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interpro_active_site/advanced/idx2term.json

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+{}

interpro_active_site/basic/idx2term.json

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+{}

interpro_active_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:a16ffb7b2b7c3da590837640155417aaac175ea608433c4425cda7ba0ef15725
+size 81971

interpro_active_site/df_merge.tsv

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+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_active_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3329,
+    "annotations_size": 57,
+    "title": "Average number of proteins per term",
+    "value": 2.8421052631578947
+}

interpro_active_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C343/C343_val_log2fc"}

interpro_active_site/result.tsv

@@ -0,0 +1,4 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Histidine acid phosphatase active site [IPR033379]	0.9347760745416284	2.1278141149609815	0.0333524986074909	0.8553616148506122	0.095054621031349	2	Q9NPH0	1
+Ribonucleotide reductase small subunit, acitve site [IPR030475]	0.8722572888488056	1.858531071977778	0.0630936351483559	0.9756396910594516	0.1518694408110385	2	Q7LG56	1
+Serine carboxypeptidase, serine active site [IPR018202]	0.8638003607937368	1.8229952395733977	0.0683041118934371	0.982273287884287	0.1518694408110385	3	Q9HB40,P10619	2

interpro_active_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase,  active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]"], "available_proteins": ["AAK1", "ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT1", "APEH", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "BLMH", "BUB1", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CASP2", "CASP3", "CDC42BPB", "CDK1", "CDK11B", "CDK4", "CDK5", "CDK6", "CHEK1", "CHEK2", "CHUK", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSB", "CTSC", "DLD", "DNMT1", "DUSP3", "EGFR", "EIF2AK2", "EIF2AK4", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSK3A", "GSK3B", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "IGF1R", "IKBKB", "LDHA", "LDHB", "LONP1", "MAP2K1", "MAP2K3", "MAPK1", "MAPK3", "MARK1", "MARK2", "MDH1", "MDH2", "MTMR2", "NEK9", "NME1", "NME2", "NME3", "OXCT1", "PAK1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKN1", "PKN2", "PLK1", "PREP", "PRKAA1", "PRKAA2", "PRKACA", "PRKCD", "PRPF4B", "PTK7", "PTPN1", "PTPN11", "PTPN23", "PTPN9", "PTPRF", "RIPK1", "RNASET2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "RRM2B", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TPI1", "TPP2", "TRIO", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UBE2T", "UMPS", "VRK1", "VRK2", "WNK1", "WNK2"], "leading_proteins": ["ACP6", "CTSA", "RRM2B", "SCPEP1"]}

interpro_binding_site/advanced/idx2term.json

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+{"0": "EF-Hand 1, calcium-binding site [IPR018247]"}

interpro_binding_site/basic/idx2term.json

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+{"0": "EF-Hand 1, calcium-binding site [IPR018247]"}

interpro_binding_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:3d994e57b823a161134f340b35a23dc10e6a6738e0cd90d656b30d176c566485
+size 78915

interpro_binding_site/df_merge.tsv

@@ -0,0 +1,2 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+EF-Hand 1, calcium-binding site [IPR018247]	10	40	2.238726227546824	0.0251737349194831	10.019417475728156	36.70631067961165	0.9532938980945532	0.3894555773109194	3.76037227687173	3.057484685571999	1.1082350706804749	0.3408841825650379	0.0081647928718778	0.0551599902794207	0.0413282647695778	0.0424479309650379	0.0014756922477904

interpro_binding_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3329,
+    "annotations_size": 31,
+    "title": "Average number of proteins per term",
+    "value": 4.903225806451613
+}

interpro_binding_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C343/C343_val_log2fc"}

interpro_binding_site/result.tsv

@@ -0,0 +1,4 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+EF-Hand 1, calcium-binding site [IPR018247]	0.4958123188699386	2.238726227546824	0.0251737349194831	0.5463260084688515	0.0772161517285309	40	Q6NUK1,Q14257,P80303,P41208,O43852,Q9Y680,Q96AY3,Q9NWM8,O95202,Q02818	10
+Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]	0.6615569582206192	0.935720032618983	0.3494173536192351	0.9999983692900652	0.4166129985460111	2	P34897	1
+Peptidase M16, zinc-binding site [IPR001431]	0.4220928418041678	0.2032472485473326	0.838941784443999	1.0	0.8669065105921323	5	Q10713,P22695	2

interpro_binding_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT1", "APEX1", "APOBEC3C", "BPNT1", "BUB1", "CALM3", "CALU", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CAPNS1", "CDC42BPB", "CDK1", "CDK4", "CDK5", "CDK6", "CETN2", "CHEK1", "CHUK", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DCTD", "DLAT", "DLST", "DST", "EGFR", "EHD1", "EHD4", "EIF2AK2", "EIF2AK4", "EPS15", "EPS15L1", "FKBP10", "FKBP14", "FKBP7", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "IGF1R", "ILKAP", "IMPA1", "IQGAP1", "IQGAP2", "ITSN2", "LETM1", "MACF1", "MAP2K1", "MAP2K3", "MAPK1", "MAPK14", "MAPK3", "MARK1", "MARK2", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXCT1", "OXSR1", "PA2G4", "PAK1", "PAK2", "PAK4", "PC", "PCCA", "PDCD6", "PEF1", "PGD", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1G", "PRKAA1", "PRKAA2", "PRKACA", "PRKCD", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "STK26", "STK4", "TBK1", "TKT", "TTK", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "UQCRC2", "VRK1"], "leading_proteins": ["CALU", "CETN2", "FKBP10", "FKBP14", "FKBP7", "LETM1", "NUCB1", "NUCB2", "PMPCA", "RCN2", "SHMT2", "SLC25A24", "UQCRC2"]}

interpro_conserved_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_conserved_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Intermediate filament protein, conserved site [IPR018039]"}

interpro_conserved_site/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:b25ceeccd7b1ee0a6e2e30ab3748a1f81c6598337fccc80733dee40e366ab11e
+size 113579

interpro_conserved_site/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_conserved_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3329,
+    "annotations_size": 275,
+    "title": "Average number of proteins per term",
+    "value": 2.7854545454545456
+}

interpro_conserved_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C343/C343_val_log2fc"}

