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interpro_active_site/advanced/idx2term.json

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+{}

interpro_active_site/basic/idx2term.json

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+{}

interpro_active_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:bc90ba68f4def90b34a0491f19bd0c1f71f599cfb0a51f99175413280e29ab43
+size 55158

interpro_active_site/df_merge.tsv

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+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_active_site/metrics.json

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+{
+    "type_of_task": "ranksum",
+    "signature_size": 2448,
+    "annotations_size": 49,
+    "title": "Average number of proteins per term",
+    "value": 2.3469387755102042
+}

interpro_active_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C327/C327_val_log2fc"}

interpro_active_site/result.tsv

@@ -0,0 +1,6 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Serine carboxypeptidase, serine active site [IPR018202]	0.9640081799590996	1.983123160758453	0.0473536741248679	0.9071775248957068	0.5312798330552564	3	P10619,Q9H3G5	2
+Ubiquitin-conjugating enzyme, active site [IPR023313]	0.7458043389275487	1.685325638335119	0.0919257618238618	0.9911295347969188	0.5312798330552564	5	P68036,P61086,P61088,Q16763	4
+Ubiquitin-activating enzyme E1, Cys active site [IPR033127]	0.6560327198363882	0.8234583151565861	0.4102474127304918	0.999999999994208	0.9623441537975418	3	Q8TBC4,Q9UBT2	2
+Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]	0.8090760425183988	0.81951554810779	0.4124923348294218	0.9999999999951952	0.9623441537975418	2	Q9NQ88	1
+Cysteine peptidase, cysteine active site [IPR000169]	0.5499688017126064	0.4610989677868746	0.6447276022717008	1.0	0.9623441537975418	3	Q13867	1

interpro_active_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenylosuccinate synthase,  active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, cysteine active site [IPR000169]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADSS", "APEH", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "AURKA", "BLMH", "BUB1", "CAPN1", "CAPN2", "CDK1", "CDK12", "CDK4", "CDK5", "CHEK2", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "FASN", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLUD1", "GSK3B", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "LDHA", "LDHB", "LONP1", "MAP2K1", "MAPK1", "MAPK3", "MDH1", "MDH2", "NEK9", "NME1", "NME2", "OXCT1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKN2", "PLK1", "PREP", "PRKACA", "PRPF4B", "PTK7", "PTPN1", "PTPN11", "RNASET2", "ROCK1", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TPI1", "TPP2", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UMPS", "VRK1", "VRK2"], "leading_proteins": ["BLMH", "CPVL", "CTSA", "TIGAR", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2N", "UBE2S"]}

interpro_binding_site/advanced/idx2term.json

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+{}

interpro_binding_site/basic/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_binding_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:878c1448345036e63f780ea39b80ac5aba10108591ced21a64606532b7ebbce0
+size 55176

interpro_binding_site/df_merge.tsv

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+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_binding_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2448,
+    "annotations_size": 30,
+    "title": "Average number of proteins per term",
+    "value": 3.8
+}

interpro_binding_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C327/C327_val_log2fc"}

interpro_binding_site/result.tsv

@@ -0,0 +1,3 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+PPM-type phosphatase, divalent cation binding [IPR000222]	0.6766148814390899	0.4002324867395243	0.6889852888942936	0.9999999999999994	0.99888310232178	2	Q9H0C8	1
+IQ motif, EF-hand binding site [IPR000048]	0.2758241597095659	0.0453319936683039	0.9638426863831044	1.0	1.0	8	Q13576	1

interpro_binding_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO2", "ACTN1", "ACTN4", "ADSS", "APEX1", "ARG2", "AURKA", "BPNT1", "BUB1", "CALM3", "CALU", "CAPN1", "CAPN2", "CDK1", "CDK12", "CDK4", "CDK5", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPS15", "FKBP10", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQGAP1", "IQGAP2", "LETM1", "MACF1", "MAP2K1", "MAPK1", "MAPK14", "MAPK3", "MCCC1", "METAP2", "MYH10", "MYH9", "MYO1B", "MYO1C", "MYO1D", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXCT1", "PA2G4", "PAK2", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKN2", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "PPM1G", "PRKACA", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "RPS6KA1", "RPS6KA3", "S100A11", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "TKT", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4B", "TUBB6", "UBE3C", "UQCRC2", "VRK1"], "leading_proteins": ["ILKAP", "IQGAP2"]}

interpro_conserved_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Proteasome beta-type subunit, conserved site [IPR016050]"}

interpro_conserved_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Proteasome beta-type subunit, conserved site [IPR016050]", "1": "Chaperonin TCP-1, conserved site [IPR002194]"}

interpro_conserved_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:2e17cbc255b5394d7cd31edc725d7046116167848fa1ca29d494c9f21d51e600
+size 56460

interpro_conserved_site/df_merge.tsv

@@ -0,0 +1,2 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Proteasome beta-type subunit, conserved site [IPR016050]	5	8	2.24415929384879	0.0248221540614264	3.7135922330097086	7.970873786407767	1.4913184573846054	0.1902243906475925	1.515457478026574	0.1681602725795027	1.0170822776023185	0.2455850375425174	1.0	0.0009934566258862	9.25319791909402e-05	1.4599785478071235e-06	1.95600972362446e-06

interpro_conserved_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2448,
+    "annotations_size": 259,
+    "title": "Average number of proteins per term",
+    "value": 2.444015444015444
+}

interpro_conserved_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C327/C327_val_log2fc"}

