhibitors in chronically activated pdgfra cells", "Transsulfuration and onecarbon metabolism", "Transsulfuration pathway", "Triacylglyceride synthesis", "Tryptophan catabolism leading to nad production", "Tryptophan metabolism", "Tumor suppressor activity of smarcb1", "Type 2 papillary renal cell carcinoma", "Type i collagen synthesis in the context of osteogenesis imperfecta", "Type i interferon induction and signaling during sarscov2 infection", "Type ii diabetes mellitus", "Type ii interferon signaling ifng", "Type iii interferon signaling", "Tyrobp causal network in microglia", "Ultraconserved region 339 modulation of tumor suppressor micrornas in cancer", "Unfolded protein response", "Urea cycle and associated pathways", "Urea cycle and metabolism of amino groups", "Urea cycle and related diseases", "Valproic acid pathway", "Vasopressinregulated water reabsorption", "Vegfavegfr2 signaling pathway", "Vitamin a and carotenoid metabolism", "Vitamin b12 disorders", "Vitamin b12 metabolism", "Vitamin b6dependent and responsive disorders", "Vitamin d in inflammatory diseases", "Vitamin d metabolism", "Vitamin d receptor pathway", "Vitamin dsensitive calcium signaling in depression", "White fat cell differentiation", "Wnt signaling", "Wnt signaling in kidney disease", "Wnt signaling pathway", "Wnt signaling pathway and pluripotency", "Wntbetacatenin signaling pathway in leukemia", "Zinc homeostasis"], "available_proteins": ["AAMP", "AAR2", "AARS", "AASS", "ABCB1", "ABCC1", "ABCC4", "ABCD3", "ABCF1", "ABCF2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACLY", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR2", "ACTR3", "ADA", "ADAR", "ADH5", "ADI1", "ADK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGL", "AGPAT1", "AGPS", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK4", "AKAP1", "AKAP12", "AKAP8", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT1S1", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "AMOT", "ANAPC5", "ANAPC7", "ANK3", "ANLN", "ANP32A", "ANXA1", "ANXA2", "ANXA4", "ANXA6", "AP1G1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "APEX1", "APMAP", "APRT", "ARCN1", "ARF4", "ARFGAP1", "ARFGAP2", "ARFIP2", "ARHGAP5", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARL2", "ARL3", "ARL8B", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ASAH1", "ASCC3", "ASNA1", "ASNS", "ATG3", "ATIC", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0D1", "ATP6V1A", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7B", "ATPAF1", "ATPIF1", "ATRX", "ATXN10", "ATXN2L", "BAG2", "BAG3", "BAG4", "BAIAP2", "BAK1", "BANF1", "BAX", "BAZ1A", "BAZ1B", "BCAT2", "BCL10", "BCL2L12", "BCL2L13", "BCLAF1", "BCS1L", "BLVRA", "BLVRB", "BRIX1", "BSG", "BTF3", "BUB3", "C15orf39", "C1QBP", "C21orf59", "CAB39", "CACYBP", "CAD", "CALD1", "CALR", "CALU", "CAND1", "CAP1", "CAPN1", "CAPZB", "CARM1", "CASK", "CASP2", "CASP3", "CASP6", "CBFB", "CBR1", "CBX1", "CBX3", "CBX5", "CCAR2", "CCDC124", "CCDC6", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD47", "CD81", "CDC23", "CDC27", "CDC37", "CDC42", "CDC45", "CDC73", "CDK1", "CDK2", "CDK4", "CDK6", "CDKAL1", "CDKN2A", "CDS2", "CEBPZ", "CELF1", "CELF2", "CEP170", "CEP44", "CERS2", "CFL1", "CFL2", "CHAF1A", "CHAMP1", "CHD1", "CHD1L", "CHD4", "CHEK2", "CHKA", "CHMP5", "CHORDC1", "CHRAC1", "CHST14", "CHUK", "CIP2A", "CKB", "CLASP2", "CLCN7", "CLIC1", "CLP1", "CLPTM1L", "CLSPN", "CLTA", "CLTC", "CLUH", "CMPK1", "CNN2", "CNOT1", "CNOT9", "CNP", "COA3", "COASY", "COL4A3BP", "COLGALT1", "COMT", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7C", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPT2", "CRK", "CRKL", "CRTAP", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CXADR", "CYB5B", "CYB5R3", "CYC1", "CYFIP1", "CYP20A1", "CYP51A1", "DARS", "DAXX", "DBNL", "DCAF7", "DCTN1", "DCTN2", "DCTN4", "DCTPP1", "DDB1", "DDOST", "DDX1", "DDX17", "DDX20", "DDX21", "DDX3X", "DDX5", "DDX52", "DDX56", "DEK", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHFR", "DHX15", "DHX16", "DHX29", "DHX36", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DLAT", "DLD", "DLST", "DNAAF5", "DNAJA1", "DNAJB1", "DNAJB11", "DNAJC3", "DNAJC7", "DNAJC8", "DNM1", "DNM1L", "DNM2", "DNMT1", "DPF2", "DPM1", "DPP9", "DPYSL2", "DSG2", "DSP", "DSTN", "DTYMK", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "EBP", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECSIT", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFTUD2", "EHD1", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF4A1", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAVL1", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP3", "ELP4", "EMD", "EML4", "ENO1", "ENOPH1", "EPB41", "EPB41L2", "EPB41L3", "EPHX1", "EPHX2", "EPRS", "ERCC2", "ERI1", "ESD", "ESS2", "ETF1", "ETFA", "ETFDH", "EWSR1", "EXO1", "EXOC2", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOSC2", "EXOSC4", "EXOSC7", "EXOSC9", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAH", "FAM120A", "FAM91A1", "FANCD2", "FANCI", "FARSB", "FASN", "FAU", "FDFT1", "FDPS", "FECH", "FEN1", "FGFR1OP", "FH", "FHL1", "FHOD1", "FKBP10", "FKBP1A", "FKBP2", "FKBP4", "FKBP5", "FLCN", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNTA", "FOXC1", "FOXRED1", "FSCN1", "FTO", "FUS", "FXR1", "FXR2", "G3BP1", "G6PD", "GABARAPL2", "GALNT1", "GAPDH", "GART", "GBA", "GCC2", "GCDH", "GCLM", "GDI1", "GFPT1", "GGCT", "GGCX", "GGH", "GIGYF2", "GLA", "GLB1", "GLS", "GLUD1", "GM2A", "GMPPB", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG12", "GNG5", "GNS", "GOT1", "GOT2", "GPD2", "GPI", "GPS1", "GPT2", "GRB2", "GRSF1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2E1", "GTF2I", "GTPBP4", "GUSB", "GYG1", "GYS1", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HADH", "HADHA", "HADHB", "HAT1", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HEBP1", "HELLS", "HERC2", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGCL", "HMGCS1", "HMGN1", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HPRT1", "HSD17B10", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HYOU1", "IARS", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP3", "ILF2", "IMP3", "IMPAD1", "IMPDH2", "INF2", "IPO9", "IQGAP1", "IRF2BPL", "IRS4", "ITCH", "ITGB1", "ITPA", "IVD", "JUP", "KAT7", "KDM1A", "KDM1B", "KDM3B", "KDSR", "KHDRBS1", "KHSRP", "KIF22", "KIF23", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KLC1", "KLC2", "KLC4", "KMT2A", "KPNA1", "KPNB1", "KTN1", "L2HGDH", "LARP1", "LARP7", "LARS2", "LBR", "LDHA", "LDHB", "LEMD3", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMNA", "LMNB1", "LMNB2", "LPGAT1", "LRPPRC", "LRRC59", "LRWD1", "LSM2", "LSS", "LTA4H", "LZTFL1", "MACF1", "MANF", "MAP1B", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCKS", "MARK2", "MARS", "MAT2A", "MAT2B", "MAU2", "MAVS", "MCAT", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDC1", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MEPCE", "MFN2", "MGST2", "MGST3", "MIA3", "MIF", "MKI67", "MMAB", "MOGS", "MORF4L1", "MOV10", "MPG", "MPI", "MPP2", "MPST", "MRE11", "MRI1", "MRPL19", "MRPL40", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTDH", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR6", "MTOR", "MUT", "MVD", "MVK", "MYBBP1A", "MYEF2", "MYH10", "MYH9", "MYL6", "MYO1C", "MYO6", "NAA15", "NAA40", "NAA50", "NAE1", "NAGLU", "NAMPT", "NAP1L1", "NAPA", "NARS", "NAT10", "NBN", "NCAPG", "NCAPH2", "NCBP1", "NCDN", "NCK1", "NCKAP1", "NCL", "NCSTN", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NEDD4", "NEFL", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NIPA2", "NKRF", "NLRX1", "NME1", "NME2", "NONO", "NOP2", "NPC1", "NSDHL", "NSF", "NT5C3A", "NUBPL", "NUDC", "NUDT21", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP214", "NUP62", "NUP88", "NUP98", "NXF1", "OAT", "OCRL", "OGDH", "OGT", "OPA1", "ORC3", "OXSR1", "P3H1", "P4HA1", "P4HB", "PABPC1", "PABPN1", "PAF1", "PAFAH1B1", "PAICS", "PAIP1", "PAK2", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PBK", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCM1", "PCNA", "PDCD4", "PDCD6", "PDCD6IP", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA6", "PDLIM5", "PDS5A", "PDS5B", "PEBP1", "PECR", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGRMC2", "PHB", "PHB2", "PHF5A", "PHF6", "PHGDH", "PI4K2A", "PIK3C2A", "PIN1", "PISD", "PKM", "PKMYT1", "PKN2", "PLCG1", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PMPCA", "PMVK", "PNP", "PNPLA8", "PNPO", "PNPT1", "POLA1", "POLA2", "POLD1", "POLDIP2", "POLE", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLRMT", "PON2", "POR", "PPAT", "PPIB", "PPID", "PPIF", "PPM1G", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R1", "PPP5C", "PPT2", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PRIM1", "PRIM2", "PRKAA1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF3", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRRC2C", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSPC1", "PTBP1", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPA", "PTPN1", "PTPN11", "PTRH2", "PURA", "PUS1", "PXN", "PYCR1", "PYCR2", "PYGB", "PYGL", "QKI", "RAB10", "RAB13", "RAB14", "RAB21", "RAB3B", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB8B", "RABGAP1", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAN", "RANBP1", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RASA1", "RBM14", "RBM17", "RBM39", "RBM4", "RBMX", "RBP1", "RCC1", "RCN1", "RDH14", "RDX", "RECQL", "RETSAT", "REXO2", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHOA", "RHOG", "RIF1", "RNASEH2A", "RNASEH2B", "RNASET2", "RNF14", "RNF40", "RNMT", "RNPS1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPRD1B", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RRM1", "RRM2", "RTCB", "RTN3", "RTN4", "RUVBL1", "S100A10", "S100A11", "SACM1L", "SAFB", "SAMHD1", "SAP18", "SAR1A", "SARS", "SC5D", "SCAMP2", "SCARB1", "SCARB2", "SCD", "SCO1", "SCO2", "SCP2", "SCRIB", "SDCBP", "SDHA", "SDHB", "SEC23A", "SEC24A", "SEC24C", "SEC31A", "SEL1L", "SEPT11", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD7", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SFPQ", "SFSWAP", "SGPL1", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SHMT1", "SHMT2", "SHOC2", "SIN3A", "SIRT1", "SIRT2", "SKP1", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC30A5", "SLC35B2", "SLC3A2", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMS", "SMYD3", "SMYD5", "SNAP23", "SNAP29", "SND1", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SOAT1", "SOD2", "SPEN", "SPPL2A", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SREK1", "SRM", "SRP54", "SRPK1", "SRRM1", "SRSF1", "SRSF10", "SRSF3", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSR4", "STAG2", "STAM", "STAMBP", "STAT1", "STAT3", "STIM2", "STIP1", "STK4", "STMN1", "STRAP", "STRN", "STUB1", "STX4", "STXBP3", "STXBP4", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SULT2A1", "SUN1", "SUPT5H", "SUZ12", "SYNE2", "TAB1", "TACO1", "TALDO1", "TARDBP", "TBC1D4", "TBCA", "TBL2", "TCP1", "TDP2", "TECR", "TELO2", "TERF2IP", "TFAM", "TFRC", "THRAP3", "TIMELESS", "TJP1", "TK1", "TKT", "TLN1", "TMED10", "TMEM43", "TMOD3", "TMPO", "TMPO", "TNPO1", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOPBP1", "TOR1AIP1", "TP53", "TP53BP1", "TPI1", "TPM3", "TPM4", "TPP1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRIM25", "TRIM28", "TRIP13", "TRMT2A", "TSC2", "TSG101", "TSPYL1", "TTC19", "TTC26", "TTI1", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWISTNB", "TXNDC5", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UBA1", "UBA3", "UBAP2L", "UBE2L3", "UBE2N", "UBE2V1", "UBR5", "UBTF", "UCHL5", "UCK2", "UFD1", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119", "UNG", "UPF1", "UQCC1", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USMG5", "USP10", "USP5", "USP7", "USP9X", "UTRN", "VAPA", "VAPB", "VARS1", "VBP1", "VCL", "VDAC1", "VDAC2", "VDAC3", "VIM", "VPS18", "VPS33A", "VPS4A", "WAPL", "WARS", "WDHD1", "WDR1", "WDR5", "WDR73", "WFS1", "WIPI2", "XAB2", "XPNPEP3", "XPO1", "XPO5", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZC3H15", "ZFR", "ZFYVE16", "ZMPSTE24", "ZNF318", "ZYX"], "leading_proteins": ["AAR2", "ABCC4", "ACADSB", "ACOX1", "ACOX3", "ACTN2", "ADSL", "ADSS", "AKT1", "AKT1S1", "AKT2", "ALDH5A1", "ALDOA", "ANLN", "AP2A2", "APMAP", "ARFIP2", "ARHGDIA", "ATP5B", "ATP5C1", "ATP5H", "ATP5I", "ATP6", "ATP6V1C1", "ATPAF1", "ATPIF1", "ATRX", "BAIAP2", "BAX", "BCL10", "BCS1L", "C21orf59", "CAB39", "CAPN1", "CASP2", "CASP3", "CBFB", "CCNB1", "CD2AP", "CDK4", "CDKN2A", "CHEK2", "CHKA", "CHUK", "CNOT1", "COA3", "COL4A3BP", "COX4I1", "COX6C", "COX7C", "CPT2", "CTBP2", "CTNNB1", "CTSA", "CXADR", "CYP20A1", "CYP51A1", "DARS", "DAXX", "DCAF7", "DCTN4", "DERL1", "DHCR24", "DHFR", "DIAPH1", "DNMT1", "DSP", "DYNC1H1", "DYNC1LI2", "ECSIT", "EIF2AK2", "EIF2S1", "EIF4E", "ELOA", "ELOC", "ENO1", "ERCC2", "EXOC2", "EXOC4", "EXOC6", "EXOSC2", "EXOSC9", "FABP5", "FAU", "FH", "FKBP5", "FOXC1", "FSCN1", "G6PD", "GABARAPL2", "GAPDH", "GGCX", "GNAI2", "GNG5", "GOT1", "GPI", "GTPBP4", "H2AFX", "H2AFY2", "H4C1*", "HADHB", "HDAC1", "HK1", "HLTF", "HMGA1", "HMGB1", "HMOX1", "HSD17B10", "HSPB1", "IFT27", "IRF2BPL", "IVD", "JUP", "KDSR", "KMT2A", "LDHA", "LIG1", "LZTFL1", "MANF", "MAP2K1", "MAP2K2", "MAP3K7", "MAPK14", "MAPK3", "MARK2", "MCU", "ME2", "MECP2", "MFN2", "MRPL19", "MSN", "MTHFD2", "MTOR", "NAMPT", "NDUFA11", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF7", "NDUFB11", "NDUFB3", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV2", "NEFL", "NEFM", "NME2", "NUBPL", "OCRL", "OGDH", "PABPC1", "PARP2", "PC", "PCK2", "PDHB", "PDS5B", "PFDN5", "PFDN6", "PFKP", "PGAM1", "PGK1", "PGRMC2", "PISD", "PKM", "PKMYT1", "PMPCA", "PNPLA8", "POLA1", "POLD1", "POLE", "POLR1B", "POLR1C", "POLR2E", "PON2", "PPAT", "PPP1CA", "PPP1R10", "PPP3CA", "PRDX2", "PRKAA1", "PRKACA", "PRKAG1", "PRKAR1A", "PSAT1", "PSMB2", "PSMC6", "PSMD10", "PSMD14", "PSMD4", "PTGES2", "PTRH2", "PYCR1", "QKI", "RAB3B", "RAB5A", "RACGAP1", "RANBP9", "RASA1", "RBM14", "RBP1", "REXO2", "ROCK2", "RPA3", "RPL10A", "RPL12", "RPL13", "RPL22", "RPL23", "RPL23A", "RPL27", "RPL29", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL38", "RPL7", "RPL7A", "RPL9", "RPLP0", "RPLP2", "RPRD1B", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS18", "RPS19", "RPS2", "RPS3A", "RPS6", "RPS7", "RPS8", "RPS9", "RPSA", "RRM1", "RRM2", "RTCB", "RTN3", "SCARB1", "SERPINH1", "SGPL1", "SHMT2", "SIN3A", "SLC1A5", "SLC25A19", "SLC25A5", "SLC29A1", "SLC35B2", "SLC3A2", "SLTM", "SNAP29", "SNRPB2", "SOAT1", "SOD2", "SRM", "STAM", "STAT3", "STK4", "STMN1", "STUB1", "SUCLG2", "TAB1", "TALDO1", "TJP1", "TKT", "TLN1", "TOMM70", "TP53", "TPI1", "TRA2A", "TSPYL1", "TTC26", "TUBB4B", "TXNRD1", "UBA3", "UBE2N", "UCK2", "UNC119", "UNG", "UQCR10", "UQCRB", "UQCRQ", "WAPL", "YARS", "YARS2", "YWHAH", "ZMPSTE24", "ZNF318", "ZYX"]} \ No newline at end of file diff --git a/opencell_localization/advanced/idx2term.json b/opencell_localization/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..8e70aa4c31be38111157862e4ce49a437f454259 --- /dev/null +++ b/opencell_localization/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "nucleoplasm"} \ No newline at end of file diff --git a/opencell_localization/advanced/plot_0.png b/opencell_localization/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..678578b2800bf2ce40ecacddeef8d635b79c62ce --- /dev/null +++ b/opencell_localization/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:454dd4a49465a65e731f23da4b1badc9b97c0635db48b437bc41640814a657b3 +size 207071 diff --git a/opencell_localization/basic/idx2term.json b/opencell_localization/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..6fa5227b10fa2d6af9bace4f57861c6bf801940c --- /dev/null +++ b/opencell_localization/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "nucleoplasm", "1": "cytoplasmic", "2": "er", "3": "nucleolus_gc", "4": "cytoskeleton", "5": "nucleolus_fc_dfc", "6": "centrosome", "7": "nuclear_punctae", "8": "golgi"} \ No newline at end of file diff --git a/opencell_localization/basic/plot_0.png b/opencell_localization/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..8fa781cb1604783c860bb1771e349e8cf026063f --- /dev/null +++ b/opencell_localization/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3671acdbfab036bac2940597280cea1cf5415a3165f0a9ca3a20f9de7b0fe565 +size 134382 diff --git a/opencell_localization/basic/plot_1.png b/opencell_localization/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..31c053a075e355eb8e093f9477c2827e54cc32b6 --- /dev/null +++ b/opencell_localization/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1dcfd389b3a094917f28d5730c94e0aebed4d59bf7089ea997f738b0acf93b54 +size 131993 diff --git a/opencell_localization/basic/plot_2.png b/opencell_localization/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..0cf4982714339d3495e232ecc6e77761091d00ed --- /dev/null +++ b/opencell_localization/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:718b5bdeef58038a8e39f69e9d9e8ed00987d90f6774357592ee0726d2b08337 +size 130993 diff --git a/opencell_localization/basic/plot_3.png b/opencell_localization/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..2bb86918d8eeab647756b8b472759d9b1c175342 --- /dev/null +++ b/opencell_localization/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c282a02deab9e7c49de6c4b963c3ebc8b79e1b895922afbe807695ed28b61693 +size 132393 diff --git a/opencell_localization/basic/plot_4.png b/opencell_localization/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..103d771c2ed2dfe753f0fdf30149639c18bb68e5 --- /dev/null +++ b/opencell_localization/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:82c2299b012cb4ed3c359afc8001d6829007c666e278d43584999adadb611e57 +size 140318 diff --git a/opencell_localization/basic/plot_5.png b/opencell_localization/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..7d79abccac082b7a31d12609d43146e473a2e607 --- /dev/null +++ b/opencell_localization/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f6d7bbc5536251307f7014e35d146c8108d07615571739b437ceffc4fe0edfa9 +size 138946 diff --git a/opencell_localization/basic/plot_6.png b/opencell_localization/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..d39cb5df198fe268fe72f1a917309dffe0b36bac --- /dev/null +++ b/opencell_localization/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8ea6f08f77e433b74b5dabc0ac9b988fb6a944d0da30b6e68ae5b685cfe6a462 +size 143833 diff --git a/opencell_localization/basic/plot_7.png b/opencell_localization/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..acb640d4d9e93d749f2a82fb620c431d947f8333 --- /dev/null +++ b/opencell_localization/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b4938f91a5e94eba73cc889d6beda797e72d56c5de363f687d3c3872f3d2b4ae +size 145070 diff --git a/opencell_localization/basic/plot_8.png b/opencell_localization/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..733ceb25217089ad91eaf7ee50965b8bb8be026d --- /dev/null +++ b/opencell_localization/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bebc04ea2775c8c74dbdf75dd2085f81e3c3a9c7c2ad7a29e8590db444b6a494 +size 140666 diff --git a/opencell_localization/consensus.joblib b/opencell_localization/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..53bd973560f307bf055f77bc7ddc9833a2db12db --- /dev/null +++ b/opencell_localization/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:590620f6afbe34b39bc764f2019126f033883d61f00cbeaa3db256f065c17e08 +size 62745 diff --git a/opencell_localization/df_merge.tsv b/opencell_localization/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..46bb6baa056b978e99463501f86303519b44233c --- /dev/null +++ b/opencell_localization/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +nucleoplasm 64 335 2.170318978253904 0.0299826898824027 107.98058252427184 363.0461165048543 -0.509667527966177 0.5668492057415937 36.63238542323702 27.921792815732285 1.1069658442061727 0.352537539057648 1.0 0.0017122074444869 0.0033384747096353 1.1527209112727188e-05 4.667154667759386e-09 diff --git a/opencell_localization/metrics.json b/opencell_localization/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..33b9c99b5f765baa9f0acce0f9e0918eb4a36518 --- /dev/null +++ b/opencell_localization/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2772, + "annotations_size": 17, + "title": "Average number of proteins per term", + "value": 86.0 +} \ No newline at end of file diff --git a/opencell_localization/paths.json b/opencell_localization/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..bf67521b5b48f64c6f1e4fb1d83a19e3586068cc --- /dev/null +++ b/opencell_localization/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/opencell_localization/fragment/C321/C321_val_log2fc"} \ No newline at end of file diff --git a/opencell_localization/result.tsv b/opencell_localization/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..bbdf4f92c3b4a8e102fd55d74e3f1e006266b802 --- /dev/null +++ b/opencell_localization/result.tsv @@ -0,0 +1,13 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +nucleoplasm 0.3188418247242303 2.1703189782539036 0.0299826898824027 0.4039931726826408 0.4141237762532153 335 P68371,O75832,O95747,Q9UHY1,P19388,Q9C0E2,Q7KZI7,Q9Y237,Q9Y5P4,P07305,Q71SY5,P52294,Q14997,P18858,Q969T9,P57076,P54105,O75448,Q14004,P49721,Q13451,Q99661,O43237,P26038,Q96T37,P28370,O95429,O95456,P17096,O15397,P55036,O15498,P31749,Q16539,P28072,P31751,O75190,Q7L2H7,Q99640,Q8IV63,Q8NC96,P53365,Q00839,P62333,Q13043,O15212,Q9Y4P1,P05204,Q7Z5K2,P05455,O43633,P56545,Q96F86,Q9NVZ3,Q9BT73,Q9UI26,Q96S59,Q9H814,Q15427,P46379,P42574,O00139,O43592,Q16630 64 +cell_contact 0.5744779999203855 1.909583834086235 0.0561868181988194 0.6258354338678054 0.4141237762532153 21 Q9UQB8 1 +cytoplasmic 0.3052860126510006 1.7923265897995555 0.0730806663976262 0.7247590853339168 0.4141237762532153 375 Q9UQB8,O75832,O95747,Q9UHY1,Q9C0E2,Q7KZI7,Q9Y237,Q9Y5P4,P36507,Q5JTV8,P14635,Q969T9,P54105,Q13596,P49721,Q9P253,O43237,P04792,P26038,P62861,P28370,O95456,P55036,O43318,Q01968,P31749,P62269,P31751,O75190,Q9H074,Q8NC96,P53365,P20339,Q13043,Q9Y4P1,Q9Y3P9,Q8WUX9,P61353,P42766,Q96F86,Q9NVZ3,Q9BT73,Q9UI26,Q15427,P46379,P42574 46 +membrane 0.3875525424361712 1.4470817198074015 0.1478740372014484 0.9341486684569356 0.5613344888108193 70 Q7KZI7,Q9UQB8,P31749 3 +er 0.3628701015096514 1.3271411112732283 0.1844620081050743 0.9687714832437412 0.5613344888108193 79 Q8WUX9,O95674,Q15392,O75915,O15173,Q06136,Q8N4V1,Q8TCJ2,Q99640,Q96A33,Q9NPA0,O95470,Q16850,P04844 14 +nucleolus_gc 0.3705401554706884 1.2869318153888365 0.1981180548744068 0.9765643287091136 0.5613344888108193 72 Q9NY61,P61353,Q7KZI7,P42766,Q9Y237,Q8TCT8,Q9NZM5,O95478,P42696,P17096 10 +cytoskeleton 0.4007539597421558 1.0124551648932687 0.3113204735408872 0.998236839178866 0.7233467581299854 33 P68371,Q8WWK9,Q9BZD4,O00139,Q13043,P14635 6 +nucleolus_fc_dfc 0.4250058243977875 0.9518102230440574 0.341193236449965 0.9991703654393091 0.7233467581299854 21 Q96PK6,O15160,P19388,Q9H9Y6,O95602,Q969X6,O95429 7 +centrosome 0.3251557825019225 0.4127570923706626 0.6797845909538149 0.999999996086928 0.9031860786489372 30 Q04917,Q8WWK9,Q99661,O43237,Q9BZD4,O14745 6 +nuclear_punctae 0.2892661233773086 0.3984155212185669 0.6903239186428649 0.9999999977847116 0.9031860786489372 68 P18858,P54105,O75448,P19388,P56545,O75190 6 +golgi 0.3004506337829293 0.3979436719620375 0.6906717072021284 0.9999999978266284 0.9031860786489372 52 Q8TAD4,Q01968,Q8NBN3,Q9Y5P4,Q8IXU6,P53365 6 +nuclear_membrane 0.2444408000286875 0.0389664017169048 0.9689171758045156 1.0 1.0 31 Q9H074,Q9C0E2 2 diff --git a/opencell_localization/selections.json b/opencell_localization/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..379b40b589e4b218408952078de707d90532542a --- /dev/null +++ b/opencell_localization/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["big_aggregates", "cell_contact", "centrosome", "chromatin", "cytoplasmic", "cytoskeleton", "er", "focal_adhesions", "golgi", "membrane", "mitochondria", "nuclear_membrane", "nuclear_punctae", "nucleolus_fc_dfc", "nucleolus_gc", "nucleoplasm", "vesicles"], "available_proteins": ["AAMP", "AATF", "ABCE1", "ACAP2", "ACLY", "ACTN1", "ACTN4", "ACTR2", "AHCY", "AHSA1", "AKAP12", "AKR1A1", "AKT1", "AKT1S1", "AKT2", "ALDH9A1", "ANAPC16", "ANKRD17", "ANKRD28", "ANXA11", "AP2B1", "ARF4", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGEF7", "ARID1A", "ARL1", "ARL2", "ARL3", "ARL6IP4", "ARL6IP5", "ARL8B", "ARPC2", "ARPC3", "ATG3", "ATG4B", "ATL2", "ATP1A1", "ATP2B1", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATXN10", "ATXN2L", "BAG4", "BAG6", "BAIAP2", "BANF1", "BAZ1A", "BAZ1B", "BCAP31", "BET1", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOP1", "BPNT1", "BRD2", "BTF3", "BYSL", "C1orf123", "C21orf59", "CAD", "CALD1", "CANX", "CAPRIN1", "CAPZB", "CASP2", "CASP3", "CASP6", "CBX1", "CCAR1", "CCDC47", "CCDC86", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CD81", "CDC23", "CDC27", "CDC37", "CDC42", "CDK1", "CDK13", "CDK2", "CDK4", "CDKN2A", "CDS2", "CEP170", "CHEK2", "CHMP2A", "CHMP7", "CHUK", "CKAP2", "CKAP4", "CKAP5", "CKB", "CLASP2", "CLCN7", "CLINT1", "CLNS1A", "CLPTM1", "CLTA", "CLTC", "CNN2", "COIL", "COL4A3BP", "COMMD2", "COPA", "COPB2", "COPE", "COPG1", "COPG2", "COPZ1", "CORO1C", "CPSF6", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CTBP1", "CTBP2", "CTNNB1", "CTNNBL1", "CTPS1", "CTTN", "CYB5R3", "CYP51A1", "DAD1", "DBNL", "DCTN2", "DDB1", "DDOST", "DDX21", "DDX39B", "DDX47", "DDX5", "DDX56", "DDX6", "DHCR24", "DHX37", "DHX9", "DIAPH1", "DKC1", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB6", "DNAJC11", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1", "DNM1L", "DNM2", "DPH2", "DRG1", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "EBNA1BP2", "EBP", "EDC3", "EDC4", "EDF1", "EEF1G", "EFTUD2", "EIF2AK2", "EIF3B", "EIF3E", "EIF3G", "EIF3I", "EIF3K", "EIF3M", "EIF4A1", "EIF4A3", "EIF5", "EMC1", "EMC2", "EMC4", "EMC7", "EMC8", "EMG1", "ENO1", "ENY2", "ESD", "ESYT1", "EWSR1", "EZR", "FAM120A", "FASN", "FAU", "FBL", "FDPS", "FKBP5", "FKBP8", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAK", "GAPDH", "GAR1", "GBF1", "GDI1", "GDI2", "GET4", "GNL2", "GNL3", "GPR107", "GRB2", "GSPT1", "GTPBP4", "GYG1", "GYS1", "H1F0", "HDAC1", "HDAC2", "HEATR3", "HGS", "HLA-A", "HMGA1", "HMGB2", "HMGCS1", "HMGN2", "HNRNPA0", "HNRNPC", "HNRNPD", "HNRNPH1", "HNRNPL", "HNRNPU", "HSP90AA1", "HSP90AB1", "HSPA14", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPB1", "HSPBP1", "HSPH1", "IDI1", "IGF1R", "IGF2BP1", "IGF2BP3", "ILF3", "IMP3", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IST1", "KDSR", "KIAA0368", "KIF11", "KIF20A", "KIF22", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KLC1", "KLC2", "KLC4", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "LAMP1", "LAMTOR2", "LARP7", "LBR", "LDHA", "LDHB", "LEMD3", "LIG1", "LMAN1", "LMNA", "LMNB1", "LPCAT1", "LSM14A", "LSM14B", "LSS", "LTV1", "LZTS2", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MARK2", "MDH1", "MECP2", "MED17", "MED24", "MED25", "MFN2", "MIF", "MKI67", "MMGT1", "MPHOSPH10", "MRTO4", "MSH6", "MSN", "MTOR", "MVD", "MVK", "MYBBP1A", "MYH10", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO6", "NANS", "NAPA", "NAPG", "NCAPH", "NCK1", "NCKAP1", "NCL", "NCLN", "NECAP1", "NECAP2", "NEK9", "NEMF", "NHP2", "NIFK", "NOL11", "NOM1", "NONO", "NOP2", "NOP53", "NOP58", "NPM1", "NRBP1", "NSA2", "NSDHL", "NUCKS1", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP153", "NUP155", "NUP214", "NUP35", "NUP98", "NUTF2", "NVL", "NXF1", "OCRL", "OSBP", "OSBPL8", "OXSR1", "PABPC4", "PACSIN2", "PAIP1", "PAK2", "PARP1", "PASK", "PBK", "PCNA", "PDCD11", "PDCD6", "PDCD6IP", "PDCL3", "PES1", "PFDN6", "PFN1", "PGK1", "PGRMC1", "PGRMC2", "PHAX", "PHGDH", "PI4K2A", "PICALM", "PIK3C2A", "PIN4", "PKM", "PKMYT1", "PKN2", "PLK1", "PMPCA", "PMVK", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2E", "POLR2G", "POLR3A", "PPM1G", "PRKAA1", "PRKACA", "PRKDC", "PRPF19", "PRPF4B", "PRPF8", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTDSS1", "PTGES3", "PTK7", "PXN", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB24", "RAB35", "RAB3GAP2", "RAB5A", "RAB5B", "RAB7A", "RAB8B", "RABGAP1", "RABGGTA", "RAC1", "RACK1", "RAD21", "RAN", "RANBP1", "RANBP2", "RANBP9", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM25", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM8A", "RBMX", "REEP5", "RER1", "RHOA", "RHOG", "RNASEH2A", "RNF40", "RPL10A", "RPL11", "RPL13", "RPL19", "RPL27", "RPL35", "RPL4", "RPL5", "RPN1", "RPN2", "RPP30", "RPS11", "RPS14", "RPS16", "RPS18", "RPS6KA1", "RPS6KA3", "RRP1", "RSL1D1", "RTCB", "RTN4", "RUVBL1", "RUVBL2", "S100A10", "SACM1L", "SAE1", "SAR1A", "SARS", "SBDS", "SC5D", "SCAMP1", "SCAMP2", "SCD", "SCFD1", "SEC16A", "SEC22B", "SEC23A", "SEC24C", "SEC31A", "SEC61B", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SGPL1", "SH3GL1", "SH3GLB1", "SH3GLB2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A17", "SLC27A4", "SLC30A5", "SLC35F2", "SLC9A3R1", "SLK", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCE1", "SMC1A", "SMN1*", "SNRNP40", "SNRPA", "SNRPB2", "SNRPD2", "SNU13", "SNX1", "SNX2", "SNX27", "SNX3", "SNX5", "SPOUT1", "SPPL2A", "SPTLC1", "SPTLC2", "SRI", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPRA", "SRPRB", "SSB", "SSRP1", "STAG2", "STAM", "STIM2", "STIP1", "STK4", "STT3A", "STT3B", "STX10", "STX12", "STX18", "STX5", "STX7", "STX8", "SUPT16H", "SUPT5H", "SYAP1", "TARDBP", "TCF25", "TCOF1", "TFRC", "TIA1", "TJP1", "TMA16", "TMCO1", "TMED10", "TMED2", "TMEM192", "TMEM87A", "TMPO", "TMPO", "TNPO1", "TOMM20", "TOMM70", "TOP1", "TOP2A", "TOR1AIP1", "TPR", "TPT1", "TRAPPC11", "TRIM28", "TSG101", "TSR1", "TTK", "TUBB4B", "TWISTNB", "U2AF2", "U2SURP", "UBA1", "UBE2M", "UBTF", "UFC1", "UGDH", "UPF1", "USP10", "USP7", "UTP14A", "UTP4", "UTP6", "UTRN", "VAPA", "VAPB", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VPS18", "VPS29", "VPS33A", "VPS35", "VPS4A", "VRK3", "WAPL", "WBP2", "WDR3", "WDR46", "WDR75", "XPO1", "XPO4", "XPO5", "XPOT", "YKT6", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZNF326", "ZNF598", "ZYX"], "leading_proteins": ["AATF", "AKT1", "AKT2", "ARFIP2", "ARL6IP5", "ATG4B", "BAG4", "BAG6", "BAIAP2", "C21orf59", "CASP3", "CCDC47", "CCNB1", "CDK13", "CDS2", "CHMP2A", "CHMP7", "CKAP2", "CLNS1A", "COL4A3BP", "CPSF6", "CTBP2", "CYP51A1", "DHCR24", "DNAJB6", "DYNC1LI2", "EDC3", "EIF3M", "EMC7", "FAU", "FKBP5", "H1F0", "HMGA1", "HMGN2", "HNRNPU", "HSPB1", "IPO11", "IPO8", "KDSR", "KIF2A", "KIF2C", "KPNA1", "LIG1", "MAP2K2", "MAP3K7", "MAPK14", "MARK2", "MED24", "MED25", "MMGT1", "MSN", "NECAP1", "NECAP2", "NOP53", "NRBP1", "NSA2", "NUF2", "OCRL", "OXSR1", "PAIP1", "PFDN6", "PGRMC2", "PHAX", "PIN4", "PKMYT1", "POLR1A", "POLR1B", "POLR1C", "POLR2E", "PSMB2", "PSMB6", "PSMC6", "PSMD10", "PSMD4", "PSME4", "PSMG1", "PSMG3", "RAB5A", "RABGAP1", "RANBP9", "RBM14", "RBM15", "RBM34", "RPL27", "RPL35", "RPN2", "RPS18", "SF3B4", "SGPL1", "SLC30A5", "SLC35F2", "SLC9A3R1", "SMARCA1", "SNX1", "SPPL2A", "SSB", "STK4", "STT3B", "TMEM87A", "TOR1AIP1", "TUBB4B", "UTP4", "VPS18", "VRK3", "WAPL", "WBP2", "XPO4", "XPOT", "YKT6", "YWHAH"]} \ No newline at end of file diff --git a/panther_protein_class/advanced/idx2term.json b/panther_protein_class/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..a04cb347ecf8e151fcfe132e5f934d5a411fcb01 --- /dev/null +++ b/panther_protein_class/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "oxidoreductase"} \ No newline at end of file diff --git a/panther_protein_class/advanced/plot_0.png b/panther_protein_class/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..c9d91f989602944af56d6eb355923a66889c2109 --- /dev/null +++ b/panther_protein_class/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:36f1cb9257bb3322441fb9f3e892b7644273f5d84905958b2d098c72ac635695 +size 204442 diff --git a/panther_protein_class/basic/idx2term.json b/panther_protein_class/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9b0afc2ecc865961094f4b0c52aea597db8b1abd --- /dev/null +++ b/panther_protein_class/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "oxidoreductase", "1": "non-receptor serine/threonine protein kinase", "2": "histone", "3": "membrane traffic protein", "4": "transporter", "5": "ribosomal protein", "6": "non-motor microtubule binding protein", "7": "scaffold/adaptor protein", "8": "oxidase", "9": "lyase", "10": "microtubule binding motor protein", "11": "translation initiation factor", "12": "metalloprotease", "13": "actin or actin-binding cytoskeletal protein", "14": "chaperone"} \ No newline at end of file diff --git a/panther_protein_class/basic/plot_0.png b/panther_protein_class/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..6a2552d3cf0bca99a53d9da721d8185277c7a928 --- /dev/null +++ b/panther_protein_class/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2ef71328aa2bb44a48f77a2df8f5dea08546a758b4faace9bd787c009e07cfc5 +size 133141 diff --git a/panther_protein_class/basic/plot_1.png b/panther_protein_class/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..c29328c58a94ef8073af3fd2ae063a2835c46493 --- /dev/null +++ b/panther_protein_class/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f2981f5af00e43fda2ea9d49291da44cf3a7d889b0b44f2b82865b5bb8ec78ee +size 138165 diff --git a/panther_protein_class/basic/plot_10.png b/panther_protein_class/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..631649e5cba39c6fe0adda1bce8bdec17e5c97f1 --- /dev/null +++ b/panther_protein_class/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:17de7ae94750b57f48880e7e4b89ec6ac91e3de6eecf7eb4083ac818ee8af9ec +size 148815 diff --git a/panther_protein_class/basic/plot_11.png b/panther_protein_class/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..7f277714bf731493b77e45b876544ce13e4ce9fd --- /dev/null +++ b/panther_protein_class/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a4b865711e288f8568acca481c18b732024cae9aa4063e133a2202242be62b31 +size 150802 diff --git a/panther_protein_class/basic/plot_12.png b/panther_protein_class/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..87e7211269d44d97f37c48e3dc2b69d41da51f18 --- /dev/null +++ b/panther_protein_class/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d76b65c5930eecab2a71c1a7901f3b1bb3ee8ad55e4d1374affd32450366e23c +size 146711 diff --git a/panther_protein_class/basic/plot_13.png b/panther_protein_class/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..38915dd859b2f880d469be18be5d039651b75b61 --- /dev/null +++ b/panther_protein_class/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3b66bdace902ef3371b60728346a1661f1f0799973d8b924d6de15e631ca0814 +size 155844 diff --git a/panther_protein_class/basic/plot_14.png b/panther_protein_class/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..fe0435b096c65abd893a252b5eb36a744895e8ae --- /dev/null +++ b/panther_protein_class/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:46deae28035a3d398441067265e11dec8e6ce4e83d8210d31812da07562fd5ec +size 143025 diff --git a/panther_protein_class/basic/plot_2.png b/panther_protein_class/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..90e550714b8a0b342e8f3f004d13bac53cbc14be --- /dev/null +++ b/panther_protein_class/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:db6bd1309d3591f05e880954359b7df37cd2bea7e18dc4189df500ed93f493b4 +size 123950 diff --git a/panther_protein_class/basic/plot_3.png b/panther_protein_class/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..6b094bf26c6bbca35b6b0e64408d12ce958de81c --- /dev/null +++ b/panther_protein_class/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fc2d1ad7a62e6e431c0776409d47eff41bcf5da05c15e123c4da60df5cb10ea7 +size 140094 diff --git a/panther_protein_class/basic/plot_4.png b/panther_protein_class/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..2e4dd7bf75c012cc24a522eeea7740aa6e14c5ee --- /dev/null +++ b/panther_protein_class/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2b387cd3ee220485c5151a36c79a5330f74efc85a8ea613f0b33fe6070e41f94 +size 132445 diff --git a/panther_protein_class/basic/plot_5.png b/panther_protein_class/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..912da96890a4792c14ffaa0f80ccf6e76365c0ba --- /dev/null +++ b/panther_protein_class/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:441cdfeb1144ae3bbcb0981b9d6bf6f37c81711f5b30c5c7abd430f7695d6551 +size 143213 diff --git a/panther_protein_class/basic/plot_6.png b/panther_protein_class/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..e9ecaaa90d08a060caab4ec427446aa8e7ffa3d6 --- /dev/null +++ b/panther_protein_class/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:11f4fae67e00c5d66ac841934e83e40dd456145b2b2e030d06cc0bc57a16a8c4 +size 141228 diff --git a/panther_protein_class/basic/plot_7.png b/panther_protein_class/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..9f4da4b44c095c632985dc21d77c3b9e372623c8 --- /dev/null +++ b/panther_protein_class/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b2a031087c4dc6c3f31a2aabdcb7c72812e71555a1424f44b2fee06dd6cd4a93 +size 147592 diff --git a/panther_protein_class/basic/plot_8.png b/panther_protein_class/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..f7d549f4f04afedfefe332c53f115b098faec345 --- /dev/null +++ b/panther_protein_class/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:dc77d9df328977aa1223bb230af18cb3d4c0e0279c7c2bb5ac06b048bd808b31 +size 140928 diff --git a/panther_protein_class/basic/plot_9.png b/panther_protein_class/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..76727cab43ce07efecd282625e91366254c0c996 --- /dev/null +++ b/panther_protein_class/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:03de7b51adff4d0518911c45315a5ee90d5b135f50fa33b040eb4bfbcf9a474c +size 130737 diff --git a/panther_protein_class/consensus.joblib b/panther_protein_class/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..417c20c40d2344793881c4e3d61e93e2bdd7faa5 --- /dev/null +++ b/panther_protein_class/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:be40c8571b57f6ee652c120987932157ddf3d1bd495117a308fc4c15dc3a10bd +size 73175 diff --git a/panther_protein_class/df_merge.tsv b/panther_protein_class/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..f3dad4334b5bc7c4528a7a35e148c213623436c1 --- /dev/null +++ b/panther_protein_class/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +oxidoreductase 13 40 2.4542745432642232 0.0141169156651881 12.558252427184469 43.60436893203884 0.9664652969079414 0.3656199292680728 5.072676172192643 3.8442089013841825 1.3118377214144643 0.3470065139863294 1.0 0.0735221210966126 0.2182423914373472 0.0070033640676979 0.0001514772514271 diff --git a/panther_protein_class/metrics.json b/panther_protein_class/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..ce1d03e8b21786d280b9c2c87a6ff78798736426 --- /dev/null +++ b/panther_protein_class/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2772, + "annotations_size": 156, + "title": "Average number of proteins per term", + "value": 12.365384615384615 +} \ No newline at end of file diff --git a/panther_protein_class/paths.json b/panther_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..a063294ffbae62722a081b978db783d25118a728 --- /dev/null +++ b/panther_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/panther_protein_class/fragment/C321/C321_val_log2fc"} \ No newline at end of file diff --git a/panther_protein_class/result.tsv b/panther_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..4e52a194242758b58d3b077969a4d2a3f7598f97 --- /dev/null +++ b/panther_protein_class/result.tsv @@ -0,0 +1,54 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +oxidoreductase 0.5415885304650149 2.4542745432642232 0.0141169156651881 0.8911659586169532 0.1159073075668078 40 O43169,Q13630,P22570,P51970,Q15067,O15254,O43676,Q86Y39,Q8N4Q0,O43396,P04179,Q9NX14,O14949 13 +non-receptor serine/threonine protein kinase 0.4884794164322664 1.9257928128423936 0.0541302492448432 