interpro_conserved_site/result.tsv

@@ -0,0 +1,31 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Haem oxygenase conserved site [IPR018207]	0.977457168620378	2.3084626628913947	0.0209734171967319	0.9970590806605022	0.0730087307481175	2	P30519	1
+Tetraspanin, conserved site [IPR018503]	0.978953698135898	2.2814108608429544	0.0225241459599589	0.9980982191145606	0.077426751737359	3	O43657,Q9H1Z9	2
+Glycoside hydrolase, family 29, conserved site [IPR018526]	0.9182446648632344	2.057121764319554	0.0396745146609558	0.9999853757040736	0.116069058848541	2	P04066	1
+Intermediate filament protein, conserved site [IPR018039]	0.714468092176739	1.9595751755438764	0.0500454652579362	0.999999261627404	0.1336165334556551	8	P07197,Q03252,P07196,P08670,Q16352,P20700	6
+Syntaxin/epimorphin, conserved site [IPR006012]	0.7916647954661085	1.7127876725962283	0.0867516088320923	0.9999999999854804	0.201042324313724	5	O43752,Q86Y82,Q9P2W9	3
+Sterol reductase, conserved site [IPR018083]	0.8346859032161	1.694458618613852	0.0901781687370046	0.999999999994836	0.2049503834931924	2	Q14739	1
+Proteasome beta-type subunit, conserved site [IPR016050]	0.636959909922701	1.575276362597333	0.1151926675749386	0.9999999999999976	0.2357786377411554	8	P28072,P49721,P28074	3
+Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]	0.7841899609257581	1.472182741609738	0.1409715365780575	1.0	0.2619403551281474	2	Q07820	1
+Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]	0.7841899609257581	1.472182741609738	0.1409715365780575	1.0	0.2619403551281474	2	Q07820	1
+Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]	0.7841899609257581	1.472182741609738	0.1409715365780575	1.0	0.2619403551281474	2	Q07820	1
+14-3-3 protein, conserved site [IPR023409]	0.6750727763795957	1.37704473128965	0.1684984185803655	1.0	0.2951405420993663	6	P31946,Q04917,P62258,P63104	4
+Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]	0.6780883678990088	1.0066639789477732	0.3140962777399889	1.0	0.4535711245124001	2	P01889	1
+Thioredoxin, conserved site [IPR017937]	0.4738804541904488	0.9705346061007912	0.331780083974075	1.0	0.4585598319994043	13	Q96JJ7,Q9H1E5	2
+HMG box A DNA-binding domain, conserved site [IPR017967]	0.5628382441370965	0.597862080852575	0.5499319631638755	1.0	0.6662171359914791	3	O15347,P26583	2
+Guanylate kinase, conserved site [IPR020590]	0.52733903171797	0.5815215724302241	0.5608889834137782	1.0	0.6765108352578466	5	Q14168	1
+Clathrin adaptor complex, small chain [IPR000804]	0.5617673579801661	0.5342136795136224	0.5931937058552712	1.0	0.7061829831610372	2	P53680	1
+Homeobox, conserved site [IPR017970]	0.5452359483017778	0.4746491604559943	0.6350370601760873	1.0	0.7368573483055866	2	P35453	1
+RNA polymerase, beta subunit, conserved site [IPR007121]	0.5326119627291828	0.4310397829854893	0.666439443963686	1.0	0.7636285295417237	2	P30876	1
+ABC transporter-like, conserved site [IPR017871]	0.3724265578892255	0.3293748129494461	0.7418724030026049	1.0	0.8143856007384616	9	P08183	1
+Hexapeptide transferase, conserved site [IPR018357]	0.5001502855425439	0.3274706366320773	0.7433119483103776	1.0	0.8143856007384616	2	Q9Y5P6	1
+Dynein light chain, type 1/2, conserved site [IPR019763]	0.4842200180342726	0.2817103133398322	0.7781656457523201	1.0	0.8425021755192442	2	Q96FJ2	1
+Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]	0.4305291818209208	0.2291239059010537	0.8187726134238902	1.0	0.869353160971312	5	P48735,O75874	2
+3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]	0.4517583408476096	0.2000501403754304	0.84144136726346	1.0	0.8899860615286596	2	Q16836	1
+Macrophage migration inhibitory factor, conserved site [IPR019829]	0.4105801021941684	0.1203918896715084	0.9041727157779638	1.0	0.9364327241906718	2	P14174	1
+NUDIX hydrolase, conserved site [IPR020084]	0.3954887218045154	0.1016673350404177	0.9190207306225192	1.0	0.9430250034372868	4	P36639,Q8IU60,Q9UKK9	3
+DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]	0.3790201382626931	0.077388607977005	0.9383144031215598	1.0	0.9575894655145958	2	O15160	1
+Ribosomal protein S5, N-terminal, conserved site [IPR018192]	0.3769161406672652	0.0750452011334482	0.940178747959785	1.0	0.9575894655145958	2	P82675	1
+Ras GTPase-activating protein, conserved site [IPR023152]	0.3258190562067832	0.0352982459015733	0.9718419220284964	1.0	0.982560766756752	2	Q13576	1
+Calreticulin/calnexin, conserved site [IPR018124]	0.3333643270173001	0.0261550029681769	0.9791337060213268	1.0	0.9863068467247798	3	P27824	1
+Alpha-D-phosphohexomutase, conserved site [IPR016066]	0.3211064341551399	0.0156613044507106	0.9875045977834972	1.0	0.991108629162269	3	O95394,P36871	2

interpro_conserved_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Clusterin, conserved site [IPR033986]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific,  conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "Dihydroorotate dehydrogenase, conserved site [IPR001295]", "DnaJ domain, conserved site [IPR018253]", "Dpy-30 motif [IPR007858]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FHF complex subunit HOOK interacting protein, KELAA motif [IPR045668]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "GoLoco motif [IPR003109]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Helix-turn-helix motif [IPR000047]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Homeobox, conserved site [IPR017970]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Pseudouridine synthase, RluC/RluD, conserved site [IPR006224]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Pyridoxamine 5'-phosphate oxidase, conserved site [IPR019740]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Rel homology domain, conserved site [IPR030492]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P,  conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class II, conserved site [IPR002011]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]"], "available_proteins": ["AAAS", "AACS", "AAMP", "ABCB1", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK3", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP2S1", "AP3M1", "APEX1", "ARIH2", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "BAG6", "BAX", "BAZ1A", "BAZ1B", "BCAT2", "BCS1L", "BDH2", "BLM", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD2", "BRD4", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAP2", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDH2", "CDK5RAP1", "CDKAL1", "CDX2", "CECR2", "CENPE", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD4", "CLGN", "CLU", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1B", "CORO1C", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYP51A1", "DCAF7", "DCP2", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHODH", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DIS3L2", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC21", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DPY30", "DRG1", "DRG2", "DSC3", "DSG2", "DST", "DTL", "DTYMK", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "EIF4E2", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L5", "EPDR1", "EPN1", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FAM160A2", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FUCA1", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLO1", "GMPPA", "GMPPB", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GPSM1", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GTF3C2", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HOXD13", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA6", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IGF1R", "ILVBL", "IMPA1", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INTS12", "IQGAP1", "IQGAP2", "IVD", "KDM2A", "KDSR", "KIF11", "KIF14", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIFC1", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LDLR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRP1", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME2", "MGST2", "MID1", "MIF", "MKRN2", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPST", "MRC2", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "MVK", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFL", "NEFM", "NES", "NFKB1", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD1", "NSD2", "NSF", "NSUN6", "NUBPL", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF2", "PHF3", "PHF8", "PHGDH", "PHIP", "PI4KA", "PI4KB", "PIK3C2A", "PIK3C3", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PMS1", "PNP", "PNPLA6", "PNPO", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKAR2B", "PRKDC", "PRPF19", "PRPF4", "PRPS1", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RBBP7", "RCL1", "RDH13", "RDX", "RECQL5", "RIDA", "RNF14", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RPUSD2", "RRP8", "RRP9", "RSF1", "RSL24D1", "RTCA", "S100A10", "S100A11", "SART1", "SBDS", "SCAF11", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC27A4", "SLIT2", "SMARCA4", "SMS", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STOM", "STRN", "STX12", "STX18", "STX4", "STX6", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SYNE1", "SYNE2", "TAP1", "TBL1XR1", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLN1", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM21", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIP13", "TRMT11", "TSFM", "TSPAN10", "TSPAN3", "TSPAN6", "TTF2", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUFM", "TXN2", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBA5", "UHRF1", "USP10", "USP11", "USP14", "USP15", "USP24", "USP28", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WARS2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR48", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZMYND8"], "leading_proteins": ["ABCB1", "AP2S1", "CANX", "DCP2", "DYNLL2", "FUCA1", "GMPPB", "HADH", "HLA-B", "HMGB2", "HMGB3", "HMOX2", "HOXD13", "IDH1", "IDH2", "INA", "IQGAP2", "LBR", "LMNB1", "LMNB2", "MCL1", "MIF", "MPP2", "MRPS5", "NEFL", "NEFM", "NUDT1", "NUDT5", "PGM1", "PGM3", "POLR1C", "POLR2B", "PSMB2", "PSMB5", "PSMB6", "STX12", "STX18", "STX6", "TMX3", "TMX4", "TSPAN10", "TSPAN6", "VIM", "YWHAB", "YWHAE", "YWHAH", "YWHAZ"]}

