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93043b5 verified
Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
Antigen processing ubiquitination proteasome degradation 0.5460045878238674 3.675543814086308 0.000237343301777 0.2691651109504041 0.1069992725310486 77 Q92530,Q7Z6E9,Q16763,P48556,Q15386,P19474,Q9UJX4,Q13200,Q9ULT8,P25789,P30260,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,P61081,Q8TBC4,A0AVT1,Q99436,P63208,P51665,Q9UIQ6,P20618,Q93034,Q13867,O43242,Q9UJX2,P60900,Q15008,P55786,Q06323,Q96J02,Q14139 36
Class i mhc mediated antigen processing presentation 0.4859766053803556 3.3063804076538843 0.0009450968446573 0.7132266990998092 0.1069992725310486 93 Q92530,Q7Z6E9,Q16763,P48556,Q15386,P19474,Q9UJX4,Q13200,Q9ULT8,P25789,P30260,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,P61081,Q8TBC4,A0AVT1,Q99436,P63208,P51665,Q9UIQ6,P20618,Q93034,Q13867,O43242,Q9UJX2,P60900,Q15008,P55786,Q15436,Q06323,Q96J02,Q14139 37
Auf1 hnrnp d0 binds and destabilizes mrna 0.6126992220544354 3.2978612694983847 0.0009742425636185 0.7240682555720971 0.1069992725310486 41 P04792,P48556,Q13200,Q04637,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q99436,P51665,P20618,O43242,P60900,Q15008,Q06323,Q92530 20
Neddylation 0.529186404152087 3.1697301032686864 0.0015258059282923 0.86696312007428 0.1069992725310486 62 Q9UNS2,P48556,Q13200,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P61081,P28070,P61201,Q8TBC4,Q99436,P61964,P63208,Q9UBW8,P51665,P20618,Q93034,Q99627,O43242,P60900,Q15008,Q5TAQ9,Q06323,Q92530 28
Synthesis of dna 0.5057944099310957 3.1688400074756253 0.0015304861905878 0.867784351071267 0.1069992725310486 68 Q16763,P51530,P48556,Q9UJX4,Q13200,P25789,P30260,P25787,P49721,Q99460,Q9BRT9,P28072,P28074,Q9UL46,P28070,O00231,Q99436,P41440,P63208,P49642,P39748,Q07864,P51665,P15927,P09884,P20618,O43242,P60900,Q9UJX2,Q15008,Q06323,Q92530 32
Mapk6 mapk4 signaling 0.583732357883407 3.163223600927884 0.0015603243815527 0.8729021788919521 0.1069992725310486 46 P04792,P48556,Q13200,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q9UNM6,O00231,Q99436,P06493,P17612,P35998,P51665,P25685,P60953,P20618,O43242,Q13177,P60900,Q15008,Q06323,Q92530 27
Mitotic g1 phase and g1 s transition 0.5112696268565432 3.1234097242383236 0.0017876869662294 0.9059235795654204 0.1069992725310486 65 P30153,P48556,P00374,Q13200,P63151,P25789,P31350,P27694,P33991,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q9UNM6,O00231,P14635,Q99436,P06493,P63208,P49642,P35998,Q07864,P51665,P15927,P33993,P62191,P09884,P20618,P11802,O43242,Q13547,O14818,P60900,P06400,Q15008,P25205,Q06323,Q92530 41
Dectin 1 mediated noncanonical nf kb signaling 0.5965367037052889 3.106527024740306 0.0018929900487676 0.9181616802766828 0.1069992725310486 40 P48556,Q13200,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P61081,P28070,Q8TBC4,Q99436,P63208,P51665,P20618,O43242,P60900,Q15008,Q06323,Q92530 21
Tnfr2 non canonical nf kb pathway 0.5965367037052889 3.106527024740306 0.0018929900487676 0.9181616802766828 0.1069992725310486 40 P48556,Q13200,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P61081,P28070,Q8TBC4,Q99436,P63208,P51665,P20618,O43242,P60900,Q15008,Q06323,Q92530 21
Clec7a dectin 1 signaling 0.5819038596173964 3.0715219219303846 0.002129705249952 0.9401755410191032 0.1069992725310486 42 P48556,Q13200,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P61081,P28070,Q8TBC4,Q99436,P63208,P51665,P20618,O43242,P60900,Q15008,Q06323,Q92530 21
S phase 0.4847101928782604 3.026841908544693 0.0024712316687305 0.9619379423926 0.1069992725310486 77 Q92530,Q16763,P51530,P48556,Q9UJX4,Q13200,P25789,P27694,P30260,P33991,P25787,P49721,Q99460,Q9BRT9,P28072,P28074,Q9UL46,P28070,Q9UNM6,O00231,Q99436,P41440,P63208,P49642,P35998,P39748,Q07864,P51665,P33993,P62191,P09884,P20618,P11802,Q8N3U4,O43242,O14818,Q9UJX2,P06400,P60900,Q15008,P25205,Q06323,P15927 43
Degradation of gli1 by the proteasome 0.5820919308016109 2.9932028836405467 0.0027606616321873 0.9740576143728096 0.1069992725310486 40 Q92530,P48556,Q13200,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q99436,P63208,P51665,P20618,O43242,P60900,Q15008,Q06323,Q96J02 20
Signaling by the b cell receptor bcr 0.588875028004418 2.986082329014394 0.0028257655584389 0.976201204752451 0.1069992725310486 39 P48556,Q13200,P25789,P62993,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q99436,P63208,P51665,P20618,O43242,P60900,Q15008,Q06323,Q92530 20
Scf skp2 mediated degradation of p27 p21 0.5880028715071904 2.979312308025016 0.0028889615924765 0.9781125420440222 0.1069992725310486 39 P48556,Q13200,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q99436,P63208,P51665,P20618,O43242,P60900,Q15008,P11802,Q06323,Q92530 20
Dna replication 0.4828550021209398 2.966808338023442 0.0030090847279216 0.9813329157634588 0.1069992725310486 73 Q16763,P51530,P48556,Q9UJX4,Q13200,P25789,P27694,P30260,P33991,P25787,P49721,Q99460,Q9BRT9,P28072,P28074,Q9UL46,P28070,Q9UNM6,O00231,Q14974,Q99436,P41440,P63208,P49642,P35998,P39748,Q07864,P51665,P15927,P33993,P62191,P09884,P20618,O43242,O14818,P60900,Q9UJX2,Q15008,P25205,Q06323,Q92530,O60684 42
Cyclin a cdk2 associated events at s phase entry 0.5780027458698334 2.960868035682516 0.003067733521433 0.9827286234418644 0.1069992725310486 40 P48556,Q13200,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q99436,P63208,P51665,P20618,O43242,P60900,Q15008,P11802,Q06323,Q92530 20
C type lectin receptors clrs 0.5625476027859863 2.9488357687040807 0.0031897343256048 0.9853068453447972 0.1069992725310486 44 P48556,Q13200,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P61081,P28070,Q8TBC4,Q9UNM6,O00231,Q99436,P17612,P63208,P35998,P51665,P62191,P20618,O43242,Q13177,P60900,Q15008,Q06323,Q92530 27
Transcriptional regulation by runx2 0.5436115806075675 2.93967791605108 0.0032855358187904 0.9870587889129178 0.1069992725310486 51 Q96PK6,P48556,Q13200,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q9UNM6,O00231,P14635,Q99436,P06493,P63208,P35998,P51665,P62191,P20618,O43242,O14818,P17931,P06400,Q07812,P60900,Q15008,P11802,Q06323,Q92530 31
Regulation of mrna stability by proteins that bind au rich elements 0.5181091992692181 2.914147289954216 0.0035666158617242 0.9910841228253104 0.1069992725310486 58 P04792,Q92945,Q92973,P48556,Q13200,Q9Y2L1,Q04637,P25789,Q01105,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q99436,P51665,P20618,O43242,P60900,Q15008,Q06323,Q92530 24
Beta catenin independent wnt signaling 0.5453348849900416 2.9060900554180344 0.0036597610250681 0.9921198835424924 0.1069992725310486 49 P48556,Q13200,P61586,P25789,P09497,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,P53680,Q99436,P51665,P20618,O43242,P60900,Q15008,Q06323,Q92530 21
Pcp ce pathway 0.5497671231289515 2.900154255722486 0.0037297905870905 0.9928186271939462 0.1069992725310486 47 P48556,Q13200,P61586,P25789,P09497,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,P53680,Q99436,P51665,P20618,O43242,P60900,Q15008,Q06323,Q92530 21
Switching of origins to a post replicative state 0.5389059890114333 2.8981958111930037 0.0037531618625357 0.993037760690796 0.1069992725310486 51 Q16763,P48556,Q9UJX4,Q13200,P25789,P30260,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,O00231,Q99436,P63208,P51665,P20618,O43242,P60900,Q9UJX2,Q15008,Q06323,Q92530 24
Defective cftr causes cystic fibrosis 0.5687279834127064 2.887108918134126 0.0038879961349869 0.9941776615777322 0.1069992725310486 40 P48556,Q13200,Q9BUN8,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UBV2,Q9UL46,P28070,Q99436,P51665,P20618,O43242,P60900,Q15008,Q06323,Q92530 20
Abc transporter disorders 0.5687279834127065 2.887108918134126 0.0038879961349869 0.9941776615777322 0.1069992725310486 40 P48556,Q13200,Q9BUN8,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UBV2,Q9UL46,P28070,Q99436,P51665,P20618,O43242,P60900,Q15008,Q06323,Q92530 20
Downstream signaling events of b cell receptor bcr 0.5826509932481174 2.881054051020786 0.0039634766489831 0.9947322715481632 0.1069992725310486 38 P48556,Q13200,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q99436,P63208,P51665,P20618,O43242,P60900,Q15008,Q06323,Q92530 19
Fceri mediated nf kb activation 0.5671893495005882 2.8748160017131728 0.0040426300890965 0.9952572492562926 0.1069992725310486 40 P48556,Q13200,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q99436,P63208,P51665,P20618,O43242,P60900,Q15008,Q06323,Q92530 19
Fc epsilon receptor fceri signaling 0.5534842966339014 2.873574095327491 0.0040585586441101 0.9953563992259498 0.1069992725310486 44 P48556,Q13200,P25789,P62993,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q99436,P63208,P51665,P20618,O43242,P60900,Q15008,Q06323,Q92530 20
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 0.5503689652453168 2.8656675867325343 0.0041613094994616 0.9959480588823024 0.1069992725310486 45 Q16763,P48556,Q9UJX4,Q13200,P25789,P30260,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q99436,P51665,P20618,O43242,P60900,Q9UJX2,Q15008,Q06323,Q92530 22
Regulation of runx2 expression and activity 0.5558893231859745 2.8601273811491317 0.0042347087508718 0.9963239938158168 0.1069992725310486 42 P48556,Q13200,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q99436,P63208,P51665,P20618,O43242,P60900,Q15008,Q06323,Q92530 19
Hedgehog ligand biogenesis 0.5719910059480247 2.8541335060613293 0.0043154391818907 0.9966973535054946 0.1069992725310486 39 P48556,Q13200,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UBV2,Q9UL46,P28070,Q99436,P51665,P20618,O43242,P60900,Q15008,Q06323,Q92530 19
Negative regulation of notch4 signaling 0.5714474206679243 2.8498540575193605 0.0043739293843123 0.9969439556049496 0.1069992725310486 39 P48556,Q13200,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q99436,P63208,P51665,P20618,O43242,P60900,Q15008,Q06323,Q92530 19
Apc c mediated degradation of cell cycle proteins 0.5323655992618357 2.8402474326764655 0.0045078553674924 0.9974415131646452 0.107592865943102 51 Q16763,P48556,Q9UJX4,Q13200,P25789,P30260,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,O00231,Q99436,P63208,P51665,P20618,O43242,P60900,Q9UJX2,Q15008,Q06323,Q92530 24
Degradation of beta catenin by the destruction complex 0.542323575570229 2.836500516684355 0.0045610904563313 0.9976160181911962 0.107592865943102 47 P48556,Q13200,P25789,Q13363,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q99436,P63208,P51665,P20618,O43242,P60900,Q15008,Q06323,Q92530 20
Hedgehog on state 0.5607631595820051 2.823298546387844 0.0047532287178728 0.9981526172858636 0.1076842091899704 40 P48556,Q13200,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q99436,P51665,P20618,O43242,P60900,Q15008,Q96J02,Q06323,Q92530 19
Tcr signaling 0.5527755213835246 2.819522609519849 0.0048095142635944 0.9982856063451804 0.1076842091899704 41 P48556,Q13200,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q99436,P63208,P51665,P20618,O43242,P60900,Q15008,Q06323,Q92530 19
Dna replication pre initiation 0.5159556832360246 2.770891092189698 0.0055903121250207 0.9993921128155148 0.1187713893728215 54 P48556,Q13200,P25789,P27694,P33991,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q9UNM6,O00231,Q14974,Q99436,P49642,P35998,Q07864,P51665,P15927,P33993,P62191,P09884,P20618,O43242,O14818,P60900,Q15008,P25205,Q06323,Q92530,O60684 33