0.9998302973825262 0.2638849650686107 37 O43318,Q9UHY1,Q14004,P31749,Q7KZI7,Q16539,P31751,Q99640,Q8IV63,Q99986,P36507,Q13043 12 +DNA glycosylase 0.815884476534294 1.896846391232144 0.0578482145151788 0.9999081970625514 0.2658830159021768 2 P13051 1 +ATP-binding cassette (ABC) transporter 0.7770485150666886 1.896084571095448 0.057948862440218 0.9999097143727328 0.2658830159021768 8 O15439,P33527,O75027,Q8NC96 4 +oxygenase 0.7776758259951294 1.785727404675702 0.0741434059074044 0.9999939630031616 0.3043781926725024 7 Q16850,P30519,Q6UW02 3 +histone 0.7037997707367543 1.6744081812391192 0.0940504060276428 0.9999997966569136 0.3762016241105712 9 P10412,P62805,P16403,P16104,Q92522,P07305,Q9P0M6 7 +membrane traffic protein 0.4361907204636506 1.6459909250339124 0.0997656274059388 0.9999999242343752 0.3890859468831616 52 Q9H4M9,Q8WUX9,A6NIH7,Q13432,Q10567,O94973,Q96RL7,P20645,P40222,Q5JRA6,Q96A65,O75436 12 +kinase 0.5400149543358428 1.5390424513279268 0.1237939329141699 0.9999999988867928 0.4108905007363939 18 O00764,Q16822,P35790 3 +ATP synthase 0.4965617621997946 1.3636873500465698 0.172665987050971 0.999999999999856 0.4988128514805829 20 P21281,P00846 2 +transporter 0.4004103595518776 1.33961738541895 0.1803697686881 0.9999999999999666 0.5115942530062474 55 O60830,P54105,Q99595,Q9C0E2,Q9UI26,Q15070 6 +transfer/carrier protein 0.5641611719895145 1.3081861413363929 0.190810181490608 0.9999999999999954 0.522217338816401 12 Q9Y5P4 1 +membrane trafficking regulatory protein 0.5103778337184903 1.2622488077314151 0.206859271030904 0.9999999999999998 0.5440281217210146 15 O43760,Q8WTV0 2 +secondary carrier transporter 0.5879197063199005 1.2316446752585188 0.2180818447395487 1.0 0.5448620863344191 10 O95202,Q8TB61,Q9BQT8 3 +G-protein coupled receptor 0.8145250864689179 1.1990240993601884 0.2305185749876388 1.0 0.5448620863344191 3 Q8NBN3 1 +amino acid transporter 0.788439874123946 1.103429723816746 0.2698405945283797 1.0 0.5858156429010185 3 O75915 1 +ribosomal protein 0.3341734263533945 1.0978585301791766 0.2722662687182544 1.0 0.5858156429010185 113 P62906,Q9Y3D9,P18077,Q6P1L8,Q8N5C6,P52815,P62249,P62910,Q9Y3U8,P62899,Q9Y2R5,P62753,P62424,P82664,P62841,Q9NRX2,P32969,P62263,P62081,P15880,P30050,Q9BRJ2,P82673,P62241,Q13084,Q8N5N7,P35268,P82675,P62244,P62269,Q9BYD2,P39019,P62750,P61247,P08865,Q9NQ50,P05388,P61353,P42766,P18124,Q9Y2Q9,P05387 42 +primase 0.6382671480144364 1.0779263067268567 0.2810666444640453 1.0 0.5925188721133928 2 P49642 1 +glycosyltransferase 0.4523440463598511 0.9527178297032664 0.3407330570808971 1.0 0.656597574647502 16 Q8TCJ2,O60762,Q9NYU2,P04844 4 +acyltransferase 0.4522617987942008 0.9324005610806484 0.3511295549401283 1.0 0.6652662151202783 15 Q8NCC3 1 +G-protein 0.7229046242774554 0.9269437455391728 0.353955742660148 1.0 0.6652662151202783 4 P18085,P08240,P40616 3 +primary active transporter 0.4054727911608218 0.7931439395408566 0.4276939651554516 1.0 0.7496658265646119 20 Q9BUN8,Q9NS69 2 +non-motor microtubule binding protein 0.4140713494220002 0.7596108566044474 0.4474872277152146 1.0 0.7756445280397055 17 Q8WWK9,Q9BZD4,Q96CW5,P60520,O94901,O43663 6 +homeodomain transcription factor 0.5581227436823052 0.7217363836578994 0.4704565683110948 1.0 0.7977307027883782 2 Q13330 1 +scaffold/adaptor protein 0.3188647472195633 0.6988858994921515 0.4846233402072193 1.0 0.8093502273714995 70 P57105,Q9UQB8,Q96JJ3,Q04917,Q13596,Q9BQ95,Q02952,Q9Y639,Q15404,Q9Y2W6,Q96CX2,Q9UQ13,Q96S59,Q96L92,Q9NWT1,Q92783 16 +oxidase 0.40809328172588 0.6894937750088872 0.49051258926549 1.0 0.8093502273714995 15 P13073,P36551,P15954,O60341,O75880,Q15800,Q8NB78,P50336 8 +lyase 0.438104338960914 0.6712433420798855 0.5020655218425225 1.0 0.8127005265043562 12 Q9BU89,P07954,Q04760,Q9Y606,Q9UHG3 5 +G-protein modulator 0.643231276641147 0.6507458215593037 0.5152105789143608 1.0 0.8127005265043562 4 P52565 1 +serine protease 0.3865125378053713 0.5892703996624514 0.5556798980849655 1.0 0.814101304594441 16 Q8N2K0,O14773 2 +heterotrimeric G-protein 0.4879759525694211 0.5774898467744018 0.5636085954884591 1.0 0.814101304594441 7 P04899 1 +Hsp90 family chaperone 0.5868803853317258 0.4722954870277888 0.6367158911733246 1.0 0.8868542769914164 4 Q12931,P08238 2 +GTPase-activating protein 0.3598818783165237 0.4444126351522843 0.6567442799986973 1.0 0.8901597610497839 15 Q9H0H5,P20936 2 +methyltransferase 0.3843195632701273 0.4274336098226411 0.6690635316273963 1.0 0.8901597610497839 12 P22061 1 +microtubule binding motor protein 0.3504621859162817 0.4215877172876119 0.6733259731017596 1.0 0.8901597610497839 17 Q02241,Q9UJW0,O95239,Q12756,Q14204,Q99661,O00139 7 +kinase modulator 0.5495453256821681 0.3660456427026786 0.7143310175348483 1.0 0.892426290488126 4 P10644,P54619 2 +translation release factor 0.5652566495551647 0.365035149247827 0.7150851686603574 1.0 0.892426290488126 3 Q96E11 1 +translation initiation factor 0.2850209267344785 0.2800760296839031 0.7794191745790695 1.0 0.9499171190182408 45 O00487,Q86U42,Q04637,Q9UJA5,Q14152,P46199,O43583,Q9ULC4,O00303,P42696 10 +ligase 0.3062697177401071 0.2711319361184374 0.7862895597290986 1.0 0.9508617931607704 24 Q9HCC0 1 +metalloprotease 0.2973979079485281 0.2411114329544368 0.8094687519279835 1.0 0.97136250231358 27 O75844,Q7Z2K6,P28838,Q99797,Q10713,Q9NZ08,Q96TA2 7 +microtubule or microtubule-binding cytoskeletal protein 0.3434254474260992 0.2057016624601157 0.8370239598762272 1.0 0.9892803668893828 10 O43237 1 +protein phosphatase 0.300806377856493 0.2025764286403461 0.8394661152153728 1.0 0.9892803668893828 16 Q08209,Q9H0C8,P49593,Q15750 4 +DNA-binding transcription factor 0.2966205790995534 0.1975145094569292 0.8434249281813326 1.0 0.9892803668893828 18 Q13951,P46100,Q86YP4,Q9UHR5 4 +cytoskeletal protein 0.3787793426569537 0.1779813235389526 0.858737643212528 1.0 0.99517905897184 5 Q9UHD8,Q14141 2 +RNA helicase 0.3283249919803479 0.1654026018427692 0.8686271059084398 1.0 0.99517905897184 10 Q9H2U1,Q9H6S0,Q7L2E3,Q7Z478 4 +tubulin 0.3559066808906926 0.145837185258275 0.884049920122407 1.0 0.99517905897184 6 P68371,P04350,Q13885 3 +DNA metabolism protein 0.2629982227519039 0.117792829528044 0.9062318112007716 1.0 0.99517905897184 34 Q04837,P51608,Q9UGN5,Q07864 4 +general transcription factor 0.2691999331153783 0.1094749636118086 0.9128257785434092 1.0 0.99517905897184 19 Q71SY5 1 +actin or actin-binding cytoskeletal protein 0.2680467942005589 0.1060033355582566 0.9155797057070008 1.0 0.99517905897184 19 Q6WCQ1,Q01518,O15145,P35241,Q15942,P26038 6 +basic leucine zipper transcription factor 0.4012184763068803 0.0711125635548231 0.94330816921585 1.0 0.99517905897184 3 Q9Y6E2 1 +chaperone 0.2461816563506679 0.0668250649921523 0.9467209690278188 1.0 0.99517905897184 63 Q9Y680,Q14318,P30533,Q99426,Q9Y3C6,Q13451,Q9Y2R0,Q5TC12,O95456,Q96EY1,Q99471,O14967,O15260,Q9NVA1,P27797,Q9BT73,Q8WXX5,P46379,Q9H1K1 19 +esterase 0.28696059117847 0.0550275773072583 0.9561164935584774 1.0 0.99517905897184 7 Q9NUJ1,Q9H0P0 2 +transaminase 0.2452998122871008 0.0285307611776615 0.9772388341382152 1.0 0.99517905897184 11 P17174,Q8TD30,O15382 3 +zinc finger transcription factor 0.2843208092485589 0.0191316139630587 0.9847361117459504 1.0 0.99517905897184 4 Q2TAL8,Q5VZL5,Q9H1B7 3 +peroxidase 0.2337427745664785 0.0140379478237313 0.9887997060297128 1.0 0.99517905897184 4 P30041,P30048,P32119 3 diff --git a/panther_protein_class/selections.json b/panther_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..ce059ea87a0dc9ef233b1f5c63b31e8d8365f5ad --- /dev/null +++ b/panther_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthase", "ATP-binding cassette (ABC) transporter", "C2H2 zinc finger transcription factor", "DNA glycosylase", "DNA helicase", "DNA ligase", "DNA metabolism protein", "DNA methyltransferase", "DNA polymerase processivity factor", "DNA topoisomerase", "DNA-binding transcription factor", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "G-protein", "G-protein coupled receptor", "G-protein modulator", "GTPase-activating protein", "Hsp90 family chaperone", "P53-like transcription factor", "RNA helicase", "RNA metabolism protein", "RNA methyltransferase", "RNA processing factor", "RNA splicing factor", "SNARE protein", "acetyltransferase", "actin and actin related protein", "actin binding motor protein", "actin or actin-binding cytoskeletal protein", "acyltransferase", "aldolase", "amino acid kinase", "amino acid transporter", "aminoacyl-tRNA synthetase", "antimicrobial response protein", "apolipoprotein", "aspartic protease", "basic leucine zipper transcription factor", "cadherin", "calcium-binding protein", "calmodulin-related", "carbohydrate kinase", "cell adhesion molecule", "centromere DNA-binding protein", "chaperone", "chaperonin", "chromatin/chromatin-binding, or -regulatory protein", "cyclase", "cysteine protease", "cytokine", "cytoskeletal protein", "damaged DNA-binding protein", "deaminase", "decarboxylase", "defense/immunity protein", "dehydratase", "dehydrogenase", "endodeoxyribonuclease", "endoribonuclease", "epimerase/racemase", "esterase", "exodeoxyribonuclease", "exoribonuclease", "extracellular matrix glycoprotein", "extracellular matrix protein", "galactosidase", "general transcription factor", "glucosidase", "glycosidase", "glycosyltransferase", "growth factor", "guanyl-nucleotide exchange factor", "heterotrimeric G-protein", "histone", "histone modifying enzyme", "homeodomain transcription factor", "hydratase", "hydrolase", "immunoglobulin receptor superfamily", "integrin", "intercellular signal molecule", "intermediate filament binding protein", "ion channel", "isomerase", "kinase", "kinase activator", "kinase inhibitor", "kinase modulator", "ligase", "lipase", "lyase", "mRNA capping factor", "mRNA polyadenylation factor", "major histocompatibility complex protein", "membrane traffic protein", "membrane trafficking regulatory protein", "metalloprotease", "methyltransferase", "microtubule binding motor protein", "microtubule or microtubule-binding cytoskeletal protein", "mitochondrial carrier protein", "mutase", "non-motor actin binding protein", "non-motor microtubule binding protein", "non-receptor serine/threonine protein kinase", "nucleic acid metabolism protein", "nucleotide kinase", "nucleotide phosphatase", "nucleotidyltransferase", "oxidase", "oxidoreductase", "oxygenase", "peptide hormone", "peroxidase", "phosphatase", "phosphatase activator", "phosphatase modulator", "phosphodiesterase", "phospholipase", "primary active transporter", "primase", "protease", "protease inhibitor", "protein modifying enzyme", "protein phosphatase", "protein-binding activity modulator", "pyrophosphatase", "reductase", "replication origin binding protein", "ribosomal protein", "scaffold/adaptor protein", "secondary carrier transporter", "serine protease", "small GTPase", "structural protein", "tight junction", "transaminase", "transcription cofactor", "transfer/carrier protein", "transferase", "transketolase", "translation elongation factor", "translation factor", "translation initiation factor", "translation release factor", "translational protein", "transmembrane signal receptor", "transporter", "tubulin", "tyrosine protein kinase receptor", "ubiquitin-protein ligase", "vesicle coat protein", "viral or transposable element protein", "voltage-gated ion channel", "winged helix/forkhead transcription factor", "zinc finger transcription factor"], "available_proteins": ["AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCC1", "ABCC4", "ABCD3", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD6", "ACAA1", "ACAA2", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACLY", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADH5", "ADI1", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGPAT1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP8", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALKBH5", "ALYREF", "ANAPC7", "ANKFY1", "ANKHD1", "ANKRD17", "ANKRD28", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP3B1", "AP3D1", "AP3M1", "APEH", "APOL2", "APRT", "ARCN1", "ARF4", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP5", "ARHGDIA", "ARHGEF1", "ARHGEF7", "ARIH1", "ARL1", "ARL6IP5", "ARPC1A", "ARPC1B", "ARPC3", "ARPC4", "ARPC5", "AS3MT", "ASAH1", "ASCC3", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD5", "ATG3", "ATG4B", "ATL2", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "ATP7B", "ATPAF1", "ATPIF1", "ATRX", "ATXN2L", "AUP1", "B4GAT1", "BAG2", "BAG6", "BAIAP2", "BAP18", "BCAP31", "BCAS2", "BCAT2", "BCLAF1", "BET1", "BLMH", "BLVRA", "BLVRB", "BOP1", "BPNT1", "BRIX1", "BSG", "BTF3", "BUB3", "BUD31", "BZW1", "BZW2", "CACYBP", "CAD", "CALD1", "CALR", "CALU", "CAND1", "CANX", "CAP1", "CAPN1", "CAPRIN1", "CAPZA1", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP2", "CASP3", "CASP6", "CAST", "CBFB", "CBR1", "CCAR1", "CCAR2", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD276", "CD2BP2", "CD47", "CDC23", "CDC27", "CDC37", "CDC42", "CDC45", "CDK1", "CDK13", "CDK2", "CDK4", "CDK6", "CDKN2AIP", "CDS2", "CEBPZ", "CEP170", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHEK2", "CHERP", "CHKA", "CHMP2A", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHUK", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP2", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLNS1A", "CLP1", "CLPB", "CLPP", "CLPX", "CLTA", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT7", "CNP", "COA3", "COASY", "COIL", "COL4A3BP", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "CORO1C", "COTL1", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7C", "CPD", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZL1", "CS", "CSE1L", "CSNK1A1", "CSNK2B", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWC22", "CYB5B", "CYB5D2", "CYB5R3", "CYFIP1", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DBN1", "DBNL", "DCAF13", "DCAKD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCXR", "DDB1", "DDI2", "DDOST", "DEK", "DENR", "DERL1", "DERL2", "DGCR8", "DHCR24", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX40", "DHX8", "DHX9", "DIDO1", "DIEXF", "DIS3", "DIS3L2", "DKC1", "DLAT", "DLD", "DLST", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOHH", "DPF2", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUSP12", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "EARS2", "EBP", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC4", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EHD1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP3", "EMC2", "EMG1", "ENO1", "ENOPH1", "ENY2", "EPHX1", "EPHX2", "EPPK1", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERC1", "ERCC2", "ERH", "ERI1", "ERMP1", "ERO1A", "ERP29", "ESD", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "FAHD1", "FAHD2A", "FAM3C", "FAM98A", "FAM98B", "FARSA", "FARSB", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FKBP14", "FKBP1A", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLII", "FMR1", "FN3KRP", "FNDC3A", "FNTA", "FNTB", "FOXC1", "FOXRED1", "FRG1", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATAD2A", "GATAD2B", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLM", "GCN1", "GDI1", "GDI2", "GDPD1", "GFPT1", "GGH", "GINS1", "GINS2", "GLA", "GLB1", "GLDC", "GLMN", "GLO1", "GLRX3", "GLRX5", "GLS", "GLTP", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNE", "GNG12", "GNG5", "GNPDA1", "GNS", "GOLGA3", "GOPC", "GOT1", "GOT2", "GPATCH4", "GPD2", "GPI", "GPKOW", "GPR107", "GPR108", "GPT2", "GRHPR", "GRPEL1", "GRSF1", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2E1", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C5", "GTPBP1", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADHB", "HAT1", "HBS1L", "HCCS", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HECTD1", "HERC2", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HM13", "HMGA1", "HMGCL", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HP1BP3", "HPRT1", "HSD17B10", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HTATSF1", "HUWE1", "IARS", "IARS2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "ILF2", "ILF3", "ILKAP", "ILVBL", "IMP3", "IMPAD1", "IMPDH2", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IRF2BPL", "ISCU", "ISOC1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPK1", "IVD", "KARS", "KAT7", "KCTD12", "KDELR1", "KDM1A", "KDM1B", "KDM3B", "KDSR", "KHDRBS1", "KHSRP", "KIAA0368", "KIF11", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KLC1", "KLC2", "KLC4", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRR1", "KYAT3", "L2HGDH", "LAMP1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LBR", "LCLAT1", "LDAH", "LDHA", "LDHB", "LENG8", "LETM1", "LGALS3", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LNPEP", "LONP1", "LPCAT1", "LPGAT1", "LRPAP1", "LRRC40", "LRRC47", "LRRC59", "LRWD1", "LSM14A", "LSM14B", "LSM2", "LSM6", "LSS", "LTN1", "LYAR", "LYPLA1", "LZTFL1", "M6PR", "MACF1", "MAGED2", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARK2", "MARS", "MAT2A", "MAT2B", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED17", "MED24", "MED25", "METTL1", "METTL13", "MFSD5", "MGEA5", "MGST2", "MGST3", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MIPEP", "MMAB", "MMS19", "MOGS", "MORF4L1", "MORF4L2", "MPG", "MPHOSPH10", "MPI", "MPP2", "MPP6", "MPRIP", "MPST", "MPV17L2", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL44", "MRPL45", "MRPL46", "MRPL50", "MRPL58", "MRPL9", "MRPS10", "MRPS15", "MRPS17", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTIF2", "MTMR6", "MTOR", "MTPAP", "MUT", "MVD", "MVK", "MYBBP1A", "MYDGF", "MYEF2", "MYG1", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA25", "NAA35", "NAA50", "NAE1", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCBP1", "NCDN", "NCK1", "NCOA5", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4", "NENF", "NFS1", "NHP2", "NIP7", "NKRF", "NKTR", "NLN", "NLRX1", "NME1", "NME2", "NMT1", "NNT", "NOC4L", "NOL6", "NOL9", "NOM1", "NONO", "NOP14", "NOP56", "NOP58", "NOVA2", "NPEPPS", "NPM1", "NPTN", "NRBP1", "NRDC", "NSDHL", "NSF", "NSFL1C", "NSUN2", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDCD2", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUF2", "NUMA1", "NUP107", "NUP153", "NUP155", "NUP160", "NUP210", "NUP214", "NUP37", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "NXN", "OAT", "OCIAD1", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC3", "OSGEP", "OTUB1", "OTUD4", "OXA1L", "P3H1", "P4HA1", "P4HB", "PA2G4", "PABPN1", "PACSIN2", "PAFAH1B2", "PAFAH1B3", "PAIP1", "PAK1IP1", "PAK2", "PALLD", "PANK4", "PAPOLA", "PARN", "PARP1", "PARP2", "PASK", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDS5A", "PDS5B", "PDXK", "PEBP1", "PECR", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHF3", "PHF6", "PHGDH", "PI4K2A", "PICALM", "PIK3C2A", "PIN1", "PINX1", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN2", "PLA2G15", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PMVK", "PNP", "PNPLA6", "PNPLA8", "PNPO", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLDIP3", "POLE", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLRMT", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPIB", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R1", "PPP5C", "PPT1", "PPT2", "PQBP1", "PRAF2", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF39", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PUF60", "PUM1", "PURA", "PUS1", "PWP1", "PXN", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB3GAP1", "RAB3GAP2", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RAD23B", "RAE1", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RASA1", "RAVER1", "RBBP6", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM26", "RBM27", "RBM34", "RBM4", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "REEP5", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RNASEH2A", "RNF14", "RNMT", "RNPS1", "ROCK2", "RP2", "RPA1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RRM1", "RRM2", "RRS1", "RSF1", "RSL1D1", "RSU1", "RTN4IP1", "S100A10", "S100A11", "SACM1L", "SAE1", "SAMHD1", "SAP18", "SAP30BP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SDCBP", "SDE2", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC23A", "SEC23IP", "SEC24A", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC63", "SEH1L", "SENP3", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD7", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN4", "SHMT1", "SHMT2", "SHOC2", "SIGMAR1", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC35B2", "SLC4A1AP", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCE1", "SMC6", "SMN1*", "SMNDC1", "SMPD4", "SMYD3", "SNAP23", "SNAP29", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SNX27", "SNX5", "SNX6", "SOAT1", "SOD2", "SON", "SORD", "SPAG9", "SPCS2", "SPCS3", "SPEN", "SPOUT1", "SPPL2A", "SPR", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SREK1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "STAG2", "STAM", "STAMBP", "STAT1", "STAT3", "STK4", "STOML2", "STRAP", "STRBP", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX17", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SULT2A1", "SUN1", "SUN2", "SUPT16H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYNCRIP", "SYNGR2", "SYNJ2BP", "TAB1", "TAF15", "TAGLN2", "TALDO1", "TARS", "TARS2", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL3", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TDRKH", "TECR", "TERF2IP", "TES", "TFG", "TFIP11", "TFRC", "TGOLN2", "THOC1", "THOC3", "THOP1", "THRAP3", "THUMPD3", "TIA1", "TIAL1", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TJP1", "TK1", "TKT", "TM9SF2", "TM9SF3", "TMED10", "TMED2", "TMED7", "TMEM87A", "TMOD3", "TMPO", "TMX2", "TNPO1", "TNPO2", "TOE1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TP53", "TP53BP1", "TPI1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRAP1", "TRAPPC4", "TRIM21", "TRIM27", "TRIP12", "TRIP13", "TRMT10C", "TRMT11", "TRMT2A", "TRMT6", "TROVE2", "TRUB1", "TSC2", "TSFM", "TSG101", "TSPYL1", "TSTA3", "TTK", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA6", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UBE2V1", "UBE3C", "UBE4A", "UBR4", "UBR5", "UBTF", "UCHL5", "UCK2", "UFL1", "UGDH", "UGGT1", "UHRF1", "UMPS", "UNC119", "UNC119B", "UNG", "UPF2", "UQCC1", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "UROD", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP19", "USP28", "USP33", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP6", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VBP1", "VDAC1", "VDAC2", "VDAC3", "VPS13A", "VPS18", "VPS26A", "VPS29", "VPS33A", "VPS35", "VPS4A", "VPS53", "VRK1", "VRK3", "WARS", "WDHD1", "WDR1", "WDR33", "WDR82", "WIZ", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YME1L1", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H15", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZFR", "ZMPSTE24", "ZMYM4", "ZNF326", "ZNF598", "ZNF622", "ZRANB2", "ZW10", "ZYX"], "leading_proteins": ["ABCB7", "ABCC1", "ABCC4", "ABHD10", "ABHD12", "ACOX1", "ACOX3", "AKAP12", "AKT1", "AKT2", "AP1B1", "AP2A2", "ARF4", "ARHGDIA", "ARL1", "ARL6IP5", "ARPC3", "ATP6", "ATP6V1B2", "ATPAF1", "ATRX", "BAG6", "BAIAP2", "BCAT2", "BZW2", "CALR", "CAP1", "CBFB", "CDK13", "CHKA", "CHMP7", "CKAP2", "CLGN", "CLNS1A", "COA3", "COL4A3BP", "COX4I1", "COX7C", "CPOX", "CYB5B", "CYP20A1", "CYP51A1", "DCTN4", "DENR", "DERL1", "DHX29", "DHX30", "DHX36", "DNAJA3", "DNAJC9", "DOHH", "DPM1", "DYNC1H1", "DYNC1LI2", "ECSIT", "EHD1", "EIF3A", "EIF3F", "EIF4G1", "ELMO2", "ERAP1", "ERMP1", "EXOC4", "FDXR", "FH", "FKBP5", "FKBP7", "FKBP8", "GABARAPL2", "GATAD2A", "GLO1", "GNAI2", "GOT1", "GPT2", "H1F0", "H1FX", "H2AFX", "H2AFY2", "H4C1*", "HIST1H1C", "HIST1H1E", "HMOX2", "HSP90AB1", "ILKAP", "IPO11", "IRF2BPL", "ISCU", "KCTD12", "KDM1A", "KDM1B", "KIF1A", "KIF23", "KIF2A", "KIF2C", "KIF4A", "LAP3", "LETM1", "LRPAP1", "M6PR", "MAP2K2", "MAP3K7", "MAPK14", "MARK2", "MCCC2", "MCTS1", "MECP2", "MED25", "MIA3", "MIPEP", "MPRIP", "MRPL12", "MRPL14", "MRPL17", "MRPL28", "MRPL40", "MRPL45", "MRPL50", "MRPL9", "MRPS10", "MRPS17", "MRPS23", "MRPS28", "MRPS35", "MRPS5", "MRRF", "MSMO1", "MSN", "MTA1", "MTIF2", "NDUFA11", "NDUFA8", "NDUFB11", "NDUFB3", "NECAP1", "NPTN", "NRBP1", "NT5C3A", "NUF2", "OXA1L", "PABPN1", "PAK1IP1", "PARP2", "PCK2", "PCMT1", "PCYOX1", "PDXK", "PFDN5", "PKMYT1", "PLA2G15", "PMPCA", "POLE", "PPIL1", "PPM1F", "PPOX", "PPP3CA", "PRC1", "PRDX2", "PRDX3", "PRDX6", "PRIM1", "PRKAG1", "PRKAR1A", "PSMD14", "PSMG1", "PSMG3", "PUS1", "QRICH1", "RACGAP1", "RANBP9", "RASA1", "RBM34", "RDX", "RPL10A", "RPL12", "RPL22", "RPL23A", "RPL27", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL7", "RPL7A", "RPL9", "RPLP0", "RPLP2", "RPN2", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS18", "RPS19", "RPS2", "RPS3A", "RPS6", "RPS7", "RPS8", "RPSA", "RSU1", "SAP30BP", "SCARB1", "SCO1", "SEPT6", "SEPT9", "SHOC2", "SLC25A21", "SLC35B2", "SNX1", "SNX27", "SOD2", "SRBD1", "SRPRA", "SSBP1", "STAM", "STK4", "STT3B", "SUN1", "SURF4", "SYNGR2", "SYNJ2BP", "TAB1", "TBCB", "TDRKH", "TIMM17A", "TIMM17B", "TMEM87A", "TOMM22", "TPP1", "TRAP1", "TRMT6", "TSTA3", "TUBB2A", "TUBB4A", "TUBB4B", "TUBGCP3", "TXLNA", "TXNL1", "UGGT1", "UNC119", "UNC119B", "UNG", "UQCC1", "UQCRQ", "VPS13A", "VPS26A", "VRK1", "VRK3", "XPO4", "YME1L1", "YTHDC2", "YWHAH", "ZADH2", "ZMPSTE24", "ZMYM4", "ZYX"]} \ No newline at end of file diff --git a/pharos_dto/advanced/idx2term.json b/pharos_dto/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..dd049db59391e9cea38c5d69c1643ad82bc2113e --- /dev/null +++ b/pharos_dto/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Receptor"} \ No newline at end of file diff --git a/pharos_dto/advanced/plot_0.png b/pharos_dto/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..d5906cb08f9ec97b603133cdb5422323a584e7f3 --- /dev/null +++ b/pharos_dto/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f9964ffe9473f04b85ce6b9b2e6852b108eab6e913c584a2a75fb1149a8a1850 +size 206143 diff --git a/pharos_dto/basic/idx2term.json b/pharos_dto/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..e16a3428a740d4c56eb665bb6f661012c9c9b00a --- /dev/null +++ b/pharos_dto/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Receptor", "1": "Histone", "2": "Oxidase", "3": "Transporter", "4": "Metalloprotease", "5": "Kinase", "6": "Protein kinase", "7": "Ribosomal protein", "8": "Microtubule family cytoskeletal protein", "9": "SLC superfamily of solute carriers", "10": "Enzyme modulator", "11": "Protease", "12": "G-protein modulator", "13": "Cysteine protease", "14": "Phosphatase", "15": "Phosphatase modulator", "16": "Phosphatase inhibitor", "17": "Small GTPase"} \ No newline at end of file diff --git a/pharos_dto/basic/plot_0.png b/pharos_dto/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..1df80f2f64cd976cb126c23343b554ec33a4fc25 --- /dev/null +++ b/pharos_dto/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9e782789dad6d94e15f072ac82b8d0d872a2e23a58fefae0b9ecd77fd5a62de5 +size 133286 diff --git a/pharos_dto/basic/plot_1.png b/pharos_dto/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..37a55c833e499e4f3e0395c62c2f6d46598f16c5 --- /dev/null +++ b/pharos_dto/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5716474913e84326edb7d66872155cb6d36f7190ddaf38bd72ab82d4d0cb189c +size 127394 diff --git a/pharos_dto/basic/plot_10.png b/pharos_dto/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..25441cc6c25a845b79e483c0b8224bae9f752e3d --- /dev/null +++ b/pharos_dto/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4cc6bd92a795cc55502a56d5c5fdbcc48811ec0686f2e8f25e560a1df4124226 +size 144101 diff --git a/pharos_dto/basic/plot_11.png b/pharos_dto/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..18a829e56bc804a6d7b4f225f567f9df04a9c6d3 --- /dev/null +++ b/pharos_dto/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7787a4f45f1818c580aa6eee8d258d10a0df8c4def265bbfa437055110582527 +size 137699 diff --git a/pharos_dto/basic/plot_12.png b/pharos_dto/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..a7a537225ba8868264cf85db3b18c3d0543c7b46 --- /dev/null +++ b/pharos_dto/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1b87fbde9e809272f4ef4d00800d36f6d4c949c437d1b7d723f68b34c238b3a6 +size 134639 diff --git a/pharos_dto/basic/plot_13.png b/pharos_dto/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..702e4c980d1466a03ae300f3cea8893d69e77c90 --- /dev/null +++ b/pharos_dto/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:db9e98fe1d75426445688d804de110cfd9b5fbf16b08e7a783095ffa614534d6 +size 142083 diff --git a/pharos_dto/basic/plot_14.png b/pharos_dto/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..d57886f5b35bd84f2c17acecbbc11310f04d129a --- /dev/null +++ b/pharos_dto/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d95b9cd709c94dcda23166268a97b364448bb76c6d8d9f2a75683e3f9b38489d +size 145493 diff --git a/pharos_dto/basic/plot_15.png b/pharos_dto/basic/plot_15.png new file mode 100644 index 0000000000000000000000000000000000000000..6193403cc2608ac13bfb082b09884c89d7780dd9 --- /dev/null +++ b/pharos_dto/basic/plot_15.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:28e1ba87293b61c7218ba7e4a504df65ef3f09aa766c0de6712cc610e27ad559 +size 145748 diff --git a/pharos_dto/basic/plot_16.png b/pharos_dto/basic/plot_16.png new file mode 100644 index 0000000000000000000000000000000000000000..d3b89c3aa272f6ce63b1bf0bef80125d58541188 --- /dev/null +++ b/pharos_dto/basic/plot_16.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:18536c285361a54a9f8f2c95cdc49b592e6599201f7148b142394845a5969fbf +size 143824 diff --git a/pharos_dto/basic/plot_17.png b/pharos_dto/basic/plot_17.png new file mode 100644 index 0000000000000000000000000000000000000000..a7ea5007127f63c9fc7b9320c29abf6638f74c0b --- /dev/null +++ b/pharos_dto/basic/plot_17.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a95ac9a19b7c54df6c020ebdf5962b8249a02c2abd9d31a3a2c50023071b5321 +size 146905 diff --git a/pharos_dto/basic/plot_2.png b/pharos_dto/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..5e4f97357b6274568baa3b4ef71a4282342fbe9b --- /dev/null +++ b/pharos_dto/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4b3a38dbeb443962f9775528a8f7b963ecc57c7aa510e09613433c532182e42c +size 135542 diff --git a/pharos_dto/basic/plot_3.png b/pharos_dto/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..eb76fd576a93552a4b4aad68fa9338d4a30706d2 --- /dev/null +++ b/pharos_dto/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a8f875dd61e69fe691ea4f0072812ff2b8cae38da756af75cffd7a63e98f5667 +size 137264 diff --git a/pharos_dto/basic/plot_4.png b/pharos_dto/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..66020d8c19c152138145ecaf354cf545045085ed --- /dev/null +++ b/pharos_dto/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:99d5ff8d2531697683a87638a3db908cc48f62376b69a79419cf44dbe5bf2417 +size 145520 diff --git a/pharos_dto/basic/plot_5.png b/pharos_dto/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..4547799644123975116b255a93815d355dfe3072 --- /dev/null +++ b/pharos_dto/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b8f2362a23f5f7ae5505797475f6155c0d75eccefaaa5e7742eea9b55b687a80 +size 137915 diff --git a/pharos_dto/basic/plot_6.png b/pharos_dto/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..8708cc17095c4115f26bf49685debeeacbef626f --- /dev/null +++ b/pharos_dto/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:50f24b3db9604863362b9f25dc66e9983463d3ccb7a20a65b144f8e22f3bd33d +size 132942 diff --git a/pharos_dto/basic/plot_7.png b/pharos_dto/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..7560491229be54030f100a53e722cfea25127cea --- /dev/null +++ b/pharos_dto/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a4ee211661a7a0b84fce6b4d7d64d74ff657d7e3a30be7cf83124fa522a7a538 +size 145784 diff --git a/pharos_dto/basic/plot_8.png b/pharos_dto/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..2334ac76ee6e8ee0e5200ef23efa74294d4f4958 --- /dev/null +++ b/pharos_dto/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d0588846873dc53f8903914c943219121259b6167892280f743c9634499627e7 +size 150996 diff --git a/pharos_dto/basic/plot_9.png b/pharos_dto/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..b3a83eb34da0e987dfbb91bea00968ec96efc439 --- /dev/null +++ b/pharos_dto/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5c8753a16f02355ba322584a54bf2316e6300e2b70e1b92112631eecd879649e +size 152865 diff --git a/pharos_dto/consensus.joblib b/pharos_dto/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..3455529971890f58cb4c08f41b6e7ada6c826b63 --- /dev/null +++ b/pharos_dto/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:35a15f5f957a0e4b996ea38d189141387425ae6bb837908287887b2e7be0e4c4 +size 577361 diff --git a/pharos_dto/df_merge.tsv b/pharos_dto/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..5c2d4f0c7b588bf9c47751d107f297ab5037c3d4 --- /dev/null +++ b/pharos_dto/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Receptor 6 25 3.199978231242578 0.0013743796767224 8.25242718446602 27.344660194174757 1.739519175745715 0.1905542238199536 2.855648283399814 4.245230977176689 1.1861053756197322 0.2707159726336181 1.0 0.0134616854761267 5.24179262794909e-05 0.0034833275784904 0.0294712579434189 +Other small molecule kinase 2 6 2.210357964221849 0.0270803287283734 1.6067961165048543 4.87621359223301 0.1050165406566997 0.5224213534548736 1.4584046434589368 0.968793280528811 0.986745169262007 0.3023106065959564 1.0 0.0595353304203936 0.0061398538588971 0.0030929731790992 0.0215291267260604 diff --git a/pharos_dto/metrics.json b/pharos_dto/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..cb90418e0c95f651bea9a6fd45ce81a859b579b9 --- /dev/null +++ b/pharos_dto/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2772, + "annotations_size": 1822, + "title": "Average number of proteins per term", + "value": 3.1289791437980243 +} \ No newline at end of file diff --git a/pharos_dto/paths.json b/pharos_dto/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..0900df50e6b38903a59a1edf898e27c4306575cd --- /dev/null +++ b/pharos_dto/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_dto/fragment/C321/C321_val_log2fc"} \ No newline at end of file diff --git a/pharos_dto/result.tsv b/pharos_dto/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..db0aa06c34df21e833d772e208a5e03091de6755 --- /dev/null +++ b/pharos_dto/result.tsv @@ -0,0 +1,64 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Receptor 0.7668557064765865 3.199978231242578 0.0013743796767224 0.9183931565703876 0.0044242398780713 25 Q9UQB8,A6NIH7,Q9Y639,Q8WTV0,P20645,Q13432 6 +ABCC subfamily 0.9682310469314076 2.570566572058424 0.0101532310306309 0.9999999915891288 0.0196178549325454 2 P33527 1 +AKT family 0.9259927797833928 2.3878488487723786 0.0169473102687207 0.99999999999997 0.0294637397992454 2 P31749 1 +SLC35 family of nucleotide sugar transporters 0.9191335740072196 2.3578702268851455 0.018380117127043 0.999999999999998 0.0314151720501617 2 Q8IXU6 1 +Other small molecule kinase 0.911789428536613 2.210357964221849 0.0270803287283734 1.0 0.0434081701209922 6 O00764,Q16822 2 +VRK family 0.8321299638989156 1.9705248156986828 0.0487782537894947 1.0 0.0703116917756799 2 Q99986 1 +Non-protein kinase 0.5955427445715413 1.819793356294956 0.0687904798663023 1.0 0.0926358125028846 17 O00764,Q16822 2 +STE group 0.806641254172477 1.7967970805578362 0.0723678400228418 1.0 0.0966673053677549 6 Q13043,O95747 2 +ATP-binding cassette transporter family 0.7933670416501055 1.7434496024844044 0.0812551103036209 1.0 0.1064909795323778 6 P33527,O75027 2 +Histone 0.6645426367648052 1.7018185199140312 0.0887893936573853 1.0 0.1139255459463071 11 P10412,P62805,P16403,P16104,Q92522,P07305,Q9P0M6 7 +DNA-directed RNA polymerase 0.6451488967888056 1.6074587265512703 0.1079537763994573 1.0 0.1337129711759424 11 P19388 1 +STE7 family 0.7487364620938604 1.5887552702452388 0.1121156553518822 1.0 0.1375587367347673 2 P36507 1 +Ion channel 0.7323905590846509 1.4957370926744464 0.1347221801931888 1.0 0.1599112783791466 6 Q8NE86 1 +Reductase 0.5376682909061186 1.4451964726046396 0.1484027069269822 1.0 0.1733267512954882 16 Q15392,P14927,Q9UDW1 3 +Oxidase 0.4972483781520896 1.4180432270677474 0.1561781447716481 1.0 0.1803273636083288 21 O43169,P36551,Q15067,O15254,Q15800,O15260 6 +STE20 family 0.8527085891548221 1.4007884543789806 0.1612773422036535 1.0 0.184693474226937 4 O95747 1 +F-type ATPase 0.6578875267656619 1.3773716868073234 0.1683973618995242 1.0 0.1908084535951077 8 P00846 1 +Transporter 0.3157528002273331 1.3526772952731367 0.1761587469593952 1.0 0.1979008975643082 166 O95202,Q9C0E2,Q9NZD2,Q9Y5P4,O43760,P33527,P00846,Q9HD45,Q9NRK6,Q8TAD4,P54105,O75027,Q13596,Q9P253,Q9H2D1,Q9BQT8,Q9Y584,Q96A65,Q9UBX3,P21281,Q10567,Q70HW3,Q15070,P56385,O15439,O95721,O75436,Q8WUX9,Q8TB61,Q8TAG9,Q8IXU6,O00161 32 +SLC25 family of mitochondrial transporters 0.4913557822267376 1.3308263128185367 0.1832461678021872 1.0 0.204204598003416 20 Q9BQT8,Q70HW3,Q9H2D1 3 +F-type and V-type ATPases 0.5159635411726509 1.3197952620997 0.186903383902949 1.0 0.2075185651865771 16 P21281,P00846 2 +Adenylate kinase family 0.689891696750899 1.3160619681829837 0.188153244583527 1.0 0.2082482270888005 2 P00568 1 +Kinase modulator 0.5671357330234759 1.2233698269106936 0.2211900443712622 1.0 0.238890492498186 11 P60983,Q9NQG5,P14635 3 +Serine protease inhibitor 0.6628158844765306 1.1907854679883183 0.2337378151930698 1.0 0.2509548021695775 2 P50454 1 +Lysine-specific demethylase 0.6581227436823066 1.1691402353364688 0.2423471354667163 1.0 0.2594338900237116 2 O60341 1 +Calcium-binding protein 0.4860378558848859 1.1235318825222615 0.2612116677027774 1.0 0.2789728361983941 15 P80303 1 +Mitochondrial di- and tri-carboxylic acid transporter subfamily 0.7544625962242694 1.0407456679756069 0.2979936021132263 1.0 0.3167703285007575 4 Q9BQT8 1 +CK1 group 0.7649893782370276 1.018090956789072 0.3086347325522371 1.0 0.3275087260979477 3 Q99986 1 +Miscellaneous SLC25 mitochondrial transporters 0.6231046931407898 1.0087976310347957 0.313071697436259 1.0 0.3318305018783385 2 Q9Y6C9 1 +Glycosyltransferase 0.4672274955809885 0.997379030369847 0.3185805659152003 1.0 0.337277043054907 14 Q8TCJ2,O60762,Q9NYU2,P04844 4 +Metalloprotease 0.378272766734564 0.989681139379961 0.3223299965384545 1.0 0.3410483470923717 37 O75844,O00487,Q9NZ08,Q96TA2,O00303 5 +Mitochondrial nucleotide transporter subfamily 0.5470643238249242 0.8898687784113626 0.3735363502510744 1.0 0.3943124160819569 8 Q70HW3 1 +Kinase 0.3144017086281423 0.8719061117113764 0.383259599249294 1.0 0.4043422060406564 85 O95747,Q9UHY1,Q7KZI7,Q16822,P36507,Q9BRR6,Q14004,P00568,O00764,O43318,P31749,Q15750,Q16539,P31751,Q99640,Q99986,Q8IV63,Q13043,P35790,P54619 20 +Intracellular chloride channel (clic) family 0.5837545126353743 0.8326905822058367 0.4050192573261819 1.0 0.4268045615085619 2 Q9Y696 1 +Microtubule binding motor protein 0.4819097131031594 0.8069058526949694 0.4197207266293643 1.0 0.4415188933239506 11 O00139,Q02241,Q99661,Q12756 4 +Protein kinase 0.3444617990382211 0.7648950761729889 0.4443340261493951 1.0 0.4663459652328329 50 Q9UHY1,O95747,Q14004,O43318,Q7KZI7,P31749,Q16539,P31751,Q99640,Q8IV63,Q99986,P36507,Q13043,P54619 14 +ABCB subfamily 0.6662684189507014 0.6720103846832789 0.5015770852525818 1.0 0.5234097647939313 3 O75027 1 +Ribosomal protein 0.3007973684785641 0.6705303814975827 0.5025197457113482 1.0 0.5240932894596888 97 P62906,P47914,P18077,Q6P1L8,Q9NTZ6,P52815,P62910,Q9Y3U8,P62899,P62753,P49406,P62424,P62841,Q9NRX2,P32969,P63173,P62263,P62081,P15880,Q96E11,P30050,Q92552,P82673,P62241,P35268,P82675,P62244,P62829,P62269,O00541,Q9BYD2,P39019,P62750,P78316,P08865,P62277,P46781,P46779,P61353,P42766,Q8TDN6,P18124,P26373,Q92979 44 +Microtubule family cytoskeletal protein 0.3316069806566911 0.6418008688492838 0.5210024854479309 1.0 0.5420847225857478 39 P68371,P04350,Q02241,O00139,Q12756,Q99661,O43237,Q9BSJ2,Q96CW5,P60520,O94901,O43663 12 +Heterotrimeric G-protein 0.4879759525694211 0.5774898467744018 0.5636085954884591 1.0 0.5847920620614877 7 P04899 1 +SLC superfamily of solute carriers 0.3249670518174373 0.4983198689835125 0.6182586056969512 1.0 0.637863635096175 35 O95202,Q8TB61,Q8TAD4,Q70HW3,Q9H2D1,Q8IXU6,Q9BQT8 7 +Enzyme modulator 0.2838057840400135 0.4769870231509736 0.6333713623061694 1.0 0.6527164152272854 95 P55036,P63218,P20936,Q9H4M9,Q14141,Q96DV4,Q9H0U9,Q9NQG5,P53367,Q9UI26,Q9H0H5,P46379,P53365,P04899,O14737,P14635 16 +Hsp90 family chaperone 0.5868803853317258 0.4722954870277888 0.6367158911733246 1.0 0.6557921728195576 4 Q12931,P08238 2 +Protein phosphatase 0.4150612180842587 0.4509590923332488 0.6520190326042496 1.0 0.6700387351409717 10 Q9H0C8,P49593 2 +Methyltransferase 0.3611855477920938 0.3341395106955357 0.7382742865485659 1.0 0.7565442913900376 12 P22061 1 +Non-motor microtubule binding protein 0.329877414816432 0.3100587437045589 0.7565162849534357 1.0 0.7734975708109764 15 O94901,O43663,Q96CW5,P60520 4 +Protease 0.2701990297883201 0.2832320637501944 0.7769989509095947 1.0 0.7939944411426144 112 O75844,O00303,Q8TEY7,P22570,O00487,Q14195,Q9Y6M1,Q9NZ08,Q8TCT8,P42785,Q96TA2,Q9Y4P1,Q9Y3P9,Q8N2K0,O14773 15 +Atypical group 0.5085594950799381 0.2297335114190611 0.818298852922493 1.0 0.8338593456514443 3 Q15120 1 +G-protein 0.2874419580187988 0.2053617143544453 0.8372895302802759 1.0 0.8527342225660496 30 P63218,P04899,Q9UI26 3 +G-protein modulator 0.2873716894118714 0.1870382904191046 0.8516306112505432 1.0 0.8668552925689886 21 Q9H4M9,P20936,P53367,Q9H0H5,P53365 5 +PIKK family 0.3935018050541447 0.169206119582552 0.8656345164674062 1.0 0.8805181702586062 2 P42345 1 +Tubulin 0.3559066808906926 0.145837185258275 0.884049920122407 1.0 0.8978478007040277 6 P68371,P04350,Q13885 3 +Membrane trafficking regulatory protein 0.2798246263548374 0.1360030921889758 0.8918188364669277 1.0 0.904225887614214 17 O43760,Q13596 2 +Cysteine protease 0.2545468100810914 0.1167067589879128 0.9070924339844396 1.0 0.918179119288694 39 Q92643,Q8TEY7,P22570,P42574,Q9Y3P9,Q9Y4P1 6 +Transcription factor 0.2636788501985925 0.1017519834539532 0.9189535394023594 1.0 0.929152801770865 29 Q71SY5,O00625,Q9NY61,Q9UHR5 4 +V-type ATPase 0.310013271922931 0.097602014306687 0.9222483249598824 1.0 0.9319669706472024 8 P21281 1 +Phosphatase 0.2582609368657362 0.081980013175351 0.9346626071246172 1.0 0.9439885089695412 27 Q01968,Q9H0R4,Q9BX68,Q9NX62,P49593,O95140 6 +Nucleotide phosphatase 0.300604634253004 0.0711399892578542 0.9432863419522072 1.0 0.9516432530658478 7 Q9BX68,O95140 2 +Transaminase 0.2942822728786711 0.0633197137329518 0.9495119179728913 1.0 0.9568643332669292 7 Q8TD30 1 +Ca2+-ATPases 0.3445287107258922 0.0354381321475211 0.9717303787397392 1.0 0.9770931291742854 3 P98194,P20020 2 +Phosphatase modulator 0.2431259044862518 0.0227604582387259 0.9818413496012692 1.0 0.986171410679996 8 Q15257,Q01105,Q9BTT0,Q9H0U9,Q92688,Q99733,P55209 7 +Phosphatase inhibitor 0.2430379746835383 0.0206737913781034 0.9835058760014852 1.0 0.986755344754794 7 Q01105,Q9BTT0,Q9H0U9,Q92688,Q99733,P55209 6 +Peroxidase 0.2337427745664785 0.0140379478237313 0.9887997060297128 1.0 0.991520673850378 4 P30041,P30048,P32119 3 +Small GTPase 0.2290143568991672 0.0104228669175564 0.9916839059788642 1.0 0.9933194484296264 22 Q14141,O75616,P84095,Q9UHD8,P50570,Q9UI26,O15397 7 diff --git a/pharos_dto/selections.json b/pharos_dto/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..82c533088b37e4e241d8b118b9c6257dedf43aef --- /dev/null +++ b/pharos_dto/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "10 kDa heat shock protein, mitochondrial", "116 kDa U5 small nuclear ribonucleoprotein component", "14-3-3 protein beta/alpha", "14-3-3 protein epsilon", "14-3-3 protein eta", "14-3-3 protein gamma", "14-3-3 protein theta", "14-3-3 protein zeta/delta", "2',3'-cyclic-nucleotide 3'-phosphodiesterase", "2',5'-phosphodiesterase 12", "2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial", "2-hydroxyacyl-CoA lyase 1", "26S proteasome non-ATPase regulatory subunit 1", "26S proteasome non-ATPase regulatory subunit 12", "26S proteasome non-ATPase regulatory subunit 13", "26S proteasome non-ATPase regulatory subunit 14", "26S proteasome non-ATPase regulatory subunit 2", "26S proteasome non-ATPase regulatory subunit 3", "26S proteasome non-ATPase regulatory subunit 4", "26S proteasome non-ATPase regulatory subunit 7", "26S proteasome non-ATPase regulatory subunit 8", "26S proteasome regulatory subunit 10B", "26S proteasome regulatory subunit 4", "26S proteasome regulatory subunit 6A", "26S proteasome regulatory subunit 6B", "26S proteasome regulatory subunit 7", "26S proteasome regulatory subunit 8", "28S ribosomal protein S2, mitochondrial", "28S ribosomal protein S27, mitochondrial", "28S ribosomal protein S29, mitochondrial", "28S ribosomal protein S35, mitochondrial", "28S ribosomal protein S5, mitochondrial", "28S ribosomal protein S7, mitochondrial", "3'(2'),5'-bisphosphate nucleotidase 1", "3'-5' exoribonuclease 1", "3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase", "3-hydroxyacyl-CoA dehydrogenase type-2", "3-hydroxyisobutyrate dehydrogenase, mitochondrial", "3-hydroxyisobutyryl-CoA hydrolase, mitochondrial", "3-ketoacyl-CoA thiolase, mitochondrial", "3-ketoacyl-CoA thiolase, peroxisomal", "3-mercaptopyruvate sulfurtransferase", "39S ribosomal protein L1, mitochondrial", "39S ribosomal protein L11, mitochondrial", "39S ribosomal protein L12, mitochondrial", "39S ribosomal protein L14, mitochondrial", "39S ribosomal protein L17, mitochondrial", "39S ribosomal protein L19, mitochondrial", "39S ribosomal protein L2, mitochondrial", "39S ribosomal protein L21, mitochondrial", "39S ribosomal protein L38, mitochondrial", "39S ribosomal protein L39, mitochondrial", "39S ribosomal protein L44, mitochondrial", "39S ribosomal protein L9, mitochondrial", "4-trimethylaminobutyraldehyde dehydrogenase", "40S ribosomal protein S10", "40S ribosomal protein S11", "40S ribosomal protein S12", "40S ribosomal protein S13", "40S ribosomal protein S14", "40S ribosomal protein S15", "40S ribosomal protein S15a", "40S ribosomal protein S17", "40S ribosomal protein S18", "40S ribosomal protein S19", "40S ribosomal protein S2", "40S ribosomal protein S20", "40S ribosomal protein S21", "40S ribosomal protein S23", "40S ribosomal protein S24", "40S ribosomal protein S26", "40S ribosomal protein S28", "40S ribosomal protein S3", "40S ribosomal protein S3a", "40S ribosomal protein S4, X isoform", "40S ribosomal protein S5", "40S ribosomal protein S6", "40S ribosomal protein S7", "40S ribosomal protein S8", "40S ribosomal protein S9", "40S ribosomal protein SA", "4F2 cell-surface antigen heavy chain", "5'-AMP-activated protein kinase catalytic subunit alpha-1", "5'-AMP-activated protein kinase subunit gamma-1", "5'-nucleotidase domain-containing protein 1", "5'-nucleotidase domain-containing protein 2", "6-phosphogluconate dehydrogenase, decarboxylating", "6-phosphogluconolactonase", "60 kDa SS-A/Ro ribonucleoprotein", "60S ribosomal protein L10", "60S ribosomal protein L10a", "60S ribosomal protein L11", "60S ribosomal protein L12", "60S ribosomal protein L13", "60S ribosomal protein L13a", "60S ribosomal protein L14", "60S ribosomal protein L15", "60S ribosomal protein L18", "60S ribosomal protein L19", "60S ribosomal protein L21", "60S ribosomal protein L22", "60S ribosomal protein L23", "60S ribosomal protein L23a", "60S ribosomal protein L24", "60S ribosomal protein L26", "60S ribosomal protein L27", "60S ribosomal protein L27a", "60S ribosomal protein L28", "60S ribosomal protein L29", "60S ribosomal protein L3", "60S ribosomal protein L30", "60S ribosomal protein L31", "60S ribosomal protein L32", "60S ribosomal protein L35", "60S ribosomal protein L35a", "60S ribosomal protein L36", "60S ribosomal protein L36a", "60S ribosomal protein L37", "60S ribosomal protein L38", "60S ribosomal protein L5", "60S ribosomal protein L6", "60S ribosomal protein L7", "60S ribosomal protein L7-like 1", "60S ribosomal protein L7a", "60S ribosomal protein L8", "60S ribosomal protein L9", "7,8-dihydro-8-oxoguanine triphosphatase", "7-methylguanosine phosphate-specific 5'-nucleotidase", "A-kinase anchor protein 1, mitochondrial", "ABCB subfamily", "ABCC subfamily", "ABCD subfamily of peroxisomal ABC transporters", "ADP-dependent glucokinase", "ADP-sugar pyrophosphatase", "ADP/ATP translocase 1", "ADP/ATP translocase 2", "ADP/ATP translocase 3", "AFG3-like protein 2", "AGC group", "AH receptor-interacting protein", "AK1 subfamily", "AK2 subfamily", "AKT family", "AMPK subfamily", "AP-1 complex subunit beta-1", "AP-1 complex subunit gamma-1", "AP-1 complex subunit mu-1", "AP-2 complex subunit alpha-1", "AP-2 complex subunit alpha-2", "AP-2 complex subunit beta", "AP-2 complex subunit mu", "AP-3 complex subunit beta-1", "AP-3 complex subunit delta-1", "AP-3 complex subunit mu-1", "ATP synthase F(0) complex subunit B1, mitochondrial", "ATP synthase mitochondrial F1 complex assembly factor 1", "ATP synthase subunit a", "ATP synthase subunit alpha, mitochondrial", "ATP synthase subunit beta, mitochondrial", "ATP synthase subunit d, mitochondrial", "ATP synthase subunit e, mitochondrial", "ATP synthase subunit f, mitochondrial", "ATP synthase subunit gamma, mitochondrial", "ATP-binding cassette sub-family B member 10, mitochondrial", "ATP-binding cassette sub-family B member 7, mitochondrial", "ATP-binding cassette sub-family D member 3", "ATP-binding cassette sub-family F member 1", "ATP-binding cassette sub-family F member 2", "ATP-binding cassette sub-family F member 3", "ATP-binding cassette transporter family", "ATP-citrate synthase", "ATP-dependent 6-phosphofructokinase, muscle type", "ATP-dependent 6-phosphofructokinase, platelet type", "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial", "ATP-dependent DNA helicase Q1", "ATP-dependent DNA helicase Q4", "ATP-dependent PFK group I subfamily", "ATP-dependent RNA helicase A", "ATP-dependent RNA helicase DHX29", "ATP-dependent RNA helicase DHX8", "ATP-dependent zinc metalloprotease YME1L1", "ATPase ASNA1", "ATPase family AAA domain-containing protein 3A", "ATPase family AAA domain-containing protein 3B", "ATPase inhibitor, mitochondrial", "Acetolactate synthase-like protein", "Acetyl-CoA acetyltransferase, cytosolic", "Acetyl-CoA acetyltransferase, mitochondrial", "Acetyltransferase", "Acid ceramidase", "Acidic leucine-rich nuclear phosphoprotein 32 family member A", "Acidic leucine-rich nuclear phosphoprotein 32 family member B", "Acidic leucine-rich nuclear phosphoprotein 32 family member E", "Aconitate hydratase, mitochondrial", "Actin and actin related protein", "Actin binding motor protein", "Actin family cytoskeletal protein", "Actin-like protein 6A", "Actin-related protein 10", "Actin-related protein 2", "Actin-related protein 2/3 complex subunit 1A", "Actin-related protein 2/3 complex subunit 1B", "Actin-related protein 2/3 complex subunit 3", "Actin-related protein 2/3 complex subunit 4", "Actin-related protein 2/3 complex subunit 5", "Actin-related protein 3", "Acyl-CoA dehydrogenase family member 11", "Acyl-CoA dehydrogenase family member 9, mitochondrial", "Acyl-coenzyme A thioesterase 9, mitochondrial", "Acylamino-acid-releasing enzyme", "Acylpyruvase FAHD1, mitochondrial", "Acyltransferase", "Adenosine 3'-phospho 5'-phosphosulfate transporter 1", "Adenosine deaminase", "Adenosine kinase", "Adenosylhomocysteinase", "Adenylate kinase 2, mitochondrial", "Adenylate kinase 4, mitochondrial", "Adenylate kinase family", "Adenylate kinase isoenzyme 1", "Adenylate kinase isoenzyme 6", "Adenylosuccinate lyase", "Adenylosuccinate synthetase isozyme 2", "Adenylyl cyclase-associated protein 1", "Afadin", "Aflatoxin B1 aldehyde reductase member 2", "Alanine aminotransferase 2", "Alanine--tRNA ligase, cytoplasmic", "Alanine--tRNA ligase, mitochondrial", "Alanine/serine/cysteine transporter subfamily", "Alanyl-tRNA editing protein Aarsd1", "Alcohol dehydrogenase [NADP(+)]", "Alcohol dehydrogenase class-3", "Aldehyde dehydrogenase X, mitochondrial", "Aldehyde dehydrogenase, mitochondrial", "Aldose 1-epimerase", "Aldose reductase", "Alpha-adducin", "Alpha-aminoadipic semialdehyde dehydrogenase", "Alpha-centractin", "Alpha-enolase", "Alpha-soluble NSF attachment protein", "Alpha-taxilin", "Amidophosphoribosyltransferase", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 1", "Aminoacyl-tRNA synthetase", "Ancient ubiquitous protein 1", "Anion channel tweety (tweety) family", "Annexin", "Antibacterial response protein", "Apolipoprotein", "Apolipoprotein L2", "Apoptosis regulator BAX", "Apoptosis-inducing factor 1, mitochondrial", "Arfaptin-1", "Arfaptin-2", "Arsenite methyltransferase", "Asparagine synthetase [glutamine-hydrolyzing]", "Asparagine--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, mitochondrial", "Aspartic protease", "Ataxin-2-like protein", "Atlastin-2", "Atp-dependent 6-phosphofructokinase, liver type", "Atypical SLC22B subfamily", "Atypical group", "B-cell receptor-associated protein 31", "BET1 homolog", "BTB/POZ domain-containing protein KCTD12", "Basic leucine zipper and W2 domain-containing protein 1", "Basic leucine zipper and W2 domain-containing protein 2", "Bcl-2 homologous antagonist/killer", "Bcl-2-associated transcription factor 1", "Beta-galactosidase", "Beta-hexosaminidase subunit alpha", "Beta-hexosaminidase subunit beta", "Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1", "Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase", "Bifunctional coenzyme A synthase", "Bifunctional epoxide hydrolase 2", "Bifunctional glutamate/proline--tRNA ligase", "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial", "Bifunctional purine biosynthesis protein PURH", "Biliverdin reductase A", "Biotin--protein ligase", "Bleomycin hydrolase", "Brain-specific angiogenesis inhibitor 1-associated protein 2", "Branched-chain-amino-acid aminotransferase, mitochondrial", "Bromodomain", "Bromodomain-containing protein 2", "C-1-tetrahydrofolate synthase, cytoplasmic", "C-Jun-amino-terminal kinase-interacting protein 4", "C-terminal-binding protein 1", "C-terminal-binding protein 2", "C2H2 zinc finger transcription factor", "CAAX prenyl protease 1 homolog", "CAD protein", "CAMK group", "CAMKL family", "CASK family", "CCAAT/enhancer-binding protein zeta", "CCK4 family", "CCR4-NOT transcription complex subunit 1", "CCR4-NOT transcription complex subunit 7", "CD2 antigen cytoplasmic tail-binding protein 2", "CD276 antigen", "CDK family", "CDK1 subfamily", "CDK4 subfamily", "CDKN2A-interacting protein", "CK1 family", "CK1 group", "CK2 family", "CLIP-associating protein 2", "CMGC group", "COP9 signalosome complex subunit 3", "COP9 signalosome complex subunit 5", "COP9 signalosome complex subunit 6", "COP9 signalosome complex subunit 8", "CRK7 subfamily", "CSK family", "CTP synthase 1", "CTP synthase 2", "Ca2+-ATPases", "Cadherin", "Calcium homeostasis endoplasmic reticulum protein", "Calcium uniporter protein, mitochondrial", "Calcium uptake protein 1, mitochondrial", "Calcium uptake protein 2, mitochondrial", "Calcium-binding mitochondrial carrier protein Aralar1", "Calcium-binding mitochondrial carrier protein Aralar2", "Calcium-binding mitochondrial carrier protein SCaMC-1", "Calcium-binding protein", "Calcium-binding protein 39", "Calcium-regulated heat-stable protein 1", "Calcium-transporting ATPase type 2C member 1", "Calcyclin-binding protein", "Calmegin", "Calmodulin", "Calnexin", "Calpain-1 catalytic subunit", "Calponin-2", "Calponin-3", "Calreticulin", "Calumenin", "Camp-dependent protein kinase catalytic subunit alpha", "Cancer-related nucleoside-triphosphatase", "Caprin-1", "Carbohydrate kinase", "Carbohydrate sulfotransferase 14", "Carnitine O-palmitoyltransferase 2, mitochondrial", "Cartilage-associated protein", "Casein kinase II subunit alpha'", "Casein kinase i isoform alpha", "Casein kinase ii subunit beta", "Caspase-2", "Caspase-3", "Caspase-6", "Catechol O-methyltransferase", "Catenin alpha-1", "Catenin delta-1", "Cathepsin B", "Cation-dependent mannose-6-phosphate receptor", "Cation-independent mannose-6-phosphate receptor", "Cell adhesion", "Cell cycle and apoptosis regulator protein 2", "Cell division control protein 42 homolog", "Cell division control protein 45 homolog", "Cell division cycle and apoptosis regulator protein 1", "Cell-cell junction", "Cellular structure", "Cellular tumor antigen p53", "Centromere/kinetochore protein zw10 homolog", "Centrosomal protein of 170 kDa", "Chaperone", "Chaperonin", "Charged multivesicular body protein 5", "Charged multivesicular body protein 7", "Chitobiosyldiphosphodolichol beta-mannosyltransferase", "Chloride channel family", "Chloride intracellular channel protein 1", "Chloride intracellular channel protein 4", "Choline kinase alpha", "Choline/ethanolamine kinase family", "Chromatin accessibility complex protein 1", "Chromatin assembly factor 1 subunit A", "Chromatin assembly factor 1 subunit B", "Chromatin/chromatin-binding protein", "Chromobox protein homolog 1", "Chromobox protein homolog 3", "Chromobox protein homolog 5", "Chromodomain", "Chromosome-associated kinesin KIF4A", "Cilia- and flagella-associated protein 20", "Citrate synthase, mitochondrial", "ClC-3/CLCN3 subfamily", "ClC-7/CLCN7 subfamily", "Clathrin heavy chain 1", "Clathrin light chain A", "Cleavage and polyadenylation specificity factor subunit 1", "Cleavage and polyadenylation specificity factor subunit 3", "Cleavage and polyadenylation specificity factor subunit 5", "Cleavage and polyadenylation specificity factor subunit 6", "Cleavage and polyadenylation specificity factor subunit 7", "Cleavage stimulation factor subunit 2", "Cleavage stimulation factor subunit 3", "Cleft lip and palate transmembrane protein 1", "Cleft lip and palate transmembrane protein 1-like protein", "Clustered mitochondria protein homolog", "Coactosin-like protein", "Coatomer subunit alpha", "Coatomer subunit beta", "Coatomer subunit beta'", "Coatomer subunit delta", "Coatomer subunit epsilon", "Coatomer subunit gamma-1", "Coatomer subunit gamma-2", "Coatomer subunit zeta-1", "Cohesin subunit SA-2", "Coilin", "Cold-inducible RNA-binding protein", "Collagen type IV alpha-3-binding protein", "Condensin complex subunit 1", "Condensin-2 complex subunit D3", "Copper-transporting ATPase 2", "Core histone macro-H2A.1", "Core histone macro-H2A.2", "Coronin-1C", "Creatine kinase B-type", "Creatine kinase U-type, mitochondrial", "Crooked neck-like protein 1", "Cu+-ATPases", "Cullin-1", "Cullin-2", "Cullin-4B", "Cullin-5", "Cullin-associated NEDD8-dissociated protein 1", "Cyclase", "Cyclin-dependent kinase 1", "Cyclin-dependent kinase 13", "Cyclin-dependent kinase 2", "Cyclin-dependent kinase 4", "Cyclin-dependent kinase 6", "Cyclin-g-associated kinase", "Cystatin-B", "Cysteine and histidine-rich domain-containing protein 1", "Cysteine desulfurase, mitochondrial", "Cysteine protease", "Cysteine protease ATG4B", "Cysteine protease inhibitor", "Cysteine--tRNA ligase, cytoplasmic", "Cytochrome b-c1 complex subunit 1, mitochondrial", "Cytochrome b-c1 complex subunit 2, mitochondrial", "Cytochrome b-c1 complex subunit 7", "Cytochrome b-c1 complex subunit 9", "Cytochrome b5 type B", "Cytochrome c oxidase subunit 2", "Cytochrome c oxidase subunit 5A, mitochondrial", "Cytochrome c oxidase subunit 5B, mitochondrial", "Cytochrome c oxidase subunit 7A2, mitochondrial", "Cytochrome c oxidase subunit 7C, mitochondrial", "Cytochrome c oxidase subunit NDUFA4", "Cytochrome c-type heme lyase", "Cytokine", "Cytoplasmic FMR1-interacting protein 1", "Cytoplasmic dynein 1 heavy chain 1", "Cytoplasmic dynein 1 intermediate chain 2", "Cytoplasmic dynein 1 light intermediate chain 1", "Cytoplasmic dynein 1 light intermediate chain 2", "Cytoskeleton-associated protein 5", "Cytosol aminopeptidase", "Cytosolic 5'-nucleotidase 3A", "Cytosolic acyl coenzyme A thioester hydrolase", "Cytosolic non-specific dipeptidase", "Cytosolic purine 5'-nucleotidase", "D-3-phosphoglycerate dehydrogenase", "DDB1- and CUL4-associated factor 13", "DMPK family", "DNA (cytosine-5)-methyltransferase 1", "DNA binding protein", "DNA damage-binding protein 1", "DNA glycosylase", "DNA helicase", "DNA ligase", "DNA ligase 1", "DNA ligase 3", "DNA methyltransferase", "DNA mismatch repair protein Msh2", "DNA mismatch repair protein Msh3", "DNA mismatch repair protein Msh6", "DNA polymerase alpha subunit B", "DNA polymerase epsilon subunit 4", "DNA polymerase processivity factor", "DNA primase small subunit", "DNA replication complex GINS protein PSF1", "DNA replication complex GINS protein PSF2", "DNA replication licensing factor MCM2", "DNA replication licensing factor MCM3", "DNA replication licensing factor MCM4", "DNA replication licensing factor MCM5", "DNA replication licensing factor MCM6", "DNA replication licensing factor MCM7", "DNA topoisomerase", "DNA topoisomerase 1", "DNA-3-methyladenine glycosylase", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "DNA-directed RNA polymerase I subunit RPA1", "DNA-directed RNA polymerase I subunit RPA2", "DNA-directed RNA polymerase I subunit RPA43", "DNA-directed RNA polymerase II subunit RPB1", "DNA-directed RNA polymerase II subunit RPB2", "DNA-directed RNA polymerase II subunit RPB7", "DNA-directed RNA polymerase III subunit RPC1", "DNA-directed RNA polymerase, mitochondrial", "DNA-directed RNA polymerases I and III subunit RPAC1", "DNA-directed RNA polymerases I, II, and III subunit RPABC1", "DNA-directed RNA polymerases I, II, and III subunit RPABC5", "DNAPK subfamily", "DYRK family", "Damaged DNA-binding protein", "Deacetylase", "Deaminase", "Death-inducer obliterator 1", "Decarboxylase", "Dehydratase", "Dehydrogenase", "Delta(24)-sterol reductase", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial", "Delta-1-pyrroline-5-carboxylate synthase", "Density-regulated protein", "Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial", "Derlin-1", "Derlin-2", "Desmoglein-2", "Desmoplakin", "Digestive organ expansion factor homolog", "Dihydrofolate reductase", "Dihydrolipoyl dehydrogenase, mitochondrial", "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial", "Dihydropteridine reductase", "Dihydropyrimidinase-related protein 2", "Dihydropyrimidinase-related protein 3", "Dipeptidyl peptidase 1", "Dipeptidyl peptidase 3", "Dipeptidyl peptidase 9", "Dna-dependent protein kinase catalytic subunit", "Dolichol-phosphate mannosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B", "Double-stranded RNA-specific adenosine deaminase", "Drebrin", "Drebrin-like protein", "Dual specificity mitogen-activated protein kinase kinase 1", "Dual specificity mitogen-activated protein kinase kinase 2", "Dual specificity protein kinase ttk", "Dynactin subunit 1", "Dynactin subunit 2", "Dynamin-1", "Dynamin-1-like protein", "Dynamin-2", "Dynamin-like 120 kDa protein, mitochondrial", "Dynein light chain 1, cytoplasmic", "Dystonin", "E3 SUMO-protein ligase RanBP2", "E3 ubiquitin-protein ligase ARIH1", "E3 ubiquitin-protein ligase HUWE1", "E3 ubiquitin-protein ligase Itchy homolog", "E3 ubiquitin-protein ligase NEDD4", "E3 ubiquitin-protein ligase RBBP6", "E3 ubiquitin-protein ligase RNF14", "E3 ubiquitin-protein ligase ZNF598", "E3 ubiquitin-protein ligase listerin", "EH domain-containing protein 1", "ELKS/Rab6-interacting/CAST family member 1", "ELMO domain-containing protein 2", "ER lumen protein-retaining receptor 1", "ER membrane protein complex subunit 2", "ERK subfamily", "ERO1-like protein alpha", "Electron transfer flavoprotein subunit alpha, mitochondrial", "Electron transfer flavoprotein subunit beta", "Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial", "Elongation factor 1-alpha 2", "Elongation factor 1-beta", "Elongation factor 1-delta", "Elongation factor 2", "Elongation factor Ts, mitochondrial", "Elongation factor Tu, mitochondrial", "Elongation factor-like GTPase 1", "Elongator complex protein 1", "Elongator complex protein 3", "Elongin-B", "Elongin-C", "Endodeoxyribonuclease", "Endoplasmic reticulum aminopeptidase 1", "Endoplasmic reticulum aminopeptidase 2", "Endoplasmic reticulum metallopeptidase 1", "Endoplasmic reticulum resident protein 29", "Endoplasmin", "Endoribonuclease", "Endoribonuclease Dicer", "Endothelin-converting enzyme 1", "Engulfment and cell motility protein 2", "Enhancer of mRNA-decapping protein 4", "Enhancer of rudimentary homolog", "Enolase-phosphatase E1", "Enoyl-CoA delta isomerase 1, mitochondrial", "Enoyl-CoA delta isomerase 2, mitochondrial", "Enoyl-CoA hydratase, mitochondrial", "Enzyme", "Enzyme modulator", "Epigenetic regulator", "Epimerase family protein SDR39U1", "Epimerase/racemase", "Epiplakin", "Equilibrative nucleoside transporter 1", "Eraser", "Esterase", "Ethylmalonyl-CoA decarboxylase", "Eukaryotic peptide chain release factor GTP-binding subunit ERF3A", "Eukaryotic peptide chain release factor subunit 1", "Eukaryotic translation initiation factor 2 subunit 1", "Eukaryotic translation initiation factor 2 subunit 2", "Eukaryotic translation initiation factor 2A", "Eukaryotic translation initiation factor 2D", "Eukaryotic translation initiation factor 3 subunit A", "Eukaryotic translation initiation factor 3 subunit B", "Eukaryotic translation initiation factor 3 subunit D", "Eukaryotic translation initiation factor 3 subunit E", "Eukaryotic translation initiation factor 3 subunit F", "Eukaryotic translation initiation factor 3 subunit H", "Eukaryotic translation initiation factor 3 subunit I", "Eukaryotic translation initiation factor 3 subunit J", "Eukaryotic translation initiation factor 3 subunit L", "Eukaryotic translation initiation factor 4 gamma 1", "Eukaryotic translation initiation factor 4 gamma 2", "Eukaryotic translation initiation factor 4 gamma 3", "Eukaryotic translation initiation factor 4B", "Eukaryotic translation initiation factor 4E", "Eukaryotic translation initiation factor 4H", "Eukaryotic translation initiation factor 5", "Eukaryotic translation initiation factor 5A-1", "Eukaryotic translation initiation factor 5B", "Eukaryotic translation initiation factor 6", "Exocyst complex component 4", "Exocyst complex component 5", "Exocyst complex component 6", "Exocyst complex component 7", "Exodeoxyribonuclease", "Exonuclease 1", "Exoribonuclease", "Exosome complex component MTR3", "Exosome complex component RRP4", "Exosome complex component RRP40", "Exosome complex component RRP41", "Exosome complex component RRP42", "Exosome complex component RRP43", "Exosome complex component RRP45", "Exosome complex component RRP46", "Exosome complex exonuclease RRP44", "Exportin-1", "Exportin-2", "Exportin-4", "Exportin-5", "Exportin-7", "Exportin-T", "Extracellular matrix glycoprotein", "Extracellular structure", "Ezrin", "F-actin-capping protein subunit alpha-1", "F-actin-capping protein subunit beta", "F-type ATPase", "F-type and V-type ATPases", "FACT complex subunit SPT16", "FAD-dependent oxidoreductase domain-containing protein 1", "FRAP subfamily", "FRAY subfamily", "Far upstream element-binding protein 1", "Far upstream element-binding protein 2", "Far upstream element-binding protein 3", "Farnesyl pyrophosphate synthase", "Fascin", "Fatty acid synthase", "Ferrochelatase, mitochondrial", "Flap endonuclease 1", "Flavin reductase (NADPH)", "Folate transporter 1", "Forkhead box protein C1", "Fragile X mental retardation syndrome-related protein 1", "Fragile X mental retardation syndrome-related protein 2", "Fumarate hydratase, mitochondrial", "G patch domain-containing protein 4", "G-patch domain and KOW motifs-containing protein", "G-protein", "G-protein coupled receptor", "G-protein modulator", "G-rich sequence factor 1", "G2/mitotic-specific cyclin-B1", "GC-rich sequence DNA-binding factor 2", "GDP-L-fucose synthase", "GHMP kinase family", "GMP synthase [glutamine-hydrolyzing]", "GPI-anchor transamidase", "GTP-binding nuclear protein Ran", "GTP-binding protein 1", "GTPase Era, mitochondrial", "GTPase-activating protein and VPS9 domain-containing protein 1", "Galactokinase", "Galactosidase", "Galectin-3", "Gamma-aminobutyric acid receptor-associated protein-like 2", "Gamma-glutamyl hydrolase", "Gamma-taxilin", "Gamma-tubulin complex component 2", "Gamma-tubulin complex component 3", "Ganglioside GM2 activator", "General transcription factor 3C polypeptide 3", "General transcription factor 3C polypeptide 5", "General vesicular transport factor p115", "Geranylgeranyl transferase type-2 subunit alpha", "Glia maturation factor beta", "Glucosamine-6-phosphate isomerase 1", "Glucose-6-phosphate 1-dehydrogenase", "Glucose-6-phosphate isomerase", "Glucosidase", "Glucosidase 2 subunit beta", "Glutamate dehydrogenase 1, mitochondrial", "Glutamate--cysteine ligase regulatory subunit", "Glutaminase kidney isoform, mitochondrial", "Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1", "Glutamine--tRNA ligase", "Glutamine-rich protein 1", "Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial", "Glutaredoxin-3", "Glutaredoxin-related protein 5, mitochondrial", "Glutathione reductase, mitochondrial", "Glutathione synthetase", "Glyceraldehyde-3-phosphate dehydrogenase", "Glycerol-3-phosphate dehydrogenase, mitochondrial", "Glycerol-3-phosphate phosphatase", "Glycine dehydrogenase (decarboxylating), mitochondrial", "Glycine--tRNA ligase", "Glycogen debranching enzyme", "Glycogen phosphorylase, brain form", "Glycogen phosphorylase, liver form", "Glycogenin-1", "Glycolipid transfer protein", "Glycosidase", "Glycosylase", "Glycosyltransferase", "Glycylpeptide N-tetradecanoyltransferase 1", "Glyoxylate reductase/hydroxypyruvate reductase", "Group XV phospholipase A2", "Growth factor", "GrpE protein homolog 1, mitochondrial", "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12", "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5", "Guanine nucleotide-binding protein G(i) subunit alpha-1", "Guanine nucleotide-binding protein G(i) subunit alpha-2", "Guanine nucleotide-binding protein G(k) subunit alpha", "Guanine nucleotide-binding protein subunit alpha-13", "Guanyl-nucleotide exchange factor", "H(+)/Cl(-) exchange transporter 3", "H(+)/Cl(-) exchange transporter 7", "H/ACA ribonucleoprotein complex subunit 1", "H/ACA ribonucleoprotein complex subunit 2", "HBS1-like protein", "HDAC class I", "HDAC class III", "HEAT repeat-containing protein 1", "HIV Tat-specific factor 1", "Haloacid dehalogenase-like hydrolase domain-containing 5", "Haloacid dehalogenase-like hydrolase domain-containing protein 2", "Heat shock protein 75 kDa, mitochondrial", "Heat shock protein HSP 90-alpha", "Heat shock protein HSP 90-beta", "Helicase", "Helix-turn-helix transcription factor", "Hepatoma-derived growth factor", "Hepatoma-derived growth factor-related protein 2", "Heterogeneous nuclear ribonucleoprotein F", "Heterogeneous nuclear ribonucleoprotein H", "Heterogeneous nuclear ribonucleoprotein H2", "Heterogeneous nuclear ribonucleoprotein H3", "Heterogeneous nuclear ribonucleoprotein K", "Heterogeneous nuclear ribonucleoprotein M", "Heterogeneous nuclear ribonucleoprotein Q", "Heterogeneous nuclear ribonucleoprotein R", "Heterotrimeric G-protein", "Hexokinase family", "Hexokinase-1", "Hexokinase-2", "High mobility group protein B1", "High mobility group protein B2", "High mobility group protein B3", "High mobility group protein HMG-I/HMG-Y", "Histidine triad nucleotide-binding protein 2, mitochondrial", "Histone", "Histone H1.0", "Histone H1.2", "Histone H1.3", "Histone H1.4", "Histone H1x", "Histone H2AX", "Histone H4", "Histone acetyltransferase KAT7", "Histone acetyltransferase type B catalytic subunit", "Histone deacetylase", "Histone deacetylase 1", "Histone deacetylase 2", "Histone deacetylase complex subunit SAP18", "Histone-arginine methyltransferase CARM1", "Histone-lysine N-methyltransferase EHMT1", "Histone-lysine N-methyltransferase EHMT2", "Histone-lysine N-methyltransferase NSD2", "Histone-lysine N-methyltransferase SETD7", "Histone-lysine N-methyltransferase SMYD3", "Hormone", "Hsp90 co-chaperone Cdc37", "Hsp90 family chaperone", "Hydrolase", "Hydroxylase", "Hydroxymethylglutaryl-CoA lyase, mitochondrial", "Hypoxanthine-guanine phosphoribosyltransferase", "IKK family", "INSR family", "ITPK1 family", "Immune response", "Immunoglobulin fold transcription factor", "Immunoglobulin-binding protein 1", "Importin subunit alpha-1", "Importin subunit alpha-4", "Importin subunit alpha-5", "Importin subunit alpha-7", "Importin subunit beta-1", "Importin-11", "Importin-4", "Importin-5", "Importin-7", "Importin-8", "Importin-9", "Inactive serine/threonine-protein kinase vrk3", "Inactive tyrosine-protein kinase 7", "Inhibitor of nuclear factor kappa-b kinase subunit alpha", "Inorganic pyrophosphatase", "Inorganic pyrophosphatase 2, mitochondrial", "Inosine triphosphate pyrophosphatase", "Inosine-5'-monophosphate dehydrogenase 2", "Inositol monophosphatase 3", "Inositol polyphosphate 5-phosphatase OCRL-1", "Inositol-tetrakisphosphate 1-kinase", "Insulin-degrading enzyme", "Insulin-like growth factor 1 receptor", "Insulin-like growth factor 2 mRNA-binding protein 1", "Insulin-like growth factor 2 mRNA-binding protein 2", "Insulin-like growth factor 2 mRNA-binding protein 3", "Integrin beta-1", "Integrin-linked kinase-associated serine/threonine phosphatase 2C", "Interferon-induced, double-stranded rna-activated protein kinase", "Interferon-inducible double-stranded rna-dependent protein kinase activator a", "Interleukin enhancer-binding factor 3", "Intermediate filament", "Intermediate filament binding protein", "Intracellular calcium-sensing protein", "Intracellular chloride channel (clic) family", "Ion channel", "Isoaspartyl peptidase/L-asparaginase", "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial", "Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial", "Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial", "Isoleucine--tRNA ligase, cytoplasmic", "Isoleucine--tRNA ligase, mitochondrial", "Isomerase", "Isopentenyl-diphosphate Delta-isomerase 1", "Isovaleryl-CoA dehydrogenase, mitochondrial", "Jumonji domain-containing", "KH domain-containing, RNA-binding, signal transduction-associated protein 1", "KRAB box transcription factor", "KRR1 small subunit processome component homolog", "Ketosamine-3-kinase", "Kinase", "Kinase activator", "Kinase inhibitor", "Kinase modulator", "Kinesin-1 heavy chain", "Kinesin-like protein KIF11", "Kinesin-like protein KIF1A", "Kinesin-like protein KIF20A", "Kinesin-like protein KIF22", "Kinesin-like protein KIF23", "Kinesin-like protein KIF2A", "Kinesin-like protein KIF2C", "Kinesin-like protein KIF3A", "Kinetochore protein Nuf2", "Kynurenine--oxoglutarate transaminase 3", "L-2-hydroxyglutarate dehydrogenase, mitochondrial", "L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase", "L-lactate dehydrogenase A chain", "L-lactate dehydrogenase B chain", "LIM domain and actin-binding protein 1", "LU7TM family", "La-related protein 1", "La-related protein 4", "La-related protein 4B", "La-related protein 7", "Lamin-B receptor", "Lamina-associated polypeptide 2, isoform alpha", "Lanosterol 14-alpha demethylase", "Large proline-rich protein BAG6", "Lathosterol oxidase", "Lethal(2) giant larvae protein homolog 1", "Leucine-rich repeat and WD repeat-containing protein 1", "Leucine-rich repeat-containing protein 47", "Leucyl-cystinyl aminopeptidase", "Ligase", "Lipase", "Lipid kinase", "Lon protease homolog, mitochondrial", "Long-chain fatty acid transport protein 4", "Long-chain-fatty-acid--CoA ligase 1", "Long-chain-fatty-acid--CoA ligase 3", "Long-chain-fatty-acid--CoA ligase 4", "Long-chain-fatty-acid--CoA ligase 6", "Lupus La protein", "Lyase", "Lymphokine-activated killer t-cell-originated protein kinase", "Lysine demethylase", "Lysine--tRNA ligase", "Lysine-specific demethylase", "Lysine-specific demethylase 3B", "Lysine-specific histone demethylase 1A", "Lysine-specific histone demethylase 1B", "Lysophosphatidic acid phosphatase type 6", "Lysophosphatidylcholine acyltransferase 1", "Lysosomal Pro-X carboxypeptidase", "Lysosomal acid lipase/cholesteryl ester hydrolase", "Lysosomal acid phosphatase", "Lysosomal alpha-glucosidase", "Lysosomal protective protein", "Lysosomal thioesterase PPT2", "Lysosome membrane protein 2", "Lysosome-associated membrane glycoprotein 1", "MAGUK p55 subfamily member 2", "MAGUK p55 subfamily member 6", "MAPK family", "MARK subfamily", "MCU family", "MLK family", "MMS19 nucleotide excision repair protein homolog", "MST subfamily", "Magnesium transporter NIPA2", "Major histocompatibility complex antigen", "Malate dehydrogenase, cytoplasmic", "Malate dehydrogenase, mitochondrial", "Malignant T-cell-amplified sequence 1", "Mannose-6-phosphate isomerase", "Mediator of RNA polymerase II transcription subunit 25", "Medium-chain specific acyl-CoA dehydrogenase, mitochondrial", "Melanoma-associated antigen D2", "Membrane trafficking regulatory protein", "Membrane-associated progesterone receptor component 1", "Membrane-associated progesterone receptor component 2", "Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase", "Metalloprotease", "Metastasis-associated protein MTA1", "Metastasis-associated protein MTA2", "Methyl-CpG-binding domain", "Methyl-CpG-binding protein 2", "Methyl-lysine/arginine binding protein", "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial", "Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial", "Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial", "Methylmalonyl-CoA mutase, mitochondrial", "Methylosome subunit pICln", "Methylsterol monooxygenase 1", "Methyltransferase", "Mevalonate kinase", "Mevalonate kinase subfamily", "Microsomal glutathione S-transferase 2", "Microsomal glutathione S-transferase 3", "Microtubule binding motor protein", "Microtubule family cytoskeletal protein", "Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5", "Microtubule-associated protein 1B", "Microtubule-associated protein 1S", "Microtubule-associated protein RP/EB family member 1", "Microtubule-associated protein RP/EB family member 2", "Minor histocompatibility antigen H13", "Miscellaneous SLC25 mitochondrial transporters", "Mitochondrial 2-oxodicarboxylate carrier", "Mitochondrial 2-oxoglutarate/malate carrier protein", "Mitochondrial Rho GTPase 1", "Mitochondrial Rho GTPase 2", "Mitochondrial amino acid transporter subfamily", "Mitochondrial carnitine/acylcarnitine carrier protein", "Mitochondrial carrier homolog 1", "Mitochondrial carrier homolog 2", "Mitochondrial di- and tri-carboxylic acid transporter subfamily", "Mitochondrial dicarboxylate carrier", "Mitochondrial folate transporter/carrier", "Mitochondrial glutamate carrier 1", "Mitochondrial import inner membrane translocase subunit Tim22", "Mitochondrial import receptor subunit TOM20 homolog", "Mitochondrial import receptor subunit TOM40 homolog", "Mitochondrial inner membrane protein OXA1L", "Mitochondrial intermediate peptidase", "Mitochondrial nucleotide transporter subfamily", "Mitochondrial ornithine transporter 1", "Mitochondrial phosphate transporters", "Mitochondrial proton/calcium exchanger protein", "Mitochondrial thiamine pyrophosphate carrier", "Mitochondrial-processing peptidase subunit alpha", "Mitochondrial-processing peptidase subunit beta", "Mitofusin-2", "Mitogen-activated protein kinase 1", "Mitogen-activated protein kinase 14", "Mitogen-activated protein kinase 3", "Mitogen-activated protein kinase kinase kinase 7", "Mitotic checkpoint protein BUB3", "Moesin", "Molybdate-anion transporter", "Monoacylglycerol lipase ABHD12", "Monoacylglycerol lipase ABHD6", "Monocarboxylate transporter 1", "Monofunctional C1-tetrahydrofolate synthase, mitochondrial", "Mortality factor 4-like protein 1", "Mortality factor 4-like protein 2", "Mpv17-like protein 2", "Multidrug resistance protein 1", "Multidrug resistance-associated protein 