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- interpro_active_site/advanced/idx2term.json +1 -0
- interpro_active_site/basic/idx2term.json +1 -0
- interpro_active_site/consensus.joblib +3 -0
- interpro_active_site/df_merge.tsv +1 -0
- interpro_active_site/metrics.json +7 -0
- interpro_active_site/paths.json +1 -0
- interpro_active_site/result.tsv +4 -0
- interpro_active_site/selections.json +1 -0
- interpro_binding_site/advanced/idx2term.json +1 -0
- interpro_binding_site/basic/idx2term.json +1 -0
- interpro_binding_site/basic/plot_0.png +3 -0
- interpro_binding_site/consensus.joblib +3 -0
- interpro_binding_site/df_merge.tsv +1 -0
- interpro_binding_site/metrics.json +7 -0
- interpro_binding_site/paths.json +1 -0
- interpro_binding_site/result.tsv +5 -0
- interpro_binding_site/selections.json +1 -0
- interpro_conserved_site/advanced/idx2term.json +1 -0
- interpro_conserved_site/advanced/plot_0.png +3 -0
- interpro_conserved_site/basic/idx2term.json +1 -0
- interpro_conserved_site/basic/plot_0.png +3 -0
- interpro_conserved_site/consensus.joblib +3 -0
- interpro_conserved_site/df_merge.tsv +2 -0
- interpro_conserved_site/metrics.json +7 -0
- interpro_conserved_site/paths.json +1 -0
- interpro_conserved_site/result.tsv +25 -0
- interpro_conserved_site/selections.json +1 -0
- interpro_domain/advanced/idx2term.json +1 -0
- interpro_domain/advanced/plot_0.png +3 -0
- interpro_domain/advanced/plot_1.png +3 -0
- interpro_domain/basic/idx2term.json +1 -0
- interpro_domain/basic/plot_0.png +3 -0
- interpro_domain/basic/plot_1.png +3 -0
- interpro_domain/basic/plot_2.png +3 -0
- interpro_domain/basic/plot_3.png +3 -0
- interpro_domain/consensus.joblib +3 -0
- interpro_domain/df_merge.tsv +4 -0
- interpro_domain/metrics.json +7 -0
- interpro_domain/paths.json +1 -0
- interpro_domain/result.tsv +151 -0
- interpro_domain/selections.json +0 -0
- interpro_family/advanced/idx2term.json +1 -0
- interpro_family/advanced/plot_0.png +3 -0
- interpro_family/basic/idx2term.json +1 -0
- interpro_family/basic/plot_0.png +3 -0
- interpro_family/basic/plot_1.png +3 -0
- interpro_family/consensus.joblib +3 -0
- interpro_family/df_merge.tsv +3 -0
- interpro_family/metrics.json +7 -0
- interpro_family/paths.json +1 -0
interpro_active_site/advanced/idx2term.json
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{}
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interpro_active_site/basic/idx2term.json
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{}
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interpro_active_site/consensus.joblib
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version https://git-lfs.github.com/spec/v1
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oid sha256:6567eee94f3dd49b547a108e9a65cb310f3f1d05dca27d1b30d87bd818d829f5
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size 57175
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interpro_active_site/df_merge.tsv
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term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
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interpro_active_site/metrics.json
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{
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"type_of_task": "ranksum",
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"signature_size": 2454,
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"annotations_size": 50,
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"title": "Average number of proteins per term",
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"value": 2.3
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}
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interpro_active_site/paths.json
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{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C339/C339_val_log2fc"}
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interpro_active_site/result.tsv
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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
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Serine carboxypeptidase, serine active site [IPR018202] 0.813137494900046 1.3888489774549162 0.1648786783792448 0.9998776853171628 0.4121966959481121 3 Q9H3G5,Q9HB40 2
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Histidine acid phosphatase active site [IPR033379] 0.9355628058727576 1.1604858515014065 0.2458510509126139 0.9999992537978268 0.5344588063317695 2 P11117 1
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ATP:guanido phosphotransferase active site [IPR022415] 0.6252039151712943 0.2037260666897278 0.8385675710927558 1.0 0.917648250082921 2 P12277 1
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interpro_active_site/selections.json
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{"all_annotations": ["ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Cysteine peptidase, cysteine active site [IPR000169]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADSS", "AKT2", "APEH", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "BLMH", "CAMK2D", "CAMK2G", "CAPN1", "CAPN2", "CDC34", "CDK1", "CDK12", "CDK2", "CDK4", "CDK5", "CDK6", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CTSA", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLUD1", "GSK3A", "GSK3B", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "LDHA", "LDHB", "LONP1", "MAP2K1", "MARK2", "MDH1", "MDH2", "MTMR6", "NEK9", "NME1", "PAK2", "PBK", "PGAM1", "PKM", "PKN2", "PLK1", "PREP", "PRKACA", "PRPF4B", "PTK7", "PTPN1", "RIPK1", "RNASET2", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TPI1", "TPP2", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UMPS", "UNG", "VRK1"], "leading_proteins": ["ACP2", "CKB", "CPVL", "SCPEP1"]}
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interpro_binding_site/advanced/idx2term.json
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interpro_binding_site/basic/idx2term.json
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{"0": "EF-Hand 1, calcium-binding site [IPR018247]"}
