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interpro_active_site/advanced/idx2term.json

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+{}

interpro_active_site/basic/idx2term.json

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+{"0": "Serine/threonine-protein kinase, active site [IPR008271]"}

interpro_active_site/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:41f41bb3415495fb7b748e37c6d0cd4125f779cfa41b360936f4b3fdd2a06115
+size 55272

interpro_active_site/df_merge.tsv

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+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_active_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2448,
+    "annotations_size": 49,
+    "title": "Average number of proteins per term",
+    "value": 2.3469387755102042
+}

interpro_active_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C333/C333_val_log2fc"}

interpro_active_site/result.tsv

@@ -0,0 +1,7 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Ubiquitin-conjugating enzyme, active site [IPR023313]	0.6598444535407291	1.3681275697723152	0.1712721483070118	0.999899495662978	0.5119692259821791	5	P68036,P61086,P61088,Q16763	4
+Serine carboxypeptidase, serine active site [IPR018202]	0.7946830265848561	1.3010644165531695	0.1932364063964411	0.9999730494086818	0.5119692259821791	3	Q9HB40,P10619	2
+Ubiquitin-activating enzyme E1, Cys active site [IPR033127]	0.6938238458391539	0.909986140873421	0.3628298188015901	0.9999999997438368	0.7198484267602281	3	Q8TBC4	1
+Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]	0.6807031888798094	0.4548907813239459	0.6491878153669268	1.0	0.9447252888879304	2	Q9NQ88	1
+Cysteine peptidase, cysteine active site [IPR000169]	0.4812918914695401	0.2261437455377652	0.8210896217279671	1.0	0.971574612875536	3	Q13867	1
+Serine/threonine-protein kinase, active site [IPR008271]	0.3448236080828172	0.1348922207439788	0.8926970902818645	1.0	0.971574612875536	32	Q00535,Q13464,P51812,Q15418,Q13177,O43683,P06493,P11802,Q96KB5	9

interpro_active_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenylosuccinate synthase,  active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, cysteine active site [IPR000169]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADSS", "APEH", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "AURKA", "BLMH", "BUB1", "CAPN1", "CAPN2", "CDK1", "CDK12", "CDK4", "CDK5", "CHEK2", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "FASN", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLUD1", "GSK3B", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "LDHA", "LDHB", "LONP1", "MAP2K1", "MAPK1", "MAPK3", "MDH1", "MDH2", "NEK9", "NME1", "NME2", "OXCT1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKN2", "PLK1", "PREP", "PRKACA", "PRPF4B", "PTK7", "PTPN1", "PTPN11", "RNASET2", "ROCK1", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TPI1", "TPP2", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UMPS", "VRK1", "VRK2"], "leading_proteins": ["BLMH", "BUB1", "CDK1", "CDK4", "CDK5", "CTSA", "PAK2", "PBK", "ROCK1", "RPS6KA1", "RPS6KA3", "SCPEP1", "TIGAR", "UBA3", "UBE2K", "UBE2L3", "UBE2N", "UBE2S"]}

interpro_binding_site/advanced/idx2term.json

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+{}

interpro_binding_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "EF-Hand 1, calcium-binding site [IPR018247]", "1": "Protein kinase, ATP binding site [IPR017441]"}

interpro_binding_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:8b66435eedc8951d09ac852ea4bf27c74d5a59e146bc9679428a24b71f1000a2
+size 56905

interpro_binding_site/df_merge.tsv

@@ -0,0 +1,2 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Beta tubulin, autoregulation binding site [IPR013838]	4	5	2.4701971153659006	0.013503861988078	3.5533980582524274	5.54126213592233	0.5823511994709325	0.3808337519133083	1.5578062452886454	0.9632803779920796	1.1906256051626651	0.3058955364405814	1.0	1.0	1.0	9.515842072742196e-07	2.8311070051942505e-05

interpro_binding_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2448,
+    "annotations_size": 30,
+    "title": "Average number of proteins per term",
+    "value": 3.8
+}

interpro_binding_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C333/C333_val_log2fc"}

interpro_binding_site/result.tsv

@@ -0,0 +1,6 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Beta tubulin, autoregulation binding site [IPR013838]	0.9185427752762998	2.4701971153659006	0.013503861988078	0.3349386925794331	0.202557929821171	5	Q13885,P68371,P07437,Q9BVA1	4
+Peptidase M16, zinc-binding site [IPR001431]	0.4971094649250155	0.6594453598042564	0.5096098224041681	0.9999999994797012	0.9417715072369064	5	O43847,Q10713	2
+EF-Hand 1, calcium-binding site [IPR018247]	0.3813068871494577	0.3050075224363854	0.7603604230671435	1.0	0.9417715072369064	31	Q02818,Q15293,O43852,P80303,Q14257,Q96AY3	6
+Protein kinase, ATP binding site [IPR017441]	0.3576224134805502	0.2574901751041704	0.7968003988154178	1.0	0.9417715072369064	27	Q00535,Q13464,P51812,P41240,Q15418,Q13177,O43683,P06493,P11802	9
+PPM-type phosphatase, divalent cation binding [IPR000222]	0.5241210139002555	0.107282167130494	0.9145651314547	1.0	0.9417715072369064	2	O15355	1