interpro_conserved_site/result.tsv

@@ -0,0 +1,33 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Proteasome beta-type subunit, conserved site [IPR016050]	0.8533695838363403	2.24415929384879	0.0248221540614264	0.9985116295252592	0.8937329106879885	8	P28070,P49721,P28072,P28074,Q99436	5
+14-3-3 protein, conserved site [IPR023409]	0.6416619193517774	1.3743187687304517	0.1693427420360365	1.0	0.8937329106879885	6	P63104,P61981,P27348,Q04917	4
+Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]	0.958299264104661	1.3605313149364278	0.1736618502445459	1.0	0.8937329106879885	2	Q8N4Q0	1
+Tetraspanin, conserved site [IPR018503]	0.9578904333605892	1.3590181403417827	0.1741408404631963	1.0	0.8937329106879885	2	O43657	1
+Sterol reductase, conserved site [IPR018083]	0.9546197874080132	1.346914390062076	0.1780078064027181	1.0	0.8937329106879885	2	Q14739	1
+Haem oxygenase conserved site [IPR018207]	0.9476696647587912	1.3212051312453368	0.1864329758579987	1.0	0.8937329106879885	2	P30519	1
+Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]	0.9100572363041708	1.182509951113075	0.2370034193964523	1.0	0.8937329106879885	2	Q06481	1
+Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]	0.9100572363041708	1.182509951113075	0.2370034193964523	1.0	0.8937329106879885	2	Q06481	1
+Amyloidogenic glycoprotein,  copper-binding domain conserved site [IPR019744]	0.9100572363041708	1.182509951113075	0.2370034193964523	1.0	0.8937329106879885	2	Q06481	1
+Alpha-D-phosphohexomutase, conserved site [IPR016066]	0.7137014314928323	1.037894833829396	0.2993190189673949	1.0	0.9001815207450597	3	P36871,O95394	2
+Macrophage migration inhibitory factor, conserved site [IPR019829]	0.8589533932951787	0.9963615194308024	0.3190745227541178	1.0	0.9001815207450597	2	P14174	1
+Mini-chromosome maintenance, conserved site [IPR018525]	0.531543511911401	0.8868465737278208	0.3751615089623927	1.0	0.925398388773902	6	Q14566,P33991	2
+Dynamin, GTPase region, conserved site [IPR019762]	0.8201144726083414	0.8580891317395792	0.3908432481587258	1.0	0.931708715132736	2	O00429	1
+HMG box A DNA-binding domain, conserved site [IPR017967]	0.7575633687653354	0.6453450877693543	0.5187035801449609	1.0	0.9955167125898696	2	O15347	1
+DnaJ domain, conserved site [IPR018253]	0.455403771277286	0.5462455362819184	0.5848971686452191	1.0	0.9955167125898696	7	Q96KC8,Q8WXX5	2
+Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]	0.7215862632870034	0.5311821571386203	0.5952925562512266	1.0	0.9955167125898696	2	P01889	1
+Aldo/keto reductase, conserved site [IPR018170]	0.6896974652493919	0.4367867546242631	0.6622660057305039	1.0	0.9955167125898696	2	P15121	1
+Annexin repeat, conserved site [IPR018252]	0.4233900359631164	0.3761388657519013	0.7068136616128258	1.0	0.9955167125898696	5	P08133,P50995	2
+Helix-hairpin-helix motif, class 2 [IPR008918]	0.6647587898610036	0.3683116978046766	0.712640831076107	1.0	0.9955167125898696	2	P39748	1
+XPG conserved site [IPR019974]	0.6647587898610036	0.3683116978046766	0.712640831076107	1.0	0.9955167125898696	2	P39748	1
+Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]	0.6582174979558524	0.3512165394660315	0.7254259028340944	1.0	0.9955167125898696	2	P29692	1
+Ubiquitin-activating enzyme E1, conserved site [IPR018074]	0.6557645134914208	0.3449034977971063	0.7301669209237991	1.0	0.9955167125898696	2	Q9UBT2	1
+Chaperonin TCP-1, conserved site [IPR002194]	0.3741803278688584	0.2458239065735731	0.8058185500376567	1.0	0.9955167125898696	8	Q99832,P17987,P50990,P50991,P49368,P78371,P40227	7
+Aldehyde dehydrogenase, glutamic acid active site [IPR029510]	0.3568066667072523	0.2127146211696998	0.8315495617063258	1.0	0.9955167125898696	7	P30837	1
+Cullin, conserved site [IPR016157]	0.3536635284486299	0.1842601484002159	0.8538093755614968	1.0	0.9955167125898696	5	Q13617,Q13616,Q13618,Q93034	4
+Thioredoxin, conserved site [IPR017937]	0.3497572694849473	0.166422849334545	0.867824193518334	1.0	0.9955167125898696	9	Q9H1E5,P07237	2
+FERM conserved site [IPR019747]	0.3303322535788665	0.160910835455258	0.872163628058799	1.0	0.9955167125898696	6	P35241,P15311	2
+RNA polymerase, beta subunit, conserved site [IPR007121]	0.555192150449723	0.1377990743308771	0.8903992159578815	1.0	0.9955167125898696	2	Q9H9Y6	1
+Ubiquitin specific protease, conserved site [IPR018200]	0.328747635063101	0.1197486208164367	0.9046822836007656	1.0	0.9955167125898696	9	Q96K76	1
+Heat shock protein Hsp90, conserved site [IPR019805]	0.3516487904278492	0.0570293292235679	0.9545218318122428	1.0	0.9955167125898696	3	P07900	1
+Chromo domain, conserved site [IPR023779]	0.2693409742120357	0.055562489770421	0.9556903471460544	1.0	0.9955167125898696	5	P83916,Q99549,O14646,Q13185	4
+Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]	0.3487326246933863	0.0077447098290827	0.9938206773727132	1.0	1.0	2	P11586	1

interpro_conserved_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Amyloidogenic glycoprotein,  copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific,  conserved site [IPR031303]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P,  conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor, T-box, conserved site [IPR018186]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR1A", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AK1", "AK2", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "APEX1", "APLP2", "APP", "ATAD1", "ATP5C1", "ATP5O", "BAG6", "BAX", "BAZ1A", "BAZ1B", "BCAT2", "BDH2", "BLM", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD2", "BRD4", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CBR1", "CBX1", "CBX3", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDH2", "CDKAL1", "CHAF1B", "CHD1", "CHD4", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1C", "CPOX", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX40", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJC1", "DNAJC11", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DRG1", "DRG2", "DSC3", "DSG2", "DST", "DTYMK", "DYNLL1", "EARS2", "ECH1", "ECHS1", "ECI1", "ECI2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "ENO1", "EPB41", "EPB41L2", "EPDR1", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXC1", "FUCA1", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLO1", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GRWD1", "GSPT1", "GTF3C2", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB3", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IDH1", "IDH2", "IDH3A", "IDH3B", "ILVBL", "IMPDH2", "IQGAP1", "IQGAP2", "IVD", "KDM2A", "KDSR", "KIF11", "KIF18A", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MAPK3", "MARS", "MAT2A", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME2", "MGA", "MGST2", "MIF", "MPHOSPH8", "MPI", "MPP6", "MPST", "MRPL24", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFV1", "NEFM", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD2", "NSF", "NUBP2", "NUBPL", "NUDT1", "NUDT5", "NUP153", "NUP37", "NVL", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF14", "PHF3", "PHF8", "PHGDH", "PHIP", "PI4KB", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PNP", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "RACK1", "RAE1", "RANBP2", "RARS", "RBBP7", "RCL1", "RDH13", "RDX", "RIDA", "RNF114", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "S100A10", "S100A11", "SART1", "SBDS", "SCAF11", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC27A4", "SLIT2", "SMARCA4", "SMU1", "SNRNP40", "SPATA5", "SPATA5L1", "SPTBN1", "SRCAP", "SRM", "STMN1", "STX12", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "TBL3", "TCP1", "TK1", "TLN1", "TMX1", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM21", "TRIM25", "TRIM27", "TRIM28", "TRIM33", "TRIP13", "TSFM", "TSPAN3", "TSPAN6", "TUBB", "TUBB2A", "TUBB2B", "TUBB4B", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UHRF1", "USP10", "USP14", "USP15", "USP33", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZMYND8"], "leading_proteins": ["AKR1B1", "ALDH1B1", "ANXA11", "ANXA6", "APLP2", "CBX1", "CBX3", "CCT2", "CCT3", "CCT4", "CCT6A", "CCT7", "CCT8", "CHD1", "CUL1", "CUL2", "CUL3", "CUL5", "DNAJC1", "DNAJC9", "DNM1L", "EEF1D", "EZR", "FEN1", "HLA-B", "HMGB3", "HMOX2", "HSP90AA1", "LBR", "MCM4", "MCM6", "MIF", "MPHOSPH8", "MTHFD1", "P4HB", "PGM1", "PGM3", "POLR1B", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "RDX", "TCP1", "TMX4", "TSPAN6", "UBA2", "USP47", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2"]}