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interpro_binding_site/basic/plot_0.png
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interpro_binding_site/consensus.joblib
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version https://git-lfs.github.com/spec/v1
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oid sha256:f06e8fe1bb28ab10a467b1cc3401e0a0f4e6a5d435515c733f0b80b21830c518
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interpro_binding_site/df_merge.tsv
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term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
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interpro_binding_site/metrics.json
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{
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"type_of_task": "ranksum",
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"signature_size": 2454,
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"annotations_size": 27,
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"title": "Average number of proteins per term",
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"value": 4.111111111111111
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}
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interpro_binding_site/paths.json
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{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C339/C339_val_log2fc"}
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interpro_binding_site/result.tsv
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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
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Peptidase M16, zinc-binding site [IPR001431] 0.7438715542492007 1.73157401788584 0.0833494355927677 0.9046099942568666 0.2974107662141101 5 O43847,Q10713 2
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Beta tubulin, autoregulation binding site [IPR013838] 0.7763305582305653 1.5945134563000507 0.1108210792636814 0.9580523842115964 0.2974107662141101 4 P07437,P68371 2
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EF-Hand 1, calcium-binding site [IPR018247] 0.4068231231365906 0.7487552859249842 0.4540047145867039 0.9999999198137136 0.8172084862560669 32 Q96D71,Q14257,P80303,Q9Y680,Q9NWM8,Q02818,O95202 7
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Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798] 0.5848287112561251 0.1354936109374344 0.8922216154101594 1.0 0.963599344642972 2 P34896 1
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interpro_binding_site/selections.json
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{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Protein kinase, ATP binding site [IPR017441]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "ARG2", "CALU", "CAMK2D", "CAMK2G", "CAPN1", "CAPN2", "CDK1", "CDK12", "CDK2", "CDK4", "CDK5", "CDK6", "COX2", "COX5B", "CSK", "CSNK1A1", "CYB5B", "DLAT", "DLST", "DST", "EHD1", "EIF2AK2", "EPHA7", "FKBP10", "FKBP14", "FKBP7", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "GSK3B", "HK1", "HK2", "IDE", "ILKAP", "IQGAP1", "LETM1", "MACF1", "MAP2K1", "MARK2", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1C", "NRDC", "NUCB1", "NUCB2", "PA2G4", "PAK2", "PAK4", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKN2", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "PPM1G", "PRKACA", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SRI", "SRPK1", "SRPK2", "TKT", "TTK", "TUBB", "TUBB2B", "TUBB4B", "TUBB6", "UBE3C", "UQCRC2", "VRK1"], "leading_proteins": ["FKBP14", "FKBP7", "LETM1", "NRDC", "NUCB1", "NUCB2", "PMPCA", "RCN2", "REPS1", "SHMT1", "TUBB", "TUBB4B"]}
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interpro_conserved_site/advanced/idx2term.json
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{"0": "Intermediate filament protein, conserved site [IPR018039]"}
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interpro_conserved_site/advanced/plot_0.png
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interpro_conserved_site/basic/idx2term.json
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{"0": "Intermediate filament protein, conserved site [IPR018039]"}
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interpro_conserved_site/basic/plot_0.png
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interpro_conserved_site/consensus.joblib
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version https://git-lfs.github.com/spec/v1
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oid sha256:50e16d7834d414dbf2f50c964018c3ba8651476d67f2e342fee1be5d62401ef1
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size 63581
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interpro_conserved_site/df_merge.tsv
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term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
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Intermediate filament protein, conserved site [IPR018039] 5 8 2.097975342352379 0.0359073236171256 4.060679611650485 7.546116504854369 0.7869831563787604 0.2926647109331939 1.9153715257926656 0.8924219614624045 1.3691577499316503 0.3120813432784052 0.0520323050894142 1.0 1.0 0.0693365470158766 0.0013491401517078
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interpro_conserved_site/metrics.json
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{
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"type_of_task": "ranksum",
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"signature_size": 2454,
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"annotations_size": 252,
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"title": "Average number of proteins per term",
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"value": 2.488095238095238
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}
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interpro_conserved_site/paths.json
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{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C339/C339_val_log2fc"}
