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interpro_active_site/advanced/idx2term.json

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+{}

interpro_active_site/basic/idx2term.json

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+{}

interpro_active_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:2b262fdd45be0dffc55070cd499698f148ff6128836abfa0b2612a586006133a
+size 64109

interpro_active_site/df_merge.tsv

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+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_active_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2451,
+    "annotations_size": 50,
+    "title": "Average number of proteins per term",
+    "value": 2.3
+}

interpro_active_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C335/C335_val_log2fc"}

interpro_active_site/result.tsv

@@ -0,0 +1,4 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Thiolase, acyl-enzyme intermediate active site [IPR020615]	0.5933596177655796	1.3440449990437124	0.1789338360203596	0.9999476510754248	0.2386705508585737	4	P22307	1
+Cysteine peptidase, cysteine active site [IPR000169]	0.4424019607843155	0.658252370851697	0.5103759776821448	0.9999999999999996	0.5547564974805922	3	P17655,Q13867	2
+Tyrosine-protein kinase, active site [IPR008266]	0.3101505490205389	0.1779642942103325	0.8587510171594854	1.0	0.8587510171594854	3	P41240	1

interpro_active_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenylosuccinate synthase,  active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Cysteine peptidase, cysteine active site [IPR000169]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADSS", "AKT2", "APEH", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "BLMH", "CAMK2D", "CAMK2G", "CAPN1", "CAPN2", "CDC34", "CDK1", "CDK12", "CDK2", "CDK4", "CDK5", "CDK6", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CTSA", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLUD1", "GSK3A", "GSK3B", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "LDHA", "LDHB", "LONP1", "MAP2K1", "MARK2", "MDH1", "MDH2", "MTMR6", "NEK9", "NME1", "PAK2", "PBK", "PGAM1", "PKM", "PKN2", "PLK1", "PREP", "PRKACA", "PRPF4B", "PTK7", "PTPN1", "RIPK1", "RNASET2", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TPI1", "TPP2", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UMPS", "UNG", "VRK1"], "leading_proteins": ["BLMH", "CAPN2", "CSK", "SCP2"]}

interpro_binding_site/advanced/idx2term.json

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+{}

interpro_binding_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "EF-Hand 1, calcium-binding site [IPR018247]"}

interpro_binding_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:92a96fed17b7f6bb6b31d18d002e5e6b4acd1d4668947b58c644a6900eca1200
+size 59127

interpro_binding_site/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_binding_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2451,
+    "annotations_size": 27,
+    "title": "Average number of proteins per term",
+    "value": 4.111111111111111
+}

interpro_binding_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C335/C335_val_log2fc"}

interpro_binding_site/result.tsv

@@ -0,0 +1,5 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]	0.8758677011024885	2.629249954635884	0.0085573437148007	0.2070876049418916	0.0541138287856331	2	P34897	1
+Peptidase M16, zinc-binding site [IPR001431]	0.5612393834767883	1.1790282250342845	0.2383869369352278	0.9993590437621156	0.330445362242343	5	P22695,Q10713	2
+Aconitase family, 4Fe-4S cluster binding site [IPR018136]	0.5365455287872543	1.104787272710399	0.2692517766419091	0.999790236587356	0.330445362242343	2	P21399	1
+EF-Hand 1, calcium-binding site [IPR018247]	0.4817901763154067	0.710173756910164	0.4775963925925612	0.9999999756686326	0.5158041039999661	32	Q9Y680,Q02818,P30626,Q03001,O75746,P80303,O95202,Q6NUK1,O75340,Q96AY3,Q8IXI2,Q9NWM8,P43304	13

interpro_binding_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Protein kinase, ATP binding site [IPR017441]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "ARG2", "CALU", "CAMK2D", "CAMK2G", "CAPN1", "CAPN2", "CDK1", "CDK12", "CDK2", "CDK4", "CDK5", "CDK6", "COX2", "COX5B", "CSK", "CSNK1A1", "CYB5B", "DLAT", "DLST", "DST", "EHD1", "EIF2AK2", "EPHA7", "FKBP10", "FKBP14", "FKBP7", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "GSK3B", "HK1", "HK2", "IDE", "ILKAP", "IQGAP1", "LETM1", "MACF1", "MAP2K1", "MARK2", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1C", "NRDC", "NUCB1", "NUCB2", "PA2G4", "PAK2", "PAK4", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKN2", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "PPM1G", "PRKACA", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SRI", "SRPK1", "SRPK2", "TKT", "TTK", "TUBB", "TUBB2B", "TUBB4B", "TUBB6", "UBE3C", "UQCRC2", "VRK1"], "leading_proteins": ["ACO1", "DST", "FKBP10", "FKBP14", "FKBP7", "GPD2", "LETM1", "NUCB1", "NUCB2", "PDCD6", "PMPCA", "RHOT1", "SHMT2", "SLC25A12", "SLC25A24", "SRI", "UQCRC2"]}

interpro_conserved_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Proteasome beta-type subunit, conserved site [IPR016050]"}

interpro_conserved_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Proteasome beta-type subunit, conserved site [IPR016050]", "1": "Heat shock protein 70, conserved site [IPR018181]"}

interpro_conserved_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:ba3e62a23cc83ba03055b01c6e9bb379d1abf97f8ce7c926c92557126a5e12c4
+size 99348

interpro_conserved_site/df_merge.tsv

@@ -0,0 +1,3 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Thiolase, conserved site [IPR020613]	0	5	2.2850289731107902	0.0223111289446571	2.844660194174758	5.844660194174757	-0.5424048525012372	0.3903098970250164	1.8394663723529816	0.3622283127413132	1.063196584101526	0.2860337389117996	1.0	0.028497516818446	0.0568757538574934	0.1373795195898598	0.0312108672695238
+Proteasome beta-type subunit, conserved site [IPR016050]	7	8	2.007540801454321	0.0446921107075475	3.7135922330097086	7.970873786407767	1.4913184573846054	0.1902243906475925	1.515457478026574	0.1681602725795027	1.0170822776023185	0.2455850375425174	1.0	0.0470522829573702	0.0001014210629885	0.0015031185668187	5.542830198350017e-05