interpro_domain/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_domain/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Proteasome component (PCI) domain [IPR000717]", "1": "Thioredoxin domain [IPR013766]", "2": "Chromo domain [IPR023780]", "3": "Importin-beta, N-terminal domain [IPR001494]"}

interpro_domain/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:6851006510e3e85d1698a7fb4fd101ab2630dbbfa14abc7c4b808565f19302a3
+size 79301

interpro_domain/df_merge.tsv

@@ -0,0 +1,6 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	3	5	2.296208651574636	0.0216639541119529	2.813106796116505	6.104368932038835	1.6405397264547834	0.1100883340733615	1.2852875686886795	0.8042848477475721	1.100790504333474	0.1612592696854457	1.0	0.0014481500629001	0.0001673348473236	0.0001196735467101	0.0001402534450405
+Immunoglobulin subtype 2 [IPR003598]	1	6	2.112428427542985	0.0346497188556882	2.8106796116504853	8.04126213592233	0.1764352420775828	0.5005828106358552	2.0581551085254395	2.677802743524345	1.0491539805619012	0.3137632145774063	1.0	1.0	0.1343256297607796	0.4694136657857993	0.8393448331715895
+Immunoglobulin subtype [IPR003599]	1	6	2.112428427542985	0.0346497188556882	2.9684466019417477	8.483009708737864	0.1381371967634491	0.4928258967784709	2.271921156707309	2.9216637549507847	1.0756254869730633	0.312999744433737	1.0	1.0	0.2320613798556079	0.661178430931402	0.9481889797526988
+Glutathione S-transferase, N-terminal [IPR004045]	1	6	2.1069288854850696	0.0351237443400265	2.4635922330097086	7.354368932038835	0.1379245375050955	0.5007649291980636	1.692684060559357	0.9479949918991396	0.9964823876403148	0.2990443112345751	1.0	0.0516364610584135	0.0045656876518621	0.0255685736411364	0.0131100293828519
+FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]	4	7	1.9786666337721213	0.047853551995094	3.1262135922330097	10.111650485436892	0.9686720267359892	0.3700536707457866	1.7316562118191232	1.203619216216406	0.9607394322697528	0.3108814801432357	0.0314287256441149	0.0607401038440192	0.1157837219692003	7.042870611585469e-06	0.0002190726437552

interpro_domain/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2448,
+    "annotations_size": 2188,
+    "title": "Average number of proteins per term",
+    "value": 2.053930530164534
+}

interpro_domain/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C327/C327_val_log2fc"}