interpro_domain/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "EF-hand domain [IPR002048]"}

interpro_domain/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "EF-hand domain [IPR002048]", "1": "Intermediate filament, rod domain [IPR039008]", "2": "Band 7 domain [IPR001107]", "3": "Target SNARE coiled-coil homology domain [IPR000727]", "4": "Thioredoxin domain [IPR013766]", "5": "Phox homology [IPR001683]", "6": "RNA recognition motif domain, eukaryote [IPR003954]"}

interpro_domain/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:e321c911f52ae2a77195931440b699bdc8fe7be3e0003a935ce5273443ae3ef8
+size 516954

interpro_domain/df_merge.tsv

@@ -0,0 +1,4 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+EF-hand domain [IPR002048]	15	49	2.477027605862629	0.0132481654590468	12.385922330097088	43.512135922330096	1.0171858714399242	0.3947118087831401	4.608360476919044	4.087317384177653	1.201458704248258	0.3652478399429377	0.0088224210867099	0.0832266786690803	0.0732279741082547	0.0343450359550879	9.272076262338654e-05
+P-type ATPase, haloacid dehalogenase domain [IPR044492]	3	5	2.060376147528066	0.0393625953639489	2.941747572815534	6.145631067961165	0.9567723497044874	0.2732808833570771	1.8358630293390923	1.459204245106796	1.2102525517005158	0.2943240638910574	0.0034497378495243	1.0	1.0	0.0153906222854723	0.020271757680103
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	3	5	2.049699508453928	0.0403937630226711	2.813106796116505	6.104368932038835	1.6405397264547834	0.1100883340733615	1.2852875686886795	0.8042848477475721	1.100790504333474	0.1612592696854457	0.0002940175958919	0.0014481500629001	0.0057815105752346	0.000142755965642	0.000160552482799

interpro_domain/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3329,
+    "annotations_size": 2693,
+    "title": "Average number of proteins per term",
+    "value": 2.1927218715187524
+}

interpro_domain/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C343/C343_val_log2fc"}

