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interpro_active_site/advanced/idx2term.json

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+{}

interpro_active_site/basic/idx2term.json

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+{}

interpro_active_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:f2ad90c94f1d4d713477164b878d0c3985b7ad5f608c7f2f06e5d001d05236b9
+size 55473

interpro_active_site/df_merge.tsv

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+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_active_site/metrics.json

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+{
+    "type_of_task": "ranksum",
+    "signature_size": 2448,
+    "annotations_size": 49,
+    "title": "Average number of proteins per term",
+    "value": 2.3469387755102042
+}

interpro_active_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C328/C328_val_log2fc"}

interpro_active_site/result.tsv

@@ -0,0 +1,6 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Ubiquitin-conjugating enzyme, active site [IPR023313]	0.7183963834652025	1.5314454540469449	0.1256593375417036	0.9986121160906068	0.4736390415033445	5	P61088,Q16763,P68036	3
+Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]	0.8691741618969744	0.810970677982916	0.4173825097691521	0.99999999999681	0.8057562858407719	2	P18669	1
+ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]	0.5440902090085837	0.6156401746382462	0.5381320299212893	1.0	0.8057562858407719	4	P21281	1
+Serine carboxypeptidase, serine active site [IPR018202]	0.658964977982345	0.5359628729619855	0.5919842100054651	1.0	0.8057562858407719	3	Q9HB40	1
+Cysteine peptidase, cysteine active site [IPR000169]	0.2478527607361869	0.0105813747049037	0.9915574420370388	1.0	1.0	3	P07384,Q13867	2

interpro_active_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenylosuccinate synthase,  active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, cysteine active site [IPR000169]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADSS", "APEH", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "AURKA", "BLMH", "BUB1", "CAPN1", "CAPN2", "CDK1", "CDK12", "CDK4", "CDK5", "CHEK2", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "FASN", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLUD1", "GSK3B", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "LDHA", "LDHB", "LONP1", "MAP2K1", "MAPK1", "MAPK3", "MDH1", "MDH2", "NEK9", "NME1", "NME2", "OXCT1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKN2", "PLK1", "PREP", "PRKACA", "PRPF4B", "PTK7", "PTPN1", "PTPN11", "RNASET2", "ROCK1", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TPI1", "TPP2", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UMPS", "VRK1", "VRK2"], "leading_proteins": ["ATP6V1B2", "BLMH", "CAPN1", "PGAM1", "SCPEP1", "UBE2L3", "UBE2N", "UBE2S"]}

interpro_binding_site/advanced/idx2term.json

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+{}

interpro_binding_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "EF-Hand 1, calcium-binding site [IPR018247]"}

interpro_binding_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:0a25873b915840a84f2a31b90fe9ebad427dd008c0ec575b595d1588a02dfd82
+size 55174

interpro_binding_site/df_merge.tsv

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+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_binding_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2448,
+    "annotations_size": 30,
+    "title": "Average number of proteins per term",
+    "value": 3.8
+}

interpro_binding_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C328/C328_val_log2fc"}

interpro_binding_site/result.tsv

@@ -0,0 +1,4 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]	0.8708094848732645	0.8164684451217675	0.4142322639283753	0.9999998924121036	0.778143715653304	2	P34896	1
+EF-Hand 1, calcium-binding site [IPR018247]	0.4003238631446468	0.7705931789221632	0.4409481055368722	0.9999999734805992	0.778143715653304	31	Q02818,O75340,Q15293,O43852,Q96AY3,P80303,Q14257,P0DP25	8
+PPM-type phosphatase, divalent cation binding [IPR000222]	0.5429272281275647	0.067651489579268	0.9460630664939732	1.0	0.9460630664939732	2	Q9H0C8	1

interpro_binding_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO2", "ACTN1", "ACTN4", "ADSS", "APEX1", "ARG2", "AURKA", "BPNT1", "BUB1", "CALM3", "CALU", "CAPN1", "CAPN2", "CDK1", "CDK12", "CDK4", "CDK5", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPS15", "FKBP10", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQGAP1", "IQGAP2", "LETM1", "MACF1", "MAP2K1", "MAPK1", "MAPK14", "MAPK3", "MCCC1", "METAP2", "MYH10", "MYH9", "MYO1B", "MYO1C", "MYO1D", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXCT1", "PA2G4", "PAK2", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKN2", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "PPM1G", "PRKACA", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "RPS6KA1", "RPS6KA3", "S100A11", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "TKT", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4B", "TUBB6", "UBE3C", "UQCRC2", "VRK1"], "leading_proteins": ["CALM3", "CALU", "FKBP10", "ILKAP", "NUCB1", "NUCB2", "PDCD6", "RCN1", "RCN2", "SHMT1"]}

interpro_conserved_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_conserved_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "14-3-3 protein, conserved site [IPR023409]", "1": "Zinc finger, RING-type, conserved site [IPR017907]", "2": "Chaperonin TCP-1, conserved site [IPR002194]"}

interpro_conserved_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:d9a47b1894a57886bae064745d45723d37344c1557d6c354053a0bb337300851
+size 63170

interpro_conserved_site/df_merge.tsv

@@ -0,0 +1,3 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Proteasome beta-type subunit, conserved site [IPR016050]	4	8	2.215433517149507	0.0267303229024316	3.7135922330097086	7.970873786407767	1.4913184573846054	0.1902243906475925	1.515457478026574	0.1681602725795027	1.0170822776023185	0.2455850375425174	0.0146210495030978	0.0451714964804377	1.4230123382762213e-06	1.6869029898987774e-06	6.091205049008097e-08
+Intermediate filament protein, conserved site [IPR018039]	4	5	2.0662129694351736	0.0388083747724152	4.060679611650485	7.546116504854369	0.7869831563787604	0.2926647109331939	1.9153715257926656	0.8924219614624045	1.3691577499316503	0.3120813432784052	1.0	1.0	0.155187298262897	0.0673816698512089	0.0012892425867137

interpro_conserved_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2448,
+    "annotations_size": 259,
+    "title": "Average number of proteins per term",
+    "value": 2.444015444015444
+}

interpro_conserved_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C328/C328_val_log2fc"}

