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interpro_active_site/advanced/idx2term.json

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+{}

interpro_active_site/basic/idx2term.json

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+{}

interpro_active_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:f8914ee426eab48612f01610b60c6664c916232376576c2ba9106ef4dc48288e
+size 67920

interpro_active_site/df_merge.tsv

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+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_active_site/metrics.json

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+{
+    "type_of_task": "ranksum",
+    "signature_size": 2773,
+    "annotations_size": 56,
+    "title": "Average number of proteins per term",
+    "value": 2.392857142857143
+}

interpro_active_site/paths.json

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+{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C322/C322_val_log2fc"}

interpro_active_site/result.tsv

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+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size

interpro_active_site/selections.json

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+{"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase,  active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT1", "AKT2", "APEH", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "BLMH", "CAPN1", "CASP2", "CASP3", "CASP6", "CDK1", "CDK13", "CDK2", "CDK4", "CDK6", "CHEK2", "CHUK", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSB", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLUD1", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "IGF1R", "LDHA", "LDHB", "LONP1", "MAP2K1", "MAP2K2", "MAP3K7", "MAPK1", "MAPK3", "MARK2", "MDH1", "MDH2", "MTMR6", "NEK9", "NME1", "NME2", "PAK2", "PASK", "PBK", "PGAM1", "PKM", "PKMYT1", "PKN2", "PLK1", "PREP", "PRKAA1", "PRKACA", "PRPF4B", "PTK7", "PTPN1", "PTPN11", "RNASET2", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SUCLG1", "TALDO1", "TOP1", "TPI1", "TPP2", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UMPS", "UNG", "VRK1"], "leading_proteins": []}

interpro_binding_site/advanced/idx2term.json

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+{}

interpro_binding_site/basic/idx2term.json

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+{"0": "EF-Hand 1, calcium-binding site [IPR018247]"}

interpro_binding_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:a1c833d6271eb4a7d35a2a817f92b1e297fbceaa56a19519a48c93fef4b4797d
+size 64636

interpro_binding_site/df_merge.tsv

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+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_binding_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2773,
+    "annotations_size": 28,
+    "title": "Average number of proteins per term",
+    "value": 4.285714285714286
+}

interpro_binding_site/paths.json

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+{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C322/C322_val_log2fc"}

interpro_binding_site/result.tsv

@@ -0,0 +1,4 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+EF-Hand 1, calcium-binding site [IPR018247]	0.4589133225167561	1.647838485131362	0.099385819334735	0.9466559647895738	0.2140617647209677	31	Q6NUK1,Q9Y680,P80303,P43304,Q8IXI1,O95302,Q14257,O95202,Q9NWM8,Q02818,O43852,Q9UBV8	12
+Peptidase M16, zinc-binding site [IPR001431]	0.6485845443619701	1.116793935034901	0.2640824426495725	0.9998132689231584	0.4107949107882238	5	Q10713,P22695	2
+Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]	0.4243955250811871	0.057042351375192	0.9545114585248466	1.0	0.9849487233468364	2	P34896	1

interpro_binding_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]"], "available_proteins": ["ACACA", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT1", "AKT2", "APEX1", "ASPM", "BPNT1", "CALU", "CAPN1", "CDK1", "CDK13", "CDK2", "CDK4", "CDK6", "CHUK", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DLAT", "DLST", "DST", "EHD1", "EIF2AK2", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "GCAT", "GOT1", "GOT2", "GPD2", "HK1", "HK2", "IDE", "IGF1R", "ILKAP", "IQGAP1", "LETM1", "MACF1", "MAP2K1", "MAP2K2", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MARK2", "MCCC1", "MICU1", "MYH10", "MYH9", "MYO1B", "MYO1C", "MYO1D", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXSR1", "PA2G4", "PAK2", "PASK", "PC", "PCCA", "PDCD6", "PEF1", "PGD", "PKMYT1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1F", "PPM1G", "PRKAA1", "PRKACA", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "RHOT1", "RHOT2", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "STK4", "TKT", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "UQCRC2", "VRK1"], "leading_proteins": ["CALU", "FKBP14", "FKBP7", "FKBP9", "GPD2", "LETM1", "NUCB1", "NUCB2", "PEF1", "PMPCA", "RCN2", "RHOT2", "SHMT1", "SLC25A24", "UQCRC2"]}

interpro_conserved_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Proteasome beta-type subunit, conserved site [IPR016050]"}

interpro_conserved_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Proteasome beta-type subunit, conserved site [IPR016050]"}

interpro_conserved_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:dbdddd4daa4d76f0d36227406781c6cd16884c31e6515bf6ad5f680b2a3d9379
+size 82834

interpro_conserved_site/df_merge.tsv

@@ -0,0 +1,2 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Proteasome beta-type subunit, conserved site [IPR016050]	6	8	2.5016276763855143	0.0123623858134251	3.7135922330097086	7.970873786407767	1.4913184573846054	0.1902243906475925	1.515457478026574	0.1681602725795027	1.0170822776023185	0.2455850375425174	0.015532717557002	1.0	0.0930016660897952	0.0233125205204954	6.624514437802759e-08

interpro_conserved_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2773,
+    "annotations_size": 257,
+    "title": "Average number of proteins per term",
+    "value": 2.5525291828793772
+}

interpro_conserved_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C322/C322_val_log2fc"}