interpro_domain/result.tsv

@@ -0,0 +1,202 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	0.8951088196090089	2.296208651574636	0.0216639541119529	1.0	0.8648875702126152	5	O15173,O43169,Q9UMX5	3
+Aminopeptidase N-like , N-terminal domain [IPR045357]	0.9118988433968308	2.2093147292874575	0.0271527573945049	1.0	0.8648875702126152	4	Q9UIQ6,P55786	2
+Peptidase M1, membrane alanine aminopeptidase [IPR014782]	0.9118988433968308	2.2093147292874575	0.0271527573945049	1.0	0.8648875702126152	4	Q9UIQ6,P55786	2
+Polyketide synthase, enoylreductase domain [IPR020843]	0.8876231555953777	2.114799302472403	0.0344470563607692	1.0	0.8648875702126152	4	Q8N4Q0,Q99536	2
+Immunoglobulin subtype 2 [IPR003598]	0.8121477184613126	2.1124284275429854	0.0346497188556882	1.0	0.8648875702126152	6	P35613	1
+Immunoglobulin subtype [IPR003599]	0.8121477184613126	2.1124284275429854	0.0346497188556882	1.0	0.8648875702126152	6	P35613	1
+Glutathione S-transferase, N-terminal [IPR004045]	0.8108347347574727	2.1069288854850696	0.0351237443400265	1.0	0.8648875702126152	6	Q9H7Z7	1
+FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]	0.7854168605046101	1.9786666337721217	0.047853551995094	1.0	0.8648875702126152	7	Q96AY3,P26885,Q02790,Q13451	4
+Alcohol dehydrogenase-like, C-terminal [IPR013149]	0.8076868021222101	1.9428256098989765	0.0520372324904081	1.0	0.8648875702126152	5	Q8N8N7,Q8N4Q0	2
+Dynamin, N-terminal [IPR045063]	0.7314828059599056	1.768743629676775	0.0769366677289857	1.0	0.8648875702126152	6	Q8IWA4,P50570,Q9H223,O00429	4
+Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]	0.7314828059599056	1.768743629676775	0.0769366677289857	1.0	0.8648875702126152	6	Q8IWA4,P50570,Q9H223,O00429	4
+LEM domain [IPR003887]	0.7622992245331079	1.7544955248657654	0.0793456360490634	1.0	0.8648875702126152	5	Q9Y2U8,Q86XL3	2
+Ubiquitin-associated domain [IPR015940]	0.7134016569607707	1.6254364907486485	0.1040695858731992	1.0	0.8648875702126152	9	Q14157,P54727,Q04323,Q9NRR5	4
+Glutathione S-transferase, C-terminal-like [IPR010987]	0.7135880100120883	1.6060337709179282	0.1082664900711609	1.0	0.8648875702126152	10	P78417,Q9Y696,O43324,Q9H7Z7	4
+Proteasome alpha-subunit, N-terminal domain [IPR000426]	0.6953662217783737	1.588852101600298	0.1120937872086802	1.0	0.8648875702126152	7	O14818,P25787,P60900,P25789	4
+GMP phosphodiesterase, delta subunit [IPR008015]	0.9901880621422732	1.4786327318563135	0.1392384996640565	1.0	0.8648875702126152	2	O43924	1
+Cold shock domain [IPR011129]	0.7262684124386155	1.4662435018710267	0.1425819612034971	1.0	0.8648875702126152	4	P16989,O75534,P67809	3
+Cold-shock protein, DNA-binding [IPR002059]	0.7262684124386155	1.4662435018710267	0.1425819612034971	1.0	0.8648875702126152	4	P16989,O75534,P67809	3
+Cold-shock (CSD) domain [IPR019844]	0.7262684124386155	1.4662435018710267	0.1425819612034971	1.0	0.8648875702126152	4	P16989,O75534,P67809	3
+Alcohol dehydrogenase, N-terminal [IPR013154]	0.8261356259970132	1.4656632926617614	0.1427400390681867	1.0	0.8648875702126152	3	Q8N4Q0	1
+Glutamine amidotransferase [IPR017926]	0.7201094803251438	1.4409677477456135	0.1495937946723993	1.0	0.8648875702126152	4	Q9NRF8	1
+TRAM/LAG1/CLN8 homology domain [IPR006634]	0.969337694194604	1.4014007823790728	0.1610942584562245	1.0	0.8648875702126152	2	Q96G23	1
+Peptidase M3A/M3B catalytic domain [IPR001567]	0.8068115422780148	1.392048674598286	0.1639076589105683	1.0	0.8648875702126152	3	P52888	1
+14-3-3 domain [IPR023410]	0.6416619193517774	1.3743187687304517	0.1693427420360365	1.0	0.8648875702126152	6	P63104,P61981,P27348,Q04917	4
+ERAP1-like C-terminal domain [IPR024571]	0.9611610793131647	1.3711246996212465	0.1703360865130958	1.0	0.8648875702126152	2	P55786	1
+Immunoglobulin-like domain [IPR007110]	0.6519826938808686	1.353153140853553	0.1760067117321382	1.0	0.8689133306919967	9	P35613	1
+Phosphoribosyltransferase domain [IPR000836]	0.6362450271129672	1.3502692053350298	0.1769296464705556	1.0	0.8689133306919967	6	P00492,P11908,P07741,O60256	4
+GOLD domain [IPR009038]	0.6977945595687639	1.3492570519727216	0.1772544153576873	1.0	0.8689133306919967	4	Q9BVK6,Q9H3P7	2
+Sorting nexin Vps5-like, C-terminal [IPR015404]	0.6963993453355046	1.3435184232006463	0.1791041645987616	1.0	0.8689133306919967	4	Q13596,Q9Y5X3,O60749	3
+Peptidase M28 [IPR007484]	0.7905930470347494	1.3301940706260835	0.183454337273043	1.0	0.8773413736068045	3	Q7Z2K6,Q969V3	2
+Heat shock chaperonin-binding [IPR006636]	0.7893660531697277	1.3255134152351795	0.1850009229368345	1.0	0.8813549861732665	3	P54727,Q9NRR5	2
+THIF-type NAD/FAD binding fold [IPR000594]	0.6218008169883467	1.2860707263447184	0.1984183794553073	1.0	0.8833296973642464	6	Q9UBT2,Q9UBE0,A0AVT1,Q8TBC4	4
+Oxidoreductase, N-terminal domain [IPR041694]	0.9288634505314812	1.2517446250405329	0.2106629337306531	1.0	0.8833296973642464	2	Q8N8N7	1
+EB1, C-terminal [IPR004953]	0.9255928045789044	1.2396849174961009	0.2150919579197299	1.0	0.8833296973642464	2	Q15555	1
+Thioredoxin-like fold [IPR012336]	0.9235486508585458	1.2321512764819915	0.2178925800528519	1.0	0.8833296973642464	2	Q8NBF2	1
+Glutathione S-transferase, C-terminal [IPR004046]	0.6219009941176483	1.2188946443526851	0.2228841826725547	1.0	0.8849206171321462	9	P78417,O43324	2
+Reticulon [IPR003388]	0.917825020441539	1.21107332755495	0.2258673027148574	1.0	0.8849206171321462	2	O95197	1
+Proteasome component (PCI) domain [IPR000717]	0.6528961062905488	1.2078256989355234	0.22711431418224	1.0	0.8849206171321462	17	Q9UNS2,Q9UBW8,Q9BT78,Q7L2H7,O00231,O43242,P61201,Q9Y262,Q99627	9
+Pancreatic trypsin inhibitor Kunitz domain [IPR002223]	0.9100572363041708	1.182509951113075	0.2370034193964523	1.0	0.8849206171321462	2	Q06481	1
+Amyloidogenic glycoprotein, E2 domain [IPR024329]	0.9100572363041708	1.182509951113075	0.2370034193964523	1.0	0.8849206171321462	2	Q06481	1