interpro_domain/result.tsv

@@ -0,0 +1,194 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+EF-hand domain [IPR002048]	0.499951600999913	2.4770276058626295	0.0132481654590468	0.9999999999999998	0.049074703688051	49	Q6NUK1,Q14257,P80303,P41208,O43852,Q9UJS0,Q8NF37,Q9UBC2,Q9Y680,O75071,Q96AY3,Q9NWM8,O95202,Q02818,Q0IIM8	15
+GMP phosphodiesterase, delta subunit [IPR008015]	0.9678388938984072	2.2679950542567022	0.0233295081206432	1.0	0.0731389585202471	2	A6NIH7	1
+Reticulon [IPR003388]	0.9446616541353388	2.184129835581741	0.0289527088781682	1.0	0.0861543038772454	4	Q9NQC3,O95197,Q16799	3
+TRAM/LAG1/CLN8 homology domain [IPR006634]	0.938683498647424	2.1444657709531896	0.0319955852175608	1.0	0.0918861549873411	2	Q15629	1
+P-type ATPase, haloacid dehalogenase domain [IPR044492]	0.8750302092654997	2.060376147528066	0.0393625953639489	1.0	0.1060034693151144	5	P05023,P16615,Q9HD20	3
+Alpha-L-fucosidase, C-terminal [IPR031919]	0.9182446648632344	2.057121764319554	0.0396745146609558	1.0	0.1064177967947749	2	P04066	1
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	0.8724271072722242	2.0496995084539273	0.0403937630226711	1.0	0.1074905176087484	5	Q8WUJ1,O15173,O43169	3
+Cation-transporting P-type ATPase, N-terminal [IPR004014]	0.9158147925435932	2.03242081166355	0.0421110729734688	1.0	0.1098886817030538	3	P05023,P16615	2
+Cation-transporting P-type ATPase, C-terminal [IPR006068]	0.9158147925435932	2.03242081166355	0.0421110729734688	1.0	0.1098886817030538	3	P05023,P16615	2
+EXPERA domain [IPR033118]	0.9086263901412696	2.0158153696208103	0.0438192857812036	1.0	0.1126005120312799	2	Q15125	1
+SUN coiled coil domain 2 [IPR040994]	0.9077246768860836	2.011936417559073	0.0442266398742208	1.0	0.1127611143150259	2	O94901	1
+IMD/I-BAR domain [IPR013606]	0.9068229636308944	2.0080563685262014	0.0446373020312884	1.0	0.1134040135568489	2	Q765P7	1
+Choline/carnitine acyltransferase domain [IPR039551]	0.8972046889089288	1.9666018128344729	0.0492291343204349	1.0	0.1217392642102216	2	P50416	1
+Intermediate filament, rod domain [IPR039008]	0.714468092176739	1.9595751755438764	0.0500454652579362	1.0	0.1225203981269294	8	P07197,Q03252,P07196,P08670,Q16352,P20700	6
+Tim10-like [IPR004217]	0.8920625375826792	1.937243654817198	0.05271556623474	1.0	0.1275498830819002	3	Q9Y5J7,O60220	2
+ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]	0.8884881274421395	1.9289297263130152	0.0537395868866035	1.0	0.1289845877768478	2	Q9NVI7	1
+Tim44-like domain [IPR007379]	0.88307784791103	1.90549895033648	0.0567152437617695	1.0	0.1328123056090828	2	Q9BRJ2	1
+Armadillo repeat-containing domain [IPR006911]	0.8800721370604156	1.8924663394961383	0.0584288743837408	1.0	0.1359973714048524	2	Q8N2F6	1
+LEM domain [IPR003887]	0.7854830138895604	1.869358501900286	0.0615729539808656	1.0	0.1418442814974089	6	Q86XL3,P42167	2
+FAD linked oxidase, N-terminal [IPR006094]	0.8734595731890538	1.8637565483477572	0.0623559002428253	1.0	0.1429144164714286	2	Q15392	1
+FAD-binding domain, PCMH-type [IPR016166]	0.8734595731890538	1.8637565483477572	0.0623559002428253	1.0	0.1429144164714286	2	Q15392	1
+Guanylate-binding protein, N-terminal [IPR015894]	0.871956717763743	1.8572244417189576	0.0632792290055235	1.0	0.1442518832766124	2	Q8NHH9	1
+GB1/RHD3-type guanine nucleotide-binding (G) domain [IPR030386]	0.871956717763743	1.8572244417189576	0.0632792290055235	1.0	0.1442518832766124	2	Q8NHH9	1
+Guanylate-binding protein/Atlastin, C-terminal [IPR003191]	0.871956717763743	1.8572244417189576	0.0632792290055235	1.0	0.1442518832766124	2	Q8NHH9	1
+Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]	0.8716175586289737	1.8547002010047384	0.0636390500526213	1.0	0.1446244403305564	3	Q96RQ1,Q9Y282	2
+Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]	0.8716175586289737	1.8547002010047384	0.0636390500526213	1.0	0.1446244403305564	3	Q96RQ1,Q9Y282	2
+GPAT/DHAPAT, acyltransferase domain [IPR041728]	0.8701532912533816	1.8493824802301635	0.064402603413169	1.0	0.1461130673897761	2	Q9HCL2	1
+Glycerol-3-phosphate acyltransferase-like, C-terminal domain [IPR045520]	0.8701532912533816	1.8493824802301635	0.064402603413169	1.0	0.1461130673897761	2	Q9HCL2	1
+Band 7 domain [IPR001107]	0.6856368563685856	1.8184471113569576	0.0689958233439076	1.0	0.1536854857445354	8	O75955,Q9UJZ1,Q99623,Q14254,O94905,P35232,P27105	7
+FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]	0.6381560816357373	1.816182287570926	0.069342414207649	1.0	0.1542024124369933	10	Q9Y680,Q96AY3,Q9NWM8	3
+Phospholipid/glycerol acyltransferase [IPR002123]	0.8523308270676699	1.815043036256602	0.0695172960722092	1.0	0.1543364207110136	4	O15228,Q92604,Q9HCL2	3
+Peptidase M3A/M3B catalytic domain [IPR001567]	0.8583884546001102	1.8010006613968346	0.0717027757137462	1.0	0.1580160188192461	3	Q99797,P52888	2
+GOLD domain [IPR009038]	0.7647939539650817	1.7786867526008114	0.0752911322556537	1.0	0.1644436489574011	6	Q15363,Q9Y3B3,P49755,Q9Y3A6	4
+Fzo/mitofusin HR2 domain [IPR006884]	0.8437030357679616	1.7339632113559944	0.0829246108493226	1.0	0.1750125211733746	2	O95140	1
+Target SNARE coiled-coil homology domain [IPR000727]	0.6643695806736875	1.7129400383807278	0.0867235713723948	1.0	0.1791001362774994	8	Q9UEU0,O15400,O43752,Q86Y82,O95721	5
+Diacylglycerol kinase, catalytic domain [IPR001206]	0.8280733393447531	1.665444209262417	0.095824165547798	1.0	0.1914350725669288	2	Q9NRA0	1
+Legume-like lectin [IPR005052]	0.8247670574090731	1.650923944689909	0.0987541057994121	1.0	0.1954039727537228	2	P49257	1
+ERAP1-like C-terminal domain [IPR024571]	0.8171987228008663	1.6324884715709176	0.1025766251123245	1.0	0.1997388658188648	3	Q9UIQ6	1
