diff --git a/interpro_active_site/advanced/idx2term.json b/interpro_active_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_active_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_active_site/basic/idx2term.json b/interpro_active_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_active_site/basic/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_active_site/consensus.joblib b/interpro_active_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..92b9f1c0c3e01bd7288808b596591b3ec759b8af --- /dev/null +++ b/interpro_active_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5e48ff1763ddc6af8398ca69553d4d9417829634ad8b380695511d381eca8568 +size 81650 diff --git a/interpro_active_site/df_merge.tsv b/interpro_active_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_active_site/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_active_site/metrics.json b/interpro_active_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..d5a304de29ba288b54b11ab7f0c71667ac999395 --- /dev/null +++ b/interpro_active_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3329, + "annotations_size": 57, + "title": "Average number of proteins per term", + "value": 2.8421052631578947 +} \ No newline at end of file diff --git a/interpro_active_site/paths.json b/interpro_active_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..0512704a4cf85d16cb61ba61e6914842348ea22f --- /dev/null +++ b/interpro_active_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C342/C342_val_log2fc"} \ No newline at end of file diff --git a/interpro_active_site/result.tsv b/interpro_active_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..f4e6950f98ef64029d291c9d8746659dab5daa97 --- /dev/null +++ b/interpro_active_site/result.tsv @@ -0,0 +1,8 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Serine carboxypeptidase, serine active site [IPR018202] 0.9738424533974744 1.661986942064216 0.0965153926992665 0.9969275614996655 0.2500626083571907 3 Q9H3G5,Q9HB40 2 +Ribonucleotide reductase small subunit, acitve site [IPR030475] 0.780583107905001 1.0561432992818989 0.2909027508669424 0.9999999969080632 0.5527152266471905 2 Q7LG56 1 +Cysteine peptidase, asparagine active site [IPR025661] 0.757439134355258 0.9641998448292228 0.334945742169364 0.9999999999200436 0.5785426455652651 2 P07858 1 +Cysteine peptidase, histidine active site [IPR025660] 0.757439134355258 0.9641998448292228 0.334945742169364 0.9999999999200436 0.5785426455652651 2 P07858 1 +Cysteine peptidase, cysteine active site [IPR000169] 0.4081525884569559 0.2120351138145455 0.8320796402253674 1.0 0.9065163332169984 5 P17655,P07858 2 +Glycosyl hydrolases family 31, active site [IPR030458] 0.4283137962127976 0.0902212948187578 0.9281113625161486 1.0 0.9446847797039368 2 P10253 1 +Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999] 0.4107035478051607 0.0576987224443023 0.9539886113444018 1.0 0.9539886113444018 3 Q16881,P09622 2 diff --git a/interpro_active_site/selections.json b/interpro_active_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..b77feb952ac1146193b5fc74e0ef22f839a56571 --- /dev/null +++ b/interpro_active_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]"], "available_proteins": ["AAK1", "ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT1", "APEH", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "BLMH", "BUB1", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CASP2", "CASP3", "CDC42BPB", "CDK1", "CDK11B", "CDK4", "CDK5", "CDK6", "CHEK1", "CHEK2", "CHUK", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSB", "CTSC", "DLD", "DNMT1", "DUSP3", "EGFR", "EIF2AK2", "EIF2AK4", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSK3A", "GSK3B", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "IGF1R", "IKBKB", "LDHA", "LDHB", "LONP1", "MAP2K1", "MAP2K3", "MAPK1", "MAPK3", "MARK1", "MARK2", "MDH1", "MDH2", "MTMR2", "NEK9", "NME1", "NME2", "NME3", "OXCT1", "PAK1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKN1", "PKN2", "PLK1", "PREP", "PRKAA1", "PRKAA2", "PRKACA", "PRKCD", "PRPF4B", "PTK7", "PTPN1", "PTPN11", "PTPN23", "PTPN9", "PTPRF", "RIPK1", "RNASET2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "RRM2B", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TPI1", "TPP2", "TRIO", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UBE2T", "UMPS", "VRK1", "VRK2", "WNK1", "WNK2"], "leading_proteins": ["CAPN2", "CPVL", "CTSB", "DLD", "GAA", "RRM2B", "SCPEP1", "TXNRD1"]} \ No newline at end of file diff --git a/interpro_binding_site/advanced/idx2term.json b/interpro_binding_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_binding_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_binding_site/basic/idx2term.json b/interpro_binding_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..1f2df466d020a9613ebb803cec2bf89e8e4d80ca --- /dev/null +++ b/interpro_binding_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "EF-Hand 1, calcium-binding site [IPR018247]"} \ No newline at end of file diff --git a/interpro_binding_site/basic/plot_0.png b/interpro_binding_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..039656a68df64d5f4b7d4666c11dbfff19a727c4 --- /dev/null +++ b/interpro_binding_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3876ed4d249854875598cc20b115d3fa8321b2a620ead16b24fc10e1c8cf5d3b +size 140258 diff --git a/interpro_binding_site/consensus.joblib b/interpro_binding_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..bdd398d113c81a25d82d5e313b6457fc93381f5f --- /dev/null +++ b/interpro_binding_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2b75b99602228e571ad59aec32ff0c26f188f518a31c30b411205fb6faf3747c +size 76120 diff --git a/interpro_binding_site/df_merge.tsv b/interpro_binding_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_binding_site/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_binding_site/metrics.json b/interpro_binding_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..5cd0c06fa254e1747124df562658538b8733ecf9 --- /dev/null +++ b/interpro_binding_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3329, + "annotations_size": 31, + "title": "Average number of proteins per term", + "value": 4.903225806451613 +} \ No newline at end of file diff --git a/interpro_binding_site/paths.json b/interpro_binding_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..2510213b1ff72b3e982f5a8c724dbbc1a514b6ab --- /dev/null +++ b/interpro_binding_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C342/C342_val_log2fc"} \ No newline at end of file diff --git a/interpro_binding_site/result.tsv b/interpro_binding_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c17f541f840480df4bd032d8ae3692cb02696701 --- /dev/null +++ b/interpro_binding_site/result.tsv @@ -0,0 +1,5 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +EF-Hand 1, calcium-binding site [IPR018247] 0.4667962976562564 1.638589054372743 0.1012988734366666 0.9635184006861652 0.3284429590733821 40 Q9Y680,Q02818,P80303,Q96AY3,Q14257 5 +Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798] 0.91794409377818 1.6166708858695076 0.1059493416365748 0.96893824806271 0.3284429590733821 2 P34896 1 +Hexokinase, binding site [IPR019807] 0.7171626089570039 0.8082651094792781 0.4189379833195228 0.9999999509208424 0.6684387730313582 2 P52789 1 +Peptidase M16, zinc-binding site [IPR001431] 0.3038507821901392 0.0208099389752326 0.9833972693009996 1.0 1.0 5 Q10713,P14735,P22695,O75439 4 diff --git a/interpro_binding_site/selections.json b/interpro_binding_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..123d4bea23417983efc9daff1a5a679cb160faf1 --- /dev/null +++ b/interpro_binding_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT1", "APEX1", "APOBEC3C", "BPNT1", "BUB1", "CALM3", "CALU", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CAPNS1", "CDC42BPB", "CDK1", "CDK4", "CDK5", "CDK6", "CETN2", "CHEK1", "CHUK", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DCTD", "DLAT", "DLST", "DST", "EGFR", "EHD1", "EHD4", "EIF2AK2", "EIF2AK4", "EPS15", "EPS15L1", "FKBP10", "FKBP14", "FKBP7", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "IGF1R", "ILKAP", "IMPA1", "IQGAP1", "IQGAP2", "ITSN2", "LETM1", "MACF1", "MAP2K1", "MAP2K3", "MAPK1", "MAPK14", "MAPK3", "MARK1", "MARK2", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXCT1", "OXSR1", "PA2G4", "PAK1", "PAK2", "PAK4", "PC", "PCCA", "PDCD6", "PEF1", "PGD", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1G", "PRKAA1", "PRKAA2", "PRKACA", "PRKCD", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "STK26", "STK4", "TBK1", "TKT", "TTK", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "UQCRC2", "VRK1"], "leading_proteins": ["FKBP10", "FKBP7", "HK2", "IDE", "NUCB1", "NUCB2", "PMPCA", "PMPCB", "RCN2", "SHMT1", "UQCRC2"]} \ No newline at end of file diff --git a/interpro_conserved_site/advanced/idx2term.json b/interpro_conserved_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_conserved_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_conserved_site/basic/idx2term.json b/interpro_conserved_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..51dfa88214da95d148dbffb95702a7d49fe6a369 --- /dev/null +++ b/interpro_conserved_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "14-3-3 protein, conserved site [IPR023409]"} \ No newline at end of file diff --git a/interpro_conserved_site/basic/plot_0.png b/interpro_conserved_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..2d2ff6f7f33fb9de96ed27597c98a8d8e4e7ed34 --- /dev/null +++ b/interpro_conserved_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1770636a10bea24afe4c277a0e9c1e846ceceddf8415e62046dfaa3b403dc557 +size 138796 diff --git a/interpro_conserved_site/consensus.joblib b/interpro_conserved_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..429998c95afbcc1cb0960398156897060c6c00eb --- /dev/null +++ b/interpro_conserved_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d4e3b0f375735683e16d2bb461897d016d22b64c41ac959a34107352175de54b +size 95599 diff --git a/interpro_conserved_site/df_merge.tsv b/interpro_conserved_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c0e7f2dc5e4d25fb8495842c58c2d7caedcf4973 --- /dev/null +++ b/interpro_conserved_site/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Proteasome beta-type subunit, conserved site [IPR016050] 4 8 2.559950887729327 0.0104686956440109 3.7135922330097086 7.970873786407767 1.4913184573846054 0.1902243906475925 1.515457478026574 0.1681602725795027 1.0170822776023185 0.2455850375425174 0.002691599026727 1.0 0.0039921150854813 1.8654270901726772e-06 5.5966724052351854e-05 diff --git a/interpro_conserved_site/metrics.json b/interpro_conserved_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..4b41cc17bb96db591f7d5597928f18942ecb985e --- /dev/null +++ b/interpro_conserved_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3329, + "annotations_size": 275, + "title": "Average number of proteins per term", + "value": 2.7854545454545456 +} \ No newline at end of file diff --git a/interpro_conserved_site/paths.json b/interpro_conserved_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..85e7146be515ad6327b1d57e5121d7c4cec8133c --- /dev/null +++ b/interpro_conserved_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C342/C342_val_log2fc"} \ No newline at end of file diff --git a/interpro_conserved_site/result.tsv b/interpro_conserved_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..587077abc5fef6f356cd719916be1fe2a067b2c0 --- /dev/null +++ b/interpro_conserved_site/result.tsv @@ -0,0 +1,33 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Proteasome beta-type subunit, conserved site [IPR016050] 0.8816010698664067 2.559950887729327 0.0104686956440109 0.9446493248781594 0.1199538042542925 8 P49721,P28070,P28074,P28072 4 +Haem oxygenase conserved site [IPR018207] 0.9843703035767944 1.8880400209766384 0.0590205778978827 0.9999999457331412 0.2687565211881426 2 P30519 1 +Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818] 0.8026898677752794 1.7198268020639045 0.0854639291467145 0.999999999978609 0.331022260779528 5 P48735 1 +Sterol reductase, conserved site [IPR018083] 0.9296663660955744 1.664737341611549 0.0959651695802898 0.9999999999991068 0.3566273193862124 2 Q14739 1 +Syntaxin/epimorphin, conserved site [IPR006012] 0.7145006016847399 1.359654208135973 0.1739393753166065 1.0 0.4836443998871719 5 Q86Y82,O43752,Q9P2W9,O15400 4 +C-type lectin, conserved site [IPR018378] 0.8452058911932679 1.3181853372386925 0.1874416127352818 1.0 0.4956388798288701 2 Q9UBG0 1 +Intermediate filament protein, conserved site [IPR018039] 0.5836940043204155 1.2160689699134208 0.223958649869659 1.0 0.5227691725917821 8 P08670,P07196 2 +Methylthiotransferase, conserved site [IPR020612] 0.8151487826870957 1.1955907587819083 0.2318562994889956 1.0 0.5323999203569962 2 Q5VV42 1 +Immunoglobulin/major histocompatibility complex, conserved site [IPR003006] 0.8103396453261168 1.1760713510050298 0.2395663650537396 1.0 0.5385020741473621 2 P04439 1 +Tetraspanin, conserved site [IPR018503] 0.839278149833835 1.1621857678919758 0.2451600144400165 1.0 0.5393520317680365 3 O43657 1 +Guanylate kinase, conserved site [IPR020590] 0.6354123378081854 1.033455954719826 0.3013905725268491 1.0 0.5900549796881295 5 Q14168 1 +Glycoside hydrolase, family 29, conserved site [IPR018526] 0.7598437030357483 0.9736853915185676 0.3302127728982911 1.0 0.6053900836468671 2 Q9BTY2 1 +Dynamin, GTPase region, conserved site [IPR019762] 0.7081454764051706 0.7742663452670719 0.4387733014047337 1.0 0.6802467830117492 2 O00429 1 +Homeobox, conserved site [IPR017970] 0.6762849413886243 0.6575793676567618 0.51080845594598 1.0 0.7496259326038072 2 P35453 1 +Clathrin adaptor complex, small chain [IPR000804] 0.6696723775172831 0.6341309949488735 0.5259953365179979 1.0 0.7573231284944996 2 P61923 1 +Phosphatidylinositol 3/4-kinase, conserved site [IPR018936] 0.4904307861052397 0.5418993256364207 0.5878878613598084 1.0 0.7965264303583869 6 P42356 1 +Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726] 0.6083558761647112 0.4329541800099243 0.665048057744136 1.0 0.83131007218017 2 Q07812 1 +Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728] 0.6083558761647112 0.4329541800099243 0.665048057744136 1.0 0.83131007218017 2 Q07812 1 +Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717] 0.6083558761647112 0.4329541800099243 0.665048057744136 1.0 0.83131007218017 2 Q07812 1 +RNA polymerase, beta subunit, conserved site [IPR007121] 0.60414788097384 0.4204063293832003 0.6741886451188714 1.0 0.8389225222067406 2 P30876 1 +ABC transporter-like, conserved site [IPR017871] 0.4012703803566901 0.4115558702285614 0.680664982620439 1.0 0.8396579239260222 9 Q03518 1 +14-3-3 protein, conserved site [IPR023409] 0.4363526933493882 0.3443635797575755 0.7305728749219027 1.0 0.8585792333483899 6 P61981,P27348,P63104,P62258,Q04917 5 +Dynein light chain, type 1/2, conserved site [IPR019763] 0.5716862037872026 0.3300877929867153 0.7413336265801576 1.0 0.863842149616709 2 Q96FJ2 1 +Heat shock protein Hsp90, conserved site [IPR019805] 0.5505111244738319 0.2473463292112794 0.8046402068741205 1.0 0.903167579144421 3 P14625,P07900 2 +Chromo domain, conserved site [IPR023779] 0.4763909774436118 0.2342593344446463 0.8147836540059661 1.0 0.9068695481817992 4 Q13185,P83916,P45973 3 +HMG box A DNA-binding domain, conserved site [IPR017967] 0.5336740829825575 0.2129917806653934 0.8313333736761817 1.0 0.9144667110437998 3 P26583,O15347 2 +IMP dehydrogenase / GMP reductase, conserved site [IPR015875] 0.508265704839207 0.1910077773588506 0.8485194998911771 1.0 0.92596373996061 2 P12268 1 +DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514] 0.4959422903516644 0.1701561649840887 0.8648873241983186 1.0 0.9324734836793014 2 O15160 1 +Thioredoxin, conserved site [IPR017937] 0.3229886211710366 0.1444116574294752 0.8851754120026056 1.0 0.9362432242335252 13 O43396,Q9H1E5,O95881 3 +Glycosyl hydrolases family 31, conserved site [IPR030459] 0.4283137962127976 0.0902212948187578 0.9281113625161486 1.0 0.9653588858024892 2 P10253 1 +Histidine triad, conserved site [IPR019808] 0.4186955214908319 0.083108430754849 0.9337653222671348 1.0 0.9653588858024892 2 Q96C86 1 +Mitogen-activated protein (MAP) kinase, conserved site [IPR003527] 0.361329264957037 0.0351463194130999 0.9719630666580276 1.0 0.9864272122915236 3 P28482 1 diff --git a/interpro_conserved_site/selections.json b/interpro_conserved_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..1634cf9f5c7f22cfd153af3ecaf2540646cac1b2 --- /dev/null +++ b/interpro_conserved_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Clusterin, conserved site [IPR033986]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "Dihydroorotate dehydrogenase, conserved site [IPR001295]", "DnaJ domain, conserved site [IPR018253]", "Dpy-30 motif [IPR007858]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FHF complex subunit HOOK interacting protein, KELAA motif [IPR045668]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "GoLoco motif [IPR003109]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Helix-turn-helix motif [IPR000047]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Homeobox, conserved site [IPR017970]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Pseudouridine synthase, RluC/RluD, conserved site [IPR006224]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Pyridoxamine 5'-phosphate oxidase, conserved site [IPR019740]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Rel homology domain, conserved site [IPR030492]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class II, conserved site [IPR002011]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]"], "available_proteins": ["AAAS", "AACS", "AAMP", "ABCB1", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK3", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP2S1", "AP3M1", "APEX1", "ARIH2", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "BAG6", "BAX", "BAZ1A", "BAZ1B", "BCAT2", "BCS1L", "BDH2", "BLM", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD2", "BRD4", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAP2", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDH2", "CDK5RAP1", "CDKAL1", "CDX2", "CECR2", "CENPE", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD4", "CLGN", "CLU", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1B", "CORO1C", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYP51A1", "DCAF7", "DCP2", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHODH", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DIS3L2", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC21", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DPY30", "DRG1", "DRG2", "DSC3", "DSG2", "DST", "DTL", "DTYMK", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "EIF4E2", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L5", "EPDR1", "EPN1", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FAM160A2", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FUCA1", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLO1", "GMPPA", "GMPPB", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GPSM1", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GTF3C2", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HOXD13", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA6", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IGF1R", "ILVBL", "IMPA1", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INTS12", "IQGAP1", "IQGAP2", "IVD", "KDM2A", "KDSR", "KIF11", "KIF14", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIFC1", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LDLR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRP1", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME2", "MGST2", "MID1", "MIF", "MKRN2", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPST", "MRC2", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "MVK", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFL", "NEFM", "NES", "NFKB1", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD1", "NSD2", "NSF", "NSUN6", "NUBPL", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF2", "PHF3", "PHF8", "PHGDH", "PHIP", "PI4KA", "PI4KB", "PIK3C2A", "PIK3C3", "PIN1", "PLEC", "PLOD1", "PLOD2", 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sha256:a77f7a06002041516d75c4ad7bfac3f859f59f7a48d140ab50a4f0fb7a52a633 +size 371884 diff --git a/interpro_domain/df_merge.tsv b/interpro_domain/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..b2ee98bd36c8b836951e78b55aafd59d79fad7b7 --- /dev/null +++ b/interpro_domain/df_merge.tsv @@ -0,0 +1,4 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179] 6 10 2.7295817213392204 0.0063414729438826 3.1262135922330097 10.111650485436892 0.9686720267359892 0.3700536707457866 1.7316562118191232 1.203619216216406 0.9607394322697528 0.3108814801432357 0.0001304500459516 3.066034551708988e-05 5.5913743904608274e-06 7.014604493490859e-09 8.443744114806333e-07 +Cytochrome b5-like heme/steroid binding domain [IPR001199] 3 5 2.1224466154658232 0.0338002511723951 2.813106796116505 6.104368932038835 1.6405397264547834 0.1100883340733615 1.2852875686886795 0.8042848477475721 1.100790504333474 0.1612592696854457 0.0039071928268104 0.0573151884822011 0.0057815105752346 0.0001450038876457 0.0020333503076747 +Alcohol dehydrogenase, N-terminal [IPR013154] 0 5 1.9744548728715008 0.0483300438814899 1.3762135922330097 5.245145631067961 0.6000738304798152 0.3870290227769069 1.1994000251783288 0.9246362329357484 1.1062357688130569 0.3020782188917261 0.0692945510525022 0.0432957136582515 0.0841007109914387 0.1988473022417859 0.3629223192764827 diff --git a/interpro_domain/metrics.json b/interpro_domain/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..06566757f621b27aec4949df09341767949ad113 --- /dev/null +++ b/interpro_domain/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3329, + "annotations_size": 2693, + "title": "Average number of proteins per term", + "value": 2.1927218715187524 +} \ No newline at end of file diff --git a/interpro_domain/paths.json b/interpro_domain/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..00624edda8ed9229d712b6657285e43d834ef1c3 --- /dev/null +++ b/interpro_domain/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C342/C342_val_log2fc"} \ No newline at end of file diff --git a/interpro_domain/result.tsv b/interpro_domain/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..79ac6c28c2f13ccc6c88dcc4ff3b17a31bb9c937 --- /dev/null +++ b/interpro_domain/result.tsv @@ -0,0 +1,213 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179] 0.8834765937961775 2.7295817213392204 0.0063414729438826 0.9999999637187652 0.0954807901344428 10 P62942,P26885,Q9Y680,Q02790,Q96AY3,Q9NWM8 6 +Cytochrome b5-like heme/steroid binding domain [IPR001199] 0.9042777294053956 2.1224466154658232 0.0338002511723951 1.0 0.1482476814450491 5 O43169,O15173,Q9UMX5 3 +EF-hand domain [IPR002048] 0.4740321508317648 1.9061484977138503 0.0566309420274548 1.0 0.1983103699450978 49 Q9Y680,Q02818,Q66K14,Q0IIM8,Q96D71,O43852,P80303,Q96AY3,Q14257,Q9NWM8,O75340,O75071,P0DP25 13 +Peptidase M1, membrane alanine aminopeptidase [IPR014782] 0.8469948171244304 1.897298412488972 0.0577885644030908 1.0 0.1996060411491266 5 P55786,Q9UIQ6,Q9NZ08 3 +Aminopeptidase N-like , N-terminal domain [IPR045357] 0.8469948171244304 1.897298412488972 0.0577885644030908 1.0 0.1996060411491266 5 P55786,Q9UIQ6,Q9NZ08 3 +EXPERA domain [IPR033118] 0.9705440336639588 1.8317965011957436 0.0669817447227094 1.0 0.2181158869870091 2 Q5BJF2 1 +Polyketide synthase, enoylreductase domain [IPR020843] 0.7998876207933959 1.8262175224260544 0.0678175029643983 1.0 0.2195102589941403 6 P49327,Q8N4Q0 2 +Reticulon [IPR003388] 0.9193572784989376 1.8044970511955984 0.0711534210212603 1.0 0.2259624561441675 4 Q16799 1 +Glutathione S-transferase, N-terminal [IPR004045] 0.6797184304204351 1.7709880864012095 0.0765626828767522 1.0 0.2362430324035664 9 O15217 1 +Glutathione S-transferase, C-terminal [IPR004046] 0.6661540318415667 1.7674201917577808 0.0771578838385156 1.0 0.2374699213452829 11 O15217 1 +TRAM/LAG1/CLN8 homology domain [IPR006634] 0.9507063420498916 1.7508510435910751 0.0799715715275013 1.0 0.2408987048361981 2 Q15629 1 +Zinc finger, RanBP2-type [IPR001876] 0.6735948006834193 1.7417763447567731 0.0815475874809328 1.0 0.2421253065999471 9 Q01844,Q92804,P35637 3 +Isopropylmalate dehydrogenase-like domain [IPR024084] 0.8026898677752794 1.7198268020639045 0.0854639291467145 1.0 0.2509862172214855 5 P48735 1 +RBM3/CIRBP, RNA recognition motif [IPR034278] 0.9392846408175504 1.7041325275201098 0.0883563309887311 1.0 0.2552561655016699 2 P98179 1 +K Homology domain, type 1 [IPR004088] 0.5100141742180068 1.671598365259578 0.0946035473559667 1.0 0.2656593879349515 26 P51116,P61978,O75525,Q92945,Q96AE4,Q96I24,Q06787,P51114,Q9Y2W6 9 +YTH domain [IPR007275] 0.7895276701523062 1.6665954577874065 0.0955948726974802 1.0 0.2673281330989764 5 Q7Z739,Q9H6S0,Q9Y5A9 3 +Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547] 0.9242560865644736 1.6425593235928824 0.1004741425719304 1.0 0.2758173964793156 2 P13674 1 +Glutathione S-transferase, C-terminal-like [IPR010987] 0.602627524913507 1.6366967631730531 0.1016938456430232 1.0 0.2772082252493513 13 O15217 1 +Serine hydroxymethyltransferase-like domain [IPR039429] 0.91794409377818 1.6166708858695076 0.1059493416365748 1.0 0.2858933637548057 2 P34896 1 +Peptidase S9A, N-terminal domain [IPR023302] 0.908926961226326 1.579665935706802 0.1141833905981832 1.0 0.3000758132937635 2 P48147 1 +Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337] 0.9071235347159602 1.5722625067481373 0.1158896844632548 1.0 0.3026735887845719 2 O60506 1 +Fragile X-related 1 protein, C-terminal region 1 [IPR032172] 0.9047189660354692 1.5623902501382103 0.1181960825419401 1.0 0.3068655543235056 2 P51116 1 +GRAM domain [IPR004182] 0.8524408086204942 1.5486676438358018 0.1214616358073941 1.0 0.3123562586329474 4 Q0IIM8,Q969T9 2 +P-type ATPase, haloacid dehalogenase domain [IPR044492] 0.7539943771241531 1.5218790146467065 0.1280393982865071 1.0 0.3231050199685626 5 Q9NQ11,Q9HD20 2 +Oxoglutarate/iron-dependent dioxygenase [IPR005123] 0.6435135669571694 1.500317435768149 0.1335321950774033 1.0 0.3295663661994017 8 P13674,Q32P28 2 +GMP phosphodiesterase, delta subunit [IPR008015] 0.8893898406973129 1.4994376476561837 0.1337601330322859 1.0 0.3295663661994017 2 A6NIH7 1 +ERAP1-like C-terminal domain [IPR024571] 0.927841250751648 1.4911912070740985 0.1359113015556599 1.0 0.3312299865062372 3 Q9UIQ6,Q9NZ08 2 +Far upstream element-binding protein, C-terminal [IPR015096] 0.8818755635707864 1.4685767718898457 0.1419476189389166 1.0 0.3389385620109603 2 Q96AE4 1 +CARG-binding factor, N-terminal [IPR012956] 0.8785692816351078 1.4549996687837243 0.1456693531933812 1.0 0.345019848856443 2 Q99729 1 +Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375] 0.8271899567605905 1.4513077947052793 0.1466941717757355 1.0 0.3468370540755537 4 Q4J6C6,P48147 2 +CTP synthase, N-terminal [IPR017456] 0.8761647129546055 1.445126478636242 0.1484223627154777 1.0 0.3489773589957096 2 P17812 1 +CTP synthase GATase domain [IPR033828] 0.8761647129546055 1.445126478636242 0.1484223627154777 1.0 0.3489773589957096 2 P17812 1 +K Homology domain [IPR004087] 0.4761663750087711 1.3995767854872558 0.161640089688871 1.0 0.3714136190547181 25 P51116,P61978,O75525,Q92945,Q96AE4,Q96I24,Q06787,P51114,Q9Y2W6 9 +RNA recognition motif domain, eukaryote [IPR003954] 0.5402163989836916 1.3941502990198031 0.1632722227760483 1.0 0.3735701749667784 14 Q8TBF4,Q01081,Q14011,P11940,P38159,Q9UHX1,Q01085 7 +Zinc finger, CHHC-type [IPR012996] 0.8995790739627147 1.3860025648887626 0.1657461202970185 1.0 0.3760562407671241 3 P31943,P55795 2 +SH2 domain [IPR000980] 0.5953647413259646 1.3613336659705948 0.1734082684938505 1.0 0.3859408818627598 9 P46108,Q7KZ85 2 +PA domain [IPR003137] 0.8539224526600399 1.3538801892838987 0.1757746048240172 1.0 0.3886766095250415 2 Q8TCT8 1 +Prolyl 4-hydroxylase, alpha subunit [IPR006620] 0.6490163267404275 1.3532721229008873 0.1759687116221822 1.0 0.3886766095250415 7 P13674,Q32P28 2 +GYF domain [IPR003169] 0.8512173128944887 1.3427974854355331 0.1793375578573086 1.0 0.3945571057623834 2 O95400 1 +CD209-like, C-type lectin-like domain [IPR033989] 0.8452058911932679 1.3181853372386925 0.1874416127352818 1.0 0.4010423768317462 2 Q9UBG0 1 +C-type lectin-like [IPR001304] 0.8452058911932679 1.3181853372386925 0.1874416127352818 1.0 0.4010423768317462 2 Q9UBG0 1 +Target SNARE coiled-coil homology domain [IPR000727] 0.6045935474243659 1.3159135851364856 0.1882030485095212 1.0 0.4013684110493573 8 Q86Y82,O43752,O95721 3 +Exportin-2, central domain [IPR013713] 0.8780749404469471 1.306003144690019 0.1915514881651385 1.0 0.406179651676156 3 O95373 1 +Fxr1, tudor domain [IPR041560] 0.8767288033674043 1.3009993750924018 0.1932586686276542 1.0 0.4077172939388809 3 P51116,P51114 2 +Synaptic functional regulator FMRP, KH0 domain [IPR040472] 0.8767288033674043 1.3009993750924018 0.1932586686276542 1.0 0.4077172939388809 3 P51116,P51114 2 +Agenet-like domain [IPR008395] 0.8767288033674043 1.3009993750924018 0.1932586686276542 1.0 0.4077172939388809 3 P51116,P51114 2 +Fragile X-related 1 protein, C-terminal core [IPR022034] 0.8767288033674043 1.3009993750924018 0.1932586686276542 1.0 0.4077172939388809 3 P51116,P51114 2 +Intermediate filament head, DNA-binding domain [IPR006821] 0.785687800638013 1.2908482396415473 0.1967563065926114 1.0 0.4115456903335475 4 P08670,P07196 2 +Dynamin-type guanine nucleotide-binding (G) domain [IPR030381] 0.6326893090690588 1.2801097643531585 0.2005065350618209 1.0 0.4163177323989851 7 O60313 1 +Dynamin, N-terminal [IPR045063] 0.6326893090690588 1.2801097643531585 0.2005065350618209 1.0 0.4163177323989851 7 O60313 1 +GOLD domain [IPR009038] 0.6655566914527764 1.2670771174555462 0.2051277166730005 1.0 0.4216967438322965 6 Q15363 1 +Mad3/Bub1 homology region 1 [IPR013212] 0.8325819056206792 1.2665874329268605 0.2053028483290615 1.0 0.4216967438322965 2 O60566 1 +Small G protein signalling modulator 1/2, Rab-binding domain [IPR021935] 0.8313796212804307 1.2616805931878698 0.2070637428715884 1.0 0.4233515577282893 2 Q8TC07 1 +Peptidase M28 [IPR007484] 0.8541791942272973 1.2173061479460263 0.2234877560395243 1.0 0.4418887863542136 3 Q969V3,Q7Z2K6 2 +Intermediate filament, rod domain [IPR039008] 0.5836940043204155 1.2160689699134208 0.223958649869659 1.0 0.4419119278021088 8 P08670,P07196 2 +L27 domain [IPR004172] 0.762646733812635 1.201799560673226 0.2294411957283308 1.0 0.4477428551423152 4 Q14168 1 +L27 domain, C-terminal [IPR014775] 0.762646733812635 1.201799560673226 0.2294411957283308 1.0 0.4477428551423152 4 Q14168 1 +Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862] 0.762437135595667 1.2009903919304992 0.2297549283789481 1.0 0.4480304287650307 4 P13674,Q32P28 2 +Methylthiotransferase, N-terminal [IPR013848] 0.8151487826870957 1.1955907587819083 0.2318562994889956 1.0 0.4485553265257653 2 Q5VV42 1 +TRAM domain [IPR002792] 0.8151487826870957 1.1955907587819083 0.2318562994889956 1.0 0.4485553265257653 2 Q5VV42 1 +Radical SAM [IPR007197] 0.8151487826870957 1.1955907587819083 0.2318562994889956 1.0 0.4485553265257653 2 Q5VV42 1 +Elp3/MiaB/NifB [IPR006638] 0.8151487826870957 1.1955907587819083 0.2318562994889956 1.0 0.4485553265257653 2 Q5VV42 1 +Immunoglobulin-like domain [IPR007110] 0.5142066004325474 1.1512489224076006 0.2496298437940103 1.0 0.4699165819573803 13 P10321,P10586,P04439,Q9Y639,P35613 5 +Importin-beta, N-terminal domain [IPR001494] 0.5132910006513034 1.1461441474368752 0.2517355133598009 1.0 0.471763213276231 13 O95373,O15397,Q9HAV4,Q92973 4 +Armadillo repeat-containing domain [IPR006911] 0.8019236549443973 1.1419941130155786 0.2534564667091503 1.0 0.4736698576320207 2 Q8N2F6 1 +Pericentrin/AKAP-450 centrosomal targeting domain [IPR019528] 0.8016230838593355 1.1407791371563825 0.2539618445951817 1.0 0.4741019322658008 2 O95613 1 +Glutamine amidotransferase type 2 domain [IPR017932] 0.8245405702071451 1.1078773902197074 0.2679147713692882 1.0 0.4858548682138001 3 Q06210 1 +PABP, RNA recognition motif 2 [IPR045305] 0.7902013826269894 1.0947272592094206 0.2736361425707079 1.0 0.4932410521706267 2 P11940 1 +Zinc finger C2H2 AKAP95-type [IPR034736] 0.8205051112447317 1.0930502789867114 0.2743717247889545 1.0 0.4942361570947522 3 O43823,Q5BKZ1 2 +SUN coiled coil domain 2 [IPR040994] 0.7892996693718056 1.0911019332611975 0.2752280322650224 1.0 0.4944556977249537 2 O94901 1 +Legume-like lectin [IPR005052] 0.7865945296062349 1.080235708831364 0.2800372307453513 1.0 0.4979125069245987 2 P49257 1 +Tim44-like domain [IPR007379] 0.7847911030958854 1.072999892982385 0.2832711641469914 1.0 0.5012150098868908 2 Q9BRJ2 1 +Sam68, tyrosine-rich domain [IPR032335] 0.7835888187556177 1.0681798173558392 0.2854394069860606 1.0 0.5021434496525525 2 O75525 1 +KHDRBS, Qua1 domain [IPR032571] 0.7835888187556177 1.0681798173558392 0.2854394069860606 1.0 0.5021434496525525 2 O75525 1 +GPAT/DHAPAT, acyltransferase domain [IPR041728] 0.7826871055004534 1.064566791975326 0.2870720140885119 1.0 0.5021434496525525 2 O15228 1 +Glycerol-3-phosphate acyltransferase-like, C-terminal domain [IPR045520] 0.7826871055004534 1.064566791975326 0.2870720140885119 1.0 0.5021434496525525 2 O15228 1 +Peptidase M3A/M3B catalytic domain [IPR001567] 0.8126879134094951 1.0643896641822015 0.2871522140605016 1.0 0.5021434496525525 3 Q9BYT8,Q99797 2 +Rab-GTPase-TBC domain [IPR000195] 0.5312892946053379 1.0636311642709708 0.2874958188920247 1.0 0.502418066370034 10 O60343,Q66K14,Q8TC07,Q0IIM8,Q9BXI6 5 +Phox homology [IPR001683] 0.4973308306280906 1.057033631237736 0.2904962388721606 1.0 0.5043369980185521 13 Q96L92,Q9UMY4,Q9Y2I1 3 +MHC class I alpha chain, alpha1 alpha2 domains [IPR001039] 0.8105832832230833 1.056688171025116 0.2906539253341229 1.0 0.5043369980185521 3 P04439,P10321 2 +MHC class I, alpha chain, C-terminal [IPR010579] 0.8105832832230833 1.056688171025116 0.2906539253341229 1.0 0.5043369980185521 3 P04439,P10321 2 +MHC class I-like antigen recognition-like [IPR011161] 0.8105832832230833 1.056688171025116 0.2906539253341229 1.0 0.5043369980185521 3 P04439,P10321 2 +Immunoglobulin C1-set [IPR003597] 0.8105832832230833 1.056688171025116 0.2906539253341229 1.0 0.5043369980185521 3 P04439,P10321 2 +RNA recognition motif domain [IPR000504] 0.3874866991521339 1.0507594762853112 0.2933690719066462 1.0 0.5069721279697246 120 Q86V81,Q13242,P11940,P55795,Q14103,Q8IZ69,O60506,Q9BWF3,P98175,Q15056,Q8NDT2,O43347,Q8IY67,O43390,P31942,Q9UHX1,Q99729,Q13247,Q13310,Q96PK6,Q01085,P31943,A0AV96,Q07955,P22626,Q14011,P62995,O14979,P52597,P09651,Q13148,P26368,Q93062,Q8TBF4,Q01081,P51991,Q92804,Q01844,P38159,P98179,P23588,P35637 42 +CYRIA/CYRIB, Rac1 binding domain [IPR009828] 0.8024654239326374 1.027046612672476 0.3043985157169673 1.0 0.5165376199280359 3 Q7L576,Q9NUQ9 2 +Fibronectin type II domain [IPR000562] 0.7958508719182146 1.0029756496320632 0.3158726101925211 1.0 0.5271471059981332 3 Q9UBG0,P11717 2 +SPRY domain [IPR003877] 0.4859774049837958 0.9935559714011444 0.3204390882874879 1.0 0.5284399661715891 13 P19474 1 +B30.2/SPRY domain [IPR001870] 0.4859774049837958 0.9935559714011444 0.3204390882874879 1.0 0.5284399661715891 13 P19474 1 +Polyadenylate-binding protein/Hyperplastic disc protein [IPR002004] 0.7904389657245894 0.9833405976480414 0.3254398355718244 1.0 0.5289248429026316 3 O95071,P11940 2 +Alpha-L-fucosidase, C-terminal [IPR031919] 0.7598437030357483 0.9736853915185676 0.3302127728982911 1.0 0.5312704832319135 2 Q9BTY2 1 +Peptidase C1A, papain C-terminal [IPR000668] 0.757439134355258 0.9641998448292228 0.334945742169364 1.0 0.5349962919020638 2 P07858 1 +Homeobox domain [IPR001356] 0.700477686802075 0.9635190530015708 0.3352871073108385 1.0 0.5349962919020638 4 Q96G23 1 +MD-2-related lipid-recognition domain [IPR003172] 0.757138563270203 0.963015348887208 0.3355398206545064 1.0 0.5349962919020638 2 P17900 1 +DNA2/NAM7 helicase-like, C-terminal [IPR041679] 0.6999096171283062 0.9613659827595432 0.3363681820509372 1.0 0.5359997125817597 4 P51530 1 +Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778] 0.7781923142520087 0.9391265838323924 0.3476657569323294 1.0 0.5484849932154441 3 Q9BUJ2 1 +OCRE domain [IPR041591] 0.7397054403366192 0.894806317313646 0.3708906327383388 1.0 0.5675048147524695 2 P98175 1 +Phospholipid/glycerol acyltransferase [IPR002123] 0.6816242111963634 0.892415481194858 0.3721702762402419 1.0 0.5684346634189137 4 O15228,Q9HCL2 2 +EB1, C-terminal [IPR004953] 0.7388037270814363 0.8913064237680492 0.372764803415448 1.0 0.5684346634189137 2 Q15555 1 +PTB/PI domain [IPR006020] 0.6770311221536602 0.8752160143540325 0.3814563812436127 1.0 0.5775102434669152 4 O60343 1 +Cold shock domain [IPR011129] 0.5891307461829052 0.844965893609257 0.398129881962461 1.0 0.5920285875896784 5 P16989 1 +Cold-shock protein, DNA-binding [IPR002059] 0.5891307461829052 0.844965893609257 0.398129881962461 1.0 0.5920285875896784 5 P16989 1 +Hexokinase, N-terminal [IPR022672] 0.7171626089570039 0.8082651094792781 0.4189379833195228 1.0 0.6065591339136962 2 P52789 1 +Hexokinase, C-terminal [IPR022673] 0.7171626089570039 0.8082651094792781 0.4189379833195228 1.0 0.6065591339136962 2 P52789 1 +LEM domain [IPR003887] 0.5497517726172032 0.7796704469000352 0.4355848783710894 1.0 0.6193277710537687 6 Q86XL3 1 +Major facilitator superfamily domain [IPR020846] 0.651155424736652 0.7794294563991248 0.4357267775929241 1.0 0.6193277710537687 4 Q6NT16 1 +GTPase effector domain [IPR020850] 0.7081454764051706 0.7742663452670719 0.4387733014047337 1.0 0.6193277710537687 2 O00429 1 +Dynamin GTPase effector [IPR003130] 0.7081454764051706 0.7742663452670719 0.4387733014047337 1.0 0.6193277710537687 2 O00429 1 +Dynamin stalk domain [IPR000375] 0.7081454764051706 0.7742663452670719 0.4387733014047337 1.0 0.6193277710537687 2 O00429 1 +ATPase family AAA domain-containing protein 3, N-terminal [IPR021911] 0.7003306281935697 0.7451237197495527 0.4561969310210139 1.0 0.6348869650420814 2 Q5T9A4 1 +Nucleotidyl transferase domain [IPR005835] 0.7221888153938527 0.7420742844567905 0.4580423293667484 1.0 0.6359138243788932 3 Q96IJ6,Q9Y5P6 2 +Survival motor neuron [IPR010304] 0.6991283438533207 0.7406683432058885 0.4588945582940122 1.0 0.6359138243788932 2 O75940 1 +SUN domain [IPR012919] 0.7201113773652703 0.7349697460498815 0.4623579195927552 1.0 0.6375473002884228 3 O94901 1 +Immunoglobulin subtype [IPR003599] 0.4682067343751429 0.7288184924038705 0.4661126981861931 1.0 0.6407562512585084 9 Q9Y639 1 +Immunoglobulin subtype 2 [IPR003598] 0.4682067343751429 0.7288184924038705 0.4661126981861931 1.0 0.6407562512585084 9 Q9Y639 1 +Syntaxin, N-terminal domain [IPR006011] 0.7140709561034183 0.7144132945972261 0.4749716535670969 1.0 0.6499485076505042 3 Q86Y82,O15400 2 +Proteasome alpha-subunit, N-terminal domain [IPR000426] 0.5048896297438696 0.7087329033403902 0.4784902422247099 1.0 0.6527731622650171 7 P25786 1 +Exosome complex component, N-terminal domain [IPR025721] 0.6874060715359183 0.6976458831460186 0.4853986795753848 1.0 0.65769483190654 2 Q13868 1 +Dynamin, GTPase domain [IPR001401] 0.7083583884545824 0.6951163969372178 0.4869823597555294 1.0 0.65769483190654 3 O00429,O60313 2 +Phosphoinositide 3-kinase, accessory (PIK) domain [IPR001263] 0.6273335116662428 0.6932993625895307 0.4881217029813354 1.0 0.6587201692877293 4 P42356 1 +Diacylglycerol kinase, catalytic domain [IPR001206] 0.6795912233243011 0.669410599809264 0.5032335918260855 1.0 0.6692385495247646 2 Q9NRA0 1 +Zinc finger, UBR-type [IPR003126] 0.6952070975589235 0.6512617603068821 0.5148775285492071 1.0 0.6767935402197568 3 Q8IWV7 1 +ABC transporter type 1, transmembrane domain [IPR011527] 0.5347320263376567 0.630981527554579 0.5280526027815833 1.0 0.6862937314481394 5 Q03518 1 +Guanylate kinase/L-type calcium channel beta subunit [IPR008145] 0.4814023161272779 0.6074894615461711 0.543526134273911 1.0 0.6937708955540152 7 Q14168 1 +Guanylate kinase-like domain [IPR008144] 0.4814023161272779 0.6074894615461711 0.543526134273911 1.0 0.6937708955540152 7 Q14168 1 +SH3 domain [IPR001452] 0.3543598507315651 0.5883787032465624 0.5562781292143313 1.0 0.7021735249124722 33 P62993,Q9UQB8,Q92783,P46108,Q14168,Q9NZW5 6 +Cation-transporting P-type ATPase, N-terminal [IPR004014] 0.6707757065544068 0.5721631655865278 0.5672114392862828 1.0 0.7069645171502856 3 P16615,P05023 2 +Cation-transporting P-type ATPase, C-terminal [IPR006068] 0.6707757065544068 0.5721631655865278 0.5672114392862828 1.0 0.7069645171502856 3 P16615,P05023 2 +HDGF-related, PWWP domain [IPR035496] 0.6702754362583389 0.5705789474971847 0.5682850925533456 1.0 0.7069645171502856 3 P51858 1 +Cold-shock (CSD) domain [IPR019844] 0.5899146877974333 0.563362076848973 0.5731883551750578 1.0 0.7096994209133015 4 P16989 1 +Glutamine amidotransferase [IPR017926] 0.5875171571863147 0.5553065146284332 0.5786850236349088 1.0 0.7128997111842678 4 P17812 1 +NudC N-terminal domain [IPR025934] 0.6278929966937106 0.4935079246769616 0.6216537417932599 1.0 0.7390226473979638 2 Q8IVD9 1 +Band 7 domain [IPR001107] 0.4284853959650767 0.4855894758295176 0.6272582596353 1.0 0.7419125976348222 8 O94905,P35232,Q99623,O75477,O75955,Q9UJZ1,P27105 7 +Zinc finger, CCHC-type [IPR001878] 0.4157059179530634 0.4774311223815416 0.6330551567737592 1.0 0.7444618066339448 9 Q8TBF4,Q9NUD5 2 +Post-SET domain [IPR003616] 0.6324105240944986 0.4554546112883145 0.6487822142242394 1.0 0.7521181674153581 3 O96028 1 +p21 activated kinase binding domain [IPR033923] 0.6253758268189908 0.4352123743836871 0.6634082813730646 1.0 0.7647938791685202 3 Q13177,Q13153 2 +DNA-directed RNA polymerase, subunit 2, hybrid-binding domain [IPR007120] 0.60414788097384 0.4204063293832003 0.6741886451188714 1.0 0.7714496218754491 2 P30876 1 +RNA polymerase Rpb2, domain 2 [IPR007642] 0.60414788097384 0.4204063293832003 0.6741886451188714 1.0 0.7714496218754491 2 P30876 1 +RNA polymerase, beta subunit, protrusion [IPR007644] 0.60414788097384 0.4204063293832003 0.6741886451188714 1.0 0.7714496218754491 2 P30876 1 +RNA polymerase Rpb2, domain 3 [IPR007645] 0.60414788097384 0.4204063293832003 0.6741886451188714 1.0 0.7714496218754491 2 P30876 1 +RNA polymerase Rpb2, domain 7 [IPR007641] 0.60414788097384 0.4204063293832003 0.6741886451188714 1.0 0.7714496218754491 2 P30876 1 +Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403] 0.4358200485677166 0.4202017652473448 0.6743380653155615 1.0 0.7714496218754491 7 P42356 1 +CRIB domain [IPR000095] 0.4742845401369182 0.4120927136027575 0.6802714691115008 1.0 0.7758474232711965 5 Q9Y5S2 1 +ABC transporter-like, ATP-binding domain [IPR003439] 0.4012703803566901 0.4115558702285614 0.680664982620439 1.0 0.7758474232711965 9 Q03518 1 +BAG domain [IPR003103] 0.5407414367715864 0.4063509678510131 0.684484741133907 1.0 0.7771110631567604 4 O95429,Q9UL15 2 +Ubiquitin system component CUE [IPR003892] 0.540451127819552 0.4054813512410884 0.6851237236502394 1.0 0.7771110631567604 4 Q9H1I8,Q9H4L7,Q9Y679 3 +Glycosyltransferase 2-like [IPR001173] 0.4660048134777331 0.3843960323301021 0.7006849408081743 1.0 0.7894796221673963 5 Q10471,O60762,Q10472,Q9Y673 4 +Heat shock protein DnaJ, cysteine-rich domain [IPR001305] 0.5923030667468328 0.3456251747601633 0.7296244239449428 1.0 0.8122689432342831 3 O60884,P31689 2 +14-3-3 domain [IPR023410] 0.4363526933493882 0.3443635797575755 0.7305728749219027 1.0 0.812988740563919 6 P61981,P27348,P63104,P62258,Q04917 5 +Alpha-ketoglutarate-dependent dioxygenase AlkB-like [IPR027450] 0.5728884881274502 0.3332173867900494 0.7389701946159715 1.0 0.8189492732925149 2 Q6P6C2 1 +NUC153 [IPR012580] 0.5713856327021393 0.3293080992778094 0.7419228228882553 1.0 0.8208702391282134 2 Q9BSC4 1 +Tim10-like [IPR004217] 0.585387853277199 0.328149659886454 0.7427985077552739 1.0 0.8215015939979271 3 Q9Y5J9,O60220 2 +Damage-control phosphatase ARMT1-like, metal-binding domain [IPR002791] 0.5704839194469524 0.3269755281669845 0.7436863944695427 1.0 0.822145919666042 2 Q9H993 1 +FKBP3, basic tilted helix bundle domain [IPR041200] 0.5680793507664645 0.3208032809614817 0.7483594728646439 1.0 0.826972531975579 2 Q00688 1 +EF-hand, Ca insensitive [IPR014837] 0.5091729323308305 0.3164590793867615 0.7516540802656648 1.0 0.8302725341080539 4 Q13813,P12814,O43707 3 +MRH domain [IPR044865] 0.5782946962176396 0.310707794007214 0.7560227715757175 1.0 0.8336155772628934 3 P20645 1 +LEM-like domain [IPR013146] 0.5626690712353516 0.3071732242286506 0.7587115249215142 1.0 0.835995925326405 2 P42167 1 +Amine oxidase [IPR002937] 0.5765859940852004 0.3065808077765676 0.7591624637687324 1.0 0.835995925326405 3 Q8NB78 1 +Sterile alpha motif domain [IPR001660] 0.4336340545080198 0.2829890122104582 0.7771852598704037 1.0 0.848382612416294 5 Q9Y6Y8 1 +AMPK, C-terminal adenylate sensor domain [IPR032270] 0.5524496543432542 0.2824189545982453 0.7776222826380255 1.0 0.8485157241265002 2 P54646 1 +Ricin B, lectin domain [IPR000772] 0.4310070504322283 0.2752883493808228 0.7830947146566181 1.0 0.8524147399233114 5 Q9UBG0 1 +LsmAD domain [IPR009604] 0.5422302374511628 0.2589923864702873 0.795641114846213 1.0 0.8628165285215537 2 Q99700 1 +Ataxin 2, SM domain [IPR025852] 0.5422302374511628 0.2589923864702873 0.795641114846213 1.0 0.8628165285215537 2 Q99700 1 +Heat shock protein Hsp90, N-terminal [IPR020575] 0.4769924812030113 0.2356555207535914 0.8136999871484265 1.0 0.8786263293467171 4 P08238,P14625,P07900 3 +JAB1/MPN/MOV34 metalloenzyme domain [IPR000555] 0.3647355056095712 0.2251695997447675 0.8218473380877815 1.0 0.8831743341861116 8 O95630 1 +Hotdog acyl-CoA thioesterase (ACOT)-type domain [IPR033120] 0.5220919747520364 0.2168268611676998 0.8283432777153892 1.0 0.8883824957736133 2 O00154 1 +NECAP, PHear domain [IPR012466] 0.5202885482416645 0.2133137856710872 0.8310822215892155 1.0 0.8906105940070662 2 Q9NVZ3 1 +Cysteine-rich flanking region, C-terminal [IPR000483] 0.5124737000300634 0.1985941866663079 0.8425802014049295 1.0 0.9018555176404908 2 Q13641 1 +Leucine-rich repeat N-terminal domain [IPR000372] 0.5124737000300634 0.1985941866663079 0.8425802014049295 1.0 0.9018555176404908 2 Q13641 1 +IMP dehydrogenase/GMP reductase [IPR001093] 0.508265704839207 0.1910077773588506 0.8485194998911771 1.0 0.9039015083888212 2 P12268 1 +Alpha-D-phosphohexomutase, C-terminal [IPR005843] 0.5070634204989469 0.188883896383885 0.8501838152107271 1.0 0.9053163362445584 2 O95394 1 +JmjC domain [IPR003347] 0.36751424547723 0.1778488350715698 0.858841693816967 1.0 0.9120113097196736 7 Q9H6W3 1 +Chromo shadow domain [IPR008251] 0.5132291040288572 0.1755625515122462 0.8606376248785399 1.0 0.9131982363269928 3 Q13185,P45973 2 +Chromo domain subgroup [IPR017984] 0.5132291040288572 0.1755625515122462 0.8606376248785399 1.0 0.9131982363269928 3 Q13185,P45973 2 +DNA-directed RNA polymerase, RpoA/D/Rpb3-type [IPR011263] 0.4959422903516644 0.1701561649840887 0.8648873241983186 1.0 0.9155430676360344 2 O15160 1 +DNA-directed RNA polymerase, insert domain [IPR011262] 0.4959422903516644 0.1701561649840887 0.8648873241983186 1.0 0.9155430676360344 2 O15160 1 +HTH CenpB-type DNA-binding domain [IPR006600] 0.4950405770964909 0.1687101183338281 0.8660246595923073 1.0 0.9160268689246204 2 Q7Z3K3 1 +DDE superfamily endonuclease domain [IPR004875] 0.4950405770964909 0.1687101183338281 0.8660246595923073 1.0 0.9160268689246204 2 Q7Z3K3 1 +SET domain [IPR001214] 0.3883865503155594 0.1631315474094617 0.8704148612504394 1.0 0.9199478890688514 5 O96028 1 +Zinc finger, LIM-type [IPR001781] 0.3372513562387143 0.1536340860789716 0.877898259194543 1.0 0.9249306825626976 11 Q9UHB6,Q53GG5,Q16527,Q96HC4,Q8N3F8,Q9UGI8,Q14847,Q9NR12,Q15942,Q13642 10 +Peroxiredoxin, C-terminal [IPR019479] 0.4301322558726993 0.1404265663657539 0.8883229688911054 1.0 0.9335061365232284 4 P30048 1 +Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant [IPR000866] 0.4301322558726993 0.1404265663657539 0.8883229688911054 1.0 0.9335061365232284 4 P30048 1 +EF hand associated, type-2 [IPR013567] 0.4676886083558834 0.129915351607464 0.8966333983992543 1.0 0.9399119275551544 2 Q8IXI2 1 +MIRO domain [IPR020860] 0.4676886083558834 0.129915351607464 0.8966333983992543 1.0 0.9399119275551544 2 Q8IXI2 1 +EF hand associated, type-1 [IPR013566] 0.4676886083558834 0.129915351607464 0.8966333983992543 1.0 0.9399119275551544 2 Q8IXI2 1 +BAT2, N-terminal [IPR009738] 0.4780517137702758 0.1223514454766719 0.9026206904108574 1.0 0.9439835026316268 3 Q5JSZ5,P48634 2 +Kinesin-like [IPR022164] 0.4595731890592231 0.1202410844909098 0.9042921731307204 1.0 0.9453644496277288 2 O60333 1 +R3H domain [IPR001374] 0.4759470835838696 0.1196130697196465 0.9047896659219774 1.0 0.945517489455912 3 Q9H6S0,O95453 2 +Sec63 domain [IPR004179] 0.474443776307868 0.117687331755869 0.906315404813924 1.0 0.9467445248890214 3 Q9UGP8,Q8N3C0 2 +Rhodanese-like domain [IPR001763] 0.4132330827067707 0.1130219290844471 0.9100131697110564 1.0 0.9495023115195176 4 P25325,Q99956,Q8NCN5 3 +N-acetylgalactosaminyltransferase [IPR045885] 0.4657245941070276 0.1070107575886526 0.9147804454415568 1.0 0.9530566015748696 3 Q10471,Q10472 2 +Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564] 0.46452194828623 0.1056034977711625 0.9158969494525668 1.0 0.9530566015748696 3 Q13505,O75431 2 +Metaxin, glutathione S-transferase domain [IPR033468] 0.46452194828623 0.1056034977711625 0.9158969494525668 1.0 0.9530566015748696 3 Q13505,O75431 2 +SCP2 sterol-binding domain [IPR003033] 0.4530968129885582 0.0930095813536375 0.9258959494014936 1.0 0.959383528948912 3 P51659,Q6YN16 2 +v-SNARE, coiled-coil homology domain [IPR042855] 0.4515935057125729 0.0914553508159898 0.9271307823860122 1.0 0.9599243356268862 3 O15498,O75396 2 +Longin domain [IPR010908] 0.4515935057125729 0.0914553508159898 0.9271307823860122 1.0 0.9599243356268862 3 O15498,O75396 2 +Glycoside hydrolase family 31, N-terminal domain [IPR025887] 0.4283137962127976 0.0902212948187578 0.9281113625161486 1.0 0.9604649738404136 2 P10253 1 +SAM domain [IPR041418] 0.4253080853621933 0.0878986465545212 0.929957232335216 1.0 0.9610033870601448 2 Q9NZI7 1 +CP2 transcription factor [IPR007604] 0.4253080853621933 0.0878986465545212 0.929957232335216 1.0 0.9610033870601448 2 Q9NZI7 1 +Transcription factor CBF/NF-Y/archaeal histone domain [IPR003958] 0.447553215688742 0.0873944153826197 0.9303580082747908 1.0 0.9610487596026128 3 Q9NR33 1 +CTLH/CRA C-terminal to LisH motif domain [IPR024964] 0.423631990378835 0.0666804465097465 0.946836101085858 1.0 0.9748330901771224 3 Q9H871,Q9NWU2 2 +CRA domain [IPR013144] 0.423631990378835 0.0666804465097465 0.946836101085858 1.0 0.9748330901771224 3 Q9H871,Q9NWU2 2 +GINS subunit, domain A [IPR021151] 0.377817853922444 0.0620312337297699 0.9505379589682944 1.0 0.9777688019486696 2 Q9BRT9 1 +Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain [IPR004099] 0.4107035478051607 0.0576987224443023 0.9539886113444018 1.0 0.9805692100574328 3 Q16881,P09622 2 +Ataxin-2, C-terminal [IPR009818] 0.3294223826714804 0.0523655100104603 0.9582374554192998 1.0 0.9845606514476056 5 Q9BPZ3,Q9H074,Q8WWM7,Q99700 4 +CS domain [IPR007052] 0.3075484212684653 0.0509631657588299 0.9593548718534732 1.0 0.9845818101758396 9 Q9HB71,Q9P035,Q15185,Q96RS6,Q8IVD9 5 +Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type [IPR003617] 0.3971737823211123 0.0497973489013412 0.960283879334197 1.0 0.9847846485327466 3 Q96QC0,P23193 2 +PTBP1, RNA recognition motif 2-like [IPR021790] 0.3536842105263198 0.0449537479890179 0.9641441754133904 1.0 0.9872396442540914 4 Q8WVV9,Q9UKA9,P14866 3 +DZF domain [IPR006561] 0.3518796992481244 0.0435299223444525 0.9652791125440844 1.0 0.9880260927712732 4 Q96SI9,Q96KR1,Q12906 3 +TRIAD supradomain [IPR044066] 0.3728915062048832 0.038987208700974 0.9689005868388638 1.0 0.9901939127347742 3 Q9UBS8 1 +IBR domain [IPR002867] 0.3728915062048832 0.038987208700974 0.9689005868388638 1.0 0.9901939127347742 3 Q9UBS8 1 +Exoribonuclease, phosphorolytic domain 2 [IPR015847] 0.2873044524669121 0.0052616394856671 0.9958018384607964 1.0 1.0 5 Q8TCS8,Q15024,Q9NQT4,Q96B26 4 +Immunoglobulin I-set [IPR013098] 0.2348118531515099 0.0035398720705365 0.9971755966263254 1.0 1.0 4 P10586 1 diff --git a/interpro_domain/selections.json b/interpro_domain/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..a4045dafdb00b61f377372eeb15492c263e2d230 --- /dev/null +++ b/interpro_domain/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, SH3 domain [IPR035724]", "10TM putative phosphate transporter, cytosolic domain [IPR027815]", "116kDa U5 small nuclear ribonucleoprotein component, C-terminal [IPR035655]", "116kDa U5 small nuclear ribonucleoprotein component, N-terminal [IPR031950]", "14-3-3 domain [IPR023410]", "18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23, C-terminal [IPR022238]", "2-oxoacid dehydrogenase acyltransferase, catalytic domain [IPR001078]", "2-oxoglutarate dehydrogenase E1 component, N-terminal domain [IPR032106]", "26S proteasome non-ATPase regulatory subunit RPN1, C-terminal [IPR041433]", "26S proteasome regulatory subunit RPN2, C-terminal [IPR040623]", "26S proteasome regulatory subunit RPN5, C-terminal domain [IPR040896]", "26S proteasome regulatory subunit Rpn6, N-terminal [IPR040773]", "26S proteasome regulatory subunit Rpn7, N-terminal [IPR045135]", "26S proteasome regulatory subunit, C-terminal [IPR013586]", "2Fe-2S ferredoxin-type iron-sulfur binding domain [IPR001041]", "3'-5' exonuclease domain [IPR002562]", "3-beta hydroxysteroid dehydrogenase/isomerase [IPR002225]", "3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108]", "3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176]", "3-hydroxyisobutyrate dehydrogenase, NAD-binding domain [IPR029154]", "3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal [IPR001104]", "3-oxoacid CoA-transferase, subunit A [IPR012792]", "3-oxoacid CoA-transferase, subunit B [IPR012791]", "4'-phosphopantetheinyl transferase domain [IPR008278]", "40S ribosomal protein S11, N-terminal [IPR032440]", "40S ribosomal protein S4, C-terminal domain [IPR032277]", "40S ribosomal protein SA, C-terminal domain [IPR032281]", "4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896]", "5'-AMP-activated protein kinase alpha 1 catalytic subunit, C-terminal [IPR039137]", "5'-AMP-activated protein kinase catalytic subunit alpha-2, C-terminal [IPR039148]", "6-phosphogluconate dehydrogenase, C-terminal [IPR006114]", "6-phosphogluconate dehydrogenase, NADP-binding [IPR006115]", "6-phosphogluconolactonase, DevB-type [IPR005900]", "60S ribosomal protein L10P, insertion domain [IPR040637]", "60S ribosomal protein L4, C-terminal domain [IPR025755]", "6S proteasome subunit Rpn6, C-terminal helix domain [IPR040780]", "A kinase-anchoring protein AKAP5 and AKAP12, calmodulin (CaM)-binding motif [IPR001573]", "AAA ATPase, AAA+ lid domain [IPR041569]", "AAA+ ATPase domain [IPR003593]", "AAR2, C-terminal [IPR033648]", "AAR2, N-terminal [IPR033647]", "AARP2CN [IPR012948]", "AATF leucine zipper-containing domain [IPR025160]", "ABC transporter type 1, transmembrane domain [IPR011527]", "ABC transporter-like, ATP-binding domain [IPR003439]", "ABC-transporter extension domain [IPR032781]", "ABC1 atypical kinase-like domain [IPR004147]", "ABT1/ESF2, RNA recognition motif [IPR034353]", "ADAM10/ADAM17 catalytic domain [IPR034025]", "ADAM17, membrane-proximal domain [IPR032029]", "ADAR1, first double-stranded RNA binding domain [IPR044456]", "ADAR1, third double-stranded RNA binding domain [IPR044457]", "ADCK3-like domain [IPR034646]", "ADD domain [IPR025766]", "ADNP, zinc finger domain [IPR045762]", "AGC-kinase, C-terminal [IPR000961]", "AIMP2, lysyl-tRNA synthetase binding domain [IPR031889]", "AIMP2, thioredoxin-like domain [IPR041503]", "ALIX V-shaped domain [IPR025304]", "AMP-binding enzyme, C-terminal domain [IPR025110]", "AMP-dependent synthetase/ligase [IPR000873]", "AMPK, C-terminal adenylate sensor domain [IPR032270]", "AP complex, mu/sigma subunit [IPR022775]", "AP-2 complex subunit mu, N-terminal [IPR043532]", "AP-3 complex subunit beta 1, serine-rich domain [IPR029394]", "AP-3 complex subunit beta, C-terminal domain [IPR029390]", "AP-3 complex subunit delta domain, metazoa [IPR010474]", "AP180 N-terminal homology (ANTH) domain [IPR011417]", "APC10/DOC domain [IPR004939]", "APPL1, BAR domain [IPR037929]", "ARHGEF1-like, PH domain [IPR041020]", "ARHGEF2, PH domain [IPR037806]", "ARID DNA-binding domain [IPR001606]", "ARMET, C-terminal [IPR019345]", "ARMET, N-terminal [IPR045332]", "ATF7-interacting protein , protein binding domain [IPR031870]", "ATP synthase, F1 complex, alpha subunit nucleotide-binding domain [IPR033732]", "ATP synthase, alpha subunit, C-terminal [IPR000793]", "ATP-citrate lyase/succinyl-CoA ligase [IPR005811]", "ATP-citrate synthase, citrate-binding domain [IPR032263]", "ATP-cone domain [IPR005144]", "ATP-dependent DNA helicase RecQ, zinc-binding domain [IPR032284]", "ATP-dependent RNA helicase Ski2, C-terminal [IPR012961]", "ATP-dependent RNA helicase eIF4A, DEAD-box helicase domain [IPR044728]", "ATP-dependent helicase, C-terminal [IPR006555]", "ATP-grasp fold [IPR011761]", "ATP-grasp fold, succinyl-CoA synthetase-type [IPR013650]", "ATP-sulfurylase PUA-like domain [IPR025980]", "ATP:guanido phosphotransferase, N-terminal [IPR022413]", "ATP:guanido phosphotransferase, catalytic domain [IPR022414]", "ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]", "ATPase, AAA-type, core [IPR003959]", "ATPase, BadF/BadG/BcrA/BcrD type [IPR002731]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain [IPR004100]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain [IPR000194]", "ATPase, V1 complex, subunit H, C-terminal [IPR011987]", "ATPase, dynein-related, AAA domain [IPR011704]", "ATPsynthase alpha/beta subunit, N-terminal extension [IPR031686]", "ATRX, ADD domain [IPR041430]", "AWS domain [IPR006560]", "Abscisic acid G-protein coupled receptor-like domain [IPR025969]", "Acetyl-CoA carboxylase [IPR034733]", "Acetyl-CoA carboxylase, central domain [IPR013537]", "Acetyl-coA carboxylase zinc finger domain [IPR041010]", "Acetyl-coenzyme A carboxyltransferase, C-terminal [IPR011763]", "Acetyl-coenzyme A carboxyltransferase, N-terminal [IPR011762]", "Acetyl-coenzyme A synthetase, N-terminal domain [IPR032387]", "Acid ceramidase, N-terminal [IPR029130]", "Acinus, RNA recognition motif [IPR034257]", "Aconitase A, swivel domain [IPR044137]", "Aconitase A/isopropylmalate dehydratase small subunit, swivel domain [IPR000573]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain [IPR001030]", "Actin-depolymerising factor homology domain [IPR002108]", "Activating signal cointegrator 1 complex subunit 2, CUE domain [IPR041800]", "Activator of Hsp90 ATPase, N-terminal [IPR015310]", "Acyl transferase [IPR014043]", "Acyl-CoA dehydrogenase family member 10/11, N-terminal [IPR041726]", "Acyl-CoA dehydrogenase/oxidase C-terminal [IPR009075]", "Acyl-CoA dehydrogenase/oxidase, N-terminal [IPR013786]", "Acyl-CoA oxidase, C-terminal [IPR002655]", "Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091]", "Acyl-CoA-binding protein, ACBP [IPR000582]", "Acyl-coenzyme A oxidase, N-terminal [IPR029320]", "Acylamino-acid-releasing enzyme, N-terminal domain [IPR045550]", "Acylglycerol kinase, C-terminal [IPR045579]", "Acyltransferase, C-terminal domain [IPR032098]", "Adaptor protein Cbl, EF hand-like [IPR014741]", "Adaptor protein Cbl, N-terminal helical [IPR003153]", "Adaptor protein Cbl, PTB domain [IPR024159]", "Adaptor protein Cbl, SH2-like domain [IPR014742]", "Adaptor protein ClpS, core [IPR003769]", "Adenomatous polyposis coli protein basic domain [IPR009234]", "Adenomatous polyposis coli, N-terminal dimerisation domain [IPR032038]", "Adenosine deaminase domain [IPR001365]", "Adenosine deaminase/editase [IPR002466]", "Adenylate cyclase-associated CAP, C-terminal [IPR013912]", "Adenylate cyclase-associated CAP, N-terminal [IPR013992]", "Adenylate kinase, active site lid domain [IPR007862]", "Adenylosuccinate lyase C-terminal [IPR019468]", "Afadin, cargo binding domain [IPR037977]", "Agenet-like domain [IPR008395]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal [IPR007886]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain [IPR007698]", "Alanine racemase, N-terminal [IPR001608]", "Alanyl-tRNA synthetase, class IIc, N-terminal [IPR018164]", "Alanyl-tRNA synthetase, class IIc, core domain [IPR018165]", "Alcohol dehydrogenase, N-terminal [IPR013154]", "Alcohol dehydrogenase-like, C-terminal [IPR013149]", "Aldehyde dehydrogenase domain [IPR015590]", "Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant [IPR000866]", "Alpha Spectrin, SH3 domain [IPR035825]", "Alpha crystallin/Hsp20 domain [IPR002068]", "Alpha galactosidase A, C-terminal beta-sandwich domain [IPR035373]", "Alpha-2-macroglobulin RAP, C-terminal [IPR010483]", "Alpha-2-macroglobulin RAP, domain 2 [IPR038001]", "Alpha-2-macroglobulin RAP, domain 3 [IPR037999]", "Alpha-2-macroglobulin receptor-associated protein, domain 1 [IPR009066]", "Alpha-D-phosphohexomutase, C-terminal [IPR005843]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain I [IPR005844]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain II [IPR005845]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain III [IPR005846]", "Alpha-L-fucosidase, C-terminal [IPR031919]", "Alpha-N-acetylglucosaminidase, C-terminal [IPR024732]", "Alpha-N-acetylglucosaminidase, N-terminal [IPR024240]", "Alpha-N-acetylglucosaminidase, tim-barrel domain [IPR024733]", "Alpha-amylase/branching enzyme, C-terminal all beta [IPR006048]", "Alpha-glycerophosphate oxidase, C-terminal [IPR031656]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like [IPR027450]", "Alpha-ketoglutarate-dependent dioxygenase FTO, C-terminal [IPR024366]", "Alpha-ketoglutarate-dependent dioxygenase FTO, catalytic domain [IPR024367]", "Alpha/beta hydrolase fold-1 [IPR000073]", "Amidase signature domain [IPR023631]", "Amidohydrolase-related [IPR006680]", "Amidophosphoribosyltransferase, N-terminal [IPR035584]", "Amine oxidase [IPR002937]", "Amino acid permease, N-terminal [IPR013612]", "Amino acid permease/ SLC12A domain [IPR004841]", "Amino acid transporter, transmembrane domain [IPR013057]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding [IPR045462]", "Aminoacyl-tRNA synthetase, class II (D/K/N) [IPR004364]", "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) [IPR002314]", "Aminoacyl-tRNA synthetase, class II [IPR006195]", "Aminoacyl-tRNA synthetase, class Ia [IPR002300]", "Aminoglycoside phosphotransferase [IPR002575]", "Aminomethyltransferase, folate-binding domain [IPR006222]", "Aminopeptidase N-like , N-terminal domain [IPR045357]", "Aminopeptidase P [IPR033740]", "Aminopeptidase P, N-terminal [IPR007865]", "Aminotransferase class V domain [IPR000192]", "Aminotransferase, class I/classII [IPR004839]", "Anaphase-promoting complex subunit 1, C-terminal [IPR041221]", "Anaphase-promoting complex subunit 2, C-terminal [IPR014786]", "Anaphase-promoting complex subunit 4, WD40 domain [IPR024977]", "Anaphase-promoting complex subunit 5 domain [IPR026000]", "Ancestral coatomer element 1, Sec16/Sec31 [IPR024298]", "Angiomotin, C-terminal [IPR024646]", "Anillin homology domain [IPR012966]", "Anillin, N-terminal domain [IPR031970]", "Anillin, PH domain [IPR037840]", "Anion-transporting ATPase-like domain [IPR025723]", "Ankyrin repeat and LEM domain-containing protein 2, LEM domain [IPR035006]", "Ankyrin repeat and SOCS box protein 6, SOCS box domain [IPR037327]", "Ankyrin, UPA domain [IPR040745]", "Ankyrin-3, death domain [IPR037971]", "Anticodon-binding [IPR004154]", "Anticodon-binding domain [IPR019181]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal [IPR006190]", "ApaG domain [IPR007474]", "Apoptosis-antagonizing transcription factor, C-terminal [IPR012617]", "Archaeal primase DnaG/twinkle, TOPRIM domain [IPR034154]", "Arf GTPase activating protein [IPR001164]", "Arfaptin homology (AH) domain [IPR010504]", "Arginyl tRNA synthetase N-terminal domain [IPR005148]", "Arginyl-tRNA synthetase, catalytic core domain [IPR035684]", "Ariadne domain [IPR045840]", "Armadillo repeat-containing domain [IPR006911]", "Aromatic amino acid beta-eliminating lyase/threonine aldolase [IPR001597]", "Asn/Gln amidotransferase [IPR018027]", "Asparagine synthase [IPR001962]", "Asparagine synthase, N-terminal domain [IPR033738]", "Aspartate/glutamate/uridylate kinase [IPR001048]", "Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain [IPR006131]", "Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding [IPR006132]", "Aspartic peptidase, DDI1-type [IPR019103]", "Aspartyl beta-hydroxylase/Triadin domain [IPR007943]", "Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic [IPR006075]", "Aspartyl/asparaginy/proline hydroxylase [IPR007803]", "Ataxin 2, SM domain [IPR025852]", "Ataxin-10 domain [IPR019156]", "Ataxin-2, C-terminal [IPR009818]", "Aurora-A binding [IPR015128]", "Autophagy-related, C-terminal [IPR015412]", "B(0)AT2, solute-binding domain [IPR042934]", "B-block binding subunit of TFIIIC [IPR007309]", "B-box, C-terminal [IPR003649]", "B-box-type zinc finger [IPR000315]", "B3/B4 tRNA-binding domain [IPR005146]", "B30.2/SPRY domain [IPR001870]", "BAG domain [IPR003103]", "BAP29/BAP31, transmembrane domain [IPR040463]", "BAR domain [IPR004148]", "BAT2, N-terminal [IPR009738]", "BCL-6 corepressor, PCGF1 binding domain [IPR032365]", "BCL-6 corepressor, non-ankyrin-repeat domain [IPR031628]", "BCNT-C domain [IPR011421]", "BCS1, N-terminal [IPR014851]", "BDHCT [IPR012532]", "BEACH domain [IPR000409]", "BEN domain [IPR018379]", "BING4, C-terminal domain [IPR012952]", "BOP1, N-terminal domain [IPR012953]", "BP28, C-terminal domain [IPR012954]", "BRAP2, RNA recognition motif [IPR034932]", "BRCA1, serine-rich domain [IPR025994]", "BRCA1-associated 2 [IPR011422]", "BRCT domain [IPR001357]", "BRK domain [IPR006576]", "BRO1 domain [IPR004328]", "BSD domain [IPR005607]", "BTB/Kelch-associated [IPR011705]", "BTB/POZ domain [IPR000210]", "BURAN domain [IPR045354]", "BZW1/2, W2 domain [IPR043510]", "Bacterial Ig-like, group 2 [IPR003343]", "Bacterial surface antigen (D15) [IPR000184]", "Band 4.1 domain [IPR019749]", "Band 4.1, C-terminal [IPR008379]", "Band 7 domain [IPR001107]", "Band 7, C-terminal extension [IPR032435]", "Bap31/Bap29 cytoplasmic coiled-coil domain [IPR041672]", "Beta-Casp domain [IPR022712]", "Beta-adaptin appendage, C-terminal subdomain [IPR015151]", "Beta-catenin-interacting ICAT domain [IPR009428]", "Beta-catenin-like protein 1, N-terminal [IPR013180]", "Beta-galactosidase jelly roll domain [IPR025300]", "Beta-hexosaminidase, eukaryotic type, N-terminal [IPR029019]", "Beta-ketoacyl synthase, C-terminal [IPR014031]", "Beta-ketoacyl synthase, N-terminal [IPR014030]", "Beta-lactamase-related [IPR001466]", "Bifunctional delta 1-pyrroline-5-carboxylate synthetase, glutamate-5-kinase domain [IPR041744]", "Biliverdin reductase, catalytic [IPR015249]", "Bin3-type S-adenosyl-L-methionine binding domain [IPR024160]", "Biotin carboxylase, C-terminal [IPR005482]", "Biotin carboxylase-like, N-terminal domain [IPR005481]", "Biotin carboxylation domain [IPR011764]", "Biotin/lipoyl attachment [IPR000089]", "Bloom syndrome protein, BDHCT-box associated domain [IPR032439]", "Bloom syndrome protein, N-terminal domain [IPR032437]", "Bms1/Tsr1-type G domain [IPR030387]", "Borealin, N-terminal [IPR018851]", "Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal [IPR018955]", "Brdt, bromodomain, repeat I [IPR043508]", "Brdt, bromodomain, repeat II [IPR043509]", "Brix domain [IPR007109]", "Bromo adjacent homology (BAH) domain [IPR001025]", "Bromodomain [IPR001487]", "Bromodomain adjacent to zinc finger domain protein 1A, bromodomain [IPR037325]", "Bromodomain protein 4, C-terminal [IPR031354]", "Brr2, N-terminal helicase PWI domain [IPR041094]", "Bud22 domain [IPR015158]", "Butyrophylin-like, SPRY domain [IPR003879]", "C-CAP/cofactor C-like domain [IPR017901]", "C-terminal associated domain of TOPRIM [IPR031660]", "C-type lectin-like [IPR001304]", "C2 DOCK-type domain [IPR027007]", "C2 domain [IPR000008]", "C2 phosphatidylinositol 3-kinase-type domain [IPR002420]", "C2CD5, C2 domain [IPR037785]", "C4-type zinc-finger of DNA polymerase delta [IPR025687]", "CAAX prenyl protease 1, N-terminal [IPR032456]", "CAP Gly-rich domain [IPR000938]", "CAPN2, penta-EF hand, calcium binding motif [IPR042736]", "CARD domain [IPR001315]", "CARG-binding factor, N-terminal [IPR012956]", "CARP motif [IPR006599]", "CASK, SH3 domain [IPR035473]", "CBS domain [IPR000644]", "CCAAT-binding factor [IPR005612]", "CCD97-like, C-terminal [IPR040233]", "CCDC93, coiled-coil domain [IPR019159]", "CCR4-NOT transcription complex subunit 1, CAF1-binding domain [IPR032191]", "CCR4-NOT transcription complex subunit 1, HEAT repeat [IPR032194]", "CCR4-NOT transcription complex subunit 1, TTP binding domain [IPR032193]", "CCR4-NOT transcription complex subunit 1, domain 4 [IPR024557]", "CCR4-Not complex component, Not N-terminal domain [IPR007207]", "CCR4-Not complex component, Not1, C-terminal [IPR007196]", "CD2-associated protein, first SH3 domain [IPR035775]", "CD2-associated protein, second SH3 domain [IPR035776]", "CD2-associated protein, third SH3 domain [IPR035777]", "CD209-like, C-type lectin-like domain [IPR033989]", "CD47 immunoglobulin-like [IPR013270]", "CD47 transmembrane [IPR013147]", "CD80-like, immunoglobulin C2-set [IPR013162]", "CDC48, N-terminal subdomain [IPR003338]", "CDC48, domain 2 [IPR004201]", "CDH1/2, SANT-Helical linker 1 [IPR040793]", "CELF1/2, RNA recognition motif 1 [IPR034196]", "CELF1/2, RNA recognition motif 2 [IPR034198]", "CELF1/2, RNA recognition motif 3 [IPR034199]", "CENP-T/Histone H4, histone fold [IPR035425]", "CENP-V/GFA domain [IPR006913]", "CEP170, C-terminal [IPR029300]", "CFA20 domain [IPR007714]", "CHAT domain [IPR024983]", "CHCH [IPR010625]", "CHD subfamily II, SANT-like domain [IPR009462]", "CHD, C-terminal 2 [IPR012957]", "CHD, N-terminal [IPR012958]", "CHIP, N-terminal tetratricopeptide repeat domain [IPR041312]", "CHIP/LubX , U box domain [IPR045202]", "CHORD domain [IPR007051]", "CID domain [IPR006569]", "CIDE-N domain [IPR003508]", "CLASP N-terminal domain [IPR024395]", "CLU central domain [IPR033646]", "CLU domain [IPR025697]", "CNNM, transmembrane domain [IPR002550]", "COG complex component, COG2, C-terminal [IPR024603]", "COMM domain [IPR017920]", "COMMD1 N-terminal domain [IPR033776]", "COP9 signalosome complex subunit 4, helix turn helix domain [IPR041406]", "COP9 signalosome complex subunit 7, helix I [IPR041481]", "COS domain [IPR017903]", "CP2 transcription factor [IPR007604]", "CPL domain [IPR012959]", "CPPED1, metallophosphatase domain [IPR041867]", "CPSF7, RNA recognition motif [IPR034773]", "CRA domain [IPR013144]", "CRAL-TRIO lipid binding domain [IPR001251]", "CRAL/TRIO, N-terminal domain [IPR011074]", "CRIB domain [IPR000095]", "CRK, C-terminal SH3 domain [IPR035458]", "CRK, N-terminal SH3 domain [IPR035457]", "CS domain [IPR007052]", "CSK-like, SH2 domain [IPR035027]", "CSN8/PSMD8/EIF3K [IPR033464]", "CTLH, C-terminal LisH motif [IPR006595]", "CTLH/CRA C-terminal to LisH motif domain [IPR024964]", "CTP synthase GATase domain [IPR033828]", "CTP synthase, N-terminal [IPR017456]", "CYRIA/CYRIB, Rac1 binding domain [IPR009828]", "Cactin, C-terminal [IPR019134]", "Cactin, central domain [IPR018816]", "Cadherin prodomain [IPR014868]", "Cadherin, cytoplasmic domain [IPR000233]", "Cadherin-like [IPR002126]", "Calcineurin-like phosphoesterase domain, ApaH type [IPR004843]", "Calcineurin-like phosphoesterase domain, lpxH-type [IPR024654]", "Calcium permeable stress-gated cation channel 1, N-terminal transmembrane domain [IPR032880]", "Calcium uniporter protein, C-terminal [IPR006769]", "Calcium-dependent channel, 7TM region, putative phosphate [IPR003864]", "Calcium/calmodulin-dependent protein kinase II, association-domain [IPR013543]", "Calcyclin-binding Protein, CS domain [IPR037893]", "Calpain subdomain III [IPR033883]", "Calponin homology domain [IPR001715]", "Caprin-1 dimerization domain [IPR041637]", "Carbamoyl-phosphate synthase large subunit, CPSase domain [IPR005483]", "Carbamoyl-phosphate synthase small subunit, GATase1 domain [IPR035686]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain [IPR002474]", "Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain [IPR005479]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain [IPR005480]", "Carbohydrate kinase PfkB [IPR011611]", "Carbon-nitrogen hydrolase [IPR003010]", "Carboxylase, conserved domain [IPR003379]", "Carboxypeptidase D, carboxypeptidase-like domain 2 [IPR034224]", "Carboxypeptidase D, carboxypeptidase-like domain 3 [IPR033848]", "Carnitine O-palmitoyltransferase, N-terminal [IPR032476]", "Casein kinase substrate, phosphoprotein PP28 [IPR019380]", "Caspase recruitment domain [IPR031964]", "Cathepsin C [IPR039412]", "Cathepsin C exclusion [IPR014882]", "Cation-transporting P-type ATPase, C-terminal [IPR006068]", "Cation-transporting P-type ATPase, N-terminal [IPR004014]", "Caudal-like activation domain [IPR006820]", "Cdc23 [IPR007192]", "Cdc37, C-terminal [IPR013873]", "Cdc37, Hsp90 binding [IPR013874]", "Cdc37, N-terminal domain [IPR013855]", "Cell division control protein 73, C-terminal [IPR031336]", "Cell morphogenesis central region [IPR029473]", "Cell morphogenesis protein C-terminal [IPR025481]", "Cell morphogenesis protein N-terminal [IPR025614]", "Cellular tumor antigen p53, transactivation domain 2 [IPR040926]", "Centromere protein CENP-B, C-terminal domain [IPR015115]", "Centrosomal CEP44 domain [IPR029157]", "Chaperone DnaJ, C-terminal [IPR002939]", "Checkpoint kinase 1, catalytic domain [IPR034670]", "Chitinase II [IPR011583]", "Choline/carnitine acyltransferase domain [IPR039551]", "Choloylglycine hydrolase/NAAA C-terminal [IPR029132]", "Chromatin assembly factor 1 subunit B, C-terminal domain [IPR029129]", "Chromatin assembly factor 1 subunit p150, C-terminal [IPR029105]", "Chromatin assembly factor 1 subunit p150, N-terminal [IPR029091]", "Chromatin target of PRMT1 protein, C-terminal [IPR025715]", "Chromo domain [IPR023780]", "Chromo domain subgroup [IPR017984]", "Chromo shadow domain [IPR008251]", "Chromo/chromo shadow domain [IPR000953]", "Chromosome passenger complex (CPC) protein INCENP N-terminal [IPR022006]", "Chromosome segregation protein Spc25, C-terminal [IPR013255]", "Circularly permuted (CP)-type guanine nucleotide-binding (G) domain [IPR030378]", "Citron homology (CNH) domain [IPR001180]", "Class I myosin tail homology domain [IPR010926]", "Class I myosin, motor domain [IPR036072]", "Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain [IPR041715]", "Class II PurE [IPR033626]", "Class II aldolase/adducin N-terminal [IPR001303]", "Class VI myosin, motor domain [IPR036114]", "Class XVIII myosin, motor domain [IPR036064]", "Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain [IPR003164]", "Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain [IPR008152]", "Clathrin, heavy chain, linker, core motif [IPR015348]", "Clathrin/coatomer adaptor, adaptin-like, N-terminal [IPR002553]", "Cleavage stimulation factor subunit 1, dimerisation domain [IPR032028]", "Cleavage stimulation factor subunit 2, hinge domain [IPR025742]", "Cleavage/polyadenylation specificity factor, A subunit, C-terminal [IPR004871]", "Cleavage/polyadenylation specificity factor, A subunit, N-terminal [IPR018846]", "Clp ATPase, C-terminal [IPR019489]", "Clustered mitochondria protein, N-terminal [IPR028275]", "Clusterin, C-terminal [IPR016015]", "Clusterin, N-terminal [IPR016014]", "Cns1/TTC4, wheel domain [IPR044059]", "CoA-binding [IPR003781]", "Coatomer beta subunit, C-terminal [IPR011710]", "Coatomer beta subunit, appendage platform domain [IPR029446]", "Coatomer subunit gamma, C-terminal [IPR032154]", "Coatomer, WD associated region [IPR006692]", "Coatomer, alpha subunit, C-terminal [IPR010714]", "Coatomer, gamma subunit, appendage, Ig-like subdomain [IPR013040]", "Cobalamin (vitamin B12)-binding domain [IPR006158]", "Cobalamin (vitamin B12)-binding module, cap domain [IPR003759]", "Cobalamin adenosyltransferase-like [IPR016030]", "Coilin, N-terminal domain [IPR031722]", "Cold shock domain [IPR011129]", "Cold-shock (CSD) domain [IPR019844]", "Cold-shock protein, DNA-binding [IPR002059]", "Complement Clr-like EGF domain [IPR026823]", "Complex 1 LYR protein domain [IPR008011]", "Condensin II complex subunit H2, N-terminal [IPR009378]", "Condensin II complex subunit H2, middle domain [IPR031719]", "Condensin complex subunit 1, C-terminal [IPR032682]", "Condensin complex subunit 1, N-terminal [IPR024324]", "Condensin-2 complex subunit H2, C-terminal [IPR031737]", "Conserved oligomeric Golgi complex, subunit 2, N-terminal [IPR024602]", "Conserved oligomeric Golgi complex, subunit 4 [IPR013167]", "Cop9 signalosome subunit 5 C-terminal domain [IPR040961]", "Copine, C-terminal [IPR010734]", "Copine, C2B domain [IPR037768]", "Core histone macro-H2A, macro domain [IPR035796]", "Cortactin, SH3 domain [IPR035716]", "Cortactin-binding protein-2, N-terminal [IPR019131]", "Creatinase, N-terminal [IPR000587]", "Cro/C1-type helix-turn-helix domain [IPR001387]", "Cullin homology domain [IPR016158]", "Cullin protein, neddylation domain [IPR019559]", "Cullin, N-terminal [IPR001373]", "Cwf19-like protein, C-terminal domain-2 [IPR006767]", "Cwf19-like, C-terminal domain-1 [IPR006768]", "Cyclic nucleotide-binding domain [IPR000595]", "Cyclin, C-terminal domain [IPR004367]", "Cyclin, N-terminal [IPR006671]", "Cyclin-A, N-terminal APC/C binding region [IPR032447]", "Cyclin-dependent kinase 11/PITSLRE, catalytic domain [IPR045267]", "Cyclin-like [IPR013763]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain [IPR002130]", "Cystatin domain [IPR000010]", "Cysteine-rich flanking region, C-terminal [IPR000483]", "Cystine knot, C-terminal [IPR006207]", "Cytidine and deoxycytidylate deaminase domain [IPR002125]", "Cytidyltransferase-like domain [IPR004821]", "Cytochrome C oxidase subunit II, transmembrane domain [IPR011759]", "Cytochrome b-c1 complex subunit Rieske, transmembrane domain [IPR004192]", "Cytochrome b5-like heme/steroid binding domain [IPR001199]", "Cytochrome c oxidase assembly factor 3, mitochondrial, coiled-coil domain [IPR018628]", "Cytochrome c oxidase subunit 2, C-terminal [IPR034210]", "Cytochrome c oxidase subunit II-like C-terminal [IPR002429]", "Cytochrome c oxidase, subunit II [IPR014222]", "Cytoplasmic activation/proliferation-associated protein-1 C term [IPR022070]", "Cytoskeleton-associated protein 2, C-terminal [IPR029197]", "Cytosolic fatty-acid binding [IPR000463]", "D-3-phosphoglycerate dehydrogenase, ASB domain [IPR045626]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain [IPR006140]", "D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain [IPR006139]", "DALR anticodon binding [IPR008909]", "DAMP1, SANT/Myb-like domain [IPR032563]", "DAZ-associated protein 1, RNA recognition motif 1 [IPR034134]", "DAZ-associated protein 1, RNA recognition motif 2 [IPR034131]", "DBC1/CARP1 catalytically inactive NUDIX hydrolase domain [IPR025954]", "DBINO domain [IPR020838]", "DBP10, C-terminal [IPR012541]", "DDE superfamily endonuclease domain [IPR004875]", "DDHD domain [IPR004177]", "DDT domain [IPR018501]", "DDX18/Has1, DEAD-box helicase domain [IPR044773]", "DDX41, DEAD-box helicase domain [IPR044113]", "DDX47/Rrp3, DEAD-box helicase domain [IPR044765]", "DDX52/Rok1, DEAD-box helicase domain [IPR044764]", "DEAD box protein 17, ATP-binding domain [IPR046330]", "DEAD/DEAH box helicase domain [IPR011545]", "DEAD2 [IPR010614]", "DEK, C-terminal [IPR014876]", "DEP domain [IPR000591]", "DET1- and DDB1-associated protein 1, N-terminal [IPR018276]", "DEUBAD domain [IPR044867]", "DExH-box ATP-dependent RNA helicase, R3H domain [IPR034083]", "DFDF domain [IPR025762]", "DHHA1 domain [IPR003156]", "DHX15, DEXH-box helicase domain [IPR044756]", "DHX57, UBA domain [IPR042615]", "DHX8/ Prp22, DEXH-box helicase domain [IPR044762]", "DHX9, DEXH-box helicase domain [IPR044447]", "DHX9, first double-stranded RNA binding domain [IPR044445]", "DHX9, second double-stranded RNA binding domain [IPR044446]", "DIS3-like exonuclease 2, C-terminal [IPR041093]", "DIX domain [IPR001158]", "DJ-1/PfpI [IPR002818]", "DMAP1-binding domain [IPR010506]", "DML1/Misato, tubulin domain [IPR029209]", "DNA (cytosine-5)-methyltransferase 1, replication foci domain [IPR022702]", "DNA binding HTH domain, Psq-type [IPR007889]", "DNA damage inducible protein 1 ubiquitin-like domain [IPR033882]", "DNA fragmentation factor 45kDa, middle domain [IPR015121]", "DNA helicase, DnaB-like, C-terminal [IPR007694]", "DNA ligase 3, BRCT domain [IPR031916]", "DNA ligase, ATP-dependent, C-terminal [IPR012309]", "DNA ligase, ATP-dependent, N-terminal [IPR012308]", "DNA ligase, ATP-dependent, central [IPR012310]", "DNA methyltransferase 1-associated 1 [IPR008468]", "DNA mismatch repair protein MutS, C-terminal [IPR000432]", "DNA mismatch repair protein MutS, clamp [IPR007861]", "DNA mismatch repair protein MutS, connector domain [IPR007860]", "DNA mismatch repair protein MutS, core [IPR007696]", "DNA mismatch repair protein MutS-like, N-terminal [IPR007695]", "DNA mismatch repair protein family, N-terminal [IPR002099]", "DNA mismatch repair protein, S5 domain 2-like [IPR013507]", "DNA polymerase alpha catalytic subunit, N-terminal domain [IPR024647]", "DNA polymerase alpha catalytic subunit, catalytic domain [IPR045846]", "DNA polymerase alpha, subunit B, N-terminal [IPR013627]", "DNA polymerase alpha/delta/epsilon, subunit B [IPR007185]", "DNA polymerase delta subunit 2, C-terminal domain [IPR041863]", "DNA polymerase delta subunit, OB-fold domain [IPR040663]", "DNA polymerase epsilon subunit B, N-terminal [IPR024639]", "DNA polymerase epsilon, catalytic subunit A, C-terminal [IPR013697]", "DNA recombination and repair protein RecA, monomer-monomer interface [IPR020587]", "DNA repair Nbs1, C-terminal [IPR013908]", "DNA replication complex GINS protein SLD5, C-terminal [IPR031633]", "DNA replication factor Dna2, N-terminal [IPR014808]", "DNA replication factor RFC1, C-terminal [IPR013725]", "DNA topoisomerase 2, TOPRIM domain [IPR034157]", "DNA topoisomerase I, DNA binding, eukaryotic-type [IPR008336]", "DNA topoisomerase I, catalytic core, eukaryotic-type [IPR013500]", "DNA topoisomerase I, eukaryotic-type [IPR013499]", "DNA topoisomerase, type IIA, domain A [IPR002205]", "DNA topoisomerase, type IIA, subunit B, domain 2 [IPR013506]", "DNA-dependent protein kinase catalytic subunit, CC3 [IPR012582]", "DNA-dependent protein kinase catalytic subunit, CC5 [IPR045581]", "DNA-dependent protein kinase catalytic subunit, catalytic domain [IPR037706]", "DNA-directed DNA polymerase, family B, exonuclease domain [IPR006133]", "DNA-directed DNA polymerase, family B, multifunctional domain [IPR006134]", "DNA-directed RNA polymerase I subunit RPA2, domain 4 [IPR009674]", "DNA-directed RNA polymerase III subunit RPC1, C-terminal [IPR035698]", "DNA-directed RNA polymerase III subunit RPC1, N-terminal [IPR035697]", "DNA-directed RNA polymerase, N-terminal [IPR029262]", "DNA-directed RNA polymerase, RpoA/D/Rpb3-type [IPR011263]", "DNA-directed RNA polymerase, insert domain [IPR011262]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain [IPR007120]", "DNA-repair protein Xrcc1, N-terminal [IPR002706]", "DNA/RNA non-specific endonuclease [IPR001604]", "DNA/RNA-binding protein Alba-like [IPR002775]", "DNA/RNA-binding protein Kin17, WH-like domain [IPR019447]", "DNA2/NAM7 helicase, helicase domain [IPR041677]", "DNA2/NAM7 helicase-like, C-terminal [IPR041679]", "DOCKER domain [IPR027357]", "DPF1-3, N-terminal domain [IPR025750]", "DSBA-like thioredoxin domain [IPR001853]", "DTHCT [IPR012542]", "DWNN domain [IPR014891]", "DZF domain [IPR006561]", "Damage-control phosphatase ARMT1-like, metal-binding domain [IPR002791]", "Daxx, N-terminal Rassf1C-interacting domain [IPR031333]", "Dbl homology (DH) domain [IPR000219]", "Death domain [IPR000488]", "Dedicator of cytokinesis C, C2 domain [IPR037808]", "Dedicator of cytokinesis C/D, N-terminal [IPR021816]", "Dehydrogenase, E1 component [IPR001017]", "Deoxycytidylate deaminase domain [IPR035105]", "Deoxynucleoside kinase domain [IPR031314]", "Desmoplakin, SH3 domain [IPR041615]", "Desmoplakin, spectrin-like domain [IPR041573]", "Deubiquitinating enzyme MINDY-3/4, conserved domain [IPR025257]", "DhaK domain [IPR004006]", "DhaL domain [IPR004007]", "Diacylglycerol kinase, catalytic domain [IPR001206]", "Diacylglycerol/phorbol-ester binding [IPR020454]", "Diaphanous autoregulatory (DAD) domain [IPR014767]", "Dicer dimerisation domain [IPR005034]", "Dicer, double-stranded RNA-binding domain [IPR044441]", "Dienelactone hydrolase [IPR002925]", "Dihydrofolate reductase domain [IPR001796]", "Dihydroorotate dehydrogenase domain [IPR005720]", "Dilute domain [IPR002710]", "Dip2-like domain [IPR037337]", "Dipeptidyl peptidase 8 /9 ,N-terminal [IPR045785]", "Dipeptidylpeptidase IV, N-terminal domain [IPR002469]", "Dis3-like cold-shock domain 2 [IPR041505]", "Dishevelled C-terminal [IPR024580]", "Dishevelled protein domain [IPR003351]", "Disintegrin domain [IPR001762]", "Disulphide isomerase [IPR005788]", "DnaJ domain [IPR001623]", "DnaJ-like protein C11, C-terminal [IPR024586]", "Dolichyl-phosphate beta-glucosyltransferase [IPR035518]", "Dolichyldiphosphatase, PAP2 domain [IPR039667]", "Domain of unknown function DUF1087 [IPR009463]", "Domain of unknown function DUF1115 [IPR010541]", "Domain of unknown function DUF1605 [IPR011709]", "Domain of unknown function DUF1747 [IPR013719]", "Domain of unknown function DUF1899 [IPR015048]", "Domain of unknown function DUF3350 [IPR021785]", "Domain of unknown function DUF3385, target of rapamycin protein [IPR024585]", "Domain of unknown function DUF3456 [IPR021852]", "Domain of unknown function DUF3480 [IPR022557]", "Domain of unknown function DUF3517 [IPR021905]", "Domain of unknown function DUF3677 [IPR022145]", "Domain of unknown function DUF382 [IPR007180]", "Domain of unknown function DUF4042 [IPR025283]", "Domain of unknown function DUF4149 [IPR025423]", "Domain of unknown function DUF4171 [IPR025228]", "Domain of unknown function DUF4208 [IPR025260]", "Domain of unknown function DUF4217 [IPR025313]", "Domain of unknown function DUF4592 [IPR028030]", "Domain of unknown function DUF4749 [IPR031847]", "Domain of unknown function DUF5050 [IPR032485]", "Domain of unknown function DUF5595 [IPR040967]", "Domain of unknown function DUF5600 [IPR040990]", "Domain of unknown function DUF5921 [IPR045803]", "Domain of unknown function DUF625 [IPR006887]", "Double-stranded RNA-binding domain [IPR014720]", "Down-regulated-in-metastasis protein [IPR011430]", "Drebrin-like protein, SH3 domain [IPR035717]", "Dual specificity phosphatase, catalytic domain [IPR000340]", "Dual specificity protein phosphatase domain [IPR020422]", "Dullard phosphatase domain, eukaryotic [IPR011948]", "Dynamin GTPase effector [IPR003130]", "Dynamin stalk domain [IPR000375]", "Dynamin, GTPase domain [IPR001401]", "Dynamin, N-terminal [IPR045063]", "Dynamin-like GTPase OPA1, C-terminal [IPR045817]", "Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]", "Dynein associated protein [IPR022157]", "Dynein heavy chain AAA lid domain [IPR041658]", "Dynein heavy chain region D6 P-loop domain [IPR004273]", "Dynein heavy chain, AAA 5 extension domain [IPR041466]", "Dynein heavy chain, AAA module D4 [IPR024317]", "Dynein heavy chain, ATP-binding dynein motor region [IPR035706]", "Dynein heavy chain, C-terminal domain [IPR041228]", "Dynein heavy chain, coiled coil stalk [IPR024743]", "Dynein heavy chain, hydrolytic ATP-binding dynein motor region [IPR035699]", "Dynein heavy chain, linker [IPR013602]", "Dynein heavy chain, tail [IPR013594]", "Dyskerin-like [IPR012960]", "E2 binding [IPR014929]", "E3 ligase, CCCH-type zinc finger [IPR041367]", "E3 ubiquitin ligase EDD, ubiquitin-associated domain [IPR024725]", "E3 ubiquitin ligase UBR4, C-terminal [IPR025704]", "E3 ubiquitin ligase, domain of unknown function DUF908 [IPR010309]", "E3 ubiquitin ligase, domain of unknown function DUF913 [IPR010314]", "E3 ubiquitin-protein ligase CBL-B, RING finger, HC subclass [IPR039520]", "E3 ubiquitin-protein ligase RNF220, RING finger [IPR040178]", "E3 ubiquitin-protein ligase RNF220, middle domain [IPR031824]", "E3 ubiquitin-protein ligase UBR-like, C-terminal [IPR044046]", "E3 ubiquitin-protein ligase UBR4, N-terminal [IPR045841]", "EB-1 binding [IPR009232]", "EB1, C-terminal [IPR004953]", "EBP50, C-terminal [IPR015098]", "ECSIT, C-terminal domain [IPR029342]", "EF hand associated, type-1 [IPR013566]", "EF hand associated, type-2 [IPR013567]", "EF-hand domain [IPR002048]", "EF-hand domain, type 1 [IPR015153]", "EF-hand domain, type 2 [IPR015154]", "EF-hand, Ca insensitive [IPR014837]", "EFG, domain V [IPR035649]", "EGF-like calcium-binding domain [IPR001881]", "EGF-like domain [IPR000742]", "EGF-like domain, extracellular [IPR013111]", "EH domain [IPR000261]", "EH domain-containing protein, N-terminal [IPR031692]", "EIF2AK2, first double-stranded RNA binding domain [IPR044452]", "EIF2AK2, second double-stranded RNA binding domain [IPR044453]", "ELK domain [IPR005539]", "ELM2 domain [IPR000949]", "ENTH domain [IPR013809]", "ER membrane protein complex subunit 1, C-terminal [IPR011678]", "ERAP1-like C-terminal domain [IPR024571]", "ERCC3/RAD25/XPB helicase, C-terminal domain [IPR032438]", "ERM family, FERM domain C-lobe [IPR041789]", "ERV/ALR sulfhydryl oxidase domain [IPR017905]", "ERdj5, C-terminal thioredoxin domain [IPR035674]", "ERdj5, first thioredoxin domain [IPR035673]", "ERp29, N-terminal [IPR012883]", "EVE domain [IPR002740]", "EWS, RNA recognition motif [IPR034869]", "EXPERA domain [IPR033118]", "Electron transfer flavoprotein, alpha subunit, C-terminal [IPR014731]", "Electron transfer flavoprotein, alpha subunit, N-terminal [IPR033947]", "Electron transfer flavoprotein, alpha/beta-subunit, N-terminal [IPR014730]", "Electron transfer flavoprotein, beta subunit, N-terminal [IPR033948]", "Elongation Factor G, domain II [IPR041095]", "Elongation factor 1 beta central acidic region, eukaryote [IPR018940]", "Elongation factor 1B gamma, C-terminal [IPR001662]", "Elongation factor EFG, domain V-like [IPR000640]", "Elongation factor G, domain III [IPR009022]", "Elongation factor Tu (EF-Tu), GTP-binding domain [IPR041709]", "Elongation factor Tu, domain 2 [IPR033720]", "Elp3/MiaB/NifB [IPR006638]", "Emerin, LEM domain [IPR034989]", "Endonuclease/exonuclease/phosphatase [IPR005135]", "Endophilin-A, SH3 domain [IPR035824]", "Endophilin-B1, BAR domain [IPR035695]", "Endoplasmic reticulum resident protein 29, C-terminal [IPR011679]", "Endoplasmic reticulum resident protein 44, TRX-like domain b [IPR041870]", "Endoplasmic reticulum resident protein 44, TRX-like domain b' [IPR041862]", "Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]", "Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]", "Enhancer of mRNA-decapping protein 4, WD40 repeat region [IPR032401]", "Enolase, C-terminal TIM barrel domain [IPR020810]", "Enolase, N-terminal [IPR020811]", "Enoyl-CoA hydratase/isomerase domain [IPR045004]", "Era-type guanine nucleotide-binding (G) domain [IPR030388]", "Eukaryotic Ribosomal Protein L27, KOW domain [IPR041991]", "Eukaryotic glycogen debranching enzyme, N-terminal domain [IPR029436]", "Eukaryotic translation initiation factor 3 subunit E, N-terminal [IPR019010]", "Eukaryotic translation initiation factor 3 subunit G, N-terminal [IPR024675]", "Exocyst complex component EXOC2/Sec5, N-terminal domain [IPR039481]", "Exocyst complex component Sec3, C-terminal [IPR019160]", "Exocyst complex component Sec3, PIP2-binding N-terminal domain [IPR028258]", "Exocyst component Exo84, C-terminal [IPR032403]", "Exonuclease 1-like, PIN-like domain [IPR044752]", "Exonuclease, RNase T/DNA polymerase III [IPR013520]", "Exonuclease-1, H3TH domain [IPR037315]", "Exoribonuclease, phosphorolytic domain 1 [IPR001247]", "Exoribonuclease, phosphorolytic domain 2 [IPR015847]", "Exosome complex component CSL4, C-terminal [IPR019495]", "Exosome complex component, N-terminal domain [IPR025721]", "Exosome complex exonuclease RRP44, S1 domain [IPR033770]", "Exosome-associated factor Rrp6, N-terminal [IPR012588]", "Exostosin, GT47 domain [IPR040911]", "Exportin-1, C-terminal [IPR014877]", "Exportin-1/Importin-beta-like [IPR013598]", "Exportin-2, C-terminal [IPR005043]", "Exportin-2, central domain [IPR013713]", "Exportin-5, C-terminal domain [IPR045478]", "Exportin-T, C-terminal domain [IPR045546]", "Extended PHD (ePHD) domain [IPR034732]", "Extended synaptotagmin, C-terminal C2 domain [IPR037752]", "Extended synaptotagmin, C2A domain [IPR037733]", "Extended synaptotagmin, C2B domain [IPR037749]", "Extracellular Endonuclease, subunit A [IPR020821]", "F-BAR domain [IPR031160]", "F-box domain [IPR001810]", "FACT complex subunit POB3-like, N-terminal PH domain [IPR035417]", "FACT complex subunit Spt16 domain [IPR013953]", "FACT complex subunit Spt16, N-terminal lobe domain [IPR029148]", "FACT complex subunit Spt16, peptidase M24-like domain [IPR033825]", "FAD dependent oxidoreductase [IPR006076]", "FAD dependent oxidoreductase, central domain [IPR032503]", "FAD linked oxidase, N-terminal [IPR006094]", "FAD-binding domain, PCMH-type [IPR016166]", "FAD-binding domain, ferredoxin reductase-type [IPR017927]", "FAD-dependent oxidoreductase 2, FAD binding domain [IPR003953]", "FAD-linked oxidase, C-terminal [IPR004113]", "FAD/NAD(P)-binding domain [IPR023753]", "FAF1, UBA-like domain [IPR044541]", "FAM83, N-terminal [IPR012461]", "FANCI helical domain 1 [IPR029310]", "FANCI helical domain 2 [IPR029312]", "FANCI solenoid 1 cap [IPR029305]", "FANCI solenoid 1 domain [IPR029308]", "FANCI solenoid 2 domain [IPR029315]", "FANCI solenoid 3 domain [IPR029313]", "FANCI solenoid 4 domain [IPR029314]", "FAS-associated factor 1-like, UBX domain [IPR033043]", "FAST kinase leucine-rich [IPR010622]", "FAST kinase-like protein, subdomain 2 [IPR013579]", "FATC domain [IPR003152]", "FCH domain [IPR001060]", "FCP1 homology domain [IPR004274]", "FCP1-like phosphatase, C-terminal [IPR015388]", "FCP1-like phosphatase, phosphatase domain [IPR011947]", "FDF domain [IPR019050]", "FERM adjacent (FA) [IPR014847]", "FERM central domain [IPR019748]", "FERM domain [IPR000299]", "FERM, C-terminal PH-like domain [IPR018980]", "FERM, N-terminal [IPR018979]", "FF domain [IPR002713]", "FFD box [IPR025761]", "FGFR1 oncogene partner (FOP), N-terminal dimerisation domain [IPR018993]", "FHF complex subunit HOOK interacting protein, C-terminal [IPR045669]", "FHOD1, N-terminal GTPase-binding domain [IPR041387]", "FIST, C-domain [IPR019494]", "FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]", "FKBP12-rapamycin binding domain [IPR009076]", "FKBP3, basic tilted helix bundle domain [IPR041200]", "FY-rich, C-terminal [IPR003889]", "FY-rich, N-terminal [IPR003888]", "FYVE zinc finger [IPR000306]", "Fanconi anaemia group A protein, N-terminal domain [IPR031729]", "Far upstream element-binding protein, C-terminal [IPR015096]", "Fascin domain [IPR022768]", "Fatty acid hydroxylase [IPR006694]", "Fatty acyl-CoA reductase, C-terminal [IPR033640]", "Fatty acyl-coenzyme A reductase, NAD-binding domain [IPR013120]", "Fcf2 pre-rRNA processing, C-terminal [IPR014810]", "Ferrochelatase, C-terminal [IPR033644]", "Ferrochelatase, N-terminal [IPR033659]", "Fibronectin type II domain [IPR000562]", "Fibronectin type III [IPR003961]", "First polo-box domain [IPR033701]", "Flavodoxin-like [IPR001094]", "Flavodoxin/nitric oxide synthase [IPR008254]", "Flavoprotein pyridine nucleotide cytochrome reductase [IPR001709]", "Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain [IPR008333]", "Follistatin-like, N-terminal [IPR003645]", "Forkhead-associated (FHA) domain [IPR000253]", "Formin, FH2 domain [IPR015425]", "Formin, FH3 domain [IPR010472]", "Formin, GTPase-binding domain [IPR010473]", "Formyl transferase, N-terminal [IPR002376]", "Fragile X-related 1 protein, C-terminal core [IPR022034]", "Fragile X-related 1 protein, C-terminal region 1 [IPR032172]", "Fragile X-related 1 protein, C-terminal region 3 [IPR032177]", "Fragile X-related mental retardation protein, C-terminal region 2 [IPR032196]", "Fumarase C, C-terminal [IPR018951]", "Fumarate lyase, N-terminal [IPR022761]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal [IPR015939]", "Fumarylacetoacetase, N-terminal [IPR015377]", "Fumarylacetoacetase-like, C-terminal [IPR011234]", "Furin-like cysteine-rich domain [IPR006211]", "Fxr1, tudor domain [IPR041560]", "Fzo/mitofusin HR2 domain [IPR006884]", "G-patch domain [IPR000467]", "G-patch domain and KOW motifs-containing protein, KOW 1 [IPR041993]", "G-patch domain and KOW motifs-containing protein, KOW 2 [IPR041994]", "G-protein gamma-like domain [IPR015898]", "G-protein, beta subunit [IPR001632]", "G2 and S phase-expressed protein 1, N-terminal [IPR032768]", "G3BP1, RNA recognition motif [IPR034374]", "G3BP2, RNA recognition motif [IPR034376]", "GAD domain [IPR029351]", "GAR domain [IPR003108]", "GAT domain [IPR004152]", "GB1/RHD3-type guanine nucleotide-binding (G) domain [IPR030386]", "GCC2, Rab binding domain [IPR032023]", "GCF, C-terminal [IPR022783]", "GDAP2, macro domain [IPR035793]", "GHMP kinase N-terminal domain [IPR006204]", "GHMP kinase, C-terminal domain [IPR013750]", "GINS complex protein Sld5, alpha-helical domain [IPR038749]", "GINS subunit, domain A [IPR021151]", "GMP phosphodiesterase, delta subunit [IPR008015]", "GMP synthase, C-terminal [IPR001674]", "GMP synthase, glutamine amidotransferase [IPR004739]", "GMP synthetase ATP pyrophosphatase domain [IPR025777]", "GNAT domain [IPR000182]", "GOLD domain [IPR009038]", "GPAT/DHAPAT, acyltransferase domain [IPR041728]", "GPI ethanolamine phosphate transferase 2, C-terminal [IPR045687]", "GPI ethanolamine phosphate transferase 2, N-terminal [IPR037674]", "GPR domain [IPR000965]", "GRAM domain [IPR004182]", "GRASP-type PDZ domain [IPR024958]", "GRB2, C-terminal SH3 domain [IPR035643]", "GRB2, N-terminal SH3 domain [IPR035641]", "GRIP domain [IPR000237]", "GRSF-1, RNA recognition motif 1 [IPR034425]", "GRSF-1, RNA recognition motif 2 [IPR034424]", "GRSF-1, RNA recognition motif 3 [IPR034426]", "GTP binding domain [IPR006073]", "GTP binding protein 1-like, GTP-binding domain [IPR035531]", "GTP binding protein, second domain [IPR031662]", "GTP-binding protein TrmE, N-terminal [IPR018948]", "GTP1/OBG domain [IPR006169]", "GTPase effector domain [IPR020850]", "GUCT [IPR012562]", "GYF domain [IPR003169]", "Galactokinase, N-terminal domain [IPR019539]", "Galactose mutarotase, N-terminal barrel [IPR031727]", "Galactosyltransferase, C-terminal [IPR027791]", "Galactosyltransferase, N-terminal [IPR027995]", "Gamma tubulin complex component protein, N-terminal [IPR041470]", "Gamma tubulin complex component, C-terminal [IPR040457]", "Gamma-adaptin ear (GAE) domain [IPR008153]", "Gamma-butyrobetaine hydroxylase-like, N-terminal [IPR010376]", "Gamma-glutamyl cyclotransferase-like [IPR013024]", "Gasdermin, PUB domain [IPR041263]", "Gasdermin, pore forming domain [IPR040460]", "Gcp-like domain [IPR000905]", "Gelsolin-like domain [IPR007123]", "Gfo/Idh/MocA-like oxidoreductase, N-terminal [IPR000683]", "Gid-type RING finger domain [IPR044063]", "GlmS/AgaS, SIS domain 1 [IPR035466]", "GlmS/FrlB, SIS domain 2 [IPR035490]", "Glucosamine/galactosamine-6-phosphate isomerase [IPR006148]", "Glucose-6-phosphate dehydrogenase, C-terminal [IPR022675]", "Glucose-6-phosphate dehydrogenase, NAD-binding [IPR022674]", "Glucosidase 2 subunit beta-like [IPR036607]", "Glucosidase II beta subunit, N-terminal [IPR028146]", "Glucosyltransferase 24, catalytic domain [IPR040497]", "Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal [IPR006096]", "Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain [IPR006097]", "Glutaminase, EF-hand domain [IPR041541]", "Glutamine amidotransferase [IPR017926]", "Glutamine amidotransferase type 2 domain [IPR017932]", "Glutamine-Leucine-Glutamine, QLQ [IPR014978]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain 2 [IPR007638]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal [IPR007639]", "Glutamyl-tRNA synthetase [IPR033910]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain [IPR020059]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain [IPR020058]", "Glutaredoxin [IPR002109]", "Glutaredoxin subgroup [IPR014025]", "Glutaredoxin, PICOT-like [IPR033658]", "Glutaredoxin, eukaryotic/virial [IPR011899]", "Glutathione S-transferase, C-terminal [IPR004046]", "Glutathione S-transferase, C-terminal-like [IPR010987]", "Glutathione S-transferase, N-terminal [IPR004045]", "Glutathione S-transferases, class Zeta , C-terminal [IPR034330]", "Glutathione S-transferases, class Zeta , N-terminal [IPR034333]", "Glutathione synthase, substrate-binding domain [IPR004887]", "Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain [IPR020828]", "Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain [IPR020829]", "Glycerol-3-phosphate acyltransferase-like, C-terminal domain [IPR045520]", "Glycerophosphodiester phosphodiesterase domain [IPR030395]", "Glycine cleavage T-protein, C-terminal barrel domain [IPR013977]", "Glycogen debranching enzyme, C-terminal [IPR032790]", "Glycogen debranching enzyme, central domain [IPR032788]", "Glycogen debranching enzyme, glucanotransferase domain [IPR032792]", "Glycogen synthase kinase 3, catalytic domain [IPR039192]", "Glycoside hydrolase 35, catalytic domain [IPR031330]", "Glycoside hydrolase family 18, catalytic domain [IPR001223]", "Glycoside hydrolase family 2, catalytic domain [IPR006103]", "Glycoside hydrolase family 20, catalytic domain [IPR015883]", "Glycoside hydrolase family 31, N-terminal domain [IPR025887]", "Glycoside hydrolase family 38, N-terminal domain [IPR000602]", "Glycoside hydrolase family 38, central domain [IPR015341]", "Glycoside hydrolase, family 13, N-terminal [IPR004193]", "Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich [IPR006102]", "Glycosyl hydrolase family 30, TIM-barrel domain [IPR033453]", "Glycosyl hydrolase family 30, beta sandwich domain [IPR033452]", "Glycosyl hydrolase family 38, C-terminal [IPR011682]", "Glycosyl hydrolase family 63, C-terminal [IPR031335]", "Glycosyl hydrolase family 63, N-terminal [IPR031631]", "Glycosyl hydrolase, family 13, catalytic domain [IPR006047]", "Glycosyl hydrolases family 2, sugar binding domain [IPR006104]", "Glycosyl hydrolases family 38, C-terminal beta sandwich domain [IPR041147]", "Glycosyl transferase 64 domain [IPR015338]", "Glycosyl transferase CAP10 domain [IPR006598]", "Glycosyl transferase, family 1 [IPR001296]", "Glycosyl transferase, family 28, C-terminal [IPR007235]", "Glycosyltransferase 2-like [IPR001173]", "Glycyl-tRNA synthetase-like core domain [IPR033731]", "Glyoxalase domain-containing protein 4, C-terminal [IPR043194]", "Glyoxalase/fosfomycin resistance/dioxygenase domain [IPR004360]", "Golgi pH regulator, conserved domain [IPR022535]", "Golgin subfamily A, conserved domain [IPR043976]", "Growth factor receptor domain 4 [IPR032778]", "Growth hormone-inducible transmembrane protein [IPR035871]", "Guanine nucleotide exchange factor, N-terminal [IPR032691]", "Guanine nucleotide-binding protein-like 3, N-terminal domain [IPR014813]", "Guanylate kinase-like domain [IPR008144]", "Guanylate kinase/L-type calcium channel beta subunit [IPR008145]", "Guanylate-binding protein, N-terminal [IPR015894]", "Guanylate-binding protein/Atlastin, C-terminal [IPR003191]", "HAD-superfamily hydrolase, subfamily IIID [IPR011943]", "HAD-superfamily hydrolase,subfamily IIIA [IPR006549]", "HAUS augmin-like complex subunit 3, N-terminal [IPR032733]", "HAUS augmin-like complex subunit 6, N-terminal [IPR028163]", "HBS1-like protein, N-terminal [IPR015033]", "HD domain [IPR006674]", "HD/PDEase domain [IPR003607]", "HDGF-related, PWWP domain [IPR035496]", "HECT domain [IPR000569]", "HELLS, N-terminal [IPR044753]", "HELP [IPR005108]", "HEPN domain [IPR007842]", "HHH domain 9 [IPR041692]", "HIRAN domain [IPR014905]", "HIT-like domain [IPR011146]", "HOOK, N-terminal [IPR043936]", "HR1 rho-binding domain [IPR011072]", "HRDC domain [IPR002121]", "HSPA4, nucleotide-binding domain [IPR042052]", "HSPA4L, nucleotide-binding domain [IPR042708]", "HSPH1, nucleotide-binding domain [IPR042053]", "HTH CenpB-type DNA-binding domain [IPR006600]", "HTTM [IPR011020]", "HUWE1, UBA domain [IPR041918]", "Heat shock 70kDa protein 14, nucleotide-binding domain [IPR042049]", "Heat shock chaperonin-binding [IPR006636]", "Heat shock protein DnaJ, cysteine-rich domain [IPR001305]", "Heat shock protein Hsp90, N-terminal [IPR020575]", "Heat shock protein beta-1, ACD domain [IPR037876]", "Helical and beta-bridge domain [IPR010643]", "Helicase XPB/Ssl2, N-terminal domain [IPR032830]", "Helicase domain [IPR007807]", "Helicase superfamily 1/2, ATP-binding domain [IPR014001]", "Helicase superfamily 1/2, ATP-binding domain, DinG/Rad3-type [IPR014013]", "Helicase, C-terminal [IPR001650]", "Helicase-associated domain [IPR007502]", "Helicase-like, DEXD box c2 type [IPR006554]", "Helicase/SANT-associated domain [IPR014012]", "Helicase/UvrB, N-terminal [IPR006935]", "Helix-hairpin-helix DNA-binding motif, class 1 [IPR003583]", "Helix-turn-helix DNA-binding domain of Spt6 [IPR028088]", "Hemimethylated DNA-binding domain [IPR011722]", "Hepatitis delta antigen (HDAg) domain [IPR037517]", "Hepatocyte growth factor-regulated tyrosine kinase substrate, helical domain [IPR024641]", "Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 1 [IPR034544]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 2 [IPR034548]", "Heterogeneous nuclear ribonucleoprotein R, RNA recognition motif 2 [IPR034411]", "Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778]", "Hexokinase, C-terminal [IPR022673]", "Hexokinase, N-terminal [IPR022672]", "High mobility group box domain 5 [IPR029215]", "High mobility group box domain [IPR009071]", "Histidine kinase domain [IPR005467]", "Histidine kinase/HSP90-like ATPase [IPR003594]", "Histidyl tRNA synthetase-related domain [IPR024435]", "Histidyl-anticodon-binding [IPR033656]", "Histone H2A, C-terminal domain [IPR032454]", "Histone H2A/H2B/H3 [IPR007125]", "Histone acetyl transferase HAT1 N-terminal [IPR019467]", "Histone acetyltransferase domain, MYST-type [IPR002717]", "Histone chaperone domain CHZ [IPR019098]", "Histone deacetylase complex subunit SAP130, C-terminal domain [IPR031963]", "Histone deacetylase domain [IPR023801]", "Histone deacetylase interacting domain [IPR013194]", "Histone-arginine methyltransferase CARM1, N-terminal [IPR020989]", "Histone-binding protein RBBP4, N-terminal [IPR022052]", "HnRNP M, nuclear localisation signal [IPR024666]", "Homeobox domain [IPR001356]", "Homeobox domain, metazoa [IPR020479]", "Homeobox protein Hox1A3 N-terminal [IPR022067]", "Homocysteine-binding domain [IPR003726]", "Hotdog acyl-CoA thioesterase (ACOT)-type domain [IPR033120]", "HuR, RNA recognition motif 2 [IPR034996]", "Huntingtin-interacting protein 1, clathrin-binding domain [IPR032422]", "Hyaluronan-mediated motility receptor, C-terminal [IPR031794]", "Hyaluronan/mRNA-binding protein [IPR006861]", "Hydroxyacylglutathione hydrolase, C-terminal domain [IPR032282]", "Hydroxyacylglutathione hydrolase, MBL domain [IPR035680]", "Hydroxymethylglutaryl-coenzyme A synthase, C-terminal domain [IPR013746]", "Hydroxymethylglutaryl-coenzyme A synthase, N-terminal [IPR013528]", "I-kappa-kinase-beta NEMO binding domain [IPR022007]", "I/LWEQ domain [IPR002558]", "IBR domain [IPR002867]", "IF2a, S1-like domain [IPR044126]", "IGF2BP1, RNA recognition motif 1 [IPR034837]", "IGF2BP1, RNA recognition motif 2 [IPR034842]", "IGF2BP2, RNA recognition motif 1 [IPR034843]", "IGF2BP3, RNA recognition motif 2 [IPR034844]", "IKBKB, scaffold dimerization domain [IPR041185]", "IMD/I-BAR domain [IPR013606]", "IMP dehydrogenase/GMP reductase [IPR001093]", "IPS1, CARD domain [IPR042144]", "IPT domain [IPR002909]", "IRG-type guanine nucleotide-binding (G) domain [IPR030385]", "IRS-type PTB domain [IPR002404]", "IRSp53, SH3 domain [IPR035594]", "ISG20, DEDDh 3'-5' exonuclease domain [IPR037433]", "ISWI, HAND domain [IPR015194]", "Ima1, N-terminal domain [IPR018617]", "Immunoglobulin C1-set [IPR003597]", "Immunoglobulin I-set [IPR013098]", "Immunoglobulin V-set domain [IPR013106]", "Immunoglobulin subtype 2 [IPR003598]", "Immunoglobulin subtype [IPR003599]", "Immunoglobulin-like domain [IPR007110]", "Importin-alpha, importin-beta-binding domain [IPR002652]", "Importin-beta, N-terminal domain [IPR001494]", "Initiation factor eIF-4 gamma, MA3 [IPR003891]", "Inner centromere protein, ARK-binding domain [IPR005635]", "Inositol polyphosphate 5-phosphatase, clathrin binding domain [IPR031995]", "Inositol polyphosphate-related phosphatase [IPR000300]", "Int12, PHD finger [IPR039054]", "Integrator complex subunit 11, MBL-fold [IPR041897]", "Integrator complex subunit 14, C-terminal [IPR045814]", "Integrator complex subunit 3, N-terminal [IPR019333]", "Integrin beta N-terminal [IPR033760]", "Integrin beta subunit, VWA domain [IPR002369]", "Integrin beta subunit, cytoplasmic domain [IPR014836]", "Integrin beta subunit, tail [IPR012896]", "Integrin beta, epidermal growth factor-like domain 1 [IPR040622]", "Integrin-linked protein kinase, pseudokinase domain [IPR035692]", "Interferon gamma receptor, poxvirus/mammal [IPR021126]", "Interferon regulatory factor 2-binding protein 1 & 2, zinc finger [IPR022750]", "Intermediate filament head, DNA-binding domain [IPR006821]", "Intermediate filament, rod domain [IPR039008]", "Intersectin-2, fifth SH3 domain [IPR035741]", "Intersectin-2, first SH3 domain [IPR035737]", "Intersectin-2, fourth SH3 domain [IPR035740]", "Intersectin-2, second SH3 domain [IPR035738]", "Intersectin-2, third SH3 domain [IPR035739]", "Intracellular hyaluronan-binding protein 4, N-terminal domain [IPR032381]", "Intron-binding protein aquarius, N-terminal [IPR032174]", "Ion transporter-like, CBS domain [IPR044751]", "Iron sulphur domain-containing, mitoNEET, N-terminal [IPR019610]", "Iron-binding zinc finger, CDGSH type [IPR018967]", "Isochorismatase-like [IPR000868]", "Isoleucyl tRNA synthetase type 1, anticodon-binding domain [IPR033708]", "Isoleucyl tRNA synthetase type 2, anticodon-binding domain [IPR033709]", "Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain [IPR044861]", "Isopropylmalate dehydrogenase-like domain [IPR024084]", "JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]", "JNK-interacting protein, leucine zipper II [IPR032486]", "JNK/Rab-associated protein-1, N-terminal [IPR019143]", "JmjC domain [IPR003347]", "Jumonji, helical domain [IPR041070]", "K Homology domain [IPR004087]", "K Homology domain, type 1 [IPR004088]", "K Homology domain, type 2 [IPR004044]", "KASH domain [IPR012315]", "KELK-motif containing domain [IPR031597]", "KHDRBS, Qua1 domain [IPR032571]", "KMT2A, PHD domain 1 [IPR042023]", "KMT2A, PHD domain 2 [IPR042025]", "KMT2A, PHD domain 3 [IPR044133]", "KMT2A, ePHD domain [IPR041958]", "KN17, SH3-like C-terminal domain [IPR041330]", "KOW [IPR005824]", "Kin17, KOW domain [IPR041995]", "Kinase associated domain 1 (KA1) [IPR001772]", "Kindlin-2, N-terminal [IPR040790]", "Kindlin/fermitin, PH domain [IPR037837]", "Kinesin motor domain [IPR001752]", "Kinesin-associated [IPR032405]", "Kinesin-associated microtubule-binding domain [IPR025901]", "Kinesin-like KIF1-type [IPR022140]", "Kinesin-like [IPR022164]", "Kinesin-like protein Kif23, Arf6-interacting domain [IPR032384]", "Kinetochore protein Nuf2, N-terminal [IPR005549]", "Kri1-like, C-terminal [IPR024626]", "Krr1, KH1 domain [IPR041174]", "Ku, C-terminal [IPR014893]", "Ku70/Ku80 C-terminal arm [IPR005160]", "Ku70/Ku80 beta-barrel domain [IPR006164]", "Ku70/Ku80, N-terminal alpha/beta [IPR005161]", "L27 domain [IPR004172]", "L27 domain, C-terminal [IPR014775]", "LAIKA domain [IPR045353]", "LARP4, RNA recognition motif [IPR034903]", "LARP5, RNA recognition motif [IPR034900]", "LARP7, RNA recognition motif 1 [IPR034887]", "LARP7, RNA recognition motif 2 [IPR034910]", "LEM domain [IPR003887]", "LEM-like domain [IPR013146]", "LETM1, ribosome-binding domain [IPR033122]", "LETM1-like [IPR011685]", "LIS1 homology motif [IPR006594]", "LSM domain, eukaryotic/archaea-type [IPR001163]", "LSM-interacting domain [IPR008669]", "La protein, xRRM domain [IPR014886]", "La-related protein 7, La domain [IPR034946]", "La-type HTH domain [IPR006630]", "Lactate/malate dehydrogenase, C-terminal [IPR022383]", "Lactate/malate dehydrogenase, N-terminal [IPR001236]", "Lamin tail domain [IPR001322]", "Lamin-B receptor of TUDOR domain [IPR019023]", "Lamina-associated polypeptide 2 alpha, C-terminal [IPR021623]", "Laminin G domain [IPR001791]", "Laminin IV [IPR000034]", "Laminin IV type B [IPR013015]", "Laminin, N-terminal [IPR008211]", "Laminin-type EGF domain [IPR002049]", "Large proline-rich protein BAG6 [IPR021925]", "Lasp1, SH3 domain [IPR035630]", "Legume-like lectin [IPR005052]", "Lens epithelium-derived growth factor, integrase-binding domain [IPR021567]", "Lethal giant larvae homologue 2 [IPR013577]", "Leucine zipper, homeobox-associated [IPR003106]", "Leucine-rich repeat N-terminal domain [IPR000372]", "Leukocyte surface antigen CD47, IgV [IPR037805]", "Linker histone H1/H5, domain H15 [IPR005818]", "Lipocalin/cytosolic fatty-acid binding domain [IPR000566]", "Liprin-alpha, SAM domain repeat 1 [IPR037620]", "Liprin-alpha, SAM domain repeat 2 [IPR037621]", "Liprin-alpha, SAM domain repeat 3 [IPR037622]", "Listerin, zinc finger, RING-type [IPR039804]", "Lon, substrate-binding domain [IPR003111]", "Longin domain [IPR010908]", "Lsm14-like, N-terminal [IPR025609]", "Lsm16, N-terminal [IPR034107]", "LsmAD domain [IPR009604]", "Lysine-tRNA ligase, class II, N-terminal [IPR044136]", "Lysophosphatidylcholine acyltransferase LPCAT1-like [IPR045252]", "Lysyl-tRNA synthetase, class II, C-terminal [IPR018149]", "M60-like domain, N-terminal [IPR035423]", "MABP domain [IPR023341]", "MAGE homology domain [IPR002190]", "MAN1, RNA recognition motif [IPR034394]", "MANSC domain [IPR013980]", "MATH/TRAF domain [IPR002083]", "MCM N-terminal domain [IPR027925]", "MCM OB domain [IPR033762]", "MCM domain [IPR001208]", "MCM, AAA-lid domain [IPR041562]", "MD-2-related lipid-recognition domain [IPR003172]", "MDM2-binding protein, N-terminal domain [IPR029421]", "MDM2-binding protein, central domain [IPR029420]", "MDN2-binding protein, C-terminal domain [IPR029418]", "MEF-2, RNA recognition motif 1 [IPR034630]", "MEF-2, RNA recognition motif 3 [IPR034631]", "MENTAL domain [IPR019498]", "MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]", "MHC class I, alpha chain, C-terminal [IPR010579]", "MHC class I-like antigen recognition-like [IPR011161]", "MIA2, SH3 domain [IPR035555]", "MIF4G-like, type 1 [IPR015172]", "MIF4G-like, type 2 [IPR015174]", "MIF4G-like, type 3 [IPR003890]", "MIR motif [IPR016093]", "MIRO domain [IPR020860]", "MIT domain [IPR007330]", "MKI67 FHA domain-interacting nucleolar phosphoprotein, FHA Ki67 binding [IPR021043]", "MMS19, C-terminal [IPR024687]", "MMS19, N-terminal [IPR029240]", "MOSC, N-terminal beta barrel [IPR005303]", "MPN domain [IPR037518]", "MPP1, SH3 domain [IPR035475]", "MPP2, SH3 domain [IPR035602]", "MPP6, SH3 domain [IPR035603]", "MPP7, SH3 domain [IPR035599]", "MRG domain [IPR026541]", "MRH domain [IPR044865]", "MRPL44, double-stranded RNA binding domain [IPR044444]", "MST4, kinase domain [IPR035056]", "MYND-like zinc finger [IPR031615]", "MYST, zinc finger domain [IPR040706]", "Macro domain [IPR002589]", "Mad3/Bub1 homology region 1 [IPR013212]", "Major facilitator superfamily domain [IPR020846]", "Major sperm protein (MSP) domain [IPR000535]", "Malectin domain [IPR021720]", "Malic enzyme, N-terminal domain [IPR012301]", "Malic enzyme, NAD-binding [IPR012302]", "Man1/Src1, C-terminal [IPR018996]", "Manganese/iron superoxide dismutase, C-terminal [IPR019832]", "Manganese/iron superoxide dismutase, N-terminal [IPR019831]", "Mannose-1-phosphate guanyltransferase, N-terminal domain [IPR045233]", "MaoC-like dehydratase domain [IPR002539]", "Marvel domain [IPR008253]", "Matrin-3, RNA recognition motif 1 [IPR034928]", "Matrin-3, RNA recognition motif 2 [IPR034930]", "Matrin/U1-C, C2H2-type zinc finger [IPR000690]", "Matrin/U1-C-like, C2H2-type zinc finger [IPR003604]", "Mcm6, C-terminal winged-helix domain [IPR041024]", "Mediator complex, subunit Med1 [IPR019680]", "Membrane insertase YidC/Oxa1, C-terminal [IPR028055]", "Metallo-beta-lactamase [IPR001279]", "Metastasis-associated protein MTA1, R1 domain [IPR035170]", "Metaxin, glutathione S-transferase domain [IPR033468]", "Methionine synthase, B12-binding domain [IPR033706]", "Methionine--tRNA ligase, N-terminal [IPR041598]", "Methioninyl-tRNA synthetase core domain [IPR033911]", "Methionyl-tRNA synthetase, anticodon-binding domain [IPR041872]", "Methionyl/Leucyl tRNA synthetase [IPR015413]", "Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding [IPR013155]", "Methyl-CpG DNA binding [IPR001739]", "Methylglyoxal synthase-like domain [IPR011607]", "Methylmalonyl-CoA mutase, C-terminal [IPR006159]", "Methylmalonyl-CoA mutase, alpha chain, catalytic [IPR006098]", "Methylmalonyl-CoA mutase, alpha/beta chain, catalytic [IPR006099]", "Methylthiotransferase, N-terminal [IPR013848]", "Methyltransferase domain 25 [IPR041698]", "Methyltransferase domain [IPR025714]", "Methyltransferase type 11 [IPR013216]", "Methyltransferase type 12 [IPR013217]", "Mff-like domain [IPR039433]", "Mib-herc2 [IPR010606]", "Micro-fibrillar-associated protein 1, C-terminal [IPR009730]", "Midasin AAA lid domain 5 [IPR041190]", "Midasin, AAA lid domain 7 [IPR040848]", "Midline-1, COS domain [IPR040859]", "Minichromosome loss protein Mcl1, middle region [IPR022100]", "Misato Segment II tubulin-like domain [IPR019605]", "Mitochondria fission protein Fis1, cytosolic domain [IPR033745]", "Mitochondrial apoptosis-inducing factor, C-terminal domain [IPR029324]", "Mitochondrial cytochrome c oxidase subunit VIc/VIIs [IPR034884]", "Mitochondrial degradasome RNA helicase subunit, C-terminal domain [IPR022192]", "Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564]", "Mitochondrial ribosomal protein L46 NUDIX [IPR033650]", "MnmE, helical domain [IPR025867]", "MoaB/Mog domain [IPR001453]", "Modifier of rudimentary, Modr [IPR009851]", "MoeA, C-terminal, domain IV [IPR005111]", "MoeA, N-terminal and linker domain [IPR005110]", "Molybdenum cofactor sulfurase, C-terminal [IPR005302]", "Molybdopterin oxidoreductase [IPR006656]", "Molybdopterin oxidoreductase, 4Fe-4S domain [IPR006963]", "Morc, S5 domain 2-like [IPR041006]", "Mre11 nuclease, N-terminal metallophosphatase domain [IPR041796]", "Mre11, DNA-binding [IPR007281]", "Mst1 SARAH domain [IPR024205]", "Mu homology domain [IPR028565]", "Mu2, C-terminal domain [IPR043512]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal [IPR031717]", "Multiple myeloma tumor-associated protein 2-like, N-terminal [IPR019315]", "Multiprotein bridging factor 1, N-terminal [IPR013729]", "Muskelin, N-terminal [IPR010565]", "Myb domain [IPR017930]", "Myc-type, basic helix-loop-helix (bHLH) domain [IPR011598]", "Myo-inositol-1-phosphate synthase, GAPDH-like [IPR013021]", "Myosin VI, cargo binding domain [IPR032412]", "Myosin head, motor domain [IPR001609]", "Myosin phosphatase-RhoA interacting protein, PH domain [IPR039597]", "Myosin tail [IPR002928]", "Myosin, N-terminal, SH3-like [IPR004009]", "Myosin-binding domain [IPR026859]", "Myotonic dystrophy protein kinase, coiled coil [IPR014930]", "Myotubularin-like phosphatase domain [IPR010569]", "Myristoyl-CoA:protein N-myristoyltransferase, C-terminal [IPR022677]", "Myristoyl-CoA:protein N-myristoyltransferase, N-terminal [IPR022676]", "N-CoR, GPS2-interacting domain [IPR031557]", "N-acetylgalactosaminyltransferase [IPR045885]", "N-acetylneuraminic acid synthase, N-terminal [IPR013132]", "N-end aminoacyl transferase, N-terminal [IPR007471]", "N-end rule aminoacyl transferase, C-terminal [IPR007472]", "N-terminal extension of GAT domain [IPR041198]", "NAD(P) binding domain of glutamate dehydrogenase [IPR033922]", "NAD(P) transhydrogenase, alpha subunit, C-terminal [IPR024605]", "NAD(P)-binding domain [IPR016040]", "NAD-dependent epimerase/dehydratase [IPR001509]", "NAD/GMP synthase [IPR022310]", "NADH dehydrogenase subunit 5, C-terminal [IPR010934]", "NADH pyrophosphatase-like, N-terminal [IPR015375]", "NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal [IPR001516]", "NADH-quinone oxidoreductase, chain G, C-terminal [IPR015405]", "NADH-quinone oxidoreductase, subunit D [IPR001135]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain [IPR011538]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain [IPR019575]", "NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit [IPR001750]", "NADH:ubiquinone oxidoreductase, 30kDa subunit [IPR001268]", "NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding [IPR019574]", "NADH:ubiquinone oxidoreductase-like, 20kDa subunit [IPR006137]", "NADP transhydrogenase beta-like domain [IPR034300]", "NADP-dependent oxidoreductase domain [IPR023210]", "NDUFA6, LYR domain [IPR045299]", "NDUFB9, LYR domain [IPR045292]", "NECAP, PHear domain [IPR012466]", "NEDD8 ultimate buster 1, ubiquitin-like domain [IPR041207]", "NEMO, Zinc finger [IPR034735]", "NET domain [IPR027353]", "NF-kappa-B essential modulator NEMO, CC2-LZ domain [IPR032419]", "NF-kappa-B essential modulator NEMO, N-terminal [IPR021063]", "NF-kappaB-repression factor, R3H domain [IPR034071]", "NFACT protein, C-terminal [IPR021846]", "NFACT, RNA-binding domain [IPR008532]", "NFkappaB IPT domain [IPR033926]", "NGN domain [IPR005100]", "NGN domain, eukaryotic [IPR039385]", "NHL2, NHL repeat domain [IPR045302]", "NIF system FeS cluster assembly, NifU, C-terminal [IPR001075]", "NIF system FeS cluster assembly, NifU, N-terminal [IPR002871]", "NIPSNAP [IPR012577]", "NLE [IPR012972]", "NOG, C-terminal [IPR012973]", "NOG1, N-terminal helical domain [IPR041623]", "NOP5, N-terminal [IPR012974]", "NOPS [IPR012975]", "NOSIC [IPR012976]", "NOT2/NOT3/NOT5, C-terminal [IPR007282]", "NP60, PWWP domain [IPR035501]", "NPL4, zinc-binding putative [IPR007716]", "NSD, Cys-His rich domain [IPR041306]", "NT-type C2 domain [IPR019448]", "NUC153 [IPR012580]", "NUC205 domain [IPR012584]", "NUDIX hydrolase [IPR020476]", "NUDIX hydrolase domain [IPR000086]", "NVL2, nucleolin binding domain [IPR031996]", "Nascent polypeptide-associated complex NAC domain [IPR002715]", "Negative elongation factor E, RNA recognition motif [IPR034637]", "Neurexin/syndecan/glycophorin C [IPR003585]", "Neurobeachin-like, DUF1088 [IPR010508]", "Neurobeachin/BDCP, DUF4704 [IPR031570]", "Neuroblastoma-amplified sequence, N-terminal [IPR029145]", "Nibrin, second BRCT domain [IPR032429]", "Nicastrin, small lobe [IPR041084]", "Nicotinamide phosphoribosyltransferase, N-terminal domain [IPR041529]", "Nicotinate/nicotinamide phosphoribosyltransferase [IPR041525]", "Niemann-Pick C1, N-terminal [IPR032190]", "Nin one binding (NOB1) Zn-ribbon-like [IPR014881]", "Nischarin, PX domain [IPR037904]", "Nit1/2, carbon-nitrogen hydrolase domain [IPR045254]", "Nitric oxide synthase-interacting protein, zinc-finger [IPR031790]", "Nmd3, N-terminal [IPR007064]", "Non-canonical purine NTP phosphatase/PRRC1 [IPR026533]", "Nop domain [IPR002687]", "Nop2p [IPR011023]", "Novel protein kinase C delta, catalytic domain [IPR034667]", "Npc2 like, ML domain [IPR033916]", "Nrap protein domain 1 [IPR035082]", "Nrap protein, domain 2 [IPR035367]", "Nrap protein, domain 3 [IPR035368]", "Nrap protein, domain 4 [IPR035369]", "Nrap protein, domain 5 [IPR035370]", "Nrap protein, domain 6 [IPR035371]", "Nuclear RNA export factor Tap, RNA-binding domain [IPR015245]", "Nuclear condensin complex subunit 3, C-terminal domain [IPR025977]", "Nuclear migration protein nudC [IPR032572]", "Nuclear pore complex protein Nup214, phenylalanine-glycine (FG) domain [IPR041553]", "Nuclear pore complex, NUP2/50/61 [IPR015007]", "Nuclear pore localisation protein NPL4, C-terminal [IPR007717]", "Nuclear pore localisation protein Npl4, ubiquitin-like domain [IPR024682]", "Nuclear protein 96 [IPR021967]", "Nuclear transport factor 2 domain [IPR002075]", "Nuclear transport factor 2, eukaryote [IPR018222]", "Nuclear-interacting partner of ALK/Rsm1-like [IPR013909]", "Nucleolar GTP-binding protein 1, Rossman-fold domain [IPR010674]", "Nucleolar GTP-binding protein 2, N-terminal domain [IPR012971]", "Nucleolar complex-associated protein 3, N-terminal [IPR011501]", "Nucleolar pre-ribosomal-associated protein 1, C-terminal domain [IPR032436]", "Nucleolar pre-ribosomal-associated protein 1, N-terminal [IPR021714]", "Nucleolar protein 7, C-terminal [IPR012579]", "Nucleolar protein 8, RNA recognition motif [IPR034138]", "Nucleolin, RNA recognition motif 1 [IPR034230]", "Nucleolin, RNA recognition motif 2 [IPR034233]", "Nucleolin, RNA recognition motif 3 [IPR034234]", "Nucleolin, RNA recognition motif 4 [IPR034235]", "Nucleophosmin, C-terminal [IPR032569]", "Nucleoplasmin core domain [IPR024057]", "Nucleoporin Nup153, N-terminal [IPR013913]", "Nucleoporin Nup188, N-terminal [IPR018864]", "Nucleoporin Nup54, alpha-helical domain [IPR025712]", "Nucleoporin, NSP1-like, C-terminal [IPR007758]", "Nucleoporin, Nup133/Nup155-like, C-terminal [IPR007187]", "Nucleoporin, Nup133/Nup155-like, N-terminal [IPR014908]", "Nucleoprotein TPR/MLP1 [IPR012929]", "Nucleoredoxin, redox inactive TRX-like domain b' [IPR041861]", "Nucleoside diphosphate kinase-like domain [IPR034907]", "Nucleoside phosphorylase domain [IPR000845]", "Nucleotide exchange factor Fes1 [IPR013918]", "Nucleotidyl transferase domain [IPR005835]", "NudC N-terminal domain [IPR025934]", "NudC domain-containing protein 2, p23 domain [IPR037902]", "NudC domain-containing protein 3, p23 domain [IPR037905]", "NuoE domain [IPR042128]", "Nup358/RanBP2 E3 ligase domain [IPR022011]", "Nup54, C-terminal interacting domain [IPR040985]", "NusG, N-terminal [IPR006645]", "O-GlcNAc transferase, C-terminal [IPR029489]", "OB-fold nucleic acid binding domain, AA-tRNA synthetase-type [IPR004365]", "OBG-type guanine nucleotide-binding (G) domain [IPR031167]", "OCRE domain [IPR041591]", "OCRL1, PH domain [IPR037787]", "OCRL1/INPP5B, INPP5c domain [IPR037793]", "OST-HTH/LOTUS domain [IPR025605]", "OTU domain [IPR003323]", "Occludin homology domain [IPR010844]", "Orc1-like, AAA ATPase domain [IPR041664]", "Origin recognition complex subunit 3, N-terminal [IPR045667]", "Origin recognition complex subunit 3, insertion domain [IPR045663]", "Origin recognition complex subunit 3, winged helix C-terminal [IPR040855]", "Orotate phosphoribosyl transferase domain [IPR004467]", "Orotidine 5'-phosphate decarboxylase domain [IPR001754]", "Ovarian carcinoma immunoreactive antigen domain [IPR009764]", "Oxidoreductase FAD/NAD(P)-binding [IPR001433]", "Oxidoreductase, N-terminal domain [IPR041694]", "Oxoglutarate/iron-dependent dioxygenase [IPR005123]", "P-type ATPase, haloacid dehalogenase domain [IPR044492]", "P-type trefoil domain [IPR000519]", "PA domain [IPR003137]", "PABP, RNA recognition motif 2 [IPR045305]", "PACSIN1/PACSIN2, SH3 domain [IPR035743]", "PACSIN2, F-BAR domain [IPR037453]", "PADR1 domain [IPR012982]", "PAP/25A-associated [IPR002058]", "PARN, R3H domain [IPR034042]", "PAZ domain [IPR003100]", "PB1 domain [IPR000270]", "PD-(D/E)XK endonuclease-like domain, AddAB-type [IPR038726]", "PDIP3, RNA recognition motif [IPR034784]", "PDZ domain 6 [IPR041489]", "PDZ domain [IPR001478]", "PET domain [IPR010442]", "PET testin [IPR033724]", "PH-BEACH domain [IPR023362]", "PHR [IPR012983]", "PI31 proteasome regulator, N-terminal [IPR021625]", "PI31 proteasome regulator, C-terminal [IPR013886]", "PI3K-C2-alpha, catalytic domain [IPR037705]", "PI4-kinase, N-terminal [IPR045495]", "PIH1, N-terminal [IPR012981]", "PIH1D1/2/3, CS-like domain [IPR041442]", "PIK-related kinase [IPR014009]", "PIK-related kinase, FAT [IPR003151]", "PIN domain [IPR002716]", "PITH domain [IPR010400]", "PKD domain [IPR000601]", "PKD/Chitinase domain [IPR022409]", "PLAA family ubiquitin binding domain [IPR015155]", "PLC-beta, PH domain [IPR037862]", "PLC-gamma, C-terminal SH2 domain [IPR035023]", "PLC-gamma, N-terminal SH2 domain [IPR035024]", "PLD-like domain [IPR032803]", "PNK, FHA domain [IPR041388]", "POLO box domain [IPR000959]", "POPLD domain [IPR012590]", "POTRA domain [IPR034746]", "PP2B, metallophosphatase domain [IPR041751]", "PP5, C-terminal metallophosphatase domain [IPR041753]", "PPIL4-like, cyclophilin domain [IPR035538]", "PPM-type phosphatase domain [IPR001932]", "PPP domain [IPR013235]", "PRKAA1, UBA-like autoinhibitory domain [IPR028797]", "PRKAA2, UBA-like autoinhibitory domain [IPR028783]", "PRKCBP1, PHD finger [IPR044075]", "PRMT5 arginine-N-methyltransferase [IPR035075]", "PRMT5, TIM barrel domain [IPR035247]", "PRMT5, oligomerisation domain [IPR035248]", "PRO8NT domain [IPR012591]", "PROCN domain [IPR012592]", "PROCT domain [IPR012984]", "PRP1 splicing factor, N-terminal [IPR010491]", "PRP8 domain IV core [IPR021983]", "PSF, NOPS domain [IPR034526]", "PSF, RNA recognition motif 1 [IPR034525]", "PSI domain [IPR016201]", "PSP, proline-rich [IPR006568]", "PSP1, RNA recognition motif 1 [IPR034522]", "PSP1, RNA recognition motif 2 [IPR034523]", "PTB/PI domain [IPR006020]", "PTBP1, RNA recognition motif 1 [IPR035000]", "PTBP1, RNA recognition motif 2-like [IPR021790]", "PTBP1, RNA recognition motif 3 [IPR035001]", "PTBP2, RNA recognition motif 1 [IPR035002]", "PTBP2, RNA recognition motif 3 [IPR034799]", "PTBP2, RNA recognition motif 4 [IPR034800]", "PUA domain [IPR002478]", "PUF60, RNA recognition motif 1 [IPR034209]", "PUF60, RNA recognition motif 2 [IPR034211]", "PUF60, RNA recognition motif 3 [IPR034212]", "PUL domain [IPR013535]", "PWI domain [IPR002483]", "PWWP domain [IPR000313]", "Paf1 complex subunit Cdc73, N-terminal domain [IPR032041]", "Palladin, C-terminal immunoglobulin-like domain [IPR033017]", "Patatin-like phospholipase domain [IPR002641]", "Patatin-like phospholipase domain containing protein 8-like [IPR045217]", "Pentacotripeptide-repeat region of PRORP [IPR033443]", "Pep3/Vps18/deep orange [IPR007810]", "Peptidase C12, C-terminal domain [IPR041507]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase [IPR001578]", "Peptidase C14, p20 domain [IPR001309]", "Peptidase C14, caspase non-catalytic subunit p10 [IPR002138]", "Peptidase C14A, caspase catalytic domain [IPR015917]", "Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394]", "Peptidase C19, ubiquitin-specific peptidase, DUSP domain [IPR006615]", "Peptidase C1A, papain C-terminal [IPR000668]", "Peptidase C1A, propeptide [IPR012599]", "Peptidase C2, calpain, catalytic domain [IPR001300]", "Peptidase C2, calpain, domain III [IPR022683]", "Peptidase C2, calpain, large subunit, domain III [IPR022682]", "Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal [IPR015211]", "Peptidase M1, membrane alanine aminopeptidase [IPR014782]", "Peptidase M12B, ADAM/reprolysin [IPR001590]", "Peptidase M12B, propeptide [IPR002870]", "Peptidase M13, C-terminal domain [IPR018497]", "Peptidase M13, N-terminal domain [IPR008753]", "Peptidase M14, carboxypeptidase A [IPR000834]", "Peptidase M16, C-terminal [IPR007863]", "Peptidase M16, N-terminal [IPR011765]", "Peptidase M16, middle/third domain [IPR032632]", "Peptidase M16C associated [IPR013578]", "Peptidase M17, leucyl aminopeptidase, C-terminal [IPR000819]", "Peptidase M17, leucyl aminopeptidase, N-terminal [IPR008283]", "Peptidase M20, dimerisation domain [IPR011650]", "Peptidase M24 [IPR000994]", "Peptidase M24, C-terminal domain [IPR032416]", "Peptidase M28 [IPR007484]", "Peptidase M3A/M3B catalytic domain [IPR001567]", "Peptidase M41 [IPR000642]", "Peptidase M41, FtsH extracellular [IPR011546]", "Peptidase M48 [IPR001915]", "Peptidase S16, Lon proteolytic domain [IPR008269]", "Peptidase S24/S26A/S26B/S26C [IPR015927]", "Peptidase S26 [IPR019533]", "Peptidase S53, activation domain [IPR015366]", "Peptidase S59, nucleoporin [IPR007230]", "Peptidase S8/S53 domain [IPR000209]", "Peptidase S8A, tripeptidyl peptidase II [IPR022229]", "Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375]", "Peptidase S9A, N-terminal domain [IPR023302]", "Peptidase family M60 domain [IPR031161]", "Peptide chain release factor class I [IPR000352]", "Peptidyl-prolyl cis-trans isomerase E, RNA recognition motif [IPR034168]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type [IPR000297]", "Pericentrin/AKAP-450 centrosomal targeting domain [IPR019528]", "Pericentriolar material 1 protein, C-terminal [IPR031446]", "Peripheral subunit-binding domain [IPR004167]", "Peroxiredoxin, C-terminal [IPR019479]", "Peroxisome membrane anchor protein Pex14p, N-terminal [IPR006785]", "PheRS DNA binding domain 2 [IPR040586]", "PheRS, DNA binding domain 1 [IPR040724]", "PheRS, DNA binding domain 3 [IPR040725]", "Phenylacetic acid degradation-related domain [IPR003736]", "Phenylalanine--tRNA ligase beta subunit, B1 domain [IPR040659]", "Phenylalanyl tRNA synthetase beta chain, core domain [IPR041616]", "Phenylalanyl-tRNA synthetase [IPR002319]", "Phosducin, thioredoxin-like domain [IPR024253]", "Phosphatidic acid phosphatase type 2/haloperoxidase [IPR000326]", "Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403]", "Phosphatidylinositol 3-kinase Ras-binding (PI3K RBD) domain [IPR000341]", "Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha, PX domain [IPR042133]", "Phosphatidylinositol-4-phosphate 5-kinase, core [IPR002498]", "Phosphatidylinositol-specific phospholipase C, X domain [IPR000909]", "Phosphoadenosine phosphosulphate reductase [IPR002500]", "Phosphoenolpyruvate carboxykinase, C-terminal P-loop domain [IPR035077]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal [IPR035078]", "Phosphofructokinase domain [IPR000023]", "Phosphoglucose isomerase, SIS domain 1 [IPR035476]", "Phosphoglucose isomerase, SIS domain 2 [IPR035482]", "Phosphoinositide 3-kinase, accessory (PIK) domain [IPR001263]", "Phosphoinositide-specific phospholipase C, EF-hand-like domain [IPR015359]", "Phospholipase C, phosphatidylinositol-specific, Y domain [IPR001711]", "Phospholipase C-beta, C-terminal domain [IPR014815]", "Phospholipase D/Transphosphatidylase [IPR001736]", "Phospholipase/carboxylesterase/thioesterase [IPR003140]", "Phospholipid/glycerol acyltransferase [IPR002123]", "Phosphopantetheine binding ACP domain [IPR009081]", "Phosphoribosylformylglycinamidine synthase, N-terminal [IPR040707]", "Phosphoribosylformylglycinamidine synthase, linker domain [IPR041609]", "Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain [IPR020561]", "Phosphoribosylglycinamide synthetase, C-domain [IPR020560]", "Phosphoribosylglycinamide synthetase, N-terminal [IPR020562]", "Phosphoribosyltransferase domain [IPR000836]", "Phosphoribulokinase/uridine kinase [IPR006083]", "Phosphorylated adapter RNA export protein, RNA-binding domain [IPR019385]", "Phosphotyrosine protein phosphatase I [IPR023485]", "Phox homology [IPR001683]", "Pinin/SDK [IPR006787]", "Pinin/SDK/MemA protein [IPR006786]", "Pirin, C-terminal domain [IPR008778]", "Pirin, N-terminal domain [IPR003829]", "Plasma membrane calcium transporting P-type ATPase, C-terminal [IPR022141]", "Pleckstrin homology domain 8 [IPR041680]", "Pleckstrin homology domain 9 [IPR041681]", "Pleckstrin homology domain [IPR001849]", "Pleckstrin homology domain, spectrin-type [IPR001605]", "Plectin/S10, N-terminal [IPR005326]", "Plus-3 domain [IPR004343]", "Polo-like kinase 1, catalytic domain [IPR033702]", "Poly(A) polymerase, RNA-binding domain [IPR007010]", "Poly(A) polymerase, central domain [IPR007012]", "Poly(A)-specific ribonuclease, RNA-binding [IPR014789]", "Poly(ADP-ribose) polymerase, catalytic domain [IPR012317]", "Poly(ADP-ribose) polymerase, regulatory domain [IPR004102]", "Polyadenylate-binding protein/Hyperplastic disc protein [IPR002004]", "Polyamine biosynthesis domain [IPR030374]", "Polycomb group protein, RNA binding region [IPR033763]", "Polycomb protein, VEFS-Box [IPR019135]", "Polyketide synthase, C-terminal extension [IPR032821]", "Polyketide synthase, beta-ketoacyl synthase domain [IPR020841]", "Polyketide synthase, dehydratase domain [IPR020807]", "Polyketide synthase, enoylreductase domain [IPR020843]", "Polyketide synthase, ketoreductase domain [IPR013968]", "Polyketide synthase, phosphopantetheine-binding domain [IPR020806]", "Polymerase, nucleotidyl transferase domain [IPR002934]", "Polynucleotide 3'-phosphatase [IPR006551]", "Polypyrimidine tract-binding protein1/2/3, RNA recognition motif 2 [IPR034798]", "Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain [IPR032319]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain [IPR015848]", "Polysaccharide biosynthesis domain [IPR021148]", "Pop1, N-terminal [IPR009723]", "Porphobilinogen deaminase, C-terminal [IPR022418]", "Porphobilinogen deaminase, N-terminal [IPR022417]", "Possible tRNA binding domain [IPR027992]", "Post-SET domain [IPR003616]", "Potassium channel tetramerisation-type BTB domain [IPR003131]", "Potentiating neddylation domain [IPR005176]", "Pre-PUA domain [IPR041366]", "Pre-SET domain [IPR007728]", "Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term [IPR021718]", "Pre-mRNA polyadenylation factor Fip1 domain [IPR007854]", "Pre-mRNA processing factor 4 (PRP4)-like [IPR014906]", "Pre-mRNA splicing factor component Cdc5p/Cef1, C-terminal [IPR021786]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding [IPR019581]", "Pre-mRNA-processing-splicing factor 8, U6-snRNA-binding [IPR019580]", "Pre-mRNA-splicing factor 19 [IPR013915]", "Pre-mRNA-splicing factor 3 [IPR013881]", "Pre-mRNA-splicing factor SLU7 domain [IPR021715]", "Pre-rRNA-processing protein Ipi1, N-terminal [IPR024679]", "Pre-rRNA-processing protein RIX1, N-terminal [IPR012583]", "Predicted HAD-superfamily phosphatase, subfamily IA/Epoxide hydrolase, N-terminal [IPR011945]", "Prenylcysteine lyase [IPR010795]", "Probable RNA-binding protein 19, RNA recognition motif 1 [IPR034418]", "Probable RNA-binding protein 19, RNA recognition motif 2 [IPR034417]", "Probable RNA-binding protein 19, RNA recognition motif 3 [IPR034419]", "Probable RNA-binding protein 19, RNA recognition motif 4 [IPR034420]", "Probable RNA-binding protein 19, RNA recognition motif 5 [IPR034423]", "Probable RNA-binding protein 19, RNA recognition motif 6 [IPR034421]", "Proliferating cell nuclear antigen, PCNA, C-terminal [IPR022649]", "Proliferating cell nuclear antigen, PCNA, N-terminal [IPR022648]", "Proline-tRNA ligase, class II, C-terminal [IPR016061]", "Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]", "Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547]", "Prolyl 4-hydroxylase, alpha subunit [IPR006620]", "Prolyl-tRNA synthetase, catalytic domain [IPR033721]", "Propionyl-coenzyme A carboxylase, BT domain [IPR041265]", "Prostaglandin E synthase 2, C-terminal [IPR034335]", "Proteasomal ATPase OB C-terminal domain [IPR032501]", "Proteasome activator Blm10, mid region [IPR032430]", "Proteasome activator PA28, C-terminal domain [IPR003186]", "Proteasome activator PA28, N-terminal domain [IPR003185]", "Proteasome activator complex subunit 4 C-terminal domain [IPR021843]", "Proteasome alpha-subunit, N-terminal domain [IPR000426]", "Proteasome beta subunit, C-terminal [IPR024689]", "Proteasome component (PCI) domain [IPR000717]", "Protein HGH1 C-terminal [IPR007206]", "Protein HGH1 N-terminal [IPR007205]", "Protein Kinase B, pleckstrin homology domain [IPR039026]", "Protein O-mannosyl-transferase TMTC, DUF1736 [IPR013618]", "Protein RED, C-terminal [IPR012492]", "Protein RMD5 homologue A, degenerated RING finger [IPR037680]", "Protein Smaug, SAM domain [IPR037634]", "Protein disulfide-isomerase A3, first redox inactive TRX-like domain b [IPR041868]", "Protein disulfide-isomerase A4, TRX-like domain b [IPR041866]", "Protein disulfide-isomerase A5, N-terminal TRX-like b domain [IPR041865]", "Protein furry, C-terminal [IPR045842]", "Protein kinase A anchor protein, nuclear localisation signal domain [IPR019510]", "Protein kinase B alpha, catalytic domain [IPR034676]", "Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219]", "Protein kinase domain [IPR000719]", "Protein kinase, C-terminal [IPR017892]", "Protein of unknown function DUF3504 [IPR021893]", "Protein of unknown function DUF3715 [IPR022188]", "Protein phosphatase 1 binding domain [IPR029334]", "Protein polybromo-1, Bromodomain 5 [IPR037968]", "Protein quaking, putative nuclear localisation signal [IPR032367]", "Protein-only RNase P, C-terminal [IPR031595]", "Protein-tyrosine phosphatase, catalytic [IPR003595]", "Prp31 C-terminal [IPR019175]", "Pseudouridine synthase I, TruA, alpha/beta domain [IPR020097]", "Pseudouridine synthase II, N-terminal [IPR002501]", "Pseudouridine synthase, RsuA/RluA-like [IPR006145]", "Pseudouridine synthase, TruD, insertion domain [IPR011760]", "Pterin-binding domain [IPR000489]", "Pumilio homology domain [IPR033133]", "Pumilio, RNA binding domain [IPR033712]", "PurE domain [IPR000031]", "PurM-like, C-terminal domain [IPR010918]", "PurM-like, N-terminal domain [IPR016188]", "Putative 5-3 exonuclease [IPR004859]", "Putative RNA methylase domain [IPR000241]", "Putative RNA-binding protein 27, RNA recognition motif [IPR034451]", "Putative RNA-binding protein 47, RNA recognition motif 2 [IPR034440]", "Putative RNA-binding protein 47, RNA recognition motif 3 [IPR034445]", "Putative WW-binding domain and destruction box [IPR033461]", "Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain [IPR004099]", "Pyridoxamine 5'-phosphate oxidase, putative [IPR011576]", "Pyridoxamine kinase/Phosphomethylpyrimidine kinase [IPR013749]", "Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal [IPR019576]", "Pyrroline-5-carboxylate reductase, catalytic, N-terminal [IPR028939]", "Pyrroline-5-carboxylate reductase, dimerisation domain [IPR029036]", "Pyruvate carboxyltransferase [IPR000891]", "Pyruvate kinase, C-terminal [IPR015795]", "Pyruvate kinase, barrel [IPR015793]", "R3H domain [IPR001374]", "RABX5, catalytic core helical domain [IPR041545]", "RACK7, Bromo domain [IPR037967]", "RAD23A/RAD23B, UBA1 domain [IPR041811]", "RAD50, zinc hook [IPR013134]", "RAP domain [IPR013584]", "RBM10, OCRE domain [IPR035618]", "RBM12, RNA recognition motif 1 [IPR034591]", "RBM12, RNA recognition motif 2 [IPR034594]", "RBM12, RNA recognition motif 3 [IPR034855]", "RBM12, RNA recognition motif 4 [IPR034856]", "RBM12, RNA recognition motif 5 [IPR034854]", "RBM12B, RNA recognition motif 2 [IPR034588]", "RBM12B, RNA recognition motif 3 [IPR034858]", "RBM14, RNA recognition motif 1 [IPR034506]", "RBM14, RNA recognition motif 2 [IPR034507]", "RBM15, RNA recognition motif 1 [IPR034470]", "RBM15, RNA recognition motif 2 [IPR034472]", "RBM15, RNA recognition motif 3 [IPR034473]", "RBM15B, RNA recognition motif 1 [IPR034475]", "RBM15B, RNA recognition motif 2 [IPR034535]", "RBM15B, RNA recognition motif 3 [IPR034536]", "RBM1CTR [IPR012604]", "RBM25, RNA recognition motif [IPR034268]", "RBM26, RNA recognition motif 1 [IPR034859]", "RBM26-like, RNA recognition motif 2 [IPR039511]", "RBM3/CIRBP, RNA recognition motif [IPR034278]", "RBM34, RNA recognition motif 1 [IPR034220]", "RBM34, RNA recognition motif 2 [IPR034221]", "RBM4, RNA recognition motif 1 [IPR034897]", "RBM4, RNA recognition motif 2 [IPR034898]", "RBM42, RNA recognition motif [IPR034215]", "RBM8, RNA recognition motif [IPR033744]", "RED-like, N-terminal [IPR012916]", "REKLES domain [IPR023334]", "RH1 domain [IPR034743]", "RH2 domain [IPR034744]", "RHIM domain [IPR025735]", "RII binding domain [IPR018459]", "RING finger protein 219, RING finger [IPR035691]", "RING-type zinc-finger, LisH dimerisation motif [IPR027370]", "RIP1, Death domain [IPR037934]", "RL domain [IPR041252]", "RLI, domain 1 [IPR034348]", "RNA 3'-terminal phosphate cyclase domain [IPR023797]", "RNA 3'-terminal phosphate cyclase, insert domain [IPR013791]", "RNA binding activity-knot of a chromodomain [IPR025995]", "RNA exonuclease 4, DEDDh 3'-5' exonuclease domain [IPR037431]", "RNA helicase UPF1, 1B domain [IPR040812]", "RNA helicase UPF1, Cys/His rich zinc-binding domain [IPR018999]", "RNA helicase, DEAD-box type, Q motif [IPR014014]", "RNA methyltransferase bin3, C-terminal [IPR010675]", "RNA polymerase II assembly factor Rtp1, C-terminal [IPR019451]", "RNA polymerase II assembly factor Rtp1, C-terminal domain 2 [IPR019414]", "RNA polymerase II elongation factor ELL, N-terminal [IPR019464]", "RNA polymerase II-associated protein 1, C-terminal [IPR013929]", "RNA polymerase II-associated protein 1, N-terminal [IPR013930]", "RNA polymerase III Rpc82, C -terminal [IPR008806]", "RNA polymerase III subunit RPC82-related, helix-turn-helix [IPR013197]", "RNA polymerase Rpb1, domain 1 [IPR007080]", "RNA polymerase Rpb1, domain 3 [IPR007066]", "RNA polymerase Rpb1, domain 4 [IPR007083]", "RNA polymerase Rpb1, domain 5 [IPR007081]", "RNA polymerase Rpb1, domain 6 [IPR007075]", "RNA polymerase Rpb1, domain 7 [IPR007073]", "RNA polymerase Rpb2, domain 2 [IPR007642]", "RNA polymerase Rpb2, domain 3 [IPR007645]", "RNA polymerase Rpb2, domain 4 [IPR007646]", "RNA polymerase Rpb2, domain 5 [IPR007647]", "RNA polymerase Rpb2, domain 7 [IPR007641]", "RNA polymerase Rpb4/RPC9, core [IPR006590]", "RNA polymerase Rpb7-like , N-terminal [IPR005576]", "RNA polymerase, N-terminal [IPR006592]", "RNA polymerase, Rpb5, N-terminal [IPR005571]", "RNA polymerase, alpha subunit [IPR000722]", "RNA polymerase, beta subunit, protrusion [IPR007644]", "RNA polymerase, subunit H/Rpb5 C-terminal [IPR000783]", "RNA recognition motif domain [IPR000504]", "RNA recognition motif domain, eukaryote [IPR003954]", "RNA recognition motif, spliceosomal PrP8 [IPR019582]", "RNA-binding S4 domain [IPR002942]", "RNA-binding domain, S1 [IPR022967]", "RNA-binding protein 10, RNA recognition motif 2 [IPR034992]", "RNA-binding protein 5, RNA recognition motif 1 [IPR034991]", "RNA-binding protein 5, RNA recognition motif 2 [IPR034993]", "RNA-binding protein Musashi homologue, RNA recognition motif 1 [IPR034130]", "RNA-binding protein Musashi homologue, RNA recognition motif 2 [IPR034126]", "RNA-polymerase II-associated protein 3-like, C-terminal domain [IPR025986]", "RNA-recognition motif (RRM) Nup35-type domain [IPR007846]", "RNPS1, RNA recognition motif [IPR034201]", "RNase L inhibitor RLI-like, possible metal-binding domain [IPR007209]", "ROCK, Rho binding domain [IPR015008]", "ROK, N-terminal [IPR012987]", "RPN1, N-terminal [IPR040892]", "RPN13, DEUBAD domain [IPR032368]", "RQC domain [IPR018982]", "RUN domain [IPR004012]", "RWD domain [IPR006575]", "RZZ complex, subunit KNTC1/ROD, C-terminal [IPR019527]", "Rab geranylgeranyltransferase, alpha subunit, insert-domain [IPR009087]", "Rab-GTPase-TBC domain [IPR000195]", "Rab-binding domain FIP-RBD [IPR019018]", "Rab3-GAP regulatory subunit, N-terminal [IPR032839]", "Rab3GAP catalytic subunit, C-terminal [IPR045698]", "Rab3GAP catalytic subunit, conserved domain [IPR026147]", "Rab3GAP regulatory subunit, C-terminal [IPR029257]", "Rabaptin coiled-coil domain [IPR018514]", "Rabaptin, GTPase-Rab5 binding domain [IPR015390]", "Rad21/Rec8-like protein, C-terminal, eukaryotic [IPR006909]", "Rad21/Rec8-like protein, N-terminal [IPR006910]", "Rad50, ATP-binding cassette domain [IPR045171]", "Rad50/SbcC-type AAA domain [IPR038729]", "Rad60/SUMO-like domain [IPR022617]", "Radical SAM [IPR007197]", "Raly, RNA recognition motif [IPR034502]", "Ran binding domain [IPR000156]", "Ran binding protein 9/10, SPRY domain [IPR035782]", "Ran-GTPase activating protein 1, C-terminal [IPR009109]", "Ran-specific GTPase-activating protein 1, Ran-binding domain [IPR045256]", "Rap/Ran-GAP domain [IPR000331]", "Rap1 Myb domain [IPR015010]", "Raptor, N-terminal CASPase-like domain [IPR029347]", "Ras GTPase-activating domain [IPR001936]", "Ras guanine-nucleotide exchange factors catalytic domain [IPR001895]", "Ras-associating (RA) domain [IPR000159]", "Ras-like guanine nucleotide exchange factor, N-terminal [IPR000651]", "RasGAP protein, C-terminal [IPR000593]", "RecF/RecN/SMC, N-terminal [IPR003395]", "RecQ helicase-like 5 [IPR010716]", "Receptor L-domain [IPR000494]", "Redoxin [IPR013740]", "Rel homology dimerisation domain [IPR032397]", "Rel homology domain (RHD), DNA-binding domain [IPR011539]", "Replication factor A, C-terminal [IPR013955]", "Replication factor C, C-terminal [IPR013748]", "Replication factor Mcm10, C-terminal [IPR015411]", "Replication factor-A protein 1, N-terminal [IPR007199]", "Replication protein A, C-terminal [IPR014892]", "Replication protein A, OB domain [IPR031657]", "Replication termination factor 2, RING-finger [IPR027799]", "Reticulon [IPR003388]", "Rho GTPase-activating protein domain [IPR000198]", "Rho GTPase-activating protein, FF domain [IPR032835]", "Rho GTPase-activating protein, pG1 and pG2 domain [IPR045786]", "Rho GTPase-activating protein, pG1 domain [IPR039007]", "Rho GTPase-activating protein, pG2 domain [IPR039006]", "Rho GTPase-binding/formin homology 3 (GBD/FH3) domain [IPR014768]", "Rho-associated protein kinase 1, HR1 [IPR037310]", "Rho-associated protein kinase 2, HR1 domain [IPR037311]", "Rhodanese-like domain [IPR001763]", "Ribonuclease H1, N-terminal [IPR011320]", "Ribonuclease H2 subunit B, wHTH domain [IPR019024]", "Ribonuclease HII/HIII domain [IPR024567]", "Ribonuclease II/R [IPR001900]", "Ribonuclease III domain [IPR000999]", "Ribonuclease, PIN domain [IPR033411]", "Ribonucleoprotein PTB-binding 1, RNA recognition motif 1 [IPR034633]", "Ribonucleotide reductase large subunit, C-terminal [IPR000788]", "Ribonucleotide reductase large subunit, N-terminal [IPR013509]", "Ribonucleotide reductase, class I , alpha subunit [IPR013346]", "Ribose-phosphate pyrophosphokinase, N-terminal domain [IPR029099]", "Ribosomal L28e/Mak16 [IPR029004]", "Ribosomal Protein L6, KOW domain [IPR041997]", "Ribosomal Proteins L2, RNA binding domain [IPR022666]", "Ribosomal RNA adenine methylase transferase, N-terminal [IPR020598]", "Ribosomal RNA methyltransferase FtsJ domain [IPR002877]", "Ribosomal RNA methyltransferase Spb1, domain of unknown function DUF3381 [IPR024576]", "Ribosomal RNA methyltransferase, Spb1, C-terminal [IPR012920]", "Ribosomal RNA small subunit methyltransferase F, N-terminal [IPR031341]", "Ribosomal RNA-processing protein 14/surfeit locus protein 6, C-terminal domain [IPR029190]", "Ribosomal S6 kinase, N-terminal catalytic domain [IPR041906]", "Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A [IPR023573]", "Ribosomal protein L10e/L16 [IPR016180]", "Ribosomal protein L11, C-terminal [IPR020783]", "Ribosomal protein L11, N-terminal [IPR020784]", "Ribosomal protein L14, KOW motif [IPR041985]", "Ribosomal protein L14e domain [IPR002784]", "Ribosomal protein L18e/L15P [IPR021131]", "Ribosomal protein L19, eukaryotic [IPR033935]", "Ribosomal protein L19/L19e [IPR000196]", "Ribosomal protein L2, C-terminal [IPR022669]", "Ribosomal protein L23/L25, N-terminal [IPR005633]", "Ribosomal protein L26/L24, KOW domain [IPR041988]", "Ribosomal protein L30, N-terminal [IPR012988]", "Ribosomal protein L30, ferredoxin-like fold domain [IPR016082]", "Ribosomal protein L46, N-terminal [IPR021757]", "Ribosomal protein L5 eukaryotic, C-terminal [IPR025607]", "Ribosomal protein L5, C-terminal [IPR031309]", "Ribosomal protein L5, N-terminal [IPR031310]", "Ribosomal protein L6, N-terminal [IPR005568]", "Ribosomal protein L6, alpha-beta domain [IPR020040]", "Ribosomal protein L7, eukaryotic/archaeal [IPR035808]", "Ribosomal protein L7/L12, C-terminal [IPR013823]", "Ribosomal protein L7/L12, oligomerisation [IPR008932]", "Ribosomal protein L7Ae/L30e/S12e/Gadd45 [IPR004038]", "Ribosomal protein L9, N-terminal [IPR020070]", "Ribosomal protein S10 domain [IPR027486]", "Ribosomal protein S13/S15, N-terminal [IPR012606]", "Ribosomal protein S23/S25, mitochondrial [IPR023611]", "Ribosomal protein S24/S35, mitochondrial, conserved domain [IPR019349]", "Ribosomal protein S3, C-terminal [IPR001351]", "Ribosomal protein S4, KOW domain [IPR041982]", "Ribosomal protein S4/S9, N-terminal [IPR001912]", "Ribosomal protein S4e, N-terminal [IPR013843]", "Ribosomal protein S4e, central region [IPR013845]", "Ribosomal protein S5, C-terminal [IPR005324]", "Ribosomal protein S5, N-terminal [IPR013810]", "Ribosomal protein S6 kinase alpha-3, C-terminal catalytic domain [IPR041905]", "Ribosomal protein S7 domain [IPR023798]", "Ribosomal protein/NADH dehydrogenase domain [IPR007741]", "Ribosome biogenesis protein BMS1/TSR1, C-terminal [IPR007034]", "Ribosome biogenesis protein Bms1, N-terminal [IPR037875]", "Ribosome maturation protein Sdo1/SBDS, C-terminal [IPR018978]", "Ribosome maturation protein Sdo1/SBDS, N-terminal [IPR019783]", "Ribosome receptor lysine/proline rich [IPR007794]", "Ribosome recycling factor domain [IPR023584]", "Ribosome-associated complex head domain [IPR032003]", "Ricin B, lectin domain [IPR000772]", "Rieske iron-sulphur protein, C-terminal [IPR005805]", "Right handed beta helix domain [IPR039448]", "RmlD-like substrate binding domain [IPR029903]", "Rnh202, triple barrel domain [IPR041195]", "Roadblock/LAMTOR2 domain [IPR004942]", "Rpa43, N-terminal ribonucleoprotein (RNP) domain [IPR041901]", "Rpn11/EIF3F, C-terminal [IPR024969]", "Rpn13/ADRM1, Pru domain [IPR044868]", "Rrp40, S1 domain [IPR037319]", "Rrp44-like cold shock domain [IPR033771]", "RuvB-like, AAA-lid domain [IPR041048]", "S-adenosyl-L-homocysteine hydrolase, NAD binding domain [IPR015878]", "S-adenosylmethionine synthetase, C-terminal [IPR022630]", "S-adenosylmethionine synthetase, N-terminal [IPR022628]", "S-adenosylmethionine synthetase, central domain [IPR022629]", "S1 domain [IPR003029]", "S1-like RNA binding domain [IPR025223]", "S100/CaBP-9k-type, calcium binding, subdomain [IPR013787]", "SAB domain [IPR007477]", "SAC domain [IPR002013]", "SAF domain [IPR013974]", "SAICAR synthetase/ADE2, N-terminal [IPR028923]", "SAM domain [IPR041418]", "SAM-dependent methyltransferase RsmB/NOP2-type [IPR001678]", "SANT domain [IPR017884]", "SANT/Myb domain [IPR001005]", "SAP domain [IPR003034]", "SARAH domain [IPR011524]", "SART3, RNA recognition motif 1 [IPR034217]", "SART3, RNA recognition motif 2 [IPR034218]", "SAS-6 coiled-coil domain [IPR041513]", "SCAF4, RNA recognition motif [IPR034369]", "SCAN domain [IPR003309]", "SCP2 sterol-binding domain [IPR003033]", "SDA1 domain [IPR007949]", "SEC23-interacting protein, SAM domain [IPR037603]", "SEP domain [IPR012989]", "SERRATE/Ars2 , C-terminal [IPR007042]", "SERRATE/Ars2, N-terminal [IPR021933]", "SET domain [IPR001214]", "SETD7, SET domain [IPR044436]", "SF3A2 domain [IPR031781]", "SF3A3 domain [IPR031774]", "SF3B4, RNA recognition motif 1 [IPR034158]", "SF3B4, RNA recognition motif 2 [IPR034159]", "SF3B6, RNA recognition motif [IPR034150]", "SGNH hydrolase-type esterase domain [IPR013830]", "SGS domain [IPR007699]", "SGTA, homodimerisation domain [IPR032374]", "SH2 domain [IPR000980]", "SH3 domain [IPR001452]", "SH3-like domain, bacterial-type [IPR003646]", "SH3PXD2, PX domain [IPR037961]", "SH3PXD2B, SH3 domain 1 [IPR035477]", "SH3PXD2B, SH3 domain 2 [IPR035478]", "SH3PXD2B, SH3 domain 3 [IPR035479]", "SH3PXD2B, SH3 domain 4 [IPR035480]", "SHARP, RNA recognition motif 1 [IPR034172]", "SHARP, RNA recognition motif 2 [IPR034173]", "SHARP, RNA recognition motif 3 [IPR034174]", "SHARP, RNA recognition motif 4 [IPR034175]", "SIR2-like domain [IPR039444]", "SIS domain [IPR001347]", "SKI-interacting protein SKIP, SNW domain [IPR004015]", "SKP1 component, POZ domain [IPR016073]", "SKP1 component, dimerisation [IPR016072]", "SLC12A transporter, C-terminal [IPR018491]", "SLED domain [IPR021987]", "SLIDE domain [IPR015195]", "SLIRP, RNA recognition motif [IPR034152]", "SMAP1-like, ArfGAP domain [IPR044732]", "SMARCA1, N-terminal [IPR044755]", "SMARCC, C-terminal [IPR032451]", "SMARCC, N-terminal [IPR032450]", "SMARCC, SWIRM-associated domain [IPR032448]", "SMCs flexible hinge [IPR010935]", "SNAP-25 domain [IPR000928]", "SNARE-complex protein Syntaxin-18, N-terminal [IPR019529]", "SNF2, N-terminal [IPR000330]", "SNX17, atypical FERM-like domain [IPR037836]", "SNX2, PX domain [IPR037918]", "SNX27, PX domain [IPR037833]", "SNX27, RA domain [IPR037835]", "SNX27, atypical FERM-like domain [IPR037827]", "SNX5, PX domain [IPR042135]", "SNX6, PX domain [IPR042136]", "SNX9, SH3 domain [IPR035558]", "SOCS box domain [IPR001496]", "SPF45, RNA recognition motif [IPR034653]", "SPRY domain [IPR003877]", "SPRY-associated [IPR006574]", "SR140, RNA recognition motif [IPR035009]", "SRA-YDG [IPR003105]", "SRCR domain [IPR001190]", "SRCR-like domain [IPR017448]", "SREK1, RNA recognition motif 2 [IPR034192]", "SRP9 domain [IPR039432]", "SRSF1, RNA recognition motif 1 [IPR034520]", "SRSF6, RNA recognition motif 1 [IPR034511]", "SRSF7, RNA recognition motif [IPR034651]", "SRSF9, RNA recognition motif 1 [IPR034503]", "SRSF9, RNA recognition motif 2 [IPR034995]", "SSRP1 domain [IPR024954]", "STAG [IPR013721]", "STAM1, SH3 domain [IPR035657]", "STAMBP/STALP-like, MPN domain [IPR044098]", "STAR protein, homodimerisation region [IPR032377]", "STARD7, START domain [IPR041949]", "START domain [IPR002913]", "STAT transcription factor, DNA-binding [IPR013801]", "STAT transcription factor, all-alpha domain [IPR013800]", "STAT transcription factor, protein interaction [IPR013799]", "STAT1, SH2 domain [IPR035859]", "STAT3, SH2 domain [IPR035855]", "STI1 domain [IPR041243]", "STRBP, first double-stranded RNA binding domain [IPR044472]", "SUI1 domain [IPR001950]", "SUMO-activating enzyme subunit 2, C-terminal domain [IPR032426]", "SUN coiled coil domain 2 [IPR040994]", "SUN domain [IPR012919]", "SUN domain-containing protein 1, N-terminal [IPR032680]", "SUZ-C domain [IPR024642]", "SWAP/Surp [IPR000061]", "SWI/SNF-like complex subunit BAF250, C-terminal [IPR033388]", "SWIRM domain [IPR007526]", "Saccharopine dehydrogenase, NADP binding domain [IPR005097]", "Saccharopine dehydrogenase-like, C-terminal [IPR032095]", "Sam68, tyrosine-rich domain [IPR032335]", "Saposin A-type domain [IPR003119]", "Saposin B type domain [IPR008139]", "Saposin B type, region 2 [IPR008138]", "Saposin-like type B, region 1 [IPR007856]", "Scaffold protein Nfu/NifU, N-terminal [IPR014824]", "Schlafen group 3-like, DNA/RNA helicase domain [IPR018647]", "Schlafen, AlbA_2 domain [IPR007421]", "Sec16, central conserved domain [IPR024340]", "Sec23, C-terminal [IPR037550]", "Sec23/Sec24 beta-sandwich [IPR012990]", "Sec23/Sec24, helical domain [IPR006900]", "Sec23/Sec24, trunk domain [IPR006896]", "Sec24-like, trunk domain [IPR041742]", "Sec39 domain [IPR013244]", "Sec63 domain [IPR004179]", "Sec7 domain [IPR000904]", "Sec8 exocyst complex component specific domain [IPR007191]", "Second polo-box domain [IPR033695]", "Sedolisin domain [IPR030400]", "Senescence/spartin-associated, C-terminal [IPR009686]", "Sentrin-specific protease 3/5, conserved domain [IPR045577]", "Septin-type guanine nucleotide-binding (G) domain [IPR030379]", "Sequestosome-1, PB1 domain [IPR034866]", "Sequestosome-1, UBA domain [IPR033741]", "Serine aminopeptidase, S33 [IPR022742]", "Serine hydroxymethyltransferase-like domain [IPR039429]", "Serine-tRNA ligase catalytic core domain [IPR033729]", "Serine-tRNA synthetase, type1, N-terminal [IPR015866]", "Serine-threonine protein phosphatase, N-terminal [IPR031675]", "Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245]", "Serine/arginine-rich splicing factor SRSF4-like, RNA recognition motif 1 [IPR035585]", "Serine/threonine-protein PRP4, catalytic domain [IPR044092]", "Serine/threonine-protein kinase MRCK beta, catalytic domain [IPR042718]", "Serine/threonine-protein kinase N, C2 domain [IPR037784]", "Serine/threonine-protein kinase N, first HR1 domain [IPR037313]", "Serine/threonine-protein kinase N1, second HR1 domain [IPR037317]", "Serine/threonine-protein kinase Nek9, catalytic domain [IPR042767]", "Serine/threonine-protein kinase OSR1/WNK, CCT domain [IPR024678]", "Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase [IPR006186]", "Serpin H1, serpin domain [IPR033830]", "Serpin domain [IPR023796]", "Siah interacting protein, N-terminal [IPR015120]", "Signal recognition particle SRP54, helical bundle [IPR013822]", "Signal recognition particle receptor, alpha subunit, N-terminal [IPR007222]", "Signal recognition particle subunit SRP68, RNA-binding domain [IPR034652]", "Signal recognition particle, SRP54 subunit, GTPase domain [IPR000897]", "Signal recognition particle, SRP54 subunit, M-domain [IPR004125]", "Signal recognition particle, SRP72 subunit, RNA-binding [IPR013699]", "Signal transducer and activation of transcription 1, TAZ2 binding domain, C-terminal [IPR022752]", "Sin3, C-terminal [IPR031693]", "Sirtuin family, catalytic core domain [IPR026590]", "Sister chromatid cohesion C-terminal domain [IPR024986]", "Ski2, N-terminal domain [IPR040801]", "Small G protein signalling modulator 1/2, Rab-binding domain [IPR021935]", "Small GTP-binding protein domain [IPR005225]", "Small acidic protein-like domain [IPR028124]", "Small nuclear ribonucleoprotein D1 [IPR034102]", "Small-subunit processome, Utp12 [IPR007148]", "Small-subunit processome, Utp13 [IPR013934]", "Small-subunit processome, Utp21 [IPR007319]", "Smc1, ATP-binding cassette domain [IPR028468]", "Smc2, ATP-binding cassette domain [IPR027120]", "Snf2, ATP coupling domain [IPR029295]", "Snu114, GTP-binding domain [IPR044121]", "Solute carrier family 3 member 2, N-terminal domain [IPR031984]", "Sortilin, C-terminal [IPR031777]", "Sortilin, N-terminal [IPR031778]", "Sorting Nexin 1, PX domain [IPR034901]", "Sorting nexin 4, PX domain [IPR034902]", "Sorting nexin Vps5-like, C-terminal [IPR015404]", "Sorting nexin protein, WASP-binding domain [IPR019497]", "Sorting nexin, N-terminal [IPR005329]", "Sorting nexin-17/31, FERM domain [IPR040842]", "Sorting nexin-4, BAR domain [IPR037430]", "Sorting nexin-9, BAR domain [IPR037425]", "Sorting nexin-9, PX domain [IPR037426]", "Spen paralogue and orthologue SPOC, C-terminal [IPR012921]", "Spen paralogue/orthologue C-terminal, metazoa [IPR010912]", "Spermidine synthase, tetramerisation domain [IPR035246]", "Spermine synthase, N-terminal [IPR040900]", "Spindle assembly abnormal protein 6, N-terminal [IPR032396]", "Splicing factor 1, helix-hairpin domain [IPR032570]", "Splicing factor 3A subunit 1, conserved domain [IPR022030]", "Splicing factor 3A subunit 1, ubiquitin domain [IPR035563]", "Splicing factor 3B subunit 1 [IPR015016]", "Splicing factor ELAV/Hu, RNA recognition motif 1 [IPR034775]", "Splicing factor RBM39, linker [IPR029123]", "Splicing factor SF3a60 /Prp9 subunit, C-terminal [IPR024598]", "Splicing factor SF3a60 binding domain [IPR021966]", "Spp2/MOS2, G-patch domain [IPR026822]", "Spt5 C-terminal domain [IPR024945]", "Spt5 transcription elongation factor, N-terminal [IPR022581]", "Spt5, KOW domain repeat 1 [IPR041973]", "Spt5, KOW domain repeat 2 [IPR041975]", "Spt5, KOW domain repeat 3 [IPR041976]", "Spt5, KOW domain repeat 4 [IPR041977]", "Spt5, KOW domain repeat 5 [IPR041978]", "Spt5, KOW domain repeat 6 [IPR041980]", "Spt6 acidic, N-terminal domain [IPR028083]", "Spt6, SH2 domain [IPR035420]", "Spt6, SH2 domain, C terminus [IPR035018]", "Spt6, SH2 domain, N terminus [IPR035019]", "Squalene cyclase, C-terminal [IPR032696]", "Squalene cyclase, N-terminal [IPR032697]", "Squalene epoxidase [IPR013698]", "Srp40, C-terminal [IPR007718]", "Staphylococcal nuclease (SNase-like), OB-fold [IPR016071]", "Staufen 1, third double-stranded RNA binding domain [IPR044475]", "Staufen, C-terminal [IPR032478]", "Steadiness box (SB) domain [IPR017916]", "Sterile alpha motif domain [IPR001660]", "Sterol-sensing domain [IPR000731]", "Strawberry notch, AAA domain [IPR039187]", "Strawberry notch, helicase C domain [IPR026937]", "Striatin, N-terminal [IPR013258]", "Strictosidine synthase, conserved region [IPR018119]", "Stromalin conservative domain [IPR020839]", "Structural maintenance of chromosomes 3, ABC domain, eukaryotic [IPR041741]", "Structural maintenance of chromosomes 4, ABC domain, eukaryotic [IPR041738]", "Succinate dehydogenase/fumarate reductase N-terminal [IPR025192]", "Sulfatase, N-terminal [IPR000917]", "Sulfhydryl oxidase, Trx-like domain [IPR041269]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain [IPR040986]", "Sulphate adenylyltransferase [IPR002650]", "Sulphate adenylyltransferase catalytic domain [IPR024951]", "Suppressor of forked [IPR008847]", "Suppressor of white apricot, N-terminal domain [IPR019147]", "Survival motor neuron [IPR010304]", "Suv3, C-terminal domain 1 [IPR041082]", "Suv3, DEXQ-box helicase domain [IPR044774]", "Suv3, N-terminal [IPR041453]", "Symplekin C-terminal [IPR022075]", "Symplekin/Pta1, N-terminal [IPR032460]", "Synaptic functional regulator FMRP, KH0 domain [IPR040472]", "Synaptotagmin, SMP domain [IPR039010]", "Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468]", "Synembryn [IPR008376]", "Syntaxin 6, N-terminal [IPR015260]", "Syntaxin, N-terminal domain [IPR006011]", "Syntaxin-8, SNARE domain [IPR041875]", "TANK binding kinase 1, ubiquitin-like domain [IPR041087]", "TANK-binding kinase 1, coiled-coil domain 1 [IPR041309]", "TAP C-terminal (TAP-C) domain [IPR005637]", "TAR DNA-binding protein 43, N-terminal [IPR041105]", "TATA box binding protein associated factor (TAF) [IPR004823]", "TATA element modulatory factor 1, TATA binding [IPR022091]", "TATA-binding protein interacting (TIP20) [IPR013932]", "TBC1D8B, PH-GRAM domain 1 [IPR036012]", "TBC1D8B, PH-GRAM domain 2 [IPR036015]", "TBCE, ubiquitin-like (Ubl) domain [IPR044079]", "TCB1D9/TCB1D9B, PH-GRAM domain 1 [IPR036014]", "TCB1D9/TCB1D9B, PH-GRAM domain 2 [IPR036017]", "TDRD7, third LOTUS domain [IPR037978]", "TFG box [IPR025768]", "TFG, PB1 domain [IPR034857]", "TFIIF beta subunit, HTH domain [IPR040450]", "TFIIF, beta subunit, N-terminal [IPR040504]", "TGS [IPR004095]", "THIF-type NAD/FAD binding fold [IPR000594]", "THO complex subunit 2, N-terminal domain [IPR032302]", "THO complex, subunitTHOC2, C-terminal [IPR021418]", "THO complex, subunitTHOC2, N-terminal [IPR021726]", "THUMP domain [IPR004114]", "TIA-1, RNA recognition motif 2 [IPR034830]", "TIA-1, RNA recognition motif 3 [IPR034832]", "TIAR, RNA recognition motif 1 [IPR034492]", "TIAR, RNA recognition motif 2 [IPR034494]", "TIAR, RNA recognition motif 3 [IPR034496]", "TIF1-beta, RING finger, HC subclass [IPR042713]", "TIP49, P-loop domain [IPR010339]", "TOG domain [IPR034085]", "TOPK, catalytic domain [IPR041989]", "TOPRIM domain [IPR006171]", "TPX2 central domain [IPR027330]", "TPX2, C-terminal [IPR027329]", "TRAM domain [IPR002792]", "TRAM/LAG1/CLN8 homology domain [IPR006634]", "TRAM1-like protein [IPR013599]", "TRASH domain [IPR011017]", "TRF2-interacting telomeric protein/Rap1, C-terminal [IPR021661]", "TRIAD supradomain [IPR044066]", "TRIM21, PRY/SPRY domain [IPR035831]", "TRIM25, PRY/SPRY domain [IPR042753]", "TRIM27, PRY/SPRY domain [IPR035791]", "TRIM4, PRY/SPRY domain [IPR035829]", "TRMT2A, RNA recognition motif [IPR034262]", "TROVE domain [IPR008858]", "TSG101 and ALIX binding domain of CEP55 [IPR022008]", "TUG ubiquitin-like domain [IPR021569]", "TUTase nucleotidyltransferase domain [IPR045100]", "Talin, N-terminal F0 domain [IPR032425]", "Talin, central [IPR015224]", "Talin-1/2, rod-segment [IPR037438]", "Tankyrase 1-binding protein, C-terminal [IPR032764]", "Target SNARE coiled-coil homology domain [IPR000727]", "TatSF1-like, RNA recognition motif 1 [IPR034392]", "TauD/TfdA-like domain [IPR003819]", "Telomere length regulation protein, conserved domain [IPR019337]", "Telomere repeat-binding factor, dimerisation domain [IPR013867]", "Telomere-associated protein Rif1, N-terminal [IPR022031]", "Telomeric repeat-binding factor 2, Rap1-binding domain [IPR031902]", "Tensin phosphatase, C2 domain [IPR014020]", "Tensin-type phosphatase domain [IPR029023]", "Testin, LIM domain 1 [IPR034958]", "Testin, LIM domain 2 [IPR034959]", "Testin, LIM domain 3 [IPR034960]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain [IPR020631]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain [IPR020630]", "Tetrapyrrole methylase [IPR000878]", "Tetratricopeptide repeat-like domain [IPR018704]", "Tetratricopeptide, SHNi-TPR domain [IPR019544]", "Tex protein, YqgF-like domain [IPR032639]", "Tex, S1 domain [IPR044146]", "Tex-like protein, N-terminal [IPR018974]", "Tfc3, extended winged-helix domain [IPR035625]", "Thg1 C-terminal domain [IPR025845]", "Thiamine pyrophosphate enzyme, C-terminal TPP-binding [IPR011766]", "Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain [IPR012001]", "Thiamine pyrophosphate enzyme, central domain [IPR012000]", "Thioesterase [IPR001031]", "Thioesterase domain [IPR006683]", "Thiolase, C-terminal [IPR020617]", "Thiolase, N-terminal [IPR020616]", "Thioredoxin domain [IPR013766]", "Thioredoxin domain-containing protein 17-like domain [IPR010357]", "Thioredoxin-like fold [IPR012336]", "Thioredoxin-related transmembrane protein 2, thioredoxin domain [IPR037463]", "Threonine-tRNA ligase catalytic core domain [IPR033728]", "Threonyl/alanyl tRNA synthetase, SAD [IPR012947]", "Thymidylate kinase-like domain [IPR039430]", "Thymidylate synthase/dCMP hydroxymethylase domain [IPR023451]", "Tim10-like [IPR004217]", "Tim44-like domain [IPR007379]", "Timeless, C-terminal [IPR007725]", "Timeless, N-terminal [IPR006906]", "Toll-interacting protein, C2 domain [IPR037301]", "Toll-interacting protein, CUE domain [IPR041799]", "Topoisomerase I C-terminal domain [IPR025834]", "Trafficking protein particle complex subunit 11 [IPR021773]", "Trafficking protein particle complex subunit 11, C-terminal [IPR025876]", "Trans-isoprenyl diphosphate synthases, head-to-head [IPR033904]", "Transcription elongation factor S-II, central domain [IPR003618]", "Transcription elongation factor Spt6, YqgF domain [IPR028231]", "Transcription elongation factor Spt6, helix-hairpin-helix motif [IPR032706]", "Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type [IPR003617]", "Transcription factor CBF/NF-Y/archaeal histone domain [IPR003958]", "Transcription factor CP2, SAM domain [IPR037599]", "Transcription factor IIIC subunit 5, HTH domain [IPR019136]", "Transcription factor IIIC subunit Tfc1/Sfc1, triple barrel domain [IPR041499]", "Transcription factor IIIC, 90kDa subunit, N-terminal [IPR024761]", "Transcription factor IIIC, putative zinc-finger [IPR024764]", "Transcription factor IIS, N-terminal [IPR017923]", "Transcription factor TFIIB, cyclin-like domain [IPR013150]", "Transcription termination and cleavage factor, C-terminal domain [IPR026896]", "Transcriptional coactivator p15 (PC4), C-terminal [IPR003173]", "Transcriptional repressor p66, coiled-coil MBD2-interaction domain [IPR032346]", "Transferrin receptor protein 1/2, PA domain [IPR037324]", "Transferrin receptor-like, dimerisation domain [IPR007365]", "Transforming acidic coiled-coil-containing protein, C-terminal [IPR007707]", "Transketolase, C-terminal domain [IPR033248]", "Transketolase, N-terminal [IPR005474]", "Transketolase-like, pyrimidine-binding domain [IPR005475]", "Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain [IPR014038]", "Translation elongation factor EFG/EF2, domain IV [IPR005517]", "Translation elongation factor EFTs/EF1B, dimerisation [IPR014039]", "Translation elongation factor EFTu-like, domain 2 [IPR004161]", "Translation elongation factor EFTu/EF1A, C-terminal [IPR004160]", "Translation elongation factor, IF5A C-terminal [IPR020189]", "Translation initiation factor IF- 2, domain 3 [IPR023115]", "Translation initiation factor IF-2, domain II [IPR044145]", "Translation initiation factor IF2/IF5 domain [IPR002735]", "Translation initiation factor eIF-2B subunit epsilon, N-terminal [IPR035543]", "Translation initiation factor eIF-2B subunit epsilon, W2 domain [IPR044123]", "Translation initiation factor, beta propellor-like domain [IPR013979]", "Translational (tr)-type GTP-binding domain [IPR000795]", "Translationally controlled tumour protein (TCTP) domain [IPR034737]", "Translocon Sec61/SecY, plug domain [IPR019561]", "Transmembrane protein 201, C-terminal [IPR018861]", "Treacle protein domain [IPR003993]", "Tripartite DENN domain [IPR037516]", "Tripeptidyl-peptidase II domain [IPR034051]", "TrmE-type guanine nucleotide-binding domain [IPR031168]", "TryX and NRX, thioredoxin domain [IPR045870]", "Tuberin, N-terminal [IPR024584]", "Tuberin-type domain [IPR018515]", "Tubulin binding cofactor C-like domain [IPR012945]", "Tubulin-folding cofactor B, N-terminal ubiquitin-like domain [IPR045172]", "Tubulin-specific chaperone C, N-terminal [IPR031925]", "Tubulin-specific chaperone D, C-terminal [IPR022577]", "Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]", "Tubulin/FtsZ, GTPase domain [IPR003008]", "Tudor domain [IPR002999]", "Tuftelin interacting protein, N-terminal domain [IPR022159]", "Tumour suppressor p53-binding protein-1 Tudor domain [IPR015125]", "Tyrosine-protein kinase BAZ1B, bromodomain [IPR037375]", "Tyrosine-protein kinase, catalytic domain [IPR020635]", "Tyrosine-specific protein phosphatase, PTPase domain [IPR000242]", "Tyrosine-specific protein phosphatases domain [IPR000387]", "U-box domain [IPR003613]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 1 [IPR034407]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 2 [IPR034409]", "U1 small nuclear ribonucleoprotein of 70kDa N-terminal [IPR022023]", "U1-C, C2H2-type zinc finger [IPR013085]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 2 [IPR034562]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 1 [IPR034564]", "U2A'/phosphoprotein 32 family A, C-terminal [IPR003603]", "U3 small nucleolar RNA-associated protein 10, N-terminal [IPR022125]", "U3 small nucleolar RNA-associated protein 15, C-terminal [IPR018983]", "UAS [IPR006577]", "UBAC1, UBA domain 1 [IPR041926]", "UBAC1, UBA domain 2 [IPR041927]", "UBX domain [IPR001012]", "UBXN1, UBA domain [IPR041923]", "UDP-N-acetylglucosamine 2-epimerase domain [IPR003331]", "UDP-glucose/GDP-mannose dehydrogenase, C-terminal [IPR014027]", "UDP-glucose/GDP-mannose dehydrogenase, N-terminal [IPR001732]", "UDP-glucose/GDP-mannose dehydrogenase, dimerisation [IPR014026]", "UDP-glucose:glycoprotein glucosyltransferase, thioredoxin-like domain 4 [IPR040525]", "UGGT, thioredoxin-like domain 1 [IPR040693]", "UGGT, thioredoxin-like domain 2 [IPR040694]", "UGGT, thioredoxin-like domain 3 [IPR040692]", "UHRF1, tandem tudor domain [IPR021991]", "UNC-45/Cro1/She4, central domain [IPR024660]", "UPF0113, PUA domain [IPR005155]", "UPF0113, pre-PUA domain [IPR040598]", "UPF3 domain [IPR005120]", "UPF3B, RNA recognition motif-like domain [IPR034979]", "USP8 dimerisation domain [IPR015063]", "UVR domain [IPR001943]", "Ubiquinol-cytochrome c reductase 8kDa, N-terminal [IPR015248]", "Ubiquinol-cytochrome c reductase, iron-sulphur subunit [IPR006317]", "Ubiquitin E2 variant, N-terminal [IPR008883]", "Ubiquitin carboxyl-terminal hydrolase 47, C-terminal [IPR045578]", "Ubiquitin carboxyl-terminal hydrolase 5, UBA1 domain [IPR041812]", "Ubiquitin carboxyl-terminal hydrolase 7, ICP0-binding domain [IPR024729]", "Ubiquitin carboxyl-terminal hydrolase, C-terminal [IPR029346]", "Ubiquitin conjugation factor E4, core [IPR019474]", "Ubiquitin specific protease domain [IPR028889]", "Ubiquitin system component CUE [IPR003892]", "Ubiquitin-activating enzyme E1, C-terminal [IPR018965]", "Ubiquitin-activating enzyme E1, FCCH domain [IPR032418]", "Ubiquitin-activating enzyme E1, four-helix bundle [IPR032420]", "Ubiquitin-activating enzyme, SCCH domain [IPR019572]", "Ubiquitin-associated domain [IPR015940]", "Ubiquitin-conjugating enzyme E2 [IPR000608]", "Ubiquitin-like domain [IPR000626]", "Ubiquitin-like domain, USP-type [IPR028135]", "Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain [IPR032353]", "Ubiquitin-specific peptidase 48 [IPR033841]", "Ubiquitin-specific-processing protease 48, Ubl domain [IPR044743]", "Ubiquitin/SUMO-activating enzyme ubiquitin-like domain [IPR028077]", "Ubiquitinyl hydrolase, variant UBP zinc finger [IPR041432]", "Ubiquitinyl hydrolase-L5 [IPR033837]", "Ulp1 protease family, C-terminal catalytic domain [IPR003653]", "Uncharacterised domain CHP00451 [IPR004521]", "Uncharacterised domain NUC130/133, N-terminal [IPR012977]", "Uncharacterised domain NUC173 [IPR012978]", "Uncharacterised domain NUC202 [IPR012980]", "Up-frameshift suppressor 2, C-terminal [IPR007193]", "Upstream-binding protein 1, SAM domain [IPR037600]", "Uroporphyrinogen decarboxylase (URO-D) [IPR000257]", "Uso1/p115-like vesicle tethering protein, C-terminal [IPR006955]", "VASP tetramerisation [IPR014885]", "VHS domain [IPR002014]", "VIP36, lectin domain [IPR035664]", "VPS10 [IPR006581]", "VPS13, repeated coiled region [IPR031642]", "VPS9 domain [IPR003123]", "Vacuolar protein 14, C-terminal Fig4-binding domain [IPR021841]", "Vacuolar protein sorting-associated protein 13, C-terminal [IPR031645]", "Vacuolar protein sorting-associated protein 13, SHR-binding domain [IPR009543]", "Vacuolar protein sorting-associated protein 13, second N-terminal domain [IPR031646]", "Vacuolar protein sorting-associated protein 13-like, N-terminal domain [IPR026854]", "Vacuolar protein sorting-associated protein 4, MIT domain [IPR045253]", "Valyl tRNA synthetase, anticodon-binding domain [IPR033705]", "Vertebrate SNX3, PX domain [IPR042137]", "Vertebrate ubiquitin-conjugating enzyme E2 K, UBA domain [IPR042599]", "Vesicle tethering protein Uso1/P115-like , head domain [IPR006953]", "Vesicle transport v-SNARE, N-terminal [IPR007705]", "Vicinal oxygen chelate (VOC) domain [IPR037523]", "Vinculin-binding site-containing domain [IPR015009]", "Virilizer, N-terminal [IPR031801]", "Vitamin B12-dependent methionine synthase, activation domain [IPR004223]", "Vitamin K epoxide reductase [IPR012932]", "Vps4 oligomerisation, C-terminal [IPR015415]", "Vps53-like, N-terminal [IPR007234]", "Vta1, C-terminal [IPR041212]", "Vta1/callose synthase, N-terminal [IPR039431]", "W2 domain [IPR003307]", "WAPL domain [IPR012502]", "WASP family, EVH1 domain [IPR033927]", "WD repeat-containing protein 18, C-terminal domain [IPR026987]", "WGR domain [IPR008893]", "WH1/EVH1 domain [IPR000697]", "WH2 domain [IPR003124]", "WHEP-TRS domain [IPR000738]", "WHIM1 domain [IPR028942]", "WHIM2 domain [IPR028941]", "WIBG, Mago-binding [IPR015362]", "WSTF/Acf1/Cbp146 [IPR013136]", "WW domain [IPR001202]", "WWE domain [IPR004170]", "Wings apart-like protein, C-terminal [IPR022771]", "Wolframin, EF-hand domain [IPR045460]", "Wolframin, OB-fold domain [IPR045461]", "Wolframin, cysteine-rich domain [IPR045400]", "XPC-binding domain [IPR015360]", "XPG, N-terminal [IPR006085]", "XPG-I domain [IPR006086]", "XRCC1, first (central) BRCT domain [IPR045080]", "XRN2-binding (XTBD) domain [IPR021859]", "Xrn1, helical domain [IPR041412]", "YKT6, SNARE motif [IPR045848]", "YTH domain [IPR007275]", "YchF, C-terminal domain [IPR013029]", "YchF, N-terminal [IPR041706]", "YegS/DAGK, C-terminal domain [IPR045540]", "Yip1 domain [IPR006977]", "YjeF N-terminal domain [IPR004443]", "YqgF/RNase H-like domain [IPR006641]", "YrdC-like domain [IPR006070]", "Z-binding domain [IPR042371]", "ZAP, helix turn helix N-terminal domain [IPR041360]", "ZAP, zinc finger [IPR040954]", "ZC3H15/TMA46 family, C-terminal [IPR032378]", "ZCRB1, RNA recognition motif [IPR034219]", "ZMYND8/11, PWWP domain [IPR035505]", "ZN598/Hel2, RING finger [IPR041888]", "ZN622/Rei1/Reh1, zinc finger C2H2-type [IPR041661]", "ZO-1, SH3 domain [IPR035597]", "ZO-2, SH3 domain [IPR035598]", "ZU5 domain [IPR000906]", "Zasp-like motif [IPR006643]", "Zinc finger C2H2 AKAP95-type [IPR034736]", "Zinc finger C2H2-type [IPR013087]", "Zinc finger, A20-type [IPR002653]", "Zinc finger, B-box, chordata [IPR020457]", "Zinc finger, C2H2, LYAR-type [IPR014898]", "Zinc finger, C3HC-like [IPR012935]", "Zinc finger, C3HC4 RING-type [IPR018957]", "Zinc finger, CCCH-type [IPR000571]", "Zinc finger, CCHC-type [IPR001878]", "Zinc finger, CHCC-type [IPR019401]", "Zinc finger, CHHC-type [IPR012996]", "Zinc finger, CW-type [IPR011124]", "Zinc finger, CXXC-type [IPR002857]", "Zinc finger, ClpX C4-type [IPR010603]", "Zinc finger, DNA-directed DNA polymerase, family B, alpha [IPR015088]", "Zinc finger, FPG/IleRS-type [IPR010663]", "Zinc finger, FYVE-related [IPR017455]", "Zinc finger, GATA-type [IPR000679]", "Zinc finger, GRF-type [IPR010666]", "Zinc finger, LIM-type [IPR001781]", "Zinc finger, MIZ-type [IPR004181]", "Zinc finger, MYM-type [IPR010507]", "Zinc finger, MYND-type [IPR002893]", "Zinc finger, Mcm10/DnaG-type [IPR015408]", "Zinc finger, PARP-type [IPR001510]", "Zinc finger, PHD-finger [IPR019787]", "Zinc finger, PHD-type [IPR001965]", "Zinc finger, RING-CH-type [IPR011016]", "Zinc finger, RING-type [IPR001841]", "Zinc finger, RanBP2-type [IPR001876]", "Zinc finger, SWIM-type [IPR007527]", "Zinc finger, Sec23/Sec24-type [IPR006895]", "Zinc finger, TFIIB-type [IPR013137]", "Zinc finger, TFIIS-type [IPR001222]", "Zinc finger, UBP-type [IPR001607]", "Zinc finger, UBR-type [IPR003126]", "Zinc finger, ZPR1-type [IPR004457]", "Zinc finger, ZZ-type [IPR000433]", "Zinc finger, double-stranded RNA binding [IPR022755]", "Zinc knuckle CX2CX3GHX4C [IPR025829]", "Zinc ribbon, NADH pyrophosphatase [IPR015376]", "Zinc-finger CCCH domain [IPR041686]", "Zinc-finger domain of monoamine-oxidase A repressor R1 [IPR018866]", "Zn-dependent metallo-hydrolase, RNA specificity domain [IPR011108]", "bMERB domain [IPR022735]", "cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain [IPR003117]", "cDENN domain [IPR001194]", "cGMP-dependent protein kinase, interacting domain [IPR031775]", "dDENN domain [IPR005112]", "dUTPase, trimeric [IPR033704]", "dUTPase-like [IPR029054]", "eIF3 subunit M, C-terminal helix domain [IPR040750]", "eIF3B, RNA recognition motif [IPR034363]", "eIF3G, RNA recognition motif [IPR034240]", "eIF3h, C-terminal [IPR045810]", "eIF4H, RNA recognition motif [IPR034229]", "eRF1 domain 1/Pelota-like [IPR005140]", "eRF1 domain 2 [IPR005141]", "eRF1 domain 3 [IPR005142]", "hnRNP A0, RNA recognition motif 1 [IPR034801]", "hnRNP A1, RNA recognition motif 1 [IPR034845]", "hnRNP A1, RNA recognition motif 2 [IPR034803]", "hnRNP A2/B1, RNA recognition motif 1 [IPR034486]", "hnRNP A3, RNA recognition motif 1 [IPR034513]", "hnRNP A3, RNA recognition motif 2 [IPR034516]", "hnRNP DL, RNA recognition motif 1 [IPR034847]", "hnRNP-L, RNA recognition motif 1 [IPR035005]", "hnRNP-L, RNA recognition motif 2 [IPR035008]", "hnRNP-L, RNA recognition motif 3 [IPR034816]", "hnRNP-L, RNA recognition motif 4 [IPR034817]", "hnRNPAB, RNA recognition motif 1 [IPR034846]", "hnRNPH3, RNA recognition motif 2 [IPR034970]", "hnRNPH3, RNA recognition motif 3 [IPR034969]", "hnRNPM, RNA recognition motif 3 [IPR034990]", "hnRPLL, RNA recognition motif 1 [IPR034985]", "hnRPLL, RNA recognition motif 2 [IPR034986]", "hnRPLL, RNA recognition motif 3 [IPR034983]", "hnRPLL, RNA recognition motif 4 [IPR034987]", "mRNA decapping enzyme 2 , NUDIX hydrolase domain [IPR044099]", "mRNA decapping protein 2, Box A domain [IPR007722]", "mRNA decay factor PAT1 domain [IPR019167]", "mRNA splicing factor Cwf21 domain [IPR013170]", "mRNA-decapping enzyme, C-terminal [IPR031953]", "p21 activated kinase binding domain [IPR033923]", "p21-activated kinase 2, catalytic domain [IPR035064]", "p53 transactivation domain [IPR013872]", "p53, DNA-binding domain [IPR011615]", "p53, tetramerisation domain [IPR010991]", "p54nrb, RNA recognition motif 1 [IPR034552]", "rRNA-processing arch domain [IPR025696]", "snRNP70, RNA recognition motif [IPR034143]", "tRNA methyltransferase TRM10-type domain [IPR028564]", "tRNA methyltransferase TRMD/TRM10-type domain [IPR016009]", "tRNA pseudouridylate synthase B, C-terminal [IPR032819]", "tRNA synthetase, B5-domain [IPR005147]", "tRNA synthetases class I, catalytic domain [IPR032678]", "tRNA(Met) cytidine acetyltransferase TmcA, N-terminal [IPR013562]", "tRNA-binding domain [IPR002547]", "tRNA-guanine(15) transglycosylase-like [IPR002616]", "tRNAHis guanylyltransferase catalytic domain [IPR024956]", "tRNase Z endonuclease [IPR027794]", "uDENN domain [IPR005113]", "v-SNARE, coiled-coil homology domain [IPR042855]", "von Willebrand factor, type A [IPR002035]"], "available_proteins": ["AACS", "AAK1", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD11", "ABHD12", "ABHD14B", "ABHD6", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACP1", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTN1", "ACTN2", "ACTN4", "ADA", "ADAM17", "ADAR", "ADD1", "ADD3", "ADH5", "ADK", "ADNP", "ADRM1", "ADSL", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKT1", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALG13", "ALG5", "ALKBH1", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC2", "ANAPC5", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANP32B", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APC", "APEH", "APEX1", "APMAP", "APOBEC3C", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP3", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGAP35", "ARHGAP5", "ARHGEF2", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6", "ARL8B", "ARMC10", "ARMC9", "ARMCX3", "ARMT1", "ASAH1", "ASB6", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATE1", "ATF7IP", "ATIC", "ATL2", "ATL3", "ATP13A1", "ATP13A2", "ATP1A1", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "ATP6V1H", "ATRX", "ATXN10", "ATXN2", "ATXN2L", "AUP1", "B4GALT1", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAZ1A", "BAZ1B", "BCAP31", "BCOR", "BCS1L", "BIRC6", "BLM", "BLVRA", "BLVRB", "BMS1", "BOP1", "BPTF", "BRAP", "BRCA1", "BRD2", "BRD4", "BRIX1", "BROX", "BSG", "BTF3", "BUB1", "BUB1B", "BUD23", "BZW1", "BZW2", "C1orf35", "C2CD5", "CACTIN", "CACUL1", "CACYBP", "CAD", "CADM1", "CALM3", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CAP1", "CAP2", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CARHSP1", "CARM1", "CARS", "CASK", "CASP2", "CASP3", "CBL", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC88A", "CCDC93", "CCDC97", "CCNA2", "CCNB1", "CD2AP", "CD2BP2", "CD47", "CDC23", "CDC25C", "CDC37", "CDC42", "CDC42BPB", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDK1", "CDK11B", "CDK4", "CDK5", "CDK5RAP1", "CDK6", "CDKAL1", "CDKN2AIP", "CDX2", "CEBPZ", "CECR2", "CELF1", "CENPB", "CENPE", "CENPV", "CEP170", "CEP44", "CEP55", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD4", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHORDC1", "CHP1", "CHRAC1", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIRBP", "CISD2", "CIZ1", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLIC1", "CLIC4", "CLINT1", "CLPB", "CLPX", "CLTC", "CLU", "CLUH", "CMBL", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNOT1", "CNOT3", "CNPY2", "COA3", "COASY", "COG2", "COG4", "COIL", "COLEC12", "COMMD1", "COMMD10", "COMMD2", "COMMD7", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "CORO1B", "CORO1C", "COTL1", "COX2", "COX6C", "CPD", "CPNE1", "CPNE3", "CPPED1", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRK", "CRKL", "CRYZ", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTDSPL2", "CTNNBL1", "CTPS1", "CTPS2", "CTSB", "CTSC", "CTTN", "CTTNBP2NL", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC22", "CWF19L1", "CYB5B", "CYB5D2", "CYB5R3", "CYFIP1", "CYFIP2", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCP1A", "DCP1B", "DCP2", "DCTD", "DCTN1", "DCUN1D5", "DDA1", "DDB1", "DDI2", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENND4C", "DENR", "DFFA", "DGCR8", "DHCR24", "DHFR", "DHODH", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIMT1", "DIP2B", "DIS3", "DIS3L2", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNTTIP2", "DOCK7", "DOLPP1", "DPF2", "DPH5", "DPM1", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC2H1", "EARS2", "EBP", "ECE1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFL1", "EFTUD2", "EGFR", "EGLN1", "EHBP1", "EHD1", "EHD4", "EHMT2", "EIF2A", "EIF2AK2", "EIF2AK4", "EIF2B3", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELL", "ELOA", "ELOB", "ELOC", "EMC1", "EMC8", "EMD", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L5", "EPHX1", "EPHX2", "EPN1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERI1", "ERLIN1", "ERLIN2", "ERMP1", "ERP29", "ERP44", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC4", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXTL3", "EZR", "F11R", "FABP5", "FAF1", "FAF2", "FAH", "FAHD1", "FAM118B", "FAM160A2", "FAM208A", "FAM49B", "FAM83D", "FANCA", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FBXO22", "FDFT1", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNBP4", "FNDC3A", "FOXRED1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GAK", "GALK1", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLM", "GCN1", "GDAP1", "GDAP2", "GDPD1", "GEMIN5", "GFM1", "GFPT1", "GGA1", "GGCT", "GGCX", "GHITM", "GID8", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNE", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGB1", "GOPC", "GORASP2", "GOT1", "GOT2", "GPAM", "GPATCH4", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR89B", "GPS1", "GPT2", "GRB2", "GRHPR", "GRSF1", "GRWD1", "GSDME", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F2", "GTF3C1", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTSE1", "GUSB", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAGH", "HARS2", "HAT1", "HAUS3", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDGFL2", "HDLBP", "HEATR1", "HEATR6", "HECTD1", "HELLS", "HERC4", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIP1", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HMBS", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGXB4", "HMMR", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOXD13", "HP1BP3", "HPRT1", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA4", "HSPA4L", "HSPB1", "HSPBP1", "HSPH1", "HTATSF1", "HUWE1", "IARS", "IARS2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFNGR1", "IFT27", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBKB", "IKBKG", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS11", "INTS12", "INTS14", "INTS3", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRGQ", "IRS4", "ISCU", "ISG20L2", "ISOC1", "ISOC2", "ISYNA1", "ITCH", "ITGB1", "ITSN2", "IVD", "IWS1", "JMJD6", "KARS", "KAT7", "KCTD12", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0391", "KIAA1211", "KIAA1468", "KIF11", "KIF14", "KIF15", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIFC1", "KIN", "KMT2A", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "L2HGDH", "LACTB", "LAMB1", "LAMC1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LBR", "LDHA", "LDHB", "LDLR", "LDLRAP1", "LEMD2", "LEMD3", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRCH2", "LRP1", "LRPAP1", "LRPPRC", "LRRC47", "LSM12", "LSM14A", "LSM14B", "LSM2", "LSM6", "LSS", "LTA4H", "LTN1", "LYAR", "LYPLA1", "LYPLAL1", "LZIC", "M6PR", "MACF1", "MAGED1", "MAGED2", "MAK16", "MAN2A1", "MAN2B1", "MANF", "MAP2K1", "MAP2K3", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARK1", "MARK2", "MARS", "MAT2A", "MAT2B", "MATR3", "MAVS", "MCCC1", "MCCC2", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MED1", "MEPCE", "METAP1", "METAP2", "METTL13", "MFAP1", "MFF", "MFN1", "MFN2", "MFSD10", "MGME1", "MIA2", "MIA3", "MICALL1", "MICU1", "MICU2", "MID1", "MINDY3", "MIPEP", "MKI67", "MKLN1", "MKRN2", "MLEC", "MMAB", "MMS19", "MOGS", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MRC2", "MRE11", "MRPL11", "MRPL12", "MRPL15", "MRPL16", "MRPL2", "MRPL39", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL58", "MRPL9", "MRPS10", "MRPS23", "MRPS25", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR2", "MTOR", "MTPAP", "MTR", "MTSS1L", "MTX1", "MTX2", "MTX3", "MUT", "MVK", "MYCBP2", "MYEF2", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA40", "NAA50", "NACC1", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG", "NCAPH2", "NCBP1", "NCL", "NCLN", "NCOR1", "NCSTN", "ND5", "NDC80", "NDUFA10", "NDUFA6", "NDUFA8", "NDUFA9", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEFL", "NEFM", "NEK9", "NELFA", "NELFE", "NEMF", "NENF", "NES", "NFATC2IP", "NFKB1", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NMD3", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOB1", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP2", "NOP56", "NOP58", "NOSIP", "NOVA1", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSUN2", "NSUN5", "NSUN6", "NTPCR", "NUB1", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT16", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP35", "NUP50", "NUP54", "NUP62", "NUP98", "NUPL2", "NVL", "NXF1", "NXN", "OCIAD1", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1", "PAK2", "PAK4", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PATL1", "PAXIP1", "PBDC1", "PBK", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCM1", "PCNA", "PCNT", "PCYOX1", "PDAP1", "PDCD11", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDPR", "PDXK", "PDZD8", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PFAS", "PFKL", "PFKM", "PFKP", "PGD", "PGLS", "PGM1", "PGM2", "PGM3", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF2", "PHF3", "PHF6", "PHF8", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGG", "PIH1D1", "PIK3C2A", "PIK3C3", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2B", "PIR", "PITHD1", "PITRM1", "PKM", "PKN1", "PKN2", "PLAA", "PLCB3", "PLCG1", "PLD3", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMS1", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPO", "PNPT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR3A", "POLR3C", "POLRMT", "POP1", "POR", "PPAN", "PPAT", "PPFIA1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP3CA", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPWD1", "PQBP1", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREP", "PREPL", "PRKAA1", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKAR2B", "PRKCD", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPN1", "PTPN11", "PTPN23", "PTPN9", "PTPRF", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PWP2", "PYCR1", "PYCR2", "PYM1", "QARS", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABEP1", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAPGEF2", "RAPGEF6", "RARS", "RARS2", "RAVER1", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM47", "RBM5", "RBM8A", "RBMX", "RBPMS", "RCL1", "RCN1", "RCN2", "RDX", "RECQL", "RECQL4", "RECQL5", "REPS1", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIF1", "RIOX1", "RIOX2", "RIPK1", "RMND5A", "RNASEH2A", "RNASEH2B", "RNF14", "RNF20", "RNF219", "RNF220", "RNF40", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL11", "RPL12", "RPL14", "RPL18", "RPL18A", "RPL19", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL30", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPP25L", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS2", "RPS20", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS9", "RPSA", "RPTOR", "RPUSD2", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRP12", "RSF1", "RSL24D1", "RTCA", "RTF1", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SACS", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART3", "SASS6", "SBDS", "SBNO1", "SCAF11", "SCAF4", "SCCPDH", "SCML2", "SCO2", "SCP2", "SCRIB", "SCYL2", "SDAD1", "SDCBP", "SDF2L1", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEL1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SETD7", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGTA", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SIN3A", "SIRT1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC18B1", "SLC25A12", "SLC25A13", "SLC25A24", "SLC27A4", "SLC38A2", "SLC3A2", "SLC4A1AP", "SLC6A15", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SLU7", "SMAP1", "SMAP2", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMS", "SMU1", "SNAP23", "SNAP29", "SND1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC25", "SPECC1", "SPECC1L", "SPEN", "SPHK2", "SPNS1", "SPPL2A", "SPRYD4", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRBD1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STIP1", "STK26", "STK4", "STOM", "STOML2", "STRBP", "STRN", "STUB1", "STX12", "STX18", "STX4", "STX6", "STX7", "STX8", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE1", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACC3", "TAF15", "TAGLN2", "TANGO6", "TAP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D17", "TBC1D2B", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCB", "TBCC", "TBCD", "TBCE", "TBK1", "TBL1XR1", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TDRD7", "TDRKH", "TECR", "TELO2", "TERF2", "TERF2IP", "TES", "TEX10", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "THG1L", "THOC1", "THOC2", "THOC3", "THOP1", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIMELESS", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TIMM9", "TJP1", "TJP2", "TKFC", "TKT", "TLN1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM201", "TMEM205", "TMEM63A", "TMEM97", "TMF1", "TMLHE", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOM1", "TOP1", "TOP2A", "TOP2B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIO", "TRIP12", "TRIP13", "TRMT1", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TROVE2", "TRUB1", "TSC2", "TSFM", "TSG101", "TSR1", "TTC28", "TTC4", "TTF2", "TTK", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXN2", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAP2", "UBAP2L", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE2T", "UBE3A", "UBE3C", "UBE4A", "UBL5", "UBLCP1", "UBP1", "UBQLN1", "UBQLN2", "UBQLN4", "UBR1", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UGDH", "UGGT1", "UHRF1", "UHRF1BP1", "UMPS", "UNC119B", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCRC1", "UQCRC2", "UQCRFS1", "URB1", "UROD", "USO1", "USP10", "USP11", "USP14", "USP15", "USP24", "USP28", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP20", "UTRN", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VCP", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VPS13A", "VPS18", "VPS29", "VPS37C", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK2", "VTA1", "VTI1B", "WAPL", "WARS", "WASL", "WBP2", "WDHD1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR36", "WDR43", "WDR46", "WFS1", "WIZ", "WNK1", "WNK2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YAP1", "YARS", "YBX1", "YBX3", "YIPF4", "YKT6", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF1", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM2", "ZMYM4", "ZMYND8", "ZNF24", "ZNF281", "ZNF318", "ZNF326", "ZNF512B", "ZNF598", "ZNF622", "ZNF638", "ZPR1", "ZRANB2", "ZSWIM8", "ZYX"], "leading_proteins": ["ACOT7", "ACTN1", "ACTN4", "AKAP8", "ALG5", "ALKBH5", "ALYREF", "ANKLE2", "ARMC10", "ARMT1", "ASCC2", "ASCC3", "ATAD3B", "ATP13A1", "ATP13A2", "ATP1A1", "ATP2A2", "ATXN2", "ATXN2L", "AUP1", "BAG4", "BAG5", "BAIAP2", "BSG", "BUB1B", "CACYBP", "CALM3", "CALU", "CBX3", "CBX5", "CD2BP2", "CDC42BPB", "CDKAL1", "CERS2", "CIRBP", "CRK", "CSRP2", "CTPS1", "CTSB", "CYB5B", "CYFIP1", "DLD", "DNA2", "DNAJA1", "DNAJA2", "DNM1L", "DPM1", "DUSP9", "EFCAB14", "EIF4B", "EIF4H", "ERAP1", "ERLIN1", "ERLIN2", "ERMP1", "EWSR1", "EXOSC2", "EXOSC5", "EXOSC7", "EXOSC8", "FAM49B", "FASN", "FHL1", "FKBP10", "FKBP14", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP7", "FLOT1", "FMR1", "FUBP1", "FUBP3", "FUCA2", "FUS", "FXR1", "FXR2", "GAA", "GALNT1", "GALNT2", "GFPT1", "GID8", "GINS4", "GM2A", "GMPPA", "GMPPB", "GNPAT", "GPAM", "GRB2", "GSTA4", "HACD3", "HDGF", "HK2", "HLA-A", "HLA-C", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPR", "HNRNPUL1", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "IDH2", "IGF2R", "ILF3", "IMPDH2", "IPO7", "IPO8", "KDM1B", "KHDRBS3", "KHSRP", "KIF1B", "LASP1", "LIMA1", "LMAN1", "LNPEP", "M6PR", "MAPRE2", "MICALL1", "MIPEP", "MPP2", "MPP6", "MPST", "MRC2", "MRPL45", "MSI1", "MTX1", "MTX2", "NCLN", "NECAP2", "NEFL", "NENF", "NISCH", "NLN", "NOL10", "NPEPPS", "NPTN", "NSD2", "NUCB1", "NUCB2", "NUDCD1", "NUDCD3", "OPA1", "P3H1", "P4HA1", "PABPC1", "PABPC4", "PAIP1", "PAIP2", "PAK1", "PAK2", "PARN", "PCNT", "PDCD6", "PDLIM3", "PDLIM5", "PDLIM7", "PDPR", "PGM3", "PGRMC2", "PHB", "PHB2", "PI4KA", "PNPT1", "POGZ", "POLE4", "POLR1C", "POLR2B", "PPP1R10", "PRDX3", "PREP", "PREPL", "PRKAA2", "PRRC2A", "PRRC2B", "PSMA1", "PTBP2", "PTGES3", "PTPRF", "PUF60", "RAVER1", "RBM10", "RBM14", "RBM15B", "RBM3", "RBM4", "RBM47", "RBMX", "RBPMS", "RCN2", "REPS1", "RHOT1", "RIOX1", "RMND5A", "RNF14", "RTN1", "SEC22B", "SEC23IP", "SEC63", "SHMT1", "SLC18B1", "SMARCAD1", "SMNDC1", "SNAP29", "SNX12", "SNX27", "SPHK2", "SPPL2A", "SPTAN1", "SRSF1", "SRSF6", "SRSF9", "STAM", "STAMBP", "STOM", "STOML2", "STRBP", "STX12", "STX6", "STX7", "SUN1", "SUPT6H", "SYNCRIP", "TAF15", "TAP1", "TARDBP", "TBC1D10A", "TBC1D15", "TBC1D4", "TBC1D8B", "TBC1D9B", "TCEA1", "TDRKH", "TES", "TIAL1", "TIMM8A", "TIMM8B", "TMED2", "TMEM97", "TMPO", "TNPO1", "TPBG", "TRA2B", "TRAM1", "TRIM21", "TRMT2A", "TXNRD1", "U2AF1", "U2AF2", "UBP1", "UBR1", "UBR5", "UNC119B", "VIM", "WBP2", "XPO5", "YBX3", "YKT6", "YTHDC2", "YTHDF2", "YTHDF3", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZCCHC3", "ZCRB1", "ZFR", "ZNF326", "ZYX"]} \ No newline at end of file diff --git a/interpro_family/advanced/idx2term.json b/interpro_family/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..f6bd5b9f0e60fef9063a9b06df6e43814a13f72a --- /dev/null +++ b/interpro_family/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Proteasome, subunit alpha/beta [IPR001353]"} \ No newline at end of file diff --git a/interpro_family/advanced/plot_0.png b/interpro_family/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..24023c22f6e1c94e47af613aace976d6df89a637 --- /dev/null +++ b/interpro_family/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bc24e80f7c05f3b0805a07b0addc24dec705414cb72a920b79d95b85cc8cf896 +size 190057 diff --git a/interpro_family/basic/idx2term.json b/interpro_family/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..b0f9f98635c1889709323e216140bd60da2049c6 --- /dev/null +++ b/interpro_family/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Proteasome, subunit alpha/beta [IPR001353]", "1": "14-3-3 protein [IPR000308]", "2": "Small GTPase Rho [IPR003578]"} \ No newline at end of file diff --git a/interpro_family/basic/plot_0.png b/interpro_family/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..f536fa5914e21d3b47027ea57a426c5998e96923 --- /dev/null +++ b/interpro_family/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:390505a90fdc1282e7dbdbd7d895a87980b813b3858ab067d64e7d12c4afe8c4 +size 145855 diff --git a/interpro_family/basic/plot_1.png b/interpro_family/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..212484d9e68a72beff0a5410303d633440b8b5d9 --- /dev/null +++ b/interpro_family/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:559d718c5b2c9c84efa00bdfe9cb75a493f8a6369bac34ea184840452bae9281 +size 130986 diff --git a/interpro_family/basic/plot_2.png b/interpro_family/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..acf19e3908e03998150e72b11c7e9a1d1935d6a0 --- /dev/null +++ b/interpro_family/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:980aa803599de2c4bc82224ae8028692e329e4f7ced8e9226bf6c7913aa168b8 +size 137491 diff --git a/interpro_family/consensus.joblib b/interpro_family/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..e84efe5426bc3b6a524f952abf97c2499cbc624b --- /dev/null +++ b/interpro_family/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:889c28e8f3c8c5794f25720fa1f5da6efab1cc58b14e1c9391ad480fbb705148 +size 421376 diff --git a/interpro_family/df_merge.tsv b/interpro_family/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..0a8ce6278fde5c7797b8ceec78a44f03142a3e77 --- /dev/null +++ b/interpro_family/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Proteasome, subunit alpha/beta [IPR001353] 6 14 2.6400764426515355 0.008288732890141 5.075242718446602 13.970873786407768 1.2284854682369022 0.3020132543529001 2.3027355385508845 0.1681602725795027 1.1101966392985694 0.3179790146746512 0.0069592764782258 1.0 0.0102498345034834 2.867880480409346e-05 4.949573022786166e-06 +Proteasome B-type subunit [IPR023333] 4 7 2.399641601636236 0.0164111310806109 3.699029126213592 6.970873786407767 1.6670727234653664 0.1509307531330224 1.4503762582219135 0.1681602725795027 0.9611878160538336 0.233503072382129 0.0021644162661245 1.0 0.0032139762811053 9.515842072742196e-07 2.915330495677531e-05 diff --git a/interpro_family/metrics.json b/interpro_family/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..1cf2ae99f84ec7b7ea6ec9a32af4aed373f1f789 --- /dev/null +++ b/interpro_family/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3329, + "annotations_size": 2534, + "title": "Average number of proteins per term", + "value": 1.2896606156274664 +} \ No newline at end of file diff --git a/interpro_family/paths.json b/interpro_family/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..859b96d5fb1252ec12f2d1c03fbbf6e512083f02 --- /dev/null +++ b/interpro_family/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_family/fragment/C342/C342_val_log2fc"} \ No newline at end of file diff --git a/interpro_family/result.tsv b/interpro_family/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..e2739250a0a5c66d3a84554dba020e3170a79275 --- /dev/null +++ b/interpro_family/result.tsv @@ -0,0 +1,129 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Proteasome, subunit alpha/beta [IPR001353] 0.7721679951014658 2.6400764426515355 0.008288732890141 0.9999999993078234 0.0648850863399621 14 P28070,P25786,P20618,P28074,P49721,P28072 6 +Proteasome B-type subunit [IPR023333] 0.8941095666428472 2.399641601636236 0.0164111310806109 1.0 0.0820379858526385 7 P49721,P28070,P28074,P28072 4 +Mpv17/PMP22 [IPR007248] 0.9915840096182744 1.9173214763766695 0.0551971031611886 1.0 0.1625285669235246 2 Q9NR77 1 +ER lumen protein retaining receptor [IPR000133] 0.9912834385332128 1.916102319709869 0.0553520731077354 1.0 0.1625285669235246 2 O43731 1 +Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930] 0.8469948171244304 1.897298412488972 0.0577885644030908 1.0 0.1664166718644242 5 P55786,Q9UIQ6,Q9NZ08 3 +Haem oxygenase [IPR002051] 0.9843703035767944 1.8880400209766384 0.0590205778978827 1.0 0.1674783251883928 2 P30519 1 +Haem oxygenase-like [IPR016053] 0.9843703035767944 1.8880400209766384 0.0590205778978827 1.0 0.1674783251883928 2 P30519 1 +Nucleobindin [IPR040250] 0.9783588818755626 1.8636051957776056 0.0623771674745212 1.0 0.1731256762107742 2 P80303 1 +Isocitrate dehydrogenase NADP-dependent [IPR004790] 0.9771565975353153 1.8587146864789037 0.0630675906225466 1.0 0.1736753452646054 2 P48735 1 +CD36 family [IPR002159] 0.9528103396453212 1.7594486776900002 0.0785013301358206 1.0 0.196952842142742 2 Q8WTV0 1 +ATPase, V0 complex, subunit 116kDa, eukaryotic [IPR026028] 0.9510069131349568 1.752079445630826 0.0797601480816372 1.0 0.1977735746542875 2 Q9Y487 1 +V-type ATPase, V0 complex, 116kDa subunit family [IPR002490] 0.9510069131349568 1.752079445630826 0.0797601480816372 1.0 0.1977735746542875 2 Q9Y487 1 +Eukaryotic porin/Tom40 [IPR027246] 0.9049166997075976 1.7496222942000552 0.0801835101580956 1.0 0.1980360767452382 4 P21796 1 +Palmitoyl protein thioesterase [IPR002472] 0.9474000601142164 1.7373349961942035 0.0823280577810419 1.0 0.2015645395334881 2 P50897 1 +Pyrimidine 5'-nucleotidase, eukaryotic [IPR006434] 0.946498346859026 1.7336476706796489 0.082980616668673 1.0 0.2022369172772085 2 Q969T7 1 +Basigin-like [IPR043204] 0.9332732191163168 1.6795156964680216 0.093051582360905 1.0 0.2165222311318029 2 Q9Y639 1 +Transmembrane protein GPR107/GPR108-like [IPR009637] 0.9765484064942864 1.6720041155539116 0.0945235105264452 1.0 0.2183432777338307 3 Q9NPR9,Q8NBN3 2 +Ergosterol biosynthesis ERG4/ERG24 [IPR001171] 0.9296663660955744 1.664737341611549 0.0959651695802898 1.0 0.2204675790720349 2 Q14739 1 +Peptidase S10, serine carboxypeptidase [IPR001563] 0.9738424533974744 1.661986942064216 0.0965153926992665 1.0 0.2211302035261677 3 Q9H3G5,Q9HB40 2 +Prolyl 4-hydroxylase [IPR045054] 0.9242560865644736 1.6425593235928824 0.1004741425719304 1.0 0.2254213295870733 2 P13674 1 +P-type ATPase, subfamily V [IPR006544] 0.9185452359482972 1.619137041622633 0.1054177804661724 1.0 0.2307298680342036 2 Q9HD20 1 +Serine hydroxymethyltransferase [IPR001085] 0.91794409377818 1.6166708858695076 0.1059493416365748 1.0 0.2310975703317412 2 P34896 1 +Peptidase S9A, prolyl oligopeptidase [IPR002470] 0.908926961226326 1.579665935706802 0.1141833905981832 1.0 0.242787255187663 2 P48147 1 +Porin, eukaryotic type [IPR001925] 0.9371486523604724 1.525808329059892 0.1270576057990111 1.0 0.2600678296403023 3 P21796 1 +ADP-ribosylation factor 1-5 [IPR045872] 0.8957018334836195 1.5253615541403416 0.1271689424923443 1.0 0.260085633797902 2 P18085 1 +P-type ATPase [IPR001757] 0.7539943771241531 1.5218790146467065 0.1280393982865071 1.0 0.2614438640274045 5 Q9NQ11,Q9HD20 2 +TAF15/EWS/TLS family [IPR034870] 0.930246542393262 1.5001391729395044 0.1335783556115182 1.0 0.2675790933751676 3 Q92804,P35637 2 +Aminopeptidase N-type [IPR034016] 0.927841250751648 1.4911912070740985 0.1359113015556599 1.0 0.2701170495231703 3 Q9UIQ6,Q9NZ08 2 +Mitochondrial carrier UCP-like [IPR002030] 0.8824767057408968 1.4710454837045976 0.1412788167548591 1.0 0.2763334765444439 2 Q9H2D1 1 +CTP synthase [IPR004468] 0.8761647129546055 1.445126478636242 0.1484223627154777 1.0 0.284925959940167 2 P17812 1 +Sulfotransferase [IPR005331] 0.8716561466786799 1.426617432998833 0.153690196500853 1.0 0.2928202691226779 2 Q8NCH0 1 +HnRNP R/Q splicing factor [IPR006535] 0.9073962717979528 1.4151004510714766 0.1570390459773973 1.0 0.2967464149938292 3 A0AV96,O60506 2 +Transmembrane emp24 domain-containing protein [IPR015720] 0.7242210697770017 1.3996855883222057 0.1616074913181657 1.0 0.3008915378399941 5 Q15363 1 +Prenyltransferase subunit beta [IPR045089] 0.8962717979554964 1.3736932550204612 0.1695369317619155 1.0 0.311083696657997 3 P53609,P49356 2 +UBAP2/protein lingerer [IPR022166] 0.8551247370003011 1.3588071404635358 0.1742077100611205 1.0 0.3166731257495548 2 Q5T6F2 1 +Nucleosome assembly protein (NAP) [IPR002164] 0.7996030031393077 1.344671486974774 0.1787313463999762 1.0 0.3214373539939956 4 Q01105,Q99733 2 +Cleft lip and palate transmembrane protein 1-like protein [IPR030434] 0.8470093177036382 1.3255664959848046 0.1849833300459682 1.0 0.328484764076022 2 O96005 1 +Cleft lip and palate transmembrane 1 [IPR008429] 0.8470093177036382 1.3255664959848046 0.1849833300459682 1.0 0.328484764076022 2 O96005 1 +Class I-like SAM-dependent O-methyltransferase [IPR002935] 0.8458070333633906 1.320645474904572 0.1866196024426778 1.0 0.3299809383230754 2 P21964 1 +Fragile X mental retardation syndrome-related protein [IPR040148] 0.8767288033674043 1.3009993750924018 0.1932586686276542 1.0 0.338202670098395 3 P51116,P51114 2 +YTH domain containing protein [IPR045168] 0.7872547617300262 1.2969086655377058 0.1946626145575281 1.0 0.3399552483037741 4 Q7Z739,Q9Y5A9 2 +Mitotic spindle checkpoint protein Bub1/Mad3 [IPR015661] 0.8325819056206792 1.2665874329268605 0.2053028483290615 1.0 0.3505642976184919 2 O60566 1 +Transmembrane protein 126 [IPR009801] 0.8259693417493124 1.239617721102502 0.2151168229032687 1.0 0.3616451186149598 2 Q9H061 1 +Peptidase T1A, proteasome beta-subunit [IPR000243] 0.86002090444289 1.2389605818235845 0.2153600962864934 1.0 0.3616451186149598 3 P28072 1 +Syntaxin [IPR045242] 0.6815117814845695 1.223513170124743 0.2211359329135813 1.0 0.3681724402122307 5 Q86Y82,O43752,O15400 3 +Methylthiotransferase [IPR005839] 0.8151487826870957 1.1955907587819083 0.2318562994889956 1.0 0.3805206365965771 2 Q5VV42 1 +Tetraspanin/Peripherin [IPR018499] 0.839278149833835 1.1621857678919758 0.2451600144400165 1.0 0.3934360206402799 3 O43657 1 +Cytoplasmic FMR1-interacting [IPR008081] 0.8022242260294545 1.143209237643564 0.2529517277934827 1.0 0.401616339742284 2 Q7L576 1 +A-kinase anchor protein 9/Pericentrin [IPR028745] 0.8016230838593355 1.1407791371563825 0.2539618445951817 1.0 0.4029676356945462 2 O95613 1 +Cytochrome P450 [IPR001128] 0.7965133754132685 1.1201479848586229 0.2626507052963229 1.0 0.4131327667417023 2 Q16850 1 +Polyadenylate binding protein, human types 1, 2, 3, 4 [IPR006515] 0.7902013826269894 1.0947272592094206 0.2736361425707079 1.0 0.4233174513273344 2 P11940 1 +A-kinase anchoring protein 95 (AKAP95) [IPR007071] 0.8205051112447317 1.0930502789867114 0.2743717247889545 1.0 0.424196431125815 3 O43823,Q5BKZ1 2 +SUN domain-containing protein 1-5 [IPR045119] 0.7892996693718056 1.0911019332611975 0.2752280322650224 1.0 0.4247428951032685 2 O94901 1 +Tropomyosin [IPR000533] 0.8177991581479169 1.0831198201959142 0.2787552425551365 1.0 0.4286200149482499 3 P67936,P09493 2 +Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase [IPR022284] 0.7826871055004534 1.064566791975326 0.2870720140885119 1.0 0.4357477486976605 2 O15228 1 +Peptidase M3A/M3B [IPR045090] 0.8126879134094951 1.0643896641822015 0.2871522140605016 1.0 0.4357477486976605 3 Q9BYT8,Q99797 2 +Ribonucleotide reductase small subunit family [IPR000358] 0.780583107905001 1.0561432992818989 0.2909027508669424 1.0 0.438517293692345 2 Q7LG56 1 +Ribonucleotide reductase small subunit [IPR033909] 0.780583107905001 1.0561432992818989 0.2909027508669424 1.0 0.438517293692345 2 Q7LG56 1 +Mitochondrial carrier protein [IPR002067] 0.5261672198038077 1.0376340179091377 0.2994404742338787 1.0 0.446342448063911 10 Q9UJS0,P12235,Q8TBP6,Q6NUK1 4 +Protein arginine N-methyltransferase [IPR025799] 0.632460434135241 1.021335377038309 0.3070955709286584 1.0 0.4541981170320467 5 Q6P2P2,Q86X55 2 +Alpha-L-fucosidase, metazoa-type [IPR016286] 0.7598437030357483 0.9736853915185676 0.3302127728982911 1.0 0.4716793497882016 2 Q9BTY2 1 +Glycoside hydrolase, family 29 [IPR000933] 0.7598437030357483 0.9736853915185676 0.3302127728982911 1.0 0.4716793497882016 2 Q9BTY2 1 +DNA2/NAM7-like helicase [IPR045055] 0.6999096171283062 0.9613659827595432 0.3363681820509372 1.0 0.4772561925526746 4 P51530 1 +Nonaspanin (TM9SF) [IPR004240] 0.7843583753604272 0.9613482493210762 0.3363770954613563 1.0 0.4772561925526746 3 Q9HD45 1 +Molecular chaperone regulator BAG [IPR039773] 0.7790138304269314 0.9420823659718582 0.3461504719695232 1.0 0.4861744948981634 3 O95429,Q9UL15 2 +Short-chain dehydrogenase/reductase SDR [IPR002347] 0.4261303344946401 0.9354851268464998 0.3495383447228495 1.0 0.4882746226723818 20 Q06136,Q3SXM5,P35270 3 +Microtubule-associated protein RP/EB [IPR027328] 0.7388037270814363 0.8913064237680492 0.372764803415448 1.0 0.5081151220305247 2 Q15555 1 +Prefoldin alpha-like [IPR004127] 0.7624239059987326 0.8827069879359436 0.3773946055998971 1.0 0.511169234245195 3 Q9UBK9 1 +Golgi phosphoprotein 3-like [IPR008628] 0.7351968740607159 0.8773367784311041 0.380303741340074 1.0 0.5126008939126317 2 Q9H4A6 1 +Sorting nexin-5/6/32 [IPR014637] 0.7204688908926782 0.8208252861773869 0.411745793248413 1.0 0.5400433954924837 2 Q9Y5X3 1 +Hexokinase [IPR001312] 0.7171626089570039 0.8082651094792781 0.4189379833195228 1.0 0.5460847992446867 2 P52789 1 +TB2/DP1/HVA22-related protein [IPR004345] 0.7385367271355359 0.7985584673616043 0.4245464783062354 1.0 0.5502817268685424 3 Q6NUK4 1 +ADP/ATP carrier protein, eukaryotic type [IPR002113] 0.7384014775101817 0.79808719259806 0.4248198931619078 1.0 0.5503546059674205 3 P12235 1 +Major facilitator superfamily [IPR011701] 0.651155424736652 0.7794294563991248 0.4357267775929241 1.0 0.5596207067513784 4 Q6NT16 1 +Membrane bound O-acyl transferase, MBOAT [IPR004299] 0.7063420498948012 0.7675136216212772 0.4427761974872599 1.0 0.5635366737941963 2 Q96N66 1 +KH domain-containing BBP-like [IPR045071] 0.644125323721025 0.7537818984940552 0.4509801950389511 1.0 0.5696560700662887 4 O75525,Q07666 2 +Kinesin light chain [IPR002151] 0.723090799759462 0.745164326902814 0.4561723854095447 1.0 0.5736987708224561 3 Q07866,Q9H0B6 2 +ATPase family AAA domain-containing protein 3 [IPR039188] 0.7003306281935697 0.7451237197495527 0.4561969310210139 1.0 0.5736987708224561 2 Q5T9A4 1 +Proteasome alpha-type subunit [IPR023332] 0.5048896297438696 0.7087329033403902 0.4784902422247099 1.0 0.5928052617979036 7 P25786 1 +Dynamin [IPR022812] 0.7083583884545824 0.6951163969372178 0.4869823597555294 1.0 0.5990355823400542 3 O00429,O60313 2 +Phosphatidylinositol kinase [IPR015433] 0.6273335116662428 0.6932993625895307 0.4881217029813354 1.0 0.5996978990816951 4 P42356 1 +Type 1 protein exporter [IPR039421] 0.6980078184608244 0.6605315238312908 0.5089127956639072 1.0 0.6159521121387472 3 Q03518 1 +Mitochondrial import inner membrane translocase subunit Tim8/13 [IPR039238] 0.6753832281334546 0.654364866916665 0.5128767636685296 1.0 0.6183562229080287 2 O60220 1 +Tricarboxylate/iron carrier [IPR004686] 0.6955883457698816 0.6525213159260436 0.5140649264432793 1.0 0.6185409652286283 3 Q6P4A7 1 +Small GTPase superfamily, ARF type [IPR024156] 0.539601743769498 0.6496322498791804 0.515929796248455 1.0 0.6197891582194087 5 P18085 1 +E3 ubiquitin ligase Bre1 [IPR013956] 0.6720769461977787 0.6426239918134596 0.5204681115233869 1.0 0.6233372990325375 2 Q5VTR2 1 +Small GTPase superfamily, ARF/SAR type [IPR006689] 0.4439192631885013 0.624303004780541 0.5324286109657586 1.0 0.6304551870033795 10 P36404,P18085,P84085 3 +Erlin1/2 [IPR033294] 0.6612563871355595 0.6047206406151203 0.5453646312035456 1.0 0.6385436125999913 2 O94905 1 +Translin family [IPR002848] 0.6573489630297586 0.5912387555129842 0.5543604587374682 1.0 0.6441094192241773 2 Q15631 1 +Exportin 4/7-like [IPR044189] 0.6402164111812478 0.533516244092894 0.5936762694220803 1.0 0.6698021668368439 2 Q9C0E2 1 +Prefoldin beta-like [IPR002777] 0.569790803769711 0.4969275903497285 0.6192401144063489 1.0 0.6867196717311544 4 O60925 1 +DNA-directed RNA polymerase, subunit 2 [IPR015712] 0.60414788097384 0.4204063293832003 0.6741886451188714 1.0 0.7238957740386527 2 P30876 1 +DnaJ homolog subfamily A member 1/2-like [IPR044713] 0.5972347460174282 0.4001937206473049 0.689013839248307 1.0 0.7348251929974222 2 O60884 1 +Ubiquilin-1/2 [IPR028430] 0.5879170423805267 0.3737677807352701 0.7085770922052026 1.0 0.7483359264157191 2 Q9UMX0 1 +Chaperone DnaJ [IPR012724] 0.5923030667468328 0.3456251747601633 0.7296244239449428 1.0 0.7652600539223862 3 O60884,P31689 2 +14-3-3 protein [IPR000308] 0.4363526933493882 0.3443635797575755 0.7305728749219027 1.0 0.7659378010145228 6 P61981,P27348,P63104,P62258,Q04917 5 +Dynein light chain, type 1/2 [IPR001372] 0.5716862037872026 0.3300877929867153 0.7413336265801576 1.0 0.776898018922299 2 Q96FJ2 1 +Cyclophilin-type peptidyl-prolyl cis-trans isomerase, cyclophilin A-like [IPR044666] 0.5856885147324026 0.3288998861937988 0.742231360336753 1.0 0.777517266264296 3 Q9H2H8,Q96BP3 2 +Exosome complex RNA-binding protein 1/RRP40/RRP4 [IPR026699] 0.5707844905320191 0.3277519657098476 0.7430992086553001 1.0 0.7781047085671614 2 Q13868 1 +SCAMP [IPR007273] 0.5515479410880688 0.2802979956432381 0.7792488884221005 1.0 0.8122651926209802 2 O15127 1 +Ataxin2-like [IPR045117] 0.5422302374511628 0.2589923864702873 0.795641114846213 1.0 0.8266316461747863 2 Q99700 1 +Heterogeneous nuclear ribonucleoprotein C [IPR017347] 0.5380222422603014 0.2497395467220459 0.8027887731465166 1.0 0.8326920798826333 2 P07910 1 +Small GTPase Rho [IPR003578] 0.4050556725850178 0.2432291393935242 0.8078278945734563 1.0 0.837264712237549 6 Q8IXI2,Q8IXI1,P63000,P61586,P84095 5 +Heat shock protein Hsp90 family [IPR001404] 0.4769924812030113 0.2356555207535914 0.8136999871484265 1.0 0.8426300643376022 4 P08238,P14625,P07900 3 +Stomatin/HflK/HflC family [IPR001972] 0.5214908325819031 0.2156510001121868 0.8292597986659032 1.0 0.855944737197311 2 P27105 1 +Eukaryotic translation initiation factor 3 subunit M eIF3m/COP9 signalosome complex subunit 7 COPS7 [IPR045237] 0.5211902614968456 0.2150648826791061 0.8297167328117381 1.0 0.8560676713945213 2 Q7L2H7 1 +Initiation factor 2B-related [IPR000649] 0.5246542393265 0.1958925342929564 0.8446942808335058 1.0 0.8701037835902861 3 Q9UI10,P49770 2 +Inosine-5'-monophosphate dehydrogenase [IPR005990] 0.508265704839207 0.1910077773588506 0.8485194998911771 1.0 0.872625167501722 2 P12268 1 +Oligosaccharyl transferase, STT3 subunit [IPR003674] 0.505861136158702 0.186779413832103 0.8518335882430541 1.0 0.8746135788524713 2 P46977 1 +Small GTPase superfamily, SAR1-type [IPR006687] 0.5022542831379704 0.1805822719002633 0.8566954720731479 1.0 0.8788932494871889 2 Q9NR31 1 +THRAP3/BCLAF1 family [IPR029199] 0.5007514277126627 0.1780515654090707 0.8586824793379182 1.0 0.8798630823462534 2 Q9Y2W1 1 +Prohibitin [IPR000163] 0.4992485722873466 0.1755510733020777 0.860646643116981 1.0 0.8815192375337226 2 P35232 1 +Ribosomal protein S8e/ribosomal biogenesis NSA2 [IPR022309] 0.4893297264803224 0.1598025906729467 0.8730365832484357 1.0 0.893126645923107 2 O95478 1 +Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein [IPR001129] 0.4806131650135326 0.1470356884584743 0.8831038511292864 1.0 0.901969028118344 2 O14880 1 +Mitochondrial Rho GTPase [IPR021181] 0.4676886083558834 0.129915351607464 0.8966333983992543 1.0 0.9150499522930772 2 Q8IXI2 1 +Protein PRRC2 [IPR033184] 0.4780517137702758 0.1223514454766719 0.9026206904108574 1.0 0.9196786608367964 3 Q5JSZ5,P48634 2 +Long-chain fatty acid CoA synthetase, eukaryotic [IPR045311] 0.4496543432521959 0.1095040009568637 0.9128027485498074 1.0 0.928932596315346 2 Q9UKU0 1 +Protein phosphatase 2A, regulatory B subunit, B56 [IPR002554] 0.4364292155094613 0.0969644800190017 0.9227546023271104 1.0 0.937930269673846 2 Q16537 1 +Ribosomal protein L15 [IPR030878] 0.4349263600841528 0.0956626949670118 0.923788470073802 1.0 0.938604644413398 2 Q9P015 1 +Glycoside hydrolase family 31 [IPR000322] 0.4283137962127976 0.0902212948187578 0.9281113625161486 1.0 0.9426189148761204 2 P10253 1 +Flotillin family [IPR027705] 0.4277126540426755 0.0897493482994087 0.9284863998701964 1.0 0.9426220101246304 2 O75955 1 +Actin-related protein 2/3 complex subunit 1 [IPR017383] 0.4039675383228137 0.0739258001528877 0.9410694264607908 1.0 0.9538679706606576 2 O15143 1 +SURP and G-patch domain-containing protein 1/2 [IPR040169] 0.4030658250676261 0.0734263308128838 0.9414668651854996 1.0 0.953889258848483 2 Q8IWZ8 1 +Tropomodulin [IPR004934] 0.3958521190261458 0.0696740025373144 0.9444531344518472 1.0 0.9565324711035096 2 Q9NYL9 1 +Vacuolar protein sorting-associated protein 33 [IPR027121] 0.311091073038763 0.0488647466058581 0.9610270834168432 1.0 0.971454982564884 2 Q96AX1 1 +HnRNP-L/PTB [IPR006536] 0.3536842105263198 0.0449537479890179 0.9641441754133904 1.0 0.973751032482077 4 Q8WVV9,Q9UKA9,P14866 3 +E3 ubiquitin ligase RBR family [IPR031127] 0.3728915062048832 0.038987208700974 0.9689005868388638 1.0 0.9777754229588532 3 Q9UBS8 1 +Pre-mRNA-splicing factor Syf1-like [IPR045075] 0.2892363199037928 0.0237161676116553 0.9810790097438662 1.0 0.9859299796747932 3 O94906,Q9BZJ0 2 diff --git a/interpro_family/selections.json b/interpro_family/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..798319a3057781a9d046669e90b6459728d5b2d9 --- /dev/null +++ b/interpro_family/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["(Uracil-5)-methyltransferase family [IPR010280]", "-alpha-acetyltransferase 35, NatC auxiliary subunit [IPR007244]", "1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, eukaryotes [IPR027496]", "1,4-alpha-glucan-branching enzyme [IPR037439]", "1-Cys peroxiredoxin [IPR045020]", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [IPR028380]", "14-3-3 protein [IPR000308]", "14-3-3 theta [IPR042584]", "18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23-like [IPR039769]", "2-amino-3-ketobutyrate coenzyme A ligase [IPR011282]", "2-deoxynucleoside 5-phosphate N-hydrolase 1, DNPH1 [IPR028607]", "2-oxoglutarate dehydrogenase E1 component [IPR011603]", "2-phosphoglycolate phosphatase, eukaryotic [IPR006349]", "26S Proteasome non-ATPase regulatory subunit 1 [IPR035266]", "26S Proteasome non-ATPase regulatory subunit 11 [IPR035295]", "26S Proteasome non-ATPase regulatory subunit 12 [IPR035297]", "26S Proteasome non-ATPase regulatory subunit 12/COP9 signalosome complex subunit 4 [IPR040134]", "26S Proteasome non-ATPase regulatory subunit 13 [IPR035298]", "26S Proteasome non-ATPase regulatory subunit 14 [IPR035299]", "26S Proteasome non-ATPase regulatory subunit 6 [IPR035268]", "26S Proteasome non-ATPase regulatory subunit 7/8 [IPR033858]", "26S Proteasome regulatory subunit 4 [IPR035244]", "26S Proteasome regulatory subunit 6A [IPR035254]", "26S Proteasome regulatory subunit 6B [IPR035256]", "26S Proteasome regulatory subunit 7 [IPR035245]", "26S proteasome non-ATPase regulatory subunit 10-like [IPR039334]", "26S proteasome non-ATPase regulatory subunit 3 [IPR035267]", "26S proteasome non-ATPase regulatory subunit Rpn12 [IPR006746]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit [IPR016643]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit [IPR016642]", "26S proteasome regulatory subunit 10B [IPR035263]", "26S proteasome regulatory subunit P45-like [IPR005937]", "26S proteasome regulatory subunit Rpn7/COP9 signalosome complex subunit 1 [IPR019585]", "28S ribosomal protein S10, mitochondrial [IPR040055]", "28S ribosomal protein S17, mitochondrial [IPR039193]", "28S ribosomal protein S25, mitochondrial [IPR040049]", "28S ribosomal protein S27, mitochondrial [IPR019266]", "28kDa heat- and acid-stable phosphoprotein [IPR039876]", "3'-5' RNA helicase YTHDC2-like [IPR031083]", "3-hydroxyacyl-CoA dehydrogenase [IPR022694]", "3-hydroxyisobutyrate dehydrogenase [IPR011548]", "3-hydroxyisobutyrate dehydrogenase-related [IPR015815]", "3-ketodihydrosphingosine reductase KDSR-like [IPR045022]", "3-oxo-5-alpha-steroid 4-dehydrogenase/very-long-chain enoyl-CoA reductase [IPR039357]", "3-oxoacid CoA-transferase [IPR014388]", "39S ribosomal protein L40, mitochondrial [IPR039145]", "39S ribosomal protein L43/54S ribosomal protein L51 [IPR039927]", "39S ribosomal protein L46, mitochondrial [IPR040008]", "40S Ribosomal protein S10 [IPR037447]", "40S ribosomal protein S1/3, eukaryotes [IPR027500]", "40S ribosomal protein SA [IPR027504]", "4F2 cell-surface antigen heavy chain [IPR042280]", "5'-3' exoribonuclease [IPR027073]", "5'-3' exoribonuclease type 2 [IPR017151]", "5'-AMP-activated protein kinase subunit gamma-1 [IPR039166]", "5'-deoxynucleotidase YfbR/HDDC2 [IPR039356]", "5-formyltetrahydrofolate cyclo-ligase [IPR002698]", "5-lipoxygenase-activating protein [IPR001446]", "50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a [IPR028877]", "50S ribosomal protein uL4 [IPR013005]", "6-Phosphogluconolactonase [IPR039104]", "6-phosphogluconate dehydrogenase [IPR006183]", "6-phosphogluconate dehydrogenase, decarboxylating [IPR006113]", "60S acidic ribosomal protein P0 [IPR030670]", "60S ribosomal protein L18a/ L20, eukaryotes [IPR021138]", "60S ribosomal protein L19 [IPR039547]", "60S ribosomal protein L35 [IPR045059]", "60S ribosomal protein L6E [IPR000915]", "60kDa SS-A/Ro ribonucleoprotein [IPR040322]", "A-kinase anchor protein 12 [IPR028540]", "A-kinase anchor protein 13 [IPR028852]", "A-kinase anchor protein 9/Pericentrin [IPR028745]", "A-kinase anchoring protein 95 (AKAP95) [IPR007071]", "A1 cistron-splicing factor, AAR2 [IPR007946]", "AAA ATPase, CDC48 family [IPR005938]", "ABC transporter Tap-like [IPR013305]", "ABT1/Esf2 [IPR039119]", "ADF/Cofilin [IPR017904]", "ADP-ribose pyrophosphatase, mitochondrial [IPR039989]", "ADP-ribosylation factor 1-5 [IPR045872]", "ADP-ribosylation factor 6 [IPR041838]", "ADP-ribosylation factor-like protein 2 [IPR045873]", "ADP-ribosylation factor-like protein 2/3 [IPR044612]", "ADP-ribosylation factor-like protein 6 [IPR041839]", "ADP-ribosylation factor-like protein 6-interacting protein 1 [IPR033301]", "ADP-ribosylation factor-like protein 8A/8B [IPR044154]", "ADP-ribosylation/Crystallin J1 [IPR005502]", "ADP-specific phosphofructokinase/glucokinase [IPR007666]", "ADP/ATP carrier protein, eukaryotic type [IPR002113]", "AH receptor-interacting protein [IPR031208]", "AIP/AIPL1 [IPR039663]", "AP complex subunit beta [IPR026739]", "AP endonuclease 1 [IPR004808]", "AP-1/2/4 complex subunit beta [IPR016342]", "AP-2 complex subunit sigma [IPR027156]", "AP-3 complex subunit beta [IPR026740]", "ARMET-like [IPR045333]", "AT-rich interactive domain-containing protein 3 [IPR045147]", "ATP synthase membrane subunit K [IPR009125]", "ATP synthase subunit ATP5MJ, mitochondrial [IPR012574]", "ATP synthase, F0 complex, subunit A [IPR000568]", "ATP synthase, F0 complex, subunit A, bacterial/mitochondria [IPR045083]", "ATP synthase, F0 complex, subunit B [IPR013837]", "ATP synthase, F0 complex, subunit B/MI25 [IPR008688]", "ATP synthase, F0 complex, subunit D, mitochondrial [IPR008689]", "ATP synthase, F0 complex, subunit E, mitochondrial [IPR008386]", "ATP synthase, F0 complex, subunit G, mitochondrial [IPR006808]", "ATP synthase, F1 complex, alpha subunit [IPR005294]", "ATP synthase, F1 complex, beta subunit [IPR005722]", "ATP synthase, F1 complex, gamma subunit [IPR000131]", "ATP-binding cassette sub-family C member 4 [IPR030240]", "ATP-citrate synthase [IPR014608]", "ATP-dependent 6-phosphofructokinase [IPR022953]", "ATP-dependent 6-phosphofructokinase, eukaryotic-type [IPR009161]", "ATP-dependent 6-phosphofructokinase, vertebrate-type [IPR041914]", "ATP-dependent Clp protease proteolytic subunit [IPR001907]", "ATP-dependent RNA helicase DHX29 [IPR034730]", "ATP-dependent RNA helicase Ski2-like [IPR016438]", "ATP-dependent helicase Rad3/Chl1-like [IPR013020]", "ATP11 [IPR010591]", "ATP:cob(I)alamin adenosyltransferase, PduO-type [IPR029499]", "ATP:guanido phosphotransferase [IPR000749]", "ATPase family AAA domain-containing protein 2 [IPR031252]", "ATPase family AAA domain-containing protein 3 [IPR039188]", "ATPase family AAA domain-containing protein ATAD2-like [IPR045199]", "ATPase, OSCP/delta subunit [IPR000711]", "ATPase, V0 complex, subunit 116kDa, eukaryotic [IPR026028]", "ATPase, V1 complex, subunit A [IPR005725]", "ATPase, V1 complex, subunit B [IPR005723]", "ATPase, V1 complex, subunit C [IPR004907]", "ATPase, V1 complex, subunit D [IPR002699]", "ATPase, V1 complex, subunit H [IPR004908]", "ATPase, vacuolar ER assembly factor, Vma12 [IPR021013]", "Acetoacetyl-CoA synthase [IPR005914]", "Acid ceramidase-like [IPR016699]", "Acidic leucine-rich nuclear phosphoprotein 32 [IPR045081]", "Acireductone dioxygenase ARD family [IPR004313]", "Aconitase, mitochondrial-like [IPR006248]", "Aconitase/Iron-responsive element-binding protein 2 [IPR006249]", "Actin family [IPR004000]", "Actin-related protein 10 [IPR027127]", "Actin-related protein 2/3 complex subunit 1 [IPR017383]", "Actin-related protein 2/3 complex subunit 1A [IPR030140]", "Actin-related protein 2/3 complex subunit 1B [IPR030141]", "Actin-related protein 2/3 complex subunit 2 [IPR007188]", "Actin-related protein 2/3 complex subunit 3 [IPR007204]", "Actin-related protein 2/3 complex subunit 4 [IPR008384]", "Actin-related protein 3 [IPR015623]", "Actin-related protein 6 [IPR030054]", "Activating signal cointegrator 1 complex subunit 1 [IPR009210]", "Activating transcription factor 7-interacting protein [IPR026085]", "Activator of 90kDa heat shock protein ATPase-like [IPR039981]", "Activator of Hsp90 ATPase homologue 1-like [IPR013538]", "Active zone protein ELKS [IPR019323]", "Activity-dependent neuroprotector homeobox protein [IPR038861]", "Acyl-CoA desaturase [IPR015876]", "Acyl-CoA oxidase [IPR012258]", "Acyl-CoA thioesterase [IPR003703]", "Acyl-CoA-binding domain-containing protein 5 [IPR016347]", "Acyl-coenzyme A thioesterase 13 [IPR039298]", "Acylneuraminate cytidylyltransferase [IPR003329]", "Acyltransferase ChoActase/COT/CPT [IPR000542]", "Adaptor protein Cbl [IPR024162]", "Adaptor protein complex AP-1, gamma subunit [IPR017107]", "Adaptor protein complex AP-2, alpha subunit [IPR017104]", "Adaptor protein complex AP-3, delta subunit [IPR017105]", "Adaptor protein complex, sigma subunit [IPR016635]", "Adenine phosphoribosyl transferase [IPR005764]", "Adenomatous polyposis coli (APC) family [IPR026818]", "Adenomatous polyposis coli [IPR026836]", "Adenosine deaminase [IPR028893]", "Adenosine kinase [IPR001805]", "Adenosine/adenine deaminase [IPR006330]", "Adenosylhomocysteinase-like [IPR000043]", "Adenylate cyclase-associated CAP [IPR001837]", "Adenylate kinase 2 [IPR028587]", "Adenylate kinase 3/4, mitochondrial [IPR028586]", "Adenylate kinase 4, mitochondrial [IPR028585]", "Adenylate kinase isoenzyme 1 [IPR028582]", "Adenylate kinase isoenzyme 6 [IPR020618]", "Adenylate kinase subfamily [IPR006259]", "Adenylate kinase, isozyme 1/5 [IPR006267]", "Adenylate kinase/UMP-CMP kinase [IPR000850]", "Adenylosuccinate lyase [IPR004769]", "Adenylosuccinate synthetase [IPR001114]", "Adenylosuccinate synthetase isozyme 2, chordates [IPR027529]", "Adenylyl cyclase-associated protein CAP1 [IPR028415]", "Adenylyl cyclase-associated protein CAP2 [IPR028418]", "Adenylyl-sulfate kinase [IPR002891]", "AdoMet-dependent rRNA methyltransferase Spb1-like [IPR028589]", "Aladin [IPR045139]", "Alanine-tRNA ligase, class IIc [IPR002318]", "Alanine-tRNA ligase, eukaryota/bacteria [IPR023033]", "Alcohol dehydrogenase class III [IPR014183]", "Aldehyde dehydrogenase NAD(P)-dependent [IPR012394]", "Aldehyde dehydrogenase family 7 member A1-like [IPR044638]", "Aldo-keto reductase [IPR020471]", "Aldo-keto reductase family 1 member A1 [IPR044481]", "Aldose 1-/Glucose-6-phosphate 1-epimerase [IPR008183]", "Aldose 1-epimerase [IPR015443]", "Alkylated DNA repair protein AlkB [IPR004574]", "Alkyldihydroxyacetonephosphate synthase [IPR025650]", "Alpha E-catenin/Alpha T-catenin [IPR030047]", "Alpha crystallin/Small heat shock protein, animal type [IPR001436]", "Alpha-2-macroglobulin receptor-associated protein [IPR038003]", "Alpha-D-phosphohexomutase superfamily [IPR005841]", "Alpha-L-fucosidase, metazoa-type [IPR016286]", "Alpha-N-acetylglucosaminidase [IPR007781]", "Alpha-N-methyltransferase NTM1 [IPR008576]", "Alpha-adducin [IPR027766]", "Alpha-catenin [IPR001033]", "Alpha-internexin [IPR027703]", "Alpha-ketoglutarate-dependent dioxygenase FTO [IPR032868]", "Alpha/gamma-adaptin-binding protein p34 [IPR019341]", "Amidase [IPR000120]", "Amidophosphoribosyltransferase [IPR005854]", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 [IPR042360]", "Aminoacyl-tRNA synthetase, class Ic [IPR002305]", "Aminopeptidase N-type [IPR034016]", "Aminopeptidase, leukotriene A4 hydrolase-like [IPR034015]", "Aminotransferase ALAT1/2-like [IPR045088]", "Aminotransferase class IV [IPR001544]", "Aminotransferase class-III [IPR005814]", "Anamorsin [IPR007785]", "Anaphase-promoting complex subunit 1 [IPR024990]", "Anaphase-promoting complex subunit 16 [IPR029641]", "Anaphase-promoting complex subunit 2 [IPR044554]", "Anaphase-promoting complex subunit 5 [IPR037679]", "Ancient conserved domain protein family [IPR045095]", "Angiomotin [IPR009114]", "Ankycorbin [IPR042420]", "Ankyrin repeat and LEM domain-containing protein 2 [IPR035007]", "Annexin A1 [IPR002388]", "Annexin A11 [IPR008157]", "Annexin A2 [IPR002389]", "Annexin A4 [IPR002391]", "Annexin A6 [IPR002393]", "Annexin [IPR001464]", "Antifreeze, type III [IPR006013]", "Antigen peptide transporter 1 [IPR013306]", "Apoptosis inhibitory 5 [IPR008383]", "Apoptosis regulator BAX [IPR026304]", "Apoptosis regulator, Mcl-1 [IPR013281]", "Arfaptin family [IPR030798]", "Arfaptin-1 [IPR030793]", "Arginine-tRNA ligase [IPR001278]", "Arginine-tRNA-protein transferase 1, eukaryotic [IPR017137]", "Armadillo repeat protein deleted in velo-cardio-facial syndrome [IPR028444]", "Armadillo repeat-containing protein 6 [IPR040104]", "Arsenical pump ATPase, ArsA/GET3 [IPR016300]", "Arsenical pump ATPase, ArsA/GET3, eukaryotic [IPR027542]", "Arylesterase [IPR002640]", "Ashwin [IPR024887]", "Asparaginase-like 1, metazoa [IPR033844]", "Asparagine synthase, glutamine-hydrolyzing [IPR006426]", "Asparagine-tRNA ligase [IPR004522]", "Aspartate carbamoyltransferase [IPR002082]", "Aspartate-tRNA ligase, type 1 [IPR004524]", "Aspartate-tRNA synthetase, type 2 [IPR004523]", "Aspartate/ornithine carbamoyltransferase [IPR006130]", "Aspartate/other aminotransferase [IPR000796]", "Aspartyl/Asparaginyl-tRNA synthetase, class IIb [IPR002312]", "Aspartyl/asparaginyl beta-hydroxylase family [IPR039038]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit [IPR004413]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, subunit B /E [IPR017959]", "Associate of Myc 1 [IPR026060]", "Ataxin2 [IPR033093]", "Ataxin2-like [IPR045117]", "Atypical dual specificity phosphatase, subfamily A [IPR020405]", "Atypical kinase COQ8A [IPR034640]", "Autophagy protein Atg8 ubiquitin-like [IPR004241]", "Autophagy-related protein 9 [IPR007241]", "B-cell receptor-associated protein 29/31 [IPR008417]", "BAG family molecular chaperone regulator 2 [IPR037689]", "BBP/SF1 family [IPR031150]", "BCP1 family [IPR025602]", "BLOC-2 complex, Hps6 subunit [IPR017218]", "BRCA1-A complex subunit BRE [IPR010358]", "BRCA1-associated ATM activator 1 [IPR038904]", "BRCA1-associated [IPR031099]", "BRI3-binding protein [IPR033367]", "BRISC and BRCA1-A complex member 1 [IPR026126]", "BRO1 domain-containing protein BROX [IPR038898]", "Bacterial/eukaryotic lysine-tRNA ligase, class II [IPR034762]", "Baculoviral IAP repeat-containing protein 6 [IPR022103]", "Band 4.1 protein, chordates [IPR021187]", "Band 4.1-like protein 2 [IPR030546]", "Band 4.1-like protein 5 [IPR030694]", "Band-7 stomatin-like [IPR043202]", "Barrier- to-autointegration factor, BAF [IPR004122]", "Basigin [IPR044157]", "Basigin-like [IPR043204]", "Bax inhibitor 1-related [IPR006214]", "Bcl-2 family [IPR026298]", "Bcl-2-associated transcription factor 1 [IPR026668]", "Bcl-2-like protein 13 [IPR042398]", "Bcl2-like [IPR002475]", "Beta tubulin [IPR002453]", "Beta-1,4-galactosyltransferase [IPR003859]", "Beta-1,4-glucuronyltransferase 1 [IPR043189]", "Beta-N-acetylglucosaminidase [IPR011496]", "Beta-catenin [IPR013284]", "Beta-catenin-like protein 1 [IPR039678]", "Beta-galactosidase 1-like [IPR026283]", "Beta-hexosaminidase [IPR025705]", "Beta-lactamase HcpB-like [IPR040239]", "Bicaudal-D protein [IPR018477]", "Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66 [IPR013109]", "Bifunctional polynucleotide phosphatase/kinase PNKP [IPR006550]", "Bifunctional purine biosynthesis protein PurH-like [IPR002695]", "Biliverdin reductase A [IPR017094]", "Biogenesis of lysosome-related organelles complex 1 subunit 1 [IPR009395]", "Biorientation of chromosomes in cell division protein 1-like 1 [IPR043244]", "BolA protein [IPR002634]", "BolA-like protein 2 [IPR045115]", "Brain acid soluble protein 1 [IPR008408]", "Branched-chain amino acid aminotransferase II [IPR005786]", "Branched-chain aminotransferase [IPR033939]", "Breast cancer type 1 susceptibility protein (BRCA1) [IPR011364]", "Bud22/Serum response factor-binding protein 1 [IPR037393]", "Bystin [IPR007955]", "C-5 cytosine methyltransferase [IPR001525]", "C-terminal binding protein [IPR043322]", "C2 domain-containing protein 5 [IPR038983]", "CAAX prenyl protease 1 [IPR027057]", "CCR4-NOT complex, subunit 3/ 5 [IPR012270]", "CCR4-NOT transcription complex subunit 1 [IPR040398]", "CCR4-NOT transcription complex subunit 11 [IPR019312]", "CCR4-NOT transcription complex subunit 7 [IPR039636]", "CCR4-NOT transcription complex subunit 7/8/Pop2 [IPR039637]", "CCR4-NOT transcription complex subunit 9 [IPR007216]", "CD166 antigen [IPR039810]", "CD2 antigen cytoplasmic tail-binding protein 2/Lin1 [IPR039905]", "CD2-associated protein [IPR028445]", "CD36 family [IPR002159]", "CD36/scavenger receptor class B member 1 [IPR005428]", "CDC45 family [IPR003874]", "CDC50/LEM3 family [IPR005045]", "CDCA7/CDA7L [IPR040221]", "CDGSH iron-sulfur domain-containing protein 1/2 [IPR045131]", "CDK2-associated and cullin domain-containing protein 1 [IPR042652]", "CDK5 regulatory subunit-associated protein 3 [IPR008491]", "CDP-alcohol phosphatidyltransferase [IPR000462]", "CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote [IPR014387]", "CEBPZ/Mak21-like [IPR040155]", "CHORD domain containing protein [IPR039790]", "CLIP-associating protein 1 [IPR028399]", "CLU domain containing protein [IPR027523]", "COG complex component, COG2 [IPR009316]", "COMM domain-containing protein 1 [IPR037351]", "COMM domain-containing protein 10 [IPR037361]", "COMM domain-containing protein 2 [IPR037354]", "COMM domain-containing protein 7 [IPR037358]", "COMPASS component Swd2/WDR82 [IPR037867]", "COP9 Signalosome complex subunit 7A [IPR037757]", "COP9 signalosome complex subunit 1 [IPR033008]", "COP9 signalosome complex subunit 2 [IPR037750]", "COP9 signalosome complex subunit 3 [IPR037753]", "COP9 signalosome complex subunit 4 [IPR037754]", "COP9 signalosome complex subunit 5 [IPR037740]", "COP9 signalosome subunit 6 [IPR033859]", "COP9 signalosome, subunit CSN8 [IPR033205]", "COPII coat assembly protein, Sec16 [IPR024880]", "COX15/CtaA family [IPR003780]", "CPSF6/7 family [IPR034772]", "CSC1-like protein 1 [IPR026957]", "CTD phosphatase Fcp1 [IPR039189]", "CTP synthase [IPR004468]", "CWF11 family [IPR026300]", "CXXC motif containing zinc binding protein, eukaryotic [IPR008584]", "CYFIP-related Rac1 interactor [IPR039789]", "Cadherin [IPR039808]", "Calcium homeostasis endoplasmic reticulum protein [IPR039037]", "Calcium load-activated calcium channel [IPR008559]", "Calcium permeable stress-gated cation channel 1-like [IPR045122]", "Calcium uptake protein 1/2/3 [IPR039800]", "Calcium-binding mitochondrial carrier protein Aralar2 [IPR029658]", "Calcium-binding protein CAB45 [IPR027240]", "Caldesmon [IPR006017]", "Caldesmon/lymphocyte specific protein [IPR006018]", "Calpain small subunit 1 [IPR029642]", "Calpain-1 [IPR029643]", "Calpain-2 [IPR029539]", "Calpastatin [IPR026998]", "Calponin-2 [IPR029974]", "Calponin/LIMCH1 [IPR001997]", "Calreticulin [IPR009169]", "Calreticulin/calnexin [IPR001580]", "Calumenin [IPR027239]", "Caprin [IPR028816]", "Carbamoyl-phosphate synthase, large subunit [IPR006275]", "Carbamoyl-phosphate synthase, small subunit [IPR006274]", "Carbohydrate sulfotransferase 8-10 [IPR018011]", "Carboxymethylenebutenolidase homolog [IPR042946]", "Cartilage-associated protein [IPR033212]", "Casein Kinase 2, subunit alpha [IPR045216]", "Casein kinase II, regulatory subunit [IPR000704]", "Caspase-2 [IPR035702]", "Caspase-3/7 [IPR015471]", "Cat eye syndrome critical region protein 2 [IPR029614]", "Cat eye syndrome critical region protein 5 [IPR029621]", "Catechol O-methyltransferase, eukaryotic [IPR017128]", "Catenin delta-1 [IPR028439]", "Cation efflux protein [IPR002524]", "Cation-dependent mannose-6-phosphate receptor [IPR000296]", "Ccdc97-like [IPR018613]", "Cdc37 [IPR004918]", "Cdc42 [IPR037874]", "Cdc73/Parafibromin [IPR007852]", "Cell cycle and apoptosis regulator protein 2 [IPR028811]", "Cell cycle and apoptosis regulator protein [IPR025224]", "Cell cycle checkpoint, Hus1 [IPR016580]", "Cell cycle control protein 50A [IPR030351]", "Cell cycle regulator Mat89Bb [IPR019355]", "Cell division cycle protein 123 [IPR009772]", "Cell division cycle-associated 7-like protein [IPR033578]", "Cell division cycle-associated protein 2 [IPR033064]", "Cell division protein borealin [IPR018867]", "Cell growth-regulating nucleolar protein [IPR039999]", "Cell-cycle alteration and expression-elevated protein in tumour [IPR032337]", "Centrin 2 [IPR037629]", "Centromere protein I [IPR012485]", "Centromere protein U [IPR025214]", "Centrosomal protein of 170kDa [IPR026644]", "Centrosomal protein of 44kDa [IPR033603]", "Centrosomal protein of 55kDa [IPR038926]", "Ceramide glucosyltransferase [IPR025993]", "Cerebellar degeneration-related protein 2 [IPR026079]", "Ceroid-lipofuscinosis neuronal protein 5 [IPR026138]", "Ceroid-lipofuscinosis neuronal protein 6 [IPR029255]", "Cgr1-like [IPR005579]", "Chaperone DnaJ [IPR012724]", "Chaperone DnaK [IPR012725]", "Chaperone tailless complex polypeptide 1 (TCP-1) [IPR017998]", "Chaperonin Cpn60/GroEL [IPR001844]", "Chaperonin Cpn60/GroEL/TCP-1 family [IPR002423]", "Charged multivesicular body protein 1a [IPR029888]", "Checkpoint protein Hus1/Mec3 [IPR007150]", "Chitobiosyldiphosphodolichol beta-mannosyltransferase ALG1-like [IPR026051]", "Chloride channel CLIC-like [IPR009231]", "Chloride channel ClC-3 [IPR002245]", "Chloride channel, voltage gated [IPR001807]", "Chloride intracellular channel protein 1 [IPR030259]", "Chloride intracellular channel protein 4/6 [IPR030257]", "Chromatin assembly factor 1 subunit A [IPR022043]", "Chromatin assembly factor 1 subunit Cac2/CHAF1B/FAS2 [IPR045145]", "Chromatin modification-related protein Eaf6 [IPR015418]", "Chromatin-remodeling complex component Sfh1/SNF5 [IPR017393]", "Chromobox protein homologue 3 [IPR038033]", "Chromodomain-helicase-DNA-binding protein 1-like [IPR031053]", "Chromodomain-helicase-DNA-binding protein 8 [IPR034724]", "Chromosome alignment-maintaining phosphoprotein 1 [IPR039330]", "Chromosome transmission fidelity protein 8 [IPR018607]", "Cilia- and flagella-associated protein 20/CFAP20DC [IPR040441]", "Cilia- and flagella-associated protein 298 [IPR021298]", "Cip1-interacting zinc finger protein [IPR026811]", "Citrate synthase [IPR002020]", "Citrate synthase, eukaryotic-type [IPR010109]", "Claspin [IPR024146]", "Class I-like SAM-dependent O-methyltransferase [IPR002935]", "Clathrin adaptor, mu subunit [IPR001392]", "Clathrin coat assembly protein AP180-like [IPR045192]", "Clathrin interactor 1 [IPR030544]", "Clathrin light chain [IPR000996]", "Clathrin, heavy chain [IPR016341]", "Cleavage and polyadenylation specificity factor subunit 6 [IPR034769]", "Cleavage and polyadenylation specificity factor subunit 7 [IPR034770]", "Cleavage stimulation factor subunit 1-like [IPR044633]", "Cleavage stimulation factor subunit 2 [IPR033105]", "Cleavage/polyadenylation specificity factor subunit 5 [IPR016706]", "Cleft lip and palate transmembrane 1 [IPR008429]", "Cleft lip and palate transmembrane protein 1-like protein [IPR030434]", "Clp protease proteolytic subunit /Translocation-enhancing protein TepA [IPR023562]", "Clp protease, ATP-binding subunit ClpX [IPR004487]", "ClpA/B family [IPR001270]", "Clusterin [IPR016016]", "Clusterin-like [IPR000753]", "Co-chaperone protein p23-like [IPR045250]", "Coactosin-like protein [IPR030502]", "Coatomer alpha subunit [IPR016391]", "Coatomer beta subunit (COPB1) [IPR016460]", "Coatomer beta' subunit (COPB2) [IPR016453]", "Coatomer delta subunit [IPR027059]", "Coatomer gamma subunit [IPR017106]", "Coatomer subunit zeta [IPR039652]", "Coatomer, epsilon subunit [IPR006822]", "Cobalamin-dependent methionine synthase [IPR011822]", "Coenzyme A transferase family I [IPR004165]", "Cofactor of BRCA1 [IPR010405]", "Cofilin 1 [IPR027234]", "Cohesin subunit Scc3/SA [IPR039662]", "Coiled-coil domain-containing protein 124/Oxs1 [IPR010422]", "Coiled-coil domain-containing protein 138 [IPR038798]", "Coiled-coil domain-containing protein 22 [IPR008530]", "Coiled-coil domain-containing protein 43 [IPR037666]", "Coiled-coil domain-containing protein 51 [IPR037660]", "Coiled-coil domain-containing protein 86 [IPR026570]", "Coiled-coil domain-containing protein 93 [IPR039116]", "Coilin [IPR024822]", "Condensin complex subunit 2/barren [IPR022816]", "Condensin complex subunit 3 [IPR027165]", "Condensin subunit 1 [IPR007673]", "Condensin subunit 1/Condensin-2 complex subunit D3 [IPR026971]", "Condensin-2 complex subunit G2 [IPR024741]", "Condensin-2 complex subunit H2 [IPR031739]", "Conserved oligomeric Golgi complex subunit 7 [IPR019335]", "Conserved oligomeric Golgi complex, subunit 3 [IPR007265]", "Copine [IPR045052]", "Copper chaperone SCO1/SenC [IPR003782]", "Coproporphyrinogen III oxidase, aerobic [IPR001260]", "Core histone macro-H2A [IPR021171]", "Coronin 1B [IPR027340]", "Coronin 1C [IPR027333]", "Coronin [IPR015505]", "Cortactin [IPR015503]", "Cullin [IPR045093]", "Cullin-4B [IPR033044]", "Cullin-associated NEDD8-dissociated protein 1/2 [IPR039852]", "Cwf19-like protein [IPR040194]", "Cyclic nucleotide phosphodiesterase [IPR008431]", "Cyclin [IPR039361]", "Cyclin-dependent kinase 6 [IPR028788]", "Cyclophilin-RNA interacting protein [IPR035542]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase [IPR024936]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, cyclophilin A-like [IPR044666]", "Cys/Met metabolism, pyridoxal phosphate-dependent enzyme [IPR000277]", "Cysteine desulfurase IscS [IPR010240]", "Cysteine desulfurase [IPR016454]", "Cysteine protease ATG4B, metazoa [IPR032916]", "Cysteine-tRNA ligase [IPR015803]", "Cysteinyl-tRNA synthetase/mycothiol ligase [IPR024909]", "Cystinyl aminopeptidase [IPR034017]", "Cytochrome B561-related [IPR019176]", "Cytochrome P450 [IPR001128]", "Cytochrome P450, E-class, group I [IPR002401]", "Cytochrome P450, E-class, group IV [IPR002403]", "Cytochrome b-c1 complex subunit 7 [IPR003197]", "Cytochrome b-c1 complex subunit 8 [IPR004205]", "Cytochrome b-c1 complex subunit 9 [IPR008027]", "Cytochrome c oxidase assembly factor 3, mitochondrial [IPR041752]", "Cytochrome c oxidase assembly protein CtaG/Cox11 [IPR007533]", "Cytochrome c oxidase subunit 6C [IPR004204]", "Cytochrome c oxidase subunit IV [IPR013288]", "Cytochrome c oxidase subunit IV family [IPR004203]", "Cytochrome c oxidase subunit VII [IPR039297]", "Cytochrome c oxidase subunit VIIa, metazoa [IPR003177]", "Cytochrome c oxidase subunit VIIa-related, mitochondrial [IPR017267]", "Cytochrome c oxidase subunit VIIc [IPR004202]", "Cytochrome c oxidase, subunit Va/VI [IPR003204]", "Cytochrome c oxidase, subunit Vb [IPR002124]", "Cytochrome c/quinol oxidase subunit II [IPR045187]", "Cytochrome c1 [IPR002326]", "Cytoplasmic FMR1-interacting [IPR008081]", "Cytoplasmic dynein 1 intermediate chain 1/2 [IPR025956]", "Cytoplasmic dynein 2 heavy chain 1 [IPR026815]", "Cytoskeleton-associated protein 2 family [IPR026165]", "Cytoskeleton-associated protein 4 [IPR028428]", "Cytosolic acyl coenzyme A thioester hydrolase [IPR040170]", "Cytosolic nonspecific dipeptidase/DUG1 [IPR017153]", "Cytospin-A [IPR040166]", "D-3-phosphoglycerate dehydrogenase [IPR006236]", "DAD/Ost2 [IPR003038]", "DDB1- and CUL4-associated factor 8-like [IPR045151]", "DDRGK domain containing protein [IPR019153]", "DDX54/DBP10 family [IPR033517]", "DENR family, eukaryotes [IPR005873]", "DET1- and DDB1-associated protein 1 [IPR033575]", "DIS3-like exonuclease 2 [IPR028591]", "DNA (cytosine-5)-methyltransferase 1-like [IPR017198]", "DNA damage-binding protein 1 [IPR031297]", "DNA double-strand break repair protein Mre11 [IPR003701]", "DNA fragmentation factor 45 [IPR017299]", "DNA helicase, ATP-dependent, RecQ type [IPR004589]", "DNA ligase, ATP-dependent [IPR000977]", "DNA mismatch repair Msh2-type [IPR011184]", "DNA mismatch repair MutS family [IPR045076]", "DNA mismatch repair protein Msh2 [IPR032642]", "DNA mismatch repair protein MutL/Mlh/Pms [IPR038973]", "DNA mismatch repair protein MutS/MSH [IPR017261]", "DNA polymerase V/Myb-binding protein 1A [IPR007015]", "DNA polymerase alpha, subunit B [IPR016722]", "DNA polymerase delta/II small subunit family [IPR024826]", "DNA polymerase epsilon catalytic subunit [IPR029703]", "DNA polymerase epsilon, subunit B [IPR016266]", "DNA primase large subunit, eukaryotic/archaeal [IPR007238]", "DNA primase, large subunit, eukaryotic [IPR016558]", "DNA primase, small subunit [IPR002755]", "DNA primase, small subunit, eukaryotic/archaeal [IPR014052]", "DNA repair protein Rad50, eukaryotes [IPR004584]", "DNA repair/transcription protein MET18/MMS19 [IPR039920]", "DNA replication ATP-dependent helicase/nuclease Dna2 [IPR026851]", "DNA replication licensing factor Mcm2 [IPR008045]", "DNA replication licensing factor Mcm3 [IPR008046]", "DNA replication licensing factor Mcm5 [IPR008048]", "DNA replication licensing factor Mcm6 [IPR008049]", "DNA replication licensing factor Mcm7 [IPR008050]", "DNA replication/checkpoint protein [IPR021110]", "DNA topoisomerase I [IPR001631]", "DNA topoisomerase II, eukaryotic-type [IPR001154]", "DNA topoisomerase II-beta [IPR028467]", "DNA topoisomerase, type IIA [IPR001241]", "DNA-directed DNA polymerase, family B [IPR006172]", "DNA-directed RNA pol I, largest subunit [IPR015699]", "DNA-directed RNA polymerase I, subunit RPA34.5 [IPR013240]", "DNA-directed RNA polymerase II subunit Rpb4-like [IPR045222]", "DNA-directed RNA polymerase III subunit RPC3 [IPR039748]", "DNA-directed RNA polymerase subunit RPABC5/Rpb10 [IPR000268]", "DNA-directed RNA polymerase subunit Rpo5/Rpb5 [IPR014381]", "DNA-directed RNA polymerase, phage-type [IPR002092]", "DNA-directed RNA polymerase, subunit 2 [IPR015712]", "DNA-directed RNA polymerase, subunit beta-prime [IPR045867]", "DNA-directed RNA polymerases I and III subunit AC40 [IPR033901]", "DNA2/NAM7-like helicase [IPR045055]", "DPM1-like [IPR039528]", "Daxx protein [IPR005012]", "Death-inducer obliterator 1 [IPR033082]", "Dedicator of cytokinesis [IPR026791]", "Defective-in-cullin neddylation protein [IPR014764]", "Dehydrogenase/reductase SDR member 4-like [IPR029511]", "Delta l-pyrroline-5-carboxylate synthetase [IPR005766]", "Delta(24)-sterol reductase [IPR040165]", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase Ech1-like [IPR045002]", "Delta-1-pyrroline-5-carboxylate dehydrogenase [IPR005931]", "Deoxycytidylate deaminase [IPR016473]", "Deoxycytidylate deaminase-related [IPR015517]", "Deoxyhypusine hydroxylase [IPR027517]", "Deoxyhypusine synthase [IPR002773]", "Deoxyuridine triphosphate nucleotidohydrolase [IPR008181]", "Dephospho-CoA kinase [IPR001977]", "Derlin [IPR007599]", "Dermcidin [IPR028130]", "Dermcidin/Lacritin [IPR043557]", "Desmoglein [IPR009123]", "Desmoplakin [IPR028462]", "Desmosomal cadherin [IPR009122]", "Destrin [IPR029924]", "Deubiquitinating enzyme MINDY-3/4 [IPR039785]", "Developmentally regulated GTP-binding protein [IPR045001]", "Dihydrofolate reductase [IPR012259]", "Dihydrolipoamide acetyltransferase/Pyruvate dehydrogenase protein X component [IPR045257]", "Dihydrolipoamide dehydrogenase [IPR006258]", "Dihydrolipoamide succinyltransferase [IPR006255]", "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex [IPR006257]", "Dihydroorotate dehydrogenase, class 2 [IPR005719]", "Dihydropyrimidinase-related protein 2 [IPR030615]", "Dihydropyrimidinase-related protein 3 [IPR030628]", "Dihydropyrimidinase-related protein 5 [IPR030626]", "Dihydroxyacetone kinase [IPR012734]", "Dihydroxyacetone phosphate acyltransferase [IPR028353]", "Dipeptidyl-peptidase 3 [IPR005317]", "Diphthamide synthesis DHP2 [IPR010014]", "Diphthamide synthesis DPH1/DPH2 [IPR016435]", "Diphthine synthase [IPR004551]", "Dishevelled family [IPR008339]", "Dishevelled-2 [IPR008341]", "Dishevelled-related protein [IPR015506]", "Divalent ion tolerance protein, CutA [IPR004323]", "DnaJ homolog subfamily A member 1/2-like [IPR044713]", "DnaJ homolog subfamily C member 8 [IPR042858]", "DnaJ homologue subfamily C member 10 [IPR021170]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48kDa subunit [IPR005013]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit Swp1 [IPR008814]", "Dolichyldiphosphatase 1 [IPR039666]", "Drebrin [IPR028438]", "Drebrin-like protein [IPR029923]", "Dual specificity protein phosphatase 12 [IPR016278]", "Dymeclin [IPR019142]", "Dynactin subunit 3 [IPR009991]", "Dynactin subunit 4 [IPR008603]", "Dynamin [IPR022812]", "Dynamin-1-like protein [IPR030556]", "Dynamin-2 [IPR027188]", "Dynamin-like 120kDa protein, mitochondrial [IPR033047]", "Dynamitin [IPR028133]", "Dynein 1 light intermediate chain [IPR008467]", "Dynein family light intermediate chain [IPR022780]", "Dynein heavy chain [IPR026983]", "Dynein light chain, type 1/2 [IPR001372]", "Dynein regulator LIS1 [IPR017252]", "Dyslexia-associated protein KIAA0319-like [IPR029865]", "Dystrophin/utrophin [IPR035436]", "E3 SUMO-protein ligase Nse2 (Mms21) [IPR026846]", "E3 UFM1-protein ligase 1 [IPR018611]", "E3 ubiquitin ligase Bre1 [IPR013956]", "E3 ubiquitin ligase RBR family [IPR031127]", "E3 ubiquitin ligase UBR4-like [IPR045189]", "E3 ubiquitin-protein ligase ARIH2 [IPR031126]", "E3 ubiquitin-protein ligase CHIP/LubX [IPR045200]", "E3 ubiquitin-protein ligase HECTD1/TRIP12-like [IPR045322]", "E3 ubiquitin-protein ligase RBBP6 family [IPR033489]", "E3 ubiquitin-protein ligase RNF14 [IPR031128]", "E3 ubiquitin-protein ligase UBR1-like [IPR039164]", "E3 ubiquitin-protein ligase ZNF598/Hel2 [IPR044288]", "E3 ubiquitin-protein ligase listerin [IPR039795]", "E3 ubiquitin-protein ligase, SMURF1 type [IPR024928]", "EB1, Metazoa [IPR027739]", "EB2, vertebrate [IPR027735]", "ECSIT [IPR010418]", "EF-hand calcium-binding domain-containing protein 14 [IPR042352]", "EH domain-binding protein 1 [IPR029944]", "EH domain-containing protein 1/3 [IPR029951]", "EH domain-containing protein 4 [IPR029952]", "ELL/occludin family [IPR031176]", "ER lumen protein retaining receptor [IPR000133]", "ER membrane protein complex subunit 1 [IPR026895]", "ER membrane protein complex subunit 2-like [IPR039856]", "ER membrane protein complex subunit 3 [IPR008568]", "ER membrane protein complex subunit 8/9 [IPR005366]", "ERG2/sigma1 receptor-like [IPR006716]", "ERp19 [IPR037462]", "ESCRT-II complex, Vps25 subunit [IPR008570]", "Ecd family [IPR010770]", "Electron transfer flavoprotein alpha subunit/FixB [IPR001308]", "Electron transfer flavoprotein, beta subunit [IPR012255]", "Electron transfer flavoprotein-ubiquinone oxidoreductase [IPR040156]", "Elongation factor G1-like [IPR045044]", "Elongator complex protein 1 [IPR006849]", "Elongator complex protein 2 [IPR037289]", "Elongator complex protein 4 [IPR008728]", "Elongin B [IPR039049]", "Elongin-C [IPR039948]", "Emerin [IPR035004]", "Emopamil-binding protein [IPR007905]", "Endonuclease domain-containing 1 protein [IPR039015]", "Endophilin-A [IPR028501]", "Endophilin-B1 [IPR028503]", "Endoplasmic reticulum aninopeptidase 1 [IPR033520]", "Endoplasmic reticulum oxidoreductin 1 [IPR007266]", "Endoplasmic reticulum protein SC65 [IPR033213]", "Endoplasmic reticulum resident protein 29 [IPR016855]", "Endoplasmic reticulum vesicle transporter [IPR045888]", "Endosulphine [IPR006760]", "Endothelin-converting enzyme 1 [IPR029734]", "Enhancer of mRNA-decapping protein 4-like [IPR045152]", "Enhancer of rudimentary [IPR000781]", "Enolase [IPR000941]", "Enoyl-CoA hydratase/isomerase [IPR001753]", "Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type [IPR032259]", "Ependymin [IPR001299]", "Epoxide hydrolase [IPR016292]", "Epoxide hydrolase-like [IPR000639]", "Erbin [IPR032927]", "Ergosterol biosynthesis ERG4/ERG24 [IPR001171]", "Erlin1/2 [IPR033294]", "Esterase-like [IPR000801]", "Eukaryotic porin/Tom40 [IPR027246]", "Eukaryotic rRNA processing [IPR008610]", "Eukaryotic translation elongation factor 1 epsilon-1 [IPR042450]", "Eukaryotic translation initiation factor 3 subunit A [IPR027512]", "Eukaryotic translation initiation factor 3 subunit B [IPR011400]", "Eukaryotic translation initiation factor 3 subunit D [IPR007783]", "Eukaryotic translation initiation factor 3 subunit E [IPR016650]", "Eukaryotic translation initiation factor 3 subunit F [IPR027531]", "Eukaryotic translation initiation factor 3 subunit G [IPR017334]", "Eukaryotic translation initiation factor 3 subunit H [IPR027524]", "Eukaryotic translation initiation factor 3 subunit I [IPR027525]", "Eukaryotic translation initiation factor 3 subunit J [IPR013906]", "Eukaryotic translation initiation factor 3 subunit K [IPR009374]", "Eukaryotic translation initiation factor 3 subunit M [IPR027528]", "Eukaryotic translation initiation factor 3 subunit M eIF3m/COP9 signalosome complex subunit 7 COPS7 [IPR045237]", "Eukaryotic translation initiation factor 4 gamma 1 [IPR037584]", "Eukaryotic translation initiation factor 4 gamma 3 [IPR037585]", "Eukaryotic translation initiation factor 4B [IPR033107]", "Exocyst complex component EXOC2/Sec5 [IPR029175]", "Exocyst complex component EXOC3/Sec6 [IPR010326]", "Exocyst complex component EXOC5/Sec10 [IPR033960]", "Exocyst complex component EXOC6/Sec15 [IPR007225]", "Exocyst complex component Exo70 [IPR004140]", "Exocyst complex component Exo84 [IPR033961]", "Exocyst complex component Sec10-like [IPR009976]", "Exocyst complex component Sec8/EXOC4 [IPR039682]", "Exonuclease 1 [IPR032641]", "Exosome complex RNA-binding protein 1/RRP40/RRP4 [IPR026699]", "Exosome complex component Csl4 [IPR039771]", "Exosome complex component RRP45 [IPR033100]", "Exosome complex component Rrp43 [IPR033196]", "Exosome complex exonuclease Rrp6-like [IPR045092]", "Exostosin-like [IPR004263]", "Exportin 4/7-like [IPR044189]", "Exportin-1/5 [IPR045065]", "Exportin-5 [IPR040018]", "Exportin-7 [IPR040021]", "Exportin-T [IPR040017]", "Ezrin/radixin/moesin [IPR011174]", "Ezrin/radixin/moesin-like [IPR000798]", "F-actin-capping protein subunit alpha [IPR002189]", "F-actin-capping protein subunit beta [IPR001698]", "F-box-like/WD repeat-containing protein Ebi-like [IPR045183]", "FACT complex subunit Spt16 [IPR040258]", "FAD synthetase with the MoaB/Mog domain [IPR012183]", "FAD-dependent glycerol-3-phosphate dehydrogenase [IPR000447]", "FAD-dependent oxidoreductase SdhA/FrdA/AprA [IPR030664]", "FAM175 family [IPR023238]", "FAM175 family, BRISC complex, Abro1 subunit [IPR023240]", "FAM177 family [IPR028260]", "FAM98 [IPR018797]", "FH1/FH2 domain-containing protein 1 [IPR027647]", "FHF complex subunit HOOK interacting protein [IPR019384]", "FUN14 [IPR007014]", "Family of unknown function DUF5525 [IPR037656]", "Fanconi anaemia group A protein [IPR003516]", "Fanconi anaemia protein FANCD2 [IPR029448]", "Fanconi anemia group I protein [IPR026171]", "Fascin [IPR010431]", "Fascin, metazoans [IPR024703]", "Fascin-1 [IPR030146]", "Fatty acid oxidation complex, alpha subunit, mitochondrial [IPR012803]", "Fatty acid transport protein 4 [IPR030304]", "Fatty acyl-CoA reductase [IPR026055]", "Fcf2/DNTTIP2 [IPR039883]", "Ferredoxin-NADP+ reductase, adrenodoxin-type [IPR021163]", "Ferrochelatase [IPR001015]", "Fibrillarin [IPR000692]", "Filamin family [IPR044801]", "Filamin-B [IPR029874]", "Fimbrin/Plastin [IPR039959]", "Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 [IPR033756]", "Flap endonuclease 1 [IPR023426]", "Flotillin family [IPR027705]", "Formate-tetrahydrofolate ligase, FTHFS [IPR000559]", "Formin, protein diaphanous homologue 1 [IPR027653]", "Formin, protein diaphanous homologue 3 [IPR027654]", "Four and a half LIM domains protein 1 [IPR042997]", "Fragile X mental retardation syndrome-related protein [IPR040148]", "Fructose-bisphosphate aldolase, class-I [IPR000741]", "Fumarate hydratase, class II [IPR005677]", "Fumarate lyase family [IPR000362]", "Fumarylacetoacetase [IPR005959]", "Fyv10 family [IPR045098]", "G-protein alpha subunit, group 12/13 [IPR000469]", "G-protein alpha subunit, group I [IPR001408]", "G-protein alpha subunit, group Q [IPR000654]", "G-protein, gamma subunit [IPR001770]", "G-rich sequence factor 1 [IPR033106]", "G10 protein [IPR001748]", "G2 and S phase-expressed protein 1 [IPR026659]", "GDP dissociation inhibitor [IPR018203]", "GDP-fucose protein O-fucosyltransferase 1 [IPR039922]", "GDP-fucose protein O-fucosyltransferase [IPR019378]", "GDP-mannose 4,6-dehydratase [IPR006368]", "GH3 family [IPR004993]", "GINS complex subunit Sld5 [IPR008591]", "GINS complex, subunit Psf3 [IPR010492]", "GOLM1/CASC4 family [IPR026139]", "GPI ethanolamine phosphate transferase 2 [IPR039527]", "GPI transamidase component PIG-T [IPR007245]", "GPI-anchor transamidase [IPR028361]", "GPN-loop GTPase 1 [IPR030230]", "GPN-loop GTPase [IPR004130]", "GRASP55/65 [IPR007583]", "GRIM-19 [IPR009346]", "GTP-binding protein 1 [IPR039263]", "GTP-binding protein Era [IPR005662]", "GTP-binding protein Obg/CgtA [IPR014100]", "GTP-binding protein Rheb [IPR037586]", "Galactokinase [IPR000705]", "Gamma-adducin [IPR027772]", "Gamma-glutamylcyclotransferase [IPR017939]", "Gamma-glutamyltranspeptidase [IPR000101]", "Gamma-tubulin complex component protein [IPR007259]", "Ganglioside GM2 activator [IPR028996]", "Ganglioside-induced differentiation-associated protein 1 [IPR034336]", "Gasdermin-E [IPR042377]", "Gdt1 family [IPR001727]", "Gem-associated protein 4 [IPR033265]", "Gemini of Cajal bodies-associated protein 8 [IPR034754]", "General transcription factor 3C polypeptide 4 [IPR044230]", "Geranylgeranyl transferase type-1 subunit beta [IPR041960]", "Geranylgeranyl transferase type-2 subunit alpha [IPR032955]", "Geranylgeranyl transferase type-2 subunit beta [IPR026873]", "Girdin [IPR027717]", "Glia maturation factor [IPR011171]", "Glomulin/ALF4 [IPR019516]", "Glu-tRNAGln amidotransferase C subunit [IPR003837]", "Glucosamine 6-phosphate N-acetyltransferase [IPR039143]", "Glucosamine-6-phosphate isomerase [IPR004547]", "Glucosamine-fructose-6-phosphate aminotransferase, isomerising [IPR005855]", "Glucose-6-phosphate dehydrogenase [IPR001282]", "Glucosidase II beta subunit-like [IPR039794]", "Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase [IPR005715]", "Glutamate carboxypeptidase 2-like [IPR039373]", "Glutamate--cysteine ligase regulatory subunit [IPR032963]", "Glutamate-tRNA ligase, bacterial/mitochondrial [IPR004527]", "Glutamate/acetylglutamate kinase [IPR001057]", "Glutamate/phenylalanine/leucine/valine dehydrogenase [IPR006095]", "Glutaminase [IPR015868]", "Glutamine-tRNA synthetase [IPR004514]", "Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic [IPR004526]", "Glutamyl-tRNA(Gln) amidotransferase A subunit [IPR004412]", "Glutamyl/glutaminyl-tRNA synthetase [IPR000924]", "Glutathione S-transferase Omega/Tau-like [IPR045073]", "Glutathione S-transferase kappa [IPR044088]", "Glutathione S-transferase, Mu class [IPR003081]", "Glutathione S-transferase, alpha class [IPR003080]", "Glutathione S-transferase, omega-class [IPR005442]", "Glutathione S-transferases, class Zeta [IPR005955]", "Glutathione Transferase family [IPR040079]", "Glutathione reductase, eukaryote/bacterial [IPR006322]", "Glutathione synthase [IPR005615]", "Glutathione-specific gamma-glutamylcyclotransferase [IPR006840]", "Glyceraldehyde-3-phosphate dehydrogenase, type I [IPR006424]", "Glyceraldehyde/Erythrose phosphate dehydrogenase family [IPR020831]", "Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase [IPR022284]", "Glycerol-3-phosphate acyltransferase, PlsB [IPR028354]", "Glycine cleavage system P protein [IPR020581]", "Glycine dehydrogenase (decarboxylating) [IPR003437]", "Glycogen debranching enzyme [IPR010401]", "Glycogen debranching enzyme, metazoa [IPR006421]", "Glycogen synthase [IPR008631]", "Glycogen synthase kinase-3 beta [IPR033573]", "Glycogen/starch/alpha-glucan phosphorylase [IPR011833]", "Glycoside hydrolase family 30 [IPR001139]", "Glycoside hydrolase family 31 [IPR000322]", "Glycoside hydrolase family 47 [IPR001382]", "Glycoside hydrolase family 63 [IPR004888]", "Glycoside hydrolase, family 2 [IPR006101]", "Glycoside hydrolase, family 27 [IPR002241]", "Glycoside hydrolase, family 29 [IPR000933]", "Glycoside hydrolase, family 35 [IPR001944]", "Glycosyl transferase, family 13 [IPR004139]", "Glycosyl transferase, family 25 [IPR002654]", "Glycosyl transferase, family 31 [IPR002659]", "Glycosyl transferase, family 35 [IPR000811]", "Glycosyl transferase, family 8 [IPR002495]", "Glycyl-tRNA synthetase [IPR002315]", "Glycyl-tRNA synthetase/DNA polymerase subunit gamma-2 [IPR027031]", "Glyoxalase I [IPR004361]", "Glyoxalase domain-containing protein 4 [IPR043193]", "Golgi apparatus protein 1 [IPR039728]", "Golgi integral membrane protein 4 [IPR042336]", "Golgi membrane protein 1 [IPR026143]", "Golgi phosphoprotein 3-like [IPR008628]", "Golgi to ER traffic protein 4 [IPR007317]", "Golgi-associated PDZ and coiled-coil motif-containing protein [IPR038879]", "Golgin subfamily A [IPR024858]", "Golgin subfamily A member 3 [IPR033288]", "Golgin subfamily A member 5 [IPR019177]", "Golgin subfamily B member 1 [IPR026202]", "Graves disease carrier protein [IPR002167]", "GroES chaperonin family [IPR020818]", "Growth arrest/ DNA-damage-inducible protein-interacting protein 1 [IPR018472]", "GrpE nucleotide exchange factor [IPR000740]", "Guanine nucleotide binding protein (G-protein), alpha subunit [IPR001019]", "Guanine nucleotide exchange factor Ect2 [IPR026817]", "Guanine nucleotide exchange factor, Ric8 [IPR019318]", "Guanine nucleotide-exchange factor Sec12-like [IPR045260]", "H/ACA ribonucleoprotein complex, subunit Gar1/Naf1 [IPR007504]", "H/ACA ribonucleoprotein complex, subunit Nhp2, eukaryote [IPR002415]", "HAD hydrolase, LHPP/HDHD2 [IPR006355]", "HAD hydrolase, subfamily IA [IPR006439]", "HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase [IPR008380]", "HAD-superfamily hydrolase, subfamily IIA [IPR006357]", "HAD-superfamily hydrolase, subfamily IIA, CECR5 [IPR006353]", "HAUS augmin-like complex subunit 1 [IPR026243]", "HAUS augmin-like complex subunit 2 [IPR028346]", "HAUS augmin-like complex subunit 2, metazoa [IPR026242]", "HAUS augmin-like complex subunit 3 [IPR026206]", "HAUS augmin-like complex subunit 4 [IPR029327]", "HAUS augmin-like complex subunit 4, metazoa [IPR026214]", "HAUS augmin-like complex subunit 5 [IPR029131]", "HAUS augmin-like complex subunit 6 [IPR026797]", "HAUS complex subunit 5, metazoa [IPR026215]", "HCCA isomerase/glutathione S-transferase kappa [IPR014440]", "HEXIM [IPR024872]", "HIRA-interacting protein 3 [IPR037647]", "HMG domain-containing protein 4 [IPR042477]", "HMG-CoA lyase [IPR043594]", "HS1-associating protein X-1 [IPR017248]", "Haem oxygenase [IPR002051]", "Haem oxygenase-like [IPR016053]", "Haloacid dehalogenase-like hydrolase [IPR041492]", "Ham1-like protein [IPR002637]", "Heat shock 70kDa protein 13 [IPR042048]", "Heat shock protein 70 family [IPR013126]", "Heat shock protein Hsp90 family [IPR001404]", "Heat shock protein Sti1-like [IPR045248]", "Helicase MOV-10 [IPR026122]", "Helicase XPB/Ssl2 [IPR001161]", "Helicase superfamily 1/2, DinG/Rad3-like [IPR045028]", "Heme A synthase, type 2 [IPR023754]", "Heparan sulphate 2-O-sulfotransferase [IPR007734]", "Heterochromatin protein 1-binding protein 3 [IPR033061]", "Heterogeneous nuclear ribonucleoprotein C [IPR017347]", "Heterogeneous nuclear ribonucleoprotein K [IPR033090]", "Heterogeneous nuclear ribonucleoprotein M [IPR024667]", "Heterogeneous nuclear ribonucleoprotein U [IPR026745]", "Heterogeneous nuclear ribonucleoprotein U-like protein 1 [IPR027025]", "Hexokinase [IPR001312]", "High mobility group protein HMG-I/HMG-Y, chordates [IPR031079]", "High mobility group protein HMGA [IPR000116]", "High mobility group protein HMGB1 [IPR031076]", "High mobility group protein HMGB3 [IPR031077]", "High mobility group protein HMGN [IPR000079]", "Higher eukaryotic phosphomevalonate kinase [IPR005919]", "Histidine acid phosphatase, eukaryotic [IPR016274]", "Histidine phosphatase superfamily, clade-1 [IPR013078]", "Histidine phosphatase superfamily, clade-2 [IPR000560]", "Histidine triad (HIT) protein [IPR001310]", "Histidine-tRNA ligase [IPR015807]", "Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit [IPR004516]", "Histone H2A [IPR002119]", "Histone H4 [IPR001951]", "Histone acetyltransferase type B, catalytic subunit [IPR017380]", "Histone acetyltransferases subunit 3 [IPR019340]", "Histone deacetylase [IPR003084]", "Histone deacetylase complex subunit SAP130 [IPR024137]", "Histone deacetylase complex, SAP18 subunit [IPR017250]", "Histone deacetylase family [IPR000286]", "Histone demethylase JHDM2-like [IPR045109]", "Histone lysine-specific demethylase [IPR017366]", "Histone methyltransferase complex subunit ASH2 [IPR037353]", "Histone-lysine N-methyltransferase 2A [IPR037927]", "Histone-lysine N-methyltransferase EHMT1/EHMT2 [IPR043550]", "Histone-lysine N-methyltransferase EHMT2 [IPR038034]", "Histone-lysine N-methyltransferase, SET [IPR017155]", "HnRNP R/Q splicing factor [IPR006535]", "HnRNP-L/PTB [IPR006536]", "Holocytochrome c/c1 synthase [IPR000511]", "Host cell factor 1 [IPR037854]", "Host cell factor [IPR043536]", "Huntingtin [IPR000091]", "Huntingtin family [IPR028426]", "Huntingtin-interacting protein 1 [IPR030554]", "Hydantoinase/dihydropyrimidinase [IPR011778]", "Hydroxyacylglutathione hydrolase [IPR017782]", "Hydroxymethylglutaryl-CoA synthase, eukaryotic [IPR010122]", "Hypoxanthine phosphoribosyl transferase [IPR005904]", "I-BAR domain containing protein IRSp53 [IPR030128]", "I-BAR domain containing protein IRSp53/IRTKS/Pinkbar [IPR027681]", "I-BAR domain containing protein MTSS1/MTSS2 [IPR030127]", "I-BAR domain containing protein MTSS2 [IPR030059]", "ICln [IPR003521]", "ISC system FeS cluster assembly, IscU scaffold [IPR011339]", "Immunity-related GTPase family Q protein [IPR040070]", "Importin beta family [IPR040122]", "Importin subunit alpha [IPR024931]", "Inhibitor of nuclear factor kappa-B kinase-interacting protein [IPR024152]", "Initiation factor 2B-related [IPR000649]", "Initiation factor 4G [IPR045208]", "Inner centromere protein [IPR039130]", "Inner nuclear membrane protein Man1 [IPR034997]", "Inorganic pyrophosphatase [IPR008162]", "Inosine triphosphate pyrophosphatase [IPR027502]", "Inosine-5'-monophosphate dehydrogenase [IPR005990]", "Inositol 3,4-bisphosphate 4-phosphatase [IPR039034]", "Inositol monophosphatase [IPR033942]", "Inositol monophosphatase, lithium-sensitive [IPR020552]", "Inositol monophosphatase-like [IPR000760]", "Insulin receptor substrate [IPR039011]", "Insulin-like growth factor 2 mRNA-binding protein 2 [IPR028743]", "Integral membrane protein EMC3/TMCO1-like [IPR002809]", "Integrator complex subunit 1 [IPR038902]", "Integrator complex subunit 12 [IPR039053]", "Integrator complex subunit 14 [IPR039841]", "Integrator complex subunit 3 [IPR045334]", "Integrator complex subunit 7 [IPR033060]", "Integrator complex subunit 9 [IPR027074]", "Integrin beta subunit [IPR015812]", "Integrin beta-1 subunit [IPR027071]", "Interferon gamma receptor alpha subunit [IPR008355]", "Interferon-induced protein with tetratricopeptide repeat 5 [IPR024125]", "Interferon-stimulated 20kDa exonuclease-like 2 [IPR034933]", "Interleukin enhancer-binding factor 3 [IPR033099]", "Intersectin-2 [IPR027029]", "Intracellular chloride channel [IPR002946]", "Intracellular hyaluronic acid binding protein [IPR026203]", "Intracellular lipid binding protein [IPR031259]", "Intraflagellar transport protein 27 homologue, eukaryotes [IPR034112]", "Intron Large complex component GCFC2-like [IPR012890]", "Inverted formin-2 [IPR027649]", "Iron regulatory protein 1 [IPR029784]", "Iron-sulfur protein NUBPL-like [IPR044304]", "Isochorismatase domain-containing protein 2 [IPR040318]", "Isocitrate dehydrogenase NAD-dependent [IPR004434]", "Isocitrate dehydrogenase NADP-dependent [IPR004790]", "Isoleucine-tRNA ligase [IPR002301]", "Isoleucine-tRNA ligase, type 1 [IPR023585]", "Isoleucine-tRNA ligase, type 2 [IPR023586]", "Isopentenyl-diphosphate delta-isomerase, type 1 [IPR011876]", "Isoprenylcysteine carboxyl methyltransferase [IPR007269]", "Isovaleryl-CoA dehydrogenase [IPR034183]", "J-protein Zuotin/DnaJC2 [IPR044634]", "JNK-interacting protein 3/4 [IPR039911]", "JmjC domain-containing [IPR039994]", "Junction plakoglobin [IPR030461]", "Junctional adhesion molecule A [IPR042456]", "KH domain-containing BBP-like [IPR045071]", "KIF-1 binding protein [IPR022083]", "KIN17-like protein [IPR037321]", "KRR1 interacting protein 1 [IPR018034]", "Kae1/TsaD family [IPR017861]", "Keratin, type I [IPR002957]", "Keratinocyte-associated transmembrane protein 2 [IPR037645]", "Kindlin/fermitin [IPR037843]", "Kinectin [IPR024854]", "Kinesin light chain [IPR002151]", "Kinesin-like protein KIF15/KIN-12E [IPR044986]", "Kinesin-like protein KIF20A [IPR027326]", "Kinesin-like protein KIF20B [IPR028828]", "Kinesin-like protein KIF22 (Kid) [IPR026986]", "Kinesin-like protein [IPR027640]", "Kinetochore protein Ndc80 [IPR005550]", "Kinetochore protein Spc25 [IPR045143]", "Kinetochore-Ndc80 subunit Spc24 [IPR013252]", "Ku70 [IPR006165]", "Ku80 [IPR024193]", "L-lactate dehydrogenase [IPR011304]", "L-lactate/malate dehydrogenase [IPR001557]", "LAMTOR1/MEH1 [IPR028209]", "LAR-interacting protein, Liprin [IPR029515]", "LEM domain-containing protein 2 [IPR034994]", "LETM1/MDM38-like [IPR044202]", "LIM domain and actin-binding protein 1 [IPR028740]", "LIM domain and actin-binding protein LIMA-like [IPR045268]", "La domain containing protein [IPR045180]", "Las1 [IPR007174]", "Lecithin:cholesterol/phospholipid:diacylglycerol acyltransferase [IPR003386]", "Lethal(2) giant larvae protein [IPR000664]", "Leucine carboxyl methyltransferase 1 [IPR016651]", "Leucine zipper putative tumor suppressor [IPR045329]", "Leucine zipper putative tumour suppressor 2 [IPR028597]", "Leucine zipper transcription factor-like protein 1 [IPR026157]", "Leucine-rich PPR motif-containing protein [IPR033490]", "Leucine-rich repeat protein SHOC2 [IPR027036]", "Leucine-rich repeat-containing 41 [IPR026137]", "Leucine-tRNA ligase [IPR002302]", "Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic [IPR004493]", "Leukocyte elastase inhibitor (serpin B1) [IPR015557]", "Leukocyte surface antigen CD47 [IPR006704]", "Leukotriene A4 hydrolase/leucine aminopeptidase [IPR012777]", "Leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase [IPR014190]", "LicD family [IPR007074]", "Like-Sm (LSM) domain containing protein, LSm4/SmD1/SmD3 [IPR027141]", "Linker histone H1/H5 [IPR005819]", "Lipase maturation factor [IPR009613]", "Lipase, eukaryotic [IPR025483]", "Liprin-alpha-1 [IPR030438]", "LisH domain-containing protein ARMC9 [IPR040369]", "Lon protease [IPR027065]", "Lon protease homologue, chloroplastic/mitochondrial [IPR027503]", "Lon protease, bacterial/eukaryotic-type [IPR004815]", "Long-chain fatty acid CoA synthetase, eukaryotic [IPR045311]", "Low temperature viability protein Ltv1 [IPR007307]", "Luc7-related [IPR004882]", "Lupus La protein [IPR002344]", "Lysine-tRNA ligase, class II [IPR002313]", "Lysophosphatidylserine lipase ABHD12 [IPR026605]", "Lysosomal thioesterase PPT2 [IPR030295]", "Lysosome membrane protein II [IPR005429]", "Lysosome-associated membrane glycoprotein [IPR002000]", "M-phase inducer phosphatase [IPR000751]", "M-phase phosphoprotein 6 [IPR019324]", "MCT-1/Tma20 [IPR016437]", "MCU family [IPR039055]", "MDN2-binding protein [IPR039061]", "METTL16/RlmF family [IPR010286]", "MICAL-like protein [IPR028563]", "MICOS complex subunit MIC19/MIC25 [IPR007964]", "MICOS complex subunit MIC26/MIC27 [IPR019166]", "MICOS complex subunit MIC26/MIC27, animal [IPR033182]", "MICOS complex subunit Mic13 [IPR026769]", "MKRN-like [IPR045072]", "MOB kinase activator family [IPR005301]", "MRG [IPR008676]", "MRPS27/PTCD2 [IPR034913]", "MT-A70-like [IPR007757]", "Macrophage migration inhibitory factor [IPR001398]", "Magnesium transporter protein 1 [IPR006844]", "Major centromere autoantigen B [IPR033062]", "Major facilitator superfamily [IPR011701]", "Mak16 protein [IPR006958]", "Malate dehydrogenase, NAD-dependent, cytosolic [IPR011274]", "Malate dehydrogenase, type 1 [IPR010097]", "Malate dehydrogenase, type 2 [IPR010945]", "Malectin [IPR039155]", "Malic oxidoreductase [IPR001891]", "Manganese/iron superoxide dismutase [IPR001189]", "Mannose-6-phosphate isomerase [IPR016305]", "Mannose-6-phosphate isomerase, type I [IPR001250]", "Mannose-6-phosphate receptor [IPR028927]", "Matrix-remodeling-associated protein 7 [IPR026622]", "Mediator complex, subunit Med14 [IPR013947]", "Mediator complex, subunit Med16 [IPR021665]", "Mediator complex, subunit Med21 [IPR021384]", "Mediator complex, subunit Med23 [IPR021629]", "Mediator complex, subunit Med24, [IPR021429]", "Mediator complex, subunit Med4 [IPR019258]", "Medium-chain dehydrogenase/reductase [IPR045010]", "Medium-chain specific acyl-CoA dehydrogenase [IPR034180]", "Melanoma-associated antigen D1 [IPR030083]", "Melanoma-associated antigen D2 [IPR028810]", "Melanoma-associated antigen [IPR037445]", "Membrane insertase YidC/ALB3/OXA1/COX18 [IPR001708]", "Membrane bound O-acyl transferase, MBOAT [IPR004299]", "Membrane magnesium transporter [IPR018937]", "Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein [IPR001129]", "Mesoderm induction early response protein/metastasis-associated protein [IPR040138]", "Metal-dependent protein hydrolase [IPR003226]", "Metastasis-associated protein MTA2 [IPR037964]", "Methionine-tRNA ligase, type 1 [IPR023458]", "Methionyl-tRNA synthetase [IPR014758]", "Methyl-CpG binding protein MeCP2 [IPR017353]", "Methyl-CpG binding protein MeCP2/MBD4 [IPR045138]", "Methylcrotonoyl-CoA carboxylase beta chain MCCB/AccD1-like [IPR045190]", "Methylmalonate-semialdehyde dehydrogenase [IPR010061]", "Methylpurine-DNA glycosylase [IPR003180]", "Methylthioadenosine phosphorylase (MTAP) [IPR010044]", "Methylthiotransferase [IPR005839]", "Methyltransferase METTL16/PsiM [IPR017182]", "Methyltransferase Ppm1/Ppm2/Tcmp [IPR007213]", "Methyltransferase, trithorax [IPR016569]", "Mevalonate kinase [IPR006205]", "Mevalonate/galactokinase [IPR006206]", "Mff/Tango-11 [IPR008518]", "MiaB-like tRNA modifying enzyme, archaeal-type [IPR006466]", "Microfibrillar-associated protein 1 [IPR033194]", "Microprocessor complex subunit DGCR8 [IPR040375]", "Microtubule associated protein 1 [IPR026074]", "Microtubule associated protein 1A [IPR015656]", "Microtubule-associated protein 1B [IPR027321]", "Microtubule-associated protein 1S [IPR027322]", "Microtubule-associated protein 4 [IPR027323]", "Microtubule-associated protein 7 family [IPR008604]", "Microtubule-associated protein Jupiter [IPR033335]", "Microtubule-associated protein RP/EB [IPR027328]", "Microtubule-associated protein, MAP65/Ase1/PRC1 [IPR007145]", "Midasin [IPR012099]", "Midline-1 [IPR027727]", "Mini-chromosome maintenance complex protein 4 [IPR008047]", "Mini-chromosome maintenance complex-binding protein [IPR019140]", "Mini-chromosome maintenance protein [IPR031327]", "Minichromosome maintenance protein 10 [IPR040184]", "Mitochondria fission 1 protein [IPR016543]", "Mitochondrial 18kDa protein [IPR019560]", "Mitochondrial 28S ribosomal protein S31 [IPR026299]", "Mitochondrial 28S ribosomal protein S34 [IPR032053]", "Mitochondrial ATP synthase subunit g, animal [IPR016702]", "Mitochondrial ATPase inhibitor [IPR007648]", "Mitochondrial F1-F0 ATP synthase subunit F, predicted [IPR019344]", "Mitochondrial Rho GTPase 1 [IPR029506]", "Mitochondrial Rho GTPase [IPR021181]", "Mitochondrial antiviral-signalling protein, metazoan [IPR026148]", "Mitochondrial carrier UCP-like [IPR002030]", "Mitochondrial carrier protein Mtm1-like [IPR045315]", "Mitochondrial carrier protein [IPR002067]", "Mitochondrial glycoprotein [IPR003428]", "Mitochondrial import inner membrane translocase subunit Tim44 [IPR017303]", "Mitochondrial import inner membrane translocase subunit Tim50 [IPR027111]", "Mitochondrial import inner membrane translocase subunit Tim8/13 [IPR039238]", "Mitochondrial import receptor subunit TOM5, metazoa [IPR029179]", "Mitochondrial import receptor subunit Tom22 [IPR005683]", "Mitochondrial inner membrane protein Mitofilin [IPR019133]", "Mitochondrial inner membrane translocase complex, subunit Tim17 [IPR005678]", "Mitochondrial inner membrane translocase complex, subunit Tim23 [IPR005681]", "Mitochondrial intermembrane space import and assembly protein 40 [IPR039289]", "Mitochondrial outer membrane translocase complex, subunit Tom5 [IPR019603]", "Mitochondrial outer membrane transport complex protein, metaxin [IPR017410]", "Mitochondrial phosphate carrier protein Pic2/Mir1-like [IPR044677]", "Mitochondrial processing peptidase subunit beta [IPR037718]", "Mitochondrial pyruvate carrier [IPR005336]", "Mitochondrial ribonuclease P catalytic subunit [IPR033495]", "Mitochondrial-processing peptidase subunit alpha [IPR037715]", "Mitofusin family [IPR027094]", "Mitofusin-1 [IPR027088]", "Mitofusin-2 [IPR027089]", "Mitogen-activated protein (MAP) kinase p38-like [IPR008352]", "Mitogen-activated protein (MAP) kinase phosphatase [IPR008343]", "Mitogen-activated protein (MAP) kinase, ERK1/2 [IPR008349]", "Mitogen-activated protein kinase 14 [IPR038784]", "Mitotic spindle checkpoint protein Bub1/Mad3 [IPR015661]", "Mo25-like [IPR013878]", "Molecular chaperone regulator BAG [IPR039773]", "Molybdate-anion transporter [IPR008509]", "Molybdate-anion transporter, animal type [IPR030163]", "Molybdopterin biosynthesis protein MoeA-like [IPR038987]", "Monocarboxylate transporter 1 [IPR030757]", "Monocarboxylate transporter [IPR004743]", "Monothiol glutaredoxin-related [IPR004480]", "Mortality factor 4-like protein 1 [IPR038011]", "Mpv17/PMP22 [IPR007248]", "Mrp/NBP35 ATP-binding protein [IPR019591]", "Multidrug resistance protein 1 [IPR030258]", "Multifunctional methyltransferase subunit Trm112 [IPR039127]", "Multiple myeloma tumor-associated protein 2-like [IPR039207]", "Myelin expression factor 2 [IPR034632]", "Myeloid-derived growth factor [IPR018887]", "Myo-inositol-1-phosphate synthase [IPR002587]", "Myotubularin family [IPR030564]", "Myristoyl-CoA:protein N-myristoyltransferase [IPR000903]", "Myristoylated alanine-rich C-kinase substrate MARCKS [IPR002101]", "N-acetyl-D-glucosamine kinase NAGK-like [IPR039758]", "N-acetylglucosamine-6-sulfatase [IPR012251]", "N-acetylglucosamine-6-sulfatase, metazoan [IPR015981]", "N-acetylglucosaminyl phosphatidylinositol deacetylase-related [IPR003737]", "N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase [IPR039516]", "N-acetyltransferase Ard1-like [IPR045047]", "N-alpha-acetyltransferase 40 [IPR039949]", "N-cadherin [IPR030051]", "N-end rule aminoacyl transferase [IPR030700]", "N-terminal acetyltransferase A, auxiliary subunit [IPR021183]", "N6-adenosine-methyltransferase MT-A70-like [IPR025848]", "NAD kinase 2, mitochondrial [IPR012355]", "NAD kinase [IPR002504]", "NAD(P) transhydrogenase, alpha subunit [IPR026255]", "NAD(P)H-quinone oxidoreductase subunit D/H [IPR022885]", "NAD/FAD transporter SLC25A32-like [IPR044712]", "NADH dehydrogenase 1, beta subcomplex, subunit 6 [IPR019174]", "NADH dehydrogenase, subunit C [IPR010218]", "NADH ubiquinone oxidoreductase, F subunit [IPR011537]", "NADH-plastoquinone oxidoreductase, chain 5 subgroup [IPR018393]", "NADH-quinone oxidoreductase subunit E-like [IPR002023]", "NADH-quinone oxidoreductase, chain 5-like [IPR003945]", "NADH-quinone oxidoreductase, chain I [IPR010226]", "NADH-ubiquinone oxidoreductase, 20 Kd subunit [IPR006138]", "NADH-ubiquinone oxidoreductase, subunit 10 [IPR019377]", "NADH-ubiquinone reductase complex 1 MLRQ subunit [IPR010530]", "NADH:cytochrome b5 reductase-like [IPR001834]", "NADH:ubiquinone oxidoreductase, ESSS subunit [IPR019329]", "NADH:ubiquinone oxidoreductase, subunit G [IPR010228]", "NADH:ubiquinone oxidoreductase, subunit NDUFB4 [IPR009866]", "NADPH-cytochrome P450 reductase [IPR023208]", "NDRG [IPR004142]", "NDUFAF3/Mth938 domain-containing protein [IPR007523]", "NEDD8 ultimate buster 1 [IPR039749]", "NEDD8-activating enzyme E1 catalytic subunit [IPR030468]", "NEDD8-activating enzyme E1 regulatory subunit APP-BP1 [IPR030667]", "NF-kappa-B/Dorsal [IPR000451]", "NOL6/Upt22 [IPR005554]", "NPC1-like [IPR004765]", "NSF attachment protein [IPR000744]", "Na(+)/H(+) exchange regulatory cofactor NHERF-1 [IPR031199]", "Na(+)/H(+) exchange regulatory cofactor NHERF-1/2 [IPR017300]", "Nck-associated protein 1 [IPR019137]", "Negative elongation factor E [IPR033102]", "Nesprin-2 [IPR030266]", "Nestin [IPR031211]", "Neural Wiskott-Aldrich syndrome protein [IPR030214]", "Neurochondrin [IPR008709]", "Neurofilament light polypeptide [IPR027692]", "Neurofilament medium polypeptide [IPR027697]", "Neuroplastin [IPR027112]", "Neutral amino acid SLC6 transporter [IPR002438]", "Nibrin [IPR016592]", "Nibrin-related [IPR040227]", "Nicalin [IPR016574]", "Nicastrin [IPR008710]", "Nicotinamide phosphoribosyl transferase [IPR016471]", "Nitric oxide synthase-interacting protein [IPR016818]", "Nonaspanin (TM9SF) [IPR004240]", "Nonsense-mediated mRNA decay protein 3 [IPR039722]", "Nonsense-mediated mRNA decay protein Nmd2/UPF2 [IPR039762]", "Not2/Not3/Not5 [IPR040168]", "Nuclear RNA export factor [IPR030217]", "Nuclear cap-binding protein subunit 1 [IPR027159]", "Nuclear factor NF-kappa-B, p105 subunit [IPR030503]", "Nuclear factor hnRNPA1 [IPR021662]", "Nuclear fragile X mental retardation-interacting protein 2 [IPR032747]", "Nuclear mitotic apparatus protein 1 [IPR026650]", "Nuclear polyadenylated RNA-binding protein Nab2/ZC3H14 [IPR040366]", "Nuclear pore complex protein NUP98-NUP96 [IPR037637]", "Nuclear pore complex protein Nup133-like [IPR037624]", "Nuclear pore complex protein [IPR026054]", "Nuclear pore glycoprotein p62, metazoa [IPR033072]", "Nuclear pore membrane glycoprotein 210-like [IPR045197]", "Nuclear pore protein 84/107 [IPR007252]", "Nuclear protein DGCR14/ESS-2 [IPR019148]", "Nuclear protein localization protein 4 [IPR016563]", "Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 [IPR026633]", "Nucleobindin [IPR040250]", "Nucleobindin-1 [IPR040253]", "Nucleobindin-2 [IPR028813]", "Nucleolar GTP-binding protein 1 [IPR024926]", "Nucleolar GTP-binding protein 2 [IPR024929]", "Nucleolar complex protein 2 [IPR005343]", "Nucleolar complex protein 4 [IPR027193]", "Nucleolar complex-associated protein 3 [IPR016903]", "Nucleolar pre-ribosomal-associated protein 1 [IPR039844]", "Nucleolar protein 10/Enp2 [IPR040382]", "Nucleolar protein 11 [IPR042859]", "Nucleolar protein 14 [IPR007276]", "Nucleolar protein 7 [IPR039626]", "Nucleolar protein 9 [IPR040000]", "Nucleolar protein Nop56/Nop58 [IPR045056]", "Nucleolar, Nop52 [IPR010301]", "Nucleoplasmin family [IPR004301]", "Nucleoporin NSP1/NUP62 [IPR026010]", "Nucleoporin NUP88/NUP82 [IPR037700]", "Nucleoporin Nup120/160 [IPR021717]", "Nucleoporin Nup186/Nup192/Nup205 [IPR021827]", "Nucleoporin Nup188 [IPR044840]", "Nucleoporin Nup37 [IPR037626]", "Nucleoporin Nup54/Nup57/Nup44 [IPR024864]", "Nucleoporin Nup85-like [IPR011502]", "Nucleoporin Nup88 [IPR019321]", "Nucleoporin Seh1 [IPR037597]", "Nucleoporin interacting component Nup93/Nic96 [IPR007231]", "Nucleoporin p58/p45 [IPR024882]", "Nucleoporin peptidase S59-like [IPR037665]", "Nucleoporin protein Ndc1-Nup [IPR019049]", "Nucleoporin, NUP53 [IPR017389]", "Nucleoporin, Nup155-like [IPR004870]", "Nucleoside 2-deoxyribosyltransferase [IPR007710]", "Nucleoside diphosphate kinase [IPR001564]", "Nucleoside-triphosphatase, THEP1 type [IPR004948]", "Nucleosome assembly protein (NAP) [IPR002164]", "Nucleosome-remodeling factor subunit BPTF [IPR038028]", "NudC domain-containing protein 1 [IPR037895]", "NudC domain-containing protein 3 [IPR027761]", "NudC family [IPR037898]", "OBG-type GTPase [IPR045086]", "OCIA domain-containing protein 1/2 [IPR040187]", "ORC ubiquitin ligase 1 [IPR039209]", "Oligoribonuclease [IPR022894]", "Oligosaccharyl transferase complex, subunit OST3/OST6 [IPR021149]", "Oligosaccharyl transferase, STT3 subunit [IPR003674]", "Optic atrophy 3-like [IPR010754]", "Origin recognition complex, subunit 3 [IPR020795]", "Origin recognition complex, subunit 5 [IPR020796]", "Ornithine aminotransferase [IPR010164]", "Orotate phosphoribosyltransferase [IPR023031]", "Orotidine 5'-phosphate decarboxylase [IPR014732]", "Oxidized purine nucleoside triphosphate [IPR003563]", "Oxysterol-binding protein [IPR000648]", "P-type ATPase [IPR001757]", "P-type ATPase subfamily IIC, subunit alpha [IPR005775]", "P-type ATPase, subfamily IIA, SERCA-type [IPR005782]", "P-type ATPase, subfamily V [IPR006544]", "P-type ATPase, subfamily IIB [IPR006408]", "PA2G4 family [IPR004545]", "PAT complex subunit CCDC47 [IPR012879]", "PAX-interacting protein 1 [IPR037886]", "PDCD5-like [IPR002836]", "PDK/BCKDK protein kinase [IPR039028]", "PDZ and LIM domain protein 1 [IPR028537]", "PDZ domain-containing protein 8 [IPR039275]", "PEST proteolytic signal-containing nuclear protein [IPR029169]", "PEX5/PEX5L [IPR024111]", "PH-interacting protein [IPR028738]", "PHD finger protein 10 [IPR038045]", "PHF5-like [IPR005345]", "PITH domain-containing protein 1-like [IPR045099]", "PNN-interacting serine/arginine-rich protein [IPR031937]", "PP2B [IPR043360]", "Pachytene checkpoint protein 2-like [IPR044539]", "Palmitoyl protein thioesterase [IPR002472]", "Palmitoyl-protein thioesterase 1 [IPR030294]", "Pantothenate kinase, acetyl-CoA regulated, two-domain type [IPR015844]", "Paraneoplastic encephalomyelitis antigen [IPR002343]", "Paraoxonase2 [IPR008364]", "Partner of Y14 and mago [IPR039333]", "Pat1-like [IPR039900]", "Pentatricopeptide repeat domain-containing protein 3 [IPR037387]", "Peptidase A22B, signal peptide peptidase [IPR007369]", "Peptidase C13, legumain [IPR001096]", "Peptidase C14 family [IPR002398]", "Peptidase C1B, bleomycin hydrolase [IPR004134]", "Peptidase C2, calpain family [IPR022684]", "Peptidase C26 [IPR011697]", "Peptidase C26, gamma-glutamyl hydrolase [IPR015527]", "Peptidase C54 [IPR005078]", "Peptidase C65, otubain [IPR019400]", "Peptidase C69, dipeptidase A [IPR005322]", "Peptidase C78, ubiquitin fold modifier-specific peptidase 1/ 2 [IPR012462]", "Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930]", "Peptidase M1, aminopeptidase B [IPR015571]", "Peptidase M13 [IPR000718]", "Peptidase M14B, caboxypeptidase D [IPR015567]", "Peptidase M17, leucine aminopeptidase [IPR023042]", "Peptidase M17, leucine aminopeptidase/peptidase B [IPR011356]", "Peptidase M20 [IPR002933]", "Peptidase M24, methionine aminopeptidase [IPR001714]", "Peptidase M24A, methionine aminopeptidase, subfamily 1 [IPR002467]", "Peptidase M24A, methionine aminopeptidase, subfamily 2 [IPR002468]", "Peptidase M28 family [IPR045175]", "Peptidase M3A/M3B [IPR045090]", "Peptidase S10, serine carboxypeptidase [IPR001563]", "Peptidase S26B [IPR001733]", "Peptidase S28 [IPR008758]", "Peptidase S8, subtilisin-related [IPR015500]", "Peptidase S9A, prolyl oligopeptidase [IPR002470]", "Peptidase T1A, proteasome beta-subunit [IPR000243]", "Peptidase T2, asparaginase 2 [IPR000246]", "Peptidase family M49 [IPR039461]", "Peptidase, FtsH [IPR005936]", "Peptide chain release factor eRF1/aRF1 [IPR004403]", "Peptidyl-prolyl cis-trans isomerase E [IPR016304]", "Peptidyl-prolyl cis-trans isomerase FKBP2/11 [IPR044609]", "Peptidyl-prolyl cis-trans isomerase FKBP3 [IPR043368]", "Peptidyl-prolyl cis-trans isomerase FKBP4 [IPR031212]", "Peptidyl-prolyl cis-trans isomerase FKBP5 [IPR031210]", "Peptidyl-prolyl cis-trans isomerase PIN4 [IPR043323]", "Peptidyl-tRNA hydrolase, PTH2 [IPR002833]", "Pericentriolar material 1 protein [IPR024138]", "Perilipin [IPR004279]", "Periodic tryptophan protein 1 [IPR044285]", "Periodic tryptophan protein 2 [IPR027145]", "Periphilin-1 [IPR028851]", "Peroxiredoxin, AhpC-type [IPR024706]", "Peroxiredoxin-5-like [IPR037944]", "Peroxiredoxin-like 2A [IPR032802]", "Peroxiredoxin-like 2A/B/C [IPR032801]", "Peroxisomal acyl-coenzyme A oxidase [IPR034171]", "Peroxisomal membrane protein 14 [IPR025655]", "Peroxisomal targeting signal 1 receptor PEX5, animals [IPR024113]", "Peroxysomal long chain fatty acyl transporter [IPR005283]", "Pescadillo [IPR010613]", "Pex19 protein [IPR006708]", "Phenylalanine-tRNA ligase, class IIc, beta subunit [IPR045060]", "Phenylalanyl-tRNA synthetase, class IIc, alpha subunit [IPR004529]", "Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archael/eukaryotic type [IPR004531]", "Phosducin-like [IPR045037]", "Phosphatidate cytidylyltransferase [IPR000374]", "Phosphatidate cytidylyltransferase, eukaryota [IPR016720]", "Phosphatidate cytidylyltransferase, mitochondrial [IPR015222]", "Phosphatidyl serine synthase [IPR004277]", "Phosphatidylethanolamine-binding protein [IPR008914]", "Phosphatidylethanolamine-binding protein, eukaryotic [IPR035810]", "Phosphatidylinositol 3-kinase, Vps34 type [IPR008290]", "Phosphatidylinositol kinase [IPR015433]", "Phosphatidylinositol transfer protein [IPR001666]", "Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase beta [IPR016280]", "Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma [IPR016279]", "Phosphatidylinositol-4-phosphate 5-kinase [IPR023610]", "Phosphatidylinositol-binding clathrin assembly protein [IPR030412]", "Phosphatidylinositol-glycan biosynthesis class S protein [IPR019540]", "Phosphatidylserine decarboxylase [IPR033177]", "Phosphatidylserine decarboxylase, eukaryotic type 1 [IPR033661]", "Phosphatidylserine decarboxylase-related [IPR003817]", "Phosphoacetylglucosamine mutase [IPR016657]", "Phosphodiesterase MJ0936/Vps29 [IPR000979]", "Phosphoenolpyruvate carboxykinase, GTP-utilising [IPR008209]", "Phosphoglucomutase [IPR045244]", "Phosphoglucose isomerase (PGI) [IPR001672]", "Phosphoglycerate kinase [IPR001576]", "Phosphoglycerate mutase 1 [IPR005952]", "Phosphoinositide phospholipase C family [IPR001192]", "Phospholipase B-like [IPR007000]", "Phosphoribosylformylglycinamidine cyclo-ligase [IPR004733]", "Phosphoribosylformylglycinamidine synthase PurL [IPR010073]", "Phosphoribosylglycinamide formyltransferase [IPR004607]", "Phosphoribosylglycinamide synthetase [IPR000115]", "Phosphorylated adapter RNA export protein [IPR039047]", "Phosphoserine aminotransferase [IPR022278]", "Phosphoserine phosphatase [IPR004469]", "Phosphotyrosyl phosphatase activator, PTPA [IPR004327]", "Pinin [IPR039853]", "Pirin [IPR012093]", "Plakin [IPR043197]", "Plakophilin/Delta catenin [IPR028435]", "Plasma membrane calcium-transporting ATPase 1 [IPR030320]", "Plasminogen activator inhibitor 1 RNA-binding protein [IPR027205]", "Plastin-1 [IPR030235]", "Plastin-2/3 [IPR039956]", "Plectin [IPR030269]", "Polo kinase kinase [IPR022165]", "Poly(A) polymerase [IPR014492]", "Poly(ADP-ribose) glycohydrolase [IPR007724]", "Poly-U binding splicing factor, PUF60-like [IPR006532]", "Polyadenylate binding protein, human types 1, 2, 3, 4 [IPR006515]", "Polyadenylate-binding protein 2 [IPR034911]", "Polyadenylate-binding protein-interacting protein 2-like [IPR040396]", "Polynucleotide kinase 3 phosphatase [IPR013954]", "Polyprenyl synthetase [IPR000092]", "Polyribonucleotide 5-hydroxyl-kinase Clp1/Grc3 [IPR045116]", "Polyribonucleotide nucleotidyltransferase [IPR012162]", "Porin, eukaryotic type [IPR001925]", "Porphobilinogen deaminase [IPR000860]", "Pre-mRNA-processing factor 19 [IPR038959]", "Pre-mRNA-processing factor 6/Prp1/STA1 [IPR027108]", "Pre-mRNA-processing factor Prp40 [IPR039726]", "Pre-mRNA-processing-splicing factor 8 [IPR027652]", "Pre-mRNA-splicing factor Cwf15/Cwc15 [IPR006973]", "Pre-mRNA-splicing factor 38 [IPR005037]", "Pre-mRNA-splicing factor Cwc2/Slt11 [IPR039171]", "Pre-mRNA-splicing factor Isy1 [IPR009360]", "Pre-mRNA-splicing factor SLU7 [IPR039974]", "Pre-mRNA-splicing factor SPF27 [IPR008409]", "Pre-mRNA-splicing factor Spp2-like [IPR045166]", "Pre-mRNA-splicing factor Syf1-like [IPR045075]", "Pre-mRNA-splicing regulator WTAP [IPR033757]", "Pre-rRNA-processing protein Esf1 [IPR039754]", "Pre-rRNA-processing protein PNO1-like [IPR039912]", "Pre-rRNA-processing protein TSR2 [IPR019398]", "Prefoldin alpha subunit, archaea-type [IPR011599]", "Prefoldin alpha-like [IPR004127]", "Prefoldin beta-like [IPR002777]", "Prefoldin subunit 2 [IPR027235]", "Prefoldin subunit 3 [IPR016655]", "Prefoldin, subunit 4 [IPR016661]", "Prenylated rab acceptor PRA1 [IPR004895]", "Prenylcysteine oxidase [IPR017046]", "Prenyltransferase subunit beta [IPR045089]", "Presenilin/signal peptide peptidase [IPR006639]", "Primosome PriB/single-strand DNA-binding [IPR000424]", "Probable E3 ubiquitin-protein ligase makorin-2 [IPR026293]", "Probable ubiquitin carboxyl-terminal hydrolase FAF-X [IPR031226]", "Profilin [IPR005455]", "Profilin-1 [IPR029892]", "Profilin-2 [IPR029891]", "Profilin1/2/3, vertebrate [IPR005454]", "Progesterone-induced-blocking factor 1 [IPR026205]", "Prohibitin [IPR000163]", "Proliferating cell nuclear antigen, PCNA [IPR000730]", "Proline-rich AKT1 substrate 1 protein [IPR026682]", "Proline-rich protein PRCC [IPR018800]", "Proline-tRNA ligase, class IIa, archaeal-type [IPR004499]", "Proline/serine-rich coiled-coil protein 1/G2 and S phase-expressed protein 1 [IPR026657]", "Prolyl 3-hydroxylase 1 [IPR039837]", "Prolyl 3-hydroxylase [IPR039575]", "Prolyl 4-hydroxylase [IPR045054]", "Prostaglandin E synthase 2 [IPR034334]", "Prostaglandin reductase 2 [IPR037399]", "Proteasomal ubiquitin receptor Rpn13/ADRM1 [IPR006773]", "Proteasome B-type subunit [IPR023333]", "Proteasome activator PA28 [IPR009077]", "Proteasome activator complex subunit 4 [IPR035309]", "Proteasome alpha-type subunit [IPR023332]", "Proteasome assembly chaperone 1 [IPR016565]", "Proteasome assembly chaperone 2 [IPR019151]", "Proteasome assembly chaperone 2, eukaryotic [IPR016562]", "Proteasome assembly chaperone 3 [IPR018788]", "Proteasome beta 3 subunit [IPR033811]", "Proteasome component Ecm29 [IPR024372]", "Proteasome inhibitor PI31-like [IPR045128]", "Proteasome subunit alpha 1 [IPR035144]", "Proteasome subunit alpha 3 [IPR037555]", "Proteasome subunit alpha 7 [IPR035190]", "Proteasome subunit alpha2 [IPR034644]", "Proteasome subunit alpha4 [IPR034647]", "Proteasome subunit alpha5 [IPR033812]", "Proteasome subunit alpha6 [IPR034642]", "Proteasome subunit beta 1 [IPR035202]", "Proteasome subunit beta 2 [IPR035206]", "Proteasome subunit beta 4 [IPR016295]", "Proteasome subunit beta 5 [IPR037558]", "Proteasome subunit beta 6 [IPR035140]", "Proteasome subunit beta 7 [IPR035216]", "Proteasome, subunit alpha/beta [IPR001353]", "Protein AATF/Bfr2 [IPR039223]", "Protein BRAWNIN [IPR027858]", "Protein CDV3 [IPR026806]", "Protein CIP2A [IPR042510]", "Protein CUSTOS [IPR026694]", "Protein Cms1 [IPR032704]", "Protein DEK [IPR044198]", "Protein ERGIC-53 [IPR033085]", "Protein FAM118 [IPR038916]", "Protein FAM118B [IPR033352]", "Protein Hgh1 [IPR039717]", "Protein ICln/Lot5/Saf5 [IPR039924]", "Protein LYRIC [IPR031402]", "Protein LZIC [IPR040065]", "Protein Lsm12-like [IPR039683]", "Protein NDRG3 [IPR030692]", "Protein PBDC1, metazoa/fungi [IPR008476]", "Protein PRRC1 [IPR026534]", "Protein PRRC2 [IPR033184]", "Protein Peter Pan-like [IPR045112]", "Protein RCC2 [IPR028641]", "Protein Red-like [IPR039896]", "Protein S100-A10 [IPR028476]", "Protein S100-A11 [IPR028482]", "Protein S100-A13 [IPR028487]", "Protein SMG8 [IPR028802]", "Protein SON [IPR032922]", "Protein Sgt1-like [IPR044563]", "Protein Spindly, chordates [IPR028593]", "Protein TFG [IPR033512]", "Protein XRP2 [IPR039093]", "Protein Yip1/4-like [IPR045231]", "Protein arginine N-methyltransferase PRMT5 [IPR007857]", "Protein arginine N-methyltransferase [IPR025799]", "Protein arginine methyltransferase NDUFAF7 [IPR003788]", "Protein canopy homolog [IPR042415]", "Protein disulfide-isomerase A6-like [IPR044569]", "Protein disulphide isomerase [IPR005792]", "Protein disulphide-isomerase A4 [IPR017068]", "Protein farnesyltransferase subunit beta [IPR026872]", "Protein flightless-1 [IPR029919]", "Protein furry/Tao3/Mor2 [IPR039867]", "Protein import receptor MAS20 [IPR002056]", "Protein import receptor MAS20, metazoan [IPR022422]", "Protein jagunal [IPR009787]", "Protein kinase C and casein kinase substrate in neurons protein 2 [IPR028521]", "Protein kinase C and casein kinase substrate in neurons protein 3 [IPR028523]", "Protein kinase C, delta [IPR027436]", "Protein kinase C, delta/epsilon/eta/theta types [IPR014376]", "Protein kinase C-binding protein 1 [IPR021931]", "Protein kinase Mps1 family [IPR027084]", "Protein of unknown function DUF1075 [IPR009432]", "Protein of unknown function DUF2046 [IPR019152]", "Protein of unknown function DUF2452 [IPR019534]", "Protein of unknown function DUF4726 [IPR031714]", "Protein of unknown function DUF719 [IPR007998]", "Protein patched/dispatched [IPR003392]", "Protein phosphatase 1 regulatory subunit 12A/B/C [IPR017401]", "Protein phosphatase 2A regulatory subunit PR55 [IPR000009]", "Protein phosphatase 2A, regulatory B subunit, B56 [IPR002554]", "Protein phosphatase 2C family [IPR015655]", "Protein phosphatase 4 core regulatory subunit R2 [IPR015267]", "Protein phosphatase methylesterase, eukaryotic [IPR016812]", "Protein regulator of cytokinesis 1 [IPR032921]", "Protein spinster-like [IPR044770]", "Protein strawberry notch [IPR026741]", "Protein transport Sec61-beta/Sbh [IPR030671]", "Protein transport protein Got1 [IPR045176]", "Protein transport protein SEC31-like [IPR040251]", "Protein transport protein Sec23 [IPR037364]", "Protein transport protein SecG/Sec61-beta/Sbh [IPR016482]", "Protein virilizer [IPR026736]", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase [IPR000682]", "Protein-S-isoprenylcysteine O-methyltransferase [IPR025770]", "Protein-glutamate O-methyltransferase [IPR039763]", "Protein-tyrosine phosphatase, low molecular weight [IPR017867]", "Protein-tyrosine phosphatase, low molecular weight, mammalian [IPR002115]", "Protein-tyrosine phosphatase, non-receptor type-1/2 [IPR012265]", "Protein-tyrosine phosphatase, non-receptor type-6, -11 [IPR012152]", "Protein-tyrosine phosphatase-like, PTPLA [IPR007482]", "Protein/nucleic acid deglycase DJ-1 [IPR006287]", "Proteinase inhibitor I25A, stefin [IPR001713]", "Protoporphyrinogen oxidase [IPR004572]", "Pseudouridine synthase I, TruA [IPR001406]", "Pseudouridine synthase PUS1/ PUS2-like [IPR041708]", "Pseudouridine synthase, RluC/RluD [IPR006225]", "Pseudouridine synthase, TruD [IPR001656]", "Pterin 4 alpha carbinolamine dehydratase [IPR001533]", "Pumilio homologue 3 [IPR040059]", "Purine 5'-nucleotidase [IPR016695]", "Purine nucleoside phosphorylase I, inosine/guanosine-specific [IPR011270]", "Purine nucleoside phosphorylase [IPR011268]", "Purine-rich element binding protein family [IPR006628]", "Purine-rich element-binding protein alpha [IPR030500]", "Putative RNA methyltransferase [IPR003750]", "Putative RNA-binding protein 47 [IPR034442]", "Putative peptidyl-tRNA hydrolase PTRHD1 [IPR042237]", "Pyridine nucleotide-disulphide oxidoreductase, class I [IPR001100]", "Pyridoxal phosphate homeostasis protein [IPR011078]", "Pyridoxal phosphate-dependent decarboxylase [IPR002129]", "Pyridoxamine 5'-phosphate oxidase [IPR000659]", "Pyridoxine kinase [IPR004625]", "Pyrimidine 5'-nucleotidase, eukaryotic [IPR006434]", "Pyrroline-5-carboxylate reductase [IPR000304]", "Pyruvate carboxylase [IPR005930]", "Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y [IPR017597]", "Pyruvate dehydrogenase E1 component subunit beta [IPR027110]", "Pyruvate kinase [IPR001697]", "Queuine tRNA-ribosyltransferase accessory subunit QTRTD1 [IPR028592]", "RAB11-binding protein RELCH [IPR040362]", "RAD3/XPD family [IPR001945]", "RINT-1/Tip20 [IPR007528]", "RLI1 [IPR013283]", "RNA (C5-cytosine) methyltransferase [IPR023267]", "RNA (C5-cytosine) methyltransferase, NOP2 [IPR023273]", "RNA 3'-terminal phosphate cyclase [IPR000228]", "RNA 3'-terminal phosphate cyclase type 1 [IPR017770]", "RNA 3'-terminal phosphate cyclase type 2 [IPR016443]", "RNA binding protein HABP4/SERBP1 [IPR039764]", "RNA cap guanine-N2 methyltransferase [IPR019012]", "RNA cytidine acetyltransferase NAT10 [IPR033688]", "RNA demethylase ALKBH5 [IPR032860]", "RNA exonuclease 4 [IPR034920]", "RNA methyltransferase Bin3-like [IPR039772]", "RNA polymerase I associated factor, A49-like [IPR009668]", "RNA polymerase II associated factor Paf1 [IPR007133]", "RNA polymerase II elongation factor ELL [IPR031184]", "RNA polymerase II transcription factor SIII, subunit A [IPR010684]", "RNA polymerase II transcriptional coactivator Sub1/Tcp4-like [IPR045125]", "RNA polymerase II-associated protein RPAP1/Rba50 [IPR039913]", "RNA polymerase subunit Rpb4/RPC9 [IPR005574]", "RNA polymerase subunit Rpb7-like [IPR045113]", "RNA polymerase-associated protein Ctr9 [IPR031101]", "RNA transcription, translation and transport factor protein [IPR019265]", "RNA-binding motif protein 8 [IPR008111]", "RNA-binding protein 10 [IPR033095]", "RNA-binding protein 26 [IPR034861]", "RNA-binding protein 26/27 [IPR045137]", "RNA-binding protein 5 [IPR033094]", "RNA-binding protein EWS [IPR033109]", "RNA-binding protein FUS [IPR034459]", "RNA-binding protein NOB1 [IPR039907]", "RNA-binding protein Nova-1 [IPR033086]", "RNA-induced silencing complex, nuclease component Tudor-SN [IPR016685]", "RNA-splicing ligase RtcB homologue, eukaryotic [IPR027513]", "RNA-splicing ligase, RtcB [IPR001233]", "RNase P subunit p30 [IPR002738]", "ROK family [IPR000600]", "RPA-related protein RADX [IPR040893]", "RZZ complex, subunit Zw10 [IPR009361]", "RZZ complex, subunit Zwilch [IPR018630]", "Rab GDI protein [IPR000806]", "Rab GTPase-activating protein 1 [IPR033185]", "Rab-like protein 6 [IPR040385]", "Rab21 [IPR041833]", "Rab24 [IPR041828]", "Rab35 [IPR041815]", "Rab3GAP catalytic subunit [IPR045700]", "Rab3GAP regulatory subunit [IPR026059]", "Rab4 [IPR041819]", "Rab9 [IPR041824]", "Rabaptin [IPR003914]", "Rabaptin-5 [IPR029880]", "Rad21/Rec8-like protein [IPR039781]", "Ragulator complex protein LAMTOR2-like [IPR037587]", "RalBP1-associated Eps domain-containing protein 1 [IPR026814]", "Ran GTPase [IPR002041]", "Ran binding protein RanBP1-like [IPR045255]", "Ran-interacting Mog1 protein [IPR007681]", "Rap guanine nucleotide exchange factor 2 [IPR030739]", "Rap1 GTPase-GDP dissociation stimulator 1 [IPR040144]", "Ras GTPase GNL1-like [IPR043358]", "Ras GTPase-activating protein-binding protein 1 [IPR034375]", "Ras GTPase-activating protein-binding protein 2 [IPR034377]", "Ras GTPase-activating protein-binding protein [IPR039539]", "Ras-like guanine nucleotide exchange factor [IPR008937]", "Ras-related protein Rab14 [IPR030702]", "Ras-related protein Ral [IPR028412]", "Reduced folate carrier [IPR002666]", "Reduced folate transporter SLC19A1 [IPR028339]", "Regulatory associated protein of TOR [IPR004083]", "Remodeling and spacing factor 1-like [IPR028938]", "Remodelling complex subunit Rsc/polybromo [IPR037382]", "Renin receptor-like [IPR012493]", "Replication factor A protein 1 [IPR004591]", "Replication factor A protein 2 [IPR014646]", "Replication factor A protein 3 [IPR013970]", "Replication factor A protein-like [IPR040260]", "Replication factor C subunit 1 [IPR012178]", "Replication termination factor 2 [IPR006735]", "Reticulophagy receptor 1/3 [IPR043384]", "Reticulophagy regulator 3 [IPR033361]", "Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit [IPR017287]", "Retinoblastoma-binding protein 5/Swd1 [IPR037850]", "Retrieval of early ER protein Rer1 [IPR004932]", "Rho GDP/GTP exchange factor Kalirin/TRIO [IPR028570]", "Rho protein GDP-dissociation inhibitor [IPR000406]", "Rho-associated protein kinase 1/2 [IPR020684]", "Rho-related GTP-binding protein RhoG [IPR042734]", "Ribonuclease CAF1 [IPR006941]", "Ribonuclease H2 subunit B [IPR040456]", "Ribonuclease H2, subunit A [IPR004649]", "Ribonuclease HII/HIII [IPR001352]", "Ribonuclease III [IPR011907]", "Ribonuclease Nob1, eukaryote [IPR017117]", "Ribonuclease T2, eukaryotic [IPR033697]", "Ribonuclease T2-like [IPR001568]", "Ribonucleases P/MRP protein subunit Pop1 [IPR039182]", "Ribonucleoprotein PTB-binding 1 [IPR034635]", "Ribonucleoside-diphosphate reductase large subunit [IPR039718]", "Ribonucleotide reductase small subunit [IPR033909]", "Ribonucleotide reductase small subunit family [IPR000358]", "Ribophorin I [IPR007676]", "Ribose-phosphate pyrophosphokinase [IPR005946]", "Ribose-phosphate pyrophosphokinase, bacterial-type [IPR037515]", "Ribosomal RNA adenine dimethylase [IPR011530]", "Ribosomal RNA adenine methyltransferase KsgA/Erm [IPR001737]", "Ribosomal RNA assembly KRR1 [IPR024166]", "Ribosomal RNA large subunit methyltransferase E [IPR015507]", "Ribosomal RNA processing protein 8 [IPR007823]", "Ribosomal RNA-processing protein 15 [IPR012459]", "Ribosomal RNA-processing protein Rrp9-like [IPR039241]", "Ribosomal biogenesis NSA2 family [IPR039411]", "Ribosomal biogenesis regulatory protein [IPR007023]", "Ribosomal biogenesis, methyltransferase, EMG1/NEP1 [IPR005304]", "Ribosomal export protein Nmd3 [IPR039768]", "Ribosomal protein L1 [IPR002143]", "Ribosomal protein L1, mitochondrial [IPR005879]", "Ribosomal protein L1/ribosomal biogenesis protein [IPR028364]", "Ribosomal protein L10P [IPR001790]", "Ribosomal protein L10e [IPR001197]", "Ribosomal protein L11, bacterial-type [IPR006519]", "Ribosomal protein L11/L12 [IPR000911]", "Ribosomal protein L12/P1/P2 family [IPR027534]", "Ribosomal protein L13 [IPR005822]", "Ribosomal protein L13, eukaryotic/archaeal [IPR005755]", "Ribosomal protein L13e [IPR001380]", "Ribosomal protein L14 [IPR039660]", "Ribosomal protein L14P [IPR000218]", "Ribosomal protein L15 [IPR030878]", "Ribosomal protein L15, bacterial-type [IPR005749]", "Ribosomal protein L15e [IPR000439]", "Ribosomal protein L16 [IPR000114]", "Ribosomal protein L17 [IPR000456]", "Ribosomal protein L18e [IPR000039]", "Ribosomal protein L19 [IPR001857]", "Ribosomal protein L2 [IPR002171]", "Ribosomal protein L2, archaeal-type [IPR023672]", "Ribosomal protein L21 [IPR001787]", "Ribosomal protein L21-like [IPR028909]", "Ribosomal protein L21e [IPR001147]", "Ribosomal protein L22, bacterial/chloroplast-type [IPR005727]", "Ribosomal protein L22/L17 [IPR001063]", "Ribosomal protein L22/L17, eukaryotic/archaeal [IPR005721]", "Ribosomal protein L22e [IPR002671]", "Ribosomal protein L23 [IPR019985]", "Ribosomal protein L24e [IPR023438]", "Ribosomal protein L24e-related [IPR000988]", "Ribosomal protein L25/L23 [IPR013025]", "Ribosomal protein L26/L24, eukaryotic/archaeal [IPR005756]", "Ribosomal protein L27e [IPR001141]", "Ribosomal protein L28/L24 [IPR026569]", "Ribosomal protein L28/L40, mitochondrial [IPR019192]", "Ribosomal protein L28e [IPR002672]", "Ribosomal protein L29/L35 [IPR001854]", "Ribosomal protein L29e [IPR002673]", "Ribosomal protein L3 [IPR000597]", "Ribosomal protein L3, archaeal/eukaryotic type [IPR045077]", "Ribosomal protein L3, bacterial/organelle-type [IPR019927]", "Ribosomal protein L30/YlxQ [IPR039109]", "Ribosomal protein L30e [IPR000231]", "Ribosomal protein L31e [IPR000054]", "Ribosomal protein L32e [IPR001515]", "Ribosomal protein L34Ae [IPR008195]", "Ribosomal protein L35A [IPR001780]", "Ribosomal protein L36e [IPR000509]", "Ribosomal protein L37/S30 [IPR010793]", "Ribosomal protein L37ae [IPR002674]", "Ribosomal protein L37e [IPR001569]", "Ribosomal protein L38e [IPR002675]", "Ribosomal protein L4, eukaryotic and archaeal type [IPR045240]", "Ribosomal protein L4/L1e [IPR002136]", "Ribosomal protein L44e [IPR000552]", "Ribosomal protein L47, mitochondrial [IPR010729]", "Ribosomal protein L5 [IPR002132]", "Ribosomal protein L5 eukaryotic/L18 archaeal [IPR005485]", "Ribosomal protein L50, mitochondria [IPR018305]", "Ribosomal protein L55, mitochondrial [IPR018615]", "Ribosomal protein L6 [IPR000702]", "Ribosomal protein L7, eukaryotic [IPR005998]", "Ribosomal protein L7/L12 [IPR000206]", "Ribosomal protein L7/L30 [IPR039699]", "Ribosomal protein L7A/L8 [IPR001921]", "Ribosomal protein L7Ae/L8/Nhp2 family [IPR018492]", "Ribosomal protein L9 [IPR000244]", "Ribosomal protein P2 [IPR044076]", "Ribosomal protein S10 [IPR001848]", "Ribosomal protein S10, eukaryotic/archaeal [IPR005729]", "Ribosomal protein S11 [IPR001971]", "Ribosomal protein S12/S23 [IPR006032]", "Ribosomal protein S12e [IPR000530]", "Ribosomal protein S13 [IPR001892]", "Ribosomal protein S15 [IPR000589]", "Ribosomal protein S15, bacterial-type [IPR005290]", "Ribosomal protein S15P [IPR023029]", "Ribosomal protein S16 [IPR000307]", "Ribosomal protein S17, archaeal/eukaryotic [IPR028333]", "Ribosomal protein S17/S11 [IPR000266]", "Ribosomal protein S17e [IPR001210]", "Ribosomal protein S18 [IPR001648]", "Ribosomal protein S19/S15 [IPR002222]", "Ribosomal protein S19A/S15e [IPR005713]", "Ribosomal protein S19e [IPR001266]", "Ribosomal protein S2 [IPR001865]", "Ribosomal protein S2, bacteria/mitochondria/plastid [IPR005706]", "Ribosomal protein S2, eukaryotic [IPR027498]", "Ribosomal protein S2, eukaryotic/archaeal [IPR005707]", "Ribosomal protein S21e [IPR001931]", "Ribosomal protein S22, mitochondrial [IPR019374]", "Ribosomal protein S23, eukaryotic/archaeal [IPR005680]", "Ribosomal protein S23, mitochondrial [IPR019520]", "Ribosomal protein S23/S29, mitochondrial [IPR019368]", "Ribosomal protein S24/S35, mitochondrial [IPR039848]", "Ribosomal protein S24e [IPR001976]", "Ribosomal protein S25 [IPR004977]", "Ribosomal protein S26e [IPR000892]", "Ribosomal protein S28, mitochondrial [IPR019375]", "Ribosomal protein S28e [IPR000289]", "Ribosomal protein S29, mitochondrial [IPR008092]", "Ribosomal protein S3, eukaryotic/archaeal [IPR005703]", "Ribosomal protein S30 [IPR006846]", "Ribosomal protein S30, mitochondrial [IPR039982]", "Ribosomal protein S3Ae [IPR001593]", "Ribosomal protein S4/S9 [IPR022801]", "Ribosomal protein S4/S9, eukaryotic/archaeal [IPR005710]", "Ribosomal protein S4e [IPR000876]", "Ribosomal protein S5 [IPR000851]", "Ribosomal protein S5, eukaryotic/archaeal [IPR005711]", "Ribosomal protein S5/S7 [IPR000235]", "Ribosomal protein S5/S7, eukaryotic/archaeal [IPR005716]", "Ribosomal protein S6 kinase II [IPR016239]", "Ribosomal protein S6, eukaryotic [IPR014401]", "Ribosomal protein S6e [IPR001377]", "Ribosomal protein S7e [IPR000554]", "Ribosomal protein S8 [IPR000630]", "Ribosomal protein S8e [IPR001047]", "Ribosomal protein S8e/ribosomal biogenesis NSA2 [IPR022309]", "Ribosomal protein S9 [IPR000754]", "Ribosome assembly factor Mrt4 [IPR033867]", "Ribosome biogenesis factor, NIP7 [IPR016686]", "Ribosome biogenesis protein BRX1 [IPR026532]", "Ribosome biogenesis protein Bms1/Tsr1 [IPR039761]", "Ribosome biogenesis protein Nop53/GLTSCR2 [IPR011687]", "Ribosome biogenesis protein Rpf2 [IPR039770]", "Ribosome maturation protein Sdo1/SBDS [IPR002140]", "Ribosome maturation protein Sdo1/SBDS-like [IPR039100]", "Ribosome recycling factor [IPR002661]", "Ribosome-binding ATPase YchF/Obg-like ATPase 1 [IPR004396]", "Ribosome-binding protein 1 [IPR040248]", "RidA family [IPR006056]", "Rieske iron-sulphur protein [IPR014349]", "RuvB-like [IPR027238]", "RuvB-like helicase 1 [IPR037938]", "RuvB-like helicase 2 [IPR037942]", "S-adenosylmethionine synthetase [IPR002133]", "S-formylglutathione hydrolase [IPR014186]", "S-phase kinase-associated protein 1 [IPR016897]", "S-phase kinase-associated protein 1-like [IPR001232]", "SAFB-like transcription modulator [IPR034780]", "SCAMP [IPR007273]", "SERRATE/Ars2 [IPR039727]", "SH3 and PX domain-containing protein 2B [IPR030512]", "SH3-binding, glutamic acid-rich protein [IPR006993]", "SHC SH2 domain-binding protein 1-like [IPR045140]", "SIT4 phosphatase-associated protein family [IPR007587]", "SKI-interacting protein, SKIP [IPR017862]", "SLC12A transporter family [IPR004842]", "SNF5/SMARCB1/INI1 [IPR006939]", "SNU66/SART1 family [IPR005011]", "SNX17/27/31 [IPR037831]", "SOS response associated peptidase (SRAP) [IPR003738]", "SOUL haem-binding protein [IPR006917]", "SSNA1 family [IPR033362]", "SUMO-activating enzyme subunit Uba2 [IPR030661]", "SUN domain-containing protein 1 [IPR018539]", "SUN domain-containing protein 1-5 [IPR045119]", "SUN domain-containing protein 2 [IPR030272]", "SURP and G-patch domain-containing protein 1/2 [IPR040169]", "SWI/SNF complex subunit BAF57 [IPR030089]", "SWI/SNF complex subunit BRG1 [IPR030100]", "SWI/SNF complex subunit SMARCC1 [IPR030087]", "SWI/SNF complex subunit SMARCC2 [IPR038044]", "SWI/SNF-like complex subunit BAF250a [IPR030094]", "SWI/SNF-like complex subunit BAF250/Osa [IPR021906]", "SWR1-complex protein 4/DNA methyltransferase 1-associated protein 1 [IPR027109]", "SWR1-complex protein 5/Craniofacial development protein 1/2 [IPR027124]", "Saf4/Yju2 protein [IPR007590]", "Saposin [IPR008373]", "Saposin, chordata [IPR021165]", "Scaffold attachment factor B1 [IPR034781]", "Scaffold attachment factor B2 [IPR034782]", "Scavenger mRNA decapping enzyme DcpS/DCS2 [IPR008594]", "Scc2/Nipped-B family [IPR033031]", "Schlafen family [IPR029684]", "Sda1 [IPR027312]", "Sdc1/DPY30 [IPR037856]", "Sec1-like protein [IPR001619]", "Sec13/Seh1 family [IPR037363]", "Sec20 [IPR005606]", "SecY/SEC61-alpha family [IPR002208]", "Selenium-binding protein [IPR008826]", "Selenophosphate synthetase [IPR004536]", "Sentrin-specific protease 3 [IPR037945]", "Sepiapterin reductase [IPR006393]", "Septin 2 [IPR008113]", "Septin 6 [IPR030644]", "Septin 7 [IPR008115]", "Septin 9 [IPR030645]", "Septin [IPR016491]", "Septin and tuftelin interacting protein [IPR024933]", "Serine hydroxymethyltransferase [IPR001085]", "Serine-tRNA ligase, type1 [IPR002317]", "Serine/arginine-rich splicing factor 10 [IPR034476]", "Serine/arginine-rich splicing factor 11 [IPR034447]", "Serine/arginine-rich splicing factor 2-like [IPR034893]", "Serine/arginine-rich splicing factor 6 [IPR029541]", "Serine/threonine protein phosphatase 5 [IPR011236]", "Serine/threonine-protein kinase MARK1 [IPR033627]", "Serine/threonine-protein kinase MRCK beta [IPR033232]", "Serine/threonine-protein kinase OSR1 [IPR028749]", "Serine/threonine-protein kinase PAK2 [IPR035065]", "Serine/threonine-protein kinase RAC alpha [IPR039027]", "Serine/threonine-protein kinase TOR [IPR026683]", "Serine/threonine-protein kinase Vps15-like [IPR045162]", "Serine/threonine-protein phosphatase 2A subunit A, metazoa [IPR031090]", "Serine/threonine-protein phosphatase 4 regulatory subunit 1 [IPR031087]", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit [IPR037979]", "Serpin H1 [IPR033547]", "Serpin family [IPR000215]", "Shootin-1 [IPR024849]", "Short transmembrane mitochondrial protein 1 [IPR027854]", "Short-chain dehydrogenase/reductase SDR [IPR002347]", "Sideroflexin-4 [IPR028825]", "Sigma intracellular receptor 2 [IPR016964]", "Signal peptidase complex catalytic subunit SEC11A [IPR037712]", "Signal peptidase complex subunit Spc2/SPCS2 [IPR009582]", "Signal recognition particle SRP9 [IPR039914]", "Signal recognition particle receptor, beta subunit [IPR019009]", "Signal recognition particle subunit SRP68 [IPR026258]", "Signal recognition particle, SRP14 subunit [IPR003210]", "Signal recognition particle, SRP19 subunit [IPR002778]", "Signal recognition particle, SRP54 subunit [IPR022941]", "Signal recognition particle, SRP54 subunit, eukaryotic [IPR006325]", "Signal recognition particle, SRP72 subunit [IPR026270]", "Signal recognition particle, SRP9 subunit [IPR008832]", "Sin3 associated polypeptide p18 [IPR010516]", "Single-stranded DNA-binding protein [IPR011344]", "Sirtuin family [IPR003000]", "Sister chromatid cohesion protein Pds5 [IPR039776]", "Ski3/TTC37 [IPR039226]", "Sla2 family [IPR030224]", "Sm-like protein Lsm6/SmF [IPR016487]", "Smac/DIABLO protein [IPR015142]", "Small (40S) ribosomal subunit Asc1/RACK1 [IPR045223]", "Small GTPase Rho [IPR003578]", "Small GTPase [IPR001806]", "Small GTPase superfamily, ARF type [IPR024156]", "Small GTPase superfamily, ARF/SAR type [IPR006689]", "Small GTPase superfamily, SAR1-type [IPR006687]", "Small GTPase, Ras-type [IPR020849]", "Small nuclear ribonucleoprotein E [IPR027078]", "Small nuclear ribonucleoprotein Sm D2 [IPR027248]", "Small nuclear ribonucleoprotein Sm D3 [IPR034099]", "Small-subunit processome, Utp11 [IPR007144]", "Small-subunit processome, Utp14 [IPR006709]", "Smg8/Smg9 [IPR019354]", "Smooth muscle protein/calponin [IPR003096]", "Snf7 family [IPR005024]", "Sodium/potassium-transporting ATPase subunit beta [IPR000402]", "Sodium/potassium-transporting ATPase subunit beta, chordates [IPR015565]", "Sodium:dicarboxylate symporter [IPR001991]", "Sodium:neurotransmitter symporter [IPR000175]", "Solute carrier family 12 member 1/2 [IPR002443]", "Solute carrier family 12 member 2 [IPR002444]", "Solute carrier family 35 member SLC35F1/F2/F6 [IPR009262]", "Sorbitol dehydrogenase-like [IPR045306]", "Sorting nexin 9 family [IPR014536]", "Sorting nexin-1 [IPR028660]", "Sorting nexin-17 [IPR028666]", "Sorting nexin-2 [IPR028653]", "Sorting nexin-27 [IPR028667]", "Sorting nexin-4 [IPR034783]", "Sorting nexin-5 [IPR028654]", "Sorting nexin-5/6/32 [IPR014637]", "Sorting nexin-6 [IPR028657]", "Sorting nexin-9 [IPR028644]", "Spartin-like [IPR045036]", "Spectrin, beta subunit [IPR016343]", "Spermatid perinuclear RNA-binding protein [IPR030446]", "Spermidine/spermine synthase, eukaryotes [IPR030668]", "Spermidine/spermine synthases [IPR001045]", "Spermine synthase, animal [IPR015576]", "Sphingomyelin phosphodiesterase 4 [IPR024129]", "Sphingosine N-acyltransferase Lag1/Lac1-like [IPR016439]", "Spindle and kinetochore-associated protein 1 [IPR009829]", "Spindle and kinetochore-associated protein 3 [IPR033341]", "Spindle assembly checkpoint component Mad1 [IPR008672]", "Splicing factor 3A subunit 1 [IPR045146]", "Splicing factor 3A subunit 3 [IPR031776]", "Splicing factor 3B subunit 1-like [IPR038737]", "Splicing factor 3B subunit 5/RDS3 complex subunit 10 [IPR009846]", "Splicing factor 3B, subunit 5 [IPR017089]", "Splicing factor 45 [IPR040052]", "Splicing factor ELAV/Hu [IPR006548]", "Splicing factor Yju2 [IPR043701]", "Splicing factor, RBM39-like [IPR006509]", "Splicing factor, arginine/serine-rich 19 [IPR042841]", "Squalene cyclase [IPR018333]", "Squalene monooxygenase [IPR040125]", "Squalene synthase-like [IPR006449]", "Squalene/phytoene synthase [IPR002060]", "Stathmin family [IPR000956]", "Sterol O-acyltransferase, ACAT/DAG/ARE types [IPR014371]", "Sterol O-acyltransferase, metazoa [IPR030687]", "Sterol transport protein NPC2-like [IPR039670]", "Stomatin [IPR028515]", "Stomatin/HflK/HflC family [IPR001972]", "Structural maintenance of chromosomes flexible hinge domain-containing protein 1 [IPR038892]", "Structural maintenance of chromosomes protein 1A, metazoan [IPR029683]", "Structural maintenance of chromosomes protein [IPR024704]", "Structure-specific recognition protein [IPR000969]", "Succinate dehydrogenase, flavoprotein subunit [IPR011281]", "Succinate dehydrogenase/fumarate reductase iron-sulphur protein [IPR004489]", "Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [IPR014006]", "Succinate semialdehyde dehydrogenase [IPR010102]", "Succinate--CoA synthetase, beta subunit [IPR005809]", "Succinyl-CoA ligase, alpha subunit [IPR005810]", "Sulfhydryl oxidase [IPR039798]", "Sulfotransferase [IPR005331]", "Sulfurtransferase TST/MPST-like [IPR045078]", "Suppressor of white apricot [IPR040397]", "Surface antigen D15-like [IPR039910]", "Surfeit locus 6 [IPR007019]", "Symplekin/Pta1 [IPR021850]", "Synaptobrevin [IPR001388]", "Synaptogyrin [IPR016579]", "Syntaxin [IPR045242]", "Syntenin-1 [IPR030528]", "Synthesis of cytochrome c oxidase, Sco1/Sco2 [IPR017276]", "T-complex 11 [IPR008862]", "T-complex protein 1, alpha subunit [IPR012715]", "T-complex protein 1, beta subunit [IPR012716]", "T-complex protein 1, delta subunit [IPR012717]", "T-complex protein 1, epsilon subunit [IPR012718]", "T-complex protein 1, eta subunit [IPR012720]", "T-complex protein 1, gamma subunit [IPR012719]", "T-complex protein 1, theta subunit [IPR012721]", "T-complex protein 1, zeta subunit [IPR012722]", "TACC family [IPR039915]", "TAF15/EWS/TLS family [IPR034870]", "TANGO6/Rtp1 [IPR039600]", "TAP46-like protein [IPR007304]", "TATA binding associated factor 15 [IPR034875]", "TATA element modulatory factor 1 DNA binding [IPR022092]", "TB2/DP1/HVA22-related protein [IPR004345]", "TE2IP/Rap1 [IPR039595]", "TEL2-interacting protein 1 [IPR016441]", "TFP11/STIP/Ntr1 [IPR045211]", "TH1 protein [IPR006942]", "THO complex subunit 2 [IPR040007]", "THO complex subunit 6 [IPR042626]", "THO complex, subunit 5 [IPR019163]", "THO complex, subunit THOC1 [IPR021861]", "THRAP3/BCLAF1 family [IPR029199]", "THUMP domain-containing protein 1-like [IPR040183]", "TMEM192 family [IPR029399]", "TMEM206 protein [IPR029366]", "TMEM33/Pom33 family [IPR005344]", "TOX high mobility group box family member 4 [IPR037985]", "TPMT family [IPR008854]", "TPP-binding domain containing protein HACL1-like [IPR045025]", "TPX2 [IPR009675]", "TRAPP I complex, subunit 5 [IPR016696]", "TREX component Tex1/THOC3 [IPR040132]", "Tankyrase 1-binding protein-like [IPR040006]", "Target of Myb protein 1 [IPR014645]", "TatSF1-like [IPR034393]", "Taxilin family [IPR026183]", "Telomerase RNA component interacting RNase [IPR038838]", "Telomere-associated protein Rif1 [IPR028566]", "Telomeric repeat-binding factor 1/2 [IPR017357]", "Telomeric repeat-binding factor 2 [IPR030657]", "Testin [IPR027683]", "Testis-expressed protein 10/pre-rRNA-processing protein Ipi1 [IPR037947]", "Tetrahydrofolate dehydrogenase/cyclohydrolase [IPR000672]", "Tetraspanin, animals [IPR000301]", "Tetraspanin/Peripherin [IPR018499]", "Tetratricopeptide repeat protein 19 [IPR040395]", "Tetratricopeptide repeat protein 26 [IPR030511]", "Tetratricopeptide repeat protein 38 [IPR033891]", "Tetratricopeptide repeat protein TTC27/Emw1 [IPR044244]", "The Golgi pH regulator/GPCR-type G protein [IPR015672]", "ThiF/MoeB/HesA family [IPR045886]", "Thiamine pyrophosphate enzyme [IPR045229]", "Thiolase [IPR002155]", "Thiopurine S-methyltransferase [IPR025835]", "Thioredoxin [IPR005746]", "Thioredoxin domain-containing protein 17-like [IPR045108]", "Thioredoxin-related transmembrane protein 2 [IPR039101]", "Thioredoxin/glutathione reductase selenoprotein [IPR006338]", "Threonine-tRNA ligase, class IIa [IPR002320]", "Thymidine kinase [IPR001267]", "Thymidylate kinase [IPR018094]", "Thymidylate synthase [IPR000398]", "Thymidylate synthase/dCMP hydroxymethylase [IPR045097]", "Thyroid hormone receptor-associated protein 3 [IPR026667]", "Tight junction protein ZO [IPR005417]", "Tight junction protein ZO-1 [IPR005418]", "Tight junction protein ZO-2 [IPR005419]", "Tim23-like [IPR045238]", "Tim44-like [IPR039544]", "Timeless [IPR044998]", "Tissue alpha-L-fucosidase [IPR028755]", "TmcA/NAT10/Kre33 [IPR032672]", "Tom40 [IPR037930]", "Torsin 1/2 [IPR017378]", "Torsin [IPR010448]", "Torsin-1A-interacting protein 1/2 [IPR008662]", "Torsin-1B [IPR030550]", "TraB/PrgY/GumN family [IPR002816]", "Trafficking protein particle complex subunit [IPR007233]", "Trans-isoprenyl diphosphate synthases, eukaryotic-type [IPR044844]", "Transaldolase type 1 [IPR004730]", "Transaldolase/Fructose-6-phosphate aldolase [IPR001585]", "Transcription elongation factor SPT5 [IPR039659]", "Transcription elongation factor Spt5, eukaryote [IPR017071]", "Transcription elongation factor Spt6 [IPR017072]", "Transcription elongation factor, IIS-type [IPR035100]", "Transcription elongation factor, TFIIS [IPR006289]", "Transcription elongation regulator 1-like [IPR045148]", "Transcription facto Tfc3-like [IPR044210]", "Transcription factor BTF3 [IPR039370]", "Transcription factor II-I [IPR016659]", "Transcription factor IIIC subunit Tfc1/Sfc1 [IPR040454]", "Transcription factor STAT [IPR001217]", "Transcription factor TFIIB [IPR000812]", "Transcription factor Tfc4/TFIIIC-102/Sfc4 [IPR039340]", "Transcription initiation factor IIF, alpha subunit [IPR008851]", "Transcription initiation factor IIF, beta subunit [IPR003196]", "Transcription intermediary factor 1-beta [IPR037373]", "Transcription termination factor, mitochondrial/chloroplastic [IPR003690]", "Transcriptional regulator TACO1-like [IPR002876]", "Transcriptional regulatory protein Sin3-like [IPR039774]", "Transcriptional regulatory protein Sin3a [IPR037969]", "Transcriptional repressor p66 [IPR040386]", "Transducin beta-like protein 2 [IPR042410]", "Transferrin receptor protein 1 [IPR029513]", "Transgelin-2 [IPR001061]", "Translation Initiation factor eIF- 4e [IPR001040]", "Translation elongation factor EF1A, eukaryotic/archaeal [IPR004539]", "Translation elongation factor EFG/EF2 [IPR004540]", "Translation elongation factor EFTs/EF1B [IPR001816]", "Translation elongation factor EFTu/EF1A, bacterial/organelle [IPR004541]", "Translation elongation factor IF5A-like [IPR001884]", "Translation initiation factor 2, alpha subunit [IPR011488]", "Translation initiation factor 2A [IPR011387]", "Translation initiation factor 3 complex subunit L [IPR019382]", "Translation initiation factor IF- 2 [IPR015760]", "Translation initiation factor IF2/IF5 [IPR045196]", "Translation initiation factor IF6 [IPR002769]", "Translation initiation factor aIF-2, bacterial-like [IPR000178]", "Translation machinery associated TMA7 [IPR015157]", "Translation machinery-associated protein 16 [IPR021346]", "Translation release factor pelota [IPR004405]", "Translational activator Gcn1 [IPR033173]", "Translationally controlled tumour protein [IPR018105]", "Translin [IPR033956]", "Translin family [IPR002848]", "Translocation associated membrane protein [IPR016447]", "Translocation protein Sec62 [IPR004728]", "Translocation protein Sec63 [IPR027137]", "Translocator protein [IPR030164]", "Translocon-associated [IPR008855]", "Translocon-associated protein (TRAP), alpha subunit [IPR005595]", "Transmembrane emp24 domain-containing protein 5 [IPR015717]", "Transmembrane emp24 domain-containing protein 7 [IPR015718]", "Transmembrane emp24 domain-containing protein [IPR015720]", "Transmembrane protein 109 [IPR039492]", "Transmembrane protein 11 [IPR026120]", "Transmembrane protein 126 [IPR009801]", "Transmembrane protein 160 [IPR026801]", "Transmembrane protein 201 [IPR040041]", "Transmembrane protein 205 [IPR042623]", "Transmembrane protein 214 [IPR019308]", "Transmembrane protein 230 [IPR044234]", "Transmembrane protein 230/134 [IPR008590]", "Transmembrane protein 43 family [IPR012430]", "Transmembrane protein GPR107/GPR108-like [IPR009637]", "Transmembrane protein TqsA-like [IPR002549]", "Transport protein particle (TRAPP) component [IPR007194]", "Treacle protein [IPR017859]", "Tricarboxylate/iron carrier [IPR004686]", "Trimethyllysine dioxygenase [IPR012776]", "Triosephosphate isomerase [IPR000652]", "Triosephosphate isomerase, bacterial/eukaryotic [IPR022896]", "Trm112-like [IPR005651]", "Tropomodulin [IPR004934]", "Tropomodulin-1 [IPR030135]", "Tropomodulin-3 [IPR030133]", "Tropomyosin [IPR000533]", "Tryptophan-tRNA ligase [IPR002306]", "Tryptophan-tRNA ligase, bacterial-type [IPR024109]", "TspO/MBR-related protein [IPR004307]", "Tuberin [IPR003913]", "Tuberin/Ral GTPase-activating protein subunit alpha [IPR027107]", "Tubulin [IPR000217]", "Tubulin binding cofactor A [IPR004226]", "Tubulin--tyrosine ligase-like protein 12 [IPR027749]", "Tubulin-folding cofactor D [IPR033162]", "Tubulin-specific chaperone C [IPR027684]", "Tubulin-specific chaperone E [IPR044994]", "Tubulin-tyrosine ligase/Tubulin polyglutamylase [IPR004344]", "Tumour protein D52 [IPR007327]", "Tweety [IPR006990]", "Twinfilin [IPR028458]", "Twinkle-like protein [IPR027032]", "Type 1 protein exporter [IPR039421]", "Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase [IPR002591]", "Type II pantothenate kinase [IPR004567]", "Type II phosphatidylinositol 4-kinase Lsb6/PI4K2 [IPR039756]", "Tyrosine protein kinase, EGF/ERB/XmrK receptor [IPR016245]", "Tyrosine-protein kinase, insulin-like receptor [IPR016246]", "Tyrosine-tRNA ligase [IPR002307]", "Tyrosine-tRNA ligase, bacterial-type [IPR024088]", "U1 small nuclear ribonucleoprotein C [IPR017340]", "U2 auxiliary factor small subunit [IPR009145]", "U2 small nuclear ribonucleoprotein A' [IPR044640]", "U2 snRNP auxilliary factor, large subunit, splicing factor [IPR006529]", "U3 small nucleolar RNA-associated protein 10 [IPR040191]", "U3 small nucleolar RNA-associated protein 18 [IPR045161]", "U3 small nucleolar RNA-associated protein 25 [IPR010678]", "U3 small nucleolar RNA-associated protein 6 [IPR013949]", "U3 small nucleolar ribonucleoprotein complex, subunit Mpp10 [IPR012173]", "U3 snoRNP protein/Ribosome production factor 1 [IPR044281]", "U4/U6 small nuclear ribonucleoprotein Prp3 [IPR027104]", "U4/U6 small nuclear ribonucleoprotein Prp31 [IPR027105]", "U6 snRNA-associated Sm-like protein LSm2 [IPR016654]", "UAA transporter [IPR013657]", "UBAP2/protein lingerer [IPR022166]", "UBX domain-containing protein 2/7 [IPR017346]", "UDP-N-acetylglucosamine 2-epimerase,UDP-hydrolysing [IPR020004]", "UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110kDa subunit [IPR037919]", "UDP-glucose 6-dehydrogenase, eukaryotic type [IPR028356]", "UDP-glucose/GDP-mannose dehydrogenase [IPR017476]", "UDP-glucose:Glycoprotein Glucosyltransferase [IPR009448]", "UDP-sugar pyrophosphorylase [IPR039741]", "UDPGP family [IPR002618]", "UHRF1-binding protein 1-like [IPR026728]", "UHRF1/2-like [IPR045134]", "UMP-CMP kinase [IPR006266]", "UPF0600 protein C5orf51 [IPR037657]", "USP39 [IPR033809]", "UTP--glucose-1-phosphate uridylyltransferase [IPR016267]", "UV excision repair protein Rad23 [IPR004806]", "Ubiquilin-1/2 [IPR028430]", "Ubiquinol-cytochrome-c reductase complex assembly factor 2 [IPR037698]", "Ubiquitin binding protein, Hrs/VPS27 [IPR017073]", "Ubiquitin carboxyl-terminal hydrolase 10 [IPR028767]", "Ubiquitin carboxyl-terminal hydrolase 14-like [IPR044635]", "Ubiquitin conjugation factor E4 [IPR045132]", "Ubiquitin fusion degradation protein Ufd1-like [IPR004854]", "Ubiquitin thioesterase OTUB1 [IPR030298]", "Ubiquitin thioesterase Otubain [IPR016615]", "Ubiquitin-activating enzyme E1 [IPR018075]", "Ubiquitin-like modifier Hub1/Ubl5 [IPR039732]", "Ubiquitin-like-conjugating enzyme Atg3/Atg10 [IPR007135]", "Ubiquitin-protein ligase E3A [IPR017134]", "Ubiquitin-protein ligase E3B/C [IPR044611]", "Ubiquitin-specific peptidase 24 [IPR033382]", "Ubiquitin/SUMO-activating enzyme E1 [IPR000011]", "Ubiquitinyl hydrolase [IPR016652]", "Ubiquitinyl hydrolase, UCH37 type [IPR017390]", "Ubiquitously expressed transcript protein UXT [IPR003994]", "Uncharacterised conserved protein UCP013899, metal binding [IPR016617]", "Uncharacterised protein family UPF0449 [IPR028227]", "Uncharacterised protein family UPF0687 [IPR026794]", "Uncharacterised protein family, TMEM59 [IPR022065]", "Uncharacterized protein KIAA2013-like [IPR018795]", "Unconventional myosin-XVIIIa [IPR031244]", "Uridine kinase-like [IPR000764]", "Uridine-cytidine kinase 2 [IPR029925]", "Uroporphyrinogen decarboxylase HemE [IPR006361]", "V-type ATPase, V0 complex, 116kDa subunit family [IPR002490]", "V-type ATP synthase catalytic alpha chain [IPR022878]", "V-type ATP synthase regulatory subunit B/beta [IPR022879]", "V-type ATPase subunit E [IPR002842]", "V0 complex accessory subunit Ac45 [IPR008388]", "VPRBP/DCAF1 family [IPR033270]", "Vacuolar import/degradation protein Vid24 [IPR018618]", "Vacuolar protein sorting protein 26 related [IPR028934]", "Vacuolar protein sorting-associated protein 13 [IPR026847]", "Vacuolar protein sorting-associated protein 29 [IPR028661]", "Vacuolar protein sorting-associated protein 33 [IPR027121]", "Vacuolar protein sorting-associated protein 35 [IPR005378]", "Vacuolar protein sorting-associated protein 4 [IPR031255]", "Vacuolar protein sorting-associated protein 51 [IPR014812]", "Vacuolar protein sorting-associated protein 53 [IPR039766]", "Vacuolar protein sorting-associated protein 9-like [IPR045046]", "Vacuolar protein sorting-associated protein Ist1 [IPR005061]", "Vacuolar protein sorting-associated protein Vta1-like [IPR044538]", "Vacuolar protein-sorting protein Bro1-like [IPR045251]", "Vacuole morphology and inheritance protein 14 [IPR026825]", "Valine-tRNA ligase [IPR002303]", "Vesicle transport protein, Got1/SFT2-like [IPR007305]", "Vesicle-associated membrane-protein-associated protein [IPR016763]", "Vesicle-fusing ATPase [IPR039812]", "Vesicle-trafficking protein Sec22 [IPR044565]", "Vezatin [IPR026858]", "Villin/Gelsolin [IPR007122]", "Vimentin [IPR027699]", "Vinculin [IPR017997]", "Vinculin/alpha-catenin [IPR006077]", "Vitamin K epoxide reductase complex subunit 1 [IPR042406]", "Vitamin K-dependent gamma-carboxylase [IPR007782]", "Voltage-dependent anion-selective channel protein 1 [IPR030270]", "Voltage-dependent anion-selective channel protein 2 [IPR030277]", "Voltage-dependent anion-selective channel protein 3 [IPR030271]", "WASH complex subunit 3 [IPR019309]", "WASH complex, subunit strumpellin [IPR019393]", "WD repeat BOP1/Erb1 [IPR028598]", "WD repeat Prp46/PLRG1-like [IPR045241]", "WD repeat WDR12/Ytm1 [IPR028599]", "WD repeat domain phosphoinositide-interacting protein 2 [IPR032911]", "WD repeat-containing protein 41 [IPR040102]", "WD repeat-containing protein 91 [IPR039724]", "WD repeat-containing protein DCAF7-like [IPR045159]", "WD repeat-containing protein WDR18/Ipi3/RID3 [IPR045227]", "WD repeat-containing protein WDR46/Utp7 [IPR040315]", "WD40 repeat-containing protein SMU1 [IPR045184]", "WDR48/Bun107 [IPR021772]", "WW domain binding protein 11 [IPR019007]", "WW domain-binding protein 2 [IPR033598]", "WW domain-binding protein 2-like [IPR044852]", "Wings apart-like protein [IPR039874]", "Wolframin [IPR026208]", "Wolframin family [IPR026209]", "XAP5 protein [IPR007005]", "XMAP215 family [IPR045110]", "XPG/Rad2 endonuclease [IPR006084]", "YAP-binding/ALF4/Glomulin [IPR013877]", "YEATS [IPR005033]", "YLP motif-containing protein 1 [IPR026314]", "YTH domain containing protein [IPR045168]", "YgfZ/GcvT [IPR045179]", "Yif1 family [IPR005578]", "YjeF N-terminal domain-containing protein NAXE-like [IPR032976]", "YjgF/YER057c/UK114 family [IPR006175]", "Yos1-like [IPR013880]", "ZPR1 family [IPR040141]", "Zinc finger CCHC domain-containing protein 3 [IPR042509]", "Zinc finger CCHC-type and RNA-binding motif-containing protein 1 [IPR044598]", "Zinc finger FYVE domain containing protein, SARA/endofin [IPR035438]", "Zinc finger FYVE domain-containing protein, endofin [IPR017165]", "Zinc finger Ran-binding domain-containing protein 2 [IPR017337]", "Zinc finger protein 622/Rei1/Reh1 [IPR040025]", "Zinc finger protein 638 [IPR033096]", "Zinc transporter Msc2-like [IPR045316]", "cAMP-dependent protein kinase catalytic subunit [IPR044109]", "cAMP-dependent protein kinase regulatory subunit [IPR012198]", "dCTP pyrophosphatase 1 [IPR025984]", "dTDP-4-dehydrorhamnose reductase family [IPR005913]", "eIF-2-alpha kinase Gcn2 [IPR016255]", "hnRNP A2/B1 [IPR034489]", "mRNA 3'-end-processing protein Rna14-like [IPR045243]", "mRNA export factor Gle2/RAE1 [IPR037631]", "mRNA-decapping enzyme subunit 1 [IPR010334]", "p53 tumour suppressor family [IPR002117]", "rRNA biogenesis protein Rrp5 [IPR045209]", "siRNA-mediated silencing protein NRDE-2 [IPR013633]", "tRNA (C5-cytosine) methyltransferase, NCL1 [IPR023270]", "tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 [IPR017423]", "tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit [IPR028884]", "tRNA (guanine-N-7) methyltransferase catalytic subunit Trm8, eukaryote [IPR025763]", "tRNA (guanine-N-7) methyltransferase, Trmb type [IPR003358]", "tRNA (guanine-N1-)-methyltransferase, eukaryotic [IPR007356]", "tRNA (uracil(54)-C(5))-methyltransferase, eukaryotic type [IPR045850]", "tRNA N6-adenosine threonylcarbamoyltransferase Kae1, archaea and eukaryote [IPR034680]", "tRNA guanosine-2'-O-methyltransferase, TRM11 [IPR016691]", "tRNA methyltransferase 10 homologue C [IPR025812]", "tRNA methyltransferase, Trm1 [IPR002905]", "tRNA modification GTPase MnmE [IPR004520]", "tRNA pseudouridine synthase B family [IPR004802]", "tRNA pseudouridine synthase II, TruB [IPR014780]", "tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB [IPR006463]", "tRNA-specific 2-thiouridylase [IPR004506]", "tRNAHis guanylyltransferase Thg1 [IPR007537]"], "available_proteins": ["AAAS", "AACS", "AAGAB", "AAR2", "AARS", "AARS2", "AATF", "ABCB1", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABHD12", "ABHD6", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACADM", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOX1", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL6", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ADA", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFG3L2", "AGAP3", "AGL", "AGPS", "AHCY", "AHCYL1", "AHSA1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP12", "AKAP13", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKT1", "AKT1S1", "ALCAM", "ALDH18A1", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALKBH1", "ALKBH5", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANKLE2", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APC", "APEX1", "API5", "APOO", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFIP1", "ARFIP2", "ARHGAP35", "ARHGAP5", "ARHGDIA", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL6IP5", "ARL8B", "ARMC1", "ARMC6", "ARMC9", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARVCF", "ASAH1", "ASCC1", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD2", "ATAD3A", "ATAD3B", "ATE1", "ATF7IP", "ATG3", "ATG4B", "ATG9A", "ATIC", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATXN2", "ATXN2L", "B3GALT6", "B4GALT1", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAIAP2", "BANF1", "BASP1", "BAX", "BCAP31", "BCAS2", "BCAT2", "BCCIP", "BCL2L13", "BCLAF1", "BDH2", "BICD2", "BIRC6", "BLM", "BLMH", "BLOC1S1", "BLVRA", "BMS1", "BNIP1", "BOD1L1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAT1", "BRCA1", "BRI3BP", "BRIX1", "BROX", "BSG", "BTF3", "BUB1", "BUB1B", "BUD23", "BUD31", "BYSL", "C12orf43", "C12orf73", "C14orf2", "C15orf39", "C19orf25", "C19orf70", "C1QBP", "C1orf122", "C1orf123", "C1orf35", "C1orf50", "C20orf27", "C21orf59", "C2CD5", "C2orf49", "C5orf15", "C5orf51", "CAB39", "CACUL1", "CAD", "CALD1", "CALR", "CALU", "CAND1", "CAND2", "CANX", "CAP1", "CAP2", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASP2", "CASP3", "CAST", "CBL", "CBR1", "CBX3", "CCAR1", "CCAR2", "CCDC124", "CCDC138", "CCDC22", "CCDC43", "CCDC47", "CCDC51", "CCDC6", "CCDC86", "CCDC88A", "CCDC93", "CCDC94", "CCDC97", "CCNA2", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC25C", "CDC37", "CDC42", "CDC42BPB", "CDC45", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK5RAP1", "CDK5RAP3", "CDK6", "CDKAL1", "CDR2L", "CDS2", "CDV3", "CEBPZ", "CECR2", "CENPB", "CENPI", "CENPU", "CEP170", "CEP44", "CEP55", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHCHD4", "CHD1L", "CHD8", "CHERP", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP4A", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHST14", "CHTF8", "CIAPIN1", "CIP2A", "CISD2", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLN6", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTA", "CLTC", "CLU", "CLUH", "CMAS", "CMBL", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNOT1", "CNOT11", "CNOT3", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG2", "COG3", "COG7", "COIL", "COLGALT1", "COMMD1", "COMMD10", "COMMD2", "COMMD7", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "CORO1B", "CORO1C", "COTL1", "COX11", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRNKL1", "CRTAP", "CS", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDP1", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWC15", "CWF19L1", "CXorf57", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAXX", "DBN1", "DBNL", "DCAF1", "DCAF7", "DCAF8", "DCAKD", "DCD", "DCP1A", "DCP1B", "DCPS", "DCTD", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDOST", "DDRGK1", "DDT", "DDX54", "DEK", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHODH", "DHPS", "DHRS1", "DHRS4", "DHRS7", "DHRS7B", "DHX29", "DIABLO", "DIAPH1", "DIAPH3", "DIDO1", "DIEXF", "DIMT1", "DIS3L2", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNA2", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJC10", "DNAJC2", "DNAJC8", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLPP1", "DPH2", "DPH5", "DPM1", "DPP3", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYM", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC4", "EEF1A2", "EEF1E1", "EEF1G", "EFCAB14", "EGFR", "EHBP1", "EHD1", "EHD4", "EHMT2", "EIF2A", "EIF2AK4", "EIF2B1", "EIF2B2", "EIF2B4", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAVL1", "ELL", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP4", "EMC1", "EMC2", "EMC3", "EMC8", "EMD", "EMG1", "ENDOD1", "ENO1", "ENO2", "ENSA", "EPB41", "EPB41L2", "EPB41L5", "EPDR1", "EPHX1", "EPHX2", "EPPK1", "EPRS", "ERAL1", "ERAP1", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ESD", "ESF1", "ESS2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6B", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EXTL3", "EZR", "F11R", "FABP5", "FAH", "FAM114A1", "FAM114A2", "FAM118B", "FAM160A2", "FAM162A", "FAM177A1", "FAM213A", "FAM49B", "FAM50A", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FAU", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FIS1", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNTB", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GALK1", "GALM", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GCAT", "GCFC2", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN4", "GEMIN8", "GET4", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GGT7", "GHDC", "GHITM", "GID4", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GM2A", "GMDS", "GMFB", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNE", "GNG5", "GNL1", "GNL2", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM1", "GOLPH3", "GOLPH3L", "GOLT1B", "GOPC", "GORASP2", "GOT1", "GOT2", "GPAM", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR108", "GPR89B", "GPS1", "GPT2", "GRPEL1", "GRSF1", "GSDME", "GSK3B", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTSE1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAGH", "HARS2", "HAT1", "HAUS1", "HAUS2", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HAX1", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDHD2", "HDHD5", "HEATR1", "HEBP1", "HECTD1", "HEXA", "HEXB", "HEXIM1", "HGH1", "HGS", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPC", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HP1BP3", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA6", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HUS1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IER3IP1", "IFIT5", "IFNGR1", "IFT27", "IGBP1", "IGF1R", "IGF2BP2", "IK", "IKBIP", "ILF3", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPA1", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS12", "INTS13", "INTS14", "INTS3", "INTS7", "INTS9", "IPO4", "IPO5", "IRGQ", "IRS4", "ISCU", "ISG20L2", "ISOC2", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITSN2", "IVD", "JAGN1", "JPT2", "JUP", "KARS", "KDELR1", "KDELR3", "KDM1A", "KDM3B", "KDSR", "KHDRBS1", "KHDRBS3", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1468", "KIAA2013", "KIF14", "KIF15", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF5B", "KIFBP", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LCMT1", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMF2", "LNPEP", "LONP1", "LRPAP1", "LRPPRC", "LRRC41", "LRRC47", "LSM12", "LSM2", "LSM6", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LZIC", "LZTFL1", "LZTS2", "M6PR", "MACF1", "MAD1L1", "MAGED1", "MAGED2", "MAGT1", "MAK16", "MAN1A2", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP4", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCKS", "MARK1", "MARS", "MAT2A", "MAT2B", "MAVS", "MBOAT7", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MDH1", "MDH2", "MDN1", "ME2", "MEAF6", "MECP2", "MED14", "MED16", "MED21", "MED23", "MED24", "MED4", "MEPCE", "METAP1", "METAP2", "METTL1", "METTL16", "METTL3", "MFAP1", "MFF", "MFN1", "MFN2", "MFSD10", "MFSD5", "MGAT1", "MGEA5", "MGST2", "MGST3", "MICALL1", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKRN2", "MLEC", "MMAB", "MMGT1", "MMS19", "MOB4", "MOGS", "MORF4L1", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPST", "MPV17L2", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL22", "MRPL23", "MRPL28", "MRPL3", "MRPL37", "MRPL4", "MRPL40", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL50", "MRPL55", "MRPL9", "MRPS10", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSN", "MTA1", "MTA2", "MTAP", "MTBP", "MTDH", "MTERF3", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR2", "MTOR", "MTR", "MTSS1L", "MTX1", "MTX2", "MTX3", "MVK", "MXRA7", "MYBBP1A", "MYCBP", "MYDGF", "MYEF2", "MYG1", "MYO18A", "NAA10", "NAA15", "NAA16", "NAA35", "NAA40", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCDN", "NCKAP1", "NCLN", "NCSTN", "ND5", "NDC1", "NDC80", "NDRG3", "NDUFA13", "NDUFA4", "NDUFAF3", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB4", "NDUFB6", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEFL", "NEFM", "NELFB", "NELFCD", "NELFE", "NES", "NFKB1", "NFS1", "NHP2", "NIP7", "NIPBL", "NLN", "NMD3", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL9", "NOP14", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRDE2", "NSA2", "NSF", "NSMCE2", "NSUN2", "NSUN5", "NSUN6", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUB1", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT21", "NUDT9", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "OAT", "OCIAD1", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAIP2", "PAK2", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PATL1", "PAXIP1", "PBDC1", "PBRM1", "PC", "PCBD1", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNP", "PCNT", "PCYOX1", "PDAP1", "PDCD11", "PDCD5", "PDCD6IP", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDS5A", "PDS5B", "PDXDC1", "PDXK", "PDZD8", "PEBP1", "PECR", "PELO", "PES1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN1", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGGT1B", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PHAX", "PHB", "PHB2", "PHF10", "PHF5A", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PI4KB", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIK3C2A", "PIK3C3", "PIK3R4", "PIN4", "PIP4K2B", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PKM", "PLA2G15", "PLBD2", "PLCB3", "PLCG1", "PLEC", "PLIN3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNISR", "PNKP", "PNN", "PNO1", "PNP", "PNPO", "PNPT1", "POFUT1", "POLA1", "POLA2", "POLD1", "POLD2", "POLE", "POLE2", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPFIA1", "PPHLN1", "PPIE", "PPIH", "PPIL1", "PPIL3", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1R12A", "PPP2R1A", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R2", "PPP5C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKAR2B", "PRKCD", "PRKCSH", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF40A", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPH", "PTBP1", "PTBP2", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPA", "PTPN1", "PTPN11", "PTPN23", "PTRH2", "PTRHD1", "PUF60", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "PYM1", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABEP1", "RABGAP1", "RABGGTA", "RABGGTB", "RABL6", "RAC1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANGRF", "RAP1GDS1", "RAPGEF2", "RAPGEF6", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBM10", "RBM17", "RBM22", "RBM26", "RBM27", "RBM39", "RBM47", "RBM5", "RBM8A", "RCC2", "RCL1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "RECQL5", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "RETREG3", "REXO2", "REXO4", "RFC1", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOX1", "RIOX2", "RMND5A", "RNASEH2A", "RNASEH2B", "RNASET2", "RNF14", "RNF20", "RNF219", "RNF40", "RNPEP", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RPUSD2", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RTCA", "RTCB", "RTFDC1", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SAE1", "SAFB", "SAFB2", "SAMM50", "SAP130", "SAP18", "SAR1A", "SAR1B", "SARS", "SARS2", "SART1", "SBDS", "SBNO1", "SCAF1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCD", "SCFD1", "SCO1", "SCO2", "SCPEP1", "SCRN1", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD7", "SF1", "SF3A1", "SF3A3", "SF3B1", "SF3B5", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SH3BGRL", "SH3BGRL2", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIN3A", "SIRT1", "SKA1", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A22", "SLC25A24", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A40", "SLC25A5", "SLC25A6", "SLC27A4", "SLC30A7", "SLC35A4", "SLC35B2", "SLC35F2", "SLC3A2", "SLC6A15", "SLC9A3R1", "SLFN11", "SLK", "SLTM", "SLU7", "SMARCA4", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMCHD1", "SMG8", "SMPD4", "SMS", "SMU1", "SND1", "SNRPA1", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX4", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SPAG9", "SPART", "SPC24", "SPC25", "SPCS2", "SPDL1", "SPECC1L", "SPNS1", "SPOUT1", "SPPL2A", "SPR", "SPTBN1", "SPTBN2", "SQLE", "SRFBP1", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPRB", "SRRT", "SRSF10", "SRSF11", "SRSF2", "SRSF6", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAT1", "STAT3", "STIP1", "STMN1", "STOM", "STOML2", "STRBP", "STT3A", "STT3B", "STUB1", "STX12", "STX4", "STX6", "STX7", "STX8", "STXBP2", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SURF6", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "TAB1", "TACC3", "TACO1", "TADA3", "TAF15", "TAGLN2", "TALDO1", "TAMM41", "TANGO6", "TAP1", "TARS", "TARS2", "TARSL2", "TBCA", "TBCC", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TCP11L1", "TECR", "TERF2", "TERF2IP", "TES", "TEX10", "TFB1M", "TFG", "TFIP11", "TFRC", "TGS1", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "TIGAR", "TIMELESS", "TIMM17A", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TJP1", "TJP2", "TK1", "TKFC", "TM9SF2", "TM9SF3", "TM9SF4", "TMA16", "TMA7", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM11", "TMEM126A", "TMEM126B", "TMEM160", "TMEM165", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM206", "TMEM209", "TMEM214", "TMEM230", "TMEM245", "TMEM30A", "TMEM33", "TMEM43", "TMEM59", "TMEM63A", "TMEM87A", "TMEM97", "TMF1", "TMLHE", "TMOD1", "TMOD3", "TMX2", "TNKS1BP1", "TNPO1", "TOE1", "TOM1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOP1", "TOP2A", "TOP2B", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TOX4", "TP53", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPMT", "TPP2", "TPT1", "TPX2", "TRABD", "TRAM1", "TRAP1", "TRAPPC4", "TRAPPC5", "TRIM28", "TRIO", "TRIP12", "TRIP13", "TRIR", "TRMT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMU", "TROVE2", "TRUB1", "TSC2", 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sha256:880cbd2153be57f6c51f9fc4406b90c6e217f3aa4d4c38fbb04449d551a4b1ba +size 142319 diff --git a/interpro_homologous_superfamily/consensus.joblib b/interpro_homologous_superfamily/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..a295ac18d1db6b67f5dd88dcfdf4807955445a49 --- /dev/null +++ b/interpro_homologous_superfamily/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c266a83093296191485442a9fed53e4cdfdf9e823137b17dd4d205c6e6e7950a +size 154802 diff --git a/interpro_homologous_superfamily/df_merge.tsv b/interpro_homologous_superfamily/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..fed8b3b093e3bf04579da8a20ff9b4bd65d57b27 --- /dev/null +++ b/interpro_homologous_superfamily/df_merge.tsv @@ -0,0 +1,4 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Mitochondrial carrier domain superfamily [IPR023395] 8 20 3.064744677101647 0.0021785589299352 9.148058252427184 20.71359223300971 2.0411027534642088 0.1411881998864352 5.368907349966936 1.8276489510009888 1.309103123363054 0.2428184236965967 1.141599058742867e-05 0.0008295914112261 3.035452872698047e-05 0.0002799919034951 6.734850608491655e-05 +Nucleophile aminohydrolases, N-terminal [IPR029055] 9 19 2.912154775150172 0.0035894472954138 6.097087378640777 17.820388349514563 1.118176330768516 0.343571999079937 2.960138290874742 0.7151426259133536 1.128434210928413 0.3328142150103464 0.0166138820171136 1.0 0.02421661276018 2.340849497796301e-05 1.1894208847796684e-07 +Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400] 3 5 2.1224466154658232 0.0338002511723951 2.813106796116505 6.104368932038835 1.6405397264547834 0.1100883340733615 1.2852875686886795 0.8042848477475721 1.100790504333474 0.1612592696854457 0.0039071928268104 0.0573151884822011 0.0057815105752346 0.0001450038876457 0.0020333503076747 diff --git a/interpro_homologous_superfamily/metrics.json b/interpro_homologous_superfamily/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..717e5164191898da541e5ba96fa91c3abfbde6e0 --- /dev/null +++ b/interpro_homologous_superfamily/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3329, + "annotations_size": 993, + "title": "Average number of proteins per term", + "value": 4.910372608257805 +} \ No newline at end of file diff --git a/interpro_homologous_superfamily/paths.json b/interpro_homologous_superfamily/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..3810f48fab17be3824468995fe2ee36244e4345a --- /dev/null +++ b/interpro_homologous_superfamily/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_homologous_superfamily/fragment/C342/C342_val_log2fc"} \ No newline at end of file diff --git a/interpro_homologous_superfamily/result.tsv b/interpro_homologous_superfamily/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..3401b7ee12d4dbd93a76cc504774ed894a8f1ba5 --- /dev/null +++ b/interpro_homologous_superfamily/result.tsv @@ -0,0 +1,110 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mitochondrial carrier domain superfamily [IPR023395] 0.7748299248894673 3.064744677101647 0.0021785589299352 0.8853267952297573 0.1175557527644471 20 Q9BSK2,Q9H2D1,Q9Y619,P12235,Q02978,O43772,Q70HW3,Q9Y6C9 8 +Nucleophile aminohydrolases, N-terminal [IPR029055] 0.7538197380394851 2.9121547751501717 0.0035894472954138 0.9718647906406978 0.1175557527644471 19 P28070,Q9UJ14,P25786,P60900,P20618,Q06210,P28074,P49721,P28072 9 +Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400] 0.9042777294053956 2.1224466154658232 0.0338002511723951 0.9999999999999986 0.2179457754168077 5 O43169,O15173,Q9UMX5 3 +Alpha/Beta hydrolase fold [IPR029058] 0.5489281469010213 1.940133266080464 0.0523634961025918 1.0 0.2666510339993522 26 P50897,P07099,Q9NUJ1,Q9HB40,Q9UMR5,P42785,Q96DG6,Q8NCC3,Q9H3G5,P10619,Q8N2K0 11 +Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097] 0.8469948171244304 1.897298412488972 0.0577885644030908 1.0 0.2773389286442119 5 P55786,Q9UIQ6,Q9NZ08 3 +Peptidase M4/M1, CTD superfamily [IPR027268] 0.8469948171244304 1.897298412488972 0.0577885644030908 1.0 0.2773389286442119 5 P55786,Q9UIQ6,Q9NZ08 3 +Haem oxygenase-like, multi-helical [IPR016084] 0.9843703035767944 1.8880400209766384 0.0590205778978827 1.0 0.2798288068655231 2 P30519 1 +Metallopeptidase, catalytic domain superfamily [IPR024079] 0.8131768953068622 1.7620791646762248 0.0780559230187645 1.0 0.3229563814901381 5 P42892,Q9BYT8,P78536,Q99797 4 +Porin domain superfamily [IPR023614] 0.9049166997075976 1.7496222942000552 0.0801835101580956 1.0 0.3273563271860495 4 P21796 1 +Zinc finger, RanBP2-type superfamily [IPR036443] 0.6735948006834193 1.7417763447567731 0.0815475874809328 1.0 0.3291737982462044 9 Q01844,Q92804,P35637 3 +Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid [IPR008930] 0.8965413533834592 1.717703718323605 0.085850670800871 1.0 0.3398643472043905 4 P53609,P48449,P49356 3 +Glutathione S-transferase, C-terminal domain superfamily [IPR036282] 0.5468886767725166 1.702222613496118 0.0887136451950119 1.0 0.3427729559480421 19 O15217 1 +MFS transporter superfamily [IPR036259] 0.7486610411642286 1.6156745128395702 0.1061647042825097 1.0 0.3730752467493172 6 Q6NT16 1 +Glycoside hydrolase superfamily [IPR017853] 0.550979417189136 1.5520945800571555 0.1206395946619052 1.0 0.3993170583309063 16 Q9BTY2,O60502,P06280,Q04446,P54802,P04062 6 +Acyl-CoA N-acyltransferase [IPR016181] 0.6225772047296773 1.5224787565185047 0.1278891643379389 1.0 0.4078776284734553 10 O60502 1 +P-type ATPase, transmembrane domain superfamily [IPR023298] 0.7539943771241531 1.5218790146467065 0.1280393982865071 1.0 0.4078776284734553 5 Q9NQ11,Q9HD20 2 +P-type ATPase, cytoplasmic domain N [IPR023299] 0.7539943771241531 1.5218790146467065 0.1280393982865071 1.0 0.4078776284734553 5 Q9NQ11,Q9HD20 2 +P-type ATPase, A domain superfamily [IPR008250] 0.7539943771241531 1.5218790146467065 0.1280393982865071 1.0 0.4078776284734553 5 Q9NQ11,Q9HD20 2 +GMP phosphodiesterase, delta subunit superfamily [IPR037036] 0.8893898406973129 1.4994376476561837 0.1337601330322859 1.0 0.417684943714025 2 A6NIH7 1 +FAD/NAD(P)-binding domain superfamily [IPR036188] 0.5145859530301564 1.4385412095569203 0.150280553609206 1.0 0.445458476817736 18 Q14534,O95831,Q96CU9,Q9UHG3,Q16134,O60341,Q8NB78 7 +Thioredoxin-like superfamily [IPR036249] 0.4125774416734905 1.3852671892934485 0.1659707825203296 1.0 0.4818976229318341 54 O15217,P78417,Q9H1E5,O43396,Q6DKJ4,Q8N983,P30048,O94888,O95881,Q9H2J4,O75880 11 +NAP-like superfamily [IPR037231] 0.7996030031393077 1.344671486974774 0.1787313463999762 1.0 0.4974362987494622 4 Q01105,Q99733 2 +GYF-like domain superfamily [IPR035445] 0.8512173128944887 1.3427974854355331 0.1793375578573086 1.0 0.4974362987494622 2 O95400 1 +C-type lectin-like/link domain superfamily [IPR016186] 0.8452058911932679 1.3181853372386925 0.1874416127352818 1.0 0.5030527606652293 2 Q9UBG0 1 +C-type lectin fold [IPR016187] 0.8452058911932679 1.3181853372386925 0.1874416127352818 1.0 0.5030527606652293 2 Q9UBG0 1 +K Homology domain, type 1 superfamily [IPR036612] 0.4546635701847248 1.3010523831852383 0.1932405250059941 1.0 0.5160835134792225 28 P51116,P61978,O75525,Q92945,Q96AE4,Q96I24,Q06787,P51114,Q9Y2W6 9 +EF-hand domain pair [IPR011992] 0.4008037964931448 1.2988741132186667 0.1939871348920425 1.0 0.5164322384659471 57 Q9Y680,Q02818,Q66K14,Q0IIM8,Q9H8M7,Q96D71,O43852,P80303,Q96AY3,Q14257,Q9NWM8,O75340,O75071,P0DP25 14 +HAD superfamily [IPR023214] 0.4700284668304813 1.2501596633166223 0.2112412284362672 1.0 0.5359781204723701 21 Q969T7,Q9H0P0,Q9HD20 3 +HAD-like superfamily [IPR036412] 0.4700284668304813 1.2501596633166223 0.2112412284362672 1.0 0.5359781204723701 21 Q969T7,Q9H0P0,Q9HD20 3 +Prefoldin [IPR009053] 0.6208663723369009 1.2269959177919518 0.2198241252344748 1.0 0.551533266930723 7 Q9UBK9,Q9UHV9,O60925 3 +L27 domain superfamily [IPR036892] 0.762646733812635 1.201799560673226 0.2294411957283308 1.0 0.5670771068782579 4 Q14168 1 +Methylthiotransferase, N-terminal domain superfamily [IPR038135] 0.8151487826870957 1.1955907587819083 0.2318562994889956 1.0 0.5670771068782579 2 Q5VV42 1 +Radical SAM, alpha/beta horseshoe [IPR023404] 0.8151487826870957 1.1955907587819083 0.2318562994889956 1.0 0.5670771068782579 2 Q5VV42 1 +Neurolysin/Thimet oligopeptidase, N-terminal [IPR024080] 0.8124436429215461 1.1846071523952353 0.2361728077854452 1.0 0.569311078450995 2 Q9BYT8 1 +Tetraspanin, EC2 domain superfamily [IPR008952] 0.839278149833835 1.1621857678919758 0.2451600144400165 1.0 0.5852016690839817 3 O43657 1 +Immunoglobulin-like domain superfamily [IPR036179] 0.5142066004325474 1.1512489224076006 0.2496298437940103 1.0 0.5916048565332989 13 P10321,P10586,P04439,Q9Y639,P35613 5 +RmlC-like cupin domain superfamily [IPR011051] 0.7488354708454058 1.148533895263421 0.2507482286721916 1.0 0.591945224244678 4 O00625 1 +Cytochrome P450 superfamily [IPR036396] 0.7965133754132685 1.1201479848586229 0.2626507052963229 1.0 0.608900193005287 2 Q16850 1 +Neurolysin/Thimet oligopeptidase, domain 2 [IPR024077] 0.8126879134094951 1.0643896641822015 0.2871522140605016 1.0 0.6195885390126078 3 Q9BYT8,Q99797 2 +Rab-GTPase-TBC domain superfamily [IPR035969] 0.5312892946053379 1.0636311642709708 0.2874958188920247 1.0 0.6195885390126078 10 O60343,Q66K14,Q8TC07,Q0IIM8,Q9BXI6 5 +PX domain superfamily [IPR036871] 0.4973308306280906 1.057033631237736 0.2904962388721606 1.0 0.6195885390126078 13 Q96L92,Q9UMY4,Q9Y2I1 3 +MHC class I-like antigen recognition-like superfamily [IPR037055] 0.8105832832230833 1.056688171025116 0.2906539253341229 1.0 0.6195885390126078 3 P04439,P10321 2 +MHC classes I/II-like antigen recognition protein [IPR011162] 0.8105832832230833 1.056688171025116 0.2906539253341229 1.0 0.6195885390126078 3 P04439,P10321 2 +Ribonucleotide reductase-like [IPR012348] 0.780583107905001 1.0561432992818989 0.2909027508669424 1.0 0.6195885390126078 2 Q7LG56 1 +Ferritin-like superfamily [IPR009078] 0.780583107905001 1.0561432992818989 0.2909027508669424 1.0 0.6195885390126078 2 Q7LG56 1 +Tetratricopeptide-like helical domain superfamily [IPR011990] 0.3650261295103467 1.055082574951524 0.2913875606433915 1.0 0.6195885390126078 88 O15091,O00231,Q9Y3D6,O75153,Q6ZXV5,Q32P28,Q92791,Q9Y262,Q9UBV2,A0AVF1,Q6P2P2,Q13451,Q6DKK2,Q5R3I4,P13674,Q02790,O75718,Q9H0B6,Q6P3X3,Q9UJX4,Q9BZJ0,Q6PGP7,O76024,Q07866,Q9UJX3,O15460 26 +Concanavalin A-like lectin/glucanase domain superfamily [IPR013320] 0.4417148913102804 1.0397823152526402 0.2984410471396956 1.0 0.6201133786265085 20 P49257,P19474 2 +SNARE [IPR010989] 0.634225939559415 1.0285834487686183 0.3036754588427568 1.0 0.6217520219192938 5 Q86Y82,O43752,O15400 3 +Kringle-like fold [IPR013806] 0.7958508719182146 1.0029756496320632 0.3158726101925211 1.0 0.6278683418983123 3 Q9UBG0,P11717 2 +Fibronectin type II domain superfamily [IPR036943] 0.7958508719182146 1.0029756496320632 0.3158726101925211 1.0 0.6278683418983123 3 Q9UBG0,P11717 2 +B30.2/SPRY domain superfamily [IPR043136] 0.4859774049837958 0.9935559714011444 0.3204390882874879 1.0 0.6288458787934298 13 P19474 1 +PABC (PABP) domain [IPR036053] 0.7904389657245894 0.9833405976480414 0.3254398355718244 1.0 0.6305417817418417 3 O95071,P11940 2 +SH3-like domain superfamily [IPR036028] 0.4066801984297539 0.952916145502468 0.3406325589381846 1.0 0.6423261424791571 29 P62993,Q9UQB8,Q92783,P46108,Q14168,Q9NZW5 6 +Pyridoxal phosphate-dependent transferase, small domain [IPR015422] 0.4628627640298656 0.9448465809580294 0.344737206885612 1.0 0.6465336789265124 14 O95470,O15270,P34896 3 +BAG domain superfamily [IPR036533] 0.7790138304269314 0.9420823659718582 0.3461504719695232 1.0 0.6465336789265124 3 O95429,Q9UL15 2 +Pyridoxal phosphate-dependent transferase, major domain [IPR015421] 0.4508607629530795 0.9088468732924536 0.3634309602779337 1.0 0.6596621430011333 15 O95470,O15270,P34896 3 +Pyridoxal phosphate-dependent transferase [IPR015424] 0.4508607629530795 0.9088468732924536 0.3634309602779337 1.0 0.6596621430011333 15 O95470,O15270,P34896 3 +EB1, C-terminal domain superfamily [IPR036133] 0.7388037270814363 0.8913064237680492 0.372764803415448 1.0 0.6622693900588746 2 Q15555 1 +Golgi phosphoprotein 3-like domain superfamily [IPR038261] 0.7351968740607159 0.8773367784311041 0.380303741340074 1.0 0.6622693900588746 2 Q9H4A6 1 +LEM/LEM-like domain superfamily [IPR011015] 0.5497517726172032 0.7796704469000352 0.4355848783710894 1.0 0.6952669452729364 6 Q86XL3 1 +K homology domain superfamily, prokaryotic type [IPR009019] 0.6967237751728278 0.7317808444024629 0.4643023427115615 1.0 0.7147603142395368 2 O75616 1 +K homology domain-like, alpha/beta [IPR015946] 0.6967237751728278 0.7317808444024629 0.4643023427115615 1.0 0.7147603142395368 2 O75616 1 +Six-hairpin glycosidase-like superfamily [IPR012341] 0.7181151365157503 0.7281594289811737 0.4665159980348521 1.0 0.7159975054847112 3 O60476 1 +Glycosyl hydrolase, all-beta [IPR013780] 0.465403768920416 0.715069440896228 0.4745661357512691 1.0 0.7249910350784774 9 P04066,P06280,Q04446,Q9BTY2 4 +Ricin B-like lectins [IPR035992] 0.6105657268704403 0.6341584461622931 0.5259774231140641 1.0 0.7613048428245088 4 Q9UBG0 1 +ABC transporter type 1, transmembrane domain superfamily [IPR036640] 0.5347320263376567 0.630981527554579 0.5280526027815833 1.0 0.7613048428245088 5 Q03518 1 +Translin, N-terminal [IPR016068] 0.6573489630297586 0.5912387555129842 0.5543604587374682 1.0 0.7613048428245088 2 Q15631 1 +Translin, C-terminal [IPR016069] 0.6573489630297586 0.5912387555129842 0.5543604587374682 1.0 0.7613048428245088 2 Q15631 1 +Translin superfamily [IPR036081] 0.6573489630297586 0.5912387555129842 0.5543604587374682 1.0 0.7613048428245088 2 Q15631 1 +Class I glutamine amidotransferase-like [IPR029062] 0.4425007650458791 0.5480909250102658 0.5836294715294392 1.0 0.7765869554689573 8 Q92820,P17812,Q9NRF8 3 +Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily [IPR036940] 0.4904307861052397 0.5418993256364207 0.5878878613598084 1.0 0.7767309357402155 6 P42356 1 +Nucleotide-diphospho-sugar transferases [IPR029044] 0.3631157510252102 0.5408850495258032 0.5885868163246597 1.0 0.7767309357402155 22 Q16739,Q9Y5P6,P46976,Q10471,Q13144,P26572,O43909,Q96IJ6,O60568,P15291 10 +GTP-binding protein TrmE/Aminomethyltransferase GcvT, domain 1 [IPR027266] 0.6509320505111221 0.5105355095471167 0.6096763437489963 1.0 0.7870641360086763 3 Q969Y2,Q5T440 2 +Band 7/SPFH domain superfamily [IPR036013] 0.4284853959650767 0.4855894758295176 0.6272582596353 1.0 0.79888841912314 8 O94905,P35232,Q99623,O75477,O75955,Q9UJZ1,P27105 7 +DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily [IPR037033] 0.60414788097384 0.4204063293832003 0.6741886451188714 1.0 0.8316389125503595 2 P30876 1 +RNA polymerase Rpb2, domain 2 superfamily [IPR037034] 0.60414788097384 0.4204063293832003 0.6741886451188714 1.0 0.8316389125503595 2 P30876 1 +RNA polymerase Rpb2, OB-fold [IPR014724] 0.60414788097384 0.4204063293832003 0.6741886451188714 1.0 0.8316389125503595 2 P30876 1 +AH/BAR domain superfamily [IPR027267] 0.3606626847643345 0.4068541173564987 0.6841151367583718 1.0 0.8346953700568407 16 P53365,Q9UQB8 2 +EXOC6/PINT-1/Sec15/Tip20, C-terminal, domain 2 [IPR042044] 0.586414186955222 0.3695958448078786 0.7116836475824424 1.0 0.8434504091889812 2 Q6NUQ1 1 +Heat shock protein DnaJ, cysteine-rich domain superfamily [IPR036410] 0.5923030667468328 0.3456251747601633 0.7296244239449428 1.0 0.8574166307424002 3 O60884,P31689 2 +14-3-3 domain superfamily [IPR036815] 0.4363526933493882 0.3443635797575755 0.7305728749219027 1.0 0.8575163886494673 6 P61981,P27348,P63104,P62258,Q04917 5 +Dynein light chain superfamily [IPR037177] 0.5716862037872026 0.3300877929867153 0.7413336265801576 1.0 0.8634359729100355 2 Q96FJ2 1 +Tim10-like domain superfamily [IPR035427] 0.585387853277199 0.328149659886454 0.7427985077552739 1.0 0.8634359729100355 3 Q9Y5J9,O60220 2 +AF1104-like superfamily [IPR036075] 0.5704839194469524 0.3269755281669845 0.7436863944695427 1.0 0.8634359729100355 2 Q9H993 1 +Mannose-6-phosphate receptor binding domain superfamily [IPR009011] 0.5782946962176396 0.310707794007214 0.7560227715757175 1.0 0.8721657582878118 3 P20645 1 +Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily [IPR037151] 0.5730607336139388 0.2981593262584581 0.7655815636265411 1.0 0.8798871443068927 3 Q9C0B1,Q6P6C2 2 +RNA-binding domain superfamily [IPR035979] 0.3305010574767125 0.2803920429126949 0.7791767411479253 1.0 0.8854652986411852 134 Q86V81,Q13242,P11940,P55795,Q14103,Q8IZ69,O60506,Q9BWF3,P98175,Q15056,Q8NDT2,O43347,Q8IY67,O43390,P31942,Q9UHX1,Q99729,Q13247,Q96PK6,Q01085,P31943,A0AV96,Q07955,P22626,Q14011,P62995,O14979,P52597,P09651,P26368,Q93062,Q8TBF4,Q01081,P51991,Q92804,Q01844,P38159,P98179,P23588,P35637 40 +RmlC-like jelly roll fold [IPR014710] 0.3636847022221735 0.2553535039546833 0.7984500790469369 1.0 0.8969015028208239 10 O00625 1 +HSP90, C-terminal domain [IPR037196] 0.4769924812030113 0.2356555207535914 0.8136999871484265 1.0 0.9068508274280443 4 P08238,P14625,P07900 3 +SH2 domain superfamily [IPR036860] 0.3565371458374208 0.2260197306096857 0.8211860745614539 1.0 0.909395584176118 10 P46108,Q7KZ85 2 +Nucleotide-binding alpha-beta plait domain superfamily [IPR012677] 0.3246018076118992 0.2259400845141451 0.8212480208814028 1.0 0.909395584176118 132 Q86V81,Q13242,P11940,P55795,Q14103,Q8IZ69,O60506,Q9BWF3,P98175,Q15056,Q8NDT2,O43347,Q8IY67,O43390,P31942,Q9UHX1,Q99729,Q13247,Q96PK6,Q01085,P31943,A0AV96,Q07955,P22626,Q14011,P62995,O14979,P52597,P09651,P26368,Q93062,Q8TBF4,Q01081,P51991,Q92804,Q01844,P38159,P98179,P23588,P35637 40 +Thiolase-like [IPR016039] 0.3624643138147059 0.2168473088282378 0.828327341918371 1.0 0.914937764766343 8 Q9BWD1 1 +Initiation factor 2B-like, C-terminal [IPR042529] 0.5246542393265 0.1958925342929564 0.8446942808335058 1.0 0.9265893432502166 3 Q9UI10,P49770 2 +UBA-like superfamily [IPR009060] 0.3027425564521493 0.1781752119147557 0.8585853762485671 1.0 0.9358674847583174 25 Q14157,O94888,Q5T6F2,P54725 4 +RNA polymerase, RBP11-like subunit [IPR036603] 0.4959422903516644 0.1701561649840887 0.8648873241983186 1.0 0.938615423966044 2 O15160 1 +DNA-directed RNA polymerase, insert domain superfamily [IPR036643] 0.4959422903516644 0.1701561649840887 0.8648873241983186 1.0 0.938615423966044 2 O15160 1 +NTF2-like domain superfamily [IPR032710] 0.3789411526339341 0.1685068289749809 0.8661845717442567 1.0 0.9389970302860774 6 O43615,Q9BRJ2 2 +Sterile alpha motif/pointed domain superfamily [IPR013761] 0.362432269717037 0.1623769907676272 0.8710089890788835 1.0 0.9431973022413644 7 Q13136,Q9Y3Z3,Q12800,Q5PRF9,Q9Y6Y8,Q9NZI7 6 +Papain-like cysteine peptidase superfamily [IPR038765] 0.3002276431898099 0.1490615245303247 0.8815050856187998 1.0 0.9511085945459667 23 P07858,Q96FW1,Q96K76 3 +Membrane associated eicosanoid/glutathione metabolism-like domain superfamily [IPR023352] 0.4806131650135326 0.1470356884584743 0.8831038511292864 1.0 0.9511085945459667 2 O14880 1 +START-like domain superfamily [IPR023393] 0.425667981223128 0.1328258654260936 0.8943310979516916 1.0 0.9611155630584738 4 Q9NQZ5 1 +GTP-binding protein, orthogonal bundle domain superfamily [IPR023179] 0.4658851818455 0.1276949108849167 0.8983904176474007 1.0 0.9619356416597024 2 Q9NVN8 1 +Mss4-like superfamily [IPR011057] 0.465284039675391 0.1269637888445949 0.89896905887231 1.0 0.9619356416597024 2 P13693 1 +R3H domain superfamily [IPR036867] 0.4759470835838696 0.1196130697196465 0.9047896659219774 1.0 0.9660818690973372 3 Q9H6S0,O95453 2 +SCP2 sterol-binding domain superfamily [IPR036527] 0.4530968129885582 0.0930095813536375 0.9258959494014936 1.0 0.9739562264361048 3 P51659,Q6YN16 2 +GINS, helical bundle-like domain superfamily [IPR036224] 0.377817853922444 0.0620312337297699 0.9505379589682944 1.0 0.9935623086900174 2 Q9BRT9 1 +Rhodanese-like domain superfamily [IPR036873] 0.4131088394467723 0.0592598985260992 0.952745101293373 1.0 0.994822172012954 3 P25325,Q99956 2 +Vacuolar protein sorting-associated protein 33, domain 3b [IPR043155] 0.311091073038763 0.0488647466058581 0.9610270834168432 1.0 0.9957262420910632 2 Q96AX1 1 +SNase-like, OB-fold superfamily [IPR035437] 0.3575939849624102 0.0481565814728712 0.96159145297926 1.0 0.9957262420910632 4 Q8NHU6,Q92667,Q9Y2W6 3 diff --git a/interpro_homologous_superfamily/selections.json b/interpro_homologous_superfamily/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..1170a10d2bafde43ff3af4033ce29a2c37c6ef3c --- /dev/null +++ b/interpro_homologous_superfamily/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 domain superfamily [IPR036815]", "2Fe-2S ferredoxin-like superfamily [IPR036010]", "30s ribosomal protein S13, C-terminal [IPR027437]", "4'-phosphopantetheinyl transferase domain superfamily [IPR037143]", "5'-3' exonuclease, C-terminal domain superfamily [IPR036279]", "5-formyltetrahydrofolate cyclo-ligase-like domain superfamily [IPR024185]", "50S ribosomal protein L10, insertion domain superfamily [IPR043164]", "50S ribosomal protein L30e-like [IPR029064]", "6-phosphogluconate dehydrogenase, domain 2 [IPR013328]", "6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily [IPR008927]", "AAR2, C-terminal domain superfamily [IPR038514]", "AAR2, N-terminal domain superfamily [IPR038516]", "ABC transporter type 1, transmembrane domain superfamily [IPR036640]", "ACP-like superfamily [IPR036736]", "ADF-H/Gelsolin-like domain superfamily [IPR029006]", "ADP-ribosylation/Crystallin J1 superfamily [IPR036705]", "AF1104-like superfamily [IPR036075]", "AH/BAR domain superfamily [IPR027267]", "AICAR transformylase, duplicated domain superfamily [IPR024051]", "AICAR transformylase, insert domain superfamily [IPR024050]", "AMP-binding enzyme, C-terminal domain superfamily [IPR045851]", "ANL, N-terminal domain [IPR042099]", "ANTH domain superfamily [IPR014712]", "AP-2 complex subunit mu, C-terminal superfamily [IPR036168]", "APC, N-terminal coiled-coil domain superfamily [IPR036149]", "ARFGAP/RecO-like zinc finger [IPR037278]", "ARID DNA-binding domain superfamily [IPR036431]", "ATP synthase subunit alpha, N-terminal domain-like superfamily [IPR023366]", "ATP synthase, F0 complex, subunit A superfamily [IPR035908]", "ATP synthase, F0 complex, subunit D superfamily, mitochondrial [IPR036228]", "ATP synthase, F1 complex, gamma subunit superfamily [IPR035968]", "ATP synthase, alpha subunit, C-terminal domain superfamily [IPR038376]", "ATP-NAD kinase, PpnK-type, C-terminal [IPR017437]", "ATP-grasp fold, subdomain 1 [IPR013815]", "ATP:guanido phosphotransferase, N-terminal domain superfamily [IPR036802]", "ATPase, F1/V1 complex, beta/alpha subunit, C-terminal [IPR024034]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily [IPR036121]", "ATPase, V1 complex, subunit H, C-terminal domain superfamily [IPR038497]", "ATPase, nucleotide binding domain [IPR043129]", "Acetylglutamate kinase-like superfamily [IPR036393]", "Aconitase, domain 2 [IPR015932]", "Aconitase, iron-sulfur domain [IPR036008]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 [IPR015931]", "Aconitase/3-isopropylmalate dehydratase, swivel [IPR015928]", "Actin-crosslinking [IPR008999]", "Actin-related protein 2/3 complex subunit 3 superfamily [IPR036753]", "Activator of Hsp90 ATPase, Aha1 [IPR036338]", "Acyl transferase domain superfamily [IPR001227]", "Acyl transferase/acyl hydrolase/lysophospholipase [IPR016035]", "Acyl-CoA N-acyltransferase [IPR016181]", "Acyl-CoA binding protein superfamily [IPR035984]", "Acyl-CoA dehydrogenase-like, C-terminal [IPR036250]", "Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily [IPR009100]", "Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily [IPR037069]", "Acyl-CoA thioesterase, double hotdog domain [IPR042171]", "Adaptor protein Cbl, N-terminal domain superfamily [IPR036537]", "Adenine nucleotide alpha hydrolase-like domains [IPR023382]", "Adenomatous polyposis coli protein [IPR026831]", "Adenosylhomocysteinase-like superfamily [IPR042172]", "Adenylate cyclase-associated CAP, C-terminal superfamily [IPR036223]", "Adenylate cyclase-associated CAP, N-terminal domain superfamily [IPR036222]", "Adenylate kinase, active site lid domain superfamily [IPR036193]", "Adenylosuccinate synthetase, domain 1 [IPR042109]", "Adenylosuccinate synthetase, domain 2 [IPR042110]", "Adenylosuccinate synthetase, domain 3 [IPR042111]", "Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily [IPR018162]", "Alba-like domain superfamily [IPR036882]", "Aldehyde dehydrogenase, C-terminal [IPR016163]", "Aldehyde dehydrogenase, N-terminal [IPR016162]", "Aldehyde/histidinol dehydrogenase [IPR016161]", "Aldolase-type TIM barrel [IPR013785]", "Alkaline-phosphatase-like, core domain superfamily [IPR017850]", "Allosteric substrate binding domain superfamily [IPR029009]", "Alpha-D-phosphohexomutase, C-terminal domain superfamily [IPR036900]", "Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III [IPR016055]", "Alpha-catenin/vinculin-like superfamily [IPR036723]", "Alpha-glycerophosphate oxidase, C-terminal domain superfamily [IPR038299]", "Alpha-helical ferredoxin [IPR009051]", "Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain superfamily [IPR036784]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily [IPR037151]", "Alpha/Beta hydrolase fold [IPR029058]", "Alpha/beta knot methyltransferases [IPR029028]", "Amidase signature (AS) superfamily [IPR036928]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 [IPR020751]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding superfamily [IPR008925]", "Aminoacyl-tRNA synthetase, class Ia, anticodon-binding [IPR009080]", "Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097]", "Aminotransferase-like, PLP-dependent enzymes [IPR036038]", "Ankyrin repeat-containing domain superfamily [IPR036770]", "Annexin superfamily [IPR037104]", "Anticodon-binding domain superfamily [IPR036621]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain superfamily [IPR036732]", "ApaG domain superfamily [IPR036767]", "ArfGAP domain superfamily [IPR038508]", "Arginyl tRNA synthetase N-terminal domain superfamily [IPR036695]", "Armadillo-like helical [IPR011989]", "Armadillo-type fold [IPR016024]", "Arp2/3 complex subunit 2/4 [IPR034666]", "Arrestin-like, C-terminal [IPR014752]", "Aspartate decarboxylase-like domain superfamily [IPR009010]", "Aspartate/ornithine carbamoyltransferase superfamily [IPR036901]", "Aspartic peptidase domain superfamily [IPR021109]", "Aspartyl/glutamyl-tRNA amidotransferase subunit B-like [IPR003789]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C-terminal, domain 2 [IPR023168]", "At2g17340, three-helix bundle domain [IPR035073]", "B30.2/SPRY domain superfamily [IPR043136]", "BAG domain superfamily [IPR036533]", "BEACH domain superfamily [IPR036372]", "BRCT domain superfamily [IPR036420]", "BRK domain superfamily [IPR037259]", "BRO1 domain superfamily [IPR038499]", "BSD domain superfamily [IPR035925]", "Band 7/SPFH domain superfamily [IPR036013]", "Barrier-to-autointegration factor, BAF superfamily [IPR036617]", "Bcl-2-like superfamily [IPR036834]", "Beta-Galactosidase/glucuronidase domain superfamily [IPR036156]", "Beta-catenin-interacting ICAT superfamily [IPR036911]", "Beta-grasp domain superfamily [IPR012675]", "Beta-hexosaminidase-like, domain 2 [IPR029018]", "Beta-lactamase/transpeptidase-like [IPR012338]", "BolA-like superfamily [IPR036065]", "Branched-chain-amino-acid aminotransferase-like, C-terminal [IPR043132]", "Branched-chain-amino-acid aminotransferase-like, N-terminal [IPR043131]", "Bromo adjacent homology (BAH) domain superfamily [IPR043151]", "Bromodomain-like superfamily [IPR036427]", "C-type lectin fold [IPR016187]", "C-type lectin-like/link domain superfamily [IPR016186]", "C2 domain superfamily [IPR035892]", "CAP Gly-rich domain superfamily [IPR036859]", "CCR4-NOT complex subunit 2/3/5, N-terminal domain superfamily [IPR038635]", "CCR4-NOT subunit 1, TTP binding domain superfamily [IPR038535]", "CDC48 domain 2-like superfamily [IPR029067]", "CDP-alcohol phosphatidyltransferase, transmembrane domain [IPR043130]", "CENP-B, dimerisation domain superfamily [IPR034882]", "CH domain superfamily [IPR036872]", "CRAL-TRIO lipid binding domain superfamily [IPR036865]", "CRAL/TRIO, N-terminal domain superfamily [IPR036273]", "CRIB domain superfamily [IPR036936]", "CSTF1, dimerization domain superfamily [IPR038184]", "Cadherin-like superfamily [IPR015919]", "Calcyclin-binding protein, N-terminal [IPR037201]", "Calpain large subunit, domain III superfamily [IPR036213]", "Calreticulin/calnexin, P domain superfamily [IPR009033]", "Calycin [IPR012674]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily [IPR036480]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily [IPR036897]", "Carbon-nitrogen hydrolase superfamily [IPR036526]", "Carboxypeptidase-like, regulatory domain superfamily [IPR008969]", "Carnitine o-acyltransferase, N-terminal [IPR042572]", "Casein kinase II subunit beta-like [IPR035991]", "Casein kinase II, regulatory subunit, N-terminal [IPR016149]", "Caspase-like domain superfamily [IPR029030]", "Catenin binding domain superfamily [IPR027397]", "Cathepsin C, exclusion domain superfamily [IPR036496]", "Cation efflux transmembrane domain superfamily [IPR027469]", "Cdc37, Hsp90-binding domain superfamily [IPR038189]", "Cell division control protein 73, C-terminal domain superfamily [IPR038103]", "Chaperone J-domain superfamily [IPR036869]", "Chitinase insertion domain superfamily [IPR029070]", "Chloramphenicol acetyltransferase-like domain superfamily [IPR023213]", "Chloride channel, core [IPR014743]", "Choline/Carnitine o-acyltransferase, domain 2 [IPR042231]", "Chromo-like domain superfamily [IPR016197]", "Citrate synthase superfamily [IPR036969]", "Citrate synthase-like, large alpha subdomain [IPR016142]", "Citrate synthase-like, small alpha subdomain [IPR016143]", "Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm [IPR010978]", "Class I glutamine amidotransferase-like [IPR029062]", "Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) [IPR045864]", "Class II aldolase/adducin N-terminal domain superfamily [IPR036409]", "Clathrin adaptor, appendage, Ig-like subdomain superfamily [IPR013041]", "Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain [IPR013037]", "Clathrin heavy chain, N-terminal [IPR016025]", "ClpP/crotonase-like domain superfamily [IPR029045]", "Coatomer, gamma subunit, appendage domain superfamily [IPR037067]", "Coatomer/calthrin adaptor appendage, C-terminal subdomain [IPR009028]", "Cobalamin (vitamin B12)-dependent enzyme, catalytic [IPR016176]", "Cobalamin adenosyltransferase-like superfamily [IPR036451]", "Cobalamin-binding domain superfamily [IPR036724]", "Concanavalin A-like lectin/glucanase domain superfamily [IPR013320]", "Creatinase/Aminopeptidase P/Spt16, N-terminal [IPR029149]", "Creatinase/aminopeptidase-like [IPR036005]", "Cullin homology domain superfamily [IPR036317]", "Cullin repeat-like-containing domain superfamily [IPR016159]", "Cupredoxin [IPR008972]", "Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal [IPR016098]", "Cyclic nucleotide-binding-like [IPR018490]", "Cyclic phosphodiesterase [IPR009097]", "Cyclin-like superfamily [IPR036915]", "Cyclophilin-like domain superfamily [IPR029000]", "Cytidine deaminase-like [IPR016193]", "Cytochrome C oxidase subunit II, transmembrane domain superfamily [IPR036257]", "Cytochrome P450 superfamily [IPR036396]", "Cytochrome b-c1 complex subunit 7 superfamily [IPR036544]", "Cytochrome b-c1 complex subunit 8 superfamily [IPR036642]", "Cytochrome b-c1 complex subunit 9 superfamily [IPR036656]", "Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400]", "Cytochrome bc1 complex subunit Rieske, transmembrane domain superfamily [IPR037008]", "Cytochrome c oxidase assembly protein CtaG/Cox11, domain superfamily [IPR023471]", "Cytochrome c oxidase subunit IV superfamily [IPR036639]", "Cytochrome c oxidase subunit VIIc superfamily [IPR036636]", "Cytochrome c oxidase, subunit VIIa superfamily [IPR036539]", "Cytochrome c oxidase, subunit Va/VI superfamily [IPR036545]", "Cytochrome c oxidase, subunit Vb superfamily [IPR036972]", "Cytochrome c-like domain superfamily [IPR036909]", "Cytochrome c1, transmembrane anchor, C-terminal [IPR021157]", "Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily [IPR011048]", "DCN1-like, PONY binding domain [IPR042460]", "DENN domain, C-terminal lobe [IPR043153]", "DHBP synthase RibB-like alpha/beta domain superfamily [IPR017945]", "DHS-like NAD/FAD-binding domain superfamily [IPR029035]", "DIX domain superfamily [IPR038207]", "DNA breaking-rejoining enzyme, catalytic core [IPR011010]", "DNA fragmentation factor 45kDa, C-terminal [IPR027296]", "DNA ligase, ATP-dependent, N-terminal domain superfamily [IPR036599]", "DNA mismatch repair protein MutS, N-terminal [IPR016151]", "DNA mismatch repair protein MutS, core domain superfamily [IPR036187]", "DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal [IPR008921]", "DNA polymerase alpha, subunit B, N-terminal domain superfamily [IPR043034]", "DNA polymerase alpha, zinc finger domain superfamily [IPR038256]", "DNA polymerase family B, thumb domain [IPR042087]", "DNA polymerase, palm domain superfamily [IPR023211]", "DNA repair protein XRCC4-like, C-terminal [IPR014751]", "DNA topoisomerase I, DNA binding, N-terminal domain 1 [IPR013034]", "DNA topoisomerase I, DNA binding, N-terminal domain 2 [IPR013030]", "DNA topoisomerase I, DNA binding, eukaryotic-type, N-terminal domain superfamily [IPR036202]", "DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type [IPR014711]", "DNA topoisomerase I, catalytic core, alpha/beta subdomain [IPR014727]", "DNA topoisomerase, type IIA, alpha-helical domain superfamily [IPR013757]", "DNA topoisomerase, type IIA, domain A, alpha-beta [IPR013758]", "DNA topoisomerase, type IIA, subunit B, C-terminal [IPR013759]", "DNA topoisomerase, type IIA-like domain superfamily [IPR013760]", "DNA-binding domain superfamily [IPR016177]", "DNA-directed RNA polymerase, N-terminal domain superfamily [IPR037159]", "DNA-directed RNA polymerase, insert domain superfamily [IPR036643]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily [IPR037033]", "DNA/RNA non-specific endonuclease superfamily [IPR044929]", "DNA/RNA polymerase superfamily [IPR043502]", "DNA/RNA-binding protein KIN17, WH-like domain superfamily [IPR038254]", "DUSP-like superfamily [IPR035927]", "Daxx, N-terminal domain superfamily [IPR038298]", "Dbl homology (DH) domain superfamily [IPR035899]", "Death-like domain superfamily [IPR011029]", "Dedicator of cytokinesis, C-terminal, lobe A [IPR043161]", "Dedicator of cytokinesis, C-terminal, lobe C [IPR043162]", "Deoxyhypusine synthase superfamily [IPR036982]", "DhaL domain superfamily [IPR036117]", "Diaphanous, GTPase-binding domain superfamily [IPR044933]", "Dicer dimerisation domain superfamily [IPR038248]", "Dihydrofolate reductase-like domain superfamily [IPR024072]", "Dihydropteroate synthase-like [IPR011005]", "Dimeric alpha-beta barrel [IPR011008]", "Diphthamide synthesis DPH1/DPH2, domain 1 [IPR042263]", "Diphthamide synthesis DPH1/DPH2, domain 3 [IPR042265]", "Disintegrin domain superfamily [IPR036436]", "Dynein heavy chain AAA lid domain superfamily [IPR042219]", "Dynein heavy chain, AAA1 domain, small subdomain [IPR043157]", "Dynein heavy chain, C-terminal domain, barrel region [IPR043160]", "Dynein heavy chain, domain 2, N-terminal [IPR042222]", "Dynein heavy chain, linker, subdomain 3 [IPR042228]", "Dynein light chain superfamily [IPR037177]", "E3 ubiquitin-protein ligase ELL-like [IPR042065]", "E3-binding domain superfamily [IPR036625]", "EB1, C-terminal domain superfamily [IPR036133]", "EF-G domain III/V-like [IPR035647]", "EF-hand domain pair [IPR011992]", "ENTH/VHS [IPR008942]", "ERO1-like superfamily [IPR037192]", "ERV/ALR sulfhydryl oxidase domain superfamily [IPR036774]", "ESCRT assembly domain [IPR037202]", "ESCRT-II complex, Vps25 subunit, N-terminal winged helix [IPR014041]", "EXOC6/PINT-1/Sec15/Tip20, C-terminal, domain 2 [IPR042044]", "Elongation factor EF1B gamma, C-terminal domain superfamily [IPR036433]", "Elongation factor Ts, dimerisation domain superfamily [IPR036402]", "Endonuclease/exonuclease/phosphatase superfamily [IPR036691]", "Endoplasmic reticulum resident protein 29, C-terminal domain superfamily [IPR036356]", "Enhancer of mRNA-decapping protein 4, conserved C-terminal domain [IPR044938]", "Enhancer of rudimentary superfamily [IPR035912]", "Enolase-like, C-terminal domain superfamily [IPR036849]", "Enolase-like, N-terminal [IPR029017]", "Enoyl-CoA hydratase, C-terminal [IPR014748]", "Eukaryotic translation initiation factor 3-like domain superfamily [IPR023194]", "Exocyst complex component EXOC3/Sec6, C-terminal domain [IPR042532]", "Exocyst complex component EXOC6/Sec15, C-terminal, domain 1 [IPR042045]", "Exocyst component Exo84, C-terminal, subdomain 1 [IPR042561]", "Exocyst component Exo84, C-terminal, subdomain 2 [IPR042560]", "Exoribonuclease, PH domain 2 superfamily [IPR036345]", "F-actin capping protein, alpha subunit, domain 1 [IPR042489]", "F-actin-capping protein subunit alpha/beta [IPR037282]", "F-actin-capping protein subunit alpha/beta, domain 2 [IPR042276]", "F-actin-capping protein subunit beta, N-terminal domain [IPR043175]", "F-box-like domain superfamily [IPR036047]", "F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily [IPR026015]", "FAD-binding, type PCMH, subdomain 1 [IPR016167]", "FAD-binding, type PCMH, subdomain 2 [IPR016169]", "FAD-binding, type PCMH-like superfamily [IPR036318]", "FAD-linked oxidase-like, C-terminal [IPR016164]", "FAD/NAD(P)-binding domain superfamily [IPR036188]", "FAD/NAD-linked reductase, dimerisation domain superfamily [IPR016156]", "FERM superfamily, second domain [IPR035963]", "FERM/acyl-CoA-binding protein superfamily [IPR014352]", "FF domain superfamily [IPR036517]", "FIP-RBD, C-terminal domain superfamily [IPR037245]", "FKBP12-rapamycin binding domain superfamily [IPR036738]", "FMN-binding split barrel [IPR012349]", "FTO, C-terminal domain superfamily [IPR038413]", "Fe-S cluster assembly domain superfamily [IPR034904]", "Ferredoxin-NADP reductase (FNR), nucleotide-binding domain [IPR039261]", "Ferritin-like superfamily [IPR009078]", "Fibronectin type II domain superfamily [IPR036943]", "Fibronectin type III superfamily [IPR036116]", "Flavoprotein-like superfamily [IPR029039]", "Formin, FH2 domain superfamily [IPR042201]", "Formyl transferase, N-terminal domain superfamily [IPR036477]", "Formyl transferase-like, C-terminal domain superfamily [IPR011034]", "Fumarase/histidase, N-terminal [IPR024083]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily [IPR037099]", "Fumarylacetoacetase, N-terminal domain superfamily [IPR036462]", "Fumarylacetoacetase-like, C-terminal domain superfamily [IPR036663]", "G protein alpha subunit, helical insertion [IPR011025]", "G-protein gamma-like domain superfamily [IPR036284]", "GAD-like domain superfamily [IPR004115]", "GAR domain superfamily [IPR036534]", "GAT domain superfamily [IPR038425]", "GBBH-like, N-terminal domain superfamily [IPR038492]", "GHMP kinase, C-terminal domain superfamily [IPR036554]", "GINS complex, subunit Psf3 superfamily [IPR038437]", "GINS, helical bundle-like domain superfamily [IPR036224]", "GM2-AP, lipid-recognition domain superfamily [IPR036846]", "GMP phosphodiesterase, delta subunit superfamily [IPR037036]", "GOLD domain superfamily [IPR036598]", "GSKIP domain superfamily [IPR023231]", "GTF2I-like repeat superfamily [IPR036647]", "GTP-binding protein TrmE/Aminomethyltransferase GcvT, domain 1 [IPR027266]", "GTP-binding protein, orthogonal bundle domain superfamily [IPR023179]", "GTP1/OBG domain superfamily [IPR036726]", "GYF-like domain superfamily [IPR035445]", "Galactose mutarotase-like domain superfamily [IPR011013]", "Galactose oxidase/kelch, beta-propeller [IPR011043]", "Galactose-binding-like domain superfamily [IPR008979]", "Gamma-glutamyl cyclotransferase-like superfamily [IPR036568]", "Gamma-glutamyltranspeptidase, large subunit, C-terminal domain [IPR043138]", "Gamma-glutamyltranspeptidase, small subunit [IPR043137]", "Gamma-tubulin complex component, C-terminal domain superfamily [IPR042241]", "Gelsolin-like domain superfamily [IPR036180]", "Globular protein, non-globular alpha/beta subunit [IPR011070]", "Glu-tRNAGln amidotransferase superfamily, subunit C [IPR036113]", "Glutamine synthetase/guanido kinase, catalytic domain [IPR014746]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 1 [IPR042558]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 2 [IPR042559]", "Glutathione S-transferase, C-terminal domain superfamily [IPR036282]", "Glutathione synthase, C-terminal, eukaryotic [IPR014709]", "Glutathione synthase, N-terminal, eukaryotic [IPR014049]", "Glutathione synthase, alpha-helical [IPR014042]", "Glutathione synthase, substrate-binding domain superfamily [IPR037013]", "Glycine cleavage T-protein/YgfZ, C-terminal [IPR029043]", "Glycoside hydrolase 38, N-terminal domain superfamily [IPR027291]", "Glycoside hydrolase families 57/38, central domain superfamily [IPR028995]", "Glycoside hydrolase family 38, central domain superfamily [IPR037094]", "Glycoside hydrolase superfamily [IPR017853]", "Glycoside hydrolase-type carbohydrate-binding [IPR014718]", "Glycoside hydrolase/deacetylase, beta/alpha-barrel [IPR011330]", "Glycosyl hydrolase family 63, N-terminal domain superfamily [IPR038518]", "Glycosyl hydrolase, all-beta [IPR013780]", "Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [IPR029068]", "Golgi phosphoprotein 3-like domain superfamily [IPR038261]", "GroEL-like apical domain superfamily [IPR027409]", "GroEL-like equatorial domain superfamily [IPR027413]", "GroES chaperonin superfamily [IPR037124]", "GroES-like superfamily [IPR011032]", "Growth arrest and DNA damage-inducible proteins-interacting protein 1 domain superfamily [IPR043035]", "Growth factor receptor cysteine-rich domain superfamily [IPR009030]", "GrpE nucleotide exchange factor, coiled-coil [IPR013805]", "GrpE nucleotide exchange factor, head [IPR009012]", "Guanylate-binding protein, C-terminal domain superfamily [IPR036543]", "H/ACA RNP complex subunit Gar1/Naf1, Cbf5-binding domain [IPR038664]", "HAD superfamily [IPR023214]", "HAD-like superfamily [IPR036412]", "HBS1-like protein, N-terminal domain superfamily [IPR037189]", "HECT, E3 ligase catalytic domain [IPR035983]", "HIT-like superfamily [IPR036265]", "HIV integrase-binding domain superfamily [IPR036218]", "HR1 repeat superfamily [IPR036274]", "HRDC domain superfamily [IPR044876]", "HRDC-like superfamily [IPR010997]", "HSP20-like chaperone [IPR008978]", "HSP40/DnaJ peptide-binding [IPR008971]", "HSP90, C-terminal domain [IPR037196]", "Haem oxygenase-like, multi-helical [IPR016084]", "Heat shock protein 70kD, C-terminal domain superfamily [IPR029048]", "Heat shock protein 70kD, peptide-binding domain superfamily [IPR029047]", "Heat shock protein DnaJ, cysteine-rich domain superfamily [IPR036410]", "Heavy metal-associated domain superfamily [IPR036163]", "Helix hairpin bin domain superfamily [IPR029012]", "Helix-loop-helix DNA-binding domain superfamily [IPR036638]", "Hemimethylated DNA-binding domain superfamily [IPR036623]", "High mobility group box domain superfamily [IPR036910]", "His-Me finger superfamily [IPR044925]", "Histidine kinase/HSP90-like ATPase superfamily [IPR036890]", "Histidine phosphatase superfamily [IPR029033]", "Histone acetyl transferase 1, N-terminal domain superfamily [IPR037113]", "Histone acetyltransferase HAT1, C-terminal [IPR013523]", "Histone deacetylase domain superfamily [IPR037138]", "Histone-fold [IPR009072]", "Homeobox-like domain superfamily [IPR009057]", "Homocysteine-binding domain superfamily [IPR036589]", "HotDog domain superfamily [IPR029069]", "I/LWEQ domain superfamily [IPR035964]", "ISWI, HAND domain superfamily [IPR036306]", "Immunoglobulin E-set [IPR014756]", "Immunoglobulin-like domain superfamily [IPR036179]", "Immunoglobulin-like fold [IPR013783]", "Importin-alpha, importin-beta-binding domain superfamily [IPR036975]", "Initiation factor 2B-like, C-terminal [IPR042529]", "Inorganic polyphosphate/ATP-NAD kinase, N-terminal [IPR017438]", "Inorganic pyrophosphatase superfamily [IPR036649]", "Inosine triphosphate pyrophosphatase-like [IPR029001]", "Integrase-like, N-terminal [IPR017856]", "Integrin beta tail domain superfamily [IPR036349]", "Integrin domain superfamily [IPR032695]", "Interferon regulatory factor 2-binding protein 1/2, C3HC4-type RING finger superfamily [IPR044882]", "Invasin/intimin cell-adhesion fragments [IPR008964]", "Isochorismatase-like superfamily [IPR036380]", "Isopenicillin N synthase-like superfamily [IPR027443]", "Isoprenoid synthase domain superfamily [IPR008949]", "K Homology domain, type 1 superfamily [IPR036612]", "K homology domain superfamily, prokaryotic type [IPR009019]", "K homology domain-like, alpha/beta [IPR015946]", "KA1 domain/Ssp2, C-terminal [IPR028375]", "Kelch-type beta propeller [IPR015915]", "Kinesin motor domain superfamily [IPR036961]", "Kinesin-like protein Kif23, Arf6-interacting domain superfamily [IPR038105]", "Kringle-like fold [IPR013806]", "Ku, C-terminal domain superfamily [IPR036494]", "Ku70, bridge and pillars domain superfamily [IPR027388]", "L-Aspartase-like [IPR008948]", "L21-like superfamily [IPR036164]", "L27 domain superfamily [IPR036892]", "L28p-like [IPR034704]", "LAP1C-like, C-terminal domain superfamily [IPR038599]", "LDL receptor-like superfamily [IPR036055]", "LEM/LEM-like domain superfamily [IPR011015]", "LIS1, N-terminal [IPR037190]", "LOTUS-like domain [IPR041966]", "LSM domain superfamily [IPR010920]", "Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal [IPR015955]", "Lambda repressor-like, DNA-binding domain superfamily [IPR010982]", "Lamin tail domain superfamily [IPR036415]", "Leucine-rich repeat domain superfamily [IPR032675]", "LexA/Signal peptidase-like superfamily [IPR036286]", "Longin-like domain superfamily [IPR011012]", "MAGE homology domain, winged helix WH1 motif [IPR041898]", "MAGE homology domain, winged helix WH2 motif [IPR041899]", "MAN1, winged-helix domain [IPR041885]", "MFS transporter superfamily [IPR036259]", "MHC class I-like antigen recognition-like superfamily [IPR037055]", "MHC classes I/II-like antigen recognition protein [IPR011162]", "MIT domain superfamily [IPR036181]", "MOB kinase activator superfamily [IPR036703]", "MRG, C-terminal domain superfamily [IPR038217]", "MRP-L47 superfamily, mitochondrial [IPR038340]", "MTERF superfamily, mitochondrial/chloroplastic [IPR038538]", "MTH938-like superfamily [IPR036748]", "Macro domain-like [IPR043472]", "Malic enzyme, N-terminal domain superfamily [IPR037062]", "Malonyl-CoA ACP transacylase, ACP-binding [IPR016036]", "Manganese/iron superoxide dismutase, C-terminal domain superfamily [IPR036314]", "Manganese/iron superoxide dismutase, N-terminal domain superfamily [IPR036324]", "Mannose-6-phosphate receptor binding domain superfamily [IPR009011]", "Mediator complex, subunit Med7/Med21-like [IPR037212]", "Membrane associated eicosanoid/glutathione metabolism-like domain superfamily [IPR023352]", "Metal-dependent hydrolase [IPR032466]", "Metal-dependent hydrolase, composite domain superfamily [IPR011059]", "Metallo-dependent phosphatase-like [IPR029052]", "Metalloenzyme, LuxS/M16 peptidase-like [IPR011249]", "Metallopeptidase, catalytic domain superfamily [IPR024079]", "Methionine synthase domain [IPR036594]", "Methionyl-tRNA synthetase, Zn-domain [IPR029038]", "Methylglyoxal synthase-like domain superfamily [IPR036914]", "Methylpurine-DNA glycosylase superfamily [IPR036995]", "Methylthiotransferase, N-terminal domain superfamily [IPR038135]", "Mib/herc2 domain superfamily [IPR037252]", "Mir domain superfamily [IPR036300]", "MitoNEET, CDGSH iron-sulfur domain [IPR042216]", "Mitochondrial carrier domain superfamily [IPR023395]", "Mitochondrial cytochrome c oxidase subunit VIc/VIIs superfamily [IPR037169]", "Mitochondrial glycoprotein superfamily [IPR036561]", "Mitochondrial outer membrane translocase complex, Tom20 domain superfamily [IPR023392]", "Mitochondrial ribosomal protein L55 superfamily [IPR044884]", "MoaB/Mog-like domain superfamily [IPR036425]", "MoeA, C-terminal, domain IV superfamily [IPR036688]", "MoeA, N-terminal and linker domain superfamily [IPR036135]", "Moesin tail domain superfamily [IPR008954]", "Mog1/PsbP, alpha/beta/alpha sandwich [IPR016123]", "Mre11, capping domain [IPR038487]", "Mss4-like superfamily [IPR011057]", "Mss4/translationally controlled tumour-associated TCTP [IPR011323]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain superfamily [IPR042179]", "MutS, connector domain superfamily [IPR036678]", "Myosin S1 fragment, N-terminal [IPR008989]", "NAC A/B domain superfamily [IPR038187]", "NAD kinase/diacylglycerol kinase-like domain superfamily [IPR016064]", "NAD(P)-binding domain superfamily [IPR036291]", "NADH-quinone oxidoreductase subunit E, N-terminal [IPR041921]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily [IPR037225]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily [IPR037207]", "NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily [IPR037232]", "NADP-dependent oxidoreductase domain superfamily [IPR036812]", "NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamily [IPR023173]", "NAP-like superfamily [IPR037231]", "NET domain superfamily [IPR038336]", "NO signalling/Golgi transport ligand-binding domain superfamily [IPR024096]", "NOB1 zinc finger-like superfamily [IPR036283]", "NSFL1 cofactor p47, SEP domain superfamily [IPR036241]", "NTF2-like domain superfamily [IPR032710]", "NUDIX hydrolase-like domain superfamily [IPR015797]", "NVL2, N-terminal domain superfamily [IPR038100]", "NagB/RpiA transferase-like [IPR037171]", "Ndc80 domain superfamily [IPR038273]", "Neurolysin/Thimet oligopeptidase, N-terminal [IPR024080]", "Neurolysin/Thimet oligopeptidase, domain 2 [IPR024077]", "Nibrin, second BRCT domain superfamily [IPR043014]", "Nicotinate phosphoribosyltransferase-like, C-terminal [IPR036068]", "Nitrogen regulatory PII-like, alpha/beta [IPR011322]", "Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal [IPR015867]", "Nitrous oxide reductase, N-terminal [IPR011045]", "Nop domain superfamily [IPR036070]", "Nop, C-terminal domain [IPR042239]", "Nucleic acid-binding, OB-fold [IPR012340]", "Nucleophile aminohydrolases, N-terminal [IPR029055]", "Nucleoplasmin core domain superfamily [IPR036824]", "Nucleoporin, Nup155-like, C-terminal, subdomain 1 [IPR042533]", "Nucleoporin, Nup155-like, C-terminal, subdomain 2 [IPR042537]", "Nucleoporin, Nup155-like, C-terminal, subdomain 3 [IPR042538]", "Nucleoside diphosphate kinase-like domain superfamily [IPR036850]", "Nucleoside phosphorylase superfamily [IPR035994]", "Nucleotide-binding alpha-beta plait domain superfamily [IPR012677]", "Nucleotide-diphospho-sugar transferases [IPR029044]", "Nucleotidyltransferase superfamily [IPR043519]", "Nucleotidyltransferase, class I-like, C-terminal [IPR011068]", "Nuf2, N-terminal domain superfamily [IPR038275]", "NusG, N-terminal domain superfamily [IPR036735]", "Oxygen-dependent coproporphyrinogen III oxidase superfamily [IPR036406]", "Oxysterol-binding protein superfamily [IPR037239]", "P-loop containing nucleoside triphosphate hydrolase [IPR027417]", "P-type ATPase, A domain superfamily [IPR008250]", "P-type ATPase, cytoplasmic domain N [IPR023299]", "P-type ATPase, transmembrane domain superfamily [IPR023298]", "P-type trefoil domain superfamily [IPR044913]", "PABC (PABP) domain [IPR036053]", "PADR1 domain superfamily [IPR038650]", "PAZ domain superfamily [IPR036085]", "PBDC1-like domain superfamily [IPR023139]", "PCGF Ub-like fold discriminator superfamily [IPR038227]", "PD-(D/E)XK endonuclease-like domain superfamily [IPR011604]", "PDCD5-like superfamily [IPR036883]", "PDZ superfamily [IPR036034]", "PEBP-like superfamily [IPR036610]", "PFU domain superfamily [IPR038122]", "PH-like domain superfamily [IPR011993]", "PHR domain superfamily [IPR038648]", "PIN-like domain superfamily [IPR029060]", "PITH domain superfamily [IPR037047]", "PKD domain superfamily [IPR035986]", "PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily [IPR017946]", "PLP-binding barrel [IPR029066]", "PNPase/RNase PH domain superfamily [IPR027408]", "POLO box domain superfamily [IPR036947]", "PPM-type phosphatase domain superfamily [IPR036457]", "PRP4-like superfamily [IPR036285]", "PTPA superfamily [IPR037218]", "PUA domain superfamily [IPR036974]", "PUA-like superfamily [IPR015947]", "PWI domain superfamily [IPR036483]", "PX domain superfamily [IPR036871]", "Paired amphipathic helix superfamily [IPR036600]", "PapD-like superfamily [IPR008962]", "Papain-like cysteine peptidase superfamily [IPR038765]", "Pectin lyase fold [IPR012334]", "Pectin lyase fold/virulence factor [IPR011050]", "Pelota/DOM34, N-terminal domain [IPR038069]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase superfamily [IPR036959]", "Peptidase C65, otubain, subdomain 2 [IPR042467]", "Peptidase C65, otubain, subdomain 1 [IPR042468]", "Peptidase M1, LTA-4 hydrolase/aminopeptidase, C-terminal domain superfamily [IPR038502]", "Peptidase M13, domain 2 [IPR042089]", "Peptidase M4/M1, CTD superfamily [IPR027268]", "Peptidase M41-like [IPR037219]", "Peptidase M60, enhancin-like domain 3 [IPR042279]", "Peptidase S1, PA clan [IPR009003]", "Peptidase S59, nucleoporin superfamily [IPR036903]", "Peptidase S8/S53 domain superfamily [IPR036852]", "Peptidyl-tRNA hydrolase II domain superfamily [IPR023476]", "Pex19, C-terminal domain superfamily [IPR038322]", "Phenylalanyl-tRNA synthetase-like, B3/B4 [IPR020825]", "Phosphatidic acid phosphatase type 2/haloperoxidase superfamily [IPR036938]", "Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily [IPR036940]", "Phosphatidylinositol-4-phosphate 5-kinase, N-terminal [IPR027484]", "Phosphoenolpyruvate carboxykinase, C-terminal [IPR013035]", "Phosphoenolpyruvate carboxykinase, N-terminal [IPR008210]", "Phosphofructokinase superfamily [IPR035966]", "Phosphoglucose isomerase, C-terminal [IPR023096]", "Phosphoglycerate kinase superfamily [IPR036043]", "Phosphoglycerate kinase, N-terminal [IPR015824]", "Phosphoglycolate phosphatase-like, domain 2 [IPR023198]", "Phosphoinositide 3-kinase, accessory (PIK) domain superfamily [IPR042236]", "Phospholipase B-like, domain 1 [IPR043040]", "Phospholipase B-like, domain 2 [IPR043041]", "Phospholipase B-like, domain 3 [IPR043042]", "Phospholipase C-beta, C-terminal domain superfamily [IPR042531]", "Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily [IPR036604]", "Phosphoribosylglycinamide synthetase, C-domain superfamily [IPR037123]", "Phosphoribosyltransferase-like [IPR029057]", "Phosphorylated adapter RNA export protein, RNA-binding domain superfamily [IPR038092]", "Phosphotyrosine protein phosphatase I superfamily [IPR036196]", "Phosphotyrosyl phosphatase activator, C-terminal lid domain [IPR043170]", "Plakin repeat superfamily [IPR035915]", "Plus3-like superfamily [IPR036128]", "Poly(ADP-ribose) polymerase, regulatory domain superfamily [IPR036616]", "Polyketide synthase, dehydratase domain superfamily [IPR042104]", "Polymerase/histidinol phosphatase-like [IPR016195]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain superfamily [IPR036456]", "Porin domain superfamily [IPR023614]", "Porphobilinogen deaminase, C-terminal domain superfamily [IPR036803]", "Pre-ATP-grasp domain superfamily [IPR016185]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding domain superfamily [IPR042516]", "Pre-mRNA-splicing factor Isy1 superfamily [IPR037200]", "Prefoldin [IPR009053]", "Profilin superfamily [IPR036140]", "Prolyl-tRNA synthetase, class II [IPR017449]", "Proteasomal ubiquitin receptor Rpn13/ADRM1, Pru domain superfamily [IPR038633]", "Proteasome activator PA28, C-terminal domain superfamily [IPR036997]", "Proteasome activator PA28, N-terminal domain superfamily [IPR036996]", "Proteasome activator superfamily [IPR036252]", "Proteasome assembly chaperone 2 superfamily [IPR038389]", "Protein arginine methyltransferase NDUFAF7 superfamily [IPR038375]", "Protein kinase-like domain superfamily [IPR011009]", "Protein-tyrosine phosphatase-like [IPR029021]", "Prp8 RNase domain IV, fingers region [IPR043173]", "Prp8 RNase domain IV, palm region [IPR043172]", "Pseudouridine synthase I, TruA, C-terminal [IPR020095]", "Pseudouridine synthase TruA/RsuA/RluB/E/F, N-terminal [IPR020094]", "Pseudouridine synthase, TruD, catalytic domain [IPR042214]", "Pseudouridine synthase, catalytic domain superfamily [IPR020103]", "Pterin 4 alpha carbinolamine dehydratase superfamily [IPR036428]", "PurM-like, C-terminal domain superfamily [IPR036676]", "PurM-like, N-terminal domain superfamily [IPR036921]", "Putative DNA-binding domain superfamily [IPR009061]", "Putative deacetylase LmbE-like domain superfamily [IPR024078]", "Pyridoxal phosphate-dependent transferase [IPR015424]", "Pyridoxal phosphate-dependent transferase, major domain [IPR015421]", "Pyridoxal phosphate-dependent transferase, small domain [IPR015422]", "Pyruvate kinase, C-terminal domain superfamily [IPR036918]", "Pyruvate kinase, insert domain superfamily [IPR015806]", "Pyruvate kinase-like domain superfamily [IPR040442]", "Pyruvate kinase-like, insert domain superfamily [IPR011037]", "Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily [IPR015813]", "Queuine tRNA-ribosyltransferase-like [IPR036511]", "Quinoprotein alcohol dehydrogenase-like superfamily [IPR011047]", "Quinoprotein amine dehydrogenase, beta chain-like [IPR011044]", "R3H domain superfamily [IPR036867]", "RAP domain superfamily [IPR036744]", "RGS domain superfamily [IPR036305]", "RNA 3'-terminal phosphate cyclase domain superfamily [IPR037136]", "RNA 3'-terminal phosphate cyclase, insert domain superfamily [IPR036553]", "RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta [IPR013792]", "RNA polymerase Rpb1, clamp domain superfamily [IPR044893]", "RNA polymerase Rpb1, domain 3 superfamily [IPR042102]", "RNA polymerase Rpb1, domain 7 superfamily [IPR038593]", "RNA polymerase Rpb1, funnel domain superfamily [IPR038120]", "RNA polymerase Rpb2, OB-fold [IPR014724]", "RNA polymerase Rpb2, domain 2 superfamily [IPR037034]", "RNA polymerase Rpb5, N-terminal domain superfamily [IPR036710]", "RNA polymerase Rpb7-like, N-terminal domain superfamily [IPR036898]", "RNA polymerase subunit RPB10 [IPR023580]", "RNA polymerase, RBP11-like subunit [IPR036603]", "RNA-binding S4 domain superfamily [IPR036986]", "RNA-binding domain superfamily [IPR035979]", "RPB5-like RNA polymerase subunit superfamily [IPR035913]", "RPN13, DEUBAD domain superfamily [IPR038108]", "RRF superfamily [IPR036191]", "RUN domain superfamily [IPR037213]", "Rab geranylgeranyltransferase, alpha subunit, insert-domain superfamily [IPR036254]", "Rab-GTPase-TBC domain superfamily [IPR035969]", "Radical SAM, alpha/beta horseshoe [IPR023404]", "Ran-GTPase activating protein 1, C-terminal domain superfamily [IPR036720]", "Rap/Ran-GAP superfamily [IPR035974]", "Ras guanine nucleotide exchange factor domain superfamily [IPR023578]", "Ras guanine-nucleotide exchange factor, catalytic domain superfamily [IPR036964]", "Receptor L-domain superfamily [IPR036941]", "Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II [IPR009091]", "Regulatory factor, effector binding domain superfamily [IPR011256]", "Rel homology domain (RHD), DNA-binding domain superfamily [IPR037059]", "Restriction endonuclease type II-like [IPR011335]", "Rho GDP-dissociation inhibitor domain superfamily [IPR024792]", "Rho GTPase activation protein [IPR008936]", "Rhodanese-like domain superfamily [IPR036873]", "Rhomboid-like superfamily [IPR035952]", "Riboflavin synthase-like beta-barrel [IPR017938]", "Ribokinase-like [IPR029056]", "Ribonuclease H superfamily [IPR036397]", "Ribonuclease H-like superfamily [IPR012337]", "Ribonuclease H1, N-terminal domain superfamily [IPR037056]", "Ribonuclease HII, helix-loop-helix cap domain superfamily [IPR023160]", "Ribonuclease III, endonuclease domain superfamily [IPR036389]", "Ribonuclease T2-like superfamily [IPR036430]", "Ribonuclease Z/Hydroxyacylglutathione hydrolase-like [IPR036866]", "Ribonucleotide reductase R1 subunit, N-terminal [IPR008926]", "Ribonucleotide reductase-like [IPR012348]", "Ribosomal L15/L27a, N-terminal [IPR027386]", "Ribosomal L18e/L15P superfamily [IPR036227]", "Ribosomal RNA-processing protein 8, N-terminal domain [IPR042036]", "Ribosomal protein L1, 3-layer alpha/beta-sandwich [IPR016095]", "Ribosomal protein L1-like [IPR023674]", "Ribosomal protein L10-like domain superfamily [IPR043141]", "Ribosomal protein L10e/L16 superfamily [IPR036920]", "Ribosomal protein L11, C-terminal domain superfamily [IPR036769]", "Ribosomal protein L11/L12, N-terminal domain superfamily [IPR036796]", "Ribosomal protein L13 superfamily [IPR036899]", "Ribosomal protein L14 superfamily [IPR036853]", "Ribosomal protein L15e core domain superfamily [IPR024794]", "Ribosomal protein L17 superfamily [IPR036373]", "Ribosomal protein L19 superfamily [IPR038657]", "Ribosomal protein L19/L19e superfamily [IPR035970]", "Ribosomal protein L19/L19e, domain 1 [IPR015972]", "Ribosomal protein L2, domain 2 [IPR014722]", "Ribosomal protein L2, domain 3 [IPR014726]", "Ribosomal protein L21 superfamily [IPR036948]", "Ribosomal protein L22/L17 superfamily [IPR036394]", "Ribosomal protein L22e superfamily [IPR038526]", "Ribosomal protein L23/L15e core domain superfamily [IPR012678]", "Ribosomal protein L24e/L24 superfamily [IPR038630]", "Ribosomal protein L25/Gln-tRNA synthetase, N-terminal [IPR020056]", "Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily [IPR011035]", "Ribosomal protein L27e superfamily [IPR038655]", "Ribosomal protein L28/L24 superfamily [IPR037147]", "Ribosomal protein L29/L35 superfamily [IPR036049]", "Ribosomal protein L3, domain 3, archaeal type superfamily [IPR044892]", "Ribosomal protein L30, ferredoxin-like fold domain superfamily [IPR036919]", "Ribosomal protein L31e domain superfamily [IPR023621]", "Ribosomal protein L32e superfamily [IPR036351]", "Ribosomal protein L35A superfamily [IPR038661]", "Ribosomal protein L36e domain superfamily [IPR038097]", "Ribosomal protein L37ae/L37e [IPR011331]", "Ribosomal protein L38e superfamily [IPR038464]", "Ribosomal protein L4 domain superfamily [IPR023574]", "Ribosomal protein L5 domain superfamily [IPR022803]", "Ribosomal protein L6, alpha-beta domain superfamily [IPR036789]", "Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like [IPR014719]", "Ribosomal protein L7/L12, oligomerisation domain superfamily [IPR036235]", "Ribosomal protein L9, N-terminal domain superfamily [IPR036935]", "Ribosomal protein L9/RNase H1, N-terminal [IPR009027]", "Ribosomal protein P1/P2, N-terminal domain [IPR038716]", "Ribosomal protein S10 domain superfamily [IPR036838]", "Ribosomal protein S11 superfamily [IPR036967]", "Ribosomal protein S13-like, H2TH [IPR010979]", "Ribosomal protein S16 domain superfamily [IPR023803]", "Ribosomal protein S17e-like superfamily [IPR036401]", "Ribosomal protein S18 superfamily [IPR036870]", "Ribosomal protein S19/S15, superfamily [IPR023575]", "Ribosomal protein S2, flavodoxin-like domain superfamily [IPR023591]", "Ribosomal protein S21e superfamily [IPR038579]", "Ribosomal protein S26e superfamily [IPR038551]", "Ribosomal protein S3, C-terminal domain superfamily [IPR036419]", "Ribosomal protein S4e, central domain superfamily [IPR038237]", "Ribosomal protein S5 domain 2-type fold [IPR020568]", "Ribosomal protein S5 domain 2-type fold, subgroup [IPR014721]", "Ribosomal protein S7 domain superfamily [IPR036823]", "Ribosomal protein S8 superfamily [IPR035987]", "Ribosomal protein S8e subdomain, eukaryotes [IPR042563]", "Ribosome maturation protein SBDS, N-terminal domain superfamily [IPR036786]", "Ribosome maturation protein Sdo1/SBDS, central domain superfamily [IPR037188]", "Ribosome-associated complex head domain superfamily [IPR042569]", "Ribulose-phosphate binding barrel [IPR011060]", "Ricin B-like lectins [IPR035992]", "RmlC-like cupin domain superfamily [IPR011051]", "RmlC-like jelly roll fold [IPR014710]", "Rossmann-like alpha/beta/alpha sandwich fold [IPR014729]", "Rpb4/RPC9 superfamily [IPR038324]", "Rudiment single hybrid motif [IPR011054]", "RutC-like superfamily [IPR035959]", "RuvA domain 2-like [IPR010994]", "RuvBL1/2, DNA/RNA binding domain [IPR042487]", "S-adenosyl-L-methionine-dependent methyltransferase [IPR029063]", "S-adenosylmethionine synthetase superfamily [IPR022636]", "S15/NS1, RNA-binding [IPR009068]", "SAP domain superfamily [IPR036361]", "SAS-6, N-terminal domain superfamily [IPR038558]", "SCAN domain superfamily [IPR038269]", "SCP2 sterol-binding domain superfamily [IPR036527]", "SGNH hydrolase superfamily [IPR036514]", "SH2 domain superfamily [IPR036860]", "SH3-like domain superfamily [IPR036028]", "SKA1 microtubule binding domain [IPR042031]", "SKP1-like, dimerisation domain superfamily [IPR036296]", "SKP1/BTB/POZ domain superfamily [IPR011333]", "SLED domain superfamily [IPR038348]", "SMAD/FHA domain superfamily [IPR008984]", "SMCs flexible hinge superfamily [IPR036277]", "SNARE [IPR010989]", "SNF2-like, N-terminal domain superfamily [IPR038718]", "SNase-like, OB-fold superfamily [IPR035437]", "SOCS box-like domain superfamily [IPR036036]", "SOS response associated peptidase-like [IPR036590]", "SPOC-like, C-terminal domain superfamily [IPR016194]", "SRA-YDG superfamily [IPR036987]", "SRCR-like domain superfamily [IPR036772]", "SRP/SRP receptor, N-terminal [IPR036225]", "SRP68, N-terminal domain superfamily [IPR038253]", "SSRP1 domain superfamily [IPR038167]", "START-like domain superfamily [IPR023393]", "STAT transcription factor, DNA-binding, N-terminal [IPR012345]", "STAT transcription factor, N-terminal domain superfamily [IPR036535]", "STAT transcription factor, coiled coil [IPR015988]", "STAT1, C-terminal domain superfamily [IPR038295]", "SUI1 domain superfamily [IPR036877]", "SWAP/Surp superfamily [IPR035967]", "Saposin-like [IPR011001]", "Scaffold protein Nfu/NifU, N-terminal domain superfamily [IPR036498]", "Scavenger mRNA decapping enzyme, N-terminal [IPR011145]", "Schlafen, AlbA_2 domain superfamily [IPR038461]", "ScpA-like, C-terminal [IPR023093]", "Sec1-like superfamily [IPR036045]", "Sec1-like, domain 1 [IPR043154]", "Sec1-like, domain 2 [IPR027482]", "Sec1-like, domain 3a [IPR043127]", "Sec23/Sec24 helical domain superfamily [IPR036175]", "Sec7 domain superfamily [IPR035999]", "Sec7, C-terminal domain superfamily [IPR023394]", "SecY domain superfamily [IPR023201]", "Serine carboxypeptidase S28, SKS domain [IPR042269]", "Serine-tRNA synthetase, type1, N-terminal domain superfamily [IPR042103]", "Serpin superfamily [IPR036186]", "Serpin superfamily, domain 1 [IPR042178]", "Serpin superfamily, domain 2 [IPR042185]", "Seven-hairpin glycosidases [IPR036026]", "Signal recognition particle SRP54, N-terminal domain superfamily [IPR042101]", "Signal recognition particle, SRP54 subunit, M-domain superfamily [IPR036891]", "Signal recognition particle, SRP9/SRP14 subunit [IPR009018]", "Signal recognition particle, subunit SRP19-like superfamily [IPR036521]", "Sin3 associated polypeptide p18 superfamily [IPR042534]", "Single hybrid motif [IPR011053]", "Sirtuin, catalytic core small domain superfamily [IPR026591]", "Six-bladed beta-propeller, TolB-like [IPR011042]", "Six-hairpin glycosidase superfamily [IPR008928]", "Six-hairpin glycosidase-like superfamily [IPR012341]", "Smac/DIABLO-like superfamily [IPR009062]", "Smaug, PHAT domain superfamily [IPR037093]", "Sodium/potassium-transporting ATPase subunit beta superfamily [IPR038702]", "Sodium:dicarboxylate symporter superfamily [IPR036458]", "Sodium:neurotransmitter symporter superfamily [IPR037272]", "Soluble quinoprotein glucose/sorbosone dehydrogenase [IPR011041]", "Spermidine synthase, tetramerisation domain superfamily [IPR037163]", "Spt6, Death-like domain [IPR042066]", "Stathmin superfamily [IPR036002]", "Sterile alpha motif/pointed domain superfamily [IPR013761]", "Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily [IPR027477]", "Succinyl-CoA synthetase-like [IPR016102]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain superfamily [IPR042568]", "TAP42/TAP46-like superfamily [IPR038511]", "TBCC, N-terminal domain superfamily [IPR038397]", "TBP domain superfamily [IPR012295]", "TCP-1-like chaperonin intermediate domain superfamily [IPR027410]", "TEL2, C-terminal domain superfamily [IPR038528]", "TFIIIC, subcomplex tauA subunit Sfc1, triple barrel domain superfamily [IPR042536]", "TFIIS/LEDGF domain superfamily [IPR035441]", "TGS-like [IPR012676]", "TGS-like domain superfamily [IPR023192]", "TRAF-like [IPR008974]", "TRF2-interacting telomeric protein/Rap1, C-terminal domain superfamily [IPR038104]", "TROVE domain superfamily [IPR037214]", "Talin, central domain superfamily [IPR036476]", "Taurine dioxygenase TauD-like superfamily [IPR042098]", "Tautomerase/MIF superfamily [IPR014347]", "Telomere repeat-binding factor, dimerisation domain superfamily [IPR036507]", "Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid [IPR008930]", "Tetrapyrrole methylase superfamily [IPR035996]", "Tetrapyrrole methylase, subdomain 1 [IPR014777]", "Tetrapyrrole methylase, subdomain 2 [IPR014776]", "Tetraspanin, EC2 domain superfamily [IPR008952]", "Tetratricopeptide-like helical domain superfamily [IPR011990]", "Tex-like domain superfamily [IPR023323]", "Tex-like protein, HTH domain superfamily [IPR023319]", "Thiamin diphosphate-binding fold [IPR029061]", "Thiolase-like [IPR016039]", "Thioredoxin-like superfamily [IPR036249]", "Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily [IPR018163]", "Thymidylate synthase/dCMP hydroxymethylase superfamily [IPR036926]", "Tim10-like domain superfamily [IPR035427]", "Tma16 superfamily [IPR038356]", "Transcription Factor IIF, Rap30/Rap74, interaction [IPR011039]", "Transcription elongation factor S-II, central domain superfamily [IPR036575]", "Transcription termination and cleavage factor, C-terminal domain superfamily [IPR038192]", "Transcriptional regulator TACO1-like, domain 3 [IPR026564]", "Transferrin receptor-like, dimerisation domain superfamily [IPR036757]", "Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II [IPR009014]", "Translation Initiation factor eIF- 4e-like [IPR023398]", "Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal [IPR009001]", "Translation elongation factor EF1B/ribosomal protein S6 [IPR014717]", "Translation elongation factor eEF-1beta-like superfamily [IPR036219]", "Translation initiation factor 2, alpha subunit, C-terminal [IPR024055]", "Translation initiation factor 2, alpha subunit, middle domain superfamily [IPR024054]", "Translation initiation factor 3, subunit 12, N-terminal, eukaryotic [IPR016020]", "Translation initiation factor IF-2, domain 3 superfamily [IPR036925]", "Translation initiation factor IF2/IF5, N-terminal [IPR016189]", "Translation initiation factor IF2/IF5, zinc-binding [IPR016190]", "Translation initiation factor eIF-2B subunit alpha, N-terminal [IPR042528]", "Translation protein SH3-like domain superfamily [IPR008991]", "Translation protein, beta-barrel domain superfamily [IPR009000]", "Translin superfamily [IPR036081]", "Translin, C-terminal [IPR016069]", "Translin, N-terminal [IPR016068]", "Trimeric LpxA-like superfamily [IPR011004]", "Triosephosphate isomerase superfamily [IPR035990]", "TspO/MBR-related superfamily [IPR038330]", "Tubulin binding cofactor A superfamily [IPR036126]", "Tubulin, C-terminal [IPR023123]", "Tubulin/FtsZ, C-terminal [IPR008280]", "Tubulin/FtsZ, GTPase domain superfamily [IPR036525]", "Tubulin/FtsZ-like, C-terminal domain [IPR037103]", "UBA-like superfamily [IPR009060]", "UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily [IPR036220]", "UROD/MetE-like superfamily [IPR038071]", "Ubiquitin activating enzyme, alpha domain superfamily [IPR023318]", "Ubiquitin-activating enzyme E1, C-terminal domain superfamily [IPR038252]", "Ubiquitin-activating enzyme E1, FCCH domain superfamily [IPR042302]", "Ubiquitin-activating enzyme E1, SCCH domain [IPR042063]", "Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1 [IPR042449]", "Ubiquitin-activating enzyme [IPR035985]", "Ubiquitin-conjugating enzyme/RWD-like [IPR016135]", "Ubiquitin-like domain superfamily [IPR029071]", "Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain superfamily [IPR042556]", "Ufd1-like, Nn domain [IPR042299]", "Ureohydrolase domain superfamily [IPR023696]", "V-type ATPase subunit E, C-terminal domain superfamily [IPR038495]", "VASP tetramerisation domain superfamily [IPR038023]", "VKOR domain superfamily [IPR038354]", "VPS9 domain superfamily [IPR037191]", "Vacuolar ATP synthase subunit C superfamily [IPR036132]", "Vacuolar protein sorting-associated protein 33, domain 3b [IPR043155]", "Vacuolar protein sorting-associated protein 35, C-terminal [IPR042491]", "Vacuolar protein sorting-associated protein IST1-like [IPR042277]", "Valyl-tRNA synthetase, tRNA-binding arm superfamily [IPR037118]", "Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain [IPR009008]", "Vanillyl-alcohol oxidase, C-terminal subdomain 2 [IPR016171]", "Vesicle transport v-SNARE, N-terminal domain superfamily [IPR038407]", "Vitamin B12-dependent methionine synthase, activation domain superfamily [IPR037010]", "Vps53, C-terminal domain superfamily [IPR038260]", "Vta1/Callose synthase, N-terminal domain superfamily [IPR023175]", "WD40-repeat-containing domain superfamily [IPR036322]", "WD40/YVTN repeat-like-containing domain superfamily [IPR015943]", "WGR domain superfamily [IPR036930]", "WIBG, N-terminal domain superfamily [IPR036348]", "WW domain superfamily [IPR036020]", "WWE domain superfamily [IPR037197]", "Winged helix DNA-binding domain superfamily [IPR036390]", "Winged helix-like DNA-binding domain superfamily [IPR036388]", "Wiscott-Aldrich syndrome protein, C-terminal [IPR011026]", "XPC-binding domain superfamily [IPR036353]", "YEATS superfamily [IPR038704]", "YebC-like [IPR029072]", "YjeF N-terminal domain superfamily [IPR036652]", "YqgF/RNase H-like domain superfamily [IPR037027]", "ZPR1, A/B domain [IPR042451]", "ZPR1, zinc finger domain [IPR042452]", "Zinc finger C2H2 superfamily [IPR036236]", "Zinc finger, C2H2C-type superfamily [IPR036060]", "Zinc finger, CCCH-type superfamily [IPR036855]", "Zinc finger, CCHC-type superfamily [IPR036875]", "Zinc finger, FYVE/PHD-type [IPR011011]", "Zinc finger, NHR/GATA-type [IPR013088]", "Zinc finger, PARP-type superfamily [IPR036957]", "Zinc finger, RING/FYVE/PHD-type [IPR013083]", "Zinc finger, RanBP2-type superfamily [IPR036443]", "Zinc finger, Sec23/Sec24-type superfamily [IPR036174]", "Zinc finger, ZZ-type superfamily [IPR043145]", "Zinc-binding ribosomal protein [IPR011332]", "dUTPase-like superfamily [IPR036157]", "eRF1, domain 1 [IPR024049]", "eRF1, domain 2 superfamily [IPR042226]", "mRNA decapping protein 2, Box A domain superfamily [IPR036189]", "p53-like tetramerisation domain superfamily [IPR036674]", "p53-like transcription factor, DNA-binding [IPR008967]", "p53/RUNT-type transcription factor, DNA-binding domain superfamily [IPR012346]", "rRNA adenine dimethylase-like, C-terminal [IPR023165]", "ssDNA-binding transcriptional regulator [IPR009044]", "tRNA (guanine-N1-)-methyltransferase, N-terminal [IPR029026]", "tRNA methyltransferase TRM10-type domain superfamily [IPR038459]", "tRNA methyltransferase, Trm1, C-terminal [IPR042296]", "tRNA modification GTPase MnmE domain 2 [IPR027368]", "tRNA-splicing ligase RtcB-like superfamily [IPR036025]", "tRNAHis guanylyltransferase Thg1 superfamily [IPR038469]", "von Willebrand factor A-like domain superfamily [IPR036465]"], "available_proteins": ["AAAS", "AACS", "AAK1", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "ABCB1", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD11", "ABHD12", "ABHD14B", "ABHD6", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ADA", "ADAM17", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP13", "AKR1A1", "AKR1B1", "AKT1", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG13", "ALG5", "ALKBH1", "ALKBH5", "ALYREF", "ANAPC1", "ANAPC2", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APC", "APEH", "APEX1", "API5", "APMAP", "APOBEC3C", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP3", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGAP35", "ARHGAP5", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6", "ARL8B", "ARMC1", "ARMC10", "ARMC6", "ARMC9", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARVCF", "ASB6", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATE1", "ATF7IP", "ATG4B", "ATIC", "ATL2", "ATL3", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5H", "ATP5O", "ATP6", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP6V1H", "ATRX", "ATXN10", "ATXN2", "B4GALT1", "BABAM1", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAX", "BAZ1A", "BAZ1B", "BCAT2", "BCL2L12", "BCL2L13", "BCOR", "BCS1L", "BDH2", "BIRC6", "BLM", "BLMH", "BLVRA", "BLVRB", "BMS1", "BOLA2*", "BOP1", "BPTF", "BRAP", "BRAT1", "BRCA1", "BRD2", "BRD4", "BROX", "BSG", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BZW1", "BZW2", "C1QBP", "C2CD5", "CAB39", "CACUL1", "CACYBP", "CAD", "CADM1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAP2", "CAPN1", "CAPN2", "CAPNS1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CASK", "CASP2", "CASP3", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC88A", "CCNA2", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD47", "CDC23", "CDC25C", "CDC27", "CDC37", "CDC42", "CDC42BPB", "CDC5L", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK4", "CDK5", "CDK5RAP1", "CDK6", "CDKAL1", "CDKN2A", "CDX2", "CEBPZ", "CECR2", "CELF1", "CENPB", "CENPE", "CENPV", "CEP170", "CERS2", "CETN2", "CFL1", "CFL2", "CHAC2", "CHAF1B", "CHAMP1", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHKA", "CHORDC1", "CHP1", "CHRAC1", "CHTF18", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CIZ1", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLTC", "CLUH", "CMAS", "CMBL", "CMPK1", "CMSS1", "CNN2", "CNN3", "CNOT1", "CNOT3", "CNOT7", "CNOT9", "CNP", "COA7", "COASY", "COLEC12", "COLGALT1", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPZ1", "COQ8A", "CORO1B", "CORO1C", "COTL1", "COX11", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTDSPL2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWC22", "CWF19L1", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYP20A1", "CYP51A1", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF7", "DCAF8", "DCAKD", "DCP1A", "DCP1B", "DCP2", "DCPS", "DCTD", "DCTN1", "DCUN1D5", "DCXR", "DDB1", "DDI2", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DENND4C", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHFR", "DHODH", "DHPS", "DHRS1", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DIS3L2", "DKC1", "DLAT", "DLD", "DLST", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPM1", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTL", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EDC3", "EDC4", "EDF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFL1", "EFTUD2", "EGFR", "EHBP1", "EHD1", "EHD4", "EHMT2", "EIF2A", "EIF2AK2", "EIF2AK4", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3B", "EIF3E", "EIF3G", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELL", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP4", "EMC1", "EMC2", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L5", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC6B", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXTL3", "EZR", "F11R", "FABP5", "FAF1", "FAF2", "FAH", "FAHD1", "FAR1", "FARSA", "FARSB", "FASN", "FBL", "FBXO22", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FH", "FHOD1", "FIS1", "FKBP10", "FKBP14", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNBP4", "FNDC3A", "FNTB", "FOXRED1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCDH", "GCLM", "GCN1", "GDAP1", "GDAP2", "GDI1", "GDI2", "GDPD1", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGCT", "GGCX", "GGH", "GGT7", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNE", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GNPNAT1", "GNS", "GOLPH3", "GOLPH3L", "GOPC", "GORASP2", "GOT1", "GOT2", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPS1", "GPSM1", "GPT2", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUSB", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAGH", "HARS2", "HAT1", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HELLS", "HERC4", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HMBS", "HMCES", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGXB4", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOXD13", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA6", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDE", "IDI1", "IFIT5", "IFNGR1", "IFT27", "IFT88", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPDH1", "IMPDH2", "INF2", "INPP4A", "INTS1", "INTS11", "INTS12", "INTS14", "INTS7", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRS4", "ISG20L2", "ISOC1", "ISOC2", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITSN2", "IVD", "IWS1", "JUP", "KARS", "KAT7", "KCTD12", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1468", "KIF11", "KIF14", "KIF15", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRR1", "L2HGDH", "LACTB", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LCMT1", "LDHA", "LDHB", "LDLR", "LDLRAP1", "LEMD2", "LEMD3", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LPCAT1", "LRBA", "LRCH2", "LRP1", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRWD1", "LSM14A", "LSM14B", "LSM2", "LSM6", "LSS", "LTA4H", "LTN1", "LYAR", "LYPLA1", "LYPLAL1", "LZIC", "M6PR", "MACF1", "MAGED1", "MAGED2", "MAGT1", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP2K1", "MAP2K3", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARK1", "MARK2", "MARS", "MAT2A", "MAT2B", "MATR3", "MAVS", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MED16", "MED21", "MEPCE", "METAP1", "METAP2", "METTL1", "METTL13", "METTL16", "METTL3", "MFN1", "MFN2", "MFSD10", "MFSD5", "MGAT1", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MICALL1", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MKLN1", "MKRN2", "MMAB", "MMS19", "MOB4", "MOGS", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPG", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MRC2", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL22", "MRPL23", "MRPL28", "MRPL3", "MRPL39", "MRPL4", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL55", "MRPL9", "MRPS10", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS25", "MRPS27", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTERF3", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR2", "MTOR", "MTPAP", "MTR", "MTSS1L", "MTX1", "MTX2", "MTX3", "MUT", "MVK", "MYBBP1A", "MYCBP2", "MYEF2", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA16", "NAA40", "NAA50", "NACC1", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG", "NCAPG2", "NCBP1", "NCDN", "NCL", "NCOA5", "NCOR1", "NDC80", "NDRG3", "NDUFA10", "NDUFA9", "NDUFAF3", "NDUFAF7", "NDUFS1", "NDUFS3", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEK9", "NELFE", "NENF", "NFATC2IP", "NFKB1", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL8", "NOL9", "NOM1", "NONO", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NRDE2", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSUN2", "NSUN5", "NSUN6", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUB1", "NUBPL", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP98", "NVL", "NXF1", "NXN", "OAT", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAIP1", "PAK1", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PAXIP1", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCYOX1", "PDCD11", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXDC1", "PDXK", "PDZD8", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN1", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGGT1B", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF2", "PHF3", "PHF6", "PHF8", "PHGDH", "PHIP", "PI4KA", "PI4KB", "PICALM", "PIGG", "PIGL", "PIK3C2A", "PIK3C3", "PIK3R4", "PIN1", "PIP4K2B", "PIR", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCB3", "PLCG1", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPO", "PNPT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "PON2", "POR", "PPA1", "PPA2", "PPAT", "PPFIA1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRKAA1", "PRKAA2", "PRKACA", "PRKAR1A", "PRKAR2A", "PRKAR2B", "PRKCD", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF39", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG2", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN23", "PTPN9", "PTPRF", "PTRH2", "PTRHD1", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PWP1", "PWP2", "PYCR1", "PYCR2", "PYM1", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABEPK", "RABGAP1", "RABGGTA", "RABGGTB", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RANGRF", "RAP1GDS1", "RAPGEF2", "RAPGEF6", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM47", "RBM5", "RBM8A", "RBMX", "RBPMS", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "RECQL5", "REPS1", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIPK1", "RMDN1", "RNASEH2A", "RNASET2", "RNF14", "RNF20", "RNF219", "RNF220", "RNF40", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS8", "RPS9", "RPSA", "RPTOR", "RPUSD2", "RRAS2", "RREB1", "RRM1", "RRM2", "RRM2B", "RRP12", "RRP8", "RRP9", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCA", "RTCB", "RTF1", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SAAL1", "SACS", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAP18", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART3", "SASS6", "SBDS", "SBNO1", "SCAF11", "SCAF4", "SCCPDH", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCYL2", "SDAD1", "SDCBP", "SDF2L1", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEH1L", "SEL1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SF1", "SF3A1", "SF3A2", "SF3B1", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGPL1", "SGTA", "SH3BGRL", "SH3BGRL2", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SIN3A", "SIRT1", "SKA1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A5", "SLC25A6", "SLC27A4", "SLC30A7", "SLC3A2", "SLC4A1AP", "SLC6A15", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMAP2", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC6", "SMCHD1", "SMS", "SMU1", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPECC1", "SPECC1L", "SPEN", "SPHK2", "SPNS1", "SPOUT1", "SPR", "SPRYD4", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRBD1", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "STAG1", "STAG2", "STAM", "STARD7", "STAT1", "STAT3", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STUB1", "STX12", "STX4", "STX6", "STX7", "STXBP2", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SYAP1", "SYMPK", "SYNCRIP", "SYNE1", "SYNE2", "SYNJ2BP", "TAB1", "TACO1", "TAF15", "TAGLN2", "TALDO1", "TANGO6", "TAP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D17", "TBC1D2B", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCA", "TBCB", "TBCC", "TBCD", "TBCE", "TBK1", "TBL1XR1", "TBL2", "TBL3", "TCAF1", "TCEA1", "TCERG1", "TCP1", "TDRD7", "TDRKH", "TECR", "TELO2", "TERF2", "TERF2IP", "TEX10", "TEX264", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFRC", "TGS1", "THG1L", "THOC1", "THOC3", "THOC6", "THOP1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TIMM9", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLN1", "TMA16", "TMED2", "TMED5", "TMED7", "TMEM63A", "TMLHE", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOM1", "TOMM20", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52L2", "TPI1", "TPM4", "TPMT", "TPP1", "TPP2", "TPT1", "TRA2A", "TRA2B", "TRAP1", "TRAPPC4", "TRAPPC5", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIO", "TRIP12", "TRIP13", "TRMT1", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TRMU", "TROVE2", "TRUB1", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN10", "TSPAN3", "TSPAN6", "TSPO", "TSPYL1", "TTC1", "TTC19", "TTC26", "TTC27", "TTC28", "TTC37", "TTC38", "TTC4", "TTF2", "TTI1", "TTK", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXN2", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAP2", "UBAP2L", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE2T", "UBE3A", "UBE3C", "UBE4A", "UBL5", "UBLCP1", "UBP1", "UBQLN1", "UBQLN2", "UBQLN4", "UBR1", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFD1", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119B", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "UROD", "USO1", "USP10", "USP11", "USP14", "USP15", "USP24", "USP28", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "UXT", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIRMA", "VKORC1L1", "VPS25", "VPS26A", "VPS26B", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37C", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK2", "VTA1", "VTI1B", "WAPL", "WARS", "WARS2", "WASL", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR36", "WDR4", "WDR41", "WDR43", "WDR45B", "WDR46", "WDR48", "WDR5", "WDR6", "WDR61", "WDR70", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WNK1", "WNK2", "WRAP53", "WRAP73", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "YAP1", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YEATS4", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H15", "ZC3H18", "ZC3HAV1", "ZCCHC11", "ZCCHC3", "ZCRB1", "ZFR", "ZFYVE16", "ZMYND8", "ZNF24", "ZNF281", "ZNF512B", "ZNF622", "ZNF638", "ZPR1", "ZRANB2"], "leading_proteins": ["ABHD10", "ABHD12", "ACAT2", "ADAM17", "AIFM1", "AKAP1", "ALKBH5", "ALYREF", "ANAPC5", "ANAPC7", "ANKLE2", "ARFIP2", "ARMT1", "ATP13A1", "ATP13A2", "B4GALT1", "BAG4", "BAG5", "BAIAP2", "BSG", "CALM3", "CALU", "CD2BP2", "CDKAL1", "CIRBP", "CLUH", "CMBL", "CPVL", "CRK", "CRNKL1", "CRTAP", "CTPS1", "CTPS2", "CTSA", "CTSB", "CYB5B", "CYP51A1", "DNAJA1", "DNAJA2", "DUSP9", "DYNLL2", "ECE1", "EFCAB14", "EIF2B2", "EIF2B4", "EIF2B5", "EIF3L", "EIF4B", "EIF4H", "EPHX1", "ERAL1", "ERAP1", "ERLIN1", "ERLIN2", "ETFDH", "EWSR1", "EXTL3", "FIS1", "FKBP10", "FKBP14", "FKBP4", "FKBP5", "FKBP7", "FLOT1", "FMR1", "FNTB", "FOXRED1", "FTO", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "GALNT2", "GBA", "GBE1", "GFPT1", "GGH", "GGT7", "GINS4", "GLA", "GMPPA", "GMPPB", "GNL3L", "GOLPH3", "GRB2", "GSTA4", "GSTO1", "GTPBP3", "GYG1", "HLA-A", "HLA-C", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPR", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "IBA57", "IGF2R", "KDM1A", "KDM1B", "KHDRBS3", "KHSRP", "KIAA0391", "KLC1", "KLC2", "LMAN1", "LNPEP", "LSS", "M6PR", "MAN1A2", "MAPRE2", "MGAT1", "MGEA5", "MGST3", "MINDY3", "MIPEP", "MPP2", "MPP6", "MPST", "MRC2", "MRPL43", "MRPL45", "MSI1", "MTCH2", "NAGLU", "NAP1L4", "NENF", "NISCH", "NLN", "NPEPPS", "NPTN", "NT5C3A", "NT5C3B", "NUCB1", "NUCB2", "NXN", "OTUB1", "P3H1", "P3H4", "P4HA1", "P4HA2", "PABPC1", "PARN", "PCYOX1", "PDCD6", "PDCL3", "PFDN1", "PFDN2", "PGGT1B", "PGRMC2", "PHB", "PHB2", "PI4KA", "PIR", "PLA2G15", "PLOD3", "POLR1C", "POLR2B", "PPFIA1", "PPT1", "PPT2", "PRCP", "PRDX3", "PRMT9", "PSMA1", "PSMA6", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMD11", "PTPRF", "PUF60", "RAD23A", "RAVER1", "RBM10", "RBM14", "RBM15B", "RBM3", "RBM4", "RBM47", "RBMX", "RBPMS", "RCN2", "REPS1", "RINT1", "RRM2B", "SAMD4B", "SAMHD1", "SCO1", "SCPEP1", "SEC23IP", "SEL1L", "SET", "SGPL1", "SHMT1", "SLC18B1", "SLC25A11", "SLC25A15", "SLC25A20", "SLC25A26", "SLC25A32", "SLC25A33", "SLC25A4", "SNX12", "SNX27", "SPTLC2", "SQLE", "SRSF1", "SRSF6", "SRSF9", "STAM", "STARD7", "STOM", "STOML2", "STX12", "STX6", "STX7", "SUPT6H", "SYNCRIP", "TAF15", "TAP1", "TBC1D10A", "TBC1D15", "TBC1D4", "TBC1D8B", "TBC1D9B", "TDRD7", "TDRKH", "TFCP2", "TIAL1", "TIMM44", "TIMM8A", "TIMM8B", "TMTC3", "TMX4", "TPT1", "TRA2B", "TRIM21", "TRMT2A", "TSN", "TSPAN6", "TTC19", "TTC26", "TTC27", "TTC37", "TTC38", "TXNDC12", "TXNL1", "U2AF1", "U2AF2", "UBAP2", "UBAP2L", "UBP1", "UBR5", "UBXN7", "UGCG", "UNC119B", "USP47", "UXT", "VDAC1", "VPS33A", "WFS1", "YTHDC2", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZCRB1"]} \ No newline at end of file diff --git a/interpro_ptm/advanced/idx2term.json b/interpro_ptm/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_ptm/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_ptm/basic/idx2term.json b/interpro_ptm/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_ptm/basic/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_ptm/consensus.joblib b/interpro_ptm/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..030eb9c6f0df9c3b9c5ebdb72cdfa02ebf198f07 --- /dev/null +++ b/interpro_ptm/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:cf94a08c21ead7b51ff30a8b65459895efce02329f58014aeee0770b97cf7cd5 +size 73914 diff --git a/interpro_ptm/df_merge.tsv b/interpro_ptm/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_ptm/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_ptm/metrics.json b/interpro_ptm/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..0448d42640b363086b683066a7ac2cc9db25e405 --- /dev/null +++ b/interpro_ptm/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3329, + "annotations_size": 4, + "title": "Average number of proteins per term", + "value": 2.5 +} \ No newline at end of file diff --git a/interpro_ptm/paths.json b/interpro_ptm/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..64ef4c965dc6bbdcebb8e4d091c1f21d76a82282 --- /dev/null +++ b/interpro_ptm/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_ptm/fragment/C342/C342_val_log2fc"} \ No newline at end of file diff --git a/interpro_ptm/result.tsv b/interpro_ptm/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..3b6be6d21d2e76b1befafcaa977d9093cfb87a65 --- /dev/null +++ b/interpro_ptm/result.tsv @@ -0,0 +1,2 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +P-type ATPase, phosphorylation site [IPR018303] 0.7539943771241531 1.5218790146467065 0.1280393982865071 0.4219206583619768 0.2560787965730142 5 Q9NQ11,Q9HD20 2 diff --git a/interpro_ptm/selections.json b/interpro_ptm/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..1544949dd3dbc6e92204b453bb7ee1ab6cc0f43c --- /dev/null +++ b/interpro_ptm/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["EGF-type aspartate/asparagine hydroxylation site [IPR000152]", "P-type ATPase, phosphorylation site [IPR018303]", "Phosphopantetheine attachment site [IPR006162]", "Translation elongation factor, IF5A, hypusine site [IPR019769]"], "available_proteins": ["ATP13A1", "ATP13A2", "ATP1A1", "ATP2A2", "ATP2B1", "EIF5A", "FASN", "LDLR", "LRP1", "SLIT2"], "leading_proteins": ["ATP13A1", "ATP13A2"]} \ No newline at end of file diff --git a/interpro_repeat/advanced/idx2term.json b/interpro_repeat/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..6dce773863970e13dd9ed6c0019ab4c4e97de280 --- /dev/null +++ b/interpro_repeat/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial substrate/solute carrier [IPR018108]"} \ No newline at end of file diff --git a/interpro_repeat/advanced/plot_0.png b/interpro_repeat/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..db77a43256e4fefdfb6e48f9ffb5d8222038831e --- /dev/null +++ b/interpro_repeat/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:09fedad2c8f26ca34b2adf4969b3bdc7e52e1915ead307f79baf0b18b8fa6828 +size 190099 diff --git a/interpro_repeat/basic/idx2term.json b/interpro_repeat/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..89347332fd727e794f5dc31a862dff01327a7f4e --- /dev/null +++ b/interpro_repeat/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial substrate/solute carrier [IPR018108]", "1": "Tetratricopeptide repeat [IPR019734]"} \ No newline at end of file diff --git a/interpro_repeat/basic/plot_0.png b/interpro_repeat/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..f36bf57bface0df3f3205d438a05a0282168e427 --- /dev/null +++ b/interpro_repeat/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c02dde885240594c63e1a81d23f66f5cba3d7ace2d866cbe1a941f5bcf223239 +size 143368 diff --git a/interpro_repeat/basic/plot_1.png b/interpro_repeat/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..0486ebfd3432b5a39b4d4ed3a485b466f0770af6 --- /dev/null +++ b/interpro_repeat/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d15271d07a0b16180a68f788b0a3344b3ff96022e8c15f0dac21340f6fe60fb6 +size 151008 diff --git a/interpro_repeat/consensus.joblib b/interpro_repeat/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..d06cfddc8f88b428fe1d080ae42146b10f4aaea8 --- /dev/null +++ b/interpro_repeat/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ca48d6a2d87efd51852c20527c7836c814fef83747bc7e0b480cce1bbcb292ba +size 79937 diff --git a/interpro_repeat/df_merge.tsv b/interpro_repeat/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..b6ad69bd8580c535598ddbad2cb8b7a409d1906a --- /dev/null +++ b/interpro_repeat/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Mitochondrial substrate/solute carrier [IPR018108] 8 20 3.064744677101647 0.0021785589299352 9.148058252427184 20.71359223300971 2.0411027534642088 0.1411881998864352 5.368907349966936 1.8276489510009888 1.309103123363054 0.2428184236965967 1.141599058742867e-05 0.0008295914112261 3.035452872698047e-05 0.0002799919034951 6.734850608491655e-05 diff --git a/interpro_repeat/metrics.json b/interpro_repeat/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..fba52cb446652d604d38e0f79cb05f7e5f0e2a09 --- /dev/null +++ b/interpro_repeat/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3329, + "annotations_size": 81, + "title": "Average number of proteins per term", + "value": 5.617283950617284 +} \ No newline at end of file diff --git a/interpro_repeat/paths.json b/interpro_repeat/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..09bc88b70a3825ac5163d58d1a819161b08f4b42 --- /dev/null +++ b/interpro_repeat/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_repeat/fragment/C342/C342_val_log2fc"} \ No newline at end of file diff --git a/interpro_repeat/result.tsv b/interpro_repeat/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..1ce04773c1acecfc1a0c194394a22243086b1ecc --- /dev/null +++ b/interpro_repeat/result.tsv @@ -0,0 +1,10 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mitochondrial substrate/solute carrier [IPR018108] 0.7748299248894673 3.064744677101647 0.0021785589299352 0.1619317775483078 0.1511157703247947 20 Q9BSK2,Q9H2D1,Q9Y619,P12235,Q02978,O43772,Q70HW3,Q9Y6C9 8 +HEAT repeat [IPR000357] 0.6770517318230789 1.657126777855225 0.0974938463247698 0.9997537002815736 0.3323570586576909 8 P30154,P30153 2 +PFTB repeat [IPR001330] 0.8962717979554964 1.3736932550204612 0.1695369317619155 0.9999997082934304 0.4208975428294725 3 P53609,P49356 2 +Tetratricopeptide repeat 1 [IPR001440] 0.548430532485932 1.1505581255769002 0.2499140684453853 0.9999999999234416 0.4937326718067368 10 Q02790 1 +HEAT, type 2 [IPR021133] 0.4991512442259591 1.067207243926122 0.2858782621754598 0.9999999999985691 0.5069294400699529 13 P30154,Q9P260,P30153 3 +Hexapeptide repeat [IPR001451] 0.7239927841250613 0.7482575931525188 0.4543047980544235 1.0 0.6896347285921121 3 Q9Y5P6,Q13144 2 +Kinesin light chain repeat [IPR015792] 0.723090799759462 0.745164326902814 0.4561723854095447 1.0 0.6896347285921121 3 Q07866,Q9H0B6 2 +Tetratricopeptide repeat [IPR019734] 0.333130592211342 0.6004744643068266 0.5481900741558701 1.0 0.752599932315686 50 Q6ZXV5,P13674,Q6P2P2,A0AVF1,Q02790,Q6PGP7,Q07866,Q13451,Q9UJX3,Q6DKK2,O15460 11 +Sel1-like repeat [IPR006597] 0.5042146559705811 0.160577840070773 0.8724259094399367 1.0 0.9422199821951316 3 Q9UBV2 1 diff --git a/interpro_repeat/selections.json b/interpro_repeat/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..330c09543d43996742d6096bf0a1fedf31aaae65 --- /dev/null +++ b/interpro_repeat/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Adenomatous polyposis coli (APC) repeat [IPR041257]", "Adenomatous polyposis coli protein repeat [IPR009223]", "Adenomatous polyposis coli protein, 15 residue repeat [IPR009240]", "Ankyrin repeat [IPR002110]", "Annexin repeat [IPR018502]", "Armadillo [IPR000225]", "Atypical Arm repeat [IPR032413]", "BIR repeat [IPR001370]", "Calponin repeat [IPR000557]", "Cation-independent mannose-6-phosphate receptor repeat [IPR000479]", "Chromosome region maintenance repeat [IPR041123]", "Clathrin, heavy chain, propeller repeat [IPR022365]", "Clathrin, heavy chain/VPS, 7-fold repeat [IPR000547]", "Collagen triple helix repeat [IPR008160]", "Cysteine-rich Golgi apparatus protein 1 repeat [IPR001893]", "Cysteine-rich Golgi apparatus protein 1 repeat, eukaryote [IPR017873]", "Exportin-1, repeat 2 [IPR041235]", "Exportin-1, repeat 3 [IPR040485]", "Filamin/ABP280 repeat [IPR001298]", "Filamin/ABP280 repeat-like [IPR017868]", "Fis1, C-terminal tetratricopeptide repeat [IPR028061]", "Fis1, N-terminal tetratricopeptide repeat [IPR028058]", "Furin-like repeat [IPR006212]", "G-protein beta WD-40 repeat [IPR020472]", "GTF2I-like repeat [IPR004212]", "HAT (Half-A-TPR) repeat [IPR003107]", "HEAT repeat [IPR000357]", "HEAT repeat associated with sister chromatid cohesion protein [IPR026003]", "HEAT, type 2 [IPR021133]", "HUWE1/Rev1, ubiquitin binding region [IPR025527]", "Hexapeptide repeat [IPR001451]", "Hs1/Cortactin [IPR003134]", "Huntingtin, middle-repeat [IPR024613]", "Importin repeat 4 [IPR041653]", "Importin repeat 6 [IPR041389]", "Importin repeat [IPR040928]", "KI67R [IPR012568]", "Kelch repeat type 1 [IPR006652]", "Kelch repeat type 2 [IPR011498]", "Kinesin light chain repeat [IPR015792]", "LDLR class B repeat [IPR000033]", "Leucine rich repeat 4 [IPR025875]", "Leucine-rich repeat [IPR001611]", "Leucine-rich repeat, cysteine-containing subtype [IPR006553]", "Leucine-rich repeat, typical subtype [IPR003591]", "Low-density lipoprotein (LDL) receptor class A repeat [IPR002172]", "MORN motif [IPR003409]", "Mbt repeat [IPR004092]", "Microtubule associated protein, tubulin-binding repeat [IPR001084]", "Mitochondrial substrate/solute carrier [IPR018108]", "NHL repeat [IPR001258]", "Nebulin repeat [IPR000900]", "Neuraxin/MAP1B repeat [IPR000102]", "P120R repeat [IPR012586]", "PBS lyase HEAT-like repeat [IPR004155]", "PFTB repeat [IPR001330]", "Paired amphipathic helix [IPR003822]", "Parallel beta-helix repeat [IPR006626]", "Pentatricopeptide repeat [IPR002885]", "Plectin repeat [IPR001101]", "Proteasome/cyclosome repeat [IPR002015]", "Protein of unknown function DM15 [IPR006607]", "Protein prenyltransferase, alpha subunit [IPR002088]", "Proteinase inhibitor I27, calpastatin [IPR001259]", "Pumilio RNA-binding repeat [IPR001313]", "Putative TPR-like repeat [IPR031545]", "Pyrrolo-quinoline quinone repeat [IPR002372]", "RNA helicase p68 repeat [IPR012587]", "RNA polymerase II, heptapeptide repeat, eukaryotic [IPR000684]", "Regulator of chromosome condensation, RCC1 [IPR000408]", "SAMP [IPR009224]", "Sel1-like repeat [IPR006597]", "Spectrin repeat [IPR002017]", "Spectrin/alpha-actinin [IPR018159]", "Tetratricopeptide repeat 1 [IPR001440]", "Tetratricopeptide repeat 2 [IPR013105]", "Tetratricopeptide repeat [IPR019734]", "Vesicle tethering protein p115, armadillo tether-repeat [IPR041209]", "WD40 repeat [IPR001680]", "Wolframin, Sel1-like repeat [IPR045458]", "Zinc finger, C2H2C-type [IPR002515]"], "available_proteins": ["AAAS", "AAMP", "ACTN1", "ACTN2", "ACTN4", "AGAP3", "AIP", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKRD17", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP2B1", "APC", "ARMC1", "ARMC6", "ARMCX3", "ARPC1A", "ARPC1B", "ARVCF", "ASB6", "ASPH", "BCOR", "BIRC6", "BOP1", "BRAT1", "BUB3", "CAST", "CDC23", "CDC27", "CHAF1B", "CKAP5", "CLASP1", "CLPB", "CLTC", "CNN2", "CNN3", "COA7", "COLEC12", "COPA", "COPB2", "CORO1B", "CORO1C", "CRNKL1", "CSTF1", "CSTF3", "CTNNB1", "CTNND1", "CTR9", "CTTN", "DCAF7", "DCAF8", "DDX5", "DNAAF5", "DNAJC3", "DNAJC7", "DOHH", "DSP", "DST", "DTL", "DYNC1I2", "EDC4", "EGFR", "EHMT2", "EIF2B5", "EIF3I", "ELP2", "EMC1", "EMC2", "EML4", "EPPK1", "ERBIN", "FIS1", "FKBP4", "FKBP5", "FKBP8", "FLII", "FLNA", "FLNB", "FLNC", "FNTA", "FNTB", "GCN1", "GEMIN5", "GLG1", "GLS", "GMPPA", "GMPPB", "GPSM1", "GRWD1", "GTF2I", "GTF3C2", "GTF3C3", "HCFC1", "HECTD1", "HERC4", "HTT", "HUWE1", "IFIT5", "IFT88", "IGF1R", "IGF2R", "ILK", "IPO4", "IPO5", "JUP", "KAT7", "KDELC2", "KDM2A", "KIAA1468", "KLC1", "KLC2", "KLC4", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "LARP1", "LASP1", "LDLR", "LLGL1", "LRBA", "LRCH2", "LRP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC59", "LRWD1", "MACF1", "MAP1B", "MAP4", "MED16", "MKI67", "MKLN1", "MRPS27", "MTCH1", "MTCH2", "MYCBP2", "NAA15", "NAA16", "NASP", "NEK9", "NFKB1", "NHLRC2", "NIPBL", "NISCH", "NLE1", "NOL10", "NOP2", "NOP9", "NUDT12", "NUP214", "NUP37", "NUP43", "NXF1", "OGT", "P4HA1", "P4HA2", "PAFAH1B1", "PAK1IP1", "PDCD11", "PEX5", "PGGT1B", "PHIP", "PIK3R4", "PLAA", "PLEC", "PLRG1", "POLR2A", "PPID", "PPP1R12A", "PPP1R7", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP4R1", "PPP5C", "PPWD1", "PREB", "PRKCSH", "PRMT9", "PRPF19", "PRPF39", "PRPF4", "PRPF6", "PSMD1", "PSMD10", "PSMD2", "PTCD1", "PTCD3", "PUM1", "PUM3", "PWP1", "PWP2", "RABEPK", "RABGGTA", "RABGGTB", "RACK1", "RAE1", "RAI14", "RANBP2", "RANBP6", "RANGAP1", "RAP1GDS1", "RBBP5", "RBBP7", "RCC1", "RCC2", "RPAP3", "RPTOR", "RRP9", "RSU1", "SART3", "SCML2", "SCRIB", "SEC31A", "SEH1L", "SEL1L", "SETD7", "SGTA", "SHCBP1", "SHOC2", "SIN3A", "SKP2", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A5", "SLC25A6", "SLIT2", "SMU1", "SNRNP40", "SNRPA1", "SPTAN1", "SPTBN1", "SPTBN2", "SRP72", "STIP1", "STRAP", "STRN", "STUB1", "SUGT1", "SYNE1", "SYNE2", "TAGLN2", "TBL1XR1", "TBL2", "TBL3", "TEX10", "THOC3", "THOC6", "TMTC3", "TOMM34", "TOMM70", "TPBG", "TRIO", "TTC1", "TTC19", "TTC26", "TTC27", "TTC28", "TTC37", "TTC4", "UNC45A", "USO1", "UTP15", "UTP18", "UTP4", "UTP6", "UTRN", "VPS18", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR36", "WDR4", "WDR41", "WDR43", "WDR45B", "WDR46", "WDR48", "WDR5", "WDR6", "WDR61", "WDR70", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WRAP53", "WRAP73", "XAB2", "XPO1", "YTHDC2"], "leading_proteins": ["ANAPC7", "EIF2B5", "FKBP4", "FKBP5", "FNTB", "GMPPB", "KIAA1468", "KLC1", "KLC2", "MTCH2", "P4HA1", "P4HA2", "PGGT1B", "PPP2R1A", "PPP2R1B", "PRMT9", "SEL1L", "SLC25A11", "SLC25A15", "SLC25A20", "SLC25A26", "SLC25A32", "SLC25A33", "SLC25A4", "TMTC3", "TTC19", "TTC26", "TTC37"]} \ No newline at end of file diff --git a/msigdb_gobp/advanced/idx2term.json b/msigdb_gobp/advanced/idx2term.json new file mode 100644 index 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0000000000000000000000000000000000000000..1801aea2cdffbe047e4ee4d8299d67922d42fbd9 --- /dev/null +++ b/msigdb_gobp/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3324ff93a6de3b2c666b592589734d22bf62ff65a2e674bb2a9750f288835b84 +size 352561 diff --git a/msigdb_gobp/df_merge.tsv b/msigdb_gobp/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..fa1c22fd7efff65022b1513022b70025112a16df --- /dev/null +++ b/msigdb_gobp/df_merge.tsv @@ -0,0 +1,137 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Mitochondrial transmembrane transport 11 51 3.602729484876046 0.0003148931880856 19.070388349514563 50.63834951456311 1.9310146760091371 0.188342667216329 9.760351579527285 3.939196260509299 1.9786128158557912 0.3017981993827387 2.021586202224901e-08 0.0007736613442574 8.042615486473851e-09 1.187215610808348e-07 2.84609908758338e-06 +Membrane lipid metabolic process 17 40 3.329388212171079 0.0008703699547558 15.813106796116504 37.71116504854369 1.423850539998867 0.1808469841706369 6.252884620395072 4.742042041181393 2.289538519382486 0.2724480316274368 1.0 1.0 0.3253711362877511 0.0006728024796622 1.9390166381822235e-05 +Secondary alcohol metabolic process 11 44 3.281940155885195 0.0010309548259599 12.097087378640778 42.24514563106796 1.5200936296432006 0.2566232504859334 4.463475425703621 3.883072640851752 1.3223501002339118 0.3210874999447533 5.381139178167896e-06 6.309554266185252e-05 2.0355984891722303e-05 1.1575291859834356e-06 0.0002853261524321 +Anion transport 25 64 3.2804322834858444 0.0010364814270618 26.953883495145632 69.53155339805825 1.854216838065017 0.2425457725148559 12.138973160217668 8.434296289414672 2.014686633079497 0.3448588040224388 0.0212860048767533 0.6295124465651736 0.0131062901023331 0.0096909698873961 0.0041733233537355 +Organic acid transmembrane transport 12 28 3.264749105043484 0.0010956107647461 12.37621359223301 29.983009708737864 1.9038035525846064 0.1759244630123113 6.520447095353999 3.550222565141749 1.416714921004232 0.2641413901650407 0.0004214164597846 0.0584635742500571 0.0001210763991392 0.0001326331665024 0.0001200537537767 +Sphingolipid metabolic process 15 31 3.2602945527920366 0.0011129656512396 12.631067961165048 29.174757281553397 1.3566630100256978 0.1614907042591146 4.986857078326301 3.461093559903884 2.232073980338918 0.2503191978902473 1.0 1.0 0.2318437245510384 9.09669045488998e-05 1.1048981208640522e-05 +Peptidyl proline modification 10 34 3.2356708284224487 0.0012135724425852 7.95873786407767 32.38106796116505 0.6521103584457676 0.5266525958057561 3.2591538539789924 3.194797169860135 0.931894104733149 0.3508680261875629 4.050574015602871e-05 3.745017516645138e-06 7.178515274085645e-06 1.8194218069499183e-08 4.010944532638898e-07 +Mitochondrial transport 21 85 3.177210960128844 0.0014869882872672 26.76456310679612 83.42233009708738 1.9353944346565397 0.260698067067068 11.29934298946582 6.8259418360610375 1.9296757414965091 0.3685496297416806 0.0003766524856744 0.0092751908978721 0.0002295533620845 3.409829331470762e-06 2.2263626134653347e-06 +Organic acid transport 16 44 3.173144124460666 0.0015079764624428 16.199029126213592 46.1626213592233 1.6912598339530378 0.23494744574913 7.685833584742487 5.405881453891157 1.4084922190667013 0.315570201131532 0.004608776861911 0.145012854682081 0.0021256224119551 0.0062007872998891 0.0003565015202922 +Anion transmembrane transport 17 37 3.1007810198932204 0.0019301096981056 18.02912621359223 42.29854368932039 1.9137296804814252 0.1915609440243116 8.771596162415214 5.032004157423188 1.8922368499585025 0.2935375719655638 0.0019301637789318 0.4251307382490726 0.0007513023635316 0.0016033636093166 0.00312498831362 +Alcohol biosynthetic process 11 39 3.091310467309319 0.0019927515518238 9.344660194174756 36.09466019417476 1.0726679306851277 0.3539682718575088 3.792896481514287 3.1078151772256564 1.1587776417647702 0.3419459456532639 0.0006536060964186 0.0008814481157451 0.0002051469607709 1.3117454850314476e-06 0.0003202020297963 +Regulation of blood pressure 6 20 3.006301568920256 0.0026444658830222 5.762135922330097 17.737864077669904 1.3077123393993415 0.1882731913471478 2.2751770017499977 2.3871059987956724 1.372929386780725 0.2480453688154592 0.00113234821195 0.0327224420542492 1.9365416425095668e-05 0.0004830692131202 0.006819962442172 +Protein peptidyl prolyl isomerization 6 25 2.986752683730093 0.0028195771927146 5.805825242718447 24.152912621359224 0.2517409431057898 0.5902438884006979 3.2955051837407017 2.757763315973305 0.91993420852781 0.3179002106692878 0.0028553736551158 0.0007069993740851 0.0003881131251702 2.11392463263383e-05 0.0002756370905093 +Sterol biosynthetic process 7 24 2.969015198494787 0.0029875581945808 7.281553398058253 24.52912621359223 1.190088798384403 0.3136799329736269 3.292879861326439 2.61838648411319 1.1232845583768152 0.3105481837594456 0.0005085746880123 0.0015459220949256 0.0010831329822185 1.5145617231215406e-05 0.0017870110754962 +Organic anion transport 12 41 2.844344734270779 0.0044502869578209 18.575242718446603 46.57281553398058 1.6158560948583975 0.2692356013040078 9.46386426798458 5.9518324529926545 1.7470285445738305 0.3371920110610632 0.1065950705292102 0.5097893650742695 0.0513626688490587 0.0617533503296385 0.023744555101625 +Ceramide metabolic process 10 21 2.8297060673412635 0.0046590785831106 8.191747572815533 19.060679611650485 1.0632949889077032 0.1865092544415649 3.2982239784478966 2.5917545738626013 1.8901201919357584 0.2494992632187684 1.0 1.0 0.1057169178564165 0.0025056010914147 8.069893048129362e-05 +Membrane lipid biosynthetic process 10 25 2.810745568181792 0.0049426854689356 8.866504854368932 23.050970873786408 1.3229385051208649 0.2431293012321725 4.229937732502716 3.4850337476777224 1.635527795490498 0.2996124846932806 1.0 1.0 0.552149589688304 0.0492274998504545 0.0020373428674598 +Sphingolipid biosynthetic process 8 18 2.778440156613806 0.0054620573382377 6.543689320388349 16.33252427184466 1.3108583596388097 0.2293036031089034 3.2058099533310203 2.4273143169149307 1.5209865792019848 0.2861850290041513 1.0 1.0 0.4386006499544391 0.0140792558459456 0.0020871036531804 +Protein targeting to mitochondrion 12 49 2.7455017332029503 0.0060418448328742 14.980582524271844 46.067961165048544 1.7767024064550243 0.249920045184344 6.494927942714517 4.708517660750424 1.5433015545903224 0.3384144763122346 0.0327202076770251 0.0691107257825923 0.0104695800354931 5.159307476616943e-05 8.411916762740673e-05 +Carboxylic acid transport 11 33 2.7322302805368777 0.0062907155238873 12.351941747572816 33.69417475728155 1.517249458545343 0.2522623764771551 6.23371050940395 4.11174791553619 1.419876490432768 0.3135855212793009 0.05084081469667 0.4047844567784328 0.0189557671296911 0.0139947108089724 0.0050359508578095 +Negative regulation of transmembrane transport 5 24 2.7097645505410006 0.0067330985836135 4.915048543689321 20.038834951456312 0.539232326403696 0.5077941070021844 2.6236539308948164 2.892649976298608 0.8428552268580063 0.3052620790205636 0.0916863952751726 0.270648213584465 0.1279708837725801 0.0699868221578369 0.0913317871121833 +Sterol metabolic process 9 39 2.700384141458883 0.0069259455305945 11.932038834951456 38.44660194174757 1.1656335789111734 0.2523239777622673 4.346099994655023 4.0619669904912925 1.6676089351046874 0.3062687621764124 0.0005574995400017 0.0007736613442574 0.0013844952123512 3.812521632033891e-05 0.0027222229885513 +Organic hydroxy compound biosynthetic process 11 56 2.6882167176808185 0.0071834758175537 12.42233009708738 52.37135922330097 0.7934054609743442 0.424605725297311 4.713262264354627 5.1877801804871915 1.1130427360157376 0.3580104692277669 0.0038094241881354 0.0037957594816866 0.0016933870815106 8.041571406937986e-05 0.0047105059781597 +Organophosphate ester transport 5 25 2.684820127923276 0.0072568849400647 10.29126213592233 27.364077669902912 1.4948680330369015 0.1889391065154625 4.84293313185659 4.31957284765524 1.6451867819665518 0.2532208690981375 0.0035360758294857 0.3228460923172884 0.0072060328618288 0.0430672573908121 0.0904421255685502 +Protein localization to mitochondrion 19 64 2.6808570238798604 0.0073433883762297 18.37621359223301 58.6747572815534 1.743973973786015 0.2835887708870952 7.329731795051445 5.553888141183353 1.6030721833013164 0.3628376459321563 0.0544539880271363 0.0981576694070633 0.0207919883966976 1.158307428973248e-05 2.171942012005336e-07 +Cellular modified amino acid metabolic process 13 58 2.667864270729387 0.0076335089230199 11.769417475728156 55.109223300970875 0.5417393674023022 0.4787227552157201 4.409030522246627 4.352235490603726 0.9985496768715664 0.3360934244236461 3.014280747320985e-05 0.1058856107488554 1.3774287662883636e-06 5.654911156287243e-07 3.163860439865914e-05 +Protein transmembrane transport 5 24 2.658335493729344 0.007852767743447 8.992718446601941 25.191747572815533 1.6893060623430327 0.189108476986505 4.473486660459625 2.7693940759543416 1.4682653164365471 0.2783169275392022 0.000805354398294 0.027703186905031 0.0017009652209114 0.0017183337360303 0.0433996585313532 +Alcohol metabolic process 14 88 2.632208077756613 0.0084831890117225 19.300970873786408 81.99029126213593 1.0392616248309592 0.3936245775900834 6.9548962308345 7.403089286448431 1.208378917036781 0.3759976884392474 0.0002430033317269 0.0005171634979467 0.0001888334389749 0.0001754210502201 0.0066859536199895 +Amyloid precursor protein catabolic process 3 21 2.6318633531991487 0.0084918009411683 4.62621359223301 16.47087378640777 1.203006467000838 0.2754962460876 2.1329801006381106 2.1803683249886516 0.947433834000198 0.2709877848980267 0.0475672289294156 0.0195557545343205 0.0678620701894922 0.0216647555097342 0.061872997913683 +Steroid biosynthetic process 8 46 2.5541664523732712 0.0106442358091496 11.728155339805824 44.80825242718446 0.9874364787035632 0.3935759881445143 5.016369659264937 4.35272817633461 1.2862817592315925 0.3680333006848349 0.0073240711493082 0.0118439766153403 0.0145653075103282 0.000571369581492 0.007519358877931 +Negative regulation of ion transmembrane transport 2 19 2.5482196869645235 0.010827426282002 3.851941747572816 15.769417475728156 0.5591127282390159 0.4901790245134628 2.193308693671018 2.0873490063373943 0.8555485550788116 0.3017041398323139 0.0495288874572315 0.1988423464133734 0.0705821305211966 0.0958173315210673 0.1758221500942633 +Amyloid precursor protein metabolic process 3 24 2.515751264467594 0.0118778977441256 5.91747572815534 20.04368932038835 1.2306110398413417 0.2828388345239639 2.574706211328507 3.0661056512526157 1.0127867956133585 0.2841981221806073 0.0706468314608437 0.0296703391700837 0.0995728547031488 0.0443488880214379 0.1295844377433678 +Mitochondrial respiratory chain complex assembly 17 44 2.512072585050644 0.0120024398896518 14.427184466019416 38.300970873786405 1.6683402305651691 0.229838901803248 5.648441561419256 5.588363345618 1.6629328950455762 0.3088219725228932 0.035621016541285 0.3619523256513019 0.0584891686146332 6.892127383073779e-05 1.5574436059818274e-06 +Steroid metabolic process 12 70 2.5061745278676058 0.0122045361453193 17.82766990291262 66.9247572815534 0.9974586731388552 0.3270410156332073 6.090491666967852 5.93996409793671 1.7133199907504504 0.3720334828404655 0.0079241630825951 0.007032737188996 0.0040548001959955 0.0001081918955919 0.0039372807332148 +Vacuolar acidification 4 9 2.504498597399426 0.0122625091469052 3.4757281553398056 8.922330097087379 1.27407749822917 0.1611429668415415 1.4148632661931722 1.303016071016461 1.4195929612668792 0.2212670077717619 0.1338425639181934 1.0 0.1611939416425752 0.0007989256016515 0.0013736729067174 +Negative regulation of calcium ion transmembrane transport 2 9 2.456420155551055 0.0140328982124566 2.1067961165048543 7.601941747572815 0.9433101814663925 0.3101119054926485 1.594362771690279 1.170758660555987 1.028728108691548 0.2750664841729511 0.0097653835482404 0.0892490045576324 0.0143328298354406 0.0103266247469619 0.012134686324044 +Carbohydrate derivative transport 3 14 2.411054276241777 0.0159064810956646 7.924757281553398 17.024271844660195 1.3665639952580566 0.1869571280171947 4.210097511648942 2.624454303682939 1.5541767319140831 0.2467993156006303 0.0515195155901734 0.2027885470531376 0.0733374275738533 0.100752004546059 0.1856866108969999 +Regulation of phospholipid metabolic process 1 12 2.4087639541536587 0.0160066468605921 1.9296116504854368 9.635922330097088 0.662129324721178 0.4086518494099616 1.5555715225620497 1.3998858739150144 0.9005081411083155 0.2701938615678836 0.0153631225051974 0.1114073342812727 0.0224191931510111 0.1147066696002357 0.3288847005661894 +Retrograde vesicle mediated transport golgi to endoplasmic reticulum 7 32 2.400219826264332 0.0163852286341841 7.771844660194175 26.825242718446603 1.1714448828781496 0.3436005361805324 3.811248488859092 3.450558374586287 1.1733172803389544 0.345676809182098 0.0535385420417476 0.0221396463904123 0.0105712178095962 0.0269134143779454 0.0017870110754962 +Regulation of calcium ion transmembrane transport 6 20 2.3811747525027447 0.0172575229603821 4.381067961165049 20.16747572815534 0.2677941306629663 0.6112981843507423 2.9466009420832906 2.782331640226771 0.7439672131804326 0.2863165715464626 0.1142884986871186 0.3024216363859021 0.1579906452537346 0.2618534741619217 0.1454895561901762 +Protein maturation 13 74 2.373250141229428 0.0176323182024706 16.635922330097088 69.29611650485437 0.7279397561088901 0.5092233260742579 5.6828366082703345 6.923625268615643 1.0037762420957868 0.3621314209884535 0.0216966717485548 0.258876638823261 0.0134061560735493 0.0100383818491439 0.0094817876442611 +Ph reduction 4 13 2.3657371410561225 0.017994215186849 4.422330097087379 12.509708737864075 1.1966830084586066 0.1930048880851129 1.91475781321527 1.7851607614701208 1.4167744165903868 0.2497649393583847 0.2003857556648621 1.0 0.239336332644921 0.0044180066438726 0.0105347068278647 +Cytosolic calcium ion transport 6 23 2.3593444040003835 0.0183072563795065 6.567961165048544 23.944174757281555 0.4634706877593821 0.4616211122842976 3.323605294530572 2.8902732844456565 1.0331628024603872 0.3216839736311487 0.1463220365086775 0.3426841548479852 0.1997425917545389 0.3418417958839898 0.2348598000363222 +Nucleotide transmembrane transport 3 9 2.3525648377611343 0.0186444389974527 4.029126213592233 9.24271844660194 1.3657020532080593 0.1972377481261837 2.230443861436908 1.484326001257553 1.1744026177454787 0.2553979780962895 0.0002510688053124 1.0 0.000453663444764 0.0062969264366488 0.0063986173037271 +Transmembrane transport 45 211 2.3102478327055502 0.0208744372554661 67.45631067961165 211.1359223300971 1.8122664376950308 0.3598356673827246 27.267027885156203 22.354947126810902 2.251277763144546 0.4188333713481413 2.300540483491085e-06 0.0037845582566343 1.1951250479775994e-05 6.332660737784436e-06 0.00043185102309 +Negative regulation of calcium ion transport 2 11 2.299660579575879 0.0214674571012019 2.378640776699029 8.815533980582524 0.865801675063994 0.3348216966365627 1.767376998119782 1.5264501163101216 0.996781239251156 0.2731835761958332 0.0234831618980058 0.1373006943976843 0.03403446937649 0.0356014336373073 0.0564014374232863 +Regulation of amyloid precursor protein catabolic process 2 18 2.2985789348943397 0.0215288608594335 3.8859223300970873 14.189320388349516 0.723751929535891 0.4024575578925681 1.8731873759514015 2.0164571748807374 0.9921534445034136 0.3036488689822377 0.2255660263240682 0.1457663642848915 0.2685353106225043 0.0419909810254146 0.2040147905672061 +Inorganic anion transport 12 22 2.2969297194657976 0.0216227792870575 9.900485436893204 25.351941747572816 1.3590123122148194 0.2025490755989976 4.608697956226863 4.352203003870329 1.5972877171217004 0.2769639658120273 0.1040709913824722 1.0 0.1444798026258102 0.0260351232348132 0.0186989671551434 +Terpenoid metabolic process 4 17 2.296720439296677 0.021634722698814 4.992718446601942 17.42233009708738 0.6301104025923489 0.3704291423404849 2.365292196147205 2.02323551503238 1.1104102314092092 0.2862846297230793 0.0041434552332018 0.1828652209005429 0.0072464589525271 0.0771340965144245 0.0480087672890962 +Cytochrome complex assembly 6 13 2.2874888012067025 0.0221673083560607 5.339805825242719 11.616504854368932 1.5489281771301031 0.1834582376033618 2.45860248431673 2.439266047793512 1.3189185418401956 0.2620853228235733 0.0296748446689961 0.1541506060207377 0.0428134756181982 0.0001479614805466 0.0001802592260071 +Lipoprotein metabolic process 4 20 2.272042678232568 0.0230839327347147 5.504854368932039 19.114077669902912 1.0723975558987071 0.2794846862458811 2.648039342123219 3.7213756556771336 1.2556798055308762 0.2951644225033464 0.4937784552011317 0.3426841548479852 0.1997425917545389 0.152340992243069 0.2348598000363222 +Regulation of cytosolic calcium ion concentration 3 23 2.26942896974868 0.0232422521496944 5.611650485436893 22.90776699029126 -0.0060791040101891 0.6946202958545274 2.813742315775761 2.88808026810663 0.6468386253472025 0.2724733438453219 0.5513512033020112 0.3898210156701354 0.2534337902702077 0.4406224335063978 0.5437080849598914 +Regulation of ph 6 22 2.26866100550326 0.0232889486558858 6.890776699029126 20.859223300970875 1.2151699598837196 0.2373503364294603 2.930458126920059 2.7746402510870145 1.4154672965603718 0.2873526492076106 0.3401863269772942 1.0 0.3986935444378103 0.0083779468893575 0.0126413335687205 +Regulation of cellular ph 6 22 2.26866100550326 0.0232889486558858 6.885922330097087 20.844660194174757 1.215766922704761 0.2375185297794358 2.9319293283093293 2.765976649626597 1.4143296516981956 0.2875299337708636 0.3241278561251733 1.0 0.3807425591652282 0.0065185653530446 0.0091977598518556 +Long chain fatty acid transport 5 13 2.252388912001149 0.0242977058079871 3.4514563106796117 12.980582524271844 1.1347693444093316 0.300255043373995 1.9890654524939184 1.4909473272084874 0.7833838873177712 0.258106472565451 0.0234831618980058 0.1373006943976843 0.03403446937649 0.0356014336373073 0.0028701063805994 +Negative regulation of mrna catabolic process 9 26 2.242944818925059 0.0249003731002557 9.169902912621358 24.631067961165048 0.5652120707700043 0.4958815262040553 4.097153521759381 1.8459627491120816 1.1372403168685192 0.3560626632344691 1.0 1.0 1.0 0.0958173315210673 4.798658441078818e-05 +Negative regulation of transporter activity 1 16 2.241334460127856 0.0250044183907107 4.111650485436893 13.21359223300971 0.2247815310389012 0.5569194596928818 2.4892312132824013 2.101319444192533 0.8931834718774553 0.3061163348813704 0.2736002811127123 0.1788224008957527 0.3236452024265956 0.2541035375726295 0.3103681353614002 +Chaperone mediated protein folding 7 42 2.238855169134573 0.02516534126293 11.118932038834952 38.883495145631066 -0.1029907258602878 0.6564055836771622 6.3893062073213605 1.9941709758805528 0.8301601182731878 0.321599905761079 0.0114100706789716 0.0029741493546945 0.0025290933815156 0.0029882589766175 0.0020871036531804 +Regulation of pattern recognition receptor signaling pathway 3 23 2.238652130436122 0.0251785594844473 4.691747572815534 19.70873786407767 0.80673262224624 0.4173389113947272 2.517825740704142 3.173406084005513 0.919675411949683 0.3119180769844089 0.0130510720508035 0.2633971592089756 0.0222198796395938 0.0637468602571873 0.3591951689526639 +Regulation of lysosomal lumen ph 3 7 2.236238373095613 0.0253361608539972 2.3567961165048543 5.58252427184466 1.1719038900849827 0.159040563248536 1.2351555175791742 1.4280428037740598 1.4707016211600112 0.2132438131163355 0.1128336603904996 1.0 0.1362380906066266 0.005208827916976 0.004988841333209 +Intracellular protein transmembrane transport 4 21 2.231899425803427 0.0256216108569082 7.233009708737864 21.9004854368932 1.450039081018812 0.2247265328975946 3.8281123729210935 2.4627910122818513 1.3220665029303609 0.2876555154826584 0.0053915705605471 0.1988423464133734 0.0093807730237194 0.0045172618985585 0.066946879618907 +Nucleotide transport 3 11 2.229086283652175 0.0258081643662897 6.189320388349515 13.405339805825244 1.3859091987706234 0.2148450774807873 3.399469193898354 2.266957807297256 1.34942986946681 0.2785977875693559 0.0011008240653655 1.0 0.0019631407021181 0.0244664942800011 0.0357999050404339 +Dicarboxylic acid transport 4 14 2.227140354095469 0.0259378949484512 5.718446601941747 16.097087378640776 1.1205667041867788 0.2998586575349944 3.584398436287638 2.226340822602054 1.0973546365412417 0.2986830136605488 0.0437331415032988 1.0 0.0625314301217693 0.0185450998789275 0.0524034739320251 +Vitamin transmembrane transport 4 5 2.2261195499940523 0.0260061747695599 2.9344660194174756 6.094660194174757 1.6910321805591797 0.1136175735100163 1.344920850275403 0.8913122381585616 1.0580472895861666 0.1862049292817703 0.0002051665230549 0.0711332726649859 0.0003712110430798 2.0114332489481176e-05 0.000543833852376 +Vitamin transport 4 5 2.2261195499940523 0.0260061747695599 3.587378640776699 7.597087378640777 1.658661901456128 0.1256251915839625 1.8073839707699664 1.6422194495621811 1.0713624000848283 0.1994200282768667 0.0008668036521605 0.1114073342812727 0.0015498580582828 0.0002379581347217 0.005348590970678 +Membrane protein proteolysis 3 13 2.2169575220247677 0.0266259943924491 4.138349514563107 11.781553398058252 1.0093176076341577 0.3069750059979975 2.078037067185485 1.3902746514167437 1.0484204695389652 0.2877212872591311 0.0400219673851754 0.1788224008957527 0.0067632743899401 0.0157211013123339 0.0438404511308739 +Alternative mrna splicing via spliceosome 20 44 2.2148864563076147 0.0267678589536592 14.009708737864075 40.728155339805824 0.0708159133159534 0.5694011596603432 6.451830696216548 3.032011011191426 1.225863726972057 0.3649890000258197 1.0 1.0 1.0 0.0699868221578369 0.0002387164248667 +Cardiac ventricle development 2 14 2.2101332269190395 0.0270959174555505 3.2063106796116503 14.5873786407767 0.2221474842199061 0.5583095781625196 2.1516891040681405 2.267250146226305 0.8248058772114771 0.288459221960938 0.4601494312789502 0.3161039234082394 0.5295791199213273 0.2883697083877212 0.5229854304103481 +Peptide catabolic process 4 11 2.209152562777285 0.0271640311291012 3.871359223300971 10.351941747572816 1.5413280472635258 0.1625248535751528 1.454973091229298 0.9501768442987896 1.1353491763523988 0.2229381591694359 0.1407357406046216 0.0892490045576324 0.0007685743700876 7.191102350304072e-05 0.0002072021253135 +Regulation of calcium ion transmembrane transporter activity 5 15 2.204013525884431 0.0275233928660596 4.325242718446602 14.907766990291265 -0.0129777133794836 0.6065899940097177 2.5620538805260953 2.0220238501463936 0.79425356338174 0.290397143523548 0.3021147146085102 0.1988423464133734 0.3559802976275766 0.2994428025832826 0.066946879618907 +Folic acid metabolic process 4 7 2.199342858768758 0.0278535523772709 1.91747572815534 7.140776699029126 1.2977645388348351 0.249592124826322 1.215987926650751 0.8615786924829095 0.8405378716662024 0.2600707347072601 0.0001650774091683 0.066549445548378 0.0002990720728516 0.0002821754852333 0.0003776201815095 +Mitochondrial membrane organization 14 49 2.1975584205235315 0.0279805890091133 16.983009708737864 46.91019417475728 1.283632855732258 0.3380738792929293 7.413069190635445 4.027718639381892 1.6948461264793506 0.367302285357348 0.1770920503207587 0.3775853910008817 0.2390296323992287 0.2054309993859782 0.0007542114954339 +Protein transmembrane import into intracellular organelle 3 13 2.1970990654877034 0.0280133718517503 4.951456310679611 13.45631067961165 1.503963012554726 0.1758225015375162 2.735521961789203 1.4944992929031071 1.2360761671845495 0.245991671368161 0.0234831618980058 0.1373006943976843 0.03403446937649 0.0056932223374956 0.0564014374232863 +Calcium ion transport into cytosol 2 14 2.191768415169717 0.0283962328387867 4.182038834951456 14.919902912621358 -0.0995773154487918 0.6085191455752748 2.3178010415897994 2.2941233472334512 0.7893443554894826 0.2904291979836192 0.4196745331674308 0.2849410889163232 0.4860789703868964 0.4955518992738811 0.6522913756747303 +Negative regulation of ion transport 2 23 2.191544157501685 0.0284124379339831 4.305825242718447 17.961165048543688 0.4728123932912365 0.5347351167550078 2.468965635497124 2.7770639314850305 0.7945923921958079 0.3001488807001568 0.0941265909541163 0.2742474624411909 0.1312354716944213 0.2100263434971256 0.3928956555746815 +Protein maturation by protein folding 1 7 2.1888541988802936 0.0286074389291837 1.800970873786408 5.606796116504855 0.2039227563463828 0.5758862077366389 1.3050309779927047 0.6760482168020482 0.8062345922922312 0.2829153992075399 0.0021644162661245 0.0432957136582515 0.0032139762811053 0.0189506401306209 0.0682492372420068 +Positive regulation of i kappab kinase nf kappab signaling 3 39 2.188225405077458 0.0286531874227145 7.344660194174757 35.86407766990291 0.4790737148931881 0.5397451864543208 3.344702467076835 5.27321228840899 0.8885741992578381 0.3336801499419705 0.0771449781684952 0.4611241633653626 0.1215759638014328 0.3619411972926146 0.5765200824108987 +Protein hydroxylation 5 16 2.1790946306531183 0.0293246390609858 5.04126213592233 14.87621359223301 0.7765678108992397 0.4273021352291809 2.482119818897232 1.8660787070180411 0.9906439819977368 0.3285418073460514 0.0153631225051974 0.0060718409625537 0.0224191931510111 0.0002379581347217 0.000834425134113 +Fatty acid transmembrane transport 2 6 2.174133074367442 0.0296951427077099 2.3519417475728157 6.720873786407767 1.487456141723218 0.1763040127694548 1.5547987465385102 1.1092073674791965 0.7935702169981724 0.2103298472796338 0.0039071928268104 0.0573151884822011 0.0057815105752346 0.0026581093268102 0.0183139901045195 +Negative regulation of cation channel activity 1 8 2.1720535616719694 0.029851623128889 2.133495145631068 6.012135922330097 0.3843341472061108 0.4773896383730598 1.4478455428656238 1.1179681209181225 0.991066221927023 0.3079680390661607 0.1338425639181934 0.0847528009868792 0.1611939416425752 0.0698282842903305 0.0547354250806853 +Macromolecule depalmitoylation 3 6 2.171787251702149 0.0298717136971113 1.91747572815534 5.429611650485437 0.9780254626091984 0.222941388490727 1.137611804765983 0.8139540579221628 1.3123017012345466 0.2566673774233151 0.091321621191287 0.0573151884822011 0.0057815105752346 0.0001450038876457 0.0020333503076747 +Negative regulation of ion transmembrane transporter activity 1 14 2.147110892608151 0.0317844543317027 3.817961165048544 11.861650485436892 0.3764600221454999 0.5118077234396127 2.3889648646862596 1.939068236399221 0.964288359393085 0.3191649145735881 0.2378608432520957 0.1541506060207377 0.2827159209662828 0.2000228109389489 0.229933672353323 +Heart morphogenesis 5 27 2.145907762193283 0.0318803383997086 5.939320388349515 27.385922330097088 0.0494067409377516 0.5751291145652665 3.1024117652930885 3.801391655465039 0.8382461615504733 0.2895731451836476 0.6905293491478519 0.5146542249230733 0.7618415975352684 0.476649182034557 0.7241506691796201 +Regulation of cation channel activity 5 18 2.1268898427064027 0.0334292370069537 4.62621359223301 17.271844660194176 0.0934351855766884 0.5741768920956958 2.366040531994021 2.503179239680337 0.8688244316006214 0.3010087737996335 0.4149963521590031 0.2813938178053637 0.4810063700036922 0.4877184600960113 0.2285487004354137 +Calcium ion transmembrane transport 9 38 2.118484088088094 0.0341340910962264 10.5 40.51456310679612 0.3400819096715784 0.5565528717247777 4.784430655681941 4.7513188310580725 0.9547513033794968 0.3464854172738558 0.2822931217950943 0.4795806297081992 0.3677919995773345 0.400696578186417 0.1963230713102622 +Regulation of toll like receptor signaling pathway 1 11 2.118298667677398 0.0341497814070137 2.587378640776699 9.50485436893204 0.9772136844316576 0.3297728067967737 1.666236944633112 1.8466647258935645 0.9012634534298872 0.2761306672489575 0.0437331415032988 0.1868885334554594 0.0625314301217693 0.2722557910873528 0.6152256119482173 +Fatty acid transport 5 16 2.115074265062486 0.0344236182137154 4.405339805825243 16.594660194174757 0.9956425124175664 0.363449355794835 2.458050105556273 1.867782713051167 0.7812672834370499 0.2834143639149277 0.0400219673851754 0.1788224008957527 0.0573531962335191 0.072741111398958 0.0122973883017787 +Protein quality control for misfolded or incompletely synthesized proteins 3 12 2.11374416575529 0.0345371240916545 2.79126213592233 12.0 0.5975496500899943 0.4916109553523294 2.034918800227117 1.0096620601608022 0.8606428606135228 0.3201479866678081 0.1939653795966551 0.1244478155008913 0.2318581098993339 0.1392702662277763 0.0404595824929281 +Cellular hormone metabolic process 3 17 2.110763943767618 0.0347926067162172 5.441747572815534 17.32766990291262 0.9908884218524354 0.2940959275691314 2.8170777488519256 1.7185203072340225 1.2515909253444888 0.3031653223897966 0.3348758234497109 1.0 0.0132042256106822 0.034999603504981 0.2373860395762566 +Protein refolding 0 13 2.0994409331211044 0.0357780495472115 3.6092233009708736 11.230582524271844 -0.1361358621145344 0.6481262090313329 2.583595067809296 0.9335892999889308 0.6822296736077167 0.2695633823034391 0.1338425639181934 0.0847528009868792 0.1611939416425752 0.3582816735878424 0.5942978505128852 +Negative regulation of mrna metabolic process 21 47 2.097562589879083 0.0359438027147569 15.78640776699029 45.30339805825243 0.4317654752348391 0.5186468695555119 6.004287279655988 2.910090931551649 1.3207774317424965 0.3775544483756486 1.0 1.0 1.0 0.0305893198626631 3.861621757845318e-05 +Negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway 0 16 2.096528101957969 0.0360353697224238 3.70873786407767 13.225728155339803 0.1207945387582695 0.6056782907647003 2.351950514476632 2.015719343011274 0.8095159596863328 0.2961773927622835 0.3861348376523477 0.2597451867723493 0.4495131201040838 0.7783274577470375 0.8060805939738915 +Dna replication checkpoint signaling 1 7 2.095685050614709 0.0361101388614391 1.4014598540145986 5.343065693430657 0.4070221385927607 0.5031439638432396 1.3515415404244602 1.6818971280835409 0.9032965444416626 0.3024588914025314 0.1198919526526125 0.0756950383436983 0.144637307685789 0.0565188023636715 0.1824124195300006 +Neuron apoptotic process 18 49 2.089399193129314 0.0366718038067053 11.191747572815531 49.65533980582524 0.9007291731588002 0.4299023129629146 4.0102574614548505 4.518854312987721 0.9862249081516458 0.3541854094791909 0.69549797466159 1.0 0.7665107944697891 0.0693781675257684 0.1085305944230471 +Pteridine containing compound metabolic process 5 18 2.088222588157487 0.0367777606424184 3.83495145631068 17.62864077669903 0.7459938330774762 0.4836011399422016 2.590487030636505 1.3813793223165276 0.7670194449127248 0.3150925598502537 0.0016801534153067 0.1373006943976843 0.0001888015632795 0.0007082692598358 0.0004849181964336 +Sequestering of calcium ion 2 17 2.0876595555158426 0.0368285556125493 5.12621359223301 17.20631067961165 -0.2130074812079837 0.6416352506530011 2.9729512376045584 1.957970759667056 0.6966580842239374 0.2865441629105967 0.3910409134360603 0.2633971592089756 0.4548903476361624 0.447448107055433 0.5895094123606006 +Cellular monovalent inorganic cation homeostasis 6 26 2.0861848034447057 0.0369618862483962 8.191747572815533 25.12378640776699 1.1978511848260835 0.2636491484517694 3.558748260132903 2.9783551257949803 1.4212259473978417 0.3021468238591936 0.3861348376523477 1.0 0.4495131201040838 0.016092475953857 0.0283917079041131 +Lysosomal lumen acidification 2 5 2.0669491474188497 0.0387389459561822 1.9077669902912624 4.094660194174757 1.0430284513288333 0.1731957374320673 1.0102570393282595 1.1504623937719378 1.495459416196642 0.2154807950267566 0.0840370854942358 1.0 0.1018169846714528 0.0280420066437826 0.0142438301551866 +Isoprenoid metabolic process 4 22 2.066480605086002 0.0387831218805569 6.351941747572815 23.436893203883496 0.371913197601784 0.4325927382253215 2.8701546111232905 3.133501725907374 1.111400072689174 0.3110459828013394 0.009418704937411 0.237457799625543 0.0161789595718159 0.1492939653041362 0.1295844377433678 +Metal ion homeostasis 19 77 2.0657325519177303 0.0388537398461816 22.37864077669903 79.5 0.7762327689006491 0.4501210966631583 8.485414676383348 8.298876985671072 1.3957415688189287 0.3857448193070677 0.3478628679753505 0.3711009128414778 0.2521638838884718 0.3099392767434266 0.145193174871593 +Blood vessel endothelial cell migration 3 24 2.063356405470852 0.0390787786338653 4.536407766990291 22.449029126213592 0.7681724367497832 0.3963490094539818 2.4704338498615206 2.406468634828595 1.0319905271466427 0.3120666413936225 0.0180567941532142 0.046072228335376 0.0304335118961749 0.0904947271532713 0.1260437200975292 +Protein depalmitoylation 2 5 2.061242497052852 0.0392799110712491 1.3203883495145632 4.468446601941747 0.9114659728007516 0.274733419943775 1.0188856680336909 0.6320520706114182 1.1467191069327447 0.2583665413440971 0.0766948790541844 0.0479914252810258 0.0039921150854813 0.0015031185668187 0.0107435842434709 +Positive regulation of protein binding 2 23 2.057656036210714 0.0396231634246988 5.099514563106796 23.00242718446602 0.3155864476850776 0.5869976520948652 2.6175842559823277 2.8459635752908654 0.8435085117004013 0.3185282020054304 0.0154386503233886 0.2778293030066073 0.0261522178742545 0.2163833685942582 0.102256923222589 +Glycerophospholipid catabolic process 2 9 2.0530824790607225 0.0400645789279137 2.216019417475728 7.563106796116505 0.8419758607208171 0.2558936783676348 1.405411068501889 1.391164232085279 1.2384126210044872 0.2497846504551273 0.1198919526526125 0.0756950383436983 0.000453663444764 0.0062969264366488 0.0403506671570748 +Neutral lipid biosynthetic process 1 7 2.052920921005203 0.0400802476298534 2.1067961165048543 6.288834951456311 1.1186547336258812 0.1821371148552785 1.2515048910859687 1.3298556757746482 1.2887117600293918 0.213034599641239 0.1939653795966551 0.1244478155008913 0.0279813079733609 0.1392702662277763 0.3827254031641982 +Negative regulation of transforming growth factor beta receptor signaling pathway 0 11 2.047790439053915 0.0405805375823447 2.6237864077669903 9.436893203883496 0.1519174108024199 0.5986838967496457 1.9059735511489473 1.2784236570272849 0.7879840609948254 0.2911082215509047 0.2677608232760495 0.1747599807978781 0.3169879022746943 0.6179297811879729 0.5745348929819367 +Ceramide biosynthetic process 7 12 2.047469694962728 0.0406119894320899 4.033980582524272 10.24757281553398 1.048715387316577 0.2344614502118888 2.237979905601341 2.0281678881596505 1.4071730245015133 0.2685344998940062 1.0 1.0 1.0 0.0525727870350727 0.0263404288632578 +Regulation of release of sequestered calcium ion into cytosol 2 11 2.0465456601382326 0.0407027149176113 3.495145631067961 10.606796116504857 -0.1619381357957404 0.5191132619325106 2.1480349403594867 1.8580061416769296 0.939003181999126 0.3010677513139045 0.2677608232760495 0.1747599807978781 0.3169879022746943 0.2450354162713742 0.2968056975451645 +Regulation of calcium ion transport into cytosol 2 11 2.0465456601382326 0.0407027149176113 3.6601941747572817 11.182038834951456 -0.194284247112053 0.5122838466848547 2.173554192187035 2.0044532262828993 0.937125139786062 0.2959244686995 0.3132083871231061 0.2067156970649581 0.3684815592825167 0.3174825468726979 0.4048893372814988 +Regulation of mitochondrion organization 17 47 2.043293628895649 0.0410233799132664 12.08980582524272 45.08252427184466 0.8217268052205459 0.4563186211764868 4.409741308614158 5.146210353910189 1.120993905462196 0.3778427085178187 0.2204389071221316 1.0 0.2930966068708724 0.0534508338637783 0.0009836317698894 +Regulation of protein dephosphorylation 3 30 2.0334250926399555 0.0420095943639726 5.62621359223301 26.402912621359224 0.2250629807618321 0.6684417685530873 3.402753344471267 3.35920576346508 0.6746964835267337 0.292612066176009 0.4055279685123203 0.2742474624411909 0.4707120164826526 0.2100263434971256 0.3928956555746815 +Endoplasmic reticulum to golgi vesicle mediated transport 14 66 2.031074382999233 0.0422474496402676 17.32766990291262 65.39077669902913 0.808881464821498 0.4942452999677598 7.539018980743236 6.620812461410292 1.284359804176963 0.3933269611423161 0.2321650313936224 0.1090224971962506 0.1010318943027543 0.0614256290122905 0.0004576674664181 +Membrane lipid catabolic process 5 12 2.030323415655904 0.0423236755842886 5.854368932038835 11.361650485436892 0.500872843713425 0.1363587272813367 1.9603237645724247 0.9867004907377388 2.113024793917032 0.2289617793743788 1.0 1.0 0.1774332758731671 0.0119341177484456 0.0002838899775346 +Negative regulation of rna catabolic process 10 34 2.027124389957325 0.0426496931336266 11.186893203883496 32.42718446601942 0.419853700893663 0.5432159718224696 4.924332595678975 2.3133296381008863 1.0980554146273172 0.3596399931743501 1.0 1.0 1.0 0.1668895930314442 9.52776098156119e-05 +Endothelial cell proliferation 8 19 2.0253110601722004 0.0428354335397018 3.737864077669903 17.388349514563107 0.8369436650143091 0.4126693113525184 2.24564806763238 2.518795403681403 0.8441326938580735 0.2996825893791121 0.1142884986871186 0.3024216363859021 0.1579906452537346 0.1017129224833184 0.1454895561901762 +Circulatory system process 16 73 2.0242783380131346 0.0429415211713488 17.152912621359224 72.00970873786407 0.7968086684699157 0.4206667688960129 5.8797345113877215 8.195718922280731 1.282615010632819 0.3676426088525382 0.0431820162237652 0.3335237920762112 0.0091066762050372 0.0714213975624427 0.083947483300893 +Hematopoietic progenitor cell differentiation 3 27 2.023614578944491 0.0430098238036424 7.611650485436893 26.978155339805824 -0.2621345576250463 0.6317672300634838 5.112298154600228 2.839049563229125 0.6687477197144174 0.2809635163187214 0.1247526789056344 0.0546342218360011 0.1717287687817776 0.1176097855682859 0.5229854304103481 +Cell recognition 9 25 2.0233238447504824 0.0430397700581841 5.29126213592233 22.859223300970875 0.9056944851933356 0.3618031966115522 2.859598274322472 2.538937048941188 0.9847101891513528 0.3060121099700091 0.0844831452416039 0.2597451867723493 0.0212914346042941 0.0607417341965242 0.0283917079041131 +Positive regulation of mitochondrial translation 2 8 2.0200560524952222 0.0433775736986732 1.8155339805825244 7.439320388349515 1.1233950947475233 0.2654033071264799 1.4295601388514203 1.5544197944414198 1.0052042080836443 0.2741718924063684 0.1128336603904996 0.0711332726649859 0.1362380906066266 0.005208827916976 0.0339846578092061 +Negative regulation of response to external stimulus 10 51 2.002970597664799 0.0451804444848795 9.381067961165048 47.019417475728154 0.8063071074275461 0.4700507256615295 4.127569023520378 6.3589713134688575 0.9364755672970396 0.3491987458588393 0.1546321566358524 0.204463696732403 0.2311252530092082 0.023795781556892 0.1317006116581635 +Ventricular cardiac muscle tissue development 2 6 2.002950644163148 0.0451825863728563 1.6116504854368932 6.567961165048544 0.3904318214236652 0.4380253997625189 1.2578530769833427 1.487077905666335 0.9457728224791138 0.2556599469035547 0.2255660263240682 0.1457663642848915 0.2685353106225043 0.0419909810254146 0.2040147905672061 +Glutathione metabolic process 3 23 1.9990278559888608 0.045605339985308 5.737864077669903 19.91504854368932 -0.2315144781601271 0.5572250910251842 3.0583680052131608 1.719411376919556 0.902925048098778 0.3068938618813106 0.0329878058874648 0.1624541869963563 0.0474859144951228 0.0109251570181746 0.0968264519151924 +Multi multicellular organism process 9 30 1.997960219122165 0.0457209731179502 5.817961165048544 26.4004854368932 0.4199141861061661 0.4886319217993659 2.805744405393114 2.878999920293513 0.979235550100524 0.3132681877599969 0.1463220365086775 0.3426841548479852 0.049541392930243 0.0172426826928339 0.0027222229885513 +Regulation of systemic arterial blood pressure 2 10 1.9958404416964528 0.045951293226178 1.9514563106796117 7.480582524271845 0.6591644372092078 0.3227631999327531 1.1543807719023411 1.5318976272183211 1.1594175747176596 0.2663405748898474 0.2067556173702101 0.1330370821365251 0.031964215627013 0.0326106125072858 0.1665994534041104 +Negative regulation of cyclin dependent protein serine threonine kinase activity 6 9 1.9927776880519437 0.0462857959966722 2.521844660194174 5.883495145631068 0.0909727643578148 0.5803620880436494 1.6493624820604984 1.765642823470682 0.8450320982652144 0.3034042488599743 1.0 1.0 1.0 0.4732445906533414 0.3649620055651655 +Regulation of mitochondrial gene expression 3 14 1.992711844963236 0.0462930095903968 2.594660194174758 11.4247572815534 0.8803116051858394 0.3443222138925089 2.2226265034531534 1.9350293365530056 0.991093358800792 0.2980671372776958 0.1939653795966551 0.1244478155008913 0.2318581098993339 0.0270423729706739 0.0404595824929281 +Antigen processing and presentation of peptide antigen 3 12 1.9909432325978784 0.046487128538496 4.050970873786408 11.99271844660194 0.9279525789651738 0.3302951212632576 1.9792182503824105 1.8740552023113428 1.0022067378347963 0.2823588878170496 0.2378608432520957 0.1541506060207377 0.0428134756181982 0.0489147892655661 0.0821355875685036 +Glycosylation 21 50 1.9873795920558592 0.0468803474860743 13.33495145631068 45.42718446601942 0.831363055351092 0.4028474919440285 5.5712021107485015 7.578523489860055 1.3433056638769032 0.3649215649501745 0.3697559816775991 0.5519068441575339 0.4686849108889498 0.1003048311830493 0.0271169751471381 +Lipoprotein catabolic process 2 6 1.9821770042564757 0.047459433458223 1.529126213592233 5.211165048543689 0.7074087979902727 0.279320898549559 1.1111204061152251 0.9407555329409328 1.2623530327786678 0.2599848817817885 0.1128336603904996 0.0711332726649859 0.0090253131212995 0.005208827916976 0.0339846578092061 +Negative regulation of ryanodine sensitive calcium release channel activity 1 5 1.977560904463496 0.0479782633813878 1.444174757281553 4.065533980582524 0.3321131309656542 0.4579950429194244 1.118810936310271 0.8232521681359034 1.085014771474357 0.320683899890456 0.0618356471863385 0.0385773062479974 0.075113296023457 0.014977467250991 0.0548161530025184 +Positive regulation of sequestering of calcium ion 1 5 1.977560904463496 0.0479782633813878 1.444174757281553 4.065533980582524 0.3321131309656542 0.4579950429194244 1.118810936310271 0.8232521681359034 1.085014771474357 0.320683899890456 0.0618356471863385 0.0385773062479974 0.075113296023457 0.014977467250991 0.0548161530025184 +Negative regulation of calcium ion transport into cytosol 1 5 1.977560904463496 0.0479782633813878 1.483009708737864 4.230582524271845 0.3306337803947523 0.4637675394464941 1.1222388639977254 0.9361855318182722 1.0781916094045627 0.3229994495869239 0.0840370854942358 0.0526645480715484 0.1018169846714528 0.0280420066437826 0.0978216105640502 +Positive regulation of monooxygenase activity 2 7 1.9774736633549304 0.0479881146180083 1.6844660194174756 5.415048543689321 1.0370130759472405 0.2898065983925483 1.0180179945339054 0.878583782950111 0.884976405150879 0.2417237008540366 0.0061207505190791 0.0023758658868836 0.0090253131212995 0.005208827916976 0.0339846578092061 +Rna stabilization 8 28 1.974453760536862 0.0483301702484539 9.359223300970871 27.37621359223301 0.4792302048577673 0.5262457931829767 4.411160534464403 1.6856669427134765 1.0994939820726763 0.3614208213771557 1.0 1.0 1.0 0.1161428196700428 0.000525961744528 +Sterol homeostasis 1 14 1.9689914130281607 0.0489540771623222 3.2597087378640777 11.594660194174756 0.7425754872590924 0.2773502445350785 1.6018884221780605 1.6170423171351411 1.3033948892752858 0.2615762483252933 0.036438538257684 0.0148056693212618 0.0523352985295366 0.2359805031570881 0.2832795756669947 +Amide transport 11 41 1.9688973327988424 0.0489648819095775 9.512135922330096 37.99757281553398 0.8625203235532012 0.4243895840783888 3.9342099663331425 4.541875701235624 0.963016155404646 0.3369249994514658 0.2970328396287751 1.0 0.148051344240397 0.1171170078758993 0.1328139868440714 diff --git a/msigdb_gobp/metrics.json b/msigdb_gobp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..d253645bb6e57b1a0d75f495cab9c7ae807af8e4 --- /dev/null +++ b/msigdb_gobp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3329, + "annotations_size": 6494, + "title": "Average number of proteins per term", + "value": 20.35833076686172 +} \ No newline at end of file diff --git a/msigdb_gobp/paths.json b/msigdb_gobp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..15695957713a4cf35fbde37d003af3896e229544 --- /dev/null +++ b/msigdb_gobp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gobp/fragment/C342/C342_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gobp/result.tsv b/msigdb_gobp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..8627401009784fd03c50af5fdd1168a82a5a8e9a --- /dev/null +++ b/msigdb_gobp/result.tsv @@ -0,0 +1,1832 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mitochondrial transmembrane transport 0.6827310815350366 3.602729484876046 0.0003148931880856 0.870650650085635 0.3094913707828747 51 P21796,Q9BSK2,Q99595,Q9H2D1,Q9Y619,O95831,O43772,P23786,Q8N4Q1,P00846,O95563 11 +Membrane lipid metabolic process 0.6937515346513798 3.329388212171079 0.0008703699547558 0.9964987795080364 0.3094913707828747 40 P50897,Q16739,P17900,Q96G23,Q8NBX0,Q99805,Q9P035,Q9Y2B2,P07602,Q06136,P30153,Q8NCC3,Q9NZ01,O95470,Q13510,O15270,P04062 17 +Secondary alcohol metabolic process 0.6625714733042939 3.281940155885195 0.0010309548259599 0.9987672084712232 0.3094913707828747 44 Q16850,Q15125,P37268,P48449,Q15392,Q15800,Q8WTV0,O75874,P48735,Q14739,P04062 11 +Anion transport 0.6043627736867663 3.2804322834858444 0.0010364814270618 0.9988107126672982 0.3094913707828747 64 P14174,Q9UBX3,P12235,P07602,Q96S66,P53985,Q9Y619,P41440,P08183,P21796,Q96NB2,P45880,Q6NUK1,Q15041,Q9H2D1,Q13546,P30536,O95563,Q96QD8,Q02978,Q9H813,Q9Y4C2,Q9UHG3,P04083,P0CG08 25 +Organic acid transmembrane transport 0.7507143578179344 3.2647491050434834 0.0010956107647461 0.9991902595015516 0.3094913707828747 28 P53985,Q15041,Q9H2D1,Q9Y619,Q9UBX3,Q96QD8,Q02978,O43772,P23786,P31749,P41440,O95563 12 +Sphingolipid metabolic process 0.7346360464618971 3.2602945527920366 0.0011129656512396 0.9992766547753186 0.3094913707828747 31 P50897,Q16739,P17900,Q96G23,Q99805,Q9P035,P07602,Q06136,P30153,Q8NCC3,Q9NZ01,O95470,Q13510,O15270,P04062 15 +Peptidyl proline modification 0.7141358364604579 3.2356708284224487 0.0012135724425852 0.9996239262762696 0.3094913707828747 34 P62942,P26885,Q32P28,Q9BV86,Q9Y680,P13674,Q02790,Q96AY3,Q9NWM8,Q13451 10 +Mitochondrial transport 0.5663127328343762 3.1772109601288436 0.0014869882872672 0.9999364503212472 0.3094913707828747 85 Q9UBX3,P12235,Q9NS69,P00846,Q99595,O43772,Q8N4Q1,P45880,Q15070,P23786,P30536,P49257,Q8N4H5,O95831,O75964,O95429,O14925,P55786,O14737,O95140,Q5JRX3 21 +Organic acid transport 0.6474308103336688 3.173144124460666 0.0015079764624428 0.9999445589483296 0.3094913707828747 44 P14174,P53985,Q15041,Q9H2D1,Q9Y619,Q9UBX3,Q96QD8,Q02978,O43772,P23786,P31749,P04083,Q6P4A7,P41440,Q01469,O95563 16 +Anion transmembrane transport 0.676065005584536 3.1007810198932204 0.0019301096981056 0.999996441758486 0.3094913707828747 37 Q9UJS0,P08183,P53985,P21796,Q96NB2,P45880,Q15041,Q9Y619,Q9UBX3,Q9H2D1,P12235,Q13546,Q02978,Q9Y4C2,Q9UHG3,P41440,O95563 17 +Alcohol biosynthetic process 0.6643263189694172 3.091310467309319 0.0019927515518238 0.9999976328876437 0.3094913707828747 39 Q16850,Q15125,P37268,P48449,P00374,Q15392,Q15800,P35270,Q14739,O15270,P04062 11 +Regulation of blood pressure 0.7640480259338011 3.006301568920256 0.0026444658830222 0.9999999659660906 0.3094913707828747 20 Q9UIQ6,Q9HB40,P42785,P42892,P09601,Q9NZ08 6 +Protein peptidyl prolyl isomerization 0.7214087670249181 2.986752683730093 0.0028195771927146 0.9999999891184442 0.3094913707828747 25 P62942,P26885,Q9Y680,Q02790,Q96AY3,Q9NWM8 6 +Sterol biosynthetic process 0.7265868303632927 2.969015198494787 0.0029875581945808 0.9999999963562114 0.3094913707828747 24 Q16850,Q15125,P37268,P48449,Q15392,Q15800,Q14739 7 +Organic anion transport 0.6188403957276629 2.844344734270779 0.0044502869578209 0.9999999999997364 0.3094913707828747 41 P14174,Q15041,Q9H2D1,Q9Y619,Q9UBX3,Q96QD8,P12235,Q02978,P07602,P04083,P41440,O95563 12 +Ceramide metabolic process 0.7249796485481977 2.8297060673412635 0.0046590785831106 0.9999999999999324 0.3094913707828747 21 Q16739,P17900,Q96G23,Q99805,P30153,Q8NCC3,O95470,Q13510,O15270,P04062 10 +Membrane lipid biosynthetic process 0.6918408055458817 2.810745568181792 0.0049426854689356 0.9999999999999892 0.3094913707828747 25 Q16739,Q96G23,Q8NBX0,Q99805,Q9P035,Q06136,O95470,Q13510,O15270,P04062 10 +Sphingolipid biosynthetic process 0.7442781300632948 2.778440156613806 0.0054620573382377 0.9999999999999996 0.3094913707828747 18 Q16739,P04062,Q96G23,Q9P035,Q06136,O95470,O15270,Q99805 8 +Protein targeting to mitochondrion 0.5744040041977386 2.7455017332029503 0.0060418448328742 1.0 0.3094913707828747 49 Q99595,O95831,Q9NS69,O95429,Q8N4Q1,O14925,P30536,P55786,O95140,Q5JRX3,P49257,Q8N4H5 12 +Carboxylic acid transport 0.6418894827227919 2.7322302805368777 0.0062907155238873 1.0 0.3094913707828747 33 P14174,Q15041,Q9H2D1,Q9Y619,Q9UBX3,Q96QD8,Q02978,P07602,P04083,P41440,O95563 11 +Negative regulation of transmembrane transport 0.6826602073079422 2.7097645505410006 0.0067330985836135 1.0 0.3094913707828747 24 P62942,P21796,P78417,P31749,Q01469 5 +Sterol metabolic process 0.6086573683162225 2.700384141458883 0.0069259455305945 1.0 0.3094913707828747 39 Q16850,Q15125,P37268,P48449,Q15392,Q15800,Q8WTV0,Q14739,P04062 9 +Organic hydroxy compound biosynthetic process 0.5547164599992057 2.6882167176808185 0.0071834758175537 1.0 0.3094913707828747 56 Q16850,Q15125,P37268,P48449,P00374,Q15392,Q15800,P35270,Q14739,O15270,P04062 11 +Organophosphate ester transport 0.6710823776998893 2.6848201279232757 0.0072568849400647 1.0 0.3094913707828747 25 Q9BSK2,Q9H2D1,Q8WTV0,P41440,Q14108 5 +Protein localization to mitochondrion 0.5352428491422837 2.6808570238798604 0.0073433883762297 1.0 0.3094913707828747 64 Q9NS69,Q8WWC4,Q99595,Q8N4Q1,Q15070,P11233,P31749,P30536,P52789,P49257,Q8N4H5,O95831,O95429,O14925,P55786,O14737,Q5JRX3,O95140,Q9Y6C9 19 +Cellular modified amino acid metabolic process 0.5481069306490821 2.667864270729387 0.0076335089230199 1.0 0.3094913707828747 58 O15217,P78417,Q9UJ14,Q9H2D1,P00374,P23786,O75874,Q9UHG3,Q8NCC3,P41440,O60725,Q9NVH6,Q8N2K0 13 +Protein transmembrane transport 0.6741146798891793 2.658335493729344 0.007852767743447 1.0 0.3094913707828747 24 Q99595,O95831,Q15629,Q9NS69,Q8N4Q1 5 +Alcohol metabolic process 0.5119742622307388 2.632208077756613 0.0084831890117225 1.0 0.3094913707828747 88 Q16850,Q15125,P37268,P48449,P00374,Q15392,O75874,Q8WTV0,Q15800,P48735,P35270,Q14739,O15270,P04062 14 +Amyloid precursor protein catabolic process 0.6903694678585264 2.6318633531991487 0.0084918009411683 1.0 0.3094913707828747 21 P62942,Q15392,Q16799 3 +Steroid biosynthetic process 0.5546067101278908 2.5541664523732712 0.0106442358091496 1.0 0.3405106765744717 46 Q16850,Q15125,P37268,P48449,Q15392,Q15800,P30536,Q14739 8 +Negative regulation of ion transmembrane transport 0.6883017648011346 2.5482196869645235 0.010827426282002 1.0 0.3446730699770657 19 P62942,P21796 2 +Amyloid precursor protein metabolic process 0.6507076790457846 2.515751264467594 0.0118778977441256 1.0 0.3703563445219808 24 P62942,Q15392,Q16799 3 +Mitochondrial respiratory chain complex assembly 0.5595281742220524 2.5120725850506433 0.0120024398896518 1.0 0.3703563445219808 44 Q9Y512,Q9BSK2,Q9H061,O43676,Q9Y2R0,Q15070,O95831,Q9Y6M9,Q96CU9,Q69YU5,O75306,Q8N4Q1,O75438,O95168,Q86Y39,Q6DKK2,O75880 17 +Steroid metabolic process 0.5000014881915864 2.5061745278676058 0.0122045361453193 1.0 0.3703563445219808 70 Q16850,Q15125,P37268,P48449,P38435,Q15392,Q15800,Q8WTV0,P30536,Q14739,O95470,P04062 12 +Vacuolar acidification 0.8404784145681305 2.504498597399426 0.0122625091469052 1.0 0.3703848111628047 9 P50897,Q93050,Q9Y487,O75503 4 +Negative regulation of calcium ion transmembrane transport 0.8294900332137546 2.456420155551055 0.0140328982124566 1.0 0.3813928335948476 9 P21796,P62942 2 +Carbohydrate derivative transport 0.7269088329449614 2.4110542762417775 0.0159064810956646 1.0 0.3972949547509462 14 P07602,Q8WTV0,P41440 3 +Regulation of phospholipid metabolic process 0.7775999714753529 2.4087639541536587 0.0160066468605921 1.0 0.3982649988991782 12 Q8WTV0 1 +Retrograde vesicle mediated transport golgi to endoplasmic reticulum 0.5971129469685358 2.400219826264332 0.0163852286341841 1.0 0.4030517982969382 32 Q9Y282,Q9P2W9,P18085,P42858,O43731,Q96JB2,P24390 7 +Regulation of calcium ion transmembrane transport 0.653578328283297 2.3811747525027447 0.0172575229603821 1.0 0.4090158908931457 20 P62942,P21796,P78417,P42858,Q00535,Q06787 6 +Protein maturation 0.4747896669514972 2.3732501412294273 0.0176323182024706 1.0 0.4159306614603145 74 P62942,O75844,Q5VZE5,Q9BU23,Q9BXS4,Q15392,Q5JRX3,Q8N4Q1,P42892,O75503,Q86UY6,Q9UMY4,O75976 13 +Ph reduction 0.7437373764400336 2.3657371410561225 0.017994215186849 1.0 0.4203396885733736 13 P50897,Q93050,Q9Y487,O75503 4 +Cytosolic calcium ion transport 0.6318960355183963 2.3593444040003835 0.0183072563795065 1.0 0.4222220650924676 23 P62942,P21796,P78417,P42858,Q8WWC4,P16615 6 +Nucleotide transmembrane transport 0.8059825901347809 2.3525648377611343 0.0186444389974527 1.0 0.4222220650924676 9 Q9BSK2,Q9H2D1,P41440 3 +Transmembrane transport 0.5295517776717413 2.3102478327055502 0.0208744372554661 1.0 0.4430019461993364 211 P62942,O75844,Q9UBX3,Q99523,P12235,Q9HD20,Q8WTV0,Q9NS69,Q9NQ11,Q8WWC4,P00846,Q70HW3,Q06787,Q99595,Q9Y619,P42858,O43772,Q9UDW1,Q6NT16,Q8N4Q1,P41440,P04062,P21796,Q9BSK2,P45880,Q8IXU6,Q9H2D1,P78417,Q15041,Q15629,P23786,P31749,Q9HC07,O95563,P20674,O95831,O75964,Q02978,P38435,Q96QD8,Q03518,Q9UHG3,O14925,Q6P4A7,Q01469 45 +Negative regulation of calcium ion transport 0.7780403126236778 2.299660579575879 0.0214674571012019 1.0 0.4462148739068655 11 P21796,P62942 2 +Regulation of amyloid precursor protein catabolic process 0.6577790828852661 2.2985789348943393 0.0215288608594335 1.0 0.4462148739068655 18 P62942,Q16799 2 +Inorganic anion transport 0.627858406281861 2.2969297194657976 0.0216227792870575 1.0 0.4462148739068655 22 P21796,P08183,P51790,P45880,Q9UBX3,Q02978,Q9H813,P54105,Q9UHG3,P0CG08,P30536,Q96S66 12 +Terpenoid metabolic process 0.6698120329081061 2.296720439296677 0.021634722698814 1.0 0.4462148739068655 17 P48449,Q9BY49,Q9HB40,P37268 4 +Cytochrome complex assembly 0.7279974267397085 2.2874888012067025 0.0221673083560607 1.0 0.4462148739068655 13 Q9BSK2,P53701,Q15070,Q9Y2R0,Q69YU5,Q6DKK2 6 +Lipoprotein metabolic process 0.6351650751914892 2.272042678232568 0.0230839327347147 1.0 0.4524755618890896 20 P50897,Q9NUJ1,Q8N2K0,P04062 4 +Regulation of cytosolic calcium ion concentration 0.617402335935641 2.26942896974868 0.0232422521496944 1.0 0.4524755618890896 23 P62942,P78417,Q9Y639 3 +Regulation of ph 0.6232503936795063 2.26866100550326 0.0232889486558858 1.0 0.4524755618890896 22 P50897,Q8N511,Q93050,Q9Y487,O75503,Q9HC07 6 +Regulation of cellular ph 0.6232503936795063 2.26866100550326 0.0232889486558858 1.0 0.4524755618890896 22 P50897,Q8N511,Q93050,Q9Y487,O75503,Q9HC07 6 +Long chain fatty acid transport 0.720986737342536 2.252388912001149 0.0242977058079871 1.0 0.4627252243902309 13 P14174,P23786,O43772,P31749,P04083 5 +Negative regulation of mrna catabolic process 0.5942567198177087 2.242944818925059 0.0249003731002557 1.0 0.4633621607395184 26 Q92804,P98175,Q14011,P35637,P16989,Q14103,Q99729,P67809,O60506 9 +Negative regulation of transporter activity 0.6716945276353079 2.241334460127856 0.0250044183907107 1.0 0.4633621607395184 16 P62942 1 +Chaperone mediated protein folding 0.5339548780672742 2.2388551691345735 0.02516534126293 1.0 0.4633621607395184 42 P62942,P26885,Q32P28,Q02790,O75718,Q13451,Q9H2J4 7 +Regulation of pattern recognition receptor signaling pathway 0.6124777267149678 2.238652130436122 0.0251785594844473 1.0 0.4633621607395184 23 Q9NPR9,Q9NUD5,P41440 3 +Regulation of lysosomal lumen ph 0.8539791578627938 2.2362383730956132 0.0253361608539972 1.0 0.4633621607395184 7 P50897,Q9HC07,O75503 3 +Intracellular protein transmembrane transport 0.6229664833521682 2.231899425803427 0.0256216108569082 1.0 0.4633621607395184 21 O95831,Q8N4Q1,Q99595,Q15629 4 +Nucleotide transport 0.7627897676924462 2.229086283652175 0.0258081643662897 1.0 0.4633621607395184 11 Q9BSK2,Q9H2D1,P41440 3 +Dicarboxylic acid transport 0.6914994440309905 2.227140354095469 0.0259378949484512 1.0 0.4633621607395184 14 Q02978,Q9H2D1,Q15041,P41440 4 +Vitamin transmembrane transport 0.931107099879668 2.2261195499940523 0.0260061747695599 1.0 0.4633621607395184 5 P04062,Q9H2D1,Q8WTV0,P41440 4 +Vitamin transport 0.931107099879668 2.2261195499940523 0.0260061747695599 1.0 0.4633621607395184 5 P04062,Q9H2D1,Q8WTV0,P41440 4 +Membrane protein proteolysis 0.7139406831961068 2.2169575220247673 0.0266259943924491 1.0 0.4633621607395184 13 Q16740,Q9NZ08,Q8TCT8 3 +Alternative mrna splicing via spliceosome 0.5222026339561399 2.2148864563076147 0.0267678589536592 1.0 0.4633621607395184 44 Q13242,O60828,Q06787,Q15007,Q9BWF3,P98175,Q92841,Q8NDT2,Q8IY67,O60341,Q9UHX1,Q13247,P51114,O75525,Q07955,P62995,P09651,P51116,O95391,P38159 20 +Cardiac ventricle development 0.6882656714927756 2.2101332269190395 0.0270959174555505 1.0 0.4633621607395184 14 P62942,O75844 2 +Peptide catabolic process 0.7585064278496637 2.2091525627772852 0.0271640311291012 1.0 0.4633621607395184 11 P42892,Q9UJ14,Q9UIQ6,Q9NZ08 4 +Regulation of calcium ion transmembrane transporter activity 0.6761786309397938 2.204013525884431 0.0275233928660596 1.0 0.4633621607395184 15 P62942,P78417,P42858,Q00535,Q06787 5 +Folic acid metabolic process 0.8450268510019343 2.199342858768758 0.0278535523772709 1.0 0.4633621607395184 7 P00374,P41440,Q9H2D1,P34896 4 +Mitochondrial membrane organization 0.5077901935923076 2.1975584205235315 0.0279805890091133 1.0 0.4633621607395184 49 Q5XKP0,P45880,Q15070,Q9BUR5,P12235,Q9NX63,Q9NS69,O14737,Q9H3K2,P52789,Q8WWC4,O95140,Q9Y512,O60313 14 +Protein transmembrane import into intracellular organelle 0.7100049711518925 2.1970990654877034 0.0280133718517503 1.0 0.4633621607395184 13 O95831,Q8N4Q1,Q99595 3 +Calcium ion transport into cytosol 0.6847813170226105 2.191768415169717 0.0283962328387867 1.0 0.4633621607395184 14 P62942,P78417 2 +Negative regulation of ion transport 0.6049754061898673 2.191544157501685 0.0284124379339831 1.0 0.4633621607395184 23 P62942,P21796 2 +Protein maturation by protein folding 0.8424890395876292 2.1888541988802936 0.0286074389291837 1.0 0.4633621607395184 7 P62942 1 +Positive regulation of i kappab kinase nf kappab signaling 0.5395805949765243 2.188225405077458 0.0286531874227145 1.0 0.4633621607395184 39 P62942,P19474,P09601 3 +Protein hydroxylation 0.6603946734433813 2.1790946306531183 0.0293246390609858 1.0 0.4633621607395184 16 Q32P28,Q92791,P13674,Q96AY3,O15460 5 +Fatty acid transmembrane transport 0.886927209257135 2.174133074367442 0.0296951427077099 1.0 0.463558309480452 6 P23786,O43772 2 +Negative regulation of cation channel activity 0.791032677110246 2.1720535616719694 0.029851623128889 1.0 0.4638316054006501 8 P62942 1 +Macromolecule depalmitoylation 0.8863291442724115 2.1717872517021495 0.0298717136971113 1.0 0.4638316054006501 6 P50897,Q9NUJ1,Q8N2K0 3 +Negative regulation of ion transmembrane transporter activity 0.6763409853290407 2.147110892608151 0.0317844543317027 1.0 0.4712517041782593 14 P62942 1 +Heart morphogenesis 0.5767205357160059 2.145907762193283 0.0318803383997086 1.0 0.4715966231610654 27 P62942,O14641,O75844,P09493,Q15363 5 +Regulation of cation channel activity 0.6280647770880085 2.1268898427064027 0.0334292370069537 1.0 0.4813513639094408 18 P62942,P78417,P42858,Q00535,Q06787 5 +Calcium ion transmembrane transport 0.5341572963943642 2.118484088088094 0.0341340910962264 1.0 0.4874036933124115 38 P62942,P21796,P78417,P42858,Q00535,Q8WWC4,P16615,Q9HC07,Q06787 9 +Regulation of toll like receptor signaling pathway 0.7391162077175344 2.118298667677398 0.0341497814070137 1.0 0.4874036933124115 11 Q9NPR9 1 +Fatty acid transport 0.6488603962575035 2.115074265062486 0.0344236182137154 1.0 0.4888073187042084 16 P14174,P23786,O43772,P31749,P04083 5 +Protein quality control for misfolded or incompletely synthesized proteins 0.7162846705026951 2.11374416575529 0.0345371240916545 1.0 0.4888073187042084 12 Q16740,P46379,Q9BUN8 3 +Cellular hormone metabolic process 0.6368663438778865 2.110763943767618 0.0347926067162172 1.0 0.4888073187042084 17 P42892,O95470,Q9HB40 3 +Negative regulation of mrna metabolic process 0.4980915749653185 2.097562589879083 0.0359438027147569 1.0 0.4923280511371868 47 Q5VTR2,Q13242,P11940,P16989,Q14103,Q06787,O60506,P61978,P98175,Q99729,Q13247,P67809,P22626,Q14011,Q16539,Q13148,P26368,Q07021,Q92804,P38159,P35637 21 +Dna replication checkpoint signaling 0.8200825657798133 2.095685050614709 0.0361101388614391 1.0 0.4923280511371868 7 Q9Y619 1 +Neuron apoptotic process 0.4951318000185846 2.089399193129314 0.0366718038067053 1.0 0.4971747263481093 49 P50897,Q15058,Q99720,Q969N2,Q9NR28,P51858,O95831,Q01105,O95630,P07196,P09601,O76024,Q00535,P49327,Q04446,P42574,Q96A26,P04062 18 +Pteridine containing compound metabolic process 0.6214572944287018 2.088222588157487 0.0367777606424184 1.0 0.4972237840912593 18 Q9H2D1,P00374,P34896,P35270,P41440 5 +Sequestering of calcium ion 0.6328244898805765 2.0876595555158426 0.0368285556125493 1.0 0.4972237840912593 17 P62942,P78417 2 +Cellular monovalent inorganic cation homeostasis 0.5705895824537872 2.0861848034447057 0.0369618862483962 1.0 0.4979885670064009 26 P50897,Q8N511,Q93050,Q9Y487,O75503,Q9HC07 6 +Lysosomal lumen acidification 0.8900365842666795 2.0669491474188497 0.0387389459561822 1.0 0.5082801599743932 5 P50897,O75503 2 +Isoprenoid metabolic process 0.5907482301884631 2.066480605086002 0.0387831218805569 1.0 0.5082801599743932 22 P48449,Q9BY49,Q9HB40,P37268 4 +Metal ion homeostasis 0.447594243228204 2.0657325519177303 0.0388537398461816 1.0 0.5082801599743932 77 P62942,P30519,Q9HD20,Q9NQ11,Q9Y6N1,Q9Y487,Q8WWC4,P42858,O15164,Q9Y5X3,P09601,O75880,Q8N511,P78417,Q9HC07,Q9Y639,P02786,Q00535,P16615 19 +Blood vessel endothelial cell migration 0.5791015257336933 2.063356405470852 0.0390787786338653 1.0 0.5085723215397223 24 P42785,P09601,Q8WTV0 3 +Protein depalmitoylation 0.8885768555307242 2.061242497052852 0.0392799110712491 1.0 0.5087814390478216 5 Q9NUJ1,Q8N2K0 2 +Positive regulation of protein binding 0.5838821520750116 2.057656036210714 0.0396231634246988 1.0 0.5114001784196274 23 P62942,P41440 2 +Glycerophospholipid catabolic process 0.7398774880355048 2.0530824790607225 0.0400645789279137 1.0 0.5120962809353395 9 Q8NCC3,Q8WTV0 2 +Neutral lipid biosynthetic process 0.8098786641083553 2.052920921005203 0.0400802476298534 1.0 0.5120962809353395 7 Q8WTV0 1 +Ceramide biosynthetic process 0.7028130187613768 2.0474696949627273 0.0406119894320899 1.0 0.5120962809353395 12 Q16739,Q9NRA0,Q96G23,O15269,Q13510,O15270,P04062 7 +Regulation of release of sequestered calcium ion into cytosol 0.7239528408377573 2.0465456601382326 0.0407027149176113 1.0 0.5120962809353395 11 P62942,P78417 2 +Regulation of calcium ion transport into cytosol 0.7239528408377573 2.0465456601382326 0.0407027149176113 1.0 0.5120962809353395 11 P62942,P78417 2 +Regulation of mitochondrion organization 0.4917132952820967 2.043293628895649 0.0410233799132664 1.0 0.5120962809353395 47 P21796,Q9H4A6,P02786,P42858,O75832,P12235,P11233,Q9NQ11,P31749,Q9Y6C9,O14737,P30536,Q9H3K2,Q96A26,P10909,Q9NUQ9,O60313 17 +Regulation of protein dephosphorylation 0.5513041919714468 2.0334250926399555 0.0420095943639726 1.0 0.5120962809353395 30 P62942,Q86XL3,P04062 3 +Endoplasmic reticulum to golgi vesicle mediated transport 0.4611975963870653 2.031074382999233 0.0422474496402676 1.0 0.5120962809353395 66 Q96JB2,Q9Y282,O15027,Q9BVK6,P18085,Q96PC5,Q9P2W9,O43731,Q15363,Q92734,P24390,Q8IUR0,Q9Y6Y8,P49257 14 +Membrane lipid catabolic process 0.6993449935654524 2.0303234156559036 0.0423236755842886 1.0 0.5120962809353395 12 P50897,P17900,O95470,Q13510,P04062 5 +Negative regulation of rna catabolic process 0.537005478680454 2.027124389957325 0.0426496931336266 1.0 0.5120962809353395 34 Q92804,P98175,Q14011,P35637,P16989,Q14103,P67809,Q99729,Q06787,O60506 10 +Endothelial cell proliferation 0.5992341575640977 2.0253110601722004 0.0428354335397018 1.0 0.5120962809353395 19 P78536,P57105,O94788,Q8WTV0,P31749,P09601,Q9H2J4,O75340 8 +Circulatory system process 0.4437452546462656 2.0242783380131346 0.0429415211713488 1.0 0.5120962809353395 73 P08183,P53985,P78417,O75844,P02786,Q96QD8,Q9UIQ6,Q9HB40,P09493,P42785,Q9Y5X3,P42892,P09601,Q9NZ08,P41440,Q01469 16 +Hematopoietic progenitor cell differentiation 0.5586151420192468 2.023614578944491 0.0430098238036424 1.0 0.5120962809353395 27 Q96PZ0,Q9NPH0,Q9Y5A9 3 +Cell recognition 0.5671817503284191 2.0233238447504824 0.0430397700581841 1.0 0.5120962809353395 25 P35613,P45880,Q5KU26,Q92614,Q14157,Q8WTV0,P48643,P42574,Q9Y639 9 +Positive regulation of mitochondrial translation 0.7567003465481574 2.0200560524952222 0.0433775736986732 1.0 0.5140400795605548 8 Q567V2,Q9Y2R0 2 +Negative regulation of response to external stimulus 0.482983354994799 2.002970597664799 0.0451804444848795 1.0 0.5253101821850946 51 P14174,P19474,P28070,Q96G23,Q9UMX5,P46108,P80303,O43657,Q9Y5A9,P04062 10 +Ventricular cardiac muscle tissue development 0.8436958954728545 2.002950644163148 0.0451825863728563 1.0 0.5253101821850946 6 P62942,O75844 2 +Glutathione metabolic process 0.574749943834546 1.9990278559888612 0.045605339985308 1.0 0.5253101821850946 23 O15217,Q9UJ14,O75874 3 +Multi multicellular organism process 0.5462577322204367 1.997960219122165 0.0457209731179502 1.0 0.5253101821850946 30 Q96QD8,Q8IZL8,Q9UIQ6,P31749,P07858,Q02790,Q15363,P41440,P35613 9 +Regulation of systemic arterial blood pressure 0.7204878319505532 1.9958404416964528 0.045951293226178 1.0 0.5253656658640853 10 P42785,P42892 2 +Negative regulation of cyclin dependent protein serine threonine kinase activity 0.7268537501474971 1.9927776880519432 0.0462857959966722 1.0 0.5274154461053282 9 O95373,P53350,Q96SZ6,O94992,P42771,P42574 6 +Regulation of mitochondrial gene expression 0.6475062461653043 1.992711844963236 0.0462930095903968 1.0 0.5274154461053282 14 Q9NYY8,Q567V2,Q9Y2R0 3 +Antigen processing and presentation of peptide antigen 0.691406421253711 1.9909432325978784 0.046487128538496 1.0 0.5282115358884368 12 Q9UIQ6,Q03518,Q9NZ08 3 +Glycosylation 0.4823058387974235 1.9873795920558592 0.0468803474860743 1.0 0.529462567955769 50 Q86YN1,Q9BXS4,Q14165,O15118,P15291,Q6ZXV5,O43505,O60502,P26572,O75503,O43909,Q13724,P04062,Q9Y5P6,Q06210,Q10471,O75340,Q9HC07,Q9BT22,Q96JB2,O60476 21 +Lipoprotein catabolic process 0.8385046751653072 1.9821770042564757 0.047459433458223 1.0 0.5298600244076586 6 Q9NUJ1,Q8N2K0 2 +Negative regulation of ryanodine sensitive calcium release channel activity 0.8672684006227518 1.9775609044634956 0.0479782633813878 1.0 0.5305421300566469 5 P62942 1 +Positive regulation of sequestering of calcium ion 0.8672684006227518 1.9775609044634956 0.0479782633813878 1.0 0.5305421300566469 5 P62942 1 +Negative regulation of calcium ion transport into cytosol 0.8672684006227518 1.9775609044634956 0.0479782633813878 1.0 0.5305421300566469 5 P62942 1 +Positive regulation of monooxygenase activity 0.7919960119774252 1.9774736633549304 0.0479881146180083 1.0 0.5305421300566469 7 P00374,Q8WTV0 2 +Rna stabilization 0.5487068138434791 1.974453760536862 0.0483301702484539 1.0 0.5319595349041698 28 Q92804,P98175,Q14011,P35637,P16989,Q14103,P67809,O60506 8 +Sterol homeostasis 0.6431227601971257 1.9689914130281607 0.0489540771623222 1.0 0.5370554080096277 14 Q8WTV0 1 +Amide transport 0.5040131589383091 1.9688973327988424 0.0489648819095775 1.0 0.5370554080096277 41 Q8N183,P08183,P53985,Q9H2D1,Q16836,Q03518,P07602,P04083,Q8N5M9,P41440,O95563 11 +Diol metabolic process 0.7189499690093573 1.955972070384162 0.0504684443277145 1.0 0.5417224420895512 9 P00374,P35270,P04062 3 +Diol biosynthetic process 0.7189499690093573 1.955972070384162 0.0504684443277145 1.0 0.5417224420895512 9 P00374,P35270,P04062 3 +Regulation of nitric oxide synthase activity 0.7408160218628448 1.9488106090097208 0.0513180463460243 1.0 0.549027006542145 8 P00374,Q8WTV0 2 +Maintenance of location in cell 0.4805642906153852 1.947633122437296 0.0514588775463189 1.0 0.5496282085292685 47 P62942,P78417,P31749,O43731,P30536,P24390 6 +Antigen processing and presentation of peptide antigen via mhc class i 0.7024661990926244 1.943814447765456 0.0519178308697041 1.0 0.5530126880694739 11 Q9UIQ6,Q03518,Q9NZ08 3 +Regulation of biological process involved in symbiotic interaction 0.7162964866204442 1.943580460207132 0.0519460640163811 1.0 0.5530126880694739 9 P19474 1 +Mitochondrion localization 0.5810626139146537 1.9427963887689192 0.0520407644167837 1.0 0.553114114766929 20 Q6PJG6,Q9BUK6,P07196,O95140,O60313,O75153 6 +Positive regulation of nitric oxide synthase activity 0.8570703060024245 1.9372642941472609 0.052713044541369 1.0 0.5574827570486678 5 P00374,Q8WTV0 2 +Collagen fibril organization 0.7822464368391716 1.9360732076534797 0.0528587354151433 1.0 0.5574827570486678 7 P13674,Q96AY3,Q92791 3 +Regulation of neurotransmitter transport 0.6353854044819192 1.9269626704135765 0.0539842822568403 1.0 0.5601697777827143 14 P35080,Q4J6C6,Q00535,Q9P253,P41440,P16615,P0DP25,Q06787 8 +Transition metal ion transport 0.6339345273258562 1.9190590007522204 0.0549768673821919 1.0 0.5614123096381495 14 O15173,Q02790,Q9HD20 3 +Glycerolipid biosynthetic process 0.4770587276720753 1.9106830649093685 0.056045322425549 1.0 0.5677732512700415 46 Q9NPH0,Q9Y2B2,Q9UBF8,Q8WTV0,Q8NCC3,Q01469,P42356,P35790,O95674 9 +Antigen processing and presentation of exogenous peptide antigen 0.8503520996201059 1.9106323602993065 0.0560518427167324 1.0 0.5677732512700415 5 Q9UIQ6 1 +Cardiac ventricle morphogenesis 0.8502593166323577 1.9102640834753009 0.0560992197391763 1.0 0.5677732512700415 5 P62942 1 +De novo protein folding 0.5643575465567481 1.8986978803840289 0.0576042104171239 1.0 0.5714832297891764 22 P62942 1 +Tetrapyrrole catabolic process 0.9437326242322768 1.896635629228859 0.0578760448045296 1.0 0.5714832297891764 4 P30519 1 +Regulation of calcium ion transport 0.5259028239200245 1.8966052791587165 0.0578800533277628 1.0 0.5714832297891764 32 P62942,P21796,P30536,P78417 4 +Regulation of response to food 0.986474301172227 1.896585074428379 0.0578827220205699 1.0 0.5714832297891764 2 Q9UMX5 1 +Negative regulation of response to food 0.986474301172227 1.896585074428379 0.0578827220205699 1.0 0.5714832297891764 2 Q9UMX5 1 +Regulation of appetite 0.986474301172227 1.896585074428379 0.0578827220205699 1.0 0.5714832297891764 2 Q9UMX5 1 +Cellular ion homeostasis 0.4386942784693532 1.892872103703744 0.0583748798672296 1.0 0.5714832297891764 86 P62942,P50897,Q8N511,P78417,Q93050,Q8WWC4,P02786,P42858,Q9HD20,Q9NQ11,P09601,O75503,Q9Y487,Q00535,P28482,Q9HC07,O75880,Q9Y639 18 +Regulation of oxidative phosphorylation 0.698648484034503 1.89231927447458 0.0584484543750694 1.0 0.5714832297891764 10 P14406,Q9BSK2 2 +Regulation of ryanodine sensitive calcium release channel activity 0.815752824433289 1.8905914344081731 0.0586789045504003 1.0 0.5714832297891764 6 P62942 1 +Lipid localization 0.4333762607062998 1.8882079536351868 0.0589980384815911 1.0 0.5714832297891764 80 P14174,Q86Y82,Q9UHB6,Q16739,Q8WTV0,Q5SW96,P07602,O15118,P35790,Q14108,Q14534,P17900,Q9BUR5,Q9H4L5,O43772,P04062,P08183,Q99720,P23786,P31749,P30536,Q7Z3C6,Q9P260,P04083,Q01469,P10909,O95674 27 +Maintenance of location 0.4307542164719748 1.887567992477815 0.0590839704290693 1.0 0.5714832297891764 73 P62942,P78417,O95674,Q8WTV0,P31749,O43731,P30536,P24390,P04062 9 +Mitochondrial genome maintenance 0.7040485734801458 1.8861558577623 0.059273954972586 1.0 0.5714832297891764 9 Q9BSK2,P51530,O60313 3 +Negative regulation of immune response 0.546218351358058 1.883282287622456 0.0596621225010458 1.0 0.5714832297891764 25 Q7Z739,P19474,P28070,Q9H000,P25786,Q9Y3Z3,P46108,P04083,Q9Y4E8,P09601,P04439,P01889,Q9Y5A9 13 +Maternal placenta development 0.8123540923261051 1.876835683080763 0.0605406181771059 1.0 0.5714832297891764 6 P31749,P07858,Q15363,P35613 4 +Protein import into mitochondrial matrix 0.7246466317328136 1.8756951270068505 0.060697155435661 1.0 0.5714832297891764 8 Q99595 1 +Cardiac chamber development 0.5855298001448637 1.8748493773152235 0.0608134480038655 1.0 0.5714832297891764 18 P62942,O75844 2 +Positive regulation of fat cell differentiation 0.7242604087211807 1.8739414611343348 0.0609384940079684 1.0 0.5714832297891764 8 P31749,Q86X55,Q13043,Q92766 4 +Folate transmembrane transport 0.9795611662158096 1.8684945376456268 0.0616931708017074 1.0 0.5714832297891764 2 P41440 1 +Folic acid transport 0.9795611662158096 1.8684945376456268 0.0616931708017074 1.0 0.5714832297891764 2 P41440 1 +Cellular response to molecule of bacterial origin 0.5307811773685317 1.8683543473536115 0.0617126959722273 1.0 0.5714832297891764 29 P14174,O43823,Q8WTV0,P31749,P30536,P28482,Q9NUQ9 7 +Activation of cysteine type endopeptidase activity involved in apoptotic process 0.6150211518076758 1.8678913707320135 0.061777213937789 1.0 0.5714832297891764 15 O95831,Q96A26,Q9BXK5,Q9NR28 4 +Positive regulation of translation 0.4483256530176744 1.8649487373857312 0.0621885900001619 1.0 0.5717607347134761 64 Q7Z739,Q9BRP8,P51116,Q9Y2R0,Q14011,Q9NYY8,P16989,P98179,Q14103,P08670,Q9Y5A9,P67809,Q567V2,P51114,O60506 15 +Smad protein signal transduction 0.6994263804387474 1.8643879261629897 0.0622672471894223 1.0 0.5717607347134761 9 P08670,Q96PK6,Q9UIQ6 3 +Regulation of mrna catabolic process 0.4366039743325515 1.8619295887317504 0.0626130157155073 1.0 0.5734266127850184 87 Q7Z739,Q969T7,P51116,O60506,Q92804,P98175,Q14011,Q92945,P31749,Q9NYY8,P16989,Q14103,Q99729,P08670,Q9Y5A9,P67809,P51114,P35637 18 +Mitochondrion organization 0.489255708969515 1.8595312232309065 0.0629518777879516 1.0 0.5734266127850184 201 Q8N183,Q9H061,Q9Y2R0,Q04837,O75832,P12235,Q9Y2S7,Q96CU9,Q9NS69,Q9NQ11,P53365,O75438,O95168,Q8WWC4,O75153,Q99595,O43676,Q9BUK6,Q9BUR5,P42858,Q69YU5,Q8N4Q1,Q99797,P14406,Q6DKK2,P0DP25,P51530,Q9NUQ9,O75880,P04062,P21796,Q9H4A6,Q9BSK2,P45880,Q15070,Q9Y6M9,P11233,Q9NX63,P31749,P30536,Q96TA2,P52789,P49257,Q9UDX5,Q8N4H5,Q9Y512,O60313,Q5XKP0,P02786,O95831,A6NDU8,O75306,O14925,P55786,O95429,O95140,O14737,Q9H3K2,Q86Y39,Q9Y6C9,P30048,Q00535,Q5JRX3,Q96A26 64 +Regulation of fat cell differentiation 0.6036712661538194 1.859483724648296 0.0629586040831102 1.0 0.5734266127850184 16 Q99523,Q8N4Q0 2 +Positive regulation of endothelial cell proliferation 0.6645945307298733 1.8565989930883549 0.0633682273105888 1.0 0.5755430323845653 12 P31749,O75340,P09601,Q9H2J4 4 +Regulation of response to extracellular stimulus 0.8354521357036795 1.8513286982356412 0.0641222798803322 1.0 0.5783473410317745 5 Q9UMX5 1 +Protein insertion into membrane 0.5281662140362389 1.8498482333982025 0.0643354267443783 1.0 0.5794649948377153 29 P46379,Q15070,Q15629,Q9NS69,O14737,Q8WWC4 6 +Muscle organ development 0.5094742324033665 1.8479792203042524 0.0646053489602116 1.0 0.581090216270934 35 P62942,P09493,P16989,P41440,P51114 5 +Antigen processing and presentation of exogenous antigen 0.7180315350817514 1.845612779260127 0.0649484496340346 1.0 0.5833682322592271 8 Q9UIQ6 1 +Monovalent inorganic cation homeostasis 0.5298327971566723 1.8430132952957463 0.0653270693308587 1.0 0.5859585472853546 28 P50897,Q8N511,Q93050,Q9Y487,O75503,P28482,Q9HC07 7 +Response to oxidative stress 0.4478939599284969 1.8404035019686464 0.0657090197187422 1.0 0.5861461182053735 105 Q9UJ14,P30519,Q15392,Q9NQ11,P28074,O95168,Q16134,P42574,Q9UL15,P00374,P09601,Q7LG56,O15111,O43169,P04062,Q99720,Q7Z2K6,Q6NUK1,O75874,P31749,Q93062,Q15165,Q9NR28,O95831,P46108,P09493,P16615,O75306,P30048,P04083,Q8N0U8,P28482 32 +Positive regulation of actin filament polymerization 0.6405052316545224 1.8384271680951012 0.0659994848317766 1.0 0.5879295672120131 13 O95429,Q9UQB8,Q6ZU35 3 +Regulation of alternative mrna splicing via spliceosome 0.5145088213457752 1.8361086920954317 0.0663415830241476 1.0 0.5893601096563811 33 P51116,Q9BWF3,O75525,P98175,P62995,Q92841,P38159,Q8NDT2,Q8IY67,Q9UHX1,P09651,Q13247,Q06787,Q15007,P51114 15 +Positive regulation of calcium ion transport 0.5891166396290869 1.833748955084008 0.066691268027448 1.0 0.5908500608052494 17 P78417,Q9NRA0,P42858,P30536,O76024,Q00535,P0DP25 7 +Positive regulation of pattern recognition receptor signaling pathway 0.6861360240294456 1.832457935141254 0.0668832233268446 1.0 0.5909720718679128 10 P41440 1 +Maintenance of protein localization in organelle 0.5882906573110694 1.8288794656965597 0.0674176670387758 1.0 0.5948509915078943 17 O94901,P31749,O43731,P30536,Q00535,P52789,P36404,P24390 8 +Intracellular lipid transport 0.6167737745962938 1.825037353546725 0.0679953926895826 1.0 0.5965408966643139 14 Q9P260,P23786,O43772 3 +Endoplasmic reticulum tubular network organization 0.658258680837502 1.824553111104461 0.0680684946763561 1.0 0.5965408966643139 12 Q9H6H4,Q15041,O95197,P57088,Q6NUK4 5 +Cardiac chamber morphogenesis 0.6840027267894022 1.8222123806776416 0.0684227667426919 1.0 0.5966980608967289 10 P62942 1 +Peptidyl proline hydroxylation 0.7121948108688904 1.8189891367365776 0.0689130874366716 1.0 0.5969024799078402 8 P13674,Q32P28,O15460 3 +Negative regulation of transport 0.430818222094088 1.8167793769961855 0.0692509018272791 1.0 0.5969024799078402 85 P62942,P21796,Q16850,P78417,O60343,Q01469,Q16836,O95429,P31749,P04083,P09601,Q8N5M9,P49257,Q9UMY4 14 +Antigen processing and presentation of endogenous antigen 0.7974956416298138 1.816476413513697 0.0692973228521884 1.0 0.5969024799078402 6 P04439,Q9NZ08,Q03518,P10321 4 +Antigen processing and presentation of endogenous peptide antigen 0.7974956416298138 1.816476413513697 0.0692973228521884 1.0 0.5969024799078402 6 P04439,Q9NZ08,Q03518,P10321 4 +Regulation of dephosphorylation 0.4981474857318999 1.81530065757832 0.069477718009284 1.0 0.5969024799078402 37 P62942,P42858,Q86XL3,P04062 4 +Positive regulation of autophagy 0.5014370568371099 1.8131145689309036 0.0698141525807956 1.0 0.5969024799078402 36 P21796,P19474,P12235,Q9BXS4,P09601,O15270 6 +Antigen processing and presentation 0.5358013178149699 1.812863946260903 0.0698528081991936 1.0 0.5969024799078402 25 P10321,P04439,P01889,Q9UIQ6,Q03518,Q9BYJ9,Q9NZ08,P61020,P04062 9 +Folic acid containing compound metabolic process 0.6143906144151405 1.8119023456596113 0.0700012869106225 1.0 0.597356579760293 14 P00374,P41440,Q9H2D1,P34896 4 +Negative regulation of smooth muscle cell proliferation 0.7514261425211842 1.8039851882404052 0.071233628967199 1.0 0.6013642912283319 7 P09601,P09493 2 +Negative regulation of immune effector process 0.6857883078433654 1.799854850604414 0.0718835603555783 1.0 0.6031427384705987 9 P46108,P04083,P09601,P04439 4 +Entry into host 0.5095480452376513 1.799247015062107 0.0719796153856966 1.0 0.6031427384705987 33 P19474,Q9BTY2,Q8WTV0,O15118,P07858,Q9P253,Q14108,P35613 8 +Tetrapyrrole metabolic process 0.5608083082306181 1.7892662657964618 0.0735719441516742 1.0 0.6109486057771092 19 P30519,P09601 2 +Positive regulation of binding 0.4588011083667928 1.7878396395421718 0.0738018835237841 1.0 0.6113130505146099 51 P62942,O75503,P41440 3 +Prenylation 0.819064160113148 1.7857344575512208 0.0741422633985693 1.0 0.6117914339394018 5 P53609,P49356 2 +Reactive nitrogen species metabolic process 0.5801580726888346 1.7807958936793622 0.074945800511498 1.0 0.6121987780146769 17 Q5VT66,Q92945,P31749,P30536,P35270,P06280,O43169 7 +Cristae formation 0.7035409388645779 1.779377129971217 0.0751779533584406 1.0 0.6133236546604445 8 Q5XKP0,Q16891,Q9BUR5,Q9NX63,Q9Y512 5 +Cellular response to biotic stimulus 0.4927526182609498 1.7731383902080646 0.0762057779566498 1.0 0.6178281174163347 37 P14174,O43823,O75844,Q8WTV0,P31749,P30536,P28482,Q9NUQ9 8 +Golgi vesicle budding 0.7014034009662641 1.7695676339418007 0.0767991945840147 1.0 0.6207223681972629 8 Q9H4A6,Q9BVK6,Q92614,P49755,Q9H4A5,Q15363 6 +Regulation of phagocytosis 0.6066782180759774 1.7692658465095037 0.0768495201771788 1.0 0.6207223681972629 14 Q8WTV0 1 +Nad biosynthesis via nicotinamide riboside salvage pathway 0.9546137661556908 1.7668158539403842 0.0772590727285167 1.0 0.6222762770439315 2 P43490 1 +Pyrimidine containing compound catabolic process 0.7427313913969217 1.7663963673372436 0.0773293741260321 1.0 0.6222762770439315 7 Q9H773 1 +Regulation of autophagy of mitochondrion 0.5966918814473607 1.7645797064150608 0.0776344286022365 1.0 0.6231866246513279 15 P21796,Q9NQ11,P12235,P30536 4 +Response to increased oxygen levels 0.6993153780755371 1.7599758137727688 0.0784119075029248 1.0 0.6269999326185595 8 Q8N511,P00846,Q9Y487 3 +Lytic vacuole organization 0.5203290608867931 1.7592344590704423 0.0785376935932833 1.0 0.6269999326185595 27 P50897,O75503,Q9P253,Q9HC07,Q14108,P04062 6 +Regulation of phospholipid catabolic process 0.90721308586062 1.7583623109897752 0.0786858816411415 1.0 0.6269999326185595 4 Q8WTV0 1 +Positive regulation of cysteine type endopeptidase activity 0.5092463066988222 1.7533062021735208 0.0795494614823 1.0 0.6281672743499207 31 Q9BXK5,Q9NR28,O95831,O14737,Q96F07,Q9BXI6,Q9Y3D6,P49327,O75340,Q96A26 10 +Calcium ion transport 0.450081193648866 1.7483110420206824 0.080410182243076 1.0 0.6281672743499207 55 P62942,P21796,P78417,O75844,P42858,P30536,Q00535,Q8WWC4,Q9HC07,Q06787 10 +Modified amino acid transport 0.7805207534515618 1.7470869410403749 0.0806222582753222 1.0 0.6281672743499207 6 O43772,P41440 2 +Xenobiotic metabolic process 0.5923156652609654 1.7397420475131289 0.0819043225530518 1.0 0.6308891565779812 15 P07099,Q96DG6,O15217,O43169 4 +Liposaccharide metabolic process 0.5484512582132346 1.7381265560957897 0.082188516548348 1.0 0.6308891565779812 20 Q16739,P04062,P17900,Q99805,Q9Y2B2,Q8NBX0 6 +Glycosylceramide metabolic process 0.8070352062868156 1.7373518411472788 0.0823250862460209 1.0 0.6311399531106353 5 Q16739,P04062 2 +Glycoprotein biosynthetic process 0.448609028989044 1.7346357312306788 0.0828053464321001 1.0 0.6331940919969542 55 Q86YN1,Q9BXS4,Q14165,Q8NCH0,O15118,P15291,Q6ZXV5,O43505,Q7LGA3,O60502,P26572,O43909,Q13724,Q9H4A6,Q9Y5P6,Q06210,Q10471,O75340,Q9HC07,Q96JB2,O60476,Q99805 22 +Pattern recognition receptor signaling pathway 0.5007957671342432 1.7338514198175845 0.0829444494036308 1.0 0.6331940919969542 33 Q9NPR9,Q9NUD5,P41440 3 +Bone development 0.5188064348824618 1.7329538276514904 0.083103875774944 1.0 0.6333139259221077 26 Q15125,Q7RTS9,Q32P28 3 +Lipopolysaccharide mediated signaling pathway 0.6714053629111367 1.7313104158853383 0.0833964146997079 1.0 0.6333139259221077 9 P14174,P31749,Q8WTV0 3 +Chromosome organization involved in meiotic cell cycle 0.551400119620886 1.730521761698671 0.0835370966087245 1.0 0.6333139259221077 19 P46379,Q92791,O43683,P30153,O60566,Q9BTX1,Q15645 7 +Calcium ion import 0.6190586705373696 1.7247291340737212 0.0845762980652282 1.0 0.6372796349637057 13 P21796,O75844,Q00535,Q8WWC4,P16615 5 +Phosphatidylcholine metabolic process 0.5986447109173991 1.7246466660610666 0.0845911680533899 1.0 0.6372796349637057 14 