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interpro_conserved_site/result.tsv
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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
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Intermediate filament protein, conserved site [IPR018039] 0.7133190377454319 2.097975342352379 0.0359073236171256 0.9999004746945293 0.5060229969032058 8 P02545,P07197,Q16352,P08670,P20700 5
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Mini-chromosome maintenance, conserved site [IPR018525] 0.7698621903137278 1.774776583449412 0.075934784266697 0.9999999977245836 0.5060229969032058 6 Q14566 1
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ABC transporter-like, conserved site [IPR017871] 0.6322265803532345 1.6694351751606211 0.095031167447805 0.9999999999882055 0.5206055260184103 9 P08183,P28288,Q03519 3
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Tubulin, conserved site [IPR017975] 0.7763305582305653 1.5945134563000507 0.1108210792636814 0.9999999999998602 0.545153542069468 4 P07437,P68371 2
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Syntaxin/epimorphin, conserved site [IPR006012] 0.8531211750306023 1.551242016238065 0.120843696587372 0.999999999999992 0.5737436942807838 3 O15400,Q9P2W9 2
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Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364] 0.7505700607004644 1.4844211287270372 0.1376972328770982 1.0 0.5755257456069881 4 Q8N4Q0,Q8WWV3 2
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Haem oxygenase conserved site [IPR018207] 0.9910277324632952 1.3673940858356175 0.1715018150979992 1.0 0.6331686147844477 2 P09601 1
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Sterol reductase, conserved site [IPR018083] 0.9180261011419202 1.0956955702646416 0.2732120219034382 1.0 0.6916946972626963 2 Q14739 1
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Thioredoxin, conserved site [IPR017937] 0.500630173691376 0.9515269601001126 0.3413369393091461 1.0 0.7344079902332534 10 Q9H1E5 1
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| 11 |
+
Aldehyde dehydrogenase, cysteine active site [IPR016160] 0.5393184811848324 0.940806999712476 0.346803773165703 1.0 0.7344079902332534 7 P51648 1
|
| 12 |
+
Short-chain dehydrogenase/reductase, conserved site [IPR020904] 0.4700583172838378 0.7969752093663556 0.4254654291852613 1.0 0.7883624129021019 9 Q53GQ0,Q06136 2
|
| 13 |
+
Proteasome beta-type subunit, conserved site [IPR016050] 0.4499839769692626 0.7016879973416201 0.4828737598834687 1.0 0.8098310652469046 8 P28072,P49721 2
|
| 14 |
+
Guanylate kinase, conserved site [IPR020590] 0.7838499184339313 0.6249400371930515 0.5320104137404442 1.0 0.8327119519415649 2 Q14168 1
|
| 15 |
+
HMG box A DNA-binding domain, conserved site [IPR017967] 0.5875152998776041 0.5108332573354828 0.6094678193292917 1.0 0.9034464145351854 3 P26583,P09429 2
|
| 16 |
+
3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180] 0.7243066884176215 0.4425007938027191 0.6581268560062175 1.0 0.9062730476151192 2 P40939 1
|
| 17 |
+
Dynamin, GTPase region, conserved site [IPR019762] 0.7063621533442092 0.3925383415234369 0.6946604874360323 1.0 0.9213391728098954 2 P50570 1
|
| 18 |
+
Chromo domain, conserved site [IPR023779] 0.5291717666258624 0.3256734742031772 0.7446714155209861 1.0 0.9399274340311792 3 P45973,P83916 2
|
| 19 |
+
Aldehyde dehydrogenase, glutamic acid active site [IPR029510] 0.3970528247286624 0.2795175204662965 0.779847694248639 1.0 0.9460923602182884 7 P51648 1
|
| 20 |
+
Ribosomal protein L30, conserved site [IPR018038] 0.6427406199021238 0.2388858022831277 0.8111941350194818 1.0 0.9463931575227288 2 Q6DKI1 1
|
| 21 |
+
Actin, conserved site [IPR004001] 0.4577723378213035 0.151059404789691 0.8799288552380311 1.0 0.9516827103861968 3 O96019,P61163 2
|
| 22 |
+
AMP-binding, conserved site [IPR020845] 0.3511637403021673 0.0975097074351722 0.9223216255500576 1.0 0.9848519052483664 5 O60488,O95573,Q6P1M0,P33121 4
|
| 23 |
+
Adenylate kinase, conserved site [IPR033690] 0.4120767033863808 0.0754104119491569 0.9398881752622938 1.0 0.9928729786643924 3 P00568,P54819 2
|
| 24 |
+
Ribosomal protein S5, N-terminal, conserved site [IPR018192] 0.5326264274062078 0.0731919893354346 0.9416533408761498 1.0 0.9928729786643924 2 P82675 1
|
| 25 |
+
Ribosomal S11, conserved site [IPR018102] 0.4955138662316604 0.0448237910352104 0.9642477616445266 1.0 0.9958624423541832 2 P82912 1
|
interpro_conserved_site/selections.json
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{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Amyloidogenic glycoprotein, copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Bromodomain, conserved site [IPR018359]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Homeobox, conserved site [IPR017970]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RIO kinase, conserved site [IPR018935]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]"], "available_proteins": ["AAAS", "ABCB1", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ACAA2", "ACAD9", "ACADM", "ACADS", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR1B", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP3M1", "AP3S1", "APEX1", "APLP2", "APP", "ARIH2", "ATAD1", "ATP5C1", "ATP5O", "BAG6", "BAZ1A", "BAZ1B", "BAZ2A", "BCAT2", "BLM", "BOP1", "BPTF", "BRCA1", "BRD2", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CBR1", "CBX1", "CBX3", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDKAL1", "CECR2", "CHAF1B", "CHD4", "CLGN", "CMPK1", "CNDP2", "COPA", "COPZ1", "CORO1B", "CORO1C", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX6", "DHCR7", "DHFR", "DHRS7", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX40", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DRG1", "DRG2", "DSG2", "DST", "DTYMK", "DYNLL1", "ECH1", "ECHS1", "ECI2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "ENO1", "EPB41", "EPB41L2", "EPHA7", "EPRS", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXC1", "FOXK1", "FUCA2", "GAA", "GALK1", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLO1", "GMPPA", "GNPDA1", "GNS", "GPI", "GRHPR", "GRWD1", "GSPT1", "GTF3C2", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HOXA10", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "ILVBL", "IMPDH2", "INA", "IQGAP1", "IVD", "KDM2A", "KDSR", "KIF11", "KIF14", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LARS", "LARS2", "LBR", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGST2", "MID1", "MIF", "MPI", "MPP2", "MPP6", "MPST", "MRPL24", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFV1", "NEFL", "NEFM", "NES", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD2", "NSF", "NUBP2", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL6", "OSBPL9", "P4HB", "PAFAH1B1", "PAICS", "PBRM1", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHGDH", "PHIP", "PI4KB", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PNP", "PNPLA6", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2E", "PPIB", "PPIC", "PPID", "PPIF", "PPIG", "PPIH", "PPIL1", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RCL1", "RDH13", "RDX", "RECQL5", "RIOK2", "RNF114", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RTN4IP1", "S100A10", "S100A11", "SART1", "SBDS", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC27A4", "SLIT2", "SMARCA4", "SMU1", "SNRNP40", "SNU13", "SPATA5", "SPTBN1", "SRCAP", "SRM", "STMN1", "STRN4", "STX12", "STX18", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SYNE2", "TAP1", "TAP2", "TBL3", "TCP1", "THOC6", "TK1", "TLN1", "TMX1", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TSFM", "TSPAN6", "TUBB", "TUBB2B", "TUBB4B", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UHRF1", "USP10", "USP14", "USP36", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4B", "WARS", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR36", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2"], "leading_proteins": ["ABCB1", "ABCD3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTR1A", "AK1", "AK2", "ALDH3A2", "CBX1", "CBX5", "DNM2", "HADHA", "HMGB1", "HMGB2", "HMOX1", "HSD17B12", "INA", "KDSR", "LBR", "LMNA", "LMNB1", "MCM6", "MPP2", "MRPS11", "MRPS5", "NEFM", "PSMB2", "PSMB6", "RPL7L1", "RTN4IP1", "SLC27A4", "STX18", "STX7", "TAP2", "TMX4", "TUBB", "TUBB4B", "VIM", "ZADH2"]}
|
interpro_domain/advanced/idx2term.json
ADDED
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@@ -0,0 +1 @@
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| 1 |
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{"0": "Cytochrome b5-like heme/steroid binding domain [IPR001199]", "1": "Intermediate filament, rod domain [IPR039008]"}
|
interpro_domain/advanced/plot_0.png
ADDED
|
Git LFS Details
|
interpro_domain/advanced/plot_1.png
ADDED
|
Git LFS Details
|
interpro_domain/basic/idx2term.json
ADDED
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@@ -0,0 +1 @@
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| 1 |
+
{"0": "Cytochrome b5-like heme/steroid binding domain [IPR001199]", "1": "Intermediate filament, rod domain [IPR039008]", "2": "Band 7 domain [IPR001107]", "3": "EF-hand domain [IPR002048]"}
|
interpro_domain/basic/plot_0.png
ADDED
|
Git LFS Details
|
interpro_domain/basic/plot_1.png
ADDED
|
Git LFS Details
|
interpro_domain/basic/plot_2.png
ADDED
|
Git LFS Details
|
interpro_domain/basic/plot_3.png
ADDED
|
Git LFS Details
|
interpro_domain/consensus.joblib
ADDED
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| 1 |
+
version https://git-lfs.github.com/spec/v1
|
| 2 |
+
oid sha256:74318d4a6b90a692dab1d15265780a22cd0f5bb29eb93d2128dfd972fc0695b5
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| 3 |
+
size 130252
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interpro_domain/df_merge.tsv
ADDED
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term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
|
| 2 |
+
P-type ATPase, haloacid dehalogenase domain [IPR044492] 4 5 2.1673105884219037 0.0302111796747526 2.941747572815534 6.145631067961165 0.9567723497044874 0.2732808833570771 1.8358630293390923 1.459204245106796 1.2102525517005158 0.2943240638910574 0.074492189381682 1.0 0.191600110602388 0.0153906222854723 0.0035298468720628
|
| 3 |
+
Cytochrome b5-like heme/steroid binding domain [IPR001199] 5 7 2.1493651748314284 0.0316054637864269 2.813106796116505 6.104368932038835 1.6405397264547834 0.1100883340733615 1.2852875686886795 0.8042848477475721 1.100790504333474 0.1612592696854457 7.603691798054098e-05 0.0013899505248691 0.0056684159955205 5.522373670119844e-06 9.246798264487089e-06
|
| 4 |
+
Intermediate filament, rod domain [IPR039008] 5 8 2.097975342352379 0.0359073236171256 4.060679611650485 7.546116504854369 0.7869831563787604 0.2926647109331939 1.9153715257926656 0.8924219614624045 1.3691577499316503 0.3120813432784052 0.074492189381682 1.0 1.0 0.0983610682747182 0.0035298468720628
|
interpro_domain/metrics.json
ADDED
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| 1 |
+
{
|
| 2 |
+
"type_of_task": "ranksum",
|
| 3 |
+
"signature_size": 2454,
|
| 4 |
+
"annotations_size": 2199,
|
| 5 |
+
"title": "Average number of proteins per term",
|
| 6 |
+
"value": 2.050022737608004
|
| 7 |
+
}
|
interpro_domain/paths.json
ADDED
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@@ -0,0 +1 @@
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| 1 |
+
{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C339/C339_val_log2fc"}
|
interpro_domain/result.tsv
ADDED
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@@ -0,0 +1,151 @@
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|
| 1 |
+
Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
|
| 2 |
+
P-type ATPase, haloacid dehalogenase domain [IPR044492] 0.843201306655773 2.1673105884219033 0.0302111796747526 1.0 0.4891977146932492 5 P16615,P20020,Q9HD20,P05023 4
|
| 3 |
+
Cytochrome b5-like heme/steroid binding domain [IPR001199] 0.7896828830400402 2.1493651748314284 0.0316054637864269 1.0 0.4891977146932492 7 O15173,O43169,Q8WUJ1,O00264,Q9UMX5 5
|
| 4 |
+