+Intermediate filament head, DNA-binding domain [IPR006821]	0.8006015037593996	1.6030296814099028	0.1089281012352847	1.0	0.2080449479621431	4	P07197,P07196,P08670	3
+Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564]	0.7987657666454338	1.5565178996967877	0.1195849896275129	1.0	0.2211638016504754	3	Q13505	1
+Metaxin, glutathione S-transferase domain [IPR033468]	0.7987657666454338	1.5565178996967877	0.1195849896275129	1.0	0.2211638016504754	3	Q13505	1
+Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547]	0.802524797114518	1.5530490881660564	0.1204114077255233	1.0	0.2215965983067325	2	O15460	1
+Far upstream element-binding protein, C-terminal [IPR015096]	0.8007213706041449	1.5451008943867162	0.1223218606983631	1.0	0.2234822054685834	2	Q92945	1
+EB1, C-terminal [IPR004953]	0.7992185151788345	1.5384762473844569	0.1239322118384125	1.0	0.225202055655091	2	Q15555	1
+RBM3/CIRBP, RNA recognition motif [IPR034278]	0.79891794409378	1.5371511966741176	0.1242562882204429	1.0	0.2253446972142486	2	P98179	1
+Peptidase M28 [IPR007484]	0.7899203257670895	1.5199608188649556	0.1285208232973151	1.0	0.2308916458570178	3	Q7Z2K6	1
+Zinc finger, CHHC-type [IPR012996]	0.7859290438965687	1.503446423779394	0.1327239628670704	1.0	0.2357688865442089	3	P31943,P52597	2
+Immunoglobulin-like domain [IPR007110]	0.5564247090415797	1.4661063106066898	0.1426193267948134	1.0	0.246517231744822	13	Q9Y639,P35613,Q08722	3
+Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]	0.6401995380841485	1.4115190778728934	0.1580916143400761	1.0	0.2631277610740574	7	O60313,O95140	2
+Dynamin, N-terminal [IPR045063]	0.6401995380841485	1.4115190778728934	0.1580916143400761	1.0	0.2631277610740574	7	O60313,O95140	2
+AMPK, C-terminal adenylate sensor domain [IPR032270]	0.7700631199278655	1.40982049418334	0.1585926935552839	1.0	0.2636358788545553	2	Q13131	1
+SUN domain [IPR012919]	0.7629569784893385	1.4082075663062474	0.15906961645836	1.0	0.2642655626911558	3	O94901	1
+LEM-like domain [IPR013146]	0.7688608355875981	1.4045125021341924	0.1601662914335482	1.0	0.2654325063572587	2	P42167	1
+Syntaxin, N-terminal domain [IPR006011]	0.7603728202044429	1.3974776647876552	0.1622699785826022	1.0	0.2685882312986772	3	Q86Y82,O15400	2
+Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]	0.7628494138863826	1.377973914226198	0.168211342189779	1.0	0.2747077892765767	2	O60506	1
+14-3-3 domain [IPR023410]	0.6750727763795957	1.37704473128965	0.1684984185803655	1.0	0.2750098431738935	6	P31946,Q04917,P62258,P63104	4
+Zinc finger C2H2 AKAP95-type [IPR034736]	0.7453729767106503	1.3351534946513095	0.1818261140920904	1.0	0.2900815907879145	3	O43823	1
+Lamin tail domain [IPR001322]	0.744437763078768	1.3312659768911503	0.1831015090265453	1.0	0.2915750842615642	3	Q03252,P20700	2
+v-SNARE, coiled-coil homology domain [IPR042855]	0.7414311485267583	1.318767210402854	0.1872469494530049	1.0	0.2957254498312541	3	O75396,O15498	2
+Longin domain [IPR010908]	0.7414311485267583	1.318767210402854	0.1872469494530049	1.0	0.2957254498312541	3	O75396,O15498	2
+CS domain [IPR007052]	0.5496441208262006	1.303477818814501	0.1924116842463039	1.0	0.3005595395184604	9	Q9HB71	1
+Immunoglobulin subtype 2 [IPR003598]	0.5382155783173297	1.2400926524730516	0.2149411263248783	1.0	0.3254538248422804	9	P35613	1
+Immunoglobulin subtype [IPR003599]	0.5382155783173296	1.240092652473051	0.2149411263248786	1.0	0.3254538248422804	9	P35613	1
+Polyketide synthase, enoylreductase domain [IPR020843]	0.644311646790008	1.2369244769877792	0.2161151219602839	1.0	0.3260493128510054	6	Q8N4Q0,Q14914	2
+PDZ domain 6 [IPR041489]	0.716260895701816	1.1728271891705973	0.2408651124933647	1.0	0.3501550496462621	2	Q92614	1
+L27 domain [IPR004172]	0.6965413533834608	1.1693974680932002	0.2422435294745275	1.0	0.3512987748383967	4	O14936,Q14168,Q9NZW5	3
+L27 domain, C-terminal [IPR014775]	0.6965413533834608	1.1693974680932002	0.2422435294745275	1.0	0.3512987748383967	4	O14936,Q14168,Q9NZW5	3
+Importin-alpha, importin-beta-binding domain [IPR002652]	0.661734272576894	1.1528855069591557	0.2489573815218677	1.0	0.3552952985895017	5	P52292,O00629,P52294	3
+Pericentrin/AKAP-450 centrosomal targeting domain [IPR019528]	0.7042380522993644	1.1202172902636434	0.2626211776504026	1.0	0.3681618070861708	2	O95613	1
+Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]	0.6815714796152617	1.106842136454636	0.2683621868697137	1.0	0.3746497507724929	4	Q32P28,O15460	2
+CARG-binding factor, N-terminal [IPR012956]	0.6934174932371528	1.073063856931024	0.2832424660857713	1.0	0.3833888844494844	2	Q99729	1
+MHC class I-like antigen recognition-like [IPR011161]	0.678292242934442	1.0568604867267737	0.290575264063081	1.0	0.3895764011719622	3	P10321,P01889	2
+Immunoglobulin C1-set [IPR003597]	0.678292242934442	1.0568604867267737	0.290575264063081	1.0	0.3895764011719622	3	P10321,P01889	2
+MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]	0.678292242934442	1.0568604867267737	0.290575264063081	1.0	0.3895764011719622	3	P10321,P01889	2
+MHC class I, alpha chain, C-terminal [IPR010579]	0.678292242934442	1.0568604867267737	0.290575264063081	1.0	0.3895764011719622	3	P10321,P01889	2
+NOPS [IPR012975]	0.6746843054720382	1.041986622246453	0.2974178812881152	1.0	0.3967044845512106	3	Q15233,P23246	2
+CTP synthase, N-terminal [IPR017456]	0.681695220919748	1.0222396155009037	0.3066675051309402	1.0	0.4035296836935835	2	P17812	1
+CTP synthase GATase domain [IPR033828]	0.681695220919748	1.0222396155009037	0.3066675051309402	1.0	0.4035296836935835	2	P17812	1
+Aminopeptidase N-like , N-terminal domain [IPR045357]	0.6308101265160376	1.018545197022311	0.3084189332108216	1.0	0.4039565439582652	5	Q9UIQ6	1