Q8NCC3,Q8WTV0 2 +Protein processing 0.4541064797376312 1.722776912254311 0.0849288754450812 1.0 0.6385659972853598 48 P78536,O75844,Q9BXS4,Q15392,P67812,Q5JRX3,P42892,Q9BXI6,Q96TA2,O75503,Q9UMY4,P42574,O75976 13 +Nuclear transcribed mrna catabolic process exonucleolytic 0.5798690082248241 1.7218376037404557 0.0850989405876394 1.0 0.6385659972853598 16 Q969T7 1 +L alpha amino acid transmembrane transport 0.6632123962573573 1.721769261983647 0.0851113248446524 1.0 0.6385659972853598 10 Q9Y619 1 +Response to food 0.7742954037610215 1.7215269623987142 0.0851552438634311 1.0 0.6385659972853598 6 P80303,P31749,Q9UMX5 3 +Hormone metabolic process 0.5071096341977103 1.7179289847923338 0.0858095692378877 1.0 0.6412512573427422 30 O75844,Q9UBM7,Q9HB40,P42892,P30536,O95470 6 +Phospholipid transport 0.59731761936064 1.717255649142615 0.0859324716868012 1.0 0.6414315760161927 14 Q8WTV0 1 +Maintenance of protein localization in endoplasmic reticulum 0.9860884289827752 1.7072864286332845 0.0877688273490808 1.0 0.6447319228440188 3 O43731 1 +Protein retention in er lumen 0.9860884289827752 1.7072864286332845 0.0877688273490808 1.0 0.6447319228440188 3 O43731 1 +Dicarboxylic acid metabolic process 0.4684175729701175 1.7067752405432963 0.0878638361128667 1.0 0.6447319228440188 42 Q9H2D1,P00374,O75874,P34896,P48735,P41440 6 +2 oxoglutarate metabolic process 0.6644081249606644 1.697786854811551 0.0895479977963868 1.0 0.6533555406449809 9 P48735 1 +Positive regulation of oxidoreductase activity 0.6580682680646484 1.6967532352324963 0.0897433234147402 1.0 0.6533555406449809 10 P00374,Q8WTV0 2 +Cellular response to exogenous dsrna 0.7265611376260158 1.6961230509495462 0.0898625790972842 1.0 0.6534873389655487 7 Q5KU26,P41440,Q9NUD5 3 +Leukotriene metabolic process 0.7961481134183083 1.6933975032765038 0.0903798298108946 1.0 0.6534873389655487 5 Q9UJ14,Q14914 2 +Sphingoid metabolic process 0.7670779416190209 1.6918203919891108 0.0906802242684037 1.0 0.6534873389655487 6 Q9NRA0,Q06136,Q13510,O15270,P04062 5 +Amino acid transmembrane transport 0.592416348647804 1.68990973865953 0.0910452241814983 1.0 0.6534873389655487 14 Q96QD8,Q96NB2,Q15041,Q9Y619 4 +Regulation of lipid catabolic process 0.6625023799719456 1.688636742341826 0.0912890649533562 1.0 0.6534873389655487 9 O75874,Q8WTV0 2 +Vesicle targeting to from or within golgi 0.5920492775044399 1.6878586249269747 0.0914383706717245 1.0 0.6534873389655487 14 Q15363,O15027,Q9BVK6,Q92734 4 +Manganese ion transport 0.9344755034565646 1.6844404804470752 0.0920965730966554 1.0 0.6534873389655487 2 Q9HD20 1 +Manganese ion transmembrane transport 0.9344755034565646 1.6844404804470752 0.0920965730966554 1.0 0.6534873389655487 2 Q9HD20 1 +Porphyrin containing compound metabolic process 0.5637240984143602 1.6828713375399582 0.0924000013108183 1.0 0.6534873389655487 17 P30519,P09601 2 +Regulation of aerobic respiration 0.5822336019243871 1.6822734091435427 0.0925158349234116 1.0 0.6534873389655487 15 P14406,Q9BSK2 2 +Respiratory chain complex iii assembly 0.7644993200508763 1.68118824126087 0.09272635677114 1.0 0.6534873389655487 6 Q69YU5,Q9BSK2 2 +Regulation of hematopoietic stem cell differentiation 0.6821415707930044 1.6807311423184577 0.0928151487033326 1.0 0.6534873389655487 8 Q96PZ0 1 +Regulation of release of cytochrome c from mitochondria 0.6099916567559118 1.6762481762890364 0.0936895912269297 1.0 0.6538710679539644 13 O75832,P31749,O14737,Q9H3K2,Q96A26,O60313 6 +Cytidine to uridine editing 0.9323715058611368 1.675821662848659 0.093773129594225 1.0 0.6538710679539644 2 A0AV96 1 +Regulation of skeletal muscle tissue development 0.791683094312525 1.675327380108057 0.0938700162094998 1.0 0.6538710679539644 5 P41440 1 +Cotranslational protein targeting to membrane 0.5896798890758931 1.6746086828734297 0.0940110345434133 1.0 0.6538710679539644 14 P43307,Q15629 2 +Isocitrate metabolic process 0.7627463666627148 1.6739549259031072 0.0941394581949892 1.0 0.6538710679539644 6 P48735 1 +Regulation of cytoplasmic translation 0.5622323715460305 1.673933140384785 0.0941437401504399 1.0 0.6538710679539644 17 P16989,Q14103,Q9Y5A9,P67809,O60506 5 +Toll like receptor signaling pathway 0.5804925354955817 1.6723147134323466 0.0944622797968548 1.0 0.6553825267102301 15 Q9NPR9 1 +Adipose tissue development 0.5891113028050252 1.6714264208626728 0.0946374808638801 1.0 0.6557028279538248 14 O15173,P43490 2 +Pyridine containing compound metabolic process 0.6588165855623953 1.6709162847435228 0.0947382144642388 1.0 0.6557028279538248 9 Q13126,P43490 2 +Prostate gland development 0.7202164054841411 1.668423115846152 0.0952317626456853 1.0 0.6572104852508827 7 P07602,Q02790 2 +Glycoside catabolic process 0.7607583508877546 1.665746262323726 0.0957639634251883 1.0 0.6601817181350033 6 Q9BTY2,Q9NUJ1,P08236,P06280,P04062 5 +Response to bacterium 0.4314910299493245 1.6649523677598006 0.0959222591856368 1.0 0.6605717403515645 62 P14174,Q5KU26,Q8WTV0,P42574,P17655,O43823,Q13451,Q9NUQ9,Q9UQB8,P31749,P30536,Q9NZZ3,Q9NZ08,P78536,Q9BTY2,P30048,P04439,P01889,P28482,P08670 20 +Regulation of endothelial cell migration 0.5045071842151723 1.6636185965362584 0.0961886731645453 1.0 0.6606446082059423 28 Q8WTV0,P42785,P31749,P04083,P09601,O75340 6 +Apoptotic cell clearance 0.6568597992352444 1.6614958687715349 0.0966138979451767 1.0 0.6606446082059423 9 Q8WTV0 1 +Mitochondrion distribution 0.7881372348837046 1.6609596009071148 0.0967215606953972 1.0 0.6606446082059423 5 O75153 1 +Positive regulation of dendrite morphogenesis 0.6564075128515363 1.659317219000866 0.0970518873157482 1.0 0.6606446082059423 9 Q9UQB8 1 +L amino acid transport 0.6256256020911287 1.657735647068319 0.0973708354148292 1.0 0.662121680820839 12 Q15041,Q9Y619 2 +Glycosphingolipid metabolic process 0.6248079550005878 1.6535188987988243 0.0982253030803432 1.0 0.6630718484446457 12 Q16739,P17900,P04062,Q99805 4 +Ion transmembrane transport 0.4577745437967831 1.651114327617476 0.0987152322518449 1.0 0.6652537400376012 154 P62942,O75844,Q9UBX3,P12235,Q9HD20,Q9NQ11,Q8WWC4,P00846,Q70HW3,Q06787,Q9Y619,P42858,O43772,Q9UDW1,P41440,P21796,P45880,P78417,Q9H2D1,Q15041,Q9HC07,O95563,P20674,O75964,Q02978,Q9UHG3,Q6P4A7 27 +Establishment of protein localization to mitochondrial membrane 0.5486519765398957 1.650425959420038 0.0988558452627479 1.0 0.6652537400376012 18 Q15070,Q9NS69,O14737,Q8WWC4,Q9Y512 5 +Natural killer cell activation 0.6753900720819159 1.6494092867441474 0.0990638134519916 1.0 0.665963151715563 8 P46379 1 +Pyrimidine deoxyribonucleotide metabolic process 0.756256949370299 1.6471386720631906 0.0995295458979588 1.0 0.6662259490276935 6 Q9H773 1 +Iron ion homeostasis 0.5575820301710162 1.646017038884507 0.0997602510546726 1.0 0.6662259490276935 17 Q9NQ11,P09601,P30519,Q9Y487 4 +Fat cell differentiation 0.4995978642909139 1.645223964543034 0.0999236332542305 1.0 0.6662259490276935 29 Q99523,Q8N4Q0,Q9NZ08 3 +Divalent inorganic cation homeostasis 0.4416550211479576 1.6405993611061036 0.1008806077094097 1.0 0.6681977696961368 52 P62942,P78417,P42858,Q9HD20,O15164,Q9NQ11,Q00535,Q8WWC4,P16615,Q9HC07,Q9Y639 11 +Mitochondrial atp synthesis coupled proton transport 0.64002555114684 1.6384040807044131 0.101337428468943 1.0 0.6681977696961368 11 P00846 1 +Organic cation transport 0.8751753686373475 1.635996755895912 0.1018402663530997 1.0 0.6681977696961368 4 Q70HW3,O43772 2 +Negative regulation of leukocyte mediated immunity 0.7816065543756354 1.634457722570154 0.102162776480446 1.0 0.6681977696961368 5 P46108,P09601,P04439 3 +Regulation of cellular respiration 0.5556210947752253 1.6342220783456716 0.1022122282746347 1.0 0.6681977696961368 17 P14406,Q9BSK2 2 +Inorganic anion transmembrane transport 0.7528249886706124 1.6329325777251718 0.1024831775496082 1.0 0.6681977696961368 6 Q9UBX3,Q9UHG3,Q02978,P51790 4 +Water soluble vitamin metabolic process 0.5545585168739202 1.6278249451450568 0.1035620095795322 1.0 0.6718433239336211 17 P78417,Q9H2D1,P00374,P34896,P41440 5 +Cell migration involved in sprouting angiogenesis 0.669811763282388 1.6234603848278073 0.1044910252884394 1.0 0.6718433239336211 8 P31749,P09601 2 +Antigen processing and presentation of exogenous peptide antigen via mhc class i 0.871837803198817 1.623199629779465 0.1045467369757089 1.0 0.6718433239336211 4 Q9UIQ6 1 +N terminal protein amino acid modification 0.6421941760467288 1.6191606727678245 0.1054126972066709 1.0 0.6738022306568107 10 Q9BV86 1 +Regulation of glucosylceramidase activity 0.918545235948298 1.619137041622636 0.1054177804661717 1.0 0.6738022306568107 2 Q14108 1 +L serine catabolic process 0.91794409377818 1.6166708858695076 0.1059493416365748 1.0 0.6758693758231015 2 P34896 1 +Chloride transport 0.6349221465714303 1.613009220398959 0.1067425046106693 1.0 0.6770031733012218 11 P08183,P51790,Q9H813,P54105,Q9UHG3,P30536,Q96S66 7 +Female sex differentiation 0.5784818139311094 1.6117487483468709 0.1070166249851767 1.0 0.6770031733012218 14 O15360,O95470,O75874 3 +Development of primary female sexual characteristics 0.5784818139311094 1.6117487483468709 0.1070166249851767 1.0 0.6770031733012218 14 O15360,O95470,O75874 3 +Positive regulation of cellular amide metabolic process 0.4050667150170053 1.6115250543699822 0.1070653309178248 1.0 0.6770031733012218 73 Q7Z739,Q9Y2R0,P15260,P11940,P16989,Q14103,Q9BYJ9,Q9Y5A9,Q06787,P42574,Q567V2,O60506,P67809,P51114,Q14011,Q9NYY8,Q9NRA0,P51116,Q96SZ6,P98179,P10909,P08670,Q9BRP8 23 +Vitamin metabolic process 0.5111684166679248 1.6109597412354295 0.1071884974591965 1.0 0.6771226678015783 24 P78417,Q9H2D1,P00374,P38435,P34896,Q8N0U8,P41440,P04062 8 +Positive regulation of calcium ion transmembrane transporter activity 0.6668223783046605 1.6095289756969635 0.1075007243875292 1.0 0.6777764118180726 8 P42858,P78417,Q00535 3 +Inflammatory response 0.4092224842438282 1.6089944838414334 0.1076175478002436 1.0 0.6778548549124952 71 P14174,P28070,Q9H000,P25786,P02786,P60900,Q8IV08,O15360,P42785,P31749,P04083,P09601,Q8N2K0,P49327,O15111,P15291,P04062 17 +Positive regulation of cation channel activity 0.6662434379461198 1.6068289070964177 0.108091905153191 1.0 0.6785307862512402 8 P42858,P78417,Q00535 3 +Polyol biosynthetic process 0.5775903694081741 1.6067279557308825 0.1081140582889497 1.0 0.6785307862512402 14 P00374,P35270,P04062 3 +Pyrimidine nucleoside triphosphate metabolic process 0.5770213725297557 1.6035219810975168 0.1088194601536505 1.0 0.680228901183151 14 Q9H773 1 +Regulation of lipase activity 0.5769121598800985 1.6029065166620438 0.1089552947402767 1.0 0.680228901183151 14 P50897,P18085,P40616,Q9Y263,Q99523,P20248,P04083 7 +Atp synthesis coupled proton transport 0.6142297003623385 1.5988077027302832 0.1098633370048136 1.0 0.6811708011103846 12 P00846 1 +Hematopoietic stem cell differentiation 0.6138850019255424 1.5970200535838626 0.1102612371899942 1.0 0.6819394993445931 12 Q96PZ0 1 +Inner mitochondrial membrane organization 0.5177868211638537 1.5948159922096037 0.1107533897792729 1.0 0.6829499201612914 22 Q5XKP0,O95202,Q16891,Q9BUR5,Q9NX63,Q9H3K2,Q8WWC4,Q9Y512,O60313 9 +Negative regulation of cellular amide metabolic process 0.4233285145859266 1.594405349656714 0.1108452750000001 1.0 0.6829499201612914 102 Q7Z739,Q969T7,P51116,Q16799,O95197,Q96PZ0,P00374,Q14011,Q92945,P34896,P34897,Q14103,P06730,Q9Y5A9,P67809,P51114,O60506 17 +Peripheral nervous system axon regeneration 0.8640638046983038 1.593359731032968 0.111079513989079 1.0 0.6830969354593551 4 P30536,Q96G23 2 +Labyrinthine layer development 0.642410928822198 1.591669716516403 0.1114589362216234 1.0 0.6834133553662715 9 P31749,Q15363,P28482 3 +Response to auditory stimulus 0.911331529906816 1.5895360313239002 0.1119394260634711 1.0 0.6844958878118472 2 Q8N2K0 1 +Adult locomotory behavior 0.5740888009826135 1.5869829738317245 0.1125165008515791 1.0 0.6867313501223262 14 P50897,O75844,P04080,O15118,Q8N2K0 5 +Collagen metabolic process 0.6293148765565524 1.585035957301334 0.1129581648329458 1.0 0.6884410411985065 11 P08670,P07858,Q32P28,Q92791 4 +Negative regulation of fat cell differentiation 0.7002736791605115 1.5809128438211886 0.1138979671889317 1.0 0.6884410411985065 7 Q8N4Q0 1 +Tor signaling 0.4949459634758046 1.5797102741866922 0.1141732316560744 1.0 0.6884410411985065 27 O75844,Q8IWV7,P31749,Q9Y2Q5,O75340,P04062 6 +Neuron projection regeneration 0.6104032770575148 1.5789464936947233 0.1143483303963974 1.0 0.6884410411985065 12 P00374,P30536,Q96G23,P11047 4 +Regulation of synaptic vesicle exocytosis 0.6280518104271448 1.578724697664755 0.114399217315932 1.0 0.6884410411985065 11 P35080,Q4J6C6,Q00535,Q9P253,P16615,P0DP25,Q06787 7 +Glucosylceramide metabolic process 0.8598522099171692 1.5771758922346877 0.1147550584761449 1.0 0.6884410411985065 4 P04062 1 +Peripheral nervous system development 0.6333291456459909 1.5755751233069295 0.115123752946626 1.0 0.6884410411985065 10 P31749,P51648,P11047,Q9NR77 4 +Sphingosine biosynthetic process 0.7668471720818462 1.5743826976883255 0.115399001438726 1.0 0.6884410411985065 5 Q13510,Q9NRA0,O15270,P04062 4 +Deoxyribose phosphate metabolic process 0.5629641944489369 1.5715033721464648 0.1160657717461219 1.0 0.6884410411985065 15 Q9H773,Q7LG56 2 +Outer mitochondrial membrane organization 0.7657400981955564 1.5698669557140208 0.1164460666052029 1.0 0.6884410411985065 5 Q9NS69,O14737 2 +Nadp metabolic process 0.5626417746082288 1.5696398230475876 0.1164989283585973 1.0 0.6884410411985065 15 O75874,P48735 2 +Regulation of neuron projection development 0.3989674618810446 1.5695627372328504 0.1165168732206403 1.0 0.6884410411985065 74 Q9UL15,Q32P28,Q96G23,Q9UQB8,P46108,Q9NR77,P31749,Q02790,P07196,Q8N0X7,Q9UJX6,Q15428,Q00535,P08670,O60828,Q14108,Q9Y639 17 +Embryo implantation 0.6319536119035598 1.5687964140498327 0.1166953842526949 1.0 0.6884410411985065 10 Q02790,Q8IZL8,P35613 3 +Proteoglycan metabolic process 0.6580698526836861 1.5686393775221343 0.1167319916074336 1.0 0.6884410411985065 8 Q8NCH0,O43909,Q99805 3 +Cardiac muscle tissue morphogenesis 0.8574885476758681 1.5680878260045965 0.1168606372567289 1.0 0.6884410411985065 4 P62942 1 +Ventricular cardiac muscle tissue morphogenesis 0.8574885476758681 1.5680878260045965 0.1168606372567289 1.0 0.6884410411985065 4 P62942 1 +Muscle organ morphogenesis 0.8574885476758681 1.5680878260045965 0.1168606372567289 1.0 0.6884410411985065 4 P62942 1 +Sensory perception of light stimulus 0.5256742227843477 1.5680505077429334 0.1168693455079032 1.0 0.6884410411985065 19 P50897,P11047,Q15555,Q9H6K4,P53611,O60313 6 +Pyridine containing compound biosynthetic process 0.736016236201795 1.5631230451644058 0.1180236561321259 1.0 0.6904915521820053 6 P43490 1 +Cellular response to increased oxygen levels 0.7638203596514866 1.562033311102218 0.1182801417014569 1.0 0.6906167728193624 5 Q8N511,Q9Y487 2 +Positive regulation of mitochondrion organization 0.5127277635330694 1.5612276908474092 0.118470037645475 1.0 0.6906167728193624 22 P21796,P42858,P12235,P11233,Q96A26 5 +External encapsulating structure organization 0.4919702125446901 1.5584506859804048 0.1191264493568637 1.0 0.6906167728193624 27 P11047,Q92791,P13674,Q96AY3,P41440 5 +Ion homeostasis 0.4228336857472398 1.5578576380915283 0.1192669991217643 1.0 0.6906167728193624 106 P62942,P50897,P30519,Q9HD20,Q9NQ11,Q9Y6N1,Q9Y487,Q8WWC4,Q93050,P42858,O15164,Q9Y5X3,P09601,O75503,O75880,Q8N511,P78417,P30536,Q9HC07,Q9Y639,P02786,P16615,Q00535,P28482 24 +Proteoglycan biosynthetic process 0.695018421699152 1.5577448750435925 0.119293738169707 1.0 0.6906167728193624 7 Q8NCH0,O43909,Q99805 3 +Regulation of hematopoietic progenitor cell differentiation 0.6236384569432465 1.556643286493994 0.1195552005912818 1.0 0.6906167728193624 11 Q96PZ0 1 +Modification of synaptic structure 0.654870126260618 1.5536545091305924 0.1202668495841647 1.0 0.6923873414889771 8 Q7L576,Q9UQB8,O00264 3 +Negative regulation of inflammatory response to antigenic stimulus 0.7606513877226179 1.5490937338897226 0.1213591890030469 1.0 0.695168301627998 5 P28070,P25786,Q9H000 3 +Regulation of cell killing 0.6334199345201099 1.5479896671085869 0.1216247843064388 1.0 0.695168301627998 9 P46108,P01889,Q9NUQ9,P04439 4 +Homologous chromosome pairing at meiosis 0.6331724502523136 1.5467849200521049 0.121915117708752 1.0 0.695168301627998 9 Q15645,P46379,Q9BTX1,Q92791 4 +Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress 0.5581912568937403 1.5438832709164898 0.1226166135160597 1.0 0.6954343128151025 15 O95831,P46379,O60313 3 +Regulation of systemic arterial blood pressure mediated by a chemical signal 0.7588837145213311 1.5418715240258858 0.1231048169890192 1.0 0.6964595860858436 5 P42892 1 +Response to estrogen 0.584952346752776 1.5411446320046205 0.1232815893909611 1.0 0.6964595860858436 13 Q969T9,P09601,P04062 3 +Transition metal ion homeostasis 0.5008102459115695 1.5400502196939465 0.1235481125917603 1.0 0.6964595860858436 24 P30519,Q9NQ11,P09601,Q9Y487,O75880 5 +Decidualization 0.8987075443342344 1.537705509989104 0.1241206358150357 1.0 0.6974961541066642 2 P35613 1 +Cellular response to chemical stress 0.402839207227646 1.537481011402616 0.1241755615249555 1.0 0.6974961541066642 82 Q9NQ11,P16989,P42574,Q9UL15,P00374,P09601,O15111,P04062,Q99720,Q7Z2K6,Q6NUK1,P31749,P30536,P49327,Q9NR28,O95831,P09493,P16615,P30048,P04083,Q8N0U8,P28482 22 +Regulation of cysteine type endopeptidase activity 0.4312741215125935 1.5369264974476715 0.1243113098943207 1.0 0.6974961541066642 51 Q9BXK5,Q15041,Q9NR28,O95831,Q15392,P31749,O14737,Q9BXI6,Q96K76,P49327,O75340,Q96A26 12 +Positive regulation of autophagy of mitochondrion 0.7576432557276294 1.5368015005990054 0.1243419258621949 1.0 0.6974961541066642 5 P21796,P12235 2 +Phosphatidylserine metabolic process 0.8490220000319618 1.5355055181144008 0.1246597026789309 1.0 0.6974961541066642 4 Q8NCC3 1 +Golgi ribbon formation 0.6899324739315724 1.5352826323361908 0.124714418374203 1.0 0.6974961541066642 7 O43752,Q92614 2 +Tetrahydrobiopterin metabolic process 0.8475840312989107 1.5299673987383853 0.1260247987753742 1.0 0.6974961541066642 4 P00374 1 +Negative regulation of neuron projection development 0.5156630733571779 1.5278118684875084 0.1265592546533136 1.0 0.6974961541066642 20 Q96G23,Q9NR77,Q02790,Q00535,Q8N0X7,P08670 6 +Homologous chromosome segregation 0.6234690807559605 1.5268926063936774 0.1267877184004673 1.0 0.6974961541066642 10 O94901,P46379,Q92791,Q9BTX1,Q15645 5 +Negative regulation of establishment of protein localization 0.4942832285681964 1.526882127706944 0.1267903245125594 1.0 0.6974961541066642 25 Q16850,Q16836,O95429,Q00535,Q8N5M9,P49257,Q9UMY4 7 +Purine containing compound transmembrane transport 0.6876840679122618 1.5253400137240285 0.1271743123002673 1.0 0.6974961541066642 7 P41440 1 +Negative regulation of release of cytochrome c from mitochondria 0.6864784911750944 1.5200057680295913 0.1285095259695394 1.0 0.698180651752521 7 P31749,O75832,Q9H3K2,O60313 4 +Vascular transport 0.5981060825745186 1.514870905190323 0.1298050997332358 1.0 0.7011496813762326 12 P08183,P53985,Q96QD8,P41440,Q01469 5 +Pyrimidine containing compound metabolic process 0.4792930874383796 1.5137871062798745 0.1300798438554025 1.0 0.7011496813762326 30 Q9NRW3,Q9H773,P17812,P34896,Q9H0P0,P28482 6 +Negative regulation of vascular associated smooth muscle cell proliferation 0.7518913369292467 1.5132726085699435 0.1302104274314346 1.0 0.7011496813762326 5 P09601 1 +Regulation of leukocyte mediated cytotoxicity 0.6458412478933282 1.5112685576701352 0.1307200414258358 1.0 0.7027284346186903 8 P46108,P01889,Q9NUQ9,P04439 4 +Quaternary ammonium group transport 0.8917944093778069 1.509313540809855 0.1312186759551441 1.0 0.7036615042549182 2 O43772 1 +Amino acid betaine transport 0.8917944093778069 1.509313540809855 0.1312186759551441 1.0 0.7036615042549182 2 O43772 1 +Regulation of monooxygenase activity 0.596898782791016 1.5085603847763902 0.1314111643221538 1.0 0.7041122946436197 12 P00374,Q8WTV0 2 +Regulation of oxidoreductase activity 0.5118295742427763 1.5029419977041036 0.1328540017547239 1.0 0.7058239363579779 20 P00374,Q15070,Q8WTV0 3 +Glycoside metabolic process 0.6440576609908888 1.5028781123763153 0.1328704781547194 1.0 0.7058239363579779 8 Q9BTY2,Q9NUJ1,P04062 3 +Glucose import 0.5955363361155485 1.501434765206486 0.1332431476263993 1.0 0.7058239363579779 12 P31749,Q99523,Q16539,P52789 4 +Transmembrane receptor protein serine threonine kinase signaling pathway 0.4293715890505912 1.5003949421310805 0.1335121289269953 1.0 0.706048668771912 48 P62942 1 +Positive regulation of anion transport 0.6815114724084002 1.4980060865709806 0.1341316690947676 1.0 0.7076730412543595 7 P08183,P14174,Q15041,Q9Y4C2 4 +Negative regulation of protein polymerization 0.4834794065061731 1.4975529414229165 0.134249440960398 1.0 0.7076730412543595 27 P45880,Q9NUQ9 2 +Regulation of hormone levels 0.4046292598911106 1.4969756848058826 0.1343995850400556 1.0 0.7078596149636022 68 Q8N183,P53985,O75844,Q16836,Q9UBM7,Q9HB40,P42892,P07858,P30536,P04083,Q8N5M9,Q53GQ0,O95470,O95563 14 +G quadruplex dna unwinding 0.7470452977151992 1.4934252630092206 0.1353259041246872 1.0 0.7110084315418439 5 P51530 1 +Retrograde transport endosome to golgi 0.4520301404246076 1.4925172611498114 0.135563595602562 1.0 0.7116814792587209 39 Q9BVK6,Q4J6C6,Q9Y5X3,O75503,P49257,O43752,Q9UMY4,Q8NBN3 8 +Response to granulocyte macrophage colony stimulating factor 0.8869852720168261 1.4895618242047748 0.1363394861156632 1.0 0.7143061253638068 2 P31749 1 +Ceramide transport 0.7459184666744991 1.488807204831444 0.1365381445417186 1.0 0.7143061253638068 5 P07602 1 +Negative regulation of leukocyte migration 0.6410049758143127 1.4885045121374365 0.1366178930948662 1.0 0.7143061253638068 8 P31749,P09601 2 +Determination of adult lifespan 0.6792783742672566 1.4881038203233068 0.1367235161421638 1.0 0.7143061253638068 7 O75844 1 +Neurofilament cytoskeleton organization 0.886083558761648 1.4858584456626296 0.1373165669827116 1.0 0.7157656403741507 2 P07196 1 +Multicellular organismal response to stress 0.6403378039504622 1.4853609658911222 0.1374482299601438 1.0 0.715788937739514 8 P31749,P06730 2 +Regulation of muscle organ development 0.7171168896854927 1.4842018865532474 0.1377553694681024 1.0 0.7168135972162316 6 P41440 1 +Phosphatidylcholine catabolic process 0.8349846615682013 1.481395088312421 0.1385013228147844 1.0 0.7183926440568771 4 Q8WTV0 1 +Glycine metabolic process 0.6393002157903469 1.4804705862977807 0.1387477047429621 1.0 0.7185228027119588 8 P00374,P34896 2 +Ceramide catabolic process 0.6770808303606599 1.4783523763390929 0.139313485334694 1.0 0.7197309258261757 7 Q13510,P17900,P04062 3 +Branching involved in labyrinthine layer morphogenesis 0.8839795611662065 1.477217422375299 0.1396173650576875 1.0 0.7198494210652404 2 Q15363 1 +Positive regulation of vasculature development 0.5107273788139816 1.4724749190954685 0.1408926750106067 1.0 0.7228009448453478 19 Q9H2J4,P09601,P52789,Q9NZ08 4 +Mitochondrial electron transport ubiquinol to cytochrome c 0.7419328511272618 1.472464227885394 0.1408955600750596 1.0 0.7228009448453478 5 O14949 1 +Succinate transmembrane transport 0.882476705740898 1.4710454837046023 0.1412788167548577 1.0 0.7235525520552416 2 Q02978 1 +Oxaloacetate transport 0.882476705740898 1.4710454837046023 0.1412788167548577 1.0 0.7235525520552416 2 Q02978 1 +I kappab kinase nf kappab signaling 0.4183524563060198 1.4698864446601192 0.1415925114383645 1.0 0.7241123583893332 57 P62942,P19474,O43657,P09601 4 +Fatty acid elongation 0.8821761346558401 1.4698111228763344 0.1416129158331909 1.0 0.7241123583893332 2 Q9NZ01 1 +Oxidative phosphorylation 0.4080774170942923 1.4618903972413 0.1437712468529977 1.0 0.7299212104782175 64 Q9BSK2,O43676,P20674,O75964,Q9Y6M9,Q9UDW1,O75306,P34897,O75438,O95168,Q9H3K2,P00846,P14406,O14949 14 +Glial cell proliferation 0.7116742956369635 1.4613975064380924 0.1439063846252009 1.0 0.7299212104782175 6 Q96G23,P04062 2 +Glycolipid biosynthetic process 0.6101512707794081 1.4608113466809227 0.1440672210681823 1.0 0.7299212104782175 10 Q16739,Q99805,Q8NBX0 3 +Purine nucleotide transport 0.6154720462806755 1.46029748569776 0.1442083327754162 1.0 0.7299212104782175 9 P41440 1 +Detection of biotic stimulus 0.6726692129232569 1.4587561034552272 0.1446322483759718 1.0 0.7301882121636786 7 Q8WTV0 1 +Glycine biosynthetic process 0.9182200841852018 1.455389150666244 0.1455615582641294 1.0 0.7313233296054426 3 P00374,P34896 2 +C4 dicarboxylate transport 0.6717301200070642 1.4545812940512337 0.1457852127227066 1.0 0.7313233296054426 7 Q9UJS0,Q02978,Q9UBX3 3 +Carbohydrate derivative catabolic process 0.4557540017127733 1.45457587561895 0.145786713698979 1.0 0.7313233296054426 36 Q9NRW3,Q9H773,Q9NUJ1,O60502,Q13126,P04062 6 +Nucleoside phosphate catabolic process 0.5169557363817066 1.453412223822231 0.1461093345512385 1.0 0.7313233296054426 18 Q9H773 1 +Autophagy of mitochondrion 0.4553355505131493 1.4512325814331537 0.1467151072232295 1.0 0.7313233296054426 36 P21796,Q7Z3C6,P42858,A6NDU8,P12235,Q9NQ11,P53365,Q5MNZ6,Q9UII2,P30536,P52789,Q9Y3D6,O95140,P04062 14 +Neurotransmitter transport 0.4787181315639824 1.4501207317510043 0.14702485477327 1.0 0.7313233296054426 26 P50897,Q96QD8,Q4J6C6,Q00535,Q9P253,P41440,P16615,O95721,Q06787 9 +Positive regulation of calcium ion transport into cytosol 0.6328519023235311 1.4500373966839455 0.1470480910203857 1.0 0.7313233296054426 8 P42858,P78417 2 +Positive regulation of release of sequestered calcium ion into cytosol 0.6328519023235311 1.4500373966839455 0.1470480910203857 1.0 0.7313233296054426 8 P42858,P78417 2 +Cellular modified amino acid catabolic process 0.6324987767077763 1.4483688018553191 0.1475139351511125 1.0 0.7313233296054426 8 Q9UHG3,Q8N2K0 2 +Amino acid transport 0.5159500172843694 1.4471033396498536 0.1478679828226559 1.0 0.7313233296054426 18 Q9UJS0,Q96NB2,Q15041,Q9Y619,Q96QD8,Q6P4A7 6 +Regulation of transmission of nerve impulse 0.8764652840396678 1.4463605701451636 0.1480760951089346 1.0 0.7313233296054426 2 P04062 1 +Regulation of neuronal action potential 0.8764652840396678 1.4463605701451636 0.1480760951089346 1.0 0.7313233296054426 2 P04062 1 +Regulation of anion transport 0.5675564786035906 1.4462901650639288 0.1480958331057476 1.0 0.7313233296054426 13 P08183,P14174,Q15041,Q13546,Q9Y4C2 5 +Ensheathment of neurons 0.4818944879617031 1.4399812966212229 0.1498726906985357 1.0 0.7373282222699173 25 P17028,P53634,Q13144,Q9NR77,P31749,O15228,P10909,Q92542,Q7L576,Q15058,P49770 11 +Protein trimerization 0.8227631729819718 1.4342099175886678 0.1515123677230909 1.0 0.7425821252783039 4 Q99720 1 +Embryonic heart tube development 0.7049059695851818 1.432994384462862 0.1518594421330263 1.0 0.7437218832668728 6 P42892 1 +Response to reactive oxygen species 0.441592389600367 1.4292790202765489 0.1529240535058857 1.0 0.7470372095800673 40 Q99720,O95831,P00374,P46108,P09493,P31749,P30048,P04083,P09601,P28482,P42574,O15111 12 +Positive regulation of cytoplasmic translation 0.5816893508286692 1.4287723258309275 0.1530696821170829 1.0 0.7470372095800673 12 P16989,P67809,Q14103,O60506 4 +Adaptive immune response 0.4224692850270831 1.42876194093082 0.1530726679350198 1.0 0.7470372095800673 46 O96028,Q9UQ84,P78536,Q7KZ85,P10321,Q96FW1,Q03518,P04083,Q9NZ08,Q96FZ2,Q9NUQ9 11 +Negative regulation of blood pressure 0.8200322907178128 1.423658893917958 0.1545452384256829 1.0 0.7484904489307149 4 P42785 1 +Neutrophil differentiation 0.8199143496472192 1.4232031641650258 0.1546772686271973 1.0 0.7484904489307149 4 P49327,Q14739 2 +Mitophagy 0.5369868064043462 1.4203521522694649 0.1555051852066995 1.0 0.7502605295188014 15 P21796,P12235,O95140 3 +Positive regulation of calcium ion transmembrane transport 0.5794790367398432 1.4171341696742072 0.1564437040415673 1.0 0.7511156654355611 12 P42858,P78417,Q00535 3 +Lipid homeostasis 0.4682151444361271 1.4154805009233893 0.1569276615507491 1.0 0.7511156654355611 29 Q86YV9,Q8WTV0,Q15067,Q9NQ11,Q5BJF2,Q9Y6C9 6 +Acetyl coa biosynthetic process from pyruvate 0.7004345860272143 1.4142050350902375 0.1573017100388609 1.0 0.7511156654355611 6 O95563 1 +Mitochondrial fusion 0.5352251713435936 1.4100317350231375 0.1585303124937491 1.0 0.7547623528844626 15 P02786,Q9NX63,O95140,Q9Y6C9,O60313 5 +Regulation of tor signaling 0.4937280554799385 1.4085279659616092 0.1589747919494395 1.0 0.7551063460181626 21 O75844,Q8IWV7,Q9Y2Q5,O75340,P04062 5 +Regulation of mitophagy 0.6990747050548903 1.4084868222121745 0.1589869663340983 1.0 0.7551063460181626 6 P21796 1 +Myotube differentiation 0.5265223942216885 1.4062728092782522 0.159643131037644 1.0 0.7565205429714764 16 Q99523,Q8IV08,P41440 3 +Cellular response to dsrna 0.5991644189771357 1.4060304938638708 0.1597150699744216 1.0 0.7565205429714764 10 P41440 1 +Negative regulation of protein modification by small protein conjugation or removal 0.4463665204800709 1.402860153457182 0.1606585450674384 1.0 0.7567529647069232 37 P19474,Q9UL15,Q6DKJ4,O95071,Q96FW1,P31749,P30536,O60566,Q00535,Q04323 10 +Sulfur compound transport 0.6599108327337848 1.401940902477407 0.1609328949531687 1.0 0.7567529647069232 7 Q02978,Q70HW3 2 +Peptidyl lysine hydroxylation 0.6598258473440332 1.4015617726243894 0.1610461490584547 1.0 0.7567529647069232 7 Q96AY3 1 +Organophosphate catabolic process 0.4407873321371455 1.3994510327449536 0.1616777725987719 1.0 0.757529188496699 39 Q9H773,O75874,Q8WTV0,Q8NCC3,Q8N2K0 5 +Copi coated vesicle budding 0.7237305127596761 1.3976667041353898 0.1622131772477797 1.0 0.7593817355243788 5 Q15363 1 +Vesicle targeting rough er to cis golgi 0.5916975035363423 1.3955689399360682 0.1628443411260334 1.0 0.7601290208915562 11 Q15363,O15027,Q92734 3 +Negative regulation of protein secretion 0.6019670795771528 1.3939069484191522 0.1633457057661571 1.0 0.7608306265376759 9 Q16850,Q16836,Q8N5M9 3 +Toll like receptor 3 signaling pathway 0.7226361285303264 1.3931622244067738 0.1635707401131643 1.0 0.7608306265376759 5 P41440 1 +Negative regulation of secretion 0.5071866334412978 1.391991288088877 0.1639250360945656 1.0 0.7608306265376759 18 Q16850,Q16836,P04083,P09601,Q8N5M9,Q06787 6 +Glycoprotein metabolic process 0.4027137180078688 1.3917768039084446 0.1639899962465265 1.0 0.7608306265376759 63 Q86YN1,Q9BXS4,Q14165,Q8NCH0,O15118,P15291,Q6ZXV5,O43505,Q7LGA3,O60502,P26572,O43909,Q13724,Q9H4A6,Q9Y5P6,Q06210,Q10471,O75340,Q9HC07,Q96JB2,O60476,Q99805 22 +T cell homeostasis 0.6573833291461941 1.3906617806452184 0.164328012399354 1.0 0.7609463018973316 7 P49327,P31749,P42574 3 +Maternal process involved in female pregnancy 0.5960433527794604 1.3904275495483824 0.1643990855500394 1.0 0.7609463018973316 10 Q8IZL8,P31749,P07858,Q15363,P35613 5 +Modification of postsynaptic actin cytoskeleton 0.7218443059761821 1.3899026218097277 0.1645584493737637 1.0 0.761141431790044 5 Q7L576,Q9UQB8 2 +Labyrinthine layer blood vessel development 0.7211954403160707 1.387231226765175 0.165371266360188 1.0 0.7638129471856766 5 P31749,Q15363 2 +Regulation of protein modification by small protein conjugation or removal 0.3933460005582501 1.386329623884304 0.165646275095683 1.0 0.7639963852779588 87 P62942,O75832,Q04323,Q96DY7,O00571,Q9UL15,P53350,Q9Y263,Q96FW1,P19474,Q6DKJ4,O95071,Q9BUN8,Q9BTE7,P31749,P30536,O60566,Q16763,O75340,P26368,Q00535 21 +Deoxyribonucleoside triphosphate metabolic process 0.5941219764419853 1.380813442518373 0.1673363292157412 1.0 0.765808401639904 10 Q9H773 1 +Endothelial cell migration 0.4461415385522578 1.3775217690395942 0.1683509891374277 1.0 0.7672079462866357 36 P42785,P09601,Q8WTV0 3 +Protein k48 linked deubiquitination 0.593340905553243 1.376903287522491 0.1685421506708952 1.0 0.767540481386251 10 Q96FW1,Q9H8M7,Q9Y4E8 3 +Regulation of metal ion transport 0.4060140658330711 1.3718995135356742 0.1700947218703941 1.0 0.7712283683025107 59 P62942,P21796,P78417,P31749,P30536 5 +Pyridine nucleotide biosynthetic process 0.8957539243679593 1.371765902982496 0.1701363250004899 1.0 0.7712283683025107 3 P43490 1 +Positive regulation of macroautophagy 0.4764730223848819 1.3716151184884922 0.1701832848440865 1.0 0.7712283683025107 24 P21796,O15270,P12235,P09601 4 +Glyoxylate metabolic process 0.894634028946858 1.3675981515709084 0.1714378953726099 1.0 0.7763721705367703 3 P48735 1 +Negative regulation of neuron apoptotic process 0.4635700687681329 1.3666865514475082 0.1717235750018702 1.0 0.7771239693812857 28 P50897,P51858,Q01105,O95630,P07196,P09601,Q04446,Q15058,P04062 9 +Plasma lipoprotein particle clearance 0.552749148529266 1.3649684131099054 0.1722629780274824 1.0 0.7771820430337294 13 Q92945,P09601,Q8WTV0 3 +Endoplasmic reticulum organization 0.4187260193740169 1.364359431733485 0.1724544693581158 1.0 0.7771820430337294 45 Q9H6H4,Q8N4V1,Q15041,P46379,O95197,O15027,Q9P2W9,Q15629,P57088,Q96A33,Q15363,Q8N5M9,P49257,Q6NUK4,Q8NHH9 15 +Protein insertion into er membrane 0.5685721663096495 1.3595558487985822 0.1739705178093178 1.0 0.7778442734859667 12 Q15629 1 +Positive regulation of chemokine production 0.6503702730616606 1.3593276657954676 0.1740427810560312 1.0 0.7778442734859667 7 P14174,P09601,P78536 3 +Regulation of transmembrane transport 0.3843591517397743 1.3590467242017334 0.1741317832063982 1.0 0.7778442734859667 79 P62942,P21796,P08183,P78417,Q9NRA0,Q15041,O75844,Q13546,P42858,Q9Y4C2,P31749,Q00535,P52789,Q01469,P0DP25,Q06787 16 +Regulation of extrinsic apoptotic signaling pathway in absence of ligand 0.5896090954335627 1.3582067160269808 0.1743981001225081 1.0 0.7778442734859667 10 P30154,P30153 2 +Organic hydroxy compound metabolic process 0.4127153356573168 1.3551617069119737 0.1753660420767524 1.0 0.7805531715191435 118 P37268,Q15392,Q8WTV0,P51648,O15118,P48735,Q14739,Q9BY49,P00374,Q9H4L5,Q15800,Q14914,P21964,P04062,Q16850,P48449,O75874,P07858,P35270,O15270,Q15125,P38435,Q9UBM7 23 +Protein k63 linked ubiquitination 0.5177898555618378 1.3537813595564436 0.1758061423522594 1.0 0.7819760879695704 16 Q96FW1 1 +Positive regulation of nf kappab transcription factor activity 0.4615771591142774 1.352029593606882 0.1763658484448989 1.0 0.7826940235071778 28 P19474,P02786,Q13546,P60900,P30048,P41440,O15111 7 +Negative regulation of mitochondrion organization 0.5173737286233824 1.351274867952096 0.1766073995588251 1.0 0.7826940235071778 16 P02786,O75832,P31749,P30536,Q9H3K2,O60313 6 +Associative learning 0.5828682735908907 1.350685664639828 0.1767961463005394 1.0 0.7826940235071778 11 P50897,Q00535,Q9Y639 3 +Maintenance of protein location in mitochondrion 0.8007725445169156 1.3491951223088554 0.177274301088256 1.0 0.7826940235071778 4 P31749,P30536 2 +Regulation of ion transmembrane transport 0.3970057285396159 1.3482971304862086 0.1775628346988105 1.0 0.7828194491066364 64 P62942,P08183,P21796,P78417,Q9NRA0,Q15041,O75844,P42858,Q13546,Q9Y4C2,P0CG08,Q00535,P0DP25,Q06787 14 +Chemical synaptic transmission postsynaptic 0.5657626399017934 1.3446855782792249 0.1787267938551875 1.0 0.7857882633489839 12 Q14168,Q9UQB8 2 +Regulation of postsynaptic membrane potential 0.5657626399017934 1.3446855782792249 0.1787267938551875 1.0 0.7857882633489839 12 Q14168,Q9UQB8 2 +Positive regulation of endothelial cell migration 0.4840266537522721 1.3439229988772474 0.1789732880132279 1.0 0.7858367358741735 21 Q8WTV0,P31749,P04083,P09601,O75340 5 +T cell activation 0.4027508604252651 1.3395527981629296 0.1803907783338674 1.0 0.7883537034481761 59 P62942,O96005,P78536,P17812,O15360,P31749,P04083,Q9NUQ9,P24390,P04062 10 +Neuronal action potential 0.7095163558861153 1.3391081055567104 0.1805354821339637 1.0 0.7884313523725357 5 P04062 1 +Sarcoplasmic reticulum calcium ion transport 0.6446925707514236 1.3339214605547447 0.1822295975041308 1.0 0.7914077796482164 7 P16615,P78417,O75844 3 +Endoplasmic reticulum membrane organization 0.6083199904675259 1.3336645001176923 0.1823138340550865 1.0 0.7914077796482164 8 Q15363,Q15041 2 +Autophagosome membrane docking 0.848512173128946 1.3317191296742523 0.1829525007603234 1.0 0.7923175590470084 2 O95721 1 +Calcium ion import into sarcoplasmic reticulum 0.8485121731289322 1.331719129674196 0.1829525007603418 1.0 0.7923175590470084 2 O75844 1 +Negative regulation of amyloid precursor protein catabolic process 0.5786308689482929 1.329095802415759 0.1838163649705255 1.0 0.7923175590470084 11 Q16799 1 +Post translational protein modification 0.5785789016664126 1.3288308363804011 0.1839037862343935 1.0 0.7923175590470084 11 Q32P28 1 +Connective tissue development 0.4584065052171225 1.3286756995803832 0.1839549854050077 1.0 0.7923175590470084 28 O15173,P43490,O75844 3 +Base conversion or substitution editing 0.7068340197217023 1.328046228825848 0.1841628353972821 1.0 0.7923175590470084 5 A0AV96 1 +Negative regulation of insulin secretion involved in cellular response to glucose stimulus 0.8464081755335153 1.3231058624819014 0.1858001754042586 1.0 0.7925841531269131 2 Q8N5M9 1 +Positive regulation of mrna splicing via spliceosome 0.5120638956867489 1.3192523860218095 0.18708475009931 1.0 0.7925841531269131 16 Q14011,P98179,P38159 3 +Pyrimidine nucleotide metabolic process 0.4837154941958692 1.3189273485442297 0.1871934020980796 1.0 0.7925841531269131 20 P17812,Q9H773 2 +Calmodulin dependent kinase signaling pathway 0.8813008535953583 1.317996834844957 0.1875047074684825 1.0 0.7925841531269131 3 O75844 1 +Synapse maturation 0.792209417484899 1.316072815594436 0.1881496040929988 1.0 0.7925841531269131 4 Q9UJX6 1 +Regulation of lysosomal protein catabolic process 0.7039070121758784 1.3159719697235424 0.1881834508943192 1.0 0.7925841531269131 5 P04062 1 +Regulation of protein catabolic process in the vacuole 0.7039070121758784 1.3159719697235424 0.1881834508943192 1.0 0.7925841531269131 5 P04062 1 +Neurotrophin trk receptor signaling pathway 0.6406202569391379 1.3156793686671215 0.1882816817278496 1.0 0.7925841531269131 7 Q99523,Q7L576,P42574 3 +Negative regulation of proteolysis 0.3891638824400132 1.315228717086225 0.1884330466277253 1.0 0.7925841531269131 67 P19474,P46379,Q15041,P04080,Q9BXS4,Q15392,P31749,P07858,P30086,P30048,Q96K76,Q9H2J4,Q00535,Q04323,Q9UMY4 15 +Walking behavior 0.8803367408298182 1.3144119808946044 0.1887076007851766 1.0 0.7925841531269131 3 O75844,Q8N2K0 2 +Regulation of regulated secretory pathway 0.47954134987954 1.3139461768290337 0.18886431759442 1.0 0.7925841531269131 21 Q9NRA0,P35080,Q4J6C6,P09601,Q9P253,Q00535,P16615,P0DP25,Q06787 9 +Regulation of transporter activity 0.4073084829858142 1.3134942098112738 0.1890164707305124 1.0 0.7925841531269131 51 P62942,P08183,P78417,Q9NRA0,P42858,Q13546,Q03164,Q9Y4C2,Q00535,P0DP25,Q06787 11 +Ion transport 0.4438765529217029 1.3134442196373024 0.1890333052990596 1.0 0.7925841531269131 204 P62942,P14174,O75844,Q9UBX3,P12235,Q9HD20,Q9NQ11,P07602,Q8WWC4,P00846,Q96S66,Q70HW3,Q06787,P53985,Q9Y619,P42858,O43772,Q9UDW1,P41440,P21796,P08183,P45880,P78417,Q9H2D1,Q15041,P31749,Q02790,P30536,Q9HC07,O95563,Q7KZN9,P20674,P02786,O75964,Q02978,Q96QD8,Q9H813,Q9UHG3,O15173,P04083,Q6P4A7,Q00535 42 +Regulation of immune response 0.4189609517545273 1.3126995564453552 0.1892842071416614 1.0 0.7925841531269131 135 P62942,Q7Z739,P28070,Q5KU26,P25786,Q9Y4E8,Q96FZ2,Q9Y5A9,Q9NPR9,P09601,P41440,Q96PK6,Q9NUQ9,P19474,O96028,Q8TCT8,O94992,Q9NUD5,Q9NZ08,P46379,Q7KZ85,P02786,P46108,O43657,P04083,P28482 26 +Membrane protein ectodomain proteolysis 0.575264640040138 1.3119231658728854 0.1895460602836327 1.0 0.7925841531269131 11 Q9NZ08,Q8TCT8 2 +Sulfur compound biosynthetic process 0.4159567807840499 1.3109224878086494 0.1898839524720581 1.0 0.7925841531269131 44 P50897,Q9UJ14,O43505,Q8NCH0,Q9UMR5,Q13126,Q9NZ01,O95563 8 +Regulation of plasma lipoprotein particle levels 0.5183713161510286 1.3108876858459082 0.189895711794906 1.0 0.7925841531269131 15 Q8WTV0 1 +Response to insulin 0.3945338050930782 1.308130801100619 0.190828947919744 1.0 0.79289511999273 63 Q9BSK2,P43490,Q9UQB8,Q16836,Q99523,P31749 6 +Regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway 0.5793627038771803 1.306753528441334 0.1912964326497417 1.0 0.7936632130217175 10 Q9NUD5 1 +Regulation of epithelial cell migration 0.4213041729375608 1.3051054185254745 0.1918569539461141 1.0 0.7950983145667295 42 Q15555,Q8WTV0,P42785,P31749,P04083,P09601,O75340 7 +Synaptonemal complex organization 0.6379899646890972 1.3038887309548184 0.1922715230681688 1.0 0.7957691478940947 7 Q15645,P46379,Q92791 3 +Phospholipid metabolic process 0.3802496014982354 1.3032413744842666 0.1924923688941626 1.0 0.7957691478940947 80 P37268,Q9NPH0,O75874,Q8WTV0,Q8NCC3,O15270,P42356,P35790,Q8N2K0,O95674 10 +Regulation of cellular response to growth factor stimulus 0.4394744944510488 1.3022793837498097 0.1928208966051909 1.0 0.7957691478940947 35 P62942 1 +Negative regulation of nik nf kappab signaling 0.7885714285714298 1.3020012397728011 0.1929159617922993 1.0 0.7957691478940947 4 O43657,O00571,Q9H000 3 +Negative regulation of hydrolase activity 0.3859378798059929 1.298576230445735 0.1940893996527608 1.0 0.7982653610073369 68 P62942,Q15041,Q99523,Q15392,O95429,P31749,P07858,P30086,Q15363 9 +Import across plasma membrane 0.5085653404487402 1.298114701804838 0.1942479230646046 1.0 0.7982653610073369 16 Q15041,P41440 2 +Urogenital system development 0.4072764650795912 1.297752857751013 0.1943722737809829 1.0 0.7982653610073369 48 P46379,O75844,P07602,Q02790,O95470,Q7LG56 6 +Regulation of glucose import 0.5766359240106214 1.29303328774364 0.1959995463869419 1.0 0.8015695739679713 10 P31749,Q16539,P52789 3 +Regulation of protein k63 linked ubiquitination 0.6714349228623832 1.2919315726651217 0.1963808426521469 1.0 0.8015695739679713 6 O00571,Q96FW1,O95071 3 +Insulin secretion involved in cellular response to glucose stimulus 0.5808824426855901 1.28964377272311 0.1971743702310497 1.0 0.8032364180239717 9 O95563,Q8N5M9 2 +Extracellular matrix assembly 0.6705535270299541 1.2882060192667792 0.1976742572371757 1.0 0.8038175494666367 6 Q96AY3 1 +Low density lipoprotein particle clearance 0.5548829537480271 1.2869639262835084 0.1981068618965265 1.0 0.8043458634525342 12 Q92945,P09601,Q8WTV0 3 +Cation transmembrane transport 0.4079820434522278 1.2869454616845202 0.1981132980931925 1.0 0.8043458634525342 120 P62942,P21796,P78417,Q9Y619,O75964,P12235,O43772,Q9HD20,Q9HC07,Q9UDW1,Q9NQ11,P00846,Q70HW3 13 +Behavioral response to pain 0.7843569576178289 1.285701266863719 0.1985473389458592 1.0 0.8043458634525342 4 P31749 1 +Response to pain 0.7843569576178286 1.285701266863718 0.1985473389458596 1.0 0.8043458634525342 4 P31749 1 +Type i interferon production 0.4519469541672863 1.280967726973541 0.2002050020627126 1.0 0.805490040734951 28 P19474,P41440 2 +Regulation of postsynapse organization 0.5132751519021255 1.2807742681666066 0.2002729646928895 1.0 0.805490040734951 15 P18085,Q9UQB8 2 +Positive regulation of synaptic transmission 0.4778431532118895 1.2801615432058184 0.2004883278673332 1.0 0.805490040734951 20 Q14168,P41440,P28482,Q06787,Q9Y639 5 +Regulation of syncytium formation by plasma membrane fusion 0.6677719027307574 1.2764456373486228 0.2017980322686168 1.0 0.805490040734951 6 P17655,Q14012,Q16539,P41440 4 +Positive regulation of syncytium formation by plasma membrane fusion 0.6677719027307574 1.2764456373486228 0.2017980322686168 1.0 0.805490040734951 6 P17655,Q14012,Q16539,P41440 4 +Adult behavior 0.4804373539001325 1.2764212840825513 0.2018066363221073 1.0 0.805490040734951 19 P50897,O75844,P04080,O15118,Q6Y7W6,Q8N2K0 6 +Negative regulation of mrna splicing via spliceosome 0.5046716693692195 1.2745553731537151 0.2024666616082333 1.0 0.8070594512312816 16 Q07021,P61978,P22626,Q13242,P98175,P38159,Q13247,P26368 8 +Regulation of stem cell differentiation 0.4794155788130044 1.2697587136565402 0.2041705913670086 1.0 0.8081597610239497 19 Q96PZ0,Q9Y5A9,Q9Y6C9,Q08J23 4 +Cell volume homeostasis 0.7801503759398509 1.2694343358379474 0.2042861964499553 1.0 0.8081597610239497 4 P54105,P51790,Q96ER9 3 +Ribonucleoside metabolic process 0.5767954307178489 1.2693582528637677 0.2043133185713279 1.0 0.8081597610239497 9 O60725,Q13126 2 +Negative regulation of intrinsic apoptotic signaling pathway 0.4351865331630639 1.267951914171701 0.2048151231563253 1.0 0.8081597610239497 35 P14174,O00571,P45880,Q9UL15,P31749,P16989,Q96K76,O95881,Q8N2F6,P10909,Q7LG56,O60313 12 +Negative regulation of receptor binding 0.8328824767057399 1.2678143582262789 0.2048642534357911 1.0 0.8081597610239497 2 P16615 1 +Regulation of protein folding 0.7795488721804525 1.2671085798712562 0.2051164681122721 1.0 0.8081597610239497 4 O14737,Q9UL15,Q9H2J4 3 +Cell adhesion molecule production 0.7794846542200681 1.266860281195722 0.2052052529805914 1.0 0.8081597610239497 4 Q5KU26,P41440 2 +Regulation of protein secretion 0.403878080900514 1.266276122595874 0.2054142424096376 1.0 0.8081919467826993 48 Q8N183,Q9H4A6,P53985,Q16850,Q92614,Q32P28,Q16836,Q9NQ11,Q8N5M9,P00367,O95563 11 +Cellular response to reactive nitrogen species 0.6291676316781768 1.2642990042987798 0.2061227268476391 1.0 0.8087981801501923 7 P46108,O95831 2 +Positive regulation of cell junction assembly 0.5705465718548759 1.2623552587654348 0.2068209809629189 1.0 0.8106377854020633 10 P41440 1 +Response to molecule of bacterial origin 0.419002029117851 1.2609572197917889 0.2073242607554573 1.0 0.811684346442116 41 P14174,O43823,P17655,P78536,Q9Y263,Q8WTV0,P31749,P30048,P30536,Q9NZZ3,Q16539,P28482,P08670,P42574,Q9NUQ9 15 +Cardiac muscle tissue development 0.4490714945697118 1.2596769904767229 0.2077859091626914 1.0 0.8116936555890113 28 P62942,O75844 2 +Leukotriene biosynthetic process 0.7774437120841394 1.258969464134569 0.2080413615460341 1.0 0.8116936555890113 4 Q9UJ14 1 +Lipophagy 0.6899310361887392 1.258282514734291 0.2082896024358294 1.0 0.8116936555890113 5 O15270 1 +Regulation of insulin secretion involved in cellular response to glucose stimulus 0.5914676421298192 1.2532584292165456 0.2101116719775073 1.0 0.8116936555890113 8 O95563,Q8N5M9 2 +Skeletal system development 0.4023816781637193 1.2523915784185984 0.2104272135032128 1.0 0.8116936555890113 48 Q15125,O95470,Q7RTS9,Q32P28 4 +Response to manganese ion 0.6883454449098709 1.2517349226642571 0.2106664702862173 1.0 0.8116936555890113 5 Q9NQ11,P30536 2 +Lipid biosynthetic process 0.4198251841621653 1.251705349697091 0.2106772500178513 1.0 0.8116936555890113 147 P14174,Q16739,P37268,Q99805,Q86YN1,Q9NPH0,Q9P035,Q15392,Q8WTV0,Q06136,Q14739,Q9BY49,P35790,Q96G23,Q9H4L5,Q15800,Q13510,P04062,Q16850,P48449,O75874,Q9Y2B2,P31749,P30536,Q8NCC3,Q9NZ01,P49327,O95470,P42356,O15270,Q8NBX0,Q15125,Q9UBM7,P04083,Q01469,O95674 36 +Pyridine containing compound catabolic process 0.8632913291724731 1.2510928861337467 0.210900590678549 1.0 0.8116936555890113 3 Q13126 1 +Regulation of synapse structure or activity 0.4422221481132389 1.250861359697652 0.2109850635833237 1.0 0.8116936555890113 31 P50897,Q9UQB8,P18085,Q9UJX6,Q00535,O00264 6 +Negative regulation of voltage gated calcium channel activity 0.8286744815148801 1.250645395373729 0.2110638806747613 1.0 0.8116936555890113 2 Q06787 1 +Maintenance of protein location in cell 0.4590773105342948 1.2498035752262655 0.2113713097533773 1.0 0.8116936555890113 24 Q9H4A6,O94901,P31749,O43731,P30536,Q00535,P52789,P36404,P24390 9 +Response to arsenic containing substance 0.5318551594953771 1.2494261504336348 0.211509248720763 1.0 0.8116936555890113 13 P78417,Q9BWF3,Q96QD8,P07196,P09601,P09651 6 +Atp transport 0.6610029647669063 1.2478114037865002 0.2121001314862194 1.0 0.8116936555890113 6 P12235,Q6NUK1,P05141 3 +Cellular response to oxygen levels 0.4325427975018953 1.246742876476214 0.2124917919010076 1.0 0.8116936555890113 35 Q8N511,O95831,O75306,P31749,P55786,P09601,Q9Y487,Q15120,Q96A26 9 +Dendrite self avoidance 0.8620328028438581 1.2464233890620466 0.2126089989214838 1.0 0.8116936555890113 3 Q9Y639 1 +Nitrogen compound transport 0.3196239495657322 1.2452849266149535 0.2130270343918603 1.0 0.8116936555890113 596 Q8N183,Q9NS69,O43731,A6NIH7,P24390,Q99595,Q32P28,Q9Y619,O43772,Q8N4Q1,P41440,O60725,Q9BSK2,Q9H2D1,Q15629,P10619,Q8N4H5,O95563,Q9Y282,P46379,O95831,Q03518,O15173,Q15363,Q14168,P43307,Q5JRX3,P50897,Q16836,Q99523,Q9HD20,P07602,Q9UMY4,Q14108,O95373,O43752,Q16850,Q15070,Q15041,P22626,P31749,P30536,P49257,Q9P2W9,Q7KZ85,O95391,O14925,P55786,Q9BTX1,Q96JB2,O95140,Q92614,P12235,Q9NQ11,P53365,Q9P253,Q92973,O43823,Q86YV9,Q96L92,P18085,Q4J6C6,O95721,P67809,Q9HAV4,Q9BVK6,P84085,P51991,O15027,Q96QD8,P20645,O95429,O14737,P04083,Q6P4A7,Q8N5M9,Q92945,O15397,Q8WWC4,Q06787,Q9Y6Y8,P53985,Q92783,Q9Y5X3,P08183,Q96PC5,Q08J23,O95613,O95071,Q9BUN8,P09651,P09132,O75340,Q9Y512,P02786,Q9Y2T2,Q86W42,Q00535,P61020,Q9Y5M8 100 +Regulation of phospholipase activity 0.5621269095175343 1.2447341653387505 0.2132294829315499 1.0 0.8116936555890113 11 P50897,P18085,P40616,Q9Y263,P20248,P04083 6 +Dephosphorylation 0.3899490145487743 1.243905314320919 0.2135344132484915 1.0 0.8116936555890113 99 P62942,Q969T7,P30154,Q9NPH0,Q86XL3,Q9H0P0,P30153 7 +T cell mediated cytotoxicity 0.6245543279358403 1.2435738551176423 0.2136564435403181 1.0 0.8116936555890113 7 P01889,P04439,Q9NUQ9,O15400 4 +Positive regulation of mitophagy 0.8604454173361875 1.240535041537157 0.2147775615378744 1.0 0.8139644447970505 3 P21796 1 +Mitochondrial fission 0.5132107906415466 1.2383288409133602 0.215594153983567 1.0 0.8152150761452069 14 Q9UDX5,Q9NUQ9,O60313 3 +Negative regulation of cell killing 0.7720211579902461 1.2380097883008994 0.2157124314225187 1.0 0.8152150761452069 4 P46108,P04439 2 +Phosphatidylethanolamine metabolic process 0.7716304309333248 1.2364998661595503 0.2162728154491171 1.0 0.8152150761452069 4 Q8NCC3 1 +Calcium import into the mitochondrion 0.6582162358539395 1.2360171873432149 0.2164521750144574 1.0 0.8152150761452069 6 P21796 1 +Negative regulation of establishment of protein localization to mitochondrion 0.7712769608294782 1.2351339638763963 0.2167806508937249 1.0 0.8152150761452069 4 P49257,O95429 2 +Necroptotic signaling pathway 0.8247670574090753 1.2347190566677388 0.2169350810312655 1.0 0.8152641297552307 2 P49327 1 +Pteridine containing compound biosynthetic process 0.569516354437148 1.2331771484936864 0.2175096790748134 1.0 0.816006849169173 9 P00374 1 +One carbon metabolic process 0.528816341883463 1.232554754903972 0.2177419262237609 1.0 0.8161232690458703 13 P00374,P34896 2 +Signal transduction in absence of ligand 0.4977083208921202 1.2323373775806783 0.2178230829077034 1.0 0.8161232690458703 16 P30154,P31749,P30153 3 +Protein geranylgeranylation 0.7700012366309739 1.230204589347773 0.2186205017465456 1.0 0.8169513934926986 4 P53609 1 +Stress granule assembly 0.4700256734751117 1.2284011877703307 0.2192964022266919 1.0 0.8184237784763428 20 Q7Z739,Q14157,Q14011,Q9BYJ9,Q9Y5A9 5 +Positive regulation of ion transport 0.4066762806717035 1.228087301366978 0.2194141974633989 1.0 0.8184237784763428 44 P14174,P08183,P78417,Q9NRA0,Q15041,P42858,Q9Y4C2,P31749,P30536,Q99996,O76024,Q00535,P0DP25,P55011 14 +Perk mediated unfolded protein response 0.6822328932085556 1.226491326693253 0.2200138372265789 1.0 0.8192487723333738 5 Q15363 1 +Regulation of protein binding 0.3964233098749603 1.2229412237953228 0.2213518968480565 1.0 0.8193295160697965 53 P62942,P19474,P31749,P41440 4 +Regulation of t cell mediated cytotoxicity 0.7678195488721821 1.221775981698714 0.2217923537277455 1.0 0.8193295160697965 4 P01889,Q9NUQ9,P04439 3 +Positive regulation of t cell mediated cytotoxicity 0.7678195488721821 1.221775981698714 0.2217923537277455 1.0 0.8193295160697965 4 P01889,Q9NUQ9,P04439 3 +Regulation of cation transmembrane transport 0.3975872906579727 1.2216553430684582 0.2218379904916656 1.0 0.8193295160697965 51 P62942,P21796,P78417 3 +Neuron death 0.3713301973089885 1.2212205537049603 0.2220025241258316 1.0 0.8193295160697965 78 P50897,Q99720,Q9NR28,Q9UMX5,O95831,Q15392,Q01105,Q9NQ11,P31749,P07196,P09601,Q96A26,P04062 13 +Hindbrain morphogenesis 0.566971745465901 1.2205145131366206 0.2222698912173011 1.0 0.8193295160697965 9 O15228,Q15058,Q00535,P04062 4 +Negative regulation of exocytosis 0.6194216718564503 1.220499595241633 0.2222755428891898 1.0 0.8193295160697965 7 P04083,P09601 2 +Cellular response to acid chemical 0.5026559140415108 1.2178476875079098 0.2232818586364213 1.0 0.8193295160697965 15 Q9UQB8,Q8IWV7,Q9Y2Q5,Q14103,Q99729 5 +Lymphocyte activation 0.387356964890435 1.214363046853808 0.224609119986932 1.0 0.8193295160697965 99 P62942,P14174,Q9UQ84,Q96L92,P46379,O96005,Q7KZ85,O96028,P78536,P17812,P31749,O15360,P04083,Q96FZ2,Q9NUQ9,P24390,P04062 17 +Early endosome to golgi transport 0.6792362287720092 1.214115279171126 0.2247037062088555 1.0 0.8193295160697965 5 P49257 1 +Regulation of anion transmembrane transport 0.617595488144879 1.2122862623085229 0.2254028207030756 1.0 0.819577781436603 7 P08183,Q13546,Q15041 3 +Cytoplasmic pattern recognition receptor signaling pathway in response to virus 0.5011064222559066 1.2086474735686357 0.2267983095019199 1.0 0.8223496493051189 15 Q9NUD5 1 +Nerve development 0.6166812022346425 1.2081735845586434 0.2269805001738105 1.0 0.8225509866789765 7 P42892 1 +Immune response regulating signaling pathway 0.3883370969718129 1.206666020984543 0.2275607898962321 1.0 0.8239307483692775 60 Q9NPR9,P46379,Q9NUD5,P41440 4 +Regulation of tube size 0.5544883100294158 1.2055596189972244 0.2279873371605503 1.0 0.8239307483692775 11 Q9HB40 1 +Protein localization to chromosome centromeric region 0.5238320176025553 1.204850135073187 0.2282611615803178 1.0 0.8239307483692775 13 Q96DY7,Q9H900 2 +Extrinsic apoptotic signaling pathway 0.4123482940796142 1.2035672760909923 0.2287568739312915 1.0 0.8239307483692775 41 Q9NR28,P30154,P42858,Q99523,P31749,P30153,P09601 7 +Positive regulation of cell killing 0.6144490577572111 1.1981311836226929 0.2308659506163783 1.0 0.8278038989095908 7 P01889,Q9NUQ9,P04439 3 +Lipid droplet formation 0.761506312609652 1.1973971472855252 0.2311517950407704 1.0 0.8278038989095908 4 O95674 1 +Inflammatory response to antigenic stimulus 0.5615463926861897 1.1934939539666367 0.2326759786146277 1.0 0.8278038989095908 9 Q9H000,P25786,P28070 3 +Phosphatidylcholine biosynthetic process 0.6134134243927315 1.1934711167968008 0.232684917383152 1.0 0.8278038989095908 7 Q01469,P35790 2 +Positive regulation of dendritic spine development 0.5568234715142305 1.193045373110436 0.2328516036695096 1.0 0.8278038989095908 10 Q9UQB8 1 +Granulocyte differentiation 0.6130663877653992 1.1919094451517336 0.2332967542753659 1.0 0.8278038989095908 7 P49327,Q14739 2 +Response to l glutamate 0.6736196689006997 1.190920628467737 0.2336847455025477 1.0 0.8278038989095908 5 Q9UQB8 1 +Chaperone mediated autophagy 0.5563948639021684 1.1908772491556645 0.2337017771146596 1.0 0.8278038989095908 10 P08621,Q9NQ11,P10909,P10619 4 +Response to axon injury 0.4754388107960723 1.1904686477130866 0.233862245641375 1.0 0.8278038989095908 18 P00374,P30536,Q96G23,P11047 4 +Negative regulation of defense response 0.4230305104952944 1.1902366782632412 0.2339533808851401 1.0 0.8278038989095908 36 Q7Z739,P19474,P28070,Q9H000,P25786,Q9Y3Z3,P46108,O43657,Q9Y4E8,Q16539,P04439,P01889,Q9Y5A9,P04062 14 +Reproductive system development 0.3707755872987431 1.1901003532075167 0.2340069514765259 1.0 0.8278038989095908 71 P62993,Q15392,O75874,P07602,P31749,P16989,Q02790,P07858,P04083,Q15363,P28482,O95470,P35613 13 +Regulation of gtp binding 0.6123767615778184 1.1888059673510516 0.2345160292928181 1.0 0.8278038989095908 7 O75503 1 +Response to oxygen levels 0.3816048116932624 1.1885158594852576 0.2346302353196394 1.0 0.8278038989095908 64 Q8N511,O95831,P30519,O75306,P31749,P55786,P09601,Q9Y487,P00846,Q15120,Q96A26 11 +Mitochondrial ribosome assembly 0.6468901480037663 1.1880574822383287 0.2348107638039636 1.0 0.8278038989095908 6 Q567V2 1 +Detection of stimulus 0.4660550857522806 1.1823927681406388 0.2370498913796368 1.0 0.8278038989095908 19 Q15555,Q8WTV0,P30536,P04439,P0DP25 5 +Protein destabilization 0.5351999616236074 1.1820536606411016 0.2371844096393571 1.0 0.8278038989095908 12 P42858,P19474,P54725 3 +Histone h3 k4 demethylation 0.7570328512835887 1.1801346940597364 0.2379466478058627 1.0 0.8278038989095908 4 Q9H6W3 1 +Myeloid leukocyte cytokine production 0.5759770873160246 1.1791018209535848 0.2383576336081088 1.0 0.8278038989095908 8 P09601 1 +Respiratory chain complex iv assembly 0.6097173798930251 1.1768364263761493 0.2392608004778669 1.0 0.8278038989095908 7 O75880,Q15070,Q9Y2R0 3 +Protection from natural killer cell mediated cytotoxicity 0.8103396453261168 1.1760713510050298 0.2395663650537396 1.0 0.8278038989095908 2 P04439 1 +Detection of other organism 0.8103396453261168 1.1760713510050298 0.2395663650537396 1.0 0.8278038989095908 2 P04439 1 +Glycosphingolipid biosynthetic process 0.8427671945203397 1.1750752849808828 0.239964597509644 1.0 0.8278038989095908 3 Q16739 1 +Microglial cell proliferation 0.8100390742410427 1.174852465626074 0.2400537456932094 1.0 0.8278038989095908 2 P04062 1 +Digestion 0.4951148573466629 1.173032667981361 0.2407827055862736 1.0 0.8278038989095908 15 Q16739,O00625,Q8WTV0 3 +Formation of extrachromosomal circular dna 0.6430390873196415 1.171744609753097 0.2412996070308515 1.0 0.8278038989095908 6 Q9UQ84 1 +Protein oxidation 0.8418520745640294 1.171693498125203 0.2413201343758526 1.0 0.8278038989095908 3 P30048,Q8N4Q1 2 +Crd mediated mrna stabilization 0.5570293017273297 1.170975702961029 0.241608543638947 1.0 0.8278038989095908 9 P67809,Q14103,O60506 3 +Negative regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay 0.5570293017273297 1.170975702961029 0.241608543638947 1.0 0.8278038989095908 9 P67809,Q14103,O60506 3 +Retinal rod cell development 0.8088367899008095 1.1699782371559184 0.2420097269114518 1.0 0.8278038989095908 2 Q15555 1 +Camera type eye photoreceptor cell differentiation 0.8088367899008095 1.1699782371559184 0.2420097269114518 1.0 0.8278038989095908 2 Q15555 1 +Retinal rod cell differentiation 0.8088367899008095 1.1699782371559184 0.2420097269114518 1.0 0.8278038989095908 2 Q15555 1 +Cellular response to xenobiotic stimulus 0.4352875183892765 1.169531533275323 0.2421895442087218 1.0 0.8278038989095908 29 Q96DG6,O15217,P07099,O43169 4 +Negative regulation of lipase activity 0.8407645638169964 1.167675633172921 0.2429376292179577 1.0 0.8278038989095908 3 Q99523 1 +Dna methylation involved in gamete generation 0.8082356477306746 1.1675419199159287 0.2429915896562611 1.0 0.8278038989095908 2 Q8NB78 1 +Nucleoside triphosphate metabolic process 0.3918839504072414 1.1674815601135653 0.2430159508190557 1.0 0.8278038989095908 51 Q9H773,O75964,P17812,P00846,Q7LG56 5 +Release of cytochrome c from mitochondria 0.4714613689225481 1.1650485942775812 0.2439993232516148 1.0 0.8278038989095908 18 O75832,P31749,O14737,Q9H3K2,Q9Y3D6,P10909,Q96A26,O60313 8 +Positive regulation of organic acid transport 0.6412490488355869 1.1641616624126958 0.2443585034725401 1.0 0.8278038989095908 6 Q15041 1 +Tricarboxylic acid metabolic process 0.5510443810169984 1.1637968314489018 0.2445063565320024 1.0 0.8278038989095908 10 P48735 1 +Mitochondrial calcium ion transmembrane transport 0.5550416180660125 1.1610613936088006 0.2456169333618638 1.0 0.8278038989095908 9 P21796 1 +Centromeric sister chromatid cohesion 0.6060274002781468 1.1602244043080558 0.2459574534008757 1.0 0.8278038989095908 7 P30153,O60566,O43683 3 +Protein o linked glycosylation 0.4924548305190983 1.1572023454499023 0.2471896997149565 1.0 0.8278038989095908 15 O60502 1 +Response to acid chemical 0.4456259260377787 1.1549316842943034 0.2481184032583856 1.0 0.8279963570195048 24 Q9UQB8,O95831,Q8IWV7,Q9Y2Q5,Q14103,Q99729 6 +Proton transporting two sector atpase complex assembly 0.7486705155672033 1.1478984709137523 0.2510104795236607 1.0 0.8334602668583803 4 Q15070 1 +Purine ribonucleoside metabolic process 0.5694091826726486 1.1476083837277653 0.2511302672468209 1.0 0.8334602668583803 8 O60725 1 +Metal ion transport 0.3836899846229657 1.1473974083245182 0.2512174118421351 1.0 0.8334602668583803 102 P62942,P21796,P78417,O75844,P02786,P42858,Q96QD8,Q9HD20,P31749,O15173,Q02790,P30536,Q00535,Q8WWC4,P16615,Q9HC07,Q06787 17 +Meiotic chromosome segregation 0.4480425580777217 1.1467054506932717 0.2515033769748793 1.0 0.8334602668583803 23 O94901,P46379,Q92791,O43683,P30153,O60566,Q9BTX1,Q15645 8 +3 utr mediated mrna destabilization 0.6369357215418883 1.1458892977472186 0.2518409600377653 1.0 0.8334602668583803 6 Q92945,Q9HCE1,Q14103 3 +Regulation of organic acid transport 0.5474342016587479 1.1455104287757074 0.251997777894644 1.0 0.8334602668583803 10 P31749,Q15041 2 +Positive regulation of neurotrophin trk receptor signaling pathway 0.8022242260294545 1.143209237643564 0.2529517277934827 1.0 0.8334602668583803 2 Q7L576 1 +Regulation of neurotrophin trk receptor signaling pathway 0.8022242260294545 1.143209237643564 0.2529517277934827 1.0 0.8334602668583803 2 Q7L576 1 +Protein localization to condensed chromosome 0.5279301025008865 1.1431789423319476 0.2529643033535367 1.0 0.8334602668583803 12 Q96DY7,Q9H900 2 +Protein targeting 0.3947263107014629 1.1418902542595466 0.2534996401077789 1.0 0.8335324875240083 119 Q99595,P46379,Q15041,O95831,Q15629,Q99523,Q9NS69,Q5JRX3,Q8N4Q1,O14925,P30536,P55786,O60725,P43307,Q8N4H5,Q14108,P49257 17 +Meiotic sister chromatid cohesion centromeric 0.8328322309079879 1.1384036414982035 0.2549519741946748 1.0 0.835802179771107 3 P30153,O60566 2 +Meiosis ii cell cycle process 0.8328322309079879 1.1384036414982035 0.2549519741946748 1.0 0.835802179771107 3 P30153,O60566 2 +Positive regulation of type i interferon production 0.4534329760094268 1.1382873642195603 0.2550005085098681 1.0 0.835802179771107 21 P41440 1 +Negative regulation of fatty acid transport 0.8007213706041322 1.1371351091126325 0.255481808857386 1.0 0.8359575553217926 2 P31749 1 +Regulation of actin cytoskeleton reorganization 0.5502073270858993 1.1369362893233843 0.2555649203000545 1.0 0.8359575553217926 9 Q13576,Q9UQB8 2 +Selective autophagy 0.4273786258271219 1.1367252199866664 0.2556531729086972 1.0 0.8359575553217926 31 P21796,P42858,P12235,P53365,O95140,O15270 6 +Positive regulation of epithelial cell migration 0.4291118111258075 1.135939197421962 0.2559820120539091 1.0 0.8363308579341833 30 Q15555,Q8WTV0,P31749,P04083,P09601,O75340 6 +Chemokine production 0.5663583636029371 1.132972112542243 0.2572259646466897 1.0 0.8373059721381467 8 P14174,P09601,P78536 3 +Lymphocyte apoptotic process 0.4882081324884612 1.1319079919114416 0.2576731183823004 1.0 0.8383412979832962 15 P14174,P31749,P24390 3 +Negative regulation of lymphocyte mediated immunity 0.7438549035991702 1.1293575401078582 0.2587470367853184 1.0 0.8391059808032192 4 P46108,P04439 2 +Pyrimidine nucleoside metabolic process 0.6586022592624293 1.128936383766964 0.2589246709781712 1.0 0.8391059808032192 5 Q9H0P0 1 +Phosphate ion transmembrane transport 0.8294855558477282 1.126073255311178 0.2601345133423989 1.0 0.8391059808032192 3 Q02978 1 +Phosphate ion transport 0.8294855558477282 1.126073255311178 0.2601345133423989 1.0 0.8391059808032192 3 Q02978 1 +Protein localization to endoplasmic reticulum 0.4175339518445293 1.125742530922855 0.2602745157642683 1.0 0.8391059808032192 35 Q15629,O43731,P24390 3 +Regulation of amyloid beta clearance 0.598115906000759 1.1245971382708162 0.2607597869440736 1.0 0.8391059808032192 7 Q16850,P15260 2 +Photoreceptor cell maintenance 0.7974150886684648 1.1237854857139982 0.2611040403270035 1.0 0.8391059808032192 2 Q15555 1 +Protein localization to phagophore assembly site 0.5643981918994484 1.1235662185708273 0.2611970939348738 1.0 0.8391059808032192 8 P53365,Q7Z3C6,O95140 3 +Mitochondrial cytochrome c oxidase assembly 0.6316648070322186 1.123561820918924 0.2611989604653257 1.0 0.8391059808032192 6 Q15070,Q9Y2R0 2 +Aerobic respiration 0.3732829038960025 1.122760276703767 0.2615393203082936 1.0 0.8391059808032192 91 Q9BSK2,O43676,Q15070,P20674,O75964,O75874,Q9UDW1,O75306,P34897,O75438,Q9H3K2,P48735,P00846,P14406,O14949 15 +Carbohydrate homeostasis 0.3889603679204386 1.122010372461328 0.2618580297244977 1.0 0.8391059808032192 46 P53985,P62995,P42785,P31749,P52789,Q8N5M9,Q01469,Q15120,O95563 9 +Leukocyte homeostasis 0.5089264181439929 1.1217976048783007 0.2619485048338785 1.0 0.8391059808032192 13 P14174,P78536,P31749,P04083,P49327 5 +Male meiotic nuclear division 0.7415134763404141 1.120349540963747 0.2625648384513288 1.0 0.8391059808032192 4 O15360,Q15645 2 +Extrinsic apoptotic signaling pathway via death domain receptors 0.4790517424462097 1.1187664631456318 0.2632397825233263 1.0 0.8391059808032192 16 P09601,Q9NR28 2 +Positive regulation of anion transmembrane transport 0.740718492362824 1.1172921507995603 0.2638694304762947 1.0 0.8391059808032192 4 P08183,Q15041 2 +Plasma membrane to endosome transport 0.6557264230302082 1.11707607660656 0.2639617984497282 1.0 0.8391059808032192 5 Q99523,P61020 2 +Anatomical structure maturation 0.4283285013311053 1.11703083956078 0.2639811393256817 1.0 0.8391059808032192 29 Q15125,Q08J23,Q15645,P04818,Q9Y2W6,P30153,O75503,O60341,Q9Y5A9,Q15058,P04062 11 +Regulation of autophagy of mitochondrion in response to mitochondrial depolarization 0.6291861841802374 1.113063828843078 0.2656810171346446 1.0 0.8419180434632636 6 O95140,P52789,P04062 3 +Cellular response to arsenic containing substance 0.5452760769085189 1.112312004000927 0.2660040244035868 1.0 0.8422379982822491 9 Q96QD8,P78417,P09601 3 +Monocyte differentiation 0.5952454206130511 1.1116689894233995 0.2662804978036792 1.0 0.8425890173811442 7 O00625 1 +Demethylation 0.4494658744357162 1.1114507348199538 0.2663743844600383 1.0 0.8425890173811442 21 Q9H6W3,Q9NRW3,Q16850,Q8NB78 4 +Negative regulation of cytokine production 0.4256760320852129 1.1097033161868162 0.2671268934350044 1.0 0.8441469810057998 30 O43823,P04062,P30536,P09601,Q9Y639 5 +Glutathione catabolic process 0.7938082356477114 1.1092442780202794 0.2673248160170081 1.0 0.8443615540926315 2 Q9UJ14 1 +Activation induced cell death of t cells 0.6537015117197466 1.1087276850104113 0.2675476749638255 1.0 0.8446546432742259 5 P49327,P31749 2 +Regulation of cell migration involved in sprouting angiogenesis 0.7377678562207013 1.1059495162508977 0.2687483708849023 1.0 0.8447492354920405 4 P09601 1 +Response to dsrna 0.4693628465952826 1.1035633923484187 0.269782578494887 1.0 0.845468283821668 17 P28482,Q5KU26,P41440,Q9NUD5 4 +Negative regulation of amyloid beta clearance 0.8233658318058752 1.103559051164915 0.2697844625604397 1.0 0.845468283821668 3 Q16850 1 +Cerebellar purkinje cell layer development 0.593405206720468 1.1033809740344418 0.2698617554825109 1.0 0.845468283821668 7 P04062,Q15058,P54802,O14949 4 +Developmental maturation 0.4032133832078682 1.103119123703442 0.269975437064246 1.0 0.845468283821668 40 P51790,Q15125,Q08J23,Q15645,O60341,P04818,Q9Y2W6,P30153,Q9UJX6,P07196,O75503,Q9Y5A9,Q15058,P04062 14 +Meiotic cell cycle checkpoint signaling 0.7368403807112451 1.1023858874440082 0.2702939442628493 1.0 0.845468283821668 4 Q08J23 1 +T cell apoptotic process 0.5341301962145393 1.1008562654977627 0.2709592189774472 1.0 0.8460902870825485 11 P31749,P24390 2 +Acetyl coa biosynthetic process 0.5427834742561322 1.09986036173652 0.2713929675648514 1.0 0.8460902870825485 9 O95563 1 +Negative regulation of cell matrix adhesion 0.6252165781216268 1.0962538999842155 0.2729676776701764 1.0 0.8462808603981502 6 Q9ULV4,O14936,P42771 3 +Pyridine nucleotide metabolic process 0.7351926293723677 1.0960568497880785 0.2730538965212528 1.0 0.8462808603981502 4 P43490 1 +Regulation of membrane potential 0.3783363181295861 1.094956777688515 0.2735355727046828 1.0 0.8462808603981502 59 Q9BSK2,O75844,Q9UQB8,P31749,P30048,P30536,Q8N0X7,Q00535,Q14168,P16615,Q06787,P04062 12 +Regulation of inflammatory response to antigenic stimulus 0.5912159461813369 1.0935211480122229 0.2741650489022704 1.0 0.8462808603981502 7 Q9H000,P25786,P28070 3 +Positive regulation of epithelial cell proliferation 0.4265999014933581 1.0922936835398942 0.2747040358020673 1.0 0.8462808603981502 28 P78536,P11047,Q92766,P31749,P09601,Q9H2J4,O75340,P15291 8 +Acute inflammatory response 0.733758019331544 1.0905487414351902 0.2754714949083647 1.0 0.8470226742116101 4 P42785,P02786 2 +Regulation of post translational protein modification 0.818964472912034 1.0873951658948695 0.2768622066601172 1.0 0.8492259048284929 3 Q32P28 1 +Mitochondrial dna replication 0.5399376867167768 1.085641266938602 0.2776377348378367 1.0 0.8493340359346999 9 P51530,Q7LG56 2 +Glycosylceramide catabolic process 0.8176564455573547 1.0825963572017725 0.2789876249265712 1.0 0.8515267296935245 3 P04062 1 +Negative regulation of immune system process 0.3824418976170718 1.082379779126541 0.2790838095539063 1.0 0.8515267296935245 52 Q7Z739,P14174,P28070,P19474,P25786,Q9H000,Q9Y3Z3,P46108,P31749,P04083,Q9Y4E8,P09601,Q9HCL2,P04439,P01889,Q9Y5A9,P42574 17 +Lipid droplet organization 0.5389937265308047 1.0809241094459223 0.279730873117586 1.0 0.8515861447653571 9 Q8N0X7,O95674 2 +Regulation of action potential 0.5345955814948248 1.0804090103663355 0.2799600852259063 1.0 0.8515861447653571 10 P16615,P0DP25,Q06787,P04062 4 +Cerebellar cortex development 0.501229934151924 1.07882186832676 0.2806671442408521 1.0 0.8515861447653571 13 P04062,Q5KU26,O94992,Q00535,Q15058,P54802,O14949 7 +Macromolecule deacylation 0.4047399262801735 1.077492129747767 0.2812604649316712 1.0 0.8515861447653571 38 P50897,O43823,Q9NUJ1,Q9UMR5,Q8N2K0 5 +Phagocytosis recognition 0.7302026380073934 1.0769074989740008 0.281521592595616 1.0 0.8515861447653571 4 Q92614,Q8WTV0 2 +Positive regulation of actin cytoskeleton reorganization 0.7301176175250609 1.0765814641170086 0.2816672887920988 1.0 0.8515861447653571 4 Q9UQB8 1 +Regulation of skeletal muscle cell differentiation 0.729924812030077 1.075842127728543 0.2819978678202419 1.0 0.8515861447653571 4 Q9BYT8,Q9BRT2,Q92841 3 +Signal release 0.3770972913082338 1.0729534694829064 0.2832919937449381 1.0 0.8527606350631922 58 P14174,Q8N183,P50897,P53985,Q16836,P16615,Q4J6C6,P04083,Q00535,Q9P253,Q8N5M9,P0DP25,O95721,Q06787,O95563 15 +Regulation of blood circulation 0.4304010850173901 1.072469010662524 0.2835094257932602 1.0 0.8527606350631922 25 P42892,P78417,O75844 3 +Regulation of chaperone mediated autophagy 0.7287607710622835 1.0713793711636788 0.2839988845021224 1.0 0.8531630010349869 4 P10619 1 +Heparan sulfate proteoglycan metabolic process 0.6179644916932688 1.0655576901235178 0.2866236338511951 1.0 0.8562322973166584 6 O43909,Q99805 2 +Heparan sulfate proteoglycan biosynthetic process 0.6179644916932688 1.0655576901235178 0.2866236338511951 1.0 0.8562322973166584 6 O43909,Q99805 2 +Glycerol 3 phosphate metabolic process 0.7826871055004474 1.064566791975302 0.2870720140885228 1.0 0.8562332159079664 2 P43304 1 +Import into cell 0.4424539885871353 1.0639465113212887 0.2873529311813758 1.0 0.8562332159079664 21 Q15041,P41440 2 +Synaptic membrane adhesion 0.7823865344153902 1.0633628412941274 0.2876174371495854 1.0 0.8562332159079664 2 P10586 1 +Negative regulation of protein maturation 0.6168203193422274 1.0607168295469642 0.2888186093142768 1.0 0.8562332159079664 6 Q9BXS4 1 +Regulation of multicellular organism growth 0.512422141814999 1.060099075011096 0.2890995285818687 1.0 0.8562332159079664 12 O95470 1 +Multicellular organism aging 0.526147790462574 1.0597231139917165 0.2892705841305962 1.0 0.8562332159079664 11 O75844 1 +Regulation of ion transport 0.3637137334546407 1.058422541750978 0.2898628470520339 1.0 0.8562332159079664 86 P62942,P21796,P14174,P78417,Q15041,O75844,P31749,P30536 8 +Vascular associated smooth muscle cell proliferation 0.5257497153494487 1.0576711884638843 0.290205374922893 1.0 0.8562332159079664 11 P09601,O95140,P09493 3 +Neuron recognition 0.5831278143293599 1.057101157759434 0.2904654228934773 1.0 0.8562332159079664 7 Q9Y639,P35613 2 +Myeloid leukocyte differentiation 0.4232734451046938 1.0570520355264672 0.290487839788665 1.0 0.8562332159079664 27 P49327,Q14739,O00625,P04062 4 +Antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway 0.8105832832230833 1.056688171025116 0.2906539253341229 1.0 0.8562332159079664 3 P04439,P10321 2 +Negative regulation of natural killer cell mediated immunity 0.8105832832230817 1.05668817102511 0.2906539253341256 1.0 0.8562332159079664 3 P46108,P04439 2 +Glycolipid catabolic process 0.5828415295215121 1.0558123585825758 0.2910539508366629 1.0 0.8562332159079664 7 P17900,P04062 2 +O glycan processing 0.6403076656302839 1.0535759316200717 0.2920771133022244 1.0 0.856582044086465 5 O43505 1 +Monocarboxylic acid transport 0.5292892317490909 1.05348035827414 0.2921208917591005 1.0 0.856582044086465 10 P14174,P04083,O95563 3 +Cellular iron ion homeostasis 0.4963825814632697 1.051733533152582 0.2929218214551441 1.0 0.8573135116721156 13 Q8N511,Q9NQ11,P09601,Q9Y487 4 +Regulation of myeloid cell apoptotic process 0.6146241638002509 1.0514271009191325 0.2930624742912577 1.0 0.8573135116721156 6 P14174,P04083,P78536 3 +Carbohydrate transmembrane transport 0.4747148123891775 1.051397486859089 0.2930760695891741 1.0 0.8573135116721156 15 Q99523,P31749,Q16539,P52789,Q01469 5 +Muscle tissue development 0.3791869785753585 1.051007191872312 0.2932552867569806 1.0 0.8574515228274796 52 P62942,O75844,P09493,P16989,P41440 5 +Positive regulation of rig i signaling pathway 0.7233562602025969 1.050680469154685 0.293405369103852 1.0 0.8575042605582428 4 Q9NUD5 1 +Glycerophospholipid biosynthetic process 0.3968622789470527 1.0484357327616018 0.2944378976156201 1.0 0.85998080187234 40 P17655,P48651,Q96N66,Q9NPH0,Q9Y2B2,Q9UBF8,Q01469,O15228,P42356,P35790,O95674 11 +Regulation of glial cell proliferation 0.7224867834393498 1.0473538422842903 0.2949364118488524 1.0 0.8604299454386558 4 Q96G23 1 +Mrna catabolic process 0.3858869984235771 1.0469671056119292 0.295114749763429 1.0 0.860444518197947 118 Q7Z739,Q969T7,Q92945,P16989,Q14103,Q9BQG2,Q9Y5A9,O60506,P98175,Q99729,P67809,P51114,Q14011,P31749,Q9NYY8,P51116,Q92804,Q6PGP7,P08670,P62312,Q9BRP8,P35637 22 +Positive regulation of neuron projection development 0.4188846742576533 1.0455625548228848 0.2957630451365456 1.0 0.8616802221250459 29 Q32P28,Q9UQB8,Q9Y639 3 +Cell motility involved in cerebral cortex radial glia guided migration 0.7775773970544034 1.0441269472050512 0.2964266599254932 1.0 0.8628394126204182 2 O94901 1 +Cellular response to corticosteroid stimulus 0.5090461699619659 1.0419952712994922 0.2974138713094518 1.0 0.8638458991234479 12 O95831,P06730 2 +Phospholipid biosynthetic process 0.3747758755156624 1.0410306545284531 0.2978613213627248 1.0 0.8643035839720888 57 P17655,Q96N66,Q01469,Q9NRA0,Q86YN1,Q9NPH0,Q9Y2B2,Q9UBF8,O75874,O15270,O15228,P42356,P35790,O95674 14 +Positive regulation of t cell proliferation 0.5306165856674641 1.0390534985924378 0.2987798559822194 1.0 0.8649595108559994 9 P04083,Q9HCL2,P04439,P02786 4 +Positive regulation of mitotic cell cycle 0.3797842803599198 1.0368478161168966 0.2998067870956928 1.0 0.8649595108559994 46 O00571,Q96DY7,P78536,Q9UJX3,Q9UJX4,Q9Y2S7,P31749,P11802,P04083,P06730,P31350,Q7LG56 12 +Cation transport 0.4046651441868024 1.035033317518051 0.3006533518395766 1.0 0.8649595108559994 154 P62942,P21796,P78417,O75844,Q9Y619,O75964,P12235,O43772,Q9HD20,Q9HC07,Q9UDW1,Q9NQ11,P31749,O15173,Q02790,P30536,P00846,Q70HW3 18 +Negative regulation of tor signaling 0.5453446014189236 1.0321023820549458 0.3020241580814895 1.0 0.8649595108559994 8 Q8IWV7 1 +Insulin receptor signaling pathway 0.4135796194917559 1.0299603906898047 0.3030285996565394 1.0 0.8649595108559994 31 P31749,P62993,P43490,Q9UQB8 4 +Response to phorbol 13 acetate 12 myristate 0.7736699729486026 1.0285371698126835 0.3036972156750093 1.0 0.8649595108559994 2 Q9NRA0 1 +Regulation of inflammatory response 0.405345328440997 1.0268373643898514 0.304497052038388 1.0 0.8649595108559994 35 P28070,Q9H000,P25786,P60900,O15360,P04083,Q8N2K0,P04062 8 +Steroid hormone biosynthetic process 0.6088042837043794 1.0268233117532668 0.304503670271357 1.0 0.8649595108559994 6 Q9UBM7,P30536 2 +Protein localization to extracellular region 0.3561129221371593 1.0267183483989135 0.304553106857572 1.0 0.8649595108559994 71 Q8N183,Q9H4A6,Q86YV9,P53985,Q16850,Q92614,Q32P28,Q96PC5,Q16836,P20645,Q9NQ11,P04083,Q8N5M9,P00367,O95563 15 +Peptidyl glutamic acid modification 0.6336776324547421 1.0263320739522983 0.3047350837585858 1.0 0.8649595108559994 5 P38435,Q8N0U8 2 +Lipoprotein biosynthetic process 0.4767588955635227 1.0260300219310146 0.3048774330924895 1.0 0.8649595108559994 14 Q16739,Q5MNZ6,Q9Y2B2,P04062 4 +Negative regulation of rna splicing 0.4422380175392157 1.0257571902393887 0.3050060495647715 1.0 0.8649595108559994 19 Q07021,P61978,P22626,P98175,Q13242,P38159,Q13247,P26368 8 +Sphingomyelin biosynthetic process 0.7162130208177293 1.02338057569302 0.306127939804329 1.0 0.8649595108559994 4 O15270 1 +Negative regulation of mrna processing 0.4329172615622111 1.0192620271015649 0.3080785863804975 1.0 0.8649595108559994 22 Q5VTR2,Q07021,P61978,P98175,Q13242,P22626,P38159,Q13247,P26368 9 +Cellular response to inorganic substance 0.3857980781904522 1.0159796695057886 0.3096390680112317 1.0 0.8649595108559994 43 O95831,P46108,Q9NQ11,P31749,P30536,P09601,Q14103,Q14168,P28482 9 +Regulation of immune effector process 0.3773490794431785 1.0158700207280438 0.3096912866413395 1.0 0.8649595108559994 47 P14174,O96028,Q9NRA0,Q92614,Q7KZ85,P02786,P46108,P04083,P09601,P04439,Q96FZ2,Q9NUQ9 12 +Negative regulation of notch signaling pathway 0.7990337897259205 1.0145489806425527 0.3103208699169992 1.0 0.8649595108559994 3 Q9Y5A9 1 +Apoptotic mitochondrial changes 0.4036677100188419 1.0131873915420933 0.3109706617488885 1.0 0.8649595108559994 35 P45880,O75832,P12235,P31749,Q9UII2,O14737,Q9H3K2,P52789,Q9Y3D6,P10909,Q96A26,O60313 12 +Peptidyl arginine methylation 0.6055282786160614 1.0129844994942143 0.311067564812503 1.0 0.8649595108559994 6 Q99873,Q86X55,Q6P2P2 3 +Peptidyl arginine n methylation 0.6055282786160614 1.0129844994942143 0.311067564812503 1.0 0.8649595108559994 6 Q99873,Q86X55,Q6P2P2 3 +Axon development 0.3562504689492192 1.0101139665474943 0.3124406915618867 1.0 0.8649595108559994 82 P35613,Q96G23,Q9UQB8,P11047,P00374,P42892,P30536,Q9UJX6,P41440,Q9Y639 10 +Intrinsic apoptotic signaling pathway in response to osmotic stress 0.7969723090655096 1.0070511997716134 0.3139101705720786 1.0 0.8673704961744393 3 P16989 1 +Positive regulation of release of cytochrome c from mitochondria 0.5718885878948701 1.0065318442928228 0.3141598012761486 1.0 0.8673704961744393 7 Q96A26 1 +Cellular response to insulin like growth factor stimulus 0.628364380800941 1.0045332664507125 0.3151216449313783 1.0 0.867945449405567 5 Q9BSK2 1 +Smooth muscle cell proliferation 0.4307705171301773 1.00446441486287 0.3151548151675896 1.0 0.867945449405567 22 Q5VZE5,P09493,P31749,P09601,O95140 5 +Inorganic ion transmembrane transport 0.3782188933982247 1.003783446316264 0.3154830050437214 1.0 0.8684809812437163 112 P62942,Q9UBX3,P12235,Q9HD20,Q8WWC4,P00846,Q06787,P42858,Q9UDW1,P21796,P78417,Q9HC07,Q7KZN9,P20674,O75964,Q02978,Q9UHG3,Q00535,P16615 19 +Pinocytosis 0.5390261085544096 1.0017802279397177 0.3164497486301507 1.0 0.8694311656405778 8 P50897,Q9Y5X3 2 +Positive regulation of calcium ion import 0.7667568379921859 1.0010477210965338 0.3168037378132027 1.0 0.8699042170650902 2 Q9NRA0 1 +Cellular response to insulin stimulus 0.3724871958562589 0.9970216829983906 0.3187539852755721 1.0 0.8719411880284604 54 P31749,Q9BSK2,P43490,Q9UQB8 4 +Atrial septum morphogenesis 0.7649534114818104 0.993897032919868 0.3202729990308284 1.0 0.8735207289820242 2 O96028 1 +Atrial septum development 0.7649534114818104 0.993897032919868 0.3202729990308284 1.0 0.8735207289820242 2 O96028 1 +Cardiac atrium morphogenesis 0.7649534114818104 0.993897032919868 0.3202729990308284 1.0 0.8735207289820242 2 O96028 1 +Neurotransmitter secretion 0.4347839053925536 0.9934161813963708 0.3205071791268032 1.0 0.8736958473127359 20 P50897,Q4J6C6,Q00535,Q9P253,P16615,O95721,Q06787 7 +Regulation of lymphocyte mediated immunity 0.4287870116747632 0.9907879656876798 0.3217891268227213 1.0 0.8742410168306661 22 O96028,Q7KZ85,P02786,P46108,P04439,Q96FZ2,Q9NUQ9 7 +Small molecule metabolic process 0.2970861510534227 0.9890412011050208 0.322642983837222 1.0 0.8742410168306661 499 P50897,Q969T7,P14174,Q9H773,P43490,Q8N4Q0,P37268,Q9UJ14,O75844,Q16836,Q15392,Q8WTV0,Q15067,Q06136,P48735,P00846,Q9BQG2,Q14739,Q9Y619,P00374,P17812,Q9NUJ1,Q15800,Q9UMR5,Q9H0P0,Q9BWD1,P41440,O60725,Q7LG56,P04062,P21796,Q16850,P78417,Q9H2D1,P48449,P23786,O75874,Q9HB40,P34896,P31749,Q13126,Q8NCC3,P35270,Q9BRR6,Q9NZ01,O95470,O95563,Q8N2K0,O15270,P07099,O60313,Q9NRW3,Q15125,O75964,P38435,Q9UBM7,Q9BTY2,Q8N0U8,Q14168,Q15120 60 +Epigenetic maintenance of chromatin in transcription competent conformation 0.5996416141695129 0.9881405382735186 0.3230838245719494 1.0 0.8742410168306661 6 O14757,Q969T9,O75151 3 +Positive regulation of cell adhesion molecule production 0.7911583230139094 0.9859472839224253 0.324158982162674 1.0 0.8755958870688998 3 P41440 1 +Regulation of lipophagy 0.7910960207469431 0.9857214834795304 0.3242698041885901 1.0 0.8755958870688998 3 O15270 1 +Negative regulation of signal transduction by p53 class mediator 0.5195294346729604 0.983640429089316 0.3252923393874756 1.0 0.8773069840023593 9 P14174,O75832,Q7LG56,Q8N2F6 4 +Negative regulation of small gtpase mediated signal transduction 0.4978874012744553 0.9821421794291144 0.3260298081996402 1.0 0.8781470496389169 12 Q9NUQ9 1 +Notch receptor processing 0.7616471295461349 0.9808105336246392 0.3266861827773666 1.0 0.8785439386201686 2 P78536 1 +Glutamate receptor signaling pathway 0.7616471295461267 0.9808105336246064 0.3266861827773828 1.0 0.8785439386201686 2 Q06787 1 +Positive regulation of g1 s transition of mitotic cell cycle 0.4425580592522526 0.979607918889821 0.3272796945159171 1.0 0.879389046250656 18 Q96DY7,P04083,P31749 3 +Regulation of protein polyubiquitination 0.5338449301402225 0.9769296520164508 0.3286039807492913 1.0 0.8809659955769406 8 O00571,Q96FW1,O95071 3 +Serine family amino acid biosynthetic process 0.5181472628773793 0.976734859946644 0.3287004322887168 1.0 0.8809659955769406 9 P00374,P34896 2 +Amyloid beta metabolic process 0.4489943778877815 0.9759745707041396 0.3290770660742865 1.0 0.8816115788310301 17 Q16799,O95197,P15260,P10909,Q92542,P42574 6 +Regulation of leukocyte mediated immunity 0.4027271582274541 0.9731133139193564 0.330496987656093 1.0 0.8839569348594185 33 O96028,Q9NRA0,Q7KZ85,P02786,P46108,P09601,P04439,Q96FZ2,Q9NUQ9 9 +Regulation of fatty acid transport 0.6201245663834789 0.9707984865487614 0.3316486364090432 1.0 0.8851808271350855 5 P31749 1 +Amyloid beta formation 0.4611859924808631 0.9705499779684584 0.3317724258156449 1.0 0.8851808271350855 15 Q16799,O95197,P15260,P10909,Q92542,P42574 6 +Regulation of nitric oxide metabolic process 0.4952544263160825 0.968020957832476 0.3330339029987033 1.0 0.8859984293623838 12 P31749,Q92945,P30536,P06280 4 +Chemical homeostasis 0.4111820501634992 0.9672100282600936 0.3334390500068396 1.0 0.8867130183228569 186 P62942,P50897,Q16739,Q9P035,P30519,Q9HD20,Q8WTV0,Q15067,Q9NQ11,P42785,Q5BJF2,O15118,Q9Y487,Q8WWC4,Q86YV9,P53985,Q93050,P42858,Q9Y5X3,P09601,O75503,O75880,P04062,Q8N511,P78417,P62995,P31749,P30536,P52789,Q9HC07,O95563,Q9Y639,P02786,P16615,Q00535,Q8N5M9,Q01469,P28482,Q15120,Q9Y6C9 40 +Visual behavior 0.6184962899732322 0.9641435492357971 0.3349739616171829 1.0 0.8872373587423441 5 Q9Y639 1 +Regulation of receptor signaling pathway via stat 0.53116798062811 0.964096836475062 0.3349973786147566 1.0 0.8872373587423441 8 P30153,Q9NX40,Q00535 3 +Membrane raft organization 0.5153599211353437 0.9628116646717114 0.3356420458591067 1.0 0.8878449881095882 9 P50897,P41440 2 +Vacuolar proton transporting v type atpase complex assembly 0.7568379921851343 0.9618311221289098 0.3361344419453129 1.0 0.887871141561083 2 Q8N511 1 +Proton transporting v type atpase complex assembly 0.7568379921851343 0.9618311221289098 0.3361344419453129 1.0 0.887871141561083 2 Q8N511 1 +Negative regulation of viral transcription 0.6178830512218323 0.9616382290760324 0.3362313611567082 1.0 0.887871141561083 5 P19474 1 +Response to hydrogen peroxide 0.4077769438116572 0.9612515001042444 0.3364257274812678 1.0 0.887871141561083 29 Q99720,O95831,P46108,P30048,P04083,P09601,P42574 7 +Regulation of neurotransmitter levels 0.4102113207894291 0.9600444517072576 0.3370328433698573 1.0 0.8882675669009144 27 P50897,P21964,Q4J6C6,Q00535,Q9P253,P41440,P16615,O95721,Q06787 9 +Positive regulation of protein dephosphorylation 0.4593123133661431 0.9593504953807842 0.3373822051671804 1.0 0.8884671696495011 15 Q86XL3 1 +Cell maturation 0.4267295739357353 0.9571892423414984 0.3384717458602662 1.0 0.8888013358088719 21 Q9Y5A9,P30153,O75503 3 +Axonal transport of mitochondrion 0.616729511446127 0.9569271631090052 0.3386040198323297 1.0 0.8888013358088719 5 P07196,O60313 2 +Labyrinthine layer morphogenesis 0.7818469514699051 0.9522873775908188 0.3409512575279649 1.0 0.8919691200374128 3 Q15363 1 +Phosphatidylglycerol metabolic process 0.5046773233190343 0.94904524239679 0.342597602252471 1.0 0.894138589769663 11 Q8NCC3 1 +Anaphase promoting complex dependent catabolic process 0.527891986280932 0.948399924446073 0.3429258978838621 1.0 0.8943617593806427 8 Q16763,Q9UJX4,Q9UJX3 3 +Negative regulation of sprouting angiogenesis 0.7532311391644149 0.94764173898694 0.3433118699197686 1.0 0.8948075622865549 2 P57105 1 +Inflammatory cell apoptotic process 0.6144252283665063 0.9475228618587156 0.3433724122602548 1.0 0.8948075622865549 5 P04083,O75844 2 +Chloride transmembrane transport 0.7799158147925287 0.9453294174419608 0.3444907243757766 1.0 0.8960141630038978 3 Q9UHG3,P51790 2 +Cellular transition metal ion homeostasis 0.429883851269127 0.9442591399463144 0.3450372404735242 1.0 0.8963699849019373 19 Q9NQ11,O75880,P09601,Q9Y487 4 +Negative regulation of protein targeting to mitochondrion 0.7790138304269271 0.9420823659718436 0.3461504719695307 1.0 0.8970795412770195 3 P49257,O95429 2 +Protein dephosphorylation 0.3500469462730848 0.9412668977653778 0.3465681018232533 1.0 0.8970795412770195 70 P62942,P42858,P30154,Q86XL3,P30153,P04062 6 +Multicellular organismal movement 0.5108360987795977 0.9402246174351404 0.3471023569920393 1.0 0.8975588117325994 9 P78417 1 +Humoral immune response mediated by circulating immunoglobulin 0.7784125075165209 0.9399186805895516 0.3472592744604079 1.0 0.8975588117325994 3 P10909,Q9UQ84 2 +Positive regulation of dephosphorylation 0.4493618026155564 0.9372209382138892 0.3486449215368716 1.0 0.8997698020817385 16 Q86XL3 1 +Meiotic cell cycle process 0.3816614462427173 0.9362191603949408 0.3491603600067887 1.0 0.9004953843860548 41 O94901,P46379,Q92791,Q08J23,O43683,O15360,P30153,O60566,Q9BTX1,Q9Y5A9,Q15645,Q9Y2W6 12 +Regulation of phospholipase a2 activity 0.6114649227356069 0.9354542638334034 0.3495542430731899 1.0 0.900978160443832 5 P50897,P04083 2 +Positive regulation of extrinsic apoptotic signaling pathway in absence of ligand 0.6927128782167495 0.9341436312209892 0.3502298080287778 1.0 0.9013006959733024 4 P30154 1 +Embryonic placenta morphogenesis 0.6925785278973031 0.9336364336949916 0.350491464868961 1.0 0.9013360276699612 4 Q15363 1 +Oligosaccharide lipid intermediate biosynthetic process 0.7766085387853168 0.9334325617648084 0.3505966747604438 1.0 0.9013360276699612 3 Q86YN1,O75340 2 +Sulfate transport 0.7762249870828144 0.9320544773570456 0.3513083723617622 1.0 0.9028082984239352 3 Q02978 1 +Hematopoietic stem cell proliferation 0.585882694223971 0.9302191998094612 0.3522576029257231 1.0 0.9041742582607296 6 Q9Y5A9 1 +Positive regulation of ryanodine sensitive calcium release channel activity 0.7749174872047782 0.9273592646814208 0.3537400332079965 1.0 0.905437600891974 3 P78417 1 +Regulation of nervous system process 0.4873547855948089 0.9256709373431884 0.3546170157550603 1.0 0.9062900040587808 12 Q01469,Q9UQB8,P04062 3 +Regulation of mitochondrial membrane permeability 0.4532760925920198 0.9232765507333214 0.3558631047548246 1.0 0.9076064820791032 15 P12235,P45880 2 +Intrinsic apoptotic signaling pathway 0.3486235146379282 0.921980751762174 0.3565386158436003 1.0 0.9084498869893306 82 P14174,P45880,P46379,Q9NR28,P61978,O95831,P31749,P16989,P09601,O95881,Q96K76,Q7LG56,O60313 13 +Peptidyl cysteine modification 0.5222095131487439 0.921196316164266 0.3569479412302625 1.0 0.9084498869893306 8 Q8N4Q1,P30048 2 +Response to peptide hormone 0.3549416020398078 0.9203235697195664 0.3574036957262603 1.0 0.9084498869893306 90 O60343,Q9BSK2,P62993,P43490,Q9UQB8,P46108,Q16836,Q99523,P31749,Q9Y5X3,P04083,P07196,P35613 13 +Negative regulation of protein serine threonine kinase activity 0.4185289033469209 0.9200187192062887 0.3575629771686288 1.0 0.9084498869893306 22 O95373,P53350,Q96SZ6,O94992,P31749,P42771,P42574,P04062 8 +Regulation of tumor necrosis factor mediated signaling pathway 0.552431990648049 0.9192206433359204 0.3579801756707264 1.0 0.9084498869893306 7 Q13546,P78536,Q8TCT8 3 +Cerebellar purkinje cell layer morphogenesis 0.772399278412494 0.9183278225086648 0.3584472654640041 1.0 0.9090976715659916 3 Q15058,P04062 2 +Negative regulation of response to biotic stimulus 0.4123000403388647 0.918197609593323 0.3585154199076847 1.0 0.9090976715659916 24 Q7Z739,P19474,Q9Y3Z3,P46108,O43657,Q9Y4E8,P04439,P01889,Q9Y5A9 9 +Actin cytoskeleton reorganization 0.4088724466344056 0.9168251213699832 0.3592342864141655 1.0 0.9105649711060076 25 Q13576,P62993,Q9UQB8,P11233,P04083,Q9Y5S2 6 +Cellular response to muramyl dipeptide 0.7699249823689034 0.909468848758315 0.3631026939401134 1.0 0.9134010894757632 3 P08670 1 +Myeloid cell apoptotic process 0.5499045200189028 0.9079108974263304 0.3639252996322386 1.0 0.9134010894757632 7 P14174,P04083,P78536 3 +Regulation of insulin secretion 0.4138091043880943 0.9072735370614784 0.3642621645611141 1.0 0.9134010894757632 23 Q8N183,P53985,Q16836,Q8N5M9,O95563 5 +Disaccharide metabolic process 0.7427111511872537 0.906493680930128 0.3646746080329488 1.0 0.9134010894757632 2 P15291 1 +Negative regulation of protein k63 linked ubiquitination 0.6848978930318903 0.9047056533937512 0.3656213452843846 1.0 0.9134010894757632 4 O95071,Q96FW1 2 +Negative regulation of protein polyubiquitination 0.6848978930318903 0.9047056533937512 0.3656213452843846 1.0 0.9134010894757632 4 O95071,Q96FW1 2 +Sphingolipid mediated signaling pathway 0.6848829520582114 0.9046495040749724 0.365651100440612 1.0 0.9134010894757632 4 P31749 1 +Response to hyperoxia 0.6848478097310224 0.9045174385739392 0.3657210917468954 1.0 0.9134010894757632 4 P00846 1 +Positive regulation of cold induced thermogenesis 0.4559184721373687 0.904295643437873 0.3658386562559994 1.0 0.9134010894757632 14 Q16836,P23786,O95140 3 +Cytoplasmic pattern recognition receptor signaling pathway 0.4305957472662155 0.902700483938709 0.3666848795469128 1.0 0.9136871233344042 18 Q9NUD5 1 +Signal peptide processing 0.6843579301227211 0.9026767617275508 0.3666974732516037 1.0 0.9136871233344042 4 O75503 1 +Pigment metabolic process 0.399625321028456 0.8992697608309084 0.3685089901313141 1.0 0.9165443821956162 29 P30519,P34896,P34897,P30536,P09601 5 +Positive regulation of mrna metabolic process 0.3431184249749047 0.898378386598344 0.368983855170979 1.0 0.9173741024044172 72 Q7Z739,Q969T7,Q92945,Q14011,P62995,P38159,P98179,Q9Y5A9,P67809,O60506 10 +Activation of cysteine type endopeptidase activity 0.7663315680150116 0.896630270646211 0.369916239873842 1.0 0.91832754572066 3 Q9BXI6 1 +Apoptotic process involved in development 0.5472010518203293 0.8958240325566617 0.3703467522981967 1.0 0.91832754572066 7 P30154 1 +Negative regulation of dna damage response signal transduction by p53 class mediator 0.6017111256376795 0.8958044205012652 0.3703572285559606 1.0 0.91832754572066 5 P14174,O75832 2 +Regulation of rna splicing 0.354042678803284 0.8917482356042472 0.3725278929617179 1.0 0.9200815786316684 92 Q13242,P55795,O60828,Q06787,Q15007,P61978,Q9BWF3,P98175,Q92841,Q8NDT2,Q8IY67,P31942,Q9UHX1,Q13247,P51114,P31943,Q5BKZ1,O75525,Q07955,P22626,Q14011,P62995,P52597,Q07666,P09651,P26368,P08621,P51116,Q96QD8,P38159,P98179,P35637 32 +Protein modification by small protein removal 0.3668710033307349 0.8913282406002111 0.3727531024992834 1.0 0.9200815786316684 45 P19474,Q96FW1,Q9H8M7,O95630,P34897,Q9Y4E8,Q96K76,Q04323,Q9BWJ5 9 +Protein localization to microtubule end 0.7388037270814363 0.8913064237680492 0.372764803415448 1.0 0.9200815786316684 2 Q15555 1 +Maintenance of protein location 0.3922304385834938 0.8895237664239989 0.3737216561709227 1.0 0.9212879477935436 33 Q9H4A6,O94901,O75832,P31749,O43731,P30536,Q00535,P52789,P36404,P24390 10 +Adp transport 0.6808036142794932 0.8893387983456199 0.3738210259371708 1.0 0.9212879477935436 4 P12235,P05141 2 +Sex differentiation 0.3715748973361769 0.8882562938277445 0.3744029038951566 1.0 0.9217069867684056 43 Q02790,Q15392,O75874 3 +Sterol transport 0.399423153454402 0.8882392495263594 0.3744120701841429 1.0 0.9217069867684056 28 Q86Y82,Q9UHB6,Q9P260,Q9H4L5,Q8WTV0,O15118,P30536,P10909 8 +Regulation of dna damage response signal transduction by p53 class mediator 0.4928087659365665 0.8879509366037545 0.3745671435955171 1.0 0.9217069867684056 11 P14174,O75832,O75844 3 +Programmed necrotic cell death 0.4471799937508208 0.8868657214957473 0.3751511987192026 1.0 0.9220603303259292 15 P49327,P12235,P16989,Q13510 4 +Prolactin secretion 0.7376014427411898 0.8866445155136339 0.3752703192256592 1.0 0.9220603303259292 2 P04083 1 +Tetrahydrofolate metabolic process 0.4922950327909356 0.8853095256653165 0.3759897137770647 1.0 0.922259222873136 11 P00374,P34896 2 +Regulation of cardiac muscle cell action potential involved in regulation of contraction 0.7629099177518031 0.8844364698683075 0.3764606430868034 1.0 0.922259222873136 3 P16615 1 +Phosphatidylinositol acyl chain remodeling 0.737000300571087 0.8843155586897263 0.3765258916740539 1.0 0.922259222873136 2 Q96N66 1 +Positive regulation of fatty acid biosynthetic process 0.7370003005710665 0.8843155586896461 0.3765258916740972 1.0 0.922259222873136 2 P04083 1 +Phospholipid catabolic process 0.4524105302469753 0.8838251903713901 0.376790585877502 1.0 0.922259222873136 14 Q8NCC3,O75874,Q8WTV0 3 +Negative regulation of peptide secretion 0.5439717946187969 0.8814016502775486 0.3781004647750834 1.0 0.922259222873136 7 Q16836,Q8N5M9 2 +Negative regulation of hormone secretion 0.5439717946187969 0.8814016502775486 0.3781004647750834 1.0 0.922259222873136 7 Q16836,Q8N5M9 2 +Negative regulation of innate immune response 0.4401567733657949 0.8809197874400979 0.3783612366657118 1.0 0.922259222873136 16 Q7Z739,P19474,P46108,Q9Y4E8,P04439,P01889,Q9Y5A9 7 +Positive regulation of blood vessel endothelial cell migration 0.4656210216078037 0.8798012239326213 0.3789670015215556 1.0 0.922259222873136 13 P31749,P04083,P09601 3 +Cellular response to reactive oxygen species 0.3908449771271682 0.8784810460492042 0.3796827192318908 1.0 0.922259222873136 33 Q99720,O95831,P00374,P09493,P31749,P30048,P04083,P28482,O15111 9 +Vesicle docking 0.4330933092783789 0.8762994186341275 0.3808672810243141 1.0 0.922259222873136 17 O43752,Q7Z6M1 2 +Regulation of t cell mediated immunity 0.5727527448711592 0.8751999093092413 0.3814651425648794 1.0 0.922259222873136 6 P01889,Q9NUQ9,P04439 3 +Regulation of leukocyte migration 0.3976803602722253 0.8751276413029432 0.3815044586744869 1.0 0.922259222873136 28 P14174,P46108,P31749,P04083,P09601,P28482 6 +Postsynaptic cytoskeleton organization 0.6768867388457371 0.8746762140890578 0.3817501058115784 1.0 0.922259222873136 4 P07196 1 +Tissue migration 0.3593701139716149 0.8735968168403434 0.3823378603289999 1.0 0.922259222873136 55 Q15555,Q8WTV0,P42785,P31749,P04083,P09601,O75340 7 +Regeneration 0.388402844498981 0.8732203357041164 0.382542992666246 1.0 0.922259222873136 34 Q96G23,P11047,P00374,P07196,P09601,P30536 6 +Response to wounding 0.3500649306957495 0.8729235011683583 0.3827047757136286 1.0 0.922259222873136 89 Q86YV9,Q96G23,P11047,P46108,P00374,P38435,P09493,Q8WTV0,P42785,P30536,P09601,Q96AY3,P49257 13 +Insulin secretion 0.3971485799728484 0.8711268556535479 0.3836848920366438 1.0 0.922259222873136 28 Q8N183,P53985,Q16836,P04083,Q8N5M9,O95563 6 +Positive regulation of cell migration involved in sprouting angiogenesis 0.7588903975837296 0.8701523390880039 0.3842171581095448 1.0 0.922259222873136 3 P09601 1 +Response to mitochondrial depolarisation 0.5410342091021356 0.8682974305357984 0.3852315284431036 1.0 0.922259222873136 7 O95140,P04062 2 +Binding of sperm to zona pellucida 0.4765922437475323 0.8680521287309279 0.3853657959636569 1.0 0.922259222873136 12 P48643,P45880,Q14157,P15291 4 +Sperm egg recognition 0.4765922437475323 0.8680521287309279 0.3853657959636569 1.0 0.922259222873136 12 P48643,P45880,Q14157,P15291 4 +Cytokine production involved in immune response 0.4889058227321569 0.8678917461343593 0.3854535978683857 1.0 0.922259222873136 11 P14174,Q9NRA0,P09601 3 +Positive regulation of neuron apoptotic process 0.4764232993933448 0.867148710826679 0.385860534115539 1.0 0.922259222873136 12 O95831,Q00535 2 +Serine transport 0.6745564789340878 0.8659716595574639 0.3865057035821642 1.0 0.9229037357982226 4 Q96QD8 1 +Xenobiotic transport 0.6744781394177997 0.8656792746696066 0.3866660686387737 1.0 0.9229037357982226 4 P41440 1 +Response to corticosterone 0.7575392407786765 0.8653608330043042 0.3868407713031663 1.0 0.9229037357982226 3 P07196 1 +Response to ether 0.6742450789785776 0.8648095246384019 0.3871433425453836 1.0 0.9232863997391558 4 Q9H4A6,Q14103 2 +Negative regulation of gliogenesis 0.5938300983072685 0.8639126496037097 0.3876358773522939 1.0 0.9235727557887844 5 Q96G23 1 +Regulation of filopodium assembly 0.4754514258929435 0.8619524460532275 0.3887136867389413 1.0 0.92467568521881 12 P51116,P11233,P51114 3 +Progesterone receptor signaling pathway 0.5931909275367155 0.8613324443968213 0.3890549714098879 1.0 0.92467568521881 5 Q969T9 1 +Regulation of extrinsic apoptotic signaling pathway 0.3917776548759075 0.8604703904920659 0.3895297985476453 1.0 0.9248686792449994 31 P30154,P31749,P30153,P09601 4 +Cellular response to lipoprotein particle stimulus 0.5690817459183177 0.8598725862506622 0.3898592814601136 1.0 0.9250077361351764 6 O15118,P31749 2 +Regulation of defense response 0.3542413610610879 0.8583753497118244 0.3906852345724843 1.0 0.9255950037871918 96 Q7Z739,P28070,P25786,O75844,O15360,Q9Y4E8,Q9Y5A9,O60828,P60900,Q96PK6,P04062,P19474,Q9H000,Q13546,O94992,Q9NUD5,Q9NZ08,Q8N2K0,P46108,O43657,P04083,P04439 22 +Monoubiquitinated protein deubiquitination 0.5686645082891899 0.8581322362549116 0.3908194487811025 1.0 0.9255950037871918 6 Q9BWJ5,Q96K76 2 +Cell death in response to oxidative stress 0.4006567543009748 0.8573492505117181 0.3912518974077821 1.0 0.92560649244668 25 Q99720,Q9NR28,P04062 3 +Filopodium assembly 0.4612990147893474 0.8556946356681412 0.3921667081779107 1.0 0.9267578613199972 13 P51116,P11233,P51114 3 +Placenta blood vessel development 0.5374791643195166 0.8524601690609832 0.3939587371059392 1.0 0.9287819140922916 7 P31749,Q15363 2 +Positive regulation of mrna processing 0.4134804907180111 0.8508192728761572 0.3948697539029653 1.0 0.9294328835305 20 Q14011,P98179,P38159 3 +Positive regulation of t cell mediated immunity 0.5904860867388639 0.8504246447856058 0.3950890391906609 1.0 0.9294328835305 5 P01889,Q9NUQ9,P04439 3 +Histone lysine demethylation 0.5072263743568832 0.8496678292390516 0.3955097892180719 1.0 0.929920554374424 8 Q9H6W3,Q8NB78 2 +Response to misfolded protein 0.4888741707391451 0.8486456880587103 0.3960784760715732 1.0 0.9305838001479004 10 Q9BUN8,P46379 2 +Nuclear transcribed mrna catabolic process deadenylation dependent decay 0.3869762946732997 0.8476401707124434 0.396638395492205 1.0 0.9315622930655983 33 Q969T7,P67809,O60506 3 +Cerebellar cortex morphogenesis 0.5650278550410524 0.8429789142493109 0.3992402366101297 1.0 0.935305229634265 6 Q15058,Q00535,P04062 3 +Regulation of peptidase activity 0.3432409291108844 0.8404562408081274 0.4006526269682184 1.0 0.9359627090026552 84 Q9BXK5,Q9NR28,Q15041,P04080,O95831,Q15392,Q9NQ11,P31749,P07858,P30086,O14737,Q9BXI6,Q96K76,P49327,O75340,Q96A26 16 +Positive regulation of viral life cycle 0.5347325064666406 0.8402413720621624 0.4007730659135011 1.0 0.9359627090026552 7 P19474 1 +Retrograde axonal transport 0.4907573017126943 0.8402281632116546 0.4007804704919109 1.0 0.9359627090026552 9 Q14168 1 +Lipid storage 0.4204132286068798 0.8372989558515083 0.4024245460374391 1.0 0.9373547352823278 18 P04062,P17900,Q8WTV0,O95674 4 +Er associated misfolded protein catabolic process 0.5336006340957491 0.835210729158405 0.4035990697865639 1.0 0.9390159272448684 7 P46379 1 +Alpha beta t cell proliferation 0.7234746017433143 0.8322852883457141 0.4052479325930622 1.0 0.9397302428838654 2 P04439 1 +Lymphocyte anergy 0.7234746017433143 0.8322852883457141 0.4052479325930622 1.0 0.9397302428838654 2 P01889 1 +T cell tolerance induction 0.7234746017433143 0.8322852883457141 0.4052479325930622 1.0 0.9397302428838654 2 P01889 1 +Negative regulation of cellular macromolecule biosynthetic process 0.3667261691156722 0.8310436435900375 0.4059489746852347 1.0 0.9397302428838654 117 Q7Z739,Q969T7,Q96PZ0,Q92945,Q9BXS4,P34897,Q14103,Q9Y5A9,Q06787,O60506,P00374,P67809,P51114,Q99543,Q14011,P34896,O14757,P09651,P51116,P06730 20 +Homophilic cell adhesion via plasma membrane adhesion molecules 0.4888424683321288 0.8307229645720403 0.40613015011597 1.0 0.9397302428838654 9 Q9Y639 1 +Small gtpase mediated signal transduction 0.3555905809875192 0.8306697624067666 0.4061602126451742 1.0 0.9397302428838654 101 P62993,Q15555,P46108,Q02818,Q15392,P11233,P80303,P53365,Q9Y2I1,P09601,P41440,O95140,Q9NUQ9 13 +Negative regulation of regulated secretory pathway 0.6650488512456794 0.830610255708103 0.4061938392015722 1.0 0.9397302428838654 4 P09601 1 +Negative regulation of protein containing complex assembly 0.3694728282530912 0.8292145323454108 0.4069830231466362 1.0 0.940169812866946 41 Q02790,P45880,Q9NUQ9,P04062 4 +Aminoglycan biosynthetic process 0.4884940478876296 0.828994151006581 0.4071077169359181 1.0 0.940169812866946 9 Q8NCH0,O43505 2 +Regulation of hormone secretion 0.389079148403652 0.8287095447342613 0.4072687834930548 1.0 0.940207422681798 30 Q8N183,P53985,Q16836,P04083,Q8N5M9,O95563 6 +Regulation of endoplasmic reticulum tubular network organization 0.5844802863934839 0.8262725283951206 0.4086495134874823 1.0 0.941053170421174 5 Q15041 1 +Regulation of unsaturated fatty acid biosynthetic process 0.663787061210451 0.8259368980252711 0.4088398882591737 1.0 0.9411578285555032 4 P04083 1 +Neuron projection guidance 0.3992343276054463 0.825168914357773 0.4092756991034076 1.0 0.9412420287251548 24 P35613,P11047,O00264,P42892,Q00535,Q7L576,Q9Y639 7 +Glycolipid transport 0.7453397474443607 0.822342877877494 0.4108817797742643 1.0 0.9412420287251548 3 P61916,P07602 2 +Regulation of dna methylation 0.5009810592846174 0.8199671242031599 0.4122348490190719 1.0 0.9412420287251548 8 Q8NB78,O75844 2 +Vascular process in circulatory system 0.387797475212577 0.8188492525462744 0.4128724263612411 1.0 0.9412420287251548 30 P08183,P53985,Q96QD8,Q9HB40,P42892,P41440,Q01469 7 +Response to epidermal growth factor 0.4237766515550988 0.8179979917862857 0.4133583339806597 1.0 0.9412420287251548 17 O95429,P31749,Q9UQB8 3 +Cell cell recognition 0.4545187858583622 0.8179342435531793 0.4133947356935203 1.0 0.9412420287251548 13 P48643,P45880,Q14157,P15291 4 +Circadian regulation of gene expression 0.4097037369725502 0.8112112625549098 0.4172443589412764 1.0 0.9412420287251548 19 Q9BQG2,P43490 2 +Leukocyte mediated cytotoxicity 0.4286540229317749 0.8106938456479806 0.4175415084970817 1.0 0.9412420287251548 16 O15400,P46108,P04439,P01889,Q9NUQ9 5 +Histone h2a k63 linked ubiquitination 0.7418935050377969 0.8102750358689803 0.4177821198430163 1.0 0.9412420287251548 3 Q96FW1 1 +Nucleobase transport 0.7411304870715434 0.8076084445977396 0.4193160238970681 1.0 0.9412420287251548 3 P12235,Q9Y277 2 +Regulation of high voltage gated calcium channel activity 0.7168620378719528 0.807125706793346 0.419594062928516 1.0 0.9412420287251548 2 P0DP25 1 +Regulation of cell communication by electrical coupling involved in cardiac conduction 0.7168620378719528 0.807125706793346 0.419594062928516 1.0 0.9412420287251548 2 P0DP25 1 +Receptor localization to synapse 0.4651154777723379 0.8067838746307618 0.4197910110777934 1.0 0.9412420287251548 12 Q9Y639 1 +Synaptic transmission dopaminergic 0.6585168281623868 0.8064700686808641 0.4199718596224517 1.0 0.9412420287251548 4 P41440 1 +Regulation of natural killer cell mediated immunity 0.5553365533819667 0.8027457506414978 0.4221217035718203 1.0 0.9412420287251548 6 P46108,P04439 2 +Nadh dehydrogenase complex assembly 0.3841921419163764 0.8014273714500204 0.422884274535817 1.0 0.9412420287251548 31 Q8N183,Q9H061,O43676,Q15070,Q9Y6M9,Q96CU9,O75306,O75438,O95168,Q86Y39 10 +Regulation of anion channel activity 0.7393129640723397 0.8012644637285752 0.4229785588580381 1.0 0.9412420287251548 3 P08183 1 +Dendrite extension 0.5779989073098173 0.8003205845948482 0.4235250796881118 1.0 0.9412420287251548 5 Q7L576,Q96F07 2 +Positive regulation of smooth muscle cell proliferation 0.4753772874369734 0.7985452254518607 0.4245541593304704 1.0 0.9412420287251548 11 P31749,P09601 2 +Mitochondrial adp transmembrane transport 0.7384014775101817 0.79808719259806 0.4248198931619078 1.0 0.9412420287251548 3 P12235 1 +Cellular response to zinc ion 0.7373650381119103 0.7944778347095662 0.4269173077007768 1.0 0.9439567573063824 3 P30536 1 +Protein deglycosylation 0.553017094447328 0.7931517570555842 0.4276894110296714 1.0 0.9446163618483052 6 O60502 1 +Response to nitric oxide 0.4952697540234196 0.7928806018575417 0.4278473901159971 1.0 0.9446163618483052 8 P46108,O95831 2 +Regulation of response to oxidative stress 0.3974564208924483 0.7927451896338211 0.4279262960266474 1.0 0.9446163618483052 23 P00374,Q9UJ14 2 +Learning 0.3999519806545581 0.7919392570110916 0.4283960953736314 1.0 0.9449742674444166 22 P50897,P18085,P42858,Q00535,Q9Y639 5 +Cellular response to peptide hormone stimulus 0.3403181643520399 0.7886750850381121 0.4303019335357245 1.0 0.9466068356705598 67 O60343,Q9BSK2,P43490,Q9UQB8,P31749 5 +Regulation of synaptic vesicle recycling 0.551797593060454 0.7881133902685963 0.4306303834942322 1.0 0.9466068356705598 6 Q7L576,P0DP25,Q00535 3 +Lymphocyte mediated immunity 0.3741653661824592 0.7876293066918412 0.4309135671319781 1.0 0.9466068356705598 36 O96028,Q9UQ84,Q7KZ85,P02786,P46108,P04439,P01889,Q96FZ2,Q9NUQ9 9 +Regulation of cardiac muscle contraction by calcium ion signaling 0.5512159056213872 0.7857116062952476 0.4320364621001609 1.0 0.9466068356705598 6 P16615,P78417 2 +Leukocyte differentiation 0.3461201504216887 0.7836284421365708 0.4332581617225794 1.0 0.9466068356705598 61 O96005,O00625,P78536,O15360,P04083,Q8N5M9,P49327,Q14739,P24390,P04062 10 +Aggrephagy 0.5737914262370434 0.7835414128724603 0.4333092446535289 1.0 0.9466068356705598 5 P42858,Q5T8D3 2 +Golgi organization 0.3476803174777342 0.7829501778235664 0.4336563697786109 1.0 0.9466068356705598 59 Q96JB2,O15027,Q9BVK6,Q92614,Q9P2W9,P42858,Q15363,P49257,P28482,O43752,Q7RTS9 11 +Intrinsic apoptotic signaling pathway in response to dna damage 0.3871070732027001 0.7817120883016694 0.4343837958574481 1.0 0.9466068356705598 26 P14174,P46379,P09601,P61978 4 +Regulation of reactive oxygen species metabolic process 0.3789898601285574 0.7718916228456086 0.4401786193187387 1.0 0.9494027946671628 32 Q9BSK2,P00374,P42785,P30536,Q15120 5 +Positive regulation of metaphase anaphase transition of cell cycle 0.5472591245698967 0.7693998256976213 0.4416559920407685 1.0 0.9494027946671628 6 Q9UJX3 1 +Regulation of peptide transport 0.3884554047756899 0.7691163547422025 0.4418242400790988 1.0 0.9494027946671628 25 Q8N183,P53985,Q16836,Q8N5M9,O95563 5 +Positive regulation of amyloid precursor protein biosynthetic process 0.7063420498947999 0.7675136216212723 0.4427761974872628 1.0 0.9494027946671628 2 Q92542 1 +Axon ensheathment in central nervous system 0.7287341820220131 0.7645697382754272 0.4445277948427153 1.0 0.9507743700045088 3 P10909 1 +Negative regulation of glial cell proliferation 0.7280205970704008 0.7621092424694793 0.4459948070642188 1.0 0.9512708211121402 3 Q96G23 1 +Multicellular organism growth 0.3832654998048537 0.759632864755292 0.4474740686769975 1.0 0.9522779385525114 27 Q15363,O95470 2 +Oligosaccharide metabolic process 0.5447775645040064 0.7591933979921417 0.4477368747990793 1.0 0.9522779385525114 6 P06280,P17900,Q13724,P15291 4 +Vesicle targeting 0.3949167533202247 0.7573102810241344 0.4488639929025619 1.0 0.9522779385525114 22 O15027,Q9BVK6,Q15363,Q92734,O95721 5 +Negative regulation of inflammatory response 0.4305275177611143 0.7565585793025635 0.449314364660264 1.0 0.9526109970955776 14 P28070,P04062 2 +Positive regulation of cell morphogenesis involved in differentiation 0.389388490384896 0.7551918630903275 0.4501338701976629 1.0 0.9537257269375604 24 P46108,Q9UQB8 2 +Calcium ion export 0.6439639686209928 0.7531953628198854 0.4513325255104545 1.0 0.9546167475463564 4 P0DP25,O95202 2 +Negative regulation of amyloid fibril formation 0.4861038651345066 0.7495864915880454 0.4535037890917688 1.0 0.9546167475463564 8 P10909,Q9UHV9,O60925 3 +Regulation of amyloid fibril formation 0.4861038651345066 0.7495864915880454 0.4535037890917688 1.0 0.9546167475463564 8 P10909,Q9UHV9,O60925 3 +Phosphatidylglycerol biosynthetic process 0.7242934455802611 0.7492893938306077 0.4536827990192378 1.0 0.9546167475463564 3 Q9HCL2,O95674 2 +Embryonic placenta development 0.4239186986971855 0.7484265329122359 0.4542029234258977 1.0 0.9546167475463564 15 P31749,Q15363,P28482 3 +Glycosyl compound catabolic process 0.4648116118303015 0.7446565105754872 0.4564793961396376 1.0 0.9560748167135976 11 Q9NRW3,Q13126,Q9NUJ1,P04062 4 +Positive regulation of rna splicing 0.3905497208105856 0.7444941716235809 0.4565775659632285 1.0 0.9560748167135976 23 P98179,Q14011,P62995,P38159 4 +Positive regulation of immune effector process 0.363426242946276 0.7426485623408222 0.4576944792119426 1.0 0.9560748167135976 39 P14174,O96028,Q9NRA0,Q92614,P02786,P04083,P09601,P04439,Q96FZ2,Q9NUQ9 10 +Negative regulation of extrinsic apoptotic signaling pathway 0.3927116656873058 0.7421648522077742 0.457987461047415 1.0 0.9560748167135976 22 P31749,P09601 2 +Ameboidal type cell migration 0.3288347610913626 0.740959194920057 0.4587181820101094 1.0 0.956606462482372 77 Q15555,Q8WTV0,O95429,P42785,P31749,P04083,P09601,O95470 8 +Negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator 0.5403291123199344 0.7409458482850573 0.4587262747521923 1.0 0.956606462482372 6 P14174,Q7LG56,Q8N2F6 3 +Fibroblast migration 0.4171503975387973 0.7407272838476097 0.4588588128476423 1.0 0.956606462482372 16 O95429,P31749,O95470 3 +Ruffle organization 0.4050811770982674 0.7391531577811706 0.4598140010143319 1.0 0.956915294750558 18 Q9UHB6,P09493,O95429,P53365,Q7L576 5 +Glycosyl compound metabolic process 0.378500437260114 0.7386624832807056 0.4601119723328515 1.0 0.956915294750558 29 Q9NRW3,Q9NUJ1,Q9H0P0,Q13126,O60725,P04062 6 +Skeletal muscle organ development 0.3842182929377554 0.7385381309435128 0.4601875047858983 1.0 0.956915294750558 25 P17844,Q7Z406,Q9BRT2,O75955,Q92841,P16989,Q16539,Q00535,P41440,Q9BYT8,P50402,P51114 12 +Synaptic vesicle exocytosis 0.4108788632973219 0.7375687077035402 0.4607765768354159 1.0 0.9569181611669944 17 P35080,Q4J6C6,Q00535,Q9P253,P16615,O95721,Q06787,P0DP25 8 +Tricarboxylic acid cycle 0.391848216452258 0.7362380707775203 0.4615858271725712 1.0 0.9575855383567063 22 P48735 1 +Regulation of cysteine type endopeptidase activity involved in execution phase of apoptosis 0.6967237751728312 0.731780844402476 0.4643023427115536 1.0 0.9575855383567063 2 Q13177 1 +Striated muscle cell differentiation 0.3541909114445644 0.7316596869746361 0.4643763077205478 1.0 0.9575855383567063 43 O75844,Q99523,Q8IV08,P09493,P31749,P41440,P67809 7 +Regulation of dendritic spine development 0.4389153567504393 0.7314159153914015 0.4645251469194942 1.0 0.9575855383567063 13 Q9UQB8 1 +Sensory perception 0.3602623697585573 0.7312461121096613 0.4646288391014836 1.0 0.9575855383567063 40 P50897,P11047,Q15555,Q9Y6M9,Q9H6K4,O43924,Q00535,Q01469,P53611,P42574,O60313,Q14108 12 +Protein localization to synapse 0.4619889835805941 0.730311459049354 0.4651998254010436 1.0 0.9575855383567063 11 Q9UQB8 1 +Peptidyl proline hydroxylation to 4 hydroxy l proline 0.5377184720219341 0.7302674371875574 0.4652267282900229 1.0 0.9575855383567063 6 P13674 1 +Cellular amide metabolic process 0.2847032349210628 0.7286584777622725 0.4662105979442368 1.0 0.9584434706261932 487 P50897,Q969T7,O15217,Q16739,Q9UJ14,Q9Y2R0,Q9BRP8,O95197,Q9NSE4,Q96PZ0,Q92945,Q9UIQ6,Q7Z739,P34897,P16989,P30153,Q14103,Q5T653,Q9Y5A9,Q06787,Q567V2,O60506,P17900,Q96G23,Q9Y619,P00374,Q7Z7F7,P55010,Q9UMR5,Q5VV42,O75503,P41440,P67809,P51114,P04062,P62857,P78417,Q9H2D1,Q14011,P82675,O75874,P34896,P67812,P31749,P42892,Q9NYY8,Q8NCC3,Q9NZ08,Q9NZ01,Q9BYT8,O95470,O95563,O15270,P51116,Q16799,Q8N983,P08670,P55786,Q15363,P98179,P06730,Q15120,O75976,Q99805 64 +Muscle structure development 0.3399412558568527 0.7276732472407405 0.4668136306975385 1.0 0.9587247684218264 92 P62942,O75844,Q7KZ85,Q99523,P09493,Q8IV08,P31749,P16989,P41440,P67809,P51114 11 +Skeletal muscle cell differentiation 0.4808423260420793 0.7248476285225839 0.4685455127940776 1.0 0.959599978605972 8 Q9BYT8,P50402,Q9BRT2,Q92841 4 +Negative regulation of blood circulation 0.7170775706554327 0.7246261977357127 0.4686813825725493 1.0 0.959599978605972 3 P16615,P05023 2 +Regulation of cell communication by electrical coupling 0.7161755862898301 0.7215583162506194 0.4705660747520532 1.0 0.9600553218472616 3 P0DP25,P30626 2 +Srp dependent cotranslational protein targeting to membrane 0.4631670968260599 0.7195695531446574 0.4717900638373713 1.0 0.9613878388053576 10 Q15629 1 +Response to toxic substance 0.34585730988247 0.7195349582841707 0.4718113708458076 1.0 0.9613878388053576 46 P08183,P07099,Q15165,P78417,Q6DKJ4,P00374,O95831,P30048,P07196 9 +Mononuclear cell differentiation 0.3481050791176649 0.7178370298153605 0.4728577782426311 1.0 0.962915776703558 45 O96005,O00625,P04083,P49327,P24390,P04062 6 +Hematopoietic stem cell homeostasis 0.6341079373466253 0.7175603240643208 0.473028428745363 1.0 0.962961321715482 4 Q14157 1 +Positive regulation of glucose import 0.5565049953941766 0.7152431010295289 0.4744588404848775 1.0 0.9634570700777968 5 P31749 1 +Positive regulation of fatty acid metabolic process 0.7135364835242237 0.7126018208633926 0.4760921846951058 1.0 0.9649633730992564 3 P04083 1 +Regulation of reproductive process 0.3923798417812693 0.7101240062899086 0.4776272407141899 1.0 0.9663785530073042 20 Q7Z739,Q07021,P35453,Q13043,Q9H6S0,P30153,Q9Y5A9,Q15645,P15291 9 +Rac protein signal transduction 0.4467649265202851 0.7094390047731602 0.4780520901329521 1.0 0.9663785530073042 12 P46108,Q9P035,Q9Y2I1 3 +Male sex differentiation 0.3760963586399393 0.7064658143369544 0.4798985048237076 1.0 0.9663785530073042 27 Q02790,Q15392 2 +Long chain fatty acyl coa biosynthetic process 0.5034402683858595 0.7024178848753367 0.4824185949115369 1.0 0.967325033641575 7 Q9NZ01 1 +Cellular respiration 0.347432620379561 0.701541502222028 0.482965143766904 1.0 0.9673969586829388 105 P04062,Q9BSK2,O43676,Q15070,P20674,O75964,O75874,Q9UDW1,O75306,P34897,O75438,O95168,Q9H3K2,P48735,P00846,P14406,O14949 17 +Very long chain fatty acid metabolic process 0.459518283274216 0.7013987867724241 0.4830541789181928 1.0 0.9673969586829388 10 Q9NZ01,Q15067 2 +Peptide transport 0.3653343907398883 0.70023063496733 0.4837832827220503 1.0 0.9674541457872732 35 Q8N183,P53985,Q16836,Q03518,P04083,Q8N5M9,O95563 7 +Photoreceptor cell development 0.6289462203116254 0.6990568422090955 0.4845165082966662 1.0 0.9674541457872732 4 Q15555 1 +Regulation of translation at synapse modulating synaptic transmission 0.6288717672511108 0.6987907871603719 0.4846827868865437 1.0 0.9674541457872732 4 P06730 1 +Regulation of response to endoplasmic reticulum stress 0.383877814887833 0.6980083821045163 0.4851719520671396 1.0 0.9674541457872732 23 P46379,P57088,O95881,Q92905,Q04323,O60313 6 +Regulation of binding 0.3426839354204289 0.6973540020883777 0.4855812803011909 1.0 0.9674541457872732 99 P62942,P19474,O75844,P31749,P09601,O75503,P41440 7 +Mannosylation 0.5293960312859451 0.696387833101506 0.4861859805283997 1.0 0.9674541457872732 6 Q6ZXV5,O43505,O75340 3 +Positive regulation of ubiquitin protein transferase activity 0.4615682156445058 0.6962992531565766 0.4862414408011948 1.0 0.9674541457872732 9 Q16763,Q9BTE7 2 +Meiosis i cell cycle process 0.3919866862985134 0.6950144650623025 0.4870462365005594 1.0 0.9674541457872732 19 O94901,P46379,Q92791,Q9BTX1,Q15645 5 +Positive regulation of protein k63 linked ubiquitination 0.6865043582807283 0.6943690951925867 0.4874507697360695 1.0 0.9674541457872732 2 O00571 1 +Neutral amino acid transport 0.5288826084646164 0.694306281046052 0.487490152826453 1.0 0.9674541457872732 6 Q96QD8,Q96NB2 2 +Mrna modification 0.4195002814327815 0.6928923884468909 0.4883770867398593 1.0 0.9674541457872732 14 Q96PZ0,Q15007,Q99729 3 +Regulation of cyclin dependent protein kinase activity 0.3802276773033598 0.690297631791039 0.4900070368547271 1.0 0.967631177983784 24 O95373,P53350,P78536,Q96SZ6,O75832,O94992,P25054,P31749,P42771,P42574 10 +Negative regulation of cellular catabolic process 0.338746048220292 0.6866941085472811 0.4922755103286795 1.0 0.9690035266380757 95 Q9Y2S7,Q9NQ11,O15118,P16989,Q14103,O60506,P98175,P09601,Q99729,P67809,Q14011,P31749,P30536,Q9H2J4,P10619,P46379,Q92804,P06730,P35637 19 +Action potential 0.3888011393209152 0.6863904875776393 0.492466901355272 1.0 0.9690035266380757 20 P30626,Q12955,Q99996,P16615,P0DP25,Q06787,P05023,P04062 8 +Muscle cell apoptotic process 0.4306035179050239 0.6856276726172112 0.4929479266668686 1.0 0.9690035266380757 13 O95140,P09601 2 +Fucose metabolic process 0.7053643843201205 0.6850609504628951 0.4933054602811022 1.0 0.9690035266380757 3 Q9BTY2 1 +Regulation of erad pathway 0.4993514232021676 0.684645875080318 0.4935674110794474 1.0 0.9692249070305208 7 P46379 1 +Oligodendrocyte development 0.4590185542418478 0.6838517923894034 0.494068757841104 1.0 0.9693300644773806 9 Q13144,P10909,Q92542,Q9NR50,P49770 5 +Positive regulation of cyclin dependent protein kinase activity 0.5262083290971473 0.6834809397665299 0.494302990182573 1.0 0.9694967134538296 6 P31749,P78536 2 +Transepithelial transport 0.7036814428222484 0.6794268381758934 0.4968674495570595 1.0 0.9695707268384752 3 P08183 1 +Negative regulation of response to wounding 0.4707019173406462 0.6774441031139989 0.4981242239726331 1.0 0.9695707268384752 8 Q96G23 1 +Reactive oxygen species metabolic process 0.3459554436302675 0.6770096779120345 0.4983998139839265 1.0 0.9695707268384752 44 Q9BSK2,P00374,Q15067,P42785,P30536,Q15120 6 +Leukocyte apoptotic process 0.3829598142668002 0.6753734460830111 0.4994385317190724 1.0 0.9695707268384752 22 P14174,P78536,Q13546,P31749,P04083,P42771,P49327,P42574,P24390 9 +Regulation of intrinsic apoptotic signaling pathway 0.3396532802273156 0.6736250137314371 0.5005497462172883 1.0 0.9695707268384752 54 P14174,O00571,P45880,Q9UL15,P61978,Q8N2F6,P31749,P16989,O76024,Q96K76,O95881,O60341,Q9Y3D6,P10909,Q7LG56,O60313 16 +Protein k11 linked ubiquitination 0.4568993609851718 0.6735251250507001 0.5006132699343611 1.0 0.9695707268384752 9 Q16763,Q9UJX6,Q9UJX3 3 +Neuromuscular process 0.3716435187180966 0.6735228726800943 0.5006147023676846 1.0 0.9695707268384752 27 P78417,P17900,O75844,Q8IZL8,Q6Y7W6,P07196,P04062 7 +N terminal protein amino acid acetylation 0.5232860339196272 0.6716849679892081 0.5017842730242366 1.0 0.9695707268384752 6 Q86UY6 1 +Positive regulation of mitotic cell cycle phase transition 0.356698651821683 0.6708371157523512 0.5023243001166047 1.0 0.9695707268384752 38 O00571,Q96DY7,P78536,Q9UJX4,P31749,P11802,P04083,Q9UJX3,P31350,Q7LG56 10 +Lipid phosphorylation 0.6795912233243011 0.669410599809264 0.5032335918260855 1.0 0.9695707268384752 2 Q9NRA0 1 +Cellular response to virus 0.3702513752928726 0.6692118186017274 0.5033603681949639 1.0 0.9695707268384752 28 O00571,P35232,Q07021,Q9NUD5,O43657,Q9Y4E8,Q16539,Q3LXA3,Q06787,O15111 10 +Bone remodeling 0.4954840464688692 0.6678985821023138 0.5041983325460868 1.0 0.9695707268384752 7 Q92791 1 +I kappab phosphorylation 0.5222894523089545 0.6676704182983387 0.5043439968063397 1.0 0.9695707268384752 6 P31749 1 +Actin mediated cell contraction 0.4044394282381927 0.6639072272144403 0.5067496903328252 1.0 0.9722281759497174 16 P16615,Q9UM22,P09493 3 +Regulation of notch signaling pathway 0.4547056477433282 0.6628545761123509 0.5074236960756182 1.0 0.9722281759497174 9 Q9Y5A9 1 +Muscle cell proliferation 0.3701240234485752 0.6622986445036835 0.5077798453804618 1.0 0.9722281759497174 27 Q5VZE5,P09493,P31749,P09601,O95140 5 +G0 to g1 transition 0.618577396018721 0.6622464635844959 0.5078132810431208 1.0 0.9722281759497174 4 Q7LG56 1 +Regulation of g0 to g1 transition 0.618577396018721 0.6622464635844959 0.5078132810431208 1.0 0.9722281759497174 4 Q7LG56 1 +Regulation of lipid localization 0.3707397047068275 0.6617651923870694 0.5081217168422145 1.0 0.9722281759497174 26 P31749,P30536,Q8WTV0 3 +Face development 0.4542613561059597 0.6606959335345333 0.5088073321661215 1.0 0.9726085257726652 9 O95470 1 +Regulation of programmed necrotic cell death 0.4539680515628939 0.6592713415756061 0.5097215419845864 1.0 0.9726085257726652 9 P12235,P16989,Q13510 3 +Regulation of viral transcription 0.4934310981385251 0.6590343106760257 0.5098737362752335 1.0 0.9726085257726652 7 P19474 1 +Regulation of lipoprotein particle clearance 0.4666118353840462 0.6584397113785018 0.5102556249517125 1.0 0.9726085257726652 8 Q92945,P61978 2 +Negative regulation of peptidase activity 0.3534851177953078 0.6574490644294938 0.5108922121651429 1.0 0.9726085257726652 39 Q15041,P04080,Q15392,P31749,P07858,P30086,P30048,Q96K76 8 +Autophagy of nucleus 0.6171148174540666 0.6570949295466638 0.5111198789911713 1.0 0.9726085257726652 4 Q5MNZ6,Q7Z3C6 2 +Positive regulation of mammary gland epithelial cell proliferation 0.6759843703035688 0.6565072809271852 0.5114977844202162 1.0 0.9726085257726652 2 Q92766 1 +Positive regulation of phospholipase activity 0.4659811446385219 0.6555156808968862 0.5121357937605056 1.0 0.9726085257726652 8 Q9Y263,P40616,P18085,P20248 4 +Blood vessel morphogenesis 0.3221685181031278 0.6534283139387103 0.5134801902275645 1.0 0.9726085257726652 78 P42785,P31749,P09601,Q96AY3,Q9NZ08,Q9H2J4,O95470 7 +Er nucleus signaling pathway 0.4126135009515794 0.6533678442216456 0.5135191639181351 1.0 0.9726085257726652 14 Q96A33,P16615,Q15363,P57088 4 +Regulation of cell morphogenesis involved in differentiation 0.368881368426023 0.6531266438954213 0.5136746366692675 1.0 0.9726085257726652 27 P46108,Q9UQB8 2 +Negative regulation of microtubule polymerization or depolymerization 0.4075489274648924 0.6519139847626553 0.5144566627486504 1.0 0.9728833919306162 15 Q02790 1 +Organic hydroxy compound transport 0.3577133037920494 0.6516177183861862 0.5146478146205173 1.0 0.9729615453116854 36 Q86Y82,Q9UHB6,P53985,Q9P260,Q9H4L5,Q8WTV0,O15118,P30536,P10909 9 +Rna destabilization 0.337655276918597 0.6505226413628874 0.5153546815359118 1.0 0.9732907460228796 53 Q7Z739,Q969T7,Q13148,Q92945,P11940,Q6Y7W6,Q9HCE1,Q14103,Q9BYJ9,Q96B26,Q9Y5A9,P67809,O60506 13 +Positive regulation of muscle cell apoptotic process 0.4911867322706018 0.6493648712062497 0.5161025643704005 1.0 0.973678948240771 7 P17655,P98175,O95140 3 +Regulation of gene silencing by rna 0.3829026587045807 0.6473917037893625 0.5173784638816632 1.0 0.973678948240771 20 Q9HAV4,O75844,Q06787,Q01085,P51114 5 +Regulation of mitochondrial fission 0.4485943679450754 0.6472992701114508 0.517438273826528 1.0 0.973678948240771 10 Q9NUQ9 1 +Protein localization to axon 0.6729786594529618 0.6458188759437365 0.5183966620480851 1.0 0.9738502794040186 2 Q12955 1 +Complement activation 0.6136212327778863 0.6448325209676038 0.5190357245753467 1.0 0.974230674198691 4 P10909,Q07021 2 +Response to steroid hormone 0.320540443007597 0.6443764438045515 0.5193313559095072 1.0 0.974230674198691 77 O95831,Q969T9,O75874,O15173,Q02790,P30536,P07196,Q9P253,P06730,Q9UBS8,P04083,P04062 12 +Mitotic nuclear membrane organization 0.5155862430599695 0.6407812324980828 0.5216648279787608 1.0 0.9750552851173392 6 Q6NUK4,Q86XL3 2 +Response to glucagon 0.6711752329425935 0.639434546563183 0.5225402810411242 1.0 0.9750552851173392 2 P20248 1 +Schwann cell differentiation 0.488646682402136 0.6384493368150459 0.5231812235619313 1.0 0.9750552851173392 7 P31749,P11047 2 +Glutamine metabolic process 0.4097763051168375 0.6371478778999408 0.5240285247541734 1.0 0.9750552851173392 14 Q06210,P17812,Q06203,Q9NRF8 4 +Positive regulation of smooth muscle cell apoptotic process 0.6109244198413887 0.6354090040464087 0.5251616971602484 1.0 0.9752359340459402 4 P98175,O95140 2 +Engulfment of apoptotic cell 0.6693718064322227 0.6330721260031605 0.5266865437882573 1.0 0.9756172203464424 2 P84095 1 +Sulfur compound metabolic process 0.3386493596133321 0.6328884004814133 0.5268065231273731 1.0 0.9756172203464424 101 P50897,O15217,P78417,Q9UJ14,O43505,O75874,Q8NCH0,Q9UMR5,Q13126,Q9NZ01,O60725,O95563 12 +Polyol metabolic process 0.3653345880856616 0.6325204434530789 0.5270468541806959 1.0 0.9756676941418012 28 P00374,P35270,P04062 3 +Negative regulation of cysteine type endopeptidase activity 0.3785404104655587 0.6311657874787363 0.5279321293723915 1.0 0.9764714463526944 21 Q15392,Q15041 2 +Response to dexamethasone 0.4479506027669722 0.6301290043670306 0.5286101844960653 1.0 0.9765400670534052 9 P06730 1 +Regulation of membrane lipid distribution 0.6092953515830194 0.629734783368145 0.5288681209394017 1.0 0.9765400670534052 4 P08183 1 +Lipid translocation 0.6092953515830194 0.629734783368145 0.5288681209394017 1.0 0.9765400670534052 4 P08183 1 +Intrinsic apoptotic signaling pathway by p53 class mediator 0.380222848470424 0.6297296443295402 0.5288714838045621 1.0 0.9765400670534052 20 P14174,P46379,Q7LG56,P61978 4 +Lymphocyte homeostasis 0.4444469868324068 0.6268936435307444 0.5307289542265354 1.0 0.977442073856472 10 P14174,P31749,P49327 3 +Cellular response to cadmium ion 0.4853818420235254 0.6244641888294176 0.5323227815956137 1.0 0.9790156170155524 7 P31749,P09601,P28482 3 +Positive regulation of dna dependent dna replication 0.5326248874981181 0.6229494190208452 0.5333177612261966 1.0 0.9797211883647092 5 Q04837,P46100 2 +Wound healing 0.3227350385968809 0.6217720627872536 0.5340917589168104 1.0 0.9806027374627556 69 P46108,P38435,P09493,Q8WTV0,P42785,P09601,Q96AY3,P49257 8 +Vitamin d metabolic process 0.6857289550824294 0.6201879318537045 0.5351340658427712 1.0 0.9813836523288424 3 P04062 1 +Positive regulation of cell projection organization 0.3225668144891195 0.6199041458005812 0.5353208961431708 1.0 0.9813836523288424 69 Q32P28,Q9UQB8,O14641,P42858,Q15555,P11233,P07196,Q9UJX6,Q06787,Q14108,Q9Y639 11 +Establishment of protein localization 0.2901908580970077 0.617707853703618 0.5367679340131135 1.0 0.9813836523288424 550 Q8N183,Q9NS69,O43731,A6NIH7,P24390,Q99595,Q32P28,Q8N4Q1,O60725,Q15629,P10619,Q8N4H5,O95563,Q9Y282,P46379,O95831,Q03518,Q15363,Q14168,P43307,Q5JRX3,P50897,Q16836,Q99523,Q9HD20,Q9UMY4,Q14108,O95373,O43752,Q16850,Q15070,Q15041,Q969T9,P31749,P30536,P49257,Q9P2W9,O95391,O14925,P55786,Q9BTX1,Q96JB2,O95140,Q92614,Q9NQ11,P53365,Q9P253,Q92973,O43823,Q86YV9,Q96L92,P18085,Q9H1Z9,Q4J6C6,O95721,Q9HAV4,Q9BVK6,P11233,P84085,O15027,P20645,O95429,O14737,P04083,Q8N5M9,O15118,O15397,Q8WWC4,Q9Y6Y8,P53985,Q92783,Q9Y5X3,O96028,Q96PC5,O95613,O95071,Q9BUN8,P52789,P09132,O75340,Q9Y512,P02786,Q9Y2T2,Q00535,P61020,P48643,Q9Y5M8 87 +Skeletal system morphogenesis 0.3907923634057152 0.613465524795288 0.5395685715553697 1.0 0.984534505108337 17 O95470 1 +Regulation of glucose transmembrane transport 0.4167806159255634 0.6101198591211503 0.5417824122677337 1.0 0.9855381778420508 13 Q01469,P31749,Q16539,P52789 4 +Thioester biosynthetic process 0.3731507198427517 0.6086026267972681 0.5427878629292375 1.0 0.9860070174794252 22 P50897,O95563,Q9UMR5,Q9NZ01 4 +Camera type eye morphogenesis 0.4553782009407424 0.6066392010246346 0.5440903788909499 1.0 0.9872374742994772 8 O95140,Q15555 2 +Leukocyte mediated immunity 0.3328077132695238 0.6061783857939731 0.5443963038961548 1.0 0.9875166473468238 54 O96028,Q9UQ84,Q9NRA0,P78536,Q7KZ85,P02786,P46108,P09601,Q8N5M9,P04439,P01889,Q96FZ2,Q9NUQ9 13 +Negative regulation of cholesterol metabolic process 0.6612563871355595 0.6047206406151203 0.5453646312035456 1.0 0.98859036662374 2 O94905 1 +Serine family amino acid metabolic process 0.3993303800010862 0.6039133195699535 0.5459012728456187 1.0 0.988611649085714 15 P00374,P34896 2 +Regulation of defense response to virus 0.3943648949603002 0.6035366000911371 0.5461517750079361 1.0 0.988611649085714 16 O43657 1 +Regulation of innate immune response 0.332164734792538 0.5998511043662678 0.5486054713092936 1.0 0.9907241186547698 54 Q7Z739,P19474,Q9Y3Z3,P46108,P04439,O94992,Q9Y5A9,Q9NUD5,Q9Y4E8,Q9NZ08,P01889,Q96PK6,O60828 13 +Positive regulation of cytokine production 0.3240083170377404 0.5993234146151398 0.5489572367941982 1.0 0.9908804493340534 66 P14174,O15111,Q9NRA0,P78536,P04439,Q13546,P15260,Q9NUD5,P04083,P09601,P41440,P10909,O60828,Q9NUQ9 14 +Postsynapse to nucleus signaling pathway 0.65945296062519 0.598484259345497 0.5495168587517916 1.0 0.9908804493340534 2 P52292 1 +Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 0.3528163664474011 0.5983780498857442 0.5495877085347951 1.0 0.9908804493340534 35 O96028,Q9UQ84,P78536,Q7KZ85,P02786,P04083,P04439,P01889,Q96FZ2,Q9NUQ9 10 +Regulation of autophagy 0.3386098752091988 0.5983462606577241 0.5496089152418846 1.0 0.9908804493340534 105 P21796,P19474,Q93050,O75844,P12235,Q9BXS4,Q9NQ11,P07602,P31749,P30536,P09601,Q9Y487,P06730,P10619,O15270,P04062 16 +Positive regulation of lipase activity 0.4413119663046853 0.5981809307447626 0.5497192139188996 1.0 0.9908804493340534 9 Q9Y263,P40616,P18085,P20248 4 +Negative regulation of sister chromatid cohesion 0.6785929043896486 0.5971104064637971 0.5504336705045936 1.0 0.9910900292061798 3 P41227,P46100 2 +Cardiac muscle contraction 0.3766236834055463 0.5952622305193247 0.5516681984532161 1.0 0.9910900292061798 19 P78417,P09493,P16615,Q99996,P10253,P0DP25,P05023 7 +Protein polyubiquitination 0.3319904793059365 0.5951248435462495 0.5517600232646949 1.0 0.9910900292061798 53 P19474,O00571,Q9H000,Q15386,O95071,Q9UJX4,Q96FW1,Q9UIQ6,P52888,P55786,Q9UJX6,Q9UJX3,Q9UBS8,Q16763 14 +Ribosomal small subunit export from nucleus 0.478306795321355 0.5943427022241584 0.5522829231090729 1.0 0.9910900292061798 7 Q86U38 1 +Astrocyte development 0.4782543828169153 0.5941205502021125 0.5524314869787681 1.0 0.9910900292061798 7 P08670,P11047 2 +Regulation of myotube differentiation 0.5245917221458873 0.5925511754750047 0.553481562550691 1.0 0.9910900292061798 5 Q9BYT8 1 +Positive regulation of dna binding transcription factor activity 0.3366476312852534 0.5922913822950037 0.5536554856098408 1.0 0.9910900292061798 44 P19474,O14641,P02786,Q13546,P60900,P31749,P30048,Q92905,P41440,O15111 10 +Midbrain development 0.3760234924732345 0.5913918889596438 0.5542578737620905 1.0 0.9910900292061798 19 Q16352,P0DP25,O15027,O14949 4 +Long term synaptic potentiation 0.4236685597374094 0.5886706759808277 0.5560822127409866 1.0 0.9910900292061798 12 Q14168,Q9Y639 2 +Mucopolysaccharide metabolic process 0.4361473846505717 0.5863145436523584 0.5576641593874152 1.0 0.9910900292061798 10 Q8NCH0 1 +Regulation of low density lipoprotein particle clearance 0.4762285341397089 0.5855455566141556 0.5581809437703957 1.0 0.9910900292061798 7 Q92945,P61978 2 +Positive regulation of cell cell adhesion 0.3582205172364099 0.5854708644563326 0.5582311517424143 1.0 0.9910900292061798 29 P31749,P04083,Q9NUQ9,P41440 4 +Collagen catabolic process 0.5961489854990545 0.5844748303285531 0.5589008943869134 1.0 0.9910900292061798 4 P07858 1 +Regulation of response to biotic stimulus 0.3169141546904603 0.5844126956267706 0.558942687268537 1.0 0.9910900292061798 71 P14174,P19474,O75844,P46108,Q9NUD5,O43657,Q9NZ08,Q9Y5A9 8 +Hormone mediated signaling pathway 0.3313856574450585 0.5832693973736045 0.5597119603326319 1.0 0.9910900292061798 47 Q969T9,P42785,O15173,Q02790,Q9P253 5 +Proteolysis 0.3377989668605117 0.5832418157092089 0.5597305251140654 1.0 0.9910900292061798 405 Q16740,O75832,Q15392,Q9UIQ6,P42785,O94888,Q9Y4E8,Q04323,P42574,Q6ZXV5,Q9UL15,Q96FW1,P30086,O75503,Q99797,P49721,P28072,Q9HD42,P19474,Q9H000,Q8TCT8,Q15386,O95630,Q9HB40,Q99436,P42892,Q9NZZ3,Q92905,Q9NZ08,Q9H3G5,P10619,Q16763,P46379,Q9NR28,Q96KC8,O95831,Q9UJX4,Q96A33,Q9UHG3,P52888,P10909,Q9BWJ5,Q5JRX3,Q96A26,P28070,Q9UJ14,O75844,Q9BXS4,Q13043,P28074,Q96F07,Q9Y3D6,Q9UMY4,P17655,O00571,P53350,Q9Y263,Q8IWV7,P20618,Q9UBV2,P48147,P04062,Q15041,P31749,Q9H2J4,P54725,P38159,P55786,Q9UJX3,O75976,P25786,Q9NQ11,P34897,P60900,Q4J6C6,P67812,Q969V3,P07858,Q9UBS8,P49327,Q9BYT8,O14737,Q96FZ2,Q06787,Q92783,Q92820,Q9BXI6,Q96K76,P09960,Q7Z2K6,Q9BXK5,Q9BUN8,Q96TA2,O75340,P78536,P04080,P02786,Q9H8M7,P30048,Q00535,Q86TI2 101 +Regulation of response to osmotic stress 0.5214599421416488 0.5808005848653227 0.5613748608598208 1.0 0.9910900292061798 5 P08183,P16989 2 +Positive regulation of protein tyrosine kinase activity 0.5212693995576086 0.5800875496525931 0.5618555793222821 1.0 0.9910900292061798 5 P78536,O14641 2 +Negative regulation of intracellular signal transduction 0.3412647150952807 0.5798539158331802 0.5620131352726772 1.0 0.9910900292061798 111 P14174,O75832,P16989,P30153,O00571,Q9UL15,Q8IWV7,P30086,O95881,Q96K76,O60341,Q8N2F6,Q7LG56,Q9NUQ9,P04062,Q9H000,P45880,Q99829,Q14152,Q13546,P57105,O95630,P31749,Q16539,O75340,O60313,Q07021,O43657,O76024,P10909,O95140 31 +Regulation of membrane permeability 0.37415363367272 0.5793491658540665 0.5623535970562357 1.0 0.9910900292061798 19 P12235,P45880 2 +Regulation of mrna splicing via spliceosome 0.3200266484006074 0.5790776987875554 0.5625367470353622 1.0 0.9910900292061798 68 Q13242,Q06787,Q15007,P61978,Q9BWF3,P98175,Q92841,Q8NDT2,Q8IY67,Q9UHX1,Q13247,P51114,O75525,P22626,Q14011,P62995,Q07666,P09651,P26368,P08621,P51116,P38159,P98179 23 +Mitotic g2 m transition checkpoint 0.3797838520932425 0.5790676084258252 0.5625435552285154 1.0 0.9910900292061798 18 Q9Y619 1 +Positive regulation of posttranscriptional gene silencing 0.3947808808298943 0.5775070912628182 0.5635969496490167 1.0 0.991569790287052 15 Q9HAV4,Q06787,Q01085,P51114 4 +Peroxisome proliferator activated receptor signaling pathway 0.5202555375000013 0.5762972454455115 0.5644142844119564 1.0 0.9919638330098092 5 Q15120 1 +Positive regulation of transporter activity 0.3614443269644493 0.575327678624089 0.5650697055719465 1.0 0.9922583856520428 25 P08183,P78417,P42858,Q03164,Q9Y4C2,Q00535,P0DP25 7 +Regulation of cardiac muscle cell action potential 0.4734904826408087 0.5739927626657533 0.5659726987777165 1.0 0.9922583856520428 7 P16615,P0DP25 2 +Response to xenobiotic stimulus 0.3127599154433902 0.5737901090215766 0.5661098427534368 1.0 0.9922583856520428 75 P07099,O15217,P78417,Q16836,P17812,Q96DG6,P09601,O43169 8 +Phosphatidylglycerol acyl chain remodeling 0.6513375413285267 0.5707213365060497 0.5681885532064044 1.0 0.9937561175659548 2 Q92604 1 +Negative regulation of apoptotic signaling pathway 0.3212691447580424 0.5697346463589681 0.5688576874445719 1.0 0.994390800071346 66 P14174,O00571,P45880,Q9UL15,P42858,Q13546,O75832,P31749,P10909,P16989,P09601,Q96K76,O95881,Q8N2F6,Q9H3K2,Q7LG56,O60313 17 +Schwann cell development 0.4973466018000796 0.5687323600338917 0.5695377836201714 1.0 0.9947763224393203 6 P31749,P11047 2 +Regulation of fibroblast migration 0.4350535888115477 0.5682800347502817 0.569844833610218 1.0 0.9949350613739943 9 P31749 1 +Immunoglobulin production involved in immunoglobulin mediated immune response 0.3880015876439641 0.5657061904069397 0.5715935263446381 1.0 0.9949350613739943 16 O96028,Q9UQ84,Q96FZ2,Q7KZ85 4 +Somatic diversification of immunoglobulins involved in immune response 0.3880015876439641 0.5657061904069397 0.5715935263446381 1.0 0.9949350613739943 16 O96028,Q9UQ84,Q96FZ2,Q7KZ85 4 +Positive regulation of lipid localization 0.3874686836741789 0.5625500805183778 0.5737412925098746 1.0 0.9949350613739943 16 Q8WTV0 1 +Regulation of protein polymerization 0.3213565957014187 0.5603769125653859 0.5752223759480268 1.0 0.9949350613739943 65 P45880,Q9NUQ9,Q9UQB8 3 +Regulation of intrinsic apoptotic signaling pathway in response to dna damage 0.4280155764790734 0.5601199756596962 0.5753976060603114 1.0 0.9949350613739943 11 P14174,P10909,Q96K76,P61978 4 +Carnitine metabolic process 0.4950316563202562 0.5597183822313252 0.5756715419511287 1.0 0.9949350613739943 6 P23786 1 +Regulation of production of molecular mediator of immune response 0.3555176470395778 0.5596396779846761 0.5757252351021962 1.0 0.9949350613739943 28 P14174,O96028,Q9NRA0,Q7KZ85,P02786,P09601,Q96FZ2 7 +Post embryonic animal morphogenesis 0.6477306883077876 0.5585454418243567 0.5764719834138294 1.0 0.9949350613739943 2 P46100 1 +Regulation of pigmentation 0.6477306883077765 0.5585454418243183 0.5764719834138556 1.0 0.9949350613739943 2 Q96AX1 1 +Cellular aldehyde metabolic process 0.3657064060285946 0.5582999380945326 0.576639587209532 1.0 0.9949350613739943 22 P48735 1 +Activation of gtpase activity 0.3652838983245323 0.5554563330175595 0.5785825702201461 1.0 0.9949350613739943 22 O60343,P46108,Q66K14,Q8TC07,Q0IIM8,Q9BXI6,Q9UJX6 7 +Placenta development 0.3559625927024069 0.5544674145203291 0.5792590003750138 1.0 0.9949350613739943 26 P62993,P31749,P07858,Q15363,P28482,P35613 6 +T cell mediated immunity 0.4294344910223057 0.5537728313865657 0.5797343240229882 1.0 0.9949350613739943 10 P01889,P04439,Q9NUQ9,O15400 4 +Cerebellar cortex formation 0.5868842576419696 0.55318607238146 0.5801360029448381 1.0 0.9949350613739943 4 P04062 1 +Leukocyte migration 0.3281848015469272 0.5527002001239045 0.5804687163017976 1.0 0.9949350613739943 48 P14174,P35613,P78536,P46108,P31749,P04083,P09601,Q8N5M9,P28482,P15291,P04062 11 +Positive regulation of sphingolipid biosynthetic process 0.6645017851425421 0.5524061776106284 0.5806700990811182 1.0 0.9949350613739943 3 Q9NRA0 1 +Regulation of dna templated transcription in response to stress 0.4290984808433199 0.5521511297428882 0.5808448137245352 1.0 0.9949350613739943 10 P09601 1 +Protein n linked glycosylation 0.3698740136443466 0.5518776406131581 0.5810321884667207 1.0 0.9949350613739943 19 Q86YN1,Q06210,Q14165,Q9HC07,P26572,O75340,Q13724,P15291 8 +Regulation of secretion 0.332444750044101 0.5518210287043487 0.5810709783382406 1.0 0.9949350613739943 102 Q8N183,P14174,Q92614,Q16836,Q9NQ11,Q9P253,Q06787,P53985,Q32P28,Q92783,Q4J6C6,Q9Y5X3,P09601,P0DP25,P00367,Q9H4A6,Q16850,P11233,O95563,Q9NRA0,P04083,Q00535,Q8N5M9,P16615 24 +Regulation of intrinsic apoptotic signaling pathway by p53 class mediator 0.4261381625778895 0.5508859598041211 0.5817118527427003 1.0 0.9949350613739943 11 P14174,Q7LG56,P61978 3 +Response to thyroid hormone 0.4677135673672756 0.5497632816960113 0.5824817463204592 1.0 0.9949350613739943 7 P04062 1 +Eye photoreceptor cell development 0.6633178941126647 0.5487054742772809 0.5832075887744699 1.0 0.9949350613739943 3 Q15555 1 +Vesicle docking involved in exocytosis 0.4252496374654086 0.5465234662302559 0.5847061617112232 1.0 0.9949350613739943 11 Q7Z6M1 1 +Response to peptide 0.3312468037061718 0.5464510090128737 0.5847559550282795 1.0 0.9949350613739943 101 O60343,Q9BSK2,P62993,P43490,Q9UQB8,P46108,Q16836,Q99523,P31749,Q9Y5X3,P04083,P07196,P08670,P35613 14 +Iron ion transport 0.4278707521133436 0.5462317511194407 0.5849066432321126 1.0 0.9949350613739943 10 O15173,P02786 2 +Positive regulation of neutrophil migration 0.5112390666879805 0.5428730537303157 0.5872172100593944 1.0 0.9949350613739943 5 O00429,Q07021,Q8NE86 3 +Positive regulation of granulocyte chemotaxis 0.5112390666879805 0.5428730537303157 0.5872172100593944 1.0 0.9949350613739943 5 O00429,Q07021,Q8NE86 3 +Intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator 0.4146969361357107 0.5425115321009121 0.5874661652824735 1.0 0.9949350613739943 12 P14174,P46379 2 +Regulation of macrophage migration 0.583592872755753 0.5422002758911093 0.5876805452693312 1.0 0.9949350613739943 4 P14174 1 +Regulation of macrophage chemotaxis 0.583592872755753 0.5422002758911093 0.5876805452693312 1.0 0.9949350613739943 4 P14174 1 +Reactive oxygen species biosynthetic process 0.4238376558921347 0.5396013084061724 0.5894720141010756 1.0 0.9949350613739943 11 Q9BSK2 1 +Response to hormone 0.3776812107140632 0.5381565550380697 0.5904689707032245 1.0 0.9949350613739943 190 Q16739,P62993,P43490,Q16836,Q99523,Q15392,O15118,P42785,Q9P253,O43823,Q9Y5X3,O43347,P09601,P07196,Q96PK6,P04062,P09960,Q9BSK2,Q9UQB8,Q969T9,O75874,P31749,P07858,Q02790,P30536,Q9UBS8,P35613,O60343,O95831,P46108,Q8IZL8,O15173,P04083,P06730 34 +Regulation of sphingolipid biosynthetic process 0.5823643854455702 0.5381180027169464 0.5904955844822666 1.0 0.9949350613739943 4 Q9NRA0 1 +Amino acid betaine metabolic process 0.4644342747928142 0.5361015744155129 0.591888352077212 1.0 0.9949350613739943 7 P23786 1 +Positive regulation of nervous system development 0.3360250192699554 0.5360221264845201 0.5919432584457571 1.0 0.9949350613739943 41 P30536,Q9UJX6,Q9UQB8,Q9Y639 4 +Axoneme assembly 0.6590321308216879 0.5353835496611533 0.5923846630199208 1.0 0.9949350613739943 3 Q15555 1 +Positive regulation of nitric oxide metabolic process 0.488706176836034 0.5352539041461737 0.5924742965522991 1.0 0.9949350613739943 6 P31749 1 +Transmission of nerve impulse 0.4639946638294751 0.5342754157182767 0.5931509985250667 1.0 0.9949350613739943 7 P04062 1 +Tumor necrosis factor mediated signaling pathway 0.3822736663199059 0.5318893369584206 0.5948026429286406 1.0 0.9949350613739943 16 P78536,Q8TCT8,Q13546,P49327,O15111 5 +Regulation of signal transduction by p53 class mediator 0.3400650658398506 0.5306218651303685 0.5956808407271641 1.0 0.9949350613739943 38 P14174,P61978,O75844,O75832,O94992,P31749,O14757,Q8N2F6,Q7LG56 9 +Positive regulation of neurogenesis 0.3369820840889745 0.5299724618087657 0.5961310241330959 1.0 0.9949350613739943 40 P30536,Q9UJX6,Q9UQB8,Q9Y639 4 +Digestive system process 0.3905834682874772 0.5286410768736873 0.5970544594446667 1.0 0.9949350613739943 14 Q16739,Q8WTV0 2 +Negative regulation of tumor necrosis factor superfamily cytokine production 0.5070212542694283 0.5274211542868704 0.5979011564090513 1.0 0.9949350613739943 5 P30536 1 +Protein targeting to lysosome 0.4012597647812087 0.52659661085619 0.5984737460272558 1.0 0.9949350613739943 13 Q9Y2T2,Q14108,P20645,Q99523 4 +Positive regulation of brown fat cell differentiation 0.6559697923982626 0.5259378006236917 0.5989314238892585 1.0 0.9949350613739943 3 Q92766 1 +Negative regulation of programmed necrotic cell death 0.5064172325896356 0.5252183454686155 0.5994314131765608 1.0 0.9949350613739943 5 P12235,P16989 2 +Negative regulation of necrotic cell death 0.5064172325896356 0.5252183454686155 0.5994314131765608 1.0 0.9949350613739943 5 P12235,P16989 2 +Regulation of endoplasmic reticulum unfolded protein response 0.4373388355735486 0.5249105841394612 0.599645351309676 1.0 0.9949350613739943 8 P57088,Q92905 2 +Positive regulation of cell cycle g1 s phase transition 0.3563394203929396 0.5229265215741468 0.601025387531668 1.0 0.9949350613739943 24 Q96DY7,P04083,P31749 3 +Necrotic cell death 0.365340196294202 0.5229255169814174 0.6010260866502202 1.0 0.9949350613739943 19 Q13546,P12235,P16989,P30536,P49327,Q13510 6 +Organelle fusion 0.3248736808385975 0.5215181283207277 0.602005880335116 1.0 0.9949350613739943 48 O60343,P02786,Q9NX63,Q9NQ11,P04083,Q9P253,O43752,O95721,O95140,Q9Y6C9,O60313 11 +Negative regulation of cell morphogenesis involved in differentiation 0.6542393265183373 0.5206277530390238 0.6026261120595033 1.0 0.9949350613739943 3 Q9ULV4,O43707 2 +Pyramidal neuron differentiation 0.5770114538438114 0.5204480460958911 0.6027513300602583 1.0 0.9949350613739943 4 O14949 1 +Positive regulation of amine transport 0.5767329488962216 0.5195340470249648 0.6033883766757746 1.0 0.9949350613739943 4 Q15041 1 +Positive regulation of amino acid transport 0.5767329488962216 0.5195340470249648 0.6033883766757746 1.0 0.9949350613739943 4 Q15041 1 +Glycerophospholipid metabolic process 0.321235089401197 0.5188240313124987 0.6038834581258703 1.0 0.9949350613739943 60 Q9NPH0,Q8WTV0,Q8NCC3,P42356,P35790,Q8N2K0 6 +Response to tumor necrosis factor 0.3323034131601844 0.5187556812034531 0.6039311270809118 1.0 0.9949350613739943 42 O15111,P78536,Q8TCT8,Q13546,P28482,O95429,P31749,P16989,P49327,Q13510,P42574,P04062 12 +Positive regulation of nuclear cell cycle dna replication 0.635707844905324 0.5187253005489854 0.6039523157982407 1.0 0.9949350613739943 2 P46100 1 +Cellular carbohydrate catabolic process 0.3645992148698936 0.5182096846886481 0.6043119784092352 1.0 0.9949350613739943 19 Q9NUJ1 1 +Histone h4 r3 methylation 0.6351067027352002 0.5167663731647013 0.6053192565637504 1.0 0.9949350613739943 2 Q99873 1 +Negative regulation of autophagy 0.3505033774787487 0.5151952562744601 0.6064165835749895 1.0 0.9949350613739943 26 Q9Y2S7,P31749,P30536,P09601,P06730,P10619 6 +Negative regulation of nitric oxide metabolic process 0.5751050753667657 0.51420245168914 0.6071104538465695 1.0 0.9949350613739943 4 Q92945,P30536 2 +Fatty acid derivative biosynthetic process 0.3739385222665903 0.5110928932004715 0.6092860120641477 1.0 0.9949350613739943 17 P50897,Q9UJ14,Q9UMR5 3 +Regulation of macrophage activation 0.4808888919755386 0.5053759924967128 0.6132947775555271 1.0 0.9949350613739943 6 P14174 1 +Intestinal absorption 0.4192105429906873 0.5047631025286204 0.6137252341247188 1.0 0.9949350613739943 10 Q8WTV0 1 +Negative regulation of cell substrate junction organization 0.5720300751879729 0.5041820633618559 0.6141334436196739 1.0 0.9949350613739943 4 Q9ULV4,Q9P258,O75122 3 +Humoral immune response 0.3970268460047681 0.5041050886272981 0.6141875312502627 1.0 0.9949350613739943 13 Q9UQ84 1 +Multicellular organismal signaling 0.3555331532249828 0.5029708439830273 0.6149847710904965 1.0 0.9949350613739943 23 O75844,P16615,P0DP25,Q06787,P04062 5 +Regulation of mitochondrial membrane potential 0.3606099909569158 0.5018693959192174 0.6157593942271586 1.0 0.9949350613739943 20 P31749,Q9BSK2 2 +Negative regulation of intrinsic apoptotic signaling pathway in response to dna damage 0.4319804504867421 0.5010431358372884 0.6163407651798418 1.0 0.9949350613739943 8 P14174,P10909,Q96K76 3 +Antiviral innate immune response 0.499398315282797 0.4998120711818869 0.6172074101098923 1.0 0.9949350613739943 5 P35232,Q99623,Q9NVI7,Q92667 4 +Negative regulation of transcription regulatory region dna binding 0.6296964232040757 0.4992789512180851 0.6175828814903819 1.0 0.9949350613739943 2 P30626 1 +Negative regulation of circadian rhythm 0.6296964232040735 0.4992789512180782 0.6175828814903868 1.0 0.9949350613739943 2 P23246 1 +Cellular oxidant detoxification 0.3597963105264616 0.496629832405895 0.6194501117723852 1.0 0.9964600014490635 20 P00374,P78417 2 +Regulation of cardiac muscle contraction 0.4054598360859928 0.4955518293567313 0.620210646013081 1.0 0.9965224270934472 12 P16615,P78417,P0DP25 3 +Macrophage proliferation 0.569344882745338 0.4954873026626816 0.6202561826781203 1.0 0.9965224270934472 4 P28482,P04062 2 +Cellular response to peptide 0.3068190256683065 0.4947920900365287 0.620746888451384 1.0 0.9965711479859798 76 O60343,Q9BSK2,P43490,Q9UQB8,P31749 5 +Pyrimidine ribonucleoside triphosphate biosynthetic process 0.430447190878343 0.4942522743507339 0.6211280259895455 1.0 0.996578015899968 8 P17812 1 +Muscle cell migration 0.39514179920412 0.4941339956357152 0.6212115504100817 1.0 0.996578015899968 13 P46108,P09493 2 +Rna interference 0.4166907148730605 0.4927973497554718 0.6221557835317209 1.0 0.997125831213985 10 O94992,Q9HAV4 2 +Negative regulation of catabolic process 0.3308586648275385 0.4910436479705958 0.623395576644407 1.0 0.997125831213985 107 Q9Y2S7,Q9NQ11,O15118,P16989,Q14103,Q9UMY4,O60506,P98175,P09601,Q99729,P67809,Q16850,Q14011,P31749,P30536,Q9H2J4,P10619,P46379,Q92804,P06730,P35637 21 +Cellular component assembly involved in morphogenesis 0.3553080222212431 0.4887310608486769 0.6250321105482457 1.0 0.9977688589757135 22 Q9NR77 1 +Negative regulation of protein catabolic process 0.3284717249912263 0.4850926439080741 0.6276106298784563 1.0 0.9979697353811532 42 Q16850,P46379,Q9H2J4,P10619,Q9UMY4 5 +Positive regulation of fibroblast migration 0.5660209356976453 0.4847973670828915 0.6278200905763427 1.0 0.9979697353811532 4 P31749 1 +Protein demethylation 0.4149842819596822 0.4847214739032064 0.6278739318111826 1.0 0.9979697353811532 10 Q9H6W3,Q8NB78 2 +Glial cell development 0.3560339139558065 0.4822902943531683 0.6295997410074503 1.0 0.9987651722617472 21 P11047,P15260,P08670,P31749,Q00535,P10909,Q92542,P49770 8 +Microtubule organizing center localization 0.392539142493965 0.4804150362785627 0.6309323046401882 1.0 0.9993516228152552 13 O94901,Q9Y613,Q8TD16,Q8WXH0,Q99996,Q9UH99 6 +Plus end directed organelle transport along microtubule 0.6236850015028601 0.4801578778554529 0.6311151358601779 1.0 0.999381051518165 2 Q9Y496 1 +Establishment of mitochondrion localization 0.402313882416991 0.4797059522969134 0.6314364948324613 1.0 0.999477138515897 12 Q9UBK9,P07196,O60313 3 +Stem cell proliferation 0.3916955576221799 0.4759806931944721 0.6340881326348349 1.0 1.0 13 Q9Y5A9,P04062 2 +Serine family amino acid catabolic process 0.6390955461908727 0.4750447329176191 0.6347550895742851 1.0 1.0 3 P34896 1 +Regulation of establishment of protein localization to mitochondrion 0.3629739474790276 0.4749238451581876 0.6348412547512536 1.0 1.0 18 O95429,P55786,P49257 3 +Sprouting angiogenesis 0.3768134676348096 0.474662847351968 0.6350273030454692 1.0 1.0 15 P31749,P09601 2 +Response to corticosteroid 0.3439402765389542 0.4745694184560743 0.6350939080078859 1.0 1.0 28 O95831,P04818,P04083,P07196,P06730,P0DP25,P42574,P04062 8 +Macropinocytosis 0.6387489532022299 0.4740207981243866 0.6354850760925332 1.0 1.0 3 Q9BZG1 1 +Atp biosynthetic process 0.3546583286219856 0.4733262448448544 0.635980440765765 1.0 1.0 21 P00846 1 +Regulation of gliogenesis 0.4008109600557412 0.4721643764647709 0.6368094648444318 1.0 1.0 12 Q96G23 1 +Release of sequestered calcium ion into cytosol by endoplasmic reticulum 0.4915571669800865 0.4718659994268615 0.6370224382689296 1.0 1.0 5 P78417 1 +Histone arginine methylation 0.6378824931141756 0.4714649368902471 0.6373087530538197 1.0 1.0 3 Q86X55 1 +Negative regulation of cell substrate adhesion 0.4141753037930519 0.470361375296248 0.6380968546799068 1.0 1.0 9 O75122,O14936,Q9ULV4,P42771 4 +Intracellular receptor signaling pathway 0.3109879922152711 0.4690868321276109 0.6390075708791325 1.0 1.0 67 Q969T9,Q9NUD5,O43657,P42785,Q02790,Q9P253,Q9UBS8,Q15120 8 +Cellular homeostasis 0.3520596052185976 0.4673495712617522 0.6402497958024522 1.0 1.0 144 P62942,Q8N183,P50897,Q9HD20,Q9NQ11,Q9Y487,Q8WWC4,Q93050,P42858,P09601,O75503,O75880,Q8N511,P78417,P62995,P52789,Q9HC07,O95563,Q9Y639,P02786,P16615,P30048,Q00535,Q8N5M9,P28482,Q15120 26 +Regulation of voltage gated calcium channel activity 0.4900395097171396 0.4665128972826978 0.640848418025102 1.0 1.0 5 Q06787,Q00535 2 +Mitochondrial protein processing 0.4705010116373078 0.4663378547489649 0.6409736867620233 1.0 1.0 6 Q96TA2,Q99797 2 +Endosome to lysosome transport 0.3549631749299481 0.4656370669704208 0.6414753061168113 1.0 1.0 20 Q99523,Q96L92,Q9P253 3 +Regulation of exocytosis 0.3203872404522032 0.4629523507775702 0.6433985218476108 1.0 1.0 45 Q92783,P11233,Q9NQ11,Q4J6C6,P04083,P09601,Q9P253,Q00535,P16615,P0DP25,Q06787 11 +Response to progesterone 0.4465077475884857 0.4627387259569692 0.6435516563983179 1.0 1.0 7 Q969T9 1 +Response to fungus 0.4464212423006814 0.4623905889310621 0.6438012469462979 1.0 1.0 7 P46108,Q8N5M9 2 +Receptor mediated endocytosis 0.3128169288465721 0.4605187114696407 0.6451439439125046 1.0 1.0 64 P50897,P62993,P61978,P02786,Q7Z6M1,Q9UBF8,P20645,Q5VW38,P41440,Q06787,Q14108 11 +Positive regulation of dopamine receptor signaling pathway 0.6173730087165631 0.4604440495814356 0.6451975228942819 1.0 1.0 2 O14744 1 +Regulation of dopamine receptor signaling pathway 0.6173730087165631 0.4604440495814356 0.6451975228942819 1.0 1.0 2 O14744 1 +Copii coated vesicle budding 0.3553463116216354 0.4597424392797427 0.6457011035344187 1.0 1.0 19 Q15363,O15027,Q92734 3 +Regulation of histone h3 k14 acetylation 0.6335262536972184 0.4587005907954267 0.6464491897366385 1.0 1.0 3 Q969T9 1 +Macrophage migration 0.4875867333695377 0.4579010800426477 0.6470235109126963 1.0 1.0 5 P14174 1 +Macrophage chemotaxis 0.4875867333695377 0.4579010800426477 0.6470235109126963 1.0 1.0 5 P14174 1 +Carbohydrate transport 0.3601636659717934 0.4577569637274442 0.6471270579170572 1.0 1.0 18 Q01469,P31749,Q99523 3 +Positive regulation of proteolysis involved in cellular protein catabolic process 0.3176211609235999 0.4563501075424395 0.6481382371163478 1.0 1.0 46 Q6ZXV5,Q9H000,P53350,P46379,P53634,O75832,P54725,P48729,P31749,Q9UII2,O60826,Q9UBS8,P10909,Q06787,P04062 15 +Pyrimidine deoxyribonucleoside monophosphate metabolic process 0.5570251769898125 0.4562875197297059 0.6481832372649381 1.0 1.0 4 P34896 1 +Pyrimidine deoxyribonucleoside monophosphate biosynthetic process 0.5570251769898125 0.4562875197297059 0.6481832372649381 1.0 1.0 4 P34896 1 +Dtmp metabolic process 0.5570251769898125 0.4562875197297059 0.6481832372649381 1.0 1.0 4 P34896 1 +Endoplasmic reticulum calcium ion homeostasis 0.4217417354582502 0.4560444566459385 0.64835800990938 1.0 1.0 8 Q9Y3D6,P16615,Q96A33 3 +Regulation of cell aging 0.397495724929483 0.4555966594877417 0.6486800457379349 1.0 1.0 12 P14174,O75844 2 +Arachidonic acid secretion 0.6322707537758838 0.4550486547918778 0.6490742357796508 1.0 1.0 3 P14174 1 +Regulation of lipid metabolic process 0.3130394888227356 0.4548770006718061 0.6491977300278178 1.0 1.0 63 Q96G23,O75844,Q9UBM7,O75874,Q8WTV0,Q9H6K4,P07602,P31749,P30536 9 +Calcium ion export across plasma membrane 0.6321515683014736 0.4547026051947674 0.6493232063835963 1.0 1.0 3 P0DP25 1 +Excretion 0.4866278210093927 0.4545478018581428 0.6494345946645512 1.0 1.0 5 P09601 1 +Regulation of mitochondrial fusion 0.5563912064000993 0.4543022080889372 0.6496113270123991 1.0 1.0 4 Q9Y6C9 1 +Protein localization to lysosome 0.3643735595242997 0.4540121630842555 0.6498200724211456 1.0 1.0 17 Q9NQ11,Q99523,Q14108,P20645 4 +Cell junction disassembly 0.5560686859655164 0.45329345456007 0.650337445418744 1.0 1.0 4 Q15555 1 +Protein o linked glycosylation via serine 0.6309929261374443 0.4513442723049383 0.6517414411604254 1.0 1.0 3 Q10471 1 +Photoreceptor cell differentiation 0.4856649963308609 0.4511885790977034 0.6518536403088984 1.0 1.0 5 Q15555 1 +Response to zinc ion 0.4653566630265933 0.4473090079059668 0.6546519639478097 1.0 1.0 6 Q9NQ11,P30536 2 +Defense response to symbiont 0.3115213682881209 0.4468645333665456 0.654972873118167 1.0 1.0 64 P19474,O75844,Q9NUD5,O43657,Q9H0P0 5 +Negative regulation of alpha beta t cell activation 0.6290212971169263 0.4456535343293116 0.6558475337696958 1.0 1.0 3 P04083 1 +Glycerolipid metabolic process 0.3077821640438589 0.4449046242034866 0.6563886807277686 1.0 1.0 68 Q9NPH0,Q8WTV0,Q8NCC3,P42356,P35790,Q8N2K0 6 +Response to ketone 0.3162701772146672 0.4438909737700123 0.6571214107357535 1.0 1.0 46 O43823,O95831,Q969T9,P31749,Q13126,P30536,P06730,P04062 8 +Nucleoside bisphosphate biosynthetic process 0.339621008325193 0.4431459883069961 0.657660143157333 1.0 1.0 28 P50897,O95563,Q9UMR5,Q9NZ01 4 +Regulation of stress granule assembly 0.5527819548872209 0.4430614668312491 0.6577212756697852 1.0 1.0 4 Q9UN86,P54646,Q13283 3 +Positive regulation of extrinsic apoptotic signaling pathway 0.4077363477591975 0.4408347032568185 0.6593326680626928 1.0 1.0 9 P30154,Q13546,P30153,Q13043 4 +Behavior 0.3096471410733212 0.440263251577085 0.6597464532075763 1.0 1.0 85 P50897,P04062,P53985,P17900,O75844,P18085,P42858,P04080,O15118,P31749,Q6Y7W6,P30536,Q00535,P06730,P28482,P42574,Q8N2K0,Q9Y639 18 +Cellular response to estrogen stimulus 0.5507700150529828 0.4368417309157552 0.6622261324142571 1.0 1.0 4 Q8IZL8,Q969T9 2 +Nervous system process 0.3310490191315903 0.4362397204265261 0.6626628119514906 1.0 1.0 114 P50897,O75844,P11047,Q8N0X7,P42574,Q06787,Q14108,O00264,P17900,P18085,P42858,P07196,P04062,P78417,Q9UQB8,Q9Y6M9,Q9H6K4,P31749,P53611,O60313,Q9Y639,Q15555,Q8IZL8,Q6Y7W6,O43924,Q00535,Q14168,Q01469,P28482 29 +Negative regulation of cell projection organization 0.3366473534843172 0.4355359621724324 0.6631734415308186 1.0 1.0 31 Q96G23,Q9NR77,Q02790,Q00535,Q8N0X7,P08670 6 +Deoxyribonucleotide biosynthetic process 0.4064336073751222 0.4349047161310735 0.6636315912239203 1.0 1.0 9 Q7LG56 1 +Aminoglycan catabolic process 0.4803870431424913 0.4329147481011806 0.6650767052927804 1.0 1.0 5 P04066,P54802,P08236 3 +Glycosaminoglycan catabolic process 0.4803870431424913 0.4329147481011806 0.6650767052927804 1.0 1.0 5 P04066,P54802,P08236 3 +Icosanoid biosynthetic process 0.3833119057736408 0.4322613366080854 0.6655514843316088 1.0 1.0 13 P14174,Q9UJ14,P04083,Q01469,P09960 5 +Smooth muscle cell apoptotic process 0.4610381346742799 0.4315005719997614 0.6661044367966618 1.0 1.0 6 O95140 1 +Cellular response to hormone stimulus 0.3439236769501893 0.4310274351837808 0.666448422094486 1.0 1.0 135 Q16739,P62993,P43490,P42785,Q9P253,O43823,Q9BSK2,Q9UQB8,Q969T9,P31749,P07858,Q02790,Q9UBS8,O60343,O95831,P46108,Q8IZL8,O15173,P04083,P06730 20 +Positive regulation of lymphocyte mediated immunity 0.3556939703042102 0.430622760518214 0.6667426889297705 1.0 1.0 18 O96028,P02786,P04439,Q96FZ2,Q9NUQ9 5 +L serine metabolic process 0.4791393868192859 0.4286304646611056 0.6681921715369958 1.0 1.0 5 P34896 1 +Negative regulation of nuclear division 0.3455802059367868 0.4245708131067786 0.671149573533228 1.0 1.0 22 Q96DY7,Q96EA4,P53350,O43683,Q9H900,O60566,O14757,Q15645 8 +Collagen biosynthetic process 0.5462231312101666 0.4229103122607934 0.6723606986694235 1.0 1.0 4 Q92791 1 +Negative regulation of viral process 0.346506143163568 0.4206094266920845 0.6740403090512854 1.0 1.0 21 P19474,Q9NRW3 2 +Extracellular matrix disassembly 0.4012271034061931 0.4204948148022364 0.6741240165156521 1.0 1.0 10 P41440 1 +Response to interleukin 4 0.4358406589593153 0.4202828367306888 0.6742788465707401 1.0 1.0 7 P49327 1 +Exocytic process 0.3488141263346869 0.4189955827871612 0.675219360594637 1.0 1.0 19 Q7Z6M1,Q9P253 2 +Response to mineralocorticoid 0.4129828220810697 0.4182512909139164 0.6757633985950022 1.0 1.0 8 O95831,P07196 2 +Response to muramyl dipeptide 0.47602292328778 0.4179897819719232 0.6759545880278255 1.0 1.0 5 P08670,Q9NZZ3 2 +Intermembrane lipid transfer 0.4570259256777614 0.4169548538562915 0.6767114298606829 1.0 1.0 6 P61916,P30536 2 +Locomotion involved in locomotory behavior 0.6029455966336086 0.4168548884245745 0.6767845517857729 1.0 1.0 2 Q96QK1 1 +Fatty acyl coa biosynthetic process 0.3896126695598004 0.4166021570487513 0.6769694313267876 1.0 1.0 12 P50897,Q9UMR5 2 +T cell differentiation 0.3358483343019376 0.4158655179263193 0.6775084129303846 1.0 1.0 28 O96005,O15360,P04083,P24390,P04062 5 +Regulation of striated muscle contraction 0.3793923619734583 0.4120554508916441 0.6802987803763041 1.0 1.0 13 P78417,Q99996,P16615,P0DP25,P05023 5 +3 utr mediated mrna stabilization 0.4011186283602813 0.4108734498239031 0.6811653315829305 1.0 1.0 9 P07910,P98175,P16989,Q16539,Q13148 5 +Endocrine system development 0.3790977201319055 0.410542949548891 0.6814077040158935 1.0 1.0 13 P31749,P04083,P30536 3 +Animal organ morphogenesis 0.3165062750097215 0.4100104606872732 0.6817982739845643 1.0 1.0 97 P62942,P35613,P53701,O14641,O75844,P11047,Q15555,Q8IZL8,P09493,Q15363,O95470,O95140,P04062 13 +Negative regulation of signal transduction in absence of ligand 0.4331710729807985 0.4098142225588146 0.681942232251556 1.0 1.0 7 P31749 1 +Regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion 0.5414575771274058 0.4084993547961834 0.6829071041331491 1.0 1.0 4 P78417 1 +Production of molecular mediator of immune response 0.3279064716483243 0.4083850433553684 0.6829910122868506 1.0 1.0 36 P14174,O96028,Q9UQ84,Q9NRA0,Q7KZ85,P02786,P09601,P04439,Q96FZ2 9 +Peptidyl arginine methylation to asymmetrical dimethyl arginine 0.6154188987666981 0.4072444280652739 0.6838284737904337 1.0 1.0 3 Q86X55 1 +Positive regulation of peptidase activity 0.3178568734901629 0.4070168767894756 0.6839955928621437 1.0 1.0 43 Q9BXK5,Q9NR28,O95831,O14737,Q9BXI6,P49327,Q96A26 7 +Regulation of cell projection organization 0.3381123926842784 0.4050057006492573 0.6854733206338841 1.0 1.0 129 Q9NR77,Q8N0X7,Q9UJX6,O60828,Q06787,Q14108,Q9UL15,Q32P28,Q96G23,P42858,Q8TC07,P10586,Q9HA65,P07196,Q9BXI6,Q15428,P51114,Q9UQB8,P11233,P31749,Q02790,Q9HCE1,Q7L576,Q9Y639,P51116,O14641,Q15555,P46108,Q66K14,Q00535,P08670 31 +Regulation of necrotic cell death 0.3778637690874696 0.4042186726088156 0.6860519238739142 1.0 1.0 13 Q13546,P12235,P16989,P30536,Q13510 5 +Amino sugar metabolic process 0.3976277386485731 0.4039733036795798 0.6862323506049219 1.0 1.0 10 O60502 1 +Protein folding 0.3274706624361395 0.4025296883019245 0.6872942437872596 1.0 1.0 113 P62942,P26885,Q32P28,O95429,Q8N4Q1,Q02790,O75718,Q13451,Q9H2J4,P49257,O60925 11 +Lysosomal protein catabolic process 0.3988100268152774 0.4005196071615907 0.68877384496115 1.0 1.0 9 Q9NQ11,P04062 2 +Protein catabolic process in the vacuole 0.3988100268152774 0.4005196071615907 0.68877384496115 1.0 1.0 9 Q9NQ11,P04062 2 +Positive regulation of ion transmembrane transport 0.3325579394265525 0.3997145444759067 0.6893667782721451 1.0 1.0 30 P08183,P78417,Q15041,P42858,Q9Y4C2,Q00535,P0DP25 7 +Regulation of heart contraction 0.3400439321176105 0.3991593472263529 0.6897757954500434 1.0 1.0 23 P78417,O75844,P09493,P16615,P0DP25 5 +Histone deubiquitination 0.4515890541702976 0.3974709017039312 0.6910202401106418 1.0 1.0 6 Q9BWJ5 1 +Regulation of response to external stimulus 0.3432785023006575 0.3961403218906461 0.6920015137054587 1.0 1.0 139 P14174,Q7Z739,P28070,P25786,O75844,O15360,Q9Y4E8,Q9Y5A9,O60828,Q96G23,Q9UMX5,P60900,P10586,P80303,O15164,Q96PK6,Q9NUQ9,P04062,P19474,Q9H000,O94992,Q9NUD5,Q9NZ08,Q8N2K0,P78536,P46108,O43657,P04083,P28482 29 +Glial cell migration 0.376224303336514 0.3958414984983882 0.6922219606344953 1.0 1.0 13 O94901,Q96N66,Q96G23,P30536,Q00535 5 +B cell mediated immunity 0.3447068381668044 0.3936309257864526 0.6938535453563481 1.0 1.0 19 Q96FZ2,Q9UQ84,O96028,Q7KZ85 4 +Cd40 signaling pathway 0.4685761645360778 0.3929270894640788 0.6943733329599304 1.0 1.0 5 O15360,P35232 2 +Hormone transport 0.3243929931533742 0.3907752976107151 0.6959633356694352 1.0 1.0 37 Q8N183,P53985,Q16836,P04083,Q8N5M9,O95563 6 +Positive regulation of histone ubiquitination 0.53457305742308 0.3880368402305453 0.6979887708894581 1.0 1.0 4 Q5VTR2,O60341 2 +Response to vitamin a 0.6075955435157375 0.3858564669321289 0.6996029728985083 1.0 1.0 3 P04818 1 +Positive regulation of phospholipid metabolic process 0.4480890761360264 0.385071578859407 0.7001843842394067 1.0 1.0 6 P17655,Q05655,O95573,Q9UJZ1,Q9UHD1 5 +Ribonucleoside triphosphate biosynthetic process 0.3297718082569315 0.3840377227806559 0.7009504885423734 1.0 1.0 31 P00846,O75964 2 +Replicative senescence 0.5328951825264153 0.3831153304728274 0.7016342531864819 1.0 1.0 4 O14757 1 +Synaptic vesicle membrane organization 0.4655091130174015 0.3827588880137859 0.7018985469036232 1.0 1.0 5 O43760,O95721 2 +Membrane depolarization during cardiac muscle cell action potential 0.5909227532311376 0.3821876261945553 0.7023221993307278 1.0 1.0 2 Q12955 1 +Regulation of membrane depolarization during cardiac muscle cell action potential 0.5909227532311376 0.3821876261945553 0.7023221993307278 1.0 1.0 2 Q12955 1 +Regulation of membrane depolarization during action potential 0.5909227532311376 0.3821876261945553 0.7023221993307278 1.0 1.0 2 Q12955 1 +Negative regulation of neuron death 0.3094555109737789 0.3813543807732264 0.7029403067718589 1.0 1.0 46 P50897,Q9UMX5,Q01105,Q9NQ11,P31749,P09601,P04062 7 +Lymphocyte migration 0.3629824861308024 0.3778262908710942 0.7055596416237098 1.0 1.0 14 P31749,P04062 2 +Histone h3 k9 acetylation 0.4246897565083046 0.3770035130226796 0.7061709942083121 1.0 1.0 7 Q03164,Q9NRA0,O14757 3 +Myeloid leukocyte migration 0.3365865953225911 0.3763721770566023 0.7066402274313006 1.0 1.0 23 P14174,P04083,Q8N5M9,P35613 4 +Ether metabolic process 0.393244904847049 0.3757824819427446 0.707078612292541 1.0 1.0 9 P07099,P49327,O15228 3 +Adaptation of signaling pathway 0.5879170423805262 0.3737677807352693 0.7085770922052033 1.0 1.0 2 P50570 1 +G protein coupled receptor internalization 0.5879170423805262 0.3737677807352693 0.7085770922052033 1.0 1.0 2 P50570 1 +Aminoglycan metabolic process 0.350418211790182 0.372459362870837 0.7095508627216072 1.0 1.0 17 P04066,O43505,Q7LGA3,Q8NCH0,Q9NX62,P54802,P08236 7 +Regulation of ire1 mediated unfolded protein response 0.4443959953713603 0.3721145194713675 0.7098075863830771 1.0 1.0 6 P57088 1 +Cerebral cortex radially oriented cell migration 0.4019249849988337 0.3715820950379905 0.71020402215237 1.0 1.0 8 O94901,Q00535,Q96N66 3 +Telencephalon glial cell migration 0.4019249849988337 0.3715820950379905 0.71020402215237 1.0 1.0 8 O94901,Q00535,Q96N66 3 +Neuron projection arborization 0.4231832464000987 0.3712498198962011 0.7104514693218777 1.0 1.0 7 O14641 1 +Activation of phospholipase d activity 0.6014300088689615 0.369379742874759 0.7118446949032302 1.0 1.0 3 P18085 1 +Oocyte maturation 0.4608456231923509 0.3674771376291725 0.7132631422959954 1.0 1.0 5 P30153 1 +Regulation of atp metabolic process 0.3281236598103032 0.3671437970170235 0.7135117596491529 1.0 1.0 30 P14406,Q9BSK2,P30536 3 +Nuclear body organization 0.4423713511886901 0.3650676425737983 0.7150609139194404 1.0 1.0 6 Q9BPY3,Q8NC51,Q9BUR4,P78362,O75312 5 +Cellular nitrogen compound catabolic process 0.3609020506882046 0.3649491554733656 0.7151493603601164 1.0 1.0 182 Q7Z739,Q969T7,Q9H773,Q92945,P30519,P16989,Q14103,Q9BQG2,Q9Y5A9,O60506,P98175,P09601,Q99729,P51530,P67809,P51114,Q14011,P31749,Q9NYY8,Q13126,Q9NRW3,P51116,Q92804,O95831,Q6PGP7,P08670,P62312,Q9BRP8,P35637 29 +Ether biosynthetic process 0.4599530722816795 0.3645775106145923 0.7154268049439529 1.0 1.0 5 P49327,O15228 2 +Cellular response to ether 0.5995456359175261 0.3644123343221877 0.7155501263142234 1.0 1.0 3 Q9H4A6 1 +Negative regulation of nuclear transcribed mrna catabolic process nonsense mediated decay 0.5986759002263995 0.3621305654822128 0.7172544635805673 1.0 1.0 3 Q99729 1 +Bone morphogenesis 0.4202440931148907 0.3600918791536071 0.7187784255205383 1.0 1.0 7 Q7Z3C6,Q9NX62,O75844 3 +Eye morphogenesis 0.3878783819226845 0.3598850889666638 0.7189330682493655 1.0 1.0 10 O95140,Q15555 2 +Negative regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway 0.4408291573187409 0.3597273651705222 0.7190510256754561 1.0 1.0 6 O60313 1 +Cellular response to estradiol stimulus 0.4408194682635632 0.359693889764315 0.7190760619011978 1.0 1.0 6 O95831 1 +Positive regulation of protein secretion 0.3280347571841826 0.357915966927551 0.7204062013448043 1.0 1.0 27 Q9NV70,Q9H4A6,Q92614,P49755,P30626,Q9NQ11,Q9H4A5,O00429,P00367,O95563 10 +Mrna 3 splice site recognition 0.4381148290837953 0.3503868084515429 0.7260484250303321 1.0 1.0 6 O95391 1 +Cell proliferation in forebrain 0.5212030075188001 0.3495622094890722 0.7266672761375137 1.0 1.0 4 Q96N67,Q15154,Q15058 3 +Regulation of nervous system development 0.3014981251465356 0.3494179045462743 0.7267755935277123 1.0 1.0 65 Q96G23,Q9UQB8,P31749,P30536,Q9UJX6,Q9Y5A9,Q9Y639 7 +Negative regulation of organic acid transport 0.5935377492745065 0.3487932975471749 0.7272444955895456 1.0 1.0 3 P31749 1 +Regulation of ruffle assembly 0.3963403122398903 0.3484995139095667 0.727465078813371 1.0 1.0 8 Q9ULV4,Q7L576,P84095,P35080 4 +Regulation of fc gamma receptor signaling pathway involved in phagocytosis 0.5785993387436198 0.3483172727812452 0.7276019232980795 1.0 1.0 2 Q9UKG1 1 +Response to interleukin 12 0.5785993387436172 0.3483172727812381 0.7276019232980848 1.0 1.0 2 P07237 1 +Membrane depolarization during action potential 0.5911004209260269 0.3425531102313633 0.7319346825123736 1.0 1.0 3 Q12955,Q04917 2 +Regulation of b cell activation 0.3451609975536851 0.3423685482271624 0.7320735547573316 1.0 1.0 17 P14174,O96028,Q7KZ85,P02786,Q96FZ2 5 +Regulation of neuron projection arborization 0.5181963046319994 0.341150181015574 0.7329905256696336 1.0 1.0 4 O14641 1 +Response to nicotine 0.4353240304764705 0.3408624737993583 0.7332071163570626 1.0 1.0 6 P28482,P09601 2 +Positive regulation of synapse assembly 0.5755936278930045 0.3403219415537865 0.7336140952828503 1.0 1.0 2 Q9H2P0 1 +Protein targeting to membrane 0.3144732519233261 0.3389972082497526 0.7346118332735205 1.0 1.0 40 O60725,P43307,Q15629,P46379 4 +Regulation of mitotic cytokinesis 0.5893852795662393 0.3381957079695054 0.7352157100499805 1.0 1.0 3 Q9Y2S7 1 +Fatty acyl coa metabolic process 0.3518761832012536 0.3371134419469266 0.7360313847219946 1.0 1.0 15 P50897,Q9UMR5 2 +Cobalamin metabolic process 0.5740907724676966 0.3363642345002585 0.7365962165368714 1.0 1.0 2 Q99707 1 +Regulation of protein maturation 0.3729612713321676 0.3363583549976744 0.7366006496911206 1.0 1.0 12 Q9BXS4 1 +Peroxisome fission 0.4507523682719449 0.3351753266522838 0.7374928331066275 1.0 1.0 5 Q9Y3D6,O00429,P40855 3 +Cellular response to steroid hormone stimulus 0.303848106986993 0.3337851446957335 0.7385416939921909 1.0 1.0 58 O95831,Q969T9,O15118,O15173,Q02790,P04083,Q9P253,P06730,Q9UBS8 9 +Cellular copper ion homeostasis 0.5875375728875909 0.333533023137708 0.7387319662147731 1.0 1.0 3 O75880 1 +Oxidative dna demethylation 0.5728884881274452 0.3332173867900365 0.7389701946159812 1.0 1.0 2 Q9C0B1 1 +Dendritic spine development 0.3281834690038682 0.3321017581626044 0.7398124225828497 1.0 1.0 24 Q9UQB8,Q06787,P18085 3 +Activation of innate immune response 0.3311716556246153 0.3316536359116874 0.7401508140166948 1.0 1.0 22 O94992,Q96PK6,Q9NUD5 3 +Copper ion homeostasis 0.5146560293295465 0.3313625549321602 0.7403706455167751 1.0 1.0 4 O75880 1 +Intestinal lipid absorption 0.5862873477442131 0.3303967414882384 0.741100203344569 1.0 1.0 3 Q16739 1 +Tetrahydrofolate interconversion 0.4115363151830778 0.3275790935005146 0.74322993144132 1.0 1.0 7 P34896 1 +Negative regulation of cell population proliferation 0.3115807984253621 0.3269875509610765 0.7436773010180397 1.0 1.0 100 Q96DY7,Q32P28,Q96G23,Q15392,P09493,Q9NR77,P30536,P09601,O95140 9 +Regulation of glucocorticoid metabolic process 0.5695822061917662 0.3246527463201135 0.7454439018774046 1.0 1.0 2 P05023 1 +Cellular response to carbohydrate stimulus 0.3229549141223072 0.3225150890930074 0.7470625085113767 1.0 1.0 27 Q8N183,P62995,Q8N5M9,Q15120,O95563 5 +Mammary gland epithelium development 0.3899155111803865 0.3223840401764121 0.7471617734524951 1.0 1.0 8 P31749,P28482 2 +Cellular response to vascular endothelial growth factor stimulus 0.4296240851359927 0.3216674526547318 0.7477046373986611 1.0 1.0 6 P31749 1 +Protein o linked mannosylation 0.5110309940410129 0.3214742511032175 0.7478510221870864 1.0 1.0 4 O43505 1 +Protein mannosylation 0.5110309940410129 0.3214742511032175 0.7478510221870864 1.0 1.0 4 O43505 1 +Regulation of b cell mediated immunity 0.3697940175677981 0.3214651567195302 0.747857913036144 1.0 1.0 12 O96028,Q96FZ2,Q7KZ85 3 +Regulation of isotype switching 0.3697940175677981 0.3214651567195302 0.747857913036144 1.0 1.0 12 O96028,Q96FZ2,Q7KZ85 3 +Tolerance induction 0.5826737586759525 0.3214172312344892 0.7478942266909645 1.0 1.0 3 P01889 1 +Regulation of tolerance induction 0.5826737586759525 0.3214172312344892 0.7478942266909645 1.0 1.0 3 P01889 1 +Sertoli cell development 0.5109774436090257 0.3213292031288854 0.7479609279894348 1.0 1.0 4 Q9Y2H6,P51153,P46100 3 +B cell activation 0.3180476811889884 0.3213039514654744 0.7479800622123447 1.0 1.0 35 P14174,O96028,Q9UQ84,P78536,Q7KZ85,P02786,P17812,Q96FZ2 8 +Organ growth 0.3245376721358921 0.3195713399993929 0.7492933032824896 1.0 1.0 25 P07602,P31749,O75844 3 +Neuromuscular process controlling balance 0.3769576551956696 0.3191967873816951 0.7495772929473947 1.0 1.0 11 Q8IZL8,P17900,P07196 3 +Pathway restricted smad protein phosphorylation 0.4092272578037627 0.3191001498549422 0.7496505700305873 1.0 1.0 7 Q93062,Q9Y4E8 2 +Postsynapse organization 0.3200934503474348 0.3172867028613712 0.7510260661036041 1.0 1.0 32 Q16352,Q9UQB8,P07196,P18085 4 +Response to salt 0.4448350029444957 0.3167532951757379 0.7514308056711658 1.0 1.0 5 P07196,Q14103 2 +Eye photoreceptor cell differentiation 0.5089298778653143 0.3158057333276178 0.7521499660981654 1.0 1.0 4 Q15555 1 +Neuromuscular synaptic transmission 0.5659753531710334 0.3154601249181324 0.7524123222501886 1.0 1.0 2 Q8IUD2 1 +Secretory granule localization 0.5653742110009051 0.3139434330345328 0.7535640019979148 1.0 1.0 2 P33176 1 +Regulation of fc receptor mediated stimulatory signaling pathway 0.5787733012627676 0.3118689969424051 0.7551400850527832 1.0 1.0 3 Q9UKG1,P41240 2 +Positive regulation of cell growth 0.3084628487079002 0.3118242349218092 0.7551741049143117 1.0 1.0 42 Q6PJG6,O00571,Q9BSK2,P78536,O75832,Q7Z4V5,P31749,Q9UJX6,Q96K76,O43909,Q7L576,O95684 12 +Membrane docking 0.3198489195137325 0.3108387604705416 0.7559232016750206 1.0 1.0 31 Q7Z6M1,Q9P253,P16615,O43752,O95721 5 +Microglial cell activation 0.5056274403613134 0.3069908308067133 0.7588503514244709 1.0 1.0 4 P10909,P15260 2 +Epithelial cell proliferation 0.3020223861032099 0.3056216022019211 0.7598927708129479 1.0 1.0 52 P78536,P11047,P57105,O94788,Q92766,Q8WTV0,P31749,P09601,Q9H2J4,P28482,Q13247,O75340,P15291 13 +Intrinsic apoptotic signaling pathway in response to oxidative stress 0.3385558981824044 0.3051276749713047 0.7602689140434669 1.0 1.0 17 Q9NR28 1 +Glandular epithelial cell differentiation 0.4038101674183073 0.2994544658798968 0.76459330978712 1.0 1.0 7 P31749 1 +Glandular epithelial cell development 0.4038101674183073 0.2994544658798968 0.76459330978712 1.0 1.0 7 P31749 1 +Regulation of receptor binding 0.5735912445366131 0.2994186097951192 0.7646206645540876 1.0 1.0 3 P16615 1 +Smooth muscle cell migration 0.3719374062112042 0.2969765817727686 0.7664843880547247 1.0 1.0 11 P46108 1 +Organic cyclic compound catabolic process 0.3580908793446142 0.2953463006288429 0.7677293503288882 1.0 1.0 190 Q7Z739,Q969T7,Q9H773,Q92945,P30519,Q8WTV0,P16989,Q14103,Q9BQG2,Q9Y5A9,Q06787,O60506,P98175,P09601,Q99729,P51530,P67809,P51114,Q14011,P31749,Q9NYY8,Q13126,Q9NRW3,P51116,Q92804,O95831,Q6PGP7,P08670,P62312,Q9BRP8,P35637 31 +Phagocytosis 0.3101139462156785 0.2928572461234004 0.7696312693863285 1.0 1.0 39 Q9BZG1,P51790,Q5KU26,Q92614,Q8WTV0,P04083 6 +B cell activation involved in immune response 0.3363127999479282 0.2926346928785337 0.769801392933283 1.0 1.0 17 O96028,Q9UQ84,Q96FZ2,Q7KZ85 4 +L glutamate transmembrane transport 0.4016176771290849 0.2916040456918237 0.7705893818025253 1.0 1.0 7 Q15041 1 +Regulation of mammary gland epithelial cell proliferation 0.4995488721804546 0.291073621584898 0.7709950138115742 1.0 1.0 4 Q07812,Q92766,Q9NQC3 3 +Antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii 0.556056507363999 0.291005960532806 0.771046760854041 1.0 1.0 2 P50570 1 +Regulation of lymphocyte migration 0.3715501971762458 0.288496440609654 0.7729667547311698 1.0 1.0 10 P46108,P31749 2 +Cellular carbohydrate metabolic process 0.2948662039628758 0.287617790711632 0.7736393250635645 1.0 1.0 66 O75844,O43505,Q9NUJ1,O75874,P31749,P48735,Q14108 7 +Cytokine production 0.3117909661346664 0.286888909834106 0.7741973823922963 1.0 1.0 105 P14174,P19474,P04062,Q8IV08,Q9NUD5,P30536,P09601,P41440,Q9NUQ9,Q9Y639 10 +Regulation of golgi organization 0.4187140061234192 0.285940036524102 0.7749240486315832 1.0 1.0 6 P28482,Q9P2W9 2 +Transforming growth factor beta1 production 0.5536519386835071 0.2852629820523105 0.7754426711268019 1.0 1.0 2 O75787 1 +Regulation of transforming growth factor beta1 production 0.5536519386835071 0.2852629820523105 0.7754426711268019 1.0 1.0 2 O75787 1 +Negative regulation of tubulin deacetylation 0.5524496543432542 0.2824189545982453 0.7776222826380255 1.0 1.0 2 P54646 1 +Positive regulation of glycolytic process 0.5524496543432542 0.2824189545982453 0.7776222826380255 1.0 1.0 2 P54646 1 +P38mapk cascade 0.4959398496240636 0.2818155029092509 0.7780849829425072 1.0 1.0 4 Q99873,Q16539,P46734 3 +Regulation of wound healing 0.3444265024451842 0.281452009703339 0.7783637315875664 1.0 1.0 14 P46108,Q92766,P04083,Q13247,P55011 5 +Somatic diversification of immunoglobulins 0.3252306795448617 0.2812506242213484 0.7785181784734061 1.0 1.0 20 Q96FZ2,Q9UQ84,O96028,Q7KZ85 4 +Regulation of generation of precursor metabolites and energy 0.3075046214918997 0.2812062588662433 0.7785522044007702 1.0 1.0 40 P14406,P34897,P31749,Q9BSK2 4 +Regulation of glycoprotein metabolic process 0.3608748148406143 0.2802420605099506 0.7792917993141704 1.0 1.0 12 Q9BXS4 1 +Cellular extravasation 0.3983761682912417 0.2801072728807647 0.7793952050204882 1.0 1.0 7 P46108 1 +Negative regulation of transforming growth factor beta production 0.5503456567478303 0.2774861773593922 0.7814068181348977 1.0 1.0 2 Q9Y5K6 1 +Macrophage differentiation 0.4312833136880286 0.2760941688768423 0.7824757392418387 1.0 1.0 5 P04062 1 +Small rna loading onto risc 0.4311466811539074 0.2756955135864435 0.7827819417790074 1.0 1.0 5 O94992 1 +Positive regulation of epithelial cell apoptotic process 0.5488428013225156 0.2739973995614365 0.7840866200661327 1.0 1.0 2 P05198 1 +Endothelial cell apoptotic process 0.5488428013225155 0.2739973995614362 0.7840866200661329 1.0 1.0 2 O96013 1 +Macrophage activation 0.3692815097023884 0.2733364815371663 0.7845945744498724 1.0 1.0 9 P14174,P15260,Q92614 3 +Immune response 0.3658218320201853 0.273302568616409 0.7846206410016396 1.0 1.0 227 P62942,P14174,P28070,P25786,P34897,Q9Y487,Q9Y5A9,O60506,O95373,O43823,P10321,Q9NPR9,Q96FW1,P09601,P41440,Q96PK6,Q9NUQ9,P19474,Q8TCT8,Q9NUD5,Q9NZ08,P49327,Q9UQ84,Q9NRW3,P46379,Q7KZ85,P46108,Q03518,O43657,P04083,P28482,P08670 32 +Regulation of water loss via skin 0.4146027238926726 0.2728397479221426 0.7849764038739966 1.0 1.0 6 P04062 1 +Cellular modified amino acid biosynthetic process 0.3215633248807493 0.2714438639546269 0.786049669378116 1.0 1.0 22 P00374,Q9NVH6 2 +Oocyte differentiation 0.3674723094332141 0.2712046937113873 0.7862336031626487 1.0 1.0 10 Q15645,Q9H6S0,Q9Y5A9,P30153 4 +Natural killer cell mediated immunity 0.3659763819236863 0.2710284252378775 0.7863691700025615 1.0 1.0 11 P46108,P04439 2 +Negative regulation of protein metabolic process 0.3655597541554207 0.2709876226052538 0.7864005519428434 1.0 1.0 301 P62942,Q969T7,P14174,O95197,Q96PZ0,Q9BXS4,Q15392,Q01105,Q9NQ11,P34897,P30153,Q9Y5A9,Q9UMY4,O95684,O60506,O95373,Q32P28,P00374,Q96FW1,P30086,P67809,P51114,P04062,O60925,P19474,Q16850,Q15041,Q6DKJ4,Q14011,P34896,P31749,P07858,O75718,P30536,Q9H2J4,P10619,P46379,P51116,Q7KZ85,Q16799,Q15363,P06730 42 +Response to hydroperoxide 0.5470393748121528 0.2698491289234187 0.7872763249072194 1.0 1.0 2 P18887 1 +Positive regulation of lipid catabolic process 0.547039374812146 0.2698491289234028 0.7872763249072317 1.0 1.0 2 P50416 1 +Negative regulation of filopodium assembly 0.5470393748121445 0.2698491289233994 0.7872763249072343 1.0 1.0 2 P47756 1 +Dna replication initiation 0.321304677292324 0.2698454575649891 0.7872791494926523 1.0 1.0 22 Q14181,Q9Y619 2 +Cardiac conduction 0.3356128575789883 0.2688912984161665 0.7880133333109014 1.0 1.0 16 P16615,P0DP25,O75844 3 +Negative regulation of glucose import 0.5458370904719032 0.2671068849338363 0.7893868667161996 1.0 1.0 2 O00186 1 +Calcium mediated signaling 0.3207092307755035 0.2661704142445977 0.7901079673853517 1.0 1.0 22 P78417,O75844,P42858,P16615,P0DP25 5 +Negative regulation of oxidoreductase activity 0.4895760543125431 0.2658478637750077 0.7903563791799355 1.0 1.0 4 Q15070 1 +Regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway 0.3755378329763237 0.2658056055069782 0.790388925904915 1.0 1.0 8 O60313 1 +Negative regulation of intracellular protein transport 0.3661831273561274 0.2657863586517772 0.7904037496838541 1.0 1.0 10 O95429,P49257 2 +Retinol metabolic process 0.3940397350993337 0.2649373038630642 0.7910577604976319 1.0 1.0 7 Q9Y394,O94788,Q9BTZ2,Q9HBH5,Q8TC12,Q8NBN7 6 +Thymus development 0.375274201800182 0.2647939048693795 0.7911682325603566 1.0 1.0 8 O75844 1 +Icosanoid transport 0.4889244616338166 0.2642390249811471 0.7915957417686623 1.0 1.0 4 P14174 1 +Posttranslational protein targeting to membrane translocation 0.4887218045112818 0.2637396445633587 0.7919805448086175 1.0 1.0 4 Q9UGP8,P61619,Q99442 3 +Fat soluble vitamin metabolic process 0.4116059561482685 0.2634212573223889 0.7922259080418446 1.0 1.0 6 P38435,P04062 2 +Cohesin loading 0.5434325217914016 0.2616784663627171 0.7935693435466302 1.0 1.0 2 Q7Z5K2 1 +Negative regulation of cell activation 0.3306019281746828 0.2612072876486747 0.7939326584305821 1.0 1.0 17 P04083,P09601 2 +Positive regulation of nuclear division 0.3741406013194383 0.2604547221170086 0.7945130368261168 1.0 1.0 8 Q9UJX4,Q9UJX3 2 +Positive regulation of mitotic nuclear division 0.3741406013194383 0.2604547221170086 0.7945130368261168 1.0 1.0 8 Q9UJX4,Q9UJX3 2 +Dna dealkylation involved in dna repair 0.4872180451127847 0.2600489647923373 0.794826004024753 1.0 1.0 4 Q9C0B1,Q8N3C0,Q13686 3 +Nucleoside phosphate biosynthetic process 0.3049235375762635 0.2593988981459583 0.7953274797797041 1.0 1.0 99 P50897,P43490,O75964,P17812,P34896,Q9UMR5,Q9BQG2,Q7LG56,P00846,Q9NZ01,O95563 11 +Endocrine pancreas development 0.3912134383092381 0.2551832505138349 0.7985815670780609 1.0 1.0 7 P31749 1 +Vesicle cargo loading 0.361791794782749 0.2531120285263692 0.8001816440475582 1.0 1.0 11 Q15363 1 +B cell proliferation 0.3628913594740947 0.2520596997970227 0.8009949193028356 1.0 1.0 10 P14174,P17812,P02786 3 +Meiotic cell cycle 0.2955052255565865 0.2493787729643275 0.8030678032871934 1.0 1.0 57 Q9UQ84,O94901,P53350,P46379,Q92791,Q08J23,O43683,O15360,Q9H6S0,P30153,O60566,Q9BTX1,Q9Y5A9,Q15645,Q9Y2W6 15 +Transforming growth factor beta production 0.5505111244738301 0.2473463292112751 0.8046402068741239 1.0 1.0 3 O75787,Q9Y5K6 2 +Telomerase holoenzyme complex assembly 0.5505111244738284 0.2473463292112717 0.8046402068741265 1.0 1.0 3 P07900,Q15185 2 +Neural tube formation 0.3191529153439012 0.2452662970618454 0.8062502459156935 1.0 1.0 20 Q15363,P11233,O60313 3 +Regulation of coagulation 0.5359182446648731 0.2452001134856293 0.8063014885211304 1.0 1.0 2 Q05655 1 +Nuclear transcribed mrna catabolic process exonucleolytic 3 5 0.3609465682159317 0.2440247651081869 0.8072116398167222 1.0 1.0 10 Q13868,Q6PGP7,Q5RKV6,Q96B26 4 +Positive regulation of peptidyl serine phosphorylation 0.3169949036535266 0.2433987791129561 0.8076964895026988 1.0 1.0 22 P14174,P02786,Q13043,P35080,O95429,P31749,Q99996 7 +Intracellular transport 0.2795276468348099 0.2432511293743789 0.8078108605504082 1.0 1.0 578 Q9NS69,O43731,P00846,P24390,Q99595,O43772,Q8N4Q1,O75503,O60725,Q8NBN3,P45880,Q15629,P23786,P10619,Q8N4H5,Q9Y282,P46379,O95831,O75964,Q03518,Q15363,Q14168,P43307,Q5JRX3,O75844,Q99523,P07602,Q9UMY4,Q14108,O95373,O43752,Q15070,Q15041,P22626,P31749,P30536,P49257,O60313,Q9P260,Q9P2W9,Q7KZ85,O95391,O14925,P55786,Q96JB2,O95140,P12235,Q9NQ11,P53365,Q9P253,Q92973,Q96L92,P18085,P42858,Q4J6C6,P07196,Q8IUR0,Q9HAV4,Q9BVK6,P84085,O15027,P20645,O95429,O14737,P28482,Q9UBX3,O15118,O15397,Q8WWC4,Q86U38,Q9Y6Y8,Q92783,Q9UBK9,Q9Y5X3,Q9BXI6,Q92734,Q96PC5,Q08J23,O95613,O95071,Q9BUN8,P52789,P09651,P09132,O75340,Q9Y512,Q9Y2T2,Q86W42,Q00535,P61020,P16615,Q9Y5M8 92 +Layer formation in cerebral cortex 0.479660607857155 0.2419009699522219 0.8088568985379021 1.0 1.0 4 Q00535 1 +Cellular response to lipid 0.309877483654377 0.240142886816745 0.8102194878955773 1.0 1.0 108 P14174,O43823,O95831,Q969T9,Q8WTV0,P08670,O15118,P31749,O15173,Q02790,P30536,P04083,Q9P253,P06730,Q9UBS8,P28482,Q15120 17 +Positive regulation of dna ligation 0.53351367598438 0.2400835458979419 0.8102654896974713 1.0 1.0 2 P18887 1 +Positive regulation of toll like receptor 9 signaling pathway 0.5335136759843684 0.2400835458979176 0.8102654896974901 1.0 1.0 2 Q9NQC3 1 +Toll like receptor 9 signaling pathway 0.5335136759843684 0.2400835458979176 0.8102654896974901 1.0 1.0 2 Q9NQC3 1 +Regulation of toll like receptor 9 signaling pathway 0.5335136759843684 0.2400835458979176 0.8102654896974901 1.0 1.0 2 Q9NQC3 1 +Protein import 0.2970085565382807 0.2399895096847433 0.8103383890556284 1.0 1.0 91 O95373,Q99595,O95831,O95071,Q9NS69,P31749,Q8N4Q1,O14925,O14737,O15397,Q92973 11 +Granulocyte migration 0.3266439312457797 0.2397647907644458 0.8105126037649102 1.0 1.0 17 P04083,Q8N5M9,P35613 3 +Germ cell proliferation 0.5332131048993154 0.2394493398847686 0.8107571748125324 1.0 1.0 2 Q13162 1 +Positive regulation of g protein coupled receptor signaling pathway 0.5460012026458069 0.2378370837663881 0.8120074551145315 1.0 1.0 3 P35232,O14744 2 +Negative regulation of cellular respiration 0.4769924812030105 0.2356555207535894 0.8136999871484281 1.0 1.0 4 Q6L8Q7,P61586,P30405 3 +Regulation of systemic arterial blood pressure by renin angiotensin 0.5308085362188238 0.2344187159367377 0.8146599301756656 1.0 1.0 2 O75787 1 +Cleavage furrow formation 0.5308085362188182 0.234418715936726 0.8146599301756747 1.0 1.0 2 Q9Y5X1 1 +Regulation of vascular associated smooth muscle contraction 0.5308085362188144 0.2344187159367177 0.8146599301756812 1.0 1.0 2 P20020 1 +Positive regulation of protein containing complex disassembly 0.3596709962218074 0.234393354666171 0.8146796171808379 1.0 1.0 9 P04062 1 +Negative regulation of protein localization 0.294167717187685 0.2342977696177892 0.8147538173281785 1.0 1.0 50 Q8N183,Q16850,Q16836,Q9BXS4,O95429,Q00535,Q8N5M9,P49257,Q9UMY4 9 +Negative regulation of mapk cascade 0.3094708693528876 0.2335008656845406 0.8153724974128458 1.0 1.0 30 P30086,P30153 2 +Endocytosis 0.3233280437453559 0.2326509326044906 0.8160324737941926 1.0 1.0 129 P50897,P62993,Q5KU26,Q92614,Q99523,Q9NX40,Q96D71,Q8WTV0,Q5SW96,O15118,Q9UBG0,P11717,Q9UMY4,Q06787,Q14108,P51790,P61978,Q9Y5X3,P41440,Q08380,P0DP25,P57105,P51148,Q7Z6M1,Q9UBF8,Q5VW38,P02786,P28482,Q9Y2T2,P20645,Q00535,P61020,P10909 33 +Synapse assembly 0.3282273288693353 0.2301033494530859 0.8180114622370032 1.0 1.0 16 Q00535,Q9Y639 2 +Rna catabolic process 0.3319306882272667 0.2296108402570865 0.8183941826109018 1.0 1.0 144 Q7Z739,Q969T7,Q92945,P16989,Q14103,Q9BQG2,Q9Y5A9,O60506,P98175,Q99729,P67809,P51530,P51114,Q14011,P31749,Q9NYY8,P51116,Q92804,Q6PGP7,P08670,P62312,Q9BRP8,P35637 23 +Positive regulation of non motile cilium assembly 0.4129731950068218 0.2247989752070004 0.822135663342541 1.0 1.0 5 Q15555 1 +Positive regulation of ubiquitin protein ligase activity 0.5393841580383173 0.2242901600401576 0.8225315323337807 1.0 1.0 3 Q16763 1 +Regulation of mrna export from nucleus 0.4126067644320815 0.2238175892681663 0.8228992428863875 1.0 1.0 5 Q7KZ85,Q08J23 2 +Regulation of nuclear transcribed mrna catabolic process nonsense mediated decay 0.4118911136770695 0.2219061778932429 0.8243869211644257 1.0 1.0 5 Q99729 1 +Striated muscle contraction 0.314256724118726 0.2211895775591189 0.8249448241950743 1.0 1.0 21 P78417,P09493,P16615,P30626,Q99996,P10253,P0DP25,P05023 8 +Interleukin 6 production 0.3400911307158776 0.2201127910793464 0.8257833132530912 1.0 1.0 13 P01889,Q9NRA0,P04062 3 +Ribonucleoprotein complex localization 0.3969986926086156 0.2191627510093896 0.8265232704917516 1.0 1.0 6 Q7KZ85,Q08J23 2 +Regulation of complement activation 0.5358790654723508 0.2173114514356133 0.8279656333750274 1.0 1.0 3 Q07021 1 +Regulation of humoral immune response 0.5358790654723508 0.2173114514356133 0.8279656333750274 1.0 1.0 3 Q07021 1 +Regulation of myelination 0.353160009753143 0.2169870207921945 0.828218459886326 1.0 1.0 11 P31749,Q7L576,Q15058 3 +Regulation of neurogenesis 0.2921190605602009 0.2168296734943881 0.8283410859363904 1.0 1.0 57 Q96G23,Q9UQB8,P30536,Q9UJX6,Q9Y5A9,Q9Y639 6 +Ribonucleoside triphosphate metabolic process 0.2994578781630415 0.2155828127055738 0.8293129542528597 1.0 1.0 40 P00846,O75964,P17812 3 +Cop9 signalosome assembly 0.5211902614968407 0.2150648826790961 0.8297167328117458 1.0 1.0 2 Q99627 1 +Dendrite arborization 0.520889690411789 0.2144799743041056 0.8301727818057594 1.0 1.0 2 Q13641 1 +Histone phosphorylation 0.312069729629823 0.2136311402563556 0.830834713538062 1.0 1.0 22 O43823,O75844,O14757,Q00535,Q9ULX6,Q06787 6 +Sertoli cell differentiation 0.4085439229843583 0.2130593549421311 0.8312806667913013 1.0 1.0 5 Q9Y2H6,P51153,P51659,P46100 4 +Positive regulation of activated t cell proliferation 0.5336740829825438 0.2129917806653669 0.8313333736762023 1.0 1.0 3 P23396,Q9HCL2 2 +Positive regulation of blood circulation 0.4083009576346718 0.2124231913391596 0.8317768945311383 1.0 1.0 5 P09493 1 +Long chain fatty acid biosynthetic process 0.5327720986169511 0.2112404946684969 0.8326996134434257 1.0 1.0 3 O00154,Q96PU8 2 +Mononuclear cell migration 0.3079719534716813 0.2111983625674029 0.832732488419746 1.0 1.0 25 P46108,P31749,P04083,P28482,P04062 5 +Negative regulation of striated muscle cell apoptotic process 0.5190862639014255 0.2109959270774906 0.832890449537236 1.0 1.0 2 O95817 1 +Segmentation 0.32988753102047 0.2097038522154573 0.8338988187542142 1.0 1.0 14 Q15363,O14641,Q9Y2W6 3 +Positive regulation of leukocyte cell cell adhesion 0.3114039124311193 0.209646236457357 0.8339437899838344 1.0 1.0 22 P31749,P04083,Q9NUQ9 3 +Glomerular visceral epithelial cell migration 0.5178839795611748 0.2086974374925885 0.8346844406807232 1.0 1.0 2 Q9NQW6 1 +Positive regulation of peptidyl tyrosine phosphorylation 0.3239580938456386 0.2081455209471572 0.8351153448532029 1.0 1.0 16 P14174,O14641 2 +Negative regulation of oxidative phosphorylation 0.5309681298857492 0.2077654183736134 0.835412135515516 1.0 1.0 3 Q6L8Q7,P30405 2 +Negative regulation of cell cycle g2 m phase transition 0.3087372524420266 0.2072505971342811 0.8358141542064752 1.0 1.0 24 O14757,Q9Y619 2 +Myeloid leukocyte activation 0.3086407010046472 0.2066495765933851 0.8362835393230323 1.0 1.0 24 P14174,Q9NRA0,Q92614,P15260,P04083,P09601 6 +Nik nf kappab signaling 0.3124579826497951 0.2064705436152794 0.8364233718039054 1.0 1.0 20 O00571,Q9H000,O43657,P31749,O15111 5 +Leucine transport 0.51668169522092 0.206418328255295 0.8364641552268659 1.0 1.0 2 Q9H2J7 1 +Branched chain amino acid transport 0.51668169522092 0.206418328255295 0.8364641552268659 1.0 1.0 2 Q9H2J7 1 +Regulation of cell cell adhesion 0.2899214269143654 0.2060875321443881 0.8367225376412575 1.0 1.0 46 Q9Y5A9,Q9NUQ9,P41440 3 +Mammary gland involution 0.5163811241358596 0.2058515802795066 0.8369068486762317 1.0 1.0 2 Q07812 1 +Regulation of dendrite development 0.311614685146467 0.2056832971025126 0.8370383065783749 1.0 1.0 21 Q9UQB8,P46108,Q9UJX6,O60828,Q7L576 5 +Ossification 0.288232824896067 0.2053579154019125 0.8372924981597025 1.0 1.0 64 Q15125,O75844,P49327,P28482,Q99523,P38159,P31749,Q9UBG0,Q9H6W3,O60506 10 +Golgi to plasma membrane protein transport 0.320156015384613 0.2052631043841154 0.837366568713469 1.0 1.0 17 Q9H4A6,Q9BZG1,O15027,Q4J6C6,Q9H4A5 5 +Regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator 0.3913047853515975 0.2026879952457165 0.8393789068281241 1.0 1.0 6 P14174,P61978 2 +Fatty acid derivative metabolic process 0.3088850814860466 0.2007462100999528 0.8408970247070906 1.0 1.0 23 P50897,Q9UJ14,Q9UMR5 3 +Skin development 0.2963348964804997 0.199615075600946 0.8417816364505311 1.0 1.0 41 Q16739,O75844,Q08J23,Q15392,P04083,Q8NEY8,Q13510,P04062 8 +Erythrocyte maturation 0.5127742711151276 0.1991451710387538 0.8421491874329319 1.0 1.0 2 P18074 1 +Negative regulation of cellular response to insulin stimulus 0.3574224631135159 0.1986613867483932 0.8425276308265222 1.0 1.0 8 Q05655,P49840,P78356,Q13131,Q9HCD5,P18031,P49815 7 +Roundabout signaling pathway 0.5124737000300682 0.198594186666317 0.8425802014049224 1.0 1.0 2 P61586 1 +Negative chemotaxis 0.5124737000300682 0.198594186666317 0.8425802014049224 1.0 1.0 2 P61586 1 +Embryonic hemopoiesis 0.4601955394321875 0.1983293213567922 0.8427874121860448 1.0 1.0 4 Q03164 1 +Positive regulation of cell adhesion 0.2893257710793693 0.1978720651995101 0.8431451607662412 1.0 1.0 60 Q99797,P02786,P46108,P04439,Q9Y2S7,Q13043,Q92766,P09493,O95429,P31749,P04083,Q9HCL2,P41440,Q53GQ0,P36404,Q9NUQ9 16 +Regulation of dendrite morphogenesis 0.3273552814244703 0.1976000007290146 0.8433580342331495 1.0 1.0 14 Q9UQB8 1 +Positive regulation of cartilage development 0.5115719867748827 0.1969485118922138 0.8438678300702018 1.0 1.0 2 P20248 1 +Positive regulation of alcohol biosynthetic process 0.511571986774881 0.196948511892211 0.843867830070204 1.0 1.0 2 Q13131 1 +Positive regulation of cholesterol biosynthetic process 0.511571986774881 0.196948511892211 0.843867830070204 1.0 1.0 2 Q13131 1 +Regulation of map kinase activity 0.3110350745139315 0.1955050054033174 0.8449976195438209 1.0 1.0 19 P14174,P04062 2 +Negative regulation of intracellular transport 0.3147827421306077 0.195338429490467 0.8451280141077506 1.0 1.0 18 O95429,Q9UMY4,P49257 3 +Medium chain fatty acyl coa metabolic process 0.5106702735196946 0.1953137549935166 0.8451473295077327 1.0 1.0 2 O00154 1 +Long chain fatty acyl coa metabolic process 0.3492759876192001 0.1938664634463687 0.8462804437620972 1.0 1.0 9 Q9NZ01 1 +Negative regulation of cell differentiation 0.2804312418590309 0.1930870539634655 0.846890791315547 1.0 1.0 76 Q96G23,Q8N4Q0,Q99523,P04083,P30536,P06730,Q9H6W3,Q9Y5A9,P67809 9 +Regulation of striated muscle cell differentiation 0.34805505040987 0.1922544578562118 0.8475428902359265 1.0 1.0 10 P67809 1 +Golgi vesicle transport 0.3251491012984104 0.1906878581036829 0.8487701519693558 1.0 1.0 138 Q92614,Q99523,O43731,Q9UMY4,Q9Y6Y8,P24390,P18085,P42858,Q4J6C6,Q92734,Q8IUR0,O43752,Q9BVK6,Q96PC5,P49257,P84085,Q9Y282,O15027,Q9P2W9,Q15363,Q96JB2 21 +Cognition 0.2952286133101368 0.1906255089880412 0.8488190033748624 1.0 1.0 41 P50897,P17900,P18085,P42858,Q00535,P28482,Q7L576,P42574,Q9Y639,O00264 10 +Mammary gland epithelial cell proliferation 0.3868380534724939 0.1900832802857061 0.8492438716203472 1.0 1.0 6 P28482 1 +Negative regulation of adaptive immune response 0.5067628494138986 0.1883559574042322 0.8505976225932419 1.0 1.0 2 P14373 1 +Positive regulation of wound healing 0.3858552492094798 0.1873482986383624 0.8513875564852329 1.0 1.0 6 P04083 1 +Positive regulation of transmembrane transport 0.2986552983468356 0.1868763702221291 0.851757566635758 1.0 1.0 37 P08183,P78417,Q15041,P42858,Q9Y4C2,P31749,Q99996,Q00535,P0DP25 9 +Positive regulation of pathway restricted smad protein phosphorylation 0.45457538010531 0.1866244609450746 0.8519550866262591 1.0 1.0 4 Q93062 1 +Relaxation of muscle 0.4544360902255678 0.1863394460609771 0.8521785756469464 1.0 1.0 4 P28161,P05023,P30626 3 +Intracellular sterol transport 0.3464887498337207 0.1861501999074979 0.8523269759905183 1.0 1.0 10 Q5SW96,Q9P260,O15118 3 +Leukocyte adhesion to vascular endothelial cell 0.4541353383458684 0.1857248886283496 0.852660509579628 1.0 1.0 4 Q9H4A6,P61586,Q13464 3 +Bergmann glial cell differentiation 0.3969754115733686 0.1836899377712596 0.8542567030858954 1.0 1.0 5 P28482 1 +Nadh oxidation 0.5034565674782214 0.18262861201103 0.8550894327568352 1.0 1.0 2 P43304 1 +Nuclear transcribed mrna catabolic process 0.2868614380904867 0.1814260415358763 0.8560331798521132 1.0 1.0 62 Q969T7,Q6PGP7,Q99729,P67809,Q9BRP8,O60506 6 +Histamine production involved in inflammatory response 0.4517293233082738 0.1808498790554 0.8564854107379221 1.0 1.0 4 Q9UNH7,O95219,O00161 3 +Histamine transport 0.4517293233082738 0.1808498790554 0.8564854107379221 1.0 1.0 4 Q9UNH7,O95219,O00161 3 +Histamine secretion 0.4517293233082738 0.1808498790554 0.8564854107379221 1.0 1.0 4 Q9UNH7,O95219,O00161 3 +Establishment of protein localization to membrane 0.2948388626689243 0.180053146747967 0.8571108448541849 1.0 1.0 95 P46379,Q15070,Q15041,O15027,Q15629,Q9HD20,P09132,Q9NS69,Q4J6C6,O14737,O15118,Q8WWC4,O60725,P43307,Q9Y512 15 +Regulation of vesicle fusion 0.4508878941851352 0.1791624219812785 0.857810169175194 1.0 1.0 4 O60343 1 +Positive regulation of myeloid cell apoptotic process 0.5145172366834888 0.1777799625962206 0.8588957841930192 1.0 1.0 3 P04083 1 +Pyrimidine nucleobase biosynthetic process 0.3510998915658665 0.1764388990216685 0.8599491469907004 1.0 1.0 8 P17812 1 +Regulation of ubiquitin specific protease activity 0.4491574005272454 0.1757204367833282 0.8605135788969691 1.0 1.0 4 Q9NQ11 1 +Activation of protein kinase c activity 0.4992485722873466 0.1755510733020777 0.860646643116981 1.0 1.0 2 P35232 1 +Positive regulation of phospholipid biosynthetic process 0.4478195488721844 0.1730857254367209 0.8625840450563198 1.0 1.0 4 P17655,O95573,Q9UHD1 3 +Positive regulation of cholesterol metabolic process 0.5117257967528385 0.1729987993507144 0.8626523713732537 1.0 1.0 3 Q5SW96,Q13131 2 +Hippocampus development 0.3068452959481107 0.1723835284953528 0.8631360206934597 1.0 1.0 19 P46108,P07196,Q00535,O14949 4 +Pyrimidine ribonucleoside triphosphate metabolic process 0.3427203771417838 0.1716378861359783 0.8637222205932815 1.0 1.0 10 P17812 1 +Negative regulation of interleukin 2 production 0.4956417192666187 0.1696729465404959 0.8652673510738706 1.0 1.0 2 P14373 1 +Regulation of p38mapk cascade 0.4956417192666007 0.1696729465404668 0.8652673510738935 1.0 1.0 2 Q99873 1 +Regulation of steroid biosynthetic process 0.3286410427945461 0.1688009601671318 0.8659532030596679 1.0 1.0 13 Q9UBM7,P30536 2 +Regulation of cell shape 0.2995205191379759 0.1686204494838397 0.8660951945258251 1.0 1.0 32 P46108,Q9UQB8,P09493,O75844 4 +Retinal metabolic process 0.4454135338345903 0.1684052794840604 0.8662644549948164 1.0 1.0 4 O94788,Q9BTZ2,Q8TC12 3 +Positive regulation of golgi to plasma membrane protein transport 0.4947400060114215 0.1682305077695977 0.8664019412325674 1.0 1.0 2 P63244 1 +Very low density lipoprotein particle assembly 0.4947400060114162 0.1682305077695893 0.8664019412325741 1.0 1.0 2 P35610 1 +Tissue morphogenesis 0.2763338308912645 0.1666859557800223 0.8676171565960265 1.0 1.0 74 P62942,P62993,P78536,O14641,Q13043,Q92766,P11233,P09493,Q15363,Q9BRK4,P67870,O00471,P35453,P42574,O60313 15 +Organelle transport along microtubule 0.2994664364218737 0.1660397789767881 0.8681256455457718 1.0 1.0 31 O94901,Q8TD16,Q8WXH0,P42858,Q9UBK9,Q9Y2T2,Q5SNT2,Q9UH62,P07196,O60313 10 +Regulation of adaptive immune response 0.3020031116397195 0.1658472358277146 0.8682771720116063 1.0 1.0 24 O96028,Q7KZ85,P02786,P04083,P04439,Q96FZ2,Q9NUQ9 7 +Protein localization to cell junction 0.3038188200370186 0.1649560794625613 0.8689785519023085 1.0 1.0 22 Q9UQB8 1 +Positive regulation of cell substrate junction organization 0.3409634218393489 0.1627553171737753 0.8707110907959859 1.0 1.0 9 Q15555 1 +Regulation of endocytic recycling 0.4424060150375969 0.1626596093488929 0.8707864504355578 1.0 1.0 4 P35609,Q15907,Q07960 3 +Negative regulation of axonogenesis 0.3879292862439737 0.1620674930575141 0.8712527045173737 1.0 1.0 5 Q00535 1 +Centriole assembly 0.3407583443592502 0.1620031232905111 0.8713033943318771 1.0 1.0 9 Q9C0F1,Q96PK6 2 +Cytosolic transport 0.279751746113525 0.161785315767737 0.8714749170158633 1.0 1.0 70 Q9BVK6,Q99523,Q4J6C6,Q9Y5X3,O75503,P49257,P28482,O43752,Q9UMY4,Q8NBN3 10 +Negative regulation of cytoskeleton organization 0.2854466029435026 0.160585546682649 0.8724198392247651 1.0 1.0 48 Q02790,Q96PK6,Q9NUQ9,Q9UJX6 4 +Regulation of dna primase activity 0.5040440199817039 0.160303189326879 0.872642246646792 1.0 1.0 3 P49643 1 +Positive regulation of interleukin 2 production 0.375816783927741 0.160225893686433 0.8727031326820085 1.0 1.0 6 P04083,Q92990 2 +Nucleobase biosynthetic process 0.3080879242250328 0.1597862972058834 0.873049418632653 1.0 1.0 18 P34897,P17812,Q06203,P34896 4 +Pyrimidine deoxyribonucleotide biosynthetic process 0.3868527317793698 0.1595746264013334 0.8732161680148267 1.0 1.0 5 P34896 1 +Small molecule biosynthetic process 0.325756885243423 0.1578340072458383 0.874587600606207 1.0 1.0 144 P14174,Q9UJ14,P37268,Q9UBX3,Q9P035,Q15392,P34897,Q14739,Q9BY49,A1L0T0,P00374,Q9H4L5,Q15800,Q13510,P04062,Q16850,Q8NI60,P48449,P34896,Q13126,P35270,Q9NZ01,P49327,Q9BYT8,O15270,Q15125,Q9UBM7,P04083,Q01469 29 +Positive regulation of leukocyte proliferation 0.3187482226776199 0.1574201721949312 0.8749137165445924 1.0 1.0 14 P14174,P02786,P04083,P04439,P28482 5 +Protein insertion into mitochondrial membrane involved in apoptotic signaling pathway 0.4872257288848809 0.1566296253219365 0.8755367530808895 1.0 1.0 2 Q07812 1 +Cellular amino acid biosynthetic process 0.2977740319466934 0.1564297728544369 0.875694270697613 1.0 1.0 32 P00374,Q13126,P34896 3 +Cellular response to hydrogen peroxide 0.3034354224747341 0.1557433793263978 0.8762353025953833 1.0 1.0 20 O95831,Q99720 2 +Amino acid import 0.344807280709816 0.1549940489876717 0.8768260088317417 1.0 1.0 8 Q15041 1 +Proton transmembrane transport 0.2855758665910611 0.1548321766530209 0.8769536237880984 1.0 1.0 45 Q13423,Q7KZN9,P51790,Q9BSH4,Q9NRA0,P20674,P47985,O14548,P12235,O75964,Q9UDW1,P56134,P24539,P31930,P00846,P21281,P05023,P05141 18 +L aspartate transmembrane transport 0.4372932330827105 0.1531604512104019 0.8782717449936015 1.0 1.0 4 Q9UJS0,Q15758,O75746 3 +Phagolysosome assembly 0.4354887218045151 0.1498887620548025 0.8808523781319102 1.0 1.0 4 Q9BZG1,P61106,Q9NVJ2 3 +Phagosome maturation 0.435488721804515 0.1498887620548022 0.8808523781319104 1.0 1.0 4 Q9BZG1,P61106,Q9NVJ2 3 +Positive regulation of monocyte chemotaxis 0.4821160204388435 0.1491659643034781 0.8814226760328638 1.0 1.0 2 P09429 1 +Trophoblast cell migration 0.496833531498973 0.1490027046288283 0.8815514988057371 1.0 1.0 3 Q7Z739 1 +Insulin metabolic process 0.4809137360985955 0.1474593930979699 0.8827694289085974 1.0 1.0 2 P14735 1 +Regulation of phosphatidylcholine biosynthetic process 0.494888755261553 0.1460568048035604 0.8838765454320925 1.0 1.0 3 P17655,Q8NF37 2 +Positive regulation of tumor necrosis factor mediated signaling pathway 0.3797367989143776 0.1435336927116682 0.8858687037887611 1.0 1.0 5 Q13546,P78536 2 +Enzyme linked receptor protein signaling pathway 0.3127604844078895 0.1407969742035241 0.8880303334899149 1.0 1.0 125 P62942,P62993,P43490,Q99523,Q9UIQ6,Q9Y4E8,Q8N0X7,P42574,Q9Y5X3,Q96PK6,Q9UQB8,P31749,O75340,O95470,Q9Y639,Q93062,P78536,P46108,Q6Y7W6,P28482,P08670 21 +Protein exit from endoplasmic reticulum 0.2995349141632619 0.1403263809217196 0.8884021215816513 1.0 1.0 22 P49257,O15027,Q9BVK6 3 +Vacuole organization 0.2826108420992511 0.1395644816995313 0.88900410539352 1.0 1.0 62 P50897,Q9NQ11,P53365,Q9P253,O75503,Q9HC07,O95140,Q14108,P04062 9 +Cdp diacylglycerol metabolic process 0.3776864083531038 0.1390535823435826 0.8894078077032337 1.0 1.0 5 Q9HCL2,O95674 2 +Substantia nigra development 0.3097494409874679 0.1377945689551118 0.8904027767604628 1.0 1.0 16 Q16352,P0DP25,O15027,P00367 4 +Cell cell adhesion via plasma membrane adhesion molecules 0.3121044243593575 0.137173612488185 0.8908935679060515 1.0 1.0 15 Q9Y639 1 +Atp synthesis coupled electron transport 0.2885562045996597 0.1370568039903298 0.8909858956037582 1.0 1.0 41 O43676,P20674,Q9Y6M9,Q9UDW1,O75306,O75438,O95168,Q9H3K2,O14949 9 +Skeletal muscle tissue regeneration 0.4281185455359201 0.1369659594422613 0.8910577019148529 1.0 1.0 4 P04083 1 +Regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay 0.3273295929774502 0.1365065180099082 0.8914208721578845 1.0 1.0 12 P67809,O60506 2 +Positive regulation of receptor catabolic process 0.4718966035467327 0.1352554424252741 0.8924099130631191 1.0 1.0 2 Q96J02 1 +Regulation of macroautophagy 0.2801102463540706 0.1349379959153075 0.8926608978715351 1.0 1.0 66 P21796,Q93050,P42858,P12235,Q9Y2S7,Q9NQ11,O15118,P31749,Q9Y487,P09601,O15270,P04062 12 +Purine containing compound biosynthetic process 0.2767736991085888 0.1333795823668175 0.8938931920346165 1.0 1.0 78 P50897,O75964,P34896,Q9UMR5,Q13126,Q9NZ01,P00846,Q15120,O95563 9 +Positive regulation of chromosome separation 0.3523156914725796 0.1328370103364465 0.8943222837039391 1.0 1.0 7 Q9UJX3 1 +Negative regulation of protein modification process 0.3188469404849411 0.1318860264603418 0.8950744413459275 1.0 1.0 136 P62942,P19474,O95373,Q32P28,Q7KZ85,Q6DKJ4,Q96FW1,Q9BXS4,Q01105,P31749,Q15363,P30153,P30536,O75718,O95684,P04062 16 +Myelin maintenance 0.4846925622902672 0.1313178422779319 0.8955238779154464 1.0 1.0 3 P31749 1 +Negative regulation of response to endoplasmic reticulum stress 0.3194573337589357 0.1295122637982065 0.896952321570706 1.0 1.0 13 Q04323,O60313,O95881,P10909 4 +Synapse organization 0.2795359047055618 0.1291113189428335 0.8972695657538403 1.0 1.0 66 P18085,P11047,Q9UQB8,P10586,P07196,Q9UJX6,Q00535,O15228,Q16352,Q9Y639,O00264 11 +Centromere complex assembly 0.3509933774834429 0.1291033000869533 0.8972759107725636 1.0 1.0 7 P49321,Q92674,Q9NRZ9,Q02224,Q7Z7K6,Q7Z3K3 6 +Kinetochore organization 0.3509933774834391 0.1291033000869429 0.8972759107725718 1.0 1.0 7 Q9NTJ3,O95347,O14777,Q02224,Q7Z3K3,Q9BZD4 6 +3 phosphoadenosine 5 phosphosulfate biosynthetic process 0.4667868951006942 0.1288000462940635 0.8975158688982452 1.0 1.0 2 O43252 1 +Regulation of monocyte chemotaxis 0.4822609741431003 0.1279771104908343 0.8981670872530001 1.0 1.0 3 P09429,O94813 2 +Protein import into peroxisome membrane 0.4816596512326974 0.1271612479024305 0.8988127760288422 1.0 1.0 3 P40855,P50542 2 +Negative regulation of lipid localization 0.3717424831837873 0.1264286989127365 0.8993925859696044 1.0 1.0 5 P31749 1 +Positive regulation of cell development 0.2823620799110274 0.1246329032724336 0.9008141784402846 1.0 1.0 57 Q9UQB8,P46108,P30536,Q9UJX6,Q9Y639 5 +Regulation of t cell migration 0.3608045357230525 0.122531149701052 0.9024783779581051 1.0 1.0 6 P46108 1 +Regulation of electron transfer activity 0.4192111399656613 0.1222918444643006 0.9026678906951072 1.0 1.0 4 Q9NRA0 1 +Regulation of actin filament length 0.2806573505832674 0.1222094877590403 0.9027331126348616 1.0 1.0 47 Q9UHB6,P62993,Q9UQB8,Q6ZU35,P35080,O95429,Q96F07,O15020,Q7L576,Q9NUQ9 10 +Regulation of response to wounding 0.2973200482185709 0.1213876308988496 0.9033840135450776 1.0 1.0 19 Q96G23,P46108,P10586,Q92766,P04083,Q13247,P55011 7 +Sphingomyelin catabolic process 0.4601743312293436 0.1209298697044359 0.9037465831813548 1.0 1.0 2 Q05655 1 +Activation of immune response 0.2814598834621182 0.1205851260938662 0.9040196505233687 1.0 1.0 50 P46379,Q13177,P28482,O94992,Q9NUD5,Q07666,P04439,P10909,Q96PK6,O60828,P49770 11 +Negative regulation of cell aging 0.3599707049833753 0.1205413943999025 0.9040542906936344 1.0 1.0 6 P14174 1 +Regulation of neuron differentiation 0.2959152406896863 0.1198847498473782 0.9045744451996692 1.0 1.0 22 P06730 1 +Retina morphogenesis in camera type eye 0.4175353935440252 0.1196465705407178 0.9047631267202992 1.0 1.0 4 Q15555 1 +Negative regulation of lipid transport 0.4169761774030819 0.1187719267539214 0.9054560504230702 1.0 1.0 4 P31749 1 +Extracellular exosome assembly 0.4163371354512124 0.1177773996243182 0.90624403737898 1.0 1.0 4 Q92783 1 +Regulation of cartilage development 0.3673285198556009 0.1174047872889617 0.906539290602456 1.0 1.0 5 P16435,Q06124,Q92896,P20248 4 +Regulation of dna binding 0.2913409935120608 0.1158359898182177 0.9077825267449612 1.0 1.0 26 P09601 1 +Astrocyte differentiation 0.3159744387037685 0.1150813105380986 0.9083806735028936 1.0 1.0 13 P28482,P08670,P11047 3 +Positive regulation of heart rate 0.4720704256071545 0.114698166818502 0.9086843670065232 1.0 1.0 3 P09493 1 +Establishment or maintenance of transmembrane electrochemical gradient 0.4541629095281053 0.1142389496363409 0.9090483766553954 1.0 1.0 2 Q07812 1 +Mitochondrial fragmentation involved in apoptotic process 0.3455749548464697 0.1141193951938454 0.909143147523013 1.0 1.0 7 O00429,Q8N163,Q07812,Q9Y3D6,Q96QK1,Q9NT62 6 +Regulation of protein stability 0.3043567267634179 0.1139585378059785 0.909270661296504 1.0 1.0 116 Q86Y82,Q13043,P42574,P78371,Q9UL15,Q32P28,P53350,P42858,Q9UBV2,O15164,Q96K76,P41440,P19474,P48449,Q9BUN8,Q07666,Q969V3,O75718,Q9H2J4,P10619,Q13148,O95817,P46379,O15027,P48643,P28482,P54725,P35080,O95429,Q96JB2,P10909 31 +Spontaneous synaptic transmission 0.4538623384430464 0.1139158018566723 0.909304539040453 1.0 1.0 2 P55011 1 +Regulation of spontaneous synaptic transmission 0.4538623384430464 0.1139158018566723 0.909304539040453 1.0 1.0 2 P55011 1 +Negative regulation of actin filament polymerization 0.2951449243587702 0.1127043154790857 0.9102649797948172 1.0 1.0 21 Q9NUQ9 1 +Ovulation cycle 0.3266426415475369 0.1126480205125018 0.9103096124520252 1.0 1.0 10 O95470,P04083 2 +Lens development in camera type eye 0.3564286976358394 0.1122135601310618 0.9106540776477156 1.0 1.0 6 P08670 1 +Synaptic transmission gabaergic 0.4126315789473724 0.1121148394816277 0.9107323514042932 1.0 1.0 4 P51790,P33176,Q13641 3 +Dna methylation or demethylation 0.2919177047898117 0.1119820558607987 0.9108376344199812 1.0 1.0 25 Q9NRW3,O75844 2 +Positive regulation of regulated secretory pathway 0.3447841551453266 0.1119754362075101 0.910842883128358 1.0 1.0 7 Q00535 1 +Spermidine metabolic process 0.4696494179579075 0.1117131526907359 0.9110508502743372 1.0 1.0 3 Q96QD8 1 +Cellular response to osmotic stress 0.3209480630726583 0.1115425801685585 0.9111861021535748 1.0 1.0 12 O00571,P16989,P30536,P42574 4 +Eosinophil mediated immunity 0.4514577697625435 0.1113692156114669 0.9113235705547804 1.0 1.0 2 Q12846 1 +Eosinophil activation 0.4514577697625435 0.1113692156114669 0.9113235705547804 1.0 1.0 2 Q12846 1 +Metal ion export 0.3443440393483744 0.1107870007210271 0.911785253812909 1.0 1.0 7 P0DP25,O95202 2 +Regulation of fertilization 0.4505560565073629 0.1104318404839659 0.9120669024932412 1.0 1.0 2 Q9NVM9 1 +Hydrogen sulfide metabolic process 0.4493537721671269 0.1091968331929883 0.9130463720367186 1.0 1.0 2 P25325 1 +Hydrogen sulfide biosynthetic process 0.4493537721671269 0.1091968331929883 0.9130463720367186 1.0 1.0 2 P25325 1 +Deoxyribonucleoside monophosphate biosynthetic process 0.3549922701945239 0.1088939810529764 0.913286580680032 1.0 1.0 6 P34896 1 +Regulation of nucleobase containing compound transport 0.3252201806118304 0.1088165292517476 0.913348013224632 1.0 1.0 11 Q13546,Q9ULX6,Q7KZ85,Q08J23 4 +Negative regulation of mrna 3 end processing 0.3544989467348836 0.107761628842209 0.9141847813337988 1.0 1.0 6 Q5VTR2,O75150,Q6PD62,O00267,Q6PJT7 5 +Negative regulation of protein import into nucleus 0.4475503456567458 0.1073758978863313 0.9144907746449552 1.0 1.0 2 Q9UHD1 1 +Negative regulation of protein autophosphorylation 0.4475503456567458 0.1073758978863313 0.9144907746449552 1.0 1.0 2 Q9UHD1 1 +Response to mechanical stimulus 0.2929888200006501 0.1073066592898479 0.9145457016999372 1.0 1.0 23 P42858,P49327,O14757,Q8N2K0 4 +Cytokine production involved in inflammatory response 0.3535419166497084 0.1055761831312849 0.9159186222274208 1.0 1.0 6 Q8IV08 1 +Protein processing involved in protein targeting to mitochondrion 0.4644311191780383 0.1054978534669864 0.9159807731710928 1.0 1.0 3 Q99797 1 +Transferrin transport 0.360940300987396 0.1048788926694005 0.9164719077950794 1.0 1.0 5 P50570,P02786 2 +Macromolecule catabolic process 0.2800412541655721 0.1033290409742943 0.917701827610049 1.0 1.0 450 P50897,Q969T7,P28070,Q16740,P25786,O75844,Q9UIQ6,Q9NQ11,P28074,O94888,P16989,Q9UJX6,Q9BQG2,Q9Y5A9,Q9UMY4,O60506,Q8IWV7,P20618,P60900,P98175,Q9NUJ1,O60502,O75503,Q99729,P49721,P28072,P51530,P67809,P04062,P51114,Q16850,Q14011,P31749,Q9NYY8,Q9H2J4,P10619,Q8N2K0,P46379,P51116,Q92804,O95831,P54725,Q9UHG3,Q6PGP7,Q9UJX3,P62312,P35637 47 +Intermediate filament organization 0.3521950574790645 0.1025258021151292 0.9183393336311844 1.0 1.0 6 P07196 1 +Regulation of hydrolase activity 0.3400614568788049 0.1024482309890932 0.9184009022387752 1.0 1.0 184 P62942,P50897,Q13576,Q99523,Q9Y2S7,Q15392,Q9NQ11,P07602,Q9UJX6,Q14108,P18085,P42858,Q0IIM8,P30086,Q9BXI6,Q96K76,Q9BXK5,Q15041,P31749,P07858,P49327,O75340,O60343,Q9NR28,O14641,Q15555,O95831,P46108,P04080,Q66K14,O95429,O14737,Q15363,P04083,Q96A26 35 +Pyrimidine nucleoside triphosphate biosynthetic process 0.3235090763179575 0.1017357156409236 0.9189664522303704 1.0 1.0 10 P17812,Q9NRF8 2 +Toxin transport 0.3182788946041666 0.1013559969836805 0.9192678658472008 1.0 1.0 12 P48643,Q93050 2 +Cellular glucose homeostasis 0.2898372511774805 0.1007666020016864 0.9197357395980656 1.0 1.0 30 P62995,Q8N5M9,P52789,Q15120,O95563 5 +Neutrophil mediated immunity 0.3510119306545265 0.0998706816731679 0.9204469925880344 1.0 1.0 6 Q8N5M9 1 +Positive regulation of proteasomal ubiquitin dependent protein catabolic process 0.2893272550378457 0.0986200450668668 0.9214399539446044 1.0 1.0 32 Q9H000,O75832,P54725,P31749,Q9UBS8,P10909,P04062 7 +Activation of adenylate cyclase activity 0.4582080577269903 0.0984716551343122 0.9215577784756448 1.0 1.0 3 P40123,P0DP25 2 +Detoxification 0.2887126645369394 0.0972709351520564 0.9225112369122288 1.0 1.0 27 P08183,P00374,P78417,Q6DKJ4 4 +Nucleoside triphosphate biosynthetic process 0.2866697888594522 0.096780253986904 0.9229009053481192 1.0 1.0 37 P00846,O75964 2 +Granulocyte chemotaxis 0.3049418995842134 0.0963559170668283 0.923237902239142 1.0 1.0 14 P04083,P35613 2 +Acrosome assembly 0.4346257889990974 0.0954052690385225 0.923992931083592 1.0 1.0 2 P82094 1 +Stem cell differentiation 0.2841441960684036 0.0949046314102069 0.9243905777934224 1.0 1.0 40 Q08J23,Q96PZ0,O75340,P28482,Q9Y5A9,Q9Y6C9 6 +Positive regulation of phagocytosis 0.348586121353944 0.0944985161996723 0.9247131610734812 1.0 1.0 6 Q92614 1 +Relaxation of cardiac muscle 0.454299458809385 0.0942699918957839 0.9248946867330816 1.0 1.0 3 P28161,P05023 2 +Leukocyte tethering or rolling 0.4539987973541658 0.0939534663575076 0.925146121621342 1.0 1.0 3 Q9H4A6,Q13464 2 +Regulation of cilium movement 0.4328223624887277 0.0938810820930132 0.9252036217597256 1.0 1.0 2 Q9Y6A4 1 +Vasculature development 0.2901503997559225 0.0935231340800177 0.9254879718980732 1.0 1.0 99 P42785,P31749,Q15363,P09601,Q96AY3,Q9NZ08,Q9H2J4,O95470 8 +Regulation of sprouting angiogenesis 0.3984288778273289 0.0920472881503402 0.926660468527592 1.0 1.0 4 P57105 1 +Positive regulation of cilium assembly 0.3205022648777654 0.0916164382949183 0.927002790508996 1.0 1.0 9 P42858,Q15555 2 +Regulation of histamine secretion by mast cell 0.4515935057125699 0.0914553508159868 0.9271307823860148 1.0 1.0 3 Q9UNH7,O95219 2 +Positive regulation of mast cell activation 0.4515935057125614 0.0914553508159781 0.9271307823860216 1.0 1.0 3 O95219,Q9NRA0 2 +Positive regulation of mast cell activation involved in immune response 0.4515935057125614 0.0914553508159781 0.9271307823860216 1.0 1.0 3 O95219,Q9NRA0 2 +Regulation of mononuclear cell migration 0.2944632357339302 0.0907857687676913 0.9276628182283284 1.0 1.0 18 P46108,P31749,P28482 3 +Regulation of peptidyl tyrosine phosphorylation 0.2876839764148911 0.0889295401249809 0.9291379069286712 1.0 1.0 28 P14174,O14641,P30153,Q9H2J4,O95684 5 +Regulation of platelet derived growth factor receptor beta signaling pathway 0.4259092275323111 0.0883557895699902 0.929593898625851 1.0 1.0 2 O00291 1 +Regulation of actin filament based movement 0.3356411800120495 0.0879968600120447 0.9298791718099086 1.0 1.0 7 P15924,P30626,P14923,Q9HD47,Q99996,P16615 6 +Positive regulation of protein glycosylation 0.4476849067949524 0.0875241269227207 0.930254908506118 1.0 1.0 3 Q9UHD1,Q08379 2 +Response to acidic ph 0.4476849067949462 0.0875241269227146 0.9302549085061228 1.0 1.0 3 Q9UHD1,Q15907 2 +Cellular response to acidic ph 0.4476849067949462 0.0875241269227146 0.9302549085061228 1.0 1.0 3 Q9UHD1,Q15907 2 +Vacuolar localization 0.2904294503174917 0.0873853055543668 0.930365249163958 1.0 1.0 21 Q9BZG1,Q86YV9,Q9NRA0,P09601,Q9H0B6,Q96AX1 6 +Regulation of hippo signaling 0.3945046526265128 0.086954753908085 0.9307074769708898 1.0 1.0 4 Q01085 1 +Taxis 0.2733658157088579 0.0865427494078201 0.9310349744113452 1.0 1.0 69 P14174,P11047,P46108,P11233,P42892,P04083,Q9NUQ9,Q9Y639,P35613 9 +Water homeostasis 0.3185224316358301 0.0851733459017167 0.9321235804515964 1.0 1.0 9 P04062 1 +Regulation of cell activation 0.2738794904879836 0.0846312247384774 0.932554574362013 1.0 1.0 68 P14174,O96028,O96005,Q92614,Q7KZ85,O15360,P31749,P04083,P09601,Q96FZ2,Q9NUQ9 11 +Ovarian follicle development 0.3434583326687275 0.0834617161266468 0.9334844172515137 1.0 1.0 6 Q9UI10,Q13144,P49770 3 +Magnesium ion transport 0.4180943793207117 0.0826942200103881 0.9340946808959516 1.0 1.0 2 Q8N4V1 1 +Negative regulation of endoplasmic reticulum unfolded protein response 0.3486762936221465 0.0826123404764951 0.9341597885380796 1.0 1.0 5 P63244,O76024,P18031,O94874 4 +Regulation of mrna binding 0.3423256309329644 0.0810824619307615 0.935376373110984 1.0 1.0 6 Q86X55,Q06787 2 +Muscle cell differentiation 0.2761991945117516 0.0810384702586397 0.9354113582577654 1.0 1.0 63 O75844,Q7KZ85,Q99523,Q8IV08,P09493,P31749,P41440,P67809 8 +Negative regulation of type i interferon mediated signaling pathway 0.3211512176586497 0.080862574802005 0.9355512434421625 1.0 1.0 8 Q9Y5A9 1 +Regulation of histone phosphorylation 0.3412830902684851 0.0789114385631685 0.9371030649577268 1.0 1.0 6 O43823,Q06787 2 +Epithelial tube formation 0.288382649547085 0.0785058016694135 0.937425715403563 1.0 1.0 22 Q15363,P11233,O60313 3 +Regulation of mitotic nuclear division 0.2834694479494326 0.0779713469658072 0.9378508453930549 1.0 1.0 38 Q96DY7,Q96EA4,P53350,Q9UJX4,O43683,Q9H900,O60566,O14757,Q9UJX3,Q15645 10 +Aspartate transmembrane transport 0.4371617558628965 0.0777116634867149 0.9380574160453778 1.0 1.0 3 Q9UJS0,O75746 2 +Hormone biosynthetic process 0.3161790054528226 0.077000521464564 0.9386231301321936 1.0 1.0 10 P30536 1 +Dna replication synthesis of rna primer 0.3862641793763171 0.0768857875990498 0.9387144039299516 1.0 1.0 4 Q14181 1 +Regulation of calcium ion dependent exocytosis 0.3452006900805812 0.0767282591453004 0.9388397232559196 1.0 1.0 5 Q00535 1 +Phagosome lysosome fusion 0.4353577871316876 0.0761398865455914 0.9393078073506904 1.0 1.0 3 Q9BZG1,Q9NVJ2 2 +Protein insertion into mitochondrial inner membrane 0.3397532350285933 0.0757583719635802 0.9396113352644248 1.0 1.0 6 Q9Y5J7,Q53H12,Q9P0J0,Q9Y5J9,O60220 5 +Establishment of centrosome localization 0.4347564642212922 0.0756229953305104 0.9397190412194508 1.0 1.0 3 Q9Y613,P15311 2 +Positive regulation of pseudopodium assembly 0.4045686804929387 0.0742626382352627 0.9408014052792052 1.0 1.0 2 P25054 1 +Pseudopodium organization 0.4045686804929387 0.0742626382352627 0.9408014052792052 1.0 1.0 2 P25054 1 +Regulation of synapse structural plasticity 0.40456868049293 0.074262638235258 0.9408014052792087 1.0 1.0 2 Q14012 1 +Atp metabolic process 0.2984594161990052 0.0715996045816096 0.942920554767563 1.0 1.0 113 Q9NTK5,Q9BSK2,O43676,P20674,O75964,Q9Y6M9,Q9UDW1,O75306,P34897,O75438,P30536,Q9BRR6,Q9H3K2,O95168,P00846,P14406,P52789,O14949 18 +Negative regulation of double strand break repair via nonhomologous end joining 0.3991584009618215 0.071340906863145 0.9431264391818814 1.0 1.0 2 Q9BRJ7 1 +Tumor necrosis factor superfamily cytokine production 0.2870298519839729 0.0712493737797891 0.9431992866386968 1.0 1.0 22 P14174,O43823,Q9NRA0,Q13546,P15260,P30536 6 +Intermediate filament bundle assembly 0.4288230230975455 0.0707086284477364 0.9436296535204864 1.0 1.0 3 P07196 1 +Pointed end actin filament capping 0.3958521190261458 0.0696740025373144 0.9444531344518472 1.0 1.0 2 Q9NYL9 1 +Rhythmic process 0.2741197649009977 0.0694923698885413 0.9445977059193508 1.0 1.0 65 P43490,Q9BWF3,Q06210,P04083,Q14103,Q9NRV9,Q00535,Q9BQG2,O95470,P42574 10 +Negative regulation of cell cell adhesion 0.2871145700227024 0.0694204554737237 0.9446549470827488 1.0 1.0 19 P04083,P31749,Q9Y5A9 3 +Platelet derived growth factor receptor beta signaling pathway 0.4260372820204341 0.0685159482286349 0.9453749250581682 1.0 1.0 3 O00291,P18031 2 +Positive regulation of amyloid beta clearance 0.4260372820204299 0.0685159482286315 0.9453749250581708 1.0 1.0 3 Q13464,P30533 2 +Negative regulation of phosphorus metabolic process 0.2855519685444484 0.0684630754484599 0.9454170126048902 1.0 1.0 96 P62942,O95373,Q86XL3,Q15363,P30153,P04062 6 +Insulin like growth factor receptor signaling pathway 0.336137382595185 0.0684612572535388 0.9454184599187394 1.0 1.0 6 Q6Y7W6,P31749 2 +Cell aging 0.284758264479404 0.0681442286889721 0.945670822757855 1.0 1.0 30 P14174,P67809,O60313,O75844 4 +Spermatid nucleus differentiation 0.3777443609022595 0.0673477147067363 0.946304892243026 1.0 1.0 4 P26583,Q96SB4,P82094 3 +Endocrine hormone secretion 0.4242333132892262 0.0671343506572078 0.9464747477007522 1.0 1.0 3 P82094,Q92930 2 +Receptor signaling pathway via stat 0.2959898760446482 0.0656907446645468 0.9476240411856638 1.0 1.0 15 P30153,Q9NX40,O95630,Q00535 4 +Regulation of the force of heart contraction 0.3743415007230846 0.0637802828915833 0.9491451782613988 1.0 1.0 4 P10253,P16615 2 +Histone h3 k9 demethylation 0.3731989868036831 0.0626129803850897 0.9500746928476308 1.0 1.0 4 O75151 1 +Positive regulation of filopodium assembly 0.3330932837155951 0.0624875739618938 0.9501745571438592 1.0 1.0 6 P11233 1 +Negative regulation of response to dna damage stimulus 0.2836504537176475 0.0622885443084163 0.9503330510803208 1.0 1.0 29 P14174,O95071,O75832,Q96FW1,Q96K76,P10909 6 +Regulation of mda 5 signaling pathway 0.4164866780332388 0.0615357704996915 0.9509325276328984 1.0 1.0 3 Q07021 1 +Mda 5 signaling pathway 0.4164866780332388 0.0615357704996915 0.9509325276328984 1.0 1.0 3 Q07021 1 +Regulation of heart rate by cardiac conduction 0.3354392298435683 0.0612043122870121 0.9511964954651576 1.0 1.0 5 P14923,P62258,P15924,Q99996 4 +Ethanol catabolic process 0.3751127141568949 0.0610785131174685 0.9512966812442514 1.0 1.0 2 P30837 1 +Primary alcohol catabolic process 0.3751127141568949 0.0610785131174685 0.9512966812442514 1.0 1.0 2 P30837 1 +Positive regulation of endocytosis 0.2844776378155735 0.0601144210981929 0.9520645043600052 1.0 1.0 23 P50897,Q06787,P41440 3 +Positive regulation of translational initiation 0.2946379057849139 0.0599959031434245 0.9521588976322156 1.0 1.0 15 Q7Z739,O00571,Q07666,Q9BYJ9,Q9Y5A9 5 +Regulation of brown fat cell differentiation 0.3345908202884625 0.0599244700458025 0.9522157906344062 1.0 1.0 5 Q92766 1 +Positive regulation of intrinsic apoptotic signaling pathway in response to dna damage 0.3688007213706014 0.0590321122370784 0.952926530835512 1.0 1.0 2 P23396 1 +Amine catabolic process 0.4121496537415036 0.0586314623541065 0.9532456504460656 1.0 1.0 3 P21964 1 +Developmental induction 0.3669972948602255 0.0584908302905542 0.9533576663593396 1.0 1.0 2 Q96C57 1 +Epidermis morphogenesis 0.3669972948602253 0.0584908302905542 0.9533576663593396 1.0 1.0 2 O60568 1 +Regulation of core promoter binding 0.3669972948602243 0.0584908302905536 0.9533576663593402 1.0 1.0 2 Q00403 1 +Positive regulation of protein exit from endoplasmic reticulum 0.3327316486161319 0.0571584377023272 0.954418985911104 1.0 1.0 5 Q9NR31,Q9Y6B6,Q92544,Q9NV96 4 +Regulation of chondrocyte differentiation 0.3672180451127861 0.0567484453554322 0.9547455823531432 1.0 1.0 4 P16435,Q06124,Q92896 3 +Negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 0.3522693116922055 0.0547234814911465 0.9563587618653242 1.0 1.0 2 P05141 1 +Cell cycle dna replication 0.2841547577400677 0.0547000917491508 0.9563773962685403 1.0 1.0 21 O75844 1 +Adherens junction assembly 0.3645112781954924 0.0542281828639044 0.95675336703598 1.0 1.0 4 Q13177,P35222,P18206 3 +Regulation of lipid transport 0.2840323402827364 0.0537460519780135 0.9571374916278488 1.0 1.0 20 P31749,P30536 2 +Energy derivation by oxidation of organic compounds 0.3056377138458278 0.0534296419057141 0.9573895881110248 1.0 1.0 126 P34897,O75438,O95168,P48735,P00846,O14949,O43676,Q9UDW1,P14406,P04062,Q9BSK2,Q15070,Q06210,O75874,P31749,P20674,O75964,O75306,Q9H3K2 19 +Limbic system development 0.2834386227020287 0.0522574225078659 0.9583235788502092 1.0 1.0 22 P46108,P07196,Q00535,O14949 4 +Guanine metabolic process 0.3387436128644395 0.0521527757974952 0.9584069611433634 1.0 1.0 2 O60341 1 +T helper 17 type immune response 0.336940186354063 0.0518649739151919 0.9586362834615918 1.0 1.0 2 P35232 1 +Tube formation 0.2828765986931104 0.0514841165570354 0.9589397582170568 1.0 1.0 23 Q15363,P11233,O60313 3 +Retina homeostasis 0.4002499504050807 0.0514666748875863 0.9589536562307248 1.0 1.0 3 Q15555 1 +Positive regulation of smad protein signal transduction 0.3994880165924011 0.051046429139798 0.959288523645569 1.0 1.0 3 Q93062 1 +Cytoplasmic sequestering of transcription factor 0.3265500188671373 0.0483400776378749 0.9614452145358724 1.0 1.0 5 O60826,O75832,Q9UN86 3 +Histone h4 acetylation 0.2826469567440171 0.048124973205829 0.9616166435206333 1.0 1.0 22 Q86UY6 1 +Aggresome assembly 0.2783288247670459 0.0471271685509771 0.9624118740170112 1.0 1.0 2 O95817 1 +Positive regulation of inclusion body assembly 0.3917618761274768 0.0470332511057343 0.9624867262937836 1.0 1.0 3 P10909,P62333 2 +Regulation of heart rate 0.3031109036112911 0.0464993030520371 0.9629122895710448 1.0 1.0 12 P16615,P0DP25,P09493 3 +Cellular response to extracellular stimulus 0.2733391965626476 0.0458362609186979 0.9634407571376872 1.0 1.0 52 Q9H773,O95831,Q96QD8,P28482,P21964,P09601,P49327,P04062 8 +Gpi anchor metabolic process 0.3240226669620318 0.0456092855983265 0.9636216680386072 1.0 1.0 6 Q9Y2B2 1 +Negative regulation of cell size 0.3530827067669213 0.0444753567119769 0.9645254950295834 1.0 1.0 4 Q96B36,P42345,P61586 3 +Ribonucleoprotein complex disassembly 0.3230987029669917 0.0436675695972141 0.9651693902587666 1.0 1.0 5 Q07866 1 +Minus end directed organelle transport along microtubule 0.3821407095610357 0.0426358912146068 0.9659917844404552 1.0 1.0 3 Q8TD16,P20340 2 +Regulation of hexokinase activity 0.3503759398496281 0.0423692595677409 0.9662043336457872 1.0 1.0 4 Q9NQ88,Q9Y6N1,Q9UNI6 3 +Ureter development 0.3796755839554886 0.0416101281215625 0.9668094991625034 1.0 1.0 3 Q9BRK4 1 +Positive regulation of map kinase activity 0.3013935259460822 0.0406272936736187 0.967593024910332 1.0 1.0 12 P14174 1 +Cell killing 0.281133438171471 0.0402802134421845 0.9678697283608556 1.0 1.0 22 Q9NUQ9 1 +Response to heat 0.2781086051354822 0.0388994837686506 0.9689705281518806 1.0 1.0 38 P31749,Q99543,P09601,O95391 4 +Inflammasome complex assembly 0.3704149128081822 0.0380999382372717 0.969608000555308 1.0 1.0 3 O00571,Q9H6R0 2 +Ubiquitin recycling 0.3441469168255371 0.0378066753224505 0.969841822041315 1.0 1.0 4 Q16763 1 +Positive regulation of dna damage response signal transduction by p53 class mediator 0.3689116055321749 0.0375790045825432 0.9700233480119008 1.0 1.0 3 P17844,O43324 2 +Morphogenesis of an endothelium 0.36710763680096 0.0369711155603486 0.9705080364326032 1.0 1.0 3 P61586,P67870 2 +Cellular response to gonadotropin stimulus 0.3662056524353633 0.0366741121218717 0.9707448502868335 1.0 1.0 3 P16435,P20248 2 +Response to gonadotropin 0.3662056524353633 0.0366741121218717 0.9707448502868335 1.0 1.0 3 P16435,P20248 2 +Protein k29 linked ubiquitination 0.3420404969459736 0.0363511917543404 0.9710023317703428 1.0 1.0 4 Q16763,Q15386 2 +Positive regulation of rna export from nucleus 0.3407518796992524 0.0354820760754941 0.9716953385950696 1.0 1.0 4 Q08211,Q07666,Q9H7Z3 3 +Positive regulation of nucleobase containing compound transport 0.3407518796992524 0.0354820760754941 0.9716953385950696 1.0 1.0 4 Q08211,Q07666,Q9H7Z3 3 +Second messenger mediated signaling 0.2788805983807285 0.0354096984104249 0.9717530513497048 1.0 1.0 28 P78417,P30153,O75844 3 +Negative regulation of wound healing 0.3130273991294194 0.0353004598984511 0.9718401566148044 1.0 1.0 7 P46108,O14936,P55011 3 +Positive regulation of potassium ion transmembrane transporter activity 0.3164861612515107 0.0352100766935403 0.9719122271751408 1.0 1.0 5 P05026,P35609,P50570,Q99996 4 +Ruffle assembly 0.2952352231604486 0.0350177248621226 0.972065607144602 1.0 1.0 13 Q9P258,Q9UJU6,P35241,P62330,P63000,Q8NCA5,P35080,O95429,Q9ULV4,P07737,Q7L576,P84095 12 +Cell activation 0.3102629691698213 0.0348031788750686 0.9722366857929908 1.0 1.0 136 P62942,P14174,O96005,Q92614,O15360,Q96FZ2,P24390,Q96L92,P17812,P09601,Q9NUQ9,P04062,O96028,P31749,Q9UQ84,P46379,P78536,Q7KZ85,P04083 19 +Cerebral cortex neuron differentiation 0.3389473684210559 0.0342918236451183 0.972644444822707 1.0 1.0 4 Q96ST3,P43034,P50542 3 +Negative regulation of supramolecular fiber organization 0.2722179768488707 0.033134144265827 0.9735676145038789 1.0 1.0 54 Q9UHB6,Q6ZU35,Q13177,P61758,P25054,Q9UHV9,P35080,Q02790,Q9UJX6,O15020,P10909,Q9NUQ9,O60925 13 +Endoplasmic reticulum unfolded protein response 0.2794809812502424 0.0311454896842368 0.9751535117281374 1.0 1.0 21 Q15363,P57088,Q7Z2K6,Q9BUN8 4 +Regulation of system process 0.2720396199877341 0.0307953908332798 0.9754327162604816 1.0 1.0 58 P78417,Q9UQB8,O75844,P09493,P42892,Q01469,Q06787,P04062 8 +Scarna localization to cajal body 0.3126250974003161 0.0305678385818313 0.9756141912514088 1.0 1.0 5 Q9BUR4 1 +Positive regulation of peptidyl threonine phosphorylation 0.3104444718030383 0.0298956051671073 0.976150310853062 1.0 1.0 7 P28482,P0DP25 2 +Secretory granule organization 0.311371841155239 0.0291072757369778 0.9767790330589092 1.0 1.0 5 P43034,P22059,P82094,P78537 4 +Interleukin 2 production 0.3019851129660159 0.0289744986826887 0.9768849291560996 1.0 1.0 8 Q01082,Q92990,P14373,P23396,P04083,Q9UJZ1 6 +Cellular response to vitamin 0.3137274692120705 0.028123460968437 0.9775636823251844 1.0 1.0 6 Q8TB36,O15164,Q96C86 3 +Regulation of dendrite extension 0.3280216476247748 0.027721366345404 0.9778843823716644 1.0 1.0 3 Q9Y263,O60271 2 +Hippo signaling 0.3089742559740592 0.0268759951225933 0.978558639717265 1.0 1.0 7 Q13043,Q01085 2 +Positive regulation of centriole replication 0.3220084185207515 0.0268394385692542 0.9785877971087202 1.0 1.0 3 P37198,Q6UVJ0 2 +Sodium ion export across plasma membrane 0.3162958508719237 0.0261043846911791 0.9791740797778694 1.0 1.0 3 P05026,P05023 2 +Dna modification 0.2779683354164036 0.0258300738255894 0.9793928744029824 1.0 1.0 30 Q9NRW3,O75844 2 +Regulation of apoptotic signaling pathway 0.2838469629767693 0.0247012859180797 0.9802932293802932 1.0 1.0 99 P14174,P30154,O75832,Q13043,P16989,P30153,Q9Y3D6,O00571,Q9UL15,P61978,P42858,P09601,O95881,O60341,Q96K76,Q8N2F6,Q7LG56,P45880,Q13546,P31749,P49327,O60313,Q9H3K2,P10909 24 +Positive regulation of intracellular lipid transport 0.2856283824413775 0.0235062012836898 0.9812464919437628 1.0 1.0 3 Q5SW96,P22307 2 +Regulation of intracellular lipid transport 0.2856283824413775 0.0235062012836898 0.9812464919437628 1.0 1.0 3 Q5SW96,P22307 2 +Positive regulation of striated muscle cell apoptotic process 0.268190018039694 0.0227470680682857 0.9818520306462032 1.0 1.0 3 P17655,Q9NQ88 2 +Positive regulation of ubiquitin dependent protein catabolic process 0.2774842879533714 0.0224615828532682 0.9820797567044536 1.0 1.0 34 Q9H000,P53350,O75832,P54725,P48729,P31749,O60826,Q9UBS8,P10909,P04062 10 +Neuroinflammatory response 0.2543595911004285 0.0223755096401719 0.982148415936329 1.0 1.0 3 P53634,P05556 2 +Dendritic cell chemotaxis 0.2540589296452262 0.0223691544110889 0.9821534854066472 1.0 1.0 3 P09429,Q07021 2 +Macrophage apoptotic process 0.2459410703547874 0.0222201614580231 0.982272335042575 1.0 1.0 3 P42771,P17987 2 +Regulation of macrophage apoptotic process 0.2459410703547874 0.0222201614580231 0.982272335042575 1.0 1.0 3 P42771,P17987 2 +Glial cell apoptotic process 0.3050697100854456 0.0221008424764612 0.9823675144421248 1.0 1.0 5 Q00535 1 +Cellular potassium ion homeostasis 0.316390977443613 0.0218780792085854 0.9825452108473768 1.0 1.0 4 P05026,P55011,P05023 3 +Cellular sodium ion homeostasis 0.316390977443613 0.0218780792085854 0.9825452108473768 1.0 1.0 4 P05026,P55011,P05023 3 +Potassium ion homeostasis 0.316390977443613 0.0218780792085854 0.9825452108473768 1.0 1.0 4 P05026,P55011,P05023 3 +Negative regulation of response to cytokine stimulus 0.2983590753237836 0.0217436493571966 0.9826524448408512 1.0 1.0 10 Q9Y5A9 1 +Hindbrain development 0.2773615720519521 0.0216517626303692 0.982725742585534 1.0 1.0 34 O14949,Q5KU26,P46108,O94992,O94788,O95456,Q14103,Q00535,O15020,O15228,Q15058,P54802,P04062 13 +Regulation of smad protein signal transduction 0.3008246099338689 0.0176935693319939 0.9858833107757744 1.0 1.0 5 Q93062 1 +Oogenesis 0.2841133869418019 0.0173931057001125 0.9861230091791636 1.0 1.0 15 Q15645,Q9H6S0,Q9Y5A9,P30153 4 +Protein stabilization 0.2651729852382135 0.0168105330085614 0.9865877669593855 1.0 1.0 77 P46379,Q32P28,O15027,Q969V3,O75718,Q9H2J4,P41440,Q96JB2 8 +Mrna 5 splice site recognition 0.2993381468110803 0.0162085489239574 0.9870680153051984 1.0 1.0 5 Q07955,Q86UA1,O75475,P09234 4 +Intermediate filament based process 0.2933037645109122 0.0139404630647749 0.9888774800032942 1.0 1.0 12 P08670,P07196 2 +Positive regulation of leukocyte degranulation 0.3042431537767136 0.01357384724463 0.9891699694248122 1.0 1.0 6 P51809,Q9NRA0,P11279,O95219,Q12846 5 +Protein deneddylation 0.2953929539295349 0.0129247892764253 0.9896877972947252 1.0 1.0 8 Q9BT78,P61201,Q92905,Q9UBW8,Q13098,Q99627,Q9UNS2 7 +Regulation of response to cytokine stimulus 0.2754566236640796 0.0126340979063684 0.9899197165114142 1.0 1.0 29 Q7Z739,P78536,Q8TCT8,Q13546,Q9Y3Z3,Q9Y5A9 6 +Cellular response to toxic substance 0.2736420481466347 0.0121707069522248 0.9902894205610782 1.0 1.0 26 P00374,P78417 2 +Regulation of receptor catabolic process 0.2857142857142907 0.011153147454275 0.9911012603319648 1.0 1.0 4 Q96J02,Q13614,P18031 3 +Cell death in response to hydrogen peroxide 0.2946180215137319 0.011099795685863 0.99114382624939 1.0 1.0 8 Q99720 1 +Negative regulation of response to stimulus 0.3495857530405704 0.009791059462019 0.992187989637746 1.0 1.0 261 P62942,Q8N183,P28070,P14174,Q9UJ14,P25786,Q7Z739,O75832,P16989,Q9Y4E8,Q8N0X7,P30153,Q9UJX6,Q9P253,Q04323,Q9Y5A9,P50402,Q9UL15,Q96G23,Q9UMX5,Q9NPR9,Q8IWV7,P42858,Q96FW1,P80303,Q9Y5X3,P30086,Q9BRK4,P09601,O95881,Q96K76,Q8N2F6,P67809,Q9NUQ9,Q7LG56,P04062,P19474,Q9H000,P45880,Q13546,Q6DKJ4,P57105,O95071,P31749,O75340,O60313,P78536,P46108,O43657,P04083,Q9H3K2,Q8N5M9,O95140 53 +Response to electrical stimulus 0.3008280515959252 0.0086960672549683 0.9930616296460956 1.0 1.0 6 Q7L576,Q14103 2 +Regulation of histone h2b ubiquitination 0.2718796992481238 0.0080991939802584 0.993537848817842 1.0 1.0 4 Q6PD62,Q5VTR2,O75150 3 +Tripartite regional subdivision 0.2700751879699288 0.0077661290090507 0.9938035878536572 1.0 1.0 4 Q9UK61,Q8NHU6,Q9Y2W6 3 +Blastoderm segmentation 0.2700751879699288 0.0077661290090507 0.9938035878536572 1.0 1.0 4 Q9UK61,Q8NHU6,Q9Y2W6 3 +Receptor clustering 0.2873298654249557 0.0073540681325496 0.994132355467297 1.0 1.0 13 P57105,Q00535,Q14168 3 +Negative regulation of dna biosynthetic process 0.2909627127366884 0.0065234367615471 0.9947950874406531 1.0 1.0 12 Q99543,O14757 2 +Signal transduction by p53 class mediator 0.2689112628058616 0.0060602814415089 0.9951646246018656 1.0 1.0 53 P14174,P46379,P61978,O75844,O75832,O94992,P31749,O14757,Q8N2F6,Q7LG56 10 +Fructose 6 phosphate metabolic process 0.298228283838382 0.0060596984135581 0.9951650897823244 1.0 1.0 7 Q06210 1 +Dendritic cell migration 0.2541353383458688 0.0053749316655521 0.9957114456580064 1.0 1.0 4 P09429,Q07021,P60953 3 +Pyrimidine nucleobase metabolic process 0.2819384462103823 0.0052574984085768 0.9958051425165716 1.0 1.0 14 P28482,P17812 2 +Execution phase of apoptosis 0.2809387382978065 0.0051662520212823 0.9958779456113922 1.0 1.0 15 O95831 1 +Regulation of nuclear division 0.2727461321196465 0.0048311081057003 0.9961453484252392 1.0 1.0 39 Q96DY7,Q96EA4,P53350,Q9UJX4,O43683,Q9H900,O60566,O14757,Q9UJX3,Q15645 10 +Regulation of morphogenesis of an epithelium 0.2279699248120346 0.0030994108524838 0.9975270318925842 1.0 1.0 4 P35222,P35453,Q99623 3 +Intestinal epithelial cell differentiation 0.2234586466165454 0.0028562128126496 0.99772107499298 1.0 1.0 4 Q9NQ88,P04818,Q99626 3 +Protein targeting to peroxisome 0.2836943441636635 0.0023374718672636 0.998134968984151 1.0 1.0 5 Q9UJ83,P40855,Q92930,P50542 4 +Columnar cuboidal epithelial cell development 0.2913886948259214 0.0021060718484128 0.9983195990304572 1.0 1.0 10 P31749 1 +Actin filament polymerization 0.2662013522823883 0.0017931901103432 0.9985692420631472 1.0 1.0 47 O95429,Q9NUQ9,Q9UQB8,Q6ZU35 4 +Locomotory behavior 0.2739594337101704 0.0015989213345785 0.9987242458967897 1.0 1.0 30 P50897,Q8N2K0 2 +Nucleobase metabolic process 0.2722250693605745 0.0004751354200438 0.9996208967983204 1.0 1.0 25 P17812,P34896,P34897,P28482,Q06203 5 diff --git a/msigdb_gobp/selections.json b/msigdb_gobp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..ff91f400f8e940182048cd093c974bf06e84c621 --- /dev/null +++ b/msigdb_gobp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["10 formyltetrahydrofolate metabolic process", "2 oxoglutarate metabolic process", "2fe 2s cluster assembly", "3 phosphoadenosine 5 phosphosulfate biosynthetic process", "3 phosphoadenosine 5 phosphosulfate metabolic process", "3 utr mediated mrna destabilization", "3 utr mediated mrna stabilization", "5 phosphoribose 1 diphosphate metabolic process", "5s class rrna transcription by rna polymerase iii", "Abscission", "Acetyl coa biosynthetic process", "Acetyl coa biosynthetic process from pyruvate", "Acetyl coa metabolic process", "Acid secretion", "Acidic amino acid transport", "Acrosome assembly", "Acrosome reaction", "Actin crosslink formation", "Actin cytoskeleton reorganization", "Actin filament based movement", "Actin filament based process", "Actin filament based transport", "Actin filament bundle organization", "Actin filament depolymerization", "Actin filament network formation", "Actin filament organization", "Actin filament polymerization", "Actin filament reorganization", "Actin filament severing", "Actin mediated cell contraction", "Actin modification", "Actin myosin filament sliding", "Actin nucleation", "Actin polymerization dependent cell motility", "Actin polymerization or depolymerization", "Action potential", "Activated t cell proliferation", "Activation induced cell death of t cells", "Activation of adenylate cyclase activity", "Activation of cysteine type endopeptidase activity", "Activation of cysteine type endopeptidase activity involved in apoptotic process", "Activation of cysteine type endopeptidase activity involved in apoptotic process by cytochrome c", "Activation of gtpase activity", "Activation of immune response", "Activation of innate immune response", "Activation of janus kinase activity", "Activation of nf kappab inducing kinase activity", "Activation of phospholipase c activity", "Activation of phospholipase d activity", "Activation of protein kinase activity", "Activation of protein kinase b activity", "Activation of protein kinase c activity", "Activin receptor signaling pathway", "Actomyosin contractile ring organization", "Actomyosin structure organization", "Acute inflammatory response", "Acute inflammatory response to antigenic stimulus", "Acute phase response", "Acyl carnitine transmembrane transport", "Acylglycerol homeostasis", "Adaptation of signaling pathway", "Adaptive immune response", "Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains", "Adaptive thermogenesis", "Adenosine metabolic process", "Adenosine to inosine editing", "Adenylate cyclase activating adrenergic receptor signaling pathway", "Adenylate cyclase activating adrenergic receptor signaling pathway involved in heart process", "Adenylate cyclase activating dopamine receptor signaling pathway", "Adenylate cyclase activating g protein coupled receptor signaling pathway", "Adenylate cyclase inhibiting dopamine receptor signaling pathway", "Adenylate cyclase inhibiting g protein coupled receptor signaling pathway", "Adenylate cyclase modulating g protein coupled receptor signaling pathway", "Adherens junction assembly", "Adherens junction maintenance", "Adherens junction organization", "Adhesion of symbiont to host", "Adhesion of symbiont to host cell", "Adiponectin activated signaling pathway", "Adipose tissue development", "Adp biosynthetic process", "Adp metabolic process", "Adp transport", "Adrenal gland development", "Adrenergic receptor signaling pathway", "Adult behavior", "Adult locomotory behavior", "Aerobic respiration", "Aggrephagy", "Aggresome assembly", "Aging", "Alanine catabolic process", "Alanine transport", "Alcohol biosynthetic process", "Alcohol catabolic process", "Alcohol metabolic process", "Aldehyde biosynthetic process", "Aldehyde catabolic process", "Alditol biosynthetic process", "Alditol catabolic process", "Alditol metabolic process", "Alditol phosphate metabolic process", "Alkanesulfonate metabolic process", "Allantoin metabolic process", "Alpha amino acid catabolic process", "Alpha amino acid metabolic process", "Alpha beta t cell activation", "Alpha beta t cell differentiation", "Alpha beta t cell proliferation", "Alpha ketoglutarate transport", "Alpha linolenic acid metabolic process", "Alternative mrna splicing via spliceosome", "Ameboidal type cell migration", "Amide biosynthetic process", "Amide transport", "Amine biosynthetic process", "Amine catabolic process", "Amine metabolic process", "Amine transport", "Amino acid activation", "Amino acid betaine biosynthetic process", "Amino acid betaine metabolic process", "Amino acid betaine transport", "Amino acid homeostasis", "Amino acid import", "Amino acid import across plasma membrane", "Amino acid neurotransmitter reuptake", "Amino acid salvage", "Amino acid transmembrane transport", "Amino acid transport", "Amino sugar biosynthetic process", "Amino sugar catabolic process", "Amino sugar metabolic process", "Aminoacyl trna metabolism involved in translational fidelity", "Aminoglycan biosynthetic process", "Aminoglycan catabolic process", "Aminoglycan metabolic process", "Aminoglycoside antibiotic metabolic process", "Aminophospholipid translocation", "Aminophospholipid transport", "Ammonium ion metabolic process", "Ammonium transmembrane transport", "Amp biosynthetic process", "Amp catabolic process", "Amp metabolic process", "Amp salvage", "Ampa glutamate receptor clustering", "Amygdala development", "Amyloid beta clearance", "Amyloid beta clearance by cellular catabolic process", "Amyloid beta clearance by transcytosis", "Amyloid beta formation", "Amyloid beta metabolic process", "Amyloid fibril formation", "Amyloid precursor protein biosynthetic process", "Amyloid precursor protein catabolic process", "Amyloid precursor protein metabolic process", "Anagen", "Anaphase promoting complex dependent catabolic process", "Anatomical structure arrangement", "Anatomical structure formation involved in morphogenesis", "Anatomical structure homeostasis", "Anatomical structure maturation", "Androgen biosynthetic process", "Androgen catabolic process", "Androgen metabolic process", "Androgen receptor signaling pathway", "Angiogenesis involved in wound healing", "Angiotensin activated signaling pathway", "Animal organ formation", "Animal organ maturation", "Animal organ morphogenesis", "Animal organ regeneration", "Anion homeostasis", "Anion transmembrane transport", "Anion transport", "Anoikis", "Anterior head development", "Anterior posterior axis specification", "Anterior posterior pattern specification", "Anterograde axonal transport", "Anterograde axonal transport of mitochondrion", "Anterograde dendritic transport", "Anterograde dendritic transport of neurotransmitter receptor complex", "Anterograde neuronal dense core vesicle transport", "Antibacterial humoral response", "Antifungal innate immune response", "Antigen processing and presentation", "Antigen processing and presentation of endogenous antigen", "Antigen processing and presentation of endogenous peptide antigen", "Antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway", "Antigen processing and presentation of exogenous antigen", "Antigen processing and presentation of exogenous peptide antigen", "Antigen processing and presentation of exogenous peptide antigen via mhc class i", "Antigen processing and presentation of exogenous peptide antigen via mhc class ii", "Antigen processing and presentation of lipid antigen via mhc class ib", "Antigen processing and presentation of peptide antigen", "Antigen processing and presentation of peptide antigen via mhc class i", "Antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii", "Antigen processing and presentation via mhc class ib", "Antigen receptor mediated signaling pathway", "Antimicrobial humoral immune response mediated by antimicrobial peptide", "Antimicrobial humoral response", "Antiviral innate immune response", "Aorta development", "Aorta morphogenesis", "Aortic valve morphogenesis", "Apical junction assembly", "Apical protein localization", "Apolipoprotein a i mediated signaling pathway", "Apoptotic cell clearance", "Apoptotic chromosome condensation", "Apoptotic dna fragmentation", "Apoptotic mitochondrial changes", "Apoptotic process involved in blood vessel morphogenesis", "Apoptotic process involved in development", "Apoptotic process involved in heart morphogenesis", "Apoptotic process involved in morphogenesis", "Apoptotic signaling pathway", "Appendage development", "Appendage morphogenesis", "Arachidonic acid metabolic process", "Arachidonic acid secretion", "Arf protein signal transduction", "Arginine catabolic process", "Arginine metabolic process", "Aromatic amino acid family catabolic process", "Aromatic amino acid family metabolic process", "Aromatic amino acid transport", "Arp2 3 complex mediated actin nucleation", "Artery development", "Artery morphogenesis", "Asparagine metabolic process", "Aspartate family amino acid biosynthetic process", "Aspartate family amino acid catabolic process", "Aspartate family amino acid metabolic process", "Aspartate metabolic process", "Aspartate transmembrane transport", "Associative learning", "Astral microtubule organization", "Astrocyte activation", "Astrocyte cell migration", "Astrocyte development", "Astrocyte differentiation", "Asymmetric cell division", "Asymmetric neuroblast division", "Atf6 mediated unfolded protein response", "Atp biosynthetic process", "Atp metabolic process", "Atp synthesis coupled electron transport", "Atp synthesis coupled proton transport", "Atp transport", "Atrial cardiac muscle cell membrane repolarization", "Atrial cardiac muscle cell to av node cell signaling", "Atrial septum development", "Atrial septum morphogenesis", "Atrioventricular canal development", "Atrioventricular valve development", "Attachment of gpi anchor to protein", "Attachment of mitotic spindle microtubules to kinetochore", "Attachment of spindle microtubules to kinetochore", "Auditory receptor cell development", "Auditory receptor cell morphogenesis", "Autonomic nervous system development", "Autophagic cell death", "Autophagosome lysosome fusion", "Autophagosome maturation", "Autophagosome membrane docking", "Autophagosome organization", "Autophagy of mitochondrion", "Autophagy of nucleus", "Autophagy of peroxisome", "Axial mesoderm development", "Axis elongation", "Axis specification", "Axo dendritic protein transport", "Axo dendritic transport", "Axon development", "Axon ensheathment in central nervous system", "Axon extension", "Axonal fasciculation", "Axonal transport", "Axonal transport of mitochondrion", "Axonemal dynein complex assembly", "Axoneme assembly", "Axonogenesis involved in innervation", "B cell activation", "B cell activation involved in immune response", "B cell apoptotic process", "B cell differentiation", "B cell homeostasis", "B cell lineage commitment", "B cell mediated immunity", "B cell proliferation", "B cell receptor signaling pathway", "Barbed end actin filament capping", "Base conversion or substitution editing", "Base excision repair", "Base excision repair ap site formation", "Base excision repair gap filling", "Basement membrane assembly", "Basement membrane organization", "Behavior", "Behavioral response to cocaine", "Behavioral response to ethanol", "Behavioral response to pain", "Benzene containing compound metabolic process", "Bergmann glial cell differentiation", "Bile acid and bile salt transport", "Bile acid biosynthetic process", "Bile acid metabolic process", "Bile acid secretion", "Bile acid signaling pathway", "Binding of sperm to zona pellucida", "Biological adhesion", "Biological phase", "Biological process involved in interaction with host", "Biological process involved in interaction with symbiont", "Biological process involved in interspecies interaction between organisms", "Biological process involved in intraspecies interaction between organisms", "Biological process involved in symbiotic interaction", "Biomineralization", "Blastocyst development", "Blastocyst formation", "Blastocyst growth", "Blastoderm segmentation", "Bleb assembly", "Blood vessel endothelial cell migration", "Blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Blood vessel maturation", "Blood vessel morphogenesis", "Blood vessel remodeling", "Body fluid secretion", "Body morphogenesis", "Bone cell development", "Bone development", "Bone growth", "Bone marrow development", "Bone maturation", "Bone mineralization", "Bone morphogenesis", "Bone remodeling", "Bone resorption", "Box c d snornp assembly", "Bradykinin catabolic process", "Brain derived neurotrophic factor receptor signaling pathway", "Brain morphogenesis", "Brainstem development", "Branch elongation of an epithelium", "Branched chain amino acid biosynthetic process", "Branched chain amino acid catabolic process", "Branched chain amino acid metabolic process", "Branched chain amino acid transport", "Branching involved in blood vessel morphogenesis", "Branching involved in labyrinthine layer morphogenesis", "Branching involved in mammary gland duct morphogenesis", "Branching involved in prostate gland morphogenesis", "Branching morphogenesis of a nerve", "Branching morphogenesis of an epithelial tube", "Branchiomotor neuron axon guidance", "Brown fat cell differentiation", "Bud elongation involved in lung branching", "Bundle of his cell to purkinje myocyte communication", "Bundle of his cell to purkinje myocyte signaling", "C 5 methylation of cytosine", "C terminal protein amino acid modification", "C terminal protein lipidation", "C21 steroid hormone biosynthetic process", "C21 steroid hormone metabolic process", "C4 dicarboxylate transport", "Calcineurin mediated signaling", "Calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules", "Calcium import into the mitochondrion", "Calcium ion export", "Calcium ion export across plasma membrane", "Calcium ion import", "Calcium ion import into sarcoplasmic reticulum", "Calcium ion regulated exocytosis", "Calcium ion regulated exocytosis of neurotransmitter", "Calcium ion transmembrane transport", "Calcium ion transmembrane transport via high voltage gated calcium channel", "Calcium ion transport", "Calcium ion transport into cytosol", "Calcium mediated signaling", "Calcium mediated signaling using intracellular calcium source", "Calmodulin dependent kinase signaling pathway", "Camera type eye development", "Camera type eye morphogenesis", "Camera type eye photoreceptor cell differentiation", "Camp mediated signaling", "Cannabinoid signaling pathway", "Canonical wnt signaling pathway", "Canonical wnt signaling pathway involved in heart development", "Canonical wnt signaling pathway involved in osteoblast differentiation", "Canonical wnt signaling pathway involved in regulation of cell proliferation", "Cap dependent translational initiation", "Carbohydrate biosynthetic process", "Carbohydrate catabolic process", "Carbohydrate derivative biosynthetic process", "Carbohydrate derivative catabolic process", "Carbohydrate derivative metabolic process", "Carbohydrate derivative transport", "Carbohydrate homeostasis", "Carbohydrate mediated signaling", "Carbohydrate metabolic process", "Carbohydrate phosphorylation", "Carbohydrate transmembrane transport", "Carbohydrate transport", "Carboxylic acid transport", "Cardiac atrium development", "Cardiac atrium morphogenesis", "Cardiac cell development", "Cardiac chamber development", "Cardiac chamber morphogenesis", "Cardiac conduction", "Cardiac conduction system development", "Cardiac epithelial to mesenchymal transition", "Cardiac left ventricle morphogenesis", "Cardiac muscle cell action potential", "Cardiac muscle cell action potential involved in contraction", "Cardiac muscle cell cardiac muscle cell adhesion", "Cardiac muscle cell contraction", "Cardiac muscle cell differentiation", "Cardiac muscle cell membrane repolarization", "Cardiac muscle cell proliferation", "Cardiac muscle contraction", "Cardiac muscle tissue development", "Cardiac muscle tissue morphogenesis", "Cardiac muscle tissue regeneration", "Cardiac neural crest cell development involved in outflow tract morphogenesis", "Cardiac neural crest cell differentiation involved in heart development", "Cardiac neural crest cell migration involved in outflow tract morphogenesis", "Cardiac septum development", "Cardiac septum morphogenesis", "Cardiac ventricle development", "Cardiac ventricle morphogenesis", "Cardioblast differentiation", "Cardioblast proliferation", "Cardiocyte differentiation", "Cardiolipin acyl chain remodeling", "Cardiolipin biosynthetic process", "Cardiolipin metabolic process", "Carnitine metabolic process", "Carnitine transport", "Cartilage development", "Cartilage development involved in endochondral bone morphogenesis", "Catechol containing compound biosynthetic process", "Catechol containing compound catabolic process", "Catechol containing compound metabolic process", "Catecholamine uptake", "Catecholamine uptake involved in synaptic transmission", "Cation transmembrane transport", "Cation transport", "Caveola assembly", "Caveolin mediated endocytosis", "Cd4 positive alpha beta t cell activation", "Cd4 positive alpha beta t cell differentiation", "Cd4 positive or cd8 positive alpha beta t cell lineage commitment", "Cd40 signaling pathway", "Cd8 positive alpha beta t cell activation", "Cd8 positive alpha beta t cell proliferation", "Cdc42 protein signal transduction", "Cdp choline pathway", "Cdp diacylglycerol metabolic process", "Cell activation", "Cell activation involved in immune response", "Cell adhesion mediated by integrin", "Cell adhesion molecule production", "Cell aggregation", "Cell aging", "Cell cell adhesion", "Cell cell adhesion involved in gastrulation", "Cell cell adhesion mediated by cadherin", "Cell cell adhesion mediated by integrin", "Cell cell adhesion via plasma membrane adhesion molecules", "Cell cell junction assembly", "Cell cell junction maintenance", "Cell cell junction organization", "Cell cell recognition", "Cell cell signaling", "Cell cell signaling by wnt", "Cell cell signaling involved in cardiac conduction", "Cell chemotaxis", "Cell communication by electrical coupling", "Cell communication by electrical coupling involved in cardiac conduction", "Cell communication involved in cardiac conduction", "Cell cycle", "Cell cycle checkpoint signaling", "Cell cycle dna replication", "Cell cycle dna replication initiation", "Cell cycle g1 s phase transition", "Cell cycle g2 m phase transition", "Cell cycle phase transition", "Cell cycle process", "Cell death in response to hydrogen peroxide", "Cell death in response to oxidative stress", "Cell differentiation in spinal cord", "Cell differentiation involved in embryonic placenta development", "Cell differentiation involved in kidney development", "Cell differentiation involved in metanephros development", "Cell differentiation involved in phenotypic switching", "Cell division", "Cell fate commitment", "Cell fate commitment involved in formation of primary germ layer", "Cell fate determination", "Cell fate specification", "Cell growth", "Cell junction assembly", "Cell junction disassembly", "Cell junction maintenance", "Cell junction organization", "Cell killing", "Cell matrix adhesion", "Cell maturation", "Cell migration", "Cell migration in hindbrain", "Cell migration involved in gastrulation", "Cell migration involved in heart development", "Cell migration involved in sprouting angiogenesis", "Cell morphogenesis", "Cell morphogenesis involved in differentiation", "Cell morphogenesis involved in neuron differentiation", "Cell motility involved in cerebral cortex radial glia guided migration", "Cell part morphogenesis", "Cell projection assembly", "Cell projection organization", "Cell proliferation in forebrain", "Cell proliferation in hindbrain", "Cell proliferation involved in heart morphogenesis", "Cell proliferation involved in kidney development", "Cell proliferation involved in metanephros development", "Cell recognition", "Cell redox homeostasis", "Cell substrate adhesion", "Cell substrate junction organization", "Cell surface receptor signaling pathway involved in cell cell signaling", "Cell surface receptor signaling pathway involved in heart development", "Cell volume homeostasis", "Cellular aldehyde metabolic process", "Cellular amide metabolic process", "Cellular amino acid biosynthetic process", "Cellular amino acid catabolic process", "Cellular amino acid metabolic process", "Cellular anion homeostasis", "Cellular carbohydrate biosynthetic process", "Cellular carbohydrate catabolic process", "Cellular carbohydrate metabolic process", "Cellular component assembly involved in morphogenesis", "Cellular component disassembly", "Cellular component disassembly involved in execution phase of apoptosis", "Cellular component maintenance", "Cellular component morphogenesis", "Cellular copper ion homeostasis", "Cellular defense response", "Cellular detoxification of aldehyde", "Cellular extravasation", "Cellular glucan metabolic process", "Cellular glucose homeostasis", "Cellular homeostasis", "Cellular hormone metabolic process", "Cellular hyperosmotic response", "Cellular hyperosmotic salinity response", "Cellular hypotonic response", "Cellular ion homeostasis", "Cellular iron ion homeostasis", "Cellular ketone metabolic process", "Cellular lipid catabolic process", "Cellular lipid metabolic process", "Cellular macromolecule biosynthetic process", "Cellular macromolecule localization", "Cellular metabolic compound salvage", "Cellular modified amino acid biosynthetic process", "Cellular modified amino acid catabolic process", "Cellular modified amino acid metabolic process", "Cellular monovalent inorganic anion homeostasis", "Cellular monovalent inorganic cation homeostasis", "Cellular nitrogen compound catabolic process", "Cellular oxidant detoxification", "Cellular pigmentation", "Cellular polysaccharide catabolic process", "Cellular potassium ion homeostasis", "Cellular process involved in reproduction in multicellular organism", "Cellular protein catabolic process", "Cellular respiration", "Cellular response to abiotic stimulus", "Cellular response to acid chemical", "Cellular response to acidic ph", "Cellular response to alcohol", "Cellular response to aldehyde", "Cellular response to alkaloid", "Cellular response to amyloid beta", "Cellular response to antibiotic", "Cellular response to arsenic containing substance", "Cellular response to atp", "Cellular response to biotic stimulus", "Cellular response to brain derived neurotrophic factor stimulus", "Cellular response to cadmium ion", "Cellular response to caffeine", "Cellular response to calcium ion", "Cellular response to camp", "Cellular response to carbohydrate stimulus", "Cellular response to chemical stress", "Cellular response to cocaine", "Cellular response to cold", "Cellular response to copper ion", "Cellular response to corticosteroid stimulus", "Cellular response to dexamethasone stimulus", "Cellular response to dna damage stimulus", "Cellular response to dsrna", "Cellular response to electrical stimulus", "Cellular response to endogenous stimulus", "Cellular response to epinephrine stimulus", "Cellular response to estradiol stimulus", "Cellular response to estrogen stimulus", "Cellular response to ethanol", "Cellular response to ether", "Cellular response to exogenous dsrna", "Cellular response to external stimulus", "Cellular response to extracellular stimulus", "Cellular response to fatty acid", "Cellular response to fluid shear stress", "Cellular response to follicle stimulating hormone stimulus", "Cellular response to gamma radiation", "Cellular response to glucose starvation", "Cellular response to gonadotropin stimulus", "Cellular response to growth hormone stimulus", "Cellular response to heat", "Cellular response to heparin", "Cellular response to histamine", "Cellular response to hormone stimulus", "Cellular response to hydrogen peroxide", "Cellular response to hydroperoxide", "Cellular response to hyperoxia", "Cellular response to increased oxygen levels", "Cellular response to indole 3 methanol", "Cellular response to inorganic substance", "Cellular response to insulin like growth factor stimulus", "Cellular response to insulin stimulus", "Cellular response to interferon alpha", "Cellular response to interferon beta", "Cellular response to interferon gamma", "Cellular response to interleukin 1", "Cellular response to ionizing radiation", "Cellular response to iron ion", "Cellular response to ketone", "Cellular response to leptin stimulus", "Cellular response to leucine", "Cellular response to leucine starvation", "Cellular response to light stimulus", "Cellular response to lipid", "Cellular response to lipoprotein particle stimulus", "Cellular response to lithium ion", "Cellular response to low density lipoprotein particle stimulus", "Cellular response to magnesium ion", "Cellular response to manganese ion", "Cellular response to mechanical stimulus", "Cellular response to mineralocorticoid stimulus", "Cellular response to molecule of bacterial origin", "Cellular response to muramyl dipeptide", "Cellular response to nicotine", "Cellular response to nitrogen compound", "Cellular response to nitrogen starvation", "Cellular response to nitrosative stress", "Cellular response to nutrient", "Cellular response to organic cyclic compound", "Cellular response to osmotic stress", "Cellular response to oxidised low density lipoprotein particle stimulus", "Cellular response to oxygen containing compound", "Cellular response to oxygen glucose deprivation", "Cellular response to oxygen levels", "Cellular response to oxygen radical", "Cellular response to parathyroid hormone stimulus", "Cellular response to peptide", "Cellular response to peptide hormone stimulus", "Cellular response to peptidoglycan", "Cellular response to ph", "Cellular response to potassium ion", "Cellular response to progesterone stimulus", "Cellular response to prostaglandin e stimulus", "Cellular response to prostaglandin stimulus", "Cellular response to purine containing compound", "Cellular response to radiation", "Cellular response to reactive nitrogen species", "Cellular response to reactive oxygen species", "Cellular response to retinoic acid", "Cellular response to salt", "Cellular response to salt stress", "Cellular response to sodium arsenite", "Cellular response to starvation", "Cellular response to steroid hormone stimulus", "Cellular response to sterol depletion", "Cellular response to stress", "Cellular response to testosterone stimulus", "Cellular response to thyroid hormone stimulus", "Cellular response to topologically incorrect protein", "Cellular response to toxic substance", "Cellular response to unfolded protein", "Cellular response to uv", "Cellular response to uv a", "Cellular response to uv c", "Cellular response to vascular endothelial growth factor stimulus", "Cellular response to virus", "Cellular response to vitamin", "Cellular response to vitamin d", "Cellular response to water stimulus", "Cellular response to x ray", "Cellular response to xenobiotic stimulus", "Cellular response to zinc ion", "Cellular senescence", "Cellular sodium ion homeostasis", "Cellular sphingolipid homeostasis", "Cellular transition metal ion homeostasis", "Cellular triglyceride homeostasis", "Cellular trivalent inorganic anion homeostasis", "Cenp a containing chromatin organization", "Central nervous system development", "Central nervous system maturation", "Central nervous system myelin formation", "Central nervous system myelin maintenance", "Central nervous system neuron axonogenesis", "Central nervous system neuron development", "Central nervous system neuron differentiation", "Central nervous system projection neuron axonogenesis", "Centriole assembly", "Centriole centriole cohesion", "Centriole elongation", "Centromere complex assembly", "Centromeric sister chromatid cohesion", "Centrosome duplication", "Centrosome separation", "Ceramide biosynthetic process", "Ceramide catabolic process", "Ceramide metabolic process", "Ceramide transport", "Cerebellar cortex development", "Cerebellar cortex formation", "Cerebellar cortex morphogenesis", "Cerebellar granular layer development", "Cerebellar granular layer morphogenesis", "Cerebellar purkinje cell layer development", "Cerebellar purkinje cell layer formation", "Cerebellar purkinje cell layer morphogenesis", "Cerebral cortex cell migration", "Cerebral cortex development", "Cerebral cortex neuron differentiation", "Cerebral cortex radially oriented cell migration", "Cerebral cortex regionalization", "Cerebral cortex tangential migration", "Cerebrospinal fluid circulation", "Cgmp mediated signaling", "Changes to dna methylation involved in embryo development", "Chaperone cofactor dependent protein refolding", "Chaperone mediated autophagy", "Chaperone mediated protein complex assembly", "Chaperone mediated protein folding", "Chemical homeostasis", "Chemical homeostasis within a tissue", "Chemical synaptic transmission postsynaptic", "Chemokine c c motif ligand 5 production", "Chemokine c x c motif ligand 12 signaling pathway", "Chemokine c x c motif ligand 2 production", "Chemokine production", "Chemosensory behavior", "Chloride transmembrane transport", "Chloride transport", "Cholesterol catabolic process", "Cholesterol efflux", "Cholesterol storage", "Choline metabolic process", "Chondroblast differentiation", "Chondrocyte development", "Chondrocyte development involved in endochondral bone morphogenesis", "Chondrocyte differentiation", "Chondrocyte differentiation involved in endochondral bone morphogenesis", "Chondrocyte proliferation", "Chondroitin sulfate biosynthetic process", "Chondroitin sulfate proteoglycan biosynthetic process", "Chondroitin sulfate proteoglycan metabolic process", "Chorio allantoic fusion", "Chorion development", "Chromatin assembly or disassembly", "Chromatin disassembly", "Chromatin organization", "Chromatin remodeling", "Chromatin remodeling at centromere", "Chromosome attachment to the nuclear envelope", "Chromosome condensation", "Chromosome localization", "Chromosome localization to nuclear envelope involved in homologous chromosome segregation", "Chromosome movement towards spindle pole", "Chromosome organization", "Chromosome organization involved in meiotic cell cycle", "Chromosome segregation", "Chromosome separation", "Cilium movement", "Cilium or flagellum dependent cell motility", "Cilium organization", "Circadian regulation of gene expression", "Circadian rhythm", "Circulatory system development", "Circulatory system process", "Citrate metabolic process", "Citrulline biosynthetic process", "Citrulline metabolic process", "Clathrin coat assembly", "Clathrin dependent endocytosis", "Cleavage furrow formation", "Cleavage involved in rrna processing", "Cobalamin metabolic process", "Cobalt ion transport", "Cochlea development", "Cochlea morphogenesis", "Coenzyme a biosynthetic process", "Coenzyme a metabolic process", "Cognition", "Cohesin loading", "Collagen biosynthetic process", "Collagen catabolic process", "Collagen fibril organization", "Collagen metabolic process", "Collateral sprouting", "Collateral sprouting in absence of injury", "Collecting duct development", "Columnar cuboidal epithelial cell development", "Columnar cuboidal epithelial cell differentiation", "Columnar cuboidal epithelial cell maturation", "Common partner smad protein phosphorylation", "Complement activation", "Complement dependent cytotoxicity", "Connective tissue development", "Connective tissue replacement", "Constitutive heterochromatin assembly", "Constitutive secretory pathway", "Convergent extension", "Convergent extension involved in axis elongation", "Convergent extension involved in gastrulation", "Convergent extension involved in organogenesis", "Cop9 signalosome assembly", "Copi coated vesicle budding", "Copii coated vesicle budding", "Copii coated vesicle cargo loading", "Copper ion homeostasis", "Copper ion transport", "Copulation", "Coronary vasculature development", "Corpus callosum development", "Corpus callosum morphogenesis", "Cortical actin cytoskeleton organization", "Cortical cytoskeleton organization", "Corticospinal tract morphogenesis", "Corticosteroid hormone secretion", "Corticosteroid receptor signaling pathway", "Corticotropin secretion", "Cortisol secretion", "Cotranslational protein targeting to membrane", "Cranial ganglion development", "Cranial nerve development", "Cranial skeletal system development", "Crd mediated mrna stabilization", "Cristae formation", "Cyclic gmp amp transmembrane import across plasma membrane", "Cyclic nucleotide catabolic process", "Cyclic nucleotide mediated signaling", "Cyclic nucleotide metabolic process", "Cyclooxygenase pathway", "Cysteine metabolic process", "Cytidine metabolic process", "Cytidine to uridine editing", "Cytochrome complex assembly", "Cytokine mediated signaling pathway", "Cytokine production", "Cytokine production involved in immune response", "Cytokine production involved in inflammatory response", "Cytokinesis", "Cytokinetic process", "Cytoplasm organization", "Cytoplasmic microtubule organization", "Cytoplasmic pattern recognition receptor signaling pathway", "Cytoplasmic pattern recognition receptor signaling pathway in response to virus", "Cytoplasmic sequestering of nf kappab", "Cytoplasmic sequestering of protein", "Cytoplasmic sequestering of transcription factor", "Cytoplasmic translation", "Cytoplasmic translational elongation", "Cytoplasmic translational initiation", "Cytoskeleton dependent cytokinesis", "Cytoskeleton dependent intracellular transport", "Cytoskeleton organization", "Cytosolic calcium ion transport", "Cytosolic transport", "D amino acid transport", "Damp metabolic process", "De novo amp biosynthetic process", "De novo protein folding", "De novo pyrimidine nucleobase biosynthetic process", "Deadenylation dependent decapping of nuclear transcribed mrna", "Decidualization", "Dedifferentiation", "Defense response", "Defense response to bacterium", "Defense response to fungus", "Defense response to gram negative bacterium", "Defense response to gram positive bacterium", "Defense response to other organism", "Defense response to symbiont", "Defense response to tumor cell", "Definitive erythrocyte differentiation", "Definitive hemopoiesis", "Delamination", "Demethylation", "Dendrite arborization", "Dendrite development", "Dendrite extension", "Dendrite morphogenesis", "Dendrite self avoidance", "Dendritic cell apoptotic process", "Dendritic cell chemotaxis", "Dendritic cell cytokine production", "Dendritic cell differentiation", "Dendritic cell migration", "Dendritic spine development", "Dendritic spine maintenance", "Dendritic spine morphogenesis", "Dendritic transport", "Dense core granule transport", "Dentate gyrus development", "Deoxyribonucleoside catabolic process", "Deoxyribonucleoside diphosphate metabolic process", "Deoxyribonucleoside metabolic process", "Deoxyribonucleoside monophosphate biosynthetic process", "Deoxyribonucleoside monophosphate catabolic process", "Deoxyribonucleoside monophosphate metabolic process", "Deoxyribonucleoside triphosphate biosynthetic process", "Deoxyribonucleoside triphosphate catabolic process", "Deoxyribonucleoside triphosphate metabolic process", "Deoxyribonucleotide biosynthetic process", "Deoxyribose phosphate catabolic process", "Deoxyribose phosphate metabolic process", "Dephosphorylation", "Dephosphorylation of rna polymerase ii c terminal domain", "Dermatan sulfate biosynthetic process", "Dermatan sulfate metabolic process", "Dermatan sulfate proteoglycan metabolic process", "Desmosome organization", "Detection of abiotic stimulus", "Detection of biotic stimulus", "Detection of calcium ion", "Detection of cell density", "Detection of external biotic stimulus", "Detection of light stimulus", "Detection of light stimulus involved in sensory perception", "Detection of mechanical stimulus", "Detection of molecule of bacterial origin", "Detection of muscle stretch", "Detection of other organism", "Detection of stimulus", "Detection of stimulus involved in sensory perception", "Detection of virus", "Detection of visible light", "Determination of adult lifespan", "Determination of dorsal ventral asymmetry", "Detoxification", "Detoxification of copper ion", "Detoxification of nitrogen compound", "Development of primary female sexual characteristics", "Development of primary sexual characteristics", "Development of secondary female sexual characteristics", "Development of secondary sexual characteristics", "Developmental cell