Intermediate filament, rod domain [IPR039008] 0.7133190377454319 2.097975342352379 0.0359073236171256 1.0 0.4891977146932492 8 P02545,P07197,Q16352,P08670,P20700 5
|
| 5 |
+
ERAP1-like C-terminal domain [IPR024571] 0.8633468594791806 1.960518423604341 0.049935226743984 1.0 0.4891977146932492 4 Q9UIQ6,P55786 2
|
| 6 |
+
Peptidase M16, C-terminal [IPR007863] 0.7438777348668353 1.937229494058484 0.0527172964408551 1.0 0.4891977146932492 7 O43847,Q5JRX3,Q10713 3
|
| 7 |
+
Peptidase M16, N-terminal [IPR011765] 0.7438777348668353 1.937229494058484 0.0527172964408551 1.0 0.4891977146932492 7 O43847,Q5JRX3,Q10713 3
|
| 8 |
+
LEM domain [IPR003887] 0.7830169893411056 1.905509466550263 0.0567138780800404 1.0 0.4891977146932492 5 P42167,Q86XL3,P50402 3
|
| 9 |
+
Cation-transporting P-type ATPase, C-terminal [IPR006068] 0.8428571428571416 1.875284477929631 0.0607535976121162 1.0 0.4891977146932492 4 P20020,P05023,P16615 3
|
| 10 |
+
Cation-transporting P-type ATPase, N-terminal [IPR004014] 0.8428571428571416 1.875284477929631 0.0607535976121162 1.0 0.4891977146932492 4 P20020,P05023,P16615 3
|
| 11 |
+
ABC transporter type 1, transmembrane domain [IPR011527] 0.7821744540627442 1.8287234413666595 0.0674410489623615 1.0 0.4891977146932492 6 P08183,P28288,Q03519 3
|
| 12 |
+
Peptidase M1, membrane alanine aminopeptidase [IPR014782] 0.773985877426858 1.792875427257205 0.0729928452954844 1.0 0.4891977146932492 6 Q9UIQ6,P55786,P09960 3
|
| 13 |
+
Aminopeptidase N-like , N-terminal domain [IPR045357] 0.773985877426858 1.792875427257205 0.0729928452954844 1.0 0.4891977146932492 6 Q9UIQ6,P55786,P09960 3
|
| 14 |
+
MCM, AAA-lid domain [IPR041562] 0.7698621903137278 1.774776583449412 0.075934784266697 1.0 0.4891977146932492 6 Q14566 1
|
| 15 |
+
MCM domain [IPR001208] 0.7698621903137278 1.774776583449412 0.075934784266697 1.0 0.4891977146932492 6 Q14566 1
|
| 16 |
+
MCM N-terminal domain [IPR027925] 0.7698621903137278 1.774776583449412 0.075934784266697 1.0 0.4891977146932492 6 Q14566 1
|
| 17 |
+
MCM OB domain [IPR033762] 0.7698621903137278 1.774776583449412 0.075934784266697 1.0 0.4891977146932492 6 Q14566 1
|
| 18 |
+
ABC transporter-like, ATP-binding domain [IPR003439] 0.6322265803532345 1.6694351751606211 0.095031167447805 1.0 0.5334017027948917 9 P08183,P28288,Q03519 3
|
| 19 |
+
Target SNARE coiled-coil homology domain [IPR000727] 0.7869387755102024 1.6396549413410075 0.1010769326031071 1.0 0.5334017027948917 4 O15400,Q86Y82,Q9UNK0 3
|
| 20 |
+
Dynamin, N-terminal [IPR045063] 0.7382275226204509 1.63494305686578 0.1020609852551859 1.0 0.5334017027948917 6 O60313,Q8IWA4 2
|
| 21 |
+
Dynamin-type guanine nucleotide-binding (G) domain [IPR030381] 0.7382275226204509 1.63494305686578 0.1020609852551859 1.0 0.5334017027948917 6 O60313,Q8IWA4 2
|
| 22 |
+
Tubulin/FtsZ, 2-layer sandwich domain [IPR018316] 0.7763305582305653 1.5945134563000507 0.1108210792636814 1.0 0.5353380520652301 4 P07437,P68371 2
|
| 23 |
+
Tubulin/FtsZ, GTPase domain [IPR003008] 0.7763305582305653 1.5945134563000507 0.1108210792636814 1.0 0.5353380520652301 4 P07437,P68371 2
|
| 24 |
+
Band 7 domain [IPR001107] 0.7030228758169944 1.477444358234164 0.1395565630513344 1.0 0.5808777180723087 6 Q9UJZ1,O94905,P35232,Q99623,O75955 5
|
| 25 |
+
Metaxin, glutathione S-transferase domain [IPR033468] 0.8218871343396985 1.42443054048712 0.1543218786918792 1.0 0.6044804288932428 3 Q13505 1
|
| 26 |
+
Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564] 0.8218871343396985 1.42443054048712 0.1543218786918792 1.0 0.6044804288932428 3 Q13505 1
|
| 27 |
+
Polyketide synthase, enoylreductase domain [IPR020843] 0.6848168568568103 1.395329385847898 0.1629165345308529 1.0 0.6063264438374893 6 Q8N4Q0,Q99536,Q8WWV3 3
|
| 28 |
+
NOPS [IPR012975] 0.8090575275397794 1.3722533353536428 0.1699845870514549 1.0 0.6088207583550796 3 Q8WXF1,Q15233 2
|
| 29 |
+
TRAM/LAG1/CLN8 homology domain [IPR006634] 0.98858075040783 1.358225148007525 0.174392253169821 1.0 0.6088207583550796 2 Q96G23 1
|
| 30 |
+
GOLD domain [IPR009038] 0.7196328476369719 1.3515302009708796 0.1765256522496718 1.0 0.6122711503107704 4 Q9Y3B3,P49755 2
|
| 31 |
+
Lamin tail domain [IPR001322] 0.796817625459003 1.322462998371821 0.186014022809301 1.0 0.6273693806098971 3 P02545,P20700 2
|
| 32 |
+
Reticulon [IPR003388] 0.964926590538334 1.2697432208362849 0.2041761117740406 1.0 0.638667524596181 2 O95197 1
|
| 33 |
+
Phospholipid/glycerol acyltransferase [IPR002123] 0.7757069926057873 1.2366426616525577 0.2162197743063898 1.0 0.658541944182481 3 Q8NF37 1
|
| 34 |
+
Alcohol dehydrogenase, N-terminal [IPR013154] 0.62380703900691 1.1846013113842582 0.2361751182969915 1.0 0.6883422849439754 5 Q8WWV3 1
|
| 35 |
+
Sterile alpha motif domain [IPR001660] 0.6649125799866884 1.115948932092509 0.2644439947576664 1.0 0.707837187226279 4 Q8IXK0,Q15375 2
|
| 36 |
+
Intermediate filament head, DNA-binding domain [IPR006821] 0.6641956995286304 1.1128690342038192 0.2657646810177714 1.0 0.707837187226279 4 Q16352,P08670 2
|
| 37 |
+
EF-hand domain [IPR002048] 0.4456086053790567 1.0836152818169236 0.2785354122475576 1.0 0.7214362444433207 37 Q96D71,Q14257,P80303,Q9Y680,Q8NF37,Q9NWM8,Q9UJS0,Q02818,O95202 9
|
| 38 |
+
Major facilitator superfamily domain [IPR020846] 0.9131321370309932 1.077692995148636 0.2811707855558538 1.0 0.7245012554591178 2 Q6NT16 1
|
| 39 |
+
Zinc finger, CHHC-type [IPR012996] 0.7356181150550793 1.0744022012545504 0.2826424563391736 1.0 0.7245012554591178 3 P31943,P55795 2
|
| 40 |
+
Fzo/mitofusin HR2 domain [IPR006884] 0.8894779771615001 0.9912675853548888 0.3215549365184169 1.0 0.7778870246468634 2 Q8IWA4 1
|
| 41 |
+
SCP2 sterol-binding domain [IPR003033] 0.7137106038904921 0.98655725373175 0.323859734557669 1.0 0.7790824564177824 3 P51659 1
|
| 42 |
+
Dynamin, GTPase domain [IPR001401] 0.706650346797234 0.958430720356892 0.3378456105122891 1.0 0.7800971808725775 3 O60313,P50570 2
|
| 43 |
+
MD-2-related lipid-recognition domain [IPR003172] 0.870717781402931 0.9235547005329868 0.3557182081736991 1.0 0.7895998855726628 2 P17900 1
|
| 44 |
+
GNAT domain [IPR000182] 0.6866585067319462 0.8794080639425703 0.3791800613709839 1.0 0.8180375872178486 3 Q9GZZ1,Q86UY6 2