interpro_conserved_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2451,
+    "annotations_size": 252,
+    "title": "Average number of proteins per term",
+    "value": 2.488095238095238
+}

interpro_conserved_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C335/C335_val_log2fc"}

interpro_conserved_site/result.tsv

@@ -0,0 +1,30 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]	0.9697588884348188	2.995572888864225	0.0027392982457343	0.4990506902785425	0.0404494399671637	4	Q8WWV3,Q99536,Q8N4Q0	3
+Purine phosphorylase, family 2, conserved site [IPR018099]	0.8040016333197215	2.325017220443426	0.0200710394136238	0.993959993458016	0.0748967863503168	2	Q13126	1
+Aldo/keto reductase, conserved site [IPR018170]	0.789301755818695	2.261397666237339	0.0237346431544087	0.997649797001228	0.0768219730687232	2	P14550	1
+Adenylate kinase, conserved site [IPR033690]	0.7638888888888897	2.138994282308567	0.03243613144092	0.999753810315783	0.0939529324495615	3	P00568,P54819	2
+Haem oxygenase conserved site [IPR018207]	0.7472437729685515	2.07677479012069	0.037822350025074	0.999939698698095	0.0993009788422223	2	P30519	1
+3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]	0.7439771335238856	2.062275560467464	0.0391815084441766	0.9999577700184306	0.1007524502850257	2	Q16836	1
+Proteasome beta-type subunit, conserved site [IPR016050]	0.7429390094146547	2.007540801454321	0.0446921107075475	0.999990088764154	0.1104158029245291	8	P25789,P20618,P28070,P28074,Q99436,P49721,P28072	7
+Actin, conserved site [IPR004001]	0.6523602714666377	1.633582978106879	0.1023464443830444	0.9999999999984746	0.1816289012994872	3	P61163	1
+Aldehyde dehydrogenase, glutamic acid active site [IPR029510]	0.6499505422751675	1.5800248805999006	0.1141011686912596	0.9999999999999448	0.1891677270407725	7	O94788,P49419	2
+Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]	0.6218864842792937	1.505387550635581	0.1322244678875042	0.9999999999999996	0.2061890217775088	2	P24534	1
+ABC transporter-like, conserved site [IPR017871]	0.6089037521182123	1.3727428234531878	0.1698323112564712	1.0	0.2488240839338997	9	P08183,P28288,O15439	3
+Dynamin, GTPase region, conserved site [IPR019762]	0.5863617803184937	1.3390495075228492	0.1805545564699631	1.0	0.2556165630923073	2	P50570	1
+Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]	0.554905016603635	1.0889806059666296	0.2761624381890792	1.0	0.3399804951733068	13	Q9NSE4,Q5T160,Q5ST30,Q9Y2Z4	4
+Calreticulin/calnexin, conserved site [IPR018124]	0.5173522223866787	0.999957823478724	0.3173309192601676	1.0	0.3736794002502909	3	O14967	1
+Aldehyde dehydrogenase, cysteine active site [IPR016160]	0.5213806736990589	0.9685390026593308	0.3327752500068865	1.0	0.3829194657613489	7	O94788	1
+Cullin, conserved site [IPR016157]	0.5119796525921572	0.9333935648176866	0.3506168017572411	1.0	0.3997983440851799	6	Q13619	1
+GTP1/OBG, conserved site [IPR006074]	0.4728460596161671	0.8092485417702694	0.4183721986165338	1.0	0.4706687234436006	2	P55039	1
+Guanylate kinase, conserved site [IPR020590]	0.4503879134340525	0.7082648775260184	0.4787807838217555	1.0	0.533861758951692	2	Q14168	1
+Thioredoxin, conserved site [IPR017937]	0.4698856788344318	0.7030890400959945	0.4820002618718657	1.0	0.5350839911529082	10	P07237,Q8IXB1	2
+AT hook, DNA-binding motif [IPR017956]	0.4493464052287599	0.6888157877533896	0.4909391991479956	1.0	0.5426170095846268	3	Q6ZRS2,P17096	2
+Chromo domain, conserved site [IPR023779]	0.4354575163398712	0.6280145119693032	0.5299944333917368	1.0	0.5832253153481121	3	P45973,P83916	2
+Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]	0.4152715394038418	0.5566193712036439	0.5777875158137491	1.0	0.6222327093378984	2	Q6UB35	1
+Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]	0.4152715394038369	0.5566193712036238	0.5777875158137629	1.0	0.6222327093378984	2	P13995	1
+14-3-3 protein, conserved site [IPR023409]	0.4201176599857195	0.5220706863461481	0.6016211154777547	1.0	0.6451426429804007	6	P62258,P61981,P27348	3
+S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]	0.3911800734993892	0.4587893859096472	0.6463854175726915	1.0	0.6902081577471113	2	O43865	1
+Heat shock protein Hsp90, conserved site [IPR019805]	0.3909313725490215	0.4440101834650824	0.6570352213810644	1.0	0.6932912644870491	3	P14625,P07900	2
+Intermediate filament protein, conserved site [IPR018039]	0.4008299572499622	0.4245479074629365	0.6711662745008355	1.0	0.6989004180752502	8	Q16352,P07197	2
+Clathrin adaptor, mu subunit, conserved site [IPR018240]	0.3733660130718974	0.3774433696113158	0.7058441418331143	1.0	0.7260111173140604	3	Q9BXS5,Q96CW1	2
+Heat shock protein 70, conserved site [IPR018181]	0.3042588042588001	0.1122869130373829	0.910595918061665	1.0	0.910595918061665	9	P34932,Q9Y4L1,P0DMV9,O95757,Q0VDF9,P38646,P11142,P48723	8