Mapk family signaling cascades 0.4617979087468344 2.764096438517391 0.0057080666244018 0.999480143987426 0.1187713893728215 76 Q92530,P04792,P48556,Q13200,Q9UQ13,P25789,Q06124,P62993,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q9UNM6,O00231,P35609,Q99436,P06493,P17612,P35998,P51665,P25685,P60953,Q9Y490,P20618,Q96S59,O43242,Q13177,P49354,P18206,P60900,Q15008,Q06323,P30153 36
Cross presentation of soluble exogenous antigens endosomes 0.5798863695275867 2.756399117137711 0.0058441637465809 0.9995661394852936 0.1187713893728215 36 Q99436,Q15008,P25787,P49721,P48556,O43242,Q99460,P51665,P28072,P28074,P60900,Q13200,Q9UL46,P28070,P20618,P25789,Q06323,Q92530 18
Degradation of axin 0.5798863695275867 2.756399117137711 0.0058441637465809 0.9995661394852936 0.1187713893728215 36 Q99436,Q15008,P25787,P49721,P48556,O43242,Q99460,P51665,P28072,P28074,P60900,Q13200,Q9UL46,P28070,P20618,P25789,Q06323,Q92530 18
Metabolism of polyamines 0.5712281207396004 2.7400997724742604 0.0061420536177427 0.9997079754183246 0.1197761727241366 37 Q99436,Q15008,P25787,P49721,P48556,O43242,Q99460,P51665,P28072,P28074,P60900,Q13200,Q9UL46,P28070,P20618,P25789,Q06323,Q92530 18
Regulation of runx3 expression and activity 0.5704649185672785 2.734221279137797 0.0062528007921913 0.9997479497062935 0.1197761727241366 37 Q99436,Q15008,P25787,P49721,P48556,O43242,Q99460,P51665,P28072,P28074,P60900,Q13200,Q9UL46,P28070,P20618,P25789,Q06323,Q92530 18
Orc1 removal from chromatin 0.5348273945257686 2.7340377249903645 0.0062562875987626 0.9997491152716308 0.1197761727241366 45 P48556,Q13200,P25789,P33991,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q9UNM6,O00231,Q99436,P63208,P35998,P51665,P33993,P62191,P20618,O43242,O14818,P60900,Q15008,Q06323,Q92530 26
Regulation of ras by gaps 0.5670087511271786 2.707554078901456 0.0067781026783226 0.9998746444675124 0.1226558032611543 37 Q99436,Q15008,P25787,P49721,P48556,O43242,Q99460,P51665,P28072,P28074,P60900,Q13200,Q9UL46,P28070,P20618,P25789,Q06323,Q92530 18
Degradation of dvl 0.5670087511271786 2.707554078901456 0.0067781026783226 0.9998746444675124 0.1226558032611543 37 Q99436,Q15008,P25787,P49721,P48556,O43242,Q99460,P51665,P28072,P28074,P60900,Q13200,Q9UL46,P28070,P20618,P25789,Q06323,Q92530 18
Uch proteinases 0.5287759368411822 2.665339612458974 0.0076910608896361 0.9999627985603484 0.1336827820422277 44 P48556,Q13200,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q99436,Q8NB78,P51665,P20618,O43242,P60900,Q15008,Q06323,Q92530 19
Cdt1 association with the cdc6 orc origin complex 0.5607055418624439 2.658723389299096 0.007843733199532 0.9999696411356296 0.1345658643711922 37 Q99436,Q15008,P25787,P49721,P48556,O43242,Q99460,P51665,P28072,P28074,P60900,Q13200,Q9UL46,P28070,P20618,P25789,Q06323,Q92530 18
Asymmetric localization of pcp proteins 0.5554744458222283 2.618005251910392 0.0088445443851228 0.9999919963916396 0.1410598424235998 37 Q99436,Q15008,P25787,P49721,P48556,O43242,Q99460,P51665,P28072,P28074,P60900,Q13200,Q9UL46,P28070,P20618,P25789,Q06323,Q92530 18
Abc family proteins mediated transport 0.5139983586003862 2.5720440081735947 0.0101100039476302 0.9999985197282368 0.1512097121308643 46 P48556,Q13200,Q9BUN8,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UBV2,Q9UL46,P28070,Q99436,P51665,P05198,P20618,O43242,P60900,Q15008,Q06323,Q92530 21
Cellular response to hypoxia 0.5425216638173526 2.566295864531735 0.0102791109244586 0.9999988187956466 0.1512097121308643 38 Q99436,Q15008,P25787,P49721,P48556,O43242,Q99460,P51665,P28072,P28074,P60900,Q13200,Q9UL46,P28070,P20618,P25789,Q06323,Q92530 18
Runx1 regulates transcription of genes involved in differentiation of hscs 0.5221755962030189 2.565526048128965 0.0103019485933215 0.9999988542581656 0.1512097121308643 41 P48556,Q13200,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q99436,P51665,P20618,O43242,P60900,Q15008,Q96J02,Q06323,Q92530 19
Stabilization of p53 0.5382912756228022 2.532497076017179 0.0113253314365127 0.9999997078871824 0.1558121211564691 38 Q99436,Q15008,P25787,P49721,P48556,O43242,Q99460,P51665,P28072,P28074,P60900,Q13200,Q9UL46,P28070,P20618,P25789,Q06323,Q92530 18
G1 s dna damage checkpoints 0.5382912756228022 2.532497076017179 0.0113253314365127 0.9999997078871824 0.1558121211564691 38 Q99436,Q15008,P25787,P49721,P48556,O43242,Q99460,P51665,P28072,P28074,P60900,Q13200,Q9UL46,P28070,P20618,P25789,Q06323,Q92530 18
Regulation of pten stability and activity 0.5239291705388752 2.522477061059881 0.0116531550219625 0.9999998115087048 0.1558121211564691 40 Q99436,Q15008,P25787,P49721,P48556,O43242,Q99460,P51665,P28072,P28074,P60900,Q13200,Q9UL46,P28070,P20618,P25789,Q06323,Q92530 18
Adaptive immune system 0.391731335989218 2.4996169364439793 0.0124327659896685 0.9999999335378998 0.1558121211564691 149 Q92530,Q7Z6E9,Q16763,P30153,Q14203,P48556,Q15386,Q9Y6G9,P19474,Q9UJX4,Q13200,P68036,Q9ULT8,P25789,P33176,Q06124,O94874,P09429,P30260,P62993,P25787,P49721,Q99460,P28072,P28074,Q9UJW0,Q9UL46,P28070,P61081,Q8TBC4,Q9UNM6,P53680,A0AVT1,O00231,O43237,P52732,Q99436,O95486,P17612,P63208,P35998,Q10567,P51665,O75935,Q9BUF5,P68371,P63104,P60953,Q9BXS5,Q9UIQ6,P62191,P50570,P20618,Q5T4S7,Q93034,O43747,Q13409,Q7Z6Z7,Q13867,O43242,Q13177,Q9UJX2,P60900,Q15008,P55786,Q15436,Q06323,Q96J02,Q14139 69
Antigen processing cross presentation 0.5032263126897192 2.495215018918042 0.012588082512758 0.9999999460067298 0.1558121211564691 47 P48556,Q13200,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q99436,P51665,Q9UIQ6,P20618,O43242,P60900,Q15008,Q06323,Q92530 19
Hedgehog off state 0.4978667077010149 2.466093851297267 0.0136595539117156 0.9999999871335532 0.1592501604143031 48 Q92530,P48556,Q13200,P25789,P10644,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q9UNM6,O00231,Q99436,P17612,P63208,P35998,P51665,Q9BUF5,P68371,P20618,O43242,P60900,Q15008,Q06323,Q96J02 27
Regulation of hmox1 expression and activity 0.5070369836919443 2.463675084225537 0.0137520711863388 0.999999988633059 0.1592501604143031 43 P48556,Q13200,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q99436,P63208,P51665,P20618,O43242,P60900,Q15008,Q06323,Q92530 19
Signaling by hedgehog 0.4843023386205164 2.450184425299153 0.0142783061033675 0.999999994383708 0.1592501604143031 53 Q92530,P48556,Q13200,P25789,P10644,P25787,P49721,Q99460,P28072,P28074,Q9UBV2,Q9UL46,P28070,Q9UNM6,O00231,Q99436,P17612,P63208,P35998,P51665,Q9BUF5,P68371,P62191,Q6P1J9,P20618,O43242,P60900,Q15008,Q06323,Q96J02 30
Hsf1 dependent transactivation 0.7285203452711866 2.427209431319508 0.0152154696233755 0.9999999984013672 0.1592501604143031 13 Q96B36,P25685,P04792,Q02790 4
Signaling by notch4 0.5040826554561891 2.4246478850099176 0.0153232409286265 0.999999998616557 0.1592501604143031 42 P48556,Q13200,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q99436,P63208,P51665,P20618,O43242,P60900,Q15008,Q06323,Q92530 19
Signaling by interleukins 0.4011276389465289 2.3850141778145653 0.0170784631506843 0.9999999998689604 0.1592501604143031 99 Q92530,P48556,P04179,P04083,Q13200,P08670,P11233,P25789,Q06124,P51452,P09429,P14174,Q99439,P62993,P25787,P49721,O14979,Q99460,P28072,P28074,Q9UL46,P28070,Q00169,Q9UNM6,O00231,Q99436,P17612,P63208,P26038,P35998,P51665,P63104,P60953,P20618,Q13126,O43242,Q13177,P40763,P60900,Q15008,Q15418,P22626,Q06323,P30153 44
Cell cycle checkpoints 0.3710591537165766 2.372207018501356 0.0176821803683724 0.9999999999418002 0.1592501604143031 115 Q92530,Q16763,Q9UQ84,P51530,P48556,Q9NXR7,Q9Y6G9,Q9UJX4,Q13200,Q92547,O43683,O43264,P25789,P27694,P30260,Q04917,P33991,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q9UNM6,O00231,O43237,P14635,Q99436,P06493,P35998,P51665,Q9Y266,P33993,P63104,P62191,Q9P258,Q7Z460,P20618,Q15008,Q13409,O43242,Q15691,Q8NFH4,Q9UJX2,P60900,P15927,Q06323,P30153 49
The role of gtse1 in g2 m progression after g2 checkpoint 0.4842461617633138 2.325296978860916 0.0200560857350389 0.9999999999976188 0.1687521608661555 47 P48556,Q13200,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,O00231,Q99436,P51665,Q9BUF5,P20618,O43242,Q15691,P60900,Q15008,Q06323,Q92530 21
Transcriptional regulation by runx3 0.4908073673153081 2.309901239070354 0.020893622462248 0.9999999999992304 0.1735878947964127 42 Q99436,Q15008,P25787,P49721,P48556,O43242,Q99460,P51665,P28072,P28074,P60900,Q13200,Q9UL46,P28070,P20618,P25789,Q06323,Q92530 18
Attenuation phase 0.7205294464128315 2.2803082003609108 0.0225894157907209 0.999999999999922 0.1842013472811256 11 P25685,P04792,Q02790 3
Hsf1 activation 0.6947640617147505 2.2565409068470026 0.0240367764401367 0.999999999999989 0.1936133029111018 13 P25685,P04792,Q02790 3
Retrograde transport at the trans golgi network 0.7318939898382348 2.227280071856615 0.0259285615389703 0.9999999999999992 0.2025191635374131 10 P40616,Q5VZE5,P20645,P83436 4
Signaling by vegf 0.6240209448248912 2.2209835631171684 0.0263520746984282 0.9999999999999996 0.2035736296878581 18 P61586,P04792 2
G2 m checkpoints 0.4117364853712477 2.18081282989363 0.0291972632263612 1.0 0.2203976269829901 74 Q9UQ84,P51530,P48556,Q9NXR7,Q13200,Q92547,P25789,P27694,Q04917,P33991,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q9UNM6,O00231,P14635,Q99436,P06493,P35998,P51665,P15927,P33993,P63104,P62191,P20618,O43242,O14818,P60900,Q15008,Q06323,Q92530 35
Transcriptional regulation by runx1 0.4256132781414956 2.1547468706025903 0.031181647841131 1.0 0.2290129887961947 63 Q92530,P48556,Q99873,Q12824,Q13200,P25789,Q06124,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,O15047,Q99436,P61964,P51665,P20618,O43242,P17931,P60900,Q15008,Q06323,Q96J02 25
Interleukin 1 family signaling 0.4598634327953416 2.103003043612165 0.0354655034362183 1.0 0.2488072265807574 47 P48556,Q13200,P25789,Q06124,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q99436,P63208,P51665,P20618,O43242,P40763,P60900,Q15008,Q06323,Q92530 21
Programmed cell death 0.3901966333118645 2.066680747353269 0.0387642464848947 1.0 0.2582289918821276 89 O43633,P48556,Q13200,Q15149,P08670,P25789,P09429,Q04917,Q8WUM4,P49721,P25787,Q9UDY2,Q99460,P28072,P28074,Q9UL46,P28070,Q9UNM6,O00231,Q14974,Q99436,P41440,P35998,P51665,P63104,P20618,O00273,O43242,Q9NR28,Q13177,P49354,P40763,Q07812,P60900,Q15008,Q06323,Q92530 37
Metabolism of vitamins and cofactors 0.4914088424133336 2.0629721598499957 0.0391152733404327 1.0 0.2582289918821276 36 P43490,P02656,P34896,O75874 4
Apoptosis 0.397304445165636 2.045987853305591 0.0407575657626648 1.0 0.2582289918821276 79 P48556,Q13200,Q15149,P08670,P25789,P09429,Q04917,P25787,P49721,Q9UDY2,Q99460,P28072,P28074,Q9UL46,P28070,Q9UNM6,O00231,Q14974,Q99436,P35998,P51665,P63104,P20618,O00273,O43242,Q9NR28,Q13177,P49354,P40763,P60900,Q07812,Q15008,Q06323,Q92530 34
Transcriptional activation of mitochondrial biogenesis 0.6932199333666103 2.042667248123053 0.0410853891040368 1.0 0.2584466619353934 10 P48735 1