+Amyloidogenic glycoprotein, copper-binding [IPR011178]	0.9100572363041708	1.182509951113075	0.2370034193964523	1.0	0.8849206171321462	2	Q06481	1
+Amyloidogenic glycoprotein, extracellular [IPR008154]	0.9100572363041708	1.182509951113075	0.2370034193964523	1.0	0.8849206171321462	2	Q06481	1
+Beta-amyloid precursor protein C-terminal [IPR019543]	0.9100572363041708	1.182509951113075	0.2370034193964523	1.0	0.8849206171321462	2	Q06481	1
+Amyloidogenic glycoprotein, heparin-binding [IPR015849]	0.9100572363041708	1.182509951113075	0.2370034193964523	1.0	0.8849206171321462	2	Q06481	1
+Septin-type guanine nucleotide-binding (G) domain [IPR030379]	0.6234138354482203	1.1645675509621016	0.2441940850074784	1.0	0.9039983949492114	5	Q16181,Q92599,Q9UHD8,Q9NVA2	4
+CAP Gly-rich domain [IPR000938]	0.738160847840456	1.130467036415814	0.2582794807577251	1.0	0.924427369672938	3	Q14203	1
+Exportin-2, central domain [IPR013713]	0.7361963190183998	1.123010294104759	0.2614331224984818	1.0	0.924427369672938	3	O95373,P55060	2
+CTP synthase GATase domain [IPR033828]	0.8834832379394951	1.0852618252913953	0.2778057084575662	1.0	0.924427369672938	2	Q9NRF8	1
+CTP synthase, N-terminal [IPR017456]	0.8834832379394951	1.0852618252913953	0.2778057084575662	1.0	0.924427369672938	2	Q9NRF8	1
+MRH domain [IPR044865]	0.7260414997668647	1.0845204249331992	0.2781341159028097	1.0	0.924427369672938	3	P20645	1
+Immunoglobulin C1-set [IPR003597]	0.7218813905930443	1.0687821301768543	0.2851678533157802	1.0	0.924427369672938	3	P10321,P01889	2
+MHC class I-like antigen recognition-like [IPR011161]	0.7218813905930443	1.0687821301768543	0.2851678533157802	1.0	0.924427369672938	3	P10321,P01889	2
+MHC class I, alpha chain, C-terminal [IPR010579]	0.7218813905930443	1.0687821301768543	0.2851678533157802	1.0	0.924427369672938	3	P10321,P01889	2
+MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]	0.7218813905930443	1.0687821301768543	0.2851678533157802	1.0	0.924427369672938	3	P10321,P01889	2
+Alpha-D-phosphohexomutase, alpha/beta/alpha domain I [IPR005844]	0.7137014314928323	1.037894833829396	0.2993190189673949	1.0	0.924427369672938	3	P36871,O95394	2
+Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]	0.7010224948875311	0.9901986813562098	0.322077016959611	1.0	0.9296893312765552	3	O15460,P13674	2
+Dynamin, GTPase domain [IPR001401]	0.6954705590928475	0.969392609698246	0.3323493382314813	1.0	0.937946265685226	3	O00429	1
+Proteasome activator PA28, N-terminal domain [IPR003185]	0.6952965235173725	0.9687412655747584	0.3326742980019586	1.0	0.937946265685226	3	P61289,Q9UL46	2
+Proteasome activator PA28, C-terminal domain [IPR003186]	0.6952965235173725	0.9687412655747584	0.3326742980019586	1.0	0.937946265685226	3	P61289,Q9UL46	2
+Post-SET domain [IPR003616]	0.6042687590210357	0.966579937716344	0.3337540678308897	1.0	0.937946265685226	4	O15047	1
+EH domain [IPR000261]	0.6026127018989045	0.9599014049983292	0.3371048390305105	1.0	0.9404553801144	4	Q9H223	1
+Methyltransferase type 11 [IPR013216]	0.843008994276371	0.9391704349135004	0.3476432458427221	1.0	0.9459294375499098	2	Q8N6R0	1
+TOG domain [IPR034085]	0.5434830041605718	0.9390169782572032	0.3477220273515766	1.0	0.9459294375499098	6	O00410,Q8TEX9,Q86Y56	3
+Chaperone DnaJ, C-terminal [IPR002939]	0.675664621676894	0.8956476630585712	0.3704409709823864	1.0	0.9492443376267692	3	P25685,P31689	2
+MCM, AAA-lid domain [IPR041562]	0.531543511911401	0.8868465737278208	0.3751615089623927	1.0	0.9555918295805766	6	Q14566,P33991	2
+MCM OB domain [IPR033762]	0.531543511911401	0.8868465737278208	0.3751615089623927	1.0	0.9555918295805766	6	Q14566,P33991	2
+MCM N-terminal domain [IPR027925]	0.531543511911401	0.8868465737278208	0.3751615089623927	1.0	0.9555918295805766	6	Q14566,P33991	2
+MCM domain [IPR001208]	0.531543511911401	0.8868465737278208	0.3751615089623927	1.0	0.9555918295805766	6	Q14566,P33991	2
+ERM family, FERM domain C-lobe [IPR041789]	0.6707566462167682	0.8775064494491006	0.380211617323396	1.0	0.9610674818231668	3	P35241,P15311	2
+CS domain [IPR007052]	0.5340873832203961	0.8748587342555826	0.381650774559189	1.0	0.9620413533819188	7	Q9Y266,Q9HB71	2
+SET domain [IPR001214]	0.5306958213630655	0.8601216634127479	0.389721980699071	1.0	0.9620515695336658	7	Q9H7B4,O15047	2
+Dynamin stalk domain [IPR000375]	0.8201144726083414	0.8580891317395792	0.3908432481587258	1.0	0.9620515695336658	2	O00429	1
+Dynamin GTPase effector [IPR003130]	0.8201144726083414	0.8580891317395792	0.3908432481587258	1.0	0.9620515695336658	2	O00429	1
+GTPase effector domain [IPR020850]	0.8201144726083414	0.8580891317395792	0.3908432481587258	1.0	0.9620515695336658	2	O00429	1
+Glucosamine/galactosamine-6-phosphate isomerase [IPR006148]	0.8192968111201975	0.8552193334848986	0.392429735021963	1.0	0.9620515695336658	2	O95336	1
+Peptidase M24 [IPR000994]	0.5450887723711735	0.8343914274400334	0.4040604463884025	1.0	0.9703531715224752	5	Q9NQW7,P50579	2
+4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896]	0.6552120018811592	0.8204636515272599	0.4119518423343886	1.0	0.9757359983707682	3	Q16134	1
+Ribose-phosphate pyrophosphokinase, N-terminal domain [IPR029099]	0.6446861134175325	0.7822428729611759	0.4340718528027918	1.0	0.9862973703863877	3	O60256	1
+CYRIA/CYRIB, Rac1 binding domain [IPR009828]	0.7980376124284567	0.7813316394823754	0.4346074659337167	1.0	0.9862973703863877	2	Q9NUQ9	1
+Domain of unknown function DUF5600 [IPR040990]	0.7759607522485716	0.7062992694401276	0.4800020476619067	1.0	0.9915431271162686	2	Q9H223	1
+EH domain-containing protein, N-terminal [IPR031692]	0.7759607522485716	0.7062992694401276	0.4800020476619067	1.0	0.9915431271162686	2	Q9H223	1
+Translation initiation factor IF2/IF5 domain [IPR002735]	0.772281275551926	0.6939860054877821	0.4876909852719391	1.0	0.9915431271162686	2	P55010	1
+W2 domain [IPR003307]	0.4864186565191066	0.6717597768234644	0.501736639387897	1.0	0.9915431271162686	7	Q04637,P78344,P55010	3