interpro_binding_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO2", "ACTN1", "ACTN4", "ADSS", "APEX1", "ARG2", "AURKA", "BPNT1", "BUB1", "CALM3", "CALU", "CAPN1", "CAPN2", "CDK1", "CDK12", "CDK4", "CDK5", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPS15", "FKBP10", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQGAP1", "IQGAP2", "LETM1", "MACF1", "MAP2K1", "MAPK1", "MAPK14", "MAPK3", "MCCC1", "METAP2", "MYH10", "MYH9", "MYO1B", "MYO1C", "MYO1D", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXCT1", "PA2G4", "PAK2", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKN2", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "PPM1G", "PRKACA", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "RPS6KA1", "RPS6KA3", "S100A11", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "TKT", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4B", "TUBB6", "UBE3C", "UQCRC2", "VRK1"], "leading_proteins": ["BUB1", "CALU", "CDK1", "CDK4", "CDK5", "CSK", "FKBP10", "NRDC", "NUCB1", "NUCB2", "PAK2", "PMPCA", "PPM1G", "RCN1", "RCN2", "ROCK1", "RPS6KA1", "RPS6KA3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4B"]}

interpro_conserved_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Proteasome beta-type subunit, conserved site [IPR016050]"}

interpro_conserved_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Proteasome beta-type subunit, conserved site [IPR016050]", "1": "Ubiquitin specific protease, conserved site [IPR018200]"}

interpro_conserved_site/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:7ad6867e7b3acc7c19f189c96b71e56956a4c24df14c97e23330aa53aa059017
+size 61822

interpro_conserved_site/df_merge.tsv

@@ -0,0 +1,3 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Proteasome beta-type subunit, conserved site [IPR016050]	5	8	3.058606144212637	0.0022236928776417	3.7135922330097086	7.970873786407767	1.4913184573846054	0.1902243906475925	1.515457478026574	0.1681602725795027	1.0170822776023185	0.2455850375425174	1.3803999540507549e-05	1.2225095413484733e-05	1.795667029584697e-08	3.77413242971045e-08	2.2585304294532336e-06
+Tubulin, conserved site [IPR017975]	4	5	2.4701971153659006	0.013503861988078	3.6140776699029127	5.883495145631068	0.537603280896448	0.3771225437200781	1.6631634011190108	1.117390952728082	1.2199662970774952	0.3090115161057067	1.0	1.0	1.0	5.4054011518008696e-05	0.0013369974246366

interpro_conserved_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2448,
+    "annotations_size": 259,
+    "title": "Average number of proteins per term",
+    "value": 2.444015444015444
+}

interpro_conserved_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C333/C333_val_log2fc"}