|
| 45 |
+
Syntaxin, N-terminal domain [IPR006011] 0.8527732463295283 0.8596364396733713 0.3899894815523135 1.0 0.83015592088726 2 O15400 1
|
| 46 |
+
Proteasome activator PA28, C-terminal domain [IPR003186] 0.6796562825160228 0.8519830244934763 0.3942235139415053 1.0 0.8319553811491077 3 Q9UL46 1
|
| 47 |
+
Proteasome activator PA28, N-terminal domain [IPR003185] 0.6796562825160228 0.8519830244934763 0.3942235139415053 1.0 0.8319553811491077 3 Q9UL46 1
|
| 48 |
+
FAD-binding domain, PCMH-type [IPR016166] 0.8478792822185913 0.8423693230196333 0.3995812587580256 1.0 0.83287126825488 2 O00116 1
|
| 49 |
+
FAD linked oxidase, N-terminal [IPR006094] 0.8478792822185913 0.8423693230196333 0.3995812587580256 1.0 0.83287126825488 2 O00116 1
|
| 50 |
+
FAD/NAD(P)-binding domain [IPR023753] 0.5984412050139518 0.8334595762987647 0.4045855868891514 1.0 0.834600099033062 4 O95831 1
|
| 51 |
+
Plasma membrane calcium transporting P-type ATPase, C-terminal [IPR022141] 0.8421696574225135 0.8223220315493903 0.4108936409572794 1.0 0.8349715197825683 2 P20020 1
|
| 52 |
+
Tim44-like domain [IPR007379] 0.838499184339315 0.809492472170085 0.4182319311218827 1.0 0.8410905414745538 2 O43615 1
|
| 53 |
+
Myosin tail [IPR002928] 0.6638106895144833 0.7905010898799325 0.4292351859766639 1.0 0.8488203003261546 3 Q7Z406,P35579 2
|
| 54 |
+
4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896] 0.6626951111237307 0.7862058163712207 0.4317469191119254 1.0 0.8498097007934773 3 Q16134 1
|
| 55 |
+
Oxidoreductase, N-terminal domain [IPR041694] 0.8005709624796 0.6799716896586676 0.4965223867862454 1.0 0.8959930258311679 2 Q8N8N7 1
|
| 56 |
+
SET domain [IPR001214] 0.6312104601360449 0.6671397617989014 0.5046828641729677 1.0 0.9030086398017544 3 Q03164 1
|
| 57 |
+
ATPase family AAA domain-containing protein 3, N-terminal [IPR021911] 0.7936378466557905 0.6569819681726883 0.5111925109349829 1.0 0.9044031422800236 2 Q9NVI7 1
|
| 58 |
+
CARG-binding factor, N-terminal [IPR012956] 0.7928221859706367 0.6542929378126939 0.5129230949082635 1.0 0.9044031422800236 2 Q99729 1
|
| 59 |
+
Ribosomal protein L18e/L15P [IPR021131] 0.6269919215759696 0.6515458077364578 0.514694217133767 1.0 0.9054500667817228 3 Q07020 1
|
| 60 |
+
RNA-binding S4 domain [IPR002942] 0.6262749898000829 0.6489051326880945 0.5163996969413223 1.0 0.905464036543004 3 P46781,Q9NV31 2
|
| 61 |
+
L27 domain, C-terminal [IPR014775] 0.7838499184339313 0.6249400371930515 0.5320104137404442 1.0 0.9168423979743237 2 Q14168 1
|
| 62 |
+
L27 domain [IPR004172] 0.7838499184339313 0.6249400371930515 0.5320104137404442 1.0 0.9168423979743237 2 Q14168 1
|
| 63 |
+
Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375] 0.5404931668745405 0.5981361904011868 0.5497490639968408 1.0 0.9331824981230452 4 P13798 1
|
| 64 |
+
v-SNARE, coiled-coil homology domain [IPR042855] 0.60408980034934 0.5686719166417334 0.5695788095723491 1.0 0.9331824981230452 3 P51809 1
|
| 65 |
+
Longin domain [IPR010908] 0.60408980034934 0.5686719166417334 0.5695788095723491 1.0 0.9331824981230452 3 P51809 1
|
| 66 |
+
Chromo domain [IPR023780] 0.5293877551020363 0.5550762999201042 0.5788424727432513 1.0 0.9331824981230452 4 Q14839,P45973,P83916 3
|
| 67 |
+
Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337] 0.7540783034257772 0.5308077747063125 0.5955519918863132 1.0 0.9406863039459056 2 O60506 1
|
| 68 |
+
Zinc finger, CXXC-type [IPR002857] 0.5843699590585145 0.5000848078894247 0.617015362883516 1.0 0.9533591164654602 3 Q03164 1
|
| 69 |
+
Extended PHD (ePHD) domain [IPR034732] 0.7402120717781271 0.4888886381773106 0.6249205399648781 1.0 0.9562980287980284 2 Q03164 1
|
| 70 |
+
Immunoglobulin subtype 2 [IPR003598] 0.4651428078942868 0.4796495260761955 0.6314766237510949 1.0 0.9596524503307932 5 P35613 1
|
| 71 |
+
Immunoglobulin-like domain [IPR007110] 0.4067587688330928 0.4631210210509266 0.6432776231573765 1.0 0.961636637201272 9 P35613,P10321 2
|
| 72 |
+
3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108] 0.7243066884176215 0.4425007938027191 0.6581268560062175 1.0 0.9666691118072224 2 P40939 1
|
| 73 |
+
3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176] 0.7243066884176215 0.4425007938027191 0.6581268560062175 1.0 0.9666691118072224 2 P40939 1
|
| 74 |
+
Peptidase M3A/M3B catalytic domain [IPR001567] 0.560077739481248 0.4198067065349989 0.6746266652028003 1.0 0.9666691118072224 3 Q99797 1
|
| 75 |
+
CYRIA/CYRIB, Rac1 binding domain [IPR009828] 0.7079934747145062 0.3969706694929228 0.6913890896745198 1.0 0.9666691118072224 2 Q9NUQ9 1
|
| 76 |
+
Sorting nexin Vps5-like, C-terminal [IPR015404] 0.5528355773153842 0.3968903322892413 0.6914483336774266 1.0 0.9666691118072224 3 Q9UNH7,O60749 2
|
| 77 |
+
F-box domain [IPR001810] 0.551468522826789 0.3926208711692583 0.6945995220143648 1.0 0.9666691118072224 3 Q14241 1
|
| 78 |
+
Dynamin stalk domain [IPR000375] 0.7063621533442092 0.3925383415234369 0.6946604874360323 1.0 0.9666691118072224 2 P50570 1
|
| 79 |
+
Dynamin GTPase effector [IPR003130] 0.7063621533442092 0.3925383415234369 0.6946604874360323 1.0 0.9666691118072224 2 P50570 1
|
| 80 |
+
GTPase effector domain [IPR020850] 0.7063621533442092 0.3925383415234369 0.6946604874360323 1.0 0.9666691118072224 2 P50570 1
|
| 81 |
+
Rhodanese-like domain [IPR001763] 0.4848979591836682 0.3922366200061659 0.6948833887511316 1.0 0.9666691118072224 4 P25325,P40818,Q8NCN5 3
|
| 82 |
+
Beta-hexosaminidase, eukaryotic type, N-terminal [IPR029019] 0.705138662316477 0.3892289382005501 0.6971067983954 1.0 0.9666691118072224 2 P07686 1
|
| 83 |
+
Glycoside hydrolase family 20, catalytic domain [IPR015883] 0.705138662316477 0.3892289382005501 0.6971067983954 1.0 0.9666691118072224 2 P07686 1
|
| 84 |
+
Brix domain [IPR007109] 0.5499796001632066 0.3879915810483088 0.6980222638976168 1.0 0.9666691118072224 3 Q8TDN6,Q9H7B2 2
|
| 85 |
+
CBS domain [IPR000644] 0.5486502953565016 0.3838770312712589 0.7010695909211366 1.0 0.9666691118072224 3 Q6P4Q7 1
|
| 86 |
+
Class II aldolase/adducin N-terminal [IPR001303] 0.7030995106035898 0.3837417499299506 0.7011698653225453 1.0 0.9666691118072224 2 P35611 1
