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interpro_active_site/advanced/idx2term.json

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+{}

interpro_active_site/basic/idx2term.json

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+{}

interpro_active_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:958520592fc4097db335ff7f2e36a9aa106664ecde34419c333b267f352bcd78
+size 62286

interpro_active_site/df_merge.tsv

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+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_active_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2771,
+    "annotations_size": 56,
+    "title": "Average number of proteins per term",
+    "value": 2.392857142857143
+}

interpro_active_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C323/C323_val_log2fc"}

interpro_active_site/result.tsv

@@ -0,0 +1,4 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]	0.6388667468526452	0.9433680502454516	0.3454926794281667	0.9999999999508852	0.6449196682659113	4	P06576	1
+Glycosyl hydrolases family 31, active site [IPR030458]	0.6735283495846875	0.2849225963306114	0.7757034438260719	1.0	0.9520192735205868	2	Q14697	1
+Thiolase, acyl-enzyme intermediate active site [IPR020615]	0.3872017353579023	0.2481851916377706	0.803991123350922	1.0	0.9520192735205868	5	P09110,P55084,P24752,P42765	4

interpro_active_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase,  active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT1", "AKT2", "APEH", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "BLMH", "CAPN1", "CASP2", "CASP3", "CASP6", "CDK1", "CDK13", "CDK2", "CDK4", "CDK6", "CHEK2", "CHUK", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSB", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLUD1", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "IGF1R", "LDHA", "LDHB", "LONP1", "MAP2K1", "MAP2K2", "MAP3K7", "MAPK1", "MAPK3", "MARK2", "MDH1", "MDH2", "MTMR6", "NEK9", "NME1", "NME2", "PAK2", "PASK", "PBK", "PGAM1", "PKM", "PKMYT1", "PKN2", "PLK1", "PREP", "PRKAA1", "PRKACA", "PRPF4B", "PTK7", "PTPN1", "PTPN11", "RNASET2", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SUCLG1", "TALDO1", "TOP1", "TPI1", "TPP2", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UMPS", "UNG", "VRK1"], "leading_proteins": ["ACAA1", "ACAA2", "ACAT1", "ATP5B", "GANAB", "HADHB"]}

interpro_binding_site/advanced/idx2term.json

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+{}

interpro_binding_site/basic/idx2term.json

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+{"0": "EF-Hand 1, calcium-binding site [IPR018247]"}

interpro_binding_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:ea2c0b5ace721c24f30d402f14bc0f18fc54ae03e3ccfb3727d81665ec76bca8
+size 61951

interpro_binding_site/df_merge.tsv

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+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_binding_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2771,
+    "annotations_size": 28,
+    "title": "Average number of proteins per term",
+    "value": 4.285714285714286
+}

interpro_binding_site/paths.json

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+{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C323/C323_val_log2fc"}

interpro_binding_site/result.tsv

@@ -0,0 +1,6 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+EF-Hand 1, calcium-binding site [IPR018247]	0.5248133862612591	1.7901685366943998	0.0734268214882858	0.8817959690130057	0.5356067818957921	31	O95302,P80303,Q96AY3,O43852,Q9NWM8,Q14257	6
+Peptidase M16, zinc-binding site [IPR001431]	0.6161655708151981	1.0893854740302382	0.2759839343610588	0.9998817095489752	0.650463084973705	5	O43847,P22695,O75439	3
+Beta tubulin, autoregulation binding site [IPR013838]	0.448892220583825	0.525969041805756	0.5989097169430933	0.9999999999922236	0.931637337467034	6	Q13885,P07437	2
+Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]	0.6287468400144476	0.1954925150557745	0.8450073967611234	1.0	0.954473352010772	2	P34897	1
+2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]	0.5803539183820892	0.1218558285974503	0.9030131985193206	1.0	0.954473352010772	2	P10515	1

interpro_binding_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]"], "available_proteins": ["ACACA", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT1", "AKT2", "APEX1", "ASPM", "BPNT1", "CALU", "CAPN1", "CDK1", "CDK13", "CDK2", "CDK4", "CDK6", "CHUK", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DLAT", "DLST", "DST", "EHD1", "EIF2AK2", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "GCAT", "GOT1", "GOT2", "GPD2", "HK1", "HK2", "IDE", "IGF1R", "ILKAP", "IQGAP1", "LETM1", "MACF1", "MAP2K1", "MAP2K2", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MARK2", "MCCC1", "MICU1", "MYH10", "MYH9", "MYO1B", "MYO1C", "MYO1D", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXSR1", "PA2G4", "PAK2", "PASK", "PC", "PCCA", "PDCD6", "PEF1", "PGD", "PKMYT1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1F", "PPM1G", "PRKAA1", "PRKACA", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "RHOT1", "RHOT2", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "STK4", "TKT", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "UQCRC2", "VRK1"], "leading_proteins": ["CALU", "DLAT", "FKBP10", "FKBP14", "FKBP9", "NRDC", "NUCB2", "PMPCB", "RCN2", "SHMT2", "TUBB", "TUBB2A", "UQCRC2"]}

interpro_conserved_site/advanced/idx2term.json

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+{}

interpro_conserved_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Thioredoxin, conserved site [IPR017937]", "1": "Intermediate filament protein, conserved site [IPR018039]", "2": "Kinesin motor domain, conserved site [IPR019821]"}

interpro_conserved_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:2d954d5f7eb8f9c90b7147d580b9fc27cde1ee881ef7d4b2fcb5644267dcd388
+size 69730

interpro_conserved_site/df_merge.tsv

@@ -0,0 +1,2 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Acyl-CoA dehydrogenase, conserved site [IPR006089]	1	6	2.4771585507442104	0.0132433056940843	2.924757281553398	6.072815533980583	-0.8305136503397285	0.3058599896865968	1.8252992012537188	0.6679477589532989	1.090766824396359	0.268185473646236	0.0023522483882682	0.000647621121882	0.0025156479029566	0.0146338936924203	0.0536294240020009

interpro_conserved_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2771,
+    "annotations_size": 257,
+    "title": "Average number of proteins per term",
+    "value": 2.5525291828793772
+}

interpro_conserved_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C323/C323_val_log2fc"}