interpro_conserved_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Amyloidogenic glycoprotein,  copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Bromodomain, conserved site [IPR018359]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific,  conserved site [IPR031303]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Homeobox, conserved site [IPR017970]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RIO kinase, conserved site [IPR018935]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P,  conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]"], "available_proteins": ["AAAS", "ABCB1", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ACAA2", "ACAD9", "ACADM", "ACADS", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR1B", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP3M1", "AP3S1", "APEX1", "APLP2", "APP", "ARIH2", "ATAD1", "ATP5C1", "ATP5O", "BAG6", "BAZ1A", "BAZ1B", "BAZ2A", "BCAT2", "BLM", "BOP1", "BPTF", "BRCA1", "BRD2", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CBR1", "CBX1", "CBX3", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDKAL1", "CECR2", "CHAF1B", "CHD4", "CLGN", "CMPK1", "CNDP2", "COPA", "COPZ1", "CORO1B", "CORO1C", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX6", "DHCR7", "DHFR", "DHRS7", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX40", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DRG1", "DRG2", "DSG2", "DST", "DTYMK", "DYNLL1", "ECH1", "ECHS1", "ECI2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "ENO1", "EPB41", "EPB41L2", "EPHA7", "EPRS", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXC1", "FOXK1", "FUCA2", "GAA", "GALK1", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLO1", "GMPPA", "GNPDA1", "GNS", "GPI", "GRHPR", "GRWD1", "GSPT1", "GTF3C2", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HOXA10", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "ILVBL", "IMPDH2", "INA", "IQGAP1", "IVD", "KDM2A", "KDSR", "KIF11", "KIF14", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LARS", "LARS2", "LBR", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGST2", "MID1", "MIF", "MPI", "MPP2", "MPP6", "MPST", "MRPL24", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFV1", "NEFL", "NEFM", "NES", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD2", "NSF", "NUBP2", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL6", "OSBPL9", "P4HB", "PAFAH1B1", "PAICS", "PBRM1", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHGDH", "PHIP", "PI4KB", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PNP", "PNPLA6", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2E", "PPIB", "PPIC", "PPID", "PPIF", "PPIG", "PPIH", "PPIL1", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RCL1", "RDH13", "RDX", "RECQL5", "RIOK2", "RNF114", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RTN4IP1", "S100A10", "S100A11", "SART1", "SBDS", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC27A4", "SLIT2", "SMARCA4", "SMU1", "SNRNP40", "SNU13", "SPATA5", "SPTBN1", "SRCAP", "SRM", "STMN1", "STRN4", "STX12", "STX18", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SYNE2", "TAP1", "TAP2", "TBL3", "TCP1", "THOC6", "TK1", "TLN1", "TMX1", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TSFM", "TSPAN6", "TUBB", "TUBB2B", "TUBB4B", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UHRF1", "USP10", "USP14", "USP36", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4B", "WARS", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR36", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2"], "leading_proteins": ["ABCB1", "ABCC4", "ABCD3", "ACTR1A", "AHCYL1", "AK1", "AK2", "AKR1A1", "ALDH1A2", "ALDH7A1", "AP1M1", "AP2M1", "CBX1", "CBX5", "CLGN", "CUL4A", "DNAJC10", "DNM2", "DRG2", "EEF1B2", "HADH", "HMGA1", "HMOX2", "HSP90AA1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HYOU1", "IARS2", "INA", "MPP2", "MTAP", "MTHFD1L", "MTHFD2", "NEFM", "P4HB", "PSMA4", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "RARS2", "RTN4IP1", "SRCAP", "VARS2", "VAT1", "YARS2", "YWHAE", "YWHAG", "YWHAQ", "ZADH2"]}

interpro_domain/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]"}

interpro_domain/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]", "1": "RNA recognition motif domain [IPR000504]", "2": "Immunoglobulin-like domain [IPR007110]", "3": "Importin-beta, N-terminal domain [IPR001494]", "4": "EF-hand domain [IPR002048]", "5": "CS domain [IPR007052]", "6": "RNA-binding domain, S1 [IPR022967]", "7": "AAA+ ATPase domain [IPR003593]"}

interpro_domain/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:82d77c80c2353852b0e66c9750d9988f929c4edeaa2bb548ef140e455644f3f0
+size 461497

interpro_domain/df_merge.tsv

@@ -0,0 +1,10 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Alcohol dehydrogenase, N-terminal [IPR013154]	3	5	2.979203888050901	0.0028899840730185	1.3762135922330097	5.245145631067961	0.6000738304798152	0.3870290227769069	1.1994000251783288	0.9246362329357484	1.1062357688130569	0.3020782188917261	1.0	8.586603742440297e-06	1.0152328729907457e-06	3.9104524570814734e-05	0.0005776438679051
+Polyketide synthase, enoylreductase domain [IPR020843]	4	6	2.9240297862644185	0.0034553168111581	1.6189320388349515	6.283980582524272	0.4837477775906041	0.3583565743712875	1.2357658783365448	1.1656223303878015	1.2317099658487027	0.2921137785685181	0.0086012577525931	1.5156129912659306e-07	3.439117354577337e-08	3.3521637524966083e-06	9.75534858956266e-05
+Alcohol dehydrogenase-like, C-terminal [IPR013149]	3	6	2.8981259063337097	0.0037539985335257	1.7985436893203883	6.618932038834951	-0.2560580222022892	0.3144815454028563	1.2849758471282229	0.9126568625608084	1.3559762153751562	0.266510476207785	0.0070422251256385	8.586603742440297e-06	1.0152328729907457e-06	3.9104524570814734e-05	0.0005776438679051
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	3	7	2.2930347256820607	0.0218460057993148	2.813106796116505	6.104368932038835	1.6405397264547834	0.1100883340733615	1.2852875686886795	0.8042848477475721	1.100790504333474	0.1612592696854457	1.0	0.0014481500629001	0.0001833288791406	0.0001450038876457	0.0020183200628615
+Thiolase, N-terminal [IPR020616]	0	5	2.2850289731107902	0.0223111289446571	2.844660194174758	5.844660194174757	-0.5424048525012372	0.3903098970250164	1.8394663723529816	0.3622283127413132	1.063196584101526	0.2860337389117996	1.0	0.028497516818446	0.0568757538574934	0.1373795195898598	0.0312108672695238
+Thiolase, C-terminal [IPR020617]	0	5	2.2850289731107902	0.0223111289446571	2.844660194174758	5.844660194174757	-0.5424048525012372	0.3903098970250164	1.8394663723529816	0.3622283127413132	1.063196584101526	0.2860337389117996	1.0	0.028497516818446	0.0568757538574934	0.1373795195898598	0.0312108672695238
+FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]	5	9	2.2529083630805284	0.0242649274530042	3.1262135922330097	10.111650485436892	0.9686720267359892	0.3700536707457866	1.7316562118191232	1.203619216216406	0.9607394322697528	0.3108814801432357	1.0	0.0607401038440192	0.1191939669275513	0.0002054625318554	1.665940864684324e-05
+Glutathione S-transferase, N-terminal [IPR004045]	2	6	2.2048260109027784	0.0274663060629547	2.4635922330097086	7.354368932038835	0.1379245375050955	0.5007649291980636	1.692684060559357	0.9479949918991396	0.9964823876403148	0.2990443112345751	0.0086012577525931	0.0516364610584135	0.1018169846714528	0.0280420066437826	0.0141665154869097
+ABC transporter type 1, transmembrane domain [IPR011527]	3	6	1.975283167126748	0.0482360223909252	2.3689320388349513	6.349514563106796	0.6640264147492347	0.3307390797434538	1.7803691733569	2.1393617497725477	1.1694677427725269	0.279101120079799	1.0	0.0697581245313758	0.1362380906066266	0.005208827916976	0.0049531384619904