|
| 87 |
+
JAB1/MPN/MOV34 metalloenzyme domain [IPR000555] 0.4186411513445626 0.3698834146248022 0.7114693596434987 1.0 0.9666691118072224 7 Q92905,Q7L5N1 2
|
| 88 |
+
Alcohol dehydrogenase-like, C-terminal [IPR013149] 0.4467075170418897 0.3486254660546963 0.7273705066878593 1.0 0.9666691118072224 6 Q8N4Q0 1
|
| 89 |
+
Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547] 0.6843393148450271 0.3349849764308995 0.7376364192184921 1.0 0.9666691118072224 2 O15460 1
|
| 90 |
+
p21 activated kinase binding domain [IPR033923] 0.6818923327895616 0.328862336428894 0.7422597434502158 1.0 0.9666691118072224 2 O96013 1
|
| 91 |
+
CRIB domain [IPR000095] 0.6818923327895616 0.328862336428894 0.7422597434502158 1.0 0.9666691118072224 2 O96013 1
|
| 92 |
+
Chromo shadow domain [IPR008251] 0.5291717666258624 0.3256734742031772 0.7446714155209861 1.0 0.9666691118072224 3 P45973,P83916 2
|
| 93 |
+
Chromo domain subgroup [IPR017984] 0.5291717666258624 0.3256734742031772 0.7446714155209861 1.0 0.9666691118072224 3 P45973,P83916 2
|
| 94 |
+
Immunoglobulin subtype [IPR003599] 0.4373355481860238 0.3132591185613444 0.754083806777786 1.0 0.9666691118072224 6 P35613 1
|
| 95 |
+
Aldehyde dehydrogenase domain [IPR015590] 0.3759398013962035 0.3114480480165813 0.755460031821233 1.0 0.9666691118072224 9 P51648 1
|
| 96 |
+
Ribosomal protein S4/S9, N-terminal [IPR001912] 0.6680261011419278 0.2952468185032655 0.7678053391777122 1.0 0.9666691118072224 2 P46781 1
|
| 97 |
+
MIRO domain [IPR020860] 0.6610929853181098 0.2791454157058501 0.7801332310825531 1.0 0.9666691118072224 2 Q8IXI1 1
|
| 98 |
+
EF hand associated, type-2 [IPR013567] 0.6610929853181098 0.2791454157058501 0.7801332310825531 1.0 0.9666691118072224 2 Q8IXI1 1
|
| 99 |
+
EF hand associated, type-1 [IPR013566] 0.6610929853181098 0.2791454157058501 0.7801332310825531 1.0 0.9666691118072224 2 Q8IXI1 1
|
| 100 |
+
OBG-type guanine nucleotide-binding (G) domain [IPR031167] 0.4054716210698284 0.2564163575183107 0.7976293585036931 1.0 0.9666691118072224 5 P55039,Q9NTK5,Q9BZE4,A4D1E9 4
|
| 101 |
+
GUCT [IPR012562] 0.6492659053833507 0.2528011838861414 0.8004218528029803 1.0 0.9666691118072224 2 Q9BQ39 1
|
| 102 |
+
Legume-like lectin [IPR005052] 0.6455954323001674 0.2449189323525144 0.8065192021614709 1.0 0.9666691118072224 2 P49257 1
|
| 103 |
+
Ribosomal protein L7, eukaryotic/archaeal [IPR035808] 0.6427406199021238 0.2388858022831277 0.8111941350194818 1.0 0.9666691118072224 2 Q6DKI1 1
|
| 104 |
+
Ribosomal protein L30, ferredoxin-like fold domain [IPR016082] 0.6427406199021238 0.2388858022831277 0.8111941350194818 1.0 0.9666691118072224 2 Q6DKI1 1
|
| 105 |
+
Ribosomal protein L30, N-terminal [IPR012988] 0.6427406199021238 0.2388858022831277 0.8111941350194818 1.0 0.9666691118072224 2 Q6DKI1 1
|
| 106 |
+
FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179] 0.3527457753542603 0.2054275800460202 0.8372380739825718 1.0 0.9666691118072224 9 Q9NWM8 1
|
| 107 |
+
ATP:guanido phosphotransferase, catalytic domain [IPR022414] 0.6252039151712943 0.2037260666897278 0.8385675710927558 1.0 0.9666691118072224 2 P12277 1
|
| 108 |
+
ATP:guanido phosphotransferase, N-terminal [IPR022413] 0.6252039151712943 0.2037260666897278 0.8385675710927558 1.0 0.9666691118072224 2 P12277 1
|
| 109 |
+
Transcription factor IIS, N-terminal [IPR017923] 0.4773343159858684 0.1922974727200731 0.8475091979350364 1.0 0.9666691118072224 3 Q14241 1
|
| 110 |
+
Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type [IPR003617] 0.4773343159858684 0.1922974727200731 0.8475091979350364 1.0 0.9666691118072224 3 Q14241 1
|
| 111 |
+
Heat shock chaperonin-binding [IPR006636] 0.4736842105263245 0.1842059812078512 0.8538518674481064 1.0 0.9666691118072224 3 P54727,Q9NRR5 2
|
| 112 |
+
Fxr1, tudor domain [IPR041560] 0.4712362301101648 0.1788805250841388 0.8580315148660129 1.0 0.9666691118072224 3 P51116,Q06787 2
|
| 113 |
+
Synaptic functional regulator FMRP, KH0 domain [IPR040472] 0.4712362301101648 0.1788805250841388 0.8580315148660129 1.0 0.9666691118072224 3 P51116,Q06787 2
|
| 114 |
+
Agenet-like domain [IPR008395] 0.4712362301101648 0.1788805250841388 0.8580315148660129 1.0 0.9666691118072224 3 P51116,Q06787 2
|
| 115 |
+
Fragile X-related 1 protein, C-terminal core [IPR022034] 0.4712362301101648 0.1788805250841388 0.8580315148660129 1.0 0.9666691118072224 3 P51116,Q06787 2
|
| 116 |
+
FAD dependent oxidoreductase [IPR006076] 0.4659322725418177 0.16762274095882 0.8668800796325551 1.0 0.9667404554474672 3 P43304,Q8NCN5 2
|
| 117 |
+
HR1 rho-binding domain [IPR011072] 0.5950244698205615 0.1510377871887165 0.8799459079397705 1.0 0.9702039377941412 2 Q16513 1
|
| 118 |
+
Serine hydroxymethyltransferase-like domain [IPR039429] 0.5848287112561251 0.1354936109374344 0.8922216154101594 1.0 0.9702039377941412 2 P34896 1
|
| 119 |
+
Guanylate kinase-like domain [IPR008144] 0.3959766307470262 0.1346253037545459 0.8929081342288834 1.0 0.9702039377941412 4 Q14168 1
|
| 120 |
+
Guanylate kinase/L-type calcium channel beta subunit [IPR008145] 0.3959766307470262 0.1346253037545459 0.8929081342288834 1.0 0.9702039377941412 4 Q14168 1
|
| 121 |
+
Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862] 0.4467564259485902 0.1301663722871336 0.8964347992124928 1.0 0.9705859790587256 3 O15460,P13674 2
|
| 122 |
+
Ribosomal protein S7 domain [IPR023798] 0.576672104404576 0.1238731475257062 0.901415714336975 1.0 0.9745192507788084 2 Q9Y2R9 1
|
| 123 |
+
Septin-type guanine nucleotide-binding (G) domain [IPR030379] 0.431660546715627 0.1042864524255502 0.916942028687175 1.0 0.977013197038262 3 Q16181,Q15019 2
|
| 124 |
+
AMP-dependent synthetase/ligase [IPR000873] 0.3511637403021673 0.0975097074351722 0.9223216255500576 1.0 0.9814048935152024 5 O60488,O95573,Q6P1M0,P33121 4
|
| 125 |
+
Sorting nexin, N-terminal [IPR005329] 0.5526101141925033 0.093727037882632 0.925325991691829 1.0 0.982516588957186 2 O60749 1
|
| 126 |
+
Chaperone DnaJ, C-terminal [IPR002939] 0.3722448979591778 0.0857722343278651 0.931647478913174 1.0 0.9868462457273935 4 P25685,O60884,P31689 3
|