Separation of sister chromatids 0.3891311089789017 2.02715571291501 0.0426464906983174 1.0 0.2620279730812903 87 Q92530,Q16763,P48556,Q9Y6G9,Q9UJX4,Q13200,O43264,O43683,P25789,P30260,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q9UNM6,O00231,O43237,Q99436,P35998,P51665,Q9Y266,Q9BUF5,P68371,P62191,Q9P258,Q7Z460,P20618,Q13409,Q8N3U4,O43242,Q15691,Q8NFH4,Q9UJX2,P60900,Q15008,Q06323,P30153 40
Interconversion of nucleotide di and triphosphates 0.6290060883844516 2.025118029887145 0.0428552459548612 1.0 0.2620915736406097 15 Q9H773 1
Intracellular signaling by second messengers 0.3971095357604286 2.0013231073896285 0.0453575811123894 1.0 0.2748502965571853 72 Q92530,P48556,Q13200,P25789,Q06124,P62993,P10644,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q9UNM6,O00231,Q99436,P17612,P35998,P51665,P62191,O95983,P20618,Q6IAA8,Q96B36,O43242,Q13547,Q8WXI9,P60900,Q15008,Q06323,P30153 32
Signaling by insulin receptor 0.6379180192365965 1.9616519270480797 0.0498030222692111 1.0 0.2950214906620088 13 P62993,Q15904,Q06124 3
Signaling by receptor tyrosine kinases 0.3789145130416785 1.9509380325999996 0.0510644176966674 1.0 0.2993435749762398 91 P04792,Q9UQB8,Q99570,Q15904,P16949,O14786,P61586,P11233,Q06124,P51452,P42566,P62993,Q8WX92,P61201,P30876,P53680,P60953,P50570,Q93034,P21281,Q96S59,Q13685,P11047,Q13177,P40763,Q07812,Q00535,Q15418,Q96J02 29
Signaling by notch 0.428331533612783 1.9323296203480165 0.0533188346969997 1.0 0.3089218448891957 54 Q92530,P48556,P67809,Q13200,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UBV2,Q9UL46,P28070,Q99436,P63208,P51665,P20618,O43242,P60900,Q15008,Q06323,Q96J02 22
Signaling by wnt 0.3885020121793474 1.9147335412232604 0.0555264937623705 1.0 0.3175346245025603 75 P48556,Q13200,P61586,P25789,Q13363,P09497,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,P53680,Q99436,P63208,P51665,P20618,O43242,P60900,Q15008,Q06323,Q92530 23
Interleukin 1 signaling 0.4412806852097786 1.9036904625191509 0.0569505092991584 1.0 0.3228825012196923 45 P48556,Q13200,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q99436,P63208,P51665,P20618,O43242,P60900,Q15008,Q06323,Q92530 19
Gene and protein expression by jak stat signaling after interleukin 12 stimulation 0.5205396851003984 1.8801750078564436 0.0600842305269415 1.0 0.3348998671986911 24 P14174,Q99439,O14979,P04179,Q13177,Q9UL46,Q00169,P60953,P11233,Q13126 10
Disorders of transmembrane transporters 0.3855481085025893 1.8604551011886792 0.0628211651336119 1.0 0.3443433989273914 70 P48556,Q13200,Q9BUN8,P25789,P25787,P49721,Q99460,O00400,P28072,P28074,Q9UBV2,Q9UL46,P28070,Q99436,P35613,P51665,P20618,O43242,Q8NFH4,P60900,Q15008,Q06323,Q92530 23
Pten regulation 0.4086934472307805 1.853280267458166 0.0638421979574799 1.0 0.3484939814125247 59 P48556,Q13200,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q99436,P51665,O95983,P20618,O43242,Q8WXI9,P60900,Q15008,Q06323,Q92530 20
Mitotic g2 g2 m phases 0.3829689419176442 1.8444043927108753 0.0651242276227215 1.0 0.3497118076813623 74 Q92530,Q14203,P48556,Q13200,P63151,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q9UNM6,O00231,P14635,Q99436,P06493,P17612,P63208,P35998,P51665,O75935,Q9BUF5,P68371,P62191,P20618,Q13409,O95684,O43242,Q15691,P60900,Q15008,Q06323,P30153 35
Signaling by scf kit 0.85441516458168 1.8005343805842482 0.0717762999348012 1.0 0.3694023721574697 4 P40763,Q06124 2
Peptide hormone metabolism 0.6889846116625604 1.7851508544027856 0.0742368510706219 1.0 0.3728778717273444 8 Q8TAG9,O00471 2
Cytokine signaling in immune system 0.347060750213591 1.771711471010373 0.0764424645212675 1.0 0.3810584740852621 157 P48556,P04179,P04083,P19474,Q04637,P25789,Q06124,P14174,Q99439,P62993,P25787,P49721,Q9Y4X5,O14979,Q13526,P28072,P28074,Q00169,P28070,Q13325,Q8TBC4,Q99436,P51665,P20618,Q13126,O43242,Q8NFH4,P40763 28
Dna damage reversal 0.957890433360589 1.7606598695195967 0.0782959888529253 1.0 0.3888308318598284 2 Q9C0B1 1
Signaling by ntrks 0.4731548122013886 1.7245122422318224 0.0846154108424619 1.0 0.4139887323070082 30 P51452,P62993,Q8WX92,P40763,Q07812,Q00535,P50570,Q15418,P61586,P11233,Q06124 11
Tcf dependent signaling in response to wnt 0.3992556745278657 1.70500473933111 0.0881935405223299 1.0 0.4194831936265693 57 Q92530,P48556,Q13200,P25789,Q13363,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q9UNM6,O00231,Q99436,P35998,P51665,P63104,P62191,Q6P1J9,P20618,O43242,Q13547,P60900,Q15008,Q06323,P30153 27
Diseases of signal transduction by growth factor receptors and second messengers 0.3304645149723259 1.7045476335869256 0.088278825002412 1.0 0.4194831936265693 122 Q14789,Q92530,Q92734,Q96PU8,Q14203,P48556,Q13200,Q9UQ13,P25789,P33176,Q06124,Q13363,P35579,Q86WB0,P62993,P25787,P49721,Q8IWJ2,Q99460,P28072,P28074,Q9UBV2,Q9UL46,P28070,P30876,O00231,Q99436,P63208,P51665,Q9Y490,P20618,Q96B36,Q15008,Q16630,Q9NRY5,O95684,O43242,P18206,P40763,P60900,O43252,Q06323,P30153 43
Nucleotide salvage 0.7225773530532675 1.7017643259513096 0.0887995564283463 1.0 0.4204452116195181 6 Q9BZX2,P55263 2
Interleukin 12 family signaling 0.4703237097382974 1.679221110253748 0.0931089592300213 1.0 0.4330877997987966 29 P14174,Q99439,O14979,P04179,Q13177,P40763,Q9UL46,Q00169,P60953,P11233,Q13126 11
Signaling by erbb2 0.6899913716452714 1.6571149099197544 0.0974962452580379 1.0 0.444112206847821 7 P62993,P61586 2
Degradation of the extracellular matrix 0.6842305320426232 1.6315025945801849 0.1027843128303107 1.0 0.4634064069926297 7 P20810,P11047,P07384,P35613 4
Hiv infection 0.3205535633510226 1.6035848207759364 0.1088055988147798 1.0 0.4839467879943573 115 O43633,P48556,Q9H3P2,Q13200,O00267,P25789,P25787,P49721,Q99460,Q8WX92,P28072,P28074,Q9UL46,P28070,P30876,P53680,O00231,Q99436,P43487,Q99816,P63208,P51665,Q08945,Q9BXS5,P20618,Q93034,O43747,P17096,Q9UN37,O43242,Q8NFH4,P60900,Q15008,Q92804,Q06323,Q92530 36
Insulin processing 0.8017711373831136 1.5935292802193457 0.1110415051392523 1.0 0.4873283331858883 4 Q8TAG9 1
Signaling by cytosolic fgfr1 fusion mutants 0.7305427149461127 1.5663083499191977 0.1172764471555931 1.0 0.493983829424471 5 O95684,P40763 2
Interferon gamma signaling 0.6132191568383588 1.5636557152039503 0.1178984429605902 1.0 0.4944248988918722 9 P19474,Q14258,Q06124 3
Interleukin 12 signaling 0.4629466307289315 1.544667623149306 0.1224266801034654 1.0 0.5006985895253185 26 P14174,Q99439,O14979,P04179,Q13177,Q9UL46,Q00169,P60953,P11233,Q13126 10
Smooth muscle contraction 0.6087461959642404 1.5418815118760998 0.123102389429536 1.0 0.5019081988778304 9 Q13177,Q05682,Q9Y490,P04083 4
Diseases associated with n glycosylation of proteins 0.9155237026727114 1.5357993329063644 0.1245876033976571 1.0 0.5032726556503722 3 O75340 1
Organelle biogenesis and maintenance 0.3577164363607621 1.5349043141661884 0.1248073336654052 1.0 0.5032726556503722 70 P48735,A6NIH7,Q8TAG9,Q13409,Q92973,O95684,Q9BW83,P04179,O00471,Q15691 10
Mitotic metaphase and anaphase 0.3154671536842102 1.5168844005054836 0.1292958727834754 1.0 0.5111526859513883 116 O43633,Q92530,Q92973,Q16763,P48556,Q9Y6G9,Q9UJX4,Q13200,P63151,O43264,O43683,P25789,P30260,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q9UNM6,O00231,O43237,Q14974,P14635,Q99436,P06493,Q9Y2U8,P35998,P51665,Q86XL3,Q9BUF5,P68371,Q9Y266,P62191,Q9P258,Q7Z460,P20618,Q13409,Q8N3U4,Q9UN37,O43242,Q15691,Q8NFH4,Q9UJX2,P60900,Q15008,Q06323,P30153 49
Cilium assembly 0.4024103092578602 1.5153505087726669 0.1296836636178588 1.0 0.5111526859513883 42 Q13409,A6NIH7,Q8TAG9,Q92973,O95684,Q9BW83,O00471,Q15691 8
Hdr through single strand annealing ssa 0.5538929625913751 1.510162327422675 0.1310020088308841 1.0 0.5111526859513883 13 Q9UQ84,P15927,Q92547 3
Homologous dna pairing and strand exchange 0.5538929625913751 1.510162327422675 0.1310020088308841 1.0 0.5111526859513883 13 Q9UQ84,P15927,Q92547 3
Hdr through homologous recombination hrr 0.4948267991179667 1.5079097459439752 0.1315776279547953 1.0 0.5112177839067196 19 Q9UQ84,P15927,P41440,Q92547 4
Cytoprotection by hmox1 0.3780037559530411 1.5056670826965717 0.1321526581996519 1.0 0.5119462213540769 58 P48556,Q13200,P25789,P25787,P49721,Q86X55,Q99460,P28072,P28074,Q9UL46,P28070,Q99436,P63208,P51665,P20618,O43242,P40763,P60900,Q15008,Q06323,Q92530 21
Ephb mediated forward signaling 0.5803913625036327 1.4843168332384626 0.1377248866209082 1.0 0.5165111173425555 10 O15143,O15144,P59998,P61586,Q92747 5
Signaling by pdgf 0.7103152578119685 1.4816801100360355 0.1384254318813564 1.0 0.5165111173425555 5 P40763,Q06124 2
Downstream signal transduction 0.7103152578119685 1.4816801100360355 0.1384254318813564 1.0 0.5165111173425555 5 P40763,Q06124 2
Signaling by egfr 0.6505530520278527 1.4808610252580587 0.1386436107066322 1.0 0.5165111173425555 7 P42566,Q13685,P62993,Q99961,P60953,Q06124 6
Cargo trafficking to the periciliary membrane 0.5322122052504481 1.4803720904937083 0.1387739739896432 1.0 0.5165111173425555 15 A6NIH7,Q8TAG9 2
Signaling by leptin 0.8830744071954213 1.4580997605979993 0.1448130473822604 1.0 0.5165111173425555 2 P40763 1
Interleukin 37 signaling 0.8830744071954213 1.4580997605979993 0.1448130473822604 1.0 0.5165111173425555 2 P40763 1
Deubiquitination 0.349199386643403 1.456335476213084 0.1452999030158568 1.0 0.5165111173425555 78 P48556,Q9NXR7,Q13200,P61586,P25789,Q8TEY7,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,P54727,Q14258,O00231,Q99436,Q8NB78,P51665,P20618,O43242,Q86UV5,P60900,Q15008,Q06323,Q92530 26
Cellular response to chemical stress 0.3505231977294063 1.449522916476804 0.147191605293254 1.0 0.5165111173425555 67 P48556,P04179,Q13200,P25789,P25787,P49721,Q86X55,Q99460,P28072,P28074,Q9UL46,P28070,Q99436,P63208,P51665,P20618,O43242,P40763,P60900,Q15008,Q06323,Q92530 22
Interleukin 15 signaling 0.8793949304987738 1.4431755193766571 0.1489710338436884 1.0 0.5165111173425555 2 P40763 1
Downstream signaling of activated fgfr1 0.8793949304987733 1.443175519376654 0.1489710338436893 1.0 0.5165111173425555 2 Q06124 1
Tie2 signaling 0.8793949304987733 1.443175519376654 0.1489710338436893 1.0 0.5165111173425555 2 Q06124 1
Signal regulatory protein family interactions 0.8793949304987733 1.443175519376654 0.1489710338436893 1.0 0.5165111173425555 2 Q06124 1
Stat5 activation downstream of flt3 itd mutants 0.8793949304987733 1.443175519376654 0.1489710338436893 1.0 0.5165111173425555 2 Q06124 1
Pi 3k cascade fgfr1 0.8793949304987733 1.443175519376654 0.1489710338436893 1.0 0.5165111173425555 2 Q06124 1
Activated ntrk2 signals through frs2 and frs3 0.8793949304987733 1.443175519376654 0.1489710338436893 1.0 0.5165111173425555 2 Q06124 1
Downstream signaling of activated fgfr4 0.8793949304987733 1.443175519376654 0.1489710338436893 1.0 0.5165111173425555 2 Q06124 1
Pi 3k cascade fgfr3 0.8793949304987733 1.443175519376654 0.1489710338436893 1.0 0.5165111173425555 2 Q06124 1
Frs mediated fgfr3 signaling 0.8793949304987733 1.443175519376654 0.1489710338436893 1.0 0.5165111173425555 2 Q06124 1
Frs mediated fgfr2 signaling 0.8793949304987733 1.443175519376654 0.1489710338436893 1.0 0.5165111173425555 2 Q06124 1
Frs mediated fgfr4 signaling 0.8793949304987733 1.443175519376654 0.1489710338436893 1.0 0.5165111173425555 2 Q06124 1
Downstream signaling of activated fgfr3 0.8793949304987733 1.443175519376654 0.1489710338436893 1.0 0.5165111173425555 2 Q06124 1