interpro_conserved_site/result.tsv

@@ -0,0 +1,25 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Acyl-CoA dehydrogenase, conserved site [IPR006089]	0.9050694964996676	2.4771585507442104	0.0132433056940843	0.9674919500087348	0.5325348229702722	6	P11310	1
+Thioredoxin, conserved site [IPR017937]	0.6977102464738515	1.7090278608489653	0.0874457888073925	0.9999999999388384	0.5325348229702722	11	Q8IXB1,O95881,P13667,Q9H3N1,P07237,P30101,Q15084	7
+Intermediate filament protein, conserved site [IPR018039]	0.6960181989684736	1.630846317106199	0.1029227514852126	0.9999999999992462	0.5398193292183604	8	P07196,P08670,P02545,P07197,Q16352	5
+Annexin repeat, conserved site [IPR018252]	0.6993021153859269	1.6090226624320465	0.1076113863212526	0.999999999999804	0.5415478736933816	6	P08133,P04083,P07355,P09525	4
+Ubiquitin interacting motif [IPR003903]	0.8470670564491729	1.594543855330366	0.1108142762987214	0.9999999999999222	0.5415478736933816	3	Q92783	1
+Calreticulin/calnexin, conserved site [IPR018124]	0.8421242774566391	1.575537610454928	0.1151324041922134	0.9999999999999776	0.5415478736933816	3	P27797,O14967	2
+Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]	0.7206887235324906	1.5266951977501546	0.1268368221183569	0.9999999999999992	0.5415478736933816	5	P48735	1
+Aldehyde dehydrogenase, cysteine active site [IPR016160]	0.5839519387288143	1.1211855387402596	0.2622088940050031	1.0	0.7457589897043286	8	O94788	1
+HMG box A DNA-binding domain, conserved site [IPR017967]	0.711343930635842	1.0705428695430403	0.2843750233113782	1.0	0.7457589897043286	3	O15347,P09429	2
+Chromo domain, conserved site [IPR023779]	0.6249217595209685	0.890930460998771	0.3729664774548222	1.0	0.8638070383361729	4	P45973,Q13185	2
+Aldehyde dehydrogenase, glutamic acid active site [IPR029510]	0.5046064916580547	0.7657510141189035	0.4438244665442148	1.0	0.8875725857341321	8	O94788	1
+Syntaxin/epimorphin, conserved site [IPR006012]	0.4989843704028441	0.7342751878528382	0.462781036919742	1.0	0.8875725857341321	7	Q86Y82,Q9P2W9	2
+ABC transporter-like, conserved site [IPR017871]	0.4672676479193894	0.6210790070756117	0.5345476409948478	1.0	0.9409502995594238	10	P33527	1
+Hexapeptide transferase, conserved site [IPR018357]	0.7916215240158894	0.6040022726906167	0.5458421311825901	1.0	0.9435060544387734	2	Q96IJ6	1
+Tubulin, conserved site [IPR017975]	0.448892220583825	0.525969041805756	0.5989097169430933	1.0	0.9560235854309004	6	Q13885,P07437	2
+Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]	0.5465155289821346	0.4779162658702675	0.632709803712064	1.0	0.99338751384657	3	O60568	1
+Heat shock protein Hsp90, conserved site [IPR019805]	0.4890411013914615	0.3102521563914859	0.756369210841195	1.0	1.0	3	P14625	1
+Glycosyl hydrolases family 31, conserved site [IPR030459]	0.6735283495846875	0.2849225963306114	0.7757034438260719	1.0	1.0	2	Q14697	1
+Kinesin motor domain, conserved site [IPR019821]	0.358630562490301	0.2215510704849614	0.8246633759139981	1.0	1.0	10	Q14807,Q12756,O95235,Q02241,O00139,Q9Y496,P33176,Q99661	8
+Zinc finger, RING-type, conserved site [IPR017907]	0.3577780157499307	0.2189274216000299	0.8267065852278259	1.0	1.0	9	Q14527,O75150	2
+Proteasome beta-type subunit, conserved site [IPR016050]	0.2987014735694143	0.0888017071081636	0.929239500976928	1.0	1.0	8	P28074,P49721,P28070,Q99436	4
+Guanylate kinase, conserved site [IPR020590]	0.3705145272429761	0.0849574690337697	0.932295203204852	1.0	1.0	3	Q14168	1
+Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]	0.2460260115607005	0.0177291126551816	0.9858549557546796	1.0	1.0	3	Q9P2R7,Q96I99	2
+Vinculin, conserved site [IPR000633]	0.3755868544600915	0.0176315398828231	0.9859327953962176	1.0	1.0	2	P35221	1

interpro_conserved_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Bromodomain, conserved site [IPR018359]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific,  conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Heavy-metal-associated, conserved site [IPR017969]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Pyridoxamine 5'-phosphate oxidase, conserved site [IPR019740]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P,  conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class II, conserved site [IPR002011]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB10", "ABCB7", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP3M1", "APEX1", "ARHGEF7", "ATAD1", "ATP5C1", "ATP5O", "ATP7B", "BAG6", "BAK1", "BAX", "BAZ1A", "BAZ1B", "BCAT2", "BCS1L", "BOP1", "BPNT1", "BRD2", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZB", "CASK", "CBR1", "CBX1", "CBX3", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD81", "CDKAL1", "CHAF1B", "CHD1", "CHD1L", "CHD4", "CLGN", "CMPK1", "CNDP2", "COPA", "COPZ1", "CORO1C", "CPOX", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX40", "DHX8", "DHX9", "DIDO1", "DIS3", "DIS3L2", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC9", "DNM1", "DNM1L", "DNM2", "DNMT1", "DRG1", "DRG2", "DSG2", "DST", "DTL", "DTYMK", "DYNLL1", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A3", "EIF4E", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPRS", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXC1", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLO1", "GMPPA", "GMPPB", "GNPDA1", "GNS", "GPI", "GRHPR", "GRWD1", "GSPT1", "GTF3C2", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IGF1R", "ILVBL", "IMPAD1", "IMPDH2", "INA", "IQGAP1", "IVD", "KDSR", "KIF11", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "LAMP1", "LARS", "LARS2", "LBR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MAPK3", "MARS", "MAT2A", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGST2", "MID1", "MIF", "MPI", "MPP2", "MPP6", "MPST", "MRPL3", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "MVK", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFV1", "NEFL", "NEFM", "NES", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD2", "NSF", "NSUN6", "NUBP2", "NUBPL", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF2", "PHF3", "PHGDH", "PHIP", "PIK3C2A", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PNP", "PNPLA6", "PNPO", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2E", "PPIB", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RASA1", "RCL1", "RDH13", "RDX", "RIDA", "RNF114", "RNF14", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RTN4IP1", "S100A10", "S100A11", "SART1", "SBDS", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC27A4", "SMARCA4", "SMS", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STRN", "STX10", "STX12", "STX17", "STX18", "STX4", "STX5", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE2", "TBL3", "TCP1", "TK1", "TLN1", "TMX1", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM21", "TRIM25", "TRIM27", "TRIM28", "TRIP13", "TRMT11", "TSFM", "TSPAN3", "TSPAN6", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UHRF1", "USP10", "USP11", "USP14", "USP19", "USP28", "USP33", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "WARS", "WDHD1", "WDR1", "WDR18", "WDR3", "WDR36", "WDR41", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2"], "leading_proteins": ["ABCC1", "ACADM", "ALDH1A2", "ANXA1", "ANXA2", "ANXA4", "ANXA6", "CALR", "CBX3", "CBX5", "CLGN", "CTNNA1", "DNAJC10", "GANAB", "GMPPA", "HLTF", "HMGB1", "HMGB3", "HSP90B1", "IDH2", "INA", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF5B", "LMNA", "MPP2", "NEFL", "NEFM", "P4HB", "PDIA3", "PDIA4", "PDIA6", "PLOD3", "PSMB2", "PSMB4", "PSMB5", "PSMB7", "RNF40", "STAM", "STX12", "STX18", "SUCLA2", "SUCLG2", "TMX1", "TUBB", "TUBB2A", "TXNDC12", "VIM"]}