growth", "Developmental growth", "Developmental growth involved in morphogenesis", "Developmental induction", "Developmental maturation", "Developmental pigmentation", "Developmental process involved in reproduction", "Diacylglycerol biosynthetic process", "Diacylglycerol metabolic process", "Diadenosine polyphosphate catabolic process", "Diadenosine polyphosphate metabolic process", "Diapedesis", "Diaphragm development", "Dicarboxylic acid biosynthetic process", "Dicarboxylic acid catabolic process", "Dicarboxylic acid metabolic process", "Dicarboxylic acid transport", "Diencephalon development", "Digestion", "Digestive system development", "Digestive system process", "Digestive tract morphogenesis", "Diol biosynthetic process", "Diol metabolic process", "Diphosphoinositol polyphosphate metabolic process", "Disaccharide metabolic process", "Diterpenoid biosynthetic process", "Divalent inorganic cation homeostasis", "Dna biosynthetic process", "Dna catabolic process", "Dna catabolic process endonucleolytic", "Dna catabolic process exonucleolytic", "Dna conformation change", "Dna cytosine deamination", "Dna damage induced protein phosphorylation", "Dna damage response signal transduction by p53 class mediator", "Dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest", "Dna damage response signal transduction resulting in transcription", "Dna dealkylation", "Dna dealkylation involved in dna repair", "Dna deamination", "Dna dependent dna replication", "Dna dependent dna replication maintenance of fidelity", "Dna double strand break processing", "Dna endoreduplication", "Dna geometric change", "Dna integration", "Dna integrity checkpoint signaling", "Dna ligation", "Dna ligation involved in dna repair", "Dna metabolic process", "Dna methylation", "Dna methylation dependent heterochromatin assembly", "Dna methylation involved in gamete generation", "Dna methylation on cytosine", "Dna methylation or demethylation", "Dna modification", "Dna packaging", "Dna protection", "Dna recombination", "Dna repair", "Dna replication", "Dna replication checkpoint signaling", "Dna replication dependent chromatin organization", "Dna replication independent chromatin organization", "Dna replication initiation", "Dna replication synthesis of rna primer", "Dna strand elongation", "Dna strand elongation involved in dna replication", "Dna synthesis involved in dna repair", "Dna templated transcription elongation", "Dna templated transcription initiation", "Dna templated transcription termination", "Dna topological change", "Dna unwinding involved in dna replication", "Dolichol metabolic process", "Dolichyl diphosphate biosynthetic process", "Dopamine biosynthetic process", "Dopamine metabolic process", "Dopamine receptor signaling pathway", "Dopamine transport", "Dopaminergic neuron differentiation", "Dorsal root ganglion development", "Dorsal ventral axis specification", "Dorsal ventral neural tube patterning", "Dorsal ventral pattern formation", "Dosage compensation", "Double strand break repair", "Double strand break repair involved in meiotic recombination", "Double strand break repair via break induced replication", "Double strand break repair via classical nonhomologous end joining", "Double strand break repair via nonhomologous end joining", "Double strand break repair via synthesis dependent strand annealing", "Dsrna processing", "Dtmp metabolic process", "Dttp metabolic process", "Dump metabolic process", "Ear development", "Ear morphogenesis", "Early endosome to golgi transport", "Eating behavior", "Ectoderm development", "Ectodermal placode development", "Ectopic germ cell programmed cell death", "Egg activation", "Electron transport chain", "Embryo development", "Embryo development ending in birth or egg hatching", "Embryo implantation", "Embryonic appendage morphogenesis", "Embryonic axis specification", "Embryonic body morphogenesis", "Embryonic brain development", "Embryonic camera type eye development", "Embryonic cleavage", "Embryonic cranial skeleton morphogenesis", "Embryonic digestive tract development", "Embryonic digestive tract morphogenesis", "Embryonic digit morphogenesis", "Embryonic forelimb morphogenesis", "Embryonic heart tube development", "Embryonic heart tube morphogenesis", "Embryonic hemopoiesis", "Embryonic hindlimb morphogenesis", "Embryonic morphogenesis", "Embryonic neurocranium morphogenesis", "Embryonic organ development", "Embryonic organ morphogenesis", "Embryonic pattern specification", "Embryonic placenta development", "Embryonic placenta morphogenesis", "Embryonic process involved in female pregnancy", "Embryonic skeletal joint development", "Embryonic skeletal joint morphogenesis", "Embryonic skeletal system development", "Embryonic skeletal system morphogenesis", "Embryonic viscerocranium morphogenesis", "Endocannabinoid signaling pathway", "Endocardium development", "Endochondral bone morphogenesis", "Endocrine hormone secretion", "Endocrine pancreas development", "Endocrine process", "Endocrine system development", "Endocytic recycling", "Endocytosis", "Endocytosis involved in viral entry into host cell", "Endoderm development", "Endoderm formation", "Endodermal cell differentiation", "Endodermal cell fate commitment", "Endomembrane system organization", "Endonucleolytic cleavage in 5 ets of tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage in its1 to separate ssu rrna from 5 8s rrna and lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage involved in rrna processing", "Endoplasmic reticulum calcium ion homeostasis", "Endoplasmic reticulum localization", "Endoplasmic reticulum mannose trimming", "Endoplasmic reticulum membrane organization", "Endoplasmic reticulum organization", "Endoplasmic reticulum plasma membrane tethering", "Endoplasmic reticulum to cytosol transport", "Endoplasmic reticulum to golgi vesicle mediated transport", "Endoplasmic reticulum tubular network organization", "Endoplasmic reticulum unfolded protein response", "Endosomal lumen acidification", "Endosomal transport", "Endosomal vesicle fusion", "Endosome organization", "Endosome to lysosome transport", "Endosome to lysosome transport via multivesicular body sorting pathway", "Endosome to plasma membrane protein transport", "Endosome transport via multivesicular body sorting pathway", "Endothelial cell activation", "Endothelial cell apoptotic process", "Endothelial cell chemotaxis", "Endothelial cell development", "Endothelial cell migration", "Endothelial cell morphogenesis", "Endothelial cell proliferation", "Endothelin receptor signaling pathway", "Endothelium development", "Energy derivation by oxidation of organic compounds", "Energy homeostasis", "Energy reserve metabolic process", "Engulfment of apoptotic cell", "Ensheathment of neurons", "Enteroendocrine cell differentiation", "Entrainment of circadian clock", "Entry into host", "Entry of bacterium into host cell", "Enucleate erythrocyte differentiation", "Enzyme directed rrna pseudouridine synthesis", "Enzyme linked receptor protein signaling pathway", "Eosinophil activation", "Eosinophil mediated immunity", "Ephrin receptor signaling pathway", "Epiboly", "Epidermal cell differentiation", "Epidermis development", "Epidermis morphogenesis", "Epigenetic maintenance of chromatin in transcription competent conformation", "Epithelial cell apoptotic process", "Epithelial cell cell adhesion", "Epithelial cell development", "Epithelial cell differentiation", "Epithelial cell differentiation involved in kidney development", "Epithelial cell differentiation involved in prostate gland development", "Epithelial cell maturation", "Epithelial cell morphogenesis", "Epithelial cell proliferation", "Epithelial cell proliferation involved in lung morphogenesis", "Epithelial cell proliferation involved in prostate gland development", "Epithelial fluid transport", "Epithelial structure maintenance", "Epithelial to mesenchymal transition", "Epithelial tube branching involved in lung morphogenesis", "Epithelial tube formation", "Epithelial tube morphogenesis", "Epithelium development", "Epoxide metabolic process", "Er associated misfolded protein catabolic process", "Er nucleus signaling pathway", "Er overload response", "Erad pathway", "Erbb signaling pathway", "Erbb2 signaling pathway", "Erk1 and erk2 cascade", "Error free translesion synthesis", "Error prone translesion synthesis", "Erythrocyte development", "Erythrocyte homeostasis", "Erythrocyte maturation", "Escrt complex disassembly", "Establishment of cell polarity", "Establishment of centrosome localization", "Establishment of endothelial barrier", "Establishment of endothelial intestinal barrier", "Establishment of epithelial cell apical basal polarity", "Establishment of epithelial cell polarity", "Establishment of golgi localization", "Establishment of lymphocyte polarity", "Establishment of meiotic spindle localization", "Establishment of mitochondrion localization", "Establishment of mitotic spindle localization", "Establishment of organelle localization", "Establishment of pigment granule localization", "Establishment of planar polarity involved in neural tube closure", "Establishment of planar polarity of embryonic epithelium", "Establishment of protein localization", "Establishment of protein localization to chromatin", "Establishment of protein localization to chromosome", "Establishment of protein localization to endoplasmic reticulum", "Establishment of protein localization to membrane", "Establishment of protein localization to mitochondrial membrane", "Establishment of protein localization to organelle", "Establishment of protein localization to plasma membrane", "Establishment of protein localization to telomere", "Establishment of protein localization to vacuole", "Establishment of rna localization", "Establishment of sister chromatid cohesion", "Establishment of spindle orientation", "Establishment of tissue polarity", "Establishment or maintenance of bipolar cell polarity", "Establishment or maintenance of cell polarity", "Establishment or maintenance of cytoskeleton polarity", "Establishment or maintenance of monopolar cell polarity", "Establishment or maintenance of transmembrane electrochemical gradient", "Estrogen biosynthetic process", "Estrogen metabolic process", "Estrous cycle", "Ethanol catabolic process", "Ethanol metabolic process", "Ethanol oxidation", "Ethanolamine containing compound metabolic process", "Ether biosynthetic process", "Ether metabolic process", "Excitatory synapse assembly", "Excretion", "Execution phase of apoptosis", "Exit from mitosis", "Exocrine pancreas development", "Exocrine system development", "Exocyst localization", "Exocytic process", "Exocytosis", "Exonucleolytic catabolism of deadenylated mrna", "Exploration behavior", "Export across plasma membrane", "Export from cell", "External encapsulating structure organization", "Extracellular exosome assembly", "Extracellular matrix assembly", "Extracellular matrix constituent secretion", "Extracellular matrix disassembly", "Extracellular regulation of signal transduction", "Extracellular transport", "Extracellular vesicle biogenesis", "Extraembryonic membrane development", "Extrinsic apoptotic signaling pathway", "Extrinsic apoptotic signaling pathway via death domain receptors", "Eye morphogenesis", "Eye photoreceptor cell development", "Eye photoreceptor cell differentiation", "Eye pigmentation", "Eyelid development in camera type eye", "Face development", "Facultative heterochromatin assembly", "Farnesyl diphosphate metabolic process", "Fas signaling pathway", "Fat cell differentiation", "Fat cell proliferation", "Fat pad development", "Fat soluble vitamin biosynthetic process", "Fat soluble vitamin metabolic process", "Fatty acid alpha oxidation", "Fatty acid beta oxidation", "Fatty acid beta oxidation using acyl coa dehydrogenase", "Fatty acid beta oxidation using acyl coa oxidase", "Fatty acid biosynthetic process", "Fatty acid catabolic process", "Fatty acid derivative biosynthetic process", "Fatty acid derivative catabolic process", "Fatty acid derivative metabolic process", "Fatty acid elongation", "Fatty acid homeostasis", "Fatty acid metabolic process", "Fatty acid omega oxidation", "Fatty acid transmembrane transport", "Fatty acid transport", "Fatty acyl coa biosynthetic process", "Fatty acyl coa catabolic process", "Fatty acyl coa metabolic process", "Fc epsilon receptor signaling pathway", "Fc gamma receptor signaling pathway", "Fc receptor mediated stimulatory signaling pathway", "Fc receptor signaling pathway", "Fear response", "Feeding behavior", "Female gamete generation", "Female genitalia development", "Female meiosis chromosome segregation", "Female meiosis i", "Female meiotic nuclear division", "Female sex differentiation", "Fermentation", "Fertilization", "Fibroblast activation", "Fibroblast apoptotic process", "Fibroblast growth factor production", "Fibroblast growth factor receptor signaling pathway", "Fibroblast migration", "Fibroblast proliferation", "Filopodium assembly", "Flavin containing compound metabolic process", "Flavonoid metabolic process", "Fluid transport", "Foam cell differentiation", "Focal adhesion assembly", "Folate import across plasma membrane", "Folate transmembrane transport", "Folic acid containing compound biosynthetic process", "Folic acid containing compound catabolic process", "Folic acid containing compound metabolic process", "Folic acid metabolic process", "Folic acid transport", "Forebrain cell migration", "Forebrain development", "Forebrain generation of neurons", "Forebrain morphogenesis", "Forebrain neuron development", "Forebrain neuron differentiation", "Forebrain radial glial cell differentiation", "Forebrain regionalization", "Foregut morphogenesis", "Forelimb morphogenesis", "Formate metabolic process", "Formation of extrachromosomal circular dna", "Formation of primary germ layer", "Formation of translation preinitiation complex", "Free ubiquitin chain polymerization", "Fructose 1 6 bisphosphate metabolic process", "Fructose 2 6 bisphosphate metabolic process", "Fructose 6 phosphate metabolic process", "Fructose metabolic process", "Fucose metabolic process", "Fucosylation", "Fungiform papilla development", "Fungiform papilla morphogenesis", "G protein coupled acetylcholine receptor signaling pathway", "G protein coupled opioid receptor signaling pathway", "G protein coupled purinergic receptor signaling pathway", "G protein coupled receptor internalization", "G protein coupled receptor signaling pathway", "G protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger", "G protein coupled receptor signaling pathway involved in heart process", "G quadruplex dna unwinding", "G0 to g1 transition", "G1 to g0 transition", "G2 mi transition of meiotic cell cycle", "Galactose catabolic process", "Galactose metabolic process", "Gamete generation", "Gamma aminobutyric acid metabolic process", "Gamma aminobutyric acid signaling pathway", "Gamma aminobutyric acid transport", "Ganglion development", "Ganglioside catabolic process", "Ganglioside metabolic process", "Gap junction assembly", "Gap junction mediated intercellular transport", "Gas homeostasis", "Gastrulation", "Gastrulation with mouth forming second", "Gdp mannose metabolic process", "Gdp metabolic process", "Gene silencing by rna", "Generation of precursor metabolites and energy", "Genitalia development", "Genitalia morphogenesis", "Genomic imprinting", "Germ cell development", "Germ cell migration", "Germ cell proliferation", "Germinal center b cell differentiation", "Germinal center formation", "Gland development", "Gland morphogenesis", "Glandular epithelial cell development", "Glandular epithelial cell differentiation", "Glial cell apoptotic process", "Glial cell development", "Glial cell differentiation", "Glial cell fate commitment", "Glial cell migration", "Glial cell proliferation", "Gliogenesis", "Glomerular basement membrane development", "Glomerular epithelial cell development", "Glomerular epithelial cell differentiation", "Glomerular epithelium development", "Glomerular visceral epithelial cell migration", "Glomerulus development", "Glucan biosynthetic process", "Glucocorticoid biosynthetic process", "Glucocorticoid metabolic process", "Glucocorticoid secretion", "Glucosamine containing compound catabolic process", "Glucosamine containing compound metabolic process", "Glucose 6 phosphate metabolic process", "Glucose catabolic process", "Glucose import", "Glucose import in response to insulin stimulus", "Glucose metabolic process", "Glucosylceramide metabolic process", "Glutamate biosynthetic process", "Glutamate catabolic process", "Glutamate homeostasis", "Glutamate metabolic process", "Glutamate receptor signaling pathway", "Glutamate reuptake", "Glutamate secretion", "Glutamate secretion neurotransmission", "Glutamine family amino acid biosynthetic process", "Glutamine family amino acid catabolic process", "Glutamine family amino acid metabolic process", "Glutamine metabolic process", "Glutamine transport", "Glutathione catabolic process", "Glutathione metabolic process", "Glycerol 3 phosphate metabolic process", "Glycerol ether metabolic process", "Glycerolipid biosynthetic process", "Glycerolipid catabolic process", "Glycerolipid metabolic process", "Glycerophospholipid biosynthetic process", "Glycerophospholipid catabolic process", "Glycerophospholipid metabolic process", "Glycine biosynthetic process", "Glycine metabolic process", "Glycolipid biosynthetic process", "Glycolipid catabolic process", "Glycolipid transport", "Glycolytic fermentation", "Glycolytic process through fructose 6 phosphate", "Glycoprotein biosynthetic process", "Glycoprotein catabolic process", "Glycoprotein metabolic process", "Glycosaminoglycan catabolic process", "Glycoside catabolic process", "Glycoside metabolic process", "Glycosphingolipid biosynthetic process", "Glycosphingolipid metabolic process", "Glycosyl compound biosynthetic process", "Glycosyl compound catabolic process", "Glycosyl compound metabolic process", "Glycosylation", "Glycosylceramide biosynthetic process", "Glycosylceramide catabolic process", "Glycosylceramide metabolic process", "Glyoxylate metabolic process", "Gmp biosynthetic process", "Gmp metabolic process", "Gmp salvage", "Golgi disassembly", "Golgi localization", "Golgi organization", "Golgi ribbon formation", "Golgi to endosome transport", "Golgi to lysosome transport", "Golgi to plasma membrane protein transport", "Golgi to plasma membrane transport", "Golgi to vacuole transport", "Golgi vesicle budding", "Golgi vesicle transport", "Gonadotropin secretion", "Gpi anchor metabolic process", "Granulocyte activation", "Granulocyte chemotaxis", "Granulocyte differentiation", "Granulocyte migration", "Granzyme mediated programmed cell death signaling pathway", "Grooming behavior", "Growth", "Growth hormone receptor signaling pathway via jak stat", "Growth hormone secretion", "Growth plate cartilage chondrocyte differentiation", "Growth plate cartilage development", "Gtp biosynthetic process", "Gtp metabolic process", "Guanine metabolic process", "Guanine nucleotide transmembrane transport", "Guanine nucleotide transport", "Hair cell differentiation", "Hair cycle phase", "Hair follicle maturation", "Hair follicle placode formation", "Head development", "Head morphogenesis", "Heart development", "Heart formation", "Heart growth", "Heart morphogenesis", "Heart process", "Heart trabecula formation", "Heart trabecula morphogenesis", "Heart valve development", "Heart valve morphogenesis", "Heat acclimation", "Hematopoietic progenitor cell differentiation", "Hematopoietic stem cell differentiation", "Hematopoietic stem cell homeostasis", "Hematopoietic stem cell proliferation", "Heme transport", "Hemidesmosome assembly", "Hemoglobin biosynthetic process", "Hemoglobin metabolic process", "Hemostasis", "Heparan sulfate proteoglycan biosynthetic process", "Heparan sulfate proteoglycan biosynthetic process enzymatic modification", "Heparan sulfate proteoglycan biosynthetic process polysaccharide chain biosynthetic process", "Heparan sulfate proteoglycan metabolic process", "Hepatic stellate cell activation", "Hepaticobiliary system development", "Hepatocyte apoptotic process", "Hepatocyte differentiation", "Hepatocyte growth factor receptor signaling pathway", "Hepoxilin metabolic process", "Heterochromatin organization", "Heterophilic cell cell adhesion via plasma membrane cell adhesion molecules", "Heterotypic cell cell adhesion", "High density lipoprotein particle assembly", "High density lipoprotein particle clearance", "High density lipoprotein particle remodeling", "Hindbrain development", "Hindbrain maturation", "Hindbrain morphogenesis", "Hindbrain radial glia guided cell migration", "Hindgut development", "Hindlimb morphogenesis", "Hippo signaling", "Hippocampus development", "His purkinje system development", "Histamine production involved in inflammatory response", "Histamine secretion", "Histamine transport", "Histidine metabolic process", "Histone arginine methylation", "Histone deacetylation", "Histone dephosphorylation", "Histone deubiquitination", "Histone exchange", "Histone h2a acetylation", "Histone h2a k63 linked ubiquitination", "Histone h2a monoubiquitination", "Histone h2a phosphorylation", "Histone h2a ubiquitination", "Histone h2b ubiquitination", "Histone h3 acetylation", "Histone h3 deacetylation", "Histone h3 k14 acetylation", "Histone h3 k27 demethylation", "Histone h3 k27 methylation", "Histone h3 k27 trimethylation", "Histone h3 k36 demethylation", "Histone h3 k36 methylation", "Histone h3 k36 trimethylation", "Histone h3 k4 demethylation", "Histone h3 k4 demethylation trimethyl h3 k4 specific", "Histone h3 k4 dimethylation", "Histone h3 k4 methylation", "Histone h3 k4 monomethylation", "Histone h3 k4 trimethylation", "Histone h3 k9 acetylation", "Histone h3 k9 demethylation", "Histone h3 k9 dimethylation", "Histone h3 k9 methylation", "Histone h3 k9 modification", "Histone h3 k9 trimethylation", "Histone h4 acetylation", "Histone h4 deacetylation", "Histone h4 k12 acetylation", "Histone h4 k16 acetylation", "Histone h4 k20 methylation", "Histone h4 k20 trimethylation", "Histone h4 k5 acetylation", "Histone h4 r3 methylation", "Histone lysine demethylation", "Histone methylation", "Histone modification", "Histone monoubiquitination", "Histone mrna catabolic process", "Histone mrna metabolic process", "Histone phosphorylation", "Histone serine phosphorylation", "Histone threonine phosphorylation", "Histone ubiquitination", "Homeostasis of number of cells", "Homeostasis of number of cells within a tissue", "Homeostatic process", "Homocysteine metabolic process", "Homologous chromosome pairing at meiosis", "Homologous chromosome segregation", "Homologous recombination", "Homophilic cell adhesion via plasma membrane adhesion molecules", "Homotypic cell cell adhesion", "Hormone biosynthetic process", "Hormone catabolic process", "Hormone mediated signaling pathway", "Hormone metabolic process", "Hormone transport", "Humoral immune response", "Humoral immune response mediated by circulating immunoglobulin", "Hyaluronan biosynthetic process", "Hyaluronan metabolic process", "Hydrogen peroxide biosynthetic process", "Hydrogen peroxide catabolic process", "Hydrogen peroxide metabolic process", "Hydrogen sulfide biosynthetic process", "Hydrogen sulfide metabolic process", "Hyperosmotic response", "Hyperosmotic salinity response", "Hypothalamus cell differentiation", "Hypothalamus development", "Hypotonic response", "Hypoxia inducible factor 1alpha signaling pathway", "I kappab kinase nf kappab signaling", "I kappab phosphorylation", "Icosanoid biosynthetic process", "Icosanoid metabolic process", "Icosanoid transport", "Immune complex clearance", "Immune effector process", "Immune response", "Immune response regulating cell surface receptor signaling pathway", "Immune response regulating signaling pathway", "Immune response to tumor cell", "Immune system development", "Immunoglobulin production", "Immunoglobulin production involved in immunoglobulin mediated immune response", "Immunoglobulin v d j recombination", "Immunological synapse formation", "Imp biosynthetic process", "Imp catabolic process", "Imp metabolic process", "Imp salvage", "Import across plasma membrane", "Import into cell", "Import into nucleus", "In utero embryonic development", "Inclusion body assembly", "Indolalkylamine metabolic process", "Indole containing compound biosynthetic process", "Indole containing compound metabolic process", "Inflammasome complex assembly", "Inflammatory cell apoptotic process", "Inflammatory response", "Inflammatory response to antigenic stimulus", "Inflammatory response to wounding", "Innate immune response", "Innate immune response activating signal transduction", "Innate immune response in mucosa", "Inner cell mass cell differentiation", "Inner cell mass cell proliferation", "Inner dynein arm assembly", "Inner ear auditory receptor cell differentiation", "Inner ear morphogenesis", "Inner ear receptor cell development", "Inner ear receptor cell stereocilium organization", "Inner mitochondrial membrane organization", "Innervation", "Inorganic anion transmembrane transport", "Inorganic anion transport", "Inorganic ion import across plasma membrane", "Inorganic ion transmembrane transport", "Inosine metabolic process", "Inositol lipid mediated signaling", "Inositol metabolic process", "Inositol phosphate catabolic process", "Inositol phosphate mediated signaling", "Inositol phosphate metabolic process", "Insulin like growth factor receptor signaling pathway", "Insulin metabolic process", "Insulin processing", "Insulin receptor signaling pathway", "Insulin secretion", "Insulin secretion involved in cellular response to glucose stimulus", "Integrated stress response signaling", "Integrin activation", "Integrin mediated signaling pathway", "Intercellular transport", "Interferon alpha production", "Interferon beta production", "Interferon gamma mediated signaling pathway", "Interferon gamma production", "Interleukin 1 alpha production", "Interleukin 1 mediated signaling pathway", "Interleukin 1 production", "Interleukin 10 production", "Interleukin 12 production", "Interleukin 13 production", "Interleukin 17 production", "Interleukin 18 mediated signaling pathway", "Interleukin 18 production", "Interleukin 2 production", "Interleukin 23 production", "Interleukin 27 mediated signaling pathway", "Interleukin 6 mediated signaling pathway", "Interleukin 6 production", "Interleukin 8 production", "Intermediate filament based process", "Intermediate filament bundle assembly", "Intermediate filament organization", "Intermembrane lipid transfer", "Interstrand cross link repair", "Intestinal absorption", "Intestinal epithelial cell development", "Intestinal epithelial cell differentiation", "Intestinal hexose absorption", "Intestinal lipid absorption", "Intra golgi vesicle mediated transport", "Intracellular distribution of mitochondria", "Intracellular estrogen receptor signaling pathway", "Intracellular lipid transport", "Intracellular mrna localization", "Intracellular protein transmembrane transport", "Intracellular protein transport", "Intracellular receptor signaling pathway", "Intracellular sterol transport", "Intracellular transport", "Intracellular transport of virus", "Intraciliary retrograde transport", "Intraciliary transport", "Intraciliary transport involved in cilium assembly", "Intrinsic apoptotic signaling pathway", "Intrinsic apoptotic signaling pathway by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to dna damage", "Intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress", "Intrinsic apoptotic signaling pathway in response to hydrogen peroxide", "Intrinsic apoptotic signaling pathway in response to hypoxia", "Intrinsic apoptotic signaling pathway in response to osmotic stress", "Intrinsic apoptotic signaling pathway in response to oxidative stress", "Ion homeostasis", "Ion transmembrane transport", "Ion transport", "Ire1 mediated unfolded protein response", "Ires dependent viral translational initiation", "Iron coordination entity transport", "Iron import into cell", "Iron ion homeostasis", "Iron ion import across plasma membrane", "Iron ion transmembrane transport", "Iron ion transport", "Iron sulfur cluster assembly", "Isocitrate metabolic process", "Isoleucine metabolic process", "Isopentenyl diphosphate biosynthetic process", "Isoprenoid biosynthetic process", "Isoprenoid metabolic process", "Isotype switching to iga isotypes", "Isotype switching to igg isotypes", "Jnk cascade", "Keratan sulfate metabolic process", "Keratinization", "Keratinocyte development", "Keratinocyte differentiation", "Keratinocyte migration", "Keratinocyte proliferation", "Ketone biosynthetic process", "Ketone body biosynthetic process", "Ketone body metabolic process", "Ketone catabolic process", "Kidney epithelium development", "Kidney mesenchyme development", "Kidney morphogenesis", "Killing by host of symbiont cells", "Killing of cells of another organism", "Kinetochore assembly", "Kinetochore organization", "Kynurenine metabolic process", "L alanine transport", "L alpha amino acid transmembrane transport", "L amino acid transport", "L ascorbic acid metabolic process", "L aspartate transmembrane transport", "L glutamate import across plasma membrane", "L glutamate transmembrane transport", "L kynurenine metabolic process", "L methionine salvage from methylthioadenosine", "L phenylalanine metabolic process", "L proline biosynthetic process", "L serine biosynthetic process", "L serine catabolic process", "L serine metabolic process", "L serine transport", "Labyrinthine layer blood vessel development", "Labyrinthine layer development", "Labyrinthine layer morphogenesis", "Lactate metabolic process", "Lactate transmembrane transport", "Lactation", "Lamellipodium assembly", "Lamellipodium morphogenesis", "Lamellipodium organization", "Late endosome to golgi transport", "Late endosome to lysosome transport", "Late endosome to vacuole transport", "Late endosome to vacuole transport via multivesicular body sorting pathway", "Late nucleophagy", "Lateral mesoderm development", "Lateral ventricle development", "Layer formation in cerebral cortex", "Learned vocalization behavior or vocal learning", "Learning", "Left right axis specification", "Left right pattern formation", "Lens development in camera type eye", "Lens fiber cell development", "Lens fiber cell differentiation", "Lens morphogenesis in camera type eye", "Leptin mediated signaling pathway", "Leucine catabolic process", "Leucine import across plasma membrane", "Leucine metabolic process", "Leucine transport", "Leukocyte adhesion to vascular endothelial cell", "Leukocyte aggregation", "Leukocyte apoptotic process", "Leukocyte cell cell adhesion", "Leukocyte chemotaxis", "Leukocyte degranulation", "Leukocyte differentiation", "Leukocyte homeostasis", "Leukocyte mediated cytotoxicity", "Leukocyte mediated immunity", "Leukocyte migration", "Leukocyte proliferation", "Leukocyte tethering or rolling", "Leukotriene b4 metabolic process", "Leukotriene biosynthetic process", "Leukotriene d4 metabolic process", "Leukotriene metabolic process", "Leukotriene transport", "Leydig cell differentiation", "Limb joint morphogenesis", "Limbic system development", "Linoleic acid metabolic process", "Lipid biosynthetic process", "Lipid catabolic process", "Lipid digestion", "Lipid droplet formation", "Lipid droplet organization", "Lipid export from cell", "Lipid glycosylation", "Lipid homeostasis", "Lipid import into cell", "Lipid localization", "Lipid metabolic process", "Lipid modification", "Lipid oxidation", "Lipid phosphorylation", "Lipid storage", "Lipid translocation", "Lipid transport across blood brain barrier", "Lipophagy", "Lipopolysaccharide mediated signaling pathway", "Lipoprotein biosynthetic process", "Lipoprotein catabolic process", "Lipoprotein localization", "Lipoprotein metabolic process", "Liposaccharide metabolic process", "Lipoxin metabolic process", "Liver morphogenesis", "Liver regeneration", "Localization within membrane", "Locomotion", "Locomotion involved in locomotory behavior", "Locomotor rhythm", "Locomotory behavior", "Locomotory exploration behavior", "Long chain fatty acid biosynthetic process", "Long chain fatty acid import across plasma membrane", "Long chain fatty acid metabolic process", "Long chain fatty acid transport", "Long chain fatty acyl coa biosynthetic process", "Long chain fatty acyl coa metabolic process", "Long term memory", "Long term synaptic depression", "Long term synaptic potentiation", "Low density lipoprotein particle clearance", "Low density lipoprotein receptor particle metabolic process", "Lung alveolus development", "Lung associated mesenchyme development", "Lung cell differentiation", "Lung epithelium development", "Lung morphogenesis", "Lung saccule development", "Lung secretory cell differentiation", "Luteinization", "Luteinizing hormone secretion", "Luteolysis", "Lymphocyte activation", "Lymphocyte activation involved in immune response", "Lymphocyte aggregation", "Lymphocyte anergy", "Lymphocyte apoptotic process", "Lymphocyte chemotaxis", "Lymphocyte costimulation", "Lymphocyte homeostasis", "Lymphocyte mediated immunity", "Lymphocyte migration", "Lymphocyte migration into lymphoid organs", "Lymphoid progenitor cell differentiation", "Lysine catabolic process", "Lysine metabolic process", "Lysosomal lumen acidification", "Lysosomal membrane organization", "Lysosomal microautophagy", "Lysosomal protein catabolic process", "Lysosomal transport", "Lytic vacuole organization", "Macroautophagy", "Macromolecule catabolic process", "Macromolecule deacylation", "Macromolecule depalmitoylation", "Macrophage activation", "Macrophage apoptotic process", "Macrophage chemotaxis", "Macrophage cytokine production", "Macrophage differentiation", "Macrophage migration", "Macrophage proliferation", "Macropinocytosis", "Magnesium ion homeostasis", "Magnesium ion transport", "Maintenance of apical basal cell polarity", "Maintenance of blood brain barrier", "Maintenance of cell number", "Maintenance of cell polarity", "Maintenance of centrosome location", "Maintenance of dna methylation", "Maintenance of dna repeat elements", "Maintenance of gastrointestinal epithelium", "Maintenance of lens transparency", "Maintenance of location", "Maintenance of location in cell", "Maintenance of organelle location", "Maintenance of postsynaptic specialization structure", "Maintenance of presynaptic active zone structure", "Maintenance of protein localization in endoplasmic reticulum", "Maintenance of protein localization in organelle", "Maintenance of protein location", "Maintenance of protein location in cell", "Maintenance of protein location in mitochondrion", "Maintenance of protein location in nucleus", "Maintenance of sister chromatid cohesion", "Maintenance of synapse structure", "Malate metabolic process", "Male gamete generation", "Male genitalia development", "Male mating behavior", "Male meiosis i", "Male meiotic nuclear division", "Male sex determination", "Male sex differentiation", "Malonyl coa metabolic process", "Mammalian oogenesis stage", "Mammary gland alveolus development", "Mammary gland branching involved in pregnancy", "Mammary gland development", "Mammary gland duct morphogenesis", "Mammary gland epithelial cell differentiation", "Mammary gland epithelial cell proliferation", "Mammary gland epithelium development", "Mammary gland involution", "Mammary gland morphogenesis", "Manganese ion transmembrane transport", "Manganese ion transport", "Mannose metabolic process", "Mannosylation", "Mapk cascade", "Mast cell activation", "Mast cell activation involved in immune response", "Mast cell cytokine production", "Maternal placenta development", "Maternal process involved in female pregnancy", "Mating", "Mating behavior", "Maturation of 5 8s rrna", "Maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of lsu rrna", "Maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of ssu rrna", "Maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Mature b cell differentiation", "Mature ribosome assembly", "Mda 5 signaling pathway", "Mechanoreceptor differentiation", "Mechanosensory behavior", "Medium chain fatty acid biosynthetic process", "Medium chain fatty acid catabolic process", "Medium chain fatty acid metabolic process", "Medium chain fatty acyl coa metabolic process", "Megakaryocyte development", "Megakaryocyte differentiation", "Meiosis i cell cycle process", "Meiosis ii cell cycle process", "Meiotic cell cycle", "Meiotic cell cycle checkpoint signaling", "Meiotic cell cycle phase transition", "Meiotic cell cycle process", "Meiotic chromosome condensation", "Meiotic chromosome segregation", "Meiotic chromosome separation", "Meiotic cytokinesis", "Meiotic dna double strand break formation", "Meiotic sister chromatid cohesion centromeric", "Meiotic spindle assembly", "Meiotic spindle organization", "Melanocyte differentiation", "Membrane biogenesis", "Membrane depolarization", "Membrane depolarization during action potential", "Membrane depolarization during cardiac muscle cell action potential", "Membrane disassembly", "Membrane docking", "Membrane fission", "Membrane fusion", "Membrane hyperpolarization", "Membrane invagination", "Membrane lipid biosynthetic process", "Membrane lipid catabolic process", "Membrane lipid metabolic process", "Membrane organization", "Membrane protein ectodomain proteolysis", "Membrane protein intracellular domain proteolysis", "Membrane protein proteolysis", "Membrane raft assembly", "Membrane raft localization", "Membrane raft organization", "Membrane repolarization", "Membrane repolarization during action potential", "Membrane repolarization during atrial cardiac muscle cell action potential", "Membrane repolarization during cardiac muscle cell action potential", "Membrane to membrane docking", "Membranous septum morphogenesis", "Memory", "Mesangial cell development", "Mesangial cell differentiation", "Mesenchymal cell development", "Mesenchymal cell differentiation", "Mesenchymal cell differentiation involved in kidney development", "Mesenchymal cell proliferation", "Mesenchymal cell proliferation involved in lung development", "Mesenchymal stem cell differentiation", "Mesenchymal stem cell proliferation", "Mesenchymal to epithelial transition", "Mesenchymal to epithelial transition involved in metanephros morphogenesis", "Mesenchyme development", "Mesenchyme morphogenesis", "Mesoderm development", "Mesoderm morphogenesis", "Mesodermal cell differentiation", "Mesonephric duct development", "Mesonephric tubule formation", "Mesonephric tubule morphogenesis", "Mesonephros development", "Metal ion export", "Metal ion homeostasis", "Metal ion transport", "Metanephric collecting duct development", "Metanephric epithelium development", "Metanephric glomerulus development", "Metanephric glomerulus vasculature development", "Metanephric mesenchymal cell differentiation", "Metanephric mesenchyme development", "Metanephric nephron development", "Metanephric nephron morphogenesis", "Metanephric nephron tubule epithelial cell differentiation", "Metanephric part of ureteric bud development", "Metanephric renal vesicle morphogenesis", "Metanephric tubule development", "Metanephros development", "Metanephros morphogenesis", "Metaphase anaphase transition of cell cycle", "Metaphase plate congression", "Metencephalon development", "Methionine biosynthetic process", "Methionine metabolic process", "Methylation", "Methylglyoxal metabolic process", "Methylguanosine cap decapping", "Mhc class i biosynthetic process", "Mhc class ii biosynthetic process", "Microglia differentiation", "Microglial cell activation", "Microglial cell proliferation", "Microtubule anchoring", "Microtubule anchoring at centrosome", "Microtubule anchoring at microtubule organizing center", "Microtubule based movement", "Microtubule based process", "Microtubule based transport", "Microtubule bundle formation", "Microtubule cytoskeleton organization", "Microtubule cytoskeleton organization involved in mitosis", "Microtubule depolymerization", "Microtubule nucleation", "Microtubule organizing center localization", "Microtubule organizing center organization", "Microtubule polymerization", "Microtubule polymerization or depolymerization", "Microtubule severing", "Microvillus assembly", "Microvillus organization", "Midbody abscission", "Midbrain development", "Midbrain dopaminergic neuron differentiation", "Middle ear morphogenesis", "Midgut development", "Minus end directed organelle transport along microtubule", "Mirna catabolic process", "Mirna loading onto risc involved in gene silencing by mirna", "Mirna metabolic process", "Mismatch repair", "Mitochondrial acetyl coa biosynthetic process from pyruvate", "Mitochondrial adp transmembrane transport", "Mitochondrial atp synthesis coupled proton transport", "Mitochondrial calcium ion homeostasis", "Mitochondrial calcium ion transmembrane transport", "Mitochondrial cytochrome c oxidase assembly", "Mitochondrial depolarization", "Mitochondrial dna metabolic process", "Mitochondrial dna repair", "Mitochondrial dna replication", "Mitochondrial electron transport cytochrome c to oxygen", "Mitochondrial electron transport nadh to ubiquinone", "Mitochondrial electron transport ubiquinol to cytochrome c", "Mitochondrial fission", "Mitochondrial fragmentation involved in apoptotic process", "Mitochondrial fusion", "Mitochondrial gene expression", "Mitochondrial genome maintenance", "Mitochondrial membrane organization", "Mitochondrial outer membrane permeabilization", "Mitochondrial outer membrane permeabilization involved in programmed cell death", "Mitochondrial protein catabolic process", "Mitochondrial protein processing", "Mitochondrial proton transporting atp synthase complex assembly", "Mitochondrial respirasome assembly", "Mitochondrial respiratory chain complex assembly", "Mitochondrial ribosome assembly", "Mitochondrial rna 3 end processing", "Mitochondrial rna catabolic process", "Mitochondrial rna metabolic process", "Mitochondrial rna modification", "Mitochondrial rna processing", "Mitochondrial transcription", "Mitochondrial translation", "Mitochondrial translational elongation", "Mitochondrial transmembrane transport", "Mitochondrial transport", "Mitochondrial trna processing", "Mitochondrion distribution", "Mitochondrion endoplasmic reticulum membrane tethering", "Mitochondrion localization", "Mitochondrion morphogenesis", "Mitochondrion organization", "Mitophagy", "Mitotic cell cycle", "Mitotic cell cycle checkpoint signaling", "Mitotic cell cycle phase transition", "Mitotic cell cycle process", "Mitotic chromosome condensation", "Mitotic cytokinesis", "Mitotic cytokinetic process", "Mitotic dna integrity checkpoint signaling", "Mitotic dna replication", "Mitotic dna replication checkpoint signaling", "Mitotic g1 s transition checkpoint signaling", "Mitotic g2 dna damage checkpoint signaling", "Mitotic g2 m transition checkpoint", "Mitotic intra s dna damage checkpoint signaling", "Mitotic metaphase plate congression", "Mitotic nuclear division", "Mitotic nuclear membrane disassembly", "Mitotic nuclear membrane organization", "Mitotic recombination", "Mitotic sister chromatid cohesion", "Mitotic sister chromatid segregation", "Mitotic spindle assembly", "Mitotic spindle midzone assembly", "Mitotic spindle organization", "Modification dependent macromolecule catabolic process", "Modification of postsynaptic actin cytoskeleton", "Modification of postsynaptic structure", "Modification of synaptic structure", "Modified amino acid transport", "Modulation by host of symbiont catalytic activity", "Modulation by host of symbiont process", "Modulation by host of viral genome replication", "Modulation by host of viral process", "Modulation of age related behavioral decline", "Modulation of excitatory postsynaptic potential", "Molting cycle", "Monoacylglycerol catabolic process", "Monoacylglycerol metabolic process", "Monoamine transport", "Monocarboxylic acid biosynthetic process", "Monocarboxylic acid catabolic process", "Monocarboxylic acid metabolic process", "Monocarboxylic acid transport", "Monocyte chemotactic protein 1 production", "Monocyte chemotaxis", "Monocyte differentiation", "Monocyte extravasation", "Mononuclear cell differentiation", "Mononuclear cell migration", "Monosaccharide biosynthetic process", "Monosaccharide catabolic process", "Monosaccharide metabolic process", "Monoubiquitinated protein deubiquitination", "Monovalent inorganic anion homeostasis", "Monovalent inorganic cation homeostasis", "Morphogenesis of a branching structure", "Morphogenesis of a polarized epithelium", "Morphogenesis of an endothelium", "Morphogenesis of an epithelial bud", "Morphogenesis of an epithelial fold", "Morphogenesis of an epithelial sheet", "Morphogenesis of an epithelium", "Morphogenesis of embryonic epithelium", "Motor behavior", "Motor learning", "Motor neuron apoptotic process", "Motor neuron axon guidance", "Mrna 3 end processing", "Mrna 3 end processing by stem loop binding and cleavage", "Mrna 3 splice site recognition", "Mrna 5 splice site recognition", "Mrna alternative polyadenylation", "Mrna catabolic process", "Mrna cis splicing via spliceosome", "Mrna cleavage", "Mrna cleavage involved in mrna processing", "Mrna destabilization mediated gene silencing", "Mrna export from nucleus", "Mrna metabolic process", "Mrna methylation", "Mrna modification", "Mrna processing", "Mrna pseudouridine synthesis", "Mrna splice site selection", "Mrna transcription", "Mrna transport", "Mucopolysaccharide metabolic process", "Mucosa associated lymphoid tissue development", "Mucus secretion", "Multi multicellular organism process", "Multi organism reproductive process", "Multicellular organism aging", "Multicellular organism growth", "Multicellular organism reproduction", "Multicellular organismal homeostasis", "Multicellular organismal movement", "Multicellular organismal response to stress", "Multicellular organismal signaling", "Multivesicular body organization", "Multivesicular body sorting pathway", "Muscle adaptation", "Muscle cell apoptotic process", "Muscle cell cellular homeostasis", "Muscle cell development", "Muscle cell differentiation", "Muscle cell migration", "Muscle cell proliferation", "Muscle contraction", "Muscle hypertrophy", "Muscle hypertrophy in response to stress", "Muscle organ development", "Muscle organ morphogenesis", "Muscle structure development", "Muscle system process", "Muscle tissue development", "Myd88 dependent toll like receptor signaling pathway", "Myelin assembly", "Myelin maintenance", "Myeloid cell activation involved in immune response", "Myeloid cell apoptotic process", "Myeloid cell development", "Myeloid cell differentiation", "Myeloid cell homeostasis", "Myeloid dendritic cell activation", "Myeloid dendritic cell cytokine production", "Myeloid leukocyte activation", "Myeloid leukocyte cytokine production", "Myeloid leukocyte differentiation", "Myeloid leukocyte mediated immunity", "Myeloid leukocyte migration", "Myeloid progenitor cell differentiation", "Myoblast differentiation", "Myoblast fusion", "Myoblast migration", "Myofibroblast differentiation", "Myosin filament organization", "Myotube cell development", "Myotube differentiation", "N acetylglucosamine metabolic process", "N acetylneuraminate catabolic process", "N acetylneuraminate metabolic process", "N acylethanolamine metabolic process", "N glycan processing", "N terminal peptidyl methionine acetylation", "N terminal protein amino acid acetylation", "N terminal protein amino acid modification", "N terminal protein lipidation", "Nad biosynthesis via nicotinamide riboside salvage pathway", "Nad metabolic process", "Nadh dehydrogenase complex assembly", "Nadh metabolic process", "Nadh oxidation", "Nadh regeneration", "Nadp metabolic process", "Nadph regeneration", "Natural killer cell activation", "Natural killer cell activation involved in immune response", "Natural killer cell degranulation", "Natural killer cell differentiation", "Natural killer cell mediated immunity", "Ncrna 3 end processing", "Ncrna catabolic process", "Ncrna export from nucleus", "Ncrna metabolic process", "Ncrna processing", "Ncrna transcription", "Necroptotic signaling pathway", "Necrotic cell death", "Negative chemotaxis", "Negative regulation by host of viral genome replication", "Negative regulation by host of viral process", "Negative regulation by host of viral transcription", "Negative regulation of actin filament bundle assembly", "Negative regulation of actin filament depolymerization", "Negative regulation of actin filament polymerization", "Negative regulation of actin nucleation", "Negative regulation of activated t cell proliferation", "Negative regulation of activin receptor signaling pathway", "Negative regulation of adaptive immune response", "Negative regulation of adenylate cyclase activating adrenergic receptor signaling pathway", "Negative regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Negative regulation of adenylate cyclase activity", "Negative regulation of alcohol biosynthetic process", "Negative regulation of alpha beta t cell activation", "Negative regulation of alpha beta t cell differentiation", "Negative regulation of alpha beta t cell proliferation", "Negative regulation of amine transport", "Negative regulation of amino acid transport", "Negative regulation of amyloid beta clearance", "Negative regulation of amyloid fibril formation", "Negative regulation of amyloid precursor protein biosynthetic process", "Negative regulation of amyloid precursor protein catabolic process", "Negative regulation of androgen receptor signaling pathway", "Negative regulation of anion transmembrane transport", "Negative regulation of anion transport", "Negative regulation of anoikis", "Negative regulation of antigen receptor mediated signaling pathway", "Negative regulation of apoptotic signaling pathway", "Negative regulation of arp2 3 complex mediated actin nucleation", "Negative regulation of astrocyte activation", "Negative regulation of astrocyte differentiation", "Negative regulation of atp biosynthetic process", "Negative regulation of atp dependent activity", "Negative regulation of atp metabolic process", "Negative regulation of autophagosome assembly", "Negative regulation of autophagosome maturation", "Negative regulation of autophagy", "Negative regulation of autophagy of mitochondrion", "Negative regulation of axon extension", "Negative regulation of axonogenesis", "Negative regulation of b cell activation", "Negative regulation of b cell apoptotic process", "Negative regulation of b cell differentiation", "Negative regulation of b cell mediated immunity", "Negative regulation of b cell proliferation", "Negative regulation of bicellular tight junction assembly", "Negative regulation of binding", "Negative regulation of biomineralization", "Negative regulation of biosynthetic process", "Negative regulation of blood circulation", "Negative regulation of blood pressure", "Negative regulation of blood vessel endothelial cell migration", "Negative regulation of bmp signaling pathway", "Negative regulation of bone mineralization", "Negative regulation of bone remodeling", "Negative regulation of calcineurin mediated signaling", "Negative regulation of calcium ion dependent exocytosis", "Negative regulation of calcium ion import", "Negative regulation of calcium ion transmembrane transport", "Negative regulation of calcium ion transport", "Negative regulation of calcium ion transport into cytosol", "Negative regulation of calcium mediated signaling", "Negative regulation of camp dependent protein kinase activity", "Negative regulation of canonical wnt signaling pathway", "Negative regulation of carbohydrate metabolic process", "Negative regulation of cardiac muscle adaptation", "Negative regulation of cardiac muscle contraction", "Negative regulation of cardiac muscle tissue growth", "Negative regulation of cardiocyte differentiation", "Negative regulation of cartilage development", "Negative regulation of catabolic process", "Negative regulation of catalytic activity", "Negative regulation of cation channel activity", "Negative regulation of cd4 positive alpha beta t cell activation", "Negative regulation of cd4 positive alpha beta t cell differentiation", "Negative regulation of cell activation", "Negative regulation of cell adhesion", "Negative regulation of cell adhesion mediated by integrin", "Negative regulation of cell aging", "Negative regulation of cell cell adhesion", "Negative regulation of cell cycle", "Negative regulation of cell cycle checkpoint", "Negative regulation of cell cycle g1 s phase transition", "Negative regulation of cell cycle g2 m phase transition", "Negative regulation of cell cycle phase transition", "Negative regulation of cell cycle process", "Negative regulation of cell death", "Negative regulation of cell development", "Negative regulation of cell differentiation", "Negative regulation of cell division", "Negative regulation of cell growth", "Negative regulation of cell growth involved in cardiac muscle cell development", "Negative regulation of cell junction assembly", "Negative regulation of cell killing", "Negative regulation of cell matrix adhesion", "Negative regulation of cell migration involved in sprouting angiogenesis", "Negative regulation of cell morphogenesis involved in differentiation", "Negative regulation of cell population proliferation", "Negative regulation of cell projection organization", "Negative regulation of cell size", "Negative regulation of cell substrate adhesion", "Negative regulation of cell substrate junction organization", "Negative regulation of cell volume", "Negative regulation of cellular amide metabolic process", "Negative regulation of cellular catabolic process", "Negative regulation of cellular component organization", "Negative regulation of cellular macromolecule biosynthetic process", "Negative regulation of cellular protein catabolic process", "Negative regulation of cellular respiration", "Negative regulation of cellular response to growth factor stimulus", "Negative regulation of cellular response to hypoxia", "Negative regulation of cellular response to insulin stimulus", "Negative regulation of cellular senescence", "Negative regulation of centriole replication", "Negative regulation of centrosome duplication", "Negative regulation of ceramide biosynthetic process", "Negative regulation of chemokine mediated signaling pathway", "Negative regulation of chemokine production", "Negative regulation of chemotaxis", "Negative regulation of cholesterol metabolic process", "Negative regulation of chondrocyte differentiation", "Negative regulation of chromatin binding", "Negative regulation of chromatin organization", "Negative regulation of chromosome organization", "Negative regulation of cilium assembly", "Negative regulation of circadian rhythm", "Negative regulation of coagulation", "Negative regulation of cold induced thermogenesis", "Negative regulation of collateral sprouting", "Negative regulation of creb transcription factor activity", "Negative regulation of cyclic nucleotide phosphodiesterase activity", "Negative regulation of cyclin dependent protein serine threonine kinase activity", "Negative regulation of cysteine type endopeptidase activity", "Negative regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Negative regulation of cytokine production", "Negative regulation of cytokine production involved in immune response", "Negative regulation of cytokine production involved in inflammatory response", "Negative regulation of cytokinesis", "Negative regulation of cytoplasmic translation", "Negative regulation of cytoskeleton organization", "Negative regulation of cytosolic calcium ion concentration", "Negative regulation of defense response", "Negative regulation of defense response to virus", "Negative regulation of delayed rectifier potassium channel activity", "Negative regulation of dendrite development", "Negative regulation of dendrite morphogenesis", "Negative regulation of dendritic spine development", "Negative regulation of dendritic spine morphogenesis", "Negative regulation of dephosphorylation", "Negative regulation of developmental growth", "Negative regulation of developmental process", "Negative regulation of digestive system process", "Negative regulation of dna binding", "Negative regulation of dna binding transcription factor activity", "Negative regulation of dna biosynthetic process", "Negative regulation of dna damage checkpoint", "Negative regulation of dna damage response signal transduction by p53 class mediator", "Negative regulation of dna dependent dna replication", "Negative regulation of dna metabolic process", "Negative regulation of dna recombination", "Negative regulation of dna repair", "Negative regulation of dna replication", "Negative regulation of dna templated transcription elongation", "Negative regulation of dna templated transcription initiation", "Negative regulation of double strand break repair via homologous recombination", "Negative regulation of double strand break repair via nonhomologous end joining", "Negative regulation of endocytosis", "Negative regulation of endoplasmic reticulum calcium ion concentration", "Negative regulation of endoplasmic reticulum stress induced eif2 alpha phosphorylation", "Negative regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Negative regulation of endoplasmic reticulum unfolded protein response", "Negative regulation of endothelial cell apoptotic process", "Negative regulation of endothelial cell proliferation", "Negative regulation of epidermal growth factor activated receptor activity", "Negative regulation of epidermis development", "Negative regulation of epithelial cell apoptotic process", "Negative regulation of epithelial cell differentiation", "Negative regulation of epithelial cell migration", "Negative regulation of epithelial cell proliferation", "Negative regulation of epithelial to mesenchymal transition", "Negative regulation of erad pathway", "Negative regulation of erbb signaling pathway", "Negative regulation of erk1 and erk2 cascade", "Negative regulation of erythrocyte differentiation", "Negative regulation of establishment of protein localization", "Negative regulation of establishment of protein localization to mitochondrion", "Negative regulation of excitatory postsynaptic potential", "Negative regulation of execution phase of apoptosis", "Negative regulation of exocytosis", "Negative regulation of extrinsic apoptotic signaling pathway", "Negative regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Negative regulation of fat cell differentiation", "Negative regulation of fatty acid beta oxidation", "Negative regulation of fatty acid biosynthetic process", "Negative regulation of fatty acid metabolic process", "Negative regulation of fatty acid oxidation", "Negative regulation of fatty acid transport", "Negative regulation of fibroblast apoptotic process", "Negative regulation of fibroblast migration", "Negative regulation of fibroblast proliferation", "Negative regulation of filopodium assembly", "Negative regulation of g protein coupled receptor signaling pathway", "Negative regulation of g0 to g1 transition", "Negative regulation of gene expression", "Negative regulation of gene expression epigenetic", "Negative regulation of glial cell apoptotic process", "Negative regulation of glial cell differentiation", "Negative regulation of glial cell proliferation", "Negative regulation of gliogenesis", "Negative regulation of glucocorticoid metabolic process", "Negative regulation of gluconeogenesis", "Negative regulation of glucose import", "Negative regulation of glucose transmembrane transport", "Negative regulation of glycogen metabolic process", "Negative regulation of glycolytic process", "Negative regulation of glycoprotein metabolic process", "Negative regulation of golgi to plasma membrane protein transport", "Negative regulation of granulocyte chemotaxis", "Negative regulation of growth", "Negative regulation of gtpase activity", "Negative regulation of guanyl nucleotide exchange factor activity", "Negative regulation of heart rate", "Negative regulation of helicase activity", "Negative regulation of hematopoietic progenitor cell differentiation", "Negative regulation of hemopoiesis", "Negative regulation of hepatocyte apoptotic process", "Negative regulation of hexokinase activity", "Negative regulation of high voltage gated calcium channel activity", "Negative regulation of hippo signaling", "Negative regulation of histone acetylation", "Negative regulation of histone deacetylation", "Negative regulation of histone h3 k27 methylation", "Negative regulation of histone h3 k4 methylation", "Negative regulation of histone h3 k9 methylation", "Negative regulation of histone h3 k9 trimethylation", "Negative regulation of histone h4 acetylation", "Negative regulation of histone methylation", "Negative regulation of histone modification", "Negative regulation of histone phosphorylation", "Negative regulation of homotypic cell cell adhesion", "Negative regulation of hormone biosynthetic process", "Negative regulation of hormone metabolic process", "Negative regulation of hormone secretion", "Negative regulation of hydrogen peroxide mediated programmed cell death", "Negative regulation of hydrolase activity", "Negative regulation of hypoxia induced intrinsic apoptotic signaling pathway", "Negative regulation of i kappab kinase nf kappab signaling", "Negative regulation of immune effector process", "Negative regulation of immune response", "Negative regulation of immune system process", "Negative regulation of immunoglobulin production", "Negative regulation of inclusion body assembly", "Negative regulation of inflammatory response", "Negative regulation of inflammatory response to antigenic stimulus", "Negative regulation of innate immune response", "Negative regulation of insulin secretion involved in cellular response to glucose stimulus", "Negative regulation of interferon beta production", "Negative regulation of interferon gamma production", "Negative regulation of interleukin 1 beta production", "Negative regulation of interleukin 1 mediated signaling pathway", "Negative regulation of interleukin 1 production", "Negative regulation of interleukin 12 production", "Negative regulation of interleukin 2 production", "Negative regulation of interleukin 6 production", "Negative regulation of interleukin 8 production", "Negative regulation of intracellular estrogen receptor signaling pathway", "Negative regulation of intracellular protein transport", "Negative regulation of intracellular signal transduction", "Negative regulation of intracellular steroid hormone receptor signaling pathway", "Negative regulation of intracellular transport", "Negative regulation of intrinsic apoptotic signaling pathway", "Negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Negative regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Negative regulation of ion transmembrane transport", "Negative regulation of ion transmembrane transporter activity", "Negative regulation of ion transport", "Negative regulation of ire1 mediated unfolded protein response", "Negative regulation of isotype switching", "Negative regulation of jnk cascade", "Negative regulation of jun kinase activity", "Negative regulation of keratinocyte differentiation", "Negative regulation of keratinocyte proliferation", "Negative regulation of kidney development", "Negative regulation of kinase activity", "Negative regulation of lamellipodium assembly", "Negative regulation of lamellipodium organization", "Negative regulation of leukocyte apoptotic process", "Negative regulation of leukocyte cell cell adhesion", "Negative regulation of leukocyte chemotaxis", "Negative regulation of leukocyte degranulation", "Negative regulation of leukocyte mediated immunity", "Negative regulation of leukocyte migration", "Negative regulation of leukocyte proliferation", "Negative regulation of lipase activity", "Negative regulation of lipid biosynthetic process", "Negative regulation of lipid catabolic process", "Negative regulation of lipid kinase activity", "Negative regulation of lipid localization", "Negative regulation of lipid metabolic process", "Negative regulation of lipid storage", "Negative regulation of lipid transport", "Negative regulation of lipopolysaccharide mediated signaling pathway", "Negative regulation of lipoprotein lipase activity", "Negative regulation of lipoprotein particle clearance", "Negative regulation of locomotion", "Negative regulation of low density lipoprotein particle clearance", "Negative regulation of lyase activity", "Negative regulation of lymphocyte activation", "Negative regulation of lymphocyte apoptotic process", "Negative regulation of lymphocyte differentiation", "Negative regulation of lymphocyte mediated immunity", "Negative regulation of lymphocyte migration", "Negative regulation of macroautophagy", "Negative regulation of macrophage activation", "Negative regulation of macrophage chemotaxis", "Negative regulation of macrophage migration", "Negative regulation of map kinase activity", "Negative regulation of mapk cascade", "Negative regulation of mast cell activation", "Negative regulation of mast cell activation involved in immune response", "Negative regulation of mast cell degranulation", "Negative regulation of megakaryocyte differentiation", "Negative regulation of meiotic cell cycle", "Negative regulation of meiotic nuclear division", "Negative regulation of membrane permeability", "Negative regulation of membrane potential", "Negative regulation of membrane protein ectodomain proteolysis", "Negative regulation of mesenchymal cell proliferation", "Negative regulation of metalloendopeptidase activity", "Negative regulation of metallopeptidase activity", "Negative regulation of metaphase anaphase transition of cell cycle", "Negative regulation of mhc class ii biosynthetic process", "Negative regulation of microglial cell activation", "Negative regulation of microtubule polymerization", "Negative regulation of microtubule polymerization or depolymerization", "Negative regulation of mirna transcription", "Negative regulation of mitochondrial fusion", "Negative regulation of mitochondrial membrane permeability", "Negative regulation of mitochondrial membrane permeability involved in apoptotic process", "Negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Negative regulation of mitochondrion organization", "Negative regulation of mitophagy", "Negative regulation of mitotic cell cycle", "Negative regulation of mitotic cell cycle phase transition", "Negative regulation of molecular function", "Negative regulation of monocyte chemotactic protein 1 production", "Negative regulation of monocyte chemotaxis", "Negative regulation of monocyte differentiation", "Negative regulation of mononuclear cell migration", "Negative regulation of monooxygenase activity", "Negative regulation of mrna 3 end processing", "Negative regulation of mrna catabolic process", "Negative regulation of mrna metabolic process", "Negative regulation of mrna processing", "Negative regulation of mrna splicing via spliceosome", "Negative regulation of multicellular organismal process", "Negative regulation of muscle adaptation", "Negative regulation of muscle cell apoptotic process", "Negative regulation of muscle cell differentiation", "Negative regulation of muscle contraction", "Negative regulation of muscle hypertrophy", "Negative regulation of muscle organ development", "Negative regulation of muscle tissue development", "Negative regulation of myelination", "Negative regulation of myeloid cell apoptotic process", "Negative regulation of myeloid cell differentiation", "Negative regulation of myeloid leukocyte differentiation", "Negative regulation of myeloid leukocyte mediated immunity", "Negative regulation of myoblast differentiation", "Negative regulation of myosin light chain phosphatase activity", "Negative regulation of myotube differentiation", "Negative regulation of natural killer cell activation", "Negative regulation of natural killer cell mediated immunity", "Negative regulation of necrotic cell death", "Negative regulation of nervous system development", "Negative regulation of nervous system process", "Negative regulation of neural precursor cell proliferation", "Negative regulation of neuroblast proliferation", "Negative regulation of neuroinflammatory response", "Negative regulation of neuron apoptotic process", "Negative regulation of neuron death", "Negative regulation of neuron differentiation", "Negative regulation of neuron migration", "Negative regulation of neuron projection development", "Negative regulation of neuron projection regeneration", "Negative regulation of neurotransmitter secretion", "Negative regulation of neurotransmitter transport", "Negative regulation of neutrophil migration", "Negative regulation of nf kappab transcription factor activity", "Negative regulation of nik nf kappab signaling", "Negative regulation of nitric oxide metabolic process", "Negative regulation of nitric oxide synthase activity", "Negative regulation of notch signaling pathway", "Negative regulation of nuclear division", "Negative regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Negative regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Negative regulation of nuclease activity", "Negative regulation of nucleobase containing compound metabolic process", "Negative regulation of nucleocytoplasmic transport", "Negative regulation of nucleotide biosynthetic process", "Negative regulation of nucleotide metabolic process", "Negative regulation of oligodendrocyte differentiation", "Negative regulation of organ growth", "Negative regulation of organelle assembly", "Negative regulation of organelle organization", "Negative regulation of organic acid transport", "Negative regulation of ossification", "Negative regulation of osteoblast differentiation", "Negative regulation of osteoblast proliferation", "Negative regulation of osteoclast differentiation", "Negative regulation of oxidative phosphorylation", "Negative regulation of oxidative stress induced cell death", "Negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Negative regulation of oxidative stress induced neuron death", "Negative regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway", "Negative regulation of oxidoreductase activity", "Negative regulation of p38mapk cascade", "Negative regulation of pathway restricted smad protein phosphorylation", "Negative regulation of peptidase activity", "Negative regulation of peptide secretion", "Negative regulation of peptidyl lysine acetylation", "Negative regulation of peptidyl serine phosphorylation", "Negative regulation of peptidyl threonine phosphorylation", "Negative regulation of peptidyl tyrosine phosphorylation", "Negative regulation of perk mediated unfolded protein response", "Negative regulation of phagocytosis", "Negative regulation of phosphatase activity", "Negative regulation of phosphatidylinositol 3 kinase signaling", "Negative regulation of phospholipase activity", "Negative regulation of phospholipid metabolic process", "Negative regulation of phosphoprotein phosphatase activity", "Negative regulation of phosphorus metabolic process", "Negative regulation of phosphorylation", "Negative regulation of plasma membrane bounded cell projection assembly", "Negative regulation of platelet activation", "Negative regulation of platelet derived growth factor receptor signaling pathway", "Negative regulation of posttranscriptional gene silencing", "Negative regulation of potassium ion transmembrane transport", "Negative regulation of potassium ion transport", "Negative regulation of production of mirnas involved in gene silencing by mirna", "Negative regulation of production of molecular mediator of immune response", "Negative regulation of programmed necrotic cell death", "Negative regulation of prostaglandin biosynthetic process", "Negative regulation of proteasomal protein catabolic process", "Negative regulation of proteasomal ubiquitin dependent protein catabolic process", "Negative regulation of protein acetylation", "Negative regulation of protein autophosphorylation", "Negative regulation of protein binding", "Negative regulation of protein catabolic process", "Negative regulation of protein containing complex assembly", "Negative regulation of protein containing complex disassembly", "Negative regulation of protein dephosphorylation", "Negative regulation of protein exit from endoplasmic reticulum", "Negative regulation of protein export from nucleus", "Negative regulation of protein import into nucleus", "Negative regulation of protein k63 linked ubiquitination", "Negative regulation of protein kinase activity by regulation of protein phosphorylation", "Negative regulation of protein kinase b signaling", "Negative regulation of protein localization", "Negative regulation of protein localization to cell periphery", "Negative regulation of protein localization to cell surface", "Negative regulation of protein localization to membrane", "Negative regulation of protein localization to microtubule", "Negative regulation of protein localization to nucleus", "Negative regulation of protein maturation", "Negative regulation of protein metabolic process", "Negative regulation of protein modification by small protein conjugation or removal", "Negative regulation of protein modification process", "Negative regulation of protein polymerization", "Negative regulation of protein polyubiquitination", "Negative regulation of protein secretion", "Negative regulation of protein serine threonine kinase activity", "Negative regulation of protein sumoylation", "Negative regulation of protein targeting to membrane", "Negative regulation of protein targeting to mitochondrion", "Negative regulation of protein tyrosine kinase activity", "Negative regulation of proteolysis", "Negative regulation of proteolysis involved in cellular protein catabolic process", "Negative regulation of reactive oxygen species biosynthetic process", "Negative regulation of reactive oxygen species metabolic process", "Negative regulation of receptor binding", "Negative regulation of receptor internalization", "Negative regulation of receptor mediated endocytosis", "Negative regulation of receptor recycling", "Negative regulation of receptor signaling pathway via jak stat", "Negative regulation of receptor signaling pathway via stat", "Negative regulation of regulated secretory pathway", "Negative regulation of release of cytochrome c from mitochondria", "Negative regulation of reproductive process", "Negative regulation of respiratory burst", "Negative regulation of respiratory burst involved in inflammatory response", "Negative regulation of response to biotic stimulus", "Negative regulation of response to cytokine stimulus", "Negative regulation of response to dna damage stimulus", "Negative regulation of response to endoplasmic reticulum stress", "Negative regulation of response to external stimulus", "Negative regulation of response to food", "Negative regulation of response to oxidative stress", "Negative regulation of response to reactive oxygen species", "Negative regulation of response to stimulus", "Negative regulation of response to wounding", "Negative regulation of retinoic acid receptor signaling pathway", "Negative regulation of rho protein signal transduction", "Negative regulation of ribosome biogenesis", "Negative regulation of rig i signaling pathway", "Negative regulation of rna catabolic process", "Negative regulation of rna splicing", "Negative regulation of ruffle assembly", "Negative regulation of ryanodine sensitive calcium release channel activity", "Negative regulation of schwann cell proliferation", "Negative regulation of secondary metabolite biosynthetic process", "Negative regulation of secretion", "Negative regulation of sequestering of triglyceride", "Negative regulation of signal transduction by p53 class mediator", "Negative regulation of signal transduction in absence of ligand", "Negative regulation of signaling", "Negative regulation of signaling receptor activity", "Negative regulation of single stranded viral rna replication via double stranded dna intermediate", "Negative regulation of sister chromatid cohesion", "Negative regulation of smad protein signal transduction", "Negative regulation of small gtpase mediated signal transduction", "Negative regulation of small molecule metabolic process", "Negative regulation of smooth muscle cell apoptotic process", "Negative regulation of smooth muscle cell differentiation", "Negative regulation of smooth muscle cell migration", "Negative regulation of smooth muscle cell proliferation", "Negative regulation of smoothened signaling pathway", "Negative regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Negative regulation of sodium ion transmembrane transport", "Negative regulation of sodium ion transport", "Negative regulation of sphingolipid biosynthetic process", "Negative regulation of sprouting angiogenesis", "Negative regulation of stem cell differentiation", "Negative regulation of steroid metabolic process", "Negative regulation of sterol transport", "Negative regulation of stress activated protein kinase signaling cascade", "Negative regulation of striated muscle cell apoptotic process", "Negative regulation of striated muscle cell differentiation", "Negative regulation of striated muscle contraction", "Negative regulation of supramolecular fiber organization", "Negative regulation of synapse organization", "Negative regulation of synaptic transmission", "Negative regulation of synaptic transmission glutamatergic", "Negative regulation of synaptic vesicle exocytosis", "Negative regulation of systemic arterial blood pressure", "Negative regulation of t cell apoptotic process", "Negative regulation of t cell differentiation", "Negative regulation of t cell proliferation", "Negative regulation of t cell receptor signaling pathway", "Negative regulation of t helper cell differentiation", "Negative regulation of telomerase activity", "Negative regulation of telomere capping", "Negative regulation of telomere maintenance", "Negative regulation of telomere maintenance via telomerase", "Negative regulation of telomere maintenance via telomere lengthening", "Negative regulation of thymocyte apoptotic process", "Negative regulation of tissue remodeling", "Negative regulation of toll like receptor signaling pathway", "Negative regulation of tor signaling", "Negative regulation of transcription by competitive promoter binding", "Negative regulation of transcription by rna polymerase i", "Negative regulation of transcription by rna polymerase ii", "Negative regulation of transcription from rna polymerase ii promoter in response to stress", "Negative regulation of transcription initiation from rna polymerase ii promoter", "Negative regulation of transcription regulatory region dna binding", "Negative regulation of transferase activity", "Negative regulation of transforming growth factor beta production", "Negative regulation of transforming growth factor beta receptor signaling pathway", "Negative regulation of transforming growth factor beta1 production", "Negative regulation of translational elongation", "Negative regulation of translational initiation", "Negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Negative regulation of transmembrane transport", "Negative regulation of transport", "Negative regulation of transporter activity", "Negative regulation of trophoblast cell migration", "Negative regulation of tubulin deacetylation", "Negative regulation of tumor necrosis factor superfamily cytokine production", "Negative regulation of type 2 immune response", "Negative regulation of type b pancreatic cell apoptotic process", "Negative regulation of type i interferon mediated signaling pathway", "Negative regulation of type i interferon production", "Negative regulation of tyrosine phosphorylation of stat protein", "Negative regulation of ubiquitin dependent protein catabolic process", "Negative regulation of ubiquitin protein ligase activity", "Negative regulation of ubiquitin protein transferase activity", "Negative regulation of vascular associated smooth muscle cell apoptotic process", "Negative regulation of vascular associated smooth muscle cell differentiation", "Negative regulation of vascular associated smooth muscle cell migration", "Negative regulation of vascular associated smooth muscle cell proliferation", "Negative regulation of vascular endothelial growth factor production", "Negative regulation of vascular endothelial growth factor receptor signaling pathway", "Negative regulation of vascular permeability", "Negative regulation of vascular wound healing", "Negative regulation of vasculature development", "Negative regulation of viral entry into host cell", "Negative regulation of viral genome replication", "Negative regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Negative regulation of viral life cycle", "Negative regulation of viral process", "Negative regulation of viral transcription", "Negative regulation of vitamin d biosynthetic process", "Negative regulation of vitamin metabolic process", "Negative regulation of voltage gated calcium channel activity", "Negative regulation of voltage gated potassium channel activity", "Negative regulation of wnt signaling pathway", "Negative regulation of wound healing", "Nephric duct development", "Nephric duct morphogenesis", "Nephron development", "Nephron epithelium development", "Nephron morphogenesis", "Nephron tubule epithelial cell differentiation", "Nephron tubule formation", "Nerve development", "Nerve growth factor signaling pathway", "Nervous system process", "Nervous system process involved in regulation of systemic arterial blood pressure", "Netrin activated signaling pathway", "Neural crest cell differentiation", "Neural crest cell migration", "Neural crest formation", "Neural nucleus development", "Neural plate development", "Neural plate morphogenesis", "Neural precursor cell proliferation", "Neural retina development", "Neural tube development", "Neural tube formation", "Neural tube patterning", "Neuroblast division", "Neuroblast proliferation", "Neuroendocrine cell differentiation", "Neuroepithelial cell differentiation", "Neurofilament cytoskeleton organization", "Neurogenesis", "Neuroinflammatory response", "Neuromuscular junction development", "Neuromuscular process", "Neuromuscular process controlling balance", "Neuromuscular process controlling posture", "Neuromuscular synaptic transmission", "Neuron apoptotic process", "Neuron cellular homeostasis", "Neuron death", "Neuron death in response to hydrogen peroxide", "Neuron death in response to oxidative stress", "Neuron development", "Neuron differentiation", "Neuron fate commitment", "Neuron fate determination", "Neuron fate specification", "Neuron intrinsic apoptotic signaling pathway in response to oxidative stress", "Neuron maturation", "Neuron migration", "Neuron neuron synaptic transmission", "Neuron projection arborization", "Neuron projection extension", "Neuron projection extension involved in neuron projection guidance", "Neuron projection guidance", "Neuron projection maintenance", "Neuron projection organization", "Neuron projection regeneration", "Neuron recognition", "Neuronal action potential", "Neuronal ion channel clustering", "Neuronal signal transduction", "Neuronal stem cell population maintenance", "Neuropeptide signaling pathway", "Neurotransmitter biosynthetic process", "Neurotransmitter catabolic process", "Neurotransmitter gated ion channel clustering", "Neurotransmitter metabolic process", "Neurotransmitter receptor internalization", "Neurotransmitter receptor localization to postsynaptic specialization membrane", "Neurotransmitter receptor transport", "Neurotransmitter receptor transport endosome to postsynaptic membrane", "Neurotransmitter receptor transport postsynaptic endosome to lysosome", "Neurotransmitter receptor transport to plasma membrane", "Neurotransmitter reuptake", "Neurotransmitter secretion", "Neurotransmitter transport", "Neurotransmitter uptake", "Neurotrophin production", "Neurotrophin signaling pathway", "Neurotrophin trk receptor signaling pathway", "Neutral amino acid transport", "Neutral lipid biosynthetic process", "Neutral lipid catabolic process", "Neutral lipid metabolic process", "Neutrophil activation involved in immune response", "Neutrophil apoptotic process", "Neutrophil chemotaxis", "Neutrophil clearance", "Neutrophil degranulation", "Neutrophil differentiation", "Neutrophil homeostasis", "Neutrophil mediated immunity", "Neutrophil migration", "Nik nf kappab signaling", "Nitric oxide mediated signal transduction", "Nitric oxide synthase biosynthetic process", "Nitrogen compound transport", "Nitrogen utilization", "Nk t cell activation", "Nk t cell differentiation", "Nls bearing protein import into nucleus", "Non canonical wnt signaling pathway", "Non lytic viral release", "Non membrane bounded organelle assembly", "Non motile cilium assembly", "Nonribosomal peptide biosynthetic process", "Noradrenergic neuron development", "Noradrenergic neuron differentiation", "Nose development", "Notch receptor processing", "Notch signaling pathway", "Notochord development", "Nuclear body organization", "Nuclear chromosome segregation", "Nuclear envelope organization", "Nuclear export", "Nuclear membrane organization", "Nuclear membrane reassembly", "Nuclear migration", "Nuclear ncrna surveillance", "Nuclear pore complex assembly", "Nuclear pore organization", "Nuclear transcribed mrna catabolic process", "Nuclear transcribed mrna catabolic process deadenylation dependent decay", "Nuclear transcribed mrna catabolic process deadenylation independent decay", "Nuclear transcribed mrna catabolic process exonucleolytic", "Nuclear transcribed mrna catabolic process exonucleolytic 3 5", "Nuclear transcribed mrna catabolic process nonsense mediated decay", "Nuclear transcribed mrna poly a tail shortening", "Nuclear transport", "Nucleic acid phosphodiester bond hydrolysis", "Nucleobase biosynthetic process", "Nucleobase catabolic process", "Nucleobase containing compound transport", "Nucleobase containing small molecule biosynthetic process", "Nucleobase containing small molecule catabolic process", "Nucleobase containing small molecule interconversion", "Nucleobase containing small molecule metabolic process", "Nucleobase metabolic process", "Nucleobase transport", "Nucleolar chromatin organization", "Nucleolar large rrna transcription by rna polymerase i", "Nucleolus organization", "Nucleoside bisphosphate biosynthetic process", "Nucleoside bisphosphate catabolic process", "Nucleoside bisphosphate metabolic process", "Nucleoside catabolic process", "Nucleoside diphosphate biosynthetic process", "Nucleoside diphosphate catabolic process", "Nucleoside diphosphate metabolic process", "Nucleoside metabolic process", "Nucleoside monophosphate biosynthetic process", "Nucleoside monophosphate catabolic process", "Nucleoside monophosphate metabolic process", "Nucleoside monophosphate phosphorylation", "Nucleoside phosphate biosynthetic process", "Nucleoside phosphate catabolic process", "Nucleoside salvage", "Nucleoside triphosphate biosynthetic process", "Nucleoside triphosphate catabolic process", "Nucleoside triphosphate metabolic process", "Nucleosome assembly", "Nucleosome mobilization", "Nucleosome organization", "Nucleosome positioning", "Nucleotide binding domain leucine rich repeat containing receptor signaling pathway", "Nucleotide binding oligomerization domain containing 2 signaling pathway", "Nucleotide excision repair", "Nucleotide excision repair dna gap filling", "Nucleotide excision repair dna incision", "Nucleotide phosphorylation", "Nucleotide salvage", "Nucleotide sugar biosynthetic process", "Nucleotide sugar metabolic process", "Nucleotide sugar transmembrane transport", "Nucleotide transmembrane transport", "Nucleotide transport", "Nucleus localization", "Nucleus organization", "O glycan processing", "Observational learning", "Odontoblast differentiation", "Odontogenesis", "Odontogenesis of dentin containing tooth", "Olefinic compound metabolic process", "Olfactory behavior", "Olfactory bulb interneuron development", "Olfactory bulb interneuron differentiation", "Olfactory lobe development", "Oligodendrocyte development", "Oligodendrocyte differentiation", "Oligodendrocyte progenitor proliferation", "Oligopeptide transport", "Oligosaccharide biosynthetic process", "Oligosaccharide catabolic process", "Oligosaccharide lipid intermediate biosynthetic process", "Oligosaccharide metabolic process", "One carbon metabolic process", "Oocyte construction", "Oocyte differentiation", "Oocyte maturation", "Oogenesis", "Opsonization", "Optic nerve development", "Organ growth", "Organ induction", "Organ or tissue specific immune response", "Organelle assembly", "Organelle disassembly", "Organelle fission", "Organelle fusion", "Organelle inheritance", "Organelle localization", "Organelle membrane fusion", "Organelle transport along microtubule", "Organic acid biosynthetic process", "Organic acid catabolic process", "Organic acid metabolic process", "Organic acid transmembrane transport", "Organic acid transport", "Organic anion transport", "Organic cation transport", "Organic cyclic compound catabolic process", "Organic hydroxy compound biosynthetic process", "Organic hydroxy compound catabolic process", "Organic hydroxy compound metabolic process", "Organic hydroxy compound transport", "Organism emergence from protective structure", "Organonitrogen compound biosynthetic process", "Organonitrogen compound catabolic process", "Organophosphate biosynthetic process", "Organophosphate catabolic process", "Organophosphate ester transport", "Organophosphate metabolic process", "Ornithine metabolic process", "Ornithine transport", "Ossification", "Osteoblast differentiation", "Osteoblast proliferation", "Osteoclast development", "Osteoclast differentiation", "Otolith development", "Outer dynein arm assembly", "Outer ear morphogenesis", "Outer mitochondrial membrane organization", "Outflow tract morphogenesis", "Ovarian follicle development", "Oviduct development", "Ovulation", "Ovulation cycle", "Ovulation cycle process", "Ovulation from ovarian follicle", "Oxaloacetate metabolic process", "Oxaloacetate transport", "Oxidative demethylation", "Oxidative dna demethylation", "Oxidative phosphorylation", "Oxidative rna demethylation", "Oxygen homeostasis", "P body assembly", "P38mapk cascade", "Pallium development", "Pancreas development", "Pancreatic juice secretion", "Pantothenate metabolic process", "Parallel actin filament bundle assembly", "Paranodal junction assembly", "Parathyroid gland development", "Paraxial mesoderm development", "Paraxial mesoderm formation", "Paraxial mesoderm morphogenesis", "Parkin mediated stimulation of mitophagy in response to mitochondrial depolarization", "Pathway restricted smad protein phosphorylation", "Pattern recognition receptor signaling pathway", "Pattern specification involved in kidney development", "Pattern specification process", "Penetration of zona pellucida", "Penile erection", "Pentose catabolic process", "Pentose metabolic process", "Pentose phosphate shunt", "Pentose phosphate shunt non oxidative branch", "Peptide antigen assembly with mhc protein complex", "Peptide biosynthetic process", "Peptide catabolic process", "Peptide cross linking", "Peptide metabolic process", "Peptide modification", "Peptide transport", "Peptidyl amino acid modification", "Peptidyl arginine methylation", "Peptidyl arginine methylation to asymmetrical dimethyl arginine", "Peptidyl arginine modification", "Peptidyl arginine n methylation", "Peptidyl asparagine modification", "Peptidyl cysteine modification", "Peptidyl diphthamide biosynthetic process from peptidyl histidine", "Peptidyl glutamic acid modification", "Peptidyl glutamine methylation", "Peptidyl histidine modification", "Peptidyl lysine acetylation", "Peptidyl lysine deacetylation", "Peptidyl lysine dimethylation", "Peptidyl lysine hydroxylation", "Peptidyl lysine methylation", "Peptidyl lysine modification", "Peptidyl lysine monomethylation", "Peptidyl lysine trimethylation", "Peptidyl methionine modification", "Peptidyl proline hydroxylation", "Peptidyl proline hydroxylation to 4 hydroxy l proline", "Peptidyl proline modification", "Peptidyl serine autophosphorylation", "Peptidyl serine dephosphorylation", "Peptidyl serine modification", "Peptidyl threonine dephosphorylation", "Peptidyl threonine modification", "Peptidyl tyrosine autophosphorylation", "Peptidyl tyrosine dephosphorylation", "Peptidyl tyrosine dephosphorylation involved in inactivation of protein kinase activity", "Peptidyl tyrosine modification", "Pericyte cell differentiation", "Peripheral nervous system axon regeneration", "Peripheral nervous system development", "Peripheral nervous system myelin maintenance", "Perk mediated unfolded protein response", "Peroxisomal transport", "Peroxisome fission", "Peroxisome organization", "Peroxisome proliferator activated receptor signaling pathway", "Ph reduction", "Phagocytosis", "Phagocytosis recognition", "Phagolysosome assembly", "Phagosome acidification", "Phagosome lysosome fusion", "Phagosome maturation", "Pharyngeal system development", "Phenol containing compound biosynthetic process", "Phenol containing compound catabolic process", "Phenol containing compound metabolic process", "Phenotypic switching", "Phosphagen metabolic process", "Phosphate ion transmembrane transport", "Phosphate ion transport", "Phosphatidic acid metabolic process", "Phosphatidylcholine acyl chain remodeling", "Phosphatidylcholine biosynthetic process", "Phosphatidylcholine catabolic process", "Phosphatidylcholine metabolic process", "Phosphatidylethanolamine biosynthetic process", "Phosphatidylethanolamine metabolic process", "Phosphatidylglycerol acyl chain remodeling", "Phosphatidylglycerol biosynthetic process", "Phosphatidylglycerol metabolic process", "Phosphatidylinositol 3 kinase signaling", "Phosphatidylinositol 3 phosphate biosynthetic process", "Phosphatidylinositol acyl chain remodeling", "Phosphatidylinositol biosynthetic process", "Phosphatidylinositol dephosphorylation", "Phosphatidylinositol metabolic process", "Phosphatidylinositol phosphate biosynthetic process", "Phosphatidylserine acyl chain remodeling", "Phosphatidylserine metabolic process", "Phospholipase c activating dopamine receptor signaling pathway", "Phospholipase c activating g protein coupled receptor signaling pathway", "Phospholipid biosynthetic process", "Phospholipid catabolic process", "Phospholipid dephosphorylation", "Phospholipid homeostasis", "Phospholipid metabolic process", "Phospholipid transport", "Phosphorylation", "Phosphorylation of rna polymerase ii c terminal domain", "Photoperiodism", "Photoreceptor cell development", "Photoreceptor cell differentiation", "Photoreceptor cell maintenance", "Photoreceptor cell outer segment organization", "Phototransduction", "Phototransduction visible light", "Physiological cardiac muscle hypertrophy", "Pigment accumulation", "Pigment biosynthetic process", "Pigment cell differentiation", "Pigment granule localization", "Pigment granule maturation", "Pigment granule organization", "Pigment metabolic process", "Pigmentation", "Pinocytosis", "Pirna metabolic process", "Pituitary gland development", "Placenta blood vessel development", "Placenta development", "Planar cell polarity pathway involved in neural tube closure", "Plasma lipoprotein particle clearance", "Plasma membrane fusion", "Plasma membrane organization", "Plasma membrane phospholipid scrambling", "Plasma membrane raft assembly", "Plasma membrane raft organization", "Plasma membrane repair", "Plasma membrane to endosome transport", "Plasma membrane tubulation", "Plasminogen activation", "Platelet activating factor metabolic process", "Platelet activation", "Platelet aggregation", "Platelet degranulation", "Platelet dense granule organization", "Platelet derived growth factor receptor alpha signaling pathway", "Platelet derived growth factor receptor beta signaling pathway", "Platelet derived growth factor receptor signaling pathway", "Platelet morphogenesis", "Plus end directed organelle transport along microtubule", "Pml body organization", "Podosome assembly", "Pointed end actin filament capping", "Polarized epithelial cell differentiation", "Poly a plus mrna export from nucleus", "Poly n acetyllactosamine metabolic process", "Polyadenylation dependent rna catabolic process", "Polyadenylation dependent snorna 3 end processing", "Polyamine biosynthetic process", "Polyamine metabolic process", "Polyamine transmembrane transport", "Polyamine transport", "Polyketide metabolic process", "Polyol biosynthetic process", "Polyol catabolic process", "Polyol metabolic process", "Polyprenol metabolic process", "Polysaccharide biosynthetic process", "Polysaccharide catabolic process", "Polysaccharide metabolic process", "Pons development", "Pore complex assembly", "Porphyrin containing compound metabolic process", "Positive chemotaxis", "Positive regulation by host of viral genome replication", "Positive regulation by host of viral process", "Positive regulation by host of viral transcription", "Positive regulation by symbiont of entry into host", "Positive regulation of 3 utr mediated mrna stabilization", "Positive regulation of actin cytoskeleton reorganization", "Positive regulation of actin filament bundle assembly", "Positive regulation of actin filament depolymerization", "Positive regulation of actin filament polymerization", "Positive regulation of actin nucleation", "Positive regulation of action potential", "Positive regulation of activated t cell proliferation", "Positive regulation of activin receptor signaling pathway", "Positive regulation of acute inflammatory response", "Positive regulation of acute inflammatory response to antigenic stimulus", "Positive regulation of adaptive immune response", "Positive regulation of adipose tissue development", "Positive regulation of alcohol biosynthetic process", "Positive regulation of alpha beta t cell activation", "Positive regulation of alpha beta t cell differentiation", "Positive regulation of alpha beta t cell proliferation", "Positive regulation of amine transport", "Positive regulation of amino acid transport", "Positive regulation of amyloid beta clearance", "Positive regulation of amyloid beta formation", "Positive regulation of amyloid precursor protein biosynthetic process", "Positive regulation of amyloid precursor protein catabolic process", "Positive regulation of animal organ morphogenesis", "Positive regulation of anion transmembrane transport", "Positive regulation of anion transport", "Positive regulation of anoikis", "Positive regulation of antigen receptor mediated signaling pathway", "Positive regulation of apoptotic dna fragmentation", "Positive regulation of apoptotic process involved in development", "Positive regulation of apoptotic process involved in morphogenesis", "Positive regulation of apoptotic signaling pathway", "Positive regulation of arp2 3 complex mediated actin nucleation", "Positive regulation of aspartic type peptidase activity", "Positive regulation of astrocyte differentiation", "Positive regulation of atp biosynthetic process", "Positive regulation of atp dependent activity", "Positive regulation of atp metabolic process", "Positive regulation of atpase coupled calcium transmembrane transporter activity", "Positive regulation of attachment of spindle microtubules to kinetochore", "Positive regulation of autophagy", "Positive regulation of autophagy of mitochondrion", "Positive regulation of axon extension", "Positive regulation of axonogenesis", "Positive regulation of b cell activation", "Positive regulation of b cell mediated immunity", "Positive regulation of b cell proliferation", "Positive regulation of basement membrane assembly involved in embryonic body morphogenesis", "Positive regulation of behavior", "Positive regulation of binding", "Positive regulation of biomineralization", "Positive regulation of blood brain barrier permeability", "Positive regulation of blood circulation", "Positive regulation of blood pressure", "Positive regulation of blood pressure by epinephrine norepinephrine", "Positive regulation of blood vessel endothelial cell migration", "Positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Positive regulation of bmp signaling pathway", "Positive regulation of bone mineralization", "Positive regulation of bone resorption", "Positive regulation of brown fat cell differentiation", "Positive regulation of calcineurin mediated signaling", "Positive regulation of calcium ion dependent exocytosis", "Positive regulation of calcium ion import", "Positive regulation of calcium ion transmembrane transport", "Positive regulation of calcium ion transmembrane transporter activity", "Positive regulation of calcium ion transport", "Positive regulation of calcium ion transport into cytosol", "Positive regulation of calcium mediated signaling", "Positive regulation of camp dependent protein kinase activity", "Positive regulation of camp mediated signaling", "Positive regulation of canonical wnt signaling pathway", "Positive regulation of carbohydrate metabolic process", "Positive regulation of cardiac muscle adaptation", "Positive regulation of cardiac muscle cell proliferation", "Positive regulation of cardioblast differentiation", "Positive regulation of cardiocyte differentiation", "Positive regulation of cartilage development", "Positive regulation of catabolic process", "Positive regulation of catalytic activity", "Positive regulation of catecholamine metabolic process", "Positive regulation of cation channel activity", "Positive regulation of cd4 positive alpha beta t cell activation", "Positive regulation of cd4 positive alpha beta t cell differentiation", "Positive regulation of cd8 positive alpha beta t cell activation", "Positive regulation of cell activation", "Positive regulation of cell adhesion", "Positive regulation of cell adhesion molecule production", "Positive regulation of cell aging", "Positive regulation of cell cell adhesion", "Positive regulation of cell cell adhesion mediated by cadherin", "Positive regulation of cell cycle", "Positive regulation of cell cycle checkpoint", "Positive regulation of cell cycle g1 s phase transition", "Positive regulation of cell cycle g2 m phase transition", "Positive regulation of cell cycle phase transition", "Positive regulation of cell cycle process", "Positive regulation of cell death", "Positive regulation of cell development", "Positive regulation of cell differentiation", "Positive regulation of cell division", "Positive regulation of cell growth", "Positive regulation of cell junction assembly", "Positive regulation of cell killing", "Positive regulation of cell matrix adhesion", "Positive regulation of cell migration by vascular endothelial growth factor signaling pathway", "Positive regulation of cell migration involved in sprouting angiogenesis", "Positive regulation of cell morphogenesis involved in differentiation", "Positive regulation of cell population proliferation", "Positive regulation of cell projection organization", "Positive regulation of cell size", "Positive regulation of cell substrate adhesion", "Positive regulation of cell substrate junction organization", "Positive regulation of cellular amide metabolic process", "Positive regulation of cellular amine metabolic process", "Positive regulation of cellular biosynthetic process", "Positive regulation of cellular carbohydrate metabolic process", "Positive regulation of cellular component biogenesis", "Positive regulation of cellular component organization", "Positive regulation of cellular extravasation", "Positive regulation of cellular ph reduction", "Positive regulation of cellular protein catabolic process", "Positive regulation of cellular respiration", "Positive regulation of cellular response to insulin stimulus", "Positive regulation of cellular response to transforming growth factor beta stimulus", "Positive regulation of centriole elongation", "Positive regulation of centriole replication", "Positive regulation of chemokine c c motif ligand 5 production", "Positive regulation of chemokine c x c motif ligand 2 production", "Positive regulation of chemokine production", "Positive regulation of chemotaxis", "Positive regulation of cholesterol biosynthetic process", "Positive regulation of cholesterol efflux", "Positive regulation of cholesterol metabolic process", "Positive regulation of cholesterol storage", "Positive regulation of chondrocyte differentiation", "Positive regulation of chromatin binding", "Positive regulation of chromatin organization", "Positive regulation of chromosome condensation", "Positive regulation of chromosome organization", "Positive regulation of chromosome segregation", "Positive regulation of chromosome separation", "Positive regulation of cilium assembly", "Positive regulation of circadian rhythm", "Positive regulation of clathrin dependent endocytosis", "Positive regulation of coagulation", "Positive regulation of cold induced thermogenesis", "Positive regulation of collagen metabolic process", "Positive regulation of collateral sprouting", "Positive regulation of complement activation", "Positive regulation of connective tissue replacement", "Positive regulation of cyclase activity", "Positive regulation of cyclic nucleotide phosphodiesterase activity", "Positive regulation of cyclin dependent protein kinase activity", "Positive regulation of cysteine type endopeptidase activity", "Positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Positive regulation of cytokine production", "Positive regulation of cytokine production involved in immune response", "Positive regulation of cytokine production involved in inflammatory response", "Positive regulation of cytokinesis", "Positive regulation of cytoplasmic translation", "Positive regulation of cytoplasmic transport", "Positive regulation of cytoskeleton organization", "Positive regulation of deacetylase activity", "Positive regulation of defense response", "Positive regulation of defense response to virus by host", "Positive regulation of dendrite development", "Positive regulation of dendrite morphogenesis", "Positive regulation of dendritic cell cytokine production", "Positive regulation of dendritic cell differentiation", "Positive regulation of dendritic spine development", "Positive regulation of dendritic spine morphogenesis", "Positive regulation of deoxyribonuclease activity", "Positive regulation of dephosphorylation", "Positive regulation of developmental growth", "Positive regulation of developmental pigmentation", "Positive regulation of developmental process", "Positive regulation of dna binding", "Positive regulation of dna binding transcription factor activity", "Positive regulation of dna biosynthetic process", "Positive regulation of dna catabolic process", "Positive regulation of dna damage response signal transduction by p53 class mediator", "Positive regulation of dna demethylation", "Positive regulation of dna dependent dna replication", "Positive regulation of dna ligation", "Positive regulation of dna metabolic process", "Positive regulation of dna methylation dependent heterochromatin assembly", "Positive regulation of dna recombination", "Positive regulation of dna repair", "Positive regulation of dna replication", "Positive regulation of dna templated transcription elongation", "Positive regulation of dna templated transcription initiation", "Positive regulation of dopamine receptor signaling pathway", "Positive regulation of double strand break repair", "Positive regulation of double strand break repair via homologous recombination", "Positive regulation of double strand break repair via nonhomologous end joining", "Positive regulation of early endosome to late endosome transport", "Positive regulation of embryonic development", "Positive regulation of endocytic recycling", "Positive regulation of endocytosis", "Positive regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Positive regulation of endoplasmic reticulum unfolded protein response", "Positive regulation of endothelial cell apoptotic process", "Positive regulation of endothelial cell chemotaxis", "Positive regulation of endothelial cell chemotaxis by vegf activated vascular endothelial growth factor receptor signaling pathway", "Positive regulation of endothelial cell development", "Positive regulation of endothelial cell differentiation", "Positive regulation of endothelial cell migration", "Positive regulation of endothelial cell proliferation", "Positive regulation of epidermal cell differentiation", "Positive regulation of epidermal growth factor activated receptor activity", "Positive regulation of epidermis development", "Positive regulation of epithelial cell apoptotic process", "Positive regulation of epithelial cell differentiation", "Positive regulation of epithelial cell migration", "Positive regulation of epithelial cell proliferation", "Positive regulation of epithelial cell proliferation involved in lung morphogenesis", "Positive regulation of epithelial cell proliferation involved in wound healing", "Positive regulation of epithelial to mesenchymal transition", "Positive regulation of er associated ubiquitin dependent protein catabolic process", "Positive regulation of erad pathway", "Positive regulation of erbb signaling pathway", "Positive regulation of erk1 and erk2 cascade", "Positive regulation of erythrocyte differentiation", "Positive regulation of establishment of protein localization", "Positive regulation of establishment of protein localization to mitochondrion", "Positive regulation of establishment of protein localization to telomere", "Positive regulation of excitatory postsynaptic potential", "Positive regulation of execution phase of apoptosis", "Positive regulation of exocytosis", "Positive regulation of exosomal secretion", "Positive regulation of extracellular matrix assembly", "Positive regulation of extracellular matrix constituent secretion", "Positive regulation of extracellular matrix disassembly", "Positive regulation of extracellular matrix organization", "Positive regulation of extrinsic apoptotic signaling pathway", "Positive regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Positive regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Positive regulation of fat cell differentiation", "Positive regulation of fatty acid beta oxidation", "Positive regulation of fatty acid biosynthetic process", "Positive regulation of fatty acid metabolic process", "Positive regulation of fatty acid oxidation", "Positive regulation of fatty acid transport", "Positive regulation of feeding behavior", "Positive regulation of fibroblast growth factor receptor signaling pathway", "Positive regulation of fibroblast migration", "Positive regulation of fibroblast proliferation", "Positive regulation of filopodium assembly", "Positive regulation of focal adhesion assembly", "Positive regulation of g protein coupled receptor signaling pathway", "Positive regulation of g0 to g1 transition", "Positive regulation of g1 s transition of mitotic cell cycle", "Positive regulation of gastrulation", "Positive regulation of gene expression", "Positive regulation of glial cell differentiation", "Positive regulation of glial cell migration", "Positive regulation of glial cell proliferation", "Positive regulation of gliogenesis", "Positive regulation of glucokinase activity", "Positive regulation of gluconeogenesis", "Positive regulation of glucose import", "Positive regulation of glucose metabolic process", "Positive regulation of glucose transmembrane transport", "Positive regulation of glutamate secretion", "Positive regulation of glycogen metabolic process", "Positive regulation of glycogen starch synthase activity", "Positive regulation of glycolytic process", "Positive regulation of glycoprotein metabolic process", "Positive regulation of golgi to plasma membrane protein transport", "Positive regulation of gonad development", "Positive regulation of granulocyte chemotaxis", "Positive regulation of granulocyte differentiation", "Positive regulation of growth", "Positive regulation of gtpase activity", "Positive regulation of hair follicle development", "Positive regulation of heart growth", "Positive regulation of heart rate", "Positive regulation of helicase activity", "Positive regulation of hematopoietic progenitor cell differentiation", "Positive regulation of hematopoietic stem cell proliferation", "Positive regulation of hemopoiesis", "Positive regulation of hepatocyte proliferation", "Positive regulation of heterotypic cell cell adhesion", "Positive regulation of hexokinase activity", "Positive regulation of hippo signaling", "Positive regulation of histone acetylation", "Positive regulation of histone deacetylation", "Positive regulation of histone h3 k27 methylation", "Positive regulation of histone h3 k4 methylation", "Positive regulation of histone h3 k9 acetylation", "Positive regulation of histone h3 k9 methylation", "Positive regulation of histone h4 acetylation", "Positive regulation of histone methylation", "Positive regulation of histone modification", "Positive regulation of histone phosphorylation", "Positive regulation of histone ubiquitination", "Positive regulation of homotypic cell cell adhesion", "Positive regulation of hormone biosynthetic process", "Positive regulation of hormone metabolic process", "Positive regulation of hormone secretion", "Positive regulation of humoral immune response", "Positive regulation of hydrogen peroxide metabolic process", "Positive regulation of hydrolase activity", "Positive regulation of i kappab kinase nf kappab signaling", "Positive regulation of i kappab phosphorylation", "Positive regulation of immune effector process", "Positive regulation of immune response", "Positive regulation of immune system process", "Positive regulation of immunoglobulin production", "Positive regulation of inclusion body assembly", "Positive regulation of inflammatory response", "Positive regulation of inflammatory response to antigenic stimulus", "Positive regulation of innate immune response", "Positive regulation of insulin like growth factor receptor signaling pathway", "Positive regulation of insulin secretion", "Positive regulation of insulin secretion involved in cellular response to glucose stimulus", "Positive regulation of integrin activation", "Positive regulation of integrin mediated signaling pathway", "Positive regulation of interferon alpha production", "Positive regulation of interferon beta production", "Positive regulation of interferon gamma production", "Positive regulation of interleukin 1 alpha production", "Positive regulation of interleukin 1 beta production", "Positive regulation of interleukin 1 production", "Positive regulation of interleukin 10 production", "Positive regulation of interleukin 12 production", "Positive regulation of interleukin 13 production", "Positive regulation of interleukin 17 production", "Positive regulation of interleukin 18 production", "Positive regulation of interleukin 2 production", "Positive regulation of interleukin 6 production", "Positive regulation of interleukin 8 production", "Positive regulation of intracellular lipid transport", "Positive regulation of intracellular protein transport", "Positive regulation of intracellular signal transduction", "Positive regulation of intracellular steroid hormone receptor signaling pathway", "Positive regulation of intracellular transport", "Positive regulation of intrinsic apoptotic signaling pathway", "Positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Positive regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Positive regulation of ion transmembrane transport", "Positive regulation of ion transport", "Positive regulation of ire1 mediated unfolded protein response", "Positive regulation of isotype switching", "Positive regulation of isotype switching to iga isotypes", "Positive regulation of isotype switching to igg isotypes", "Positive regulation of jnk cascade", "Positive regulation of jun kinase activity", "Positive regulation of keratinocyte differentiation", "Positive regulation of keratinocyte proliferation", "Positive regulation of kinase activity", "Positive regulation of lamellipodium assembly", "Positive regulation of lamellipodium morphogenesis", "Positive regulation of lamellipodium organization", "Positive regulation of leukocyte adhesion to vascular endothelial cell", "Positive regulation of leukocyte apoptotic process", "Positive regulation of leukocyte cell cell adhesion", "Positive regulation of leukocyte chemotaxis", "Positive regulation of leukocyte degranulation", "Positive regulation of leukocyte mediated immunity", "Positive regulation of leukocyte migration", "Positive regulation of leukocyte proliferation", "Positive regulation of ligase activity", "Positive regulation of lipase activity", "Positive regulation of lipid biosynthetic process", "Positive regulation of lipid catabolic process", "Positive regulation of lipid kinase activity", "Positive regulation of lipid localization", "Positive regulation of lipid metabolic process", "Positive regulation of lipid storage", "Positive regulation of lipid transport", "Positive regulation of lipopolysaccharide mediated signaling pathway", "Positive regulation of lipoprotein particle clearance", "Positive regulation of locomotion", "Positive regulation of long term neuronal synaptic plasticity", "Positive regulation of long term synaptic potentiation", "Positive regulation of low density lipoprotein receptor activity", "Positive regulation of lyase activity", "Positive regulation of lymphocyte anergy", "Positive regulation of lymphocyte apoptotic process", "Positive regulation of lymphocyte chemotaxis", "Positive regulation of lymphocyte differentiation", "Positive regulation of lymphocyte mediated immunity", "Positive regulation of lymphocyte migration", "Positive regulation of macroautophagy", "Positive regulation of macrophage activation", "Positive regulation of macrophage chemotaxis", "Positive regulation of macrophage cytokine production", "Positive regulation of macrophage derived foam cell differentiation", "Positive regulation of macrophage differentiation", "Positive regulation of macrophage migration", "Positive regulation of maintenance of sister chromatid cohesion", "Positive regulation of mammary gland epithelial cell proliferation", "Positive regulation of map kinase activity", "Positive regulation of mapk cascade", "Positive regulation of mast cell activation", "Positive regulation of mast cell activation involved in immune response", "Positive regulation of megakaryocyte differentiation", "Positive regulation of meiotic cell cycle", "Positive regulation of meiotic cell cycle phase transition", "Positive regulation of membrane depolarization", "Positive regulation of membrane permeability", "Positive regulation of membrane potential", "Positive regulation of membrane protein ectodomain proteolysis", "Positive regulation of mesenchymal cell proliferation", "Positive regulation of mesenchymal stem cell proliferation", "Positive regulation of metalloendopeptidase activity", "Positive regulation of metallopeptidase activity", "Positive regulation of metaphase anaphase transition of cell cycle", "Positive regulation of mhc class i biosynthetic process", "Positive regulation of mhc class ii biosynthetic process", "Positive regulation of microglial cell activation", "Positive regulation of microtubule binding", "Positive regulation of microtubule nucleation", "Positive regulation of microtubule polymerization or depolymerization", "Positive regulation of mirna catabolic process", "Positive regulation of mirna mediated gene silencing by inhibition of translation", "Positive regulation of mirna metabolic process", "Positive regulation of mirna transcription", "Positive regulation of mitochondrial calcium ion concentration", "Positive regulation of mitochondrial depolarization", "Positive regulation of mitochondrial fission", "Positive regulation of mitochondrial membrane potential", "Positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Positive regulation of mitochondrial translation", "Positive regulation of mitochondrion organization", "Positive regulation of mitophagy", "Positive regulation of mitophagy in response to mitochondrial depolarization", "Positive regulation of mitotic cell cycle", "Positive regulation of mitotic cell cycle phase transition", "Positive regulation of mitotic cell cycle spindle assembly checkpoint", "Positive regulation of mitotic nuclear division", "Positive regulation of molecular function", "Positive regulation of monocyte chemotaxis", "Positive regulation of monocyte differentiation", "Positive regulation of mononuclear cell migration", "Positive regulation of monooxygenase activity", "Positive regulation of morphogenesis of an epithelium", "Positive regulation of mrna 3 end processing", "Positive regulation of mrna metabolic process", "Positive regulation of mrna processing", "Positive regulation of mrna splicing via spliceosome", "Positive regulation of multicellular organism growth", "Positive regulation of multicellular organismal process", "Positive regulation of muscle adaptation", "Positive regulation of muscle cell apoptotic process", "Positive regulation of muscle cell differentiation", "Positive regulation of muscle contraction", "Positive regulation of muscle hypertrophy", "Positive regulation of muscle tissue development", "Positive regulation of myelination", "Positive regulation of myeloid cell apoptotic process", "Positive regulation of myeloid cell differentiation", "Positive regulation of myeloid leukocyte cytokine production involved in immune response", "Positive regulation of myeloid leukocyte differentiation", "Positive regulation of myeloid leukocyte mediated immunity", "Positive regulation of myoblast differentiation", "Positive regulation of myoblast fusion", "Positive regulation of myotube differentiation", "Positive regulation of nad p h oxidase activity", "Positive regulation of natural killer cell activation", "Positive regulation of natural killer cell mediated cytotoxicity", "Positive regulation of natural killer cell mediated immunity", "Positive regulation of necrotic cell death", "Positive regulation of nervous system development", "Positive regulation of nervous system process", "Positive regulation of neural precursor cell proliferation", "Positive regulation of neuroblast proliferation", "Positive regulation of neurogenesis", "Positive regulation of neuroinflammatory response", "Positive regulation of neuron apoptotic process", "Positive regulation of neuron death", "Positive regulation of neuron differentiation", "Positive regulation of neuron migration", "Positive regulation of neuron projection arborization", "Positive regulation of neuron projection development", "Positive regulation of neuron projection regeneration", "Positive regulation of neurotransmitter secretion", "Positive regulation of neurotransmitter transport", "Positive regulation of neurotransmitter uptake", "Positive regulation of neurotrophin trk receptor signaling pathway", "Positive regulation of neutrophil migration", "Positive regulation of nf kappab transcription factor activity", "Positive regulation of nik nf kappab signaling", "Positive regulation of nitric oxide mediated signal transduction", "Positive regulation of nitric oxide metabolic process", "Positive regulation of nitric oxide synthase activity", "Positive regulation of nitric oxide synthase biosynthetic process", "Positive regulation of nk t cell activation", "Positive regulation of nlrp3 inflammasome complex assembly", "Positive regulation of non motile cilium assembly", "Positive regulation of notch signaling pathway", "Positive regulation of nuclear cell cycle dna replication", "Positive regulation of nuclear division", "Positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Positive regulation of nuclease activity", "Positive regulation of nucleobase containing compound metabolic process", "Positive regulation of nucleobase containing compound transport", "Positive regulation of nucleocytoplasmic transport", "Positive regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Positive regulation of nucleotide binding oligomerization domain containing signaling pathway", "Positive regulation of nucleotide biosynthetic process", "Positive regulation of nucleotide metabolic process", "Positive regulation of oligodendrocyte differentiation", "Positive regulation of opsonization", "Positive regulation of organ growth", "Positive regulation of organelle assembly", "Positive regulation of organelle organization", "Positive regulation of organic acid transport", "Positive regulation of ossification", "Positive regulation of osteoblast differentiation", "Positive regulation of osteoblast proliferation", "Positive regulation of oxidative stress induced cell death", "Positive regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Positive regulation of oxidative stress induced neuron death", "Positive regulation of oxidoreductase activity", "Positive regulation of p38mapk cascade", "Positive regulation of pathway restricted smad protein phosphorylation", "Positive regulation of pattern recognition receptor signaling pathway", "Positive regulation of peptidase activity", "Positive regulation of peptide secretion", "Positive regulation of peptidyl lysine acetylation", "Positive regulation of peptidyl serine phosphorylation", "Positive regulation of peptidyl threonine phosphorylation", "Positive regulation of peptidyl tyrosine phosphorylation", "Positive regulation of peroxisome proliferator activated receptor signaling pathway", "Positive regulation of phagocytosis", "Positive regulation of phosphatase activity", "Positive regulation of phosphatidylinositol 3 kinase signaling", "Positive regulation of phospholipase a2 activity", "Positive regulation of phospholipase activity", "Positive regulation of phospholipid biosynthetic process", "Positive regulation of phospholipid metabolic process", "Positive regulation of phospholipid translocation", "Positive regulation of phosphoprotein phosphatase activity", "Positive regulation of phosphorus metabolic process", "Positive regulation of pinocytosis", "Positive regulation of plasma membrane bounded cell projection assembly", "Positive regulation of plasminogen activation", "Positive regulation of platelet aggregation", "Positive regulation of platelet derived growth factor receptor signaling pathway", "Positive regulation of podosome assembly", "Positive regulation of posttranscriptional gene silencing", "Positive regulation of potassium ion import across plasma membrane", "Positive regulation of potassium ion transmembrane transporter activity", "Positive regulation of potassium ion transport", "Positive regulation of production of mirnas involved in gene silencing by mirna", "Positive regulation of production of molecular mediator of immune response", "Positive regulation of programmed necrotic cell death", "Positive regulation of prostaglandin biosynthetic process", "Positive regulation of proteasomal ubiquitin dependent protein catabolic process", "Positive regulation of protein acetylation", "Positive regulation of protein autophosphorylation", "Positive regulation of protein binding", "Positive regulation of protein catabolic process", "Positive regulation of protein catabolic process in the vacuole", "Positive regulation of protein containing complex assembly", "Positive regulation of protein containing complex disassembly", "Positive regulation of protein deacetylation", "Positive regulation of protein dephosphorylation", "Positive regulation of protein depolymerization", "Positive regulation of protein deubiquitination", "Positive regulation of protein exit from endoplasmic reticulum", "Positive regulation of protein export from nucleus", "Positive regulation of protein glycosylation", "Positive regulation of protein import", "Positive regulation of protein k63 linked ubiquitination", "Positive regulation of protein kinase a signaling", "Positive regulation of protein kinase activity", "Positive regulation of protein kinase b signaling", "Positive regulation of protein kinase c signaling", "Positive regulation of protein localization", "Positive regulation of protein localization to cell cortex", "Positive regulation of protein localization to cell periphery", "Positive regulation of protein localization to cell surface", "Positive regulation of protein localization to centrosome", "Positive regulation of protein localization to cilium", "Positive regulation of protein localization to early endosome", "Positive regulation of protein localization to membrane", "Positive regulation of protein localization to nucleus", "Positive regulation of protein maturation", "Positive regulation of protein metabolic process", "Positive regulation of protein modification by small protein conjugation or removal", "Positive regulation of protein modification process", "Positive regulation of protein monoubiquitination", "Positive regulation of protein neddylation", "Positive regulation of protein phosphorylation", "Positive regulation of protein polymerization", "Positive regulation of protein polyubiquitination", "Positive regulation of protein secretion", "Positive regulation of protein serine threonine kinase activity", "Positive regulation of protein sumoylation", "Positive regulation of protein targeting to membrane", "Positive regulation of protein tyrosine kinase activity", "Positive regulation of proteolysis", "Positive regulation of proteolysis involved in cellular protein catabolic process", "Positive regulation of pseudopodium assembly", "Positive regulation of reactive oxygen species biosynthetic process", "Positive regulation of reactive oxygen species metabolic process", "Positive regulation of receptor binding", "Positive regulation of receptor catabolic process", "Positive regulation of receptor clustering", "Positive regulation of receptor internalization", "Positive regulation of receptor mediated endocytosis", "Positive regulation of receptor recycling", "Positive regulation of receptor signaling pathway via stat", "Positive regulation of regulated secretory pathway", "Positive regulation of release of cytochrome c from mitochondria", "Positive regulation of release of sequestered calcium ion into cytosol", "Positive regulation of renal sodium excretion", "Positive regulation of reproductive process", "Positive regulation of respiratory burst", "Positive regulation of response to biotic stimulus", "Positive regulation of response to cytokine stimulus", "Positive regulation of response to dna damage stimulus", "Positive regulation of response to endoplasmic reticulum stress", "Positive regulation of response to external stimulus", "Positive regulation of response to interferon gamma", "Positive regulation of response to oxidative stress", "Positive regulation of response to reactive oxygen species", "Positive regulation of response to tumor cell", "Positive regulation of response to wounding", "Positive regulation of retinoic acid receptor signaling pathway", "Positive regulation of rho protein signal transduction", "Positive regulation of rig i signaling pathway", "Positive regulation of rna binding", "Positive regulation of rna export from nucleus", "Positive regulation of rna metabolic process", "Positive regulation of rna polymerase ii transcription preinitiation complex assembly", "Positive regulation of rna splicing", "Positive regulation of rrna processing", "Positive regulation of ruffle assembly", "Positive regulation of ryanodine sensitive calcium release channel activity", "Positive regulation of secondary metabolite biosynthetic process", "Positive regulation of secretion", "Positive regulation of sequestering of calcium ion", "Positive regulation of sequestering of triglyceride", "Positive regulation of signal transduction by p53 class mediator", "Positive regulation of signaling", "Positive regulation of signaling receptor activity", "Positive regulation of sister chromatid cohesion", "Positive regulation of skeletal muscle tissue development", "Positive regulation of smad protein signal transduction", "Positive regulation of small gtpase mediated signal transduction", "Positive regulation of small molecule metabolic process", "Positive regulation of smooth muscle cell apoptotic process", "Positive regulation of smooth muscle cell differentiation", "Positive regulation of smooth muscle cell migration", "Positive regulation of smooth muscle cell proliferation", "Positive regulation of smooth muscle contraction", "Positive regulation of smoothened signaling pathway", "Positive regulation of sodium ion transmembrane transport", "Positive regulation of sodium ion transmembrane transporter activity", "Positive regulation of sodium ion transport", "Positive regulation of sphingolipid biosynthetic process", "Positive regulation of spindle assembly", "Positive regulation of sprouting angiogenesis", "Positive regulation of stem cell differentiation", "Positive regulation of stem cell population maintenance", "Positive regulation of stem cell proliferation", "Positive regulation of steroid biosynthetic process", "Positive regulation of steroid hormone biosynthetic process", "Positive regulation of steroid metabolic process", "Positive regulation of sterol transport", "Positive regulation of stress activated protein kinase signaling cascade", "Positive regulation of stress fiber assembly", "Positive regulation of striated muscle cell apoptotic process", "Positive regulation of striated muscle cell differentiation", "Positive regulation of striated muscle contraction", "Positive regulation of substrate adhesion dependent cell spreading", "Positive regulation of supramolecular fiber organization", "Positive regulation of synapse assembly", "Positive regulation of synapse maturation", "Positive regulation of synaptic plasticity", "Positive regulation of synaptic transmission", "Positive regulation of synaptic transmission gabaergic", "Positive regulation of synaptic transmission glutamatergic", "Positive regulation of synaptic vesicle endocytosis", "Positive regulation of synaptic vesicle exocytosis", "Positive regulation of synaptic vesicle recycling", "Positive regulation of syncytium formation by plasma membrane fusion", "Positive regulation of systemic arterial blood pressure", "Positive regulation of t cell apoptotic process", "Positive regulation of t cell cytokine production", "Positive regulation of t cell differentiation in thymus", "Positive regulation of t cell mediated cytotoxicity", "Positive regulation of t cell mediated immune response to tumor cell", "Positive regulation of t cell mediated immunity", "Positive regulation of t cell migration", "Positive regulation of t cell proliferation", "Positive regulation of t cell receptor signaling pathway", "Positive regulation of t cell tolerance induction", "Positive regulation of t helper 1 cell differentiation", "Positive regulation of t helper cell differentiation", "Positive regulation of tau protein kinase activity", "Positive regulation of telomerase activity", "Positive regulation of telomerase rna localization to cajal body", "Positive regulation of telomere capping", "Positive regulation of telomere maintenance", "Positive regulation of telomere maintenance via telomere lengthening", "Positive regulation of tissue remodeling", "Positive regulation of tolerance induction", "Positive regulation of toll like receptor 3 signaling pathway", "Positive regulation of toll like receptor 9 signaling pathway", "Positive regulation of toll like receptor signaling pathway", "Positive regulation of tor signaling", "Positive regulation of torc1 signaling", "Positive regulation of transcription by rna polymerase i", "Positive regulation of transcription by rna polymerase ii", "Positive regulation of transcription by rna polymerase iii", "Positive regulation of transcription elongation from rna polymerase ii promoter", "Positive regulation of transcription from rna polymerase ii promoter in response to endoplasmic reticulum stress", "Positive regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Positive regulation of transcription from rna polymerase ii promoter in response to stress", "Positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus", "Positive regulation of transcription of notch receptor target", "Positive regulation of transcription of nucleolar large rrna by rna polymerase i", "Positive regulation of transcription regulatory region dna binding", "Positive regulation of transferase activity", "Positive regulation of transforming growth factor beta production", "Positive regulation of transforming growth factor beta1 production", "Positive regulation of translation", "Positive regulation of translation in response to endoplasmic reticulum stress", "Positive regulation of translation in response to stress", "Positive regulation of translational initiation", "Positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Positive regulation of transmembrane transport", "Positive regulation of transmission of nerve impulse", "Positive regulation of transport", "Positive regulation of transporter activity", "Positive regulation of triglyceride biosynthetic process", "Positive regulation of triglyceride metabolic process", "Positive regulation of trophoblast cell migration", "Positive regulation of tumor necrosis factor mediated signaling pathway", "Positive regulation of tumor necrosis factor superfamily cytokine production", "Positive regulation of type i interferon mediated signaling pathway", "Positive regulation of type i interferon production", "Positive regulation of tyrosine phosphorylation of stat protein", "Positive regulation of ubiquitin dependent protein catabolic process", "Positive regulation of ubiquitin protein ligase activity", "Positive regulation of ubiquitin protein transferase activity", "Positive regulation of unsaturated fatty acid biosynthetic process", "Positive regulation of urine volume", "Positive regulation of vacuole organization", "Positive regulation of vascular associated smooth muscle cell apoptotic process", "Positive regulation of vascular associated smooth muscle cell differentiation", "Positive regulation of vascular associated smooth muscle cell migration", "Positive regulation of vascular associated smooth muscle cell proliferation", "Positive regulation of vascular endothelial cell proliferation", "Positive regulation of vascular endothelial growth factor production", "Positive regulation of vascular endothelial growth factor signaling pathway", "Positive regulation of vascular permeability", "Positive regulation of vasculature development", "Positive regulation of vasculogenesis", "Positive regulation of vasoconstriction", "Positive regulation of vesicle fusion", "Positive regulation of viral genome replication", "Positive regulation of viral life cycle", "Positive regulation of viral process", "Positive regulation of vitamin d receptor signaling pathway", "Positive regulation of voltage gated calcium channel activity", "Positive regulation of wnt signaling pathway", "Positive regulation of wound healing", "Positive regulation of wound healing spreading of epidermal cells", "Positive t cell selection", "Post anal tail morphogenesis", "Post chaperonin tubulin folding pathway", "Post embryonic animal morphogenesis", "Post embryonic animal organ development", "Post embryonic animal organ morphogenesis", "Post embryonic camera type eye development", "Post embryonic development", "Post embryonic eye morphogenesis", "Post golgi vesicle mediated transport", "Post translational protein modification", "Postreplication repair", "Postsynapse assembly", "Postsynapse organization", "Postsynapse to nucleus signaling pathway", "Postsynaptic actin cytoskeleton organization", "Postsynaptic cytoskeleton organization", "Postsynaptic density protein 95 clustering", "Postsynaptic membrane assembly", "Postsynaptic membrane organization", "Postsynaptic modulation of chemical synaptic transmission", "Postsynaptic neurotransmitter receptor internalization", "Postsynaptic signal transduction", "Postsynaptic specialization organization", "Posttranscriptional regulation of gene expression", "Posttranslational protein targeting to endoplasmic reticulum membrane", "Posttranslational protein targeting to membrane translocation", "Potassium ion homeostasis", "Potassium ion import across plasma membrane", "Potassium ion transport", "Pre mirna processing", "Preassembly of gpi anchor in er membrane", "Prenylation", "Prepulse inhibition", "Presynapse organization", "Presynaptic active zone organization", "Presynaptic endocytosis", "Presynaptic modulation of chemical synaptic transmission", "Prevention of polyspermy", "Primary alcohol biosynthetic process", "Primary alcohol catabolic process", "Primary alcohol metabolic process", "Primary amino compound biosynthetic process", "Primary amino compound metabolic process", "Primary mirna processing", "Primitive hemopoiesis", "Pro b cell differentiation", "Process utilizing autophagic mechanism", "Production of molecular mediator involved in inflammatory response", "Production of molecular mediator of immune response", "Production of sirna involved in rna interference", "Progesterone receptor signaling pathway", "Programmed cell death", "Programmed cell death in response to reactive oxygen species", "Programmed cell death involved in cell development", "Programmed necrotic cell death", "Prolactin secretion", "Proline metabolic process", "Proline transport", "Pronephros development", "Proprioception", "Prostaglandin transport", "Prostanoid biosynthetic process", "Prostanoid metabolic process", "Prostate gland development", "Prostate gland growth", "Prostate gland morphogenesis", "Prostate glandular acinus development", "Prostate glandular acinus morphogenesis", "Prosthetic group metabolic process", "Proteasomal protein catabolic process", "Proteasome assembly", "Proteasome mediated ubiquitin dependent protein catabolic process", "Protection from natural killer cell mediated cytotoxicity", "Protection from non homologous end joining at telomere", "Protein acetylation", "Protein activation cascade", "Protein acylation", "Protein adp ribosylation", "Protein auto adp ribosylation", "Protein autophosphorylation", "Protein autoprocessing", "Protein autoubiquitination", "Protein catabolic process", "Protein catabolic process in the vacuole", "Protein complex oligomerization", "Protein containing complex disassembly", "Protein containing complex localization", "Protein containing complex organization", "Protein containing complex remodeling", "Protein de adp ribosylation", "Protein deglycosylation", "Protein demannosylation", "Protein demethylation", "Protein deneddylation", "Protein depalmitoylation", "Protein dephosphorylation", "Protein depolymerization", "Protein destabilization", "Protein desumoylation", "Protein deubiquitination involved in ubiquitin dependent protein catabolic process", "Protein dna complex assembly", "Protein dna complex disassembly", "Protein dna complex subunit organization", "Protein dna covalent cross linking repair", "Protein exit from endoplasmic reticulum", "Protein export from nucleus", "Protein folding", "Protein folding in endoplasmic reticulum", "Protein geranylgeranylation", "Protein heterooligomerization", "Protein heterotetramerization", "Protein hexamerization", "Protein homooligomerization", "Protein homotetramerization", "Protein hydroxylation", "Protein import", "Protein import into mitochondrial matrix", "Protein import into peroxisome matrix", "Protein import into peroxisome membrane", "Protein insertion into er membrane", "Protein insertion into er membrane by stop transfer membrane anchor sequence", "Protein insertion into membrane", "Protein insertion into mitochondrial inner membrane", "Protein insertion into mitochondrial membrane involved in apoptotic signaling pathway", "Protein k11 linked deubiquitination", "Protein k11 linked ubiquitination", "Protein k27 linked ubiquitination", "Protein k29 linked ubiquitination", "Protein k48 linked deubiquitination", "Protein k48 linked ubiquitination", "Protein k6 linked ubiquitination", "Protein k63 linked deubiquitination", "Protein k63 linked ubiquitination", "Protein kinase a signaling", "Protein kinase b signaling", "Protein kinase c signaling", "Protein lipid complex assembly", "Protein lipid complex subunit organization", "Protein localization to adherens junction", "Protein localization to axon", "Protein localization to basolateral plasma membrane", "Protein localization to cell cell junction", "Protein localization to cell cortex", "Protein localization to cell junction", "Protein localization to cell periphery", "Protein localization to cell surface", "Protein localization to chromatin", "Protein localization to chromosome", "Protein localization to chromosome centromeric region", "Protein localization to chromosome telomeric region", "Protein localization to ciliary membrane", "Protein localization to cilium", "Protein localization to condensed chromosome", "Protein localization to cytoplasmic stress granule", "Protein localization to cytoskeleton", "Protein localization to early endosome", "Protein localization to endoplasmic reticulum", "Protein localization to endoplasmic reticulum exit site", "Protein localization to endosome", "Protein localization to extracellular region", "Protein localization to golgi apparatus", "Protein localization to lysosome", "Protein localization to membrane raft", "Protein localization to microtubule", "Protein localization to microtubule end", "Protein localization to microtubule organizing center", "Protein localization to mitochondrion", "Protein localization to nuclear body", "Protein localization to nuclear envelope", "Protein localization to nucleolus", "Protein localization to nucleoplasm", "Protein localization to nucleus", "Protein localization to organelle", "Protein localization to perinuclear region of cytoplasm", "Protein localization to phagophore assembly site", "Protein localization to plasma membrane", "Protein localization to postsynapse", "Protein localization to presynapse", "Protein localization to synapse", "Protein localization to vacuole", "Protein mannosylation", "Protein maturation", "Protein maturation by 4fe 4s cluster transfer", "Protein maturation by iron sulfur cluster transfer", "Protein maturation by protein folding", "Protein methylation", "Protein modification by small protein conjugation", "Protein modification by small protein conjugation or removal", "Protein modification by small protein removal", "Protein monoubiquitination", "Protein n linked glycosylation", "Protein neddylation", "Protein nitrosylation", "Protein o linked fucosylation", "Protein o linked glycosylation", "Protein o linked glycosylation via serine", "Protein o linked glycosylation via threonine", "Protein o linked mannosylation", "Protein oxidation", "Protein peptidyl prolyl isomerization", "Protein poly adp ribosylation", "Protein polyglutamylation", "Protein polymerization", "Protein polyubiquitination", "Protein polyufmylation", "Protein processing", "Protein processing involved in protein targeting to mitochondrion", "Protein quality control for misfolded or incompletely synthesized proteins", "Protein refolding", "Protein repair", "Protein retention in er lumen", "Protein retention in golgi apparatus", "Protein stabilization", "Protein sumoylation", "Protein targeting", "Protein targeting to lysosome", "Protein targeting to membrane", "Protein targeting to mitochondrion", "Protein targeting to peroxisome", "Protein targeting to vacuole", "Protein tetramerization", "Protein transmembrane import into intracellular organelle", "Protein transmembrane transport", "Protein transport along microtubule", "Protein transport to vacuole involved in ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Protein transport within lipid bilayer", "Protein trimerization", "Protein ufmylation", "Proteoglycan biosynthetic process", "Proteoglycan metabolic process", "Proteolysis", "Proton transmembrane transport", "Proton transporting two sector atpase complex assembly", "Proton transporting v type atpase complex assembly", "Protoporphyrinogen ix biosynthetic process", "Protoporphyrinogen ix metabolic process", "Proximal distal pattern formation", "Proximal distal pattern formation involved in nephron development", "Proximal tubule development", "Pseudopodium organization", "Pseudouridine synthesis", "Pteridine containing compound biosynthetic process", "Pteridine containing compound metabolic process", "Pulmonary valve development", "Pulmonary valve morphogenesis", "Purine containing compound biosynthetic process", "Purine containing compound catabolic process", "Purine containing compound metabolic process", "Purine containing compound salvage", "Purine containing compound transmembrane transport", "Purine deoxyribonucleoside metabolic process", "Purine deoxyribonucleoside monophosphate catabolic process", "Purine deoxyribonucleoside monophosphate metabolic process", "Purine deoxyribonucleoside triphosphate metabolic process", "Purine deoxyribonucleotide biosynthetic process", "Purine deoxyribonucleotide catabolic process", "Purine deoxyribonucleotide metabolic process", "Purine nucleobase biosynthetic process", "Purine nucleobase metabolic process", "Purine nucleoside biosynthetic process", "Purine nucleoside catabolic process", "Purine nucleoside diphosphate biosynthetic process", "Purine nucleoside diphosphate catabolic process", "Purine nucleoside metabolic process", "Purine nucleoside monophosphate biosynthetic process", "Purine nucleoside monophosphate catabolic process", "Purine nucleoside monophosphate metabolic process", "Purine nucleoside triphosphate catabolic process", "Purine nucleotide catabolic process", "Purine nucleotide salvage", "Purine nucleotide transport", "Purine ribonucleoside catabolic process", "Purine ribonucleoside metabolic process", "Purine ribonucleoside salvage", "Purine ribonucleotide salvage", "Purinergic nucleotide receptor signaling pathway", "Putrescine metabolic process", "Pyramidal neuron development", "Pyramidal neuron differentiation", "Pyridine containing compound biosynthetic process", "Pyridine containing compound catabolic process", "Pyridine containing compound metabolic process", "Pyridine nucleotide biosynthetic process", "Pyridine nucleotide metabolic process", "Pyrimidine containing compound biosynthetic process", "Pyrimidine containing compound catabolic process", "Pyrimidine containing compound metabolic process", "Pyrimidine containing compound salvage", "Pyrimidine containing compound transmembrane transport", "Pyrimidine deoxyribonucleoside metabolic process", "Pyrimidine deoxyribonucleoside monophosphate biosynthetic process", "Pyrimidine deoxyribonucleoside monophosphate metabolic process", "Pyrimidine deoxyribonucleoside triphosphate metabolic process", "Pyrimidine deoxyribonucleotide biosynthetic process", "Pyrimidine deoxyribonucleotide metabolic process", "Pyrimidine dimer repair", "Pyrimidine nucleobase biosynthetic process", "Pyrimidine nucleobase catabolic process", "Pyrimidine nucleobase metabolic process", "Pyrimidine nucleoside catabolic process", "Pyrimidine nucleoside diphosphate biosynthetic process", "Pyrimidine nucleoside diphosphate metabolic process", "Pyrimidine nucleoside metabolic process", "Pyrimidine nucleoside monophosphate biosynthetic process", "Pyrimidine nucleoside monophosphate metabolic process", "Pyrimidine nucleoside triphosphate biosynthetic process", "Pyrimidine nucleoside triphosphate metabolic process", "Pyrimidine nucleotide catabolic process", "Pyrimidine nucleotide metabolic process", "Pyrimidine ribonucleoside diphosphate metabolic process", "Pyrimidine ribonucleoside monophosphate metabolic process", "Pyrimidine ribonucleoside triphosphate biosynthetic process", "Pyrimidine ribonucleoside triphosphate metabolic process", "Pyrimidine ribonucleotide biosynthetic process", "Pyrimidine ribonucleotide metabolic process", "Pyroptosis", "Pyruvate metabolic process", "Pyruvate transmembrane transport", "Pyruvate transport", "Quaternary ammonium group transport", "Quinone metabolic process", "R loop disassembly", "Rab protein signal transduction", "Rac protein signal transduction", "Radial glial cell differentiation", "Rap protein signal transduction", "Ras protein signal transduction", "Reactive nitrogen species metabolic process", "Reactive oxygen species biosynthetic process", "Reactive oxygen species metabolic process", "Receptor catabolic process", "Receptor clustering", "Receptor diffusion trapping", "Receptor internalization", "Receptor localization to synapse", "Receptor mediated endocytosis", "Receptor mediated endocytosis involved in cholesterol transport", "Receptor metabolic process", "Receptor recycling", "Receptor signaling pathway via stat", "Receptor transactivation", "Recognition of apoptotic cell", "Recombinational repair", "Reelin mediated signaling pathway", "Reflex", "Regeneration", "Regionalization", "Regulated exocytosis", "Regulation by virus of viral protein levels in host cell", "Regulation of 3 utr mediated mrna stabilization", "Regulation of acrosome reaction", "Regulation of actin cytoskeleton reorganization", "Regulation of actin filament based movement", "Regulation of actin filament based process", "Regulation of actin filament bundle assembly", "Regulation of actin filament length", "Regulation of actin filament organization", "Regulation of actin nucleation", "Regulation of action potential", "Regulation of activin receptor signaling pathway", "Regulation of actomyosin structure organization", "Regulation of acute inflammatory response", "Regulation of acute inflammatory response to antigenic stimulus", "Regulation of acyl coa biosynthetic process", "Regulation of adaptive immune response", "Regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Regulation of adenylate cyclase activity", "Regulation of adherens junction organization", "Regulation of adipose tissue development", "Regulation of aerobic respiration", "Regulation of alcohol biosynthetic process", "Regulation of alpha beta t cell activation", "Regulation of alpha beta t cell differentiation", "Regulation of alternative mrna splicing via spliceosome", "Regulation of amino acid transmembrane transport", "Regulation of amino acid transport", "Regulation of amyloid beta clearance", "Regulation of amyloid fibril formation", "Regulation of amyloid precursor protein catabolic process", "Regulation of anaphase promoting complex dependent catabolic process", "Regulation of anatomical structure morphogenesis", "Regulation of anatomical structure size", "Regulation of androgen receptor signaling pathway", "Regulation of angiotensin levels in blood", "Regulation of animal organ formation", "Regulation of animal organ morphogenesis", "Regulation of anion channel activity", "Regulation of anion transmembrane transport", "Regulation of anion transport", "Regulation of anoikis", "Regulation of antifungal innate immune response", "Regulation of antigen processing and presentation", "Regulation of antigen receptor mediated signaling pathway", "Regulation of apoptotic cell clearance", "Regulation of apoptotic dna fragmentation", "Regulation of apoptotic process involved in development", "Regulation of apoptotic signaling pathway", "Regulation of appetite", "Regulation of arachidonic acid secretion", "Regulation of arp2 3 complex mediated actin nucleation", "Regulation of aspartic type endopeptidase activity involved in amyloid precursor protein catabolic process", "Regulation of aspartic type peptidase activity", "Regulation of astrocyte activation", "Regulation of astrocyte differentiation", "Regulation of atp biosynthetic process", "Regulation of atp dependent activity", "Regulation of atp metabolic process", "Regulation of atpase coupled calcium transmembrane transporter activity", "Regulation of atrial cardiac muscle cell membrane repolarization", "Regulation of attachment of spindle microtubules to kinetochore", "Regulation of autophagosome maturation", "Regulation of autophagy", "Regulation of autophagy of mitochondrion", "Regulation of autophagy of mitochondrion in response to mitochondrial depolarization", "Regulation of axon diameter", "Regulation of axon guidance", "Regulation of axonogenesis", "Regulation of b cell activation", "Regulation of b cell apoptotic process", "Regulation of b cell differentiation", "Regulation of b cell mediated immunity", "Regulation of b cell proliferation", "Regulation of barbed end actin filament capping", "Regulation of behavior", "Regulation of bicellular tight junction assembly", "Regulation of bile acid biosynthetic process", "Regulation of bile acid metabolic process", "Regulation of bile acid secretion", "Regulation of binding", "Regulation of biological process involved in symbiotic interaction", "Regulation of biomineralization", "Regulation of blood brain barrier permeability", "Regulation of blood circulation", "Regulation of blood pressure", "Regulation of bmp signaling pathway", "Regulation of body fluid levels", "Regulation of bone mineralization", "Regulation of bone remodeling", "Regulation of bone resorption", "Regulation of branching involved in lung morphogenesis", "Regulation of branching involved in prostate gland morphogenesis", "Regulation of branching involved in ureteric bud morphogenesis", "Regulation of branching morphogenesis of a nerve", "Regulation of brown fat cell differentiation", "Regulation of calcidiol 1 monooxygenase activity", "Regulation of calcineurin mediated signaling", "Regulation of calcium ion dependent exocytosis", "Regulation of calcium ion export across plasma membrane", "Regulation of calcium ion import", "Regulation of calcium ion transmembrane transport", "Regulation of calcium ion transmembrane transporter activity", "Regulation of calcium ion transport", "Regulation of calcium ion transport into cytosol", "Regulation of calcium mediated signaling", "Regulation of camp dependent protein kinase activity", "Regulation of camp mediated signaling", "Regulation of canonical wnt signaling pathway", "Regulation of carbohydrate biosynthetic process", "Regulation of carbohydrate catabolic process", "Regulation of carbohydrate metabolic process", "Regulation of cardiac conduction", "Regulation of cardiac muscle adaptation", "Regulation of cardiac muscle cell action potential", "Regulation of cardiac muscle cell action potential involved in regulation of contraction", "Regulation of cardiac muscle cell membrane potential", "Regulation of cardiac muscle cell membrane repolarization", "Regulation of cardiac muscle cell proliferation", "Regulation of cardiac muscle contraction", "Regulation of cardiac muscle contraction by calcium ion signaling", "Regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion", "Regulation of cardioblast differentiation", "Regulation of cardiocyte differentiation", "Regulation of cartilage development", "Regulation of catabolic process", "Regulation of catecholamine metabolic process", "Regulation of cation channel activity", "Regulation of cation transmembrane transport", "Regulation of cd4 positive alpha beta t cell activation", "Regulation of cd4 positive alpha beta t cell differentiation", "Regulation of cd40 signaling pathway", "Regulation of cd8 positive alpha beta t cell activation", "Regulation of cell activation", "Regulation of cell adhesion", "Regulation of cell adhesion mediated by integrin", "Regulation of cell aging", "Regulation of cell cell adhesion", "Regulation of cell cell adhesion mediated by cadherin", "Regulation of cell cell adhesion mediated by integrin", "Regulation of cell communication by electrical coupling", "Regulation of cell communication by electrical coupling involved in cardiac conduction", "Regulation of cell cycle", "Regulation of cell cycle checkpoint", "Regulation of cell cycle g1 s phase transition", "Regulation of cell cycle g2 m phase transition", "Regulation of cell cycle phase transition", "Regulation of cell cycle process", "Regulation of cell death", "Regulation of cell development", "Regulation of cell differentiation", "Regulation of cell division", "Regulation of cell growth involved in cardiac muscle cell development", "Regulation of cell junction assembly", "Regulation of cell killing", "Regulation of cell matrix adhesion", "Regulation of cell maturation", "Regulation of cell migration involved in sprouting angiogenesis", "Regulation of cell morphogenesis", "Regulation of cell morphogenesis involved in differentiation", "Regulation of cell population proliferation", "Regulation of cell projection assembly", "Regulation of cell projection organization", "Regulation of cell projection size", "Regulation of cell shape", "Regulation of cell size", "Regulation of cell substrate adhesion", "Regulation of cell substrate junction organization", "Regulation of cellular amide metabolic process", "Regulation of cellular amine metabolic process", "Regulation of cellular amino acid metabolic process", "Regulation of cellular carbohydrate catabolic process", "Regulation of cellular carbohydrate metabolic process", "Regulation of cellular component biogenesis", "Regulation of cellular component movement", "Regulation of cellular component size", "Regulation of cellular extravasation", "Regulation of cellular ketone metabolic process", "Regulation of cellular localization", "Regulation of cellular macromolecule biosynthetic process", "Regulation of cellular ph", "Regulation of cellular ph reduction", "Regulation of cellular protein catabolic process", "Regulation of cellular respiration", "Regulation of cellular response to growth factor stimulus", "Regulation of cellular response to heat", "Regulation of cellular response to hypoxia", "Regulation of cellular response to insulin stimulus", "Regulation of cellular response to osmotic stress", "Regulation of cellular response to stress", "Regulation of cellular response to transforming growth factor beta stimulus", "Regulation of cellular response to vascular endothelial growth factor stimulus", "Regulation of centriole replication", "Regulation of centrosome cycle", "Regulation of chaperone mediated autophagy", "Regulation of chemokine mediated signaling pathway", "Regulation of chemotaxis", "Regulation of chloride transport", "Regulation of cholesterol biosynthetic process", "Regulation of cholesterol efflux", "Regulation of cholesterol esterification", "Regulation of cholesterol metabolic process", "Regulation of chondrocyte differentiation", "Regulation of chromatin assembly", "Regulation of chromatin assembly or disassembly", "Regulation of chromatin binding", "Regulation of chromatin organization", "Regulation of chromosome condensation", "Regulation of chromosome organization", "Regulation of chromosome segregation", "Regulation of chromosome separation", "Regulation of cilium assembly", "Regulation of cilium beat frequency", "Regulation of cilium beat frequency involved in ciliary motility", "Regulation of cilium dependent cell motility", "Regulation of cilium movement", "Regulation of circadian rhythm", "Regulation of clathrin dependent endocytosis", "Regulation of coagulation", "Regulation of collagen fibril organization", "Regulation of collagen metabolic process", "Regulation of collateral sprouting", "Regulation of complement activation", "Regulation of complement dependent cytotoxicity", "Regulation of connective tissue replacement", "Regulation of core promoter binding", "Regulation of corticotropin secretion", "Regulation of cyclase activity", "Regulation of cyclic nucleotide phosphodiesterase activity", "Regulation of cyclin dependent protein kinase activity", "Regulation of cysteine type endopeptidase activity", "Regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Regulation of cysteine type endopeptidase activity involved in execution phase of apoptosis", "Regulation of cytokinesis", "Regulation of cytoplasmic mrna processing body assembly", "Regulation of cytoplasmic translation", "Regulation of cytoplasmic translational elongation", "Regulation of cytoplasmic translational initiation", "Regulation of cytoplasmic transport", "Regulation of cytoskeleton organization", "Regulation of cytosolic calcium ion concentration", "Regulation of deacetylase activity", "Regulation of defense response", "Regulation of defense response to fungus", "Regulation of defense response to virus", "Regulation of defense response to virus by host", "Regulation of delayed rectifier potassium channel activity", "Regulation of dendrite development", "Regulation of dendrite extension", "Regulation of dendrite morphogenesis", "Regulation of dendritic cell chemotaxis", "Regulation of dendritic cell differentiation", "Regulation of dendritic spine development", "Regulation of dendritic spine maintenance", "Regulation of dendritic spine morphogenesis", "Regulation of deoxyribonuclease activity", "Regulation of dephosphorylation", "Regulation of developmental growth", "Regulation of digestive system process", "Regulation of dna binding", "Regulation of dna binding transcription factor activity", "Regulation of dna biosynthetic process", "Regulation of dna catabolic process", "Regulation of dna damage checkpoint", "Regulation of dna damage response signal transduction by p53 class mediator", "Regulation of dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator", "Regulation of dna demethylation", "Regulation of dna dependent dna replication", "Regulation of dna dependent dna replication initiation", "Regulation of dna directed dna polymerase activity", "Regulation of dna duplex unwinding", "Regulation of dna helicase activity", "Regulation of dna ligation", "Regulation of dna metabolic process", "Regulation of dna methylation", "Regulation of dna methylation dependent heterochromatin assembly", "Regulation of dna primase activity", "Regulation of dna recombination", "Regulation of dna repair", "Regulation of dna replication", "Regulation of dna strand elongation", "Regulation of dna templated transcription elongation", "Regulation of dna templated transcription in response to stress", "Regulation of dna templated transcription initiation", "Regulation of dna topoisomerase atp hydrolyzing activity", "Regulation of dopamine receptor signaling pathway", "Regulation of dopaminergic neuron differentiation", "Regulation of double strand break repair", "Regulation of double strand break repair via homologous recombination", "Regulation of double strand break repair via nonhomologous end joining", "Regulation of early endosome to late endosome transport", "Regulation of electron transfer activity", "Regulation of embryonic development", "Regulation of endocrine process", "Regulation of endocytic recycling", "Regulation of endocytosis", "Regulation of endodeoxyribonuclease activity", "Regulation of endodermal cell differentiation", "Regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Regulation of endoplasmic reticulum tubular network organization", "Regulation of endoplasmic reticulum unfolded protein response", "Regulation of endothelial cell chemotaxis", "Regulation of endothelial cell development", "Regulation of endothelial cell differentiation", "Regulation of endothelial cell migration", "Regulation of entry of bacterium into host cell", "Regulation of epidermal growth factor activated receptor activity", "Regulation of epidermis development", "Regulation of epithelial cell apoptotic process", "Regulation of epithelial cell differentiation", "Regulation of epithelial cell differentiation involved in kidney development", "Regulation of epithelial cell migration", "Regulation of epithelial cell proliferation involved in lung morphogenesis", "Regulation of epithelial to mesenchymal transition", "Regulation of er associated ubiquitin dependent protein catabolic process", "Regulation of er to golgi vesicle mediated transport", "Regulation of erad pathway", "Regulation of erbb signaling pathway", "Regulation of erythrocyte differentiation", "Regulation of establishment of planar polarity", "Regulation of establishment of protein localization", "Regulation of establishment of protein localization to chromosome", "Regulation of establishment of protein localization to mitochondrion", "Regulation of establishment or maintenance of cell polarity", "Regulation of excretion", "Regulation of execution phase of apoptosis", "Regulation of exit from mitosis", "Regulation of exocytosis", "Regulation of exosomal secretion", "Regulation of extent of cell growth", "Regulation of extracellular matrix assembly", "Regulation of extracellular matrix constituent secretion", "Regulation of extracellular matrix disassembly", "Regulation of extracellular matrix organization", "Regulation of extrinsic apoptotic signaling pathway", "Regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Regulation of fat cell differentiation", "Regulation of fat cell proliferation", "Regulation of fatty acid beta oxidation", "Regulation of fatty acid biosynthetic process", "Regulation of fatty acid metabolic process", "Regulation of fatty acid oxidation", "Regulation of fatty acid transport", "Regulation of fc gamma receptor signaling pathway involved in phagocytosis", "Regulation of fc receptor mediated stimulatory signaling pathway", "Regulation of feeding behavior", "Regulation of fertilization", "Regulation of fibroblast growth factor receptor signaling pathway", "Regulation of fibroblast migration", "Regulation of filopodium assembly", "Regulation of focal adhesion disassembly", "Regulation of g protein coupled receptor signaling pathway", "Regulation of g0 to g1 transition", "Regulation of gastrulation", "Regulation of gene expression by genomic imprinting", "Regulation of gene expression epigenetic", "Regulation of gene silencing by rna", "Regulation of generation of precursor metabolites and energy", "Regulation of genetic imprinting", "Regulation of germ cell proliferation", "Regulation of germinal center formation", "Regulation of glial cell apoptotic process", "Regulation of glial cell differentiation", "Regulation of glial cell migration", "Regulation of glial cell proliferation", "Regulation of gliogenesis", "Regulation of glucagon secretion", "Regulation of glucan biosynthetic process", "Regulation of glucocorticoid biosynthetic process", "Regulation of glucocorticoid metabolic process", "Regulation of glucocorticoid receptor signaling pathway", "Regulation of glucocorticoid secretion", "Regulation of gluconeogenesis", "Regulation of glucose import", "Regulation of glucose metabolic process", "Regulation of glucose transmembrane transport", "Regulation of glucosylceramidase activity", "Regulation of glutamate receptor clustering", "Regulation of glutamate secretion", "Regulation of glycogen catabolic process", "Regulation of glycogen metabolic process", "Regulation of glycogen starch synthase activity", "Regulation of glycolytic process", "Regulation of glycoprotein metabolic process", "Regulation of golgi organization", "Regulation of golgi to plasma membrane protein transport", "Regulation of gonad development", "Regulation of granulocyte chemotaxis", "Regulation of granulocyte differentiation", "Regulation of growth", "Regulation of gtp binding", "Regulation of gtpase activity", "Regulation of guanyl nucleotide exchange factor activity", "Regulation of hair cycle", "Regulation of hair follicle development", "Regulation of heart contraction", "Regulation of heart growth", "Regulation of heart rate", "Regulation of heart rate by cardiac conduction", "Regulation of heart rate by chemical signal", "Regulation of helicase activity", "Regulation of hematopoietic progenitor cell differentiation", "Regulation of hematopoietic stem cell differentiation", "Regulation of hematopoietic stem cell proliferation", "Regulation of hemoglobin biosynthetic process", "Regulation of hemopoiesis", "Regulation of hepatic stellate cell activation", "Regulation of hepatocyte apoptotic process", "Regulation of hepatocyte proliferation", "Regulation of heterotypic cell cell adhesion", "Regulation of hexokinase activity", "Regulation of high voltage gated calcium channel activity", "Regulation of hippo signaling", "Regulation of histamine secretion by mast cell", "Regulation of histone deacetylase activity", "Regulation of histone deacetylation", "Regulation of histone h2b ubiquitination", "Regulation of histone h3 k14 acetylation", "Regulation of histone h3 k27 methylation", "Regulation of histone h3 k36 methylation", "Regulation of histone h3 k4 methylation", "Regulation of histone h3 k9 methylation", "Regulation of histone h3 k9 trimethylation", "Regulation of histone h4 acetylation", "Regulation of histone h4 k16 acetylation", "Regulation of histone methylation", "Regulation of histone modification", "Regulation of histone phosphorylation", "Regulation of histone ubiquitination", "Regulation of homophilic cell adhesion", "Regulation of homotypic cell cell adhesion", "Regulation of hormone biosynthetic process", "Regulation of hormone levels", "Regulation of hormone metabolic process", "Regulation of hormone secretion", "Regulation of humoral immune response", "Regulation of hyaluronan biosynthetic process", "Regulation of hydrogen peroxide biosynthetic process", "Regulation of hydrogen peroxide mediated programmed cell death", "Regulation of hydrogen peroxide metabolic process", "Regulation of hydrolase activity", "Regulation of i kappab phosphorylation", "Regulation of icosanoid secretion", "Regulation of immune effector process", "Regulation of immune response", "Regulation of immune system process", "Regulation of immunoglobulin production", "Regulation of inclusion body assembly", "Regulation of inflammatory response", "Regulation of inflammatory response to antigenic stimulus", "Regulation of innate immune response", "Regulation of inositol 1 4 5 trisphosphate sensitive calcium release channel activity", "Regulation of insulin like growth factor receptor signaling pathway", "Regulation of insulin receptor signaling pathway", "Regulation of insulin secretion", "Regulation of insulin secretion involved in cellular response to glucose stimulus", "Regulation of integrin activation", "Regulation of integrin mediated signaling pathway", "Regulation of interleukin 1 mediated signaling pathway", "Regulation of interleukin 6 mediated signaling pathway", "Regulation of intestinal absorption", "Regulation of intracellular estrogen receptor signaling pathway", "Regulation of intracellular lipid transport", "Regulation of intracellular protein transport", "Regulation of intracellular signal transduction", "Regulation of intracellular steroid hormone receptor signaling pathway", "Regulation of intracellular transport", "Regulation of intrinsic apoptotic signaling pathway", "Regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Regulation of inward rectifier potassium channel activity", "Regulation of ion transmembrane transport", "Regulation of ion transport", "Regulation of ire1 mediated unfolded protein response", "Regulation of iron ion transmembrane transport", "Regulation of iron ion transport", "Regulation of isomerase activity", "Regulation of isotype switching", "Regulation of jnk cascade", "Regulation of jun kinase activity", "Regulation of keratinocyte differentiation", "Regulation of keratinocyte migration", "Regulation of keratinocyte proliferation", "Regulation of kidney development", "Regulation of l glutamate import across plasma membrane", "Regulation of lamellipodium assembly", "Regulation of lamellipodium morphogenesis", "Regulation of lamellipodium organization", "Regulation of leukocyte adhesion to vascular endothelial cell", "Regulation of leukocyte apoptotic process", "Regulation of leukocyte chemotaxis", "Regulation of leukocyte degranulation", "Regulation of leukocyte differentiation", "Regulation of leukocyte mediated cytotoxicity", "Regulation of leukocyte mediated immunity", "Regulation of leukocyte migration", "Regulation of leukocyte proliferation", "Regulation of ligase activity", "Regulation of lipase activity", "Regulation of lipid biosynthetic process", "Regulation of lipid catabolic process", "Regulation of lipid kinase activity", "Regulation of lipid localization", "Regulation of lipid metabolic process", "Regulation of lipid storage", "Regulation of lipid transport", "Regulation of lipid transporter activity", "Regulation of lipophagy", "Regulation of lipopolysaccharide mediated signaling pathway", "Regulation of lipoprotein lipase activity", "Regulation of lipoprotein metabolic process", "Regulation of lipoprotein particle clearance", "Regulation of locomotion involved in locomotory behavior", "Regulation of long chain fatty acid import across plasma membrane", "Regulation of long chain fatty acid import into cell", "Regulation of long term neuronal synaptic plasticity", "Regulation of long term synaptic depression", "Regulation of long term synaptic potentiation", "Regulation of low density lipoprotein particle clearance", "Regulation of lyase activity", "Regulation of lymphocyte activation", "Regulation of lymphocyte apoptotic process", "Regulation of lymphocyte chemotaxis", "Regulation of lymphocyte differentiation", "Regulation of lymphocyte mediated immunity", "Regulation of lymphocyte migration", "Regulation of lymphoid progenitor cell differentiation", "Regulation of lysosomal lumen ph", "Regulation of lysosomal protein catabolic process", "Regulation of lysosome organization", "Regulation of macroautophagy", "Regulation of macrophage activation", "Regulation of macrophage apoptotic process", "Regulation of macrophage chemotaxis", "Regulation of macrophage derived foam cell differentiation", "Regulation of macrophage differentiation", "Regulation of macrophage migration", "Regulation of macrophage proliferation", "Regulation of maintenance of sister chromatid cohesion", "Regulation of male gonad development", "Regulation of mammary gland epithelial cell proliferation", "Regulation of map kinase activity", "Regulation of mast cell activation", "Regulation of mast cell activation involved in immune response", "Regulation of matrix metallopeptidase secretion", "Regulation of mda 5 signaling pathway", "Regulation of megakaryocyte differentiation", "Regulation of meiotic cell cycle", "Regulation of meiotic cell cycle phase transition", "Regulation of meiotic nuclear division", "Regulation of melanocyte differentiation", "Regulation of membrane depolarization", "Regulation of membrane depolarization during action potential", "Regulation of membrane depolarization during cardiac muscle cell action potential", "Regulation of membrane lipid distribution", "Regulation of membrane permeability", "Regulation of membrane potential", "Regulation of membrane protein ectodomain proteolysis", "Regulation of membrane repolarization", "Regulation of membrane repolarization during action potential", "Regulation of membrane repolarization during cardiac muscle cell action potential", "Regulation of membrane tubulation", "Regulation of mesenchymal cell proliferation", "Regulation of mesenchymal stem cell differentiation", "Regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis", "Regulation of mesoderm development", "Regulation of metal ion transport", "Regulation of metalloendopeptidase activity", "Regulation of metallopeptidase activity", "Regulation of metanephros development", "Regulation of metaphase plate congression", "Regulation of microglial cell activation", "Regulation of microtubule based movement", "Regulation of microtubule based process", "Regulation of microtubule binding", "Regulation of microtubule cytoskeleton organization", "Regulation of microtubule depolymerization", "Regulation of microtubule nucleation", "Regulation of microtubule polymerization", "Regulation of microtubule polymerization or depolymerization", "Regulation of microvillus assembly", "Regulation of microvillus length", "Regulation of microvillus organization", "Regulation of mirna catabolic process", "Regulation of mirna metabolic process", "Regulation of mirna transcription", "Regulation of mitochondrial atp synthesis coupled electron transport", "Regulation of mitochondrial dna replication", "Regulation of mitochondrial electron transport nadh to ubiquinone", "Regulation of mitochondrial fission", "Regulation of mitochondrial fusion", "Regulation of mitochondrial gene expression", "Regulation of mitochondrial membrane permeability", "Regulation of mitochondrial membrane permeability involved in apoptotic process", "Regulation of mitochondrial membrane potential", "Regulation of mitochondrial mrna stability", "Regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Regulation of mitochondrial rna catabolic process", "Regulation of mitochondrion organization", "Regulation of mitophagy", "Regulation of mitotic cell cycle", "Regulation of mitotic cell cycle phase transition", "Regulation of mitotic cell cycle spindle assembly checkpoint", "Regulation of mitotic centrosome separation", "Regulation of mitotic cytokinesis", "Regulation of mitotic nuclear division", "Regulation of mitotic recombination", "Regulation of mitotic sister chromatid segregation", "Regulation of mitotic spindle assembly", "Regulation of modification of postsynaptic structure", "Regulation of modification of synaptic structure", "Regulation of monocyte chemotaxis", "Regulation of monocyte differentiation", "Regulation of monocyte extravasation", "Regulation of mononuclear cell migration", "Regulation of monooxygenase activity", "Regulation of morphogenesis of a branching structure", "Regulation of morphogenesis of an epithelium", "Regulation of motor neuron apoptotic process", "Regulation of mrna 3 end processing", "Regulation of mrna binding", "Regulation of mrna catabolic process", "Regulation of mrna export from nucleus", "Regulation of mrna metabolic process", "Regulation of mrna polyadenylation", "Regulation of mrna processing", "Regulation of mrna splicing via spliceosome", "Regulation of mucus secretion", "Regulation of multicellular organism growth", "Regulation of multicellular organismal development", "Regulation of muscle adaptation", "Regulation of muscle cell differentiation", "Regulation of muscle contraction", "Regulation of muscle hypertrophy", "Regulation of muscle organ development", "Regulation of muscle system process", "Regulation of myelination", "Regulation of myeloid cell apoptotic process", "Regulation of myeloid cell differentiation", "Regulation of myeloid leukocyte differentiation", "Regulation of myeloid leukocyte mediated immunity", "Regulation of myoblast differentiation", "Regulation of myoblast fusion", "Regulation of myosin light chain phosphatase activity", "Regulation of myotube differentiation", "Regulation of nad p h oxidase activity", "Regulation of nadp metabolic process", "Regulation of natural killer cell activation", "Regulation of natural killer cell mediated immunity", "Regulation of necrotic cell death", "Regulation of nervous system development", "Regulation of nervous system process", "Regulation of neural precursor cell proliferation", "Regulation of neuroblast proliferation", "Regulation of neurogenesis", "Regulation of neuromuscular junction development", "Regulation of neuron differentiation", "Regulation of neuron migration", "Regulation of neuron projection arborization", "Regulation of neuron projection development", "Regulation of neuron projection regeneration", "Regulation of neuronal action potential", "Regulation of neuronal synaptic plasticity", "Regulation of neurotransmitter levels", "Regulation of neurotransmitter receptor activity", "Regulation of neurotransmitter transport", "Regulation of neurotransmitter uptake", "Regulation of neurotrophin trk receptor signaling pathway", "Regulation of neutrophil chemotaxis", "Regulation of neutrophil migration", "Regulation of nik nf kappab signaling", "Regulation of nitric oxide mediated signal transduction", "Regulation of nitric oxide metabolic process", "Regulation of nitric oxide synthase activity", "Regulation of nk t cell activation", "Regulation of nk t cell differentiation", "Regulation of nmda receptor activity", "Regulation of non motile cilium assembly", "Regulation of notch signaling pathway", "Regulation of nuclear cell cycle dna replication", "Regulation of nuclear division", "Regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Regulation of nuclear transcribed mrna poly a tail shortening", "Regulation of nuclease activity", "Regulation of nucleobase containing compound transport", "Regulation of nucleocytoplasmic transport", "Regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Regulation of nucleotide binding oligomerization domain containing signaling pathway", "Regulation of nucleotide biosynthetic process", "Regulation of nucleotide metabolic process", "Regulation of oligodendrocyte differentiation", "Regulation of opsonization", "Regulation of organ growth", "Regulation of organelle assembly", "Regulation of organelle organization", "Regulation of organelle transport along microtubule", "Regulation of organic acid transport", "Regulation of ossification", "Regulation of osteoblast differentiation", "Regulation of osteoblast proliferation", "Regulation of osteoclast differentiation", "Regulation of oxidative phosphorylation", "Regulation of oxidative stress induced cell death", "Regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Regulation of oxidoreductase activity", "Regulation of p38mapk cascade", "Regulation of pancreatic juice secretion", "Regulation of pattern recognition receptor signaling pathway", "Regulation of penile erection", "Regulation of peptidase activity", "Regulation of peptide transport", "Regulation of peptidyl lysine acetylation", "Regulation of peptidyl serine phosphorylation", "Regulation of peptidyl serine phosphorylation of stat protein", "Regulation of peptidyl threonine phosphorylation", "Regulation of peptidyl tyrosine phosphorylation", "Regulation of perk mediated unfolded protein response", "Regulation of peroxisome proliferator activated receptor signaling pathway", "Regulation of ph", "Regulation of phagocytosis", "Regulation of phenotypic switching", "Regulation of phosphatase activity", "Regulation of phosphatidylcholine biosynthetic process", "Regulation of phosphatidylcholine metabolic process", "Regulation of phosphatidylinositol 3 kinase activity", "Regulation of phosphatidylinositol 3 kinase signaling", "Regulation of phosphatidylinositol dephosphorylation", "Regulation of phospholipase a2 activity", "Regulation of phospholipase activity", "Regulation of phospholipase c activity", "Regulation of phospholipid biosynthetic process", "Regulation of phospholipid catabolic process", "Regulation of phospholipid metabolic process", "Regulation of phospholipid translocation", "Regulation of phospholipid transport", "Regulation of phosphoprotein phosphatase activity", "Regulation of phosphorus metabolic process", "Regulation of pigment cell differentiation", "Regulation of pigmentation", "Regulation of pinocytosis", "Regulation of plasma lipoprotein particle levels", "Regulation of plasma membrane organization", "Regulation of plasminogen activation", "Regulation of platelet activation", "Regulation of platelet aggregation", "Regulation of platelet derived growth factor receptor beta signaling pathway", "Regulation of platelet derived growth factor receptor signaling pathway", "Regulation of podosome assembly", "Regulation of polysaccharide metabolic process", "Regulation of post translational protein modification", "Regulation of postsynapse organization", "Regulation of postsynaptic density organization", "Regulation of postsynaptic membrane neurotransmitter receptor levels", "Regulation of postsynaptic membrane potential", "Regulation of postsynaptic neurotransmitter receptor activity", "Regulation of postsynaptic neurotransmitter receptor internalization", "Regulation of potassium ion import", "Regulation of potassium ion transmembrane transporter activity", "Regulation of potassium ion transport", "Regulation of presynapse organization", "Regulation of presynaptic cytosolic calcium ion concentration", "Regulation of pro b cell differentiation", "Regulation of production of molecular mediator of immune response", "Regulation of production of small rna involved in gene silencing by rna", "Regulation of programmed necrotic cell death", "Regulation of prostaglandin secretion", "Regulation of proteasomal protein catabolic process", "Regulation of proteasomal ubiquitin dependent protein catabolic process", "Regulation of protein acetylation", "Regulation of protein adp ribosylation", "Regulation of protein autophosphorylation", "Regulation of protein autoubiquitination", "Regulation of protein binding", "Regulation of protein catabolic process", "Regulation of protein catabolic process in the vacuole", "Regulation of protein complex stability", "Regulation of protein containing complex assembly", "Regulation of protein containing complex disassembly", "Regulation of protein deacetylation", "Regulation of protein dephosphorylation", "Regulation of protein depolymerization", "Regulation of protein deubiquitination", "Regulation of protein exit from endoplasmic reticulum", "Regulation of protein export from nucleus", "Regulation of protein folding", "Regulation of protein glycosylation", "Regulation of protein import", "Regulation of protein k63 linked ubiquitination", "Regulation of protein kinase a signaling", "Regulation of protein kinase activity", "Regulation of protein kinase c activity", "Regulation of protein kinase c signaling", "Regulation of protein lipidation", "Regulation of protein localization", "Regulation of protein localization to cell cortex", "Regulation of protein localization to cell periphery", "Regulation of protein localization to cell surface", "Regulation of protein localization to centrosome", "Regulation of protein localization to chromatin", "Regulation of protein localization to chromosome telomeric region", "Regulation of protein localization to cilium", "Regulation of protein localization to endosome", "Regulation of protein localization to membrane", "Regulation of protein localization to nucleolus", "Regulation of protein localization to nucleus", "Regulation of protein localization to plasma membrane", "Regulation of protein maturation", "Regulation of protein modification by small protein conjugation or removal", "Regulation of protein modification process", "Regulation of protein monoubiquitination", "Regulation of protein neddylation", "Regulation of protein phosphorylation", "Regulation of protein polymerization", "Regulation of protein polyubiquitination", "Regulation of protein secretion", "Regulation of protein serine threonine kinase activity", "Regulation of protein stability", "Regulation of protein sumoylation", "Regulation of protein targeting", "Regulation of protein targeting to membrane", "Regulation of protein tyrosine kinase activity", "Regulation of protein tyrosine phosphatase activity", "Regulation of proteolysis", "Regulation of proton transport", "Regulation of rab protein signal transduction", "Regulation of rac protein signal transduction", "Regulation of ras protein signal transduction", "Regulation of reactive oxygen species biosynthetic process", "Regulation of reactive oxygen species metabolic process", "Regulation of receptor binding", "Regulation of receptor catabolic process", "Regulation of receptor clustering", "Regulation of receptor internalization", "Regulation of receptor localization to synapse", "Regulation of receptor mediated endocytosis", "Regulation of receptor mediated endocytosis involved in cholesterol transport", "Regulation of receptor recycling", "Regulation of receptor signaling pathway via stat", "Regulation of regulated secretory pathway", "Regulation of relaxation of muscle", "Regulation of release of cytochrome c from mitochondria", "Regulation of release of sequestered calcium ion into cytosol", "Regulation of removal of superoxide radicals", "Regulation of renal system process", "Regulation of reproductive process", "Regulation of respiratory burst", "Regulation of respiratory gaseous exchange", "Regulation of respiratory gaseous exchange by nervous system process", "Regulation of respiratory system process", "Regulation of response to biotic stimulus", "Regulation of response to cytokine stimulus", "Regulation of response to dna damage stimulus", "Regulation of response to endoplasmic reticulum stress", "Regulation of response to external stimulus", "Regulation of response to extracellular stimulus", "Regulation of response to food", "Regulation of response to interferon gamma", "Regulation of response to osmotic stress", "Regulation of response to oxidative stress", "Regulation of response to reactive oxygen species", "Regulation of response to stress", "Regulation of response to tumor cell", "Regulation of response to wounding", "Regulation of retinal ganglion cell axon guidance", "Regulation of retinoic acid receptor signaling pathway", "Regulation of retrograde protein transport er to cytosol", "Regulation of retrograde transport endosome to golgi", "Regulation of rho dependent protein serine threonine kinase activity", "Regulation of rho protein signal transduction", "Regulation of rhodopsin mediated signaling pathway", "Regulation of ribonuclease activity", "Regulation of ribosome biogenesis", "Regulation of rig i signaling pathway", "Regulation of rna binding", "Regulation of rna export from nucleus", "Regulation of rna polymerase ii regulatory region sequence specific dna binding", "Regulation of rna polymerase ii transcription preinitiation complex assembly", "Regulation of rna splicing", "Regulation of rrna processing", "Regulation of ruffle assembly", "Regulation of ryanodine sensitive calcium release channel activity", "Regulation of sarcomere organization", "Regulation of secondary heart field cardioblast proliferation", "Regulation of secondary metabolic process", "Regulation of secretion", "Regulation of sensory perception", "Regulation of sequestering of triglyceride", "Regulation of sequestering of zinc ion", "Regulation of short term neuronal synaptic plasticity", "Regulation of signal transduction by p53 class mediator", "Regulation of signaling receptor activity", "Regulation of sister chromatid cohesion", "Regulation of skeletal muscle adaptation", "Regulation of skeletal muscle cell differentiation", "Regulation of skeletal muscle contraction", "Regulation of skeletal muscle contraction by calcium ion signaling", "Regulation of skeletal muscle fiber development", "Regulation of skeletal muscle tissue development", "Regulation of smad protein complex assembly", "Regulation of smad protein signal transduction", "Regulation of small gtpase mediated signal transduction", "Regulation of small molecule metabolic process", "Regulation of smooth muscle cell chemotaxis", "Regulation of smooth muscle cell differentiation", "Regulation of smooth muscle contraction", "Regulation of smoothened signaling pathway", "Regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Regulation of snrna transcription by rna polymerase ii", "Regulation of sodium ion transmembrane transport", "Regulation of sodium ion transport", "Regulation of sodium proton antiporter activity", "Regulation of somitogenesis", "Regulation of sphingolipid biosynthetic process", "Regulation of spindle assembly", "Regulation of spindle organization", "Regulation of spontaneous synaptic transmission", "Regulation of sprouting angiogenesis", "Regulation of srebp signaling pathway", "Regulation of stem cell differentiation", "Regulation of stem cell population maintenance", "Regulation of stem cell proliferation", "Regulation of steroid biosynthetic process", "Regulation of steroid hormone biosynthetic process", "Regulation of steroid hormone secretion", "Regulation of steroid metabolic process", "Regulation of sterol transport", "Regulation of store operated calcium channel activity", "Regulation of stress activated protein kinase signaling cascade", "Regulation of stress granule assembly", "Regulation of striated muscle cell differentiation", "Regulation of striated muscle contraction", "Regulation of substrate adhesion dependent cell spreading", "Regulation of sulfur metabolic process", "Regulation of superoxide anion generation", "Regulation of superoxide dismutase activity", "Regulation of superoxide metabolic process", "Regulation of supramolecular fiber organization", "Regulation of synapse assembly", "Regulation of synapse maturation", "Regulation of synapse structural plasticity", "Regulation of synapse structure or activity", "Regulation of synaptic plasticity", "Regulation of synaptic transmission dopaminergic", "Regulation of synaptic transmission gabaergic", "Regulation of synaptic transmission glutamatergic", "Regulation of synaptic vesicle clustering", "Regulation of synaptic vesicle endocytosis", "Regulation of synaptic vesicle exocytosis", "Regulation of synaptic vesicle priming", "Regulation of synaptic vesicle recycling", "Regulation of syncytium formation by plasma membrane fusion", "Regulation of system process", "Regulation of systemic arterial blood pressure", "Regulation of systemic arterial blood pressure by circulatory renin angiotensin", "Regulation of systemic arterial blood pressure by endothelin", "Regulation of systemic arterial blood pressure by hormone", "Regulation of systemic arterial blood pressure by norepinephrine epinephrine", "Regulation of systemic arterial blood pressure by renin angiotensin", "Regulation of systemic arterial blood pressure mediated by a chemical signal", "Regulation of t cell activation", "Regulation of t cell apoptotic process", "Regulation of t cell chemotaxis", "Regulation of t cell differentiation", "Regulation of t cell differentiation in thymus", "Regulation of t cell mediated cytotoxicity", "Regulation of t cell mediated immune response to tumor cell", "Regulation of t cell mediated immunity", "Regulation of t cell migration", "Regulation of t cell proliferation", "Regulation of t cell receptor signaling pathway", "Regulation of t circle formation", "Regulation of t helper 1 cell differentiation", "Regulation of t helper 1 type immune response", "Regulation of t helper 2 cell differentiation", "Regulation of t helper cell differentiation", "Regulation of tau protein kinase activity", "Regulation of telomerase activity", "Regulation of telomere capping", "Regulation of telomere maintenance", "Regulation of telomere maintenance via telomere lengthening", "Regulation of tetrapyrrole metabolic process", "Regulation of the force of heart contraction", "Regulation of thymocyte apoptotic process", "Regulation of tissue remodeling", "Regulation of tolerance induction", "Regulation of toll like receptor 3 signaling pathway", "Regulation of toll like receptor 4 signaling pathway", "Regulation of toll like receptor 7 signaling pathway", "Regulation of toll like receptor 9 signaling pathway", "Regulation of toll like receptor signaling pathway", "Regulation of tooth mineralization", "Regulation of tor signaling", "Regulation of torc2 signaling", "Regulation of trail activated apoptotic signaling pathway", "Regulation of trans synaptic signaling", "Regulation of transcription by glucose", "Regulation of transcription by rna polymerase i", "Regulation of transcription by rna polymerase iii", "Regulation of transcription elongation from rna polymerase ii promoter", "Regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Regulation of transcription from rna polymerase ii promoter in response to oxidative stress", "Regulation of transcription involved in g1 s transition of mitotic cell cycle", "Regulation of transcription of nucleolar large rrna by rna polymerase i", "Regulation of transcription regulatory region dna binding", "Regulation of transferase activity", "Regulation of transforming growth factor beta activation", "Regulation of transforming growth factor beta1 production", "Regulation of translation at synapse modulating synaptic transmission", "Regulation of translation in response to endoplasmic reticulum stress", "Regulation of translation in response to stress", "Regulation of translation initiation in response to endoplasmic reticulum stress", "Regulation of translational elongation", "Regulation of translational fidelity", "Regulation of translational initiation", "Regulation of translational initiation by eif2 alpha phosphorylation", "Regulation of translational initiation in response to stress", "Regulation of translational termination", "Regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Regulation of transmembrane transport", "Regulation of transmission of nerve impulse", "Regulation of transport", "Regulation of transporter activity", "Regulation of transposition", "Regulation of triglyceride biosynthetic process", "Regulation of triglyceride metabolic process", "Regulation of tube size", "Regulation of tumor necrosis factor mediated signaling pathway", "Regulation of type b pancreatic cell development", "Regulation of type i interferon mediated signaling pathway", "Regulation of ubiquitin dependent protein catabolic process", "Regulation of ubiquitin protein ligase activity", "Regulation of ubiquitin protein transferase activity", "Regulation of ubiquitin specific protease activity", "Regulation of unsaturated fatty acid biosynthetic process", "Regulation of urine volume", "Regulation of vacuole organization", "Regulation of vascular associated smooth muscle cell differentiation", "Regulation of vascular associated smooth muscle contraction", "Regulation of vascular endothelial growth factor receptor signaling pathway", "Regulation of vascular permeability", "Regulation of vascular wound healing", "Regulation of vasculature development", "Regulation of vasculogenesis", "Regulation of vasoconstriction", "Regulation of ventricular cardiac muscle cell action potential", "Regulation of very low density lipoprotein particle clearance", "Regulation of vesicle fusion", "Regulation of vesicle mediated transport", "Regulation of vesicle size", "Regulation of viral entry into host cell", "Regulation of viral genome replication", "Regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Regulation of viral process", "Regulation of viral transcription", "Regulation of vitamin d biosynthetic process", "Regulation of vitamin d receptor signaling pathway", "Regulation of vitamin metabolic process", "Regulation of voltage gated calcium channel activity", "Regulation of water loss via skin", "Regulation of wnt signaling pathway", "Regulation of wound healing", "Regulation of wound healing spreading of epidermal cells", "Regulation of xenophagy", "Regulatory t cell differentiation", "Relaxation of cardiac muscle", "Relaxation of muscle", "Release of cytochrome c from mitochondria", "Release of sequestered calcium ion into cytosol by endoplasmic reticulum", "Renal absorption", "Renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure", "Renal filtration", "Renal sodium excretion", "Renal sodium ion absorption", "Renal sodium ion transport", "Renal system process", "Renal system process involved in regulation of systemic arterial blood pressure", "Renal system vasculature development", "Renal tubular secretion", "Renal tubule development", "Renal vesicle development", "Renal vesicle formation", "Renal water homeostasis", "Replacement ossification", "Replication born double strand break repair via sister chromatid exchange", "Replication fork processing", "Replication fork protection", "Replicative senescence", "Reproduction", "Reproductive behavior", "Reproductive system development", "Rescue of stalled ribosome", "Resolution of meiotic recombination intermediates", "Resolution of recombination intermediates", "Respiratory burst", "Respiratory burst involved in defense response", "Respiratory burst involved in inflammatory response", "Respiratory chain complex iii assembly", "Respiratory chain complex iv assembly", "Respiratory electron transport chain", "Respiratory gaseous exchange by respiratory system", "Respiratory system development", "Respiratory system process", "Response to abiotic stimulus", "Response to acetylcholine", "Response to acid chemical", "Response to acidic ph", "Response to actinomycin d", "Response to activity", "Response to alcohol", "Response to aldosterone", "Response to alkaloid", "Response to amine", "Response to amino acid starvation", "Response to ammonium ion", "Response to amphetamine", "Response to amyloid beta", "Response to angiotensin", "Response to antibiotic", "Response to arsenic containing substance", "Response to arsenite ion", "Response to atp", "Response to auditory stimulus", "Response to axon injury", "Response to bacterium", "Response to bmp", "Response to cadmium ion", "Response to caffeine", "Response to calcium ion", "Response to camp", "Response to camptothecin", "Response to carbohydrate", "Response to catecholamine", "Response to cell cycle checkpoint signaling", "Response to cgmp", "Response to chemokine", "Response to cholesterol", "Response to cisplatin", "Response to cobalt ion", "Response to cocaine", "Response to cold", "Response to copper ion", "Response to corticosteroid", "Response to corticosterone", "Response to cortisol", "Response to cytokine", "Response to dexamethasone", "Response to dietary excess", "Response to dopamine", "Response to dsrna", "Response to electrical stimulus", "Response to endogenous stimulus", "Response to endoplasmic reticulum stress", "Response to epidermal growth factor", "Response to epinephrine", "Response to estradiol", "Response to estrogen", "Response to ethanol", "Response to ether", "Response to extracellular stimulus", "Response to fatty acid", "Response to fibroblast growth factor", "Response to fluid shear stress", "Response to folic acid", "Response to follicle stimulating hormone", "Response to food", "Response to forskolin", "Response to fungus", "Response to gamma radiation", "Response to glucagon", "Response to glycoside", "Response to gonadotropin", "Response to granulocyte macrophage colony stimulating factor", "Response to growth factor", "Response to growth hormone", "Response to heat", "Response to heparin", "Response to hepatocyte growth factor", "Response to histamine", "Response to hormone", "Response to human chorionic gonadotropin", "Response to hydrogen peroxide", "Response to hydroperoxide", "Response to hydrostatic pressure", "Response to hydroxyurea", "Response to hyperoxia", "Response to immobilization stress", "Response to increased oxygen levels", "Response to indole 3 methanol", "Response to inorganic substance", "Response to insecticide", "Response to insulin", "Response to interferon alpha", "Response to interferon beta", "Response to interferon gamma", "Response to interleukin 1", "Response to interleukin 12", "Response to interleukin 18", "Response to interleukin 3", "Response to interleukin 4", "Response to interleukin 6", "Response to interleukin 7", "Response to ionizing radiation", "Response to iron ii ion", "Response to iron ion", "Response to ischemia", "Response to isoquinoline alkaloid", "Response to ketone", "Response to l ascorbic acid", "Response to l glutamate", "Response to l phenylalanine derivative", "Response to lead ion", "Response to lectin", "Response to leptin", "Response to leucine", "Response to leukemia inhibitory factor", "Response to light intensity", "Response to light stimulus", "Response to lipid", "Response to lipoteichoic acid", "Response to lithium ion", "Response to luteinizing hormone", "Response to magnesium ion", "Response to manganese ion", "Response to mechanical stimulus", "Response to mercury ion", "Response to metal ion", "Response to methylmercury", "Response to mineralocorticoid", "Response to misfolded protein", "Response to mitochondrial depolarisation", "Response to molecule of bacterial origin", "Response to monosaccharide", "Response to muramyl dipeptide", "Response to muscle activity", "Response to muscle stretch", "Response to nerve growth factor", "Response to nicotine", "Response to nitric oxide", "Response to nitrogen compound", "Response to nitrosative stress", "Response to nutrient", "Response to oleic acid", "Response to organic cyclic compound", "Response to osmotic stress", "Response to oxidative stress", "Response to oxygen containing compound", "Response to oxygen glucose deprivation", "Response to oxygen levels", "Response to oxygen radical", "Response to pain", "Response to parathyroid hormone", "Response to peptide", "Response to peptide hormone", "Response to peptidoglycan", "Response to ph", "Response to phorbol 13 acetate 12 myristate", "Response to platelet derived growth factor", "Response to potassium ion", "Response to progesterone", "Response to prostaglandin", "Response to prostaglandin e", "Response to purine containing compound", "Response to radiation", "Response to reactive oxygen species", "Response to redox state", "Response to retinoic acid", "Response to salt", "Response to salt stress", "Response to selenium ion", "Response to sodium arsenite", "Response to sorbitol", "Response to starvation", "Response to staurosporine", "Response to steroid hormone", "Response to sterol", "Response to sterol depletion", "Response to temperature stimulus", "Response to testosterone", "Response to thyroglobulin triiodothyronine", "Response to thyroid hormone", "Response to thyroxine", "Response to topologically incorrect protein", "Response to toxic substance", "Response to transforming growth factor beta", "Response to tumor cell", "Response to tumor necrosis factor", "Response to type i interferon", "Response to uv", "Response to uv a", "Response to uv b", "Response to uv c", "Response to virus", "Response to vitamin", "Response to vitamin a", "Response to vitamin d", "Response to vitamin e", "Response to vitamin k", "Response to water", "Response to wounding", "Response to x ray", "Response to xenobiotic stimulus", "Response to yeast", "Response to zinc ion", "Reticulophagy", "Retina development in camera type eye", "Retina homeostasis", "Retina layer formation", "Retina morphogenesis in camera type eye", "Retina vasculature development in camera type eye", "Retina vasculature morphogenesis in camera type eye", "Retinal cell programmed cell death", "Retinal cone cell differentiation", "Retinal ganglion cell axon guidance", "Retinal metabolic process", "Retinal pigment epithelium development", "Retinal rod cell development", "Retinal rod cell differentiation", "Retinoic acid metabolic process", "Retinoic acid receptor signaling pathway", "Retinol metabolic process", "Retrograde axonal transport", "Retrograde trans synaptic signaling", "Retrograde trans synaptic signaling by lipid", "Retrograde transport endosome to golgi", "Retrograde transport vesicle recycling within golgi", "Retrograde vesicle mediated transport golgi to endoplasmic reticulum", "Reverse cholesterol transport", "Reversible differentiation", "Rho protein signal transduction", "Rhodopsin mediated signaling pathway", "Rhythmic behavior", "Rhythmic process", "Riboflavin metabolic process", "Ribonucleoprotein complex biogenesis", "Ribonucleoprotein complex disassembly", "Ribonucleoprotein complex localization", "Ribonucleoprotein complex subunit organization", "Ribonucleoside catabolic process", "Ribonucleoside diphosphate biosynthetic process", "Ribonucleoside diphosphate catabolic process", "Ribonucleoside diphosphate metabolic process", "Ribonucleoside metabolic process", "Ribonucleoside monophosphate biosynthetic process", "Ribonucleoside monophosphate catabolic process", "Ribonucleoside monophosphate metabolic process", "Ribonucleoside triphosphate biosynthetic process", "Ribonucleoside triphosphate metabolic process", "Ribonucleotide catabolic process", "Ribose phosphate biosynthetic process", "Ribose phosphate metabolic process", "Ribosomal large subunit assembly", "Ribosomal large subunit biogenesis", "Ribosomal large subunit export from nucleus", "Ribosomal small subunit assembly", "Ribosomal small subunit biogenesis", "Ribosomal small subunit export from nucleus", "Ribosomal subunit export from nucleus", "Ribosome assembly", "Ribosome associated ubiquitin dependent protein catabolic process", "Ribosome biogenesis", "Ribosome disassembly", "Rig i signaling pathway", "Righting reflex", "Rna 3 end processing", "Rna 3 uridylation", "Rna 5 end processing", "Rna capping", "Rna catabolic process", "Rna decapping", "Rna dependent dna biosynthetic process", "Rna destabilization", "Rna export from nucleus", "Rna guanine n7 methylation", "Rna import into mitochondrion", "Rna interference", "Rna localization", "Rna mediated gene silencing by inhibition of translation", "Rna methylation", "Rna modification", "Rna phosphodiester bond hydrolysis", "Rna phosphodiester bond hydrolysis endonucleolytic", "Rna phosphodiester bond hydrolysis exonucleolytic", "Rna polyadenylation", "Rna polymerase i preinitiation complex assembly", "Rna polymerase ii preinitiation complex assembly", "Rna processing", "Rna secondary structure unwinding", "Rna splicing", "Rna splicing via endonucleolytic cleavage and ligation", "Rna splicing via transesterification reactions", "Rna stabilization", "Rna surveillance", "Roof of mouth development", "Rostrocaudal neural tube patterning", "Roundabout signaling pathway", "Rrna 3 end processing", "Rrna 5 end processing", "Rrna base methylation", "Rrna catabolic process", "Rrna metabolic process", "Rrna methylation", "Rrna modification", "Rrna pseudouridine synthesis", "Rrna transcription", "Rrna transport", "Ruffle assembly", "Ruffle organization", "S adenosylmethionine cycle", "S adenosylmethionine metabolic process", "Salivary gland development", "Sarcomere organization", "Sarcoplasmic reticulum calcium ion transport", "Satellite cell activation involved in skeletal muscle regeneration", "Scarna localization to cajal body", "Scf dependent proteasomal ubiquitin dependent protein catabolic process", "Schwann cell development", "Schwann cell differentiation", "Schwann cell proliferation", "Second messenger mediated signaling", "Secondary alcohol metabolic process", "Secondary metabolic process", "Secondary metabolite biosynthetic process", "Secretion", "Secretion by tissue", "Secretion of lysosomal enzymes", "Secretory granule localization", "Secretory granule organization", "Segment specification", "Segmentation", "Selective autophagy", "Self proteolysis", "Semaphorin plexin signaling pathway", "Semaphorin plexin signaling pathway involved in neuron projection guidance", "Semi lunar valve development", "Seminiferous tubule development", "Sensory organ development", "Sensory organ morphogenesis", "Sensory perception", "Sensory perception of light stimulus", "Sensory perception of mechanical stimulus", "Sensory perception of pain", "Sensory system development", "Septum primum development", "Sequestering of actin monomers", "Sequestering of calcium ion", "Sequestering of iron ion", "Sequestering of metal ion", "Sequestering of triglyceride", "Sequestering of zinc ion", "Serine family amino acid biosynthetic process", "Serine family amino acid catabolic process", "Serine family amino acid metabolic process", "Serine phosphorylation of stat protein", "Serine transport", "Serotonin metabolic process", "Sertoli cell development", "Sertoli cell differentiation", "Sex determination", "Sex differentiation", "Short chain fatty acid catabolic process", "Short chain fatty acid metabolic process", "Short term memory", "Signal peptide processing", "Signal release", "Signal transduction by p53 class mediator", "Signal transduction in absence of ligand", "Signal transduction in response to dna damage", "Signal transduction involved in regulation of gene expression", "Signaling receptor ligand precursor processing", "Single fertilization", "Single strand break repair", "Single stranded viral rna replication via double stranded dna intermediate", "Sister chromatid cohesion", "Sister chromatid segregation", "Skeletal muscle acetylcholine gated channel clustering", "Skeletal muscle adaptation", "Skeletal muscle cell differentiation", "Skeletal muscle cell proliferation", "Skeletal muscle contraction", "Skeletal muscle fiber differentiation", "Skeletal muscle organ development", "Skeletal muscle satellite cell activation", "Skeletal muscle tissue regeneration", "Skeletal myofibril assembly", "Skeletal system development", "Skeletal system morphogenesis", "Skin development", "Skin epidermis development", "Skin morphogenesis", "Smad protein complex assembly", "Smad protein signal transduction", "Small gtpase mediated signal transduction", "Small molecule biosynthetic process", "Small molecule catabolic process", "Small molecule metabolic process", "Small nucleolar ribonucleoprotein complex assembly", "Small rna loading onto risc", "Smooth muscle adaptation", "Smooth muscle cell apoptotic process", "Smooth muscle cell chemotaxis", "Smooth muscle cell differentiation", "Smooth muscle cell migration", "Smooth muscle cell proliferation", "Smooth muscle contraction", "Smooth muscle tissue development", "Smoothened signaling pathway", "Smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Snare complex assembly", "Sno s rna metabolic process", "Sno s rna processing", "Snorna localization", "Snrna metabolic process", "Snrna modification", "Snrna processing", "Snrna transcription", "Snrna transcription by rna polymerase ii", "Snrna transcription by rna polymerase iii", "Snrna transport", "Sodium independent organic anion transport", "Sodium ion export across plasma membrane", "Sodium ion homeostasis", "Sodium ion import across plasma membrane", "Sodium ion transmembrane transport", "Sodium ion transport", "Somatic diversification of immune receptors", "Somatic diversification of immune receptors via somatic mutation", "Somatic diversification of immunoglobulins", "Somatic diversification of immunoglobulins involved in immune response", "Somatic diversification of t cell receptor genes", "Somatic stem cell population maintenance", "Somite development", "Somite rostral caudal axis specification", "Somitogenesis", "Specification of animal organ identity", "Specification of symmetry", "Sperm capacitation", "Sperm dna condensation", "Sperm egg recognition", "Sperm motility", "Spermatid differentiation", "Spermatid nucleus differentiation", "Spermatogenesis exchange of chromosomal proteins", "Spermidine metabolic process", "Spermine metabolic process", "Sphingoid metabolic process", "Sphingolipid biosynthetic process", "Sphingolipid mediated signaling pathway", "Sphingolipid metabolic process", "Sphingolipid translocation", "Sphingomyelin biosynthetic process", "Sphingomyelin catabolic process", "Sphingomyelin metabolic process", "Sphingosine biosynthetic process", "Spinal cord development", "Spinal cord motor neuron differentiation", "Spindle assembly", "Spindle assembly involved in female meiosis", "Spindle elongation", "Spindle localization", "Spindle midzone assembly", "Spindle organization", "Spleen development", "Spliceosomal complex assembly", "Spliceosomal conformational changes to generate catalytic conformation", "Spliceosomal snrnp assembly", "Spliceosomal tri snrnp complex assembly", "Spontaneous synaptic transmission", "Sprouting angiogenesis", "Srp dependent cotranslational protein targeting to membrane", "Srp dependent cotranslational protein targeting to membrane signal sequence recognition", "Srp dependent cotranslational protein targeting to membrane translocation", "Startle response", "Stem cell differentiation", "Stem cell division", "Stem cell proliferation", "Steroid biosynthetic process", "Steroid catabolic process", "Steroid esterification", "Steroid hormone biosynthetic process", "Steroid hormone mediated signaling pathway", "Steroid hormone secretion", "Steroid metabolic process", "Sterol biosynthetic process", "Sterol homeostasis", "Sterol import", "Sterol metabolic process", "Sterol transport", "Stress activated protein kinase signaling cascade", "Stress fiber assembly", "Stress granule assembly", "Stress granule disassembly", "Stress induced premature senescence", "Stress response to metal ion", "Striated muscle adaptation", "Striated muscle cell apoptotic process", "Striated muscle cell development", "Striated muscle cell differentiation", "Striated muscle cell proliferation", "Striated muscle contraction", "Striatum development", "Subpallium development", "Substantia nigra development", "Substrate adhesion dependent cell spreading", "Substrate dependent cell migration", "Substrate dependent cell migration cell extension", "Substrate independent telencephalic tangential migration", "Subtelomeric heterochromatin assembly", "Succinate metabolic process", "Succinate transmembrane transport", "Succinyl coa metabolic process", "Suckling behavior", "Sugar mediated signaling pathway", "Sulfate transport", "Sulfur amino acid biosynthetic process", "Sulfur amino acid catabolic process", "Sulfur amino acid metabolic process", "Sulfur compound biosynthetic process", "Sulfur compound catabolic process", "Sulfur compound metabolic process", "Sulfur compound transport", "Superoxide anion generation", "Superoxide metabolic process", "Suppression of viral release by host", "Supramolecular fiber organization", "Sympathetic ganglion development", "Sympathetic nervous system development", "Synapse assembly", "Synapse maturation", "Synapse organization", "Synapse pruning", "Synaptic membrane adhesion", "Synaptic signaling", "Synaptic transmission dopaminergic", "Synaptic transmission gabaergic", "Synaptic transmission glutamatergic", "Synaptic vesicle budding", "Synaptic vesicle clustering", "Synaptic vesicle cytoskeletal transport", "Synaptic vesicle docking", "Synaptic vesicle endosomal processing", "Synaptic vesicle exocytosis", "Synaptic vesicle localization", "Synaptic vesicle maturation", "Synaptic vesicle membrane organization", "Synaptic vesicle priming", "Synaptic vesicle recycling", "Synaptic vesicle recycling via endosome", "Synaptic vesicle transport", "Synaptic vesicle uncoating", "Synaptonemal complex organization", "Syncytium formation", "T cell activation", "T cell activation involved in immune response", "T cell apoptotic process", "T cell chemotaxis", "T cell cytokine production", "T cell differentiation", "T cell differentiation in thymus", "T cell differentiation involved in immune response", "T cell extravasation", "T cell homeostasis", "T cell lineage commitment", "T cell mediated cytotoxicity", "T cell mediated immune response to tumor cell", "T cell mediated immunity", "T cell migration", "T cell proliferation", "T cell proliferation involved in immune response", "T cell receptor signaling pathway", "T cell selection", "T cell tolerance induction", "T helper 1 cell differentiation", "T helper 1 type immune response", "T helper 17 cell differentiation", "T helper 17 cell lineage commitment", "T helper 17 type immune response", "T helper 2 cell differentiation", "T helper cell lineage commitment", "T tubule organization", "Tail anchored membrane protein insertion into er membrane", "Tangential migration from the subventricular zone to the olfactory bulb", "Taxis", "Telencephalon development", "Telencephalon glial cell migration", "Telencephalon regionalization", "Telomerase holoenzyme complex assembly", "Telomerase rna localization", "Telomere capping", "Telomere maintenance", "Telomere maintenance in response to dna damage", "Telomere maintenance via recombination", "Telomere maintenance via semi conservative replication", "Telomere maintenance via telomere lengthening", "Telomere organization", "Telomeric d loop disassembly", "Telomeric loop disassembly", "Temperature homeostasis", "Terminal button organization", "Termination of rna polymerase ii transcription", "Terpenoid biosynthetic process", "Terpenoid metabolic process", "Tertiary alcohol metabolic process", "Tetrahydrobiopterin metabolic process", "Tetrahydrofolate biosynthetic process", "Tetrahydrofolate interconversion", "Tetrahydrofolate metabolic process", "Tetrapyrrole biosynthetic process", "Tetrapyrrole catabolic process", "Tetrapyrrole metabolic process", "Thalamus development", "Thioester biosynthetic process", "Thioester metabolic process", "Thorax and anterior abdomen determination", "Threonine catabolic process", "Threonine metabolic process", "Thrombin activated receptor signaling pathway", "Thrombopoietin mediated signaling pathway", "Thymocyte apoptotic process", "Thymus development", "Thyroid gland development", "Thyroid hormone generation", "Thyroid hormone mediated signaling pathway", "Thyroid hormone metabolic process", "Tight junction organization", "Tissue development", "Tissue migration", "Tissue morphogenesis", "Tissue regeneration", "Tissue remodeling", "Tolerance induction", "Toll like receptor 3 signaling pathway", "Toll like receptor 4 signaling pathway", "Toll like receptor 7 signaling pathway", "Toll like receptor 8 signaling pathway", "Toll like receptor 9 signaling pathway", "Toll like receptor signaling pathway", "Tongue development", "Tongue morphogenesis", "Tooth mineralization", "Tor signaling", "Torc1 signaling", "Torc2 signaling", "Toxin metabolic process", "Toxin transport", "Trabecula formation", "Trabecula morphogenesis", "Trachea development", "Trachea formation", "Trachea morphogenesis", "Trail activated apoptotic signaling pathway", "Trans synaptic signaling by lipid", "Trans synaptic signaling by trans synaptic complex", "Trans synaptic signaling modulating synaptic transmission", "Transcription by rna polymerase i", "Transcription by rna polymerase iii", "Transcription coupled nucleotide excision repair", "Transcription dependent tethering of rna polymerase ii gene dna at nuclear periphery", "Transcription elongation from rna polymerase i promoter", "Transcription elongation from rna polymerase ii promoter", "Transcription factor catabolic process", "Transcription initiation from rna polymerase i promoter", "Transcription initiation from rna polymerase ii promoter", "Transcription initiation from rna polymerase iii promoter", "Transcription preinitiation complex assembly", "Transcytosis", "Transepithelial chloride transport", "Transepithelial transport", "Transferrin transport", "Transforming growth factor beta activation", "Transforming growth factor beta production", "Transforming growth factor beta receptor signaling pathway", "Transforming growth factor beta1 production", "Transition between fast and slow fiber", "Transition metal ion homeostasis", "Transition metal ion transport", "Translational elongation", "Translational initiation", "Translational readthrough", "Translational termination", "Translesion synthesis", "Translocation of molecules into host", "Transmembrane receptor protein serine threonine kinase signaling pathway", "Transmembrane receptor protein tyrosine kinase signaling pathway", "Transmembrane receptor protein tyrosine phosphatase signaling pathway", "Transmembrane transport", "Transmission of nerve impulse", "Transport along microtubule", "Transport of virus", "Transposition", "Transposition rna mediated", "Tricarboxylic acid cycle", "Tricarboxylic acid metabolic process", "Triglyceride biosynthetic process", "Triglyceride metabolic process", "Tripartite regional subdivision", "Tripeptide transmembrane transport", "Tripeptide transport", "Trivalent inorganic anion homeostasis", "Trna 3 end processing", "Trna 5 end processing", "Trna 5 leader removal", "Trna aminoacylation for mitochondrial protein translation", "Trna catabolic process", "Trna metabolic process", "Trna methylation", "Trna modification", "Trna processing", "Trna pseudouridine synthesis", "Trna thio modification", "Trna threonylcarbamoyladenosine metabolic process", "Trna transcription", "Trna transport", "Trna wobble base modification", "Trna wobble uridine modification", "Trophectodermal cell differentiation", "Trophoblast cell migration", "Trophoblast giant cell differentiation", "Tryptophan transport", "Tube development", "Tube formation", "Tube morphogenesis", "Tubulin complex assembly", "Tubulin deacetylation", "Tumor necrosis factor mediated signaling pathway", "Tumor necrosis factor superfamily cytokine production", "Type 2 immune response", "Type b pancreatic cell apoptotic process", "Type b pancreatic cell development", "Type b pancreatic cell proliferation", "Type i interferon production", "Type i pneumocyte differentiation", "Tyrosine catabolic process", "Tyrosine metabolic process", "Tyrosine phosphorylation of stat protein", "U4 snrna 3 end processing", "Ubiquinone metabolic process", "Ubiquitin dependent endocytosis", "Ubiquitin dependent erad pathway", "Ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin dependent smad protein catabolic process", "Ubiquitin independent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin recycling", "Udp glucose metabolic process", "Udp n acetylglucosamine biosynthetic process", "Udp n acetylglucosamine metabolic process", "Ump biosynthetic process", "Unsaturated fatty acid biosynthetic process", "Unsaturated fatty acid metabolic process", "Urate metabolic process", "Urate transport", "Urea cycle", "Urea metabolic process", "Ureter development", "Ureter morphogenesis", "Ureteric bud elongation", "Urogenital system development", "Uronic acid metabolic process", "Uterus development", "Uterus morphogenesis", "Utp biosynthetic process", "Utp metabolic process", "Uv damage excision repair", "Uv protection", "V d j recombination", "Vacuolar acidification", "Vacuolar localization", "Vacuolar proton transporting v type atpase complex assembly", "Vacuolar transport", "Vacuole organization", "Vagina development", "Valine metabolic process", "Vascular associated smooth muscle cell apoptotic process", "Vascular associated smooth muscle cell differentiation", "Vascular associated smooth muscle cell migration", "Vascular associated smooth muscle cell proliferation", "Vascular associated smooth muscle contraction", "Vascular endothelial cell proliferation", "Vascular endothelial growth factor production", "Vascular endothelial growth factor receptor 2 signaling pathway", "Vascular endothelial growth factor receptor signaling pathway", "Vascular endothelial growth factor signaling pathway", "Vascular process in circulatory system", "Vascular transport", "Vascular wound healing", "Vasculature development", "Vasculogenesis", "Vasoconstriction", "Vasodilation", "Ventral spinal cord development", "Ventricular cardiac muscle cell action potential", "Ventricular cardiac muscle cell development", "Ventricular cardiac muscle cell differentiation", "Ventricular cardiac muscle cell membrane repolarization", "Ventricular cardiac muscle tissue development", "Ventricular cardiac muscle tissue morphogenesis", "Ventricular compact myocardium morphogenesis", "Ventricular septum development", "Ventricular septum morphogenesis", "Ventricular system development", "Ventricular trabecula myocardium morphogenesis", "Very long chain fatty acid catabolic process", "Very long chain fatty acid metabolic process", "Very low density lipoprotein particle assembly", "Very low density lipoprotein particle clearance", "Vesicle budding from membrane", "Vesicle cargo loading", "Vesicle cytoskeletal trafficking", "Vesicle docking", "Vesicle docking involved in exocytosis", "Vesicle fusion to plasma membrane", "Vesicle fusion with golgi apparatus", "Vesicle localization", "Vesicle mediated cholesterol transport", "Vesicle mediated transport", "Vesicle mediated transport between endosomal compartments", "Vesicle mediated transport in synapse", "Vesicle mediated transport to the plasma membrane", "Vesicle organization", "Vesicle targeting", "Vesicle targeting rough er to cis golgi", "Vesicle targeting to from or within golgi", "Vesicle tethering", "Vesicle tethering to golgi", "Vesicle transport along microtubule", "Vesicle uncoating", "Viral budding", "Viral gene expression", "Viral genome replication", "Viral life cycle", "Viral process", "Viral protein processing", "Viral release from host cell", "Viral rna genome replication", "Viral transcription", "Viral translation", "Viral translational termination reinitiation", "Virion assembly", "Virion attachment to host cell", "Visual behavior", "Vitamin a metabolic process", "Vitamin b6 metabolic process", "Vitamin biosynthetic process", "Vitamin catabolic process", "Vitamin d biosynthetic process", "Vitamin d metabolic process", "Vitamin d receptor signaling pathway", "Vitamin k metabolic process", "Vitamin metabolic process", "Vitamin transmembrane transport", "Vitamin transport", "Vocalization behavior", "Voluntary musculoskeletal movement", "Walking behavior", "Water homeostasis", "Water soluble vitamin biosynthetic process", "Water soluble vitamin metabolic process", "Water transport", "White fat cell differentiation", "Wnt protein secretion", "Wnt signaling pathway involved in heart development", "Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation", "Wound healing", "Wound healing involved in inflammatory response", "Wound healing spreading of epidermal cells", "Xenobiotic catabolic process", "Xenobiotic export", "Xenobiotic metabolic process", "Xenobiotic transmembrane transport", "Xenobiotic transport", "Xenobiotic transport across blood brain barrier", "Xenophagy", "Xmp metabolic process", "Zinc ion homeostasis", "Zinc ion transport", "Zygotic determination of anterior posterior axis embryo", "Zymogen activation", "Zymogen inhibition"], "available_proteins": ["AAAS", "AACS", "AAGAB", "AAK1", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ADA", "ADAM17", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKT1", "AKT1S1", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG13", "ALG5", "ALKBH1", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APC", "APEH", "APEX1", "API5", "APOBEC3C", "APOO", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP3", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGAP35", "ARHGAP5", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL6IP5", "ARL8B", "ARMC1", "ARMC10", "ARMC6", "ARMC9", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARVCF", "ASAH1", "ASB6", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATE1", "ATF7IP", "ATG3", "ATG4B", "ATG9A", "ATIC", "ATL2", "ATL3", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATRX", "ATXN10", "ATXN2", "ATXN2L", "AUP1", "B3GALT6", "B4GALT1", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BCAP31", "BCAS2", "BCAT2", "BCCIP", "BCL2L12", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BDH2", "BICD2", "BIRC6", "BLM", "BLMH", "BLOC1S1", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOD1L1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAP", "BRAT1", "BRCA1", "BRD2", "BRD4", "BRIX1", "BSG", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C12orf73", "C19orf70", "C1QBP", "C20orf27", "C21orf59", "C2CD5", "C2orf49", "C5orf51", "CAB39", "CACTIN", "CACUL1", "CACYBP", "CAD", "CADM1", "CALD1", "CALM3", "CALR", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAP2", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CASK", "CASP2", "CASP3", "CAST", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC124", "CCDC22", "CCDC47", "CCDC51", "CCDC6", "CCDC88A", "CCDC93", "CCDC94", "CCNA2", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC23", "CDC25C", "CDC27", "CDC37", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP3", "CDK6", "CDKAL1", "CDKN2A", "CDKN2AIP", "CDS2", "CDX2", "CEBPZ", "CECR2", "CELF1", "CENPE", "CENPI", "CENPU", "CENPV", "CEP250", "CEP44", "CEP55", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHCHD4", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP4A", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHP1", "CHRAC1", "CHST14", "CHTF18", "CHTF8", "CHTOP", "CHUK", "CIAPIN1", "CIRBP", "CISD2", "CIZ1", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLN6", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTA", "CLTC", "CLU", "CLUH", "CMAS", "CMBL", "CMPK1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNOT1", "CNOT11", "CNOT3", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COASY", "COG2", "COG3", "COG4", "COG7", "COIL", "COLEC12", "COLGALT1", "COMMD1", "COMMD7", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "CORO1B", "CORO1C", "COTL1", "COX11", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTDSPL2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CTTNBP2NL", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC22", "CWF19L1", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF7", "DCAF8", "DCAKD", "DCD", "DCP1A", "DCP1B", "DCP2", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTPP1", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEK", "DENND4C", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHODH", "DHPS", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DIS3L2", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTL", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EGFR", "EGLN1", "EHBP1", "EHD1", "EHD4", "EHMT2", "EIF2A", "EIF2AK2", "EIF2AK4", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP4", "EMC1", "EMC2", "EMC3", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENSA", "EPB41", "EPB41L2", "EPB41L5", "EPDR1", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6B", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXTL3", "EZR", "F11R", "FABP5", "FAF1", "FAF2", "FAH", "FAM118B", "FAM160A2", "FAM162A", "FAM208A", "FAM213A", "FAM49B", "FAM50A", "FAM83D", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FBL", "FBXO22", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNDC3A", "FNTA", "FNTB", "FOXRED1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLM", "GCN1", "GDAP1", "GDAP2", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GEMIN8", "GET4", "GFM1", "GFPT1", "GGA1", "GGCT", "GGCX", "GGH", "GGT7", "GHITM", "GID4", "GID8", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNE", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLM1", "GOLPH3", "GOLPH3L", "GOLT1B", "GOPC", "GORASP2", "GOT1", "GOT2", "GPAM", "GPATCH4", "GPD2", "GPHN", "GPI", "GPKOW", "GPR107", "GPR108", "GPR89B", "GPS1", "GPSM1", "GPT2", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSDME", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTSE1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAGH", "HARS2", "HAT1", "HAUS1", "HAUS2", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEBP1", "HECTD1", "HELLS", "HERC4", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMGXB4", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOXD13", "HP1BP3", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA6", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HUS1", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IER3IP1", "IFIT5", "IFNGR1", "IFT27", "IFT88", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "IKBKB", "IKBKG", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPA1", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS11", "INTS12", "INTS13", "INTS14", "INTS3", "INTS7", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRS4", "ISCU", "ISG20L2", "ISOC2", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITSN2", "IVD", "IWS1", "JAGN1", "JMJD6", "JUP", "KARS", "KAT7", "KCTD12", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0368", "KIAA0391", "KIAA1211", "KIAA1468", "KIF11", "KIF14", "KIF15", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "L2HGDH", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCMT1", "LDHA", "LDHB", "LDLR", "LDLRAP1", "LEMD2", "LEMD3", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LNPEP", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRP1", "LRPAP1", "LRPPRC", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRWD1", "LSM14A", "LSM14B", "LSM2", "LSM6", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYPLAL1", "LZTFL1", "LZTS2", "M6PR", "MACF1", "MAD1L1", "MAGED1", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K3", "MAP4", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARK1", "MARK2", "MARS", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MEAF6", "MECP2", "MED1", "MED14", "MED16", "MED21", "MED23", "MED24", "MED4", "MEPCE", "METAP1", "METAP2", "METTL1", "METTL13", "METTL16", "METTL3", "MFAP1", "MFF", "MFN1", "MFN2", "MFSD10", "MFSD5", "MGAT1", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MICALL1", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MKLN1", "MKRN2", "MLEC", "MMAB", "MMGT1", "MMS19", "MOGS", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRC2", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL16", "MRPL19", "MRPL2", "MRPL22", "MRPL23", "MRPL28", "MRPL3", "MRPL37", "MRPL43", "MRPL44", "MRPL47", "MRPL55", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS27", "MRPS28", "MRPS30", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTERF3", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR2", "MTOR", "MTPAP", "MTR", "MTSS1L", "MTX1", "MTX2", "MTX3", "MUT", "MVK", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA16", "NAA35", "NAA40", "NAA50", "NACC1", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCDN", "NCKAP1", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "ND5", "NDC1", "NDC80", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEFL", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NFATC2IP", "NFKB1", "NFS1", "NFU1", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NMD3", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NRDE2", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSUN2", "NSUN5", "NSUN6", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NUB1", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PATL1", "PAXIP1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNP", "PCNT", "PCYOX1", "PDCD11", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDS5A", "PDS5B", "PDXDC1", "PDXK", "PDZD8", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN1", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGGT1B", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PI4KB", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIH1D1", "PIK3C2A", "PIK3C3", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2B", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCB3", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNN", "PNP", "PNPLA6", "PNPLA8", "PNPO", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2D", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "PON2", "POP1", "POR", "PPA2", "PPAN", "PPAT", "PPFIA1", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKAR2B", "PRKCD", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF39", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN23", "PTPN9", "PTPRF", "PTRH2", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "PYM1", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABEP1", "RABEPK", "RABGAP1", "RABGGTA", "RABGGTB", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RANGRF", "RAP1GDS1", "RAPGEF2", "RAPGEF6", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM39", "RBM4", "RBM42", "RBM47", "RBM5", "RBM8A", "RBMX", "RBPMS", "RCC1", "RCC2", "RCL1", "RCN1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "RECQL5", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "RETREG3", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOX1", "RIOX2", "RIPK1", "RMDN1", "RMND5A", "RNASEH2A", "RNASEH2B", "RNASET2", "RNF14", "RNF20", "RNF219", "RNF220", "RNF40", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RPUSD2", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCA", "RTCB", "RTF1", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SAAL1", "SACM1L", "SACS", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SASS6", "SBDS", "SCAF1", "SCAF11", "SCAF4", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCYL2", "SDAD1", "SDCBP", "SDF2L1", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD7", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIN3A", "SIRT1", "SKA1", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A5", "SLC25A6", "SLC27A4", "SLC30A7", "SLC35A4", "SLC35B2", "SLC35F2", "SLC38A2", "SLC3A2", "SLC6A15", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SLU7", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC6", "SMCHD1", "SMG8", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SNAP23", "SNAP29", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPC24", "SPC25", "SPCS2", "SPDL1", "SPECC1", "SPECC1L", "SPEN", "SPHK2", "SPNS1", "SPOUT1", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRBD1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3NL", "STAT1", "STAT3", "STAU1", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX4", "STX6", "STX7", "STX8", "STXBP2", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE1", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACC3", "TACO1", "TADA3", "TAF15", "TAGLN2", "TALDO1", "TAMM41", "TANGO6", "TAP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D17", "TBC1D2B", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCA", "TBCC", "TBCD", "TBCE", "TBK1", "TBL1XR1", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TDRD7", "TDRKH", "TECR", "TELO2", "TERF2", "TERF2IP", "TES", "TEX264", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGS1", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM17A", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TIMM9", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLN1", "TM9SF2", "TM9SF3", "TM9SF4", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM11", "TMEM126A", "TMEM126B", "TMEM165", "TMEM199", "TMEM201", "TMEM206", "TMEM214", "TMEM230", "TMEM30A", "TMEM33", "TMEM43", "TMEM59", "TMEM63A", "TMEM87A", "TMEM97", "TMF1", "TMLHE", "TMOD1", "TMOD3", "TMTC3", "TMX1", "TMX2", "TMX3", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOM1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPMT", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIO", "TRIP12", "TRIP13", "TRIR", "TRMT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMU", "TROVE2", "TRUB1", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN10", "TSPAN6", "TSPO", "TSPYL1", "TSR1", "TSR2", "TTC1", "TTC19", "TTC26", "TTC28", "TTC37", "TTC4", "TTF2", "TTI1", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXN2", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAP2L", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE2T", "UBE3A", "UBE3C", "UBE4A", "UBL5", "UBLCP1", "UBP1", "UBQLN1", "UBQLN2", "UBQLN4", "UBR1", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119B", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "UROD", "USO1", "USP10", "USP11", "USP14", "USP15", "USP24", "USP28", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "UXT", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VPS13A", "VPS18", "VPS25", "VPS26A", "VPS26B", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37C", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK2", "VTA1", "VTI1B", "WAPL", "WARS", "WARS2", "WASHC3", "WASHC5", "WASL", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR36", "WDR4", "WDR41", "WDR43", "WDR45B", "WDR46", "WDR48", "WDR5", "WDR6", "WDR61", "WDR70", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WNK1", "WNK2", "WRAP53", "WRAP73", "WTAP", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YAP1", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YEATS4", "YIF1A", "YIPF4", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF1", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZFYVE16", "ZMPSTE24", "ZMYM4", "ZMYND8", "ZNF24", "ZNF281", "ZNF318", "ZNF326", "ZNF512B", "ZNF598", "ZNF622", "ZNF638", "ZPR1", "ZRANB2", "ZSWIM8", "ZW10", "ZWILCH", "ZYX"], "leading_proteins": ["ABCB1", "ABHD10", "ABHD12", "ACAT2", "ACBD5", "ACOT7", "ACOX1", "ACP6", "ACSL3", "ACTN2", "ACTN4", "ADAM17", "ADNP", "ADPGK", "AGK", "AIFM1", "AKAP1", "AKAP8", "AKAP8L", "AKAP9", "AKT1", "AKT1S1", "ALDH1A2", "ALDH1B1", "ALDH3A2", "ALG1", "ALKBH1", "ANAPC2", "ANAPC5", "ANAPC7", "ANK3", "ANKLE2", "ANLN", "ANXA1", "AP3M1", "APC", "APOBEC3C", "APOO", "APPL1", "ARF4", "ARF5", "ARF6", "ARFIP2", "ARHGAP1", "ARL1", "ARL2", "ARL6IP1", "ARL8B", "ARMC10", "ARMCX3", "ASAH1", "ASCC3", "ATAD3A", "ATG3", "ATG9A", "ATL2", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP2A2", "ATP2B1", "ATP5F1", "ATP5J2", "ATP5L", "ATP6", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V1B2", "ATPIF1", "ATRX", "B4GALT1", "B4GAT1", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAX", "BCL2L13", "BICD2", "BLOC1S1", "BRAT1", "BSG", "BUB1", "BUB1B", "C12orf43", "C12orf73", "C19orf70", "C1QBP", "C5orf51", "CALM3", "CAMK1", "CAP2", "CAPN2", "CAPZB", "CARM1", "CASK", "CASP3", "CCAR2", "CCDC22", "CCDC47", "CCDC51", "CCNA2", "CCT2", "CCT5", "CD2AP", "CDC42", "CDC42BPB", "CDK4", "CDK5", "CDK5RAP1", "CDKAL1", "CDKN2A", "CDS2", "CDX2", "CENPE", "CENPI", "CENPV", "CEP44", "CERS2", "CFAP20", "CHCHD3", "CHCHD4", "CHEK1", "CHKA", "CHMP1A", "CHMP5", "CHORDC1", "CHST14", "CHUK", "CIRBP", "CLASP2", "CLCC1", "CLCN3", "CLN5", "CLNS1A", "CLPP", "CLPTM1", "CLU", "CLUH", "CMBL", "COA3", "COG3", "COLEC12", "COMT", "COPS2", "COPS3", "COPS4", "COPS5", "COPS7A", "COPS8", "COQ8A", "CORO1C", "COX11", "COX15", "COX5A", "COX7A2", "COX7A2L", "CPD", "CPNE1", "CPT1A", "CPT2", "CPVL", "CRK", "CRTAP", "CSK", "CSNK1A1", "CSNK2B", "CSTB", "CTNNB1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CYB5B", "CYFIP1", "CYFIP2", "CYP51A1", "DBNL", "DCPS", "DCTPP1", "DCUN1D5", "DDX17", "DDX3X", "DDX5", "DERL1", "DHCR24", "DHCR7", "DHFR", "DHRS4", "DHRS7", "DHX33", "DHX9", "DIABLO", "DNA2", "DNAJC1", "DNAJC2", "DNM1L", "DNM2", "DOCK7", "DOLPP1", "DPP9", "DSP", "DUSP12", "DVL2", "DYM", "EBP", "ECE1", "EEF1E1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF3A", "EIF4E", "EIF5", "EMD", "EPDR1", "EPHX1", "ERAP1", "ERC1", "ERCC2", "ERGIC3", "ERLIN2", "ERMP1", "ETFDH", "EXO1", "EXOC1", "EXOC5", "EXOSC2", "EXOSC6", "EXOSC8", "EXTL3", "EZR", "FABP5", "FAM118B", "FAM162A", "FAM208A", "FAM49B", "FAM98A", "FANCA", "FASN", "FASTKD2", "FDFT1", "FGFR1OP", "FHOD1", "FIS1", "FKBP10", "FKBP14", "FKBP1A", "FKBP2", "FKBP4", "FKBP5", "FKBP7", "FLOT1", "FMR1", "FNDC3A", "FNTB", "FOXRED1", "FTO", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "GAA", "GALNT2", "GBA", "GBE1", "GDAP1", "GFPT1", "GGCX", "GGH", "GGT7", "GHITM", "GIGYF2", "GLA", "GLG1", "GLMN", "GLUD1", "GM2A", "GMPPB", "GNPAT", "GOLGA2", "GOLPH3", "GOLPH3L", "GPAM", "GPD2", "GPR107", "GPR108", "GPR89B", "GPS1", "GRB2", "GSK3A", "GSTA4", "GSTM2", "GSTO1", "GTF2B", "GUSB", "HACD3", "HACL1", "HADH", "HCCS", "HDGF", "HDGFL2", "HEBP1", "HELLS", "HEXIM1", "HIP1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HMCES", "HMGB1", "HMGB2", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HOXD13", "HPS6", "HS2ST1", "HSD17B12", "HSD17B4", "HSP90AA1", "HTT", "IARS2", "ICMT", "IDE", "IDH1", "IDH2", "IFNGR1", "IGF2R", "ILVBL", "IMMT", "IMPAD1", "INA", "INTS13", "IPO7", "IPO8", "IQGAP2", "ITCH", "ITGB1", "JAGN1", "JUP", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA1211", "KIAA1468", "KIF14", "KIF3A", "KIF5B", "KLC1", "KLC2", "KMT2A", "KPNA2", "LAMC1", "LAMP1", "LAMTOR2", "LBR", "LDLRAP1", "LETM1", "LGALS3BP", "LIMA1", "LMAN1", "LMF2", "LNPEP", "LPCAT1", "LPGAT1", "LRPAP1", "LSM6", "LSS", "LTA4H", "LZTS2", "M6PR", "MAIP1", "MAN1A2", "MAP2K3", "MAPK1", "MAPK14", "MAPRE2", "MARC1", "MBOAT7", "MCU", "MFN2", "MGAT1", "MGEA5", "MIA2", "MIF", "MINDY3", "MIPEP", "MKRN2", "MLEC", "MMGT1", "MOGS", "MOV10", "MPC2", "MPP2", "MPST", "MPV17L2", "MRC2", "MRPL2", "MRPL43", "MRPL55", "MRPS5", "MSI1", "MSMO1", "MSTO1", "MTAP", "MTBP", "MTCH2", "MTFP1", "MTMR2", "MTOR", "MTR", "MYH14", "MYO18A", "NAA10", "NAA35", "NAA40", "NAGLU", "NAMPT", "NASP", "NCLN", "NCOA5", "NCSTN", "NDC1", "NDC80", "NDUFA11", "NDUFA13", "NDUFAF2", "NDUFB1", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS2", "NEFL", "NENF", "NISCH", "NLN", "NNT", "NOP9", "NPC1", "NPC2", "NPEPPS", "NPTN", "NRDE2", "NSD2", "NSUN2", "NT5C3A", "NT5C3B", "NTMT1", "NUCB1", "NUCB2", "NUDT12", "NUDT16L1", "NUF2", "NUP62", "NXN", "OCIAD1", "OLA1", "OPA1", "OPA3", "OSBP", "OSBPL3", "OTUB1", "OXA1L", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PABPC1", "PAFAH1B1", "PAK2", "PAK4", "PAPSS1", "PCM1", "PCNT", "PCYOX1", "PDCD5", "PDCD6", "PDCL3", "PDE12", "PDE6D", "PDK3", "PEBP1", "PECR", "PELP1", "PEX19", "PEX5", "PFDN1", "PFDN2", "PFN1", "PFN2", "PGGT1B", "PGRMC1", "PGRMC2", "PHB", "PHB2", "PHF2", "PI4KA", "PI4KB", "PIGL", "PIGT", "PIP4K2B", "PIR", "PITRM1", "PLA2G15", "PLAA", "PLD3", "PLK1", "PLOD3", "POGZ", "POLA2", "POLDIP2", "PON2", "POR", "PPAT", "PPHLN1", "PPIF", "PPP2R1A", "PPP2R1B", "PPT1", "PPT2", "PQBP1", "PRCP", "PRDX3", "PRDX4", "PREP", "PREPL", "PRIM2", "PRKAA1", "PRKAA2", "PRKCD", "PRMT1", "PRMT5", "PRMT9", "PRPF39", "PSAP", "PSIP1", "PSMA1", "PSMA6", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC6", "PSMD10", "PSMG1", "PTDSS1", "PTGES3", "PTGR1", "PTPN1", "PTPN11", "PTPRF", "PUF60", "PUS7", "PXMP2", "PYM1", "QKI", "RAB11B", "RAB13", "RAB14", "RAB34", "RAB5B", "RAB5C", "RAB6A", "RAB8B", "RABEPK", "RABGGTB", "RAC1", "RACK1", "RAD23A", "RALA", "RANGRF", "RAVER1", "RBM10", "RBM14", "RBM15B", "RBM3", "RBM4", "RBM47", "RBMX", "RBPMS", "RCC2", "RDH11", "RDH13", "RDH14", "RDX", "REEP3", "REEP4", "REPS1", "RHOA", "RHOG", "RIOX1", "RIPK1", "RNF14", "RNF20", "RNF40", "ROCK1", "RPS28", "RPS3", "RREB1", "RRM2", "RRM2B", "RTN1", "RTN3", "RTN4", "SAMHD1", "SAMM50", "SAR1A", "SAR1B", "SASS6", "SCARB1", "SCARB2", "SCCPDH", "SCO1", "SCP2", "SCPEP1", "SEC11A", "SEC16A", "SEC23IP", "SEC61A1", "SEC62", "SEC63", "SEL1L", "SERBP1", "SET", "SF3A2", "SF3B5", "SFPQ", "SFXN2", "SFXN4", "SGPL1", "SHMT1", "SHMT2", "SIGMAR1", "SIN3A", "SLC12A2", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A20", "SLC25A24", "SLC25A26", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC35F2", "SLC38A2", "SLC6A15", "SLIT2", "SLU7", "SMC2", "SMC4", "SNAP23", "SNAP29", "SNRNP70", "SNRPC", "SNX12", "SNX27", "SNX4", "SNX5", "SNX6", "SNX9", "SOAT1", "SORT1", "SPAG9", "SPART", "SPDL1", "SPHK2", "SPPL2A", "SPR", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRI", "SRP19", "SRPK1", "SRPK2", "SRPRB", "SRSF1", "SRSF6", "SRSF9", "SSBP1", "SSR1", "STAM", "STAMBP", "STK4", "STOML2", "STX12", "STX18", "STX4", "STX6", "STX7", "STXBP3", "SUN1", "SUN2", "SUPT5H", "SUPT6H", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "TACO1", "TAF15", "TAP1", 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1.893158762220583 0.772882004264421 1.343874754683687 0.2717215815078918 0.0078467631279172 1.0 0.0115435449528709 0.0630532374058985 0.0472723399635447 +Lysosomal lumen 25 37 2.3259484814548173 0.0200212992287316 18.075242718446603 34.54368932038835 0.7848519845050315 0.1014568164283454 6.206531846566726 3.2976210873168883 3.038689298289951 0.2012423645269794 1.0 1.0 0.4860789703868964 0.0002293262711536 7.028181452059654e-07 +Sarcoplasmic reticulum membrane 0 9 2.269894838615646 0.0232139643586866 2.8276699029126213 8.800970873786408 0.2185084048814107 0.4771108976572529 1.746539270963151 1.1841178065269469 0.986524173093179 0.2963332947904156 0.1475747309757272 0.0937235599037543 0.1774332758731671 0.3891747515056749 0.255405515221392 +Endoplasmic reticulum lumen 15 63 2.223116989471789 0.0262079123243104 18.07766990291262 59.737864077669904 0.9896277047863468 0.3946249358858228 7.513340007333169 6.273245958458151 1.4320597420402308 0.3846324865730224 0.1508618931598255 0.2008803863342955 0.081976144819797 0.0027759808455764 0.0036786287352893 +Copi coated vesicle 3 14 2.1092238212736185 0.0349252666719219 3.366504854368932 13.565533980582524 0.927757948703832 0.3021632050419245 1.9356503178232003 1.3008870969982682 1.2180478421179144 0.2957691490409697 0.0107949235467619 0.0042324529563037 0.0158256043387446 0.0119341177484456 0.0145952588649919 +Golgi membrane 47 142 2.080487546002121 0.0374808367697603 41.28398058252427 131.19174757281553 1.6327747521284677 0.3511039607499193 15.277988344159814 17.44963987873233 1.926180921267262 0.4033858283713009 0.4385028843000782 0.3465659246385915 0.396467785287477 0.0077394997559257 0.009675091157388 +Envelope 122 495 2.0754708565973408 0.0379429171504859 133.55825242718447 476.99271844660194 1.1125762168925015 0.4931727688685032 47.82674034566458 40.415168802184624 2.6300132137901633 0.4489464989697134 5.966127424194467e-06 0.0007505669324719 1.8994861686086648e-05 1.5983352403117809e-07 2.164766642190544e-11 +Tim23 mitochondrial import inner membrane translocase complex 1 5 2.075466615180029 0.0379433098623507 2.2694174757281553 6.342233009708738 1.5180442383336388 0.125307709046494 1.369833329272529 0.8106469094037756 1.2674744491900518 0.2021471972412396 0.0840370854942358 0.0526645480715484 0.1018169846714528 0.0280420066437826 0.0978216105640502 +Copi coated vesicle membrane 3 13 2.0710964059490653 0.0383497876672842 2.9611650485436893 12.451456310679612 0.9351146201256926 0.2894293018559171 1.7580457491925867 1.2208038158644114 1.2401568068418547 0.2855671555488221 0.0069592764782258 0.0027067874988798 0.0102498345034834 0.0062969264366488 0.0063986173037271 +Calcium channel complex 0 8 2.0707475579046437 0.0383823933360247 2.4150485436893203 7.298543689320389 0.1538765288718164 0.4525613292140901 1.4615016707365889 1.3130036030733032 1.08449347730351 0.3081575616966512 0.1677707747748128 0.1070183553885475 0.2012104780589677 0.4327587673805496 0.6843179386047307 +Outer mitochondrial membrane protein complex 5 16 2.038312714728787 0.0415186691193889 7.157766990291262 15.730582524271844 1.3245491566248977 0.2112996285983387 3.5767402396348245 0.8689557679680192 1.477430451036954 0.2853006280851536 0.1475747309757272 0.0937235599037543 0.0158256043387446 0.0840389641709933 0.0022923961599421 +Golgi cisterna 11 26 2.020664376976792 0.0433145198297928 8.524271844660195 22.490291262135923 0.9086972174309816 0.318868202549777 4.2525712614684625 5.269200019661922 1.391079392561209 0.3149122340418913 0.4425168834427829 1.0 0.5107150602013826 0.0322116961133286 0.1454895561901762 +Golgi cisterna membrane 4 20 2.003236357158925 0.0451519249687906 6.233009708737864 17.101941747572816 0.7930989258143627 0.3092897028410761 3.2184356191878685 3.952300069740005 1.3504727992091758 0.2953094162507478 0.3401863269772942 1.0 0.3986935444378103 0.0372180748890915 0.1086169414893013 +Cytoplasmic stress granule 18 49 1.9613286531143832 0.0498406968883917 16.961165048543688 44.01699029126213 0.1060948640769821 0.6180155726882541 8.213087271310163 2.534653548624787 0.9910975835660816 0.3478412307977345 1.0 1.0 1.0 0.2487153672879259 0.0022266246185573 diff --git a/msigdb_gocc/metrics.json b/msigdb_gocc/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..ee7fec9ed122bae30e8ec514e4297ebd6f3a328d --- /dev/null +++ b/msigdb_gocc/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3329, + "annotations_size": 906, + "title": "Average number of proteins per term", + "value": 29.958057395143488 +} \ No newline at end of file diff --git a/msigdb_gocc/paths.json b/msigdb_gocc/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..7eca050f6f3bcae4ec049f379d20ce0f9e45f3a8 --- /dev/null +++ b/msigdb_gocc/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gocc/fragment/C342/C342_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gocc/result.tsv b/msigdb_gocc/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..6969720ca44c4dd29c465497f4197dc82d43d013 --- /dev/null +++ b/msigdb_gocc/result.tsv @@ -0,0 +1,256 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Endoplasmic reticulum 0.4823046844965288 4.98670689392632 6.141713191553512e-07 0.0005562846023456 0.0005564392151556 481 P62942,P37268,P30519,Q15392,Q5BJF2,O43731,O94888,Q96AY3,Q14739,P24390,P26885,Q32P28,Q9UMX5,P80303,P09601,O75503,O60725,Q9UQB8,Q8TCT8,P48449,Q02818,Q15629,Q9NZ08,P10619,O95470,Q8N2K0,P07099,Q9Y282,Q15125,Q16799,Q86XL3,Q03518,O15173,Q15363,P43307,O75844,O95197,Q99523,Q9HD20,Q06136,Q14257,Q14108,Q07065,Q96G23,Q92791,Q9Y680,Q15800,Q9H0P0,Q9NWM8,O43909,P04062,Q16850,Q99720,Q15041,P13674,P30536,Q9BRR6,Q9H2J4,Q9NZ01,P49257,Q9BU23,O15270,P35613,Q9P2W9,P38435,Q9UBM7,Q9BTY2,Q8N0U8,O15460,O95674,P11047,Q86YN1,Q01105,Q8IV08,Q96S66,O60506,Q86YV9,P10321,P42858,Q5VV42,O95881,O43390,Q8IUR0,Q8N511,P62857,Q9BVK6,P67812,Q969V3,O75718,O15027,O95456,Q8N5M9,P28482,O60476,Q9P035,P51648,O43852,O15118,Q9Y6Y8,A1L0T0,Q9H4L5,Q92734,Q8N2F6,Q6NUK4,Q13510,P84157,Q7Z2K6,Q96PC5,Q9BUN8,Q9Y2B2,Q9UBF8,P52789 112 +Organelle subcompartment 0.5056001705083792 2.926713710933387 0.0034256405804353 0.95535256850387 0.409520919038946 371 P62942,P37268,P30519,Q15392,Q5BJF2,O43731,O94888,Q14739,P24390,P26885,Q9NPR9,P09601,O60725,Q8NBN3,Q8TCT8,P48449,Q15629,Q7Z6M1,Q9NZ08,O95470,Q8N2K0,P07099,Q9Y282,Q15125,Q16799,Q86XL3,Q03518,O00461,Q15363,P43307,O75844,O95197,Q99523,Q9BXS4,Q9HD20,Q06136,Q14108,Q07065,Q96G23,Q15800,O43909,O43752,P04062,Q16850,Q99720,Q15041,Q9BRR6,Q9NZ01,P49257,Q9BU23,Q9HC07,O15270,P35613,Q9P260,Q9P2W9,P38435,Q9UBM7,Q8N0U8,Q96JB2,O95674,Q92614,Q86YN1,Q8IV08,P53365,Q96S66,P10321,Q4J6C6,Q5VV42,Q8N511,P62857,Q9BVK6,P67812,Q969V3,O15027,P20645,Q8N5M9,Q9P035,P51648,O43852,A1L0T0,Q9H4L5,Q8N2F6,Q6NUK4,Q7Z2K6,Q96PC5,Q9BUN8,Q9Y2B2 87 +Intrinsic component of mitochondrial inner membrane 0.6564688243769845 2.797866386589813 0.0051441387575874 0.990652238195072 0.409520919038946 32 Q9Y512,Q5XKP0,Q99595,Q15070,Q9Y2R0,Q9BUR5,Q96ER9,Q9NX63,Q9Y6N1,O14925,O95563,Q6P4A7,Q16134,Q9H3K2,O75880 15 +Intrinsic component of mitochondrial membrane 0.5810867093736015 2.786087427849832 0.0053348480930899 0.9921426907350216 0.409520919038946 48 Q9Y2R0,P12235,Q96ER9,Q9Y6N1,Q9UH62,Q16134,Q99595,Q9BUR5,O75880,Q96NB2,Q15070,P57105,Q9NX63,Q9Y512,O95563,Q5XKP0,O14925,Q6P4A7,Q9H3K2,O95140 20 +Cis golgi network 0.7824374636888387 2.7568545080397757 0.0058360312400049 0.9950230271852998 0.409520919038946 15 Q9NPR9,O43731,P24390,O00461 4 +Intrinsic component of organelle membrane 0.5445064175811718 2.709124050203388 0.0067461111325646 0.9978292573033544 0.4101130661766353 127 Q86Y82,Q9Y2R0,O75844,Q86YN1,P12235,Q9P035,Q96ER9,Q9NQ11,Q9Y6N1,O15118,Q9UH62,Q16134,Q14739,Q99595,P10321,Q9BUR5,O43505,P57088,O43752,O75880,Q96NB2,Q15070,Q15041,Q8TCT8,P57105,Q15629,Q9BUN8,Q9NX63,P42892,Q9NZ01,O95470,O95563,Q9Y512,Q9Y282,O95070,Q15125,O94901,Q5XKP0,Q16799,Q86XL3,Q9UBM7,Q03518,Q96A33,O14925,Q6P4A7,Q9H3K2,P61020,P04439,P01889,O95140 50 +Proteasome core complex 0.7596897882480271 2.64172432339084 0.0082485163946228 0.9994492048626784 0.4101130661766353 15 P28070,P25786,P20618,P28074,P49721,P28072 6 +Intrinsic component of endoplasmic reticulum membrane 0.5499247961925013 2.5862455252045886 0.0097027787474039 0.9998542536281804 0.4101130661766353 52 Q9Y282,Q15125,Q15041,O75844,Q8TCT8,Q16799,Q86YN1,Q15629,Q9UBM7,Q86XL3,Q03518,Q9NZ01,O95470 13 +Endoplasmic reticulum golgi intermediate compartment 0.5505813885265978 2.5655123760862515 0.0103023546012073 0.9999158026253068 0.4101130661766353 50 Q8N511,Q9Y282,Q92614,Q02818,P80303,Q03518,Q15363,Q8IUR0,P24390,P49257 10 +Golgi associated vesicle membrane 0.6710671099966047 2.4834785721199637 0.0130106161798633 0.999992967526232 0.4106285635751545 20 Q8TCT8,Q15363,O43731,P42356,P24390 5 +Golgi associated vesicle 0.6128815873405438 2.480484502579223 0.0131203967097961 0.9999936417024732 0.4106285635751545 31 Q8N511,Q8TCT8,Q99523,O43731,Q15363,P42356,P24390 7 +Endoplasmic reticulum golgi intermediate compartment membrane 0.6276820257812198 2.45940238695644 0.0139168537169058 0.9999969404067468 0.4106285635751545 26 Q8N511,Q9Y282,Q03518,Q15363,P49257,P24390 6 +Proteasome core complex beta subunit complex 0.8941095666428472 2.399641601636236 0.0164111310806109 0.999999691591475 0.4106285635751545 7 P49721,P28070,P28074,P28072 4 +Proton transporting two sector atpase complex proton transporting domain 0.8079673287917679 2.398081290773583 0.0164812071503059 0.9999997108704792 0.4106285635751545 10 P00846,O75964,Q9Y487 3 +Nuclear outer membrane endoplasmic reticulum membrane network 0.5166755471734646 2.391720681263661 0.0167695991747027 0.9999997783334552 0.4106285635751545 301 P62942,Q9H6H4,P37268,P30519,Q15392,Q96JJ7,Q5BJF2,O43731,O94888,Q04323,Q14739,P50402,P24390,O00264,Q14534,P26885,P09601,O60725,Q8TCT8,P48449,Q15629,Q9NZ08,O95470,Q8N2K0,P07099,Q9Y282,Q15125,Q16799,Q86XL3,Q03518,Q15363,P43307,O75844,O95197,Q99523,Q9HD20,Q06136,Q14108,Q07065,Q96G23,Q15800,O43909,Q16850,Q99720,Q15041,Q9BRR6,Q9NZ01,P49257,Q9BU23,O15270,P35613,Q9P2W9,P38435,Q9UBM7,Q8N0U8,O95674,Q86YN1,Q8IV08,Q96S66,P10321,Q5VV42,Q8N511,P62857,Q9BVK6,P67812,Q969V3,O15027,Q8N5M9,Q9P035,P51648,O43852,A1L0T0,Q9H4L5,Q8N2F6,Q6NUK4,Q7Z2K6,Q96PC5,Q9BUN8,Q9Y2B2,Q9UBF8,O75340,P16615,Q9Y5M8 83 +Pore complex 0.803828765940363 2.3429805555291248 0.0191303800703432 0.9999999748913786 0.4333031085932755 9 P21796,P45880 2 +Lysosomal lumen 0.565574483616594 2.3259484814548173 0.0200212992287316 0.9999999889776848 0.4424218805178259 37 P50897,P46976,Q8NHP8,Q8IV08,Q9NQ11,P07602,Q14108,P08236,P04066,P17900,P61916,Q9UMR5,Q13510,P04062,O43681,Q9NZJ7,P07858,P10619,P10253,P06280,O14773,P38435,Q9UM22,P11117,P54802 25 +Endoplasmic reticulum lumen 0.4876877648082485 2.223116989471789 0.0262079123243104 0.9999999999644849 0.4959082485152252 63 Q07065,Q32P28,P11047,Q9Y680,Q02818,P13674,P28482,Q9BTY2,O75718,Q96AY3,Q14257,Q9NWM8,O95881,Q9NZ08,O15460 15 +Copi coated vesicle 0.6692160484080534 2.1092238212736185 0.0349252666719219 0.9999999999999896 0.5375747255587988 14 O43731,Q15363,P24390 3 +Golgi membrane 0.4913485464211095 2.0804875460021215 0.0374808367697603 0.9999999999999992 0.5375747255587988 142 Q86Y82,Q16739,Q92614,O95197,Q9BXS4,Q15392,Q8IV08,Q8NCH0,O43731,P11717,Q96S66,P15291,P24390,Q14108,Q8IZA0,P51790,P10321,Q9BUR5,O43505,Q7LGA3,P26572,O43752,O95721,Q8NBN3,Q9H4A6,Q8N4V1,Q9BVK6,Q12907,Q9UBF8,Q9H7Z7,P49257,Q9HC07,P35613,Q96JB2,Q9Y282,O95070,Q7Z3C6,O15027,Q9P2W9,P78536,Q16799,O00461,Q15363,P0CG08,P04439,P01889,O60476 47 +Envelope 0.3417386559903661 2.0754708565973408 0.0379429171504859 0.9999999999999994 0.5375747255587988 495 Q8N183,Q96ER9,Q9NS69,Q9Y6N1,Q5BJF2,Q96AY3,Q8N0X7,Q9NQ50,P00846,Q14739,Q70HW3,Q7Z7H8,Q567V2,P50402,O00264,Q99595,Q9HB71,Q9Y619,Q9BUR5,Q7Z7F7,O43772,P80303,Q69YU5,Q9NVS2,Q8N4Q1,P09601,P14406,P57088,P0DP25,O43169,P82912,P21796,Q9HD42,Q9BSK2,P45880,Q9H4A6,Q9H2D1,Q96NB2,Q8IUX1,Q6NUK1,P57105,P23786,Q9NZZ3,Q8N4H5,O95563,Q13084,O94901,Q15125,Q9NRA0,Q9NR28,Q96KC8,O95831,O75964,Q02978,O15173,Q96A26,P53701,Q9Y2R0,O75844,Q99523,Q96CU9,Q5T653,O14949,O95373,O43676,Q9UDW1,Q6DKK2,Q99720,Q15070,P30536,Q9UDX5,O60313,Q9UBM7,O75306,O14925,Q9BTX1,O95140,O95674,Q9H061,P12235,Q9NPL8,P34897,Q96S66,Q15007,Q9BUK6,P67809,O75880,Q9H1E5,Q8NI60,P82675,P62995,Q9BYT8,Q9NQZ5,Q5XKP0,P20674,Q8N983,Q6P4A7,Q9H3K2,Q86Y39,Q9Y6C9,Q9UBX3,Q9P035,O15118,O15397,O75438,O95168,Q16134,Q8WWC4,Q9H4L5,Q9BXK5,Q99543,Q9Y6M9,Q9UBF8,Q9NX63,Q96TA2,P52789,Q9Y512,Q9BRJ2,Q7KZN9,P82933,Q9H8M7,O15228 122 +Tim23 mitochondrial import inner membrane translocase complex 0.8922169027052604 2.075466615180029 0.0379433098623507 0.9999999999999994 0.5375747255587988 5 Q99595 1 +Copi coated vesicle membrane 0.6852533882891347 2.0710964059490653 0.0383497876672842 0.9999999999999996 0.5375747255587988 13 O43731,Q15363,P24390 3 +Outer mitochondrial membrane protein complex 0.6351468135844763 2.038312714728787 0.0415186691193889 1.0 0.5375747255587988 16 Q5XKP0,Q9NX63,Q9NS69,Q8N4H5,Q9Y512 5 +Golgi cisterna 0.5608266924026662 2.0206643769767916 0.0433145198297928 1.0 0.5375747255587988 26 Q9BZG1,Q9H4A6,Q99523,Q9BXS4,O00461,Q15363,P0CG08,P04439,Q96JB2,P15291,Q8NBN3 11 +Golgi cisterna membrane 0.5908372879796766 2.003236357158925 0.0451519249687906 1.0 0.5454352536229906 20 Q99523,Q15363,O00461,Q8NBN3 4 +Cytoplasmic stress granule 0.480340710694024 1.9613286531143832 0.0498406968883917 1.0 0.5674707652514943 49 Q7Z739,O00571,Q93062,Q14157,P61978,Q9BWF3,P11940,Q9Y5A9,Q14011,Q6Y7W6,Q13310,Q9HCE1,P06730,Q9BYJ9,P67809,O60828,Q06787,Q01085 18 +Vacuolar lumen 0.4459736699558596 1.945942476450901 0.0516616498285422 1.0 0.5674707652514943 69 P50897,Q8NHP8,Q8IV08,Q9NQ11,P07602,Q14108,P17900,Q92820,Q9BRF8,Q9UMR5,Q13510,P04062,P07858,P10619,P06280,P38435,Q9BTY2,Q9UM22,Q01469,P28482 20 +Microbody 0.4650452463112593 1.898675634790088 0.0576071370334247 1.0 0.5674707652514943 56 Q8N4Q0,Q5T8D3,O75874,Q96CN7,Q15067,Q9NR77,P48735,Q9BQG2,P08670,Q9BY49 10 +Copii coated er to golgi transport vesicle 0.5274672053326295 1.8856502761438945 0.0593420976000844 1.0 0.5674707652514943 31 Q9Y282,O95070,O15027,Q9BVK6,Q12907,P10321,P49755,P01889,Q15363,P04439,P49257,O75340,Q9Y6Y8 13 +Proton transporting atp synthase complex coupling factor f o 0.770080230939594 1.8841500321518432 0.0595446842359401 1.0 0.5674707652514943 7 P00846 1 +Intrinsic component of plasma membrane 0.4308112219832233 1.86966545158384 0.0615302900019758 1.0 0.5674707652514943 79 Q9UJS0,O96005,P15260,P12235,Q9UIQ6,Q8WTV0,O15118,Q99996,P11717,O00264,P53985,P10321,P10586,Q9H1Z9,Q99797,P41440,P0DP25,O15111,Q8N2K0,Q9Y639,P35613,Q9NR28,P78536,P02786,Q96QD8,Q02978,Q9H813,P20645,O43657,P04439,P01889,P16615,Q99805 33 +Nuclear inner membrane 0.5635681580370739 1.833574863993489 0.0667171262677015 1.0 0.5674707652514943 20 Q99720,Q14739,Q9H1E5,O75844 4 +Dendrite cytoplasm 0.6793984412375547 1.8321572169123588 0.0669280008742294 1.0 0.5674707652514943 11 Q9UQB8 1 +Secretory granule membrane 0.4343487067010041 1.827162216151312 0.0676753829930325 1.0 0.5674707652514943 69 Q13576,P20073,P30519,Q14165,Q96JJ7,P07602,P42785,Q9Y2Q5,P15291,O00264,Q07065,Q93050,P10321,Q969Q5,O95721,P51148,P35613,Q01469,Q15363,P61020,P01889 21 +Mitochondrial permeability transition pore complex 0.825941854352094 1.8133089793372392 0.0697841791423852 1.0 0.5695897865135225 5 P21796 1 +Proton transporting two sector atpase complex 0.5428310010001831 1.7909740753184544 0.0732974552992107 1.0 0.5810510663962899 23 P00846,O75964,Q93050,Q9Y487 4 +Inner mitochondrial membrane protein complex 0.4225459761677658 1.780617410625239 0.0749749735289311 1.0 0.5810510663962899 79 Q5XKP0,Q99595,O43676,P20674,O75964,Q9Y6M9,Q96CU9,Q9UDW1,O75306,O14925,Q9NX63,O75438,O95168,Q86Y39,P00846,P14406,O14949 17 +Transport vesicle 0.4328019634346477 1.7706827379695511 0.0766134745866651 1.0 0.5832925039959546 93 P50897,Q86Y82,O15400,Q99523,Q9NQ11,O43731,Q96A57,P11717,Q92542,P24390,Q9Y6Y8,P51790,O15498,P10321,Q9BT78,O43752,P0DP25,Q9BVK6,Q7Z6M1,Q92905,P49257,O75340,O15027,P01889,P20645,O00461,Q15363,O76024,P61020,P04439,O00429 31 +Anaphase promoting complex 0.67436433974819 1.7454521967952474 0.0809061865970417 1.0 0.6008279103026215 9 Q96DE5,O60566,Q9UJX6,Q9UJX3,Q16763 5 +External side of plasma membrane 0.5281261491940338 1.7259791967109244 0.0843511554117288 1.0 0.602715893132923 24 P17655,P08183,O96005,P02786,P42892,P07858,P04083,P41440,P49327,P15291 10 +Centriolar satellite 0.5121406001712698 1.7180501785601272 0.0857874631022945 1.0 0.602715893132923 28 Q86UY6,Q9Y5A9,Q03518,P41440 4 +Coated vesicle 0.4284216169833382 1.7147532715195106 0.0863904721103729 1.0 0.602715893132923 94 Q99523,O43731,Q9P253,Q9Y6Y8,Q14108,P24390,P10321,O43752,Q8N511,Q9BVK6,Q5VW38,P42892,P49257,O75340,Q9Y282,O15027,O14641,P20645,Q15363 19 +Extrinsic component of organelle membrane 0.6538973599138438 1.707111530142258 0.087801324428671 1.0 0.6035837814462305 11 P62942,P04083,Q8NI60 3 +Caveola 0.5725224472934372 1.6789442544073865 0.0931629086147192 1.0 0.6224571729941006 16 P09601,Q8WTV0 2 +Er to golgi transport vesicle membrane 0.5336819325561564 1.6439355489280791 0.1001895161616408 1.0 0.6329184707714659 20 O15027,P10321,Q15363,P04439,P49257,O75340,Q9Y6Y8 7 +Dendritic shaft 0.7742574266866744 1.6045750304295452 0.1085873601623776 1.0 0.6329184707714659 5 Q9UQB8 1 +Messenger ribonucleoprotein complex 0.772870546898971 1.5989289063188084 0.1098364002850651 1.0 0.6329184707714659 5 Q99729,P51991,P67809 3 +Platelet alpha granule lumen 0.6132244801286271 1.5935936599717124 0.1110270754368711 1.0 0.6329184707714659 12 Q9NTK5 1 +Golgi stack 0.4724524563034813 1.5871392697839786 0.1124811055712742 1.0 0.6329184707714659 36 Q9BZG1,Q9H4A6,Q99523,Q9BXS4,O00461,Q15363,P0CG08,Q99996,P04439,Q96JB2,P15291,Q8NBN3 12 +Golgi apparatus subcompartment 0.4154363128455418 1.5719865375533388 0.1159536733959578 1.0 0.6366910793741687 94 P04062,Q9P260,Q92614,Q9NPR9,Q99523,Q7Z6M1,Q9BXS4,O00461,P53365,Q15363,Q96JB2,O43752,Q9HC07,Q8NBN3 14 +Proton transporting atp synthase complex 0.6069806722347344 1.5611501134539956 0.1184883363326165 1.0 0.6370031490319358 12 P00846 1 +Proteasome complex 0.4322906718584213 1.539170121016442 0.1237627699314767 1.0 0.6451461436428673 50 P28070,P25786,Q8IWV7,P20618,P54725,P28074,P49721,P28072 8 +Outer membrane 0.4077524177383058 1.538258813851395 0.1239853457058148 1.0 0.6451461436428673 88 