Pi 3k cascade fgfr4 0.8793949304987733 1.443175519376654 0.1489710338436893 1.0 0.5165111173425555 2 Q06124 1
Signaling by flt3 itd and tkd mutants 0.8793949304987733 1.443175519376654 0.1489710338436893 1.0 0.5165111173425555 2 Q06124 1
Downstream signaling of activated fgfr2 0.8793949304987733 1.443175519376654 0.1489710338436893 1.0 0.5165111173425555 2 Q06124 1
Stat5 activation 0.8793949304987733 1.443175519376654 0.1489710338436893 1.0 0.5165111173425555 2 Q06124 1
Pi 3k cascade fgfr2 0.8793949304987733 1.443175519376654 0.1489710338436893 1.0 0.5165111173425555 2 Q06124 1
Frs mediated fgfr1 signaling 0.8793949304987733 1.443175519376654 0.1489710338436893 1.0 0.5165111173425555 2 Q06124 1
Rhoa gtpase cycle 0.4110525945269816 1.4276285037705738 0.1533988148489764 1.0 0.5275017245819358 37 Q15904,P61586,Q9UDY2 3
Glutathione synthesis and recycling 0.6947525548293108 1.4163266442188422 0.156679890301326 1.0 0.5311396451642934 5 Q9UJ14 1
Diseases of mitotic cell cycle 0.6052167350667489 1.395827831740294 0.1627663471270199 1.0 0.536560222411212 8 Q9UJX2,Q16763,Q9UJX4,P11802 4
Mismatch repair 0.5992741753403399 1.3678697465655942 0.1713528510520596 1.0 0.556091361523901 8 Q9UQ84,P15927 2
Fanconi anemia pathway 0.6832257093569016 1.3678152039581843 0.17136992739945 1.0 0.556091361523901 5 Q9BXW9,Q9NVI1,P15927 3
Mtor signalling 0.557010555483063 1.3657566939370482 0.1720153430927111 1.0 0.556091361523901 10 Q96B36,Q04637,Q9Y376,P23588,P54619,P06730 6
Grb2 sos provides linkage to mapk signaling for integrins 0.8601798855273918 1.365252727351581 0.1721736312363933 1.0 0.556091361523901 2 P62993 1
Clathrin mediated endocytosis 0.3853190214083308 1.356982168037741 0.1747868765461713 1.0 0.5584016159517399 42 Q9NVZ3,Q9UNS2,Q92905,P20645,Q8N6T3,O15144,P42566,P09497,P62993,Q14247,Q99961,P59998,P61201,P53680,Q14C86,Q9UBW8,P50570,Q99627,P20339,Q96D71,Q92747 21
Apc c cdc20 mediated degradation of cyclin b 0.595778124428319 1.3514088143619654 0.1765645118166143 1.0 0.5610815716487048 8 P14635,P30260,Q16763,Q9UJX2,Q9UJX4 5
Conversion from apc c cdc20 to apc c cdh1 in late anaphase 0.6384143600536978 1.336134487754362 0.1815053192902298 1.0 0.5669390530338179 6 Q9UJX2,Q16763,Q9UJX4 3
Insulin receptor signalling cascade 0.6755035216466495 1.3352773067183477 0.1817856030981628 1.0 0.5669390530338179 5 P62993,Q06124 2
Eph ephrin signaling 0.4467578386553409 1.334648801794662 0.1819913176102914 1.0 0.5669390530338179 23 P35579,P09497,P60953,P35580,O15143,O15144,P59998,P61586,P53680,Q92747 10
Semaphorin interactions 0.4972755932446082 1.3263980815826455 0.1847078739123389 1.0 0.5669390530338179 16 P35579,Q13177,P35580,O14786,Q00535,Q9Y490,P61586 7
Vxpx cargo targeting to cilium 0.6728955831002656 1.3242830891522108 0.1854090446828542 1.0 0.5669390530338179 5 Q8TAG9 1
Costimulation by the cd28 family 0.5639922543551878 1.322618027165475 0.1859624361649114 1.0 0.5669390530338179 9 P62993,Q13177,Q14738,P60953,P30153,Q06124 6
Diseases of dna repair 0.5637149625230772 1.3212535343263736 0.1864168415386151 1.0 0.5669390530338179 9 Q9UQ84,P51530 2
Protein ubiquitination 0.4516094426018969 1.3201119800403962 0.1867976335167016 1.0 0.5669390530338179 21 P61088,Q5VTR2,P68036,Q16763,P45974,P61086,Q14527,Q6PD62,Q9BUN8,A0AVT1,Q93008,Q6P1J9,P22314 13
Cellular response to heat stress 0.372109201031506 1.3191172938626516 0.1871299024134445 1.0 0.5669390530338179 51 Q96B36,P04792,Q8NFH4,P25685,P15927,Q02790 6
Negative regulators of ddx58 ifih1 signaling 0.6342100191787551 1.3177022450422482 0.18760334273147 1.0 0.5669390530338179 6 Q13526,Q96J02 2
Signaling by csf3 g csf 0.6331364910294661 1.3129944757174214 0.1891848096706261 1.0 0.5669390530338179 6 P62993,P40763,Q06124 3
Signaling by type 1 insulin like growth factor 1 receptor igf1r 0.7296440331487415 1.306274562101715 0.1914592044955982 1.0 0.5669390530338179 4 P62993,Q06124 2
Metabolism of folate and pterines 0.5857650431598457 1.3042187088681758 0.192159022719454 1.0 0.5669390530338179 8 P34896,Q9H2D1,P41440 3
Rho gtpases activate wasps and waves 0.5163467859807856 1.3040390926060248 0.1922202538207593 1.0 0.5669390530338179 13 Q9UQB8,P62993,O15143,O15144,P59998,Q92747 6
Striated muscle contraction 0.7275899449733443 1.298063945516653 0.1942653623634995 1.0 0.5669390530338179 4 Q9NYL9,P35609 2
Senescence associated secretory phenotype sasp 0.492136286861199 1.2959630530268111 0.1949882142147299 1.0 0.5669390530338179 16 P11802,Q9H9B1,Q16763,P40763,Q9UJX4,Q9UJX2,Q15418 7
Synthesis of active ubiquitin roles of e1 and e2 enzymes 0.5831354897034322 1.2918171506339269 0.196420474483022 1.0 0.5669390530338179 8 Q16763,P45974,P68036,A0AVT1,Q93008,P22314 6
Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s 0.3718662251615527 1.2911870949213595 0.1966388089283275 1.0 0.5669390530338179 49 P60228,Q7L2H7,P55884,P56537,P23588,P62861,O75822,Q9Y262,P05198,P60842,Q04637,O15372,P06730 13
Parasite infection 0.4992328589703019 1.2903713320813306 0.1969217608095932 1.0 0.5669390530338179 15 P35579,Q9UQB8,P62993,O15143,O15144,P59998,Q92747 7
Cyclin d associated events in g1 0.6081118517070411 1.2893437805776862 0.1972785968797414 1.0 0.5669390530338179 7 P63208,P63151,P11802,P30153 4
Tgf beta receptor signaling in emt epithelial to mesenchymal transition 0.8409648405560143 1.2874299794392066 0.1979444606097471 1.0 0.5669390530338179 2 P61586 1
Signaling by ntrk2 trkb 0.8482617586912029 1.28506319860381 0.1987702003750118 1.0 0.5669390530338179 3 P62993,Q06124 2
Metabolic disorders of biological oxidation enzymes 0.7231695636424782 1.280394059244642 0.200406582247242 1.0 0.5669390530338179 4 P22570 1
Small interfering rna sirna biogenesis 0.8465711855916653 1.278762279490936 0.2009807807406551 1.0 0.5669390530338179 3 Q9UPY3 1
Interleukin 20 family signaling 0.8464091682282575 1.2781584701648192 0.2011935560354523 1.0 0.5669390530338179 3 P40763 1
Interleukin 6 family signaling 0.8464091682282575 1.2781584701648192 0.2011935560354523 1.0 0.5669390530338179 3 P40763 1
Interleukin 6 signaling 0.8464091682282575 1.2781584701648192 0.2011935560354523 1.0 0.5669390530338179 3 P40763 1
Cargo concentration in the er 0.5535892010010125 1.271399070287062 0.2035867132188253 1.0 0.5669390530338179 9 Q5JRA6 1
Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants 0.8427281866331657 1.264442373981353 0.2060712918661185 1.0 0.5669390530338179 3 P40763 1
Interleukin 2 family signaling 0.8427281866331657 1.264442373981353 0.2060712918661185 1.0 0.5669390530338179 3 P40763 1
Signaling by kit in disease 0.8427281866331657 1.264442373981353 0.2060712918661185 1.0 0.5669390530338179 3 P40763 1
Processing of dna double strand break ends 0.4398206093189046 1.2617953188516415 0.207022447060893 1.0 0.5669390530338179 22 Q9UQ84,Q92547,P15927,Q9NXR7 4
Biosynthesis of specialized proresolving mediators spms 0.8414978288012439 1.2598588406492397 0.2077202889238212 1.0 0.5669390530338179 3 P34913 1
Egfr downregulation 0.7172667757774088 1.256798928022595 0.2088264543312417 1.0 0.5687829817970521 4 P62993,P42566,P60953 3
Synthesis of leukotrienes lt and eoxins ex 0.8303352412101415 1.2444637683897528 0.2133289261105462 1.0 0.5780374285204999 2 P09960 1
Inhibition of replication initiation of damaged dna by rb1 e2f1 0.617276270624559 1.243397857775358 0.2137212593146471 1.0 0.5780374285204999 6 P49642,P09884,P06400,P30153 4
Phosphorylation of the apc c 0.5475252283170537 1.2415244637909022 0.2144120665973088 1.0 0.5780374285204999 9 P14635,P30260,Q16763,Q9UJX2,Q9UJX4 5
Gpvi mediated activation cascade 0.712833614914942 1.2390805164693357 0.2153156816234895 1.0 0.57929127377725 4 P61586 1
Signaling by pdgfr in disease 0.7053722174050043 1.209267655071668 0.2265600330313324 1.0 0.597376853561657 4 P62993,P40763 2
Glycogen synthesis 0.7031395854605677 1.2003499727086169 0.2300034493438176 1.0 0.6029541042310504 4 P13807,P36871 2
Recycling of eif2 gdp 0.5884356292077368 1.2002440718817422 0.230044563612755 1.0 0.6029541042310504 7 Q9NR50,Q9UI10 2
Activation of the pre replicative complex 0.496055152053482 1.1921835149837614 0.2331892958342356 1.0 0.6087807505870065 13 P27694,P33991,P49642,Q07864,P33993,P25205,P09884,P15927 8
Intra golgi and retrograde golgi to er traffic 0.328024471303758 1.1848559246516157 0.2360744165150987 1.0 0.6138864256229241 69 O60664,P52732,Q5VZE5,P35606,Q13409,P40616,Q14203,Q9BVK6,P20645,Q8N6T3,Q9Y6G9,Q15042,P83436 13
Flt3 signaling in disease 0.6975346944035957 1.1779709427829317 0.2388081905285042 1.0 0.6197637089814686 4 P62993,Q06124 2
Interleukin 4 and interleukin 13 signaling 0.5046281236776536 1.174552503256534 0.240173795020278 1.0 0.6197637089814686 11 P04083 1
Aberrant regulation of mitotic exit in cancer due to rb1 defects 0.5804858558423871 1.1642453042153422 0.2443246152614331 1.0 0.6254899549619247 7 Q16763,Q9UJX2 2
Pkmts methylate histone lysines 0.4899813343159449 1.158704458082498 0.2465766730359671 1.0 0.6274028740842285 13 Q9H7B4,O15047 2
Mastl facilitates mitotic progression 0.6334122096750086 1.157736440327446 0.2469716082693405 1.0 0.6274028740842285 5 P14635,O43768,P30153 3
Homology directed repair 0.3938086750948204 1.1468941589805923 0.2514253670452899 1.0 0.6314313875795209 32 P41440,Q9UQ84,Q9NXR7,Q92547,P15927 5
Dna replication initiation 0.6873977086743006 1.1375358359961696 0.255314352499467 1.0 0.6320050681171466 4 P49642,P09884,Q07864 3
Esr mediated signaling 0.3856414464823914 1.1257135917531074 0.2602867687892694 1.0 0.6320050681171466 34 Q13451,Q99873,P04792,Q02790 4
Negative regulation of fgfr2 signaling 0.6255911565362676 1.1247864667733158 0.2606795305498863 1.0 0.6320050681171466 5 P62993,Q06124 2
Signaling by fgfr3 0.6255911565362676 1.1247864667733158 0.2606795305498863 1.0 0.6320050681171466 5 P62993,Q06124 2
Signaling by fgfr1 0.6255911565362676 1.1247864667733158 0.2606795305498863 1.0 0.6320050681171466 5 P62993,Q06124 2
Negative regulation of fgfr4 signaling 0.6255911565362676 1.1247864667733158 0.2606795305498863 1.0 0.6320050681171466 5 P62993,Q06124 2
Spry regulation of fgf signaling 0.6255911565362676 1.1247864667733158 0.2606795305498863 1.0 0.6320050681171466 5 P62993,Q06124 2
Negative regulation of fgfr3 signaling 0.6255911565362676 1.1247864667733158 0.2606795305498863 1.0 0.6320050681171466 5 P62993,Q06124 2
Signaling by fgfr4 0.6255911565362676 1.1247864667733158 0.2606795305498863 1.0 0.6320050681171466 5 P62993,Q06124 2
Negative regulation of fgfr1 signaling 0.6255911565362676 1.1247864667733158 0.2606795305498863 1.0 0.6320050681171466 5 P62993,Q06124 2
Pi3k akt signaling in cancer 0.5717134531574616 1.1245452029755871 0.2607818053141792 1.0 0.6320050681171466 7 Q96B36,Q06124 2
Nephrin family interactions 0.5691250803837082 1.112838884846808 0.265777631723413 1.0 0.6406792910704903 7 Q01082,P12814,Q13813,Q9Y5K6,P35609 5
Release of apoptotic factors from the mitochondria 0.7959934587080969 1.10637440123951 0.2685645006935568 1.0 0.6428843731429466 2 Q9NR28 1
Host interactions of hiv factors 0.3161503855710951 1.1050582681703724 0.2691343418107148 1.0 0.6428843731429466 88 P48556,Q13200,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,P53680,Q99436,P43487,P63208,P51665,Q9BXS5,Q93034,P20618,O43747,P17096,O43242,Q8NFH4,P60900,Q15008,Q06323,Q92530 26