interpro_domain/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "EF-hand domain [IPR002048]"}

interpro_domain/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "EF-hand domain [IPR002048]", "1": "Intermediate filament, rod domain [IPR039008]", "2": "G-patch domain [IPR000467]", "3": "RNA recognition motif domain [IPR000504]", "4": "High mobility group box domain [IPR009071]", "5": "Thioredoxin domain [IPR013766]", "6": "Linker histone H1/H5, domain H15 [IPR005818]", "7": "Importin-beta, N-terminal domain [IPR001494]", "8": "Kinesin motor domain [IPR001752]", "9": "PDZ domain [IPR001478]", "10": "GTP binding domain [IPR006073]", "11": "RNA helicase, DEAD-box type, Q motif [IPR014014]", "12": "AAA+ ATPase domain [IPR003593]"}

interpro_domain/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:00b44f511f5a78cebed5e7fb9ece8822670033e666a81fe2df1345168d86156b
+size 141124

interpro_domain/df_merge.tsv

@@ -0,0 +1,8 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Acyl-CoA dehydrogenase/oxidase C-terminal [IPR009075]	1	7	2.337533496863303	0.0194114613152049	3.0242718446601944	6.859223300970874	-0.7822498405130026	0.333446735324871	1.9104701815129164	0.8838284872060136	1.0683154875068148	0.2771664207853273	0.0029397335579464	0.0010343090391069	0.0039921150854813	0.0227865880642579	0.0103919051808895
+Acyl-CoA dehydrogenase/oxidase, N-terminal [IPR013786]	1	7	2.337533496863303	0.0194114613152049	3.0242718446601944	6.859223300970874	-0.7822498405130026	0.333446735324871	1.9104701815129164	0.8838284872060136	1.0683154875068148	0.2771664207853273	0.0029397335579464	0.0010343090391069	0.0039921150854813	0.0227865880642579	0.0103919051808895
+Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091]	2	9	2.257483635660726	0.0239778708929652	3.058252427184466	8.66747572815534	-0.2891462610619146	0.4487119500832195	1.9337334618113893	1.0854780329838505	1.0649766578353217	0.2871756386364707	0.0035269880473108	0.0015075035399645	0.0001833288791406	0.0025675639060761	0.0019443402252438
+SET domain [IPR001214]	1	7	2.180988975576108	0.0291842319065991	2.3762135922330097	7.203883495145631	0.2385276779443848	0.4071855892228946	1.7492625999828462	2.5849047354362957	1.1957336270516616	0.3024983972109138	0.0117243548291303	0.1788224008957527	0.0573531962335191	0.2497167706923579	0.1254299298894934
+EF-hand domain [IPR002048]	7	38	2.080650311458129	0.0374659252304765	12.385922330097088	43.512135922330096	1.0171858714399242	0.3947118087831401	4.608360476919044	4.087317384177653	1.201458704248258	0.3652478399429377	1.0	0.0014196759684226	0.0028349238604578	0.002753033778234	0.0030592480784856
+K Homology domain [IPR004087]	3	24	2.043214147860997	0.0410312438226305	8.029126213592233	22.796116504854368	0.328818420881894	0.600646587147133	4.351556602822176	1.3994397166034702	0.8923876485619237	0.3352669927506027	1.0	0.0112943240362007	0.0039222152641545	0.0076999170588955	0.0198874102408346
+K Homology domain, type 1 [IPR004088]	3	24	2.027683654955431	0.0425925448949182	8.5	23.218446601941743	0.4539576731478794	0.576935027430011	4.690674491420825	1.6401661988255969	0.9187340965418598	0.3398774289684012	1.0	0.0119629297909749	0.0042717712834537	0.0085651992096032	0.0224202020359025

interpro_domain/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2771,
+    "annotations_size": 2334,
+    "title": "Average number of proteins per term",
+    "value": 2.0972579263067694
+}

interpro_domain/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C323/C323_val_log2fc"}