interpro_conserved_site/result.tsv

@@ -0,0 +1,27 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Proteasome beta-type subunit, conserved site [IPR016050]	0.8345352196993657	2.5016276763855143	0.0123623858134251	0.9591126679964443	0.1017510051774825	8	P28072,P49721,P49720,P28070,P25789,P20618	6
+Intermediate filament protein, conserved site [IPR018039]	0.6987210241205657	1.8609768780713132	0.0627474419920366	0.9999999415001112	0.2337114868399046	8	P08670,Q16352,P07197	3
+Tetraspanin, conserved site [IPR018503]	0.9720198146848926	1.6481497363841964	0.0993219482447775	0.9999999999978896	0.299307286952682	3	O43657	1
+Haem oxygenase conserved site [IPR018207]	0.8960664020209284	1.5600056679939465	0.1187585417658414	0.9999999999999922	0.3353950025694642	2	P30519	1
+Syntaxin/epimorphin, conserved site [IPR006012]	0.6138595220530921	1.38095495705092	0.1672928105267928	1.0	0.3838772527266584	7	Q86Y82,Q9P2W9,Q13190	3
+ABC transporter-like, conserved site [IPR017871]	0.5409524746768823	1.2316408103984662	0.2180832890935979	1.0	0.4556699617646721	10	O75027,P33527	2
+Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]	0.8111913357400702	1.0376061779979724	0.2994534405063143	1.0	0.5658789280156086	3	Q8WWV3,Q8N4Q0	2
+Mini-chromosome maintenance, conserved site [IPR018525]	0.5683986342456187	1.0311060883406995	0.3024910730257635	1.0	0.5674467574278921	6	P25205,Q14566	2
+Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]	0.7657885239985538	1.0149366963315851	0.3101360042486663	1.0	0.5693210935136231	2	P04439	1
+Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]	0.7695659487918998	0.8830043506674564	0.3772339208625843	1.0	0.6420471368323455	3	P27361	1
+Thioredoxin, conserved site [IPR017937]	0.4456160823341233	0.7785777033116638	0.4362285175783245	1.0	0.6671675970436434	11	O43396,Q8IXB1,Q9H3N1,Q9H1E5	4
+Heat shock protein Hsp90, conserved site [IPR019805]	0.7296028880866399	0.7386922656863119	0.4600938833274233	1.0	0.6898813571149925	3	P07900,P14625	2
+Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]	0.6578852399855588	0.5946329366129969	0.5520888587997914	1.0	0.7507240037647956	2	Q07812	1
+Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]	0.6578852399855588	0.5946329366129969	0.5520888587997914	1.0	0.7507240037647956	2	Q07812	1
+Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]	0.6578852399855588	0.5946329366129969	0.5520888587997914	1.0	0.7507240037647956	2	Q07812	1
+Ras GTPase-activating protein, conserved site [IPR023152]	0.5788523998556396	0.3374908242447582	0.7357469280337421	1.0	0.8772893623088469	2	P20936	1
+Phosphorylase pyridoxal-phosphate attachment site [IPR035090]	0.5694695055936401	0.3113436145162265	0.7555394141253762	1.0	0.8866375773069484	2	P06737	1
+Clathrin adaptor, mu subunit, conserved site [IPR018240]	0.5487737761371378	0.2018549330865847	0.8400301349556973	1.0	0.957881130384184	3	Q9Y2T2	1
+Ribosomal protein S5, N-terminal, conserved site [IPR018192]	0.5185853482497192	0.1893820698487529	0.8497933763719607	1.0	0.957881130384184	2	P15880	1
+Ribosomal protein S2, conserved site [IPR018130]	0.4608444604835681	0.0943587818962269	0.9248241569496044	1.0	1.0	2	Q9Y399	1
+DNA-directed DNA polymerase, family B, conserved site [IPR017964]	0.4471309996391072	0.0784206393133984	0.9374934562886984	1.0	1.0	2	P09884	1
+HMG box A DNA-binding domain, conserved site [IPR017967]	0.4599277978339295	0.057182021276845	0.9544001996670176	1.0	1.0	3	O15347,P09429	2
+Vinculin, conserved site [IPR000633]	0.3984121255864173	0.0394185042865415	0.968556727087038	1.0	1.0	2	P18206	1
+Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]	0.3857813063875767	0.0330843413237392	0.9736073297281318	1.0	1.0	2	P29692	1
+DNA ligase, ATP-dependent, conserved site [IPR016059]	0.3832551425478112	0.031970989286889	0.9744951862611156	1.0	1.0	2	P18858	1
+RNA polymerase, beta subunit, conserved site [IPR007121]	0.3655719956694249	0.0254459616748466	0.9796992508474088	1.0	1.0	2	P30876	1

interpro_conserved_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Bromodomain, conserved site [IPR018359]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific,  conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Heavy-metal-associated, conserved site [IPR017969]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Pyridoxamine 5'-phosphate oxidase, conserved site [IPR019740]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P,  conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class II, conserved site [IPR002011]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB10", "ABCB7", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP3M1", "APEX1", "ARHGEF7", "ATAD1", "ATP5C1", "ATP5O", "ATP7B", "BAG6", "BAK1", "BAX", "BAZ1A", "BAZ1B", "BCAT2", "BCS1L", "BOP1", "BPNT1", "BRD2", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZB", "CASK", "CBR1", "CBX1", "CBX3", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD81", "CDKAL1", "CHAF1B", "CHD1", "CHD1L", "CHD4", "CLGN", "CMPK1", "CNDP2", "COPA", "COPZ1", "CORO1C", "CPOX", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX40", "DHX8", "DHX9", "DIDO1", "DIS3", "DIS3L2", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC9", "DNM1", "DNM1L", "DNM2", "DNMT1", "DRG1", "DRG2", "DSG2", "DST", "DTL", "DTYMK", "DYNLL1", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A3", "EIF4E", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPRS", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXC1", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLO1", "GMPPA", "GMPPB", "GNPDA1", "GNS", "GPI", "GRHPR", "GRWD1", "GSPT1", "GTF3C2", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IGF1R", "ILVBL", "IMPAD1", "IMPDH2", "INA", "IQGAP1", "IVD", "KDSR", "KIF11", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "LAMP1", "LARS", "LARS2", "LBR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MAPK3", "MARS", "MAT2A", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGST2", "MID1", "MIF", "MPI", "MPP2", "MPP6", "MPST", "MRPL3", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "MVK", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFV1", "NEFL", "NEFM", "NES", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD2", "NSF", "NSUN6", "NUBP2", "NUBPL", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF2", "PHF3", "PHGDH", "PHIP", "PIK3C2A", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PNP", "PNPLA6", "PNPO", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2E", "PPIB", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RASA1", "RCL1", "RDH13", "RDX", "RIDA", "RNF114", "RNF14", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RTN4IP1", "S100A10", "S100A11", "SART1", "SBDS", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC27A4", "SMARCA4", "SMS", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STRN", "STX10", "STX12", "STX17", "STX18", "STX4", "STX5", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE2", "TBL3", "TCP1", "TK1", "TLN1", "TMX1", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM21", "TRIM25", "TRIM27", "TRIM28", "TRIP13", "TRMT11", "TSFM", "TSPAN3", "TSPAN6", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UHRF1", "USP10", "USP11", "USP14", "USP19", "USP28", "USP33", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "WARS", "WDHD1", "WDR1", "WDR18", "WDR3", "WDR36", "WDR41", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2"], "leading_proteins": ["ABCB7", "ABCC1", "AP3M1", "BAX", "DNAJC10", "EEF1D", "HLA-A", "HMGB1", "HMGB3", "HMOX2", "HSP90AA1", "HSP90B1", "INA", "LIG1", "MAPK3", "MCM3", "MCM6", "MRPS2", "NEFM", "POLA1", "POLR2B", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB6", "PYGL", "RASA1", "RPS2", "RTN4IP1", "STX12", "STX18", "STX5", "TMX1", "TMX4", "TSPAN6", "TXNL1", "VCL", "VIM", "ZADH2"]}