Signaling by robo receptors 0.2947079394122751 1.1046495809232164 0.2693114583160452 1.0 0.6428843731429466 128 P48556,P63173,P62861,O14786,P84098,P23396,Q13200,Q13617,P61586,Q04637,P08865,P25789,P46776,P18077,Q8TEY7,Q01518,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q9UNM6,O00231,P61927,P05387,Q99436,P17612,P18124,P35998,P42766,P51665,P60953,P62191,Q7Z460,P20618,O43242,Q13177,O14818,P61513,P60900,P46777,Q15008,P83881,Q06323,Q92530,P39019 48
Energy dependent regulation of mtor by lkb1 ampk 0.679132293566194 1.1046165347880297 0.2693257833147502 1.0 0.6428843731429466 4 Q9Y376,P54619 2
Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components 0.5430792031970455 1.1028345149291074 0.2700990364075211 1.0 0.6428843731429466 8 Q16763,Q9UJX2 2
Apc cdc20 mediated degradation of nek2a 0.5430792031970455 1.1028345149291074 0.2700990364075211 1.0 0.6428843731429466 8 Q16763,Q9UJX2 2
Crmps in sema3a signaling 0.6770215521732645 1.0962188213227142 0.2729830248936937 1.0 0.6485801724542616 4 O14786,Q00535 2
Regulation of hsf1 mediated heat shock response 0.3552679118236659 1.0943849275206403 0.2737861916213402 1.0 0.6493205729475592 45 P04792,Q8NFH4,P25685,P15927,Q02790 5
Signaling by ntrk3 trkc 0.7963190184048949 1.0921755946418803 0.274755927463326 1.0 0.6499580217614204 3 P62993,Q8WX92 2
Fgfr1 mutant receptor activation 0.5797798189189116 1.0789302285974651 0.2806188320755343 1.0 0.6579423839696507 6 O95684,P40763 2
Signaling by fgfr1 in disease 0.5797798189189116 1.0789302285974651 0.2806188320755343 1.0 0.6579423839696507 6 O95684,P40763 2
Gastrin creb signalling pathway via pkc and mapk 0.6137562674659104 1.0750050643140594 0.2823724609794018 1.0 0.6584354252510318 5 P62993 1
Purine salvage 0.6706887065601022 1.0710483933449757 0.2841476707082597 1.0 0.6608434383901605 4 P55263 1
Sema3a plexin repulsion signaling by inhibiting integrin adhesion 0.7833197056418666 1.0558174314178426 0.2910516327642436 1.0 0.6660950455963945 2 Q9Y490 1
Irs mediated signalling 0.7852760736196234 1.051475096185056 0.2930404414016205 1.0 0.6662761154759738 3 P62993,Q06124 2
Transcriptional regulation of white adipocyte differentiation 0.5732007059339634 1.0501578906213835 0.2936455263010624 1.0 0.6665047083225145 6 P11802,Q86X55,Q9ULK4 3
Apoptotic factor mediated response 0.603292679185827 1.031102702856788 0.3024926604573628 1.0 0.6818989837272632 5 Q9NR28 1
Egr2 and sox10 mediated initiation of schwann cell myelination 0.5650817417772648 1.014717846844951 0.3102403443396646 1.0 0.693363216731988 6 Q9NR77 1
Cd28 co stimulation 0.6562162517499568 1.0136967034144784 0.3107274975816327 1.0 0.693363216731988 4 P62993,P60953 2
Metabolism of nucleotides 0.3552517335911198 1.0049121105174508 0.3149391724282195 1.0 0.6993149824016188 39 Q9H773,Q9NRF8,P55263 3
Prolactin receptor signaling 0.772079238258524 1.0030547265270493 0.3158344569920144 1.0 0.6993149824016188 3 Q06124 1
Transcriptional regulation by ventx 0.4718823454358058 1.0021268100774725 0.3162823508226533 1.0 0.6993149824016188 11 Q9UJX2,Q16763,Q9UJX4 3
Dna double strand break repair 0.3464347807897338 1.00006586589008 0.3172786336783719 1.0 0.6997079717681625 43 P41440,Q9UQ84,Q04323,Q9NXR7,Q92547,P15927 6
Muscle contraction 0.4059978075867929 0.9946617200492508 0.3199008182609417 1.0 0.7024006893682277 20 Q9NYL9,P30626,Q05682,P04083,Q13177,Q9Y490,P08670,P35609 8
Mapk3 erk1 activation 0.6469377486415785 0.9770815281540036 0.3285287918210029 1.0 0.7126215664951475 4 P06493,Q06124 2
Diseases of mismatch repair mmr 0.762469337694198 0.9733168030301992 0.3303958737801471 1.0 0.7154966381370071 2 P43246 1
Creb1 phosphorylation through nmda receptor mediated activation of ras signaling 0.5864119465607752 0.960586171848804 0.3367602842834465 1.0 0.7218613109574238 5 P35609 1
Trna modification in the nucleus and cytosol 0.4754253139251259 0.9510234371888172 0.3415924784547739 1.0 0.7289881486894287 10 O75648,Q9NWX6,P57081 3
E2f mediated regulation of dna replication 0.4834635674585289 0.9271766635222332 0.35383481715172 1.0 0.743109369566649 9 P14635,P06493,P49642,P06400,P09884,P30153 6
Mtorc1 mediated signalling 0.501377052616897 0.9075577585384582 0.3641119205293512 1.0 0.7517019536462051 8 Q96B36,P23588,Q04637,P06730 4
Cd28 dependent vav1 pathway 0.7456032719836443 0.9068313518030436 0.3644959878158766 1.0 0.7517019536462051 3 P62993,P60953 2
Hdms demethylate histones 0.5401550965895551 0.9065668759010808 0.3646358849147852 1.0 0.7517019536462051 6 Q8NB78 1
Flt3 signaling 0.7451696128637653 0.9052674139767404 0.3653237352315395 1.0 0.7517019536462051 3 Q06124 1
Gab1 signalosome 0.7451696128637653 0.9052674139767404 0.3653237352315395 1.0 0.7517019536462051 3 Q06124 1
Signaling by ptk6 0.5226834213436645 0.9041422698653432 0.3659199670912283 1.0 0.7517578173056183 7 P11802,P61586,P40763 3
Ub specific processing proteases 0.3095097735697912 0.8981533734491692 0.3691037873841121 1.0 0.7559474467200187 64 P48556,Q13200,P25789,Q8TEY7,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,O00231,Q99436,P51665,P20618,Q86UV5,O43242,P60900,Q15008,Q06323,Q92530 21
Sema3a pak dependent axon repulsion 0.5696207652778992 0.8909656253540051 0.3729476117186907 1.0 0.7602836343833186 5 O14786 1
E3 ubiquitin ligases ubiquitinate target proteins 0.4352913530535989 0.8889776729454462 0.3740150792110763 1.0 0.7603422686035899 14 Q6PD62 1
The role of nef in hiv 1 replication and disease pathogenesis 0.4490377198279709 0.8830333207756872 0.3772182686534939 1.0 0.7603422686035899 11 Q10567,Q13177,Q9BXS5,P53680,O43747 5
Deadenylation of mrna 0.4488983898093517 0.8823119368654366 0.3776081430482203 1.0 0.7603422686035899 11 Q9C0C2,P23588,Q04637,Q92600,P06730 5
Ngf stimulated transcription 0.7385076025058864 0.8812979018680347 0.378156601417531 1.0 0.7603422686035899 3 Q00535 1
Dna strand elongation 0.3841872322346638 0.8796287630251278 0.3790604518454408 1.0 0.7610013022611357 22 P27694,P33991,P41440,P49642,P51530,P39748,Q9BRT9,P33993,P25205,P09884,P15927 11
Regulation of tp53 activity 0.33325659223627 0.8781231245524264 0.3798769049574273 1.0 0.7614831433213376 43 Q9H9B1,Q9UQ84,P51530,Q13526,Q8WXI9,O14744,Q92547,Q92804,P15927 9
Signaling by erbb4 0.564835067605683 0.8712431690681803 0.3836213935938739 1.0 0.7666624219932034 5 P62993,Q96J02,P16949 3
Unwinding of dna 0.5120187468073485 0.856824461476347 0.3915419046945341 1.0 0.7746453246045926 7 Q9BRT9,P33993,P33991 3
Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand 0.362814673097151 0.8552916313392487 0.3923897193118879 1.0 0.7746453246045926 29 P31948,Q13409,Q13451,Q14203,Q9Y6G9,Q9UJW0,Q9BUF5,P25685,P54652,O43237,Q02790 11
Cargo recognition for clathrin mediated endocytosis 0.3653695324698103 0.852462791031252 0.3939572824209048 1.0 0.7746453246045926 27 Q99627,Q9NVZ3,P42566,Q9UNS2,P62993,Q9UBW8,P20645 7
Translesion synthesis by polk 0.4889911141503258 0.8502987873445578 0.395158990608432 1.0 0.7746453246045926 8 P41440 1
Regulation of expression of slits and robos 0.2731626111166759 0.8493910987700274 0.3956637045237237 1.0 0.7746453246045926 118 P48556,P63173,P62861,P84098,Q13200,Q04637,P25789,Q8TEY7,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,P61927,P05387,Q99436,P51665,P20618,O43242,P60900,P46777,Q15008,P83881,Q06323,Q92530 27
Regulation of tp53 activity through phosphorylation 0.364798706505107 0.8482553528408419 0.3962957764015264 1.0 0.7746453246045926 27 Q9UQ84,Q13526,Q92547,Q92804,P15927 5
Endosomal sorting complex required for transport escrt 0.5240334238396652 0.8373686604546986 0.4023853760411615 1.0 0.7776784747050048 6 Q99816,O43633 2
Sphingolipid de novo biosynthesis 0.4521408180225646 0.8345616342454732 0.403964571192114 1.0 0.7790324066347192 10 Q06136 1
Extracellular matrix organization 0.3686705866208207 0.8288914525109228 0.4071658324720739 1.0 0.7793032103922602 25 Q9Y624,P20810,P11047,P07384,P35613,O60568,P17655,O75718,O15460 9
Ros and rns production in phagocytes 0.5041146645735677 0.8219768787973456 0.4110900561720139 1.0 0.7813166021210639 7 P21281,Q9Y487,Q93050,Q9UI12 4
Collagen biosynthesis and modifying enzymes 0.4369979127689841 0.8209845375585334 0.4116550757579564 1.0 0.7813166021210639 11 O60568,O15460 2
Nef mediated downregulation of mhc class i complex cell surface expression 0.6033822949750338 0.8075962668683699 0.4193230364841362 1.0 0.7889106101673016 4 Q9BXS5,O43747 2
Dna damage recognition in gg ner 0.4203333143454531 0.806704748267886 0.4198366078331665 1.0 0.7889106101673016 14 Q99627,Q9UNS2,Q9UBW8,Q92905,P54727,P61201 6
Ret signaling 0.7104294478527456 0.7816011866352627 0.4344489893083867 1.0 0.794221008196557 3 P62993,Q06124 2
Recruitment of mitotic centrosome proteins and complexes 0.3669208779985218 0.7790137927277709 0.4359715899249701 1.0 0.794221008196557 23 P06493,P61981,P17612,Q13409,Q14203,O95684,Q15691,O75935,P68371,Q7Z460,P30153 11
Regulation of glycolysis by fructose 2 6 bisphosphate metabolism 0.5957446808510591 0.7784215843903906 0.4363205182457736 1.0 0.794221008196557 4 Q14738,P30153,P17612 3
Ctla4 inhibitory signaling 0.59574468085105 0.7784215843903551 0.4363205182457945 1.0 0.794221008196557 4 Q14738,P30153,Q06124 3
G2 m dna damage checkpoint 0.3509949185617957 0.7783762353929687 0.4363472444438208 1.0 0.794221008196557 30 Q9UQ84,Q92547,P15927,Q9NXR7 4
Formation of incision complex in gg ner 0.4728237591581379 0.7763692248441668 0.4375310102593766 1.0 0.794221008196557 8 P27694,P15927,P54727 3
G2 m dna replication checkpoint 0.7109566639411329 0.7747193510132151 0.4385055138746008 1.0 0.794221008196557 2 P14635 1
Chromatin modifying enzymes 0.3083091417473454 0.7738663734420886 0.4390098168201866 1.0 0.794221008196557 58 P11802,Q9H9B1,Q9Y2K7,P61964,Q8NB78,Q8WXI9,Q99873,Q12824,O14744,Q9H7B4,O60678,O15047,Q15014 13
Dna repair 0.2910596690068223 0.772714472182334 0.4396913798349642 1.0 0.794221008196557 85 Q99627,P27695,P41440,Q6P6C2,Q9UQ84,Q9UBW8,P51530,Q04323,Q9BXW9,Q9NXR7,Q9C0B1,P54727,Q92547,P43246,Q9NVI1,P15927 16
Cd209 dc sign signaling 0.710139002452989 0.771645518810811 0.4403244067535823 1.0 0.794221008196557 2 Q13177 1
Response of eif2ak1 hri to heme deficiency 0.707438739610428 0.7711265627671104 0.4406319173714217 1.0 0.794221008196557 3 P05198 1
Interleukin 3 interleukin 5 and gm csf signaling 0.5398001017858347 0.7691889078562573 0.4417811742582207 1.0 0.794221008196557 5 P62993,P17612,Q06124 3
Lipophagy 0.7041701305026373 0.7597142587151854 0.4474254037904535 1.0 0.8008793474352155 3 O60664 1
P75ntr regulates axonogenesis 0.7007340820347225 0.747758751967323 0.454605686116452 1.0 0.8060860555165547 3 P61586 1
Rhoc gtpase cycle 0.3569868957575023 0.7467117074594585 0.4552376012500101 1.0 0.8061244922939188 25 P61586,Q9UDY2 2
Mitochondrial biogenesis 0.348706074165767 0.739439521636109 0.4596401511063512 1.0 0.8117441706035963 28 P48735 1
Er to golgi anterograde transport 0.2995239100689196 0.7316454427322334 0.4643850040731156 1.0 0.816847656964828 61 Q14789,Q92734,Q14203,Q8N6T3,Q9Y6G9,Q5JRA6,O60763,Q9UJW0,Q9Y296,O43237,P35606,P18085,O95486,P49257,O75935,Q9BUF5,P68371,P83436,P61923,Q5H9R7,Q13409,Q9UBF2,Q9Y678,Q9BVK6,Q15436,P53621 26