interpro_conserved_site/result.tsv

@@ -0,0 +1,33 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Proteasome beta-type subunit, conserved site [IPR016050]	0.933276890782792	3.0586061442126375	0.0022236928776417	0.4381822439061783	0.5759364553092243	8	P20618,Q99436,P28072,P49721,P28070	5
+Tubulin, conserved site [IPR017975]	0.9185427752762998	2.4701971153659006	0.013503861988078	0.9704399031544592	0.600271783261816	5	Q13885,P68371,P07437,Q9BVA1	4
+Thioredoxin, conserved site [IPR017937]	0.6522925660883161	1.83443931812409	0.0665888077027418	0.9999999822618608	0.6569921604217382	9	Q9H3N1,O43396,Q9H1E5	3
+Mini-chromosome maintenance, conserved site [IPR018525]	0.7085372093830655	1.6650210787776725	0.0959085505247263	0.9999999999954396	0.6569921604217382	6	Q14566,P49736,P25205,P33993	4
+14-3-3 protein, conserved site [IPR023409]	0.6728866765323538	1.5035070551513805	0.1327083389959744	1.0	0.6569921604217382	6	P62258,Q04917,P63104	3
+Haem oxygenase conserved site [IPR018207]	0.943172526573999	1.4181708792793168	0.1561408816437435	1.0	0.6569921604217382	2	P30519	1
+Aldehyde dehydrogenase, glutamic acid active site [IPR029510]	0.565944039469275	1.1471878130646296	0.2513040072526511	1.0	0.8035523194868721	7	P30837,P49419	2
+Zinc finger, RING-type, conserved site [IPR017907]	0.4731146008158799	1.033672364709233	0.3012893566207857	1.0	0.8686359680943828	11	P19474,Q14258,O75150	3
+HMG box A DNA-binding domain, conserved site [IPR017967]	0.8319705641864277	0.9849042307588426	0.3246711150361743	1.0	0.8686359680943828	2	O15347	1
+Intermediate filament protein, conserved site [IPR018039]	0.5676325136702001	0.9601079089941672	0.337000908371238	1.0	0.8686359680943828	5	P08670	1
+Clathrin adaptor complex, small chain [IPR000804]	0.7026123738972383	0.9434669683686006	0.3454421031417816	1.0	0.8686359680943828	3	P61923	1
+Ubiquitin specific protease, conserved site [IPR018200]	0.4691982686459571	0.8635304364367449	0.3878458925032533	1.0	0.8889565146755982	9	Q9Y4E8,Q96K76,P45974,Q8TEY7,Q86UV5	5
+FERM conserved site [IPR019747]	0.5053308643165171	0.7418449609887685	0.4581812760292512	1.0	0.952776203194287	6	P35241,P26038	2
+Dynamin, GTPase region, conserved site [IPR019762]	0.7632869991823414	0.7302466221899004	0.4652394491701859	1.0	0.952776203194287	2	P50570	1
+DnaJ domain, conserved site [IPR018253]	0.4551026072337794	0.6196146478367434	0.5355115207440946	1.0	0.9549121091322356	7	P31689,P25685,Q8WXX5,Q96KC8	4
+Profilin conserved site [IPR027310]	0.7068683565004136	0.5371832866767474	0.5911410148276393	1.0	0.9549121091322356	2	P07737	1
+Phosphorylase pyridoxal-phosphate attachment site [IPR035090]	0.6508585445625574	0.3681102632739534	0.7127910184091484	1.0	0.9692579902039522	2	P06737	1
+Amyloidogenic glycoprotein,  copper-binding domain conserved site [IPR019744]	0.631234668847104	0.3157344481309975	0.7522040773397467	1.0	0.9692579902039522	2	Q06481	1
+Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]	0.631234668847104	0.3157344481309975	0.7522040773397467	1.0	0.9692579902039522	2	Q06481	1
+Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]	0.631234668847104	0.3157344481309975	0.7522040773397467	1.0	0.9692579902039522	2	Q06481	1
+Clathrin adaptor, mu subunit, conserved site [IPR018240]	0.4951392082229435	0.2586362794860339	0.7959158884270765	1.0	0.9749389388082208	3	Q9Y2T2	1
+AT hook, DNA-binding motif [IPR017956]	0.5968928863450611	0.2340937484259164	0.8149121991464452	1.0	0.9749389388082208	2	Q6ZRS2	1
+GTP1/OBG, conserved site [IPR006074]	0.5891251022076942	0.2175082887958992	0.8278122480951182	1.0	0.9749389388082208	2	P55039	1
+Ubiquitin-activating enzyme E1, conserved site [IPR018074]	0.5829926410466151	0.2049221192618589	0.8376329732585373	1.0	0.9749389388082208	2	Q9UBT2	1
+Chromo domain, conserved site [IPR023779]	0.3479328694228421	0.1600018515079411	0.8728796157165519	1.0	0.9749389388082208	5	Q13185,O14646,Q99549,P83916	4
+Ras GTPase-activating protein, conserved site [IPR023152]	0.5421095666394209	0.1326675298709501	0.8944563232311904	1.0	0.9749389388082208	2	Q13576	1
+Aldo/keto reductase, conserved site [IPR018170]	0.5302534750613346	0.1155042568002021	0.9080454466223152	1.0	0.9749389388082208	2	P14550	1
+Alpha-D-phosphohexomutase, conserved site [IPR016066]	0.4159509202454046	0.1058884508072932	0.9156708574698468	1.0	0.9749389388082208	3	Q96G03,O95394	2
+Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]	0.5163532297628887	0.0974974843329524	0.9223313319257492	1.0	0.9750359794643636	2	P04439	1
+Aldehyde dehydrogenase, cysteine active site [IPR016160]	0.2930338712231021	0.0562967478407349	0.9551054095751794	1.0	0.997468955967627	7	P30837	1
+Vinculin, conserved site [IPR000633]	0.454210956663953	0.042346068097496	0.9662228211695004	1.0	0.9979663046261448	2	P18206	1
+Phosphofructokinase, conserved site [IPR015912]	0.3165644171779113	0.0218674400907458	0.9825536976048916	1.0	0.9979663046261448	3	P08237,P17858	2