interpro_domain/result.tsv

@@ -0,0 +1,180 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Acyl-CoA dehydrogenase/oxidase C-terminal [IPR009075]	0.8645166667752721	2.337533496863303	0.0194114613152049	1.0	0.5502911836650896	7	P11310	1
+Acyl-CoA dehydrogenase/oxidase, N-terminal [IPR013786]	0.8645166667752721	2.337533496863303	0.0194114613152049	1.0	0.5502911836650896	7	P11310	1
+Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091]	0.8323491123880514	2.257483635660726	0.0239778708929652	1.0	0.5502911836650896	9	P11310,P49748	2
+SET domain [IPR001214]	0.8271353621772396	2.1809889755761076	0.0291842319065991	1.0	0.5502911836650896	7	Q9H7B4	1
+EF-hand domain [IPR002048]	0.4960554686677302	2.080650311458129	0.0374659252304765	1.0	0.5502911836650896	38	O95302,P80303,Q96AY3,O43852,P35609,Q9NWM8,Q14257	7
+K Homology domain [IPR004087]	0.6501523322551682	2.0432141478609975	0.0410312438226305	1.0	0.5502911836650896	24	Q96PU8,Q9Y6M1,Q9Y2W6	3
+K Homology domain, type 1 [IPR004088]	0.6474876468072095	2.027683654955431	0.0425925448949182	1.0	0.5502911836650896	24	Q96PU8,Q9Y6M1,Q9Y2W6	3
+Intermediate filament head, DNA-binding domain [IPR006821]	0.9161546801590152	1.995849012820376	0.0459503599840256	1.0	0.5502911836650896	4	P07196,P08670,Q16352	3
+Disulphide isomerase [IPR005788]	0.8156182212581353	1.9163110381847064	0.0553255167025752	1.0	0.5502911836650896	5	P30101,Q15084,P07237,P13667	4
+FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]	0.7146614074083044	1.7880547604824206	0.0737671733984994	1.0	0.5502911836650896	11	Q9NWM8,O95302	2
+FAD/NAD(P)-binding domain [IPR023753]	0.7721087616262117	1.739190507361695	0.0820012586384548	1.0	0.5560895925292341	5	O95831	1
+Zinc finger, RanBP2-type [IPR001876]	0.7110516227723825	1.6983586936443231	0.0894400831837676	1.0	0.5560895925292341	8	Q92804,P98175	2
+ERAP1-like C-terminal domain [IPR024571]	0.8306284464902436	1.67638050638794	0.0936636847421912	1.0	0.5560895925292341	4	Q9NZ08	1
+Intermediate filament, rod domain [IPR039008]	0.6960181989684736	1.630846317106199	0.1029227514852126	1.0	0.5647970394930221	8	P07196,P08670,P02545,P07197,Q16352	5
+Aminopeptidase N-like , N-terminal domain [IPR045357]	0.6894041080985267	1.565519477866565	0.1174611539431977	1.0	0.5824574612177154	6	Q9NZ08	1
+Peptidase M1, membrane alanine aminopeptidase [IPR014782]	0.6894041080985267	1.565519477866565	0.1174611539431977	1.0	0.5824574612177154	6	Q9NZ08	1
+Isopropylmalate dehydrogenase-like domain [IPR024084]	0.7206887235324906	1.5266951977501546	0.1268368221183569	1.0	0.586870456260127	5	P48735	1
+Chromo domain subgroup [IPR017984]	0.821531791907514	1.4961856384800176	0.1346052859921638	1.0	0.5883432501605337	3	P45973,Q13185	2
+Chromo shadow domain [IPR008251]	0.821531791907514	1.4961856384800176	0.1346052859921638	1.0	0.5883432501605337	3	P45973,Q13185	2
+LIS1 homology motif [IPR006594]	0.6629900595164537	1.448898405217314	0.1473659565976353	1.0	0.5941499766885676	6	Q13428,O95684,Q14978	3
+NOPS [IPR012975]	0.7934040396702712	1.3874680915433386	0.1652990744109579	1.0	0.6139866518719066	3	Q15233	1
+Major sperm protein (MSP) domain [IPR000535]	0.7799855491329445	1.3355304497187035	0.1817027961942656	1.0	0.6259020104828993	3	O95292,Q8NHP6	2
+EF-hand, Ca insensitive [IPR014837]	0.7278641127574818	1.2836104783884916	0.1992782815538019	1.0	0.6550122664821056	4	P35609,Q13813,O43707	3
+RNA recognition motif domain, eukaryote [IPR003954]	0.6030737291417899	1.2828786750087653	0.199534585033752	1.0	0.6550122664821056	12	Q14011,P38159,Q96E39,P19338	4
+Immunoglobulin-like domain [IPR007110]	0.6026501507692256	1.2590995597871262	0.2079943734325369	1.0	0.6594538007694193	11	Q08722,P01889,Q9Y639,P78310	4
+Dbl homology (DH) domain [IPR000219]	0.756875972146754	1.2460855781036173	0.2127329788859286	1.0	0.6641856015770239	3	Q92974	1
+Immunoglobulin V-set domain [IPR013106]	0.7502332472747326	1.2203965447876408	0.2223145865533871	1.0	0.6731277708981568	3	P78310	1
+Cyclic nucleotide-binding domain [IPR000595]	0.704419151502447	1.1935010846919056	0.2326731876049192	1.0	0.680525338182809	4	Q8IY17,Q9Y4G8	2
+G-patch domain [IPR000467]	0.5794844865490958	1.1687828127363094	0.2424911467946389	1.0	0.691055356066773	12	P98175,Q8IWX8,Q92917,Q9UBB9,Q5T3I0	5
+RBM3/CIRBP, RNA recognition motif [IPR034278]	0.9559407728421816	1.16352003895457	0.2446185726098448	1.0	0.6946073571685498	2	P98179	1
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	0.576139941384191	1.073584025350447	0.2830091604931835	1.0	0.7413505955006624	7	Q9UMX5	1
+Prolyl 4-hydroxylase, alpha subunit [IPR006620]	0.6117452298271451	1.0709382278517068	0.2841972056855124	1.0	0.742795384176916	5	P13674,Q32P28	2
+Oxoglutarate/iron-dependent dioxygenase [IPR005123]	0.6117452298271451	1.0709382278517068	0.2841972056855124	1.0	0.742795384176916	5	P13674,Q32P28	2
+Transcription factor IIS, N-terminal [IPR017923]	0.7102669184104295	1.066412528238133	0.2862372007994254	1.0	0.7431341787161945	3	Q14241	1
+Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type [IPR003617]	0.7102669184104295	1.066412528238133	0.2862372007994254	1.0	0.7431341787161945	3	Q14241	1