+Ubiquitin-conjugating enzyme E2 [IPR000608]	0.4813974404439723	0.6510047482097177	0.5150434218047857	1.0	0.9915431271162686	7	P68036,P61086,P61088,Q16763	4
+Rab-GTPase-TBC domain [IPR000195]	0.5224485834924935	0.6474508641265027	0.5173401855943549	1.0	0.9915431271162686	4	O60343	1
+PWWP domain [IPR000313]	0.4802602825719124	0.6463254577182911	0.5180686042588158	1.0	0.9915431271162686	7	P51858	1
+Mad3/Bub1 homology region 1 [IPR013212]	0.7571545380212623	0.6440086303934887	0.519569837568544	1.0	0.9915431271162686	2	O60566	1
+Sorting nexin, N-terminal [IPR005329]	0.7420278004906005	0.5951615147843654	0.5517355127133812	1.0	0.9915431271162686	2	O60749	1
+RBM3/CIRBP, RNA recognition motif [IPR034278]	0.7375306623058093	0.5808766496103656	0.5613235908086616	1.0	0.9915431271162686	2	Q14011	1
+Zinc finger, RanBP2-type [IPR001876]	0.4673959414954854	0.5730034570058915	0.5666423532875244	1.0	0.9915431271162686	8	Q92804	1
+Ubiquitin-like domain [IPR000626]	0.4819425531904742	0.5527139163631303	0.5804593225329864	1.0	0.9915431271162686	12	Q15813,P54727,Q9NRR5,P46379	4
+Guanylate kinase-like domain [IPR008144]	0.5766296381488423	0.546273991270659	0.5848776116647698	1.0	0.9915431271162686	3	Q9UDY2	1
+Guanylate kinase/L-type calcium channel beta subunit [IPR008145]	0.5766296381488423	0.546273991270659	0.5848776116647698	1.0	0.9915431271162686	3	Q9UDY2	1
+Cation-transporting P-type ATPase, N-terminal [IPR004014]	0.5730061349693303	0.5344086882464175	0.5930588092272535	1.0	0.9915431271162686	3	P20020,P05023	2
+Cation-transporting P-type ATPase, C-terminal [IPR006068]	0.5730061349693303	0.5344086882464175	0.5930588092272535	1.0	0.9915431271162686	3	P20020,P05023	2
+Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547]	0.7203597710547879	0.5274240511277867	0.5978991451877493	1.0	0.9915431271162686	2	O15460	1
+Alpha-D-phosphohexomutase, C-terminal [IPR005843]	0.7134096484055645	0.5063115587925261	0.6126379498975438	1.0	0.9915431271162686	2	O95394	1
+Alpha-D-phosphohexomutase, alpha/beta/alpha domain II [IPR005845]	0.7134096484055645	0.5063115587925261	0.6126379498975438	1.0	0.9915431271162686	2	P36871	1
+Alpha-D-phosphohexomutase, alpha/beta/alpha domain III [IPR005846]	0.7134096484055645	0.5063115587925261	0.6126379498975438	1.0	0.9915431271162686	2	P36871	1
+PITH domain [IPR010400]	0.7130008176614926	0.5050795353794036	0.6135029743326263	1.0	0.9915431271162686	2	O43396	1
+S100/CaBP-9k-type, calcium binding, subdomain [IPR013787]	0.5634789753745186	0.503630743828634	0.6145208841482159	1.0	0.9915431271162686	3	Q99584	1
+PIN domain [IPR002716]	0.7113654946852048	0.5001626341158011	0.6169605664421458	1.0	0.9915431271162686	2	Q9ULX3	1
+Zinc finger, LIM-type [IPR001781]	0.4411313049094185	0.4352665515494297	0.6633689606582076	1.0	0.9915431271162686	5	Q15942,O00151,Q14847	3
+26S proteasome regulatory subunit Rpn7, N-terminal [IPR045135]	0.6839738348323847	0.4206278686953146	0.6740268402031799	1.0	0.9915431271162686	2	Q15008	1
+Peptidase M16, N-terminal [IPR011765]	0.419080007017014	0.4094875975936479	0.6821818666271686	1.0	0.9915431271162686	7	Q10713,Q5JRX3	2
+Peptidase M16, C-terminal [IPR007863]	0.419080007017014	0.4094875975936479	0.6821818666271686	1.0	0.9915431271162686	7	Q10713,Q5JRX3	2
+Heat shock protein DnaJ, cysteine-rich domain [IPR001305]	0.6753883892068739	0.3968758802918464	0.6914589913832323	1.0	0.9915431271162686	2	P31689	1
+EGF-like domain [IPR000742]	0.6745707277187301	0.3946450145856237	0.6931048875626578	1.0	0.9915431271162686	2	P11047	1
+Rhodanese-like domain [IPR001763]	0.6708912510220826	0.3846747864791165	0.7004783778783117	1.0	0.9915431271162686	2	Q8NCN5	1
+WHEP-TRS domain [IPR000738]	0.440261865793777	0.3688725492803605	0.7122227252050461	1.0	0.9915431271162686	4	P07814,P23381,P41250	3
+XPG-I domain [IPR006086]	0.6647587898610036	0.3683116978046766	0.712640831076107	1.0	0.9915431271162686	2	P39748	1
+XPG, N-terminal [IPR006085]	0.6647587898610036	0.3683116978046766	0.712640831076107	1.0	0.9915431271162686	2	P39748	1
+Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain [IPR014038]	0.6582174979558524	0.3512165394660315	0.7254259028340944	1.0	0.9915431271162686	2	P29692	1
+Elongation factor 1 beta central acidic region, eukaryote [IPR018940]	0.6582174979558524	0.3512165394660315	0.7254259028340944	1.0	0.9915431271162686	2	P29692	1
+Ubiquitin-activating enzyme E1, four-helix bundle [IPR032420]	0.6557645134914207	0.3449034977971063	0.7301669209237991	1.0	0.9915431271162686	2	A0AVT1	1
+Ubiquitin-activating enzyme E1, C-terminal [IPR018965]	0.6557645134914207	0.3449034977971063	0.7301669209237991	1.0	0.9915431271162686	2	A0AVT1	1
+Ubiquitin-activating enzyme E1, FCCH domain [IPR032418]	0.6557645134914207	0.3449034977971063	0.7301669209237991	1.0	0.9915431271162686	2	A0AVT1	1
+Ubiquitin-activating enzyme, SCCH domain [IPR019572]	0.6557645134914207	0.3449034977971063	0.7301669209237991	1.0	0.9915431271162686	2	A0AVT1	1
+Sec23/Sec24, trunk domain [IPR006896]	0.5082509058594915	0.33933995349468	0.7343536477461197	1.0	0.9915431271162686	3	Q15436	1
+Zinc finger, Sec23/Sec24-type [IPR006895]	0.5082509058594915	0.33933995349468	0.7343536477461197	1.0	0.9915431271162686	3	Q15436	1
+Sec23/Sec24, helical domain [IPR006900]	0.5082509058594915	0.33933995349468	0.7343536477461197	1.0	0.9915431271162686	3	Q15436	1
+Sec23/Sec24 beta-sandwich [IPR012990]	0.5082509058594915	0.33933995349468	0.7343536477461197	1.0	0.9915431271162686	3	Q15436	1
+Domain of unknown function DUF4749 [IPR031847]	0.6508585445625574	0.3324403642043564	0.739556763735826	1.0	0.9915431271162686	2	O00151	1
+Butyrophylin-like, SPRY domain [IPR003879]	0.4257827963737599	0.3268624020576562	0.7437719592581258	1.0	0.9915431271162686	4	P19474	1
+SPRY-associated [IPR006574]	0.4257827963737599	0.3268624020576562	0.7437719592581258	1.0	0.9915431271162686	4	P19474	1