interpro_conserved_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Amyloidogenic glycoprotein,  copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific,  conserved site [IPR031303]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P,  conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor, T-box, conserved site [IPR018186]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR1A", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AK1", "AK2", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "APEX1", "APLP2", "APP", "ATAD1", "ATP5C1", "ATP5O", "BAG6", "BAX", "BAZ1A", "BAZ1B", "BCAT2", "BDH2", "BLM", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD2", "BRD4", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CBR1", "CBX1", "CBX3", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDH2", "CDKAL1", "CHAF1B", "CHD1", "CHD4", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1C", "CPOX", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX40", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJC1", "DNAJC11", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DRG1", "DRG2", "DSC3", "DSG2", "DST", "DTYMK", "DYNLL1", "EARS2", "ECH1", "ECHS1", "ECI1", "ECI2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "ENO1", "EPB41", "EPB41L2", "EPDR1", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXC1", "FUCA1", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLO1", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GRWD1", "GSPT1", "GTF3C2", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB3", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IDH1", "IDH2", "IDH3A", "IDH3B", "ILVBL", "IMPDH2", "IQGAP1", "IQGAP2", "IVD", "KDM2A", "KDSR", "KIF11", "KIF18A", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MAPK3", "MARS", "MAT2A", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME2", "MGA", "MGST2", "MIF", "MPHOSPH8", "MPI", "MPP6", "MPST", "MRPL24", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFV1", "NEFM", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD2", "NSF", "NUBP2", "NUBPL", "NUDT1", "NUDT5", "NUP153", "NUP37", "NVL", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF14", "PHF3", "PHF8", "PHGDH", "PHIP", "PI4KB", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PNP", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "RACK1", "RAE1", "RANBP2", "RARS", "RBBP7", "RCL1", "RDH13", "RDX", "RIDA", "RNF114", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "S100A10", "S100A11", "SART1", "SBDS", "SCAF11", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC27A4", "SLIT2", "SMARCA4", "SMU1", "SNRNP40", "SPATA5", "SPATA5L1", "SPTBN1", "SRCAP", "SRM", "STMN1", "STX12", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "TBL3", "TCP1", "TK1", "TLN1", "TMX1", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM21", "TRIM25", "TRIM27", "TRIM28", "TRIM33", "TRIP13", "TSFM", "TSPAN3", "TSPAN6", "TUBB", "TUBB2A", "TUBB2B", "TUBB4B", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UHRF1", "USP10", "USP14", "USP15", "USP33", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZMYND8"], "leading_proteins": ["AKR1A1", "ALDH1B1", "ALDH7A1", "AP3M1", "APLP2", "CBX1", "CBX3", "CHD1", "COPZ1", "DNAJA1", "DNAJB1", "DNAJC1", "DNAJC9", "DNM2", "DRG2", "HLA-A", "HMGB3", "HMOX2", "IQGAP2", "MCM2", "MCM3", "MCM6", "MCM7", "MPHOSPH8", "MSN", "PFKL", "PFKM", "PFN1", "PGM2", "PGM3", "PSMB1", "PSMB2", "PSMB4", "PSMB6", "PSMB7", "PYGL", "RDX", "RNF40", "SRCAP", "TMX1", "TMX4", "TRIM21", "TRIM25", "TUBB", "TUBB2A", "TUBB2B", "TUBB4B", "TXNL1", "UBA2", "USP15", "USP33", "USP47", "USP48", "USP5", "VCL", "VIM", "YWHAE", "YWHAH", "YWHAZ"]}

interpro_domain/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Proteasome component (PCI) domain [IPR000717]", "1": "Ubiquitin-associated domain [IPR015940]", "2": "Importin-beta, N-terminal domain [IPR001494]"}

interpro_domain/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Proteasome component (PCI) domain [IPR000717]", "1": "Ubiquitin-associated domain [IPR015940]", "2": "Importin-beta, N-terminal domain [IPR001494]", "3": "K Homology domain, type 1 [IPR004088]", "4": "Proteasome alpha-subunit, N-terminal domain [IPR000426]", "5": "Thioredoxin domain [IPR013766]", "6": "K Homology domain [IPR004087]", "7": "RNA recognition motif domain, eukaryote [IPR003954]", "8": "Ubiquitin-conjugating enzyme E2 [IPR000608]", "9": "DnaJ domain [IPR001623]", "10": "Phox homology [IPR001683]", "11": "Chromo domain [IPR023780]", "12": "EF-hand domain [IPR002048]", "13": "TGS [IPR004095]", "14": "Actin-depolymerising factor homology domain [IPR002108]"}