+Immunoglobulin subtype [IPR003599]	0.568436073585706	1.0390767439216615	0.2987690458409227	1.0	0.7555641436228747	7	Q9Y639,P78310	2
+Immunoglobulin subtype 2 [IPR003598]	0.568436073585706	1.0390767439216615	0.2987690458409227	1.0	0.7555641436228747	7	Q9Y639,P78310	2
+Spen paralogue and orthologue SPOC, C-terminal [IPR012921]	0.6585723722502351	1.018060009518279	0.308649438538163	1.0	0.7625305709939977	4	Q92576,Q96T58	2
+VHS domain [IPR002014]	0.9147706753340564	1.0168658524641458	0.3092172497914269	1.0	0.7625305709939977	2	Q92783	1
+SWIRM domain [IPR007526]	0.6557911117346067	1.0074826802826498	0.3137028766608716	1.0	0.7673160659763499	4	Q8NB78	1
+ABC transporter type 1, transmembrane domain [IPR011527]	0.5633622522249571	1.0068152313521876	0.3140235737457209	1.0	0.7673160659763499	6	P33527	1
+Lamin tail domain [IPR001322]	0.6907514450866988	0.9918444672528504	0.3212734021492389	1.0	0.7673160659763499	3	P20700,P02545	2
+ERM family, FERM domain C-lobe [IPR041789]	0.6859737223784561	0.9736803897956872	0.3302152571261505	1.0	0.7769379134399549	3	P35241	1
+Extended PHD (ePHD) domain [IPR034732]	0.9017695919104296	0.9711465274620906	0.3314753172261728	1.0	0.7791172108820619	2	Q03164	1
+RBM1CTR [IPR012604]	0.8981581798483157	0.958508925738537	0.3378061928139977	1.0	0.7833433683235779	2	Q96E39	1
+ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain [IPR004100]	0.6388667468526452	0.9433680502454516	0.3454926794281667	1.0	0.7859453350734319	4	P06576	1
+ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain [IPR000194]	0.6388667468526452	0.9433680502454516	0.3454926794281667	1.0	0.7859453350734319	4	P06576	1
+Immunoglobulin C1-set [IPR003597]	0.6353512338806001	0.9301117102376236	0.3523132482802222	1.0	0.7952602722302116	4	P01889,Q5ZPR3	2
+Zinc finger, PHD-type [IPR001965]	0.5233838698496724	0.9173599109211584	0.3589540726904201	1.0	0.8040295639725917	13	Q92576,Q03164	2
+LEM-like domain [IPR013146]	0.8829902491874342	0.9057603470637652	0.3650627133110515	1.0	0.8111219366147268	2	P42166	1
+Septin-type guanine nucleotide-binding (G) domain [IPR030379]	0.5710427155870299	0.9024051339184872	0.3668416949006634	1.0	0.8131135003781087	5	Q14141	1
+RNA recognition motif domain [IPR000504]	0.5121065170324665	0.8774118513481483	0.3802629783048403	1.0	0.8252000203044167	108	Q9NWH9,Q16630,Q96E39,Q13595,Q14103,Q13247,Q76FK4,P52272,P35637,P07910,P26599,Q9UKM9,P38159,P98175,P33240,Q9NTZ6,P43243,P09651,Q92804,Q96EP5,O14979,Q8WXF1,Q96T37,Q9BWF3,Q8N684,Q13151,P26368,Q92879,P51991,Q9NW13,Q96I25,P22626,O43390,Q15427,P08621,P84103,Q01844,Q96T58,Q13243,P09012,Q9Y6M1,Q14498,Q9Y5S9,P31942,P31943,Q16629,Q15233,Q8WVV9,Q15056,P98179,P42696,Q13242,P23588,Q15717,P62995,P23246,Q07955,Q99729,P19338,Q13283,Q01085,Q14011,Q96PK6	63
+Zinc finger, CCCH-type [IPR000571]	0.5196524519467901	0.8668614670580242	0.3860179184741841	1.0	0.8310922098498147	11	P42694,Q96QC0,Q86VM9	3
+SANT/Myb domain [IPR001005]	0.5241892075633657	0.862157314702457	0.3886009552962393	1.0	0.8351700088963375	9	P28370,Q8TAQ2	2
+CARG-binding factor, N-terminal [IPR012956]	0.8609606356085123	0.8302318871705879	0.4064076898261231	1.0	0.8518131207243195	2	Q99729	1
+Sterile alpha motif domain [IPR001660]	0.6026286883596615	0.8080561077474212	0.4190582834130456	1.0	0.8632674611527348	4	Q9Y6Y8,Q9P246	2
+CCAAT-binding factor [IPR005612]	0.6282514450867089	0.7585220015024151	0.4481385468618295	1.0	0.8783503119214954	3	Q8WTT2,Q9BVI4	2
+Aldehyde dehydrogenase domain [IPR015590]	0.4961439280305066	0.7473570131744621	0.4548480861418364	1.0	0.8891251533124342	10	O94788	1
+High mobility group box domain [IPR009071]	0.4916814167150791	0.7387318394390429	0.4600698479455916	1.0	0.8940907786053378	11	P09429,O94842,Q969G3,O15347,Q00059	5
+SWAP/Surp [IPR000061]	0.5003625466096296	0.7344211846417793	0.4626920793380837	1.0	0.8947169123240161	6	Q15459,Q8IWX8,Q8IWZ8,Q12872	4
+Histone H2A, C-terminal domain [IPR032454]	0.6156069364161917	0.7128321293259224	0.475949641446193	1.0	0.8985017138865302	3	Q9P0M6,O75367	2
+Histone H2A/H2B/H3 [IPR007125]	0.6156069364161917	0.7128321293259224	0.475949641446193	1.0	0.8985017138865302	3	Q9P0M6,O75367	2
+LEM domain [IPR003887]	0.5203378828886273	0.6986308359287521	0.4847827677911804	1.0	0.9044718009011076	5	Q86XL3,P42167,P42166	3
+Zinc finger, PHD-finger [IPR019787]	0.4764503988442493	0.6822882497685082	0.4950567015315279	1.0	0.906749109396244	12	Q03164	1
+SANT domain [IPR017884]	0.4819834293862299	0.6625983633266186	0.5075878186826703	1.0	0.914833952745446	7	P28370	1
+ABC transporter-like, ATP-binding domain [IPR003439]	0.4672676479193894	0.6210790070756117	0.5345476409948478	1.0	0.92485855751073	10	P33527	1
+PTBP1, RNA recognition motif 2-like [IPR021790]	0.5855976450330236	0.6073358076273195	0.5436280795729715	1.0	0.9314076062723172	3	P26599	1
+Heat shock protein Hsp90, N-terminal [IPR020575]	0.5445307786059435	0.6003578207155856	0.5482677917704684	1.0	0.9346199933373468	4	P14625,Q12931	2