1", "Multidrug resistance-associated protein 4", "Multifunctional protein ADE2", "Mutase", "Myb-binding protein 1A", "Myelin expression factor 2", "Myosin light polypeptide 6", "Myosin phosphatase Rho-interacting protein", "Myotubularin-related protein 6", "N-acetyl-D-glucosamine kinase", "N-acetylglucosamine-6-sulfatase", "N-acylneuraminate cytidylyltransferase", "N-alpha-acetyltransferase 10", "N-alpha-acetyltransferase 15, NatA auxiliary subunit", "N-alpha-acetyltransferase 25, NatB auxiliary subunit", "N-alpha-acetyltransferase 35, NatC auxiliary subunit", "N-alpha-acetyltransferase 50", "N-terminal Xaa-Pro-Lys N-methyltransferase 1", "NAD kinase 2, mitochondrial", "NAD(P) transhydrogenase, mitochondrial", "NAD-dependent malic enzyme, mitochondrial", "NAD-dependent protein deacetylase sirtuin-1", "NAD-dependent protein deacetylase sirtuin-2", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial", "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial", "NADP-dependent malic enzyme", "NADPH:adrenodoxin oxidoreductase, mitochondrial", "NAK family", "NEDD8-activating enzyme E1 catalytic subunit", "NEDD8-activating enzyme E1 regulatory subunit", "NEK family", "NF-kappa-B-repressing factor", "NHP2-like protein 1", "NLR family member X1", "NRBP family", "NSFL1 cofactor p47", "Na+/K+-ATPases", "Nardilysin", "Neuferricin", "Neurolysin, mitochondrial", "Neuropathy target esterase", "Neuroplastin", "Neutral alpha-glucosidase AB", "Neutral amino acid transporter B(0)", "Nibrin", "Nicotinamide phosphoribosyltransferase", "Non-POU domain-containing octamer-binding protein", "Non-histone chromosomal protein HMG-14", "Non-histone chromosomal protein HMG-17", "Non-motor actin binding protein", "Non-motor microtubule binding protein", "Non-protein kinase", "Nuclear RNA export factor 1", "Nuclear cap-binding protein subunit 1", "Nuclear migration protein nudC", "Nuclear pore complex protein Nup107", "Nuclear pore complex protein Nup153", "Nuclear pore complex protein Nup160", "Nuclear pore complex protein Nup214", "Nuclear pore complex protein Nup85", "Nuclear pore complex protein Nup88", "Nuclear pore complex protein Nup93", "Nuclear pore complex protein Nup98-Nup96", "Nuclear pore glycoprotein p62", "Nuclear pore membrane glycoprotein 210", "Nuclear receptor coactivator 5", "Nuclear receptor-binding protein", "Nuclease", "Nucleic acid binding", "Nucleobindin-1", "Nucleobindin-2", "Nucleolar MIF4G domain-containing protein 1", "Nucleolar complex protein 4 homolog", "Nucleolar protein 14", "Nucleolar protein 56", "Nucleolar protein 58", "Nucleolar protein 6", "Nucleolin", "Nucleophosmin", "Nucleoporin Nup37", "Nucleoporin SEH1", "Nucleoporin p54", "Nucleoside diphosphate kinase A", "Nucleoside diphosphate kinase B", "Nucleoside kinase", "Nucleosome assembly protein 1-like 1", "Nucleosome assembly protein 1-like 4", "Nucleotide kinase", "Nucleotide phosphatase", "Nucleotidyltransferase", "NudC domain-containing protein 2", "OCIA domain-containing protein 1", "OTU domain-containing protein 4", "Obg-like ATPase 1", "Origin recognition complex subunit 3", "Ornithine aminotransferase, mitochondrial", "Other 7TM proteins", "Other group", "Other small molecule kinase", "Oxidase", "Oxidoreductase", "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial", "Oxygenase", "P-type ATPases", "P38 subfamily", "P53-like transcription factor", "PAKA subfamily", "PASK subfamily", "PC4 and SFRS1-interacting protein", "PDHK family", "PDZ and LIM domain protein 1", "PDZ and LIM domain protein 5", "PEK family", "PH-interacting protein", "PHD finger protein 3", "PHD finger protein 6", "PI3/PI4 kinase family", "PIKK family", "PIN2/TERF1-interacting telomerase inhibitor 1", "PKA family", "PKN family", "PLK family", "Paired amphipathic helix protein Sin3a", "Palmitoyl-protein thioesterase 1", "Pantothenate kinase 4", "Paraspeckle component 1", "Pas domain-containing serine/threonine-protein kinase", "Paxillin", "Peptidase M20 domain-containing protein 2", "Peptidyl-prolyl cis-trans isomerase FKBP1A", "Peptidyl-prolyl cis-trans isomerase FKBP4", "Peptidyl-prolyl cis-trans isomerase FKBP5", "Peptidyl-prolyl cis-trans isomerase-like 1", "Peptidyl-prolyl cis-trans isomerase-like 3", "Perilipin-3", "Periodic tryptophan protein 1 homolog", "Peripheral plasma membrane protein cask", "Peroxidase", "Peroxiredoxin-2", "Peroxiredoxin-4", "Peroxiredoxin-6", "Peroxisomal NADH pyrophosphatase NUDT12", "Peroxisomal acyl-coenzyme A oxidase 1", "Peroxisomal acyl-coenzyme A oxidase 3", "Peroxisomal biogenesis factor 19", "Peroxisomal membrane protein PEX14", "Peroxisomal membrane protein PMP34", "Peroxisomal targeting signal 1 receptor", "Peroxisomal trans-2-enoyl-CoA reductase", "Pescadillo homolog", "Phenylalanine--tRNA ligase beta subunit", "Phosphatase", "Phosphatase activator", "Phosphatase inhibitor", "Phosphatase modulator", "Phosphate carrier protein, mitochondrial", "Phosphatidylethanolamine-binding protein 1", "Phosphatidylinositol 4-kinase type 2-alpha", "Phosphatidylinositol 4-phosphate 3-kinase c2 domain-containing subunit alpha", "Phosphatidylinositol transfer protein alpha isoform", "Phosphatidylinositol transfer protein beta isoform", "Phosphatidylinositol-binding clathrin assembly protein", "Phosphatidylserine synthase 1", "Phosphodiesterase", "Phosphoenolpyruvate carboxykinase [GTP] family", "Phosphoenolpyruvate carboxykinase [gtp], mitochondrial", "Phosphofructokinase type A (PFKA) family", "Phosphoglycerate kinase 1", "Phosphoglycerate kinase family", "Phosphoinositide 3-kinase (PI3K) family", "Phospholipase", "Phosphoribosyl pyrophosphate synthase-associated protein 1", "Phosphoribosyl pyrophosphate synthase-associated protein 2", "Phosphorylase", "Phosphorylated adapter RNA export protein", "Pirin", "Plasma membrane calcium-transporting ATPase 1", "Plasminogen activator inhibitor 1 RNA-binding protein", "Plastin-1", "Plastin-3", "Plectin", "Pogo transposable element with ZNF domain", "Poly(A) RNA polymerase, mitochondrial", "Poly(A) polymerase alpha", "Poly(A)-specific ribonuclease PARN", "Poly(rC)-binding protein 1", "Poly(rC)-binding protein 2", "Polyadenylate-binding protein-interacting protein 1", "Polycomb protein SUZ12", "Polyglutamine-binding protein 1", "Polymerase", "Polymerase delta-interacting protein 3", "Polypeptide N-acetylgalactosaminyltransferase 1", "Polypeptide N-acetylgalactosaminyltransferase 2", "Polyribonucleotide 5'-hydroxyl-kinase Clp1", "Polyribonucleotide nucleotidyltransferase 1, mitochondrial", "Pre-mRNA-processing factor 39", "Pre-mRNA-processing factor 6", "Pre-mRNA-processing-splicing factor 8", "Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15", "Pre-mRNA-splicing factor CWC22 homolog", "Pre-mRNA-splicing factor SPF27", "Pre-mRNA-splicing factor SYF1", "Prefoldin subunit 2", "Prefoldin subunit 3", "Prefoldin subunit 5", "Presequence protease, mitochondrial", "Primase", "Probable ATP-dependent RNA helicase DHX37", "Probable ATP-dependent RNA helicase DHX40", "Probable U3 small nucleolar RNA-associated protein 11", "Probable cysteine--tRNA ligase, mitochondrial", "Probable global transcription activator SNF2L1", "Probable glutamate--tRNA ligase, mitochondrial", "Probable helicase with zinc finger domain", "Probable leucine--tRNA ligase, mitochondrial", "Probable serine carboxypeptidase CPVL", "Probable tRNA N6-adenosine threonylcarbamoyltransferase", "Probable tRNA pseudouridine synthase 1", "Procollagen galactosyltransferase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2", "Programmed cell death 6-interacting protein", "Programmed cell death protein 4", "Programmed cell death protein 5", "Prolactin regulatory element-binding protein", "Proliferating cell nuclear antigen", "Prolyl 3-hydroxylase 1", "Prolyl endopeptidase", "Propionyl-CoA carboxylase alpha chain, mitochondrial", "Propionyl-CoA carboxylase beta chain, mitochondrial", "Prostaglandin E synthase 2", "Prostaglandin E synthase 3", "Prostaglandin reductase 1", "Prostaglandin reductase 2", "Prostaglandin reductase 3", "Protease", "Protease inhibitor", "Proteasome inhibitor PI31 subunit", "Protein AATF", "Protein BUD31 homolog", "Protein CMSS1", "Protein DDI1 homolog 2", "Protein ERGIC-53", "Protein FAM177A1", "Protein FRG1", "Protein LSM14 homolog A", "Protein LSM14 homolog B", "Protein NDRG3", "Protein PAT1 homolog 1", "Protein PRRC2A", "Protein PRRC2C", "Protein RRP5 homolog", "Protein Red", "Protein S100-A10", "Protein S100-A11", "Protein SCO1 homolog, mitochondrial", "Protein SCO2 homolog, mitochondrial", "Protein SET", "Protein VAC14 homolog", "Protein Wiz", "Protein XRP2", "Protein arginine N-methyltransferase 1", "Protein arginine N-methyltransferase 3", "Protein arginine N-methyltransferase 5", "Protein arginine methyltransferase", "Protein farnesyltransferase subunit beta", "Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha", "Protein gpr107", "Protein kinase", "Protein kinase C and casein kinase substrate in neurons protein 2", "Protein lin-28 homolog B", "Protein methyltransferase", "Protein phosphatase", "Protein phosphatase 1F", "Protein phosphatase 1G", "Protein phosphatase methylesterase 1", "Protein polybromo-1", "Protein quaking", "Protein regulator of cytokinesis 1", "Protein transport protein Sec23A", "Protein transport protein Sec24A", "Protein transport protein Sec24C", "Protein transport protein Sec31A", "Protein transport protein Sec61 subunit alpha isoform 1", "Protein tweety homolog 3", "Protein unc-119 homolog A", "Protein unc-119 homolog B", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase", "Protein/nucleic acid deglycase DJ-1", "Pterin-4-alpha-carbinolamine dehydratase", "Pumilio homolog 1", "Purine nucleoside phosphorylase", "Puromycin-sensitive aminopeptidase", "Putative oxidoreductase GLYR1", "Putative phospholipase B-like 2", "Pyridoxal kinase", "Pyridoxine kinase family", "Pyridoxine-5'-phosphate oxidase", "Pyrophosphatase", "Pyruvate carboxylase, mitochondrial", "Pyruvate kinase pkm", "RAD53 family", "RNA 3'-terminal phosphate cyclase-like protein", "RNA binding motif protein, X-linked-like-1", "RNA binding protein", "RNA helicase", "RNA-binding motif protein, X chromosome", "RNA-binding protein 12", "RNA-binding protein 12B", "RNA-binding protein 14", "RNA-binding protein 26", "RNA-binding protein 27", "RNA-binding protein 3", "RNA-binding protein 4", "RNA-binding protein EWS", "RNA-binding protein FUS", "RNA-binding protein Nova-2", "RNA-binding protein with serine-rich domain 1", "ROCK subfamily", "RSK family", "RSK subfamily", "Rab GDP dissociation inhibitor alpha", "Rab GDP dissociation inhibitor beta", "Rab GTPase-activating protein 1", "Rab3 GTPase-activating protein non-catalytic subunit", "Rac GTPase-activating protein 1", "Rac-alpha serine/threonine-protein kinase", "Rac-beta serine/threonine-protein kinase", "Radixin", "Ran GTPase-activating protein 1", "Ran-binding protein 3", "Ran-binding protein 9", "Ran-specific GTPase-activating protein", "Rap guanine nucleotide exchange factor 2", "Ras GTPase-activating protein 1", "Ras GTPase-activating protein-binding protein 1", "Ras GTPase-activating protein-binding protein 2", "Ras GTPase-activating-like protein IQGAP1", "Ras-related C3 botulinum toxin substrate 1", "Reader", "Receptor", "Receptor expression-enhancing protein 5", "Reductase", "Regulation of nuclear pre-mRNA domain-containing protein 1A", "Regulation of nuclear pre-mRNA domain-containing protein 1B", "Regulator of nonsense transcripts 1", "Regulator of nonsense transcripts 2", "Remodeling and spacing factor 1", "Replication factor C subunit 2", "Replication factor C subunit 3", "Replication factor C subunit 4", "Replication factor C subunit 5", "Replication origin binding protein", "Replication protein A 70 kDa DNA-binding subunit", "Reticulocalbin-1", "Reticulocalbin-2", "Retinal dehydrogenase 2", "Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta", "Retinoid-inducible serine carboxypeptidase", "Retinol dehydrogenase 11", "Retinol dehydrogenase 14", "Rho GDP-dissociation inhibitor 1", "Rho-associated protein kinase 2", "Rho-related GTP-binding protein RhoG", "Ribonuclease H2 subunit A", "Ribonuclease P protein subunit p25-like protein", "Ribonuclease P protein subunit p30", "Ribonuclease inhibitor", "Ribonucleoprotein", "Ribonucleoprotein PTB-binding 1", "Ribonucleoside-diphosphate reductase large subunit", "Ribonucleoside-diphosphate reductase subunit M2", "Ribosomal L1 domain-containing protein 1", "Ribosomal RNA small subunit methyltransferase NEP1", "Ribosomal protein", "Ribosomal protein s6 kinase alpha-1", "Ribosomal protein s6 kinase alpha-3", "Ribosome biogenesis protein BOP1", "Ribosome biogenesis protein BRX1 homolog", "Ribosome biogenesis regulatory protein homolog", "Ribosome maturation protein SBDS", "Ribosome production factor 2 homolog", "Ribosome-recycling factor, mitochondrial", "S-adenosylhomocysteine hydrolase-like protein 1", "S-adenosylmethionine mitochondrial carrier protein", "S-adenosylmethionine synthase isoform type-2", "S-formylglutathione hydrolase", "S-methyl-5'-thioadenosine phosphorylase", "S-phase kinase-associated protein 1", "S1 RNA-binding domain-containing protein 1", "SAP30-binding protein", "SEC23-interacting protein", "SET domain", "SLC superfamily of solute carriers", "SLC1 family of amino acid transporters", "SLC12 family of cation-coupled chloride transporters", "SLC16 family of monocarboxylate transporters", "SLC19 family of vitamin transporters", "SLC22 family of organic cation and anion transporters", "SLC25 family of mitochondrial transporters", "SLC27 family of fatty acid transporters", "SLC28 and SLC29 families of nucleoside transporters", "SLC29 family", "SLC3 and SLC7 families of heteromeric amino acid transporters (HATs)", "SLC3 family", "SLC30 zinc transporter family", "SLC35 family of nucleotide sugar transporters", "SLC55 Mitochondrial cation/proton exchangers", "SLC56 Sideroflexins", "SLC57 NiPA-like magnesium transporter family", "SLC61 Molybdate transporter family", "SLK subfamily", "SNARE protein", "SNW domain-containing protein 1", "SRPK family", "STAM-binding protein", "STE group", "STE20 family", "STE7 family", "SUMO-activating enzyme subunit 1", "SUMO-activating enzyme subunit 2", "SUN domain-containing protein 1", "SUN domain-containing protein 2", "SURP and G-patch domain-containing protein 1", "SURP and G-patch domain-containing protein 2", "SWI/SNF complex subunit SMARCC1", "SWI/SNF complex subunit SMARCC2", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1", "Sarcoplasmic/endoplasmic reticulum calcium ATPase 2", "Scavenger receptor class B member 1", "Sec1 family domain-containing protein 1", "Secretory carrier-associated membrane protein 1", "Secretory carrier-associated membrane protein 2", "Secretory carrier-associated membrane protein 3", "Selenocysteine-specific elongation factor", "Sentrin-specific protease 3", "Septin-11", "Septin-2", "Septin-6", "Septin-7", "Septin-9", "Serine hydroxymethyltransferase, cytosolic", "Serine hydroxymethyltransferase, mitochondrial", "Serine palmitoyltransferase 1", "Serine palmitoyltransferase 2", "Serine protease", "Serine protease inhibitor", "Serine--tRNA ligase, cytoplasmic", "Serine--tRNA ligase, mitochondrial", "Serine/arginine repetitive matrix protein 1", "Serine/arginine-rich splicing factor 1", "Serine/arginine-rich splicing factor 10", "Serine/arginine-rich splicing factor 11", "Serine/arginine-rich splicing factor 3", "Serine/arginine-rich splicing factor 5", "Serine/arginine-rich splicing factor 6", "Serine/arginine-rich splicing factor 7", "Serine/arginine-rich splicing factor 9", "Serine/threonine-protein kinase 4", "Serine/threonine-protein kinase chk2", "Serine/threonine-protein kinase mark2", "Serine/threonine-protein kinase mtor", "Serine/threonine-protein kinase n2", "Serine/threonine-protein kinase nek9", "Serine/threonine-protein kinase osr1", "Serine/threonine-protein kinase pak 2", "Serine/threonine-protein kinase plk1", "Serine/threonine-protein kinase prp4 homolog", "Serine/threonine-protein kinase vrk1", "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform", "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform", "Serine/threonine-protein phosphatase 2A activator", "Serine/threonine-protein phosphatase 4 regulatory subunit 1", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit", "Serine/threonine-protein phosphatase PP1-beta catalytic subunit", "Serpin B6", "Serpin H1", "Sex comb on midleg-like protein 2", "Sialic acid synthase", "Sideroflexin-1", "Sigma intracellular receptor 2", "Signal peptidase complex catalytic subunit SEC11A", "Signal peptidase complex subunit 2", "Signal peptidase complex subunit 3", "Signal peptide peptidase-like 2A", "Signal recognition particle 14 kDa protein", "Signal recognition particle 54 kDa protein", "Signal recognition particle 9 kDa protein", "Signal recognition particle receptor subunit alpha", "Signal recognition particle subunit SRP68", "Signal transducer and activator of transcription 1-alpha/beta", "Signal transducer and activator of transcription 3", "Signaling", "Single-stranded DNA-binding protein, mitochondrial", "Sister chromatid cohesion protein PDS5 homolog A", "Sister chromatid cohesion protein PDS5 homolog B", "Small GTPase", "Small nuclear ribonucleoprotein E", "Small nuclear ribonucleoprotein Sm D1", "Small nuclear ribonucleoprotein Sm D2", "Small nuclear ribonucleoprotein Sm D3", "Sodium/potassium-transporting ATPase subunit alpha-1", "Sodium/potassium-transporting ATPase subunit beta-3", "Solute carrier family 12 member 2", "Solute carrier family 35 member F2", "Sorbitol dehydrogenase", "Sorting nexin-1", "Sorting nexin-2", "Spermatid perinuclear RNA-binding protein", "Spermidine synthase", "Splicing factor 1", "Splicing factor 3A subunit 1", "Splicing factor 3A subunit 2", "Splicing factor 3A subunit 3", "Splicing factor 3B subunit 1", "Splicing factor 3B subunit 3", "Splicing factor 45", "Splicing factor U2AF 35 kDa subunit", "Splicing factor, proline- and glutamine-rich", "Splicing factor, suppressor of white-apricot homolog", "Splicing regulatory glutamine/lysine-rich protein 1", "Squalene monooxygenase", "Squamous cell carcinoma antigen recognized by T-cells 3", "Src substrate cortactin", "Srsf protein kinase 1", "Staphylococcal nuclease domain-containing protein 1", "Ste20-like serine/threonine-protein kinase", "Sterol O-acyltransferase 1", "Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating", "Stomatin-like protein 2, mitochondrial", "Storage", "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial", "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial", "Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial", "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial", "Succinate-semialdehyde dehydrogenase, mitochondrial", "Sulfhydryl oxidase 2", "Superoxide dismutase [Mn], mitochondrial", "Surfeit locus protein 4", "Surfeit locus protein 6", "Survival motor neuron protein", "Synaptic functional regulator FMR1", "Synaptic vesicle glycoprotein 2A", "Synaptogyrin-2", "Synaptojanin-2-binding protein", "Synaptosomal-associated protein 23", "Synaptosomal-associated protein 29", "Syntaxin-10", "Syntaxin-12", "Syntaxin-17", "Syntaxin-18", "Syntaxin-4", "Syntaxin-5", "Syntaxin-7", "Syntaxin-8", "Syntaxin-binding protein 3", "Syntenin-1", "T-complex protein 1 subunit alpha", "T-complex protein 1 subunit beta", "T-complex protein 1 subunit delta", "T-complex protein 1 subunit epsilon", "T-complex protein 1 subunit eta", "T-complex protein 1 subunit gamma", "T-complex protein 1 subunit theta", "T-complex protein 1 subunit zeta", "TAK1 subfamily", "TATA-binding protein-associated factor 2N", "TBC1 domain family member 15", "TBC1 domain family member 4", "TBC1 domain family member 9B", "THO complex subunit 1", "THO complex subunit 3", "THO complex subunit 4", "TK group", "TKL group", "TOPK family", "TP53-binding protein 1", "TTK family", "Target of EGR1 protein 1", "Targeting protein for Xklp2", "Terminal uridylyltransferase 4", "Testin", "Testis-specific Y-encoded-like protein 1", "Tgf-beta-activated kinase 1 and map3k7-binding protein 1", "Thimet oligopeptidase", "Thioredoxin domain-containing protein 12", "Thioredoxin domain-containing protein 17", "Thioredoxin domain-containing protein 9", "Thioredoxin reductase 1, cytoplasmic", "Thioredoxin-dependent peroxide reductase, mitochondrial", "Threonine--tRNA ligase, cytoplasmic", "Threonine--tRNA ligase, mitochondrial", "Thymidine kinase family", "Thymidine kinase, cytosolic", "Thymidylate kinase", "Thymidylate kinase family", "Thymidylate synthase", "Thyroid hormone receptor-associated protein 3", "Tight junction", "Tight junction protein ZO-1", "Trafficking protein particle complex subunit 4", "Trans-Golgi network integral membrane protein 2", "Transaminase", "Transcription activator BRG1", "Transcription cofactor", "Transcription elongation factor A protein 1", "Transcription elongation factor SPT6", "Transcription elongation regulator 1", "Transcription factor", "Transcriptional activator protein Pur-alpha", "Transcriptional repressor p66-alpha", "Transcriptional repressor p66-beta", "Transferase", "Transferrin receptor protein 1", "Transformer-2 protein homolog alpha", "Transformer-2 protein homolog beta", "Transforming protein RhoA", "Transgelin-2", "Transketolase", "Translation elongation factor", "Translation factor", "Translation initiation factor", "Translation initiation factor IF-2, mitochondrial", "Translation release factor", "Translationally-controlled tumor protein", "Translocation protein SEC63 homolog", "Translocon-associated protein subunit alpha", "Transmembrane 9 superfamily member 2", "Transmembrane 9 superfamily member 3", "Transmembrane emp24 domain-containing protein 10", "Transmembrane emp24 domain-containing protein 2", "Transmembrane emp24 domain-containing protein 7", "Transport and Golgi organization protein 1 homolog", "Transporter", "Transportin-1", "Transportin-2", "Tricarboxylate transport protein, mitochondrial", "Trifunctional enzyme subunit alpha, mitochondrial", "Trifunctional enzyme subunit beta, mitochondrial", "Trifunctional purine biosynthetic protein adenosine-3", "Triosephosphate isomerase", "Tripeptidyl-peptidase 1", "Tripeptidyl-peptidase 2", "Tropomodulin-3", "Tropomyosin alpha-3 chain", "Tropomyosin alpha-4 chain", "Tryptophan--tRNA ligase, cytoplasmic", "Tuberin", "Tubulin", "Tubulin beta chain", "Tubulin beta-2A chain", "Tubulin beta-2B chain", "Tubulin beta-4A chain", "Tubulin beta-4B chain", "Tubulin beta-6 chain", "Tubulin-folding cofactor B", "Tubulin-specific chaperone A", "Tubulin-specific chaperone D", "Tubulin-specific chaperone E", "Tudor and KH domain-containing protein", "Tudor domain", "Tuftelin-interacting protein 11", "Tumor susceptibility gene 101 protein", "Twinfilin-1", "Twinfilin-2", "Twinkle protein, mitochondrial", "Type II PI4K subfamily", "Tyrosine--tRNA ligase, cytoplasmic", "Tyrosine--tRNA ligase, mitochondrial", "Tyrosine-protein kinase csk", "U1 small nuclear ribonucleoprotein 70 kDa", "U1 small nuclear ribonucleoprotein A", "U2 small nuclear ribonucleoprotein A'", "U2 small nuclear ribonucleoprotein B''", "U2 snRNP-associated SURP motif-containing protein", "U3 small nucleolar RNA-associated protein 14 homolog A", "U3 small nucleolar RNA-associated protein 6 homolog", "U3 small nucleolar ribonucleoprotein protein IMP3", "U3 small nucleolar ribonucleoprotein protein MPP10", "U4/U6 small nuclear ribonucleoprotein Prp3", "U4/U6 small nuclear ribonucleoprotein Prp31", "U4/U6 small nuclear ribonucleoprotein Prp4", "U4/U6.U5 tri-snRNP-associated protein 1", "U4/U6.U5 tri-snRNP-associated protein 2", "U6 snRNA-associated Sm-like protein LSm2", "U6 snRNA-associated Sm-like protein LSm6", "UDP-glucose:glycoprotein glucosyltransferase 1", "UMP-CMP kinase", "UV excision repair protein RAD23 homolog B", "Ubiquitin carboxyl-terminal hydrolase 10", "Ubiquitin carboxyl-terminal hydrolase 11", "Ubiquitin carboxyl-terminal hydrolase 14", "Ubiquitin carboxyl-terminal hydrolase 19", "Ubiquitin carboxyl-terminal hydrolase 28", "Ubiquitin carboxyl-terminal hydrolase 33", "Ubiquitin carboxyl-terminal hydrolase 47", "Ubiquitin carboxyl-terminal hydrolase 5", "Ubiquitin carboxyl-terminal hydrolase 7", "Ubiquitin carboxyl-terminal hydrolase isozyme L5", "Ubiquitin conjugation factor E4 A", "Ubiquitin thioesterase OTUB1", "Ubiquitin-conjugating enzyme E2 L3", "Ubiquitin-like modifier-activating enzyme 1", "Ubiquitin-like modifier-activating enzyme 6", "Ubiquitin-like-conjugating enzyme ATG3", "Ubiquitin-protein ligase", "Unclassified protein", "Unconventional myosin-Ib", "Unconventional myosin-Ic", "Unconventional myosin-Id", "Unconventional myosin-VI", "Uridine kinase family", "Uridine-cytidine kinase 2", "V-type ATPase", "V-type proton ATPase 116 kDa subunit a isoform 1", "V-type proton ATPase 116 kDa subunit a isoform 2", "V-type proton ATPase catalytic subunit A", "V-type proton ATPase subunit B, brain isoform", "V-type proton ATPase subunit C 1", "V-type proton ATPase subunit D", "V-type proton ATPase subunit H", "V-type proton ATPase subunit d 1", "VRK family", "Vacuolar protein sorting-associated protein 18 homolog", "Vacuolar protein sorting-associated protein 26A", "Vacuolar protein sorting-associated protein 29", "Vacuolar protein sorting-associated protein 33A", "Vacuolar protein sorting-associated protein 35", "Vacuolar protein sorting-associated protein 4A", "Very long-chain specific acyl-CoA dehydrogenase, mitochondrial", "Very-long-chain enoyl-CoA reductase", "Vesicle coat protein", "Vesicle-associated membrane protein 7", "Vesicle-associated membrane protein-associated protein A", "Vesicle-associated membrane protein-associated protein B/C", "Vesicle-fusing ATPase", "Vesicular integral-membrane protein VIP36", "WD repeat and HMG-box DNA-binding protein 1", "WD repeat-containing protein 1", "WD repeat-containing protein 82", "WEE family", "Winged helix/forkhead transcription factor", "Writer", "X-ray repair cross-complementing protein 5", "X-ray repair cross-complementing protein 6", "Xaa-Pro dipeptidase", "Zinc finger CCCH domain-containing protein 11A", "Zinc finger CCCH domain-containing protein 15", "Zinc finger CCHC domain-containing protein 8", "Zinc finger MYM-type protein 4", "Zinc finger RNA-binding protein", "Zinc finger protein 622", "Zinc finger protein ubi-d4", "Zinc finger transcription factor", "Zinc transporter 5", "Zyxin", "[pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial", "eIF-2-alpha kinase activator GCN1", "eukaryotic two domain clade \"e\" sub-subfamily", "m7GpppX diphosphatase", "mRNA export factor", "mRNA polyadenylation factor", "mRNA processing factor", "mRNA splicing factor", "pre-mRNA 3' end processing protein WDR33", "rRNA 2'-O-methyltransferase fibrillarin", "tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6", "tRNA (cytosine(34)-C(5))-methyltransferase", "tRNA (guanine-N(7)-)-methyltransferase", "tRNA pseudouridine synthase A"], "available_proteins": ["AARS", "AARS2", "AARSD1", "AASDHPPT", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCC1", "ABCC4", "ABCD3", "ABCF1", "ABCF2", "ABCF3", "ABHD12", "ABHD6", "ACAA1", "ACAA2", "ACAD11", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACLY", "ACO2", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP2", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADH5", "ADI1", "ADK", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGL", "AHCY", "AHCYL1", "AIFM1", "AIMP1", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALYREF", "ANP32A", "ANP32B", "ANP32E", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP3B1", "AP3D1", "AP3M1", "APEH", "APOL2", "ARCN1", "ARFIP1", "ARFIP2", "ARHGDIA", "ARIH1", "ARPC1A", "ARPC1B", "ARPC3", "ARPC4", "ARPC5", "AS3MT", "ASAH1", "ASNA1", "ASNS", "ASRGL1", "ATAD3A", "ATAD3B", "ATG3", "ATG4B", "ATIC", "ATL2", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP6", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "ATP7B", "ATPAF1", "ATPIF1", "ATXN2L", "AUP1", "BAG6", "BAIAP2", "BAK1", "BAX", "BCAP31", "BCAS2", "BCAT2", "BCLAF1", "BET1", "BLMH", "BLVRA", "BLVRB", "BOP1", "BPNT1", "BRD2", "BRIX1", "BUB3", "BUD31", "BZW1", "BZW2", "CAB39", "CACYBP", "CAD", "CALR", "CALU", "CAND1", "CANX", "CAP1", "CAPN1", "CAPRIN1", "CAPZA1", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP2", "CASP3", "CASP6", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD276", "CD2BP2", "CDC37", "CDC42", "CDC45", "CDK1", "CDK13", "CDK2", "CDK4", "CDK6", "CDKN2AIP", "CEBPZ", "CEP170", "CFAP20", "CHAF1A", "CHAF1B", "CHEK2", "CHERP", "CHKA", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHUK", "CIRBP", "CKAP5", "CKB", "CKMT1A*", "CLASP2", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLNS1A", "CLP1", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT7", "CNP", "COASY", "COIL", "COL4A3BP", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS3", "COPS5", "COPS6", "COPS8", "COPZ1", "CORO1C", "COTL1", "COX2", "COX5A", "COX5B", "COX7A2", "COX7C", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT2", "CPVL", "CRNKL1", "CRTAP", "CS", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNND1", "CTPS1", "CTPS2", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL4B", "CUL5", "CWC22", "CYB5B", "CYB5D2", "CYFIP1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DBN1", "DBNL", "DCAF13", "DCPS", "DCTN1", "DCTN2", "DDB1", "DDI2", "DDOST", "DENR", "DERL1", "DERL2", "DHCR24", "DHFR", "DHX15", "DHX29", "DHX37", "DHX40", "DHX8", "DHX9", "DICER1", "DIDO1", "DIEXF", "DIS3", "DLD", "DLST", "DNM1", "DNM1L", "DNM2", "DNMT1", "DPF2", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DSG2", "DSP", "DST", "DTYMK", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "EARS2", "EBP", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC4", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EHD1", "EHMT1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3H", "EIF3I", "EIF3J", "EIF3L", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELMO2", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP3", "EMC2", "EMG1", "ENO1", "ENOPH1", "EPHX2", "EPPK1", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERC1", "ERH", "ERI1", "ERMP1", "ERO1A", "ERP29", "ESD", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "FAHD1", "FAM177A1", "FARSB", "FASN", "FBL", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FKBP1A", "FKBP4", "FKBP5", "FMR1", "FN3KRP", "FNTA", "FNTB", "FOXC1", "FOXRED1", "FRG1", "FSCN1", "FUBP1", "FUBP3", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GCAT", "GCFC2", "GCLM", "GCN1", "GDI1", "GDI2", "GFPT1", "GGH", "GINS1", "GINS2", "GLB1", "GLDC", "GLRX3", "GLRX5", "GLS", "GLTP", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNE", "GNG12", "GNG5", "GNPDA1", "GNS", "GPATCH4", "GPD2", "GPI", "GPKOW", "GPR107", "GPT2", "GRHPR", "GRPEL1", "GRSF1", "GSPT1", "GSR", "GSS", "GTF3C3", "GTF3C5", "GTPBP1", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADHA", "HADHB", "HAT1", "HBS1L", "HCCS", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HEATR1", "HELZ", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLCS", "HM13", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGN1", "HMGN2", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HPRT1", "HSD17B10", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HTATSF1", "HUWE1", "IARS", "IARS2", "IDE", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "ILF3", "ILKAP", "ILVBL", "IMP3", "IMPAD1", "IMPDH2", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "ITCH", "ITGB1", "ITPA", "ITPK1", "IVD", "KARS", "KAT7", "KCTD12", "KDELR1", "KDM1A", "KDM1B", "KDM3B", "KHDRBS1", "KHSRP", "KIF11", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRR1", "KYAT3", "L2HGDH", "LAMP1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS2", "LBR", "LDHA", "LDHB", "LETM1", "LGALS3", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LNPEP", "LONP1", "LPCAT1", "LRRC47", "LRWD1", "LSM14A", "LSM14B", "LSM2", "LSM6", "LTN1", "M6PR", "MACF1", "MAGED2", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARK2", "MAT2A", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED25", "METTL1", "MFN2", "MFSD5", "MGST2", "MGST3", "MIA3", "MICU1", "MICU2", "MIPEP", "MMS19", "MORF4L1", "MORF4L2", "MPG", "MPHOSPH10", "MPI", "MPP2", "MPP6", "MPRIP", "MPST", "MPV17L2", "MRPL1", "MRPL11", "MRPL12", "MRPL14", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL38", "MRPL39", "MRPL44", "MRPL9", "MRPS2", "MRPS27", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR6", "MTOR", "MTPAP", "MUT", "MVK", "MYBBP1A", "MYEF2", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA25", "NAA35", "NAA50", "NADK2", "NAE1", "NAGK", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NBN", "NCAPD2", "NCAPD3", "NCBP1", "NCL", "NCOA5", "NDRG3", "NDUFA10", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA8", "NDUFA9", "NDUFB11", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS7", "NEDD4", "NEK9", "NFS1", "NHP2", "NIPA2", "NKRF", "NLN", "NLRX1", "NME1", "NME2", "NMT1", "NNT", "NOC4L", "NOL6", "NOM1", "NONO", "NOP14", "NOP56", "NOP58", "NOVA2", "NPEPPS", "NPM1", "NPTN", "NRBP1", "NRDC", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSUN2", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDCD2", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUF2", "NUP107", "NUP153", "NUP160", "NUP210", "NUP214", "NUP37", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "OAT", "OCIAD1", "OCRL", "OLA1", "OPA1", "ORC3", "OSGEP", "OTUB1", "OTUD4", "OXA1L", "OXSR1", "P3H1", "PACSIN2", "PAICS", "PAIP1", "PAK2", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PASK", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PDCD11", "PDCD4", "PDCD5", "PDCD6IP", "PDE12", "PDE6D", "PDK3", "PDLIM1", "PDLIM5", "PDS5A", "PDS5B", "PDXK", "PEBP1", "PECR", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PGD", "PGK1", "PGLS", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHF3", "PHF6", "PHGDH", "PHIP", "PI4K2A", "PICALM", "PIGK", "PIK3C2A", "PINX1", "PIR", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN2", "PLA2G15", "PLBD2", "PLCG1", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PNP", "PNPLA6", "PNPO", "PNPT1", "POGZ", "POLA2", "POLDIP3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLRMT", "PPA1", "PPA2", "PPAT", "PPIL1", "PPIL3", "PPM1F", "PPM1G", "PPME1", "PPP1CA", "PPP1CB", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP4R1", "PPT1", "PPT2", "PQBP1", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX6", "PREB", "PREP", "PRIM1", "PRKAA1", "PRKACA", "PRKAG1", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF3", "PRPF31", "PRPF39", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC2A", "PRRC2C", "PSIP1", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSMF1", "PSPC1", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PUM1", "PURA", "PUS1", "PWP1", "PXN", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "QSOX2", "RAB3GAP2", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RAD23B", "RAE1", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAPGEF2", "RASA1", "RAVER1", "RBBP6", "RBM12", "RBM12B", "RBM14", "RBM17", "RBM26", "RBM27", "RBM3", "RBM4", "RBMX", "RBMXL1", "RCL1", "RCN1", "RCN2", "RDH11", "RDH14", "RDX", "RECQL", "RECQL4", "REEP5", "RFC2", "RFC3", "RFC4", "RFC5", "RHOA", "RHOG", "RHOT1", "RHOT2", "RNASEH2A", "RNF14", "RNH1", "RNPS1", "ROCK2", "RP2", "RPA1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRM1", "RRM2", "RRS1", "RSF1", "RSL1D1", "S100A10", "S100A11", "SAE1", "SAP18", "SAP30BP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCFD1", "SCML2", "SCO1", "SCO2", "SCPEP1", "SDCBP", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC23A", "SEC23IP", "SEC24A", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEH1L", "SENP3", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD7", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B3", "SFPQ", "SFSWAP", "SFXN1", "SHMT1", "SHMT2", "SIN3A", "SIRT1", "SIRT2", "SKP1", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC30A5", "SLC35B2", "SLC35F2", "SLC3A2", "SLK", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMN1*", "SMYD3", "SNAP23", "SNAP29", "SND1", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SOAT1", "SOD2", "SORD", "SPAG9", "SPCS2", "SPCS3", "SPPL2A", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SREK1", "SRM", "SRP14", "SRP54", "SRP68", "SRP9", "SRPK1", "SRPRA", "SRRM1", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "STAG2", "STAMBP", "STAT1", "STAT3", "STK4", "STOML2", "STRBP", "STT3A", "STT3B", "STX10", "STX12", "STX17", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP3", "SUCLA2", "SUCLG2", "SUGP1", "SUGP2", "SUN1", "SUN2", "SUPT16H", "SUPT6H", "SURF4", "SURF6", "SUZ12", "SV2A", "SYNCRIP", "SYNGR2", "SYNJ2BP", "TAB1", "TAF15", "TAGLN2", "TARS", "TARS2", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TCEA1", "TCERG1", "TCP1", "TDRKH", "TECR", "TES", "TFIP11", "TFRC", "TGOLN2", "THOC1", "THOC3", "THOP1", "THRAP3", "TIMM22", "TJP1", "TK1", "TKT", "TM9SF2", "TM9SF3", "TMED10", "TMED2", "TMED7", "TMEM97", "TMOD3", "TMPO", "TNPO1", "TNPO2", "TOE1", "TOMM20", "TOMM40", "TOP1", "TP53", "TP53BP1", "TPI1", "TPM3", "TPM4", "TPP1", "TPP2", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAP1", "TRAPPC4", "TRMT6", "TROVE2", "TRUB1", "TSC2", "TSFM", "TSG101", "TSPYL1", "TSTA3", "TTK", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC9", "TXNRD1", "TYMS", "U2AF1", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA6", "UBE2L3", "UBE4A", "UCHL5", "UCK2", "UGGT1", "UNC119", "UNC119B", "UPF1", "UPF2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "USO1", "USP10", "USP11", "USP14", "USP19", "USP28", "USP33", "USP39", "USP47", "USP5", "USP7", "UTP11", "UTP14A", "UTP6", "VAC14", "VAMP7", "VAPA", "VAPB", "VBP1", "VPS18", "VPS26A", "VPS29", "VPS33A", "VPS35", "VPS4A", "VRK1", "VRK3", "WARS", "WDHD1", "WDR1", "WDR33", "WDR82", "WIZ", "XAB2", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "YARS", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H15", "ZCCHC11", "ZCCHC8", "ZFR", "ZMPSTE24", "ZMYM4", "ZNF598", "ZNF622", "ZW10", "ZYX"], "leading_proteins": ["AATF", "ABCB10", "ABCB7", "ABCC1", "ABCC4", "ABHD12", "ACOX1", "ACOX3", "ADPGK", "AK1", "AKT1", "AKT2", "ANP32B", "ANP32E", "AP1B1", "ARFIP1", "ARFIP2", "ATG4B", "ATP2B1", "ATP2C1", "ATP5I", "ATP6", "ATP6V1B2", "BAG6", "BAIAP2", "BRIX1", "CASP3", "CCNB1", "CDK13", "CHKA", "CHMP7", "CLIC4", "CLNS1A", "COL4A3BP", "CPOX", "CYB5B", "DHCR24", "DNM2", "DPM1", "DPYSL3", "DYNC1LI2", "EHD1", "EIF3F", "EMG1", "ERAL1", "ERAP1", "EXOC4", "EXOC6", "FDXR", "GABARAPL2", "GLTP", "GMFB", "GNAI2", "GNG5", "GPT2", "H1F0", "H1FX", "H2AFX", "H2AFY2", "H4C1*", "HDHD2", "HINT2", "HIST1H1C", "HIST1H1E", "HSP90AB1", "IGF2BP2", "ILKAP", "IMPAD1", "IPO11", "IPO8", "KDM1A", "KIF1A", "KIF23", "KIF2A", "KIF2C", "LETM1", "M6PR", "MAP2K2", "MAP3K7", "MAPK14", "MARK2", "MCU", "MED25", "MFN2", "MRPL12", "MRPL14", "MRPL17", "MRPL19", "MRPL38", "MRPL9", "MRPS27", "MRPS35", "MRPS5", "MRRF", "MSMO1", "MTCH2", "MTOR", "NAP1L1", "NAP1L4", "NOP14", "NPTN", "NRBP1", "NUCB2", "OCRL", "OXA1L", "OXSR1", "PCK2", "PCMT1", "PDCD5", "PDK3", "PDXK", "PES1", "PIGK", "PIR", "PKMYT1", "POLR2E", "PPM1F", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX6", "PRKAG1", "PSMD14", "PSMD4", "PTPA", "RABGAP1", "RACGAP1", "RASA1", "RBM12", "RHOG", "RPL10A", "RPL12", "RPL13", "RPL22", "RPL23", "RPL23A", "RPL27", "RPL28", "RPL29", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL38", "RPL7", "RPL7A", "RPL9", "RPN2", "RPRD1B", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS18", "RPS19", "RPS2", "RPS6", "RPS7", "RPS8", "RPS9", "RPSA", "SAP30BP", "SCARB1", "SEPT6", "SEPT9", "SERPINH1", "SET", "SLC25A10", "SLC25A21", "SLC25A26", "SLC25A32", "SLC30A5", "SLC35B2", "SLC35F2", "SNAP23", "SNAP29", "SNX1", "SPPL2A", "STK4", "STT3B", "SUN1", "SURF4", "SYNGR2", "TAB1", "TIMM22", "TM9SF3", "TPP1", "TRAP1", "TSPYL1", "TUBB2A", "TUBB4A", "TUBB4B", "TUBGCP2", "TUBGCP3", "UGGT1", "UNC119", "UNC119B", "UQCR10", "UQCRB", "USP33", "VPS18", "VPS26A", "VRK1", "VRK3", "XPO4", "YME1L1", "ZMPSTE24"]} \ No newline at end of file diff --git a/pharos_protein_category/advanced/idx2term.json b/pharos_protein_category/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/pharos_protein_category/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/pharos_protein_category/basic/idx2term.json b/pharos_protein_category/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..1e34e34f6a79d9cccb1734a1422c265c7ec5c879 --- /dev/null +++ b/pharos_protein_category/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Tbio", "1": "Tdark", "2": "Tclin"} \ No newline at end of file diff --git a/pharos_protein_category/basic/plot_0.png b/pharos_protein_category/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..4f086141f4184dcb319367542e4bcd331c894561 --- /dev/null +++ b/pharos_protein_category/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:86c91d108247c342b451d4e6aac6916de60c932dfff92fa2a8fdb1298bbfdd28 +size 124760 diff --git a/pharos_protein_category/basic/plot_1.png b/pharos_protein_category/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..a824f5629b8de7acc31792ea8c62487d6e5846ef --- /dev/null +++ b/pharos_protein_category/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c4538262e4f2e41b2bafaf3b6d2317e39e119613a058b409f79772c202392a06 +size 133662 diff --git a/pharos_protein_category/basic/plot_2.png b/pharos_protein_category/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..33bc910ad6859f840d744ce946e3b15fa83b4a0f --- /dev/null +++ b/pharos_protein_category/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d2318d1f81a9869897c90ae4471a0720ce4d13948da1ef3030b40cfecbe212b6 +size 137084 diff --git a/pharos_protein_category/consensus.joblib b/pharos_protein_category/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..464d851c02cf3cf041e03a31ac3f2c5637beac0c --- /dev/null +++ b/pharos_protein_category/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a6181464944384952b66a8d9132d3eca5ecb31e8cef9d2c606824ea5ced3ff19 +size 61053 diff --git a/pharos_protein_category/df_merge.tsv b/pharos_protein_category/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/pharos_protein_category/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/pharos_protein_category/metrics.json b/pharos_protein_category/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..efeeab9d539b20ff3bd2394734c8934d77670425 --- /dev/null +++ b/pharos_protein_category/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2772, + "annotations_size": 4, + "title": "Average number of proteins per term", + "value": 692.75 +} \ No newline at end of file diff --git a/pharos_protein_category/paths.json b/pharos_protein_category/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..b11f0a683def68c859c8d3f7dfc9e79b007a7a73 --- /dev/null +++ b/pharos_protein_category/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_protein_category/fragment/C321/C321_val_log2fc"} \ No newline at end of file diff --git a/pharos_protein_category/result.tsv b/pharos_protein_category/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..fe1b3fd81c66aeb2c958748fa094f493ff3a0a58 --- /dev/null +++ b/pharos_protein_category/result.tsv @@ -0,0 +1,4 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Tbio 0.192311618731444 1.611183863798711 0.107139653752845 0.3644728011071385 0.2320186144085054 2150 Q13505,Q9UQB8,A6NIH7,O95747,P19388,Q99595,Q8IUH4,P80303,O94761,Q16822,Q9Y237,Q15165,P09455,Q9Y5P4,Q9HCC0,Q8N5C6,P00846,P04899,Q14728,Q8NCC3,Q9NS69,O14773,O75844,Q53HL2,Q969T9,P22570,P54105,O75027,O95793,Q9Y6M1,Q9Y639,Q8TCT8,Q8NE86,Q8N4Q0,O60637,Q13217,P35244,P20645,P22061,Q76FK4,Q9BQT8,Q96A65,O95456,Q96EY1,Q96KP1,O00148,O00764,O00487,Q9UDW1,Q8IZT6,Q06136,O43768,Q7Z7K6,Q70HW3,Q9H074,Q15070,Q9BUN8,Q9NZM5,P53365,Q9UII2,O94842,P20339,P49593,Q9Y4P1,O43169,P42695,Q06265,Q7L592,Q9C0H2,O15173,P42766,Q9Y282,Q14789,P13051,Q9UI26,Q9BVC6,Q15427,P80723,P81605,O14737,O00303,Q9NWT1,Q9Y3B8,Q9UHG3,Q9UNE7,Q8NE01,P55145,O95674,Q13057,Q8TEY7,Q9UHY1,Q9NY61,Q9C0E2,Q8TED0,Q9NUJ1,Q15102,P78310,P14927,P07196,Q9NVI7,Q9Y5L4,Q9NZD2,O43760,Q6P4A7,O00461,O43396,P35609,Q5JTV8,Q71SY5,Q92783,Q9Y3U8,P62899,Q9Y2R5,Q8N5W9,Q5VUA4,Q15392,Q8TAD4,P62841,O75915,O75448,O00625,P16403,Q96PU8,Q9Y3C6,Q96ST3,Q9Y376,Q8TBC4,Q14241,O43237,P26038,Q15800,Q2NKX8,Q96T37,Q96TA2,Q96HY6,Q9Y584,Q5JPH6,P17096,Q13084,P55036,P20936,O14925,Q01968,Q9UHR5,Q16763,Q10567,O75190,Q04837,Q9NQ50,Q9H0H5,Q96KA5,Q96A33,P16383,P60520,P56385,O94973,Q9Y3P9,Q9NYU2,Q9NVN8,Q8WUX9,Q8TB61,Q14195,Q7Z5K2,P61353,P51648,P14923,P61457,Q96F86,Q96SZ5,Q96RL7,Q9Y508,Q96CW5,P46379,P46100,O94901,Q7Z4G4,Q9Y3E5,Q9NXV2,P62314,Q16630,P15924,O95202,O75832,O75223,Q9Y312,Q9Y276,Q9UFW8,Q9H9Y6,Q9H2U1,Q9BQ95,Q969S3,Q86XP3,Q14527,P18077,O95197,P11940,O95478,P58546,P63218,Q8IWJ2,Q9UER7,Q9BS26,Q9BQ39,Q92643,Q6IBS0,Q4V328,Q14141,Q13596,Q12756,P55039,O15254,Q8WWK9,Q9UBB9,Q9P253,Q9NQW6,Q9H2D1,Q9BZD4,Q9BQG2,Q96KM6,O60762,Q86YP4,P62861,Q7L2J0,P04844,P28370,O95429,Q13867,Q5JRA6,Q5SRE5,Q9UBX3,Q9P0M6,Q9NTI5,Q9H4M9,Q9BU89,Q96JJ3,Q96G23,P62244,Q15067,P62269,P50748,P49589,P39019,P28072,P62750,Q8TD30,Q15404,Q8TAE8,Q8TCJ2,Q9BX68,Q99986,Q9UDX5,P61088,Q8NE71,P40222,O95721,O15212,O95140,O75436,P05204,P07197,P07954,P09669,P10412,Q9HDC9,Q8TB37,Q99797,Q9BRX5,Q9BV86,Q9H0U9,Q9Y3A2,Q9NQG5,Q9NSV4,Q9NWS0,Q9Y333,Q8IWS0,Q8TAG9,O14745,P05387,Q04323,O00161,O00139,O43592,P04179,P16949,P35659,P54619,Q02241,Q13823,Q9Y680,Q9H0C8,Q8NBU5,Q86U42,Q6NUM9,Q5ST30,Q53EZ4,Q02952,P67812,P53367,P30533,P22033,P08240,O76024,Q6IAA8,Q8NBJ5,Q8WW12,Q9BRR6,Q9UBD5 307 +Tdark 0.3159432072518352 1.2655148812653698 0.2056868172940291 0.6019230041064736 0.2742490897253722 256 O60830,Q6PI78,Q8NBN3,Q96DV4,Q8NHQ9,Q9Y3D9,Q6UW02,Q9HC38,Q9H4I3,Q6P1L8,O95302,P82664,Q9P265,Q9NX62,Q9NPR9,Q9NRX2,Q8N4V1,P84157,Q69YU5,Q6ZT21,Q5TC12,Q52LJ0,Q9HBM1,Q3B7T1,Q9P2N5,Q9BYD2,Q9BSH5,P78316,Q9NWH9,Q9Y2W6,Q9H1E5,Q5SWX8,Q8NC96,P42696,Q96P11,A0AVF1,Q9UJA5,Q9NVZ3,Q9NX00,Q8IXU6,P58107,Q5HYI7 42 +Tclin 0.2617696294457665 0.2133708346798303 0.8310377272542244 0.999184997444124 0.8310377272542244 78 P68371,P04350,P36507,Q16881,P10253,P51970,P49721,Q86Y39,Q99808,Q9UGN5,Q9NX14,O75489,Q16795,Q16718,Q07864,O75116,O75306,P00374,O43676,Q13885,O75251,P31350 22 diff --git a/pharos_protein_category/selections.json b/pharos_protein_category/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..bb2a420a80abed684c00cfde4d2066d540c074de --- /dev/null +++ b/pharos_protein_category/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Tbio", "Tchem", "Tclin", "Tdark"], "available_proteins": ["AAAS", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAP2", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADH5", "ADI1", "ADK", "ADNP", "ADO", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP17A", "AKAP8", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT1S1", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALKBH5", "ALYREF", "AMOT", "ANAPC16", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANKRD28", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP3B1", "AP3D1", "AP3M1", "APEH", "APEX1", "API5", "APMAP", "APOL2", "APOOL", "APRT", "AQR", "ARCN1", "ARF4", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL6IP4", "ARL6IP5", "ARL8B", "ARMC1", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "AS3MT", "ASAH1", "ASCC2", "ASCC3", "ASNA1", "ASNS", "ASPH", "ASPM", "ASRGL1", "ATAD1", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATG4B", "ATIC", "ATL2", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7B", "ATPAF1", "ATPIF1", "ATRX", "ATXN10", "ATXN2L", "AUP1", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAK1", "BANF1", "BAP18", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BCAP31", "BCAS2", "BCAT2", "BCCIP", "BCL10", "BCL2L12", "BCL2L13", "BCLAF1", "BCS1L", "BET1", "BIRC6", "BLMH", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOP1", "BPNT1", "BRD2", "BRI3BP", "BRIX1", "BSG", "BTF3", "BUB3", "BUD31", "BYSL", "BZW1", "BZW2", "C11orf58", "C12orf43", "C12orf73", "C15orf39", "C19orf25", "C19orf70", "C1QBP", "C1orf123", "C1orf35", "C20orf27", "C21orf59", "C2CD2", "C2CD5", "C2orf49", "C5orf15", "CAB39", "CACUL1", "CACYBP", "CAD", "CALD1", "CALR", "CALU", "CAND1", "CANX", "CAP1", "CAPN1", "CAPRIN1", "CAPZA1", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP2", "CASP3", "CASP6", "CAST", "CBFB", "CBR1", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC124", "CCDC47", "CCDC6", "CCDC86", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD276", "CD2AP", "CD2BP2", "CD47", "CD81", "CDC123", "CDC23", "CDC27", "CDC37", "CDC42", "CDC45", "CDC5L", "CDC73", "CDCA8", "CDK1", "CDK13", "CDK2", "CDK4", "CDK5RAP3", "CDK6", "CDKAL1", "CDKN2A", "CDKN2AIP", "CDS2", "CDV3", "CEBPZ", "CELF1", "CELF2", "CENPV", "CEP170", "CEP44", "CEP55", "CERS2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP2A", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP2", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLP1", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTA", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNOT1", "CNOT11", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG7", "COIL", "COL4A3BP", "COLGALT1", "COMMD10", "COMMD2", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "CORO1C", "COTL1", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZL1", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWC22", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DCAF13", "DCAF7", "DCAKD", "DCD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHFR", "DHPS", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX40", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIP2B", "DIS3", "DIS3L2", "DKC1", "DLAT", "DLD", "DLST", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOHH", "DPF2", "DPH2", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DRG1", "DRG2", "DSG2", "DSP", "DST", "DSTN", "DTL", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFL1", "EFTUD2", "EHD1", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENDOD1", "ENO1", "ENOPH1", "ENSA", "ENY2", "EPB41", "EPB41L2", "EPB41L3", "EPHX1", "EPHX2", "EPPK1", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERC1", "ERCC2", "ERCC6L", "ERGIC3", "ERH", "ERI1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EYA3", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAHD2A", "FAM114A2", "FAM120A", "FAM120B", "FAM136A", "FAM162A", "FAM177A1", "FAM208A", "FAM3C", "FAM49B", "FAM8A1", "FAM91A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FAU", "FBL", "FBXO22", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FLCN", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNBP4", "FNDC3A", "FNTA", "FNTB", "FOXC1", "FOXRED1", "FRG1", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLM", "GCN1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GHITM", "GIGYF2", "GINS1", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLTP", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GNS", "GOLGA3", "GOLGB1", "GOLIM4", "GOPC", "GOT1", "GOT2", "GPAA1", "GPATCH4", "GPD2", "GPI", "GPKOW", "GPR107", "GPR108", "GPS1", "GPT2", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2E1", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP4", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS4", "HAUS5", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDGFL2", "HDHD2", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEBP1", "HECTD1", "HELLS", "HELZ", "HERC2", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HP1BP3", "HPRT1", "HPS6", "HS1BP3", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "ILF2", "ILF3", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPAD1", "IMPDH2", "INA", "INCENP", "INF2", "INTS3", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IRF2BPL", "IRS4", "ISCU", "ISOC1", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPK1", "IVD", "JPT2", "JUP", "KARS", "KAT7", "KCTD12", "KCTD5", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM3B", "KDSR", "KHDRBS1", "KHSRP", "KIAA0368", "KIF11", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KLC1", "KLC2", "KLC4", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LAMP1", "LAMTOR1", "LAMTOR2", "LANCL1", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDAH", "LDHA", "LDHB", "LEMD3", "LENG8", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRCH2", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC59", "LRWD1", "LSG1", "LSM12", "LSM14A", "LSM14B", "LSM2", "LSM6", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LZTFL1", "LZTS2", "M6PR", "MACF1", "MAGED2", "MAK16", "MANF", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MCAT", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED17", "MED24", "MED25", "MEPCE", "MESD", "METTL1", "METTL13", "MFF", "MFN2", "MFSD10", "MFSD5", "MGEA5", "MGST2", "MGST3", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MIPEP", "MKI67", "MLEC", "MMAB", "MMGT1", "MMS19", "MOGS", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP2", "MPP6", "MPRIP", "MPST", "MPV17L2", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL44", "MRPL45", "MRPL46", "MRPL50", "MRPL58", "MRPL9", "MRPS10", "MRPS15", "MRPS17", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTX1", "MTX2", "MTX3", "MUT", "MVD", "MVK", "MXRA7", "MYBBP1A", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA25", "NAA35", "NAA40", "NAA50", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCAPH2", "NCBP1", "NCDN", "NCK1", "NCKAP1", "NCL", "NCLN", "NCOA5", "NCSTN", "NDC1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4", "NEFL", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NFS1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPA2", "NIPSNAP2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NME1", "NME2", "NMT1", "NNT", "NOC2L", "NOC3L", "NOC4L", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOSIP", "NOVA2", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NSA2", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSMCE2", "NSUN2", "NSUN5", "NSUN6", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDT1", "NUDT12", "NUDT16L1", "NUDT21", "NUDT5", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCRL", "ODR4", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC3", "OSBP", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OTULIN", "OXA1L", "OXSR1", "P3H1", "P4HA1", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAK1IP1", "PAK2", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PASK", "PATL1", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDS5A", "PDS5B", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF2", "PHF3", "PHF5A", "PHF6", "PHGDH", "PHIP", "PI4K2A", "PICALM", "PIGK", "PIGS", "PIGU", "PIH1D1", "PIK3C2A", "PIN1", "PIN4", "PINX1", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN2", "PLA2G15", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PMVK", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPO", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPHLN1", "PPIB", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R1", "PPP5C", "PPT1", "PPT2", "PQBP1", "PRAF2", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF39", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTRH2", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXN", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB21", "RAB24", "RAB34", "RAB35", "RAB39A", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB8B", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD51AP1", "RAE1", "RAI14", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP1GDS1", "RAPGEF2", "RARS", "RASA1", "RAVER1", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM8A", "RBMX", "RBMXL1", "RBP1", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "REEP5", "RER1", "RETREG2", "RETREG3", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFLNB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RINT1", "RMDN1", "RMDN3", "RNASEH2A", "RNASEH2B", "RNASET2", "RNF114", "RNF14", "RNF40", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP3", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSBN1", "RSF1", "RSL1D1", "RSU1", "RTCB", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMHD1", "SAMM50", "SAP18", "SAP30BP", "SAR1A", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDCBP", "SDE2", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC63", "SEH1L", "SEL1L", "SENP3", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD7", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN4", "SGPL1", "SGTA", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIN3A", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC30A5", "SLC35A4", "SLC35B2", "SLC35F2", "SLC3A2", "SLC4A1AP", "SLC9A3R1", "SLFN11", "SLIRP", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SMYD3", "SMYD5", "SNAP23", "SNAP29", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SOAT1", "SOD2", "SON", "SORD", "SPAG9", "SPART", "SPATA5L1", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPECC1L", "SPEN", "SPOUT1", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STIM2", "STIP1", "STK4", "STMN1", "STOML2", "STRAP", "STRBP", "STRN", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX17", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SULT2A1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACC3", "TACO1", "TAF15", "TAGLN2", "TALDO1", "TAMM41", "TARDBP", "TARS", "TARS2", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF25", "TCOF1", "TCP1", "TDP2", "TDRKH", "TECR", "TELO2", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFG", "TFIP11", "TFRC", "TGOLN2", "THOC1", "THOC3", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "TIA1", "TIAL1", "TIMELESS", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TK1", "TKT", "TLN1", "TM9SF2", "TM9SF3", "TMA16", "TMCO1", "TMED10", "TMED2", "TMED7", "TMEM109", "TMEM11", "TMEM126A", "TMEM14C", "TMEM160", "TMEM192", "TMEM199", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM33", "TMEM43", "TMEM65", "TMEM87A", "TMEM97", "TMOD3", "TMPO", "TMPO", "TMPPE", "TMTC3", "TMX1", "TMX2", "TMX4", "TNPO1", "TNPO2", "TOE1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOR1AIP2", "TOX4", "TP53", "TP53BP1", "TPD52", "TPD52L2", "TPI1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRIM21", "TRIM25", "TRIM27", "TRIM28", "TRIP12", "TRIP13", "TRMT10C", "TRMT11", "TRMT112", "TRMT2A", "TRMT6", "TROVE2", "TRUB1", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPYL1", "TSR1", "TSTA3", "TTC1", "TTC19", "TTC26", "TTC37", "TTC38", "TTC4", "TTI1", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE2V1", "UBE3C", "UBE4A", "UBLCP1", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UFSP2", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "UROD", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP19", "USP28", "USP33", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VPS13A", "VPS18", "VPS26A", "VPS29", "VPS33A", "VPS35", "VPS4A", "VPS51", "VPS53", "VRK1", "VRK3", "WAPL", "WARS", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR18", "WDR3", "WDR33", "WDR36", "WDR41", "WDR43", "WDR46", "WDR5", "WDR6", "WDR61", "WDR70", "WDR73", "WDR75", "WDR77", "WDR82", "WFS1", "WIPI2", "WIZ", "WRAP53", "WTAP", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YKT6", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZDHHC13", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM4", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF598", "ZNF622", "ZNF638", "ZNF687", "ZPR1", "ZRANB2", "ZW10", "ZYX"], "leading_proteins": ["AAR2", "AATF", "ABCB7", "ABCF1", "ABHD10", "ACOX1", "ACOX3", "ACTN2", "ADO", "ADPGK", "AKAP12", "ALDH3A2", "ANLN", "AP1B1", "AP2A2", "APMAP", "ARFIP1", "ARFIP2", "ARL6IP5", "ASPM", "ATAD1", "ATAD3A", "ATG4B", "ATP5I", "ATP6", "ATPAF1", "ATPIF1", "ATRX", "BAG4", "BAG6", "BAIAP2", "BASP1", "BCS1L", "BLMH", "C12orf73", "CAB39", "CARS", "CCDC47", "CDCA8", "CDS2", "CENPV", "CEP55", "CERS2", "CGGBP1", "CHMP7", "CKAP2", "CLNS1A", "CLPTM1L", "CNNM3", "COASY", "COL4A3BP", "COLGALT1", "COX6C", "CPSF6", "CXADR", "CYB5B", "CYP20A1", "DAXX", "DCD", "DDRGK1", "DDX39A", "DDX42", "DDX50", "DDX55", "DEK", "DERL1", "DHCR24", "DHFR", "DHX36", "DIAPH3", "DIP2B", "DNAJA3", "DNAJB6", "DNAJC3", "DOHH", "DPM1", "DPYSL3", "DRG2", "DSP", "DYNC1LI2", "EARS2", "ECSIT", "EDC3", "EDRF1", "EHD1", "EIF3F", "ELMO2", "ELOA", "ENSA", "EPPK1", "ERCC6L", "ERGIC3", "ERP44", "EXOC2", "EXOC4", "EXOC6", "EXOSC9", "FAM98B", "FAU", "FDXR", "FH", "FKBP7", "FKBP9", "GAA", "GABARAPL2", "GADD45GIP1", "GATAD2A", "GCC2", "GCFC2", "GGCT", "GINS3", "GLOD4", "GLTP", "GNAI2", "GNG5", "GNL2", "GNL3L", "GOLGB1", "GOLIM4", "GPR108", "GPT2", "GRIPAP1", "H2AFY2", "HDHD3", "HINT2", "HIST1H1C", "HIST1H1E", "HLTF", "HMGA1", "HMGN2", "IGF2BP2", "ILKAP", "IMPAD1", "IPO11", "JUP", "KCTD5", "KDSR", "KIF1A", "KIF23", "KIF2A", "KNTC1", "LAMTOR1", "LETM1", "LRPAP1", "LSM2", "M6PR", "MANF", "MAP2K2", "MCCC2", "MCU", "MED24", "MED25", "MEPCE", "MFN2", "MFSD10", "MIA3", "MIPEP", "MMGT1", "MRPL14", "MRPL17", "MRPL28", "MRPL38", "MRPL40", "MRPL9", "MRPS10", "MRPS17", "MRPS23", "MSMO1", "MSN", "MTFP1", "MTPN", "MTX1", "MTX3", "MUT", "MXRA7", "NCAPD3", "NDUFA11", "NDUFA5", "NDUFA8", "NDUFA9", "NDUFAF7", "NDUFB11", "NDUFB3", "NDUFS2", "NDUFS3", "NDUFS7", "NECAP1", "NECAP2", "NEFL", "NEFM", "NOL8", "NOP14", "NOP53", "NPTN", "NRBP1", "NSA2", "NSUN5", "NTMT1", "NUBPL", "NUCB2", "NUDT12", "NUF2", "NUP188", "OCRL", "ODR4", "ORC3", "OXA1L", "OXSR1", "PABPC1", "PABPN1", "PAFAH1B3", "PAIP1", "PAK1IP1", "PARP2", "PCBD1", "PCK2", "PCMT1", "PCNP", "PCYOX1", "PDCD5", "PDS5B", "PDXK", "PFDN6", "PGRMC2", "PHF6", "PIGK", "PIH1D1", "PIN4", "PIR", "PLA2G15", "POLE", "POLR1B", "POLR2E", "PON2", "PPIL1", "PPM1F", "PRKAG1", "PSMB2", "PSMB6", "PSMD10", "PSMD14", "PSMD4", "PSMG1", "PTRH2", "QKI", "RAB5A", "RABGAP1", "RACGAP1", "RASA1", "RBM15", "RBM27", "RBM34", "RBP1", "RECQL4", "RETSAT", "REXO2", "RFLNB", "RNF114", "ROCK2", "RPA3", "RPL23A", "RPL27", "RPL31", "RPL35", "RPL35A", "RPL36", "RPLP2", "RPN2", "RPRD1B", "RPS15", "RPS15A", "RPS18", "RPS19", "RRM2", "RSU1", "RTN3", "SAP30BP", "SEC11A", "SEPT6", "SF3B4", "SFXN4", "SIN3A", "SLC25A10", "SLC25A21", "SLC25A26", "SLC25A32", "SLC29A1", "SLC30A5", "SLC35B2", "SLC35F2", "SLC9A3R1", "SLTM", "SMARCA1", "SNAP23", "SNAP29", "SNRPD1", "SNX1", "SOD2", "SPC25", "SPPL2A", "SRBD1", "SRPRA", "SSBP1", "STAM", "STAU1", "STMN1", "STT3B", "STUB1", "SUN1", "SYNGR2", "TDRKH", "TFIP11", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TMEM109", "TMEM160", "TMEM65", "TMEM87A", "TMPPE", "TMX4", "TOMM22", "TOR1AIP1", "TOX4", "TPP1", "TRABD", "TRMT11", "TRMT6", "TSPAN3", "TSPYL1", "TTC26", "TTYH3", "TUBB2A", "TUBB4A", "TUBB4B", "TUBGCP3", "TWF2", "TXLNA", "TXNL1", "TXNRD1", "UBA3", "UBE2N", "UBE2S", "UBXN1", "UGGT1", "UNC119B", "UNG", "UQCR10", "UQCRB", "USP33", "UTP11", "UTP15", "VARS2", "VPS13A", "VPS18", "VPS26A", "VRK1", "WAPL", "WBP2", "WFS1", "XPO4", "XPOT", "YME1L1", "ZADH2", "ZDHHC13", "ZMPSTE24", "ZNF318", "ZNF512B", "ZNF622"]} \ No newline at end of file diff --git a/protein_atlas_biological_process/advanced/idx2term.json b/protein_atlas_biological_process/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..b9f1bd82459103a571b0212a862648e9d160b484 --- /dev/null +++ b/protein_atlas_biological_process/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Transport", "1": "Protein transport", "2": "Electron transport", "3": "Translocation", "4": "Apoptosis"} \ No newline at end of file diff --git a/protein_atlas_biological_process/advanced/plot_0.png b/protein_atlas_biological_process/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..7d2eecf3e52cd0057118c546f165ebcdd8c0c1aa --- /dev/null +++ b/protein_atlas_biological_process/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:edd3eeed32e0703e61770755dadaa4638591ffad5f717e412c44328623ef5c6e +size 230453 diff --git a/protein_atlas_biological_process/advanced/plot_1.png b/protein_atlas_biological_process/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..e93c521d15642ebdee7c5ae161880e5f9e8a9c76 --- /dev/null +++ b/protein_atlas_biological_process/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2a8769ccda25c0721ff60692b3ca8dff7300e5440427cf71ae7a20bacb81094a +size 220302 diff --git a/protein_atlas_biological_process/advanced/plot_2.png b/protein_atlas_biological_process/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..0d73aa55a339f12ca3acf3e9ac6c9e219202099e --- /dev/null +++ b/protein_atlas_biological_process/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1e00f1ab869522c2439d8383e6d1476027019fba16707adade3fca706b78b502 +size 206095 diff --git a/protein_atlas_biological_process/advanced/plot_3.png b/protein_atlas_biological_process/advanced/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..d8ad647900d2907440aee1833d13763b06af916f --- /dev/null +++ b/protein_atlas_biological_process/advanced/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fd0a324025a67f4d450ef2fda5b8f0cc7dc462645c39a49ae0af296e4cdd59c3 +size 200975 diff --git a/protein_atlas_biological_process/advanced/plot_4.png b/protein_atlas_biological_process/advanced/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..bb48c2c2741ae724623d016cc7481cc156fc4752 --- /dev/null +++ b/protein_atlas_biological_process/advanced/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:366ca13f555b52181f26bf34aefbccee2c444dfb205d787ff7d72e9e7fe34c1e +size 215452 diff --git a/protein_atlas_biological_process/basic/idx2term.json b/protein_atlas_biological_process/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..6bc2db306ff1396df4b35cee0f69fc16d9364149 --- /dev/null +++ b/protein_atlas_biological_process/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Transport", "1": "Protein transport", "2": "Electron transport", "3": "Translocation", "4": "Apoptosis", "5": "Respiratory chain", "6": "Ion transport", "7": "Translation regulation", "8": "Endocytosis", "9": "Spermatogenesis", "10": "Cell division", "11": "Mitosis", "12": "Autophagy", "13": "Carbohydrate metabolism"} \ No newline at end of file diff --git a/protein_atlas_biological_process/basic/plot_0.png b/protein_atlas_biological_process/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..b9821c603c292c1356bf48a70e72182f844f6f07 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:589b4da90e1aecc19fc4f6021decc084ed382db21bdace43f3f1461b1101301c +size 136813 diff --git a/protein_atlas_biological_process/basic/plot_1.png b/protein_atlas_biological_process/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..86e98ce43b0cb3630267340f0d8d7cb776b93132 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7b7732016c466787fb7726a22e44be6e981a2b44161c7119e62d1f9889eb2859 +size 139622 diff --git a/protein_atlas_biological_process/basic/plot_10.png b/protein_atlas_biological_process/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..c719286fa111aedf826ec1bf883b843eec48faca --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:06d2951c3e94e5c8206205917ef95dcec9cd219343cdb0a92146bf02f1317635 +size 139480 diff --git a/protein_atlas_biological_process/basic/plot_11.png b/protein_atlas_biological_process/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..828694b1f2c8df2652300d1e9e7092eb8c3d34cf --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9b321cb37abed4aa4390585986174d57b9586435318a1425dad6388fe1063c31 +size 139941 diff --git a/protein_atlas_biological_process/basic/plot_12.png b/protein_atlas_biological_process/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..8b7a8ad02e87e501d589a83227c8029b00f8ac8b --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c57c37c093d474d42da0f761e5ebc7191ccf6bd8f95395644268ff08bc8aa458 +size 134217 diff --git a/protein_atlas_biological_process/basic/plot_13.png b/protein_atlas_biological_process/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..334d6d6082b18f7d2b423642fa5d91899268e10b --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1d2b3cbe8fbe1824bc43058be57997e385d6ed09f75b1c5bcb0b596e2f0b7859 +size 153190 diff --git a/protein_atlas_biological_process/basic/plot_2.png b/protein_atlas_biological_process/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..644038e6aaae21fa99f9fa874ed2246aca4c508f --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a4072db660430351db270bbb1d9707eda2fb67a583fe0aa3f5223b8f0a57be85 +size 133901 diff --git a/protein_atlas_biological_process/basic/plot_3.png b/protein_atlas_biological_process/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..6a66a004fb19d8121c2b0832d5ce518c21f94e0c --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f2e213ee0913ed8641a57dea69e300f93b6e5c06edfd39c51fd991efa32e9189 +size 129852 diff --git a/protein_atlas_biological_process/basic/plot_4.png b/protein_atlas_biological_process/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..ea40be8df70aa979c1f0a92b4c222c5444e0ebee --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0f2c69aa41cd89995c5026453cb061cc4a4246c425f44cfdaa667cbb7d8ce58e +size 136058 diff --git a/protein_atlas_biological_process/basic/plot_5.png b/protein_atlas_biological_process/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..dfe37ba627a4f4fadbbd7c7a9d498170bc98cf3c --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:23705dcf36a75ea9ec0251bfc2ed759e80d5fede5026c52c1f8e674764dda223 +size 139090 diff --git a/protein_atlas_biological_process/basic/plot_6.png b/protein_atlas_biological_process/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..114715e4e2502cc4c4049f771a0b4147d1bf8691 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f4cc35b308fb21e5191c86cd8e0695569a9388fa5c2ea1b31b29092ca5069427 +size 133396 diff --git a/protein_atlas_biological_process/basic/plot_7.png b/protein_atlas_biological_process/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..ab713c92185cb9048d6d57000b45b576e7b3ee32 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:084df4da9d137a82be48e175cb794d9bd4df9d17f9e64dadf7c5e7841fffdf43 +size 142267 diff --git a/protein_atlas_biological_process/basic/plot_8.png b/protein_atlas_biological_process/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..eeb777fce8f26cf40b261227297a0d377a2c9ac8 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bd893fbb7b0371b5bfa5081d4704110bf514549b891bd961a6abf7feb2c168c3 +size 137381 diff --git a/protein_atlas_biological_process/basic/plot_9.png b/protein_atlas_biological_process/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..975cd2de2c5dd6dabe9b0d6873942cd9492477f1 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d367e06b6b84f366c9ecdb692db30d648c1cbc2f931d7924a47e0ac0ea1b19be +size 137086 diff --git a/protein_atlas_biological_process/consensus.joblib b/protein_atlas_biological_process/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..7e5ee30bc4189a1e8350786225fb00570041a209 --- /dev/null +++ b/protein_atlas_biological_process/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c79afbb810fb6de90c6b643f3c78f1a56f3176ddccf4297fee71c077f8973d2e +size 77151 diff --git a/protein_atlas_biological_process/df_merge.tsv b/protein_atlas_biological_process/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..a52259dec55e5fb8a329a9f2e292e4f4d96022c9 --- /dev/null +++ b/protein_atlas_biological_process/df_merge.tsv @@ -0,0 +1,7 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Transport 79 421 4.921613984844961 8.583338659369786e-07 127.39320388349516 491.7621359223301 1.4832290368286314 0.5289485259644714 40.31460927260851 50.077723312236 2.248556521823017 0.4543981544818752 0.1172028246345884 0.0002530794617687 1.4994009157076793e-07 1.1874240538496976e-11 1.5235804758144015e-09 +Protein transport 36 206 3.236531887394831 0.0012099170776429 60.970873786407765 250.03155339805824 0.5647835050770387 0.6753991045983436 18.49610628700502 28.95320084782557 1.0712917387948182 0.3856428267622117 0.0543350333457543 0.1176294864432771 0.0127204031762486 0.0028155899620087 0.0010214216959798 +Electron transport 9 43 2.548571371886476 0.0108165151401531 14.983009708737864 45.592233009708735 1.1180311721330871 0.3315827540150002 5.69510117113123 4.184313965655804 1.5984402393879058 0.3574888993156041 1.0 0.3686542667077518 0.0122290647269916 9.048822549111846e-05 0.000189933732808 +Translocation 5 44 2.210522661938807 0.0270689095159386 12.434466019417476 47.86165048543689 1.1297087783550883 0.3515144245437065 6.687771513864753 3.601211391947168 1.550426642680832 0.3811939235350816 1.0 0.0050226976439289 0.0307365702447484 0.0077994913978603 0.0619746491943417 +Exocytosis 4 11 2.113498970902948 0.0345580830004983 4.512135922330097 14.946601941747574 0.0354964034281069 0.6663548673413242 2.464770869236286 2.6897978966912683 0.6646547463506557 0.2704772352886787 1.0 1.0 0.0670123246896251 0.2950567493775322 0.0664964915650886 +Apoptosis 24 108 2.005422672845228 0.0449178798488509 26.983009708737864 120.21844660194176 0.6636399997719048 0.5877814963058052 7.904294191754799 11.993762517847651 0.9312427807662368 0.388650277956022 1.0 0.5169656199025946 0.1203836638612039 0.012469236245757 0.0154094580621939 diff --git a/protein_atlas_biological_process/metrics.json b/protein_atlas_biological_process/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..d2f4fa2a9378eb202778a1226d1788a4ec9d1e75 --- /dev/null +++ b/protein_atlas_biological_process/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2772, + "annotations_size": 164, + "title": "Average number of proteins per term", + "value": 27.53048780487805 +} \ No newline at end of file diff --git a/protein_atlas_biological_process/paths.json b/protein_atlas_biological_process/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..839721887b1d1e2ca158856a32593eb441b97190 --- /dev/null +++ b/protein_atlas_biological_process/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_biological_process/fragment/C321/C321_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_biological_process/result.tsv b/protein_atlas_biological_process/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..1f1f4aa36f2dcd8d449d862d0321c313b07587e6 --- /dev/null +++ b/protein_atlas_biological_process/result.tsv @@ -0,0 +1,43 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Transport 0.4361283864103923 4.921613984844961 8.583338659369786e-07 0.0001407569072431 0.0001407667540138 421 Q13505,A6NIH7,O60830,Q99595,P09455,Q9Y5P4,P33527,P00846,Q14728,Q9NS69,P22570,O75027,Q8N4V1,Q9Y6M1,Q8NE86,P20645,Q9BQT8,Q13432,Q96A65,Q96KP1,Q9UDW1,P31749,O75489,Q70HW3,Q01469,Q9BUN8,Q9H1E5,Q8NC96,O15439,P20339,Q9Y4P1,O43169,Q9C0H2,Q9Y282,O43676,Q9UI26,Q9BVC6,Q8IXU6,Q8NE01,Q5HYI7,Q9C0E2,P14927,Q9Y5L4,Q9NZD2,Q6P4A7,O00461,O43396,Q92783,Q8TAD4,Q96PU8,Q86Y39,O43237,Q9NX14,Q9Y584,P21281,O14925,Q10567,P31751,Q9H0H5,P60520,P56385,O94973,Q8WUX9,Q8TB61,A0AVF1,Q9NVZ3,Q96RL7,P46379,O95202,Q9H2U1,O95197,Q8IWJ2,Q4V328,Q13596,Q9P253,Q9H2D1,Q5JRA6,Q5SRE5,Q9UBX3 79 +Protein transport 0.4259958157437699 3.236531887394831 0.0012099170776429 0.1800783871611995 0.0198426400733444 206 Q13505,A6NIH7,O60830,Q99595,Q9C0E2,Q9Y5L4,Q8IWJ2,Q92783,Q9NS69,Q4V328,Q13596,Q9P253,Q13432,Q9Y584,Q96A65,Q5JRA6,Q5SRE5,Q96KP1,Q9H4M9,O14925,Q10567,Q9BUN8,Q8NC96,P60520,O95721,O94973,P20339,Q9Y4P1,O75436,Q8WUX9,A0AVF1,Q9NVZ3,Q9UI26,Q96RL7,Q8TAG9,Q5HYI7 36 +Electron transport 0.5494370553786511 2.548571371886476 0.0108165151401531 0.8319631508991591 0.1043475578226538 43 O43169,P22570,Q9UDW1,O75489,P14927,Q86Y39,O43676,Q9H1E5,O43396 9 +Sugar transport 0.9259927797833928 2.3878488487723786 0.0169473102687207 0.9393829898134328 0.1462820465300107 2 P31749 1 +Translocation 0.5084547844198087 2.210522661938807 0.0270689095159386 0.9888964615810854 0.1944656299770168 44 O60830,Q99595,Q9Y5L4,Q9Y584,Q9NS69 5 +Exocytosis 0.7509603225480649 2.113498970902948 0.0345580830004983 0.9968732818287608 0.2053528383413182 11 Q96KP1,P40222,Q5JRA6,Q96A65 4 +Apoptosis 0.4014137183134307 2.005422672845228 0.0449178798488509 0.999467061333069 0.2380504707288773 108 O75832,Q03164,O95197,Q14728,Q9UER7,Q8WWK9,Q96EY1,Q96JJ3,O43318,P31749,Q9UHR5,Q9NWH9,P31751,Q9BX68,Q96KA5,Q9UDX5,P42574,Q13043,P49593,P09601,P46379,O95470,O14737,Q9Y3E5 24 +Glycogen biosynthesis 0.8671458322523369 1.9522739213825655 0.0509056919235972 0.9998100074853526 0.2482832411645434 5 P31749 1 +ATP synthesis 0.7524346714010027 1.7905173205756608 0.0733707853260541 0.9999962624921792 0.2734729271243835 8 P00846 1 +Unfolded protein response 0.6223329338095505 1.3952100909768972 0.1629524949247098 0.9999999999997856 0.3759731859271734 10 P55145,Q9BUN8,Q13217 3 +Sterol metabolism 0.4879296682498395 1.3885823219383004 0.1649597960396027 0.9999999999998554 0.3759731859271734 23 Q16850,Q15392,P22570 3 +Steroid metabolism 0.4815452370047943 1.386370858398538 0.1656336901566817 0.9999999999998732 0.3759731859271734 25 Q16850,Q15392,P22570 3 +Cholesterol metabolism 0.489873052936193 1.3846697368901475 0.1661534768561021 0.9999999999998856 0.3759731859271734 22 Q16850,Q15392,P22570 3 +Respiratory chain 0.4622814406811716 1.3831683722464876 0.1666132450768056 0.9999999999998956 0.3759731859271734 30 O75306,P51970,Q9UDW1,O75489,P14927,Q86Y39,O43676,Q16795,Q16718,Q9NX14,O14949 11 +Glycogen metabolism 0.7046802852015515 1.3820595300541922 0.1669534233132288 0.9999999999999024 0.3759731859271734 6 P31749 1 +Hydrogen ion transport 0.4761971725751227 1.235057035242202 0.2168092780665174 1.0 0.4517358768657325 20 P21281,P00846 2 +Ion transport 0.3965718002128954 1.2329230433840173 0.2176044772706882 1.0 0.4517358768657325 48 P21281,Q8TAD4,Q9C0H2,Q8NE86,Q9H0H5,Q9BVC6,P00846,P56385,Q8NE01 9 +Cilium biogenesis/degradation 0.485251848018373 1.2092068594057677 0.2265833830965504 1.0 0.4644959353479284 18 Q9H4M9,A6NIH7,Q6IBS0,Q01968 4 +Translation regulation 0.3900953307864312 1.1797161408545689 0.2381131320490954 1.0 0.4821056006919957 49 P31749,Q96PU8,Q9Y6M1,P31751,Q9H074,Q13217 6 +Endocytosis 0.4342242846975818 1.1265985989277914 0.2599122317757634 1.0 0.5198244635515268 28 Q8TEY7,O94973,Q8NC96,Q13432,P20339 5 +Spermatogenesis 0.444942490579938 1.0798484885653523 0.2802096547996953 1.0 0.5536672697246992 21 Q14141,Q9Y2W6,Q9H0H5,Q9Y508,P46379,O94901,Q9H6S0,Q14997 8 +Phagocytosis 0.7587576742506118 0.99554274059682 0.3194723676927316 1.0 0.5953803216091815 3 Q96JJ3,P20339 2 +Cell division 0.3161117525546931 0.9381534386444856 0.348165562618449 1.0 0.6344350252158404 130 Q02241,Q53EZ4,P04899,P14635,P18858,Q53HL2,Q14141,Q99661,Q9NQW6,Q9BZD4,Q2NKX8,Q9NTI5,Q9HBM1,Q8IZT6,P50748,O43768,Q7Z7K6,Q16763,Q9H0H5,Q99986,Q9BPX3,Q00839,O43663,P42695,Q7Z5K2,O00139,Q86XL3 27 +Sterol biosynthesis 0.4443419498957968 0.9071338009272228 0.3643360455313325 1.0 0.6482394480294172 16 Q16850,Q15392 2 +Cholesterol biosynthesis 0.4467390532489852 0.9014611509807706 0.3673431805719263 1.0 0.6482394480294172 15 Q16850,Q15392 2 +DNA recombination 0.4011788233916566 0.8164940731687333 0.414217611953056 1.0 0.679316883603012 23 P18858 1 +DNA synthesis 0.5599277978339297 0.7294250321757508 0.465741710203527 1.0 0.7042300201944068 2 P35232 1 +Glucose metabolism 0.4675214554391371 0.6714826992762559 0.5019130772084339 1.0 0.7349441487694924 10 P31749 1 +Pyrimidine biosynthesis 0.5261445007995191 0.6148554761874593 0.5386501687383338 1.0 0.7681619797659718 5 Q9NRF8 1 +Mitosis 0.2959966807657943 0.6018015283530348 0.547306257664399 1.0 0.768269858370771 100 Q02241,Q53EZ4,P14635,Q53HL2,Q99661,Q9NQW6,Q9BZD4,Q2NKX8,Q9NTI5,Q9HBM1,Q8IZT6,P50748,O43768,Q7Z7K6,Q99986,Q9BPX3,P42695,Q7Z5K2,O00139 19 +Lipid transport 0.3654695001007988 0.4964573209834987 0.6195717917343919 1.0 0.8109205699493569 17 Q9Y5P4 1 +Proline biosynthesis 0.6101514012211573 0.4929534271546544 0.6220454952583181 1.0 0.8109205699493569 3 P32322 1 +Biological rhythms 0.3116735255511122 0.4842414279443085 0.6282145388210263 1.0 0.8109205699493569 39 Q96ST3,Q03164 2 +Calcium transport 0.4477706355803439 0.4841857732119129 0.6282540326469683 1.0 0.8109205699493569 8 Q8NE86 1 +Chemotaxis 0.6028344010600739 0.4710437198548171 0.6376095142389735 1.0 0.8109205699493569 3 