+Peptidase M1, membrane alanine aminopeptidase [IPR014782]	0.6308101265160376	1.018545197022311	0.3084189332108216	1.0	0.4039565439582652	5	Q9UIQ6	1
+EF-hand, Ca insensitive [IPR014837]	0.6498908077891096	0.975019588833563	0.329550543258378	1.0	0.4202081500922406	4	P12814,O43707	2
+GYF domain [IPR003169]	0.6684700931770157	0.9652928796623296	0.3343981371666353	1.0	0.4247802751838438	2	O95400	1
+GINS subunit, domain A [IPR021151]	0.6678689510068928	0.9627156628663353	0.3356902342774324	1.0	0.4256185503338632	2	Q9BRX5	1
+Sorting nexin Vps5-like, C-terminal [IPR015404]	0.6451553658550918	0.9554201212176888	0.3393652826209008	1.0	0.4273554196233475	4	Q9Y5X3,O60749	2
+Pleckstrin homology domain 9 [IPR041681]	0.6648632401562986	0.9498455130331744	0.3421907560032486	1.0	0.4290976535385289	2	Q01082	1
+Pleckstrin homology domain, spectrin-type [IPR001605]	0.6648632401562986	0.9498455130331744	0.3421907560032486	1.0	0.4290976535385289	2	Q01082	1
+Serine hydroxymethyltransferase-like domain [IPR039429]	0.6615569582206192	0.935720032618983	0.3494173536192351	1.0	0.4350244731612607	2	P34897	1
+Fxr1, tudor domain [IPR041560]	0.6443174984966867	0.917631702184263	0.3588117148734469	1.0	0.4422333858829256	3	P51114,P51116	2
+Agenet-like domain [IPR008395]	0.6443174984966867	0.917631702184263	0.3588117148734469	1.0	0.4422333858829256	3	P51114,P51116	2
+Synaptic functional regulator FMRP, KH0 domain [IPR040472]	0.6443174984966867	0.917631702184263	0.3588117148734469	1.0	0.4422333858829256	3	P51114,P51116	2
+Fragile X-related 1 protein, C-terminal core [IPR022034]	0.6443174984966867	0.917631702184263	0.3588117148734469	1.0	0.4422333858829256	3	P51114,P51116	2
+Fragile X-related 1 protein, C-terminal region 1 [IPR032172]	0.6516381124135884	0.8935581359113121	0.3715583538574134	1.0	0.4519454481935036	2	P51116	1
+OCRE domain [IPR041591]	0.6513375413285125	0.892285835645639	0.3722397443629037	1.0	0.4525695853586003	2	P98175	1
+p21 activated kinase binding domain [IPR033923]	0.6349929220826147	0.8798320235530928	0.3789503138140782	1.0	0.4586576157758708	3	Q13177	1
+Importin-beta, N-terminal domain [IPR001494]	0.4587361370531082	0.8786575682723883	0.3795869718377782	1.0	0.4588095669475479	13	Q92973,Q8TEX9,O15397	3
+EF hand associated, type-2 [IPR013567]	0.6477306883077878	0.8770441957716479	0.3804626332714704	1.0	0.4589478754234829	2	Q8IXI1	1
+EF hand associated, type-1 [IPR013566]	0.6477306883077878	0.8770441957716479	0.3804626332714704	1.0	0.4589478754234829	2	Q8IXI1	1
+MIRO domain [IPR020860]	0.6477306883077878	0.8770441957716479	0.3804626332714704	1.0	0.4589478754234829	2	Q8IXI1	1
+GRAM domain [IPR004182]	0.6250843805055077	0.8727938784194826	0.3827754368554359	1.0	0.4602313744406279	4	Q969T9,Q0IIM8	2
+ABC transporter type 1, transmembrane domain [IPR011527]	0.5959729864533236	0.8682779415312438	0.3852421948294315	1.0	0.4617256785620836	5	P08183	1
+SCP2 sterol-binding domain [IPR003033]	0.6307163661044877	0.8625715038854532	0.3883731035249691	1.0	0.464632948819521	3	P51659	1
+Peptidase M16, N-terminal [IPR011765]	0.5221282478241102	0.8387593104842883	0.4016043882124367	1.0	0.4753936780026778	7	Q10713,P22695,Q5JRX3	3
+Peptidase M16, C-terminal [IPR007863]	0.5221282478241102	0.8387593104842883	0.4016043882124367	1.0	0.4753936780026778	7	Q10713,P22695,Q5JRX3	3
+Peptidase M41 [IPR000642]	0.6248872858431065	0.7817588700061032	0.4343562969668155	1.0	0.5061538328566138	2	Q9Y4W6	1
+DNA2/NAM7 helicase-like, C-terminal [IPR041679]	0.5926709916788486	0.7414720174262843	0.4584072923220319	1.0	0.5295970991948658	4	Q9HCE1	1
+Glutathione S-transferase, N-terminal [IPR004045]	0.4457096835154656	0.7226573632973451	0.4698904164220421	1.0	0.5382453812950061	9	Q8TB36,O15217,P78417	3
+Prolyl 4-hydroxylase, alpha subunit [IPR006620]	0.4942987584259979	0.7051074824613112	0.4807433504130085	1.0	0.548577051975522	7	Q32P28,P13674,O15460	3
+Glutamine amidotransferase type 2 domain [IPR017932]	0.5877895390330687	0.692742594726696	0.4884711031889688	1.0	0.5552776196234246	3	Q06203	1
+PABP, RNA recognition motif 2 [IPR045305]	0.5978358881875628	0.672345210524668	0.501363954109985	1.0	0.5664281170334258	2	P11940	1
+NUC153 [IPR012580]	0.5963330327622535	0.6663968428805371	0.5051574799382414	1.0	0.5696771748214758	2	Q9H501	1
+Glycosyltransferase 2-like [IPR001173]	0.5422414829992742	0.6421738181292417	0.5207603306455084	1.0	0.584891009274659	5	Q9Y673,Q10471,Q10472	3
+Zinc finger, RanBP2-type [IPR001876]	0.4310973143734057	0.6417472102503258	0.5210373305792451	1.0	0.584891009274659	9	P35637,P98175,Q92804	3
+Glycosyl hydrolase, family 13, catalytic domain [IPR006047]	0.5882176134655916	0.6345423415819005	0.5257269432327196	1.0	0.5894182590032114	2	P08195	1
+Major facilitator superfamily domain [IPR020846]	0.5650526612444707	0.632586920810144	0.5270034303683904	1.0	0.5906034758191706	4	Q14728,Q6NT16	2
+ARHGEF1-like, PH domain [IPR041020]	0.5852119026149736	0.6228632039206953	0.5333744200564294	1.0	0.5967500262617218	2	Q12802	1
+BAG domain [IPR003103]	0.5596001382411607	0.6115154423118546	0.5408583983259729	1.0	0.6038688502039159	4	O95429,Q9UL15	2
+Sterile alpha motif domain [IPR001660]	0.5309867629362024	0.596259640853248	0.5510017882989096	1.0	0.6131602544995717	5	Q5PRF9,Q9UQR0,Q9Y3Z3,Q9Y6Y8	4
+YTH domain [IPR007275]	0.5283939484469496	0.5857761927023937	0.5580259243489738	1.0	0.6204640025895072	5	Q9Y5A9,Q9BYJ9,Q9H6S0	3
+CBS domain [IPR000644]	0.5277690744491437	0.5832552361676177	0.5597214919787747	1.0	0.6220924382578789	5	Q8NE01,P51790	2
+Heat shock protein DnaJ, cysteine-rich domain [IPR001305]	0.5574648017895185	0.5779038451909464	0.5633290391142993	1.0	0.6258436890820165	3	Q96EY1	1