+Peptidase C19, ubiquitin-specific peptidase, DUSP domain [IPR006615]	0.5817246281107373	0.5940689071507274	0.5524660260101089	1.0	0.9346199933373468	3	Q8TEY7	1
+Chromo/chromo shadow domain [IPR000953]	0.4637642733209253	0.5877959112637307	0.5566692887966151	1.0	0.9346199933373468	7	P45973,Q13185,Q8TAQ2	3
+Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219]	0.5793959553333429	0.5861347319899828	0.5577849778326827	1.0	0.9346199933373468	3	O75116	1
+NECAP, PHear domain [IPR012466]	0.7800650054171075	0.5684998501908527	0.569695607396064	1.0	0.9365092901307854	2	Q8NC96	1
+Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]	0.7750090285301359	0.553206999045641	0.5801216748886295	1.0	0.9461942621873244	2	Q32P28	1
+Thioredoxin domain [IPR013766]	0.3983301912111717	0.5496239475257108	0.5825773300165566	1.0	0.9488733344442728	24	Q8IXB1,O95881,P13667,O14530,Q9BS26,Q9H3N1,P07237,P30101,Q15084	9
+Protein Kinase B, pleckstrin homology domain [IPR039026]	0.773203322499078	0.547781979559923	0.5838416135994753	1.0	0.9502694045614892	2	P31749	1
+Ribosome receptor lysine/proline rich [IPR007794]	0.7663416395810747	0.5273481488217988	0.5979518437231457	1.0	0.9538976536295632	2	Q86UP2	1
+Tubulin/FtsZ, GTPase domain [IPR003008]	0.448892220583825	0.525969041805756	0.5989097169430933	1.0	0.9538976536295632	6	Q13885,P07437	2
+Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]	0.448892220583825	0.525969041805756	0.5989097169430933	1.0	0.9538976536295632	6	Q13885,P07437	2
+Chromo domain [IPR023780]	0.4686079342099956	0.5041603972877668	0.6141486674496794	1.0	0.9685290471807784	5	P45973,Q13185	2
+DnaJ domain [IPR001623]	0.4276794633572896	0.5033582591957002	0.6147124128178176	1.0	0.9687635189174788	15	Q96EY1,Q8IXB1,Q13217	3
+Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain [IPR044861]	0.5465155289821346	0.4779162658702675	0.632709803712064	1.0	0.9732920655283674	3	O60568	1
+Clathrin/coatomer adaptor, adaptin-like, N-terminal [IPR002553]	0.430845800018978	0.4710086592192083	0.6376345512412132	1.0	0.9752521898466446	10	Q10567	1
+Sec63 domain [IPR004179]	0.5433259678093989	0.4678368993564732	0.6399012308727339	1.0	0.9752521898466446	3	Q9UGP8	1
+Ras-associating (RA) domain [IPR000159]	0.5429677578466146	0.4667099625773907	0.6407074009967157	1.0	0.9752521898466446	3	Q9Y4G8	1
+Zinc finger, CHHC-type [IPR012996]	0.5428412800416305	0.4663123060201434	0.6409919714990551	1.0	0.9752521898466446	3	P31943	1
+AP complex, mu/sigma subunit [IPR022775]	0.4977542072556913	0.4466313582263184	0.6551412503059229	1.0	0.9788343641877536	4	P61923	1
+RecF/RecN/SMC, N-terminal [IPR003395]	0.4230114437161494	0.4293279114191138	0.6676846073208906	1.0	0.9788361940135972	6	Q9NTJ3,Q96SB8	2
+RNA polymerase Rpb1, domain 1 [IPR007080]	0.5292630057803538	0.4243909286343198	0.6712807353058108	1.0	0.9788361940135972	3	O95602,O14802	2
+RNA polymerase Rpb1, domain 3 [IPR007066]	0.5292630057803538	0.4243909286343198	0.6712807353058108	1.0	0.9788361940135972	3	O95602,O14802	2
+RNA polymerase, N-terminal [IPR006592]	0.5292630057803538	0.4243909286343198	0.6712807353058108	1.0	0.9788361940135972	3	O95602,O14802	2
+RNA polymerase Rpb1, domain 4 [IPR007083]	0.5292630057803538	0.4243909286343198	0.6712807353058108	1.0	0.9788361940135972	3	O95602,O14802	2
+RNA polymerase Rpb1, domain 5 [IPR007081]	0.5292630057803538	0.4243909286343198	0.6712807353058108	1.0	0.9788361940135972	3	O95602,O14802	2
+RNA polymerase, alpha subunit [IPR000722]	0.5292630057803538	0.4243909286343198	0.6712807353058108	1.0	0.9788361940135972	3	O95602,O14802	2
+Band 7 domain [IPR001107]	0.4188587921273373	0.4144779391770155	0.6785241201319105	1.0	0.9806723911857796	6	O94905,Q9UJZ1	2
+Peptidase M16, C-terminal [IPR007863]	0.4137142124352096	0.3970280264305288	0.6913467934337274	1.0	0.9886444205365008	7	O43847,P22695,Q10713,O75439	4
+Peptidase M16, N-terminal [IPR011765]	0.4137142124352096	0.3970280264305288	0.6913467934337274	1.0	0.9886444205365008	7	O43847,P22695,Q10713,O75439	4
+Matrin/U1-C-like, C2H2-type zinc finger [IPR003604]	0.4117928901177136	0.3902411457559047	0.6963582387908258	1.0	0.9886444205365008	7	Q15428,P43243	2
+SMCs flexible hinge [IPR010935]	0.4327548806941289	0.3820752906393749	0.70240551918286	1.0	0.9886444205365008	5	Q9NTJ3,O95347,Q14683,Q9UQE7	4
+Zinc finger C2H2-type [IPR013087]	0.3915691751935304	0.3747465477352951	0.707848970641902	1.0	0.9886444205365008	17	Q96JM3,Q92766,Q96ME7,P98175	4
+Exoribonuclease, phosphorolytic domain 2 [IPR015847]	0.4068773016780943	0.3727749386417957	0.7093159566619869	1.0	0.9886444205365008	6	Q06265	1
+Guanylate kinase/L-type calcium channel beta subunit [IPR008145]	0.4728743783611547	0.3718654537913942	0.709993027426576	1.0	0.9886444205365008	4	Q14168,Q07157	2
+Guanylate kinase-like domain [IPR008144]	0.4728743783611547	0.3718654537913942	0.709993027426576	1.0	0.9886444205365008	4	Q14168,Q07157	2
+Spen paralogue/orthologue C-terminal, metazoa [IPR010912]	0.7063921993499442	0.3627348138137394	0.7168029907634939	1.0	0.9886444205365008	2	Q96T58	1
+Matrin/U1-C, C2H2-type zinc finger [IPR000690]	0.4263606804299451	0.3617129763780307	0.7175665290181359	1.0	0.9886444205365008	5	P43243	1