interpro_domain/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Cytochrome b5-like heme/steroid binding domain [IPR001199]", "1": "RNA recognition motif domain [IPR000504]", "2": "FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]", "3": "EF-hand domain [IPR002048]"}

interpro_domain/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Cytochrome b5-like heme/steroid binding domain [IPR001199]", "1": "RNA recognition motif domain [IPR000504]", "2": "FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]", "3": "EF-hand domain [IPR002048]", "4": "Immunoglobulin-like domain [IPR007110]", "5": "Importin-beta, N-terminal domain [IPR001494]", "6": "K Homology domain, type 1 [IPR004088]", "7": "K Homology domain [IPR004087]", "8": "Proteasome component (PCI) domain [IPR000717]", "9": "DnaJ domain [IPR001623]"}

interpro_domain/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:14564ceb7601d2ff9b82745f254397e1dfb23575a722cbf854e2706726edd65d
+size 300090

interpro_domain/df_merge.tsv

@@ -0,0 +1,7 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	5	7	2.6830001283823397	0.0072964962326285	2.813106796116505	6.104368932038835	1.6405397264547834	0.1100883340733615	1.2852875686886795	0.8042848477475721	1.100790504333474	0.1612592696854457	1.9564254331529583e-06	0.0015075035399645	5.850350500572073e-08	1.5938034825404938e-07	9.354890231096924e-06
+RNA recognition motif domain [IPR000504]	37	108	2.4283794858108863	0.0151664646612648	39.713592233009706	116.0	0.2316956716939257	0.5316884276370477	13.873754985119357	5.729331786381952	1.713447249572458	0.3950212299678106	0.0212497837349266	1.0	1.0	8.627920449592083e-05	4.869825615470487e-09
+FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]	5	11	2.204585444474137	0.0274831980816832	3.1262135922330097	10.111650485436892	0.9686720267359892	0.3700536707457866	1.7316562118191232	1.203619216216406	0.9607394322697528	0.3108814801432357	0.2271647199618277	0.0619434524836269	0.1191939669275513	0.0033939033653995	1.665940864684324e-05
+P-type ATPase, haloacid dehalogenase domain [IPR044492]	4	6	2.1662432833493197	0.030292601210458	2.941747572815534	6.145631067961165	0.9567723497044874	0.2732808833570771	1.8358630293390923	1.459204245106796	1.2102525517005158	0.2943240638910574	0.3535661219065057	0.1026081339138497	0.1933613304033528	0.4185863086244521	0.0035606647558243
+EF-hand domain [IPR002048]	18	38	2.156367273192719	0.0310549980393994	12.385922330097088	43.512135922330096	1.0171858714399242	0.3947118087831401	4.608360476919044	4.087317384177653	1.201458704248258	0.3652478399429377	0.0137221300177981	0.086158736226278	0.0161267578272062	0.0108922370163757	1.3181039844505391e-06
+Zinc finger, RanBP2-type [IPR001876]	3	8	1.9924577669453731	0.0463208545767706	3.2742718446601944	8.616504854368932	0.6239078002715212	0.4100405386528319	1.463145369641179	0.7330740021954685	1.0299872364022182	0.3121093098016552	0.0629928899780233	1.0	1.0	0.0136772183990335	0.0172333771485565

interpro_domain/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2773,
+    "annotations_size": 2334,
+    "title": "Average number of proteins per term",
+    "value": 2.0976863753213366
+}

interpro_domain/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C322/C322_val_log2fc"}