interpro_conserved_site/result.tsv

@@ -0,0 +1,31 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Proteasome beta-type subunit, conserved site [IPR016050]	0.7975393286630945	2.215433517149507	0.0267303229024316	0.9991038164984558	0.4563783924194378	8	P28070,P20618,P49721,P28072	4
+Intermediate filament protein, conserved site [IPR018039]	0.8473188702415064	2.0662129694351736	0.0388083747724152	0.9999646992161502	0.4563783924194378	5	P02545,P07197,Q03252,P08670	4
+14-3-3 protein, conserved site [IPR023409]	0.7420147420147468	1.8790886776823212	0.0602323858675097	0.9999998971266484	0.4563783924194378	6	P61981,P62258,P63104,P27348,Q04917	5
+Annexin repeat, conserved site [IPR018252]	0.8012332790895116	1.8778245677563543	0.0604051682178066	0.99999990191098	0.4563783924194378	5	P04083,P08133	2
+FERM conserved site [IPR019747]	0.6912696411703428	1.6573421682838598	0.0974503164303635	0.999999999997069	0.4820768682589054	6	P26038,P35241	2
+Chromo domain, conserved site [IPR023779]	0.6536234787156303	1.2559524552222547	0.2091332085370996	1.0	0.7296699216025141	5	P83916,Q13185,O14646	3
+Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]	0.9452166802943583	1.0739675121212766	0.2828372426731964	1.0	0.8308400122222561	2	P05067	1
+Amyloidogenic glycoprotein,  copper-binding domain conserved site [IPR019744]	0.9452166802943583	1.0739675121212766	0.2828372426731964	1.0	0.8308400122222561	2	P05067	1
+Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]	0.9452166802943583	1.0739675121212766	0.2828372426731964	1.0	0.8308400122222561	2	P05067	1
+Mini-chromosome maintenance, conserved site [IPR018525]	0.5477458779072573	1.0151810416815834	0.3100195359656554	1.0	0.8829101837531593	6	P33993,Q14566	2
+Tetraspanin, conserved site [IPR018503]	0.8581357318070346	0.7740940509477195	0.4388751752595838	1.0	0.986775274660598	2	O43657	1
+Heat shock protein Hsp90, conserved site [IPR019805]	0.7198364008179952	0.7390451677515879	0.4598795707186671	1.0	0.986775274660598	3	P07900,P08238	2
+Zinc finger, RING-type, conserved site [IPR017907]	0.4369324034511569	0.627735859972079	0.5301769897070183	1.0	0.986775274660598	11	Q99590,Q96T88,P38398,Q14258,P19474,Q5VTR2	6
+Macrophage migration inhibitory factor, conserved site [IPR019829]	0.7882256745707328	0.5523365821188289	0.5807177714217535	1.0	0.986775274660598	2	P14174	1
+Adenylate kinase, conserved site [IPR033690]	0.6135764980951439	0.3998411579744075	0.6892735140457389	1.0	0.987728740564816	3	P30085	1
+Dynamin, GTPase region, conserved site [IPR019762]	0.7207686017988595	0.3654368630930337	0.7147853283666095	1.0	0.987728740564816	2	P50570	1
+ABC transporter-like, conserved site [IPR017871]	0.3885988200535173	0.3640809993437741	0.7157975248915012	1.0	0.987728740564816	7	P08183	1
+Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]	0.6917416189697518	0.2959570214044002	0.7672629037310046	1.0	0.987728740564816	2	P24534	1
+Cyclic nucleotide-binding, conserved site [IPR018488]	0.6668029435813634	0.2423977156992507	0.8084720042170312	1.0	0.987728740564816	2	P10644	1
+Phosphorylase pyridoxal-phosphate attachment site [IPR035090]	0.654129190515133	0.2174829511449718	0.8278319920614685	1.0	0.987728740564816	2	P11216	1
+DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]	0.6095666394112915	0.142711016123322	0.8865184161684918	1.0	0.987728740564816	2	P19387	1
+Thioredoxin, conserved site [IPR017937]	0.3052658724067765	0.1153962011033564	0.9081310899290418	1.0	0.9879153960630396	9	O95881,P07237,O43396	3
+Mrp, conserved site [IPR000808]	0.5838103025347591	0.1086522540283047	0.9134783133277138	1.0	0.9879153960630396	2	Q8TB37	1
+Ubiquitin interacting motif [IPR003903]	0.5057236304170182	0.0426450041448609	0.9659845199812528	1.0	1.0	2	P55036	1
+Alpha-D-phosphohexomutase, conserved site [IPR016066]	0.4031524459472901	0.0418849169442348	0.9665904403812158	1.0	1.0	3	O95394	1
+GTP1/OBG, conserved site [IPR006074]	0.4582992641046728	0.0239869711271811	0.9808630012525468	1.0	1.0	2	P55039	1
+Ubiquitin-activating enzyme E1, conserved site [IPR018074]	0.4341782502044253	0.0186221381901928	0.985142542175389	1.0	1.0	2	Q9UBT2	1
+Chaperonin TCP-1, conserved site [IPR002194]	0.2454918032786942	0.0183572667491739	0.9853538428864792	1.0	1.0	8	P49368,Q99832,P50991,P78371,P48643,P40227,P17987	7
+Ribosomal protein L24/L26, conserved site [IPR005825]	0.349959116925602	0.0114968292837738	0.9908270594921564	1.0	1.0	2	Q96A35	1
+Histidine triad, conserved site [IPR019808]	0.3450531479967395	0.0113767113079751	0.990922893502728	1.0	1.0	2	Q96C86	1

interpro_conserved_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Amyloidogenic glycoprotein,  copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific,  conserved site [IPR031303]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P,  conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor, T-box, conserved site [IPR018186]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR1A", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AK1", "AK2", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "APEX1", "APLP2", "APP", "ATAD1", "ATP5C1", "ATP5O", "BAG6", "BAX", "BAZ1A", "BAZ1B", "BCAT2", "BDH2", "BLM", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD2", "BRD4", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CBR1", "CBX1", "CBX3", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDH2", "CDKAL1", "CHAF1B", "CHD1", "CHD4", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1C", "CPOX", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX40", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJC1", "DNAJC11", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DRG1", "DRG2", "DSC3", "DSG2", "DST", "DTYMK", "DYNLL1", "EARS2", "ECH1", "ECHS1", "ECI1", "ECI2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "ENO1", "EPB41", "EPB41L2", "EPDR1", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXC1", "FUCA1", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLO1", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GRWD1", "GSPT1", "GTF3C2", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB3", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IDH1", "IDH2", "IDH3A", "IDH3B", "ILVBL", "IMPDH2", "IQGAP1", "IQGAP2", "IVD", "KDM2A", "KDSR", "KIF11", "KIF18A", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MAPK3", "MARS", "MAT2A", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME2", "MGA", "MGST2", "MIF", "MPHOSPH8", "MPI", "MPP6", "MPST", "MRPL24", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFV1", "NEFM", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD2", "NSF", "NUBP2", "NUBPL", "NUDT1", "NUDT5", "NUP153", "NUP37", "NVL", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF14", "PHF3", "PHF8", "PHGDH", "PHIP", "PI4KB", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PNP", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "RACK1", "RAE1", "RANBP2", "RARS", "RBBP7", "RCL1", "RDH13", "RDX", "RIDA", "RNF114", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "S100A10", "S100A11", "SART1", "SBDS", "SCAF11", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC27A4", "SLIT2", "SMARCA4", "SMU1", "SNRNP40", "SPATA5", "SPATA5L1", "SPTBN1", "SRCAP", "SRM", "STMN1", "STX12", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "TBL3", "TCP1", "TK1", "TLN1", "TMX1", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM21", "TRIM25", "TRIM27", "TRIM28", "TRIM33", "TRIP13", "TSFM", "TSPAN3", "TSPAN6", "TUBB", "TUBB2A", "TUBB2B", "TUBB4B", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UHRF1", "USP10", "USP14", "USP15", "USP33", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZMYND8"], "leading_proteins": ["ABCB1", "ANXA1", "ANXA6", "APP", "BRCA1", "CBX1", "CBX3", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CHD1", "CMPK1", "DCPS", "DNM2", "DRG2", "EEF1B2", "HSP90AA1", "HSP90AB1", "LMNA", "LMNB2", "MCM6", "MCM7", "MIF", "MRPL24", "MSN", "NEFM", "NUBPL", "P4HB", "PGM3", "POLR2C", "PRKAR1A", "PSMB1", "PSMB2", "PSMB4", "PSMB6", "PSMD4", "PYGB", "RDX", "RNF20", "SCAF11", "TCP1", "TRIM21", "TRIM25", "TSPAN6", "TXNDC12", "TXNL1", "UBA2", "UHRF1", "VIM", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ"]}