+Sterile alpha motif domain [IPR001660]	0.6479967293540537	0.3252719433623881	0.74497526326796	1.0	0.9915431271162686	2	Q9Y6Y8	1
+Proteasomal ATPase OB C-terminal domain [IPR032501]	0.406058125255834	0.322012524925736	0.747443205968966	1.0	0.9915431271162686	5	P17980,P62191,P62195,P62333	4
+MIT domain [IPR007330]	0.495795827884018	0.3061985050707939	0.7594535105601083	1.0	0.9915431271162686	3	Q8N0X7	1
+FYVE zinc finger [IPR000306]	0.4912065439672884	0.2943985740525828	0.768453356397941	1.0	0.9915431271162686	3	Q7Z3T8,Q9P2R3	2
+Zinc finger, FYVE-related [IPR017455]	0.4912065439672884	0.2943985740525828	0.768453356397941	1.0	0.9915431271162686	3	Q7Z3T8,Q9P2R3	2
+Tim44-like domain [IPR007379]	0.6336876533115359	0.290586671368198	0.7713674551127563	1.0	0.9915431271162686	2	O43615	1
+Beta-adaptin appendage, C-terminal subdomain [IPR015151]	0.4842535787321151	0.2769588056634031	0.7818117375560405	1.0	0.9915431271162686	3	Q10567,O00203	2
+Fibronectin type II domain [IPR000562]	0.6165167620605143	0.2516119688006722	0.8013410064429218	1.0	0.9915431271162686	2	P11717	1
+Myosin tail [IPR002928]	0.6046606704824281	0.226459746023037	0.8208438640128775	1.0	0.9915431271162686	2	P35579	1
+PurM-like, C-terminal domain [IPR010918]	0.4580777096114616	0.2162675953216608	0.828779166538653	1.0	0.9915431271162686	3	P22102,O15067	2
+Ras GTPase-activating domain [IPR001936]	0.4579907075056612	0.2160794447922007	0.8289258219187838	1.0	0.9915431271162686	3	Q13576	1
+Cyclin-like [IPR013763]	0.5932134096484136	0.2035817592295734	0.8386803486492207	1.0	0.9915431271162686	2	P14635	1
+DnaJ domain [IPR001623]	0.3750180682461551	0.1899793797238692	0.8493252888566918	1.0	0.9915431271162686	12	P25685,Q96KC8,Q8WXX5	3
+Cullin protein, neddylation domain [IPR019559]	0.3536635284486299	0.1842601484002159	0.8538093755614968	1.0	0.9915431271162686	5	Q13617,Q13616,Q13618,Q93034	4
+Cullin homology domain [IPR016158]	0.3536635284486299	0.1842601484002159	0.8538093755614968	1.0	0.9915431271162686	5	Q13617,Q13616,Q13618,Q93034	4
+ABC-transporter extension domain [IPR032781]	0.5813573180703273	0.1813734489821493	0.8560744578764121	1.0	0.9915431271162686	2	Q9NUQ8	1
+Thioredoxin domain [IPR013766]	0.4066735811468001	0.1752373065793793	0.8608931714358934	1.0	0.9915431271162686	20	Q9H1E5,P07237,O43396,Q8NBF2,P30041,Q6DKJ4,Q6ZRP7	7
+High mobility group box domain [IPR009071]	0.3507147272040394	0.168738232181561	0.8660025450153814	1.0	0.9915431271162686	9	O15347,O96028	2
+FERM domain [IPR000299]	0.3303322535788665	0.160910835455258	0.872163628058799	1.0	0.9915431271162686	6	P35241,P15311	2
+Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant [IPR000866]	0.3518821603927978	0.1571999382724752	0.8750872769477853	1.0	0.9915431271162686	4	Q13162,P30041,P32119	3
+Peroxiredoxin, C-terminal [IPR019479]	0.3518821603927978	0.1571999382724752	0.8750872769477853	1.0	0.9915431271162686	4	Q13162,P30041,P32119	3
+Tudor domain [IPR002999]	0.3387134146065856	0.1536245198556601	0.877905802391979	1.0	0.9915431271162686	8	Q14739	1
+NADP-dependent oxidoreductase domain [IPR023210]	0.4258930493140113	0.1530959724499129	0.8783225919566704	1.0	0.9915431271162686	3	P15121	1
+FERM, C-terminal PH-like domain [IPR018980]	0.3372087442961915	0.1499776551730832	0.8807822444338003	1.0	0.9915431271162686	5	P35241,P15311	2
+FERM, N-terminal [IPR018979]	0.3372087442961915	0.1499776551730832	0.8807822444338003	1.0	0.9915431271162686	5	P35241,P15311	2
+OBG-type guanine nucleotide-binding (G) domain [IPR031167]	0.3430762640197979	0.1424262306036393	0.8867433445556612	1.0	0.9915431271162686	4	P55039	1
+Ran binding domain [IPR000156]	0.3425823624188252	0.1416327754628843	0.8873700768187156	1.0	0.9915431271162686	4	P43487	1
+DNA-directed RNA polymerase, subunit 2, hybrid-binding domain [IPR007120]	0.555192150449723	0.1377990743308771	0.8903992159578815	1.0	0.9915431271162686	2	Q9H9Y6	1
+RNA polymerase Rpb2, domain 7 [IPR007641]	0.555192150449723	0.1377990743308771	0.8903992159578815	1.0	0.9915431271162686	2	Q9H9Y6	1
+RNA polymerase, beta subunit, protrusion [IPR007644]	0.555192150449723	0.1377990743308771	0.8903992159578815	1.0	0.9915431271162686	2	Q9H9Y6	1
+RNA polymerase Rpb2, domain 2 [IPR007642]	0.555192150449723	0.1377990743308771	0.8903992159578815	1.0	0.9915431271162686	2	Q9H9Y6	1
+RNA polymerase Rpb2, domain 3 [IPR007645]	0.555192150449723	0.1377990743308771	0.8903992159578815	1.0	0.9915431271162686	2	Q9H9Y6	1
+La-type HTH domain [IPR006630]	0.3291035611952528	0.1347567035823746	0.8928042390381914	1.0	0.9915431271162686	5	Q4G0J3,Q71RC2,Q6PKG0,P05455	4
+Exportin-1/Importin-beta-like [IPR013598]	0.337561374795418	0.1337775767896251	0.8935784589231361	1.0	0.9915431271162686	4	Q9Y5L0,O43592,Q9HAV4	3
+Phox homology [IPR001683]	0.3153489407867504	0.1050550374017133	0.9163321367608486	1.0	0.9915431271162686	8	Q13596,Q9Y5X3,Q9Y2I1,O60749	4
+N-acetylgalactosaminyltransferase [IPR045885]	0.5306623058054064	0.1037359981217703	0.9173788583849444	1.0	0.9915431271162686	2	Q10471	1
+Synaptic functional regulator FMRP, KH0 domain [IPR040472]	0.3893660531697297	0.0973605073784353	0.9224401062306612	1.0	0.9915431271162686	3	P51116,Q06787	2
+Fragile X-related 1 protein, C-terminal core [IPR022034]	0.3893660531697297	0.0973605073784353	0.9224401062306612	1.0	0.9915431271162686	3	P51116,Q06787	2
+Fxr1, tudor domain [IPR041560]	0.3893660531697297	0.0973605073784353	0.9224401062306612	1.0	0.9915431271162686	3	P51116,Q06787	2
+Agenet-like domain [IPR008395]	0.3893660531697297	0.0973605073784353	0.9224401062306612	1.0	0.9915431271162686	3	P51116,Q06787	2
+RNA-binding S4 domain [IPR002942]	0.5167620605069605	0.0872773250839242	0.9304510771944708	1.0	0.9915431271162686	2	P62701	1
+OCRE domain [IPR041591]	0.5155355682747447	0.0859210482689732	0.931529179284541	1.0	0.9915431271162686	2	P52756	1