interpro_domain/result.tsv

@@ -0,0 +1,179 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	0.8930828592308672	2.6830001283823393	0.0072964962326285	0.9999999622566236	0.105747529544541	7	O43169,Q9UMX5,Q8WUJ1,O00264,O15173	5
+RNA recognition motif domain [IPR000504]	0.3985031402167518	2.4283794858108863	0.0151664646612648	0.9999999999999996	0.1258947901815265	108	Q9Y6M1,O43390,Q8WXF1,P26368,Q14011,Q99729,Q96E39,Q96PK6,P43243,P31943,Q13595,O60506,O14979,Q13151,P22626,P55795,P23246,Q9BWF3,Q07955,Q01085,P38159,P98179,Q13242,P51991,Q15233,P98175,P52597,Q14103,Q01844,Q76FK4,Q9UHX1,P23588,P62995,Q92804,P35637,P07910,P31942	37
+FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]	0.6984673204289725	2.204585444474137	0.0274831980816832	1.0	0.1494597030669396	11	O00170,Q9Y680,O95302,Q9NWM8,P62942	5
+P-type ATPase, haloacid dehalogenase domain [IPR044492]	0.8136485164444344	2.1662432833493193	0.030292601210458	1.0	0.1581721056492374	6	P16615,P05023,Q9HD20,P35670	4
+EF-hand domain [IPR002048]	0.4993790103169664	2.156367273192719	0.0310549980393994	1.0	0.1589165917830871	38	Q6NUK1,Q9Y680,P35609,O75071,P80303,Q8NF37,Q9UJS0,Q8IYU8,P43304,Q8IXI1,O95302,Q14257,O95202,Q96AY3,Q02818,Q9NWM8,O43852,Q9UBV8	18
+Zinc finger, RanBP2-type [IPR001876]	0.7257854024547568	1.9924577669453736	0.0463208545767706	1.0	0.1941580476538532	8	Q01844,Q92804,P35637	3
+EXPERA domain [IPR033118]	0.973655719956694	1.8850533856564071	0.0594226305632283	1.0	0.2181152932738808	2	Q5BJF2	1
+Intermediate filament, rod domain [IPR039008]	0.6987210241205657	1.8609768780713132	0.0627474419920366	1.0	0.2256587513242118	8	P08670,Q16352,P07197	3
+TRAM/LAG1/CLN8 homology domain [IPR006634]	0.9599422591122334	1.827917657794109	0.0675619105371574	1.0	0.2312357380780832	2	Q15629	1
+Peptidase M16, C-terminal [IPR007863]	0.695036757453996	1.7780456960350284	0.0753963501274286	1.0	0.2469376419473726	7	Q5JRX3,Q10713,P22695	3
+Peptidase M16, N-terminal [IPR011765]	0.695036757453996	1.7780456960350284	0.0753963501274286	1.0	0.2469376419473726	7	Q5JRX3,Q10713,P22695	3
+ABC transporter type 1, transmembrane domain [IPR011527]	0.7238727033160036	1.762512656104799	0.0779827199568614	1.0	0.2496730704791696	6	O75027,P33527	2
+Proteasome alpha-subunit, N-terminal domain [IPR000426]	0.6906955909763458	1.757153598958246	0.0788916318583712	1.0	0.2507379071747392	7	P60900,P25787	2
+Immunoglobulin-like domain [IPR007110]	0.615629132076162	1.7545712107619371	0.0793326794296467	1.0	0.2508621180671939	11	Q5ZPR3,P78310,P04439,P10321,P01889,P35613,Q9Y639	7
+Importin-beta, N-terminal domain [IPR001494]	0.5612109932876271	1.7523889122263163	0.0797069566936954	1.0	0.2508621180671939	14	O15397,Q96P70,O43592,P55060,Q92973,Q14974,O00410,O14787,O95373	9
+Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]	0.9335979790689284	1.717725554728388	0.0858466858882609	1.0	0.2630426162596651	2	P13674	1
+Fatty acid hydroxylase [IPR006694]	0.9325153374233126	1.713186456712504	0.0866782423982199	1.0	0.2644536179835887	2	O75845	1
+Acyl-CoA oxidase, C-terminal [IPR002655]	0.9321544568747736	1.7116732563726738	0.08695689976255	1.0	0.2649574465349762	2	O15254	1
+Reticulon [IPR003388]	0.8960001720668525	1.69885810665247	0.0893459221121713	1.0	0.2681216769849518	4	Q16799,O95197	2
+GMP phosphodiesterase, delta subunit [IPR008015]	0.9841155234657036	1.6939050481495548	0.0902833275465906	1.0	0.2681216769849518	3	O43924,A6NIH7	2
+RBM3/CIRBP, RNA recognition motif [IPR034278]	0.920606279321544	1.6632091759807064	0.0962705714996396	1.0	0.2770598198275697	2	Q14011	1
+MENTAL domain [IPR019498]	0.919884518224467	1.660177655157426	0.0968787184287855	1.0	0.2772685890210748	2	O95772	1
+RNA recognition motif domain, eukaryote [IPR003954]	0.572770897694941	1.607320393571842	0.1079841028935493	1.0	0.298619545205621	12	Q14011,P38159,Q96E39,Q9UHX1	4
+Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]	0.9054492962829296	1.5994943712626184	0.1097107983026557	1.0	0.301584783821399	2	O60506	1
+Intermediate filament head, DNA-binding domain [IPR006821]	0.8598772119898871	1.5567335997160785	0.1195337478364597	1.0	0.3111447568907469	4	P08670,Q16352,P07197	3
+Peptidase M1, membrane alanine aminopeptidase [IPR014782]	0.669619169483732	1.5107383054571843	0.1308551387912992	1.0	0.3252565430659133	6	Q9NZ08,Q9UIQ6,P09960,P55786	4
+Aminopeptidase N-like , N-terminal domain [IPR045357]	0.669619169483732	1.5107383054571843	0.1308551387912992	1.0	0.3252565430659133	6	Q9NZ08,Q9UIQ6,P09960,P55786	4
+CTP synthase, N-terminal [IPR017456]	0.8816311800793939	1.499209863421524	0.1338191970339406	1.0	0.330082998388637	2	Q9NRF8	1
+CTP synthase GATase domain [IPR033828]	0.8816311800793939	1.499209863421524	0.1338191970339406	1.0	0.330082998388637	2	Q9NRF8	1
+LEM domain [IPR003887]	0.7337700061591514	1.4869009782189635	0.1370409658744584	1.0	0.333528273567243	5	P50402,Q86XL3,P42167	3
+Zinc finger C2H2 AKAP95-type [IPR034736]	0.8776614940454714	1.482485832122311	0.1382110706497579	1.0	0.3346034907022998	2	Q5BKZ1	1
+Peptidase M28 [IPR007484]	0.9225021947402772	1.460039852140547	0.1442791215639465	1.0	0.345382020236155	3	Q969V3	1