+Oxoglutarate/iron-dependent dioxygenase [IPR005123]	0.4433191510437485	0.5763609329252565	0.5643712448804523	1.0	0.6267429948301271	8	Q32P28,P13674,O15460	3
+Extended PHD (ePHD) domain [IPR034732]	0.561166215810043	0.532002249812369	0.5947244372860678	1.0	0.6563905367259757	2	Q8IWS0	1
+BRO1 domain [IPR004328]	0.5414912808177942	0.5197258894299486	0.6032546396708116	1.0	0.6647155256274532	3	Q9H3S7,Q8WUM4	2
+ALIX V-shaped domain [IPR025304]	0.5566576495341166	0.5155226369312899	0.6061878552823265	1.0	0.6676743943866279	2	Q8WUM4	1
+DnaJ domain [IPR001623]	0.3821870175649326	0.5149944395718653	0.6065569055859199	1.0	0.6678077460109904	17	Q96KC8	1
+Aminotransferase, class I/classII [IPR004839]	0.4827273850047338	0.5121986095496989	0.6085120161412112	1.0	0.6694154930831294	6	O15269	1
+Hotdog acyl-CoA thioesterase (ACOT)-type domain [IPR033120]	0.5503456567478214	0.4927752929480394	0.6221713701189189	1.0	0.6824877799308549	2	Q9Y305	1
+bMERB domain [IPR022735]	0.5467388037270842	0.4799529270851059	0.6312608653154974	1.0	0.6921765107062844	2	Q8N3F8	1
+Domain of unknown function DUF4217 [IPR025313]	0.5182590425681595	0.4386210041437571	0.6609361750747031	1.0	0.719733570350253	3	Q13206	1
+Man1/Src1, C-terminal [IPR018996]	0.5347159603246261	0.438187765597855	0.6612501766269412	1.0	0.7197844485272241	2	Q9Y2U8	1
+RNA polymerase, beta subunit, protrusion [IPR007644]	0.5326119627291828	0.4310397829854893	0.666439443963686	1.0	0.7225126499976677	2	P30876	1
+RNA polymerase Rpb2, domain 2 [IPR007642]	0.5326119627291828	0.4310397829854893	0.666439443963686	1.0	0.7225126499976677	2	P30876	1
+RNA polymerase Rpb2, domain 7 [IPR007641]	0.5326119627291828	0.4310397829854893	0.666439443963686	1.0	0.7225126499976677	2	P30876	1
+RNA polymerase Rpb2, domain 3 [IPR007645]	0.5326119627291828	0.4310397829854893	0.666439443963686	1.0	0.7225126499976677	2	P30876	1
+DNA-directed RNA polymerase, subunit 2, hybrid-binding domain [IPR007120]	0.5326119627291828	0.4310397829854893	0.666439443963686	1.0	0.7225126499976677	2	P30876	1
+FAST kinase-like protein, subdomain 2 [IPR013579]	0.5126277811184408	0.4196694237697763	0.6747269647723686	1.0	0.7289752243674847	3	Q9NYY8,Q969Z0	2
+FAST kinase leucine-rich [IPR010622]	0.5126277811184408	0.4196694237697763	0.6747269647723686	1.0	0.7289752243674847	3	Q9NYY8,Q969Z0	2
+RAP domain [IPR013584]	0.5126277811184408	0.4196694237697763	0.6747269647723686	1.0	0.7289752243674847	3	Q9NYY8,Q969Z0	2
+GAR domain [IPR003108]	0.5290051097084486	0.4189021392771161	0.6752876535525507	1.0	0.7289752243674847	2	Q9UPN3	1
+Class II aldolase/adducin N-terminal [IPR001303]	0.5241959723474701	0.4029518651361068	0.6869836354231817	1.0	0.7403148980370662	2	Q9UEY8	1
+MoaB/Mog domain [IPR001453]	0.5208896904117924	0.3921445328947093	0.6949514247469673	1.0	0.7471074598177976	2	Q8NFF5	1
+Proteasome activator PA28, N-terminal domain [IPR003185]	0.503607937462415	0.3899461927825299	0.6965763353812986	1.0	0.7482569091271787	3	Q06323,Q9UL46	2
+Proteasome activator PA28, C-terminal domain [IPR003186]	0.503607937462415	0.3899461927825299	0.6965763353812986	1.0	0.7482569091271787	3	Q06323,Q9UL46	2
+Nucleotidyl transferase domain [IPR005835]	0.5003006614551965	0.3792512100503909	0.7045013267748212	1.0	0.754963021490089	3	Q9Y5P6,Q9NR50	2
+CRIB domain [IPR000095]	0.4734001090815351	0.374230835803261	0.7082325843531716	1.0	0.7583579919137539	5	Q13177,Q9Y5S2	2
+STAG [IPR013721]	0.5136759843703158	0.3690272021638971	0.7121074491436437	1.0	0.7606923286568157	2	Q8N3U4	1
+Stromalin conservative domain [IPR020839]	0.5136759843703158	0.3690272021638971	0.7121074491436437	1.0	0.7606923286568157	2	Q8N3U4	1
+Fumarylacetoacetase-like, C-terminal [IPR011234]	0.5118725578599407	0.3633493269914071	0.7163439498994268	1.0	0.7646112790642713	2	P16930	1
+TOG domain [IPR034085]	0.4163544858919498	0.3505516699012398	0.7259247200271215	1.0	0.7736433372385483	7	Q8TEX9	1
+Thioredoxin domain [IPR013766]	0.3165644200858255	0.3458528019813408	0.7294533407056643	1.0	0.7764497417076498	26	Q6DKJ4,Q96JJ7,Q9H3N1,Q9Y320,Q9H1E5	5
+ABC transporter-like, ATP-binding domain [IPR003439]	0.3724265578892255	0.3293748129494461	0.7418724030026049	1.0	0.7871304875219209	9	P08183	1
+Dehydrogenase, E1 component [IPR001017]	0.4962428614367395	0.3159188453287719	0.7520641074221455	1.0	0.7936162387491528	2	Q02218	1
+Ubiquitin system component CUE [IPR003892]	0.469774436090229	0.2953583759667296	0.7677201268035061	1.0	0.8069751371904145	4	Q9H1I8,Q9H4L7,Q9Y679	3
+Phox homology [IPR001683]	0.3584475569820742	0.2905432266601156	0.7714006861303124	1.0	0.8098955351847685	13	Q9Y5X3,O60749,Q96L92,O95219,Q9UMY4	5
+Ribosomal protein L10e/L16 [IPR016180]	0.485121731289464	0.2842045122771377	0.7762536576908554	1.0	0.814355707113936	2	Q9NX20	1
+Zinc finger, ZZ-type [IPR000433]	0.4833183047790906	0.2792279019962683	0.7800699321696904	1.0	0.8170860860883178	2	P46939	1
+PB1 domain [IPR000270]	0.4833183047790752	0.2792279019962255	0.7800699321697233	1.0	0.8170860860883178	2	Q92734	1
+XPC-binding domain [IPR015360]	0.4733994589720551	0.2527106344468387	0.8004918294704348	1.0	0.8352283985911976	2	P54725	1
+RAD23A/RAD23B, UBA1 domain [IPR041811]	0.4733994589720551	0.2527106344468387	0.8004918294704348	1.0	0.8352283985911976	2	P54725	1
+Isopropylmalate dehydrogenase-like domain [IPR024084]	0.4305291818209208	0.2291239059010537	0.8187726134238902	1.0	0.8517291973684106	5	P48735,O75874	2
+Guanylate kinase-like domain [IPR008144]	0.3844394907360854	0.2213166899565999	0.824845855470512	1.0	0.8573175950529096	7	Q14168	1