interpro_domain/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Proteasome component (PCI) domain [IPR000717]"}

interpro_domain/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Proteasome component (PCI) domain [IPR000717]", "1": "K Homology domain [IPR004087]", "2": "14-3-3 domain [IPR023410]", "3": "K Homology domain, type 1 [IPR004088]", "4": "Small GTP-binding protein domain [IPR005225]", "5": "Ubiquitin-like domain [IPR000626]", "6": "Thioredoxin domain [IPR013766]", "7": "RNA recognition motif domain [IPR000504]", "8": "Zinc finger C2H2-type [IPR013087]", "9": "EF-hand domain [IPR002048]", "10": "Phosphoribosyltransferase domain [IPR000836]", "11": "Matrin/U1-C-like, C2H2-type zinc finger [IPR003604]"}

interpro_domain/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:12cb16b7c6c21214b0fe409056bcc700aabf7efbc50ec73d7d8e6f188b00f4de
+size 128188

interpro_domain/df_merge.tsv

@@ -0,0 +1,6 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]	4	7	2.291035376386754	0.0219613676911112	3.1262135922330097	10.111650485436892	0.9686720267359892	0.3700536707457866	1.7316562118191232	1.203619216216406	0.9607394322697528	0.3108814801432357	1.0	1.0	0.0062673893229953	8.123400840332367e-06	0.0002366253635482
+Zinc finger, RanBP2-type [IPR001876]	3	8	2.200913692138255	0.0277421344330057	3.2742718446601944	8.616504854368932	0.6239078002715212	0.4100405386528319	1.463145369641179	0.7330740021954685	1.0299872364022182	0.3121093098016552	1.0	0.0041305095198808	0.0160779799666689	0.0013685442029889	0.0027167172984866
+Proteasome component (PCI) domain [IPR000717]	8	17	2.093736322258237	0.0362834754091847	6.577669902912621	18.740291262135923	0.0656253515457994	0.631967867263698	3.806137915628319	1.385790550244499	0.8221014102906427	0.3084914974953499	1.0	1.0	0.0191384435432636	0.0166512768388831	7.054620871649191e-06
+Intermediate filament, rod domain [IPR039008]	4	5	2.0662129694351736	0.0388083747724152	4.060679611650485	7.546116504854369	0.7869831563787604	0.2926647109331939	1.9153715257926656	0.8924219614624045	1.3691577499316503	0.3120813432784052	1.0	1.0	0.186294400244323	0.0956821003940122	0.0033786658518103
+Ubiquitin-associated domain [IPR015940]	3	9	2.050154342092786	0.040349371869411	4.757281553398058	13.609223300970871	0.1518609635645758	0.6189618326330407	2.6965134605741876	2.7315510687883564	0.8294496783626069	0.3065476877023595	1.0	1.0	0.3128231991631071	0.0146876851094623	0.0416531657976321

interpro_domain/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2448,
+    "annotations_size": 2188,
+    "title": "Average number of proteins per term",
+    "value": 2.053930530164534
+}

interpro_domain/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C328/C328_val_log2fc"}