+CARG-binding factor, N-terminal [IPR012956]	0.869361241429085	1.4475161798797072	0.1477524081832077	1.0	0.350871387857647	2	Q99729	1
+Oxoglutarate/iron-dependent dioxygenase [IPR005123]	0.7202213207907986	1.4283351841871257	0.1531954053605133	1.0	0.3588976159772879	5	P13674	1
+Prolyl 4-hydroxylase, alpha subunit [IPR006620]	0.7202213207907986	1.4283351841871257	0.1531954053605133	1.0	0.3588976159772879	5	P13674	1
+GCF, C-terminal [IPR022783]	0.8617827499097759	1.415591584209779	0.1568951167458643	1.0	0.3640091475992518	2	P16383	1
+START domain [IPR002913]	0.898604535650426	1.3690014675754765	0.1709988161650117	1.0	0.3830242197016674	3	Q9NQZ5	1
+ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]	0.8498736918080116	1.365448824410201	0.1721120272235583	1.0	0.384705688533621	2	Q9NVI7	1
+RBM1CTR [IPR012604]	0.8491519307109328	1.362411324576961	0.1730681118081842	1.0	0.384705688533621	2	P38159	1
+Major facilitator superfamily domain [IPR020846]	0.8070780807553385	1.3473598146469623	0.1778643763586658	1.0	0.3923775561636351	4	P53985,Q7L0J3	2
+Tim10-like [IPR004217]	0.8451822446770119	1.3457089196498564	0.1783964086476435	1.0	0.3928086960222641	2	Q9Y5L4	1
+ERAP1-like C-terminal domain [IPR024571]	0.8030921098804955	1.33150713274525	0.183022199600118	1.0	0.3988551016495569	4	Q9NZ08,P55786	2
+Glutamine amidotransferase [IPR017926]	0.7965638812027305	1.3055378604728354	0.1917097639190355	1.0	0.4107402793496313	4	P17812,Q9NRF8	2
+Zinc finger, CHHC-type [IPR012996]	0.881588447653429	1.304181973625659	0.1921715445800331	1.0	0.4107402793496313	3	P52597,P31943	2
+Polyketide synthase, enoylreductase domain [IPR020843]	0.5956370771069244	1.2902623731266794	0.1969595763865335	1.0	0.4167757491261733	7	Q8WWV3,Q8N4Q0	2
+Metaxin, glutathione S-transferase domain [IPR033468]	0.8736651356535015	1.2740199845907123	0.2026563337249265	1.0	0.4242151416268865	3	Q13505	1
+Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564]	0.8736651356535015	1.2740199845907123	0.2026563337249265	1.0	0.4242151416268865	3	Q13505	1
+FAD-binding domain, PCMH-type [IPR016166]	0.8249729339588554	1.2608162871038615	0.2073750443485162	1.0	0.4294705887395182	2	Q15392	1
+FAD linked oxidase, N-terminal [IPR006094]	0.8249729339588554	1.2608162871038615	0.2073750443485162	1.0	0.4294705887395182	2	Q15392	1
+GRAM domain [IPR004182]	0.821003247924936	1.2441767014514866	0.2134345365947592	1.0	0.4400673219188763	2	Q969T9	1
+ABC transporter-like, ATP-binding domain [IPR003439]	0.5409524746768823	1.2316408103984662	0.2180832890935979	1.0	0.4441591594628775	10	O75027,P33527	2
+Cation-transporting P-type ATPase, C-terminal [IPR006068]	0.7774457271639488	1.2294782342801247	0.2188925535980552	1.0	0.4442567131285748	4	P05023,P16615	2
+Cation-transporting P-type ATPase, N-terminal [IPR004014]	0.7774457271639488	1.2294782342801247	0.2188925535980552	1.0	0.4442567131285748	4	P05023,P16615	2
+Exocyst complex component EXOC2/Sec5, N-terminal domain [IPR039481]	0.8159509202453943	1.223020597913676	0.2213219165677289	1.0	0.4468558419282692	2	Q96KP1	1
+Fibronectin type II domain [IPR000562]	0.8152291591483204	1.22000041538244	0.2224647174299101	1.0	0.4476143538632847	2	P11717	1
+Peptidase M41 [IPR000642]	0.803320101046552	1.1702539299510897	0.2418987957314711	1.0	0.4689300575060246	2	Q96TA2	1
+Immunoglobulin C1-set [IPR003597]	0.7580353918382086	1.1523301284877847	0.2491854409107463	1.0	0.4736146735225423	4	P10321,P01889,P04439	3
+NOPS [IPR012975]	0.8281588447653416	1.101451065640368	0.270700390806931	1.0	0.498281176845342	3	Q8WXF1,P23246	2
+NECAP, PHear domain [IPR012466]	0.7863587152652454	1.0997432329084886	0.2714440122319106	1.0	0.4984660303298814	2	Q9NVZ3	1
+JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]	0.5469142922092896	1.0940092748938186	0.273950910433578	1.0	0.5022792026331273	8	O95630,O00303	2
+Post-SET domain [IPR003616]	0.7827499097798609	1.0848029435649122	0.2780089415403912	1.0	0.5053743645470216	2	Q03164	1
+Fragile X-related 1 protein, C-terminal region 1 [IPR032172]	0.7809455070371687	1.077341957707395	0.281327524176318	1.0	0.5067392209116345	2	P51116	1
+LEM-like domain [IPR013146]	0.774088776614938	1.0490494208672023	0.294155373198125	1.0	0.5209094393356781	2	P42167	1
+MCM, AAA-lid domain [IPR041562]	0.5683986342456187	1.0311060883406995	0.3024910730257635	1.0	0.5291782590310697	6	P25205,Q14566	2
+MCM N-terminal domain [IPR027925]	0.5683986342456187	1.0311060883406995	0.3024910730257635	1.0	0.5291782590310697	6	P25205,Q14566	2
+MCM OB domain [IPR033762]	0.5683986342456187	1.0311060883406995	0.3024910730257635	1.0	0.5291782590310697	6	P25205,Q14566	2
+MCM domain [IPR001208]	0.5683986342456187	1.0311060883406995	0.3024910730257635	1.0	0.5291782590310697	6	P25205,Q14566	2
+Immunoglobulin subtype 2 [IPR003598]	0.5425885059967728	1.0247150405199097	0.3054976641274325	1.0	0.5317162923739206	7	P78310,Q9Y639,P35613	3
+Immunoglobulin subtype [IPR003599]	0.5425885059967728	1.0247150405199097	0.3054976641274325	1.0	0.5317162923739206	7	P78310,Q9Y639,P35613	3