interpro_domain/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2451,
+    "annotations_size": 2196,
+    "title": "Average number of proteins per term",
+    "value": 2.0514571948998177
+}

interpro_domain/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C335/C335_val_log2fc"}

interpro_domain/result.tsv

@@ -0,0 +1,154 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Oxidoreductase, N-terminal domain [IPR041694]	0.9857084524295624	3.0730554255105127	0.002118791309146	0.9905127066174187	0.0413266427960271	2	Q14914	1
+Major facilitator superfamily domain [IPR020846]	0.9632503062474468	2.984323813212469	0.002842058246415	0.9980696339269916	0.0413266427960271	2	Q6NT16	1
+Alcohol dehydrogenase, N-terminal [IPR013154]	0.967139377571938	2.979203888050901	0.0028899840730185	0.9982629955604644	0.0413266427960271	5	Q99536,Q8WWV3,Q8N4Q0	3
+Polyketide synthase, enoylreductase domain [IPR020843]	0.9548371590744976	2.9240297862644185	0.0034553168111581	0.999500056392448	0.0413266427960271	6	Q8WWV3,Q99536,Q14914,Q8N4Q0	4
+Alcohol dehydrogenase-like, C-terminal [IPR013149]	0.948472560359473	2.8981259063337097	0.0037539985335257	0.9997411581200016	0.0413266427960271	6	Q14914,Q8N8N7,Q8N4Q0	3
+Saccharopine dehydrogenase-like, C-terminal [IPR032095]	0.9363005308289076	2.8765048258611343	0.0040210604678958	0.9998563383973512	0.0413266427960271	2	Q8NBX0	1
+Saccharopine dehydrogenase, NADP binding domain [IPR005097]	0.9363005308289076	2.8765048258611343	0.0040210604678958	0.9998563383973512	0.0413266427960271	2	Q8NBX0	1
+CARG-binding factor, N-terminal [IPR012956]	0.9085340955492032	2.7638552016116065	0.0057122881938189	0.9999965603811782	0.0430455303262263	2	Q99729	1
+Tim44-like domain [IPR007379]	0.8766843609636578	2.6326428054135693	0.008472339754701	0.9999999923190388	0.044970907616842	2	Q9BRJ2	1
+Serine hydroxymethyltransferase-like domain [IPR039429]	0.8758677011024885	2.629249954635884	0.0085573437148007	0.9999999936371724	0.0450645726563609	2	P34897	1
+Peptidase M3A/M3B catalytic domain [IPR001567]	0.8533496732026148	2.525473350245952	0.0115542544421769	0.9999999999917504	0.0504435571012586	3	Q9BYT8,Q99797	2
+Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]	0.8374846876276022	2.468161808036976	0.0135808914543957	0.999999999999909	0.054522189458598	2	O60506	1
+Zinc finger, CHHC-type [IPR012996]	0.8329248366013076	2.4387775256278377	0.0147370378860605	0.9999999999999932	0.0573510732781501	3	P52597,P31943	2
+Heat shock chaperonin-binding [IPR006636]	0.8328180640641085	2.4383219244448084	0.0147556267769375	0.9999999999999932	0.0573510732781501	3	Q9NRR5	1
+BAT2, N-terminal [IPR009738]	0.8229779800933343	2.396226993514891	0.0165648282940518	1.0	0.0601814424097881	3	Q5JSZ5	1
+Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547]	0.8158432013066506	2.375922041413	0.0175051608071776	1.0	0.0621684282658692	2	O15460	1
+Pentacotripeptide-repeat region of PRORP [IPR033443]	0.8052266231114724	2.330297485342139	0.0197904335822634	1.0	0.0670675804732259	2	O75127	1
+Nucleoside phosphorylase domain [IPR000845]	0.8040016333197215	2.325017220443426	0.0200710394136238	1.0	0.0677565230108199	2	Q13126	1
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	0.8059689933200818	2.2930347256820607	0.0218460057993148	1.0	0.0696278720984757	7	Q8WUJ1,Q9UMX5,O15173	3
+CTP synthase, N-terminal [IPR017456]	0.7954267047774559	2.2879633135984188	0.0221396576527665	1.0	0.069954947058238	2	P17812	1
+CTP synthase GATase domain [IPR033828]	0.7954267047774559	2.2879633135984188	0.0221396576527665	1.0	0.069954947058238	2	P17812	1
+FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]	0.7976617814602628	2.2529083630805284	0.0242649274530042	1.0	0.0731947536906556	9	Q9Y680,P26885,Q00688,O00170,Q9NWM8	5
+Vicinal oxygen chelate (VOC) domain [IPR037523]	0.7864434463046069	2.248972280945934	0.0245142596748364	1.0	0.0736433847413691	2	Q04760	1
+Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]	0.7859163509121098	2.2357777046539495	0.0253663360805984	1.0	0.0744712219692436	3	O15460	1
+6-phosphogluconate dehydrogenase, NADP-binding [IPR006115]	0.7794688002744572	2.2075578742071493	0.0272751084357221	1.0	0.0759572681568395	3	P31937	1
+Glutathione S-transferase, N-terminal [IPR004045]	0.7853731067900512	2.2048260109027784	0.0274663060629547	1.0	0.0759572681568395	6	P78417,O43708	2
+FAD dependent oxidoreductase [IPR006076]	0.7724104136770884	2.176560766236082	0.0295133551593242	1.0	0.0793284307587223	3	P43304	1
+FAD/NAD(P)-binding domain [IPR023753]	0.766549996612121	2.139981797373526	0.0323562378202053	1.0	0.0833970636774307	4	O95831	1