interpro_domain/result.tsv

@@ -0,0 +1,195 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]	0.8274462009292854	2.291035376386754	0.0219613676911112	1.0	0.5472754222616835	7	P26885,Q02790,O00170,Q96AY3	4
+Zinc finger, RanBP2-type [IPR001876]	0.794220818577822	2.200913692138255	0.0277421344330057	1.0	0.5472754222616835	8	P35637,Q01844,Q92804	3
+Proteasome component (PCI) domain [IPR000717]	0.6380752419653749	2.0937363222582372	0.0362834754091847	1.0	0.5472754222616835	17	Q7L2H7,O00231,Q99627,O43242,P60228,Q9BT78,Q9UBW8,Q9Y262	8
+Intermediate filament, rod domain [IPR039008]	0.8473188702415064	2.0662129694351736	0.0388083747724152	1.0	0.5472754222616835	5	P02545,P07197,Q03252,P08670	4
+Ubiquitin-associated domain [IPR015940]	0.7482093746369312	2.050154342092786	0.040349371869411	1.0	0.5472754222616835	9	Q04323,Q14157,Q9NRR5	3
+K Homology domain [IPR004087]	0.5448123429826761	1.949880722118971	0.0511903373572324	1.0	0.5472754222616835	22	P61978,Q06787,Q96AE4,Q96PU8,Q15637,Q9Y6M1,Q07666,Q92945	8
+RNA recognition motif domain, eukaryote [IPR003954]	0.7002182939757978	1.9421643004688096	0.0521172133400911	1.0	0.5472754222616835	11	Q14011,P38159,Q9UHX1	3
+W2 domain [IPR003307]	0.7433517873061682	1.9278141722873896	0.0538782442731424	1.0	0.5472754222616835	7	P55010	1
+14-3-3 domain [IPR023410]	0.7420147420147468	1.8790886776823212	0.0602323858675097	1.0	0.5482963458262469	6	P61981,P62258,P63104,P27348,Q04917	5
+K Homology domain, type 1 [IPR004088]	0.5220140200094348	1.7936526579341048	0.0728686260730324	1.0	0.5530189590400723	22	P61978,Q06787,Q96AE4,Q96PU8,Q15637,Q9Y6M1,Q92945	7
+Proteasome alpha-subunit, N-terminal domain [IPR000426]	0.6973704028314551	1.7233647493619602	0.0848225853594242	1.0	0.5657503082798508	7	P60900,P25789,P25786	3
+Cold-shock protein, DNA-binding [IPR002059]	0.8180563473536662	1.703012719966527	0.0885656880092877	1.0	0.5657503082798508	4	P16989	1
+Cold-shock (CSD) domain [IPR019844]	0.8180563473536662	1.703012719966527	0.0885656880092877	1.0	0.5657503082798508	4	P16989	1
+Cold shock domain [IPR011129]	0.8180563473536662	1.703012719966527	0.0885656880092877	1.0	0.5657503082798508	4	P16989	1
+FERM domain [IPR000299]	0.6912696411703428	1.6573421682838598	0.0974503164303635	1.0	0.5894770300932398	6	P26038,P35241	2
+U-box domain [IPR003613]	0.7182290638176111	1.530737523635774	0.1258342759398534	1.0	0.6346449022972037	5	P19474	1
+LEM domain [IPR003887]	0.7165893929763987	1.5237986563183996	0.1275590153315033	1.0	0.6374763020234695	5	Q86XL3,Q9Y2U8	2
+FERM, C-terminal PH-like domain [IPR018980]	0.7076086083894844	1.4857496435322357	0.137345354237109	1.0	0.6472575113441744	5	P26038,P35241	2
+FERM, N-terminal [IPR018979]	0.7076086083894844	1.4857496435322357	0.137345354237109	1.0	0.6472575113441744	5	P26038,P35241	2
+Dynamin, N-terminal [IPR045063]	0.6201424605637685	1.3403925037073692	0.1801177715603901	1.0	0.7062682512081246	6	Q9H4M9,Q9H223,Q8IWA4,P50570	4
+Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]	0.6201424605637685	1.3403925037073692	0.1801177715603901	1.0	0.7062682512081246	6	Q9H4M9,Q9H223,Q8IWA4,P50570	4
+MRH domain [IPR044865]	0.8723926380368084	1.299622730622426	0.1937303051260974	1.0	0.7296298540294512	3	P11717,P20645	2
+Peroxiredoxin, C-terminal [IPR019479]	0.7177530967755827	1.298606886549159	0.1940788734209966	1.0	0.7296298540294512	4	P30041	1
+Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant [IPR000866]	0.7177530967755827	1.298606886549159	0.1940788734209966	1.0	0.7296298540294512	4	P30041	1
+Immunoglobulin subtype [IPR003599]	0.6073375583856786	1.2828517252300211	0.1995440283968206	1.0	0.7415388148015044	6	Q92859	1
+Immunoglobulin subtype 2 [IPR003598]	0.6073375583856784	1.282851725230021	0.1995440283968208	1.0	0.7415388148015044	6	Q92859	1
+Chromo domain [IPR023780]	0.6062286850544909	1.2778655816099669	0.2012968256781981	1.0	0.7415388148015044	6	P83916,Q13185,O14646	3
+Heat shock chaperonin-binding [IPR006636]	0.8638036809815884	1.2672292523283943	0.2050733290015882	1.0	0.7465897568310733	3	P54727,Q9NRR5	2
+Aminopeptidase N-like , N-terminal domain [IPR045357]	0.7070856718430221	1.255359394962086	0.2093483226763948	1.0	0.7493705624685525	4	P55786	1
+Peptidase M1, membrane alanine aminopeptidase [IPR014782]	0.7070856718430221	1.255359394962086	0.2093483226763948	1.0	0.7493705624685525	4	P55786	1
+UBX domain [IPR001012]	0.6527150266861024	1.2520777752423378	0.2105415251850562	1.0	0.7493705624685525	5	Q9UNN5,Q04323	2
+Lamin tail domain [IPR001322]	0.8466257668711689	1.20255766985949	0.229147536688171	1.0	0.7688541101230367	3	Q03252,P02545	2
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	0.6372581110495747	1.1861677152671828	0.23555607314268	1.0	0.7694651263438335	5	O15173,O43169	2
+ERAP1-like C-terminal domain [IPR024571]	0.9685200327064596	1.1567417138138325	0.2473779015883137	1.0	0.7894650992563298	2	P55786	1
+ERM family, FERM domain C-lobe [IPR041789]	0.831083844580774	1.1442332823665993	0.2525269037873221	1.0	0.7979668632184911	3	P26038,P35241	2
+RBM3/CIRBP, RNA recognition motif [IPR034278]	0.9644317252657406	1.1421700199966145	0.2533833550198068	1.0	0.7979668632184911	2	Q14011	1
+Zinc finger, CCHC-type [IPR001878]	0.5732490014078642	1.1295318562072292	0.2586735389246872	1.0	0.7979668632184911	6	Q16629,Q7Z6E9	2
+Thioredoxin-like fold [IPR012336]	0.9550286181520852	1.1087322131618849	0.2675457209582825	1.0	0.8119140602728464	2	Q8NBF2	1