| 127 |
+
Zinc finger C2H2 AKAP95-type [IPR034736] 0.5379282218597143 0.0782580134934232 0.9376228153682926 1.0 0.9917424583909936 2 Q5BKZ1 1
|
| 128 |
+
Ribosomal protein S5, C-terminal [IPR005324] 0.5326264274062078 0.0731919893354346 0.9416533408761498 1.0 0.9939338487742778 2 P82675 1
|
| 129 |
+
Ribosomal protein S5, N-terminal [IPR013810] 0.5326264274062078 0.0731919893354346 0.9416533408761498 1.0 0.9939338487742778 2 P82675 1
|
| 130 |
+
Uncharacterised domain CHP00451 [IPR004521] 0.532218597063623 0.0728134235885963 0.9419545888338312 1.0 0.9939338487742778 2 Q9ULC4 1
|
| 131 |
+
Far upstream element-binding protein, C-terminal [IPR015096] 0.5191680261011475 0.0615156273157976 0.9509485691776562 1.0 0.9995869520180048 2 Q96AE4 1
|
| 132 |
+
Domain of unknown function DUF4749 [IPR031847] 0.5183523654159966 0.0608608896211146 0.951469997238005 1.0 0.999657202067068 2 O00151 1
|
| 133 |
+
Translation initiation factor IF- 2, domain 3 [IPR023115] 0.5089722675367081 0.0537485217194975 0.9571355239034556 1.0 1.0 2 P46199 1
|
| 134 |
+
Ribosomal protein S10 domain [IPR027486] 0.5061174551386705 0.0517324915981617 0.9587418473421307 1.0 1.0 2 Q96GC5 1
|
| 135 |
+
26S proteasome regulatory subunit Rpn7, N-terminal [IPR045135] 0.5044861337683549 0.050610758113319 0.9596356900784522 1.0 1.0 2 Q13098 1
|
| 136 |
+
Ribosomal protein L2, C-terminal [IPR022669] 0.5036704730831996 0.0500580596622557 0.9600761213522768 1.0 1.0 2 P62917 1
|
| 137 |
+
Ribosomal Proteins L2, RNA binding domain [IPR022666] 0.5036704730831996 0.0500580596622557 0.9600761213522768 1.0 1.0 2 P62917 1
|
| 138 |
+
Ribosomal L28e/Mak16 [IPR029004] 0.4836867862969021 0.038135337388979 0.9695797766301832 1.0 1.0 2 P46779 1
|
| 139 |
+
Major sperm protein (MSP) domain [IPR000535] 0.4812398042414492 0.0368775262932545 0.970582658976112 1.0 1.0 2 O95292 1
|
| 140 |
+
EB1, C-terminal [IPR004953] 0.4808319738988606 0.0366719320409254 0.9707465885704508 1.0 1.0 2 Q15691 1
|
| 141 |
+
Hotdog acyl-CoA thioesterase (ACOT)-type domain [IPR033120] 0.4771615008156746 0.0348726194430889 0.9721813138479722 1.0 1.0 2 Q9Y305 1
|
| 142 |
+
Fragile X-related 1 protein, C-terminal region 1 [IPR032172] 0.4710440456770082 0.0320721377856775 0.9744145228015916 1.0 1.0 2 P51116 1
|
| 143 |
+
Heat shock protein DnaJ, cysteine-rich domain [IPR001305] 0.372093023255812 0.0320141317635064 0.9744607811568402 1.0 1.0 3 O60884,P31689 2
|
| 144 |
+
Damage-control phosphatase ARMT1-like, metal-binding domain [IPR002791] 0.4649265905383499 0.0295083310845659 0.9764591745914768 1.0 1.0 2 Q9H993 1
|
| 145 |
+
Disulphide isomerase [IPR005788] 0.3184973458554551 0.0276851369346623 0.977913278168682 1.0 1.0 5 P30101,Q8NBS9,P07237,Q15084 4
|
| 146 |
+
MPN domain [IPR037518] 0.3009982789315063 0.0248404566894971 0.9801822212328596 1.0 1.0 8 Q92905,Q7L5N1 2
|
| 147 |
+
AMP-binding enzyme, C-terminal domain [IPR025110] 0.3508771929824536 0.0165198252543893 0.986819685979867 1.0 1.0 3 Q6P1M0,P33121 2
|
| 148 |
+
DNA2/NAM7 helicase-like, C-terminal [IPR041679] 0.4184339314845096 0.0164133505669758 0.9869046289721666 1.0 1.0 2 Q9HCE1 1
|
| 149 |
+
Arginyl-tRNA synthetase, catalytic core domain [IPR035684] 0.3951876019575859 0.013019092092733 0.989612560863911 1.0 1.0 2 Q5T160 1
|
| 150 |
+
DALR anticodon binding [IPR008909] 0.3951876019575859 0.013019092092733 0.989612560863911 1.0 1.0 2 Q5T160 1
|
| 151 |
+
Arf GTPase activating protein [IPR001164] 0.3833605220228471 0.011834510112881 0.9905576475058852 1.0 1.0 2 Q8N6T3 1
|
interpro_domain/selections.json
ADDED
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interpro_family/advanced/idx2term.json
ADDED
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@@ -0,0 +1 @@
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| 1 |
+
{"0": "Mitochondrial carrier protein [IPR002067]"}
|
interpro_family/advanced/plot_0.png
ADDED
|
Git LFS Details
|
interpro_family/basic/idx2term.json
ADDED
|
@@ -0,0 +1 @@
|
|
|
|
|
|
|
| 1 |
+
{"0": "Mitochondrial carrier protein [IPR002067]", "1": "Small GTPase Rho [IPR003578]"}
|
interpro_family/basic/plot_0.png
ADDED
|
Git LFS Details
|
interpro_family/basic/plot_1.png
ADDED
|
Git LFS Details
|
interpro_family/consensus.joblib
ADDED
|
@@ -0,0 +1,3 @@
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|
| 1 |
+
version https://git-lfs.github.com/spec/v1
|
| 2 |
+
oid sha256:d5208a11d234635208f89fbb96f820c5803f7771273c1fa78c7b9440ccb6d8dd
|
| 3 |
+
size 181437
|
interpro_family/df_merge.tsv
ADDED
|
@@ -0,0 +1,3 @@
|
|
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|
| 1 |
+
term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
|
| 2 |
+
Mitochondrial carrier protein [IPR002067] 7 8 2.65356295144332 0.0079646912513007 5.686893203883495 11.07766990291262 0.8032246115450145 0.31892620527414 3.2338505495684404 1.5403272908315857 1.3918146051602212 0.3274613788058813 0.0629177238061625 1.0 1.0 0.0834574734746242 2.2237850571674797e-06
|
| 3 |
+
P-type ATPase [IPR001757] 4 5 2.1673105884219037 0.0302111796747526 2.941747572815534 6.145631067961165 0.9567723497044874 0.2732808833570771 1.8358630293390923 1.459204245106796 1.2102525517005158 0.2943240638910574 0.074492189381682 1.0 0.191600110602388 0.0153906222854723 0.0035298468720628
|
interpro_family/metrics.json
ADDED
|
@@ -0,0 +1,7 @@
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|
|
|
|
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|
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|
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|
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|
|
|
|
|
|
|
| 1 |
+
{
|
| 2 |
+
"type_of_task": "ranksum",
|
| 3 |
+
"signature_size": 2454,
|
| 4 |
+
"annotations_size": 1958,
|
| 5 |
+
"title": "Average number of proteins per term",
|
| 6 |
+
"value": 1.2584269662921348
|
| 7 |
+
}
|
interpro_family/paths.json
ADDED
|
@@ -0,0 +1 @@
|
|
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|
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|
| 1 |
+
{"results_path": "results/proteins/hek293t_core/interpro_family/fragment/C339/C339_val_log2fc"}
|