+Immunoglobulin V-set domain [IPR013106]	0.7525520620661418	2.100287432851567	0.0357035640946405	1.0	0.0885932505670403	2	Q92692	1
+U2A'/phosphoprotein 32 family A, C-terminal [IPR003603]	0.7468354430379731	2.0749636303675354	0.0379899056319141	1.0	0.0925534723637131	2	Q92688	1
+3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176]	0.7439771335238856	2.062275560467464	0.0391815084441766	1.0	0.0944485099269066	2	Q16836	1
+3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108]	0.7439771335238856	2.062275560467464	0.0391815084441766	1.0	0.0944485099269066	2	Q16836	1
+Damage-control phosphatase ARMT1-like, metal-binding domain [IPR002791]	0.7354022049816219	2.0241073064653974	0.0429591120127119	1.0	0.0993450543294221	2	Q9H993	1
+Dehydrogenase, E1 component [IPR001017]	0.7280522662311169	1.991268382618799	0.0464513894798468	1.0	0.1030376275734784	2	P08559	1
+ABC transporter type 1, transmembrane domain [IPR011527]	0.7341754219929819	1.975283167126748	0.0482360223909252	1.0	0.1058204846857861	6	P08183,P28288,O15439	3
+ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]	0.7178440179665128	1.9454722965743745	0.0517181608332939	1.0	0.1099448995062086	2	Q5T9A4	1
+Electron transfer flavoprotein, alpha/beta-subunit, N-terminal [IPR014730]	0.7092690894242561	1.9068384592724323	0.0565415093717622	1.0	0.114861382590555	2	P13804	1
+NOPS [IPR012975]	0.7042483660130728	1.8717660089358783	0.0612389827877137	1.0	0.1210448300646439	3	P23246,Q8WXF1	2
+Glutathione S-transferase, C-terminal-like [IPR010987]	0.7111250400660675	1.8576481190983989	0.0632190004751902	1.0	0.1230752881591469	9	P78417,O43708	2
+Peptidase M16, N-terminal [IPR011765]	0.7006020595260665	1.8167455568961075	0.0692560825834234	1.0	0.1317402185970305	7	P22695,P31930,Q10713,Q5JRX3	4
+Peptidase M16, C-terminal [IPR007863]	0.7006020595260665	1.8167455568961075	0.0692560825834234	1.0	0.1317402185970305	7	P22695,P31930,Q10713,Q5JRX3	4
+Immunoglobulin subtype [IPR003599]	0.695356369552814	1.7976243026955605	0.072236564434466	1.0	0.133866240926656	6	Q92692,P35613	2
+Peptidase M41 [IPR000642]	0.6794610044916269	1.771407932781292	0.0764928903909212	1.0	0.139285561607349	2	Q96TA2	1
+NADP-dependent oxidoreductase domain [IPR023210]	0.6801398210401446	1.7617076419891116	0.0781187060232944	1.0	0.1411923279235839	3	P14550	1
+Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]	0.6868441586746048	1.758278616964825	0.0787001141799614	1.0	0.1418928166988468	6	Q8IWA4	1
+Dynamin, N-terminal [IPR045063]	0.6868441586746048	1.758278616964825	0.0787001141799614	1.0	0.1418928166988468	6	Q8IWA4	1
+Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant [IPR000866]	0.6755210461789978	1.7280904919973243	0.0839720018660621	1.0	0.1476401249782805	4	P30048,Q13162,P30041	3
+Peroxiredoxin, C-terminal [IPR019479]	0.6755210461789978	1.7280904919973243	0.0839720018660621	1.0	0.1476401249782805	4	P30048,Q13162,P30041	3
+Armadillo repeat-containing domain [IPR006911]	0.6643527970600244	1.702128082720428	0.0887313605830109	1.0	0.1534283998742456	2	Q9UH62	1
+Immunoglobulin subtype 2 [IPR003598]	0.6655224218460114	1.670274086181614	0.0948651478063773	1.0	0.1592915964468224	5	P35613,Q9Y639,Q9Y624	3
+Helicase/SANT-associated domain [IPR014012]	0.6545528787260116	1.656976578146652	0.097524210525784	1.0	0.1627379683241807	2	Q6ZRS2	1
+Immunoglobulin I-set [IPR013098]	0.647611269906083	1.624898165353023	0.1041842591997039	1.0	0.1713262684198334	2	Q13308	1
+Intermediate filament head, DNA-binding domain [IPR006821]	0.6529277229151649	1.6234213194081073	0.1044993703189756	1.0	0.1713820890369458	4	Q16352,P07197	2
+PWI domain [IPR002483]	0.6504905543261411	1.600214312383439	0.1095510481329562	1.0	0.1761682929745554	5	Q5T8P6	1
+NAD-dependent epimerase/dehydratase [IPR001509]	0.64179923709238	1.5845410131420803	0.1130706561838632	1.0	0.1791509097978093	3	Q16795	1
+OCRE domain [IPR041591]	0.6365863617803167	1.5737955630696576	0.1155347201575824	1.0	0.1821668521657438	2	P98175	1
+Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding [IPR013155]	0.6446701922835852	1.5615043472769512	0.1184047989266958	1.0	0.1853292504939587	6	Q9NSE4,Q5ST30	2
+Aminoacyl-tRNA synthetase, class Ia [IPR002300]	0.6446701922835852	1.5615043472769512	0.1184047989266958	1.0	0.1853292504939587	6	Q9NSE4,Q5ST30	2
+Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain [IPR014038]	0.6218864842792937	1.505387550635581	0.1322244678875042	1.0	0.2005282675973475	2	P24534	1
+Elongation factor 1 beta central acidic region, eukaryote [IPR018940]	0.6218864842792937	1.505387550635581	0.1322244678875042	1.0	0.2005282675973475	2	P24534	1