+S100/CaBP-9k-type, calcium binding, subdomain [IPR013787]	0.8166078058431384	1.090129343339594	0.275656172140974	1.0	0.8248350059088475	3	Q99584	1
+Amyloidogenic glycoprotein, E2 domain [IPR024329]	0.9452166802943583	1.0739675121212766	0.2828372426731964	1.0	0.8315646442019078	2	P05067	1
+Amyloidogenic glycoprotein, copper-binding [IPR011178]	0.9452166802943583	1.0739675121212766	0.2828372426731964	1.0	0.8315646442019078	2	P05067	1
+Amyloidogenic glycoprotein, extracellular [IPR008154]	0.9452166802943583	1.0739675121212766	0.2828372426731964	1.0	0.8315646442019078	2	P05067	1
+Beta-amyloid precursor protein C-terminal [IPR019543]	0.9452166802943583	1.0739675121212766	0.2828372426731964	1.0	0.8315646442019078	2	P05067	1
+Amyloidogenic glycoprotein, heparin-binding [IPR015849]	0.9452166802943583	1.0739675121212766	0.2828372426731964	1.0	0.8315646442019078	2	P05067	1
+Pancreatic trypsin inhibitor Kunitz domain [IPR002223]	0.9452166802943583	1.0739675121212766	0.2828372426731964	1.0	0.8315646442019078	2	P05067	1
+Chromo/chromo shadow domain [IPR000953]	0.5471786433057593	1.0654661810655068	0.2866650217594484	1.0	0.8340732282043526	8	Q8TAQ2,Q13185,O14646,P83916	4
+EH domain [IPR000261]	0.6575419780159941	1.0551468602609315	0.2913581632429727	1.0	0.8382401266448699	4	Q9H4M9,Q9H223	2
+NOPS [IPR012975]	0.8049079754601198	1.0465981682189536	0.2952849471168732	1.0	0.8399179184084246	3	P23246,Q8WXF1	2
+Sorting nexin Vps5-like, C-terminal [IPR015404]	0.6518683790517998	1.032362706133406	0.301902235782848	1.0	0.844923319849093	4	Q9Y5X3	1
+MCM N-terminal domain [IPR027925]	0.5477458779072573	1.0151810416815834	0.3100195359656554	1.0	0.8543107615779019	6	P33993,Q14566	2
+MCM domain [IPR001208]	0.5477458779072573	1.0151810416815834	0.3100195359656554	1.0	0.8543107615779019	6	P33993,Q14566	2
+MCM OB domain [IPR033762]	0.5477458779072573	1.0151810416815834	0.3100195359656554	1.0	0.8543107615779019	6	P33993,Q14566	2
+MCM, AAA-lid domain [IPR041562]	0.5477458779072573	1.0151810416815834	0.3100195359656554	1.0	0.8543107615779019	6	P33993,Q14566	2
+Immunoglobulin-like domain [IPR007110]	0.5212955401657012	0.9735071176572212	0.3303013244359234	1.0	0.8603563069830957	9	Q92859	1
+Zinc finger, CHHC-type [IPR012996]	0.7766871165644109	0.9425449698725632	0.3459136988682705	1.0	0.8687041817144272	3	P55795,P31943	2
+Small GTP-binding protein domain [IPR005225]	0.4305617117830669	0.9263822421952348	0.3542473692619268	1.0	0.8768023121550858	34	P40616,P18085,Q969Q5,P61586,P20339	5
+Ubiquitin-like domain [IPR000626]	0.4880871390111043	0.9157753207523194	0.3597847501778426	1.0	0.8800475489172341	12	Q15813,Q96T88,Q5TDH0,Q9NRR5,Q9BZL1,P54727	6
+Thioredoxin domain [IPR013766]	0.4046944283863259	0.8952494066587238	0.3706537790408224	1.0	0.8815113788492602	20	Q6ZRP7,P30041,Q8NBF2,O43396,Q6DKJ4,P32119,P07237,O95881	8
+Guanylate kinase/L-type calcium channel beta subunit [IPR008145]	0.7626465920840031	0.8914057135231767	0.3727115536594958	1.0	0.883543138362687	3	Q9UDY2	1
+Guanylate kinase-like domain [IPR008144]	0.7626465920840031	0.8914057135231767	0.3727115536594958	1.0	0.883543138362687	3	Q9UDY2	1
+MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]	0.7585650409065187	0.8766334493269284	0.3806857648390571	1.0	0.8858543844600286	3	P01889	1
+MHC class I-like antigen recognition-like [IPR011161]	0.7585650409065187	0.8766334493269284	0.3806857648390571	1.0	0.8858543844600286	3	P01889	1
+MHC class I, alpha chain, C-terminal [IPR010579]	0.7585650409065187	0.8766334493269284	0.3806857648390571	1.0	0.8858543844600286	3	P01889	1
+Immunoglobulin C1-set [IPR003597]	0.7585650409065187	0.8766334493269284	0.3806857648390571	1.0	0.8858543844600286	3	P01889	1
+Target SNARE coiled-coil homology domain [IPR000727]	0.5622608367228884	0.8695005650929345	0.3845733991149132	1.0	0.887520996100385	5	O95721,Q86Y82	2
+FERM central domain [IPR019748]	0.5092370903511471	0.864647745015698	0.3872321584639056	1.0	0.887520996100385	7	P26038,P35241	2
+Band 4.1 domain [IPR019749]	0.5092370903511471	0.864647745015698	0.3872321584639056	1.0	0.887520996100385	7	P26038,P35241	2
+EB1, C-terminal [IPR004953]	0.8781684382665588	0.8413126965511102	0.400172779663531	1.0	0.8949728422743334	2	Q15691	1
+EF-hand, Ca insensitive [IPR014837]	0.6027004909983579	0.8374603130009228	0.4023338760368236	1.0	0.8949728422743334	4	P12814,O43707,P35609	3
+Linker histone H1/H5, domain H15 [IPR005818]	0.5068023691107031	0.8338353768990847	0.4043737570573089	1.0	0.8949728422743334	6	P16403,P16402	2
+Fibronectin type II domain [IPR000562]	0.8757154538021268	0.8330126695043918	0.4048375839655174	1.0	0.8949728422743334	2	Q9UBV2	1
+CS domain [IPR007052]	0.5020575502580926	0.8324077614933907	0.4051788225485828	1.0	0.8949728422743334	7	Q9Y266,Q9HB71	2
+Saposin B type domain [IPR008139]	0.8728536385936247	0.8233526864127156	0.4103074605278558	1.0	0.895447155261142	2	P07602	1
+Serine hydroxymethyltransferase-like domain [IPR039429]	0.8708094848732645	0.8164684451217675	0.4142322639283753	1.0	0.8984826103865362	2	P34896	1
+Intermediate filament head, DNA-binding domain [IPR006821]	0.8589533932951793	0.7768112518083455	0.4372701373555663	1.0	0.9206099957593736	2	P08670	1
+Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]	0.8577269010629601	0.7727363418843428	0.439678434201086	1.0	0.9206099957593736	2	O60506	1
+GMP phosphodiesterase, delta subunit [IPR008015]	0.8495502861815252	0.745710159059816	0.4558425209557661	1.0	0.9325358307591004	2	A6NIH7	1
+Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]	0.7202453987729958	0.7404701323993753	0.4590147776922766	1.0	0.9368697141704304	3	O15460,Q32P28	2
+CARG-binding factor, N-terminal [IPR012956]	0.8442354865085888	0.7282787998390369	0.4664429372175922	1.0	0.9441046684848212	2	Q99729	1
+RNA recognition motif domain [IPR000504]	0.5629541179709059	0.6902892142548859	0.4900123292625613	1.0	0.949643026064202	110	Q9Y3B4,P98175,Q13243,Q08170,Q8WXF1,Q8IY67,P84103,Q9GZT3,Q9NTZ6,Q9Y6M1,Q13247,P22626,Q92804,P35637,Q14011,P11940,P31942,Q86U42,Q96PK6,O75494,O15047,Q8WXF0,P23588,Q8IZ69,P07910,O60506,Q96EP5,P31943,Q13148,P52756,P19338,P23246,P38159,Q9UKA9,P62995,Q15056,Q8N684,P98179,P55795,P51991,O43390,Q9UHX1,Q15233,Q01844,Q16629,Q13242,Q99729,Q07955,P09651,O14979,P26368,Q14103,P05455	53
+Zinc finger C2H2-type [IPR013087]	0.4120492464661023	0.6381405321525709	0.5233822039537244	1.0	0.98805889754163	15	Q92785,P52756,Q92766,P98175,O60678	5
+OCRE domain [IPR041591]	0.8143908421913366	0.6326146175601578	0.5269853390557391	1.0	0.99229629088702	2	P98175	1
+Chromo shadow domain [IPR008251]	0.6885096040243457	0.6321012870627314	0.5273206942438198	1.0	0.99229629088702	3	P83916	1
+Chromo domain subgroup [IPR017984]	0.6885096040243457	0.6321012870627314	0.5273206942438198	1.0	0.99229629088702	3	P83916	1
+Domain of unknown function DUF5600 [IPR040990]	0.8103025347506148	0.6198326762976758	0.5353679532098399	1.0	0.9940653749446724	2	Q9H4M9	1
+EH domain-containing protein, N-terminal [IPR031692]	0.8103025347506148	0.6198326762976758	0.5353679532098399	1.0	0.9940653749446724	2	Q9H4M9	1
+ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain [IPR000194]	0.5440902090085837	0.6156401746382462	0.5381320299212893	1.0	0.9940653749446724	4	P21281	1
+ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain [IPR004100]	0.5440902090085837	0.6156401746382462	0.5381320299212893	1.0	0.9940653749446724	4	P21281	1
+Matrin/U1-C, C2H2-type zinc finger [IPR000690]	0.4903388580862781	0.5814854695687469	0.5609133084861275	1.0	0.9940653749446724	5	Q12874,Q15428	2
+Peptidase M3A/M3B catalytic domain [IPR001567]	0.6679836831242931	0.5647560222892741	0.5722397233730785	1.0	0.9940653749446724	3	P52888	1
+Far upstream element-binding protein, C-terminal [IPR015096]	0.7919051512673798	0.5633981722457975	0.5731637815083546	1.0	0.9940653749446724	2	Q96AE4	1
+Serine/arginine-rich splicing factor SRSF4-like, RNA recognition motif 1 [IPR035585]	0.782910874897795	0.5364990873382349	0.5916136665066392	1.0	0.9940653749446724	2	Q13243	1
+Zinc finger, C3HC4 RING-type [IPR018957]	0.6552147239263792	0.5241448748822224	0.6001777786818954	1.0	0.9940653749446724	3	P38398,Q5VTR2	2
+Heat shock protein Hsp90, N-terminal [IPR020575]	0.5160697808561701	0.5162662731535104	0.6056684486581287	1.0	0.9940653749446724	4	P07900,P08238	2
+4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896]	0.6498977505112513	0.507552480982003	0.6117672227653821	1.0	0.9940653749446724	3	P21912,P61221	2
+Proteasome activator PA28, N-terminal domain [IPR003185]	0.6445807770961206	0.4911571664137039	0.6233152915355373	1.0	0.9940653749446724	3	P61289,Q06323	2
+Proteasome activator PA28, C-terminal domain [IPR003186]	0.6445807770961206	0.4911571664137039	0.6233152915355373	1.0	0.9940653749446724	3	P61289,Q06323	2
+Actin-depolymerising factor homology domain [IPR002108]	0.4218996117711385	0.4810639421395092	0.6304710542416772	1.0	0.9940653749446724	6	Q14019	1
+Methyltransferase type 11 [IPR013216]	0.7616516762060566	0.4749110960338519	0.6348503422339169	1.0	0.9940653749446724	2	Q8N6R0	1
+CAP Gly-rich domain [IPR000938]	0.6391409220954385	0.4745941516054275	0.6350762755899682	1.0	0.9940653749446724	3	Q14203	1
+DNA-directed DNA polymerase, family B, exonuclease domain [IPR006133]	0.6366839665774042	0.4671853475678922	0.6403672758713217	1.0	0.9940653749446724	3	P28340	1
+DNA-directed DNA polymerase, family B, multifunctional domain [IPR006134]	0.6366839665774042	0.4671853475678922	0.6403672758713217	1.0	0.9940653749446724	3	P28340	1
+Septin-type guanine nucleotide-binding (G) domain [IPR030379]	0.4572247237003695	0.4597034464945017	0.6457290953646568	1.0	0.9940653749446724	5	Q92599,Q9UHD8,Q16181,Q9NVA2	4
+CUB domain [IPR000859]	0.753475061324615	0.4520249648410203	0.6512509977750891	1.0	0.9940653749446724	2	O14786	1
+Zinc finger C2H2 AKAP95-type [IPR034736]	0.7485690923957535	0.4385204693344086	0.6610090351285525	1.0	0.9940653749446724	2	Q5BKZ1	1
+EF-hand domain [IPR002048]	0.3635430879441206	0.4336165667444177	0.6645669024371408	1.0	0.9940653749446724	37	Q02818,O75340,Q96AY3,P80303,Q14257,P0DP25	6
+Survival motor neuron [IPR010304]	0.746524938675393	0.4329451886807169	0.6650545899626299	1.0	0.9940653749446724	2	O75940	1
+Exportin-2, central domain [IPR013713]	0.6249488752556243	0.432442480031812	0.6654198492351575	1.0	0.9940653749446724	3	P55060,O95373	2
+Beta-adaptin appendage, C-terminal subdomain [IPR015151]	0.6111962424556909	0.3931570982792247	0.6942034541607776	1.0	0.9940653749446724	3	Q10567	1
+GTPase effector domain [IPR020850]	0.7207686017988595	0.3654368630930337	0.7147853283666095	1.0	0.9940653749446724	2	P50570	1
+Dynamin GTPase effector [IPR003130]	0.7207686017988595	0.3654368630930337	0.7147853283666095	1.0	0.9940653749446724	2	P50570	1
+Dynamin stalk domain [IPR000375]	0.7207686017988595	0.3654368630930337	0.7147853283666095	1.0	0.9940653749446724	2	P50570	1
+ABC transporter-like, ATP-binding domain [IPR003439]	0.3885988200535173	0.3640809993437741	0.7157975248915012	1.0	0.9940653749446724	7	P08183	1
+Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547]	0.7199509403107158	0.3633805374267759	0.7163206384620149	1.0	0.9940653749446724	2	O15460	1
+G-protein, beta subunit [IPR001632]	0.7052330335241258	0.3273332914258313	0.7434158151960466	1.0	0.9940653749446724	2	Q9NVX2	1
+B-box-type zinc finger [IPR000315]	0.4147326779736487	0.3192035630509739	0.7495721552632633	1.0	0.9940653749446724	5	P19474	1
+Proteasomal ATPase OB C-terminal domain [IPR032501]	0.4146541137945161	0.3189636017065769	0.7497541138879391	1.0	0.9940653749446724	5	P43686,P17980,P62191,P62195	4
+Reticulon [IPR003388]	0.7007358953393343	0.3166934041198727	0.751476254133286	1.0	0.9940653749446724	2	O95197	1
+Chaperone DnaJ, C-terminal [IPR002939]	0.5762781186094127	0.3011247367005473	0.7633193787806851	1.0	0.9940653749446724	3	P25685,P31689	2
+Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain [IPR014038]	0.6917416189697518	0.2959570214044002	0.7672629037310046	1.0	0.9940653749446724	2	P24534	1
+Elongation factor 1 beta central acidic region, eukaryote [IPR018940]	0.6917416189697518	0.2959570214044002	0.7672629037310046	1.0	0.9940653749446724	2	P24534	1
+PPM-type phosphatase domain [IPR001932]	0.5724914319685261	0.291864820460763	0.7703899821259474	1.0	0.9940653749446724	3	Q15750	1
+Legume-like lectin [IPR005052]	0.6807031888798092	0.2715235551990209	0.7859883855086449	1.0	0.9940653749446724	2	Q12907	1
+FAD-binding domain, PCMH-type [IPR016166]	0.6786590351594496	0.2671242745646467	0.789373478065585	1.0	0.9940653749446724	2	O00116	1
+FAD linked oxidase, N-terminal [IPR006094]	0.6786590351594496	0.2671242745646467	0.789373478065585	1.0	0.9940653749446724	2	O00116	1
+Helicase/UvrB, N-terminal [IPR006935]	0.677023712183162	0.2636334360976987	0.7920623914419727	1.0	0.9940653749446724	2	Q9UPY3	1
+Band 7 domain [IPR001107]	0.3546253908972044	0.2497355336361763	0.8027918768147617	1.0	0.9940653749446724	6	Q99623,O94905,Q9UJZ1	3
+cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain [IPR003117]	0.6668029435813634	0.2423977156992507	0.8084720042170312	1.0	0.9940653749446724	2	P10644	1
+Cyclic nucleotide-binding domain [IPR000595]	0.6668029435813634	0.2423977156992507	0.8084720042170312	1.0	0.9940653749446724	2	P10644	1
+CTP synthase, N-terminal [IPR017456]	0.6663941128372912	0.2415693484203173	0.8091138751440186	1.0	0.9940653749446724	2	Q9NRF8	1
+CTP synthase GATase domain [IPR033828]	0.6663941128372912	0.2415693484203173	0.8091138751440186	1.0	0.9940653749446724	2	Q9NRF8	1
+Myosin tail [IPR002928]	0.6639411283728596	0.2366334724579783	0.8129411503102004	1.0	0.9940653749446724	2	P35580	1
+Glutathione S-transferase, N-terminal [IPR004045]	0.348257904083846	0.231218543654301	0.8171450245419822	1.0	0.9940653749446724	6	P28161	1
+High mobility group box domain [IPR009071]	0.3452539513920394	0.2271000825675546	0.8203459198463479	1.0	0.9940653749446724	9	O15347	1
+NUC153 [IPR012580]	0.6590351594439965	0.2269391147982908	0.8204710862212186	1.0	0.9940653749446724	2	Q9BSC4	1
+Vicinal oxygen chelate (VOC) domain [IPR037523]	0.6565821749795646	0.2221811409906756	0.8241728745429795	1.0	0.9940653749446724	2	Q9HC38	1
+Glucosamine/galactosamine-6-phosphate isomerase [IPR006148]	0.6545380212592048	0.2182618217442294	0.8272251191754731	1.0	0.9940653749446724	2	P46926	1
+DnaJ domain [IPR001623]	0.3329434927982851	0.2066476318214683	0.8362850582460282	1.0	0.9940653749446724	12	O75937,Q8WXX5	2
+Zinc finger, LIM-type [IPR001781]	0.3710660387693508	0.1991848949880137	0.8421181147349934	1.0	0.9940653749446724	5	Q15942	1
+Extended PHD (ePHD) domain [IPR034732]	0.5271176259796948	0.1930097310190766	0.8469513471328873	1.0	0.9940653749446724	3	O94880	1
+Ubiquitin-conjugating enzyme E2 [IPR000608]	0.3303689857460097	0.1810099989622451	0.8563597276231181	1.0	0.9940653749446724	7	P61088,Q16763,P68036	3
+Phosphoribosyltransferase domain [IPR000836]	0.3194103194103194	0.1561500718118799	0.8759147307922655	1.0	0.9940653749446724	6	O60256,P11908,P00492,P11172,P07741	5
+N-acetylgalactosaminyltransferase [IPR045885]	0.6173344235486583	0.1542924236069568	0.8773791708714413	1.0	0.9940653749446724	2	Q10471	1
+Zinc finger, RING-type [IPR001841]	0.28848770133486	0.1530379429511669	0.8783683535598406	1.0	0.9940653749446724	19	P19474,Q7Z6E9	2
+DNA-directed RNA polymerase, RpoA/D/Rpb3-type [IPR011263]	0.6095666394112915	0.142711016123322	0.8865184161684918	1.0	0.9940653749446724	2	P19387	1
+DNA-directed RNA polymerase, insert domain [IPR011262]	0.6095666394112915	0.142711016123322	0.8865184161684918	1.0	0.9940653749446724	2	P19387	1
+FF domain [IPR002713]	0.6079313164350035	0.1403508113092426	0.8883828199635029	1.0	0.9940653749446724	2	O14776	1
+KOW [IPR005824]	0.342202210397054	0.1360392508758643	0.8917902516703387	1.0	0.9940653749446724	5	Q96A35,P62701,O00267,P61254	4
+Translation elongation factor EFG/EF2, domain IV [IPR005517]	0.4858895705521502	0.1237383620363581	0.901522436543848	1.0	0.9940653749446724	3	P13639,Q96RP9	2
+Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain [IPR008152]	0.3045482202944121	0.1234324282437711	0.9017646793811656	1.0	0.9940653749446724	6	Q10567	1
+Glutamine amidotransferase [IPR017926]	0.3670212765957479	0.1233057699806607	0.9018649719193644	1.0	0.9940653749446724	4	P49915,Q9NRF8,P17812	3
+Arf GTPase activating protein [IPR001164]	0.584219133278831	0.1091415295045063	0.9130902358331834	1.0	0.9947807470829456	2	Q8N6T3	1