Q8NHP6 1 +Autophagy 0.3303352176669856 0.4171565605405519 0.6765638963267662 1.0 0.8342592405833807 27 Q9P253,P60520,P53365,O95721,Q9Y4P1 5 +Phospholipid biosynthesis 0.4005240849786635 0.3949654191086518 0.6928684090386972 1.0 0.8402248417337431 10 O95674,P35790,Q6UWP7 3 +Steroid biosynthesis 0.3254215904618068 0.362116319588771 0.7172651087970978 1.0 0.8402248417337431 21 Q16850,Q15392 2 +Amino-acid transport 0.5319059770984226 0.3200073698322675 0.7489627437771438 1.0 0.8539425119646682 4 Q6P4A7,P08195 2 +Carbohydrate metabolism 0.3029491807487725 0.2535885773684188 0.7998134221753799 1.0 0.8919970195556537 23 P31749,P62136,Q15120,P31751,Q96C23,Q7Z4W1,O60701 7 +Cell shape 0.3841705818576014 0.1894255957924533 0.8497592650651091 1.0 0.9229173474879332 5 Q7L576,P15311,P35580,P35579 4 +Antiviral defense 0.2727294680011306 0.1299822950811115 0.8965804343225761 1.0 0.948639943412274 22 Q9H2U1,Q13217,Q15366 3 diff --git a/protein_atlas_biological_process/selections.json b/protein_atlas_biological_process/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..ca9d63d3a1115e9404618e857566fe311bbdebbc --- /dev/null +++ b/protein_atlas_biological_process/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthesis", "Adaptive immunity", "Amino-acid biosynthesis", "Amino-acid transport", "Angiogenesis", "Antiport", "Antiviral defense", "Apoptosis", "Aromatic hydrocarbons catabolism", "Asparagine biosynthesis", "Autophagy", "B-cell activation", "Bile acid catabolism", "Biological rhythms", "Biomineralization", "Branched-chain amino acid biosynthesis", "Branched-chain amino acid catabolism", "Calcium transport", "Carbohydrate metabolism", "Catecholamine metabolism", "Cell adhesion", "Cell cycle", "Cell division", "Cell shape", "Chemotaxis", "Cholesterol biosynthesis", "Cholesterol metabolism", "Chromosome partition", "Cilium biogenesis/degradation", "Coenzyme A biosynthesis", "Collagen degradation", "Complement pathway", "Copper transport", "DNA condensation", "DNA damage", "DNA excision", "DNA recombination", "DNA repair", "DNA replication", "DNA synthesis", "Detoxification", "Differentiation", "ER-Golgi transport", "Electron transport", "Endocytosis", "Exocytosis", "Fatty acid biosynthesis", "Fatty acid metabolism", "Fertilization", "Fucose metabolism", "GMP biosynthesis", "GPI-anchor biosynthesis", "Galactose metabolism", "Gastrulation", "Gluconate utilization", "Gluconeogenesis", "Glucose metabolism", "Glutathione biosynthesis", "Glycogen biosynthesis", "Glycogen metabolism", "Glycolysis", "Glyoxylate bypass", "Growth arrest", "Growth regulation", "Hearing", "Heme biosynthesis", "Host-virus interaction", "Hydrogen ion transport", "Hypusine biosynthesis", "Immunity", "Inflammatory response", "Inhibition of host STAT1 by virus", "Inhibition of host STAT2 by virus", "Inhibition of host innate immune response by virus", "Inhibition of host interferon signaling pathway by virus", "Innate immunity", "Inositol biosynthesis", "Ion transport", "Isoprene biosynthesis", "Keratinization", "Leukotriene biosynthesis", "Lipid biosynthesis", "Lipid degradation", "Lipid metabolism", "Lipid transport", "Meiosis", "Methionine biosynthesis", "Methotrexate resistance", "Mitosis", "Molybdenum cofactor biosynthesis", "Myogenesis", "Necrosis", "Neurogenesis", "Neurotransmitter degradation", "Neurotransmitter transport", "Nonsense-mediated mRNA decay", "Notch signaling pathway", "Nucleotide biosynthesis", "Nucleotide metabolism", "One-carbon metabolism", "Oogenesis", "Pentose shunt", "Peroxisome biogenesis", "Phagocytosis", "Phenylalanine catabolism", "Phospholipid biosynthesis", "Phospholipid metabolism", "Plasminogen activation", "Polyamine biosynthesis", "Porphyrin biosynthesis", "Potassium transport", "Proline biosynthesis", "Proline metabolism", "Prostaglandin biosynthesis", "Prostaglandin metabolism", "Protein biosynthesis", "Protein transport", "Purine biosynthesis", "Purine salvage", "Pyridine nucleotide biosynthesis", "Pyridoxine biosynthesis", "Pyrimidine biosynthesis", "RNA-mediated gene silencing", "Respiratory chain", "Ribosome biogenesis", "Sensory transduction", "Serine biosynthesis", "Sodium transport", "Sodium/potassium transport", "Spermatogenesis", "Spermidine biosynthesis", "Sphingolipid metabolism", "Steroid biosynthesis", "Steroid metabolism", "Sterol biosynthesis", "Sterol metabolism", "Stress response", "Sugar transport", "Symport", "Tetrahydrobiopterin biosynthesis", "Transcription", "Transcription regulation", "Transcription termination", "Translation regulation", "Translocation", "Transport", "Tricarboxylic acid cycle", "Tyrosine catabolism", "Ubl conjugation pathway", "Unfolded protein response", "Viral RNA replication", "Viral immunoevasion", "Viral penetration into host nucleus", "Virus entry into host cell", "Vision", "Wnt signaling pathway", "Xylose metabolism", "Zinc transport", "mRNA capping", "mRNA processing", "mRNA splicing", "mRNA transport", "rRNA processing", "tRNA processing"], "available_proteins": ["AAAS", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "ABCB1", "ABCB10", "ABCB7", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF3", "ABHD12", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACBD3", "ACIN1", "ACLY", "ACO2", "ACOT7", "ACOX1", "ACOX3", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN4", "ACTR3", "ADA", "ADAR", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFDN", "AGL", "AGPAT1", "AGPS", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AKAP17A", "AKAP8", "AKT1", "AKT2", "ALDH18A1", "ALDH3A2", "ALDH4A1", "ALDOA", "ALDOC", "ALKBH5", "ANAPC16", "ANAPC5", "ANAPC7", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANP32A", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP3B1", "AP3D1", "AP3M1", "APEX1", "API5", "APOL2", "APRT", "AQR", "ARCN1", "ARF4", "ARFGAP1", "ARFGAP2", "ARFIP2", "ARHGEF2", "ARHGEF7", "ARID1A", "ARIH1", "ARL2", "ARL3", "ARL6IP4", "ARL8B", "ARMT1", "ASAH1", "ASCC2", "ASCC3", "ASNA1", "ASNS", "ASPM", "ATAD5", "ATG3", "ATG4B", "ATIC", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7B", "ATRX", "AUP1", "BABAM1", "BABAM2", "BAG3", "BAG6", "BAK1", "BANF1", "BAX", "BAZ1A", "BAZ1B", "BCAP31", "BCAS2", "BCAT2", "BCCIP", "BCL10", "BCL2L12", "BCL2L13", "BCLAF1", "BET1", "BIRC6", "BMS1", "BNIP1", "BOP1", "BRD2", "BRIX1", "BSG", "BTF3", "BUB3", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C1QBP", "C2CD5", "CACUL1", "CACYBP", "CAD", "CAND1", "CANX", "CAPRIN1", "CARM1", "CARS", "CARS2", "CASP2", "CASP3", "CASP6", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC124", "CCDC86", "CCNB1", "CD2AP", "CD2BP2", "CD47", "CD81", "CDC123", "CDC23", "CDC27", "CDC42", "CDC45", "CDC5L", "CDC73", "CDCA8", "CDK1", "CDK13", "CDK2", "CDK4", "CDK5RAP3", "CDK6", "CDKAL1", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPV", "CEP55", "CERS2", "CFL1", "CGGBP1", "CHAF1A", "CHAF1B", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHEK2", "CHID1", "CHKA", "CHMP2A", "CHMP5", "CHMP7", "CHORDC1", "CHST14", "CIAPIN1", "CIRBP", "CISD2", "CKAP2", "CKAP5", "CLASP2", "CLCN3", "CLCN7", "CLIC1", "CLIC4", "CLINT1", "CLP1", "CLPTM1", "CLPTM1L", "CLSPN", "CLTA", "CLTC", "CMPK1", "CMTR1", "CNNM3", "CNOT1", "CNOT11", "CNOT7", "CNOT9", "COASY", "COG7", "COL4A3BP", "COMMD10", "COMMD2", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS6", "COPZ1", "COX2", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT2", "CRNKL1", "CS", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC22", "CXADR", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DCAF13", "DCAF7", "DCPS", "DCTN1", "DCTN3", "DCXR", "DDA1", "DDB1", "DDRGK1", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX46", "DDX47", "DDX5", "DDX51", "DDX54", "DDX56", "DENR", "DERL1", "DERL2", "DFFA", "DHCR24", "DHFR", "DHPS", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DICER1", "DIDO1", "DIP2B", "DIS3", "DIS3L2", "DKC1", "DLAT", "DLST", "DNAAF5", "DNAJA3", "DNAJB1", "DNAJC3", "DNM1", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOHH", "DPF2", "DPYSL2", "DSG2", "DST", "DTL", "DTYMK", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECH1", "ECHS1", "ECI1", "ECSIT", "EDF1", "EDRF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EHD1", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC4", "EMG1", "EML4", "ENO1", "ENOPH1", "ENSA", "ENY2", "EPB41", "EPB41L2", "EPB41L3", "EPHX1", "EPHX2", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERC1", "ERCC2", "ERCC6L", "ERGIC3", "ERH", "ERI1", "ERLIN2", "ERO1A", "ERP44", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EYA3", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAH", "FAM120B", "FAM162A", "FAM208A", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FBL", "FBXO22", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FIP1L1", "FKBP8", "FLII", "FLNA", "FLNB", "FLOT2", "FMR1", "FOXC1", "FOXRED1", "FRG1", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FXR1", "G3BP1", "G3BP2", "G6PD", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GBA", "GBF1", "GCC2", "GCFC2", "GCLM", "GCN1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GHITM", "GINS1", "GINS2", "GINS3", "GINS4", "GLTP", "GM2A", "GMPS", "GNAI1", "GNAI2", "GNAI3", "GNL2", "GNL3L", "GNPDA1", "GOLIM4", "GOPC", "GOT1", "GOT2", "GPAA1", "GPI", "GPKOW", "GRB2", "GRIPAP1", "GRSF1", "GRWD1", "GSPT1", "GSS", "GSTZ1", "GTF2E1", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C5", "GTPBP10", "GTPBP4", "GYG1", "GYS1", "H2AFX", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAUS4", "HAUS5", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HECTD1", "HELLS", "HERC2", "HGS", "HIBADH", "HIBCH", "HINT2", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCS1", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HPRT1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "ILF2", "ILF3", "ILVBL", "IMP3", "IMPDH2", "INA", "INCENP", "INTS3", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "IVD", "JUP", "KARS", "KAT7", "KCTD5", "KDELR1", "KDM1A", "KDM1B", "KDM3B", "KDSR", "KHDRBS1", "KHSRP", "KIF11", "KIF20A", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIFBP", "KLC1", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRR1", "LAMP1", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDAH", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LPCAT1", "LPGAT1", "LRPPRC", "LRWD1", "LSG1", "LSM14A", "LSM14B", "LSM2", "LSM6", "LSS", "LTA4H", "LTN1", "LUC7L3", "LYAR", "LYPLA1", "LZTS2", "M6PR", "MACF1", "MANF", "MAP1S", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARK2", "MARS", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MCAT", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MECP2", "MED17", "MED24", "MED25", "MESD", "METTL1", "MFN2", "MFSD10", "MFSD5", "MGEA5", "MGST2", "MIA3", "MICU1", "MID1", "MIF", "MINDY3", "MKI67", "MLEC", "MMGT1", "MMS19", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPG", "MPHOSPH10", "MPHOSPH6", "MRE11", "MRI1", "MRPL58", "MRPS27", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTFP1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR6", "MTOR", "MTPAP", "MTX1", "MTX2", "MTX3", "MVD", "MVK", "MYBBP1A", "MYDGF", "MYH10", "MYH9", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAE1", "NAMPT", "NAP1L1", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCAPH2", "NCBP1", "NCK1", "NCKAP1", "NCOA5", "NCSTN", "NDC1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF4", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4", "NEK9", "NELFA", "NELFCD", "NELFE", "NES", "NFS1", "NHP2", "NIP7", "NIPA2", "NKRF", "NLE1", "NLRX1", "NME1", "NME2", "NOC2L", "NOL11", "NOL8", "NOL9", "NONO", "NOP14", "NOP2", "NOP53", "NOP56", "NOP58", "NOSIP", "NPC1", "NPLOC4", "NPM1", "NPTN", "NSA2", "NSD2", "NSDHL", "NSF", "NSL1", "NSMCE2", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NUBP2", "NUCKS1", "NUDC", "NUDCD1", "NUDT21", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUTF2", "NVL", "NXF1", "NXN", "OCRL", "OGDH", "OGT", "OPA1", "OPA3", "ORC3", "OSBP", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OTULIN", "PA2G4", "PABPC1", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAK1IP1", "PAK2", "PANK4", "PAPOLA", "PARK7", "PARN", "PARP1", "PARP2", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCK2", "PCLAF", "PCM1", "PCNA", "PCNP", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDK3", "PDS5A", "PDS5B", "PECR", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFAS", "PFKL", "PFKM", "PFKP", "PGAM1", "PGAM5", "PGD", "PGK1", "PGM1", "PGM2", "PGM3", "PGP", "PHAX", "PHB", "PHB2", "PHF2", "PHF5A", "PHF6", "PHGDH", "PICALM", "PIGK", "PIGS", "PIGU", "PIH1D1", "PIK3C2A", "PIN1", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PKM", "PKMYT1", "PKN2", "PLA2G15", "PLBD2", "PLCG1", "PLD3", "PLIN3", "PLK1", "PLRG1", "PMVK", "PNN", "PNP", "PNPLA6", "PNPLA8", "PNPO", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLRMT", "POP1", "PPAT", "PPHLN1", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPM1F", "PPOX", "PPP1CA", "PPP1CB", "PPP2R1A", "PPP5C", "PPT1", "PQBP1", "PRAF2", "PRC1", "PRDX6", "PREB", "PRIM1", "PRIM2", "PRKAA1", "PRKAG1", "PRKDC", "PRKRA", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF39", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA3", "PSMA4", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC3", "PSMD10", "PSMD14", "PSME3", "PSME4", "PSPC1", "PTBP1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTK7", "PTRH2", "PUF60", "PUM1", "PURA", "PUS1", "PUS7", "PWP1", "PXN", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB21", "RAB24", "RAB35", "RAB39A", "RAB3B", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB8B", "RABGAP1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD51AP1", "RAE1", "RAI14", "RALY", "RAN", "RANBP2", "RANBP3", "RAPGEF2", "RARS", "RBBP5", "RBBP6", "RBM10", "RBM14", "RBM15", "RBM17", "RBM25", "RBM28", "RBM3", "RBM39", "RBM4", "RBM8A", "RBMX", "RBMXL1", "RBP1", "RCC1", "RCC2", "RCL1", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHOA", "RIF1", "RINT1", "RMDN3", "RNASET2", "RNF114", "RNF14", "RNF40", "RNMT", "RNPS1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPF2", "RPL10", "RPL13A", "RPP30", "RPRD1B", "RPS3", "RPS3A", "RPS6KA1", "RPS6KA3", "RPSA", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RTCB", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "SAE1", "SAFB", "SAFB2", "SAMHD1", "SAP18", "SAP30BP", "SAR1A", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCD", "SCFD1", "SCML2", "SCP2", "SCRIB", "SCRN1", "SDE2", "SDHA", "SDHB", "SEC16A", "SEC22B", "SEC23A", "SEC24A", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC63", "SEH1L", "SEL1L", "SENP3", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERPINH1", "SET", "SETD7", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN4", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SHMT1", "SHMT2", "SIGMAR1", "SIN3A", "SIRT1", "SIRT2", "SKIV2L2", "SKP1", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC30A5", "SLC35B2", "SLC35F2", "SLC3A2", "SLC9A3R1", "SLFN11", "SLIRP", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMS", "SMU1", "SNAP23", "SNAP29", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SOAT1", "SON", "SPC24", "SPC25", "SPECC1L", "SPEN", "SPOUT1", "SPTLC1", "SPTLC2", "SRCAP", "SREK1", "SRM", "SRPK1", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSBP1", "SSRP1", "STAG2", "STAM", "STAMBP", "STARD3", "STAT1", "STAT3", "STAU1", "STIM2", "STK4", "STMN1", "STRAP", "STRBP", "STUB1", "STX10", "STX12", "STX17", "STX18", "STX4", "STX5", "STX8", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SULT2A1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNGR2", "TACC3", "TACO1", "TALDO1", "TAMM41", "TARDBP", "TARS", "TARS2", "TBCB", "TCAF1", "TCEA1", "TCERG1", "TCF25", "TDP2", "TDRKH", "TECR", "TERF2IP", "TEX264", "TFAM", "TFG", "TFIP11", "TFRC", "THOC1", "THOC3", "THRAP3", "TIA1", "TIAL1", "TIMELESS", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TK1", "TLN1", "TMCO1", "TMED10", "TMED2", "TMED7", "TMEM109", "TMEM14C", "TMEM214", "TMX1", "TMX4", "TNPO1", "TNPO2", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOPBP1", "TP53", "TP53BP1", "TPI1", "TPR", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRIM21", "TRIM25", "TRIM27", "TRIM28", "TRIP12", "TRIP13", "TRMT10C", "TRMT11", "TRMT112", "TRMT6", "TROVE2", "TSC2", "TSFM", "TSG101", "TSNAX", "TSR1", "TTC19", "TTC26", "TTC4", "TTLL12", "TTYH3", "TUBB2B", "TUFM", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UBA1", "UBA2", "UBA3", "UBA6", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE2V1", "UBE3C", "UBE4A", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UCHL5", "UFC1", "UFD1", "UFL1", "UFSP2", "UGDH", "UHRF1", "UMPS", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USO1", "USP10", "USP11", "USP14", "USP19", "USP28", "USP33", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VPS13A", "VPS18", "VPS26A", "VPS29", "VPS33A", "VPS35", "VPS4A", "VPS51", "VPS53", "VRK1", "WAPL", "WARS", "WBP11", "WDR33", "WDR36", "WDR41", "WDR43", "WDR5", "WDR6", "WDR61", "WDR75", "WIPI2", "WRAP53", "WTAP", "XAB2", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YKT6", "YTHDC1", "YTHDC2", "YWHAB", "YWHAE", "ZC3H11A", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF638", "ZNF687", "ZPR1", "ZRANB2", "ZW10", "ZYX"], "leading_proteins": ["ABCB7", "ABCC1", "ABCC4", "AKT1", "AKT2", "ANKLE2", "ANLN", "AP1B1", "AP2A2", "ARFIP2", "ASPM", "ATG4B", "ATP5I", "ATP6", "ATP6V1B2", "BAG6", "CASP3", "CCNB1", "CDCA8", "CDS2", "CENPV", "CEP55", "CHKA", "CHMP7", "CKAP2", "CLPTM1L", "CNNM3", "COL4A3BP", "CTPS2", "CYB5B", "CYFIP1", "CYP51A1", "DAXX", "DCXR", "DERL1", "DHCR24", "DHX36", "DNAJA3", "DNAJC3", "DYNC1LI2", "EHD1", "ELMO2", "ENSA", "ERCC6L", "ERGIC3", "EXOC2", "EXOC4", "EXOC6", "EZR", "FABP5", "FDXR", "GABARAPL2", "GALM", "GCC2", "GLTP", "GNAI2", "GOLIM4", "GRIPAP1", "HINT2", "HMOX1", "HNRNPU", "IGF2BP2", "IPO11", "KIF23", "KIF2A", "KIF2C", "KMT2A", "KNTC1", "LCLAT1", "LETM1", "LIG1", "M6PR", "MANF", "MAP3K7", "MCU", "MFSD10", "MIA3", "MMGT1", "MOSPD2", "MTFP1", "MTX1", "MTX3", "MYH10", "MYH9", "NCAPD3", "NCAPG", "NDUFA11", "NDUFA5", "NDUFA8", "NDUFA9", "NDUFB11", "NDUFB3", "NDUFS2", "NDUFS3", "NECAP1", "NECAP2", "NUF2", "NUP188", "OCRL", "PAIP1", "PCBP2", "PDCD5", "PDK3", "PDS5B", "PHB", "PPM1F", "PPP1CA", "PRC1", "PSMD10", "PSME4", "PTRH2", "PYCR1", "QKI", "RAB5A", "RACGAP1", "RBP1", "RNF114", "RTN3", "SAP30BP", "SEPT6", "SFXN4", "SGPL1", "SIN3A", "SLC25A10", "SLC25A21", "SLC25A26", "SLC25A32", "SLC30A5", "SLC35B2", "SLC35F2", "SLC3A2", "SLTM", "SNAP29", "SNX1", "SPC25", "STAM", "STK4", "SUN1", "TDRKH", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TMEM109", "TMX4", "TOMM22", "TTC26", "TTYH3", "TWF2", "TXLNA", "TXNL1", "UBE2S", "UGDH", "UNC119", "UNC119B", "UQCR10", "UQCRB", "UQCRQ", "USP33", "VPS13A", "VPS18", "VPS26A", "VRK1", "WAPL", "XPO4", "YTHDC2"]} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/advanced/idx2term.json b/protein_atlas_disease_involvement/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/protein_atlas_disease_involvement/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/basic/idx2term.json b/protein_atlas_disease_involvement/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..ad79284bd69cda5e709ae62499ecad0b2896c64a --- /dev/null +++ b/protein_atlas_disease_involvement/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Cardiomyopathy", "1": "Primary mitochondrial disease", "2": "Deafness", "3": "Neuropathy", "4": "Cataract", "5": "Proto-oncogene", "6": "FDA approved drug targets"} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/basic/plot_0.png b/protein_atlas_disease_involvement/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..cba3b4ccbeb9b48576822994c54a1aeeac24566d --- /dev/null +++ b/protein_atlas_disease_involvement/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c220c2651b150f105f29ded60b7324e527012261290bc03dc19d4f2933e8cf26 +size 130881 diff --git a/protein_atlas_disease_involvement/basic/plot_1.png b/protein_atlas_disease_involvement/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..220e60b2d99efee2356056f579c0a07beb541776 --- /dev/null +++ b/protein_atlas_disease_involvement/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5772be68be23bd55af2ded1f33a1d7d7f44332a417be3183650e085bb76dc28b +size 146939 diff --git a/protein_atlas_disease_involvement/basic/plot_2.png b/protein_atlas_disease_involvement/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..e729dd001f49de1bf0c70994fcefb55ca8f08000 --- /dev/null +++ b/protein_atlas_disease_involvement/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:86138bb84e5c751fa25de325a7599c5495fa47b969f9154afa92ed73a9a1c6a1 +size 127924 diff --git a/protein_atlas_disease_involvement/basic/plot_3.png b/protein_atlas_disease_involvement/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..32c19743f822907713341b01af6ccb5feb21ebd5 --- /dev/null +++ b/protein_atlas_disease_involvement/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e093a23867ce68c3dabc2b0b2eb2c4170f9ae44c6b78ea2def868757f23a36ad +size 126904 diff --git a/protein_atlas_disease_involvement/basic/plot_4.png b/protein_atlas_disease_involvement/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..328a009807f059e4995b99b76eb0b97bcf37e69b --- /dev/null +++ b/protein_atlas_disease_involvement/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8ca89d28ceb2bab7243b9000cec7268f79405368f71d5b8f2d531036f6f3d5be +size 126393 diff --git a/protein_atlas_disease_involvement/basic/plot_5.png b/protein_atlas_disease_involvement/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..8f7fcc29565cc9ac11a8ef2801d633a813399ea5 --- /dev/null +++ b/protein_atlas_disease_involvement/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0e8562a8373efe1765649893dbd98a5665c2db8909eb0febf9df35bd3730e8d3 +size 138015 diff --git a/protein_atlas_disease_involvement/basic/plot_6.png b/protein_atlas_disease_involvement/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..db7442bbbeb32edce6e4628282d64fdc3c700005 --- /dev/null +++ b/protein_atlas_disease_involvement/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3d281eb76416689436d0e2d5a7a434bf48079240b3b815e1f262129aaedb90b2 +size 148721 diff --git a/protein_atlas_disease_involvement/consensus.joblib b/protein_atlas_disease_involvement/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..23b42b23f6b3c94c868b87f387b0cd79e4ac9d20 --- /dev/null +++ b/protein_atlas_disease_involvement/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d366076e92165f56aa1742363e76e9e93b8961580779a8f6d8a96feba84d65a3 +size 68621 diff --git a/protein_atlas_disease_involvement/df_merge.tsv b/protein_atlas_disease_involvement/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/protein_atlas_disease_involvement/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/protein_atlas_disease_involvement/metrics.json b/protein_atlas_disease_involvement/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..b153c78bcd2455199f2ed717bf1a61d8a67dd43a --- /dev/null +++ b/protein_atlas_disease_involvement/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2772, + "annotations_size": 109, + "title": "Average number of proteins per term", + "value": 20.073394495412845 +} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/paths.json b/protein_atlas_disease_involvement/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..e31585aae4493af3b850835cab52ddb5cd93226b --- /dev/null +++ b/protein_atlas_disease_involvement/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_disease_involvement/fragment/C321/C321_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/result.tsv b/protein_atlas_disease_involvement/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..16c56164cda648b2e6e8af15df7a2c107aaae9cb --- /dev/null +++ b/protein_atlas_disease_involvement/result.tsv @@ -0,0 +1,29 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Non-syndromic deafness 0.6193769452101366 1.8446545228711644 0.0650878102615273 0.9993483421486142 0.2867901455617095 14 P33527 1 +Cardiomyopathy 0.5439464258182144 1.7571626059187684 0.0788900970523251 0.9998711904062114 0.2867901455617095 23 P14923,P00846,P35609,Q9NX14,P15924 5 +Oncogene 0.7844765342960267 1.753374448565323 0.0795377539541704 0.9998806968733046 0.2867901455617095 2 O43663 1 +Primary mitochondrial disease 0.3902841775694532 1.6546619106210068 0.09799309747358 0.9999868817819938 0.3051785035605779 79 Q9Y276,Q5ST30,P14927,Q5JTZ9,Q9Y3D9,Q6P4A7,P00846,Q86Y39,Q9Y2R0,Q5XKP0,Q9BQT8,Q9NX14,Q9Y584,Q9UBX3,Q5JPH6,O14949,P13073,O75489,Q70HW3,O75306,Q8TB37,Q99797,O43676,Q9H0R6,Q9Y2Q9 25 +Deafness 0.4420190003958614 1.6224748929073527 0.1047017047129876 0.9999941858588004 0.3170134948254349 44 P68371,P21281,Q969T9,P22570,Q9Y276,Q15067,Q10567,Q9NSV4,O76024,Q13217,P33527,Q8N2K0 12 +Neuropathy 0.4373764967762274 1.5948127133121162 0.1107541232258415 0.9999972242346172 0.317689458726756 46 O95140,O00764,P22570,Q15067,Q12756,P07196,O95721,P04792,Q13217,P00846,Q71SY5,Q8N2K0 12 +Diabetes mellitus 0.696119671065455 1.5456427512186903 0.1221908703756728 0.9999993229664658 0.3415078172038037 8 Q13217,P40763,P31751 3 +Diamond-Blackfan anemia 0.5517365219413428 1.5261654679233625 0.1269686610546823 0.9999996265333072 0.3459896013740092 16 P18077,P62244,P61353,P42766 4 +Craniosynostosis 0.8820043875720358 1.508345692253394 0.1314660745836762 0.99999978730378 0.3495073690151392 4 O94761 1 +Charcot-Marie-Tooth disease 0.5043332713987714 1.4637240683837702 0.1432693565218563 0.9999999521338158 0.37181809192577 21 P04792,Q71SY5,O00764,P07196 4 +Cataract 0.4770562533794331 1.3556992322165673 0.1751948838184367 0.9999999992374 0.4082334561394282 25 Q01968,O94761,O76024,Q15800,Q5SRE5,Q8N2K0 6 +Kartagener syndrome 0.6844765342960255 1.290967060908195 0.1967150996080544 0.9999999999572649 0.4375907317811823 2 P57076 1 +Primary ciliary dyskinesia 0.6844765342960255 1.290967060908195 0.1967150996080544 0.9999999999572649 0.4375907317811823 2 P57076 1 +Limb-girdle muscular dystrophy 0.640559977296534 1.2058850652641018 0.227861809914438 0.9999999999994262 0.4599432829754397 7 Q7Z392,Q5JTV8,Q15149,O75190 4 +Retinitis pigmentosa 0.514095100997848 1.1495859456953412 0.2503144494747689 0.999999999999977 0.4872191962991037 13 P00846 1 +Bardet-Biedl syndrome 0.6480144404332091 1.1226222788606053 0.2615979492728826 0.9999999999999956 0.4932373587877016 2 Q9NQ48 1 +Spinocerebellar ataxia 0.5637699472702252 1.1168886075065592 0.264041956306758 0.9999999999999968 0.4932373587877016 10 O14773 1 +Proto-oncogene 0.3882628686895062 0.986225457336684 0.3240224895909409 1.0 0.5696524413776219 35 Q03164,P31749,Q06136,Q13951,Q96T37 5 +Palmoplantar keratoderma 0.5841648557726082 0.9665994840215444 0.3337442926453273 1.0 0.5774306015609632 7 Q06136,P14923,P15924 3 +FDA approved drug targets 0.3181895616422348 0.8736201876554475 0.3823251285549083 1.0 0.621991627052015 109 P68371,P21281,O00764,P49356,P54619,P49721,P00374,P22033,P23786,P33527,Q9UGN5,P20645,Q16850,P36507,P42574,Q07864 16 +Cushing syndrome 0.6688335139039304 0.6805898463655605 0.496131053467878 1.0 0.702855692902237 3 P17612,P10644 2 +Ichthyosis 0.4575683355881594 0.5212485536132223 0.6021936345820942 1.0 0.7632454205749798 8 P51648,O95721,Q10567 3 +Primary microcephaly 0.4382053109711483 0.4936787990239207 0.6215330403704169 1.0 0.7787023149468442 9 Q8IZT6 1 +Ciliopathy 0.3926311410076084 0.3276403980243698 0.7431835732402932 1.0 0.8617766966297016 9 P57076,Q01968 2 +Obesity 0.4643061201393835 0.1732137461450042 0.8624834190973842 1.0 0.9496029563799484 4 Q9C0B1 1 +Lissencephaly 0.3428067641369965 0.1399158179894567 0.8887265032796752 1.0 0.9497175378184765 7 Q9BSJ2,O00139 2 +Glutaricaciduria 0.4353323699422033 0.1261846480431912 0.899585763312545 1.0 0.9519888174860912 4 Q92947,P38117,P13804 3 +Parkinson disease 0.2703721232127537 0.0350019747477287 0.9720781662185858 1.0 0.9902478515684658 6 Q04637 1 diff --git a/protein_atlas_disease_involvement/selections.json b/protein_atlas_disease_involvement/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..8f28a1bf6db56d5dd51b3d3233b0c14da9a54b73 --- /dev/null +++ b/protein_atlas_disease_involvement/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Aicardi-Goutieres syndrome", "Albinism", "Allergen", "Alport syndrome", "Alzheimer disease", "Amyloidosis", "Amyotrophic lateral sclerosis", "Atrial fibrillation", "Autism", "Autism spectrum disorder", "Bardet-Biedl syndrome", "Bartter syndrome", "Cancer-related genes", "Cardiomyopathy", "Cataract", "Charcot-Marie-Tooth disease", "Ciliopathy", "Cockayne syndrome", "Cone-rod dystrophy", "Congenital adrenal hyperplasia", "Congenital disorder of glycosylation", "Congenital hypothyroidism", "Congenital muscular dystrophy", "Congenital myasthenic syndrome", "Craniosynostosis", "Cushing syndrome", "Deafness", "Diabetes insipidus", "Diabetes mellitus", "Diamond-Blackfan anemia", "Disease variant", "Dwarfism", "Dyskeratosis congenita", "Dystonia", "Dystroglycanopathy", "Ectodermal dysplasia", "Ehlers-Danlos syndrome", "Elliptocytosis", "Emery-Dreifuss muscular dystrophy", "Epidermolysis bullosa", "Epilepsy", "FDA approved drug targets", "Fanconi anemia", "Gangliosidosis", "Gaucher disease", "Glaucoma", "Glutaricaciduria", "Glycogen storage disease", "Gout", "Hereditary hemolytic anemia", "Hereditary nonpolyposis colorectal cancer", "Hereditary spastic paraplegia", "Hermansky-Pudlak syndrome", "Hirschsprung disease", "Holoprosencephaly", "Hypogonadotropic hypogonadism", "Hypotrichosis", "Ichthyosis", "Intrahepatic cholestasis", "Joubert syndrome", "Kallmann syndrome", "Kartagener syndrome", "Leber congenital amaurosis", "Leber hereditary optic neuropathy", "Leigh syndrome", "Leukodystrophy", "Li-Fraumeni syndrome", "Limb-girdle muscular dystrophy", "Lissencephaly", "Mental retardation", "Metachromatic leukodystrophy", "Microphthalmia", "Mucopolysaccharidosis", "Myofibrillar myopathy", "Nemaline myopathy", "Nephronophthisis", "Neurodegeneration", "Neuronal ceroid lipofuscinosis", "Neuropathy", "Niemann-Pick disease", "Non-syndromic deafness", "Obesity", "Oncogene", "Osteogenesis imperfecta", "Osteopetrosis", "Palmoplantar keratoderma", "Parkinson disease", "Parkinsonism", "Peroxisome biogenesis disorder", "Peters anomaly", "Phenylketonuria", "Premature ovarian failure", "Primary ciliary dyskinesia", "Primary hypomagnesemia", "Primary microcephaly", "Primary mitochondrial disease", "Progressive external ophthalmoplegia", "Proto-oncogene", "Pyropoikilocytosis", "Retinitis pigmentosa", "Rhizomelic chondrodysplasia punctata", "SCID", "Schizophrenia", "Spinocerebellar ataxia", "Systemic lupus erythematosus", "Tumor suppressor", "Williams-Beuren syndrome", "Xeroderma pigmentosum", "Zellweger syndrome"], "available_proteins": ["AAAS", "AARS", "AARS2", "ABCB1", "ABCB7", "ABCC1", "ABHD12", "ACAA1", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACLY", "ACO2", "ACOX1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ADA", "ADAR", "ADK", "ADNP", "ADPRHL2", "ADSL", "AFDN", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AKAP12", "AKR1B1", "AKT1", "AKT2", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ANK3", "ANKLE2", "ANLN", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA7", "AP1B1", "AP2B1", "AP2M1", "AP3B1", "AP3D1", "APEX1", "APOL2", "APRT", "ARCN1", "ARHGDIA", "ARHGEF2", "ARID1A", "ARIH1", "ARL2", "ARL3", "ARPC1B", "ASAH1", "ASNS", "ASPH", "ASPM", "ATAD1", "ATAD3A", "ATIC", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP6", "ATP6AP1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP7B", "ATRX", "ATXN10", "B4GAT1", "BAG3", "BANF1", "BAX", "BAZ1B", "BCAP31", "BCAT2", "BCL10", "BCLAF1", "BCS1L", "BIRC6", "BLMH", "BLVRB", "BMS1", "BRI3BP", "C19orf70", "C1QBP", "C21orf59", "CAD", "CALR", "CANX", "CAPN1", "CARM1", "CARS", "CARS2", "CASK", "CASP2", "CASP3", "CASP6", "CAST", "CBFB", "CCAR1", "CCAR2", "CCDC47", "CCDC6", "CCNB1", "CCT5", "CDC27", "CDC37", "CDC42", "CDC45", "CDC73", "CDK1", "CDK13", "CDK2", "CDK4", "CDK6", "CDKAL1", "CEP55", "CFL2", "CHAMP1", "CHD1", "CHD4", "CHEK2", "CHST14", "CISD2", "CIZ1", "CKB", "CKMT1A*", "CLCN7", "CLIC1", "CLN5", "CLP1", "CLPB", "CLPP", "CLPX", "CLTC", "CNOT1", "COA3", "COA7", "COASY", "COG7", "COL4A3BP", "COLGALT1", "COMT", "COPA", "COPB2", "COX2", "COX4I1", "COX5A", "CPOX", "CPSF1", "CPT2", "CRK", "CRTAP", "CSDE1", "CSE1L", "CSNK2A2", "CSNK2B", "CSTB", "CTBP1", "CTNNB1", "CTNNBL1", "CTNND1", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWF19L1", "CYB5R3", "CYC1", "CYP51A1", "DAD1", "DARS", "DARS2", "DAXX", "DBN1", "DCPS", "DCTN1", "DDOST", "DDRGK1", "DDX10", "DDX3X", "DDX41", "DDX5", "DDX6", "DEK", "DHCR24", "DHFR", "DHPS", "DHX16", "DHX30", "DHX37", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIS3", "DIS3L2", "DKC1", "DLD", "DLST", "DNAAF5", "DNAJB1", "DNAJB11", "DNAJB6", "DNAJC3", "DNM1", "DNM1L", "DNM2", "DNMT1", "DPF2", "DPM1", "DSG2", "DSP", "DST", "DYNC1H1", "DYNC1I2", "DYNLL1", "EARS2", "EBP", "ECE1", "ECHS1", "EDC3", "EEF1A2", "EEF2", "EFL1", "EFTUD2", "EHMT1", "EI24", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S2", "EIF3E", "EIF3F", "EIF3H", "EIF4A3", "EIF4E", "EIF4G1", "EIF4H", "EIF5A", "ELAC2", "ELP1", "ELP2", "ELP3", "EMC1", "EMD", "EMG1", "EML4", "ENO1", "EPB41", "EPB41L3", "EPHX1", "EPPK1", "EPRS", "ERAL1", "ERC1", "ERCC2", "ERLIN2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EZR", "FABP5", "FADS2", "FAF1", "FAH", "FAM120A", "FAM3C", "FANCD2", "FANCI", "FAR1", "FARSB", "FASN", "FDPS", "FDXR", "FECH", "FEN1", "FGFR1OP", "FH", "FHL1", "FIP1L1", "FKBP10", "FKBP14", "FKBP1A", "FKBP5", "FKBP8", "FLCN", "FLNA", "FLNB", "FLNC", "FMR1", "FNTA", "FNTB", "FOXC1", "FOXRED1", "FSCN1", "FTO", "FTSJ1", "FUBP1", "FUS", "G6PD", "GAA", "GALK1", "GALM", "GALNT2", "GANAB", "GAPDH", "GARS", "GART", "GATAD2B", "GBA", "GCDH", "GCLM", "GDI1", "GEMIN4", "GFM1", "GFPT1", "GGCX", "GIGYF2", "GINS1", "GLA", "GLB1", "GLDC", "GLMN", "GLO1", "GLRX5", "GLS", "GLUD1", "GM2A", "GMPPA", "GMPPB", "GMPS", "GNA13", "GNAI1", "GNAI3", "GNE", "GNS", "GOPC", "GOT1", "GOT2", "GPAA1", "GPI", "GPT2", "GRB2", "GSR", "GSS", "GSTM3", "GSTZ1", "GTF2I", "GUSB", "GYG1", "GYS1", "H4C1*", "HADH", "HADHA", "HADHB", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HELLS", "HERC2", "HEXA", "HEXB", "HIBCH", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLCS", "HMGA1", "HMGB3", "HMGCL", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HPRT1", "HPS6", "HSD17B10", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IFT27", "IGBP1", "IGF1R", "IGF2R", "ILF3", "IMPAD1", "IMPDH2", "INF2", "IPO7", "IRF2BPL", "IRS4", "ITGB1", "ITPA", "IVD", "JUP", "KARS", "KDM1A", "KDM3B", "KDSR", "KIF11", "KIF1A", "KIF22", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFBP", "KLC2", "KMT2A", "KTN1", "L2HGDH", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDHA", "LDHB", "LEMD3", "LGALS3", "LGALS3BP", "LIPA", "LMNA", "LMNB1", "LMNB2", "LONP1", "LRBA", "LRPPRC", "LSS", "LTA4H", "LZTFL1", "M6PR", "MACF1", "MAGED2", "MAP1B", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MARS", "MATR3", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM5", "MCM7", "MCTS1", "MDC1", "MDH1", "MDH2", "MECP2", "MED17", "MED25", "MESD", "MFN2", "MICU1", "MID1", "MIF", "MIPEP", "MKI67", "MMAB", "MOGS", "MPI", "MRE11", "MRPL12", "MRPL3", "MRPL44", "MRPS2", "MRPS22", "MRPS23", "MRPS28", "MRPS34", "MRPS7", "MSH2", "MSH6", "MSMO1", "MSN", "MSTO1", "MTA1", "MTOR", "MTPAP", "MUT", "MVD", "MVK", "MYH10", "MYH9", "MYO6", "NAA10", "NAA15", "NAGLU", "NAMPT", "NANS", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPH", "NCSTN", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA6", "NDUFA9", "NDUFAF4", "NDUFB11", "NDUFB3", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NEFL", "NEK9", "NHLRC2", "NHP2", "NME1", "NME2", "NNT", "NONO", "NOP56", "NPC1", "NPM1", "NSD2", "NSDHL", "NSMCE2", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NUBPL", "NUCB2", "NUDT1", "NUMA1", "NUP107", "NUP133", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP37", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXN", "OAT", "OCRL", "OGDH", "OGT", "OPA1", "OPA3", "OSGEP", "OTULIN", "P3H1", "P4HB", "PABPC1", "PABPN1", "PAF1", "PAFAH1B1", "PAFAH1B2", "PARK7", "PARN", "PARP1", "PARP2", "PBRM1", "PC", "PCBD1", "PCBP1", "PCCA", "PCCB", "PCM1", "PCNA", "PDCD4", "PDE6D", "PDHA1", "PDHB", "PDK3", "PDXK", "PEPD", "PEX14", "PEX19", "PEX5", "PFKM", "PFN1", "PGK1", "PGM1", "PGM3", "PHB", "PHF6", "PHGDH", "PHIP", "PICALM", "PIGK", "PIGS", "PIGU", "PIK3C2A", "PIN1", "PINX1", "PISD", "PKM", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMVK", "PNN", "PNP", "PNPLA6", "PNPO", "PNPT1", "POGZ", "POLA1", "POLD1", "POLE", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR3A", "POP1", "POR", "PPA2", "PPIB", "PPIF", "PPOX", "PPP1CB", "PPP2R1A", "PPP2R5D", "PPP3CA", "PPP5C", "PPT1", "PQBP1", "PRC1", "PRDX2", "PRDX4", "PRDX5", "PREPL", "PRKAA1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKCSH", "PRKDC", "PRKRA", "PRPF3", "PRPF31", "PRPF4", "PRPF6", "PRPF8", "PSAP", "PSAT1", "PSIP1", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMD12", "PSMD4", "PTDSS1", "PTPN11", "PTRH2", "PUF60", "PUM1", "PURA", "PUS1", "PUS7", "PYCR1", "PYCR2", "PYGL", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "RAB10", "RAB18", "RAB3GAP2", "RAB7A", "RAB8A", "RAC1", "RAD21", "RAD23B", "RANBP2", "RANBP3", "RAP1GDS1", "RAPGEF2", "RARS", "RASA1", "RBM10", "RBM12", "RBM15", "RBM28", "RBMX", "RDH11", "RDX", "RECQL4", "RFC1", "RFC2", "RHOA", "RINT1", "RNASEH2A", "RNASEH2B", "RNASET2", "ROCK2", "RP2", "RPA2", "RPL10", "RPL11", "RPL13", "RPL15", "RPL18", "RPL21", "RPL22", "RPL26", "RPL27", "RPL3", "RPL35", "RPL35A", "RPL5", "RPN1", "RPS10", "RPS15", "RPS15A", "RPS17", "RPS19", "RPS2", "RPS23", "RPS24", "RPS26", "RPS28", "RPS3", "RPS6KA1", "RPS6KA3", "RPS7", "RPSA", "RRM1", "RRM2", "RTN2", "RTN4IP1", "SAMHD1", "SARS", "SART1", "SBDS", "SC5D", "SCARB2", "SCO1", "SCO2", "SCRIB", "SDHA", "SDHB", "SEC23A", "SEC31A", "SEC61A1", "SEC63", "SEPT2", "SEPT9", "SERPINB6", "SERPINH1", "SET", "SF3B1", "SFPQ", "SFXN4", "SGPL1", "SH3GL1", "SHOC2", "SIGMAR1", "SIN3A", "SIRT2", "SKIV2L", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC3A2", "SLC9A3R1", "SMARCA4", "SMARCAD1", "SMARCB1", "SMARCC2", "SMARCE1", "SMC1A", "SMC3", "SMCHD1", "SMN1*", "SMPD4", "SMS", "SMYD3", "SNAP29", "SND1", "SNRNP200", "SNRPE", "SNX3", "SOAT1", "SOD2", "SON", "SORD", "SPART", "SPECC1L", "SPEN", "SPR", "SPTAN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRP54", "SRP72", "SRSF3", "SSB", "SSR4", "STAG2", "STAMBP", "STARD3", "STAT1", "STAT3", "STMN1", "STRAP", "STRN", "STT3A", "STT3B", "STUB1", "STX5", "SUCLA2", "SUCLG1", "SUZ12", "SV2A", "SYNE2", "TACO1", "TAF15", "TALDO1", "TARDBP", "TARS", "TARS2", "TBC1D4", "TBCD", "TBCE", "TBL2", "TCEA1", "TCOF1", "TDP2", "TECR", "TELO2", "TFAM", "TFG", "TFRC", "TIA1", "TIMM17A", "TIMM22", "TIMM50", "TK1", "TKT", "TMCO1", "TMEM199", "TMEM230", "TMEM43", "TMTC3", "TMX2", "TOE1", "TOP1", "TOP2A", "TOP2B", "TOR1AIP1", "TP53", "TP53BP1", "TPD52", "TPI1", "TPM3", "TPM4", "TPP1", "TPR", "TPX2", "TRAPPC11", "TRIM25", "TRIM27", "TRIP12", "TRIP13", "TRMT10C", "TSC2", "TSFM", "TSG101", "TTC19", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUFM", "TWF1", "TWNK", "TXLNA", "TXNRD1", "TYMS", "U2AF1", "UBA1", "UBE2N", "UBR5", "UBTF", "UFC1", "UFSP2", "UGDH", "UGP2", "UMPS", "UNC119", "UNG", "UPF3B", "UQCRB", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USMG5", "USP9X", "UTP4", "VAC14", "VAPB", "VARS1", "VARS2", "VCL", "VCP", "VIM", "VPS13A", "VPS33A", "VPS35", "VPS4A", "VPS51", "VPS53", "VRK1", "WARS", "WBP2", "WDR1", "WDR36", "WDR5", "WDR73", "WFS1", "WIPI2", "WRAP53", "XPNPEP3", "XPO1", "XRCC1", "XRCC5", "XRCC6", "YARS", "YARS2", "YBX1", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAZ", "ZC3H14", "ZCCHC8", "ZMPSTE24"], "leading_proteins": ["AARS2", "ABCC1", "ABHD12", "ACOX1", "ACTN2", "AKT1", "AKT2", "ALDH3A2", "AP1B1", "ASPM", "ATP6", "ATP6V1B2", "BCS1L", "C19orf70", "C21orf59", "CASP3", "CBFB", "COA3", "COX4I1", "CPT2", "CYP51A1", "DHFR", "DIAPH3", "DNAJB6", "DNAJC3", "DSP", "EARS2", "EIF4G1", "ETFA", "ETFB", "FDXR", "FNTB", "FTO", "GCDH", "HSPB1", "JUP", "KDSR", "KIF1A", "KIF2A", "KMT2A", "LZTFL1", "M6PR", "MAP2K2", "MED25", "MFN2", "MIPEP", "MRPS23", "MRPS28", "MSMO1", "MUT", "NDUFA11", "NDUFB11", "NDUFB3", "NDUFS2", "NDUFS3", "NEFL", "NUBPL", "NUP188", "OCRL", "PARP2", "PDXK", "PLEC", "POLE", "PRC1", "PRKACA", "PRKAG1", "PRKAR1A", "PSMB2", "QRSL1", "RBM15", "RECQL4", "RPL27", "RPL35", "RPL35A", "RPS15A", "SFXN4", "SLC25A10", "SLC25A21", "SLC25A26", "SNAP29", "STAT3", "TIMM22", "TOR1AIP1", "TPP1", "TRAPPC11", "TUBB4B", "TUBGCP2", "UQCRB", "UQCRQ", "VARS2", "WBP2", "WFS1"]} \ No newline at end of file diff --git a/protein_atlas_molecular_function/advanced/idx2term.json b/protein_atlas_molecular_function/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/protein_atlas_molecular_function/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/protein_atlas_molecular_function/basic/idx2term.json b/protein_atlas_molecular_function/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..8e2aa458f506e12d184fb295ce07003cf94b2ae8 --- /dev/null +++ b/protein_atlas_molecular_function/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Ribosomal protein", "1": "Glycosyltransferase", "2": "Serine/threonine-protein kinase", "3": "Chaperone", "4": "Protease", "5": "Kinase", "6": "Developmental protein", "7": "Initiation factor", "8": "Chromatin regulator"} \ No newline at end of file diff --git a/protein_atlas_molecular_function/basic/plot_0.png b/protein_atlas_molecular_function/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..55560085014c6aaf30579c40f424563fc2f1dbf4 --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:62723be10c34cf96dd43d425a2710f5dcf6674d51635a9ced6fa0c2658f78897 +size 138960 diff --git a/protein_atlas_molecular_function/basic/plot_1.png b/protein_atlas_molecular_function/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..3d131a2eee7eab63dc0dda8848666d49731ff586 --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:81f5c2253c34fa77cfa828eeae48305500a324ddf6d3e8179a988bf8b8c050c6 +size 145260 diff --git a/protein_atlas_molecular_function/basic/plot_2.png b/protein_atlas_molecular_function/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..9d11572253e9fc2e5cd17418d0c9adaeb224acb1 --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:63791557da43715ddb04cf570875866a4d917cf769e5e74044aec144a0f7e4f0 +size 139955 diff --git a/protein_atlas_molecular_function/basic/plot_3.png b/protein_atlas_molecular_function/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..f9f2820049d0ccead657c8e3c1780c31bd344514 --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d9b592398f013c826299ceda90431629ee2d01a3cdfadf677b107cdcaf6376c0 +size 140004 diff --git a/protein_atlas_molecular_function/basic/plot_4.png b/protein_atlas_molecular_function/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..78d274cb51f3580ba7777c8b56ec5dfeb8c3f591 --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:302699bf935f3554348102c85c68f21cedc3db469f45378a35884c1707576c45 +size 141411 diff --git a/protein_atlas_molecular_function/basic/plot_5.png b/protein_atlas_molecular_function/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..5cf8eeb1be2041e76c827395c177dc379518387a --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:199528b95705a5ebca10fb20401ca874ab01b3acbfee58e6ae742a2bdb19daf0 +size 137274 diff --git a/protein_atlas_molecular_function/basic/plot_6.png b/protein_atlas_molecular_function/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..f1174346ebf02b5e4a1972bdee1ba553840e8e20 --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ecdd5a2ad822d4fa23b06881f77529cd2628c0ff39fa4711bb11c3a17fd1c8ce +size 142143 diff --git a/protein_atlas_molecular_function/basic/plot_7.png b/protein_atlas_molecular_function/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..38eacb20cf3563e1708f408ad83d1b573af079b9 --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:78a8dbce7752fb855bc18e109ec9ca4faa7a4afba68079b3f53e4a159b4c66b9 +size 147599 diff --git a/protein_atlas_molecular_function/basic/plot_8.png b/protein_atlas_molecular_function/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..46a752994d1e3e87c26d6b35465f28e9784f3a3d --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:954822d60cab1236e5f7500f0f67ceaec568d997c08eda9fdaa0f7096523cb33 +size 145576 diff --git a/protein_atlas_molecular_function/consensus.joblib b/protein_atlas_molecular_function/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..386c4d946e37b6a297105fa30be8e31fabede9dd --- /dev/null +++ b/protein_atlas_molecular_function/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ff0418736291431b05937c6bc9c47a41f7fa5da85ede1fe0e5d86cf863af15ad +size 69232 diff --git a/protein_atlas_molecular_function/df_merge.tsv b/protein_atlas_molecular_function/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/protein_atlas_molecular_function/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/protein_atlas_molecular_function/metrics.json b/protein_atlas_molecular_function/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..bf117a0be341682ce7622f33b0f3649d077aed55 --- /dev/null +++ b/protein_atlas_molecular_function/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2772, + "annotations_size": 95, + "title": "Average number of proteins per term", + "value": 34.85263157894737 +} \ No newline at end of file diff --git a/protein_atlas_molecular_function/paths.json b/protein_atlas_molecular_function/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..ae542aedc07590b1359bfcac5938f621df569420 --- /dev/null +++ b/protein_atlas_molecular_function/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_molecular_function/fragment/C321/C321_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_molecular_function/result.tsv b/protein_atlas_molecular_function/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..7e4b9ffef1b4dd4a320a8b254a632779a3822b30 --- /dev/null +++ b/protein_atlas_molecular_function/result.tsv @@ -0,0 +1,30 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Ion channel 0.7544122936835067 1.5856498971561537 0.1128187506076534 0.9999884873932866 0.4339930232588761 6 Q9C0H2,Q8NE86 2 +Ribosomal protein 0.3662411918675951 1.5449754722282731 0.1223521963144009 0.9999958749835688 0.4339930232588761 113 P62906,Q96DV4,P47914,Q9Y3D9,P18077,Q6P1L8,P52815,P62249,P62910,Q9Y3U8,P62899,Q9Y2R5,P62753,P62424,P82664,P49406,P62841,Q9NRX2,P32969,P63173,P62263,P62081,P15880,P30050,Q92552,Q96EY7,P82673,P62241,Q9H9J2,Q13084,Q8N5N7,P35268,P82675,P62244,P62829,P62269,Q9BYD2,P39019,Q14197,P62750,P61247,Q8TAE8,P08865,Q9NQ50,P62277,P05388,P46781,P61353,P42766,P18124,P26373,Q9Y2Q9,P05387 53 +Monooxygenase 0.9023166445725844 1.522380638979571 0.1279137331710371 0.9999977449949852 0.4339930232588761 3 Q6UW02 1 +Methyltransferase 0.4154683325277623 1.3656480869849486 0.1720494456562729 0.9999999837662774 0.518319832173569 39 P22061,Q7L592,Q03164 3 +Translocase 0.4827718746668072 1.338165723571593 0.1808424198902862 0.9999999941128084 0.518319832173569 22 O75489,P33527 2 +Receptor 0.4478679436255621 1.2762364857237345 0.2018719346360216 0.9999999995023828 0.518319832173569 30 O15173,Q9NS69,Q8WTV0,P20645 4 +Rotamase 0.4595764948617976 1.174387879506886 0.2402396978313641 0.999999999995384 0.5653590910339864 21 Q9Y3C6,Q9Y680,Q9Y237,O95302 4 +Glycosyltransferase 0.4250597040735376 1.040267118710194 0.2982158161472124 0.9999999999999976 0.6446862795409727 27 Q8TCJ2,O60762,Q9UGN5,P43490,O15294,Q9NYU2 6 +Serine/threonine-protein kinase 0.3718683701379481 0.9840687574703306 0.325081707107643 1.0 0.6713643951136107 42 O43318,O95747,Q14004,P31749,Q7KZI7,P31751,Q99640,P36507,Q13043 9 +Acyltransferase 0.4059767256142713 0.9259427059172446 0.3544757560063751 1.0 0.6915866645534785 28 Q8IUH4 1 +Nucleotidyltransferase 0.4062045839966068 0.8325538914604074 0.405096372478861 1.0 0.7545912820684666 21 O95674,Q13057,Q07864 3 +Serine protease inhibitor 0.5768953068592009 0.8026485697957111 0.4221778869479053 1.0 0.7625087557937816 2 P35237 1 +Metalloprotease 0.3794472696834665 0.7267764080862018 0.467362937534892 1.0 0.8222125752928655 27 O75844,O00487,Q9NZ08 3 +Chaperone 0.3012918967116498 0.6766154498260449 0.4986499739708288 1.0 0.8374906158753728 97 O75832,Q9BS26,Q9Y276,Q9Y5L4,O75190,P04792,Q9BT73,Q13217,Q96A33,P46379,O95429,Q9UER7,O95456,Q96EY1 14 +Transducer 0.4469524925800032 0.5282135202423645 0.5973511464376748 1.0 0.8734783435226872 9 P04899 1 +Protease 0.2885997775923335 0.4875670982458005 0.6258565051839509 1.0 0.8734783435226872 80 O75844,Q92643,Q8TEY7,O00487,P28072,Q9NZ08,Q8TCT8,Q96TA2,P42785,P81605,O00303,Q13867,P42574,Q9Y4P1,O14773 15 +Aminotransferase 0.4419633511016709 0.4626494999464207 0.6436156215430326 1.0 0.8734783435226872 8 P17174,Q8TD30,O15382 3 +rRNA-binding 0.3603712076630115 0.4467406511333429 0.6550623270487539 1.0 0.8764918460511496 15 Q9Y2R5,P62750,O75616,P62269 4 +Host cell receptor for virus entry 0.3539785403225629 0.4166449103536365 0.6769381548097202 1.0 0.8931822875961586 15 Q8WTV0 1 +Kinase 0.2604558039889995 0.2666040183527607 0.7897740613940467 1.0 0.9619043055440312 85 Q13057,O00764,O95747,O43318,Q14004,P31749,Q7KZI7,P35790,P31751,Q99640,P36507,Q13043 12 +Protease inhibitor 0.4022406938922935 0.2307774605659487 0.8174876924801184 1.0 0.9752888645529718 5 Q9NR09,P30086,P04080,P35237 4 +Developmental protein 0.263080163292068 0.1699433391737001 0.8650546970930812 1.0 1.0 63 O00139,P31749,Q7KZI7,Q9H2U1,Q53EZ4,Q96PU8,P31751,Q6UWP7,Q9H0H5,Q9Y508,Q00839,Q9Y6E2,P16949,Q14997 14 +tRNA-binding 0.2752942957113927 0.1211392538215271 0.9035807380500523 1.0 1.0 16 P18077,O43592,Q7Z4G4,Q5JTZ9 4 +Thiol protease inhibitor 0.4019501625135457 0.0717621371397681 0.9427912052844958 1.0 1.0 3 P04080,Q9NR09 2 +Ligase 0.2446681990172807 0.0657427196417226 0.9475826606053016 1.0 1.0 65 P18858,Q9HCC0,Q8TBC4 3 +Peroxidase 0.2338272497289486 0.0194308614332898 0.9844973911887174 1.0 1.0 5 P30041,P30044,P30048,P32119 4 +Antioxidant 0.2338272497289486 0.0194308614332898 0.9844973911887174 1.0 1.0 5 P30041,P30044,P30048,P32119 4 +Initiation factor 0.2316424256508999 0.0082420472235107 0.9934238722252348 1.0 1.0 35 O00303,Q04637,Q14152,Q7L2H7,P46199,O43583,Q9ULC4,Q7Z478 8 +Chromatin regulator 0.2314027787012342 2.6583957570811618e-05 0.9999787890706916 1.0 1.0 65 Q03164,Q14527,O15294,P46379,P46100,P28370,Q9UER7,Q9P0M6 8 diff --git a/protein_atlas_molecular_function/selections.json b/protein_atlas_molecular_function/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..92a0f649cc1f3a3dcc62c97e3a61c85bbe1ed5d9 --- /dev/null +++ b/protein_atlas_molecular_function/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin capping", "Actin-binding", "Activator", "Acyltransferase", "Allosteric enzyme", "Aminoacyl-tRNA synthetase", "Aminopeptidase", "Aminotransferase", "Antibiotic", "Antimicrobial", "Antioxidant", "Aspartyl protease", "Blood group antigen", "Calcium channel", "Calmodulin-binding", "Carboxypeptidase", "Chaperone", "Chloride channel", "Chromatin regulator", "Cyclin", "Cytokine", "DNA-binding", "DNA-directed DNA polymerase", "Decarboxylase", "Developmental protein", "Dioxygenase", "Dipeptidase", "Elongation factor", "Endonuclease", "Excision nuclease", "Exonuclease", "Fungicide", "GTPase activation", "Glycosidase", "Glycosyltransferase", "Growth factor", "Guanine-nucleotide releasing factor", "Helicase", "Heparin-binding", "Hormone", "Host cell receptor for virus entry", "Hydrolase", "IgE-binding protein", "Initiation factor", "Integrin", "Ion channel", "Isomerase", "Kinase", "Ligase", "Lyase", "Metalloenzyme inhibitor", "Metalloprotease", "Methyltransferase", "Mitogen", "Monooxygenase", "Motor protein", "Multifunctional enzyme", "Muscle protein", "Myosin", "Nuclease", "Nucleotidyltransferase", "Oxidoreductase", "Peroxidase", "Phospholipase A2 inhibitor", "Porin", "Prenyltransferase", "Protease", "Protease inhibitor", "Protein phosphatase", "Protein phosphatase inhibitor", "Protein synthesis inhibitor", "RNA-binding", "Receptor", "Repressor", "Ribonucleoprotein", "Ribosomal protein", "Rotamase", "Serine esterase", "Serine protease", "Serine protease inhibitor", "Serine/threonine-protein kinase", "Signal transduction inhibitor", "Thiol protease", "Thiol protease inhibitor", "Threonine protease", "Topoisomerase", "Transducer", "Transferase", "Translational shunt", "Translocase", "Tumor antigen", "Tyrosine-protein kinase", "Voltage-gated channel", "rRNA-binding", "tRNA-binding"], "available_proteins": ["AAMP", "AARS", "AARS2", "AASDHPPT", "AASS", "ABCB1", "ABCC1", "ABCC4", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAP2", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADH5", "ADI1", "ADK", "ADNP", "ADO", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPS", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP17A", "AKAP8", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALKBH5", "ANKHD1", "ANKRD17", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA2", "APEH", "APEX1", "APRT", "AQR", "ARFGAP1", "ARFGAP2", "ARHGAP1", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARIH1", "ARL8B", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "AS3MT", "ASAH1", "ASCC3", "ASNA1", "ASNS", "ASPH", "ASPM", "ASRGL1", "ATAD1", "ATG3", "ATG4B", "ATIC", "ATL2", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5B", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "ATP7B", "ATRX", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BANF1", "BAP18", "BAZ1B", "BCAT2", "BCLAF1", "BCS1L", "BIRC6", "BLMH", "BLVRA", "BLVRB", "BPNT1", "BRD2", "BSG", "BTF3", "BZW1", "BZW2", "C12orf43", "CAD", "CALD1", "CALR", "CANX", "CAP1", "CAPN1", "CAPRIN1", "CAPZA1", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP2", "CASP3", "CASP6", "CAST", "CBR1", "CBX3", "CCAR1", "CCAR2", "CCDC47", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD81", "CDC37", "CDC42", "CDC5L", "CDK1", "CDK13", "CDK2", "CDK4", "CDK6", "CDKAL1", "CDKN2AIP", "CDS2", "CEBPZ", "CELF1", "CELF2", "CEP55", "CERS2", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHEK2", "CHKA", "CHORDC1", "CHRAC1", "CHST14", "CHUK", "CIRBP", "CKB", "CKMT1A*", "CLGN", "CLIC1", "CLIC4", "CLP1", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLSPN", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT7", "CNOT9", "CNP", "COASY", "COLGALT1", "COMT", "COPA", "COPS5", "CORO1C", "COTL1", "COX2", "COX4I1", "CPD", "CPNE1", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT2", "CPVL", "CRYZL1", "CS", "CSDE1", "CSK", "CSNK1A1", "CSNK2A2", "CSTB", "CSTF2", "CTBP1", "CTBP2", "CTNNB1", "CTPS1", "CTPS2", "CTSA", "CTSB", "CTSC", "CUL5", "CXADR", "CXorf57", "CYB5R3", "CYC1", "CYFIP1", "CYP20A1", "CYP51A1", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DCAF13", "DCAF7", "DCD", "DCPS", "DCTPP1", "DCXR", "DDB1", "DDI2", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENR", "DGCR8", "DHCR24", "DHFR", "DHPS", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX40", "DHX8", "DHX9", "DIAPH1", "DICER1", "DIEXF", "DIS3", "DIS3L2", "DKC1", "DLAT", "DLD", "DLST", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOHH", "DPF2", "DPH2", "DPM1", "DPP3", "DPP9", "DPYSL2", "DRG1", "DRG2", "DST", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "EARS2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC3", "EDF1", "EDRF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EFL1", "EHMT1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMOD2", "ELP3", "EMD", "EMG1", "ENDOD1", "ENO1", "ENOPH1", "ENSA", "ENY2", "EPB41", "EPB41L2", "EPB41L3", "EPHX1", "EPHX2", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERCC2", "ERCC6L", "ERI1", "ERMP1", "ERO1A", "ERP44", "ESD", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EYA3", "F11R", "FADS2", "FAH", "FAHD1", "FAHD2A", "FAM120A", "FAM120B", "FAM208A", "FAM3C", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FLCN", "FLII", "FLNA", "FLNB", "FLNC", "FMR1", "FN3KRP", "FNTA", "FNTB", "FOXC1", "FOXRED1", "FRG1", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GBA", "GBF1", "GCAT", "GCDH", "GCN1", "GDI1", "GDI2", "GDPD1", "GEMIN5", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GLA", "GLB1", "GLDC", "GLO1", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPB", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNE", "GNG12", "GNG5", "GNPDA1", "GNS", "GOT1", "GOT2", "GPD2", "GPI", "GPKOW", "GPT2", "GRHPR", "GRPEL1", "GRSF1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C5", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDLBP", "HEATR1", "HECTD1", "HELLS", "HELZ", "HERC2", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLCS", "HLTF", "HM13", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HP1BP3", "HPRT1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HTATSF1", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDI1", "IFIT5", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "ILF2", "ILF3", "ILKAP", "ILVBL", "IMP3", "IMPAD1", "IMPDH2", "INA", "INF2", "IQGAP1", "IRF2BPL", "IRS4", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPK1", "IVD", "KARS", "KAT7", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM3B", "KDSR", "KHDRBS1", "KHSRP", "KIF11", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KLC1", "KLC2", "KLC4", "KMT2A", "KRR1", "KYAT3", "L2HGDH", "LAMP1", "LANCL1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LBR", "LCLAT1", "LDAH", "LDHA", "LDHB", "LEMD3", "LGALS3", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LNPEP", "LONP1", "LPCAT1", "LPGAT1", "LRPAP1", "LRPPRC", "LRWD1", "LSG1", "LSM14A", "LSM14B", "LSM2", "LSM6", "LSS", "LTA4H", "LTN1", "LUC7L3", "LYAR", "LYPLA1", "M6PR", "MACF1", "MAGED2", "MANF", "MAP1S", "MAP2K1", "MAP2K2", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MARC1", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MAT2A", "MATR3", "MCAT", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED17", "MED24", "MED25", "MEPCE", "MESD", "METTL1", "METTL13", "MFN2", "MGEA5", "MGST2", "MGST3", "MID1", "MIF", "MINDY3", "MIPEP", "MKI67", "MMAB", "MMS19", "MOGS", "MORF4L1", "MORF4L2", "MOV10", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPRIP", "MPST", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL44", "MRPL46", "MRPL50", "MRPL58", "MRPL9", "MRPS10", "MRPS15", "MRPS17", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MSH2", "MSH3", "MSH6", "MSMO1", "MTA1", "MTA2", "MTAP", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR6", "MTOR", "MTPAP", "MUT", "MVD", "MVK", "MYBBP1A", "MYG1", "MYH10", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA40", "NAA50", "NADK2", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L4", "NARS", "NAT10", "NAXE", "NCL", "NCOA5", "NDUFAF4", "NDUFAF7", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NEDD4", "NEK9", "NELFA", "NELFCD", "NELFE", "NES", "NFS1", "NHP2", "NIFK", "NIP7", "NKRF", "NKTR", "NLN", "NME1", "NME2", "NMT1", "NNT", "NOC2L", "NOL11", "NOL6", "NOL8", "NOL9", "NONO", "NOP2", "NOP56", "NOP58", "NOSIP", "NOVA2", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NRDC", "NSA2", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSUN2", "NSUN5", "NSUN6", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDCD1", "NUDT1", "NUDT12", "NUDT16L1", "NUDT21", "NUDT5", "NUFIP2", "NUP153", "NUP98", "NXF1", "NXN", "OAT", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC3", "OSGEP", "OTUB1", "OTUD4", "OTULIN", "OXSR1", "P3H1", "P4HA1", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAK1IP1", "PAK2", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PASK", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PCYOX1", "PDCD4", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK3", "PDXDC1", "PDXK", "PEBP1", "PECR", "PELP1", "PEPD", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB2", "PHF2", "PHF5A", "PHF6", "PHGDH", "PI4K2A", "PIGK", "PIK3C2A", "PIN1", "PIN4", "PIR", "PISD", "PITHD1", "PITRM1", "PKM", "PKMYT1", "PKN2", "PLA2G15", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PMPCB", "PMVK", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPO", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLDIP3", "POLE", "POLE4", "POLR1A", "POLR1B", "POLR2B", "POLR2G", "POLR3A", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAT", "PPHLN1", "PPIB", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP3CA", "PPP4C", "PPP5C", "PPT1", "PPT2", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKACA", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF31", "PRPF4B", "PRPF8", "PSAT1", "PSIP1", "PSMB5", "PSMB6", "PSMB7", "PSMD10", "PSMD14", "PSME4", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTRH2", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "RAB10", "RAB18", "RAB1A", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD50", "RAD51AP1", "RALY", "RANBP1", "RANBP2", "RANGAP1", "RAP1GDS1", "RAPGEF2", "RARS", "RASA1", "RAVER1", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM8A", "RBMX", "RBMXL1", "RCC1", "RCC2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC3", "RHOA", "RHOT1", "RHOT2", "RIDA", "RNASEH2A", "RNASET2", "RNF114", "RNF14", "RNF40", "RNMT", "RNPEP", "RNPS1", "ROCK2", "RP2", "RPA1", "RPA2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPP30", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RREB1", "RRM1", "RRM2", "RRP1B", "RRP8", "RRP9", "RSBN1", "RSF1", "RTCB", "RTRAF", "RUVBL1", "RUVBL2", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMHD1", "SAP18", "SAP30BP", "SARNP", "SARS", "SARS2", "SART3", "SC5D", "SCAF1", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SDE2", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC61A1", "SEC63", "SENP3", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD7", "SF1", "SF3B1", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SGPL1", "SGTA", "SHMT1", "SHMT2", "SHTN1", "SIGMAR1", "SIN3A", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SLC1A5", "SLC27A4", "SLFN11", "SLIRP", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCE1", "SMCHD1", "SMN1*", "SMPD4", "SMS", "SMYD3", "SMYD5", "SND1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SOAT1", "SOD2", "SON", "SORD", "SPCS2", "SPCS3", "SPEN", "SPOUT1", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SRCAP", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "STAMBP", "STAT1", "STAT3", "STAU1", "STK4", "STMN1", "STRBP", "STRN", "STT3A", "STT3B", "STUB1", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SULT2A1", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYNCRIP", "SYNE2", "TACO1", "TAF15", "TALDO1", "TAMM41", "TARDBP", "TARS", "TARS2", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TCEA1", "TCERG1", "TCF25", "TCP1", "TDP2", "TDRKH", "TECR", "TERF2IP", "TFAM", "TFRC", "THOC1", "THOC3", "THOP1", "THRAP3", "THUMPD3", "TIA1", "TIAL1", "TIMELESS", "TIMM13", "TIMM50", "TIMM8B", "TJP1", "TK1", "TKT", "TMCO1", "TMEM109", "TMOD3", "TMPPE", "TMTC3", "TOMM22", "TOMM34", "TOMM40", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOX4", "TP53", "TP53BP1", "TPI1", "TPM3", "TPM4", "TPP1", "TPP2", "TRA2A", "TRA2B", "TRAP1", "TRIM21", "TRIM25", "TRIM27", "TRIM28", "TRIP12", "TRMT10C", "TRMT11", "TRMT2A", "TROVE2", "TRUB1", "TSC2", "TSFM", "TSN", "TSNAX", "TSTA3", "TTK", "TTYH3", "TUFM", "TWF1", "TWF2", "TWNK", "TXNDC12", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3C", "UBE4A", "UBLCP1", "UBR4", "UBR5", "UBTF", "UCHL5", "UCK2", "UFL1", "UFSP2", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCRFS1", "UROD", "USP10", "USP11", "USP14", "USP19", "USP28", "USP33", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTRN", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VPS4A", "VRK1", "WARS", "WDHD1", "WDR1", "WDR18", "WDR43", "WDR5", "WRAP53", "WTAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPOT", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YKT6", "YME1L1", "YTHDC1", "YTHDC2", "ZADH2", "ZC3H14", "ZC3HAV1", "ZCCHC11", "ZCCHC3", "ZDHHC13", "ZFR", "ZMPSTE24", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF638", "ZNF687", "ZRANB2"], "leading_proteins": ["AARS2", "ABCC1", "AKT1", "AKT2", "ATG4B", "ATRX", "BAG4", "BAG6", "BCAT2", "BCS1L", "BIRC6", "BLMH", "BZW2", "CASP3", "CCDC47", "CDK13", "CDS2", "CEP55", "CHKA", "COASY", "CSTB", "CYP20A1", "DAXX", "DCD", "DENR", "DHX29", "DHX36", "DNAJA3", "DNAJB6", "DNAJC3", "DPM1", "EIF3A", "EIF3F", "EIF3M", "EIF4G1", "ERAL1", "ERAP1", "ERP44", "FKBP7", "FKBP9", "GADD45GIP1", "GNAI2", "GOT1", "GPT2", "H2AFY2", "HLTF", "HNRNPU", "HSPB1", "KIF2A", "KMT2A", "LCLAT1", "LIG1", "M6PR", "MAP2K2", "MAP3K7", "MARK2", "MCCC2", "MCTS1", "MCU", "MRPL12", "MRPL14", "MRPL17", "MRPL19", "MRPL28", "MRPL38", "MRPL40", "MRPL44", "MRPL50", "MRPL58", "MRPL9", "MRPS10", "MRPS17", "MRPS23", "MRPS27", "MRPS28", "MRPS35", "MRPS5", "MTIF2", "NAMPT", "NDUFAF7", "NDUFS3", "OGT", "OXSR1", "PARP2", "PCMT1", "PDXK", "PEBP1", "PGRMC2", "PIGK", "PIN4", "PKMYT1", "POLE", "PPIL1", "PRCP", "PRDX2", "PRDX3", "PRDX5", "PRDX6", "PSMB6", "PSMD10", "PSMD14", "PSME4", "PSMG1", "PSMG3", "PTCD3", "QKI", "RACGAP1", "RNF114", "RPL10A", "RPL12", "RPL13", "RPL22", "RPL23", "RPL23A", "RPL27", "RPL29", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL38", "RPL7", "RPL7A", "RPL9", "RPLP0", "RPLP2", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS18", "RPS19", "RPS2", "RPS3A", "RPS6", "RPS7", "RPS8", "RPS9", "RPSA", "SCARB1", "SERPINB6", "SMARCA1", "SPPL2A", "STK4", "STMN1", "STT3B", "TIMM13", "TOMM22", "TPP1", "TRMT11", "TTYH3", "UBA3", "UGGT1", "USP33", "XPOT", "YME1L1", "ZDHHC13", "ZMPSTE24"]} \ No newline at end of file diff --git a/protein_atlas_protein_class/advanced/idx2term.json b/protein_atlas_protein_class/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..d9d884224d4041b280400220e138a0d4558cc814 --- /dev/null +++ b/protein_atlas_protein_class/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Predicted membrane proteins", "1": "Transporters"} \ No newline at end of file diff --git a/protein_atlas_protein_class/advanced/plot_0.png b/protein_atlas_protein_class/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..7b800792fdad1fd28c5a3f82c915486e5e23dfaf --- /dev/null +++ b/protein_atlas_protein_class/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e8e3586f6464dcc6d7cc6a5dc42e63fa2b6e9d68799d4039d881e41ee6beadbd +size 221648 diff --git a/protein_atlas_protein_class/advanced/plot_1.png b/protein_atlas_protein_class/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..5b71a2414ca5aa08f23f52b77a6e94e680057ad2 --- /dev/null +++ b/protein_atlas_protein_class/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fc5b2fdfb15e1349108b65f0388808bdb60f166221ccca6bfdff05f5a640d4c1 +size 215992 diff --git a/protein_atlas_protein_class/basic/idx2term.json b/protein_atlas_protein_class/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..b5b22b39183c048160c0ec8ca725ed56d9cccd06 --- /dev/null +++ b/protein_atlas_protein_class/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Predicted membrane proteins", "1": "Transporters", "2": "RAS pathway related proteins", "3": "Ribosomal proteins", "4": "Transcription factors", "5": "FDA approved drug targets", "6": "Metabolic proteins"} \ No newline at end of file diff --git a/protein_atlas_protein_class/basic/plot_0.png b/protein_atlas_protein_class/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..53005fdc8f407251b690a45a62e49319747bf593 --- /dev/null +++ b/protein_atlas_protein_class/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:dd8674fd0212220f8352397b2d828f4286d7fa3a7e22034b57b1288cf419dd80 +size 142124 diff --git a/protein_atlas_protein_class/basic/plot_1.png b/protein_atlas_protein_class/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..dc96ca18819d39c1979e9cb49cf333e449b9767f --- /dev/null +++ b/protein_atlas_protein_class/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8fbb62586758954bfd7fa5c0e944bf32a7b3eb76d0a2d21446a7a9f811628049 +size 135135 diff --git a/protein_atlas_protein_class/basic/plot_2.png b/protein_atlas_protein_class/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..f4873a1d96b31acbba1d4fed1153694adbaf47a5 --- /dev/null +++ b/protein_atlas_protein_class/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:11a8efe50e94f8f0ac6e16f3715f1f12a99851ef5dbf8af68eca34c7698c113e +size 137782 diff --git a/protein_atlas_protein_class/basic/plot_3.png b/protein_atlas_protein_class/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..6dde0cc827d5b189defc765d1d60e3aa699f9531 --- /dev/null +++ b/protein_atlas_protein_class/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:417ae51dbdbee79ae2ebceaf7b9d3bfb336786c8648d0b4056c4957d7001da2f +size 144138 diff --git a/protein_atlas_protein_class/basic/plot_4.png b/protein_atlas_protein_class/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..03f17e19881dcada821eeb9a0c4a50963b538220 --- /dev/null +++ b/protein_atlas_protein_class/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:83d5c8513c6ca7393d19b2eca97ba4f33559f32027504cd736573424ed0f8608 +size 141490 diff --git a/protein_atlas_protein_class/basic/plot_5.png b/protein_atlas_protein_class/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..db7442bbbeb32edce6e4628282d64fdc3c700005 --- /dev/null +++ b/protein_atlas_protein_class/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3d281eb76416689436d0e2d5a7a434bf48079240b3b815e1f262129aaedb90b2 +size 148721 diff --git a/protein_atlas_protein_class/basic/plot_6.png b/protein_atlas_protein_class/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..5d09ca9d7e034cecd2acede4312773365d0f3163 --- /dev/null +++ b/protein_atlas_protein_class/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:00dc2367850f29b9d2b7ad7cb4d1d35fb9579f31890ba6aaa94d1f2d41ef4077 +size 136379 diff --git a/protein_atlas_protein_class/consensus.joblib b/protein_atlas_protein_class/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..d2a364daf6607f0b492169ace1596540e80e7b0e --- /dev/null +++ b/protein_atlas_protein_class/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bbda981b21b8c89c3f615802a8c0855a04e3ef0f0dd1d75e87694f753f9dd271 +size 77450 diff --git a/protein_atlas_protein_class/df_merge.tsv b/protein_atlas_protein_class/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c47f0dfb3840f95252417518ccdd5a4a2c0b7ad2 --- /dev/null +++ b/protein_atlas_protein_class/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Predicted membrane proteins 94 465 3.1396601670647906 0.0016914392327822 204.61650485436897 563.8058252427185 3.080866334016093 0.3028099075873978 81.17076282318972 73.52280648113661 4.068861305085399 0.4187410497068249 0.2026284817520567 0.0104529798673135 0.0025262216152607 0.0003273993174906 0.0200576132491455 +Transporters 66 327 2.5008094056104437 0.0123909843343843 108.9004854368932 367.3009708737864 1.469396346451591 0.4764419032567517 40.40141182476491 35.10022679965902 2.352674986871393 0.4490473364946538 1.0 0.0282273542102413 9.22918931506897e-05 6.350491480213074e-05 7.778371863604057e-05 diff --git a/protein_atlas_protein_class/metrics.json b/protein_atlas_protein_class/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..e658324d1118562e73a746123d1358ee0d13177c --- /dev/null +++ b/protein_atlas_protein_class/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2772, + "annotations_size": 20, + "title": "Average number of proteins per term", + "value": 450.5 +} \ No newline at end of file diff --git a/protein_atlas_protein_class/paths.json b/protein_atlas_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..508a126e6c55a6a1430dfcfaa7c2c0d4fe914392 --- /dev/null +++ b/protein_atlas_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_protein_class/fragment/C321/C321_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_protein_class/result.tsv b/protein_atlas_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..eb292d91a8230b5d1b5e340eb4cc913433652844 --- /dev/null +++ b/protein_atlas_protein_class/result.tsv @@ -0,0 +1,9 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Predicted membrane proteins 0.3659767432631097 3.1396601670647906 0.0016914392327822 0.0332906781760372 0.0112762615518817 465 Q13505,O60830,Q99595,Q8IUH4,Q6UW02,P33527,Q8WTV0,P00846,Q16850,Q14728,Q8NCC3,Q9NS69,O75844,O75027,Q8N4V1,Q9Y639,Q8TCT8,Q8NE86,O60637,Q6ZT21,P20645,P22061,Q8N2K0,Q9UDW1,Q06136,Q70HW3,Q9Y2W6,Q15070,Q9BUN8,Q9H1E5,O15439,O43169,Q9C0H2,O15173,Q9Y282,Q14789,P30519,O43676,P09601,Q9NX00,Q9BVC6,Q8IXU6,O95470,Q8NE01,O95674,Q8NBN3,P78310,O43760,Q9H4I3,Q6P4A7,O00461,Q5JTV8,Q15392,Q8TAD4,O75915,O75448,Q86Y39,Q15800,Q96TA2,Q52LJ0,Q9NX14,Q9Y584,O14925,Q3B7T1,Q96KA5,Q96A33,Q5SWX8,Q9Y3P9,Q8TB61,P51648,O94901,Q9Y3E5,O95202,Q6PI78,Q9Y276,Q9H2U1,O95197,Q9NX62,Q9NPR9,Q92643,P04844,Q5JRA6,Q9UBX3,Q8NC44,Q96G23,P62244,Q8TCJ2,Q99640,Q99986,Q9NPA0,Q9UDX5,O00767,O95140,P09669 94 +Transporters 0.3381871861028777 2.5008094056104433 0.0123909843343843 0.2207067453208162 0.0495639373375373 327 O95202,Q9Y276,Q9C0E2,Q8IUH4,P78310,O76024,P33527,Q6P4A7,Q8WTV0,P35609,Q9NRK6,P14635,P52294,P57105,O75844,Q8TAD4,O75915,P54105,O75027,Q8N4V1,Q9Y639,Q8TCT8,Q9H2D1,O60637,Q99808,P20645,P04844,Q9BQT8,Q5JRA6,Q96A65,Q5SRE5,Q9UBX3,Q16799,Q96KP1,P21281,O15397,P04843,P31749,Q10567,Q70HW3,Q8TCJ2,Q01469,Q15070,Q9BUN8,Q96A33,Q9NPA0,Q8NE71,O15439,O94973,Q9Y4P1,O95140,O75436,Q8TB61,O00161,Q9C0H2,Q9UI26,Q96RL7,Q9BVC6,Q8TAG9,Q8IXU6,P80723,P81605,O14745,O94901,O43592,Q8NE01 66 +RNA polymerase related proteins 0.6415186442893421 1.4860922301640216 0.1372547271898629 0.9478022518865926 0.3100482036584356 10 P19388 1 +RAS pathway related proteins 0.4911970727329465 1.477574545718101 0.139521691646296 0.9504779590471908 0.3100482036584356 26 Q96KP1,P20936,P31749,P31751,Q13043,P36507,P20339 7 +Ribosomal proteins 0.3368058928112378 1.1597305162863978 0.2461585415995835 0.9964876291340428 0.4102642359993058 119 P62906,Q96DV4,Q9Y3D9,P18077,Q6P1L8,O95478,P52815,P62249,P62910,Q9Y3U8,P62899,Q9Y2R5,P62753,P62424,P82664,P62841,Q9NRX2,P32969,P62263,P62081,P15880,P30050,Q96EY7,P82673,P62241,Q13084,Q8N5N7,P35268,P82675,P62244,P62269,Q9BYD2,P39019,Q14197,P62750,P61247,Q8TAE8,P08865,Q9NQ50,P05388,P61353,P42766,P18124,Q9Y2Q9,P05387 45 +Transcription factors 0.3677195345381341 0.9474593843695848 0.3434047431875759 0.999778203431885 0.5097668380732111 42 Q03164,Q96KM6,Q86YP4,P46100,P28370,O94842,P17096 7 +FDA approved drug targets 0.3181895616422348 0.8736201876554475 0.3823251285549083 0.999934657060102 0.5097668380732111 109 P68371,P21281,O00764,P49356,P54619,P49721,P00374,P22033,P23786,P33527,Q9UGN5,P20645,Q16850,P36507,P42574,Q07864 16 +Metabolic proteins 0.245103598853235 0.6134143924959592 0.5396023718910627 0.9999998169112958 0.5995581909900697 797 O95747,Q03164,P19388,Q7KZI7,Q8IUH4,Q16822,Q9Y237,Q15165,P09455,Q9Y5P4,Q9HC38,Q9HCC0,P33527,Q8WTV0,P00846,Q16850,Q8NCC3,O14773,O75844,P22570,P49356,Q8N4Q0,Q6ZT21,O60502,P22061,Q9BQT8,Q8N2K0,O00764,Q9UDW1,P31749,Q06136,O75489,Q70HW3,Q01469,O15439,P49593,Q07864,Q96P11,P30519,O43676,P09601,P35790,O95470,Q9UHG3,Q9UNE7,O95674,Q13057,Q8TEY7,Q15102,P14927,Q9NZD2,O95302,Q15392,Q9Y3C6,Q96ST3,Q8TBC4,Q86Y39,Q15800,Q9UGN5,Q9NX14,P21281,O43318,Q01968,Q16763,P31751,P56385,P43490,Q13043,Q9NYU2,Q8TB61,Q14195,Q04760,P51648,P00374,P61457,Q96SZ5,Q7Z4G4,Q9Y3E5,O75223,Q9H9Y6,Q14527,Q08209,P36507,Q9NX62,Q92643,Q14004,O15254,Q9H2D1,Q9BQG2,O60762,Q7L2J0,P04844,Q5JRA6,Q5SRE5,Q9UBX3,Q96G23,Q15067,P49589,Q8TD30,Q8TCJ2,Q99640,Q99986,P61088,P23786,O00767,P07954 106 diff --git a/protein_atlas_protein_class/selections.json b/protein_atlas_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..dbbca0565e2f376cdad6ac75dcf3f37dce84819d --- /dev/null +++ b/protein_atlas_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Blood group antigen proteins", "CD markers", "Cancer-related genes", "Candidate cardiovascular disease genes", "Citric acid cycle related proteins", "Disease related genes", "Enzymes", "FDA approved drug targets", "Human disease related genes", "Metabolic proteins", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Predicted secreted proteins", "RAS pathway related proteins", "RNA polymerase related proteins", "Ribosomal proteins", "Transcription