+Alanyl-tRNA synthetase, class IIc, core domain [IPR018165]	0.6181416148415128	1.4741098700901965	0.1404520114655034	1.0	0.2084004170123281	3	Q9BTE6	1
+Far upstream element-binding protein, C-terminal [IPR015096]	0.6124948958758651	1.461537611246491	0.1438679616455331	1.0	0.2120362709889871	2	Q96AE4	1
+RNA recognition motif domain [IPR000504]	0.3682223478563283	1.4598795254266352	0.1443231872417063	1.0	0.2122934985180032	103	P07910,Q5T8P6,P62995,P38159,O43390,P31483,P35637,P31942,O14979,P55795,P09651,Q14011,Q96EP5,Q12849,Q01844,P22626,Q96PK6,P31943,Q99729,Q8WUA2,P23246,Q8IY67,Q8WXF1,O60506,Q14103,Q86U42,Q76FK4,Q01085,P52597,Q92804,Q13243,Q96DH6,Q16630,Q13151,Q14151	35
+Survival motor neuron [IPR010304]	0.6047366271947705	1.425239174628308	0.1540880758816714	1.0	0.2223241883286139	2	Q16637	1
+Staufen, C-terminal [IPR032478]	0.6039199673336022	1.4214147076334191	0.15519623323259	1.0	0.2226888027193408	2	Q9NUL3	1
+Aldehyde dehydrogenase domain [IPR015590]	0.6172891797348191	1.4130405995562048	0.1576437869839395	1.0	0.2249420118367324	9	O94788,P49419	2
+Ribosomal protein S10 domain [IPR027486]	0.6002449979583473	1.4041967622799614	0.1602602657309817	1.0	0.2270526087388618	2	Q96GC5	1
+B-box, C-terminal [IPR003649]	0.6010009413614377	1.3936878599643978	0.1634118838003782	1.0	0.2295472992253329	3	O15344	1
+RING-type zinc-finger, LisH dimerisation motif [IPR027370]	0.6010009413614377	1.3936878599643978	0.1634118838003782	1.0	0.2295472992253329	3	O15344	1
+ABC transporter-like, ATP-binding domain [IPR003439]	0.6089037521182123	1.3727428234531878	0.1698323112564712	1.0	0.2351524309704986	9	P08183,P28288,O15439	3
+Gamma tubulin complex component, C-terminal [IPR040457]	0.5920783993466685	1.3658925108898583	0.1719727037114209	1.0	0.2363279457761454	2	Q96CW5	1
+Gamma tubulin complex component protein, N-terminal [IPR041470]	0.5920783993466685	1.3658925108898583	0.1719727037114209	1.0	0.2363279457761454	2	Q96CW5	1
+Reticulon [IPR003388]	0.5908534095549167	1.3601423448077232	0.1737848832994186	1.0	0.2380733647695092	2	O95197	1
+Dynamin GTPase effector [IPR003130]	0.5863617803184937	1.3390495075228492	0.1805545564699631	1.0	0.2453627349166411	2	P50570	1
+GTPase effector domain [IPR020850]	0.5863617803184937	1.3390495075228492	0.1805545564699631	1.0	0.2453627349166411	2	P50570	1
+Dynamin stalk domain [IPR000375]	0.5863617803184937	1.3390495075228492	0.1805545564699631	1.0	0.2453627349166411	2	P50570	1
+Dynamin, GTPase domain [IPR001401]	0.5866013071895438	1.3259303939973714	0.1848627543395167	1.0	0.2489016606557809	3	O60313,P50570	2
+Band 7 domain [IPR001107]	0.5899822718688765	1.302873539197592	0.1926179390396716	1.0	0.2557086450800165	6	Q9UJZ1,O94905	2
+ERAP1-like C-terminal domain [IPR024571]	0.5834833986564567	1.297405612932692	0.194491662268192	1.0	0.2570885606636012	4	Q9NZ08	1
+PABP, RNA recognition motif 2 [IPR045305]	0.5581870151082026	1.2065406250451405	0.2276091047528896	1.0	0.2890859421846996	2	P11940	1
+Polyadenylate-binding protein/Hyperplastic disc protein [IPR002004]	0.5584150326797399	1.1930396398570406	0.2328538489188698	1.0	0.2938776162217461	3	O95071,P11940	2
+Major sperm protein (MSP) domain [IPR000535]	0.5516537362188597	1.175802965990304	0.2396736209056733	1.0	0.3007561551479192	2	O95292	1
+Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain [IPR001030]	0.5365455287872543	1.104787272710399	0.2692517766419091	1.0	0.3270336844610799	2	P21399	1
+Aconitase A/isopropylmalate dehydratase small subunit, swivel domain [IPR000573]	0.5365455287872543	1.104787272710399	0.2692517766419091	1.0	0.3270336844610799	2	P21399	1
+Hotdog acyl-CoA thioesterase (ACOT)-type domain [IPR033120]	0.5287872601061636	1.0683852165916556	0.2853467827851355	1.0	0.3407403670452189	2	O00154	1
+Aminopeptidase N-like , N-terminal domain [IPR045357]	0.5336873151963373	1.0355953342365738	0.3003909696002385	1.0	0.3523817143387413	6	Q9NZ08	1
+Peptidase M1, membrane alanine aminopeptidase [IPR014782]	0.5336873151963373	1.0355953342365738	0.3003909696002385	1.0	0.3523817143387413	6	Q9NZ08	1
+Proteasome alpha-subunit, N-terminal domain [IPR000426]	0.5317277061924792	1.0175134315231489	0.3089092459826554	1.0	0.3596843606457642	7	P60900,P25789,P25787	3
+LEM-like domain [IPR013146]	0.5153123723968911	1.005333232420155	0.3147364180672287	1.0	0.364277176848056	2	P42166	1
+AP complex, mu/sigma subunit [IPR022775]	0.5236753168164229	1.0015222519905886	0.3165743877355038	1.0	0.3655085990889413	5	Q92572	1
+Heat shock protein Hsp90, N-terminal [IPR020575]	0.5134005447892619	0.9669887856404498	0.3335496398157915	1.0	0.3783445294604743	4	Q12931	1