+Dynamin, GTPase domain [IPR001401]	0.4744103898557099	0.1079950767874582	0.913999597524553	1.0	0.9947807470829456	3	P50570	1
+MIT domain [IPR007330]	0.4726947845598438	0.1057724469521251	0.9157628982765296	1.0	0.9947807470829456	3	O75351	1
+tRNA-binding domain [IPR002547]	0.5784955028618237	0.1024394206973494	0.9184078950442632	1.0	0.9947807470829456	2	Q12904	1
+Heat shock protein DnaJ, cysteine-rich domain [IPR001305]	0.5760425183973921	0.0996639032566142	0.9206111588419564	1.0	0.9947807470829456	2	P31689	1
+JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]	0.2894348907573826	0.0888529156370199	0.9291988033575408	1.0	1.0	7	P51665,Q92905,O15372	3
+Ribosome receptor lysine/proline rich [IPR007794]	0.5600981193785863	0.0830081453199841	0.9338450629396728	1.0	1.0	2	Q9P2E9	1
+Domain of unknown function DUF4749 [IPR031847]	0.549468520032716	0.073196691909802	0.941649598802019	1.0	1.0	2	O00151	1
+ZU5 domain [IPR000906]	0.5359771054783419	0.0621564488201581	0.9504382441987558	1.0	1.0	2	Q07157	1
+Class II aldolase/adducin N-terminal [IPR001303]	0.5228945216680397	0.0528731332062998	0.9578329910398112	1.0	1.0	2	Q9UEY8	1
+Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219]	0.416679250302662	0.0506325218931724	0.9596183473295988	1.0	1.0	3	Q13464	1
+PurM-like, C-terminal domain [IPR010918]	0.4139059304703498	0.0487098430871762	0.961150531539614	1.0	1.0	3	P22102,O15067	2
+Peptidase C19, ubiquitin-specific peptidase, DUSP domain [IPR006615]	0.4102249488752546	0.0462625312271227	0.963101003065694	1.0	1.0	3	Q8TEY7,Q9Y4E8	2
+Alpha-D-phosphohexomutase, alpha/beta/alpha domain I [IPR005844]	0.4031524459472901	0.0418849169442348	0.9665904403812158	1.0	1.0	3	O95394	1
+Fragile X-related 1 protein, C-terminal region 1 [IPR032172]	0.5040883074407304	0.0417789419628044	0.9666749222325124	1.0	1.0	2	P51116	1
+Matrin/U1-C-like, C2H2-type zinc finger [IPR003604]	0.2518427518427472	0.0408209324292001	0.96743865160068	1.0	1.0	6	Q96KR1,P43243,Q5VUA4,Q15428,P09234	5
+Cyclin-like [IPR013763]	0.492641046606716	0.036205296312631	0.97111866291313	1.0	1.0	2	P14635	1
+Domain of unknown function DUF1747 [IPR013719]	0.4885527391659959	0.0344128388889808	0.9725479455834072	1.0	1.0	2	Q9Y5B9	1
+HDGF-related, PWWP domain [IPR035496]	0.3852760736196343	0.0325898605389121	0.9740016556546912	1.0	1.0	3	Q7Z4V5,P51858	2
+Sec63 domain [IPR004179]	0.4807849550286268	0.0312762852514404	0.9750492027815822	1.0	1.0	2	O75643	1
+26S proteasome regulatory subunit Rpn7, N-terminal [IPR045135]	0.4775143090760541	0.0300564910515277	0.9760220001505766	1.0	1.0	2	Q13098	1
+Band 4.1, C-terminal [IPR008379]	0.4754701553556943	0.0293232658489515	0.9766067714147202	1.0	1.0	2	P11171	1
+FERM adjacent (FA) [IPR014847]	0.4754701553556943	0.0293232658489515	0.9766067714147202	1.0	1.0	2	P11171	1
+SAB domain [IPR007477]	0.4754701553556943	0.0293232658489515	0.9766067714147202	1.0	1.0	2	P11171	1
+Vps4 oligomerisation, C-terminal [IPR015415]	0.3738241308793391	0.0278361212503767	0.9777928565249274	1.0	1.0	3	O75351,P55072	2
+SCP2 sterol-binding domain [IPR003033]	0.3717791411042929	0.0270764318983719	0.9783987724882834	1.0	1.0	3	P51659,Q6YN16	2
+GTP binding protein, second domain [IPR031662]	0.4582992641046728	0.0239869711271811	0.9808630012525468	1.0	1.0	2	P55039	1
+Ribosomal protein L11, N-terminal [IPR020784]	0.4574816026165246	0.0237670932849695	0.9810383883854176	1.0	1.0	2	P30050	1
+Ribosomal protein L11, C-terminal [IPR020783]	0.4574816026165246	0.0237670932849695	0.9810383883854176	1.0	1.0	2	P30050	1
+BAT2, N-terminal [IPR009738]	0.4460343417825141	0.020981957094216	0.9832600486611782	1.0	1.0	2	Q9Y520	1
+BZW1/2, W2 domain [IPR043510]	0.4276369582992772	0.0175217121026696	0.9860204117512588	1.0	1.0	2	Q9Y6E2	1
+Post-SET domain [IPR003616]	0.2369613590769341	0.0166588394057871	0.9867087839963156	1.0	1.0	4	O15047	1
+Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375]	0.3226993865030639	0.0152687120988164	0.9878178037013334	1.0	1.0	3	Q86TI2,P48147	2
+Nuclear transport factor 2, eukaryote [IPR018222]	0.3184103500577024	0.0146949693228949	0.988275532825032	1.0	1.0	3	Q9UN86	1
+Nuclear transport factor 2 domain [IPR002075]	0.3184103500577024	0.0146949693228949	0.988275532825032	1.0	1.0	3	Q9UN86	1
+Lens epithelium-derived growth factor, integrase-binding domain [IPR021567]	0.3851185609157886	0.0130117826862614	0.989618392432524	1.0	1.0	2	Q7Z4V5	1
+Vacuolar protein sorting-associated protein 4, MIT domain [IPR045253]	0.3736713000817755	0.0123655682467606	0.990133955442666	1.0	1.0	2	O75351	1
+Glutathione S-transferase, C-terminal [IPR004046]	0.2461661131810706	0.0118663665783135	0.9905322315086396	1.0	1.0	9	P28161	1
+Alpha-D-phosphohexomutase, C-terminal [IPR005843]	0.3618152085036874	0.0118640423159149	0.9905340858711866	1.0	1.0	2	O95394	1
+Alpha-D-phosphohexomutase, alpha/beta/alpha domain II [IPR005845]	0.3618152085036863	0.0118640423159149	0.9905340858711866	1.0	1.0	2	P36871	1
+Alpha-D-phosphohexomutase, alpha/beta/alpha domain III [IPR005846]	0.3618152085036863	0.0118640423159149	0.9905340858711866	1.0	1.0	2	P36871	1
+Protein of unknown function DUF3715 [IPR022188]	0.3565004088307526	0.011684795994722	0.9906770938298188	1.0	1.0	2	Q9UK61	1
+Ribosomal protein L26/L24, KOW domain [IPR041988]	0.349959116925602	0.0114968292837738	0.9908270594921564	1.0	1.0	2	Q96A35	1

interpro_family/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Proteasome, subunit alpha/beta [IPR001353]", "1": "Proteasome B-type subunit [IPR023333]"}