+LAIKA domain [IPR045353]	0.7042253521126735	0.3573095526361303	0.72086007941436	1.0	0.9886444205365008	2	Q8N163	1
+S1-like RNA binding domain [IPR025223]	0.7042253521126735	0.3573095526361303	0.72086007941436	1.0	0.9886444205365008	2	Q8N163	1
+DBC1/CARP1 catalytically inactive NUDIX hydrolase domain [IPR025954]	0.7042253521126735	0.3573095526361303	0.72086007941436	1.0	0.9886444205365008	2	Q8N163	1
+BURAN domain [IPR045354]	0.7042253521126735	0.3573095526361303	0.72086007941436	1.0	0.9886444205365008	2	Q8N163	1
+Tim44-like domain [IPR007379]	0.6970025279884449	0.339517456674775	0.7342199487135759	1.0	0.9886444205365008	2	Q9BRJ2	1
+Linker histone H1/H5, domain H15 [IPR005818]	0.3913200723327172	0.3213708706761711	0.74792935511628	1.0	0.9886444205365008	6	P16403,Q5SSJ5,P07305,P10412,Q92522	5
+PSP, proline-rich [IPR006568]	0.6883351390393633	0.3187736936103401	0.7498981278552226	1.0	0.9886444205365008	2	Q13435	1
+Zinc finger C2H2 AKAP95-type [IPR034736]	0.6879739978331544	0.3179240148237528	0.7505425757697286	1.0	0.9886444205365008	2	O43823	1
+Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564]	0.4877275902923985	0.3068054202753348	0.7589914823305244	1.0	0.9886444205365008	3	Q13505	1
+Metaxin, glutathione S-transferase domain [IPR033468]	0.4877275902923985	0.3068054202753348	0.7589914823305244	1.0	0.9886444205365008	3	Q13505	1
+Importin-beta, N-terminal domain [IPR001494]	0.3804946336041249	0.304935312358867	0.760415420388334	1.0	0.9886444205365008	14	Q14974,O15397,Q92973,Q96P70,O14787,Q9UI26	6
+WHIM1 domain [IPR028942]	0.4869942196531892	0.304889286204946	0.7604504758943182	1.0	0.9886444205365008	3	Q96T23,Q9UIG0	2
+W2 domain [IPR003307]	0.3845074545506308	0.2991428179430607	0.7648310772021898	1.0	0.9886444205365008	7	Q9Y6E2,P55010,Q13144	3
+Glycoside hydrolase family 31, N-terminal domain [IPR025887]	0.6735283495846875	0.2849225963306114	0.7757034438260719	1.0	0.9886444205365008	2	Q14697	1
+Peptidase S8/S53 domain [IPR000209]	0.6663055254604576	0.2691591574762651	0.787807208408998	1.0	0.9886444205365008	2	O14773	1
+La-type HTH domain [IPR006630]	0.386117136659428	0.245338507808521	0.8061943377249936	1.0	0.9886444205365008	5	Q92615,Q6PKG0,Q4G0J3,P05455	4
+Core histone macro-H2A, macro domain [IPR035796]	0.6540267244492604	0.2435234600215179	0.8075999135541494	1.0	0.9886444205365008	2	Q9P0M6	1
+Importin-alpha, importin-beta-binding domain [IPR002652]	0.4180372921483938	0.2295901987953721	0.818410223679253	1.0	0.9886444205365008	4	O00505,P52294	2
+CID domain [IPR006569]	0.4180276250545072	0.2295682261069669	0.8184272993653487	1.0	0.9886444205365008	4	Q8IWX8	1
+Kinesin motor domain [IPR001752]	0.358630562490301	0.2215510704849614	0.8246633759139981	1.0	0.9886444205365008	10	Q14807,Q12756,O95235,Q02241,O00139,Q9Y496,P33176,Q99661	8
+Reticulon [IPR003388]	0.4101945143228274	0.2121533848477171	0.8319873723953628	1.0	0.9886444205365008	4	O95197	1
+Exoribonuclease, phosphorolytic domain 1 [IPR001247]	0.3495318656114914	0.1989191007336977	0.8423260278601794	1.0	0.9886444205365008	7	Q06265	1
+Serine hydroxymethyltransferase-like domain [IPR039429]	0.6287468400144476	0.1954925150557745	0.8450073967611234	1.0	0.9886444205365008	2	P34897	1
+FCP1 homology domain [IPR004274]	0.6262188515709649	0.191047977556386	0.8484880047044534	1.0	0.9886444205365008	2	Q8WVY7	1
+U2A'/phosphoprotein 32 family A, C-terminal [IPR003603]	0.4378612716763082	0.1909554615564882	0.8485604875137072	1.0	0.9886444205365008	3	P39687,Q92688	2
+Methyltransferase type 11 [IPR013216]	0.6254965691585432	0.1897901982534568	0.8494735369601132	1.0	0.9886444205365008	2	Q6FI81	1
+GUCT [IPR012562]	0.6226074395088516	0.1848128768096044	0.8533758076114559	1.0	0.9886444205365008	2	Q9BQ39	1
+Myb domain [IPR017930]	0.3572187784363053	0.1760088598398231	0.8602869819658845	1.0	0.9886444205365008	5	Q99459,Q8TAQ2	2
+Macro domain [IPR002589]	0.4278474557595431	0.1714399009154916	0.8638778827868803	1.0	0.9886444205365008	3	Q9P0M6	1
+Lens epithelium-derived growth factor, integrase-binding domain [IPR021567]	0.6067172264355392	0.1589796865719293	0.8736848780428377	1.0	0.9886444205365008	2	O75475	1
+PDZ domain [IPR001478]	0.3314688210817702	0.1574624048818561	0.8748804347925354	1.0	0.9886444205365008	16	Q14168,Q07157,Q9Y4G8,P57105,Q14160,O14745	6
+Forkhead-associated (FHA) domain [IPR000253]	0.3295932946709778	0.1489518052655087	0.8815916624394033	1.0	0.9886444205365008	8	Q5SW79	1
+SNF2, N-terminal [IPR000330]	0.3305495012379073	0.1475356744851466	0.8827092236408995	1.0	0.9886444205365008	12	P46100,Q14527	2
+GTP binding domain [IPR006073]	0.3217391304347867	0.1272332537713876	0.8987557865479063	1.0	0.9886444205365008	11	P36915,Q9H089,Q13823,O75616,A4D1E9,Q9NVN8,Q9BVP2,Q9NTK5,Q9BZE4,P55039	10
+SH2 domain [IPR000980]	0.3198621721913945	0.1231132625892315	0.9020174091491592	1.0	0.9886444205365008	11	P46108,P19174	2
+Ran binding domain [IPR000156]	0.3614022406938846	0.1218925832062124	0.9029840895714883	1.0	0.9886444205365008	4	P49792,Q9H6Z4,P43487	3