+Cullin, N-terminal [IPR001373]	0.5119796525921572	0.9333935648176866	0.3506168017572411	1.0	0.3896530853536951	6	Q13619	1
+Cullin protein, neddylation domain [IPR019559]	0.5119796525921572	0.9333935648176866	0.3506168017572411	1.0	0.3896530853536951	6	Q13619	1
+Cullin homology domain [IPR016158]	0.5119796525921572	0.9333935648176866	0.3506168017572411	1.0	0.3896530853536951	6	Q13619	1
+Threonyl/alanyl tRNA synthetase, SAD [IPR012947]	0.5042689773338689	0.9106569527322514	0.3624761521903283	1.0	0.4018160677485922	5	Q9BTE6,Q9BW92	2
+Ribose-phosphate pyrophosphokinase, N-terminal domain [IPR029099]	0.4924458962841951	0.8991116982225957	0.3685931676488372	1.0	0.4076955822017442	2	Q14558	1
+Immunoglobulin-like domain [IPR007110]	0.5061972631752011	0.88010416683695	0.3788028820534586	1.0	0.4167590826600175	9	P35613,Q92692,Q9Y639,P10321,Q9Y624	5
+Thioesterase domain [IPR006683]	0.4740710494079188	0.8148237792973771	0.4151731874057525	1.0	0.4517940136486781	2	O00154	1
+GTP binding protein, second domain [IPR031662]	0.4728460596161671	0.8092485417702694	0.4183721986165338	1.0	0.4550497019127827	2	P55039	1
+Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091]	0.4808916416948443	0.7796503361604166	0.4355967188901259	1.0	0.4716816541827991	7	Q15067,Q9H845,P49748	3
+L27 domain [IPR004172]	0.4503879134340525	0.7082648775260184	0.4787807838217555	1.0	0.5154566955225031	2	Q14168	1
+L27 domain, C-terminal [IPR014775]	0.4503879134340525	0.7082648775260184	0.4787807838217555	1.0	0.5154566955225031	2	Q14168	1
+EB1, C-terminal [IPR004953]	0.4458962841976313	0.6883906682489803	0.4912067987274837	1.0	0.5282517776716721	2	Q15691	1
+Importin-beta, N-terminal domain [IPR001494]	0.4657761869315621	0.669002536001208	0.5034938602459924	1.0	0.5406711575062099	12	Q9UI26,Q92973,Q9HAV4,P55060,Q8TEX9,O15397	6
+Lamin tail domain [IPR001322]	0.4415849673202634	0.6546775051021289	0.5126754113467122	1.0	0.5502615851991105	3	Q03252,P02545	2
+Legume-like lectin [IPR005052]	0.4360963658636156	0.6454714731994174	0.5186216989848362	1.0	0.5561002202005373	2	P49257	1
+Zinc finger, RanBP2-type [IPR001876]	0.4537439459264765	0.6386381484532705	0.5230583581571935	1.0	0.5603103192747302	9	Q92804	1
+Chromo shadow domain [IPR008251]	0.4354575163398712	0.6280145119693032	0.5299944333917368	1.0	0.5671870252087008	3	P45973,P83916	2
+Chromo domain subgroup [IPR017984]	0.4354575163398712	0.6280145119693032	0.5299944333917368	1.0	0.5671870252087008	3	P45973,P83916	2
+RecF/RecN/SMC, N-terminal [IPR003395]	0.4390842191332912	0.6158146145498614	0.5380168806991972	1.0	0.5754919970849669	5	Q9NTJ3,Q14683,Q9UQE7,Q96SB8	4
+SWIRM domain [IPR007526]	0.432588266005838	0.6013738831850866	0.5475909897146614	1.0	0.5854478156832504	4	Q8TAQ2	1
+Histidine kinase/HSP90-like ATPase [IPR003594]	0.439411335073497	0.59410028628857	0.5524450394200424	1.0	0.5894894589729899	7	Q12931,Q15120	2
+Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain [IPR020631]	0.41544117647059	0.5429616420089433	0.5871562128218326	1.0	0.624404379349513	3	Q6UB35,P13995	2
+Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain [IPR020630]	0.41544117647059	0.5429616420089433	0.5871562128218326	1.0	0.624404379349513	3	Q6UB35,P13995	2
+AGC-kinase, C-terminal [IPR000961]	0.4237956447137539	0.5374299815226864	0.5909706381788598	1.0	0.6281565931465518	6	P17612,P31751,O75116	3
+Glutamine amidotransferase [IPR017926]	0.4169891318753628	0.5354085647347584	0.5923673689655287	1.0	0.6293365951854383	4	P17812	1
+14-3-3 domain [IPR023410]	0.4201176599857195	0.5220706863461481	0.6016211154777547	1.0	0.6382415312024875	6	P62258,P61981,P27348	3
+Ran binding domain [IPR000156]	0.4119329791581609	0.5145049198047331	0.6068990215880596	1.0	0.6425989640344161	4	Q9H6Z4,Q9UKX7,P43487	3
+Ubiquitin-associated domain [IPR015940]	0.4202103210100602	0.4939285648841628	0.6213566302476512	1.0	0.6569567453172085	9	P54727,Q9NRR5	2
+DnaJ domain [IPR001623]	0.4250133907400686	0.4746035824395788	0.6350695523434211	1.0	0.6711322121973786	14	Q9UGP8,Q8IXB1,O75937,Q13217	4
+S-adenosyl-L-homocysteine hydrolase, NAD binding domain [IPR015878]	0.3911800734993892	0.4587893859096472	0.6463854175726915	1.0	0.6827620860940984	2	O43865	1
+Death domain [IPR000488]	0.3876633986928126	0.4313263308022428	0.666231107444679	1.0	0.6990174447914549	3	Q96FV9,Q13546	2
+Intermediate filament, rod domain [IPR039008]	0.4008299572499622	0.4245479074629365	0.6711662745008355	1.0	0.7038591875854036	8	Q16352,P07197	2