Q9NS69,Q8N0X7,P50402,O00264,Q9BUK6,P09601,O43169,P21796,Q99720,P45880,Q9UBF8,Q9NX63,P30536,P52789,Q8N4H5,Q9Y512,Q9NQZ5,O60313,Q5XKP0,Q9UBM7,O95140,Q9Y6C9 22 +Platelet alpha granule 0.5476395865624439 1.532290933584468 0.1254506574177236 1.0 0.6451461436428673 16 Q9NTK5 1 +Organelle envelope lumen 0.4511917285774031 1.5094940848203582 0.1311725657964628 1.0 0.6451461436428673 40 Q9H4A6,Q9HB71,Q9NR28,O95831,Q9BYT8,P52888,Q8N4Q1,O14925,Q96AY3,P11717,P36404,O60313 12 +Proton transporting v type atpase v0 domain 0.9318658949064118 1.5061626433626465 0.1320254266498337 1.0 0.6451461436428673 3 Q9Y487 1 +Vacuolar proton transporting v type atpase v0 domain 0.9318658949064118 1.5061626433626465 0.1320254266498337 1.0 0.6451461436428673 3 Q9Y487 1 +Side of membrane 0.3959867132284315 1.498524011916024 0.1339971588059756 1.0 0.6451461436428673 78 P62942,O96005,Q5SW96,P15291,P17655,P17900,P10321,Q9Y5X3,P41440,O15111,P08183,P62857,Q8TCT8,P31749,P42892,P07858,P49327,P10619,Q9NR28,P02786,P04083,P04439,P01889 23 +Organelle inner membrane 0.4613543972836043 1.4962994657366997 0.1345756342830255 1.0 0.6451461436428673 242 Q8N183,P53701,Q9H061,Q9Y2R0,O75844,Q9UBX3,P12235,Q96CU9,Q96ER9,Q9NPL8,Q9Y6N1,P34897,O75438,O95168,Q16134,Q9NQ50,P00846,Q8WWC4,Q14739,Q7Z7H8,Q70HW3,P50402,Q567V2,Q5T653,O14949,Q99595,O43676,Q9Y619,Q9BUR5,Q7Z7F7,O43772,Q9UDW1,Q69YU5,Q9NVS2,P14406,Q6DKK2,O75880,P82912,Q9BSK2,Q96NB2,Q8IUX1,Q9H2D1,Q99720,Q15070,Q9H1E5,Q8NI60,P82675,P23786,P62995,Q9Y6M9,Q9NX63,Q96TA2,Q9UDX5,O95563,O60313,Q9Y512,Q9BRJ2,Q5XKP0,Q7KZN9,P82933,P20674,O95831,O75964,Q02978,Q8N983,O75306,O14925,Q6P4A7,Q9H3K2,Q86Y39,Q9Y6C9,O95674 72 +Chromocenter 0.7446743093131315 1.4837070175705835 0.137886663758838 1.0 0.6506526946120171 5 Q53HL2 1 +Protein phosphatase type 2a complex 0.7145318020696211 1.473374456281806 0.1406500940500463 1.0 0.651558741910031 6 P30154 1 +Coated vesicle membrane 0.4170190474857693 1.468269125537191 0.1420311339668885 1.0 0.651558741910031 58 Q8N511,Q9Y6Y8,O15027,P10321,P02786,P04439,P01889,P20645,Q5SW96,O43731,Q15363,P24390,P49257,O75340,Q14108 15 +Integral component of lysosomal membrane 0.8800721370604166 1.4611708937678456 0.1439685485692918 1.0 0.651558741910031 2 Q9NQ11 1 +Intrinsic component of golgi membrane 0.6093646182136805 1.4568968147954104 0.1451448654230982 1.0 0.651558741910031 10 Q9Y282 1 +Specific granule membrane 0.5335627088885727 1.4484356217504823 0.1474952584833428 1.0 0.6518570935897984 16 P30519 1 +Lumenal side of membrane 0.603985391959098 1.430096394929089 0.1526893547583085 1.0 0.6643028240317761 10 P10619,P04439,Q8TCT8,P10321 4 +Haus complex 0.7041829671983173 1.4299575601567749 0.1527292000643507 1.0 0.6643028240317761 6 Q9NVX0,Q96CS2,O94927,Q9H6D7,Q68CZ6 5 +Azurophil granule membrane 0.4926130799006122 1.426641669537423 0.1536832068258355 1.0 0.6643028240317761 22 P07602,Q07065,P42785 3 +Endoplasmic reticulum protein containing complex 0.4114535652041702 1.4256220228606662 0.1539774757689547 1.0 0.6643028240317761 59 P62942,Q15041,P13674,Q03518,O94888 5 +Plasma membrane raft 0.4951715686730558 1.4181124266674143 0.1561579437866909 1.0 0.6670480147379054 21 P09601,Q8WTV0 2 +Schaffer collateral ca1 synapse 0.5340800517851587 1.4033186295472748 0.1605218453225114 1.0 0.6713355805879718 15 Q16352,P07196,Q9UQB8,Q9Y639 4 +Rough endoplasmic reticulum membrane 0.5255919082709946 1.400689677915883 0.1613068907051162 1.0 0.6713355805879718 16 P62857,Q15041,Q9UBF8,Q5BJF2,Q9Y5M8 5 +Postsynaptic cytosol 0.6547813841032044 1.3790427559323672 0.1678815717092996 1.0 0.6782542841758243 7 Q9UQB8 1 +Mitochondrion 0.3276242782404309 1.3790403607778905 0.1678823101448632 1.0 0.6782542841758243 636 Q16740,Q9H773,Q9NPH0,Q9NR77,Q9NS69,Q96AY3,P48735,P00846,Q70HW3,Q567V2,Q99595,Q9UMX5,Q9Y619,P00374,Q7Z7F7,O43772,Q9NUJ1,Q69YU5,Q8N4Q1,Q9BWD1,P09601,P14406,Q9NUQ9,O43169,P21796,Q9BSK2,P45880,Q9H2D1,P23786,O75874,Q02790,Q8N4H5,O95563,Q9NR28,O95831,O75964,Q02978,Q3SXM5,Q5JRX3,Q96A26,Q9NVH6,Q8TAE8,P28070,P53701,Q9Y2R0,Q16836,Q96CU9,P30153,Q5T653,O14949,O43676,Q9UDW1,Q6DKK2,P51530,Q7LG56,Q15070,P13674,Q9H6K4,P31749,Q9NYY8,P30536,Q9UDX5,O60313,P35613,Q15165,O75306,O14925,Q15120,O95140,O95674,Q5TAQ9,Q9H061,Q9NSE4,P12235,Q9NPL8,P34897,Q9BY49,O43823,Q9BUK6,O75880,Q8NI60,P82675,P11233,Q9BYT8,Q9NQZ5,Q8NBX0,Q5XKP0,P20674,Q8N983,Q6P4A7,Q9H3K2,Q86Y39,P28482,Q9Y6C9,Q04837,Q9UBX3,Q9Y2S7,O75438,O95168,Q16134,Q8WWC4,Q8NFF5,Q68CZ6,O75648,Q9Y237,Q8N2F6,Q9BXK5,Q08J23,Q9Y6M9,Q9UBF8,Q9NX63,Q9BW92,Q96TA2,P52789,P42126,Q9Y512,Q9BRJ2,Q7KZN9,P82933 119 +Microbody membrane 0.4644852535324177 1.373411520081097 0.1696244504428707 1.0 0.6782542841758243 28 Q5T8D3,O00116,Q9NR77,P51648,Q15067,O15228,Q9BY49 7 +Rough endoplasmic reticulum 0.4455770109397562 1.3729802833231446 0.169758476256935 1.0 0.6782542841758243 36 P62857,Q07065,Q15041,Q9UQB8,Q9UBF8,Q5BJF2,Q5VV42 7 +External encapsulating structure 0.4362139096772546 1.3613711747669786 0.1733964206734657 1.0 0.6782542841758243 39 Q5KU26,P11047,P51858,P20073,P50995,O14936,Q13043,P20248,P07602,Q32P28,P53634,Q53GQ0,Q08380,P84157,Q9NZJ7,P07858,P49257,O60568,P04080,P04083,P10909 21 +Endosome lumen 0.8913272687717853 1.3552929981197708 0.1753242249546298 1.0 0.6782542841758243 3 Q9UIQ6 1 +Postsynaptic density membrane 0.6482844103549444 1.3499978200356528 0.1770166821357039 1.0 0.6782542841758243 7 Q14168,Q9Y639 2 +Synaptic vesicle membrane 0.5490150846892997 1.3443833637534028 0.1788244506554608 1.0 0.6807350936716281 13 Q86Y82,O76024,P61020,O00429,O43752,P0DP25 6 +Endocytic vesicle membrane 0.4147955000738707 1.3290413574829374 0.1838343256839718 1.0 0.6910950168866327 45 Q5KU26,Q93050,P10321,P02786,Q8WTV0,Q03518,Q5SW96,P20645,Q9Y487,P04439,P01889,P11717,Q14108 13 +Golgi trans cisterna 0.8373910429816512 1.286228136829298 0.1983634540821242 1.0 0.7160051370454362 2 Q9BXS4 1 +Triglyceride rich plasma lipoprotein particle 0.8343853321310337 1.2739502493573327 0.2026810483530194 1.0 0.7227852535738819 2 Q9UHG3 1 +Peptidase complex 0.392855118185662 1.2522380195093292 0.2104831460664524 1.0 0.7227852535738819 60 P28070,P25786,Q8IWV7,P20618,P60900,P54725,P28074,P49721,P28072 9 +Collagen containing extracellular matrix 0.4353322020038691 1.249366174285064 0.2115311744373558 1.0 0.7227852535738819 34 Q32P28,P11047,P51858,P53634,P20073,O14936,P04080,Q13043,P20248,P07602,Q9NZJ7,P07858,P04083,P10909,P49257,Q08380,P84157 17 +Endopeptidase complex 0.3965463882344401 1.2477320032692494 0.2121292171796374 1.0 0.7227852535738819 56 P28070,P25786,Q8IWV7,P20618,P54725,P28074,P49721,P28072 8 +Postsynaptic specialization membrane 0.5622454460463023 1.2453414913262253 0.2130062502254155 1.0 0.7227852535738819 11 Q14168,Q9Y639 2 +Trans golgi network 0.3831869168720053 1.2352738299476973 0.2167286100094618 1.0 0.7300908399505343 66 Q9P260,Q92614,Q9NPR9,Q7Z6M1,Q4J6C6,P53365,Q96JB2,O43752,Q9HC07,P04062 10 +Myofilament 0.6830720999251734 1.229957200719361 0.2187131323556597 1.0 0.7300908399505343 5 P06753,P67936,P09493 3 +Striated muscle thin filament 0.6830720999251734 1.229957200719361 0.2187131323556597 1.0 0.7300908399505343 5 P06753,P67936,P09493 3 +Micos complex 0.7681203007518811 1.222937779921826 0.2213531976942739 1.0 0.7346007220183598 4 Q9BUR5,Q5XKP0,Q9NX63 3 +Cell surface 0.3748469776087681 1.2044400218608493 0.2284195510530606 1.0 0.744417673575802 84 P14174,Q13576,O96005,Q92614,Q99523,Q8WTV0,Q96JJ7,P11717,P15291,P17655,P51790,P10321,P41440,P08183,Q12907,P11233,P42892,Q9UII2,P07858,P49327,Q9Y639,P78536,P02786,Q9H813,P04083,P04439,P01889,P10909 28 +Neurofilament 0.7584962406015053 1.1857804895333257 0.2357089983833209 1.0 0.758288947303156 4 Q5SW96,Q16352,P07196 3 +Rna cap binding complex 0.6718537374351369 1.183628688689392 0.2365600787957786 1.0 0.758288947303156 5 Q06787,P06730 2 +Neuron projection cytoplasm 0.4213209351478667 1.1762796932322828 0.2394831276950628 1.0 0.761304258567463 36 Q9UQB8,Q9Y2T2,P07196,Q14168,Q99729,Q06787,O60313,Q8N2K0 8 +Neuronal ribonucleoprotein granule 0.8385447985568202 1.159478004045922 0.2462613973322676 1.0 0.7724182030036228 3 Q99729,Q06787 2 +Respirasome 0.3923305216966453 1.1556714404089343 0.247815574236494 1.0 0.7724182030036228 47 O43676,P20674,Q9Y6M9,Q96CU9,Q9UDW1,O75306,O75438,O95168,Q86Y39,Q6DKK2,P14406,O14949 12 +Mitochondrial envelope 0.4202609799429788 1.1517099655827283 0.2494402757769396 1.0 0.7739482529243401 317 Q8N183,Q96ER9,Q9NS69,Q9Y6N1,Q96AY3,Q8N0X7,Q9NQ50,P00846,Q7Z7H8,Q70HW3,Q567V2,O00264,Q99595,Q9Y619,Q9BUR5,Q7Z7F7,O43772,Q69YU5,Q9NVS2,Q8N4Q1,P09601,P14406,P0DP25,O43169,P82912,P21796,Q9H4A6,Q9BSK2,P45880,Q96NB2,Q9H2D1,Q8IUX1,Q6NUK1,P23786,Q8N4H5,O95563,Q9NR28,O95831,O75964,Q02978,Q96A26,P53701,Q9Y2R0,Q96CU9,Q5T653,O14949,O43676,Q9UDW1,Q6DKK2,Q15070,P30536,Q9UDX5,O60313,O75306,O14925,O95140,O95674,Q9H061,P12235,Q9NPL8,P34897,Q9BUK6,O75880,Q8NI60,P82675,Q9BYT8,Q9NQZ5,Q5XKP0,P20674,Q8N983,Q6P4A7,Q9H3K2,Q86Y39,Q9Y6C9,Q9UBX3,O75438,O95168,Q16134,Q8WWC4,Q9BXK5,Q9Y6M9,Q9UBF8,Q9NX63,Q96TA2,P52789,Q9Y512,Q9BRJ2,Q7KZN9,P82933,O15228 90 +Proton transporting v type atpase complex 0.5426897389789107 1.1449223837083309 0.2522413107671513 1.0 0.7746800934069121 11 Q93050,Q9Y487 2 +Trans golgi network membrane 0.4252455099277251 1.0821566447890243 0.2791829294715926 1.0 0.782931167265286 28 Q7Z6M1,P53365,Q96JB2,O43752,Q9HC07 5 +Intrinsic component of synaptic vesicle membrane 0.5546770169230502 1.0769038750811568 0.2815232117346335 1.0 0.782931167265286 8 Q86Y82,O43752,P61020 3 +Phagocytic cup 0.7301303407405322 1.0766302543314756 0.281645482504965 1.0 0.782931167265286 4 P04083 1 +Integral component of synaptic vesicle membrane 0.7273265739247154 1.0658830432178446 0.2864765151525617 1.0 0.782931167265286 4 Q86Y82,O43752 2 +Mhc protein complex 0.8105832832230833 1.056688171025116 0.2906539253341229 1.0 0.782931167265286 3 P04439,P10321 2 +Mhc class i protein complex 0.8105832832230833 1.056688171025116 0.2906539253341229 1.0 0.782931167265286 3 P04439,P10321 2 +Excitatory synapse 0.6385057196559805 1.0461671674970603 0.2954838586302271 1.0 0.782931167265286 5 Q7L576,Q9UQB8,O15020 3 +Azurophil granule 0.3560333595430088 1.0447563551043006 0.2961355913184214 1.0 0.782931167265286 72 O15400,P07602,P42785,Q92542,P78371,P15291,P08236,P04066,Q07065,P17900,P53634,P61916,Q92820,Q9BRF8,O95721,O43681,Q99829,P51148,Q9NZJ7,Q9H7Z7,P10619,P10253,P06280,Q9BTY2,Q01469,P28482 26 +Chromatoid body 0.8070508889460786 1.043777122949629 0.2965885182840768 1.0 0.782931167265286 3 P06730 1 +Mitotic spindle microtubule 0.546704638189422 1.0386307258833427 0.2989765101877968 1.0 0.782931167265286 8 Q9NVX0,Q96CS2,O94927,Q9H6D7,Q68CZ6 5 +Potassium channel complex 0.8018641010222485 1.0248552043720558 0.3054315138896908 1.0 0.782931167265286 3 P0DP25,Q96ER9 2 +Postsynaptic cytoskeleton 0.772167117523278 1.022550924043964 0.3065202234243922 1.0 0.782931167265286 2 P07196 1 +Cytosolic region 0.5428262324986404 1.0200151722676487 0.3077212651422605 1.0 0.782931167265286 8 Q9UQB8 1 +Cytoplasmic side of endoplasmic reticulum membrane 0.5727414377150247 1.0103666852649278 0.3123196428586383 1.0 0.782931167265286 7 Q8TCT8 1 +Transport vesicle membrane 0.3921557716889829 1.0078133202918311 0.3135440899915176 1.0 0.782931167265286 40 Q86Y82,O15027,P10321,P49755,P04439,P01889,O00429,Q15363,O76024,O75340,P61020,P49257,O43752,P0DP25,Q9Y6Y8 15 +Respiratory chain complex iii 0.539189318152209 1.002563265714058 0.3160716271650243 1.0 0.782931167265286 8 O14949 1 +Palmitoyltransferase complex 0.7661556958220426 0.9986631880808234 0.317957878977724 1.0 0.782931167265286 2 O15270 1 +Endoplasmic reticulum palmitoyltransferase complex 0.7661556958220426 0.9986631880808234 0.317957878977724 1.0 0.782931167265286 2 O15270 1 +Presynaptic active zone 0.4593871410183262 0.9985705560816605 0.3180027694450866 1.0 0.782931167265286 16 P41440 1 +Phagocytic vesicle membrane 0.4199007513657834 0.9966263440101676 0.3189459138290087 1.0 0.782931167265286 25 Q93050,Q9Y487,Q03518 3 +Lumenal side of endoplasmic reticulum membrane 0.5376111390414299 0.9949921106859236 0.3197401014218055 1.0 0.782931167265286 8 P04439,Q8TCT8,P10321 3 +Presynaptic cytosol 0.7077025925701854 0.9909534359887244 0.321708317850373 1.0 0.7856273206804257 4 Q9UQB8 1 +Crd mediated mrna stability complex 0.5957117032691857 0.9715737783247224 0.3312626327543158 1.0 0.7930053697995271 6 O60506 1 +Magnesium dependent protein serine threonine phosphatase complex 0.5128043191989544 0.9698146708715354 0.3321388787176638 1.0 0.7930053697995271 10 P30154 1 +Gamma secretase complex 0.757739705440333 0.965384609023162 0.3343522074782736 1.0 0.7930053697995271 2 Q92542 1 +Bloc complex 0.7520288548241468 0.9429208702660165 0.3457213789618671 1.0 0.7930053697995271 2 Q86YV9 1 +Cytochrome complex 0.4366197901725511 0.9414276518220608 0.34648574865737 1.0 0.7930053697995271 18 O14949,P14406,P20674,Q9UDW1 4 +Brush border membrane 0.5106555790317235 0.9393236045133764 0.3475646230242537 1.0 0.7930053697995271 9 P15291,P41440 2 +Clathrin coated vesicle 0.3651893490092974 0.9201300956732372 0.3575047788626966 1.0 0.800942722278087 53 Q9BVK6,O14641,Q99523,Q5VW38,P42892,Q9P253,O43752,Q14108 8 +Mib complex 0.4967203171324355 0.8883056185176744 0.3743763782532463 1.0 0.8129062310007598 10 Q9BUR5,Q5XKP0,Q9Y512,Q9NX63 4 +Endoplasmic reticulum tubular network 0.4757536243302924 0.86356805413334 0.3878252195840725 1.0 0.8129062310007598 12 Q6NUK4,Q9H6H4,P50402 3 +Prefoldin complex 0.5688890101447857 0.8590686166793344 0.390302660579835 1.0 0.8129062310007598 6 Q9UHV9,O60925 2 +Cd40 receptor complex 0.7429980095321325 0.8141384812136035 0.4155656231392086 1.0 0.8361070496265974 3 Q9NR28 1 +Mitochondrial large ribosomal subunit 0.3870394268244014 0.8130178678417492 0.4162078138869707 1.0 0.8361070496265974 30 Q5T653,Q7Z7F7,Q8N983,Q9NVS2,Q9NQ50,Q7Z7H8,Q567V2,Q9BRJ2 8 +Chromaffin granule membrane 0.7168620378719599 0.8071257067933734 0.4195940629285002 1.0 0.8373396938617207 2 P20073 1 +Histone pre mrna 3 end processing complex 0.7362222904381788 0.7905025914975696 0.4292343093683273 1.0 0.8418954041300597 3 O60506 1 +Eukaryotic translation initiation factor 2b complex 0.549974604293918 0.7805894776069374 0.4350439824976619 1.0 0.8431042999718067 6 Q13144,Q9NR50,P49770 3 +Mcrd mediated mrna stability complex 0.5723993430924661 0.7780023279094308 0.4365676408480978 1.0 0.8433481505509097 5 Q14103,O60506 2 +Membrane microdomain 0.3383158487560218 0.7668304494481912 0.4431823298344102 1.0 0.8543046613403737 67 P50897,Q86Y82,P21796,P78536,P30154,P46108,P28482,Q8WTV0,O15118,Q9Y2Q5,P09601,P41440,P49327,P35613 14 +Rnai effector complex 0.5158110148892081 0.7565561297749814 0.449315832679912 1.0 0.8570108303326323 7 P06730 1 +Ficolin 1 rich granule membrane 0.4068985825481072 0.7507563003563578 0.4527993332639681 1.0 0.8582347195337974 18 P42785 1 +Golgi apparatus 0.389969555413003 0.7436634796723725 0.457080088764598 1.0 0.8645397921100747 326 P50897,Q16739,P62993,Q92614,O95197,Q99523,Q9BXS4,Q15392,Q8IV08,O43852,Q8NCH0,P53365,O43731,Q9UJX6,Q96S66,Q7RTS9,P24390,Q14108,O43823,Q8IZA0,Q93050,P18085,P10321,Q9NPR9,P42858,O43505,P80303,Q4J6C6,O75503,O43909,Q8IUR0,O43752,O95721,Q8NBN3,P04062,Q9BVK6,Q9UQB8,Q02818,Q7Z6M1,Q5VW38,P49257,P49327,Q9HC07,P84085,P35613,Q9Y282,Q9P260,O15027,Q9P2W9,Q16799,P20645,O00461,O95456,Q15363,Q96JB2,P28482,O60476,Q99805 58 +Cytoplasmic side of membrane 0.3478236264177911 0.7380176387967927 0.4605037305255588 1.0 0.8684122717634107 47 P62942,Q9NR28,Q8TCT8 3 +Protein lipid complex 0.5609059154899935 0.7325259604679538 0.4638476033909098 1.0 0.8700743864848123 5 Q9BUR5,Q9UHG3 2 +Chromaffin granule 0.7170775706554368 0.7246261977357258 0.4686813825725413 1.0 0.8754729857692034 3 P20073,P10909 2 +Vacuolar membrane 0.365908431673314 0.7120117822360852 0.4764574800271168 1.0 0.8757821403143176 132 Q99523,Q9BXS4,Q9UIQ6,Q8WTV0,Q8IV08,Q9NQ11,P42785,P07602,Q9Y487,Q9P253,Q14108,Q07065,Q86YV9,Q93050,O75503,P41440,O95721,P04062,Q8TCT8,P42892,P10619,Q9HC07 22 +Presynapse 0.3416224703449926 0.7113486608092772 0.4768682044108685 1.0 0.8757821403143176 96 P50897,Q86Y82,O15400,O14936,Q9P253,Q96A57,Q06787,P51790,P42858,Q9BT78,P07196,P41440,O43752,P0DP25,O95721,P51114,Q9BVK6,Q9UQB8,Q92905,Q7L576,Q9Y639,Q07021,P51116,Q96CX2,P35080,O76024,Q00535,P61020,O15020,O00429 30 +Proteasome core complex alpha subunit complex 0.5048896297438696 0.7087329033403902 0.4784902422247099 1.0 0.8757821403143176 7 P25786 1 +Exocytic vesicle 0.357473291419441 0.7070429682817657 0.4795397759816064 1.0 0.875933542418015 40 P50897,Q86Y82,P51790,Q9BVK6,O15400,O43752,Q9BT78,O76024,Q92905,P61020,O00429,Q96A57,Q92542,P0DP25 14 +Cation channel complex 0.4324531062230932 0.6957947711109643 0.4865573643249992 1.0 0.8792752384181395 13 P62942 1 +Snare complex 0.4076974523675652 0.6835365959759259 0.4942678336594603 1.0 0.8792752384181395 16 O43752,O95721,Q9P2W9 3 +Cornified envelope 0.5252985824236631 0.6798049168201028 0.4966279930021862 1.0 0.8792752384181395 6 P04083,P04080 2 +Ciliary transition zone 0.4967200019816187 0.67324397099363 0.5007920914225776 1.0 0.8792752384181395 7 A6NIH7 1 +Hrd1p ubiquitin ligase erad l complex 0.6975700255666216 0.6590799706519541 0.5098444167816774 1.0 0.881524888557633 3 Q9BUN8 1 +Er ubiquitin ligase complex 0.6975700255666216 0.6590799706519541 0.5098444167816774 1.0 0.881524888557633 3 Q9BUN8 1 +Perinuclear endoplasmic reticulum 0.5181441735678307 0.6510182523342626 0.5150347046245232 1.0 0.8838113144240346 6 P10909,Q9H4L5 2 +Hulc complex 0.6720769461977787 0.6426239918134596 0.5204681115233869 1.0 0.8863611072183994 2 Q5VTR2 1 +Cell body membrane 0.6705740907724651 0.6373112902385234 0.5239220982583945 1.0 0.887240039293655 2 P55011 1 +Microbody lumen 0.3788342680243038 0.6205930154695338 0.5348674363631436 1.0 0.8913676162581311 20 O75874,Q15067 2 +Beta catenin destruction complex 0.4821342708923313 0.6106055223983496 0.5414607658461668 1.0 0.8940712246466717 7 Q9UJX6,P25054,Q9HB71 3 +Ion channel complex 0.3847650520426381 0.6103281889410631 0.5416444273395717 1.0 0.8940712246466717 18 P62942 1 +P body 0.33861114714044 0.6101361279988625 0.5417716361269567 1.0 0.8940712246466717 44 Q7Z739,P19474,Q9NRW3,P60900,Q5T6F2,P62312,P06730,Q9Y5A9 8 +Early endosome 0.3399170481647596 0.5969074246728827 0.5505691899445992 1.0 0.8971505145500124 107 Q86Y82,Q99523,Q9UIQ6,Q8IV08,Q5SW96,Q9P253,P11717,Q9UMY4,Q86YV9,Q96L92,P10321,P42858,Q92783,Q9Y5X3,P41440,O43752,Q13510,Q9HD42,P51148,Q9BUN8,O95630,Q5VW38,Q9Y2I1,Q9HC07,P02786,P30048,P04083,P61020,P04439,P01889,P28482 31 +U2af complex 0.6762487997098949 0.5895921921044911 0.5554640875724008 1.0 0.9002691651889001 3 Q01081 1 +Eukaryotic translation initiation factor 4f complex 0.4471131479830457 0.5689488324548898 0.5693908645359571 1.0 0.919551021870904 8 Q15056,P06730 2 +Gid complex 0.6414186955214833 0.5374895961746565 0.5909294694682248 1.0 0.9376218902595652 2 Q9H871 1 +Endoplasmic reticulum exit site 0.3779074894252483 0.5350145799207168 0.5926397754270427 1.0 0.9384203362160014 17 O75340,O15027,Q96PC5,Q92734 4 +Neuron spine 0.3465908314978106 0.5272369227954886 0.5980290711251124 1.0 0.9391194331429188 33 P51116,Q9UQB8,P18085,Q14168,P51114 5 +Transporter complex 0.3214988923764978 0.5215273269969375 0.6019994740775776 1.0 0.9391194331429188 60 P62942,O43676,Q96CU9,Q9UDW1,O75306,O75438,Q86Y39,Q96S66,Q8N2K0,O14949 10 +Pole plasm 0.50413872564847 0.5169319531684389 0.6052036611130029 1.0 0.942121163175912 5 Q9HCE1,Q9Y2W6 2 +Ubiquitin conjugating enzyme complex 0.5701118552107387 0.4979654572342707 0.6185083893006158 1.0 0.94977728933281 4 Q5VTR2,P61088 2 +Contractile fiber 0.3161573726123784 0.4668900228261626 0.6405785638678152 1.0 0.9630630163997064 60 P62942,P60900,P09493,P49257,O75880 5 +Lipid droplet 0.3407061944808132 0.4601886286331248 0.6453808324052608 1.0 0.9664711308415972 30 P48449,Q07065,Q99720,Q01105 4 +Pigment granule 0.3146583197980283 0.4576510857511523 0.6472031351786502 1.0 0.9670313727678784 61 P55209,Q93050,P02786,P49327,Q92820,O43852,P07858,P61020,P41440,P57088,P35613 11 +Nucleoid 0.3352239953408217 0.4566958523234102 0.6478896724835566 1.0 0.9670313727678784 35 P21796,P45880,Q04837,P34897,Q9NYY8,P51530 6 +Intrinsic component of mitochondrial outer membrane 0.3759925460064224 0.4479809527422029 0.654166943104298 1.0 0.9697893490721085 14 Q9UH62,P57105,O95140 3 +Tertiary granule lumen 0.3693961909615364 0.4330242062862062 0.6649971843858558 1.0 0.9705946078422184 15 P04080,Q92820,O75874,Q13510,P09960 5 +Bcl 2 family protein complex 0.6083558761647112 0.4329541800099243 0.665048057744136 1.0 0.9705946078422184 2 Q07812 1 +Early endosome membrane 0.3136038294053476 0.4148132121089487 0.6782786468551318 1.0 0.973883445405308 51 Q86Y82,Q86YV9,Q96L92,P51790,Q92783,P10321,P51148,Q8IV08,Q9Y5X3,P04083,P61020,P04439,P01889,Q9HC07,Q9UMY4 15 +Neuron projection membrane 0.4103174165172786 0.4068907672383212 0.6840882173841409 1.0 0.9745030266509932 8 Q14168 1 +Organellar ribosome 0.3109566476774502 0.3950816918271446 0.692782599918619 1.0 0.9808640795785826 46 P82933,Q9BRJ2,Q5T653,Q7Z7F7,P82675,Q8N983,Q9NVS2,Q9NQ50,Q7Z7H8,Q567V2,P82912 11 +Filopodium tip 0.4688247438366371 0.3937552192287765 0.6937617688108408 1.0 0.9808640795785826 5 Q9H4L5,Q06787 2 +Nadh dehydrogenase complex 0.3304511959416945 0.3734515148588186 0.7088124247975855 1.0 0.9889521409734024 26 O43676,Q96CU9,O75306,O75438,O95168,Q86Y39 6 +Basal part of cell 0.308960561012912 0.3729923815526708 0.7091541141246143 1.0 0.9889521409734024 48 P53985,P02786,P42785,P04083,Q14168,P41440,P15291,P35613 8 +Respiratory chain complex iv 0.3879862719966483 0.3690941534338018 0.7120575466589409 1.0 0.9889521409734024 11 P14406 1 +Nuclear ubiquitin ligase complex 0.3796089086697961 0.3680184870220709 0.7128594494492944 1.0 0.9889521409734024 12 Q96DE5,O60566,Q9UJX6,Q9UJX3,Q16763 5 +Tim22 mitochondrial import inner membrane insertion complex 0.5852119026149757 0.3662766817838424 0.7141586276772607 1.0 0.9889521409734024 2 Q53H12 1 +Endocytic vesicle 0.3079641656229568 0.3651882097603958 0.7149709186948991 1.0 0.9889521409734024 91 Q86Y82,Q5KU26,Q8WTV0,Q5SW96,Q9Y487,P11717,Q14108,Q93050,P10321,Q969Q5,O43752,P51148,P11233,O14641,P02786,Q03518,O00461,P20645,P61020,P04439,P01889,P08670 22 +Lateral plasma membrane 0.3370685993735115 0.3605758777222692 0.7184165246499072 1.0 0.9899056301421112 21 P53985,O14641,P25054,P05023,P04083,P30153,Q9ULV4,Q5T2T1,P36404,P55011 10 +Cuticular plate 0.5792004809137397 0.3499290423305216 0.7263919506710117 1.0 0.992192158337186 2 Q9Y5X1 1 +Mitochondrial protein containing complex 0.3493092710766625 0.3489237482770393 0.7271465557783252 1.0 0.992192158337186 158 P12235,Q96CU9,Q9NS69,O75438,O95168,Q9NQ50,P00846,Q5T653,Q7Z7H8,Q567V2,O14949,Q99595,O43676,Q9BUR5,Q7Z7F7,Q9UDW1,Q9NVS2,P14406,P21796,P82675,Q9Y6M9,Q9NX63,Q8N4H5,Q9Y512,Q9BRJ2,Q5XKP0,P82933,P20674,O75964,Q8N983,O75306,O14925,Q86Y39 33 +Intrinsic component of vacuolar membrane 0.5932254834346593 0.3479906845287671 0.7278471794684815 1.0 0.992192158337186 3 Q9NQ11 1 +Neuromuscular junction 0.3490609661156081 0.3418501966112571 0.7324636313195698 1.0 0.992192158337186 16 Q14168,P07196,Q00535,P11047 4 +Dynactin complex 0.4500730244374601 0.3330405513805696 0.7391036731406659 1.0 0.992192158337186 5 Q13561,Q9UJW0,P61163 3 +Death inducing signaling complex 0.5150389445541551 0.3324150029100787 0.7395759113616367 1.0 0.992192158337186 4 P49327,P42574 2 +Mitochondrial intermembrane space protein transporter complex 0.585387853277199 0.328149659886454 0.7427985077552739 1.0 0.992192158337186 3 Q9Y5J9,O60220 2 +Immunological synapse 0.3602794122070579 0.3160295414998817 0.7519800854739653 1.0 0.997444877411241 13 Q9Y639 1 +Trans golgi network transport vesicle 0.3599377467852998 0.3143551751731723 0.7532512967569538 1.0 0.997444877411241 13 Q99523 1 +Dendritic spine membrane 0.5650736399158446 0.3131867465765326 0.7541387870051877 1.0 0.997444877411241 2 P20020 1 +Chloride channel complex 0.4407246240604703 0.3041911901550386 0.760982236262018 1.0 1.0 5 Q96S66 1 +Phagophore assembly site membrane 0.4356197352587063 0.2888657468316473 0.7726841168730221 1.0 1.0 5 Q9H0U4,Q5MNZ6,Q7Z3C6,Q9Y4P8 4 +Photoreceptor outer segment 0.3991342880272499 0.2827842418353611 0.7773422346972179 1.0 1.0 7 P35613 1 +Neuron projection terminus 0.3381905157786706 0.2826534441769961 0.7774425075713505 1.0 1.0 16 Q7L576,Q06787,Q9UQB8 3 +Filopodium 0.3147253703964264 0.2776935861011821 0.7812475845806945 1.0 1.0 32 Q13576,P51116,Q9UQB8,P15291,Q9H4L5,Q00535,Q06787,P51114 8 +Blood microparticle 0.322306694221825 0.2595788814535637 0.7951886282104899 1.0 1.0 19 P02786,P38435,P17066,P10909,P04062 5 +Core mediator complex 0.3885161497990572 0.2459748390187358 0.805701709772213 1.0 1.0 7 O60244,Q13503 2 +Hops complex 0.5398047945013772 0.2251368687144811 0.8218728000388844 1.0 1.0 3 Q9P253 1 +Phagophore assembly site 0.3608328281082463 0.2109185143791768 0.832950856718965 1.0 1.0 8 Q86Y82,Q7Z3C6 2 +Endoplasmic reticulum tubular network membrane 0.526458208057705 0.1992386519995436 0.8420760655465069 1.0 1.0 3 Q8NHH9,Q9NQC3 2 +Meiotic spindle 0.5112714156898157 0.1964023798181397 0.8442952337105645 1.0 1.0 2 Q9NQS7 1 +Azurophil granule lumen 0.2899660461578779 0.1923621335863932 0.8474585514697668 1.0 1.0 45 P04066,P17900,P53634,P61916,P28482,Q92820,Q9BTY2,Q9BRF8,Q9H7Z7,O43681,Q01469,P10619,P06280,P78371,P08236 15 +Ciliary membrane 0.3905270206948504 0.168153629117519 0.8664624200145739 1.0 1.0 5 O95721 1 +Tertiary granule 0.2909240129116384 0.1653654797155758 0.8686563227678279 1.0 1.0 42 Q93050,P04080,Q92820,O75874,P42785,Q13510,P09960 7 +Euchromatin 0.2988545807064208 0.1540486029737322 0.8775714132985168 1.0 1.0 25 Q9GZS3,Q7KZ85,Q8IZL8,P38159,Q6PGP7 5 +Pericentriolar material 0.4764051698226623 0.1412266986630485 0.8876908549676021 1.0 1.0 2 Q15154 1 +Photoreceptor inner segment 0.3545924654472462 0.139335629260423 0.8891849363967648 1.0 1.0 7 P35613 1 +Rpap3 r2tp prefoldin like complex 0.3384309308531313 0.1339780160449114 0.8934199583438338 1.0 1.0 8 Q9UBK9,P19388 2 +Neuron to neuron synapse 0.2805221350145013 0.1331725111924433 0.8940569500733808 1.0 1.0 65 Q99720,P51991,P51116,Q9UQB8,P55795,Q14168,Q01469,P51114,Q9Y639 9 +Basal dendrite 0.4691914637811856 0.1317968746376065 0.8951449586658851 1.0 1.0 2 O15498 1 +Phagocytic vesicle 0.2828284234778124 0.1316121599617112 0.8952910669396639 1.0 1.0 45 Q86Y82,P51790,Q93050,P10321,Q03518,P08670,Q9Y487,P04439,P01889,O43752 10 +Vacuole 0.3560556229386109 0.1298241398982452 0.8967055636653387 1.0 1.0 235 P50897,Q99523,Q9BXS4,Q8NHP8,Q9UIQ6,Q8WTV0,Q8IV08,Q9NQ11,P42785,Q5BJF2,P07602,O15118,Q9Y487,Q9P253,Q14108,Q07065,Q86YV9,Q93050,P17900,P42858,Q92820,Q9BRF8,Q9UMR5,O75503,P41440,O95721,Q13510,P04062,Q8N511,P19474,Q8TCT8,P42892,P07858,Q8NCC3,P10619,Q9HC07,Q15165,P38435,Q9UM22,Q9BTY2,P20645,Q9UHG3,Q01469,P28482 44 +Hippocampal mossy fiber to ca3 synapse 0.4711365003006607 0.113539011474495 0.9096032363438464 1.0 1.0 3 P47756,O60716 2 +Myosin ii complex 0.4135338345864697 0.1134772285702638 0.909652215425218 1.0 1.0 4 Q7Z406,P60660,P35579 3 +Tubular endosome 0.4074220893172305 0.1044540352002066 0.9168090432697812 1.0 1.0 4 Q9Y5X3 1 +Gemini of coiled bodies 0.3523680340875357 0.1029159052759909 0.9180297141469324 1.0 1.0 6 Q9NWZ8,P57678 2 +High density lipoprotein particle 0.4593064846869809 0.0996816399220532 0.9205970771528658 1.0 1.0 3 Q9BUR5 1 +Oxidoreductase complex 0.2787154538080174 0.0935767010492369 0.925445418254323 1.0 1.0 59 O43676,P13674,Q96CU9,Q9UDW1,O75306,O75438,O95168,Q86Y39,O43169,O14949 10 +Annulate lamellae 0.3504813477737745 0.0857424449977856 0.9316711601198197 1.0 1.0 5 Q8TD16,O14980,P63241,Q9Y5L0 4 +Tho complex 0.348977135980748 0.0831304992992598 0.9337477748373286 1.0 1.0 5 Q13769,Q8NI27,Q96FV9,Q86W42 4 +Mediator complex 0.3146736148760995 0.0719479335292816 0.9426433434233964 1.0 1.0 11 O60244,P11802,Q13503 3 +Myosin filament 0.4134095009019855 0.0594584972902479 0.9525869213262406 1.0 1.0 3 Q7Z406,P35579 2 +Cullin ring ubiquitin ligase complex 0.2830385011198361 0.0569408547553966 0.9545923097000028 1.0 1.0 32 Q5TAQ9,Q9HB71,Q96DE5,O60566,Q9UJX6,Q96K76,Q9UJX3,Q16763,O75340 9 +Outer kinetochore 0.3123042344371884 0.0559607048707528 0.9553731110512318 1.0 1.0 8 Q96EA4,O60566 2 +Cop9 signalosome 0.3094678386050484 0.0553593161915051 0.955852207082593 1.0 1.0 10 P62993,Q92905 2 +Alpha dna polymerase primase complex 0.3313771193515772 0.0551764636020479 0.9559978796890636 1.0 1.0 5 Q14181 1 +Ribonuclease mrp complex 0.4045709055675639 0.0539359079816362 0.95698622785855 1.0 1.0 3 Q99575 1 +Extrinsic component of membrane 0.2716650873388168 0.0503656166050157 0.9598310355705184 1.0 1.0 66 P62942,Q8NI60,P31749,P04083,Q9UJX6,Q06787,P04062 7 +Clathrin coated endocytic vesicle membrane 0.2905159431912455 0.0502663129569186 0.9599101681848334 1.0 1.0 16 Q5SW96,Q14108,P20645,P02786 4 +Dna polymerase complex 0.299338857805255 0.0500215796823515 0.9601051917463316 1.0 1.0 13 Q9Y2S7,Q9NR33,Q14181 3 +Axon initial segment 0.322212203186052 0.0499230877187663 0.960183678901798 1.0 1.0 2 Q12955 1 +Basolateral plasma membrane 0.2787209080946853 0.0481127528683195 0.96162638265761 1.0 1.0 39 P53985,P02786,P04083,Q14168,P41440,P15291,P35613 7 +Smn complex 0.3243126306800153 0.0461274703661634 0.963208651120746 1.0 1.0 6 Q9NWZ8,P57678 2 +Sperm annulus 0.38394467829223 0.0434119906866256 0.9653731195274348 1.0 1.0 3 Q16181,Q14141 2 +Brca1 a complex 0.3806374022850307 0.0420056226771833 0.9664942158268108 1.0 1.0 3 P38398,Q9NXR7 2 +Neurofibrillary tangle 0.3272013417703426 0.0275941276329632 0.9779858653536124 1.0 1.0 3 P10909 1 +Sodium potassium exchanging atpase complex 0.3162958508719237 0.0261043846911791 0.9791740797778694 1.0 1.0 3 P05026,P05023 2 +Atpase dependent transmembrane transport complex 0.3162958508719237 0.0261043846911791 0.9791740797778694 1.0 1.0 3 P05026,P05023 2 +Cation transporting atpase complex 0.3162958508719237 0.0261043846911791 0.9791740797778694 1.0 1.0 3 P05026,P05023 2 +Specific granule 0.2763931538573395 0.0229370064206172 0.9817005212984152 1.0 1.0 37 Q07065,P30519,Q92820,Q14165,Q9Y2Q5,Q7L576,O00264 7 +Spectrin 0.3046616541353425 0.0170396351014369 0.9864049961170352 1.0 1.0 4 Q01082,Q13813,O15020 3 +Nuclear envelope lumen 0.297265599664145 0.0144797503989399 0.988447234412063 1.0 1.0 4 Q9HB71 1 +Gap junction 0.2845112781954932 0.0108497725038602 0.9913433038721422 1.0 1.0 4 Q16643,Q69YQ0,Q99797 3 +Presynaptic membrane 0.2743996137453573 0.0090284855543629 0.9927964086339276 1.0 1.0 19 O14936,Q06787,Q96CX2,Q9Y639 4 +Spindle midzone 0.2734869318089021 0.004894154959622 0.9960950449086176 1.0 1.0 19 Q53HL2,P53350,Q02224,Q15555 4 +Epsilon dna polymerase complex 0.2814792620855033 0.000622143449642 0.9995036013789488 1.0 1.0 5 Q9NRF9,Q9NR33 2 diff --git a/msigdb_gocc/selections.json b/msigdb_gocc/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..4ad08992a48085b7dad8a4bf2edda4ffe4419c21 --- /dev/null +++ b/msigdb_gocc/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["90s preribosome", "9plus0 non motile cilium", "9plus2 motile cilium", "A band", "Acrosomal membrane", "Acrosomal vesicle", "Actin based cell projection", "Actin cytoskeleton", "Actin filament", "Actin filament bundle", "Actomyosin", "Adherens junction", "Aggresome", "Alpha dna polymerase primase complex", "Alveolar lamellar body", "Aminoacyl trna synthetase multienzyme complex", "Ampa glutamate receptor complex", "Amphisome", "Amphisome membrane", "Anaphase promoting complex", "Anchored component of membrane", "Anchored component of plasma membrane", "Anchored component of postsynaptic membrane", "Anchored component of synaptic membrane", "Anchored component of synaptic vesicle membrane", "Anchoring junction", "Annulate lamellae", "Ap 1 adaptor complex", "Ap 3 adaptor complex", "Ap type membrane coat adaptor complex", "Apical dendrite", "Apical junction complex", "Apical part of cell", "Apical plasma membrane", "Apicolateral plasma membrane", "Arp2 3 protein complex", "Aryl hydrocarbon receptor complex", "Aster", "Astrocyte end foot", "Astrocyte projection", "Atac complex", "Atpase complex", "Atpase dependent transmembrane transport complex", "Autolysosome", "Autophagosome", "Autophagosome membrane", "Axolemma", "Axon", "Axon cytoplasm", "Axon hillock", "Axon initial segment", "Axonal growth cone", "Axonemal microtubule", "Azurophil granule", "Azurophil granule lumen", "Azurophil granule membrane", "B wich complex", "Barr body", "Basal cortex", "Basal dendrite", "Basal part of cell", "Basement membrane", "Basolateral plasma membrane", "Bcl 2 family protein complex", "Beta catenin destruction complex", "Beta catenin tcf complex", "Bleb", "Bloc 1 complex", "Bloc complex", "Blood microparticle", "Borc complex", "Box c d rnp complex", "Box h aca rnp complex", "Box h aca snornp complex", "Box h aca telomerase rnp complex", "Brca1 a complex", "Brca1 c complex", "Brisc complex", "Brush border", "Brush border membrane", "Cajal body", "Calcineurin complex", "Calcium and calmodulin dependent protein kinase complex", "Calcium channel complex", "Camp dependent protein kinase complex", "Carboxy terminal domain protein kinase complex", "Caspase complex", "Catalytic complex", "Catalytic step 1 spliceosome", "Catalytic step 2 spliceosome", "Catenin complex", "Cation channel complex", "Cation transporting atpase complex", "Catsper complex", "Caveola", "Ccaat binding factor complex", "Ccr4 not complex", "Ccr4 not core complex", "Cd40 receptor complex", "Cd95 death inducing signaling complex", "Cdc73 paf1 complex", "Cell body", "Cell body fiber", "Cell body membrane", "Cell cell contact zone", "Cell cell junction", "Cell cortex", "Cell cortex region", "Cell division site", "Cell leading edge", "Cell pole", "Cell projection membrane", "Cell substrate junction", "Cell surface", "Cell tip", "Cell trailing edge", "Central element", "Centriolar satellite", "Centriolar subdistal appendage", "Centriole", "Centrosome", "Cerebellar mossy fiber", "Chaperone complex", "Chaperonin containing t complex", "Checkpoint clamp complex", "Chitosome", "Chloride channel complex", "Cholinergic synapse", "Chromaffin granule", "Chromaffin granule membrane", "Chromatin", "Chromatin silencing complex", "Chromatoid body", "Chromocenter", "Chromosomal region", "Chromosome", "Chromosome centromeric core domain", "Chromosome centromeric region", "Chromosome passenger complex", "Chromosome telomeric region", "Chromosome telomeric repeat region", "Cia complex", "Ciliary basal body", "Ciliary base", "Ciliary membrane", "Ciliary plasm", "Ciliary rootlet", "Ciliary tip", "Ciliary transition zone", "Cilium", "Cis golgi network", "Cis golgi network membrane", "Clathrin adaptor complex", "Clathrin coat", "Clathrin coat of coated pit", "Clathrin coat of endocytic vesicle", "Clathrin coated endocytic vesicle", "Clathrin coated endocytic vesicle membrane", "Clathrin coated pit", "Clathrin coated vesicle", "Clathrin coated vesicle membrane", "Clathrin complex", "Clathrin sculpted gamma aminobutyric acid transport vesicle", "Clathrin sculpted vesicle", "Clathrin vesicle coat", "Cleavage furrow", "Cluster of actin based cell projections", "Coated vesicle", "Coated vesicle membrane", "Cohesin complex", "Collagen containing extracellular matrix", "Collagen trimer", "Commitment complex", "Compact myelin", "Condensed chromosome", "Condensed chromosome centromeric region", "Condensed nuclear chromosome", "Condensin complex", "Contractile fiber", "Contractile ring", "Cop9 signalosome", "Copi coated vesicle", "Copi coated vesicle membrane", "Copi vesicle coat", "Copii coated er to golgi transport vesicle", "Copii vesicle coat", "Core mediator complex", "Cornified envelope", "Cortical actin cytoskeleton", "Cortical cytoskeleton", "Cortical endoplasmic reticulum", "Cortical granule", "Costamere", "Crd mediated mrna stability complex", "Ctf18 rfc like complex", "Cul2 ring ubiquitin ligase complex", "Cul3 ring ubiquitin ligase complex", "Cul4 ring e3 ubiquitin ligase complex", "Cul4a ring e3 ubiquitin ligase complex", "Cul4b ring e3 ubiquitin ligase complex", "Cul5 ring ubiquitin ligase complex", "Cullin ring ubiquitin ligase complex", "Cuticular plate", "Cyclin a2 cdk2 complex", "Cyclin dependent protein kinase holoenzyme complex", "Cytochrome complex", "Cytolytic granule", "Cytoplasmic dynein complex", "Cytoplasmic exosome rnase complex", "Cytoplasmic microtubule", "Cytoplasmic region", "Cytoplasmic side of endoplasmic reticulum membrane", "Cytoplasmic side of endosome membrane", "Cytoplasmic side of lysosomal membrane", "Cytoplasmic side of membrane", "Cytoplasmic stress granule", "Cytoplasmic ubiquitin ligase complex", "Cytoskeleton of presynaptic active zone", "Cytosolic large ribosomal subunit", "Cytosolic region", "Cytosolic ribosome", "Cytosolic small ribosomal subunit", "Death inducing signaling complex", "Dendrite cytoplasm", "Dendrite membrane", "Dendrite terminus", "Dendritic growth cone", "Dendritic shaft", "Dendritic spine membrane", "Dendritic tree", "Dense body", "Dense core granule", "Dentate gyrus mossy fiber", "Derlin 1 retrotranslocation complex", "Desmosome", "Deuterosome", "Dihydrolipoyl dehydrogenase complex", "Distal axon", "Dna packaging complex", "Dna polymerase complex", "Dna repair complex", "Dna replication factor c complex", "Dna replication preinitiation complex", "Dopaminergic synapse", "Dynactin complex", "Dynein axonemal particle", "Dynein complex", "Dystrophin associated glycoprotein complex", "Early endosome", "Early endosome lumen", "Early endosome membrane", "Early phagosome", "Ekc keops complex", "Elongator holoenzyme complex", "Elongin complex", "Emc complex", "Endocytic vesicle", "Endocytic vesicle lumen", "Endocytic vesicle membrane", "Endolysosome", "Endolysosome lumen", "Endolysosome membrane", "Endopeptidase complex", "Endoplasmic reticulum", "Endoplasmic reticulum chaperone complex", "Endoplasmic reticulum exit site", "Endoplasmic reticulum golgi intermediate compartment", "Endoplasmic reticulum golgi intermediate compartment membrane", "Endoplasmic reticulum lumen", "Endoplasmic reticulum palmitoyltransferase complex", "Endoplasmic reticulum plasma membrane contact site", "Endoplasmic reticulum protein containing complex", "Endoplasmic reticulum quality control compartment", "Endoplasmic reticulum tubular network", "Endoplasmic reticulum tubular network membrane", "Endoribonuclease complex", "Endosome", "Endosome lumen", "Endosome membrane", "Envelope", "Enzyme activator complex", "Epsilon dna polymerase complex", "Equatorial microtubule organizing center", "Er membrane insertion complex", "Er to golgi transport vesicle membrane", "Er ubiquitin ligase complex", "Esc e z complex", "Escrt complex", "Escrt i complex", "Escrt iii complex", "Euchromatin", "Eukaryotic translation initiation factor 2 complex", "Eukaryotic translation initiation factor 2b complex", "Eukaryotic translation initiation factor 3 complex", "Eukaryotic translation initiation factor 3 complex eif3m", "Eukaryotic translation initiation factor 4f complex", "Excitatory synapse", "Exocyst", "Exocytic vesicle", "Exon exon junction complex", "Exoribonuclease complex", "External encapsulating structure", "External side of apical plasma membrane", "External side of plasma membrane", "Extrinsic component of cytoplasmic side of plasma membrane", "Extrinsic component of endoplasmic reticulum membrane", "Extrinsic component of endosome membrane", "Extrinsic component of external side of plasma membrane", "Extrinsic component of membrane", "Extrinsic component of mitochondrial inner membrane", "Extrinsic component of organelle membrane", "Extrinsic component of plasma membrane", "Extrinsic component of postsynaptic membrane", "Extrinsic component of postsynaptic specialization membrane", "Extrinsic component of synaptic membrane", "F actin capping protein complex", "Fanconi anaemia nuclear complex", "Fascia adherens", "Female germ cell nucleus", "Female pronucleus", "Fhf complex", "Fibrillar center", "Ficolin 1 rich granule", "Ficolin 1 rich granule lumen", "Ficolin 1 rich granule membrane", "Filamentous actin", "Filopodium", "Filopodium membrane", "Filopodium tip", "Filtration diaphragm", "Flemming body", "Flotillin complex", "Gaba ergic synapse", "Gamma secretase complex", "Gamma tubulin complex", "Gamma tubulin large complex", "Gap junction", "Gator2 complex", "Gemini of coiled bodies", "Germ cell nucleus", "Gid complex", "Glial cell projection", "Glutamatergic synapse", "Glycinergic synapse", "Glycogen granule", "Glycoprotein complex", "Golgi apparatus", "Golgi apparatus subcompartment", "Golgi associated vesicle", "Golgi associated vesicle membrane", "Golgi cis cisterna", "Golgi cisterna", "Golgi cisterna membrane", "Golgi lumen", "Golgi medial cisterna", "Golgi membrane", "Golgi stack", "Golgi trans cisterna", "Golgi transport complex", "Gpi anchor transamidase complex", "Granular component", "Growth cone membrane", "Gtpase complex", "Guanyl nucleotide exchange factor complex", "H3 histone acetyltransferase complex", "H4 h2a histone acetyltransferase complex", "H4 histone acetyltransferase complex", "Haus complex", "Hemidesmosome", "Hemoglobin complex", "Heterochromatin", "Hfe transferrin receptor complex", "High density lipoprotein particle", "Hippocampal mossy fiber", "Hippocampal mossy fiber to ca3 synapse", "Histone deacetylase complex", "Histone methyltransferase complex", "Histone pre mrna 3 end processing complex", "Hops complex", "Host cellular component", "Hrd1p ubiquitin ligase erad l complex", "Hulc complex", "I band", "Ikappab kinase complex", "Immunological synapse", "Inclusion body", "Inflammasome complex", "Inhibitory synapse", "Inner mitochondrial membrane protein complex", "Ino80 complex", "Ino80 type complex", "Insulin responsive compartment", "Integral component of cytoplasmic side of endoplasmic reticulum membrane", "Integral component of lysosomal membrane", "Integral component of presynaptic active zone membrane", "Integral component of synaptic vesicle membrane", "Integrator complex", "Integrin complex", "Intercalated disc", "Intercellular bridge", "Intercellular canaliculus", "Intermediate filament", "Intermediate filament cytoskeleton", "Intracellular protein containing complex", "Intraciliary transport particle", "Intraciliary transport particle b", "Intrinsic component of endoplasmic reticulum membrane", "Intrinsic component of golgi membrane", "Intrinsic component of mitochondrial inner membrane", "Intrinsic component of mitochondrial membrane", "Intrinsic component of mitochondrial outer membrane", "Intrinsic component of nuclear inner membrane", "Intrinsic component of organelle membrane", "Intrinsic component of peroxisomal membrane", "Intrinsic component of plasma membrane", "Intrinsic component of postsynaptic density membrane", "Intrinsic component of postsynaptic membrane", "Intrinsic component of postsynaptic specialization membrane", "Intrinsic component of presynaptic active zone membrane", "Intrinsic component of presynaptic membrane", "Intrinsic component of synaptic membrane", "Intrinsic component of synaptic vesicle membrane", "Intrinsic component of the cytoplasmic side of the plasma membrane", "Intrinsic component of vacuolar membrane", "Ion channel complex", "Iron sulfur cluster assembly complex", "Iswi type complex", "Juxtaparanode region of axon", "Keratin filament", "Kinesin complex", "Kinetochore microtubule", "Lamellar body", "Lamellipodium", "Lamellipodium membrane", "Lamin filament", "Laminin complex", "Large ribosomal subunit", "Late endosome", "Late endosome membrane", "Lateral element", "Lateral part of cell", "Lateral plasma membrane", "Leading edge membrane", "Lewy body", "Lipid droplet", "Lipopolysaccharide receptor complex", "Low density lipoprotein particle", "Lsm1 7 pat1 complex", "Lsm2 8 complex", "Lumenal side of endoplasmic reticulum membrane", "Lumenal side of membrane", "Lysosomal lumen", "M band", "Magnesium dependent protein serine threonine phosphatase complex", "Main axon", "Male germ cell nucleus", "Male pronucleus", "Manchette", "Mcm complex", "Mcrd mediated mrna stability complex", "Mediator complex", "Meiotic cohesin complex", "Meiotic spindle", "Membrane coat", "Membrane microdomain", "Membrane protein complex", "Messenger ribonucleoprotein complex", "Methylosome", "Methyltransferase complex", "Mhc class i peptide loading complex", "Mhc class i protein complex", "Mhc protein complex", "Mib complex", "Micos complex", "Microbody", "Microbody lumen", "Microbody membrane", "Microfibril", "Microtubule", "Microtubule associated complex", "Microtubule bundle", "Microtubule cytoskeleton", "Microtubule end", "Microtubule minus end", "Microtubule organizing center", "Microtubule organizing center attachment site", "Microtubule plus end", "Microvillus", "Microvillus membrane", "Midbody", "Mismatch repair complex", "Mitochondria associated endoplasmic reticulum membrane", "Mitochondrial alpha ketoglutarate dehydrogenase complex", "Mitochondrial crista", "Mitochondrial envelope", "Mitochondrial intermembrane space protein transporter complex", "Mitochondrial large ribosomal subunit", "Mitochondrial matrix", "Mitochondrial permeability transition pore complex", "Mitochondrial protein containing complex", "Mitochondrial proton transporting atp synthase complex coupling factor f o", "Mitochondrial pyruvate dehydrogenase complex", "Mitochondrial small ribosomal subunit", "Mitochondrial tricarboxylic acid cycle enzyme complex", "Mitochondrion", "Mitotic cohesin complex", "Mitotic spindle", "Mitotic spindle astral microtubule", "Mitotic spindle microtubule", "Mitotic spindle midzone", "Mitotic spindle pole", "Mll1 2 complex", "Mll3 4 complex", "Mmxd complex", "Motile cilium", "Mpp7 dlg1 lin7 complex", "Mrna cleavage and polyadenylation specificity factor complex", "Mrna cleavage factor complex", "Mrna editing complex", "Multimeric ribonuclease p complex", "Multivesicular body", "Multivesicular body membrane", "Myelin sheath", "Myelin sheath abaxonal region", "Myelin sheath adaxonal region", "Myofilament", "Myosin complex", "Myosin filament", "Myosin ii complex", "N terminal protein acetyltransferase complex", "Nadh dehydrogenase complex", "Nascent polypeptide associated complex", "Nata complex", "Nbaf complex", "Neurofibrillary tangle", "Neurofilament", "Neuromuscular junction", "Neuron projection", "Neuron projection cytoplasm", "Neuron projection membrane", "Neuron projection terminus", "Neuron spine", "Neuron to neuron synapse", "Neuronal dense core vesicle", "Neuronal ribonucleoprotein granule", "Neurotransmitter receptor complex", "Nlrp3 inflammasome complex", "Nls dependent protein nuclear import complex", "Node of ranvier", "Non motile cilium", "Nonhomologous end joining complex", "Npbaf complex", "Nsl complex", "Nuclear body", "Nuclear chromosome", "Nuclear cyclin dependent protein kinase holoenzyme complex", "Nuclear envelope", "Nuclear envelope lumen", "Nuclear exosome rnase complex", "Nuclear inclusion body", "Nuclear inner membrane", "Nuclear lamina", "Nuclear membrane", "Nuclear outer membrane", "Nuclear outer membrane endoplasmic reticulum membrane network", "Nuclear periphery", "Nuclear pore", "Nuclear pore central transport channel", "Nuclear pore nuclear basket", "Nuclear pore outer ring", "Nuclear protein containing complex", "Nuclear replication fork", "Nuclear rna export factor complex", "Nuclear speck", "Nuclear stress granule", "Nuclear ubiquitin ligase complex", "Nucleocytoplasmic transport complex", "Nucleoid", "Nucleolar ribonuclease p complex", "Nucleolus", "Nucleotide activated protein kinase complex", "Nucleotide excision repair complex", "Nurd complex", "Nurf complex", "Oligosaccharyltransferase complex", "Organellar ribosome", "Organelle envelope lumen", "Organelle inner membrane", "Organelle membrane contact site", "Organelle subcompartment", "Origin recognition complex", "Outer dense fiber", "Outer kinetochore", "Outer membrane", "Outer mitochondrial membrane protein complex", "Oxidoreductase complex", "Oxoglutarate dehydrogenase complex", "P body", "Palmitoyltransferase complex", "Pam complex tim23 associated import motor", "Parallel fiber to purkinje cell synapse", "Paranodal junction", "Paraspeckles", "Pcg protein complex", "Peptidase complex", "Peptidase inhibitor complex", "Pericentric heterochromatin", "Pericentriolar material", "Periciliary membrane compartment", "Perikaryon", "Perinuclear endoplasmic reticulum", "Perinuclear region of cytoplasm", "Perinucleolar compartment", "Phagocytic cup", "Phagocytic vesicle", "Phagocytic vesicle lumen", "Phagocytic vesicle membrane", "Phagolysosome", "Phagophore assembly site", "Phagophore assembly site membrane", "Phosphatase complex", "Phosphatidylinositol 3 kinase complex", "Phosphatidylinositol 3 kinase complex class iii", "Phospholipid translocating atpase complex", "Photoreceptor connecting cilium", "Photoreceptor inner segment", "Photoreceptor outer segment", "Photoreceptor ribbon synapse", "Pi body", "Picln sm protein complex", "Pigment granule", "Pinosome", "Pip body", "Plasma membrane protein complex", "Plasma membrane raft", "Plasma membrane region", "Plasma membrane signaling receptor complex", "Platelet alpha granule", "Platelet alpha granule lumen", "Platelet alpha granule membrane", "Platelet dense granule", "Platelet dense granule lumen", "Platelet dense granule membrane", "Platelet dense tubular network", "Platelet dense tubular network membrane", "Pml body", "Podosome", "Polar microtubule", "Pole plasm", "Polymeric cytoskeletal fiber", "Polysomal ribosome", "Polysome", "Pore complex", "Post mrna release spliceosomal complex", "Postsynapse", "Postsynaptic cytoskeleton", "Postsynaptic cytosol", "Postsynaptic density intracellular component", "Postsynaptic density membrane", "Postsynaptic endocytic zone", "Postsynaptic endosome", "Postsynaptic membrane", "Postsynaptic recycling endosome", "Postsynaptic specialization intracellular component", "Postsynaptic specialization membrane", "Potassium channel complex", "Pre snornp complex", "Precatalytic spliceosome", "Prefoldin complex", "Preribosome", "Preribosome large subunit precursor", "Preribosome small subunit precursor", "Prespliceosome", "Presynapse", "Presynaptic active zone", "Presynaptic active zone cytoplasmic component", "Presynaptic active zone membrane", "Presynaptic cytoskeleton", "Presynaptic cytosol", "Presynaptic endocytic zone", "Presynaptic membrane", "Procentriole replication complex", "Pronucleus", "Protease inhibitor complex", "Proteasome accessory complex", "Proteasome complex", "Proteasome core complex", "Proteasome core complex alpha subunit complex", "Proteasome core complex beta subunit complex", "Proteasome regulatory particle", "Proteasome regulatory particle base subcomplex", "Proteasome regulatory particle lid subcomplex", "Protein acetyltransferase complex", "Protein complex involved in cell adhesion", "Protein dna complex", "Protein kinase complex", "Protein lipid complex", "Protein phosphatase 4 complex", "Protein phosphatase type 1 complex", "Protein phosphatase type 2a complex", "Proton transporting atp synthase complex", "Proton transporting atp synthase complex catalytic core f 1", "Proton transporting atp synthase complex coupling factor f o", "Proton transporting two sector atpase complex", "Proton transporting two sector atpase complex catalytic domain", "Proton transporting two sector atpase complex proton transporting domain", "Proton transporting v type atpase complex", "Proton transporting v type atpase v0 domain", "Proton transporting v type atpase v1 domain", "Proximal dendrite", "Prp19 complex", "Pseudopodium", "Ptw pp1 phosphatase complex", "Pwp2p containing subcomplex of 90s preribosome", "R2tp complex", "Ragulator complex", "Rdna heterochromatin", "Receptor complex", "Recycling endosome", "Recycling endosome membrane", "Replication fork", "Replisome", "Respirasome", "Respiratory chain complex iii", "Respiratory chain complex iv", "Retromer complex", "Ribbon synapse", "Ribonuclease mrp complex", "Ribonuclease p complex", "Ribonucleoprotein complex", "Ribonucleoprotein granule", "Ribose phosphate diphosphokinase complex", "Ribosomal subunit", "Ribosome", "Ripoptosome", "Risc loading complex", "Rna cap binding complex", "Rna polymerase complex", "Rna polymerase i complex", "Rna polymerase ii core complex", "Rna polymerase ii holoenzyme", "Rna polymerase ii transcription regulator complex", "Rna polymerase ii transcription repressor complex", "Rna polymerase iii complex", "Rna polymerase iii transcription regulator complex", "Rnai effector complex", "Rough endoplasmic reticulum", "Rough endoplasmic reticulum membrane", "Rpap3 r2tp prefoldin like complex", "Ruffle", "Ruffle membrane", "Saga complex", "Saga type complex", "Sarcolemma", "Sarcoplasm", "Sarcoplasmic reticulum lumen", "Sarcoplasmic reticulum membrane", "Scar complex", "Scf ubiquitin ligase complex", "Schaffer collateral ca1 synapse", "Sec61 translocon complex", "Secondary lysosome", "Secretory granule", "Secretory granule membrane", "Secretory vesicle", "Seh1 associated complex", "Septin cytoskeleton", "Serine protease inhibitor complex", "Set1c compass complex", "Sex chromatin", "Sex chromosome", "Shelterin complex", "Side of membrane", "Signal peptidase complex", "Signal recognition particle", "Sin3 complex", "Sin3 type complex", "Site of dna damage", "Site of double strand break", "Site of polarized growth", "Sm like protein family complex", "Small ribosomal subunit", "Small subunit processome", "Smc5 smc6 complex", "Smn complex", "Smn sm protein complex", "Smooth endoplasmic reticulum", "Smooth endoplasmic reticulum membrane", "Snare complex", "Sno s rna containing ribonucleoprotein complex", "Sodium potassium exchanging atpase complex", "Somatodendritic compartment", "Sorting endosome", "Spanning component of membrane", "Specific granule", "Specific granule lumen", "Specific granule membrane", "Spectrin", "Spectrin associated cytoskeleton", "Sperm annulus", "Sperm connecting piece", "Sperm fibrous sheath", "Sperm head", "Sperm head plasma membrane", "Sperm midpiece", "Sperm plasma membrane", "Sperm principal piece", "Spermatoproteasome complex", "Spherical high density lipoprotein particle", "Spindle", "Spindle microtubule", "Spindle midzone", "Spindle pole", "Spindle pole centrosome", "Spliceosomal complex", "Spliceosomal snrnp complex", "Spliceosomal tri snrnp complex", "Stereocilia coupling link", "Stereocilium bundle", "Stereocilium membrane", "Stereocilium tip", "Striated muscle thin filament", "Sumo ligase complex", "Supramolecular complex", "Supramolecular polymer", "Swi snf complex", "Swr1 complex", "Synapse", "Synaptic cleft", "Synaptic membrane", "Synaptic vesicle membrane", "Synaptonemal structure", "T tubule", "Telomerase holoenzyme complex", "Terminal bouton", "Tertiary granule", "Tertiary granule lumen", "Tertiary granule membrane", "Tetraspanin enriched microdomain", "Tho complex", "Tight junction", "Tim22 mitochondrial import inner membrane insertion complex", "Tim23 mitochondrial import inner membrane translocase complex", "Tor complex", "Torc1 complex", "Trans golgi network", "Trans golgi network membrane", "Trans golgi network transport vesicle", "Trans golgi network transport vesicle membrane", "Transcription elongation factor complex", "Transcription export complex", "Transcription export complex 2", "Transcription factor tfiid complex", "Transcription factor tfiih holo complex", "Transcription factor tfiiic complex", "Transcription factor tftc complex", "Transcription preinitiation complex", "Transcription regulator complex", "Transcription repressor complex", "Transferase complex", "Transferase complex transferring phosphorus containing groups", "Translation preinitiation complex", "Translocon complex", "Transport vesicle", "Transport vesicle membrane", "Transporter complex", "Trapp complex", "Tricarboxylic acid cycle enzyme complex", "Triglyceride rich plasma lipoprotein particle", "Trna methyltransferase complex", "Trna splicing ligase complex", "Tubular endosome", "U1 snrnp", "U12 type spliceosomal complex", "U2 snrnp", "U2 type catalytic step 2 spliceosome", "U2 type spliceosomal complex", "U2af complex", "U4 snrnp", "U5 snrnp", "U6 snrnp", "U7 snrnp", "Ubiquitin conjugating enzyme complex", "Ubiquitin ligase complex", "Unconventional myosin complex", "Uniplex complex", "Vacuolar lumen", "Vacuolar membrane", "Vacuolar proton transporting v type atpase v0 domain", "Vacuole", "Varicosity", "Vcp npl4 ufd1 aaa atpase complex", "Vesicle coat", "Vesicle lumen", "Vesicle membrane", "Vesicle tethering complex", "Voltage gated calcium channel complex", "Wash complex", "Weibel palade body", "Wnt signalosome", "X chromosome", "Xy body", "Zona pellucida receptor complex", "Zonula adherens", "Zymogen granule", "Zymogen granule membrane"], "available_proteins": ["AAAS", "AAGAB", "AAK1", "AAMP", "AAR2", "AARS", "AARS2", "AASS", "AATF", "ABCB1", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABHD10", "ABHD11", "ABHD12", "ABHD14B", "ABHD6", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ADA", "ADAM17", "ADAR", "ADD1", "ADD3", "ADH5", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKT1", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG13", "ALG5", "ALKBH1", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APC", "APEH", "APEX1", "API5", "APMAP", "APOBEC3C", "APOO", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP3", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGAP35", "ARHGAP5", "ARHGDIA", "ARHGEF2", "ARID1A", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL6IP5", "ARL8B", "ARMC1", "ARMC10", "ARMC9", "ARMCX3", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARVCF", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD3A", "ATAD3B", "ATAD5", "ATF7IP", "ATG3", "ATG9A", "ATL2", "ATL3", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATRX", "ATXN10", "ATXN2", "ATXN2L", "AUP1", "B3GALT6", "B4GALT1", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BCAP31", "BCAS2", "BCAT2", "BCCIP", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BDH2", "BICD2", "BIRC6", "BLM", "BLOC1S1", "BMS1", "BNIP1", "BOD1L1", "BOLA2*", "BOP1", "BPTF", "BRAP", "BRCA1", "BRD2", "BRD4", "BRI3BP", "BRIX1", "BSG", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "C12orf43", "C12orf73", "C14orf2", "C19orf70", "C1QBP", "C1orf35", "C21orf59", "C2CD5", "C2orf49", "CAB39", "CACTIN", "CACYBP", "CAD", "CADM1", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CANX", "CAP1", "CAP2", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CASK", "CASP2", "CASP3", "CAST", "CBL", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC124", "CCDC22", "CCDC47", "CCDC51", "CCDC86", "CCDC88A", "CCDC93", "CCDC94", "CCNA2", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC23", "CDC25C", "CDC27", "CDC37", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP3", "CDK6", "CDKAL1", "CDKN2A", "CDKN2AIP", "CDS2", "CDX2", "CEBPZ", "CECR2", "CELF1", "CENPB", "CENPE", "CENPI", "CENPU", "CENPV", "CEP170", "CEP250", "CEP44", "CEP55", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHCHD4", "CHD1", "CHD4", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP4A", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHP1", "CHRAC1", "CHST14", "CHTF18", "CHTF8", "CHTOP", "CHUK", "CIAPIN1", "CIRBP", "CISD2", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLN6", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLSPN", "CLTA", "CLTC", "CLU", "CMPK1", "CNN2", "CNN3", "CNOT1", "CNOT11", "CNOT3", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG2", "COG3", "COG4", "COG7", "COIL", "COLEC12", "COLGALT1", "COMMD1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "CORO1B", "CORO1C", "COTL1", "COX11", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRK", "CRKL", "CRNKL1", "CRTAP", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CTTNBP2NL", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC15", "CWC22", "CWF19L1", "CXorf57", "CYB5B", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF7", "DCAF8", "DCP1A", "DCP1B", "DCP2", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENND4C", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHODH", "DHRS1", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DIS3L2", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNTTIP2", "DOCK7", "DOLPP1", "DPF2", "DPM1", "DPP9", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTL", "DTYMK", "DUSP3", "DUT", "DVL2", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EGFR", "EHBP1", "EHD1", "EHD4", "EHMT2", "EIF2A", "EIF2AK2", "EIF2AK4", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5A", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP4", "EMC1", "EMC2", "EMC3", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L5", "EPDR1", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESS2", "ESYT1", "ESYT2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6B", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXTL3", "EZR", "F11R", "FABP5", "FAF1", "FAF2", "FAHD1", "FAM114A1", "FAM118B", "FAM160A2", "FAM162A", "FAM208A", "FAM49B", "FAM83D", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FBL", "FBXO22", "FDFT1", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP1A", "FKBP2", "FKBP4", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNBP4", "FNDC3A", "FNTA", "FNTB", "FOXRED1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FUNDC2", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLM", "GCN1", "GDAP1", "GDAP2", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GEMIN8", "GET4", "GFM1", "GGA1", "GGCX", "GGH", "GHDC", "GHITM", "GID4", "GID8", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG5", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM1", "GOLPH3", "GOLPH3L", "GOLT1B", "GOPC", "GORASP2", "GOT2", "GPAM", "GPATCH4", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR108", "GPR89B", "GPS1", "GPSM1", "GPT2", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSR", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTSE1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAGH", "HARS2", "HAT1", "HAUS1", "HAUS2", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HAX1", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDHD5", "HDLBP", "HEATR1", "HELLS", "HERC4", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HM13", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGN1", "HMGN2", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HOXD13", "HP1BP3", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA6", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HUS1", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IER3IP1", "IFIT5", "IFNGR1", "IFT27", "IFT88", "IGF1R", "IGF2BP1", "IGF2BP3", "IGF2R", "IK", "IKBIP", "IKBKB", "IKBKG", "ILF2", "ILF3", "ILK", "ILVBL", "IMMT", "IMP3", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS11", "INTS12", "INTS13", "INTS14", "INTS3", "INTS7", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "ISCU", "ISG20L2", "ISOC1", "IST1", "ISY1", "ITCH", "ITGB1", "ITSN2", "IVD", "JAGN1", "JMJD6", "JUP", "KARS", "KAT7", "KCTD12", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KDSR", "KHDRBS1", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1468", "KIF11", "KIF14", "KIF15", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "L2HGDH", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDHA", "LDHB", "LDLR", "LDLRAP1", "LEMD2", "LEMD3", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRP1", "LRPAP1", "LRPPRC", "LRRC59", "LRWD1", "LSM14A", "LSM2", "LSM6", "LSS", "LTA4H", "LTV1", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LZTS2", "M6PR", "MACF1", "MAD1L1", "MAGED1", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP4", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARK1", "MARK2", "MARS", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MEAF6", "MECP2", "MED1", "MED14", "MED16", "MED21", "MED23", "MED24", "MED4", "MEPCE", "METTL1", "METTL13", "METTL3", "MFAP1", "MFF", "MFN1", "MFN2", "MFSD10", "MGAT1", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MICALL1", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MKLN1", "MLEC", "MMAB", "MMGT1", "MMS19", "MOB4", "MOGS", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRC2", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL22", "MRPL23", "MRPL28", "MRPL3", "MRPL37", "MRPL39", "MRPL4", "MRPL40", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL50", "MRPL55", "MRPL58", "MRPL9", "MRPS10", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTERF3", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR2", "MTOR", "MTPAP", "MTSS1L", "MTX1", "MTX2", "MTX3", "MUT", "MVK", "MXRA7", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA16", "NAA35", "NAA40", "NAA50", "NADK2", "NAGLU", "NAMPT", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCDN", "NCKAP1", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "ND5", "NDC1", "NDC80", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEFL", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NENF", "NES", "NFKB1", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NISCH", "NIT2", "NKRF", "NLE1", "NLN", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NPC1", "NPC2", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NRDE2", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSUN2", "NSUN5", "NT5C3A", "NUB1", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT16", "NUDT21", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NVL", "NXF1", "OAT", "OCIAD1", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAIP1", "PAK1", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PARG", "PARK7", "PARN", "PARP1", "PATL1", "PAXIP1", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCM1", "PCNA", "PCNP", "PCNT", "PCYOX1", "PDAP1", "PDCD11", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXDC1", "PDXK", "PDZD8", "PECR", "PEF1", "PELP1", "PES1", "PEX14", "PEX19", "PEX5", "PFDN1", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGGT1B", "PGK1", "PGM1", "PGM2", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF2", "PHF5A", "PHF6", "PHF8", "PHIP", "PI4K2A", "PI4KA", "PI4KB", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIH1D1", "PIK3C2A", "PIK3C3", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2B", "PISD", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCB3", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNISR", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "PON2", "POP1", "POR", "PPA2", "PPAN", "PPFIA1", "PPHLN1", "PPIB", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKAR2B", "PRKCD", "PRKCSH", "PRKDC", "PRMT1", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF39", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PSAP", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTK7", "PTPA", "PTPN1", "PTPN23", "PTPN9", "PTPRF", "PTRH2", "PUM1", "PUM3", "PURA", "PUS1", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "PYM1", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABEP1", "RABEPK", "RABGAP1", "RABGGTA", "RABGGTB", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RANGRF", "RAP1GDS1", "RAPGEF2", "RAPGEF6", "RARS", "RARS2", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM5", "RBM8A", "RBMX", "RBPMS", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "RECQL5", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RINT1", "RIOX1", "RIOX2", "RIPK1", "RMDN1", "RMND5A", "RNASEH2A", "RNASEH2B", "RNASET2", "RNF14", "RNF20", "RNF219", "RNF40", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCB", "RTF1", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SACS", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAR1A", "SAR1B", "SARNP", "SARS2", "SART1", "SART3", "SASS6", "SBDS", "SCAF1", "SCAF11", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCRIB", "SCRN1", "SCYL2", "SDAD1", "SDCBP", "SDF2L1", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD7", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL2", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHCBP1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIN3A", "SIRT1", "SKA1", "SKA3", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A5", "SLC25A6", "SLC27A4", "SLC30A7", "SLC35A4", "SLC35B2", "SLC38A2", "SLC3A2", "SLC6A15", "SLC9A3R1", "SLFN11", "SLIRP", "SLK", "SLTM", "SLU7", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SNAP23", "SNAP29", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC24", "SPC25", "SPCS2", "SPDL1", "SPECC1", "SPECC1L", "SPEN", "SPHK2", "SPNS1", "SPOUT1", "SPPL2A", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX4", "STX6", "STX7", "STX8", "STXBP2", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE1", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACC3", "TACO1", "TADA3", "TAF15", "TAMM41", "TAP1", "TARDBP", "TARS2", "TBC1D10A", "TBC1D17", "TBCA", "TBCB", "TBCC", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TBL3", "TBRG4", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TCP11L1", "TDRD7", "TDRKH", "TECR", "TELO2", "TERF2", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGS1", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM17A", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TIMM9", "TIMMDC1", "TJP1", "TJP2", "TKT", "TLN1", "TM9SF2", "TM9SF4", "TMA16", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM11", "TMEM126A", "TMEM126B", "TMEM165", "TMEM192", "TMEM199", "TMEM201", "TMEM206", "TMEM214", "TMEM230", "TMEM30A", "TMEM33", "TMEM43", "TMEM59", "TMEM63A", "TMEM87A", "TMEM97", "TMF1", "TMLHE", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOM1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRIM21", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIO", "TRIP12", "TRIP13", "TRMT10C", "TRMT112", "TRMT6", "TRMU", "TROVE2", "TRUB1", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN10", "TSPAN3", "TSPAN6", "TSPO", "TSPYL1", "TSR1", "TTC1", "TTC19", "TTC26", "TTC28", "TTC37", "TTF2", "TTI1", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNG", "TXN2", "TXNDC12", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UBA1", "UBA2", "UBA5", "UBAC1", "UBAP2", "UBAP2L", "UBE2G2", "UBE2K", "UBE2L3", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE2T", "UBE3A", "UBE3C", "UBE4A", "UBLCP1", "UBP1", "UBQLN1", "UBQLN2", "UBQLN4", "UBR1", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UFD1", "UFL1", "UFSP2", "UGCG", "UGGT1", "UHRF1", "UNC119B", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP15", "USP28", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "UXT", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VPS13A", "VPS18", "VPS25", "VPS26A", "VPS26B", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37C", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK2", "VTA1", "VTI1B", "WAPL", "WARS2", "WASHC3", "WASHC5", "WASL", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR36", "WDR4", "WDR41", "WDR43", "WDR45B", "WDR46", "WDR48", "WDR5", "WDR61", "WDR70", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WRAP53", "WRAP73", "WTAP", "XAB2", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YAP1", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YEATS4", "YIF1A", "YIPF4", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF1", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H14", "ZC3H18", "ZC3HC1", "ZCCHC11", "ZCCHC8", "ZCRB1", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM2", "ZMYND8", "ZNF326", "ZNF622", "ZNF638", "ZPR1", "ZSWIM8", "ZW10", "ZWILCH", "ZYX"], "leading_proteins": ["ABCB1", "ABHD10", "ABHD12", "ACAT2", "ACBD5", "ACOX1", "ACP2", "ACP6", "ACTR1A", "ADAM17", "ADPGK", "AGK", "AGPS", "AIFM1", "AKAP8", "AKAP9", "AKT1", "ALDH3A2", "ANAPC16", "ANAPC2", "ANAPC7", "ANK3", "ANKLE2", "ANXA1", "ANXA11", "ANXA7", "AP3M1", "APC", "APOBEC3C", "APOO", "ARF4", "ARF5", "ARFIP2", "ARL2", "ARL6IP1", "ARMC10", "ARMCX3", "ASAH1", "ASNA1", "ATG9A", "ATL2", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP2A2", "ATP2B1", "ATP5L", "ATP6", "ATP6V0A1", "ATP6V0A2", "ATPIF1", "B4GALT1", "B4GAT1", "BABAM2", "BAIAP2", "BAX", "BCL2L13", "BICD2", "BRCA1", "BSG", "BUB1B", "C12orf73", "C19orf70", "C1QBP", "CACYBP", "CALM3", "CALU", "CAPN2", "CAPZB", "CASK", "CASP3", "CCDC47", "CCDC51", "CCNA2", "CCT2", "CDCA8", "CDK4", "CDK5", "CDKAL1", "CDS2", "CENPE", "CERS2", "CHCHD3", "CHCHD4", "CHMP1A", "CHMP5", "CHST14", "CHUK", "CIRBP", "CKAP4", "CLCC1", "CLCN3", "CLN5", "CLPP", "CLPTM1", "CLU", "COA3", "COG3", "COLEC12", "COPS4", "COPS5", "COQ8A", "CORO1C", "COX11", "COX15", "COX5A", "COX7A2", "CPNE1", "CPPED1", "CPT2", "CRK", "CRTAP", "CSTB", "CTNND1", "CTSA", "CTSB", "CTSC", "CYB5B", "CYFIP1", "CYP51A1", "DBN1", "DCAF8", "DCTN2", "DCTN4", "DCTPP1", "DDX3X", "DERL1", "DHCR24", "DHCR7", "DHFR", "DIABLO", "DNA2", "DNAJC1", "DNAJC2", "DNM1L", "DOLPP1", "DVL2", "DYM", "EBP", "ECE1", "ECI1", "EIF2B2", "EIF2B3", "EIF2B5", "EIF4E", "EIF4H", "EIF5A", "EMD", "EPDR1", "EPHX1", "ERAP1", "ERGIC3", "ERMP1", "ETFDH", "EXTL3", "FABP5", "FAM162A", "FAM49B", "FASN", "FASTKD2", "FDFT1", "FKBP10", "FKBP14", "FKBP1A", "FKBP2", "FKBP4", "FKBP7", "FLAD1", "FMR1", "FOXRED1", "FUCA1", "FUCA2", "FXR1", "FXR2", "GAA", "GADD45GIP1", "GBA", "GEMIN4", "GEMIN8", "GGCX", "GGH", "GHITM", "GIGYF2", "GLA", "GM2A", "GNPAT", "GOLIM4", "GOLPH3", "GPR107", "GPR108", "GPR89B", "GRB2", "GUSB", "GYG1", "HACD3", "HADH", "HAUS1", "HAUS2", "HAUS3", "HAUS4", "HAUS5", "HCCS", "HDGF", "HK2", "HLA-A", "HLA-B", "HLA-C", "HMOX1", "HMOX2", "HNRNPA3", "HNRNPAB", "HNRNPD", "HNRNPH2", "HNRNPK", "HNRNPR", "HPS6", "HS2ST1", "HSD17B12", "HSDL1", "HSPA6", "HTT", "IARS2", "ICMT", "IDH1", "IDH2", "IFNGR1", "IGF2R", "ILVBL", "INA", "INCENP", "IPO7", "IPO8", "IQGAP2", "ISOC1", "JAGN1", "KCTD12", "KDELR1", "KDELR3", "KDSR", "KIAA0319L", "KIAA1468", "LAMC1", "LAMTOR2", "LBR", "LDLRAP1", "LGALS3BP", "LMAN1", "LMAN2", "LMF2", "LNPEP", "LSM6", "LSS", "LTA4H", "M6PR", "MAIP1", "MAN1A2", "MAPK1", "MAPRE2", "MED14", "MED21", "MFN2", "MGAT1", "MIA2", "MIF", "MINDY3", "MIPEP", "MLEC", "MMGT1", "MOV10", "MPC2", "MPP2", "MPP7", "MPV17L2", "MRPL10", "MRPL2", "MRPL28", "MRPL40", "MRPL43", "MRPL45", "MRPL55", "MRPS11", "MRPS18A", "MRPS5", "MRPS9", "MSMO1", "MSTO1", "MTCH1", "MTCH2", "MTFP1", "MXRA7", "MYH14", "MYH9", "MYL6", "MYO18A", "NAA40", "NAGLU", "NAP1L1", "NCLN", "NCSTN", "NDC1", "NDUFA11", "NDUFAF2", "NDUFB1", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS2", "NEFL", "NENF", "NISCH", "NLN", "NPC1", "NPC2", "NPTN", "NSUN2", "NT5C3A", "NUCB1", "NUCB2", "NUDT12", "OLA1", "OPA1", "OPA3", "OSBPL3", "OXA1L", "P3H1", "P3H4", "P4HA1", "P4HA2", "PABPC1", "PABPC4", "PCM1", "PCYOX1", "PDCD6", "PDCL3", "PDK3", "PECR", "PELP1", "PFDN1", "PFDN2", "PFN2", "PGRMC1", "PGRMC2", "PI4KA", "PI4KB", "PIGL", "PIN4", "PITRM1", "PLA2G15", "PLBD2", "PLD3", "PLK1", "PLOD3", "POLA2", "POLDIP2", "POLE3", "POLE4", "POLR2E", "PON2", "POP1", "PPP2R1A", "PPP2R1B", "PPT1", "PPT2", "PQBP1", "PRCP", "PRDX3", "PREPL", "PSAP", "PSMA1", "PSMA6", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMG1", "PTGES2", "PTPRF", "PXMP2", "RAB1B", "RAB24", "RAB34", "RAB5B", "RAB5C", "RABEPK", "RAD23A", "RALA", "RBM4", "RBMX", "RBPMS", "RCN2", "REEP3", "REEP4", "RMND5A", "RNF20", "RPS28", "RRM2B", "RTN1", "RTN3", "RTN4", "SAMM50", "SCARB1", "SCARB2", "SCCPDH", "SCO1", "SEC11A", "SEC16A", "SEC23IP", "SEPT6", "SEPT7", "SET", "SFXN2", "SFXN4", "SGPL1", "SHMT2", "SIGMAR1", "SLC12A2", "SLC16A1", "SLC19A1", "SLC25A10", "SLC25A11", "SLC25A13", "SLC25A15", "SLC25A20", "SLC25A24", "SLC25A26", "SLC25A32", "SLC25A33", "SLC25A4", "SLC38A2", "SNAP29", "SNX12", "SNX27", "SNX5", "SNX9", "SORT1", "SPART", "SPDL1", "SPECC1L", "SPHK2", "SPPL2A", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC2", "SQLE", "SRPRB", "SSBP1", "SSR1", "STAM", 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1.21997288878307 0.3503559587509399 5.621054768990946 6.443005397350486 1.219878183292811 0.3773673755377006 0.0061962212919642 0.0007314420471733 0.0005525090849858 0.0096737093303352 0.0275610661694587 +Threonine type peptidase activity 5 10 2.609443463168119 0.0090689630535261 3.8106796116504857 8.762135922330097 1.392634148189787 0.2146040118876429 1.6274593113109357 0.6695334565847216 1.0340073360925757 0.2572219198248905 0.0053320059864036 1.0 0.0078714328443906 4.971597541903914e-07 2.8278124161204832e-05 +Macrolide binding 5 7 2.5850154313922715 0.0097374639180356 1.983009708737864 6.422330097087379 0.7710035079475605 0.4104541026784208 1.4588872837549367 0.7512361384385784 1.0178387667233504 0.3228401619923597 5.568522345612659e-05 1.2998708524751297e-05 1.6794521031150823e-06 3.77413242971045e-08 2.339885859608748e-06 +Fk506 binding 5 7 2.5850154313922715 0.0097374639180356 1.983009708737864 6.422330097087379 0.7710035079475605 0.4104541026784208 1.4588872837549367 0.7512361384385784 1.0178387667233504 0.3228401619923597 3.920424281098301e-05 9.130642966886304e-06 1.0152328729907457e-06 1.5409886188351435e-08 9.76257263135182e-07 +Steroid binding 8 22 2.5827139039782336 0.0098026574241363 8.424757281553399 21.398058252427184 1.4469817519716153 0.1523451695819165 3.035656818503787 2.066091501771892 1.85140774519605 0.2395996334984524 0.0576595399456432 1.0 0.0818055658939264 0.0001661825272043 0.000525961744528 +Organic acid transmembrane transporter activity 8 21 2.5754787340884007 0.0100101428672674 8.592233009708737 21.276699029126213 1.5973629153049684 0.1905568538747131 4.4420473133518055 2.549726956007885 1.3213968531498468 0.2647933566957936 0.0167187669014934 0.2849410889163232 0.0042348756279302 0.0246198078338957 0.0055572149230821 +Metallopeptidase activity 18 43 2.570133007838625 0.0101659475209017 11.548543689320388 40.60436893203884 1.2053444242445344 0.3510417366391842 4.586289489033314 2.1135899474190585 1.0988837346562612 0.3462572593421246 0.4730112909316188 0.326192706464958 0.0426450873703444 0.0130864958075334 2.82391615026485e-05 +Threonine type endopeptidase activity 4 8 2.559950887729327 0.0104686956440109 3.7135922330097086 7.970873786407767 1.4913184573846054 0.1902243906475925 1.515457478026574 0.1681602725795027 1.0170822776023185 0.2455850375425174 0.002691599026727 1.0 0.0039921150854813 1.8654270901726772e-06 5.5966724052351854e-05 +Exopeptidase activity 14 32 2.54831093284624 0.0108245944086231 9.74514563106796 31.84223300970874 1.193034763402526 0.2308543476384821 3.0338864063053523 1.9513159274241312 1.6646797512653713 0.2911825093455628 0.0124899012293659 0.0358926009784828 2.5950305544608952e-05 0.0001057601199578 9.909266056963585e-07 +Isomerase activity 9 70 2.5092438059775857 0.0120989944849589 18.781553398058257 68.51456310679612 -0.6794453818373789 0.5075954493054885 8.34980666682542 6.586782996730463 0.8199310187929079 0.3256160286425522 0.0039351480988732 0.0039003874446117 0.0017603177505407 0.0014036166596972 0.0122861154963721 +Transferase activity transferring alkyl or aryl other than methyl groups 4 24 2.5051942681173616 0.0122384152788681 6.269417475728155 21.9004854368932 0.1637295171124019 0.5810042550406141 3.4221915209842564 3.50274507569733 0.8797870134307709 0.3068689904123456 0.0456351184097705 0.0187248462666395 0.0651781855152293 0.0037016693244557 0.0172802721197194 +Transporter activity 50 166 2.501329210286787 0.0123728104074025 62.22330097087379 172.27912621359224 2.173366592838491 0.2707201784543502 25.984753572620328 19.29276868436311 2.593156143256053 0.3916539604106395 5.132724430594264e-05 0.0034618551252646 0.0001336787924137 8.666303831563852e-06 2.697283043861513e-06 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen 11 33 2.4392485006168303 0.0147178434308792 9.395631067961164 29.8373786407767 1.5709767518568172 0.2393367467664754 3.119976403291062 3.762391942431812 1.2135099906711824 0.3124947384976632 0.0376264801550078 0.0760657989123155 0.0616304522136525 0.0004182953821198 0.001821835634791 +Protein transporter activity 3 14 2.3743701143651603 0.0175789197585098 6.053398058252427 14.696601941747574 1.6882240898296943 0.1359359142649309 2.957968193176 1.443999336657768 1.4805047019217734 0.2345897542974644 0.0166138820171136 0.0065792573185243 0.02421661276018 0.0028897230126965 0.0314674363117242 +Cation transmembrane transporter activity 17 65 2.3724572520434486 0.0176702077357602 25.62135922330097 70.51699029126213 1.766742880952279 0.2698419237572138 12.29126021871486 8.422243011776631 2.00238274385689 0.3706372466673562 0.1114298519505726 0.0262221556449147 0.186637380486808 0.0557248514843523 0.0599346502527403 +Metalloendopeptidase activity 8 15 2.3601168829482777 0.0182691779044801 5.449029126213592 14.364077669902912 1.4597326207035937 0.2246869419023046 2.4848715129851016 0.6671711573432166 0.9390012824303952 0.2775881383017788 1.0 1.0 0.2756599666896902 0.0453869127531283 0.0047299686256361 +Protein transmembrane transporter activity 2 10 2.352500322209689 0.0186476736133278 4.37621359223301 11.264563106796116 1.6409152716253632 0.1284874270119089 2.3258190399954897 0.995332092405782 1.387057072324357 0.2266762256512647 0.0078467631279172 0.0030581061915538 0.0115435449528709 0.0075105395483816 0.0472723399635447 +Inorganic molecular entity transmembrane transporter activity 35 72 2.3231145815578897 0.0201729978500062 28.058252427184467 75.9635922330097 1.5031303400189615 0.2894264293069549 11.721339963426631 9.38477049228959 2.153051736566399 0.3821536813265525 0.3041645020278734 0.7015093355770722 0.4212341663856208 0.0729740867776155 0.0289498962959742 +Nadp binding 4 17 2.3181604436329737 0.0204406029403705 3.966019417475728 17.985436893203882 0.66085030998649 0.497161667914878 2.1141710210905544 1.9470619024167608 0.8006079385844883 0.3067322240884021 0.002632380771776 0.012648542478749 0.0003475618019176 0.001461517407229 0.0263404288632578 +Secondary active transmembrane transporter activity 5 18 2.2947466961377403 0.0217476450170521 9.080097087378642 21.490291262135923 1.2627683473613005 0.2947710034053126 5.466215032972134 3.0675886156990426 1.4241587428281404 0.3340388164945335 0.5058485752328652 1.0 0.5778229381468787 0.6354410156141544 0.2594832759483197 +Sphingolipid binding 3 6 2.2867173783973422 0.0222123246762409 3.2305825242718447 6.810679611650485 1.3881601090528384 0.1287371848492678 1.3662849673921555 1.293404675510669 1.5116584105270494 0.2146285912590262 0.0087823993506393 1.0 0.012905013470629 0.0007989256016515 0.0099569143851569 +Transmembrane transporter binding 9 32 2.284210178870303 0.0223591816425472 6.233009708737864 30.356796116504853 0.2286793094831162 0.6608453659958601 3.699787145530921 3.1778018639598757 0.6794318171135323 0.2958932397602019 0.1221149024095898 0.312708212996757 0.0375044006736284 0.1135382716428265 0.0770198920563529 +Macromolecule transmembrane transporter activity 3 11 2.278946914254816 0.0226702211482587 4.820388349514563 12.281553398058252 1.6605285757306012 0.1306403746261988 2.4754663863133306 1.0160601209961664 1.3599823000893485 0.2280235038874096 0.0107949235467619 0.0042324529563037 0.0158256043387446 0.0119341177484456 0.0145952588649919 +Serine type exopeptidase activity 4 7 2.2755599745197954 0.0228723592392765 3.783980582524272 6.997572815533981 1.020609253431403 0.1137432544246352 1.3363606860118669 0.0492066381861973 1.87035730934538 0.1990592265121372 0.0021644162661245 0.0432957136582515 1.0152328729907457e-06 3.9104524570814734e-05 2.915330495677531e-05 +Ceramide binding 3 5 2.227158314952556 0.0259366949666968 2.8228155339805827 5.048543689320389 1.42330045764979 0.1242195400491618 1.17628831869178 0.9309003969609838 1.481980135982154 0.2133994029014766 0.0045938733324923 1.0 0.0067896670197663 0.0002054625318554 0.0028246814840344 +Mhc protein complex binding 0 8 2.2215559916427563 0.0263133267864228 3.150485436893204 7.83252427184466 0.0317068288488 0.6044209283427963 2.3320632885551693 0.4164230915288565 0.82337950035524 0.3032257106844406 0.1057194663998679 1.0 0.1277572387780678 0.2917500038862815 0.5041689495301098 +Nucleobase containing compound transmembrane transporter activity 4 12 2.212258813181303 0.0269487871845763 6.529126213592233 14.04126213592233 1.4296604886183193 0.212054291115069 3.2696940585469636 1.915888183904924 1.3255809572534116 0.2748813593420038 0.0020293109696955 1.0 0.0035907130786718 0.0419909810254146 0.0184039293757648 +Molecular transducer activity 14 37 2.211560618622604 0.0269970390376192 10.91747572815534 33.40533980582524 1.343848990749489 0.2329582295822712 4.7124072380860955 5.830391636254363 1.6098335072319665 0.2956883791113679 0.611901955584856 0.7232426124859228 0.7191753660376338 0.438894490287224 0.611709281835572 +Sterol binding 5 17 2.211017633540232 0.0270346159843133 5.495145631067961 16.27912621359223 1.1610523788441311 0.1592175050218891 2.159304933149918 1.9111962434971217 1.7231989277496158 0.231586711794193 0.0329878058874648 1.0 0.0474859144951228 0.0109251570181746 0.0073521738882127 +Nucleotide transmembrane transporter activity 3 10 2.2073051346480383 0.027292748827892 5.606796116504855 12.029126213592232 1.4217258291760082 0.2036087501116975 3.0234925518113496 1.8899648667798992 1.291115513359647 0.2666064512499804 0.0005794505076546 1.0 0.0010401540441919 0.0136772183990335 0.0173495207202435 +Organophosphate ester transmembrane transporter activity 3 10 2.2073051346480383 0.027292748827892 5.665048543689321 12.143203883495143 1.4298365636921646 0.2056324024803549 3.029697948284232 1.927415248708952 1.2819429632405106 0.2680490563295835 0.0006671136126396 1.0 0.0011959433226113 0.0155574138143109 0.0204068190514482 +Cholesterol binding 5 14 2.206136721858533 0.0273744282220445 5.25 13.29126213592233 1.1679703080780182 0.1357521674166823 1.9454015982929531 1.7674569958716484 1.7544522374432017 0.2116991383290636 0.0234831618980058 1.0 0.03403446937649 0.0056932223374956 0.0028701063805994 +Serine type carboxypeptidase activity 4 5 2.201811323892824 0.0276786388565115 3.0558252427184467 4.997572815533981 1.0019911760482532 0.1105835516254352 1.1231414198895626 0.0492066381861973 1.8086551291944464 0.1930654928989846 0.0006137805641373 0.0242848323540905 4.151068855161726e-08 1.6763230163867931e-06 2.7269453249964204e-07 +Signaling receptor regulator activity 2 17 2.194668287519586 0.0281874011497775 4.072815533980583 17.339805825242717 0.7311308082630681 0.4520633016494398 2.421493327854957 2.496807274147909 0.9157780911218903 0.317372323464707 0.1142884986871186 0.0496758524768897 0.1579906452537346 0.5335587935482642 0.4808642038976582 +Palmitoyl protein hydrolase activity 3 6 2.171787251702149 0.0298717136971113 1.91747572815534 5.429611650485437 0.9780254626091984 0.222941388490727 1.137611804765983 0.8139540579221628 1.3123017012345466 0.2566673774233151 0.091321621191287 0.0573151884822011 0.0057815105752346 0.0001450038876457 0.0020333503076747 +Dioxygenase activity 6 23 2.1323933170383023 0.0329745263271439 4.966019417475728 18.946601941747577 0.431149201997438 0.5860948271154753 2.499283524441613 3.0888246903576806 0.809438844885216 0.3223440754880037 0.1015582243289768 0.0437266531990119 0.1411421437582085 0.0060584295805293 0.0473183813132007 +Prenyltransferase activity 3 7 2.1063946965499296 0.0351700815970517 2.099514563106796 6.009708737864078 0.6003375563696288 0.3888587975741492 1.4081247453019228 2.026499903013553 1.0962032128239394 0.3008779016140248 0.1128336603904996 0.0711332726649859 0.1362380906066266 0.005208827916976 0.004988841333209 +Smad binding 1 13 2.0924296033777043 0.0364001029384613 4.531553398058253 13.330097087378642 -0.1364409465066789 0.6699783482716913 3.0171796955285597 1.6816447653376838 0.6970879849785732 0.2887491510625554 0.371181177773541 0.2486824788491954 0.4330643878145832 0.4139938852214621 0.782916165856984 +Antiporter activity 3 9 2.081241778019373 0.0374117813138015 4.621359223300971 10.405339805825244 1.056576117278179 0.2813324268221227 2.679901841610502 1.304685592846984 1.2558310293487471 0.3063102364368053 0.2677608232760495 1.0 0.3169879022746943 0.2450354162713742 0.120966113106861 +Modified amino acid binding 3 23 2.080040423048618 0.0375218253367117 4.446601941747573 21.354368932038835 0.8157790161756342 0.4133026066112408 2.099367243274066 1.7995833767593454 0.9656025978141096 0.3166170247143811 0.0064607496534732 0.0230307909850112 0.0111977735740575 0.0288174339548508 0.0835081281085846 +Iron ion binding 8 27 2.036088907146299 0.0417414284285366 6.524271844660194 22.196601941747577 0.9076096695164306 0.382669917893863 2.4429198675966717 3.289094676807881 0.9378690899634522 0.3126784916965753 0.3861348376523477 0.2597451867723493 0.4495131201040838 0.0006589165548416 0.002642412748723 +Glycolipid binding 2 9 2.034264835220888 0.0419249006431605 3.95873786407767 9.17233009708738 1.1300394975336625 0.1723818604496332 1.779261971800237 1.789101691327159 1.517965150696512 0.2390589148665743 1.0 1.0 1.0 0.0075105395483816 0.0472723399635447 +Solute anion antiporter activity 2 5 2.0326674657093715 0.0420861303644133 2.3737864077669903 5.444174757281553 0.825822657258252 0.3439291028288794 1.663745987721657 0.8585888447978746 1.0247623924866192 0.2999489358207081 0.0840370854942358 1.0 0.1018169846714528 0.0280420066437826 0.0142438301551866 +Glutathione transferase activity 1 8 2.027820896174932 0.042578530862992 2.388349514563106 7.058252427184466 -0.0343576890242698 0.5012486650417416 1.627929829054375 0.961140531216188 0.972915170615138 0.2930270921886944 0.091321621191287 0.0573151884822011 0.1105474823156849 0.0331187861076589 0.1137231346556503 +Nadph binding 1 5 2.02325431160115 0.0430469347346733 1.3786407766990292 5.429611650485437 0.8367704566864596 0.3914568233833007 1.0938176207501296 1.2950229014206938 0.8806674554162238 0.2962147259816868 0.0053320059864036 0.0020655426456597 0.0078714328443906 0.0442367692127036 0.1472320281277068 +Alcohol binding 5 16 2.016703177454996 0.043726498151009 5.70873786407767 16.094660194174757 1.0972550148478282 0.1642412137618775 2.3364194162363723 2.1334758164294443 1.72577974721897 0.2306417307890987 0.05976040377596 1.0 0.0846927074465841 0.0328601744798646 0.0339036808230292 +Growth factor receptor binding 5 21 2.008451408865862 0.0445953446357392 5.233009708737864 16.303398058252426 0.6012049824390195 0.4932334837741021 2.455245557470486 2.477606131434232 0.8745174126419827 0.327387299755004 1.0 1.0 0.0995728547031488 0.1492939653041362 0.0505698485029352 +Channel regulator activity 1 20 2.00663642943837 0.0447883894155101 4.783980582524272 15.990291262135925 0.0369609692667819 0.5929843198395084 2.4023523422516506 2.637464013028564 0.8201394905149542 0.2901418796271611 0.371181177773541 0.2486824788491954 0.4330643878145832 0.4139938852214621 0.782916165856984 +Fad binding 3 8 1.9850063951421268 0.0471437599923778 3.78883495145631 9.932038834951456 1.575439945642976 0.1698004033102896 1.8828741719818296 1.250336932628077 0.9196006746446306 0.2289411404885479 0.1874940936179018 0.1201219647894398 0.2243071172363204 0.0244664942800011 0.0357999050404339 +Translation repressor activity 4 10 1.9786442436679663 0.0478560745924241 2.621359223300971 8.691747572815533 0.8178109552751379 0.3869214297451314 1.7535899646617803 1.1146116282865457 0.9030508481280868 0.2968248594231644 0.1543599557004599 0.0981765691424607 0.1854358412925483 0.0136772183990335 0.0028896459807526 +Carboxypeptidase activity 4 11 1.96859960116998 0.0489990884169941 3.941747572815534 11.944174757281552 0.6619369631013473 0.2217581052142344 1.5253536449314826 0.7722681563953175 1.6063564059694095 0.2594343390807456 0.0153631225051974 0.1114073342812727 7.654983120717976e-05 0.0024740226177806 0.005348590970678 diff --git a/msigdb_gomf/metrics.json b/msigdb_gomf/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..5b3c7a7331c23e63b1d521acaae8bf76f818bd6a --- /dev/null +++ b/msigdb_gomf/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3329, + "annotations_size": 1383, + "title": "Average number of proteins per term", + "value": 17.376717281272597 +} \ No newline at end of file diff --git a/msigdb_gomf/paths.json b/msigdb_gomf/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..9d904f8f29dfff39b0b94bc014f0fa817552a61c --- /dev/null +++ b/msigdb_gomf/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gomf/fragment/C342/C342_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gomf/result.tsv b/msigdb_gomf/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..67a4ec7965e93d59ec0da11cae9247b91a3fa9ee --- /dev/null +++ b/msigdb_gomf/result.tsv @@ -0,0 +1,417 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Endopeptidase activity 0.6012051900827652 3.2025843374932608 0.0013620041253588 0.8481611688443127 0.1892085960009085 62 P28070,Q16740,O75844,Q9BXS4,Q13043,P28074,Q9Y4E8,P42574,P60900,P20618,Q4J6C6,Q96K76,Q99797,P49721,P28072,P48147,Q8TCT8,P67812,Q99436,P42892,P07858,Q96TA2,Q92905,Q9NZ08,Q9BYT8,P78536,P52888,Q5JRX3 28 +Serine hydrolase activity 0.824381832543441 3.115465943263292 0.0018365455479689 0.9213130307688728 0.1892085960009085 17 Q16740,Q9HB40,Q4J6C6,P42785,Q9H3G5,P10619,P48147,Q5JRX3,O75976 9 +Cis trans isomerase activity 0.7078222513509917 2.955939517758117 0.0031171821160895 0.9866707718086656 0.1892085960009085 26 P62942,P26885,Q9Y680,Q02790,Q96AY3,Q9NWM8 6 +Peptidase activity 0.5624354284579771 2.9446067076089766 0.003233654186469 0.9886596719058692 0.1892085960009085 116 P28070,Q16740,Q9UJ14,O75844,Q9BXS4,Q9UIQ6,P42785,P28074,Q9Y4E8,Q96FZ2,P42574,P60900,P20618,Q96FW1,Q92820,Q4J6C6,Q96K76,Q99797,P49721,P28072,P48147,P09960,Q9HD42,Q7Z2K6,Q8TCT8,O95630,Q9HB40,P67812,Q99436,Q969V3,P42892,P07858,Q96TA2,Q9NZ08,Q9H3G5,P10619,Q9BYT8,P78536,P02786,Q9H8M7,P55786,Q86TI2,Q5JRX3,O75976 44 +Amide binding 0.554281607853077 2.8994943044394548 0.003737651355572 0.994365552840532 0.1892085960009085 110 P62942,Q15392,Q9UIQ6,Q8WTV0,P07602,O43731,Q96AY3,Q92973,P24390,P26885,P10321,Q9Y680,P00374,Q13451,P41440,O60925,P21796,P45880,P42892,Q02790,Q9NZ08,P49327,Q9BYT8,Q9UM22,Q03518,P55786 26 +Anion transmembrane transporter activity 0.6311878130886047 2.8608330082948843 0.004225295462948 0.9971372252865034 0.1892085960009085 39 Q9UJS0,P21796,P53985,Q96NB2,P45880,Q6NUK1,Q9H2D1,Q9Y619,Q9UBX3,Q96QD8,P12235,Q02978,Q9H813,P0CG08,P41440,Q96S66,O95563 17 +Ion transmembrane transporter activity 0.5371616259493568 2.829006520684811 0.0046692747592587 0.9984549982833604 0.1892085960009085 95 Q9UBX3,P12235,Q9HD20,Q9NQ11,Q9Y487,P00846,Q96S66,Q70HW3,P53985,Q93050,Q9Y619,O43772,Q9UDW1,P41440,P21796,P45880,Q9H2D1,Q9HC07,O95563,Q7KZN9,P20674,O75964,Q02978,Q96QD8,Q9H813,Q6P4A7,Q00535,P16615 28 +Tetrapyrrole binding 0.7452876740822477 2.707174146474869 0.0067858650807561 0.9999186572104102 0.1892085960009085 17 P53701,P30519,Q8WUJ1,O15173,P09601,O43169 6 +Cytokine receptor binding 0.6666391265908255 2.70461094306036 0.0068384429994574 0.9999243998559472 0.1892085960009085 26 P62942,P14174,P62993,P78536,Q9Y4E8,Q9H2J4,Q9NZ08,P42574 8 +Organic anion transmembrane transporter activity 0.6569669355213128 2.6444240486589905 0.0081830068937873 0.9999883901495789 0.1951223885191023 26 P53985,Q96NB2,Q6NUK1,Q9H2D1,Q9Y619,Q9UBX3,Q96QD8,P12235,Q02978,P41440,O95563 11 +Peptide binding 0.5002422108175409 2.6114957070104796 0.009014711969667 0.999996361290395 0.2022963855326874 76 P10321,Q15392,Q9UIQ6,Q8WTV0,Q03518,P42892,O43731,P55786,Q9NZ08,Q92973,P24390,O60925 12 +Threonine type peptidase activity 0.8557373048011995 2.609443463168119 0.0090689630535261 0.9999966266197832 0.2022963855326874 10 P28070,Q9UJ14,P28074,P49721,P28072 5 +Macrolide binding 0.9406256465117856 2.5850154313922715 0.0097374639180356 0.9999986734223868 0.2023444062325454 7 P62942,P26885,Q9Y680,Q02790,Q96AY3 5 +Fk506 binding 0.9406256465117856 2.5850154313922715 0.0097374639180356 0.9999986734223868 0.2023444062325454 7 P62942,P26885,Q9Y680,Q02790,Q96AY3 5 +Steroid binding 0.6753570904029762 2.5827139039782336 0.0098026574241363 0.9999987888743724 0.2023444062325454 22 P21796,P45880,P38435,O15118,O15173,P30536,Q14108,P04062 8 +Organic acid transmembrane transporter activity 0.6806626944552748 2.5754787340884007 0.0100101428672674 0.9999990935988298 0.2035886409622183 21 P53985,Q9H2D1,Q9Y619,Q9UBX3,Q96QD8,Q02978,P41440,O95563 8 +Metallopeptidase activity 0.5719696971461238 2.5701330078386255 0.0101659475209017 0.9999992709019212 0.2037609481363345 43 Q9HD42,Q7Z2K6,P78536,O75844,P02786,Q9UIQ6,O95630,Q969V3,P42892,P55786,Q96TA2,Q92905,Q99797,Q9NZ08,Q9BYT8,Q5JRX3,O75976,P09960 18 +Threonine type endopeptidase activity 0.8816010698664067 2.559950887729327 0.0104686956440109 0.9999995224147392 0.2068315153666741 8 P49721,P28070,P28074,P28072 4 +Exopeptidase activity 0.6188814581536909 2.5483109328462397 0.0108245944086231 0.9999997096061958 0.2108509023538848 32 Q7Z2K6,O75844,P02786,Q92820,Q9UIQ6,Q9HB40,P42785,Q969V3,P55786,Q9NZ08,Q9H3G5,P10619,O75976,P09960 14 +Isomerase activity 0.5003198144130673 2.5092438059775857 0.0120989944849589 0.9999999511718588 0.2202689718455635 70 P62942,P26885,Q15125,Q9Y680,Q96PZ0,P48449,Q02790,Q96AY3,Q9NWM8 9 +Transferase activity transferring alkyl or aryl other than methyl groups 0.6489910782511634 2.5051942681173616 0.0122384152788681 0.9999999598303158 0.2202689718455635 24 P53609,O15217,P49356,P37268 4 +Transporter activity 0.5397634502787751 2.501329210286787 0.0123728104074025 0.9999999667209388 0.2202689718455635 166 Q9UBX3,P12235,Q9HD20,Q8WTV0,Q9NS69,Q9NQ11,O15118,O75438,O95168,Q9Y487,P00846,Q96S66,Q70HW3,P53985,Q99595,O43676,Q93050,P17900,Q9Y619,Q9H4L5,O43772,Q9UDW1,Q6NT16,P41440,P04062,P21796,P08183,Q9BSK2,P45880,Q8IXU6,Q9H2D1,Q9Y6M9,P30536,Q9HC07,O95563,Q7KZN9,P51991,P20674,O75964,Q02978,P38435,Q96QD8,Q9H813,Q03518,O75306,O14925,O15173,Q6P4A7,Q00535,Q01469 50 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen 0.5987298852657474 2.4392485006168303 0.0147178434308792 0.9999999987573912 0.2384220797586411 33 Q9BU89,Q16850,Q32P28,Q8NB78,P13674,P30519,Q15800,P09601,Q9H6W3,O15460,Q9NVH6 11 +Protein transporter activity 0.719780762333186 2.3743701143651603 0.0175789197585098 0.999999999977732 0.2520392510210754 14 Q9NS69,Q99595,Q9HD20 3 +Cation transmembrane transporter activity 0.4990998695596144 2.3724572520434486 0.0176702077357602 0.9999999999804176 0.2520392510210754 65 Q7KZN9,Q93050,P20674,Q9Y619,Q96QD8,P12235,O75964,Q9HD20,O43772,Q9HC07,Q9UDW1,Q9NQ11,Q9Y487,Q00535,P00846,P16615,Q70HW3 17 +Metalloendopeptidase activity 0.7054364465761654 2.3601168829482777 0.0182691779044801 0.9999999999915758 0.2559564773078776 15 P78536,O75844,P42892,Q96TA2,Q92905,Q99797,Q9BYT8,Q5JRX3 8 +Protein transmembrane transporter activity 0.7978335817992687 2.352500322209689 0.0186476736133278 0.9999999999950578 0.2559564773078776 10 Q9NS69,Q99595 2 +Inorganic molecular entity transmembrane transporter activity 0.475675399154476 2.3231145815578897 0.0201729978500062 0.999999999999425 0.2559564773078776 72 Q9UBX3,P47985,P12235,Q9HD20,Q96ER9,Q9NQ11,P31930,Q9Y487,P00846,Q96S66,Q13423,P51790,Q93050,O95202,Q9UDW1,Q99797,P21281,O43681,P21796,P45880,Q8N4V1,Q9Y277,Q9HC07,P05023,P55011,Q7KZN9,P20674,Q96QD8,Q02978,O75964,Q9H813,P24539,P0CG08,Q00535,P16615 35 +Nadp binding 0.6736590400186401 2.3181604436329737 0.0204406029403705 0.999999999999606 0.2569941260593859 17 P00374,Q14739,O75874,P35270 4 +Secondary active transmembrane transporter activity 0.6571090045049035 2.2947466961377403 0.0217476450170521 0.9999999999999378 0.2598023302843666 18 Q9UBX3,Q96QD8,Q02978,P12235,P41440 5 +Sphingolipid binding 0.9158222116687622 2.2867173783973422 0.0222123246762409 0.9999999999999678 0.2598023302843666 6 P21796,P45880,Q9UM22 3 +Transmembrane transporter binding 0.58033107743473 2.284210178870303 0.0223591816425472 0.9999999999999738 0.2598023302843666 32 P62942,P21796,P42858,Q9Y4C2,P30536,P16615,P0DP25,Q06787,Q9Y639 9 +Macromolecule transmembrane transporter activity 0.7735503178307032 2.2789469142548153 0.0226702211482587 0.9999999999999832 0.2598023302843666 11 Q9NS69,O14925,Q99595 3 +Serine type exopeptidase activity 0.8635636963683637 2.2755599745197954 0.0228723592392765 0.9999999999999872 0.2598023302843666 7 Q9H3G5,P42785,Q9HB40,P10619 4 +Ceramide binding 0.9313774484219604 2.227158314952556 0.0259366949666968 1.0 0.2598023302843666 5 P21796,P45880,Q9UM22 3 +Nucleobase containing compound transmembrane transporter activity 0.7365106281950795 2.212258813181303 0.0269487871845763 1.0 0.2598023302843666 12 Q9BSK2,P12235,Q9H2D1,P41440 4 +Molecular transducer activity 0.5501203363023932 2.211560618622604 0.0269970390376192 1.0 0.2598023302843666 37 Q99720,Q5KU26,P15260,Q99523,Q15629,Q9BUN8,Q8WTV0,P20645,O15118,O15173,P30536,Q9UBG0,P49327,Q14108 14 +Sterol binding 0.6545353751523638 2.211017633540232 0.0270346159843133 1.0 0.2598023302843666 17 P21796,P45880,O15118,P30536,Q14108 5 +Nucleotide transmembrane transporter activity 0.7659374782062326 2.2073051346480383 0.027292748827892 1.0 0.2598023302843666 10 Q9BSK2,Q9H2D1,P41440 3 +Organophosphate ester transmembrane transporter activity 0.7659374782062326 2.2073051346480383 0.027292748827892 1.0 0.2598023302843666 10 Q9BSK2,Q9H2D1,P41440 3 +Cholesterol binding 0.6875067469859748 2.206136721858533 0.0273744282220445 1.0 0.2598023302843666 14 P21796,P45880,O15118,P30536,Q14108 5 +Serine type carboxypeptidase activity 0.9247894103489814 2.201811323892824 0.0276786388565115 1.0 0.2598023302843666 5 Q9H3G5,P42785,Q9HB40,P10619 4 +Signaling receptor regulator activity 0.651639245620779 2.194668287519586 0.0281874011497775 1.0 0.2616320522828348 17 P43490,Q9UMX5 2 +Palmitoyl protein hydrolase activity 0.8863291442724115 2.1717872517021495 0.0298717136971113 1.0 0.2700168630268304 6 P50897,Q9NUJ1,Q8N2K0 3 +Dioxygenase activity 0.5956151199611195 2.1323933170383023 0.0329745263271439 1.0 0.282088471730115 23 O00625,Q32P28,P13674,Q9H6W3,O15460,Q9NVH6 6 +Prenyltransferase activity 0.8226458253081651 2.1063946965499296 0.0351700815970517 1.0 0.2912588194534282 7 P53609,P49356,P37268 3 +Smad binding 0.6894175771353073 2.0924296033777043 0.0364001029384613 1.0 0.2978777654668164 13 P62942 1 +Antiporter activity 0.7459908173682075 2.081241778019373 0.0374117813138015 1.0 0.2999577135298982 9 Q02978,P12235,P41440 3 +Modified amino acid binding 0.5873854079832288 2.080040423048618 0.0375218253367117 1.0 0.2999577135298982 23 P00374,Q8WTV0,P41440 3 +Iron ion binding 0.5604501166761955 2.036088907146299 0.0417414284285366 1.0 0.3080936090015227 27 Q9BU89,Q16850,Q32P28,P13674,Q15800,Q9H6W3,O15460,Q9NVH6 8 +Glycolipid binding 0.735803599428976 2.034264835220888 0.0419249006431605 1.0 0.3080936090015227 9 P50897,Q9UM22 2 +Solute anion antiporter activity 0.8812803449160904 2.0326674657093715 0.0420861303644133 1.0 0.3080936090015227 5 Q02978,P41440 2 +Glutathione transferase activity 0.758439395982978 2.0278208961749313 0.042578530862992 1.0 0.3083042313273191 8 O15217 1 +Nadph binding 0.8788813765004653 2.02325431160115 0.0430469347346733 1.0 0.310072451760694 5 Q14739 1 +Alcohol binding 0.6313086661507176 2.0167031774549957 0.043726498151009 1.0 0.3133354763878005 16 P21796,P45880,O15118,P30536,Q14108 5 +Growth factor receptor binding 0.5867197051015756 2.008451408865862 0.0445953446357392 1.0 0.3176530387776948 21 P62993,P18085,Q9H2J4,Q9NZ08,Q9Y639 5 +Channel regulator activity 0.591389198257203 2.00663642943837 0.0447883894155101 1.0 0.3176530387776948 20 P62942 1 +Fad binding 0.7488698051156564 1.9850063951421268 0.0471437599923778 1.0 0.330963553652074 8 O95831,Q15392,Q15067 3 +Translation repressor activity 0.7168419648633055 1.9786442436679663 0.0478560745924241 1.0 0.3316521741717885 10 P00374,P34897,Q14011,P34896 4 +Carboxypeptidase activity 0.7076265493284424 1.96859960116998 0.0489990884169941 1.0 0.3371429814960346 11 Q9H3G5,P42785,Q9HB40,P10619 4 +Metalloexopeptidase activity 0.5783115849139343 1.955767539828818 0.0504925443480483 1.0 0.3389863535599559 21 Q7Z2K6,O75844,Q9UIQ6,Q969V3,P55786,Q9NZ08,O75976,P09960 8 +Antigen binding 0.8230590784144932 1.9200971264707676 0.0548456322037038 1.0 0.3594858262451301 6 P30153,Q15392,Q03518 3 +Er retention sequence binding 0.9912834385332128 1.916102319709869 0.0553520731077354 1.0 0.3610939486226329 2 O43731 1 +Exogenous protein binding 0.6217142355662415 1.905323916807248 0.0567379784036738 1.0 0.364745843596187 15 O15118,Q14108,Q8WTV0,P35613 4 +Inorganic anion transmembrane transporter activity 0.6114016503135978 1.9037438340871455 0.0569435546016836 1.0 0.364745843596187 16 P21796,P45880,P51790,Q9UBX3,Q02978,Q9H813,P0CG08,Q96S66,P55011,O43681 10 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced flavin or flavoprotein as one donor and incorporation of one atom of oxygen 0.9843703035767944 1.8880400209766384 0.0590205778978827 1.0 0.3713592512116699 2 P30519 1 +Protein methyltransferase activity 0.5389098002023116 1.8717509484063768 0.0612410673233778 1.0 0.3713592512116699 26 O96028,Q9BV86,Q03164,Q6P2P2,P22061,O60725,Q52LJ0 7 +Folic acid transmembrane transporter activity 0.9795611662158096 1.8684945376456268 0.0616931708017074 1.0 0.3713592512116699 2 P41440 1 +Phosphatidylcholine binding 0.6992072250852827 1.863354519439815 0.062412404334039 1.0 0.372486736564935 9 P21796,P45880 2 +Nucleotidase activity 0.763809983212247 1.8572779620525235 0.0632716181218699 1.0 0.372486736564935 7 Q969T7 1 +Monooxygenase activity 0.6978870342930024 1.8571267823565871 0.0632931186498624 1.0 0.372486736564935 9 P09601,P30519,Q15800 3 +Vitamin transmembrane transporter activity 0.9308270676691734 1.8479318355953112 0.0646122043721986 1.0 0.3768219999453724 4 P41440,Q9H2D1,P04062 3 +Cytokine activity 0.8345347980727635 1.8476670320527369 0.0646505260402954 1.0 0.3768219999453724 5 P43490 1 +Mannose binding 0.8043673450869891 1.844435916654708 0.0651196370115285 1.0 0.3768219999453724 6 P49257,O75503 2 +Mhc class ib protein binding 0.9672377517282822 1.8183248616595833 0.0690144950718243 1.0 0.393466643661354 2 Q9NUQ9 1 +Hydrolase activity acting on glycosyl bonds 0.5223190460937838 1.808330803205928 0.0705550304709672 1.0 0.3964378817289438 29 P04062,P17900,Q9BTY2,Q9NUJ1,O60502,O60476,O75503,P06280,Q04446,P54802,P08236 11 +Procollagen proline dioxygenase activity 0.920324046896038 1.8081633612262624 0.0705810791431762 1.0 0.3964378817289438 4 P13674,Q32P28 2 +Dicarboxylic acid transmembrane transporter activity 0.7504126784638885 1.79961104906849 0.071922075203394 1.0 0.3994708032381281 7 Q02978,P41440 2 +N6 methyladenosine containing rna binding 0.7486817601796852 1.7921359270238284 0.0731111951366907 1.0 0.4044511314961732 7 Q7Z739,Q9H6S0,P22626,Q9Y5A9 4 +O acyltransferase activity 0.6767230391564054 1.7871643667814432 0.0739109266745665 1.0 0.4052915030838789 10 Q96N66,O15228,P23786,Q8NCC3 4 +Protein prenyltransferase activity 0.819064160113148 1.7857344575512208 0.0741422633985693 1.0 0.4052915030838789 5 P53609,P49356 2 +Translation repressor activity mrna regulatory element binding 0.7443713587768543 1.7734969126112543 0.0761464030279213 1.0 0.4113690444828717 7 P00374,P34896 2 +Peptide antigen binding 0.8110709987966506 1.7536061914035317 0.0794980094011119 1.0 0.4191442656450759 5 Q15392,P04439,Q03518,P10321 4 +Porin activity 0.9049166997075976 1.7496222942000552 0.0801835101580956 1.0 0.4191442656450759 4 P21796 1 +Wide pore channel activity 0.9049166997075976 1.7496222942000552 0.0801835101580956 1.0 0.4191442656450759 4 P21796 1 +Voltage gated anion channel activity 0.8093157659946945 1.746539563628599 0.0807172385214884 1.0 0.4191442656450759 5 P21796 1 +Thiolester hydrolase activity 0.5740532386350754 1.7445368825817091 0.0810655159012443 1.0 0.4191442656450759 17 P50897,Q8N2K0,Q9NUJ1,Q9UMR5 4 +2 oxoglutarate dependent dioxygenase activity 0.5466258020807774 1.726534409477112 0.084251314423724 1.0 0.4252538972555121 20 Q32P28,P13674,Q9H6W3,O15460,Q9NVH6 5 +Amyloid beta binding 0.5984092711762536 1.7233358384723787 0.0848278103806277 1.0 0.4266067700233021 14 O60925,Q9UHV9,Q8WTV0,Q5SW96,P10909,O00264 6 +Isocitrate dehydrogenase activity 0.8026898677752794 1.7198268020639045 0.0854639291467145 1.0 0.427793710577233 5 P48735 1 +Hydrolase activity hydrolyzing o glycosyl compounds 0.5308687511770991 1.7117605316126123 0.0869408083123479 1.0 0.4318305383115962 23 P04062,P17900,Q9BTY2,Q9NUJ1,O60502,O60476,P06280,Q04446,P54802,P08236 10 +Rna strand annealing activity 0.7987364620938642 1.7038612021229056 0.0884070207946559 1.0 0.4342316684898097 5 Q06787,P23588,Q15056,P51114 4 +Amide transmembrane transporter activity 0.8903283439073081 1.693984479479766 0.0902682323423429 1.0 0.4360800227437332 4 Q9H2D1,P41440 2 +Collagen binding 0.6509981617559836 1.6927908977503117 0.0904952758694515 1.0 0.4360800227437332 11 Q32P28,Q92791,P07858,O75718,Q9UBG0 5 +Lipopolysaccharide binding 0.7251096010961655 1.6897921024666616 0.0910677352547386 1.0 0.4373148536711929 7 P28070,Q8WTV0 2 +Manganese ion transmembrane transporter activity 0.9344755034565646 1.6844404804470752 0.0920965730966554 1.0 0.4376960845109087 2 Q9HD20 1 +Scavenger receptor activity 0.7918183105148618 1.6758749694076396 0.0937626855254114 1.0 0.4438346714987426 5 Q8WTV0 1 +Palmitoyltransferase activity 0.7913583618076935 1.6740122086478884 0.0941281999854874 1.0 0.4438346714987426 5 P23786 1 +Intramolecular transferase activity 0.6463096369137727 1.6695878179469723 0.0950009422847117 1.0 0.4438346714987426 11 Q96PZ0 1 +Cargo receptor activity 0.6793657448843817 1.667864712932331 0.0953425859833143 1.0 0.4438346714987426 8 Q14108,Q8WTV0,P02786 3 +Vitamin d binding 0.9302675082657056 1.6672008060942904 0.0954744825148894 1.0 0.4438346714987426 2 P04062 1 +Carbohydrate derivative transmembrane transporter activity 0.6785564807978317 1.6641106529964167 0.0960903185575352 1.0 0.4438346714987426 8 P12235,P41440 2 +Anion channel activity 0.6488189414680602 1.6516144158650496 0.0986131793729776 1.0 0.4470280419533337 10 P21796,P45880,Q9H813,P0CG08,Q96S66 5 +Pentosyltransferase activity 0.6052384326550931 1.6507372818951664 0.0987922316118812 1.0 0.4470280419533337 13 P43490 1 +Organic cation transmembrane transporter activity 0.9682573919715144 1.6412990003108374 0.1007353635251508 1.0 0.4523279472574145 3 Q70HW3 1 +L amino acid transmembrane transporter activity 0.6719082116700281 1.6332198612802546 0.1024227642418043 1.0 0.4540085991872287 8 Q9Y619 1 +5 3 exodeoxyribonuclease activity 0.9194469492034808 1.6228360532743895 0.1046244563786351 1.0 0.456453069942127 2 Q9UQ84 1 +Phospholipase d activity 0.9194469492034792 1.6228360532743833 0.1046244563786364 1.0 0.456453069942127 2 P09601 1 +Phosphatidylserine binding 0.6357991972089687 1.6173779008393192 0.1057967330209681 1.0 0.4592859727382795 11 Q8WTV0 1 +Sulfur compound transmembrane transporter activity 0.7709062500751147 1.5909284203247531 0.1116256857045858 1.0 0.4764763065723526 5 Q02978,Q70HW3 2 +Proton channel activity 0.6234303562420148 1.555600992735203 0.1198030025208123 1.0 0.4916544584162713 11 P00846 1 +Proton transporting atp synthase activity rotational mechanism 0.6234303562420148 1.555600992735203 0.1198030025208123 1.0 0.4916544584162713 11 P00846 1 +Peptidyl proline dioxygenase activity 0.7594724911088533 1.5442774457763124 0.1225211340511442 1.0 0.4998428566157302 5 P13674,Q32P28 2 +Folic acid binding 0.8482494861028247 1.5325304460699032 0.1253915903856297 1.0 0.5045037793052727 4 P00374 1 +G protein alpha subunit binding 0.7265827455955847 1.523783768706177 0.1275627354975013 1.0 0.5069519057271388 6 P80303 1 +Glycosyltransferase activity 0.4311124793134709 1.5162055429674992 0.1294673869112146 1.0 0.5115811317091709 48 Q16739,P43490,P46976,O43505,Q13126,O43909,O75340,Q06203,P15291,P04062 10 +Active transmembrane transporter activity 0.399257581917914 1.4803582197125982 0.1387776736932138 1.0 0.540646542866802 70 P08183,P53985,O43676,Q7KZN9,P20674,Q9UBX3,Q96QD8,P12235,Q02978,Q9HD20,Q9Y6M9,Q03518,Q9UDW1,Q9NQ11,O75306,O75438,O95168,P41440 18 +Succinate transmembrane transporter activity 0.882476705740898 1.4710454837046023 0.1412788167548577 1.0 0.5457782222680678 2 Q02978 1 +Sulfate transmembrane transporter activity 0.882476705740898 1.4710454837046023 0.1412788167548577 1.0 0.5457782222680678 2 Q02978 1 +Active ion transmembrane transporter activity 0.4517102114124284 1.4673583100301528 0.1422786091958465 1.0 0.5461728997536947 38 Q7KZN9,P51790,O95202,P20674,P47985,Q96QD8,P12235,Q02978,Q9HD20,P55011,Q9UDW1,Q9NQ11,P31930,P41440,P16615,P21281,P05023 17 +Abc type transporter activity 0.671424198038701 1.4532210416745233 0.1461623917555465 1.0 0.5568666330521237 7 Q9NQ11,Q9HD20,Q03518 3 +Procollagen proline 4 dioxygenase activity 0.9142871895742009 1.440750806615942 0.1496550957208284 1.0 0.5624266233203961 3 P13674 1 +Sulfotransferase activity 0.8716561466786799 1.426617432998833 0.153690196500853 1.0 0.5731118331484513 2 Q8NCH0 1 +Quaternary ammonium group binding 0.5605781578640787 1.4080284247360115 0.1591226533050431 1.0 0.5884134479167773 13 P21796,P45880 2 +Mrna 3 utr binding 0.4166200711765692 1.4008296013635568 0.161265034488343 1.0 0.5915902989320383 51 Q5VTR2,Q13148,P51116,Q92804,Q9BWF3,Q92945,P11940,P22626,Q14011,P16989,Q14103,Q96B26,P48643,Q13310,Q06787,Q01085,P51114,P35637 18 +Metalloaminopeptidase activity 0.5757735816126092 1.397600196435929 0.1622331593451096 1.0 0.5920012120693579 12 Q9UIQ6,Q9NZ08 2 +Purine nucleotide transmembrane transporter activity 0.6204894164145849 1.3915041795919272 0.1640725931125821 1.0 0.5963259258501855 8 P41440 1 +Tap binding 0.8108270676691741 1.3880780677163784 0.1651132742863099 1.0 0.5977792103088132 4 P04439,Q03518,P10321 3 +Ganglioside binding 0.8955576547857215 1.3710354625789123 0.1703639014890612 1.0 0.6116515883039942 3 Q9UM22 1 +Glycosphingolipid binding 0.8955576547857215 1.3710354625789123 0.1703639014890612 1.0 0.6116515883039942 3 Q9UM22 1 +C4 dicarboxylate transmembrane transporter activity 0.689443887942315 1.3679420794597388 0.1713302068385016 1.0 0.6116515883039942 6 Q9UBX3,Q02978 2 +Pre mrna intronic binding 0.7163040486227944 1.367085315007064 0.1715985656268617 1.0 0.6116515883039942 5 P22626,Q9BWF3 2 +O methyltransferase activity 0.6132713801166415 1.3572225237737117 0.1747105160634965 1.0 0.61895397240387 8 O60725,Q86VU5,P21964 3 +Interleukin 6 receptor binding 0.8545235948301636 1.3563435679336762 0.1749898793997926 1.0 0.61895397240387 2 Q9NZ08 1 +Voltage gated channel activity 0.5901850181868926 1.3357294369924573 0.1816377240967628 1.0 0.6375760721467589 9 P21796 1 +Scaffold protein binding 0.4891434772293588 1.3330693812589878 0.1825090362869612 1.0 0.6387335568463224 19 P46108,P07602,Q9UQB8 3 +Proton transmembrane transporter activity 0.4428144450176799 1.3289537288122886 0.183863236033543 1.0 0.6387335568463224 35 Q93050,O75964,P12235,Q9UDW1,Q9Y487,P00846 6 +Passive transmembrane transporter activity 0.4436258411064444 1.3149835084922417 0.1885154450144017 1.0 0.6459061328370203 34 P21796,P45880,O75964,Q9H813,Q96ER9,P0CG08,Q00535,Q99797,P00846,Q96S66 10 +Sterol transporter activity 0.6026036016721368 1.3064274205305444 0.1914072460444378 1.0 0.6504084060920332 8 O15118,P30536 2 +Modified amino acid transmembrane transporter activity 0.877594045621291 1.3042155198256562 0.1921601097375198 1.0 0.6513662543308578 3 P41440 1 +Poly pyrimidine tract binding 0.5057679741931008 1.2811923299278942 0.2001261195294548 1.0 0.6589867221648477 16 P31943,P11940,O43347,Q13310,Q06787,P26368 6 +Hexosyltransferase activity 0.4302112098409738 1.2708497890386443 0.2037820920894464 1.0 0.6646948899993029 37 Q16739,Q6ZXV5,P46976,Q10471,O43505,Q13126,P26572,O75340,O43909,Q04446,P15291,P04062 12 +Proline rich region binding 0.6912842348253736 1.263870165906025 0.2062766315929165 1.0 0.669672726509398 5 Q9UQB8 1 +14 3 3 protein binding 0.6905331575633185 1.260768840599032 0.2073921432216914 1.0 0.6717174100131129 5 P31749 1 +Leucine binding 0.8283739104298029 1.2494197191166645 0.2115115997639669 1.0 0.6818660663719494 2 Q8IWV7 1 +Amino acid transmembrane transporter activity 0.5625397982936823 1.246849533652321 0.2124526740860668 1.0 0.6833070889791405 11 Q96QD8,Q96NB2,Q9Y619 3 +Death receptor binding 0.824767057409076 1.23471905666774 0.2169350810312651 1.0 0.6944935580237029 2 P42574 1 +Sequence specific mrna binding 0.5871843670157898 1.2327737798175606 0.2176601764097725 1.0 0.6947782537177649 8 P00374,Q06787 2 +Protein geranylgeranyltransferase activity 0.7700012366309739 1.230204589347773 0.2186205017465456 1.0 0.6947782537177649 4 P53609 1 +Single stranded dna exodeoxyribonuclease activity 0.683102201773917 1.2300815192632577 0.218666579795107 1.0 0.6947782537177649 5 Q9UQ84 1 +Monosaccharide binding 0.442573804034946 1.2243277299023554 0.2208286201987366 1.0 0.6947782537177649 29 Q32P28,P13674,O75503,P49257,P35613 5 +Lysophospholipase activity 0.6202362396799688 1.2241625702664702 0.2208909059725845 1.0 0.6947782537177649 7 Q8NCC3 1 +Atp transmembrane transporter activity 0.6815714220950991 1.2237594830607432 0.2210429729832368 1.0 0.6947782537177649 5 P12235,Q6NUK1,P05141 3 +Mitochondrial ribosome binding 0.7659119398406328 1.21440779017302 0.2245920420939802 1.0 0.7041675786494853 4 Q07021,Q15070 2 +Mannosyltransferase activity 0.7644280538579653 1.2086773225608036 0.2267868372949251 1.0 0.7064103513037869 4 Q6ZXV5,O75340 2 +Mhc protein binding 0.56389145205143 1.205176959992541 0.2281349948312667 1.0 0.7085851080296787 9 Q9NUQ9 1 +Aminopeptidase activity 0.500358757806004 1.2042066116583228 0.2285097311505688 1.0 0.7085851080296787 15 P09960,P55786,Q9UIQ6,Q9NZ08 4 +G protein coupled receptor activity 0.8163510670273375 1.2004755031747578 0.2299547209563988 1.0 0.7114706467174486 2 Q99720 1 +Hexosaminidase activity 0.6738346811222169 1.1918084975921672 0.2333363430620454 1.0 0.7151497812131666 5 P17900,O60502 2 +Ribosome binding 0.405387827743265 1.1905998005585938 0.2338107299637679 1.0 0.7151497812131666 43 Q7Z739,Q8WWC4,Q9NTK5,Q07021,Q15070,Q99543,P46379,Q9BSH4,P41227,Q96A33,Q969V3,Q9BYJ9,Q9BXJ9,P09132,Q06787,Q9BRP8 16 +Cell cell adhesion mediator activity 0.475077535851353 1.188161048448105 0.2347699664204205 1.0 0.7151497812131666 18 P35613,Q9UQB8,Q9Y639 3 +Histone h3 methyl lysine 4 demethylase activity 0.7570328512835887 1.1801346940597364 0.2379466478058627 1.0 0.7200879954387487 4 Q9H6W3 1 +L ascorbic acid binding 0.575060284131304 1.1747072077548215 0.2401118747351744 1.0 0.7209500475584752 8 P13674,Q32P28 2 +Gated channel activity 0.500972121562427 1.1672384146325994 0.2431141015069686 1.0 0.7209500475584752 14 P21796,P45880,Q9H813,Q96ER9,P0CG08,Q00535 6 +Snap receptor activity 0.5166258969637412 1.164732562483949 0.2441272638959613 1.0 0.7209500475584752 13 Q86Y82,Q9P2W9,O15400,O43752,O95721 5 +Signal sequence binding 0.434376095818878 1.162664303436153 0.2449657300216319 1.0 0.7209500475584752 29 O43731 1 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen nad p h as one donor and incorporation of one atom of oxygen 0.8370414912808091 1.15392894333478 0.2485293018611651 1.0 0.7282119162584564 3 Q16850,Q15800 2 +Retinoic acid binding 0.8001202284340205 1.1347065136420822 0.2564983072455691 1.0 0.7436837713220589 2 Q01469 1 +Carboxylic acid binding 0.4154527397714673 1.1282760672121643 0.2592033475851456 1.0 0.7467496488496056 36 Q32P28,P00374,P13674,Q9UM22,Q15067,P34896,P07602,P41440,O15460 9 +Nuclear export signal receptor activity 0.5644039218668451 1.1235937158657112 0.2611854232479378 1.0 0.7478663361322939 8 Q9HAV4 1 +Transition metal ion transmembrane transporter activity 0.8241620231276154 1.1064856655554074 0.2685163650211144 1.0 0.7547929528947179 3 Q9HD20 1 +Protein phosphatase regulator activity 0.4438517716423683 1.094538205696297 0.2737190005750263 1.0 0.7601959670204299 22 P30154,Q86XL3,P30153 3 +Retromer complex binding 0.6498594510690946 1.0928941307739883 0.2744402855356256 1.0 0.7601959670204299 5 Q99523,P20645 2 +Symporter activity 0.590876794405441 1.0919937413145562 0.2748358521404301 1.0 0.7601959670204299 7 Q96QD8,P53985,Q9H2J7,P55011 4 +Pre mrna 3 splice site binding 0.8180998196031183 1.0842227222815122 0.2782660592930006 1.0 0.7626399384635789 3 Q01081,O95391 2 +Lipid transporter activity 0.4574642819601422 1.0753699894613584 0.2822091123420871 1.0 0.7626399384635789 18 P08183,P17900,Q9H4L5,O15118,P30536,Q01469 6 +Epidermal growth factor receptor binding 0.5378253139574135 1.0750849553269817 0.2823366944998933 1.0 0.7626399384635789 9 P18085 1 +Flap endonuclease activity 0.7274613059029202 1.0663992782653875 0.2862431878168814 1.0 0.7654696868119018 4 Q9UQ84 1 +Beta n acetylhexosaminidase activity 0.7253485608771888 1.05830666960217 0.2899156532329137 1.0 0.7660935280975124 4 O60502 1 +Poly g binding 0.6155478688341323 1.055334044470647 0.2912725760504373 1.0 0.7660935280975124 6 O14979 1 +5 3 exonuclease activity 0.5295413363786605 1.0336787020084734 0.3012863929791822 1.0 0.7779377523491283 9 Q9UQ84 1 +Oxidoreductase activity acting on diphenols and related substances as donors 0.7165404914646016 1.0246305386536116 0.3055375493185472 1.0 0.7823851229463811 4 P47985,Q9UDW1 2 +Ubiquinol cytochrome c reductase activity 0.7165404914646016 1.0246305386536116 0.3055375493185472 1.0 0.7823851229463811 4 P47985,Q9UDW1 2 +Cell adhesion mediator activity 0.4386357171253252 1.0191890155678551 0.3081132404699498 1.0 0.7847525074952865 20 Q9Y639,Q9UQB8,P35613 3 +Protein arginine n methyltransferase activity 0.6055282786160614 1.0129844994942143 0.311067564812503 1.0 0.7891159118384818 6 Q99873,Q86X55,Q6P2P2 3 +Nedd8 specific protease activity 0.7952495490078016 1.000791256960735 0.3169277373176236 1.0 0.7894578993669528 3 Q96FW1,Q92905 2 +Demethylase activity 0.4871125134809905 0.9999035003550728 0.317357210294187 1.0 0.7894578993669528 13 Q16850,Q9H6W3,Q8NB78 3 +C palmitoyltransferase activity 0.7661556958220426 0.9986631880808234 0.317957878977724 1.0 0.7894578993669528 2 O15270 1 +Cyclin dependent protein serine threonine kinase inhibitor activity 0.7919422730005969 0.988789176177582 0.3227663010527055 1.0 0.7894578993669528 3 O94992,P42574 2 +Acyltransferase activity 0.3717278163272248 0.9789163667295556 0.3276213046244618 1.0 0.7894578993669528 52 Q9UJ14,Q96G23,P23786,Q9BWD1,Q8NCC3,P49327,Q86UY6,O15270 8 +Solute proton antiporter activity 0.7586414186955212 0.9689405018229788 0.3325748759822011 1.0 0.7894578993669528 2 P51790 1 +Isoprenoid binding 0.7856283824413638 0.9659353583158716 0.3340765280370372 1.0 0.7894578993669528 3 Q01469,P11717 2 +Phosphatase regulator activity 0.4154475069062969 0.9644143029914222 0.3348382541652024 1.0 0.7894578993669528 25 P30154,Q86XL3,P30153 3 +Transcription elongation regulator activity 0.7559362789299632 0.958280066302386 0.3379215526949228 1.0 0.7894578993669528 2 O14776 1 +Metal ion transmembrane transporter activity 0.4265621388754603 0.9560514942728856 0.3390462191410672 1.0 0.7894578993669528 21 Q8N4V1,O95202,Q96QD8,Q9HD20,Q96ER9,P05023,Q00535,P16615,Q9HC07,P55011 10 +Small ribosomal subunit rrna binding 0.5883904450933091 0.9407583226536242 0.3468287233320115 1.0 0.792366559545593 6 Q9NVS2,Q14011 2 +Acetylglucosaminyltransferase activity 0.5569451498660927 0.9394371900007128 0.3475063262578106 1.0 0.792366559545593 7 O43505 1 +Endodeoxyribonuclease activity producing 5 phosphomonoesters 0.5873647568043624 0.9364466824320042 0.349043252066374 1.0 0.7939585815917685 6 Q9UQ84 1 +Sphingolipid transporter activity 0.7487225728884785 0.929962204714438 0.3523906537628156 1.0 0.7971194636918394 2 P08183 1 +Neutral amino acid transmembrane transporter activity 0.6096785590785825 0.9281790480310488 0.3533147008265347 1.0 0.7971194636918394 5 Q96QD8 1 +Mirna binding 0.4582774916780366 0.918067610072087 0.3585834707883375 1.0 0.798966088894816 14 P22626,P98175,P67809,P09651,Q06787 5 +Atpase coupled transmembrane transporter activity 0.4247967895778695 0.9106924351657846 0.3624574510931981 1.0 0.798966088894816 19 Q9NQ11,Q9HD20,Q03518,P08183 4 +Rna 7 methylguanosine cap binding 0.5177180547932371 0.8997203084225467 0.3682691130333488 1.0 0.798966088894816 8 Q7L576,Q96F07,P06730 3 +Nucleobase transmembrane transporter activity 0.7409077246768649 0.8994774051604686 0.3683984256504342 1.0 0.798966088894816 2 P12235 1 +Oxidative phosphorylation uncoupler activity 0.7409077246768649 0.8994774051604686 0.3683984256504342 1.0 0.798966088894816 2 P12235 1 +Sulfuric ester hydrolase activity 0.7403065825067593 0.8971412128138337 0.3696435696653961 1.0 0.798966088894816 2 O43681 1 +Pre mrna binding 0.4203443831301207 0.8967486382642494 0.3698530605023695 1.0 0.798966088894816 20 Q01081,Q9BWF3,O95391,P22626,P62995,P09651,Q13247,P26368 8 +Omega peptidase activity 0.4011788630813481 0.8928478660939444 0.3719386490466401 1.0 0.799986238929243 27 Q9UJ14,Q92820,Q96FW1,Q9H8M7,Q9Y4E8,Q96K76 6 +Adp transmembrane transporter activity 0.6808036142794932 0.8893387983456199 0.3738210259371708 1.0 0.8022808069643896 4 P12235,P05141 2 +Ubiquitin like protein binding 0.3854211122304848 0.8808021719266796 0.3784249039957039 1.0 0.8042353355004346 36 Q92783,O95071,Q96FW1,Q8IZL8,Q9BTE7,P54725,O94888 7 +Cation channel activity 0.417101687829377 0.8750454635662857 0.3815491690161492 1.0 0.8042353355004346 20 P00846 1 +Serine transmembrane transporter activity 0.6745564789340878 0.8659716595574639 0.3865057035821642 1.0 0.8060052603482948 4 Q96QD8 1 +Nitric oxide synthase regulator activity 0.5933870573546854 0.8621240763973287 0.3886192437210853 1.0 0.8060052603482948 5 P31749 1 +Nad binding 0.3941660001481294 0.8577383381788761 0.3910369652034424 1.0 0.8060052603482948 29 Q16836,O75874,P48735 3 +Oxidoreductase activity acting on a sulfur group of donors 0.3940539652896565 0.8568860231220963 0.3915078779357932 1.0 0.8060052603482948 29 P78417,O43396,Q6DKJ4,Q9UHG3,Q8N4Q1,P30048,O95881 7 +Phosphoric diester hydrolase activity 0.4898056460530327 0.8533492450743657 0.3934656587221286 1.0 0.8060052603482948 10 P09601 1 +Anaphase promoting complex binding 0.753173915486703 0.8499162864127441 0.3953716301253036 1.0 0.8060052603482948 3 Q16763 1 +Phosphatidylinositol 3 phosphate binding 0.5071478768511373 0.8492940430789122 0.3957176947046219 1.0 0.8060052603482948 8 Q9UMY4 1 +Phosphoric ester hydrolase activity 0.3416290530678328 0.8316042032067504 0.4056323888168791 1.0 0.8161566906265317 69 Q969T7,Q9NPH0,Q8IV08,Q9H0P0,P30153,P09601 6 +Organic acid sodium symporter activity 0.722572888488107 0.8288431942090718 0.4071931428288553 1.0 0.8161566906265317 2 Q96QD8 1 +Amino acid sodium symporter activity 0.722572888488107 0.8288431942090718 0.4071931428288553 1.0 0.8161566906265317 2 Q96QD8 1 +Vitamin binding 0.3566466555666533 0.8223206247981149 0.4108944413805924 1.0 0.8172856752350115 48 Q32P28,P00374,P13674,P38435,P34896,P41440,O15460,O95470,O15270,P04062 10 +Phospholipid binding 0.3590080551112598 0.8202177201485565 0.4120920019345941 1.0 0.8172856752350115 107 P50897,Q13576,Q8WTV0,Q9NQ11,P07602,P53365,Q9UMY4,Q14108,Q96L92,Q92783,P30086,P21796,P45880,P31749,Q9Y2I1,Q8NCC3,O60313,Q9UM22,P04083 19 +Udp glycosyltransferase activity 0.4086394229173199 0.8184568191821544 0.4130963889444241 1.0 0.8172856752350115 20 Q16739,P46976,O43505,P26572,O43909,P15291 6 +Quinone binding 0.5817167494629552 0.8151921810085966 0.4149623128169355 1.0 0.8172856752350115 5 O75306,Q8N0U8 2 +Hexokinase activity 0.7171626089570039 0.8082651094792781 0.4189379833195228 1.0 0.8172856752350115 2 P52789 1 +Sodium ion transmembrane transporter activity 0.5554615299090495 0.8032630987420398 0.4218226817519488 1.0 0.8172856752350115 6 Q96QD8,P55011,P05023 3 +Endodeoxyribonuclease activity 0.4798307511704742 0.8030614076813147 0.4219392423122186 1.0 0.8172856752350115 10 Q9UQ84 1 +Ubiquitin conjugating enzyme binding 0.495244040676703 0.792758830829396 0.4279183467966112 1.0 0.8213406076074363 8 Q9UBS8,Q9BTE7 2 +Hsp70 protein binding 0.4252994221495521 0.7902571126642938 0.4293776278381609 1.0 0.8213406076074363 16 P46379,Q99543 2 +Peroxisome targeting sequence binding 0.7324113048707178 0.7772788682192154 0.4369942597095089 1.0 0.8347556093622249 3 Q9NXR7,P50542 2 +Nitric oxide synthase binding 0.7081454764051622 0.77426634526704 0.4387733014047525 1.0 0.8351496907654257 2 P0DP25 1 +Hormone binding 0.4767202145369875 0.7707274798122671 0.4408684801711726 1.0 0.8351496907654257 9 P42892 1 +1 phosphatidylinositol 4 kinase activity 0.73024476739682 0.7697846638321362 0.4414276384306046 1.0 0.8351496907654257 3 P42356 1 +Solute cation symporter activity 0.5689526702381996 0.7643158291200096 0.444679054630686 1.0 0.8401518204292879 5 Q96QD8,Q9H2J7,P55011 3 +Magnesium ion binding 0.334339746846758 0.7560969432434309 0.4495910745511857 1.0 0.8443503457923348 82 Q969T7,Q9H773,O75874,Q9H0P0,P48735,Q9BQG2 6 +Translation initiation factor binding 0.4128966800481546 0.7501226375502202 0.4531808466367224 1.0 0.8456709389648146 17 P55010,P06730 2 +Death domain binding 0.642806733840189 0.7489916253230784 0.4538622530821841 1.0 0.8456709389648146 4 Q13546,P63244 2 +Solute sodium symporter activity 0.7227901383042565 0.7441339532735579 0.4567954400491909 1.0 0.8479840182389679 3 Q96QD8,P55011 2 +Tumor necrosis factor receptor superfamily binding 0.5625590637460898 0.7390374881189179 0.4598842338599764 1.0 0.8502939778453843 5 Q13546,P42574 2 +Dna translocase activity 0.6979260595130696 0.7362206907328148 0.4615964024027275 1.0 0.851727908433345 2 Q2NKX8 1 +Syntaxin binding 0.3973586196158275 0.7301456372575695 0.46530116785844 1.0 0.8557333978034874 19 O43752,O95721,Q9P253 3 +Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters 0.4141243131590992 0.7223845499799849 0.4700580831289707 1.0 0.8558287533619242 16 Q9BQG2,Q9UQ84 2 +Xenobiotic transmembrane transporter activity 0.7164067710517732 0.7223443098332815 0.4700828168771478 1.0 0.8558287533619242 3 P41440 1 +Structural constituent of postsynapse 0.635409738446265 0.7222447176696957 0.4701440346435144 1.0 0.8558287533619242 4 P07196 1 +Single stranded rna binding 0.3528892773619448 0.719934609257207 0.4715652577514488 1.0 0.8558723772575509 43 P31943,O00571,Q93062,P11940,Q15056,P52597,O14979,O43347,P09651,P23588,Q13310,Q06787,P51114,P26368 14 +Lipase activator activity 0.7140709561034192 0.7144132945972297 0.4749716535670947 1.0 0.8580208310380192 3 Q9Y263,P42574 2 +Volume sensitive anion channel activity 0.6904117823865292 0.7086030098765047 0.4785708679778662 1.0 0.8580208310380192 2 P51790 1 +Flavin adenine dinucleotide binding 0.3823475536911264 0.7052903360156562 0.4806295732893844 1.0 0.85988523020602 24 O95831,Q15392,Q15067,Q16134,Q8NB78 5 +Cyclin dependent protein serine threonine kinase regulator activity 0.5025778115789594 0.6986638366931759 0.4847621390496641 1.0 0.860789595864887 7 O94992,P11802,P42574,P42771 4 +Phosphatidylinositol kinase activity 0.5479060781854905 0.6817052085530638 0.4954253733066112 1.0 0.8679750742661774 5 P42356 1 +Copper ion binding 0.4413853974138121 0.6811028062138968 0.495806441554794 1.0 0.8679750742661774 12 Q9NQ11,O60888 2 +Galactosyltransferase activity 0.5454261021030649 0.6720931154515558 0.5015244190754404 1.0 0.8683582666128142 5 O43505 1 +Lipid kinase activity 0.6795912233243011 0.669410599809264 0.5032335918260855 1.0 0.8683582666128142 2 Q9NRA0 1 +Intramolecular oxidoreductase activity transposing c c bonds 0.4957154825509132 0.668899026254751 0.5035598914124924 1.0 0.8683582666128142 7 P14174,Q15125 2 +Carbohydrate binding 0.3401761777302365 0.666089901286958 0.5053536390275828 1.0 0.8703662301060362 48 P35613,Q5KU26,Q32P28,Q12907,P13674,Q14165,O75503,P52789,Q9UBG0,P11717,Q04446,P49257,O15460,P08236 14 +Ubiquitin specific protease binding 0.4665763389934257 0.6582750949344827 0.5103613783124805 1.0 0.8736765682816122 8 P46379,P54725 2 +Ubiquitin protein transferase activator activity 0.675082657048393 0.6532945424366731 0.5135664101444 1.0 0.8754431192182383 2 P68036 1 +Phosphatase activity 0.3339787214175093 0.6364914501220816 0.5244561519042614 1.0 0.8801019740607601 58 Q969T7,Q9NPH0,P30153 3 +Protease binding 0.3668834265160471 0.6336479222641654 0.5263106186348121 1.0 0.8801019740607601 26 P14174,P46379,P04080,Q9BUN8,P54725,P07602,P41440 7 +Peptidase activator activity involved in apoptotic process 0.6897245852649925 0.6332304308578408 0.5265831762458011 1.0 0.8801019740607601 3 Q9BXK5 1 +Fatty acid binding 0.4564959659625992 0.6117653230704473 0.5406930357480015 1.0 0.8951827662218326 8 Q15067 1 +Peptidyl proline 4 dioxygenase activity 0.6034821507082833 0.6096023308404307 0.5421252672395782 1.0 0.8951843699884685 4 P13674 1 +Hydrolase activity acting on ether bonds 0.5072901805678884 0.6077955215779767 0.5433230999168759 1.0 0.8951843699884685 6 P07099 1 +Gtpase inhibitor activity 0.5047094433271784 0.5976054035366423 0.550103257878144 1.0 0.8951843699884685 6 O43924 1 +Potassium ion transmembrane transporter activity 0.5957610308571847 0.583154169280854 0.559789520519065 1.0 0.8951843699884685 4 P55011,Q96ER9 2 +Glucosyltransferase activity 0.4333182051927012 0.5725672613343812 0.5669377319216113 1.0 0.8951843699884685 10 Q16739,P04062 2 +Epoxide hydrolase activity 0.5899368695745901 0.5634367745934183 0.573137501668062 1.0 0.8951843699884685 4 P07099 1 +Ether hydrolase activity 0.5899368695745901 0.5634367745934183 0.573137501668062 1.0 0.8951843699884685 4 P07099 1 +Signaling receptor complex adaptor activity 0.4707643206691586 0.5625335672524362 0.5737525400117658 1.0 0.8951843699884685 7 P46108,P37198,Q5SW96 3 +Structural constituent of muscle 0.470610138165993 0.5618868004655224 0.5741931474280861 1.0 0.8951843699884685 7 P67936,P09493 2 +Heparin binding 0.4276714163050477 0.5584256017022173 0.5765537946132844 1.0 0.8951843699884685 11 Q53GQ0,O14737,P10586,P51858 4 +Ubiquitin binding 0.3500279223133226 0.5451648161502745 0.5856401674454705 1.0 0.9025036240224238 32 Q92783,O95071,Q96FW1,P54725,O94888 5 +Monocarboxylic acid transmembrane transporter activity 0.511287307111121 0.5430504786619189 0.5870950475129844 1.0 0.9025036240224238 5 O95563 1 +Protein demethylase activity 0.4294036667292025 0.5414866561832422 0.58817219260396 1.0 0.9028214676706734 9 Q9H6W3,Q8NB78 2 +Intramembrane lipid transporter activity 0.6581740289782825 0.5327305144594597 0.5942201398941074 1.0 0.9055652329087734 3 P08183 1 +Organic acid binding 0.34677184125965 0.5286568030833924 0.5970435481056544 1.0 0.90566946278482 33 Q32P28,P00374,Q8IWV7,P13674,P34896,P41440,O15460 7 +Catalytic activity acting on a glycoprotein 0.6532799404820238 0.5176924973447767 0.604672833746053 1.0 0.9060467630079628 3 O43505 1 +2 acylglycerol 3 phosphate o acyltransferase activity 0.6515333734215166 0.5123649065113812 0.6083956469915806 1.0 0.906509831566416 3 Q96N66,Q92604 2 +Lysophospholipid acyltransferase activity 0.6515333734215166 0.5123649065113812 0.6083956469915806 1.0 0.906509831566416 3 Q96N66,Q92604 2 +Disulfide oxidoreductase activity 0.3519877882165348 0.5084538530306224 0.6111350940011193 1.0 0.9078408539243266 25 P78417,O43396,Q6DKJ4,Q8N4Q1,O95881 5 +Mhc class ii protein complex binding 0.454846478025282 0.496572346136935 0.6194906582310791 1.0 0.9111877127160916 7 P50995,P07900,P62258,P11142,P08238,P14618 6 +Regulatory rna binding 0.3714457052281577 0.4961356264049866 0.6197987250318917 1.0 0.9111877127160916 17 P22626,P98175,P67809,P09651,Q06787 5 +Calcium ion binding 0.3182035088193147 0.4927907607156543 0.622160439702047 1.0 0.9111877127160916 90 Q9UJS0,P20073,Q96D71,O43852,Q96AY3,Q14257,Q14574,P67936,Q9Y680,Q0IIM8,P80303,Q9NWM8,P0DP25,Q6NUK1,Q02818,O75071,O75340,Q66K14,Q9UM22,Q96A33,P04083,P16615,O60476 23 +Protein arginine omega n monomethyltransferase activity 0.6437269055931036 0.4888118428523202 0.6249749128249764 1.0 0.9117513759883358 3 Q6P2P2 1 +C acyltransferase activity 0.4128147940486599 0.4860346875714203 0.6269425724052278 1.0 0.9136581429256376 11 Q9BWD1 1 +Dynactin binding 0.4750737069616833 0.4834243741330222 0.6287944450667473 1.0 0.9144297765797176 6 P42858,Q9Y5X3 2 +Glucosidase activity 0.4937798393059964 0.4797390852327037 0.6314129320223474 1.0 0.9157432980388396 5 Q13724,P04062 2 +Protein self association 0.3917672293986541 0.4763572005486751 0.6338199206140875 1.0 0.9169173119343964 13 P46108,Q9Y282 2 +Histone arginine n methyltransferase activity 0.6378824931141756 0.4714649368902471 0.6373087530538197 1.0 0.9173284812496172 3 Q86X55 1 +Ribosomal large subunit binding 0.4119794153448898 0.4705562561721578 0.6379576519475658 1.0 0.9173284812496172 10 Q9NTK5 1 +Phosphatidylinositol 4 phosphate binding 0.4197528426378153 0.4474030385770894 0.6545840822834723 1.0 0.9299356928892488 8 P53365,Q9Y5X3 2 +Hydroxymethyl formyl and related transferase activity 0.5536567580838319 0.4457762459850303 0.6557588820788125 1.0 0.9299356928892488 4 P34896 1 +Poly purine tract binding 0.3625768915932447 0.4433895346478107 0.6574840042857564 1.0 0.9299356928892488 17 Q93062,O00571,P11940,O14979,Q13310,Q06787 6 +Udp glucosyltransferase activity 0.4639779263554405 0.4422452162650881 0.6583117693946974 1.0 0.9299356928892488 6 Q16739 1 +Tpr domain binding 0.4819494584837436 0.4382991953126928 0.661169409179609 1.0 0.9299356928892488 5 P08238,P07900,Q9UNE7,O76094 4 +Bh domain binding 0.6249271852039296 0.433934730654689 0.6643358384487186 1.0 0.9299356928892488 3 P63244 1 +Bh3 domain binding 0.6249271852039296 0.433934730654689 0.6643358384487186 1.0 0.9299356928892488 3 P63244 1 +Primary active transmembrane transporter activity 0.3153779245665744 0.4324111826858716 0.6654425919635862 1.0 0.9305430785496864 52 P08183,Q7KZN9,O43676,P20674,Q9HD20,Q9Y6M9,Q03518,Q9UDW1,Q9NQ11,O75306,O75438,O95168 12 +Lipid binding 0.3561983023409828 0.4201369132114223 0.6743854380014249 1.0 0.9351918800851312 160 P50897,P28070,Q13576,P25786,Q8WTV0,Q15067,Q9NQ11,P07602,P53365,O15118,A6NIH7,Q9UMY4,Q14108,Q96L92,Q92783,Q9H4L5,P30086,P04062,P21796,P45880,P31749,Q9Y2I1,P30536,Q8NCC3,O60313,Q9NQZ5,P38435,Q9UM22,Q5T8D3,O15173,P04083,Q01469 32 +Endoribonuclease activity producing 5 phosphomonoesters 0.3705325555090744 0.4183127463224039 0.6757184715222233 1.0 0.9351918800851312 14 Q9UQ84 1 +Nadplus binding 0.4760805380669811 0.4181857012820453 0.6758113492722218 1.0 0.9351918800851312 5 Q16836 1 +Lipid transfer activity 0.4570259256777614 0.4169548538562915 0.6767114298606829 1.0 0.9351918800851312 6 P61916,P30536 2 +Protein arginine omega n asymmetric methyltransferase activity 0.6154188987666981 0.4072444280652739 0.6838284737904337 1.0 0.9400942139683596 3 Q86X55 1 +Atpase coupled cation transmembrane transporter activity 0.3781562692972466 0.4057163282561789 0.6849510434833306 1.0 0.9407023765019328 13 Q9NQ11,Q9HD20 2 +Mrna 5 utr binding 0.3408393684393259 0.3936913615230195 0.6938089198898312 1.0 0.9462896806781426 22 P34896,P34897,P48643,Q06787,P82912,O60506 6 +Deoxyribonuclease activity 0.3472243841365322 0.3798378415883533 0.704065790306986 1.0 0.9518308778050456 18 Q9UQ84,P51530 2 +Proteasome binding 0.3725352369289465 0.3771012157459216 0.7060983877528244 1.0 0.9518633545518388 13 P46379,P54725 2 +Amino acid binding 0.3810716507101785 0.3750544458972332 0.7076199750994832 1.0 0.9518633545518388 12 Q8IWV7,P34896 2 +Exodeoxyribonuclease activity 0.3912181167327924 0.3748742891033393 0.7077539613325889 1.0 0.9518633545518388 10 Q9UQ84 1 +Proteoglycan binding 0.4629203082662955 0.3742485958556922 0.7082193722587433 1.0 0.9518633545518388 5 P07858 1 +Solute cation antiporter activity 0.6022242006311975 0.3714829867387362 0.7102778254649584 1.0 0.9527781111717144 3 P51790 1 +Poly a binding 0.3703945987582383 0.3662991091542735 0.7141418942668647 1.0 0.9561067180746116 13 Q93062,O00571,P11940,O14979,Q13310 5 +Transferase activity transferring sulphur containing groups 0.3877006319064635 0.3514674579426417 0.7252376819596991 1.0 0.961172702599253 9 Q8NCH0,Q5VV42,Q7LGA3,O75648 4 +Vitamin b6 binding 0.3336432546353708 0.3390898994598887 0.7345420072319304 1.0 0.9702689551115184 21 O95470,O15270,P34896 3 +Structural constituent of eye lens 0.588441440079616 0.3358098326186183 0.7370142749766408 1.0 0.9716784959892224 3 P08670 1 +Pdz domain binding 0.3476540772429128 0.334089266041994 0.7383121996440276 1.0 0.9724032151797228 16 P51790,P78536,Q9UQB8,Q15067,Q9BXI6 5 +Class i dna apurinic or apyrimidinic site endonuclease activity 0.5728884881274502 0.3332173867900494 0.7389701946159715 1.0 0.9724032151797228 2 P23396 1 +Phosphatidylinositol 3 5 bisphosphate binding 0.381414478299205 0.3243247344661085 0.7456921954781752 1.0 0.9775282524609634 9 Q9NQ11,Q9Y5X3,Q5MNZ6,Q92538 4 +Misfolded protein binding 0.3487097028768794 0.3202042895402937 0.7488134716723702 1.0 0.9797625651115308 15 P10909,Q9BUN8,P46379 3 +Lys48 specific deubiquitinase activity 0.4412902840374951 0.3059083241339083 0.7596744478591675 1.0 0.9865068182058484 5 Q9H8M7 1 +P type transmembrane transporter activity 0.5004648395943743 0.2934463043301819 0.7691810366439669 1.0 0.9936224510560858 4 P16615,P05023 2 +Cadherin binding involved in cell cell adhesion 0.3682757576731712 0.2809796267260698 0.7787260261247717 1.0 0.997201939009777 11 P04083,Q9UQB8 2 +Importin alpha family protein binding 0.4308062575210631 0.2747032595825801 0.7835442266902262 1.0 1.0 5 Q9ULW0,Q08211,P62826,Q08379 4 +Ubiquitin like protein conjugating enzyme binding 0.357561515354984 0.2652153164781897 0.790843596426229 1.0 1.0 12 Q9UBS8,O14776,Q9UBW7,Q9BTE7 4 +Nadh dehydrogenase activity 0.317347765203965 0.2616462166597404 0.7935942091110184 1.0 1.0 24 O43676,O95831,O75306,O75438,O95168 5 +Translation activator activity 0.4854135338345898 0.2556548011087838 0.7982173989679451 1.0 1.0 4 Q7Z478,P11940,Q9H074 3 +Gamma catenin binding 0.4230877155575216 0.2525968124430441 0.8005797934627783 1.0 1.0 5 Q14574,Q9UJX6 2 +Isopeptidase activity 0.3637087430223065 0.2505899602657306 0.8021311446543449 1.0 1.0 9 O95630 1 +Phosphatase inhibitor activity 0.3861319454831509 0.2379185439354924 0.8119442724544272 1.0 1.0 7 Q12972,Q01105,Q9Y570 3 +G rich strand telomeric dna binding 0.4025324504324288 0.2355991577434494 0.8137437270874213 1.0 1.0 6 P22626 1 +Ccr5 chemokine receptor binding 0.5287045386233852 0.2300797963908006 0.818029763927395 1.0 1.0 2 P42224 1 +Mhc class i protein binding 0.3656263019348543 0.2284553177585776 0.8192922888964083 1.0 1.0 8 Q03518 1 +Structural constituent of synapse 0.380369964925493 0.2187797138029129 0.8268216501123855 1.0 1.0 7 P07196 1 +Oxidoreductase activity 0.3625984605362805 0.2169616261684307 0.8282382504889005 1.0 1.0 234 Q9BU89,O75151,Q8N4Q0,Q16836,P30519,Q15392,Q96CU9,P51648,Q15067,Q06136,O75438,O95168,P48735,Q9H6W3,Q14739,Q9BY49,O43676,O00625,Q32P28,P00374,Q15800,Q9UDW1,Q8N4Q1,P09601,O95881,P14406,Q7LG56,O43169,Q16850,P78417,Q6DKJ4,P13674,O75874,P35270,Q9NZ01,P49327,Q8NBX0,P20674,O95831,Q9UBM7,O75306,Q9UHG3,Q8N0U8,Q3SXM5,Q8NB78,O15460,Q9NVH6 47 +Double stranded rna adenosine deaminase activity 0.520889690411794 0.2144799743041153 0.8301727818057518 1.0 1.0 2 P55265 1 +Rage receptor binding 0.5336740829825566 0.2129917806653917 0.831333373676183 1.0 1.0 3 P26583,Q99584 2 +Nadp retinol dehydrogenase activity 0.3939211555823104 0.2102022475284491 0.8335098254777926 1.0 1.0 6 Q9Y394,Q9BTZ2,Q9HBH5,Q8TC12,Q8NBN7 5 +Atpase binding 0.3052642905616717 0.2092336849323737 0.8342658175654385 1.0 1.0 32 P11233,Q16740,Q93050,Q9Y487 4 +Calcium cation antiporter activity 0.5166816952209283 0.2064183282553106 0.8364641552268537 1.0 1.0 2 O95202 1 +Cation cation antiporter activity 0.5166816952209283 0.2064183282553106 0.8364641552268537 1.0 1.0 2 O95202 1 +Ubiquitin like protein specific protease activity 0.3034336996394069 0.1962061977487729 0.8444487772409355 1.0 1.0 32 Q96FW1,Q9H8M7,O95630,Q9Y4E8,Q96K76,Q92905 6 +N acyltransferase activity 0.3072636494264394 0.1746740867402753 0.8613357304923894 1.0 1.0 19 Q86UY6,Q96G23 2 +Beta tubulin binding 0.3106344751104842 0.1731898595195793 0.8625021941295661 1.0 1.0 18 P42858,Q9UBK9,O14737,P48643 4 +Hyaluronic acid binding 0.4941388638413092 0.1672748916585092 0.8671537593286729 1.0 1.0 2 Q07021 1 +Protein carrier chaperone 0.3407193897431469 0.1670647139512311 0.8673191299545042 1.0 1.0 11 O95817,Q15070,Q8N4V1,P10909 4 +Rna cap binding 0.3347808819210842 0.1666953483674209 0.8676097657917348 1.0 1.0 12 Q7L576,Q96F07,P06730 3 +Extracellular matrix structural constituent 0.5077869653063547 0.1664044884846754 0.8678386419022135 1.0 1.0 3 P11047 1 +Sodium channel regulator activity 0.5048105832832137 0.1615396497551947 0.871668385418759 1.0 1.0 3 Q04917,Q9HD47 2 +Dna clamp loader activity 0.3444093436270639 0.1536611359587775 0.8778769297729507 1.0 1.0 8 P41440 1 +L aspartate transmembrane transporter activity 0.4372932330827105 0.1531604512104019 0.8782717449936015 1.0 1.0 4 Q9UJS0,Q15758,O75746 3 +Acidic amino acid transmembrane transporter activity 0.4372932330827105 0.1531604512104019 0.8782717449936015 1.0 1.0 4 Q9UJS0,Q15758,O75746 3 +Lipase binding 0.4812143071836616 0.1478842722392375 0.8824341006562235 1.0 1.0 2 P30533 1 +Leukotriene c4 synthase activity 0.4806131650135326 0.1470356884584743 0.8831038511292864 1.0 1.0 2 O14880 1 +Metallocarboxypeptidase activity 0.4220104304057677 0.1267921239198125 0.8991049296273483 1.0 1.0 4 O75976 1 +Thiol oxidase activity 0.4810583283223081 0.1263494573780096 0.8994553085889243 1.0 1.0 3 Q6ZRP7,P07237 2 +Phospholipid transporter activity 0.3602437277337998 0.1211916792035583 0.9035392145731382 1.0 1.0 6 P08183,Q7Z3C6 2 +Tumor necrosis factor receptor binding 0.476849067949488 0.1207806009944495 0.903864815767909 1.0 1.0 3 P42224,Q9NXR7 2 +Molecular carrier activity 0.2911491959470201 0.1195453213120313 0.904843336234586 1.0 1.0 35 O95817,Q9HAV4,Q8N4V1,Q15070,Q8TEX9,Q9UI26,O15504,P10909,O00629,Q92973,O75880 11 +Phosphorus oxygen lyase activity 0.4562669071235282 0.1165312138902562 0.9072315494990946 1.0 1.0 2 Q3LXA3 1 +P type potassium transmembrane transporter activity 0.4541629095280985 0.1142389496363336 0.9090483766554012 1.0 1.0 2 P05023 1 +Lys63 specific deubiquitinase activity 0.4714371617558469 0.1139111304300665 0.9093082421949256 1.0 1.0 3 O00487,O95630 2 +Long chain fatty acyl coa binding 0.4529606251878679 0.1129528054679431 0.9100679714551412 1.0 1.0 2 O00154 1 +Cyclin dependent protein kinase activity 0.3636158632497551 0.1100479735623851 0.9123713285299582 1.0 1.0 5 Q00535 1 +Phosphatidylinositol 3 4 5 trisphosphate binding 0.3254986723643166 0.1098215438903571 0.912550904835407 1.0 1.0 11 P31749 1 +Single stranded telomeric dna binding 0.3435178570234568 0.1085653231174944 0.9135472662776564 1.0 1.0 7 P22626 1 +Polypeptide n acetylgalactosaminyltransferase activity 0.4657245941070276 0.1070107575886526 0.9147804454415568 1.0 1.0 3 Q10471,Q10472 2 +Acetylgalactosaminyltransferase activity 0.4657245941070276 0.1070107575886526 0.9147804454415568 1.0 1.0 3 Q10471,Q10472 2 +Minor groove of adenine thymine rich dna binding 0.4060305411506523 0.102466773385655 0.918386184997334 1.0 1.0 4 Q14103 1 +Solute proton symporter activity 0.437030357679588 0.0974920660129402 0.9223356346219014 1.0 1.0 2 Q00325 1 +Mrna 3 utr au rich region binding 0.316301396466955 0.0939088436564928 0.925181568664377 1.0 1.0 12 Q92945,Q14103 2 +Sulfate binding 0.4322212203185986 0.0933807362972418 0.9256010938483624 1.0 1.0 2 P15586 1 +Sodium ion binding 0.4289149383829208 0.0906969798378387 0.9277333704823404 1.0 1.0 2 P05023 1 +Calmodulin dependent protein kinase activity 0.4271115118725531 0.0892811252956432 0.9288584939911856 1.0 1.0 2 Q14012 1 +S acyltransferase activity 0.3932729605040669 0.0853961922366535 0.9319464202614572 1.0 1.0 4 P49327 1 +Calcium ion transmembrane transporter activity 0.3139142847807537 0.0850341682928787 0.9322342267044128 1.0 1.0 12 Q9HC07,Q00535 2 +Magnesium ion transmembrane transporter activity 0.4180943793207117 0.0826942200103881 0.9340946808959516 1.0 1.0 2 Q8N4V1 1 +General transcription initiation factor activity 0.3888721804511315 0.0799817075330639 0.9362518046293788 1.0 1.0 4 P17480,P13984,Q00403 3 +1 acylglycerophosphocholine o acyltransferase activity 0.412684099789608 0.0791207953072917 0.9369365430999566 1.0 1.0 2 Q8NF37 1 +Protein tag 0.4012623985572559 0.0724480198964473 0.9422453708145568 1.0 1.0 2 P61956 1 +Retinal dehydrogenase activity 0.3934475503456573 0.0685162307890471 0.945374700136141 1.0 1.0 2 O94788 1 +Polyubiquitin modification dependent protein binding 0.2869614744606706 0.0684566305865714 0.9454221428245582 1.0 1.0 20 P46379 1 +Nucleoside diphosphatase activity 0.3883378418996158 0.066202982799633 0.9472162220559646 1.0 1.0 2 Q9UKK9 1 +Chloride ion binding 0.3883378418996003 0.0662029827996263 0.94721622205597 1.0 1.0 2 P53634 1 +Signal recognition particle binding 0.3384476534296071 0.0658317597566992 0.9475117704433202 1.0 1.0 5 P49458,Q9UHB9,Q9BUN8,O76094 4 +Alpha actinin binding 0.3366425992779834 0.063038577244152 0.949735785195196 1.0 1.0 5 Q8WX93,Q53GG5,Q9NR12,Q96HC4 4 +Muscle alpha actinin binding 0.3366425992779834 0.063038577244152 0.949735785195196 1.0 1.0 5 Q8WX93,Q53GG5,Q9NR12,Q96HC4 4 +Phosphatidylcholine transporter activity 0.4183037786499443 0.0628010824236268 0.9499249039230326 1.0 1.0 3 P08183 1 +Histone h3 methyl lysine 9 demethylase activity 0.3731989868036831 0.0626129803850897 0.9500746928476308 1.0 1.0 4 O75151 1 +Endoribonuclease activity 0.2851989515097882 0.0615169118770365 0.9509475461835422 1.0 1.0 22 Q9UQ84 1 +Carbon carbon lyase activity 0.287813734344935 0.0589185067481744 0.9530170174040902 1.0 1.0 18 O95470 1 +Adp binding 0.284020954950556 0.0542620239341191 0.956726405465363 1.0 1.0 19 Q92614,Q03518 2 +Ccr chemokine receptor binding 0.3950691521346923 0.0486966193072393 0.9611610700833086 1.0 1.0 3 P48681,P42224 2 +Rna polymerase ii general transcription initiation factor activity 0.3887552615754719 0.0455898022719598 0.9636371973303413 1.0 1.0 3 P13984,Q00403 2 +Sequence specific single stranded dna binding 0.3072621781142524 0.0424937171539664 0.96610512021302 1.0 1.0 8 P22626 1 +Kinetochore binding 0.3204281443306979 0.040174127056286 0.9679543045908492 1.0 1.0 5 Q02224 1 +Eukaryotic initiation factor 4e binding 0.3695129284425779 0.0377857978096877 0.9698584679923364 1.0 1.0 3 O00571,Q6PKG0 2 +Plus end directed microtubule motor activity 0.3047150369085324 0.0358942438736937 0.9713666856349672 1.0 1.0 8 Q15058,Q02224 2 +Map kinase activity 0.361329264957037 0.0351463194130999 0.9719630666580276 1.0 1.0 3 P28482 1 +Guanyl nucleotide exchange factor activity 0.2780153185568432 0.0343563114618731 0.9725930212903928 1.0 1.0 37 P80303 1 +Protein kinase a regulatory subunit binding 0.3038761587834091 0.0337509458383358 0.973075753186594 1.0 1.0 8 O43823,Q9ULX6 2 +Rna directed dna polymerase activity 0.3559831629585093 0.033616110631515 0.9731832751028712 1.0 1.0 3 Q15554,Q15185 2 +Telomerase activity 0.3559831629585093 0.033616110631515 0.9731832751028712 1.0 1.0 3 Q15554,Q15185 2 +Nucleocytoplasmic carrier activity 0.2798381875852385 0.0329209642769689 0.9737376147802546 1.0 1.0 21 Q9HAV4,Q8TEX9,Q9UI26,O15504,Q92973 5 +Acetyl coa hydrolase activity 0.3523752254960921 0.0326643755636735 0.9739422329039344 1.0 1.0 3 O14734,Q9Y305 2 +Tropomyosin binding 0.3340348767288079 0.0287252527791897 0.97708371587 1.0 1.0 3 Q9NYL9,P28289 2 +Ap 2 adaptor complex binding 0.3301262778111882 0.0280582658025604 0.9776156800218164 1.0 1.0 3 Q5SW96,O00291 2 +Opsonin binding 0.3104811954133415 0.0254494425332623 0.9796964744233524 1.0 1.0 3 Q07021 1 +Complement binding 0.3104811954133415 0.0254494425332623 0.9796964744233524 1.0 1.0 3 Q07021 1 +Mitogen activated protein kinase p38 binding 0.251352976548414 0.0223147832310767 0.9821968565057388 1.0 1.0 3 Q99873,Q16539 2 +Gtp dependent protein binding 0.2952080917151394 0.0127250096201764 0.9898471852892916 1.0 1.0 10 Q9BZG1,Q86YV9,P53365,P61020 4 +Cytokine binding 0.3032253709386893 0.0121003036398966 0.9903455901407896 1.0 1.0 6 P15260 1 +Transferase activity transferring one carbon groups 0.2679817148160923 0.0098423364092079 0.9921470785245629 1.0 1.0 65 O96028,Q86VU5,O75648,Q08J23,Q9BV86,Q03164,P21964,Q6P2P2,Q52LJ0,P34897,P34896,Q8IZ69,O60725,Q96RS0 14 +Histone methyltransferase activity h3 k4 specific 0.2905332942760581 0.008014947524033 0.9936050655827766 1.0 1.0 5 Q03164 1 +Annealing activity 0.2919792453488498 0.0010236465069798 0.9991832483990002 1.0 1.0 11 Q06787,P23588,Q15056,P51114 4 +Metal dependent deubiquitinase activity 0.2953040337146278 0.0007766248675591 0.9993803430709296 1.0 1.0 7 O15372,O00487,Q92905,O00303,Q6P2Q9,P51665 6 diff --git a/msigdb_gomf/selections.json b/msigdb_gomf/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..bef904716d8f49b60a5b89606e9025c6a6865775 --- /dev/null +++ b/msigdb_gomf/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1 4 alpha oligoglucan phosphorylase activity", "1 acylglycerophosphocholine o acyltransferase activity", "1 alkyl 2 acetylglycerophosphocholine esterase activity", "1 phosphatidylinositol 3 kinase activity", "1 phosphatidylinositol 4 kinase activity", "1 phosphatidylinositol 4 phosphate 3 kinase activity", "1 phosphatidylinositol 4 phosphate 5 kinase activity", "1 phosphatidylinositol binding", "14 3 3 protein binding", "17 beta hydroxysteroid dehydrogenase nadplus activity", "17 beta hydroxysteroid dehydrogenase nadpplus activity", "2 acylglycerol 3 phosphate o acyltransferase activity", "2 acylglycerol o acyltransferase activity", "2 iron 2 sulfur cluster binding", "2 oxoglutarate dependent dioxygenase activity", "3 5 dna helicase activity", "3 5 exodeoxyribonuclease activity", "3 5 exonuclease activity", "3 beta hydroxy delta5 steroid dehydrogenase activity", "3 hydroxyacyl coa dehydratase activity", "3 hydroxyacyl coa dehydrogenase activity", "4 iron 4 sulfur cluster binding", "5 3 dna helicase activity", "5 3 exodeoxyribonuclease activity", "5 3 exonuclease activity", "5 deoxyribose 5 phosphate lyase activity", "5s rrna binding", "7s rna binding", "7sk snrna binding", "Abc type glutathione s conjugate transporter activity", "Abc type transporter activity", "Abc type xenobiotic transporter activity", "Acetyl coa c acetyltransferase activity", "Acetyl coa c acyltransferase activity", "Acetyl coa hydrolase activity", "Acetylcholine receptor binding", "Acetylgalactosaminyltransferase activity", "Acetylglucosaminyltransferase activity", "Acetyltransferase activity", "Acid amino acid ligase activity", "Acid phosphatase activity", "Acid thiol ligase activity", "Acidic amino acid transmembrane transporter activity", "Actin binding", "Actin filament binding", "Actin monomer binding", "Actinin binding", "Active ion transmembrane transporter activity", "Active transmembrane transporter activity", "Activin binding", "Acyl carnitine transmembrane transporter activity", "Acyl coa binding", "Acyl coa dehydrogenase activity", "Acyl coa oxidase activity", "Acylglycerol lipase activity", "Acylglycerol o acyltransferase activity", "Acyltransferase activity", "Acyltransferase acyl groups converted into alkyl on transfer", "Adenosine deaminase activity", "Adenyl nucleotide binding", "Adenyl nucleotide exchange factor activity", "Adenylate cyclase binding", "Adenylate kinase activity", "Adenylyltransferase activity", "Adp binding", "Adp ribose diphosphatase activity", "Adp transmembrane transporter activity", "Adrenergic receptor binding", "Alanine transmembrane transporter activity", "Alcohol binding", "Alcohol dehydrogenase activity zinc dependent", "Alcohol dehydrogenase nad p plus activity", "Alcohol dehydrogenase nadpplus activity", "Aldehyde dehydrogenase nad p plus activity", "Aldehyde lyase activity", "Alditol nadpplus 1 oxidoreductase activity", "Aldo keto reductase nadp activity", "Alkali metal ion binding", "Alpha actinin binding", "Alpha catenin binding", "Alpha glucosidase activity", "Alpha tubulin binding", "Amide binding", "Amide transmembrane transporter activity", "Amidine lyase activity", "Amino acid binding", "Amino acid cation symporter activity", "Amino acid proton symporter activity", "Amino acid sodium symporter activity", "Amino acid transmembrane transporter activity", "Aminoacyl trna editing activity", "Aminoacylase activity", "Aminoacyltransferase activity", "Aminopeptidase activity", "Aminophospholipid flippase activity", "Ammonium transmembrane transporter activity", "Amp activated protein kinase activity", "Amp binding", "Amyloid beta binding", "Anaphase promoting complex binding", "Androgen receptor binding", "Androstan 3 alpha 17 beta diol dehydrogenase activity", "Anion cation symporter activity", "Anion channel activity", "Anion sodium symporter activity", "Anion transmembrane transporter activity", "Ankyrin binding", "Ankyrin repeat binding", "Annealing activity", "Antigen binding", "Antioxidant activity", "Antiporter activity", "Ap 1 adaptor complex binding", "Ap 2 adaptor complex binding", "Apolipoprotein a i binding", "Apolipoprotein binding", "Apolipoprotein receptor binding", "Arachidonate coa ligase activity", "Arginine binding", "Armadillo repeat domain binding", "Aromatic amino acid transmembrane transporter activity", "Arp2 3 complex binding", "Arrestin family protein binding", "Aryl hydrocarbon receptor binding", "Arylesterase activity", "Arylsulfatase activity", "Aspartic endopeptidase activity intramembrane cleaving", "Aspartic type endopeptidase inhibitor activity", "Aspartic type peptidase activity", "Atp dependent activity", "Atp dependent activity acting on dna", "Atp dependent activity acting on rna", "Atp dependent chromatin remodeler activity", "Atp dependent dna dna annealing activity", "Atp dependent peptidase activity", "Atp dependent protein binding", "Atp gated ion channel activity", "Atp hydrolysis activity", "Atp transmembrane transporter activity", "Atpase activator activity", "Atpase binding", "Atpase coupled cation transmembrane transporter activity", "Atpase coupled inorganic anion transmembrane transporter activity", "Atpase coupled intramembrane lipid transporter activity", "Atpase coupled ion transmembrane transporter activity", "Atpase coupled lipid transmembrane transporter activity", "Atpase coupled transmembrane transporter activity", "Atpase inhibitor activity", "Atpase regulator activity", "Basal transcription machinery binding", "Benzodiazepine receptor activity", "Beta 1 3 galactosyltransferase activity", "Beta 2 adrenergic receptor binding", "Beta 2 microglobulin binding", "Beta catenin binding", "Beta galactosidase activity", "Beta n acetylhexosaminidase activity", "Beta tubulin binding", "Bh domain binding", "Bh3 domain binding", "Bhlh transcription factor binding", "Bile acid binding", "Bile acid transmembrane transporter activity", "Bioactive lipid receptor activity", "Biotin binding", "Box h aca snorna binding", "Branched chain amino acid transmembrane transporter activity", "Bubble dna binding", "C acetyltransferase activity", "C acyltransferase activity", "C methyltransferase activity", "C palmitoyltransferase activity", "C x c chemokine binding", "C x3 c chemokine binding", "C2h2 zinc finger domain binding", "C3hc4 type ring finger domain binding", "C4 dicarboxylate transmembrane transporter activity", "Cadherin binding", "Cadherin binding involved in cell cell adhesion", "Calcium activated cation channel activity", "Calcium cation antiporter activity", "Calcium channel inhibitor activity", "Calcium channel regulator activity", "Calcium dependent cysteine type endopeptidase activity", "Calcium dependent phospholipid binding", "Calcium dependent protein binding", "Calcium dependent protein kinase activity", "Calcium dependent protein serine threonine phosphatase activity", "Calcium independent phospholipase a2 activity", "Calcium ion binding", "Calcium ion transmembrane transporter activity", "Calmodulin binding", "Calmodulin dependent protein kinase activity", "Calmodulin dependent protein phosphatase activity", "Camp binding", "Camp dependent protein kinase activity", "Camp dependent protein kinase inhibitor activity", "Camp dependent protein kinase regulator activity", "Carbohydrate binding", "Carbohydrate derivative transmembrane transporter activity", "Carbohydrate kinase activity", "Carbohydrate phosphatase activity", "Carbon carbon lyase activity", "Carbon nitrogen ligase activity with glutamine as amido n donor", "Carbon nitrogen lyase activity", "Carbon oxygen lyase activity", "Carbon sulfur lyase activity", "Carbonyl reductase nadph activity", "Carboxy lyase activity", "Carboxylic acid binding", "Carboxylic ester hydrolase activity", "Carboxypeptidase activity", "Card domain binding", "Cardiolipin binding", "Cargo adaptor activity", "Cargo receptor activity", "Carnitine o acyltransferase activity", "Catalytic activity acting on a glycoprotein", "Catalytic activity acting on a nucleic acid", "Catalytic activity acting on a rrna", "Catalytic activity acting on a trna", "Catalytic activity acting on dna", "Catalytic activity acting on rna", "Cation cation antiporter activity", "Cation channel activity", "Cation chloride symporter activity", "Cation transmembrane transporter activity", "Ccr chemokine receptor binding", "Ccr3 chemokine receptor binding", "Ccr5 chemokine receptor binding", "Cdp alcohol phosphatidyltransferase activity", "Cell adhesion mediator activity", "Cell adhesion molecule binding", "Cell adhesive protein binding involved in bundle of his cell purkinje myocyte communication", "Cell cell adhesion mediator activity", "Cell matrix adhesion mediator activity", "Centromeric dna binding", "Ceramide binding", "Cgmp binding", "Channel activator activity", "Channel inhibitor activity", "Channel regulator activity", "Chaperone binding", "Chemoattractant activity", "Chemokine binding", "Chemokine receptor binding", "Chitin binding", "Chloride channel inhibitor activity", "Chloride channel regulator activity", "Chloride ion binding", "Cholesterol binding", "Chondroitin sulfate binding", "Chromatin binding", "Chromatin dna binding", "Chromatin insulator sequence binding", "Chromo shadow domain binding", "Cis regulatory region sequence specific dna binding", "Cis trans isomerase activity", "Class i dna apurinic or apyrimidinic site endonuclease activity", "Clathrin binding", "Clathrin heavy chain binding", "Clathrin light chain binding", "Co smad binding", "Coa hydrolase activity", "Coa transferase activity", "Cobalamin binding", "Collagen binding", "Collagen binding involved in cell matrix adhesion", "Complement binding", "Complement component c1q complex binding", "Complement component c3b binding", "Copper chaperone activity", "Copper ion binding", "Core promoter sequence specific dna binding", "Coreceptor activity", "Coreceptor activity involved in wnt signaling pathway", "Coreceptor activity involved in wnt signaling pathway planar cell polarity pathway", "Cullin family protein binding", "Cuprous ion binding", "Cxcr chemokine receptor binding", "Cyclase activity", "Cyclase regulator activity", "Cyclic nucleotide binding", "Cyclic nucleotide dependent protein kinase activity", "Cyclic nucleotide phosphodiesterase activity", "Cyclin binding", "Cyclin dependent protein kinase activity", "Cyclin dependent protein serine threonine kinase activator activity", "Cyclin dependent protein serine threonine kinase inhibitor activity", "Cyclin dependent protein serine threonine kinase regulator activity", "Cyclohydrolase activity", "Cyclosporin a binding", "Cysteine type endopeptidase activity", "Cysteine type endopeptidase activity involved in apoptotic process", "Cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Cysteine type endopeptidase inhibitor activity", "Cysteine type endopeptidase inhibitor activity involved in apoptotic process", "Cysteine type endopeptidase regulator activity involved in apoptotic process", "Cysteine type exopeptidase activity", "Cysteine type peptidase activity", "Cytidine deaminase activity", "Cytidylyltransferase activity", "Cytochrome b5 reductase activity acting on nad p h", "Cytokine activity", "Cytokine binding", "Cytokine receptor activity", "Cytokine receptor binding", "Cytoskeletal anchor activity", "Cytoskeletal motor activity", "Cytoskeletal protein binding", "Cytoskeleton nuclear membrane anchor activity", "D loop dna binding", "D threo aldose 1 dehydrogenase activity", "D1 dopamine receptor binding", "Damaged dna binding", "Deacetylase activity", "Dead h box rna helicase binding", "Deaminase activity", "Death domain binding", "Death receptor activity", "Death receptor binding", "Demethylase activity", "Deoxycytidine deaminase activity", "Deoxynucleoside kinase activity", "Deoxyribonuclease activity", "Deoxyribonuclease i activity", "Diacylglycerol binding", "Diacylglycerol kinase activity", "Dicarboxylic acid transmembrane transporter activity", "Dihydropyrimidinase activity", "Dioxygenase activity", "Dipeptidase activity", "Dipeptidyl peptidase activity", "Diphosphotransferase activity", "Disordered domain specific binding", "Disulfide oxidoreductase activity", "Dna apurinic or apyrimidinic site endonuclease activity", "Dna binding bending", "Dna binding transcription activator activity", "Dna binding transcription factor activity", "Dna binding transcription factor binding", "Dna binding transcription repressor activity", "Dna clamp loader activity", "Dna directed dna polymerase activity", "Dna dna annealing activity", "Dna helicase activity", "Dna insertion or deletion binding", "Dna methyltransferase activity", "Dna n glycosylase activity", "Dna polymerase activity", "Dna polymerase binding", "Dna replication origin binding", "Dna secondary structure binding", "Dna topoisomerase activity", "Dna translocase activity", "Dolichyl diphosphooligosaccharide protein glycotransferase activity", "Dolichyl phosphate mannose protein mannosyltransferase activity", "Dopamine receptor binding", "Double stranded methylated dna binding", "Double stranded rna adenosine deaminase activity", "Double stranded rna binding", "Double stranded telomeric dna binding", "Dttp diphosphatase activity", "Dynactin binding", "Dynein complex binding", "Dynein heavy chain binding", "Dynein intermediate chain binding", "Dynein light chain binding", "Dynein light intermediate chain binding", "Dystroglycan binding", "E box binding", "Efflux transmembrane transporter activity", "Electron transfer activity", "Endodeoxyribonuclease activity", "Endodeoxyribonuclease activity producing 5 phosphomonoesters", "Endonuclease activity", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 3 phosphomonoesters", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Endopeptidase activator activity", "Endopeptidase activity", "Endopeptidase regulator activity", "Endopolyphosphatase activity", "Endoribonuclease activity", "Endoribonuclease activity producing 3 phosphomonoesters", "Endoribonuclease activity producing 5 phosphomonoesters", "Enoyl coa hydratase activity", "Enzyme activator activity", "Enzyme inhibitor activity", "Enzyme regulator activity", "Ephrin receptor binding", "Epidermal growth factor receptor binding", "Epoxide hydrolase activity", "Er retention sequence binding", "Erbb 3 class receptor binding", "Estradiol 17 beta dehydrogenase activity", "Estrogen receptor binding", "Ether hydrolase activity", "Eukaryotic initiation factor 4e binding", "Exodeoxyribonuclease activity", "Exogenous protein binding", "Exonuclease activity", "Exonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Exopeptidase activity", "Exoribonuclease activity", "Exoribonuclease activity producing 5 phosphomonoesters", "Extracellular matrix binding", "Extracellular matrix constituent conferring elasticity", "Extracellular matrix structural constituent", "Fad binding", "Fatty acid binding", "Fatty acid derivative binding", "Fatty acid ligase activity", "Fatty acid synthase activity", "Fatty acid transmembrane transporter activity", "Fatz binding", "Ferric iron binding", "Ferrous iron binding", "Fibroblast growth factor binding", "Fibroblast growth factor receptor binding", "Fibronectin binding", "Filamin binding", "Fk506 binding", "Flap endonuclease activity", "Flavin adenine dinucleotide binding", "Flippase activity", "Floppase activity", "Fmn binding", "Folic acid binding", "Folic acid transmembrane transporter activity", "Four way junction dna binding", "Four way junction helicase activity", "Frizzled binding", "Fructose 2 6 bisphosphate 2 phosphatase activity", "Fructose 6 phosphate binding", "Fructose binding", "Fucosyltransferase activity", "G protein activity", "G protein alpha subunit binding", "G protein beta gamma subunit complex binding", "G protein beta subunit binding", "G protein coupled glutamate receptor binding", "G protein coupled opioid receptor activity", "G protein coupled receptor activity", "G protein coupled receptor binding", "G protein coupled serotonin receptor binding", "G quadruplex dna binding", "G quadruplex rna binding", "G rich strand telomeric dna binding", "Gaba receptor binding", "Galactosidase activity", "Galactoside binding", "Galactosyltransferase activity", "Gamma aminobutyric acid transmembrane transporter activity", "Gamma catenin binding", "Gamma tubulin binding", "Ganglioside binding", "Gated channel activity", "Gdp binding", "Gdp dissociation inhibitor activity", "General transcription initiation factor activity", "General transcription initiation factor binding", "Glucocorticoid receptor binding", "Glucose binding", "Glucosidase activity", "Glucosyltransferase activity", "Glucuronosyltransferase activity", "Glutamate receptor binding", "Glutathione disulfide oxidoreductase activity", "Glutathione hydrolase activity", "Glutathione oxidoreductase activity", "Glutathione peroxidase activity", "Glutathione transferase activity", "Glutathione transmembrane transporter activity", "Glyceraldehyde 3 phosphate dehydrogenase nadplus non phosphorylating activity", "Glycerophospholipid flippase activity", "Glycine binding", "Glycolipid binding", "Glycolipid mannosyltransferase activity", "Glycosaminoglycan binding", "Glycosphingolipid binding", "Glycosyltransferase activity", "Gpi anchor binding", "Growth factor activity", "Growth factor binding", "Growth factor receptor binding", "Gtp dependent protein binding", "Gtpase activating protein binding", "Gtpase activator activity", "Gtpase activity", "Gtpase binding", "Gtpase inhibitor activity", "Guanyl nucleotide binding", "Guanyl nucleotide exchange factor activity", "Guanylate kinase activity", "Guanylyltransferase activity", "H4 histone acetyltransferase activity", "Heat shock protein binding", "Helicase activity", "Heme transmembrane transporter activity", "Heparan sulfate proteoglycan binding", "Heparan sulfate sulfotransferase activity", "Heparin binding", "Hexokinase activity", "Hexosaminidase activity", "Hexosyltransferase activity", "High density lipoprotein particle binding", "Histone acetyltransferase binding", "Histone arginine n methyltransferase activity", "Histone binding", "Histone deacetylase activity h3 k14 specific", "Histone deacetylase binding", "Histone deacetylase regulator activity", "Histone h3 di monomethyl lysine 9 demethylase activity", "Histone h3 methyl lysine 36 demethylase activity", "Histone h3 methyl lysine 4 demethylase activity", "Histone h3 methyl lysine 9 demethylase activity", "Histone h3 tri di methyl lysine 27 demethylase activity", "Histone h3 tri di monomethyl lysine 4 demethylase activity", "Histone kinase activity", "Histone lysine n methyltransferase activity", "Histone methyltransferase activity", "Histone methyltransferase activity h3 k36 specific", "Histone methyltransferase activity h3 k4 specific", "Histone methyltransferase activity h3 k9 specific", "Histone methyltransferase activity h4 k20 specific", "Histone methyltransferase binding", "Histone serine kinase activity", "Histone threonine kinase activity", "Hormone activity", "Hormone binding", "Hormone receptor binding", "Hsp70 protein binding", "Hsp90 protein binding", "Hyaluronic acid binding", "Hyalurononglucosaminidase activity", "Hydro lyase activity", "Hydrolase activity acting on acid anhydrides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amidines", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amides", "Hydrolase activity acting on ester bonds", "Hydrolase activity acting on ether bonds", "Hydrolase activity acting on glycosyl bonds", "Hydrolase activity hydrolyzing n glycosyl compounds", "Hydrolase activity hydrolyzing o glycosyl compounds", "Hydroxymethyl formyl and related transferase activity", "Hypoglycin a gamma glutamyl transpeptidase activity", "I smad binding", "Identical protein binding", "Immune receptor activity", "Immunoglobulin binding", "Immunoglobulin receptor binding", "Importin alpha family protein binding", "Inorganic anion transmembrane transporter activity", "Inorganic diphosphatase activity", "Inorganic molecular entity transmembrane transporter activity", "Inorganic phosphate transmembrane transporter activity", "Inositol 1 4 5 trisphosphate 5 phosphatase activity", "Inositol bisphosphate phosphatase activity", "Inositol phosphate phosphatase activity", "Inositol polyphosphate 5 phosphatase activity", "Inositol tetrakisphosphate phosphatase activity", "Inositol trisphosphate phosphatase activity", "Insulin binding", "Insulin like growth factor binding", "Insulin like growth factor i binding", "Insulin like growth factor ii binding", "Insulin like growth factor receptor binding", "Insulin receptor binding", "Insulin receptor substrate binding", "Integrin binding", "Interferon receptor activity", "Interleukin 1 binding", "Interleukin 1 receptor binding", "Interleukin 2 receptor binding", "Interleukin 6 receptor binding", "Intermediate filament binding", "Intracellular calcium activated chloride channel activity", "Intraciliary transport particle b binding", "Intramembrane lipid transporter activity", "Intramolecular oxidoreductase activity", "Intramolecular oxidoreductase activity interconverting aldoses and ketoses", "Intramolecular oxidoreductase activity transposing c c bonds", "Intramolecular transferase activity", "Intramolecular transferase activity phosphotransferases", "Ion gated channel activity", "Ion transmembrane transporter activity", "Ionotropic glutamate receptor binding", "Iron ion binding", "Iron ion transmembrane transporter activity", "Isocitrate dehydrogenase activity", "Isomerase activity", "Isopeptidase activity", "Isoprenoid binding", "Jun kinase binding", "Jun kinase kinase kinase activity", "K48 linked polyubiquitin modification dependent protein binding", "K63 linked polyubiquitin modification dependent protein binding", "Keratin filament binding", "Kinase activator activity", "Kinase activity", "Kinase binding", "Kinase inhibitor activity", "Kinase regulator activity", "Kinesin binding", "Kinetochore binding", "L alanine transmembrane transporter activity", "L amino acid transmembrane transporter activity", "L ascorbic acid binding", "L aspartate transmembrane transporter activity", "L glutamine transmembrane transporter activity", "L lactate dehydrogenase activity", "L leucine transmembrane transporter activity", "L ornithine transmembrane transporter activity", "L serine transmembrane transporter activity", "Lactate dehydrogenase activity", "Lactate transmembrane transporter activity", "Lamin binding", "Laminin 1 binding", "Laminin binding", "Large ribosomal subunit rrna binding", "Lbd domain binding", "Leucine binding", "Leucine zipper domain binding", "Leukotriene c4 synthase activity", "Ligand gated cation channel activity", "Ligand gated ion channel activity", "Ligase activity", "Ligase activity forming carbon carbon bonds", "Ligase activity forming carbon nitrogen bonds", "Ligase activity forming carbon oxygen bonds", "Ligase activity forming carbon sulfur bonds", "Ligase activity forming phosphoric ester bonds", "Lim domain binding", "Lipase activator activity", "Lipase activity", "Lipase binding", "Lipase inhibitor activity", "Lipid binding", "Lipid kinase activity", "Lipid phosphatase activity", "Lipid transfer activity", "Lipid transporter activity", "Lipopolysaccharide binding", "Lipopolysaccharide immune receptor activity", "Lipoprotein particle receptor activity", "Lipoprotein particle receptor binding", "Long chain acyl coa dehydrogenase activity", "Long chain fatty acid binding", "Long chain fatty acid coa ligase activity", "Long chain fatty acid transporter activity", "Long chain fatty acyl coa binding", "Low density lipoprotein particle binding", "Low density lipoprotein particle receptor activity", "Low density lipoprotein particle receptor binding", "Lrr domain binding", "Lyase activity", "Lys48 specific deubiquitinase activity", "Lys63 specific deubiquitinase activity", "Lysine acetylated histone binding", "Lysine n methyltransferase activity", "Lysophosphatidic acid binding", "Lysophosphatidic acid phosphatase activity", "Lysophospholipase activity", "Lysophospholipid acyltransferase activity", "M7g 5 pppn diphosphatase activity", "Macrolide binding", "Macromolecule transmembrane transporter activity", "Magnesium ion binding", "Magnesium ion transmembrane transporter activity", "Malate dehydrogenase activity", "Manganese ion binding", "Manganese ion transmembrane transporter activity", "Mannose binding", "Mannosidase activity", "Mannosyl oligosaccharide 1 2 alpha mannosidase activity", "Mannosyl oligosaccharide mannosidase activity", "Mannosyltransferase activity", "Map kinase activity", "Map kinase kinase activity", "Map kinase kinase kinase activity", "Map kinase phosphatase activity", "Map kinase scaffold activity", "Map kinase tyrosine serine threonine phosphatase activity", "Mdm2 mdm4 family protein binding", "Mechanosensitive ion channel activity", "Medium chain fatty acid coa ligase activity", "Membrane insertase activity", "Metal cluster binding", "Metal dependent deubiquitinase activity", "Metal ion proton antiporter activity", "Metal ion transmembrane transporter activity", "Metalloaminopeptidase activity", "Metallocarboxypeptidase activity", "Metallochaperone activity", "Metallodipeptidase activity", "Metalloendopeptidase activity", "Metalloexopeptidase activity", "Metallopeptidase activity", "Methyl cpg binding", "Methylated histone binding", "Mhc class i protein binding", "Mhc class ib protein binding", "Mhc class ii protein complex binding", "Mhc protein binding", "Mhc protein complex binding", "Microfilament motor activity", "Microtubule binding", "Microtubule minus end binding", "Microtubule motor activity", "Microtubule plus end binding", "Minor groove of adenine thymine rich dna binding", "Minus end directed microtubule motor activity", "Mirna binding", "Misfolded protein binding", "Mismatch repair complex binding", "Mismatched dna binding", "Mitochondrial ribosome binding", "Mitochondrion targeting sequence binding", "Mitogen activated protein kinase binding", "Mitogen activated protein kinase kinase binding", "Mitogen activated protein kinase kinase kinase binding", "Mitogen activated protein kinase p38 binding", "Modification dependent protein binding", "Modified amino acid binding", "Modified amino acid transmembrane transporter activity", "Molecular adaptor activity", "Molecular carrier activity", "Molecular function activator activity", "Molecular function inhibitor activity", "Molecular function regulator", "Molecular sequestering activity", "Molecular transducer activity", "Molybdopterin cofactor binding", "Monocarboxylic acid binding", "Monocarboxylic acid transmembrane transporter activity", "Monooxygenase activity", "Monosaccharide binding", "Mrf binding", "Mrna 3 utr au rich region binding", "Mrna 3 utr binding", "Mrna 5 utr binding", "Mrna binding", "Mrna methyltransferase activity", "Muscle alpha actinin binding", "Mutlalpha complex binding", "Myosin binding", "Myosin ii binding", "Myosin v binding", "Myristoyltransferase activity", "N acetylgalactosamine 4 o sulfotransferase activity", "N acetyllactosamine synthase activity", "N acetyllactosaminide beta 1 3 n acetylglucosaminyltransferase activity", "N acetyltransferase activity", "N acylsphingosine amidohydrolase activity", "N acyltransferase activity", "N methyltransferase activity", "N6 methyladenosine containing rna binding", "Nad binding", "Nad dependent protein deacetylase activity", "Nad p h oxidase h2o2 forming activity", "Nad p plus protein arginine adp ribosyltransferase activity", "Nad retinol dehydrogenase activity", "Nadh dehydrogenase activity", "Nadh pyrophosphatase activity", "Nadp binding", "Nadp retinol dehydrogenase activity", "Nadph binding", "Nadplus adp ribosyltransferase activity", "Nadplus binding", "Nadplus kinase activity", "Nedd8 specific protease activity", "Nedd8 transferase activity", "Nerve growth factor binding", "Neurexin family protein binding", "Neuroligin family protein binding", "Neurotransmitter binding", "Neurotransmitter receptor activity", "Neurotransmitter receptor regulator activity", "Neurotransmitter transmembrane transporter activity", "Neurotrophin binding", "Neurotrophin receptor activity", "Neurotrophin receptor binding", "Neurotrophin trk receptor binding", "Neutral amino acid transmembrane transporter activity", "Nf kappab binding", "Nfat protein binding", "Nitric oxide synthase binding", "Nitric oxide synthase regulator activity", "Nitrite reductase activity", "Non membrane spanning protein tyrosine kinase activity", "Non membrane spanning protein tyrosine phosphatase activity", "Notch binding", "Nuclear export signal receptor activity", "Nuclear import signal receptor activity", "Nuclear localization sequence binding", "Nuclear receptor activity", "Nuclear receptor binding", "Nuclear receptor coactivator activity", "Nuclease activity", "Nucleobase containing compound kinase activity", "Nucleobase containing compound transmembrane transporter activity", "Nucleobase transmembrane transporter activity", "Nucleocytoplasmic carrier activity", "Nucleoside binding", "Nucleoside diphosphatase activity", "Nucleoside diphosphate kinase activity", "Nucleoside kinase activity", "Nucleoside monophosphate kinase activity", "Nucleoside triphosphatase regulator activity", "Nucleoside triphosphate diphosphatase activity", "Nucleosomal dna binding", "Nucleosome binding", "Nucleotidase activity", "Nucleotide diphosphatase activity", "Nucleotide phosphatase activity acting on free nucleotides", "Nucleotide sugar transmembrane transporter activity", "Nucleotide transmembrane transporter activity", "Nucleotidyltransferase activity", "O acetyltransferase activity", "O acyltransferase activity", "O methyltransferase activity", "O palmitoyltransferase activity", "Oleate transmembrane transporter activity", "Oligopeptide binding", "Oligopeptide transmembrane transporter activity", "Oligosaccharide binding", "Oligosaccharyl transferase activity", "Omega peptidase activity", "Opsonin binding", "Organic acid binding", "Organic acid sodium symporter activity", "Organic acid transmembrane transporter activity", "Organic anion transmembrane transporter activity", "Organic cation transmembrane transporter activity", "Organic hydroxy compound transmembrane transporter activity", "Organophosphate ester transmembrane transporter activity", "Oxidative phosphorylation uncoupler activity", "Oxidative rna demethylase activity", "Oxidized dna binding", "Oxidoreductase activity", "Oxidoreductase activity acting on a heme group of donors", "Oxidoreductase activity acting on a sulfur group of donors", "Oxidoreductase activity acting on a sulfur group of donors disulfide as acceptor", "Oxidoreductase activity acting on a sulfur group of donors nad p as acceptor", "Oxidoreductase activity acting on a sulfur group of donors oxygen as acceptor", "Oxidoreductase activity acting on ch oh group of donors", "Oxidoreductase activity acting on ch or ch2 groups", "Oxidoreductase activity acting on diphenols and related substances as donors", "Oxidoreductase activity acting on nad p h", "Oxidoreductase activity acting on nad p h heme protein as acceptor", "Oxidoreductase activity acting on nad p h oxygen as acceptor", "Oxidoreductase activity acting on nad p h quinone or similar compound as acceptor", "Oxidoreductase activity acting on other nitrogenous compounds as donors", "Oxidoreductase activity acting on other nitrogenous compounds as donors cytochrome as acceptor", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen nad p h as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced ascorbate as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced flavin or flavoprotein as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced pteridine as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water", "Oxidoreductase activity acting on peroxide as acceptor", "Oxidoreductase activity acting on single donors with incorporation of molecular oxygen", "Oxidoreductase activity acting on the aldehyde or oxo group of donors", "Oxidoreductase activity acting on the aldehyde or oxo group of donors disulfide as acceptor", "Oxidoreductase activity acting on the aldehyde or oxo group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors", "Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors oxygen as acceptor", "Oxidoreductase activity acting on the ch nh group of donors", "Oxidoreductase activity acting on the ch nh group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch nh2 group of donors", "Oxidoreductase activity acting on the ch nh2 group of donors oxygen as acceptor", "Oxidoreduction driven active transmembrane transporter activity", "Oxo acid lyase activity", "Oxygen binding", "Oxygen sensor activity", "Oxysterol binding", "P type calcium transporter activity", "P type potassium transmembrane transporter activity", "P type transmembrane transporter activity", "P53 binding", "Palmitoyl coa hydrolase activity", "Palmitoyl protein hydrolase activity", "Palmitoyltransferase activity", "Passive transmembrane transporter activity", "Patched binding", "Pattern recognition receptor activity", "Pdz domain binding", "Pentosyltransferase activity", "Peptidase activator activity", "Peptidase activator activity involved in apoptotic process", "Peptidase activity", "Peptidase regulator activity", "Peptide alpha n acetyltransferase activity", "Peptide antigen binding", "Peptide binding", "Peptide hormone binding", "Peptide hormone receptor binding", "Peptide lysine n acetyltransferase activity", "Peptide n acetyltransferase activity", "Peptide receptor activity", "Peptide transmembrane transporter activity", "Peptidoglycan binding", "Peptidyl proline 4 dioxygenase activity", "Peptidyl proline dioxygenase activity", "Peroxiredoxin activity", "Peroxisome proliferator activated receptor binding", "Peroxisome targeting sequence binding", "Phosphatase activator activity", "Phosphatase activity", "Phosphatase binding", "Phosphatase inhibitor activity", "Phosphatase regulator activity", "Phosphate ion binding", "Phosphatidic acid binding", "Phosphatidyl phospholipase b activity", "Phosphatidylcholine binding", "Phosphatidylcholine floppase activity", "Phosphatidylcholine transfer activity", "Phosphatidylcholine transporter activity", "Phosphatidylethanolamine binding", "Phosphatidylethanolamine flippase activity", "Phosphatidylglycerol binding", "Phosphatidylinositol 3 4 5 trisphosphate 3 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate 5 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate binding", "Phosphatidylinositol 3 4 bisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate 3 phosphatase activity", "Phosphatidylinositol 3 5 bisphosphate 5 phosphatase activity", "Phosphatidylinositol 3 5 bisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate phosphatase activity", "Phosphatidylinositol 3 kinase activity", "Phosphatidylinositol 3 kinase binding", "Phosphatidylinositol 3 kinase regulator activity", "Phosphatidylinositol 3 kinase regulatory subunit binding", "Phosphatidylinositol 3 phosphate binding", "Phosphatidylinositol 4 5 bisphosphate 3 kinase activity", "Phosphatidylinositol 4 5 bisphosphate 5 phosphatase activity", "Phosphatidylinositol 4 5 bisphosphate binding", "Phosphatidylinositol 4 5 bisphosphate phosphatase activity", "Phosphatidylinositol 4 phosphate binding", "Phosphatidylinositol 5 phosphate binding", "Phosphatidylinositol binding", "Phosphatidylinositol bisphosphate binding", "Phosphatidylinositol bisphosphate kinase activity", "Phosphatidylinositol bisphosphate phosphatase activity", "Phosphatidylinositol kinase activity", "Phosphatidylinositol monophosphate phosphatase activity", "Phosphatidylinositol phosphate 4 phosphatase activity", "Phosphatidylinositol phosphate 5 phosphatase activity", "Phosphatidylinositol phosphate binding", "Phosphatidylinositol phosphate kinase activity", "Phosphatidylinositol phosphate phosphatase activity", "Phosphatidylinositol transfer activity", "Phosphatidylinositol trisphosphate phosphatase activity", "Phosphatidylserine 1 acylhydrolase activity", "Phosphatidylserine binding", "Phosphodiesterase i activity", "Phosphofructokinase activity", "Phospholipase a1 activity", "Phospholipase a2 activity", "Phospholipase a2 inhibitor activity", "Phospholipase activity", "Phospholipase binding", "Phospholipase c activity", "Phospholipase d activity", "Phospholipase inhibitor activity", "Phospholipid binding", "Phospholipid scramblase activity", "Phospholipid transfer activity", "Phospholipid transporter activity", "Phosphoprotein binding", "Phosphoprotein phosphatase activity", "Phosphoric diester hydrolase activity", "Phosphoric ester hydrolase activity", "Phosphorus oxygen lyase activity", "Phosphoserine residue binding", "Phosphotransferase activity for other substituted phosphate groups", "Phosphotransferase activity nitrogenous group as acceptor", "Phosphotransferase activity phosphate group as acceptor", "Phosphotyrosine residue binding", "Plus end directed microtubule motor activity", "Poly a binding", "Poly a specific ribonuclease activity", "Poly g binding", "Poly purine tract binding", "Poly pyrimidine tract binding", "Polynucleotide adenylyltransferase activity", "Polypeptide n acetylgalactosaminyltransferase activity", "Polysaccharide binding", "Polysome binding", "Polyubiquitin modification dependent protein binding", "Porin activity", "Potassium channel activity", "Potassium channel inhibitor activity", "Potassium channel regulator activity", "Potassium chloride symporter activity", "Potassium ion binding", "Potassium ion transmembrane transporter activity", "Pre mirna binding", "Pre mrna 3 splice site binding", "Pre mrna 5 splice site binding", "Pre mrna binding", "Pre mrna intronic binding", "Prenyltransferase activity", "Primary active transmembrane transporter activity", "Primary mirna binding", "Procollagen proline 4 dioxygenase activity", "Procollagen proline dioxygenase activity", "Profilin binding", "Proline rich region binding", "Promoter specific chromatin binding", "Protease binding", "Proteasome activating activity", "Proteasome binding", "Protein adp ribosylase activity", "Protein antigen binding", "Protein arginine n methyltransferase activity", "Protein arginine omega n asymmetric methyltransferase activity", "Protein arginine omega n monomethyltransferase activity", "Protein binding involved in heterotypic cell cell adhesion", "Protein c terminus binding", "Protein carboxyl o methyltransferase activity", "Protein carrier chaperone", "Protein containing complex binding", "Protein deacetylase activity", "Protein demethylase activity", "Protein dimerization activity", "Protein disaggregase activity", "Protein disulfide isomerase activity", "Protein disulfide reductase nad p activity", "Protein domain specific binding", "Protein folding chaperone", "Protein geranylgeranyltransferase activity", "Protein heterodimerization activity", "Protein homodimerization activity", "Protein hormone receptor activity", "Protein kinase a binding", "Protein kinase a catalytic subunit binding", "Protein kinase a regulatory subunit binding", "Protein kinase activity", "Protein kinase b binding", "Protein kinase c activity", "Protein kinase c binding", "Protein lipid complex binding", "Protein macromolecule adaptor activity", "Protein membrane adaptor activity", "Protein methyltransferase activity", "Protein n terminus binding", "Protein phosphatase 1 binding", "Protein phosphatase 2a binding", "Protein phosphatase activator activity", "Protein phosphatase binding", "Protein phosphatase regulator activity", "Protein phosphorylated amino acid binding", "Protein prenyltransferase activity", "Protein self association", "Protein sequestering activity", "Protein serine kinase activity", "Protein serine threonine kinase activator activity", "Protein serine threonine kinase activity", "Protein serine threonine kinase inhibitor activity", "Protein serine threonine phosphatase activity", "Protein serine threonine phosphatase inhibitor activity", "Protein serine threonine tyrosine kinase activity", "Protein tag", "Protein transmembrane transporter activity", "Protein transporter activity", "Protein tyrosine kinase activator activity", "Protein tyrosine kinase activity", "Protein tyrosine kinase binding", "Protein tyrosine kinase inhibitor activity", "Protein tyrosine phosphatase activity", "Protein tyrosine serine threonine phosphatase activity", "Protein tyrosine threonine phosphatase activity", "Proteoglycan binding", "Proton channel activity", "Proton transmembrane transporter activity", "Proton transporting atp synthase activity rotational mechanism", "Pseudouridine synthase activity", "Purine nucleotide transmembrane transporter activity", "Pyrimidine nucleotide binding", "Pyrimidine nucleotide sugar transmembrane transporter activity", "Pyrophosphate hydrolysis driven proton transmembrane transporter activity", "Pyruvate dehydrogenase acetyl transferring kinase activity", "Pyruvate dehydrogenase activity", "Pyruvate transmembrane transporter activity", "Quaternary ammonium group binding", "Quaternary ammonium group transmembrane transporter activity", "Quinone binding", "R smad binding", "Racemase and epimerase activity", "Racemase and epimerase activity acting on carbohydrates and derivatives", "Rage receptor binding", "Rdna binding", "Receptor antagonist activity", "Receptor tyrosine kinase binding", "Regulatory rna binding", "Retinal binding", "Retinal dehydrogenase activity", "Retinoic acid binding", "Retinoic acid receptor binding", "Retinoid x receptor binding", "Retromer complex binding", "Ribonuclease activity", "Ribonuclease p activity", "Ribonuclease p rna binding", "Ribonucleoprotein complex binding", "Ribonucleotide binding", "Ribose phosphate diphosphokinase activity", "Ribosomal large subunit binding", "Ribosomal protein s6 kinase activity", "Ribosomal small subunit binding", "Ribosome binding", "Rna 2 o methyltransferase activity", "Rna 7 methylguanosine cap binding", "Rna adenylyltransferase activity", "Rna binding", "Rna binding involved in posttranscriptional gene silencing", "Rna cap binding", "Rna directed dna polymerase activity", "Rna dna hybrid ribonuclease activity", "Rna methyltransferase activity", "Rna polymerase activity", "Rna polymerase binding", "Rna polymerase core enzyme binding", "Rna polymerase i general transcription initiation factor activity", "Rna polymerase i transcription regulatory region sequence specific dna binding", "Rna polymerase ii activity", "Rna polymerase ii c terminal domain binding", "Rna polymerase ii c terminal domain phosphoserine binding", "Rna polymerase ii core promoter sequence specific dna binding", "Rna polymerase ii ctd heptapeptide repeat kinase activity", "Rna polymerase ii ctd heptapeptide repeat phosphatase activity", "Rna polymerase ii general transcription initiation factor activity", "Rna polymerase ii general transcription initiation factor binding", "Rna polymerase ii specific dna binding transcription factor binding", "Rna polymerase iii transcription regulatory region sequence specific dna binding", "Rna stem loop binding", "Rna strand annealing activity", "Roundabout binding", "Rrna adenine methyltransferase activity", "Rrna binding", "Rrna cytosine methyltransferase activity", "S acyltransferase activity", "S adenosyl l methionine binding", "S adenosylmethionine dependent methyltransferase activity", "S methyltransferase activity", "S100 protein binding", "Salt transmembrane transporter activity", "Scaffold protein binding", "Scavenger receptor activity", "Secondary active transmembrane transporter activity", "Selenium binding", "Semaphorin receptor activity", "Sequence specific dna binding", "Sequence specific mrna binding", "Sequence specific single stranded dna binding", "Serine hydrolase activity", "Serine transmembrane transporter activity", "Serine type carboxypeptidase activity", "Serine type endopeptidase inhibitor activity", "Serine type exopeptidase activity", "Sh2 domain binding", "Sh3 domain binding", "Signal recognition particle binding", "Signal sequence binding", "Signaling adaptor activity", "Signaling receptor binding", "Signaling receptor complex adaptor activity", "Signaling receptor inhibitor activity", "Signaling receptor regulator activity", "Single stranded dna 3 5 exodeoxyribonuclease activity", "Single stranded dna binding", "Single stranded dna endodeoxyribonuclease activity", "Single stranded dna exodeoxyribonuclease activity", "Single stranded dna helicase activity", "Single stranded rna binding", "Single stranded telomeric dna binding", "Sirna binding", "Smad binding", "Small molecule sensor activity", "Small protein activating enzyme binding", "Small ribosomal subunit rrna binding", "Snap receptor activity", "Snare binding", "Snorna binding", "Snrna binding", "Snrnp binding", "Sodium channel inhibitor activity", "Sodium channel regulator activity", "Sodium chloride symporter activity", "Sodium ion binding", "Sodium ion transmembrane transporter activity", "Solute anion antiporter activity", "Solute cation antiporter activity", "Solute cation symporter activity", "Solute proton antiporter activity", "Solute proton symporter activity", "Solute sodium symporter activity", "Spectrin binding", "Sphingolipid binding", "Sphingolipid transfer activity", "Sphingolipid transporter activity", "Sphingomyelin phosphodiesterase activity", "Sphingosine 1 phosphate receptor activity", "Sphingosine n acyltransferase activity", "Steroid binding", "Steroid dehydrogenase activity", "Steroid dehydrogenase activity acting on the ch oh group of donors nad or nadp as acceptor", "Steroid hormone binding", "Steroid hormone receptor activity", "Sterol binding", "Sterol esterase activity", "Sterol transfer activity", "Sterol transporter activity", "Structural constituent of cytoskeleton", "Structural constituent of eye lens", "Structural constituent of muscle", "Structural constituent of nuclear pore", "Structural constituent of postsynapse", "Structural constituent of postsynaptic actin cytoskeleton", "Structural constituent of presynaptic active zone", "Structural constituent of ribosome", "Structural constituent of synapse", "Structural molecule activity", "Structural molecule activity conferring elasticity", "Succinate transmembrane transporter activity", "Sulfate binding", "Sulfate transmembrane transporter activity", "Sulfatide binding", "Sulfotransferase activity", "Sulfur compound binding", "Sulfur compound transmembrane transporter activity", "Sulfuric ester hydrolase activity", "Sulfurtransferase activity", "Sumo binding", "Sumo ligase activity", "Sumo specific protease activity", "Sumo transferase activity", "Supercoiled dna binding", "Superoxide dismutase activity", "Superoxide generating nadph oxidase activator activity", "Symporter activity", "Syndecan binding", "Syntaxin 1 binding", "Syntaxin binding", "T cell receptor binding", "Tap binding", "Tap1 binding", "Tat protein binding", "Tau protein binding", "Tau protein kinase activity", "Tbp class protein binding", "Telomerase activity", "Telomerase inhibitor activity", "Telomerase rna binding", "Telomeric dna binding", "Testosterone dehydrogenase nad p activity", "Testosterone dehydrogenase nadplus activity", "Tetrapyrrole binding", "Tfiib class transcription factor binding", "Tfiid class transcription factor complex binding", "Thiamine pyrophosphate binding", "Thioesterase binding", "Thiol oxidase activity", "Thiolester hydrolase activity", "Thioredoxin disulfide reductase activity", "Threonine type endopeptidase activity", "Threonine type peptidase activity", "Thyroid hormone receptor binding", "Titin binding", "Toll like receptor binding", "Toxic substance binding", "Tpr domain binding", "Transcription coactivator activity", "Transcription coactivator binding", "Transcription coregulator activity", "Transcription coregulator binding", "Transcription corepressor activity", "Transcription corepressor binding", "Transcription elongation regulator activity", "Transcription factor binding", "Transcription regulator activity", "Transcription regulator inhibitor activity", "Transferase activity transferring alkyl or aryl other than methyl groups", "Transferase activity transferring nitrogenous groups", "Transferase activity transferring one carbon groups", "Transferase activity transferring phosphorus containing groups", "Transferase activity transferring sulphur containing groups", "Transferrin receptor binding", "Transforming growth factor beta receptor binding", "Transition metal ion binding", "Transition metal ion transmembrane transporter activity", "Transketolase or transaldolase activity", "Translation activator activity", "Translation elongation factor activity", "Translation factor activity rna binding", "Translation initiation factor activity", "Translation initiation factor binding", "Translation regulator activity", "Translation regulator activity nucleic acid binding", "Translation repressor activity", "Translation repressor activity mrna regulatory element binding", "Translation termination factor activity", "Transmembrane receptor protein kinase activity", "Transmembrane receptor protein phosphatase activity", "Transmembrane receptor protein tyrosine kinase activity", "Transmembrane transporter binding", "Transporter activity", "Tripeptide transmembrane transporter activity", "Trna binding", "Trna cytosine methyltransferase activity", "Trna guanine methyltransferase activity", "Trna methyltransferase activity", "Trna specific adenosine deaminase activity", "Trna specific ribonuclease activity", "Tropomyosin binding", "Tubulin binding", "Tumor necrosis factor activated receptor activity", "Tumor necrosis factor receptor binding", "Tumor necrosis factor receptor superfamily binding", "Type 1 fibroblast growth factor receptor binding", "Type i transforming growth factor beta receptor binding", "U1 snrna binding", "U2 snrna binding", "U3 snorna binding", "U4 snrna binding", "U6 snrna binding", "Ubiquinol cytochrome c reductase activity", "Ubiquinone binding", "Ubiquitin binding", "Ubiquitin conjugating enzyme binding", "Ubiquitin ligase substrate adaptor activity", "Ubiquitin like modifier activating enzyme activity", "Ubiquitin like protein binding", "Ubiquitin like protein conjugating enzyme activity", "Ubiquitin like protein conjugating enzyme binding", "Ubiquitin like protein ligase activity", "Ubiquitin like protein ligase binding", "Ubiquitin like protein specific isopeptidase activity", "Ubiquitin like protein specific protease activity", "Ubiquitin like protein transferase activity", "Ubiquitin protein transferase activator activity", "Ubiquitin protein transferase inhibitor activity", "Ubiquitin protein transferase regulator activity", "Ubiquitin specific protease binding", "Ubiquitin ubiquitin ligase activity", "Ubiquitination like modification dependent protein binding", "Udp galactose beta n acetylglucosamine beta 1 3 galactosyltransferase activity", "Udp glucosyltransferase activity", "Udp glycosyltransferase activity", "Udp xylosyltransferase activity", "Unfolded protein binding", "Unmethylated cpg binding", "Uridylyltransferase activity", "Vascular endothelial growth factor receptor 2 binding", "Vascular endothelial growth factor receptor binding", "Very long chain fatty acid coa ligase activity", "Vinculin binding", "Virion binding", "Vitamin b6 binding", "Vitamin binding", "Vitamin d binding", "Vitamin d receptor binding", "Vitamin transmembrane transporter activity", "Voltage gated anion channel activity", "Voltage gated calcium channel activity", "Voltage gated calcium channel activity involved in regulation of cytosolic calcium levels", "Voltage gated cation channel activity", "Voltage gated channel activity", "Voltage gated chloride channel activity", "Volume sensitive anion channel activity", "Water channel activity", "Water transmembrane transporter activity", "Wd40 repeat domain binding", "Wide pore channel activity", "Ww domain binding", "Xenobiotic transmembrane transporter activity", "Y form dna binding", "Zinc ion binding"], "available_proteins": ["AACS", "AAK1", "AAMP", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD6", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ADA", "ADAM17", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKT1", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG13", "ALG5", "ALKBH1", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC2", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "APC", "APEH", "APEX1", "API5", "APMAP", "APOBEC3C", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP3", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGAP35", "ARHGAP5", "ARHGDIA", "ARHGEF2", "ARID1A", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL8B", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARVCF", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATE1", "ATF7IP", "ATG3", "ATG4B", "ATG9A", "ATIC", "ATL2", "ATL3", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPIF1", "ATRX", "ATXN2", "ATXN2L", "AUP1", "B3GALT6", "B4GALT1", "B4GAT1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BCAP31", "BCAT2", "BCCIP", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BDH2", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOD1L1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAP", "BRCA1", "BRD2", "BRD4", "BRIX1", "BSG", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C1QBP", "C1orf123", "C1orf35", "C1orf50", "C20orf27", "C2CD5", "CAB39", "CACTIN", "CACUL1", "CACYBP", "CAD", "CADM1", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAP2", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CASK", "CASP2", "CASP3", "CAST", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC124", "CCDC22", "CCDC47", "CCDC51", "CCDC6", "CCDC86", "CCDC88A", "CCNA2", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC23", "CDC25C", "CDC27", "CDC37", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP3", "CDK6", "CDKAL1", "CDKN2A", "CDKN2AIP", "CDR2L", "CDS2", "CDX2", "CEBPZ", "CECR2", "CELF1", "CENPB", "CENPE", "CENPV", "CEP250", "CEP44", "CEP55", "CERS2", "CETN2", "CFAP20", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHCHD4", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP4A", "CHMP4B", "CHMP5", "CHORDC1", "CHP1", "CHRAC1", "CHST14", "CHTF18", "CHTF8", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CIZ1", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLN6", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLSPN", "CLTA", "CLTC", "CLU", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNOT1", "CNOT7", "CNOT9", "CNP", "COASY", "COG2", "COIL", "COLEC12", "COLGALT1", "COMMD1", "COMMD7", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS4", "COPS5", "COPS6", "COQ8A", "CORO1B", "CORO1C", "COTL1", "COX11", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7A2L", "CPD", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTDSPL2", "CTH", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CTTNBP2NL", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC22", "CWF19L1", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF7", "DCAKD", "DCD", "DCP1A", "DCP1B", "DCP2", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENND4C", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHODH", "DHPS", "DHRS1", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DIS3L2", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTL", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EDC3", "EDF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFL1", "EFTUD2", "EGFR", "EGLN1", "EHD1", "EHD4", "EHMT2", "EIF2A", "EIF2AK2", "EIF2AK4", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELOB", "ELOC", "ELP1", "ELP2", "ELP4", "EMC1", "EMC2", "EMC3", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENSA", "EPB41", "EPB41L2", "EPB41L5", "EPDR1", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC3", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXTL3", "EZR", "F11R", "FABP5", "FAF1", "FAF2", "FAHD1", "FAM118B", "FAM208A", "FAM213A", "FAM49B", "FAM50A", "FAM83D", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FAU", "FBL", "FBXO22", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FMR1", "FNDC3A", "FNTA", "FNTB", "FOXRED1", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCLM", "GCN1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGCT", "GGCX", "GGH", "GGT7", "GHDC", "GID4", "GID8", "GIGYF2", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNE", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLPH3", "GOLPH3L", "GOPC", "GOT1", "GOT2", "GPAM", "GPATCH4", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR89B", "GPS1", "GPSM1", "GPT2", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSDME", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C4", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTSE1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAGH", "HARS2", "HAT1", "HAUS4", "HAUS6", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDGFL2", "HDHD2", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HELLS", "HERC4", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOXD13", "HP1BP3", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA6", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFNGR1", "IFT27", "IFT88", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBKB", "IKBKG", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPA1", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS11", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRGQ", "IRS4", "ISCU", "ISG20L2", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITSN2", "IVD", "JMJD6", "JUP", "KARS", "KAT7", "KCTD12", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0368", "KIAA0391", "KIF11", "KIF14", "KIF15", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KMT2A", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "L2HGDH", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCMT1", "LDHA", "LDHB", "LDLR", "LDLRAP1", "LEMD2", "LEMD3", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRP1", "LRPAP1", "LRPPRC", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRWD1", "LSM14A", "LSM14B", "LSM2", "LSM6", "LSS", "LTA4H", "LTN1", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYPLAL1", "LZIC", "LZTFL1", "M6PR", "MACF1", "MAD1L1", "MAGED1", "MAGT1", "MAIP1", "MAK16", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K3", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARK1", "MARK2", "MARS", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MED1", "MED14", "MED16", "MED21", "MED23", "MED24", "MED4", "MEPCE", "METAP1", "METAP2", "METTL1", "METTL13", "METTL16", "METTL3", "MFAP1", "MFF", "MFN1", "MFN2", "MFSD10", "MFSD5", "MGAT1", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA3", "MICALL1", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MKLN1", "MKRN2", "MLEC", "MMAB", "MMGT1", "MMS19", "MOGS", "MORC2", "MORF4L1", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP7", "MPRIP", "MPST", "MRC2", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL22", "MRPL23", "MRPL28", "MRPL3", "MRPL37", "MRPL39", "MRPL4", "MRPL40", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL55", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTDH", "MTERF3", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR2", "MTOR", "MTPAP", "MTR", "MTSS1L", "MUT", "MVK", "MYBBP1A", "MYCBP", "MYCBP2", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA16", "NAA40", "NAA50", "NACC1", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCKAP1", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "ND5", "NDC1", "NDC80", "NDUFA10", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEFL", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NFKB1", "NFS1", "NFU1", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NISCH", "NIT2", "NKRF", "NKTR", "NLN", "NMD3", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSUN2", "NSUN5", "NSUN6", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP35", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NVL", "NXF1", "NXN", "OAT", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1", "PAK2", "PAK4", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNT", "PCYOX1", "PDAP1", "PDCD11", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDPR", "PDXDC1", "PDXK", "PDZD8", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN1", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGGT1B", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PI4KB", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGL", "PIH1D1", "PIK3C2A", "PIK3C3", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2B", "PIR", "PISD", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCB3", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNISR", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPO", "PNPT1", "POFUT1", "POLA1", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKAR2B", "PRKCD", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA3", "PSMA4", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN23", "PTPN9", "PTPRF", "PTRH2", "PTRHD1", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "PYM1", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABEP1", "RABGAP1", "RABGGTA", "RABGGTB", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RANGRF", "RAP1GDS1", "RAPGEF2", "RAPGEF6", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM47", "RBM5", "RBM8A", "RBMX", "RBPMS", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "RECQL5", "REEP3", "REEP4", "REPS1", "RER1", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIOX1", "RIOX2", "RIPK1", "RMDN1", "RMND5A", "RNASEH2A", "RNASET2", "RNF14", "RNF20", "RNF219", "RNF220", "RNF40", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RPUSD2", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP12", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RTCA", "RTCB", "RTF1", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SACS", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAP18", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SBNO1", "SCAF1", "SCAF11", "SCAF4", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCYL2", "SDCBP", "SDF2L1", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD7", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL", "SH3BGRL2", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIN3A", "SIRT1", "SKA1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC30A7", "SLC35A4", "SLC35B2", "SLC35F2", "SLC38A2", "SLC3A2", "SLC4A1AP", "SLC6A15", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SLU7", "SMAP1", "SMAP2", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SNAP23", "SNAP29", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC24", "SPCS2", "SPDL1", "SPEN", "SPHK2", "SPNS1", "SPOUT1", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRBD1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX4", "STX6", "STX7", "STX8", "STXBP2", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYNCRIP", "SYNE1", "SYNE2", "TAB1", "TACO1", "TADA3", "TAF15", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D17", "TBC1D2B", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCA", "TBCC", "TBCD", "TBCE", "TBK1", "TBL1XR1", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TDRD7", "TDRKH", "TECR", "TELO2", "TERF2", "TERF2IP", "TES", "TEX264", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFRC", "TGS1", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM17A", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TIMM9", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLN1", "TMCO1", "TMED10", "TMED9", "TMEM109", "TMEM165", "TMEM192", "TMEM201", "TMEM206", "TMEM30A", "TMEM43", "TMEM59", "TMEM63A", "TMF1", "TMLHE", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOM1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPMT", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIO", "TRIP12", "TRIP13", "TRIR", "TRMT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMU", "TROVE2", "TRUB1", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPO", "TSPYL1", "TSR1", "TTC1", "TTC26", "TTC28", "TTC4", "TTF2", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXN2", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2", "UBAP2L", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE2T", "UBE3A", "UBE3C", "UBE4A", "UBL5", "UBLCP1", "UBP1", "UBQLN1", "UBQLN2", "UBQLN4", "UBR1", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "UHRF1BP1", "UMPS", "UNC119B", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRC1", "UQCRC2", "UQCRFS1", "URB1", "UROD", "USO1", "USP10", "USP11", "USP14", "USP15", "USP24", "USP28", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "UXT", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VPS18", "VPS25", "VPS33B", "VPS35", "VPS37C", "VPS4A", "VPS4B", "VRK1", "VRK2", "VTA1", "VTI1B", "WARS", "WARS2", "WASL", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR3", "WDR36", "WDR4", "WDR41", "WDR43", "WDR45B", "WDR46", "WDR48", "WDR5", "WDR6", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WNK1", "WNK2", "WRAP53", "WTAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YAP1", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", 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"HIP1", "HK2", "HLA-A", "HLA-C", "HMCES", "HMGB2", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HPS6", "HS2ST1", "HSD17B12", "HSDL1", "HSP90AA1", "HSP90AB1", "HSPA8", "HTT", "ICMT", "IDH1", "IDH2", "IFNGR1", "IGF2R", "IPO11", "IPO4", "IQGAP2", "KDELR1", "KDELR3", "KDM1B", "KDSR", "KHSRP", "KIF14", "KMT2A", "KPNA4", "LAMC1", "LARP1", "LBR", "LDLRAP1", "LETM1", "LMAN1", "LMAN2", "LNPEP", "LPCAT1", "LPGAT1", "LRPAP1", "LSS", "LTA4H", "M6PR", "MAIP1", "MAN1A2", "MAPK1", "MAPK14", "MBOAT7", "MGAT1", "MGEA5", "MGST3", "MIF", "MINDY3", "MIPEP", "MLEC", "MMGT1", "MOGS", "MPC2", "MRC2", "MRPS11", "MRPS18A", "MSI1", "MSMO1", "MTAP", "MYO18A", "NAA10", "NAA15", "NAA40", "NAGLU", "NAMPT", "NCLN", "NDUFB1", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS2", "NEFL", "NENF", "NES", "NISCH", "NLN", "NNT", "NPC1", "NPC2", "NPEPPS", "NPTN", "NSD2", "NSUN2", "NT5C3A", "NT5C3B", "NTMT1", "NUCB1", "NUCB2", "NUDT12", "NUDT5", "NUP62", "NUPL2", "NXN", "OLA1", "OPA1", "OSBPL3", "OTUB1", "OXA1L", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PABPC1", "PABPC4", "PAIP1", "PALLD", "PCMT1", "PCYOX1", "PDCD5", "PDCD6", "PDCL3", "PDE6D", "PDLIM3", "PDLIM5", "PDLIM7", "PEBP1", "PECR", "PELP1", "PEX5", "PFDN1", "PFDN2", "PGGT1B", "PGRMC1", "PGRMC2", "PHF2", "PI4KA", "PIR", "PITRM1", "PKM", "PLA2G15", "PLAA", "PLD3", "PPAT", "PPME1", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPT1", "PPT2", "PRCP", "PRDX3", "PREP", "PREPL", "PRMT1", "PRMT9", "PRPF8", "PSAP", "PSMA1", "PSMA6", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMD14", "PSMD7", "PTGES3", "PTPRF", "PUS7", "PYM1", "QSOX2", "RAB34", "RAB5B", "RACK1", "RAD23A", "RALA", "RAN", "RANGRF", "RBM10", "RBM4", "RBPMS", "RCN2", "RDH11", "RDH13", "RDH14", "REPS1", "RIOX1", "RIPK1", "RNF14", "RNF20", "RPS3", "RRM2B", "S100A13", "SCARB1", "SCARB2", "SCCPDH", "SCO1", "SCPEP1", "SEC11A", "SET", "SFXN2", "SFXN4", "SGPL1", "SHMT1", "SHMT2", "SIGMAR1", "SLC12A2", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A10", 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41.19660194174757 0.3636351001240374 0.5903090665886829 4.629439374954948 2.5633125009393525 0.8124485448597606 0.3243501761394795 0.0002930628984939 0.0056332205677222 0.0007394374554927 0.0338869207736729 0.0687640723159954 +Hypoplasia of the uterus 1 9 2.2529876962358 0.0242599247549548 2.5558252427184467 9.067961165048544 0.1608182616470751 0.5445262331102442 2.0227564698821716 0.8448833540714317 0.8729968156041269 0.290854883922868 0.1475747309757272 0.0937235599037543 0.1774332758731671 0.0840389641709933 0.255405515221392 +Skin nodule 9 24 2.252274387579386 0.0243049376791641 6.070388349514563 21.26456310679612 0.7442674094202993 0.3924071478475022 2.7239314899251803 2.029014432281319 1.0984628042075235 0.3129154853478004 0.0892654513631074 0.2670314735990955 0.0231701844530087 0.0182889167317254 0.0008733527805083 +Wormian bones 4 16 2.2481682639070675 0.0245654625191324 4.580097087378641 17.57766990291262 0.8294573681393818 0.4043540785232756 2.1077508350863132 1.8331590876272783 0.898450188873912 0.3090371568059936 0.0280716481522621 0.0112943240362007 0.0405463165390607 0.0011115841037105 0.0047299686256361 +Increased susceptibility to fractures 9 53 2.24424818909596 0.0248164370733279 11.298543689320388 52.63834951456311 0.6062165983596748 0.5457625999772061 4.708049068828723 5.888757199406996 0.818710666746425 0.3467528628559314 0.0060222782687641 0.0055769350519062 0.0029242198848194 0.0029629033957542 0.0535155053292243 +Abnormal cranial nerve physiology 21 73 2.2355794115992498 0.0253793344686921 15.28640776699029 70.41019417475728 0.3474177643184146 0.6276590204132638 5.1247078731555415 8.772153257771443 0.7667367226441726 0.3323095327727143 0.2715884517931861 0.3081504582131807 0.1808069875135375 0.1045213172312255 0.0017534467540442 +Micromelia 6 23 2.231930648165404 0.0256195469085038 5.094660194174757 22.143203883495147 0.8629445430209934 0.441515711810184 2.300964472974588 2.4557002100293746 0.9703688762337884 0.333324080713348 0.0023988011755242 0.0050180872027471 0.0049422249763305 0.0290193936755207 0.0218760297012545 +Bilateral cryptorchidism 1 10 2.224804413354588 0.0260943710035717 2.6529126213592233 9.849514563106796 0.7102983026891413 0.4046694096755988 1.7935743620951357 1.043553840834269 0.9852608840174656 0.3101013475492273 0.0153631225051974 0.1114073342812727 0.0224191931510111 0.1147066696002357 0.1098061730973064 +Open mouth 5 33 2.220024774999516 0.026417085895978 7.077669902912621 30.00242718446602 0.3202486237599461 0.655106586474338 3.66944698457265 3.258669382986025 0.6877613332231043 0.3051225284180853 0.5058485752328652 0.3523884632837075 0.5778229381468787 0.0201301952667497 0.1379525018897012 +Abnormal peripheral nervous system physiology 15 59 2.2081135293577367 0.0272363601186973 11.83252427184466 51.817961165048544 0.7177191808834937 0.5138073353423627 5.464680098551787 6.244482435854531 0.8794747687270434 0.3477667568343747 0.2409871609200163 0.1137743690382112 0.1070377409089595 0.0005893352974441 1.531703615657299e-05 +Abnormality of neutrophil morphology 1 5 2.202457905749992 0.0276329794296099 1.3495145631067962 5.186893203883495 0.8052558850098389 0.4007759928981252 1.1613411887055554 0.6730044635900011 0.8443305889492255 0.2973774449831792 0.0021644162661245 0.0432957136582515 0.0032139762811053 0.0189506401306209 0.0682492372420068 +Knee flexion contracture 7 27 2.2013563522935966 0.0277108064000697 6.37621359223301 26.20631067961165 0.4874196163722039 0.571576100604669 2.548884628142718 2.167424085317431 0.796597726565237 0.3234136220769761 0.0130510720508035 0.0369748680428621 0.0222198796395938 0.0637468602571873 0.0101560616848899 +Contractures of the joints of the upper limbs 14 79 2.1929750374069505 0.0283091776579 15.5873786407767 70.82038834951456 0.961917368584866 0.453560490665382 5.296970733704175 9.19591360516456 0.9682537043334576 0.378553967263451 0.0081463397510421 0.0043835120706257 0.0056363395109051 0.0077694901046194 0.0230651028820117 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0.0298008594609224 1.7985436893203883 7.135922330097087 0.8897551200199579 0.2742817695009352 1.2050451450005106 0.7670210145007976 1.1859557261264115 0.267107203595487 0.1475747309757272 0.0937235599037543 0.1774332758731671 0.0119341177484456 0.0145952588649919 +Abnormal full field electroretinogram 3 8 2.172727145266322 0.0298008594609224 1.7985436893203883 7.135922330097087 0.8897551200199579 0.2742817695009352 1.2050451450005106 0.7670210145007976 1.1859557261264115 0.267107203595487 0.1743971944450219 0.1114073342812727 0.208984012191681 0.0197332243190265 0.0274602362801676 +Increased cerebral lipofuscin 2 6 2.16371838455878 0.0304859691659609 3.0970873786407767 5.118932038834951 1.0434065701738664 0.1270836154757583 1.1278862704044743 0.4599818751628888 1.7720117842909846 0.2267161680252343 0.0766948790541844 1.0 0.0930016660897952 0.0015031185668187 0.0107435842434709 +Ragged red muscle fibers 9 19 2.1514467069075423 0.0314409579707899 5.233009708737864 17.730582524271846 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3.372723692373783 0.977277602505203 0.3249512351298445 0.3076834968085814 0.2027885470531376 0.3622612502953293 0.0008076868843539 5.8677187288410415e-05 +Abnormal epiphyseal ossification 4 17 2.1030025275224307 0.0354655485496013 6.451456310679611 16.274271844660195 1.1227269321938518 0.3276999393402902 3.140724178369711 2.4155680760400804 1.043634905787503 0.3148370578580727 0.0475672289294156 0.0195557545343205 0.0678620701894922 0.0040949780430722 0.061872997913683 +Mucosal telangiectasiae 3 9 2.0851378315161475 0.0370567910816175 3.2354368932038833 9.689320388349516 0.8501086222195428 0.291727970426265 1.410916714116348 1.5996305775803197 1.2598794700933909 0.2907637890882055 0.2003857556648621 0.1287528218161406 0.0299460957191466 0.0044180066438726 0.0105347068278647 +Hypoketotic hypoglycemia 2 7 2.084054489682119 0.0371552110848207 2.3470873786407767 7.560679611650485 1.365087782487965 0.212332843161917 1.4324316558480732 0.6923349575659244 0.8002406012991511 0.2265642620801705 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4.685854213547734 5.0957713280196595 0.8793305042203639 0.3427211662973412 0.0728761287227332 0.1201931014379405 0.1152579533053658 0.0007657984630376 1.649780952479872e-06 +Goiter 4 9 2.029042868031442 0.0424539242099966 2.6844660194174756 8.25242718446602 0.6101001322888668 0.361705743263382 1.3785638567356056 1.7624367872817217 1.1902904119866486 0.3002320766724904 0.0249751327445929 0.141543756104335 0.0361556764775263 0.0064140084647031 0.016158457458282 +Eeg with focal spikes 1 5 2.026317574880025 0.0427322513960297 1.199029126213592 4.611650485436893 0.2009379318587673 0.3945439266933198 1.2224434504069814 1.009498671202671 1.1758184518685515 0.2899583413391119 0.0766948790541844 1.0 0.0930016660897952 0.0233125205204954 0.0826256504885364 +Neoplasm of the adrenal gland 2 14 2.022907487423194 0.0430826864575251 3.599514563106796 12.655339805825244 -0.0229147935388063 0.4774880458026877 2.388747845463265 1.625836791588109 1.1093825108151067 0.3217315950535707 0.0296748446689961 0.1541506060207377 0.0428134756181982 0.0489147892655661 0.229933672353323 +Abnormal auditory evoked potentials 3 10 2.022858809636688 0.0430877063239669 2.837378640776699 8.45388349514563 0.8113355275163785 0.2966376606156203 1.5470802196866602 1.3128600166506037 1.1722229382642326 0.2813987538538041 1.0 1.0 1.0 0.0119341177484456 0.0145952588649919 +Coxa vara 6 15 2.021140377826615 0.0432652355527278 4.310679611650485 13.54126213592233 0.853738655548226 0.4218003203060939 1.9720332330132235 1.9928869528934432 0.8140335419312188 0.3116542205645756 0.0418618910852873 0.0171096007657598 0.0599227725053796 0.0170966332614883 0.0138285747900004 +Increased bone mineral density 5 25 2.019632820305956 0.0434214881668038 6.242718446601942 24.75 1.1480702818250033 0.3148175930983396 2.4533156459354677 2.2345749579547443 1.0849696139569316 0.312718333498069 0.1221149024095898 0.0533785743764077 0.0375044006736284 0.0103112949664871 0.1662081916388383 +Abnormal enchondral ossification 6 30 2.0166706065018603 0.0437298993109087 8.825242718446601 28.097087378640776 0.9354465670440578 0.4238671948965085 3.7994051258084856 4.343870948544361 0.9586864854575652 0.3408490652683477 0.0308583270045627 0.0085356676981486 0.0509823499368979 0.0048612051814509 0.0583899255599222 +Psychomotor deterioration 3 10 2.013210999685685 0.0440924365429298 3.2645631067961167 8.910194174757281 0.9753014938956188 0.1960965459818884 1.3866235282600423 0.7031088807706056 1.4929387846379636 0.2609606457365817 1.0 1.0 1.0 0.0002054625318554 0.0028246814840344 +Limb tremor 0 6 2.009664231539949 0.0444667380680272 1.3349514563106797 5.432038834951456 0.3555843582242272 0.4821359095354677 1.1984787070431178 1.0229135612707716 0.9441619507872608 0.2886202782468935 0.0766948790541844 0.0479914252810258 0.0930016660897952 0.2183511668733661 0.3940663935801297 +Aplasia hypoplasia of the patella 1 6 2.008515663905124 0.044588523228827 1.5218446601941749 5.584951456310679 0.5626147938318666 0.4502183820300943 1.1913965433231544 1.2828467840821514 0.9140365060117206 0.2971205043347708 0.0141550959339492 0.0055832614279084 0.0206800818926893 0.1067922158236129 0.3106281566010752 +Aplasia hypoplasia involving the vertebral column 3 16 2.008207903305577 0.0446212035252016 4.679611650485437 14.847087378640778 0.8883735186508074 0.3527358077962234 2.3127489306396716 2.051146083169333 0.9597872998017484 0.2871451112966173 0.0456351184097705 0.0187248462666395 0.0651781855152293 0.0200675030127402 0.1566651346062924 +Slowly progressive 11 58 2.0018205260090234 0.0453040375392426 12.696601941747574 56.12378640776699 0.7411325364412068 0.522622208333598 5.310978564028389 4.912508033345017 0.8104226905999934 0.3549765630745758 0.2675331714822004 0.4664619130311752 0.1258579604603527 0.0352683688206443 0.0035585791441829 +Neonatal hypoglycemia 2 10 2.001247845824168 0.0453656871280021 2.237864077669903 10.04368932038835 0.7747126119899399 0.4306543785319578 1.853027777096223 1.7524002902489448 0.8324785090654103 0.3000381254726006 0.1874940936179018 0.1201219647894398 0.2243071172363204 0.1309570889500886 0.1315350963393062 +Positive romberg sign 4 9 1.9902867381255895 0.0465593580684431 2.466019417475728 8.308252427184467 1.0733671875840938 0.3096488241780741 1.4485716699970723 1.6764009803624336 0.8283755892460324 0.2651507773538893 0.1128336603904996 1.0 0.1362380906066266 0.050241067872642 0.000543833852376 +Biliary tract abnormality 7 26 1.9837918317733203 0.0472790511029128 8.184466019417476 26.4004854368932 1.3038634098573934 0.2674323053300255 3.1080777089644696 2.335313487465734 1.3483489456318312 0.3101233364725878 0.0916863952751726 0.270648213584465 0.1279708837725801 0.019457743384681 0.0122183370484826 +Abnormality of skull ossification 3 12 1.982781951927604 0.0473917908413319 4.366504854368932 12.970873786407768 1.1881205011944458 0.2637442069575459 1.99249670608582 1.4511884027191762 0.8848235988748787 0.2626440236811827 0.0296748446689961 0.0119629297909749 0.0428134756181982 0.0489147892655661 0.0821355875685036 +Cogwheel rigidity 2 7 1.980665806369748 0.047628763793017 1.691747572815534 5.41747572815534 0.5245835815764137 0.3763230502268936 1.2788913032023987 1.4212279105346624 1.148580263275354 0.3055796210169491 0.1198919526526125 0.0756950383436983 0.144637307685789 0.0565188023636715 0.0403506671570748 +Aplasia hypoplasia of the sternum 2 5 1.9771986722504375 0.0480191776442817 1.133495145631068 4.012135922330097 0.5166630082494199 0.4850062350958844 0.9079713959160156 0.8374419562386456 0.909226173990482 0.3051090882313388 0.1057194663998679 0.066549445548378 0.1277572387780678 0.2917500038862815 0.0281854945142632 +Hand muscle weakness 4 13 1.973783781712404 0.048406333748574 2.8058252427184467 10.820388349514564 0.4952781372617184 0.5553355274479741 1.7253577224537426 1.6697688476326478 0.7717943987196815 0.3071851204356355 0.1809714991267609 0.1157751708195439 0.2166826538338764 0.4600796867443816 0.0064224361124591 +Abnormal lung lobation 8 16 1.9677210947152912 0.0491001373027528 3.266990291262136 13.402912621359222 0.8057824047211188 0.4237226990881645 1.8647412350490211 1.7258152040640289 0.8098324555644494 0.3032019531807652 0.231737725640336 0.1499686155438198 0.2756599666896902 0.0453869127531283 0.0008961412475066 +Respiratory arrest 1 9 1.9673636465935624 0.0491413022627935 2.0558252427184467 7.070388349514563 1.3186130117670736 0.2232983865916446 1.389730031946098 1.4320861436977392 0.8270726521635177 0.2287950263954721 0.0087823993506393 0.0847528009868792 0.012905013470629 0.0698282842903305 0.2186430557746356 +Scotoma 5 13 1.965756589362088 0.0493267345127639 4.189320388349515 12.196601941747574 1.1271039056750725 0.2779036999445621 2.1128553643245884 2.0698220238662226 1.1901076059375446 0.2884356618441315 0.2736002811127123 0.1788224008957527 0.3236452024265956 0.0157211013123339 0.0122973883017787 +Hypomimic face 4 11 1.9625138853897464 0.049702685621209 3.133495145631068 11.58495145631068 0.4421860712869992 0.5404834791734886 1.9218075071756353 2.5628160231505692 0.8181668401155788 0.2989202640149896 1.0 1.0 0.2318581098993339 0.0270423729706739 0.009006759688013 diff --git a/msigdb_hp/metrics.json b/msigdb_hp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..458f2d551ca6a384b993085df61c0f3ac69c64d6 --- /dev/null +++ b/msigdb_hp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3329, + "annotations_size": 4656, + "title": "Average number of proteins per term", + "value": 24.924183848797252 +} \ No newline at end of file diff --git a/msigdb_hp/paths.json b/msigdb_hp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..420428ee37a9dd6ed626b1715675913fa8b0c110 --- /dev/null +++ b/msigdb_hp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_hp/fragment/C342/C342_val_log2fc"} \ No newline at end of file diff --git a/msigdb_hp/result.tsv b/msigdb_hp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..bc66d5d72a45e93667147ea9d1a3c405fb0ab2a4 --- /dev/null +++ b/msigdb_hp/result.tsv @@ -0,0 +1,1562 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Incoordination 0.5302624987849314 2.8881894464028073 0.0038746642912079 0.999999985877235 0.376952763113645 78 Q9Y5P6,P11047,Q9Y619,P42858,P12235,Q01105,Q9NR77,Q15067,P07602,O95140,Q9UJX6,O75503,P00846,Q6DKK2,Q7RTS9,Q7LG56,P04062 17 +Frequent falls 0.5986422835136368 2.772285240607976 0.0055664236109305 0.999999999994838 0.376952763113645 43 Q9Y5P6,P11047,P12235,Q06210,Q9NR77,P07602,O95140,P00846,Q13510,O75340,Q7RTS9,Q7LG56,P04062 13 +Platyspondyly 0.6260840517025412 2.7592795474940797 0.0057928957335118 0.9999999999982124 0.376952763113645 37 Q32P28,O95831,O75874,Q96AY3,P48735,Q14739,Q7RTS9 7 +Disproportionate short stature 0.6794131037265084 2.735594646384341 0.0062267676813514 0.9999999999997656 0.376952763113645 25 Q15125,Q32P28,Q6DKJ4,O95613,Q03164,Q9UBM7,Q15392,Q7LGA3,O15228,O75718,Q9UHX1,O43909,Q14739,Q7RTS9 14 +Postural tremor 0.7160462235825252 2.70438916228231 0.0068430094572331 0.999999999999987 0.376952763113645 19 Q9H6K4,Q9NR77,O75306,P00846,O95140,Q14108,P35637 7 +Proportionate short stature 0.6220690889582267 2.661924696893321 0.0077695258004086 0.9999999999999998 0.376952763113645 35 P53701,Q9Y619,Q15392,P10619,Q14739,Q7RTS9 6 +Disproportionate short limb short stature 0.7016153269891533 2.6235448299090955 0.0087019992272774 1.0 0.376952763113645 19 Q15125,Q32P28,Q6DKJ4,Q03164,Q9UBM7,Q15392,Q7LGA3,O15228,O75718,Q14739,Q7RTS9 11 +Sensorimotor neuropathy 0.618050256507092 2.5716991005800787 0.0101200806248293 1.0 0.376952763113645 33 Q9Y2R0,Q9NSE4,O95831,Q9NR77,P07602,O60313,P41440,P00846,O15270,Q15120,Q7LG56,Q8N2K0 12 +Severe short stature 0.6592313759900984 2.5679673324434007 0.0102296795919487 1.0 0.3780110173024875 24 P10619,Q15392,Q7RTS9,Q9Y619 4 +Abnormal astrocyte morphology 0.6883071331233094 2.548250204433299 0.0108264790798617 1.0 0.3877545122756651 19 P00846,O95831,O75874,P48735 4 +Tinnitus 0.7512729585830704 2.535172568744368 0.0112391943850094 1.0 0.3925699805018692 14 Q9NR28,O95831,Q02978,Q9NR77,P31749 5 +Slender long bone 0.7372043510266784 2.5262299142854645 0.0115294000937666 1.0 0.3925699805018692 15 P37268,Q32P28,Q9Y619 3 +Subcutaneous nodule 0.6771137445958298 2.484362879188847 0.0129783479840484 1.0 0.4110693075763902 19 Q9NSE4,O75874,P31749,P48735,Q9NZ08,P49327,Q13510,P35637 8 +Abnormality of femur morphology 0.4946653338417298 2.454568273538053 0.0141053876710444 1.0 0.4274825988032658 70 O75844,O15360,P07602,Q96AY3,Q9Y487,Q14739,Q7RTS9,Q32P28,Q9Y619,Q7LGA3,Q9UHX1,O43909,P04062,O95613,O75718,P06280,O95831,Q99575,P28482 19 +Abnormal muscle fiber morphology 0.4828818699003668 2.424508593917698 0.0153291205052921 1.0 0.4479475908978951 73 P46976,P11047,P12235,P00846,Q70HW3,O43676,Q9BUK6,O75648,P61978,P07196,Q7LG56,P51114,Q99720,Q9Y5P6,Q9H2D1,Q8NI60,Q06210,P22626,P23786,O14979,P09651,O75340,O60313,O95831,P35637 25 +Abnormal circulating lipid concentration 0.4812510609561725 2.3875730139150497 0.0169600334962214 1.0 0.4736464727603928 80 P28070,Q15125,O75844,P37268,P42858,Q16836,Q8IWV7,Q9UBM7,Q15392,P23786,O43772,Q15800,P07602,P49257,Q14739,O95470,O75880 17 +Thin ribs 0.7472537713111009 2.383113717623598 0.0171668904060204 1.0 0.4736464727603928 13 O95831,Q32P28,Q9Y619 3 +Action tremor 0.5125154463400536 2.374785283712036 0.0175591612233489 1.0 0.4736464727603928 59 Q6PJG6,Q99720,Q5T8D3,Q9H6K4,Q9NR77,Q9NQ11,P07602,P31749,O75306,Q5JRX3,P41440,P00846,Q8N2K0,O95140,Q14108,P35637 16 +Rhizomelia 0.7703738108472478 2.3745553121013554 0.0175701035124353 1.0 0.4736464727603928 12 Q15125,Q03164,Q9UBM7,Q15392,O15228,O75718,Q14739,Q7RTS9 8 +Basal ganglia cysts 0.8870787925121286 2.3712479038433862 0.0177281358840108 1.0 0.4736464727603928 7 P00846 1 +Horizontal nystagmus 0.6135084274707532 2.368313752064122 0.0178693748719394 1.0 0.4736464727603928 26 Q9H061,Q9NSE4,O95831,P07602,P00846,O60313,P04062 7 +Abnormal conjunctiva morphology 0.6208212609330203 2.329954229467553 0.0198085703559494 1.0 0.4909955324600633 24 P10619,P28070,Q9NSE4,P31749,P34897,P06280,Q9NZ08,P49327,Q14739,Q13510 10 +Hypocholesterolemia 0.8263755383493521 2.3256668602955743 0.0200363297180867 1.0 0.4909955324600633 8 P07602,Q15800,P37268 3 +Abnormal circulating cholesterol concentration 0.5667872554323127 2.3026857326159775 0.0212965315140329 1.0 0.5044684755275043 36 Q15125,P37268,P42858,Q8IWV7,Q9UBM7,Q15392,Q15800,P07602,Q14739 9 +Polyneuropathy 0.6583766102820874 2.3019947206886813 0.0213354699003105 1.0 0.5044684755275043 18 Q15041,O95831,P07602,P00846,Q8N2K0,Q15120,O60313 7 +Abnormal femoral neck head morphology 0.520973886176745 2.298822221886457 0.0215150364162939 1.0 0.5059293411831542 48 O75844,Q9Y619,O95613,O95831,Q7LGA3,Q99575,O75718,Q96AY3,Q9Y487,O43909,P28482,Q14739,Q7RTS9 13 +Muscle stiffness 0.6573462149818262 2.296103531372584 0.0216699624412815 1.0 0.5070117845558123 18 P00846,P07602,Q15392,P23786 4 +Abnormal biliary tract morphology 0.6245687240514622 2.2767585143763136 0.0228006501323962 1.0 0.525543698101174 22 P14174,P07602,P09601,Q14739,Q14108,P04062 6 +Recurrent fractures 0.5887449648893356 2.268793577538594 0.0232808817253957 1.0 0.531351888791386 29 Q32P28,O75874,Q96AY3,P48735 4 +Barrel shaped chest 0.9401832715972857 2.2609283303185426 0.023763695475778 1.0 0.534965791202526 5 Q14739,Q7RTS9 2 +Abnormal circulating dicarboxylic acid concentration 0.544583052153161 2.2567281111676034 0.0240250691745005 1.0 0.534965791202526 40 Q14739,P41440,P48735,P37268 4 +Hypoplasia of the uterus 0.7837311063651782 2.2529876962357993 0.0242599247549548 1.0 0.534965791202526 9 Q16740 1 +Skin nodule 0.6085265866882328 2.252274387579386 0.0243049376791641 1.0 0.534965791202526 24 Q9NSE4,O75874,P31749,P48735,Q9NZ08,P49327,P06280,Q13510,P35637 9 +Wormian bones 0.6729404849822362 2.2481682639070675 0.0245654625191324 1.0 0.534965791202526 16 O95831,Q96AY3,Q32P28,O75844 4 +Increased susceptibility to fractures 0.5080119702707414 2.24424818909596 0.0248164370733279 1.0 0.534965791202526 53 Q32P28,P22626,O75874,Q13126,Q96AY3,P48735,Q14739,Q14108,P04062 9 +Abnormal cranial nerve physiology 0.4641969514213462 2.2355794115992498 0.0253793344686921 1.0 0.5420467031478463 73 P11047,P12235,Q9NR77,P07602,P34897,O15360,P48735,P07196,Q92734,Q9UHX1,Q13510,Q7LG56,P51530,Q9Y5P6,Q06210,O75874,P31749,Q96TA2,Q9NZ08,P49327,P42356 21 +Micromelia 0.6114046637861411 2.2319306481654033 0.0256195469085038 1.0 0.54467858632874 23 Q9UBM7,Q15392,O75874,P48735,Q9UHX1,Q14739 6 +Bilateral cryptorchidism 0.7697511754190145 2.2248044133545877 0.0260943710035717 1.0 0.5522517790574084 10 P37268 1 +Open mouth 0.5674243753614245 2.2200247749995157 0.026417085895978 1.0 0.556551818695356 33 Q96PZ0,Q86XL3,P30153,O43909,P04062 5 +Abnormal peripheral nervous system physiology 0.4940164231756107 2.2081135293577367 0.0272363601186973 1.0 0.5686658866038333 59 Q5TAQ9,Q99720,Q15125,Q9Y619,O95831,Q9NR77,P07602,O60313,P07196,O15270,Q15120,O95721,O95140,Q7LG56,Q8N2K0 15 +Abnormality of neutrophil morphology 0.9249572397626176 2.2024579057499913 0.0276329794296099 1.0 0.5734289537721097 5 Q14739 1 +Knee flexion contracture 0.5850162463729109 2.2013563522935966 0.0277108064000697 1.0 0.5734289537721097 27 Q9Y5P6,P37268,Q06210,Q86XL3,Q7LGA3,P23786,Q96AY3 7 +Contractures of the joints of the upper limbs 0.4614640346551659 2.1929750374069505 0.0283091776579 1.0 0.5779129210208858 79 Q8IZA0,Q99720,O75844,Q9Y619,P37268,Q15392,P23786,Q9NR77,P42892,P07196,Q96AY3,Q9UJX6,O43909,P35637 14 +Abnormal nerve conduction velocity 0.5087874170692216 2.1797490209705734 0.0292760706686452 1.0 0.5779129210208858 46 Q5TAQ9,Q99720,Q9Y619,O95831,Q9NR77,P07602,Q15120,O95140,Q7LG56,Q8N2K0 10 +Bulbar signs 0.7285816481221672 2.173780308428477 0.0297216380669125 1.0 0.5779129210208858 12 P00846,P07602,P04062,P35637 4 +Central scotoma 0.7585673456750086 2.1733797458373325 0.0297517479554874 1.0 0.5779129210208858 10 Q9H6K4,O75306,P00846,O95140,O60313 5 +Abnormal light and dark adapted electroretinogram 0.7911862106599807 2.172727145266322 0.0298008594609224 1.0 0.5779129210208858 8 P50897,P00846,Q15067 3 +Abnormal full field electroretinogram 0.7911862106599807 2.172727145266322 0.0298008594609224 1.0 0.5779129210208858 8 P50897,P00846,Q15067 3 +Increased cerebral lipofuscin 0.8842732203599101 2.1637183845587797 0.0304859691659609 1.0 0.5865399687467521 6 P50897,O75503 2 +Ragged red muscle fibers 0.6202023488391396 2.1514467069075423 0.0314409579707899 1.0 0.5950776435447072 19 Q9Y5P6,O75648,Q9H2D1,O95831,P12235,Q06210,P00846,Q70HW3,Q7LG56 9 +Impaired proprioception 0.5040686806996132 2.1402484994169493 0.0323346895762377 1.0 0.600159889403752 46 Q5TAQ9,Q9Y619,Q8IV08,Q9H6K4,Q9NR77,Q9NQ11,P41440,P00846,Q15120,O95140 10 +Abnormality of visual evoked potentials 0.606283409393322 2.129793176268719 0.033188692301759 1.0 0.600159889403752 21 P07602,O60313,O75503,Q15067 4 +Areflexia of lower limbs 0.5751685911770259 2.116742743517115 0.0342816870700126 1.0 0.600159889403752 26 Q15041,P12235,Q9H6K4,Q9NR77,Q15067,Q15120,O95140,Q7LG56,O60313 9 +Abnormal epiphyseal ossification 0.6355073264843982 2.1030025275224307 0.0354655485496013 1.0 0.600159889403752 17 P38435,Q14739,Q15125,Q7RTS9 4 +Mucosal telangiectasiae 0.7468382625723491 2.0851378315161475 0.0370567910816175 1.0 0.600159889403752 9 P10619,Q8IZA0,Q14739 3 +Hypoketotic hypoglycemia 0.8173024679913136 2.084054489682119 0.0371552110848207 1.0 0.600159889403752 7 P23786,O43772 2 +Postural instability 0.6204218520638046 2.0821469464434723 0.0373290495111413 1.0 0.600159889403752 18 P04062,P41440,O75503,Q9NR77 4 +Hypokinesia 0.6634055177977668 2.078197737173316 0.0376911504381041 1.0 0.600159889403752 14 O95831,P12235,Q9NQ11,Q7LG56,P04062 5 +Abnormal femoral neck morphology 0.5252238411029524 2.0777648445690517 0.037731023271343 1.0 0.600159889403752 39 O75844,Q9Y619,O95613,O95831,O75718,Q96AY3,Q9Y487,O43909,P28482,Q7RTS9 10 +Diminished movement 0.602096092800129 2.072330693601884 0.0382346118711167 1.0 0.600159889403752 20 P42858,O95831,P12235,Q9NQ11,Q7LG56,P04062 6 +Exostoses 0.889682593486851 2.065565567013701 0.0388695185164664 1.0 0.600159889403752 5 O75874,P48735 2 +Prenatal maternal abnormality 0.6836607591715657 2.0629229446368336 0.0391199497710594 1.0 0.600159889403752 13 Q14739 1 +Abnormality of peripheral nerves 0.4897419514595139 2.0622039247775628 0.0391883252136959 1.0 0.600159889403752 51 Q5TAQ9,Q99720,Q9Y619,O95831,Q9NR77,P07602,P07196,O15270,Q15120,O95140,Q7LG56,Q8N2K0 12 +Avascular necrosis 0.5946216585382129 2.0576714424112046 0.0396216835037506 1.0 0.600159889403752 21 O75844,Q9Y619,Q9NZ08,Q14108,P04062 5 +Limb undergrowth 0.4776034059805384 2.0421001151257365 0.0411416014818122 1.0 0.600159889403752 58 Q15125,Q6DKJ4,O95613,P98175,Q03164,Q15392,O75874,Q9UBM7,O15360,O15228,O75718,P48735,Q9UHX1,O43909,Q14739,Q7RTS9,O15111 17 +Progressive visual loss 0.5811441205977506 2.0401200954371723 0.0413383656706889 1.0 0.600159889403752 23 P50897,O75306,P31749,O75503,P00846,O60313 6 +Ectrodactyly 0.6124383383544513 2.0351548851293217 0.0418352908886374 1.0 0.600159889403752 18 Q99720,Q6DKJ4,P48449,Q9UBM7,Q9NR77,P07196 6 +Spondyloepimetaphyseal dysplasia 0.759923630564272 2.03444247059967 0.0419070034431878 1.0 0.600159889403752 8 O95831,Q7RTS9 2 +Dysdiadochokinesis 0.6233922318242252 2.033494039417882 0.0420026351633324 1.0 0.600159889403752 17 Q6DKK2,Q9BUK6,O75503,P41440 4 +Abnormality of the calcaneus 0.7595489154696835 2.032771244724108 0.0420756395669548 1.0 0.600159889403752 8 Q14739 1 +Distal muscle weakness 0.4418648538989962 2.0324860808147625 0.0421044714882909 1.0 0.600159889403752 74 Q5TAQ9,Q99720,Q9Y5P6,P11047,O95831,P22626,Q9NR77,P07196,P41440,P00846,O15270,O95140,Q7LG56,O43909,P35637 15 +Abnormal visual electrophysiology 0.4851494754408087 2.0324801670417756 0.0421050695860019 1.0 0.600159889403752 52 P50897,Q15555,P12235,Q15067,P07602,O43924,O75503,P00846,Q96S66,O95140,O60313 11 +Abnormality of the alveolar ridges 0.7349899865029743 2.0305016664816384 0.0423055719483305 1.0 0.600159889403752 9 P98175,Q9UBM7,Q15392 3 +Nasogastric tube feeding in infancy 0.7277246662055704 2.0298716738253013 0.0423695850581846 1.0 0.600159889403752 10 P06753,Q969N2,P61978,O75648,P07602,Q92734,Q9UHX1 7 +Muscle spasm 0.4652338059939936 2.0294691228663537 0.0424105308647133 1.0 0.600159889403752 64 P12235,Q9NR77,P00846,P53985,P07196,Q92734,P51530,Q7LG56,P04062,Q9Y5P6,Q06210,P23786,Q9H6K4,P09651,P06280,O75340,Q15165,Q92804,O95140,P35637 20 +Goiter 0.7346746852412342 2.029042868031442 0.0424539242099966 1.0 0.600159889403752 9 P31749,O75874,P48735,Q7LG56 4 +Eeg with focal spikes 0.879661807016521 2.0263175748800255 0.0427322513960297 1.0 0.600159889403752 5 O75503 1 +Neoplasm of the adrenal gland 0.653103935191813 2.022907487423194 0.0430826864575251 1.0 0.600159889403752 14 O75874,P48735 2 +Abnormal auditory evoked potentials 0.7262309908986841 2.022858809636688 0.0430877063239669 1.0 0.600159889403752 10 P07602,Q15125,O60313 3 +Coxa vara 0.6426049845307867 2.021140377826615 0.0432652355527278 1.0 0.600159889403752 15 O95613,O95831,O75718,Q96AY3,Q9Y487,Q7RTS9 6 +Increased bone mineral density 0.5666248919516841 2.0196328203059557 0.0434214881668038 1.0 0.600159889403752 25 Q15125,Q15392,Q13126,Q14739,Q14108 5 +Abnormal enchondral ossification 0.5489175471219453 2.0166706065018603 0.0437298993109087 1.0 0.6004518023506897 30 Q15125,Q9Y619,P38435,O43909,Q14739,Q7RTS9 6 +Psychomotor deterioration 0.7241781125448129 2.013210999685685 0.0440924365429298 1.0 0.6004518023506897 10 P50897,P07602,Q9Y487 3 +Aplasia hypoplasia of the patella 0.8450885301747539 2.0085156639051234 0.044588523228827 1.0 0.6004518023506897 6 Q96AY3 1 +Aplasia hypoplasia involving the vertebral column 0.6298024534065899 2.0082079033055775 0.0446212035252016 1.0 0.6004518023506897 16 O95831,Q14739,Q7RTS9 3 +Slowly progressive 0.473231476439343 2.0018205260090234 0.0453040375392426 1.0 0.6035594619147735 58 Q99720,O95831,P12235,Q8IV08,Q9NR77,O14979,O95140,P41440,Q15120,P51530,Q8N2K0 11 +Neonatal hypoglycemia 0.7216358006348601 2.0012478458241674 0.0453656871280021 1.0 0.6035594619147735 10 Q16836,O43772 2 +Positive romberg sign 0.7263177689513471 1.9902867381255895 0.0465593580684431 1.0 0.6072279304388549 9 O95140,Q8IV08,Q9H6K4,P41440 4 +Biliary tract abnormality 0.5553650787167689 1.9837918317733203 0.0472790511029128 1.0 0.6129338282145597 26 P14174,Q5XKP0,P07602,P09601,Q14739,Q14108,P04062 7 +Abnormality of skull ossification 0.6897657839329815 1.982781951927604 0.0473917908413319 1.0 0.6129338282145597 12 Q14739,Q32P28,O75844 3 +Cogwheel rigidity 0.7927495810277515 1.980665806369748 0.047628763793017 1.0 0.614292310859522 7 P00846,Q7LG56 2 +Aplasia hypoplasia of the sternum 0.8671765496019138 1.9771986722504375 0.0480191776442817 1.0 0.617616826275624 5 P98175,Q9Y619 2 +Hand muscle weakness 0.6663912423080296 1.973783781712404 0.048406333748574 1.0 0.6178177677058059 13 Q15120,O95140,P11047,Q9NR77 4 +Abnormal lung lobation 0.622644601110416 1.9677210947152912 0.0491001373027528 1.0 0.6178177677058059 16 Q9UBM7,O43683,P21964,P31749,O60566,Q9UHX1,Q14739,Q15645 8 +Respiratory arrest 0.7213926461360167 1.9673636465935624 0.0491413022627935 1.0 0.6178177677058059 9 O43772 1 +Scotoma 0.664844908992859 1.9657565893620876 0.0493267345127639 1.0 0.6178177677058059 13 Q9H6K4,O75306,P00846,O95140,O60313 5 +Hypomimic face 0.7063581126701365 1.9625138853897464 0.049702685621209 1.0 0.6178177677058059 11 P12235,Q7LG56,P35270,P04062 4 +Talipes equinovarus 0.4407678848727578 1.9582374455316407 0.0502021571377286 1.0 0.6216522437054913 81 Q15125,P11047,Q9Y619,Q8NI60,P61978,P98175,Q15392,Q9NR77,Q8NCH0,P21964,P42356,Q96AY3,Q9Y487,Q9NWM8,Q9UJX6,P28482,Q7RTS9 17 +Rigidity 0.4699209191474742 1.9569206976429088 0.0503567927090982 1.0 0.6219130685770855 57 Q6PJG6,P42858,P12235,Q15392,Q96CU9,Q9H6K4,Q9NQ11,P07602,P35270,P00846,Q7LG56,P04062 12 +Abnormal delivery 0.5723414357673365 1.949798956141117 0.05120008604012 1.0 0.6306550280497327 22 O75844,Q9Y619,Q9UBM7,Q9Y487,O60313 5 +Abnormal pupillary function 0.7400786003490942 1.94548903022093 0.0517161487259596 1.0 0.6326528041381896 8 P07602,Q9NR77 2 +Abnormal circulating acetylcarnitine concentration 0.8289936874797625 1.943997662283845 0.051895733005228 1.0 0.6326528041381896 6 P23786,O43772 2 +Abnormality of hair pigmentation 0.5605471016091511 1.9420339907430344 0.0521329855295198 1.0 0.6326528041381896 24 Q86YV9,P37268,Q8IWV7,Q9UBM7,Q6PGP7,Q13126 6 +Abnormal ossification involving the femoral head and neck 0.8581823263896597 1.9416659704241337 0.0521775508567579 1.0 0.6326528041381896 5 Q14739 1 +Multiple enchondromatosis 0.8280353507137148 1.9401421598336672 0.0523624155304975 1.0 0.6328682278723354 6 P48735 1 +Emg impaired neuromuscular transmission 0.8278212745942022 1.9392806941684588 0.052467168376014 1.0 0.6328682278723354 6 Q9Y5P6,O60313,Q06210,P11047 4 +Demyelinating peripheral neuropathy 0.5841560106849 1.9334394581077683 0.0531820844034356 1.0 0.6381850128412276 19 P00846,Q7LG56,P41440,Q9NR77 4 +Biliary cirrhosis 0.8242284825743399 1.924811375055916 0.0542529604053245 1.0 0.6390414486446943 6 Q14739,P09601 2 +Sensory axonal neuropathy 0.6046137988273924 1.9246245647851832 0.0542763439493036 1.0 0.6390414486446943 17 O95831,P22626,Q8IV08,Q15067,Q9NQ11,P34897,P09651,O95140 8 +Megaloblastic anemia 0.7351064841839138 1.9230606983310683 0.0544724273764116 1.0 0.6390414486446943 8 P00374 1 +Xerostomia 0.5929641209018204 1.9194336257661673 0.054929478814085 1.0 0.6425920938652764 18 Q14739,Q92804,P35637 3 +Abnormality of the tarsal bones 0.5427676057142513 1.915130280643691 0.0554758909959793 1.0 0.6455983366348979 27 Q15125,O75844,P98175,Q14739,Q7RTS9 5 +Contractures of the joints of the lower limbs 0.4666945879635192 1.913840644970472 0.0556405203441032 1.0 0.6455983366348979 56 Q8IZA0,Q99720,Q9Y5P6,P37268,Q08J23,Q06210,Q86XL3,Q7LGA3,P23786,Q96AY3,Q9UJX6,O60313,Q8N2K0,P35637 14 +Thoracic kyphosis 0.5918980961965191 1.9130543615437032 0.0557410934981161 1.0 0.6455983366348979 18 O95831,P51648,Q9UHX1,O43909,Q7RTS9,P04062 6 +Abnormality of tibia morphology 0.6544563991624842 1.9116353012179117 0.0559229881497647 1.0 0.6460978482017481 13 Q7RTS9,Q32P28 2 +Abnormality of the glenoid fossa 0.988578298767658 1.9051263407199148 0.0567636501498987 1.0 0.6541870175691297 2 Q7RTS9 1 +Inability to walk 0.4427655780666943 1.902893131238136 0.0570544914374517 1.0 0.6549423598176586 90 O14949,Q99720,Q9BUK6,Q15041,P42858,P12235,Q96CU9,Q9NR77,P30153,O95140,O75503,P07196,P00846,O15270,Q7RTS9,Q7LG56,O43909,P35637 18 +Hypoplasia of the odontoid process 0.7286766561877445 1.8939736420408175 0.0582285085502074 1.0 0.6580386791499171 8 O95831,Q7RTS9 2 +Slow decrease in visual acuity 0.7047096758619076 1.889264963637977 0.0588563337537928 1.0 0.6635232202364636 9 O75306,P31749,P00846 3 +Abnormality of fontanelles 0.4710037020040335 1.887933679990094 0.0590348543612098 1.0 0.6639282171637508 50 Q15125,Q32P28,O75844,Q9Y619,Q08J23,Q8IWV7,P98175,P20674,Q8NCH0,O75718,Q9Y487,Q16134,O15228,O15111 14 +Red eye 0.5979782901185378 1.885827185625412 0.0593182462322314 1.0 0.6655078420657102 17 P28070,Q9NSE4,P34897,Q9NZ08,Q14739 5 +Keratoconjunctivitis 0.7027140208469531 1.879876281250379 0.0601249411569864 1.0 0.6701848549948739 9 Q9NSE4,Q14739,Q9NZ08 3 +Atlantoaxial abnormality 0.8421769275312337 1.8781343954180825 0.0603627820785777 1.0 0.6701848549948739 5 Q8NCH0,Q7RTS9 2 +Amyotrophic lateral sclerosis 0.5747879610378828 1.875869293864623 0.0606732299797625 1.0 0.6701848549948739 19 P22626,Q99720,Q92804,P35637 4 +Postaxial polydactyly 0.5607799461874297 1.8757033929408375 0.0606960197602832 1.0 0.6701848549948739 22 Q15125,P98175,Q9UBM7,O43924,P30153,O43909,Q14739 7 +Akinesia 0.7017665771684175 1.8754155280030085 0.0607355805478784 1.0 0.6701848549948739 9 Q9NQ11,P51114,P04062 3 +Retrognathia 0.4321774274697278 1.8753637433878712 0.0607426994862192 1.0 0.6701848549948739 80 Q15125,P53701,O75844,Q9Y619,P37268,Q96PZ0,Q15392,Q8NCH0 8 +Aplasia hypoplasia of the uterus 0.5955458109998569 1.871562040151037 0.0612672192041534 1.0 0.6743739305308238 17 Q16740,P53701 2 +Skin ulcer 0.5191355063302967 1.8703538725462736 0.0614346930302185 1.0 0.6746224781808904 33 Q8IZA0,O75874,Q03518,P48735,Q14739,O15270,P04062 7 +Limited elbow movement 0.4946875322259108 1.865142378832637 0.0621614497079414 1.0 0.6771343451898033 40 P37268,P23786,Q96AY3,O43909,Q7RTS9 5 +Limb ataxia 0.535151856510954 1.8625184520175988 0.0625300470032164 1.0 0.6786477828600829 27 Q9BUK6,Q8IV08,Q9NR77,P41440,Q14108,P04062 6 +Narrow mouth 0.4263854485627821 1.858650482948222 0.0630766964662865 1.0 0.6814039414084226 75 O75648,O75844,Q9Y619,Q9NSE4,Q96PZ0,P42858,Q15555,Q15392,Q7LGA3,Q8NCH0,P31749,Q6PGP7,Q9Y487,O43909,P28482,P04062 16 +Muscle fiber inclusion bodies 0.6897550166096883 1.8498125460136623 0.0643405719722809 1.0 0.6883554453957308 10 Q9Y5P6,O43676,Q06210,P07196,P09651,O75340 6 +Neuronal loss in central nervous system 0.620906404157358 1.847769859563687 0.0646356428880057 1.0 0.6883554453957308 14 Q6PJG6,P42858,P07602,P35637,P04062 5 +Impaired tactile sensation 0.6822869142782748 1.8462152629460384 0.064860955654578 1.0 0.6883554453957308 11 Q5TAQ9,O15270,Q9NR77 3 +Steppage gait 0.5459725106092841 1.845543214006612 0.064958558317349 1.0 0.6883554453957308 24 Q5TAQ9,Q9NR77,Q15120,O95140,O15270 5 +Respiratory distress 0.4605806872730336 1.845285499263546 0.0649960187372544 1.0 0.6883554453957308 55 P62857,P53701,O75648,P11047,Q9Y619,O95831,P23786,O75306,P07602,Q16134,Q9UHX1,P00846,P04062 13 +Increased muscle lipid content 0.6881954728648788 1.8423379296682307 0.065425734915693 1.0 0.6883554453957308 10 Q9BUK6,O75648,Q8NI60,P23786 4 +Genu varum 0.6807978604480619 1.838970837026747 0.0659194755903584 1.0 0.6897102884240655 11 Q7RTS9 1 +Toxemia of pregnancy 0.8020432142748865 1.8349880692301443 0.0665074572427493 1.0 0.6917014093878165 6 Q14739 1 +Cerebral palsy 0.6865957152210185 1.834664184912036 0.0665554620716799 1.0 0.6917014093878165 10 P35270,O75874,P48735 3 +Astrocytoma 0.6785603057254344 1.82807398139196 0.0675384492315192 1.0 0.6964764288749707 11 O75874,P48735 2 +Heterogeneous 0.4671128302720163 1.8246557648946116 0.0680529925060073 1.0 0.6994585719822746 46 O75844,Q9Y619,Q16836,P12235,Q9NR77,P31749,P07196,P00846 8 +Limb joint contracture 0.4467637110972697 1.8060720369998209 0.0709070880219515 1.0 0.7177030474569706 108 O75844,P37268,Q15392,Q9NR77,Q96AY3,Q9UJX6,Q8IZA0,Q9Y619,P07196,O43909,Q99720,Q9Y5P6,Q6DKJ4,P23786,P42892,O60313,Q8N2K0,Q86XL3,P35637 19 +Abnormality of the wrist 0.5001001000485383 1.8028094929274676 0.0714181388081065 1.0 0.7213077099577963 36 Q15125,O75844,P11047,O95831,Q9H6K4,P31749,O43909,Q7RTS9 8 +Abnormality of salivation 0.4600406280397707 1.7989880558979965 0.0720205701063494 1.0 0.722689168998196 51 Q15165,Q92804,P55795,Q9NR77,O43909,Q14739,P42356,P35637 8 +Abnormality of the metaphysis 0.4508418451822426 1.7927690992728722 0.0730098524026174 1.0 0.7281437427789886 58 O95831,O75874,Q13126,P48735,O43909,Q14739,Q9HC07,Q7RTS9 8 +Abnormal diaphysis morphology 0.4308547581614667 1.7911768425446994 0.073264921105393 1.0 0.7281437427789886 69 Q32P28,Q9Y619,Q9NR77,Q13126,Q96AY3,Q9Y487,Q14739,Q9HC07,Q7RTS9 9 +Talipes calcaneovalgus 0.7910153408449007 1.790040008254624 0.0734474798920128 1.0 0.7281437427789886 6 Q9UBM7,Q9NR77 2 +Multiple prenatal fractures 0.7909586227056977 1.7898083318278304 0.0734847293007208 1.0 0.7281437427789886 6 Q14739,Q32P28 2 +Pericarditis 0.82005173712273 1.789697947039973 0.0735024826258858 1.0 0.7281437427789886 5 P14174,O15460,Q9NZ08 3 +Hypothermia 0.6760316847872463 1.7838289653539303 0.0744514613603217 1.0 0.73156820089886 10 P00846 1 +Peripheral demyelination 0.5703650709950376 1.7832141644062671 0.0745514476075275 1.0 0.73156820089886 18 P00846,P07602,Q9NR77 3 +Abnormality of the odontoid process 0.6819627676457146 1.7816718963694158 0.0748027524334034 1.0 0.7316840658191728 9 O95831,Q7RTS9 2 +Temperature instability 0.7880427488113859 1.7778910332619728 0.0754217531962304 1.0 0.7361922072990545 6 P35270 1 +Undetectable light and dark adapted electroretinogram 0.8151513914119422 1.7700180287059812 0.0767241374369382 1.0 0.7442241331383015 5 P00846 1 +Pulmonary infiltrates 0.6783357967719179 1.7644002747894107 0.0776646119509882 1.0 0.7473534969514539 9 P15260,Q9NZ08,P49327,Q13510,P04062 5 +Limb girdle muscle weakness 0.5205861143575785 1.7610354651840925 0.0782324005453503 1.0 0.7473534969514539 27 Q9Y5P6,P12235,Q06210,O14979,P07602,Q13126,O75340,P51530,Q7LG56,O60313 10 +Difficulty walking 0.4244638624768624 1.756730870788583 0.0789636930039034 1.0 0.7503162339309687 84 Q99720,Q9Y5P6,Q9BUK6,Q15041,P42858,Q15067,Q9NR77,P07602,P51530,P31749,O95140,Q9NQ11,P00846,Q15120,Q7RTS9,P35637 16 +Aplasia hypoplasia involving the skeletal musculature 0.6763431879692653 1.7548980990804288 0.0792767393908722 1.0 0.751756616301224 9 Q9Y487,Q9NR77 2 +Dementia 0.4399815450690782 1.7483017694523146 0.0804117870146208 1.0 0.7517979355278995 62 Q9NQZ5,P17900,P04080,P09651,P42858,P22626,P35637,Q9NQ11,P07602,O15118,O60313,Q9Y487,P00846,Q13510,Q06787,Q7LG56,Q14108,P04062 18 +Broad palm 0.6746123490710045 1.7466365623620252 0.080700400800975 1.0 0.7517979355278995 9 Q14739,Q7RTS9 2 +Elbow flexion contracture 0.5161393939088349 1.7464412097968405 0.0807343143822916 1.0 0.7517979355278995 28 P23786,Q96AY3,P37268 3 +Short middle phalanx of finger 0.7792445145763442 1.7418517964339713 0.0815343805345301 1.0 0.7553449294114597 6 O95613,Q03164,Q9UHX1 3 +Abnormal corneal epithelium morphology 0.5832528263604545 1.7415301398800995 0.0815906948804789 1.0 0.7553449294114597 16 O75844,Q9NSE4,Q9NZ08,P49327,Q14739 5 +Abnormal thoracic spine morphology 0.5097253932916206 1.7369088831789727 0.0824032552032336 1.0 0.7597416954975365 30 O75844,Q9NSE4,O95831,P51648,Q9UHX1,O43909,Q7RTS9,P04062 8 +Epispadias 0.8059930511812694 1.7331510120141087 0.0830688314934411 1.0 0.7615575144518797 5 Q9Y619 1 +Foot dorsiflexor weakness 0.4909232058653013 1.7317639051807974 0.0833156071934599 1.0 0.7615575144518797 36 Q99720,Q9NR77,Q7LG56,Q14739,O95140,O15270 6 +Neoplasm of the adrenal cortex 0.734741202313492 1.7317310846246887 0.0833214533765445 1.0 0.7615575144518797 7 P48735 1 +Atlantoaxial instability 0.9458972046889038 1.7311891902492222 0.0834180267118682 1.0 0.7615575144518797 2 Q7RTS9 1 +Neck flexor weakness 0.8049611152219902 1.7289899711443149 0.0838108900041003 1.0 0.7630912770942775 5 Q99720,Q7LG56,P35637 3 +No social interaction 0.944995491433725 1.7275010788841014 0.0840777115870623 1.0 0.7630912770942775 2 Q15067 1 +Abnormality of the ischium 0.9449954914337246 1.7275010788840988 0.0840777115870627 1.0 0.7630912770942775 2 Q8IZA0 1 +Proximal muscle weakness 0.4280932740906719 1.7204581867508184 0.0853491879759675 1.0 0.7667710112091493 67 P11047,P12235,P00846,Q8NFF5,Q9BUK6,P07196,Q92734,Q13510,P51530,Q7LG56,P51114,Q99720,Q9Y5P6,Q8NI60,Q06210,P22626,Q13126,P09651,O60313,Q5T8D3,O95140,P35637 22 +Intellectual disability progressive 0.6180501438320409 1.7193485284808312 0.0855509285026003 1.0 0.7667710112091493 13 O95831,P53701,Q15067 3 +Macrovesicular hepatic steatosis 0.7311328023344021 1.7160383100510426 0.0861550308625198 1.0 0.7667710112091493 7 Q5XKP0,P23786,Q7LG56 3 +Retrocollis 0.9419897805831056 1.7152040606283148 0.0863078206599232 1.0 0.7667710112091493 2 P35637 1 +Decreased absent ankle reflexes 0.5586379269920431 1.7117238901267229 0.086947563826224 1.0 0.7672344250886546 18 Q15041,P12235,Q9H6K4,Q15120,O95140,Q7LG56,O60313 7 +Hypopigmentation of the fundus 0.8947028943336388 1.7106886786271889 0.0871385987563964 1.0 0.7672344250886546 4 Q9Y619 1 +Fibrous tissue neoplasm 0.5482092108456762 1.710514633614663 0.0871707497577101 1.0 0.7672344250886546 19 P31749,Q15392,Q13126 3 +Aplasia hypoplasia involving the metacarpal bones 0.505603739338166 1.706985023870037 0.0878248360218985 1.0 0.7715328990904895 30 Q14739,Q7RTS9,Q32P28 3 +Abnormal form of the vertebral bodies 0.4252132842494255 1.7046677869553737 0.0882564009551236 1.0 0.7730900571342896 91 Q15125,Q32P28,Q9Y619,O95831,O75874,P31749,Q96AY3,P48735,O43909,Q14739,Q7RTS9 11 +Hypergonadotropic hypogonadism 0.5669949191156755 1.7024410254288949 0.0886727249585794 1.0 0.7730900571342896 17 P48449,Q16740 2 +Abnormal metatarsal morphology 0.5072598812649324 1.7005394147245556 0.0890295091144519 1.0 0.7730900571342896 29 O96028,O43505,Q15392,Q9UBM7,P31749,P28482,Q7RTS9 7 +Undetectable electroretinogram 0.7977538255457295 1.6998897796929713 0.0891516596958803 1.0 0.7730900571342896 5 P50897,Q96S66 2 +Femoral bowing 0.6645338774620531 1.698390338518868 0.0894341143781534 1.0 0.7730900571342896 9 Q7RTS9 1 +Breast carcinoma 0.5333615653871363 1.6975269089649436 0.0895970881492134 1.0 0.7730900571342896 22 O75874,P48735 2 +Abnormal platelet volume 0.6854361043639975 1.695981177755755 0.0898894446774298 1.0 0.7730900571342896 8 Q14739 1 +Venous thrombosis 0.5934860321417139 1.695884445031285 0.0899077660147649 1.0 0.7730900571342896 14 P31749,O75874,P48735,Q9NZ08 4 +Abnormal subcutaneous fat tissue distribution 0.7947117476124375 1.6875871831333298 0.0914905012702949 1.0 0.7787564422568429 5 Q9Y487 1 +Clumsiness 0.5207299996490821 1.6759793570934298 0.0937422361071296 1.0 0.7846578185789949 24 P07602,Q9NR77,O75503,Q15067 4 +Mandibular aplasia 0.7916583516889215 1.675227176688365 0.0938896673226403 1.0 0.7846578185789949 5 Q9Y619 1 +Distal lower limb muscle weakness 0.5336968870059875 1.6709145904949605 0.0947385491607026 1.0 0.7846578185789949 21 Q9NR77,P07196,P00846,O95140,O43909 5 +Limb muscle weakness 0.4189602281466835 1.6704950688408815 0.094821454253221 1.0 0.7846578185789949 87 Q99720,Q15120,P12235,Q9NR77,Q15067,P31749,Q13126,O95140,P07196,P00846,O15270,Q14739,Q7RTS9,Q7LG56,O43909 15 +Cerebral inclusion bodies 0.6275733854004336 1.6677735855422593 0.0953606813642571 1.0 0.7846578185789949 12 O15118,P04062,P22626,P09651 4 +Angioid streaks of the fundus 0.9302675082657051 1.6672008060942882 0.0954744825148898 1.0 0.7846578185789949 2 P31749 1 +Joint hemorrhage 0.9302675082657051 1.6672008060942882 0.0954744825148898 1.0 0.7846578185789949 2 P49257 1 +Hamartoma 0.5327585956969849 1.6648299601719625 0.0959466848333208 1.0 0.7846578185789949 21 P31749,Q02978,O75874,P48735 4 +Mitochondrial respiratory chain defects 0.7603780233817564 1.6641752118632112 0.0960774201962784 1.0 0.7846578185789949 6 O75306,P00846,Q4J6C6 3 +Hypoplasia of the musculature 0.7884898228801708 1.6623889695151135 0.0964348091414697 1.0 0.7846578185789949 5 Q9NR77 1 +Sensory neuropathy 0.4727517950130682 1.6619123283475197 0.0965303544158824 1.0 0.7846578185789949 39 Q15041,Q9NSE4,O95831,P22626,Q8IV08,Q15067,Q9NQ11,P00846,O95140,O15270,O60313 11 +Visual hallucinations 0.7594244648517926 1.6602353541766166 0.0968671149377582 1.0 0.7846578185789949 6 Q9NQ11,P04062 2 +Abnormal speech prosody 0.7169363224162267 1.6540755925236852 0.0981121545675887 1.0 0.7846578185789949 7 P00846 1 +Abnormal pupillary light reflex 0.7858284932649766 1.651596405568785 0.0986168532666289 1.0 0.7846578185789949 5 P07602,Q9NR77 2 +Slow pupillary light response 0.7858284932649766 1.651596405568785 0.0986168532666289 1.0 0.7846578185789949 5 P07602,Q9NR77 2 +Skeletal dysplasia 0.4583097109009176 1.6508867556815854 0.0987617007045984 1.0 0.7846578185789949 43 O95831,P31749,O43909,P10619,Q14739,Q9HC07,Q7RTS9 7 +Chondrosarcoma 0.9699338544798536 1.6475106153561196 0.0994531361086226 1.0 0.7846578185789949 3 O75874,P48735 2 +Obsessive compulsive trait 0.7846443650499784 1.6467916461310088 0.0996008790402347 1.0 0.7846578185789949 5 O75503 1 +Metatarsus adductus 0.5669858219610056 1.6464939495440407 0.099662104750589 1.0 0.7846578185789949 16 O96028,Q9UBM7,Q15392,P28482 4 +Abnormal vitamin b12 level 0.7556468624551353 1.644614518227629 0.1000493309625054 1.0 0.7846578185789949 6 P41440 1 +Abnormal circulating citrulline concentration 0.7840125493513129 1.6442272862503085 0.1001292626644372 1.0 0.7846578185789949 5 P00846 1 +Patchy changes of bone mineral density 0.8769234606119543 1.6426959584508576 0.1004458554127472 1.0 0.7846578185789949 4 Q14739 1 +Postaxial foot polydactyly 0.6525333302949127 1.6406364396377504 0.1008729060698174 1.0 0.7846578185789949 9 O43909,Q14739,Q9UBM7 3 +Abnormality of the 5th toe 0.6525333302949127 1.6406364396377504 0.1008729060698174 1.0 0.7846578185789949 9 O43909,Q14739,Q9UBM7 3 +Abnormality of the anterior fontanelle 0.4848703490421529 1.635908261118601 0.1018587887729045 1.0 0.7846578185789949 34 Q15125,Q32P28,P20674,Q9Y619,Q08J23,Q8IWV7,O75718,Q9Y487,Q16134,O15111 10 +Abnormal middle phalanx morphology of the hand 0.6453795310663661 1.634777951774232 0.1020956043846714 1.0 0.7846578185789949 10 O95613,P35453,Q03164,Q9UHX1,O60828 5 +Meningitis 0.7531893656163529 1.6344416456343829 0.102166149746554 1.0 0.7846578185789949 6 P49327,O15460,Q9NZ08,P02786 4 +Neoplasm of the parathyroid gland 0.781422981167122 1.6337120429431349 0.1023193284513941 1.0 0.7846578185789949 5 P48735 1 +Abnormality of the parathyroid morphology 0.781422981167122 1.6337120429431349 0.1023193284513941 1.0 0.7846578185789949 5 P48735 1 +Parathyroid adenoma 0.781422981167122 1.6337120429431349 0.1023193284513941 1.0 0.7846578185789949 5 P48735 1 +Segmental peripheral demyelination remyelination 0.7528080649565876 1.632862483627023 0.1024979220487467 1.0 0.7846578185789949 6 P00846,Q9NR77 2 +Tibial bowing 0.7807674686692303 1.6310490115802816 0.1028799782184191 1.0 0.7846578185789949 5 Q7RTS9 1 +Abnormal facial expression 0.4809650854775357 1.6292727028898677 0.1032553021143443 1.0 0.7846578185789949 35 Q9Y5P6,Q9BUK6,P12235,Q9NR77,Q9NQ11,P35270,P51530,Q7LG56,P04062 9 +Abnormality of fundus pigmentation 0.7509851871071063 1.625310215356119 0.1040964758755289 1.0 0.7888954002316011 6 Q9Y619 1 +Insidious onset 0.7499353771291882 1.6209587164414176 0.1050264928449049 1.0 0.7912675577441383 6 P04062,Q9NR77 2 +Epiphyseal dysplasia 0.7087335178455453 1.6181157150656371 0.1056376623804142 1.0 0.7941935853481302 7 O43909,Q7RTS9 2 +Aplasia hypoplasia of the skin 0.4296565852014291 1.617151658646213 0.105845548235784 1.0 0.7941935853481302 60 P53701,Q15125,O75844,Q9Y619,Q8IWV7,Q15392,Q8NCH0,Q13126 8 +Abnormal glial cell morphology 0.4250181974281353 1.6167762264661707 0.1059265928911488 1.0 0.7941935853481302 63 Q6PJG6,Q7KZN9,P42858,O95831,O75874,O75306,Q9UJX6,Q16134,P48735,P00846,Q92734,P35637,P04062 13 +Impaired temperature sensation 0.7074518835219705 1.6124871005229653 0.1068559847184844 1.0 0.7979580312665678 7 O15270,Q9NR77 2 +Bilateral talipes equinovarus 0.7470782335516699 1.60910809973211 0.1075927064652921 1.0 0.7979580312665678 6 Q15125,Q15392 2 +Epiphyseal stippling 0.6161343323688885 1.608679891227567 0.1076863550159161 1.0 0.7979580312665678 12 P38435,Q14739,Q15125 3 +Dysesthesia 0.7469004188063797 1.6083702070828472 0.1077541226784153 1.0 0.7979580312665678 6 Q8NCH0,O15270,Q9NR77 3 +Arterial thrombosis 0.7062894344470724 1.6073795862385432 0.1079711253646773 1.0 0.7979580312665678 7 P31749,O15460,Q9NZ08 3 +Abnormality of the carpal bones 0.5310429999351178 1.602173857523134 0.1091171693025885 1.0 0.7983376177862395 19 O43909,Q15125,Q7RTS9 3 +Impaired pain sensation 0.5271417042328489 1.6019370244355609 0.1091695361367037 1.0 0.7983376177862395 20 P61978,O95831,Q9NR77,P07196,O95140,O15270 6 +Visual loss 0.4386951671847551 1.5977238933165865 0.1101044388146621 1.0 0.798514434768017 50 P50897,P53701,P48449,O75306,P07602,P31749,O75503,P00846,O95140,O60313 10 +Orthostatic hypotension due to autonomic dysfunction 0.6636651124866406 1.5947961191949291 0.1107578351720759 1.0 0.8020038577934456 8 Q6Y7W6,P07602,O43681,P04062 4 +Variable expressivity 0.4034022687972806 1.5900027272594817 0.1118341902930397 1.0 0.8031533599964955 77 Q9Y5P6,Q15125,Q9H061,P17900,Q8NI60,Q70HW3,P00374,Q06210,Q9NR77,P07602,P07196,Q6P4A7,P35270,O95470,O95140 15 +Impaired vibratory sensation 0.4694575196354511 1.588888673309026 0.1120855288236681 1.0 0.8031533599964955 37 Q5TAQ9,Q9Y619,Q9NR77,Q9NQ11,P00846,Q15120,O95140 7 +Metaphyseal dysplasia 0.593730497831674 1.588707174809922 0.1121265183513617 1.0 0.8031533599964955 13 O95831,Q7RTS9,O43909 3 +Abnormality of cranial sutures 0.4106986169960387 1.5884453732879185 0.1121856642961245 1.0 0.8031533599964955 86 Q32P28,O75844,Q9Y619,O95831,P61978,P98175,Q08J23,Q02224,P21964,Q8NCH0,P31749,O75718,P30153,Q96AY3,Q9Y487,Q9UJX6,O43909,P28482 18 +Hepatic failure 0.4368425032880123 1.5881912545039705 0.1122430980932052 1.0 0.8031533599964955 51 Q9Y619,Q16836,Q8IWV7,O43772,P23786,Q6PGP7,P00846,P04062 8 +Abnormal sensory nerve conduction velocity 0.701810736268107 1.587680767827429 0.112358544084703 1.0 0.8031533599964955 7 Q7LG56,Q9NR77 2 +Mesomelia 0.7016779487990493 1.5870962307897436 0.1124908514433475 1.0 0.8031533599964955 7 Q14739,Q9UBM7 2 +Alveolar ridge overgrowth 0.9107303877366898 1.5870686370980351 0.1124971001874919 1.0 0.8031533599964955 2 Q15392 1 +Hyperintensity of cerebral white matter on mri 0.5280996266221446 1.5834799398118649 0.113312115349843 1.0 0.8047405239672715 19 P07602,P17900,Q9BUK6,O75503 4 +Abnormal circulating bilirubin concentration 0.4974387406373644 1.5831701612231663 0.1133826855074162 1.0 0.8047405239672715 26 Q14739,P41440 2 +Abnormality of the knee 0.4137602753516349 1.57881203797015 0.1143791766017603 1.0 0.8056395803390533 91 Q9Y5P6,Q15125,Q15041,P11047,Q9Y619,P37268,O95831,Q9NSE4,Q86XL3,P23786,Q9NR77,Q96AY3,Q7RTS9 13 +Enchondroma 0.6330942415974468 1.5744177997863302 0.1153908914094603 1.0 0.8056395803390533 10 P48735 1 +Abnormal pupil morphology 0.6093449964410912 1.5734469226758998 0.1156153692658288 1.0 0.8056395803390533 12 P11047,Q9NR77 2 +Abnormal acetabulum morphology 0.5226443097233786 1.5729564474369224 0.1157289031904669 1.0 0.8056395803390533 20 O43909,Q7RTS9,Q96AY3 3 +Abnormal iliac wing morphology 0.6264585525674657 1.5707582804922648 0.1162388060531229 1.0 0.8056395803390533 11 Q7RTS9 1 +Response to drugs acting on neuromuscular transmission 0.8580451127819557 1.5702281004405814 0.1163620543387236 1.0 0.8056395803390533 4 Q06210,Q9Y5P6,P11047 3 +Emg decremental response of compound muscle action potential to repetitive nerve stimulation 0.8580451127819557 1.5702281004405814 0.1163620543387236 1.0 0.8056395803390533 4 Q06210,Q9Y5P6,P11047 3 +Short ribs 0.6322029511550502 1.5700254832155007 0.1164091828516098 1.0 0.8056395803390533 10 Q14739 1 +Sarcoma 0.4203275318345165 1.5698461410239235 0.1164509101306234 1.0 0.8056395803390533 63 P62857,Q92804,Q01844,Q15392,O75874,P31749,Q13126,O60566,P48735 9 +Temporal pattern 0.6573123696360511 1.5650936979103904 0.1175609410494682 1.0 0.8094159148498348 8 P04062,Q9NR77 2 +Hyporeflexia of upper limbs 0.9470715994884956 1.5626879883010016 0.1181260010416218 1.0 0.8110769002191148 3 Q9NR77 1 +Vertebral compression fracture 0.561066050412849 1.5605276454871952 0.1186352421722409 1.0 0.8110769002191148 15 Q96AY3,Q32P28,Q14108,P04062 4 +Low frustration tolerance 0.6562108899587195 1.5599358809690864 0.1187750342099178 1.0 0.8110769002191148 8 Q6Y7W6,P04062,Q9UHX1 3 +Limb pain 0.6299952142276625 1.559138107479783 0.11896369593109 1.0 0.8110769002191148 10 P00846,O15270 2 +Weak cry 0.6356981790594017 1.559074072637736 0.1189788494092902 1.0 0.8110769002191148 9 Q06210,Q13510,O60313,P11047 4 +Morphological abnormality of the pyramidal tract 0.5071660390515587 1.5528715317257764 0.120453829183512 1.0 0.8163508423266839 23 P00846,O95831,Q9Y619 3 +Decreased size of nerve terminals 0.901112113014729 1.5475800070858703 0.1217234480272893 1.0 0.8182357861027015 2 P11047 1 +Decreased ldl cholesterol concentration 0.8517767069407383 1.5461114585860256 0.1220776519105633 1.0 0.8182357861027015 4 P37268 1 +Broad foot 0.6198908609495853 1.537858066562596 0.1240833222201096 1.0 0.8182357861027015 11 Q7RTS9 1 +Calcinosis 0.7294557960211506 1.5357765454249428 0.1245931940594846 1.0 0.8182357861027015 6 Q14739 1 +Optic nerve hypoplasia 0.5200188292185227 1.5319858410374063 0.1255259287837486 1.0 0.8182357861027015 19 Q9Y5P6,P37268,P30153,P07196,Q9UHX1 5 +Emg chronic denervation signs 0.5558049941358019 1.5300480575082025 0.1260048339027302 1.0 0.8182357861027015 15 Q5TAQ9,P22626,P07602,O95140,Q13510,O60313 6 +Distal sensory impairment 0.4326094438996503 1.5297819736669414 0.1260707050240466 1.0 0.8182357861027015 48 Q5TAQ9,Q9BUK6,Q9NSE4,O95831,Q9NR77,Q9NQ11,Q15120,O95140,O15270,Q8N2K0 10 +Abnormality of the vasculature of the eye 0.3962245260322065 1.5296384477729588 0.1261062471076821 1.0 0.8182357861027015 75 