Signaling by tgfb family members 0.3794378894609422 0.7189702523393011 0.4721592487714758 1.0 0.8238732245721708 18 Q7Z3T8,Q9Y624,Q9UPN9,Q9Y5K5,P61081,P61586,Q9Y3F4 7
Signaling by met 0.4087170083949236 0.7184814225515597 0.4724604984972129 1.0 0.8238732245721708 13 P42566,P62993,P11047,P40763,Q06124 5
Cholesterol biosynthesis 0.4081502493932363 0.7155165830951496 0.4742898976280048 1.0 0.8238732245721708 13 Q15392 1
Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1 0.6946034341782552 0.713824681665023 0.4753355955554785 1.0 0.8238732245721708 2 P06493 1
Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters 0.4264856235427641 0.708946169048679 0.4783578828515178 1.0 0.8238732245721708 10 Q9BXS5,O43747,P53680,Q10567 4
Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 0.6913327882256797 0.701801671081781 0.4828028564997417 1.0 0.8293661553136006 2 P11802 1
Pentose phosphate pathway 0.4757821268318845 0.6990819814922747 0.4845007983930722 1.0 0.8301239360275596 7 Q96G03,P11413,O95336 3
Collagen formation 0.4039042736568709 0.6933813938708883 0.4880702355677413 1.0 0.8331869663652167 13 O60568,O15460 2
Integrin cell surface interactions 0.6848731889836521 0.6931629183207475 0.488207316241863 1.0 0.8331869663652167 3 P35613 1
Nervous system development 0.2858232970858424 0.6806588265983713 0.4960873947106434 1.0 0.8404644150149394 190 P48556,P63173,P62861,O14786,O15144,P84098,O15143,Q13200,P61586,Q04637,P25789,Q06124,P35579,Q8TEY7,P09497,Q01518,P62993,P25787,P49721,P35241,Q99460,P28072,P28074,Q9UL46,P28070,P59998,Q00169,Q9NR77,P53680,P61927,O95372,P05387,P15311,Q99436,P51665,Q9BUF5,Q9Y490,P50570,P20618,Q96S59,O43242,P11047,P60900,Q00535,P46777,Q15008,Q15418,P83881,Q06323,Q92530,Q92747 51
Membrane trafficking 0.28484891559141 0.680300607985506 0.4963141396503558 1.0 0.8404644150149394 184 Q14789,Q9NVZ3,O43633,O60664,Q92734,Q9UNS2,Q14203,P20645,O60749,Q8N6T3,P55327,Q9Y6G9,O15144,P11233,Q5JRA6,P33176,P35579,P42566,Q5VZE5,P09497,Q8TAG9,Q04917,O60343,Q14247,P40616,P62993,Q8IWJ2,Q9Y5X3,Q9UJW0,Q9Y296,P59998,P61201,P54619,Q8TC07,P53680,O43237,P52732,P35606,P18085,Q99816,Q9UBW8,Q9BUF5,Q15042,Q9UIQ6,Q9BXS5,P50570,P83436,O43747,Q99627,Q13409,P20339,Q9UN37,Q9BVK6,O00471,Q15436,Q92747 56
Rora activates gene expression 0.6852003270646007 0.6794098939921792 0.4968781826162307 1.0 0.8404644150149394 2 Q86X55 1
Fceri mediated mapk activation 0.5685392407686909 0.6763281057928521 0.4988323520393782 1.0 0.8404644150149394 4 P62993 1
Raf independent mapk1 3 activation 0.516383671835548 0.6759238744276056 0.4990889788335426 1.0 0.8404644150149394 5 P06493,Q06124 2
Budding and maturation of hiv virion 0.4696167021711233 0.6728540316998882 0.5010401592570144 1.0 0.8404644150149394 7 Q99816,O43633,Q9UN37 3
Eukaryotic translation initiation 0.2742859199756823 0.6646465543969137 0.506276585356779 1.0 0.8404644150149394 99 P60228,Q7L2H7,P63173,P62861,O75822,P84098,Q04637,P56537,P23588,Q9Y262,P61927,P55010,P05387,P06730,P55884,P05198,P60842,O15372,Q9UI10,Q9NR50,P61513,P46777,P83881 23
Regulation of runx1 expression and activity 0.6763782100671858 0.6643568110141135 0.50646196818832 1.0 0.8404644150149394 3 Q06124 1
Er quality control compartment erqc 0.6798855273916655 0.6601704350690502 0.5091444626053903 1.0 0.8428318735610533 2 Q9UBV2 1
Caspase mediated cleavage of cytoskeletal proteins 0.5638669366245173 0.6591272628994334 0.509814050093029 1.0 0.8428840552852207 4 P08670,Q15149 2
Runx1 regulates transcription of genes involved in differentiation of myeloid cells 0.6786590351594497 0.6557533622065941 0.5119828284641268 1.0 0.8454116455013894 2 P17931 1
Fcgamma receptor fcgr dependent phagocytosis 0.3584189323504041 0.637101316149896 0.5240588513221982 1.0 0.8578460255224584 19 P35579,Q9UQB8,P62993,O15143,O15144,P59998,Q92747 7
Cell surface interactions at the vascular wall 0.3993390952891673 0.6321087702154817 0.5273158047711577 1.0 0.8618389332743024 11 P62993,P14174,Q06124,P35613 4
Translocation of slc2a4 glut4 to the plasma membrane 0.3426232779196144 0.6313633866045762 0.5278029500521655 1.0 0.8618389332743024 24 P35579,Q8TAG9,O60343,Q04917,O00471,Q9BUF5,Q9UIQ6,P11233 8
Uptake and function of anthrax toxins 0.6700735895339387 0.6250836922692149 0.5319161304617945 1.0 0.8653463156896929 2 Q8WUM4 1
Map2k and mapk activation 0.4185233891881182 0.6207181261151794 0.5347851010174638 1.0 0.8657489196618501 9 Q02750,P18206,Q9Y490,P41240,P30086 5
Nucleotide biosynthesis 0.392561477260663 0.6156187989376701 0.538146141047859 1.0 0.866812362810021 12 P22102,P49915,P30520,Q05682,P11172,O15067,P30566,P27708 8
Translesion synthesis by polh 0.3918319282468271 0.5957445784482053 0.551345872862322 1.0 0.8743432149473317 11 P41440 1
Erks are inactivated 0.4503759241250951 0.5925041002343578 0.553513075902816 1.0 0.8754145017890027 7 P51452,Q14738,P30153,Q8IV63 4
Downregulation of smad2 3 smad4 transcriptional activity 0.4895096294711563 0.5724516605792029 0.5670160256571919 1.0 0.8871826194868945 5 Q9UPN9,Q13547 2
Signaling by tgf beta receptor complex 0.3606493706710346 0.5717352157759962 0.5675013727982028 1.0 0.8871826194868945 17 Q9Y624,Q9UPN9,Q9Y5K5,P61081,P61586,Q9Y3F4 6
Signaling by flt3 fusion proteins 0.6475847367081176 0.5693515847804522 0.5691175660756933 1.0 0.8879852155404889 3 P62993 1
Runx1 regulates genes involved in megakaryocyte differentiation and platelet function 0.3828624257908776 0.568062733520937 0.569992371324 1.0 0.8879852155404889 12 O15047,P61964 2
Cytosolic sulfonation of small molecules 0.6448116414817812 0.5604406060293753 0.5751789411199439 1.0 0.8937089934704197 3 O95861 1
Pd 1 signaling 0.6492232215862699 0.5525793847826921 0.5805514615468548 1.0 0.8954857097891481 2 Q06124 1
Regulated necrosis 0.3690973386569208 0.5370208988332836 0.591253178244497 1.0 0.8981972001823538 14 P41440 1
Cyclin a b1 b2 associated events during g2 m transition 0.4350390563783298 0.5303779515420739 0.5958499098404091 1.0 0.9020820130052888 7 P14635,P63151,P30153 3
Anchoring of the basal body to the plasma membrane 0.3263591392313681 0.5134397087341037 0.6076437749379129 1.0 0.9100877853661936 23 P06493,P61981,P17612,Q13409,Q14203,O95684,Q15691,O75935,P68371,Q7Z460,P30153 11
Late endosomal microautophagy 0.4297851954562314 0.5095499890335108 0.610366768338996 1.0 0.9118516098904078 7 O60664,O43633,Q99816 3
Biological oxidations 0.2972591676768883 0.5088002281612961 0.6108922594648076 1.0 0.9118516098904078 39 Q99707,P22570,P30837,P28161,Q969Z3 5
Rhou gtpase cycle 0.367594683559335 0.495332215423407 0.6203656341229322 1.0 0.9170436220408344 12 Q01082,P62993,Q13813,O43396,Q13177,P60953,Q93008,P46940 8
Rhof gtpase cycle 0.356145441352842 0.4930921826722996 0.6219474541932397 1.0 0.9170436220408344 15 Q02952 1
Rho gtpases activate paks 0.4057989854963943 0.4863111856099653 0.6267465497363949 1.0 0.9170436220408344 8 P35579,P35580,Q14247,P60953 4
Non integrin membrane ecm interactions 0.5147457128982507 0.4860710873276158 0.6269167653730632 1.0 0.9170436220408344 4 P11047,Q9Y296 2
Ncam signaling for neurite out growth 0.4634678084562124 0.4769641016252804 0.6333876846059809 1.0 0.9193346602356356 5 P62993,Q13813 2
M phase 0.2654964850863905 0.476104535812839 0.6339999057340377 1.0 0.9193346602356356 161 O43633,Q92530,Q92973,Q16763,Q14203,P48556,Q9Y6G9,Q9UJX4,Q13200,P63151,O43264,O43683,O60763,P25789,Q01105,P30260,O43768,P25787,P49721,Q15021,Q99460,P28072,P28074,Q9UL46,P28070,Q9UNM6,O00231,O43237,Q14974,P14635,Q99436,P06493,Q9Y2U8,P17612,P35998,P51665,O75935,Q9NTJ3,Q86XL3,Q9BUF5,P68371,Q9Y266,P62191,Q9P258,Q7Z460,P20618,Q13409,Q8N3U4,O95684,O43242,Q9UN37,Q15691,Q8NFH4,Q9UJX2,P60900,Q15008,Q06323,P30153 58
Global genome nucleotide excision repair gg ner 0.3100960339073345 0.4737137818953765 0.635704024068614 1.0 0.9197864357005904 29 Q99627,P41440,Q9UBW8,P54727,P15927 5
Lagging strand synthesis 0.3517987478082187 0.4714789236381959 0.6372987671341968 1.0 0.9203059719887116 15 P41440,P49642,P51530,P39748,P09884,P15927 6
Processive synthesis on the lagging strand 0.3713979127686349 0.4562468282103531 0.6482124948389667 1.0 0.9291925305723644 10 P27694,P49642,P51530,P39748,P09884,P15927 6
Negative regulation of mapk pathway 0.3780237802378096 0.4453364542281375 0.6560766272602838 1.0 0.932914127675818 9 P27361,P53041,Q02750,P31946,P30086,Q14738,P30153,P30154 8
Rmts methylate histone arginines 0.3184184237500535 0.4428536982701691 0.6578715598007874 1.0 0.9344605704267098 20 P61964,Q99873,Q12824,O14744,P11802,O60678 6
Map3k8 tpl2 dependent mapk1 3 activation 0.6045946228624838 0.4368454122890178 0.6622234624145944 1.0 0.93761757111434 3 P63208 1
Runx2 regulates bone development 0.4496357161661193 0.4286052869205956 0.6682104973808616 1.0 0.9410512441792304 5 Q96PK6,P06400 2
Maturation of sars cov 2 nucleoprotein 0.4466773838723228 0.4185024033192279 0.675579829759795 1.0 0.949405271396478 5 Q99873,P78362 2
Tp53 regulates transcription of dna repair genes 0.3124838846268775 0.4144036248648328 0.6785785346843622 1.0 0.9520408376796112 21 Q8WX92,Q9BXW9,Q9H3P2,Q08945,O00267,Q9NYV4,P43246,Q9NVI1 8
Metabolism of water soluble vitamins and cofactors 0.3000855320133503 0.4131087673060879 0.6795269262580557 1.0 0.9520408376796112 30 Q99707,P43490,P34896,P41440 4
Inactivation of csf3 g csf signaling 0.492157352209889 0.4124742594569825 0.6799918437133312 1.0 0.9520408376796112 4 P40763 1
Pp2a mediated dephosphorylation of key metabolic factors 0.5955010224948872 0.4105407715852204 0.6814093013350262 1.0 0.9520408376796112 3 Q14738,P30153 2
Rhob gtpase cycle 0.3299099725094927 0.4094930695128547 0.6821778517895773 1.0 0.9520408376796112 17 Q9UDY2 1
Signaling by ctnnb1 phospho site mutants 0.4160524160524287 0.4080719831721747 0.6832208282515302 1.0 0.9520408376796112 6 P49841,Q14738,P48729,P30153,P30154 5
Beta catenin phosphorylation cascade 0.4160524160524287 0.4080719831721747 0.6832208282515302 1.0 0.9520408376796112 6 P49841,Q14738,P48729,P30153,P30154 5
Disassembly of the destruction complex and recruitment of axin to the membrane 0.4160524160524287 0.4080719831721747 0.6832208282515302 1.0 0.9520408376796112 6 P49841,Q14738,P48729,P30153,P30154 5
Mitotic spindle checkpoint 0.2779106910485063 0.3963111602982683 0.691875495125958 1.0 0.9589461004414792 41 P30260,Q13409,Q16763,P30153,Q9P258,Q15691,Q9Y6G9,Q9UJX4,Q9Y266,Q8NFH4,Q9UJX2,O43264,O43683,Q7Z460,O43237 15
Vesicle mediated transport 0.2668371377971625 0.3924718217568704 0.6947096276476121 1.0 0.9589461004414792 191 Q14789,Q9NVZ3,O43633,O60664,Q92734,Q9UNS2,Q14203,P20645,O60749,Q8N6T3,P55327,Q9Y6G9,O15144,P11233,Q5JRA6,P33176,P35579,P42566,Q5VZE5,P09497,Q8TAG9,Q04917,O60343,Q14247,P40616,P62993,Q8IWJ2,Q9Y5X3,Q9UJW0,Q9Y296,P59998,P61201,P54619,Q8TC07,P53680,O43237,P52732,P35606,P18085,Q99816,Q9UBW8,Q9BUF5,Q15042,Q9UIQ6,Q9BXS5,P50570,P83436,O43747,Q99627,Q13409,P20339,Q9UN37,Q9BVK6,O00471,Q15436,Q92747 56
Pcna dependent long patch base excision repair 0.3409567865883837 0.3877768646481001 0.6981811678027288 1.0 0.9607263777785464 13 P27695,P41440,P39748,Q07864,P15927 5
Condensation of prometaphase chromosomes 0.3616000007308699 0.3797485351556435 0.7041320883735089 1.0 0.9635491168671044 9 P14635,P06493,Q15021,Q9NTJ3,O95347,Q9BPX3 6