+EF-hand domain [IPR002048]	0.4190724341131407	0.4059320232875132	0.6847925477723376	1.0	0.7164385111520025	37	Q9Y680,Q02818,Q9UJS0,P30626,Q03001,O75746,P80303,O95202,Q6NUK1,O75340,Q96AY3,Q8IXI2,Q9NWM8,P43304	14
+Class II aldolase/adducin N-terminal [IPR001303]	0.3752552062066163	0.3977349700342805	0.6908255571301898	1.0	0.7224061540275699	2	P35611	1
+Mu homology domain [IPR028565]	0.3735185941969768	0.3650994578459739	0.71503716559259	1.0	0.7463030492591861	4	Q9BXS5,P48444,Q96CW1	3
+Deoxynucleoside kinase domain [IPR031314]	0.3564720293997593	0.3301439148944272	0.7412912224122623	1.0	0.7700451865739489	2	O95299	1
+Translation elongation factor EFG/EF2, domain IV [IPR005517]	0.3553921568627473	0.3138161916658077	0.7536606460054769	1.0	0.7817849686480998	3	P13639,Q96RP9	2
+Elongation Factor G, domain II [IPR041095]	0.3555373927257872	0.3020573259535631	0.7626083628042297	1.0	0.7895747122668969	4	Q7Z2Z2,P13639,Q96RP9	3
+Elongation factor EFG, domain V-like [IPR000640]	0.3555373927257872	0.3020573259535631	0.7626083628042297	1.0	0.7895747122668969	4	Q7Z2Z2,P13639,Q96RP9	3
+TGS [IPR004095]	0.3426576252548143	0.2380392353885672	0.8118506632248603	1.0	0.8358293747969026	6	Q9BW92	1
+CS domain [IPR007052]	0.3450511280290531	0.2278532813610121	0.8197603034277865	1.0	0.8435771444833267	8	Q9HB71,Q8WVJ2,Q15185,Q9P035,Q9Y266	5
+K Homology domain [IPR004087]	0.3718790621115012	0.2218478654304709	0.8244323165191532	1.0	0.8464017611388781	22	Q96PU8,Q9NRX1	2
+CSN8/PSMD8/EIF3K [IPR033464]	0.3223039215686296	0.2107048567646504	0.8331175845391883	1.0	0.8549187923589053	3	P48556,Q99627	2
+NECAP, PHear domain [IPR012466]	0.3070641077991087	0.1804207990971347	0.8568222269313752	1.0	0.8776033630323227	2	Q9NVZ3	1
+Transketolase-like, pyrimidine-binding domain [IPR005475]	0.3097156979469504	0.176847276615309	0.8596283528948354	1.0	0.8800670689776496	3	P11177	1
+Phosphoribosyltransferase domain [IPR000836]	0.3172526573998483	0.1761563590044336	0.8601711050432674	1.0	0.8802123703052261	5	P07741,O60256,Q06203,P11172	4
+Proteasome activator PA28, C-terminal domain [IPR003186]	0.3088235294117669	0.1745674738473799	0.8614195081946561	1.0	0.8802916571156165	3	Q9UL46,Q06323	2
+Proteasome activator PA28, N-terminal domain [IPR003185]	0.3088235294117669	0.1745674738473799	0.8614195081946561	1.0	0.8802916571156165	3	Q9UL46,Q06323	2
+Ubiquitin-like domain [IPR000626]	0.3240092612803047	0.1450513167773965	0.8846703552548478	1.0	0.8989842115850373	11	Q9NRR5	1
+RNA recognition motif domain, eukaryote [IPR003954]	0.3237037813381554	0.137189820791353	0.8908807566663433	1.0	0.9036370169234594	12	P31483,P38159	2
+FCP1 homology domain [IPR004274]	0.2866476112699104	0.1323318581002374	0.894721809831011	1.0	0.9041919440353888	2	Q05D32	1
+Tyrosine-protein kinase, catalytic domain [IPR020635]	0.2862392813393266	0.1314581560350829	0.8954128858983212	1.0	0.904474101854974	2	P41240	1
+Aminotransferase, class I/classII [IPR004839]	0.2923251294270426	0.1173028789713082	0.9066200436941336	1.0	0.9153736165298012	5	P17174	1
+Rab-GTPase-TBC domain [IPR000195]	0.2959550427151682	0.116320548294364	0.9073985009697508	1.0	0.9157385607213108	6	Q4KMP7	1
+RNA-binding domain, S1 [IPR022967]	0.2876432078559763	0.092229705982129	0.9265155366634488	1.0	0.9333156506940062	7	P05198,Q14690,Q8TCS8,Q9Y3B2,P62487,Q14562	6
+SCP2 sterol-binding domain [IPR003033]	0.2638888888888914	0.0810242270199848	0.9354226854691876	1.0	0.9418561289731022	3	P51659,P22307	2
+AAA+ ATPase domain [IPR003593]	0.3348888622723162	0.0677832264761722	0.9459581963821042	1.0	0.952027589026169	46	P40938,P35251,O75027,Q9BSD7,P28288,P06576,P08183,O15439,P35250	9
+PDZ domain [IPR001478]	0.2940113809079048	0.0650723301921253	0.9481164110342116	1.0	0.9537625463266738	13	O43464	1
+Anticodon-binding [IPR004154]	0.2533714752758508	0.0580023069151002	0.9537467909698788	1.0	0.9587962071526775	4	Q9BW92,P26639,P41250	3
+Prolyl 4-hydroxylase, alpha subunit [IPR006620]	0.2661614414687979	0.0558204257099158	0.955484862948606	1.0	0.9594168994216457	7	O15460	1
+Oxoglutarate/iron-dependent dioxygenase [IPR005123]	0.2661614414687979	0.0558204257099158	0.955484862948606	1.0	0.9594168994216457	7	O15460	1
+Aminoacyl-tRNA synthetase, class II [IPR006195]	0.2441249949639098	0.0069598141536824	0.9944469165717358	1.0	0.9971714286719324	11	Q6PI48,Q9NP81	2

interpro_family/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_family/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Proteasome, subunit alpha/beta [IPR001353]", "1": "Heat shock protein 70 family [IPR013126]"}

interpro_family/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:55e177c2fb5fdc89ddbce32fff1c3cf6c5307b485563b4e419eeec075448bf9d
+size 496749