P28070,P17900,Q15555,Q9NSE4,P49327,P38435,Q96S66,Q02978,P21964,O75306,P07602,P34897,P06280,Q9NZ08,P00846,P10619,Q14739,Q13510 18 +Waddling gait 0.4858801420293226 1.5295283734299012 0.1261335106926149 1.0 0.8182357861027015 28 Q9Y5P6,P11047,Q06210,P22626,Q5T8D3,Q4J6C6,P07196,P09651,Q13510,O75340,Q7RTS9,P50402 12 +Visceral angiomatosis 0.9377630787732968 1.5280927936439224 0.1264895004434523 1.0 0.8182357861027015 3 O75874,P48735 2 +Lymphangioma 0.9377630787732968 1.5280927936439224 0.1264895004434523 1.0 0.8182357861027015 3 O75874,P48735 2 +Lower limb pain 0.7550431795492134 1.5261695253016436 0.1269676508509203 1.0 0.8182357861027015 5 P00846 1 +Phenotypic variability 0.4170523749920936 1.5247224879868306 0.1273283302662267 1.0 0.8182357861027015 102 Q9H061,Q9NR77,P07602,P00846,Q70HW3,Q06787,P17900,P00374,Q92733,P07196,Q9Y5P6,Q8NI60,Q06210,O14979,P35270,O95470,O60313,Q15125,Q6P4A7,O95140 20 +Dyschromatopsia 0.6872294309049729 1.5233286600756026 0.1276765002826283 1.0 0.8182357861027015 7 O60313,Q9H6K4 2 +Absent epiphyses 0.6871355598202767 1.5229133281132958 0.127780390837203 1.0 0.8182357861027015 7 O43909,Q7RTS9 2 +Confusion 0.5280201506382762 1.5225928270069589 0.1278606054669195 1.0 0.8182357861027015 18 Q9NQ11,Q16836,Q9NZ08,Q9Y619 4 +Neck muscle weakness 0.5276416657216417 1.5202333423909085 0.1284523402638264 1.0 0.8182357861027015 18 Q99720,Q9Y5P6,P11047,P07602,Q7LG56,P35637 6 +Periventricular white matter hyperintensities 0.6276520771883649 1.5198789208865082 0.1285414091638477 1.0 0.8182357861027015 9 P07602,O75503 2 +Lower limb hyperreflexia 0.5179710934712547 1.5188976111100825 0.1287882704376506 1.0 0.8182357861027015 19 Q14739,Q15041 2 +Abnormal visual field test 0.7532650414824789 1.5188947810565676 0.1287889829068771 1.0 0.8182357861027015 5 P00846 1 +Fatigable weakness of respiratory muscles 0.5272949395193418 1.5180713994908814 0.1289964002590531 1.0 0.8182357861027015 18 Q7LG56,Q92804,P35637 3 +Onion bulb formation 0.6138325149790882 1.5074237266707882 0.1317020808690832 1.0 0.8186096646023245 11 Q5TAQ9,O95140,Q9NR77 3 +Aortic regurgitation 0.4957026540642841 1.5049088171744012 0.1323475211297797 1.0 0.8186096646023245 24 Q6ZXV5,O75844,P28482,O43683,Q6PGP7,O60566,Q9NZ08,Q9UHX1,P49327,Q15645 10 +Decreased muscle mass 0.5249107118519604 1.5031936042301506 0.1327891263418119 1.0 0.8186096646023245 18 O96028,Q06210,Q8NCH0,P31749,Q9Y487,Q7LG56 6 +Abnormality of the pubic bone 0.6435653785903527 1.5005612999714568 0.1334690672909362 1.0 0.8186096646023245 8 Q8IZA0,Q7RTS9 2 +Tongue nodules 0.8893898406973257 1.4994376476562357 0.1337601330322724 1.0 0.8186096646023245 2 P98175 1 +Generalized joint laxity 0.6121431425791278 1.4989227620337084 0.1338936705942848 1.0 0.8186096646023245 11 Q8NCH0,Q9BUK6,Q9Y487 3 +Impaired vibration sensation in the lower limbs 0.5417466735735499 1.49726189635675 0.1343251253771855 1.0 0.8186096646023245 16 P00846,Q9NR77 2 +Centrocecal scotoma 0.8382288912009288 1.493909747857672 0.1351992102793742 1.0 0.8190579159292146 4 P00846,O60313 2 +Inflammatory abnormality of the eye 0.4491812739173628 1.4927435661740804 0.1355043246333425 1.0 0.8190579159292146 40 P14174,P28070,P78536,P04080,P02786,Q9NSE4,P04439,Q15800,P51648,Q9BUR4,Q9NZ08,P01889,P49327,Q14739 14 +Prominent nasolabial fold 0.7464748044538644 1.491087367590871 0.1359385584566697 1.0 0.8190579159292146 5 Q8NCH0 1 +Abnormality of the nasolabial region 0.7464748044538644 1.491087367590871 0.1359385584566697 1.0 0.8190579159292146 5 Q8NCH0 1 +Wide anterior fontanel 0.4979242109273862 1.4902526263569764 0.1361578236531813 1.0 0.8190579159292146 23 Q15125,Q32P28,P20674,Q08J23,O75718,Q9Y487,Q16134,O15111 8 +Cerebral hemorrhage 0.5924061925142966 1.4850475483361725 0.1375312290093586 1.0 0.8240332186768597 12 Q02978,P23786 2 +Hyperconvex nail 0.6400888324694602 1.4841876778572451 0.1377591378501463 1.0 0.8240332186768597 8 Q9Y619 1 +Metaphyseal cupping 0.9256675842294532 1.4831039222331095 0.1380468020979275 1.0 0.8240332186768597 3 Q14739 1 +Easy fatigability 0.4952616273365535 1.472145674486393 0.1409815437830541 1.0 0.8361911692406371 23 Q9Y5P6,Q8IUX1,P61978,P11047,P12235,Q06210,Q9NWM8,O75340,Q7LG56 9 +Abnormal pericardium morphology 0.5718948271869059 1.47001773302573 0.1415569513020282 1.0 0.8374703497614278 13 P14174,Q9NZ08,O15460,Q14108,P04062 5 +Abnormality of pain sensation 0.4791951778149312 1.4666951399857473 0.1424590055498966 1.0 0.8415203909622703 27 P61978,O95831,Q9NR77,Q8NCH0,P07196,O95140,Q06787,O15270 8 +Elevated creatine kinase after exercise 0.7396439435314386 1.4630725263635158 0.143447534561186 1.0 0.8415203909622703 5 O43772 1 +Positional foot deformity 0.4115281121149269 1.46303268541212 0.1434584354300296 1.0 0.8415203909622703 102 P11047,Q15392,Q9NR77,Q8NCH0,Q96AY3,Q9Y487,Q9UJX6,Q7RTS9,P61978,Q9Y619,P98175,P21964,P07196,Q9NWM8,Q9UHX1,Q8NI60,P42356,Q15125,Q9UBM7,P28482 20 +Cytochrome c oxidase negative muscle fibers 0.6158780513437637 1.4622882065934557 0.1436622489147052 1.0 0.8415203909622703 9 P12235,Q9Y2R0,Q7LG56 3 +Parkinsonism with favorable response to dopaminergic medication 0.6151343687470067 1.4586415494429996 0.1446637914470947 1.0 0.8419432662220914 9 Q9NQ11,P07602,P04062 3 +Breech presentation 0.6148683331210162 1.4573367856848922 0.1450234372966232 1.0 0.8429826767204468 9 Q9UBM7,O60313,Q9Y619 3 +Distal upper limb amyotrophy 0.5691985042194407 1.4552762859985793 0.1455927889601234 1.0 0.8441843404711513 13 Q15120,Q9NR77 2 +Macrogyria 0.7100047647705229 1.454395785014541 0.1458366078716422 1.0 0.8445463261820474 6 Q15392 1 +Duplication involving bones of the feet 0.492539166182641 1.4536015567251903 0.1460568050801622 1.0 0.8447707881406653 23 O96028,Q15125,Q9Y263,Q9UBM7,P21964,O43924,O43909,Q14739,P35453 9 +Motor neuron atrophy 0.4836578231635844 1.452391332994435 0.1463928248186476 1.0 0.8456637622278209 25 Q15165,Q99720,Q92804,P22626,Q92734,Q13510,P35637 7 +Incomplete penetrance 0.4705996479211766 1.4491538251847302 0.1472946292771473 1.0 0.846370329065754 30 O14979,Q92733,P00846,O95140,O60313 5 +Abnormal exteroceptive sensation 0.4160780352523477 1.4478646877313006 0.147654897141833 1.0 0.8466517254832198 57 Q5TAQ9,P61978,O95831,Q9H6K4,Q9NR77,Q8NCH0,P07602,Q9NQ11,P07196,O95140,Q9NZ08,O15270,P49327,P06280,Q06787,Q7LG56,O15460 17 +Lissencephaly 0.4180133393260305 1.4461596310937122 0.1481324334966696 1.0 0.8466650232323364 55 O43505,Q15392,P23786,Q86XL3,Q9UJX6,Q9Y487,O95721,P42356 8 +Decreased facial expression 0.4723661288539308 1.4461498088206777 0.1481351878411492 1.0 0.8466650232323364 29 Q9Y5P6,Q9BUK6,P12235,Q9NQ11,P35270,Q06787,P51530,Q7LG56,P04062 9 +Cutaneous photosensitivity 0.486472182476622 1.4411162486405815 0.1495518438258356 1.0 0.8509750116295065 24 Q06136,Q14108,P37268 3 +Abnormal circulating non proteinogenic amino acid concentration 0.6681687101875919 1.4387382290094786 0.1502247036387822 1.0 0.8509750116295065 7 P00846 1 +Cervical spinal canal stenosis 0.913529741760456 1.4379314244022243 0.1504535124240866 1.0 0.8509750116295065 3 O43909 1 +Abnormality of the metacarpal bones 0.4268073646863335 1.4366393946855145 0.1508204837565669 1.0 0.8509750116295065 45 O96028,Q32P28,Q6NUK1,O95613,P35453,Q9UBM7,P31749,O43924,O43909,Q14739,O60828,Q7RTS9,P08236 13 +Hypoglycemic seizures 0.7056704408949492 1.4362048226126822 0.1509440671557143 1.0 0.8509750116295065 6 Q13423,P53985,Q16836,P00367 4 +Stillbirth 0.5997120666184239 1.4361836987856371 0.1509500763057729 1.0 0.8509750116295065 11 Q14739,O75844 2 +Intracranial hemorrhage 0.4898829392716505 1.435479817506812 0.1511504155106533 1.0 0.8509750116295065 23 O75844,Q02978,P23786,P31749,P04062 5 +Tracheal stenosis 0.6664555784921017 1.4311114580777822 0.1523982739268234 1.0 0.8541852573418846 7 O95613,Q15125,O43909,Q9UBM7 4 +Abnormal pelvis bone morphology 0.8213814739025177 1.4288718916568208 0.1530410576647058 1.0 0.8541852573418846 4 Q7RTS9 1 +Perisylvian polymicrogyria 0.7310779018770523 1.427888051318499 0.1533240833470677 1.0 0.8541852573418846 5 P42356 1 +Peripheral axonal degeneration 0.3896211528516863 1.4275485343448564 0.1534218460195524 1.0 0.8541852573418846 78 Q5TAQ9,O95831,P22626,P12235,Q8IV08,Q15067,Q9NQ11,P07602,O60313,P34897,P41440,P00846,Q6DKK2,O95140,Q7LG56,O15270 16 +Abnormal sella turcica morphology 0.6086424363883178 1.4267643512413974 0.153647829852533 1.0 0.8541852573418846 9 O95613,Q96AX1,Q7RTS9,P08236 4 +Progressive gait ataxia 0.5639352069955037 1.4264493766901976 0.1537386695989044 1.0 0.8541852573418846 13 P00846,P07602 2 +Muscle abnormality related to mitochondrial dysfunction 0.4319984790294799 1.4243949846750312 0.1543321652337022 1.0 0.8542203239549915 43 O43676,Q9BUK6,Q9Y2R0,O75648,Q9UBX3,P12235,Q9Y6M9,Q96CU9,Q9NPL8,O75306,Q86Y39,P00846,P51530,Q7LG56,O60313 15 +Aplasia hypoplasia of the capital femoral epiphysis 0.7020696627537683 1.4210781001272643 0.1552940558256585 1.0 0.8542203239549915 6 O43909,Q7RTS9 2 +Cherry red spot of the macula 0.6074175835298636 1.420741313802296 0.1553919772273397 1.0 0.8542203239549915 9 P10619,P07602,P17900 3 +Metaphyseal widening 0.4835078501332936 1.4205539775067506 0.1554464659717584 1.0 0.8542203239549915 24 Q14739,Q7RTS9 2 +Coxa valga 0.5025400557154971 1.4197791352375468 0.1556719911107638 1.0 0.8542203239549915 19 O75844,Q9Y619,Q99575,Q96A33,O43909,P28482,Q9H9E3,P55011 8 +Abnormal clavicle morphology 0.4787260777948464 1.4176492558447795 0.1562931919786914 1.0 0.8542203239549915 25 Q14739,Q96AY3,Q9Y619 3 +Axial dystonia 0.9080433990500324 1.4175093270490302 0.1563340693571391 1.0 0.8542203239549915 3 P35637 1 +Polymicrogyria 0.3884653958499047 1.414614556216087 0.1571815385723283 1.0 0.8549500509261221 78 P37268,O43505,Q15392,P23786,Q01105,P34897,Q9Y487,Q9NZ01,O95721,P42356 10 +Peripheral hypermyelination 0.9070973615041176 1.4139877833013237 0.1573654895068714 1.0 0.8549518309731545 3 Q9NR77 1 +Congenital nystagmus 0.49803188531357 1.4129763809766838 0.1576626689014801 1.0 0.8555620143439416 20 P00846,Q96PZ0,P42858,O75648 4 +Ventricular tachycardia 0.5266286129461186 1.4069099904649909 0.1594540807534672 1.0 0.856726977364211 16 P46976,O43772,P09493,P23786,P0DP25,P41227 6 +Peripheral axonal neuropathy 0.4055787921332416 1.406369787152903 0.1596143469792204 1.0 0.856726977364211 62 Q5TAQ9,O95831,P12235,P22626,Q8IV08,Q15067,Q9NQ11,P07602,P34897,P00846,O15270,O95140,Q7LG56,O60313 14 +Abnormal peripheral myelination 0.4494563869925023 1.4041530815956689 0.1602732697834743 1.0 0.857688038593769 36 Q5TAQ9,Q9NR77,P07602,P00846,O95140,Q7LG56 6 +Symptomatic seizures 0.6602751657425964 1.4035661377711672 0.1604480845393412 1.0 0.857688038593769 7 Q13423,P53985,Q16836,P00367 4 +Progressive spastic quadriplegia 0.6032076394100118 1.4000191437620109 0.1615075858504262 1.0 0.8593764996549351 9 P17900,Q9Y263,Q9NQ11,P07602,O43681 5 +Abnormal size of the clitoris 0.4987945236339894 1.3955950490903406 0.1628364741788084 1.0 0.8597092743108519 19 Q8IWV7,P53701,Q9Y619 3 +Respiratory failure 0.3873190132263225 1.3937885231343043 0.1633814748931465 1.0 0.8597092743108519 72 Q5XKP0,Q9Y5P6,P53701,Q15165,Q92804,Q9Y619,P23786,O75306,P07602,Q92734,P09651,Q70HW3,Q13510,P35637 14 +Hypoplastic iliac wing 0.8632401562969495 1.3920824879834064 0.1638974205440246 1.0 0.8597092743108519 2 Q7RTS9 1 +Abnormality of epiphysis morphology 0.4054473465595204 1.391317586948848 0.1641291430664706 1.0 0.8597092743108519 61 O96028,Q15125,Q9Y619,O95613,O95831,P38435,Q9UBM7,Q7LGA3,Q9Y2B2,Q02224,O43909,Q14739,Q9HC07,Q7RTS9 14 +Abnormality of mouth shape 0.388870323689969 1.3891112033669817 0.1647989375137177 1.0 0.8597092743108519 71 O96028,Q15125,P61978,P11047,Q6DKJ4,Q96PZ0,Q86XL3,P31749,P34897,P30153,O60566,O43909,P04062 13 +Pulmonary embolism 0.810827067669174 1.3880780677163784 0.1651132742863099 1.0 0.8597092743108519 4 P49327,P31749,Q9NZ08 3 +Abnormality of earlobe 0.4664782539313627 1.388043707927795 0.1651237361757525 1.0 0.8597092743108519 28 P53701,P98175,Q7LGA3,Q15392,Q02224,P21964,P28482 7 +Cold induced muscle cramps 0.8988958791267174 1.3834596968785813 0.1665239569954901 1.0 0.8597092743108519 3 Q9NR77 1 +Bradykinesia 0.4736039108868275 1.3814577376449515 0.1671382637133442 1.0 0.8597092743108519 25 P42858,P12235,Q9NQ11,P35270,Q6DKK2,Q06787,Q7LG56,P04062 8 +Agitation 0.4493957826336573 1.381345574546088 0.1671727315780431 1.0 0.8597092743108519 35 Q6PJG6,Q15165,Q92804,P42858,P48449,P42892,P09651,P35637,P04062 9 +Paresthesia 0.4690914110453064 1.3810829968239309 0.1672534429370296 1.0 0.8597092743108519 26 Q9H6K4,Q9NR77,P07196,Q9NZ08,O15460,O95140,Q7LG56 7 +Myoclonic seizure 0.412631214980495 1.3776663475862925 0.1683063259824173 1.0 0.8597092743108519 53 Q6PJG6,Q9Y619,Q01105,P07602,O60566,Q9UJX6,O75503,P00846,O43909,P04062 10 +Serositis 0.4852642730240378 1.3770788289847171 0.1684878774069895 1.0 0.8597092743108519 22 P14174,Q0IIM8,O15460,Q9NZ08 4 +Premature rupture of membranes 0.6911908053072382 1.375302385241041 0.1690377173479063 1.0 0.8597092743108519 6 O75844 1 +Babinski sign 0.3985329426152682 1.374837001275597 0.1691819839688213 1.0 0.8597092743108519 95 Q99720,O95831,P42858,Q9H6K4,Q9NR77,Q15067,P07602,Q9NQ11,P34897,P07196,P41440,P00846,Q6DKK2,O95140,O60313,Q8N2K0,P35637 17 +Abnormal autonomic nervous system physiology 0.4457834488376403 1.3746412298408464 0.1692426996898688 1.0 0.8597092743108519 36 Q6PJG6,Q15067,Q6Y7W6,P07602,P42892,Q99996,P41440,P48643,P06280,P0DP25,Q06787,P04062 12 +Vascular neoplasm 0.4262090180084582 1.3739113777242862 0.1694691969664836 1.0 0.8597092743108519 43 Q02978,Q9UBM7,Q7LGA3,O75874,P31749,Q9UJX6,P48735,Q9UHX1,O43909,P10619 10 +Distal sensory impairment of all modalities 0.717809867629384 1.3732887004216832 0.1696626139779675 1.0 0.8597092743108519 5 P48643,O15269,O95140,O15270 4 +Abnormal muscle fiber type distribution 0.5711034538594463 1.372940266488855 0.1697709172748758 1.0 0.8597092743108519 12 Q9Y5P6,P11047,Q06210,O75340,P51114 5 +Glomerulopathy 0.592234491409059 1.3713625936609015 0.1702619521293229 1.0 0.8597092743108519 10 P49327,P06280,Q14108,Q9NZ08 4 +Brisk reflexes 0.4796037077366009 1.365091862221307 0.1722241794327685 1.0 0.8597092743108519 23 Q99720,Q8NI60,Q9NQ11,Q5JRX3,P35637 5 +Abnormal metacarpal morphology 0.4443049825536088 1.362740687446778 0.1729642499161006 1.0 0.8597092743108519 36 Q14739,Q7RTS9,Q32P28 3 +Pathologic fracture 0.5025485060399053 1.3627248140717103 0.1729692543863052 1.0 0.8597092743108519 18 P22626,Q13126,Q14108,P04062 4 +Keratitis 0.5848895175530354 1.360973067174103 0.1735222009042756 1.0 0.8597092743108519 11 Q9NSE4,Q14739,Q9NZ08 3 +Monotonic speech 0.7147206341025455 1.3605609438434736 0.1736524811520783 1.0 0.8597092743108519 5 P04062 1 +Spastic paraparetic gait 0.8926136023849963 1.360079499990002 0.1738047675156697 1.0 0.8597092743108519 3 Q15041 1 +Distal lower limb amyotrophy 0.5338960596143036 1.357830136515139 0.1745175899020743 1.0 0.8597092743108519 14 P06753,Q8TD16,Q9NR77,P07196,Q92734,Q15120,O95140 7 +Morning myoclonic jerks 0.8542230237451045 1.3551118541401728 0.1753819224649015 1.0 0.8597092743108519 2 Q14108 1 +Aplasia hypoplasia of the optic nerve 0.4697519555962199 1.3541708661500804 0.1756818714610728 1.0 0.8597092743108519 25 Q9Y5P6,P37268,P30153,P07196,Q9UHX1,O95721 6 +Prominent sternum 0.8907762291663643 1.3532426488571037 0.1759781243789806 1.0 0.8597092743108519 3 Q7RTS9 1 +Myoclonic spasms 0.6486220817993832 1.3515084967608435 0.1765325999632563 1.0 0.8597092743108519 7 P00846,P31749 2 +Basal ganglia gliosis 0.5930059589592122 1.3496790582643767 0.1771189525852223 1.0 0.8597092743108519 9 P00846 1 +Unusual infection by anatomical site 0.5248607056308049 1.349146235801414 0.1772899998105075 1.0 0.8597092743108519 15 P49327,Q14739,O15460,Q9NZ08 4 +Abnormal cartilage morphology 0.5664965251136997 1.3485713530363024 0.1774746872293642 1.0 0.8597092743108519 12 O75874,P48735,Q9UHX1 3 +Enlarged thorax 0.4910751927227949 1.3456078429202072 0.1784290209743277 1.0 0.8597092743108519 19 Q14739,Q7RTS9,Q32P28 3 +Exaggerated cupid s bow 0.6840535763127723 1.3452155497995533 0.1785556360588085 1.0 0.8597092743108519 6 Q6DKJ4,P11233 2 +Arthrogryposis multiplex congenita 0.4342128223866766 1.3446704249977968 0.1787316895014277 1.0 0.8597092743108519 39 O75844,Q15392,Q8NCH0,Q96AY3,P04062 5 +Extramedullary hematopoiesis 0.7994843900517369 1.3442127014453848 0.17887961555346 1.0 0.8597092743108519 4 Q14739 1 +Thin lower lip vermilion 0.8515178839795612 1.3440286886377826 0.1789391100485511 1.0 0.8597092743108519 2 Q7LGA3 1 +Hyperthyroidism 0.5655495421222476 1.3435570762047684 0.1790916576260803 1.0 0.8597092743108519 12 Q9BUK6,P12235,P31749,Q06787,Q7LG56 5 +Abnormal electroretinogram 0.4417550594657615 1.342187658711938 0.1795351569836363 1.0 0.8600801152675364 36 P50897,Q15555,P12235,Q15067,O43924,P00846,Q96S66 7 +Emg axonal abnormality 0.7985324406127765 1.34053060934066 0.1800728997885863 1.0 0.8612859663507051 4 Q9NQ11,Q15120 2 +Abnormality of the clitoris 0.4795231903906992 1.3382230667163506 0.180823731923472 1.0 0.8613595788298073 22 Q8IWV7,P53701,Q9Y619 3 +Lower limb amyotrophy 0.4985965128673623 1.3377368529070015 0.180982233086784 1.0 0.8613595788298073 18 P06753,Q8TD16,Q9NR77,P07196,Q92734,Q15120,O95140 7 +Thick cerebral cortex 0.7090516988809645 1.3371920973160225 0.1811599408254345 1.0 0.8613595788298073 5 Q9Y487 1 +Bruising susceptibility 0.448671434992632 1.3352491430418447 0.1817948175931651 1.0 0.8622755874063551 33 Q86YV9,P38435,P28482,Q8NCH0,Q13126,Q9NWM8,P49257,P49327,Q14108,P04062 10 +Abnormality of the peripheral nervous system 0.4107982391679241 1.3333638307745397 0.1824124358799081 1.0 0.8622755874063551 118 Q5TAQ9,Q9NR77,Q15067,P07602,O15360,Q9UJX6,Q06787,Q9Y619,P21964,P07196,Q92734,P41440,O95721,Q7LG56,P04062,Q99720,Q9Y2B2,P42892,P06280,O15270,O60313,Q8N2K0,Q9NQZ5,Q6PJG6,Q15125,O95831,Q9UBM7,Q6Y7W6,Q15120,O95140 30 +Ventricular arrhythmia 0.4150417460555956 1.3312570871638725 0.1831044330962654 1.0 0.8634198953814681 45 O43772,P23786,P09493,O75306,P42892,P00846,Q7LG56 7 +Pulmonary fibrosis 0.4884679439835215 1.3286819034678317 0.1839529377585342 1.0 0.8634198953814681 19 P14174,Q8IZA0,P09601,P04062 4 +Limited wrist movement 0.6799412450812032 1.3278624531113623 0.1842235505532685 1.0 0.8634198953814681 6 Q9H6K4,O75844 2 +Eeg with polyspike wave complexes 0.6430655422885079 1.3266350105658238 0.1846294486559871 1.0 0.8634198953814681 7 P42356,Q9Y2B2,Q14108 3 +Schizophrenia 0.505005182107473 1.3253004115411149 0.1850715325581411 1.0 0.8634198953814681 17 P04062,Q9BUK6,Q92766,P21964,Q6Y7W6,P07602,O76024,P16615,O43681 9 +Abnormality of carpal bone ossification 0.6788872662279557 1.3234129748180847 0.1856980793067344 1.0 0.8646102572521556 6 Q15125 1 +Hypopigmented skin patches 0.4514325008207831 1.3212342312933063 0.1864232757429424 1.0 0.8662542633324752 31 Q8IZA0,P53701,Q15125,P21964,O15360,P07602,P31749,P49327 8 +Sclerocornea 0.5818022092091546 1.3190188132708942 0.1871628229894719 1.0 0.8663695536368556 10 O96028,P53701,Q9UBM7 3 +Optic disc pallor 0.4064329485120842 1.318722438487279 0.1872619224106406 1.0 0.8663695536368556 53 Q9H061,O43676,O95831,Q96CU9,Q9H6K4,Q9NPL8,O75306,P00846,Q96S66,O95140,O60313 11 +Abnormal scapula morphology 0.404753365332624 1.3187157473603142 0.1872641601831137 1.0 0.8663695536368556 55 P62857,Q9Y5P6,P11047,Q9Y619,P07196,Q9Y487,Q14739,Q7RTS9,O60313 9 +Abnormal foot bone ossification 0.8806850965793531 1.3157072356323507 0.188272324714434 1.0 0.8663695536368556 3 Q14739 1 +Quadriceps muscle weakness 0.7037246496286758 1.3152195939474751 0.1884361118352155 1.0 0.8663695536368556 5 O95140,Q7LG56 2 +Generalized hyperkeratosis 0.7037018174165509 1.315125393903776 0.188467763474732 1.0 0.8663695536368556 5 O75844 1 +Dicarboxylic aciduria 0.4758416174736875 1.3132461841552163 0.1891000061063372 1.0 0.8663695536368556 22 O43772,P48735,P23786 3 +Hypoplasia of the femoral head 0.8437030357679577 1.312036112759705 0.189507950118771 1.0 0.8663695536368556 2 Q99575 1 +Increased circulating antibody level 0.4856998875764541 1.3106894885749374 0.1899626913979648 1.0 0.8667557182489657 19 P28070,P78536,O43909,P49327,Q14108,P04062 6 +Osteolysis 0.4478026998230328 1.3103773545165838 0.1900682105524471 1.0 0.8667557182489657 32 O75844,P22626,Q9Y2B2,O75874,O60566,P48735,P09651,Q14108,P04062 9 +Orthostatic hypotension 0.5254337468400014 1.3090532805405863 0.1905163032840464 1.0 0.8679490294427792 14 P04062,Q6Y7W6,Q9NZJ7,P07602,Q04446,O43681 6 +Limited elbow extension 0.5423744140398258 1.307703277832213 0.190973971141207 1.0 0.8683347750326759 13 P28482,Q7RTS9,Q9H6K4 3 +Weakness of muscles of respiration 0.4373703452545248 1.306764273677634 0.1912927821584606 1.0 0.8689357987607736 36 P06753,Q8TD16,Q13148,O95831,P12235,Q06210,P22626,Q7RTS9,Q15067,O95140,Q7LG56,P09651,Q13510,P50402 14 +Gait ataxia 0.3794574361240274 1.303776652653433 0.1923097452701376 1.0 0.8717451658572395 79 Q6PJG6,P42858,P12235,Q8IV08,Q9NR77,Q9NQ11,P07602,O15118,P07196,P41440,P00846,Q7LG56,Q14108 13 +Abnormality of chorioretinal pigmentation 0.70067464487757 1.3026344127054876 0.1926996033734656 1.0 0.8717451658572395 5 Q9Y619 1 +Abnormal ilium morphology 0.4775868672368316 1.3008634391080014 0.1933052025452275 1.0 0.8717451658572395 21 O43909,Q7RTS9,O95831,O95613 4 +Leg muscle stiffness 0.8763259501575889 1.2995020457216124 0.1937716918632492 1.0 0.8717451658572395 3 P00846 1 +Apraxia 0.3824807147551696 1.298990218468985 0.1939472860489974 1.0 0.8717451658572395 70 O75648,Q9Y619,P42858,Q96PZ0,P28482,Q7LGA3,P35637,Q9NQ11,O43924,P35270,Q6DKK2,P42356,P04062 13 +Abnormal larynx physiology 0.4924460852962557 1.2987593202830392 0.1940265392398841 1.0 0.8717451658572395 18 Q15165,Q13510,Q92804,P35637 4 +Left ventricular systolic dysfunction 0.6367910164165187 1.298512260337819 0.1941113660959497 1.0 0.8717451658572395 7 Q7LG56,O75844 2 +Abdominal aortic aneurysm 0.7873900681380727 1.2974319930843037 0.1944825904494518 1.0 0.8717451658572395 4 O15460 1 +Arthritis 0.4174598463962 1.2972049969338209 0.1945606618710456 1.0 0.8717451658572395 43 P14174,P28070,O75844,P10321,P21964,Q9NZ08,P49327,Q14739,Q13510,O15460,Q14108,P04062 12 +Hammertoe 0.4733424360140391 1.2962652973374515 0.1948841000184018 1.0 0.8717451658572395 22 Q99720,Q5TAQ9,Q9UBM7,Q9NR77,O95140 5 +Telangiectasia 0.4387162690458948 1.2962159979525785 0.1949010794098833 1.0 0.8717451658572395 35 Q8IZA0,P31749,P00846,P10619,Q14739 5 +Recurrent hand flapping 0.8746524068489037 1.2932824653524575 0.1959133829490871 1.0 0.8717451658572395 3 P55795 1 +Retinal telangiectasia 0.6982796212426872 1.292749760922738 0.1960976212531395 1.0 0.8717451658572395 5 P00846 1 +Hydrocele testis 0.671622149135091 1.292722898631021 0.1961069150627614 1.0 0.8717451658572395 6 Q9UBX3,P31749,Q9UJX6 3 +Dysmetria 0.3955215155999621 1.2913179602728144 0.1965934452818489 1.0 0.8725825369230589 61 Q8N183,Q8IV08,Q96D71,Q9NPL8,P34897,Q8N0X7,Q06787,Q9BUK6,O75503,P41440,Q6DKK2,Q7LG56,Q96TA2,P42356,O60313,Q8N2K0,Q6PJG6,Q5T8D3,Q6P4A7,Q5JRX3 20 +Abnormal vertebral morphology 0.4061926471036886 1.288108727525656 0.1977081176999313 1.0 0.8734568837681054 117 Q9NSE4,Q8NCH0,Q96AY3,P48735,Q9UJX6,Q14739,Q7RTS9,Q14108,Q32P28,Q9Y619,Q9UHX1,O43909,P04062,Q6DKJ4,O75874,P31749,P10619,Q15125,O95831,Q9UBM7 20 +Capillary hemangioma 0.5700174376144336 1.285118727139224 0.1987507983722432 1.0 0.8734568837681054 11 O43909,P31749,Q9UBM7,Q9UHX1 4 +Psoriasiform dermatitis 0.6961542277101829 1.283976549970797 0.199150160615056 1.0 0.8734568837681054 5 Q15800,P78536,P10321 3 +Spastic tetraparesis 0.4535106981701233 1.2799878744092867 0.2005494004499139 1.0 0.8734568837681054 27 P00846,Q7RTS9 2 +Abnormality of the shoulder girdle musculature 0.4364411890085312 1.278005471762671 0.2012474969549145 1.0 0.8734568837681054 35 Q9Y5P6,P46976,P11047,P12235,Q06210,O14979,P07602,P07196,Q9Y487,Q7LG56,O75340,P50402,O60313 13 +Hemangiomatosis 0.7823626561154559 1.2779888834019435 0.2012533459598064 1.0 0.8734568837681054 4 O75874,P48735 2 +Erlenmeyer flask deformity of the femurs 0.8701473075739852 1.27654538785735 0.2017627930225516 1.0 0.8734568837681054 3 P07602 1 +Osteoarthritis 0.5780714568570625 1.2756940567389892 0.2020636903313235 1.0 0.8734568837681054 9 Q14108,O75844 2 +Abnormality of facial musculature 0.3769517737727235 1.275429122879964 0.2021573961391696 1.0 0.8734568837681054 79 P11047,P12235,Q9NQ11,P34897,P30153,Q9BUK6,P07196,Q9UHX1,Q13510,P51530,Q7LG56,P04062,Q9Y5P6,Q06210,P31749,Q96TA2,P35270,O75340,P42356,O60313 20 +Abnormal erythrocyte sedimentation rate 0.572805434869534 1.2737413719322723 0.2027550890329381 1.0 0.8734568837681054 10 P14174,P15260,P28070,O15460 4 +Hand polydactyly 0.4280583953987179 1.2724936081117604 0.2031977937082407 1.0 0.8734568837681054 38 Q15125,P98175,Q9UBM7,P21964,Q15067,O43924,Q9UHX1,O43909,Q14739 9 +Tapered finger 0.4255644295804855 1.2722284864407707 0.203291949068652 1.0 0.8734568837681054 39 Q15555,Q9NSE4,Q9Y4W2,P23786,Q8NCH0,Q06136,P42892 7 +Symphalangism affecting the phalanges of the hand 0.780599832152894 1.2711722380273118 0.2036673807247888 1.0 0.8734568837681054 4 P35453,O60828 2 +Rheumatoid factor positive 0.6930417601529485 1.2711268978827233 0.2036835076600134 1.0 0.8734568837681054 5 Q13546,P15260,P49327 3 +Vocal cord paralysis 0.4763677436202899 1.2704057436716982 0.2039401383734889 1.0 0.8734568837681054 20 Q02978,Q9NR77 2 +Abnormality of the larynx 0.4011099675009126 1.2678756571064471 0.2048423585137331 1.0 0.8734568837681054 53 Q15165,Q92804,O95613,Q9UBM7,P21964,P07602,Q9UHX1,O43909,Q14739,Q13510,P35637 11 +Shoulder girdle muscle weakness 0.5182866780516792 1.2677353694257023 0.2048924694069958 1.0 0.8734568837681054 14 P06753,P46976,P12235,O14979,P07602,Q7LG56 6 +Abnormal midbrain morphology 0.5762586649146307 1.2666924444553194 0.2052652826658965 1.0 0.8734568837681054 9 P04062 1 +Resting tremor 0.4723168114890871 1.2655284294738955 0.2056819638408673 1.0 0.8734568837681054 21 P12235,Q9H6K4,Q9NQ11,P07602,Q06787,Q7LG56,P04062 7 +Absent toenail 0.5936675798620348 1.263772644278113 0.2063116425318547 1.0 0.8734568837681054 8 Q14739 1 +Erythroderma 0.5657015063347863 1.2630403003723314 0.2065746969499793 1.0 0.8734568837681054 11 P48449,Q15125 2 +Generalized muscle weakness 0.4314328711206949 1.2586375597833854 0.2081612740493434 1.0 0.8734568837681054 36 Q15165,Q92804,P11047,O95831,P12235,Q9NQ11,P35637 7 +Joint contracture of the hand 0.4000900425069807 1.258109871408716 0.20835202379944 1.0 0.8734568837681054 53 Q8IZA0,O75844,Q9Y619,Q6DKJ4,Q15392,Q9NR77,P42892,P07196,Q9UJX6 9 +Protrusio acetabuli 0.8647505825453106 1.2565082484364862 0.2089317572472206 1.0 0.8734568837681054 3 Q96AY3 1 +Abnormality of chromosome segregation 0.7761783616658929 1.2540777947055042 0.209813730512028 1.0 0.8734568837681054 4 Q14739,O60566 2 +Dermal atrophy 0.4464768554792639 1.2536004026540355 0.2099872848043078 1.0 0.8734568837681054 29 Q8NCH0,P53701,Q15392,O75844 4 +Hemivertebrae 0.5158137219511308 1.2534147793538768 0.2100547955891087 1.0 0.8734568837681054 14 Q15125,Q9Y619 2 +Episodic vomiting 0.562861540999938 1.2484977707929257 0.2118488242596505 1.0 0.8734568837681054 11 P00846 1 +Color vision defect 0.5471564293354934 1.2458490658946737 0.2128198122733082 1.0 0.8734568837681054 12 O95140,O60313,Q9H6K4 3 +Hyporeflexia of lower limbs 0.5467526333370716 1.2436978056562618 0.2136108039197068 1.0 0.8734568837681054 12 Q9NR77 1 +Fatigable weakness of bulbar muscles 0.4836018554427662 1.2425325555597346 0.2140401365670405 1.0 0.8734568837681054 18 Q15165,Q9Y5P6,Q92804,P09651,P35637 5 +Aplasia hypoplasia affecting the fundus 0.446698941550986 1.242086071642863 0.214204806953115 1.0 0.8734568837681054 28 Q86YV9,Q9Y5P6,P37268,P30153,P07196,Q9UHX1,O95721 7 +Raynaud phenomenon 0.6238173762074651 1.2402618081991144 0.2148785736741785 1.0 0.8734568837681054 7 Q14739 1 +Dolichocephaly 0.4165601687087109 1.239923802622086 0.2150035789524185 1.0 0.8734568837681054 41 P61978,Q4J6C6,O15360,P31749,P42356,Q9UJX6,O95721,Q7RTS9 8 +Absent nipple 0.8256687706642603 1.2383929064777155 0.2155704095809665 1.0 0.8734568837681054 2 P10586 1 +Absent distal phalanges 0.8256687706642597 1.238392906477714 0.2155704095809671 1.0 0.8734568837681054 2 O15111 1 +Calvarial skull defect 0.570532886224324 1.238233658312171 0.2156294346663942 1.0 0.8734568837681054 9 Q14739 1 +Abnormal cell proliferation 0.7714562492364654 1.235826776538364 0.2165229595777504 1.0 0.8734568837681054 4 P17812 1 +Decreased specific antibody response to protein vaccine 0.8247670574090631 1.2347190566676876 0.2169350810312846 1.0 0.8734568837681054 2 P17812 1 +Bradycardia 0.5290340699050762 1.2337640763818436 0.2172908292543804 1.0 0.8734568837681054 13 Q6PJG6,P47985,O43772,P0DP25,O75880 5 +Prominent metopic ridge 0.5645459008764973 1.232075723208839 0.2179207990334202 1.0 0.8734568837681054 10 P28482,P30153 2 +Single fiber emg abnormality 0.8577871316897145 1.2306776641504078 0.2184434451404238 1.0 0.8734568837681054 3 Q06210,Q9Y5P6 2 +Muscle fiber tubular inclusions 0.8577871316897145 1.2306776641504078 0.2184434451404238 1.0 0.8734568837681054 3 Q06210,Q9Y5P6 2 +Eeg with spike wave complexes 0.5044711164847392 1.2286199139922325 0.219214345534136 1.0 0.8734568837681054 15 Q9Y2B2,O75503,Q14108,P42356,Q9NQZ5 5 +Congenital ichthyosiform erythroderma 0.6563398012910945 1.228074004094967 0.2194191886641125 1.0 0.8734568837681054 6 Q15125 1 +Dysostosis multiplex 0.5677025319489345 1.224151820771509 0.220894960308889 1.0 0.8734568837681054 9 P04066,Q96AX1,P10619,P54802,P08236 5 +Joint laxity 0.3707258891073512 1.224020772009549 0.2209443916421591 1.0 0.8734568837681054 77 Q9Y5P6,Q9BUK6,Q32P28,Q9Y619,Q8IWV7,Q06210,P55795,Q8NCH0,Q96AY3,Q9Y487,Q9UJX6,P28482,Q9HC07,Q06787,Q9UHX1 15 +Impaired distal tactile sensation 0.7681283887171613 1.222969024058483 0.2213413961208068 1.0 0.8734568837681054 4 O15270 1 +Lewy bodies 0.6548711817632916 1.2218563492376384 0.2217619549735754 1.0 0.8734568837681054 6 P04062 1 +Severe lactic acidosis 0.8552036267541843 1.2211019426771874 0.2220474242569849 1.0 0.8734568837681054 3 Q70HW3 1 +Poor fine motor coordination 0.6192791793904767 1.2198587932365867 0.2225184090583467 1.0 0.8734568837681054 7 P42858,O95140 2 +Bladder neoplasm 0.5665527743554476 1.2184289310715612 0.2230610165141335 1.0 0.8734568837681054 9 P31749,O60566,O43683 3 +Corneal dystrophy 0.6802045728038657 1.218114465955009 0.2231804773801229 1.0 0.8734568837681054 5 P06280,P12235,Q3LXA3,Q13868 4 +Depletion of mitochondrial dna in muscle tissue 0.68010302491921 1.2176950796217625 0.2233398675611058 1.0 0.8734568837681054 5 P12235,Q7LG56 2 +Abnormality of the pulmonary veins 0.5839008226746957 1.2170590867433135 0.2235817356620186 1.0 0.8734568837681054 8 Q15392 1 +Focal myoclonic seizure 0.5662275079052784 1.2168096700997424 0.2236766399390455 1.0 0.8734568837681054 9 O75503 1 +Ureteral duplication 0.6535440585602912 1.216237187533348 0.223894581358969 1.0 0.8734568837681054 6 P23786,O75844 2 +Abnormal oral physiology 0.3796235084156091 1.213722832768212 0.2248535822991455 1.0 0.8734568837681054 67 Q15165,P11047,Q92804,P55795,Q9NR77,O43909,Q14739,P42356,O15460,P35637 10 +Abnormality of the calf 0.3878067246428259 1.21304240239217 0.2251136092992183 1.0 0.8734568837681054 61 Q32P28,Q9Y619,Q9NR77,Q13126,Q7RTS9 5 +Urinary bladder sphincter dysfunction 0.5602619575357924 1.210432149272703 0.2261131117877723 1.0 0.8734568837681054 10 P22626,Q06787,Q9NR77 3 +Ureteropelvic junction obstruction 0.7647865778528529 1.2100617795225548 0.2262551877164886 1.0 0.8734568837681054 4 Q9UBM7,Q9UJX6 2 +Glioma 0.4939435399150337 1.2094696301370385 0.2264824718825104 1.0 0.8734568837681054 16 O75874,P48735 2 +Submucous cleft of soft and hard palate 0.4532990689161934 1.2091153348765031 0.2266185385721373 1.0 0.8734568837681054 24 Q15392,O75844,Q9Y619 3 +Subcapsular cataract 0.6167176600532607 1.2083375884849468 0.2269174356597521 1.0 0.8735627542365045 7 Q8N2K0 1 +Spinal cord compression 0.5813872325228094 1.2050232541277406 0.2281943249048823 1.0 0.8735627542365045 8 O43909,P51530 2 +Abnormality of female external genitalia 0.4198418431494062 1.2040753640051445 0.2285604509780718 1.0 0.8735627542365045 38 P53701,Q08J23,Q9Y619,Q8IWV7,Q6DKJ4,Q9UBM7,Q15392 7 +Retinal hamartoma 0.5636683898669561 1.204065902429644 0.2285641076539877 1.0 0.8735627542365045 9 Q02978 1 +Mitral valve calcification 0.7623095584670978 1.2004978819721617 0.229946034731169 1.0 0.8761282632637668 4 O75844 1 +Cardiac valve calcification 0.7623095584670978 1.2004978819721617 0.229946034731169 1.0 0.8761282632637668 4 O75844 1 +Retinopathy 0.4392348031463161 1.1992402742682369 0.2304345312384472 1.0 0.8772716087049962 29 Q15555,P51648,O75306,Q9NZ08,P00846,P49327 6 +Abnormal sacrum morphology 0.4191480009373773 1.1982823205499709 0.2308071268968747 1.0 0.877972208195955 38 O96028,P53701,Q15125,P61978,Q08J23,Q6DKJ4,Q03164,Q15056,P01889,Q9UJX6,O43909,Q14739 12 +Anarthria 0.6141564388329601 1.1968145254524871 0.2313788553770486 1.0 0.8794285311310517 7 Q99720,P35637 2 +Decreased plasma carnitine 0.5374853789768543 1.194262317682626 0.2323753729367008 1.0 0.8796873388746287 12 Q16836,P23786,O75880,O43772 4 +Ovarian neoplasm 0.4572058510062379 1.186164641199259 0.2355572868933435 1.0 0.8835096861819387 22 P31749,O75874,P48735 3 +Abnormal sternal ossification 0.6723899633678728 1.1858428340826477 0.2356843721998305 1.0 0.8835096861819387 5 Q9Y619 1 +Papule 0.4635254948898769 1.1852409023646082 0.2359222121350961 1.0 0.8835096861819387 20 P31749,P38435,O75844,Q9NZ08 4 +Endocarditis 0.672068700647536 1.1845162930839466 0.2362087505460679 1.0 0.8835096861819387 5 P04062,Q9NZ08 2 +Abnormal greater sciatic notch morphology 0.6107240785877148 1.1813677548260149 0.2374566618493379 1.0 0.8835096861819387 7 Q7RTS9 1 +Short sternum 0.844211856736292 1.180415480542114 0.2378350079029405 1.0 0.8835096861819387 3 P98175 1 +Upper limb amyotrophy 0.4891390439849342 1.180247064433685 0.2379019652258138 1.0 0.8835096861819387 16 Q15120,Q9NR77 2 +Recurrent aspiration pneumonia 0.6447754919840243 1.179100125818126 0.2383583085232916 1.0 0.8835096861819387 6 Q13510,P04062 2 +Retinal thinning 0.8106402164111833 1.1772903663844565 0.2390796307019478 1.0 0.8835096861819387 2 P51648 1 +Abnormal optical coherence tomography 0.8106402164111688 1.1772903663843972 0.2390796307019713 1.0 0.8835096861819387 2 Q96S66 1 +Photoreceptor layer loss on macular oct 0.8106402164111688 1.1772903663843972 0.2390796307019713 1.0 0.8835096861819387 2 Q96S66 1 +Abnormality of lower limb epiphysis morphology 0.4652722044878329 1.1772602496495408 0.2390916474466196 1.0 0.8835096861819387 19 O43909,Q7LGA3,Q7RTS9,O95831 4 +Recurrent pharyngitis 0.8103396453261063 1.1760713510049876 0.2395663650537565 1.0 0.8835096861819387 2 O15460 1 +Glossitis 0.8103396453261063 1.1760713510049876 0.2395663650537565 1.0 0.8835096861819387 2 O15460 1 +Gastrointestinal infarctions 0.8103396453261063 1.1760713510049876 0.2395663650537565 1.0 0.8835096861819387 2 O15460 1 +Y shaped metacarpals 0.8094379320709328 1.1724150874750745 0.2410304449996392 1.0 0.8835096861819387 2 O43924 1 +Abnormality of the middle phalanx of the 5th finger 0.8094379320709264 1.1724150874750492 0.2410304449996494 1.0 0.8835096861819387 2 Q9UHX1 1 +Decreased number of peripheral myelinated nerve fibers 0.472475846135356 1.171535177303861 0.2413837266545417 1.0 0.8835096861819387 18 Q7LG56,P07196,O95140,Q9NR77 4 +Abnormality of adrenal morphology 0.4401629246524691 1.1714059814512223 0.2414356291296484 1.0 0.8835096861819387 26 Q02978,O75874,P48735 3 +Chordee 0.6082400199471244 1.170185951428181 0.2419261450909271 1.0 0.8835096861819387 7 P48651,P53701 2 +Polydactyly 0.391973500923889 1.1683337466114232 0.2426721680708146 1.0 0.8835096861819387 51 Q15125,P61978,P98175,Q9UBM7,Q15067,P21964,O43924,P30153,Q9UHX1,O43909,Q14739 11 +Kyphoscoliosis 0.3793906522433778 1.1653875468823285 0.2438621558126679 1.0 0.8835096861819387 64 O75844,Q9NR77,Q8NCH0,P31749,Q96AY3,Q9Y487,Q9NWM8,O43909,P51530 9 +Decreased proportion of cd4 positive helper t cells 0.6412122626213153 1.1640058272335547 0.2444216502659393 1.0 0.8835096861819387 6 O43909 1 +Bowing of the legs 0.3902577921854873 1.1636032620900991 0.2445848288275984 1.0 0.8835096861819387 53 Q9Y619,Q7RTS9,Q32P28,Q9NR77 4 +Paralysis 0.3907760164574249 1.1624392958983998 0.2450570691447404 1.0 0.8835096861819387 52 Q15165,Q92804,Q02978,P35637,Q9NR77,P42356,P04062 7 +Absent brainstem auditory responses 0.7515789473684226 1.159104934944323 0.2464134145752661 1.0 0.8835096861819387 4 P07196,Q13724,O60313 3 +Abnormal motor nerve conduction velocity 0.4423046114460712 1.1581731334929162 0.2467933898601992 1.0 0.8835096861819387 25 Q99720,Q5TAQ9,Q9NR77,O95140,Q7LG56 5 +Abnormality of pulmonary circulation 0.4317891528637246 1.156357508625245 0.2475349543645106 1.0 0.8835096861819387 30 Q8IZA0,O75844,P11047,P31749,Q9NZ08,P49327,Q14108,P04062 8 +Ulnar deviation of the hand or of fingers of the hand 0.5148179340240329 1.1546567719285392 0.248231008264129 1.0 0.8835096861819387 13 Q14739,Q9UBM7 2 +Bifid scrotum 0.6047814600454194 1.1546144236815064 0.2482483574224487 1.0 0.8835096861819387 7 Q9UBM7,O60566 2 +Ulnar claw 0.75035990590802 1.154407116064262 0.2483332990981603 1.0 0.8835096861819387 4 Q9NR77 1 +Subvalvular aortic stenosis 0.6645938683707144 1.1536582485806204 0.2486403074594418 1.0 0.8835096861819387 5 Q15645,O60566 2 +Abnormal left ventricular outflow tract morphology 0.6645938683707144 1.1536582485806204 0.2486403074594418 1.0 0.8835096861819387 5 Q15645,O60566 2 +Nemaline bodies 0.7500520864874078 1.1532210386364898 0.2488196702729086 1.0 0.8835096861819387 4 O43676,P07196 2 +Punctate cataract 0.8367019272817491 1.1526758395935015 0.2490434617123658 1.0 0.8835096861819387 3 Q9H6K4 1 +Blurred vision 0.6638935854601519 1.1507681180594826 0.2498276442590696 1.0 0.8835096861819387 5 P00846 1 +Emg abnormality 0.3715971408892722 1.148841358549158 0.2506214018310346 1.0 0.8835096861819387 86 Q5TAQ9,P46976,P11047,P12235,Q9NR77,Q9NQ11,P07602,Q9BUK6,P07196,Q92734,Q13510,Q7LG56,P51114,Q9Y5P6,Q8NI60,P22626,Q06210,P09651,O75340,O15270,O60313,P09493,Q15120,O95140 24 +Polar cataract 0.7485714285714301 1.1475167875577748 0.2511680989765734 1.0 0.8835096861819387 4 P08670,P25054,Q7LGA3 3 +Increased vldl cholesterol concentration 0.803125939284624 1.1468554972487448 0.2514413480047741 1.0 0.8835096861819387 2 Q8IWV7 1 +Polyhydramnios 0.3882516383647407 1.1442433482165415 0.2525227304481039 1.0 0.8835096861819387 53 Q15125,O75844,Q9UBM7,O43909,Q14739,Q70HW3,P04062 7 +Gliosis 0.3973239946991349 1.144099034224696 0.2525825681671192 1.0 0.8835096861819387 44 Q6PJG6,Q7KZN9,P42858,O75306,Q92734,Q16134,P00846,P35637,P04062 9 +Gray matter heterotopia 0.4299835260551209 1.1425897682092148 0.2532089556712602 1.0 0.8835096861819387 30 Q6ZXV5,Q9Y5P6,P61978,O43505,Q9UBM7,Q86XL3,P31749,Q9UJX6,Q06787 9 +Abnormal cardiac exercise stress test 0.8016230838593321 1.1407791371563687 0.2539618445951874 1.0 0.8835096861819387 2 P0DP25 1 +Generalized myoclonic seizure 0.4095724259049519 1.1372299482036567 0.255442170460272 1.0 0.8835096861819387 39 Q9Y619,Q01105,P07602,O60566,Q9UJX6,P00846,P04062 7 +Abnormal pleura morphology 0.4430631062166742 1.1367991935231003 0.2556222405790591 1.0 0.8835096861819387 24 P14174,Q8NCH0,Q9NZ08,Q14739,O15460 5 +Neoplasm of the gallbladder 0.7455639097744378 1.135935392910502 0.2559836044175307 1.0 0.8835096861819387 4 P07602,Q13043,O43681 3 +Biliary tract neoplasm 0.7455639097744378 1.135935392910502 0.2559836044175307 1.0 0.8835096861819387 4 P07602,Q13043,O43681 3 +Abnormality of the ankles 0.3901805706410316 1.1356809610898446 0.2560901114957945 1.0 0.8835096861819387 47 O75844,P07602,O95140,Q96AY3,Q9UJX6,Q7RTS9 6 +Abnormal circulating fatty acid anion concentration 0.511364481090924 1.1354000998870777 0.2562077178547897 1.0 0.8835096861819387 13 Q16836,P23786,O75880,O43772 4 +Cessation of head growth 0.6004001022722807 1.1348843694363984 0.2564237698183271 1.0 0.8835096861819387 7 Q9Y263,Q13144,Q9NR50,P49770 4 +Dilated cardiomyopathy 0.3902715973979362 1.1341446071630887 0.256733894983348 1.0 0.8835096861819387 46 P53701,Q16836,Q8IWV7,P23786,P09493,O75306,P00846,Q7LG56 8 +Abnormal hand bone ossification 0.6000664380734417 1.1333816948800908 0.2570539978089998 1.0 0.8835096861819387 7 Q15125 1 +Increased intramyocellular lipid droplets 0.599764538914739 1.1320220646384471 0.2576251581374205 1.0 0.8835096861819387 7 Q9BUK6 1 +Ependymoma 0.6333613516700984 1.1307479979845856 0.2581611729387412 1.0 0.8835096861819387 6 O75874,P42771 2 +2 3 toe syndactyly 0.4245631604533801 1.1299729900594768 0.2584876058621632 1.0 0.8835096861819387 32 Q15125,P37268,Q9UBM7,P11233,P34897,Q9UJX6,Q9UHX1 7 +Hip pain 0.6587537580190609 1.129561294654623 0.2586611280575752 1.0 0.8835096861819387 5 P22626,O75844 2 +Thoracic kyphoscoliosis 0.6330191668086775 1.129298547512558 0.2587719134366186 1.0 0.8835096861819387 6 O75844 1 +Disproportionate short trunk short stature 0.6585406366566122 1.1286822022995484 0.2590319198339097 1.0 0.8835550320488524 5 Q7RTS9 1 +Abnormal femoral head morphology 0.4451555860220481 1.1265874322172869 0.259916955227403 1.0 0.8838040770221686 23 O95831,O95613,Q7LGA3,Q99575,O43909,Q7RTS9 6 +Mitochondrial myopathy 0.4175151529663745 1.1255903903773057 0.2603389374874487 1.0 0.8838040770221686 35 O43676,Q9BUK6,P12235,Q96CU9,Q9NPL8,O75306,P00846,P51530,Q7LG56,O60313 10 +Facial hyperostosis 0.7977156597535157 1.1249983055417518 0.2605897523065621 1.0 0.8838040770221686 2 P31749 1 +Fatigable weakness of swallowing muscles 0.4796923617108044 1.1226754423518297 0.2615753614642235 1.0 0.8838040770221686 16 Q92804,P35637 2 +Abnormal csf protein level 0.4931550283026071 1.1217149796486412 0.2619836453628366 1.0 0.8838040770221686 14 P07602,Q9NR77 2 +Abnormal cranial nerve morphology 0.37490769727454 1.1184489181958668 0.2633753116328896 1.0 0.8838040770221686 64 Q9Y5P6,P11047,P12235,Q06210,P22626,Q02978,P31749,P34897,P42356,P07196,Q96TA2,Q92734,Q9UHX1,P09651,Q13510,P51530,Q7LG56 17 +Palmar hyperhidrosis 0.7959122332431512 1.1177237903013382 0.2636849788261306 1.0 0.8838040770221686 2 P07858 1 +Palmoplantar hyperhidrosis 0.7959122332431512 1.1177237903013382 0.2636849788261306 1.0 0.8838040770221686 2 P07858 1 +Heparan sulfate excretion in urine 0.7407518796992497 1.1174205421196386 0.263814555972254 1.0 0.8838040770221686 4 Q96AX1,P54802,P08236 3 +Infectious encephalitis 0.5366201484030966 1.1136802253066846 0.2654163956666733 1.0 0.8838040770221686 11 Q14739,Q9NZ08 2 +Delayed cranial suture closure 0.4278688521044315 1.1135579112545226 0.2654688911360399 1.0 0.8838040770221686 29 Q8NCH0,Q32P28,O75844 3 +Vasculitis 0.5365557098323108 1.113348397450456 0.265558828125862 1.0 0.8838040770221686 11 P01889,P49327,O15460,Q9NZ08 4 +Myalgia 0.3909250877787639 1.1124584914844178 0.2659410676420624 1.0 0.8843471645170606 45 Q9BUK6,P12235,P23786,P21964,P51530,O15460,Q9NZ08,P49327,Q14739,Q06787,Q7LG56,O60313 12 +Abnormal circulating fatty acid concentration 0.4628540454346883 1.1099383013837771 0.2670256143367782 1.0 0.885086588889709 18 Q16836,P23786,O75880,O43772 4 +Abnormality of the phalanges of the hallux 0.73877002185775 1.1098010582810025 0.2670847631851463 1.0 0.885086588889709 4 Q6DKJ4 1 +Decreased light and dark adapted electroretinogram amplitude 0.8246477647160466 1.108271521600573 0.2677445706475607 1.0 0.8866420490291912 3 P50897 1 +Tremor by anatomical site 0.4270109859907533 1.1070745841929428 0.2682616830573847 1.0 0.8870765327952627 29 Q99720,Q9NR77,Q15120,O95140,P35637 5 +Sparse and thin eyebrow 0.5211066820999587 1.1066452291825255 0.2684473442243396 1.0 0.8870765327952627 12 P48449,Q15125 2 +Abnormal morphology of the musculature of the neck 0.4838072411486843 1.1056702895991088 0.2688692540741746 1.0 0.8878406006874873 15 Q99720,P35637 2 +Pectus carinatum 0.411654584200034 1.097131593238544 0.2725838712437756 1.0 0.8922805829776828 36 Q7RTS9,Q96AY3 2 +Short nail 0.6505149896397534 1.09559501722101 0.2732560432527635 1.0 0.8922805829776828 5 O75844 1 +Abdominal distention 0.4407043335946472 1.0955324783623424 0.2732834247304203 1.0 0.8922805829776828 23 P07602,Q7RTS9,Q7LG56,P04062 4 +Anomalous trichromacy 0.820877453823692 1.09441747633738 0.2737719225740251 1.0 0.8922805829776828 3 Q9H6K4 1 +Tritanomaly 0.820877453823692 1.09441747633738 0.2737719225740251 1.0 0.8922805829776828 3 Q9H6K4 1 +Lower limb muscle weakness 0.3887203215679889 1.0922915111017677 0.2747049903734873 1.0 0.8922805829776828 45 Q9Y5P6,Q9NR77,P31749,P07196,Q92734,P00846,Q15120,O95140,O43909 9 +Areflexia 0.3713636214492929 1.091815751221174 0.2749140942942512 1.0 0.8922805829776828 92 Q5TAQ9,P11047,P12235,Q15067,Q9NR77,P61978,O43505,P07196,Q92734,P41440,O95721,Q13510,Q7LG56,P51114,Q9Y5P6,Q15041,Q06210,Q9H6K4,O75340,O60313,O95831,Q15120,O95140 23 +Limited hip movement 0.4814227430000134 1.091444796658033 0.275077210017054 1.0 0.8922805829776828 15 Q96AY3,Q9UJX6,O75844 3 +Abnormal patella morphology 0.4248618559119301 1.0908234570783424 0.2753505727399743 1.0 0.8922805829776828 29 Q96AY3,Q9Y619 2 +Unsteady gait 0.3833144747394382 1.0907805392287782 0.2753694615929976 1.0 0.8922805829776828 52 P42858,O95831,Q9H6K4,Q9NR77,O75503,Q5JRX3 6 +Thin bony cortex 0.7889990982867277 1.089893848477693 0.2757599066776142 1.0 0.8922805829776828 2 P31749 1 +Anasarca 0.7889990982867263 1.089893848477688 0.2757599066776164 1.0 0.8922805829776828 2 Q8IWV7 1 +Profound global developmental delay 0.4811584496324769 1.0898677016737754 0.2757714258816335 1.0 0.8922805829776828 15 P37268 1 +Opisthotonus 0.4363406075075304 1.0891619680368143 0.2760824670398945 1.0 0.8923239199389437 24 P04062,Q99720,P07602,O43909,P35637 5 +Bilateral ptosis 0.4804213720717582 1.085469033756557 0.27771397153399 1.0 0.8941852337274951 15 O75306,O60313,Q7LG56,P11047 4 +Triangular mouth 0.5892890537626813 1.0848433761655931 0.2779910303727231 1.0 0.8941852337274951 7 Q6DKJ4,P11047 2 +Spastic hyperactive bladder 0.6478565484313903 1.0846437730473146 0.278079459846047 1.0 0.8941852337274951 5 P04062 1 +Gastrostomy tube feeding in infancy 0.4187626382214039 1.0846284646265565 0.2780862426728359 1.0 0.8941852337274951 32 Q99720,P30153,P35637,P37268 4 +Disproportionate tall stature 0.4167618118361048 1.0845224252199808 0.2781332295091823 1.0 0.8941852337274951 33 O75648,P42858,Q96PZ0,Q7LGA3,Q8NCH0,P31749,Q9NWM8 7 +Furrowed tongue 0.6472884838068431 1.0823043158771364 0.2791173288832711 1.0 0.8941852337274951 5 P31749 1 +Recurrent fever 0.4729859486813511 1.0817283191458087 0.2793732657961227 1.0 0.8941852337274951 16 P28070,P61978,Q9NR77 3 +High frequency sensorineural hearing impairment 0.646956085677802 1.0809355117413255 0.2797258006941132 1.0 0.8941852337274951 5 Q9NWM8,O75844 2 +Supraventricular arrhythmia 0.4477388926029854 1.080037563116093 0.2801254533983874 1.0 0.8941852337274951 20 P12235,Q99996,Q7LG56,P00846,Q8NFF5,P41227,P50402 7 +Microretrognathia 0.4795086625683568 1.0800215147919772 0.280132599601429 1.0 0.8941852337274951 15 Q8NCH0,Q15125 2 +Truncal titubation 0.816844285155788 1.0796179193382205 0.2803123584750762 1.0 0.8941852337274951 3 Q6PJG6 1 +Hypolipoproteinemia 0.554841142436235 1.077691812204543 0.281171313642194 1.0 0.8947155599844469 8 P37268 1 +Limitation of joint mobility 0.3818308138484592 1.0772033201709377 0.2813894423264731 1.0 0.8947155599844469 108 O75844,P37268,P11047,P23786,O75874,Q9H6K4,O14979,P31749,O95140,Q96AY3,P48735,O43909,Q7RTS9,O15460 14 +Abnormality of canine 0.785091674180941 1.0742053903269957 0.2827306370141165 1.0 0.894926000294368 2 O60341 1 +Posterior polar cataract 0.7850916741809362 1.0742053903269757 0.2827306370141254 1.0 0.894926000294368 2 P08670 1 +Abnormality of glycolipid metabolism 0.5864150685234599 1.071901530533695 0.2837642626990968 1.0 0.8966615682828187 7 P07602,P06280,P17900,O43681 4 +Increased serum pyruvate 0.4084444485680533 1.0707666455692442 0.2842743678399704 1.0 0.8966615682828187 36 O43676,O95831,Q96CU9,O75306,Q9BWD1,Q70HW3,Q5JRX3 7 +Abnormality of lysosomal metabolism 0.6439640909622499 1.0686183664654465 0.2852416691409587 1.0 0.8966615682828187 5 P07602 1 +Abnormality of the fontanelles or cranial sutures 0.3816804145952318 1.0675019982752298 0.2857452117761236 1.0 0.8971205030543707 109 O75844,Q8NCH0,P30153,Q96AY3,Q9Y487,Q9UJX6,Q16134,Q32P28,P61978,Q9Y619,Q8IWV7,P98175,Q02224,P21964,O43909,Q08J23,P31749,O75718,Q15125,P20674,O95831,P28482 22 +Abnormality of the ribs 0.3658866764567449 1.0662614445454417 0.2863054731801298 1.0 0.8971618764494602 67 Q32P28,O75844,Q9Y619,Q6DKJ4,O95831,Q9UBM7,Q9UHX1,Q14739,Q7RTS9 9 +Abnormal placental size 0.7269309905088336 1.0643674629065607 0.2871622674267913 1.0 0.8973339041202284 4 O75844 1 +Abnormality of the sense of smell 0.4550790022362236 1.060059599350487 0.2891174860995875 1.0 0.9011064551577392 18 Q9NQ11,P31749,O95140,P04062 4 +Hydrocephalus 0.3580752183944137 1.0599693080100436 0.2891585625463015 1.0 0.9011064551577392 79 O96028,Q9Y5P6,Q15125,P53701,O43505,Q15392,P23786,Q9UBM7,P21964,P31749,O15360,P30153,O60566,O95140,P04062 15 +Abnormality of prothrombin 0.4823277407082238 1.0585511734427913 0.2898042335750885 1.0 0.9011064551577392 14 Q9UJS0,Q5XKP0,Q16836,P38435,P49257 5 +Orchitis 0.8105832832230776 1.056688171025095 0.2906539253341325 1.0 0.9011064551577392 3 P49327,Q9NZ08 2 +Neuroinflammation 0.8105832832230776 1.056688171025095 0.2906539253341325 1.0 0.9011064551577392 3 P49327,Q9NZ08 2 +Pleuritis 0.8105832832230776 1.056688171025095 0.2906539253341325 1.0 0.9011064551577392 3 P49327,Q9NZ08 2 +Muscle hypertrophy of the lower extremities 0.5501576131245026 1.0552069030412263 0.2913307077341192 1.0 0.9011064551577392 8 Q9NR77 1 +Flat forehead 0.6406547420699202 1.0550032924890411 0.2914238189245699 1.0 0.9011064551577392 5 Q8NCH0 1 +Abnormal muscle glycogen content 0.640279691571727 1.0534608923335085 0.292129808894686 1.0 0.9025589848796668 5 Q9BUK6,O75648 2 +Abnormal intraocular pressure 0.6400069613957425 1.0523393661735427 0.2926438766063408 1.0 0.9029488995885506 5 Q8NCH0 1 +Soft tissue sarcoma 0.4103045450615054 1.049581744918206 0.2939104537251875 1.0 0.9041868910682967 34 Q969G3,P25054,Q15392,O43683,P31749,Q13126,O60566,P42771,P49327,Q15645 10 +Blue sclerae 0.4340952319739707 1.0493520938833008 0.294016098169545 1.0 0.9041868910682967 23 Q8NCH0,Q6DKJ4,Q96AY3 3 +Somatic sensory dysfunction 0.3833458448648376 1.047739410927082 0.2947586844482059 1.0 0.9049404506369706 114 Q5TAQ9,Q9NSE4,Q8IV08,Q9NR77,Q8NCH0,P07602,Q9NQ11,P00846,Q9BUK6,Q9Y619,P41440,Q7LG56,Q9H6K4,Q9NZ08,O15270,Q8N2K0,O95831,Q15120,O95140,O15460 20 +Calcific stippling 0.7224148250387424 1.047078572719042 0.2950633409421246 1.0 0.9050164133244613 4 Q15125 1 +Abnormal proportion of cd4 positive t cells 0.5483052686976487 1.0463144181214483 0.2954158907793593 1.0 0.9050532782712126 8 O43909 1 +Relative macrocephaly 0.4050512006513376 1.0428587806247356 0.2970137025748345 1.0 0.90622267312479 36 O75648,O75844,P42858,Q96PZ0,Q6DKJ4,Q15392,Q7LGA3,Q9UJX6 8 +Abnormality of corneal stroma 0.521829077955643 1.0374597062962858 0.2995216649963383 1.0 0.9062755260718948 11 P10619,O43505,P04062 3 +Constriction of peripheral visual field 0.4350143449993419 1.0337122514052983 0.3012707039080624 1.0 0.9062755260718948 22 P00846,Q9H061,O60313 3 +Abnormal proportion of cd8 positive t cells 0.6098668854573243 1.031313801447774 0.3023936882875093 1.0 0.9062755260718948 6 O43909 1 +Underdeveloped supraorbital ridges 0.5248035008283735 1.0307119281653965 0.3026759294279171 1.0 0.9062755260718948 10 Q6NUK1,P50542,Q08J23,P98175,Q6PGP7,P40855 6 +Osteopenia 0.3563788430005001 1.029696067161649 0.303152702349919 1.0 0.9062755260718948 71 Q32P28,O75844,P07602,Q13126,Q96AY3,Q9Y487,Q9NWM8,Q14108,P04062 9 +Distal sensory loss of all modalities 0.7175939849624079 1.0286527969615016 0.303642858555023 1.0 0.9062755260718948 4 P48643,O15269,O15270 3 +Torsade de pointes 0.8018641010222504 1.024855204372062 0.3054315138896879 1.0 0.9062755260718948 3 P0DP25,P41227 2 +Cachexia 0.4366529978438734 1.0245904405395672 0.3055564769837957 1.0 0.9062755260718948 21 Q99720,Q01844,Q02224,P07602,P31749,P35637,Q7LG56,P04062 8 +Facial myokymia 0.772167117523277 1.0225509240439592 0.3065202234243944 1.0 0.9062755260718948 2 Q9NQ11 1 +Aplastic clavicle 0.7157776709279086 1.0217190772354152 0.3069138792421007 1.0 0.9062755260718948 4 Q9Y2B2,Q9Y619 2 +Temporal optic disc pallor 0.771866546438214 1.0213543456369598 0.307086587147179 1.0 0.9062755260718948 2 O60313 1 +Morning glory anomaly 0.771866546438214 1.0213543456369598 0.307086587147179 1.0 0.9062755260718948 2 O60313 1 +Gowers sign 0.469172036934272 1.018282090833921 0.3085439168923765 1.0 0.9062755260718948 15 P06753,Q9Y5P6,Q9BUK6,Q06210,Q5T8D3,P51530,P07196,O75340,Q13510 9 +Kinetic tremor 0.4019436911845898 1.0172685137479909 0.3090257107725265 1.0 0.9062755260718948 36 P07602,Q8N2K0,Q14108,P41440 4 +Ankyloglossia 0.5741628892559243 1.0167592851924403 0.3092679551294877 1.0 0.9062755260718948 7 Q6DKJ4,O75844 2 +Red green dyschromatopsia 0.7995775706528072 1.0165280128264331 0.3093780147894962 1.0 0.9062755260718948 3 Q9H6K4 1 +Macroorchidism 0.6298939551029313 1.010805289121634 0.3121096311555966 1.0 0.9062755260718948 5 P31749,P38159 2 +Pneumothorax 0.5727112122051317 1.0102307680045548 0.3123847414694598 1.0 0.9062755260718948 7 Q8NCH0 1 +Abnormal hair whorl 0.4283331442177634 1.0090340333898005 0.312958312525927 1.0 0.9062755260718948 23 O75648,P42858,Q96PZ0,Q8IWV7,P30153 5 +Mitral stenosis 0.7970140734734761 1.0072030249495458 0.3138372197276107 1.0 0.9074394305770932 3 O75844 1 +Aortic valve calcification 0.7970140734734761 1.0072030249495458 0.3138372197276107 1.0 0.9074394305770932 3 O75844 1 +Wide cranial sutures 0.5400188685254081 1.0065434238121038 0.3141542341019423 1.0 0.9074394305770932 8 P98175,O75844 2 +Abnormality of the distal phalanges of the toes 0.603712517697295 1.005317958944166 0.3147437701717317 1.0 0.9074394305770932 6 Q7LGA3,O75844 2 +Hamartoma of the eye 0.5196498687988288 1.004553094946307 0.315112092695782 1.0 0.9074394305770932 10 Q02978 1 +Pituitary adenoma 0.4878558933181702 1.004060457907827 0.3153494734166715 1.0 0.9074394305770932 13 P48735 1 +Generalized edema 0.7101092593158338 1.0001119153816316 0.3172563504016537 1.0 0.9074394305770932 4 Q8IWV7,Q13724 2 +Ambiguous genitalia 0.4301278826802484 1.0000337886998167 0.3172941563868159 1.0 0.9074394305770932 22 P53701,Q9UBM7,Q15392,O43683,O60566,Q15645 6 +Neoplasm of the breast 0.4128600411662533 0.9998610773731093 0.3173777429501889 1.0 0.9074394305770932 29 P31749,O75874,P48735 3 +Bone pain 0.4236758446638706 0.9991811109743672 0.3177069644651058 1.0 0.9074394305770932 24 P07602,Q14108,O75874,P48735 4 +Upper limb asymmetry 0.7096506232985451 0.9983658626222984 0.3181019808329441 1.0 0.9074394305770932 4 P31749,Q15555 2 +Abnormality of vitamin b12 metabolism 0.514068860460777 0.9974502749216206 0.3185459985856762 1.0 0.9074394305770932 11 P41440 1 +Gonadal neoplasm 0.4150875603276545 0.99628990739054 0.3191093061242802 1.0 0.9074394305770932 27 P31749,Q01844,O75874,P48735 4 +Hemoglobinuria 0.7088872763040299 0.995460516390216 0.3195123383910698 1.0 0.9074394305770932 4 Q9H0P0,Q969N2 2 +Prolonged partial thromboplastin time 0.6013173068862481 0.995209327903917 0.3196344659962793 1.0 0.9074394305770932 6 P49257 1 +Abnormality of the scrotum 0.373872395854528 0.995166942104534 0.3196550769428432 1.0 0.9074394305770932 51 O75648,Q9Y619,P42858,Q96PZ0,Q15555,Q9UBM7,P31749,O60566 8 +Prominent ear helix 0.7081194279759678 0.9925390034950076 0.3209346628534544 1.0 0.9074394305770932 4 O75844 1 +Abnormality of the posterior pituitary 0.5370606389334863 0.9923514413740387 0.321026117665232 1.0 0.9074394305770932 8 P31749,P42356 2 +Abnormality of the musculature of the lower limbs 0.4116673455118077 0.9908054013004812 0.3217806113533061 1.0 0.9074394305770932 29 Q9NR77,Q9NQ11,O14979,P07196,P00846 5 +Shuffling gait 0.5125316307471828 0.9895253151557496 0.3224061903295525 1.0 0.9076018279672864 11 Q6Y7W6,O75844,P04062 3 +Hyporeflexia 0.3875145007745956 0.9871459136787184 0.3235711121459057 1.0 0.9098667574381094 129 Q5TAQ9,P11047,Q9NSE4,P12235,Q9NR77,Q15067,P07602,P00846,Q9BUK6,O43505,P41440,O43909,Q7LG56,P04062,Q99720,O14979,Q9NYY8,Q8N2K0,O95831,Q15120,O95140,P35637 22 +Chorioretinal dysplasia 0.5993670651830789 0.98698263751428 0.32365115032286 1.0 0.9098667574381094 6 P53701 1 +Neoplasm of the pituitary gland 0.4503766780130007 0.984641468186122 0.3248002128964893 1.0 0.90990962168836 17 O75874,P48735 2 +Genu valgum 0.3996563254522068 0.9805183617154548 0.3268303104650758 1.0 0.9122098290201625 35 Q7RTS9,Q9NR77 2 +Thoracolumbar kyphosis 0.565779289444914 0.9790769954728064 0.3275419372679891 1.0 0.9122098290201625 7 O43909,Q99575,P04062 3 +Abnormal vascular physiology 0.3708760088927965 0.9756214802992116 0.3292520758585744 1.0 0.9150323065190408 53 Q8IZA0,O75844,P11047,P31749,Q9NWM8,Q9NZ08,P49327,Q14739,O15460,Q14108,P04062 11 +Aortic dissection 0.7031874644435534 0.9737977320191632 0.3301569794317229 1.0 0.9150323065190408 4 O15460 1 +Facial diplegia 0.496141609346094 0.972778900299115 0.3306632015030883 1.0 0.9150323065190408 12 P12235,P34897,Q96TA2,P42356,Q7LG56 5 +Ketotic hypoglycemia 0.7595431319506958 0.9724987755084136 0.3308024737568535 1.0 0.9150323065190408 2 P53985 1 +Abnormal caudate nucleus morphology 0.4820442978402861 0.9715626531346728 0.3312681697284116 1.0 0.9150323065190408 13 Q9NQ11,O75306,P00846 3 +Periventricular heterotopia 0.5131199885948604 0.9714161962170044 0.3313410664818841 1.0 0.9150323065190408 10 Q6ZXV5,Q9UBM7,Q06787,Q9UJX6 4 +Incomitant strabismus 0.4412825437762254 0.9714073668287472 0.3313454615101165 1.0 0.9150323065190408 18 P42858,Q96PZ0,O75648,O60313 4 +Everted upper lip vermilion 0.7020529582057075 0.9694927092012352 0.3322994161293331 1.0 0.9151279578080812 4 P04062 1 +Ankle flexion contracture 0.4670715676954026 0.9694343196531464 0.3323285358548449 1.0 0.9151279578080812 14 Q96AY3 1 +Upper limb muscle weakness 0.4102088174456023 0.9693486935572292 0.332371241827972 1.0 0.9151279578080812 28 Q9Y5P6,P46976,P31749,P07196,Q8N0X7,Q92734,P00846,O95140 8 +Abnormal atrioventricular conduction 0.4478774914561964 0.9689715448952207 0.3325593867292253 1.0 0.9151279578080812 17 P50402,O43772,Q99996,P06280,P0DP25,Q7LG56 6 +Soft skin 0.5161743821968909 0.966879590347512 0.3336042306361211 1.0 0.9156051258219742 9 Q13126 1 +Dry skin 0.4052921141033709 0.965612131547323 0.3342383025273847 1.0 0.9156051258219742 31 Q08J23,O95613,P37268,P51648,Q06136,Q6PGP7,P28482 7 +Hypoplasia of the frontal lobes 0.5117265237860498 0.9643469092962592 0.3348720299844827 1.0 0.9156051258219742 10 Q86XL3 1 +Fatty replacement of skeletal muscle 0.5308753174426609 0.9626941838006732 0.3357010163739993 1.0 0.9156051258219742 8 P22626,Q8NFF5,P51114 3 +Postaxial hand polydactyly 0.4937675125637845 0.9600472782352336 0.337031420872953 1.0 0.9156051258219742 12 Q14739,Q9UBM7 2 +Neoplasm of the respiratory system 0.4393270359476345 0.958834362334734 0.3376421954031503 1.0 0.9156051258219742 18 P30154,P31749,Q01844,Q9UJX6 4 +Abnormal lumbar spine morphology 0.5106286992690664 0.9587781437696224 0.3376705219941365 1.0 0.9156051258219742 10 Q99575,P08236,Q96AX1,O43909,P04062 5 +Difficulty climbing stairs 0.4587046602252326 0.9557184976536008 0.3392144745172973 1.0 0.9156051258219742 15 Q9Y5P6,P12235,Q06210,Q92734,O75340,O95140,Q7LG56 7 +Lipoma 0.591944899805665 0.955710857414974 0.3392183355790514 1.0 0.9156051258219742 6 P31749 1 +Entropion 0.5138307546991207 0.9551751261507452 0.3394891423796387 1.0 0.9156051258219742 9 O75844 1 +Muscle fiber atrophy 0.4236082086435925 0.9550656941941924 0.33954447618903 1.0 0.9156051258219742 22 Q99720,P61978,P11047,Q06210,P22626,P23786,P50402,P35637 8 +Inverted nipples 0.6162391414464099 0.9549251286344796 0.3396155610598259 1.0 0.9156051258219742 5 Q15067 1 +J shaped sella turcica 0.6974436090225583 0.9520265526693172 0.3410835157960465 1.0 0.9163988075411228 4 Q96AX1,O60568,P08236 3 +Thick hair 0.5596547906096561 0.9515868875858744 0.3413065341099992 1.0 0.9163988075411228 7 Q9Y487 1 +Abnormal visual fixation 0.5284881227355331 0.9512556280087382 0.3414746258212942 1.0 0.9163988075411228 8 O94992,Q13510,P04062 3 +Mental deterioration 0.3674130207091278 0.951236130206769 0.3414845212808952 1.0 0.9163988075411228 103 P50897,Q9NPL8,Q9NQ11,P07602,O15118,Q9Y487,P00846,Q06787,Q14108,P17900,P42858,P21964,O75503,Q13510,Q7LG56,P04062,P22626,P09651,O95470,Q9NQZ5,O60313,Q5XKP0,P04080,O75306,O95140,P35637 26 +Abnormal neuron morphology 0.4029673478826369 0.9475394330833956 0.343363972374707 1.0 0.919041619043737 31 Q15165,Q99720,Q92804,P22626,Q92734,Q13510,P35637 7 +Broad hallux phalanx 0.780371572763173 0.9469707894931988 0.3436536638219816 1.0 0.919041619043737 3 Q6DKJ4 1 +Atrophy degeneration involving the caudate nucleus 0.5896909923110386 0.9462274255611878 0.3440326006266407 1.0 0.9191588548045282 6 P00846 1 +Abnormality of lipoprotein cholesterol concentration 0.4369602224421569 0.943616502306798 0.3453656562310532 1.0 0.9206738029991958 18 Q8N511,Q9UJS0,P37268,Q8IWV7,Q10471,Q15800,Q5SW96,P48643,P50402 9 +Subcutaneous hemorrhage 0.3777090877228405 0.9434130690826574 0.3454696609617822 1.0 0.9206738029991958 43 Q86YV9,P38435,P28482,Q8NCH0,O15360,Q13126,Q9NWM8,P49257,P49327,Q14108,P04062 11 +Retinal dysplasia 0.5112231383432528 0.9421565011664084 0.346112520640883 1.0 0.921318836130154 9 P53701,O43505 2 +Impaired tandem gait 0.4293426909056587 0.9406881436960493 0.346864696634402 1.0 0.921318836130154 19 P42858,Q96PZ0,Q06787,O75648 4 +Prelingual sensorineural hearing impairment 0.7511271415689612 0.9393832109862646 0.347534029743284 1.0 0.921318836130154 2 Q9NSE4 1 +Childhood onset sensorineural hearing impairment 0.7511271415689612 0.9393832109862646 0.347534029743284 1.0 0.921318836130154 2 Q9NSE4 1 +Tachycardia 0.4034304789917558 0.9391159443673776 0.3476712188747166 1.0 0.921318836130154 30 P46976,O43772,P23786,P09493,P42892,Q8NFF5,P0DP25,P41227 8 +Mandibular prognathia 0.3836009534673423 0.9337958573495364 0.3504092068500084 1.0 0.92246284307949 40 P48651,Q9BUK6,Q6NUK1,P11047,Q9NSE4,Q06210,P25054,Q9Y2B2,P67870,Q9UJX6,Q9UHX1,Q06787,O60828,Q7RTS9 14 +Abnormal corpus striatum morphology 0.4257488258555791 0.9329307660999072 0.3508557160924099 1.0 0.92246284307949 20 Q9NQ11,P00846,O95831,O75306 4 +Abnormal placenta morphology 0.508964303145541 0.9308833750127264 0.3519138951625542 1.0 0.92246284307949 9 O75844 1 +Sporadic 0.4056577444629908 0.9261745882391852 0.3543552564166581 1.0 0.92246284307949 27 Q9BWD1,P04062 2 +Nephrotic syndrome 0.4031569041133279 0.9261297215258026 0.3543785697608819 1.0 0.92246284307949 29 P11047,Q0IIM8,Q8NCH0,O95470,Q14108 5 +Joint contracture of the 5th finger 0.7735730386383315 0.9225355731999452 0.3562492838155773 1.0 0.92246284307949 3 Q9Y2B2 1 +Proximal symphalangism 0.7724739774594651 0.9185955080628648 0.3583071823780026 1.0 0.92246284307949 3 O60828 1 +Large placenta 0.7722418807922682 0.9177638292470928 0.3587425226755285 1.0 0.92246284307949 3 O75844 1 +Anterior uveitis 0.7721833248216106 0.9175540245756032 0.3588523969393793 1.0 0.92246284307949 3 P14174 1 +Poor wound healing 0.5828501884038639 0.917486904752208 0.358887551915513 1.0 0.92246284307949 6 P04062 1 +Macular degeneration 0.4723596268014731 0.9174287014096388 0.3589180385088015 1.0 0.92246284307949 13 P50897,Q13510,P51648,P04062 4 +Brittle hair 0.4521944670747912 0.916814233386252 0.3592399928193361 1.0 0.92246284307949 15 O60828,Q6PGP7,Q9Y487,O75844 4 +Hypoproteinemia 0.6879413003125617 0.916153678900073 0.3595862967619792 1.0 0.92246284307949 4 Q8IWV7,P11047 2 +Abnormality of exocrine pancreas physiology 0.4253660672506303 0.9144484560921944 0.3604812501763237 1.0 0.92246284307949 19 P14174,Q8IWV7,P09601 3 +Type 2 muscle fiber atrophy 0.6873871557401632 0.9140676551963902 0.3606812969896018 1.0 0.92246284307949 4 P11047 1 +Corpus callosum atrophy 0.4513356405308198 0.9116835847549348 0.3619353076652749 1.0 0.92246284307949 15 O75503 1 +Abnormal duodenum morphology 0.4386154003588231 0.910901423613138 0.3623473155191363 1.0 0.92246284307949 17 P78536,P98175,Q8NCH0,O15360,O60566,Q15645 6 +Papilledema 0.4112378761937339 0.9106329733326536 0.3624887909295 1.0 0.92246284307949 24 O75648,P42858,Q96PZ0,P31749,P04062 5 +Abnormal echocardiogram 0.605198073712607 0.9099577641652088 0.3628447843808091 1.0 0.92246284307949 5 Q7LG56 1 +Abnormal circulating carbohydrate concentration 0.37572643921019 0.9041572472492588 0.3659120263503639 1.0 0.92246284307949 42 O43676,O95831,Q96CU9,O75306,Q9BWD1,Q70HW3,Q5JRX3 7 +Short palpebral fissure 0.3988400625278768 0.9038116085007564 0.366095305220544 1.0 0.92246284307949 30 O75844,Q9Y619,Q15555,P98175,P55795,Q03164,Q86W42,O15360,Q9UHX1 9 +Cranial nerve compression 0.4996352858450558 0.9030604171377424 0.3664938304306175 1.0 0.92246284307949 10 P22626,Q02978 2 +Speech apraxia 0.4024921014257974 0.9026202222356235 0.3667274901608206 1.0 0.9224652588810268 27 P42858,Q96PZ0,O75648,Q9Y619 4 +Unilateral renal agenesis 0.4211115307794962 0.9018840180272488 0.3671184820188409 1.0 0.922950136220153 20 Q86XL3,Q7LGA3,Q9UBM7,P30153,Q9UHX1 5 +Rhabdomyolysis 0.4551860415106118 0.900020621048731 0.3681092768815417 1.0 0.9233156976191152 14 O43772 1 +Hip contracture 0.4824228429905598 0.8992523843125091 0.3685182435510701 1.0 0.9233156976191152 12 P06753,Q96AY3,Q7LGA3,Q9UJX6 4 +Focal white matter lesions 0.5173701204138879 0.8980577371188334 0.3691547689760597 1.0 0.9233156976191152 8 Q7LG56 1 +Asymmetric septal hypertrophy 0.7403065825067647 0.8971412128138554 0.3696435696653846 1.0 0.9233156976191152 2 P54802 1 +Ventricular hypertrophy 0.3746779167652232 0.8948417529491325 0.3708716871407678 1.0 0.9233280125806246 42 P46976,O75844,P11047,Q6NUK1,P78536,P12235,O43772,P23786,P06280,O75880,Q7LG56 11 +Myositis 0.4980084755275763 0.8948247316535279 0.3708807874702919 1.0 0.9233280125806246 10 P22626,P28070,Q9NZ08 3 +Atrophic scars 0.516672359364979 0.8947240532010077 0.370934617411504 1.0 0.9233280125806246 8 Q8NCH0 1 +Abnormality of the gingiva 0.362990621370552 0.8903492287633288 0.3732783951550071 1.0 0.9258627402460716 51 Q15392,O43909,Q14739,P49257,Q14108,P04062 6 +Abnormal lower motor neuron morphology 0.4970736438127169 0.8900935376748644 0.3734156626611247 1.0 0.9258627402460716 10 Q99720,P35637 2 +Abnormality of the intrinsic pathway 0.4931420061758353 0.8896644890107949 0.3736460672084125 1.0 0.9258627402460716 11 P49257,Q9Y487 2 +Abnormal cell morphology 0.5455868848762724 0.8886127547334421 0.3742112338715055 1.0 0.9261318554689036 7 Q7LG56 1 +Abnormality of alkaline phosphatase level 0.4137045152490223 0.8867309516032559 0.375223770186083 1.0 0.9263212481370108 22 Q9UJS0,Q8N511,P22626,Q9Y2B2,Q96A33,Q96AY3,P09651,Q14739 8 +Multiple cafe au lait spots 0.4470457075407699 0.8860640114399359 0.3755830346291311 1.0 0.9267168040451692 15 O95613,O15360,P31749,O60566,Q15645 5 +Micropenis 0.34772510116416 0.8838182136465612 0.3767943526473551 1.0 0.9282298973153892 68 Q9Y5P6,P53701,Q9Y619,P48449,Q8IWV7,O43505,Q9UBM7,P42892,O95470 9 +Convex nasal ridge 0.4073862706549691 0.8832024476512766 0.3771268993819143 1.0 0.928477929563736 24 O96028,Q9H9E3,Q6NUK1,O75844,O95613,Q8IWV7,P25054,Q02224,P51530 9 +Abnormal st segment 0.7621306241926564 0.8816636478667503 0.3779587248247145 1.0 0.928477929563736 3 P46976 1 +St segment elevation 0.7621306241926564 0.8816636478667503 0.3779587248247145 1.0 0.928477929563736 3 P46976 1 +Infantile axial hypotonia 0.4790909615830767 0.8814181675363556 0.3780915280182224 1.0 0.928477929563736 12 O43909,P07602 2 +Hereditary nonpolyposis colorectal carcinoma 0.4948417545744057 0.8788022466306998 0.37950850794283 1.0 0.9298902103628868 10 P31749,O60566,O43683 3 +Abnormality of the musculature of the upper limbs 0.3398084279262894 0.878448788891387 0.3797002174369595 1.0 0.9298902103628868 76 P62857,Q9Y5P6,P11047,P12235,Q9NR77,O14979,P07602,P07196,Q9Y487,Q15120,O95140,Q7LG56,O60313 13 +Saccadic smooth pursuit 0.6773046049190563 0.8762386206276508 0.3809003250885339 1.0 0.9306302405400316 4 Q06787,O14773 2 +Synostosis of metacarpals metatarsals 0.6772719199159741 0.8761163948223687 0.3809667608396263 1.0 0.9306302405400316 4 O60828 1 +Corneal opacity 0.3574867637439046 0.875049479233602 0.3815469841421772 1.0 0.9314818873994324 58 O96028,P53701,O75844,O43505,Q15056,Q9Y2B2,P51648,O43683,Q9UBM7,Q06136,O60566,P10619,P06280,Q15645,Q13510,O15111,P04062 17 +Hypoplastic ilia 0.4939196813481354 0.8741392939039915 0.3820424008321694 1.0 0.9314818873994324 10 O95613,Q7RTS9 2 +3 methylglutaconic aciduria 0.4975766937472203 0.8741303269373198 0.3820472835415618 1.0 0.9314818873994324 9 Q9H6K4 1 +Slow saccadic eye movements 0.4632596273535516 0.8666271606902806 0.3861463268109011 1.0 0.9356320980482724 13 Q9NQ11,Q8IV08,P04062 3 +Increased circulating lactate dehydrogenase concentration 0.4435222984882105 0.8650357094058398 0.3870191894678609 1.0 0.9360838161882392 15 P23786,P41440 2 +Decreased activity of mitochondrial complex iv 0.4372697175054322 0.8632764393169886 0.3879854949651888 1.0 0.9361910714417022 16 Q70HW3,Q9Y2R0 2 +Multiple lipomas 0.5097822701318283 0.8618445148517014 0.3887730851902129 1.0 0.9361910714417022 8 P31749,O95140 2 +Abnormal protein o linked glycosylation 0.6721103003098061 0.8568496034155715 0.3915280078592826 1.0 0.9361910714417022 4 Q8N511,Q10471 2 +Prominent superficial blood vessels 0.4613474388710044 0.8559645863941803 0.3920173681263035 1.0 0.9361910714417022 13 P48651,Q6NUK1,O75844,Q13043,Q9Y487 5 +Abnormal epidermal morphology 0.4116674383392526 0.8548494303504965 0.3926345092245173 1.0 0.9361910714417022 21 P78536,O75844,P16615,P31749,Q06136,P01889,Q14574 7 +Emg neuropathic changes 0.3960435312622619 0.8546335826624276 0.3927540299912522 1.0 0.9361910714417022 27 P22626,Q9NR77,P07602,O95140,O60313 5 +Pleural effusion 0.4608405139764386 0.8531387928652199 0.3935823409876455 1.0 0.9361910714417022 13 P14174,Q14739,Q9NZ08 3 +Ureteral stenosis 0.5671200998851612 0.851693482736667 0.3943842388025591 1.0 0.9361910714417022 6 Q9UBM7,Q9UJX6 2 +Vitritis 0.753368402176626 0.8506031929009494 0.394989815202365 1.0 0.9361910714417022 3 P53701 1 +Loss of ability to walk 0.4409007574702702 0.8493999565315398 0.3956587773460316 1.0 0.9361910714417022 15 P00846,Q7LG56 2 +Abnormality of skeletal muscle fiber size 0.413110280701853 0.8483433120591193 0.3962468030625778 1.0 0.9361910714417022 20 Q9BUK6,O95831,P22626,P09651,O60313 5 +Sparse eyelashes 0.4127215224563483 0.8457434787140821 0.3976958624619677 1.0 0.9361910714417022 20 P48449,Q15125 2 +Vaginal neoplasm 0.5882271601981084 0.8413292583766935 0.4001635039592655 1.0 0.9361910714417022 5 Q15645,O60566 2 +Tetraparesis 0.3747064247017624 0.8394465400731498 0.4012187767807442 1.0 0.9361910714417022 39 P00846,Q7RTS9,P35637 3 +Aplasia hypoplasia involving bones of the thorax 0.3744474413677619 0.8372244199914533 0.4024664334528176 1.0 0.9361910714417022 39 O75844,Q9Y619,O95613,P98175,O60566,Q9UHX1,Q14739,Q7RTS9 8 +Ascending tubular aorta aneurysm 0.5869242868591047 0.8360894034540332 0.4031046092167805 1.0 0.9361910714417022 5 Q06787,O75844 2 +Titubation 0.4704424991045323 0.8351939010193866 0.4036085431084024 1.0 0.9361910714417022 12 Q6PJG6,Q99720,Q5JRX3,P35637 4 +Hyperinsulinemic hypoglycemia 0.5626433605299026 0.8330589495512161 0.4048114837066796 1.0 0.9361910714417022 6 Q16836,P53985 2 +Congenital contracture 0.3579172614781512 0.8325726425998617 0.4050857933575402 1.0 0.9361910714417022 46 O75844,Q15392,Q8NCH0,Q96AY3,P04062 5 +Smooth muscle antibody positivity 0.7234746017432916 0.8322852883456272 0.4052479325931113 1.0 0.9361910714417022 2 P49327 1 +Ventricular preexcitation 0.5035714926185546 0.8322767571463371 0.4052527469031715 1.0 0.9361910714417022 8 P00846 1 +Hypopigmentation of the skin 0.3549783768028763 0.8300189022892722 0.4065280965942208 1.0 0.9361910714417022 55 Q86YV9,P53701,Q8IZA0,Q15125,O95613,P21964,O15360,P07602,Q9Y2Q5,P31749,Q9UJX6,Q6PGP7,P49327 13 +Paraparesis 0.3861622455040748 0.8283719344448047 0.407459895753764 1.0 0.9361910714417022 32 Q9Y619,P35637,Q9H6K4,Q9NQ11,Q6DKK2,P42356,P04062 7 +Abnormal shoulder morphology 0.3842856306579202 0.8261882813904219 0.4086972947384002 1.0 0.9361910714417022 33 Q96PZ0,Q7RTS9 2 +Renal agenesis 0.3544851275948289 0.8251219189463165 0.4093023767534121 1.0 0.9361910714417022 55 P62857,Q9UBM7,Q15392,Q86XL3,O75306,O15360,O43924,P30153,Q9UJX6,Q9UHX1 10 +Irregular capital femoral epiphysis 0.7213706041478787 0.8242591773230069 0.4097923087700792 1.0 0.9361910714417022 2 P50542 1 +Abnormal t cell subset distribution 0.4683616045770112 0.8240897011464122 0.4098885915282317 1.0 0.9361910714417022 12 O43909,P17812 2 +Leiomyosarcoma 0.4838374749242596 0.8232383768397166 0.4103724490844207 1.0 0.9361910714417022 10 P31749,O60566,O43683 3 +Progressive peripheral neuropathy 0.7453397474443607 0.822342877877494 0.4108817797742643 1.0 0.9361910714417022 3 P07602,O43681 2 +Vegetative state 0.7453397474443607 0.822342877877494 0.4108817797742643 1.0 0.9361910714417022 3 P07602,O43681 2 +Dysphagia 0.3785474334653551 0.8212797629912614 0.4114869320723544 1.0 0.9361910714417022 138 P11047,P12235,Q01105,Q9NR77,Q15067,P07602,Q9NQ11,O15118,P48735,P00846,Q14739,Q8NFF5,Q06787,Q14108,Q8IZA0,P42858,Q92734,Q9UHX1,Q7LG56,P04062,Q99720,Q06210,O75874,P42356,O60313,O75306,P35637 27 +Abnormal renal cortex morphology 0.3538376384771255 0.8186929688199731 0.4129616092057386 1.0 0.9361910714417022 55 P11047,Q02978,Q0IIM8,Q6PGP7,Q9NZ08,P00846,P49327,O95470,Q14108 9 +Hyperactive patellar reflex 0.4828078202786289 0.8180501443690025 0.4133285550635279 1.0 0.9361910714417022 10 Q15041 1 +Dyscalculia 0.4544621047871163 0.8176189212165643 0.4135748199410269 1.0 0.9361910714417022 13 P22626,Q06787,Q9UJX6,P35637 4 +Tetraplegia tetraparesis 0.35528561401595 0.8159259124234957 0.4145425107200249 1.0 0.9361910714417022 51 P00846,Q7RTS9,O95831,P35637 4 +Right ventricular hypertrophy 0.580974165995079 0.8122185361175626 0.4166662452130913 1.0 0.9361910714417022 5 P11047 1 +Abnormality of the septum pellucidum 0.3675197569499283 0.8120504475110695 0.4167626849852244 1.0 0.9361910714417022 41 O96028,P53701,O43505,Q15392,Q9UJX6,Q9NZ01,P28482 7 +Eyelid myoclonus 0.4847935770607957 0.8106478355007855 0.4175679378964982 1.0 0.9361910714417022 9 P00374,Q13510,Q01105 3 +Calvarial hyperostosis 0.5805412679846559 0.8104857567904948 0.417661047884841 1.0 0.9361910714417022 5 P31749,P22626 2 +Branchial anomaly 0.4984529212421864 0.8079677003297915 0.4191091762865833 1.0 0.9372585613786416 8 P28482,Q9UHX1 2 +Hypoplastic female external genitalia 0.4276278330226164 0.8044396067667492 0.4211431349166998 1.0 0.9377868065876184 16 Q9Y619 1 +Cupped ear 0.4215975078269273 0.8043817586567523 0.4211765327543351 1.0 0.9377868065876184 17 Q15392 1 +Abnormal pyramidal sign 0.3752929489247519 0.8025947295528937 0.4222090156125162 1.0 0.9377868065876184 135 Q9NR77,Q15067,P07602,Q9NQ11,P34897,P00846,Q9Y619,P42858,P07196,P41440,Q6DKK2,Q7LG56,Q99720,Q9Y5P6,Q8NI60,Q9H6K4,Q9NZ08,P49327,O60313,Q8N2K0,O95831,O75306,O95140,P35637 24 +Lower limb asymmetry 0.5550659772032137 0.8016258246525306 0.4227694345743411 1.0 0.9377868065876184 6 P31749,Q15555 2 +Abnormality of the elbow 0.3448281280078182 0.800437810723468 0.423457181455166 1.0 0.9377868065876184 64 Q9Y619,P37268,P23786,Q96AY3,O43909,Q7RTS9 6 +Headache 0.3342929438855316 0.7978405266218296 0.424963039948617 1.0 0.9377868065876184 72 P12235,Q0IIM8,P23786,Q02978,P31749,O15460,Q9NZ08,P00846,P49327,Q7LG56,O60313,P04062 12 +Thin skin 0.394355554289888 0.7904720086341549 0.4292521631151909 1.0 0.942001011864798 24 Q13126,Q9Y619 2 +Impaired mastication 0.4944598755007745 0.7890460531742923 0.4300850903774997 1.0 0.9423417321400652 8 P06753,O15460,P11047 3 +Deep plantar creases 0.5516109014607019 0.7873424384934025 0.431081432876081 1.0 0.9431932102777412 6 Q9Y487 1 +Excessive salivation 0.3790483629435946 0.7844390928220111 0.432782507387762 1.0 0.9432944342234866 33 O43909,P55795,P42356,Q9NR77 4 +Abnormality of the autonomic nervous system 0.3399275034113939 0.7844137162012359 0.4327973926939357 1.0 0.9432944342234866 67 Q15067,O15360,P07602,Q9UJX6,Q99996,Q04446,Q06787,P21964,P41440,P0DP25,P04062,Q9Y2B2,P42892,P06280,O15270,Q6PJG6,Q9UBM7,Q6Y7W6,P48643,P41227 20 +Acute lymphoblastic leukemia 0.411824983522289 0.7822554037345308 0.4340644900102854 1.0 0.943618308779844 18 Q08J23,Q9Y2B2,O43683,O60566,Q9UJX6,Q15645 6 +Cardiac conduction abnormality 0.3752114336741813 0.7808837916551906 0.4348708458440109 1.0 0.943618308779844 35 P00846,O43772,Q7LG56,P23786 4 +Abnormal arterial physiology 0.3839999947334691 0.7804294400154023 0.4351381447962366 1.0 0.943618308779844 29 O75844,Q9NWM8,Q9NZ08,Q14739,O15460 5 +Abnormal larynx morphology 0.3823873472827037 0.7772432091738307 0.4370152937926408 1.0 0.943618308779844 30 P21964,P07602,Q9UHX1,O43909,Q14739,Q13510 6 +Poor coordination 0.471110859981753 0.7767512338956496 0.4373055531241179 1.0 0.943618308779844 11 Q9Y619 1 +Scapular winging 0.3892612294997889 0.7749364419036852 0.4383772171646423 1.0 0.943618308779844 25 P06753,Q9Y5P6,Q8TD16,Q8WXH0,P11047,Q06210,P07196,Q9Y487,O75340,P50402,O60313 11 +Abnormal anterior chamber morphology 0.648877857691086 0.7711008219021129 0.4406471734846611 1.0 0.9441570362377276 4 Q8NCH0 1 +Cutaneous finger syndactyly 0.6484555102443941 0.7695583993739015 0.4415618900770774 1.0 0.94430731319964 4 O15111,Q9Y619 2 +Fasting hypoglycemia 0.7274911052819675 0.7602847607880808 0.4470843890112959 1.0 0.946523466595078 3 O43772 1 +Protuberant abdomen 0.5444654322843369 0.7579109706102306 0.448504282231724 1.0 0.946523466595078 6 Q7RTS9 1 +Abnormal retinal artery morphology 0.3895083006376728 0.756042200891962 0.4496238941449579 1.0 0.946523466595078 24 P17900,P21964,P07602,P00846,P10619 5 +Cough 0.3795585476302461 0.7555038965084466 0.4499466952502278 1.0 0.946523466595078 30 O15270,P04062,P41440,Q9NR77 4 +Incisor macrodontia 0.4007454696334952 0.7523452478037129 0.4518434637502801 1.0 0.946523466595078 19 P42858,Q96PZ0,O75648 3 +Abnormality of upper limb joint 0.366240983112874 0.7511803509844166 0.4525441237618173 1.0 0.946523466595078 127 O75844,P37268,P11047,Q15392,Q9NR77,Q96AY3,Q9UJX6,Q7RTS9,Q8IZA0,Q9Y619,Q7LGA3,P07196,O43909,Q13510,O96028,Q6DKJ4,O95613,P23786,Q9H6K4,P31749,P42892,Q15125,O95831,P28482 24 +Restlessness 0.3602480317932549 0.7481389163568378 0.4543763706407624 1.0 0.946523466595078 41 Q6PJG6,Q15165,Q92804,P42858,P48449,P42892,P09651,P35637,P04062 9 +Frontotemporal dementia 0.4540724919849494 0.7480904699063441 0.4544055899546375 1.0 0.946523466595078 12 P22626,P35637 2 +Abnormal sclera morphology 0.3785718546084858 0.7479244844782776 0.4545057081113541 1.0 0.946523466595078 30 Q8NCH0,P31749,Q6DKJ4,Q96AY3 4 +Multiple mitochondrial dna deletions 0.7238580838656534 0.7477954481686766 0.4545835480941584 1.0 0.946523466595078 3 Q7LG56 1 +Nocturia 0.7238580838656534 0.7477954481686766 0.4545835480941584 1.0 0.946523466595078 3 Q7LG56 1 +Irritability 0.3335797086751743 0.7472501401241471 0.4549125831613558 1.0 0.946523466595078 82 P50897,P37268,O95831,O43772,Q15067,Q9NZ08,P00846 7 +Juvenile onset 0.357915668607229 0.745740352998418 0.4558242776762906 1.0 0.946523466595078 42 P06753,P04080,Q06210,Q9NR77,Q9NQ11,O15118,P07196,P41440,P48643,P06280,Q13510,P50402 12 +Decreased calvarial ossification 0.6416779549419717 0.7448961711770902 0.4563344899580015 1.0 0.946523466595078 4 O75844 1 +Prominent forehead 0.3316443028503486 0.7441268163327336 0.4567997573390636 1.0 0.946523466595078 80 O75648,Q9NSE4,Q96PZ0,P42858,Q15392,P23786,P11233,Q7LGA3,Q6PGP7,Q9UJX6,Q9UHX1,Q14739,Q06787 13 +Difficulty running 0.4282788162933476 0.7435430483180496 0.4571529688669185 1.0 0.946523466595078 14 P06753,Q9Y5P6,Q06210,P07196,O75340,O95140 6 +Perimembranous ventricular septal defect 0.5127700061508258 0.7431999808168084 0.4573606149828979 1.0 0.946523466595078 7 Q9UHX1,Q86W42 2 +Progressive external ophthalmoplegia 0.4637706415539693 0.7393633574084724 0.4596863863936893 1.0 0.9471572397844048 11 P51530,Q7LG56,O60313 3 +Thin eyebrow 0.4222565689721363 0.7385826574032892 0.4601604583149279 1.0 0.9471572397844048 15 P48449,Q15125 2 +Thoracic scoliosis 0.4399483312689435 0.737122943167616 0.4610475880159692 1.0 0.9471572397844048 13 P06753,Q9NSE4,O75844,Q9UHX1 4 +Progressive spasticity 0.4162508684418529 0.7352716304955046 0.4621740821789775 1.0 0.9471572397844048 16 Q9NQ11,P07602,O60313 3 +Toe walking 0.383475993321633 0.7331858597154578 0.4634450785085207 1.0 0.9471572397844048 25 O95831,P07602,P35637 3 +Widely patent fontanelles and sutures 0.6383881612361151 0.7329883208046115 0.4635655527404954 1.0 0.9471572397844048 4 O75844 1 +Episodic pain 0.4263165805891521 0.7321982929946448 0.4640475460850515 1.0 0.9476339362157894 14 P23786 1 +Hallucinations 0.3471684491418663 0.7318234017837061 0.4642763635487641 1.0 0.9476855540039656 46 P50897,Q9NQ11,P07602,O75503,Q6DKK2,P35637,O60313,P04062 8 +Motor axonal neuropathy 0.395369770736538 0.7299889772681862 0.4653969223268539 1.0 0.9487250745857408 20 O95831,P22626,O15270 3 +Pulmonary artery dilatation 0.4153036841637158 0.7295297646925581 0.4656776675290017 1.0 0.9488819343610644 16 P42858,Q96PZ0,O75648 3 +Spinal canal stenosis 0.4677215886176165 0.7264369100444238 0.4675709708437483 1.0 0.9500592863845604 9 O43909,P31749 2 +Cns demyelination 0.4147591544602936 0.7262301486647151 0.467697692604385 1.0 0.9500592863845604 16 Q13144,P51648,Q15067,Q9NZJ7,P07602,P40855,P49770 7 +Thin clavicles 0.6360988129489786 0.7247271058858462 0.4686194626969158 1.0 0.9500592863845604 4 O75844 1 +Metaphyseal irregularity 0.4376728307062764 0.7245556997842152 0.4687246446429292 1.0 0.9500592863845604 13 Q7RTS9 1 +Aplasia hypoplasia of the hallux 0.3818941284737356 0.7217852828195136 0.4704264991665279 1.0 0.9500592863845604 25 O75648,P42858,Q96PZ0,Q7LGA3,Q9UHX1 5 +Central apnea 0.5076291112459078 0.7206902048509078 0.4711001402996913 1.0 0.9500592863845604 7 Q9NZJ7,P07602,O76024 3 +Ankle clonus 0.4240800689096783 0.7192832183542526 0.4719664336864686 1.0 0.9500592863845604 14 Q969N2,P42858,Q9NZJ7,P07602,Q8N0X7,O60220 6 +Gait imbalance 0.3815396617746989 0.7192316573254078 0.4719981969106588 1.0 0.9500592863845604 25 O15270,Q7LG56,Q9NR77 3 +Pedal edema 0.4794034868562733 0.7180984819703474 0.4726965661086995 1.0 0.9500592863845604 8 Q14108,P04062 2 +Cone shaped epiphysis 0.4237330003307226 0.717280558123884 0.4732010009847216 1.0 0.9500592863845604 14 O95831,Q7RTS9,Q02224 3 +Status epilepticus 0.3454335142928434 0.7169483875069228 0.4734059437620077 1.0 0.9500592863845604 49 P07602,P42892,P53701,Q15392 4 +Generalized onset motor seizure 0.3440338891363668 0.7129967066504553 0.4758477950579181 1.0 0.9500592863845604 53 Q9Y619,Q01105,P07602,O60566,Q9UJX6,P00846,P04062 7 +Abnormal sternum morphology 0.3566027474471314 0.7122851235013187 0.4762882342422554 1.0 0.9500592863845604 117 P55795,Q8NCH0,P30153,Q96AY3,Q9Y487,Q9UJX6,Q14739,Q7RTS9,Q06787,Q9BUK6,P61978,Q9Y619,P98175,Q7LGA3,Q9UHX1,O43909,Q13510,P04062,O96028,Q08J23,Q6DKJ4,P31749,O75718,O60566,P42356,Q15555,O95831 27 +Abnormality of the musculature of the hand 0.359503984466416 0.7090099740256748 0.4783182873746607 1.0 0.9517307461608636 39 P11047,Q9NR77,P07196,Q15120,O95140 5 +Delayed ability to walk 0.3277749874254464 0.7072767847757032 0.4793944894758752 1.0 0.952679095706617 71 Q6PJG6,Q99720,O75648,P48449,Q96PZ0,Q01105,P11233,P34897,Q9NYY8,P35637 10 +Holoprosencephaly 0.4344879953094757 0.7069954966822701 0.4795692763330503 1.0 0.952679095706617 13 Q15645,Q9Y5P6,Q9UBM7,O60566 4 +Abnormal circulating carboxylic acid concentration 0.3381040335585951 0.7062549659323571 0.4800295937028243 1.0 0.952679095706617 92 Q9Y619,P37268,P23786,P48735,P41440,P00846,Q14739 7 +Distal amyotrophy 0.3348798981563012 0.7053601513016411 0.4805861359345971 1.0 0.952679095706617 65 Q99720,Q5TAQ9,Q9BUK6,Q9NR77,Q15120,O95140,O15270,Q8N2K0,P35637 9 +Bilateral sensorineural hearing impairment 0.3792047138917841 0.7024205164247126 0.4824169542737353 1.0 0.952679095706617 25 P07602,P38159,P35637,Q15067 4 +Ascites 0.3724298046234204 0.7007935161612244 0.4834318850189807 1.0 0.952679095706617 30 P04062,Q15645,Q01844,Q13043,O43683,O15118,O60566,Q14739,Q04446,Q13510,Q14108,P08236 12 +Posterior pituitary dysgenesis 0.7093069350733137 0.6983105808084817 0.4849829836160271 1.0 0.952679095706617 3 P42356 1 +Overlapping toe 0.3858708557000149 0.6952750764677395 0.4868829304665856 1.0 0.952679095706617 22 Q15125,P61978,Q9UBM7,Q9UHX1,P28482 5 +Increased connective tissue 0.5014606346669497 0.6938053128019653 0.4878043103826317 1.0 0.9530914264127291 7 O95831 1 +Abnormal oral mucosa morphology 0.3336493538313364 0.6921547619305369 0.4888401445033952 1.0 0.9531859204905426 65 Q6DKJ4,Q9UBM7,Q15392,Q9NZ08,O43909,Q14739,P49257,Q14108,P04062 9 +Polyphagia 0.5281697339571652 0.6914178161291413 0.4893030110844569 1.0 0.9531859204905426 6 P42858 1 +Absent septum pellucidum 0.3687029048937676 0.6910168026276086 0.4895549818461775 1.0 0.9531859204905426 32 P53701,Q15392,O43505 3 +Exercise intolerance 0.3621474711384128 0.6882198915141674 0.491314319453227 1.0 0.9537122664093876 36 Q9Y5P6,Q9Y2R0,Q9H2D1,Q8NI60,P12235,P23786,P51530,Q7LG56 8 +Diaphragmatic eventration 0.6847009317703641 0.6878300799117703 0.4915597914820435 1.0 0.9537122664093876 2 O60568 1 +Arthropathy 0.5272069426487297 0.6875199249969962 0.4917551491529981 1.0 0.9537122664093876 6 O15270,Q9Y3Z3 2 +Moderately reduced visual acuity 0.705325021809764 0.6849290236016983 0.4933887102094376 1.0 0.9537122664093876 3 O60313 1 +Delayed menarche 0.526543328733376 0.6848354271681855 0.493447777014651 1.0 0.9537122664093876 6 Q9UJS0,O75844 2 +Decreased number of large peripheral myelinated nerve fibers 0.4992053395507059 0.6840121528701805 0.4939674917658756 1.0 0.9543205981999654 7 Q7LG56 1 +Myoglobinuria 0.4523075259588073 0.6813072175767866 0.4956771172861716 1.0 0.955245305498516 11 P23786 1 +Aplasia hypoplasia of the ribs 0.383712708598 0.6805173579321765 0.4961769348333733 1.0 0.9554176214161232 22 Q14739 1 +Broad toe 0.3677854530896331 0.6739830768601759 0.5003220728489448 1.0 0.9583757115346788 31 Q15125,O75648,P42858,Q96PZ0,Q7LGA3,P30153,Q9UHX1 7 +Abnormality of the gastric mucosa 0.3947938672897071 0.6736915165685555 0.5005074564339456 1.0 0.9583757115346788 18 Q15056,Q6PGP7,P49327,Q14739,P04062 5 +Phimosis 0.5457132902489983 0.6732047777173503 0.5008170220814683 1.0 0.9583757115346788 5 Q9UJX6 1 +Chronic pulmonary obstruction 0.4567574862762532 0.6728344243654737 0.5010526345817325 1.0 0.9583757115346788 9 P09601,P21964 2 +Limited extraocular movements 0.469058147153673 0.6697978408814438 0.5029866701556531 1.0 0.9583757115346788 8 O75306 1 +Aplasia hypoplasia of the phalanges of the hand 0.3365302469483822 0.6688954129456626 0.5035621965052086 1.0 0.9583757115346788 59 P48651,Q6NUK1,O75844,Q969G3,Q6DKJ4,O95613,Q03164,P38435,O95630,Q9Y2B2,O60826,Q9UHX1,O43909,P28482,Q14739,P35453,Q7RTS9,O15111 18 +Angina pectoris 0.5444100609003333 0.6681632520737089 0.5040293898380874 1.0 0.9583757115346788 5 P06280,O75844 2 +Abnormal pulmonary interstitial morphology 0.3670224336406625 0.6680732307934023 0.5040868483838841 1.0 0.9583757115346788 31 P14174,Q8IZA0,P09601,P49327,Q13510,Q14108,P04062 7 +Bifid tongue 0.6200131897510236 0.6673137373012219 0.5045717534312568 1.0 0.9583757115346788 4 Q6DKJ4,Q9UBM7 2 +Skin rash 0.3817542965652414 0.6671422096062846 0.5046813007732158 1.0 0.9583757115346788 22 P28070,Q14739,Q06136 3 +Neoplasm of the skeletal system 0.3401062995061035 0.6654276788017675 0.5057769863069987 1.0 0.9583757115346788 48 Q92804,Q13126,O75874,P48735 4 +Femoral hernia 0.678088367898998 0.6640241161625342 0.5066748761286073 1.0 0.9583757115346788 2 P48651 1 +Early onset of sexual maturation 0.3421536934423487 0.6628417218458047 0.5074319294883316 1.0 0.9583757115346788 45 O96028,O75648,P42858,Q96PZ0,Q9UBM7,Q7LGA3,O75874,P48735 8 +Hepatitis 0.3987684575571487 0.6625287123229124 0.5076324399475869 1.0 0.9583757115346788 17 Q9Y619,Q13043,P49327,P11717,P08236 5 +Overlapping fingers 0.4674637478646803 0.6623921637678688 0.5077199244792647 1.0 0.9583757115346788 8 Q15125 1 +Premature graying of hair 0.4545151071380294 0.6619287094721218 0.5080169114278734 1.0 0.9583757115346788 9 P49327,Q13126 2 +Skin dimple 0.3661816587383185 0.6615636171199837 0.5082509310560765 1.0 0.9583757115346788 31 O96028,P53701,Q15125,P61978,Q08J23,Q6DKJ4,Q03164,O43909 8 +Poor gross motor coordination 0.6982683415446925 0.6613957642268359 0.5083585416302507 1.0 0.9583757115346788 3 O75503 1 +Hand tremor 0.4376140496294226 0.661305104999744 0.5084166682754847 1.0 0.9583757115346788 12 Q15120,P07196,O95140 3 +Agenesis of cerebellar vermis 0.6978352375225352 0.6599591993876774 0.5092800125745318 1.0 0.9591061319780518 3 O43924,Q10713 2 +Contractures of the large joints 0.6972339146121426 0.6579661949974378 0.5105598536105793 1.0 0.959131302430607 3 Q9Y263,P50542 2 +Abnormality of the metopic suture 0.4368755132286329 0.6574351703690532 0.5109011434031587 1.0 0.959131302430607 12 P28482,P30153 2 +Proximal amyotrophy 0.4030726544461219 0.6556867625471394 0.5120256878092886 1.0 0.959131302430607 16 Q06210,O14979,P07196,Q92734,P35637 5 +Lymphopenia 0.3684373277744945 0.655662205498024 0.5120414916513494 1.0 0.959131302430607 28 P28070,P17812,Q6PGP7,O43909,O95470 5 +Abnormal ldl cholesterol concentration 0.4028311378249786 0.6542350751685092 0.5129603671906324 1.0 0.959131302430607 16 Q8N511,Q9UJS0,P37268,Q15800,P48643,P50402 6 +Microdontia 0.3626080297729928 0.6536571199140574 0.5133327350896368 1.0 0.959131302430607 33 Q6NUK1,Q9Y619,O95613,Q8IWV7,Q15555,Q7LGA3,Q15056,Q9Y2B2,Q9Y487,P28482 10 +Anosmia 0.5405658471873926 0.6533388617207205 0.5135378441449883 1.0 0.959131302430607 5 O95140 1 +Increased muscle glycogen content 0.6956344729045004 0.6526737585501527 0.5139666233824896 1.0 0.959131302430607 3 Q9BUK6 1 +Fatigue 0.3311212648398544 0.6524041040662188 0.5141405174954103 1.0 0.959131302430607 89 P04062,Q15165,Q92804,Q02978,P12235,Q9NQ11,P07602,Q4J6C6,Q9NZ08,O15460,Q14739,Q70HW3,Q7LG56,O60313,P35637 15 +Abnormal bone structure 0.3837512969630516 0.6505042298126665 0.5153665704096109 1.0 0.960197853770515 181 O75844,Q9NSE4,Q15392,P07602,Q96AY3,P48735,Q9Y487,Q14739,Q7RTS9,Q14108,Q32P28,Q9Y619,Q9NWM8,O43909,Q7LG56,P04062,P22626,O75874,P31749,Q13126,Q9HC07,Q15125,O95831,P38435,Q86XL3,Q9UBM7 26 +Abnormal thyroid morphology 0.348821265969916 0.6478270836694786 0.5170967960099464 1.0 0.960197853770515 41 P12235,O75874,P31749,P42892,P48735,Q7LG56 6 +Abnormal mitochondrial number 0.6938535964221778 0.6467960032484067 0.5177639794218136 1.0 0.960197853770515 3 P51530 1 +Sparse or absent eyelashes 0.3678044241348426 0.6451833228068025 0.5188083923402829 1.0 0.960197853770515 27 P48449,Q15125 2 +Increased vertebral height 0.6726780883679002 0.6447533126067972 0.5190870615657803 1.0 0.960197853770515 2 Q96J02 1 +Bilateral coxa valga 0.6726780883678848 0.6447533126067421 0.5190870615658161 1.0 0.960197853770515 2 Q96A33 1 +Bile duct proliferation 0.693076553763613 0.6442364050544243 0.5194221471157645 1.0 0.960197853770515 3 Q5XKP0 1 +Abnormal lactate dehydrogenase level 0.3840806648836383 0.6435285812006918 0.5198811752814065 1.0 0.960197853770515 19 Q5JRX3,P23786,P41440 3 +Premature loss of primary teeth 0.6925995651672817 0.6426667150779626 0.5204403831629987 1.0 0.960197853770515 3 P04080 1 +Poor motor coordination 0.410520185202787 0.6413967294541184 0.5212649573377259 1.0 0.960197853770515 14 P42858,Q9Y5P6,O95140,O75503 4 +Weakness of facial musculature 0.3330504057917127 0.6402493684147925 0.5220104918005841 1.0 0.960197853770515 60 Q9Y5P6,Q9BUK6,P11047,P12235,Q06210,P31749,P34897,P42356,P07196,Q96TA2,Q9UHX1,Q13510,P51530,Q7LG56,O60313 15 +Acute phase response 0.3654816202214946 0.6401194513914871 0.5220949440747473 1.0 0.960197853770515 29 P28070,O15460,Q02978,P41440 4 +Neoplasm of fatty tissue 0.4439813796003083 0.6394501136141926 0.5225301569082585 1.0 0.960197853770515 11 P31749,O95140 2 +Omphalocele 0.4220895351460305 0.6390125260097567 0.5228147832467398 1.0 0.960197853770515 13 Q6DKJ4,Q14739,O15111 3 +Abnormal venous morphology 0.3651760534019824 0.6378142835486554 0.5235945804738487 1.0 0.960197853770515 29 P48651,Q6NUK1,P47985,P98175,Q13043,P21964,P31749,Q9Y487,P04062 9 +Irregular hyperpigmentation 0.3191027019994864 0.6375973874629919 0.5237357967587837 1.0 0.960197853770515 76 O75648,O75844,Q15555,P42858,Q96PZ0,Q8IWV7,O95613,Q7LGA3,P16615,O43683,O15360,Q06136,P31749,O60566,Q6PGP7,P28482,Q14739,Q15645 18 +Corneal erosion 0.611536521593304 0.637544597240519 0.5237701702703537 1.0 0.960197853770515 4 P51648 1 +Epistaxis 0.3998794382947848 0.6365163679635615 0.5244399160161688 1.0 0.9605791695402368 16 P49257,P38435,O15460,P04062 4 +Malignant neoplasm of the central nervous system 0.3671661344732101 0.6357067988250544 0.524967544198867 1.0 0.9611674737671748 26 O75874,Q9UJX6,P48735 3 +Atrophy degeneration involving the corticospinal tracts 0.3994790523955806 0.6341162935793806 0.5260049300862621 1.0 0.9623100017609576 16 P00846 1 +Dysgenesis of the cerebellar vermis 0.6693718064322226 0.6330721260031612 0.5266865437882569 1.0 0.9626465885681706 2 Q10713 1 +Penetrating foot ulcers 0.6894255194203585 0.6322512999989982 0.5272226805946811 1.0 0.9626465885681706 3 O15270 1 +Trophic changes related to pain 0.6894255194203585 0.6322512999989982 0.5272226805946811 1.0 0.9626465885681706 3 O15270 1 +Emg slow motor conduction 0.6894255194203585 0.6322512999989982 0.5272226805946811 1.0 0.9626465885681706 3 O15270 1 +Abnormal placental membrane morphology 0.6681695220919764 0.6288428357127851 0.5294519532913027 1.0 0.9631973937692824 2 P21281 1 +Photophobia 0.3499798175654169 0.6274692948208418 0.5303516573231741 1.0 0.9631973937692824 39 Q86YV9,Q15555,P48449,P07602,Q9NZ08,P49327,Q96S66 7 +Decreased circulating progesterone 0.5121877821245905 0.6272278526126325 0.5305098882725021 1.0 0.9631973937692824 6 Q9UI10,Q13144,Q14232,Q9NR50,P49770 5 +Abnormal circulating progesterone level 0.5121877821245905 0.6272278526126325 0.5305098882725021 1.0 0.9631973937692824 6 Q9UI10,Q13144,Q14232,Q9NR50,P49770 5 +Abnormality of circulating enzyme level 0.3402043119427078 0.625431078554731 0.5316881699042386 1.0 0.9636201319868176 104 Q16836,P12235,Q8NFF5,P50402,P15291,Q6ZXV5,P53985,Q9BUK6,O75648,O43505,O43772,P07196,Q9NWM8,Q92734,P51530,Q7LG56,Q9Y5P6,Q08J23,P22626,Q06210,P23786,O14979,P09651,Q9HC07,O75340,O95831,P09493,Q15120,Q5JRX3 29 +Abnormal t wave 0.5319742480129663 0.6204740578563587 0.5349457283258097 1.0 0.9661393759057292 5 P0DP25,P46976 2 +Advanced eruption of teeth 0.4401057092447382 0.620071435011038 0.5352107574597322 1.0 0.966243228667124 11 O75844 1 +Abnormal circulating ige level 0.4840380846109012 0.6187233574097485 0.5360986199618147 1.0 0.9666690522993738 7 O43909,P49327 2 +Clonus 0.3594082573502478 0.6182135156676181 0.5364346019006945 1.0 0.9666690522993738 32 Q99720,Q9Y5P6,Q9Y619,P42858,P07602,P35637 6 +Nail dysplasia 0.3616186861961979 0.618137485049573 0.5364847145922642 1.0 0.9666690522993738 30 O96028,P10321,Q6DKJ4,Q9Y619,Q99575,P42892,P16615 7 +Transposition of the great arteries 0.4837879950689568 0.6176559223633876 0.5368021730237471 1.0 0.9668668926880334 7 O75844 1 +Abnormal nephron morphology 0.3265352480414502 0.6158436326875684 0.5379977267874176 1.0 0.9682855141478016 65 P11047,Q02978,Q0IIM8,P23786,O75306,Q9NZ08,P00846,O95470,Q14108 9 +Abnormal synaptic transmission at the neuromuscular junction 0.3577851005724907 0.6154483272069131 0.5382586842699173 1.0 0.9682855141478016 33 Q15165,Q9Y5P6,P11047,Q92804,Q06210,Q92734,P09651,Q7LG56,P35637 9 +Hyperextensible skin 0.4012471585203983 0.615075665636787 0.5385047517163202 1.0 0.9682855141478016 15 Q8NCH0,Q9NWM8,P04062 3 +Skin plaque 0.5089148751589947 0.614228444560509 0.5390643794077399 1.0 0.9685356995359446 6 Q06136 1 +Membranoproliferative glomerulonephritis 0.663059813645929 0.6109806418012401 0.5412123960045554 1.0 0.9695788928004104 2 O95394 1 +Morphological abnormality of the corticospinal tract 0.3845973165140242 0.6092730392395634 0.5423434744639024 1.0 0.9695788928004104 18 P00846 1 +Abnormal urine ph 0.3425432516911887 0.6091954192997447 0.5423949161997652 1.0 0.9695788928004104 42 Q16836,P12235,O43772,P23786,Q16134,P48735,P00846,O75880 8 +Aphthous ulcer 0.4557928546167271 0.6085400545850737 0.5428293486957911 1.0 0.9695788928004104 8 Q9NZ08 1 +Abnormality of the achilles tendon 0.4000943701500404 0.6083598883458183 0.5429488088572305 1.0 0.9695788928004104 15 Q15041,Q08J23,Q92734,O60313,Q8N2K0 5 +Intestinal malrotation 0.3590450887357366 0.6064300473863589 0.5442292207546533 1.0 0.9704830531726027 31 Q8NCH0,Q14739,Q15392 3 +Hemoptysis 0.5068464053254166 0.6060407752074215 0.5444876770848175 1.0 0.9705514648430198 6 P49327,Q9NZ08 2 +Craniosynostosis 0.3381184347003731 0.6056566718185568 0.5447427613809901 1.0 0.9705514648430198 44 P61978,Q9Y619,Q08J23,Q02224,P21964,Q8NCH0,P31749,Q9UJX6,O43909 9 +Hyperlipidemia 0.3577154447381956 0.6049941377816295 0.5451828918247004 1.0 0.9705514648430198 32 P28070,O95470,P23786,O75844 4 +Occipital encephalocele 0.4800990382688054 0.6019481541610989 0.5472086490450456 1.0 0.9720730522524732 7 Q9Y5P6,O43505,Q6ZXV5 3 +Abnormality of subcutaneous fat tissue 0.3888218880350875 0.6013981829281622 0.5475748086478367 1.0 0.9723525206194996 17 Q9Y487,O75844 2 +Joint stiffness 0.3281895771837752 0.5974409130624511 0.5502130451218905 1.0 0.9733432065123848 61 O75844,O75874,P31749,Q96AY3,P48735,O95140 6 +Abnormal brainstem mri signal intensity 0.3668640240965775 0.5962440810293843 0.5510121814049476 1.0 0.9733432065123848 24 Q8N183,O43676,O95831,Q9Y6M9,Q96CU9,Q9NPL8,O75306,Q86Y39 8 +Metatarsus valgus 0.6782104782893663 0.5958817084184659 0.5512542536345297 1.0 0.9733432065123848 3 O43505 1 +Ureteral obstruction 0.4785909924796019 0.595547542123508 0.5514775298066303 1.0 0.9733432065123848 7 Q9UBM7,Q9UJX6 2 +Restless legs 0.6772532755475547 0.5928099713799028 0.5533083337525093 1.0 0.9754652033137764 3 O95140 1 +Dyspnea 0.3420487761392217 0.5890396352448797 0.555834685735551 1.0 0.9765566811354456 111 P53701,O75844,P11047,P12235,P07602,Q16134,P00846,O75648,Q9Y619,Q92734,Q9UHX1,P51530,Q7LG56,Q13510,P04062,P62857,P23786,P09651,P06280,Q15165,Q92804,O95831,O75306,Q86TI2,P35637 25 +Abnormal sputum 0.451480405103857 0.5888163554239575 0.5559844730435746 1.0 0.9765566811354456 8 Q9NZ08 1 +Neoplasm of the eye 0.3917867351657845 0.5881782511898612 0.5564126539327656 1.0 0.9765566811354456 16 Q02978 1 +Broad thumb 0.3583763828431408 0.5866408669358907 0.5574449298817159 1.0 0.9765566811354456 29 O75648,P42858,Q96PZ0,Q6DKJ4,Q7LGA3,Q9UHX1 6 +Abnormality of long bone morphology 0.3794111026610596 0.5841586378755997 0.559113586720507 1.0 0.9765566811354456 184 O75844,P37268,Q9NSE4,Q96PZ0,Q9NR77,O15360,Q96AY3,P48735,Q9Y487,Q14739,Q7RTS9,Q32P28,O75648,Q9Y619,P42858,P98175,Q7LGA3,Q02224,Q9UHX1,O43909,O96028,Q08J23,Q6DKJ4,O95613,P22626,O75874,Q9Y2B2,O75718,Q13126,Q9HC07,Q15125,O95831,P38435,Q9UBM7,P28482 35 +Pustule 0.5223266922934058 0.5840468341088841 0.5591888028650227 1.0 0.9765566811354456 5 P07858,P78536 2 +Mutism 0.3803907081736382 0.5828675819079094 0.5599824454705504 1.0 0.9765566811354456 18 P53701,P42858,P22626,Q13510,P35637 5 +Severe global developmental delay 0.3140403894820965 0.5821909140553874 0.5604380927536514 1.0 0.9765566811354456 73 O75648,P42858,Q96PZ0,Q7LGA3,Q15067,O60566,P00846,Q7RTS9,O43909 9 +Visual field defect 0.3311576471146399 0.5820229594657804 0.5605512160165798 1.0 0.9765566811354456 46 Q9H6K4,O75306,P31749,P00846,O95140,O15460,O60313 7 +Psychotic episodes 0.5953329272195534 0.5816978712249424 0.5607702056797832 1.0 0.9765566811354456 4 Q5JRX3 1 +Airway obstruction 0.374492070662869 0.5815271255464051 0.5608852419287187 1.0 0.9765566811354456 19 P09601,O75844,P21964 3 +Abnormality of the parathyroid gland 0.3691020543595326 0.5811996506750985 0.5611059030800911 1.0 0.9765566811354456 22 P48735 1 +Antinuclear antibody positivity 0.5214780538094093 0.5808683724921201 0.561329169739099 1.0 0.9765566811354456 5 P49327 1 +Anonychia 0.3997876510149052 0.5803872095901123 0.5616535285069879 1.0 0.9765566811354456 14 Q6NUK1,O14936,P25054,P16615,P28482,Q14739 6 +Unexplained fevers 0.4749571994435983 0.5801760141480001 0.5617959269752419 1.0 0.9765566811354456 7 P07602 1 +Abnormality of the uterus 0.3276462399929809 0.5781501012652388 0.5631627840731617 1.0 0.9779670085888292 59 O96028,Q16740,P53701,Q9UBM7,P21964,O15360,P31749,P30153,O60566 9 +Progressive cerebellar ataxia 0.3385004588382341 0.5734183259163478 0.5663614849888687 1.0 0.9780266788500368 42 Q9BUK6,Q9Y619,P42858,Q96CU9,Q9NQ11,O75306,Q9Y487,P41440,P35637 9 +Abnormality of head blood vessel 0.3573739907077241 0.5733760722146399 0.5663900878982053 1.0 0.9780266788500368 28 P48651,P17900,Q15056,P21964,Q5SW96,P07602,P00846,P10619,Q13510 9 +Neoplasm of the endocrine system 0.3401015432587647 0.5715495963415266 0.5676271509496935 1.0 0.9780266788500368 41 P42892,O75874,P48735,Q02978 4 +Oculogyric crisis 0.4299300919591588 0.5695586217201011 0.568977099956018 1.0 0.9780266788500368 11 Q01105,P35270 2 +Hypoventilation 0.3974643790917683 0.567270956541066 0.5705301061591896 1.0 0.9780266788500368 14 Q8N183,P06753,P61978,P11047,O75306,O75380 6 +Spastic paraparesis 0.3669394114942352 0.5666058179225987 0.5709820213517478 1.0 0.9780266788500368 22 Q6DKK2,Q9H6K4,P04062,Q9Y619 4 +Biparietal narrowing 0.4346302905804801 0.5662658170148738 0.5712130940018803 1.0 0.9780266788500368 9 Q9UBM7 1 +Telecanthus 0.3442646078473687 0.5658905663867517 0.5714681748453674 1.0 0.9780266788500368 38 Q15125,O75844,Q08J23,Q86XL3,P21964,Q8NCH0,Q16134,O60828 8 +Fibroadenoma of the breast 0.517104356259843 0.564556976508756 0.5723751357838314 1.0 0.9780266788500368 5 P31749 1 +Diffuse mesangial sclerosis 0.3717722185872822 0.5640462872136436 0.5727226313293658 1.0 0.9780266788500368 19 O95470,P11047 2 +Abnormal uvula morphology 0.3313934644586678 0.5636855365627516 0.5729681623416703 1.0 0.9780266788500368 45 P61978,Q9Y619,Q6DKJ4,O43505,Q15392,O15360,P34897,Q6PGP7 8 +Ectopic calcification 0.3276634960486384 0.5628161424294356 0.5735600870484607 1.0 0.9780266788500368 56 Q15125,O75844,P38435,P23786,Q14739,O60313,P04062 7 +Abnormal incisor morphology 0.3700014291829082 0.5627496135840941 0.5736053949743436 1.0 0.9780266788500368 20 P42858,Q96PZ0,O75648 3 +Hip dysplasia 0.3279937963578158 0.5621759778488394 0.5739961266320699 1.0 0.9780266788500368 55 O96028,Q15125,O75648,P61978,P42858,Q96PZ0,O95613,Q7LGA3,Q02224,P30153,Q9UHX1 11 +Supranuclear gaze palsy 0.3660667769366621 0.5607263714863027 0.5749840866221696 1.0 0.9780266788500368 22 P04062,Q99720,Q9NQ11,P07602,P35637 5 +Abnormal morphology of the conjunctival vasculature 0.4952358020426577 0.5605120132136449 0.575130247876376 1.0 0.9780266788500368 6 P10619 1 +Inflammation of the large intestine 0.3962126671475695 0.5602190460817609 0.5753300373751906 1.0 0.9780266788500368 14 P08183,Q13546,Q6PGP7,P01889,P49327 5 +Abnormal thrombosis 0.3562115691993802 0.5600699399458828 0.5754317331843046 1.0 0.9780266788500368 27 O75874,P31749,P48735,Q9NZ08,O15460 5 +Pain 0.3799047996409486 0.558041145191434 0.5768162883102423 1.0 0.9780266788500368 192 P14174,P28070,O75844,P12235,Q9NR77,P07602,P48735,P00846,Q14739,Q70HW3,Q14108,Q9BUK6,Q15800,P51530,Q7LG56,P04062,P22626,P23786,O75874,Q9H6K4,P31749,P42892,Q9NZ08,O15270,O60313,Q15165,Q92804,Q02978,Q01844,O95140,O15460,P35637 32 +Abnormal cardiac test 0.370785356632054 0.5577165860299043 0.5770379299994723 1.0 0.9780266788500368 19 Q9Y5P6,P46976,Q16836,P12235,P0DP25,Q7LG56 6 +Supraventricular tachycardia 0.4944220095640453 0.5573498218821519 0.5772884417929147 1.0 0.9780266788500368 6 Q8NFF5,P41227 2 +Abnormal shape of the palpebral fissure 0.4175804338969652 0.5572922786370231 0.577327750341837 1.0 0.9780266788500368 12 P28482,P55795,Q9UHX1 3 +Malrotation of small bowel 0.5878883600657021 0.5565513631860823 0.5778339920259106 1.0 0.9780266788500368 4 Q8NCH0 1 +Abnormality of the maxilla 0.3486414429120049 0.5533696498553006 0.5800103168824178 1.0 0.9780266788500368 34 Q14739,Q9Y619 2 +External ophthalmoplegia 0.3755413998485634 0.5525733701417485 0.5805555810599476 1.0 0.9780266788500368 18 P51530,Q7LG56,O60313 3 +Aplasia hypoplasia involving bones of the lower limbs 0.3294439304835045 0.5515677770069509 0.5812445185141453 1.0 0.9780266788500368 98 P15260,Q96PZ0,Q8N0X7,Q96AY3,Q06787,Q7RTS9,O75648,Q9Y619,P42858,Q03164,Q7LGA3,Q02224,Q9UHX1,Q13510,O15111,O96028,Q08J23,Q9Y2B2,O00116,O95831,Q9Y4W2,Q9UBM7,Q99575,Q96A33 24 +Mesoaxial polydactyly 0.6639192170230679 0.5505840322388069 0.5819188573944929 1.0 0.9780266788500368 3 O43924 1 +Visual fixation instability 0.5859001938277986 0.5498941877754671 0.5823919509927997 1.0 0.9780266788500368 4 O94992,Q13510 2 +Abnormality of vitamin b metabolism 0.3941289675457998 0.5485036778029359 0.5833461046290356 1.0 0.9780266788500368 14 P41440 1 +Arm dystonia 0.5853004176357423 0.5478908737191361 0.5837668356786012 1.0 0.9780266788500368 4 P35637 1 +Multiple joint contractures 0.3640011452312861 0.5468311319506076 0.584494752746292 1.0 0.9780266788500368 22 P51530,O75844,P41440 3 +Gastroparesis 0.4668123069030304 0.5460017361140412 0.585064743817151 1.0 0.978119011566483 7 P12235,Q7LG56 2 +Nonimmune hydrops fetalis 0.3526394186803122 0.5436800720238811 0.5866616480377558 1.0 0.9794858973150916 29 P10619,Q14739,P04062 3 +Exercise induced muscle cramps 0.4907898121345715 0.5432851217007663 0.586933506608061 1.0 0.9794858973150916 6 P23786 1 +Blindness 0.3192237378143842 0.541920754066388 0.5878730988042473 1.0 0.980308525434966 86 P50897,Q9Y5P6,P53701,O43676,P11047,Q15555,O43505,Q96CU9,Q9H6K4,Q9NPL8,O75306,P07602,P31749,Q9NZ08,P00846,P49327 16 +Young adult onset 0.4134039740743408 0.5359017736897957 0.5920264385698817 1.0 0.9837527116278976 12 Q9NQ11,P38435,P07602 3 +Synostosis involving digits 0.4885575445841172 0.5346820679443225 0.5928697234181972 1.0 0.9839743811688584 6 O95613,O60828 2 +Sparse body hair 0.425285667453447 0.5337998507845683 0.5934800170234307 1.0 0.9839743811688584 10 P48449,Q06787,P04080 3 +Abnormality of temperature regulation 0.336417632560727 0.5312472972738377 0.5952474213874925 1.0 0.9839743811688584 110 P14174,P28070,Q0IIM8,O43772,P23786,Q9NR77,Q9NQ11,P07602,P35270,Q9NZ08,P00846,P49327,Q14739,Q9HC07,O15460 15 +Myopathy 0.3321305557586478 0.5310924302198268 0.5953547295766981 1.0 0.9839743811688584 104 P46976,P11047,P12235,Q8NCH0,P00846,Q8NFF5,P50402,P15291,O43676,Q9BUK6,O75648,P07196,Q9NWM8,P51530,Q7LG56,P51114,Q9Y5P6,P22626,Q06210,P23786,O14979,P31749,Q13126,P09651,O75340,O60313,P09493,O75306,Q86Y39 29 +Brachydactyly 0.3107864477936085 0.5309064499193765 0.5954836079607233 1.0 0.9839743811688584 77 Q08J23,P48449,O95831,Q9NSE4,Q9UBM7,Q6DKJ4,O95613,P31749,Q06136,O43924,Q9UHX1,O43909,Q14739,Q7RTS9 14 +Ichthyosis 0.3444628330287068 0.5308233531428155 0.5955411954754817 1.0 0.9839743811688584 35 Q15125,P48449,O95470,Q15800,P51648,O95721,P04062 7 +Autoamputation 0.5070603761286792 0.5275639156247565 0.5978020435957483 1.0 0.9859604374714148 5 P48643,O15270 2 +Retinal detachment 0.3760814919270722 0.5239931155681056 0.6002833282093045 1.0 0.9876039491669688 17 Q8NCH0,P31749,Q9Y5P6,O43505 4 +Cerebral white matter atrophy 0.3623142011701675 0.5234399837609803 0.6006681057874577 1.0 0.9878193965807968 21 O75503 1 +Myopathic facies 0.4855638695364306 0.5231949403755703 0.6008386020439898 1.0 0.9878193965807968 6 Q9Y5P6,Q9BUK6 2 +Tall stature 0.3225151961013702 0.5204856846901232 0.6027251028944991 1.0 0.9881939302804325 58 O96028,O75648,P61978,P42858,Q96PZ0,Q7LGA3,Q8NCH0,P31749,Q9UJX6,Q9NWM8,P51530 11 +Posteriorly rotated ears 0.3395859459196225 0.5202759534859644 0.6028712534479221 1.0 0.9881939302804325 116 P37268,Q15392,Q8NCH0,Q9Y619,P98175,O43505,Q7LGA3,Q4J6C6,Q9UHX1,P04062,P62857,O96028,Q08J23,Q6DKJ4,P23786,P11233,P42892,O60566,Q9HC07,Q15555,Q9UBM7,O43924,P28482 23 +Fasting hyperinsulinemia 0.576770436587184 0.5196570431156153 0.6033026322178616 1.0 0.9881939302804325 4 Q16836 1 +Melanocytic nevus 0.4101836613963427 0.5194895755435119 0.6034193804982879 1.0 0.9881939302804325 12 Q96AY3 1 +Abnormal tissue metabolite concentration 0.3889356053227045 0.5194415954027362 0.6034528312276706 1.0 0.9881939302804325 14 P17900,P50542,Q5T8D3,Q9NZJ7,P07602,P06280,O43681 7 +Bulbar palsy 0.4100690995627546 0.5189070750908826 0.6038255437387952 1.0 0.9881939302804325 12 P06753,Q9Y263,P19367,O43681,Q13148,P35637 6 +Flat face 0.3532157354470174 0.5170972456657973 0.6050882762455427 1.0 0.9886451913919372 25 Q15125,P50542,Q96C86,Q15555,Q03164,Q9NX62,Q9Y487,O60568,P08236 9 +Follicular hyperkeratosis 0.4597687221692004 0.5167865457893264 0.6053051730318919 1.0 0.9886451913919372 7 Q9NWM8 1 +Genital neoplasm 0.3335538232421539 0.5145380724364507 0.6068758491266832 1.0 0.9901402324222236 41 Q01844,O75874,P31749,Q9UJX6,P48735 5 +Aspiration 0.4186105495415458 0.5140916078290689 0.607187944521673 1.0 0.9901402324222236 11 P42356 1 +Woolly hair 0.5026995626620707 0.5117171344704932 0.6088489924684113 1.0 0.9909600743138016 5 Q6PGP7 1 +Abnormal circulating sulfur amino acid concentration 0.4341164936960815 0.5105328063448574 0.6096782370524763 1.0 0.9909600743138016 8 P41440 1 +Vascular skin abnormality 0.3456542763627065 0.5082596931579116 0.6112712331134382 1.0 0.9909600743138016 127 P53701,O75844,P51648,Q8NCH0,O15360,Q06136,Q9Y487,P00846,Q14739,Q14108,Q8IZA0,Q86YV9,P21964,Q9NWM8,P04062,Q08J23,Q9Y2B2,P31749,P07858,Q13126,P49257,P10619,P49327,P06280,Q15125,P38435,Q9UBM7,O75306,P28482 29 +Cavernous hemangioma 0.5016906999404778 0.5080704492360427 0.6114039382370813 1.0 0.9909600743138016 5 P31749 1 +Parkinsonism 0.3468913876072837 0.5065505994714243 0.61247017785495 1.0 0.9909600743138016 30 Q99720,P35637,Q9NQ11,P07602,Q06787,P04062 6 +Stage 5 chronic kidney disease 0.3458533157951206 0.5052859388183087 0.6133580174202939 1.0 0.9909600743138016 31 O95470,P23786,P11047 3 +Lumbar hyperlordosis 0.361077057066974 0.5048797019911673 0.6136433315041623 1.0 0.9909600743138016 20 O43909,Q9Y5P6,Q7RTS9,O95140 4 +Bifid uvula 0.3369567813893685 0.5045948449209894 0.6138434313224639 1.0 0.9909600743138016 38 O43505,Q15392,Q6PGP7,Q9Y619 4 +Heart block 0.3485070511431832 0.5040074796334509 0.6142561209187001 1.0 0.9909600743138016 27 P46976,P23786,O43772,Q7LG56,P06280,P50402 6 +Pes cavus 0.3325633213026677 0.5026412411364155 0.6152165282553608 1.0 0.9909600743138016 108 Q5TAQ9,Q96PZ0,Q9NR77,Q9NQ11,Q14739,Q9BUK6,O75648,P42858,Q7LGA3,P07196,P04062,Q99720,Q8NI60,Q9H6K4,O60313,Q8N2K0,O95831,Q9Y4W2,Q15120,O95140 20 +Bone spicule pigmentation of the retina 0.4209119944039018 0.5016151558706209 0.6159382562852489 1.0 0.9909600743138016 9 Q96S66 1 +Cognitive impairment 0.3697348672244832 0.5011365964799709 0.6162749925669724 1.0 0.9909600743138016 176 P50897,Q9Y2R0,P12235,Q9NPL8,Q9NQ11,P07602,O15118,Q9Y487,P00846,Q06787,Q14108,P17900,Q9Y619,P42858,Q02224,P21964,P07196,O75503,Q6DKK2,Q13510,Q7LG56,P04062,Q99720,Q9Y5P6,O95613,P22626,Q9H6K4,P31749,P35270,Q9NZ08,P09651,P49327,P06280,O95470,O60313,Q9NQZ5,Q5XKP0,P04080,O95831,O75306,Q6PGP7,O95140,P35637 43 +High myopia 0.4193634223049711 0.4943998017654639 0.6210238539715647 1.0 0.9930235345767644 9 Q9Y487 1 +Abnormal lower limb bone morphology 0.371351976843028 0.4934338062832433 0.6217061003632449 1.0 0.9930235345767644 182 O75844,Q96PZ0,Q15392,P07602,O15360,Q96AY3,Q9Y487,Q14739,Q7RTS9,Q06787,Q32P28,O75648,Q9Y619,P42858,P98175,O43505,Q7LGA3,Q02224,P21964,Q9UHX1,O43909,Q13510,P04062,O96028,Q08J23,Q6DKJ4,O95613,Q9Y2B2,P31749,O75718,Q15125,O95831,Q9Y4W2,Q9UBM7,O43924,P28482 36 +Decreased circulating igg level 0.4044427085777146 0.4904199873477677 0.6238367359835171 1.0 0.9954454162298472 12 O43909,P17812 2 +Cortical cataract 0.643893943458995 0.4893112927440651 0.6246213273306362 1.0 0.9954454162298472 3 Q9H6K4 1 +Oligohydramnios 0.342304035776381 0.4854688866622829 0.6273437778003674 1.0 0.9954454162298472 32 Q9Y5P6,Q6NUK1,Q7LGA3,P23786,Q9Y2B2,O15360,O60566,Q9UHX1,Q15058,P51114,Q9NSD9 11 +Functional motor deficit 0.3609369353993982 0.4828408646564799 0.629208732810232 1.0 0.9954454162298472 159 P53701,Q9Y2R0,P11047,P12235,Q9NR77,Q15067,P07602,Q9NQ11,P00846,Q7RTS9,Q9BUK6,P42858,P07196,Q9NWM8,P51530,Q7LG56,P04062,Q99720,Q9Y5P6,Q9H2D1,Q15041,Q8NI60,P23786,P31749,Q15120,O95140,P35637 27 +Asymmetric growth 0.4120854040008861 0.4825217902134048 0.6294353228633929 1.0 0.99546564648504 11 P31749,Q15125,Q15555 3 +Abnormality of body mass index 0.6407698655876641 0.480003664318458 0.6312247874659234 1.0 0.9957388647001736 3 P42858 1 +Aplasia hypoplasia of the earlobes 0.4110213306320253 0.4774045004236716 0.6330741101318371 1.0 0.9971559731981846 11 O95613,P98175,P10586,Q02224,P21964 5 +Abnormality of humoral immunity 0.3164716993738334 0.4763106264654018 0.633853095922682 1.0 0.9973707382953726 61 Q9UJS0,P14174,P28070,P78536,P02786,Q13546,P15260,P17812,Q9Y2Q5,Q6PGP7,P09601,O43909,P49327,Q14108,P04062 15 +Oromandibular dystonia 0.4922531494492117 0.4743270669507485 0.6352666928704447 1.0 0.9989198655875686 5 P35637 1 +Decreased pulmonary function 0.561309762536087 0.469788336387537 0.6385062482918187 1.0 1.0 4 P31749,P08236 2 +Optic neuropathy 0.3425722888144109 0.4689053177823166 0.6391373150603767 1.0 1.0 29 Q8N183,O43676,Q8IUX1,Q9Y6M9,Q96CU9,Q9NPL8,Q5SW96,O75306,Q86Y39,P00846 10 +Tented upper lip vermilion 0.3462838225653692 0.4684848493132453 0.6394379030714392 1.0 1.0 25 Q6PJG6,Q969N2,Q9Y263,Q6DKJ4,Q10471,Q9Y2B2,Q4J6C6,Q96F07,P30153 9 +Psychogenic non epileptic seizure 0.3421388163507987 0.4657062247031927 0.6414257961754868 1.0 1.0 29 P42858,Q96PZ0,Q02978,O75648 4 +Abnormality of the amniotic fluid 0.3174099940438301 0.4652771468377012 0.6417329982621229 1.0 1.0 92 O75844,O15360,Q14739,Q70HW3,Q04446,Q7LGA3,O43683,Q92766,P21964,Q9UHX1,O43909,Q15058,Q13724,P51114,P04062,Q9Y5P6,Q6NUK1,P23786,Q9Y2B2,O60566,Q15645,P06753,Q15125,Q9UBM7,Q6PGP7,P35453 26 +Abnormality of the musculature of the limbs 0.3626239493108145 0.4648404537309391 0.6420457155262456 1.0 1.0 166 P11047,P12235,Q9NR77,Q15067,P07602,Q9NQ11,Q9Y487,P00846,Q14739,Q7RTS9,P07196,O43909,P51530,Q7LG56,P62857,Q99720,Q9Y5P6,O14979,P31749,Q13126,P35270,P42356,O15270,O60313,Q15125,Q15120,O95140 27 +Abnormal upper motor neuron morphology 0.3991799613927158 0.464001671236319 0.6426465482656503 1.0 1.0 12 P35637 1 +Abnormal retinal vascular morphology 0.3177110502133695 0.4639664291926998 0.6426717978031506 1.0 1.0 56 P17900,Q15555,P38435,Q02978,P21964,O75306,P07602,P00846,P10619,Q96S66 10 +Aplasia hypoplasia involving the femoral head and neck 0.4081362688534451 0.4635757141843996 0.6429517573883259 1.0 1.0 11 O95831,Q99575 2 +Aplasia hypoplasia of the femur 0.3703260039573022 0.4622057858169164 0.643933754526083 1.0 1.0 16 O95831,P15260,Q99575,Q9UHX1 4 +Abnormality of the supraorbital ridges 0.3528166026422648 0.4613542170177197 0.6445444928138895 1.0 1.0 21 Q08J23,Q9Y4W2,P98175,P38159,Q6PGP7 5 +Lactose intolerance 0.63439567047504 0.4612365936171209 0.6446288702416108 1.0 1.0 3 O95394,Q14566 2 +Abnormal peripheral nervous system morphology 0.3635454964735652 0.4603281180157852 0.6452807215374454 1.0 1.0 169 Q5TAQ9,P11047,P12235,Q8IV08,Q9NR77,Q15067,P07602,Q9NQ11,P34897,P00846,Q9Y619,P07196,P41440,Q9UHX1,Q6DKK2,O95721,P51530,Q7LG56,Q99720,Q9Y5P6,P22626,P31749,P42356,O15270,O60313,Q8N2K0,O95831,Q02978,Q15120,O95140,P35637 31 +Absent toe 0.3418920270181705 0.459643994743638 0.6457717750799747 1.0 1.0 28 O75648,P42858,Q96PZ0,Q7LGA3,Q9UHX1 5 +Shallow orbits 0.4114297899843743 0.4577283091656335 0.6471476469209714 1.0 1.0 9 O75844 1 +Tube feeding 0.3078881645675194 0.4573894540049524 0.6473911431217787 1.0 1.0 69 Q99720,O75648,P61978,P37268,Q08J23,Q01105,P07602,P30153,Q92734,Q9UHX1,Q9NZ01,P35637 12 +Increased intracranial pressure 0.3546787633986065 0.4555569028308965 0.6487086401363897 1.0 1.0 19 P07602,P31749,Q9NZ08 3 +Molar tooth sign on mri 0.4674411179602237 0.4549940282623878 0.649113535055382 1.0 1.0 6 O43924,Q10713 2 +Abnormal aortic valve morphology 0.323277458946003 0.4548594119726873 0.6492103845255643 1.0 1.0 43 Q6NUK1,P61978,O75844,P37268,Q6DKJ4,Q15056,P21964,O15360,Q6PGP7,Q9UHX1,P01889,P06280,P04062 13 +Central nervous system cyst 0.3163271011509467 0.4539332633574975 0.6498768613163517 1.0 1.0 57 Q9Y5P6,Q15125,O43505,P23786,Q9UBM7,Q9Y487,Q9UHX1,P00846 8 +Long toe 0.4060400738194178 0.453571495557334 0.6501372734751709 1.0 1.0 11 P23786 1 +Osteomyelitis 0.3725020812504108 0.4503934619433982 0.6524267584193857 1.0 1.0 15 P48643,Q13126,O15270 3 +Mixed hearing impairment 0.4433573442467253 0.4500994415208478 0.6526387394813273 1.0 1.0 7 Q9NWM8 1 +Broad long bones 0.3312270860572894 0.4465721795909085 0.6551839863490556 1.0 1.0 37 O75648,P42858,Q96PZ0,Q6DKJ4,Q7LGA3,Q9UHX1,O43909 7 +Retinal atrophy 0.3380929657522361 0.4464330128576153 0.6552844905067632 1.0 1.0 31 O75648,P42858,Q96PZ0,P51648,P04062 5 +Broad finger 0.3308036005690012 0.4430999988417853 0.6576934060355419 1.0 1.0 37 O75648,P42858,Q96PZ0,Q6DKJ4,Q7LGA3,Q9UHX1,O43909 7 +Abnormal saccadic eye movements 0.3392851279791621 0.4407106712001941 0.6594224701679874 1.0 1.0 28 Q8IV08,Q9NQ11,O75306,O95140,P04062 5 +Impaired distal vibration sensation 0.4629628678911036 0.4385271308734812 0.6610042072476465 1.0 1.0 6 Q5TAQ9 1 +Abnormal cry 0.3843033191161025 0.4373967654065855 0.6618236295246942 1.0 1.0 13 Q06210,Q13510,O60313,P11047 4 +Large face 0.3013831398410513 0.4368113068021441 0.6622481983587849 1.0 1.0 73 Q6PJG6,Q9BUK6,O75648,P61978,P42858,Q96PZ0,Q06210,Q7LGA3,P21964,P31749,O43924,Q9UJX6,O43909,P28482,O95721,Q06787 16 +Neonatal death 0.3698772485580374 0.4357079351174108 0.6630486477560424 1.0 1.0 15 Q14739 1 +Lymphedema 0.3602933054802114 0.4299374667169388 0.6672411302135179 1.0 1.0 17 P31749,P06280,Q14739,P28482 4 +Blepharophimosis 0.3148932489273982 0.4290177659027772 0.6679102957862044 1.0 1.0 53 O75648,O75844,Q9Y619,P42858,Q96PZ0,Q03164,Q08J23,Q7LGA3,Q15555,P38159,Q86W42,P28482 12 +Macrodontia 0.344435732732937 0.4283241628313839 0.6684151294956369 1.0 1.0 23 P42858,Q96PZ0,Q7LGA3,O75648 4 +Acantholysis 0.5474852954415312 0.4267599565391105 0.6695541754062733 1.0 1.0 4 P16615 1 +Abnormal glomerular mesangium morphology 0.3487840535122224 0.4263648497180771 0.6698420103090426 1.0 1.0 20 O95470,P11047 2 +Upper limb spasticity 0.4148372491742339 0.426194912386826 0.6699658243917235 1.0 1.0 8 P35637 1 +Varicose veins 0.4593231448715404 0.4252661304269991 0.6706426809598831 1.0 1.0 6 P04062,P21964 2 +Venous insufficiency 0.4593231448715404 0.4252661304269991 0.6706426809598831 1.0 1.0 6 P04062,P21964 2 +Neoplasm of the tongue 0.4144902919328093 0.4247062523612819 0.6710508253566538 1.0 1.0 8 P49327,P31749 2 +Retinal degeneration 0.3113013099172503 0.4231898773079364 0.6721567317245747 1.0 1.0 61 P50897,O75648,P42858,Q96PZ0,Q7LGA3,P51648,O75503,Q96S66,O60313,P04062 10 +Oral ulcer 0.4036485636407415 0.4222792931515273 0.6728211704603226 1.0 1.0 9 Q13546,P49327,Q9NZ08 3 +Anteriorly placed anus 0.3708702224139518 0.4201384581739409 0.6743843094324231 1.0 1.0 14 Q9Y2B2,Q8IWV7,P53701,Q6NUK1 4 +Aggressive behavior 0.3010627396037813 0.4182924527392015 0.6757333070503422 1.0 1.0 77 Q15125,Q96PZ0,Q9UBM7,P55795,Q9NQ11,P34897,Q9UJX6,O75503,P35270,Q6DKK2 10 +Abnormal pulmonary thoracic imaging finding 0.3389807319478266 0.4178001364464404 0.6760932511239219 1.0 1.0 25 P15260,P21964,Q9NZ08,P01889,P49327,Q86TI2,Q13510,P04062 8 +Abnormal temper tantrums 0.4004997033689773 0.417145894374437 0.6765716975282667 1.0 1.0 10 P04062 1 +Diminished motivation 0.3363395929390425 0.4145948918662597 0.6784384882287169 1.0 1.0 26 P17900,P42858,P35637,Q9NQ11,Q06787,P04062 6 +Abnormal periventricular white matter morphology 0.3232890315090617 0.4131344345512666 0.6795081218823864 1.0 1.0 40 Q9Y5P6,P17900,O75648,Q9NQ11,P07602,O75503,Q9UHX1,O60313 8 +Type ii lissencephaly 0.4743876280779445 0.4124416397312241 0.6800157481734463 1.0 1.0 5 O43505 1 +Abnormal oral frenulum morphology 0.368801513385346 0.4089728309181255 0.6825595996641738 1.0 1.0 14 Q6DKJ4,O43924,O75844 3 +Hyperammonemia 0.3289109732032381 0.4065095512515262 0.6843682405238336 1.0 1.0 35 O43772,P23786,Q9Y619 3 +Poor appetite 0.3642485928697438 0.4044635348956491 0.6858718875303631 1.0 1.0 15 Q70HW3 1 +Neoplasm by histology 0.3213865783290915 0.397591830003053 0.6909310838244687 1.0 1.0 105 P62857,Q92804,Q15555,Q02978,Q01844,Q15392,O75874,P31749,Q6PGP7,Q13126,Q9UJX6,P48735,O60566,P49327 14 +Lower limb spasticity 0.3067461538029355 0.3973432497675833 0.691114358153321 1.0 1.0 86 P04062,Q99720,Q15041,Q9Y619,O95831,Q96CU9,Q9H6K4,O75306,P07602,P00846,Q6DKK2,P42356,O60313,P35637 14 +Increased circulating igg level 0.469860897036451 0.3972135255046087 0.6912100090176212 1.0 1.0 5 P49327 1 +Epidermal acanthosis 0.3856174241192263 0.3970713110366249 0.6913148750708822 1.0 1.0 12 P31749,Q06136,P16615 3 +Emphysema 0.3936761629894378 0.3953703840949737 0.6925695624333348 1.0 1.0 11 Q9UJX6,Q03518 2 +Cutaneous abscess 0.5367746455583435 0.3945338337565858 0.6931869529393466 1.0 1.0 4 P53634,Q13546 2 +Elevated pulmonary artery pressure 0.3355526197723366 0.3942244917366039 0.6934153050328495 1.0 1.0 25 Q8IZA0,O75844,P11047,Q14108,P04062 5 +Mildly elevated creatine kinase 0.3373879150554085 0.3934196056105623 0.6940095915354063 1.0 1.0 24 Q9BUK6,O75648,Q16836,Q06210,Q92734,P09651 6 +Ulnar deviation of finger 0.3970854885682522 0.3928198883013085 0.6944525143227451 1.0 1.0 9 P28482,Q9UBM7 2 +Telangiectasia of the skin 0.3443354964946842 0.3913481498590564 0.6955399126069064 1.0 1.0 19 Q14739 1 +Decreased activity of mitochondrial complex i 0.3220254346101257 0.3910614971265369 0.6957517797785382 1.0 1.0 39 O43676,O75648,Q9UBX3,Q9Y6M9,Q96CU9,Q9NPL8,O75306,Q86Y39,Q70HW3 9 +Alopecia 0.3106318167196037 0.3900454410638631 0.6965029455871781 1.0 1.0 47 Q15125,O75844,P48449,Q8IWV7,Q06136,O15460 6 +Abnormality of extrapyramidal motor function 0.3010815409617574 0.389219806159449 0.6971135531731603 1.0 1.0 80 P04062,Q99720,P42858,P12235,Q9H6K4,Q9NQ11,P07602,P35270,Q6DKK2,P35637,Q7LG56,O14949 12 +Upper extremity joint dislocation 0.3426485132525785 0.3878093860521118 0.698157099027884 1.0 1.0 20 O43909,Q9Y619 2 +Abnormality of the hallux 0.3072482870994287 0.3877970420328886 0.698166234680726 1.0 1.0 62 Q15125,O75648,P42858,Q96PZ0,Q6DKJ4,Q7LGA3,P31749,P30153,Q9UHX1,O95140,P04062 11 +Spinocerebellar tract degeneration 0.5927261797415155 0.3872877030951475 0.6985432281171646 1.0 1.0 2 O00754 1 +Neoplasm of the nervous system 0.3106207454658416 0.3865526454218236 0.6990874211266782 1.0 1.0 51 Q15555,Q01844,Q02978,O75874,P31749,Q9UJX6,P48735 7 +Cyanosis 0.3420984142964323 0.3843758767575133 0.7006998773871873 1.0 1.0 20 O43772,O75844 2 +Unconjugated hyperbilirubinemia 0.6062615256160788 0.3822627031308738 0.7022665163797097 1.0 1.0 3 Q9NSD9 1 +Abnormality of the inner ear 0.3820880113559285 0.3799574270521436 0.7039770176367977 1.0 1.0 12 Q9Y619 1 +Echolalia 0.3919309235876668 0.3780891645410404 0.7053643573721831 1.0 1.0 10 P53701 1 +Visual acuity test abnormality 0.462529508561835 0.3729697451980432 0.7091709617283677 1.0 1.0 5 P31749,P25054 2 +Cardiovascular calcification 0.3887370739076304 0.3725416300670299 0.7094896225864848 1.0 1.0 11 O75844 1 +Progressive neurologic deterioration 0.3370857766523353 0.3694474608311212 0.7117942275416687 1.0 1.0 22 P07602,Q7LG56,P04062,Q9NPL8 4 +Pseudoepiphyses of hand bones 0.4610603853007192 0.3681760543536514 0.7127419640910506 1.0 1.0 5 O95613,O96028 2 +Pseudoepiphyses 0.4610603853007192 0.3681760543536514 0.7127419640910506 1.0 1.0 5 O95613,O96028 2 +Pseudoepiphyses of the metacarpals 0.4610603853007192 0.3681760543536514 0.7127419640910506 1.0 1.0 5 O95613,O96028 2 +Abnormal urine protein level 0.3068163132147743 0.3672833438042245 0.7134076769590192 1.0 1.0 59 P11047,Q02978,Q0IIM8,P09601,O95470,Q14108,P04062 7 +Absent earlobe 0.5993870860556427 0.3639958586668881 0.7158611018787295 1.0 1.0 3 Q02224 1 +Receptive language delay 0.3397030307377912 0.3630248576181893 0.7165863155071439 1.0 1.0 19 P42858,Q96PZ0,O75648 3 +Fever 0.3090077427266872 0.3590999699907873 0.7195203040557048 1.0 1.0 93 P14174,P28070,P61978,Q0IIM8,P23786,Q9NR77,Q9NQ11,P07602,P06280,Q9NZ08,P00846,P49327,Q14739,Q9HC07,Q13510,O15460 16 +Aortic root aneurysm 0.3283097886392894 0.358606293117293 0.7198896383034301 1.0 1.0 26 P42858,Q96PZ0,Q06787,O75648 4 +Neurofibrillary tangles 0.5973143569696996 0.3585725013280216 0.7199149213309457 1.0 1.0 3 O15118 1 +Hemiparesis 0.3434794648352433 0.3576745873049524 0.7205868530337369 1.0 1.0 18 P31749,O60313,Q9NZ08 3 +Weight loss 0.2973501321426349 0.3560150601683406 0.721829286758616 1.0 1.0 79 O75844,P07602,Q06136,O15360,P42858,Q02224,Q7LG56,P04062,Q99720,O95613,P31749,P42892,Q9NZ08,P49327,Q15645,Q02978,Q01844,Q6Y7W6,O15460,P35637 20 +Aplasia hypoplasia of the radius 0.3345434870719667 0.3531379753187524 0.7239850043752205 1.0 1.0 22 P98175,Q9UBM7,Q96AY3 3 +Mediastinal lymphadenopathy 0.4386707157888592 0.3522935847623679 0.7246180987755659 1.0 1.0 6 Q01844 1 +Sparse eyebrow 0.3220128077037185 0.3522137447439105 0.7246779697720027 1.0 1.0 35 P62857,Q15125,P61978,O75844,Q08J23,P48449,Q14574,O60828,P41227 9 +Pericardial effusion 0.3961881232433598 0.3478753501469085 0.7279337981515568 1.0 1.0 8 Q14108 1 +Cavum septum pellucidum 0.3753595457839065 0.3477192166678527 0.7280510633997779 1.0 1.0 12 P28482,Q9UJX6 2 +Abnormal urine cytology 0.3125444860491895 0.3467425075622555 0.7287847726562731 1.0 1.0 42 Q02978,P09601,P49257,Q14108,P04062 5 +Prominent digit pad 0.3303472346071562 0.3464050445679031 0.729038334514513 1.0 1.0 24 P42858,Q96PZ0,P55795,O75648 4 +Abnormality of the skull base 0.3045650442816587 0.3447718304112476 0.7302659121357342 1.0 1.0 59 Q15125,O43505,P23786,Q9UBM7,Q9NPL8,Q9UJX6,Q9Y487,Q9UHX1,Q14739 9 +Thyroid adenoma 0.436227430026154 0.3439366451284503 0.7308939323140349 1.0 1.0 6 P31749 1 +Abnormal renal tubule morphology 0.3276843320313792 0.3407127357864078 0.7333198499823372 1.0 1.0 25 P00846,P23786 2 +Aplasia hypoplasia of the clavicles 0.3486159027441785 0.3393920258684585 0.734314424932244 1.0 1.0 16 Q9Y619 1 +Cerebral hypoplasia 0.3444950599495696 0.3385844412013076 0.7349228051305101 1.0 1.0 17 Q86XL3,Q9UBM7 2 +Abnormality of the nasal dorsum 0.304067042930628 0.335949894020715 0.7369086513674463 1.0 1.0 58 O96028,Q15125,P61978,O75844,O95613,Q8IWV7,Q15645,Q9Y2B2,O43683,Q02224,Q6PGP7,O60566,O95721,P51530 14 +Abnormal circulating pyruvate family amino acid concentration 0.3330378321113321 0.3353105479260805 0.737390837755509 1.0 1.0 21 P00846,Q5XKP0,O75880,Q7LG56 4 +Generalized onset seizure 0.3137628686171371 0.3349215967908563 0.7376842301578419 1.0 1.0 102 Q6PJG6,P61978,Q9Y619,Q08J23,P00374,Q01105,P07602,O60566,Q9UJX6,O75503,O43909,P00846,P28482,Q9NZ01,Q13510,Q14108,P04062 17 +Elevated hemoglobin a1c 0.5874924834636094 0.333419650540556 0.7388175319683163 1.0 1.0 3 Q96MF7,O75431 2 +Decreased specific antibody response to vaccination 0.5872616084125794 0.3328394469320259 0.7392554799227804 1.0 1.0 3 P17812 1 +Abnormal renal pelvis morphology 0.3041786754200342 0.3311091435389596 0.7405620452871431 1.0 1.0 56 Q15125,P61978,Q08J23,Q6DKJ4,Q8IWV7,P98175,O43505,Q9UBM7,P23786,Q8NCH0,O75718,Q9UJX6 12 +Abnormal 5th finger phalanx morphology 0.5856921912596349 0.328909065495893 0.7422244219398961 1.0 1.0 3 Q9UHX1 1 +Abnormality of the endometrium 0.3912170374967217 0.327635056622077 0.7431876123472907 1.0 1.0 8 P31749 1 +Chromosome breakage 0.3710932108985293 0.3275588055614055 0.7432452732932762 1.0 1.0 12 O15360,P31749 2 +Decreased circulating level of specific antibody 0.41139173505333 0.3270463900899429 0.7436327985037612 1.0 1.0 7 P49327,P17812 2 +Multifactorial inheritance 0.361968279258166 0.3243295278454104 0.74568856686599 1.0 1.0 13 P42892 1 +Pes planus 0.295213745783488 0.3218885966567816 0.7475370923639186 1.0 1.0 80 Q9Y5P6,O75648,Q15555,Q9NSE4,Q9Y4W2,Q06210,P55795,O15360,Q9Y487,Q9NWM8,Q9UJX6,P28482,Q7RTS9,Q9UHX1,Q06787 15 +Vascular dilatation 0.2934811260835475 0.3215639915497251 0.7477830265902639 1.0 1.0 71 P06753,Q6ZXV5,Q9Y5P6,O75648,O75844,P61978,P42858,Q96PZ0,Q8IWV7,Q6NUK1,Q7LGA3,Q15056,O95613,P38435,Q9UJX6,P28482,Q06787,O15460 18 +Abnormality of the synovia 0.3040855326858613 0.3206423711166276 0.748481424107863 1.0 1.0 91 O96028,Q9Y5P6,O75844,Q9NSE4,Q9UBM7,P31749,O15360,O75718,Q96AY3,Q9Y487,Q9UHX1,O43909,Q7RTS9 13 +Aplasia hypoplasia of the phalanges of the toes 0.446081551345525 0.3206013365349519 0.7485125246306035 1.0 1.0 5 P35453,Q9Y2B2 2 +Dysmetric saccades 0.4095396996728332 0.3202438405352269 0.7487834917539473 1.0 1.0 7 O95140,O15020 2 +Cutaneous cyst 0.5103759398496273 0.3197020221495576 0.7491942267226448 1.0 1.0 4 P25054,Q9H488,O60716 3 +Epidermoid cyst 0.5103759398496273 0.3197020221495576 0.7491942267226448 1.0 1.0 4 P25054,Q9H488,O60716 3 +Very long chain fatty acid accumulation 0.4452247834514012 0.3179546310646082 0.7505193515298436 1.0 1.0 5 Q5T8D3,P50542 2 +Multicystic kidney dysplasia 0.3311602023415581 0.3169929416920502 0.7512489580031749 1.0 1.0 20 Q6DKJ4,Q9UBM7,O43683,O60566,Q15645 5 +Limb hypertonia 0.314023022575598 0.3155359441228275 0.7523547643867257 1.0 1.0 38 Q14739,Q15125,P35270 3 +Myokymia 0.5785222073246032 0.3112595015973501 0.7556033521651266 1.0 1.0 3 Q9NQ11 1 +Impaired antigen specific response 0.3862158269461909 0.3075708170684194 0.7584089289985714 1.0 1.0 8 P49327,P17812 2 +Nonprogressive 0.4058613558026021 0.3068520757809467 0.7589559683070175 1.0 1.0 7 Q06210 1 +Long fingers 0.2955418636123869 0.3065218704586147 0.759207330486031 1.0 1.0 82 Q15125,Q15555,Q9NSE4,Q9Y4W2,P55795,P23786,P21964,Q8NCH0,P42892,Q06136,Q9UHX1,P28482 12 +Abnormal superior cerebellar peduncle morphology 0.5623685001502934 0.3064265460093838 0.7592798990449132 1.0 1.0 2 Q10713 1 +Elongated superior cerebellar peduncle 0.5623685001502934 0.3064265460093838 0.7592798990449132 1.0 1.0 2 Q10713 1 +Bilateral tonic clonic seizure with generalized onset 0.3768466758420286 0.3049036804774354 0.7604395125420544 1.0 1.0 9 P04062 1 +Abnormality of metacarpal epiphyses 0.4240079467307244 0.3031052998433378 0.761809615340362 1.0 1.0 6 O95613,O96028 2 +Sparse lateral eyebrow 0.4048111882470123 0.3030582869286782 0.7618454423369725 1.0 1.0 7 P61978,Q08J23 2 +Attenuation of retinal blood vessels 0.3763555810688195 0.3028314553825331 0.762018310372407 1.0 1.0 9 P38435 1 +Macrocytic anemia 0.3129415562670851 0.2986348769423165 0.765218651151133 1.0 1.0 37 P62857,P00374,O60313,P41440 4 +Exercise induced myalgia 0.3735076167451311 0.2968769398810395 0.7665604622085016 1.0 1.0 10 P23786 1 +Ineffective esophageal peristalsis 0.4213682330960665 0.294505124909644 0.7683719478643039 1.0 1.0 6 Q9NSE4 1 +Fasciculations 0.3091021926976279 0.2943827496319994 0.7684654470194456 1.0 1.0 40 O95831,P22626,P07602,P07196,Q92734,P09651,Q13510,P51114,P35637 9 +Perseveration 0.372766979082805 0.2936999608151528 0.7689871842559137 1.0 1.0 10 Q13148,Q9BSH4,P35637 3 +Premature skin wrinkling 0.3322504989985543 0.2924475480743556 0.7699444582324446 1.0 1.0 18 O75844 1 +Myoclonus 0.3070100121770048 0.2919002038772865 0.7703629276030217 1.0 1.0 98 P50897,Q9UBX3,Q01105,Q96CU9,Q9NPL8,Q9NQ11,P07602,P00846,Q14108,P42858,P00374,O75503,Q13510,P04062,Q8NI60,Q9Y2B2,P31749,Q9NQZ5,Q6PJG6 19 +Microcornea 0.3168985545876534 0.2893738310457414 0.7722953185649404 1.0 1.0 31 Q8NCH0,Q15125,O43505 3 +Abnormal heart valve morphology 0.2947369058613328 0.2878796584827734 0.773438858259647 1.0 1.0 83 P53701,O75844,P37268,P55795,Q8NCH0,O15360,Q06787,P08236,O00571,Q6ZXV5,P61978,Q15056,P21964,Q9UHX1,O43909,P04062,O96028,Q6NUK1,Q6DKJ4,Q9Y2B2,P06280,P06753,Q6PGP7,P01889,P28482,P41227 26 +Oculomotor apraxia 0.3177688149317051 0.2868080798173302 0.7742592759444604 1.0 1.0 27 O43924,P28482,P35270,P04062 4 +Organic aciduria 0.3104242745683842 0.2865149903839272 0.7744837138372558 1.0 1.0 38 Q16836,P12235,O43772,P23786,Q16134,P48735,O75880 7 +Progressive inability to walk 0.3249413714159195 0.2853352164926275 0.7753873348992211 1.0 1.0 21 P00846,Q7LG56 2 +Abnormal morphology of myocardial trabeculae 0.4335138387484858 0.2826347676838902 0.7774568257574141 1.0 1.0 5 P14923,Q15233,P35609,Q99797 4 +Extra axial cerebrospinal fluid accumulation 0.55214908325819 0.2817108180849406 0.778165258691518 1.0 1.0 2 Q03252 1 +Aplasia hypoplasia of toe 0.3075304943431371 0.2814192899308467 0.7783888244939843 1.0 1.0 40 O75648,P42858,Q96PZ0,Q9UBM7,Q7LGA3,Q9UHX1,Q13510 7 +Abnormal upper limb bone morphology 0.3138809761184106 0.2777774743023514 0.7811831838416678 1.0 1.0 109 O75844,Q96PZ0,O15360,Q96AY3,Q14739,Q7RTS9,Q32P28,O75648,P42858,P98175,Q7LGA3,Q9UHX1,O43909,O96028,Q08J23,Q6DKJ4,P31749,Q9UBM7,O43924 19 +Focal segmental glomerulosclerosis 0.3225691522211258 0.2776714534773958 0.7812645759846397 1.0 1.0 22 O95470,Q14108 2 +Hemifacial spasm 0.494071641627346 0.2770802867352718 0.7817184583514121 1.0 1.0 4 P31749,Q969G3 2 +Distal arthrogryposis 0.4313808301928726 0.2763788359434326 0.7822571103681477 1.0 1.0 5 Q8NCH0 1 +Focal t2 hyperintense brainstem lesion 0.3230597898057023 0.2738817951276362 0.7841754622433164 1.0 1.0 21 Q8N183,O43676,Q9Y6M9,Q96CU9,Q9NPL8,O75306,Q86Y39 7 +Rhabdomyosarcoma 0.3691011677093216 0.272593464016449 0.7851657366961395 1.0 1.0 9 Q15645,O60566,O43683 3 +Kyphosis 0.3446953682664131 0.2709386526778339 0.7864382159348882 1.0 1.0 162 O75844,Q96PZ0,Q9NR77,Q8NCH0,Q96AY3,Q9Y487,Q9UJX6,Q14739,Q7RTS9,Q14108,Q32P28,P42858,Q9NWM8,Q9UHX1,O43909,P51530,P04062,P31749,Q9HC07,Q15125,O95831,Q9UBM7,O95140 23 +Rod cone dystrophy 0.3005158040228427 0.2698821627761573 0.7872509102061178 1.0 1.0 44 Q15555,P38435,Q15067,P00846,Q8N2K0 5 +Decreased serum complement c3 0.5470393748121424 0.2698491289233944 0.7872763249072381 1.0 1.0 2 Q03252 1 +Gastritis 0.3954507209938203 0.2698464623694726 0.7872783764389768 1.0 1.0 7 P49327,Q6PGP7 2 +Abnormalities of placenta or umbilical cord 0.3277422991673607 0.2668363528798924 0.7895951631675768 1.0 1.0 18 O75844,Q9Y2B2,Q6PGP7,O60826,P42771,P35453 6 +Multifocal seizures 0.4277131609288589 0.2657538639872031 0.7904287769951444 1.0 1.0 5 Q6PJG6 1 +Muscular dystrophy 0.3143743982822293 0.2636976571041736 0.7920129010154247 1.0 1.0 27 Q9Y5P6,P22626,O43505,O14979,O60566,P09651,Q15645,P50402 8 +Increased circulating prolactin concentration 0.393564462142159 0.2632896166888862 0.7923273621277 1.0 1.0 7 P31749 1 +Aplasia hypoplasia involving the pelvis 0.3307869715360874 0.2622167261857983 0.793154358805735 1.0 1.0 17 O95831,O96028,Q99575 3 +Spastic paraplegia 0.2973726643094789 0.2621592808538211 0.7931986449173336 1.0 1.0 53 Q15041,Q9Y619,O95831,Q96CU9,O75306,P00846,O60313,P04062 8 +Facial asymmetry 0.3101030090808624 0.2601453172490393 0.7947516828219985 1.0 1.0 35 Q01105,Q8NCH0,O15360,P31749,P30153,Q9UHX1,P28482 7 +Poor head control 0.2888818829669906 0.2594178644052626 0.7953128475901228 1.0 1.0 79 Q8N183,Q5XKP0,Q9Y5P6,O43676,P17900,P11047,P00374,Q06210,O94992,Q9Y6M9,Q96CU9,Q9NPL8,O75306,P07602,Q9NWM8,O75340,Q86Y39,O95721 18 +Abnormality of limb epiphysis morphology 0.3114418795365308 0.2582958696920932 0.7961785736528355 1.0 1.0 33 O96028,O95613,O95831,Q7LGA3,O43909,Q7RTS9 6 +Tongue fasciculations 0.3629257178115561 0.2579417904713449 0.7964518317208584 1.0 1.0 11 O95831,P51114 2 +Abnormality of the phalanges of the toes 0.3219320890341325 0.2574086795768773 0.796863303251186 1.0 1.0 19 Q6DKJ4,O15360,Q7LGA3,O75844 4 +Optic disc hypoplasia 0.4241254449974352 0.2555247850710744 0.798317803102313 1.0 1.0 5 O95721,P25054 2 +Vestibular dysfunction 0.3116779125526415 0.2554470564205239 0.7983778301971935 1.0 1.0 32 P46976,Q02978,P41440,Q9NZ08,P49327,P06280,P0DP25,Q6UN15,O15460 9 +Abnormal peristalsis 0.391194175667237 0.2551171386526966 0.7986326273128133 1.0 1.0 7 Q9NSE4 1 +Focal motor seizure 0.3189022652295233 0.2550589978666716 0.7986775319514812 1.0 1.0 22 O43909,O75503 2 +Transient ischemic attack 0.3909202753216915 0.2541776192651951 0.79935834017051 1.0 1.0 7 O75844 1 +Abnormality of the adrenal glands 0.2956964476339807 0.2537729446882024 0.799670976350294 1.0 1.0 58 O75844,Q02978,O75874,P31749,P48735,O95470 6 +Abnormal rib cage morphology 0.2897705807800046 0.250410087030439 0.8022702297395419 1.0 1.0 81 Q32P28,O75844,Q9Y619,O95831,Q6DKJ4,Q9UBM7,P31749,O75718,Q9UHX1,Q14739,Q7RTS9 11 +Neuronal loss in basal ganglia 0.4223032066646552 0.2503925467189113 0.8022837929360493 1.0 1.0 5 O75306 1 +Hyperpigmentation of the skin 0.3047979477559113 0.2493600401788194 0.8030822923100933 1.0 1.0 100 P53701,O75844,Q96PZ0,P51648,O15360,Q06136,Q9UJX6,Q14739,O75648,P42858,Q8IWV7,Q7LGA3,P04062,O95613,P31749,O60566,Q15645,Q15555,Q6PGP7,P28482 20 +Abnormality of pancreas physiology 0.2946944305329416 0.2482342311030688 0.8039531824388133 1.0 1.0 46 P14174,Q8IWV7,P09601,Q9NZ08,Q9UHX1,Q14739 6 +Duplication of hand bones 0.2915990253641905 0.2461700335796425 0.8055506116210589 1.0 1.0 65 P62857,Q15125,P98175,Q9UBM7,Q15067,P21964,O15360,P34897,O43924,Q9UHX1,O43909,Q14739 12 +Aplasia hypoplasia of the distal phalanges of the hand 0.3089846502339489 0.2454105320126035 0.8061385749489951 1.0 1.0 34 Q6NUK1,O75844,Q969G3,Q6DKJ4,O95613,P38435,O95630,Q9Y2B2,O60826,P28482,P35453,O15111 12 +Palpitations 0.3197625128847101 0.2448923948913763 0.8065397504287055 1.0 1.0 19 Q02978,Q7LG56 2 +Hypermetric saccades 0.549308478653023 0.2447887969268495 0.8066199688251317 1.0 1.0 3 O14773,Q9NXN4 2 +Olivopontocerebellar hypoplasia 0.4054252231778675 0.2443536319585561 0.8069569497402735 1.0 1.0 6 P30153 1 +Abnormal nasolacrimal system morphology 0.3452039113866597 0.2437879957750845 0.8073950178674894 1.0 1.0 13 P53701 1 +Abnormal large intestine physiology 0.3170384750750545 0.2436643413030546 0.8074907925699848 1.0 1.0 22 Q13043,P21964,Q9NQ11,P07602,P28482,P06280,Q06787 7 +Chorea 0.2908130104603178 0.2433455102705069 0.807737751637134 1.0 1.0 83 Q99720,Q01105,Q9H6K4,O75306,P07602,Q9BWD1,P35270,Q9NZ01,P00846,P35637 10 +Gastrointestinal obstruction 0.3304083875183736 0.2414552140682007 0.8092023236772694 1.0 1.0 16 P42892 1 +Centrally nucleated skeletal muscle fibers 0.3868157937775635 0.2402212101960618 0.810158771663096 1.0 1.0 7 P22626,P51114 2 +Deviation of the hallux 0.3065491191476428 0.2400962392667095 0.8102556495885336 1.0 1.0 36 O75648,P42858,Q96PZ0,P31749,P04062 5 +Adducted thumb 0.3106650083773218 0.2389806043721185 0.8111206225125587 1.0 1.0 28 Q8NCH0,P42892,Q86XL3 3 +Episodic hypertension 0.5329125338142551 0.2388163278271297 0.8112480087441958 1.0 1.0 2 O60333 1 +Macule 0.2859402229211129 0.2385181322259401 0.8114792536325028 1.0 1.0 71 O75648,O75844,P42858,Q96PZ0,Q8IWV7,O95613,Q7LGA3,P16615,O43683,O15360,Q06136,P31749,O60566,Q6PGP7,P28482,Q15645 16 +Delusions 0.3170737208471015 0.237884221989457 0.8119708933136285 1.0 1.0 21 Q9UJS0,P42858,Q13144,P21964,P07602,P49770,O43681,O60220,P04062 9 +Acute coronary syndrome 0.3169649778081772 0.237236757799612 0.8124731215268903 1.0 1.0 21 O75844,Q15056,Q9NZ08,P01889,P49327,P06280 6 +Tremor 0.3473508987040321 0.233593292466424 0.815300735540311 1.0 1.0 175 P12235,Q9NR77,Q9NQ11,P07602,Q9UJX6,P00846,Q14108,Q9BUK6,P42858,P07196,O75503,P41440,Q6DKK2,Q7LG56,P04062,Q99720,Q8NI60,Q9H6K4,P31749,P35270,O60313,Q8N2K0,Q9NQZ5,Q6PJG6,O95831,Q02978,Q5T8D3,O75306,O43924,O95140,Q15120,Q5JRX3,P35637 33 +Abnormal odontoid tissue morphology 0.2932793019345167 0.2326556170228313 0.8160288359668169 1.0 1.0 47 P53701,Q9UBM7,Q02224,P51648,P21964,P31749,Q96AY3,Q9HC07 8 +Aplasia hypoplasia affecting the eye 0.3098573111419072 0.2317406069444675 0.8167394899950637 1.0 1.0 109 P53701,P11047,P37268,O15360,P30153,O60828,Q86YV9,P61978,O43505,Q15056,Q7LGA3,O43683,P21964,P07196,Q9UHX1,O95721,O15111,O96028,Q9Y5P6,O60566,Q15645,Q15125,Q15555,Q02978,Q9UBM7,O43924 26 +Truncal ataxia 0.3250760704479742 0.2313517047502534 0.8170415814231293 1.0 1.0 17 P34897,O75503 2 +Abnormal mitochondrial morphology 0.3342108518893782 0.2306489405465538 0.8175875434767805 1.0 1.0 14 P35637 1 +Abnormal social behavior 0.2841993641173833 0.2304524570300865 0.8177402030415832 1.0 1.0 72 Q8N183,Q5XKP0,O43676,Q5KU26,Q15125,O94992,Q15056,Q96CU9,Q9Y6M9,Q9NPL8,Q15067,P07602,O75306,Q9UJX6,Q9UHX1,O43909,Q06787,Q86Y39 18 +Thickened skin 0.3068112827851004 0.2299980091802813 0.8180933166970803 1.0 1.0 105 P28070,Q15125,O75844,P48449,Q15800,P31749,Q06136,Q9NWM8,Q14739,O95470,O15270,P04062 12 +Neurodegeneration 0.3075572665987739 0.2297381558416016 0.8182952437214983 1.0 1.0 33 Q15165,P17900,Q92804,P42858,Q6DKK2,P35637 6 +Hypoglycemic coma 0.3654561694090237 0.2278268488523573 0.8197808531565243 1.0 1.0 8 Q16836,Q16134 2 +Migraine 0.3131704603301359 0.2269670018142104 0.820449401324743 1.0 1.0 23 P12235,Q9NZ08,P49327,Q7LG56,O60313 5 +Bulbous nose 0.2938832739127506 0.2262534637381485 0.8210042904553465 1.0 1.0 45 O00571,P23786,Q9Y2B2,P21964,P38159,Q96A33,P42892,O43909,O60828,Q06787 10 +Duodenal atresia 0.3826346204068786 0.2262452928963913 0.8210106451012935 1.0 1.0 7 Q15645,O60566 2 +Slurred speech 0.3564722352571718 0.2257569301322616 0.8213904770389373 1.0 1.0 10 Q9Y487 1 +Tissue ischemia 0.3149993823092275 0.2255749624524548 0.8215320160214903 1.0 1.0 21 O75844,Q15056,Q9NZ08,P49327,P06280,O15460 6 +Congenital diaphragmatic hernia 0.310104802500467 0.2248444406729274 0.8221002924479857 1.0 1.0 25 P62857,O96028,P53701,Q9UBM7,O15111 5 +Cerebral visual impairment 0.291213240112528 0.2247737539969055 0.8221552849131708 1.0 1.0 62 P37268,P12235,Q96CU9,P30153,Q9NZ01,Q7LG56 6 +Gingival bleeding 0.3484472542790857 0.2247490574366477 0.822174498425059 1.0 1.0 12 Q14108,P04062 2 +Laryngomalacia 0.326916527125297 0.2233240242202392 0.8232833307525182 1.0 1.0 16 O95613,Q92766,P21964,P07602,P35453 5 +Abnormality of hepatobiliary system physiology 0.2906043083869503 0.2223574741206028 0.824035613873731 1.0 1.0 85 Q8N511,Q5XKP0,O75648,Q9Y619,Q16836,Q8IWV7,O43772,P23786,O75306,O15118,Q6PGP7,P00846,O15460,P04062 14 +Spastic gait 0.3096915271475039 0.2221925652213519 0.8241639815670285 1.0 1.0 25 P48643,P34897,Q15041,Q9Y619 4 +Choreoathetosis 0.3072745047401339 0.2204800450943735 0.8254973117307227 1.0 1.0 31 P00846,P35270 2 +Atrial arrhythmia 0.3538533670919457 0.219845677265397 0.8259913444492191 1.0 1.0 11 P12235,Q7LG56 2 +Primitive reflex 0.3628346614400757 0.2181989314054335 0.827274117639647 1.0 1.0 8 Q9NQ11 1 +Reduced tendon reflexes 0.3480816766506289 0.2179570210973145 0.8274625985391806 1.0 1.0 180 Q5TAQ9,P11047,Q9NSE4,P12235,Q9NR77,Q15067,P07602,Q96AY3,P00846,Q9BUK6,O43505,P07196,P41440,O43909,O95721,Q7LG56,P51114,P04062,Q99720,Q9Y5P6,Q15041,Q9H6K4,O14979,Q9NYY8,O60313,Q8N2K0,O95831,Q15120,O95140,P35637 30 +Small earlobe 0.3623711518019797 0.2165076398410587 0.8285920706520207 1.0 1.0 8 P98175,P10586,P21964 3 +Secondary microcephaly 0.2850516985999947 0.2161796382240758 0.8288477246337185 1.0 1.0 79 P50897,Q6PJG6,Q5XKP0,P00374,P55795,Q5T8D3,Q96CU9,O95721,Q9Y487,Q9UHX1,O43909,Q9HC07 12 +Abnormal circulating proteinogenic amino acid derivative concentration 0.3111342402726838 0.2144583638632988 0.8301896324131603 1.0 1.0 23 P00846,Q5XKP0,O75880,Q7LG56 4 +Abnormal endocardium morphology 0.3217741571679829 0.2137899004105761 0.8307109011831746 1.0 1.0 17 Q15056,Q9NZ08,P49327,P06280,P04062 5 +Abnormal chorioretinal morphology 0.306040272341638 0.2096371710889328 0.8339508658885564 1.0 1.0 30 P53701,O43505,Q9Y619 3 +Abnormal choroid morphology 0.306040272341638 0.2096371710889328 0.8339508658885564 1.0 1.0 30 P53701,O43505,Q9Y619 3 +Abnormality of lower limb joint 0.3480610727421012 0.2082527026893025 0.835031659737703 1.0 1.0 182 O75844,P37268,P11047,Q9NSE4,Q9NR77,P07602,O15360,Q96AY3,Q9Y487,Q9UJX6,Q7RTS9,Q9Y619,P42858,Q7LGA3,P21964,Q9UHX1,O43909,Q13510,O96028,Q9Y5P6,Q15041,Q06210,P23786,Q9Y2B2,P31749,O75718,Q15125,O95831,Q86XL3,Q9UBM7,O95140 31 +Neoplasm of striated muscle 0.3519276645111583 0.2075244689182075 0.835600285157952 1.0 1.0 10 Q15645,O60566,O43683 3 +Abnormal mitral valve physiology 0.2972978291494686 0.2074631273985802 0.835648186271011 1.0 1.0 41 P53701,O75844,P09493,O75306,Q9NZ08,P49327,P04062 7 +Retinal dystrophy 0.2908957208457302 0.2072734350852738 0.8357963193718714 1.0 1.0 58 P53701,Q15555,P38435,O43505,Q15067,P00846,Q8N2K0 7 +Erythema 0.3059001715360741 0.2070066267331727 0.8360046832085883 1.0 1.0 27 P53701,Q15125,Q9Y2B2,P51648,P07858,Q06136 6 +Hypoplasia of the iris 0.3926630943665373 0.2065771109779919 0.8363401374724657 1.0 1.0 6 Q7LGA3,P11047 2 +Axial muscle weakness 0.3926496236626441 0.206538414456769 0.83637036113961 1.0 1.0 6 P11047 1 +Reduced forced expiratory volume in one second 0.5160805530507967 0.205286044308935 0.837348646898999 1.0 1.0 2 Q96J02 1 +Breathing dysregulation 0.528860573428886 0.2037520654177023 0.8385472532093015 1.0 1.0 3 O75380 1 +Fetal akinesia sequence 0.3915436667814358 0.2033700810286425 0.838845783029408 1.0 1.0 6 P04062 1 +Epiretinal membrane 0.5277074268395111 0.2015774399190737 0.8402470835093803 1.0 1.0 3 P04439 1 +Thyroiditis 0.3581672699516773 0.2013223943333719 0.8404464928912336 1.0 1.0 8 P49327,P31749 2 +Nuclear cataract 0.3907952246473227 0.2012357208592926 0.8405142615551426 1.0 1.0 6 P08670,Q99797 2 +Abnormality of upper limb epiphysis morphology 0.3193554561264606 0.201064400788208 0.8406482175755772 1.0 1.0 17 O95613,O96028,Q7RTS9 3 +Paroxysmal involuntary eye movements 0.3097948137674468 0.2000558976128191 0.8414368646599746 1.0 1.0 22 Q8N183,O43676,Q9Y6M9,Q96CU9,Q9NPL8,O75306,Q86Y39 7 +Heinz bodies 0.5127742711151293 0.1991451710387566 0.8421491874329297 1.0 1.0 2 O14936 1 +Paraplegia 0.2904780670766765 0.1985579858400422 0.8426085215774286 1.0 1.0 55 Q15041,Q9Y619,O95831,Q96CU9,O75306,P00846,O60313,P04062 8 +Broad phalanx of the toes 0.3740419767646237 0.1983186825358992 0.8427957354302049 1.0 1.0 7 Q6DKJ4,P35453,Q7LGA3 3 +Proptosis 0.2878978376660909 0.1965122662848661 0.844209232736794 1.0 1.0 63 O96028,Q32P28,P61978,O75844,Q6DKJ4,Q9UBM7,O15360,P31749,O75718,Q6PGP7,O43909 11 +Cafe au lait spot 0.290046480679169 0.1945465416875168 0.8457479568079367 1.0 1.0 52 O75648,P42858,Q96PZ0,Q8IWV7,O95613,Q7LGA3,O15360,P31749,Q6PGP7,O60566,P28482 11 +Confetti like hypopigmented macules 0.5100691313495725 0.1942299825542013 0.8459958071995148 1.0 1.0 2 Q15233 1 +Hypomelanotic macule 0.5100691313495725 0.1942299825542013 0.8459958071995148 1.0 1.0 2 Q9H488 1 +Focal cortical dysplasia type ii 0.5100691313495652 0.194229982554188 0.8459958071995253 1.0 1.0 2 P42345 1 +Hemimegalencephaly 0.5100691313495652 0.194229982554188 0.8459958071995253 1.0 1.0 2 P42345 1 +Renal angiomyolipoma 0.5100691313495593 0.1942299825541775 0.8459958071995335 1.0 1.0 2 Q03426 1 +Insulin resistance 0.3144203005146252 0.1933881471090672 0.8466549974601345 1.0 1.0 18 O75844 1 +Intestinal polyp 0.309476879907738 0.1932478933203735 0.84676483213462 1.0 1.0 21 O43683,P31749,P42892,O60566,P42771,Q15645 6 +Esophageal carcinoma 0.5231509320504921 0.1931323790850498 0.8468552951596828 1.0 1.0 3 P25054,P42224 2 +Amenorrhea 0.3003427103945971 0.1927383160578079 0.8471639141518659 1.0 1.0 36 P31749,Q16740 2 +Biliary atresia 0.5091674180943817 0.1926134217366184 0.8472617327379497 1.0 1.0 2 Q10713 1 +Abnormal leukocyte physiology 0.2834891172836566 0.1925497878439927 0.8473115723973834 1.0 1.0 69 Q9UJS0,P14174,P28070,P78536,P02786,Q13546,P15260,P17812,Q13043,Q92766,P21964,Q9Y2Q5,Q6PGP7,P09601,O43909,P49327,Q14108,P04062 18 +Autophagic vacuoles 0.5088668470093303 0.1920769940751099 0.847681895437099 1.0 1.0 2 Q9Y5L0 1 +Arteriovenous malformation 0.3549191372465897 0.1897836893473273 0.8494786376230463 1.0 1.0 8 O15360,P31749 2 +Abnormality of dental morphology 0.2802935661309535 0.187547812987075 0.8512311393447392 1.0 1.0 72 O75648,Q6NUK1,Q9Y619,P42858,Q96PZ0,Q8IWV7,O95613,Q7LGA3,Q15056,Q9Y2B2,P04080,Q15555,Q9UBM7,Q96A33,Q9BUR4,Q9Y487,P28482,O60828 18 +Increased circulating igm level 0.3541572568055195 0.1871021989864992 0.8515805040642699 1.0 1.0 8 Q96AX1,P15260,Q13043,P49327 4 +Cutaneous syndactyly 0.3395621119890507 0.1866255330299975 0.8519542459936116 1.0 1.0 12 Q9Y619 1 +Abnormality of globe size 0.2820703049391425 0.1865446599119666 0.8520176598967897 1.0 1.0 70 Q9Y5P6,P53701,Q9BUK6,Q15125,Q15555,O43505,O43683,P21964,O15360,P31749,O43924,O60566,Q9UHX1,O60828,Q15645,O15111 16 +Emg myopathic abnormalities 0.3015502314600333 0.1862097334172578 0.8522802912899294 1.0 1.0 33 Q9BUK6,P46976,P12235,P22626,P07196,Q7LG56,P09651,P50402,P51114 9 +Retinal vascular tortuosity 0.316472948365668 0.1860577679726783 0.8523994598445799 1.0 1.0 17 O75306,P00846,P21964 3 +Joint swelling 0.3851825943118551 0.185484476098334 0.8528490552798131 1.0 1.0 6 P14174 1 +Axonal regeneration 0.4524778701587338 0.1823586611624483 0.8553012654078329 1.0 1.0 4 P07196,P19367 2 +Preaxial foot polydactyly 0.4523216279842622 0.1820431468562685 0.8555488652947405 1.0 1.0 4 O96028,P35453 2 +Abnormality of pelvic girdle bone morphology 0.335204417231285 0.1814326993386675 0.856027954407655 1.0 1.0 158 O75844,Q9NSE4,Q96PZ0,O15360,P30153,Q96AY3,Q9Y487,Q14739,Q7RTS9,Q8IZA0,O75648,P61978,Q9Y619,P42858,Q7LGA3,Q02224,Q9UHX1,O43909,O96028,Q9Y5P6,Q6DKJ4,O95613,Q9Y2B2,P31749,O75718,Q15125,O95831,Q9UBM7,Q99575,O15228 30 +Hypolipidemia 0.502254283137975 0.1805822719002712 0.8566954720731417 1.0 1.0 2 Q10471 1 +Hypotriglyceridemia 0.502254283137975 0.1805822719002712 0.8566954720731417 1.0 1.0 2 Q10471 1 +Obstructive sleep apnea 0.3378209380393001 0.1793185900884894 0.8576875506512962 1.0 1.0 12 Q96A33,P51530,P51114 3 +Aplasia hypoplasia of the tongue 0.4483282674716293 0.1740848695462526 0.8617987639889597 1.0 1.0 4 Q9UBM7 1 +Microglossia 0.4483282674716293 0.1740848695462526 0.8617987639889597 1.0 1.0 4 Q9UBM7 1 +Lethargy 0.2838063583189265 0.1739603199669234 0.8618966467629758 1.0 1.0 82 P62857,O43676,P20674,Q9Y619,Q16836,P12235,O43772,P23786,Q96CU9,Q9NPL8,O75306,Q9NQ11,Q7LG56 13 +Abnormal size of the palpebral fissures 0.294268415714892 0.1736536981937191 0.8621376280261461 1.0 1.0 95 Q5KU26,O75844,Q96PZ0,P55795,O15360,O75648,P61978,Q9Y619,P42858,Q03164,P98175,Q15056,Q7LGA3,Q9UHX1,Q08J23,Q6DKJ4,O95613,O94992,Q9Y2B2,Q15555,P38159,Q86W42,P28482 23 +Zonular cataract 0.336252924545726 0.1727861329099809 0.8628195374308774 1.0 1.0 12 P08670,Q9H6K4,Q99797 3 +Nasal regurgitation 0.4968440036068628 0.1716130423209978 0.8637417532901677 1.0 1.0 2 Q9BUF5 1 +Apneic episodes precipitated by illness fatigue stress 0.4968440036068616 0.1716130423209958 0.8637417532901692 1.0 1.0 2 P08559 1 +Abnormal sweat gland morphology 0.4464698680743088 0.1704510080240115 0.8646554603972927 1.0 1.0 4 O75844 1 +Fatiguable weakness of proximal limb muscles 0.4458843262715987 0.1693152558035979 0.8655486768283902 1.0 1.0 4 Q92734 1 +Lumbar scoliosis 0.5093205051112324 0.1689507369776814 0.8658353904419673 1.0 1.0 3 P27635,P21281 2 +Central hypoventilation 0.3642278335412869 0.1677961823245509 0.8667436259811299 1.0 1.0 7 Q8N183,O75306 2 +Hypotension 0.3000101552446597 0.1677534419287417 0.8667772512880023 1.0 1.0 28 P07602,O43772 2 +Polycystic kidney dysplasia 0.3127812190754913 0.167100675702011 0.8672908343569488 1.0 1.0 17 Q6PGP7,P23786,Q16134 3 +Abnormality of the plantar skin of foot 0.2857893136087021 0.1666079281588745 0.8676785551280686 1.0 1.0 47 P61978,Q9Y2B2,P09493,P31749,Q06136,P07858,Q9Y487,P16615,O95721 9 +Talipes valgus 0.3895908543923045 0.1659488062628399 0.8681972381094449 1.0 1.0 5 Q9HD42,Q15233,O00754,Q9H2M9 4 +Abnormal aortic valve cusp morphology 0.2993625341333964 0.1658999233555516 0.8682357078122362 1.0 1.0 26 Q6NUK1,P61978,P37268,Q6DKJ4,Q15056,Q6PGP7,Q9UHX1 7 +Hyperlordosis 0.2864359491110782 0.1629278385136127 0.8705752517235159 1.0 1.0 51 P06753,Q9Y5P6,P09651,Q9NSE4,Q06210,P55795,Q15056,P22626,Q99575,P51530,O95140,O43909,P28482,O75340,Q7RTS9,P50402 16 +Deep palmar crease 0.3272766715768752 0.1628545061369453 0.870632991372345 1.0 1.0 13 P98175,Q9Y487,P61978 3 +Aplasia hypoplasia of the uvula 0.3625865103602871 0.1628404558853527 0.8706440541852913 1.0 1.0 7 Q6DKJ4 1 +Muscle fibrillation 0.3175643476667638 0.1627977310384714 0.8706776948052404 1.0 1.0 15 O95831,P51114,Q92734 3 +Abnormal 2nd finger morphology 0.3765141198363925 0.1620613815026213 0.8712575172133952 1.0 1.0 6 Q9H6K4 1 +Germ cell neoplasia 0.339204360838359 0.1611703431412827 0.8719592384683497 1.0 1.0 11 P31749 1 +Abnormality of the pituitary gland 0.2832318763109259 0.1605144049169774 0.8724758752664747 1.0 1.0 65 Q9BUK6,Q9NSE4,O75874,Q4J6C6,P31749,P48735,P42356,Q7LG56 8 +Abdominal pain 0.2922131382709488 0.1593924300712677 0.8733597025960642 1.0 1.0 94 P14174,P04062,Q02978,Q01844,P23786,Q0IIM8,P42892,Q9NZ08,O15460,Q70HW3,Q7LG56,Q14108,P35637 13 +Midface retrusion 0.2807754537485227 0.1589065225837724 0.8737425217178278 1.0 1.0 80 P62857,Q15125,P53701,O95831,Q9NSE4,Q6DKJ4,P55795,Q9Y487,Q14739,Q9HC07 10 +Bilateral polymicrogyria 0.3458766411064591 0.1585897843116642 0.8739920778698265 1.0 1.0 8 P42356 1 +Abnormal tricuspid valve morphology 0.3260774653592613 0.1576588126356478 0.8747256572544524 1.0 1.0 13 Q6DKJ4,P53701 2 +Preaxial hand polydactyly 0.3322193118911669 0.1561947914685927 0.8758794821544309 1.0 1.0 12 O43909,O96028,Q9UHX1 3 +Aplasia hypoplasia involving forearm bones 0.2989518224159226 0.1546473910718816 0.8770993067224462 1.0 1.0 25 P98175,Q9UBM7,Q96AY3 3 +Increased muscle fatiguability 0.4371824883787687 0.1529584461940791 0.878431044732626 1.0 1.0 4 Q7LG56 1 +Generalized hypopigmentation 0.3379249455865607 0.151688507377742 0.8794326220594235 1.0 1.0 9 Q6PGP7 1 +Cortical thickening of long bone diaphyses 0.4836188758641417 0.1513256778445332 0.8797188145306876 1.0 1.0 2 O00754 1 +Thickened cortex of long bones 0.4836188758641417 0.1513256778445332 0.8797188145306876 1.0 1.0 2 O00754 1 +Abnormal circulating igm level 0.3094361977576325 0.1501889498455355 0.8806155437556558 1.0 1.0 17 Q969N2,P15260,Q13043,Q9Y2Q5,O43909,P49327,Q13724 7 +Infantile spasms 0.2968384751868395 0.1499314957932003 0.8808186625244825 1.0 1.0 32 Q9UBX3,Q9UJX6,P00846,P28482,Q13510,P42356 6 +Proximal muscle weakness in lower limbs 0.3022865115746075 0.1494226224671048 0.8812201619663182 1.0 1.0 20 P12235,O95140,Q7LG56 3 +Progressive extrapyramidal movement disorder 0.4350551880167942 0.1491090424411452 0.8814675908229406 1.0 1.0 4 Q9NQ11 1 +Somatic mutation 0.2841772519772969 0.1467911221578543 0.8832968922662192 1.0 1.0 49 Q92804,P30154,Q01844,O75874,Q92733,P31749 6 +Cranial hyperostosis 0.3231953861479726 0.1452922322880665 0.8844801473867374 1.0 1.0 13 P31749,P22626 2 +Nocturnal seizures 0.4791103095882305 0.1449347554157049 0.8847623852907243 1.0 1.0 2 Q01082 1 +Spontaneous abortion 0.4791103095882129 0.1449347554156805 0.8847623852907436 1.0 1.0 2 P50570 1 +Abnormal tongue morphology 0.2753115962918261 0.1439449487611165 0.8855439412854453 1.0 1.0 73 O75844,O60828,O75648,P61978,P98175,Q7LGA3,Q15056,P07196,O15111,Q9Y5P6,Q6NUK1,Q6DKJ4,P31749,P42356,Q9UBM7,Q99575,Q96A33,O43924,P67870,P28482,O15460 21 +Urinary glycosaminoglycan excretion 0.3559980308628368 0.1433913439478737 0.8859811188616455 1.0 1.0 7 P04066,Q96AX1,P54802,P08236 4 +Cirrhosis 0.2901170734632484 0.1412277150073694 0.8876900520889739 1.0 1.0 40 Q14739,Q7LG56,Q14108,P04062 4 +Low set posteriorly rotated ears 0.2780851421185113 0.1384654335725023 0.8898725864414883 1.0 1.0 79 O96028,P37268,Q6DKJ4,Q15555,P98175,Q9UBM7,Q15392,Q08J23,Q8NCH0,Q4J6C6,O43924,O60566,P28482,P04062 14 +Dilatation of the cerebral artery 0.3329952802190945 0.1374582194050154 0.8906686152859487 1.0 1.0 11 O95613,P38435,P10253,Q9NSD9 4 +Abnormal preputium morphology 0.3326643563885932 0.1341664789761044 0.8932709321186834 1.0 1.0 10 O15360,Q9UJX6 2 +Abnormality of blood circulation 0.2751243224599269 0.1341058970037295 0.8933188366333551 1.0 1.0 76 O75844,Q02978,P23786,P31749,Q9Y487,Q9NZ08,P49257,Q14739,P04062 9 +Pharyngitis 0.4861983570369355 0.1334201562515654 0.8938611055304251 1.0 1.0 3 O15460 1 +Pulmonary cyst 0.3647110787457289 0.1320007051195851 0.8949837340249205 1.0 1.0 6 P31749 1 +Abnormality of skin adnexa physiology 0.2855226975843728 0.1314485557866748 0.8954204798919965 1.0 1.0 43 P61978,P04080,Q9Y263,O14936,Q02978,O15269,P07858,Q9BUR4,Q9H0B6,P35270,P01889,O15460,P06280,O15270 14 +Type ii transferrin isoform profile 0.4846662657847242 0.1312813564649657 0.8955527395259004 1.0 1.0 3 O75787,Q9H9E3 2 +Hyposmia 0.3197024266442093 0.1305377564148347 0.8961409843871966 1.0 1.0 13 Q9NQ11,P04062 2 +Abnormality of the upper arm 0.296991195154829 0.1302193051676376 0.8963929213115074 1.0 1.0 23 P48651,O00116,O14979,O15228,Q7RTS9,P50402 6 +Specific learning disability 0.2729990819824881 0.1297729806493787 0.8967460404304561 1.0 1.0 74 P53701,Q9Y619,P42858,P09651,P22626,O43505,Q9Y4W2,Q9H6K4,P21964,Q86W42,P42356,Q9UJX6,O43909,Q06787,P35637 15 +Achilles tendon contracture 0.3194783808864222 0.1296002760617848 0.8968826848240568 1.0 1.0 13 Q8TD16,Q08J23,O60313,P50402,Q8N2K0 5 +Hemolytic anemia 0.2933883080986715 0.128455231033285 0.8977887250952152 1.0 1.0 33 P09601,P41440 2 +Aganglionic megacolon 0.2944924565319342 0.1274431765851096 0.8985896448469457 1.0 1.0 25 Q9UBM7,P21964,O15360,P42892,Q9UJX6 5 +Focal non motor seizure 0.3310404913580747 0.1272467162611113 0.898745131636832 1.0 1.0 9 P42356 1 +Renal cell carcinoma 0.2944263219560054 0.1270437411997882 0.8989057785405548 1.0 1.0 25 Q92733,Q02978,P31749 3 +Abnormal lymphocyte morphology 0.2892373083306105 0.1210276111966203 0.9036691653697866 1.0 1.0 38 P28070,P17812,Q6PGP7,O43909,O95470 5 +Pseudobulbar signs 0.3285704255449048 0.1210108719917247 0.9036824238768056 1.0 1.0 11 P42356 1 +Abnormal fingertip morphology 0.2923102661435252 0.1209585391974339 0.903723874926856 1.0 1.0 33 O75648,O75844,P42858,Q96PZ0,P55795,Q7LGA3 6 +Large forehead 0.36880026210576 0.1203801976947175 0.90418197726951 1.0 1.0 5 Q06787 1 +Narrow iliac wing 0.4177443609022597 0.1199744485285098 0.90450338885434 1.0 1.0 4 P51812,Q15436,P50542 3 +Abnormality of coagulation 0.2809225434805502 0.1195975547554975 0.9048019568437076 1.0 1.0 61 Q9Y619,Q16836,O75874,Q9Y487,P48735,P49257 6 +Abnormality of bone mineral density 0.3183241361624856 0.1190802257858131 0.9052117967980176 1.0 1.0 137 Q15125,Q32P28,O75844,O95831,Q9NSE4,Q15392,P07602,Q13126,Q96AY3,Q9Y487,Q9NWM8,Q14739,Q9HC07,Q7LG56,Q14108,P04062 16 +Abnormal t cell morphology 0.3056986459296392 0.1185765997278891 0.9056108052442726 1.0 1.0 16 O43909,P17812 2 +Deformed tarsal bones 0.4559663360384841 0.1162004989546036 0.9074936413240556 1.0 1.0 2 O75787 1 +Corticospinal tract hypoplasia 0.453561767357977 0.1135937295136048 0.9095598582994044 1.0 1.0 2 Q13045 1 +Cerebellar cyst 0.2851545759128736 0.1102142138333629 0.912239489939512 1.0 1.0 41 Q9Y5P6,Q15125,O43505,P23786,Q9UBM7,Q9Y487 6 +Toe syndactyly 0.2791859314934337 0.1101204573900287 0.9123138441734602 1.0 1.0 63 Q15125,P37268,Q6DKJ4,Q9UBM7,P11233,O15360,P34897,O43924,Q9UJX6,Q9UHX1,P28482 11 +Paraplegia paraparesis 0.2788307718132775 0.1096099779011031 0.9127186971223448 1.0 1.0 83 P04062,Q15041,Q9Y619,O95831,Q96CU9,Q9H6K4,O75306,P00846,Q6DKK2,P42356,O60313,P35637 12 +Aplasia hypoplasia involving bones of the feet 0.2719803952076371 0.1090345290216201 0.9131751033907656 1.0 1.0 75 O96028,O75648,Q08J23,P42858,Q96PZ0,Q9Y4W2,Q9UBM7,Q7LGA3,Q02224,Q9UHX1,Q06787,Q13510,Q7RTS9 13 +Aplasia cutis congenita of scalp 0.3304912051462151 0.1088578347063741 0.9133152508597092 1.0 1.0 8 Q8IWV7 1 +Prolonged qtc interval 0.4670806739955245 0.1086164484037718 0.9135067140031286 1.0 1.0 3 P0DP25 1 +Abnormal morphology of the radius 0.303440221031903 0.1080359616713365 0.9139671658557214 1.0 1.0 16 P98175,Q32P28 2 +Abnormal tracheal morphology 0.2847072771780329 0.106709819186835 0.9150191925055058 1.0 1.0 41 Q15125,O95613,Q9UBM7,Q15056,O15360,O43909,Q14739 7 +Abnormality of primary teeth 0.3031353711661567 0.1066229032147352 0.9150881480217607 1.0 1.0 16 Q8IWV7,O75844,P61978 3 +Abnormality of the musculature of the thigh 0.3246245641724132 0.1052897511707287 0.9161458951532429 1.0 1.0 9 O14979,P07196 2 +Abnormal shape of the frontal region 0.2999401542644349 0.1037818790116549 0.9173424472593336 1.0 1.0 111 O96028,Q15125,P20674,Q9Y619,Q6DKJ4,Q15392,Q9Y2B2,Q15067,Q4J6C6,O43924,O15360,Q6PGP7,O60566,Q9Y487,O43909,Q14739,Q06787 17 +Toe clinodactyly 0.2904321460433533 0.103146807670727 0.9178464559624746 1.0 1.0 25 P42858,Q96PZ0,O75648 3 +Abnormality of the upper respiratory tract 0.2969784285783926 0.102920228557366 0.9180262828878454 1.0 1.0 107 Q15165,P28070,Q86YV9,Q13510,Q92804,O95613,Q9UBM7,Q03518,P21964,P07602,Q9UHX1,O43909,Q06787,Q14739,Q7RTS9,O15460,P35637 17 +Abnormal tongue physiology 0.2967683379975457 0.1021209428429775 0.918660677931468 1.0 1.0 18 O95831,Q9NQ11,P51114 3 +Severe muscular hypotonia 0.289463343736902 0.0985552901180836 0.9214913704382908 1.0 1.0 31 O95831,O43505,Q9NWM8 3 +Cleft soft palate 0.2786945393496783 0.0982086161821781 0.9217666408170816 1.0 1.0 61 Q9Y619,O43505,Q15392,P34897,Q6PGP7,Q9NWM8 6 +Neoplasm of the genitourinary tract 0.2700585026688105 0.0975163530671704 0.9223163482529864 1.0 1.0 74 P62857,Q01844,Q02978,O75874,Q92733,P31749,Q9UJX6,P48735 8 +Focal tonic seizure 0.4370303576795959 0.0974920660129472 0.9223356346218958 1.0 1.0 2 Q00577 1 +Rimmed vacuoles 0.2983581391947879 0.0961104128568824 0.9234328813305744 1.0 1.0 17 O14979,P22626,P09651 3 +Abnormality of the umbilical cord 0.3210566721788411 0.0933353213359693 0.9256371721773742 1.0 1.0 10 P35453,Q9Y2B2,O75844 3 +Failure to thrive in infancy 0.2868477510693155 0.0930165676771879 0.9258903991824696 1.0 1.0 36 P37268 1 +Hypertensive crisis 0.3478043066304491 0.0927877268824273 0.9260722014734104 1.0 1.0 6 P01889,P21964 2 +Aphasia 0.2818534820295234 0.0925745306272333 0.9262415784526384 1.0 1.0 42 P53701,O75648,P42858,Q96PZ0,P22626,Q7LGA3,P21964 7 +Abnormal cortical bone morphology 0.2967978052251923 0.0887459015068363 0.9292838522981726 1.0 1.0 17 Q86XL3 1 +Hypoplastic nipples 0.3011619511052032 0.087922912955994 0.9299379452206692 1.0 1.0 15 Q9Y2B2,Q8IWV7,P10586,Q6NUK1 4 +Severe hearing impairment 0.4241058010219366 0.0869953340114575 0.930675220966778 1.0 1.0 2 P21281 1 +Abnormal electrophysiology of sinoatrial node origin 0.3026962394850142 0.0868506794241351 0.9307902034257576 1.0 1.0 14 P06753,Q02978,P0DP25 3 +Abnormality of small intestinal villus morphology 0.3349357822697201 0.0862095379139766 0.9312998487788522 1.0 1.0 7 Q6PGP7 1 +Obsessive compulsive behavior 0.2819852447148429 0.0855164416195576 0.9318508248298 1.0 1.0 41 P42858,P28482,P55795,O75503,Q6DKK2,Q5JRX3 6 +Hypoplasia of teeth 0.2896045494037258 0.0851070492533581 0.9321762861492096 1.0 1.0 22 O95613,Q8IWV7,P51648,O75844 4 +Reduced systolic function 0.392518960990643 0.0844514380227038 0.9326975116893212 1.0 1.0 4 P06753,Q3LXA3 2 +Abnormality of facial soft tissue 0.3050965550228356 0.0842038910756427 0.9328943245470422 1.0 1.0 121 P28070,O75844,P11047,P12235,Q9NQ11,P34897,P30153,Q9BUK6,Q0IIM8,P07196,Q9UHX1,P51530,Q7LG56,P04062,Q9Y5P6,P31749,P35270,P42356,O60313,Q9UBM7 20 +Generalized amyotrophy 0.2866487598681964 0.0825079666666823 0.9342427834528042 1.0 1.0 28 P06753,Q9Y5P6,Q13148,P22626,Q13043,P09651,P51530,P35637 8 +Frontal cortical atrophy 0.2893854488970052 0.0808248653762577 0.9355812330488168 1.0 1.0 20 P42858,Q96PZ0,O75648 3 +Coarse facial features 0.2720568464179027 0.0807756235552762 0.935620394293037 1.0 1.0 70 P10619,P41227,P61978,O95831,P28482,Q7LGA3,Q15056,Q9Y2B2,P38159,Q96A33,Q9Y2Q5,Q9UJX6,O43909,Q06787,P06280,Q7RTS9,P54802,P08236 18 +Uveitis 0.317276253916328 0.0806312735433433 0.9357351944799406 1.0 1.0 10 P14174,P49327,P01889 3 +Nasal speech 0.2812051999207972 0.0794862402501087 0.9366458756731332 1.0 1.0 41 O75648,P42858,Q96PZ0,Q7LGA3,P21964,Q4J6C6,Q9Y487 7 +Alternating esotropia 0.4365604329524937 0.07718421028362 0.938477002540664 1.0 1.0 3 P20700,P25054 2 +Recurrent mycobacterial infections 0.3864661654135377 0.0771225828511882 0.9385260279845832 1.0 1.0 4 P57076,P15260,P42224 3 +Impaired social interactions 0.2770742175984203 0.0768951580933329 0.938706949425892 1.0 1.0 53 Q8N183,Q5XKP0,O43676,O94992,Q9Y6M9,Q96CU9,Q15067,Q9NPL8,O75306,Q9UHX1,O43909,Q06787,Q86Y39 13 +Sinus bradycardia 0.435779159631066 0.0765041853160141 0.9390179843355362 1.0 1.0 3 P0DP25 1 +Abnormality of the palm 0.3083476203587724 0.0764606550849531 0.9390526149994758 1.0 1.0 127 Q8NCH0,Q06136,Q9Y487,Q14739,Q7RTS9,P61978,Q9Y619,Q8IWV7,P98175,Q9UHX1,O43909,O95721,O96028,Q6DKJ4,P31749,P07858,Q15555,O95831,P09493,P28482 20 +Abnormal protein glycosylation 0.2941141216536206 0.0762329520611262 0.939233767003642 1.0 1.0 17 Q8N511,Q9BT22,Q10471,Q9Y487,O75340 5 +Loss of speech 0.288205207130238 0.0756641709665806 0.9396862816736198 1.0 1.0 21 P50897,P07602,O15118 3 +Sea blue histiocytosis 0.4347080552853091 0.0755815358464281 0.9397520266992708 1.0 1.0 3 O15118 1 +Noncompaction cardiomyopathy 0.4332531569452655 0.0743460561927163 0.9407350308631116 1.0 1.0 3 Q15233,P21912 2 +Abnormal circulating albumin concentration 0.285115415958305 0.0738392730760075 0.941138276908299 1.0 1.0 34 Q9UJS0,Q5XKP0,Q9NPF4,Q12769,P15260,Q9BT22,Q0IIM8,Q13043,O43707,Q6PGP7,Q96AX1,P57740,Q3LXA3,O95470,Q8N1F7,Q9NSD9 16 +Genetic anticipation 0.4302465423932624 0.0718571369722158 0.9427156015664192 1.0 1.0 3 Q9UBB4,Q99700 2 +Mask like facies 0.2990289258449172 0.0716002392265565 0.9429200496904702 1.0 1.0 14 Q9NQ11,P04062 2 +Abnormal circulating igg level 0.2951057600047057 0.070268211289948 0.943980183660512 1.0 1.0 16 O43909,P49327,P17812 3 +Prenatal movement abnormality 0.2749793581614381 0.0692494349756284 0.9447910740999724 1.0 1.0 63 Q9Y5P6,O75844,Q9UBM7,Q4J6C6,Q70HW3,P51530,P51114,P04062 8 +Axonal degeneration 0.3279639630063755 0.0690358277031098 0.9449611011339164 1.0 1.0 7 Q6DKK2 1 +Abnormality of the diaphragm 0.2842721930437262 0.0678916239064776 0.9458719065240276 1.0 1.0 28 P62857,O96028,P53701,Q9UBM7,O15111 5 +Broad based gait 0.2841189876177868 0.0663310731080478 0.9471142449295992 1.0 1.0 25 O00571,P50542,P42858,P98175,Q03164,Q9Y2B2,O14773,P04062 8 +Abnormal vagina morphology 0.2857740074917293 0.0645626417744196 0.9485222301678408 1.0 1.0 22 Q8IWV7,Q9UBM7,P30153,O60566,Q15645 5 +Neoplasm of the male external genitalia 0.3123323079190971 0.0640871410315652 0.948900840767886 1.0 1.0 11 P31749 1 +Cataplexy 0.3742878329447473 0.0637251095358494 0.9491891108593586 1.0 1.0 4 O15118 1 +Bilateral external ear deformity 0.3741353383458682 0.0635685207019881 0.949313797867862 1.0 1.0 4 P14923,O94905,Q08AM6 3 +Persistent ebv viremia 0.4182200841852106 0.0627421657104206 0.949971820136322 1.0 1.0 3 O95394,Q05655 2 +Esodeviation 0.2789315240439151 0.062023287468248 0.9505442869828212 1.0 1.0 41 Q5KU26,Q9NSE4,O94992,Q9Y2B2,O43924,Q9UHX1,O75340,Q7LG56,P04062 9 +T lymphocytopenia 0.311494761701849 0.0617918691826452 0.950728578567799 1.0 1.0 10 O43909,P49327 2 +Abnormality of the tongue 0.2825795712580913 0.0617475381763792 0.950763882178578 1.0 1.0 93 O75844,Q9NQ11,O60828,O75648,P61978,P98175,Q15056,Q7LGA3,P07196,Q13510,O15111,P51114,Q9Y5P6,Q6NUK1,Q6DKJ4,P31749,P49327,P42356,O95831,Q9UBM7,Q99575,Q96A33,O43924,P67870,P28482,O15460 26 +Oral pharyngeal dysphagia 0.3115008789414881 0.0613247765690356 0.951100559084644 1.0 1.0 11 P42858,Q13510,Q01105 3 +Abnormal posterior segment imaging 0.3354144100625352 0.0611667143151232 0.9512264382061284 1.0 1.0 5 Q96S66 1 +Acquired abnormal hair pattern 0.3245417161404891 0.0609355317872792 0.9514105517378686 1.0 1.0 7 O60828,O75844 2 +Inguinal hernia 0.2718284047711191 0.060723210374919 0.951579646581409 1.0 1.0 80 Q6PJG6,Q32P28,Q15555,Q6DKJ4,Q8NCH0,Q6PGP7,P30153,Q9Y487,Q9NWM8,Q9UJX6,P28482,Q9UHX1 12 +Stomach cancer 0.3020264609136952 0.0600794922514923 0.9520923232661314 1.0 1.0 13 Q15645,O60566,P42771,O43683 4 +Short femur 0.3345350373030644 0.0598407071617989 0.952282504024418 1.0 1.0 5 Q9UHX1 1 +Angiokeratoma 0.4139321527049551 0.0598055684842351 0.9523104905087748 1.0 1.0 3 P06280 1 +Abnormal tendon morphology 0.3491686058722904 0.0593376072683422 0.9526832076031256 1.0 1.0 227 P50897,P28070,O75844,P37268,Q9NSE4,Q15392,Q9NR77,Q8NCH0,Q96AY3,Q9UJX6,Q7RTS9,Q8IZA0,Q9Y619,P07196,P41440,O43909,P51530,P04062,Q99720,Q9Y5P6,Q15041,P48449,Q6DKJ4,P23786,P42892,P42356,Q8N2K0,O60313,O95831,Q86XL3,O95140,P35637 32 +Localized osteoporosis 0.3681995792004783 0.0588496044608449 0.9530718982477682 1.0 1.0 2 P57740 1 +Neurogenic bladder 0.3236034281407012 0.0587529132221143 0.9531489134357348 1.0 1.0 7 Q9NQ11,Q04446 2 +Central diabetes insipidus 0.3669972948602298 0.0584908302905556 0.9533576663593386 1.0 1.0 2 O76024 1 +Retinal fold 0.3669972948602266 0.0584908302905545 0.9533576663593396 1.0 1.0 2 P52732 1 +Ventricular fibrillation 0.3308798258525029 0.0582414665186393 0.9535562912556584 1.0 1.0 6 P46976 1 +Abnormal renal echogenicity 0.3621881574992476 0.0571365729257096 0.9544364030148448 1.0 1.0 2 Q15058 1 +Renal salt wasting 0.3621881574992384 0.0571365729257074 0.9544364030148464 1.0 1.0 2 Q13423 1 +Glomerular sclerosis 0.2828090427582832 0.0563714216752898 0.9550459229417152 1.0 1.0 33 Q02978,O95470,Q14108 3 +Prominent nose 0.2837511621252606 0.0561883419831287 0.9551917682412554 1.0 1.0 23 Q08J23,O95613,Q02224,Q9UJX6,O43909 5 +Allergic rhinitis 0.3567778779681311 0.055759882100182 0.9555330946400572 1.0 1.0 2 O95394 1 +Multiple gastric polyps 0.3537721671175202 0.0550582020117341 0.956092095567144 1.0 1.0 2 P25054 1 +Abnormality of the hypothalamus pituitary axis 0.2670703301098868 0.054928676814057 0.956195285566856 1.0 1.0 73 Q9BUK6,Q9NSE4,O75874,Q4J6C6,O15360,P31749,P48735,Q9UHX1,P42356,Q7LG56 10 +Long upper lip 0.3636090225563954 0.0534063380417021 0.9574081553947182 1.0 1.0 4 Q8IYB7,Q9Y2D4,Q9BZK7 3 +Recurrent staphylococcus aureus infections 0.336940186354065 0.0518649739151921 0.9586362834615916 1.0 1.0 2 O95394 1 +Recurrent staphylococcal infections 0.336940186354065 0.0518649739151921 0.9586362834615916 1.0 1.0 2 O95394 1 +Abnormal lung development 0.2741052618847269 0.0508409481668103 0.959452261132626 1.0 1.0 53 O96028,Q6NUK1,O75844,P98175,Q9UBM7,O43683,P21964,P31749,O60566,Q16134,Q9UHX1,Q14739,P35453,Q15645,O15111 15 +Abnormal qt interval 0.3073701484013675 0.0487979928158733 0.9610802817716032 1.0 1.0 10 Q16836,Q9Y5P6,P0DP25 3 +Large fleshy ears 0.3950691521347024 0.0486966193072445 0.9611610700833044 1.0 1.0 3 P21281,Q9BZK7 2 +Memory impairment 0.2787739413898752 0.0485026487760411 0.9613156535101351 1.0 1.0 39 P42858,P07602,P31749,Q9NZ08,P49327,Q7LG56 6 +Abnormal urine magnesium concentration 0.3053802224225972 0.0484318478106124 0.9613720781955086 1.0 1.0 2 P05023 1 +Abnormal thyroid hormone level 0.293056807935067 0.0477053665448181 0.961951057090238 1.0 1.0 2 O14654 1 +Food allergy 0.3569924812030108 0.0476532300395306 0.9619926087459928 1.0 1.0 4 Q01082,O95394,Q9Y5S9 3 +Odontogenic neoplasm 0.272918545235937 0.0469750662260154 0.9625330998540088 1.0 1.0 2 P25054 1 +Increased level of l fucose in urine 0.2681094078749515 0.046861516811703 0.9626235995140588 1.0 1.0 2 P25054 1 +Abnormal aortic valve physiology 0.275979207088683 0.0467954927803682 0.962676221340216 1.0 1.0 42 Q6ZXV5,Q15125,O75844,P28482,Q15056,Q6PGP7,O60566,Q9NZ08,Q9UHX1,P49327,Q15645,P04062 12 +Preaxial polydactyly 0.2893487626253954 0.045273926173967 0.9638889700206352 1.0 1.0 16 O43909,O43924,Q9UHX1 3 +Respiratory insufficiency 0.3375299305140754 0.0449737747744457 0.9641282124950878 1.0 1.0 190 P53701,P11047,P12235,Q96CU9,Q9NR77,Q15067,P07602,Q9NPL8,Q96AY3,Q14739,Q70HW3,Q7RTS9,Q8NFF5,O43676,O75648,Q9Y619,O43772,Q92734,Q13510,Q7LG56,Q9Y5P6,Q08J23,Q06210,P23786,Q9Y6M9,P09651,Q15165,Q5XKP0,Q92804,O95831,O75306,Q86Y39,O95140,P35637 34 +Adenocarcinoma of the small intestine 0.3851473241130503 0.0439415492992542 0.9649509957177926 1.0 1.0 3 P25054,P43246 2 +Night sweats 0.3839434977639679 0.043411475672947 0.9653735300618728 1.0 1.0 3 P15260 1 +Ectopic anus 0.2840132198140161 0.0412831631675394 0.9670701554730176 1.0 1.0 18 P48651,P53701,Q6NUK1,Q6DKJ4,Q8IWV7,Q9Y2B2 6 +Hepatic necrosis 0.3041266670196936 0.0408312600927008 0.9674304181818918 1.0 1.0 9 Q16836 1 +Horizontal eyebrow 0.3212348952928064 0.0406993063104294 0.9675356146229452 1.0 1.0 6 P11233 1 +Delayed fine motor development 0.3046048632476357 0.0402990777747878 0.9678546890124292 1.0 1.0 10 O94992,Q9UJX6 2 +Acne 0.2897259534624414 0.0397251020003021 0.9683122889669512 1.0 1.0 15 P01889,P49327,Q9NZ08,P21964 4 +Gingival recession 0.3740228502706014 0.0394047853439044 0.968567664721667 1.0 1.0 3 P53634,Q08AM6 2 +Tapered distal phalanges of finger 0.3740228502706014 0.0394047853439044 0.968567664721667 1.0 1.0 3 P53634,Q01082 2 +3 4 finger syndactyly 0.3740228502705863 0.0394047853438988 0.9685676647216714 1.0 1.0 3 P14923,P35453 2 +Abnormality of the mitochondrion 0.2882241401992631 0.0392067223600814 0.968725574090712 1.0 1.0 103 Q8N183,Q9Y2R0,Q9UBX3,Q16836,P12235,Q96CU9,Q9NPL8,Q16134,P00846,Q70HW3,O43676,O75648,O43772,Q4J6C6,P51530,O75880,Q7LG56,P23786,Q9Y6M9,Q7KZN9,P20674,O75306,Q86Y39,P35637 24 +Abnormality of malar bones 0.2704182608452683 0.0380979817250448 0.9696095604936468 1.0 1.0 66 Q15125,Q9Y4W2,O95831,O60566,Q9Y487,P28482,Q14739,Q9HC07 8 +Abnormal talus morphology 0.2808084232111358 0.0378616619238038 0.9697979804702266 1.0 1.0 20 P98175,O75844 2 +Craniofacial asymmetry 0.364909204630041 0.0362552062655473 0.971078866659745 1.0 1.0 3 O96028 1 +Widow s peak 0.3413533834586505 0.0358857666868935 0.971373445096626 1.0 1.0 4 P21281,P29372,O15344 3 +Agammaglobulinemia 0.3628983764281461 0.0356238112101026 0.9715823217694136 1.0 1.0 3 O60220,O14920 2 +Abnormal bleeding 0.2922338955425394 0.0346359881799335 0.9723700042886176 1.0 1.0 109 O75844,Q8NCH0,O15360,Q9Y487,Q14739,Q14108,Q86YV9,Q9NWM8,Q9UHX1,P04062,P23786,P31749,Q13126,Q9NZ08,P49257,P49327,P38435,Q02978,P28482,O15460 20 +Status epilepticus with prominent motor symptoms 0.3580356966929862 0.0341862715699158 0.972728613843178 1.0 1.0 3 Q13510 1 +Aortic aneurysm 0.2724590399973478 0.0339809484148607 0.9728923428892596 1.0 1.0 56 P06753,Q6ZXV5,O75648,O75844,P61978,P42858,Q96PZ0,Q6NUK1,Q7LGA3,Q15056,Q9UJX6,P28482,Q06787,O15460 14 +Prematurely aged appearance 0.2742194691159457 0.0333146744710804 0.973423651719954 1.0 1.0 42 Q6NUK1,O75844,O95613,Q15056,Q02224,Q9BUR4,Q13126,Q9Y487,P49327,P41227 10 +Chronic hepatic failure 0.3372932743296297 0.0332279380126627 0.973492819106915 1.0 1.0 4 Q13043,P40939 2 +Aplasia hypoplasia involving the nose 0.2792754097875606 0.0330863727935197 0.9736057097366552 1.0 1.0 33 P61978,O75844,Q08J23,Q8IWV7,O95613,P55795,O94992,P28482 8 +Abnormal tracheobronchial morphology 0.2709294497920841 0.0305054282623177 0.9756639642700436 1.0 1.0 63 Q15125,P30154,Q03518,O43909,Q14739 5 +Abnormality of the intervertebral disk 0.3015697428097984 0.0295368124075116 0.97643645968474 1.0 1.0 11 O43909 1 +Abnormal macular morphology 0.2771823840298764 0.0284519382347947 0.9773017002261768 1.0 1.0 27 P50897,Q86YV9,P51648,P04062 4 +Decreased circulating copper concentration 0.3295249549007768 0.0279604561124411 0.9776936902569632 1.0 1.0 3 Q10567,Q15904 2 +Respiratory failure requiring assisted ventilation 0.3092829146869194 0.0275065117638322 0.9780557461773424 1.0 1.0 7 O75648 1 +Ectopia pupillae 0.3267820034767379 0.0270521057184113 0.9784181748645212 1.0 1.0 4 O96028 1 +Irregular femoral epiphysis 0.32020444978954 0.0265969570580937 0.9787812003183504 1.0 1.0 3 Q9NUQ7,P50542 2 +Abnormality of mouth size 0.3031067769447977 0.0253694973966111 0.9797602408251508 1.0 1.0 126 O75844,Q9NSE4,Q96PZ0,P55795,Q15392,Q01105,Q8NCH0,Q9Y487,O75648,Q9Y619,P42858,Q7LGA3,P21964,O43909,P04062,Q08J23,Q6DKJ4,P31749,Q15555,Q9UBM7,Q6PGP7,P28482 22 +Hepatic encephalopathy 0.322706766917297 0.0249174107601568 0.9801208397673216 1.0 1.0 4 Q9UJS0,Q6NUQ1,P09622 3 +Brushfield spots 0.283523752254965 0.0233930650202007 0.9813367368060468 1.0 1.0 3 P40855,P50542 2 +Abnormal response to endocrine stimulation test 0.2720986169573129 0.0228849308294638 0.981742060704879 1.0 1.0 3 Q13423,P16435 2 +Choriocarcinoma 0.2681900180396938 0.0227470680682857 0.9818520306462032 1.0 1.0 3 O96017,P42771 2 +Abnormal macroscopic urine appearance 0.2777325654735172 0.0225154718015654 0.9820367704157996 1.0 1.0 21 P23786 1 +Renal steatosis 0.2543595911004277 0.0223755096401719 0.982148415936329 1.0 1.0 3 Q5SW96,Q16822 2 +Vaginal atresia 0.2456404088995858 0.0222154141680761 0.9822761218971614 1.0 1.0 3 P16435,Q15058 2 +Recurrent sinopulmonary infections 0.298629599117675 0.0206878246627639 0.9834946814545038 1.0 1.0 8 Q9Y487 1 +Scleral staphyloma 0.3105018049738263 0.0193233197428279 0.984583180935818 1.0 1.0 4 P36404,Q969N2 2 +Aplasia of the uterus 0.2977853895158636 0.018641166841233 0.9851273621435266 1.0 1.0 8 P30153 1 +Eclabion 0.2762425795086832 0.0184588645523725 0.9852727933011988 1.0 1.0 36 Q96PZ0 1 +Functional intestinal obstruction 0.308050575443777 0.0183354354487633 0.985371258812771 1.0 1.0 4 P42771 1 +Peritoneal abscess 0.308050575443777 0.0183354354487633 0.985371258812771 1.0 1.0 4 P42771 1 +Ovarian carcinoma 0.308050575443777 0.0183354354487633 0.985371258812771 1.0 1.0 4 P42771 1 +Extrahepatic cholestasis 0.308050575443777 0.0183354354487633 0.985371258812771 1.0 1.0 4 P42771 1 +Abnormality of the menstrual cycle 0.2696633548428261 0.0167181509887336 0.9866614667895316 1.0 1.0 51 P49257,P31749,Q16740,O75844 4 +Dilated fourth ventricle 0.268781515676269 0.016676935521847 0.9866943473902184 1.0 1.0 45 Q9Y5P6,Q15125,O43505,P23786,Q9UBM7,Q9Y487 6 +Abnormal soft palate morphology 0.2632617028081377 0.014656794997288 0.9883059882501064 1.0 1.0 73 P62857,P61978,Q9Y619,Q6DKJ4,O43505,Q15392,Q9Y2B2,O15360,P34897,Q6PGP7,Q9NWM8 11 +Renal tubular atrophy 0.2968421052631618 0.0143438132912297 0.9885556852682847 1.0 1.0 4 Q96AX1,P57740,Q9NQH7 3 +Thickened ribs 0.2953326941846501 0.0138683261500868 0.9889350313702404 1.0 1.0 4 P15586,P54802 2 +Primary gonadal insufficiency 0.2943327639759912 0.0132852189073712 0.9894002407521972 1.0 1.0 9 Q13144,O76024,Q9NR50,P49770 4 +Neoplasm of the oral cavity 0.2886702461627803 0.0119272494474808 0.9904836574448844 1.0 1.0 13 P49327,P31749 2 +Choanal stenosis 0.2936221419976008 0.0107735972711529 0.991404079362016 1.0 1.0 5 O94761,P48651,P16435,Q9H9Y6 4 +Syncope 0.2922542258704199 0.0105980551756183 0.9915441336932224 1.0 1.0 12 P31749,P0DP25,Q99996 3 +Round face 0.2750254186692312 0.0103768077822533 0.991720653864486 1.0 1.0 23 Q32P28,Q03164,Q9Y2B2,Q02224,P31749,O75718 6 +Rib segmentation abnormalities 0.2910720489388313 0.0084872556470127 0.9932282310548052 1.0 1.0 5 O96028 1 +Abnormality of abdominal situs 0.2910720489388313 0.0084872556470127 0.9932282310548052 1.0 1.0 5 O96028 1 +Aplasia hypoplasia of the pubic bone 0.2910720489388313 0.0084872556470127 0.9932282310548052 1.0 1.0 5 O96028 1 +Hypoplastic pubic rami 0.2910720489388313 0.0084872556470127 0.9932282310548052 1.0 1.0 5 O96028 1 +Underdeveloped nasal alae 0.2742364231508095 0.0082279837721959 0.993435092855438 1.0 1.0 28 P61978,Q08J23,O95613,Q8IWV7,O94992,P55795,P28482 7 +Bicornuate uterus 0.29222662605612 0.0076480811440156 0.993897773625216 1.0 1.0 9 Q9UBM7 1 +Abnormality of dental structure 0.2651281369547884 0.0072046258679997 0.9942515899837074 1.0 1.0 78 P53701,O75844,Q15555,O95613,Q8IWV7,P04080,Q9UBM7,Q15056,P51648,Q02224,P21964,P31749,Q86W42,Q96AY3,Q9Y487,Q9HC07 16 +Increased nuchal translucency 0.2738330834362283 0.0064588890699852 0.9948465879621732 1.0 1.0 19 P61978,Q9UBM7,Q15056,O60566,Q15645 5 +Flushing 0.2901662617716005 0.0040319102427973 0.9967830097827912 1.0 1.0 12 Q02978 1 +Abnormal atrioventricular valve morphology 0.2726131828975812 0.0038830745431729 0.9969017625595666 1.0 1.0 39 P53701,O75844,Q6DKJ4,P55795,O43909,P28482,Q06787,P04062 8 +Abnormal circulating nitrogen compound concentration 0.2680312928116682 0.0030348759271914 0.9975785230708998 1.0 1.0 51 Q16836,O43772,P23786,Q9Y619 4 +Bilateral cleft lip 0.2234586466165454 0.0028562128126496 0.99772107499298 1.0 1.0 4 O15111,Q9NXE4,O60716 3 +Decreased circulating total igm 0.2920520839586285 0.0012318924038035 0.9990170923190382 1.0 1.0 11 O43909,P49327,Q9Y2Q5,Q13724 4 +Muscle weakness 0.3462459771183335 0.0010013042369613 0.9992010749421638 1.0 1.0 308 Q5TAQ9,P11047,P12235,Q96CU9,Q9NR77,Q15067,Q8NCH0,P07602,Q9NPL8,Q9NQ11,P34897,Q16134,P00846,Q14739,Q70HW3,Q7RTS9,Q8NFF5,Q06787,O43676,Q9BUK6,P17900,O75648,P61978,P42858,P00374,O43505,O43772,Q4J6C6,P07196,Q9NWM8,Q92734,P41440,O43909,Q6DKK2,Q9UHX1,O95721,P51530,Q7LG56,P51114,Q13510,Q99720,Q9Y5P6,Q8NI60,P22626,Q06210,P23786,O94992,Q9Y6M9,O14979,P31749,Q13126,Q96TA2,P35270,P09651,Q9HC07,P42356,O15270,O60313,Q15165,Q5XKP0,Q92804,O95831,Q5T8D3,O75306,Q86Y39,Q15120,O95140,O15460,P35637 69 diff --git a/msigdb_hp/selections.json b/msigdb_hp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..f0cc3e609204c1158144fe94429001c7549407ad --- /dev/null +++ b/msigdb_hp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["11 pairs of ribs", "2 3 finger syndactyly", "2 3 toe cutaneous syndactyly", "2 3 toe syndactyly", "3 4 finger syndactyly", "3 methylglutaconic aciduria", "4 5 toe syndactyly", "Abdominal aortic aneurysm", "Abdominal distention", "Abdominal obesity", "Abdominal pain", "Abdominal wall muscle weakness", "Abducens palsy", "Abnormal 2nd finger morphology", "Abnormal 3rd finger morphology", "Abnormal 5th finger morphology", "Abnormal 5th finger phalanx morphology", "Abnormal abdomen morphology", "Abnormal acetabulum morphology", "Abnormal activity of mitochondrial respiratory chain", "Abnormal adipose tissue morphology", "Abnormal aggressive impulsive or violent behavior", "Abnormal aldolase level", "Abnormal anatomic location of the heart", "Abnormal anterior chamber morphology", "Abnormal anterior eye segment morphology", "Abnormal anterior horn cell morphology", "Abnormal aortic arch morphology", "Abnormal aortic morphology", "Abnormal aortic valve cusp morphology", "Abnormal aortic valve morphology", "Abnormal aortic valve physiology", "Abnormal arachnoid mater morphology", "Abnormal arm span", "Abnormal arterial physiology", "Abnormal astrocyte morphology", "Abnormal atrial arrangement", "Abnormal atrioventricular conduction", "Abnormal atrioventricular valve morphology", "Abnormal atrioventricular valve physiology", "Abnormal auditory evoked potentials", "Abnormal autonomic nervous system physiology", "Abnormal b cell morphology", "Abnormal b cell subset distribution", "Abnormal basal ganglia mri signal intensity", "Abnormal basophil count", "Abnormal basophil morphology", "Abnormal biliary tract morphology", "Abnormal bleeding", "Abnormal blistering of the skin", "Abnormal blood carbon dioxide level", "Abnormal blood chloride concentration", "Abnormal blood gas level", "Abnormal blood glucose concentration", "Abnormal blood inorganic cation concentration", "Abnormal blood ion concentration", "Abnormal blood monovalent inorganic cation concentration", "Abnormal blood phosphate concentration", "Abnormal blood potassium concentration", "Abnormal blood sodium concentration", "Abnormal blood transition element cation concentration", "Abnormal blood zinc concentration", "Abnormal bone structure", "Abnormal bowel sounds", "Abnormal brain choline level by mrs", "Abnormal brain lactate level by mrs", "Abnormal brain n acetyl aspartate level by mrs", "Abnormal brain positron emission tomography", "Abnormal brainstem morphology", "Abnormal brainstem mri signal intensity", "Abnormal branching pattern of the aortic arch", "Abnormal breath sound", "Abnormal bronchoalveolar lavage fluid morphology", "Abnormal bronchus morphology", "Abnormal bronchus physiology", "Abnormal c peptide level", "Abnormal c reactive protein level", "Abnormal calcification of the carpal bones", "Abnormal calcium phosphate regulating hormone level", "Abnormal cardiac atrium morphology", "Abnormal cardiac exercise stress test", "Abnormal cardiac septum morphology", "Abnormal cardiac test", "Abnormal cardiac ventricle morphology", "Abnormal cardiac ventricular function", "Abnormal cardiomyocyte morphology", "Abnormal carotid artery morphology", "Abnormal cartilage morphology", "Abnormal caudate nucleus morphology", "Abnormal cd4 cd8 ratio", "Abnormal cell morphology", "Abnormal cell proliferation", "Abnormal cellular composition of bronchoalveolar fluid", "Abnormal cellular phenotype", "Abnormal central sensory function", "Abnormal cerebellar vermis morphology", "Abnormal cerebral artery morphology", "Abnormal cerebral cortex morphology", "Abnormal cerebral vascular morphology", "Abnormal cerebral vein morphology", "Abnormal cerebral ventricle morphology", "Abnormal cerebrospinal fluid metabolite concentration", "Abnormal cervical curvature", "Abnormal cervical spine morphology", "Abnormal chorioretinal morphology", "Abnormal choroid morphology", "Abnormal choroid plexus morphology", "Abnormal chromosome morphology", "Abnormal ciliary body morphology", "Abnormal circulating acetylcarnitine concentration", "Abnormal circulating albumin concentration", "Abnormal circulating amino acid concentration", "Abnormal circulating amylase level", "Abnormal circulating androgen level", "Abnormal circulating apolipoprotein concentration", "Abnormal circulating arginine concentration", "Abnormal circulating aromatic amino acid concentration", "Abnormal circulating aspartate family amino acid concentration", "Abnormal circulating bilirubin concentration", "Abnormal circulating branched chain amino acid concentration", "Abnormal circulating carbohydrate concentration", "Abnormal circulating carboxylic acid concentration", "Abnormal circulating ceruloplasmin concentration", "Abnormal circulating cholesterol concentration", "Abnormal circulating citrulline concentration", "Abnormal circulating copper concentration", "Abnormal circulating creatinine concentration", "Abnormal circulating dehydroepiandrosterone concentration", "Abnormal circulating dicarboxylic acid concentration", "Abnormal circulating estrogen level", "Abnormal circulating fatty acid anion concentration", "Abnormal circulating fatty acid concentration", "Abnormal circulating ferritin concentration", "Abnormal circulating follicle stimulating hormone concentration", "Abnormal circulating free fatty acid concentration", "Abnormal circulating gaba concentration", "Abnormal circulating glutamine concentration", "Abnormal circulating glutamine family amino acid concentration", "Abnormal circulating glycine concentration", "Abnormal circulating gonadotropin concentration", "Abnormal circulating hormone concentration", "Abnormal circulating iga level", "Abnormal circulating ige level", "Abnormal circulating igg level", "Abnormal circulating igm level", "Abnormal circulating inhibin level", "Abnormal circulating lipid concentration", "Abnormal circulating long chain fatty acid concentration", "Abnormal circulating metabolite concentration", "Abnormal circulating methionine concentration", "Abnormal circulating monocarboxylic acid cocentration", "Abnormal circulating nitrogen compound concentration", "Abnormal circulating non proteinogenic amino acid concentration", "Abnormal circulating nucleobase concentration", "Abnormal circulating phenylalanine concentration", "Abnormal circulating porphyrin concentration", "Abnormal circulating progesterone level", "Abnormal circulating proline concentration", "Abnormal circulating protein concentration", "Abnormal circulating proteinogenic amino acid concentration", "Abnormal circulating proteinogenic amino acid derivative concentration", "Abnormal circulating pyruvate family amino acid concentration", "Abnormal circulating renin", "Abnormal circulating serine concentration", "Abnormal circulating serine family amino acid concentration", "Abnormal circulating sex hormone concentration", "Abnormal circulating sulfur amino acid concentration", "Abnormal circulating tyrosine concentration", "Abnormal clavicle morphology", "Abnormal cns myelination", "Abnormal coccyx morphology", "Abnormal cochlea morphology", "Abnormal conjugate eye movement", "Abnormal conjunctiva morphology", "Abnormal connection of the cardiac segments", "Abnormal consumption behavior", "Abnormal conus terminalis morphology", "Abnormal cornea morphology", "Abnormal corneal epithelium morphology", "Abnormal coronary artery morphology", "Abnormal coronary sinus morphology", "Abnormal corpus callosum morphology", "Abnormal corpus striatum morphology", "Abnormal cortical bone morphology", "Abnormal cortical gyration", "Abnormal cranial nerve morphology", "Abnormal cranial nerve physiology", "Abnormal cry", "Abnormal csf carboxylic acid concentration", "Abnormal csf metabolite level", "Abnormal csf protein level", "Abnormal csf pyruvate family amino acid concentration", "Abnormal cutaneous elastic fiber morphology", "Abnormal delayed hypersensitivity skin test", "Abnormal delivery", "Abnormal dense granules", "Abnormal dental pulp morphology", "Abnormal dental root morphology", "Abnormal dentate nucleus morphology", "Abnormal dentin morphology", "Abnormal dermatoglyphics", "Abnormal dermoepidermal junction morphology", "Abnormal diaphysis morphology", "Abnormal distal phalanx morphology of finger", "Abnormal dlco", "Abnormal drinking behavior", "Abnormal duodenum morphology", "Abnormal dura mater morphology", "Abnormal eating behavior", "Abnormal echocardiogram", "Abnormal elasticity of skin", "Abnormal electrophysiology of sinoatrial node origin", "Abnormal electroretinogram", "Abnormal emotion affect behavior", "Abnormal enchondral ossification", "Abnormal endocardium morphology", "Abnormal endocrine physiology", "Abnormal enzyme coenzyme activity", "Abnormal eosinophil morphology", "Abnormal epidermal morphology", "Abnormal epiglottis morphology", "Abnormal epiphyseal ossification", "Abnormal epiphysis morphology of the phalanges of the hand", "Abnormal erythrocyte enzyme level", "Abnormal erythrocyte morphology", "Abnormal erythrocyte physiology", "Abnormal erythrocyte sedimentation rate", "Abnormal esophagus morphology", "Abnormal esophagus physiology", "Abnormal external genitalia", "Abnormal exteroceptive sensation", "Abnormal eyebrow morphology", "Abnormal eyelash morphology", "Abnormal eyelid morphology", "Abnormal eyelid physiology", "Abnormal facial expression", "Abnormal facial shape", "Abnormal factor ix activity", "Abnormal fallopian tube morphology", "Abnormal fear anxiety related behavior", "Abnormal female reproductive system physiology", "Abnormal femoral head morphology", "Abnormal femoral neck head morphology", "Abnormal femoral neck morphology", "Abnormal finger flexion creases", "Abnormal finger phalanx morphology", "Abnormal fingernail morphology", "Abnormal fingertip morphology", "Abnormal foot bone ossification", "Abnormal foramen magnum morphology", "Abnormal forearm bone morphology", "Abnormal form of the vertebral bodies", "Abnormal foveal morphology", "Abnormal full field electroretinogram", "Abnormal fundus autofluorescence imaging", "Abnormal gallbladder morphology", "Abnormal gastrointestinal motility", "Abnormal glial cell morphology", "Abnormal globus pallidus morphology", "Abnormal glomerular basement membrane morphology", "Abnormal glomerular filtration rate", "Abnormal glomerular mesangial cellularity", "Abnormal glomerular mesangium morphology", "Abnormal glucose homeostasis", "Abnormal glycosylation", "Abnormal granulocyte count", "Abnormal granulocytopoietic cell morphology", "Abnormal greater sciatic notch morphology", "Abnormal growth hormone level", "Abnormal hair laboratory examination", "Abnormal hair morphology", "Abnormal hair pattern", "Abnormal hair quantity", "Abnormal hair whorl", "Abnormal hand bone ossification", "Abnormal hand morphology", "Abnormal hdl cholesterol concentration", "Abnormal head movements", "Abnormal heart rate variability", "Abnormal heart sound", "Abnormal heart valve morphology", "Abnormal heart valve physiology", "Abnormal hemidiaphragm morphology", "Abnormal hemoglobin", "Abnormal hemoglobin concentration", "Abnormal hepatic iron concentration", "Abnormal humerus morphology", "Abnormal hypothalamus morphology", "Abnormal hypothalamus physiology", "Abnormal ileum morphology", "Abnormal iliac wing morphology", "Abnormal ilium morphology", "Abnormal immune system morphology", "Abnormal incisor morphology", "Abnormal inflammatory response", "Abnormal insulin level", "Abnormal internal carotid artery morphology", "Abnormal internal genitalia", "Abnormal intestine morphology", "Abnormal intraocular pressure", "Abnormal involuntary eye movements", "Abnormal iris pigmentation", "Abnormal jaw morphology", "Abnormal jejunum morphology", "Abnormal joint morphology", "Abnormal labia majora morphology", "Abnormal labia minora morphology", "Abnormal labia morphology", "Abnormal lacrimal duct morphology", "Abnormal lacrimal gland morphology", "Abnormal lacrimal punctum morphology", "Abnormal lactate dehydrogenase level", "Abnormal large intestine morphology", "Abnormal large intestine physiology", "Abnormal larynx morphology", "Abnormal larynx physiology", "Abnormal lateral ventricle morphology", "Abnormal ldl cholesterol concentration", "Abnormal left atrium morphology", "Abnormal left ventricle morphology", "Abnormal left ventricular outflow tract morphology", "Abnormal length of corpus callosum", "Abnormal leukocyte count", "Abnormal leukocyte physiology", "Abnormal levels of alpha fetoprotein", "Abnormal libido", "Abnormal light and dark adapted electroretinogram", "Abnormal lip morphology", "Abnormal liver morphology", "Abnormal liver parenchyma morphology", "Abnormal liver physiology", "Abnormal localization of kidney", "Abnormal location of ears", "Abnormal lower limb bone morphology", "Abnormal lower motor neuron morphology", "Abnormal lumbar spine morphology", "Abnormal lung development", "Abnormal lung lobation", "Abnormal lymphatic vessel morphology", "Abnormal lymphocyte morphology", "Abnormal macrophage morphology", "Abnormal macroscopic urine appearance", "Abnormal macular morphology", "Abnormal magnesium concentration", "Abnormal male reproductive system physiology", "Abnormal mandibular ramus morphology", "Abnormal mast cell morphology", "Abnormal mean corpuscular hemoglobin concentration", "Abnormal mean corpuscular volume", "Abnormal megakaryocyte morphology", "Abnormal meningeal morphology", "Abnormal metabolic brain imaging by mrs", "Abnormal metabolism", "Abnormal metacarpal morphology", "Abnormal metaphyseal trabeculation", "Abnormal metatarsal morphology", "Abnormal midbrain morphology", "Abnormal middle phalanx morphology of the hand", "Abnormal mitochondria in muscle tissue", "Abnormal mitochondrial morphology", "Abnormal mitochondrial number", "Abnormal mitochondrial shape", "Abnormal mitral valve physiology", "Abnormal monocyte morphology", "Abnormal morphology of myocardial trabeculae", "Abnormal morphology of the abdominal musculature", "Abnormal morphology of the choroidal vasculature", "Abnormal morphology of the conjunctival vasculature", "Abnormal morphology of the great vessels", "Abnormal morphology of the limbic system", "Abnormal morphology of the musculature of the neck", "Abnormal morphology of the olfactory bulb", "Abnormal morphology of the radius", "Abnormal motor evoked potentials", "Abnormal motor nerve conduction velocity", "Abnormal muscle fiber alpha dystroglycan", "Abnormal muscle fiber morphology", "Abnormal muscle fiber protein expression", "Abnormal muscle fiber type distribution", "Abnormal muscle glycogen content", "Abnormal myelination", "Abnormal myeloid cell morphology", "Abnormal myeloid leukocyte morphology", "Abnormal myocardium morphology", "Abnormal nasal base", "Abnormal nasal bridge morphology", "Abnormal nasal mucosa morphology", "Abnormal nasolacrimal system morphology", "Abnormal natural killer cell morphology", "Abnormal natural killer cell physiology", "Abnormal nephron morphology", "Abnormal nerve conduction velocity", "Abnormal nervous system electrophysiology", "Abnormal neural tube morphology", "Abnormal neuron morphology", "Abnormal neutrophil count", "Abnormal nipple morphology", "Abnormal number of erythroid precursors", "Abnormal number of granulocyte precursors", "Abnormal number of incisors", "Abnormal number of permanent teeth", "Abnormal number of teeth", "Abnormal odontoid tissue morphology", "Abnormal optical coherence tomography", "Abnormal oral frenulum morphology", "Abnormal oral glucose tolerance", "Abnormal oral mucosa morphology", "Abnormal oral physiology", "Abnormal ossification involving the femoral head and neck", "Abnormal ovarian morphology", "Abnormal ovarian physiology", "Abnormal palate morphology", "Abnormal palmar dermatoglyphics", "Abnormal pancreas morphology", "Abnormal pancreas size", "Abnormal paranasal sinus morphology", "Abnormal parietal bone morphology", "Abnormal parotid gland morphology", "Abnormal patella morphology", "Abnormal pattern of respiration", "Abnormal pelvis bone morphology", "Abnormal pelvis bone ossification", "Abnormal penis morphology", "Abnormal pericardium morphology", "Abnormal perifollicular morphology", "Abnormal peripheral action potential amplitude", "Abnormal peripheral myelination", "Abnormal peripheral nervous system morphology", "Abnormal peripheral nervous system physiology", "Abnormal peristalsis", "Abnormal periventricular white matter morphology", "Abnormal phalangeal joint morphology of the hand", "Abnormal pharynx morphology", "Abnormal pigmentation of the oral mucosa", "Abnormal pineal morphology", "Abnormal placenta morphology", "Abnormal placental membrane morphology", "Abnormal placental size", "Abnormal platelet aggregation", "Abnormal platelet function", "Abnormal platelet granules", "Abnormal platelet morphology", "Abnormal platelet volume", "Abnormal pleura morphology", "Abnormal pons morphology", "Abnormal posterior segment imaging", "Abnormal posturing", "Abnormal pr interval", "Abnormal preputium morphology", "Abnormal prolactin level", "Abnormal proportion of cd4 positive t cells", "Abnormal proportion of cd8 positive t cells", "Abnormal proportion of class switched memory b cells", "Abnormal proportion of double negative alpha beta regulatory t cell", "Abnormal prostate morphology", "Abnormal protein glycosylation", "Abnormal protein o linked glycosylation", "Abnormal proximal phalanx morphology of the hand", "Abnormal pulmonary interstitial morphology", "Abnormal pulmonary thoracic imaging finding", "Abnormal pulmonary valve morphology", "Abnormal pulmonary valve physiology", "Abnormal pupil morphology", "Abnormal pupillary function", "Abnormal pupillary light reflex", "Abnormal pyramidal sign", "Abnormal qrs complex", "Abnormal qt interval", "Abnormal rectum morphology", "Abnormal reflex", "Abnormal renal collecting system morphology", "Abnormal renal cortex morphology", "Abnormal renal corticomedullary differentiation", "Abnormal renal echogenicity", "Abnormal renal insterstitial morphology", "Abnormal renal medulla morphology", "Abnormal renal morphology", "Abnormal renal pelvis morphology", "Abnormal renal physiology", "Abnormal renal resorption", "Abnormal renal tubule morphology", "Abnormal renal vascular morphology", "Abnormal respiratory motile cilium morphology", "Abnormal respiratory motile cilium physiology", "Abnormal respiratory system morphology", "Abnormal response to acth stimulation test", "Abnormal response to endocrine stimulation test", "Abnormal response to insulin tolerance test", "Abnormal reticulocyte morphology", "Abnormal retinal artery morphology", "Abnormal retinal morphology", "Abnormal retinal vascular morphology", "Abnormal rib cage morphology", "Abnormal rib ossification", "Abnormal right atrium morphology", "Abnormal right ventricle morphology", "Abnormal right ventricular function", "Abnormal saccadic eye movements", "Abnormal sacroiliac joint morphology", "Abnormal sacrum morphology", "Abnormal salivary gland morphology", "Abnormal sarcomere morphology", "Abnormal scalp morphology", "Abnormal scapula morphology", "Abnormal sclera morphology", "Abnormal scrotal rugation", "Abnormal sella turcica morphology", "Abnormal sensory nerve conduction velocity", "Abnormal serum insulin like growth factor 1 level", "Abnormal serum interferon level", "Abnormal serum interleukin level", "Abnormal serum iron concentration", "Abnormal sex determination", "Abnormal shape of the frontal region", "Abnormal shape of the occiput", "Abnormal shape of the palpebral fissure", "Abnormal sharpey fiber morphology", "Abnormal shoulder morphology", "Abnormal shoulder physiology", "Abnormal size of pituitary gland", "Abnormal size of the clitoris", "Abnormal size of the dental root", "Abnormal size of the palpebral fissures", "Abnormal skin morphology of the palm", "Abnormal social behavior", "Abnormal soft palate morphology", "Abnormal speech prosody", "Abnormal sperm motility", "Abnormal spermatogenesis", "Abnormal spinal meningeal morphology", "Abnormal sputum", "Abnormal st segment", "Abnormal sternal ossification", "Abnormal sternum morphology", "Abnormal stomach morphology", "Abnormal stool composition", "Abnormal subarachnoid space morphology", "Abnormal subclavian artery morphology", "Abnormal subcutaneous fat tissue distribution", "Abnormal substantia nigra morphology", "Abnormal superior cerebellar peduncle morphology", "Abnormal sweat gland morphology", "Abnormal sweat homeostasis", "Abnormal synaptic transmission at the neuromuscular junction", "Abnormal systemic arterial morphology", "Abnormal systemic blood pressure", "Abnormal t cell activation", "Abnormal t cell morphology", "Abnormal t cell proliferation", "Abnormal t cell subset distribution", "Abnormal t wave", "Abnormal talus morphology", "Abnormal tarsal ossification", "Abnormal temper tantrums", "Abnormal temporal bone morphology", "Abnormal tendon morphology", "Abnormal testis morphology", "Abnormal thalamic mri signal intensity", "Abnormal thalamic size", "Abnormal thoracic spine morphology", "Abnormal thorax morphology", "Abnormal thrombocyte morphology", "Abnormal thrombosis", "Abnormal thumb morphology", "Abnormal thyroid hormone level", "Abnormal thyroid morphology", "Abnormal thyroid stimulating hormone level", "Abnormal tissue metabolite concentration", "Abnormal toenail morphology", "Abnormal tongue morphology", "Abnormal tongue physiology", "Abnormal trabecular bone morphology", "Abnormal tracheal morphology", "Abnormal tracheobronchial morphology", "Abnormal transferrin saturation", "Abnormal tricuspid valve morphology", "Abnormal tricuspid valve physiology", "Abnormal umbilicus morphology", "Abnormal upper limb bone morphology", "Abnormal upper motor neuron morphology", "Abnormal ureter morphology", "Abnormal ureter physiology", "Abnormal urinary color", "Abnormal urinary electrolyte concentration", "Abnormal urine alpha ketoglutarate concentration", "Abnormal urine carbohydrate level", "Abnormal urine carboxylic acid level", "Abnormal urine cytology", "Abnormal urine hormone level", "Abnormal urine magnesium concentration", "Abnormal urine metabolite level", "Abnormal urine ph", "Abnormal urine phosphate concentration", "Abnormal urine potassium concentration", "Abnormal urine protein level", "Abnormal urine sodium concentration", "Abnormal uterus morphology", "Abnormal uvea morphology", "Abnormal uvula morphology", "Abnormal vagina morphology", "Abnormal vascular morphology", "Abnormal vascular physiology", "Abnormal vena cava morphology", "Abnormal venous morphology", "Abnormal ventricular septum morphology", "Abnormal vertebral morphology", "Abnormal vertebral segmentation and fusion", "Abnormal vestibulo ocular reflex", "Abnormal visual electrophysiology", "Abnormal visual field test", "Abnormal visual fixation", "Abnormal vitamin b12 level", "Abnormal vitreous humor morphology", "Abnormal waist to hip ratio", "Abnormal z disc morphology", "Abnormalities of placenta or umbilical cord", "Abnormality iris morphology", "Abnormality of abdominal situs", "Abnormality of acid base homeostasis", "Abnormality of adrenal morphology", "Abnormality of adrenal physiology", "Abnormality of alkaline phosphatase level", "Abnormality of amino acid metabolism", "Abnormality of bladder morphology", "Abnormality of blood circulation", "Abnormality of blood volume homeostasis", "Abnormality of body mass index", "Abnormality of bone marrow cell morphology", "Abnormality of bone mineral density", "Abnormality of canine", "Abnormality of cardiovascular system electrophysiology", "Abnormality of carpal bone ossification", "Abnormality of cartilage of external ear", "Abnormality of central nervous system electrophysiology", "Abnormality of chorioretinal pigmentation", "Abnormality of chromosome segregation", "Abnormality of chromosome stability", "Abnormality of circulating adrenocorticotropin level", "Abnormality of circulating enzyme level", "Abnormality of circulating fibrinogen", "Abnormality of circulating glucocorticoid level", "Abnormality of circulating leptin level", "Abnormality of coagulation", "Abnormality of complement system", "Abnormality of coordination", "Abnormality of corneal size", "Abnormality of corneal stroma", "Abnormality of corneal thickness", "Abnormality of cranial sutures", "Abnormality of cytokine secretion", "Abnormality of dental color", "Abnormality of dental eruption", "Abnormality of dental morphology", "Abnormality of dental structure", "Abnormality of dermal melanosomes", "Abnormality of digestive system morphology", "Abnormality of dna repair", "Abnormality of earlobe", "Abnormality of endocrine pancreas physiology", "Abnormality of epiphysis morphology", "Abnormality of exocrine pancreas physiology", "Abnormality of extrapyramidal motor function", "Abnormality of facial adipose tissue", "Abnormality of facial musculature", "Abnormality of facial skeleton", "Abnormality of facial soft tissue", "Abnormality of female external genitalia", "Abnormality of femur morphology", "Abnormality of fibula morphology", "Abnormality of finger", "Abnormality of fluid regulation", "Abnormality of folate metabolism", "Abnormality of fontanelles", "Abnormality of foveal pigmentation", "Abnormality of frontal sinus", "Abnormality of frontalis muscle belly", "Abnormality of fundus pigmentation", "Abnormality of globe location", "Abnormality of globe size", "Abnormality of glycolipid metabolism", "Abnormality of hair growth", "Abnormality of hair pigmentation", "Abnormality of hair texture", "Abnormality of hand joint mobility", "Abnormality of head blood vessel", "Abnormality of hepatobiliary system physiology", "Abnormality of hindbrain morphology", "Abnormality of humoral immunity", "Abnormality of immune serum protein physiology", "Abnormality of iron homeostasis", "Abnormality of krebs cycle metabolism", "Abnormality of lens shape", "Abnormality of limb epiphysis morphology", "Abnormality of lipoprotein cholesterol concentration", "Abnormality of long bone morphology", "Abnormality of lower limb epiphysis morphology", "Abnormality of lower limb joint", "Abnormality of lower limb metaphyses", "Abnormality of lower lip", "Abnormality of lysosomal metabolism", "Abnormality of macular pigmentation", "Abnormality of malar bones", "Abnormality of male internal genitalia", "Abnormality of masticatory muscle", "Abnormality of metacarpal epiphyses", "Abnormality of metacarpophalangeal joint", "Abnormality of mouth shape", "Abnormality of mouth size", "Abnormality of muscle size", "Abnormality of nail color", "Abnormality of neuronal migration", "Abnormality of neutrophil morphology", "Abnormality of neutrophil physiology", "Abnormality of neutrophils", "Abnormality of ocular smooth pursuit", "Abnormality of pain sensation", "Abnormality of pancreas physiology", "Abnormality of pelvic girdle bone morphology", "Abnormality of periauricular region", "Abnormality of peripheral nerves", "Abnormality of prenatal development or birth", "Abnormality of primary teeth", "Abnormality of prothrombin", "Abnormality of pulmonary circulation", "Abnormality of refraction", "Abnormality of renal excretion", "Abnormality of renin angiotensin system", "Abnormality of reproductive system physiology", "Abnormality of retinal pigmentation", "Abnormality of salivation", "Abnormality of secondary sexual hair", "Abnormality of skeletal maturation", "Abnormality of skeletal muscle fiber size", "Abnormality of skin adnexa physiology", "Abnormality of skin physiology", "Abnormality of skin pigmentation", "Abnormality of skull ossification", "Abnormality of small intestinal villus morphology", "Abnormality of somatosensory evoked potentials", "Abnormality of subcutaneous fat tissue", "Abnormality of t cell physiology", "Abnormality of taste sensation", "Abnormality of temperature regulation", "Abnormality of thalamus morphology", "Abnormality of the 1st metacarpal", "Abnormality of the 2nd toe", "Abnormality of the 3rd toe", "Abnormality of the 4th metacarpal", "Abnormality of the 5th metacarpal", "Abnormality of the 5th toe", "Abnormality of the abdominal organs", "Abnormality of the abdominal wall", "Abnormality of the achilles tendon", "Abnormality of the adrenal glands", "Abnormality of the alveolar ridges", "Abnormality of the amniotic fluid", "Abnormality of the ankles", "Abnormality of the anterior fontanelle", "Abnormality of the antihelix", "Abnormality of the antitragus", "Abnormality of the anus", "Abnormality of the auditory canal", "Abnormality of the autonomic nervous system", "Abnormality of the axillary hair", "Abnormality of the basal ganglia", "Abnormality of the biliary system", "Abnormality of the bladder", "Abnormality of the brainstem white matter", "Abnormality of the breast", "Abnormality of the calcaneus", "Abnormality of the calf", "Abnormality of the calf musculature", "Abnormality of the calvaria", "Abnormality of the carpal bones", "Abnormality of the cerebral subcortex", "Abnormality of the cerebrospinal fluid", "Abnormality of the cervical spine", "Abnormality of the cheek", "Abnormality of the chin", "Abnormality of the choanae", "Abnormality of the clitoris", "Abnormality of the coagulation cascade", "Abnormality of the columella", "Abnormality of the common coagulation pathway", "Abnormality of the costochondral junction", "Abnormality of the crus of the helix", "Abnormality of the curvature of the cornea", "Abnormality of the curvature of the vertebral column", "Abnormality of the dentition", "Abnormality of the diaphragm", "Abnormality of the diencephalon", "Abnormality of the distal phalanges of the toes", "Abnormality of the distal phalanx of the hallux", "Abnormality of the distal phalanx of the thumb", "Abnormality of the dorsal column of the spinal cord", "Abnormality of the elbow", "Abnormality of the endometrium", "Abnormality of the epididymis", "Abnormality of the epiphyses of the distal phalanx of finger", "Abnormality of the eustachian tube", "Abnormality of the external nose", "Abnormality of the extraocular muscles", "Abnormality of the extrinsic pathway", "Abnormality of the female genitalia", "Abnormality of the fetal cardiovascular system", "Abnormality of the fifth metatarsal bone", "Abnormality of the first metatarsal bone", "Abnormality of the fontanelles or cranial sutures", "Abnormality of the foot musculature", "Abnormality of the forearm", "Abnormality of the forehead", "Abnormality of the frontal hairline", "Abnormality of the gallbladder", "Abnormality of the gastric mucosa", "Abnormality of the gingiva", "Abnormality of the glabella", "Abnormality of the glenoid fossa", "Abnormality of the hairline", "Abnormality of the hallux", "Abnormality of the helix", "Abnormality of the hepatic vasculature", "Abnormality of the humeroradial joint", "Abnormality of the humerus", "Abnormality of the hypothalamus pituitary axis", "Abnormality of the hypothenar eminence", "Abnormality of the incisor", "Abnormality of the inner ear", "Abnormality of the internal auditory canal", "Abnormality of the intervertebral disk", "Abnormality of the intrahepatic bile duct", "Abnormality of the intrinsic pathway", "Abnormality of the ischium", "Abnormality of the kidney", "Abnormality of the knee", "Abnormality of the larynx", "Abnormality of the lens", "Abnormality of the leydig cells", "Abnormality of the liver", "Abnormality of the lower urinary tract", "Abnormality of the lymph nodes", "Abnormality of the lymphatic system", "Abnormality of the mastoid", "Abnormality of the maxilla", "Abnormality of the menstrual cycle", "Abnormality of the metacarpal bones", "Abnormality of the metaphysis", "Abnormality of the metopic suture", "Abnormality of the middle ear", "Abnormality of the middle ear ossicles", "Abnormality of the middle phalanges of the toes", "Abnormality of the middle phalanx of the 2nd finger", "Abnormality of the middle phalanx of the 5th finger", "Abnormality of the midface", "Abnormality of the mitochondrion", "Abnormality of the musculature of the hand", "Abnormality of the musculature of the limbs", "Abnormality of the musculature of the lower limbs", "Abnormality of the musculature of the thigh", "Abnormality of the musculature of the upper arm", "Abnormality of the musculature of the upper limbs", "Abnormality of the nail", "Abnormality of the nasal alae", "Abnormality of the nasal bone", "Abnormality of the nasal cavity", "Abnormality of the nasal dorsum", "Abnormality of the nasal septum", "Abnormality of the nasal skeleton", "Abnormality of the nasal tip", "Abnormality of the nasolabial region", "Abnormality of the neck", "Abnormality of the odontoid process", "Abnormality of the optic nerve", "Abnormality of the outer ear", "Abnormality of the ovary", "Abnormality of the palm", "Abnormality of the palpebral fissures", "Abnormality of the pancreas", "Abnormality of the parathyroid gland", "Abnormality of the parathyroid morphology", "Abnormality of the periorbital region", "Abnormality of the peripheral nervous system", "Abnormality of the peritoneum", "Abnormality of the periungual region", "Abnormality of the phalanges of the 2nd finger", "Abnormality of the phalanges of the hallux", "Abnormality of the phalanges of the toes", "Abnormality of the pharynx", "Abnormality of the philtrum", "Abnormality of the pineal gland", "Abnormality of the pinna", "Abnormality of the pituitary gland", "Abnormality of the plantar skin of foot", "Abnormality of the posterior pituitary", "Abnormality of the protein c anticoagulant pathway", "Abnormality of the proximal phalanx of the thumb", "Abnormality of the pubic bone", "Abnormality of the pubic hair", "Abnormality of the pulmonary artery", "Abnormality of the pulmonary vasculature", "Abnormality of the pulmonary veins", "Abnormality of the pylorus", "Abnormality of the radial head", "Abnormality of the radioulnar joints", "Abnormality of the ribs", "Abnormality of the scrotum", "Abnormality of the sense of smell", "Abnormality of the septum pellucidum", "Abnormality of the shoulder girdle musculature", "Abnormality of the skull base", "Abnormality of the small intestine", "Abnormality of the spinal cord", "Abnormality of the spinocerebellar tracts", "Abnormality of the spleen", "Abnormality of the stapes", "Abnormality of the subungual region", "Abnormality of the supraorbital ridges", "Abnormality of the synovia", "Abnormality of the tarsal bones", "Abnormality of the temporomandibular joint", "Abnormality of the testis size", "Abnormality of the thenar eminence", "Abnormality of the thoracic cavity", "Abnormality of the thymus", "Abnormality of the thyroid gland", "Abnormality of the tongue", "Abnormality of the tongue muscle", "Abnormality of the tonsils", "Abnormality of the tragus", "Abnormality of the ulna", "Abnormality of the umbilical cord", "Abnormality of the upper arm", "Abnormality of the upper respiratory tract", "Abnormality of the ureter", "Abnormality of the urethra", "Abnormality of the urinary system physiology", "Abnormality of the uterus", "Abnormality of the vasculature of the eye", "Abnormality of the vertebral endplates", "Abnormality of the vestibulocochlear nerve", "Abnormality of the voice", "Abnormality of the wrist", "Abnormality of the zygomatic bone", "Abnormality of thyroid physiology", "Abnormality of tibia morphology", "Abnormality of toe", "Abnormality of tumor necrosis factor secretion", "Abnormality of ulnar metaphysis", "Abnormality of upper limb epiphysis morphology", "Abnormality of upper limb joint", "Abnormality of upper limb metaphysis", "Abnormality of upper lip", "Abnormality of upper lip vermillion", "Abnormality of urinary uric acid concentration", "Abnormality of urine calcium concentration", "Abnormality of urine catecholamine concentration", "Abnormality of urine homeostasis", "Abnormality of visual evoked potentials", "Abnormality of vitamin a metabolism", "Abnormality of vitamin b metabolism", "Abnormality of vitamin b12 metabolism", "Abnormality of vitamin d metabolism", "Abnormality of vitamin e metabolism", "Abnormality of vitamin k metabolism", "Abnormality of vitamin metabolism", "Abnormality on pulmonary function testing", "Abnormally folded helix", "Abnormally large globe", "Abnormally lax or hyperextensible skin", "Abnormally low pitched voice", "Abnormally ossified vertebrae", "Abnormally shaped carpal bones", "Abscess", "Absence of pubertal development", "Absence of secondary sex characteristics", "Absence of subcutaneous fat", "Absent axillary hair", "Absent brainstem auditory responses", "Absent distal interphalangeal creases", "Absent distal phalanges", "Absent earlobe", "Absent epiphyses", "Absent eyebrow", "Absent facial hair", "Absent fingernail", "Absent forearm bone", "Absent foveal reflex", "Absent frontal sinuses", "Absent hair", "Absent hand", "Absent hypoplastic paranasal sinuses", "Absent lacrimal punctum", "Absent nares", "Absent nipple", "Absent or minimally ossified vertebral bodies", "Absent outer dynein arms", "Absent palmar crease", "Absent phalangeal crease", "Absent septum pellucidum", "Absent shortened dynein arms", "Absent speech", "Absent sternal ossification", "Absent testis", "Absent thumb", "Absent thumbnail", "Absent tibia", "Absent toe", "Absent toenail", "Acanthocytosis", "Acantholysis", "Acanthosis nigricans", "Accelerated atherosclerosis", "Accelerated skeletal maturation", "Accessory oral frenulum", "Accessory spleen", "Acetabular dysplasia", "Acetabular spurs", "Achilles tendon contracture", "Achromatopsia", "Acidemia", "Acne", "Acne inversa", "Acquired abnormal hair pattern", "Acral blistering", "Acral ulceration", "Acromesomelia", "Acroparesthesia", "Action tremor", "Acute coronary syndrome", "Acute encephalopathy", "Acute hepatic failure", "Acute kidney injury", "Acute leukemia", "Acute lymphoblastic leukemia", "Acute myeloid leukemia", "Acute pancreatitis", "Acute phase response", "Acute rhabdomyolysis", "Addictive behavior", "Adducted thumb", "Adenocarcinoma of the colon", "Adenocarcinoma of the intestines", "Adenocarcinoma of the small intestine", "Adenoma sebaceum", "Adenomatous colonic polyposis", "Adipose tissue loss", "Adrenal hyperplasia", "Adrenal hypoplasia", "Adrenal insufficiency", "Adrenal overactivity", "Adrenocortical abnormality", "Adrenocortical adenoma", "Adrenocortical carcinoma", "Adrenocorticotropic hormone deficiency", "Adrenocorticotropic hormone excess", "Adrenocorticotropin deficient adrenal insufficiency", "Adult onset", "Advanced eruption of teeth", "Advanced ossification of carpal bones", "Agammaglobulinemia", "Aganglionic megacolon", "Agenesis of central incisor", "Agenesis of cerebellar vermis", "Agenesis of corpus callosum", "Agenesis of incisor", "Agenesis of lateral incisor", "Agenesis of maxillary incisor", "Agenesis of permanent teeth", "Aggressive behavior", "Agitation", "Agnosia", "Agyria", "Airway obstruction", "Akinesia", "Alacrima", "Albinism", "Albuminuria", "Alexia", "Alkalosis", "Allergic rhinitis", "Allergy", "Alopecia", "Alopecia of scalp", "Alopecia totalis", "Alopecia universalis", "Alternating esotropia", "Alveolar cell carcinoma", "Alveolar rhabdomyosarcoma", "Alveolar ridge overgrowth", "Amaurosis fugax", "Ambiguous genitalia", "Ambiguous genitalia female", "Ambiguous genitalia male", "Amblyopia", "Amegakaryocytic thrombocytopenia", "Amelogenesis imperfecta", "Amenorrhea", "Aminoaciduria", "Amniotic constriction ring", "Amyloidosis", "Amyotrophic lateral sclerosis", "Anal atresia", "Anal fissure", "Anal stenosis", "Anaphylactic shock", "Anarthria", "Anasarca", "Anemia of inadequate production", "Anemic pallor", "Anencephaly", "Angina pectoris", "Angioedema", "Angiofibromas", "Angioid streaks of the fundus", "Angiokeratoma", "Angular cheilitis", "Anhidrosis", "Aniridia", "Anisocoria", "Anisocytosis", "Anisopoikilocytosis", "Anisospondyly", "Ankle clonus", "Ankle flexion contracture", "Ankle weakness", "Ankyloblepharon", "Ankyloglossia", "Ankylosis", "Annular pancreas", "Anodontia", "Anomalous trichromacy", "Anomic aphasia", "Anonychia", "Anophthalmia", "Anorectal anomaly", "Anorexia", "Anosmia", "Anotia", "Antenatal onset", "Anterior open bite malocclusion", "Anterior pituitary dysgenesis", "Anterior plagiocephaly", "Anterior rib cupping", "Anterior uveitis", "Anteriorly placed anus", "Anteverted ears", "Anti thyroid peroxidase antibody positivity", "Antineutrophil antibody positivity", "Antinuclear antibody positivity", "Antiphospholipid antibody positivity", "Aortic aneurysm", "Aortic arch aneurysm", "Aortic atherosclerotic lesion", "Aortic dissection", "Aortic regurgitation", "Aortic root aneurysm", "Aortic valve calcification", "Aortic valve stenosis", "Aphasia", "Aphthous ulcer", "Aplasia cutis congenita", "Aplasia cutis congenita of scalp", "Aplasia cutis congenita on trunk or limbs", "Aplasia cutis congenita over the scalp vertex", "Aplasia hypoplasia affecting bones of the axial skeleton", "Aplasia hypoplasia affecting the anterior segment of the eye", "Aplasia hypoplasia affecting the eye", "Aplasia hypoplasia affecting the fundus", "Aplasia hypoplasia involving bones of the feet", "Aplasia hypoplasia involving bones of the lower limbs", "Aplasia hypoplasia involving bones of the thorax", "Aplasia hypoplasia involving bones of the upper limbs", "Aplasia hypoplasia involving forearm bones", "Aplasia hypoplasia involving the carpal bones", "Aplasia hypoplasia involving the femoral head and neck", "Aplasia hypoplasia involving the metacarpal bones", "Aplasia hypoplasia involving the musculature of the upper limbs", "Aplasia hypoplasia involving the nose", "Aplasia hypoplasia involving the pelvis", "Aplasia hypoplasia involving the sinuses", "Aplasia hypoplasia involving the skeletal musculature", "Aplasia hypoplasia involving the skeleton", "Aplasia hypoplasia involving the vertebral column", "Aplasia hypoplasia of fingers", "Aplasia hypoplasia of metatarsal bones", "Aplasia hypoplasia of the 2nd finger", "Aplasia hypoplasia of the 4th metacarpal", "Aplasia hypoplasia of the 5th finger", "Aplasia hypoplasia of the 5th metacarpal", "Aplasia hypoplasia of the abdominal wall musculature", "Aplasia hypoplasia of the bladder", "Aplasia hypoplasia of the breasts", "Aplasia hypoplasia of the capital femoral epiphysis", "Aplasia hypoplasia of the cerebellar vermis", "Aplasia hypoplasia of the cerebellum", "Aplasia hypoplasia of the cerebral white matter", "Aplasia hypoplasia of the clavicles", "Aplasia hypoplasia of the colon", "Aplasia hypoplasia of the distal phalanges of the hand", "Aplasia hypoplasia of the distal phalanges of the toes", "Aplasia hypoplasia of the distal phalanx of the thumb", "Aplasia hypoplasia of the ear", "Aplasia hypoplasia of the earlobes", "Aplasia hypoplasia of the epiglottis", "Aplasia hypoplasia of the extremities", "Aplasia hypoplasia of the eyebrow", "Aplasia hypoplasia of the eyelid", "Aplasia hypoplasia of the femur", "Aplasia hypoplasia of the fibula", "Aplasia hypoplasia of the gallbladder", "Aplasia hypoplasia of the hallux", "Aplasia hypoplasia of the humerus", "Aplasia hypoplasia of the lungs", "Aplasia hypoplasia of the middle phalanges of the toes", "Aplasia hypoplasia of the nails", "Aplasia hypoplasia of the nasal bone", "Aplasia hypoplasia of the nasal septum", "Aplasia hypoplasia of the nipples", "Aplasia hypoplasia of the optic nerve", "Aplasia hypoplasia of the ovary", "Aplasia hypoplasia of the palmar creases", "Aplasia hypoplasia of the patella", "Aplasia hypoplasia of the phalanges of the 2nd finger", "Aplasia hypoplasia of the phalanges of the hallux", "Aplasia hypoplasia of the phalanges of the hand", "Aplasia hypoplasia of the phalanges of the thumb", "Aplasia hypoplasia of the phalanges of the toes", "Aplasia hypoplasia of the proximal phalanges of the hand", "Aplasia hypoplasia of the pubic bone", "Aplasia hypoplasia of the radius", "Aplasia hypoplasia of the retina", "Aplasia hypoplasia of the ribs", "Aplasia hypoplasia of the sacrum", "Aplasia hypoplasia of the scapulae", "Aplasia hypoplasia of the skin", "Aplasia hypoplasia of the spleen", "Aplasia hypoplasia of the sternum", "Aplasia hypoplasia of the thumb", "Aplasia hypoplasia of the thymus", "Aplasia hypoplasia of the thyroid gland", "Aplasia hypoplasia of the tibia", "Aplasia hypoplasia of the tongue", "Aplasia hypoplasia of the tragus", "Aplasia hypoplasia of the ulna", "Aplasia hypoplasia of the uterus", "Aplasia hypoplasia of the uvula", "Aplasia hypoplasia of the vagina", "Aplasia hypoplasia of toe", "Aplasia involving bones of the extremities", "Aplasia involving bones of the lower limbs", "Aplasia of metacarpal bones", "Aplasia of the fingers", "Aplasia of the middle phalanx of the hand", "Aplasia of the phalanges of the hand", "Aplasia of the phalanges of the toes", "Aplasia of the proximal phalanges of the hand", "Aplasia of the semicircular canal", "Aplasia of the uterus", "Aplastic anemia", "Aplastic clavicle", "Aplastic hypoplastic lacrimal glands", "Aplastic hypoplastic toenail", "Apnea", "Apneic episodes in infancy", "Apneic episodes precipitated by illness fatigue stress", "Appendicular hypotonia", "Apraxia", "Aqueductal stenosis", "Arachnodactyly", "Arachnoid hemangiomatosis", "Areflexia", "Areflexia of lower limbs", "Arm dystonia", "Arnold chiari malformation", "Arnold chiari type i malformation", "Arrhinencephaly", "Arteria lusoria", "Arterial dissection", "Arterial rupture", "Arterial stenosis", "Arterial thrombosis", "Arteriosclerosis", "Arteriovenous malformation", "Arthralgia", "Arthritis", "Arthrogryposis multiplex congenita", "Arthropathy", "Ascending aortic dissection", "Ascending tubular aorta aneurysm", "Ascites", "Aspiration", "Aspiration pneumonia", "Asterixis", "Asthenia", "Asthma", "Astigmatism", "Astrocytoma", "Astrocytosis", "Asymmetric growth", "Asymmetric septal hypertrophy", "Asymmetry of the ears", "Asymmetry of the thorax", "Atelectasis", "Athetosis", "Atlantoaxial abnormality", "Atlantoaxial dislocation", "Atlantoaxial instability", "Atonic seizure", "Atopic dermatitis", "Atresia of the external auditory canal", "Atrial arrhythmia", "Atrial flutter", "Atrioventricular canal defect", "Atrophic scars", "Atrophy degeneration affecting the brainstem", "Atrophy degeneration affecting the central nervous system", "Atrophy degeneration affecting the cerebrum", "Atrophy degeneration involving the caudate nucleus", "Atrophy degeneration involving the corticospinal tracts", "Atrophy degeneration involving the spinal cord", "Atrophy of alveolar ridges", "Attention deficit hyperactivity disorder", "Attenuation of retinal blood vessels", "Atypical absence seizure", "Auditory hallucinations", "Autism", "Autistic behavior", "Autoamputation", "Autoamputation of digits", "Autoimmune antibody positivity", "Autoimmune hemolytic anemia", "Autoimmune thrombocytopenia", "Autoimmunity", "Autophagic vacuoles", "Autosomal dominant germline de novo mutation", "Avascular necrosis", "Avascular necrosis of the capital femoral epiphysis", "Axial dystonia", "Axial muscle weakness", "Axillary pterygium", "Axonal degeneration", "Axonal degeneration regeneration", "Axonal loss", "Axonal regeneration", "Azoospermia", "B cell lymphoma", "B lymphocytopenia", "Babinski sign", "Back pain", "Bacterial endocarditis", "Barrel shaped chest", "Barrett esophagus", "Basal cell carcinoma", "Basal ganglia calcification", "Basal ganglia cysts", "Basal ganglia gliosis", "Basilar invagination", "Beaded ribs", "Beaking of vertebral bodies", "Bell shaped thorax", "Benign neoplasm of the central nervous system", "Bicarbonaturia", "Biconcave vertebral bodies", "Bicornuate uterus", "Bicoronal synostosis", "Bifid epiglottis", "Bifid nasal tip", "Bifid ribs", "Bifid scrotum", "Bifid tongue", "Bifid uterus", "Bifid uvula", "Bilateral camptodactyly", "Bilateral cleft lip", "Bilateral cleft lip and palate", "Bilateral cleft palate", "Bilateral coxa valga", "Bilateral cryptorchidism", "Bilateral external ear deformity", "Bilateral microphthalmos", "Bilateral polymicrogyria", "Bilateral ptosis", "Bilateral sensorineural hearing impairment", "Bilateral single transverse palmar creases", "Bilateral talipes equinovarus", "Bilateral tonic clonic seizure", "Bilateral tonic clonic seizure with focal onset", "Bilateral tonic clonic seizure with generalized onset", "Bile duct proliferation", "Biliary atresia", "Biliary cirrhosis", "Biliary tract abnormality", "Biliary tract neoplasm", "Bimanual synkinesia", "Biparietal narrowing", "Bird like facies", "Birth length greater than 97th percentile", "Birth length less than 3rd percentile", "Biventricular hypertrophy", "Bladder diverticulum", "Bladder neoplasm", "Bleeding with minor or no trauma", "Blepharitis", "Blepharophimosis", "Blindness", "Blistering by anatomical location", "Blistering by histological location", "Bloodstream infectious agent", "Bloody diarrhea", "Blue irides", "Blue nevus", "Blue sclerae", "Blurred vision", "Bone cyst", "Bone fracture", "Bone marrow foam cells", "Bone marrow hypercellularity", "Bone marrow hypocellularity", "Bone pain", "Bone spicule pigmentation of the retina", "Bowel diverticulosis", "Bowing of the arm", "Bowing of the legs", "Brachycephaly", "Brachydactyly", "Brachyturricephaly", "Bradycardia", "Bradykinesia", "Brain imaging abnormality", "Brain neoplasm", "Brain stem compression", "Branchial anomaly", "Branchial cyst", "Branchial fistula", "Breast aplasia", "Breast carcinoma", "Breast hypoplasia", "Breathing dysregulation", "Breech presentation", "Brisk reflexes", "Brittle hair", "Broad alveolar ridges", "Broad based gait", "Broad chin", "Broad clavicles", "Broad columella", "Broad distal phalanx of finger", "Broad eyebrow", "Broad face", "Broad femoral neck", "Broad finger", "Broad foot", "Broad forehead", "Broad hallux phalanx", "Broad jaw", "Broad long bones", "Broad metacarpals", "Broad nail", "Broad nasal tip", "Broad neck", "Broad palm", "Broad phalanx of the toes", "Broad philtrum", "Broad ribs", "Broad thumb", "Broad toe", "Bronchiectasis", "Bronchitis", "Bronchomalacia", "Bronchospasm", "Bruising susceptibility", "Brushfield spots", "Bruxism", "Bulbar palsy", "Bulbar signs", "Bulbous nose", "Bull s eye maculopathy", "Bundle branch block", "Buphthalmos", "Burkitt lymphoma", "Butterfly vertebrae", "Cachexia", "Caesarian section", "Cafe au lait spot", "Calcific stippling", "Calcification of cartilage", "Calcification of the aorta", "Calcinosis", "Calcium nephrolithiasis", "Calcium oxalate nephrolithiasis", "Calf muscle pseudohypertrophy", "Calvarial hyperostosis", "Calvarial osteosclerosis", "Calvarial skull defect", "Camptodactyly of toe", "Capillary hemangioma", "Capillary malformation", "Capitate hamate fusion", "Carcinoid tumor", "Carcinoma", "Cardiac arrest", "Cardiac conduction abnormality", "Cardiac diverticulum", "Cardiac rhabdomyoma", "Cardiac shunt", "Cardiac valve calcification", "Cardiomegaly", "Cardiorespiratory arrest", "Cardiovascular calcification", "Carious teeth", "Carpal bone hypoplasia", "Carpal synostosis", "Cataplexy", "Caudate atrophy", "Cavernous hemangioma", "Cavum septum pellucidum", "Celiac disease", "Cellular immunodeficiency", "Cellulitis", "Central adrenal insufficiency", "Central apnea", "Central diabetes insipidus", "Central heterochromia", "Central hypothyroidism", "Central hypoventilation", "Central nervous system cyst", "Central primitive neuroectodermal tumor", "Central scotoma", "Central sleep apnea", "Central y shaped metacarpal", "Centrally nucleated skeletal muscle fibers", "Centrocecal scotoma", "Cerebellar atrophy", "Cerebellar cortical atrophy", "Cerebellar cyst", "Cerebellar dysplasia", "Cerebellar hemorrhage", "Cerebellar hypoplasia", "Cerebellar malformation", "Cerebellar vermis atrophy", "Cerebral calcification", "Cerebral cortical atrophy", "Cerebral dysmyelination", "Cerebral edema", "Cerebral hamartoma", "Cerebral hemorrhage", "Cerebral hypomyelination", "Cerebral hypoplasia", "Cerebral inclusion bodies", "Cerebral palsy", "Cerebral venous thrombosis", "Cerebral visual impairment", "Cerebral white matter atrophy", "Cerebral white matter hypoplasia", "Cervical cord compression", "Cervical kyphosis", "Cervical myelopathy", "Cervical ribs", "Cervical spinal canal stenosis", "Cervical spine instability", "Cervical subluxation", "Cessation of head growth", "Cheilitis", "Cherry red spot of the macula", "Chest pain", "Chilblains", "Childhood onset", "Childhood onset sensorineural hearing impairment", "Childhood onset truncal obesity", "Chills", "Choanal stenosis", "Choking episodes", "Cholangiocarcinoma", "Cholangitis", "Cholecystitis", "Cholestasis", "Cholestatic liver disease", "Chondrocalcinosis", "Chondrosarcoma", "Chordee", "Chorea", "Choreoathetosis", "Choriocarcinoma", "Chorioretinal atrophy", "Chorioretinal coloboma", "Chorioretinal degeneration", "Chorioretinal dysplasia", "Chorioretinal dystrophy", "Chorioretinal hypopigmentation", "Choroid plexus carcinoma", "Choroid plexus cyst", "Choroidal melanoma", "Choroidal neovascularization", "Chromosomal breakage induced by crosslinking agents", "Chromosomal breakage induced by ionizing radiation", "Chromosome breakage", "Chronic atrophic gastritis", "Chronic axonal neuropathy", "Chronic bronchitis", "Chronic constipation", "Chronic diarrhea", "Chronic fatigue", "Chronic hemolytic anemia", "Chronic hepatic failure", "Chronic infection", "Chronic kidney disease", "Chronic leukemia", "Chronic lung disease", "Chronic lymphatic leukemia", "Chronic mucocutaneous candidiasis", "Chronic neutropenia", "Chronic noninfectious lymphadenopathy", "Chronic oral candidiasis", "Chronic otitis media", "Chronic pulmonary obstruction", "Chronic rhinitis", "Chronic sinusitis", "Chylothorax", "Cigarette paper scars", "Cirrhosis", "Cleft hard palate", "Cleft lip", "Cleft soft palate", "Cleft upper lip", "Clinodactyly", "Clitoral hypoplasia", "Clonic seizure", "Clonus", "Cloverleaf skull", "Clubbing", "Clubbing of fingers", "Clubbing of toes", "Clumsiness", "Cns demyelination", "Cns hypomyelination", "Coarctation of aorta", "Coarse facial features", "Coarse hair", "Cochlear malformation", "Cognitive impairment", "Cogwheel rigidity", "Cold induced muscle cramps", "Colitis", "Collectionism", "Coloboma", "Colon cancer", "Color vision defect", "Color vision test abnormality", "Colorectal polyposis", "Colpocephaly", "Coma", "Combined immunodeficiency", "Communicating hydrocephalus", "Compensatory head posture", "Complete atrioventricular canal defect", "Complete duplication of phalanx of hand", "Complex febrile seizure", "Concave nail", "Concave nasal ridge", "Concentric hypertrophic cardiomyopathy", "Cone cone rod dystrophy", "Cone shaped epiphyses of the phalanges of the hand", "Cone shaped epiphysis", "Confetti like hypopigmented macules", "Confusion", "Congenital adrenal hyperplasia", "Congenital bilateral hip dislocation", "Congenital blindness", "Congenital contracture", "Congenital craniofacial dysostosis", "Congenital diaphragmatic hernia", "Congenital finger flexion contractures", "Congenital hemolytic anemia", "Congenital hepatic fibrosis", "Congenital hip dislocation", "Congenital hypothyroidism", "Congenital ichthyosiform erythroderma", "Congenital localized absence of skin", "Congenital malformation of the great arteries", "Congenital malformation of the left heart", "Congenital malformation of the right heart", "Congenital muscular dystrophy", "Congenital muscular torticollis", "Congenital nonbullous ichthyosiform erythroderma", "Congenital nystagmus", "Congenital onset", "Congenital posterior urethral valve", "Congenital ptosis", "Congenital sensorineural hearing impairment", "Congenital stationary night blindness", "Congenital thrombocytopenia", "Congestive heart failure", "Conical incisor", "Conical tooth", "Conjugated hyperbilirubinemia", "Conjunctival hamartoma", "Connective tissue nevi", "Conspicuously happy disposition", "Constipation", "Constitutional symptom", "Constriction of peripheral visual field", "Contiguous gene syndrome", "Contractures involving the joints of the feet", "Contractures of the joints of the lower limbs", "Contractures of the joints of the upper limbs", "Contractures of the large joints", "Convex nasal ridge", "Coombs positive hemolytic anemia", "Cor pulmonale", "Corneal dystrophy", "Corneal erosion", "Corneal neovascularization", "Corneal opacity", "Corneal scarring", "Corneal ulceration", "Coronal cleft vertebrae", "Coronal craniosynostosis", "Coronary artery aneurysm", "Coronary artery atherosclerosis", "Corpus callosum atrophy", "Cortical cataract", "Cortical dysplasia", "Cortical myoclonus", "Cortical thickening of long bone diaphyses", "Corticospinal tract hypoplasia", "Cough", "Coxa valga", "Coxa vara", "Crackles", "Cranial asymmetry", "Cranial hyperostosis", "Cranial nerve compression", "Craniofacial asymmetry", "Craniofacial dysostosis", "Craniofacial hyperostosis", "Craniofacial osteosclerosis", "Craniosynostosis", "Crossed fused renal ectopia", "Crumpled long bones", "Cryptorchidism", "Csf lymphocytic pleiocytosis", "Csf pleocytosis", "Cubitus valgus", "Cupped ear", "Cupped ribs", "Curly eyelashes", "Curly hair", "Cutaneous abscess", "Cutaneous amyloidosis", "Cutaneous cyst", "Cutaneous finger syndactyly", "Cutaneous melanoma", "Cutaneous photosensitivity", "Cutaneous syndactyly", "Cutaneous syndactyly of toes", "Cutis laxa", "Cutis marmorata", "Cyanosis", "Cyanotic episode", "Cyclopia", "Cystathioninemia", "Cystic hygroma", "Cystic liver disease", "Cystic renal dysplasia", "Cystinuria", "Cystoid macular edema", "Cytochrome c oxidase negative muscle fibers", "Dark urine", "Death in adolescence", "Death in adulthood", "Death in childhood", "Death in infancy", "Decerebrate rigidity", "Decreased absent ankle reflexes", "Decreased achilles reflex", "Decreased activity of mitochondrial complex i", "Decreased activity of mitochondrial complex ii", "Decreased activity of mitochondrial complex iii", "Decreased activity of mitochondrial complex iv", "Decreased activity of nadph oxidase", "Decreased activity of the pyruvate dehydrogenase complex", "Decreased adenosylcobalamin", "Decreased adipose tissue", "Decreased calvarial ossification", "Decreased cd4 cd8 ratio", "Decreased cervical spine flexion due to contractures of posterior cervical muscles", "Decreased cervical spine mobility", "Decreased circulating acth level", "Decreased circulating aldosterone level", "Decreased circulating androgen concentration", "Decreased circulating antibody level", "Decreased circulating copper concentration", "Decreased circulating cortisol level", "Decreased circulating follicle stimulating hormone concentration", "Decreased circulating gonadotropin concentration", "Decreased circulating iga level", "Decreased circulating igg level", "Decreased circulating igg subclass level", "Decreased circulating level of specific antibody", "Decreased circulating progesterone", "Decreased circulating total iga", "Decreased circulating total igg", "Decreased circulating total igm", "Decreased corneal reflex", "Decreased csf homovanillic acid", "Decreased facial expression", "Decreased fertility", "Decreased fertility in females", "Decreased fertility in males", "Decreased head circumference", "Decreased lacrimation", "Decreased ldl cholesterol concentration", "Decreased libido", "Decreased light and dark adapted electroretinogram amplitude", "Decreased lymphocyte apoptosis", "Decreased lymphocyte proliferation in response to mitogen", "Decreased mean corpuscular volume", "Decreased methylcobalamin", "Decreased methylmalonyl coa mutase activity", "Decreased muscle mass", "Decreased nasal nitric oxide", "Decreased number of large peripheral myelinated nerve fibers", "Decreased number of peripheral myelinated nerve fibers", "Decreased palmar creases", "Decreased patellar reflex", "Decreased plasma carnitine", "Decreased proportion of cd3 positive t cells", "Decreased proportion of cd4 positive helper t cells", "Decreased proportion of cd8 positive t cells", "Decreased pulmonary function", "Decreased serum complement c3", "Decreased serum complement c4", "Decreased serum insulin like growth factor 1", "Decreased serum iron", "Decreased size of nerve terminals", "Decreased specific anti polysaccharide antibody level", "Decreased specific antibody response to protein vaccine", "Decreased specific antibody response to vaccination", "Decreased specific pneumococcal antibody level", "Decreased testicular size", "Decreased urine output", "Deep palmar crease", "Deep philtrum", "Deep plantar creases", "Deep set nails", "Deep venous thrombosis", "Deeply set eye", "Defective dna repair after ultraviolet radiation damage", "Defective t cell proliferation", "Deformed rib cage", "Deformed sella turcica", "Deformed tarsal bones", "Degeneration of the lateral corticospinal tracts", "Degeneration of the striatum", "Dehydration", "Delayed ability to roll over", "Delayed ability to sit", "Delayed ability to stand", "Delayed ability to walk", "Delayed closure of the anterior fontanelle", "Delayed cns myelination", "Delayed cranial suture closure", "Delayed epiphyseal ossification", "Delayed eruption of permanent teeth", "Delayed eruption of primary teeth", "Delayed eruption of teeth", "Delayed fine motor development", "Delayed gross motor development", "Delayed menarche", "Delayed myelination", "Delayed ossification of carpal bones", "Delayed proximal femoral epiphyseal ossification", "Delayed puberty", "Delayed social development", "Delirium", "Delusions", "Dementia", "Demyelinating peripheral neuropathy", "Dental crowding", "Dental malocclusion", "Depletion of mitochondrial dna in muscle tissue", "Deposits immunoreactive to beta amyloid protein", "Depressed nasal bridge", "Depressed nasal ridge", "Depressed nasal tip", "Depression", "Dermal atrophy", "Dermal translucency", "Dermatological manifestations of systemic disorders", "Descending aortic dissection", "Desquamation of skin soon after birth", "Developmental cataract", "Developmental glaucoma", "Developmental regression", "Developmental stagnation", "Deviated nasal septum", "Deviation of the 2nd finger", "Deviation of the 3rd finger", "Deviation of the hallux", "Deviation of the hand or of fingers of the hand", "Deviation of the thumb", "Deviation of toes", "Diabetes insipidus", "Dialeptic seizure", "Diaphragmatic eventration", "Diaphragmatic paralysis", "Diaphragmatic weakness", "Diaphyseal sclerosis", "Diaphyseal thickening", "Diarrhea", "Diastasis recti", "Diastema", "Dicarboxylic aciduria", "Difficulty climbing stairs", "Difficulty in tongue movements", "Difficulty running", "Difficulty standing", "Difficulty walking", "Diffuse alveolar hemorrhage", "Diffuse cerebellar atrophy", "Diffuse cerebral atrophy", "Diffuse mesangial sclerosis", "Diffuse optic disc pallor", "Diffuse palmoplantar hyperkeratosis", "Diffuse white matter abnormalities", "Digenic inheritance", "Dilatation of the cerebral artery", "Dilatation of the ventricular cavity", "Dilated cardiomyopathy", "Dilated fourth ventricle", "Dilated third ventricle", "Dilation of lateral ventricles", "Dilation of virchow robin spaces", "Diminished ability to concentrate", "Diminished motivation", "Diminished movement", "Dimple chin", "Diplopia", "Disinhibition", "Displacement of the urethral meatus", "Disproportionate short limb short stature", "Disproportionate short stature", "Disproportionate short trunk short stature", "Disproportionate tall stature", "Disseminated intravascular coagulation", "Distal amyotrophy", "Distal arthrogryposis", "Distal joint laxity", "Distal lower limb amyotrophy", "Distal lower limb muscle weakness", "Distal muscle weakness", "Distal peripheral sensory neuropathy", "Distal sensory impairment", "Distal sensory impairment of all modalities", "Distal sensory loss of all modalities", "Distal symphalangism", "Distal upper limb amyotrophy", "Distal upper limb muscle weakness", "Disturbance of facial expression", "Dolichocephaly", "Double aortic arch", "Down sloping shoulders", "Downslanted palpebral fissures", "Downturned corners of mouth", "Drowsiness", "Drusen", "Dry hair", "Dry skin", "Duodenal adenocarcinoma", "Duodenal atresia", "Duodenal stenosis", "Duplicated collecting system", "Duplication involving bones of the feet", "Duplication of hand bones", "Duplication of the distal phalanx of hand", "Duplication of thumb phalanx", "Dysarthria", "Dyscalculia", "Dyschromatopsia", "Dysdiadochokinesis", "Dysesthesia", "Dysgammaglobulinemia", "Dysgenesis of the cerebellar vermis", "Dysgenesis of the hippocampus", "Dysgerminoma", "Dysgraphia", "Dyskinesia", "Dyslexia", "Dysmenorrhea", "Dysmetria", "Dysmetric saccades", "Dysostosis multiplex", "Dyspareunia", "Dysphagia", "Dysphasia", "Dysphonia", "Dysplasia of the femoral head", "Dysplastic corpus callosum", "Dyspnea", "Dystonia", "Dystrophic fingernails", "Dystrophic toenail", "Dysuria", "Ear pain", "Early onset absence seizures", "Early onset of sexual maturation", "Easy fatigability", "Ecchymosis", "Echolalia", "Eclabion", "Eclampsia", "Ectodermal dysplasia", "Ectopia lentis", "Ectopia pupillae", "Ectopic anus", "Ectopic calcification", "Ectopic kidney", "Ectrodactyly", "Ectropion", "Ectropion of lower eyelids", "Eczema", "Eczematoid dermatitis", "Edema of the dorsum of feet", "Edema of the dorsum of hands", "Eeg with abnormally slow frequencies", "Eeg with burst suppression", "Eeg with continuous slow activity", "Eeg with focal epileptiform discharges", "Eeg with focal sharp slow waves", "Eeg with focal sharp waves", "Eeg with focal spike waves", "Eeg with focal spikes", "Eeg with frontal epileptiform discharges", "Eeg with generalized sharp slow waves", "Eeg with generalized slow activity", "Eeg with irregular generalized spike and wave complexes", "Eeg with multifocal slow activity", "Eeg with polyspike wave complexes", "Eeg with spike wave complexes", "Elbow ankylosis", "Elbow flexion contracture", "Elevated alkaline phosphatase of bone origin", "Elevated calcitonin", "Elevated circulating alanine aminotransferase concentration", "Elevated circulating aspartate aminotransferase concentration", "Elevated circulating follicle stimulating hormone level", "Elevated circulating glutaric acid concentration", "Elevated circulating growth hormone concentration", "Elevated circulating long chain fatty acid concentration", "Elevated circulating parathyroid hormone level", "Elevated circulating thyroid stimulating hormone concentration", "Elevated creatine kinase after exercise", "Elevated diastolic blood pressure", "Elevated gamma glutamyltransferase level", "Elevated hemoglobin a1c", "Elevated hepatic transaminase", "Elevated lactate pyruvate ratio", "Elevated mean arterial pressure", "Elevated proportion of cd4 negative cd8 negative alpha beta regulatory t cells", "Elevated pulmonary artery pressure", "Elevated serum acid phosphatase", "Elevated systolic blood pressure", "Elevated tissue non specific alkaline phosphatase", "Elevated total serum tryptase", "Elevated urinary carboxylic acid", "Elevated urinary delta aminolevulinic acid", "Elevated urinary dicarboxylic acid level", "Elevated urinary monocarboxylic acid level", "Elfin facies", "Elliptocytosis", "Elongated superior cerebellar peduncle", "Embryonal neoplasm", "Embryonal renal neoplasm", "Emg abnormality", "Emg axonal abnormality", "Emg chronic denervation signs", "Emg decremental response of compound muscle action potential to repetitive nerve stimulation", "Emg impaired neuromuscular transmission", "Emg myopathic abnormalities", "Emg myotonic discharges", "Emg neuropathic changes", "Emg slow motor conduction", "Emotional lability", "Emphysema", "Enamel hypoplasia", "Encephalocele", "Encephalopathy", "Enchondroma", "Endocardial fibroelastosis", "Endocardial fibrosis", "Endocarditis", "Enlarged cerebellum", "Enlarged cisterna magna", "Enlarged interphalangeal joints", "Enlarged joints", "Enlarged kidney", "Enlarged metaphyses", "Enlarged ovaries", "Enlarged posterior fossa", "Enlarged thorax", "Enlargement of the costochondral junction", "Enlargement of the wrists", "Enterocolitis", "Enthesitis", "Entropion", "Enuresis", "Ependymoma", "Epicanthus", "Epicanthus inversus", "Epidermal acanthosis", "Epidermal hyperkeratosis", "Epidermal nevus", "Epidermoid cyst", "Epigastric pain", "Epileptic aura", "Epileptic encephalopathy", "Epileptic spasm", "Epiphora", "Epiphyseal dysplasia", "Epiphyseal stippling", "Epiretinal membrane", "Episodic ataxia", "Episodic hyperhidrosis", "Episodic hypertension", "Episodic pain", "Episodic respiratory distress", "Episodic tachypnea", "Episodic vomiting", "Epispadias", "Epistaxis", "Equinovarus deformity", "Equinus calcaneus", "Erectile dysfunction", "Erlenmeyer flask deformity of the femurs", "Eruption failure", "Erysipelas", "Erythema", "Erythema nodosum", "Erythematous papule", "Erythematous plaque", "Erythrocyte inclusion bodies", "Erythroderma", "Erythroid hyperplasia", "Erythroid hypoplasia", "Esodeviation", "Esophageal atresia", "Esophageal carcinoma", "Esophageal neoplasm", "Esophageal stenosis", "Esophageal stricture", "Esophageal ulceration", "Esophageal varix", "Esophagitis", "Ethylmalonic aciduria", "Eunuchoid habitus", "Euryblepharon", "Eversion of lateral third of lower eyelids", "Everted upper lip vermilion", "Exaggerated cupid s bow", "Exaggerated startle response", "Exanthem", "Excessive daytime somnolence", "Excessive salivation", "Excessive wrinkled skin", "Excessive wrinkling of palmar skin", "Exercise induced muscle cramps", "Exercise induced muscle fatigue", "Exercise induced muscle stiffness", "Exercise induced myalgia", "Exercise induced myoglobinuria", "Exercise induced rhabdomyolysis", "Exercise intolerance", "Exertional dyspnea", "Exodeviation", "Exostoses", "Expressive aphasia", "Expressive language delay", "External ear malformation", "External genital hypoplasia", "External ophthalmoplegia", "Extra axial cerebrospinal fluid accumulation", "Extrahepatic cholestasis", "Extramedullary hematopoiesis", "Extrapyramidal dyskinesia", "Extrapyramidal muscular rigidity", "Eyelid apraxia", "Eyelid coloboma", "Eyelid myoclonus", "Facial asymmetry", "Facial capillary hemangioma", "Facial cleft", "Facial diplegia", "Facial edema", "Facial erythema", "Facial grimacing", "Facial hemangioma", "Facial hyperostosis", "Facial hypertrichosis", "Facial hypotonia", "Facial myokymia", "Facial shape deformation", "Facial telangiectasia", "Failure of eruption of permanent teeth", "Failure to thrive", "Failure to thrive in infancy", "Fair hair", "Falls", "Fasciculations", "Fasting hyperinsulinemia", "Fasting hypoglycemia", "Fat malabsorption", "Fatigable weakness of bulbar muscles", "Fatigable weakness of distal limb muscles", "Fatigable weakness of respiratory muscles", "Fatigable weakness of skeletal muscles", "Fatigable weakness of swallowing muscles", "Fatiguable weakness of proximal limb muscles", "Fatigue", "Fatty replacement of skeletal muscle", "Feeding difficulties", "Feeding difficulties in infancy", "Female external genitalia in individual with 46 xy karyotype", "Female hypogonadism", "Female infertility", "Female pseudohermaphroditism", "Female reproductive system neoplasm", "Female sexual dysfunction", "Femoral bowing", "Femoral hernia", "Fetal akinesia sequence", "Fetal distress", "Fetal onset", "Fetal polyuria", "Fetal ultrasound soft marker", "Fever", "Fibroadenoma of the breast", "Fibrosarcoma", "Fibrous tissue neoplasm", "Fibular aplasia", "Fibular hypoplasia", "Fine hair", "Finger agnosia", "Finger clinodactyly", "Finger swelling", "Finger syndactyly", "Fingernail dysplasia", "Fingerprint intracellular accumulation of autofluorescent lipopigment storage material", "First degree atrioventricular block", "First dorsal interossei muscle weakness", "Flank pain", "Flared iliac wing", "Flared metaphysis", "Flared nostrils", "Flaring of rib cage", "Flat acetabular roof", "Flat cornea", "Flat face", "Flat forehead", "Flat nasal alae", "Flat occiput", "Flattened epiphysis", "Flattened femoral epiphysis", "Flattened femoral head", "Flexion contracture of digit", "Flexion contracture of thumb", "Fluctuations in consciousness", "Flushing", "Foam cells", "Focal aware seizure", "Focal cortical dysplasia", "Focal cortical dysplasia type ii", "Focal dystonia", "Focal emotional seizure", "Focal impaired awareness seizure", "Focal motor seizure", "Focal motor status epilepticus", "Focal myoclonic seizure", "Focal non motor seizure", "Focal onset seizure", "Focal segmental glomerulosclerosis", "Focal sensory seizure", "Focal t2 hyperintense basal ganglia lesion", "Focal t2 hyperintense brainstem lesion", "Focal tonic seizure", "Focal white matter lesions", "Follicular hyperkeratosis", "Follicular hyperplasia", "Follicular thyroid carcinoma", "Food allergy", "Food intolerance", "Foot acroosteolysis", "Foot dorsiflexor weakness", "Foot oligodactyly", "Fractures of the long bones", "Fragile nails", "Fragile skin", "Fragmented epiphyses", "Freckling", "Frequent falls", "Frontal balding", "Frontal cortical atrophy", "Frontal hirsutism", "Frontal lobe dementia", "Frontotemporal cerebral atrophy", "Frontotemporal dementia", "Full cheeks", "Fulminant hepatic failure", "Functional abnormality of male internal genitalia", "Functional abnormality of the gastrointestinal tract", "Functional abnormality of the inner ear", "Functional abnormality of the middle ear", "Functional intestinal obstruction", "Functional motor deficit", "Furrowed tongue", "Fused cervical vertebrae", "Fusion of the cerebellar hemispheres", "Gait ataxia", "Gait disturbance", "Gait imbalance", "Galactorrhea", "Ganglioneuroblastoma", "Ganglioneuroma", "Gangrene", "Gastric ulcer", "Gastritis", "Gastroesophageal reflux", "Gastrointestinal atresia", "Gastrointestinal carcinoma", "Gastrointestinal hemorrhage", "Gastrointestinal infarctions", "Gastrointestinal inflammation", "Gastrointestinal obstruction", "Gastrointestinal stroma tumor", "Gastroparesis", "Gastrostomy tube feeding in infancy", "Gaze evoked horizontal nystagmus", "Gaze evoked nystagmus", "Generalized abnormality of skin", "Generalized aminoaciduria", "Generalized amyotrophy", "Generalized clonic seizure", "Generalized dystonia", "Generalized edema", "Generalized hirsutism", "Generalized hyperkeratosis", "Generalized hyperpigmentation", "Generalized hyperreflexia", "Generalized hypertrichosis", "Generalized hypopigmentation", "Generalized hypopigmentation of hair", "Generalized hypotonia", "Generalized joint laxity", "Generalized limb muscle atrophy", "Generalized lipodystrophy", "Generalized lymphadenopathy", "Generalized muscle weakness", "Generalized myoclonic atonic seizure", "Generalized myoclonic seizure", "Generalized neonatal hypotonia", "Generalized onset motor seizure", "Generalized onset seizure", "Generalized osteoporosis", "Generalized osteosclerosis", "Generalized tonic seizure", "Genetic anticipation", "Genital neoplasm", "Genu recurvatum", "Genu valgum", "Genu varum", "Geographic atrophy", "Germ cell neoplasia", "Germinoma", "Giant platelets", "Giant somatosensory evoked potentials", "Gingival bleeding", "Gingival fibromatosis", "Gingival overgrowth", "Gingival recession", "Gingivitis", "Glaucoma", "Glioblastoma multiforme", "Glioma", "Gliosis", "Global brain atrophy", "Glomerular deposits", "Glomerular sclerosis", "Glomerulonephritis", "Glomerulopathy", "Glomus jugular tumor", "Glossitis", "Glossoptosis", "Glucose intolerance", "Glutaric aciduria", "Glycosuria", "Goiter", "Gonadal dysgenesis", "Gonadal neoplasm", "Gonadoblastoma", "Gonosomal inheritance", "Gout", "Gowers sign", "Grammar specific speech disorder", "Granulocytopenia", "Granulomatosis", "Gray matter heterotopia", "Gynecomastia", "Halitosis", "Hallucinations", "Hallux valgus", "Hamartoma", "Hamartoma of the eye", "Hamartoma of tongue", "Hamartomatous polyposis", "Hammertoe", "Hamstring contractures", "Hand apraxia", "Hand clenching", "Hand muscle weakness", "Hand oligodactyly", "Hand polydactyly", "Hand tremor", "Handgrip myotonia", "Happy demeanor", "Hashimoto thyroiditis", "Head banging", "Head titubation", "Head tremor", "Headache", "Heart block", "Heat intolerance", "Heinz bodies", "Helicobacter pylori infection", "Hemangioblastoma", "Hemangiomatosis", "Hematemesis", "Hematochezia", "Hematological neoplasm", "Hemianopia", "Hemiatrophy", "Hemifacial spasm", "Hemihypertrophy", "Hemimegalencephaly", "Hemiparesis", "Hemiplegia hemiparesis", "Hemivertebrae", "Hemoglobinuria", "Hemolytic anemia", "Hemophagocytosis", "Hemoptysis", "Hemorrhage of the eye", "Hemothorax", "Heparan sulfate excretion in urine", "Hepatic cysts", "Hepatic encephalopathy", "Hepatic failure", "Hepatic fibrosis", "Hepatic necrosis", "Hepatitis", "Hepatoblastoma", "Hepatocellular adenoma", "Hepatocellular carcinoma", "Hepatomegaly", "Hepatosplenomegaly", "Hereditary nonpolyposis colorectal carcinoma", "Hernia", "Herpes simplex encephalitis", "Heterochromia iridis", "Heterogeneous", "Heteronymous hemianopia", "Heterophoria", "Heterotaxy", "Heterotropia", "Hiatus hernia", "High anterior hairline", "High forehead", "High frequency hearing impairment", "High frequency sensorineural hearing impairment", "High hypermetropia", "High myopia", "High narrow palate", "High palate", "High pitched voice", "Highly arched eyebrow", "Hip contracture", "Hip dislocation", "Hip dysplasia", "Hip flexor weakness", "Hip osteoarthritis", "Hip pain", "Hip subluxation", "Hirsutism", "Hoarse cry", "Hoarse voice", "Hodgkin lymphoma", "Holoprosencephaly", "Homocystinuria", "Honeycomb lung", "Horizontal eyebrow", "Horizontal nystagmus", "Horizontal pendular nystagmus", "Horizontal ribs", "Horseshoe kidney", "Humeroradial synostosis", "Hydranencephaly", "Hydrocele testis", "Hydrocephalus", "Hydrops fetalis", "Hydroureter", "Hydroxyprolinuria", "Hyperactive deep tendon reflexes", "Hyperactive patellar reflex", "Hyperactivity", "Hyperacusis", "Hyperaldosteronism", "Hyperammonemia", "Hyperautofluorescent macular lesion", "Hyperautofluorescent retinal lesion", "Hypercalcemia", "Hyperchloremic acidosis", "Hypercholesterolemia", "Hypercoagulability", "Hyperconvex fingernails", "Hyperconvex nail", "Hypereosinophilia", "Hyperesthesia", "Hyperextensibility at wrists", "Hyperextensibility of the finger joints", "Hyperextensibility of the knee", "Hyperextensible skin", "Hypergalactosemia", "Hyperglycemia", "Hypergonadotropic hypogonadism", "Hypergranulosis", "Hyperhidrosis", "Hyperhomocystinemia", "Hyperinsulinemic hypoglycemia", "Hyperintensity of cerebral white matter on mri", "Hyperkalemia", "Hyperkeratosis", "Hyperkeratotic papule", "Hyperketonemia", "Hyperkinetic movements", "Hyperlipidemia", "Hyperlipoproteinemia", "Hyperlordosis", "Hypermagnesemia", "Hypermagnesiuria", "Hypermethioninemia", "Hypermetric saccades", "Hypermetropia", "Hypernatriuria", "Hyperorality", "Hyperostosis", "Hyperoxaluria", "Hyperparathyroidism", "Hyperphenylalaninemia", "Hyperphosphatemia", "Hyperphosphaturia", "Hyperpigmentation in sun exposed areas", "Hyperpigmentation of the fundus", "Hyperpigmentation of the skin", "Hyperpituitarism", "Hyperplasia of the maxilla", "Hyperreflexia", "Hyperreflexia in upper limbs", "Hypersomnia", "Hypersplenism", "Hypertelorism", "Hypertension associated with pheochromocytoma", "Hypertensive crisis", "Hyperthyroidism", "Hypertonia", "Hypertrichosis", "Hypertriglyceridemia", "Hypertrophic cardiomyopathy", "Hypertrophic nerve changes", "Hyperuricemia", "Hyperuricosuria", "Hyperventilation", "Hypoamylasemia", "Hypocalcemia", "Hypocalcemic seizures", "Hypocalcemic tetany", "Hypocalciuria", "Hypochloremia", "Hypocholesterolemia", "Hypochromia", "Hypochromic anemia", "Hypochromic microcytic anemia", "Hypodontia", "Hypoglycemic coma", "Hypoglycemic seizures", "Hypoglycorrhachia", "Hypogonadism", "Hypogonadotropic hypogonadism", "Hypohidrosis", "Hypoinsulinemia", "Hypointensity of cerebral white matter on mri", "Hypokalemia", "Hypokalemic alkalosis", "Hypokalemic metabolic alkalosis", "Hypoketotic hypoglycemia", "Hypokinesia", "Hypolipidemia", "Hypolipoproteinemia", "Hypomelanotic macule", "Hypomethioninemia", "Hypometric saccades", "Hypomimic face", "Hypoparathyroidism", "Hypophosphatemia", "Hypophosphatemic rickets", "Hypopigmentation of the fundus", "Hypopigmentation of the skin", "Hypopigmented macule", "Hypopigmented skin patches", "Hypopituitarism", "Hypoplasia of olfactory tract", "Hypoplasia of penis", "Hypoplasia of teeth", "Hypoplasia of the brainstem", "Hypoplasia of the corpus callosum", "Hypoplasia of the ear cartilage", "Hypoplasia of the epiglottis", "Hypoplasia of the femoral head", "Hypoplasia of the fovea", "Hypoplasia of the frontal lobes", "Hypoplasia of the iris", "Hypoplasia of the musculature", "Hypoplasia of the odontoid process", "Hypoplasia of the olfactory bulb", "Hypoplasia of the pons", "Hypoplasia of the primary teeth", "Hypoplasia of the radius", "Hypoplasia of the uterus", "Hypoplasia of the vagina", "Hypoplasia of the ventral pons", "Hypoplastic anemia", "Hypoplastic aortic arch", "Hypoplastic cervical vertebrae", "Hypoplastic dermoepidermal hemidesmosomes", "Hypoplastic facial bones", "Hypoplastic female external genitalia", "Hypoplastic fifth fingernail", "Hypoplastic fifth toenail", "Hypoplastic fingernail", "Hypoplastic frontal sinuses", "Hypoplastic heart", "Hypoplastic helices", "Hypoplastic hippocampus", "Hypoplastic ilia", "Hypoplastic iliac wing", "Hypoplastic labia majora", "Hypoplastic labia minora", "Hypoplastic nipples", "Hypoplastic pelvis", "Hypoplastic pubic rami", "Hypoplastic spleen", "Hypoplastic toenails", "Hypoplastic vertebral bodies", "Hypoproteinemia", "Hyporeflexia", "Hyporeflexia of lower limbs", "Hyporeflexia of upper limbs", "Hyposmia", "Hypotelorism", "Hypotension", "Hypothalamic gonadotropin releasing hormone deficiency", "Hypothalamic hamartoma", "Hypothalamic hypothyroidism", "Hypothermia", "Hypotriglyceridemia", "Hypouricemia", "Hypoventilation", "Hypovolemic shock", "Hypsarrhythmia", "Ichthyosis", "Ileus", "Imbalanced hemoglobin synthesis", "Immotile cilia", "Immotile sperm", "Immune dysregulation", "Immunodeficiency", "Immunologic hypersensitivity", "Impacted tooth", "Impaired adp induced platelet aggregation", "Impaired antigen specific response", "Impaired collagen induced platelet aggregation", "Impaired distal proprioception", "Impaired distal tactile sensation", "Impaired distal vibration sensation", "Impaired epinephrine induced platelet aggregation", "Impaired glucose tolerance", "Impaired horizontal smooth pursuit", "Impaired lymphocyte transformation with phytohemagglutinin", "Impaired mastication", "Impaired neutrophil bactericidal activity", "Impaired oropharyngeal swallow response", "Impaired pain sensation", "Impaired proprioception", "Impaired smooth pursuit", "Impaired social interactions", "Impaired t cell function", "Impaired tactile sensation", "Impaired tandem gait", "Impaired temperature sensation", "Impaired use of nonverbal behaviors", "Impaired vibration sensation at ankles", "Impaired vibration sensation in the lower limbs", "Impaired vibratory sensation", "Impaired visuospatial constructive cognition", "Impairment in personality functioning", "Impairment of activities of daily living", "Impotence", "Inability to walk", "Inappropriate antidiuretic hormone secretion", "Inappropriate behavior", "Inappropriate crying", "Inappropriate laughter", "Incisor macrodontia", "Incomitant strabismus", "Incomplete partition of the cochlea type ii", "Incomplete penetrance", "Incomprehensible speech", "Incoordination", "Increased adipose tissue", "Increased arm span", "Increased aspartate family amino acid level in urine", "Increased b cell count", "Increased blood pressure", "Increased blood urea nitrogen", "Increased body mass index", "Increased body weight", "Increased bone mineral density", "Increased c peptide level", "Increased cerebral lipofuscin", "Increased circulating acth level", "Increased circulating androgen concentration", "Increased circulating antibody level", "Increased circulating cortisol level", "Increased circulating gonadotropin level", "Increased circulating iga level", "Increased circulating igg level", "Increased circulating igm level", "Increased circulating interleukin 6", "Increased circulating lactate dehydrogenase concentration", "Increased circulating prolactin concentration", "Increased circulating renin level", "Increased connective tissue", "Increased csf lactate", "Increased density of long bones", "Increased endomysial connective tissue", "Increased fecal porphyrin", "Increased female libido", "Increased head circumference", "Increased hematocrit", "Increased hemoglobin", "Increased hepatic glycogen content", "Increased hepatocellular lipid droplets", "Increased intervertebral space", "Increased intracranial pressure", "Increased intramyocellular lipid droplets", "Increased laxity of ankles", "Increased ldl cholesterol concentration", "Increased level of hippuric acid in urine", "Increased level of l fucose in urine", "Increased mean corpuscular hemoglobin concentration", "Increased mean corpuscular volume", "Increased megakaryocyte count", "Increased muscle fatiguability", "Increased muscle glycogen content", "Increased muscle lipid content", "Increased nuchal translucency", "Increased overbite", "Increased proportion of cd25 mast cells", "Increased proteinogenic amino acid level in urine", "Increased sensitivity to ionizing radiation", "Increased serine family amino acid in urine", "Increased serum iron", "Increased serum lactate", "Increased serum pyruvate", "Increased serum serotonin", "Increased serum testosterone level", "Increased skull ossification", "Increased sulfur amino acid level in urine", "Increased susceptibility to fractures", "Increased theta frequency activity in eeg", "Increased total bilirubin", "Increased urinary cortisol level", "Increased urinary non proteinogenic amino acid level", "Increased urine alpha ketoglutarate concentration", "Increased urine proteinogenic amino acid derivative level", "Increased vertebral height", "Increased vldl cholesterol concentration", "Ineffective esophageal peristalsis", "Infantile axial hypotonia", "Infantile encephalopathy", "Infantile muscular hypotonia", "Infantile onset", "Infantile spasms", "Infection related seizure", "Infectious encephalitis", "Inferior lens subluxation", "Inferior vermis hypoplasia", "Infertility", "Inflammation of the large intestine", "Inflammatory abnormality of the eye", "Inflexible adherence to routines or rituals", "Inguinal freckling", "Inguinal hernia", "Insidious onset", "Insomnia", "Inspiratory stridor", "Insulin resistance", "Insulin resistant diabetes mellitus", "Intellectual disability borderline", "Intellectual disability mild", "Intellectual disability moderate", "Intellectual disability profound", "Intellectual disability progressive", "Intellectual disability severe", "Intercostal muscle weakness", "Interictal eeg abnormality", "Interlobular septal thickening", "Intermittent diarrhea", "Intermittent episodes of respiratory insufficiency due to muscle weakness", "Internally nucleated skeletal muscle fibers", "Interrupted aortic arch", "Interstitial cardiac fibrosis", "Interstitial pneumonitis", "Intervertebral space narrowing", "Intestinal atresia", "Intestinal bleeding", "Intestinal fistula", "Intestinal hypoplasia", "Intestinal malrotation", "Intestinal polyp", "Intestinal pseudo obstruction", "Intraalveolar phospholipid accumulation", "Intracellular accumulation of autofluorescent lipopigment storage material", "Intracranial hemorrhage", "Intracranial meningioma", "Intractable diarrhea", "Intrauterine growth retardation", "Intrinsic hand muscle atrophy", "Intussusception", "Inverted nipples", "Involuntary movements", "Iridocyclitis", "Iris atrophy", "Iris coloboma", "Iris hypopigmentation", "Iron accumulation in brain", "Iron accumulation in globus pallidus", "Iron deficiency anemia", "Irregular acetabular roof", "Irregular capital femoral epiphysis", "Irregular epiphyses", "Irregular femoral epiphysis", "Irregular hyperpigmentation", "Irregular iliac crest", "Irregular menstruation", "Irregular vertebral endplates", "Irritability", "Ischemic stroke", "Ivory epiphyses", "J shaped sella turcica", "Jaundice", "Jerky head movements", "Jerky ocular pursuit movements", "Joint contracture of the 5th finger", "Joint contracture of the hand", "Joint contractures involving the joints of the feet", "Joint dislocation", "Joint hemorrhage", "Joint hyperflexibility", "Joint hypermobility", "Joint laxity", "Joint stiffness", "Joint subluxation", "Joint swelling", "Juvenile aseptic necrosis", "Juvenile cataract", "Juvenile myelomonocytic leukemia", "Juvenile onset", "Juvenile rheumatoid arthritis", "Keloids", "Keratitis", "Keratoconjunctivitis", "Keratosis pilaris", "Ketoacidosis", "Ketonuria", "Ketosis", "Ketotic hypoglycemia", "Kinetic tremor", "Kinked brainstem", "Knee clonus", "Knee dislocation", "Knee flexion contracture", "Kyphoscoliosis", "Kyphosis", "Labial hypertrophy", "Lack of insight", "Lack of peer relationships", "Lack of skin elasticity", "Lack of t cell function", "Lacrimal duct atresia", "Lacrimal duct stenosis", "Lacrimation abnormality", "Lactic acidosis", "Lacticaciduria", "Lactose intolerance", "Lagopthalmos", "Lambdoidal craniosynostosis", "Language impairment", "Large basal ganglia", "Large beaked nose", "Large earlobe", "Large face", "Large fleshy ears", "Large for gestational age", "Large foramen magnum", "Large forehead", "Large hands", "Large iliac wing", "Large intestinal polyposis", "Large placenta", "Large sella turcica", "Laryngeal cleft", "Laryngeal dystonia", "Laryngeal hypoplasia", "Laryngeal stenosis", "Laryngeal stridor", "Laryngomalacia", "Laryngotracheomalacia", "Late onset", "Lateral clavicle hook", "Leber optic atrophy", "Left atrial enlargement", "Left bundle branch block", "Left to right shunt", "Left ventricular hypertrophy", "Left ventricular noncompaction cardiomyopathy", "Left ventricular outflow tract obstruction", "Left ventricular systolic dysfunction", "Leg muscle stiffness", "Leiomyosarcoma", "Lens subluxation", "Lenticonus", "Lethal skeletal dysplasia", "Lethargy", "Leukemia", "Leukocytosis", "Leukodystrophy", "Leukoencephalopathy", "Leukonychia", "Leukopenia", "Lewy bodies", "Leydig cell neoplasia", "Lichenification", "Limb ataxia", "Limb dysmetria", "Limb dystonia", "Limb fasciculations", "Limb girdle muscle atrophy", "Limb girdle muscle weakness", "Limb girdle muscular dystrophy", "Limb hypertonia", "Limb joint contracture", "Limb muscle weakness", "Limb myoclonus", "Limb pain", "Limb tremor", "Limb undergrowth", "Limbal dermoid", "Limitation of joint mobility", "Limitation of knee mobility", "Limitation of movement at ankles", "Limitation of neck motion", "Limited elbow extension", "Limited elbow movement", "Limited extraocular movements", "Limited hip extension", "Limited hip movement", "Limited knee extension", "Limited wrist extension", "Limited wrist movement", "Lingual dystonia", "Lipid accumulation in hepatocytes", "Lipoatrophy", "Lipodystrophy", "Lipoma", "Lissencephaly", "Liver abscess", "Lobulated tongue", "Localized hirsutism", "Localized osteoporosis", "Localized skin lesion", "Long clavicles", "Long ear", "Long eyelashes", "Long fingers", "Long foot", "Long hallux", "Long neck", "Long nose", "Long palm", "Long palpebral fissure", "Long penis", "Long philtrum", "Long thorax", "Long toe", "Long upper lip", "Lop ear", "Loss of ability to walk", "Loss of consciousness", "Loss of eyelashes", "Loss of purkinje cells in the cerebellar vermis", "Loss of speech", "Loss of subcutaneous adipose tissue in limbs", "Loss of voice", "Low alkaline phosphatase", "Low anterior hairline", "Low apgar score", "Low back pain", "Low frustration tolerance", "Low grade fever", "Low hanging columella", "Low levels of vitamin d", "Low molecular weight proteinuria", "Low plasma citrulline", "Low posterior hairline", "Low set nipples", "Low set posteriorly rotated ears", "Lower extremity joint dislocation", "Lower eyelid coloboma", "Lower limb amyotrophy", "Lower limb asymmetry", "Lower limb hyperreflexia", "Lower limb hypertonia", "Lower limb metaphyseal irregularity", "Lower limb muscle weakness", "Lower limb pain", "Lower limb spasticity", "Lower limb undergrowth", "Lumbar hyperlordosis", "Lumbar kyphosis", "Lumbar scoliosis", "Lung adenocarcinoma", "Lymphadenitis", "Lymphangiectasis", "Lymphangioma", "Lymphedema", "Lymphocytosis", "Lymphoma", "Lymphopenia", "Lymphoproliferative disorder", "Macrocephaly at birth", "Macrocytic anemia", "Macrodactyly", "Macrodontia", "Macrodontia of permanent maxillary central incisor", "Macroglossia", "Macrogyria", "Macroorchidism", "Macroscopic hematuria", "Macrotia", "Macrovesicular hepatic steatosis", "Macular atrophy", "Macular coloboma", "Macular degeneration", "Macular hyperpigmentation", "Macular hypoplasia", "Macular purpura", "Macular thickening", "Macule", "Malabsorption", "Malar prominence", "Malar rash", "Male hypogonadism", "Male infertility", "Male pseudohermaphroditism", "Male reproductive system neoplasm", "Male sexual dysfunction", "Malignant genitourinary tract tumor", "Malignant hyperthermia", "Malignant neoplasm of the central nervous system", "Malnutrition", "Malrotation of small bowel", "Mandibular aplasia", "Mandibular prognathia", "Mania", "Mask like facies", "Mastoiditis", "Maternal hypertension", "Maturity onset diabetes of the young", "Meconium stained amniotic fluid", "Medial flaring of the eyebrow", "Median cleft lip", "Median cleft