+PABP, RNA recognition motif 2 [IPR045305]	0.5049059689288743	0.0748019642072021	0.9403722789869542	1.0	0.9915431271162686	2	P11940	1
+Ku70/Ku80, N-terminal alpha/beta [IPR005161]	0.5008176614881548	0.0708231600219551	0.9435384990738858	1.0	0.9915431271162686	2	P12956	1
+Ku70/Ku80 beta-barrel domain [IPR006164]	0.5008176614881548	0.0708231600219551	0.9435384990738858	1.0	0.9915431271162686	2	P12956	1
+Ku70/Ku80 C-terminal arm [IPR005160]	0.5008176614881548	0.0708231600219551	0.9435384990738858	1.0	0.9915431271162686	2	P12956	1
+Oxoglutarate/iron-dependent dioxygenase [IPR005123]	0.2828267820011578	0.0627783445550265	0.9499430103893234	1.0	0.9915431271162686	7	Q8N543,O15460,P13674	3
+Prolyl 4-hydroxylase, alpha subunit [IPR006620]	0.2828267820011578	0.0627783445550265	0.9499430103893234	1.0	0.9915431271162686	7	Q8N543,O15460,P13674	3
+Gelsolin-like domain [IPR007123]	0.2625307066823121	0.0585587961796179	0.9533035302175435	1.0	0.9915431271162686	4	Q15436	1
+Chromo domain [IPR023780]	0.2694512694512655	0.0544022161584307	0.9566147132324327	1.0	0.9915431271162686	6	P83916,Q99549,Q13185,O14646,Q14839	5
+Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain [IPR020059]	0.4799672935404859	0.0529821578341645	0.9577461237300308	1.0	0.9915431271162686	2	P47897	1
+Importin-beta, N-terminal domain [IPR001494]	0.3120561001505811	0.050405124786169	0.95979955259082	1.0	0.9915431271162686	13	O95373,Q9UIA9,P55060,O15397,O00410,Q96P70,Q92973,Q8TEX9	8
+Actin-depolymerising factor homology domain [IPR002108]	0.2654410586188069	0.0496956912710381	0.9603648900865144	1.0	0.9915431271162686	6	Q9Y281	1
+BZW1/2, W2 domain [IPR043510]	0.4721995094031154	0.047328947066038	0.9622510575052275	1.0	0.9915431271162686	2	Q9Y6E2	1
+Vacuolar protein sorting-associated protein 4, MIT domain [IPR045253]	0.4677023712183258	0.0442876902294446	0.9646750838217965	1.0	0.9915431271162686	2	O75351	1
+Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]	0.4615699100572483	0.0404038578264497	0.9677711546616824	1.0	0.9917260292699616	2	O60506	1
+Nuclear transport factor 2 domain [IPR002075]	0.3259713701431431	0.0384606999435271	0.9693203651865074	1.0	0.9917260292699616	3	Q9UN86,Q13283	2
+Nuclear transport factor 2, eukaryote [IPR018222]	0.3259713701431431	0.0384606999435271	0.9693203651865074	1.0	0.9917260292699616	3	Q9UN86,Q13283	2
+PurM-like, N-terminal domain [IPR016188]	0.4578904333605971	0.0382147725707862	0.9695164426912466	1.0	0.9917260292699616	2	P22102	1
+JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]	0.2523798665465489	0.0290426340539842	0.9768305878641346	1.0	0.9960238153231634	7	P51665	1
+WW domain [IPR001202]	0.2703381107943826	0.0243229320129543	0.980595021439396	1.0	0.9965359530466318	10	Q13526	1
+CUB domain [IPR000859]	0.4178250204415457	0.0204125930238365	0.9837142381636448	1.0	0.9986847506457668	2	O14786	1
+UAS [IPR006577]	0.4157808667211888	0.0197629032209052	0.984232511040932	1.0	0.9986847506457668	2	Q9UNN5	1
+Hotdog acyl-CoA thioesterase (ACOT)-type domain [IPR033120]	0.4145543744889729	0.0193834721820791	0.9845351952207126	1.0	0.9986847506457668	2	O00154	1
+La protein, xRRM domain [IPR014886]	0.3953393295175903	0.014373316044287	0.9885321479035754	1.0	1.0	2	P05455	1
+CLASP N-terminal domain [IPR024395]	0.3945216680294428	0.0141958957015323	0.9886736944136292	1.0	1.0	2	Q7Z460	1
+CARG-binding factor, N-terminal [IPR012956]	0.3863450531480036	0.0125639582802198	0.9899756753947	1.0	1.0	2	Q99729	1
+Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394]	0.2562487882796997	0.0123270486049704	0.9901646873277958	1.0	1.0	10	Q96K76	1
+Ubiquitin specific protease domain [IPR028889]	0.2562487882796997	0.0123270486049704	0.9901646873277958	1.0	1.0	10	Q96K76	1
+Coatomer, gamma subunit, appendage, Ig-like subdomain [IPR013040]	0.3626328699918307	0.0090907083947684	0.9927467640276112	1.0	1.0	2	Q9Y678	1
+Coatomer subunit gamma, C-terminal [IPR032154]	0.3626328699918307	0.0090907083947684	0.9927467640276112	1.0	1.0	2	Q9Y678	1
+ZU5 domain [IPR000906]	0.340964840556018	0.0071634885528684	0.994284411965328	1.0	1.0	2	Q12955	1
+Death domain [IPR000488]	0.2972199509403193	0.005410734961573	0.9956828791762844	1.0	1.0	2	Q12955	1
+Damage-control phosphatase ARMT1-like, metal-binding domain [IPR002791]	0.2943581357318158	0.0053563296291666	0.9957262877219846	1.0	1.0	2	Q9H993	1
+Sec24-like, trunk domain [IPR041742]	0.2910874897792403	0.0052999877138362	0.9957712414282408	1.0	1.0	2	O95486	1
+SNF2, N-terminal [IPR000330]	0.2419523250650721	0.0028649439763785	0.9977141085607456	1.0	1.0	10	Q9H4L7,Q2NKX8	2

interpro_family/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Proteasome B-type subunit [IPR023333]"}

interpro_family/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Proteasome B-type subunit [IPR023333]", "1": "Proteasome, subunit alpha/beta [IPR001353]", "2": "26S proteasome regulatory subunit P45-like [IPR005937]", "3": "Chaperone tailless complex polypeptide 1 (TCP-1) [IPR017998]"}

interpro_family/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:166af9938728ee16b21fbf31c96e7d8cd6532efb8a6b98ba6e29cc532429ee96
+size 89229

interpro_family/df_merge.tsv

@@ -0,0 +1,2 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Proteasome B-type subunit [IPR023333]	5	7	2.4120442837340867	0.0158633546503126	3.699029126213592	6.970873786407767	1.6670727234653664	0.1509307531330224	1.4503762582219135	0.1681602725795027	0.9611878160538336	0.233503072382129	1.0	0.0007972103198291	6.521763918376504e-05	7.440167567491937e-07	8.150277876805989e-07

interpro_family/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2448,
+    "annotations_size": 1938,
+    "title": "Average number of proteins per term",
+    "value": 1.2657378740970073
+}

interpro_family/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_family/fragment/C327/C327_val_log2fc"}