Metabolism of steroids 0.2866743464390202 0.3789020506793399 0.7047606013317804 1.0 0.9635491168671044 36 Q15436,P22570,Q15392,P38435 4
Runx3 regulates p14 arf 0.5944399018806295 0.3785461356443321 0.7050249277336327 1.0 0.9635491168671044 2 Q13951 1
Phase i functionalization of compounds 0.3322598871537896 0.3782313610598235 0.7052587301535369 1.0 0.9635491168671044 15 P30837 1
Assembly of collagen fibrils and other multimeric structures 0.5936222403924857 0.376161016842525 0.706797194734462 1.0 0.9635491168671044 2 Q15149 1
Type i hemidesmosome assembly 0.5936222403924857 0.376161016842525 0.706797194734462 1.0 0.9635491168671044 2 Q15149 1
Interferon signaling 0.2672580410209626 0.3706069914653209 0.7109302739089869 1.0 0.9654205255415452 57 Q9Y4X5,Q13526,Q8NFH4,P19474,Q13325,Q04637 6
Gap junction degradation 0.4052079015454164 0.3703882317718844 0.711093240993129 1.0 0.9654205255415452 6 P09497 1
Formation of rna pol ii elongation complex 0.3049453192560094 0.3681767636529627 0.7127414352386852 1.0 0.965449382592097 20 Q8WX92 1
Apoptotic cleavage of cellular proteins 0.3245821864505098 0.3603881554879395 0.7185568829440565 1.0 0.965449382592097 16 Q9UDY2 1
Signaling by alk in cancer 0.2904516912553926 0.3565574169796381 0.7214231610239215 1.0 0.965449382592097 31 P35579,Q86WB0,Q92734,Q9P2E9,P62993,P10644,Q14203,P63208,P26038,Q9HC35,Q8IWJ2,P18206,Q07866,P40763,P33176 15
Serine biosynthesis 0.5854456255110467 0.3526956340589757 0.724316632809999 1.0 0.965449382592097 2 O43175 1
Transcriptional regulation by tp53 0.2507634334473429 0.3523241956923915 0.7245951444819252 1.0 0.965449382592097 95 Q9C0C2,Q9UQ84,P51530,Q9H3P2,Q99873,Q92547,P43246,O00267,Q92600,Q04917,Q86X55,Q13526,Q8WX92,P54619,P30876,Q9H9B1,Q08945,Q9NQ88,Q9NYV4,O95983,P11413,Q8WXI9,Q9BXW9,Q07812,Q00535,O14744,Q9NVI1,Q92804,P15927 29
Platelet aggregation plug formation 0.472103649732524 0.3511160101370408 0.7255013173131417 1.0 0.965449382592097 4 P62993 1
Integrin signaling 0.472103649732524 0.3511160101370408 0.7255013173131417 1.0 0.965449382592097 4 P62993 1
N glycan trimming in the er and calnexin calreticulin cycle 0.3293321595360099 0.3500162540134872 0.7263264993601404 1.0 0.965449382592097 14 Q9BUN8,Q9UBV2,P54727,Q04323 4
Cooperation of prefoldin and tric cct in actin and tubulin folding 0.321986251782076 0.348420888029929 0.7275241177573748 1.0 0.965449382592097 16 P61758,Q9BUF5,O15212,Q99471 4
Glutathione conjugation 0.3318387747025641 0.348341895343704 0.7275834337594347 1.0 0.965449382592097 13 Q9UJ14,P28161 2
Transcriptional regulation by mecp2 0.3357674535222597 0.3456470154244916 0.7296080080501426 1.0 0.965449382592097 11 Q14353 1
Tbc rabgaps 0.3442398899889778 0.3451096514691304 0.7300119378749137 1.0 0.965449382592097 10 Q8TC07 1
Rhobtb1 gtpase cycle 0.305272055317323 0.3395740755919232 0.7341773038797026 1.0 0.9688793390860012 19 Q5VTR2,Q7Z6E9,O43396,Q8N684,P61201,P08670 6
Gp1b ix v activation signalling 0.5793131643499678 0.3355683106097192 0.7371964240929316 1.0 0.9718926908450726 2 P63104 1
Constitutive signaling by aberrant pi3k in cancer 0.465798929576745 0.3326862080114417 0.7393711614976879 1.0 0.9733264604997132 4 Q06124 1
Cell cell communication 0.2943755539027148 0.3197213890811369 0.7491795440522466 1.0 0.9769998337092732 22 Q01082,Q03001,Q9Y624,P21333,P62993,P12814,Q13813,P35221,Q14315,Q15149,Q9Y5K6,P46940,P35609,Q06124 14
Transcriptional activity of smad2 smad3 smad4 heterotrimer 0.3777140516181808 0.3191195202166916 0.7496358819362452 1.0 0.9769998337092732 7 P27361,Q13573,Q9UPN9,Q13547,P09874,Q93008 6
Aryl hydrocarbon receptor signalling 0.5578498081762395 0.3092588914336527 0.7571245990658719 1.0 0.9801833480711803 3 Q15185 1
Pi metabolism 0.3584806832533857 0.3086562306996918 0.757583041923297 1.0 0.9801833480711803 8 P20339,Q9UBF8,Q99570 3
Cytosolic trna aminoacylation 0.2895434003326381 0.2990949103681252 0.7648676295797041 1.0 0.9828697847031024 23 P26639,O43776,Q13155,P26640,P41252,Q15046,Q15181,P07814,P49588,P49591,P54577,O43324,P23381 13
Deadenylation dependent mrna decay 0.2809738649306214 0.2919924401362024 0.7702924041277797 1.0 0.986960490642868 30 Q9C0C2,P26196,P62312,P23588,Q9Y2L1,Q04637,Q92600,Q969T7,P06730 9
G1 s specific transcription 0.3522055814791662 0.2875219699671391 0.7737126821880662 1.0 0.9894234783837712 8 P09884,P31350,P06493,P00374 4
Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex 0.3344408698804079 0.2804233603662169 0.7791527167481695 1.0 0.9946608993086428 9 P14635,P06493,P63104,Q04917 4
Glycogen metabolism 0.3497913317560623 0.279564259231827 0.7798118310733861 1.0 0.9946608993086428 8 P13807,Q96G03,P36871 3
Hats acetylate histones 0.3017048538115741 0.2770218966575958 0.7817632927632572 1.0 0.9949029958962068 17 Q15014 1
Transport to the golgi and subsequent modification 0.250357012883792 0.2746765758953517 0.7835647289227812 1.0 0.9950080521251338 62 Q14789,Q92734,Q14203,Q8N6T3,Q9Y6G9,Q5JRA6,O60763,Q9UJW0,Q9Y296,O43237,P35606,P18085,O95486,P49257,O75935,Q9BUF5,P68371,P83436,P61923,Q5H9R7,Q13409,Q9UBF2,Q9Y678,Q9BVK6,Q15436,P53621 26
Regulation of tp53 activity through acetylation 0.3231980135686477 0.2675357454965995 0.7890566959034206 1.0 0.9952410428005212 10 Q8WXI9,Q13526 2
Developmental biology 0.2608735395871083 0.264102854264971 0.7917006645714819 1.0 0.9952410428005212 226 Q9Y2W1,P48556,P63173,P62861,O14786,O15144,P84098,O15143,Q13200,P61586,Q04637,P25789,Q92600,Q06124,P35579,Q8TEY7,P09497,Q01518,P62993,O60271,P25787,P49721,P35241,Q86X55,Q99460,P28072,P28074,Q9UL46,P28070,P59998,Q00169,Q9NR77,P30876,P53680,P61927,O95372,P05387,P15311,Q99436,P61964,P07384,P51665,Q9BUF5,Q9Y490,P50570,P20618,Q15008,Q96S59,Q15418,O43242,P11047,P40763,P60900,Q00535,Q9ULK4,P46777,P11802,P83881,Q06323,Q92530,Q92747 61
Interferon alpha beta signaling 0.3213681636431802 0.2611911386404553 0.7939451113460558 1.0 0.9952410428005212 10 Q13325 1
Regulation of plk1 activity at g2 m transition 0.2769248727923466 0.2606676586149833 0.7943488086845383 1.0 0.9952410428005212 27 P14635,P06493,Q13409,P17612,P63208,Q14203,O95684,Q15691,O75935,P68371,P30153 11
Met activates ptpn11 0.5350424401718429 0.2545867550999088 0.7990422900825043 1.0 0.9952410428005212 3 Q06124 1
Slc transporter disorders 0.2741145819610662 0.251615889735917 0.8013379754687677 1.0 0.9967678583749926 30 O00400,P35613 2
Condensation of prophase chromosomes 0.3161388449050847 0.2434366381169711 0.8076671641801012 1.0 0.998057507798323 10 P14635,P06493,Q9NTJ3,P06400,O95347,Q01105 6
Transcription of the hiv genome 0.2937225118127985 0.2431183359297107 0.8079137272645676 1.0 0.998057507798323 17 Q8WX92,Q08945,Q9H3P2,O00267,Q92804 5
Signaling by nuclear receptors 0.2566276645562705 0.2392148019806231 0.810939025497498 1.0 0.998682843366989 47 Q13451,P04792,Q8NB78,Q99873,Q02790 5
Phase ii conjugation of compounds 0.2767738404541437 0.233702396580762 0.8152160270706199 1.0 1.0 23 Q9UJ14,Q99707,P48506,O95861,P28161 5
Purine ribonucleoside monophosphate biosynthesis 0.3198031980319882 0.2323701031112152 0.8162505677093421 1.0 1.0 9 P22102,P49915,P30520,P12268,P22234,Q06203,O15067,P30566 8
Termination of translesion dna synthesis 0.3011059641918353 0.2280621427808903 0.8195979302495178 1.0 1.0 13 Q14258,Q07864,P15927,P41440 4
Met promotes cell motility 0.3590923280098258 0.2275157483374009 0.8200227248982055 1.0 1.0 6 P11047 1
Signaling by braf and raf1 fusions 0.2799505969534754 0.2206519014994636 0.825363485356384 1.0 1.0 19 P27361,Q9NRY5,Q96PU8,Q02750,P51114,O00203,P31946,Q7Z2W4,O43252,Q7KZF4,P18206,Q6WCQ1,P28482,Q9Y490,P41240,P46940,P30086,P02545 18
Suppression of phagosomal maturation 0.3806370417701715 0.2199132997007179 0.8259386781923228 1.0 1.0 5 P20339,Q14974 2
Cell cell junction organization 0.3453502662843072 0.2194715767299765 0.8262827186219537 1.0 1.0 7 Q9Y624,P55196,P19022,P35221,O60716,P35222 6
Vegfr2 mediated vascular permeability 0.3453502662843063 0.2194715767299736 0.8262827186219559 1.0 1.0 7 P07900,P42345,P35221,Q13177,O60716,P35222 6
Nuclear events kinase and transcription factor activation 0.297222794734614 0.2144160210217501 0.8302226492080687 1.0 1.0 13 Q15418,P51452,Q00535,P50570 4
Foxo mediated transcription 0.3266690527709532 0.2085533570728701 0.8347969254673244 1.0 1.0 8 Q13547,P63104,P04179 3
L1cam interactions 0.2631571184131783 0.2077432789805962 0.8354294230591996 1.0 1.0 34 P15311,Q96S59,Q16555,Q02750,P26038,P35241,P11047,O14786,Q9BUF5,P68371,P50570,Q15418,P53680,O95372 14
Recognition of dna damage by pcna containing replication complex 0.2941970375214656 0.2040443775162578 0.8383188200921103 1.0 1.0 13 P41440 1
Mrna decay by 5 to 3 exoribonuclease 0.3736623113708263 0.2024264758696416 0.8395833320620651 1.0 1.0 5 P62312 1
Activation of bad and translocation to mitochondria 0.3493038493038494 0.2013293122383055 0.8404410839381111 1.0 1.0 6 P61981,Q04917,P31946,P27348,P63104 5
Sulfur amino acid metabolism 0.3377009414612401 0.1984586593762505 0.8426862264456028 1.0 1.0 7 Q99707 1
Gap filling dna repair synthesis and ligation in gg ner 0.2923835503326942 0.1979395869958891 0.843092330949399 1.0 1.0 13 P41440 1
Translation of replicase and assembly of the replication transcription complex 0.5061287114653507 0.1933586269899202 0.8466781148247429 1.0 1.0 3 O43633 1
Sensory processing of sound by outer hair cells of the cochlea 0.3055826287621399 0.1898043663110525 0.8494624342735824 1.0 1.0 9 P35579,P15311,P26038,P35241,Q13813 5
Abortive elongation of hiv 1 transcript in the absence of tat 0.2976617354692255 0.1853990841695358 0.8529160266961096 1.0 1.0 10 Q8WX92,O00267,Q9H3P2 3
Formation of the early elongation complex 0.2904816611782929 0.1839958917146824 0.8540166778388407 1.0 1.0 11 Q8WX92,O00267,Q9H3P2 3
Regulation of tp53 activity through methylation 0.3652238419644201 0.1822719587572502 0.8553693037115093 1.0 1.0 5 O14744 1
Dual incision in gg ner 0.2834243591864455 0.1811107274461427 0.8562806645570955 1.0 1.0 15 P41440 1
Negative regulation of the pi3k akt network 0.3010876604018324 0.1772394652376295 0.8593202975779877 1.0 1.0 9 Q06124 1
Tp53 regulates transcription of cell cycle genes 0.2863366700170771 0.1741704831276988 0.8617314820149438 1.0 1.0 12 Q9C0C2,Q86X55,Q07812,Q99873,Q92600 5
Dag and ip3 signaling 0.3986191603116018 0.1663724634109921 0.8678638429414556 1.0 1.0 4 P10644 1
Met activates ras signaling 0.3978373726544437 0.1647919836086014 0.8691077139313876 1.0 1.0 4 P62993 1
Resolution of ap sites via the multiple nucleotide patch replacement pathway 0.2779742339791392 0.1629698396541598 0.8705421816331682 1.0 1.0 15 P27695,P41440,P39748,Q07864,P15927 5
Regulation of localization of foxo transcription factors 0.3956628477905048 0.1604414726540846 0.8725333222885292 1.0 1.0 4 P27348,P61981,P63104 3
G protein mediated events 0.3316953316953291 0.1582950533549446 0.8742243058524495 1.0 1.0 6 P08754,P17612,P10644,P28482,P52292 5
Inlb mediated entry of listeria monocytogenes into host cell 0.3935652318175399 0.1563084833227707 0.8757898698071633 1.0 1.0 4 P62993,P42566 2