palate", "Mediastinal lymphadenopathy", "Medullary nephrocalcinosis", "Medulloblastoma", "Megalencephaly", "Megaloblastic anemia", "Megalocornea", "Melanocytic nevus", "Melanoma", "Melena", "Membranoproliferative glomerulonephritis", "Memory impairment", "Meningioma", "Meningitis", "Meningocele", "Meningoencephalocele", "Menorrhagia", "Mental deterioration", "Mesoaxial hand polydactyly", "Mesoaxial polydactyly", "Mesomelia", "Metabolic acidosis", "Metabolic alkalosis", "Metacarpophalangeal joint contracture", "Metamorphopsia", "Metaphyseal chondrodysplasia", "Metaphyseal cupping", "Metaphyseal dysplasia", "Metaphyseal irregularity", "Metaphyseal sclerosis", "Metaphyseal spurs", "Metaphyseal striations", "Metaphyseal widening", "Metatarsal synostosis", "Metatarsus adductus", "Metatarsus valgus", "Methemoglobinemia", "Methylmalonic acidemia", "Methylmalonic aciduria", "Metopic synostosis", "Metrorrhagia", "Microcornea", "Microcytic anemia", "Microdontia", "Microglossia", "Micrographia", "Micromelia", "Micronodular cirrhosis", "Micropenis", "Microphallus", "Microretrognathia", "Microscopic hematuria", "Microtia third degree", "Microvesicular hepatic steatosis", "Middle age onset", "Midface retrusion", "Midline defect of the nose", "Migraine", "Mild global developmental delay", "Mild hearing impairment", "Mild microcephaly", "Mild postnatal growth retardation", "Mild short stature", "Mildly elevated creatine kinase", "Milia", "Minicore myopathy", "Minimal change glomerulonephritis", "Miosis", "Misalignment of incisors", "Missing ribs", "Mitochondrial inheritance", "Mitochondrial myopathy", "Mitochondrial respiratory chain defects", "Mitral stenosis", "Mitral valve calcification", "Mitral valve prolapse", "Mitten deformity", "Mixed demyelinating and axonal polyneuropathy", "Mixed hearing impairment", "Mixed hypo and hyperpigmentation of the skin", "Moderate albuminuria", "Moderate global developmental delay", "Moderate sensorineural hearing impairment", "Moderately reduced visual acuity", "Moderately short stature", "Molar tooth sign on mri", "Molluscoid pseudotumors", "Molluscum contagiosum", "Monochromacy", "Monocytosis", "Monotonic speech", "Mood swings", "Morning glory anomaly", "Morning myoclonic jerks", "Morphological abnormality of the corticospinal tract", "Morphological abnormality of the middle ear", "Morphological abnormality of the pyramidal tract", "Morphological abnormality of the vestibule of the inner ear", "Mortality aging", "Motor axonal neuropathy", "Motor delay", "Motor deterioration", "Motor neuron atrophy", "Motor polyneuropathy", "Motor regression", "Motor seizure", "Motor tics", "Mottled pigmentation", "Movement abnormality of the tongue", "Moyamoya phenomenon", "Mucosal telangiectasiae", "Multicystic kidney dysplasia", "Multifactorial inheritance", "Multifocal cerebral white matter abnormalities", "Multifocal epileptiform discharges", "Multifocal seizures", "Multiple cafe au lait spots", "Multiple enchondromatosis", "Multiple exostoses", "Multiple gastric polyps", "Multiple glomerular cysts", "Multiple impacted teeth", "Multiple joint contractures", "Multiple joint dislocation", "Multiple lentigines", "Multiple lipomas", "Multiple mitochondrial dna deletions", "Multiple myeloma", "Multiple prenatal fractures", "Multiple renal cysts", "Multiple rib fractures", "Multiple rows of eyelashes", "Multiple suture craniosynostosis", "Muscle abnormality related to mitochondrial dysfunction", "Muscle fiber atrophy", "Muscle fiber inclusion bodies", "Muscle fiber necrosis", "Muscle fiber splitting", "Muscle fiber tubular inclusions", "Muscle fibrillation", "Muscle flaccidity", "Muscle hypertrophy of the lower extremities", "Muscle spasm", "Muscle stiffness", "Muscle weakness", "Muscular dystrophy", "Muscular hypotonia of the trunk", "Muscular ventricular septal defect", "Mutism", "Myalgia", "Mydriasis", "Myelodysplasia", "Myelofibrosis", "Myeloid leukemia", "Myelomeningocele", "Myelopathy", "Myeloproliferative disorder", "Myocardial fibrosis", "Myoclonic seizure", "Myoclonic spasms", "Myoclonus", "Myofibrillar myopathy", "Myoglobinuria", "Myokymia", "Myopathic facies", "Myopathy", "Myopia", "Myositis", "Myotonia", "Naevus flammeus of the eyelid", "Nail dysplasia", "Nail dystrophy", "Nail pits", "Narrow face", "Narrow foot", "Narrow foramen obturatorium", "Narrow forehead", "Narrow iliac wing", "Narrow internal auditory canal", "Narrow jaw", "Narrow mouth", "Narrow nasal bridge", "Narrow nasal ridge", "Narrow nose", "Narrow palate", "Narrow palm", "Narrow palpebral fissure", "Narrow pelvis bone", "Narrow vertebral interpedicular distance", "Nasal congestion", "Nasal regurgitation", "Nasal speech", "Nasogastric tube feeding", "Nasogastric tube feeding in infancy", "Nasolacrimal duct obstruction", "Natal tooth", "Nausea", "Nausea and vomiting", "Neck flexor weakness", "Neck muscle weakness", "Negativism", "Nemaline bodies", "Neonatal alloimmune thrombocytopenia", "Neonatal asphyxia", "Neonatal breathing dysregulation", "Neonatal death", "Neonatal hyperbilirubinemia", "Neonatal hypoglycemia", "Neonatal hypotonia", "Neonatal insulin dependent diabetes mellitus", "Neonatal onset", "Neonatal respiratory distress", "Neoplasm", "Neoplasm by histology", "Neoplasm of fatty tissue", "Neoplasm of head and neck", "Neoplasm of striated muscle", "Neoplasm of the adrenal cortex", "Neoplasm of the adrenal gland", "Neoplasm of the breast", "Neoplasm of the colon", "Neoplasm of the ear", "Neoplasm of the endocrine system", "Neoplasm of the eye", "Neoplasm of the gallbladder", "Neoplasm of the gastrointestinal tract", "Neoplasm of the genitourinary tract", "Neoplasm of the heart", "Neoplasm of the inner ear", "Neoplasm of the large intestine", "Neoplasm of the larynx", "Neoplasm of the liver", "Neoplasm of the male external genitalia", "Neoplasm of the middle ear", "Neoplasm of the nervous system", "Neoplasm of the oral cavity", "Neoplasm of the pancreas", "Neoplasm of the parathyroid gland", "Neoplasm of the peripheral nervous system", "Neoplasm of the pituitary gland", "Neoplasm of the rectum", "Neoplasm of the respiratory system", "Neoplasm of the skeletal system", "Neoplasm of the skin", "Neoplasm of the small intestine", "Neoplasm of the stomach", "Neoplasm of the thymus", "Neoplasm of the thyroid gland", "Neoplasm of the tongue", "Neoplasm of the tracheobronchial system", "Nephritis", "Nephrocalcinosis", "Nephrogenic diabetes insipidus", "Nephrolithiasis", "Nephronophthisis", "Nephropathy", "Nephrotic syndrome", "Neuralgia", "Neurodegeneration", "Neuroendocrine neoplasm", "Neurofibrillary tangles", "Neurofibromas", "Neurogenic bladder", "Neuroinflammation", "Neuromuscular dysphagia", "Neuronal loss in basal ganglia", "Neuronal loss in central nervous system", "Neuronal loss in the cerebral cortex", "Neuropathic arthropathy", "Neutropenia in presence of anti neutropil antibodies", "Neutrophilia", "Nevus", "Night sweats", "No social interaction", "Nocturia", "Nocturnal hypoventilation", "Nocturnal seizures", "Nodular goiter", "Non hodgkin lymphoma", "Non medullary thyroid carcinoma", "Non midline cleft lip", "Non midline cleft palate", "Non motor seizure", "Non obstructive azoospermia", "Noncommunicating hydrocephalus", "Noncompaction cardiomyopathy", "Nonimmune hydrops fetalis", "Nonketotic hypoglycemia", "Nonprogressive", "Nonprogressive cerebellar ataxia", "Nonprogressive encephalopathy", "Nonspherocytic hemolytic anemia", "Normochromic anemia", "Normocytic anemia", "Nuchal rigidity", "Nuclear cataract", "Numerous nevi", "Numerous pigmented freckles", "Nyctalopia", "Nystagmus induced head nodding", "Obsessive compulsive behavior", "Obsessive compulsive trait", "Obstructive sleep apnea", "Occipital cortical atrophy", "Occipital encephalocele", "Occipital meningocele", "Ocular albinism", "Ocular anterior segment dysgenesis", "Ocular pain", "Oculogyric crisis", "Oculomotor apraxia", "Oculomotor nerve palsy", "Odontogenic neoplasm", "Oligoarthritis", "Oligodactyly", "Oligodontia", "Oligohydramnios", "Oligomenorrhea", "Oligosacchariduria", "Oligospermia", "Oliguria", "Olivopontocerebellar atrophy", "Olivopontocerebellar hypoplasia", "Omphalocele", "Onion bulb formation", "Onset", "Onychogryposis", "Onychogryposis of toenails", "Onycholysis", "Onychomycosis", "Open angle glaucoma", "Open bite", "Open mouth", "Open operculum", "Ophthalmoparesis", "Opisthotonus", "Opportunistic infection", "Opsoclonus", "Optic atrophy", "Optic disc coloboma", "Optic disc hypoplasia", "Optic disc pallor", "Optic nerve dysplasia", "Optic nerve hypoplasia", "Optic neuropathy", "Oral aversion", "Oral cavity bleeding", "Oral cleft", "Oral leukoplakia", "Oral mucosal blisters", "Oral pharyngeal dysphagia", "Oral ulcer", "Orchitis", "Organic aciduria", "Orofacial dyskinesia", "Oromandibular dystonia", "Oromotor apraxia", "Oroticaciduria", "Orthokeratosis", "Orthopnea", "Orthostatic hypotension", "Orthostatic hypotension due to autonomic dysfunction", "Osteoarthritis", "Osteochondroma", "Osteochondrosis", "Osteolysis", "Osteolysis involving bones of the feet", "Osteolysis involving bones of the upper limbs", "Osteolytic defects of the distal phalanges of the hand", "Osteomalacia", "Osteomyelitis", "Osteopenia", "Osteopetrosis", "Osteoporosis", "Osteosarcoma", "Otitis media", "Otosclerosis", "Oval face", "Ovarian carcinoma", "Ovarian cyst", "Ovarian gonadoblastoma", "Ovarian neoplasm", "Ovarian papillary adenocarcinoma", "Overfolding of the superior helices", "Overfriendliness", "Overgrowth", "Overhanging nasal tip", "Overlapping fingers", "Overlapping toe", "Overriding aorta", "Overtubulated long bones", "Overweight", "Ovoid vertebral bodies", "Ovotestis", "Pace of progression", "Pain", "Pain in head and neck region", "Pain insensitivity", "Painless fractures due to injury", "Pallor", "Palmar hyperhidrosis", "Palmar pits", "Palmar telangiectasia", "Palmoplantar blistering", "Palmoplantar cutis laxa", "Palmoplantar hyperhidrosis", "Palpebral edema", "Palpitations", "Pancreatic adenocarcinoma", "Pancreatic cysts", "Pancreatic endocrine tumor", "Pancreatic fibrosis", "Pancreatic hypoplasia", "Pancreatic islet cell hyperplasia", "Pancreatitis", "Pancytopenia", "Panhypogammaglobulinemia", "Panhypopituitarism", "Panniculitis", "Papillary renal cell carcinoma", "Papillary thyroid carcinoma", "Papilledema", "Papilloma", "Papule", "Paracentral scotoma", "Paraganglioma", "Parakeratosis", "Paralysis", "Paranoia", "Paraparesis", "Paraplegia", "Paraplegia paraparesis", "Parasomnia", "Parathyroid adenoma", "Parathyroid carcinoma", "Parathyroid hyperplasia", "Paresthesia", "Parietal bossing", "Parietal cortical atrophy", "Parietal foramina", "Parkinsonism", "Parkinsonism with favorable response to dopaminergic medication", "Paronychia", "Paroxysmal bursts of laughter", "Paroxysmal dystonia", "Paroxysmal involuntary eye movements", "Paroxysmal ventricular tachycardia", "Partial absence of thumb", "Partial agenesis of the corpus callosum", "Partial albinism", "Partial anomalous pulmonary venous return", "Partial duplication of the phalanx of hand", "Patchy alopecia", "Patchy changes of bone mineral density", "Patchy hypopigmentation of hair", "Patchy palmoplantar hyperkeratosis", "Patellar aplasia", "Patellar dislocation", "Patellar hypoplasia", "Patellar subluxation", "Patent ductus arteriosus", "Patent foramen ovale", "Pathologic fracture", "Pectus carinatum", "Pectus excavatum", "Pectus excavatum of inferior sternum", "Pedal edema", "Pediatric onset", "Pelvic girdle muscle weakness", "Pelvic kidney", "Pendular nystagmus", "Penetrating foot ulcers", "Peptic ulcer", "Perianal abscess", "Periauricular skin pits", "Pericardial effusion", "Pericarditis", "Perifoveal ring of hyperautofluorescence", "Perimembranous ventricular septal defect", "Perineal fistula", "Periodic paralysis", "Periodontitis", "Periorbital edema", "Periorbital fullness", "Peripheral arterial stenosis", "Peripheral axonal degeneration", "Peripheral axonal neuropathy", "Peripheral cyanosis", "Peripheral demyelination", "Peripheral edema", "Peripheral hypermyelination", "Peripheral hypomyelination", "Peripheral neuropathy", "Peripheral opacification of the cornea", "Peripheral pulmonary artery stenosis", "Peripheral retinal avascularization", "Peripheral visual field loss", "Periportal fibrosis", "Perisylvian polymicrogyria", "Peritoneal abscess", "Peritonitis", "Periventricular cysts", "Periventricular heterotopia", "Periventricular leukomalacia", "Periventricular nodular heterotopia", "Periventricular white matter hyperintensities", "Peroneal muscle atrophy", "Perseveration", "Persistence of hemoglobin f", "Persistence of primary teeth", "Persistent ebv viremia", "Persistent head lag", "Personality changes", "Pes cavus", "Pes planus", "Pes valgus", "Petechiae", "Peters anomaly", "Phalangeal dislocation", "Pharyngitis", "Phenotypic variability", "Pheochromocytoma", "Phimosis", "Phocomelia", "Phonophobia", "Photophobia", "Photopsia", "Photoreceptor layer loss on macular oct", "Phthisis bulbi", "Physical urticaria", "Pierre robin sequence", "Pigmentary retinopathy", "Pili canaliculi", "Pili torti", "Pilomatrixoma", "Pineal cyst", "Pituitary adenoma", "Pituitary growth hormone cell adenoma", "Pituitary hypothyroidism", "Pituitary prolactin cell adenoma", "Plagiocephaly", "Plantar hyperkeratosis", "Platybasia", "Platyspondyly", "Pleural effusion", "Pleuritis", "Pneumonia", "Pneumothorax", "Poikilocytosis", "Poikiloderma", "Pointed chin", "Polar cataract", "Pollakisuria", "Polyarticular arthropathy", "Polyclonal elevation of igm", "Polycystic kidney dysplasia", "Polycystic liver disease", "Polycythemia", "Polydactyly", "Polygenic inheritance", "Polyhydramnios", "Polymicrogyria", "Polyneuropathy", "Polyphagia", "Polysplenia", "Polyuria", "Pontocerebellar atrophy", "Poor appetite", "Poor coordination", "Poor eye contact", "Poor fine motor coordination", "Poor gross motor coordination", "Poor head control", "Poor motor coordination", "Poor speech", "Poor suck", "Poor wound healing", "Popliteal pterygium", "Porencephalic cyst", "Porokeratosis", "Porphyrinuria", "Portal fibrosis", "Portal vein thrombosis", "Positional foot deformity", "Positive romberg sign", "Post partum hemorrhage", "Postaxial foot polydactyly", "Postaxial hand polydactyly", "Postaxial polydactyly", "Posterior blepharitis", "Posterior embryotoxon", "Posterior fossa cyst", "Posterior pharyngeal cleft", "Posterior pituitary dysgenesis", "Posterior polar cataract", "Posterior subcapsular cataract", "Posteriorly rotated ears", "Postexertional malaise", "Postnatal growth retardation", "Postural instability", "Postural tremor", "Potter facies", "Preauricular skin tag", "Preaxial foot polydactyly", "Preaxial hand polydactyly", "Preaxial polydactyly", "Precocious atherosclerosis", "Predominantly lower limb lymphedema", "Prelingual sensorineural hearing impairment", "Premature adrenarche", "Premature arteriosclerosis", "Premature birth", "Premature coronary artery atherosclerosis", "Premature graying of hair", "Premature loss of primary teeth", "Premature loss of teeth", "Premature osteoarthritis", "Premature ovarian insufficiency", "Premature pubarche", "Premature rupture of membranes", "Premature skin wrinkling", "Premature thelarche", "Premature ventricular contraction", "Prematurely aged appearance", "Prenatal maternal abnormality", "Prenatal movement abnormality", "Primary adrenal insufficiency", "Primary amenorrhea", "Primary congenital glaucoma", "Primary gonadal insufficiency", "Primary hypercortisolism", "Primary hyperparathyroidism", "Primary microcephaly", "Primary peritoneal carcinoma", "Primitive neuroectodermal tumor", "Primitive reflex", "Productive cough", "Profound global developmental delay", "Profound hearing impairment", "Profound sensorineural hearing impairment", "Progeroid facial appearance", "Progressive", "Progressive cerebellar ataxia", "Progressive distal muscle weakness", "Progressive encephalopathy", "Progressive external ophthalmoplegia", "Progressive extrapyramidal movement disorder", "Progressive flexion contractures", "Progressive gait ataxia", "Progressive hearing impairment", "Progressive inability to walk", "Progressive leukoencephalopathy", "Progressive macrocephaly", "Progressive microcephaly", "Progressive muscle weakness", "Progressive neurologic deterioration", "Progressive night blindness", "Progressive peripheral neuropathy", "Progressive pes cavus", "Progressive proximal muscle weakness", "Progressive psychomotor deterioration", "Progressive pulmonary function impairment", "Progressive sensorineural hearing impairment", "Progressive spastic paraparesis", "Progressive spastic paraplegia", "Progressive spastic quadriplegia", "Progressive spasticity", "Progressive visual field defects", "Progressive visual loss", "Prolinuria", "Prolonged bleeding after dental extraction", "Prolonged bleeding after surgery", "Prolonged bleeding following circumcision", "Prolonged bleeding following procedure", "Prolonged bleeding time", "Prolonged neonatal jaundice", "Prolonged partial thromboplastin time", "Prolonged qtc interval", "Prominent antihelix", "Prominent antitragus", "Prominent calcaneus", "Prominent coccyx", "Prominent crus of helix", "Prominent digit pad", "Prominent ear helix", "Prominent eyelashes", "Prominent forehead", "Prominent metopic ridge", "Prominent nasal bridge", "Prominent nasal tip", "Prominent nasolabial fold", "Prominent nose", "Prominent occiput", "Prominent sternum", "Prominent superficial blood vessels", "Prominent supraorbital ridges", "Prominent umbilicus", "Prominent veins on trunk", "Proportionate short stature", "Proportionate tall stature", "Proptosis", "Prostate neoplasm", "Protein avoidance", "Protein losing enteropathy", "Protracted diarrhea", "Protruding ear", "Protruding tongue", "Protrusio acetabuli", "Protuberant abdomen", "Proximal amyotrophy", "Proximal femoral epiphysiolysis", "Proximal femoral metaphyseal abnormality", "Proximal femoral metaphyseal irregularity", "Proximal muscle weakness", "Proximal muscle weakness in lower limbs", "Proximal muscle weakness in upper limbs", "Proximal renal tubular acidosis", "Proximal symphalangism", "Proximal tubulopathy", "Proximal upper limb amyotrophy", "Pruritus", "Pseudoarthrosis", "Pseudobulbar paralysis", "Pseudobulbar signs", "Pseudoepiphyses", "Pseudoepiphyses of hand bones", "Pseudoepiphyses of the metacarpals", "Pseudohypoaldosteronism", "Pseudohypoparathyroidism", "Psoriasiform dermatitis", "Psychogenic non epileptic seizure", "Psychomotor deterioration", "Psychomotor retardation", "Psychosis", "Psychotic episodes", "Psychotic mentation", "Pterygium", "Ptosis", "Puberty and gonadal disorders", "Pulmonary artery atresia", "Pulmonary artery dilatation", "Pulmonary artery hypoplasia", "Pulmonary artery stenosis", "Pulmonary carcinoid tumor", "Pulmonary cyst", "Pulmonary edema", "Pulmonary embolism", "Pulmonary fibrosis", "Pulmonary hemorrhage", "Pulmonary hypoplasia", "Pulmonary infiltrates", "Pulmonary insufficiency", "Pulmonary interstitial high resolution computed tomography abnormality", "Pulmonary interstitial thickening", "Pulmonary venous hypertension", "Pulmonic stenosis", "Pulverulent cataract", "Punctate cataract", "Pure red cell aplasia", "Purpura", "Pustule", "Pyelonephritis", "Pyoderma gangrenosum", "Pyridoxine responsive sideroblastic anemia", "Quadriceps muscle weakness", "Radial bowing", "Radial deviation of the 2nd finger", "Radial deviation of the hand", "Radial deviation of the hand or of fingers of the hand", "Radioulnar dislocation", "Radioulnar synostosis", "Ragged red muscle fibers", "Rapidly progressive", "Raynaud phenomenon", "Reactive hypoglycemia", "Receptive language delay", "Rectal fistula", "Rectal prolapse", "Recurrent", "Recurrent abscess formation", "Recurrent acute respiratory tract infection", "Recurrent aspergillus infections", "Recurrent aspiration pneumonia", "Recurrent bacterial infections", "Recurrent bacterial skin infections", "Recurrent bronchitis", "Recurrent bronchopulmonary infections", "Recurrent corneal erosions", "Recurrent cutaneous abscess formation", "Recurrent ear infections", "Recurrent fever", "Recurrent fractures", "Recurrent gastroenteritis", "Recurrent hand flapping", "Recurrent herpes", "Recurrent hypoglycemia", "Recurrent infection of the gastrointestinal tract", "Recurrent joint dislocation", "Recurrent lower respiratory tract infections", "Recurrent mycobacterial infections", "Recurrent opportunistic infections", "Recurrent otitis media", "Recurrent pancreatitis", "Recurrent paroxysmal headache", "Recurrent pharyngitis", "Recurrent pneumonia", "Recurrent respiratory infections", "Recurrent sinopulmonary infections", "Recurrent sinusitis", "Recurrent skin infections", "Recurrent staphylococcal infections", "Recurrent staphylococcus aureus infections", "Recurrent tonsillitis", "Recurrent upper and lower respiratory tract infections", "Recurrent urinary tract infections", "Recurrent viral infections", "Red eye", "Red green dyschromatopsia", "Red hair", "Reduced antigen specific t cell proliferation", "Reduced antithrombin iii activity", "Reduced brain n acetyl aspartate level by mrs", "Reduced c peptide level", "Reduced circulating prolactin concentration", "Reduced consciousness confusion", "Reduced delayed hypersensitivity", "Reduced factor viii activity", "Reduced factor xi activity", "Reduced factor xii activity", "Reduced factor xiii activity", "Reduced forced expiratory volume in one second", "Reduced forced vital capacity", "Reduced natural killer cell count", "Reduced pancreatic beta cells", "Reduced protein c activity", "Reduced protein s activity", "Reduced renal corticomedullary differentiation", "Reduced sperm motility", "Reduced subcutaneous adipose tissue", "Reduced systolic function", "Reduced tendon reflexes", "Reduced visual acuity", "Reduced vital capacity", "Reduction of neutrophil motility", "Redundant neck skin", "Redundant skin", "Refractory anemia", "Regional abnormality of skin", "Relative macrocephaly", "Remnants of the hyaloid vascular system", "Renal agenesis", "Renal angiomyolipoma", "Renal cell carcinoma", "Renal cortical cysts", "Renal cortical microcysts", "Renal corticomedullary cysts", "Renal cyst", "Renal duplication", "Renal dysplasia", "Renal fanconi syndrome", "Renal fibrosis", "Renal hamartoma", "Renal hypoplasia", "Renal hypoplasia aplasia", "Renal insufficiency", "Renal magnesium wasting", "Renal malrotation", "Renal phosphate wasting", "Renal potassium wasting", "Renal salt wasting", "Renal steatosis", "Renal tubular acidosis", "Renal tubular atrophy", "Renal tubular dysfunction", "Renal tubular epithelial necrosis", "Renovascular hypertension", "Repetitive compulsive behavior", "Respiratory alkalosis", "Respiratory arrest", "Respiratory distress", "Respiratory failure", "Respiratory failure requiring assisted ventilation", "Respiratory insufficiency", "Respiratory insufficiency due to defective ciliary clearance", "Respiratory paralysis", "Respiratory tract infection", "Response to drugs acting on neuromuscular transmission", "Resting tremor", "Restless legs", "Restlessness", "Restrictive behavior", "Restrictive cardiomyopathy", "Restrictive ventilatory defect", "Reticular hyperpigmentation", "Reticulated skin pigmentation", "Reticulocytopenia", "Reticulocytosis", "Retinal arterial tortuosity", "Retinal arteriolar tortuosity", "Retinal atrophy", "Retinal coloboma", "Retinal degeneration", "Retinal detachment", "Retinal dysplasia", "Retinal dystrophy", "Retinal fold", "Retinal hamartoma", "Retinal hemorrhage", "Retinal neovascularization", "Retinal nonattachment", "Retinal perforation", "Retinal pigment epithelial atrophy", "Retinal pigment epithelial mottling", "Retinal telangiectasia", "Retinal thinning", "Retinal vascular tortuosity", "Retinopathy", "Retrocollis", "Retrognathia", "Rhabdomyolysis", "Rhabdomyosarcoma", "Rhegmatogenous retinal detachment", "Rheumatoid arthritis", "Rheumatoid factor positive", "Rhinitis", "Rhizomelia", "Rhizomelic arm shortening", "Rib fusion", "Rib segmentation abnormalities", "Rickets", "Ridged fingernail", "Ridged nail", "Rieger anomaly", "Right aortic arch with mirror image branching", "Right bundle branch block", "Right ventricular cardiomyopathy", "Right ventricular dilatation", "Right ventricular hypertrophy", "Rigidity", "Rimmed vacuoles", "Rod cone dystrophy", "Rotary nystagmus", "Round ear", "Round face", "Saccadic oscillation", "Saccadic smooth pursuit", "Sacrococcygeal teratoma", "Sagittal craniosynostosis", "Sandal gap", "Sarcoma", "Scaling skin", "Scanning speech", "Scaphocephaly", "Scapular winging", "Scarring", "Scarring alopecia of scalp", "Schistocytosis", "Schizencephaly", "Schizophrenia", "Schwannoma", "Scleral staphyloma", "Sclerocornea", "Scleroderma", "Sclerosis of hand bone", "Sclerosis of skull base", "Scotoma", "Scrotal hypoplasia", "Sea blue histiocytosis", "Seborrheic dermatitis", "Second degree atrioventricular block", "Secondary amenorrhea", "Secondary growth hormone deficiency", "Secondary microcephaly", "Secretory diarrhea", "Secundum atrial septal defect", "Segmental peripheral demyelination remyelination", "Selective tooth agenesis", "Self injurious behavior", "Self mutilation", "Semilobar holoprosencephaly", "Senile plaques", "Sensorimotor neuropathy", "Sensory ataxia", "Sensory axonal neuropathy", "Sensory neuropathy", "Sepsis", "Septate vagina", "Septic arthritis", "Septo optic dysplasia", "Serositis", "Severe b lymphocytopenia", "Severe combined immunodeficiency", "Severe cytomegalovirus infection", "Severe demyelination of the white matter", "Severe expressive language delay", "Severe failure to thrive", "Severe global developmental delay", "Severe hearing impairment", "Severe infection", "Severe intrauterine growth retardation", "Severe lactic acidosis", "Severe muscular hypotonia", "Severe photosensitivity", "Severe platyspondyly", "Severe postnatal growth retardation", "Severe short limb dwarfism", "Severe short stature", "Severe varicella zoster infection", "Severe viral infection", "Severely reduced visual acuity", "Shagreen patch", "Shallow acetabular fossae", "Shallow anterior chamber", "Shallow orbits", "Shawl scrotum", "Shield chest", "Shock", "Short 1st metacarpal", "Short attention span", "Short chin", "Short clavicles", "Short columella", "Short digit", "Short face", "Short femur", "Short foot", "Short fourth metatarsal", "Short lingual frenulum", "Short long bone", "Short lower limbs", "Short middle phalanx of finger", "Short middle phalanx of the 2nd finger", "Short middle phalanx of toe", "Short nail", "Short nose", "Short palm", "Short palpebral fissure", "Short phalanx of the thumb", "Short philtrum", "Short proximal phalanx of finger", "Short ribs", "Short stepped shuffling gait", "Short sternum", "Short term memory impairment", "Short thorax", "Short thumb", "Short tibia", "Short umbilical cord", "Short upper lip", "Shortened pr interval", "Shortened qt interval", "Shortening of all distal phalanges of the fingers", "Shortening of all middle phalanges of the fingers", "Shortening of all phalanges of the toes", "Shoulder dislocation", "Shoulder girdle muscle atrophy", "Shoulder girdle muscle weakness", "Shoulder pain", "Shuffling gait", "Shyness", "Sick sinus syndrome", "Sideroblastic anemia", "Simple ear", "Simple febrile seizure", "Simplified gyral pattern", "Single fiber emg abnormality", "Single naris", "Single transverse palmar crease", "Single ventricle", "Sinus bradycardia", "Sinus tachycardia", "Sirenomelia", "Skeletal dysplasia", "Skeletal muscle atrophy", "Skeletal muscle hypertrophy", "Skeletal myopathy", "Skin appendage neoplasm", "Skin dimple", "Skin erosion", "Skin nodule", "Skin picking", "Skin pit", "Skin plaque", "Skin rash", "Skin tags", "Skin ulcer", "Skin vesicle", "Skull asymmetry", "Slanting of the palpebral fissure", "Sleep apnea", "Sleep disturbance", "Sleep wake cycle disturbance", "Slender build", "Slender finger", "Slender long bone", "Slender toe", "Sloping forehead", "Slow decrease in visual acuity", "Slow pupillary light response", "Slow saccadic eye movements", "Slowly progressive", "Slurred speech", "Small anterior fontanelle", "Small basal ganglia", "Small cerebral cortex", "Small earlobe", "Small epiphyses", "Small face", "Small for gestational age", "Small hand", "Small intestinal dysmotility", "Small nail", "Small pituitary gland", "Small placenta", "Smooth muscle antibody positivity", "Smooth philtrum", "Snoring", "Social and occupational deterioration", "Soft doughy skin", "Soft skin", "Soft tissue neoplasm", "Soft tissue sarcoma", "Solitary median maxillary central incisor", "Somatic mosaicism", "Somatic mutation", "Somatic sensory dysfunction", "Sound sensitivity", "Sparse and thin eyebrow", "Sparse body hair", "Sparse eyebrow", "Sparse eyelashes", "Sparse hair", "Sparse lateral eyebrow", "Sparse or absent eyelashes", "Sparse scalp hair", "Spastic ataxia", "Spastic diplegia", "Spastic dysarthria", "Spastic gait", "Spastic hyperactive bladder", "Spastic paraparesis", "Spastic paraparetic gait", "Spastic paraplegia", "Spastic tetraparesis", "Spastic tetraplegia", "Spasticity", "Specific learning disability", "Speech apraxia", "Speech articulation difficulties", "Spider hemangioma", "Spina bifida", "Spina bifida occulta", "Spinal canal stenosis", "Spinal cord compression", "Spinal cord lesion", "Spinal cord tumor", "Spinal deformities", "Spinal muscular atrophy", "Spinal rigidity", "Spinocerebellar tract degeneration", "Splanchnic vein thrombosis", "Splenomegaly", "Split nail", "Spoken word recognition deficit", "Spondyloepimetaphyseal dysplasia", "Spondyloepiphyseal dysplasia", "Spondylolisthesis", "Spondylolysis", "Spontaneous abortion", "Spontaneous hemolytic crises", "Spontaneous pain sensation", "Spontaneous recurrent epistaxis", "Sporadic", "Spotty hyperpigmentation", "Spotty hypopigmentation", "Sprengel anomaly", "Squamous cell carcinoma", "Squamous cell carcinoma of the skin", "Square face", "Squared iliac bones", "St segment elevation", "Stage 5 chronic kidney disease", "Staring gaze", "Status epilepticus", "Status epilepticus with prominent motor symptoms", "Stenosis of the external auditory canal", "Steppage gait", "Stereotypical body rocking", "Stereotypical hand wringing", "Stereotypy", "Steroid resistant nephrotic syndrome", "Stiff skin", "Stillbirth", "Stomach cancer", "Stomatitis", "Stomatocytosis", "Stooped posture", "Streak ovary", "Striae distensae", "Stridor", "Stroke", "Stroke like episode", "Stuttering", "Subacute progressive viral hepatitis", "Subarachnoid hemorrhage", "Subcapsular cataract", "Subcortical band heterotopia", "Subcortical cerebral atrophy", "Subcortical heterotopia", "Subcutaneous hemorrhage", "Subcutaneous lipoma", "Subcutaneous nodule", "Subdural hemorrhage", "Subependymal cysts", "Subglottic stenosis", "Submucous cleft of soft and hard palate", "Submucous cleft soft palate", "Subretinal fluid", "Subsarcolemmal accumulations of abnormally shaped mitochondria", "Substantia nigra gliosis", "Subvalvular aortic stenosis", "Sudden death", "Sudden episodic apnea", "Sudden loss of visual acuity", "Suicidal ideation", "Sunken cheeks", "Supernumerary bones of the axial skeleton", "Supernumerary nipple", "Supernumerary spleens", "Supernumerary tooth", "Supernumerary vertebrae", "Supranuclear gaze palsy", "Supranuclear ophthalmoplegia", "Supravalvular aortic stenosis", "Supraventricular arrhythmia", "Supraventricular tachycardia", "Swan neck like deformities of the fingers", "Symphalangism affecting the phalanges of the hand", "Symphalangism of middle phalanx of finger", "Symptomatic seizures", "Syncope", "Syndactyly", "Synostosis involving bones of the hand", "Synostosis involving bones of the lower limbs", "Synostosis involving bones of the upper limbs", "Synostosis involving digits", "Synostosis of carpal bones", "Synostosis of carpals tarsals", "Synostosis of joints", "Synostosis of metacarpals metatarsals", "Synovitis", "Syringomyelia", "Systemic lupus erythematosus", "T cell lymphoma", "T lymphocytopenia", "Tachycardia", "Tachypnea", "Talipes calcaneovalgus", "Talipes equinovalgus", "Talipes equinovarus", "Talipes valgus", "Tall chin", "Tall stature", "Tapered distal phalanges of finger", "Tapered finger", "Tarsal synostosis", "Telangiectasia", "Telangiectasia of the skin", "Telecanthus", "Temperature instability", "Temporal cortical atrophy", "Temporal optic disc pallor", "Temporal pattern", "Tendon xanthomatosis", "Tented upper lip vermilion", "Teratoma", "Testicular adrenal rest tumor", "Testicular atrophy", "Testicular dysgenesis", "Tetany", "Tetralogy of fallot", "Tetraparesis", "Tetraplegia", "Tetraplegia tetraparesis", "Thenar muscle atrophy", "Thick cerebral cortex", "Thick corpus callosum", "Thick eyebrow", "Thick hair", "Thick lower lip vermilion", "Thick nasal alae", "Thick upper lip vermilion", "Thick vermilion border", "Thickened calvaria", "Thickened cortex of long bones", "Thickened ears", "Thickened helices", "Thickened nuchal skin fold", "Thickened ribs", "Thickened skin", "Thin bony cortex", "Thin clavicles", "Thin eyebrow", "Thin lower lip vermilion", "Thin nail", "Thin ribs", "Thin skin", "Thin upper lip vermilion", "Thin vermilion border", "Third degree atrioventricular block", "Thoracic aortic aneurysm", "Thoracic hypoplasia", "Thoracic kyphoscoliosis", "Thoracic kyphosis", "Thoracic scoliosis", "Thoracolumbar kyphoscoliosis", "Thoracolumbar kyphosis", "Thoracolumbar scoliosis", "Thrombocytosis", "Thromboembolism", "Thrombophlebitis", "Thymus hyperplasia", "Thyroid adenoma", "Thyroid carcinoma", "Thyroiditis", "Tibial bowing", "Tibial torsion", "Tibialis muscle weakness", "Tics", "Tiger tail banding", "Tinnitus", "Tip toe gait", "Tissue ischemia", "Titubation", "Toe clinodactyly", "Toe syndactyly", "Toe walking", "Toenail dysplasia", "Tongue atrophy", "Tongue fasciculations", "Tongue nodules", "Tongue thrusting", "Tonic seizure", "Tooth malposition", "Torsade de pointes", "Torsion dystonia", "Total anomalous pulmonary venous return", "Toxemia of pregnancy", "Tracheal stenosis", "Tracheobronchomalacia", "Tracheoesophageal fistula", "Tracheomalacia", "Tractional retinal detachment", "Transient global amnesia", "Transient ischemic attack", "Transient neonatal diabetes mellitus", "Transient neutropenia", "Transposition of the great arteries", "Tremor", "Tremor by anatomical site", "Triangular face", "Triangular mouth", "Triangular shaped phalanges of the hand", "Triceps weakness", "Trichorrhexis nodosa", "Tricuspid atresia", "Tricuspid stenosis", "Tricuspid valve prolapse", "Trigonocephaly", "Triphalangeal thumb", "Trismus", "Tritanomaly", "Trophic changes related to pain", "Truncal ataxia", "Truncal obesity", "Truncal titubation", "Truncus arteriosus", "Tube feeding", "Tubulointerstitial nephritis", "Turricephaly", "Type 1 fibers relatively smaller than type 2 fibers", "Type 1 muscle fiber atrophy", "Type 2 muscle fiber atrophy", "Type 2 muscle fiber predominance", "Type i diabetes mellitus", "Type i transferrin isoform profile", "Type ii diabetes mellitus", "Type ii lissencephaly", "Type ii transferrin isoform profile", "Typical absence seizure", "U shaped upper lip vermilion", "Ulcerative colitis", "Ulnar bowing", "Ulnar claw", "Ulnar deviation of finger", "Ulnar deviation of the 2nd finger", "Ulnar deviation of the hand", "Ulnar deviation of the hand or of fingers of the hand", "Ulnar deviation of the wrist", "Uncombable hair", "Unconjugated hyperbilirubinemia", "Underdeveloped nasal alae", "Underdeveloped supraorbital ridges", "Underdeveloped tragus", "Underfolded helix", "Undetectable electroretinogram", "Undetectable light and dark adapted electroretinogram", "Undetectable visual evoked potentials", "Unexplained fevers", "Unilateral primary pulmonary dysgenesis", "Unilateral ptosis", "Unilateral renal agenesis", "Unsteady gait", "Unusual fungal infection", "Unusual infection", "Unusual infection by anatomical site", "Unusual skin infection", "Upgaze palsy", "Uplifted earlobe", "Upper airway obstruction", "Upper extremity joint dislocation", "Upper eyelid coloboma", "Upper limb amyotrophy", "Upper limb asymmetry", "Upper limb hypertonia", "Upper limb muscle weakness", "Upper limb pain", "Upper limb postural tremor", "Upper limb spasticity", "Upper limb undergrowth", "Upper motor neuron dysfunction", "Upslanted palpebral fissure", "Ureteral duplication", "Ureteral obstruction", "Ureteral stenosis", "Ureterocele", "Ureteropelvic junction obstruction", "Urethral obstruction", "Urethral stenosis", "Urethral stricture", "Urethral valve", "Urethrovaginal fistula", "Uric acid nephrolithiasis", "Urinary bladder sphincter dysfunction", "Urinary glycosaminoglycan excretion", "Urinary incontinence", "Urinary retention", "Urinary tract neoplasm", "Urinary urgency", "Urogenital fistula", "Urogenital sinus anomaly", "Urticaria", "Uterine prolapse", "Uterus didelphys", "Uveal melanoma", "Uveitis", "Vacuolated lymphocytes", "Vaginal atresia", "Vaginal fistula", "Vaginal neoplasm", "Variable expressivity", "Varicose veins", "Vascular calcification", "Vascular dilatation", "Vascular neoplasm", "Vascular skin abnormality", "Vascular tortuosity", "Vasculitis", "Vegetative state", "Vein of galen aneurysmal malformation", "Velopharyngeal insufficiency", "Venous insufficiency", "Venous malformation", "Venous thrombosis", "Ventilator dependence with inability to wean", "Ventricular arrhythmia", "Ventricular escape rhythm", "Ventricular fibrillation", "Ventricular hypertrophy", "Ventricular preexcitation", "Ventricular septal hypertrophy", "Ventricular tachycardia", "Ventriculomegaly", "Verrucae", "Vertebral arch anomaly", "Vertebral clefting", "Vertebral compression fracture", "Vertebral fusion", "Vertebral hypoplasia", "Vertebral segmentation defect", "Vertebral wedging", "Vertical nystagmus", "Vertical supranuclear gaze palsy", "Vertigo", "Very long chain fatty acid accumulation", "Vestibular dysfunction", "Viral encephalitis", "Viral hepatitis", "Viral infection induced rhabdomyolysis", "Visceral angiomatosis", "Visual acuity test abnormality", "Visual agnosia", "Visual field defect", "Visual fixation instability", "Visual hallucinations", "Visual impairment", "Visual loss", "Vitamin b12 deficiency", "Vitiligo", "Vitreoretinopathy", "Vitreous floaters", "Vitreous hemorrhage", "Vitritis", "Vocal cord paralysis", "Vocal cord paresis", "Volvulus", "Vomiting", "Waddling gait", "Weak cry", "Weak voice", "Weakness due to upper motor neuron dysfunction", "Weakness of facial musculature", "Weakness of long finger extensor muscles", "Weakness of muscles of respiration", "Weakness of the intrinsic hand muscles", "Webbed neck", "Weight loss", "Wheezing", "White forelock", "White hair", "Wide anterior fontanel", "Wide cranial sutures", "Wide intermamillary distance", "Wide mouth", "Wide nasal bridge", "Wide nasal ridge", "Wide nose", "Wide pubic symphysis", "Widely patent fontanelles and sutures", "Widely spaced incisors", "Widely spaced teeth", "Widened cerebral subarachnoid space", "Widened subarachnoid space", "Widow s peak", "Woolly hair", "Wormian bones", "Wrist flexion contracture", "Writer s cramp", "X linked dominant inheritance", "X linked recessive inheritance", "Xanthelasma", "Xanthomatosis", "Xerostomia", "Y shaped metacarpals", "Yellow white lesions of the retina", "Young adult onset", "Zollinger ellison syndrome", "Zonular cataract"], "available_proteins": ["AAAS", "AAGAB", "AARS", "AARS2", "AASS", "ABCB1", "ABCB7", "ABCD3", "ABHD11", "ABHD12", "ACACA", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACO2", "ACOX1", "ACP2", "ACSF3", "ACSL4", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ADA", "ADAM17", "ADAR", "ADD1", "ADD3", "ADH5", "ADK", "ADNP", "ADPRHL2", "ADSL", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AKAP9", "AKT1", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALG1", "ALG13", "ANAPC1", "ANAPC2", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANXA11", "AP1B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "APC", "APPL1", "APRT", "ARCN1", "ARHGDIA", "ARHGEF2", "ARID1A", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARMC9", "ARPC1B", "ARVCF", "ASAH1", "ASCC1", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD3A", "ATIC", "ATL3", "ATP13A2", "ATP1A1", "ATP2A2", "ATP5A1", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "ATRX", "ATXN10", "ATXN2", "B3GALT6", "B4GALT1", "B4GAT1", "BAG3", "BANF1", "BAX", "BAZ1B", "BCAP31", "BCAT2", "BCOR", "BCS1L", "BICD2", "BLM", "BLVRA", "BMS1", "BPTF", "BRAT1", "BRCA1", "BRD4", "BUB1", "BUB1B", "BUB3", "BUD23", "C19orf70", "C1QBP", "C21orf59", "CAD", "CALD1", "CALM3", "CALR", "CAMK2G", "CAP2", "CAPN1", "CARS", "CASK", "CAST", "CBL", "CCDC22", "CCDC47", "CCDC88A", "CCT5", "CD2AP", "CD3EAP", "CDC42", "CDC45", "CDC73", "CDH2", "CDK4", "CDK5", "CDK6", "CDKN2A", "CENPE", "CEP250", "CEP55", "CFL2", "CHAMP1", "CHD1", "CHD4", "CHD8", "CHEK2", "CHMP1A", "CHMP2B", "CHMP4B", "CHORDC1", "CHP1", "CHST14", "CHUK", "CISD2", "CIZ1", "CLASP1", "CLCC1", "CLN5", "CLN6", "CLPB", "CLPP", "CLPX", "CLTC", "CNOT1", "CNOT3", "CNP", "COA3", "COA7", "COASY", "COG2", "COG4", "COG7", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COQ8A", "COX15", "COX2", "COX4I1", "COX5A", "CPNE1", "CPOX", "CPSF1", "CPT1A", "CPT2", "CRKL", "CRTAP", "CSNK2B", "CSTB", "CTBP1", "CTCF", "CTDP1", "CTH", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTSA", "CTSB", "CTSC", "CUL3", "CUL4B", "CWF19L1", "CYB5R3", "CYC1", "CYFIP2", "DARS", "DARS2", "DAXX", "DBT", "DCAF8", "DCPS", "DCTN1", "DCTN4", "DCXR", "DDB1", "DDOST", "DDRGK1", "DDX3X", "DDX41", "DDX6", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHODH", "DHPS", "DHX16", "DHX30", "DHX37", "DHX38", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIP2B", "DIS3L2", "DKC1", "DLAT", "DLD", "DLST", "DNA2", "DNAAF5", "DNAJB11", "DNAJC21", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DPF2", "DPM1", "DPP9", "DPYSL5", "DSC3", "DSG2", "DSP", "DST", "DYM", "DYNC1H1", "DYNC1I2", "DYNC2H1", "DYNLL1", "EARS2", "EBP", "ECE1", "ECHS1", "EDC3", "EEF1A2", "EEF2", "EFL1", "EFTUD2", "EGFR", "EGLN1", "EIF2AK2", "EIF2AK4", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF3F", "EIF4A3", "EIF4G1", "EIF4H", "EIF5A", "ELAC2", "ELP1", "ELP2", "ELP4", "EMC1", "EMD", "EMG1", "EPB41", "EPHX2", "EPRS", "EPS15L1", "ERAL1", "ERAP1", "ERCC2", "ERCC3", "ERGIC1", "ERLIN1", "ERLIN2", "ESS2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXOC2", "EXOC6B", "EXOC7", "EXOC8", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EXTL3", "EZR", "FAH", "FAM50A", "FANCA", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD2", "FDFT1", "FDPS", "FDXR", "FECH", "FH", "FHL1", "FIP1L1", "FKBP10", "FKBP14", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FMR1", "FOXRED1", "FSCN1", "FTO", "FUCA1", "FUS", "FXR1", "G6PD", "GAA", "GALK1", "GALM", "GALNT2", "GANAB", "GAPVD1", "GARS", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GCDH", "GDAP1", "GDAP2", "GDI1", "GEMIN4", "GEMIN5", "GFM1", "GFPT1", "GGCX", "GIGYF2", "GLA", "GLB1", "GLDC", "GLMN", "GLRX5", "GLS", "GLUD1", "GM2A", "GMPPA", "GMPPB", "GNA11", "GNAI2", "GNAI3", "GNE", "GNPAT", "GNS", "GOT2", "GPD2", "GPHN", "GPI", "GPKOW", "GPT2", "GRHPR", "GSDME", "GSR", "GSS", "GSTM3", "GTF2I", "GTPBP3", "GUSB", "GYG1", "GYS1", "H2AFY", "HADH", "HADHA", "HADHB", "HARS2", "HAX1", "HCCS", "HCFC1", "HELLS", "HEXA", "HEXB", "HEXIM1", "HIBCH", "HIST1H1E", "HK1", "HLA-A", "HLA-B", "HLA-C", "HMBS", "HMGA1", "HMGB3", "HMGCL", "HMMR", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HOXD13", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B4", "HSPA9", "HSPB1", "HSPD1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IER3IP1", "IFNGR1", "IFT27", "IFT88", "IGBP1", "IGF1R", "IGF2BP2", "IGF2R", "IKBKB", "IKBKG", "IMPA1", "IMPAD1", "IMPDH1", "INF2", "INTS1", "IRF2BPL", "IRS4", "ISCU", "ITCH", "ITPA", "IVD", "JAGN1", "JUP", "KARS", "KDM1A", "KDM3B", "KDSR", "KIAA0319L", "KIF11", "KIF14", "KIF15", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF4A", "KIF5C", "KIFBP", "KLC2", "KMT2A", "L2HGDH", "LAMB1", "LAMC1", "LAMP2", "LAMTOR2", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDHA", "LDLR", "LDLRAP1", "LEMD2", "LEMD3", "LETM1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMNA", "LMNB1", "LMNB2", "LONP1", "LRBA", "LRP1", "LRPAP1", "LRPPRC", "LSS", "LZTFL1", "MACF1", "MAD1L1", "MAGED2", "MAGT1", "MAN2B1", "MAP1B", "MAP2K1", "MAPK1", "MAPRE2", "MARS", "MAT2A", "MATR3", "MBOAT7", "MCCC1", "MCCC2", "MCM10", "MCM2", "MCM4", "MCM5", "MCM6", "MCM7", "MDH1", "MDH2", "MECP2", "MED23", "MFF", "MFN2", "MGME1", "MIA3", "MICU1", "MID1", "MIF", "MINPP1", "MIPEP", "MMAB", "MOGS", "MORC2", "MPG", "MPI", "MRE11", "MRPL12", "MRPL3", "MRPL44", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS28", "MRPS34", "MRPS35", "MRPS7", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTAP", "MTCH1", "MTHFD1", "MTHFS", "MTMR2", "MTOR", "MTPAP", "MTR", "MTX2", "MUT", "MVK", "MYH14", "MYH9", "MYO6", "NAA10", "NAA15", "NACC1", "NADK2", "NAGLU", "NANS", "NARS", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG2", "NCAPH", "NCDN", "NCSTN", "ND5", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA6", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NEFL", "NEK9", "NELFA", "NEMF", "NFKB1", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIPBL", "NNT", "NONO", "NOP56", "NPC1", "NPC2", "NPM1", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSUN2", "NT5C2", "NT5C3A", "NUBPL", "NUMA1", "NUP107", "NUP133", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP37", "NUP62", "NUP85", "NUP88", "NUP93", "NXN", "OAT", "OCRL", "OGDH", "OGT", "OPA1", "OPA3", "OSGEP", "OXCT1", "P3H1", "P4HA2", "P4HB", "PABPN1", "PAFAH1B1", "PAK1", "PALLD", "PARK7", "PARN", "PBRM1", "PC", "PCBD1", "PCCA", "PCCB", "PCK2", "PCNA", "PCNT", "PDCD6", "PDE6D", "PDHA1", "PDHB", "PDK3", "PDXK", "PEPD", "PEX14", "PEX19", "PEX5", "PFKM", "PFN1", "PGK1", "PGM1", "PGM3", "PHB", "PHF6", "PHF8", "PHGDH", "PHIP", "PI4KA", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIK3C2A", "PISD", "PITRM1", "PKN1", "PLAA", "PLCB3", "PLD3", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNP", "PNPLA6", "PNPLA8", "PNPO", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLE", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR3A", "PON2", "POP1", "POR", "PPA2", "PPIB", "PPIL1", "PPOX", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R5D", "PPP3CA", "PPT1", "PQBP1", "PRCC", "PREPL", "PRKACA", "PRKAR1A", "PRKCD", "PRKCSH", "PRKDC", "PRPF3", "PRPF31", "PRPF4", "PRPF6", "PRPF8", "PRPS1", "PSAP", "PSAT1", "PSMB4", "PSMC3", "PSMD12", "PSMG2", "PSPH", "PTCD3", "PTDSS1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PUF60", "PUM1", "PURA", "PUS1", "PUS7", "PXMP2", "PYCR1", "PYCR2", "PYGL", "QARS", "QDPR", "QRICH1", "QRSL1", "RAB11B", "RAB18", "RAB3GAP1", "RAB3GAP2", "RAB7A", "RAC1", "RAD21", "RAD50", "RALA", "RANBP2", "RANGRF", "RAPGEF2", "RARS", "RARS2", "RBM10", "RBM12", "RBM28", "RBM8A", "RBMX", "RDH11", "RDX", "RECQL4", "REPS1", "RFC1", "RFC2", "RHOA", "RINT1", "RIPK1", "RNASEH2A", "RNASEH2B", "RNASET2", "RP2", "RPL10", "RPL11", "RPL13", "RPL15", "RPL18", "RPL21", "RPL26", "RPL27", "RPL31", "RPL35", "RPL35A", "RPL5", "RPS10", "RPS14", "RPS15A", "RPS17", "RPS19", "RPS20", "RPS23", "RPS24", "RPS26", "RPS28", "RPS6KA3", "RPS7", "RPSA", "RRAS2", "RREB1", "RRM2B", "RTN2", "SACS", "SAMHD1", "SAR1B", "SARS", "SARS2", "SASS6", "SBDS", "SCAF1", "SCARB2", "SCO1", "SCO2", "SCP2", "SCYL2", "SDHA", "SDHB", "SEC23A", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SELENBP1", "SEPT9", "SERPINB6", "SERPINH1", "SET", "SF3B1", "SF3B4", "SFXN4", "SGPL1", "SH3GL1", "SH3PXD2B", "SHMT2", "SHOC2", "SIGMAR1", "SIN3A", "SKIV2L", "SLC12A2", "SLC16A1", "SLC19A1", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC27A4", "SLC9A3R1", "SLTM", "SMARCA4", "SMARCAD1", "SMARCB1", "SMARCC2", "SMARCE1", "SMC1A", "SMC3", "SMCHD1", "SMG8", "SMN1*", "SMPD4", "SMS", "SNAP29", "SNRNP200", "SNRPE", "SOAT1", "SON", "SORD", "SPART", "SPATA5", "SPECC1L", "SPEN", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQSTM1", "SRCAP", "SRP54", "SRP72", "SRSF2", "SSBP1", "SSR4", "STAG1", "STAG2", "STAMBP", "STARD7", "STAT1", "STAT3", "STK4", "STT3A", "STT3B", "STUB1", "STXBP2", "SUCLA2", "SUCLG1", "SUZ12", "SYNE1", "SYNE2", "TACO1", "TAF15", "TALDO1", "TAP1", "TARDBP", "TARS", "TARS2", "TBC1D2B", "TBC1D8B", "TBCD", "TBCE", "TBK1", "TBL1XR1", "TBL2", "TCOF1", "TDRD7", "TECR", "TELO2", "TERF2IP", "TFAM", "TFG", "TFRC", "THG1L", "THOC2", "THOC6", "TIA1", "TIMM50", "TIMM8A", "TIMMDC1", "TJP2", "TKFC", "TKT", "TMCO1", "TMEM126A", "TMEM126B", "TMEM165", "TMEM199", "TMEM43", "TMEM63A", "TMLHE", "TMPO", "TMPO", "TMTC3", "TMX2", "TNPO3", "TOE1", "TOMM40", "TOP2A", "TOR1AIP1", "TP53", "TPI1", "TPM1", "TPM3", "TPP1", "TPP2", "TRAPPC11", "TRAPPC4", "TRIM28", "TRIO", "TRIP12", "TRIP13", "TRMT1", "TRMT10C", "TRMU", "TSC2", "TSFM", "TSPYL1", "TSR2", "TTC19", "TTC37", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUFM", "TWNK", "TXN2", "UBA1", "UBA5", "UBE2T", "UBE3A", "UBE4A", "UBQLN2", "UBR1", "UBTF", "UFD1", "UFSP2", "UGDH", "UGP2", "UMPS", "UNC45A", "UPF3B", "UQCC2", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USMG5", "USP7", "USP9X", "VAC14", "VAMP7", "VAPB", "VARS1", "VARS2", "VCL", "VCP", "VIM", "VPS13A", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS51", "VPS53", "VRK1", "WARS", "WARS2", "WASHC5", "WBP11", "WDR1", "WDR26", "WDR36", "WDR4", "WDR45B", "WDR48", "WFS1", "WIPI2", "WNK1", "WRAP53", "XPNPEP3", "XRCC1", "YAP1", "YARS", "YARS2", "YEATS2", "YME1L1", "YWHAE", "YWHAG", "ZC3H14", "ZCCHC8", "ZFR", "ZMPSTE24", "ZPR1"], "leading_proteins": ["ABCB1", "ABHD12", "ACAT2", "ACBD5", "ACOX1", "ACTN2", "ACTN4", "ADAM17", "AGPS", "AIFM1", "AKAP9", "AKT1", "ALDH3A2", "ALG1", "ANAPC2", "ANKLE2", "AP1B1", "APC", "ARL2", "ARL6IP1", "ASAH1", "ASNA1", "ATP13A2", "ATP1A1", "ATP2A2", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A2", "ATP6V1B2", "ATXN10", "ATXN2", "B4GALT1", "B4GAT1", "BICD2", "BRAT1", "BUB1", "BUB1B", "C19orf70", "C21orf59", "CALM3", "CASK", "CCDC22", "CCDC47", "CCT5", "CDKN2A", "CENPE", "CHEK2", "CHMP1A", "CHST14", "CHUK", "CLCC1", "CLN5", "CLPP", "COA3", "COG4", "COLEC12", "COMT", "COQ8A", "COX15", "COX5A", "CPT2", "CRTAP", "CSNK2B", "CSTB", "CTNND1", "CTPS1", "CTSA", "CTSB", "CTSC", "CYFIP2", "DCAF8", "DCPS", "DDX3X", "DHCR24", "DHCR7", "DHFR", "DIABLO", "DIS3L2", "DLD", "DNA2", "DNM2", "DPP9", "DSC3", "DYM", "EBP", "ECE1", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF4H", "EMD", "ERAP1", 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sha256:f24e90fecb9df9f39f6e0a61cef0b4d7cbffaf0fa077a002ceb11b252dc3d641 +size 144105 diff --git a/msigdb_kegg/consensus.joblib b/msigdb_kegg/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..d1d469ced5798bd29dac0477451f7baaaa9e7a28 --- /dev/null +++ b/msigdb_kegg/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3d96339d929c666a67ecb43dcfc30950f8cdd481d4212be8da03ccec33c6fc02 +size 82716 diff --git a/msigdb_kegg/df_merge.tsv b/msigdb_kegg/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..6610e50ad60d3ebf2457b95326e9dfe39ca9fe0e --- /dev/null +++ b/msigdb_kegg/df_merge.tsv @@ -0,0 +1,9 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Lysosome 17 47 2.538470911727062 0.0111338057993024 21.740291262135923 48.609223300970875 0.8281821627988494 0.1302152537326229 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0.3258958759345889 0.0382139780569428 0.0155575631698287 0.0548237001435711 0.0144174128758978 0.120966113106861 +Metabolism of xenobiotics by cytochrome p450 2 10 2.2272394738422348 0.0259312732634131 2.2305825242718447 8.677184466019417 0.4162080538073979 0.4339520212351831 1.7688613666570594 0.8590827321798344 1.0192072203934597 0.2887521752792201 0.1338425639181934 0.0847528009868792 0.012905013470629 0.0088528623379573 0.0547354250806853 +Sphingolipid metabolism 7 12 2.036012137264609 0.041749136516646 5.672330097087379 11.759708737864075 0.9805985471070467 0.1821702203806468 2.452838935293596 1.3449033287601222 1.7625559835482287 0.2542774311591588 1.0 1.0 0.2166826538338764 0.0028897230126965 0.0001416051152665 +Drug metabolism cytochrome p450 1 9 2.026308636870559 0.0427331667441337 2.7985436893203883 7.686893203883495 -0.1627781054424288 0.4867308326976521 1.8250409798654743 0.8456186672148164 0.9765503819502462 0.2910697006720338 0.1198919526526125 0.0756950383436983 0.144637307685789 0.0565188023636715 0.1824124195300006 +Porphyrin and chlorophyll metabolism 2 15 2.003293769790116 0.0451457658265253 3.728155339805826 13.315533980582524 1.2215621624941897 0.2689555702886888 1.770547470360957 1.4201912411596824 1.0389071586082248 0.2908939383930566 0.0107949235467619 0.0937235599037543 0.0158256043387446 0.0119341177484456 0.0145952588649919 diff --git a/msigdb_kegg/metrics.json b/msigdb_kegg/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..64c9ae2d5779e3a9c451e73391e2c76cbb6fae78 --- /dev/null +++ b/msigdb_kegg/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3329, + "annotations_size": 180, + "title": "Average number of proteins per term", + "value": 17.75 +} \ No newline at end of file diff --git a/msigdb_kegg/paths.json b/msigdb_kegg/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..cbad34ec9b20b805487b2e638916149d25fd6e11 --- /dev/null +++ b/msigdb_kegg/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_kegg/fragment/C342/C342_val_log2fc"} \ No newline at end of file diff --git a/msigdb_kegg/result.tsv b/msigdb_kegg/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..065133ab9f7e8005bcc84b8e60acc2dbb1fad76e --- /dev/null +++ b/msigdb_kegg/result.tsv @@ -0,0 +1,67 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Lysosome 0.551413870176844 2.538470911727062 0.0111338057993024 0.8667229318272603 0.2936477414156758 47 P50897,Q93050,P17900,Q99523,P20645,O15118,P07602,Q9UMR5,P07858,Q9Y487,O75503,Q8NCC3,P10619,P06280,Q13510,Q14108,P04062 17 +Glutathione metabolism 0.6452881526157538 2.4823742932513926 0.0130510107295855 0.9060174570993484 0.2936477414156758 24 O15217,P78417,Q9UJ14,O75874,P48735,Q7LG56 6 +Steroid biosynthesis 0.7674700172871186 2.2508109633243394 0.0243975128664211 0.988274758819756 0.333402084815312 11 Q16850,Q15125,P37268,P48449,Q15392,Q15800 6 +Vibrio cholerae infection 0.6299965448746728 2.2411449693606076 0.0250166861082965 0.989540932524833 0.333402084815312 20 O43731,Q9Y487,P24390 3 +Metabolism of xenobiotics by cytochrome p450 0.770282513480209 2.2272394738422348 0.0259312732634131 0.99116659719165 0.333402084815312 10 P07099,O15217 2 +Sphingolipid metabolism 0.7004948197476748 2.036012137264609 0.041749136516646 0.9995362761116786 0.4273316674413374 12 Q16739,Q06136,P06280,O95470,Q13510,O15270,P04062 7 +Drug metabolism cytochrome p450 0.7340838609349585 2.026308636870559 0.0427331667441337 0.9996145729730894 0.4273316674413374 9 O15217 1 +Porphyrin and chlorophyll metabolism 0.6393675286454384 2.003293769790116 0.0451457658265253 0.9997552773952588 0.4276967288828712 15 P30519,P09601 2 +Nicotinate and nicotinamide metabolism 0.8249029060365297 1.927529150619761 0.0539137187985065 0.999953491310606 0.4621175897014851 6 Q9BQG2,P43490 2 +Proteasome 0.5066709043171141 1.8533448878732657 0.0638329411865461 0.9999930240401204 0.522269518799014 36 P28070,P25786,P20618,P28074,P49721,P28072 6 +Peroxisome 0.5036561256039219 1.7552740092771224 0.0792124499496176 0.9999996462479678 0.5940933746221322 33 O75874,Q9NR77,Q15067,P48735,Q9BQG2 5 +Glycerophospholipid metabolism 0.5887210306693359 1.6692415548356825 0.095069517754124 0.9999999844854512 0.6366582270417852 14 P48651,Q96N66,P43304,Q8NCC3,O15228,P35790,O95674 7 +Folate biosynthesis 0.86573629659795 1.5997831655642651 0.1096466946571963 0.999999999165882 0.6366582270417852 4 P00374,P35270 2 +Renin angiotensin system 0.8409515974816114 1.5044086617657966 0.1324761753789032 0.999999999992226 0.6813060448057879 4 P10619,Q9UIQ6 2 +Cardiac muscle contraction 0.4995416219085704 1.4731825374769676 0.1407018224149681 0.9999999999986008 0.7035091120748405 22 P06753,P67936,P20674,P09493,P16615,Q9UDW1,P14406,O14949 8 +Hypertrophic cardiomyopathy hcm 0.5995435049204041 1.4079244252151326 0.1591534496537154 0.999999999999972 0.7430097342883948 10 P67936,P16615,P50402,P09493 4 +Autoimmune thyroid disease 0.8108270676691741 1.3880780677163784 0.1651132742863099 0.9999999999999922 0.7430097342883948 4 P49327,P04439,P10321 3 +Graft versus host disease 0.8108270676691741 1.3880780677163784 0.1651132742863099 0.9999999999999922 0.7430097342883948 4 P49327,P04439,P10321 3 +Allograft rejection 0.8108270676691741 1.3880780677163784 0.1651132742863099 0.9999999999999922 0.7430097342883948 4 P49327,P04439,P10321 3 +Parkinsons disease 0.4048461101169736 1.349029437651092 0.177327510910396 0.9999999999999994 0.7596898241443011 58 P21796,O43676,P45880,P20674,P12235,Q9UDW1,O75306,O75438,P00846,P14406,O14949 11 +Calcium signaling pathway 0.4839932091907565 1.320758069264472 0.1865820449203252 1.0 0.7596898241443011 20 P21796,P45880,P12235,P16615,P0DP25 5 +Oxidative phosphorylation 0.3929486406416715 1.2918550099791322 0.1964073606678384 1.0 0.7596898241443011 63 O43676,Q93050,P20674,O75964,Q9Y6M9,Q9UDW1,O75306,O75438,O95168,Q9Y487,Q86Y39,P00846,P14406,O14949 14 +Glycosaminoglycan biosynthesis keratan sulfate 0.8373910429816522 1.2862281368293011 0.198363454082123 1.0 0.7596898241443011 2 O43505 1 +Glycosphingolipid biosynthesis lacto and neolacto series 0.8373910429816522 1.2862281368293011 0.198363454082123 1.0 0.7596898241443011 2 O43505 1 +Steroid hormone biosynthesis 0.8295761947700644 1.2543229791235575 0.2097246349078301 1.0 0.7793375296724695 2 P21964 1 +Snare interactions in vesicular transport 0.5166258969637412 1.164732562483949 0.2441272638959613 1.0 0.8311627247481165 13 Q86Y82,Q9P2W9,O15400,O43752,O95721 5 +Huntingtons disease 0.358387561017266 1.0347374181363975 0.300791556309548 1.0 0.901959585322368 82 P21796,P45880,O43676,P19388,P20674,P42858,P12235,Q9Y6M9,Q9UDW1,O75306,O75438,O95168,Q13561,P00846,P14406,O14949 16 +One carbon pool by folate 0.5172413795477853 1.013806761560258 0.3106749682777046 1.0 0.901959585322368 11 P00374,P34896 2 +Dilated cardiomyopathy 0.5376493091840197 0.995175213289021 0.3196510548449272 1.0 0.9132887281283634 8 P67936,P16615,P50402,P09493 4 +Other glycan degradation 0.5517361865717769 0.9161062078985616 0.3596111921020664 1.0 0.9564379730955692 7 P04062 1 +Antigen processing and presentation 0.4321748535785588 0.9128508084969718 0.3613210120583261 1.0 0.9564379730955692 18 P10321,Q03518,P07858,P04439,P01889 5 +Natural killer cell mediated cytotoxicity 0.4298074087843323 0.8976336678584372 0.3693808835838945 1.0 0.963602305001464 18 P62993,P10321,P49327,P15260,P04439,P28482,P42574 7 +O glycan biosynthesis 0.6744324151263548 0.8655086264131893 0.3867596832675337 1.0 0.9675655102560456 4 O43505 1 +Glycosaminoglycan biosynthesis heparan sulfate 0.7452671911545943 0.8220884062253868 0.4110265834419047 1.0 0.9675655102560456 3 O43909 1 +Type i diabetes mellitus 0.5741095846922677 0.7848082473463197 0.4325660038658523 1.0 0.9675655102560456 5 P49327,P04439,P10321 3 +Fc epsilon ri signaling pathway 0.4760803266499959 0.7842067329251354 0.4329188150945549 1.0 0.9675655102560456 10 P31749,P28482 2 +Alzheimers disease 0.3369172576842604 0.7389821717533211 0.4599178232313832 1.0 0.9675655102560456 66 O43676,P78536,P20674,P49327,P28482,Q9Y6M9,P16615,Q9UDW1,O75306,O75438,O95168,Q00535,P00846,P14406,P42574,O14949 16 +Protein export 0.41778760468174 0.7121601182657983 0.4763656301367724 1.0 0.97438424346158 15 P09132,Q15070,P67812 3 +Biosynthesis of unsaturated fatty acids 0.4684287972285563 0.6668733292931102 0.5048530482623317 1.0 1.0 8 Q9NZ01,Q15067 2 +Abc transporters 0.5347320263376567 0.630981527554579 0.5280526027815833 1.0 1.0 5 Q03518 1 +Tgf beta signaling pathway 0.4441182027949325 0.6252794568964791 0.5317876604247913 1.0 1.0 10 P30154,P30153 2 +Mismatch repair 0.37245016678518 0.5683987005400836 0.5697642725924981 1.0 1.0 19 Q9UQ84,Q04837,P41440 3 +Endometrial cancer 0.3923156368846378 0.4792395725930197 0.6317682050314066 1.0 1.0 13 P31749,Q9UJX6,P28482 3 +Apoptosis 0.3453694214886182 0.4231920655804439 0.6721551352851796 1.0 1.0 22 O94919,Q13546,O95831,P31749,P49327,P42574,O15111 7 +Mtor signaling pathway 0.3520050420035892 0.3581800165410316 0.720208601010335 1.0 1.0 16 P31749,P06730 2 +Basal cell carcinoma 0.4344369426357839 0.3378521971583596 0.7354745725755334 1.0 1.0 6 Q9UJX6 1 +Citrate cycle tca cycle 0.3234734142612007 0.3124572232813085 0.7546930676462589 1.0 1.0 25 P48735 1 +P53 signaling pathway 0.3401269499190632 0.2930644093758059 0.7694729201795272 1.0 1.0 16 O14757,P42771,P49327,P31350,P42574,Q7LG56 6 +Non small cell lung cancer 0.3630184629664608 0.2900490799439137 0.7717786902821213 1.0 1.0 12 P62993,Q13043,P31749,P42771,P28482 5 +Jak stat signaling pathway 0.379301420931089 0.2803529779434126 0.7792067091559693 1.0 1.0 8 P31749,P62993,Q92783 3 +Colorectal cancer 0.3162295892083274 0.1847989229299113 0.8533867526868657 1.0 1.0 17 P31749,Q9UJX6,P28482 3 +Viral myocarditis 0.3421340541267701 0.1726060897754216 0.8629610648016262 1.0 1.0 11 P04439,P42574,P10321 3 +Prion diseases 0.3522168506085283 0.1325568864656301 0.8945438310470286 1.0 1.0 7 P11047 1 +Cytokine cytokine receptor interaction 0.423472814025212 0.1291836702705581 0.8972123171695383 1.0 1.0 4 P49327 1 +Type ii diabetes mellitus 0.3306194742914741 0.1257811910575811 0.8999051308745616 1.0 1.0 9 O14654,P28482,P52789 3 +Phosphatidylinositol signaling system 0.3042583566281956 0.1015620482230848 0.9191043047584916 1.0 1.0 15 P42356,Q9UBF8,O95674 3 +Dorso ventral axis formation 0.3538478863808304 0.0917159806762525 0.9269237001647984 1.0 1.0 5 P28482 1 +Cell adhesion molecules cams 0.318229905576205 0.0838076448059575 0.9332093697302956 1.0 1.0 10 P04439,P10586,P10321 3 +Long term depression 0.3127071419530652 0.0805948697431597 0.9357641462858824 1.0 1.0 12 P30154,P30153 2 +Dna replication 0.2851338734758691 0.0719170180941056 0.9426679466374313 1.0 1.0 33 Q04837,Q9Y2S7,Q9NR33,Q14181,P41440,P51530 6 +Glycine serine and threonine metabolism 0.314217110990891 0.0714451230524609 0.9430434983362408 1.0 1.0 9 P34896 1 +Glycosylphosphatidylinositol gpi anchor biosynthesis 0.3302790384737875 0.053590249418801 0.957261625186358 1.0 1.0 5 Q9Y2B2 1 +Acute myeloid leukemia 0.3041038884798038 0.0499268745339961 0.9601806612235232 1.0 1.0 12 P31749,P62993,P28482 3 +Retinol metabolism 0.3548872180451169 0.0459219495605426 0.9633724594108616 1.0 1.0 4 O94788,Q9BTZ2,Q8TC12 3 +Nucleotide excision repair 0.2763917211680479 0.0229941939706381 0.9816549042664158 1.0 1.0 25 Q9NR33,P54725,P41440 3 +Nitrogen metabolism 0.224962406015042 0.0029334316190115 0.9976594635577478 1.0 1.0 4 P32929,P08243,P00367 3 diff --git a/msigdb_kegg/selections.json b/msigdb_kegg/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..5ffda82838bf9350f75c98a9b733494f3c06a305 --- /dev/null +++ b/msigdb_kegg/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Abc transporters", "Acute myeloid leukemia", "Adherens junction", "Adipocytokine signaling pathway", "Alanine aspartate and glutamate metabolism", "Aldosterone regulated sodium reabsorption", "Allograft rejection", "Alpha linolenic acid metabolism", "Alzheimers disease", "Amino sugar and nucleotide sugar metabolism", "Aminoacyl trna biosynthesis", "Amyotrophic lateral sclerosis als", "Antigen processing and presentation", "Apoptosis", "Arachidonic acid metabolism", "Arginine and proline metabolism", "Arrhythmogenic right ventricular cardiomyopathy arvc", "Ascorbate and aldarate metabolism", "Autoimmune thyroid disease", "Axon guidance", "B cell receptor signaling pathway", "Basal cell carcinoma", "Basal transcription factors", "Base excision repair", "Beta alanine metabolism", "Biosynthesis of unsaturated fatty acids", "Bladder cancer", "Butanoate metabolism", "Calcium signaling pathway", "Cardiac muscle contraction", "Cell adhesion molecules cams", "Cell cycle", "Chemokine signaling pathway", "Chronic myeloid leukemia", "Citrate cycle tca cycle", "Colorectal cancer", "Cysteine and methionine metabolism", "Cytokine cytokine receptor interaction", "Cytosolic dna sensing pathway", "Dilated cardiomyopathy", "Dna replication", "Dorso ventral axis formation", "Drug metabolism cytochrome p450", "Drug metabolism other enzymes", "Ecm receptor interaction", "Endocytosis", "Endometrial cancer", "Epithelial cell signaling in helicobacter pylori infection", "Erbb signaling pathway", "Ether lipid metabolism", "Fatty acid metabolism", "Fc epsilon ri signaling pathway", "Fc gamma r mediated phagocytosis", "Focal adhesion", "Folate biosynthesis", "Fructose and mannose metabolism", "Galactose metabolism", "Gap junction", "Glioma", "Glutathione metabolism", "Glycerolipid metabolism", "Glycerophospholipid metabolism", "Glycine serine and threonine metabolism", "Glycolysis gluconeogenesis", "Glycosaminoglycan biosynthesis chondroitin sulfate", "Glycosaminoglycan biosynthesis heparan sulfate", "Glycosaminoglycan biosynthesis keratan sulfate", "Glycosaminoglycan degradation", "Glycosphingolipid biosynthesis ganglio series", "Glycosphingolipid biosynthesis globo series", "Glycosphingolipid biosynthesis lacto and neolacto series", "Glycosylphosphatidylinositol gpi anchor biosynthesis", "Glyoxylate and dicarboxylate metabolism", "Gnrh signaling pathway", "Graft versus host disease", "Hedgehog signaling pathway", "Hematopoietic cell lineage", "Histidine metabolism", "Homologous recombination", "Huntingtons disease", "Hypertrophic cardiomyopathy hcm", "Inositol phosphate metabolism", "Insulin signaling pathway", "Jak stat signaling pathway", "Leishmania infection", "Leukocyte transendothelial migration", "Limonene and pinene degradation", "Long term depression", "Long term potentiation", "Lysine degradation", "Lysosome", "Mapk signaling pathway", "Melanogenesis", "Melanoma", "Metabolism of xenobiotics by cytochrome p450", "Mismatch repair", "Mtor signaling pathway", "N glycan biosynthesis", "Natural killer cell mediated cytotoxicity", "Neuroactive ligand receptor interaction", "Neurotrophin signaling pathway", "Nicotinate and nicotinamide metabolism", "Nitrogen metabolism", "Nod like receptor signaling pathway", "Non homologous end joining", "Non small cell lung cancer", "Notch signaling pathway", "Nucleotide excision repair", "O glycan biosynthesis", "Olfactory transduction", "One carbon pool by folate", "Oocyte meiosis", "Other glycan degradation", "Oxidative phosphorylation", "P53 signaling pathway", "Pancreatic cancer", "Pantothenate and coa biosynthesis", "Parkinsons disease", "Pathogenic escherichia coli infection", "Pathways in cancer", "Pentose and glucuronate interconversions", "Pentose phosphate pathway", "Peroxisome", "Phenylalanine metabolism", "Phosphatidylinositol signaling system", "Porphyrin and chlorophyll metabolism", "Ppar signaling pathway", "Primary bile acid biosynthesis", "Primary immunodeficiency", "Prion diseases", "Progesterone mediated oocyte maturation", "Propanoate metabolism", "Prostate cancer", "Proteasome", "Protein export", "Proximal tubule bicarbonate reclamation", "Purine metabolism", "Pyrimidine metabolism", "Pyruvate metabolism", "Regulation of actin cytoskeleton", "Regulation of autophagy", "Renal cell carcinoma", "Renin angiotensin system", "Retinol metabolism", "Riboflavin metabolism", "Ribosome", "Rig i like receptor signaling pathway", "Rna degradation", "Rna polymerase", "Selenoamino acid metabolism", "Small cell lung cancer", "Snare interactions in vesicular transport", "Sphingolipid metabolism", "Spliceosome", "Starch and sucrose metabolism", "Steroid biosynthesis", "Steroid hormone biosynthesis", "Sulfur metabolism", "Systemic lupus erythematosus", "T cell receptor signaling pathway", "Taste transduction", "Taurine and hypotaurine metabolism", "Terpenoid backbone biosynthesis", "Tgf beta signaling pathway", "Thyroid cancer", "Tight junction", "Toll like receptor signaling pathway", "Tryptophan metabolism", "Type i diabetes mellitus", "Type ii diabetes mellitus", "Tyrosine metabolism", "Ubiquitin mediated proteolysis", "Valine leucine and isoleucine biosynthesis", "Valine leucine and isoleucine degradation", "Vascular smooth muscle contraction", "Vasopressin regulated water reabsorption", "Vegf signaling pathway", "Vibrio cholerae infection", "Viral myocarditis", "Wnt signaling pathway"], "available_proteins": ["AACS", "AARS", "AARS2", "AASDHPPT", "AASS", "ABCB1", "ABCB7", "ABCC4", "ABCD3", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOX1", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTN1", "ACTN2", "ACTN4", "ADA", "ADAM17", "ADAR", "ADH5", "ADI1", "ADK", "ADSL", "ADSS", "AFDN", "AGK", "AGL", "AGPS", "AHCY", "AHCYL1", "AIFM1", "AK1", "AK2", "AK3", "AK4", "AKR1A1", "AKR1B1", "AKT1", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG13", "ALG5", "ALYREF", "ANAPC1", "ANAPC2", "ANAPC5", "ANAPC7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APC", "APEX1", "APPL1", "APRT", "AQR", "ARF6", "ARFGAP1", "ARFGAP3", "ARHGAP35", "ARHGAP5", "ARHGDIA", "ARHGEF2", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASNA1", "ASNS", "ATG3", "ATG4B", "ATIC", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATRX", "B3GALT6", "B4GALT1", "B4GAT1", "BAIAP2", "BAX", "BCAS2", "BCAT2", "BDH2", "BIRC6", "BLM", "BLVRA", "BLVRB", "BNIP1", "BPNT1", "BRCA1", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "CAB39", "CACYBP", "CAD", "CADM1", "CALD1", "CALM3", "CALR", "CAMK2G", "CANX", "CAPN1", "CAPN2", "CARS", "CASK", "CASP3", "CBL", "CBR1", "CCDC6", "CCNA2", "CCNB1", "CD47", "CDC23", "CDC25C", "CDC27", "CDC42", "CDC45", "CDC5L", "CDH2", "CDIPT", "CDK1", "CDK4", "CDK5", "CDK6", "CDKN2A", "CDS2", "CETN2", "CFL1", "CFL2", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHKA", "CHMP2A", "CHMP2B", "CHMP3", "CHMP4A", "CHMP4B", "CHMP5", "CHORDC1", "CHP1", "CHST14", "CHUK", "CKB", "CKMT1A*", "CLN5", "CLTA", "CLTC", "CMAS", "CMPK1", "CNOT1", "CNOT3", "CNOT7", "CNOT9", "COASY", "COMT", "COX11", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPOX", "CPT1A", "CPT2", "CRK", "CRKL", "CRNKL1", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CTBP1", "CTBP2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC15", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DARS", "DARS2", "DAXX", "DBT", "DCP1A", "DCP1B", "DCP2", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN4", "DCXR", "DDB1", "DDOST", "DDX23", "DDX39B", "DDX3X", "DDX42", "DDX46", "DDX5", "DDX6", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHODH", "DHRS4", "DHX15", "DHX16", "DHX38", "DHX8", "DIAPH1", "DIAPH3", "DIS3", "DLAT", "DLD", "DLST", "DNA2", "DNM1L", "DNM2", "DNMT1", "DOLPP1", "DPM1", "DPYSL2", "DPYSL5", "DSG2", "DSP", "DTYMK", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBP", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EEA1", "EFTUD2", "EGFR", "EGLN1", "EHD1", "EHD4", "EHMT2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "ELOB", "ELOC", "EMD", "ENAH", "ENDOD1", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPHX1", "EPHX2", "EPN1", "EPRS", "EPS15", "ERBIN", "ERCC2", "ERCC3", "ERO1A", "EXO1", "EXOC3", "EXOC4", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXTL3", "EZR", "F11R", "FABP5", "FAH", "FAR1", "FARSA", "FARSB", "FASN", "FAU", "FDFT1", "FDPS", "FECH", "FEN1", "FH", "FLAD1", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FUCA1", "FUCA2", "G6PD", "GAA", "GABARAPL2", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GARS", "GART", "GBA", "GBE1", "GCAT", "GCDH", "GCLM", "GFPT1", "GGA1", "GGCT", "GGH", "GGT7", "GLA", "GLB1", "GLDC", "GLG1", "GLO1", "GLS", "GLUD1", "GM2A", "GMDS", "GMPPA", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNE", "GNG5", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOT1", "GOT2", "GPAM", "GPD2", "GPI", "GPT2", "GRB2", "GRHPR", "GSK3A", "GSK3B", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTSE1", "GUSB", "GYS1", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADH", "HADHA", "HADHB", "HAGH", "HARS2", "HCCS", "HDAC1", "HDAC2", "HERC4", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HIP1", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HMBS", "HMGB1", "HMGCL", "HMGCS1", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA3", "HNRNPC", "HNRNPK", "HNRNPM", "HNRNPU", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA1B", "HSPA2", "HSPA4", "HSPA6", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HTT", "HUWE1", "IARS", "IARS2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFNGR1", "IGF1R", "IGF2BP1", "IGF2R", "IKBKB", "IKBKG", "ILK", "IMPA1", "IMPDH1", "IMPDH2", "INPP4A", "IQGAP1", "IQGAP2", "IRS4", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "IVD", "JUP", "KARS", "KDELR1", "KDELR3", "KDSR", "L2HGDH", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAP3", "LARS", "LARS2", "LCMT1", "LDHA", "LDHB", "LDLR", "LDLRAP1", "LIG1", "LIG3", "LIPA", "LLGL1", "LMNA", "LNPEP", "LPCAT1", "LPGAT1", "LRP1", "LSM2", "LSM6", "LSS", "LTA4H", "LYPLA1", "M6PR", "MAD1L1", "MAGED1", "MAN1A2", "MAN2A1", "MAN2B1", "MAP2K1", "MAP2K3", "MAPK1", "MAPK14", "MAPK3", "MARCKS", "MARS", "MAT2A", "MAT2B", "MAVS", "MBOAT7", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MDH1", "MDH2", "ME2", "MGAT1", "MGST2", "MGST3", "MID1", "MIF", "MINPP1", "MMAB", "MOGS", "MPG", "MPHOSPH6", "MPI", "MPST", "MRE11", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTAP", "MTCH1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTMR2", "MTOR", "MTR", "MUT", "MVK", "MYH10", "MYH14", "MYH9", "MYL6", "NAA16", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NARS", "NBN", "NCBP1", "NCKAP1", "NCL", "NCSTN", "ND5", "NDUFA10", "NDUFA11", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFB1", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEFL", "NEFM", "NFKB1", "NIT2", "NLN", "NME1", "NME2", "NME3", "NNT", "NPC1", "NPC2", "NSD1", "NSD2", "NSDHL", "NSF", "NT5C2", "NT5C3A", "NUDT12", "NUDT5", "NUDT9", "OAT", "OCRL", "OGDH", "ORC3", "ORC5", "OXA1L", "OXCT1", "P4HA1", "P4HA2", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAK1", "PAK2", "PAK4", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PATL1", "PC", "PCBP1", "PCCA", "PCCB", "PCK2", "PCNA", "PDCD6", "PDCD6IP", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PECR", "PEX14", "PEX19", "PEX5", "PFAS", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PHF5A", "PHGDH", "PI4KA", "PI4KB", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIK3C2A", "PIK3C3", "PIK3R4", "PIN1", "PIP4K2B", "PISD", "PKM", "PKN1", "PLA2G15", "PLCB3", "PLCG1", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PMPCA", "PMVK", "PNP", "PNPT1", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "PPA1", "PPA2", "PPAT", "PPID", "PPIE", "PPIH", "PPIL1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP5C", "PPT1", "PPT2", "PQBP1", "PRDX5", "PRDX6", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKAR2B", "PRKCD", "PRKDC", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PSAP", "PSAT1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSPH", "PTDSS1", "PTGES2", "PTPN1", "PTPN11", "PTPRF", "PUF60", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "RAB11B", "RAB13", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RABEP1", "RAC1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RALA", "RAPGEF2", "RARS", "RARS2", "RBM17", "RBM22", "RBM25", "RBM8A", "RBMX", "RDH11", "RDX", "REXO2", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHEB", "RHOA", "RIPK1", "RNASEH2A", "RNASEH2B", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RRAS2", "RRM1", "RRM2", "RRM2B", "RSL24D1", "RUFY1", "RUVBL1", "SAE1", "SARS", "SARS2", "SART1", "SCARB2", "SCD", "SCP2", "SDHA", "SDHB", "SEC11A", "SEC22B", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEPHS1", "SETD7", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SGPL1", "SH3GL1", "SH3GLB1", "SHMT1", "SHMT2", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC19A1", "SLC25A10", "SLC25A15", "SLC25A17", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC38A2", "SLIT2", "SLK", "SLTM", "SLU7", "SMAP1", "SMAP2", "SMC1A", "SMC3", "SMNDC1", "SMPD4", "SMS", "SNAP23", "SNAP29", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SOAT1", "SOD2", "SORD", "SORT1", "SPCS2", "SPHK2", "SPR", "SPTAN1", "SPTLC1", "SPTLC2", "SQLE", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPRA", "SRPRB", "SRSF1", "SRSF10", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "STAG1", "STAG2", "STAM", "STAMBP", "STAT1", "STAT3", "STIP1", "STK4", "STMN1", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX4", "STX6", "STX7", "STX8", "SUCLA2", "SUCLG1", "SUCLG2", "SUGT1", "SYMPK", "TAB1", "TALDO1", "TAP1", "TARS", "TARS2", "TARSL2", "TBK1", "TBL1XR1", "TCERG1", "TECR", "TFAM", "TFG", "TFRC", "THOC1", "THOC2", "THOC3", "THOP1", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLN1", "TMLHE", "TOLLIP", "TOMM40", "TP53", "TPI1", "TPM1", "TPM3", "TPM4", "TPMT", "TPP1", "TPR", "TRA2A", "TRA2B", "TRIM21", "TRIM25", "TRIP12", "TRMT11", "TROVE2", "TSC2", "TSG101", "TSPO", "TTC37", "TTK", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TXNDC12", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBR5", "UCK2", "UGCG", "UGDH", "UGP2", "UMPS", "UNC45A", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USP39", "VAMP7", "VAPA", "VARS1", "VARS2", "VCL", "VDAC1", "VDAC2", "VDAC3", "VPS25", "VPS37C", "VPS45", "VPS4A", "VPS4B", "VTA1", "VTI1B", "WARS", "WARS2", "WASL", "WBP11", "WDR61", "XAB2", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX3", "YKT6", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZFYVE16", "ZYX"], "leading_proteins": ["ACOX1", "ADAM17", "AIFM1", "AKT1", "ALDH1A2", "ANAPC2", "ASAH1", "ASNS", "ATP2A2", 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0.2414588001366878 0.0078467631279172 0.0802348466038066 0.0005470061355849 0.0075105395483816 0.0080495273899022 +Insertion of tail anchored proteins into the endoplasmic reticulum membrane 3 9 2.07421433449488 0.0380594095364053 4.016990291262136 10.99757281553398 1.1239772251284714 0.2752182956921286 1.9514004604865949 1.181365809872934 1.0815649178051203 0.2865915409883788 0.1407357406046216 1.0 0.1693528922958147 0.0768284795296569 0.0627230635966129 +Class a 1 rhodopsin like receptors 4 6 2.045469761917511 0.0408085673704483 2.8640776699029127 6.796116504854369 1.193322814833652 0.1851946070449122 1.2850789986620814 0.7987760455175396 1.3206182868906609 0.2426624676455473 1.0 1.0 0.1854358412925483 0.0914454637274335 0.0028896459807526 +Peptide ligand binding receptors 4 6 2.045469761917511 0.0408085673704483 2.8640776699029127 6.796116504854369 1.193322814833652 0.1851946070449122 1.2850789986620814 0.7987760455175396 1.3206182868906609 0.2426624676455473 1.0 1.0 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"signature_size": 3329, + "annotations_size": 1408, + "title": "Average number of proteins per term", + "value": 20.01278409090909 +} \ No newline at end of file diff --git a/msigdb_reactome/paths.json b/msigdb_reactome/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..5ee1cee153c32ee4d97a3102f6326ffcd5ee5046 --- /dev/null +++ b/msigdb_reactome/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_reactome/fragment/C342/C342_val_log2fc"} \ No newline at end of file diff --git a/msigdb_reactome/result.tsv b/msigdb_reactome/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..941bc1bcf7f90136c81182b7deab1222665f101c --- /dev/null +++ b/msigdb_reactome/result.tsv @@ -0,0 +1,423 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Protein localization 0.5459143229774356 3.0012430033712785 0.0026887989779251 0.977425351932279 0.3440493661230855 72 P21796,Q99595,P46379,P12235,O75874,Q9NR77,Q9NS69,Q15067,Q8N4Q1,Q5JRX3,O14925,P09601,Q8N4H5 13 +Cholesterol biosynthesis 0.8020754305498897 2.9263549379003817 0.0034295940639015 0.9920705210577214 0.3440493661230855 16 Q16850,Q15125,P37268,P48449,Q15392,Q15800,Q9BWD1,Q14739 8 +Metabolism of steroids 0.566204762701364 2.646386125562427 0.0081356891949626 0.999989889155912 0.3440493661230855 46 Q16850,Q15125,P37268,P48449,P38435,Q15392,Q15800,Q9BWD1,P30536,Q14739,P04062 11 +Mitochondrial protein import 0.6132276061914052 2.600802757378752 0.0093005911345309 0.999998067138973 0.3446113767742 35 P21796,Q99595,Q9NS69,O14925,Q8N4Q1,Q5JRX3,Q8N4H5 7 +Mtor signalling 0.7013252915338039 2.543783805181245 0.010965893332562 0.999999819088597 0.3758245123449769 18 P62942,P06730 2 +Sphingolipid metabolism 0.6433915480190671 2.5137014245627674 0.0119471532230108 0.9999999552817608 0.3758245123449769 25 Q16739,P17900,Q96G23,P51648,P07602,Q06136,P10619,O95470,Q13510,O15270,P04062 11 +Downstream signaling events of b cell receptor bcr 0.5348259448175513 2.3546213694361473 0.0185415875809429 0.9999999999964057 0.4109427237430454 45 P62942,P28070,P25786,P20618,P28074,P49721,P28072 7 +Signaling by the b cell receptor bcr 0.5195232791220582 2.27749234497718 0.0227568412389718 0.9999999999999916 0.4172382720133466 47 P62942,P28070,P25786,P20618,P28074,P49721,P28072 7 +Biological oxidations 0.5196050826533065 2.2696314834099884 0.0232299517436043 0.9999999999999958 0.4172382720133466 46 P07099,Q16850,O15217,Q9UJ14,Q9NUJ1,Q96DG6,O43169 7 +Mtorc1 mediated signalling 0.7448790814124125 2.252672976027863 0.0242797760732507 0.9999999999999992 0.4234947882577902 12 P62942 1 +Metabolism of cofactors 0.937683942002394 2.251356271029267 0.024362981426762 0.9999999999999992 0.4234947882577902 5 P00374,O75874,P35270 3 +Metabolism of folate and pterines 0.7678634006845961 2.1812169778261734 0.0291673716519598 1.0 0.4726379662363058 9 P00374,P41440,Q9H2D1,P34896 4 +Antigen processing cross presentation 0.4933568941804014 2.1285669178514897 0.0332901080013412 1.0 0.4873073013466599 54 P28070,P25786,P10321,P20618,Q9UIQ6,Q03518,P28074,P49721,P28072 9 +Slc mediated transmembrane transport 0.6264673601528256 2.1175580635653937 0.0342125129667945 1.0 0.4873073013466599 18 Q9UBX3,Q96QD8,P12235,Q70HW3,P35613 5 +Mrna decay by 3 to 5 exoribonuclease 0.6586188386161331 2.108867820826686 0.034955992497168 1.0 0.4873073013466599 15 Q969T7 1 +Gpcr ligand binding 0.7748359506159377 2.1006874666759465 0.0356684102492654 1.0 0.4894589549853089 8 P07602,P42892,Q9BYT8,Q9NRV9 4 +Cdt1 association with the cdc6 orc origin complex 0.5232491792625187 2.0914455453388605 0.0364881430262631 1.0 0.4894589549853089 40 P28070,P25786,Q9Y619,P20618,P28074,P49721,P28072 7 +Pink1 prkn mediated mitophagy 0.7385685793605429 2.080610106169075 0.0374696081145842 1.0 0.4930580207975195 10 P21796,Q9NS69,Q8N4H5 3 +Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.7444632500095646 2.07421433449488 0.0380594095364053 1.0 0.4961819317338765 9 P46379,P09601,P51648 3 +Class a 1 rhodopsin like receptors 0.8543575418777626 2.045469761917511 0.0408085673704483 1.0 0.505015357594387 6 P07602,P42892,Q9BYT8,Q9NRV9 4 +Peptide ligand binding receptors 0.8543575418777626 2.045469761917511 0.0408085673704483 1.0 0.505015357594387 6 P07602,P42892,Q9BYT8,Q9NRV9 4 +Mitotic g1 phase and g1 s transition 0.4426565161648207 2.0047751263884535 0.0449870928304518 1.0 0.5322842580275314 78 P28070,P25786,Q9Y619,P30154,P00374,P20618,P60900,Q9NR33,P31749,P28074,P30153,P49721,P28072 13 +Switching of origins to a post replicative state 0.4705746140011868 1.9772560010635911 0.0480127003814279 1.0 0.5444169323750921 58 P28070,P25786,Q9Y619,P60900,P20618,P28074,Q9UJX6,Q9UJX3,P49721,P28072 10 +Interleukin 4 and interleukin 13 signaling 0.6631175424249744 1.956780800217755 0.0503732453449654 1.0 0.5584687357930028 13 P31749,P04083,P09601 3 +Mitophagy 0.6595979655115446 1.9384634684032809 0.0525667036049737 1.0 0.5737513075643644 13 P21796,Q9NS69,Q8N4H5 3 +Transport of inorganic cations anions and amino acids oligopeptides 0.7080286606801428 1.9048574894695616 0.0567985984493533 1.0 0.5871687544884787 9 Q96QD8,Q70HW3 2 +Heme degradation 0.9437326242322768 1.896635629228859 0.0578760448045296 1.0 0.5871687544884787 4 P30519 1 +Glycosphingolipid metabolism 0.6201156100728795 1.8963975913510105 0.0579074901457277 1.0 0.5871687544884787 15 Q16739,P17900,P07602,P10619,Q13510,P04062 6 +Rhoa gtpase cycle 0.4728658399804336 1.8959104141629928 0.0579718916225333 1.0 0.5871687544884787 49 P30519,O15173,P41440,Q14739,Q8NBN3 5 +Ctla4 inhibitory signaling 0.8150833175535991 1.887883240122668 0.0590416270038307 1.0 0.5871687544884787 6 P30154,P30153 2 +Metabolism of porphyrins 0.6974771896105489 1.8867325467399156 0.0591963077402393 1.0 0.5871687544884787 10 P30519 1 +Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 0.4727759867115348 1.8802024021182056 0.0600804983659097 1.0 0.5871687544884787 47 P28070,P25786,P60900,P20618,P28074,Q9UJX6,Q9UJX3,P49721,P28072 9 +Glutathione conjugation 0.6064445388069369 1.875387309949407 0.0607394596564514 1.0 0.5871687544884787 16 O15217,Q9UJ14 2 +G1 s specific transcription 0.6946013787174601 1.8730009232733027 0.0610682574985208 1.0 0.5871687544884787 10 Q9Y619 1 +Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation 0.9372792998942372 1.8723043907631545 0.0611645036684751 1.0 0.5871687544884787 4 P00374,P35270 2 +Pyruvate metabolism 0.6143079351066718 1.8638932638193288 0.0623366948920705 1.0 0.5871687544884787 15 P21796,Q15120,O95563,P35613 4 +Sphingolipid de novo biosynthesis 0.6916158182121785 1.8587229744486435 0.0630664152374491 1.0 0.5871687544884787 10 O15270,Q06136,O95470,Q96G23 4 +Protein protein interactions at synapses 0.6168015050298954 1.8251900811964676 0.0679723500849645 1.0 0.5871687544884787 14 Q14168,P41440 2 +Glycerophospholipid biosynthesis 0.5301140944617009 1.8112815094882049 0.0700972864372935 1.0 0.5871687544884787 26 P48651,Q96N66,Q99829,Q9NPH0,Q8IV08,P43304,P67870,Q8NCC3,O15228,P35790,Q9NQZ5,O95674 12 +Potential therapeutics for sars 0.4897413309474111 1.7986418315283927 0.0720753557449138 1.0 0.5871687544884787 39 P62942,Q02790,P49356 3 +Regulation of pten stability and activity 0.478293676243967 1.788985550578411 0.0736171426377985 1.0 0.5871687544884787 42 P28070,P25786,P20618,P31749,P28074,P49721,P28072 7 +Orc1 removal from chromatin 0.4595509346553069 1.7860607248360345 0.0740894264625768 1.0 0.5871687544884787 50 P28070,P25786,Q9Y619,P20618,P28074,P49721,P28072 7 +Negative regulation of notch4 signaling 0.4811292981876773 1.7833022811048296 0.0745371102899412 1.0 0.5871687544884787 41 P28070,P25786,P20618,P31749,P28074,P49721,P28072 7 +Class i peroxisomal membrane protein import 0.675516868979407 1.7813444927629771 0.0748561901400455 1.0 0.5871687544884787 10 Q5T8D3,Q9NR77 2 +Degradation of dvl 0.4858140724315419 1.767211693721911 0.0771927820454754 1.0 0.5871687544884787 39 P28070,P25786,P60900,P20618,P28074,P49721,P28072 7 +Iron uptake and transport 0.5771131997514429 1.7627287215720064 0.0779462541779847 1.0 0.5871687544884787 17 P09601,P30519,Q9Y487 3 +Regulation of ras by gaps 0.4881625596389403 1.7608626745910902 0.0782616487517708 1.0 0.5871687544884787 38 P28070,P25786,P20618,P28074,P49721,P28072 6 +Signaling by notch4 0.4712016354378656 1.7600211072250294 0.0784042278539678 1.0 0.5871687544884787 43 P28070,P25786,P20618,P31749,P28074,P49721,P28072 7 +Degradation of axin 0.4909867099524987 1.7592955167529754 0.0785273276988944 1.0 0.5871687544884787 37 P28070,P25786,P20618,P28074,P49721,P28072 6 +Mitochondrial calcium ion transport 0.58601753376103 1.757589408832511 0.0788173967317631 1.0 0.5871687544884787 16 P21796,P45880,Q8WWC4 3 +Degradation of beta catenin by the destruction complex 0.454347661979919 1.7394122507602732 0.0819622748897663 1.0 0.5983720835928892 50 P28070,P25786,P30154,P20618,P28074,P30153,P49721,P28072 8 +Costimulation by the cd28 family 0.6012187442570811 1.7389660701422094 0.0820407312884354 1.0 0.5983720835928892 14 P30154,P31749,P30153 3 +Regulation of runx3 expression and activity 0.4882288095750117 1.7376353025225186 0.0822750952670097 1.0 0.5983720835928892 37 P28070,P25786,P20618,P28074,P49721,P28072 6 +Phase i functionalization of compounds 0.6002575663468402 1.733621529723453 0.0829852578432288 1.0 0.5983720835928892 14 P07099,Q96DG6,O43169 3 +Interferon gamma signaling 0.5963919120508636 1.7120967119550814 0.0868788472226249 1.0 0.600397220391458 14 P19474,P04439,P15260,P10321 4 +Regulation of hmox1 expression and activity 0.4540042371286362 1.7100470234071232 0.0872571779107158 1.0 0.600397220391458 46 P28070,P25786,P20618,P28074,P09601,P49721,P28072 7 +Cyclin a cdk2 associated events at s phase entry 0.4680771841222897 1.703929068400422 0.0883943396198669 1.0 0.6016201965067176 42 P28070,P25786,P20618,P31749,P28074,P49721,P28072 7 +G1 s dna damage checkpoints 0.4657802921656149 1.684701495976168 0.0920461777496546 1.0 0.6138477492383118 42 P28070,P25786,P60900,P20618,P28074,P49721,P28072 7 +Regulation of mrna stability by proteins that bind au rich elements 0.4276205009911401 1.6773464855364877 0.0934747474118871 1.0 0.6138477492383118 65 P28070,P25786,P60900,Q92945,P20618,Q01105,P28072,P31749,P28074,P49721,Q92973 11 +Fgfr1 mutant receptor activation 0.6528970247957122 1.6715413787262088 0.0946147926610134 1.0 0.6138477492383118 10 P62993,Q92614,O15164,O95429,O95684 5 +Collagen biosynthesis and modifying enzymes 0.6464460139703914 1.6702634994073928 0.0948672414695257 1.0 0.6138477492383118 11 P13674,Q32P28,O15460 3 +Stabilization of p53 0.4697000236942311 1.6624284752640983 0.0964268933991723 1.0 0.6138477492383118 40 P28070,P25786,P20618,P28074,P49721,P28072 6 +Formation of atp by chemiosmotic coupling 0.6499807659647172 1.6572954885863838 0.0974597489676381 1.0 0.6138477492383118 10 P00846 1 +Apc c mediated degradation of cell cycle proteins 0.4411901176800417 1.6550034697635525 0.097923794079046 1.0 0.6138477492383118 54 P28070,P25786,P60900,P20618,P28074,Q96DE5,Q9UJX6,Q9UJX3,P49721,P28072 10 +Signaling by fgfr1 in disease 0.6407466730727308 1.6419873926351878 0.1005926168719832 1.0 0.6138477492383118 11 P62993,Q92614,O15164,O95429,O95684 5 +Interconversion of nucleotide di and triphosphates 0.5244221006456301 1.63870321302182 0.1012750845812302 1.0 0.6138477492383118 22 P17812,Q9H773 2 +Apc cdc20 mediated degradation of nek2a 0.6460603073431066 1.6381126456779287 0.1013981975125597 1.0 0.6138477492383118 10 Q96DE5,O60566,Q9UJX6,Q9UJX3,Q16763 5 +Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components 0.6460603073431066 1.6381126456779287 0.1013981975125597 1.0 0.6138477492383118 10 Q96DE5,O60566,Q9UJX6,Q9UJX3,Q16763 5 +Initiation of nuclear envelope ne reformation 0.5558079444169375 1.6353465679926011 0.1019764166210477 1.0 0.6138477492383118 17 Q14739,Q86XL3 2 +Cross presentation of soluble exogenous antigens endosomes 0.4720035670384296 1.6318269940737429 0.1027159369992449 1.0 0.6138477492383118 38 P28070,P25786,P20618,P28074,P49721,P28072 6 +Hedgehog on state 0.4589529010872109 1.6273230651997674 0.1036685017037901 1.0 0.6138477492383118 42 P28070,P25786,P20618,P28074,P49721,P28072 6 +Synthesis of pg 0.9194469492034866 1.6228360532744146 0.1046244563786298 1.0 0.6138477492383118 2 O95674 1 +Pre notch processing in golgi 0.7781874751243236 1.6205629043113112 0.1051114133458217 1.0 0.6138477492383118 5 P16615,Q15363,P15291 3 +Ub specific processing proteases 0.4058924420434177 1.6205157705073263 0.1051215294155913 1.0 0.6138477492383118 73 P21796,P28070,P45880,P25786,P20618,Q96FW1,P28074,P49721,P28072 9 +Asymmetric localization of pcp proteins 0.4669405475153834 1.614693782182292 0.1063770247259574 1.0 0.6138477492383118 39 P28070,P25786,P60900,P20618,P28074,P49721,P28072 7 +Collagen formation 0.5762593112579283 1.5992266502997394 0.1097702507557301 1.0 0.6232117462260806 14 P13674,P07858,Q32P28,O15460 4 +Signaling by cytosolic fgfr1 fusion mutants 0.6618267239987132 1.5862086515404366 0.1126919858802901 1.0 0.6321526538623449 8 P62993,Q92614,O95684,O15164 4 +Metabolism of polyamines 0.4617997094848026 1.5727343924209969 0.1157803327175062 1.0 0.6432907914151158 39 P28070,P25786,P20618,P28074,P49721,P28072 6 +Hedgehog ligand biogenesis 0.4554364456530581 1.5704496276239093 0.1163105445489554 1.0 0.6432907914151158 41 P28070,P25786,P20618,P28074,P49721,P28072 6 +Cytoprotection by hmox1 0.4082757895053391 1.55547694808508 0.1198325204983699 1.0 0.6439854536706291 69 P28070,P25786,P60900,P20618,P30519,P28074,P09601,P49721,P28072,O75880 10 +Phase ii conjugation of compounds 0.4795411159370384 1.5526792552351991 0.120499780721974 1.0 0.6443616357546299 32 O15217,Q9UJ14,Q9NUJ1 3 +Degradation of gli1 by the proteasome 0.4526460276575921 1.5470539436097712 0.1218502384660142 1.0 0.6474156066420683 41 P28070,P25786,P20618,P28074,P49721,P28072 6 +Defective cftr causes cystic fibrosis 0.4484021996953661 1.537998444231924 0.1240489951788779 1.0 0.6517200940741071 42 P28070,P25786,P20618,P28074,P49721,P28072 6 +Abc transporter disorders 0.448402199695366 1.537998444231922 0.1240489951788783 1.0 0.6517200940741071 42 P28070,P25786,P20618,P28074,P49721,P28072 6 +Mastl facilitates mitotic progression 0.7571085470481644 1.534615561798824 0.1248782878285403 1.0 0.6536380269984567 5 P30154 1 +Platelet sensitization by ldl 0.7280941309537796 1.530093892146032 0.1259934898894186 1.0 0.6538988254811995 6 P30154 1 +Conversion from apc c cdc20 to apc c cdh1 in late anaphase 0.6483972812803394 1.523282884351952 0.1276879473355365 1.0 0.6561482841183777 8 Q16763,Q96DE5,Q9UJX6,Q9UJX3 4 +Transcriptional regulation by runx3 0.4464473848425531 1.5213626197172851 0.1281688639301856 1.0 0.6562245833225506 42 P28070,P25786,P20618,P28074,P49721,P28072 6 +Enos activation 0.8417162337108871 1.507356465762852 0.1317193112714272 1.0 0.663659384845578 4 P35270 1 +Ras processing 0.7224888931855009 1.5066779607165155 0.131893223397308 1.0 0.663659384845578 6 O60725,P49356 2 +Synaptic adhesion like molecules 0.7219713429718511 1.504514014602784 0.1324490675721643 1.0 0.663659384845578 6 P41440 1 +Regulation of lipid metabolism by pparalpha 0.5075237768278555 1.4998100365635527 0.1336636167638709 1.0 0.664558780940393 21 O60244,P37268,P23786,Q15067,Q13503 5 +Formyl peptide receptors bind formyl peptides and many other ligands 0.8887886985272013 1.49696867816241 0.1344014082607652 1.0 0.664558780940393 2 Q9NRV9 1 +Cristae formation 0.5106459387775721 1.4952518476614431 0.1348487268095617 1.0 0.664558780940393 20 Q5XKP0,O75964,Q9NX63,P00846,Q9Y512 5 +Metabolism of vitamins and cofactors 0.4433227220289227 1.494716284905395 0.1349885023785173 1.0 0.664558780940393 42 P78417,P43490,Q9H2D1,P00374,O75874,P34896,P31749,Q8N0U8,P35270,P41440,Q9BQG2 11 +Scf skp2 mediated degradation of p27 p21 0.4439642697920383 1.4739253887239403 0.14050168106797 1.0 0.6845203008432587 41 P28070,P25786,P20618,P28074,P49721,P28072 6 +Regulation of runx2 expression and activity 0.4369286376847252 1.4672069098254794 0.1423197778116047 1.0 0.6858003681734175 43 P28070,P25786,P20618,P28074,P49721,P28072 6 +Negative regulation of mapk pathway 0.588313261537033 1.4635856729543042 0.1433071894892805 1.0 0.6858003681734175 12 P30154,P30086,P30153 3 +Synthesis of dna 0.3982113807803324 1.458792399661137 0.144622255117585 1.0 0.6858003681734175 85 P28070,P25786,Q9Y619,Q9UJX3,P60900,P20618,Q9NR33,Q14181,P51530,P28074,Q9UJX6,P41440,P49721,P28072 14 +Immunoregulatory interactions between a lymphoid and a non lymphoid cell 0.7380809893937735 1.4566570520496884 0.1452110706229898 1.0 0.6858003681734175 5 Q5KU26,P04439,P10321 3 +Signaling by flt3 fusion proteins 0.73747235149987 1.454158240012011 0.1459024397981061 1.0 0.6858003681734175 5 P62993,Q92614 2 +Striated muscle contraction 0.6714567361980852 1.4533657253320271 0.1461222375369497 1.0 0.6858003681734175 7 P06753,P67936,P08670,P09493 4 +Cellular response to hypoxia 0.4404725141690257 1.4443717297121343 0.1486344385306008 1.0 0.6893965689417525 41 P28070,P25786,P20618,P28074,P49721,P28072 6 +Proton coupled monocarboxylate transport 0.8746618575292989 1.4389562920399648 0.1501629068079828 1.0 0.6922366011915911 2 P35613 1 +Transcriptional regulation by runx2 0.4191455732887725 1.4315099801759277 0.1522841087388426 1.0 0.6939029938650179 52 P28070,P25786,P60900,P20618,P31749,P28074,Q96PK6,P49721,P28072 9 +Auf1 hnrnp d0 binds and destabilizes mrna 0.4351726866524332 1.4249022943667746 0.1541854463449854 1.0 0.6969738523238163 42 P28070,P25786,P20618,P28074,P49721,P28072 6 +Dap12 interactions 0.729966333414034 1.4233183253706196 0.1546438970015078 1.0 0.6969738523238163 5 P62993,P10321 2 +Gamma carboxylation hypusine formation and arylsulfatase activation 0.6077352777752063 1.4223037891151182 0.1549380793873256 1.0 0.6969738523238163 9 O60725,P38435 2 +E2f mediated regulation of dna replication 0.5965468281993893 1.420158454008614 0.1555615558028495 1.0 0.6975499062751981 11 P30154,P30153,Q14181,Q9Y619 4 +Retrograde transport at the trans golgi network 0.4949915798318632 1.4169177711052972 0.1565069701189214 1.0 0.6987298264440901 21 Q5VZE5,Q7Z6M1,P53365,Q96JB2,O43752 5 +Metabolism of nitric oxide nos3 activation and regulation 0.663031728487838 1.4158575855682618 0.1568172053667134 1.0 0.6987298264440901 7 P35270 1 +Er to golgi anterograde transport 0.3866073046525649 1.4129074717908925 0.1576829318838668 1.0 0.7003708772633581 76 Q96JB2,O15027,Q9BVK6,P18085,Q96PC5,O43731,Q15363,Q92734,P24390,Q8IUR0,P84085,Q9Y6Y8,P49257 13 +Synthesis of leukotrienes lt and eoxins ex 0.8659452960625176 1.4031804334286253 0.1605630407740301 1.0 0.7050160445775834 2 Q14914 1 +Cell surface interactions at the vascular wall 0.5594570122625899 1.4018705732794732 0.1609538992251462 1.0 0.7050160445775834 13 P14174,P62993,P35613 3 +Endosomal vacuolar pathway 0.8108270676691745 1.38807806771638 0.1651132742863095 1.0 0.7197507436381542 4 P04439,Q9UIQ6,P10321 3 +Mapk family signaling cascades 0.3967843566683857 1.380901438514197 0.1673092676001883 1.0 0.7263367935053346 92 P28070,P25786,P30154,P60900,P20618,P49356,O43924,P30086,P28074,P30153,Q14168,P07196,O60725,P28482,P49721,P28072 16 +Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.5052493716918807 1.379775218631113 0.167655864978149 1.0 0.7263367935053346 18 Q02818,Q07065,Q9BTY2,P11047 4 +Ripk1 mediated regulated necrosis 0.5873515490837531 1.373494074098447 0.1695988021968113 1.0 0.7302602859116525 11 P49327,P41440 2 +Pp2a mediated dephosphorylation of key metabolic factors 0.8956593583182051 1.371413963626983 0.1702459469972357 1.0 0.730650343626168 3 P30154 1 +Egr2 and sox10 mediated initiation of schwann cell myelination 0.6150038505520744 1.3654575292783198 0.1721092929661591 1.0 0.730650343626168 8 Q16850,Q9NR77 2 +Collagen degradation 0.8545235948301795 1.356343567933741 0.1749898793997719 1.0 0.7332909231990443 2 P07858 1 +Tnfr2 non canonical nf kb pathway 0.4259105901953144 1.3450307326444788 0.1786153101236576 1.0 0.7440543096275442 42 P28070,P25786,P20618,P28074,P49721,P28072 6 +Dectin 1 mediated noncanonical nf kb signaling 0.4259105901953144 1.3450307326444788 0.1786153101236576 1.0 0.7440543096275442 42 P28070,P25786,P20618,P28074,P49721,P28072 6 +Tcf dependent signaling in response to wnt 0.3991144570803667 1.340914013055957 0.1799483719847041 1.0 0.745197963983716 62 P28070,P25786,P30154,P60900,P20618,P31749,P28074,P30153,P49721,P28072 10 +Intra golgi traffic 0.5211539174212563 1.327305013364862 0.1844078061289875 1.0 0.7521627031387428 15 Q96JB2,O43752,O95721,O00461 4 +Vitamin d calciferol metabolism 0.8811895194680883 1.3175828469344768 0.1876433307975387 1.0 0.7536787951412471 3 P04062 1 +Uch proteinases 0.4127660904621072 1.3107652919551478 0.1899370720361326 1.0 0.7543280076048999 45 P28070,P25786,P20618,P28074,Q8NB78,P49721,P28072 7 +Disassembly of the destruction complex and recruitment of axin to the membrane 0.5831030627510476 1.3006561692451015 0.1933761714800956 1.0 0.7543280076048999 9 P30154,P30153 2 +Transport of small molecules 0.4230450804167072 1.3003372155111423 0.1934854182081642 1.0 0.7543280076048999 145 P28070,P25786,Q9UBX3,P12235,P30519,Q9HD20,Q8WTV0,Q9NQ11,O15118,P28074,Q9Y487,Q8WWC4,Q70HW3,P53985,Q93050,P60900,P20618,P09601,P49721,P28072,P21796,P08183,P45880,Q9BUN8,Q96TA2,Q9BU23,P35613,P02786,Q96QD8,P16615 30 +Platelet aggregation plug formation 0.6710274741643452 1.2902093909207932 0.196977966449287 1.0 0.7543280076048999 6 P46108,P31749 2 +Integrin signaling 0.6710274741643452 1.2902093909207932 0.196977966449287 1.0 0.7543280076048999 6 P46108,P31749 2 +Smac xiap regulated apoptotic response 0.8379921851517733 1.2886846544793078 0.1975077395209705 1.0 0.7543280076048999 2 Q9NR28 1 +Keratan sulfate biosynthesis 0.8373910429816522 1.2862281368293011 0.198363454082123 1.0 0.7543280076048999 2 O43505 1 +Phospholipid metabolism 0.4098816054431516 1.284742194457259 0.1988823882836379 1.0 0.7543280076048999 45 P48651,Q96N66,Q99829,Q9NPH0,Q8IV08,Q9UBF8,P43304,P67870,Q8NCC3,O15228,P42356,P35790,Q9NQZ5,O95674 14 +Abc family proteins mediated transport 0.4046908682575409 1.2831832673365495 0.1994278767633965 1.0 0.7543280076048999 50 P08183,P28070,P25786,P60900,P20618,Q9BUN8,P28074,P49721,P28072 9 +Pcp ce pathway 0.404597398245032 1.2773099592510897 0.2014928389269741 1.0 0.7543280076048999 49 P28070,P25786,P60900,P20618,P28074,P49721,P28072 7 +Signaling by ctnnb1 phospho site mutants 0.5963838388008063 1.276747628728105 0.2016913603822931 1.0 0.7543280076048999 8 P30154 1 +Beta catenin phosphorylation cascade 0.5963838388008063 1.276747628728105 0.2016913603822931 1.0 0.7543280076048999 8 P30154 1 +Alpha oxidation of phytanate 0.7819095280086266 1.2762366328298644 0.2018718826500933 1.0 0.7543280076048999 4 Q9BY49 1 +Platelet homeostasis 0.5721787230802928 1.2705830387442083 0.2038770241554295 1.0 0.7551396987087367 10 P30154,P30153,Q16539,P16615,Q16537 5 +The role of gtse1 in g2 m progression after g2 checkpoint 0.4026716242305845 1.2642359617218784 0.2061453468106424 1.0 0.7551396987087367 50 P28070,P25786,P20618,P28074,P49721,P28072 6 +Runx1 regulates transcription of genes involved in differentiation of hscs 0.4164862244333699 1.2632093795139068 0.2065139429231015 1.0 0.7551396987087367 42 P28070,P25786,P20618,P28074,P49721,P28072 6 +Dna replication pre initiation 0.3876259685964412 1.2512172938851946 0.2108552103550893 1.0 0.7551396987087367 64 P28070,P25786,Q9Y619,P60900,P20618,Q9NR33,P28074,P49721,P28072 9 +Fceri mediated nf kb activation 0.4061540018146253 1.251033621256108 0.2109222112633939 1.0 0.7551396987087367 45 P28070,P25786,P20618,P28074,P49721,P28072 6 +Signaling by fgfr in disease 0.4696313853169913 1.2474912885939988 0.2122174124688367 1.0 0.7551396987087367 21 P62993,Q92614,P19388,O15164,O95429,O95684 6 +Signaling by notch 0.3893994880711754 1.241881797691012 0.2142801768986713 1.0 0.7580565052093698 62 P28070,P25786,P78536,P60900,O75832,P20618,Q99436,P31749,P28074,Q15363,P67809,P16615,P49721,P28072,P15291 15 +Ire1alpha activates chaperones 0.4474002878896818 1.2351753538198873 0.2167652497300136 1.0 0.7590155062241741 27 O43909,P43307,O43731,Q9NWM8 4 +Caspase activation via death receptors in the presence of ligand 0.8247670574090753 1.2347190566677388 0.2169350810312655 1.0 0.7590155062241741 2 P49327 1 +Regulation by c flip 0.8247670574090753 1.2347190566677388 0.2169350810312655 1.0 0.7590155062241741 2 P49327 1 +Copi dependent golgi to er retrograde traffic 0.3969394409140203 1.2278971497189808 0.2194855796318295 1.0 0.7590155062241741 53 Q9BVK6,P18085,Q9P2W9,Q02224,O43731,Q15363,P84085,P24390 8 +Antigen presentation folding assembly and peptide loading of class i mhc 0.5113816647355728 1.227720181999987 0.219552027581231 1.0 0.7590155062241741 14 Q9NZ08,P04439,Q03518,P10321 4 +Ion transport by p type atpases 0.5679106796563065 1.2251877185317686 0.2205045007590733 1.0 0.7590155062241741 9 Q9NQ11,Q9HD20 2 +Regulation of tp53 expression and degradation 0.5580042083257318 1.2235999334557333 0.2211031847329212 1.0 0.7590155062241741 11 P30154,P30153 2 +Cargo concentration in the er 0.5266922722767197 1.2207531229767954 0.2221795074270678 1.0 0.7590155062241741 13 Q96PC5,Q12907,P49755,Q15363,P49257 5 +S phase 0.3856374331970735 1.2202051329211028 0.2223871215425927 1.0 0.7590155062241741 96 P28070,P25786,Q9Y619,Q9UJX3,P60900,P20618,Q9NR33,Q14181,P31749,P51530,P28074,Q9UJX6,P41440,P49721,P28072 15 +Pyruvate metabolism and citric acid tca cycle 0.4315762537601511 1.2195451218040083 0.2226373608455851 1.0 0.7590155062241741 34 P21796,O95563,P48735,P35613 4 +Unblocking of nmda receptors glutamate binding and activation 0.6784083768273073 1.2106963443437435 0.2260118039797358 1.0 0.7622185531535711 5 Q14168 1 +Ras activation upon ca2 influx through nmda receptor 0.6784083768273073 1.2106963443437435 0.2260118039797358 1.0 0.7622185531535711 5 Q14168 1 +Long term potentiation 0.6784083768273073 1.2106963443437435 0.2260118039797358 1.0 0.7622185531535711 5 Q14168 1 +Fgfr2 alternative splicing 0.4865134515520085 1.210589202240707 0.2260528846090608 1.0 0.7622185531535711 17 P31943,P52597,Q01085,P09651 4 +Mapk6 mapk4 signaling 0.3967256006918476 1.2082835476703515 0.2269382146214884 1.0 0.7622185531535711 50 P28070,P25786,P20618,P28074,P49721,P28072 6 +Gene and protein expression by jak stat signaling after interleukin 12 stimulation 0.4484207856287172 1.202063130832196 0.2293390695839114 1.0 0.7623326804343953 25 P14174,P78417,P22626,P11233,O14979,Q13126 6 +Transport to the golgi and subsequent modification 0.3718661798761572 1.1986417080285818 0.2306672931514999 1.0 0.7623326804343953 81 Q8IUR0,Q9Y6Y8,O15027,Q9BVK6,P18085,Q96PC5,Q15363,O43731,Q92734,Q96JB2,O60476,P84085,P24390,P49257 14 +Resolution of d loop structures through synthesis dependent strand annealing sdsa 0.6139912908856291 1.1960714148858549 0.2316686914830712 1.0 0.7623326804343953 7 Q9UQ84 1 +Resolution of d loop structures 0.6139912908856291 1.1960714148858549 0.2316686914830712 1.0 0.7623326804343953 7 Q9UQ84 1 +Interleukin 12 signaling 0.4412791817857351 1.1901513079225026 0.2339869271832964 1.0 0.7635393010355018 27 P14174,P78417,P22626,P11233,O14979,Q13126 6 +Synthesis of very long chain fatty acyl coas 0.576784139331066 1.1829699054891023 0.236821074654141 1.0 0.7668754308293029 8 Q9P035,Q9NZ01 2 +Erks are inactivated 0.6454700698594521 1.1820423134852276 0.2371889117983334 1.0 0.7668754308293029 6 P30154,P30153 2 +Cellular response to chemical stress 0.368369157497834 1.177866091764897 0.2388499949912297 1.0 0.7668754308293029 79 P28070,P25786,P60900,P20618,P30519,P28074,P09601,P49721,P28072,O75880 10 +Phosphorylation of the apc c 0.5490407708549633 1.1775800998904111 0.2389640471871978 1.0 0.7668754308293029 11 Q9UJX4,Q96DE5,Q9UJX6,Q9UJX3,Q16763 5 +Regulation of glycolysis by fructose 2 6 bisphosphate metabolism 0.7524780562826037 1.162570487988538 0.2450038103781513 1.0 0.7704953571589979 4 P30154 1 +Apc c cdc20 mediated degradation of cyclin b 0.547771770295508 1.147220734105309 0.2512904043688784 1.0 0.7815184351890774 10 Q16763,Q96DE5,Q9UJX6,Q9UJX3 4 +Methylation 0.568562832485095 1.1435484410086638 0.2528109544803594 1.0 0.7815184351890774 8 P78417,P21964 2 +Tnf signaling 0.5457391559550735 1.136921120039171 0.2555712621962964 1.0 0.7815184351890774 10 O95429,O15111,P78536,Q8TCT8 4 +Inhibition of replication initiation of damaged dna by rb1 e2f1 0.6346658485479747 1.136273807186864 0.2558419893432626 1.0 0.7815184351890774 6 P30154,P30153,Q14181 3 +Interleukin 12 family signaling 0.4269611011607056 1.1195204695113974 0.2629181632661295 1.0 0.7815184351890774 30 P14174,P78417,P22626,P11233,O14979,Q13126 6 +Extracellular matrix organization 0.4225877151125421 1.1145425736486378 0.2650464908029013 1.0 0.7815184351890774 32 Q32P28,P11047,P78536,P13674,P07858,O75718,O15460,P35613 8 +Glycosaminoglycan metabolism 0.4783132416351052 1.1142595448907655 0.2651678569879376 1.0 0.7815184351890774 16 O43505,Q7LGA3,Q8NCH0,P54802,P15291,P08236 6 +Tcr signaling 0.3865698485745374 1.1122042567879349 0.2660503380861103 1.0 0.7815184351890774 50 P28070,P25786,P20618,P28074,P49721,P28072 6 +Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 0.7392036837174847 1.1114680107892625 0.2663669520203802 1.0 0.7815184351890774 4 P12235,P36404 2 +Deadenylation dependent mrna decay 0.4010693178106215 1.1057622938040237 0.2688294193630836 1.0 0.7815184351890774 41 Q969T7,Q6PGP7,P06730 3 +Negative regulation of nmda receptor mediated neuronal transmission 0.6265849632172984 1.1020480585802483 0.2704407788899212 1.0 0.7815184351890774 6 Q14168 1 +N glycan trimming and elongation in the cis golgi 0.7920048091373555 1.101982665783539 0.270469207664695 1.0 0.7815184351890774 2 O60476 1 +Nicotinate metabolism 0.7351926293723677 1.0960568497880785 0.2730538965212528 1.0 0.7815184351890774 4 P43490 1 +Intra golgi and retrograde golgi to er traffic 0.3791273585935242 1.0949726365544874 0.2735286246375972 1.0 0.7815184351890774 102 Q9P2W9,P18085,Q9BVK6,Q5VZE5,Q7Z6M1,P20645,O00461,Q02224,P53365,Q15363,O43731,O60476,Q13561,Q96JB2,O43752,O95721,P84085,P24390 18 +Response to elevated platelet cytosolic ca2 0.4170592046559103 1.0868772085389198 0.2770910800616746 1.0 0.786627982266201 33 Q9NTK5,O94919,P07602,Q9NUQ9,Q8NBX0 5 +Complement cascade 0.7880973850315587 1.0862706762983996 0.2773592564875002 1.0 0.786627982266201 2 P10909 1 +Interleukin 1 signaling 0.3841723535228503 1.0855767983768525 0.277666269308453 1.0 0.786627982266201 49 P28070,P25786,P20618,P28074,P49721,P28072 6 +Ros and rns production in phagocytes 0.556043970219003 1.0834663123619672 0.2786014957811784 1.0 0.7876925824495968 8 Q9Y487 1 +Glycogen storage diseases 0.7302255639097761 1.0769954161659387 0.2814823135260031 1.0 0.7909331829362596 4 P10253,Q04446,P46976 3 +Neddylation 0.3575717959146423 1.0736760707461117 0.2829678899174588 1.0 0.7909331829362596 77 P28070,Q5TAQ9,P25786,P20618,Q9BTE7,P28074,O94888,P49721,P28072 9 +Insulin receptor recycling 0.5369058947913582 1.070489897589615 0.2843988538662745 1.0 0.7909331829362596 9 Q9Y487 1 +Signaling by interleukins 0.3852180630555883 1.0694157892254224 0.28488235578268 1.0 0.7909331829362596 114 P14174,P28070,P25786,P30154,P28074,P30153,P60900,P20618,P09601,P49721,P28072,P78417,P22626,P11233,O14979,P31749,P52597,Q13126,P46108,P04083,P28482,P08670 22 +P38mapk events 0.7823865344153749 1.0633628412940652 0.2876174371496136 1.0 0.7909331829362596 2 P11233 1 +Negative regulation of the pi3k akt network 0.4764063856351728 1.0614999600610522 0.2884627510546085 1.0 0.7909331829362596 15 P30154,P31749,P30153,P28482 4 +Deubiquitination 0.3701648794024236 1.06031998243914 0.2889990514396177 1.0 0.7909331829362596 94 P21796,P28070,P45880,P25786,P20618,Q96FW1,P54725,P28074,Q8NB78,P49721,P28072 11 +Diseases of dna repair 0.5289528926442868 1.0517732751367448 0.2929035831474524 1.0 0.7909331829362596 10 Q9UQ84 1 +Dna replication 0.3661558956855192 1.0408551119268987 0.2979427974330702 1.0 0.7909331829362596 91 P28070,P25786,Q9Y619,Q9UJX3,P60900,P20618,Q9NR33,Q14181,P51530,P28074,Q9UJX6,P41440,P49721,P28072 14 +Cyclin a b1 b2 associated events during g2 m transition 0.52207624361547 1.038733972358598 0.2989284767576685 1.0 0.7909331829362596 11 P30154 1 +Mitochondrial biogenesis 0.4017662359276125 1.0352929102281947 0.3005321398230816 1.0 0.7909331829362596 37 Q5XKP0,Q04837,Q9BUR5,O75964,Q9NX63,P48735,P00846,Q9Y512,Q96RS0 9 +Transcriptional regulation by mecp2 0.4707745366934094 1.027857933245063 0.3040166600053722 1.0 0.7932797668065923 15 Q14739,Q13451 2 +Tp53 regulates transcription of cell death genes 0.6072918591826397 1.020433341900532 0.3075229877441476 1.0 0.7988789054312914 6 P49327 1 +Peroxisomal lipid metabolism 0.5171674004651381 1.013425340573748 0.3108570405328561 1.0 0.8031907163452606 11 Q9BY49,Q5T8D3,Q15067 3 +Interferon alpha beta signaling 0.5208906712223451 1.010850939043996 0.3120877784701972 1.0 0.8031907163452606 10 P01889,P04439,P10321 3 +Copii mediated vesicle transport 0.4141661324739594 0.999077171609802 0.3177573088364811 1.0 0.8090457338910767 28 O15027,Q15363,Q8IUR0,Q9Y6Y8,P49257 5 +Trna modification in the nucleus and cytosol 0.4589362392320075 0.9958114837725648 0.3193417495170187 1.0 0.8101498798557881 16 Q96PZ0,Q5VV42,O75648 3 +Apoptotic factor mediated response 0.5371342608939917 0.9927045858404476 0.320853939472485 1.0 0.8103247793518226 8 P28482,P42574,Q9NR28,P42771 4 +Aberrant regulation of mitotic exit in cancer due to rb1 defects 0.5198774417480962 0.9853792612600992 0.3244378126207299 1.0 0.8128264059964193 9 Q16763,Q96DE5,Q9UJX6,Q9UJX3 4 +Noncanonical activation of notch3 0.7616471295461205 0.980810533624582 0.3266861827773948 1.0 0.8155569953024324 2 P67809 1 +Selective autophagy 0.3969299129057335 0.9759216996255716 0.3291032678644821 1.0 0.8167894882538567 36 P21796,Q9NS69,O95140,P08670,Q8N4H5 5 +Copi mediated anterograde transport 0.3689856850825234 0.9756149377897434 0.3292553192321172 1.0 0.8167894882538567 56 Q9BVK6,P18085,Q15363,O43731,Q96JB2,P24390 6 +Beta catenin independent wnt signaling 0.3701161672484454 0.9737654062678278 0.3301730332632049 1.0 0.8167894882538567 54 P28070,P25786,P60900,P20618,P28074,P49721,P28072 7 +Signaling by ntrk2 trkb 0.6192270049797177 0.9671295615288952 0.3334792691774666 1.0 0.8167894882538567 5 P62993 1 +Rnd1 gtpase cycle 0.4472170523213147 0.964830440864226 0.3346297462262544 1.0 0.8167894882538567 17 P02786,Q9BXS4,P51648,P38159,O75976 5 +Signalling to ras 0.7826217678893479 0.9550813630953096 0.3395365529201966 1.0 0.8256778350805472 3 P62993,P11233 2 +Nicotinamide salvaging 0.7752609840986655 0.92859236903531 0.3531003780510047 1.0 0.8398063045537408 3 P43490 1 +Caspase activation via extrinsic apoptotic signalling pathway 0.6086735327799321 0.9240884918877548 0.3554402444774855 1.0 0.8414180833516418 5 P49327,P42574 2 +Diseases of glycosylation 0.4335463721212413 0.921667743022394 0.3567019110733496 1.0 0.8414180833516418 18 Q06210,O43505,Q8NCH0,P10619,O75340 5 +Clec7a dectin 1 signaling 0.3642476989891615 0.8991761059386426 0.3685588653556289 1.0 0.8491866697708841 50 P28070,P25786,P20618,P28074,P49721,P28072 6 +Signaling by fgfr2 0.4095993727806228 0.8989636003018752 0.3686720492478272 1.0 0.8491866697708841 24 P31943,P62993,P52597,P30153,P09651,P28482,Q01085 7 +Signaling by fgfr 0.4095993727806228 0.8989636003018752 0.3686720492478272 1.0 0.8491866697708841 24 P31943,P62993,P52597,P30153,P09651,P28482,Q01085 7 +Unfolded protein response upr 0.3686240549821016 0.883838553162695 0.3767833713021453 1.0 0.8491866697708841 44 Q06210,O43731,Q9NWM8,O43909,P43307 5 +Met promotes cell motility 0.4975082517660726 0.8737897140631352 0.3822327830354275 1.0 0.8491866697708841 9 P46108,P11047 2 +Hdr through homologous recombination hrr 0.3993941076531432 0.8721131680902968 0.3831466431367163 1.0 0.8491866697708841 26 Q9UQ84,Q9NR33,O14757,P41440,P51530 5 +Signaling by insulin receptor 0.4446913936699437 0.8720114842474207 0.3832021124923148 1.0 0.8491866697708841 15 P28482,Q93050,Q9Y487 3 +Fc epsilon receptor fceri signaling 0.3591511294564616 0.8714250227053407 0.3835221279760306 1.0 0.8491866697708841 55 P28070,P25786,P60900,P20618,P28074,P28482,P49721,P28072 8 +Hedgehog off state 0.3594836524822954 0.8692109303474584 0.3847317699862258 1.0 0.8491866697708841 54 P28070,P25786,P20618,P28074,P49721,P28072 6 +O linked glycosylation of mucins 0.6744324151263548 0.8655086264131893 0.3867596832675337 1.0 0.8491866697708841 4 O43505 1 +O linked glycosylation 0.6744324151263548 0.8655086264131893 0.3867596832675337 1.0 0.8491866697708841 4 O43505 1 +Rhog gtpase cycle 0.3775637340555155 0.8639586162974403 0.3876106246456625 1.0 0.8491866697708841 39 Q13576,P02786,Q86XL3,P34897,O15173,P49257,Q14739,P50402 8 +Regulation of mecp2 expression and activity 0.487291889351065 0.8596028449787307 0.390008006231247 1.0 0.8491866697708841 11 Q14739 1 +Myoclonic epilepsy of lafora 0.7297865945295994 0.8564752446686955 0.3917349600792741 1.0 0.8491866697708841 2 P46976 1 +Basigin interactions 0.5676249788706201 0.8537978072896589 0.3932170296406454 1.0 0.8491866697708841 6 P35613 1 +Antigen processing ubiquitination proteasome degradation 0.3499574254164792 0.8352724179509995 0.4035643435091307 1.0 0.8562244796939472 93 P19474,P28070,P25786,Q8IWV7,P20618,P60900,Q9UIQ6,P55786,P28074,Q9UJX6,Q9UJX3,P49721,P28072 13 +Rac3 gtpase cycle 0.3776501412277614 0.8334829377395582 0.404572416667929 1.0 0.8562244796939472 37 Q14739,Q9UQB8,O15173 3 +Cyclin d associated events in g1 0.4892444422875579 0.8327177902922741 0.4050039087188699 1.0 0.8562244796939472 9 P30154 1 +Interaction between l1 and ankyrins 0.6643336693726601 0.827960813012573 0.4076926929099915 1.0 0.858104949287002 4 Q13813,O15020 2 +Regulation of tnfr1 signaling 0.5319567732865794 0.8279095240193369 0.4077217408188951 1.0 0.858104949287002 7 O15111,Q8TCT8 2 +Signalling to erks 0.4871053201195928 0.8221058235228841 0.4110166713973864 1.0 0.8600899472827115 9 P46108,P28482,P11233 3 +Heme signaling 0.5011715795712579 0.8208719789224392 0.4117191935145934 1.0 0.8600899472827115 8 P09601,Q96RS0 2 +Transferrin endocytosis and recycling 0.4819690854862068 0.8138254820308959 0.4157449348858131 1.0 0.8650564478161402 10 Q93050,Q9Y487 2 +Recycling of eif2 gdp 0.52528597230585 0.7983459466069642 0.4246697616526833 1.0 0.8786687626000137 7 P05198,Q9UI10,Q13144,P20042,Q9NR50,P49770 6 +Ion channel transport 0.3913560070705141 0.7900719686974754 0.4294857392587676 1.0 0.880226959063093 25 Q93050,Q9HD20,Q9Y487 3 +Activation of gene expression by srebf srebp 0.406175219006273 0.7880025885931925 0.4306951917400139 1.0 0.8802902813692574 19 P48449,Q16850,Q9UBM7,P37268 4 +Interleukin 1 family signaling 0.3511140097269564 0.7866949015654419 0.4314604893761857 1.0 0.8802902813692574 54 P28070,P25786,P20618,P28074,P49721,P28072 6 +Synthesis of pc 0.5743445495693594 0.7857440334789776 0.4320174605299409 1.0 0.8802902813692574 5 P35790,Q9NQZ5 2 +Ptk6 regulates proteins involved in rna processing 0.7294046903186846 0.7668834501432941 0.4431508143534173 1.0 0.8913662094423023 3 O75525,Q07666 2 +The citric acid tca cycle and respiratory electron transport 0.3500293985841034 0.765814510378426 0.443786679056809 1.0 0.8913718175634624 101 P21796,P35613,O43676,P20674,O75964,Q9UDW1,O75306,Q9NPL8,O75438,O95168,P48735,Q86Y39,P00846,Q16134,Q15120,O75880,O95563,O14949 18 +Metabolism of water soluble vitamins and cofactors 0.3748666603863634 0.7639783129250759 0.4448801665903934 1.0 0.8922952629049486 34 P78417,P43490,Q9H2D1,P00374,P34896,P41440,Q9BQG2 7 +G2 m checkpoints 0.3371827261924928 0.7510657800608036 0.4526130688089396 1.0 0.898842314362464 86 Q9UQ84,P28070,P25786,Q9Y619,P60900,P20618,P51530,P28074,P49721,P28072 10 +Activated notch1 transmits signal to the nucleus 0.7236921226698645 0.7472261478007161 0.4549270630420503 1.0 0.9021652179763476 3 Q92542,P78536 2 +Cytochrome c mediated apoptotic response 0.6417991285526942 0.7453355809226236 0.4560688764835878 1.0 0.9031574937959096 4 P28482,Q9NR28 2 +Regulation of cholesterol biosynthesis by srebp srebf 0.3836937867277377 0.7347560763122316 0.4624880618889948 1.0 0.9087476062438782 25 P48449,Q16850,Q9UBM7,P37268 4 +Disorders of transmembrane transporters 0.325718641927923 0.7347354908424286 0.4625006011981407 1.0 0.9087476062438782 74 P28070,P25786,P20618,P28074,Q9BTX1,P49721,P28072,P35613 8 +Rnd2 gtpase cycle 0.4019357979972039 0.7190965700368633 0.4720814205377597 1.0 0.9087476062438782 18 Q07065,P02786,P51648,P38159,Q9Y2I1 5 +Organelle biogenesis and maintenance 0.3496202642341423 0.7187721171146692 0.4722813402401107 1.0 0.9087476062438782 106 Q04837,Q96CS2,Q86X55,P30153,Q99996,P48735,A6NIH7,P00846,Q9H6D7,Q92973,P78371,O95684,Q68CZ6,P18085,Q9BUR5,A0AVF1,P00367,O95613,Q9NX63,Q13561,Q9Y512,Q96RS0,Q5XKP0,O75964,O43924,O00471,O43805,P48643 28 +Cd28 co stimulation 0.4764477452978664 0.7042570063795283 0.4812727356421571 1.0 0.9087476062438782 8 P31749,P62993 2 +Translocation of slc2a4 glut4 to the plasma membrane 0.3573243809221501 0.6903283360628064 0.4899877322350288 1.0 0.9087476062438782 39 O60343,P31749,Q9UIQ6 3 +Transcriptional regulation by ventx 0.4185466798005144 0.6874074452710167 0.491826007195896 1.0 0.9087476062438782 14 Q9UJX4,Q96DE5,Q9HCE1,Q9UJX6,Q9UJX3,Q16763 6 +Signaling by wnt in cancer 0.4560375642223674 0.6841095533153403 0.4939059897592188 1.0 0.9087476062438782 10 P30154 1 +Rhod gtpase cycle 0.3715851134082813 0.6791822721911094 0.4970223784808545 1.0 0.9087476062438782 28 Q14739,O15173 2 +Signaling by pdgf 0.4968078249335536 0.6736240428414059 0.5005503636294768 1.0 0.9087476062438782 7 P46108 1 +Downstream signal transduction 0.4968078249335536 0.6736240428414059 0.5005503636294768 1.0 0.9087476062438782 7 P46108 1 +Assembly and cell surface presentation of nmda receptors 0.4479773623764218 0.6595022125958645 0.5095733257301469 1.0 0.9087476062438782 11 Q14168 1 +C type lectin receptors clrs 0.3381047300115526 0.6583570272322055 0.5103087417018215 1.0 0.9087476062438782 54 P28070,P25786,P20618,P28074,P49721,P28072 6 +Transport of bile salts and organic acids metal ions and amine compounds 0.6159295787051282 0.6529279497281317 0.5138027292277818 1.0 0.9087476062438782 4 P35613 1 +Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux 0.5397333305847878 0.6501378807202864 0.5156031622797626 1.0 0.9087476062438782 5 Q8NB78,Q9HCE1 2 +Fatty acyl coa biosynthesis 0.401838840710532 0.6482736120300931 0.5168079981687885 1.0 0.9087476062438782 16 P50897,P49327,Q9UMR5,Q9NZ01 4 +Pten regulation 0.3321552608108856 0.6468451884603057 0.5177321429287369 1.0 0.9087476062438782 62 P28070,P25786,P60900,O75832,P20618,Q99436,P31749,Q9Y2Q5,P28074,Q9HCE1,P28482,P49721,P28072 13 +Degradation of the extracellular matrix 0.433940369654378 0.6420789597945533 0.5208219163677734 1.0 0.9087476062438782 12 P17655,P78536,P11047,P07858,P42574,P35613 6 +Constitutive signaling by akt1 e17k in cancer 0.4880120632013021 0.6357268751687072 0.5249544563675925 1.0 0.9087476062438782 7 P31749 1 +Activation of rac1 downstream of nmdars 0.6693718064322232 0.6330721260031636 0.5266865437882553 1.0 0.9087476062438782 2 Q14012 1 +Nef and signal transduction 0.6693718064322162 0.6330721260031381 0.526686543788272 1.0 0.9087476062438782 2 Q13177 1 +Transport of vitamins nucleosides and related molecules 0.5136099465096391 0.6328928552918882 0.5268036138116936 1.0 0.9087476062438782 6 P12235,P36404 2 +Map2k and mapk activation 0.4453240716407732 0.6312022937871627 0.5279082623645555 1.0 0.9087476062438782 10 P28482,P30086 2 +Diseases associated with glycosaminoglycan metabolism 0.5334779698655268 0.6261984098314268 0.531184810112677 1.0 0.9087476062438782 5 Q8NCH0 1 +Class i mhc mediated antigen processing presentation 0.3492185440058656 0.625532681509251 0.531621505744676 1.0 0.9087476062438782 117 P19474,P28070,P25786,P10321,Q9UJX3,Q8IWV7,P20618,Q9UIQ6,Q03518,P55786,P28074,Q9UJX6,Q9NZ08,P49721,P28072 15 +Activation of smo 0.6645626690712318 0.6162151255549349 0.537752546891479 1.0 0.9111378893179332 2 P48729 1 +Diseases associated with n glycosylation of proteins 0.528009642798636 0.6054406691812673 0.5448862355005213 1.0 0.9155129111989664 5 O75340,Q13724,P15291 3 +Rnd3 gtpase cycle 0.3776960345624982 0.6021829876898817 0.5470523386026727 1.0 0.915623999284426 19 Q07065,Q9Y2I1,P38159 3 +Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 0.320699122971204 0.5991706782030227 0.5490590738225727 1.0 0.915623999284426 69 Q8N183,O43676,P20674,O75964,Q9Y6M9,Q9NPL8,Q9UDW1,O75306,O75438,O95168,Q16134,Q86Y39,P00846,O75880,O14949 15 +Signaling by hedgehog 0.328190195045433 0.5902287183504983 0.5550373210337609 1.0 0.915623999284426 60 P28070,P25786,P20618,P28074,P49721,P28072 6 +Dna damage reversal 0.5234657039711075 0.5883196092216509 0.5563177859614452 1.0 0.915623999284426 5 Q9C0B1,Q9H1I8,Q8N3C0,Q6P6C2 4 +Cargo trafficking to the periciliary membrane 0.3675572128050557 0.5850925484895655 0.5584854889671353 1.0 0.915623999284426 23 P18085,O43924,O00471,A6NIH7,P48643 5 +Erk mapk targets 0.4378010821346668 0.5813793875212268 0.5609847864811548 1.0 0.915623999284426 9 P30154,P30153 2 +Mapk targets nuclear events mediated by map kinases 0.4378010821346668 0.5813793875212268 0.5609847864811548 1.0 0.915623999284426 9 P30154,P30153 2 +Akt phosphorylates targets in the cytosol 0.4995916062739166 0.5775038058701563 0.563599168386987 1.0 0.915623999284426 6 P31749 1 +Synthesis of substrates in n glycan biosythesis 0.3844352263053896 0.5746198696710332 0.5655484109973083 1.0 0.915623999284426 17 P10619,Q86YN1,Q9Y5P6 3 +Platelet calcium homeostasis 0.6707757065544068 0.5721631655865278 0.5672114392862828 1.0 0.915623999284426 3 P16615,P30626 2 +Reduction of cytosolic ca levels 0.6707757065544068 0.5721631655865278 0.5672114392862828 1.0 0.915623999284426 3 P16615,P30626 2 +Acyl chain remodelling of pg 0.6513375413285267 0.5707213365060497 0.5681885532064044 1.0 0.915623999284426 2 Q92604 1 +Carnitine metabolism 0.4972700375582454 0.5684337293853032 0.5697404928985319 1.0 0.915623999284426 6 O43772 1 +Cilium assembly 0.3176796548242335 0.5656750509022797 0.5716146984169108 1.0 0.915623999284426 69 P18085,O95613,P48643,Q96CS2,A0AVF1,O43924,Q13561,P30153,Q99996,O00471,A6NIH7,O43805,Q9H6D7,Q92973,P78371,O95684,Q68CZ6 17 +Met activates rap1 and rac1 0.4947671313598972 0.5586903931973374 0.5763730368460245 1.0 0.9160047606455112 6 P46108 1 +G alpha i signalling events 0.3557621134146377 0.5530211482388935 0.5802489289147919 1.0 0.9166563058144124 26 P30154,P07602,P04083,P30153,Q9NRV9 5 +Formation of apoptosome 0.6610270613591128 0.5415699080200966 0.588114826569162 1.0 0.9184067141881676 3 Q9NR28 1 +Fcgamma receptor fcgr dependent phagocytosis 0.351575816098489 0.5357405933799355 0.5921378444546386 1.0 0.9232891306668118 29 P46108,P28482,Q8IV08,Q9UQB8 4 +Rhoc gtpase cycle 0.3473449257373482 0.5331537954534895 0.5939271227209564 1.0 0.924778616327576 33 Q14739,P41440 2 +Nr1h2 and nr1h3 mediated signaling 0.4575242646536214 0.5075478234008696 0.611770489860713 1.0 0.9335541738469246 7 P49327,Q8NB78,Q9HCE1 3 +Intrinsic pathway for apoptosis 0.3596843380437467 0.5061655912847388 0.6127404079988028 1.0 0.9335541738469246 21 Q9NR28,P31749,P42771,P28482,P42574 5 +Parasite infection 0.3596698133665332 0.4958158188310927 0.6200243630823472 1.0 0.9346834081583992 20 P46108,P28482,Q9UQB8 3 +Sulfur amino acid metabolism 0.41543844458654 0.486868649354042 0.6263514172047615 1.0 0.9409067652350472 10 Q13126 1 +Diseases associated with glycosylation precursor biosynthesis 0.4278580376592774 0.4828255036123269 0.6292196406241937 1.0 0.9434944132043288 8 P10619 1 +Rho gtpases activate ktn1 0.4165703830608948 0.4814322924327374 0.6302092902933674 1.0 0.9439730646096396 9 P84095,Q07866,Q9NSK0,Q9H0B6 4 +Separation of sister chromatids 0.3308917676402702 0.4748822355453859 0.6348709139824544 1.0 0.9442322847098334 109 P28070,P25786,P30154,O75832,P28074,P30153,Q9UJX6,Q96EA4,P60900,P20618,O43683,Q02224,Q96DE5,Q9H900,Q8NBT2,P49721,P28072,Q99436,O60566,Q16763,Q9UJX4,Q9UJX3,Q53HL2 23 +Signaling by moderate kinase activity braf mutants 0.400842641419338 0.4723231568645931 0.6366961439380514 1.0 0.9442322847098334 12 P30086 1 +Rac2 gtpase cycle 0.3341933809723206 0.4709417331900071 0.6376823446528057 1.0 0.9442322847098334 37 Q14739,Q86XL3,O15173 3 +Estrogen dependent nuclear events downstream of esr membrane signaling 0.4905064478442604 0.4681579073385298 0.6396716710070189 1.0 0.9442322847098334 5 P31749 1 +Raf activation 0.4089126033389316 0.4672901692778632 0.6402922889292855 1.0 0.9442322847098334 11 P30154 1 +Signaling by wnt 0.3090459238172138 0.4333101715415844 0.6647894496294047 1.0 0.9662706925586684 85 P28070,P25786,P30154,P60900,P20618,P31749,P28074,P30153,P49721,P28072 10 +Signaling by vegf 0.3361953869159604 0.4155596118169472 0.6777322858121353 1.0 0.9725905791696704 27 P31749,Q9UQB8 2 +Apoptosis 0.3145429942850241 0.4139905698881422 0.6788810130400011 1.0 0.9725905791696704 94 P28070,P25786,Q9NR28,P60900,P20618,P28482,P31749,P28074,P49327,P49721,P28072,O60313 12 +Activation of the pre replicative complex 0.3437747845528801 0.4127786352890625 0.6797688058429938 1.0 0.9725905791696704 22 Q9NR33,Q14181,Q9Y619 3 +Creb1 phosphorylation through nmda receptor mediated activation of ras signaling 0.4010776336254248 0.4106891370706989 0.6813004933142277 1.0 0.972891576659668 9 P07196,Q14168 2 +Metabolism of lipids 0.3639188248309944 0.4065311368136211 0.6843523836367551 1.0 0.9756518604596052 181 P50897,Q16739,P37268,Q16836,Q9NPH0,Q9P035,Q15392,Q8IV08,P51648,Q15067,P07602,Q06136,Q14739,Q9BY49,P35790,O60244,P17900,Q96G23,Q9H4L5,O43772,Q15800,Q14914,Q9UMR5,Q9BWD1,Q13510,P04062,P09960,Q16850,P48449,P23786,Q9UBF8,P30536,Q8NCC3,Q13503,Q9NZ01,P42126,P10619,P49327,O95470,P42356,O15270,Q9NQZ5,P06280,Q15165,Q15125,P38435,Q9UBM7,Q5T8D3,Q01469,O95674 50 +Synthesis of bile acids and bile salts 0.4535058681913983 0.4043096795370686 0.6859850084479282 1.0 0.9756518604596052 6 O14734,Q96SU4,Q9H4L5,P22059,P51659 5 +Bile acid and bile salt metabolism 0.4535058681913983 0.4043096795370686 0.6859850084479282 1.0 0.9756518604596052 6 O14734,Q96SU4,Q9H4L5,P22059,P51659 5 +Cd163 mediating an anti inflammatory response 0.6143467521704198 0.4042821985203777 0.6860052143856599 1.0 0.9756518604596052 3 P78536 1 +Rora activates gene expression 0.4683841183809731 0.3922877062748032 0.6948456461450723 1.0 0.977426713213788 5 Q96RS0 1 +Signaling by ptk6 0.3656784988191867 0.392207592156248 0.6949048349038369 1.0 0.977426713213788 14 O75525,P46108,P31749 3 +Nuclear events kinase and transcription factor activation 0.3841673076908871 0.3900235268616345 0.6965191499437167 1.0 0.977426713213788 12 P30154,P28482,P30153 3 +Signaling by retinoic acid 0.3822834203725256 0.3809014067184316 0.7032764086268941 1.0 0.977426713213788 12 Q01469,Q15120,O94788 3 +Metalloprotease dubs 0.4254512045541471 0.3799204021238764 0.7040045021662398 1.0 0.977426713213788 7 O95630,Q92783 2 +Plasma lipoprotein assembly remodeling and clearance 0.3417971824905482 0.3757926851698998 0.7070710262917208 1.0 0.977426713213788 19 Q8WTV0 1 +Heparan sulfate heparin hs gag metabolism 0.4618354494226914 0.3707023220910043 0.7108592605986106 1.0 0.977426713213788 5 Q7LGA3,P54802 2 +Disinhibition of snare formation 0.5837090471896598 0.3621508485228054 0.7172393072121745 1.0 0.977426713213788 2 Q12846 1 +Pre notch expression and processing 0.3852337663940305 0.3565086772595411 0.721459654921093 1.0 0.977426713213788 11 P16615,Q15363,Q9HCE1,P15291 4 +Ksrp khsrp binds and destabilizes mrna 0.3546689623710909 0.352143295436607 0.7247308001939488 1.0 0.977426713213788 15 P31749,Q92945,Q16539 3 +Intracellular signaling by second messengers 0.3040873896802363 0.348129882455194 0.7277426433631178 1.0 0.977426713213788 88 P28070,P25786,P30154,P60900,P20618,P31749,P28074,P30153,P28482,P49721,P28072 11 +Darpp 32 events 0.3849013040035177 0.346628707656377 0.7288702759489663 1.0 0.977426713213788 10 P30154 1 +Mitotic spindle checkpoint 0.3046180788057569 0.34530129723085 0.7298678715312825 1.0 0.977426713213788 59 Q96EA4,P30154,Q9UJX4,O43683,Q02224,Q9H900,P30153,Q9UJX6,Q96DE5,Q8NBT2,O60566,Q16763,Q53HL2,Q9UJX3 14 +Signaling by braf and raf1 fusions 0.3331690602196215 0.3443597986018984 0.7305757181664845 1.0 0.977426713213788 22 Q9NRY5,P30086,P51114 3 +Golgi to er retrograde transport 0.295443788043944 0.3438733600675525 0.7309415270715209 1.0 0.977426713213788 78 Q9P2W9,P18085,Q9BVK6,Q02224,Q15363,O43731,Q13561,P84085,P24390 9 +Rho gtpases activate wasps and waves 0.345287851974469 0.3430901042148942 0.7315306755141464 1.0 0.977426713213788 17 P28482,Q7L576,P62993,Q9UQB8 4 +Ncam signaling for neurite out growth 0.4355546386861098 0.3416463917614057 0.7326170200797839 1.0 0.977426713213788 6 P28482,P62993,O15020 3 +Homologous dna pairing and strand exchange 0.3481787523313985 0.3369802850514835 0.7361317620585797 1.0 0.977426713213788 16 Q9UQ84,P51530 2 +Keratan sulfate keratin metabolism 0.4338285544865295 0.3357925053019337 0.7370273422604867 1.0 0.977426713213788 6 O43505 1 +Ra biosynthesis pathway 0.4455475330926611 0.3189506819975155 0.7497639110797805 1.0 0.979704206710698 5 O94788,Q9BTZ2,Q9HBH5,Q8TC12 4 +Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein 0.3302264648362704 0.3113253342191773 0.7555533096648257 1.0 0.9831969131313074 20 P10619,Q86YN1,Q9Y5P6,Q06210 4 +Lagging strand synthesis 0.3294452561999673 0.3065945321876553 0.7591520160178766 1.0 0.98507009369066 20 Q9Y2S7,P51530,Q14181,P41440 4 +Cdc42 gtpase cycle 0.3131157378289324 0.2910500858329751 0.7710130137937825 1.0 0.9932171303034272 36 Q14739 1 +Mitotic g2 g2 m phases 0.3043649645681628 0.2791743882505388 0.7801109977602405 1.0 1.0 96 P28070,P25786,P30154,P20618,P28074,P30153,Q9H6D7,P49721,P28072,O95684 10 +Hdr through single strand annealing ssa 0.3396264008609039 0.2725356135227952 0.7852102115932567 1.0 1.0 15 Q9UQ84 1 +Aurka activation by tpx2 0.3095011441857159 0.2713567956666722 0.7861166278300962 1.0 1.0 37 O95613,Q96CS2,Q13561,P30153,Q99996,O43805,Q9H6D7,O95684,Q68CZ6 9 +Platelet activation signaling and aggregation 0.2975646391109867 0.2692939369785653 0.7877034975000781 1.0 1.0 57 Q9NTK5,P62993,O94919,P46108,P07602,P31749,P28482,Q9NUQ9,Q8N2K0,Q8NBX0 10 +Met receptor recycling 0.4125200078421772 0.2662821927473836 0.790021886301806 1.0 1.0 6 P46108 1 +Peroxisomal protein import 0.3225579004964829 0.2653409664227585 0.7907468085032958 1.0 1.0 20 O75874,Q15067 2 +Signaling by ntrks 0.3125320593909548 0.2616645766730557 0.7935800529210155 1.0 1.0 32 P62993,P30154,P46108,P11233,P30153,P28482 6 +Polymerase switching 0.3371047920440377 0.2448591003904241 0.8065655309399458 1.0 1.0 14 Q9Y2S7,Q14181,P41440 3 +Vegfr2 mediated cell proliferation 0.547203848466613 0.2403511143031926 0.8100580726028346 1.0 1.0 3 O43865,P19174 2 +Miscellaneous transport and binding events 0.4184717208182967 0.2397424790847037 0.8105299015426899 1.0 1.0 5 Q9UEY8,Q8N4V1,P35611,Q9UNS2 4 +Dna replication initiation 0.3672996758412057 0.2346600413691091 0.8144726041316759 1.0 1.0 8 Q9NR33,Q14181 2 +Vitamin b5 pantothenate metabolism 0.4739906376879724 0.2287312157660976 0.8190778312078022 1.0 1.0 4 P49327 1 +Insulin receptor signalling cascade 0.3992243107639587 0.2257236720060557 0.8214163456017374 1.0 1.0 6 P28482 1 +Signal attenuation 0.5387353848740674 0.2229880942398668 0.8235447726517111 1.0 1.0 3 P28482 1 +Diseases of carbohydrate metabolism 0.3552738443301556 0.2209169986542768 0.8251570613909212 1.0 1.0 10 P15586,P46976,P10253,Q04446,P54802,P08236 6 +Response of eif2ak1 hri to heme deficiency 0.5333734215273591 0.2124070015081766 0.8317895239874593 1.0 1.0 3 P08243,P05198 2 +Activation of ppargc1a pgc 1alpha by phosphorylation 0.5315694527961335 0.2089196995646982 0.8345109254593384 1.0 1.0 3 P54646,Q16539 2 +Regulation of tp53 activity 0.2914967483036604 0.2087096397802391 0.8346749144082 1.0 1.0 51 Q9UQ84,Q92804,P30154,P30153,P51530 5 +Gpvi mediated activation cascade 0.4049338146811089 0.2036914380072387 0.8385946334121408 1.0 1.0 5 Q06124,P61586,P84095,P63000 4 +Syndecan interactions 0.4541353383458684 0.1857248886283496 0.852660509579628 1.0 1.0 4 O14936,P12814,Q9Y296 3 +Runx2 regulates bone development 0.4531207048775046 0.1836600707316832 0.8542801349289308 1.0 1.0 4 Q96PK6 1 +Chylomicron assembly 0.5022542831379735 0.1805822719002687 0.8566954720731437 1.0 1.0 2 P07237 1 +Notch3 intracellular domain regulates transcription 0.4971445746919153 0.1721010766805014 0.8633580663249203 1.0 1.0 2 P42224 1 +Prolonged erk activation events 0.3785727641786597 0.1675228096824281 0.8669587015920333 1.0 1.0 6 P46108 1 +Processing of smdt1 0.3390373379568541 0.1605230871050257 0.8724690365566643 1.0 1.0 11 P35232,Q10713,Q8IYU8,Q96TA2,Q8WWC4 5 +Abc transporters in lipid homeostasis 0.4881274421400646 0.1579823217619857 0.8744707289613289 1.0 1.0 2 P40855 1 +Synthesis of pips at the golgi membrane 0.3373962597267289 0.1515658068073674 0.8795294039842254 1.0 1.0 10 P42356 1 +Mucopolysaccharidoses 0.4338207875191344 0.1469023321489893 0.8832091111068072 1.0 1.0 4 P54802,P08236 2 +Smooth muscle contraction 0.3228240643925887 0.1437114798363976 0.8857283057070413 1.0 1.0 13 P06753,P67936,P04083,P09493 4 +Notch4 activation and transmission of signal to the nucleus 0.4709948902915556 0.1340922911494326 0.8933295953634512 1.0 1.0 2 Q92542 1 +Processive synthesis on the lagging strand 0.3135181938033506 0.133774330059151 0.8935810263627073 1.0 1.0 14 Q9Y2S7,P51530,Q14181 3 +Regulation of ifng signaling 0.4243609022556431 0.1306496167678514 0.8960524905833418 1.0 1.0 4 P15260,P42224,P18031 3 +Transport and synthesis of paps 0.4667868951006942 0.1288000462940635 0.8975158688982452 1.0 1.0 2 O43252 1 +Metabolism of steroid hormones 0.3621545626200903 0.125776228622161 0.8999090591288972 1.0 1.0 6 P30536 1 +Mismatch repair 0.3240714726782577 0.1236552962027071 0.9015882083760224 1.0 1.0 12 Q9UQ84 1 +Chl1 interactions 0.4538623384430533 0.1139158018566799 0.9093045390404472 1.0 1.0 2 P11142 1 +Molecules associated with elastic fibres 0.45386233844304 0.1139158018566656 0.9093045390404584 1.0 1.0 2 P55081 1 +Elastic fibre formation 0.45386233844304 0.1139158018566656 0.9093045390404584 1.0 1.0 2 P55081 1 +Biosynthesis of specialized proresolving mediators spms 0.4694777012163387 0.1115038844554504 0.9112167854603396 1.0 1.0 3 Q14914 1 +Diseases of signal transduction by growth factor receptors and second messengers 0.3258405656809349 0.1082311232864196 0.9138123571458514 1.0 1.0 152 P62942,P28070,P62993,P25786,Q92614,P19388,P30154,O75832,P28074,P30153,Q9NRY5,O95684,P67936,P60900,P20618,O15164,P30086,Q92734,P49721,P28072,O15111,P51114,Q99436,P31749,Q9UBW7,Q6UN15,P78536,O95429,Q07866,P28482 30 +Polymerase switching on the c strand of the telomere 0.2978277332646647 0.107378486181547 0.9144887213554213 1.0 1.0 18 P0CG13,Q9Y2S7,Q14181,P41440 4 +Growth hormone receptor signaling 0.3532675002008986 0.1049522831909657 0.9164136720233688 1.0 1.0 6 P28482 1 +Leishmania infection 0.2866587301136245 0.1016553957193471 0.9190302077226428 1.0 1.0 38 O14641,Q9UQB8,P46108,P09601,P28482 5 +Telomere c strand lagging strand synthesis 0.2900025094549634 0.1006034718465021 0.9198652405572794 1.0 1.0 25 Q9Y2S7,P0CG13,Q14181,P41440,P51530 5 +Transcriptional regulation by runx1 0.2776149003132866 0.099123704895316 0.9210400509877944 1.0 1.0 64 P28070,P25786,P20618,P28074,P49721,P28072 6 +Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol 0.4530968129885744 0.0930095813536543 0.9258959494014802 1.0 1.0 3 O14734,P51659 2 +Beta oxidation of pristanoyl coa 0.4530968129885744 0.0930095813536543 0.9258959494014802 1.0 1.0 3 O14734,P51659 2 +Phase 0 rapid depolarisation 0.4271115118725761 0.0892811252956608 0.9288584939911716 1.0 1.0 2 Q9HD47 1 +Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde 0.4271115118725544 0.089281125295644 0.928858493991185 1.0 1.0 2 P52292 1 +Camk iv mediated phosphorylation of creb 0.4271115118725544 0.089281125295644 0.928858493991185 1.0 1.0 2 P52292 1 +Anchoring of the basal body to the plasma membrane 0.2854264946252868 0.087665191341746 0.9301427863571332 1.0 1.0 37 O95613,Q96CS2,Q13561,P30153,Q99996,O43805,Q9H6D7,O95684,Q68CZ6 9 +Pd 1 signaling 0.4241058010219601 0.0869953340114751 0.930675220966764 1.0 1.0 2 P41240 1 +Sars cov infections 0.2725869799049086 0.0785240718645174 0.9374111827600052 1.0 1.0 69 P62942,Q02790,P49356 3 +Hs gag degradation 0.437285335657777 0.0778205004146177 0.9379708389275084 1.0 1.0 3 P54802 1 +Maturation of sars cov 1 spike protein 0.3434951943770792 0.0739096047446194 0.9410823132732156 1.0 1.0 5 P26572 1 +Regulation of tp53 activity through phosphorylation 0.2851085693882128 0.070522991408397 0.943777401608493 1.0 1.0 32 Q9UQ84,Q92804,P40938,O14757,Q00535,P51530 6 +Fceri mediated mapk activation 0.3171377523817493 0.0693672889835971 0.9446972657885376 1.0 1.0 8 P28482,P62993 2 +Regulation of ifna signaling 0.4242333132892252 0.0671343506572075 0.9464747477007524 1.0 1.0 3 P42224,P18031 2 +Rac1 gtpase cycle 0.2733187509441193 0.0642075084391478 0.9488049988637336 1.0 1.0 46 Q14739,Q9UQB8 2 +Wnt mediated activation of dvl 0.4193076404345587 0.0635125752709654 0.9493583458436592 1.0 1.0 3 O14641 1 +Recruitment of mitotic centrosome proteins and complexes 0.2814746020515563 0.0633204938603725 0.9495112967678568 1.0 1.0 38 O95613,Q96CS2,Q13561,P30153,Q99996,O43805,Q9H6D7,O95684,Q68CZ6 9 +Diseases of mitotic cell cycle 0.3017788658539094 0.0591453582473142 0.9528363311950055 1.0 1.0 13 Q16763,Q96DE5,Q9UJX6,Q9UJX3 4 +Inactivation of cdc42 and rac1 0.4046903187011407 0.0540062515672715 0.9569301834823016 1.0 1.0 3 P63000,O94813 2 +Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1 0.3962717979555081 0.0493215356600153 0.960663057426736 1.0 1.0 3 P06493,P20248 2 +Runx3 regulates p14 arf 0.3017733694018568 0.048191858394273 0.9615633387104288 1.0 1.0 2 P42771 1 +Fructose metabolism 0.3935658448586932 0.0479305916240426 0.9617715588112664 1.0 1.0 3 Q3LXA3,Q00796 2 +Uptake and function of diphtheria toxin 0.3545864661654179 0.045678467392715 0.963566526422928 1.0 1.0 4 P08238,P07900,Q16881 3 +Caspase mediated cleavage of cytoskeletal proteins 0.3225474303634377 0.0429947818582939 0.9657056934828404 1.0 1.0 6 P08670 1 +Activation of the ap 1 family of transcription factors 0.361329264957037 0.0351463194130999 0.9719630666580276 1.0 1.0 3 P28482 1 +Asparagine n linked glycosylation 0.3006619096061679 0.0349873778278073 0.9720898057464016 1.0 1.0 121 Q86YN1,O43731,Q9Y6Y8,P24390,P18085,Q92734,Q8IUR0,Q9Y5P6,Q9BVK6,Q96PC5,Q06210,Q9BUN8,Q13561,P49257,P10619,P84085,O15027,Q15363,Q96JB2,O60476 20 +Nef mediated downregulation of mhc class i complex cell surface expression 0.3382541605525661 0.0338428228086765 0.9730024878253668 1.0 1.0 4 Q9BXS5,P04439 2 +N glycan antennae elongation in the medial trans golgi 0.3419823595850818 0.0302590956931429 0.9758604185307064 1.0 1.0 3 P15291 1 +Adaptive immune system 0.3371054598262407 0.0268902205092564 0.9785472936015434 1.0 1.0 193 P62942,P28070,P25786,P30154,Q9UIQ6,P28074,P30153,Q9UJX6,P10321,Q8IWV7,P20618,P60900,P49721,P28072,P19474,P31749,P07858,Q9NZ08,P10619,Q03518,P55786,Q9UJX3 22 +Adp signalling through p2y purinoceptor 1 0.3054720384846719 0.0249537110423882 0.9800918853356524 1.0 1.0 3 Q16539,P63218 2 +Rho gtpases activate iqgaps 0.2995780590717364 0.0234357522790788 0.9813026866362664 1.0 1.0 11 Q13576,P63000,Q9BVA1,P46940,Q13509,Q9BUF5,P35222,P04350,P35221,P60953 10 +Wax and plasmalogen biosynthesis 0.3175375956939642 0.0224062846903597 0.9821238671534926 1.0 1.0 4 O15228 1 +Cd28 dependent vav1 pathway 0.3100831753141617 0.0223572055519595 0.982163016833178 1.0 1.0 6 P62993 1 +Termination of translesion dna synthesis 0.2764519376354654 0.0184265230629903 0.9852985936880948 1.0 1.0 19 Q9NR33,P41440 2 +Oncogene induced senescence 0.3038549997815821 0.0166841000592878 0.9866886317116286 1.0 1.0 7 P28482,Q9HCE1,P42771 3 +Muscle contraction 0.2754170357333872 0.0123998808206789 0.9901065800685356 1.0 1.0 29 P06753,P67936,Q13177,P09493,P04083,Q99996,P16615,P08670 8 +Dna strand elongation 0.2738650491856016 0.0032626989187591 0.9973967475248672 1.0 1.0 29 Q9Y2S7,P51530,Q14181,P41440 4 diff --git a/msigdb_reactome/selections.json b/msigdb_reactome/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..06ee0a23eb5b435a48e6561ae6b80b649711070b --- /dev/null +++ b/msigdb_reactome/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2 ltr circle formation", "A tetrasaccharide linker sequence is required for gag synthesis", "Abacavir metabolism", "Abacavir transmembrane transport", "Abacavir transport and metabolism", "Abc family proteins mediated transport", "Abc transporter disorders", "Abc transporters in lipid homeostasis", "Aberrant regulation of mitotic exit in cancer due to rb1 defects", "Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects", "Abortive elongation of hiv 1 transcript in the absence of tat", "Acetylcholine neurotransmitter release cycle", "Acetylcholine regulates insulin secretion", "Activated notch1 transmits signal to the nucleus", "Activated ntrk2 signals through cdk5", "Activated ntrk2 signals through frs2 and frs3", "Activated ntrk2 signals through fyn", "Activated ntrk2 signals through pi3k", "Activated ntrk2 signals through ras", "Activated ntrk3 signals through ras", "Activated pkn1 stimulates transcription of ar androgen receptor regulated genes klk2 and klk3", "Activated tak1 mediates p38 mapk activation", "Activation of ampk downstream of nmdars", "Activation of anterior hox genes in hindbrain development during early embryogenesis", "Activation of atr in response to replication stress", "Activation of bad and translocation to mitochondria", "Activation of bh3 only proteins", "Activation of caspases through apoptosome mediated cleavage", "Activation of gene expression by srebf srebp", "Activation of irf3 irf7 mediated by tbk1 ikk epsilon", "Activation of kainate receptors upon glutamate binding", "Activation of nima kinases nek9 nek6 nek7", "Activation of nmda receptors and postsynaptic events", "Activation of noxa and translocation to mitochondria", "Activation of ppargc1a pgc 1alpha by phosphorylation", "Activation of puma and translocation to mitochondria", "Activation of rac1", "Activation of rac1 downstream of nmdars", "Activation of smo", "Activation of the ap 1 family of transcription factors", "Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s", "Activation of the pre replicative complex", "Activation of the tfap2 ap 2 family of transcription factors", "Acyl chain remodeling of cl", "Acyl chain remodelling of pc", "Acyl chain remodelling of pe", "Acyl chain remodelling of pg", "Acyl chain remodelling of pi", "Acyl chain remodelling of ps", "Adaptive immune system", "Adenylate cyclase inhibitory pathway", "Adherens junctions interactions", "Adora2b mediated anti inflammatory cytokines production", "Adp signalling through p2y purinoceptor 1", "Adp signalling through p2y purinoceptor 12", "Adrenaline noradrenaline inhibits insulin secretion", "Advanced glycosylation endproduct receptor signaling", "Aflatoxin activation and detoxification", "Aggrephagy", "Akt phosphorylates targets in the cytosol", "Akt phosphorylates targets in the nucleus", "Alk mutants bind tkis", "Alpha linolenic omega3 and linoleic omega6 acid metabolism", "Alpha oxidation of phytanate", "Alpha protein kinase 1 signaling pathway", "Amino acid transport across the plasma membrane", "Amino acids regulate mtorc1", "Ampk inhibits chrebp transcriptional activation activity", "Amyloid fiber formation", "Anchoring of the basal body to the plasma membrane", "Androgen biosynthesis", "Anti inflammatory response favouring leishmania parasite infection", "Antigen activates b cell receptor bcr leading to generation of second messengers", "Antigen presentation folding assembly and peptide loading of class i mhc", "Antigen processing cross presentation", "Antigen processing ubiquitination proteasome degradation", "Antimicrobial peptides", "Antiviral mechanism by ifn stimulated genes", "Apc c cdc20 mediated degradation of cyclin b", "Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1", "Apc c mediated degradation of cell cycle proteins", "Apc cdc20 mediated degradation of nek2a", "Apex1 independent resolution of ap sites via the single nucleotide replacement pathway", "Apobec3g mediated resistance to hiv 1 infection", "Apoptosis", "Apoptosis induced dna fragmentation", "Apoptotic cleavage of cell adhesion proteins", "Apoptotic cleavage of cellular proteins", "Apoptotic execution phase", "Apoptotic factor mediated response", "Aquaporin mediated transport", "Arachidonate production from dag", "Arachidonic acid metabolism", "Arms mediated activation", "Aryl hydrocarbon receptor signalling", "Asparagine n linked glycosylation", "Aspartate and asparagine metabolism", "Assembly and cell surface presentation of nmda receptors", "Assembly of active lpl and lipc lipase complexes", "Assembly of collagen fibrils and other multimeric structures", "Assembly of the hiv virion", "Assembly of the orc complex at the origin of replication", "Association of tric cct with target proteins during biosynthesis", "Asymmetric localization of pcp proteins", "Atf4 activates genes in response to endoplasmic reticulum stress", "Atf6 atf6 alpha activates chaperone genes", "Atf6 atf6 alpha activates chaperones", "Attachment and entry", "Attachment of gpi anchor to upar", "Attenuation phase", "Auf1 hnrnp d0 binds and destabilizes mrna", "Aurka activation by tpx2", "Autophagy", "B wich complex positively regulates rrna expression", "Base excision repair", "Base excision repair ap site formation", "Basigin interactions", "Bbsome mediated cargo targeting to cilium", "Beta catenin independent wnt signaling", "Beta catenin phosphorylation cascade", "Beta oxidation of butanoyl coa to acetyl coa", "Beta oxidation of decanoyl coa to octanoyl coa coa", "Beta oxidation of hexanoyl coa to butanoyl coa", "Beta oxidation of lauroyl coa to decanoyl coa coa", "Beta oxidation of octanoyl coa to hexanoyl coa", "Beta oxidation of pristanoyl coa", "Beta oxidation of very long chain fatty acids", "Bh3 only proteins associate with and inactivate anti apoptotic bcl 2 members", "Bile acid and bile salt metabolism", "Binding and uptake of ligands by scavenger receptors", "Binding of tcf lef ctnnb1 to target gene promoters", "Biological oxidations", "Biosynthesis of epa derived spms", "Biosynthesis of maresins", "Biosynthesis of specialized proresolving mediators spms", "Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein", "Biotin transport and metabolism", "Bmal1 clock npas2 activates circadian gene expression", "Branched chain amino acid catabolism", "Budding and maturation of hiv virion", "Butyrate response factor 1 brf1 binds and destabilizes mrna", "C type lectin receptors clrs", "Ca dependent events", "Ca2 pathway", "Calcineurin activates nfat", "Calnexin calreticulin cycle", "Camk iv mediated phosphorylation of creb", "Carboxyterminal post translational modifications of tubulin", "Cardiac conduction", "Cargo concentration in the er", "Cargo recognition for clathrin mediated endocytosis", "Cargo trafficking to the periciliary membrane", "Carnitine metabolism", "Caspase activation via death receptors in the presence of ligand", "Caspase activation via dependence receptors in the absence of ligand", "Caspase activation via extrinsic apoptotic signalling pathway", "Caspase mediated cleavage of cytoskeletal proteins", "Cation coupled chloride cotransporters", "Cd163 mediating an anti inflammatory response", "Cd209 dc sign signaling", "Cd28 co stimulation", "Cd28 dependent pi3k akt signaling", "Cd28 dependent vav1 pathway", "Cdc42 gtpase cycle", "Cdc6 association with the orc origin complex", "Cdt1 association with the cdc6 orc origin complex", "Cell cell communication", "Cell cell junction organization", "Cell cycle", "Cell cycle checkpoints", "Cell cycle mitotic", "Cell death signalling via nrage nrif and nade", "Cell extracellular matrix interactions", "Cell junction organization", "Cell surface interactions at the vascular wall", "Cellular response to chemical stress", "Cellular response to heat stress", "Cellular response to hypoxia", "Cellular response to starvation", "Cellular responses to stimuli", "Cellular senescence", "Chaperone mediated autophagy", "Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex", "Chl1 interactions", "Cholesterol biosynthesis", "Choline catabolism", "Chondroitin sulfate dermatan sulfate metabolism", "Chrebp activates metabolic gene expression", "Chromatin modifying enzymes", "Chromosome maintenance", "Chylomicron assembly", "Chylomicron clearance", "Cilium assembly", "Circadian clock", "Citric acid cycle tca cycle", "Class a 1 rhodopsin like receptors", "Class b 2 secretin family receptors", "Class i mhc mediated antigen processing presentation", "Class i peroxisomal membrane protein import", "Clathrin mediated endocytosis", "Clec7a dectin 1 induces nfat activation", "Clec7a dectin 1 signaling", "Clec7a inflammasome pathway", "Cobalamin cbl vitamin b12 transport and metabolism", "Coenzyme a biosynthesis", "Cohesin loading onto chromatin", "Collagen biosynthesis and modifying enzymes", "Collagen degradation", "Collagen formation", "Competing endogenous rnas cernas regulate pten translation", "Complement cascade", "Complex i biogenesis", "Condensation of prometaphase chromosomes", "Condensation of prophase chromosomes", "Constitutive signaling by aberrant pi3k in cancer", "Constitutive signaling by akt1 e17k in cancer", "Constitutive signaling by egfrviii", "Constitutive signaling by ligand responsive egfr cancer variants", "Constitutive signaling by overexpressed erbb2", "Conversion from apc c cdc20 to apc c cdh1 in late anaphase", "Cooperation of pdcl phlp1 and tric cct in g protein beta folding", "Cooperation of prefoldin and tric cct in actin and tubulin folding", "Copi dependent golgi to er retrograde traffic", "Copi independent golgi to er retrograde traffic", "Copi mediated anterograde transport", "Copii mediated vesicle transport", "Costimulation by the cd28 family", "Creatine metabolism", "Creb phosphorylation", "Creb1 phosphorylation through nmda receptor mediated activation of ras signaling", "Creb1 phosphorylation through the activation of adenylate cyclase", "Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde", "Cristae formation", "Crmps in sema3a signaling", "Cross presentation of soluble exogenous antigens endosomes", "Cs ds degradation", "Ctla4 inhibitory signaling", "Cyclin a b1 b2 associated events during g2 m transition", "Cyclin a cdk2 associated events at s phase entry", "Cyclin d associated events in g1", "Cytochrome c mediated apoptotic response", "Cytochrome p450 arranged by substrate type", "Cytokine signaling in immune system", "Cytoprotection by hmox1", "Cytosolic iron sulfur cluster assembly", "Cytosolic sensors of pathogen associated dna", "Cytosolic sulfonation of small molecules", "Cytosolic trna aminoacylation", "Dag and ip3 signaling", "Dap12 interactions", "Dap12 signaling", "Darpp 32 events", "Dcc mediated attractive signaling", "Ddx58 ifih1 mediated induction of interferon alpha beta", "Deactivation of the beta catenin transactivating complex", "Deadenylation dependent mrna decay", "Deadenylation of mrna", "Death receptor signalling", "Dectin 1 mediated noncanonical nf kb signaling", "Defective b4galt1 causes b4galt1 cdg cdg 2d", "Defective cftr causes cystic fibrosis", "Defective chst14 causes eds musculocontractural type", "Defective factor ix causes hemophilia b", "Defective intrinsic pathway for apoptosis", "Defective ripk1 mediated regulated necrosis", "Defects in biotin btn metabolism", "Defects in cobalamin b12 metabolism", "Defects in vitamin and cofactor metabolism", "Defects of contact activation system cas and kallikrein kinin system kks", "Degradation of axin", "Degradation of beta catenin by the destruction complex", "Degradation of cysteine and homocysteine", "Degradation of dvl", "Degradation of gli1 by the proteasome", "Degradation of the extracellular matrix", "Depolymerisation of the nuclear lamina", "Deposition of new cenpa containing nucleosomes at the centromere", "Dermatan sulfate biosynthesis", "Detoxification of reactive oxygen species", "Deubiquitination", "Developmental biology", "Dex h box helicases activate type i ifn and inflammatory cytokines production", "Digestion", "Digestion and absorption", "Disassembly of the destruction complex and recruitment of axin to the membrane", "Diseases associated with glycosaminoglycan metabolism", "Diseases associated with glycosylation precursor biosynthesis", "Diseases associated with n glycosylation of proteins", "Diseases associated with o glycosylation of proteins", "Diseases of carbohydrate metabolism", "Diseases of dna repair", "Diseases of glycosylation", "Diseases of immune system", "Diseases of metabolism", "Diseases of mismatch repair mmr", "Diseases of mitotic cell cycle", "Diseases of programmed cell death", "Diseases of signal transduction by growth factor receptors and second messengers", "Disinhibition of snare formation", "Disorders of transmembrane transporters", "Displacement of dna glycosylase by apex1", "Dissolution of fibrin clot", "Dna damage bypass", "Dna damage recognition in gg ner", "Dna damage reversal", "Dna damage telomere stress induced senescence", "Dna double strand break repair", "Dna double strand break response", "Dna methylation", "Dna repair", "Dna replication", "Dna replication initiation", "Dna replication pre initiation", "Dna strand elongation", "Dopamine clearance from the synaptic cleft", "Dopamine neurotransmitter release cycle", "Downregulation of erbb2 erbb3 signaling", "Downregulation of erbb2 signaling", "Downregulation of erbb4 signaling", "Downregulation of smad2 3 smad4 transcriptional activity", "Downregulation of tgf beta receptor signaling", "Downstream signal transduction", "Downstream signaling events of b cell receptor bcr", "Downstream signaling of activated fgfr1", "Downstream signaling of activated fgfr2", "Downstream signaling of activated fgfr3", "Downstream signaling of activated fgfr4", "Dscam interactions", "Dual incision in gg ner", "Dual incision in tc ner", "E2f enabled inhibition of pre replication complex formation", "E2f mediated regulation of dna replication", "E3 ubiquitin ligases ubiquitinate target proteins", "Early phase of hiv life cycle", "Ecm proteoglycans", "Effects of pip2 hydrolysis", "Egfr downregulation", "Egfr interacts with phospholipase c gamma", "Egfr transactivation by gastrin", "Egr2 and sox10 mediated initiation of schwann cell myelination", "Elastic fibre formation", "Endogenous sterols", "Endosomal sorting complex required for transport escrt", "Endosomal vacuolar pathway", "Energy dependent regulation of mtor by lkb1 ampk", "Enos activation", "Eph ephrin mediated repulsion of cells", "Eph ephrin signaling", "Epha mediated growth cone collapse", "Ephb mediated forward signaling", "Ephrin signaling", "Epigenetic regulation of gene expression", "Er quality control compartment erqc", "Er to golgi anterograde transport", "Erbb2 activates ptk6 signaling", "Erbb2 regulates cell motility", "Ercc6 csb and ehmt2 g9a positively regulate rrna expression", "Erk mapk targets", "Erks are inactivated", "Erythropoietin activates phospholipase c gamma plcg", "Erythropoietin activates ras", "Esr mediated signaling", "Establishment of sister chromatid cohesion", "Estrogen biosynthesis", "Estrogen dependent gene expression", "Estrogen dependent nuclear events downstream of esr membrane signaling", "Estrogen stimulated signaling through prkcz", "Ethanol oxidation", "Eukaryotic translation elongation", "Eukaryotic translation initiation", "Export of viral ribonucleoproteins from nucleus", "Extension of telomeres", "Extra nuclear estrogen signaling", "Extracellular matrix organization", "Factors involved in megakaryocyte development and platelet production", "Fanconi anemia pathway", "Fasl cd95l signaling", "Fatty acid metabolism", "Fatty acids bound to gpr40 ffar1 regulate insulin secretion", "Fatty acyl coa biosynthesis", "Fbxw7 mutants and notch1 in cancer", "Fc epsilon receptor fceri signaling", "Fceri mediated ca 2 mobilization", "Fceri mediated mapk activation", "Fceri mediated nf kb activation", "Fcgamma receptor fcgr dependent phagocytosis", "Fcgr3a mediated il10 synthesis", "Fertilization", "Fgfr1 mutant receptor activation", "Fgfr2 alternative splicing", "Fgfr2 mutant receptor activation", "Fibronectin matrix formation", "Flt3 signaling", "Flt3 signaling by cbl mutants", "Flt3 signaling in disease", "Folding of actin by cct tric", "Formation of apoptosome", "Formation of atp by chemiosmotic coupling", "Formation of fibrin clot clotting cascade", "Formation of incision complex in gg ner", "Formation of rna pol ii elongation complex", "Formation of senescence associated heterochromatin foci sahf", "Formation of tc ner pre incision complex", "Formation of the beta catenin tcf transactivating complex", "Formation of the cornified envelope", "Formation of the early elongation complex", "Formation of tubulin folding intermediates by cct tric", "Formation of xylulose 5 phosphate", "Formyl peptide receptors bind formyl peptides and many other ligands", "Foxo mediated transcription", "Foxo mediated transcription of oxidative stress metabolic and neuronal genes", "Free fatty acids regulate insulin secretion", "Frs mediated fgfr1 signaling", "Frs mediated fgfr2 signaling", "Frs mediated fgfr3 signaling", "Frs mediated fgfr4 signaling", "Fructose catabolism", "Fructose metabolism", "G alpha 12 13 signalling events", "G alpha i signalling events", "G alpha q signalling events", "G alpha s signalling events", "G alpha z signalling events", "G beta gamma signalling through cdc42", "G beta gamma signalling through pi3kgamma", "G protein activation", "G protein beta gamma signalling", "G protein mediated events", "G0 and early g1", "G1 s dna damage checkpoints", "G1 s specific transcription", "G2 m checkpoints", "G2 m dna damage checkpoint", "G2 m dna replication checkpoint", "G2 phase", "Gab1 signalosome", "Gaba b receptor activation", "Gaba receptor activation", "Gaba synthesis release reuptake and degradation", "Galactose catabolism", "Gamma carboxylation hypusine formation and arylsulfatase activation", "Gamma carboxylation transport and amino terminal cleavage of proteins", "Gap filling dna repair synthesis and ligation in gg ner", "Gap junction assembly", "Gap junction degradation", "Gap junction trafficking and regulation", "Gastrin creb signalling pathway via pkc and mapk", "Gdp fucose biosynthesis", "Gene and protein expression by jak stat signaling after interleukin 12 stimulation", "Gene silencing by rna", "Generation of second messenger molecules", "Global genome nucleotide excision repair gg ner", "Glucagon like peptide 1 glp1 regulates insulin secretion", "Glucagon signaling in metabolic regulation", "Glucagon type ligand receptors", "Gluconeogenesis", "Glucose metabolism", "Glucuronidation", "Glutamate and glutamine metabolism", "Glutamate neurotransmitter release cycle", "Glutathione conjugation", "Glutathione synthesis and recycling", "Glycerophospholipid biosynthesis", "Glycerophospholipid catabolism", "Glycogen breakdown glycogenolysis", "Glycogen metabolism", "Glycogen storage diseases", "Glycogen synthesis", "Glycolysis", "Glycosaminoglycan metabolism", "Glycosphingolipid metabolism", "Glyoxylate metabolism and glycine degradation", "Golgi associated vesicle biogenesis", "Golgi cisternae pericentriolar stack reorganization", "Golgi to er retrograde transport", "Gp1b ix v activation signalling", "Gpcr ligand binding", "Gpvi mediated activation cascade", "Grb2 events in erbb2 signaling", "Grb2 sos provides linkage to mapk signaling for integrins", "Growth hormone receptor signaling", "Hats acetylate histones", "Hcmv early events", "Hcmv infection", "Hcmv late events", "Hdacs deacetylate histones", "Hdl assembly", "Hdl clearance", "Hdms demethylate histones", "Hdr through homologous recombination hrr", "Hdr through mmej alt nhej", "Hdr through single strand annealing ssa", "Hedgehog ligand biogenesis", "Hedgehog off state", "Hedgehog on state", "Heme biosynthesis", "Heme degradation", "Heme signaling", "Hemostasis", "Heparan sulfate heparin hs gag metabolism", "Hiv elongation arrest and recovery", "Hiv infection", "Hiv life cycle", "Hiv transcription elongation", "Hiv transcription initiation", "Homologous dna pairing and strand exchange", "Homology directed repair", "Host interactions of hiv factors", "Hs gag biosynthesis", "Hs gag degradation", "Hsf1 activation", "Hsf1 dependent transactivation", "Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand", "Hur elavl1 binds and stabilizes mrna", "Hyaluronan metabolism", "Hyaluronan uptake and degradation", "Hydrolysis of lpc", "Ikba variant leads to eda id", "Ikk complex recruitment mediated by rip1", "Immunoregulatory interactions between a lymphoid and a non lymphoid cell", "Inactivation of cdc42 and rac1", "Inactivation of csf3 g csf signaling", "Incretin synthesis secretion and inactivation", "Infection with mycobacterium tuberculosis", "Infectious disease", "Inflammasomes", "Influenza infection", "Inhibition of dna recombination at telomere", "Inhibition of replication initiation of damaged dna by rb1 e2f1", "Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components", "Initiation of nuclear envelope ne reformation", "Inla mediated entry of listeria monocytogenes into host cells", "Inlb mediated entry of listeria monocytogenes into host cell", "Innate immune system", "Inositol phosphate metabolism", "Insertion of tail anchored proteins into the endoplasmic reticulum membrane", "Insulin processing", "Insulin receptor recycling", "Insulin receptor signalling cascade", "Integration of energy metabolism", "Integration of provirus", "Integrin cell surface interactions", "Integrin signaling", "Interaction between l1 and ankyrins", "Interaction with cumulus cells and the zona pellucida", "Interactions of rev with host cellular proteins", "Interactions of vpr with host cellular proteins", "Interconversion of nucleotide di and triphosphates", "Interferon alpha beta signaling", "Interferon gamma signaling", "Interferon signaling", "Interleukin 1 family signaling", "Interleukin 1 processing", "Interleukin 1 signaling", "Interleukin 10 signaling", "Interleukin 12 family signaling", "Interleukin 12 signaling", "Interleukin 15 signaling", "Interleukin 17 signaling", "Interleukin 2 family signaling", "Interleukin 20 family signaling", "Interleukin 21 signaling", "Interleukin 23 signaling", "Interleukin 27 signaling", "Interleukin 3 interleukin 5 and gm csf signaling", "Interleukin 35 signalling", "Interleukin 37 signaling", "Interleukin 4 and interleukin 13 signaling", "Interleukin 6 family signaling", "Interleukin 6 signaling", "Interleukin 7 signaling", "Interleukin 9 signaling", "Interleukin receptor shc signaling", "Intra golgi and retrograde golgi to er traffic", "Intra golgi traffic", "Intracellular signaling by second messengers", "Intraflagellar transport", "Intrinsic pathway for apoptosis", "Intrinsic pathway of fibrin clot formation", "Inwardly rectifying k channels", "Ion channel transport", "Ion homeostasis", "Ion transport by p type atpases", "Ionotropic activity of kainate receptors", "Irak1 recruits ikk complex", "Irak2 mediated activation of tak1 complex", "Irak4 deficiency tlr2 4", "Ire1alpha activates chaperones", "Irf3 mediated activation of type 1 ifn", "Irf3 mediated induction of type i ifn", "Iron uptake and transport", "Irs mediated signalling", "Jnk c jun kinases phosphorylation and activation mediated by activated human tak1", "Josephin domain dubs", "Keratan sulfate biosynthesis", "Keratan sulfate degradation", "Keratan sulfate keratin metabolism", "Keratinization", "Ketone body metabolism", "Killing mechanisms", "Kinesins", "Ksrp khsrp binds and destabilizes mrna", "L1cam interactions", "Lagging strand synthesis", "Laminin interactions", "Late endosomal microautophagy", "Ldl clearance", "Ldl remodeling", "Leishmania infection", "Lgi adam interactions", "Linoleic acid la metabolism", "Lipophagy", "Listeria monocytogenes entry into host cells", "Long term potentiation", "Loss of function of mecp2 in rett syndrome", "Loss of mecp2 binding ability to the ncor smrt complex", "Lrr flii interacting protein 1 lrrfip1 activates type i ifn production", "Lysine catabolism", "Lysosome vesicle biogenesis", "M phase", "Map2k and mapk activation", "Map3k8 tpl2 dependent mapk1 3 activation", "Mapk family signaling cascades", "Mapk targets nuclear events mediated by map kinases", "Mapk1 erk2 activation", "Mapk3 erk1 activation", "Mapk6 mapk4 signaling", "Mastl facilitates mitotic progression", "Maturation of protein 3a", "Maturation of sars cov 1 nucleoprotein", "Maturation of sars cov 1 spike protein", "Maturation of sars cov 2 nucleoprotein", "Maturation of sars cov 2 spike protein", "Mecp2 regulates neuronal receptors and channels", "Mecp2 regulates transcription factors", "Mecp2 regulates transcription of neuronal ligands", "Meiosis", "Meiotic recombination", "Meiotic synapsis", "Membrane trafficking", "Met activates pi3k akt signaling", "Met activates ptk2 signaling", "Met activates ptpn11", "Met activates rap1 and rac1", "Met activates ras signaling", "Met interacts with tns proteins", "Met promotes cell motility", "Met receptor activation", "Met receptor recycling", "Metabolic disorders of biological oxidation enzymes", "Metabolism of amino acids and derivatives", "Metabolism of angiotensinogen to angiotensins", "Metabolism of carbohydrates", "Metabolism of cofactors", "Metabolism of fat soluble vitamins", "Metabolism of folate and pterines", "Metabolism of ingested semet sec mesec into h2se", "Metabolism of lipids", "Metabolism of nitric oxide nos3 activation and regulation", "Metabolism of nucleotides", "Metabolism of polyamines", "Metabolism of porphyrins", "Metabolism of rna", "Metabolism of steroid hormones", "Metabolism of steroids", "Metabolism of vitamins and cofactors", "Metabolism of water soluble vitamins and cofactors", "Metal ion slc transporters", "Metalloprotease dubs", "Methionine salvage pathway", "Methylation", "Mhc class ii antigen presentation", "Microrna mirna biogenesis", "Miro gtpase cycle", "Miscellaneous transport and binding events", "Mismatch repair", "Mitochondrial biogenesis", "Mitochondrial calcium ion transport", "Mitochondrial fatty acid beta oxidation", "Mitochondrial fatty acid beta oxidation of saturated fatty acids", "Mitochondrial fatty acid beta oxidation of unsaturated fatty acids", "Mitochondrial iron sulfur cluster biogenesis", "Mitochondrial protein import", "Mitochondrial translation", "Mitochondrial trna aminoacylation", "Mitophagy", "Mitotic g1 phase and g1 s transition", "Mitotic g2 g2 m phases", "Mitotic metaphase and anaphase", "Mitotic prometaphase", "Mitotic prophase", "Mitotic spindle checkpoint", "Mitotic telophase cytokinesis", "Molecules associated with elastic fibres", "Molybdenum cofactor biosynthesis", "Mrna capping", "Mrna decay by 3 to 5 exoribonuclease", "Mrna decay by 5 to 3 exoribonuclease", "Mrna editing", "Mrna editing c to u conversion", "Mrna splicing", "Mrna splicing minor pathway", "Mtor signalling", "Mtorc1 mediated signalling", "Mucopolysaccharidoses", "Muscle contraction", "Myd88 independent tlr4 cascade", "Myoclonic epilepsy of lafora", "Myogenesis", "N glycan antennae elongation", "N glycan antennae elongation in the medial trans golgi", "N glycan trimming and elongation in the cis golgi", "N glycan trimming in the er and calnexin calreticulin cycle", "Na cl dependent neurotransmitter transporters", "Nade modulates death signalling", "Ncam signaling for neurite out growth", "Nectin necl trans heterodimerization", "Neddylation", "Nef and signal transduction", "Nef mediated cd4 down regulation", "Nef mediated cd8 down regulation", "Nef mediated downregulation of mhc class i complex cell surface expression", "Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters", "Negative epigenetic regulation of rrna expression", "Negative feedback regulation of mapk pathway", "Negative regulation of fgfr1 signaling", "Negative regulation of fgfr2 signaling", "Negative regulation of fgfr3 signaling", "Negative regulation of fgfr4 signaling", "Negative regulation of flt3", "Negative regulation of mapk pathway", "Negative regulation of met activity", "Negative regulation of nmda receptor mediated neuronal transmission", "Negative regulation of notch4 signaling", "Negative regulation of tcf dependent signaling by dvl interacting proteins", "Negative regulation of the pi3k akt network", "Negative regulators of ddx58 ifih1 signaling", "Nephrin family interactions", "Nervous system development", "Netrin 1 signaling", "Netrin mediated repulsion signals", "Neurexins and neuroligins", "Neurofascin interactions", "Neuronal system", "Neurotransmitter clearance", "Neurotransmitter receptors and postsynaptic signal transmission", "Neurotransmitter release cycle", "Neutrophil degranulation", "Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10", "Nf kb is activated and signals survival", "Ngf stimulated transcription", "Nicotinamide salvaging", "Nicotinate metabolism", "Nod1 2 signaling pathway", "Non integrin membrane ecm interactions", "Noncanonical activation of notch3", "Nonhomologous end joining nhej", "Nonsense mediated decay nmd", "Norepinephrine neurotransmitter release cycle", "Nostrin mediated enos trafficking", "Notch hlh transcription pathway", "Notch1 intracellular domain regulates transcription", "Notch2 activation and transmission of signal to the nucleus", "Notch3 activation and transmission of signal to the nucleus", "Notch3 intracellular domain regulates transcription", "Notch4 activation and transmission of signal to the nucleus", "Notch4 intracellular domain regulates transcription", "Nr1h2 and nr1h3 mediated signaling", "Nr1h2 nr1h3 regulate gene expression linked to lipogenesis", "Nr1h2 nr1h3 regulate gene expression to control bile acid homeostasis", "Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux", "Nrage signals death through jnk", "Nrcam interactions", "Nrif signals cell death from the nucleus", "Ns1 mediated effects on host pathways", "Ntrk2 activates rac1", "Nuclear envelope breakdown", "Nuclear envelope ne reassembly", "Nuclear events kinase and transcription factor activation", "Nuclear events stimulated by alk signaling in cancer", "Nuclear import of rev protein", "Nuclear pore complex npc disassembly", "Nuclear receptor transcription pathway", "Nuclear signaling by erbb4", "Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways", "Nucleotide biosynthesis", "Nucleotide catabolism", "Nucleotide excision repair", "Nucleotide salvage", "O linked glycosylation", "O linked glycosylation of mucins", "Oas antiviral response", "Oncogene induced senescence", "Oncogenic mapk signaling", "Opioid signalling", "Orc1 removal from chromatin", "Organelle biogenesis and maintenance", "Organic anion transporters", "Other interleukin signaling", "Other semaphorin interactions", "Ovarian tumor domain proteases", "Oxidative stress induced senescence", "P130cas linkage to mapk signaling for integrins", "P38mapk events", "P75 ntr receptor mediated signalling", "P75ntr negatively regulates cell cycle via sc1", "P75ntr recruits signalling complexes", "P75ntr regulates axonogenesis", "P75ntr signals via nf kb", "Parasite infection", "Passive transport by aquaporins", "Pcna dependent long patch base excision repair", "Pcp ce pathway", "Pd 1 signaling", "Pecam1 interactions", "Pentose phosphate pathway", "Peptide hormone metabolism", "Peptide ligand binding receptors", "Perk regulates gene expression", "Peroxisomal lipid metabolism", "Peroxisomal protein import", "Pexophagy", "Phase 0 rapid depolarisation", "Phase 2 plateau phase", "Phase 3 rapid repolarisation", "Phase i functionalization of compounds", "Phase ii conjugation of compounds", "Phenylalanine and tyrosine metabolism", "Phenylalanine metabolism", "Phosphate bond hydrolysis by nudt proteins", "Phospholipase c mediated cascade fgfr2", "Phospholipase c mediated cascade fgfr4", "Phospholipid metabolism", "Phosphorylation of emi1", "Phosphorylation of the apc c", "Pi 3k cascade fgfr1", "Pi 3k cascade fgfr2", "Pi 3k cascade fgfr3", "Pi 3k cascade fgfr4", "Pi metabolism", "Pi3k akt activation", "Pi3k akt signaling in cancer", "Pi3k events in erbb2 signaling", "Pi5p regulates tp53 acetylation", "Pink1 prkn mediated mitophagy", "Piwi interacting rna pirna biogenesis", "Pka activation in glucagon signalling", "Pka mediated phosphorylation of creb", "Pka mediated phosphorylation of key metabolic factors", "Pkmts methylate histone lysines", "Plasma lipoprotein assembly", "Plasma lipoprotein assembly remodeling and clearance", "Plasma lipoprotein clearance", "Plasma lipoprotein remodeling", "Platelet activation signaling and aggregation", "Platelet adhesion to exposed collagen", "Platelet aggregation plug formation", "Platelet calcium homeostasis", "Platelet homeostasis", "Platelet sensitization by ldl", "Polb dependent long patch base excision repair", "Polo like kinase mediated events", "Polymerase switching", "Polymerase switching on the c strand of the telomere", "Positive epigenetic regulation of rrna expression", "Post chaperonin tubulin folding pathway", "Post translational modification synthesis of gpi anchored proteins", "Post translational protein modification", "Postmitotic nuclear pore complex npc reformation", "Potassium channels", "Potential therapeutics for sars", "Pou5f1 oct4 sox2 nanog activate genes related to proliferation", "Pou5f1 oct4 sox2 nanog repress genes related to differentiation", "Pp2a mediated dephosphorylation of key metabolic factors", "Prc2 methylates histones and dna", "Pre notch expression and processing", "Pre notch processing in golgi", "Pre notch processing in the endoplasmic reticulum", "Pregnenolone biosynthesis", "Presynaptic function of kainate receptors", "Prevention of phagosomal lysosomal fusion", "Processing and activation of sumo", "Processing of capped intron containing pre mrna", "Processing of capped intronless pre mrna", "Processing of dna double strand break ends", "Processing of intronless pre mrnas", "Processing of smdt1", "Processive synthesis on the c strand of the telomere", "Processive synthesis on the lagging strand", "Programmed cell death", "Prolactin receptor signaling", "Prolonged erk activation events", "Propionyl coa catabolism", "Prostacyclin signalling through prostacyclin receptor", "Protein folding", "Protein localization", "Protein methylation", "Protein protein interactions at synapses", "Protein repair", "Protein ubiquitination", "Proton coupled monocarboxylate transport", "Pten regulation", "Ptk6 expression", "Ptk6 promotes hif1a stabilization", "Ptk6 regulates cell cycle", "Ptk6 regulates proteins involved in rna processing", "Ptk6 regulates rho gtpases ras gtpase and map kinases", "Ptk6 regulates rtks and their effectors akt1 and dok1", "Purine catabolism", "Purine ribonucleoside monophosphate biosynthesis", "Purine salvage", "Purinergic signaling in leishmaniasis infection", "Pyrimidine catabolism", "Pyrimidine salvage", "Pyroptosis", "Pyruvate metabolism", "Pyruvate metabolism and citric acid tca cycle", "Ra biosynthesis pathway", "Rab gefs exchange gtp for gdp on rabs", "Rab geranylgeranylation", "Rab regulation of trafficking", "Rac1 gtpase cycle", "Rac2 gtpase cycle", "Rac3 gtpase cycle", "Raf activation", "Raf independent mapk1 3 activation", "Rap1 signalling", "Ras activation upon ca2 influx through nmda receptor", "Ras processing", "Reactions specific to the complex n glycan synthesis pathway", "Receptor mediated mitophagy", "Receptor type tyrosine protein phosphatases", "Recognition and association of dna glycosylase with site containing an affected purine", "Recognition of dna damage by pcna containing replication complex", "Recruitment of mitotic centrosome proteins and complexes", "Recruitment of numa to mitotic centrosomes", "Recycling of eif2 gdp", "Recycling pathway of l1", "Reduction of cytosolic ca levels", "Regulated necrosis", "Regulated proteolysis of p75ntr", "Regulation by c flip", "Regulation of bach1 activity", "Regulation of beta cell development", "Regulation of cholesterol biosynthesis by srebp srebf", "Regulation of commissural axon pathfinding by slit and robo", "Regulation of cytoskeletal remodeling and cell spreading by ipp complex components", "Regulation of expression of slits and robos", "Regulation of foxo transcriptional activity by acetylation", "Regulation of gene expression in beta cells", "Regulation of gene expression in late stage branching morphogenesis pancreatic bud precursor cells", "Regulation of glucokinase by glucokinase regulatory protein", "Regulation of glycolysis by fructose 2 6 bisphosphate metabolism", "Regulation of hmox1 expression and activity", "Regulation of hsf1 mediated heat shock response", "Regulation of ifna signaling", "Regulation of ifng signaling", "Regulation of innate immune responses to cytosolic dna", "Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps", "Regulation of insulin secretion", "Regulation of kit signaling", "Regulation of lipid metabolism by pparalpha", "Regulation of localization of foxo transcription factors", "Regulation of mecp2 expression and activity", "Regulation of mrna stability by proteins that bind au rich elements", "Regulation of plk1 activity at g2 m transition", "Regulation of pten gene transcription", "Regulation of pten localization", "Regulation of pten mrna translation", "Regulation of pten stability and activity", "Regulation of pyruvate dehydrogenase pdh complex", "Regulation of ras by gaps", "Regulation of runx1 expression and activity", "Regulation of runx2 expression and activity", "Regulation of runx3 expression and activity", "Regulation of signaling by cbl", "Regulation of tlr by endogenous ligand", "Regulation of tnfr1 signaling", "Regulation of tp53 activity", "Regulation of tp53 activity through acetylation", "Regulation of tp53 activity through association with co factors", "Regulation of tp53 activity through methylation", "Regulation of tp53 activity through phosphorylation", "Regulation of tp53 expression and degradation", "Release of apoptotic factors from the mitochondria", "Release of hh np from the secreting cell", "Repression of wnt target genes", "Reproduction", "Resolution of abasic sites ap sites", "Resolution of ap sites via the multiple nucleotide patch replacement pathway", "Resolution of d loop structures", "Resolution of d loop structures through synthesis dependent strand annealing sdsa", "Resolution of sister chromatid cohesion", "Respiratory electron transport", "Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins", "Response of eif2ak1 hri to heme deficiency", "Response of eif2ak4 gcn2 to amino acid deficiency", "Response of mtb to phagocytosis", "Response to elevated platelet cytosolic ca2", "Ret signaling", "Retrograde neurotrophin signalling", "Retrograde transport at the trans golgi network", "Rho gtpase cycle", "Rho gtpase effectors", "Rho gtpases activate cit", "Rho gtpases activate formins", "Rho gtpases activate iqgaps", "Rho gtpases activate ktn1", "Rho gtpases activate nadph oxidases", "Rho gtpases activate paks", "Rho gtpases activate pkns", "Rho gtpases activate rhotekin and rhophilins", "Rho gtpases activate rocks", "Rho gtpases activate wasps and waves", "Rhoa gtpase cycle", "Rhob gtpase cycle", "Rhobtb gtpase cycle", "Rhobtb1 gtpase cycle", "Rhobtb2 gtpase cycle", "Rhobtb3 atpase cycle", "Rhoc gtpase cycle", "Rhod gtpase cycle", "Rhof gtpase cycle", "Rhog gtpase cycle", "Rhoh gtpase cycle", "Rhoj gtpase cycle", "Rhoq gtpase cycle", "Rhot1 gtpase cycle", "Rhou gtpase cycle", "Rhov gtpase cycle", "Rip mediated nfkb activation via zbp1", "Ripk1 mediated regulated necrosis", "Rmts methylate histone arginines", "Rna polymerase i promoter escape", "Rna polymerase i transcription", "Rna polymerase i transcription initiation", "Rna polymerase i transcription termination", "Rna polymerase ii transcribes snrna genes", "Rna polymerase ii transcription", "Rna polymerase ii transcription termination", "Rna polymerase iii chain elongation", "Rna polymerase iii transcription", "Rna polymerase iii transcription initiation from type 1 promoter", "Rna polymerase iii transcription initiation from type 3 promoter", "Rna polymerase iii transcription termination", "Rnd1 gtpase cycle", "Rnd2 gtpase cycle", "Rnd3 gtpase cycle", "Robo receptors bind akap5", "Role of abl in robo slit signaling", "Role of lat2 ntal lab on calcium mobilization", "Role of phospholipids in phagocytosis", "Role of second messengers in netrin 1 signaling", "Rora activates gene expression", "Ros and rns production in phagocytes", "Rrna modification in the mitochondrion", "Rrna modification in the nucleus and cytosol", "Rrna processing", "Rrna processing in the mitochondrion", "Rsk activation", "Runx1 interacts with co factors whose precise effect on runx1 targets is not known", "Runx1 regulates estrogen receptor mediated transcription", "Runx1 regulates expression of components of tight junctions", "Runx1 regulates genes involved in megakaryocyte differentiation and platelet function", "Runx1 regulates transcription of genes involved in differentiation of hscs", "Runx2 regulates bone development", "Runx2 regulates genes involved in cell migration", "Runx2 regulates osteoblast differentiation", "Runx3 regulates cdkn1a transcription", "Runx3 regulates notch signaling", "Runx3 regulates p14 arf", "Runx3 regulates wnt signaling", "Runx3 regulates yap1 mediated transcription", "S phase", "Sars cov 1 infection", "Sars cov 2 infection", "Sars cov infections", "Scavenging by class a receptors", "Scavenging by class b receptors", "Scavenging by class f receptors", "Scavenging of heme from plasma", "Scf skp2 mediated degradation of p27 p21", "Sealing of the nuclear envelope ne by escrt iii", "Selective autophagy", "Selenoamino acid metabolism", "Sema3a pak dependent axon repulsion", "Sema3a plexin repulsion signaling by inhibiting integrin adhesion", "Sema4d in semaphorin signaling", "Sema4d induced cell migration and growth cone collapse", "Sema4d mediated inhibition of cell attachment and migration", "Semaphorin interactions", "Senescence associated secretory phenotype sasp", "Sensing of dna double strand breaks", "Sensory perception", "Sensory processing of sound", "Sensory processing of sound by outer hair cells of the cochlea", "Separation of sister chromatids", "Serine biosynthesis", "Serotonin neurotransmitter release cycle", "Shc mediated cascade fgfr1", "Shc mediated cascade fgfr3", "Shc mediated cascade fgfr4", "Shc related events triggered by igf1r", "Shc1 events in egfr signaling", "Shc1 events in erbb2 signaling", "Shc1 events in erbb4 signaling", "Sialic acid metabolism", "Signal amplification", "Signal attenuation", "Signal regulatory protein family interactions", "Signal transduction by l1", "Signaling by activin", "Signaling by alk", "Signaling by alk in cancer", "Signaling by bmp", "Signaling by braf and raf1 fusions", "Signaling by csf3 g csf", "Signaling by ctnnb1 phospho site mutants", "Signaling by cytosolic fgfr1 fusion mutants", "Signaling by egfr", "Signaling by egfr in cancer", "Signaling by erbb2", "Signaling by erbb2 ecd mutants", "Signaling by erbb2 in cancer", "Signaling by erbb4", "Signaling by erythropoietin", "Signaling by fgfr", "Signaling by fgfr in disease", "Signaling by fgfr1", "Signaling by fgfr1 in disease", "Signaling by fgfr2", "Signaling by fgfr2 iiia tm", "Signaling by fgfr2 in disease", "Signaling by fgfr3", "Signaling by fgfr3 fusions in cancer", "Signaling by fgfr4", "Signaling by fgfr4 in disease", "Signaling by flt3 fusion proteins", "Signaling by flt3 itd and tkd mutants", "Signaling by gpcr", "Signaling by hedgehog", "Signaling by hippo", "Signaling by insulin receptor", "Signaling by interleukins", "Signaling by kit in disease", "Signaling by leptin", "Signaling by mapk mutants", "Signaling by met", "Signaling by moderate kinase activity braf mutants", "Signaling by mras complex mutants", "Signaling by mst1", "Signaling by nodal", "Signaling by notch", "Signaling by notch1", "Signaling by notch1 hd domain mutants in cancer", "Signaling by notch1 pest domain mutants in cancer", "Signaling by notch1 t 7 9 notch1 m1580 k2555 translocation mutant", "Signaling by notch2", "Signaling by notch3", "Signaling by notch4", "Signaling by ntrk2 trkb", "Signaling by ntrk3 trkc", "Signaling by ntrks", "Signaling by nuclear receptors", "Signaling by pdgf", "Signaling by pdgfr in disease", "Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants", "Signaling by ptk6", "Signaling by receptor tyrosine kinases", "Signaling by retinoic acid", "Signaling by rho gtpases miro gtpases and rhobtb3", "Signaling by robo receptors", "Signaling by scf kit", "Signaling by tgf beta receptor complex", "Signaling by tgf beta receptor complex in cancer", "Signaling by tgfb family members", "Signaling by the b cell receptor bcr", "Signaling by type 1 insulin like growth factor 1 receptor igf1r", "Signaling by vegf", "Signaling by wnt", "Signaling by wnt in cancer", "Signalling to erks", "Signalling to ras", "Sirt1 negatively regulates rrna expression", "Slbp dependent processing of replication dependent histone pre mrnas", "Slc mediated transmembrane transport", "Slc transporter disorders", "Smac xiap regulated apoptotic response", "Smad2 smad3 smad4 heterotrimer regulates transcription", "Small interfering rna sirna biogenesis", "Smooth muscle contraction", "Snrnp assembly", "Sodium calcium exchangers", "Sos mediated signalling", "Sphingolipid de novo biosynthesis", "Sphingolipid metabolism", "Spry regulation of fgf signaling", "Srp dependent cotranslational protein targeting to membrane", "Stabilization of p53", "Stat3 nuclear events downstream of alk signaling", "Stat5 activation", "Stat5 activation downstream of flt3 itd mutants", "Stimuli sensing channels", "Sting mediated induction of host immune responses", "Striated muscle contraction", "Sulfide oxidation to sulfate", "Sulfur amino acid metabolism", "Sumo is conjugated to e1 uba2 sae1", "Sumo is proteolytically processed", "Sumo is transferred from e1 to e2 ube2i ubc9", "Sumoylation", "Sumoylation of chromatin organization proteins", "Sumoylation of dna damage response and repair proteins", "Sumoylation of dna methylation proteins", "Sumoylation of dna replication proteins", "Sumoylation of immune response proteins", "Sumoylation of intracellular receptors", "Sumoylation of rna binding proteins", "Sumoylation of sumoylation proteins", "Sumoylation of transcription cofactors", "Sumoylation of transcription factors", "Sumoylation of ubiquitinylation proteins", "Suppression of apoptosis", "Suppression of phagosomal maturation", "Surfactant metabolism", "Switching of origins to a post replicative state", "Synaptic adhesion like molecules", "Syndecan interactions", "Synthesis of 5 eicosatetraenoic acids", "Synthesis of active ubiquitin roles of e1 and e2 enzymes", "Synthesis of bile acids and bile salts", "Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol", "Synthesis of diphthamide eef2", "Synthesis of dna", "Synthesis of dolichyl phosphate", "Synthesis of epoxy eet and dihydroxyeicosatrienoic acids dhet", "Synthesis of gdp mannose", "Synthesis of glycosylphosphatidylinositol gpi", "Synthesis of ip2 ip and ins in the cytosol", "Synthesis of ip3 and ip4 in the cytosol", "Synthesis of ketone bodies", "Synthesis of leukotrienes lt and eoxins ex", "Synthesis of lipoxins lx", "Synthesis of pa", "Synthesis of pc", "Synthesis of pe", "Synthesis of pg", "Synthesis of pi", "Synthesis of pips at the early endosome membrane", "Synthesis of pips at the er membrane", "Synthesis of pips at the golgi membrane", "Synthesis of pips at the late endosome membrane", "Synthesis of pips at the plasma membrane", "Synthesis of prostaglandins pg and thromboxanes tx", "Synthesis of pyrophosphates in the cytosol", "Synthesis of substrates in n glycan biosythesis", "Synthesis of udp n acetyl glucosamine", "Synthesis of very long chain fatty acyl coas", "Synthesis secretion and deacylation of ghrelin", "Synthesis secretion and inactivation of glucagon like peptide 1 glp 1", "Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip", "Tak1 activates nfkb by phosphorylation and activation of ikks complex", "Tbc rabgaps", "Tcf dependent signaling in response to wnt", "Tcr signaling", "Telomere c strand lagging strand synthesis", "Telomere c strand synthesis initiation", "Telomere extension by telomerase", "Telomere maintenance", "Terminal pathway of complement", "Termination of translesion dna synthesis", "Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation", "Tfap2 ap 2 family regulates transcription of growth factors and their receptors", "Tfap2a acts as a transcriptional repressor during retinoic acid induced cell differentiation", "Tgf beta receptor signaling activates smads", "Tgf beta receptor signaling in emt epithelial to mesenchymal transition", "The activation of arylsulfatases", "The canonical retinoid cycle in rods twilight vision", "The citric acid tca cycle and respiratory electron transport", "The nlrp3 inflammasome", "The phototransduction cascade", "The role of gtse1 in g2 m progression after g2 checkpoint", "The role of nef in hiv 1 replication and disease pathogenesis", "Thrombin signalling through proteinase activated receptors pars", "Thromboxane signalling through tp receptor", "Ticam1 dependent activation of irf3 irf7", "Ticam1 rip1 mediated ikk complex recruitment", "Ticam1 traf6 dependent induction of tak1 complex", "Tie2 signaling", "Tight junction interactions", "Tlr3 mediated ticam1 dependent programmed cell death", "Tnf signaling", "Tnfr1 induced nfkappab signaling pathway", "Tnfr1 induced proapoptotic signaling", "Tnfr1 mediated ceramide production", "Tnfr2 non canonical nf kb pathway", "Toll like receptor 9 tlr9 cascade", "Toll like receptor cascades", "Toll like receptor tlr1 tlr2 cascade", "Tp53 regulates metabolic genes", "Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain", "Tp53 regulates transcription of caspase activators and caspases", "Tp53 regulates transcription of cell cycle genes", "Tp53 regulates transcription of cell death genes", "Tp53 regulates transcription of death receptors and ligands", "Tp53 regulates transcription of dna repair genes", "Tp53 regulates transcription of genes involved in cytochrome c release", "Tp53 regulates transcription of genes involved in g1 cell cycle arrest", "Tp53 regulates transcription of genes involved in g2 cell cycle arrest", "Tp53 regulates transcription of several additional cell death genes whose specific roles in p53 dependent apoptosis remain uncertain", "Traf3 dependent irf activation pathway", "Traf6 mediated induction of tak1 complex within tlr4 complex", "Traf6 mediated irf7 activation", "Traf6 mediated irf7 activation in tlr7 8 or 9 signaling", "Traf6 mediated nf kb activation", "Trafficking and processing of endosomal tlr", "Trafficking of ampa receptors", "Trafficking of glur2 containing ampa receptors", "Trafficking of myristoylated proteins to the cilium", "Trans golgi network vesicle budding", "Transcription coupled nucleotide excision repair tc ner", "Transcription of e2f targets under negative control by dream complex", "Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1", "Transcription of the hiv genome", "Transcriptional activation of mitochondrial biogenesis", "Transcriptional activity of smad2 smad3 smad4 heterotrimer", "Transcriptional regulation by e2f6", "Transcriptional regulation by mecp2", "Transcriptional regulation by runx1", "Transcriptional regulation by runx2", "Transcriptional regulation by runx3", "Transcriptional regulation by small rnas", "Transcriptional regulation by the ap 2 tfap2 family of transcription factors", "Transcriptional regulation by tp53", "Transcriptional regulation by ventx", "Transcriptional regulation of granulopoiesis", "Transcriptional regulation of pluripotent stem cells", "Transcriptional regulation of white adipocyte differentiation", "Transferrin endocytosis and recycling", "Translation", "Translation of replicase and assembly of the replication transcription complex", "Translation of sars cov 1 structural proteins", "Translation of sars cov 2 structural proteins", "Translesion synthesis by polh", "Translesion synthesis by polk", "Translesion synthesis by y family dna polymerases bypasses lesions on dna template", "Translocation of slc2a4 glut4 to the plasma membrane", "Transmission across chemical synapses", "Transport and synthesis of paps", "Transport of bile salts and organic acids metal ions and amine compounds", "Transport of connexons to the plasma membrane", "Transport of fatty acids", "Transport of inorganic cations anions and amino acids oligopeptides", "Transport of mature mrnas derived from intronless transcripts", "Transport of mature transcript to cytoplasm", "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane", "Transport of nucleotide sugars", "Transport of small molecules", "Transport of the slbp dependant mature mrna", "Transport of vitamins nucleosides and related molecules", "Transport to the golgi and subsequent modification", "Trif mediated programmed cell death", "Triglyceride biosynthesis", "Triglyceride catabolism", "Triglyceride metabolism", "Tristetraprolin ttp zfp36 binds and destabilizes mrna", "Trna aminoacylation", "Trna modification in the mitochondrion", "Trna modification in the nucleus and cytosol", "Trna processing", "Trna processing in the mitochondrion", "Trna processing in the nucleus", "Trp channels", "Tryptophan catabolism", "Type i hemidesmosome assembly", "Tyrosine catabolism", "Tysnd1 cleaves peroxisomal proteins", "Ub specific processing proteases", "Uch proteinases", "Unblocking of nmda receptors glutamate binding and activation", "Unfolded protein response upr", "Unwinding of dna", "Uptake and actions of bacterial toxins", "Uptake and function of anthrax toxins", "Uptake and function of diphtheria toxin", "Urea cycle", "Vasopressin regulates renal water homeostasis via aquaporins", "Vegfr2 mediated cell proliferation", "Vegfr2 mediated vascular permeability", "Vesicle mediated transport", "Viral messenger rna synthesis", "Visual phototransduction", "Vitamin b2 riboflavin metabolism", "Vitamin b5 pantothenate metabolism", "Vitamin c ascorbate metabolism", "Vitamin d calciferol metabolism", "Vldl assembly", "Vldlr internalisation and degradation", "Vxpx cargo targeting to cilium", "Wax and plasmalogen biosynthesis", "Wnt ligand biogenesis and trafficking", "Wnt mediated activation of dvl", "Wnt5a dependent internalization of fzd2 fzd5 and ror2", "Wnt5a dependent internalization of fzd4", "Yap1 and wwtr1 taz stimulated gene expression", "Zbp1 dai mediated induction of type i ifns", "Zinc efflux and compartmentalization by the slc30 family", "Zinc transporters"], "available_proteins": ["AAAS", "AACS", "AAK1", "AAMP", "AARS", "AARS2", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAM17", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AHCYL1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP9", "AKR1A1", "AKR1B1", "AKT1", "AKT1S1", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG13", "ALG5", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANLN", "ANXA1", "ANXA2", "ANXA6", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "APC", "APEH", "APEX1", "APOBEC3C", "APOO", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP3", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGAP35", "ARHGAP5", "ARHGDIA", "ARHGEF2", "ARID1A", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6", "ARL6IP5", "ARMCX3", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASB6", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD3B", "ATF7IP", "ATG3", "ATG4B", "ATG9A", "ATIC", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATRX", "B3GALT6", "B4GALT1", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAX", "BAZ1B", "BCAP31", "BCAS2", "BCAT2", "BCS1L", "BDH2", "BICD2", "BIRC6", "BLM", "BLMH", "BLOC1S1", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BRAP", "BRCA1", "BRD2", "BRD4", "BSG", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "C19orf70", "C1QBP", "C1orf35", "C2CD5", "C2orf49", "CAB39", "CAD", "CADM1", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CANX", "CAP1", "CAP2", "CAPN1", "CAPN2", "CAPNS1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CASP2", "CASP3", "CAST", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC22", "CCDC88A", "CCNA2", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC23", "CDC25C", "CDC27", "CDC37", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC73", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK4", "CDK5", "CDK6", "CDKAL1", "CDKN2A", "CDS2", "CDX2", "CENPE", "CENPI", "CENPU", "CEP250", "CERS2", "CETN2", "CFL1", "CHAC2", "CHAF1B", "CHAMP1", "CHCHD3", "CHCHD4", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP4A", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHP1", "CHST14", "CHTF18", "CHTF8", "CHTOP", "CHUK", "CIAPIN1", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLINT1", "CLNS1A", "CLSPN", "CLTA", "CLTC", "CLU", "CMAS", "CMBL", "CMPK1", "CNDP2", "CNN2", "CNOT1", "CNOT11", "CNOT3", "CNOT7", "CNOT9", "COASY", "COG2", "COG3", "COG4", "COG7", "COLEC12", "COLGALT1", "COMMD1", "COMMD10", "COMMD2", "COMMD7", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COTL1", "COX11", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRK", "CRKL", "CRNKL1", "CRTAP", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC15", "CWC22", "CYB5B", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAXX", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF7", "DCAF8", "DCD", "DCP1A", "DCP1B", "DCP2", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX52", "DDX56", "DDX6", "DEK", "DENND4C", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHODH", "DHPS", "DHRS4", "DHRS7B", "DHX15", "DHX16", "DHX36", "DHX37", "DHX38", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNA2", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB11", "DNAJC11", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK7", "DOHH", "DOLPP1", "DPH2", "DPH5", "DPM1", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DSC3", "DSG2", "DSP", "DST", "DTL", "DTYMK", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFTUD2", "EGFR", "EGLN1", "EHD1", "EHMT2", "EIF2AK2", "EIF2AK4", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP4", "EMC3", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENSA", "EPB41", "EPB41L2", "EPB41L5", "EPHX1", "EPHX2", "EPN1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERBIN", "ERCC2", "ERCC3", "ERCC6L", "ERI1", "ERLIN1", "ERLIN2", "ERO1A", "ERP44", "ESD", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXTL3", "EZR", "F11R", "FABP5", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM49B", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FAU", "FBL", "FBXO22", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FIP1L1", "FIS1", "FKBP14", "FKBP1A", "FKBP4", "FKBP5", "FKBP8", "FLAD1", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FNTA", "FNTB", "FSCN1", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FUS", "FXR1", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GEMIN8", "GET4", "GFM1", "GFPT1", "GGA1", "GGCT", "GGCX", "GGH", "GGT7", "GHDC", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GM2A", "GMDS", "GMPPA", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNE", "GNG5", "GNL3", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM1", "GOPC", "GORASP2", "GOT1", "GOT2", "GPAM", "GPD2", "GPHN", "GPI", "GPKOW", "GPS1", "GPSM1", "GPT2", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GSDME", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP3", "GTSE1", "GUSB", "GYG1", "GYS1", "H1F0", "H2AFX", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAGH", "HARS2", "HAT1", "HAUS1", "HAUS2", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HEBP1", "HECTD1", "HERC4", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HM13", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGCL", "HMGCS1", "HMGN1", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA6", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTT", "HUS1", "HUWE1", "HYOU1", "IARS", "IARS2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFNGR1", "IFT27", "IFT88", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IKBKB", "IKBKG", "ILF2", "ILK", "IMMT", "IMP3", "IMPA1", "IMPAD1", "IMPDH1", "IMPDH2", "INCENP", "INPP4A", "INTS1", "INTS11", "INTS12", "INTS13", "INTS14", "INTS3", "INTS7", "INTS9", "IPO5", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRS4", "ISCU", "ISG20L2", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITSN2", "IVD", "IWS1", "JMJD6", "JUP", "KARS", "KAT7", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0391", "KIF11", "KIF14", "KIF15", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRR1", "KTN1", "L2HGDH", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LARS", "LARS2", "LAS1L", "LBR", "LCMT1", "LDHA", "LDHB", "LDLR", "LDLRAP1", "LEMD2", "LEMD3", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LNPEP", "LPCAT1", "LPGAT1", "LRP1", "LRPPRC", "LRRC1", "LRRC41", "LSM2", "LSM6", "LSS", "LTA4H", "LTN1", "LTV1", "LYPLA1", "LZTFL1", "M6PR", "MAD1L1", "MAGED1", "MAGED2", "MAGT1", "MAIP1", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP2K1", "MAP2K3", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MARC1", "MARCKS", "MARS", "MAT2A", "MAT2B", "MAVS", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDC1", "MDH1", "MDH2", "ME2", "MEAF6", "MECP2", "MED1", "MED14", "MED16", "MED21", "MED23", "MED24", "MED4", "METAP1", "METAP2", "METTL1", "METTL3", "MFAP1", "MFN1", "MFN2", "MGAT1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINPP1", "MIPEP", "MLEC", "MMAB", "MMGT1", "MMS19", "MOGS", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP7", "MPRIP", "MPST", "MRC2", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL22", "MRPL23", "MRPL28", "MRPL3", "MRPL37", "MRPL39", "MRPL4", "MRPL40", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL50", "MRPL55", "MRPL58", "MRPL9", "MRPS10", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MSH2", "MSH3", "MSH6", "MSI1", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTERF3", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR2", "MTOR", "MTR", "MTX1", "MTX2", "MUT", "MVK", "MYBBP1A", "MYDGF", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1C", "MYO6", "NAA16", "NAA35", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAPA", "NAPG", "NARS", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCKAP1", "NCL", "NCOR1", "NCSTN", "ND5", "NDC1", "NDC80", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEFL", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NFKB1", "NFS1", "NHLRC2", "NHP2", "NIP7", "NIPBL", "NISCH", "NIT2", "NLN", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOB1", "NOC2L", "NOC4L", "NOL11", "NOL6", "NOL9", "NOP14", "NOP2", "NOP56", "NOP58", "NOSIP", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSUN2", "NSUN6", "NT5C2", "NT5C3A", "NT5C3B", "NUB1", "NUBPL", "NUCB1", "NUDC", "NUDT1", "NUDT12", "NUDT16", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NXF1", "OAT", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD7B", "OXA1L", "OXCT1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAK1", "PAK2", "PAK4", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PATL1", "PAXIP1", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNT", "PDAP1", "PDCD11", "PDCD6", "PDCD6IP", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA5", "PDIA6", "PDK3", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXK", "PEBP1", "PECR", "PELP1", "PES1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN1", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF2", "PHF5A", "PHF8", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIK3C2A", "PIK3C3", "PIK3R4", "PIN1", "PIP4K2B", "PIR", "PISD", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLCB3", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPO", "POFUT1", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAT", "PPFIA1", "PPIB", "PPID", "PPIE", "PPIH", "PPIL1", "PPIL3", "PPIL4", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R2", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKAR2B", "PRKCD", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSPH", "PTBP1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPN1", "PTPN11", "PTPN23", "PTPN9", "PTPRF", "PTRH2", "PUF60", "PUM1", "PUS1", "PUS7", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABEP1", "RABEPK", "RABGAP1", "RABGGTA", "RABGGTB", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAE1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RANGRF", "RAP1GDS1", "RAPGEF2", "RARS", "RARS2", "RBBP5", "RBBP6", "RBBP7", "RBM14", "RBM17", "RBM22", "RBM28", "RBM4", "RBM5", "RBM8A", "RBMX", "RCC1", "RCC2", "RCL1", "RCN1", "RDH11", "RDH13", "RDH14", "RDX", "REPS1", "REXO2", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RINT1", "RIOX2", "RIPK1", "RNASET2", "RNF14", "RNF20", "RNF220", "RNF40", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP8", "RRP9", "RSF1", "RSU1", "RTCB", "RTF1", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCO1", "SCO2", "SCP2", "SCRIB", "SDCBP", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEH1L", "SEL1L", "SENP3", "SEPT2", "SEPT7", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD7", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SGPL1", "SGTA", "SH3GL1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIN3A", "SIRT1", "SKA1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A22", "SLC25A26", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC30A7", "SLC35B2", "SLC38A2", "SLC3A2", "SLC6A15", "SLIT2", "SLK", "SLTM", "SLU7", "SMARCA4", "SMARCA5", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC6", "SMG8", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SNAP23", "SNAP29", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX2", "SNX3", "SNX5", "SNX9", "SOAT1", "SOD2", "SORD", "SORT1", "SPAG9", "SPC24", "SPC25", "SPCS2", "SPDL1", "SPEN", "SPHK2", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3NL", "STARD7", "STAT1", "STAT3", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRN", "STT3A", "STUB1", "STX18", "STX4", "STX6", "STXBP2", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUZ12", "SYMPK", "SYNE1", "SYNE2", "TAB1", "TACC3", "TACO1", "TADA3", "TAF15", "TAGLN2", "TALDO1", "TAP1", "TARS", "TARS2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D17", "TBC1D4", "TBC1D8B", "TBCA", "TBCB", "TBCC", "TBCD", "TBCE", "TBK1", "TBL1XR1", "TBL3", "TCEA1", "TCP1", "TDRKH", "TECR", "TERF2", "TERF2IP", "TEX10", "TEX264", "TFAM", "TFB1M", "TFG", "TFIP11", "TFRC", "TGS1", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM17A", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TIMM9", "TIMMDC1", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLN1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM11", "TMEM126B", "TMEM30A", "TMEM59", "TMEM63A", "TMEM87A", "TMF1", "TMLHE", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMX3", "TNKS1BP1", "TNPO1", "TOLLIP", "TOM1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1AIP1", "TOR1B", "TP53", "TP53BP1", "TPD52", "TPI1", "TPM1", "TPM3", "TPM4", "TPMT", "TPP1", "TPP2", "TPR", "TPX2", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIO", "TRIP12", "TRMT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT6", "TRMU", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPO", "TSR1", "TTC26", "TTC37", "TTLL12", "TTYH3", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXN2", "TXNDC5", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE2T", "UBE3A", "UBE3C", "UBE4A", "UBQLN1", "UBQLN2", "UBR1", "UBR4", "UBTF", "UBXN1", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119B", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USO1", "USP10", "USP11", "USP14", "USP15", "USP24", "USP28", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "UXT", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VKORC1L1", "VPS25", "VPS26A", "VPS29", "VPS33B", "VPS35", "VPS37C", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK2", "VTA1", "VTI1B", "WAPL", "WARS", "WARS2", "WASL", "WBP11", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR4", "WDR43", "WDR45B", "WDR46", "WDR48", "WDR5", "WDR6", "WDR61", "WDR75", "WDR77", "WDR91", "WFS1", "WIPI2", "WNK1", "WNK2", "WRAP53", "WTAP", "XAB2", "XPO1", "XPO5", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YAP1", "YARS", "YARS2", "YBX1", "YEATS2", "YEATS4", "YIF1A", "YKT6", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZC3H11A", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCRB1", "ZFYVE16", "ZMYM2", "ZNF512B", "ZNF638", "ZSWIM8", "ZW10", "ZWILCH"], "leading_proteins": ["ABCB1", "ABHD10", "ABHD12", "ACAT2", "ACBD5", "ACOT8", "ACOX1", "ACP6", "ACTN1", "ADAM17", "ADD1", "ADD3", "AHCYL1", "AKAP9", "AKT1", "ALDH1A2", "ALDH3A2", "ALKBH5", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANKLE2", "ANXA1", "AP1M1", "APOO", "ARF4", "ARF5", "ARFIP2", "ARL2", "ASAH1", "ASCC2", "ASCC3", "ASNS", "ATP13A1", "ATP13A2", "ATP2A2", "ATP5L", "ATP6", "ATP6V0A1", "ATP6V0A2", "B4GALT1", "B4GAT1", "BAG4", "BAG6", "BAIAP2", "BSG", "BUB1", "BUB1B", "C19orf70", "CAMK1", "CAPN2", "CARM1", "CASK", "CASP3", "CCNA2", "CCT2", "CCT5", "CDC42", "CDCA8", "CDK1", "CDK5", "CDKAL1", "CDKN2A", "CDS2", "CENPE", "CERS2", "CHCHD3", "CHCHD4", "CHEK1", "CHKA", "CHST14", "CHTF8", "CHUK", "CKAP4", "CLU", "CMBL", "COG3", "COLEC12", "COMT", "COPS3", "COX5A", "CPD", "CPNE1", "CPT2", "CRK", "CRTAP", "CSK", "CSNK1A1", "CSNK2B", "CTNNA1", "CTNNB1", "CTPS1", "CTSA", "CTSB", "CYB5B", "CYFIP1", "CYP51A1", "DCAF8", "DCTN2", "DCTPP1", "DCUN1D5", "DERL1", "DHCR24", "DHCR7", "DHFR", "DHRS4", "DIABLO", "DNA2", "DOLPP1", "DVL2", "EBP", "ECE1", "ECI1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF4E", "EMD", "ENDOD1", "EPHX1", "ERAP1", "ETFDH", "EXO1", "EXOC5", "EXTL3", "FABP5", "FAM114A2", "FAM49B", "FASN", "FDFT1", "FGFR1OP", "FIP1L1", "FKBP14", "FKBP1A", "FKBP4", "FKBP5", "FNTB", "FTO", "FUCA2", "FXR1", "GAA", "GBA", "GBE1", "GFPT1", "GGCX", "GGT7", "GLA", "GLUD1", "GM2A", "GMPPB", "GNG5", "GNPAT", "GNS", "GOLIM4", "GPD2", "GRB2", "GSTA4", "GSTO1", "GUSB", "GYG1", "HACD3", "HADH", "HAUS1", "HAUS3", "HAUS4", "HEBP1", "HLA-A", "HLA-B", "HLA-C", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPF", "HNRNPH1", "HS2ST1", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSPA8", "ICMT", "IDH1", "IDH2", "IFNGR1", "IQGAP1", "IQGAP2", "KDELR1", "KDELR3", "KDM1B", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KLC1", "KLC2", "KLC4", "KPNA2", "LAMC1", "LAMTOR2", "LBR", "LMAN1", "LMAN2", "LMF2", "LNPEP", "LPGAT1", "LSS", "LTA4H", "M6PR", "MAIP1", "MAN1A2", "MAPK1", "MAPK14", "MBOAT7", "MED14", "MED21", "MFAP1", "MFN2", "MGAT1", "MIA2", "MICU2", "MIF", "MMGT1", "MOGS", "MOV10", "MPC2", 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0000000000000000000000000000000000000000..dcb12e66f90bcfea59bf5c44896327f6b891a729 --- /dev/null +++ b/msigdb_wp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_wp/fragment/C342/C342_val_log2fc"} \ No newline at end of file diff --git a/msigdb_wp/result.tsv b/msigdb_wp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..880bbd84c0dad5569113105522ecfd316d0ee073 --- /dev/null +++ b/msigdb_wp/result.tsv @@ -0,0 +1,173 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Cholesterol metabolism with bloch and kandutschrussell pathways 0.7312338229297874 2.9063219289343296 0.0036570498447978 0.8922090898337951 0.3401152501863224 22 Q16850,Q15125,P37268,P48449,Q15392,Q15800,Q9BWD1,Q14739 8 +Target of rapamycin tor signaling 0.7394168719995362 2.3443348281637624 0.0190610510841044 0.9999917144155268 0.4518664905628284 13 P62942 1 +Ferroptosis 0.6269191795487249 2.2911757707473543 0.0219532497091174 0.9999986239140533 0.4602612352808081 22 P09601,P37268 2 +Cholesterol biosynthesis with skeletal dysplasias 0.894430765076953 2.2035110912656632 0.0275587461063464 0.9999999582235258 0.5236161760205826 6 Q16850,Q14739,Q15125,Q15392 4 +Sphingolipid metabolism integrated pathway 0.7860603113718898 2.150209141050815 0.0315386754265523 0.9999999965483448 0.5639857252748177 8 Q16739,Q96G23,Q06136,O95470,O15270 5 +Sphingolipid metabolism overview 0.7860603113718898 2.150209141050815 0.0315386754265523 0.9999999965483448 0.5639857252748177 8 Q16739,Q96G23,Q06136,O95470,O15270 5 +Statin inhibition of cholesterol production 0.8744476814200973 2.1250534974377606 0.0335821492190004 0.9999999990443794 0.5699374432876927 6 P37268 1 +Metapathway biotransformation phase i and ii 0.5883338991658464 2.123090177214079 0.0337462959841396 0.9999999991381484 0.5699374432876927 24 P07099,Q16850,O15217,Q8NCH0,Q86UY6 5 +Type i collagen synthesis in the context of osteogenesis imperfecta 0.7136317049694648 2.1007343890873686 0.0356642887752784 0.9999999997425008 0.573752666165209 12 P13674,Q96AY3,Q32P28,O15460 4 +Head and neck squamous cell carcinoma 0.611365188468521 2.098516525593399 0.0358595416353255 0.9999999997723292 0.573752666165209 19 P62942,P06730 2 +Sphingolipid metabolism in senescence 0.7289953302868106 2.035832922604913 0.0417671352733075 0.9999999999945748 0.646356276366293 10 Q16739,Q96G23,Q06136,P28482,P04062 5 +Sphingolipid pathway 0.7274027565912319 2.028360786120438 0.0425234392346245 0.9999999999966432 0.646356276366293 10 Q16739,Q96G23,Q06136,O95470,O15270,P04062 6 +Folate metabolism 0.6204025208900292 2.0162529022700504 0.043773537090034 0.9999999999984832 0.6491295256278222 17 P00374,P41440,Q8WTV0,P34896 4 +Cholesterol biosynthesis pathway 0.6919152891558163 1.9934729949065455 0.0462096777765714 0.9999999999996784 0.6689400973370346 12 P48449,Q16850,Q15800,P37268 4 +Spinal cord injury 0.5856496698221393 1.9712120811028409 0.0486996226321581 0.9999999999999344 0.6885900130314448 20 P62942,P14174,P04083,P28482 4 +Metabolism of spingolipids in er and golgi apparatus 0.8103551283044879 1.868736326206212 0.0616595074262447 1.0 0.6950330897348515 6 Q16739,Q06136,O95470,P15291 4 +Intracellular trafficking proteins involved in cmt neuropathy 0.6829865885517132 1.8496172602244771 0.0643687333121574 1.0 0.6950330897348515 11 O95140,Q9NR77 2 +Nanomaterial induced apoptosis 0.8261763353701398 1.8142479146966233 0.0696395664269597 1.0 0.6950330897348515 5 O95831,P49327,Q9NR28 3 +Regucalcin in proximal tubule epithelial kidney cells 0.7511006109668696 1.8025803941626284 0.0714541383898668 1.0 0.6950330897348515 7 P31749,P28482 2 +Mecp2 and associated rett syndrome 0.5483237621402418 1.7951825119787763 0.0726246258246052 1.0 0.6950330897348515 22 P31943,Q03518,P31749,Q13451,P67809,P35637 6 +Caloric restriction and aging 0.8213141481652884 1.7947624832232123 0.0726915505646204 1.0 0.6950330897348515 5 P43490 1 +Allograft rejection 0.6747688208344974 1.7777332808749975 0.0754476709251648 1.0 0.6950330897348515 10 P08183,P10321,P04439,P49327,P08670,Q9BY49,P42574 7 +Adipogenesis 0.5935540952335281 1.696264487029942 0.0898358027245489 1.0 0.7715614159087822 14 P14174,P43490,O75844 3 +Mevalonate arm of cholesterol biosynthesis pathway 0.6568271195186146 1.690707964702136 0.0908925923779433 1.0 0.7715614159087822 10 P37268 1 +Nrf2 pathway 0.5363369189916505 1.6880144179392955 0.0914084612935917 1.0 0.7715614159087822 21 O15217 1 +Ethanol effects on histone modifications 0.6420255013391201 1.648338903268157 0.0992831457869625 1.0 0.775912986905648 11 P00374 1 +Cytosine methylation 0.8674392066677463 1.606321369931463 0.1082033173453247 1.0 0.7926218909151499 4 P48735 1 +Photodynamic therapyinduced nfe2l2 nrf2 survival signaling 0.7724382298279312 1.597168464565086 0.1102281601648145 1.0 0.7972547112253048 5 P09601 1 +Sterol regulatory elementbinding proteins srebp signaling 0.4865569587361857 1.5858665690939964 0.1127695808641056 1.0 0.7972547112253048 31 P48449,Q16850,Q8WTV0,P37268 4 +Proteasome degradation 0.4548829283991994 1.5658130286402547 0.1173923952027387 1.0 0.8005445922001395 41 P28070,P25786,P10321,P20618,P28074,P49721,P28072 7 +Hostpathogen interaction of human coronaviruses apoptosis 0.7507710025420747 1.5086860998936873 0.1313790193845085 1.0 0.8005445922001395 5 P31749,P42574 2 +Familial partial lipodystrophy fpld 0.6817778230157513 1.499186697146099 0.1338252051334745 1.0 0.8005445922001395 7 O60725 1 +Vitamin d metabolism 0.9299458809380632 1.4990207443344203 0.1338682505668045 1.0 0.8005445922001395 3 P38435,P04062 2 +Proteoglycan biosynthesis 0.7476574684995339 1.4959336321773085 0.1346709509575789 1.0 0.8005445922001395 5 Q8NCH0 1 +Alzheimers disease 0.4056065870060968 1.488319880655656 0.1366665544440606 1.0 0.8005445922001395 91 P28070,P25786,O95197,P12235,P28074,Q9UJX6,P42574,P60900,P20618,P49721,P28072,P0DP25,O15111,P21796,P45880,P31749,P49327,O14641,P78536,P16615,Q07866,Q00535,P28482 23 +Alzheimers disease and mirna effects 0.4033752265208397 1.4548028175659895 0.1457238579534703 1.0 0.8191276199620023 92 P28070,P25786,O95197,P12235,P28074,Q9UJX6,P42574,P60900,P20618,P49721,P28072,P0DP25,O15111,P21796,P45880,P31749,P49327,O14641,P78536,P16615,Q07866,Q00535,P28482 23 +4hydroxytamoxifen dexamethasone and retinoic acids regulation of p27 expression 0.6136919044675289 1.451565425423881 0.1466224781551282 1.0 0.8191276199620023 9 P31749,P06730 2 +Striated muscle contraction pathway 0.6667342006851589 1.4323521237711476 0.1520430728232034 1.0 0.825248266692557 7 P67936,P08670,P09493 3 +Immune response to tuberculosis 0.8193072888474222 1.4208573861996912 0.1553582236177182 1.0 0.825248266692557 4 O60244,Q03518 2 +Kennedy pathway from sphingolipids 0.8163495155025113 1.409426553678174 0.1587090768850423 1.0 0.825248266692557 4 O95470 1 +Mitochondrial complex iii assembly 0.5996909752909549 1.408661122772351 0.1589353958499089 1.0 0.825248266692557 10 O14949,Q9UDW1 2 +Kallmann syndrome 0.8138338535312506 1.3997024900082562 0.1616024278567231 1.0 0.825248266692557 4 P31749,P28482 2 +Vitamin b12 metabolism 0.5984442235740343 1.3765356379302494 0.1686558617346327 1.0 0.8314895723490826 9 Q8WTV0 1 +Mitochondrial long chain fatty acid betaoxidation 0.5541967312640418 1.3729405139015587 0.1697708403535007 1.0 0.8314895723490826 13 Q16836,P23786,O43772 3 +Ketogenesis and ketolysis 0.6847162994409703 1.3480109270976133 0.1776548681135208 1.0 0.8314895723490826 6 O43772 1 +Electron transport chain oxphos system in mitochondria 0.4077465846883524 1.347604571836285 0.1777855993509551 1.0 0.8314895723490826 55 Q7KZN9,O43676,P20674,O75964,P12235,Q9Y6M9,Q9UDW1,O75306,O75438,O95168,P00846,P14406,O75880,O14949 14 +Oxidation by cytochrome p450 0.6984941190131517 1.2936350974404796 0.1957914933010507 1.0 0.8650023268178098 5 O43169 1 +Serine metabolism 0.6305645263224715 1.2705715563587447 0.2038811112709728 1.0 0.8729557440334612 7 P00374,P34896 2 +Onecarbon metabolism and related pathways 0.5333871154966078 1.257925625627687 0.2084186551338218 1.0 0.8741866663997035 13 P35790,P34896 2 +Vitamin d receptor pathway 0.5237283719679366 1.2042736367508216 0.2284838328183573 1.0 0.8959354761459465 13 P08183,P04080,Q92783,P09493,Q5VV42,Q96KA5 6 +Nephrotic syndrome 0.5345083219140329 1.1783577038055282 0.2386540322197925 1.0 0.8959354761459465 12 Q14108,O75844 2 +Angiogenesis 0.7490143452713203 1.1492229603665578 0.250464055563931 1.0 0.9061102938041627 4 P31749,P28482 2 +3q29 copy number variation syndrome 0.5269827537772447 1.1381091173514744 0.2550749214995336 1.0 0.9061102938041627 12 P31749,O94888 2 +Copper homeostasis 0.5451498059971518 1.1339342184603705 0.2568221422513717 1.0 0.9061102938041627 10 P78536,Q9Y6N1,P31749,P42574,O75880 5 +Alpha 6 beta 4 signaling pathway 0.5240054213208357 1.1221703459511594 0.2617900184581203 1.0 0.9061102938041627 12 P31749,P11047,P28482 3 +Vitamin a and carotenoid metabolism 0.822729777425986 1.1012216286599954 0.2708002105679092 1.0 0.9188255314002868 3 Q8WTV0 1 +Oxysterols derived from cholesterol 0.5597407063933798 1.101212368369971 0.2708042399159112 1.0 0.9188255314002868 8 Q15125 1 +Apoptosis modulation by hsp70 0.6212657657601307 1.0795284859366303 0.2803522021523481 1.0 0.9254190972959734 6 O95831,P49327,P42574 3 +Progeriaassociated lipodystrophy 0.5338783731582969 1.076769815290643 0.2815831134864393 1.0 0.9254190972959734 10 O60725 1 +Male infertility 0.4477433704392359 1.062038522705004 0.2882181972099529 1.0 0.933849919157716 19 P08183,Q15165,P34896,P41440,P49327 5 +7oxoc and 7betahc pathways 0.5256024924304932 1.0347675338674067 0.300777488348241 1.0 0.9495495244908502 10 Q15125,Q9UBM7 2 +Cohesin complex cornelia de lange syndrome 0.4616719939279253 1.0125505107720765 0.311274908591898 1.0 0.9495495244908502 16 P30154 1 +Mitochondrial complex iv assembly 0.4878285315177776 1.003907452181222 0.3154232242360852 1.0 0.9495495244908502 13 P14406,Q7KZN9,Q9Y2R0,P20674 4 +Disruption of postsynaptic signaling by cnv 0.5346063409857165 0.9805806251360089 0.3267995926096294 1.0 0.9552603476281476 8 P28482,Q06787,Q14168 3 +Triacylglyceride synthesis 0.7829224293445554 0.956165896669517 0.338988426655668 1.0 0.9721932236162554 3 O15228,O00116 2 +Regulation of apoptosis by parathyroid hormonerelated protein 0.5572715601448799 0.9409003223002458 0.3467559424501254 1.0 0.982584732357644 7 P31749 1 +Disorders of folate metabolism and transport 0.5260130727599964 0.9394014156220764 0.3475246864763976 1.0 0.982584732357644 8 P00374 1 +Nuclear receptors metapathway 0.3680744141611722 0.935837909683147 0.349356649609257 1.0 0.982584732357644 50 O15217,P23786,P09601,Q15067 4 +Mammary gland development pathway pregnancy and lactation stage 3 of 4 0.5866034595782179 0.9332473965759848 0.3506922482263301 1.0 0.982584732357644 6 O15111,P06730 2 +Phosphodiesterases in neuronal function 0.7379020138262513 0.8878094948234206 0.3746432346869808 1.0 0.9946859680772242 2 O43924 1 +Onecarbon metabolism 0.4448633705579515 0.8730377775704139 0.3826424869442872 1.0 1.0 15 P00374,P34896 2 +Erk pathway in huntingtons disease 0.6727372165063132 0.8591858998297573 0.3902379613094564 1.0 1.0 4 P42858,P28482 2 +Cellular proteostasis 0.5688890101447857 0.8590686166793344 0.390302660579835 1.0 1.0 6 Q9UHV9,O60925 2 +Influence of laminopathies on wnt signaling 0.4742736746578034 0.8556572198298426 0.3921874098008358 1.0 1.0 12 O60725 1 +Embryonic stem cell pluripotency pathways 0.446973965525642 0.8521278356123815 0.394143144045024 1.0 1.0 14 P31749,O14641,P28482 3 +Pyrimidine metabolism 0.3572665308373758 0.8264754455547897 0.4085344413195306 1.0 1.0 46 Q9H773,Q9Y2S7,P17812,Q14181,Q9NR33,Q7LG56,Q9NRF8 7 +Complement system in neuronal development and plasticity 0.4812886096704534 0.8103990183786315 0.4177108818630402 1.0 1.0 10 P49327,P42574,Q5KU26,Q9NR28 4 +Nonalcoholic fatty liver disease 0.3502854105802926 0.7889486578085096 0.4301420150502988 1.0 1.0 56 O43676,P20674,P49327,Q9UDW1,O75306,P31749,O75438,O95168,Q86Y39,P14406,O14949 11 +Translation factors 0.3700076358578699 0.7693795572377105 0.4416680207277359 1.0 1.0 37 P06730,O75153 2 +Neural crest cell migration in cancer 0.4683322420042812 0.7625811048773306 0.4457132567983914 1.0 1.0 11 Q99523 1 +Transsulfuration and onecarbon metabolism 0.4010064005254233 0.7540569940147327 0.4508149995150736 1.0 1.0 19 P00374,P34896 2 +Epo receptor signaling 0.5061290733130924 0.7141394641474429 0.4751409451195871 1.0 1.0 7 P31749,P28482 2 +Fluoropyrimidine activity 0.4470887132679998 0.711147880967642 0.4769926017247674 1.0 1.0 12 P00374,Q92820,P04818,Q06203 4 +Glycerophospholipid biosynthetic pathway 0.5054247055475124 0.7110662596045983 0.4770431770110819 1.0 1.0 7 P48651,O15228,O00116,O95674 4 +Overlap between signal transduction pathways contributing to lmna laminopathies 0.4117306653995913 0.7078975925593176 0.4790088548595315 1.0 1.0 16 O75844,P25054,P11802,P55209,O60725,P50402 6 +Vitamin dsensitive calcium signaling in depression 0.5529716668123603 0.7014240668463433 0.4830384069193001 1.0 1.0 5 Q8NB78 1 +Nucleotide metabolism 0.4152094360737812 0.6969491997313687 0.4858345860891924 1.0 1.0 15 P00374 1 +Camkk2 pathway 0.4272273848680192 0.6671048664120715 0.5047051519228365 1.0 1.0 13 O00429,O76024,P09601,Q9Y3D6,P28482 5 +Tgfbeta signaling in thyroid cells for epithelialmesenchymal transition 0.5438658908300906 0.6660604897323373 0.5053724373602078 1.0 1.0 5 P31749,P28482 2 +Rala downstream regulated genes 0.512177576581176 0.6271872356467508 0.530536509258547 1.0 1.0 6 P16989 1 +Inhibition of exosome biogenesis and secretion by manumycin a in crpc cells 0.4452091827986744 0.6169089523549552 0.5372947815844782 1.0 1.0 9 P31943,P28482,P61020 3 +Riboflavin and coq disorders 0.6052610310305482 0.6157435110481846 0.5380638152129515 1.0 1.0 4 Q8NI60,Q16134 2 +Regulation of sister chromatid separation at the metaphaseanaphase transition 0.4413919797837843 0.6119154175849308 0.5405937204597326 1.0 1.0 10 O60566,Q9UJX6,Q02224 3 +Apoptosis 0.3724682921335049 0.5334642039653327 0.5937122837854929 1.0 1.0 18 Q9NR28,Q13546,Q99590,P31749,P49327,P42574,O15111 7 +Photodynamic therapyinduced ap1 survival signaling 0.4243187579026286 0.5291612766881335 0.5966935765882717 1.0 1.0 10 P49327,Q16539,P42771 3 +Angiopoietinlike protein 8 regulatory pathway 0.3460006347145932 0.5226089928659944 0.6012463811476034 1.0 1.0 33 P46108,P31749,P41440,P06730,P49327 5 +Endometrial cancer 0.3877837980303247 0.5130240558152535 0.607934493524215 1.0 1.0 14 P31749,Q9UJX6,P28482 3 +Hedgehog signaling pathway wp47 0.629696423204092 0.4992789512181371 0.6175828814903452 1.0 1.0 2 O00422 1 +Type ii interferon signaling ifng 0.4288885723816825 0.4873673816667584 0.6259980046222968 1.0 1.0 8 P15260,Q03518 2 +Tnfalpha signaling pathway 0.3480122322198318 0.4805633933799452 0.6308268378710773 1.0 1.0 25 P62993,Q9NR28,Q13546,P31749,P28482,P42574,O15111 7 +Nitric oxide metabolism in cystic fibrosis 0.5645112781954916 0.4799694672134739 0.6312491039891284 1.0 1.0 4 Q99873,Q86X55,O14744 3 +Glycogen synthesis and degradation 0.3579200107808866 0.4759225364543913 0.6341295659577413 1.0 1.0 19 P46976,P30154,P30153,P52789,P0DP25 5 +Primary focal segmental glomerulosclerosis fsgs 0.357150838088476 0.4710799445944228 0.6375836463776574 1.0 1.0 19 P31749,Q14108,P11047 3 +Methylation pathways 0.5600657375627786 0.4658535431897883 0.6413203363567703 1.0 1.0 4 P21964 1 +Complement system 0.4079274616187534 0.4625775084376134 0.6436672333879541 1.0 1.0 11 P26885 1 +Dna mismatch repair 0.3509617580797139 0.4493325177262459 0.6531918035425677 1.0 1.0 21 Q9UQ84,Q9NR33,P41440 3 +Relationship between inflammation cox2 and egfr 0.4848073503227024 0.4482028966732063 0.6540067723843377 1.0 1.0 5 P31749,P28482 2 +Oxidative phosphorylation 0.3358054261857571 0.4431308508577415 0.6576710915709922 1.0 1.0 33 O75964,O75306,O75438,O95168,Q86Y39,P00846 6 +Pyrimidine metabolism and related diseases 0.4079557736181827 0.4418350094550001 0.6586086025927747 1.0 1.0 9 Q9H0P0 1 +Mthfr deficiency 0.4114727870342852 0.4118068370794324 0.6804810096698986 1.0 1.0 8 P35790,P21964 2 +Wntbetacatenin signaling pathway in leukemia 0.4527713707095913 0.401685182657565 0.6879157306964663 1.0 1.0 6 P31749,P25054 2 +Glycosylation and related congenital defects 0.3990305026467373 0.4015061432506581 0.6880475161225439 1.0 1.0 9 Q9Y5P6,O75340,Q13724,P15291 4 +Integrated cancer pathway 0.3573551690626196 0.3881490064618744 0.6979057674067233 1.0 1.0 16 P31749,P42574,P53350,O14757 4 +Dna damage response 0.3346386663721708 0.3879645285228209 0.6980422837725437 1.0 1.0 25 O14757,Q00535,P41440,P49327,Q7LG56 5 +Network map of sarscov2 signaling pathway 0.3314330264951745 0.3873500385443624 0.6984970857772139 1.0 1.0 29 Q99829,Q07021,P31749,P07858,Q9P253,P06730,Q08380,P31350,P42574 9 +Biomarkers for pyrimidine metabolism disorders 0.3954509186141672 0.3855498710029447 0.6998300650447762 1.0 1.0 9 Q9H0P0 1 +Complement and coagulation cascades 0.6031267985612769 0.373880243553198 0.7084934156267857 1.0 1.0 3 P49257 1 +Il6 signaling pathway 0.3787393390933758 0.3638473333454964 0.7159720147157382 1.0 1.0 12 P31749,P28482 2 +Mirna regulation of dna damage response 0.3272522048593235 0.3512992678910064 0.7253638441258274 1.0 1.0 26 O14757,Q00535,P41440,P49327,Q7LG56 5 +Pi3kakt signaling pathway 0.3059716610510352 0.3496145539324817 0.7266279869867984 1.0 1.0 46 P11047,P30154,P31749,P30153,P06730,P28482 6 +Wnt signaling pathway and pluripotency 0.341069868214859 0.3435170859306217 0.731209489270402 1.0 1.0 18 P30154,P30153 2 +Wnt signaling pathway 0.3522284509378043 0.3390033333828709 0.7346072190271928 1.0 1.0 15 P31749,O14641 2 +Factors and pathways affecting insulinlike growth factor igf1akt signaling 0.3712177174496999 0.3281439211781415 0.742802846576228 1.0 1.0 12 P06730 1 +Egfr tyrosine kinase inhibitor resistance 0.3403608514134233 0.3152385124330793 0.7525805664245275 1.0 1.0 17 P31749,P28482,P06730 3 +Mitochondrial complex i assembly model oxphos system 0.3209549479523324 0.3150818374840266 0.7526995182935652 1.0 1.0 30 Q8N183,O43676,Q9Y6M9,Q96CU9,Q9NPL8,O75306,O75438,O95168 8 +Tlr4 signaling and tolerance 0.3871073270099457 0.3111247845596847 0.7557057601752228 1.0 1.0 8 Q15629,O15111 2 +Chromosomal and microsatellite instability in colorectal cancer 0.324235931237308 0.2810336572083039 0.7786845849621149 1.0 1.0 21 P31749,P11233,Q9UJX6,P28482 4 +Nocgmppkg mediated neuroprotection 0.3788656029105065 0.2786585346016582 0.7805068870258911 1.0 1.0 8 P30536 1 +Nonsmall cell lung cancer 0.3369209681189626 0.2758613666439022 0.7826545478648301 1.0 1.0 16 P62993,Q13043,P31749,P42771,P28482,P42574 6 +Dna replication 0.314485380066197 0.2688198750041463 0.7880682980954343 1.0 1.0 30 P41440,Q9Y2S7,Q14181,Q9Y619 4 +Thermogenesis 0.3138260320533856 0.2671841596215007 0.7893273717487541 1.0 1.0 31 O43772 1 +Pancreatic adenocarcinoma pathway 0.3133772935677226 0.2569506992953647 0.7972168317399266 1.0 1.0 27 Q13177,P11233,P31749,P30086,P42771,P28482,O15111 7 +Tnfrelated weak inducer of apoptosis tweak signaling pathway 0.3476996430992594 0.2555040908449593 0.7983337844066973 1.0 1.0 13 Q13546,P31749,P28482,P42574,O15111 5 +Apoptosis modulation and signaling 0.3199817563172215 0.2461530771701465 0.8055637371196465 1.0 1.0 19 Q9NR28,Q13546,O95831,P42771,P49327,P42574 6 +Netrinunc5b signaling pathway 0.3344419847481036 0.2459312036474161 0.8057354884677155 1.0 1.0 15 P30154,P28482,P31749 3 +Bdnftrkb signaling 0.3552835875203157 0.2209562567070841 0.8251264932371432 1.0 1.0 10 P31749,P28482 2 +Reninangiotensinaldosterone system raas 0.5376766795661361 0.2208733901321831 0.8251910173341153 1.0 1.0 3 P0DP25 1 +Mrna protein and metabolite inducation pathway by cyclosporin a 0.5166816952209259 0.2064183282553058 0.8364641552268575 1.0 1.0 2 Q15758 1 +Bile acids synthesis and enterohepatic circulation 0.4617049604984938 0.201540716741364 0.8402757951810136 1.0 1.0 4 P51114 1 +Endothelin pathways 0.3581495524464032 0.2012589903369698 0.840496067390309 1.0 1.0 8 P28482,P42892 2 +Robo4 and vegf signaling pathways crosstalk 0.5124737000300569 0.1985941866662957 0.842580201404939 1.0 1.0 2 P63000 1 +Envelope proteins and their potential roles in edmd physiopathology 0.3124890799227736 0.1830447566199269 0.8547629011231681 1.0 1.0 18 P28482,Q14739,P62993,P50402 4 +Melanoma 0.3212763221909093 0.1805905751088914 0.8566889542207101 1.0 1.0 15 P62993,P31749,P42771,P28482,P0DP25 5 +Familial hyperlipidemia type 4 0.4507687860703409 0.1789242857377857 0.8579971532300972 1.0 1.0 4 P49327 1 +Il7 signaling pathway 0.3674537059751015 0.1776621021834848 0.8589883497618325 1.0 1.0 7 P31749 1 +Neovascularisation processes 0.4418868713407178 0.1616796405950744 0.8715581380333548 1.0 1.0 4 P31749 1 +Integrinmediated cell adhesion 0.3003803946382917 0.1499575372584992 0.8807981167139085 1.0 1.0 23 P46108,P31749,P28482 3 +Il18 signaling pathway 0.2822313118024266 0.1358518060746926 0.8919384353318955 1.0 1.0 62 Q8TCT8,Q16836,Q9UMR5,Q92733,P09601,P49327,Q9HC07,P35613 8 +Regulation of wnt bcatenin signaling by small molecule compounds 0.3641323846469898 0.1305826682642349 0.8961054540347688 1.0 1.0 6 P25054,O14641 2 +Synaptic signaling pathways associated with autism spectrum disorder 0.3177818829708944 0.1225369745133797 0.9024737651900174 1.0 1.0 13 P31749 1 +Il9 signaling pathway 0.360273348817748 0.1212623023448678 0.9034832779943738 1.0 1.0 6 P28482 1 +Monoamine transport 0.4132330827067711 0.1130219290844476 0.910013169711056 1.0 1.0 4 O15127,Q16539,P49815 3 +Kisspeptinkisspeptin receptor system in the ovary 0.3432216366657066 0.1077717043041349 0.914176788824418 1.0 1.0 7 P31749 1 +Follicle stimulating hormone fsh signaling pathway 0.324050563566161 0.1036071513167117 0.9174811122802342 1.0 1.0 10 P31749 1 +Eicosanoid synthesis 0.4535801395577375 0.0935142995052407 0.9254949901119168 1.0 1.0 3 P09960 1 +Interferon type i signaling pathways 0.2975963670408904 0.0925068687423703 0.9262953341563772 1.0 1.0 17 P06730 1 +Degradation pathway of sphingolipids including diseases 0.3466781000099491 0.0903410357073783 0.9280162116735592 1.0 1.0 6 P17900 1 +Tcell receptor tcr signaling pathway 0.2900278593752758 0.0874042298953151 0.9303502072781182 1.0 1.0 22 P46108,P28482,P31749,P49327,P08670 5 +Hepatitis c and hepatocellular carcinoma 0.3084121901854996 0.0846901322348677 0.9325077411182434 1.0 1.0 13 P31749,P62993,P42574,Q16539 4 +Mapk cascade 0.3342447959150786 0.0844675353707097 0.9326847135923828 1.0 1.0 7 P28482 1 +Sulfation biotransformation reaction 0.4107035478051771 0.0576987224443129 0.9539886113443934 1.0 1.0 3 P11413,O43252 2 +Preimplantation embryo 0.310635572419527 0.051444837679219 0.9589710567512428 1.0 1.0 8 Q99729 1 +Hepatocyte growth factor receptor signaling 0.3027086761173562 0.0451176358716277 0.9640135443433464 1.0 1.0 12 P46108,P28482 2 +Praderwilli and angelman syndrome 0.3108444495968208 0.0307242426499725 0.9754894574478088 1.0 1.0 7 Q7L576,P42771 2 +Ras and bradykinin pathways in covid19 0.3102243325113497 0.0277896650292849 0.977829908892655 1.0 1.0 5 P28482 1 +Nucleotide excision repair 0.2763917211680479 0.0229941939706381 0.9816549042664158 1.0 1.0 25 Q9NR33,P54725,P41440 3 +Tp53 network 0.2681900180396947 0.0227470680682857 0.9818520306462032 1.0 1.0 3 Q07812,P42771 2 +Familial hyperlipidemia type 5 0.254359591100428 0.0223755096401719 0.982148415936329 1.0 1.0 3 Q9UBV2,Q07954 2 +Familial hyperlipidemia type 1 0.254359591100428 0.0223755096401719 0.982148415936329 1.0 1.0 3 Q9UBV2,Q07954 2 +Nanoparticlemediated activation of receptor signaling 0.3064855085990501 0.0218585902083155 0.9825607571020564 1.0 1.0 7 P28482 1 +Interleukin1 il1 structural pathway 0.2916935810889428 0.0088240514797542 0.9929595169272531 1.0 1.0 12 P28482,O15111,P06730 3 +Bladder cancer 0.2989541775108546 0.0060999289821753 0.9951329910260116 1.0 1.0 6 P28482,P42771 2 diff --git a/msigdb_wp/selections.json b/msigdb_wp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..6cab58150d1f9ee45a87c306d2a3728c76a9423e --- /dev/null +++ b/msigdb_wp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["15q112 copy number variation syndrome", "15q133 copy number variation syndrome", "16p112 distal deletion syndrome", "16p112 proximal deletion syndrome", "1q211 copy number variation syndrome", "22q112 copy number variation syndrome", "3q29 copy number variation syndrome", "4hydroxytamoxifen dexamethasone and retinoic acids regulation of p27 expression", "7oxoc and 7betahc pathways", "7q1123 copy number variation syndrome", "Ace inhibitor pathway", "Acetylcholine synthesis", "Acquired partial lipodystrophy barraquersimons syndrome", "Activation of nlrp3 inflammasome by sarscov2", "Acute viral myocarditis", "Adipogenesis", "Aerobic glycolysis", "Aflatoxin b1 metabolism", "Agerage pathway", "Airway smooth muscle cell contraction", "Alanine and aspartate metabolism", "Allograft rejection", "Alpha 6 beta 4 signaling pathway", "Altered glycosylation of muc1 in tumor microenvironment", "Alternative pathway of fetal androgen synthesis", "Alzheimers disease", "Alzheimers disease and mirna effects", "Amino acid metabolism", "Amino acid metabolism pathway excerpt histidine catabolism extension", "Ampactivated protein kinase ampk signaling", "Amyotrophic lateral sclerosis als", "Androgen receptor signaling pathway", "Angiogenesis", "Angiopoietinlike protein 8 regulatory pathway", "Angiotensin ii receptor type 1 pathway", "Antiviral and antiinflammatory effects of nrf2 on sarscov2 pathway", "Apoptosis", "Apoptosis modulation and signaling", "Apoptosis modulation by hsp70", "Apoptosisrelated network due to altered notch3 in ovarian cancer", "Arachidonate epoxygenase epoxide hydrolase", "Arrhythmogenic right ventricular cardiomyopathy", "Aryl hydrocarbon receptor pathway wp2586", "Aryl hydrocarbon receptor pathway wp2873", "Arylamine metabolism", "Aspirin and mirnas", "Atm signaling in development and disease", "Atm signaling pathway", "Atr signaling", "Autophagy", "Autosomal recessive osteopetrosis pathways", "B cell receptor signaling pathway", "Base excision repair", "Bdnftrkb signaling", "Benzene metabolism", "Benzoapyrene metabolism", "Bile acids synthesis and enterohepatic circulation", "Biogenic amine synthesis", "Biomarkers for pyrimidine metabolism disorders", "Biomarkers for urea cycle disorders", "Biotin metabolism including iems", "Bladder cancer", "Bmp signaling in eyelid development", "Bmp2wnt4foxo1 pathway in primary endometrial stromal cell differentiation", "Brainderived neurotrophic factor bdnf signaling pathway", "Breast cancer pathway", "Burn wound healing", "Calcium regulation in cardiac cells", "Caloric restriction and aging", "Camkk2 pathway", "Cancer immunotherapy by ctla4 blockade", "Cancer immunotherapy by pd1 blockade", "Cannabinoid receptor signaling", "Canonical and noncanonical notch signaling", "Canonical and noncanonical tgfb signaling", "Canonical nfkb pathway", "Cardiac hypertrophic response", "Cardiac progenitor differentiation", "Ccl18 signaling pathway", "Cell cycle", "Cell differentiation expanded index", "Cell differentiation index", "Cell migration and invasion through p75ntr", "Cells and molecules involved in local acute inflammatory response", "Celltype dependent selectivity of cck2r signaling", "Cellular proteostasis", "Cerebral organic acidurias including diseases", "Chemokine signaling pathway", "Cholesterol biosynthesis pathway", "Cholesterol biosynthesis with skeletal dysplasias", "Cholesterol metabolism with bloch and kandutschrussell pathways", "Chromosomal and microsatellite instability in colorectal cancer", "Ciliary landscape", "Ciliopathies", "Circadian rhythm genes", "Classical pathway of steroidogenesis with glucocorticoid and mineralocorticoid metabolism", "Clear cell renal cell carcinoma pathways", "Codeine and morphine metabolism", "Cohesin complex cornelia de lange syndrome", "Common pathways underlying drug addiction", "Complement and coagulation cascades", "Complement system", "Complement system in neuronal development and plasticity", "Congenital generalized lipodystrophy cgl", "Constitutive androstane receptor pathway", "Control of immune tolerance by vasoactive intestinal peptide", "Copper homeostasis", "Cori cycle", "Corticotropinreleasing hormone signaling pathway", "Cysteine and methionine catabolism", "Cytoplasmic ribosomal proteins", "Cytosine methylation", "Cytosolic dnasensing pathway", "Ddx1 as a regulatory component of the drosha microprocessor", "Degradation pathway of sphingolipids including diseases", "Deregulation of rab and rab effector genes in bladder cancer", "Development of pulmonary dendritic cells and macrophage subsets", "Development of ureteric collection system", "Disorders of folate metabolism and transport", "Disruption of postsynaptic signaling by cnv", "Dna damage response", "Dna damage response only atm dependent", "Dna irdamage and cellular response via atr", "Dna irdouble strand breaks and cellular response via atm", "Dna mismatch repair", "Dna repair pathways full network", "Dna replication", "Dopamine metabolism", "Dopaminergic neurogenesis", "Drug induction of bile acid pathway", "Dual hijack model of vif in hiv infection", "Ebola virus infection in host", "Ebsteinbarr virus lmp1 signaling", "Ectoderm differentiation", "Effect of progerin on genes involved in hutchinsongilford progeria syndrome", "Egfegfr signaling pathway", "Egfr tyrosine kinase inhibitor resistance", "Eicosanoid metabolism via cyclooxygenases cox", "Eicosanoid metabolism via cytochrome p450 monooxygenases pathway", "Eicosanoid metabolism via lipooxygenases lox", "Eicosanoid synthesis", "Electron transport chain oxphos system in mitochondria", "Embryonic stem cell pluripotency pathways", "Endochondral ossification", "Endochondral ossification with skeletal dysplasias", "Endoderm differentiation", "Endometrial cancer", "Endoplasmic reticulum stress response in coronavirus infection", "Endothelin pathways", "Energy metabolism", "Envelope proteins and their potential roles in edmd physiopathology", "Epithelial to mesenchymal transition in colorectal cancer", "Epo receptor signaling", "Erbb signaling pathway", "Erk pathway in huntingtons disease", "Estrogen metabolism", "Estrogen receptor pathway", "Estrogen signaling pathway", "Ethanol effects on histone modifications", "Ethanol metabolism production of ros by cyp2e1", "Eukaryotic transcription initiation", "Exerciseinduced circadian regulation", "Exrna mechanism of action and biogenesis", "Extracellular vesiclemediated signaling in recipient cells", "Extracellular vesicles in the crosstalk of cardiac cells", "Factors and pathways affecting insulinlike growth factor igf1akt signaling", "Familial hyperlipidemia type 1", "Familial hyperlipidemia type 2", "Familial hyperlipidemia type 3", "Familial hyperlipidemia type 4", "Familial hyperlipidemia type 5", "Familial partial lipodystrophy fpld", "Farnesoid x receptor pathway", "Fas ligand pathway and stress induction of heat shock proteins", "Fatty acid betaoxidation", "Fatty acid biosynthesis", "Fatty acid omegaoxidation", "Fatty acid transporters", "Fbxl10 enhancement of maperk signaling in diffuse large bcell lymphoma", "Ferroptosis", "Fgf23 signaling in hypophosphatemic rickets and related disorders", "Fgfr3 signaling in chondrocyte proliferation and terminal differentiation", "Fibrin complement receptor 3 signaling pathway", "Fluoroacetic acid toxicity", "Fluoropyrimidine activity", "Focal adhesion", "Focal adhesion pi3kaktmtorsignaling pathway", "Folate metabolism", "Folatealcohol and cancer pathway hypotheses", "Follicle stimulating hormone fsh signaling pathway", "Foxa2 pathway", "Foxp3 in covid19", "Fragile x syndrome", "Fto obesity variant mechanism", "G protein signaling pathways", "G1 to s cell cycle control", "G13 signaling pathway", "Gaba metabolism aka ghb", "Gaba receptor signaling", "Galanin receptor pathway", "Gammaglutamyl cycle for the biosynthesis and degradation of glutathione including diseases", "Gastric cancer network 1", "Gastric cancer network 2", "Gastrin signaling pathway", "Gdnfret signaling axis", "Genes controlling nephrogenesis", "Genes related to primary cilium development based on crispr", "Genes targeted by mirnas in adipocytes", "Glial cell differentiation", "Glioblastoma signaling pathways", "Glucocorticoid receptor pathway", "Glucuronidation", "Glutathione metabolism", "Glycerolipids and glycerophospholipids", "Glycerophospholipid biosynthetic pathway", "Glycogen synthesis and degradation", "Glycolysis and gluconeogenesis", "Glycolysis in senescence", "Glycosaminoglycan degradation", "Glycosylation and related congenital defects", "Gpcrs class a rhodopsinlike", "Gpr143 in melanocytes and retinal pigment epithelium cells", "Gpr40 pathway", "H19 action rbe2f1 signaling and cdkbetacatenin activity", "Hair follicle development cytodifferentiation part 3 of 3", "Hair follicle development organogenesis part 2 of 3", "Head and neck squamous cell carcinoma", "Heart development", "Hedgehog signaling pathway wp4249", "Hedgehog signaling pathway wp47", "Hematopoietic stem cell gene regulation by gabp alphabeta complex", "Heme biosynthesis", "Hepatitis b infection", "Hepatitis c and hepatocellular carcinoma", "Hepatocyte growth factor receptor signaling", "Hereditary leiomyomatosis and renal cell carcinoma pathway", "Hif1a and pparg regulation of glycolysis", "Hijack of ubiquitination by sarscov2", "Hippo signaling regulation pathways", "Hippomerlin signaling dysregulation", "Hippoyap signaling pathway", "Histone modifications", "Homologous recombination", "Hostpathogen interaction of human coronaviruses apoptosis", "Hostpathogen interaction of human coronaviruses autophagy", "Hostpathogen interaction of human coronaviruses interferon induction", "Hostpathogen interaction of human coronaviruses mapk signaling", "Hypertrophy model", "Hypothesized pathways in pathogenesis of cardiovascular disease", "Hypothetical craniofacial development pathway", "Il1 and megakaryocytes in obesity", "Il1 signaling pathway", "Il10 antiinflammatory signaling pathway", "Il17 signaling pathway", "Il18 signaling pathway", "Il2 signaling pathway", "Il3 signaling pathway", "Il4 signaling pathway", "Il5 signaling pathway", "Il6 signaling pathway", "Il7 signaling pathway", "Il9 signaling pathway", "Imatinib and chronic myeloid leukemia", "Immune response to tuberculosis", "Inclusion body myositis", "Inflammatory response pathway", "Influence of laminopathies on wnt signaling", "Inhibition of exosome biogenesis and secretion by manumycin a in crpc cells", "Initiation of transcription and translation elongation at the hiv1 ltr", "Insulin signaling", "Insulin signaling in adipocytes diabetic condition", "Insulin signaling in adipocytes normal condition", "Integrated cancer pathway", "Integrinmediated cell adhesion", "Interactions between immune cells and micrornas in tumor microenvironment", "Interactions between loxl4 and oxidative stress pathway", "Interactions of natural killer cells in pancreatic cancer", "Interactome of polycomb repressive complex 2 prc2", "Interferon type i signaling pathways", "Interleukin1 il1 structural pathway", "Interleukin1 induced activation of nfkb", "Interleukin11 signaling pathway", "Intracellular trafficking proteins involved in cmt neuropathy", "Intraflagellar transport proteins binding to dynein", "Irinotecan pathway", "Iron metabolism in placenta", "Joubert syndrome", "Kallmann syndrome", "Kennedy pathway from sphingolipids", "Ketogenesis and ketolysis", "Ketone bodies synthesis and degradation", "Kininkallikrein pathway", "Kisspeptinkisspeptin receptor system in the ovary", "Kit receptor signaling pathway", "Krebs cycle disorders", "Kynurenine pathway and links to cell senescence", "Leptin and adiponectin", "Leptin signaling pathway", "Leptininsulin signaling overlap", "Leukocyteintrinsic hippo pathway functions", "Lipid metabolism pathway", "Lipid particles composition", "Liver x receptor pathway", "Lncrna in canonical wnt signaling and colorectal cancer", "Lncrnamediated mechanisms of therapeutic resistance", "Ltf danger signal response pathway", "Lung fibrosis", "Male infertility", "Malignant pleural mesothelioma", "Mammalian disorder of sexual development", "Mammary gland development pathway embryonic development stage 1 of 4", "Mammary gland development pathway involution stage 4 of 4", "Mammary gland development pathway pregnancy and lactation stage 3 of 4", "Mammary gland development pathway puberty stage 2 of 4", "Map3k1 role in promoting and blocking gonadal determination", "Mapk and nfkb signaling pathways inhibited by yersinia yopj", "Mapk cascade", "Mapk pathway in congenital thyroid cancer", "Mapk signaling pathway", "Matrix metalloproteinases", "Mbdnf and probdnf regulation of gaba neurotransmission", "Measles virus infection", "Mechanoregulation and pathology of yaptaz via hippo and nonhippo mechanisms", "Mecp2 and associated rett syndrome", "Melanoma", "Melatonin metabolism and effects", "Mesodermal commitment pathway", "Met in type 1 papillary renal cell carcinoma", "Metabolic pathway of ldl hdl and tg including diseases", "Metabolic reprogramming in colon cancer", "Metabolism of spingolipids in er and golgi apparatus", "Metapathway biotransformation phase i and ii", "Metastatic brain tumor", "Methionine de novo and salvage pathway", "Methionine metabolism leading to sulfur amino acids and related disorders", "Methylation pathways", "Mevalonate arm of cholesterol biosynthesis pathway", "Mevalonate pathway", "Mfap5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement", "Mfap5mediated ovarian cancer cell motility and invasiveness", "Microglia pathogen phagocytosis pathway", "Microrna network associated with chronic lymphocytic leukemia", "Micrornas in cardiomyocyte hypertrophy", "Microtubule cytoskeleton regulation", "Mir124 predicted interactions with cell cycle and differentiation", "Mir5093p alteration of yap1ecm axis", "Mir517 relationship with arcn1 and usp1", "Mirna biogenesis", "Mirna regulation of dna damage response", "Mirna regulation of p53 pathway in prostate cancer", "Mirna regulation of prostate cancer signaling pathways", "Mirna targets in ecm and membrane receptors", "Mirnas involved in dna damage response", "Mirnas involvement in the immune response in sepsis", "Mitochondrial complex i assembly model oxphos system", "Mitochondrial complex ii assembly", "Mitochondrial complex iii assembly", "Mitochondrial complex iv assembly", "Mitochondrial fatty acid synthesis pathway", "Mitochondrial gene expression", "Mitochondrial immune response to sarscov2", "Mitochondrial long chain fatty acid betaoxidation", "Modulators of tcr signaling and t cell activation", "Molybdenum cofactor moco biosynthesis", "Monoamine transport", "Mrna processing", "Mrna protein and metabolite inducation pathway by cyclosporin a", "Mthfr deficiency", "Myd88 distinct inputoutput pathway", "Myometrial relaxation and contraction pathways", "Nad biosynthetic pathways", "Nad metabolism", "Nad metabolism in oncogeneinduced senescence and mitochondrial dysfunctionassociated senescence", "Nad metabolism sirtuins and aging", "Nanomaterial induced apoptosis", "Nanomaterialinduced inflammasome activation", "Nanoparticle triggered autophagic cell death", "Nanoparticle triggered regulated necrosis", "Nanoparticlemediated activation of receptor signaling", "Ncrnas involved in stat3 signaling in hepatocellular carcinoma", "Ncrnas involved in wnt signaling in hepatocellular carcinoma", "Neovascularisation processes", "Nephrogenesis", "Nephrotic syndrome", "Netrinunc5b signaling pathway", "Network map of sarscov2 signaling pathway", "Neural crest cell migration during development", "Neural crest cell migration in cancer", "Neural crest differentiation", "Neurodegeneration with brain iron accumulation nbia subtypes pathway", "Neuroinflammation", "Neuroinflammation and glutamatergic signaling", "Nicotine effect on dopaminergic neurons", "Nipbl role in dna damage cornelia de lange syndrome", "Nitric oxide metabolism in cystic fibrosis", "Nocgmppkg mediated neuroprotection", "Nodlike receptor nlr signaling pathway", "Nonalcoholic fatty liver disease", "Nongenomic actions of 125 dihydroxyvitamin d3", "Nonhomologous end joining", "Nonsmall cell lung cancer", "Notch signaling", "Notch signaling pathway", "Notch1 regulation of endothelial cell calcification", "Novel intracellular components of rigilike receptor rlr pathway", "Nrf2 pathway", "Nrf2are regulation", "Nrp1triggered signaling pathways in pancreatic cancer", "Nsp1 from sarscov2 inhibits translation initiation in the host cell", "Nuclear receptors in lipid metabolism and toxicity", "Nuclear receptors metapathway", "Nucleotide excision repair", "Nucleotide excision repair in xeroderma pigmentosum", "Nucleotide metabolism", "Nucleotidebinding oligomerization domain nod pathway", "Oligodendrocyte specification and differentiation leading to myelin components for cns", "Omega3 omega6 fatty acid synthesis", "Omega9 fatty acid synthesis", "Oncostatin m signaling pathway", "Onecarbon metabolism", "Onecarbon metabolism and related pathways", "Orexin receptor pathway", "Osteoblast differentiation and related diseases", "Osteoclast signaling", "Osteopontin signaling", "Osx and mirnas in tooth development", "Ovarian infertility", "Overlap between signal transduction pathways contributing to lmna laminopathies", "Overview of interferonsmediated signaling pathway", "Overview of nanoparticle effects", "Overview of proinflammatory and profibrotic mediators", "Oxidation by cytochrome p450", "Oxidative damage response", "Oxidative phosphorylation", "Oxidative stress response", "Oxysterols derived from cholesterol", "P38 mapk signaling pathway", "P53 transcriptional gene network", "Pancreatic adenocarcinoma pathway", "Parkinsons disease pathway", "Parkinubiquitin proteasomal system pathway", "Pathogenesis of sarscov2 mediated by nsp9nsp10 complex", "Pathogenic escherichia coli infection", "Pathways affected in adenoid cystic carcinoma", "Pathways of nucleic acid metabolism and innate immune sensing", "Pdgf pathway", "Pdgfrbeta pathway", "Pentose phosphate metabolism", "Pentose phosphate pathway in senescent cells", "Peroxiredoxin 2 induced ovarian failure", "Phase i biotransformations non p450", "Phosphodiesterases in neuronal function", "Phosphoinositides metabolism", "Photodynamic therapyinduced ap1 survival signaling", "Photodynamic therapyinduced hif1 survival signaling", "Photodynamic therapyinduced nfe2l2 nrf2 survival signaling", "Photodynamic therapyinduced nfkb survival signaling", "Photodynamic therapyinduced unfolded protein response", "Physicochemical features and toxicityassociated pathways", "Physiological and pathological hypertrophy of the heart", "Pi3kakt signaling pathway", "Pi3kaktmtor signaling pathway and therapeutic opportunities", "Pi3kaktmtor vitd3 signaling", "Pilocytic astrocytoma", "Pkcgamma calcium signaling pathway in ataxia", "Ppar signaling pathway", "Pparalpha pathway", "Praderwilli and angelman syndrome", "Pregnane x receptor pathway", "Preimplantation embryo", "Primary focal segmental glomerulosclerosis fsgs", "Prion disease pathway", "Progeriaassociated lipodystrophy", "Prolactin signaling pathway", "Prostaglandin and leukotriene metabolism in senescence", "Prostaglandin signaling", "Prostaglandin synthesis and regulation", "Proteasome degradation", "Proteoglycan biosynthesis", "Proximal tubule transport", "Ptf1a related regulatory pathway", "Purine metabolism", "Purine metabolism and related disorders", "Purinergic signaling", "Pyrimidine metabolism", "Pyrimidine metabolism and related diseases", "Quercetin and nfkb ap1 induced apoptosis", "Rac1pak1p38mmp2 pathway", "Rala downstream regulated genes", "Ranklrank signaling pathway", "Ras and bradykinin pathways in covid19", "Ras signaling", "Regucalcin in proximal tubule epithelial kidney cells", "Regulation of actin cytoskeleton", "Regulation of apoptosis by parathyroid hormonerelated protein", "Regulation of sister chromatid separation at the metaphaseanaphase transition", "Regulation of wnt bcatenin signaling by small molecule compounds", "Regulatory circuits of the stat3 signaling pathway", "Relationship between inflammation cox2 and egfr", "Reninangiotensinaldosterone system raas", "Resistin as a regulator of inflammation", "Retinoblastoma gene in cancer", "Rett syndrome causing genes", "Riboflavin and coq disorders", "Robo4 and vegf signaling pathways crosstalk", "S1p receptor signal transduction", "Sars coronavirus and innate immunity", "Sarscov2 and covid19 pathway", "Sarscov2 b117 variant antagonises innate immune activation", "Sarscov2 innate immunity evasion and cellspecific immune response", "Sarscov2 replication organelle formation", "Selective expression of chemokine receptors during tcell polarization", "Selenium micronutrient network", "Serine metabolism", "Serotonin and anxiety", "Serotonin and anxietyrelated events", "Serotonin htr1 group and fos pathway", "Serotonin receptor 2 and elksrfgata4 signaling", "Serotonin receptor 467 and nr3c signaling", "Serotonin transporter activity", "Signal transduction through il1r", "Sleep regulation", "Small cell lung cancer", "Smc1smc3 role in dna damage cornelia de lange syndrome", "Somatroph axis gh and its relationship to dietary restriction and aging", "Sphingolipid metabolism in senescence", "Sphingolipid metabolism integrated pathway", "Sphingolipid metabolism overview", "Sphingolipid pathway", "Spinal cord injury", "Splicing factor nova regulated synaptic proteins", "Srebf and mir33 in cholesterol and lipid homeostasis", "Statin inhibition of cholesterol production", "Steroid biosynthesis", "Sterol regulatory elementbinding proteins srebp signaling", "Sting pathway in kawasakilike disease and covid19", "Striated muscle contraction pathway", "Sudden infant death syndrome sids susceptibility pathways", "Sulfation biotransformation reaction", "Supression of hmgb1 mediated inflammation by thbd", "Synaptic signaling pathways associated with autism spectrum disorder", "Synaptic vesicle pathway", "T cell receptor and costimulatory signaling", "Target of rapamycin tor signaling", "Tca cycle aka krebs or citric acid cycle", "Tca cycle and deficiency of pyruvate dehydrogenase complex pdhc", "Tca cycle in senescence", "Tca cycle nutrient use and invasiveness of ovarian cancer", "Tcell activation sarscov2", "Tcell antigen receptor tcr pathway during staphylococcus aureus infection", "Tcell receptor tcr signaling pathway", "Tgfbeta receptor signaling", "Tgfbeta receptor signaling in skeletal dysplasias", "Tgfbeta signaling in thyroid cells for epithelialmesenchymal transition", "Tgfbeta signaling pathway", "Thermogenesis", "Thiamine metabolic pathways", "Thymic stromal lymphopoietin tslp signaling pathway", "Thyroid hormones production and peripheral downstream signaling effects", "Thyroid stimulating hormone tsh signaling pathway", "Tlr4 signaling and tolerance", "Tnfalpha signaling pathway", "Tnfrelated weak inducer of apoptosis tweak signaling pathway", "Tolllike receptor signaling pathway", "Tolllike receptor signaling related to myd88", "Tp53 network", "Transcription cofactors ski and skil protein partners", "Transcription factor regulation in adipogenesis", "Transcription factors regulate mirnas related to cardiac hypertrophy", "Transcriptional activation by nrf2 in response to phytochemicals", "Translation factors", "Translation inhibitors in chronically activated pdgfra cells", "Transsulfuration and onecarbon metabolism", "Transsulfuration pathway", "Triacylglyceride synthesis", "Tryptophan catabolism leading to nad production", "Tryptophan metabolism", "Tumor suppressor activity of smarcb1", "Type 2 papillary renal cell carcinoma", "Type i collagen synthesis in the context of osteogenesis imperfecta", "Type i interferon induction and signaling during sarscov2 infection", "Type ii diabetes mellitus", "Type ii interferon signaling ifng", "Type iii interferon signaling", "Tyrobp causal network in microglia", "Ultraconserved region 339 modulation of tumor suppressor micrornas in cancer", "Unfolded protein response", "Urea cycle and associated pathways", "Urea cycle and metabolism of amino groups", "Urea cycle and related diseases", "Valproic acid pathway", "Vasopressinregulated water reabsorption", "Vegfavegfr2 signaling pathway", "Vitamin a and carotenoid metabolism", "Vitamin b12 disorders", "Vitamin b12 metabolism", "Vitamin b6dependent and responsive disorders", "Vitamin d in inflammatory diseases", "Vitamin d metabolism", "Vitamin d receptor pathway", "Vitamin dsensitive calcium signaling in depression", "White fat cell differentiation", "Wnt signaling", "Wnt signaling in kidney disease", "Wnt signaling pathway", "Wnt signaling pathway and pluripotency", "Wntbetacatenin signaling pathway in leukemia", "Zinc homeostasis"], "available_proteins": ["AAMP", "AAR2", "AARS", "AASS", "ABCB1", "ABCC4", "ABCD3", "ABCF1", "ABCF2", "ABHD11", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACP1", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR2", "ACTR3", "ADA", "ADAM17", "ADAR", "ADH5", "ADI1", "ADK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGL", "AGPS", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP8", "AKAP9", "AKR1A1", "AKR1B1", "AKT1", "AKT1S1", "ALDH18A1", "ALDH1A2", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG13", "AMOT", "ANAPC1", "ANAPC2", "ANAPC5", "ANAPC7", "ANK3", "ANLN", "ANXA1", "ANXA2", "ANXA4", "ANXA6", "AP1G1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "APC", "APEX1", "APMAP", "APPL1", "APRT", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFGAP3", "ARFIP2", "ARHGAP35", "ARHGAP5", "ARHGDIA", "ARHGEF2", "ARID1A", "ARIH2", "ARL2", "ARL3", "ARL6", "ARL8B", "ARMC9", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARVCF", "ASAH1", "ASCC1", "ASCC3", "ASNA1", "ASNS", "ATAD2", "ATG3", "ATG9A", "ATIC", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V1A", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATRX", "ATXN10", "ATXN2", "ATXN2L", "B3GALT6", "B4GALT1", "BAG2", "BAG3", "BAG4", "BAIAP2", "BANF1", "BAX", "BAZ1A", "BAZ1B", "BCAT2", "BCL2L12", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BLM", "BLVRA", "BLVRB", "BPTF", "BRAP", "BRCA1", "BRD4", "BRIX1", "BSG", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "C15orf39", "C1QBP", "C21orf59", "CAB39", "CACYBP", "CAD", "CADM1", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAP1", "CAP2", "CAPN1", "CAPN2", "CAPNS1", "CAPZB", "CARM1", "CASK", "CASP2", "CASP3", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CCAR2", "CCDC124", "CCDC6", "CCDC88A", "CCNA2", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD47", "CDC23", "CDC25C", "CDC27", "CDC37", "CDC42", "CDC42BPB", "CDC45", "CDC73", "CDCA7L", "CDH2", "CDIPT", "CDK1", "CDK4", "CDK5", "CDK6", "CDKAL1", "CDKN2A", "CDS2", "CDX2", "CEBPZ", "CECR2", "CELF1", "CENPB", "CENPE", "CEP170", "CEP250", "CEP44", "CERS2", "CETN2", "CFL1", "CFL2", "CHAF1A", "CHAMP1", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK1", "CHEK2", "CHKA", "CHMP5", "CHORDC1", "CHP1", "CHRAC1", "CHST14", "CHTF18", "CHTF8", "CHUK", "CIP2A", "CKB", "CLASP1", "CLASP2", "CLIC1", "CLPTM1L", "CLSPN", "CLTA", "CLTC", "CLU", "CLUH", "CMPK1", "CNN2", "CNOT1", "CNOT9", "CNP", "COA3", "COASY", "COLEC12", "COLGALT1", "COMMD1", "COMT", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COQ8A", "COX11", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPNE1", "CPOX", "CPSF1", "CPSF3", "CPT1A", "CPT2", "CRK", "CRKL", "CRTAP", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTH", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYB5B", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DARS", "DAXX", "DBNL", "DCAF1", "DCAF7", "DCP1A", "DCTD", "DCTN1", "DCTN2", "DCTN4", "DCTPP1", "DDB1", "DDOST", "DDX1", "DDX17", "DDX20", "DDX21", "DDX3X", "DDX5", "DDX52", "DDX56", "DEK", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHODH", "DHX15", "DHX16", "DHX29", "DHX36", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DLAT", "DLD", "DLST", "DNAAF5", "DNAJA1", "DNAJB1", "DNAJB11", "DNAJC3", "DNAJC7", "DNAJC8", "DNM1L", "DNM2", "DNMT1", "DPF2", "DPM1", "DPP9", "DPYSL2", "DSC3", "DSG2", "DSP", "DSTN", "DTYMK", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EBP", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECSIT", "ECT2", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFTUD2", "EGFR", "EGLN1", "EHBP1", "EHD1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2AK4", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF4A1", "EIF4A2", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAVL1", "ELL", "ELOA", "ELOB", "ELOC", "ELP4", "EMD", "EML4", "ENAH", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L5", "EPHX1", "EPHX2", "EPN1", "EPRS", "EPS15", "EPS15L1", "ERBIN", "ERCC2", "ERCC3", "ERI1", "ESD", "ESS2", "ETF1", "ETFA", "ETFDH", "EWSR1", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6B", "EXOC7", "EXOC8", "EXOSC2", "EXOSC7", "EXOSC9", "EXTL3", "EZR", "F11R", "FABP5", "FAF1", "FAH", "FANCA", "FANCD2", "FANCI", "FARSB", "FASN", "FAU", "FDFT1", "FDPS", "FECH", "FEN1", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIS1", "FKBP10", "FKBP1A", "FKBP2", "FKBP4", "FKBP5", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNTA", "FOXRED1", "FSCN1", "FTO", "FUCA1", "FUS", "FXR1", "FXR2", "G3BP1", "G6PD", "GABARAPL2", "GALNT1", "GAPDH", "GART", "GBA", "GBE1", "GCC2", "GCDH", "GCLM", "GDAP1", "GDI1", "GFPT1", "GGCT", "GGCX", "GGH", "GID4", "GID8", "GIGYF2", "GLA", "GLB1", "GLRX", "GLS", "GLUD1", "GM2A", "GMPPB", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG5", "GNPAT", "GNS", "GOT1", "GOT2", "GPAM", "GPD2", "GPHN", "GPI", "GPS1", "GPT2", "GRB2", "GRSF1", "GSK3A", "GSK3B", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F2", "GTF2I", "GTPBP4", "GTSE1", "GUSB", "GYG1", "GYS1", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HADH", "HADHA", "HADHB", "HAT1", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HEBP1", "HELLS", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HIRIP3", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGCL", "HMGCS1", "HMGN1", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA6", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HTT", "HUS1", "HYOU1", "IARS", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFNGR1", "IFT27", "IFT88", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP3", "IKBKB", "IKBKG", "ILF2", "ILK", "IMP3", "IMPAD1", "IMPDH1", "IMPDH2", "INF2", "INPP4A", "IPO9", "IQGAP1", "IQGAP2", "IRF2BPL", "IRS4", "ITCH", "ITGB1", "ITPA", "IVD", "JUP", "KAT7", "KDM1A", "KDM1B", "KDM3B", "KDSR", "KHDRBS1", "KHSRP", "KIF15", "KIF1B", "KIF20B", "KIF22", "KIF23", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KLC1", "KLC2", "KLC4", "KMT2A", "KPNA1", "KPNA4", "KPNB1", "KTN1", "L2HGDH", "LAMB1", "LAMC1", "LARP1", "LARP7", "LARS2", "LBR", "LDHA", "LDHB", "LDLR", "LDLRAP1", "LEMD3", "LGALS3BP", "LIG1", "LIG3", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMNA", "LMNB1", "LMNB2", "LPGAT1", "LRP1", "LRPPRC", "LRRC59", "LRWD1", "LSM2", "LSS", "LTA4H", "LUC7L", "LZTFL1", "MACF1", "MAD1L1", "MAGED1", "MAGT1", "MANF", "MAP1B", "MAP2K1", "MAP2K3", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCKS", "MARK1", "MARK2", "MARS", "MAT2A", "MAT2B", "MAVS", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDC1", "MDH1", "MDH2", "ME2", "MECP2", "MED1", "MED14", "MEPCE", "METTL3", "MFAP1", "MFN2", "MGST2", "MGST3", "MIA3", "MIF", "MKI67", "MKLN1", "MMAB", "MOGS", "MORF4L1", "MOV10", "MPC2", "MPG", "MPI", "MPP1", "MPP2", "MPST", "MRE11", "MRPL19", "MRPL40", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTDH", "MTERF3", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTMR2", "MTOR", "MTR", "MUT", "MVK", "MYBBP1A", "MYCBP", "MYCBP2", "MYEF2", "MYH10", "MYH9", "MYL6", "MYO1C", "MYO6", "NAA15", "NAA16", "NAA40", "NAA50", "NAE1", "NAGLU", "NAMPT", "NAP1L1", "NAPA", "NARS", "NAT10", "NBN", "NCAPG", "NCAPG2", "NCAPH2", "NCBP1", "NCDN", "NCKAP1", "NCL", "NCOR1", "NCSTN", "ND5", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEFL", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NFATC2IP", "NFKB1", "NIPBL", "NKRF", "NME1", "NME2", "NME3", "NONO", "NOP2", "NPC1", "NPC2", "NSD1", "NSDHL", "NSF", "NT5C3A", "NUBPL", "NUDC", "NUDT21", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP214", "NUP62", "NUP88", "NUP98", "NXF1", "OAT", "OCRL", "OGDH", "OGT", "OPA1", "ORC3", "ORC5", "OSBPL3", "OTUD7B", "OXCT1", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PABPC1", "PABPN1", "PAF1", "PAFAH1B1", "PAICS", "PAIP1", "PAK1", "PAK2", "PAK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PAXIP1", "PBK", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCM1", "PCNA", "PCNT", "PDCD6", "PDCD6IP", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA6", "PDLIM5", "PDLIM7", "PDS5A", "PDS5B", "PEBP1", "PECR", "PELO", "PFAS", "PFDN1", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGRMC2", "PHB", "PHB2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PI4K2A", "PI4KA", "PIBF1", "PIGT", "PIK3C2A", "PIK3C3", "PIK3R4", "PIN1", "PIP4K2B", "PISD", "PKM", "PKN1", "PKN2", "PLCB3", "PLCG1", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PMPCA", "PMVK", "PNKP", "PNP", "PNPLA8", "PNPO", "PNPT1", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "PON2", "POR", "PPAT", "PPIB", "PPID", "PPIF", "PPM1G", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPT2", "PRCC", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKAR2B", "PRKCD", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRPF3", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRRC2C", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPA", "PTPN1", "PTPN11", "PTPN9", "PTPRF", "PTRH2", "PURA", "PUS1", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QKI", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB21", "RAB2A", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABGAP1", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAE1", "RALA", "RAN", "RANBP1", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RBBP7", "RBM14", "RBM17", "RBM39", "RBM4", "RBM47", "RBM5", "RBMX", "RBPMS", "RCC1", "RCN1", "RDH14", "RDX", "RECQL", "RECQL5", "REXO2", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHEB", "RHOA", "RHOG", "RIF1", "RIPK1", "RMND5A", "RNASEH2A", "RNASEH2B", "RNASET2", "RNF14", "RNF20", "RNF40", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPRD1B", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRM2B", "RTCB", "RTF1", "RTN3", "RTN4", "RUVBL1", "S100A10", "S100A11", "SACM1L", "SAFB", "SAMHD1", "SAP18", "SAR1A", "SAR1B", "SARS", "SASS6", "SCAF11", "SCAMP2", "SCARB1", "SCARB2", "SCD", "SCO1", "SCO2", "SCP2", "SCRIB", "SDCBP", "SDF2L1", "SDHA", "SDHB", "SEC23A", "SEC24A", "SEC24C", "SEC31A", "SEL1L", "SELENBP1", "SEPT11", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD7", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SFPQ", "SFSWAP", "SGPL1", "SH3GL1", "SH3GLB1", "SHMT1", "SHMT2", "SHOC2", "SIN3A", "SIRT1", "SKP1", "SKP2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A20", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC30A7", "SLC35B2", "SLC38A2", "SLC3A2", "SLC6A15", "SLIT2", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMS", "SNAP23", "SNAP29", "SND1", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SOAT1", "SOD2", "SORT1", "SPEN", "SPHK2", "SPNS1", "SPPL2A", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRCAP", "SREK1", "SRM", "SRP54", "SRPK1", "SRPK2", "SRRM1", "SRSF1", "SRSF10", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSNA1", "SSR4", "STAG1", "STAG2", "STAM", "STAMBP", "STAT1", "STAT3", "STIP1", "STK4", "STMN1", "STOM", "STRAP", "STRN", "STUB1", "STX4", "STXBP2", "STXBP3", "STXBP4", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUPT5H", "SUZ12", "SYNE1", "SYNE2", "TAB1", "TACO1", "TALDO1", "TAP1", "TARDBP", "TBC1D10A", "TBC1D4", "TBCA", "TBK1", "TBL1XR1", "TBL2", "TCP1", "TECR", "TELO2", "TERF2", "TERF2IP", "TFAM", "TFB1M", "TFCP2", "TFRC", "THRAP3", "TIGAR", "TIMELESS", "TIMMDC1", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLN1", "TMED10", "TMEM126B", "TMEM165", "TMEM43", "TMOD1", "TMOD3", "TMPO", "TMPO", "TNKS1BP1", "TNPO1", "TOLLIP", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOR1AIP1", "TP53", "TP53BP1", "TPI1", "TPM1", "TPM3", "TPM4", "TPMT", "TPP1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRIM25", "TRIM28", "TRIM33", "TRIO", "TRIP13", "TRMT2A", "TSC2", "TSG101", "TSPO", "TSPYL1", "TTC19", "TTC26", "TTF2", "TTI1", "TTK", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWISTNB", "TXN2", "TXNDC5", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UBA1", "UBA3", "UBAP2L", "UBE2G2", "UBE2L3", "UBE2N", "UBE2T", "UBE3A", "UBR5", "UBTF", "UBXN7", "UCHL5", "UCK2", "UFD1", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UPF1", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USMG5", "USP10", "USP5", "USP7", "USP9X", "UTRN", "VAPA", "VAPB", "VARS1", "VBP1", "VCL", "VDAC1", "VDAC2", "VDAC3", "VIM", "VPS18", "VPS33A", "VPS37C", "VPS4A", "WAPL", "WARS", "WASL", "WDHD1", "WDR1", "WDR26", "WDR48", "WDR5", "WFS1", "WIPI2", "WNK1", "XAB2", "XPNPEP3", "XPO1", "XPO5", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YAP1", "YARS", "YARS2", "YBX1", "YBX3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZC3H15", "ZFR", "ZFYVE16", "ZMPSTE24", "ZNF281", "ZNF318", "ZYX"], "leading_proteins": ["ABCB1", "ACAT2", "ACOX1", "ADAM17", "AGPS", "AIFM1", "AKT1", "ANAPC2", "ANXA1", "APC", "ATP2A2", "ATP5L", "ATP6", "B4GALT1", "BAX", "BSG", "BUB1B", "C1QBP", "CALM3", "CARM1", "CASP3", "CDK4", "CDK5", "CDKAL1", "CDKN2A", "CDS2", "CENPE", "CERS2", "CHEK1", "CHKA", "CHST14", "CHUK", "CLPTM1L", "CLUH", "COA3", "COLEC12", "COMT", "COQ8A", "COX11", "COX15", "COX5A", "COX7A2", "CPNE1", "CPT2", "CRK", "CSTB", "CTPS1", "CTPS2", "CTSB", "CYB5B", "CYFIP1", "CYP51A1", "DCTPP1", "DHCR24", "DHCR7", "DHFR", "DIABLO", "DNM1L", "DVL2", "EBP", "ECE1", "EIF4E", "EMD", "EPHX1", "ETFDH", "EXO1", "FASN", "FDFT1", "FIS1", "FKBP10", "FKBP1A", "FKBP2", "FKBP5", "FMR1", "FOXRED1", "FUS", "FXR1", "G6PD", "GBA", "GGCX", "GGH", "GM2A", "GMPPB", "GNPAT", "GRB2", "GSTA4", "GYG1", "HADH", "HK2", "HLA-A", "HLA-C", "HMOX1", "HNRNPAB", "HNRNPH1", "HTT", "ICMT", "IDH2", "IFNGR1", "KDM1B", "KDSR", "KLC1", "LAMC1", "LBR", "LGALS3BP", "LMAN1", "LRP1", "LSS", "LTA4H", "MAPK1", "MAPK14", "MED14", "MFN2", "MIF", "MOGS", "MPP2", "MSMO1", "NAA40", "NAMPT", "NAP1L1", "NDUFA11", "NDUFAF2", "NDUFB1", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS2", "NT5C3A", "P3H1", "P4HA1", "P4HA2", "PAK2", "PAPSS1", "PDCD6", "PDE6D", "PEBP1", "PECR", "PFDN1", "PFDN2", "PLK1", "POLA2", "POLDIP2", "POLE4", "PON2", "PPAT", "PPP2R1A", "PPP2R1B", "PPT2", "PRCC", "PRMT1", "PRMT5", "PSMA1", "PSMA6", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PTDSS1", "PXMP2", "RAB5B", "RAC1", "RAD23A", "RALA", "RIPK1", "RRM2", "RRM2B", "RTN3", "SAP18", "SCAF11", "SCAMP2", "SCARB1", "SCARB2", "SCO1", "SEL1L", "SGPL1", "SHMT1", "SLC19A1", "SLC1A5", "SLC25A15", "SLC25A20", "SLC25A4", "SORT1", "SPPL2A", "SPTLC2", "STAM", "STK4", "TAP1", "TIMMDC1", "TMEM165", "TPM1", "TPM4", "TRAM1", "TSC2", "TSPO", "TYMS", "UBXN7", "UGCG", "UQCR10", "UQCRQ", "VDAC1", "VDAC2", "VIM", "VPS18", "WFS1", "YBX1", "YBX3", "ZMPSTE24"]} \ No newline at end of file diff --git a/opencell_localization/advanced/idx2term.json b/opencell_localization/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..15f802caf6af65652341957c3b7286520a1d9511 --- /dev/null +++ b/opencell_localization/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "er"} \ No newline at end of file diff --git a/opencell_localization/advanced/plot_0.png b/opencell_localization/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..aa749d41394085bf0a859149b80db761950dc201 --- /dev/null +++ b/opencell_localization/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ca29b0777e218a73bc8a6675f9cdf70df07c939b710a7f9b808ed1b2999535cc +size 194269 diff --git a/opencell_localization/basic/idx2term.json b/opencell_localization/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..7f15dd3ea1a5188fd886a0dcdd59a98b516698a9 --- /dev/null +++ b/opencell_localization/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "er", "1": "golgi", "2": "vesicles"} \ No newline at end of file diff --git a/opencell_localization/basic/plot_0.png b/opencell_localization/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..6a05555c4dffb667e44a82b6611beac1fb94c014 --- /dev/null +++ b/opencell_localization/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bc7c447ba4db154fea5f1abb03781b0bdd8be258066f0fcf0db9f13c38a450d0 +size 130204 diff --git a/opencell_localization/basic/plot_1.png b/opencell_localization/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..285159e9852316201fd10be6fe98ca86c60ff89c --- /dev/null +++ b/opencell_localization/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:264205bd18f08097d28b8ef526c7979f6cc9188c19e5404aabe7a35105eafa3c +size 139836 diff --git a/opencell_localization/basic/plot_2.png b/opencell_localization/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..ee14ab6d264d92f88f1f50fe207d2b0df830b442 --- /dev/null +++ b/opencell_localization/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a0b0e1d58a1b24ddd20e46e8a182144926cb3f4e7cf87a04c31790f6f965b87b +size 138770 diff --git a/opencell_localization/consensus.joblib b/opencell_localization/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..0b5a9e044faad615add23cfbe055ec23bf86d0b9 --- /dev/null +++ b/opencell_localization/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:90bc30d3eb7b3cbdac6624367d56126e7d5cd96b94c5ff9788406d6c664e6b6b +size 74804 diff --git a/opencell_localization/df_merge.tsv b/opencell_localization/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..65e6671bb9c40db6c9b94b9e5c76a9ffacd98789 --- /dev/null +++ b/opencell_localization/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +er 28 86 2.4660685298485414 0.0136605195965471 29.17233009708738 87.61893203883496 1.3358083950399515 0.3757472714196316 13.465054065187209 8.223393744963309 2.0429537263872786 0.4010648005920765 0.1033093437214207 0.1535148843700442 0.0492428307595088 8.830598184191495e-06 1.3459419870581391e-06 diff --git a/opencell_localization/metrics.json b/opencell_localization/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..bc1c0dd6ad2baf65b930c2f70f5e9dbca4ab6e45 --- /dev/null +++ b/opencell_localization/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3329, + "annotations_size": 17, + "title": "Average number of proteins per term", + "value": 100.82352941176471 +} \ No newline at end of file diff --git a/opencell_localization/paths.json b/opencell_localization/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..2b2634d42f9577b9003adcc948d8d5060a63fa3f --- /dev/null +++ b/opencell_localization/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/opencell_localization/fragment/C342/C342_val_log2fc"} \ No newline at end of file diff --git a/opencell_localization/result.tsv b/opencell_localization/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..92448289174d4d0c312c3c88fc2ec22f6241ecdb --- /dev/null +++ b/opencell_localization/result.tsv @@ -0,0 +1,5 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +er 0.4938191633357547 2.4660685298485414 0.0136605195965471 0.2085033336086364 0.2322288331413012 86 Q9H6H4,O96005,Q15392,Q06136,Q9Y487,Q14739,O00264,Q07065,P18085,Q969Q5,Q6NUK4,Q16850,Q15041,P48449,Q969V3,P09132,Q8NHH9,O95470,P84085,O15270,O75340,Q15125,Q9P2W9,Q96A33,O15173,Q15363,Q9Y5M8,O95674 28 +mitochondria 0.6695616641541169 1.7841194992261769 0.0744042494218844 0.7313647586817179 0.404486796593005 11 P21796,P45880 2 +golgi 0.3355851373682338 0.702093691763945 0.482620736100817 0.9999863619174116 0.9608286107282378 64 Q8IZA0,Q8IXU6,Q5VW38,P53365,Q9Y487,Q8NBN3 6 +vesicles 0.3542723198857987 0.2701579226540443 0.7870387622978172 0.9999999999961884 1.0 185 Q86Y82,Q9H6H4,O96005,Q15392,Q06136,Q9Y2Q5,Q9P253,Q9UMY4,Q8IZA0,Q96L92,Q93050,P53985,Q92783,P17812,Q6NT16,Q9Y5X3,P41440,O43752,Q8NBN3,Q8IXU6,P48449,Q7Z6M1,Q969T9,Q9UBF8,Q5VW38,P31749,Q969V3,P49257,O95470,P42356,Q15125,O15027,P02786,O15173,Q15363,P61020,O60476,O95674 38 diff --git a/opencell_localization/selections.json b/opencell_localization/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..85ef96d28bf4c5bf6db0fddfae30b10b27127324 --- /dev/null +++ b/opencell_localization/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["big_aggregates", "cell_contact", "centrosome", "chromatin", "cytoplasmic", "cytoskeleton", "er", "focal_adhesions", "golgi", "membrane", "mitochondria", "nuclear_membrane", "nuclear_punctae", "nucleolus_fc_dfc", "nucleolus_gc", "nucleoplasm", "vesicles"], "available_proteins": ["AAMP", "AATF", "ABCE1", "ACLY", "ACTN1", "ACTN4", "ACTR2", "AGAP3", "AHCY", "AHSA1", "AKAP12", "AKAP13", "AKAP8L", "AKR1A1", "AKT1", "AKT1S1", "ALCAM", "ALDH9A1", "ANAPC16", "ANAPC2", "ANKRD17", "ANXA11", "AP2B1", "AP2S1", "APC", "APPL1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP3", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGAP35", "ARID1A", "ARL1", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL6IP5", "ARL8B", "ARPC2", "ARPC3", "ATG3", "ATG4B", "ATG9A", "ATL2", "ATL3", "ATP1A1", "ATP2B1", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATXN10", "ATXN2L", "BAG4", "BAG6", "BAIAP2", "BANF1", "BAZ1A", "BAZ1B", "BCAP31", "BLM", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOP1", "BPNT1", "BRD2", "BRD4", "BTF3", "BUB1", "BUB1B", "BUD23", "BYSL", "C1orf123", "C21orf59", "CAD", "CALD1", "CALM3", "CAMK1", "CAMK2G", "CANX", "CAPRIN1", "CAPZB", "CASP2", "CASP3", "CBX1", "CCAR1", "CCDC22", "CCDC47", "CCDC86", "CCDC93", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CDC23", "CDC27", "CDC37", "CDC42", "CDC42BPB", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK4", "CDK5", "CDKN2A", "CDS2", "CEP170", "CEP250", "CETN2", "CHEK1", "CHEK2", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP4A", "CHMP4B", "CHMP7", "CHUK", "CKAP2", "CKAP4", "CKAP5", "CKB", "CLASP1", "CLASP2", "CLINT1", "CLNS1A", "CLPTM1", "CLTA", "CLTC", "CNN2", "COIL", "COMMD1", "COMMD2", "COPA", "COPB2", "COPE", "COPG1", "COPG2", "COPZ1", "CORO1B", "CORO1C", "CPSF6", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CTBP1", "CTBP2", "CTCF", "CTNNB1", "CTNNBL1", "CTPS1", "CTTN", "CYB5R3", "CYP51A1", "DAD1", "DBNL", "DCP1A", "DCP1B", "DCP2", "DCTN2", "DDB1", "DDOST", "DDX21", "DDX39B", "DDX47", "DDX5", "DDX56", "DDX6", "DHCR24", "DHX37", "DHX9", "DIAPH1", "DKC1", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJC11", "DNAJC2", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DOCK7", "DPH2", "DRG1", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "DYNLL2", "EBNA1BP2", "EBP", "ECT2", "EDC3", "EDC4", "EDF1", "EEA1", "EEF1G", "EFTUD2", "EIF2AK2", "EIF3B", "EIF3E", "EIF3G", "EIF3I", "EIF3K", "EIF3M", "EIF4A1", "EIF4A3", "EIF5", "EMC1", "EMC2", "EMC3", "EMC8", "EMG1", "ENO1", "EPN1", "EPS15", "ESD", "ESYT1", "EWSR1", "EZR", "FAM50A", "FANCA", "FASN", "FAU", "FBL", "FDPS", "FKBP5", "FKBP8", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAK", "GAPDH", "GAR1", "GBF1", "GDI1", "GDI2", "GET4", "GNL2", "GNL3", "GOLGA2", "GOLT1B", "GORASP2", "GPR107", "GRB2", "GSK3A", "GSK3B", "GSPT1", "GTF2F1", "GTPBP4", "GYG1", "GYS1", "H1F0", "HDAC1", "HDAC2", "HEATR3", "HGS", "HIP1", "HLA-A", "HMGA1", "HMGB2", "HMGCS1", "HMGN2", "HNRNPA0", "HNRNPC", "HNRNPD", "HNRNPH1", "HNRNPL", "HNRNPU", "HSP90AA1", "HSP90AB1", "HSPA14", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPB1", "HSPBP1", "HSPH1", "HUS1", "IDI1", "IGF1R", "IGF2BP1", "IGF2BP3", "IKBKB", "ILF3", "ILK", "IMP3", "INPP4A", "INTS14", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IST1", "ITSN2", "KDSR", "KIAA0319L", "KIAA0368", "KIF11", "KIF1B", "KIF20A", "KIF22", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KLC1", "KLC2", "KLC4", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "LAMP1", "LAMP2", "LAMTOR2", "LARP7", "LBR", "LDHA", "LDHB", "LEMD2", "LEMD3", "LIG1", "LMAN1", "LMNA", "LMNB1", "LPCAT1", "LSM14A", "LSM14B", "LSS", "LTV1", "LZTS2", "MAN1A2", "MAP2K1", "MAP2K3", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MARK2", "MBOAT7", "MCM10", "MDH1", "MECP2", "MED14", "MED21", "MED24", "MED4", "METAP2", "MFN1", "MFN2", "MIF", "MKI67", "MMGT1", "MPHOSPH10", "MRTO4", "MSH6", "MSN", "MTMR2", "MTOR", "MVK", "MYBBP1A", "MYH10", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO6", "NANS", "NAPA", "NAPG", "NCAPH", "NCKAP1", "NCL", "NCLN", "NECAP1", "NECAP2", "NEK9", "NEMF", "NFKB1", "NHP2", "NIFK", "NMD3", "NOL10", "NOL11", "NOM1", 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b/panther_protein_class/df_merge.tsv @@ -0,0 +1,13 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +transporter 14 57 3.323338526612815 0.000889469011307 16.281553398058254 57.34708737864078 1.7781248355514696 0.2510912048406951 6.627271511266295 3.5084386843827997 1.4364723564792363 0.3433005081320681 3.7735974014023553e-05 0.0002562264911922 0.0001363362205479 0.0005509327657825 0.0005512742936687 +serine protease 8 16 2.963065898077724 0.0030459135300842 5.662621359223301 17.516990291262136 1.1445634795625386 0.1820139001244477 2.0809494011218104 1.6626107291843584 1.568325484830445 0.2384821649427795 0.0068431745235252 0.0239365913087713 7.178515274085645e-06 0.0001661825272043 0.000525961744528 +transferase 9 32 2.529895665584941 0.0114096449107561 7.575242718446602 30.33252427184466 0.4228659702770393 0.5466612075921934 3.0555803938089245 3.1078682540227365 0.8877488356833944 0.3204543659632313 0.0418077700406093 0.0118439766153403 0.0681445056645133 0.0874034435153755 0.0197354712578867 +metalloprotease 12 26 2.453894598722159 0.0141318396320799 8.58495145631068 26.398058252427184 1.4262736372921438 0.246779453311036 3.321022586051017 1.6463540525991265 1.1083706824215755 0.2918245458017476 0.3506820174100548 0.2336798458054532 0.0154029461510805 0.0018945002996002 0.000242432708797 +primary active transporter 7 22 2.4083626604401123 0.0160242541623545 8.614077669902912 23.45631067961165 1.2392440710771837 0.271771563990288 4.792195908457348 3.1431129799052804 1.4794913205770832 0.3014776193450941 0.086864214346425 0.0369748680428621 0.0222198796395938 0.1912240791272418 0.030712608331405 +acyltransferase 4 18 2.393035034130941 0.0167096454633097 5.550970873786408 17.609223300970875 0.8395368249042097 0.3495065414698917 3.0409541216574527 2.8086572783837886 1.152491475155923 0.3107783941454108 0.0437331415032988 1.0 0.0077496201950681 0.003336200398636 0.0038723946410938 +esterase 2 8 2.3266973477292856 0.019981379125884 2.0679611650485437 7.684466019417476 0.7172320192268422 0.3647762514846939 1.5217653004191571 1.4253091833924298 1.0863934099472772 0.3032327374846778 0.0129905487867928 0.0051137089586154 0.0190005699483642 0.0155574138143109 0.0896340654819229 +oxygenase 2 7 2.1215576637483013 0.0338749007708911 3.138349514563106 6.771844660194175 1.5409868347565758 0.1477866581414416 1.2914149665013366 1.041089559555361 1.2379399582807478 0.2357869798067575 0.0153631225051974 0.1114073342812727 0.0224191931510111 0.0197332243190265 0.1098061730973064 +protein modifying enzyme 9 28 2.08289451059372 0.037260840099631 6.487864077669903 24.82281553398058 0.9737051724681342 0.3238157719208961 2.575528657386725 2.871041189126622 1.1448244681235864 0.2930923238696635 0.371181177773541 1.0 0.4330643878145832 0.0027389701542927 0.0004436609938217 +membrane trafficking regulatory protein 4 22 2.066936708690602 0.0387401181733428 4.949029126213592 18.78640776699029 1.0645815505395402 0.2320552342124929 2.3097144002673033 2.893415643517755 1.4460865220385617 0.2677048300346334 0.0085060135189794 0.0021878047045258 0.0146485330026984 0.0395157416890983 0.1154104084629905 +ATP synthase 3 20 1.969086570725048 0.0489431507079516 6.381067961165049 20.483009708737864 0.8573640874951715 0.3249378356888472 2.8850015270213047 1.3977105655851854 1.2517106680730556 0.3017789026221172 0.2193453647012636 0.141543756104335 0.2613412907301976 0.0064140084647031 0.0623633603808868 +phosphatase modulator 1 7 1.9650906870592415 0.0494037423060922 2.558252427184466 6.218446601941747 -0.1837647178339747 0.5280012572207944 1.4988684581133591 1.4179328296095586 0.9225254272907308 0.3099841961920083 1.0 1.0 1.0 0.1227655047468798 0.3470060894740981 diff --git a/panther_protein_class/metrics.json b/panther_protein_class/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..70af606b4bb9693239b33e1721ef0d8df5cf2c4f --- /dev/null +++ b/panther_protein_class/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3329, + "annotations_size": 159, + "title": "Average number of proteins per term", + "value": 14.20125786163522 +} \ No newline at end of file diff --git a/panther_protein_class/paths.json b/panther_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..4d90fc95028bfffc8847c027104003af62e2119c --- /dev/null +++ b/panther_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/panther_protein_class/fragment/C342/C342_val_log2fc"} \ No newline at end of file diff --git a/panther_protein_class/result.tsv b/panther_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..eb83c5172cc91cb2697b4e970fb7ceb7bc31ce4c --- /dev/null +++ b/panther_protein_class/result.tsv @@ -0,0 +1,48 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +transporter 0.6302918822622979 3.323338526612815 0.000889469011307 0.1319348477574961 0.1414255727978199 57 O95373,Q99595,Q15070,Q9HAV4,Q9HD45,Q9Y619,Q9H2D1,O43772,Q9NR77,O15397,P41440,Q92973,Q567V2,Q99805 14 +serine protease 0.8093897772452248 2.9630658980777236 0.0030459135300842 0.3843270124476818 0.1645993938924275 16 Q16740,Q9HB40,Q4J6C6,P42785,Q9H3G5,P10619,P48147,Q8N2K0 8 +transferase 0.6161530841145723 2.529895665584941 0.0114096449107561 0.8387117676741709 0.2415303298787504 32 O15217,Q9Y5P6,P43490,P37268,O43505,Q8NCH0,Q8NFF5,Q06203,O95674 9 +metalloprotease 0.6268204881446845 2.453894598722159 0.0141318396320799 0.8959611135278651 0.2415303298787504 26 Q7Z2K6,O75844,P02786,O95630,Q9UIQ6,P42892,P55786,Q96TA2,Q9NZ08,Q99797,Q9BYT8,Q5JRX3 12 +primary active transporter 0.6461792728293865 2.4083626604401123 0.0160242541623545 0.9233488670422164 0.2415303298787504 22 Q9BUN8,P09132,P16615,Q9NS69,Q6P4A7,O60888,Q8N4H5 7 +acyltransferase 0.6743959128599056 2.393035034130941 0.0167096454633097 0.931387559826958 0.2415303298787504 18 Q8NCC3,P23786,P49356,Q9BWD1 4 +esterase 0.82661489779703 2.3266973477292856 0.019981379125884 0.9596114661691526 0.2591580346314158 8 Q969T7,Q9NUJ1 2 +oxygenase 0.8262803744362717 2.1215576637483013 0.0338749007708911 0.9958283773102576 0.2872377759831216 7 P30519,P09601 2 +protein modifying enzyme 0.5644928401806883 2.08289451059372 0.037260840099631 0.9976128850422924 0.2872377759831216 28 P50897,Q92791,Q86YN1,P13674,Q9UMR5,O75718,O60725,O60476,O15460 9 +membrane trafficking regulatory protein 0.590820674214713 2.066936708690602 0.0387401181733428 0.9981306528131092 0.2872377759831216 22 Q14108,O43731,Q8WTV0,P24390 4 +ATP synthase 0.5853060368949888 1.969086570725048 0.0489431507079516 0.9996573664078696 0.312494313875069 20 P00846,O75964,Q9Y487 3 +phosphatase modulator 0.7890752658837422 1.9650906870592415 0.0494037423060922 0.999682765846858 0.312494313875069 7 P30154 1 +G-protein coupled receptor 0.9258742121081333 1.8291928065822551 0.0673707296878789 0.9999847335659612 0.3371550799193019 4 Q9NPR9,Q8NBN3 2 +transmembrane signal receptor 0.68045696267262 1.7745050847618309 0.0759796417718881 0.9999965056626656 0.3371550799193019 9 O15173,Q8WUJ1,Q9UMX5 3 +protease 0.4745999363492851 1.7583219814876347 0.0786927395897478 0.9999978106535496 0.3381660971559435 42 P28070,Q9UJ14,P25786,P20618,P28074,P49721,P28072,O75976 8 +mitochondrial carrier protein 0.7771496672196548 1.7332533027426051 0.0830506567514524 0.999998969828188 0.3475014321968666 6 Q9BSK2,Q70HW3,Q9Y6C9 3 +calmodulin-related 0.5922270776567891 1.6888521871633193 0.0912477599125753 0.9999997529222652 0.3621962232293695 14 Q02818,P80303 2 +oxidase 0.580682113951015 1.673399567976053 0.0942486628539123 0.9999998539745908 0.3621962232293695 15 Q8NB78,O75880,Q15800,P14406 4 +oxidoreductase 0.4564202825865614 1.6347884923306204 0.1020933939683339 0.9999999633768656 0.3621962232293695 43 O43676,Q8N4Q0,Q6DKJ4,O95831,Q15067,O75306,O95168,Q8N0U8,Q16134,Q86Y39,O43169,O14949 12 +transfer/carrier protein 0.6449790632711264 1.6328158105797266 0.1025077407971433 0.9999999659683404 0.3621962232293695 10 Q5T8D3,P12235,P17900 3 +secondary carrier transporter 0.6449784577078584 1.6328128432668565 0.1025083650649159 0.9999999659721038 0.3621962232293695 10 Q9UJS0,Q9UBX3,Q02978,Q6NT16,P55011 5 +G-protein 0.6955439394180718 1.560063578066598 0.1187448575098975 0.9999999981329128 0.3885655308351876 7 Q9NTK5,P18085 2 +voltage-gated ion channel 0.9371486523604726 1.525808329059893 0.1270576057990109 0.9999999995862784 0.3961207710204458 3 P21796 1 +SNARE protein 0.6031546110429364 1.453590110882689 0.1460599802616338 0.9999999999874988 0.4329534075657151 11 O43752,O95721,Q9P2W9 3 +viral or transposable element protein 0.8967435457633377 1.3754489720715253 0.1689922953069043 0.9999999999998352 0.4713995605929436 3 Q9NUD5 1 +damaged DNA-binding protein 0.7946670191093778 1.325578986719625 0.1849791903420987 0.9999999999999925 0.4985032417693848 4 Q9NQE9 1 +chaperone 0.3649750222535852 1.187966120067794 0.2348467578713957 1.0 0.5936823345718201 74 P62942,P46379,Q9Y2R0,Q9Y680,Q02790,Q9NWM8 6 +phosphatase 0.4782448854334714 1.1590539948537013 0.2464341766147177 1.0 0.5936823345718201 17 Q9H773 1 +kinase 0.4449045599435441 1.1017754762572338 0.2705592944840234 1.0 0.6234627220718799 22 Q9UBF8,Q9BRR6,P52789,P42356,P35790 5 +translation factor 0.6227804020729872 1.0859398889712009 0.2775055876015799 1.0 0.6242253487101886 6 P51116,P51114 2 +major histocompatibility complex protein 0.8105832832230833 1.056688171025116 0.2906539253341229 1.0 0.6330681387414459 3 P04439,P10321 2 +methyltransferase 0.4467181495486348 0.961702190353486 0.336199221788209 1.0 0.6766541299281675 17 Q86VU5,Q9BV86,P34896,P21964,P34897,P22061 6 +amino acid transporter 0.648214711591101 0.7686792834571751 0.4420837261492045 1.0 0.7640360049752557 4 O14925 1 +ATP-binding cassette (ABC) transporter 0.5072536606134475 0.7190498380626864 0.4721102127261296 1.0 0.7901634086679433 7 Q03518 1 +hydrolase 0.3844333801466643 0.7018735062825414 0.4827580525963904 1.0 0.7995680246127715 23 Q9BQG2,P07099,O60502 3 +cysteine protease 0.3704905376323748 0.6216771093108017 0.5341542063395641 1.0 0.8261712263951168 24 Q96FW1,Q92820,P07858,Q96K76,Q13510 5 +phospholipase 0.4410081800875465 0.5967244610066418 0.5506913584886133 1.0 0.8281424503006108 9 Q8NHP8,Q8IV08 2 +lyase 0.3797248053614469 0.4684326765289548 0.639475204917817 1.0 0.8699525525229903 14 Q9UHG3,P53701 2 +scaffold/adaptor protein 0.3088837954908457 0.4314357324712949 0.6661515730157652 1.0 0.8760503572419948 85 Q5SW96,P07602,Q96F07,Q9NZW5,O60828,O43823,Q96L92,Q92783,Q9Y5X3,Q9UQB8,Q5BKZ1,P57105,Q9Y2I1,Q9ULX6,Q7L576,P35613,Q9Y639,Q96CX2,O14641,P46108,Q14168,Q9Y2W6 22 +GTPase-activating protein 0.3292102294891178 0.3192369373660931 0.7495468491889341 1.0 0.9232972867291828 22 O60343,Q13576,Q66K14,Q8TC07,Q0IIM8,Q9BXI6 6 +nucleic acid metabolism protein 0.5010526315789505 0.2949737600098239 0.7680139248045128 1.0 0.9251076821508905 4 Q96FV9,P49750,Q9Y2W1 3 +Hsp90 family chaperone 0.4769924812030113 0.2356555207535914 0.8136999871484265 1.0 0.9443671383693416 4 P08238,P14625,P07900 3 +peroxidase 0.4301322558726993 0.1404265663657539 0.8883229688911054 1.0 0.989668808615769 4 P30048 1 +glucosidase 0.4796340357925899 0.124442873867426 0.9009646287146058 1.0 0.9948151108723772 3 Q13724 1 +transaminase 0.324838130490329 0.1063397216691592 0.9153128169087354 1.0 1.0 10 O15270 1 +ion channel 0.3555946430607503 0.0948850375673935 0.924406141185693 1.0 1.0 5 Q96S66 1 +vesicle coat protein 0.2846527718733939 0.0646213436472166 0.948475490453598 1.0 1.0 24 P53365,Q15363 2 diff --git a/panther_protein_class/selections.json b/panther_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..604aec2b57cbdc4503fe478972e8b97133f3a8e8 --- /dev/null +++ b/panther_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthase", "ATP-binding cassette (ABC) transporter", "C2H2 zinc finger transcription factor", "DNA glycosylase", "DNA helicase", "DNA ligase", "DNA metabolism protein", "DNA methyltransferase", "DNA polymerase processivity factor", "DNA topoisomerase", "DNA-binding transcription factor", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "G-protein", "G-protein coupled receptor", "G-protein modulator", "GTPase-activating protein", "Hsp90 family chaperone", "P53-like transcription factor", "RNA helicase", "RNA metabolism protein", "RNA methyltransferase", "RNA processing factor", "RNA splicing factor", "Rel homology transcription factor", "SNARE protein", "acetyltransferase", "actin and actin related protein", "actin binding motor protein", "actin or actin-binding cytoskeletal protein", "acyltransferase", "aldolase", "amino acid kinase", "amino acid transporter", "aminoacyl-tRNA synthetase", "amylase", "apolipoprotein", "aspartic protease", "basic leucine zipper transcription factor", "cadherin", "calcium-binding protein", "calmodulin-related", "carbohydrate kinase", "cell adhesion molecule", "centromere DNA-binding protein", "chaperone", "chaperonin", "chromatin/chromatin-binding, or -regulatory protein", "cyclase", "cysteine protease", "cytokine", "cytoskeletal protein", "damaged DNA-binding protein", "deacetylase", "deaminase", "decarboxylase", "defense/immunity protein", "dehydratase", "dehydrogenase", "endodeoxyribonuclease", "endoribonuclease", "epimerase/racemase", "esterase", "exodeoxyribonuclease", "exoribonuclease", "extracellular matrix glycoprotein", "extracellular matrix protein", "extracellular matrix structural protein", "galactosidase", "general transcription factor", "glucosidase", "glycosidase", "glycosyltransferase", "growth factor", "guanyl-nucleotide exchange factor", "heterotrimeric G-protein", "histone", "histone modifying enzyme", "homeodomain transcription factor", "hydratase", "hydrolase", "hydroxylase", "immunoglobulin superfamily cell adhesion molecule", "integrin", "intercellular signal molecule", "intermediate filament binding protein", "ion channel", "isomerase", "kinase", "kinase activator", "kinase inhibitor", "kinase modulator", "ligase", "lipase", "lyase", "mRNA capping factor", "mRNA polyadenylation factor", "major histocompatibility complex protein", "membrane traffic protein", "membrane trafficking regulatory protein", "metalloprotease", "methyltransferase", "microtubule binding motor protein", "microtubule or microtubule-binding cytoskeletal protein", "mitochondrial carrier protein", "mutase", "non-motor actin binding protein", "non-motor microtubule binding protein", "non-receptor serine/threonine protein kinase", "nucleic acid metabolism protein", "nucleotide kinase", "nucleotide phosphatase", "nucleotidyltransferase", "oxidase", "oxidoreductase", "oxygenase", "peptide hormone", "peroxidase", "phosphatase", "phosphatase activator", "phosphatase modulator", "phosphodiesterase", "phospholipase", "primary active transporter", "primase", "protease", "protease inhibitor", "protein modifying enzyme", "protein phosphatase", "protein-binding activity modulator", "pyrophosphatase", "reductase", "replication origin binding protein", "ribosomal protein", "scaffold/adaptor protein", "secondary carrier transporter", "serine protease", "small GTPase", "structural protein", "tight junction", "transaminase", "transcription cofactor", "transfer/carrier protein", "transferase", "transketolase", "translation elongation factor", "translation factor", "translation initiation factor", "translation release factor", "translational protein", "transmembrane signal receptor", "transporter", "tubulin", "tyrosine protein kinase receptor", "ubiquitin-protein ligase", "vesicle coat protein", "viral or transposable element protein", "voltage-gated ion channel", "zinc finger transcription factor"], "available_proteins": ["AACS", "AAK1", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB7", "ABCC4", "ABCD3", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD6", "ACAA1", "ACAA2", "ACAD11", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ADA", "ADAM17", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKT1", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG13", "ALG5", "ALKBH1", "ALKBH5", "ALYREF", "ANAPC1", "ANAPC7", "ANKFY1", "ANKHD1", "ANKRD17", "ANLN", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APEH", "APOBEC3C", "APPL1", "APRT", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP3", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP35", "ARHGAP5", "ARHGDIA", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL6", "ARL6IP5", "ARMC9", "ARPC1A", "ARPC1B", "ARPC3", "ARPC4", "ARVCF", "ASAH1", "ASB6", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD2", "ATAD5", "ATE1", "ATF7IP", "ATG3", "ATG4B", "ATL2", "ATL3", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "ATPAF1", "ATPIF1", "ATRX", "ATXN2", "ATXN2L", "AUP1", "B3GALT6", "B4GALT1", "B4GAT1", "BAG2", "BAG6", "BAIAP2", "BCAP31", "BCAS2", "BCAT2", "BCLAF1", "BDH2", "BLM", "BLMH", "BLOC1S1", "BLVRA", "BLVRB", "BOP1", "BPNT1", "BRCA1", "BRIX1", "BSG", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BZW1", "BZW2", "CACTIN", "CACYBP", "CAD", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAP2", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CASK", "CASP2", "CASP3", "CAST", "CBL", "CBR1", "CCAR1", "CCAR2", "CCDC88A", "CCDC94", "CCNA2", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CD3EAP", "CD47", "CDC23", "CDC25C", "CDC27", "CDC37", "CDC42", "CDC42BPB", "CDC45", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK4", "CDK5", "CDK6", "CDKN2AIP", "CDS2", "CDX2", "CEBPZ", "CENPB", "CEP170", "CEP250", "CETN2", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHEK1", "CHEK2", "CHERP", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP4A", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLGN", "CLIC1", "CLIC4", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLTA", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT3", "CNOT7", "CNP", "COA3", "COASY", "COG4", "COIL", "COLEC12", "COLGALT1", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "CORO1B", "CORO1C", "COTL1", "COX11", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSE1L", "CSNK1A1", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTH", "CTNNA1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWC22", "CYB5B", "CYB5D2", "CYB5R3", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DBN1", "DBNL", "DBT", "DCAF8", "DCAKD", "DCP1A", "DCP1B", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCXR", "DDB1", "DDI2", "DDOST", "DDT", "DEK", "DENR", "DERL1", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHODH", "DHRS1", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DIS3L2", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC21", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUSP12", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBP", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC4", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EGFR", "EHD1", "EHD4", "EIF2A", "EIF2AK2", "EIF2AK4", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELOB", "ELOC", "ELP1", "EMC2", "EMG1", "ENAH", "ENO1", "ENO2", "EPHX1", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERH", "ERI1", "ERMP1", "ERO1A", "ERP29", "ESD", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC1", "EXOC3", "EXOC4", "EXOC5", "EXOC6B", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXTL3", "EZR", "FAHD1", "FAM98A", "FAM98B", "FARSA", "FARSB", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FKBP14", "FKBP1A", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FMR1", "FNDC3A", "FNTA", "FNTB", "FOXRED1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATAD2A", "GATAD2B", "GATB", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLM", "GCN1", "GDI1", "GDI2", "GDPD1", "GFPT1", "GGH", "GGT7", "GID8", "GLA", "GLB1", "GLDC", "GLMN", "GLO1", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNE", "GNG5", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLT1B", "GOPC", "GOT1", "GOT2", "GPAM", "GPATCH4", "GPD2", "GPI", "GPKOW", "GPN1", "GPR107", "GPR108", "GPR89B", "GPT2", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP3", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADHB", "HARS2", "HAT1", "HBS1L", "HCCS", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HECTD1", "HERC4", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HM13", "HMBS", "HMGA1", "HMGCL", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HTATSF1", "HUS1", "HUWE1", "IARS", "IARS2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFNGR1", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPA1", "IMPAD1", "IMPDH1", "IMPDH2", "INTS11", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "ISCU", "ISG20L2", "ISOC1", "ISOC2", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITSN2", "IVD", "JMJD6", "KARS", "KAT7", "KCTD12", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0368", "KIF11", "KIF14", "KIF15", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIFC1", "KLC1", "KLC2", "KLC4", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRR1", "L2HGDH", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LBR", "LCMT1", "LDHA", "LDHB", "LDLR", "LDLRAP1", "LETM1", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LNPEP", "LONP1", "LPCAT1", "LPGAT1", "LRP1", "LRPAP1", "LRRC40", "LRRC47", "LRRC59", "LRWD1", "LSM14A", "LSM14B", "LSM2", "LSM6", "LSS", "LTN1", "LYAR", "LYPLA1", "LYPLAL1", "LZTFL1", "M6PR", "MACF1", "MAGED1", "MAGED2", "MAGT1", "MAN1A2", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K3", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCH5", "MARK1", "MARK2", "MARS", "MAT2A", "MAT2B", "MBOAT7", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MDH1", "MDH2", "ME2", "MECP2", "MED1", "MED14", "MED21", "MED23", "MED24", "MED4", "METAP1", "METAP2", "METTL1", "METTL13", "METTL16", "METTL3", "MFAP1", "MFSD5", "MGAT1", "MGEA5", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINPP1", "MIPEP", "MKRN2", "MMAB", "MMS19", "MOB4", "MOGS", "MORF4L1", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL22", "MRPL23", "MRPL28", "MRPL3", "MRPL37", "MRPL39", "MRPL4", "MRPL40", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL50", "MRPL55", "MRPL58", "MRPL9", "MRPS10", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTHFS", "MTIF2", "MTMR2", "MTOR", "MTPAP", "MTSS1L", "MUT", "MVK", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA16", "NAA35", "NAA50", "NAE1", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCBP1", "NCDN", "NCOA5", "NCOR1", "ND5", "NDC80", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFB1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NENF", "NFKB1", "NFS1", "NHP2", "NIP7", "NIPBL", "NISCH", "NIT2", "NKRF", "NKTR", "NLN", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOC4L", "NOL6", "NOL9", "NOM1", "NONO", "NOP14", "NOP56", "NOP58", "NOP9", "NOVA1", "NPEPPS", "NPM1", "NPTN", "NRBP1", "NRDC", "NSDHL", "NSF", "NSFL1C", "NSUN2", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP153", "NUP155", "NUP160", "NUP210", "NUP214", "NUP37", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "NXN", "OAT", "OCIAD1", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC3", "ORC5", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OXA1L", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B2", "PAFAH1B3", "PAIP1", "PAK1", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PAPOLA", "PARG", "PARN", "PARP1", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PCYOX1", "PDCD11", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXK", "PDZD8", "PEBP1", "PECR", "PELO", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGGT1B", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHF10", "PHF3", "PHF6", "PHGDH", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGL", "PIK3C2A", "PIK3C3", "PIK3R4", "PIN1", "PINX1", "PIP4K2B", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCB3", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNP", "PNPLA6", "PNPLA8", "PNPO", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKAR2B", "PRKCD", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF39", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", 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"RHOT2", "RIDA", "RIF1", "RIPK1", "RNASEH2A", "RNF14", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPF1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD2", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRM2B", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCA", "S100A10", "S100A11", "S100A13", "SAAL1", "SACM1L", "SAE1", "SAMHD1", 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0000000000000000000000000000000000000000..58eace71d379e653f301f34f739e8b1cf6d84845 --- /dev/null +++ b/pharos_dto/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:47d7bd9587b4423ce5b9d1b80b1199a7e50e945e6a5cc5c24adaea8a7cced286 +size 383038 diff --git a/pharos_dto/df_merge.tsv b/pharos_dto/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..cecf9809c5363d322fc9f8771695bf966055b2b5 --- /dev/null +++ b/pharos_dto/df_merge.tsv @@ -0,0 +1,11 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +SLC superfamily of solute carriers 15 40 3.4907287007859407 0.0004817051344461 18.888349514563107 44.33009708737864 2.1618907004737498 0.1690913715307362 9.633686860107934 5.825351940723624 1.7350998035598977 0.2760301582542676 9.354880407839148e-05 0.0119412685134754 6.56910300834816e-05 0.0048808645423337 0.0164128898582906 +SLC25 family of mitochondrial transporters 8 20 3.064744677101647 0.0021785589299352 9.148058252427184 20.71359223300971 2.0411027534642088 0.1411881998864352 5.368907349966936 1.8276489510009888 1.309103123363054 0.2428184236965967 9.97568501319562e-06 0.0007667347448651 2.656375344257793e-05 0.0002406237069856 5.3690164151697385e-05 +Receptor 9 30 2.838812093493027 0.0045281813720909 8.25242718446602 27.344660194174757 1.739519175745715 0.1905542238199536 2.855648283399814 4.245230977176689 1.1861053756197322 0.2707159726336181 0.0015129853104069 0.0017602267192959 0.0005613056131664 0.0146839520149879 0.0142204971286994 +Signaling 8 17 2.6024751777414528 0.009255351488091 5.66747572815534 18.009708737864077 1.330299096012152 0.2668377480945127 2.507969905227609 1.6994867622232877 1.0107551340834326 0.2926688105318188 0.5058485752328652 0.3523884632837075 0.5778229381468787 0.3618702667758764 0.430842291080988 +Reductase 7 17 2.502414392232569 0.0123349452789731 4.563106796116505 16.313106796116504 1.2016212969729014 0.3130807121312539 1.9089462498224232 1.180966799206311 0.8349037556988175 0.2876306629725971 0.0015207949208565 0.0003706576678266 0.0027014769688677 5.7864269479668425e-05 5.2876838988133375e-05 +Mitochondrial nucleotide transporter subfamily 3 8 2.390152358034638 0.016841384690859 4.216019417475728 9.065533980582524 1.5870110662923598 0.1668197633609344 2.720728714423222 1.1029864386277723 1.1616247375257451 0.2431804664231326 0.0002051665230549 0.0711332726649859 0.0003712110430798 0.005208827916976 0.004988841333209 +Esterase 4 12 2.345676662800112 0.018992575578435 2.4199029126213594 10.856796116504857 0.6548503739556798 0.3454832165784889 1.4749994208625692 1.2546524785480109 1.099568757577031 0.2732488393636652 0.1198919526526125 0.0756950383436983 0.144637307685789 0.000493734331549 0.0007595134217252 +Mitochondrial amino acid transporter subfamily 1 6 2.020941309671981 0.0432858409461489 1.75 5.106796116504855 1.5314439851709 0.1644824524943633 1.357512359363716 0.7195281808878056 0.8276270779181836 0.2049815877367878 0.0016921469275669 0.000647621121882 0.0025156479029566 0.014977467250991 0.0548161530025184 +Protease 44 117 2.003582544899071 0.0451147971998853 23.87864077669903 112.97330097087378 0.5565894930811873 0.44121745363286 8.615285022365173 8.917462185063522 1.4311973593718734 0.3778605174872721 0.0244338203273235 0.0488673868382216 8.664918472896504e-05 0.0005224805313509 3.1549212355482373e-07 +Metalloprotease 13 38 2.002290466693201 0.0452535007256535 10.080097087378642 37.81310679611651 1.0846602244748076 0.3802793741361127 4.2814674000125414 2.184793664748831 0.9789887795730944 0.3416347995760264 0.4425168834427829 0.3024216363859021 0.0338721796728873 0.0085250028508827 0.0027467368946656 diff --git a/pharos_dto/metrics.json b/pharos_dto/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..13ebff31d2766971a98660d895603e0b74182999 --- /dev/null +++ b/pharos_dto/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3329, + "annotations_size": 2080, + "title": "Average number of proteins per term", + "value": 3.1514423076923075 +} \ No newline at end of file diff --git a/pharos_dto/paths.json b/pharos_dto/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..501af34ec2c4f7f699754618f8a4fa8efe7e5d4a --- /dev/null +++ b/pharos_dto/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_dto/fragment/C342/C342_val_log2fc"} \ No newline at end of file diff --git a/pharos_dto/result.tsv b/pharos_dto/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..d42c72d9e3117cd77ae40dfee661b8a5bc9c26f8 --- /dev/null +++ b/pharos_dto/result.tsv @@ -0,0 +1,74 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +SLC superfamily of solute carriers 0.7178963731272188 3.4907287007859407 0.0004817051344461 0.6329246279582865 0.0627296017158831 40 Q9BSK2,Q8IXU6,Q9H2D1,Q9Y619,Q9UBX3,Q96QD8,P12235,Q02978,O43772,Q9HC07,Q6NT16,Q9Y6C9,P41440,Q70HW3,O95563 15 +SLC25 family of mitochondrial transporters 0.7748299248894673 3.064744677101647 0.0021785589299352 0.9892875184637396 0.0627296017158831 20 Q9BSK2,Q9H2D1,Q9Y619,P12235,Q02978,O43772,Q70HW3,Q9Y6C9 8 +Receptor 0.6718723694070854 2.838812093493027 0.0045281813720909 0.9999205201042092 0.0627296017158831 30 Q9HAV4,Q9NUJ3,Q9UQB8,Q8WTV0,Q9NR77,A6NIH7,Q567V2,Q14108,Q9Y639 9 +Signaling 0.7256616565043856 2.6024751777414528 0.009255351488091 0.9999999960151758 0.0641409238938007 17 Q96PC5,O14641,P43490,P51858,Q8WUJ1,Q5SW96,O15173,O00264 8 +Reductase 0.7071473995215086 2.502414392232569 0.0123349452789731 0.9999999999938602 0.0701699479330539 17 P00374,Q9UBM7,Q15392,Q9UDW1,O95881,Q14739,Q7LG56 7 +Mitochondrial nucleotide transporter subfamily 0.8414135976745841 2.390152358034638 0.016841384690859 0.9999999999999996 0.0788924726691054 8 Q9BSK2,Q70HW3,Q9H2D1 3 +Esterase 0.7642978164865883 2.345676662800112 0.018992575578435 1.0 0.0826515061393923 12 P50897,Q969T7,Q9H0P0,Q9UMR5 4 +Mitochondrial amino acid transporter subfamily 0.84820104292614 2.020941309671981 0.0432858409461489 1.0 0.1269880806318615 6 Q9Y619 1 +Protease 0.4708259598904014 2.003582544899071 0.0451147971998853 1.0 0.1301026221122673 117 O75844,Q92945,Q8NHP8,Q9UIQ6,P42785,Q5BJF2,Q9Y4E8,Q96AE4,P42574,Q9NRF8,P61978,Q96FW1,Q8TC07,P17812,Q0IIM8,Q92820,Q9HA65,Q9BXI6,Q96K76,Q99797,P48147,Q13510,Q7Z2K6,Q8TCT8,Q06210,O95630,Q9HB40,P67812,P42892,P07858,Q96TA2,Q92905,Q9NZ08,Q9H3G5,P10619,Q9BYT8,Q06203,Q8N2K0,O60343,P02786,Q66K14,P55786,Q86TI2,Q5JRX3 44 +Metalloprotease 0.5190090786339574 2.002290466693201 0.0452535007256535 1.0 0.1301898776063063 38 Q7Z2K6,O75844,P02786,O95630,Q9UIQ6,P42892,P55786,Q96TA2,Q92905,Q99797,Q9NZ08,Q9BYT8,Q5JRX3 13 +Acyltransferase 0.6709743083014422 1.88875212998732 0.0589250498559481 1.0 0.1542366914211058 12 P53609,Q9UJ14,P49356 3 +Calcium-binding protein 0.5697514224441032 1.8447634534840396 0.0650719559081536 1.0 0.1642593061759217 19 Q02818,P80303,P43307 3 +Extracellular structure 0.6840484433591197 1.791589574912383 0.0731987343002136 1.0 0.1750801248208857 9 Q9Y2T2,O75718,Q32P28,Q92791 4 +Methyltransferase 0.6018998564439632 1.7427515137363656 0.0813770290917217 1.0 0.1870322878572168 14 Q86VU5,Q08J23,Q9BV86,P21964,P34896,P34897,P22061 7 +F-type and V-type ATPases 0.590220648878508 1.7278284884721509 0.0840189782314724 1.0 0.1895141899828564 15 P00846,Q9Y487 2 +Cysteine protease 0.4469386861570177 1.614625885560885 0.1063917362587965 1.0 0.2195385033911673 45 O60343,Q66K14,Q06210,Q92820,Q8NHP8,Q96FW1,Q0IIM8,P17812,Q8TC07,Q06203,P07858,Q9Y4E8,Q9BXI6,Q96K76,Q13510,P42574,Q9NRF8 17 +Damaged DNA-binding protein 0.7752302173721781 1.608534075503074 0.1077182594212597 1.0 0.2207882957002311 5 Q9NQE9 1 +SNARE protein 0.6317036514794312 1.567564144998732 0.1169828853137966 1.0 0.2335167000505729 10 O43752,O95721,Q9P2W9 3 +Calmodulin 0.5487985940879692 1.5391673855641248 0.1237634375657337 1.0 0.2417163851049071 16 Q02818,P80303 2 +Intracellular calcium-sensing protein 0.5487985940879692 1.5391673855641248 0.1237634375657337 1.0 0.2417163851049071 16 Q02818,P80303 2 +Aspartic protease 0.8080935273824473 1.3775084236966062 0.1683551122246607 1.0 0.2950279396467483 4 Q5BJF2 1 +Membrane trafficking regulatory protein 0.4672278912344547 1.2798340247690825 0.2006035147453386 1.0 0.3328625118531449 23 O43731 1 +BUB family 0.8325819056206792 1.2665874329268605 0.2053028483290615 1.0 0.3371009353847653 2 O60566 1 +Phospholipase 0.7789825321320125 1.2649188575690695 0.2059004166769398 1.0 0.3372726476704032 4 Q8NCC3 1 +Transporter 0.4348834286571392 1.2648338467945877 0.205930895452602 1.0 0.3372726476704032 183 Q9UBX3,Q99523,P12235,O43731,Q9Y487,Q9P253,P00846,Q70HW3,Q92973,P24390,P53985,Q93050,P17900,Q9HD45,Q9Y619,O43772,Q6NT16,P41440,Q6NUK4,O43752,O95721,Q9BSK2,Q8IXU6,Q9H2D1,Q15070,Q9BVK6,P49257,Q9HC07,O95563,Q9P2W9,Q96QD8,Q02978,Q03518,Q15363,Q9Y6C9,Q99805 36 +Phosphatase inhibitor 0.653459980764736 1.2158811776527645 0.2240301891957239 1.0 0.3578976908810336 6 Q01105,Q99733 2 +Serine protease 0.438992887893727 1.184809733418502 0.2360926832976926 1.0 0.3722485978243502 28 Q92945,Q9HB40,P67812,P42785,Q96AE4,Q9H3G5,P10619,P48147,Q8N2K0 9 +Mitochondrial di- and tri-carboxylic acid transporter subfamily 0.8308604024823979 1.1311372116712357 0.2579973442047523 1.0 0.3934015846009361 3 Q02978 1 +Oxidase 0.4571098941147219 1.123673844896142 0.2611514161105082 1.0 0.3970723285890767 19 Q15800,Q15067,P14406,O75880,O43169 5 +Lysine-specific demethylase 0.7914036669672222 1.0995634995010464 0.2715223527207344 1.0 0.4077736416311391 2 Q8NB78 1 +Translation initiation factor 0.4371924050818159 1.048714448762062 0.2943095622179688 1.0 0.4267405437006243 22 P06730,O75153 2 +PI3/PI4 kinase family 0.7227854513729957 1.048496438327563 0.2944099424088442 1.0 0.4267405437006243 4 P42356 1 +G-protein 0.4060857927718148 1.0156915364753991 0.3097762996025044 1.0 0.4401193327685854 34 O95373,Q9NTK5,Q5TAQ9,P11233,O60313 5 +V-type ATPase 0.5716902267620914 1.0056399829041358 0.3145887832682725 1.0 0.4445276285312546 7 Q9Y487 1 +Phosphatase modulator 0.5372689928526733 0.9933508658930152 0.3205389971424877 1.0 0.4507918283004559 8 Q01105,Q99733 2 +Protease inhibitor 0.5162135848135673 0.9871134756204968 0.3235870122952238 1.0 0.4529347143836241 10 P30086,P11047 2 +Miscellaneous SLC25 mitochondrial transporters 0.7451157198677314 0.9158663739860914 0.3597369853735199 1.0 0.4845479253105776 2 Q9Y6C9 1 +Translation factor 0.3975030254728471 0.8654938493303019 0.3867677903655648 1.0 0.5056423657827623 27 P06730,O75153 2 +Phosphatase 0.3789026356135806 0.7965442596365315 0.4257157609393303 1.0 0.5376373908644851 34 P30154,Q9NPH0,P30153,O95140 4 +Isomerase 0.3823828671328454 0.7253068531718442 0.4682638023743721 1.0 0.5709195245830563 25 P62942,Q15125,Q02790 3 +Lipid kinase 0.5003939391169363 0.6891708822149087 0.4907157382200724 1.0 0.5889721497390367 7 P42356,Q9UBF8 2 +mRNA splicing factor 0.3338684485876845 0.6739214793165929 0.5003612355505251 1.0 0.5950551000257818 63 Q93062,Q92804,Q9BWF3,O75525,O95391,Q01844,Q13242,Q14011,P62995,P38159,P62312,P98179,Q8IY67,Q96PK6,Q15428,P35637 16 +ABCB subfamily 0.6980078184608244 0.6605315238312908 0.5089127956639072 1.0 0.6014423948755268 3 Q03518 1 +Growth factor 0.5355652874138279 0.6341642435732159 0.5259736400292434 1.0 0.6118709011525874 5 Q96PC5,P51858 2 +Small GTPase 0.3720109717097137 0.6323619679301354 0.5271503796703683 1.0 0.6122126129058436 24 O95373,P11233,O60313 3 +ATP-binding cassette transporter family 0.5347320263376567 0.630981527554579 0.5280526027815833 1.0 0.6125763601704926 5 Q03518 1 +PAKA subfamily 0.6471295461376438 0.5565261738035718 0.5778512067233925 1.0 0.645066218161739 2 Q13177 1 +Protein arginine methyltransferase 0.5645112781954916 0.4799694672134739 0.6312491039891284 1.0 0.6775016183165051 4 Q99873,Q86X55,O14744 3 +Hydrolase 0.321407743318563 0.3978372402424388 0.6907501644519698 1.0 0.7216274947564526 105 P50897,Q969T7,Q9NRW3,P30154,Q9NPH0,Q9UMR5,Q9H0P0,P30153,Q8NCC3,O95140 10 +Oxygenase 0.4590659536552663 0.3617036683604345 0.7175734854614664 1.0 0.739619846263553 5 Q16850 1 +Acetyltransferase 0.326949098420043 0.297625629960306 0.765988910715077 1.0 0.7860172344782241 21 Q9BWD1 1 +AMPK subfamily 0.5524496543432542 0.2824189545982453 0.7776222826380255 1.0 0.7975613155261799 2 P54646 1 +Zinc finger transcription factor 0.415889256695762 0.2769171385260959 0.7818437323778431 1.0 0.8007065304509668 6 Q8WU90,P49711,Q7Z3K3,O95785,P41223 5 +Ion channel 0.3954638446746382 0.2698922452351399 0.7872431532789248 1.0 0.8054430687752896 7 Q96S66,P0CG08 2 +Protein phosphatase 0.3406913390292043 0.262672470355481 0.7928030373346331 1.0 0.8107327028790742 14 P30154 1 +SRPK family 0.5407273820258516 0.255661248391542 0.7982124201778995 1.0 0.8150622650810168 2 P78362 1 +Hsp90 family chaperone 0.4769924812030113 0.2356555207535914 0.8136999871484265 1.0 0.8300617818875563 4 P08238,P14625,P07900 3 +Oxidoreductase 0.3122566437800676 0.1800939194209926 0.857078836162315 1.0 0.8721741581299487 119 Q8N4Q0,Q15392,Q96CU9,Q15067,O75438,O95168,Q14739,Q9BY49,P00374,Q15800,Q9UDW1,O95881,P14406,Q7LG56,O43169,O75880,Q16850,Q9NZ01,P20674,O95831,Q9UBM7,O75306,Q8N0U8 23 +Chromodomain 0.5132291040288572 0.1755625515122462 0.8606376248785399 1.0 0.8745120956264597 3 Q13185,P45973 2 +Lysine demethylase 0.50926428905921 0.168856920584684 0.8659091849270903 1.0 0.879439015941576 3 Q8NB78 1 +Transcription cofactor 0.314968522567135 0.1505320863535723 0.8803448378938965 1.0 0.8936638666760881 15 O00625 1 +Peroxidase 0.4301322558726993 0.1404265663657539 0.8883229688911054 1.0 0.9008833619178446 4 P30048 1 +C2H2 zinc finger transcription factor 0.4156390977443649 0.1166971116169724 0.9071000792334716 1.0 0.9185823587174397 4 P49711,Q7Z3K3,O95785 3 +KRAB box transcription factor 0.4156390977443649 0.1166971116169724 0.9071000792334716 1.0 0.9185823587174397 4 P49711,Q7Z3K3,O95785 3 +CDK family 0.3636158632497551 0.1100479735623851 0.9123713285299582 1.0 0.923470736419617 5 Q00535 1 +Glucosidase 0.4283137962127976 0.0902212948187578 0.9281113625161486 1.0 0.9384888838277048 2 P10253 1 +Carbohydrate kinase 0.3931469792605887 0.0683746737709421 0.9454873820409304 1.0 0.9551305267824844 2 P19367 1 +mRNA processing factor 0.2707480912096878 0.0674591779904829 0.9462161592060458 1.0 0.9554027238585316 78 Q93062,Q92804,Q9BWF3,O75525,O95391,Q01844,Q13242,Q14011,P62995,P38159,P98179,Q8IY67,Q15428,Q96PK6,P62312,P35637 16 +P-type ATPases 0.3164861612515046 0.0352100766935328 0.9719122271751468 1.0 0.9794976640739812 5 P20020,P16615,P05026,P05023 4 +MAPK family 0.361329264957037 0.0351463194130999 0.9719630666580276 1.0 0.9794976640739812 3 P28482 1 +IKK family 0.3427540589296468 0.0304215097501739 0.9757308904934876 1.0 0.9828185240806072 3 O15111,O14920 2 +Nucleotide phosphatase 0.3008607804832552 0.0261709255060334 0.9791210060215256 1.0 0.985332407323642 8 O95140,Q5TFE4 2 +Na+/K+-ATPases 0.3162958508719237 0.0261043846911791 0.9791740797778694 1.0 0.985332407323642 3 P05026,P05023 2 diff --git a/pharos_dto/selections.json b/pharos_dto/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..71c1ab2651217dee243c2e807e68950cf448a018 --- /dev/null +++ b/pharos_dto/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase", "1,4-alpha-glucan-branching enzyme", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "10 kDa heat shock protein, mitochondrial", "116 kDa U5 small nuclear ribonucleoprotein component", "14-3-3 protein beta/alpha", "14-3-3 protein epsilon", "14-3-3 protein eta", "14-3-3 protein gamma", "14-3-3 protein theta", "14-3-3 protein zeta/delta", "2',3'-cyclic-nucleotide 3'-phosphodiesterase", "2',5'-phosphodiesterase 12", "2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial", "2-hydroxyacyl-CoA lyase 1", "26S proteasome non-ATPase regulatory subunit 1", "26S proteasome non-ATPase regulatory subunit 12", "26S proteasome non-ATPase regulatory subunit 13", "26S proteasome non-ATPase regulatory subunit 14", "26S proteasome non-ATPase regulatory subunit 2", "26S proteasome non-ATPase regulatory subunit 3", "26S proteasome non-ATPase regulatory subunit 4", "26S proteasome non-ATPase regulatory subunit 7", "26S proteasome non-ATPase regulatory subunit 8", "26S proteasome regulatory subunit 10B", "26S proteasome regulatory subunit 4", "26S proteasome regulatory subunit 6A", "26S proteasome regulatory subunit 6B", "26S proteasome regulatory subunit 7", "26S proteasome regulatory subunit 8", "28S ribosomal protein S11, mitochondrial", "28S ribosomal protein S16, mitochondrial", "28S ribosomal protein S2, mitochondrial", "28S ribosomal protein S27, mitochondrial", "28S ribosomal protein S29, mitochondrial", "28S ribosomal protein S35, mitochondrial", "28S ribosomal protein S5, mitochondrial", "28S ribosomal protein S7, mitochondrial", "3'(2'),5'-bisphosphate nucleotidase 1", "3'-5' exoribonuclease 1", "3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase", "3-hydroxyacyl-CoA dehydrogenase type-2", "3-hydroxyisobutyrate dehydrogenase, mitochondrial", "3-hydroxyisobutyryl-CoA hydrolase, mitochondrial", "3-ketoacyl-CoA thiolase, mitochondrial", "3-ketoacyl-CoA thiolase, peroxisomal", "3-mercaptopyruvate sulfurtransferase", "39S ribosomal protein L1, mitochondrial", "39S ribosomal protein L11, mitochondrial", "39S ribosomal protein L12, mitochondrial", "39S ribosomal protein L14, mitochondrial", "39S ribosomal protein L16, mitochondrial", "39S ribosomal protein L17, mitochondrial", "39S ribosomal protein L19, mitochondrial", "39S ribosomal protein L2, mitochondrial", "39S ribosomal protein L21, mitochondrial", "39S ribosomal protein L22, mitochondrial", "39S ribosomal protein L23, mitochondrial", "39S ribosomal protein L39, mitochondrial", "39S ribosomal protein L43, mitochondrial", "39S ribosomal protein L44, mitochondrial", "39S ribosomal protein L47, mitochondrial", "39S ribosomal protein L9, mitochondrial", "39S ribosomal protein S18a, mitochondrial", "4-trimethylaminobutyraldehyde dehydrogenase", "40S ribosomal protein S10", "40S ribosomal protein S11", "40S ribosomal protein S12", "40S ribosomal protein S13", "40S ribosomal protein S14", "40S ribosomal protein S15", "40S ribosomal protein S15a", "40S ribosomal protein S17", "40S ribosomal protein S18", "40S ribosomal protein S19", "40S ribosomal protein S2", "40S ribosomal protein S20", "40S ribosomal protein S21", "40S ribosomal protein S23", "40S ribosomal protein S24", "40S ribosomal protein S26", "40S ribosomal protein S28", "40S ribosomal protein S3", "40S ribosomal protein S3a", "40S ribosomal protein S4, X isoform", "40S ribosomal protein S5", "40S ribosomal protein S6", "40S ribosomal protein S7", "40S ribosomal protein S8", "40S ribosomal protein S9", "40S ribosomal protein SA", "45 kDa calcium-binding protein", "4F2 cell-surface antigen heavy chain", "5'-AMP-activated protein kinase catalytic subunit alpha-1", "5'-AMP-activated protein kinase catalytic subunit alpha-2", "5'-AMP-activated protein kinase subunit gamma-1", "5'-nucleotidase domain-containing protein 1", "5'-nucleotidase domain-containing protein 2", "5-formyltetrahydrofolate cyclo-ligase", "55 kDa erythrocyte membrane protein", "6-phosphogluconate dehydrogenase, decarboxylating", "6-phosphogluconolactonase", "60 kDa SS-A/Ro ribonucleoprotein", "60S ribosomal protein L10", "60S ribosomal protein L10a", "60S ribosomal protein L11", "60S ribosomal protein L12", "60S ribosomal protein L13", "60S ribosomal protein L13a", "60S ribosomal protein L14", "60S ribosomal protein L15", "60S ribosomal protein L18", "60S ribosomal protein L19", "60S ribosomal protein L21", "60S ribosomal protein L22", "60S ribosomal protein L23", "60S ribosomal protein L23a", "60S ribosomal protein L24", "60S ribosomal protein L26", "60S ribosomal protein L27", "60S ribosomal protein L27a", "60S ribosomal protein L28", "60S ribosomal protein L29", "60S ribosomal protein L3", "60S ribosomal protein L30", "60S ribosomal protein L31", "60S ribosomal protein L32", "60S ribosomal protein L35", "60S ribosomal protein L35a", "60S ribosomal protein L36", "60S ribosomal protein L36a", "60S ribosomal protein L37", "60S ribosomal protein L38", "60S ribosomal protein L5", "60S ribosomal protein L6", "60S ribosomal protein L7", "60S ribosomal protein L7-like 1", "60S ribosomal protein L7a", "60S ribosomal protein L8", "60S ribosomal protein L9", "7,8-dihydro-8-oxoguanine triphosphatase", "7-dehydrocholesterol reductase", "7-methylguanosine phosphate-specific 5'-nucleotidase", "A-kinase anchor protein 1, mitochondrial", "ABCB subfamily", "ABCC subfamily", "ABCD subfamily of peroxisomal ABC transporters", "ADP-dependent glucokinase", "ADP-ribose pyrophosphatase, mitochondrial", "ADP-sugar pyrophosphatase", "ADP/ATP translocase 1", "ADP/ATP translocase 2", "ADP/ATP translocase 3", "AFG3-like protein 2", "AGC group", "AH receptor-interacting protein", "AK1 subfamily", "AK2 subfamily", "AK3 subfamily", "AKT family", "AMPK subfamily", "AP-1 complex subunit beta-1", "AP-1 complex subunit gamma-1", "AP-1 complex subunit mu-1", "AP-2 complex subunit alpha-1", "AP-2 complex subunit alpha-2", "AP-2 complex subunit beta", "AP-2 complex subunit mu", "AP-2 complex subunit sigma", "AP-3 complex subunit beta-1", "AP-3 complex subunit delta-1", "AP-3 complex subunit mu-1", "AT-rich interactive domain-containing protein 3B", "ATP synthase F(0) complex subunit B1, mitochondrial", "ATP synthase mitochondrial F1 complex assembly factor 1", "ATP synthase subunit a", "ATP synthase subunit alpha, mitochondrial", "ATP synthase subunit beta, mitochondrial", "ATP synthase subunit d, mitochondrial", "ATP synthase subunit e, mitochondrial", "ATP synthase subunit f, mitochondrial", "ATP synthase subunit gamma, mitochondrial", "ATP-binding cassette sub-family B member 7, mitochondrial", "ATP-binding cassette sub-family D member 3", "ATP-binding cassette sub-family F member 1", "ATP-binding cassette sub-family F member 2", "ATP-binding cassette sub-family F member 3", "ATP-binding cassette transporter family", "ATP-citrate synthase", "ATP-dependent 6-phosphofructokinase, muscle type", "ATP-dependent 6-phosphofructokinase, platelet type", "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial", "ATP-dependent DNA helicase Q1", "ATP-dependent DNA helicase Q4", "ATP-dependent DNA helicase Q5", "ATP-dependent PFK group I subfamily", "ATP-dependent RNA helicase A", "ATP-dependent RNA helicase DHX29", "ATP-dependent RNA helicase DHX8", "ATP-dependent zinc metalloprotease YME1L1", "ATPase ASNA1", "ATPase family AAA domain-containing protein 2", "ATPase family AAA domain-containing protein 3A", "ATPase family AAA domain-containing protein 3B", "ATPase inhibitor, mitochondrial", "Acetoacetyl-CoA synthetase", "Acetolactate synthase-like protein", "Acetyl-CoA acetyltransferase, cytosolic", "Acetyl-CoA acetyltransferase, mitochondrial", "Acetyltransferase", "Acid ceramidase", "Acidic leucine-rich nuclear phosphoprotein 32 family member B", "Acidic leucine-rich nuclear phosphoprotein 32 family member E", "Aconitate hydratase, mitochondrial", "Actin and actin related protein", "Actin binding motor protein", "Actin family cytoskeletal protein", "Actin-like protein 6A", "Actin-related protein 10", "Actin-related protein 2", "Actin-related protein 2/3 complex subunit 1A", "Actin-related protein 2/3 complex subunit 1B", "Actin-related protein 2/3 complex subunit 3", "Actin-related protein 2/3 complex subunit 4", "Actin-related protein 3", "Actin-related protein 6", "Acyl-CoA dehydrogenase family member 11", "Acyl-CoA dehydrogenase family member 9, mitochondrial", "Acyl-CoA synthetase family member 3, mitochondrial", "Acyl-CoA-binding domain-containing protein 5", "Acyl-coenzyme A thioesterase 8", "Acyl-coenzyme A thioesterase 9, mitochondrial", "Acylamino-acid-releasing enzyme", "Acylpyruvase FAHD1, mitochondrial", "Acyltransferase", "Adenosine 3'-phospho 5'-phosphosulfate transporter 1", "Adenosine deaminase", "Adenosine kinase", "Adenosylhomocysteinase", "Adenylate kinase 2, mitochondrial", "Adenylate kinase 4, mitochondrial", "Adenylate kinase family", "Adenylate kinase isoenzyme 1", "Adenylate kinase isoenzyme 6", "Adenylosuccinate lyase", "Adenylosuccinate synthetase isozyme 2", "Adenylyl cyclase-associated protein 1", "Adenylyl cyclase-associated protein 2", "Afadin", "Alanine aminotransferase 2", "Alanine--tRNA ligase, cytoplasmic", "Alanine--tRNA ligase, mitochondrial", "Alanine/serine/cysteine transporter subfamily", "Alanyl-tRNA editing protein Aarsd1", "Alcohol dehydrogenase [NADP(+)]", "Alcohol dehydrogenase class-3", "Aldehyde dehydrogenase X, mitochondrial", "Aldehyde dehydrogenase, mitochondrial", "Aldose 1-epimerase", "Aldose reductase", "Alpha-adducin", "Alpha-aminoadipic semialdehyde dehydrogenase", "Alpha-centractin", "Alpha-enolase", "Alpha-globin transcription factor CP2", "Alpha-soluble NSF attachment protein", "Alpha-taxilin", "Amidophosphoribosyltransferase", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 1", "Aminoacyl-tRNA synthetase", "Amylase", "Anaphase-promoting complex subunit 1", "Ancient ubiquitous protein 1", "Anion channel tweety (tweety) family", "Ankyrin repeat and SOCS box protein 6", "Annexin", "Antibacterial response protein", "Antigen peptide transporter 1", "Ap2-associated protein kinase 1", "Apoptosis regulator BAX", "Apoptosis-inducing factor 1, mitochondrial", "Arfaptin-1", "Arfaptin-2", "Armadillo repeat protein deleted in velo-cardio-facial syndrome", "Asparagine synthetase [glutamine-hydrolyzing]", "Asparagine--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, mitochondrial", "Aspartic protease", "Ataxin-2", "Ataxin-2-like protein", "Atlastin-2", "Atlastin-3", "Atp-dependent 6-phosphofructokinase, liver type", "Atypical group", "B-cell receptor-associated protein 31", "BTB/POZ domain-containing protein KCTD12", "BUB family", "Basic leucine zipper and W2 domain-containing protein 1", "Basic leucine zipper and W2 domain-containing protein 2", "Bcl-2-associated transcription factor 1", "Beta-1,4-galactosyltransferase 1", "Beta-galactosidase", "Beta-hexosaminidase subunit alpha", "Beta-hexosaminidase subunit beta", "Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1", "Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase", "Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6", "Bifunctional coenzyme A synthase", "Bifunctional epoxide hydrolase 2", "Bifunctional glutamate/proline--tRNA ligase", "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial", "Bifunctional purine biosynthesis protein PURH", "Biliverdin reductase A", "Biogenesis of lysosome-related organelles complex 1 subunit 1", "Bleomycin hydrolase", "Brain-specific angiogenesis inhibitor 1-associated protein 2", "Branched-chain-amino-acid aminotransferase, mitochondrial", "Breast cancer type 1 susceptibility protein", "Bromodomain", "Bromodomain-containing protein 2", "Bromodomain-containing protein 4", "C-1-tetrahydrofolate synthase, cytoplasmic", "C-Jun-amino-terminal kinase-interacting protein 4", "C-terminal-binding protein 1", "C-terminal-binding protein 2", "C2H2 zinc finger transcription factor", "CAAX prenyl protease 1 homolog", "CAD protein", "CAMK group", "CAMK1 family", "CAMK2 family", "CAMKL family", "CASK family", "CCAAT/enhancer-binding protein zeta", "CCK4 family", "CCR4-NOT transcription complex subunit 1", "CCR4-NOT transcription complex subunit 3", "CCR4-NOT transcription complex subunit 7", "CD166 antigen", "CD2 antigen cytoplasmic tail-binding protein 2", "CDK family", "CDK1 subfamily", "CDK4 subfamily", "CDK5 subfamily", "CDKN2A-interacting protein", "CHK1 subfamily", "CK1 family", "CK1 group", "CK2 family", "CLIP-associating protein 1", "CLIP-associating protein 2", "CMGC group", "COP9 signalosome complex subunit 3", "COP9 signalosome complex subunit 5", "COP9 signalosome complex subunit 6", "COP9 signalosome complex subunit 8", "CSK family", "CTP synthase 1", "CTP synthase 2", "Ca2+-ATPases", "Cadherin", "Calcium homeostasis endoplasmic reticulum protein", "Calcium uniporter protein, mitochondrial", "Calcium uptake protein 1, mitochondrial", "Calcium uptake protein 2, mitochondrial", "Calcium-binding mitochondrial carrier protein Aralar1", "Calcium-binding mitochondrial carrier protein Aralar2", "Calcium-binding mitochondrial carrier protein SCaMC-1", "Calcium-binding protein", "Calcium-binding protein 39", "Calcium-regulated heat-stable protein 1", "Calcium/calmodulin-dependent protein kinase type 1", "Calcium/calmodulin-dependent protein kinase type ii subunit gamma", "Calcyclin-binding protein", "Calmegin", "Calmodulin", "Calmodulin-3", "Calnexin", "Calpain-1 catalytic subunit", "Calpain-2 catalytic subunit", "Calponin-2", "Calponin-3", "Calreticulin", "Calumenin", "Camp-dependent protein kinase catalytic subunit alpha", "Cancer-related nucleoside-triphosphatase", "Caprin-1", "Carbohydrate kinase", "Carbohydrate sulfotransferase 14", "Carnitine O-palmitoyltransferase 1, liver isoform", "Carnitine O-palmitoyltransferase 2, mitochondrial", "Cartilage-associated protein", "Casein kinase II subunit alpha'", "Casein kinase i isoform alpha", "Casein kinase ii subunit beta", "Caspase-2", "Caspase-3", "Cat eye syndrome critical region protein 2", "Catechol O-methyltransferase", "Catechol O-methyltransferase domain-containing protein 1", "Catenin alpha-1", "Catenin delta-1", "Cathepsin B", "Cation-dependent mannose-6-phosphate receptor", "Cation-independent mannose-6-phosphate receptor", "Cell adhesion", "Cell cycle and apoptosis regulator protein 2", "Cell division control protein 42 homolog", "Cell division control protein 45 homolog", "Cell division cycle and apoptosis regulator protein 1", "Cell-cell junction", "Cellular structure", "Cellular tumor antigen p53", "Centrin-2", "Centromere-associated protein E", "Centromere/kinetochore protein zw10 homolog", "Centrosomal protein of 170 kDa", "Centrosome-associated protein CEP250", "Ceramide glucosyltransferase", "Chaperone", "Chaperonin", "Charged multivesicular body protein 3", "Charged multivesicular body protein 4a", "Charged multivesicular body protein 4b", "Charged multivesicular body protein 5", "Charged multivesicular body protein 7", "Chitobiosyldiphosphodolichol beta-mannosyltransferase", "Chloride channel CLIC-like protein 1", "Chloride channel family", "Chloride intracellular channel protein 1", "Chloride intracellular channel protein 4", "Choline kinase alpha", "Choline/ethanolamine kinase family", "Chromatin accessibility complex protein 1", "Chromatin assembly factor 1 subunit A", "Chromatin assembly factor 1 subunit B", "Chromatin target of PRMT1 protein", "Chromatin/chromatin-binding protein", "Chromobox protein homolog 1", "Chromobox protein homolog 3", "Chromobox protein homolog 5", "Chromodomain", "Chromosome-associated kinesin KIF4A", "Cilia- and flagella-associated protein 20", "Citrate synthase, mitochondrial", "ClC-3/CLCN3 subfamily", "Clathrin heavy chain 1", "Clathrin light chain A", "Cleavage and polyadenylation specificity factor subunit 1", "Cleavage and polyadenylation specificity factor subunit 3", "Cleavage and polyadenylation specificity factor subunit 5", "Cleavage and polyadenylation specificity factor subunit 6", "Cleavage and polyadenylation specificity factor subunit 7", "Cleavage stimulation factor subunit 2", "Cleavage stimulation factor subunit 3", "Cleft lip and palate transmembrane protein 1", "Cleft lip and palate transmembrane protein 1-like protein", "Clustered mitochondria protein homolog", "Coactosin-like protein", "Coatomer subunit alpha", "Coatomer subunit beta", "Coatomer subunit beta'", "Coatomer subunit delta", "Coatomer subunit epsilon", "Coatomer subunit gamma-1", "Coatomer subunit gamma-2", "Coatomer subunit zeta-1", "Cohesin subunit SA-1", "Cohesin subunit SA-2", "Coilin", "Cold-inducible RNA-binding protein", "Collectin-12", "Condensin complex subunit 1", "Core histone macro-H2A.1", "Core histone macro-H2A.2", "Coronin-1B", "Coronin-1C", "Creatine kinase B-type", "Creatine kinase U-type, mitochondrial", "Crooked neck-like protein 1", "Cullin-1", "Cullin-2", "Cullin-4B", "Cullin-5", "Cullin-associated NEDD8-dissociated protein 1", "Cullin-associated NEDD8-dissociated protein 2", "Cyclase", "Cyclin-A2", "Cyclin-dependent kinase 1", "Cyclin-dependent kinase 11b", "Cyclin-dependent kinase 4", "Cyclin-dependent kinase 6", "Cyclin-dependent-like kinase 5", "Cyclin-g-associated kinase", "Cystathionine gamma-lyase", "Cystatin-B", "Cysteine and glycine-rich protein 2", "Cysteine and histidine-rich domain-containing protein 1", "Cysteine desulfurase, mitochondrial", "Cysteine protease", "Cysteine protease ATG4B", "Cysteine protease inhibitor", "Cysteine--tRNA ligase, cytoplasmic", "Cytochrome b-c1 complex subunit 1, mitochondrial", "Cytochrome b-c1 complex subunit 2, mitochondrial", "Cytochrome b-c1 complex subunit 7", "Cytochrome b-c1 complex subunit 9", "Cytochrome b5 type B", "Cytochrome c oxidase subunit 2", "Cytochrome c oxidase subunit 5A, mitochondrial", "Cytochrome c oxidase subunit 5B, mitochondrial", "Cytochrome c oxidase subunit 7A-related protein, mitochondrial", "Cytochrome c oxidase subunit 7A2, mitochondrial", "Cytochrome c oxidase subunit 7C, mitochondrial", "Cytochrome c oxidase subunit NDUFA4", "Cytochrome c-type heme lyase", "Cytokine", "Cytokine receptor", "Cytoplasmic FMR1-interacting protein 1", "Cytoplasmic FMR1-interacting protein 2", "Cytoplasmic aconitate hydratase", "Cytoplasmic dynein 1 heavy chain 1", "Cytoplasmic dynein 1 intermediate chain 2", "Cytoplasmic dynein 1 light intermediate chain 1", "Cytoplasmic dynein 1 light intermediate chain 2", "Cytoplasmic dynein 2 heavy chain 1", "Cytoskeleton-associated protein 5", "Cytosol aminopeptidase", "Cytosolic 5'-nucleotidase 3A", "Cytosolic acyl coenzyme A thioester hydrolase", "Cytosolic non-specific dipeptidase", "Cytosolic purine 5'-nucleotidase", "D-3-phosphoglycerate dehydrogenase", "D-dopachrome decarboxylase", "DDB1- and CUL4-associated factor 8", "DMPK family", "DNA (cytosine-5)-methyltransferase 1", "DNA binding protein", "DNA dC->dU-editing enzyme APOBEC-3C", "DNA damage-binding protein 1", "DNA glycosylase", "DNA helicase", "DNA ligase", "DNA ligase 1", "DNA ligase 3", "DNA methyltransferase", "DNA mismatch repair protein Msh2", "DNA mismatch repair protein Msh3", "DNA mismatch repair protein Msh6", "DNA polymerase alpha subunit B", "DNA polymerase delta subunit 2", "DNA polymerase epsilon subunit 2", "DNA polymerase epsilon subunit 4", "DNA polymerase processivity factor", "DNA primase small subunit", "DNA replication licensing factor MCM2", "DNA replication licensing factor MCM3", "DNA replication licensing factor MCM4", "DNA replication licensing factor MCM5", "DNA replication licensing factor MCM6", "DNA replication licensing factor MCM7", "DNA topoisomerase", "DNA topoisomerase 1", "DNA-3-methyladenine glycosylase", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "DNA-directed RNA polymerase I subunit RPA1", "DNA-directed RNA polymerase I subunit RPA2", "DNA-directed RNA polymerase I subunit RPA43", "DNA-directed RNA polymerase II subunit RPB1", "DNA-directed RNA polymerase II subunit RPB2", "DNA-directed RNA polymerase II subunit RPB3", "DNA-directed RNA polymerase II subunit RPB4", "DNA-directed RNA polymerase II subunit RPB7", "DNA-directed RNA polymerase III subunit RPC1", "DNA-directed RNA polymerase III subunit RPC3", "DNA-directed RNA polymerase, mitochondrial", "DNA-directed RNA polymerases I and III subunit RPAC1", "DNA-directed RNA polymerases I, II, and III subunit RPABC1", "DNA-directed RNA polymerases I, II, and III subunit RPABC5", "DNAPK subfamily", "DYRK family", "Damaged DNA-binding protein", "Deacetylase", "Deaminase", "Death-inducer obliterator 1", "Decarboxylase", "Dedicator of cytokinesis protein 7", "Dehydratase", "Dehydrogenase", "Delta(24)-sterol reductase", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial", "Delta-1-pyrroline-5-carboxylate synthase", "Density-regulated protein", "Deoxycytidylate deaminase", "Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial", "Derlin-1", "Desmocollin-3", "Desmoglein-2", "Desmoplakin", "Digestive organ expansion factor homolog", "Dihydrofolate reductase", "Dihydrolipoyl dehydrogenase, mitochondrial", "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial", "Dihydroorotate dehydrogenase (quinone), mitochondrial", "Dihydropteridine reductase", "Dihydropyrimidinase-related protein 2", "Dihydropyrimidinase-related protein 3", "Dihydropyrimidinase-related protein 5", "Dipeptidyl peptidase 1", "Dipeptidyl peptidase 3", "Dipeptidyl peptidase 9", "Diphthine methyl ester synthase", "Dna-dependent protein kinase catalytic subunit", "Dolichol-phosphate mannosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B", "Dolichyldiphosphatase 1", "Double-stranded RNA-specific adenosine deaminase", "Drebrin", "Drebrin-like protein", "Dual specificity mitogen-activated protein kinase kinase 1", "Dual specificity mitogen-activated protein kinase kinase 3", "Dual specificity protein kinase ttk", "Dynactin subunit 1", "Dynactin subunit 2", "Dynamin-1-like protein", "Dynamin-2", "Dynamin-like 120 kDa protein, mitochondrial", "Dynein light chain 1, cytoplasmic", "Dynein light chain 2, cytoplasmic", "Dystonin", "E3 SUMO-protein ligase RanBP2", "E3 ubiquitin-protein ligase ARIH1", "E3 ubiquitin-protein ligase ARIH2", "E3 ubiquitin-protein ligase CBL", "E3 ubiquitin-protein ligase HUWE1", "E3 ubiquitin-protein ligase Itchy homolog", "E3 ubiquitin-protein ligase MARCH5", "E3 ubiquitin-protein ligase RBBP6", "E3 ubiquitin-protein ligase RNF14", "E3 ubiquitin-protein ligase ZNF598", "E3 ubiquitin-protein ligase listerin", "EGFR family", "EH domain-containing protein 1", "EH domain-containing protein 4", "ELKS/Rab6-interacting/CAST family member 1", "ER lumen protein-retaining receptor 1", "ER lumen protein-retaining receptor 3", "ER membrane protein complex subunit 2", "ERK subfamily", "ERO1-like protein alpha", "Early endosome antigen 1", "Electron transfer flavoprotein subunit alpha, mitochondrial", "Electron transfer flavoprotein subunit beta", "Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial", "Elongation factor 1-alpha 2", "Elongation factor 1-beta", "Elongation factor 1-delta", "Elongation factor 2", "Elongation factor Ts, mitochondrial", "Elongation factor Tu, mitochondrial", "Elongation factor-like GTPase 1", "Elongator complex protein 1", "Elongin-B", "Elongin-C", "Endodeoxyribonuclease", "Endoplasmic reticulum aminopeptidase 1", "Endoplasmic reticulum metallopeptidase 1", "Endoplasmic reticulum protein SC65", "Endoplasmic reticulum resident protein 29", "Endoplasmin", "Endoribonuclease", "Endoribonuclease Dicer", "Endothelin-converting enzyme 1", "Enhancer of mRNA-decapping protein 4", "Enhancer of rudimentary homolog", "Enoyl-CoA delta isomerase 1, mitochondrial", "Enoyl-CoA delta isomerase 2, mitochondrial", "Enoyl-CoA hydratase, mitochondrial", "Enzyme", "Enzyme modulator", "Epidermal growth factor receptor", "Epidermal growth factor receptor substrate 15", "Epidermal growth factor receptor substrate 15-like 1", "Epigenetic regulator", "Epimerase/racemase", "Epiplakin", "Eraser", "Erythrocyte band 7 integral membrane protein", "Esterase", "Ethylmalonyl-CoA decarboxylase", "Eukaryotic peptide chain release factor GTP-binding subunit ERF3A", "Eukaryotic peptide chain release factor subunit 1", "Eukaryotic translation initiation factor 2 subunit 1", "Eukaryotic translation initiation factor 2 subunit 2", "Eukaryotic translation initiation factor 2A", "Eukaryotic translation initiation factor 3 subunit A", "Eukaryotic translation initiation factor 3 subunit B", "Eukaryotic translation initiation factor 3 subunit D", "Eukaryotic translation initiation factor 3 subunit E", "Eukaryotic translation initiation factor 3 subunit F", "Eukaryotic translation initiation factor 3 subunit H", "Eukaryotic translation initiation factor 3 subunit I", "Eukaryotic translation initiation factor 3 subunit J", "Eukaryotic translation initiation factor 3 subunit L", "Eukaryotic translation initiation factor 4 gamma 1", "Eukaryotic translation initiation factor 4 gamma 2", "Eukaryotic translation initiation factor 4 gamma 3", "Eukaryotic translation initiation factor 4B", "Eukaryotic translation initiation factor 4E", "Eukaryotic translation initiation factor 4E type 2", "Eukaryotic translation initiation factor 4H", "Eukaryotic translation initiation factor 5", "Eukaryotic translation initiation factor 5A-1", "Eukaryotic translation initiation factor 5B", "Eukaryotic translation initiation factor 6", "Exocyst complex component 1", "Exocyst complex component 3", "Exocyst complex component 4", "Exocyst complex component 5", "Exocyst complex component 6B", "Exocyst complex component 7", "Exodeoxyribonuclease", "Exonuclease 1", "Exoribonuclease", "Exosome complex component CSL4", "Exosome complex component MTR3", "Exosome complex component RRP4", "Exosome complex component RRP40", "Exosome complex component RRP42", "Exosome complex component RRP43", "Exosome complex component RRP45", "Exosome complex component RRP46", "Exosome complex exonuclease RRP44", "Exportin-1", "Exportin-2", "Exportin-4", "Exportin-5", "Exportin-7", "Exportin-T", "Extracellular matrix glycoprotein", "Extracellular matrix structural protein", "Extracellular structure", "Ezrin", "F-actin-capping protein subunit alpha-1", "F-actin-capping protein subunit alpha-2", "F-actin-capping protein subunit beta", "F-type ATPase", "F-type and V-type ATPases", "FACT complex subunit SPT16", "FAD-dependent oxidoreductase domain-containing protein 1", "FRAP subfamily", "FRAY subfamily", "Far upstream element-binding protein 1", "Far upstream element-binding protein 2", "Far upstream element-binding protein 3", "Farnesyl pyrophosphate synthase", "Fascin", "Fatty acid synthase", "Ferrochelatase, mitochondrial", "Flap endonuclease 1", "Flavin reductase (NADPH)", "Folate transporter 1", "Fragile X mental retardation syndrome-related protein 1", "Fragile X mental retardation syndrome-related protein 2", "Fumarate hydratase, mitochondrial", "G patch domain-containing protein 4", "G-patch domain and KOW motifs-containing protein", "G-protein", "G-protein coupled receptor", "G-protein modulator", "G-rich sequence factor 1", "G2/mitotic-specific cyclin-B1", "GC-rich sequence DNA-binding factor 2", "GDP-mannose 4,6 dehydratase", "GEK subfamily", "GHMP kinase family", "GMP synthase [glutamine-hydrolyzing]", "GPI-anchor transamidase", "GPN-loop GTPase 1", "GSK family", "GSK subfamily", "GTP-binding nuclear protein Ran", "GTP-binding protein 1", "GTP-binding protein Rheb", "GTPase Era, mitochondrial", "GTPase-activating protein and VPS9 domain-containing protein 1", "Galactokinase", "Galactosidase", "Gamma-adducin", "Gamma-aminobutyric acid receptor-associated protein-like 2", "Gamma-enolase", "Gamma-glutamyl hydrolase", "Gamma-taxilin", "Gamma-tubulin complex component 2", "Gamma-tubulin complex component 3", "Ganglioside GM2 activator", "General transcription factor 3C polypeptide 3", "General transcription factor 3C polypeptide 5", "General transcription factor IIF subunit 1", "General transcription factor IIF subunit 2", "General vesicular transport factor p115", "Geranylgeranyl transferase type-1 subunit beta", "Geranylgeranyl transferase type-2 subunit alpha", "Geranylgeranyl transferase type-2 subunit beta", "Girdin", "Glia maturation factor beta", "Glucosamine-6-phosphate isomerase 1", "Glucose-6-phosphate 1-dehydrogenase", "Glucose-6-phosphate isomerase", "Glucose-induced degradation protein 8 homolog", "Glucosidase", "Glucosidase 2 subunit beta", "Glutamate dehydrogenase 1, mitochondrial", "Glutamate--cysteine ligase regulatory subunit", "Glutaminase kidney isoform, mitochondrial", "Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1", "Glutamine--tRNA ligase", "Glutamine-rich protein 1", "Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial", "Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial", "Glutaredoxin-3", "Glutaredoxin-related protein 5, mitochondrial", "Glutathione hydrolase 7", "Glutathione reductase, mitochondrial", "Glutathione synthetase", "Glyceraldehyde-3-phosphate dehydrogenase", "Glycerol-3-phosphate dehydrogenase, mitochondrial", "Glycerol-3-phosphate phosphatase", "Glycine dehydrogenase (decarboxylating), mitochondrial", "Glycine--tRNA ligase", "Glycogen debranching enzyme", "Glycogen phosphorylase, brain form", "Glycogen phosphorylase, liver form", "Glycogen synthase kinase-3 alpha", "Glycogen synthase kinase-3 beta", "Glycogenin-1", "Glycosidase", "Glycosylase", "Glycosyltransferase", "Glycylpeptide N-tetradecanoyltransferase 1", "Glyoxylate reductase/hydroxypyruvate reductase", "Golgi pH regulator family", "Golgi ph regulator b", "Golgin subfamily A member 2", "Group XV phospholipase A2", "Growth factor", "GrpE protein homolog 1, mitochondrial", "Gtp:amp phosphotransferase ak3, mitochondrial", "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5", "Guanine nucleotide-binding protein G(i) subunit alpha-1", "Guanine nucleotide-binding protein G(i) subunit alpha-2", "Guanine nucleotide-binding protein G(k) subunit alpha", "Guanine nucleotide-binding protein subunit alpha-11", "Guanine nucleotide-binding protein subunit alpha-13", "Guanyl-nucleotide exchange factor", "H(+)/Cl(-) exchange transporter 3", "H/ACA ribonucleoprotein complex subunit 1", "H/ACA ribonucleoprotein complex subunit 2", "HBS1-like protein", "HDAC class I", "HDAC class III", "HEAT repeat-containing protein 1", "HEAT repeat-containing protein 6", "HIV Tat-specific factor 1", "Haloacid dehalogenase-like hydrolase domain-containing 5", "Haloacid dehalogenase-like hydrolase domain-containing protein 2", "Heat shock protein 75 kDa, mitochondrial", "Heat shock protein HSP 90-alpha", "Heat shock protein HSP 90-beta", "Helicase", "Helix-turn-helix transcription factor", "Hepatoma-derived growth factor", "Hepatoma-derived growth factor-related protein 2", "Heterogeneous nuclear ribonucleoprotein F", "Heterogeneous nuclear ribonucleoprotein H", "Heterogeneous nuclear ribonucleoprotein H2", "Heterogeneous nuclear ribonucleoprotein H3", "Heterogeneous nuclear ribonucleoprotein K", "Heterogeneous nuclear ribonucleoprotein M", "Heterogeneous nuclear ribonucleoprotein Q", "Heterogeneous nuclear ribonucleoprotein R", "Heterotrimeric G-protein", "Hexokinase family", "Hexokinase-1", "Hexokinase-2", "High mobility group protein B1", "High mobility group protein B2", "High mobility group protein B3", "High mobility group protein HMG-I/HMG-Y", "Histidine triad nucleotide-binding protein 2, mitochondrial", "Histidine triad nucleotide-binding protein 3", "Histone", "Histone H1.0", "Histone H1.2", "Histone H1.3", "Histone H1.4", "Histone H1x", "Histone H2AX", "Histone H4", "Histone acetyltransferase KAT7", "Histone acetyltransferase type B catalytic subunit", "Histone deacetylase", "Histone deacetylase 1", "Histone deacetylase 2", "Histone deacetylase complex subunit SAP18", "Histone-arginine methyltransferase CARM1", "Histone-lysine N-methyltransferase EHMT2", "Histone-lysine N-methyltransferase NSD2", "Histone-lysine N-methyltransferase SETD7", "Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific", "Homeobox protein CDX-2", "Homeodomain transcription factor", "Hormone", "Hsp90 co-chaperone Cdc37", "Hsp90 family chaperone", "Huntingtin-interacting protein 1", "Hydrolase", "Hydroxylase", "Hydroxymethylglutaryl-CoA lyase, mitochondrial", "Hypoxanthine-guanine phosphoribosyltransferase", "IKK family", "ILK subfamily", "INSR family", "Immune response", "Immunoglobulin fold transcription factor", "Immunoglobulin superfamily cell adhesion molecule", "Immunoglobulin-binding protein 1", "Importin subunit alpha-1", "Importin subunit alpha-3", "Importin subunit alpha-4", "Importin subunit alpha-5", "Importin subunit alpha-7", "Importin subunit beta-1", "Importin-11", "Importin-4", "Importin-5", "Importin-7", "Importin-8", "Importin-9", "Inactive tyrosine-protein kinase 7", "Induced myeloid leukemia cell differentiation protein Mcl-1", "Inhibitor of nuclear factor kappa-b kinase subunit alpha", "Inhibitor of nuclear factor kappa-b kinase subunit beta", "Inorganic pyrophosphatase", "Inorganic pyrophosphatase 2, mitochondrial", "Inosine triphosphate pyrophosphatase", "Inosine-5'-monophosphate dehydrogenase 1", "Inosine-5'-monophosphate dehydrogenase 2", "Inositol monophosphatase 1", "Inositol monophosphatase 3", "Inositol polyphosphate 5-phosphatase OCRL-1", "Insulin-degrading enzyme", "Insulin-like growth factor 1 receptor", "Insulin-like growth factor 2 mRNA-binding protein 1", "Insulin-like growth factor 2 mRNA-binding protein 2", "Insulin-like growth factor 2 mRNA-binding protein 3", "Integrator complex subunit 11", "Integrin beta-1", "Integrin-linked kinase-associated serine/threonine phosphatase 2C", "Integrin-linked protein kinase", "Interferon gamma receptor 1", "Interferon-induced, double-stranded rna-activated protein kinase", "Interleukin enhancer-binding factor 3", "Intermediate filament", "Intermediate filament binding protein", "Intersectin-2", "Intracellular calcium-sensing protein", "Intracellular chloride channel (clic) family", "Intracellular chloride channel (icc) family", "Ion channel", "Isoaspartyl peptidase/L-asparaginase", "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial", "Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial", "Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial", "Isoleucine--tRNA ligase, cytoplasmic", "Isoleucine--tRNA ligase, mitochondrial", "Isomerase", "Isopentenyl-diphosphate Delta-isomerase 1", "Isovaleryl-CoA dehydrogenase, mitochondrial", "Jumonji domain-containing", "KH domain-containing, RNA-binding, signal transduction-associated protein 1", "KH domain-containing, RNA-binding, signal transduction-associated protein 3", "KRAB box transcription factor", "KRR1 small subunit processome component homolog", "Kinase", "Kinase activator", "Kinase inhibitor", "Kinase modulator", "Kinesin heavy chain isoform 5C", "Kinesin-1 heavy chain", "Kinesin-like protein KIF11", "Kinesin-like protein KIF14", "Kinesin-like protein KIF15", "Kinesin-like protein KIF1B", "Kinesin-like protein KIF20A", "Kinesin-like protein KIF20B", "Kinesin-like protein KIF22", "Kinesin-like protein KIF23", "Kinesin-like protein KIF2A", "Kinesin-like protein KIF2C", "Kinesin-like protein KIF3A", "Kinesin-like protein KIFC1", "Kinetochore protein NDC80 homolog", "Kinetochore protein Nuf2", "L-2-hydroxyglutarate dehydrogenase, mitochondrial", "L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase", "L-lactate dehydrogenase A chain", "L-lactate dehydrogenase B chain", "LIM domain and actin-binding protein 1", "LU7TM family", "La-related protein 1", "La-related protein 4", "La-related protein 4B", "La-related protein 7", "Lamin-B receptor", "Lamina-associated polypeptide 2, isoform alpha", "Laminin subunit beta-1", "Laminin subunit gamma-1", "Lanosterol 14-alpha demethylase", "Large proline-rich protein BAG6", "Lethal(2) giant larvae protein homolog 1", "Leucine-rich repeat and WD repeat-containing protein 1", "Leucine-rich repeat-containing protein 47", "Leucyl-cystinyl aminopeptidase", "Leukocyte elastase inhibitor", "Ligase", "Lipase", "Lipid kinase", "Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial", "Lon protease homolog, mitochondrial", "Long-chain fatty acid transport protein 4", "Long-chain-fatty-acid--CoA ligase 1", "Long-chain-fatty-acid--CoA ligase 3", "Long-chain-fatty-acid--CoA ligase 4", "Long-chain-fatty-acid--CoA ligase 6", "Low density lipoprotein receptor adapter protein 1", "Lupus La protein", "Lyase", "Lymphokine-activated killer t-cell-originated protein kinase", "Lysine demethylase", "Lysine--tRNA ligase", "Lysine-specific demethylase", "Lysine-specific demethylase 3B", "Lysine-specific histone demethylase 1A", "Lysine-specific histone demethylase 1B", "Lysophosphatidic acid phosphatase type 6", "Lysophosphatidylcholine acyltransferase 1", "Lysophospholipid acyltransferase 7", "Lysosomal Pro-X carboxypeptidase", "Lysosomal acid lipase/cholesteryl ester hydrolase", "Lysosomal acid phosphatase", "Lysosomal alpha-glucosidase", "Lysosomal protective protein", "Lysosomal thioesterase PPT2", "Lysosome membrane protein 2", "Lysosome-associated membrane glycoprotein 1", "Lysosome-associated membrane glycoprotein 2", "M-phase inducer phosphatase 3", "MAGUK p55 subfamily member 2", "MAGUK p55 subfamily member 6", "MAGUK p55 subfamily member 7", "MAP7 domain-containing protein 1", "MAPK family", "MARK subfamily", "MCU family", "MFS-type transporter SLC18B1", "MLK family", "MMS19 nucleotide excision repair protein homolog", "MOB-like protein phocein", "MST subfamily", "MTSS1-like protein", "Magnesium transporter protein 1", "Major histocompatibility complex antigen", "Malate dehydrogenase, cytoplasmic", "Malate dehydrogenase, mitochondrial", "Malignant T-cell-amplified sequence 1", "Mannose-6-phosphate isomerase", "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB", "Mediator of RNA polymerase II transcription subunit 14", "Mediator of RNA polymerase II transcription subunit 21", "Medium-chain specific acyl-CoA dehydrogenase, mitochondrial", "Melanoma inhibitory activity protein 2", "Melanoma-associated antigen D1", "Melanoma-associated antigen D2", "Membrane trafficking regulatory protein", "Membrane-associated progesterone receptor component 1", "Membrane-associated progesterone receptor component 2", "Metalloprotease", "Metastasis-associated protein MTA1", "Metastasis-associated protein MTA2", "Methionine aminopeptidase 1", "Methyl-CpG-binding domain", "Methyl-CpG-binding protein 2", "Methyl-lysine/arginine binding protein", "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial", "Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial", "Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial", "Methylmalonyl-CoA mutase, mitochondrial", "Methylosome subunit pICln", "Methylsterol monooxygenase 1", "Methyltransferase", "Mevalonate kinase", "Mevalonate kinase subfamily", "Microfibrillar-associated protein 1", "Microsomal glutathione S-transferase 2", "Microsomal glutathione S-transferase 3", "Microtubule binding motor protein", "Microtubule family cytoskeletal protein", "Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5", "Microtubule-associated protein 1A", "Microtubule-associated protein 1B", "Microtubule-associated protein 1S", "Microtubule-associated protein RP/EB family member 1", "Microtubule-associated protein RP/EB family member 2", "Minor histocompatibility antigen H13", "Miscellaneous SLC25 mitochondrial transporters", "Mitochondrial 2-oxoglutarate/malate carrier protein", "Mitochondrial Rho GTPase 1", "Mitochondrial Rho GTPase 2", "Mitochondrial amino acid transporter subfamily", "Mitochondrial carnitine/acylcarnitine carrier protein", "Mitochondrial carrier homolog 1", "Mitochondrial carrier homolog 2", "Mitochondrial di- and tri-carboxylic acid transporter subfamily", "Mitochondrial dicarboxylate carrier", "Mitochondrial folate transporter/carrier", "Mitochondrial glutamate carrier 1", "Mitochondrial import receptor subunit TOM20 homolog", "Mitochondrial import receptor subunit TOM40 homolog", "Mitochondrial inner membrane protein OXA1L", "Mitochondrial intermediate peptidase", "Mitochondrial nucleotide transporter subfamily", "Mitochondrial ornithine transporter 1", "Mitochondrial phosphate transporters", "Mitochondrial proton/calcium exchanger protein", "Mitochondrial pyruvate carrier 2", "Mitochondrial-processing peptidase subunit alpha", "Mitochondrial-processing peptidase subunit beta", "Mitofusin-1", "Mitofusin-2", "Mitogen-activated protein kinase 1", "Mitogen-activated protein kinase 14", "Mitogen-activated protein kinase 3", "Mitotic checkpoint protein BUB3", "Mitotic checkpoint serine/threonine-protein kinase bub1", "Mitotic checkpoint serine/threonine-protein kinase bub1 beta", "Moesin", "Molybdate-anion transporter", "Monoacylglycerol lipase ABHD12", "Monoacylglycerol lipase ABHD6", "Monocarboxylate transporter 1", "Monofunctional C1-tetrahydrofolate synthase, mitochondrial", "Mortality factor 4-like protein 1", "Mpv17-like protein 2", "Multidrug resistance protein 1", "Multidrug resistance-associated protein 4", "Multifunctional protein ADE2", "Mutase", "Myb-binding protein 1A", "Myelin expression factor 2", "Myosin light polypeptide 6", "Myosin phosphatase Rho-interacting protein", "Myotubularin-related protein 2", "N-acetyl-D-glucosamine kinase", "N-acetylgalactosaminyltransferase 7", "N-acetylglucosamine-6-sulfatase", "N-acylneuraminate cytidylyltransferase", "N-alpha-acetyltransferase 10", "N-alpha-acetyltransferase 15, NatA auxiliary subunit", "N-alpha-acetyltransferase 16, NatA auxiliary subunit", "N-alpha-acetyltransferase 35, NatC auxiliary subunit", "N-alpha-acetyltransferase 50", "N-terminal Xaa-Pro-Lys N-methyltransferase 1", "NAD kinase 2, mitochondrial", "NAD(P) transhydrogenase, mitochondrial", "NAD-dependent malic enzyme, mitochondrial", "NAD-dependent protein deacetylase sirtuin-1", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial", "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial", "NADH-ubiquinone oxidoreductase chain 5", "NADPH:adrenodoxin oxidoreductase, mitochondrial", "NAK family", "NEDD8-activating enzyme E1 catalytic subunit", "NEDD8-activating enzyme E1 regulatory subunit", "NEK family", "NF-kappa-B-repressing factor", "NHP2-like protein 1", "NRBP family", "NSFL1 cofactor p47", "Na+/K+-ATPases", "Nardilysin", "Neuferricin", "Neural Wiskott-Aldrich syndrome protein", "Neurolysin, mitochondrial", "Neuropathy target esterase", "Neuroplastin", "Neutral alpha-glucosidase AB", "Neutral amino acid transporter B(0)", "Neutral amino acid transporter subfamily", "Nf-kappa-b essential modulator", "Nibrin", "Nicotinamide phosphoribosyltransferase", "Nipped-B-like protein", "Nischarin", "Non-POU domain-containing octamer-binding protein", "Non-histone chromosomal protein HMG-14", "Non-histone chromosomal protein HMG-17", "Non-motor actin binding protein", "Non-motor microtubule binding protein", "Non-protein kinase", "Nuclear RNA export factor 1", "Nuclear cap-binding protein subunit 1", "Nuclear factor NF-kappa-B p105 subunit", "Nuclear migration protein nudC", "Nuclear pore complex protein Nup107", "Nuclear pore complex protein Nup153", "Nuclear pore complex protein Nup160", "Nuclear pore complex protein Nup214", "Nuclear pore complex protein Nup85", "Nuclear pore complex protein Nup88", "Nuclear pore complex protein Nup93", "Nuclear pore complex protein Nup98-Nup96", "Nuclear pore glycoprotein p62", "Nuclear pore membrane glycoprotein 210", "Nuclear receptor coactivator 5", "Nuclear receptor corepressor 1", "Nuclear receptor-binding protein", "Nuclease", "Nucleic acid binding", "Nucleobindin-1", "Nucleobindin-2", "Nucleolar MIF4G domain-containing protein 1", "Nucleolar complex protein 4 homolog", "Nucleolar protein 14", "Nucleolar protein 56", "Nucleolar protein 58", "Nucleolar protein 6", "Nucleolar protein 9", "Nucleolin", "Nucleophosmin", "Nucleoporin Nup37", "Nucleoporin SEH1", "Nucleoporin p54", "Nucleoside diphosphate kinase 3", "Nucleoside diphosphate kinase A", "Nucleoside diphosphate kinase B", "Nucleoside kinase", "Nucleosome assembly protein 1-like 1", "Nucleosome assembly protein 1-like 4", "Nucleotide kinase", "Nucleotide phosphatase", "Nucleotidyltransferase", "NudC domain-containing protein 2", "NudC domain-containing protein 3", "OCIA domain-containing protein 1", "OTU domain-containing protein 4", "OTU domain-containing protein 7B", "Obg-like ATPase 1", "Origin recognition complex subunit 3", "Origin recognition complex subunit 5", "Ornithine aminotransferase, mitochondrial", "Other 7TM proteins", "Other group", "Other small molecule kinase", "Oxidase", "Oxidoreductase", "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial", "Oxygenase", "P-type ATPases", "P38 subfamily", "P53-like transcription factor", "PAKA subfamily", "PAKB subfamily", "PC4 and SFRS1-interacting protein", "PDHK family", "PDZ and LIM domain protein 1", "PDZ and LIM domain protein 3", "PDZ and LIM domain protein 5", "PDZ and LIM domain protein 7", "PEK family", "PH-interacting protein", "PHD finger protein 10", "PHD finger protein 3", "PHD finger protein 6", "PI3/PI4 kinase family", "PIKK family", "PIN2/TERF1-interacting telomerase inhibitor 1", "PITSLRE subfamily", "PKA family", "PKC delta subfamily", "PKC family", "PKN family", "PLK family", "PMS1 protein homolog 1", "Paired amphipathic helix protein Sin3a", "Palmitoyl-protein thioesterase 1", "Pantothenate kinase 4", "Paraspeckle component 1", "Pentatricopeptide repeat-containing protein 1, mitochondrial", "Peptidyl-prolyl cis-trans isomerase FKBP1A", "Peptidyl-prolyl cis-trans isomerase FKBP4", "Peptidyl-prolyl cis-trans isomerase FKBP5", "Peptidyl-prolyl cis-trans isomerase-like 1", "Peptidyl-prolyl cis-trans isomerase-like 3", "Peptidylprolyl isomerase domain and WD repeat-containing protein 1", "Perilipin-3", "Periodic tryptophan protein 1 homolog", "Peripheral plasma membrane protein cask", "Peroxidase", "Peroxiredoxin-2", "Peroxiredoxin-4", "Peroxiredoxin-6", "Peroxisomal NADH pyrophosphatase NUDT12", "Peroxisomal acyl-coenzyme A oxidase 1", "Peroxisomal biogenesis factor 19", "Peroxisomal membrane protein 2", "Peroxisomal membrane protein PEX14", "Peroxisomal membrane protein PMP34", "Peroxisomal targeting signal 1 receptor", "Peroxisomal trans-2-enoyl-CoA reductase", "Pescadillo homolog", "Phenylalanine--tRNA ligase beta subunit", "Phosphatase", "Phosphatase activator", "Phosphatase inhibitor", "Phosphatase modulator", "Phosphate carrier protein, mitochondrial", "Phosphatidylethanolamine-binding protein 1", "Phosphatidylinositol 3-kinase catalytic subunit type 3", "Phosphatidylinositol 4-kinase alpha", "Phosphatidylinositol 4-kinase beta", "Phosphatidylinositol 4-kinase type 2-alpha", "Phosphatidylinositol 4-phosphate 3-kinase c2 domain-containing subunit alpha", "Phosphatidylinositol 5-phosphate 4-kinase type-2 beta", "Phosphatidylinositol transfer protein alpha isoform", "Phosphatidylinositol transfer protein beta isoform", "Phosphatidylinositol-binding clathrin assembly protein", "Phosphatidylserine synthase 1", "Phosphodiesterase", "Phosphoenolpyruvate carboxykinase [GTP] family", "Phosphoenolpyruvate carboxykinase [gtp], mitochondrial", "Phosphofructokinase type A (PFKA) family", "Phosphoglycerate kinase 1", "Phosphoglycerate kinase family", "Phosphoinositide 3-kinase (PI3K) family", "Phosphoinositide 3-kinase regulatory subunit 4", "Phospholipase", "Phospholipase A-2-activating protein", "Phosphoribosyl pyrophosphate synthase-associated protein 1", "Phosphoribosyl pyrophosphate synthase-associated protein 2", "Phosphorylase", "Phosphorylated adapter RNA export protein", "Phosphoserine phosphatase", "Pirin", "Plasma membrane calcium-transporting ATPase 1", "Plasminogen activator inhibitor 1 RNA-binding protein", "Plastin-1", "Plastin-3", "Plectin", "Pogo transposable element with ZNF domain", "Poly(A) RNA polymerase, mitochondrial", "Poly(A) polymerase alpha", "Poly(A)-specific ribonuclease PARN", "Poly(ADP-ribose) glycohydrolase", "Poly(rC)-binding protein 1", "Poly(rC)-binding protein 2", "Polyadenylate-binding protein-interacting protein 1", "Polycomb protein SUZ12", "Polyglutamine-binding protein 1", "Polymerase", "Polymerase delta-interacting protein 3", "Polypeptide N-acetylgalactosaminyltransferase 1", "Polypeptide N-acetylgalactosaminyltransferase 2", "Polyribonucleotide nucleotidyltransferase 1, mitochondrial", "Porphobilinogen deaminase", "Pre-mRNA-processing factor 39", "Pre-mRNA-processing factor 6", "Pre-mRNA-processing-splicing factor 8", "Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15", "Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16", "Pre-mRNA-splicing factor CWC22 homolog", "Pre-mRNA-splicing factor RBM22", "Pre-mRNA-splicing factor SLU7", "Pre-mRNA-splicing factor SPF27", "Pre-mRNA-splicing factor SYF1", "Prefoldin subunit 1", "Prefoldin subunit 2", "Prefoldin subunit 3", "Prefoldin subunit 5", "Presequence protease, mitochondrial", "Primase", "Probable 18S rRNA (guanine-N(7))-methyltransferase", "Probable ATP-dependent RNA helicase DHX37", "Probable ATP-dependent RNA helicase DHX40", "Probable E3 ubiquitin-protein ligase makorin-2", "Probable RNA-binding protein 19", "Probable U3 small nucleolar RNA-associated protein 11", "Probable global transcription activator SNF2L1", "Probable glutamate--tRNA ligase, mitochondrial", "Probable histidine--tRNA ligase, mitochondrial", "Probable leucine--tRNA ligase, mitochondrial", "Probable ribosome biogenesis protein RLP24", "Probable serine carboxypeptidase CPVL", "Probable tRNA N6-adenosine threonylcarbamoyltransferase", "Probable tRNA pseudouridine synthase 1", "Procollagen galactosyltransferase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2", "Programmed cell death 6-interacting protein", "Programmed cell death protein 5", "Prolactin regulatory element-binding protein", "Proliferating cell nuclear antigen", "Prolyl 3-hydroxylase 1", "Prolyl endopeptidase", "Propionyl-CoA carboxylase alpha chain, mitochondrial", "Propionyl-CoA carboxylase beta chain, mitochondrial", "Prostaglandin E synthase 2", "Prostaglandin E synthase 3", "Prostaglandin reductase 1", "Prostaglandin reductase 2", "Prostaglandin reductase 3", "Protease", "Protease inhibitor", "Proteasome inhibitor PI31 subunit", "Protein AATF", "Protein BUD31 homolog", "Protein CMSS1", "Protein DDI1 homolog 2", "Protein ERGIC-53", "Protein FAM177A1", "Protein LSM14 homolog A", "Protein LSM14 homolog B", "Protein NDRG3", "Protein PAT1 homolog 1", "Protein PRRC2A", "Protein PRRC2B", "Protein PRRC2C", "Protein RRP5 homolog", "Protein Red", "Protein S100-A10", "Protein S100-A11", "Protein S100-A13", "Protein SCO1 homolog, mitochondrial", "Protein SCO2 homolog, mitochondrial", "Protein SET", "Protein VAC14 homolog", "Protein Wiz", "Protein XRP2", "Protein arginine N-methyltransferase 1", "Protein arginine N-methyltransferase 3", "Protein arginine N-methyltransferase 5", "Protein arginine methyltransferase", "Protein farnesyltransferase subunit beta", "Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha", "Protein gpr107", "Protein kinase", "Protein kinase C and casein kinase substrate in neurons protein 2", "Protein kinase C and casein kinase substrate in neurons protein 3", "Protein kinase c delta type", "Protein lin-28 homolog B", "Protein methyltransferase", "Protein pelota homolog", "Protein phosphatase", "Protein phosphatase 1G", "Protein phosphatase methylesterase 1", "Protein polybromo-1", "Protein quaking", "Protein regulator of cytokinesis 1", "Protein spinster homolog 1", "Protein strawberry notch homolog 1", "Protein transport protein Sec23A", "Protein transport protein Sec24A", "Protein transport protein Sec24C", "Protein transport protein Sec31A", "Protein transport protein Sec61 subunit alpha isoform 1", "Protein tweety homolog 3", "Protein unc-119 homolog B", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase", "Protein/nucleic acid deglycase DJ-1", "Pterin-4-alpha-carbinolamine dehydratase", "Pumilio homolog 1", "Purine nucleoside phosphorylase", "Puromycin-sensitive aminopeptidase", "Putative ATP-dependent RNA helicase DHX57", "Putative oxidoreductase GLYR1", "Putative phospholipase B-like 2", "Pyridoxal kinase", "Pyridoxine kinase family", "Pyridoxine-5'-phosphate oxidase", "Pyrophosphatase", "Pyruvate carboxylase, mitochondrial", "Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial", "Pyruvate kinase pkm", "RAD53 family", "RIPK family", "RNA 3'-terminal phosphate cyclase", "RNA 3'-terminal phosphate cyclase-like protein", "RNA binding protein", "RNA helicase", "RNA polymerase II elongation factor ELL", "RNA polymerase II subunit A C-terminal domain phosphatase", "RNA-binding motif protein, X chromosome", "RNA-binding protein 12", "RNA-binding protein 12B", "RNA-binding protein 14", "RNA-binding protein 26", "RNA-binding protein 27", "RNA-binding protein 3", "RNA-binding protein 4", "RNA-binding protein EWS", "RNA-binding protein FUS", "RNA-binding protein Nova-1", "RNA-binding protein with multiple splicing", "RNA-binding protein with serine-rich domain 1", "ROCK subfamily", "RSK family", "RSK subfamily", "Rab GDP dissociation inhibitor alpha", "Rab GDP dissociation inhibitor beta", "Rab GTPase-activating protein 1", "Rab3 GTPase-activating protein non-catalytic subunit", "Rac GTPase-activating protein 1", "Rac-alpha serine/threonine-protein kinase", "Radixin", "RalBP1-associated Eps domain-containing protein 1", "Ran GTPase-activating protein 1", "Ran-binding protein 3", "Ran-binding protein 6", "Ran-binding protein 9", "Ran-specific GTPase-activating protein", "Rap guanine nucleotide exchange factor 2", "Rap guanine nucleotide exchange factor 6", "Ras GTPase-activating protein-binding protein 1", "Ras GTPase-activating protein-binding protein 2", "Ras GTPase-activating-like protein IQGAP1", "Ras GTPase-activating-like protein IQGAP2", "Ras-related C3 botulinum toxin substrate 1", "Ras-related protein R-Ras2", "Ras-related protein Ral-A", "Reader", "Receptor", "Receptor expression-enhancing protein 3", "Receptor expression-enhancing protein 4", "Receptor expression-enhancing protein 5", "Receptor-interacting serine/threonine-protein kinase 1", "Receptor-type tyrosine-protein phosphatase F", "Reductase", "Regulation of nuclear pre-mRNA domain-containing protein 1A", "Regulation of nuclear pre-mRNA domain-containing protein 1B", "Regulation of nuclear pre-mRNA domain-containing protein 2", "Regulator of nonsense transcripts 1", "Regulator of nonsense transcripts 2", "Rel homology transcription factor", "Remodeling and spacing factor 1", "Renin receptor", "Replication factor C subunit 2", "Replication factor C subunit 3", "Replication factor C subunit 4", "Replication factor C subunit 5", "Replication origin binding protein", "Replication protein A 70 kDa DNA-binding subunit", "Reticulocalbin-1", "Reticulocalbin-2", "Retinal dehydrogenase 2", "Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta", "Retinoid-inducible serine carboxypeptidase", "Retinol dehydrogenase 11", "Retinol dehydrogenase 14", "Rho GDP-dissociation inhibitor 1", "Rho-associated protein kinase 1", "Rho-associated protein kinase 2", "Rho-related GTP-binding protein RhoG", "Ribonuclease H2 subunit A", "Ribonuclease P protein subunit p25-like protein", "Ribonuclease P protein subunit p30", "Ribonucleoprotein", "Ribonucleoprotein PTB-binding 1", "Ribonucleoside-diphosphate reductase large subunit", "Ribonucleoside-diphosphate reductase subunit M2", "Ribonucleoside-diphosphate reductase subunit M2 B", "Ribose-phosphate pyrophosphokinase 1", "Ribose-phosphate pyrophosphokinase 2", "Ribosomal L1 domain-containing protein 1", "Ribosomal RNA small subunit methyltransferase NEP1", "Ribosomal protein", "Ribosomal protein s6 kinase alpha-1", "Ribosomal protein s6 kinase alpha-3", "Ribosome biogenesis protein BOP1", "Ribosome biogenesis protein BRX1 homolog", "Ribosome biogenesis regulatory protein homolog", "Ribosome maturation protein SBDS", "Ribosome production factor 1", "Ribosome production factor 2 homolog", "Ribosome-recycling factor, mitochondrial", "S-adenosylhomocysteine hydrolase-like protein 1", "S-adenosylmethionine mitochondrial carrier protein", "S-adenosylmethionine synthase isoform type-2", "S-formylglutathione hydrolase", "S-methyl-5'-thioadenosine phosphorylase", "S-phase kinase-associated protein 1", "S1 RNA-binding domain-containing protein 1", "SCY1 family", "SEC23-interacting protein", "SET domain", "SLC superfamily of solute carriers", "SLC1 family of amino acid transporters", "SLC12 family of cation-coupled chloride transporters", "SLC16 family of monocarboxylate transporters", "SLC18 family of vesicular amine transporters", "SLC19 family of vitamin transporters", "SLC25 family of mitochondrial transporters", "SLC27 family of fatty acid transporters", "SLC3 and SLC7 families of heteromeric amino acid transporters (HATs)", "SLC3 family", "SLC30 zinc transporter family", "SLC35 family of nucleotide sugar transporters", "SLC38 family of sodium-dependent neutral amino acid transporters", "SLC54 Mitochondrial pyruvate carriers", "SLC55 Mitochondrial cation/proton exchangers", "SLC56 Sideroflexins", "SLC58 MagT-like magnesium transporter family", "SLC6 neurotransmitter transporter family", "SLC61 Molybdate transporter family", "SLC63 Sphingosine-phosphate transporters", "SLC64 Golgi Ca2+/H+ exchangers", "SLK subfamily", "SNARE protein", "SNW domain-containing protein 1", "SRPK family", "STAM-binding protein", "STE group", "STE20 family", "STE7 family", "SUMO-activating enzyme subunit 1", "SUMO-activating enzyme subunit 2", "SUN domain-containing protein 1", "SUN domain-containing protein 2", "SURP and G-patch domain-containing protein 1", "SURP and G-patch domain-containing protein 2", "SWI/SNF complex subunit SMARCC1", "SWI/SNF complex subunit SMARCC2", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1", "Sarcoplasmic/endoplasmic reticulum calcium ATPase 2", "Scavenger receptor class B member 1", "Scy1-like protein 2", "Sec1 family domain-containing protein 1", "Secretory carrier-associated membrane protein 2", "Secretory carrier-associated membrane protein 3", "Segment polarity protein dishevelled homolog DVL-2", "Selenide, water dikinase 1", "Selenocysteine-specific elongation factor", "Sentrin-specific protease 3", "Septin-11", "Septin-2", "Septin-6", "Septin-7", "Septin-9", "Serine hydroxymethyltransferase, cytosolic", "Serine hydroxymethyltransferase, mitochondrial", "Serine palmitoyltransferase 1", "Serine palmitoyltransferase 2", "Serine protease", "Serine protease inhibitor", "Serine--tRNA ligase, cytoplasmic", "Serine--tRNA ligase, mitochondrial", "Serine/arginine repetitive matrix protein 1", "Serine/arginine-rich splicing factor 1", "Serine/arginine-rich splicing factor 10", "Serine/arginine-rich splicing factor 11", "Serine/arginine-rich splicing factor 2", "Serine/arginine-rich splicing factor 3", "Serine/arginine-rich splicing factor 4", "Serine/arginine-rich splicing factor 5", "Serine/arginine-rich splicing factor 6", "Serine/arginine-rich splicing factor 7", "Serine/arginine-rich splicing factor 9", "Serine/threonine-protein kinase 26", "Serine/threonine-protein kinase 4", "Serine/threonine-protein kinase chk1", "Serine/threonine-protein kinase chk2", "Serine/threonine-protein kinase mark1", "Serine/threonine-protein kinase mark2", "Serine/threonine-protein kinase mrck beta", "Serine/threonine-protein kinase mtor", "Serine/threonine-protein kinase n1", "Serine/threonine-protein kinase n2", "Serine/threonine-protein kinase nek9", "Serine/threonine-protein kinase osr1", "Serine/threonine-protein kinase pak 1", "Serine/threonine-protein kinase pak 2", "Serine/threonine-protein kinase pak 4", "Serine/threonine-protein kinase plk1", "Serine/threonine-protein kinase prp4 homolog", "Serine/threonine-protein kinase tbk1", "Serine/threonine-protein kinase vrk1", "Serine/threonine-protein kinase vrk2", "Serine/threonine-protein kinase wnk1", "Serine/threonine-protein kinase wnk2", "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform", "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform", "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform", "Serine/threonine-protein phosphatase 2A activator", "Serine/threonine-protein phosphatase 4 regulatory subunit 1", "Serine/threonine-protein phosphatase 6 regulatory subunit 3", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit", "Serine/threonine-protein phosphatase PP1-beta catalytic subunit", "Serpin B6", "Serpin H1", "Set1/Ash2 histone methyltransferase complex subunit ASH2", "Sex comb on midleg-like protein 2", "Sialic acid synthase", "Sideroflexin-1", "Sideroflexin-2", "Sigma intracellular receptor 2", "Signal peptidase complex catalytic subunit SEC11A", "Signal peptidase complex subunit 2", "Signal peptide peptidase-like 2A", "Signal recognition particle 14 kDa protein", "Signal recognition particle 19 kDa protein", "Signal recognition particle 54 kDa protein", "Signal recognition particle 9 kDa protein", "Signal recognition particle receptor subunit alpha", "Signal recognition particle subunit SRP68", "Signal transducer and activator of transcription 1-alpha/beta", "Signal transducer and activator of transcription 3", "Signaling", "Single-stranded DNA-binding protein, mitochondrial", "Sister chromatid cohesion protein PDS5 homolog A", "Sister chromatid cohesion protein PDS5 homolog B", "Small GTPase", "Small nuclear ribonucleoprotein E", "Small nuclear ribonucleoprotein Sm D1", "Small nuclear ribonucleoprotein Sm D2", "Small nuclear ribonucleoprotein Sm D3", "Sodium-coupled neutral amino acid transporter 2", "Sodium-dependent neutral amino acid transporter B(0)AT2", "Sodium/potassium-transporting ATPase subunit alpha-1", "Sodium/potassium-transporting ATPase subunit beta-1", "Sodium/potassium-transporting ATPase subunit beta-3", "Solute carrier family 12 member 2", "Solute carrier family 25 member 33", "Solute carrier family 25 member 40", "Solute carrier family 35 member F2", "Sorbitol dehydrogenase", "Sortilin", "Sorting nexin-1", "Sorting nexin-2", "Spermatid perinuclear RNA-binding protein", "Spermidine synthase", "Sphingosine kinase 2", "Splicing factor 1", "Splicing factor 3A subunit 1", "Splicing factor 3A subunit 2", "Splicing factor 3A subunit 3", "Splicing factor 3B subunit 1", "Splicing factor 3B subunit 3", "Splicing factor 45", "Splicing factor U2AF 35 kDa subunit", "Splicing factor, arginine/serine-rich 15", "Splicing factor, proline- and glutamine-rich", "Splicing factor, suppressor of white-apricot homolog", "Splicing regulatory glutamine/lysine-rich protein 1", "Squalene monooxygenase", "Squamous cell carcinoma antigen recognized by T-cells 3", "Src substrate cortactin", "Srsf protein kinase 1", "Srsf protein kinase 2", "Staphylococcal nuclease domain-containing protein 1", "Ste20-like serine/threonine-protein kinase", "Sterol O-acyltransferase 1", "Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating", "Stomatin-like protein 2, mitochondrial", "Storage", "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial", "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial", "Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial", "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial", "Succinate-semialdehyde dehydrogenase, mitochondrial", "Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial", "Sulfhydryl oxidase 2", "Superoxide dismutase [Mn], mitochondrial", "Surfeit locus protein 6", "Survival motor neuron protein", "Synaptic functional regulator FMR1", "Synaptogyrin-2", "Synaptojanin-2-binding protein", "Synaptosomal-associated protein 23", "Synaptosomal-associated protein 29", "Syntaxin-12", "Syntaxin-18", "Syntaxin-4", "Syntaxin-6", "Syntaxin-7", "Syntaxin-8", "Syntaxin-binding protein 2", "Syntaxin-binding protein 3", "Syntenin-1", "System A-like transporters", "T-complex protein 1 subunit alpha", "T-complex protein 1 subunit beta", "T-complex protein 1 subunit delta", "T-complex protein 1 subunit epsilon", "T-complex protein 1 subunit eta", "T-complex protein 1 subunit gamma", "T-complex protein 1 subunit theta", "T-complex protein 1 subunit zeta", "T-complex protein 11-like protein 1", "TATA-binding protein-associated factor 2N", "TBC1 domain family member 10A", "TBC1 domain family member 10B", "TBC1 domain family member 13", "TBC1 domain family member 15", "TBC1 domain family member 17", "TBC1 domain family member 2B", "TBC1 domain family member 4", "TBC1 domain family member 8B", "TBC1 domain family member 9B", "THO complex subunit 1", "THO complex subunit 2", "THO complex subunit 3", "THO complex subunit 4", "TK group", "TKL group", "TOPK family", "TP53-binding protein 1", "TRIO family", "TTK family", "Target of EGR1 protein 1", "Targeting protein for Xklp2", "Terminal uridylyltransferase 4", "Testin", "Testis-specific Y-encoded-like protein 1", "Tetratricopeptide repeat protein 28", "Tgf-beta-activated kinase 1 and map3k7-binding protein 1", "Thimet oligopeptidase", "Thioredoxin domain-containing protein 12", "Thioredoxin domain-containing protein 17", "Thioredoxin domain-containing protein 9", "Thioredoxin reductase 1, cytoplasmic", "Thioredoxin, mitochondrial", "Thioredoxin-dependent peroxide reductase, mitochondrial", "Threonine--tRNA ligase, cytoplasmic", "Threonine--tRNA ligase, mitochondrial", "Thymidine kinase family", "Thymidine kinase, cytosolic", "Thymidylate kinase", "Thymidylate kinase family", "Thymidylate synthase", "Thyroid hormone receptor-associated protein 3", "Tight junction", "Tight junction protein ZO-1", "Tight junction protein ZO-2", "Torsin-1B", "Trafficking protein particle complex subunit 4", "Transaminase", "Transcription activator BRG1", "Transcription cofactor", "Transcription elongation factor A protein 1", "Transcription elongation factor SPT6", "Transcription elongation regulator 1", "Transcription factor", "Transcription initiation factor IIB", "Transcriptional activator protein Pur-alpha", "Transcriptional coactivator YAP1", "Transcriptional repressor CTCF", "Transcriptional repressor p66-alpha", "Transcriptional repressor p66-beta", "Transferase", "Transferrin receptor protein 1", "Transformer-2 protein homolog alpha", "Transformer-2 protein homolog beta", "Transforming protein RhoA", "Transgelin-2", "Transketolase", "Translation elongation factor", "Translation factor", "Translation initiation factor", "Translation initiation factor IF-2, mitochondrial", "Translation release factor", "Translationally-controlled tumor protein", "Translocation protein SEC63 homolog", "Translocon-associated protein subunit alpha", "Transmembrane 9 superfamily member 2", "Transmembrane 9 superfamily member 3", "Transmembrane 9 superfamily member 4", "Transmembrane emp24 domain-containing protein 10", "Transmembrane emp24 domain-containing protein 2", "Transmembrane emp24 domain-containing protein 5", "Transmembrane emp24 domain-containing protein 7", "Transmembrane emp24 domain-containing protein 9", "Transmembrane protein 165", "Transport and Golgi organization protein 1 homolog", "Transporter", "Transportin-1", "Transportin-3", "Tricarboxylate transport protein, mitochondrial", "Trifunctional enzyme subunit alpha, mitochondrial", "Trifunctional enzyme subunit beta, mitochondrial", "Trifunctional purine biosynthetic protein adenosine-3", "Triosephosphate isomerase", "Tripeptidyl-peptidase 1", "Tripeptidyl-peptidase 2", "Triple functional domain protein", "Trophoblast glycoprotein", "Tropomodulin-1", "Tropomodulin-3", "Tropomyosin alpha-1 chain", "Tropomyosin alpha-3 chain", "Tropomyosin alpha-4 chain", "Tryptophan--tRNA ligase, cytoplasmic", "Tuberin", "Tubulin", "Tubulin beta chain", "Tubulin beta-2B chain", "Tubulin beta-3 chain", "Tubulin beta-4A chain", "Tubulin beta-4B chain", "Tubulin beta-6 chain", "Tubulin-folding cofactor B", "Tubulin-specific chaperone A", "Tubulin-specific chaperone C", "Tubulin-specific chaperone D", "Tubulin-specific chaperone E", "Tudor and KH domain-containing protein", "Tudor domain", "Tudor domain-containing protein 7", "Tuftelin-interacting protein 11", "Tumor susceptibility gene 101 protein", "Twinfilin-1", "Twinfilin-2", "Twinkle protein, mitochondrial", "Type II PI4K subfamily", "Type II cytokine receptor", "Type III PI4K subfamily", "Tyrosine--tRNA ligase, cytoplasmic", "Tyrosine--tRNA ligase, mitochondrial", "Tyrosine-protein kinase csk", "Tyrosine-protein phosphatase non-receptor type 9", "U1 small nuclear ribonucleoprotein 70 kDa", "U1 small nuclear ribonucleoprotein A", "U2 small nuclear ribonucleoprotein A'", "U2 small nuclear ribonucleoprotein B''", "U2 snRNP-associated SURP motif-containing protein", "U3 small nucleolar RNA-associated protein 14 homolog A", "U3 small nucleolar RNA-associated protein 6 homolog", "U3 small nucleolar ribonucleoprotein protein IMP3", "U3 small nucleolar ribonucleoprotein protein MPP10", "U4/U6 small nuclear ribonucleoprotein Prp3", "U4/U6 small nuclear ribonucleoprotein Prp31", "U4/U6 small nuclear ribonucleoprotein Prp4", "U4/U6.U5 tri-snRNP-associated protein 1", "U4/U6.U5 tri-snRNP-associated protein 2", "U6 snRNA-associated Sm-like protein LSm2", "U6 snRNA-associated Sm-like protein LSm6", "UDP-glucose:glycoprotein glucosyltransferase 1", "UMP-CMP kinase", "UV excision repair protein RAD23 homolog A", "UV excision repair protein RAD23 homolog B", "Ubiquitin carboxyl-terminal hydrolase 10", "Ubiquitin carboxyl-terminal hydrolase 11", "Ubiquitin carboxyl-terminal hydrolase 14", "Ubiquitin carboxyl-terminal hydrolase 15", "Ubiquitin carboxyl-terminal hydrolase 28", "Ubiquitin carboxyl-terminal hydrolase 47", "Ubiquitin carboxyl-terminal hydrolase 5", "Ubiquitin carboxyl-terminal hydrolase 7", "Ubiquitin carboxyl-terminal hydrolase isozyme L5", "Ubiquitin conjugation factor E4 A", "Ubiquitin thioesterase OTUB1", "Ubiquitin-conjugating enzyme E2 L3", "Ubiquitin-like modifier-activating enzyme 1", "Ubiquitin-like modifier-activating enzyme 5", "Ubiquitin-like modifier-activating enzyme 6", "Ubiquitin-like-conjugating enzyme ATG3", "Ubiquitin-protein ligase", "Unclassified protein", "Unconventional myosin-Ib", "Unconventional myosin-Ic", "Unconventional myosin-Id", "Unconventional myosin-VI", "Upstream-binding protein 1", "Uridine kinase family", "Uridine-cytidine kinase 2", "V-type ATPase", "V-type proton ATPase 116 kDa subunit a isoform 1", "V-type proton ATPase 116 kDa subunit a isoform 2", "V-type proton ATPase catalytic subunit A", "V-type proton ATPase subunit B, brain isoform", "V-type proton ATPase subunit C 1", "V-type proton ATPase subunit D", "V-type proton ATPase subunit H", "VPS15 family", "VRK family", "Vacuolar protein sorting-associated protein 18 homolog", "Vacuolar protein sorting-associated protein 26A", "Vacuolar protein sorting-associated protein 26B", "Vacuolar protein sorting-associated protein 29", "Vacuolar protein sorting-associated protein 33A", "Vacuolar protein sorting-associated protein 33B", "Vacuolar protein sorting-associated protein 35", "Vacuolar protein sorting-associated protein 45", "Vacuolar protein sorting-associated protein 4A", "Vacuolar protein sorting-associated protein 4B", "Very long-chain specific acyl-CoA dehydrogenase, mitochondrial", "Very-long-chain enoyl-CoA reductase", "Vesicle coat protein", "Vesicle transport through interaction with t-SNAREs homolog 1B", "Vesicle-associated membrane protein 7", "Vesicle-associated membrane protein-associated protein A", "Vesicle-associated membrane protein-associated protein B/C", "Vesicle-fusing ATPase", "Vesicular integral-membrane protein VIP36", "Vitamin K epoxide reductase complex subunit 1-like protein 1", "WASH complex subunit 5", "WD repeat and HMG-box DNA-binding protein 1", "WD repeat-containing protein 1", "WD repeat-containing protein 82", "WNK family", "Writer", "X-ray repair cross-complementing protein 5", "X-ray repair cross-complementing protein 6", "Xaa-Pro dipeptidase", "YEATS domain-containing protein 2", "YEATS domain-containing protein 4", "YLP motif-containing protein 1", "YSK subfamily", "Zinc finger CCCH domain-containing protein 11A", "Zinc finger CCCH domain-containing protein 15", "Zinc finger CCHC domain-containing protein 8", "Zinc finger MYM-type protein 2", "Zinc finger MYM-type protein 4", "Zinc finger RNA-binding protein", "Zinc finger protein 281", "Zinc finger protein 622", "Zinc finger protein ubi-d4", "Zinc finger transcription factor", "Zinc transporter 7", "Zyxin", "[pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial", "c-Myc-binding protein", "eIF-2-alpha kinase activator GCN1", "eukaryotic two domain clade \"e\" sub-subfamily", "m7GpppX diphosphatase", "mRNA export factor", "mRNA polyadenylation factor", "mRNA processing factor", "mRNA splicing factor", "mRNA-decapping enzyme 1A", "mRNA-decapping enzyme 1B", "rRNA 2'-O-methyltransferase fibrillarin", "tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6", "tRNA (cytosine(34)-C(5))-methyltransferase", "tRNA (guanine-N(7)-)-methyltransferase", "tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4", "tRNA pseudouridine synthase A"], "available_proteins": ["AACS", "AAK1", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AATF", "ABCB1", "ABCB7", "ABCC4", "ABCD3", "ABCF1", "ABCF2", "ABCF3", "ABHD12", "ABHD6", "ACAA1", "ACAA2", "ACAD11", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGL", "AHCY", "AHCYL1", "AIFM1", "AIMP1", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKR1A1", "AKR1B1", "AKT1", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALYREF", "ANAPC1", "ANP32B", "ANP32E", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APEH", "APOBEC3C", "ARCN1", "ARFIP1", "ARFIP2", "ARHGDIA", "ARID3B", "ARIH1", "ARIH2", "ARPC1A", "ARPC1B", "ARPC3", "ARPC4", "ARVCF", "ASAH1", "ASB6", "ASH2L", "ASNA1", "ASNS", "ASRGL1", "ATAD2", "ATAD3A", "ATAD3B", "ATG3", "ATG4B", "ATIC", "ATL2", "ATL3", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP6", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "ATPAF1", "ATPIF1", "ATXN2", "ATXN2L", "AUP1", "B4GALT1", "BAG6", "BAIAP2", "BAX", "BCAP31", "BCAS2", "BCAT2", "BCLAF1", "BLMH", "BLOC1S1", "BLVRA", "BLVRB", "BOP1", "BPNT1", "BRCA1", "BRD2", "BRD4", "BRIX1", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BZW1", "BZW2", "CAB39", "CACYBP", "CAD", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAP2", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CASK", "CASP2", "CASP3", "CBL", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC88A", "CCNA2", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CDC25C", "CDC37", "CDC42", "CDC42BPB", "CDC45", "CDK1", "CDK11B", "CDK4", "CDK5", "CDK6", "CDKN2AIP", "CDX2", "CEBPZ", "CECR2", "CENPE", "CEP170", "CEP250", "CETN2", "CFAP20", "CHAF1A", "CHAF1B", "CHEK1", "CHEK2", "CHERP", "CHKA", "CHMP3", "CHMP4A", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTOP", "CHUK", "CIRBP", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLGN", "CLIC1", "CLIC4", "CLNS1A", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT3", "CNOT7", "CNP", "COASY", "COIL", "COLEC12", "COLGALT1", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS3", "COPS5", "COPS6", "COPS8", "COPZ1", "CORO1B", "CORO1C", "COTL1", "COX2", "COX5A", "COX5B", "COX7A2", "COX7A2L", "COX7C", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRNKL1", "CRTAP", "CS", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTH", "CTNNA1", "CTNND1", "CTPS1", "CTPS2", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL4B", "CUL5", "CWC22", "CYB5B", "CYB5D2", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DBN1", "DBNL", "DBT", "DCAF8", "DCP1A", "DCP1B", "DCPS", "DCTD", "DCTN1", "DCTN2", "DDB1", "DDI2", "DDOST", "DDT", "DENR", "DERL1", "DHCR24", "DHCR7", "DHFR", "DHODH", "DHX15", "DHX29", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DICER1", "DIDO1", "DIEXF", "DIS3", "DLD", "DLST", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DOLPP1", "DPF2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DSC3", "DSG2", "DSP", "DST", "DTYMK", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBP", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC4", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EGFR", "EHD1", "EHD4", "EHMT2", "EIF2A", "EIF2AK2", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3H", "EIF3I", "EIF3J", "EIF3L", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELL", "ELOB", "ELOC", "ELP1", "EMC2", "EMG1", "ENO1", "ENO2", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERC1", "ERH", "ERI1", "ERMP1", "ERO1A", "ERP29", "ESD", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC1", "EXOC3", "EXOC4", "EXOC5", "EXOC6B", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "FAHD1", "FAM177A1", "FARSB", "FASN", "FBL", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FKBP1A", "FKBP4", "FKBP5", "FMR1", "FNTA", "FNTB", "FOXRED1", "FSCN1", "FUBP1", "FUBP3", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBE1", "GCAT", "GCFC2", "GCLM", "GCN1", "GDI1", "GDI2", "GFPT1", "GGH", "GGT7", "GID8", "GLB1", "GLDC", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNE", "GNG5", "GNPDA1", "GNS", "GOLGA2", "GPATCH4", "GPD2", "GPI", "GPKOW", "GPN1", "GPR107", "GPR89B", "GPT2", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GTF2B", "GTF2F1", "GTF2F2", "GTF3C3", "GTF3C5", "GTPBP1", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADHA", "HADHB", "HARS2", "HAT1", "HBS1L", "HCCS", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HEATR1", "HEATR6", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HM13", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGN1", "HMGN2", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HPRT1", "HSD17B10", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HTATSF1", "HUWE1", "IARS", "IARS2", "IDE", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFNGR1", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBKB", "IKBKG", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPA1", "IMPAD1", "IMPDH1", "IMPDH2", "INTS11", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "ITCH", "ITGB1", "ITPA", "ITSN2", "IVD", "JMJD6", "KARS", "KAT7", "KCTD12", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KHDRBS1", "KHDRBS3", "KHSRP", "KIF11", "KIF14", "KIF15", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIFC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRR1", "L2HGDH", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS2", "LBR", "LDHA", "LDHB", "LDLRAP1", "LETM1", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LNPEP", "LONP1", "LPCAT1", "LRRC47", "LRWD1", "LSM14A", "LSM14B", "LSM2", "LSM6", "LTN1", "M6PR", "MACF1", "MAGED1", "MAGED2", "MAGT1", "MAN1A2", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K3", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCH5", "MARK1", "MARK2", "MAT2A", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MDH1", "MDH2", "ME2", "MECP2", "MED14", "MED21", "METAP1", "METTL1", "MFAP1", "MFN1", "MFN2", "MFSD5", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MIPEP", "MKRN2", "MMS19", "MOB4", "MORF4L1", "MPC2", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRPL1", "MRPL11", "MRPL12", "MRPL14", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL22", "MRPL23", "MRPL39", "MRPL43", "MRPL44", "MRPL47", "MRPL9", "MRPS11", "MRPS16", "MRPS18A", "MRPS2", "MRPS27", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR2", "MTOR", "MTPAP", "MTSS1L", "MUT", "MVK", "MYBBP1A", "MYCBP", "MYEF2", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA16", "NAA35", "NAA50", "NADK2", "NAE1", "NAGK", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NBN", "NCAPD2", "NCBP1", "NCL", "NCOA5", "NCOR1", "ND5", "NDC80", "NDRG3", "NDUFA10", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA8", "NDUFA9", "NDUFB1", "NDUFB11", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS6", "NDUFS7", "NDUFS8", "NEK9", "NFKB1", "NFS1", "NHP2", "NIPBL", "NISCH", "NKRF", "NLN", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOC4L", "NOL6", "NOM1", "NONO", "NOP14", "NOP56", "NOP58", "NOP9", "NOVA1", "NPEPPS", "NPM1", "NPTN", "NRBP1", "NRDC", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSUN2", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP107", "NUP153", "NUP160", "NUP210", "NUP214", "NUP37", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "OAT", "OCIAD1", "OCRL", "OLA1", "OPA1", "ORC3", "ORC5", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "PACSIN2", "PACSIN3", "PAICS", "PAIP1", "PAK1", "PAK2", "PAK4", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PDCD11", "PDCD5", "PDCD6IP", "PDE12", "PDE6D", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXK", "PEBP1", "PECR", "PELO", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PGD", "PGGT1B", "PGK1", "PGLS", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHF10", "PHF3", "PHF6", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGK", "PIK3C2A", "PIK3C3", "PIK3R4", "PINX1", "PIP4K2B", "PIR", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCB3", "PLCG1", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMS1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POGZ", "POLA2", "POLD2", "POLDIP3", "POLE2", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "PPA1", "PPA2", "PPAT", "PPIL1", "PPIL3", "PPM1G", "PPME1", "PPP1CA", "PPP1CB", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP4R1", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX6", "PREB", "PREP", "PRIM1", "PRKAA1", "PRKAA2", "PRKACA", "PRKAG1", "PRKCD", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRPF3", "PRPF31", "PRPF39", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC2A", "PRRC2B", "PRRC2C", "PSIP1", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSMF1", "PSPC1", "PSPH", "PTCD1", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN9", "PTPRF", "PUM1", "PURA", "PUS1", "PWP1", "PXMP2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "QSOX2", "RAB3GAP2", "RABGAP1", "RABGGTA", "RABGGTB", "RAC1", "RACGAP1", "RAD23A", "RAD23B", "RAE1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAPGEF2", "RAPGEF6", "RAVER1", "RBBP6", "RBM12", "RBM12B", "RBM14", "RBM17", "RBM19", "RBM22", "RBM26", "RBM27", "RBM3", "RBM4", "RBMX", "RBPMS", "RCL1", "RCN1", "RCN2", "RDH11", "RDH14", "RDX", "RECQL", "RECQL4", "RECQL5", "REEP3", "REEP4", "REEP5", "REPS1", "RFC2", "RFC3", "RFC4", "RFC5", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIPK1", "RNASEH2A", "RNF14", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAS2", "RRM1", "RRM2", "RRM2B", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RTCA", "S100A10", "S100A11", "S100A13", "SAE1", "SAP18", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SBNO1", "SCAF4", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCFD1", "SCML2", "SCO1", "SCO2", "SCPEP1", "SCYL2", "SDCBP", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC23A", "SEC23IP", "SEC24A", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEH1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD7", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B3", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SHMT1", "SHMT2", "SIN3A", "SIRT1", "SKP1", "SLC12A2", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A5", "SLC25A6", "SLC27A4", "SLC30A7", "SLC35B2", "SLC35F2", "SLC38A2", "SLC3A2", "SLC6A15", "SLK", "SLU7", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMN1*", "SNAP23", "SNAP29", "SND1", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SOAT1", "SOD2", "SORD", "SORT1", "SPAG9", "SPCS2", "SPHK2", "SPNS1", "SPPL2A", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SREK1", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRRM1", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "STAG1", "STAG2", "STAMBP", "STAT1", "STAT3", "STK26", "STK4", "STOM", "STOML2", "STRBP", "STT3A", "STT3B", "STX12", "STX18", "STX4", "STX6", "STX7", "STX8", "STXBP2", "STXBP3", "SUCLA2", "SUCLG2", "SUGP1", "SUGP2", "SUN1", "SUN2", "SUPT16H", "SUPT6H", "SURF6", "SUZ12", "SYNCRIP", "SYNGR2", "SYNJ2BP", "TAB1", "TAF15", "TAGLN2", "TAP1", "TARS", "TARS2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D17", "TBC1D2B", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCA", "TBCB", "TBCC", "TBCD", "TBCE", "TBK1", "TCEA1", "TCERG1", "TCP1", "TCP11L1", "TDRD7", "TDRKH", "TECR", "TES", "TFCP2", "TFIP11", "TFRC", "THOC1", "THOC2", "THOC3", "THOP1", "THRAP3", "TJP1", "TJP2", "TK1", "TKT", "TM9SF2", "TM9SF3", "TM9SF4", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM165", "TMEM97", "TMOD1", "TMOD3", "TMPO", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM40", "TOP1", "TOR1B", "TP53", "TP53BP1", "TPBG", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAP1", "TRAPPC4", "TRIO", "TRMT6", "TROVE2", "TRUB1", "TSC2", "TSFM", "TSG101", "TSPYL1", "TTC28", "TTK", "TTYH3", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXN2", "TXNDC12", "TXNDC17", "TXNDC9", "TXNRD1", "TYMS", "U2AF1", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBE2L3", "UBE4A", "UBP1", "UCHL5", "UCK2", "UGCG", "UGGT1", "UNC119B", "UPF1", "UPF2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "USO1", "USP10", "USP11", "USP14", "USP15", "USP28", "USP39", "USP47", "USP5", "USP7", "UTP11", "UTP14A", "UTP6", "VAC14", "VAMP7", "VAPA", "VAPB", "VBP1", "VKORC1L1", "VPS18", "VPS26A", "VPS26B", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS4B", "VRK1", "VRK2", "VTI1B", "WARS", "WASHC5", "WASL", "WDHD1", "WDR1", "WDR4", "WDR82", "WIZ", "WNK1", "WNK2", "XAB2", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "YAP1", "YARS", "YARS2", "YEATS2", "YEATS4", "YLPM1", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H15", "ZCCHC11", "ZCCHC8", "ZFR", "ZMPSTE24", "ZMYM2", "ZMYM4", "ZNF281", "ZNF598", "ZNF622", "ZW10", "ZYX"], "leading_proteins": ["ABHD12", "ACAT2", "ACOX1", "ACP6", "AIFM1", "AP3M1", "APOBEC3C", "ASAH1", "ATP1A1", "ATP1B1", "ATP2A2", "ATP2B1", "ATP6", "ATP6V0A1", "ATP6V0A2", "BAIAP2", "BUB1B", "BUD31", "CARM1", "CASP3", "CBX3", "CBX5", "CDK5", "CHUK", "CIRBP", "CLCC1", "CLUH", "COMT", "COMTD1", "COPS5", "COX5A", "COX7A2", "CPVL", "CRTAP", "CTCF", "CTPS1", "CTPS2", "CTSA", "CTSB", "CYB5B", "CYB5D2", "CYP51A1", "DCAF8", "DHCR24", "DHCR7", "DHFR", "DPP9", "DVL2", "EBP", "ECE1", "EIF4E", "ERAP1", "ERMP1", "EWSR1", "FKBP1A", "FKBP4", "FNTB", "FOXRED1", "FUBP1", "FUS", "GAA", "GFPT1", "GGH", "GGT7", "GM2A", "GPR89B", "HDGF", "HINT3", "HK1", "HNRNPK", "HSP90AA1", "HSP90AB1", "HSP90B1", "IKBKB", "IPO7", "KDELR1", "KDELR3", "KDM1B", "KHDRBS3", "KHSRP", "LAMC1", "LBR", "LDLRAP1", "LMAN1", "LNPEP", "LSM6", "MAPK1", "MFN2", "MIA2", "MIPEP", "MPC2", "MPV17L2", "MSMO1", "MTCH2", "NAMPT", "NAP1L4", "NDUFB1", "NDUFB4", "NDUFS2", "NLN", "NPEPPS", "NPTN", "NSUN2", "NT5C3A", "NT5C3B", "NT5DC1", "NTMT1", "NUCB1", "NUCB2", "OLA1", "OPA1", "OTUB1", "OXA1L", "P3H1", "P3H4", "PAK2", "PCMT1", "PEBP1", "PECR", "PGGT1B", "PGRMC1", "PGRMC2", "PI4KA", "PI4KB", "PIR", "PITRM1", "PLA2G15", "PLBD2", "POGZ", "PPAT", "PPP2R1A", "PPP2R1B", "PPT1", "PPT2", "PRCP", "PRDX3", "PREP", "PRKAA2", "PRMT1", "PRMT5", "PXMP2", "RALA", "RAVER1", "RBM14", "RBM3", "RBM4", "RBMX", "RBPMS", "REEP3", "RRM2B", "SCARB1", "SCARB2", "SCO1", "SCPEP1", "SEC11A", "SET", "SF3A2", "SHMT1", "SHMT2", "SLC16A1", "SLC18B1", "SLC19A1", "SLC25A10", "SLC25A11", "SLC25A15", "SLC25A20", "SLC25A26", "SLC25A32", "SLC25A33", "SLC25A4", "SLC35F2", "SLC38A2", "SLU7", "SNAP29", "SORT1", "SPPL2A", "SRPK2", "SRSF9", "SSR1", "STAMBP", "STX18", "STX6", "TAF15", "TAP1", "TBC1D10A", "TBC1D15", "TBC1D17", "TBC1D4", "TBC1D8B", "TBC1D9B", "TCP11L1", "TECR", "TFRC", "TM9SF2", "TM9SF3", "TMED2", "TMED9", "TMEM165", "TMEM97", "TNPO1", "TRA2B", "TXNDC12", "UNC119B", "UQCR10", "USP15", "USP47", "VKORC1L1", "VPS18", "WIZ", "XPO5", "YME1L1", "ZADH2", "ZC3H15", "ZMPSTE24"]} \ No newline at end of file diff --git a/pharos_protein_category/advanced/idx2term.json b/pharos_protein_category/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..6e0847ffc649d08286e63465c7dfff7898d31ecd --- /dev/null +++ b/pharos_protein_category/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Tbio"} \ No newline at end of file diff --git a/pharos_protein_category/advanced/plot_0.png b/pharos_protein_category/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..8166d3b6c09fe6c86b84ea4e2c4a404fbbe1305c --- /dev/null +++ b/pharos_protein_category/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:84d53a4acd996681a6c88982cc71531e4690daa0d7137616e44c2681150f6a4d +size 214396 diff --git a/pharos_protein_category/basic/idx2term.json b/pharos_protein_category/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..ac8cf61ab14dc2273eaa55f68f9d4cb4293c3b20 --- /dev/null +++ b/pharos_protein_category/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Tbio", "1": "Tclin", "2": "Tchem"} \ No newline at end of file diff --git a/pharos_protein_category/basic/plot_0.png b/pharos_protein_category/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..4c80f5e3f1dc7cab7ecc62cffe15984d3a7b8e27 --- /dev/null +++ b/pharos_protein_category/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:369d3a24bac591c68e0f4d2d42635c61668444d3e60b551845c47dace7233960 +size 130219 diff --git a/pharos_protein_category/basic/plot_1.png b/pharos_protein_category/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..b6d8b0ec7b3259297097f55407c02384f55e43ed --- /dev/null +++ b/pharos_protein_category/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9fcea85337b24724208414915393ab313ada7c4dc77de71054300442e06d28f5 +size 132781 diff --git a/pharos_protein_category/basic/plot_2.png b/pharos_protein_category/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..589d9085188cab36e075a27652b6c5626e62138c --- /dev/null +++ b/pharos_protein_category/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a44bfafc84b7639b44b236b810acdc326a5c4454811493e5cf9e5fc1433c0c99 +size 136505 diff --git a/pharos_protein_category/consensus.joblib b/pharos_protein_category/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..c9fa4695a3ff2815d8501276ba2588ef87e9dde1 --- /dev/null +++ b/pharos_protein_category/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c78e3a2f795d1ed25b45d44b9ad5113ddd5aba2fe68822914a06a8db17711e8f +size 82126 diff --git a/pharos_protein_category/df_merge.tsv b/pharos_protein_category/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..aceddfaf7605e035714fecefae166a6573b6f98e --- /dev/null +++ b/pharos_protein_category/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Tbio 306 2552 8.94452147063308 3.735647470988785e-19 467.6796116504854 2434.25 -0.5416405556668178 0.3215141878443288 119.73666199244032 234.70955636597876 4.704421961664106 0.4116627836259234 0.9950562573537348 0.8740671349221033 0.999715815647188 0.9252780892843157 0.4163955050983974 diff --git a/pharos_protein_category/metrics.json b/pharos_protein_category/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..0470c61e25e0492a89f82692758553d92bfcde1f --- /dev/null +++ b/pharos_protein_category/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3329, + "annotations_size": 4, + "title": "Average number of proteins per term", + "value": 832.0 +} \ No newline at end of file diff --git a/pharos_protein_category/paths.json b/pharos_protein_category/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..e233106e5599aed18660253ce20ccd0c708b0096 --- /dev/null +++ b/pharos_protein_category/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_protein_category/fragment/C342/C342_val_log2fc"} \ No newline at end of file diff --git a/pharos_protein_category/result.tsv b/pharos_protein_category/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..42e293071b93f82fc400277b754a655014411bac --- /dev/null +++ b/pharos_protein_category/result.tsv @@ -0,0 +1,4 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Tbio 0.1709997092646219 8.94452147063308 3.735647470988785e-19 5.494258988395514e-18 5.494258988395514e-18 2552 O15217,Q16740,Q8N4Q0,Q9BV86,Q96PZ0,Q9NPH0,Q15392,Q9NS69,O94888,Q96AY3,A6NIH7,P00846,O60888,Q14739,Q70HW3,Q7RTS9,Q567V2,P24390,O75153,Q9NTK5,Q96DY7,P26885,Q99595,O00625,Q32P28,Q9UMX5,Q9Y619,Q96FW1,O43772,Q9NUJ1,P80303,Q8N4Q1,P30086,Q9BWD1,O75503,Q86UY6,P28072,O43169,P21796,P19474,Q9BSK2,Q9H2D1,Q9UQB8,Q8TCT8,Q9HB40,Q8NCC3,P35270,Q9H3G5,O95563,Q9Y639,Q9Y282,Q9UQ84,P46379,Q9NR28,Q92804,Q16799,O95831,Q02978,Q86XL3,Q9UM22,Q03518,O00461,O43657,Q9UHG3,O15173,Q15363,P98179,Q14168,P43307,Q53HL2,Q96A26,Q9NVH6,P35637,P50897,Q8TAE8,P28070,P53701,Q9UJ14,Q9Y2R0,O75844,O95197,P30154,Q16836,Q9BXS4,Q96CU9,Q15067,Q8NCH0,P07602,Q06136,P30153,Q9Y487,Q14257,Q9BQG2,Q9H6W3,Q9Y5A9,Q9UMY4,Q14108,O14949,O95373,Q07065,Q8IZA0,Q93050,Q96G23,Q92791,Q9Y680,Q8IWV7,O43505,P17812,Q15800,P55010,Q9UDW1,Q9UMR5,O95400,Q96DG6,Q9H0P0,O43347,Q9NWM8,P31942,O43909,Q6DKK2,O43752,P51530,Q7LG56,P31943,Q15070,Q15041,O75525,P22626,Q14011,Q969T9,Q9H6K4,P34896,O14979,Q9NYY8,Q9BRR6,Q9H2J4,Q9NZ01,P49257,Q9UDX5,Q9HC07,O60313,P35613,O60343,Q15165,Q9NRW3,P51116,Q9P2W9,Q7KZ85,O95391,P46108,Q01844,P09493,P54725,P38159,O14925,Q6PGP7,Q8N0U8,Q9BTX1,Q9BUJ2,Q9UJX3,Q96JB2,Q8NB78,O95140,O15460,O75976,O95674,Q9H061,Q92614,P11047,Q9NSE4,P12235,P55795,Q01105,Q8IV08,Q9NQ11,P53365,P34897,P16989,Q96AE4,Q9UJX6,Q9P253,Q9NZW5,Q9H6D7,Q96S66,Q9BY49,Q92973,Q15007,O95684,O60506,O60244,O43823,Q86YV9,Q96L92,Q9BUK6,P18085,P10321,P60900,P98175,Q14181,Q9BRF8,Q92733,Q5VV42,P07196,O95881,O43390,Q9UHX1,Q99729,Q96PK6,O95721,P67809,O75880,P51114,O60925,Q8N511,P62857,Q9Y5P6,Q9HAV4,Q8NI60,Q6DKJ4,Q5VZE5,P62995,P11233,Q99733,P67812,P52597,Q969V3,O75718,O60566,Q9NRV9,Q9Y5S2,Q9UBS8,Q9BYT8,P53611,P84085,Q9NQZ5,Q8NBX0,Q6PJG6,Q5XKP0,Q01081,P51991,O15027,O14641,P20674,Q15555,Q96QD8,Q8IZL8,Q5T8D3,P0CG13,P20645,O95456,O95429,O14737,P04083,Q6P4A7,Q9H3K2,Q8N5M9,P08670,Q16352,Q9Y6C9,Q9BRP8,Q7Z739,Q9BU89,Q13576,O96005,O75151,Q04837,Q9UBX3,Q9P035,Q92945,Q9Y2S7,Q8NHP8,Q5T6F2,P51648,O43852,O15118,O15360,O15397,Q14103,Q16134,Q9UBG0,Q96FZ2,Q8NFF5,Q06787,Q9NRF8,Q9Y6Y8,Q68CZ6,P49643,P67936,A1L0T0,P17900,O75648,P61978,Q92783,Q9Y262,Q9UBK9,Q9H4L5,Q7LGA3,Q14914,Q6P2P2,Q9Y5X3,Q9Y237,Q9H900,Q9BXI6,Q92734,Q8NBT2,Q8N2F6 306 +Tclin 0.4082789914732755 1.5009631885818064 0.1333650829873807 0.4359147656181273 0.2667301659747614 93 P62942,Q16739,P25786,P28074,O75438,O95168,P48735,O43676,P00374,P20618,P21964,P49721,Q99720,Q9Y6M9,Q9Y2I1,Q06203,P38435,O75306,O43924,Q86Y39 20 +Tchem 0.3816850011671771 0.6372358391350736 0.5239712363563211 0.94865090644308 0.6986283151417615 330 Q9H773,P43490,P37268,Q99523,P30519,Q9UIQ6,Q8WTV0,P42785,Q5BJF2,P35790,O60502,P09601,Q13451,P41440,O60725,P48147,P04062,Q16850,P45880,P78417,P48449,Q02818,P13674,P23786,O75874,P31749,P42892,Q02790,Q13126,P30536,Q9NZ08,P10619,O95470,P42356,O15270,Q8N2K0,P07099,Q15125,Q9UBM7,Q9BTY2,P49356,P55786,P06730,P53609,Q15120,Q5JRX3 46 diff --git a/pharos_protein_category/selections.json b/pharos_protein_category/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..fa394cefbd894bf4690e34c56ce8784a076e667d --- /dev/null +++ b/pharos_protein_category/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Tbio", "Tchem", "Tclin", "Tdark"], "available_proteins": ["AAAS", "AACS", "AAGAB", "AAK1", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD11", "ABHD12", "ABHD14B", "ABHD6", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ADA", "ADAM17", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKT1", "AKT1S1", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG13", "ALG5", "ALKBH1", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APC", "APEH", "APEX1", "API5", "APMAP", "APOBEC3C", "APOO", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP3", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGAP35", "ARHGAP5", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL6IP5", "ARL8B", "ARMC1", "ARMC10", "ARMC6", "ARMC9", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARVCF", "ASAH1", "ASB6", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATE1", "ATF7IP", "ATG3", "ATG4B", "ATG9A", "ATIC", "ATL2", "ATL3", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATRX", "ATXN10", "ATXN2", "ATXN2L", "AUP1", "B3GALT6", "B4GALT1", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BCAP31", "BCAS2", "BCAT2", "BCCIP", "BCL2L12", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BDH2", "BICD2", "BIRC6", "BLM", "BLMH", "BLOC1S1", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOD1L1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAP", "BRAT1", "BRCA1", "BRD2", "BRD4", "BRI3BP", "BRIX1", "BROX", "BSG", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C12orf73", "C14orf2", "C15orf39", "C19orf25", "C19orf70", "C1QBP", "C1orf122", "C1orf123", "C1orf35", "C1orf50", "C20orf27", "C21orf59", "C2CD5", "C2orf49", "C5orf15", "C5orf51", "CAB39", "CACTIN", "CACUL1", "CACYBP", "CAD", "CADM1", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAP2", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CASK", "CASP2", "CASP3", "CAST", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC124", "CCDC138", "CCDC22", "CCDC43", "CCDC47", "CCDC51", "CCDC6", "CCDC86", "CCDC88A", "CCDC93", "CCDC94", "CCDC97", "CCNA2", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC23", "CDC25C", "CDC27", "CDC37", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP3", "CDK6", "CDKAL1", "CDKN2A", "CDKN2AIP", "CDR2L", "CDS2", "CDV3", "CDX2", "CEBPZ", "CECR2", "CELF1", "CENPB", "CENPE", "CENPI", "CENPU", "CENPV", "CEP170", "CEP250", "CEP44", "CEP55", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHCHD4", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP4A", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHP1", "CHRAC1", "CHST14", "CHTF18", "CHTF8", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLN6", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTA", "CLTC", "CLU", "CLUH", "CMAS", "CMBL", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNOT1", "CNOT11", "CNOT3", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG2", "COG3", "COG4", "COG7", "COIL", "COLEC12", "COLGALT1", "COMMD1", "COMMD10", "COMMD2", "COMMD7", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "CORO1B", "CORO1C", "COTL1", "COX11", "COX15", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTDSPL2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CTTNBP2NL", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC22", "CWF19L1", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF7", "DCAF8", "DCAKD", "DCD", "DCP1A", "DCP1B", "DCP2", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENND4C", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHODH", "DHPS", "DHRS1", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DIS3L2", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTL", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFL1", "EFTUD2", "EGFR", "EGLN1", "EHBP1", "EHD1", "EHD4", "EHMT2", "EIF2A", "EIF2AK2", "EIF2AK4", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP4", "EMC1", "EMC2", "EMC3", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENSA", "EPB41", "EPB41L2", "EPB41L5", "EPDR1", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6B", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXTL3", "EZR", "F11R", "FABP5", "FAF1", "FAF2", "FAH", "FAHD1", "FAM114A1", "FAM114A2", "FAM118B", "FAM160A2", "FAM162A", "FAM177A1", "FAM208A", "FAM213A", "FAM49B", "FAM50A", "FAM83D", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FAU", "FBL", "FBXO22", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNBP4", "FNDC3A", "FNTA", "FNTB", "FOXRED1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLM", "GCN1", "GDAP1", "GDAP2", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GEMIN8", "GET4", "GFM1", "GFPT1", "GGA1", "GGCT", "GGCX", "GGH", "GGT7", "GHDC", "GHITM", "GID4", "GID8", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNE", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM1", "GOLPH3", "GOLPH3L", "GOLT1B", "GOPC", "GORASP2", "GOT1", "GOT2", "GPAM", "GPATCH4", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR108", "GPR89B", "GPS1", "GPSM1", "GPT2", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSDME", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTSE1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAGH", "HARS2", "HAT1", "HAUS1", "HAUS2", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HELLS", "HERC4", "HEXA", "HEXB", "HEXIM1", "HGH1", "HGS", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIP1", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOXD13", "HP1BP3", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA6", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HUS1", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IER3IP1", "IFIT5", "IFNGR1", "IFT27", "IFT88", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "IKBKB", "IKBKG", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPA1", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS11", "INTS12", "INTS13", "INTS14", "INTS3", "INTS7", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRGQ", "IRS4", "ISCU", "ISG20L2", "ISOC1", "ISOC2", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITSN2", "IVD", "IWS1", "JAGN1", "JMJD6", "JPT2", "JUP", "KARS", "KAT7", "KCTD12", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1211", "KIAA1468", "KIAA2013", "KIF11", "KIF14", "KIF15", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "L2HGDH", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCMT1", "LDHA", "LDHB", "LDLR", "LDLRAP1", "LEMD2", "LEMD3", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRCH2", "LRP1", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRWD1", "LSM12", "LSM14A", "LSM14B", "LSM2", "LSM6", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYPLAL1", "LZIC", "LZTFL1", "LZTS2", "M6PR", "MACF1", "MAD1L1", "MAGED1", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K3", "MAP4", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARK1", "MARK2", "MARS", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MEAF6", "MECP2", "MED1", "MED14", "MED16", "MED21", "MED23", "MED24", "MED4", "MEPCE", "METAP1", "METAP2", "METTL1", "METTL13", "METTL16", "METTL3", "MFAP1", "MFF", "MFN1", "MFN2", "MFSD10", "MFSD5", "MGAT1", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MICALL1", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MKLN1", "MKRN2", "MLEC", "MMAB", "MMGT1", "MMS19", "MOB4", "MOGS", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRC2", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL22", "MRPL23", "MRPL28", "MRPL3", "MRPL37", "MRPL39", "MRPL4", "MRPL40", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL50", "MRPL55", "MRPL58", "MRPL9", "MRPS10", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTERF3", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR2", "MTOR", "MTPAP", "MTR", "MTSS1L", "MTX1", "MTX2", "MTX3", "MUT", "MVK", "MXRA7", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA16", "NAA35", "NAA40", "NAA50", "NACC1", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCDN", "NCKAP1", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "ND5", "NDC1", "NDC80", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEFL", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NFATC2IP", "NFKB1", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NMD3", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NRDE2", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSUN2", "NSUN5", "NSUN6", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUB1", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PATL1", "PAXIP1", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNP", "PCNT", "PCYOX1", "PDAP1", "PDCD11", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXDC1", "PDXK", "PDZD8", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN1", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGGT1B", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF2", "PHF3", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PI4KB", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIH1D1", "PIK3C2A", "PIK3C3", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2B", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCB3", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNISR", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPO", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPFIA1", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKAR2B", "PRKCD", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF39", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN23", "PTPN9", "PTPRF", "PTRH2", "PTRHD1", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "PYM1", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABEP1", "RABEPK", "RABGAP1", "RABGGTA", "RABGGTB", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RANGRF", "RAP1GDS1", "RAPGEF2", "RAPGEF6", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM47", "RBM5", "RBM8A", "RBMX", "RBPMS", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "RECQL5", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "RETREG3", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOX1", "RIOX2", "RIPK1", "RMDN1", "RMND5A", "RNASEH2A", "RNASEH2B", "RNASET2", "RNF14", "RNF20", "RNF219", "RNF220", "RNF40", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RPUSD2", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCA", "RTCB", "RTF1", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SAAL1", "SACM1L", "SACS", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SASS6", "SBDS", "SBNO1", "SCAF1", "SCAF11", "SCAF4", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCYL2", "SDAD1", "SDCBP", "SDF2L1", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD7", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL", "SH3BGRL2", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIN3A", "SIRT1", "SKA1", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A5", "SLC25A6", "SLC27A4", "SLC30A7", "SLC35A4", "SLC35B2", "SLC35F2", "SLC38A2", "SLC3A2", "SLC4A1AP", "SLC6A15", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SLU7", "SMAP1", "SMAP2", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC6", "SMCHD1", "SMG8", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SNAP23", "SNAP29", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC24", "SPC25", "SPCS2", "SPDL1", "SPECC1", "SPECC1L", "SPEN", "SPHK2", "SPNS1", "SPOUT1", "SPPL2A", "SPR", "SPRYD4", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRBD1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX4", "STX6", "STX7", "STX8", "STXBP2", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE1", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACC3", "TACO1", "TADA3", "TAF15", "TAGLN2", "TALDO1", "TAMM41", "TANGO6", "TAP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D17", "TBC1D2B", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCA", "TBCB", "TBCC", "TBCD", "TBCE", "TBK1", "TBL1XR1", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TCP11L1", "TDRD7", "TDRKH", "TECR", "TELO2", "TERF2", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGS1", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM17A", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TIMM9", "TIMMDC1", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLN1", "TM9SF2", "TM9SF3", "TM9SF4", "TMA16", "TMA7", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM11", "TMEM126A", "TMEM126B", "TMEM160", "TMEM165", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM206", "TMEM209", "TMEM214", "TMEM230", "TMEM245", "TMEM30A", "TMEM33", "TMEM43", "TMEM59", "TMEM63A", "TMEM87A", "TMEM97", "TMF1", "TMLHE", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOM1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPMT", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIO", "TRIP12", "TRIP13", "TRIR", "TRMT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMU", "TROVE2", "TRUB1", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN10", "TSPAN3", "TSPAN6", "TSPO", "TSPYL1", "TSR1", "TSR2", "TTC1", "TTC19", "TTC26", "TTC27", "TTC28", "TTC37", "TTC38", "TTC4", "TTF2", "TTI1", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXN2", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAP2", "UBAP2L", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE2T", "UBE3A", "UBE3C", "UBE4A", "UBL5", "UBLCP1", "UBP1", "UBQLN1", "UBQLN2", "UBQLN4", "UBR1", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "UHRF1BP1", "UMPS", "UNC119B", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "UROD", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP15", "USP24", "USP28", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "UXT", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VPS13A", "VPS18", "VPS25", "VPS26A", "VPS26B", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37C", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK2", "VTA1", "VTI1B", "WAPL", "WARS", "WARS2", "WASHC3", "WASHC5", "WASL", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR36", "WDR4", "WDR41", "WDR43", "WDR45B", "WDR46", "WDR48", "WDR5", "WDR6", "WDR61", "WDR70", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WNK1", "WNK2", "WRAP53", "WRAP73", "WTAP", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YAP1", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YEATS4", "YIF1A", "YIPF4", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF1", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM2", "ZMYM4", "ZMYND8", "ZNF24", "ZNF281", "ZNF318", "ZNF326", "ZNF512B", "ZNF598", "ZNF622", "ZNF638", "ZPR1", "ZRANB2", "ZSWIM8", "ZW10", "ZWILCH", "ZYX"], "leading_proteins": ["ABHD10", "ABHD12", "ACAT2", "ACBD5", "ACOX1", "ACP6", "ADPGK", "AIFM1", "AKAP8", "AKT1", "ALDH3A2", "ANAPC2", "ANAPC7", "ANKLE2", "ANXA1", "APOBEC3C", "ARF4", "ARF5", "ARFIP2", "ARL6IP1", "ARMC10", "ATP13A2", "ATP6", "ATP6V0A1", "ATP6V0A2", "B4GAT1", "BAG4", "BAG6", "BAIAP2", "BRAT1", "BSG", "BUB1B", "C19orf70", "CALU", "CD2BP2", "CDC42BPB", "CDCA8", "CDKAL1", "CDS2", "CERS2", "CHCHD4", "CHKA", "CHST14", "CHTF8", "CIRBP", "CKAP4", "CLCC1", "CLN5", "CLPP", "CLPTM1", "CLUH", "CMBL", "COA3", "COG3", "COMT", "COQ8A", "COX5A", "CPD", "CPPED1", "CPT2", "CPVL", "CRK", "CRTAP", "CTPS1", "CTPS2", "CTSA", "CUTA", "CYB5B", "CYP51A1", "DCTPP1", "DHCR24", "DHCR7", "DHFR", "DIABLO", "DNA2", "DOHH", "DVL2", "DYM", "EBP", "ECE1", "EIF3L", "EIF4E", "EIF5", "EPDR1", "EPHX1", "ERAP1", "ERGIC3", "ETFDH", "EWSR1", "EXO1", "EXTL3", "FAM162A", "FANCA", "FASTKD2", "FDFT1", "FGFR1OP", "FKBP10", "FKBP14", "FKBP1A", "FKBP2", "FKBP4", "FKBP5", "FKBP7", "FLAD1", "FMR1", "FNTB", "FOXRED1", "FUBP1", "FUCA2", "FUS", "FXR1", "FXR2", "GADD45GIP1", "GBA", "GGCX", "GGT7", "GHITM", "GM2A", "GMPPB", "GOLIM4", "GSTA4", "GSTO1", "HACD3", "HADH", "HAUS3", "HAUS4", "HCCS", "HEBP1", "HLA-C", "HMCES", "HMOX1", "HMOX2", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPR", "HNRNPUL1", "HPS6", "HS2ST1", "IARS2", "ICMT", "IDH1", "IDH2", "ILVBL", "INA", "IPO7", "IPO8", "IQGAP2", "JAGN1", "KDELR1", "KDM1B", "KDSR", "KHDRBS3", "KHSRP", "KIAA0319L", "LAMC1", "LBR", "LMAN1", "LNPEP", "LSS", "M6PR", "MAPRE2", "MED14", "MFN2", "MGEA5", "MPC2", "MPP2", "MPP6", "MPV17L2", "MRC2", "MSI1", "MSMO1", "MSTO1", "MTAP", "MTBP", "MTCH2", "MTFP1", "MYO18A", "NAA35", "NAA40", "NAMPT", "NAP1L4", "NCLN", "NDC1", "NDUFA11", "NDUFB1", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS2", "NEFL", "NENF", "NISCH", "NLN", "NPC1", "NPEPPS", "NPTN", "NT5C3A", "NTMT1", "NUCB1", "NUCB2", "NUDT12", "NXN", "OLA1", "OPA1", "OPA3", "OSBPL3", "OTUB1", "OXA1L", "P3H1", "P3H4", "P4HA1", "P4HA2", "PCYOX1", "PDCD5", "PDCL3", "PDE6D", "PDK3", "PEBP1", "PECR", "PELP1", "PFDN1", "PGGT1B", "PGRMC2", "PHF2", "PI4KA", "PIN4", "PIR", "PITRM1", "PLA2G15", "PLBD2", "PLD3", "POLA2", "POLDIP2", "PON2", "PPAT", "PPP2R1A", "PPP2R1B", "PPT1", "PPT2", "PRCC", "PRCP", "PREP", "PRIM2", "PRMT9", "PSAP", "PSMA1", "PSMA6", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMG1", "PTGR1", "PUF60", "PUS7", "PYM1", "RABGGTB", "RAD23A", "RALA", "RBM10", "RBM14", "RBM3", 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15.854368932038836 1.2489526119817105 0.2730082640054638 2.2746228138386324 2.237837752303934 0.9571049414552286 0.2704007779320353 0.0006671136126396 0.0001600370606554 0.0011959433226113 5.778158844146178e-07 5.709112060691291e-05 +Cholesterol biosynthesis 6 16 2.698762651199579 0.0069597793878004 4.478155339805825 14.449029126213592 1.241205081084055 0.2669045154832569 1.9237928998467095 1.7749125587996368 0.9260618360685376 0.2641298712278396 0.0004270336690734 0.0001017478453213 0.0007685743700876 1.8173396906145925e-07 1.9173699754060086e-05 +Cholesterol metabolism 7 27 2.638189455075412 0.0083350001755577 7.111650485436893 23.79854368932039 1.169709264926864 0.2871268807807383 2.8890755390042298 2.7173834172675666 1.205315163774447 0.3061468445376054 0.0053915705605471 0.0013622028220488 0.0093807730237194 1.0827347520172698e-05 0.0002699095083601 +Sterol metabolism 7 27 2.638189455075412 0.0083350001755577 7.606796116504855 25.203883495145632 1.1785484151208083 0.2872927387372206 3.1377365577760563 3.096691699470945 1.2399567569518877 0.3064799172119154 0.0064607496534732 0.0016433207319013 0.0111977735740575 1.7797131365174685e-05 0.000448399296129 +Transport 88 510 2.5957336388407124 0.0094389205920413 127.39320388349516 491.7621359223301 1.4832290368286314 0.5289485259644714 40.31460927260851 50.077723312236 2.248556521823017 0.4543981544818752 0.0008478752752058 0.0617401122425239 0.0008981676060948 1.7776668471310024e-05 6.889512655095435e-07 +Sphingolipid metabolism 8 10 2.557532316482299 0.0105417762451462 5.075242718446602 9.720873786407768 1.0723891387155546 0.1672146303539832 2.245095774833478 1.0461446620678432 1.744521381224598 0.248179764200939 1.0 1.0 0.1693528922958147 4.054377957418495e-06 8.775199022935695e-08 +Steroid metabolism 7 28 2.5282092797575006 0.0114645990516935 7.703883495145631 26.439320388349515 1.128083592407629 0.3052190273048834 3.279782799169419 3.1412859163137186 1.216134343451914 0.3162944576553002 0.009418704937411 0.0024333620388206 0.0161789595718159 4.9582724273212965e-05 0.001255275980043 +ER-Golgi transport 10 50 2.4969245379829466 0.012527561266806 13.189320388349516 50.09466019417476 1.0113245710455496 0.4417664900586612 5.844513029144237 4.526971021787617 1.2802141654412966 0.393016134031976 0.1354384523838074 0.0597604037758126 0.0439828576930944 0.0034841166529455 0.0005254830006891 +Lipid biosynthesis 13 49 2.20251223501711 0.0276291458404716 15.9126213592233 54.70145631067961 0.536392080403718 0.3712014565741516 7.84820404428356 6.53895703030749 1.480689631873909 0.3519149032884112 0.0164455262820106 0.0222515491745928 0.0315877089398048 0.0001971440903858 0.000308201649657 +Immunity 16 83 2.0289497341046125 0.0424634103727477 17.820388349514563 76.64077669902913 0.3712215805873788 0.6852303500560589 6.509274327939261 7.523560880911209 0.7685662507868273 0.3361567579513101 0.5583434366972468 0.6876756316847427 0.1925291945104754 0.1174896031262479 0.037752454879342 +Hydrogen ion transport 3 19 2.0046500139320047 0.0450004758323854 6.152912621359223 19.560679611650485 0.8019462838912398 0.3170771992837126 2.890966221074556 1.405159537040464 1.2709247974732976 0.29451915785821 0.2193453647012636 0.141543756104335 0.2613412907301976 0.0064140084647031 0.0623633603808868 +Translocation 5 46 1.9702520088600315 0.0488094956038955 12.434466019417476 47.86165048543689 1.1297087783550883 0.3515144245437065 6.687771513864753 3.601211391947168 1.550426642680832 0.3811939235350816 0.0027901475067936 0.0508992589190798 0.0057249284475035 0.0090935958038613 0.1522594518276387 diff --git a/protein_atlas_biological_process/metrics.json b/protein_atlas_biological_process/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..a09392aa4b8ade8be08ca9a8b7611429b4e08e06 --- /dev/null +++ b/protein_atlas_biological_process/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3329, + "annotations_size": 171, + "title": "Average number of proteins per term", + "value": 31.497076023391813 +} \ No newline at end of file diff --git a/protein_atlas_biological_process/paths.json b/protein_atlas_biological_process/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..077b1e10fe99f5c84d6a7674c8ae579726c9c4b6 --- /dev/null +++ b/protein_atlas_biological_process/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_biological_process/fragment/C342/C342_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_biological_process/result.tsv b/protein_atlas_biological_process/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..15c85d075522691dd7a736f568c5a5bd9f931cb3 --- /dev/null +++ b/protein_atlas_biological_process/result.tsv @@ -0,0 +1,57 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Steroid biosynthesis 0.7407833844770955 2.9184252761562157 0.0035180418236586 0.4526385130317865 0.0750150015800199 21 Q16850,Q15125,P37268,P48449,Q15392,Q15800,Q14739 7 +Sterol biosynthesis 0.7574908365276418 2.698762651199579 0.0069597793878004 0.6970789554111588 0.0750150015800199 16 Q16850,Q15125,P37268,Q15392,Q15800,Q14739 6 +Cholesterol biosynthesis 0.7574908365276418 2.698762651199579 0.0069597793878004 0.6970789554111588 0.0750150015800199 16 Q16850,Q15125,P37268,Q15392,Q15800,Q14739 6 +Cholesterol metabolism 0.6523604169004951 2.6381894550754117 0.0083350001755577 0.7609919675721222 0.0750150015800199 27 Q16850,Q15125,P37268,Q15392,Q15800,Q14739,P04062 7 +Sterol metabolism 0.6523604169004951 2.6381894550754117 0.0083350001755577 0.7609919675721222 0.0750150015800199 27 Q16850,Q15125,P37268,Q15392,Q15800,Q14739,P04062 7 +Transport 0.3671103574549841 2.5957336388407124 0.0094389205920413 0.80244162475045 0.076859781963765 510 Q9NS69,O43731,A6NIH7,P00846,Q70HW3,P24390,Q99595,Q9Y619,O43772,Q6NT16,Q8N4Q1,P41440,O43169,P21796,Q9BSK2,P45880,Q8IXU6,Q9H2D1,Q15629,P23786,Q8N4H5,O95563,Q9Y282,P46379,O75964,Q02978,Q03518,O00461,Q15363,O95197,Q99523,Q9HD20,Q96CU9,Q9Y487,Q9UMY4,O14949,O95373,O43676,Q93050,Q9UDW1,Q6DKK2,O43752,Q99720,P22626,P31749,P49257,Q9P260,Q9P2W9,Q7KZ85,O75306,O14925,Q9BTX1,Q96JB2,P12235,Q9NQ11,Q9P253,Q96S66,Q92973,O43823,Q96L92,P18085,Q8IUR0,O95721,Q9HAV4,Q9H1E5,Q9BVK6,P84085,O15027,Q96QD8,Q5T8D3,P20645,Q6P4A7,Q8N5M9,Q86Y39,Q01469,Q9Y6C9,Q9UBX3,Q92945,O15118,O15397,O75438,O95168,Q16134,Q06787,P53985,Q92783,Q9H4L5,Q9Y5X3 88 +Sphingolipid metabolism 0.8438842978063936 2.557532316482299 0.0105417762451462 0.8367075606446334 0.0819383517236371 10 Q16739,P17900,P07602,Q06136,Q9NZ01,O95470,O15270,P04062 8 +Steroid metabolism 0.631498892650803 2.5282092797575006 0.0114645990516935 0.8607898951152774 0.0845568797933558 28 Q16850,Q15125,P37268,Q15392,Q15800,Q14739,P04062 7 +ER-Golgi transport 0.5422417289497455 2.4969245379829466 0.012527561266806 0.8841830623964468 0.0856885190649537 50 Q9Y282,Q9P2W9,P18085,O95197,O43731,Q15363,Q8IUR0,P84085,P24390,P49257 10 +Lipid biosynthesis 0.5083736969703817 2.20251223501711 0.0276291458404716 0.9916965129419814 0.1592212297476403 49 Q16739,Q16850,Q15125,Q96G23,P37268,P48449,Q9UBM7,Q15392,Q15800,Q9NZ01,Q14739,P35790,O95674 13 +Immunity 0.4490777431920494 2.0289497341046125 0.0424634103727477 0.9994008029122652 0.2173971872614284 83 P14174,O43823,Q9UQ84,Q9NRW3,P46379,P25786,P10321,Q96FW1,P17812,Q8IV08,Q03518,Q9NUD5,P04083,Q9NZ08,Q96PK6,Q9Y5A9 16 +Hydrogen ion transport 0.5958292199000926 2.0046500139320047 0.0450004758323854 0.999619337988381 0.2198594676382259 19 P00846,O75964,Q9Y487 3 +Translocation 0.4840008555412562 1.9702520088600313 0.0488094956038955 0.9998078043525253 0.2255790202234093 46 Q99595,Q15629,Q9NS69,O14925,Q8N4Q1 5 +Glyoxylate bypass 0.9771565975353153 1.8587146864789037 0.0630675906225466 0.9999854751124396 0.2838041578014598 2 P48735 1 +Nucleotide metabolism 0.6730815151300426 1.80133739626032 0.0716497169744632 0.999996988863246 0.3141564513495695 11 Q969T7 1 +ATP synthesis 0.6937588466293751 1.73440489045387 0.08284626796873 0.999999621900998 0.3308181999954301 8 P00846 1 +Phospholipid metabolism 0.6378470282910311 1.7205512153705738 0.0853322924708024 0.9999997622983172 0.3316323184660731 12 Q9NPH0,P35790 2 +Adaptive immunity 0.5924683694912741 1.690200385060334 0.0909896247482051 0.9999999177242834 0.3382440398248496 14 Q96FW1,Q9NZ08,Q03518,P10321 4 +One-carbon metabolism 0.6414136510192664 1.6153303252803224 0.1062391798680992 0.999999995441264 0.3784770782801037 10 P00374,P34896 2 +Antiport 0.7408486445713682 1.5832313434695722 0.1133687449360434 0.9999999988410644 0.3877211076812685 6 P12235,P51790,O95202,P41440 4 +Vision 0.7223114480433033 1.5059360742463646 0.1320835848194967 0.9999999999698198 0.4124838951004781 6 P50897,O60313,Q9H6K4 3 +Sensory transduction 0.7223114480433033 1.5059360742463646 0.1320835848194967 0.9999999999698198 0.4124838951004781 6 P50897,O60313,Q9H6K4 3 +Ion transport 0.4274132001587284 1.4943565753162356 0.1350824451791039 0.9999999999833016 0.4124838951004781 50 P21796,P45880,Q93050,Q96QD8,O75964,Q9H813,Q9Y487,P00846,P16615,Q96S66 10 +Apoptosis 0.4104843077999994 1.287573982092762 0.1978943010208951 1.0 0.5287488355402041 124 O95197,O75832,Q13043,Q96F07,Q9Y3D6,P42574,O00571,P42858,Q9UBK9,Q03164,O43683,P09601,Q9UHX1,Q01085,P21796,Q9BXK5,Q15041,Q13546,Q13177,P31749,Q9Y2I1,O60566,Q16539,Q9H2J4,Q9UDX5,O95470,O75340,O60313,O95817,P46379,Q9NR28,O95831,P28482,Q9H8M7,Q86W42,O14737,Q9H3K2,Q00535,P10909,O95140,Q96A26,Q96KA5 42 +Amino-acid transport 0.6169140660683418 1.209221101302594 0.2265779129931282 1.0 0.5570905114757138 7 Q96QD8,Q6P4A7 2 +Symport 0.590876794405441 1.0919937413145562 0.2748358521404301 1.0 0.6027832460895945 7 Q96QD8,P53985,Q9H2J7,P55011 4 +Complement pathway 0.778178539224526 1.0465285657522352 0.2953170633374005 1.0 0.6312402228836935 2 P10909 1 +Inflammatory response 0.5167303343487802 1.0111719217185529 0.3119341520611862 1.0 0.6504968292983274 11 P14174,P04083,Q8IV08 3 +Prostaglandin biosynthesis 0.7556357078449072 0.9570969256336296 0.3385183352276719 1.0 0.6810192391050812 2 Q9H7Z7 1 +Hypusine biosynthesis 0.7484220018034101 0.9287859006326732 0.3530000527731629 1.0 0.6833277594018908 2 Q9BU89 1 +Unfolded protein response 0.5053327701430714 0.9127690938095606 0.3613639962065611 1.0 0.6843458838438664 9 Q15629,O95140 2 +Electron transport 0.3630226845224454 0.8848008717394998 0.3762640392250618 1.0 0.6843458838438664 49 O43676,Q9H1E5,Q96CU9,Q9UDW1,O75306,O75438,O95168,Q16134,Q86Y39,Q6DKK2,O43169,O14949 12 +Tricarboxylic acid cycle 0.4176447638745828 0.8786797312829691 0.3795749514515769 1.0 0.6843458838438664 20 P48735 1 +Oogenesis 0.6754978215618693 0.8694862810223493 0.3845812086404576 1.0 0.6843458838438664 4 Q9Y5A9,Q15645 2 +Prostaglandin metabolism 0.75586289837642 0.8594233750216885 0.3901069780427755 1.0 0.6843458838438664 3 Q9H7Z7,Q14914 2 +Angiogenesis 0.4991162108185383 0.8111144974587049 0.4172999211011161 1.0 0.6843458838438664 8 Q9H2J4,P35613 2 +Glycogen biosynthesis 0.5793015591600696 0.8055265842063246 0.4205158719419524 1.0 0.6843458838438664 5 P31749,Q04446,P46976 3 +Neurotransmitter transport 0.713856327021338 0.7957544426076921 0.4261747760143786 1.0 0.6843458838438664 2 Q9H2J7 1 +Phospholipid biosynthesis 0.4741452574381246 0.792247408657219 0.4282164302414837 1.0 0.6843458838438664 11 P48651,Q96N66,Q92604,Q9HCL2,P35790,O95674 6 +Respiratory chain 0.3707859982171841 0.7447287994769102 0.4564356853190512 1.0 0.7055356383456324 35 O43676,Q96CU9,Q9UDW1,O75306,O75438,O95168,Q86Y39,Q6DKK2,O14949 9 +Lipid metabolism 0.3605348589622626 0.7280178858867665 0.4666026375776158 1.0 0.7109422609198003 121 Q16739,P37268,Q16836,Q9NPH0,Q9P035,Q15392,Q8NHP8,P51648,Q15067,O15118,P07602,Q06136,Q14739,Q9BY49,P35790,A1L0T0,P17900,Q96G23,Q15800,Q14914,Q13510,P04062,Q16850,P48449,P23786,Q8NCC3,Q9NZ01,P49327,O95470,O15270,Q8N2K0,Q15125,Q9UBM7,O95674 34 +Peroxisome biogenesis 0.6825969341749328 0.6802260946117739 0.4963613120116901 1.0 0.7193032572372797 2 P40855 1 +Glucose metabolism 0.4512468392650096 0.6460722174858212 0.5182325869286664 1.0 0.7263751833180488 9 P31749 1 +Phagocytosis 0.6495341148181573 0.5646205423371891 0.5723318897964929 1.0 0.75919758638126 2 P50570 1 +Sodium transport 0.4692822122358626 0.4618106447352638 0.6442171166633579 1.0 0.7982690358654653 6 Q96QD8,P55011,P05023 3 +Innate immunity 0.3086033814737914 0.4017566267349308 0.6878631455436803 1.0 0.8283422386476714 62 P14174,O43823,O00571,Q9NRW3,P10321,O94992,Q9Y5A9,Q9NUD5,P04083,P04439,P01889,P10909,Q96PK6,O60828 14 +Chemotaxis 0.4824060150375975 0.2484158422955525 0.8038126772975076 1.0 0.9271334613216732 4 P26583,P09429,O94813 3 +Potassium transport 0.4179845973535058 0.2384023050705277 0.8115690797747459 1.0 0.9271334613216732 5 P55011,Q96ER9 2 +Meiosis 0.3353456176008594 0.2362032392491626 0.8132749660716432 1.0 0.9271334613216732 14 Q9H6S0,O94901,Q15645,Q9UQ84 4 +Pyrimidine biosynthesis 0.3923919429306008 0.2057986792075897 0.8369481729577308 1.0 0.9478022356011389 6 P17812 1 +Cilium biogenesis/degradation 0.3056738080521781 0.1882838917293029 0.8506541120664113 1.0 0.9569858760747127 24 O95684,A6NIH7 2 +Autophagy 0.2933492590237221 0.1523068216600535 0.8789449447858657 1.0 0.9823502324077322 38 Q9BXS4,Q5T8D3,P53365,Q9HA65,Q969Q5,Q9P253,O95721,O95140 8 +tRNA processing 0.2960626022111596 0.1427721370375766 0.8864701430346154 1.0 0.9843272367462288 31 O75648,Q08J23,Q96PZ0,Q5VV42,P62312 5 +DNA synthesis 0.4544634806131601 0.1145631742619546 0.908791370147775 1.0 1.0 2 P35232 1 +GPI-anchor biosynthesis 0.3302790384737875 0.053590249418801 0.957261625186358 1.0 1.0 5 Q9Y2B2 1 +Sodium/potassium transport 0.3162958508719237 0.0261043846911791 0.9791740797778694 1.0 1.0 3 P05026,P05023 2 diff --git a/protein_atlas_biological_process/selections.json b/protein_atlas_biological_process/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..d57419ae3b5c8df57d7b2b83f65285c747cdf223 --- /dev/null +++ b/protein_atlas_biological_process/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthesis", "Activation of host autophagy by virus", "Adaptive immunity", "Amino-acid biosynthesis", "Amino-acid transport", "Angiogenesis", "Antiport", "Antiviral defense", "Apoptosis", "Aromatic hydrocarbons catabolism", "Asparagine biosynthesis", "Autophagy", "B-cell activation", "Behavior", "Biological rhythms", "Biomineralization", "Branched-chain amino acid biosynthesis", "Branched-chain amino acid catabolism", "Calcium transport", "Carbohydrate metabolism", "Carnitine biosynthesis", "Catecholamine metabolism", "Cell adhesion", "Cell cycle", "Cell division", "Cell shape", "Chemotaxis", "Cholesterol biosynthesis", "Cholesterol metabolism", "Chromosome partition", "Cilium biogenesis/degradation", "Coenzyme A biosynthesis", "Collagen degradation", "Complement pathway", "Cysteine biosynthesis", "DNA condensation", "DNA damage", "DNA excision", "DNA recombination", "DNA repair", "DNA replication", "DNA synthesis", "Detoxification", "Differentiation", "ER-Golgi transport", "Electron transport", "Endocytosis", "Exocytosis", "Fatty acid biosynthesis", "Fatty acid metabolism", "Fertilization", "Fucose metabolism", "GMP biosynthesis", "GPI-anchor biosynthesis", "Galactose metabolism", "Gastrulation", "Gluconate utilization", "Gluconeogenesis", "Glucose metabolism", "Glutathione biosynthesis", "Glycogen biosynthesis", "Glycogen metabolism", "Glycolysis", "Glyoxylate bypass", "Growth arrest", "Growth regulation", "Hearing", "Heme biosynthesis", "Host-virus interaction", "Hydrogen ion transport", "Hypusine biosynthesis", "Immunity", "Inflammatory response", "Inhibition of host STAT1 by virus", "Inhibition of host STAT2 by virus", "Inhibition of host innate immune response by virus", "Inhibition of host interferon signaling pathway by virus", "Innate immunity", "Inositol biosynthesis", "Ion transport", "Isoprene biosynthesis", "Keratinization", "Leukotriene biosynthesis", "Lipid biosynthesis", "Lipid degradation", "Lipid metabolism", "Lipid transport", "Meiosis", "Melanin biosynthesis", "Methionine biosynthesis", "Methotrexate resistance", "Mitosis", "Molybdenum cofactor biosynthesis", "Myogenesis", "Necrosis", "Neurogenesis", "Neurotransmitter degradation", "Neurotransmitter transport", "Nonsense-mediated mRNA decay", "Notch signaling pathway", "Nucleotide biosynthesis", "Nucleotide metabolism", "One-carbon metabolism", "Oogenesis", "Osteogenesis", "Pentose shunt", "Peptide transport", "Peroxisome biogenesis", "Phagocytosis", "Phenylalanine catabolism", "Phospholipid biosynthesis", "Phospholipid metabolism", "Plasminogen activation", "Polyamine biosynthesis", "Porphyrin biosynthesis", "Potassium transport", "Proline biosynthesis", "Proline metabolism", "Prostaglandin biosynthesis", "Prostaglandin metabolism", "Protein biosynthesis", "Protein transport", "Purine biosynthesis", "Purine salvage", "Pyridine nucleotide biosynthesis", "Pyridoxine biosynthesis", "Pyrimidine biosynthesis", "RNA repair", "RNA-mediated gene silencing", "Respiratory chain", "Ribosome biogenesis", "Sensory transduction", "Serine biosynthesis", "Sodium transport", "Sodium/potassium transport", "Spermatogenesis", "Spermidine biosynthesis", "Sphingolipid metabolism", "Steroid biosynthesis", "Steroid metabolism", "Sterol biosynthesis", "Sterol metabolism", "Stress response", "Sugar transport", "Symport", "Tetrahydrobiopterin biosynthesis", "Transcription", "Transcription regulation", "Transcription termination", "Translation regulation", "Translocation", "Transport", "Tricarboxylic acid cycle", "Tyrosine catabolism", "Ubiquinone biosynthesis", "Ubl conjugation pathway", "Unfolded protein response", "Viral RNA replication", "Viral immunoevasion", "Viral penetration into host nucleus", "Virus entry into host cell", "Vision", "Wnt signaling pathway", "Xylose metabolism", "Zinc transport", "mRNA capping", "mRNA processing", "mRNA splicing", "mRNA transport", "rRNA processing", "tRNA processing"], "available_proteins": ["AAAS", "AACS", "AAGAB", "AAK1", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "ABCB1", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF3", "ABHD12", "ABHD6", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACADM", "ACADVL", "ACAT1", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOX1", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN4", "ACTR3", "ADA", "ADAM17", "ADAR", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFDN", "AGL", "AGPS", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AKAP8", "AKAP8L", "AKT1", "ALCAM", "ALDH18A1", "ALDH3A2", "ALDH4A1", "ALDOA", "ALDOC", "ALG13", "ALKBH1", "ALKBH5", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APC", "APEX1", "API5", "APOBEC3C", "APOO", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP3", "ARFIP2", "ARHGAP35", "ARHGEF2", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL8B", "ARMC10", "ARMC9", "ARMT1", "ARVCF", "ASAH1", "ASB6", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ATAD2", "ATAD5", "ATE1", "ATF7IP", "ATG3", "ATG4B", "ATG9A", "ATIC", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATRX", "AUP1", "BABAM1", "BABAM2", "BAG3", "BAG6", "BANF1", "BAX", "BAZ1A", "BAZ1B", "BCAP31", "BCAS2", "BCAT2", "BCCIP", "BCL2L12", "BCL2L13", "BCLAF1", "BCOR", "BICD2", "BIRC6", "BLM", "BMS1", "BNIP1", "BOD1L1", "BOP1", "BPTF", "BRAP", "BRAT1", "BRCA1", "BRD2", "BRD4", "BRIX1", "BSG", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C1QBP", "C2CD5", "CACTIN", "CACUL1", "CACYBP", "CAD", "CADM1", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CANX", "CAPRIN1", "CARM1", "CARS", "CASP2", "CASP3", "CBL", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC124", "CCDC22", "CCDC51", "CCDC86", "CCDC88A", "CCDC93", "CCDC94", "CCNA2", "CCNB1", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC23", "CDC25C", "CDC27", "CDC42", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP3", "CDK6", "CDKAL1", "CDS2", "CDX2", "CEBPZ", "CELF1", "CENPE", "CENPU", "CENPV", "CEP250", "CEP55", "CERS2", "CETN2", "CFL1", "CHAF1A", "CHAF1B", "CHCHD3", "CHCHD4", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK1", "CHEK2", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP4A", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHP1", "CHST14", "CHTF18", "CHTF8", "CHTOP", "CIAPIN1", "CIRBP", "CISD2", "CKAP2", "CKAP5", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLIC1", "CLIC4", "CLINT1", "CLPTM1", "CLPTM1L", "CLSPN", "CLTA", "CLTC", "CLU", "CMPK1", "CNNM3", "CNOT1", "CNOT11", "CNOT3", "CNOT7", "CNOT9", "COASY", "COG2", "COG3", "COG7", "COMMD1", "COMMD10", "COMMD2", "COMMD7", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS6", "COPS7A", "COPZ1", "COQ8A", "COX2", "CPNE1", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRNKL1", "CS", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC15", "CWC22", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DCAF1", "DCAF7", "DCAF8", "DCP1A", "DCP1B", "DCP2", "DCPS", "DCTD", "DCTN1", "DCTN3", "DCXR", "DDA1", "DDB1", "DDRGK1", "DDT", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX46", "DDX47", "DDX5", "DDX51", "DDX54", "DDX56", "DENND4C", "DENR", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHODH", "DHPS", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DICER1", "DIDO1", "DIMT1", "DIP2B", "DIS3", "DIS3L2", "DKC1", "DLAT", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA3", "DNAJB1", "DNAJC2", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DPF2", "DPY30", "DPYSL2", "DSC3", "DSG2", "DST", "DTL", "DTYMK", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECH1", "ECHS1", "ECI1", "ECSIT", "ECT2", "EDF1", "EDRF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EGFR", "EHBP1", "EHD1", "EIF2A", "EIF2AK2", "EIF2AK4", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELL", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP4", "EMG1", "EML4", "ENO1", "ENO2", "ENSA", "EPB41", "EPB41L2", "EPHX1", "EPHX2", "EPN1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERO1A", "ERP44", "ESF1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6B", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FABP5", "FAF1", "FAF2", "FAH", "FAM160A2", "FAM162A", "FAM208A", "FAM50A", "FAM83D", "FANCA", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FBL", "FBXO22", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FIP1L1", "FIS1", "FKBP8", "FLII", "FLNA", "FLNB", "FLOT2", "FMR1", "FOXRED1", "FRYL", "FTSJ3", "FUBP1", "FUBP3", "FXR1", "G3BP1", "G3BP2", "G6PD", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCC2", "GCFC2", "GCLM", "GCN1", "GEMIN4", "GEMIN5", "GEMIN8", "GET4", "GFM1", "GFPT1", "GGA1", "GGT7", "GHITM", "GID8", "GINS3", "GINS4", "GLRX", "GM2A", "GMPS", "GNAI1", "GNAI2", "GNAI3", "GNL2", "GNL3L", "GNPDA1", "GOLGA2", "GOLIM4", "GOLPH3", "GOLT1B", "GOPC", "GORASP2", "GOT1", "GOT2", "GPAM", "GPHN", "GPI", "GPKOW", "GPR89B", "GPSM1", "GRB2", "GRSF1", "GRWD1", "GSDME", "GSK3A", "GSK3B", "GSPT1", "GSS", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP10", "GTPBP3", "GTPBP4", "GYG1", "GYS1", "H2AFX", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAUS1", "HAUS2", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HECTD1", "HELLS", "HERC4", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HINT2", "HIP1", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCS1", "HMGXB4", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOXD13", "HPRT1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA6", "HSPA8", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HUS1", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IER3IP1", "IFIT5", "IFT27", "IFT88", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBKB", "IKBKG", "ILF2", "ILF3", "ILVBL", "IMP3", "IMPDH1", "IMPDH2", "INA", "INCENP", "INTS13", "INTS3", "INTS7", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IRF2BP1", "ISG20L2", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITSN2", "IVD", "IWS1", "JAGN1", "JMJD6", "JUP", "KARS", "KAT7", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0391", "KIAA1468", "KIF11", "KIF1B", "KIF20A", "KIF20B", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF5C", "KIFBP", "KIFC1", "KIN", "KLC1", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRR1", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDLR", "LDLRAP1", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LPCAT1", "LPGAT1", "LRP1", "LRPPRC", "LRRC41", "LRWD1", "LSM14A", "LSM14B", "LSM2", "LSM6", "LSS", "LTA4H", "LTN1", "LUC7L3", "LYAR", "LYPLA1", "LZTS2", "M6PR", "MACF1", "MAD1L1", "MAGED1", "MAGT1", "MANF", "MAP1S", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCH5", "MARK1", "MARK2", "MARS", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBOAT7", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MEAF6", "MECP2", "MED1", "MED14", "MED16", "MED21", "MED23", "MED24", "MED4", "METTL1", "METTL3", "MFAP1", "MFN2", "MFSD10", "MFSD5", "MGEA5", "MGME1", "MGST2", "MIA3", "MICALL1", "MICU1", "MID1", "MIF", "MINDY3", "MKI67", "MKRN2", "MLEC", "MMGT1", "MMS19", "MOB4", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MRC2", "MRE11", "MRPL58", "MRPS27", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTERF3", "MTFP1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR2", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MTX3", "MVK", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYH10", "MYH14", "MYH9", "MYO1C", "MYO1D", "MYO6", "NAA15", "NACC1", "NAE1", "NAMPT", "NAP1L1", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCKAP1", "NCOA5", "NCOR1", "NCSTN", "ND5", "NDC1", "NDC80", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF4", "NDUFB1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEK9", "NELFA", "NELFCD", "NELFE", "NES", "NFKB1", "NFS1", "NHP2", "NIP7", "NIPBL", "NISCH", "NKRF", "NLE1", "NMD3", "NME1", "NME2", "NME3", "NOC2L", "NOL11", "NOL8", "NOL9", "NONO", "NOP14", "NOP2", "NOP53", "NOP56", "NOP58", "NOSIP", "NPC1", "NPC2", "NPLOC4", "NPM1", "NPTN", "NRDE2", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NUCKS1", "NUDC", "NUDCD1", "NUDT16", "NUDT21", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NVL", "NXF1", "NXN", "OCRL", "OGDH", "OGT", "OPA1", "OPA3", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "PA2G4", "PABPC1", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1", "PAK1IP1", "PAK2", "PAK4", "PANK4", "PAPOLA", "PARG", "PARK7", "PARN", "PARP1", "PAXIP1", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCK2", "PCM1", "PCNA", "PCNP", "PDCD11", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDK3", "PDLIM7", "PDS5A", "PDS5B", "PDZD8", "PECR", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", 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0000000000000000000000000000000000000000..2af0d730a7b43f32bc747b726f98af5b1ec55a1a --- /dev/null +++ b/protein_atlas_disease_involvement/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Dwarfism 7 53 2.169107712992912 0.0300745072652579 10.859223300970871 47.58009708737864 0.0720913494292303 0.7126823901634942 4.96488517829283 6.846861090068248 0.6438504877340618 0.2938209241572714 0.0217958429457797 0.0041154920344419 0.0412611149036703 0.016492219367271 0.0307307574131444 +Neuronal ceroid lipofuscinosis 2 5 2.010030217633415 0.0444279907683387 2.1941747572815533 3.616504854368932 0.8145003765175237 0.1716854616439567 0.950812145720796 0.8293870806734848 1.6764073513361384 0.2241811956153294 0.091321621191287 1.0 0.1105474823156849 0.0331187861076589 0.0183139901045195 diff --git a/protein_atlas_disease_involvement/metrics.json 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index 0000000000000000000000000000000000000000..57eb9692726697c1bffc9bca2e05c410d4a04b12 --- /dev/null +++ b/protein_atlas_disease_involvement/result.tsv @@ -0,0 +1,37 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Dwarfism 0.4993859395441534 2.169107712992912 0.0300745072652579 0.971049811322608 0.3825867122018396 53 Q15125,Q32P28,O95831,Q96PZ0,O43909,Q14739,Q7RTS9 7 +Neuronal ceroid lipofuscinosis 0.8755150236923995 2.010030217633415 0.0444279907683387 0.9948648078177352 0.3825867122018396 5 P50897,O75503 2 +Osteogenesis imperfecta 0.7424808561121677 1.765311192833975 0.077511479418624 0.9999138068842572 0.4732279796084414 7 Q96AY3 1 +Gaucher disease 0.9428914938382926 1.7188936935241153 0.0856337306990093 0.9999691011144378 0.4966756380542543 2 P07602 1 +Ichthyosis 0.6393246303565054 1.6050718196875031 0.1084780001332605 0.9999983582028557 0.5062199486393415 10 O95721,Q15125,P51648,P04062 4 +Deafness 0.4360432429086516 1.588861438171529 0.1120916788393726 0.999998975050134 0.5062199486393415 52 Q16740,Q9NR28,O95831,Q969T9,Q15067,Q9NWM8,O60313,Q8N2K0 8 +Neuropathy 0.432401028350016 1.5828173898683275 0.1134630919364041 0.999999143295188 0.5062199486393415 55 Q5TAQ9,Q9NSE4,O95831,Q15067,P07196,P00846,O15270,Q15120,O95140,Q7LG56,Q8N2K0 11 +Cataract 0.4818925819142499 1.55109219730682 0.1208795908114013 0.9999996766967636 0.5193345383008353 31 Q15125,Q9NSE4,P48449,Q15800,Q9H6K4,Q8N2K0 6 +Ehlers-Danlos syndrome 0.8128986235128999 1.3960870486064394 0.1626882834320999 0.9999999988652204 0.6329370009527588 4 Q8NCH0 1 +Progressive external ophthalmoplegia 0.7225398400201397 1.3927658655371944 0.163690603694679 0.9999999990124268 0.6329370009527588 5 P51530,Q7LG56 2 +Autism 0.6525330048846391 1.211955965927867 0.2255292369774555 0.9999999999998668 0.674069565235386 6 P06730 1 +Primary mitochondrial disease 0.3844063193666319 1.189109415834491 0.2343966136376964 0.9999999999999648 0.6797501795493197 98 Q9Y2R0,Q9UBX3,P12235,Q96CU9,Q9NPL8,P00846,Q70HW3,Q8NFF5,O14949,O43676,Q6DKK2,P51530,O75880,Q7LG56,Q8NI60,Q9Y6M9,Q9NYY8,Q9BW92,O60313,Q5XKP0,P20674,O95831,O75306,Q6P4A7,Q86Y39 25 +Long QT syndrome 0.8016230838593321 1.1407791371563687 0.2539618445951874 0.9999999999999982 0.7014184279295653 2 P0DP25 1 +Congenital myasthenic syndrome 0.8257936229195507 1.112485467778513 0.2659294750047922 0.9999999999999998 0.717391141873393 3 Q4J6C6 1 +Parkinsonism 0.5236977049318561 1.0250989942925888 0.3053164800327268 1.0 0.7811802911716722 10 Q9NQ11,P04062 2 +Niemann-Pick disease 0.7571385632702015 0.9630153488872027 0.335539820654509 1.0 0.8281408339558096 2 O15118 1 +Retinitis pigmentosa 0.425419674396481 0.8694414830890658 0.3846057016299278 1.0 0.8522146061611896 18 P00846,Q8N2K0 2 +Rhizomelic chondrodysplasia punctata 0.7483463619963855 0.8329025241585336 0.4048997059713706 1.0 0.8522146061611896 3 O15228,O00116 2 +Palmoplantar keratoderma 0.4947127483940206 0.7902431567926421 0.4293857765620443 1.0 0.8522146061611896 8 Q06136 1 +Autism spectrum disorder 0.4487930695049894 0.7861154498254685 0.4317998537816494 1.0 0.8522146061611896 13 P06730 1 +Schizophrenia 0.7105500450856429 0.7832948603129395 0.4334539807199153 1.0 0.8522146061611896 2 P21964 1 +Cardiomyopathy 0.3809626565734432 0.7365919578649647 0.4613705270424932 1.0 0.8917505516411746 26 P00846,P09493,O60313 3 +FDA approved drug targets 0.3619732526772211 0.708060977309378 0.4789073913560673 1.0 0.8917505516411746 126 P62942,Q16739,P15260,Q16836,P12235,Q96ER9,P28074,P48735,Q16134,P42574,P00374,P20618,Q9NR33,P21964,P49721,Q7LG56,Q16850,Q99720,P23786,O75874,Q9Y2I1,P49327,P02786,P38435,Q96QD8,P49356,P20645,P16615,P04083,Q8N0U8,P28482 31 +Gangliosidosis 0.5488945678510702 0.6855442464424275 0.4930005498464802 1.0 0.8923561130732839 5 P07602 1 +Dystroglycanopathy 0.6115090533532447 0.6374487202982877 0.5238326019710025 1.0 0.8923561130732839 4 O43505 1 +Congenital muscular dystrophy 0.5158781991868719 0.5600055262604167 0.5754756682882027 1.0 0.8923561130732839 5 O43505 1 +Proto-oncogene 0.3257993874153531 0.5123725614752377 0.6083902905380834 1.0 0.8923561130732839 45 Q92804,P46108,Q01844,Q01105,Q92733,Q06136,P31749,Q92734,P35637 9 +Parkinson disease 0.4743197515896511 0.4805962808647226 0.6308034592414593 1.0 0.8923561130732839 6 Q6Y7W6,P04062 2 +Mucopolysaccharidosis 0.4803870431424911 0.4329147481011797 0.6650767052927811 1.0 0.9008511894146076 5 Q96AX1,P54802,P08236 3 +Amyotrophic lateral sclerosis 0.3520743731095903 0.3585659946806448 0.7199197896417633 1.0 0.9466053240397174 16 P35637 1 +Diabetes mellitus 0.3838216621506363 0.3500851775714737 0.7262747744787488 1.0 0.9466053240397174 11 O60343 1 +Lissencephaly 0.3692785340885054 0.2788354350997431 0.7803711192192988 1.0 1.0 10 O43505,Q00535 2 +Charcot-Marie-Tooth disease 0.3061628069158718 0.199702363541446 0.8417133651719468 1.0 1.0 25 O95831,Q15120,O95140 3 +Primary microcephaly 0.3285490827178358 0.1209324744387949 0.9037445200453254 1.0 1.0 11 Q86XL3 1 +Peroxisome biogenesis disorder 0.283523752254965 0.0233930650202007 0.9813367368060468 1.0 1.0 3 P40855,P50542 2 +Zellweger syndrome 0.283523752254965 0.0233930650202007 0.9813367368060468 1.0 1.0 3 P40855,P50542 2 diff --git a/protein_atlas_disease_involvement/selections.json b/protein_atlas_disease_involvement/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..0c95a650019544f49dfbecc0650ece8cae906d34 --- /dev/null +++ b/protein_atlas_disease_involvement/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Aicardi-Goutieres syndrome", "Albinism", "Allergen", "Alport syndrome", "Alzheimer disease", "Amyloidosis", "Amyotrophic lateral sclerosis", "Atherosclerosis", "Atrial fibrillation", "Autism", "Autism spectrum disorder", "Bardet-Biedl syndrome", "Bartter syndrome", "Cancer-related genes", "Cardiomyopathy", "Cataract", "Charcot-Marie-Tooth disease", "Ciliopathy", "Cockayne syndrome", "Cone-rod dystrophy", "Congenital adrenal hyperplasia", "Congenital disorder of glycosylation", "Congenital erythrocytosis", "Congenital hypothyroidism", "Congenital muscular dystrophy", "Congenital myasthenic syndrome", "Craniosynostosis", "Cushing syndrome", "Deafness", "Diabetes insipidus", "Diabetes mellitus", "Diamond-Blackfan anemia", "Disease variant", "Dwarfism", "Dyskeratosis congenita", "Dystonia", "Dystroglycanopathy", "Ectodermal dysplasia", "Ehlers-Danlos syndrome", "Elliptocytosis", "Emery-Dreifuss muscular dystrophy", "Epidermolysis bullosa", "Epilepsy", "FDA approved drug targets", "Fanconi anemia", "Gangliosidosis", "Gaucher disease", "Glaucoma", "Glutaricaciduria", "Glycogen storage disease", "Gout", "Hereditary hemolytic anemia", "Hereditary nonpolyposis colorectal cancer", "Hereditary spastic paraplegia", "Hermansky-Pudlak syndrome", "Hirschsprung disease", "Holoprosencephaly", "Hyperlipidemia", "Hypogonadotropic hypogonadism", "Hypotrichosis", "Ichthyosis", "Intrahepatic cholestasis", "Joubert syndrome", "Kallmann syndrome", "Kartagener syndrome", "Leber congenital amaurosis", "Leber hereditary optic neuropathy", "Leigh syndrome", "Leukodystrophy", "Li-Fraumeni syndrome", "Limb-girdle muscular dystrophy", "Lissencephaly", "Long QT syndrome", "MELAS syndrome", "Maple syrup urine disease", "Meckel syndrome", "Mental retardation", "Metachromatic leukodystrophy", "Microphthalmia", "Mucopolysaccharidosis", "Myofibrillar myopathy", "Nemaline myopathy", "Nephronophthisis", "Neurodegeneration", "Neuronal ceroid lipofuscinosis", "Neuropathy", "Niemann-Pick disease", "Non-syndromic deafness", "Obesity", "Oncogene", "Osteogenesis imperfecta", "Osteopetrosis", "Palmoplantar keratoderma", "Parkinson disease", "Parkinsonism", "Peroxisome biogenesis disorder", "Phenylketonuria", "Pontocerebellar hypoplasia", "Premature ovarian failure", "Primary ciliary dyskinesia", "Primary hypomagnesemia", "Primary microcephaly", "Primary mitochondrial disease", "Progressive external ophthalmoplegia", "Proto-oncogene", "Pyropoikilocytosis", "Retinitis pigmentosa", "Rhizomelic chondrodysplasia punctata", "SCID", "Schizophrenia", "Spinocerebellar ataxia", "Systemic lupus erythematosus", "Tumor suppressor", "Williams-Beuren syndrome", "Xeroderma pigmentosum", "Zellweger syndrome"], "available_proteins": ["AAAS", "AAGAB", "AARS", "AARS2", "ABCB1", "ABCB7", "ABHD11", "ABHD12", "ACAA1", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOX1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ADA", "ADAR", "ADD3", "ADK", "ADNP", "ADPRHL2", "ADSL", "AFDN", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AKAP12", "AKAP13", "AKAP9", "AKR1B1", "AKT1", "ALCAM", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG13", "ANAPC1", "ANK3", "ANKLE2", "ANLN", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA7", "AP1B1", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "APC", "APEX1", "APPL1", "APRT", "ARCN1", "ARHGAP35", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID3B", "ARIH1", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARMC9", "ARPC1B", "ASAH1", "ASCC1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD3A", "ATIC", "ATL3", "ATP13A2", "ATP1A1", "ATP2A2", "ATP2B1", "ATP5A1", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATRX", "ATXN10", "ATXN2", "B3GALT6", "B4GALT1", "B4GAT1", "BAG3", "BANF1", "BAX", "BAZ1B", "BCAP31", "BCAT2", "BCLAF1", "BCOR", "BCS1L", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRB", "BMS1", "BPTF", "BRAT1", "BRCA1", "BRD4", "BRI3BP", "BUB1B", "BUD23", "C19orf70", "C1QBP", "C21orf59", "CAD", "CADM1", "CALM3", "CALR", "CAMK2G", "CANX", "CAP2", "CAPN1", "CARM1", "CARS", "CASK", "CASP2", "CASP3", "CAST", "CBL", "CCAR1", "CCAR2", "CCDC22", "CCDC47", "CCDC51", "CCDC6", "CCDC88A", "CCNA2", "CCNB1", "CCT5", "CDC25C", "CDC27", "CDC37", "CDC42", "CDC45", "CDC73", "CDH2", "CDK1", "CDK4", "CDK5", "CDK6", "CDKAL1", "CDX2", "CENPE", 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overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Protease 34 84 3.385823761145069 0.0007096494314526 20.788834951456312 82.44417475728156 1.1215350835872162 0.3507517256058336 6.07090559629836 8.079357013764625 1.4678877461728397 0.3691345771929886 0.0022884762496288 0.0258595758887776 1.333514718851362e-05 0.0001537167307229 2.0186099294413206e-05 +Receptor 19 39 3.217930264195678 0.0012911920640368 13.475728155339803 38.71116504854369 1.6655960679271569 0.1791616261110447 5.431559450288914 6.105192092581698 1.9169648296245776 0.2753083483896962 0.0484780309070854 0.0073420453854683 0.0958446637688343 0.0419027565404997 0.2409297676277974 +Rotamase 6 23 3.0655032035197545 0.0021730404961168 5.225728155339806 21.04368932038835 0.2903016415772153 0.5738010430803833 3.1033990453756255 2.0966996675039535 0.9519067598216118 0.3277712839255824 0.0015207949208565 0.0003706576678266 0.0001648499359412 4.571066233230639e-06 5.2876838988133375e-05 +Metalloprotease 15 27 2.751975830640879 0.0059236892641201 8.160194174757281 26.429611650485437 1.390302281711237 0.2661274848815638 3.192614043118206 1.543038499308978 1.1108461579919544 0.309446154241223 0.371181177773541 0.2486824788491954 0.0186371594327644 0.0027389701542927 1.840820968640247e-05 +Isomerase 9 59 2.536941158567968 0.0111825748002638 16.95631067961165 57.978155339805824 -0.7599054392440793 0.4672283813397911 7.568010985219974 5.062906078178033 0.8880781526733524 0.3235339671071414 0.0014505337934195 0.0016998925321585 0.0005336694844017 0.000229790615511 0.0017502036768962 +Carboxypeptidase 4 6 2.165367911045634 0.0303595214267731 3.1359223300970873 6.150485436893204 0.9957728306848488 0.1212034427500092 1.2071674596015187 0.4479454254223922 1.8250051834990677 0.2074401112551974 0.0061207505190791 0.0711332726649859 1.0516191954151127e-05 0.0003774704498572 0.000543833852376 +Dioxygenase 6 21 2.099869712711755 0.0357403037005235 4.485436893203883 16.929611650485437 0.3291673001296444 0.5856007381165738 2.3948329397108954 3.0857324105273336 0.8401407542250483 0.3144845391083291 0.086864214346425 0.0369748680428621 0.1215022402141297 0.0038382700604267 0.030712608331405 +Serine protease 2 8 1.995318526984359 0.0460081504983032 2.325242718446602 9.143203883495143 0.6368444182316527 0.3935197397745671 1.3833418412762697 1.1580773433535438 0.9813004733593778 0.2874962562446074 0.1743971944450219 0.1114073342812727 0.208984012191681 0.1147066696002357 0.1098061730973064 diff --git a/protein_atlas_molecular_function/metrics.json b/protein_atlas_molecular_function/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..dc7c1a8753097e1c483a12b83a650513b10563c1 --- /dev/null +++ b/protein_atlas_molecular_function/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3329, + "annotations_size": 96, + "title": "Average number of proteins per term", + "value": 40.6875 +} \ No newline at end of file diff --git a/protein_atlas_molecular_function/paths.json b/protein_atlas_molecular_function/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..d3c51203e9135a4bd626f3c361c07f47c70721f5 --- /dev/null +++ b/protein_atlas_molecular_function/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_molecular_function/fragment/C342/C342_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_molecular_function/result.tsv b/protein_atlas_molecular_function/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..e3d1b235da88cf0ea2d37fc3979a9bfa831fcd9e --- /dev/null +++ b/protein_atlas_molecular_function/result.tsv @@ -0,0 +1,32 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Protease 0.5881401543093064 3.385823761145069 0.0007096494314526 0.0658801498554221 0.0619772190737678 84 Q16740,O75844,Q9UIQ6,P42785,P28074,Q9Y4E8,Q96FZ2,P42574,Q96FW1,Q4J6C6,Q96K76,Q99797,P48147,P28072,P09960,Q7Z2K6,Q8TCT8,O95630,Q9HB40,P67812,Q99436,P42892,P07858,Q96TA2,Q9NZ08,Q9H3G5,P10619,Q9BYT8,P78536,Q9H8M7,P55786,Q86TI2,Q5JRX3,O75976 34 +Receptor 0.6829280699595299 3.217930264195678 0.0012911920640368 0.1166506631031629 0.0619772190737678 39 Q5KU26,P15260,Q99523,Q8WTV0,Q9NS69,O15118,O43731,Q9UBG0,Q14739,P24390,Q14108,O00264,Q99720,Q9Y2I1,P35613,P02786,P20645,O15173,Q9Y5M8 19 +Rotamase 0.7515430944089939 3.0655032035197545 0.0021730404961168 0.1884740198483208 0.0624047046045847 23 P62942,P26885,Q9Y680,Q02790,Q96AY3,Q9NWM8 6 +Metalloprotease 0.6705057917345131 2.751975830640879 0.0059236892641201 0.4346810394595129 0.0631860188172813 27 Q7Z2K6,P78536,O75844,Q9UIQ6,O95630,P42892,P55786,Q96TA2,Q92905,Q99797,Q9NZ08,Q9BYT8,Q5JRX3,O75976,P09960 15 +Isomerase 0.5308497513332404 2.536941158567968 0.0111825748002638 0.6602600159362013 0.0908382450264113 59 P62942,P26885,Q15125,Q9Y680,Q96PZ0,P48449,Q02790,Q96AY3,Q9NWM8 9 +Carboxypeptidase 0.8846933607292334 2.165367911045634 0.0303595214267731 0.948164084272798 0.1943009371313479 6 Q9H3G5,P42785,Q9HB40,P10619 4 +Dioxygenase 0.6014328133876309 2.099869712711755 0.0357403037005235 0.969617366809026 0.214441822203141 21 O00625,Q32P28,P13674,Q9H6W3,O15460,Q9NVH6 6 +Serine protease 0.7511703964370501 1.995318526984359 0.0460081504983032 0.9891285425052422 0.245376802657617 8 Q16740,P48147 2 +Glycosyltransferase 0.5194822970658253 1.923541030724751 0.0544121387230258 0.9953507672327506 0.2723422963376347 35 Q16739,P43490,O43505,Q13126,O43909,P04062 6 +Host cell receptor for virus entry 0.6217142355662415 1.905323916807248 0.0567379784036738 0.9963296668105912 0.2723422963376347 15 O15118,Q14108,Q8WTV0,P35613 4 +Prenyltransferase 0.819064160113148 1.7857344575512208 0.0741422633985693 0.9993858860609658 0.2847062914505062 5 P53609,P49356 2 +Porin 0.9049166997075976 1.7496222942000552 0.0801835101580956 0.9996724222918548 0.2960621913529686 4 P21796 1 +Cytokine 0.8474923010053607 1.5296140729382457 0.1261122839533497 0.999997602597649 0.4323849735543419 4 P43490 1 +Acyltransferase 0.4641274581981914 1.4756901484118603 0.1400270918485449 0.9999994865030096 0.4635379592227693 34 Q9UJ14,P23786,Q9BWD1,Q8NCC3,Q86UY6 5 +Glycosidase 0.5156728081333446 1.4453638151260657 0.1483557216620752 0.9999997982607652 0.4747383093186407 18 P04062,Q9BTY2,O60502,P06280,O60476,P54802,P08236 7 +Aminopeptidase 0.5751953928106861 1.394549577264823 0.1631517093328622 0.9999999624952388 0.5052440030953154 12 Q9UIQ6,Q9NZ08 2 +Threonine protease 0.86002090444289 1.2389605818235845 0.2153600962864934 0.9999999999226684 0.5851017499278933 3 P28072 1 +Oxidoreductase 0.4100511031207075 1.0428011761357474 0.2970403865169064 0.999999999999998 0.6655500602645906 165 Q9BU89,O75151,Q8N4Q0,Q16836,P30519,Q15392,Q96CU9,P51648,Q15067,Q06136,P48735,Q9H6W3,Q14739,Q9BY49,O00625,Q32P28,P00374,Q15800,Q8N4Q1,P09601,O95881,Q7LG56,Q16850,P78417,Q6DKJ4,P13674,O75874,P35270,Q9NZ01,P49327,Q8NBX0,O95831,Q9UBM7,O75306,Q9UHG3,Q8N0U8,Q8NB78,O15460,Q9NVH6 39 +Monooxygenase 0.796752856283813 1.0062534800314047 0.3142936521235664 0.9999999999999998 0.6655500602645906 3 Q16850,Q9BU89 2 +Guanine-nucleotide releasing factor 0.4208867064104037 0.8848986778235121 0.3762112812013471 1.0 0.7223256599065865 19 P80303 1 +Endonuclease 0.4068386242841871 0.7923641149012435 0.428148397132748 1.0 0.749549301208459 19 Q9UQ84,P51530 2 +Muscle protein 0.5136577042686516 0.6330832612138811 0.5266792725457268 1.0 0.7900189088185902 6 P67936,P09493 2 +Thiol protease 0.3308470458748871 0.383101317221781 0.7016446430018908 1.0 0.9011093060905392 29 Q96FW1,Q9H8M7,P07858,Q9Y4E8,Q96K76 5 +Chloride channel 0.4407246240604703 0.3041911901550386 0.760982236262018 1.0 0.9487570737812172 5 Q96S66 1 +Calcium channel 0.5232942590922722 0.2191930807495705 0.8264996451976234 1.0 1.0 2 Q8NE86 1 +Protein phosphatase inhibitor 0.5192423331328768 0.1860765565875443 0.852384725969836 1.0 1.0 3 Q12972,O43768 2 +Heparin-binding 0.3725490624763583 0.1517232887956544 0.8794051880192704 1.0 1.0 6 P10586 1 +Methyltransferase 0.2779527127446567 0.099127861786996 0.921036750523052 1.0 1.0 47 O96028,Q86VU5,Q08J23,Q9BV86,Q03164,P04818,P21964,Q6P2P2,P22061,Q8IZ69,O60725,Q96RS0 12 +Translocase 0.2848830596413996 0.0623126413036702 0.9503138617364186 1.0 1.0 23 P08183,Q9HD20,Q03518,Q9NQ11,O75306 5 +Hydrolase 0.3126278378928874 0.0623095398851364 0.950316331511064 1.0 1.0 403 P50897,Q969T7,Q16740,Q9H773,Q9UJ14,O75844,Q86YN1,Q9NPH0,Q9UIQ6,P42785,P28074,Q9BQG2,Q9NTK5,Q96FW1,Q9NUJ1,O60502,Q9UMR5,Q96DG6,Q9H0P0,P48147,P28072,P51530,Q9NQE9,P04062,Q8TCT8,O94919,Q9HB40,P42892,Q8NCC3,Q9NZ08,Q9H3G5,P10619,Q8N2K0,O60313,P07099,Q15165,Q9UQ84,Q9NRW3,Q9BTY2,P55786,O95140,Q5JRX3,O75976 43 +Ion channel 0.2933964113793177 0.0050983855527774 0.9959320945056336 1.0 1.0 11 Q96S66,Q9H813,Q96ER9 3 diff --git a/protein_atlas_molecular_function/selections.json b/protein_atlas_molecular_function/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..63b666e74f14484201857eea3e80e5a605ed3999 --- /dev/null +++ b/protein_atlas_molecular_function/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin capping", "Actin-binding", "Activator", "Acyltransferase", "Allosteric enzyme", "Aminoacyl-tRNA synthetase", "Aminopeptidase", "Aminotransferase", "Antibiotic", "Antimicrobial", "Antioxidant", "Aspartyl protease", "Blood group antigen", "Calcium channel", "Calmodulin-binding", "Carboxypeptidase", "Chaperone", "Chloride channel", "Chromatin regulator", "Cyclin", "Cytokine", "DNA-binding", "DNA-directed DNA polymerase", "Decarboxylase", "Developmental protein", "Dioxygenase", "Dipeptidase", "Elongation factor", "Endonuclease", "Excision nuclease", "Exonuclease", "Fungicide", "GTPase activation", "Glycosidase", "Glycosyltransferase", "Growth factor", "Guanine-nucleotide releasing factor", "Helicase", "Heparin-binding", "Hormone", "Host cell receptor for virus entry", "Hydrolase", "Initiation factor", "Integrin", "Ion channel", "Isomerase", "Kinase", "Ligase", "Lyase", "Metalloenzyme inhibitor", "Metalloprotease", "Methyltransferase", "Mitogen", "Monooxygenase", "Motor protein", "Multifunctional enzyme", "Muscle protein", "Myosin", "Nuclease", "Nucleotidyltransferase", "Oxidoreductase", "Peroxidase", "Phospholipase A2 inhibitor", "Porin", "Potassium channel", "Prenyltransferase", "Protease", "Protease inhibitor", "Protein kinase inhibitor", "Protein phosphatase", "Protein phosphatase inhibitor", "Protein synthesis inhibitor", "RNA-binding", "Receptor", "Repressor", "Ribonucleoprotein", "Ribosomal protein", "Rotamase", "Serine esterase", "Serine protease", "Serine protease inhibitor", "Serine/threonine-protein kinase", "Signal transduction inhibitor", "Thiol protease", "Thiol protease inhibitor", "Threonine protease", "Topoisomerase", "Transducer", "Transferase", "Translational shunt", "Translocase", "Tumor antigen", "Tyrosine-protein kinase", "Voltage-gated channel", "rRNA-binding", "tRNA-binding"], "available_proteins": ["AACS", "AAK1", "AAMP", "AARS", "AARS2", "AASDHPPT", "AASS", "ABCB1", "ABCC4", "ABCE1", "ABCF1", "ABHD10", "ABHD11", "ABHD12", "ABHD14B", "ABHD6", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR2", "ACTR3", "ADA", "ADAM17", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPS", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP8", "AKR1A1", "AKR1B1", "AKT1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG13", "ALG5", "ALKBH1", "ALKBH5", "ANKHD1", "ANKRD17", "ANLN", "ANP32B", "ANP32E", "ANXA1", "ANXA2", "APEH", "APEX1", "APOBEC3C", "APRT", "AQR", "ARFGAP1", "ARFGAP3", "ARHGAP1", "ARHGAP17", "ARHGAP35", "ARHGAP5", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL8B", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATE1", "ATF7IP", "ATG3", "ATG4B", "ATIC", "ATL2", "ATL3", "ATP13A1", "ATP13A2", "ATP1A1", "ATP2A2", "ATP2B1", "ATP5B", "ATP6AP2", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "ATRX", "B3GALT6", "B4GALT1", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BANF1", "BAZ1B", "BCAT2", "BCLAF1", "BCOR", "BCS1L", "BDH2", "BIRC6", "BLM", "BLMH", "BLVRA", "BLVRB", "BPNT1", "BPTF", "BRAP", "BRCA1", "BRD2", "BRD4", "BSG", "BTF3", "BUB1", "BUB1B", "BUD23", "BZW1", "BZW2", "C12orf43", "CACTIN", "CAD", "CADM1", "CALD1", "CALR", "CAMK1", "CAMK2G", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CASK", "CASP2", "CASP3", "CAST", "CBL", "CBR1", "CBX3", "CCAR1", "CCAR2", "CCDC47", "CCDC51", "CCDC88A", "CCNA2", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDC25C", "CDC37", "CDC42", "CDC42BPB", "CDC5L", "CDCA7L", "CDIPT", "CDK1", "CDK11B", "CDK4", "CDK5", "CDK5RAP1", "CDK6", "CDKAL1", "CDKN2AIP", "CDS2", "CDX2", "CEBPZ", "CECR2", "CELF1", "CENPB", "CENPE", "CENPU", "CEP55", "CERS2", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHCHD3", "CHCHD4", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK1", "CHEK2", "CHKA", "CHMP1A", "CHORDC1", "CHP1", "CHRAC1", "CHST14", "CHTF18", "CHTF8", "CHTOP", "CHUK", "CIRBP", "CKB", "CKMT1A*", "CLCC1", "CLGN", "CLIC1", "CLIC4", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLSPN", "CLU", "CLUH", "CMAS", "CMBL", "CMPK1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT3", "CNOT7", "CNOT9", "CNP", "COASY", "COLEC12", "COLGALT1", "COMT", "COMTD1", "COPA", "COPS5", "COQ8A", "CORO1B", "CORO1C", "COTL1", "COX2", "COX4I1", "CPD", "CPNE1", "CPOX", "CPPED1", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRYZ", "CS", "CSDE1", "CSK", "CSNK1A1", "CSNK2A2", "CSRP2", "CSTB", "CSTF2", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTDSPL2", "CTH", "CTNNB1", "CTPS1", "CTPS2", "CTSA", "CTSB", "CTSC", "CUL5", "CXorf57", "CYB5R3", "CYC1", "CYFIP1", "CYP20A1", "CYP51A1", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF7", "DCD", "DCP1A", "DCP1B", "DCP2", "DCPS", "DCTD", "DCTPP1", "DCXR", "DDB1", "DDI2", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENND4C", "DENR", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHODH", "DHPS", "DHRS1", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DICER1", "DIEXF", "DIMT1", "DIS3", "DIS3L2", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNA2", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPY30", "DPYSL2", "DRG1", "DRG2", "DST", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EDC3", "EDF1", "EDRF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EFL1", "EGFR", "EGLN1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2AK4", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "EMD", "EMG1", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENSA", "EPB41", "EPB41L2", "EPHX1", "EPHX2", "EPRS", "ERAL1", "ERAP1", "ERCC2", "ERCC3", "ERCC6L", "ERI1", "ERMP1", "ERO1A", "ERP44", "ESD", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXTL3", "F11R", "FAH", "FAHD1", "FAM208A", "FAM213A", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FMR1", "FNTA", "FNTB", "FOXRED1", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCDH", "GCN1", "GDI1", "GDI2", "GDPD1", "GEMIN5", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GGT7", "GLA", "GLB1", "GLDC", "GLO1", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNE", "GNG5", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOT1", "GOT2", "GPAM", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR89B", "GPSM1", "GPT2", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSK3B", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAGH", "HARS2", "HAT1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDLBP", "HEATR1", "HECTD1", "HELLS", "HERC4", "HEXA", "HEXB", "HEXIM1", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMGXB4", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOXD13", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HTATSF1", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDI1", "IFIT5", "IFNGR1", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPA1", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INF2", "INPP4A", "INTS11", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRS4", "ISG20L2", "ISYNA1", "ITCH", "ITGB1", "ITPA", "IVD", "JMJD6", "KARS", "KAT7", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0391", "KIF11", "KIF14", "KIF15", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KRR1", "L2HGDH", "LACTB", "LAMP1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LBR", "LCMT1", "LDHA", "LDHB", "LDLR", "LEMD3", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LNPEP", "LONP1", "LPCAT1", "LPGAT1", "LRP1", "LRPAP1", "LRPPRC", "LRWD1", "LSM14A", "LSM14B", "LSM2", "LSM6", "LSS", "LTA4H", "LTN1", "LUC7L3", "LYAR", "LYPLA1", "LYPLAL1", "M6PR", "MACF1", "MAGED1", "MAGED2", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP1S", "MAP2K1", "MAP2K3", "MAPK1", "MAPK14", "MAPK3", "MARC1", "MARCH5", "MARCKS", "MARK1", "MARK2", "MARS", "MAT2A", "MATR3", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MDH1", "MDH2", "MDN1", "ME2", "MEAF6", "MECP2", "MED1", "MED14", "MED16", "MED21", "MED23", "MED24", "MED4", "MEPCE", "METAP1", "METAP2", "METTL1", "METTL13", "METTL16", "METTL3", "MFN1", "MFN2", "MGAT1", "MGEA5", "MGME1", "MGST2", "MGST3", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MKRN2", "MMAB", "MMS19", "MOGS", "MORC2", "MORF4L1", "MOV10", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPRIP", "MPST", "MRC2", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL22", "MRPL23", "MRPL28", "MRPL3", "MRPL37", "MRPL39", "MRPL4", "MRPL40", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL50", "MRPL55", "MRPL58", "MRPL9", "MRPS10", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MSH2", "MSH3", "MSH6", "MSI1", "MSMO1", "MTA1", "MTA2", "MTAP", "MTERF3", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR2", "MTOR", "MTPAP", "MTR", "MTSS1L", "MUT", "MVK", "MYBBP1A", "MYCBP2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA40", "NAA50", "NACC1", "NADK2", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L4", "NARS", "NAT10", "NAXE", "NCL", "NCOA5", "NCOR1", "ND5", "NDUFAF2", "NDUFAF4", "NDUFAF7", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEK9", "NELFA", "NELFCD", "NELFE", "NES", "NFKB1", "NFS1", "NHP2", "NIFK", "NIP7", "NIPBL", "NISCH", "NIT2", "NKRF", "NKTR", "NLN", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOB1", "NOC2L", "NOL11", "NOL6", "NOL8", "NOL9", "NONO", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NRDC", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSUN2", "NSUN5", "NSUN6", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDCD1", "NUDT1", "NUDT12", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUFIP2", "NUP153", "NUP98", "NXF1", "NXN", "OAT", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC3", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OXCT1", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAK1", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PCNT", "PCYOX1", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK3", "PDLIM7", "PDXDC1", "PDXK", "PEBP1", "PECR", "PELO", "PELP1", "PEPD", "PFAS", "PFDN1", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGGT1B", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB2", "PHF2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PI4K2A", "PI4KA", "PI4KB", "PIGG", "PIGK", "PIGL", "PIK3C2A", "PIK3C3", "PIK3R4", "PIN1", "PIN4", "PIP4K2B", "PIR", "PISD", "PITHD1", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCB3", "PLCG1", "PLD3", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PMPCB", "PMS1", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPO", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR2B", "POLR2G", "POLR3A", "POLR3C", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAT", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R8", "PPP3CA", "PPP5C", "PPP6C", "PPT1", "PPT2", "PPWD1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKACA", "PRKCD", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF31", "PRPF4B", "PRPF8", "PRPS1", "PRPS2", "PSAT1", "PSIP1", "PSMB5", "PSMB6", "PSMB7", "PSMD10", "PSMD14", "PSME4", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN23", "PTPN9", "PTPRF", "PTRH2", "PTRHD1", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PYCR1", "PYCR2", "PYGB", "PYGL", "PYM1", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "RAB10", "RAB11B", "RAB18", "RAB1A", "RAB1B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RABGAP1", "RABGGTA", "RABGGTB", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD50", "RALA", "RALY", "RANBP1", "RANBP2", "RANGAP1", "RANGRF", "RAP1GDS1", "RAPGEF2", "RAPGEF6", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM47", "RBM5", "RBM8A", "RBMX", "RBPMS", "RCC1", "RCC2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "RECQL5", "REXO2", "REXO4", "RFC1", "RFC3", "RHOA", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIOX1", "RIOX2", "RIPK1", "RMND5A", "RNASEH2A", "RNASET2", "RNF14", "RNF20", "RNF219", "RNF220", "RNF40", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP1", "RPF1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPP30", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAS2", "RREB1", "RRM1", "RRM2", "RRM2B", "RRP1B", "RRP8", "RRP9", "RSF1", "RTCA", "RTCB", "RTF1", "RTRAF", "RUVBL1", "RUVBL2", "SACM1L", "SACS", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAP130", "SAP18", "SARNP", "SARS", "SARS2", "SART3", "SCAF1", "SCAF4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SDHA", "SDHB", "SEC11A", "SEC61A1", "SEC63", "SELENBP1", "SENP3", "SEPHS1", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD7", "SF1", "SF3B1", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SGPL1", "SGTA", "SHMT1", "SHMT2", "SHTN1", "SIGMAR1", "SIN3A", "SIRT1", "SKIV2L", "SKIV2L2", "SLC1A5", "SLC27A4", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMAP2", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCE1", "SMCHD1", "SMN1*", "SMPD4", "SMS", "SND1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPATA5", "SPCS2", "SPEN", "SPHK2", "SPOUT1", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SRCAP", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "STAMBP", "STAT1", "STAT3", "STAU1", "STK26", "STK4", "STMN1", "STRBP", "STRN", "STT3A", "STT3B", "STUB1", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYNCRIP", "SYNE1", "SYNE2", "TACO1", "TAF15", "TALDO1", "TAMM41", "TAP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D17", "TBC1D2B", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCA", "TBCB", "TBCC", "TBCD", "TBCE", "TBK1", "TBL1XR1", "TCEA1", "TCERG1", "TCP1", "TDRD7", "TDRKH", "TECR", "TERF2", "TERF2IP", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFRC", "TGS1", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM50", "TIMM8A", "TIMM8B", "TIMM9", "TIMMDC1", "TJP1", "TK1", "TKFC", "TKT", "TMCO1", "TMEM109", "TMEM126B", "TMEM206", "TMEM63A", "TMF1", "TMLHE", "TMOD1", "TMOD3", "TMTC3", "TMX3", "TOMM22", "TOMM34", "TOMM40", "TOP1", "TOP2A", "TOP2B", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPI1", "TPM1", "TPM3", "TPM4", "TPMT", "TPP1", "TPP2", "TRA2A", "TRA2B", "TRAP1", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIO", "TRIP12", "TRIR", "TRMT1", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TRMU", "TROVE2", "TRUB1", "TSC2", "TSFM", "TSN", "TSNAX", "TTF2", "TTK", "TTYH3", "TUFM", "TWF1", "TWF2", "TWNK", "TXNDC12", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE2T", "UBE3A", "UBE3C", "UBE4A", "UBLCP1", "UBP1", "UBR1", "UBR4", "UBR5", "UBTF", "UCHL5", "UCK2", "UFL1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCRFS1", "UROD", "USP10", "USP11", "USP14", "USP15", "USP24", "USP28", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTRN", "UXT", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIRMA", "VKORC1L1", "VPS4A", "VPS4B", "VRK1", "VRK2", "WARS", "WARS2", "WASL", "WDHD1", "WDR1", "WDR18", "WDR43", "WDR48", "WDR5", "WNK1", "WNK2", "WRAP53", "WTAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPOT", "XRCC5", "XRCC6", "XRN2", "YAP1", "YARS", "YARS2", "YBX1", "YBX3", "YEATS4", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF1", "YTHDF2", "YTHDF3", "ZADH2", "ZC3H14", "ZC3HAV1", "ZCCHC11", "ZCCHC3", "ZCRB1", "ZFR", "ZMPSTE24", "ZNF24", "ZNF281", "ZNF318", "ZNF326", "ZNF512B", "ZNF638", "ZRANB2"], "leading_proteins": ["ABCB1", "ABHD10", "ABHD12", "ACAT2", 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a/protein_atlas_protein_class/consensus.joblib b/protein_atlas_protein_class/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..4252018d25c235b233f13c9d630922ccee4b249e --- /dev/null +++ b/protein_atlas_protein_class/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:dd98eae90fad7b90cd064ce0b8d2b849426ab91faa8ae47de90aaf6369b1dbc3 +size 77096 diff --git a/protein_atlas_protein_class/df_merge.tsv b/protein_atlas_protein_class/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..4b68dc51775539bd54c6f5278379b805a11b150b --- /dev/null +++ b/protein_atlas_protein_class/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Predicted membrane proteins 179 553 6.297804666459814 3.0189059816240624e-10 204.61650485436897 563.8058252427185 3.080866334016093 0.3028099075873978 81.17076282318972 73.52280648113661 4.068861305085399 0.4187410497068249 0.0001378881574353 0.0003730486519231 3.3299360941879286e-06 2.6181931729919413e-14 6.918326632085858e-12 +Predicted secreted proteins 19 52 2.871453460400603 0.0040858894126623 15.29368932038835 51.737864077669904 1.393291060716792 0.256881456821794 5.463351773637434 6.9884942404294375 1.5049506819867255 0.3173597508227758 0.0199003860349782 0.0423139640945197 0.0156096381318318 0.0315294125525574 0.0677777370039816 diff --git a/protein_atlas_protein_class/metrics.json b/protein_atlas_protein_class/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..5c2a55b7c7020647a3ea92a8d74d7e7f202e5574 --- /dev/null +++ b/protein_atlas_protein_class/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3329, + "annotations_size": 20, + "title": "Average number of proteins per term", + "value": 530.0 +} \ No newline at end of file diff --git a/protein_atlas_protein_class/paths.json b/protein_atlas_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..c0e2eef0a54a2317b2b68fd7444abb017086c467 --- /dev/null +++ b/protein_atlas_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_protein_class/fragment/C342/C342_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_protein_class/result.tsv b/protein_atlas_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..221aef8751b33d80493e12ce25250e7ab0f1c0a8 --- /dev/null +++ b/protein_atlas_protein_class/result.tsv @@ -0,0 +1,11 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Predicted membrane proteins 0.5613934420716239 6.297804666459814 3.0189059816240624e-10 6.0378119659319185e-09 6.037811983248124e-09 553 P62942,Q86Y82,Q9H6H4,Q5KU26,P37268,P15260,P30519,Q15392,Q9UIQ6,Q8WTV0,Q9NR77,Q9NS69,Q9NX40,Q5BJF2,O43731,Q96ER9,Q96JJ7,Q9Y6N1,P00846,Q14739,Q70HW3,Q7RTS9,Q567V2,P24390,P50402,P15291,O00264,Q14534,Q99595,Q9Y619,Q9NPR9,O43772,Q6NT16,P09601,P41440,O60725,O43169,Q8NBN3,Q9BSK2,Q8IXU6,Q8TCT8,Q15629,Q5VW38,Q9NX00,P42892,Q8NCC3,O75071,O95470,O95563,Q8N2K0,Q9Y639,Q9Y282,Q15125,Q9NR28,Q92804,Q16799,O95831,O75964,Q02978,Q86XL3,Q03518,O00461,O43657,O15173,Q15363,Q3SXM5,P43307,Q96A26,Q9UJ14,Q9Y2R0,O75844,O95197,Q99523,Q9BXS4,Q9HD20,Q8NCH0,Q06136,Q9Y487,Q14108,Q07065,Q8IZA0,O43676,Q93050,Q96G23,Q9HD45,Q8IWV7,Q15800,Q9UDW1,O43909,O43752,Q7LG56,Q16850,Q99720,Q15070,Q15041,O94919,Q9H6K4,Q9NZ01,P49257,Q9UDX5,Q9BU23,Q9HC07,P42356,O15270,P35613,Q9P260,Q9P2W9,P38435,Q9UBM7,P09493,O75306,O14925,Q8N0U8,Q9BTX1,O95140,O75976,O95674,Q16739,Q9H061,Q6UW68,Q86YN1,P12235,Q8IV08,Q9NPL8,Q9NQ11,Q96S66,P10321,P42858,Q5VV42,O75880,O60925,Q8N511,Q9H1E5,Q9BVK6,Q06210,P67812,Q969V3,Q8NBX0,Q96QD8,Q5T8D3,P20645,Q6P4A7,Q9H3K2,Q8N5M9,Q86Y39,O60476,Q9Y6C9,Q99805,O96005,Q9UBX3,Q9P035,P51648,O15118,O15360,O75438,O95168,Q16134,Q9UBG0,P53985,A1L0T0,Q9Y262,Q92734,Q8N2F6,Q6NUK4,Q52LJ0,P08183,Q7Z2K6,Q9BXK5,Q96PC5,Q9BUN8,Q9HBM0,Q96TA2,Q7KZN9,P78536,P02786,Q9H813,P16615,Q9Y5M8,Q96KA5 179 +Predicted secreted proteins 0.5849364647977605 2.871453460400603 0.0040858894126623 0.0786222633714458 0.040858894126623 52 P14174,P43490,P11047,Q8WUJ1,O60888,Q9UMX5,P80303,P84157,O94919,Q02818,Q9HB40,P07858,O75718,Q9NZ08,Q15165,P02786,Q9BTY2,Q9UM22,P04083 19 +Enzymes 0.3179073138444879 1.9082014618676504 0.056365182766445 0.6866143306946353 0.2699655363350368 958 P62942,Q969T7,O15217,Q16740,Q9H773,P43490,Q8N4Q0,P37268,Q9BV86,Q9NPH0,P30519,Q15392,Q9UIQ6,P42785,Q96AY3,P48735,Q14739,P26885,O00625,Q32P28,P00374,Q96FW1,Q9NUJ1,O60502,Q9BWD1,P09601,O60725,Q86UY6,P49721,P28072,P19474,Q8TCT8,P48449,P23786,O75874,Q9HB40,P42892,Q02790,Q13126,Q8NCC3,P35270,Q9NZ08,Q9H3G5,P10619,O95470,Q8N2K0,P07099,Q15125,P49356,Q9UHG3,P53609,Q5JRX3,Q9NVH6,P50897,P28070,P53701,Q9UJ14,O75844,Q16836,Q15067,Q8NCH0,Q06136,P28074,Q9BQG2,Q9H6W3,P35790,Q96G23,Q9Y680,Q8IWV7,P20618,P17812,Q15800,Q9H0P0,Q9NWM8,Q13451,O43909,P48147,P51530,Q7LG56,P04062,Q16850,P78417,P13674,P34896,P31749,Q9BRR6,Q9NZ01,P42356,O15270,O60313,Q15165,Q9NRW3,P38435,Q9UBM7,Q9BTY2,O75306,P55786,Q8N0U8,Q8NB78,Q15120,O15460,O75976,O95674,P14174,Q16739,P25786,Q9NSE4,Q86YN1,Q8IV08,P34897,Q9BY49,P60900,Q9BRF8,Q4J6C6,Q5VV42,O95881,Q9Y5P6,Q8NI60,Q6DKJ4,Q06210,P11233,P67812,P07858,O60566,O14757,Q9Y5S2,Q9UBS8,P49327,Q9BYT8,P53611 130 +Transporters 0.4374552777377986 1.8283877130796808 0.0674913840837592 0.7527951066199499 0.2699655363350368 366 P62942,Q8WTV0,Q9NR77,Q5BJF2,Q70HW3,P24390,Q9Y619,O43772,Q6NT16,P41440,Q9BSK2,P45880,Q8IXU6,Q9H2D1,Q8TCT8,Q15629,Q5VW38,O95563,Q9Y639,Q16799,Q02978,Q03518,Q15363,O75844,Q99523,Q9BXS4,Q9HD20,P07602,Q14108,O95373,Q07065,Q93050,O43752,Q99720,Q15070,P31749,P49257,Q9HC07,O60313,P35613,O60343,Q9BTX1,O95140,Q16739,Q9H061,Q6UW68,P12235,Q9NQ11,Q96S66,Q92973,Q96L92,Q8N511,Q9HAV4,Q969V3,Q9NQZ5,P20674,Q96QD8,Q5T8D3,P20645,P04083,Q6P4A7,Q01469,Q9Y6C9,Q99805,O96005,Q9UBX3,O15118,O15397,P53985,P08183,Q96PC5,Q9BUN8,Q9HBM0,P09132,O75340,Q9Y512,P78536,P04080,P02786 79 +Metabolic proteins 0.3071053829862342 1.2818341964119724 0.1999008154734689 0.988442163264077 0.6663360515782298 913 P62942,Q969T7,O15217,Q9H773,P43490,Q8N4Q0,P37268,Q9NPH0,P30519,Q15392,Q8WTV0,Q96AY3,P48735,P00846,Q14739,Q70HW3,P26885,Q9Y619,P00374,O43772,O60502,Q9BWD1,P09601,P41440,O60725,Q86UY6,Q9H2D1,P48449,P23786,O75874,Q02790,Q13126,Q8NCC3,P35270,P10619,O95470,O95563,Q8N2K0,P07099,Q15125,O75964,Q02978,P49356,Q9UHG3,Q9NVH6,P50897,P53701,Q9UJ14,O75844,P30154,Q16836,Q15067,Q8NCH0,P07602,Q06136,P30153,Q9Y487,Q9BQG2,P35790,O14949,O43676,Q93050,Q96G23,Q9Y680,Q8IWV7,O43505,P17812,Q15800,Q9UDW1,Q9UMR5,Q9H0P0,Q9NWM8,Q13451,O43909,P48147,Q7LG56,P04062,Q16850,P78417,P13674,P34896,P31749,Q9BRR6,Q9NZ01,P42356,O15270,Q15165,Q9UBM7,Q9BTY2,O75306,P55786,Q9BTX1,Q15120,O15460,O95674,P14174,Q16739,Q86YN1,P12235,Q8IV08,P34897,Q9BY49,Q9NR33,Q14181,Q9Y5P6,Q06210,P67812,P07858,O60566,O14757,Q9Y5S2,Q9UBS8,P49327,Q9BYT8,Q06203,Q9NQZ5,Q8NBX0,P20674,Q96QD8,O43924,Q86Y39,Q01469,P28482,O60476,Q9UBX3,Q9P035,P51648,O15118,O75438,O95168,Q16134,Q8NFF5,Q9NRF8,P53985,P17900,O75648,Q92820,Q7LGA3,Q14914,P21964,Q6P2P2,Q9Y237,Q96K76,Q13510,P09960,P08183,O96028,O95071,Q9Y6M9,Q9Y2B2 150 +Potential drug targets 0.2996996910664418 1.0460511503040686 0.2955374171485629 0.9990939365432634 0.8443926204244656 501 P50897,P14174,P28070,Q16740,P53701,Q9H061,O75844,P37268,Q9NSE4,Q99523,Q15392,Q8IV08,Q15067,Q8NCH0,P07602,Q06136,Q9NQ11,Q96AY3,Q14739,Q70HW3,Q96S66,Q14108,Q32P28,Q9Y619,Q8IWV7,O43772,P17812,Q15800,Q4J6C6,Q5VV42,Q9H0P0,P09601,Q9NWM8,O43909,P51530,P04062,Q8N511,Q9Y5P6,Q9H2D1,Q8NI60,P48449,Q6DKJ4,Q06210,P31749,P42892,P07858,Q13126,P35270,Q9NZ01,P49257,P10619,O95470,Q9HC07,P42356,Q8N2K0,O15270,P07099,O60313,O60343,Q15125,Q02978,Q9UBM7,Q03518,O75306,Q15120,O95140,O15460,Q9NVH6 68 +FDA approved drug targets 0.3619732526772211 0.708060977309378 0.4789073913560673 0.9999978207941276 0.8707407115564859 126 P62942,Q16739,P15260,Q16836,P12235,Q96ER9,P28074,P48735,Q16134,P42574,P00374,P20618,Q9NR33,P21964,P49721,Q7LG56,Q16850,Q99720,P23786,O75874,Q9Y2I1,P49327,P02786,P38435,Q96QD8,P49356,P20645,P16615,P04083,Q8N0U8,P28482 31 +Citric acid cycle related proteins 0.3234734142612007 0.3124572232813085 0.7546930676462589 0.9999999999993774 1.0 25 P48735 1 +CD markers 0.3069012578549239 0.1726896921633985 0.8628953465240738 1.0 1.0 19 P08183,P78536,P02786,Q9UBG0,P35613 5 +Candidate cardiovascular disease genes 0.3148950301511837 0.0886649749432901 0.9293481688131124 1.0 1.0 12 Q15165,P09493 2 diff --git a/protein_atlas_protein_class/selections.json b/protein_atlas_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..b787838fa35961739260ff3af5f04debcde6f56e --- /dev/null +++ b/protein_atlas_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Blood group antigen proteins", "CD markers", "Cancer-related genes", "Candidate cardiovascular disease genes", "Citric acid cycle related proteins", "Disease related genes", "Enzymes", "FDA approved drug targets", "Human disease related genes", "Metabolic proteins", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Predicted secreted proteins", "RAS pathway related proteins", "RNA polymerase related proteins", "Ribosomal proteins", "Transcription factors", "Transporters"], "available_proteins": ["AAAS", "AACS", "AAGAB", "AAK1", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD11", "ABHD12", "ABHD14B", "ABHD6", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ADA", "ADAM17", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKT1", "AKT1S1", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG13", "ALG5", "ALKBH1", "ALKBH5", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APC", "APEH", "APEX1", "API5", "APMAP", "APOBEC3C", "APOO", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP3", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGAP35", "ARHGAP5", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL6IP5", "ARL8B", "ARMC1", "ARMC10", "ARMC6", "ARMC9", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARVCF", "ASAH1", "ASB6", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATE1", "ATF7IP", "ATG3", "ATG4B", "ATG9A", "ATIC", "ATL2", "ATL3", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATRX", "ATXN10", "ATXN2", "ATXN2L", "AUP1", "B3GALT6", "B4GALT1", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BCAP31", "BCAS2", "BCAT2", "BCCIP", "BCL2L12", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BDH2", "BICD2", "BIRC6", "BLM", "BLMH", "BLOC1S1", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOD1L1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAP", "BRAT1", "BRCA1", "BRD2", "BRD4", "BRI3BP", "BRIX1", "BROX", "BSG", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C12orf73", "C14orf2", "C15orf39", "C19orf25", "C19orf70", "C1QBP", "C1orf122", "C1orf123", "C1orf35", "C1orf50", "C20orf27", "C21orf59", "C2CD5", "C2orf49", "C5orf15", "C5orf51", "CAB39", "CACTIN", "CACUL1", "CACYBP", "CAD", "CADM1", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAP2", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CASK", "CASP2", "CASP3", "CAST", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC124", "CCDC138", "CCDC22", "CCDC43", "CCDC47", "CCDC51", "CCDC6", "CCDC86", "CCDC88A", "CCDC93", "CCDC94", "CCDC97", "CCNA2", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC23", "CDC25C", "CDC27", "CDC37", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP3", "CDK6", "CDKAL1", "CDKN2AIP", "CDR2L", "CDS2", "CDV3", "CDX2", "CEBPZ", "CECR2", "CELF1", "CENPB", "CENPE", "CENPI", "CENPU", "CENPV", "CEP170", "CEP250", "CEP44", "CEP55", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHCHD4", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP4A", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHP1", "CHRAC1", "CHST14", "CHTF18", "CHTF8", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLN6", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTA", "CLTC", "CLU", "CLUH", "CMAS", "CMBL", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNOT1", "CNOT11", "CNOT3", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG2", "COG3", "COG7", "COIL", "COLEC12", "COLGALT1", "COMMD1", "COMMD10", "COMMD2", "COMMD7", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "CORO1B", "CORO1C", "COTL1", "COX11", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTDSPL2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CTTNBP2NL", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC22", "CWF19L1", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF7", "DCAF8", "DCAKD", "DCD", "DCP1A", "DCP1B", "DCP2", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENND4C", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHODH", "DHPS", "DHRS1", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DIS3L2", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTL", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFL1", "EFTUD2", "EGFR", "EGLN1", "EHBP1", "EHD1", "EHD4", "EHMT2", "EIF2A", "EIF2AK2", "EIF2AK4", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP4", "EMC1", "EMC2", "EMC3", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENSA", "EPB41", "EPB41L2", "EPB41L5", "EPDR1", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6B", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXTL3", "EZR", "F11R", "FABP5", "FAF1", "FAF2", "FAH", "FAHD1", "FAM114A1", "FAM114A2", "FAM118B", "FAM160A2", "FAM162A", "FAM177A1", "FAM208A", "FAM213A", "FAM49B", "FAM50A", "FAM83D", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FBL", "FBXO22", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNBP4", "FNDC3A", "FNTA", "FNTB", "FOXRED1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLM", "GCN1", "GDAP1", "GDAP2", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GEMIN8", "GET4", "GFM1", "GFPT1", "GGA1", "GGCT", "GGCX", "GGH", "GGT7", "GHDC", "GHITM", "GID4", "GID8", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNE", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM1", "GOLPH3", "GOLPH3L", "GOLT1B", "GOPC", "GORASP2", "GOT1", "GOT2", "GPAM", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR108", "GPR89B", "GPS1", "GPSM1", "GPT2", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSDME", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTSE1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAGH", "HARS2", "HAT1", "HAUS1", "HAUS2", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HELLS", "HERC4", "HEXA", "HEXB", "HEXIM1", "HGH1", "HGS", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIP1", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOXD13", "HP1BP3", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA6", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HUS1", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IER3IP1", "IFIT5", "IFNGR1", "IFT27", "IFT88", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "IKBKB", "IKBKG", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPA1", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS11", "INTS12", "INTS13", "INTS14", "INTS3", "INTS7", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRGQ", "IRS4", "ISCU", "ISG20L2", "ISOC1", "ISOC2", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITSN2", "IVD", "IWS1", "JAGN1", "JMJD6", "JPT2", "JUP", "KARS", "KAT7", "KCTD12", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1211", "KIAA1468", "KIAA2013", "KIF11", "KIF14", "KIF15", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "L2HGDH", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCMT1", "LDHA", "LDHB", "LDLR", "LDLRAP1", "LEMD2", "LEMD3", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRCH2", "LRP1", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRWD1", "LSM12", "LSM14A", "LSM14B", "LSM2", "LSM6", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYPLAL1", "LZIC", "LZTFL1", "LZTS2", "M6PR", "MACF1", "MAD1L1", "MAGED1", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K3", "MAP4", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARK1", "MARK2", "MARS", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MEAF6", "MECP2", "MED1", "MED14", "MED16", "MED21", "MED23", "MED24", "MED4", "MEPCE", "METAP1", "METAP2", "METTL1", "METTL13", "METTL16", "METTL3", "MFAP1", "MFF", "MFN1", "MFN2", "MFSD10", "MFSD5", "MGAT1", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MICALL1", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MKLN1", "MKRN2", "MLEC", "MMAB", "MMGT1", "MMS19", "MOB4", "MOGS", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRC2", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL22", "MRPL23", "MRPL28", "MRPL3", "MRPL37", "MRPL39", "MRPL4", "MRPL40", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL50", "MRPL55", "MRPL58", "MRPL9", "MRPS10", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTERF3", "MTFP1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR2", "MTOR", "MTPAP", "MTR", "MTSS1L", "MTX1", "MTX2", "MTX3", "MUT", "MVK", "MXRA7", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA16", "NAA35", "NAA40", "NAA50", "NACC1", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCDN", "NCKAP1", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "ND5", "NDC1", "NDC80", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEFL", "NEFM", "NEK9", "NELFA", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NFATC2IP", "NFKB1", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NMD3", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NRDE2", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSUN2", "NSUN5", "NSUN6", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUB1", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PATL1", "PAXIP1", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNP", "PCNT", "PCYOX1", "PDAP1", "PDCD11", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXDC1", "PDXK", "PDZD8", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN1", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGGT1B", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF2", "PHF3", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PI4KB", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIH1D1", "PIK3C2A", "PIK3C3", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2B", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCB3", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNISR", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPO", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPFIA1", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKAR2B", "PRKCD", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF39", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN23", "PTPN9", "PTPRF", "PTRH2", "PTRHD1", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "PYM1", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABEP1", "RABEPK", "RABGAP1", "RABGGTA", "RABGGTB", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RANGRF", "RAP1GDS1", "RAPGEF2", "RAPGEF6", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM47", "RBM5", "RBM8A", "RBMX", "RBPMS", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "RECQL5", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "RETREG3", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOX1", "RIOX2", "RIPK1", "RMDN1", "RMND5A", "RNASEH2A", "RNASEH2B", "RNASET2", "RNF14", "RNF20", "RNF219", "RNF220", "RNF40", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RPUSD2", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCA", "RTCB", "RTF1", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SAAL1", "SACM1L", "SACS", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SASS6", "SBDS", "SBNO1", "SCAF1", "SCAF11", "SCAF4", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCYL2", "SDAD1", "SDCBP", "SDF2L1", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD7", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL", "SH3BGRL2", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIN3A", "SIRT1", "SKA1", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A5", "SLC25A6", "SLC27A4", "SLC30A7", "SLC35B2", "SLC35F2", "SLC38A2", "SLC3A2", "SLC4A1AP", "SLC6A15", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SLU7", "SMAP1", "SMAP2", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC6", "SMCHD1", "SMG8", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SNAP23", "SNAP29", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC24", "SPC25", "SPCS2", "SPDL1", "SPECC1", "SPECC1L", "SPEN", "SPHK2", "SPNS1", "SPOUT1", "SPPL2A", "SPR", "SPRYD4", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRBD1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX4", "STX6", "STX7", "STX8", "STXBP2", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE1", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACC3", "TACO1", "TADA3", "TAF15", "TAGLN2", "TALDO1", "TAMM41", "TANGO6", "TAP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D17", "TBC1D2B", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCA", "TBCB", "TBCC", "TBCD", "TBCE", "TBK1", "TBL1XR1", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TCP11L1", "TDRD7", "TDRKH", "TECR", "TELO2", "TERF2", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGS1", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM17A", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TIMM9", "TIMMDC1", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLN1", "TM9SF2", "TM9SF3", "TM9SF4", "TMA16", "TMA7", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM11", "TMEM126A", "TMEM126B", "TMEM160", "TMEM165", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM206", "TMEM209", "TMEM214", "TMEM230", "TMEM245", "TMEM30A", "TMEM33", "TMEM43", "TMEM59", "TMEM63A", "TMEM87A", "TMEM97", "TMF1", "TMLHE", "TMOD1", "TMOD3", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOM1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1AIP1", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPMT", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIO", "TRIP12", "TRIP13", "TRIR", "TRMT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMU", "TROVE2", "TRUB1", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPYL1", "TSR1", "TSR2", "TTC1", "TTC19", "TTC26", "TTC27", "TTC28", "TTC37", "TTC38", "TTC4", "TTF2", "TTI1", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXN2", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAP2", "UBAP2L", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE2T", "UBE3A", "UBE3C", "UBE4A", "UBL5", "UBLCP1", "UBP1", "UBQLN1", "UBQLN2", "UBQLN4", "UBR1", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "UHRF1BP1", "UMPS", "UNC119B", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "UROD", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP15", "USP24", "USP28", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "UXT", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VPS13A", "VPS18", "VPS25", "VPS26A", "VPS26B", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37C", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK2", "VTA1", "VTI1B", "WAPL", "WARS", "WARS2", "WASHC3", "WASHC5", "WASL", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR36", "WDR4", "WDR41", "WDR43", "WDR45B", "WDR46", "WDR48", "WDR5", "WDR6", "WDR61", "WDR70", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WNK1", "WNK2", "WRAP53", "WRAP73", "WTAP", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YAP1", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YEATS4", "YIF1A", "YIPF4", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF1", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM2", "ZMYM4", "ZMYND8", "ZNF24", "ZNF281", "ZNF318", "ZNF326", "ZNF512B", "ZNF622", "ZNF638", "ZPR1", "ZRANB2", "ZSWIM8", "ZW10", "ZWILCH", "ZYX"], "leading_proteins": ["ABCB1", "ABHD10", "ABHD12", "ACAT2", "ACBD5", "ACOX1", "ACP6", "ADAM17", "ADPGK", "AIFM1", "AKT1", "ALDH3A2", "ANKLE2", "ANXA1", "APOBEC3C", "ARL6IP1", "ARMC10", "ASAH1", "ATP13A1", "ATP13A2", "ATP2A2", "ATP5L", "ATP6", "ATP6V0A1", "ATP6V0A2", "B4GALT1", "B4GAT1", "BCL2L13", "BSG", "BUB1B", "CASP3", "CCDC51", "CDC42BPB", "CDKAL1", "CDS2", "CERS2", "CHEK1", "CHKA", "CHST14", "CKAP4", "CLCC1", "CLPP", "CLPTM1", "CLPTM1L", "COA3", "COLEC12", "COMT", "COQ8A", "COX11", "COX15", "COX5A", "CPD", "CPPED1", "CPT2", "CPVL", "CRTAP", "CSTB", "CTPS1", "CTPS2", "CTSA", "CTSB", "CUTA", "CYB5B", "CYB5D2", "CYP51A1", "DCTPP1", "DERL1", "DHCR24", "DHCR7", "DHFR", "DIABLO", "DNA2", "DOLPP1", "DYM", "EBP", "ECE1", "EFCAB14", "EIF3L", "EMD", "ENDOD1", "EPDR1", "EPHX1", "ERAP1", "ERGIC3", "ERMP1", "ETFDH", "EXTL3", "FABP5", "FAM162A", "FAM98B", "FANCA", "FASN", "FDFT1", "FKBP10", "FKBP14", "FKBP1A", "FKBP2", "FKBP4", "FKBP5", "FKBP7", "FLAD1", "FNTB", "FUCA2", "GBA", "GFPT1", "GGCX", "GGH", "GGT7", "GHITM", "GM2A", "GMPPB", "GOLIM4", "GPR107", "GPR108", "GSTA4", "GSTO1", "HACD3", "HADH", "HCCS", "HLA-C", "HMOX1", "HMOX2", "HS2ST1", "HSDL1", "HTT", "IARS2", "ICMT", "IDH1", "IDH2", "IFNGR1", "ILVBL", "IPO7", "IPO8", "JAGN1", "KDELR1", "KDELR3", "KDM1B", "KDSR", "KIAA0319L", "KIAA1468", "LAMC1", "LBR", "LMAN1", "LMF2", "LNPEP", "LSS", "LTA4H", "M6PR", "MAN1A2", "MAPK1", "MFN2", "MGEA5", "MIA2", "MIF", "MPC2", "MPV17L2", "MRC2", "MSMO1", "MTAP", "MTCH2", "MTFP1", "MXRA7", "NAA40", "NAMPT", "NCLN", "NDC1", "NDUFA11", "NDUFB1", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS2", "NENF", "NISCH", "NLN", "NPC1", "NPEPPS", "NPTN", "NSD2", "NT5C3A", "NT5C3B", "NTMT1", "NUCB1", "NUCB2", "NUDT12", "NXN", "OCIAD1", "OPA1", "OPA3", "OTUB1", "OXA1L", "P3H1", "P4HA1", "P4HA2", "PCYOX1", "PDCD6", "PDE6D", "PDK3", "PECR", "PFDN1", "PGGT1B", "PGRMC1", "PGRMC2", "PI4KA", "PIGL", "PIN4", "PIR", "PITRM1", "PLA2G15", "PLD3", "POLA2", "POLE4", "PON2", "PPAT", "PPP2R1A", "PPP2R1B", "PPT1", "PPT2", "PRCP", "PREP", "PREPL", "PRMT9", "PSAP", "PSMA1", "PSMA6", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PTGR1", "PXMP2", "RABGGTB", "RALA", "REEP3", "REEP4", "RIOX1", "RNF14", "RRM2B", "RTN1", "RTN3", "SAMM50", "SCARB1", "SCARB2", "SCCPDH", "SCO1", "SCPEP1", "SEC11A", "SFXN4", "SGPL1", "SHMT1", "SHMT2", "SIGMAR1", "SLC16A1", "SLC18B1", "SLC19A1", "SLC25A10", "SLC25A11", "SLC25A15", "SLC25A20", "SLC25A26", "SLC25A32", "SLC25A33", "SLC25A4", "SLC35F2", "SLC38A2", "SNX27", "SORT1", "SPPL2A", "SPR", "SPTLC2", "SQLE", "SRP19", "SRPRB", "SSR1", "STARD7", "STX12", "STX18", "STX6", "TAF15", "TAP1", "TBC1D4", "TECR", "TFG", "TFRC", "TIMM17A", "TIMM23", "TIMMDC1", "TM9SF2", "TM9SF3", "TMED2", "TMED9", "TMEM126A", "TMEM160", "TMEM165", "TMEM199", "TMEM205", "TMEM206", "TMEM59", "TMEM87A", "TMEM97", "TMLHE", "TMX3", "TMX4", "TNPO1", "TOMM22", "TPM1", "TRAM1", "TRIM21", "TRMU", "TSPAN6", "TXNDC12", "UBR1", "UBR5", "UGCG", "UQCR10", "UQCRQ", "USP47", "VDAC2", "VEZT", "VKORC1L1", "XPO5", "YME1L1", "ZADH2", "ZMPSTE24"]} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/advanced/idx2term.json b/protein_atlas_subcellular_location_all/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/protein_atlas_subcellular_location_all/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git 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0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/protein_atlas_subcellular_location_all/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/protein_atlas_subcellular_location_all/metrics.json b/protein_atlas_subcellular_location_all/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..e7f656aba659b1413965057b35b9890f8132134a --- /dev/null +++ b/protein_atlas_subcellular_location_all/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3329, + "annotations_size": 34, + "title": "Average number of proteins per term", + "value": 151.7941176470588 +} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/paths.json b/protein_atlas_subcellular_location_all/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..e68021734690b9f515ba4fd8701ba97049c32bf8 --- /dev/null +++ b/protein_atlas_subcellular_location_all/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_subcellular_location_all/fragment/C342/C342_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/result.tsv b/protein_atlas_subcellular_location_all/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..dad4e6474cab3a28c916c81bf5f93b76dd6826fc --- /dev/null +++ b/protein_atlas_subcellular_location_all/result.tsv @@ -0,0 +1,12 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Endoplasmic reticulum 0.4515652450309861 1.4110958242038545 0.1582163611276992 0.9971370330490976 0.6635207837682652 202 O96005,P11047,P37268,O95197,Q6UW68,Q9P035,Q8IV08,Q8WUJ1,Q96CN7,O43852,P51648,Q5BJF2,O43731,Q14257,Q96S66,P35790,Q96G23,Q92791,Q9Y680,Q15800,P21964,Q9H0P0,P67809,O43169,P84157,Q16850,Q15041,Q96PC5,P13674,Q9NZ01,Q9H3G5,P49257,O95470,Q15125,O15027,Q9P2W9,Q16799,Q86XL3,Q9UBM7,Q03518,Q8N0U8,P53609,P43307,O15460,O95674 45 +Golgi apparatus 0.4292981975979846 1.1873185755974465 0.2351019837502845 0.9998897140531846 0.7691977960329479 186 P50897,Q8N4Q0,Q99523,Q8NCH0,P53365,Q7RTS9,P24390,Q8IZA0,Q93050,Q9NUJ3,Q9HD45,Q9NPR9,P80303,Q6NT16,P09601,Q9NWM8,O43752,Q8NBN3,Q8IXU6,Q6ZU35,Q02818,Q9HB40,P67812,Q5VW38,O75071,Q9HC07,O15027,O00461,O95456,Q96JB2 30 +Centriolar satellite 0.4186738368051996 1.0996570495779354 0.2714815750704522 0.9999789632638972 0.7691977960329479 33 Q9P260,Q9Y4W2,Q9UBK9,Q03518,Q86UY6,O43169 6 +Intermediate filaments 0.3800939954248255 0.806159440095967 0.4201509221108428 0.9999999910317232 0.8515469546636512 34 Q9NRW3,Q86YN1,O75718,P07196,Q96K76,Q3SXM5,P08670,Q16352 8 +Focal adhesion sites 0.363122297512865 0.6160485128256723 0.5378625019331627 0.9999999999959984 1.0 28 P08183,Q9UHB6,P11233,Q9Y487,Q969Q5,O60888,P36404 7 +Mitochondria 0.3278103872933106 0.4866912670408437 0.6264771348708362 0.9999999999999972 1.0 412 Q8N183,Q16740,Q9NX40,Q96ER9,Q9NS69,Q96AY3,P48735,Q9NQ50,Q7Z7H8,Q70HW3,P42574,Q99595,Q9BUR5,P00374,Q8TC07,O43772,Q9NUJ1,Q69YU5,Q8N4Q1,Q99797,P00367,P82912,P45880,Q96NB2,Q9H2D1,Q8IUX1,Q6NUK1,Q15386,P57105,P23786,Q9H7Z7,Q8N4H5,Q13084,Q9NR28,Q96CX2,Q5VT66,O95831,O75964,Q3SXM5,Q14168,Q5JRX3,Q96A26,Q9NVH6,Q8TAE8,P28070,P53701,Q9Y2R0,Q16836,Q96CU9,Q5T653,O14949,Q6DKK2,P51530,Q9NQE9,Q15070,P13674,Q9NYY8,Q9UDX5,O60313,O75306,O14925,Q15120,O95140,Q9NSE4,P12235,Q9NPL8,P34897,Q8NI60,P82675,Q9BYT8,Q9NQZ5,Q5XKP0,Q8N983,Q6P4A7,Q9H3K2,Q86Y39,Q9Y6C9,Q04837,Q9UBX3,Q9Y2S7,O75438,O95168,Q8WWC4,Q9NRF8,Q68CZ6,O75648,Q7LGA3,Q8N2F6,Q9BXK5,Q9Y6M9,Q9NX63,Q96TA2,P52789,P42126,Q9Y512,Q7KZN9,P82933,P30048 98 +Kinetochore 0.5891193267207764 0.3771236114615512 0.7060817450569306 1.0 1.0 2 Q9BZD4 1 +Cytoplasmic bodies 0.3345635706144275 0.3377682712263162 0.7355378219614295 1.0 1.0 20 Q9Y5A9,P06730 2 +Lipid droplets 0.3486861659359377 0.1916197915725487 0.8480400383631925 1.0 1.0 9 Q01105 1 +Peroxisomes 0.3233872797257998 0.1788874935950902 0.8580260430504831 1.0 1.0 14 Q9BY49,Q15067 2 +Cell Junctions 0.2702148197382023 0.0271410473103093 0.9783472357889388 1.0 1.0 49 P43490 1 diff --git a/protein_atlas_subcellular_location_all/selections.json b/protein_atlas_subcellular_location_all/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..f915ef61e72958f6dc515f08f2825117e1021e5f --- /dev/null +++ b/protein_atlas_subcellular_location_all/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin filaments", "Aggresome", "Cell Junctions", "Centriolar satellite", "Centrosome", "Cytokinetic bridge", "Cytoplasmic bodies", "Cytosol", "Endoplasmic reticulum", "Endosomes", "Focal adhesion sites", "Golgi apparatus", "Intermediate filaments", "Kinetochore", "Lipid droplets", "Lysosomes", "Microtubule ends", "Microtubules", "Midbody", "Midbody ring", "Mitochondria", "Mitotic chromosome", "Mitotic spindle", "Nuclear bodies", "Nuclear membrane", "Nuclear speckles", "Nucleoli", "Nucleoli fibrillar center", "Nucleoli rim", "Nucleoplasm", "Peroxisomes", "Plasma membrane", "Rods & Rings", "Vesicles"], "available_proteins": ["AAAS", "AACS", "AAGAB", "AAK1", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASS", "AATF", "ABCB1", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD11", "ABHD14B", "ABHD6", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACP1", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR6", "ADA", "ADAM17", "ADAR", "ADD1", "ADD3", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKT1", "AKT1S1", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG13", "ALG5", "ALKBH1", "ALKBH5", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP3B1", "AP3D1", "APC", "APEH", "APEX1", "API5", "APMAP", "APOBEC3C", "APOO", "APPL1", "APRT", "AQR", "ARCN1", "ARF6", "ARFGAP1", "ARFGAP3", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGAP35", "ARHGAP5", "ARHGDIA", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL6IP5", "ARMC1", "ARMC10", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARVCF", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATE1", "ATF7IP", "ATG3", "ATG4B", "ATG9A", "ATIC", "ATL2", "ATL3", "ATP13A1", "ATP1B3", "ATP2B1", "ATP5A1", "ATP5B", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6V0A1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATRX", "ATXN10", "ATXN2", "ATXN2L", "AUP1", "B4GALT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAZ1B", "BCAP31", "BCAS2", "BCAT2", "BCCIP", "BCL2L12", "BCL2L13", "BCLAF1", "BCOR", "BDH2", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOD1L1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAP", "BRAT1", "BRCA1", "BRD2", "BRD4", "BRI3BP", "BRIX1", "BROX", "BSG", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C12orf73", "C14orf2", "C15orf39", "C19orf25", "C19orf70", "C1QBP", "C1orf123", "C1orf35", "C20orf27", "C2CD5", "C2orf49", "C5orf15", "C5orf51", "CAB39", "CACTIN", "CACUL1", "CACYBP", "CAD", "CADM1", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAP2", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CASP2", "CASP3", "CAST", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC124", "CCDC138", "CCDC22", "CCDC43", "CCDC47", "CCDC51", "CCDC6", "CCDC86", "CCDC93", "CCDC94", "CCDC97", "CCNA2", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC25C", "CDC27", "CDC37", "CDC42", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP3", "CDK6", "CDKN2AIP", "CDR2L", "CDS2", "CDV3", "CDX2", "CEBPZ", "CECR2", "CELF1", "CENPB", "CENPE", "CENPI", "CENPU", "CENPV", "CEP170", "CEP250", "CEP55", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHCHD4", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK1", "CHEK2", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP5", "CHMP7", "CHORDC1", "CHP1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CIZ1", "CKAP2", "CKAP5", "CKB", "CLASP2", "CLCC1", "CLCN3", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN6", "CLNS1A", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTA", "CLTC", "CLU", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNOT1", "CNOT11", "CNOT3", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COG2", "COG3", "COG7", "COIL", "COLEC12", "COLGALT1", "COMMD1", "COMMD10", "COMMD7", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COQ8A", "CORO1B", "COTL1", "COX15", "COX4I1", "COX5B", "COX6C", "COX7A2L", "CPD", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CTTNBP2NL", "CUL1", "CUL2", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC22", "CWF19L1", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF7", "DCAF8", "DCAKD", "DCP1A", "DCP1B", "DCP2", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENND4C", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR7", "DHFR", "DHODH", "DHPS", "DHRS1", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC11", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPP3", "DPP9", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DTL", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFL1", "EFTUD2", "EGFR", "EHBP1", "EHD1", "EHD4", "EHMT2", "EIF2A", "EIF2AK2", "EIF2AK4", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELOA", "ELOC", "ELP1", "ELP2", "ELP4", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENSA", "EPB41", "EPB41L2", "EPB41L5", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERP29", "ESD", "ESF1", "ESS2", "ESYT1", "ESYT2", "ETFA", "ETFB", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC6B", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FABP5", "FAF1", "FAF2", "FAH", "FAHD1", "FAM114A1", "FAM114A2", "FAM160A2", "FAM162A", "FAM177A1", "FAM208A", "FAM49B", "FAM50A", "FAM83D", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD2", "FBL", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNBP4", "FNDC3A", "FNTA", "FNTB", "FOXRED1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLM", "GCN1", "GDAP1", "GDAP2", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GEMIN8", "GET4", "GFM1", "GFPT1", "GGA1", "GGT7", "GHITM", "GID4", "GID8", "GIGYF2", "GINS3", "GINS4", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNE", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM1", "GOLPH3", "GOLPH3L", "GOLT1B", "GOPC", "GORASP2", "GOT1", "GPAM", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR108", "GPR89B", "GPS1", "GPSM1", "GPT2", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSDME", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP3", "GTPBP4", "GTSE1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS1", "HAUS2", "HAUS3", "HAUS6", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HELLS", "HERC4", "HEXA", "HEXIM1", "HGH1", "HGS", "HIBCH", "HINT2", "HINT3", "HIP1", "HIRIP3", "HIST1H1C", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCS1", "HMGN1", "HMGN2", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOXD13", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B11", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA6", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPH1", "HTATSF1", "HTT", "HUWE1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IER3IP1", "IFIT5", "IFNGR1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "IKBKB", "IKBKG", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS11", "INTS12", "INTS13", "INTS14", "INTS3", "INTS7", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRGQ", "ISCU", "ISG20L2", "ISOC1", "ISOC2", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITSN2", "IVD", "IWS1", "JAGN1", "JMJD6", "JPT2", "JUP", "KARS", "KAT7", "KCTD12", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1211", "KIAA1468", "KIAA2013", "KIF11", "KIF14", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "L2HGDH", "LACTB", "LAMC1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCMT1", "LDHA", "LDHB", "LDLRAP1", "LEMD2", "LEMD3", "LETM1", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LMAN1", "LMF2", "LMNA", "LMNB1", "LMNB2", "LONP1", "LPCAT1", "LRBA", "LRCH2", "LRP1", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRWD1", "LSM12", "LSM14A", "LSM14B", "LSM2", "LSM6", "LTA4H", "LTN1", "LTV1", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYPLAL1", "LZIC", "LZTFL1", "LZTS2", "MACF1", "MAD1L1", "MAGED1", "MAGED2", "MAIP1", "MAK16", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K3", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARK2", "MARS", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MEAF6", "MECP2", "MED1", "MED14", "MED16", "MED21", "MED23", "MED4", "MEPCE", "METAP1", "METAP2", "METTL1", "METTL13", "METTL16", "MFAP1", "MFF", "MFN1", "MFN2", "MFSD10", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MICALL1", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MIPEP", "MKI67", "MKLN1", "MKRN2", "MMAB", "MMS19", "MOGS", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP7", "MPRIP", "MPST", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL19", "MRPL2", "MRPL21", "MRPL22", "MRPL23", "MRPL28", "MRPL37", "MRPL39", "MRPL40", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL50", "MRPL58", "MRPL9", "MRPS10", "MRPS11", "MRPS15", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH2", "MTDH", "MTERF3", "MTFP1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR2", "MTOR", "MTPAP", "MTR", "MTSS1L", "MTX1", "MTX2", "MTX3", "MUT", "MVK", "MXRA7", "MYBBP1A", "MYCBP", "MYCBP2", "MYG1", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA16", "NAA35", "NAA40", "NAA50", "NACC1", "NADK2", "NAE1", "NAGK", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCDN", "NCKAP1", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "NDC1", "NDC80", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF4", "NDUFB1", "NDUFB11", "NDUFB4", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEFL", "NEFM", "NELFA", "NELFCD", "NELFE", "NEMF", "NES", "NFATC2IP", "NFKB1", "NFS1", "NFU1", "NHLRC2", "NIFK", "NIP7", "NIPBL", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NMD3", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NRDE2", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSUN2", "NSUN5", "NSUN6", "NT5C3A", "NT5DC1", "NTMT1", "NTPCR", "NUB1", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP188", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NUPL2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PATL1", "PAXIP1", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNP", "PCNT", "PDAP1", "PDCD11", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXDC1", "PDXK", "PDZD8", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN1", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PGAM1", "PGAM5", "PGD", "PGGT1B", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF2", "PHF3", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PI4KB", "PIBF1", "PICALM", "PIGL", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2B", "PIR", "PISD", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLCB3", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLOD1", "PLOD2", "PLPBP", "PLRG1", "PLS3", "PMPCA", "PMPCB", "PMS1", "PNISR", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPO", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "POP1", "POR", "PPA1", "PPA2", "PPAT", "PPFIA1", "PPHLN1", "PPIB", "PPID", "PPIE", "PPIF", "PPIL1", "PPIL3", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PRIM2", "PRKAA1", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2B", "PRKCD", "PRKCSH", "PRKDC", "PRMT1", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF39", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA4", "PSMA5", "PSMA6", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR2", "PTPA", "PTPN1", "PTPN11", "PTPN23", "PTPN9", "PTPRF", "PTRH2", "PTRHD1", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PWP1", "PWP2", "PYCR2", "PYGB", "PYGL", "PYM1", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB11B", "RAB13", "RAB14", "RAB1A", "RAB1B", "RAB24", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB9A", "RABEP1", "RABEPK", "RABGAP1", "RABGGTB", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RANGRF", "RAP1GDS1", "RAPGEF2", "RAPGEF6", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM47", "RBM5", "RBM8A", "RBMX", "RBPMS", "RCC1", "RCL1", "RCN1", "RCN2", "RDH13", "RDH14", "RDX", "RECQL", "RECQL4", "RECQL5", "REEP4", "REEP5", "REPS1", "RER1", "RETREG3", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHOA", "RHOT2", "RIC8A", "RIF1", "RINT1", "RIOX1", "RIOX2", "RIPK1", "RMDN1", "RMND5A", "RNASEH2A", "RNASEH2B", "RNF14", "RNF20", "RNF219", "RNF220", "RNF40", "RNPEP", "RNPS1", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL32", "RPL34", "RPL35", "RPL36", "RPL36A", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPSA", "RPTOR", "RPUSD2", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCA", "RTCB", "RTF1", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SAAL1", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SBNO1", "SCAF1", "SCAF11", "SCAF4", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCML2", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC23A", "SEC23IP", "SEC24A", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD7", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL", "SH3BGRL2", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIN3A", "SIRT1", "SKA1", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC30A7", "SLC35B2", "SLC35F2", "SLC38A2", "SLC3A2", "SLC4A1AP", "SLC6A15", "SLC9A3R1", "SLFN11", "SLIRP", "SLK", "SLTM", "SLU7", "SMAP1", "SMAP2", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC6", "SMCHD1", "SMG8", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SNAP23", "SNAP29", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD2", "SNRPD3", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC24", "SPC25", "SPCS2", "SPDL1", "SPECC1", "SPECC1L", "SPEN", "SPHK2", "SPNS1", "SPPL2A", "SPR", "SPRYD4", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SQLE", "SQSTM1", "SRBD1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRPK1", "SRPK2", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRN", "STT3B", "STUB1", "STX12", "STX18", "STX4", "STX6", "STX7", "STX8", "STXBP2", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE1", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACC3", "TACO1", "TADA3", "TAF15", "TAGLN2", "TALDO1", "TAMM41", "TANGO6", "TAP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D13", "TBC1D15", "TBC1D2B", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCA", "TBCB", "TBCC", "TBK1", "TBL1XR1", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TCP11L1", "TDRD7", "TDRKH", "TECR", "TELO2", "TERF2", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFAP4", "TFCP2", "TFG", "TFIP11", "TFRC", "TGS1", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM17A", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM9", "TIMMDC1", "TJP1", "TJP2", "TKFC", "TKT", "TLN1", "TM9SF3", "TMA16", "TMA7", "TMCO1", "TMED10", "TMED2", "TMEM109", "TMEM11", "TMEM126A", "TMEM126B", "TMEM165", "TMEM192", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM245", "TMEM63A", "TMEM87A", "TMEM97", "TMF1", "TMLHE", "TMOD3", "TMX1", "TMX2", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOM1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1AIP1", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIO", "TRIP12", "TRIP13", "TRIR", "TRMT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMU", "TROVE2", "TRUB1", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPYL1", "TSR1", "TSR2", "TTC1", "TTC19", "TTC27", "TTC28", "TTC37", "TTC38", "TTC4", "TTF2", "TTI1", "TTK", "TTLL12", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUFM", "TWF1", "TWF2", "TWISTNB", "TXLNA", "TXLNG", "TXN2", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAP2", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE2T", "UBE3A", "UBE3C", "UBE4A", "UBLCP1", "UBP1", "UBQLN1", "UBQLN2", "UBQLN4", "UBR1", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UFSP2", "UGDH", "UGGT1", "UGP2", "UHRF1", "UHRF1BP1", "UMPS", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCC2", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "UROD", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP15", "USP24", "USP28", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "UXT", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VBP1", "VCL", "VCP", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS35", "VPS37C", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK2", "VTA1", "VTI1B", "WAPL", "WARS", "WARS2", "WASHC3", "WASHC5", "WASL", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR36", "WDR4", "WDR41", "WDR45B", "WDR46", "WDR48", "WDR5", "WDR6", "WDR61", "WDR70", "WDR77", "WDR82", "WIPI2", "WIZ", "WNK1", "WNK2", "WRAP53", "WTAP", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YAP1", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YEATS4", "YIF1A", "YIPF4", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF2", "YWHAB", "YWHAE", "YWHAG", "YWHAQ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZFR", "ZFYVE16", "ZMYM2", "ZMYM4", "ZMYND8", "ZNF24", "ZNF281", "ZNF318", "ZNF326", "ZNF512B", "ZNF622", "ZNF638", "ZPR1", "ZRANB2", "ZSWIM8", "ZW10", "ZYX"], "leading_proteins": ["ABCB1", "ABHD10", "ACOX1", "AIFM1", "ALDH3A2", "ANKLE2", "APOBEC3C", "APOO", "ARFIP2", "ARL2", "ARL6IP1", "ARMC10", "ATP5L", "ATP6V0A1", "ATP6V0A2", "BCL2L13", "C12orf73", "C19orf70", "CALU", "CASP3", "CCDC51", "CDS2", "CERS2", "CHCHD3", "CHCHD4", "CHKA", "CHST14", "CLCC1", "CLPP", "CLPTM1", "COA3", "COG3", "COMT", "COQ8A", "COX15", "CPT2", "CPVL", "CRTAP", "CTPS2", "CUTA", "CYB5B", "CYB5D2", "CYP51A1", "DHCR7", "DHFR", "DIABLO", "DNA2", "DOLPP1", "DYM", "EBP", "ECI1", "EFCAB14", "EIF4E", "FAM162A", "FASTKD2", "FDFT1", "FKBP10", "FKBP14", "FKBP7", "FOXRED1", "GADD45GIP1", "GHITM", "GLUD1", "GOLIM4", "GPR107", "GPR108", "HACD3", "HADH", "HAUS3", "HCCS", "HINT3", "HK2", "HMOX1", "HS2ST1", "HSDL1", "IARS2", "IDH2", "INA", "ISOC1", "KCTD12", "KDELR1", "KDELR3", "KIAA0319L", "KIAA1211", "KIAA1468", "LAMC1", "LAS1L", "LIMA1", "LMAN1", "MAIP1", "MARC1", "MFN2", "MIA2", "MIPEP", "MPP2", "MRPL10", "MRPL2", "MRPL28", "MRPL40", "MRPL43", "MRPS11", "MRPS5", "MRPS9", "MSMO1", "MTCH2", "MTFP1", "MXRA7", "NAA40", "NAMPT", "NDUFA11", "NDUFAF2", "NDUFB1", "NDUFB4", "NDUFB9", "NDUFS2", "NEFL", "NLN", "NT5C3A", "NUCB1", "NUCB2", "NUF2", "OCIAD1", "OPA1", "OXA1L", "P3H4", "P4HA1", "P4HA2", "PDK3", "PECR", "PGGT1B", "PITRM1", "PLD3", "POLDIP2", "PPT1", "PRDX3", "PSMB4", "PSMG1", "PTGES2", "RAB24", "RALA", "RCN2", "RTN1", "RTN3", "SAMM50", "SCPEP1", "SEC11A", "SEC16A", "SET", "SFXN2", "SFXN4", "SGPL1", "SHMT2", "SLC18B1", "SLC25A10", "SLC25A20", "SLC25A24", "SLC25A26", "SLC25A32", "SLC25A4", "SLC35F2", "SORT1", "SSBP1", "SSR1", "STARD7", "STX18", "STX6", "SYNJ2BP", "TAP1", "TBC1D15", "TCP11L1", "TECR", "TIMM17A", "TIMM23", "TIMMDC1", "TM9SF3", "TMEM126B", "TMEM165", "TMEM205", "TMEM87A", "TMEM97", "TMLHE", "TOMM22", "TOMM5", "TRMU", "TTC19", "UBE3C", "UQCRQ", "USP47", "UXT", "VDAC2", "VIM", "VKORC1L1", "YBX1", "YME1L1", "YTHDF2", "ZADH2"]} \ No newline at end of file