+FAD dependent oxidoreductase [IPR006076]	0.8064502380743337	1.0198373160134455	0.3078056222895435	1.0	0.5337431815927153	3	P43304	1
+Extended PHD (ePHD) domain [IPR034732]	0.7513533020570161	0.956016847656866	0.3390637227666988	1.0	0.5628415495845239	2	Q03164	1
+Fragile X-related 1 protein, C-terminal core [IPR022034]	0.7812274368231027	0.9259604522052316	0.3544665330848968	1.0	0.570175663831943	3	P51116,Q06787	2
+Agenet-like domain [IPR008395]	0.7812274368231027	0.9259604522052316	0.3544665330848968	1.0	0.570175663831943	3	P51116,Q06787	2
+Fxr1, tudor domain [IPR041560]	0.7812274368231027	0.9259604522052316	0.3544665330848968	1.0	0.570175663831943	3	P51116,Q06787	2
+Synaptic functional regulator FMRP, KH0 domain [IPR040472]	0.7812274368231027	0.9259604522052316	0.3544665330848968	1.0	0.570175663831943	3	P51116,Q06787	2
+Protein Kinase B, pleckstrin homology domain [IPR039026]	0.7408877661493992	0.9136719680117552	0.3608892378244301	1.0	0.5744650610530017	2	P31751	1
+Tim44-like domain [IPR007379]	0.7347527968242478	0.8890136450062485	0.3739957465769601	1.0	0.5850576893502848	2	Q9BRJ2	1
+ZU5 domain [IPR000906]	0.7311439913388633	0.8745701102132036	0.3818078570263687	1.0	0.5897680597614459	2	Q12955	1
+MHC class I, alpha chain, C-terminal [IPR010579]	0.7660649819494559	0.8701729828868223	0.3842058780999799	1.0	0.5915148545417896	3	P10321,P04439	2
+MHC class I-like antigen recognition-like [IPR011161]	0.7660649819494559	0.8701729828868223	0.3842058780999799	1.0	0.5915148545417896	3	P10321,P04439	2
+MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]	0.7660649819494559	0.8701729828868223	0.3842058780999799	1.0	0.5915148545417896	3	P10321,P04439	2
+Rab-GTPase-TBC domain [IPR000195]	0.6843358704443092	0.8626022531688898	0.38835619112165	1.0	0.5951565003794689	4	Q9Y3P9	1
+Heat shock protein Hsp90, N-terminal [IPR020575]	0.6788052254264678	0.8412423386704492	0.4002121861137691	1.0	0.6003182791706536	4	P07900,P14625	2
+EF hand associated, type-1 [IPR013566]	0.7199566943341715	0.8301073010847144	0.4064781195085303	1.0	0.605708096001505	2	Q8IXI1	1
+EF hand associated, type-2 [IPR013567]	0.7199566943341715	0.8301073010847144	0.4064781195085303	1.0	0.605708096001505	2	Q8IXI1	1
+MIRO domain [IPR020860]	0.7199566943341715	0.8301073010847144	0.4064781195085303	1.0	0.605708096001505	2	Q8IXI1	1
+GINS subunit, domain A [IPR021151]	0.7549778552988313	0.829755496702047	0.4066770371490613	1.0	0.605708096001505	3	Q9BRT9	1
+CYRIA/CYRIB, Rac1 binding domain [IPR009828]	0.7185131721400178	0.8244066065096894	0.4097085622801169	1.0	0.6090826651985942	2	Q7L576	1
+Immunoglobulin V-set domain [IPR013106]	0.7514618181505981	0.8170118564658593	0.4139216524146876	1.0	0.6137821707343588	3	P78310	1
+Peptidase M24 [IPR000994]	0.5760276653425579	0.8036977996694086	0.4215715251894174	1.0	0.6200050030195969	5	Q9NQW7	1
+Peptidase M3A/M3B catalytic domain [IPR001567]	0.745487364620936	0.7954455529731389	0.4263543707800403	1.0	0.6222600685318979	3	Q9BYT8,Q99797	2
+Tudor domain [IPR002999]	0.4955796497895276	0.7904996312810523	0.4292360374726789	1.0	0.6232135426608477	7	Q14739	1
+DZF domain [IPR006561]	0.6644541925051964	0.7862011416257491	0.4317496573793917	1.0	0.6237187449751476	4	Q12905	1
+Pleckstrin homology domain, spectrin-type [IPR001605]	0.7051605918440952	0.7721073257551814	0.4400508637147839	1.0	0.6267922944828097	2	O15020	1
+Pleckstrin homology domain 9 [IPR041681]	0.7051605918440952	0.7721073257551814	0.4400508637147839	1.0	0.6267922944828097	2	O15020	1
+Rhodanese-like domain [IPR001763]	0.6993865030674802	0.7497502260482847	0.4534051514162311	1.0	0.6350301326314234	2	Q99956	1
+Exportin-2, central domain [IPR013713]	0.7303249097472896	0.7412521693842012	0.4585405568865899	1.0	0.6373557852407634	3	O15397,O95373	2
+K Homology domain, type 1 [IPR004088]	0.364062968107739	0.7033220319971188	0.4818550834724329	1.0	0.6565380997225093	24	P51114,Q96AE4,Q07666,Q9Y2W6,P61978,Q9NQT5,P51116,Q06787,Q9Y6M1,Q96PU8	10
+Alcohol dehydrogenase, N-terminal [IPR013154]	0.5514413724584798	0.7002787417131174	0.4837532450374899	1.0	0.657972071047495	5	Q8WWV3,Q8N4Q0	2
+VHS domain [IPR002014]	0.6856730422230193	0.6973480415008271	0.4855850096307779	1.0	0.6587281564634563	2	Q92783	1
+EB1, C-terminal [IPR004953]	0.6607722843738664	0.6050636214438467	0.5451367245907983	1.0	0.7029553122623886	2	Q15691	1
+Rpn11/EIF3F, C-terminal [IPR024969]	0.6039705960480117	0.5626955392364105	0.5736422223033963	1.0	0.7207806683950031	4	O00487,O00303	2
+Glycosyltransferase 2-like [IPR001173]	0.6774817971378431	0.5600531389387842	0.5754431926147916	1.0	0.7207806683950031	3	O60762	1
+Far upstream element-binding protein, C-terminal [IPR015096]	0.647419704077944	0.5573402457798382	0.5772949832671386	1.0	0.7207806683950031	2	Q96AE4	1
+FCP1 homology domain [IPR004274]	0.6470588235294057	0.5560693049619174	0.5781634777248026	1.0	0.7207806683950031	2	Q3ZCQ8	1
+ELMO domain [IPR006816]	0.6420064958498672	0.5383854622723768	0.5903109608114008	1.0	0.7297594187149414	2	Q96JJ3	1
+MPN domain [IPR037518]	0.3880089431574965	0.455846510095829	0.6485003561707123	1.0	0.7592467774839333	11	O95630,O00303	2