Rhobtb gtpase cycle 0.2562336709659285 0.1537732309298246 0.8777885413827575 1.0 1.0 28 Q9NYL9,Q5VTR2,P38159,Q7Z6E9,P12814,O43396,Q8N684,P61201,P08670 9
Cell cycle mitotic 0.2503596911997849 0.1525409447200646 0.8787602990589223 1.0 1.0 201 P31350,P30260,Q99460,P28072,P28074,Q9UL46,P28070,O00231,O43237,P14635,Q99436,P41440,P49642,P39748,Q07864,P51665,Q86XL3,P33993,Q8N3U4,Q15691,Q8NFH4,Q9UJX2,P30153,O43633,P63151,O43264,O43683,O60763,Q01105,P27694,P33991,P49721,Q15021,Q9UNM6,Q14974,P06493,P17612,P35998,O75935,P68371,P62191,Q7Z460,P20618,Q8NI77,Q13409,O95684,O43242,Q13547,O14818,P06400,P25205,P15927,P49643,Q92973,Q16763,Q14203,P51530,P48556,Q9Y6G9,Q9UJX4,P25789,P25787,Q9BRT9,Q9Y2U8,Q9BUF5,Q9P258,P11802,Q92530,P00374,Q13200,O43768,P63208,Q9NTJ3,Q9Y266,P09884,Q9UN37,P60900,Q15008,Q06323 79
Rap1 signalling 0.4836082984238836 0.1523003166233955 0.8789500752042183 1.0 1.0 3 P17612 1
Aurka activation by tpx2 0.2586739275523161 0.1509786982534979 0.8799925195934146 1.0 1.0 23 Q15691,O95684,Q13409 3
Uptake and actions of bacterial toxins 0.3284193284193261 0.1508843733848727 0.8800669275854427 1.0 1.0 6 P07900,Q02750,Q8WUM4,P13639,P08238 5
Recycling pathway of l1 0.2579070650727979 0.1479374704705873 0.882392116387883 1.0 1.0 20 P15311,Q16555,P26038,P35241,Q9BUF5,P50570,Q15418,P53680 8
Copi mediated anterograde transport 0.242814813293636 0.1456026659405127 0.8842350633002005 1.0 1.0 45 P46459,Q14789,Q01082,Q14204,Q92538,Q14203,Q8N6T3,Q9Y6G9,O60763,Q13813,Q9UJW0,O43237,P35606,P18085,P61163,O75935,Q9BUF5,P68371,P53618,P83436,P61923,Q13409,Q9UBF2,Q9Y678,Q9BVK6,P53621 26
Apoptotic execution phase 0.255247102130586 0.1444195989021962 0.8851691413561655 1.0 1.0 26 O00273,Q9UDY2 2
Darpp 32 events 0.2996065990908427 0.1384494025802586 0.8898852553048955 1.0 1.0 8 P10644,P30153,Q00535,P17612 4
Listeria monocytogenes entry into host cells 0.3189663780229821 0.1305713214752646 0.8961144306085023 1.0 1.0 6 P62993,P42566 2
Interleukin 17 signaling 0.2672460698769888 0.1297989023928325 0.8967255313326294 1.0 1.0 15 P51452,P61088,P63208,Q02750,Q14738,Q15418,P30153 7
Runx2 regulates osteoblast differentiation 0.3772504091652985 0.1263106770604363 0.8994860048802396 1.0 1.0 4 P27361,Q13951,P06400 3
Copi independent golgi to er retrograde traffic 0.2520747159291795 0.1238417944102398 0.9014405393553426 1.0 1.0 22 Q14203,Q9Y6G9,Q13409,Q15042 4
Recruitment of numa to mitotic centrosomes 0.2482833718292483 0.1178872684678212 0.9061569811917876 1.0 1.0 27 P06493,Q13409,P17612,Q14203,O95684,Q15691,O75935,Q9BUF5,P68371,P30153 10
Scavenging by class f receptors 0.3702945990180029 0.1146825895733607 0.9086967143743698 1.0 1.0 4 Q92598,P07900,P27797 3
Ca dependent events 0.3315595579205906 0.1132245027391377 0.909852570199208 1.0 1.0 5 P10644,P28482,P17612,P52292 4
Rho gtpases activate nadph oxidases 0.3283620157434607 0.1076291871880071 0.9142898434437876 1.0 1.0 5 Q13526 1
Sars cov 1 infection 0.2613222404106093 0.1055414803464137 0.915946157208986 1.0 1.0 11 O43633,Q99570 2
Nuclear events stimulated by alk signaling in cancer 0.2607406480519789 0.1043864291053931 0.9168626918493948 1.0 1.0 12 P63208,Q86WB0,P40763 3
Tp53 regulates transcription of genes involved in g2 cell cycle arrest 0.2825131497200211 0.1019053249324819 0.9188318232846552 1.0 1.0 8 P14635,Q99873,Q07812,Q86X55 4
Interaction between l1 and ankyrins 0.4486707566462258 0.1003703433752065 0.9200503134045082 1.0 1.0 3 Q01082,Q13813 2
Adora2b mediated anti inflammatory cytokines production 0.3233729021694649 0.0992334004641509 0.920952955992127 1.0 1.0 5 P10644,P08754,P13861,P17612 4
Phosphorylation of emi1 0.4475122390854619 0.0988910393244934 0.9212247836146435 1.0 1.0 3 P14635 1
Resolution of abasic sites ap sites 0.2519243483240352 0.0968418867170302 0.9228519594524438 1.0 1.0 17 P27695,P41440,P39748,Q07864,P15927 5
Irf3 mediated induction of type i ifn 0.3176422431436771 0.090090733788921 0.9282151126420088 1.0 1.0 5 Q9UJV9,P78527,P12956,P13010 4
Telomere c strand lagging strand synthesis 0.2472354041484851 0.0897225409284894 0.9285077031120632 1.0 1.0 18 P41440,P49642,P51530,P39748,P09884,P15927 6
Hiv elongation arrest and recovery 0.2530684040569593 0.087322249219825 0.9304153692492554 1.0 1.0 13 Q8WX92,O00267,Q08945,Q9H3P2 4
Cytosolic iron sulfur cluster assembly 0.2919400304499198 0.0813577542468742 0.9351574449175828 1.0 1.0 6 Q9Y5Y2 1
Rna polymerase ii transcription 0.2465005492053108 0.081295250455781 0.9352071510771112 1.0 1.0 250 Q92530,Q9C0C2,Q16763,Q9UQ84,Q9UPN9,P51530,P48556,P04179,Q9UJX4,Q9H3P2,Q99873,Q13200,Q12824,Q92547,O00267,P43246,P25789,Q92600,Q06124,P31350,P30260,Q04917,P25787,P49721,Q9H814,Q86X55,Q99460,Q13526,Q8WX92,P28072,P28074,Q9UL46,P28070,Q6PD62,P54619,P30876,Q14353,O15047,O00231,Q99436,P61964,Q9H9B1,P63208,Q13247,P51665,P15927,Q08945,Q9NQ88,Q9NYV4,Q9NVI1,O95983,P20618,Q15008,P11413,Q13451,O43242,Q8WXI9,Q9BXW9,Q8N684,Q9UJX2,P17931,Q00535,Q9ULK4,O14744,P11802,P60900,Q07812,Q13263,Q92804,Q06323,Q96J02 71
Amino acids regulate mtorc1 0.2702001046254585 0.0793567557709025 0.9367488640135264 1.0 1.0 8 P21281,Q6IAA8 2
Telomere c strand synthesis initiation 0.3092085250879887 0.0776005791357822 0.9381457816884696 1.0 1.0 5 P49642,P09884,P49643 3
Rab regulation of trafficking 0.2387587818128839 0.0763508019260156 0.9391400096683926 1.0 1.0 22 Q8TC07,Q15042 2
Activation of nima kinases nek9 nek6 nek7 0.3428805237315883 0.0755418668139985 0.9397835877789478 1.0 1.0 4 P14635,P06493,Q8TD19 3
Rhov gtpase cycle 0.2470757419979587 0.0743216544723114 0.9407544469030328 1.0 1.0 12 Q01082,Q03001,Q13813,O43396,Q13177,P60953,Q93008,P46940 8
Pyroptosis 0.3055802878058625 0.0725763922646779 0.942143213410171 1.0 1.0 5 O43633,Q07812 2
Polb dependent long patch base excision repair 0.335140637010478 0.0663715026195197 0.9470820577765002 1.0 1.0 4 P27695 1
Copii mediated vesicle transport 0.2351196186265067 0.0631262928944639 0.9496659373464872 1.0 1.0 23 Q15436 1
Glucagon like peptide 1 glp1 regulates insulin secretion 0.3314238952536787 0.0622509904436571 0.9503629566931032 1.0 1.0 4 P10644,P46940,P17612 3
Signal transduction by l1 0.2695616550593979 0.0593869971766852 0.952643869530282 1.0 1.0 7 P27361,P67870,P19784,Q02750,O14786,P28482 6
Translesion synthesis by y family dna polymerases bypasses lesions on dna template 0.2361989740186156 0.0549395347758862 0.9561866352289076 1.0 1.0 16 Q14258,Q07864,P15927,P41440 4
Establishment of sister chromatid cohesion 0.2731367731367689 0.0547573239339003 0.956331799928908 1.0 1.0 6 Q9UQE7,Q9NTI5,Q8N3U4,Q29RF7,O60216 5
Cohesin loading onto chromatin 0.2731367731367689 0.0547573239339003 0.956331799928908 1.0 1.0 6 Q9UQE7,Q9NTI5,Q8N3U4,Q29RF7,O60216 5
Pka activation in glucagon signalling 0.4002877235354208 0.0510292888783102 0.959302181795184 1.0 1.0 3 P10644 1
Fcgr3a mediated il10 synthesis 0.4002877235354208 0.0510292888783102 0.959302181795184 1.0 1.0 3 P10644 1
Creb1 phosphorylation through the activation of adenylate cyclase 0.4002877235354208 0.0510292888783102 0.959302181795184 1.0 1.0 3 P10644 1
Vasopressin regulates renal water homeostasis via aquaporins 0.4002877235354208 0.0510292888783102 0.959302181795184 1.0 1.0 3 P10644 1
Pka mediated phosphorylation of creb 0.4002877235354208 0.0510292888783102 0.959302181795184 1.0 1.0 3 P10644 1
Glucagon signaling in metabolic regulation 0.4002877235354208 0.0510292888783102 0.959302181795184 1.0 1.0 3 P10644 1
Wnt ligand biogenesis and trafficking 0.3983640081799596 0.0495618111317083 0.9604715795129486 1.0 1.0 3 O75436,Q96QK1 2
Hiv transcription elongation 0.2329019035243606 0.0469726636897169 0.9625350146868809 1.0 1.0 15 Q8WX92,O00267,Q08945,Q9H3P2 4
Jnk c jun kinases phosphorylation and activation mediated by activated human tak1 0.4088307440719637 0.0463676224066513 0.9630172423213188 1.0 1.0 2 P61088 1
Activation of atr in response to replication stress 0.23219545907369 0.0460039010981785 0.9633071405766932 1.0 1.0 13 P27694,P33993,P33991,P15927 4
Wnt5a dependent internalization of fzd4 0.2463850970072825 0.0444780641070089 0.9645233369764497 1.0 1.0 8 P09497 1
Wnt5a dependent internalization of fzd2 fzd5 and ror2 0.2463850970072825 0.0444780641070089 0.9645233369764497 1.0 1.0 8 P09497 1
Keratinization 0.2816209578387241 0.0444728772190207 0.964527471423164 1.0 1.0 5 Q14574,P15924,P14923,P07384 4
Formation of the cornified envelope 0.2816209578387241 0.0444728772190207 0.964527471423164 1.0 1.0 5 Q14574,P15924,P14923,P07384 4
Opioid signalling 0.2264552731157403 0.0404135148446221 0.967763455764164 1.0 1.0 11 P10644,P30153,Q00535,P17612 4
Role of abl in robo slit signaling 0.3848876181856681 0.04023004190939 0.9679097270306988 1.0 1.0 3 Q01518 1
Signaling by fgfr in disease 0.2286875819120703 0.0402183421230361 0.9679190545606372 1.0 1.0 13 O95684,P40763 2
Retrograde neurotrophin signalling 0.241393442622958 0.038558528896996 0.9692423668318196 1.0 1.0 8 O94973,P63010,Q96CW1,P09496,P50570,Q00610,P53680 7
Syndecan interactions 0.3813459598126525 0.0380418127443041 0.9696543443913744 1.0 1.0 3 Q9Y296 1
Negative feedback regulation of mapk pathway 0.3770961145194259 0.0355539780121897 0.9716380053251356 1.0 1.0 3 P27361,Q02750 2
Smad2 smad3 smad4 heterotrimer regulates transcription 0.3770961145194235 0.0355539780121883 0.9716380053251368 1.0 1.0 3 P27361,Q13547 2
Rna polymerase i transcription termination 0.2271422714227193 0.0352370188325495 0.9718907437897256 1.0 1.0 9 O95602,O15446,Q9H9Y6,P17480,Q3B726,P18074,P19388,Q9GZS1 8
Trafficking of ampa receptors 0.2412945514133542 0.0268761101608109 0.9785585479631912 1.0 1.0 7 P46459,O94973,P63010,Q96CW1,Q9UM54,P53680 6
Vldlr internalisation and degradation 0.2412945514133535 0.0268761101608103 0.9785585479631916 1.0 1.0 7 O94973,P63010,Q96CW1,P09496,Q00610,P53680 6
Trafficking of glur2 containing ampa receptors 0.2411957411957374 0.0227738542641396 0.9818306638892088 1.0 1.0 6 P46459,O94973,P63010,Q96CW1,P53680 5
Nef mediated cd4 down regulation 0.241195741195737 0.0227738542641393 0.9818306638892088 1.0 1.0 6 O94973,P63010,Q9UI12,Q96CW1,P53680 5
Nef mediated cd8 down regulation 0.241195741195737 0.0227738542641393 0.9818306638892088 1.0 1.0 6 O94973,P63010,Q9UI12,Q96CW1,P53680 5
Dna damage bypass 0.2193762599684106 0.0227201665600079 0.9818734893984756 1.0 1.0 18 P41440 1
Neurexins and neuroligins 0.3432672051482518 0.0205376776670197 0.983614455976214 1.0 1.0 3 Q96HC4 1
Nuclear signaling by erbb4 0.3378331982876555 0.0188157892141056 0.9849880580814204 1.0 1.0 3 P16949 1
Signaling by moderate kinase activity braf mutants 0.2086326345375085 0.0175704524026608 0.9859815286042516 1.0 1.0 10 Q02750,P18206,P30086,Q9Y490 4
Robo receptors bind akap5 0.3311529026982905 0.0166227522045453 0.9867375734306228 1.0 1.0 2 P17612 1
Rab gefs exchange gtp for gdp on rabs 0.2128625019263519 0.0138592567181059 0.9889422670345956 1.0 1.0 16 P31150,P20339,Q15042,Q9Y296,Q14C86 5
E2f enabled inhibition of pre replication complex formation 0.2930045877727885 0.0098541945057953 0.9921376175911863 1.0 1.0 3 P14635 1
Perk regulates gene expression 0.2025757074568981 0.0095268673203595 0.9923987746351656 1.0 1.0 12 Q92945,P05198,Q9Y2L1 3
Chl1 interactions 0.2691206543967199 0.0077349827235274 0.993828438247595 1.0 1.0 3 P11142,O14786 2