+2-oxoacid dehydrogenase acyltransferase, catalytic domain [IPR001078]	0.5803539183820892	0.1218558285974503	0.9030131985193206	1.0	0.9886444205365008	2	P10515	1
+Proteasome activator PA28, N-terminal domain [IPR003185]	0.3984826589595446	0.1217994417146082	0.9030578561065044	1.0	0.9886444205365008	3	P61289,Q06323	2
+Proteasome activator PA28, C-terminal domain [IPR003186]	0.3984826589595446	0.1217994417146082	0.9030578561065044	1.0	0.9886444205365008	3	P61289,Q06323	2
+OBG-type guanine nucleotide-binding (G) domain [IPR031167]	0.3210412147505357	0.1078661915078215	0.9141018358732576	1.0	0.9886444205365008	5	P55039,Q9NTK5,Q9BZE4,A4D1E9	4
+SCP2 sterol-binding domain [IPR003033]	0.3869219653179266	0.1053581272682085	0.91609164068285	1.0	0.9886444205365008	3	Q6YN16,P51659	2
+BRCT domain [IPR001357]	0.3025607981699404	0.0926760418072136	0.9261609309478672	1.0	0.9926966782652624	9	P18887	1
+L27 domain [IPR004172]	0.3705145272429761	0.0849574690337697	0.932295203204852	1.0	0.9926966782652624	3	Q14168	1
+L27 domain, C-terminal [IPR014775]	0.3705145272429761	0.0849574690337697	0.932295203204852	1.0	0.9926966782652624	3	Q14168	1
+Zinc finger, GATA-type [IPR000679]	0.3263462233465803	0.0766891562380645	0.93887083120402	1.0	0.9949994204418796	4	Q13330,O94776,Q86YP4	3
+Myosin, N-terminal, SH3-like [IPR004009]	0.3605491329479817	0.0741908929533186	0.9408584922515972	1.0	0.9949994204418796	3	P35579,P35580	2
+B-box, C-terminal [IPR003649]	0.5319609967497351	0.0715073880389216	0.9429939448075808	1.0	0.9959040122990468	2	Q13263	1
+U-box domain [IPR003613]	0.2888147349809599	0.064753642889041	0.948370151555759	1.0	0.9993209633097704	5	Q9UNE7	1
+KOW [IPR005824]	0.2839713936250279	0.0596303034870998	0.9524500826129052	1.0	0.9995586748284716	5	Q92917,P61353	2
+3'-5' exonuclease domain [IPR002562]	0.5113759479956722	0.0564086396766248	0.9550162744492264	1.0	1.0	2	Q01780	1
+DNA-directed DNA polymerase, family B, multifunctional domain [IPR006134]	0.3288727021269867	0.047485847550534	0.962126009630308	1.0	1.0	3	Q07864	1
+DNA-directed DNA polymerase, family B, exonuclease domain [IPR006133]	0.3288727021269867	0.047485847550534	0.962126009630308	1.0	1.0	3	Q07864	1
+Far upstream element-binding protein, C-terminal [IPR015096]	0.4933188876850884	0.0458462281170809	0.9634328128155472	1.0	1.0	2	Q92945	1
+Peptidase M3A/M3B catalytic domain [IPR001567]	0.3244219653179236	0.0445732183581631	0.9644474900903308	1.0	1.0	3	Q9BYT8,P52888	2
+AAA ATPase, AAA+ lid domain [IPR041569]	0.2783446873925053	0.0442065856137788	0.9647397326264304	1.0	1.0	14	Q8NBU5,Q96TA2	2
+WSTF/Acf1/Cbp146 [IPR013136]	0.4868183459732766	0.0425986490352408	0.9660214724280028	1.0	1.0	2	Q9UIG0	1
+WHIM2 domain [IPR028941]	0.4868183459732766	0.0425986490352408	0.9660214724280028	1.0	1.0	2	Q9UIG0	1
+DDT domain [IPR018501]	0.4868183459732766	0.0425986490352408	0.9660214724280028	1.0	1.0	2	Q9UIG0	1
+Pumilio homology domain [IPR033133]	0.4839292163235862	0.0412432371134296	0.967101984746543	1.0	1.0	2	Q14671	1
+Plectin/S10, N-terminal [IPR005326]	0.4828457927049495	0.0407485225564399	0.967496378289108	1.0	1.0	2	P46783	1
+Translation elongation factor EFTu/EF1A, C-terminal [IPR004160]	0.2808095410191541	0.0401712063910363	0.967956633064905	1.0	1.0	4	Q9Y450,P15170,P49411	3
+Zn-dependent metallo-hydrolase, RNA specificity domain [IPR011108]	0.4637053087757322	0.0331507284988178	0.973554389465748	1.0	1.0	2	Q9P2I0	1
+RNA helicase, DEAD-box type, Q motif [IPR014014]	0.2701901079299854	0.0320809989019739	0.9744074562900316	1.0	1.0	22	Q13838,Q8NHQ9,Q9UJV9,Q8TDD1,Q9Y2R4,Q92841,Q86XP3,Q7L014,O00148,Q96GQ7	10
+Domain of unknown function DUF4749 [IPR031847]	0.4543156374142318	0.0301449948693927	0.975951416304411	1.0	1.0	2	Q96HC4	1
+Adenylate kinase, active site lid domain [IPR007862]	0.4492596605272688	0.0287021146055685	0.9771021698524992	1.0	1.0	2	P54819	1
+ATP-citrate lyase/succinyl-CoA ligase [IPR005811]	0.2461149259125408	0.0255952397295006	0.9795801829732748	1.0	1.0	4	Q9P2R7,P53597,Q96I99	3
+Acyltransferase, C-terminal domain [IPR032098]	0.4272300469483561	0.0236689225190774	0.9811166952951784	1.0	1.0	2	Q92604	1
+La protein, xRRM domain [IPR014886]	0.4261466233297249	0.0234683491520788	0.9812766852459188	1.0	1.0	2	P05455	1
+AAA+ ATPase domain [IPR003593]	0.2452034241430782	0.0221477785555821	0.9823300740336358	1.0	1.0	48	Q96TA2,P33527,Q8NBU5,P06576,O15439,P08240,Q96QE3	7
+60S ribosomal protein L10P, insertion domain [IPR040637]	0.413867822318526	0.0214586892868438	0.9828797570413436	1.0	1.0	2	Q9UKD2	1
+Peptidase M16, middle/third domain [IPR032632]	0.3958107620079445	0.019262967682062	0.9846313259520756	1.0	1.0	2	O43847	1
+Zinc finger, PARP-type [IPR001510]	0.3564463705308784	0.0166643626815062	0.9867043776715544	1.0	1.0	2	P49916	1
+RuvB-like, AAA-lid domain [IPR041048]	0.3394727338389286	0.0161302693353526	0.9871304652160644	1.0	1.0	2	Q9Y230	1
+TIP49, P-loop domain [IPR010339]	0.3394727338389286	0.0161302693353526	0.9871304652160644	1.0	1.0	2	Q9Y230	1
+Target SNARE coiled-coil homology domain [IPR000727]	0.2306877504342783	0.0089217463050239	0.9928815708028758	1.0	1.0	10	Q86Y82,Q9UNK0	2