+UAS [IPR006577]	0.6120534103211763	0.438105017622704	0.6613101572800097	1.0	0.7669109395072481	2	Q9UNN5	1
+Peptidase C19, ubiquitin-specific peptidase, DUSP domain [IPR006615]	0.6375840244927139	0.4339011914362359	0.6643601945334119	1.0	0.7683928117150561	3	P51784	1
+Lamin tail domain [IPR001322]	0.6335740072202124	0.4218577404523631	0.6731288573032916	1.0	0.7750778258243131	3	P20700,Q03252	2
+Sorting nexin Vps5-like, C-terminal [IPR015404]	0.5613330478261295	0.4173827355752429	0.6763984807664092	1.0	0.7784586065625242	4	Q9Y5X3,O60749	2
+Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219]	0.6292418772563134	0.4089911602757833	0.6825461483134172	1.0	0.782307476045206	3	O75116,Q92974	2
+Chromo shadow domain [IPR008251]	0.6263537906137142	0.4004985570098414	0.6887893460869574	1.0	0.7872188061965256	3	P45973,Q13185	2
+Chromo domain subgroup [IPR017984]	0.6263537906137142	0.4004985570098414	0.6887893460869574	1.0	0.7872188061965256	3	P45973,Q13185	2
+Mu homology domain [IPR028565]	0.543202326599958	0.3598615797056834	0.7189506497749272	1.0	0.8133518945322393	4	Q9Y2T2	1
+Cyclic nucleotide-binding domain [IPR000595]	0.5418058835815835	0.3555534918177812	0.7221749785363603	1.0	0.8142784540598381	4	Q9Y4G8	1
+K Homology domain [IPR004087]	0.3123749590714897	0.3105001282466414	0.7561806619726945	1.0	0.8440581851000808	24	P51114,Q96AE4,Q07666,Q9Y2W6,P61978,P51116,Q06787,Q9Y6M1,Q96PU8	9
+Hotdog acyl-CoA thioesterase (ACOT)-type domain [IPR033120]	0.5687477444965633	0.3093768576789346	0.7570348723644322	1.0	0.8446077400088837	2	Q9Y305	1
+Saposin B type domain [IPR008139]	0.5535907614579485	0.2695941515034651	0.7874725002284104	1.0	0.8723117302008115	2	P07602	1
+CBS domain [IPR000644]	0.4341410440931986	0.2584987819529195	0.7960219888507334	1.0	0.8768462851695081	5	P51790	1
+Histone deacetylase domain [IPR023801]	0.5431252255503366	0.2438685648168976	0.8073326158871499	1.0	0.8860248739934962	2	Q92769	1
+F-box domain [IPR001810]	0.5380728978707954	0.2319744179486322	0.8165578833955096	1.0	0.8926505937740482	2	Q14241	1
+Nucleoporin, Nup133/Nup155-like, C-terminal [IPR007187]	0.5279682425117218	0.2092323646591677	0.8342668481829079	1.0	0.9060860044946054	2	Q8WUM0	1
+Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091]	0.3558208454718096	0.2070328656064484	0.8359841914643769	1.0	0.9075288850594676	9	O15254	1
+Ubiquitin-associated domain [IPR015940]	0.3626199138614929	0.2036565646338937	0.8386218871503726	1.0	0.9097739044918386	8	Q04323,Q14157	2
+Ribosomal protein S5, C-terminal [IPR005324]	0.5185853482497192	0.1893820698487529	0.8497933763719607	1.0	0.9161102562328176	2	P15880	1
+Ribosomal protein S5, N-terminal [IPR013810]	0.5185853482497192	0.1893820698487529	0.8497933763719607	1.0	0.9161102562328176	2	P15880	1
+Ribosome receptor lysine/proline rich [IPR007794]	0.5178635871526425	0.1879061401679058	0.8509502293217146	1.0	0.9165287656838405	2	Q86UP2	1
+Band 7 domain [IPR001107]	0.3710910445808401	0.1806527369992951	0.8566401586925119	1.0	0.9211428481632298	6	Q99623	1
+Ras GTPase-activating domain [IPR001936]	0.537545126353785	0.1784221291027905	0.8583914716174057	1.0	0.9211428481632298	3	P46940,P20936	2
+Damage-control phosphatase ARMT1-like, metal-binding domain [IPR002791]	0.5084806928906429	0.1693860643932749	0.8654929841249663	1.0	0.9270585704211434	2	Q9NVE7	1
+Proteasome component (PCI) domain [IPR000717]	0.3011429673168902	0.160026660162116	0.8728600730731848	1.0	0.9334844311931216	17	P48556,P61201,O00231,Q9Y262,P60228,Q9BT78	6
+Legume-like lectin [IPR005052]	0.5023457235654909	0.1579481514233127	0.8744976549008601	1.0	0.9337042664860968	2	Q12907	1
+Phospholipid/glycerol acyltransferase [IPR002123]	0.4663865045647024	0.1540698125781845	0.8775546901207592	1.0	0.9353977722075608	4	Q8NF37	1
+HR1 rho-binding domain [IPR011072]	0.5001804402742587	0.1540380741350816	0.8775797150125437	1.0	0.9353977722075608	2	O75116	1
+Staufen, C-terminal [IPR032478]	0.4951281125947204	0.1451715780625323	0.8845754056066097	1.0	0.9385974857634856	2	O95793	1
+Proteasomal ATPase OB C-terminal domain [IPR032501]	0.3898121387283267	0.1306735579430245	0.8960335506567993	1.0	0.9484201971304996	5	P43686,P62191,P62195,P17980	4
+UBX domain [IPR001012]	0.3794695472118546	0.1051910082652973	0.916224245503222	1.0	0.9645770811928372	5	Q04323,Q9UNZ2	2
+GYF domain [IPR003169]	0.467701190905803	0.1032428993212767	0.9177701930696556	1.0	0.9657689948713148	2	O95400	1
+DnaJ domain [IPR001623]	0.2926054545410154	0.0985341760077548	0.9215081354598866	1.0	0.968828823497016	15	Q96EY1,Q9NVH1,Q96KC8,Q9UGP8,Q8IXB1,O75190	6
+PABP, RNA recognition motif 2 [IPR045305]	0.4568747744496466	0.0894975312215263	0.9286865155116604	1.0	0.9741817200917822	2	P11940	1
+Guanylate kinase-like domain [IPR008144]	0.4332319769359933	0.0879352914893548	0.9299281066870684	1.0	0.974608083074817	4	Q9NZW5,Q14168	2
+Guanylate kinase/L-type calcium channel beta subunit [IPR008145]	0.4332319769359933	0.0879352914893548	0.9299281066870684	1.0	0.974608083074817	4	Q9NZW5,Q14168	2