+Guanylate kinase/L-type calcium channel beta subunit [IPR008145]	0.3844394907360854	0.2213166899565999	0.824845855470512	1.0	0.8573175950529096	7	Q14168	1
+Sorting nexin, N-terminal [IPR005329]	0.4604749023143998	0.2203859178022718	0.8255706117839354	1.0	0.8577398370116274	2	O60749	1
+3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108]	0.4517583408476096	0.2000501403754304	0.84144136726346	1.0	0.8718744140209687	2	Q16836	1
+3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176]	0.4517583408476096	0.2000501403754304	0.84144136726346	1.0	0.8718744140209687	2	Q16836	1
+Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778]	0.4323880989214771	0.1880875586476523	0.8508080138030973	1.0	0.8795493209872327	3	Q9BUJ2	1
+Vacuolar protein sorting-associated protein 13-like, N-terminal domain [IPR026854]	0.4442440637210673	0.1834848415251964	0.854417611579837	1.0	0.8826032328287307	2	Q6BDS2	1
+Ribosomal protein/NADH dehydrogenase domain [IPR007741]	0.4409377817853935	0.1764819218794563	0.8599153500238614	1.0	0.8869215004267555	2	Q8N983	1
+GCF, C-terminal [IPR022783]	0.4325217914036847	0.1594487690504496	0.8733153182062507	1.0	0.8996117830640722	2	P16383	1
+Chromo domain subgroup [IPR017984]	0.414311485267586	0.1476835112110442	0.8825925450799159	1.0	0.9075302496755302	3	Q13185,P45973	2
+Chromo shadow domain [IPR008251]	0.414311485267586	0.1476835112110442	0.8825925450799159	1.0	0.9075302496755302	3	Q13185,P45973	2
+Proteasome component (PCI) domain [IPR000717]	0.3209698783339501	0.1435083711274679	0.8858887004768943	1.0	0.9105718589252962	17	Q9BT78	1
+Glycogen synthase kinase 3, catalytic domain [IPR039192]	0.4238052299368732	0.1430091997946599	0.8862829154929686	1.0	0.9106062847714887	2	P49840	1
+Septin-type guanine nucleotide-binding (G) domain [IPR030379]	0.4008538604603797	0.1426096578175426	0.8865984696141269	1.0	0.9106062847714887	5	Q14141	1
+Kinesin-associated [IPR032405]	0.4108806732792317	0.1208750287402399	0.9037900213007484	1.0	0.9268494011282998	2	Q15058	1
+PTB/PI domain [IPR006020]	0.4030075187969963	0.1176642302097725	0.9063337099997556	1.0	0.9283973682119978	4	Q9UKG1,O60343,Q5SW96	3
+Isochorismatase-like [IPR000868]	0.4075743913435484	0.1156388234966764	0.9079387925938608	1.0	0.9296878967510522	2	Q96CN7	1
+RNA recognition motif domain, eukaryote [IPR003954]	0.3193142955974333	0.0981055263082436	0.9218484993387666	1.0	0.9407116364984078	14	Q14498,Q9UHX1,P38159,Q01085,Q14011	5
+Peptidase S9A, N-terminal domain [IPR023302]	0.3907424105801067	0.0916112904534238	0.9270068806915236	1.0	0.9446635259570078	2	Q4J6C6	1
+R3H domain [IPR001374]	0.37823211064342	0.0816437836311236	0.9349299831876936	1.0	0.9511773497259006	3	Q9H6S0,O95453	2
+DNA-directed RNA polymerase, RpoA/D/Rpb3-type [IPR011263]	0.3790201382626931	0.077388607977005	0.9383144031215598	1.0	0.9538998443210118	2	O15160	1
+DNA-directed RNA polymerase, insert domain [IPR011262]	0.3790201382626931	0.077388607977005	0.9383144031215598	1.0	0.9538998443210118	2	O15160	1
+Ribosomal protein S5, C-terminal [IPR005324]	0.3769161406672652	0.0750452011334482	0.940178747959785	1.0	0.9550740732763866	2	P82675	1
+Ribosomal protein S5, N-terminal [IPR013810]	0.3769161406672652	0.0750452011334482	0.940178747959785	1.0	0.9550740732763866	2	P82675	1
+MRH domain [IPR044865]	0.3662056524353586	0.0639665091360388	0.9489968940109136	1.0	0.9607701637486432	3	P20645,P11717	2
+Peptidase M16, middle/third domain [IPR032632]	0.3501653140967736	0.050408574465033	0.9597968036398709	1.0	0.9702450421179324	2	O43847	1
+HTH CenpB-type DNA-binding domain [IPR006600]	0.3384430417793804	0.0423562673520345	0.966214690636592	1.0	0.975634106443323	2	Q7Z3K3	1
+DDE superfamily endonuclease domain [IPR004875]	0.3384430417793804	0.0423562673520345	0.966214690636592	1.0	0.975634106443323	2	Q7Z3K3	1
+RasGAP protein, C-terminal [IPR000593]	0.3258190562067832	0.0352982459015733	0.9718419220284964	1.0	0.9791134665255296	2	Q13576	1
+Alpha-D-phosphohexomutase, alpha/beta/alpha domain III [IPR005846]	0.3210099188458062	0.0330073315056928	0.973668741132345	1.0	0.980220530792301	2	P36871	1
+Alpha-D-phosphohexomutase, alpha/beta/alpha domain II [IPR005845]	0.3210099188458062	0.0330073315056928	0.973668741132345	1.0	0.980220530792301	2	P36871	1
+Ras GTPase-activating domain [IPR001936]	0.3259170174383697	0.0195623845911005	0.9843924708347568	1.0	0.9906460851860984	3	Q13576,Q14C86	2
+Alpha-D-phosphohexomutase, alpha/beta/alpha domain I [IPR005844]	0.3211064341551399	0.0156613044507106	0.9875045977834972	1.0	0.9934067545128716	3	O95394,P36871	2

interpro_family/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Mitochondrial carrier protein [IPR002067]"}

interpro_family/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Mitochondrial carrier protein [IPR002067]", "1": "Short-chain dehydrogenase/reductase SDR [IPR002347]"}

interpro_family/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:86a70750c8f170acf3722380d4e81c9f5b6f896215aabda016b15eb1ca197423
+size 633477

interpro_family/df_merge.tsv

@@ -0,0 +1,3 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Mitochondrial carrier protein [IPR002067]	9	10	2.41883649511576	0.0155702371210346	5.686893203883495	11.07766990291262	0.8032246115450145	0.31892620527414	3.2338505495684404	1.5403272908315857	1.3918146051602212	0.3274613788058813	0.4477846407488154	1.0	1.0	0.3879443652654283	0.0144964406909979
+P-type ATPase [IPR001757]	3	5	2.060376147528066	0.0393625953639489	2.941747572815534	6.145631067961165	0.9567723497044874	0.2732808833570771	1.8358630293390923	1.459204245106796	1.2102525517005158	0.2943240638910574	0.0034497378495243	1.0	1.0	0.0153906222854723	0.020271757680103