factors", "Transporters"], "available_proteins": ["AAAS", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAP2", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADH5", "ADI1", "ADK", "ADNP", "ADO", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP17A", "AKAP8", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT1S1", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALKBH5", "AMOT", "ANAPC16", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANKRD28", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP3B1", "AP3D1", "AP3M1", "APEH", "APEX1", "API5", "APMAP", "APOL2", "APOOL", "APRT", "AQR", "ARCN1", "ARF4", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL6IP4", "ARL6IP5", "ARL8B", "ARMC1", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "AS3MT", "ASAH1", "ASCC2", "ASCC3", "ASNA1", "ASNS", "ASPH", "ASPM", "ASRGL1", "ATAD1", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATG4B", "ATIC", "ATL2", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7B", "ATPAF1", "ATPIF1", "ATRX", "ATXN10", "ATXN2L", "AUP1", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAK1", "BANF1", "BAP18", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BCAP31", "BCAS2", "BCAT2", "BCCIP", "BCL10", "BCL2L12", "BCL2L13", "BCLAF1", "BCS1L", "BET1", "BIRC6", "BLMH", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOP1", "BPNT1", "BRD2", "BRI3BP", "BRIX1", "BSG", "BTF3", "BUB3", "BUD31", "BYSL", "BZW1", "BZW2", "C11orf58", "C12orf43", "C12orf73", "C15orf39", "C19orf25", "C19orf70", "C1QBP", "C1orf123", "C1orf35", "C20orf27", "C21orf59", "C2CD2", "C2CD5", "C2orf49", "C5orf15", "CAB39", "CACUL1", "CACYBP", "CAD", "CALD1", "CALR", "CALU", "CAND1", "CANX", "CAP1", "CAPN1", "CAPRIN1", "CAPZA1", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP2", "CASP3", "CASP6", "CAST", "CBFB", "CBR1", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC124", "CCDC47", "CCDC6", "CCDC86", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD276", "CD2AP", "CD2BP2", "CD47", "CD81", "CDC123", "CDC23", "CDC27", "CDC37", "CDC42", "CDC45", "CDC5L", "CDC73", "CDCA8", "CDK1", "CDK13", "CDK2", "CDK4", "CDK5RAP3", "CDK6", "CDKAL1", "CDKN2AIP", "CDS2", "CDV3", "CEBPZ", "CELF1", "CELF2", "CENPV", "CEP170", "CEP44", "CEP55", "CERS2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP2A", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP2", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLP1", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTA", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNOT1", "CNOT11", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG7", "COIL", "COL4A3BP", "COLGALT1", "COMMD10", "COMMD2", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "CORO1C", "COTL1", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZL1", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWC22", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DCAF13", "DCAF7", "DCAKD", "DCD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHFR", "DHPS", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX40", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIP2B", "DIS3", "DIS3L2", "DKC1", "DLAT", "DLD", "DLST", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOHH", "DPF2", "DPH2", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DRG1", "DRG2", "DSG2", "DSP", "DST", "DSTN", "DTL", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFL1", "EFTUD2", "EHD1", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENDOD1", "ENO1", "ENOPH1", "ENSA", "ENY2", "EPB41", "EPB41L2", "EPB41L3", "EPHX1", "EPHX2", "EPPK1", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERC1", "ERCC2", "ERCC6L", "ERGIC3", "ERH", "ERI1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EYA3", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAHD2A", "FAM114A2", "FAM120A", "FAM120B", "FAM136A", "FAM162A", "FAM177A1", "FAM208A", "FAM3C", "FAM49B", "FAM8A1", "FAM91A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FBL", "FBXO22", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FLCN", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNBP4", "FNDC3A", "FNTA", "FNTB", "FOXC1", "FOXRED1", "FRG1", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLM", "GCN1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GHITM", "GIGYF2", "GINS1", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLTP", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GNS", "GOLGA3", "GOLGB1", "GOLIM4", "GOPC", "GOT1", "GOT2", "GPAA1", "GPD2", "GPI", "GPKOW", "GPR107", "GPR108", "GPS1", "GPT2", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2E1", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP4", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS4", "HAUS5", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDGFL2", "HDHD2", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEBP1", "HECTD1", "HELLS", "HELZ", "HERC2", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HP1BP3", "HPRT1", "HPS6", "HS1BP3", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "ILF2", "ILF3", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPAD1", "IMPDH2", "INA", "INCENP", "INF2", "INTS3", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IRF2BPL", "IRS4", "ISCU", "ISOC1", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPK1", "IVD", "JPT2", "JUP", "KARS", "KAT7", "KCTD12", "KCTD5", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM3B", "KDSR", "KHDRBS1", "KHSRP", "KIAA0368", "KIF11", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KLC1", "KLC2", "KLC4", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LAMP1", "LAMTOR1", "LAMTOR2", "LANCL1", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDAH", "LDHA", "LDHB", "LEMD3", "LENG8", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRCH2", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC59", "LRWD1", "LSG1", "LSM12", "LSM14A", "LSM14B", "LSM2", "LSM6", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LZTFL1", "LZTS2", "M6PR", "MACF1", "MAGED2", "MAK16", "MANF", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MCAT", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED17", "MED24", "MED25", "MEPCE", "MESD", "METTL1", "METTL13", "MFF", "MFN2", "MFSD10", "MFSD5", "MGEA5", "MGST2", "MGST3", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MIPEP", "MKI67", "MLEC", "MMAB", "MMGT1", "MMS19", "MOGS", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP2", "MPP6", "MPRIP", "MPST", "MPV17L2", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL44", "MRPL46", "MRPL50", "MRPL58", "MRPL9", "MRPS10", "MRPS15", "MRPS17", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTX1", "MTX2", "MTX3", "MUT", "MVD", "MVK", "MXRA7", "MYBBP1A", "MYDGF", "MYG1", "MYH10", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA25", "NAA35", "NAA40", "NAA50", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCAPH2", "NCBP1", "NCDN", "NCK1", "NCKAP1", "NCL", "NCLN", "NCOA5", "NCSTN", "NDC1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4", "NEFL", "NEFM", "NEK9", "NELFA", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NFS1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPA2", "NIPSNAP2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NME1", "NME2", "NMT1", "NNT", "NOC2L", "NOC3L", "NOC4L", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOSIP", "NOVA2", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NSA2", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSMCE2", "NSUN2", "NSUN5", "NSUN6", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDT1", "NUDT12", "NUDT16L1", "NUDT21", "NUDT5", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCRL", "ODR4", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC3", "OSBP", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OTULIN", "OXA1L", "OXSR1", "P3H1", "P4HA1", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAK1IP1", "PAK2", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PASK", "PATL1", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDS5A", "PDS5B", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF2", "PHF3", "PHF5A", "PHF6", "PHGDH", "PHIP", "PI4K2A", "PICALM", "PIGK", "PIGS", "PIGU", "PIH1D1", "PIK3C2A", "PIN1", "PIN4", "PINX1", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN2", "PLA2G15", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PMVK", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPO", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPHLN1", "PPIB", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R1", "PPP5C", "PPT1", "PPT2", "PQBP1", "PRAF2", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF39", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTRH2", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXN", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB21", "RAB24", "RAB35", "RAB39A", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB8B", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD51AP1", "RAE1", "RAI14", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP1GDS1", "RAPGEF2", "RARS", "RASA1", "RAVER1", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM8A", "RBMX", "RBMXL1", "RBP1", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "REEP5", "RER1", "RETREG2", "RETREG3", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFLNB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RINT1", "RMDN1", "RMDN3", "RNASEH2A", "RNASEH2B", "RNASET2", "RNF114", "RNF14", "RNF40", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP3", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSBN1", "RSF1", "RSL1D1", "RSU1", "RTCB", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMHD1", "SAMM50", "SAP18", "SAP30BP", "SAR1A", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDCBP", "SDE2", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC63", "SEH1L", "SEL1L", "SENP3", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD7", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN4", "SGPL1", "SGTA", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIN3A", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC30A5", "SLC35B2", "SLC35F2", "SLC3A2", "SLC4A1AP", "SLC9A3R1", "SLFN11", "SLIRP", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SMYD3", "SMYD5", "SNAP23", "SNAP29", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SOAT1", "SOD2", "SON", "SORD", "SPAG9", "SPART", "SPATA5L1", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPECC1L", "SPEN", "SPOUT1", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STIM2", "STIP1", "STK4", "STMN1", "STOML2", "STRAP", "STRBP", "STRN", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX17", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SULT2A1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACC3", "TACO1", "TAF15", "TAGLN2", "TALDO1", "TAMM41", "TARDBP", "TARS", "TARS2", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF25", "TCOF1", "TCP1", "TDP2", "TDRKH", "TECR", "TELO2", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFG", "TFIP11", "TFRC", "TGOLN2", "THOC1", "THOC3", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "TIA1", "TIAL1", "TIMELESS", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TK1", "TKT", "TLN1", "TM9SF2", "TM9SF3", "TMA16", "TMCO1", "TMED10", "TMED2", "TMED7", "TMEM109", "TMEM11", "TMEM126A", "TMEM14C", "TMEM160", "TMEM192", "TMEM199", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM33", "TMEM43", "TMEM65", "TMEM87A", "TMEM97", "TMOD3", "TMPPE", "TMTC3", "TMX1", "TMX2", "TMX4", "TNPO1", "TNPO2", "TOE1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOX4", "TP53", "TP53BP1", "TPD52", "TPD52L2", "TPI1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRIM21", "TRIM25", "TRIM27", "TRIM28", "TRIP12", "TRIP13", "TRMT10C", "TRMT11", "TRMT112", "TRMT2A", "TRMT6", "TROVE2", "TRUB1", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPYL1", "TSR1", "TSTA3", "TTC1", "TTC19", "TTC26", "TTC37", "TTC38", "TTC4", "TTI1", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE2V1", "UBE3C", "UBE4A", "UBLCP1", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UFSP2", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "UROD", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP19", "USP28", "USP33", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VPS13A", "VPS18", "VPS26A", "VPS29", "VPS33A", "VPS35", "VPS4A", "VPS51", "VPS53", "VRK1", "VRK3", "WAPL", "WARS", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR18", "WDR3", "WDR33", "WDR36", "WDR41", "WDR43", "WDR46", "WDR5", "WDR6", "WDR61", "WDR70", "WDR73", "WDR75", "WDR77", "WDR82", "WFS1", "WIPI2", "WIZ", "WRAP53", "WTAP", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YKT6", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZDHHC13", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM4", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF622", "ZNF638", "ZNF687", "ZPR1", "ZRANB2", "ZW10", "ZYX"], "leading_proteins": ["ABCB10", "ABCB7", "ABCC1", "ABCC4", "ABCF1", "ABHD12", "ACOX1", "ACOX3", "ACTN2", "ADO", "AKT1", "AKT2", "ALDH3A2", "AP1B1", "AP2A2", "ARL6IP5", "ATG4B", "ATP5I", "ATP6", "ATP6V1B2", "ATRX", "BASP1", "BCS1L", "CARS", "CASP3", "CCDC47", "CCNB1", "CDK13", "CDS2", "CERS2", "CHKA", "CLNS1A", "CLPTM1L", "CNNM3", "COASY", "COL4A3BP", "COX6C", "CPT2", "CXADR", "CYB5B", "CYP20A1", "CYP51A1", "DCD", "DERL1", "DHCR24", "DHFR", "DHX36", "DPM1", "DPYSL3", "EDRF1", "EMC7", "ERGIC3", "EXOC2", "EXOC4", "EXOC6", "FABP5", "FAM98B", "FDXR", "FH", "FKBP9", "FNTB", "GADD45GIP1", "GATAD2A", "GGCT", "GLO1", "GLOD4", "GLTP", "GOLGB1", "GOLIM4", "GPR108", "GPT2", "HLTF", "HMGA1", "HMOX1", "HMOX2", "IMPAD1", "IPO11", "IPO8", "KDSR", "KMT2A", "KPNA1", "LETM1", "M6PR", "MAP2K2", "MAP3K7", "MARK2", "MCCC2", "MCU", "MED24", "MEPCE", "MFN2", "MFSD10", "MGEA5", "MIA3", "MMGT1", "MRPL12", "MRPL14", "MRPL17", "MRPL28", "MRPL38", "MRPL40", "MRPL50", "MRPL58", "MRPL9", "MRPS10", "MRPS17", "MRPS23", "MRPS28", "MRPS35", "MRPS5", "MSMO1", "MTFP1", "MTX1", "MUT", "NAMPT", "NDUFA11", "NDUFB11", "NDUFB3", "NDUFS3", "NPTN", "NSA2", "NSUN5", "NUDT12", "NUP188", "OCRL", "ODR4", "OXA1L", "OXSR1", "PAFAH1B3", "PARP2", "PCBD1", "PCK2", "PCMT1", "PCYOX1", "PDXK", "PGRMC2", "PIGK", "PIN4", "PKMYT1", "PLA2G15", "POLE", "POLR1B", "POLR2E", "PON2", "PPIL1", "PPM1F", "PPP3CA", "PRKAG1", "PSMB2", "PTCD3", "PTRH2", "RAB5A", "RABGAP1", "RASA1", "RBP1", "RETREG2", "RPL10A", "RPL12", "RPL22", "RPL23A", "RPL27", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL7", "RPL7A", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS18", "RPS19", "RPS2", "RPS3A", "RPS6", "RPS7", "RPS8", "RPSA", "RTN1", "RTN3", "SCARB1", "SCD", "SFXN4", "SGPL1", "SIN3A", "SLC25A10", "SLC25A21", "SLC25A26", "SLC25A32", "SLC29A1", "SLC30A5", "SLC35B2", "SLC35F2", "SLC9A3R1", "SMARCA1", "SNAP23", "SPPL2A", "STK4", "STT3B", "STUB1", "SUN1", "SYNGR2", "SYNJ2BP", "TDRKH", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TMEM109", "TMEM160", "TMEM65", "TMEM87A", "TMPPE", "TMX4", "TOMM22", "TOR1AIP1", "TOX4", "TPP1", "TRABD", "TRMT11", "TSPAN3", "TTYH3", "TUBB4B", "UBA3", "UBE2N", "UBE2S", "UGGT1", "UQCR10", "UQCRB", "USP33", "VPS13A", "VPS26A", "VRK1", "WFS1", "XPO4", "XPOT", "YME1L1", "ZADH2", "ZDHHC13", "ZMPSTE24", "ZNF512B"]} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/advanced/idx2term.json b/protein_atlas_subcellular_location_all/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..5e886d2af5bf757e821a3be931005c58463adc14 --- /dev/null +++ b/protein_atlas_subcellular_location_all/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondria"} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/advanced/plot_0.png b/protein_atlas_subcellular_location_all/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..1589196b73fac13a53beced71115eb9e1bd62a99 --- /dev/null +++ b/protein_atlas_subcellular_location_all/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0e836646a72b8bbe72f881b626aa5aff1462494802a17581469f181c4cbc523a +size 214896 diff --git a/protein_atlas_subcellular_location_all/basic/idx2term.json b/protein_atlas_subcellular_location_all/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..50d52b4eddb0ca87a6e57a1bf93f2177b332b3f3 --- /dev/null +++ b/protein_atlas_subcellular_location_all/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondria", "1": "Cell Junctions", "2": "Golgi apparatus", "3": "Microtubules", "4": "Midbody", "5": "Plasma membrane", "6": "Centrosome", "7": "Endoplasmic reticulum", "8": "Cytokinetic bridge", "9": "Mitotic spindle"} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/basic/plot_0.png b/protein_atlas_subcellular_location_all/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..b6b07a2e58e4c583ce56a572dd0bc83db3d070d6 --- /dev/null +++ b/protein_atlas_subcellular_location_all/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0a9817a82307e056b7285d089f82bf575cb33f8a0e7f7502e5c346a75e9b70a3 +size 133301 diff --git a/protein_atlas_subcellular_location_all/basic/plot_1.png b/protein_atlas_subcellular_location_all/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..6c472135d24ab7d95d2076ee5ee612e2a7cb6cef --- /dev/null +++ b/protein_atlas_subcellular_location_all/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:394860f4d8c7eaf866c5c457b0ce91a7a7a6fbd411d5820ffaeb6ef2e418e935 +size 135129 diff --git a/protein_atlas_subcellular_location_all/basic/plot_2.png b/protein_atlas_subcellular_location_all/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..ca810bbb5a9b2bf7abdc26e4d70b77439c911fdb --- /dev/null +++ b/protein_atlas_subcellular_location_all/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ce1c2acffe49d253d4d708aec2bdb957ddf39d0382f4c1d6c15a16de5c6078ae +size 139212 diff --git a/protein_atlas_subcellular_location_all/basic/plot_3.png b/protein_atlas_subcellular_location_all/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..f107af0300694149e4ea6f381fe5e36ba1dadfa4 --- /dev/null +++ b/protein_atlas_subcellular_location_all/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:aae3336e0ff14b4cc7a14b556f69e564a155c58768506e4bcc25d3e4c9799ae4 +size 120874 diff --git a/protein_atlas_subcellular_location_all/basic/plot_4.png b/protein_atlas_subcellular_location_all/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..469da67d7e694c5768f3ec7f94edeacf3ef3baa5 --- /dev/null +++ b/protein_atlas_subcellular_location_all/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:394373ec727d4bf3ca8a874998a1c0c11a147b6909c8b99b46ce013c1f041bed +size 130307 diff --git a/protein_atlas_subcellular_location_all/basic/plot_5.png b/protein_atlas_subcellular_location_all/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..a88d4ec8fc6969c10d76356b71b42675e2b0e28e --- /dev/null +++ b/protein_atlas_subcellular_location_all/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:58fe31b8c0410db46357a3c3715f9d411ee49f603ac5bcb16901981ed50c5da6 +size 142690 diff --git a/protein_atlas_subcellular_location_all/basic/plot_6.png b/protein_atlas_subcellular_location_all/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..1ec6bbf03cae066abcd721971d75c6719f20277a --- /dev/null +++ b/protein_atlas_subcellular_location_all/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f38d0eb9da7aa07fc9635b30b69b63f65a38b4efdf7672aa28b5bcb4e6bf5830 +size 144590 diff --git a/protein_atlas_subcellular_location_all/basic/plot_7.png b/protein_atlas_subcellular_location_all/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..fe7878741df0d34dbcb200ce1035bd08f4286a37 --- /dev/null +++ b/protein_atlas_subcellular_location_all/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3e7bebe32c7f930b0727c2914b6a2260948561e9e050eef21938432c195c4f4e +size 142192 diff --git a/protein_atlas_subcellular_location_all/basic/plot_8.png b/protein_atlas_subcellular_location_all/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..38f5c9b8a199dbcda2ead9bee565182a0ceb76fa --- /dev/null +++ b/protein_atlas_subcellular_location_all/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:45095646c3a029e9e2199f3f9f3eb8e1919b474244a0bd6cffafdb95a5b2058e +size 147779 diff --git a/protein_atlas_subcellular_location_all/basic/plot_9.png b/protein_atlas_subcellular_location_all/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..8cb22962ee34b6bfe19a0e9e84c2f6c56da9e648 --- /dev/null +++ b/protein_atlas_subcellular_location_all/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:865dc29f32fef5cb316206d1c9860b8db4b4dca6d552a1b6bd1b34c12dc9e7da +size 146075 diff --git a/protein_atlas_subcellular_location_all/consensus.joblib b/protein_atlas_subcellular_location_all/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..273d5c418c5e667ddf129488063ec157f7f52c47 --- /dev/null +++ b/protein_atlas_subcellular_location_all/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6794273b6cd27e683c7481f0a3cfff0a4d72b09cb35942e8a40d7d4f946df17c +size 63096 diff --git a/protein_atlas_subcellular_location_all/df_merge.tsv b/protein_atlas_subcellular_location_all/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..5158a5b94f990dd418660496eefeeeb4262a6687 --- /dev/null +++ b/protein_atlas_subcellular_location_all/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Mitochondria 74 350 2.3429564258251374 0.0191316173332238 110.1747572815534 400.5485436893204 0.4320244196044261 0.5794127039570083 42.49664228528663 36.15232166758906 2.0400795827803786 0.4211568684384254 0.0850333464085965 0.0062466307877426 0.002202367883971 5.80939572325806e-05 9.662402462227793e-08 diff --git a/protein_atlas_subcellular_location_all/metrics.json b/protein_atlas_subcellular_location_all/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..f20c31280218704586d6bb44e5dfacc2754de82b --- /dev/null +++ b/protein_atlas_subcellular_location_all/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2772, + "annotations_size": 33, + "title": "Average number of proteins per term", + "value": 131.42424242424244 +} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/paths.json b/protein_atlas_subcellular_location_all/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..f6bae50863d185fe2e7bb621110512608678807b --- /dev/null +++ b/protein_atlas_subcellular_location_all/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_subcellular_location_all/fragment/C321/C321_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/result.tsv b/protein_atlas_subcellular_location_all/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c51862b1b26b15b2aa3ba0331887e6f33a7abffa --- /dev/null +++ b/protein_atlas_subcellular_location_all/result.tsv @@ -0,0 +1,17 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mitochondria 0.3217191804507597 2.3429564258251374 0.0191316173332238 0.4713669907372594 0.315671685998194 350 Q13505,O95202,O60830,Q8NBU5,Q99595,Q9H2U1,Q9NUJ1,Q96DV4,Q5ST30,Q16822,Q9NVI7,Q9Y5L4,Q9Y3D9,P22033,Q9H4I3,Q9HCC0,Q6P1L8,Q8N5C6,Q6P4A7,O95302,P82664,Q9NS69,Q5VT66,P57105,P36551,P22570,P51970,O75027,Q86Y39,Q9H2D1,Q8NE86,Q69YU5,Q6ZT21,Q9Y2R0,Q96TA2,Q5TC12,Q5XKP0,Q16851,Q9NX14,Q5JPH6,Q9UBX3,Q96EY1,Q13084,O14949,O15498,O14925,P13073,P82675,O75489,Q9BYD2,Q86U90,Q70HW3,Q8TD30,Q8TAE8,Q04837,Q9NQ50,Q15070,Q9BX68,Q9UDX5,P56385,Q9UII2,P23786,O95140,P07954,P09669,Q8TB37,Q99797,P00374,Q9Y3E5,Q9Y2Q9,P42574,P04179,Q9Y3B8,Q5HYI7 74 +Cell Junctions 0.4425552967199552 1.6037139145685246 0.1087771273538202 0.9776360410114856 0.8242407471002227 39 Q9UPN3,O15126,P20337,P14923,P78310,Q9UJA5,Q6UW02,Q15369,P33527,Q7L2J0,Q9Y624,P43490,Q9NPJ3,P15924 14 +Golgi apparatus 0.3305032229547905 1.5075424797487662 0.1316716638479547 0.990525176506961 0.8242407471002227 152 Q8TEY7,Q8NBN3,Q8IUH4,P80303,Q969S3,Q9Y5P4,O43760,P07305,O00461,O95302,Q8IWJ2,Q9NX62,Q9NPR9,P18858,Q8TAD4,Q8N4Q0,O60637,O95456,Q10567,P53365,O15439,Q14789,P09601,Q8IXU6 24 +Microtubules 0.3956909828877482 1.2072385520960636 0.2273402874431707 0.9997988070076854 0.8242407471002227 45 P68371,O60830,P54105,Q01968,P31749,P41223,Q8WWK9,O43768,Q9NSV4,Q96E11,Q9Y624,O43663 12 +Lysosomes 0.5216625375670922 1.1902136889197503 0.2339624142184408 0.9998485558145698 0.8242407471002227 13 Q13596,Q8WTV0 2 +Midbody 0.4972219566504625 1.1872361220063152 0.2351344964410855 0.9998560182507114 0.8242407471002227 15 P28838,Q53EZ4,Q7Z7K6,Q99661,P07196,Q9NQW6,O43663 7 +Mitotic chromosome 0.3655178101618514 0.8412364580149608 0.4002154798910569 0.9999999528107208 1.0 36 Q76FK4,Q9Y237 2 +Plasma membrane 0.2795265669099008 0.5328105942053257 0.5941646994493659 0.999999999999881 1.0 250 Q9UQB8,Q7KZI7,P78310,Q6UW02,P33527,P04899,Q8N5W9,Q8TBC4,Q9Y639,Q69YU5,P04792,P26038,O43318,Q8IZT6,Q16763,Q9NZ08,Q9H074,Q01469,Q5SWX8,O15439,P49593,Q07864,Q04760,O15173,P14923,P09601,P80723 27 +Centriolar satellite 0.3447621269031036 0.4653332764208469 0.6416928083034725 0.999999999999998 1.0 21 O43169,O14745,Q01968,Q12756 4 +Centrosome 0.2998589068801836 0.4279908023373273 0.668657816774864 1.0 1.0 59 O75934,Q3B7T1,P49356,P41223,Q8WWK9,Q99661,Q8TBC4,Q9H0R6,Q9Y2W6,O43237,Q69YU5,Q2NKX8,Q9BRR6,O00139,P40222,Q16851 16 +Endoplasmic reticulum 0.2567156233840709 0.2654116746598172 0.7906923434961508 1.0 1.0 185 P55145,O95674,Q9Y680,Q8TED0,P62906,P62820,Q14318,Q86UE4,P30533,Q96A57,O95197,Q16850,P62249,Q9P265,P62910,Q9Y3U8,P62753,P62841,O75915,P32969,P62263,P62081,P15880,P43307,P84157,Q8NHP6,Q13217,Q86UP2,Q15800,Q96CN7,P04844,Q9H0P0,Q96HY6,P62241,Q16799,P04843,Q96G23,O14967,P62750,Q6UWP7,Q8TCJ2,Q9BUN8,Q96KA5,Q96A33,Q15631,O00767,O15260,O43169,Q9GZP9,P42766,O96005,P51648,P35790,Q9NVZ3,O95470,O60831,Q86XL3,P35610 58 +Cytokinetic bridge 0.2831125207233977 0.16857764575701 0.8661288649894283 1.0 1.0 24 P68371,P04350,Q53HL2,Q96QE3,Q96E11,Q13885,O43663 7 +Midbody ring 0.3622338960445456 0.1454935677302459 0.8843211939225002 1.0 1.0 5 Q02241 1 +Mitotic spindle 0.2745889343122901 0.1262877035633912 0.8995041894633584 1.0 1.0 19 P68371,P04350,Q02241,Q8WWK9,P05387 5 +Actin filaments 0.2519359236574839 0.0857972532478449 0.9316275900194018 1.0 1.0 46 P35609,Q8N5W9,P07305,Q6UW02 4 +Intermediate filaments 0.2339502340597291 0.0123424166065638 0.9901524263693552 1.0 1.0 29 O75832,Q15102,P58107,P07196 4 diff --git a/protein_atlas_subcellular_location_all/selections.json b/protein_atlas_subcellular_location_all/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..964f27416f96770acc7d579a15cf71fe3b2c51cb --- /dev/null +++ b/protein_atlas_subcellular_location_all/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin filaments", "Cell Junctions", "Centriolar satellite", "Centrosome", "Cytokinetic bridge", "Cytoplasmic bodies", "Cytosol", "Endoplasmic reticulum", "Endosomes", "Focal adhesion sites", "Golgi apparatus", "Intermediate filaments", "Kinetochore", "Lipid droplets", "Lysosomes", "Microtubule ends", "Microtubules", "Midbody", "Midbody ring", "Mitochondria", "Mitotic chromosome", "Mitotic spindle", "Nuclear bodies", "Nuclear membrane", "Nuclear speckles", "Nucleoli", "Nucleoli fibrillar center", "Nucleoli rim", "Nucleoplasm", "Peroxisomes", "Plasma membrane", "Rods & Rings", "Vesicles"], "available_proteins": ["AAAS", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASS", "AATF", "ABCB1", "ABCB7", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD14B", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAP2", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ADA", "ADAR", "ADD1", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP17A", "AKAP8", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT1S1", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALKBH5", "AMOT", "ANAPC16", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP3B1", "AP3D1", "APEH", "APEX1", "API5", "APMAP", "APOOL", "APRT", "AQR", "ARCN1", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF1", "ARID1A", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL6IP4", "ARL6IP5", "ARMC1", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC5", "AS3MT", "ASCC2", "ASCC3", "ASNA1", "ASNS", "ASPH", "ASPM", "ASRGL1", "ATAD1", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATG4B", "ATIC", "ATL2", "ATP13A1", "ATP1B3", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6V0A1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7B", "ATPAF1", "ATPIF1", "ATRX", "ATXN10", "ATXN2L", "AUP1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAP18", "BASP1", "BAZ1B", "BCAP31", "BCAS2", "BCAT2", "BCCIP", "BCL2L12", "BCL2L13", "BCLAF1", "BIRC6", "BLMH", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOP1", "BPNT1", "BRD2", "BRI3BP", "BRIX1", "BSG", "BTF3", "BUB3", "BUD31", "BYSL", "BZW1", "BZW2", "C11orf58", "C12orf43", "C12orf73", "C15orf39", "C19orf25", "C19orf70", "C1QBP", "C1orf123", "C1orf35", "C20orf27", "C2CD2", "C2CD5", "C2orf49", "C5orf15", "CAB39", "CACUL1", "CACYBP", "CAD", "CALD1", "CALR", "CALU", "CAND1", "CANX", "CAP1", "CAPN1", "CAPRIN1", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CASP2", "CASP3", "CASP6", "CAST", "CBFB", "CBR1", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC124", "CCDC47", "CCDC6", "CCDC86", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT6A", "CCT7", "CCT8", "CD276", "CD2AP", "CD2BP2", "CD47", "CD81", "CDC123", "CDC27", "CDC37", "CDC42", "CDC45", "CDC5L", "CDC73", "CDCA8", "CDK1", "CDK13", "CDK2", "CDK4", "CDK5RAP3", "CDK6", "CDKN2AIP", "CDS2", "CDV3", "CEBPZ", "CELF1", "CELF2", "CENPV", "CEP170", "CEP55", "CERS2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHEK2", "CHID1", "CHKA", "CHMP2A", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CIZ1", "CKAP2", "CKAP5", "CKB", "CLASP2", "CLCN3", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLNS1A", "CLP1", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTA", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNOT1", "CNOT11", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COG7", "COIL", "COL4A3BP", "COLGALT1", "COMMD10", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COTL1", "COX4I1", "COX5B", "COX6C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF6", "CPSF7", "CPT2", "CPVL", "CRK", "CRKL", "CRTAP", "CRYZL1", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL4B", "CUL5", "CUTA", "CWC22", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DCAF13", "DCAF7", "DCAKD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DHFR", "DHPS", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX40", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB6", "DNAJC1", "DNAJC11", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOHH", "DPF2", "DPH2", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DRG1", "DRG2", "DSG2", "DSP", "DST", "DTL", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFL1", "EFTUD2", "EHD1", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC8", "EMD", "EMG1", "EML4", "ENDOD1", "ENO1", "ENOPH1", "ENSA", "ENY2", "EPB41", "EPB41L2", "EPB41L3", "EPHX2", "EPPK1", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERC1", "ERCC2", "ERCC6L", "ERH", "ERI1", "ERLIN2", "ERP29", "ESD", "ESS2", "ESYT1", "ESYT2", "ETFA", "ETFB", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC4", "EXOC6", "EXOC7", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC7", "EXOSC8", "EXOSC9", "EYA3", "EZR", "F11R", "FABP5", "FAF1", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120A", "FAM120B", "FAM136A", "FAM162A", "FAM177A1", "FAM208A", "FAM3C", "FAM49B", "FAM8A1", "FAM91A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FBL", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FLCN", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNBP4", "FNDC3A", "FNTA", "FNTB", "FOXC1", "FOXRED1", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT2", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLM", "GCN1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GHITM", "GIGYF2", "GINS1", "GINS2", "GINS3", "GINS4", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX5", "GLS", "GLTP", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNE", "GNG12", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GOLGA3", "GOLGB1", "GOLIM4", "GOPC", "GOT1", "GPAA1", "GPD2", "GPI", "GPKOW", "GPR107", "GPR108", "GPS1", "GPT2", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2E1", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C5", "GTPBP1", "GTPBP4", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDGFL2", "HDHD2", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEBP1", "HECTD1", "HELLS", "HELZ", "HERC2", "HEXA", "HGH1", "HGS", "HIBCH", "HINT2", "HIST1H1C", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLCS", "HLTF", "HM13", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCS1", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HP1BP3", "HPRT1", "HS1BP3", "HSD17B11", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPH1", "HTATSF1", "HUWE1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IFIT5", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "ILF2", "ILF3", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPAD1", "IMPDH2", "INA", "INCENP", "INF2", "INTS3", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IRF2BPL", "ISCU", "ISOC1", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPK1", "IVD", "JPT2", "JUP", "KARS", "KAT7", "KCTD12", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM3B", "KHDRBS1", "KHSRP", "KIAA0368", "KIF11", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KLC1", "KLC2", "KLC4", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LAMTOR1", "LAMTOR2", "LANCL1", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDHA", "LDHB", "LEMD3", "LENG8", "LETM1", "LGALS3", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LMAN1", "LMNA", "LMNB1", "LMNB2", "LONP1", "LPCAT1", "LRBA", "LRCH2", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC59", "LRWD1", "LSG1", "LSM12", "LSM14A", "LSM14B", "LSM2", "LSM6", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LZTFL1", "LZTS2", "MACF1", "MAGED2", "MAK16", "MANF", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MCAT", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED17", "MED25", "MEPCE", "MESD", "METTL1", "METTL13", "MFF", "MFN2", "MFSD10", "MGEA5", "MGST2", "MGST3", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MIPEP", "MKI67", "MMAB", "MMS19", "MOGS", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP2", "MPRIP", "MPST", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL19", "MRPL2", "MRPL21", "MRPL28", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL44", "MRPL46", "MRPL50", "MRPL58", "MRPL9", "MRPS10", "MRPS15", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH2", "MTDH", "MTFP1", "MTHFD1L", "MTHFD2", "MTIF2", "MTOR", "MTPAP", "MTPN", "MTX1", "MTX2", "MTX3", "MUT", "MVD", "MVK", "MXRA7", "MYBBP1A", "MYG1", "MYH10", "MYH9", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA25", "NAA35", "NAA40", "NAA50", "NADK2", "NAE1", "NAGK", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPH", "NCAPH2", "NCBP1", "NCDN", "NCK1", "NCKAP1", "NCL", "NCLN", "NCOA5", "NCSTN", "NDC1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF4", "NDUFB11", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4", "NEFL", "NEFM", "NELFA", "NELFCD", "NELFE", "NEMF", "NES", "NFS1", "NHLRC2", "NIFK", "NIP7", "NIPA2", "NIPSNAP2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NME1", "NME2", "NMT1", "NNT", "NOC2L", "NOC3L", "NOC4L", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOSIP", "NOVA2", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NSA2", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSMCE2", "NSUN2", "NSUN5", "NSUN6", "NT5C3A", "NT5DC1", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDT1", "NUDT16L1", "NUDT21", "NUDT5", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP188", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCRL", "ODR4", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC3", "OSBP", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OTULIN", "OXA1L", "OXSR1", "P3H1", "P4HA1", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAK1IP1", "PAK2", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PASK", "PATL1", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDS5A", "PDS5B", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PGAM1", "PGAM5", "PGD", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF2", "PHF3", "PHF5A", "PHF6", "PHGDH", "PHIP", "PI4K2A", "PICALM", "PIGU", "PIH1D1", "PIK3C2A", "PIN1", "PIN4", "PINX1", "PIR", "PISD", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN2", "PLA2G15", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLOD1", "PLOD2", "PLRG1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPO", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLRMT", "POP1", "POR", "PPA1", "PPA2", "PPAT", "PPHLN1", "PPIB", "PPID", "PPIF", "PPIL1", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R1", "PPP5C", "PPT1", "PPT2", "PQBP1", "PRAF2", "PRC1", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PRIM2", "PRKAA1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF39", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA4", "PSMA5", "PSMA6", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSPC1", "PTBP1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR2", "PTPA", "PTPN1", "PTPN11", "PTRH2", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PWP1", "PWP2", "PXN", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB13", "RAB14", "RAB1A", "RAB24", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RABGAP1", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD51AP1", "RAE1", "RAI14", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP1GDS1", "RAPGEF2", "RARS", "RAVER1", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM8A", "RBMX", "RBMXL1", "RBP1", "RCC1", "RCL1", "RCN1", "RCN2", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "REEP5", "RER1", "RETREG2", "RETREG3", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFLNB", "RHOA", "RHOT2", "RIF1", "RINT1", "RMDN1", "RMDN3", "RNASEH2A", "RNASEH2B", "RNF114", "RNF14", "RNF40", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP3", "RPF2", "RPL10", "RPL10A", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL32", "RPL34", "RPL35", "RPL36", "RPL36A", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPSA", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSBN1", "RSF1", "RSL1D1", "RSU1", "RTCB", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMHD1", "SAMM50", "SAP18", "SAP30BP", "SAR1A", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCML2", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDCBP", "SDE2", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC16A", "SEC23A", "SEC23IP", "SEC24A", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC63", "SENP3", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD7", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN4", "SGPL1", "SGTA", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIN3A", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC30A5", "SLC35B2", "SLC35F2", "SLC3A2", "SLC4A1AP", "SLC9A3R1", "SLFN11", "SLIRP", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SMYD3", "SMYD5", "SNAP23", "SNAP29", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD2", "SNRPD3", "SNW1", "SNX1", "SNX2", "SNX27", "SNX5", "SNX6", "SOAT1", "SOD2", "SON", "SORD", "SPAG9", "SPART", "SPATA5L1", "SPC24", "SPC25", "SPCS2", "SPECC1L", "SPEN", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SQLE", "SRBD1", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRPK1", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STIP1", "STK4", "STMN1", "STOML2", "STRAP", "STRN", "STT3B", "STUB1", "STX10", "STX12", "STX17", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SULT2A1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACC3", "TACO1", "TAF15", "TAGLN2", "TALDO1", "TAMM41", "TARDBP", "TARS", "TARS2", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TDP2", "TDRKH", "TECR", "TELO2", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFG", "TFIP11", "TFRC", "TGOLN2", "THOC1", "THOC3", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "TIA1", "TIAL1", "TIMELESS", "TIMM13", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TJP1", "TKT", "TLN1", "TM9SF3", "TMA16", "TMCO1", "TMED10", "TMED2", "TMEM109", "TMEM11", "TMEM126A", "TMEM192", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM87A", "TMEM97", "TMOD3", "TMPPE", "TMX1", "TMX2", "TMX4", "TNPO1", "TNPO2", "TOE1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOX4", "TP53", "TP53BP1", "TPD52", "TPD52L2", "TPI1", "TPM3", "TPM4", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRIM21", "TRIM25", "TRIM27", "TRIM28", "TRIP12", "TRIP13", "TRMT10C", "TRMT11", "TRMT112", "TRMT2A", "TRMT6", "TROVE2", "TRUB1", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPYL1", "TSR1", "TSTA3", "TTC1", "TTC19", "TTC37", "TTC38", "TTC4", "TTI1", "TTK", "TTLL12", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUFM", "TWF1", "TWF2", "TWISTNB", "TXLNA", "TXLNG", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE2V1", "UBE3C", "UBE4A", "UBLCP1", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UFSP2", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "UROD", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP28", "USP33", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VBP1", "VCL", "VCP", "VDAC2", "VDAC3", "VEZT", "VIM", "VPS26A", "VPS29", "VPS33A", "VPS35", "VPS4A", "VPS51", "VPS53", "VRK1", "VRK3", "WAPL", "WARS", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR18", "WDR3", "WDR33", "WDR36", "WDR41", "WDR46", "WDR5", "WDR6", "WDR61", "WDR70", "WDR77", "WDR82", "WIPI2", "WIZ", "WRAP53", "WTAP", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YKT6", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAQ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZDHHC13", "ZFR", "ZFYVE16", "ZMYM4", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF622", "ZNF638", "ZNF687", "ZPR1", "ZRANB2", "ZW10", "ZYX"], "leading_proteins": ["ABCB7", "ABCC1", "ABCC4", "ABHD10", "ACOT13", "ACTN2", "ADPGK", "AKT1", "ALDH3A2", "ANKLE2", "ANLN", "AP1B1", "ARFIP2", "ARL6IP5", "ASPM", "ATAD1", "ATAD3A", "ATAD5", "ATP5I", "ATPAF1", "ATPIF1", "BAIAP2", "BASP1", "BCAS2", "BUD31", "C12orf73", "C19orf70", "CASP3", "CCDC47", "CDCA8", "CDS2", "CENPV", "CEP55", "CERS2", "CHKA", "CKAP2", "CLGN", "CLNS1A", "CLPTM1", "CLPTM1L", "COA3", "COL4A3BP", "COX4I1", "COX6C", "CPOX", "CPT2", "CXADR", "CYB5B", "CYP20A1", "CYP51A1", "DDRGK1", "DERL1", "DERL2", "DHFR", "DHX36", "DIAPH3", "DIP2B", "DNAJA3", "DNAJC3", "DSP", "DYNC1LI2", "EARS2", "EDRF1", "ELOC", "ENSA", "EPPK1", "ERAP1", "ERCC6L", "F11R", "FABP5", "FDXR", "FH", "FKBP7", "FKBP8", "FKBP9", "FNTB", "GADD45GIP1", "GCC2", "GLO1", "GNAI2", "GOLGB1", "GOLIM4", "GPR108", "GPT2", "H1F0", "HINT2", "HMOX1", "HSPB1", "IMPAD1", "ISOC1", "JUP", "KIF1A", "KIF23", "KIF2A", "KIF2C", "KTN1", "LAP3", "LCLAT1", "LETM1", "LIG1", "LRPAP1", "MACF1", "MANF", "MAP3K7", "MARC1", "MARK2", "MCCC2", "MCU", "MEPCE", "MFN2", "MIPEP", "MOSPD2", "MRPL14", "MRPL28", "MRPL38", "MRPL40", "MRPL9", "MRPS10", "MRPS23", "MRPS28", "MRPS5", "MRRF", "MSMO1", "MSN", "MTDH", "MTFP1", "MTX1", "MTX3", "MUT", "MXRA7", "NAMPT", "NDUFA11", "NDUFA8", "NDUFB11", "NDUFS3", "NECAP2", "NEFL", "NOL8", "NPTN", "NT5C3A", "NUBPL", "NUCB2", "OCRL", "ODR4", "OXA1L", "PAFAH1B3", "PAIP1", "PCK2", "PGRMC2", "PIN4", "POLE", "PPM1F", "PRAF2", "PRC1", "PSMD10", "PSMG1", "PTRH2", "QRSL1", "RAB1A", "RAB3B", "REXO2", "RFLNB", "RPL10A", "RPL23A", "RPL32", "RPL35", "RPL36", "RPL9", "RPLP2", "RPN1", "RPN2", "RPS14", "RPS15", "RPS16", "RPS2", "RPS6", "RPS7", "RPS8", "RTN1", "RTN3", "SCAMP1", "SCARB1", "SCD", "SFXN4", "SGPL1", "SLC25A10", "SLC25A26", "SLC25A32", "SLC30A5", "SLC35F2", "SLC9A3R1", "SNX1", "SOAT1", "SOD2", "SRBD1", "SSBP1", "SSR1", "STT3B", "SURF4", "SYNGR2", "SYNJ2BP", "TDRKH", "TIMM13", "TIMM17A", "TIMM17B", "TIMM23", "TMEM230", "TMEM87A", "TMPPE", "TOMM22", "TRABD", "TRMT6", "TSN", "TSPAN3", "TUBB2A", "TUBB4A", "TUBB4B", "TXLNA", "UBA3", "UBE2S", "UGP2", "UQCRQ", "USP33", "UTP15", "VARS2", "YKT6", "YME1L1", "YRDC", "ZADH2", "ZDHHC13", "ZNF622"]} \ No newline at end of file