+PTBP1, RNA recognition motif 2-like [IPR021790]	0.4812274368230986	0.0833942364470059	0.93353807119894	1.0	0.977952360044132	3	Q8WVV9,P14866	2
+26S proteasome regulatory subunit Rpn7, N-terminal [IPR045135]	0.4511006856730301	0.0827886707809334	0.93401957760898	1.0	0.9780178080481648	2	Q15008	1
+Heat shock chaperonin-binding [IPR006636]	0.4449657163478765	0.0761205166680066	0.9393232175549016	1.0	0.9804977051219228	2	P54727	1
+HECT domain [IPR000569]	0.3258643466071148	0.0704451981061526	0.9438393176923064	1.0	0.9825695662327578	8	P46934	1
+COMM domain [IPR017920]	0.4287260916636518	0.0606561283796613	0.9516330717902446	1.0	0.9867221632867308	2	Q9Y6G5	1
+Serine hydroxymethyltransferase-like domain [IPR039429]	0.4243955250811871	0.057042351375192	0.9545114585248466	1.0	0.9892672043503516	2	P34896	1
+TGS [IPR004095]	0.3287045316086462	0.0564601328571184	0.9549752542090156	1.0	0.9893085855853716	6	Q9NYK5,Q9NTK5	2
+Spen paralogue/orthologue C-terminal, metazoa [IPR010912]	0.4207867195958057	0.0541867502436129	0.9567863769493958	1.0	0.9903154786934588	2	Q96T37	1
+SAM-dependent methyltransferase RsmB/NOP2-type [IPR001678]	0.4113656452855257	0.0524982745719774	0.9581316701328436	1.0	0.990380566027483	4	Q08J23	1
+U2A'/phosphoprotein 32 family A, C-terminal [IPR003603]	0.4505415162454806	0.0472399153519119	0.9623220151667836	1.0	0.9928380813140206	3	P39687,Q92688	2
+DNA-directed DNA polymerase, family B, multifunctional domain [IPR006134]	0.4472924187725562	0.0440190898414135	0.9648891871225084	1.0	0.9928380813140206	3	P09884,Q07864	2
+DNA-directed DNA polymerase, family B, exonuclease domain [IPR006133]	0.4472924187725562	0.0440190898414135	0.9648891871225084	1.0	0.9928380813140206	3	P09884,Q07864	2
+Arfaptin homology (AH) domain [IPR010504]	0.4027426921688875	0.041904691770419	0.9665746761932348	1.0	0.9938261208083744	2	P53365	1
+Sterile alpha motif domain [IPR001660]	0.4028043950698923	0.040384280938337	0.9677867620201464	1.0	0.9943239593496273	4	Q9P246	1
+Zinc finger, ZZ-type [IPR000433]	0.3998556477805799	0.0402285732846169	0.967910897875901	1.0	0.9943239593496273	2	P46939	1
+Syntaxin, N-terminal domain [IPR006011]	0.4364620938628087	0.034075866292409	0.9728166532147032	1.0	0.9967010362547956	3	Q86Y82,Q12846	2
+Elongation factor 1 beta central acidic region, eukaryote [IPR018940]	0.3857813063875767	0.0330843413237392	0.9736073297281318	1.0	0.9967010362547956	2	P29692	1
+Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain [IPR014038]	0.3857813063875767	0.0330843413237392	0.9736073297281318	1.0	0.9967010362547956	2	P29692	1
+DNA ligase, ATP-dependent, N-terminal [IPR012308]	0.3832551425478112	0.031970989286889	0.9744951862611156	1.0	0.9967010362547956	2	P18858	1
+DNA ligase, ATP-dependent, central [IPR012310]	0.3832551425478112	0.031970989286889	0.9744951862611156	1.0	0.9967010362547956	2	P18858	1
+DNA ligase, ATP-dependent, C-terminal [IPR012309]	0.3832551425478112	0.031970989286889	0.9744951862611156	1.0	0.9967010362547956	2	P18858	1
+Target SNARE coiled-coil homology domain [IPR000727]	0.3025772636466568	0.0307938935733468	0.9754339103347552	1.0	0.9969234038211922	10	Q86Y82,P56962,Q13190,O60499	4
+RNA polymerase, beta subunit, protrusion [IPR007644]	0.3655719956694249	0.0254459616748466	0.9796992508474088	1.0	0.998523166584215	2	P30876	1
+DNA-directed RNA polymerase, subunit 2, hybrid-binding domain [IPR007120]	0.3655719956694249	0.0254459616748466	0.9796992508474088	1.0	0.998523166584215	2	P30876	1
+RNA polymerase Rpb2, domain 3 [IPR007645]	0.3655719956694249	0.0254459616748466	0.9796992508474088	1.0	0.998523166584215	2	P30876	1
+RNA polymerase Rpb2, domain 2 [IPR007642]	0.3655719956694249	0.0254459616748466	0.9796992508474088	1.0	0.998523166584215	2	P30876	1
+RNA polymerase Rpb2, domain 7 [IPR007641]	0.3655719956694249	0.0254459616748466	0.9796992508474088	1.0	0.998523166584215	2	P30876	1
+Alanyl-tRNA synthetase, class IIc, N-terminal [IPR018164]	0.3446409238541981	0.0201400156124578	0.9839316787685232	1.0	1.0	2	Q5JTZ9	1
+ENTH  domain [IPR013809]	0.3186575243594298	0.0162142115299012	0.987063497793002	1.0	1.0	2	Q14677	1
+Methyltransferase type 11 [IPR013216]	0.3175748827138144	0.0160989642450374	0.9871554398213762	1.0	1.0	2	Q8N6R0	1
+Beta-adaptin appendage, C-terminal subdomain [IPR015151]	0.4021660649819419	0.009973929387198	0.9920420876728502	1.0	1.0	3	P63010,Q10567	2
+Proteasome activator PA28, C-terminal domain [IPR003186]	0.3942238267147956	0.0058169070267138	0.99535880586533	1.0	1.0	3	P61289,Q9UL46	2
+Proteasome activator PA28, N-terminal domain [IPR003185]	0.3942238267147956	0.0058169070267138	0.99535880586533	1.0	1.0	3	P61289,Q9UL46	2
+Longin domain [IPR010908]	0.3855595667869967	0.0018143931434746	0.9985523245178918	1.0	1.0	3	P51809,O75396	2
+v-SNARE, coiled-coil homology domain [IPR042855]	0.3855595667869967	0.0018143931434746	0.9985523245178918	1.0	1.0	3	P51809,O75396	2

interpro_family/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Proteasome, subunit alpha/beta [IPR001353]", "1": "Proteasome B-type subunit [IPR023333]", "2": "Mitochondrial carrier protein [IPR002067]"}